WorldWideScience

Sample records for current high resolution

  1. A PICTORIAL PRESENTATION OF ESOPHAGEAL HIGH RESOLUTION MANOMETRY CURRENT PARAMETERS.

    Science.gov (United States)

    Lafraia, Fernanda M; Herbella, Fernando A M; Kalluf, Julia R; Patti, Marco G

    2017-01-01

    High resolution manometry is the current technology used to the study of esophageal motility and is replacing conventional manometry in important centers for esophageal motility with parameters used on esophageal motility, following the Chicago Classification. This classification unifies high resolution manometry interpretation and classifies esophageal disorders. This review shows, in a pictorial presentation, the new parameters established by the Chicago Classification, version 3.0, aimed to allow an easy comprehension and interpretation of high resolution manometry. Esophageal manometries performed by the authors were reviewed to select illustrative tracings representing Chicago Classification parameters. The parameters are: Esophagogastric Morphology, that classifies this junction according to its physiology and anatomy; Integrated Relaxation Pressure, that measures the lower esophageal sphincter relaxation; Distal Contractile Integral, that evaluates the contraction vigor of each wave; and, Distal Latency, that measures the peristalsis velocity from the beginning of the swallow to the epiphrenic ampulla. Clinical applications of these new concepts is still under evaluation. Mostrar, de forma pictórica, os novos parâmetros compilados na versão 3.0 da Classificação de Chicago, buscando facilitar a compreensão e interpretação da manometria de alta resolução. Foram revistas as manometrias da casuística dos autores e selecionados os traçados representativos dos parâmetros da Classificação de Chicago. Entre os parâmetros apresentados foram considerados a Morfologia da Transição Gastroesofágica, que classifica o segmento de acordo com sua fisiologia e anatomia; a Integral da Pressão de Relaxamento, que mede o relaxamento do esfíncter esofagiano inferior; a Integral Contrátil Distal, que avalia o vigor contrátil da onda peristáltica; e, a Latência Distal, que mede o tempo da peristalse, desde o início da deglutição até a ampola epifr

  2. High resolution modelling of the North Icelandic Irminger Current (NIIC

    Directory of Open Access Journals (Sweden)

    K. Logemann

    2006-01-01

    Full Text Available The northward inflow of Atlantic Water through Denmark Strait – the North Icelandic Irminger Current (NIIC – is simulated with a numerical model of the North Atlantic and Arctic Ocean. The model uses the technique of adaptive grid refinement which allows a high spatial resolution (1 km horizontal, 10 m vertical around Iceland. The model is used to assess time and space variability of volume and heat fluxes for the years 1997–2003. Passive tracers are applied to study origin and composition of NIIC water masses. The NIIC originates from two sources: the Irminger Current, flowing as part of the sub-polar gyre in 100–500 m depth along the Reykjanes Ridge and the shallow Icelandic coastal current, flowing north-westward on the south-west Icelandic shelf. The ratio of volume flux between the deep and shallow branch is around 2:1. The NIIC continues as a warm and saline branch northward through Denmark Strait where it entrains large amounts of polar water due to the collision with the southward flowing East Greenland Current. After passing Denmark Strait, the NIIC follows the coast line eastward being an important heat source for north Icelandic waters. At least 60% of the temporal temperature variability of north Icelandic waters is caused by the NIIC. The NIIC volume and heat transport is highly variable and depends strongly on the wind field north-east of Denmark Strait. Daily means can change from 1 Sv eastward to 2 Sv westward within a few days. Highest monthly mean transport rates occur in summer when winds from north are weak, whereas the volume flux is reduced by around 50% in winter. Summer heat flux rates can be even three times higher than in winter. The simulation also shows variability on the interannual scale. In particular weak winds from north during winter 2002/2003 combined with mild weather conditions south of Iceland led to anomalous high NIIC volume (+40% and heat flux (+60% rates. In this period, simulated north Icelandic

  3. The Tsushima Warm Current from a High Resolution Ocean Prediction Model, HYCOM

    Directory of Open Access Journals (Sweden)

    Seongbong Seo

    2013-06-01

    Full Text Available This study investigates the characteristic of the Tsushima Warm Current from an assimilated high resolution global ocean prediction model, 1/12o Global HYbrid Coordiate Ocean Model (HYCOM. The model results were verified through a comparison with current measurements obtained by acoustic Doppler current profiler (ADCP mounted on the passenger ferryboat between Busan, Korea, and Hakata, Japan. The annual mean transport of the Tsushima Warm Current was 2.56 Sverdrup (Sv (1 Sv = 106 m3s−1, which is similar to those from previous studies (Takikawa et al. 1999; Teague et al. 2002. The volume transport time series of the Tsushima Warm Current from HYCOM correlates to a high degree with that from the ADCP observation (the correlation coefficient between the two is 0.82. The spatiotemporal structures of the currents as well as temperature and salinity from HYCOM are comparable to the observed ones.

  4. High resolution laser beam induced current images under trichromatic laser radiation: approximation to the solar irradiation.

    Science.gov (United States)

    Navas, F J; Alcántara, R; Fernández-Lorenzo, C; Martín-Calleja, J

    2010-03-01

    A laser beam induced current (LBIC) map of a photoactive surface is a very useful tool when it is necessary to study the spatial variability of properties such as photoconverter efficiency or factors connected with the recombination of carriers. Obtaining high spatial resolution LBIC maps involves irradiating the photoactive surface with a photonic beam with Gaussian power distribution and with a low dispersion coefficient. Laser emission fulfils these characteristics, but against it is the fact that it is highly monochromatic and therefore has a spectral distribution different to solar emissions. This work presents an instrumental system and procedure to obtain high spatial resolution LBIC maps in conditions approximating solar irradiation. The methodology developed consists of a trichromatic irradiation system based on three sources of laser excitation with emission in the red, green, and blue zones of the electromagnetic spectrum. The relative irradiation powers are determined by either solar spectrum distribution or Planck's emission formula which provides information approximate to the behavior of the system if it were under solar irradiation. In turn, an algorithm and a procedure have been developed to be able to form images based on the scans performed by the three lasers, providing information about the photoconverter efficiency of photovoltaic devices under the irradiation conditions used. This system has been checked with three photosensitive devices based on three different technologies: a commercial silicon photodiode, a commercial photoresistor, and a dye-sensitized solar cell. These devices make it possible to check how the superficial quantum efficiency has areas dependent upon the excitation wavelength while it has been possible to measure global incident photon-to-current efficiency values approximating those that would be obtained under irradiation conditions with sunlight.

  5. High-resolution velocimetry in energetic tidal currents using a convergent-beam acoustic Doppler profiler

    Energy Technology Data Exchange (ETDEWEB)

    Sellar, Brian [Univ. of Edinburgh, Scotland (United Kingdom); Harding, Samuel F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Richmond, Marshall C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-07-16

    An array of convergent acoustic Doppler velocimeters has been developed and tested for the high resolution measurement of three-dimensional tidal flow velocities in an energetic tidal site. This configuration has been developed to increase spatial resolution of velocity measurements in comparison to conventional acoustic Doppler profilers (ADPs) which characteristically use diverging acoustic beams emanating from a single instrument. This is achieved using converging acoustic beams with a sample volume at the focal point of 0.03 m3. The array is also able to simultaneously measure three-dimensional velocity components in a profile throughout the water column, and as such is referred to herein as a converging-beam acoustic Doppler profiler (CADP). Mid-depth profiling is achieved through integration of the sensor platform with the operational Alstom 1MW DeepGen-IV Tidal Turbine. This proof-of-concept paper outlines system configuration and comparison to measurements provided by co-installed reference instrumentation. Comparison of CADP to standard ADP velocity measurements reveals a mean difference of 8 mm/s, standard deviation of 18 mm/s, and order-of-magnitude reduction in realizable length-scale. CADP focal point measurements compared to a proximal single-beam reference show peak cross-correlation coefficient of 0.96 over 4.0 s averaging period and a 47% reduction in Doppler noise. The dual functionality of the CADP as a profiling instrument with a high resolution focal point make this configuration a unique and valuable advancement in underwater velocimetry enabling improved turbulence, resource and structural loading quantification and validation of numerical simulations. Alternative modes of operation have been implemented including noise-reducing bi-static sampling. Since waves are simultaneously measured it is expected that derivatives of this system will be a powerful tool in wave-current interaction studies.

  6. Cranial electrotherapy stimulation and transcranial pulsed current stimulation: a computer based high-resolution modeling study.

    Science.gov (United States)

    Datta, Abhishek; Dmochowski, Jacek P; Guleyupoglu, Berkan; Bikson, Marom; Fregni, Felipe

    2013-01-15

    The field of non-invasive brain stimulation has developed significantly over the last two decades. Though two techniques of noninvasive brain stimulation--transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)--are becoming established tools for research in neuroscience and for some clinical applications, related techniques that also show some promising clinical results have not been developed at the same pace. One of these related techniques is cranial electrotherapy stimulation (CES), a class of transcranial pulsed current stimulation (tPCS). In order to understand further the mechanisms of CES, we aimed to model CES using a magnetic resonance imaging (MRI)-derived finite element head model including cortical and also subcortical structures. Cortical electric field (current density) peak intensities and distributions were analyzed. We evaluated different electrode configurations of CES including in-ear and over-ear montages. Our results confirm that significant amounts of current pass the skull and reach cortical and subcortical structures. In addition, depending on the montage, induced currents at subcortical areas, such as midbrain, pons, thalamus and hypothalamus are of similar magnitude than that of cortical areas. Incremental variations of electrode position on the head surface also influence which cortical regions are modulated. The high-resolution modeling predictions suggest that details of electrode montage influence current flow through superficial and deep structures. Finally we present laptop based methods for tPCS dose design using dominant frequency and spherical models. These modeling predictions and tools are the first step to advance rational and optimized use of tPCS and CES.

  7. HIGH-RESOLUTION MONITORING OF CURRENT RAPID TRANSFORMATIONS ON GLACIAL AND PERIGLACIAL ENVIRONMENTS

    Directory of Open Access Journals (Sweden)

    L. Carturan

    2014-01-01

    Full Text Available Glacial and periglacial environments are highly sensitive to climatic changes. Processes of cryosphere degradation may strongly impact human activities and infrastructures, and need to be monitored for improved understanding and for mitigation/adaptation. Studying glacial and periglacial environments using traditional techniques may be difficult or not feasible, but new remote sensing techniques like terrestrial and aerial laser scanner opened new possibilities for cryospheric studies. This work presents an application of the terrestrial laser scanner (TLS for monitoring the current rapid changes occurring on the Montasio Occidentale glacier (Eastern Italian alps, which is representative of low-altitude, avalanche-fed and debris-cover glaciers. These glaciers are quite common in the Alps but their reaction to climate changes is still poorly known. The mass balance, surface velocity fields, debris cover dynamics and effects of meteorological extremes were investigated by repeat high-resolution TLS scanning from September 2010 to October 2012. The results were encouraging and shed light on the peculiar response of this glacier to climatic changes, on its current dynamics and on the feedback played by the debris cover, which is critical for its preservation. The rapid transformations in act, combined with the unstable ice mass, large amount of loose debris and channeled runoff during intense rainfalls, constitute a potential area for the formation of large debris flows, as shown by field evidences and documented by the recent literature.

  8. High-resolution velocimetry in energetic tidal currents using a convergent-beam acoustic Doppler profiler

    Science.gov (United States)

    Sellar, Brian; Harding, Samuel; Richmond, Marshall

    2015-08-01

    An array of single-beam acoustic Doppler profilers has been developed for the high resolution measurement of three-dimensional tidal flow velocities and subsequently tested in an energetic tidal site. This configuration has been developed to increase spatial resolution of velocity measurements in comparison to conventional acoustic Doppler profilers (ADPs) which characteristically use divergent acoustic beams emanating from a single instrument. This is achieved using geometrically convergent acoustic beams creating a sample volume at the focal point of 0.03 m3. Away from the focal point, the array is also able to simultaneously reconstruct three-dimensional velocity components in a profile throughout the water column, and is referred to herein as a convergent-beam acoustic Doppler profiler (C-ADP). Mid-depth profiling is achieved through integration of the sensor platform with the operational commercial-scale Alstom 1 MW DeepGen-IV Tidal Turbine deployed at the European Marine Energy Center, Orkney Isles, UK. This proof-of-concept paper outlines the C-ADP system configuration and comparison to measurements provided by co-installed reference instrumentation. Comparison of C-ADP to standard divergent ADP (D-ADP) velocity measurements reveals a mean difference of 8 mm s-1, standard deviation of 18 mm s-1, and an order of magnitude reduction in realisable length scale. C-ADP focal point measurements compared to a proximal single-beam reference show peak cross-correlation coefficient of 0.96 over 4.0 s averaging period and a 47% reduction in Doppler noise. The dual functionality of the C-ADP as a profiling instrument with a high resolution focal point make this configuration a unique and valuable advancement in underwater velocimetry enabling improved quantification of flow turbulence. Since waves are simultaneously measured via profiled velocities, pressure measurements and surface detection, it is expected that derivatives of this system will be a powerful tool in

  9. Air-sea Energy Transfer at Mesoscale in a Coupled High-resolution Model: Impact of Resolution and Current Feedback

    Science.gov (United States)

    Jullien, S.; Colas, F.; Masson, S. G.; Oerder, V.; Echevin, V.; Samson, G.; Crétat, J.; Berthet, S.; Hourdin, C.

    2015-12-01

    Winds are usually considered to force the ocean but recent studies suggested that oceanic mesoscale activity, characterized by eddies, filaments and fronts, could also affect the wind field. These structures feature abrupt changes in sea surface temperature (SST), surface pressure and surface currents that could impact the atmosphere by enhancing/reducing air-sea fluxes, accelerating/decelerating winds, modifying the wind-pressure balance… At this time, the detailed processes associated to such coupling, its intensity and significance remain a matter of research. Here, a state-of-the-art WRF-OASIS-NEMO coupled model is set up over a wide tropical channel (45°S-45°N) at various resolutions: 3/4°, 1/4° and 1/12° in both the ocean and the atmosphere. Several experiments are conducted in forced, partially or fully coupled modes, to highlight the effect of resolution and the role of SST vs. current feedback to energy injection into the ocean and the atmosphere. In strong mesoscale activity regions, a negative wind power input from the atmosphere to the ocean is seen at scales ranging from 100km to more than 1000km. Nonexistent at 3/4°, this negative forcing, acting against oceanic mesoscale activity, is almost twice more important at 1/12° than at 1/4°. In addition, partially coupled simulations, i.e. without current feedback, show that the impact of thermal coupling on this process is very limited. Energy injection to the marine atmospheric boundary layer also features imprints from oceanic mesoscale. Energy injection by scales shorter than 300km represents up to 20% of the total. Finally we show that increasing oceanic resolution, and therefore mesoscale activity, is necessary to resolve the full wind stress spectrum and has an upscaling effect by enhancing atmospheric mesoscale, which is larger scale than in the ocean. Using 1/4°oceanic resolution instead of 1/12° leads to a 50% loss of energy in the atmospheric mesoscale.

  10. Quantifying the erosion effect on current carbon budget of European agricultural soils at high spatial resolution.

    Science.gov (United States)

    Lugato, Emanuele; Paustian, Keith; Panagos, Panos; Jones, Arwyn; Borrelli, Pasquale

    2016-05-01

    The idea of offsetting anthropogenic CO2 emissions by increasing global soil organic carbon (SOC), as recently proposed by French authorities ahead of COP21 in the 'four per mil' initiative, is notable. However, a high uncertainty still exits on land C balance components. In particular, the role of erosion in the global C cycle is not totally disentangled, leading to disagreement whether this process induces lands to be a source or sink of CO2. To investigate this issue, we coupled soil erosion into a biogeochemistry model, running at 1 km(2) resolution across the agricultural soils of the European Union (EU). Based on data-driven assumptions, the simulation took into account also soil deposition within grid cells and the potential C export to riverine systems, in a way to be conservative in a mass balance. We estimated that 143 of 187 Mha have C erosion rates 0.45 Mg C ha(-1) yr(-1). In comparison with a baseline without erosion, the model suggested an erosion-induced sink of atmospheric C consistent with previous empirical-based studies. Integrating all C fluxes for the EU agricultural soils, we estimated a net C loss or gain of -2.28 and +0.79 Tg yr(-1) of CO2 eq, respectively, depending on the value for the short-term enhancement of soil C mineralization due to soil disruption and displacement/transport with erosion. We concluded that erosion fluxes were in the same order of current carbon gains from improved management. Even if erosion could potentially induce a sink for atmospheric CO2, strong agricultural policies are needed to prevent or reduce soil erosion, in order to maintain soil health and productivity.

  11. Current use of high-resolution mass spectrometry in the environmental sciences

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, F.; Sancho, J.V.; Ibanez, M.; Portoles, T. [University Jaume I, Research Institute for Pesticides and Water, Castellon (Spain); Abad, E.; Mattioli, L. [IDAEA-CSIC, Laboratory of Dioxins, Department of Environmental Chemistry, Barcelona (Spain)

    2012-05-15

    During the last two decades, mass spectrometry (MS) has been increasingly used in the environmental sciences with the objective of investigating the presence of organic pollutants. MS has been widely coupled with chromatographic techniques, both gas chromatography (GC) and liquid chromatography (LC), because of their complementary nature when facing a broad range of organic pollutants of different polarity and volatility. A clear trend has been observed, from the very popular GC-MS with a single quadrupole mass analyser, to tandem mass spectrometry (MS-MS) and, more recently, high-resolution mass spectrometry (HRMS). For years GC has been coupled to HR magnetic sector instruments, mostly for dioxin analysis, although in the last ten years there has been growing interest in HRMS with time-of-flight (TOF) and Orbitrap mass analyzers, especially in LC-MS analysis. The increasing interest in the use of HRMS in the environmental sciences is because of its suitability for both targeted and untargeted analysis, owing to its sensitivity in full-scan acquisition mode and high mass accuracy. With the same instrument one can perform a variety of tasks: pre- and post-target analysis, retrospective analysis, discovery of metabolite and transformation products, and non-target analysis. All these functions are relevant to the environmental sciences, in which the analyst encounters thousands of different organic contaminants. Thus, wide-scope screening of environmental samples is one of the main applications of HRMS. This paper is a critical review of current use of HRMS in the environmental sciences. Needless to say, it is not the intention of the authors to summarise all contributions of HRMS in this field, as in classic descriptive reviews, but to give an overview of the main characteristics of HRMS, its strong potential in environmental mass spectrometry and the trends observed over the last few years. Most of the literature has been acquired since 2005, coinciding with the

  12. Presal36: a high resolution ocean current model for Brazilian pre-salt area: implementation and validation results

    Energy Technology Data Exchange (ETDEWEB)

    Schoellkopf, Jacques P. [Advanced Subsea do Brasil Ltda., Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The PRESAL 36 JIP is a project for the development of a powerful Ocean Current Model of 1/36 of a degree resolution, nested in an existing Global Ocean global Model, Mercator PSY4 (1/12-a-degree resolution ), with tide corrections, improved bathymetry accuracy and high frequency atmospheric forcing (every 3 hours). The simulation outputs will be the 3 dimensional structure of the velocity fields (u,v,w) at 50 vertical levels over the water column, including geostrophic, Ekman and tidal currents, together with Temperature, Salinity and sea surface height at a sub-mesoscale spatial resolution. Simulations will run in hindcast, nowcast and forecast modes, with a temporal resolution of 3 hours . This Ocean current model will allow to perform detailed statistical studies on various areas using conditions analysed using hindcast mode, short term operational condition prediction for various surface and sub sea operations using realtime and Forecast modes. The paper presents a publication of significant results of the project, in term of pre-sal zoomed model implementation, and high resolution model validation. It demonstrate the capability to properly describe ocean current phenomenon at beyond mesoscale frontier. This project demonstrate the feasibility of obtaining accurate information for engineering studies and operational conditions, based on a 'zoom technique' starting from global ocean models. (author)

  13. EGATEC: A new high-resolution engineering model of the global atmospheric electric circuit—Currents in the lower atmosphere

    Science.gov (United States)

    Odzimek, A.; Lester, M.; Kubicki, M.

    2010-09-01

    We present a new high-resolution model of the Earth's global atmospheric electric circuit (GEC) represented by an equivalent electrical network. Contributions of clouds to the total resistance of the atmosphere and as current generators are treated more realistically than in previous GEC models. The model of cloud current generators is constructed on the basis of the ISCCP cloud data and the OTD/LIS lightning flash rates and TRMM rainfall data. The current generated and the electric resistance can be estimated with a spatial resolution of several degrees in latitude and longitude and 3 hour time resolution. The resistance of the atmosphere is calculated using an atmospheric conductivity model which is spatially dependent and sensitive to the level of solar activity. An equivalent circuit is constructed assuming the ionosphere and ground are ideal conductors. The circuit solution provides diurnal variations of the ionospheric potential and the GEC global current at the 3 hour time resolution as well as the global distributions and diurnal variations of the air-Earth current density and electric field. The model confirms that the global atmospheric electric activity peaks daily at ˜21 UT. The diurnal variation of the ionospheric potential and the global current have a maximum at 12 and 21-24 UT in July and at 9 and 21 UT in December, and a global minimum at 3-6 UT independent of season. About 80% of the current is generated by thunderstorm convective clouds and 20% by mid-level rain clouds.

  14. High resolution modelling and observation of wind-driven surface currents in a semi-enclosed estuary

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    Nash, S.; Hartnett, M.; McKinstry, A.; Ragnoli, E.; Nagle, D.

    2012-04-01

    Hydrodynamic circulation in estuaries is primarily driven by tides, river inflows and surface winds. While tidal and river data can be quite easily obtained for input to hydrodynamic models, sourcing accurate surface wind data is problematic. Firstly, the wind data used in hydrodynamic models is usually measured on land and can be quite different in magnitude and direction from offshore winds. Secondly, surface winds are spatially-varying but due to a lack of data it is common practice to specify a non-varying wind speed and direction across the full extents of a model domain. These problems can lead to inaccuracies in the surface currents computed by three-dimensional hydrodynamic models. In the present research, a wind forecast model is coupled with a three-dimensional numerical model of Galway Bay, a semi-enclosed estuary on the west coast of Ireland, to investigate the effect of surface wind data resolution on model accuracy. High resolution and low resolution wind fields are specified to the model and the computed surface currents are compared with high resolution surface current measurements obtained from two high frequency SeaSonde-type Coastal Ocean Dynamics Applications Radars (CODAR). The wind forecast models used for the research are Harmonie cy361.3, running on 2.5 and 0.5km spatial grids for the low resolution and high resolution models respectively. The low-resolution model runs over an Irish domain on 540x500 grid points with 60 vertical levels and a 60s timestep and is driven by ECMWF boundary conditions. The nested high-resolution model uses 300x300 grid points on 60 vertical levels and a 12s timestep. EFDC (Environmental Fluid Dynamics Code) is used for the hydrodynamic model. The Galway Bay model has ten vertical layers and is resolved spatially and temporally at 150m and 4 sec respectively. The hydrodynamic model is run for selected hindcast dates when wind fields were highly energetic. Spatially- and temporally-varying wind data is provided by

  15. High-resolution simulations for Vietnam - methodology and evaluation of current climate

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    Katzfey, Jack; Nguyen, Kim; McGregor, John; Hoffmann, Peter; Ramasamy, Suppiah; Nguyen, Hiep Van; Khiem, Mai Van; Nguyen, Thang Van; Truong, Kien Ba; Vu, Thang Van; Nguyen, Hien Thuan; Thuc, Tran; Phong, Doan Ha; Nguyen, Bang Thanh; Phan-Van, Tan; Nguyen-Quang, Trung; Ngo-Duc, Thanh; Trinh-Tuan, Long

    2016-05-01

    To assist the government of Vietnam in its efforts to better understand the impacts of climate change and prioritise its adaptation measures, dynamically downscaled climate change projections were produced across Vietnam. Two Regional Climate Models (RCMs) were used: CSIRO's variable-resolution Conformal-Cubic Atmospheric Model (CCAM) and the limited-area model Regional Climate Model system version 4.2 (RegCM4.2). First, global CCAM simulations were completed using bias- and variance-corrected sea surface temperatures as well as sea ice concentrations from six Coupled Model Intercomparison Project Phase 5 (CMIP5) global climate models. This approach is different from other downscaling approaches as it does not use any atmospheric fields from the GCMs. The global CCAM simulations were then further downscaled to 10 km using CCAM and to 20 km using RegCM4.2. Evaluations of temperature and precipitation for the current climate (1980-2000) were completed using station data as well as various gridded observational datasets. The RCMs were able to reproduce reasonably well most of the important characteristics of observed spatial patterns and annual cycles of temperature. Average and minimum temperatures were well simulated (biases generally less than 1oC), while maximum temperatures had biases of around 1oC. For precipitation, although the RCMs captured the annual cycle, RegCM4.2 was too dry in Oct.-Nov. (-60% bias), while CCAM was too wet in Dec.- Mar. (130% bias). Both models were too dry in summer and too wet in winter (especially in northern Vietnam). The ability of the ensemble simulations to capture current climate increases confidence in the simulations of future climate.

  16. High-Resolution Chromosome Ideogram Representation of Currently Recognized Genes for Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Merlin G. Butler

    2015-03-01

    Full Text Available Recently, autism-related research has focused on the identification of various genes and disturbed pathways causing the genetically heterogeneous group of autism spectrum disorders (ASD. The list of autism-related genes has significantly increased due to better awareness with advances in genetic technology and expanding searchable genomic databases. We compiled a master list of known and clinically relevant autism spectrum disorder genes identified with supporting evidence from peer-reviewed medical literature sources by searching key words related to autism and genetics and from authoritative autism-related public access websites, such as the Simons Foundation Autism Research Institute autism genomic database dedicated to gene discovery and characterization. Our list consists of 792 genes arranged in alphabetical order in tabular form with gene symbols placed on high-resolution human chromosome ideograms, thereby enabling clinical and laboratory geneticists and genetic counsellors to access convenient visual images of the location and distribution of ASD genes. Meaningful correlations of the observed phenotype in patients with suspected/confirmed ASD gene(s at the chromosome region or breakpoint band site can be made to inform diagnosis and gene-based personalized care and provide genetic counselling for families.

  17. Currently recognized genes for schizophrenia: High-resolution chromosome ideogram representation.

    Science.gov (United States)

    Butler, Merlin G; McGuire, Austen B; Masoud, Humaira; Manzardo, Ann M

    2016-03-01

    A large body of genetic data from schizophrenia-related research has identified an assortment of genes and disturbed pathways supporting involvement of complex genetic components for schizophrenia spectrum and other psychotic disorders. Advances in genetic technology and expanding studies with searchable genomic databases have led to multiple published reports, allowing us to compile a master list of known, clinically relevant, or susceptibility genes contributing to schizophrenia. We searched key words related to schizophrenia and genetics from peer-reviewed medical literature sources, authoritative public access psychiatric websites and genomic databases dedicated to gene discovery and characterization of schizophrenia. Our list of 560 genes were arranged in alphabetical order in tabular form with gene symbols placed on high-resolution human chromosome ideograms. Genome wide pathway analysis using GeneAnalytics was carried out on the resulting list of genes to assess the underlying genetic architecture for schizophrenia. Recognized genes of clinical relevance, susceptibility or causation impact a broad range of biological pathways and mechanisms including ion channels (e.g., CACNA1B, CACNA1C, CACNA1H), metabolism (e.g., CYP1A2, CYP2C19, CYP2D6), multiple targets of neurotransmitter pathways impacting dopamine, GABA, glutamate, and serotonin function, brain development (e.g., NRG1, RELN), signaling peptides (e.g., PIK3CA, PIK4CA) and immune function (e.g., HLA-DRB1, HLA-DQA1) and interleukins (e.g., IL1A, IL10, IL6). This summary will enable clinical and laboratory geneticists, genetic counselors, and other clinicians to access convenient pictorial images of the distribution and location of contributing genes to inform diagnosis and gene-based treatment as well as provide risk estimates for genetic counseling of families with affected relatives.

  18. High resolution simulations of down-slope turbidity currents into stratified saline ambient

    Science.gov (United States)

    Ouillon, Raphael; Radhakrishnan, Senthil; Meiburg, Eckart; Sutherland, Bruce

    2016-11-01

    In this work we explore the properties of turbidity currents moving down a slope into a stratified saline ambient through highly resolved 3D Navier-Stokes simulations. Turbidity events are difficult to measure and to replicate experimentally for a wide range of parameters, but they play a key role in ocean, lake or river sediment transport. Our objectives are to improve on previous numerical studies, obtain quantitative data in a more controlled environment than current experimental set-ups, and combine results with analytical arguments to build physics-based scaling laws. We validate our results and propose a simple scaling law to predict the velocity of the front down a slope for any stratification. We also compute a time and space dependent entrainment of ambient fluid and highlight its strong variability. We then introduce a predictable scaling law for the intrusion depth that does not depend on an averaged entrainment and uses it as a verification tool instead. Finally, we show that the ratio of Stokes losses in the local flow around individual particles to dissipative losses of the large scale flow determines the ability of the flow to convert potential energy into kinetic energy. For different parameters, either mechanism can dominate the dynamics of the flow.

  19. High Resolution Simulation of a Colorado Rockies Extreme Snow and Rain Event in both a Current and Future Climate

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    Rasmussen, Roy; Ikeda, Kyoko; Liu, Changhai; Gutmann, Ethan; Gochis, David

    2016-04-01

    Modeling of extreme weather events often require very finely resolved treatment of atmospheric circulation structures in order to produce and localize the large moisture fluxes that result in extreme precipitation. This is particularly true for cool season orographic precipitation processes where the representation of the landform can significantly impact vertical velocity profiles and cloud moisture entrainment rates. This study presents results for high resolution regional climate modeling study of the Colorado Headwaters region using an updated version of the Weather Research and Forecasting (WRF) model run at 4 km horizontal resolution and a hydrological extension package called WRF-Hydro. Previous work has shown that the WRF modeling system can produce credible depictions of winter orographic precipitation over the Colorado Rockies if run at horizontal resolutions warming on total precipitation, snow-rain partitioning and surface hydrological fluxes (evapotranspiration and runoff) will be discussed in the context of how potential changes in temperature impact the amount of precipitation, the phase of precipitation (rain vs. snow) and the timing and amplitude of streamflow responses. The results show using the Pseudo Global Warming technique that intense precipitation rates significantly increased during the event and a significant fraction of the snowfall converts to rain which significantly amplifies the runoff response from one where runoff is produced gradually to one in which runoff is rapidly translated into streamflow values that approach significant flooding risks. Results from a new, CONUS scale high resolution climate simulation of extreme events in a current and future climate will be presented as time permits.

  20. Design automation techniques for high-resolution current folding and interpolating CMOS A/D converters

    Science.gov (United States)

    Gevaert, D.

    2007-05-01

    The design and testing of a 12-bit Analog-to-Digital (A/D) converter, in current mode, arranged in an 8-bit LSB and a 4- bit MSB architecture together with the integration of specialized test building blocks on chip allows the set up of a design automation technique for current folding and interpolation CMOS A/D converter architectures. The presented design methodology focuses on the automation for CMOS A/D building blocks in a flexible target current folding and interpolating architecture for a downscaling technology and for different quality specifications. The comprehensive understanding of all sources of mismatching in the crucial building blocks and the use of physical based mismatch modeling in the prediction of mismatch errors, more adequate and realistic sizing of all transistors will result in an overall area reduction of the A/D converter. In this design the folding degree is 16, the number of folders is 64 and the interpolation level is 4. The number of folders is reduced by creating intermediate folding signals with a 4-level interpolator based on current division techniques. Current comparators detect the zero-crossing between the differential folder output currents. The outputs of the comparators deliver a cyclic thermometer code. The digital synthesis part for decoding and error correction building blocks is a standardized digital standard cell design. The basic building blocks in the target architecture were designed in 0.35μ CMOS technology; they are suitable for topological reuse and are in an automated way downscaled into a 0.18μ CMOS technology.

  1. A High-Resolution, Wave and Current Resource Assessment of Japan: The Web GIS Dataset

    CERN Document Server

    Webb, Adrean; Fujimoto, Wataru; Horiuchi, Kazutoshi; Kiyomatsu, Keiji; Matsuda, Kazuhiro; Miyazawa, Yasumasa; Varlamov, Sergey; Yoshikawa, Jun

    2016-01-01

    The University of Tokyo and JAMSTEC have conducted state-of-the-art wave and current resource assessments to assist with generator site identification and construction in Japan. These assessments are publicly-available and accessible via a web GIS service designed by WebBrain that utilizes TDS and GeoServer software with Leaflet libraries. The web GIS dataset contains statistical analyses of wave power, ocean and tidal current power, ocean temperature power, and other basic physical variables. The data (2D maps, time charts, depth profiles, etc.) is accessed through interactive browser sessions and downloadable files.

  2. A 20-Year High-Resolution Wave Resource Assessment of Japan with Wave-Current Interactions

    Science.gov (United States)

    Webb, A.; Waseda, T.; Kiyomatsu, K.

    2016-02-01

    Energy harvested from surface ocean waves and tidal currents has the potential to be a significant source of green energy, particularly for countries with extensive coastlines such as Japan. As part of a larger marine renewable energy project*, The University of Tokyo (in cooperation with JAMSTEC) has conducted a state-of-the-art wave resource assessment (with uncertainty estimates) to assist with wave generator site identification and construction in Japan. This assessment will be publicly available and is based on a large-scale NOAA WAVEWATCH III (version 4.18) simulation using NCEP and JAMSTEC forcings. It includes several key components to improve model skill: a 20-year simulation to reduce aleatory uncertainty, a four-nested-layer approach to resolve a 1 km shoreline, and finite-depth and current effects included in all wave power density calculations. This latter component is particularly important for regions near strong currents such as the Kuroshio. Here, we will analyze the different wave power density equations, discuss the model setup, and present results from the 20-year assessment (with a focus on the role of wave-current interactions). Time permitting, a comparison will also be made with simulations using JMA MSM 5 km winds. *New Energy and Industrial Technology Development Organization (NEDO): "Research on the Framework and Infrastructure of Marine Renewable Energy; an Energy Potential Assessment"

  3. New turbidity current model based on high-resolution monitoring of the longest flow ever measured

    Science.gov (United States)

    Azpiroz, Maria; Cartigny, Matthieu; Talling, Peter; Parsons, Daniel; Simmons, Steve; Clare, Michael; Sumner, Esther; Pope, Ed

    2016-04-01

    Turbidity currents transport large amounts of sediment from shallow waters towards deep ocean basins. Little is known about these flows, despite their potential hazard for damaging expensive and strategically important seafloor infrastructure. So far turbidity currents have been profiled in only 6 deep ocean locations worldwide. Our current knowledge of these flows is therefore mainly based on scaled-down experimental and computationally-limited numerical modelling. Here we present results from the monitoring of a one-week long turbidity current in the Congo Canyon that had a discharge close to that of the Mississippi River. Measurements taken every 5 seconds give the most detailed image yet of a turbidity current deep-water over an unprecedented duration. Our analysis reveals a different flow structure than that presented in previous models. Classical models display a thick front of the flow followed by a thinner and faster flow, which gives way to a short and quasi-steady body. Instead, we observe a thin frontal cell that outruns a thicker (~80 m), long and slower quasi-steady flow. In contrast to the previous model, where the thinner faster flow feeds sediment into the head, the Congo Canyon turbidity current shows a frontal cell that feeds sediment into, and at the same time outruns, the succeeding quasi-steady flow. As a result of the faster moving frontal cell, the flow should continuously stretch and grow in length while propagating down the system. Within the quasi-steady body, the flow switches between what appears to be two stable flow modes. One mode exhibits a fast and thin velocity profile whose maximum is a low distance from the seabed and resembles Froude-supercritical flow conditions, while the other mode is similar to Froude-subcritical flow conditions as the flow is thicker and slower. These first observations provide new insights into the behaviour of deep water long duration flows that differ from traditional models and provide an exciting

  4. The role of high-resolution geomagnetic field models for investigating ionospheric currents at low Earth orbit satellites

    Science.gov (United States)

    Stolle, Claudia; Michaelis, Ingo; Rauberg, Jan

    2016-07-01

    Low Earth orbiting geomagnetic satellite missions, such as the Swarm satellite mission, are the only means to monitor and investigate ionospheric currents on a global scale and to make in situ measurements of F region currents. High-precision geomagnetic satellite missions are also able to detect ionospheric currents during quiet-time geomagnetic conditions that only have few nanotesla amplitudes in the magnetic field. An efficient method to isolate the ionospheric signals from satellite magnetic field measurements has been the use of residuals between the observations and predictions from empirical geomagnetic models for other geomagnetic sources, such as the core and lithospheric field or signals from the quiet-time magnetospheric currents. This study aims at highlighting the importance of high-resolution magnetic field models that are able to predict the lithospheric field and that consider the quiet-time magnetosphere for reliably isolating signatures from ionospheric currents during geomagnetically quiet times. The effects on the detection of ionospheric currents arising from neglecting the lithospheric and magnetospheric sources are discussed on the example of four Swarm orbits during very quiet times. The respective orbits show a broad range of typical scenarios, such as strong and weak ionospheric signal (during day- and nighttime, respectively) superimposed over strong and weak lithospheric signals. If predictions from the lithosphere or magnetosphere are not properly considered, the amplitude of the ionospheric currents, such as the midlatitude Sq currents or the equatorial electrojet (EEJ), is modulated by 10-15 % in the examples shown. An analysis from several orbits above the African sector, where the lithospheric field is significant, showed that the peak value of the signatures of the EEJ is in error by 5 % in average when lithospheric contributions are not considered, which is in the range of uncertainties of present empirical models of the EEJ.

  5. Old relief printing applied to the current preparation of multi-color and high resolution colloidal photonic crystal patterns.

    Science.gov (United States)

    Yang, Dongpeng; Ye, Siyun; Ge, Jianping

    2015-12-11

    Monodisperse SiO2 colloids are assembled into colloidal crystals in the mixture of monomer and solvent, which is transformed into a mechanochromic photonic crystal paper by polymerization. Following the relief printing strategy, the printing plates are pressed onto the paper to generate letters or images due to the contrast of structural color between the deformed and the undeformed paper, and the images can be permanently retained through UV curing. The wide tunable range of structural color for the current paper under deformation helps to realize multi-color printing. The localized deformation among or even inside the colloidal microcrystals renders the paper with a precise mechanochromic response to the printing plates and leads to the production of high resolution photonic crystal patterns.

  6. High-resolution electron-beam-induced-current study of the defect structure in GaN epilayers

    CERN Document Server

    Shmidt, N M; Usikov, A S; Yakimov, E B; Zavarin, E E

    2002-01-01

    Electron-beam-induced-current (EBIC) investigations of GaN structures grown by metal-organic chemical vapour deposition on (0001) sapphire substrates have been carried out. It is shown that the widths of the EBIC profiles for individual extended defects can be as small as about 100 nm. This width is observed to decrease with decreasing diffusion length and/or with increasing electron beam energy. The high spatial resolution is explained by the small diffusion length in the samples under study. The diffusion length is small even in structures with dislocation densities of about 10 sup 8 cm sup - sup 3 and carrier mobilities of about 600 cm sup 2 V sup - sup 1 s sup - sup 1 at 300 K and 1800 cm sup 2 V sup - sup 1 s sup - sup 1 at 125 K.

  7. High Resolution Elevation Contours

    Data.gov (United States)

    Minnesota Department of Natural Resources — This dataset contains contours generated from high resolution data sources such as LiDAR. Generally speaking this data is 2 foot or less contour interval.

  8. Ultra high resolution tomography

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  9. Current-Sensing and Voltage-Feedback Driving Method for Large-Area High-Resolution Active Matrix Organic Light Emitting Diodes

    Science.gov (United States)

    In, Hai‑Jung; Choi, Byong‑Deok; Chung, Ho‑Kyoon; Kwon, Oh‑Kyong

    2006-05-01

    There is the problem of picture quality nonuniformity due to thin film transistor (TFT) characteristic variations throughout a panel of large-area high-resolution active matrix organic light emitting diodes. The current programming method could solve this issue, but it also requires very long charging time of a data line at low gray shades. Therefore, we propose a new driving method and a pixel circuit with emission-current sensing and feedback operation in order to resolve these problems. The proposed driving method and pixel circuit successfully compensate threshold voltage and mobility variations of TFTs and overcome the data line charging problem. Simulation results show that emission current deviations of the proposed driving method are less than 1.7% with ± 10.0% mobility and ± 0.3 V threshold voltage variations of pixel-driving TFTs, which means the proposed driving method is applicable to large-area high-resolution applications.

  10. Field testing of a convergent array of acoustic Doppler profilers for high-resolution velocimetry in energetic tidal currents

    Energy Technology Data Exchange (ETDEWEB)

    Harding, Samuel F.; Sellar, Brian; Richmond, Marshall C.

    2016-04-25

    An array of single-beam acoustic Doppler profilers has been developed for the high resolution measurement of three-dimensional tidal flow velocities and subsequently tested in an energetic tidal site. This configuration has been developed to increase spatial resolution of velocity measurements in comparison to conventional acoustic Doppler profilers (ADPs) which characteristically use divergent acoustic beams emanating from a single instrument. This is achieved using geometrically convergent acoustic beams creating a sample volume at the focal point of 0.03 m3. Away from the focal point, the array is also able to simultaneously reconstruct three-dimensional velocity components in a profile throughout the water column, and is referred to herein as a convergent-beam acoustic Doppler profiler (C-ADP). Mid-depth profiling is achieved through integration of the sensor platform with the operational commercial-scale Alstom 1MW DeepGen-IV Tidal Turbine deployed at the European Marine Energy Center, Orkney Isles, UK. This proof-of-concept paper outlines the C-ADP system configuration and comparison to measurements provided by co-installed reference instrumentation.

  11. High-resolution headlamp

    Science.gov (United States)

    Gut, Carsten; Cristea, Iulia; Neumann, Cornelius

    2016-04-01

    The following article shall describe how human vision by night can be influenced. At first, front lighting systems that are already available on the market will be described, followed by their analysis with respect to the positive effects on traffic safety. Furthermore, how traffic safety by night can be increased since the introduction of high resolution headlamps shall be discussed.

  12. High speed, intermediate resolution, large area laser beam induced current imaging and laser scribing system for photovoltaic devices and modules.

    Science.gov (United States)

    Phillips, Adam B; Song, Zhaoning; DeWitt, Jonathan L; Stone, Jon M; Krantz, Patrick W; Royston, John M; Zeller, Ryan M; Mapes, Meghan R; Roland, Paul J; Dorogi, Mark D; Zafar, Syed; Faykosh, Gary T; Ellingson, Randy J; Heben, Michael J

    2016-09-01

    We have developed a laser beam induced current imaging tool for photovoltaic devices and modules that utilizes diode pumped Q-switched lasers. Power densities on the order of one sun (100 mW/cm(2)) can be produced in a ∼40 μm spot size by operating the lasers at low diode current and high repetition rate. Using galvanostatically controlled mirrors in an overhead configuration and high speed data acquisition, large areas can be scanned in short times. As the beam is rastered, focus is maintained on a flat plane with an electronically controlled lens that is positioned in a coordinated fashion with the movements of the mirrors. The system can also be used in a scribing mode by increasing the diode current and decreasing the repetition rate. In either mode, the instrument can accommodate samples ranging in size from laboratory scale (few cm(2)) to full modules (1 m(2)). Customized LabVIEW programs were developed to control the components and acquire, display, and manipulate the data in imaging mode.

  13. High speed, intermediate resolution, large area laser beam induced current imaging and laser scribing system for photovoltaic devices and modules

    Science.gov (United States)

    Phillips, Adam B.; Song, Zhaoning; DeWitt, Jonathan L.; Stone, Jon M.; Krantz, Patrick W.; Royston, John M.; Zeller, Ryan M.; Mapes, Meghan R.; Roland, Paul J.; Dorogi, Mark D.; Zafar, Syed; Faykosh, Gary T.; Ellingson, Randy J.; Heben, Michael J.

    2016-09-01

    We have developed a laser beam induced current imaging tool for photovoltaic devices and modules that utilizes diode pumped Q-switched lasers. Power densities on the order of one sun (100 mW/cm2) can be produced in a ˜40 μm spot size by operating the lasers at low diode current and high repetition rate. Using galvanostatically controlled mirrors in an overhead configuration and high speed data acquisition, large areas can be scanned in short times. As the beam is rastered, focus is maintained on a flat plane with an electronically controlled lens that is positioned in a coordinated fashion with the movements of the mirrors. The system can also be used in a scribing mode by increasing the diode current and decreasing the repetition rate. In either mode, the instrument can accommodate samples ranging in size from laboratory scale (few cm2) to full modules (1 m2). Customized LabVIEW programs were developed to control the components and acquire, display, and manipulate the data in imaging mode.

  14. High Resolution Acoustical Imaging

    Science.gov (United States)

    1989-05-01

    1028 (September 1982). 26 G. Arfken , Mathematical Methods for Physicists (Academic Press, New York, 1971), 2nd printing, pp.662-666. 27 W. R. Hahn...difference in the approach used by the two methods , as noted in the previous paragraph, forming a direct mathematical com- parison may be impossible...examines high resolution methods which use a linear array to locate stationary objects which have scattered the fressure waves. Several;- new methods

  15. High resolution differential thermometer

    Directory of Open Access Journals (Sweden)

    Gotra Z. Yu.

    2009-11-01

    Full Text Available Main schematic solutions of differential thermometers with measurement resolution about 0.001°C are considered. Differential temperature primary transducer realized on a transistor differential circuit in microampere mode. Analytic calculation and schematic mathematic simulation of primary transducer are fulfilled. Signal transducer is realized on a high precision Zero-Drift Single-Supply Rail-to-Rail operation amplifier AD8552 and 24-Bit S-D microconverter ADuC834.

  16. High-resolution climate and land surface interactions modeling over Belgium: current state and decennial scale projections

    Science.gov (United States)

    Jacquemin, Ingrid; Henrot, Alexandra-Jane; Beckers, Veronique; Berckmans, Julie; Debusscher, Bos; Dury, Marie; Minet, Julien; Hamdi, Rafiq; Dendoncker, Nicolas; Tychon, Bernard; Hambuckers, Alain; François, Louis

    2016-04-01

    The interactions between land surface and climate are complex. Climate changes can affect ecosystem structure and functions, by altering photosynthesis and productivity or inducing thermal and hydric stresses on plant species. These changes then impact socio-economic systems, through e.g., lower farming or forestry incomes. Ultimately, it can lead to permanent changes in land use structure, especially when associated with other non-climatic factors, such as urbanization pressure. These interactions and changes have feedbacks on the climate systems, in terms of changing: (1) surface properties (albedo, roughness, evapotranspiration, etc.) and (2) greenhouse gas emissions (mainly CO2, CH4, N2O). In the framework of the MASC project (« Modelling and Assessing Surface Change impacts on Belgian and Western European climate »), we aim at improving regional climate model projections at the decennial scale over Belgium and Western Europe by combining high-resolution models of climate, land surface dynamics and socio-economic processes. The land surface dynamics (LSD) module is composed of a dynamic vegetation model (CARAIB) calculating the productivity and growth of natural and managed vegetation, and an agent-based model (CRAFTY), determining the shifts in land use and land cover. This up-scaled LSD module is made consistent with the surface scheme of the regional climate model (RCM: ALARO) to allow simulations of the RCM with a fully dynamic land surface for the recent past and the period 2000-2030. In this contribution, we analyze the results of the first simulations performed with the CARAIB dynamic vegetation model over Belgium at a resolution of 1km. This analysis is performed at the species level, using a set of 17 species for natural vegetation (trees and grasses) and 10 crops, especially designed to represent the Belgian vegetation. The CARAIB model is forced with surface atmospheric variables derived from the monthly global CRU climatology or ALARO outputs

  17. Direct current (DC) resistivity and induced polarization (IP) monitoring of active layer dynamics at high temporal resolution

    DEFF Research Database (Denmark)

    Doetsch, Joseph; Ingeman-Nielsen, Thomas; Christiansen, Anders V.

    2015-01-01

    With permafrost thawing and changes in active layer dynamics induced by climate change, interactions between biogeochemical and thermal processes in the ground are of great importance. Here, active layer dynamics have been monitored using direct current (DC) resistivity and induced polarization (IP...... and subsurface temperatures supplemented the DC-IP measurements. A time-lapse DC-IP monitoring system has been acquiring at least six datasets per day on a 42-electrode profile with 0.5. m electrode spacing since July 2013. Remote control of the data acquisition system enables interactive adaptation...... of the measurement schedule, which is critically important to acquire data in the winter months, where extremely high contact resistances increase the demands on the resistivity meter. Data acquired during the freezing period of October 2013 to February 2014 clearly image the soil freezing as a strong increase...

  18. Saturn's rings - high resolution

    Science.gov (United States)

    1981-01-01

    Voyager 2 obtained this high-resolution picture of Saturn's rings Aug. 22, when the spacecraft was 4 million kilometers (2.5 million miles) away. Evident here are the numerous 'spoke' features, in the B-ring; their very sharp, narrow appearance suggests short formation times. Scientists think electromagnetic forces are responsible in some way for these features, but no detailed theory has been worked out. Pictures such as this and analyses of Voyager 2's spoke movies may reveal more clues about the origins of these complex structures. The Voyager project is managed for NASA by the Jet Propulsion Laboratory, Pasadena, Calif.

  19. High Resolution Laboratory Spectroscopy

    CERN Document Server

    Brünken, Sandra

    2016-01-01

    In this short review we will highlight some of the recent advancements in the field of high-resolution laboratory spectroscopy that meet the needs dictated by the advent of highly sensitive and broadband telescopes like ALMA and SOFIA. Among these is the development of broadband techniques for the study of complex organic molecules, like fast scanning conventional absorption spectroscopy based on multiplier chains, chirped pulse instrumentation, or the use of synchrotron facilities. Of similar importance is the extension of the accessible frequency range to THz frequencies, where many light hydrides have their ground state rotational transitions. Another key experimental challenge is the production of sufficiently high number densities of refractory and transient species in the laboratory, where discharges have proven to be efficient sources that can also be coupled to molecular jets. For ionic molecular species sensitive action spectroscopic schemes have recently been developed to overcome some of the limita...

  20. High Time Resolution Astrophysics

    CERN Document Server

    Phelan, Don; Shearer, Andrew

    2008-01-01

    High Time Resolution Astrophysics (HTRA) is an important new window to the universe and a vital tool in understanding a range of phenomena from diverse objects and radiative processes. This importance is demonstrated in this volume with the description of a number of topics in astrophysics, including quantum optics, cataclysmic variables, pulsars, X-ray binaries and stellar pulsations to name a few. Underlining this science foundation, technological developments in both instrumentation and detectors are described. These instruments and detectors combined cover a wide range of timescales and can measure fluxes, spectra and polarisation. These advances make it possible for HTRA to make a big contribution to our understanding of the Universe in the next decade.

  1. Current challenges for high-resolution monitoring of deep geological repository boreholes using terrestrial laser scanner and photogrammetry

    Science.gov (United States)

    Carrea, Dario; Savunen, Johanna; Abellan, Antonio; Derron, Marc-Henri; Mattila, Jussi; Jaboyedoff, Michel

    2015-04-01

    The Onkalo site has been selected as final deep geological repository for the disposal of nuclear waste in Finland. Several exploratory boreholes, similar to those that will host the nuclear waste, are currently under construction in order to analyse various technical aspects of the disposal. Among them, an accurate monitoring of the deformation of each borehole is required. The present study aims at finding the most suitable technique for measuring and monitoring small scale (below mm) deformations of these boreholes with high confidence and accuracy. Two different close-range monitoring techniques are compared here: a phase-shift terrestrial laser scanning (Z+F 5006i) and photogrammetry (Canon EOS 6D&EF20mm + Adamtech 3DM Mine Mapping Suite 2.5). Both techniques are applied using multi temporal acquisitions. As for the data acquired by the terrestrial laser scanner, our study has revealed that parts of the 3D datasets are affected by an artificial distortion, with a maximum shift up to 6 mm, which is clearly below the required accuracy. The origin of this artifact is related with the data acquisition strategy: since the accuracy of the laser measurement is affected by the incidence angle, we observed that when the incidence angle is higher than 45°, the range is unsatisfactorily underestimated. Furthermore, we found another issue in the influence of the surface condition on range measurement, such as wet versus dry, or dark versus light colored rock surface. As for the photogrammetric data, we observed that, when compared to a theoretical cylinder, the 3D point cloud was affected by a sub-millimetric distortion. This distortion is due to the construction and georeferencing of the final 3D model. The error can reach up to +/- 0.8 mm in the border areas of the picture, which is significant value as a millimetric deformation should be detected. Up to now, the photogrammetric acquisitions have provided more accurate results than the laser scanning, but there is a

  2. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  3. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  4. Direct current (DC) resistivity and Induced Polarization (IP) monitoring of active layer dynamics at high temporal resolution

    DEFF Research Database (Denmark)

    Doetsch, J.; Fiandaca, G.; Ingeman-Nielsen, Thomas;

    2015-01-01

    With permafrost thawing and changes in active layer dynamics induced by climate change, interactions between biogeochemical and thermal processes in the ground are of great importance. Here, active layer dynamics have been monitored using direct current (DC) resistivity and induced polarization (IP...... the soil freezing as a strong increase in resistivity. While the freezing horizon generally moves deeper with time, some variations in the freezing depth are observed along the profile. Comparison with depth-specific soil temperature indicates an exponential relationship between resistivity and below...

  5. High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

    Science.gov (United States)

    Gregori, Josep; Rodríguez-Frias, Francisco; Buti, Maria; Madejon, Antonio; Perez-del-Pulgar, Sofia; Garcia-Cehic, Damir; Casillas, Rosario; Blasi, Maria; Homs, Maria; Tabernero, David; Alvarez-Tejado, Miguel; Muñoz, Jose Manuel; Cubero, Maria; Caballero, Andrea; delCampo, Jose Antonio; Domingo, Esteban; Belmonte, Irene; Nieto, Leonardo; Lens, Sabela; Muñoz-de-Rueda, Paloma; Sanz-Cameno, Paloma; Sauleda, Silvia; Bes, Marta; Gomez, Jordi; Briones, Carlos; Perales, Celia; Sheldon, Julie; Castells, Lluis; Viladomiu, Lluis; Salmeron, Javier; Ruiz-Extremera, Angela; Quiles-Pérez, Rosa; Moreno-Otero, Ricardo; López-Rodríguez, Rosario; Allende, Helena; Romero-Gómez, Manuel; Guardia, Jaume; Esteban, Rafael; Garcia-Samaniego, Javier; Forns, Xavier

    2014-01-01

    Hepatitis C virus (HCV) is classified into seven major genotypes and 67 subtypes. Recent studies have shown that in HCV genotype 1-infected patients, response rates to regimens containing direct-acting antivirals (DAAs) are subtype dependent. Currently available genotyping methods have limited subtyping accuracy. We have evaluated the performance of a deep-sequencing-based HCV subtyping assay, developed for the 454/GS-Junior platform, in comparison with those of two commercial assays (Versant HCV genotype 2.0 and Abbott Real-time HCV Genotype II) and using direct NS5B sequencing as a gold standard (direct sequencing), in 114 clinical specimens previously tested by first-generation hybridization assay (82 genotype 1 and 32 with uninterpretable results). Phylogenetic analysis of deep-sequencing reads matched subtype 1 calling by population Sanger sequencing (69% 1b, 31% 1a) in 81 specimens and identified a mixed-subtype infection (1b/3a/1a) in one sample. Similarly, among the 32 previously indeterminate specimens, identical genotype and subtype results were obtained by direct and deep sequencing in all but four samples with dual infection. In contrast, both Versant HCV Genotype 2.0 and Abbott Real-time HCV Genotype II failed subtype 1 calling in 13 (16%) samples each and were unable to identify the HCV genotype and/or subtype in more than half of the non-genotype 1 samples. We concluded that deep sequencing is more efficient for HCV subtyping than currently available methods and allows qualitative identification of mixed infections and may be more helpful with respect to informing treatment strategies with new DAA-containing regimens across all HCV subtypes. PMID:25378574

  6. High Resolution Formaldehyde Photochemistry

    Science.gov (United States)

    Ernest, C. T.; Bauer, D.; Hynes, A. J.

    2010-12-01

    Formaldehyde (HCHO) is the most abundant and most important organic carbonyl compound in the atmosphere. The sources of formaldehyde are the oxidation of methane, isoprene, acetone, and other volatile organic compounds (VOCs); fossil fuel combustion; and biomass burning. The dominant loss mechanism for formaldehyde is photolysis which occurs via two pathways: (R1) HCHO + hv → HCO + H (R2) HCHO + hv → H2 + CO The first pathway (R1) is referred to as the radical channel, while the second pathway (R2) is referred to as the molecular channel. The products of both pathways play a significant role in atmospheric chemistry. The CO that is produced in the molecular channel undergoes further oxidation to produce CO2. Under atmospheric conditions, the H atom and formyl radical that are produced in the radical channel undergo rapid reactions with O2 to produce the hydroperoxyl radical (HO2) via (R3) and (R4). (R3) HCO + O2 → HO2 + CO (R4) H + O2 → HO2 Thus, for every photon absorbed, the photolysis of formaldehyde can contribute one CO2 molecule to the global greenhouse budget or two HO2 radicals to the tropospheric HOx (OH + HO2) cycle. The HO2 radicals produced during formaldehyde photolysis have also been implicated in the formation of photochemical smog. The HO2 radicals act as radical chain carriers and convert NO to NO2, which ultimately results in the catalytic production of O3. Constraining the yield of HO2 produced via HCHO photolysis is essential for improving tropospheric chemistry models. In this study, both the absorption cross section and the quantum yield of the radical channel (R1) were measured at high resolution over the tropospherically relevant wavelength range 304-330 nm. For the cross section measurements a narrow linewidth Nd:YAG pumped dye laser was used with a multi-pass cell. Partial pressures of HCHO were kept below 0.3 torr. Simultaneous measurement of OH LIF in a flame allowed absolute calibration of the wavelength scale. Pressure

  7. High-resolution land topography

    Science.gov (United States)

    Massonnet, Didier; Elachi, Charles

    2006-11-01

    After a description of the background, methods of production and some scientific uses of high-resolution land topography, we present the current status and the prospect of radar interferometry, regarded as one of the best techniques for obtaining the most global and the most accurate topographic maps. After introducing briefly the theoretical aspects of radar interferometry - principles, limits of operation and various capabilities -, we will focus on the topographic applications that resulted in an almost global topographic map of the earth: the SRTM map. After introducing the Interferometric Cartwheel system, we will build on its expected performances to discuss the scientific prospects of refining a global topographic map to sub-metric accuracy. We also show how other fields of sciences such as hydrology may benefit from the products generated by interferometric radar systems. To cite this article: D. Massonnet, C. Elachi, C. R. Geoscience 338 (2006).

  8. High PRF high current switch

    Science.gov (United States)

    Moran, Stuart L.; Hutcherson, R. Kenneth

    1990-03-27

    A triggerable, high voltage, high current, spark gap switch for use in pu power systems. The device comprises a pair of electrodes in a high pressure hydrogen environment that is triggered by introducing an arc between one electrode and a trigger pin. Unusually high repetition rates may be obtained by undervolting the switch, i.e., operating the trigger at voltages much below the self-breakdown voltage of the device.

  9. High resolution digital delay timer

    Science.gov (United States)

    Martin, Albert D.

    1988-01-01

    Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay (20) provides a first output signal (24) at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits (26, 28) latch the high resolution data (24) to form a first synchronizing data set (60). A selected time interval has been preset to internal counters (142, 146, 154) and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses (32, 34) count down the counters to generate an internal pulse delayed by an interval which is functionally related to the preset time interval. A second LCD (184) corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD (74) to generate a second set of synchronizing data (76) which is complementary with the first set of synchronizing data (60) for presentation to logic circuits (64). The logic circuits (64) further delay the internal output signal (72) to obtain a proper phase relationship of an output signal (80) with the internal pulses (32, 34). The final delayed output signal (80) thereafter enables the output pulse generator (82) to produce the desired output pulse (84) at the preset time delay interval following input of the trigger pulse (10, 12).

  10. High Resolution Orientation Imaging Microscopy

    Science.gov (United States)

    2012-05-02

    carbon distribution as it relates to the presence of Bainite phase (with small tetragonality) interspersed among the cubic ferrite. An example of the...preferentially segregate. The view offered by these high resolution methods differs from what has been considered before: grains thought to be Bainite

  11. High-Resolution Instrumentation Radar.

    Science.gov (United States)

    1986-09-30

    30 September 1986 Los Angeles Air Force Station 13. NUMBER OF PAGES Los Angeles, Calif. 90009-2960 36 74. MONITORING AGENCY NAME & ADDRESS(If...TREE PLMUT ",-20 -CUTLIASS DumpER SED AN... TREE TRUNK, -0 - MERC BUMPER f - 40 H!-I -50 iI Fig. 7. High-Resolution Instrumentation Radar View of

  12. Simulation of synoptic and sub-synoptic phenomena over East Africa and Arabian Peninsula for current and future climate using a high resolution AGCM

    Science.gov (United States)

    Raj, Jerry; Kunhu Bangalath, Hamza; Stenchikov, Georgiy

    2015-04-01

    Climate regimes of East Africa and Arabia are complex and are poorly understood. East Africa has large-scale tropical controls like major convergence zones and air streams. The region is in the proximity of two monsoons, north-east and south-west, and the humid and thermally unstable Congo air stream. The domain comprises regions with one, two, and three rainfall maxima, and the rainfall pattern over this region has high spatial variability. To explore the synoptic and sub-synoptic phenomena that drive the climate of the region we conducted climate simulations using a high resolution Atmospheric General Circulation Model (AGCM), GFDL's High Resolution Atmospheric Model (HiRAM). Historic simulations (1975-2004) and future projections (2007-2050), with both RCP 4.5 and RCP 8.5 pathways, were performed according to CORDEX standard. The sea surface temperature (SST) was prescribed from the 2°x2.5° latitude-longitude resolution GFDL Earth System Model runs of IPCC AR5, as bottom boundary condition over the ocean. Our simulations were conducted at a horizontal grid spacing of 25 km, which is an ample resolution for regional climate simulation. In comparison with the regional models, global HiRAM has the advantage of accounting for two-way interaction between regional and global scale processes. Our initial results show that HiRAM simulations for historic period well reproduce the regional climate in East Africa and the Arabian Peninsula with their complex interplay of regional and global processes. Our future projections indicate warming and increased precipitation over the Ethiopian highlands and the Greater Horn of Africa. We found significant regional differences between RCP 4.5 and RCP 8.5 projections, e.g., west coast of the Arabian Peninsula, show anomalies of opposite signs in these two simulations.

  13. Simulation of synoptic and sub-synoptic phenomena over East Africa and Arabian Peninsula for current and future climate using a high resolution AGCM

    KAUST Repository

    Raj, Jerry

    2015-04-01

    Climate regimes of East Africa and Arabia are complex and are poorly understood. East Africa has large-scale tropical controls like major convergence zones and air streams. The region is in the proximity of two monsoons, north-east and south-west, and the humid and thermally unstable Congo air stream. The domain comprises regions with one, two, and three rainfall maxima, and the rainfall pattern over this region has high spatial variability. To explore the synoptic and sub-synoptic phenomena that drive the climate of the region we conducted climate simulations using a high resolution Atmospheric General Circulation Model (AGCM), GFDL\\'s High Resolution Atmospheric Model (HiRAM). Historic simulations (1975-2004) and future projections (2007-2050), with both RCP 4.5 and RCP 8.5 pathways, were performed according to CORDEX standard. The sea surface temperature (SST) was prescribed from the 2°x2.5° latitude-longitude resolution GFDL Earth System Model runs of IPCC AR5, as bottom boundary condition over the ocean. Our simulations were conducted at a horizontal grid spacing of 25 km, which is an ample resolution for regional climate simulation. In comparison with the regional models, global HiRAM has the advantage of accounting for two-way interaction between regional and global scale processes. Our initial results show that HiRAM simulations for historic period well reproduce the regional climate in East Africa and the Arabian Peninsula with their complex interplay of regional and global processes. Our future projections indicate warming and increased precipitation over the Ethiopian highlands and the Greater Horn of Africa. We found significant regional differences between RCP 4.5 and RCP 8.5 projections, e.g., west coast of the Arabian Peninsula, show anomalies of opposite signs in these two simulations.

  14. Requirements on high resolution detectors

    Energy Technology Data Exchange (ETDEWEB)

    Koch, A. [European Synchrotron Radiation Facility, Grenoble (France)

    1997-02-01

    For a number of microtomography applications X-ray detectors with a spatial resolution of 1 {mu}m are required. This high spatial resolution will influence and degrade other parameters of secondary importance like detective quantum efficiency (DQE), dynamic range, linearity and frame rate. This note summarizes the most important arguments, for and against those detector systems which could be considered. This article discusses the mutual dependencies between the various figures which characterize a detector, and tries to give some ideas on how to proceed in order to improve present technology.

  15. HRSC: High resolution stereo camera

    Science.gov (United States)

    Neukum, G.; Jaumann, R.; Basilevsky, A.T.; Dumke, A.; Van Gasselt, S.; Giese, B.; Hauber, E.; Head, J. W.; Heipke, C.; Hoekzema, N.; Hoffmann, H.; Greeley, R.; Gwinner, K.; Kirk, R.; Markiewicz, W.; McCord, T.B.; Michael, G.; Muller, Jan-Peter; Murray, J.B.; Oberst, J.; Pinet, P.; Pischel, R.; Roatsch, T.; Scholten, F.; Willner, K.

    2009-01-01

    The High Resolution Stereo Camera (HRSC) on Mars Express has delivered a wealth of image data, amounting to over 2.5 TB from the start of the mapping phase in January 2004 to September 2008. In that time, more than a third of Mars was covered at a resolution of 10-20 m/pixel in stereo and colour. After five years in orbit, HRSC is still in excellent shape, and it could continue to operate for many more years. HRSC has proven its ability to close the gap between the low-resolution Viking image data and the high-resolution Mars Orbiter Camera images, leading to a global picture of the geological evolution of Mars that is now much clearer than ever before. Derived highest-resolution terrain model data have closed major gaps and provided an unprecedented insight into the shape of the surface, which is paramount not only for surface analysis and geological interpretation, but also for combination with and analysis of data from other instruments, as well as in planning for future missions. This chapter presents the scientific output from data analysis and highlevel data processing, complemented by a summary of how the experiment is conducted by the HRSC team members working in geoscience, atmospheric science, photogrammetry and spectrophotometry. Many of these contributions have been or will be published in peer-reviewed journals and special issues. They form a cross-section of the scientific output, either by summarising the new geoscientific picture of Mars provided by HRSC or by detailing some of the topics of data analysis concerning photogrammetry, cartography and spectral data analysis.

  16. Section on High Resolution Optical Imaging (HROI)

    Data.gov (United States)

    Federal Laboratory Consortium — The Section on High Resolution Optical Imaging (HROI) develops novel technologies for studying biological processes at unprecedented speed and resolution. Research...

  17. Customized MFM probes with high lateral resolution

    Directory of Open Access Journals (Sweden)

    Óscar Iglesias-Freire

    2016-07-01

    Full Text Available Magnetic force microscopy (MFM is a widely used technique for magnetic imaging. Besides its advantages such as the high spatial resolution and the easy use in the characterization of relevant applied materials, the main handicaps of the technique are the lack of control over the tip stray field and poor lateral resolution when working under standard conditions. In this work, we present a convenient route to prepare high-performance MFM probes with sub-10 nm (sub-25 nm topographic (magnetic lateral resolution by following an easy and quick low-cost approach. This allows one to not only customize the tip stray field, avoiding tip-induced changes in the sample magnetization, but also to optimize MFM imaging in vacuum (or liquid media by choosing tips mounted on hard (or soft cantilevers, a technology that is currently not available on the market.

  18. Evaluation of the impact of the 2010 pyroclastic density currents at Merapi volcano from high-resolution satellite imagery, field investigations and numerical simulations

    Science.gov (United States)

    Charbonnier, S. J.; Germa, A.; Connor, C. B.; Gertisser, R.; Preece, K.; Komorowski, J.-C.; Lavigne, F.; Dixon, T.; Connor, L.

    2013-07-01

    The 2010 pyroclastic density currents (PDC) at Merapi have presented a rare opportunity to collect a uniquely detailed dataset of the source, extent, lateral variations and impact of various PDC deposits on a densely populated area. Using traditional volcanological field-based methods and a multi-temporal dataset of high-resolution satellite imagery, a total of 23 PDC events have been recognized, including 5 main channeled flows, 15 overbank flows derived from overspill and re-channelization of the main PDCs into adjacent tributaries and two main surge events. The 2010 PDC deposits covered an area of ~ 22.3 km2, unequally distributed between valley-filling (6.9%), overbank (22.4%) and surge and associated fallout deposits (71.7%). Their total estimated non-DRE volume is ~ 36.3 × 106 m3, with 50.2% of this volume accounting for valley-filling deposits, 39.3% for overbank deposits and 10.5% for surge and associated fallout deposits. More than 70% of the total volume was deposited during the third eruptive phase (4-5 November), and only 16.6%, 11.5% and 0.9% during the first (26-29 October), second (30 October - 3 November) and fourth phase (6-23 November), respectively. The internal architecture and lithofacies variations of the 2010 PDC deposits were investigated using data collected from 30 stratigraphic sections measured after one rainy season of erosion. The results show that complex, local-scale variations in flow dynamics and deposit architectures are apparent and that the major factors controlling the propagation of the main flows and their potential hazards for overbanking were driven by: (1) the rapid emplacement of several voluminous PDCs, associated with the steady infilling of the receiving landscape after the two first phases of the eruption; (2) longitudinal changes in channel capacity following increased sinuosity in the valley and decreased containment space; and (3) the effects of varying source mechanisms (gravitational dome collapse, vertical or

  19. High-resolution three-dimensional imaging of a depleted CMOS sensor using an edge Transient Current Technique based on the Two Photon Absorption process (TPA-eTCT)

    CERN Document Server

    García, Marcos Fernández; Echeverría, Richard Jaramillo; Moll, Michael; Santos, Raúl Montero; Moya, David; Pinto, Rogelio Palomo; Vila, Iván

    2016-01-01

    For the first time, the deep n-well (DNW) depletion space of a High Voltage CMOS sensor has been characterized using a Transient Current Technique based on the simultaneous absorption of two photons. This novel approach has allowed to resolve the DNW implant boundaries and therefore to accurately determine the real depleted volume and the effective doping concentration of the substrate. The unprecedented spatial resolution of this new method comes from the fact that measurable free carrier generation in two photon mode only occurs in a micrometric scale voxel around the focus of the beam. Real three-dimensional spatial resolution is achieved by scanning the beam focus within the sample.

  20. High-resolution intravital microscopy.

    Directory of Open Access Journals (Sweden)

    Volker Andresen

    Full Text Available Cellular communication constitutes a fundamental mechanism of life, for instance by permitting transfer of information through synapses in the nervous system and by leading to activation of cells during the course of immune responses. Monitoring cell-cell interactions within living adult organisms is crucial in order to draw conclusions on their behavior with respect to the fate of cells, tissues and organs. Until now, there is no technology available that enables dynamic imaging deep within the tissue of living adult organisms at sub-cellular resolution, i.e. detection at the level of few protein molecules. Here we present a novel approach called multi-beam striped-illumination which applies for the first time the principle and advantages of structured-illumination, spatial modulation of the excitation pattern, to laser-scanning-microscopy. We use this approach in two-photon-microscopy--the most adequate optical deep-tissue imaging-technique. As compared to standard two-photon-microscopy, it achieves significant contrast enhancement and up to 3-fold improved axial resolution (optical sectioning while photobleaching, photodamage and acquisition speed are similar. Its imaging depth is comparable to multifocal two-photon-microscopy and only slightly less than in standard single-beam two-photon-microscopy. Precisely, our studies within mouse lymph nodes demonstrated 216% improved axial and 23% improved lateral resolutions at a depth of 80 µm below the surface. Thus, we are for the first time able to visualize the dynamic interactions between B cells and immune complex deposits on follicular dendritic cells within germinal centers (GCs of live mice. These interactions play a decisive role in the process of clonal selection, leading to affinity maturation of the humoral immune response. This novel high-resolution intravital microscopy method has a huge potential for numerous applications in neurosciences, immunology, cancer research and

  1. High-resolution image analysis.

    Science.gov (United States)

    Preston, K

    1986-01-01

    In many departments of cytology, cytogenetics, hematology, and pathology, research projects using high-resolution computerized microscopy are now being mounted for computation of morphometric measurements on various structural components, as well as for determination of cellular DNA content. The majority of these measurements are made in a partially automated, computer-assisted mode, wherein there is strong interaction between the user and the computerized microscope. At the same time, full automation has been accomplished for both sample preparation and sample examination for clinical determination of the white blood cell differential count. At the time of writing, approximately 1,000 robot differential counting microscopes are in the field, analyzing images of human white blood cells, red blood cells, and platelets at the overall rate of about 100,000 slides per day. This mammoth through-put represents a major accomplishment in the application of machine vision to automated microscopy for hematology. In other areas of automated high-resolution microscopy, such as cytology and cytogenetics, no commercial instruments are available (although a few metaphase-finding machines are available and other new machines have been announced during the past year). This is a disappointing product, considering the nearly half century of research effort in these areas. This paper provides examples of the state of the art in automation of cell analysis for blood smears, cervical smears, and chromosome preparations. Also treated are new developments in multi-resolution automated microscopy, where images are now being generated and analyzed by a single machine over a range of 64:1 magnification and from 10,000 X 20,000 to 500 X 500 in total picture elements (pixels). Examples of images of human lymph node and liver tissue are presented. Semi-automated systems are not treated, although there is mention of recent research in the automation of tissue analysis.

  2. High-Resolution Mass Spectrometers

    Science.gov (United States)

    Marshall, Alan G.; Hendrickson, Christopher L.

    2008-07-01

    Over the past decade, mass spectrometry has been revolutionized by access to instruments of increasingly high mass-resolving power. For small molecules up to ˜400 Da (e.g., drugs, metabolites, and various natural organic mixtures ranging from foods to petroleum), it is possible to determine elemental compositions (CcHhNnOoSsPp…) of thousands of chemical components simultaneously from accurate mass measurements (the same can be done up to 1000 Da if additional information is included). At higher mass, it becomes possible to identify proteins (including posttranslational modifications) from proteolytic peptides, as well as lipids, glycoconjugates, and other biological components. At even higher mass (˜100,000 Da or higher), it is possible to characterize posttranslational modifications of intact proteins and to map the binding surfaces of large biomolecule complexes. Here we review the principles and techniques of the highest-resolution analytical mass spectrometers (time-of-flight and Fourier transform ion cyclotron resonance and orbitrap mass analyzers) and describe some representative high-resolution applications.

  3. Ultra-high resolution AMOLED

    Science.gov (United States)

    Wacyk, Ihor; Prache, Olivier; Ghosh, Amal

    2011-06-01

    AMOLED microdisplays continue to show improvement in resolution and optical performance, enhancing their appeal for a broad range of near-eye applications such as night vision, simulation and training, situational awareness, augmented reality, medical imaging, and mobile video entertainment and gaming. eMagin's latest development of an HDTV+ resolution technology integrates an OLED pixel of 3.2 × 9.6 microns in size on a 0.18 micron CMOS backplane to deliver significant new functionality as well as the capability to implement a 1920×1200 microdisplay in a 0.86" diagonal area. In addition to the conventional matrix addressing circuitry, the HDTV+ display includes a very lowpower, low-voltage-differential-signaling (LVDS) serialized interface to minimize cable and connector size as well as electromagnetic emissions (EMI), an on-chip set of look-up-tables for digital gamma correction, and a novel pulsewidth- modulation (PWM) scheme that together with the standard analog control provides a total dimming range of 0.05cd/m2 to 2000cd/m2 in the monochrome version. The PWM function also enables an impulse drive mode of operation that significantly reduces motion artifacts in high speed scene changes. An internal 10-bit DAC ensures that a full 256 gamma-corrected gray levels are available across the entire dimming range, resulting in a measured dynamic range exceeding 20-bits. This device has been successfully tested for operation at frame rates ranging from 30Hz up to 85Hz. This paper describes the operational features and detailed optical and electrical test results for the new AMOLED WUXGA resolution microdisplay.

  4. High Speed and High Resolution Table-Top Nanoscale Imaging

    CERN Document Server

    Tadesse, G K; Demmler, S; HÄdrich, S; Wahyutama, I; Steinert, M; Spielmann, C; ZÜrch, M; TÜnnermann, A; Limpert, J; Rothhardt, J

    2016-01-01

    We present a table-top coherent diffraction imaging (CDI) experiment based on high-order harmonics generated at 18 nm by a high average power femtosecond fiber laser system. The high photon flux, narrow spectral bandwidth and high degree of spatial coherence allow for ultra-high sub-wavelength resolution imaging at a high numerical aperture. Our experiments demonstrate a half-pitch resolution of 13.6 nm, very close to the actual Abbe-limit of 12.4 nm, which is the highest resolution achieved from any table-top XUV or X-ray microscope. In addition, 20.5 nm resolution was achieved with only 3 sec of integration time bringing live diffraction imaging and 3D tomography on the nanoscale one step closer to reality. The current resolution is solely limited by the wavelength and the detector size. Thus, table-top nanoscopes with only a few-nm resolutions are in reach and will find applications in many areas of science and technology.

  5. High-resolution slug testing.

    Science.gov (United States)

    Zemansky, G M; McElwee, C D

    2005-01-01

    The hydraulic conductivity (K) variation has important ramifications for ground water flow and the transport of contaminants in ground water. The delineation of the nature of that variation can be critical to complete characterization of a site and the planning of effective and efficient remedial measures. Site-specific features (such as high-conductivity zones) need to be quantified. Our alluvial field site in the Kansas River valley exhibits spatial variability, very high conductivities, and nonlinear behavior for slug tests in the sand and gravel aquifer. High-resolution, multilevel slug tests have been performed in a number of wells that are fully screened. A general nonlinear model based on the Navier-Stokes equation, nonlinear frictional loss, non-Darcian flow, acceleration effects, radius changes in the wellbore, and a Hvorslev model for the aquifer has been used to analyze the data, employing an automated processing system that runs within the Excel spreadsheet program. It is concluded that slug tests can provide the necessary data to identify the nature of both horizontal and vertical K variation in an aquifer and that improved delineation or higher resolution of K structure is possible with shorter test intervals. The gradation into zones of higher conductivity is sharper than seen previously, and the maximum conductivity observed is greater than previously measured. However, data from this project indicate that well development, the presence of fines, and the antecedent history of the well are important interrelated factors in regard to slug-test response and can prevent obtaining consistent results in some cases.

  6. GHRSST L3C global sub-skin Sea Surface Temperature from the Advanced Very High Resolution Radiometer (AVHRR) on Metop satellites (currently Metop-B) (GDS V2) produced by OSI SAF (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A global Group for High Resolution Sea Surface Temperature (GHRSST) Level 3 Collated (L3C) dataset derived from the Advanced Very High Resolution Radiometer (AVHRR)...

  7. GHRSST L3C global sub-skin Sea Surface Temperature from the Advanced Very High Resolution Radiometer (AVHRR) on Metop satellites (currently Metop-A) (GDS V2) produced by OSI SAF (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A global Group for High Resolution Sea Surface Temperature (GHRSST) Level 3 Collated (L3C) dataset derived from the Advanced Very High Resolution Radiometer (AVHRR)...

  8. High resolution emission tomography; Tomographie d`emission haute resolution

    Energy Technology Data Exchange (ETDEWEB)

    Charon, Y.; Laniece, P.; Mastrippolito, R.; Pinot, L.; Ploux, L.; Valda Ochoa, A.; Valentin, L. [Groupe I.P.B., Experimental Research Division, Inst. de Physique Nucleaire, Paris-11 Univ., 91 - Orsay (France)

    1999-11-01

    We have developed an original high resolution tomograph for in-vivo small animal imaging. A first prototype is under evaluation. Initial results of its characterisation are presented. (authors) 3 figs.

  9. Digital interface for high-resolution displays

    Science.gov (United States)

    Hermann, David J.; Gorenflo, Ronald L.

    1999-08-01

    Commercial display interfaces are currently transitioning from analog to digital. Although this transition is in the very early stages, the military needs to begin planning their own transition to digital. There are many problems with the analog interface in high-resolution display systems that are solved by changing to a digital interface. Also, display system cost can be lower with a digital interface to a high resolution display. Battelle is under contract with DARPA to develop an advanced Display Interface (ADI) to replace the analog RGB interfaces currently used in high definition workstation displays. The goal is to create a standard digital display interface for military applications that is based on emerging commercial standards. Support for military application- specific functionality is addressed, including display test and control. The main challenges to implementing a digital display interface are described, along with approaches to address the problems. Conceptual ADI architectures are described and contrasted. The current and emerging commercial standards for digital display interfaces are reviewed in detail. Finally, the tasks required to complete the ADI effort are outlined and described.

  10. VT Hydrography Dataset - High Resolution NHD

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Vermont Hydrography Dataset (VHD) is compliant with the local resolution (also known as High Resolution) National Hydrography Dataset (NHD)...

  11. High-resolution infrared imaging

    Science.gov (United States)

    Falco, Charles M.

    2010-08-01

    The hands and mind of an artist are intimately involved in the creative process of image formation, intrinsically making paintings significantly more complex than photographs to analyze. In spite of this difficulty, several years ago the artist David Hockney and I identified optical evidence within a number of paintings that demonstrated artists began using optical projections as early as c1425 - nearly 175 years before Galileo - as aids for producing portions of their images. In the course of our work, Hockney and I developed insights that I have been applying to a new approach to computerized image analysis. Recently I developed and characterized a portable high resolution infrared for capturing additional information from paintings. Because many pigments are semi-transparent in the IR, in a number of cases IR photographs ("reflectograms") have revealed marks made by the artists that had been hidden under paint ever since they were made. I have used this IR camera to capture photographs ("reflectograms") of hundreds of paintings in over a dozen museums on three continents and, in some cases, these reflectograms have provided new insights into decisions the artists made in creating the final images that we see in the visible.

  12. Fast Backprojection Techniques for High Resolution Tomography

    CERN Document Server

    Koshev, Nikolay; Miqueles, Eduardo X

    2016-01-01

    Fast image reconstruction techniques are becoming important with the increasing number of scientific cases in high resolution micro and nano tomography. The processing of the large scale three-dimensional data demands new mathematical tools for the tomographic reconstruction task because of the big computational complexity of most current algorithms as the sizes of tomographic data grow with the development of more powerful acquisition hardware and more refined scientific needs. In the present paper we propose a new fast back-projection operator for the processing of tomographic data and compare it against other fast reconstruction techniques.

  13. High-resolution neutron tomography

    Energy Technology Data Exchange (ETDEWEB)

    Mikerov, V.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Zhitnik, I.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Ignat`ev, A.P. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Isakov, A.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Korneev, V.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Krutov, V.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Kuzin, S.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Oparin, S.N. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Pertsov, A.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Podolyak, E.R. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Sobel`man, I.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Tindo, I.P. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Tukarev, B.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation)

    1995-12-31

    A neutron tomography technique with a coordinate resolution of several tens of micrometers has been developed. Our results indicate that the technique resolves details with dimensions less than 100 {mu}m and measures a linear attenuation of less than {approx} 0.1 cm{sup -1}. Tomograms can be reconstructed using incomplete data. Limits on the resolution of the restored pattern are analyzed, and ways to improve the sensitivity of the technique are discussed. (orig.).

  14. Separating spin torque and heating effects in current-induced domain wall motion probed by high-resolution transmission electron microscopy

    DEFF Research Database (Denmark)

    Junginger, F.; Klaeui, M.; Backes, D.

    2007-01-01

    Observations of domain wall motion and transformations due to injected current pulses in permalloy zigzag structures using off-axis electron holography and Lorentz microscopy are reported. Heating on membranes leads to thermally activated random behavior at low current densities and by backcoating...

  15. Influence of total beam current on HRTEM image resolution in differentially pumped ETEM with nitrogen gas.

    Science.gov (United States)

    Bright, A N; Yoshida, K; Tanaka, N

    2013-01-01

    Environmental transmission electron microscopy (ETEM) enables the study of catalytic and other reaction processes as they occur with Angstrom-level resolution. The microscope used is a dedicated ETEM (Titan ETEM, FEI Company) with a differential pumping vacuum system and apertures, allowing aberration corrected high-resolution transmission electron microscopy (HRTEM) imaging to be performed with gas pressures up to 20 mbar in the sample area and with significant advantages over membrane-type E-cell holders. The effect on image resolution of varying the nitrogen gas pressure, electron beam current density and total beam current were measured using information limit (Young's fringes) on a standard cross grating sample and from silicon crystal lattice imaging. As expected, increasing gas pressure causes a decrease in HRTEM image resolution. However, the total electron beam current also causes big changes in the image resolution (lower beam current giving better resolution), whereas varying the beam current density has almost no effect on resolution, a result that has not been reported previously. This behavior is seen even with zero-loss filtered imaging, which we believe shows that the drop in resolution is caused by elastic scattering at gas ions created by the incident electron beam. Suitable conditions for acquiring high resolution images in a gas environment are discussed. Lattice images at nitrogen pressures up to 16 mbar are shown, with 0.12 nm information transfer at 4 mbar.

  16. High speed, high current pulsed driver circuit

    Energy Technology Data Exchange (ETDEWEB)

    Carlen, Christopher R.

    2017-03-21

    Various technologies presented herein relate to driving a LED such that the LED emits short duration pulses of light. This is accomplished by driving the LED with short duration, high amplitude current pulses. When the LED is driven by short duration, high amplitude current pulses, the LED emits light at a greater amplitude compared to when the LED is driven by continuous wave current.

  17. High-resolution electron microscopy

    CERN Document Server

    Spence, John C H

    2013-01-01

    This new fourth edition of the standard text on atomic-resolution transmission electron microscopy (TEM) retains previous material on the fundamentals of electron optics and aberration correction, linear imaging theory (including wave aberrations to fifth order) with partial coherence, and multiple-scattering theory. Also preserved are updated earlier sections on practical methods, with detailed step-by-step accounts of the procedures needed to obtain the highest quality images of atoms and molecules using a modern TEM or STEM electron microscope. Applications sections have been updated - these include the semiconductor industry, superconductor research, solid state chemistry and nanoscience, and metallurgy, mineralogy, condensed matter physics, materials science and material on cryo-electron microscopy for structural biology. New or expanded sections have been added on electron holography, aberration correction, field-emission guns, imaging filters, super-resolution methods, Ptychography, Ronchigrams, tomogr...

  18. DESIR high resolution separator at GANIL, France

    Directory of Open Access Journals (Sweden)

    Toprek Dragan

    2012-01-01

    Full Text Available A high-resolution separator for the SPIRAL2/DESIR project at GANIL has been designed. The extracted isotopes from SPIRAL2 will be transported to and cooled in a RFQ cooler yielding beams with very low transverse emittance and energy spread. These beams will then be accelerated to 60 keV and sent to a high-resolution mass separator where a specific isotope will be selected. The good beam properties extracted from the RFQ cooler will allow one to obtain a mass resolution of č26000 with the high-resolution mass separator.

  19. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal describes a plan to build a prototype small stroke, high precision deformable mirror suitable for space-based operation in systems for high-resolution...

  20. High resolution imaging detectors and applications

    CERN Document Server

    Saha, Swapan K

    2015-01-01

    Interferometric observations need snapshots of very high time resolution of the order of (i) frame integration of about 100 Hz or (ii) photon-recording rates of several megahertz (MHz). Detectors play a key role in astronomical observations, and since the explanation of the photoelectric effect by Albert Einstein, the technology has evolved rather fast. The present-day technology has made it possible to develop large-format complementary metal oxide–semiconductor (CMOS) and charge-coupled device (CCD) array mosaics, orthogonal transfer CCDs, electron-multiplication CCDs, electron-avalanche photodiode arrays, and quantum-well infrared (IR) photon detectors. The requirements to develop artifact-free photon shot noise-limited images are higher sensitivity and quantum efficiency, reduced noise that includes dark current, read-out and amplifier noise, smaller point-spread functions, and higher spectral bandwidth. This book aims to address such systems, technologies and design, evaluation and calibration, control...

  1. High-Resolution Movement EEG Classification

    Directory of Open Access Journals (Sweden)

    Jakub Štastný

    2007-01-01

    Full Text Available The aim of the contribution is to analyze possibilities of high-resolution movement classification using human EEG. For this purpose, a database of the EEG recorded during right-thumb and little-finger fast flexion movements of the experimental subjects was created. The statistical analysis of the EEG was done on the subject's basis instead of the commonly used grand averaging. Statistically significant differences between the EEG accompanying movements of both fingers were found, extending the results of other so far published works. The classifier based on hidden Markov models was able to distinguish between movement and resting states (classification score of 94–100%, but it was unable to recognize the type of the movement. This is caused by the large fraction of other (nonmovement related EEG activities in the recorded signals. A classification method based on advanced EEG signal denoising is being currently developed to overcome this problem.

  2. High-Resolution Data for a Low-Resolution World

    Energy Technology Data Exchange (ETDEWEB)

    Brady, Brendan Williams [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-05-10

    In the past 15 years, the upper section of Cañon de Valle has been severely altered by wildfires and subsequent runoff events. Loss of root structures on high-angle slopes results in debris flow and sediment accumulation in the narrow canyon bottom. The original intent of the study described here was to better understand the changes occurring in watershed soil elevations over the course of several post-fire years. An elevation dataset from 5 years post-Cerro Grande fire was compared to high-resolution LiDAR data from 14 years post-Cerro Grande fire (also 3 years post-Las Conchas fire). The following analysis was motivated by a problematic comparison of these datasets of unlike resolution, and therefore focuses on what the data reveals of itself. The objective of this study is to highlight the effects vegetation can have on remote sensing data that intends to read ground surface elevation.

  3. A high-resolution vehicle emission inventory for China

    Science.gov (United States)

    Zheng, B.; Zhang, Q.; He, K.; Huo, H.; Yao, Z.; Wang, X.

    2012-12-01

    Developing high resolution emission inventory is an essential task for air quality modeling and management. However, current vehicle emission inventories in China are usually developed at provincial level and then allocated to grids based on various spatial surrogates, which is difficult to get high spatial resolution. In this work, we developed a new approach to construct a high-resolution vehicle emission inventory for China. First, vehicle population at county level were estimated by using the relationship between per-capita GDP and vehicle ownership. Then the Weather Research and Forecasting (WRF) model were used to drive the International Vehicle Emission (IVE) model to get monthly emission factors for each county. Finally, vehicle emissions by county were allocated to grids with 5-km horizon resolution by using high-resolution road network data. This work provides a better understanding of spatial representation of vehicle emissions in China and can benefit both air quality modeling and management with improved spatial accuracy.

  4. Towards optical intensity interferometry for high angular resolution stellar astrophysics

    CERN Document Server

    Nunez, Paul D

    2012-01-01

    Most neighboring stars are still detected as point sources and are beyond the angular resolution reach of current observatories. Methods to improve our understanding of stars at high angular resolution are investigated. Air Cherenkov telescopes (ACTs), primarily used for Gamma-ray astronomy, enable us to increase our understanding of the circumstellar environment of a particular system. When used as optical intensity interferometers, future ACT arrays will allow us to detect stars as extended objects and image their surfaces at high angular resolution. Optical stellar intensity interferometry (SII) with ACT arrays, composed of nearly 100 telescopes, will provide means to measure fundamental stellar parameters and also open the possibility of model-independent imaging. A data analysis algorithm is developed and permits the reconstruction of high angular resolution images from simulated SII data. The capabilities and limitations of future ACT arrays used for high angular resolution imaging are investigated via ...

  5. High Resolution Radar Measurements of Snow Avalanches

    Science.gov (United States)

    McElwaine, Jim; Sovilla, Betty; Vriend, Nathalie; Brennan, Paul; Ash, Matt; Keylock, Chris

    2013-04-01

    Geophysical mass flows, such as snow avalanches, are a major hazard in mountainous areas and have a significant impact on the infrastructure, economy and tourism of such regions. Obtaining a thorough understanding of the dynamics of snow avalanches is crucial for risk assessment and the design of defensive structures. However, because the underlying physics is poorly understood there are significant uncertainties concerning current models, which are poorly validated due to a lack of high resolution data. Direct observations of the denser core of a large avalanche are particularly difficult, since it is frequently obscured by the dilute powder cloud. We have developed and installed a phased array FMCW radar system that penetrates the powder cloud and directly images the dense core with a resolution of around 1 m at 50 Hz over the entire slope. We present data from recent avalanches at Vallee de la Sionne that show a wealth of internal structure and allow the tracking of individual fronts, roll waves and surges down the slope for the first time. We also show good agreement between the radar results and existing measurement systems that record data at particular points on the avalanche track.

  6. High resolution studies of massive primordial haloes

    CERN Document Server

    Latif, M A; Schmidt, W; Niemeyer, J

    2012-01-01

    Atomic cooling haloes with T_vir > 10^4 K are the most plausible sites for the formation of the first galaxies. In this article, we aim to study the implications of gravity driven turbulence in protogalactic haloes. By varying the resolution per Jeans length, we explore whether the turbulent cascade is resolved well enough to obtain converged results. We have performed high resolution cosmological simulations using the adaptive mesh refinement code Enzo including a subgrid-scale turbulence model to study the role of unresolved turbulence. We compared the results of three different Jeans resolutions from 16 to 64 cells. While radially averaged profiles roughly agree at different resolutions, differences in the morphology reveal that even the highest resolution employed provides no convergence. Moreover, taking into account unresolved turbulence significantly influences the morphology of a halo. We have quantified the properties of the high-density clumps in the halo. These clumps are gravitationally unbound wi...

  7. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this proposal we describe a plan to build a deformable mirror suitable for space-based operation in systems for high-resolution imaging. The prototype DM will be...

  8. High range resolution micro-Doppler analysis

    Science.gov (United States)

    Cammenga, Zachary A.; Smith, Graeme E.; Baker, Christopher J.

    2015-05-01

    This paper addresses use of the micro-Doppler effect and the use of high range-resolution profiles to observe complex targets in complex target scenes. The combination of micro-Doppler and high range-resolution provides the ability to separate the motion of complex targets from one another. This ability leads to the differentiation of targets based on their micro-Doppler signatures. Without the high-range resolution, this would not be possible because the individual signatures would not be separable. This paper also addresses the use of the micro-Doppler information and high range-resolution profiles to generate an approximation of the scattering properties of a complex target. This approximation gives insight into the structure of the complex target and, critically, is created without using a pre-determined target model.

  9. Structure of high-resolution NMR spectra

    CERN Document Server

    Corio, PL

    2012-01-01

    Structure of High-Resolution NMR Spectra provides the principles, theories, and mathematical and physical concepts of high-resolution nuclear magnetic resonance spectra.The book presents the elementary theory of magnetic resonance; the quantum mechanical theory of angular momentum; the general theory of steady state spectra; and multiple quantum transitions, double resonance and spin echo experiments.Physicists, chemists, and researchers will find the book a valuable reference text.

  10. High-resolution transcriptome of human macrophages.

    Directory of Open Access Journals (Sweden)

    Marc Beyer

    Full Text Available Macrophages are dynamic cells integrating signals from their microenvironment to develop specific functional responses. Although, microarray-based transcriptional profiling has established transcriptional reprogramming as an important mechanism for signal integration and cell function of macrophages, current knowledge on transcriptional regulation of human macrophages is far from complete. To discover novel marker genes, an area of great need particularly in human macrophage biology but also to generate a much more thorough transcriptome of human M1- and M1-like macrophages, we performed RNA sequencing (RNA-seq of human macrophages. Using this approach we can now provide a high-resolution transcriptome profile of human macrophages under classical (M1-like and alternative (M2-like polarization conditions and demonstrate a dynamic range exceeding observations obtained by previous technologies, resulting in a more comprehensive understanding of the transcriptome of human macrophages. Using this approach, we identify important gene clusters so far not appreciated by standard microarray techniques. In addition, we were able to detect differential promoter usage, alternative transcription start sites, and different coding sequences for 57 gene loci in human macrophages. Moreover, this approach led to the identification of novel M1-associated (CD120b, TLR2, SLAMF7 as well as M2-associated (CD1a, CD1b, CD93, CD226 cell surface markers. Taken together, these data support that high-resolution transcriptome profiling of human macrophages by RNA-seq leads to a better understanding of macrophage function and will form the basis for a better characterization of macrophages in human health and disease.

  11. GHRSST Level 2P sub-skin Sea Surface Temperature from the Advanced Very High Resolution Radiometer (AVHRR) on Metop satellites (currently Metop-A) (GDS V2) produced by OSI SAF (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A global 1 km Group for High Resolution Sea Surface Temperature (GHRSST) Level 2P dataset based on multi-channel sea surface temperature (SST) retrievals generated...

  12. GHRSST Level 2P sub-skin Sea Surface Temperature from the Advanced Very High Resolution Radiometer (AVHRR) on Metop satellites (currently Metop-B) (GDS V2) produced by OSI SAF (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A global 1 km Group for High Resolution Sea Surface Temperature (GHRSST) Level 2P dataset based on multi-channel sea surface temperature (SST) retrievals generated...

  13. High Resolution Surface Science at Mars

    Science.gov (United States)

    Bailey, Zachary J.; Tamppari, Leslie K.; Lock, Robert E.; Sturm, Erick J.

    2013-01-01

    The proposed mission would place a 2.4 m telescope in orbit around Mars with two focal plane instruments to obtain the highest resolution images and spectral maps of the surface to date (3-10x better than current). This investigation would make major contributions to all of the Mars Program Goals: life, climate, geology and preparation for human presence.

  14. Sensitivity study of reliable, high-throughput resolution metricsfor photoresists

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Christopher N.; Naulleau, Patrick P.

    2007-07-30

    The resolution of chemically amplified resists is becoming an increasing concern, especially for lithography in the extreme ultraviolet (EUV) regime. Large-scale screening and performance-based down-selection is currently underway to identify resist platforms that can support shrinking feature sizes. Resist screening efforts, however, are hampered by the absence of reliable resolution metrics that can objectively quantify resist resolution in a high-throughput fashion. Here we examine two high-throughput metrics for resist resolution determination. After summarizing their details and justifying their utility, we characterize the sensitivity of both metrics to two of the main experimental uncertainties associated with lithographic exposure tools, namely: limited focus control and limited knowledge of optical aberrations. For an implementation at EUV wavelengths, we report aberration and focus limited error bars in extracted resolution of {approx} 1.25 nm RMS for both metrics making them attractive candidates for future screening and down-selection efforts.

  15. High resolution SAR applications and instrument design

    Science.gov (United States)

    Dionisio, C.; Torre, A.

    1993-01-01

    The Synthetic Aperture Radar (SAR) has viewed, in the last two years, a huge increment of interest from many preset and potential users. The good spatial resolution associated to the all weather capability lead to considering SAR not only a scientific instrument but a tool for verifying and controlling the daily human relationships with the Earth Environment. New missions were identified for SAR as spatial resolution became lower than three meters: disasters, pollution, ships traffic, volcanic eruptions, earthquake effect are only a few of the possible objects which can be effectively detected, controlled and monitored by SAR mounted on satellites. High resolution radar design constraints and dimensioning are discussed.

  16. High-resolution downscaling for hydrological management

    Science.gov (United States)

    Ulbrich, Uwe; Rust, Henning; Meredith, Edmund; Kpogo-Nuwoklo, Komlan; Vagenas, Christos

    2017-04-01

    Hydrological modellers and water managers require high-resolution climate data to model regional hydrologies and how these may respond to future changes in the large-scale climate. The ability to successfully model such changes and, by extension, critical infrastructure planning is often impeded by a lack of suitable climate data. This typically takes the form of too-coarse data from climate models, which are not sufficiently detailed in either space or time to be able to support water management decisions and hydrological research. BINGO (Bringing INnovation in onGOing water management; ) aims to bridge the gap between the needs of hydrological modellers and planners, and the currently available range of climate data, with the overarching aim of providing adaptation strategies for climate change-related challenges. Producing the kilometre- and sub-daily-scale climate data needed by hydrologists through continuous simulations is generally computationally infeasible. To circumvent this hurdle, we adopt a two-pronged approach involving (1) selective dynamical downscaling and (2) conditional stochastic weather generators, with the former presented here. We take an event-based approach to downscaling in order to achieve the kilometre-scale input needed by hydrological modellers. Computational expenses are minimized by identifying extremal weather patterns for each BINGO research site in lower-resolution simulations and then only downscaling to the kilometre-scale (convection permitting) those events during which such patterns occur. Here we (1) outline the methodology behind the selection of the events, and (2) compare the modelled precipitation distribution and variability (preconditioned on the extremal weather patterns) with that found in observations.

  17. Potential High Resolution Dosimeters For MRT

    Science.gov (United States)

    Bräuer-Krisch, E.; Rosenfeld, A.; Lerch, M.; Petasecca, M.; Akselrod, M.; Sykora, J.; Bartz, J.; Ptaszkiewicz, M.; Olko, P.; Berg, A.; Wieland, M.; Doran, S.; Brochard, T.; Kamlowski, A.; Cellere, G.; Paccagnella, A.; Siegbahn, E. A.; Prezado, Y.; Martinez-Rovira, I.; Bravin, A.; Dusseau, L.; Berkvens, P.

    2010-07-01

    Microbeam Radiation Therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray microbeams of 50-600 keV, produced by 2nd and 3rd generation synchrotron sources, such as the National Synchrotron Light Source (NSLS) in the U.S., and the European Synchrotron Radiation Facility (ESRF) in France, respectively. High dose rates are necessary to deliver therapeutic doses in microscopic volumes, to avoid spreading of the microbeams by cardiosynchronous movement of the tissues. A small beam divergence and a filtered white beam spectrum in the energy range between 30 and 250 keV results in the advantage of steep dose gradients with a sharper penumbra than that produced in conventional radiotherapy. MRT research over the past 20 years has allowed a vast number of results from preclinical trials on different animal models, including mice, rats, piglets and rabbits. Microbeams in the range between 10 and 100 micron width show an unprecedented sparing of normal radiosensitive tissues as well as preferential damage to malignant tumor tissues. Typically, MRT uses arrays of narrow (˜25-100 micron-wide) microplanar beams separated by wider (100-400 microns centre-to-centre, c-t-c) microplanar spaces. We note that thicker microbeams of 0.1-0.68 mm used by investigators at the NSLS are still called microbeams, although some invesigators in the community prefer to call them minibeams. This report, however, limits it discussion to 25-100 μm microbeams. Peak entrance doses of several hundreds of Gy are surprisingly well tolerated by normal tissues. High resolution dosimetry has been developed over the last two decades, but typical dose ranges are adapted to dose delivery in conventional Radiation Therapy (RT). Spatial resolution in the sub-millimetric range has been achieved, which is currently required for quality assurance measurements in Gamma-knife RT. Most typical commercially available detectors are not suitable for MRT applications at a dose rate of 16000 Gy/s, micron

  18. 4MOST: the high-resolution spectrograph

    Science.gov (United States)

    Seifert, W.; Xu, W.; Buschkamp, P.; Feiz, C.; Saviauk, A.; Barden, S.; Quirrenbach, A.; Mandel, H.

    2016-08-01

    4MOST (4-meter Multi-Object Spectroscopic Telescope) is a wide-field, fiber-feed, high-multiplex spectroscopic survey facility to be installed on the 4-meter ESO telescope VISTA in Chile. It consists of two identical low resolution spectrographs and one high resolution spectrograph. The instrument is presently in the preliminary design phase and expected to get operational end of 2022. The high resolution spectrograph will afford simultaneous observations of up to 812 targets - over a hexagonal field of view of 4.1 sq.degrees on sky - with a spectral resolution R>18,000 covering a wavelength range from 393 to 679nm in three channels. In this paper we present the optical and mechanical design of the high resolution spectrograph (HRS) as prepared for the review at ESO, Garching. The expected performance including the highly multiplexed fiber slit concept is simulated and its impact on the optical performance given. We show the thermal and finite element analyses and the resulting stability of the spectrograph under operational conditions.

  19. High-Resolution PET Detector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Karp, Joel

    2014-03-26

    The objective of this project was to develop an understanding of the limits of performance for a high resolution PET detector using an approach based on continuous scintillation crystals rather than pixelated crystals. The overall goal was to design a high-resolution detector, which requires both high spatial resolution and high sensitivity for 511 keV gammas. Continuous scintillation detectors (Anger cameras) have been used extensively for both single-photon and PET scanners, however, these instruments were based on NaI(Tl) scintillators using relatively large, individual photo-multipliers. In this project we investigated the potential of this type of detector technology to achieve higher spatial resolution through the use of improved scintillator materials and photo-sensors, and modification of the detector surface to optimize the light response function.We achieved an average spatial resolution of 3-mm for a 25-mm thick, LYSO continuous detector using a maximum likelihood position algorithm and shallow slots cut into the entrance surface.

  20. Compact and high-resolution optical orbital angular momentum sorter

    Directory of Open Access Journals (Sweden)

    Chenhao Wan

    2017-03-01

    Full Text Available A compact and high-resolution optical orbital angular momentum (OAM sorter is proposed and demonstrated. The sorter comprises a quadratic fan-out mapper and a dual-phase corrector positioned in the pupil plane and the Fourier plane, respectively. The optical system is greatly simplified compared to previous demonstrations of OAM sorting, and the performance in resolution and efficiency is maintained. A folded configuration is set up using a single reflective spatial light modulator (SLM to demonstrate the validity of the scheme. The two phase elements are implemented on the left and right halves of the SLM and connected by a right-angle prism. Experimental results demonstrate the high resolution of the compact OAM sorter, and the current limit in efficiency can be overcome by replacing with transmissive SLMs and removing the beam splitters. This novel scheme paves the way for the miniaturization and integration of high-resolution OAM sorters.

  1. DUACS: Toward High Resolution Sea Level Products

    Science.gov (United States)

    Faugere, Y.; Gerald, D.; Ubelmann, C.; Claire, D.; Pujol, M. I.; Antoine, D.; Desjonqueres, J. D.; Picot, N.

    2016-12-01

    The DUACS system produces, as part of the CNES/SALP project, and the Copernicus Marine Environment and Monitoring Service, high quality multimission altimetry Sea Level products for oceanographic applications, climate forecasting centers, geophysic and biology communities... These products consist in directly usable and easy to manipulate Level 3 (along-track cross-calibrated SLA) and Level 4 products (multiple sensors merged as maps or time series) and are available in global and regional version (Mediterranean Sea, Arctic, European Shelves …).The quality of the products is today limited by the altimeter technology "Low Resolution Mode" (LRM), and the lack of available observations. The launch of 2 new satellites in 2016, Jason-3 and Sentinel-3A, opens new perspectives. Using the global Synthetic Aperture Radar mode (SARM) coverage of S3A and optimizing the LRM altimeter processing (retracking, editing, ...) will allow us to fully exploit the fine-scale content of the altimetric missions. Thanks to this increase of real time altimetry observations we will also be able to improve Level-4 products by combining these new Level-3 products and new mapping methodology, such as dynamic interpolation. Finally these improvements will benefit to downstream products : geostrophic currents, Lagrangian products, eddy atlas… Overcoming all these challenges will provide major upgrades of Sea Level products to better fulfill user needs.

  2. A High Resolution Scale-of-four

    Science.gov (United States)

    Fitch, V.

    1949-08-25

    A high resolution scale-of-four has been developed to be used in conjunction with the nuclear particle detection devices in applications where the counting rate is unusually high. Specifically, it is intended to precede the commercially available medium resolution scaling circuits and so decrease the resolving time of the counting system. The circuit will function reliably on continuously recurring pulses separated by less than 0.1 microseconds. It will resolve two pulses (occurring at a moderate repetition rate) which are spaced at 0.04 microseconds. A five-volt input signal is sufficient to actuate the device.

  3. Single shot high resolution digital holography.

    Science.gov (United States)

    Khare, Kedar; Ali, P T Samsheer; Joseph, Joby

    2013-02-11

    We demonstrate a novel computational method for high resolution image recovery from a single digital hologram frame. The complex object field is obtained from the recorded hologram by solving a constrained optimization problem. This approach which is unlike the physical hologram replay process is shown to provide high quality image recovery even when the dc and the cross terms in the hologram overlap in the Fourier domain. Experimental results are shown for a Fresnel zone hologram of a resolution chart, intentionally recorded with a small off-axis reference beam angle. Excellent image recovery is observed without the presence of dc or twin image terms and with minimal speckle noise.

  4. High-resolution electrohydrodynamic jet printing

    Science.gov (United States)

    Park, Jang-Ung; Hardy, Matt; Kang, Seong Jun; Barton, Kira; Adair, Kurt; Mukhopadhyay, Deep Kishore; Lee, Chang Young; Strano, Michael S.; Alleyne, Andrew G.; Georgiadis, John G.; Ferreira, Placid M.; Rogers, John A.

    2007-10-01

    Efforts to adapt and extend graphic arts printing techniques for demanding device applications in electronics, biotechnology and microelectromechanical systems have grown rapidly in recent years. Here, we describe the use of electrohydrodynamically induced fluid flows through fine microcapillary nozzles for jet printing of patterns and functional devices with submicrometre resolution. Key aspects of the physics of this approach, which has some features in common with related but comparatively low-resolution techniques for graphic arts, are revealed through direct high-speed imaging of the droplet formation processes. Printing of complex patterns of inks, ranging from insulating and conducting polymers, to solution suspensions of silicon nanoparticles and rods, to single-walled carbon nanotubes, using integrated computer-controlled printer systems illustrates some of the capabilities. High-resolution printed metal interconnects, electrodes and probing pads for representative circuit patterns and functional transistors with critical dimensions as small as 1μm demonstrate potential applications in printed electronics.

  5. Smartphone microendoscopy for high resolution fluorescence imaging

    CERN Document Server

    Hong, Xiangqian; Mugler, Dale H; Yu, Bing

    2016-01-01

    High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the gastrointestinal tracts, but they are too expensive for use in resource-poor settings. On the other hand, smartphones with high resolution cameras and Internet access have become more affordable, enabling them to diffuse into most rural areas and developing countries in the past decade. In this letter we describe a smartphone microendoscope that can take fluorescence images with a spatial resolution of 3.1 {\\mu}m. Images collected from ex vivo, in vitro and in vivo samples using the device are also presented. The compact and cost-effective smartphone microendoscope may be envisaged as a powerful tool for detecting pre-cancerous lesions of internal organs in low and middle income countries.

  6. High-resolution noise radar using slow ADC

    Science.gov (United States)

    Lukin, Konstantin; Vyplavin, Pavlo; Zemlyanyi, Oleg; Lukin, Sergiy; Palamarchuk, Volodymyr

    2011-06-01

    Conventional digital signal processing scheme in noise radars has some limitations related to combination of high resolution and high dynamic range. Those limitations are caused by a tradeoff in performance of currently available ADCs: the faster is ADC the smaller is its depth (number of bits) available. Depth of the ADC determines relation between the smallest and highest observable signals and thus limits its dynamic range. In noise radar with conventional processing the sounding and reference signals are to be digitized at intermediate frequency band and to be processed digitally. The power spectrum bandwidth of noise signal which can be digitized with ADC depends on its sampling rate. The bandwidth of radar signal defines range resolution of any radar: the wider the spectrum the better the resolution. Actually this is the main bottleneck of high resolution Noise Radars: conventional processing doesn't enable to get both high range resolution and high dynamic range. In the paper we present a way to go around this drawback by changing signal processing ideology in noise radar. We present results of our consideration and design of high resolution Noise Radar which uses slow ADCs. The design is based upon generation of both probing and reference signals digitally and realization of their cross-correlation in an analog correlator. The output of the correlator is a narrowband signal that requires rather slow ADC to be sampled which nowadays may give up to 130 dB dynamic range.

  7. Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing

    CERN Document Server

    Arridge, Simon; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-01-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue. A particular example is the planar Fabry-Perot (FP) scanner, which yields high-resolution images but takes several minutes to sequentially map the photoacoustic field on the sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: First, we describe and model two general spatial sub-sampling schemes. Then...

  8. A Very High Spatial Resolution Detector for Small Animal PET

    Energy Technology Data Exchange (ETDEWEB)

    Kanai Shah, M.S.

    2007-03-06

    Positron Emission Tomography (PET) is an in vivo analog of autoradiography and has the potential to become a powerful new tool in imaging biological processes in small laboratory animals. PET imaging of small animals can provide unique information that can help in advancement of human disease models as well as drug development. Clinical PET scanners used for human imaging are bulky, expensive and do not have adequate spatial resolution for small animal studies. Hence, dedicated, low cost instruments are required for conducting small animal studies with higher spatial resolution than what is currently achieved with clinical as well as dedicated small animal PET scanners. The goal of the proposed project is to investigate a new all solid-state detector design for small animal PET imaging. Exceptionally high spatial resolution, good timing resolution, and excellent energy resolution are expected from the proposed detector design. The Phase I project was aimed at demonstrating the feasibility of producing high performance solid-state detectors that provide high sensitivity, spatial resolution, and timing characteristics. Energy resolution characteristics of the new detector were also investigated. The goal of the Phase II project is to advance the promising solid-state detector technology for small animal PET and determine its full potential. Detectors modules will be built and characterized and finally, a bench-top small animal PET system will be assembled and evaluated.

  9. The future of high resolution electron microscopy

    Institute of Scientific and Technical Information of China (English)

    D Van Dyck

    2000-01-01

    The state of the art and the future in quantitative high resolution electron microscopy are discussed in the framework of parameter estimation. Reconstruction methods are then to be considered as direct methods to yield a starting structure for further refinement. With the increasing flexibility of the instruments, computer aided experimental strategy will become important.

  10. High resolution spectroscopy of planet bearing stars

    Directory of Open Access Journals (Sweden)

    M. C. Gálvez

    2007-01-01

    Full Text Available We present here the first steps of an extended spectroscopic survey in order to characterize the stellar hosts of extra-solar planets. We have selected several known stars with plan- ets and using high resolution spectroscopy, we have studied their properties.

  11. High-resolution seismic profiling on water

    OpenAIRE

    McGee, T.M.

    2000-01-01

    Herein is presented an overview of high-resolution seismic profiling on water. Included are basic concepts and terminology as well as discussions of types of sources and receivers, field practice, data recording and data processing. Emphasis is on digital single-channel profiling for engineering and environmental purposes.

  12. Compact high-resolution spectral phase shaper

    NARCIS (Netherlands)

    Postma, S.; Walle, van der P.; Offerhaus, H.L.; Hulst, van N.F.

    2005-01-01

    The design and operation of a high-resolution spectral phase shaper with a footprint of only 7×10 cm2 is presented. The liquid-crystal modulator has 4096 elements. More than 600 independent degrees of freedom can be positioned with a relative accuracy of 1 pixel. The spectral shaping of pulses fro

  13. A High-Resolution Stopwatch for Cents

    Science.gov (United States)

    Gingl, Z.; Kopasz, K.

    2011-01-01

    A very low-cost, easy-to-make stopwatch is presented to support various experiments in mechanics. The high-resolution stopwatch is based on two photodetectors connected directly to the microphone input of a sound card. Dedicated free open-source software has been developed and made available to download. The efficiency is demonstrated by a free…

  14. Compressive sensing for high resolution radar imaging

    NARCIS (Netherlands)

    Anitori, L.; Otten, M.P.G.; Hoogeboom, P.

    2010-01-01

    In this paper we present some preliminary results on the application of Compressive Sensing (CS) to high resolution radar imaging. CS is a recently developed theory which allows reconstruction of sparse signals with a number of measurements much lower than what is required by the Shannon sampling th

  15. The High Time Resolution Radio Sky

    Science.gov (United States)

    Thornton, D.

    2013-11-01

    Pulsars are laboratories for extreme physics unachievable on Earth. As individual sources and possible orbital companions can be used to study magnetospheric, emission, and superfluid physics, general relativistic effects, and stellar and binary evolution. As populations they exhibit a wide range of sub-types, with parameters varying by many orders of magnitude signifying fundamental differences in their evolutionary history and potential uses. There are currently around 2200 known pulsars in the Milky Way, the Magellanic clouds, and globular clusters, most of which have been discovered with radio survey observations. These observations, as well as being suitable for detecting the repeating signals from pulsars, are well suited for identifying other transient astronomical radio bursts that last just a few milliseconds that either singular in nature, or rarely repeating. Prior to the work of this thesis non-repeating radio transients at extragalactic distances had possibly been discovered, however with just one example status a real astronomical sources was in doubt. Finding more of these sources was a vital to proving they were real and to open up the universe for millisecond-duration radio astronomy. The High Time Resolution Universe survey uses the multibeam receiver on the 64-m Parkes radio telescope to search the whole visible sky for pulsars and transients. The temporal and spectral resolution of the receiver and the digital back-end enable the detection of relatively faint, and distant radio sources. From the Parkes telescope a large portion of the Galactic plane can be seen, a rich hunting ground for radio pulsars of all types, while previously poorly surveyed regions away from the Galactic plane are also covered. I have made a number of pulsar discoveries in the survey, including some rare systems. These include PSR J1226-6208, a possible double neutron star system in a remarkably circular orbit, PSR J1431-471 which is being eclipsed by its companion with

  16. Constructing a WISE High Resolution Galaxy Atlas

    Science.gov (United States)

    Jarrett, T. H.; Masci, F.; Tsai, C. W.; Petty, S.; Cluver, M.; Assef, Roberto J.; Benford, D.; Blain, A.; Bridge, C.; Donoso, E.; Eisenhardt, P.; Fowler, J.; Koribalski, B.; Lake, S.; Neill, James D.; Seibert, M.; Stanford, S.; Wright, E.

    2012-01-01

    After eight months of continuous observations, the Wide-field Infrared Survey Explorer (WISE) mapped the entire sky at 3.4 micron, 4.6 micron, 12 micron, and 22 micron. We have begun a dedicated WISE High Resolution Galaxy Atlas project to fully characterize large, nearby galaxies and produce a legacy image atlas and source catalog. Here we summarize the deconvolution techniques used to significantly improve the spatial resolution of WISE imaging, specifically designed to study the internal anatomy of nearby galaxies. As a case study, we present results for the galaxy NGC 1566, comparing the WISE enhanced-resolution image processing to that of Spitzer, Galaxy Evolution Explorer, and ground-based imaging. This is the first paper in a two-part series; results for a larger sample of nearby galaxies are presented in the second paper.

  17. High-resolution traction force microscopy.

    Science.gov (United States)

    Plotnikov, Sergey V; Sabass, Benedikt; Schwarz, Ulrich S; Waterman, Clare M

    2014-01-01

    Cellular forces generated by the actomyosin cytoskeleton and transmitted to the extracellular matrix (ECM) through discrete, integrin-based protein assemblies, that is, focal adhesions, are critical to developmental morphogenesis and tissue homeostasis, as well as disease progression in cancer. However, quantitative mapping of these forces has been difficult since there has been no experimental technique to visualize nanonewton forces at submicrometer spatial resolution. Here, we provide detailed protocols for measuring cellular forces exerted on two-dimensional elastic substrates with a high-resolution traction force microscopy (TFM) method. We describe fabrication of polyacrylamide substrates labeled with multiple colors of fiducial markers, functionalization of the substrates with ECM proteins, setting up the experiment, and imaging procedures. In addition, we provide the theoretical background of traction reconstruction and experimental considerations important to design a high-resolution TFM experiment. We describe the implementation of a new algorithm for processing of images of fiducial markers that are taken below the surface of the substrate, which significantly improves data quality. We demonstrate the application of the algorithm and explain how to choose a regularization parameter for suppression of the measurement error. A brief discussion of different ways to visualize and analyze the results serves to illustrate possible uses of high-resolution TFM in biomedical research. © 2014 Elsevier Inc. All rights reserved.

  18. Development of a high resolution and high dispersion Thomson parabola.

    Science.gov (United States)

    Jung, D; Hörlein, R; Kiefer, D; Letzring, S; Gautier, D C; Schramm, U; Hübsch, C; Öhm, R; Albright, B J; Fernandez, J C; Habs, D; Hegelich, B M

    2011-01-01

    Here, we report on the development of a novel high resolution and high dispersion Thomson parabola for simultaneously resolving protons and low-Z ions of more than 100 MeV/nucleon necessary to explore novel laser ion acceleration schemes. High electric and magnetic fields enable energy resolutions of ΔE∕E parabola for ion energies of more than 30 MeV/nucleon.

  19. High-current, high-frequency capacitors

    Science.gov (United States)

    Renz, D. D.

    1983-06-01

    The NASA Lewis high-current, high-frequency capacitor development program was conducted under a contract with Maxwell Laboratories, Inc., San Diego, California. The program was started to develop power components for space power systems. One of the components lacking was a high-power, high-frequency capacitor. Some of the technology developed in this program may be directly usable in an all-electric airplane. The materials used in the capacitor included the following: the film is polypropylene, the impregnant is monoisopropyl biphenyl, the conductive epoxy is Emerson and Cuming Stycast 2850 KT, the foil is aluminum, the case is stainless steel (304), and the electrode is a modified copper-ceramic.

  20. Development and evaluation of a high-resolution reanalysis of the East Australian Current region using the Regional Ocean Modelling System (ROMS 3.4) and Incremental Strong-Constraint 4-Dimensional Variational (IS4D-Var) data assimilation

    Science.gov (United States)

    Kerry, Colette; Powell, Brian; Roughan, Moninya; Oke, Peter

    2016-10-01

    As with other Western Boundary Currents globally, the East Australian Current (EAC) is highly variable making it a challenge to model and predict. For the EAC region, we combine a high-resolution state-of-the-art numerical ocean model with a variety of traditional and newly available observations using an advanced variational data assimilation scheme. The numerical model is configured using the Regional Ocean Modelling System (ROMS 3.4) and takes boundary forcing from the BlueLink ReANalysis (BRAN3). For the data assimilation, we use an Incremental Strong-Constraint 4-Dimensional Variational (IS4D-Var) scheme, which uses the model dynamics to perturb the initial conditions, atmospheric forcing, and boundary conditions, such that the modelled ocean state better fits and is in balance with the observations. This paper describes the data assimilative model configuration that achieves a significant reduction of the difference between the modelled solution and the observations to give a dynamically consistent "best estimate" of the ocean state over a 2-year period. The reanalysis is shown to represent both assimilated and non-assimilated observations well. It achieves mean spatially averaged root mean squared (rms) residuals with the observations of 7.6 cm for sea surface height (SSH) and 0.4 °C for sea surface temperature (SST) over the assimilation period. The time-mean rms residual for subsurface temperature measured by Argo floats is a maximum of 0.9 °C between water depths of 100 and 300 m and smaller throughout the rest of the water column. Velocities at several offshore and continental shelf moorings are well represented in the reanalysis with complex correlations between 0.8 and 1 for all observations in the upper 500 m. Surface radial velocities from a high-frequency radar array are assimilated and the reanalysis provides surface velocity estimates with complex correlations with observed velocities of 0.8-1 across the radar footprint. A comparison with

  1. High resolution positron tomography using PCR-I

    Energy Technology Data Exchange (ETDEWEB)

    Brownell, G.L.; Burnham, C.A.; Sandrew, B.; Elmaleh, D.R.; Livni, E.; Kizuka, H.

    1984-01-01

    PCR-I is a high resolution positron tomograph developed by the Physics Research Laboratory of the Massachusetts General Hospital to explore resolution limits of positron tomographs. PCR-I currently obtains images with 4.8 mm FWHM resolution at the center. Plane thickness may be varied between 5 and 10 mm. The instrument uses analog coding to obtain high resolution images without mechanical motion. This permits rapid dynamic imaging and gated cardiac imaging as well as conventional high resolution imaging. A series of studies has been carried out to demonstrate the ability of PCR-I to image structures in small animals. F-18 in the rat skeleton is clearly defined and various structures such as the spinal processes can be clearly resolved. A sequence of images at different spacing provides a three-dimensional reconstruction of the rat skeleton. Blood volume and palmitic acid have been imaged in the dog heart. Again, the sequence of images provides a clear delineation of the three dimensional nature of the blood pools and of the surrounding musculature. Blood flow, blood volume and glucose metabolism have been studied in the monkey brain. Structures within the brain of the Resus monkey can be clearly resolved. Increased activity resulting from induced seizures in the squirrel monkey have been observed and delineated. All of these studies indicate areas of future animal and clinical research using the high resolution tomograph, PCR-I.

  2. High-resolution low-dose scanning transmission electron microscopy.

    Science.gov (United States)

    Buban, James P; Ramasse, Quentin; Gipson, Bryant; Browning, Nigel D; Stahlberg, Henning

    2010-01-01

    During the past two decades instrumentation in scanning transmission electron microscopy (STEM) has pushed toward higher intensity electron probes to increase the signal-to-noise ratio of recorded images. While this is suitable for robust specimens, biological specimens require a much reduced electron dose for high-resolution imaging. We describe here protocols for low-dose STEM image recording with a conventional field-emission gun STEM, while maintaining the high-resolution capability of the instrument. Our findings show that a combination of reduced pixel dwell time and reduced gun current can achieve radiation doses comparable to low-dose TEM.

  3. High resolution 3D nonlinear integrated inversion

    Institute of Scientific and Technical Information of China (English)

    Li Yong; Wang Xuben; Li Zhirong; Li Qiong; Li Zhengwen

    2009-01-01

    The high resolution 3D nonlinear integrated inversion method is based on nonlinear theory. Under layer control, the log data from several wells (or all wells) in the study area and seismic trace data adjacent to the wells are input to a network with multiple inputs and outputs and are integratedly trained to obtain an adaptive weight function of the entire study area. Integrated nonlinear mapping relationships are built and updated by the lateral and vertical geologic variations of the reservoirs. Therefore, the inversion process and its inversion results can be constrained and controlled and a stable seismic inversion section with high resolution with velocity inversion, impedance inversion, and density inversion sections, can be gained. Good geologic effects have been obtained in model computation tests and real data processing, which verified that this method has high precision, good practicality, and can be used for quantitative reservoir analysis.

  4. Progress toward high resolution EUV spectroscopy

    Science.gov (United States)

    Korendyke, C.; Doschek, G. A.; Warren, H.; Young, P. R.; Chua, D.; Hassler, D. M.; Landi, E.; Davila, J. M.; Klimchuck, J.; Tun, S.; DeForest, C.; Mariska, J. T.; Solar C Spectroscopy Working Group; LEMUR; EUVST Development Team

    2013-07-01

    HIgh resolution EUV spectroscopy is a critical instrumental technique to understand fundamental physical processes in the high temperature solar atmosphere. Spectroscopic observations are used to measure differential emission measure, line of sight and turbulent flows, plasma densities and emission measures. Spatially resolved, spectra of these emission lines with adequate cadence will provide the necessary clues linking small scale structures with large scale, energetic solar phenomena. The necessary observations to determine underlying physical processes and to provide comprehensive temperature coverage of the solar atmosphere above the chromosphere will be obtained by the proposed EUVST instrument for Solar C. This instrument and its design will be discussed in this paper. Progress on the VEry high Resolution Imaging Spectrograph (VERIS) sounding rocket instrument presently under development at the Naval Research Laboratory will also be discussed.

  5. Superconducting High Resolution Fast-Neutron Spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Hau, Ionel Dragos [Univ. of California, Berkeley, CA (United States)

    2006-01-01

    Superconducting high resolution fast-neutron calorimetric spectrometers based on 6LiF and TiB{sub 2} absorbers have been developed. These novel cryogenic spectrometers measure the temperature rise produced in exothermal (n, α) reactions with fast neutrons in 6Li and 10B-loaded materials with heat capacity C operating at temperatures T close to 0.1 K. Temperature variations on the order of 0.5 mK are measured with a Mo/Cu thin film multilayer operated in the transition region between its superconducting and its normal state. The advantage of calorimetry for high resolution spectroscopy is due to the small phonon excitation energies kBT on the order of μeV that serve as signal carriers, resulting in an energy resolution ΔE ~ (kBT2C)1/2, which can be well below 10 keV. An energy resolution of 5.5 keV has been obtained with a Mo/Cu superconducting sensor and a TiB2 absorber using thermal neutrons from a 252Cf neutron source. This resolution is sufficient to observe the effect of recoil nuclei broadening in neutron spectra, which has been related to the lifetime of the first excited state in 7Li. Fast-neutron spectra obtained with a 6Li-enriched LiF absorber show an energy resolution of 16 keV FWHM, and a response in agreement with the 6Li(n, α)3H reaction cross section and Monte Carlo simulations for energies up to several MeV. The energy resolution of order of a few keV makes this novel instrument applicable to fast-neutron transmission spectroscopy based on the unique elemental signature provided by the neutron absorption and scattering resonances. The optimization of the energy resolution based on analytical and numerical models of the detector response is discussed in the context of these applications.

  6. On the numerical resolution of the bottom layer in simulations of oceanic gravity currents

    Directory of Open Access Journals (Sweden)

    N. Laanaia

    2010-06-01

    Full Text Available The role of an increased numerical vertical resolution, leading to an explicit resolution of the bottom Ekman layer dynamics, is investigated. Using the hydrostatic ocean model NEMO-OPA9, we demonstrate that the dynamics of an idealised gravity current (on an inclined plane, is well captured when a few (around five sigma-coordinate levels are added near the ocean floor. Such resolution allows to considerably improve the representation of the descent and transport of the gravity current and the Ekman dynamics near the ocean floor, including the important effect of Ekman veering, which is usually neglected in today's simulations of the ocean dynamics.

    Results from high resolution simulations (with σ and z-coordinates are compared to simulations with a vertical resolution commonly employed in today's ocean models. The latter show a downslope transport that is reduced by almost an order of magnitude and the decrease in the along slope transport is reduced six-fold. We strongly advocate for an increase of the numerical resolution at the ocean floor, similar to the way it is done at the ocean surface and at the lower boundary in atmospheric models.

  7. On the numerical resolution of the bottom layer in simulations of oceanic gravity currents

    Directory of Open Access Journals (Sweden)

    N. Laanaia

    2010-03-01

    Full Text Available The role of an increased numerical vertical resolution, leading to an explicit resolution of the bottom Ekman layer dynamics, is investigated. Using the hydrostatic ocean model NEMO-OPA9, we demonstrate that the dynamics of an idealised gravity current (on an inclined plane, is well captured when a few (around five sigma-coordinate levels are added near the ocean floor. Such resolution allows to considerably improve the representation of the descent and transport of the gravity current and the Ekman dynamics near the ocean floor, including the important effect of Ekman veering, which is usually neglected in today's simulations of the ocean dynamics.

    Results from high resolution simulations (with σ and z-coordinates are compared to simulations with a vertical resolution commonly employed in today's ocean models. The latter show a downslope transport that is reduced by almost an order of magnitude and the decrease in the along slope transport is reduced six-fold. We strongly advocate for an increase of the numerical resolution at the ocean floor, similar to the way it is done at the ocean surface and at the lower boundary in atmospheric models.

  8. High-Resolution US of Rheumatologic Diseases.

    Science.gov (United States)

    Taljanovic, Mihra S; Melville, David M; Gimber, Lana H; Scalcione, Luke R; Miller, Margaret D; Kwoh, C Kent; Klauser, Andrea S

    2015-01-01

    For the past 15 years, high-resolution ultrasonography (US) is being routinely and increasingly used for initial evaluation and treatment follow-up of rheumatologic diseases. This imaging technique is performed by using high-frequency linear transducers and has proved to be a powerful diagnostic tool in evaluation of articular erosions, simple and complex joint and bursal effusions, tendon sheath effusions, and synovitis, with results comparable to those of magnetic resonance imaging, excluding detection of bone marrow edema. Crystal deposition diseases including gouty arthropathy and calcium pyrophosphate deposition disease (CPPD) have characteristic appearances at US, enabling differentiation between these two diseases and from inflammatory arthropathies. Enthesopathy, which frequently accompanies psoriatic and reactive arthritis, also has a characteristic appearance at high-resolution US, distinguishing these two entities from other inflammatory and metabolic arthropathies. The presence of Doppler signal in examined joints, bursae, and tendon sheaths indicates active synovitis. Microbubble echo contrast agents augment detection of tissue vascularity and may act in the future as a drug delivery vehicle. Frequently, joint, tendon sheath, and bursal fluid aspirations and therapeutic injections are performed under US guidance. The authors describe the high-resolution US technique including gray-scale, color or power Doppler, and contrast agent-enhanced US that is used in evaluation of rheumatologic diseases of the wrist and hand and the ankle and foot in their routine clinical practice. This article demonstrates imaging findings of normal joints, rheumatoid arthritis, gouty arthritis, CPPD, psoriatic and reactive arthritis, and osteoarthritis.

  9. Bendable X-ray Optics for High Resolution Imaging

    Science.gov (United States)

    Gubarev, M.; Ramsey, B.; Kilaru, K.; Atkins, C.; Broadway, D.

    2014-01-01

    Current state-of the-art for x-ray optics fabrication calls for either the polishing of massive substrates into high-angular-resolution mirrors or the replication of thin, lower-resolution, mirrors from perfectly figured mandrels. Future X-ray Missions will require a change in this optics fabrication paradigm in order to achieve sub-arcsecond resolution in light-weight optics. One possible approach to this is to start with perfectly flat, light-weight surface, bend it into a perfect cone, form the desired mirror figure by material deposition, and insert the resulting mirror into a telescope structure. Such an approach is currently being investigated at MSFC, and a status report will be presented detailing the results of finite element analyses, bending tests and differential deposition experiments.

  10. High-resolution flurescence spectroscopy in immunoanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Grubor, Nenad M.

    2005-05-01

    The work presented in this dissertation combines highly sensitive and selective fluorescence line-narrowing spectroscopy (FLNS) detection with various modes of immunoanalytical techniques. It has been shown that FLNS is capable of directly probing molecules immunocomplexed with antibodies, eliminating analytical ambiguities that may arise from interferences that accompany traditional immunochemical techniques. Moreover, the utilization of highly cross-reactive antibodies for highly specific analyte determination has been demonstrated. Finally, they demonstrate the first example of the spectral resolution of diastereomeric analytes based on their interaction with a cross-reactive antibody.

  11. High-resolution flurescence spectroscopy in immunoanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Grubor, Nenad M. [Iowa State Univ., Ames, IA (United States)

    2005-01-01

    The work presented in this dissertation combines highly sensitive and selective fluorescence line-narrowing spectroscopy (FLNS) detection with various modes of immunoanalytical techniques. It has been shown that FLNS is capable of directly probing molecules immunocomplexed with antibodies, eliminating analytical ambiguities that may arise from interferences that accompany traditional immunochemical techniques. Moreover, the utilization of highly cross-reactive antibodies for highly specific analyte determination has been demonstrated. Finally, they demonstrate the first example of the spectral resolution of diastereomeric analytes based on their interaction with a cross-reactive antibody.

  12. High-resolution TOF with RPCs

    Energy Technology Data Exchange (ETDEWEB)

    Fonte, P. E-mail: fonte@lipc.fis.uc.pt; Peskov, V

    2002-01-21

    In this work, we describe some recent results concerning the application of Resistive Plate Chambers operated in avalanche mode at atmospheric pressure for high-resolution time-of-flight measurements. A combination of multiple, mechanically accurate, thin gas gaps and state-of-the-art electronics yielded an overall (detector plus electronics) timing accuracy better than 50 ps {sigma} with a detection efficiency up to 99% for MIPs. Single gap chambers were also tested in order to clarify experimentally several aspects of the mode of operation of these detectors. These results open perspectives of affordable and reliable high granularity large area TOF detectors, with an efficiency and time resolution comparable to the existing scintillator-based TOF technology but with a significantly, up to an order of magnitude, lower price per channel.

  13. Structural High-resolution Satellite Image Indexing

    OpenAIRE

    Xia, Gui-Song; YANG, WEN; Delon, Julie; Gousseau, Yann; Sun, Hong; Maître, Henri

    2010-01-01

    International audience; Satellite images with high spatial resolution raise many challenging issues in image understanding and pattern recognition. First, they allow measurement of small objects maybe up to 0.5 m, and both texture and geometrical structures emerge simultaneously. Second, objects in the same type of scenes might appear at different scales and orientations. Consequently, image indexing methods should combine the structure and texture information of images and comply with some i...

  14. Stellar Tools for High Resolution Population Synthesis

    Science.gov (United States)

    Chávez, M.; Bertone, E.; Rodríguez-Merino, L.; Buzzoni, A.

    2005-12-01

    We present preliminary results of the application of a new stellar library of high-resolution synthetic spectra (based upon ATLAS9 and SYNTHE codes developed by R. L. Kurucz) in the calculation of the ultraviolet-optical spectral energy distribution of simple stellar populations (SSPs). For this purpose, the library has been coupled with Buzzoni's population synthesis code. Part of this paper is also devoted to illustrate quantitatively the extent to which synthetic stellar libraries represent real stars.

  15. Petrous apex mucocele: high resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Memis, A. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Memis, A. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Alper, H. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Calli, C. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Ozer, H. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Ozdamar, N. [Dept. of Neurosurgery, Hospital of Ege Univ., Bornova, Izmir (Turkey)

    1994-11-01

    Mucocele of the petrous apex is very rare, only three cases having been reported. Since this area is inaccessible to direct examination, imaging, preferably high resolution computed tomography (HR CT) is essential. We report a case showing an eroding, non enhancing mass with sharp, lobulated contours, within the petrous apex. The presence of a large air cell on the opposite side suggested a mucocele. (orig.)

  16. High resolution NMR theory and chemical applications

    CERN Document Server

    Becker, Edwin D

    1969-01-01

    High Resolution NMR: Theory and Chemical Applications focuses on the applications of nuclear magnetic resonance (NMR), as well as chemical shifts, lattices, and couplings. The book first offers information on the theory of NMR, including nuclear spin and magnetic moment, spin lattice relaxation, line widths, saturation, quantum mechanical description of NMR, and ringing. The text then ponders on instrumentation and techniques and chemical shifts. Discussions focus on the origin of chemical shifts, reference compounds, empirical correlations of chemical shifts, modulation and phase detection,

  17. High Sensitivity, High Frequency and High Time Resolution Decimetric Spectroscope

    Science.gov (United States)

    Sawant, H. S.; Rosa, R. R.

    1990-11-01

    RESUMEN. Se ha desarrollado el primer espectroscopio decimetrico latino americano operando en una banda de 100 MHz con alta resoluci6n de fre- cuencia (100 KHz) y tiempo (10 ms), alrededor de cualquier centro de frecuencia en el intervalo de 2000-200 MHz. El prop6sito de esta nota es describir investigaciones solares y no solares que se planean, progra ma de investigaci6n y la situaci6n actual de desarrollo de este espectroscopio. ABSTRACT. First Latin American Decimetric Spectroscope operating over a band of 100 MHz with high resolution in frequency (100 KHz) and time (10 ms), around any center frequency in the range of 2000-200 MHz is being developed. The purpose of this note is to describe planned solar, and non-solar, research programmes and present status of development of this spectroscope. Keq wo : INSTRUMENTS - SPECTROSCOPY

  18. High Resolution Measurement of the Glycolytic Rate

    Science.gov (United States)

    Bittner, Carla X.; Loaiza, Anitsi; Ruminot, Iván; Larenas, Valeria; Sotelo-Hitschfeld, Tamara; Gutiérrez, Robin; Córdova, Alex; Valdebenito, Rocío; Frommer, Wolf B.; Barros, L. Felipe

    2010-01-01

    The glycolytic rate is sensitive to physiological activity, hormones, stress, aging, and malignant transformation. Standard techniques to measure the glycolytic rate are based on radioactive isotopes, are not able to resolve single cells and have poor temporal resolution, limitations that hamper the study of energy metabolism in the brain and other organs. A new method is described in this article, which makes use of a recently developed FRET glucose nanosensor to measure the rate of glycolysis in single cells with high temporal resolution. Used in cultured astrocytes, the method showed for the first time that glycolysis can be activated within seconds by a combination of glutamate and K+, supporting a role for astrocytes in neurometabolic and neurovascular coupling in the brain. It was also possible to make a direct comparison of metabolism in neurons and astrocytes lying in close proximity, paving the way to a high-resolution characterization of brain energy metabolism. Single-cell glycolytic rates were also measured in fibroblasts, adipocytes, myoblasts, and tumor cells, showing higher rates for undifferentiated cells and significant metabolic heterogeneity within cell types. This method should facilitate the investigation of tissue metabolism at the single-cell level and is readily adaptable for high-throughput analysis. PMID:20890447

  19. High resolution measurement of the glycolytic rate

    Directory of Open Access Journals (Sweden)

    Carla X Bittner

    2010-09-01

    Full Text Available The glycolytic rate is sensitive to physiological activity, hormones, stress, aging and malignant transformation. Standard techniques to measure the glycolytic rate are based on radioactive isotopes, are not able to resolve single cells and have poor temporal resolution, limitations that hamper the study of energy metabolism in the brain and other organs. A new method is described in this article, which makes use of a recently-developed FRET glucose nanosensor to measure the rate of glycolysis in single cells with high temporal resolution. Used in cultured astrocytes, the method showed for the first time that glycolysis can be activated within seconds by a combination of glutamate and K+, supporting a role for astrocytes in neurometabolic and neurovascular coupling in the brain. It was also possible to make a direct comparison of metabolism in neurons and astrocytes lying in close proximity, paving the way to a high-resolution characterization of brain energy metabolism. Single-cell glycolytic rates were also measured in fibroblasts, adipocytes, myoblasts and tumor cells, showing higher rates for undifferentiated cells and significant metabolic heterogeneity within cell types. This method should facilitate the investigation of tissue metabolism at the single-cell level and is readily adaptable for high-throughput analysis.

  20. Extension of least squares spectral resolution algorithm to high-resolution lipidomics data

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Ying-Xu [Department of Chemistry, University of Bergen, PO Box 7803, N-5020 Bergen (Norway); Mjøs, Svein Are, E-mail: svein.mjos@kj.uib.no [Department of Chemistry, University of Bergen, PO Box 7803, N-5020 Bergen (Norway); David, Fabrice P.A. [Bioinformatics and Biostatistics Core Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL) and Swiss Institute of Bioinformatics (SIB), Lausanne (Switzerland); Schmid, Adrien W. [Proteomics Core Facility, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne (Switzerland)

    2016-03-31

    Lipidomics, which focuses on the global study of molecular lipids in biological systems, has been driven tremendously by technical advances in mass spectrometry (MS) instrumentation, particularly high-resolution MS. This requires powerful computational tools that handle the high-throughput lipidomics data analysis. To address this issue, a novel computational tool has been developed for the analysis of high-resolution MS data, including the data pretreatment, visualization, automated identification, deconvolution and quantification of lipid species. The algorithm features the customized generation of a lipid compound library and mass spectral library, which covers the major lipid classes such as glycerolipids, glycerophospholipids and sphingolipids. Next, the algorithm performs least squares resolution of spectra and chromatograms based on the theoretical isotope distribution of molecular ions, which enables automated identification and quantification of molecular lipid species. Currently, this methodology supports analysis of both high and low resolution MS as well as liquid chromatography-MS (LC-MS) lipidomics data. The flexibility of the methodology allows it to be expanded to support more lipid classes and more data interpretation functions, making it a promising tool in lipidomic data analysis. - Highlights: • A flexible strategy for analyzing MS and LC-MS data of lipid molecules is proposed. • Isotope distribution spectra of theoretically possible compounds were generated. • High resolution MS and LC-MS data were resolved by least squares spectral resolution. • The method proposed compounds that are likely to occur in the analyzed samples. • The proposed compounds matched results from manual interpretation of fragment spectra.

  1. SPIRAL2/DESIR high resolution mass separator

    Energy Technology Data Exchange (ETDEWEB)

    Kurtukian-Nieto, T., E-mail: kurtukia@cenbg.in2p3.fr [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Baartman, R. [TRIUMF, 4004 Wesbrook Mall, Vancouver B.C., V6T 2A3 (Canada); Blank, B.; Chiron, T. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Davids, C. [Physics Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Delalee, F. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Duval, M. [GANIL, CEA/DSM-CNRS/IN2P3, Bd Henri Becquerel, BP 55027, F-14076 Caen Cedex 5 (France); El Abbeir, S.; Fournier, A. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Lunney, D. [CSNSM-IN2P3-CNRS, Université de Paris Sud, F-91405 Orsay (France); Méot, F. [BNL, Upton, Long Island, New York (United States); Serani, L. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Stodel, M.-H.; Varenne, F. [GANIL, CEA/DSM-CNRS/IN2P3, Bd Henri Becquerel, BP 55027, F-14076 Caen Cedex 5 (France); and others

    2013-12-15

    DESIR is the low-energy part of the SPIRAL2 ISOL facility under construction at GANIL. DESIR includes a high-resolution mass separator (HRS) with a designed resolving power m/Δm of 31,000 for a 1 π-mm-mrad beam emittance, obtained using a high-intensity beam cooling device. The proposed design consists of two 90-degree magnetic dipoles, complemented by electrostatic quadrupoles, sextupoles, and a multipole, arranged in a symmetric configuration to minimize aberrations. A detailed description of the design and results of extensive simulations are given.

  2. Moderate resolution spectrophotometry of high redshift quasars

    Science.gov (United States)

    Schneider, Donald P.; Schmidt, Maarten; Gunn, James E.

    1991-01-01

    A uniform set of photometry and high signal-to-noise moderate resolution spectroscopy of 33 quasars with redshifts larger than 3.1 is presented. The sample consists of 17 newly discovered quasars (two with redshifts in excess of 4.4) and 16 sources drawn from the literature. The objects in this sample have r magnitudes between 17.4 and 21.4; their luminosities range from -28.8 to -24.9. Three of the 33 objects are broad absorption line quasars. A number of possible high redshift damped Ly-alpha systems were found.

  3. Radiation length imaging with high resolution telescopes

    CERN Document Server

    Stolzenberg, U; Schwenker, B; Wieduwilt, P; Marinas, C; Lütticke, F

    2016-01-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length $X$/$X_0$ profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D images of the radiation length of thin planar objects. At the heart of the $X$/$X_0$ imaging is a spatially resolved measurement of the scattering angles of particles traversing the object under study. The main challenges are the alignment of the reference telescope and the calibration of its angular resolution. In order to demonstrate the capabilities of $X$/$X_0$ imaging, a test beam experiment has been conducted. The devices under test were two mechanical prototype modules of the Belle II vertex detector. A data sample of ...

  4. High Resolution Bathymetry Estimation Improvement with Single ImageSuper Resolution Algorithm Super Resolution Forests

    Science.gov (United States)

    2017-01-26

    process of the SRF algorithm, we were able to further increase the mean PSNR score of the high resolution estimated data from previously used bicubic...This meant that implementing the edited variance before the bicubic estimates were created caused the mean PSNR to increase the most, and all...interpolation (by about 1 dB). Figure 7: PSNR comparison (with mean scores) between Bicubic Interpolation and SRF Figure 7 shows the comparison between

  5. High-time Resolution Astrophysics and Pulsars

    CERN Document Server

    Shearer, Andy

    2008-01-01

    The discovery of pulsars in 1968 heralded an era where the temporal characteristics of detectors had to be reassessed. Up to this point detector integration times would normally be measured in minutes rather seconds and definitely not on sub-second time scales. At the start of the 21st century pulsar observations are still pushing the limits of detector telescope capabilities. Flux variations on times scales less than 1 nsec have been observed during giant radio pulses. Pulsar studies over the next 10 to 20 years will require instruments with time resolutions down to microseconds and below, high-quantum quantum efficiency, reasonable energy resolution and sensitive to circular and linear polarisation of stochastic signals. This chapter is review of temporally resolved optical observations of pulsars. It concludes with estimates of the observability of pulsars with both existing telescopes and into the ELT era.

  6. Novel high-resolution VGA QWIP detector

    Science.gov (United States)

    Kataria, H.; Asplund, C.; Lindberg, A.; Smuk, S.; Alverbro, J.; Evans, D.; Sehlin, S.; Becanovic, S.; Tinghag, P.; Höglund, L.; Sjöström, F.; Costard, E.

    2017-02-01

    Continuing with its legacy of producing high performance infrared detectors, IRnova introduces its high resolution LWIR IDDCA (Integrated Detector Dewar Cooler assembly) based on QWIP (quantum well infrared photodetector) technology. The Focal Plane Array (FPA) has 640×512 pixels, with small (15μm) pixel pitch, and is based on the FLIRIndigo ISC0403 Readout Integrated Circuit (ROIC). The QWIP epitaxial structures are grown by metal-organic vapor phase epitaxy (MOVPE) at IRnova. Detector stability and response uniformity inherent to III/V based material will be demonstrated in terms of high performing detectors. Results showing low NETD at high frame rate will be presented. This makes it one of the first 15μm pitch QWIP based LWIR IDDCA commercially available on the market. High operability and stability of our other QWIP based products will also be shared.

  7. Extension of least squares spectral resolution algorithm to high-resolution lipidomics data.

    Science.gov (United States)

    Zeng, Ying-Xu; Mjøs, Svein Are; David, Fabrice P A; Schmid, Adrien W

    2016-03-31

    Lipidomics, which focuses on the global study of molecular lipids in biological systems, has been driven tremendously by technical advances in mass spectrometry (MS) instrumentation, particularly high-resolution MS. This requires powerful computational tools that handle the high-throughput lipidomics data analysis. To address this issue, a novel computational tool has been developed for the analysis of high-resolution MS data, including the data pretreatment, visualization, automated identification, deconvolution and quantification of lipid species. The algorithm features the customized generation of a lipid compound library and mass spectral library, which covers the major lipid classes such as glycerolipids, glycerophospholipids and sphingolipids. Next, the algorithm performs least squares resolution of spectra and chromatograms based on the theoretical isotope distribution of molecular ions, which enables automated identification and quantification of molecular lipid species. Currently, this methodology supports analysis of both high and low resolution MS as well as liquid chromatography-MS (LC-MS) lipidomics data. The flexibility of the methodology allows it to be expanded to support more lipid classes and more data interpretation functions, making it a promising tool in lipidomic data analysis.

  8. High-Temporal-Resolution High-Spatial-Resolution Spaceborne SAR Based on Continuously Varying PRF.

    Science.gov (United States)

    Men, Zhirong; Wang, Pengbo; Li, Chunsheng; Chen, Jie; Liu, Wei; Fang, Yue

    2017-07-25

    Synthetic Aperture Radar (SAR) is a well-established and powerful imaging technique for acquiring high-spatial-resolution images of the Earth's surface. With the development of beam steering techniques, sliding spotlight and staring spotlight modes have been employed to support high-spatial-resolution applications. In addition to this strengthened high-spatial-resolution and wide-swath capability, high-temporal-resolution (short repeat-observation interval) represents a key capability for numerous applications. However, conventional SAR systems are limited in that the same patch can only be illuminated for several seconds within a single pass. This paper considers a novel high-squint-angle system intended to acquire high-spatial-resolution spaceborne SAR images with repeat-observation intervals varying from tens of seconds to several minutes within a single pass. However, an exponentially increased range cell migration would arise and lead to a conflict between the receive window and 'blind ranges'. An efficient data acquisition technique for high-temporal-resolution, high-spatial-resolution and high-squint-angle spaceborne SAR, in which the pulse repetition frequency (PRF) is continuously varied according to the changing slant range, is presented in this paper. This technique allows echo data to remain in the receive window instead of conflicting with the transmitted pulse or nadir echo. Considering the precision of hardware, a compromise and practical strategy is also proposed. Furthermore, a detailed performance analysis of range ambiguities is provided with respect to parameters of TerraSAR-X. For strong point-like targets, the range ambiguity of this technique would be better than that of uniform PRF technique. For this innovative technique, a resampling strategy and modified imaging algorithm have been developed to handle the non-uniformly sampled echo data. Simulations are performed to validate the efficiency of the proposed technique and the associated

  9. Cheetah: A high frame rate, high resolution SWIR image camera

    Science.gov (United States)

    Neys, Joel; Bentell, Jonas; O'Grady, Matt; Vermeiren, Jan; Colin, Thierry; Hooylaerts, Peter; Grietens, Bob

    2008-10-01

    A high resolution, high frame rate InGaAs based image sensor and associated camera has been developed. The sensor and the camera are capable of recording and delivering more than 1700 full 640x512pixel frames per second. The FPA utilizes a low lag CTIA current integrator in each pixel, enabling integration times shorter than one microsecond. On-chip logics allows for four different sub windows to be read out simultaneously at even higher rates. The spectral sensitivity of the FPA is situated in the SWIR range [0.9-1.7 μm] and can be further extended into the Visible and NIR range. The Cheetah camera has max 16 GB of on-board memory to store the acquired images and transfer the data over a Gigabit Ethernet connection to the PC. The camera is also equipped with a full CameralinkTM interface to directly stream the data to a frame grabber or dedicated image processing unit. The Cheetah camera is completely under software control.

  10. High-resolution EEG (HR-EEG) and magnetoencephalography (MEG).

    Science.gov (United States)

    Gavaret, M; Maillard, L; Jung, J

    2015-03-01

    High-resolution EEG (HR-EEG) and magnetoencephalography (MEG) allow the recording of spontaneous or evoked electromagnetic brain activity with excellent temporal resolution. Data must be recorded with high temporal resolution (sampling rate) and high spatial resolution (number of channels). Data analyses are based on several steps with selection of electromagnetic signals, elaboration of a head model and use of algorithms in order to solve the inverse problem. Due to considerable technical advances in spatial resolution, these tools now represent real methods of ElectroMagnetic Source Imaging. HR-EEG and MEG constitute non-invasive and complementary examinations, characterized by distinct sensitivities according to the location and orientation of intracerebral generators. In the presurgical assessment of drug-resistant partial epilepsies, HR-EEG and MEG can characterize and localize interictal activities and thus the irritative zone. HR-EEG and MEG often yield significant additional data that are complementary to other presurgical investigations and particularly relevant in MRI-negative cases. Currently, the determination of the epileptogenic zone and functional brain mapping remain rather less well-validated indications. In France, in 2014, HR-EEG is now part of standard clinical investigation of epilepsy, while MEG remains a research technique.

  11. Integrated High Resolution Monitoring of Mediterranean vegetation

    Science.gov (United States)

    Cesaraccio, Carla; Piga, Alessandra; Ventura, Andrea; Arca, Angelo; Duce, Pierpaolo; Mereu, Simone

    2017-04-01

    The study of the vegetation features in a complex and highly vulnerable ecosystems, such as Mediterranean maquis, leads to the need of using continuous monitoring systems at high spatial and temporal resolution, for a better interpretation of the mechanisms of phenological and eco-physiological processes. Near-surface remote sensing techniques are used to quantify, at high temporal resolution, and with a certain degree of spatial integration, the seasonal variations of the surface optical and radiometric properties. In recent decades, the design and implementation of global monitoring networks involved the use of non-destructive and/or cheaper approaches such as (i) continuous surface fluxes measurement stations, (ii) phenological observation networks, and (iii) measurement of temporal and spatial variations of the vegetation spectral properties. In this work preliminary results from the ECO-SCALE (Integrated High Resolution Monitoring of Mediterranean vegetation) project are reported. The project was manly aimed to develop an integrated system for environmental monitoring based on digital photography, hyperspectral radiometry , and micrometeorological techniques during three years of experimentation (2013-2016) in a Mediterranean site of Italy (Capo Caccia, Alghero). The main results concerned the analysis of chromatic coordinates indices from digital images, to characterized the phenological patterns for typical shrubland species, determining start and duration of the growing season, and the physiological status in relation to different environmental drought conditions; then the seasonal patterns of canopy phenology, was compared to NEE (Net Ecosystem Exchange) patterns, showing similarities. However, maximum values of NEE and ER (Ecosystem respiration), and short term variation, seemed mainly tuned by inter annual pattern of meteorological variables, in particular of temperature recorded in the months preceding the vegetation green-up. Finally, green signals

  12. High-resolution phylogenetic microbial community profiling

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Esther; Coleman-Derr, Devin; Bowman, Brett; Schwientek, Patrick; Clum, Alicia; Copeland, Alex; Ciobanu, Doina; Cheng, Jan-Fang; Gies, Esther; Hallam, Steve; Tringe, Susannah; Woyke, Tanja

    2014-03-17

    The representation of bacterial and archaeal genome sequences is strongly biased towards cultivated organisms, which belong to merely four phylogenetic groups. Functional information and inter-phylum level relationships are still largely underexplored for candidate phyla, which are often referred to as microbial dark matter. Furthermore, a large portion of the 16S rRNA gene records in the GenBank database are labeled as environmental samples and unclassified, which is in part due to low read accuracy, potential chimeric sequences produced during PCR amplifications and the low resolution of short amplicons. In order to improve the phylogenetic classification of novel species and advance our knowledge of the ecosystem function of uncultivated microorganisms, high-throughput full length 16S rRNA gene sequencing methodologies with reduced biases are needed. We evaluated the performance of PacBio single-molecule real-time (SMRT) sequencing in high-resolution phylogenetic microbial community profiling. For this purpose, we compared PacBio and Illumina metagenomic shotgun and 16S rRNA gene sequencing of a mock community as well as of an environmental sample from Sakinaw Lake, British Columbia. Sakinaw Lake is known to contain a large age of microbial species from candidate phyla. Sequencing results show that community structure based on PacBio shotgun and 16S rRNA gene sequences is highly similar in both the mock and the environmental communities. Resolution power and community representation accuracy from SMRT sequencing data appeared to be independent of GC content of microbial genomes and was higher when compared to Illumina-based metagenome shotgun and 16S rRNA gene (iTag) sequences, e.g. full-length sequencing resolved all 23 OTUs in the mock community, while iTags did not resolve closely related species. SMRT sequencing hence offers various potential benefits when characterizing uncharted microbial communities.

  13. Novel high resolution tactile robotic fingertips

    DEFF Research Database (Denmark)

    Drimus, Alin; Jankovics, Vince; Gorsic, Matija

    2014-01-01

    This paper describes a novel robotic fingertip based on piezoresistive rubber that can sense pressure tactile stimuli with a high spatial resolution over curved surfaces. The working principle is based on a three-layer sandwich structure (conductive electrodes on top and bottom and piezoresistive...... with specialized data acquisition electronics that acquire 500 frames per second provides rich information regarding contact force, shape and angle for bio- inspired robotic fingertips. Furthermore, a model of estimating the force of contact based on values of the cells is proposed....

  14. Operating mode of high pressure straws with high spatial resolution

    CERN Document Server

    Davkov, K I; Peshekhonov, V D; Cholakov, V D

    2013-01-01

    The article presents results of studying the operating mode of thin-walled drift tubes (straws) at flushing it with a high-pressure gas mixture, which allowed obtaining extremely high spatial resolution for straw detectors. The results of studying the radiation ageing of straws operating in this mode are also described.

  15. Crusta: Visualizing High-resolution Global Data

    Science.gov (United States)

    Bernardin, T. S.; Kreylos, O.; Bowles, C. J.; Cowgill, E.; Hamann, B.; Kellogg, L. H.

    2009-12-01

    Virtual globes have become indispensable tools for visualizing, understanding and presenting data from Earth and other planetary bodies. The scientific community has invested much effort into exploiting existing globes to their fullest potential by refining and adapting their capabilities to better satisfy specific needs. For example, Google Earth provides users with the ability to view hillshade images derived from airborne LiDAR data such as the 2007 Northern California GeoEarthScope data. However, because most available globes were not designed with the specific needs of geoscientists in mind, shortcomings are becoming increasingly evident in geoscience applications such as terrain visualization. In particular, earth scientists struggle to visualize digital elevation models with both high spatial resolution (0.5 - 1 square meters per sample) and large extent (>2000 square kilometers), such as those obtained with airborne LiDAR. To address the specific earth science need of real-time terrain visualization of LiDAR data, we are developing Crusta as part of a close collaboration involving earth and computer scientists. Crusta is a new virtual globe that differs from widely used globes by both providing accurate global data representation and the ability to easily visualize custom topographic and image data. As a result, Crusta enables real-time, interactive visualization of high resolution digital elevation data spanning thousands of square kilometers, such as the complete 2007 Northern California GeoEarthScope airborne LiDAR data set. To implement an accurate data representation and avoid distortion of the display at the poles, where other projections have singularities, Crusta represents the globe as a thirty-sided polyhedron. Each side of this polyhedron can be subdivided to an arbitrarily fine grid on the surface of the globe, which allows Crusta to accommodate input data of arbitrary resolution ranging from global (e.g., Blue Marble) to local (e.g., a tripod

  16. High-resolution noncontact atomic force microscopy.

    Science.gov (United States)

    Pérez, Rubén; García, Ricardo; Schwarz, Udo

    2009-07-01

    original papers authored by many of the leading groups in the field with the goal of providing a well-balanced overview on the state-of-the-art in this rapidly evolving field. These papers, many of which are based on notable presentations given during the Madrid conference, feature highlights such as (1) the development of sophisticated force spectroscopy procedures that are able to map the complete 3D tip-sample force field on different surfaces; (2) the considerable resolution improvement of Kelvin probe force microscopy (reaching, in some cases, the atomic scale), which is accompanied by a thorough, quantitative understanding of the contrast observed; (3) the perfecting of atomic resolution imaging on insulating substrates, which helps reshape our microscopic understanding of surface properties and chemical activity of these surfaces; (4) the description of instrumental and methodological developments that pave the way to the atomic-scale characterization of magnetic and electronic properties of nanostructures, and last but not least (5) the extension of dynamic imaging modes to high-resolution operation in liquids, ultimately achieving atomic resolution. The latter developments are already having a significant impact in the highly competitive field of biological imaging under physiological conditions. This special issue of Nanotechnology would not have been possible without the highly professional support from Nina Couzin, Amy Harvey, Alex Wotherspoon and the entire Nanotechnology team at IOP Publishing. We are thankful for their help in pushing this project forward. We also thank the authors who have contributed their excellent original articles to this issue, the referees whose comments have helped make the issue an accurate portrait of this rapidly moving field, and the entire NC-AFM community that continues to drive NC-AFM to new horizons.

  17. Principles of high resolution NMR in solids

    CERN Document Server

    Mehring, Michael

    1983-01-01

    The field of Nuclear Magnetic Resonance (NMR) has developed at a fascinating pace during the last decade. It always has been an extremely valuable tool to the organic chemist by supplying molecular "finger print" spectra at the atomic level. Unfortunately the high resolution achievable in liquid solutions could not be obtained in solids and physicists and physical chemists had to live with unresolved lines open to a wealth of curve fitting procedures and a vast amount of speculations. High resolution NMR in solids seemed to be a paradoxon. Broad structure­ less lines are usually encountered when dealing with NMR in solids. Only with the recent advent of mUltiple pulse, magic angle, cross-polarization, two-dimen­ sional and multiple-quantum spectroscopy and other techniques during the last decade it became possible to resolve finer details of nuclear spin interactions in solids. I have felt that graduate students, researchers and others beginning to get involved with these techniques needed a book which trea...

  18. Limiting liability via high resolution image processing

    Energy Technology Data Exchange (ETDEWEB)

    Greenwade, L.E.; Overlin, T.K.

    1996-12-31

    The utilization of high resolution image processing allows forensic analysts and visualization scientists to assist detectives by enhancing field photographs, and by providing the tools and training to increase the quality and usability of field photos. Through the use of digitized photographs and computerized enhancement software, field evidence can be obtained and processed as `evidence ready`, even in poor lighting and shadowed conditions or darkened rooms. These images, which are most often unusable when taken with standard camera equipment, can be shot in the worst of photographic condition and be processed as usable evidence. Visualization scientists have taken the use of digital photographic image processing and moved the process of crime scene photos into the technology age. The use of high resolution technology will assist law enforcement in making better use of crime scene photography and positive identification of prints. Valuable court room and investigation time can be saved and better served by this accurate, performance based process. Inconclusive evidence does not lead to convictions. Enhancement of the photographic capability helps solve one major problem with crime scene photos, that if taken with standard equipment and without the benefit of enhancement software would be inconclusive, thus allowing guilty parties to be set free due to lack of evidence.

  19. High-Resolution Scintimammography: A Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    Rachel F. Brem; Joelle M. Schoonjans; Douglas A. Kieper; Stan Majewski; Steven Goodman; Cahid Civelek

    2002-07-01

    This study evaluated a novel high-resolution breast-specific gamma camera (HRBGC) for the detection of suggestive breast lesions. Methods: Fifty patients (with 58 breast lesions) for whom a scintimammogram was clinically indicated were prospectively evaluated with a general-purpose gamma camera and a novel HRBGC prototype. The results of conventional and high-resolution nuclear studies were prospectively classified as negative (normal or benign) or positive (suggestive or malignant) by 2 radiologists who were unaware of the mammographic and histologic results. All of the included lesions were confirmed by pathology. Results: There were 30 benign and 28 malignant lesions. The sensitivity for detection of breast cancer was 64.3% (18/28) with the conventional camera and 78.6% (22/28) with the HRBGC. The specificity with both systems was 93.3% (28/30). For the 18 nonpalpable lesions, sensitivity was 55.5% (10/18) and 72.2% (13/18) with the general-purpose camera and the HRBGC, respectively. For lesions 1 cm, 7 of 15 were detected with the general-purpose camera and 10 of 15 with the HRBGC. Four lesions (median size, 8.5 mm) were detected only with the HRBGC and were missed by the conventional camera. Conclusion: Evaluation of indeterminate breast lesions with an HRBGC results in improved sensitivity for the detection of cancer, with greater improvement shown for nonpalpable and 1-cm lesions.

  20. High-resolution light microscopy of nanoforms

    Science.gov (United States)

    Vodyanoy, Vitaly; Pustovyy, Oleg; Vainrub, Arnold

    2007-09-01

    We developed a high resolution light imaging system. Diffraction gratings with 100 nm width lines as well as less than 100 nm size features of different-shaped objects are clearly visible on a calibrated microscope test slide (Vainrub et al., Optics Letters, 2006, 31, 2855). The two-point resolution increase results from a known narrowing of the central diffraction peak for the annular aperture. Better visibility and advanced contrast of the smallest features in the image are due to enhancement of high spatial frequencies in the optical transfer function. The imaging system is portable, low energy, and battery operated. It has been adapted to use in both transmitting and reflecting light. It is particularly applicable for motile nanoform systems where structure and functions can be depicted in real time. We have isolated micrometer and submicrometer particles, termed proteons, from human and animal blood. Proteons form by reversible seeded aggregation of proteins around proteon nucleating centers (PNCs). PNCs are comprised of 1-2nm metallic nanoclusters containing 40-300 atoms. Proteons are capable of spontaneous assembling into higher nanoform systems assuming structure of complicated topology. The arrangement of complex proteon system mimics the structure of a small biological cell. It has structures that imitate membrane and nucleolus or nuclei. Some of these nanoforms are motile. They interact and divide. Complex nanoform systems can spontaneously reduce to simple proteons. The physical properties of these nanoforms could shed some light on the properties of early life forms or forms at extreme conditions.

  1. Ultra-high resolution and high-brightness AMOLED

    Science.gov (United States)

    Wacyk, Ihor; Ghosh, Amal; Prache, Olivier; Draper, Russ; Fellowes, Dave

    2012-06-01

    As part of its continuing effort to improve both the resolution and optical performance of AMOLED microdisplays, eMagin has recently developed an SXGA (1280×3×1024) microdisplay under a US Army RDECOM CERDEC NVESD contract that combines the world's smallest OLED pixel pitch with an ultra-high brightness green OLED emitter. This development is aimed at next-generation HMD systems with "see-through" and daylight imaging requirements. The OLED pixel array is built on a 0.18-micron CMOS backplane and contains over 4 million individually addressable pixels with a pixel pitch of 2.7 × 8.1 microns, resulting in an active area of 0.52 inches diagonal. Using both spatial and temporal enhancement, the display can provide over 10-bits of gray-level control for high dynamic range applications. The new pixel design also enables the future implementation of a full-color QSXGA (2560 × RGB × 2048) microdisplay in an active area of only 1.05 inch diagonal. A low-power serialized low-voltage-differential-signaling (LVDS) interface is integrated into the display for use as a remote video link for tethered systems. The new SXGA backplane has been combined with the high-brightness green OLED device developed by eMagin under an NVESD contract. This OLED device has produced an output brightness of more than 8000fL with all pixels on; lifetime measurements are currently underway and will presented at the meeting. This paper will describe the operational features and first optical and electrical test results of the new SXGA demonstrator microdisplay.

  2. Venus gravity - A high-resolution map

    Science.gov (United States)

    Reasenberg, R. D.; Goldberg, Z. M.; Macneil, P. E.; Shapiro, I. I.

    1981-01-01

    The Doppler data from the radio tracking of the Pioneer Venus Orbiter (PVO) have been used in a two-stage analysis to develop a high-resolution map of the gravitational potential of Venus, represented by a central mass and a surface mass density. The two-stage procedure invokes a Kalman filter-smoother to determine the orbit of the spacecraft, and a stabilized linear inverter to estimate the surface mass density. The resultant gravity map is highly correlated with the topographic map derived from the PVO radar altimeter data. However, the magnitudes of the gravity variations are smaller than would be expected if the topography were uncompensated, indicating that at least partial compensation has taken place.

  3. Ultra-high resolution computed tomography imaging

    Energy Technology Data Exchange (ETDEWEB)

    Paulus, Michael J. (Knoxville, TN); Sari-Sarraf, Hamed (Knoxville, TN); Tobin, Jr., Kenneth William (Harriman, TN); Gleason, Shaun S. (Knoxville, TN); Thomas, Jr., Clarence E. (Knoxville, TN)

    2002-01-01

    A method for ultra-high resolution computed tomography imaging, comprising the steps of: focusing a high energy particle beam, for example x-rays or gamma-rays, onto a target object; acquiring a 2-dimensional projection data set representative of the target object; generating a corrected projection data set by applying a deconvolution algorithm, having an experimentally determined a transfer function, to the 2-dimensional data set; storing the corrected projection data set; incrementally rotating the target object through an angle of approximately 180.degree., and after each the incremental rotation, repeating the radiating, acquiring, generating and storing steps; and, after the rotating step, applying a cone-beam algorithm, for example a modified tomographic reconstruction algorithm, to the corrected projection data sets to generate a 3-dimensional image. The size of the spot focus of the beam is reduced to not greater than approximately 1 micron, and even to not greater than approximately 0.5 microns.

  4. Concept for a new high resolution high intensity diffractometer

    Energy Technology Data Exchange (ETDEWEB)

    Stuhr, U. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    A concept of a new time-of-flight powder-diffractometer for a thermal neutral beam tube at SINQ is presented. The design of the instrument optimises the contradictory conditions of high intensity and high resolution. The high intensity is achieved by using many neutron pulses simultaneously. By analysing the time-angle-pattern of the detected neutrons an assignment of the neutrons to a single pulse is possible. (author) 3 figs., tab., refs.

  5. High-Resolution Differential Thermography of Semiconductor Edifices

    Directory of Open Access Journals (Sweden)

    Vera Marie Sastine

    2004-12-01

    Full Text Available We develop a cost-effective, high-resolution, and noninvasive imaging technique for thermal mapping of semiconductor edifices in integrated circuits. Initial implementation was done using a power-stabilized optical feedback laser system that detects changes in the optical beam-induced current when the package temperature of the device is increased. The linear change in detected current can be translated to a thermal gradient, which can reveal semiconductor “hotspots”—localized sites with anomalous thermal activity. These locales are possible fault sites or areas susceptible to defects, which are the best jump-off points for failure analysis.

  6. High-resolution infrared observations of active galactic nuclei

    Science.gov (United States)

    Pott, Jörg-Uwe

    2012-07-01

    Interferometric resolution at IR wavelengths offers for the first time the possibility to zoom into the nuclei of galaxies beyond the circumnuclear stellar structures and spatially resolve gas and dust in the innermost regions (0.05-5pc), dominated by the central black hole. Ultimate goal is to reveal new aspects of AGN feeding, and interaction with its host galaxy. After first successes of resolving AGN with infrared interferometry (VLTI, Keck-IF), the second generation of high-resolution interferometric imagers behind 8m class telescopes is currently being built. I will summarize current aspects and successes of the field, and present our activities to provide extended capabilities for VLTI-Midi and -Matisse, LBT-Linc-Nirvana and Keck-Astra to study a larger sample of AGN in greater detail.

  7. High-resolution colorimetric imaging of paintings

    Science.gov (United States)

    Martinez, Kirk; Cupitt, John; Saunders, David R.

    1993-05-01

    With the aim of providing a digital electronic replacement for conventional photography of paintings, a scanner has been constructed based on a 3000 X 2300 pel resolution camera which is moved precisely over a 1 meter square area. Successive patches are assembled to form a mosaic which covers the whole area at c. 20 pels/mm resolution, which is sufficient to resolve the surface textures, particularly craquelure. To provide high color accuracy, a set of seven broad-band interference filters are used to cover the visible spectrum. A calibration procedure based upon a least-mean-squares fit to the color of patches from a Macbeth Colorchecker chart yields an average color accuracy of better than 3 units in the CMC uniform color space. This work was mainly carried out as part of the VASARI project funded by the European Commission's ESPRIT program, involving companies and galleries from around Europe. The system is being used to record images for conservation research, for archival purposes and to assist in computer-aided learning in the field of art history. The paper will describe the overall system design, including the selection of the various hardware components and the design of controlling software. The theoretical basis for the color calibration methodology is described as well as the software for its practical implementation. The mosaic assembly procedure and some of the associated image processing routines developed are described. Preliminary results from the research will be presented.

  8. High resolution CT of temporal bone trauma

    Energy Technology Data Exchange (ETDEWEB)

    Youn, Eun Kyung [Korea General Hospital, Seoul (Korea, Republic of)

    1986-10-15

    Radiographic studies of the temporal bone following head trauma are indicated when there is cerebrospinal fluid otorrhea or rhinorrhoea, hearing loss, or facial nerve paralysis. Plain radiography displays only 17-30% of temporal bone fractures and pluridirectional tomography is both difficult to perform, particularly in the acutely ill patient, and less satisfactory for the demonstration of fine fractures. Consequently, high resolution CT is the imaging method of choice for the investigation of suspected temporal bone trauma and allows special resolution of fine bony detail comparable to that attainable by conventional tomography. Eight cases of temporal bone trauma examined at Korea General Hospital April 1985 through May 1986. The results were as follows: Seven patients (87%) suffered longitudinal fractures. In 6 patients who had purely conductive hearing loss, CT revealed various ossicular chain abnormality. In one patient who had neuro sensory hearing loss, CT demonstrated intract ossicular with a fracture nearing lateral wall of the lateral semicircular canal. In one patient who had mixed hearing loss, CT showed complex fracture.

  9. Pyramidal fractal dimension for high resolution images

    Science.gov (United States)

    Mayrhofer-Reinhartshuber, Michael; Ahammer, Helmut

    2016-07-01

    Fractal analysis (FA) should be able to yield reliable and fast results for high-resolution digital images to be applicable in fields that require immediate outcomes. Triggered by an efficient implementation of FA for binary images, we present three new approaches for fractal dimension (D) estimation of images that utilize image pyramids, namely, the pyramid triangular prism, the pyramid gradient, and the pyramid differences method (PTPM, PGM, PDM). We evaluated the performance of the three new and five standard techniques when applied to images with sizes up to 8192 × 8192 pixels. By using artificial fractal images created by three different generator models as ground truth, we determined the scale ranges with minimum deviations between estimation and theory. All pyramidal methods (PM) resulted in reasonable D values for images of all generator models. Especially, for images with sizes ≥1024 ×1024 pixels, the PMs are superior to the investigated standard approaches in terms of accuracy and computation time. A measure for the possibility to differentiate images with different intrinsic D values did show not only that the PMs are well suited for all investigated image sizes, and preferable to standard methods especially for larger images, but also that results of standard D estimation techniques are strongly influenced by the image size. Fastest results were obtained with the PDM and PGM, followed by the PTPM. In terms of absolute D values best performing standard methods were magnitudes slower than the PMs. Concluding, the new PMs yield high quality results in short computation times and are therefore eligible methods for fast FA of high-resolution images.

  10. High-resolution Imaging Techniques for the Assessment of Osteoporosis

    Science.gov (United States)

    Krug, Roland; Burghardt, Andrew J.; Majumdar, Sharmila; Link, Thomas M.

    2010-01-01

    Synopsis The importance of assessing the bone’s microarchitectural make-up in addition to its mineral density in the context of osteoporosis has been emphasized in a number of publications. The high spatial resolution required to resolve the bone’s microstructure in a clinically feasible scan time is challenging. Currently, the best suited modalities meeting these requirements in vivo are high-resolution peripheral quantitative imaging (HR-pQCT) and magnetic resonance imaging (MRI). Whereas HR-pQCT is limited to peripheral skeleton regions like the wrist and ankle, MRI can also image other sites like the proximal femur but usually with lower spatial resolution. In addition Multidetector-CT has been used for high-resolution imaging of trabecular bone structure, however, the radiation dose is a limiting factor. This article provides an overview of the different modalities, technical requirements and recent developments in this emerging field. Details regarding imaging protocols as well as image post-processing methods for bone structure quantification are discussed. PMID:20609895

  11. Detection of proximal caries with high-resolution and standard resolution digital radiographic systems

    NARCIS (Netherlands)

    Berkhout, W.E.R.; Verheij, H.G.C.; Syriopoulos, K.; Li, G.; Sanderink, G.C.H.; van der Stelt, P.F.

    2007-01-01

    Aims: The aim of this study was to: (1) compare the diagnostic accuracy of the high-resolution and standard resolution settings of four digital imaging systems for caries diagnosis and (2) compare the effect on the diagnostic accuracy of reducing the high-resolution image sizes to the standard

  12. Current barriers to confine high frequency common mode currents

    NARCIS (Netherlands)

    Moonen, Dominicus Johannes Guilielmus; Buesink, Frederik Johannes Karel; Leferink, Frank Bernardus Johannes

    2016-01-01

    A commercially produced three phase power line filter is submitted to a Current Barrier (CB) Electro-Magnetic Compatibility (EMC) zoning strategy as an attempt to confine high frequency common mode currents. The intent of the paper is not to show how to build a ’perfect’ filter, since this is known.

  13. Improved methods for high resolution electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, J.R.

    1987-04-01

    Existing methods of making support films for high resolution transmission electron microscopy are investigated and novel methods are developed. Existing methods of fabricating fenestrated, metal reinforced specimen supports (microgrids) are evaluated for their potential to reduce beam induced movement of monolamellar crystals of C/sub 44/H/sub 90/ paraffin supported on thin carbon films. Improved methods of producing hydrophobic carbon films by vacuum evaporation, and improved methods of depositing well ordered monolamellar paraffin crystals on carbon films are developed. A novel technique for vacuum evaporation of metals is described which is used to reinforce microgrids. A technique is also developed to bond thin carbon films to microgrids with a polymer bonding agent. Unique biochemical methods are described to accomplish site specific covalent modification of membrane proteins. Protocols are given which covalently convert the carboxy terminus of papain cleaved bacteriorhodopsin to a free thiol. 53 refs., 19 figs., 1 tab.

  14. A new high-resolution TOF technology

    CERN Document Server

    Fonte, Paulo J R; Williams, M C S

    2000-01-01

    In the framework of the ALICE collaboration we have recently studied the performance of multigap Resistive Plate Chambers operated in avalanche mode and at atmospheric pressure for time-of-flight measurements. The detector provided an overall (detector plus electronics) timing accuracy of 120 ps sigma at an efficiency of 98% for MIPs. The chambers had 4 gas gaps of 0.3 mm, each limited by a metallised ceramic plate and a glass plate, with an active dimension of 4'4cm2. The gas mixture contained C2H2F4+5%isobutane+10%SF6. A few percent of streamer discharges, each releasing about 20 pC, was tolerated without any noticeable inconvenience. This detector opens perspectives of affordable and reliable high granularity large area TOF detectors, with an efficiency and a time resolution comparable to existing scintillator-based TOF technology but with significantly, up to an order of magnitude, lower price per channel.

  15. Capillary detectors for high resolution tracking

    CERN Document Server

    Annis, P

    1997-01-01

    We present a new tracking device based on glass capillary bundles or layers filled with highly purified liquid scintillator and read out at one end by means of image intensifiers and CCD devices. A large-volume prototype consisting of 5 × 105 capillaries with a diameter of 20 μm and a length of 180 cm and read out by a megapixel CCD has been tested with muon and neutrino beams at CERN. With this prototype a two track resolution of 33 μm was achieved with passing through muons. Images of neutrino interactions in a capillary bundle have also been acquired and analysed. Read-out chains based on Electron Bombarded CCD (EBCCD) and image pipeline devices are also investigated. Preliminary results obtained with a capillary bundle read out by an EBCCD are presented.

  16. Speleothems as high-resolution paleoflood archives

    Science.gov (United States)

    Denniston, Rhawn F.; Luetscher, Marc

    2017-08-01

    Over the last two decades, speleothems have become widely utilized records of past environmental variability, typically through their stable isotopic and trace elemental chemistry. Numerous speleothem researchers have identified evidence of flooding recorded by detrital layers trapped within speleothems, but few studies have developed paleoflood reconstructions from such samples. Because they can be precisely dated, are generally immune to post-depositional distortion or erosion, and can be tied to a fixed elevational baseline, speleothems hold enormous potential as high-resolution archives of cave floods, and thus as proxies for extreme rainfall or other hydrologic drivers of cave flooding. Here we review speleothem-based paleoflood reconstruction methods, identify potential biases and pitfalls, and suggest standard practices for future studies.

  17. High-resolution CT of otosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Dewen, Yang; Kodama, Takao; Tono, Tetsuya; Ochiai, Reiji; Kiyomizu, Kensuke; Suzuki, Yukiko; Yano, Takanori; Watanabe, Katsushi [Miyazaki Medical Coll., Kiyotake (Japan)

    1997-11-01

    High-resolution CT (HRCT) scans of thirty-two patients (60 ears) with the clinical diagnosis of fenestral otosclerosis were evaluated retrospectively. HRCT was performed with 1-mm-thick targeted sections and 1-mm (36 ears) or 0.5-mm (10 ears) intervals in the semiaxial projection. Seven patients (14 ears) underwent helical scanning with a 1-mm slice thickness and 1-mm/sec table speed. Forty-five ears (75%) were found to have one or more otospongiotic or otosclerotic foci on HRCT. In most instances (30 ears), the otospongiotic foci were found in the region of the fissula ante fenestram. No significant correlations between CT findings and air conduction threshold were observed. We found a significant relationship between lesions of the labyrinthine capsule and sensorineural hearing loss. We conclude that HRCT is a valuable modality for diagnosing otosclerosis, especially when otospongiotic focus is detected. (author)

  18. GRANULOMETRIC MAPS FROM HIGH RESOLUTION SATELLITE IMAGES

    Directory of Open Access Journals (Sweden)

    Catherine Mering

    2011-05-01

    Full Text Available A new method of land cover mapping from satellite images using granulometric analysis is presented here. Discontinuous landscapes such as steppian bushes of semi arid regions and recently growing urban settlements are especially concerned by this study. Spatial organisations of the land cover are quantified by means of the size distribution analysis of the land cover units extracted from high resolution remotely sensed images. A granulometric map is built by automatic classification of every pixel of the image according to the granulometric density inside a sliding neighbourhood. Granulometric mapping brings some advantages over traditional thematic mapping by remote sensing by focusing on fine spatial events and small changes in one peculiar category of the landscape.

  19. High resolution CT of Meckel's cave.

    Science.gov (United States)

    Chui, M; Tucker, W; Hudson, A; Bayer, N

    1985-01-01

    High resolution CT of the parasellar region was carried out in 50 patients studied for suspected pituitary microadenoma, but who showed normal pituitary gland or microadenoma on CT. This control group of patients all showed an ellipsoid low-density area in the posterior parasellar region. Knowledge of the gross anatomy and correlation with metrizamide cisternography suggest that the low density region represents Meckel's cave, rather than just the trigeminal ganglion alone. Though there is considerable variation in the size of Meckel's cave in different patients as well as the two sides of the same patient, the rather constant ellipsoid configuration of the cave in normal subjects will aid in diagnosing small pathological lesions, thereby obviating more invasive cisternography via the transovale or lumbar route. Patients with "idiopathic" tic douloureux do not show a Meckel's cave significantly different from the control group.

  20. Georadar - high resolution geophysical electromagnetic device

    Directory of Open Access Journals (Sweden)

    Janez Stern

    1995-12-01

    Full Text Available Georadar is a high resolution geophysical electromagnetic device that was developed in the first part of the 1980's. In Slovenia it was first tested in 1991 on several objects of economicgeological, geotechnical and hydrogeologic nature.Here its usefulness in karst studied is presented. The first part of the paper deals with description of measurement procedure and methodological bases, and the second part with experience and results of case histories. Shown are radargrams from ornamental stone quarry Hotavlje, calcite mine Stahovica, Golobja jama karstcave near Divača and from highway construction site Razdrto-Čebulovica. All measurements were performed with the georadar instrument Pulse EKKO IV with a lOOMHz antenna according to the method of reflection profiling.

  1. High temperature superconductor current leads

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL); Poeppel, Roger B. (Glen Ellyn, IL)

    1995-01-01

    An electrical lead having one end for connection to an apparatus in a cryogenic environment and the other end for connection to an apparatus outside the cryogenic environment. The electrical lead includes a high temperature superconductor wire and an electrically conductive material distributed therein, where the conductive material is present at the one end of the lead at a concentration in the range of from 0 to about 3% by volume, and at the other end of the lead at a concentration of less than about 20% by volume. Various embodiments are shown for groups of high temperature superconductor wires and sheaths.

  2. Electromigration Issues in High Current Horn

    CERN Document Server

    Zhang, Wu; Hseuh, Brigitte; Sandberg, Jon; Simos, Nikolaos; Tuozzolo, Joseph; Weng, Wu-Tsung

    2005-01-01

    The secondary particle focusing horn for the AGS neutrino experiment proposal is a high current and high current density device. The peak current of horn is 300 kA. At the smallest area of horn, the current density is near 8 kA/mm2. At very high current density, a few kA/mm2, the electromigration phenomena will occur. Momentum transfer between electrons and metal atoms at high current density causes electromigration. The reliability and lifetime of focusing horn can be severely reduced by electromigration. In this paper, we discuss issues such as device reliability model, incubation time of electromigration, and lifetime of horn.

  3. Precision cosmology with time delay lenses: high resolution imaging requirements

    CERN Document Server

    Meng, Xiao-Lei; Agnello, Adriano; Auger, Matthew W; Liao, Kai; Marshall, Philip J

    2015-01-01

    Lens time delays are a powerful probe of cosmology, provided that the gravitational potential of the main deflector can be modeled with sufficient precision. Recent work has shown that this can be achieved by detailed modeling of the host galaxies of lensed quasars, which appear as "Einstein Rings" in high resolution images. We carry out a systematic exploration of the high resolution imaging required to exploit the thousands of lensed quasars that will be discovered by current and upcoming surveys with the next decade. Specifically, we simulate realistic lens systems as imaged by the Hubble Space Telescope (HST), James Webb Space Telescope (JWST), and ground based adaptive optics images taken with Keck or the Thirty Meter Telescope (TMT). We compare the performance of these pointed observations with that of images taken by the Euclid (VIS), Wide-Field Infrared Survey Telescope (WFIRST) and Large Synoptic Survey Telescope (LSST) surveys. We use as our metric the precision with which the slope $\\gamma'$ of the...

  4. Some considerations on the current debate about typing resolution in solid organ transplantation.

    Science.gov (United States)

    Vogiatzi, Paraskevi

    2016-01-01

    The shortage of suitable organs and achieved tolerance are uncontested main concerns in transplantation. Long waiting lists for deceased donors and limited numbers of living donors are the current scenarios. Kidney grafts from living donors have better overall survival compared to cadaveric and require less aggressive immunosuppressive regimens. The human leukocyte antigen (HLA) labs have the key role to test the recipient and donors compatibility based on typing and antibody profile. The current standard molecular procedure in solid organ transplantation is low-resolution typing, at the antigen level. In this commentary, the merits of high versus low degree of typing resolution in solid organ transplantation are discussed. Critical questions and reasons to bring high-resolution typing as a routine test in health system are considered. Specifically, with the introduction of the next-generation sequencing (NGS) in HLA, the pros and cons in living donation and benefits after deceased donation are critically evaluated. NGS has the potential to improve the transplant rates and the overall graft survival. Alternative strategies to increase in demanding the number of transplants are briefly highlighted.

  5. The high resolution neutrino calorimeter KARMEN

    Energy Technology Data Exchange (ETDEWEB)

    Drexlin, G.; Eberhard, V.; Gemmeke, H.; Giorginis, G.; Grandegger, W.; Gumbsheimer, R.; Hucker, H.; Husson, L.; Kleinfeller, J.; Maschuw, R.; Plischke, P.; Spohrer, G.; Schmidt, F.K.; Wochele, J.; Woelfle, S.; Zeitnitz, B. (Kernforschungszentrum Karlsruhe GmbH (Germany, F.R.). Inst. fuer Kernphysik 1 Karlsruhe Univ. (T.H.) (Germany, F.R.). Inst. fuer Experimentelle Kernphysik); Bodman, B.; Burtak, F.; Finckh, E.; Glombik, A.; Kretschmer, W.; Schilling, F.; Voetisch, D. (Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.). Physikalisches Inst.); Edgington, J.A.; Gorringe, T.; Malik, A. (Queen Mary Coll., London (UK)); Booth, N.E. (Oxford Univ. (UK)); Dodd, A.; Payne, A.G.D. (Rutherford Appleton Lab., Chilton (UK))

    1990-04-15

    KARMEN is a 56 t scintillation calorimeter designed for beam dump neutrino experiments at the neutron spallation facility ISIS of the Rutherford Appleton Laboratory. The calorimetric properties are demonstrated by cosmic muons and laser calibration. The measured energy resolution of the detector is {sigma}{sub E}/E{approx equal}11.5%/{radical}E(MeV), the position resolution {sigma}{sub x}=5 cm and the timing resolution {sigma}{sub t}{approx equal}350 ps. (orig.).

  6. High resolution image reconstruction from projection of low resolution images differing in subpixel shifts

    Science.gov (United States)

    Mareboyana, Manohar; Le Moigne, Jacqueline; Bennett, Jerome

    2016-05-01

    In this paper, we demonstrate simple algorithms that project low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithms are very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. are used in projection. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML) algorithms. The algorithms are robust and are not overly sensitive to the registration inaccuracies.

  7. High Resolution Image Reconstruction from Projection of Low Resolution Images DIffering in Subpixel Shifts

    Science.gov (United States)

    Mareboyana, Manohar; Le Moigne-Stewart, Jacqueline; Bennett, Jerome

    2016-01-01

    In this paper, we demonstrate a simple algorithm that projects low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithm is very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. used in projection yield comparable results. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML), and Maximum a posterior (MAP) algorithms. The algorithm is robust and is not overly sensitive to the registration inaccuracies.

  8. High Resolution Airborne Shallow Water Mapping

    Science.gov (United States)

    Steinbacher, F.; Pfennigbauer, M.; Aufleger, M.; Ullrich, A.

    2012-07-01

    In order to meet the requirements of the European Water Framework Directive (EU-WFD), authorities face the problem of repeatedly performing area-wide surveying of all kinds of inland waters. Especially for mid-sized or small rivers this is a considerable challenge imposing insurmountable logistical efforts and costs. It is therefore investigated if large-scale surveying of a river system on an operational basis is feasible by employing airborne hydrographic laser scanning. In cooperation with the Bavarian Water Authority (WWA Weilheim) a pilot project was initiated by the Unit of Hydraulic Engineering at the University of Innsbruck and RIEGL Laser Measurement Systems exploiting the possibilities of a new LIDAR measurement system with high spatial resolution and high measurement rate to capture about 70 km of riverbed and foreland for the river Loisach in Bavaria/Germany and the estuary and parts of the shoreline (about 40km in length) of lake Ammersee. The entire area surveyed was referenced to classic terrestrial cross-section surveys with the aim to derive products for the monitoring and managing needs of the inland water bodies forced by the EU-WFD. The survey was performed in July 2011 by helicopter and airplane and took 3 days in total. In addition, high resolution areal images were taken to provide an optical reference, offering a wide range of possibilities on further research, monitoring, and managing responsibilities. The operating altitude was about 500 m to maintain eye-safety, even for the aided eye, the airspeed was about 55 kts for the helicopter and 75 kts for the aircraft. The helicopter was used in the alpine regions while the fixed wing aircraft was used in the plains and the urban area, using appropriate scan rates to receive evenly distributed point clouds. The resulting point density ranged from 10 to 25 points per square meter. By carefully selecting days with optimum water quality, satisfactory penetration down to the river bed was achieved

  9. Logging Data High-Resolution Sequence Stratigraphy

    Institute of Scientific and Technical Information of China (English)

    Li Hongqi; Xie Yinfu; Sun Zhongchun; Luo Xingping

    2006-01-01

    The recognition and contrast of bed sets in parasequence is difficult in terrestrial basin high-resolution sequence stratigraphy. This study puts forward new methods for the boundary identification and contrast of bed sets on the basis of manifold logging data. The formation of calcareous interbeds, shale resistivity differences and the relation of reservoir resistivity to altitude are considered on the basis of log curve morphological characteristics, core observation, cast thin section, X-ray diffraction and scanning electron microscopy. The results show that the thickness of calcareous interbeds is between 0.5 m and 2 m, increasing on weathering crusts and faults. Calcareous interbeds occur at the bottom of Reservoir resistivity increases with altitude. Calcareous interbeds may be a symbol of recognition for the boundary of bed sets and isochronous contrast bed sets, and shale resistivity differences may confirm the stack relation and connectivity of bed sets. Based on this, a high-rcsolution chronostratigraphic framework of Xi-1 segment in Shinan area, Junggar basin is presented, and the connectivity of bed sets and oil-water contact is confirmed. In this chronostratigraphic framework, the growth order, stack mode and space shape of bed sets are qualitatively and quantitatively described.

  10. High resolution low frequency ultrasonic tomography.

    Science.gov (United States)

    Lasaygues, P; Lefebvre, J P; Mensah, S

    1997-10-01

    Ultrasonic reflection tomography results from a linearization of the inverse acoustic scattering problem, named the inverse Born approximation. The goal of ultrasonic reflection tomography is to obtain reflectivity images from backscattered measurements. This is a Fourier synthesis problem and the first step is to correctly cover the frequency space of the object. For this inverse problem, we use the classical algorithm of tomographic reconstruction by summation of filtered backprojections. In practice, only a limited number of views are available with our mechanical rig, typically 180, and the frequency bandwidth of the pulses is very limited, typically one octave. The resolving power of the system is them limited by the bandwidth of the pulse. Low and high frequencies can be restored by use of a deconvolution algorithm that enhances resolution. We used a deconvolution technique based on the Papoulis method. The advantage of this technique is conservation of the overall frequency information content of the signals. The enhancement procedure was tested by imaging a square aluminium rod with a cross-section less than the wavelength. In this application, the central frequency of the transducer was 250 kHz so that the central wavelength was 6 mm whereas the cross-section of the rod was 4 mm. Although the Born approximation was not theoretically valid in this case (high contrast), a good reconstruction was obtained.

  11. Automatic abundance analysis of high resolution spectra

    CERN Document Server

    Bonifacio, P; Bonifacio, Piercarlo; Caffau, Elisabetta

    2003-01-01

    We describe an automatic procedure for determining abundances from high resolution spectra. Such procedures are becoming increasingly important as large amounts of data are delivered from 8m telescopes and their high-multiplexing fiber facilities, such as FLAMES on ESO-VLT. The present procedure is specifically targeted for the analysis of spectra of giants in the Sgr dSph; however, the procedure may be, in principle, tailored to analyse stars of any type. Emphasis is placed on the algorithms and on the stability of the method; the external accuracy rests, ultimately, on the reliability of the theoretical models (model-atmospheres, synthetic spectra) used to interpret the data. Comparison of the results of the procedure with the results of a traditional analysis for 12 Sgr giants shows that abundances accurate at the level of 0.2 dex, comparable with that of traditional analysis of the same spectra, may be derived in a fast and efficient way. Such automatic procedures are not meant to replace the traditional ...

  12. Supporting observation campaigns with high resolution modeling

    Science.gov (United States)

    Klocke, Daniel; Brueck, Matthias; Voigt, Aiko

    2017-04-01

    High resolution simulation in support of measurement campaigns offers a promising and emerging way to create large-scale context for small-scale observations of clouds and precipitation processes. As these simulation include the coupling of measured small-scale processes with the circulation, they also help to integrate the research communities from modeling and observations and allow for detailed model evaluations against dedicated observations. In connection with the measurement campaign NARVAL (August 2016 and December 2013) simulations with a grid-spacing of 2.5 km for the tropical Atlantic region (9000x3300 km), with local refinement to 1.2 km for the western part of the domain, were performed using the icosahedral non-hydrostatic (ICON) general circulation model. These simulations are again used to drive large eddy resolving simulations with the same model for selected days in the high definition clouds and precipitation for advancing climate prediction (HD(CP)2) project. The simulations are presented with the focus on selected results showing the benefit for the scientific communities doing atmospheric measurements and numerical modeling of climate and weather. Additionally, an outlook will be given on how similar simulations will support the NAWDEX measurement campaign in the North Atlantic and AC3 measurement campaign in the Arctic.

  13. Resolution enhancement of low quality videos using a high-resolution frame

    NARCIS (Netherlands)

    Pham, T.Q.; Van Vliet, L.J.; Schutte, K.

    2006-01-01

    This paper proposes an example-based Super-Resolution (SR) algorithm of compressed videos in the Discrete Cosine Transform (DCT) domain. Input to the system is a Low-Resolution (LR) compressed video together with a High-Resolution (HR) still image of similar content. Using a training set of correspo

  14. Accelerated high-resolution photoacoustic tomography via compressed sensing

    Science.gov (United States)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  15. High temperature superconducting fault current limiter

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Hinsdale, IL)

    1997-01-01

    A fault current limiter (10) for an electrical circuit (14). The fault current limiter (10) includes a high temperature superconductor (12) in the electrical circuit (14). The high temperature superconductor (12) is cooled below its critical temperature to maintain the superconducting electrical properties during operation as the fault current limiter (10).

  16. Characterization of high-k gate dielectrics by atomic-resolution electron microscopy: current progress and future prospects%高k栅介质原子分辨率的电镜表征:研究进展和展望

    Institute of Scientific and Technical Information of China (English)

    朱信华; 朱健民; 刘治国; 闵乃本

    2009-01-01

    As the downscaling of the feature sizes of complementary metal oxide semiconductor (CMOS) devices enters into the "nuno" era, nanoscale structural characterization at device dimensions becomes critical. A full structural analysis of processed semiconductor devices reqnires an ability to determine atomic positions and local chemical elements and electronic structure. Highresolution (analytical) transmission electron microscopes (HR (A)TEM ), which provide the microscopy techniques such as diffraction contrast imaging (smplimde contrast imaging), high-resolution TEM imaging (phase contrast imaging), selected area electron diffraction and convergent beam electron diffraction, and X-ray energy-dispersive spectroscopy (EDS) and electron energy loss spectroscopy (EELS), have become essential metrology tools in the semiconductor industry. Scanning transmission electron microscope (STEM) with high-angle annular dark field (HAADF) imaging (or Z-contrast incoherent imaging) can directly reveal the structure and chemistry of materials at the atomic scale, due to its imaging intensity being approximately proportional to the square of atomic number (Z) of element. By using Z-contrast imaging and high-resolved EELS spectroscopy, it is very powerful to determine the interfacial structures and the elemental/cbemical environment at/around interfaces within advanced CMOS gate stacks. In recent years the new development of aberration corrector (or, Cs-corrector) makes a revolutionizing the performance of HRTEM/STEM instruments, allowing one to achieve a spatial resolution better than 0.08 nm and an energy resolution better than 0.2 eV, thereby making the characterization of individual nanoscale device structure at sub-atomic scale available. The new generation HRTEM/STEM facility equipped with Cs-corrector will benefit high-k gate materials research in the new era. In this review, some basic principles and key features of atomic-resolution electron microscopy, and the associated high-resolution

  17. A Comparison Study of Tropical Pacific Ocean State Estimation: Low-Resolution Assimilation vs. High-Resolution Simulation

    Institute of Scientific and Technical Information of China (English)

    FU Weiwei; ZHU Jiang; ZHOU Guangqing; WANG Huijun

    2005-01-01

    A comparison study is performed to contrast the improvements in the tropical Pacific oceanic state of a low-resolution model respectively via data assimilation and by an increase in horizontal resolution.A low resolution model (LR) (1°lat by 2°lon) and a high-resolution model (HR) (0.5°lat by 0.5°lon) are employed for the comparison. The authors perform 20-yr numerical experiments and analyze the annual mean fields of temperature and salinity. The results indicate that the low-resolution model with data assimilation behaves better than the high-resolution model in the estimation of ocean large-scale features.From 1990 to 2000, the average of HR's RMSE (root-mean-square error) relative to independent Tropical Atmosphere Ocean project (TAO) mooring data at randomly selected points is 0.97℃ compared to a RMSE of 0.56℃ for LR with temperature assimilation. Moreover, the LR with data assimilation is more frugal in computation. Although there is room to improve the high-resolution model, the low-resolution model with data assimilation may be an advisable choice in achieving a more realistic large-scale state of the ocean at the limited level of information provided by the current observational system.

  18. AIRBORNE HIGH-RESOLUTION DIGITAL IMAGING SYSTEM

    Directory of Open Access Journals (Sweden)

    Prado-Molina, J.

    2006-04-01

    Full Text Available A low-cost airborne digital imaging system capable to perform aerial surveys with small-format cameras isintroduced. The equipment is intended to obtain high-resolution multispectral digital photographs constituting so aviable alternative to conventional aerial photography and satellite imagery. Monitoring software handles all theprocedures involved in image acquisition, including flight planning, real-time graphics for aircraft position updatingin a mobile map, and supervises the main variables engaged in the imaging process. This software also creates fileswith the geographical position of the central point of every image, and the flight path followed by the aircraftduring the entire survey. The cameras are mounted on a three-axis stabilized platform. A set of inertial sensorsdetermines platform's deviations independently from the aircraft and an automatic control system keeps thecameras at a continuous nadir pointing and heading, with a precision better than ± 1 arc-degree in three-axis. Thecontrol system is also in charge of saving the platform’s orientation angles when the monitoring software triggersthe camera. These external orientation parameters, together with a procedure for camera calibration give theessential elements for image orthocorrection. Orthomosaics are constructed using commercial GIS software.This system demonstrates the feasibility of large area coverage in a practical and economical way using smallformatcameras. Monitoring and automatization reduce the work while increasing the quality and the amount ofuseful images.

  19. High spatial resolution probes for neurobiology applications

    Science.gov (United States)

    Gunning, D. E.; Kenney, C. J.; Litke, A. M.; Mathieson, K.

    2009-06-01

    Position-sensitive biological neural networks, such as the brain and the retina, require position-sensitive detection methods to identify, map and study their behavior. Traditionally, planar microelectrodes have been employed to record the cell's electrical activity with device limitations arising from the electrode's 2-D nature. Described here is the development and characterization of an array of electrically conductive micro-needles aimed at addressing the limitations of planar electrodes. The capability of this array to penetrate neural tissue improves the electrode-cell electrical interface and allows more complicated 3-D networks of neurons, such as those found in brain slices, to be studied. State-of-the-art semiconductor fabrication techniques were used to etch and passivate conformally the metal coat and fill high aspect ratio holes in silicon. These are subsequently transformed into needles with conductive tips. This process has enabled the fabrication of arrays of unprecedented dimensions: 61 hexagonally close-packed electrodes, ˜200 μm tall with 60 μm spacing. Electroplating the tungsten tips with platinum ensure suitable impedance values (˜600 kΩ at 1 kHz) for the recording of neuronal signals. Without compromising spatial resolution of the neuronal recordings, this array adds a new and exciting dimension to the study of biological neural networks.

  20. High Spectral Resolution Lidar (HSRL) Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Goldsmith, John [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2016-04-01

    High Spectral Resolution Lidar (HSRL) systems provide vertical profiles of optical depth, backscatter cross-section, depolarization, and backscatter phase function. All HSRL measurements are absolutely calibrated by reference to molecular scattering, which is measured at each point in the lidar profile. Like the Raman lidar but unlike simple backscatter lidars such as the micropulse lidar, the HSRL can measure backscatter cross-sections and optical depths without prior assumptions about the scattering properties of the atmosphere. The depolarization observations also allow robust discrimination between ice and water clouds. In addition, rigorous error estimates can be computed for all measurements. A very narrow, angular field of view reduces multiple scattering contributions. The small field of view, coupled with a narrow optical bandwidth, nearly eliminates noise due to scattered sunlight. There are two operational U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility HSRL systems, one at the Barrow North Slope of Alaska (NSA) site and the other in the second ARM Mobile Facility (AMF2) collection of instrumentation.

  1. Holographic high-resolution endoscopic image recording

    Science.gov (United States)

    Bjelkhagen, Hans I.

    1991-03-01

    Endoscopic holography or endoholography combines the features of endoscopy and holography. The purpose of endoholographic imaging is to provide the physician with a unique means of extending diagnosis by providing a life-like record of tissue. Endoholographic recording will provide means for microscopic examination of tissue and in some cases may obviate the need to excise specimens for biopsy. In this method holograms which have the unique properties of three-dimensionality large focal depth and high resolution are made with a newly designed endoscope. The endoscope uses a single-mode optical fiber for illumination and single-beam reflection holograms are recorded in close contact with the tissue at the distal end of the endoscope. The holograms are viewed under a microscope. By using the proper combinations of dyes for staining specific tissue types with various wavelengths of laser illumination increased contrast on the cellular level can be obtained. Using dyes such as rose bengal in combination with the 514. 5 nm line of an argon ion laser and trypan blue or methylene blue with the 647. 1 nm line of a krypton ion laser holograms of the stained colon of a dog showed the architecture of the colon''s columnar epithelial cells. It is hoped through chronological study using this method in-vivo an increased understanding of the etiology and pathology of diseases such as Crohn''s diseases colitis proctitis and several different forms of cancer will help

  2. High-resolution imaging using endoscopic holography

    Science.gov (United States)

    Bjelkhagen, Hans I.

    1990-08-01

    Endoscopic holography or endoholography combines the features of endoscopy and holography. The purpose of endoholographic imaging is to provide the physician with a unique means of extending diagnosis by providing a life-like record of tissue. Endoholographic recording will provide means for microscopic examination of tissue and in some cases may obviate the need to excise specimens for biopsy. In this method holograms which have the unique properties of three-dimensionality large focal depth and high resolution are made with a newly designed endoscope. The endoscope uses a single-mode optical fiber for illumination and single-beam reflection holograms are recorded in close contact with the tissue at the distal end of the endoscope. The holograms are viewed under a microscope. By using the proper combinations of dyes for staining specific tissue types with various wavelengths of laser illumination increased contrast on the cellular level can be obtained. Using dyes such as rose bengal in combination with the 514. 5 nm line of an argon ion laser and trypan blue or methylene blue with the 647. 1 nm line of a krypton ion laser holograms of the stained colon of a dog showed the architecture of the colon''s columnar epithelial cells. It is hoped through chronological study using this method in-vivo an increased understanding of the etiology and pathology of diseases such as Crohn''s diseases colitis proctitis and several different forms of cancer will help to their control. 1.

  3. Laser wavelength comparison by high resolution interferometry.

    Science.gov (United States)

    Layer, H P; Deslattes, R D; Schweitzer, W G

    1976-03-01

    High resolution interferometry has been used to determine the wavelength ratio between two molecularly stabilized He-Ne lasers, one locked to a methane absorption at 3.39 microm and the other locked to the k peak of (129)I(2) at 633 nm. An optical beat frequency technique gave fractional orders while a microwave sideband method yielded the integer parts. Conventional (third derivative) peak seeking servoes stabilized both laser and cavity lengths. Reproducibility of the electronic control system and optics was a few parts in 10(12), while systematic errors associated with curvature of the cavity mirrors limited the accuracy of the wavelength ratio measurement to 2 parts in 10(10). The measured wavelength ratio of the methane stabilized He-Ne laser at 3.39 microm [P(7) line, nu(3) band] to the (129)I(2) (k peak) stabilized He-Ne laser at 633 nm was 5.359 049 260 6 (0.000 2 ppm). This ratio agrees with that calculated from the (lower accuracy) results of earlier wavelength measurements made relative to the (86)Kr standard. Its higher accuracy thus permits a provisional extension of the frequency scale based on the cesium oscillator into the visible spectrum.

  4. High-resolution tomography of positron emitters with clustered pinhole SPECT

    NARCIS (Netherlands)

    Goorden, M.C.; Beekman, F.J.

    2010-01-01

    State-of-the-art small-animal single photon emission computed tomography (SPECT) enables sub-half-mm resolution imaging of radio-labelled molecules. Due to severe photon penetration through pinhole edges, current multi-pinhole SPECT is not suitable for high-resolution imaging of photons with high

  5. High resolution capacitance detection circuit for rotor micro-gyroscope

    Directory of Open Access Journals (Sweden)

    Ming-Yuan Ren

    2014-03-01

    Full Text Available Conventional methods for rotor position detection of micro-gyroscopes include common exciting electrodes (single frequency and common sensing electrodes (frequency multiplex, but they have encountered some problems. So we present a high resolution and low noise pick-off circuit for micro-gyroscopes which utilizes the time multiplex method. The detecting circuit adopts a continuous-time current sensing circuit for capacitance measurement, and its noise analysis of the charge amplifier is introduced. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. Tests revealed that the whole circuitry has a relative capacitance resolution of 1 × 10−8.

  6. High-resolution ophthalmic imaging system

    Science.gov (United States)

    Olivier, Scot S.; Carrano, Carmen J.

    2007-12-04

    A system for providing an improved resolution retina image comprising an imaging camera for capturing a retina image and a computer system operatively connected to the imaging camera, the computer producing short exposures of the retina image and providing speckle processing of the short exposures to provide the improved resolution retina image. The system comprises the steps of capturing a retina image, producing short exposures of the retina image, and speckle processing the short exposures of the retina image to provide the improved resolution retina image.

  7. Development of a high resolution module for PET scanners

    Science.gov (United States)

    Stringhini, G.; Pizzichemi, M.; Ghezzi, A.; Stojkovic, A.; Tavernier, S.; Niknejad, T.; Varela, J.; Paganoni, M.; Auffray, E.

    2017-02-01

    Positron Emission Tomography (PET) scanners require high performances in term of spatial resolution and sensitivity to allow early detection of cancer masses. In small animal and organ dedicated PET scanners the Depth of Interaction (DOI) information has to be obtained to avoid parallax errors and to reconstruct high resolution images. In the whole body PET, the DOI information can be useful to correct for the time jitter of the optical photons along the main axis of the scintillator, improving the time performances. In this work we present the development of PET module designed to reach high performance as compared to the current scanners while keeping the complexity of the system reasonably low. The module presented is based on a 64 LYSO (Lutetium-yttrium oxyorthosilicate) crystals matrix and on a 4×4 MPPC (Multi Pixels Photon Counter) array as detector in a 4 to 1 coupling between the crystals and the detector and a single side readout. The lateral surfaces of the crystals are optically treated to be unpolished. The DOI and the energy resolution of the PET module are presented and a fast method to obtain the DOI calibration is discussed.

  8. High resolution, MRI-based, segmented, computerized head phantom

    Energy Technology Data Exchange (ETDEWEB)

    Zubal, I.G.; Harrell, C.R.; Smith, E.O.; Smith, A.L.; Krischlunas, P. [Yale Univ., New Haven, CT (United States). Dept. of Diagnostic Radiology

    1999-01-01

    The authors have created a high-resolution software phantom of the human brain which is applicable to voxel-based radiation transport calculations yielding nuclear medicine simulated images and/or internal dose estimates. A software head phantom was created from 124 transverse MRI images of a healthy normal individual. The transverse T2 slices, recorded in a 256x256 matrix from a GE Signa 2 scanner, have isotropic voxel dimensions of 1.5 mm and were manually segmented by the clinical staff. Each voxel of the phantom contains one of 62 index numbers designating anatomical, neurological, and taxonomical structures. The result is stored as a 256x256x128 byte array. Internal volumes compare favorably to those described in the ICRP Reference Man. The computerized array represents a high resolution model of a typical human brain and serves as a voxel-based anthropomorphic head phantom suitable for computer-based modeling and simulation calculations. It offers an improved realism over previous mathematically described software brain phantoms, and creates a reference standard for comparing results of newly emerging voxel-based computations. Such voxel-based computations lead the way to developing diagnostic and dosimetry calculations which can utilize patient-specific diagnostic images. However, such individualized approaches lack fast, automatic segmentation schemes for routine use; therefore, the high resolution, typical head geometry gives the most realistic patient model currently available.

  9. Clickstream data yields high-resolution maps of science

    Energy Technology Data Exchange (ETDEWEB)

    Bollen, Johan [Los Alamos National Laboratory; Van De Sompel, Herbert [Los Alamos National Laboratory; Hagberg, Aric [Los Alamos National Laboratory; Bettencourt, Luis [Los Alamos National Laboratory; Chute, Ryan [Los Alamos National Laboratory; Rodriguez, Marko A [Los Alamos National Laboratory; Balakireva, Lyudmila [Los Alamos National Laboratory

    2009-01-01

    Intricate maps of science have been created from citation data to visualize the structure of scientific activity. However, most scientific publications are now accessed online. Scholarly web portals record detailed log data at a scale that exceeds the number of all existing citations combined. Such log data is recorded immediately upon publication and keeps track of the sequences of user requests (clickstreams) that are issued by a variety of users across many different domains. Given these advantagees of log datasets over citation data, we investigate whether they can produce high-resolution, more current maps of science.

  10. The High Resolution IRAS Galaxy Atlas

    CERN Document Server

    Cao, Y; Prince, T A; Beichman, C A; Cao, Yu; Terebey, Susan; Prince, Thomas A.; Beichman, Charles A.

    1997-01-01

    An atlas of the Galactic plane (-4.7 deg < b < 4.7 deg) plus the molecular clouds in Orion, Rho Oph, and Taurus-Auriga has been produced at 60 and 100 micron from IRAS data. The Atlas consists of resolution-enhanced coadded images having 1 arcmin -- 2 arcmin resolution as well as coadded images at the native IRAS resolution. The IRAS Galaxy Atlas, together with the DRAO HI line / 21 cm continuum and FCRAO CO (1-0) line Galactic plane surveys, both with similar (approx. 1 arcmin) resolution, provide a powerful venue for studying the interstellar medium, star formation and large scale structure in our Galaxy. This paper documents the production and characteristics of the Atlas.

  11. High resolution fire risk mapping in Italy

    Science.gov (United States)

    Fiorucci, Paolo; Biondi, Guido; Campo, Lorenzo; D'Andrea, Mirko

    2014-05-01

    extinguishing actions, leaving more resources to improve safety in areas at risk. With the availability of fire perimeters mapped over a period spanning from 5 to 10 years, depending by the region, a procedure was defined in order to assess areas at risk with high spatial resolution (900 m2) based on objective criteria by observing past fire events. The availability of fire perimeters combined with a detailed knowledge of topography and land cover allowed to understand which are the main features involved in forest fire occurrences and their behaviour. The seasonality of the fire regime was also considered, partitioning the analysis in two macro season (November- April and May- October). In addition, the total precipitation obtained from the interpolation of 30 years-long time series from 460 raingauges and the average air temperature obtained downscaling 30 years ERA-INTERIM data series were considered. About 48000 fire perimeters which burnt about 5500 km2 were considered in the analysis. The analysis has been carried out at 30 m spatial resolution. Some important considerations relating to climate and the territorial features that characterize the fire regime at national level contribute to better understand the forest fire phenomena. These results allow to define new strategies for forest fire prevention and management extensible to other geographical areas.

  12. Super-Resolution Reconstruction of High-Resolution Satellite ZY-3 TLC Images.

    Science.gov (United States)

    Li, Lin; Wang, Wei; Luo, Heng; Ying, Shen

    2017-05-07

    Super-resolution (SR) image reconstruction is a technique used to recover a high-resolution image using the cumulative information provided by several low-resolution images. With the help of SR techniques, satellite remotely sensed images can be combined to achieve a higher-resolution image, which is especially useful for a two- or three-line camera satellite, e.g., the ZY-3 high-resolution Three Line Camera (TLC) satellite. In this paper, we introduce the application of the SR reconstruction method, including motion estimation and the robust super-resolution technique, to ZY-3 TLC images. The results show that SR reconstruction can significantly improve both the resolution and image quality of ZY-3 TLC images.

  13. ESSENSE: Ultra high resolution spectroscopy for the ESS

    Science.gov (United States)

    Pasini, Stefano; Monkenbusch, Michael; Kozielewski, Tadeusz

    2016-09-01

    The instrument concept for a very high intensity neutron spin-echo spectrometer with ultimate resolution properties has been developed and submitted as an instrument proposal to ESS. Effective intensity gain factors up to 30 compared to the best current instruments are anticipated. In addition the resolution will be boosted to the technical limits by newly designed superconducting precession solenoids. The intensity gain results from the use of an optimized guide transporting the high flux from the ESS cold moderator on the one side and from the utilization of an extended wavelength frame of 8 Å yielding a multiplication of information collection rate on the other side. The instrument thus enables novel views on soft matter systems ranging from polymers, functional gels and more to to dynamics of biological molecules with relevance for MD development; the employment of new techniques for surface NSE (GINSE) may contribute to new knowledge in tribology and lubrication and other surface phenomena that currently are hampered by low intensity. New developments in “intelligent” polymers as e.g. self-healing, the properties of which depend on molecular mobility and dynamics, require observation at many 100 ns of correlation times with high intensity, which can be made with ESSENSE.

  14. Large Scale, High Resolution, Mantle Dynamics Modeling

    Science.gov (United States)

    Geenen, T.; Berg, A. V.; Spakman, W.

    2007-12-01

    To model the geodynamic evolution of plate convergence, subduction and collision and to allow for a connection to various types of observational data, geophysical, geodetical and geological, we developed a 4D (space-time) numerical mantle convection code. The model is based on a spherical 3D Eulerian fem model, with quadratic elements, on top of which we constructed a 3D Lagrangian particle in cell(PIC) method. We use the PIC method to transport material properties and to incorporate a viscoelastic rheology. Since capturing small scale processes associated with localization phenomena require a high resolution, we spend a considerable effort on implementing solvers suitable to solve for models with over 100 million degrees of freedom. We implemented Additive Schwartz type ILU based methods in combination with a Krylov solver, GMRES. However we found that for problems with over 500 thousend degrees of freedom the convergence of the solver degraded severely. This observation is known from the literature [Saad, 2003] and results from the local character of the ILU preconditioner resulting in a poor approximation of the inverse of A for large A. The size of A for which ILU is no longer usable depends on the condition of A and on the amount of fill in allowed for the ILU preconditioner. We found that for our problems with over 5×105 degrees of freedom convergence became to slow to solve the system within an acceptable amount of walltime, one minute, even when allowing for considerable amount of fill in. We also implemented MUMPS and found good scaling results for problems up to 107 degrees of freedom for up to 32 CPU¡¯s. For problems with over 100 million degrees of freedom we implemented Algebraic Multigrid type methods (AMG) from the ML library [Sala, 2006]. Since multigrid methods are most effective for single parameter problems, we rebuild our model to use the SIMPLE method in the Stokes solver [Patankar, 1980]. We present scaling results from these solvers for 3D

  15. High Resolution Pulse Compression Imaging Using Super Resolution FM-Chirp Correlation Method (SCM)

    Science.gov (United States)

    Fujiwara, M.; Okubo, K.; Tagawa, N.

    This study addresses the issue of the super-resolution pulse compression technique (PCT) for ultrasound imaging. Time resolution of multiple ultrasonic echoes using the FM-Chirp PCT is limited by the bandwidth of the sweep-frequency. That is, the resolution depends on the sharpness of auto-correlation function. We propose the Super resolution FM-Chirp correlation Method (SCM) and evaluate its performance. This method is based on the multiple signal classification (MUSIC) algorithm. Our simulations were made for the model assuming multiple signals reflected from some scatterers. We confirmed that SCM detects time delay of complicated reflected signals successfully with high resolution.

  16. High-resolution multimodal clinical multiphoton tomography of skin

    Science.gov (United States)

    König, Karsten

    2011-03-01

    This review focuses on multimodal multiphoton tomography based on near infrared femtosecond lasers. Clinical multiphoton tomographs for 3D high-resolution in vivo imaging have been placed into the market several years ago. The second generation of this Prism-Award winning High-Tech skin imaging tool (MPTflex) was introduced in 2010. The same year, the world's first clinical CARS studies have been performed with a hybrid multimodal multiphoton tomograph. In particular, non-fluorescent lipids and water as well as mitochondrial fluorescent NAD(P)H, fluorescent elastin, keratin, and melanin as well as SHG-active collagen has been imaged with submicron resolution in patients suffering from psoriasis. Further multimodal approaches include the combination of multiphoton tomographs with low-resolution wide-field systems such as ultrasound, optoacoustical, OCT, and dermoscopy systems. Multiphoton tomographs are currently employed in Australia, Japan, the US, and in several European countries for early diagnosis of skin cancer, optimization of treatment strategies, and cosmetic research including long-term testing of sunscreen nanoparticles as well as anti-aging products.

  17. Spatial Ensemble Postprocessing of Precipitation Forecasts Using High Resolution Analyses

    Science.gov (United States)

    Lang, Moritz N.; Schicker, Irene; Kann, Alexander; Wang, Yong

    2017-04-01

    Ensemble prediction systems are designed to account for errors or uncertainties in the initial and boundary conditions, imperfect parameterizations, etc. However, due to sampling errors and underestimation of the model errors, these ensemble forecasts tend to be underdispersive, and to lack both reliability and sharpness. To overcome such limitations, statistical postprocessing methods are commonly applied to these forecasts. In this study, a full-distributional spatial post-processing method is applied to short-range precipitation forecasts over Austria using Standardized Anomaly Model Output Statistics (SAMOS). Following Stauffer et al. (2016), observation and forecast fields are transformed into standardized anomalies by subtracting a site-specific climatological mean and dividing by the climatological standard deviation. Due to the need of fitting only a single regression model for the whole domain, the SAMOS framework provides a computationally inexpensive method to create operationally calibrated probabilistic forecasts for any arbitrary location or for all grid points in the domain simultaneously. Taking advantage of the INCA system (Integrated Nowcasting through Comprehensive Analysis), high resolution analyses are used for the computation of the observed climatology and for model training. The INCA system operationally combines station measurements and remote sensing data into real-time objective analysis fields at 1 km-horizontal resolution and 1 h-temporal resolution. The precipitation forecast used in this study is obtained from a limited area model ensemble prediction system also operated by ZAMG. The so called ALADIN-LAEF provides, by applying a multi-physics approach, a 17-member forecast at a horizontal resolution of 10.9 km and a temporal resolution of 1 hour. The performed SAMOS approach statistically combines the in-house developed high resolution analysis and ensemble prediction system. The station-based validation of 6 hour precipitation sums

  18. High Resolution Continuous Flow Analysis System for Polar Ice Cores

    Science.gov (United States)

    Dallmayr, Remi; Azuma, Kumiko; Yamada, Hironobu; Kjær, Helle Astrid; Vallelonga, Paul; Azuma, Nobuhiko; Takata, Morimasa

    2014-05-01

    In the last decades, Continuous Flow Analysis (CFA) technology for ice core analyses has been developed to reconstruct the past changes of the climate system 1), 2). Compared with traditional analyses of discrete samples, a CFA system offers much faster and higher depth resolution analyses. It also generates a decontaminated sample stream without time-consuming sample processing procedure by using the inner area of an ice-core sample.. The CFA system that we have been developing is currently able to continuously measure stable water isotopes 3) and electrolytic conductivity, as well as to collect discrete samples for the both inner and outer areas with variable depth resolutions. Chemistry analyses4) and methane-gas analysis 5) are planned to be added using the continuous water stream system 5). In order to optimize the resolution of the current system with minimal sample volumes necessary for different analyses, our CFA system typically melts an ice core at 1.6 cm/min. Instead of using a wire position encoder with typical 1mm positioning resolution 6), we decided to use a high-accuracy CCD Laser displacement sensor (LKG-G505, Keyence). At the 1.6 cm/min melt rate, the positioning resolution was increased to 0.27mm. Also, the mixing volume that occurs in our open split debubbler is regulated using its weight. The overflow pumping rate is smoothly PID controlled to maintain the weight as low as possible, while keeping a safety buffer of water to avoid air bubbles downstream. To evaluate the system's depth-resolution, we will present the preliminary data of electrolytic conductivity obtained by melting 12 bags of the North Greenland Eemian Ice Drilling (NEEM) ice core. The samples correspond to different climate intervals (Greenland Stadial 21, 22, Greenland Stadial 5, Greenland Interstadial 5, Greenland Interstadial 7, Greenland Stadial 8). We will present results for the Greenland Stadial -8, whose depths and ages are between 1723.7 and 1724.8 meters, and 35.520 to

  19. Hybrid high direct current circuit interrupter

    Science.gov (United States)

    Rockot, J.H.; Mikesell, H.E.; Jha, K.N.

    1998-08-11

    A device and a method are disclosed for interrupting very high direct currents (greater than 100,000 amperes) and simultaneously blocking high voltages (greater than 600 volts). The device utilizes a mechanical switch to carry very high currents continuously with low loss and a silicon controlled rectifier (SCR) to bypass the current around the mechanical switch while its contacts are separating. A commutation circuit, connected in parallel with the SCR, turns off the SCR by utilizing a resonant circuit to divert the SCR current after the switch opens. 7 figs.

  20. High-resolution Quantification of Turbulent Mixing in the North Indian Ocean During the Monsoons

    Science.gov (United States)

    2014-09-30

    High-resolution quantification of turbulent mixing in the North Indian Ocean during the monsoons Sutanu Sarkar Department of Mechanical and...COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE High-resolution Quantification of Turbulent Mixing in the North Indian Ocean During the...corresponding horizontal pressure gradient drives a counter gravity current which causes the bore to decelerate. The counter current also causes the

  1. A superconducting transformer system for high current cable testing.

    Science.gov (United States)

    Godeke, A; Dietderich, D R; Joseph, J M; Lizarazo, J; Prestemon, S O; Miller, G; Weijers, H W

    2010-03-01

    This article describes the development of a direct-current (dc) superconducting transformer system for the high current test of superconducting cables. The transformer consists of a core-free 10,464 turn primary solenoid which is enclosed by a 6.5 turn secondary. The transformer is designed to deliver a 50 kA dc secondary current at a dc primary current of about 50 A. The secondary current is measured inductively using two toroidal-wound Rogowski coils. The Rogowski coil signal is digitally integrated, resulting in a voltage signal that is proportional to the secondary current. This voltage signal is used to control the secondary current using a feedback loop which automatically compensates for resistive losses in the splices to the superconducting cable samples that are connected to the secondary. The system has been commissioned up to 28 kA secondary current. The reproducibility in the secondary current measurement is better than 0.05% for the relevant current range up to 25 kA. The drift in the secondary current, which results from drift in the digital integrator, is estimated to be below 0.5 A/min. The system's performance is further demonstrated through a voltage-current measurement on a superconducting cable sample at 11 T background magnetic field. The superconducting transformer system enables fast, high resolution, economic, and safe tests of the critical current of superconducting cable samples.

  2. High spatial resolution LWIR hyperspectral sensor

    Science.gov (United States)

    Roberts, Carson B.; Bodkin, Andrew; Daly, James T.; Meola, Joseph

    2015-06-01

    Presented is a new hyperspectral imager design based on multiple slit scanning. This represents an innovation in the classic trade-off between speed and resolution. This LWIR design has been able to produce data-cubes at 3 times the rate of conventional single slit scan devices. The instrument has a built-in radiometric and spectral calibrator.

  3. High-speed photography of high-resolution moire patterns

    Science.gov (United States)

    Whitworth, Martin B.; Huntley, Jonathan M.; Field, John E.

    1991-04-01

    The techniques of high resolution moire photography and high speed photography have been combined to allow measurement of the in-plane components of a transient displacement field with microsecond time resolution. Specimen gratings are prepared as casts in a thin layer of epoxy resin on the surface of a specimen. These are illuminated with a flash tube and imaged onto a reference grating with a specially modified camera lens, which incorporates a slotted mask in the aperture plane. For specimen gratings of 75 lines mm1, this selects the +1 and -1 order diffracted beams, thus doubling the effective grating frequency to 150 lines mm1. The resulting real-time moire fringes are recorded with a Hadland 792 image converter camera (Imacon) at an inter-frame time of 2-5ts. The images are digitised and an automatic fringe analysis technique based on the 2-D Fourier transform method is used to extract the displacement information. The technique is illustrated by the results of an investigation into the transient deformation of composite disc specimens, impacted with rectangular metal sliders fired from a gas gun.

  4. Quantum interpolation for high-resolution sensing.

    Science.gov (United States)

    Ajoy, Ashok; Liu, Yi-Xiang; Saha, Kasturi; Marseglia, Luca; Jaskula, Jean-Christophe; Bissbort, Ulf; Cappellaro, Paola

    2017-02-28

    Recent advances in engineering and control of nanoscale quantum sensors have opened new paradigms in precision metrology. Unfortunately, hardware restrictions often limit the sensor performance. In nanoscale magnetic resonance probes, for instance, finite sampling times greatly limit the achievable sensitivity and spectral resolution. Here we introduce a technique for coherent quantum interpolation that can overcome these problems. Using a quantum sensor associated with the nitrogen vacancy center in diamond, we experimentally demonstrate that quantum interpolation can achieve spectroscopy of classical magnetic fields and individual quantum spins with orders of magnitude finer frequency resolution than conventionally possible. Not only is quantum interpolation an enabling technique to extract structural and chemical information from single biomolecules, but it can be directly applied to other quantum systems for superresolution quantum spectroscopy.

  5. High Resolution RPCs for Large TOF Systems

    CERN Document Server

    Ferreira-Marques, R; CERN. Geneva; Carolino, N; Policarpo, Armando; Fonte, P

    1999-01-01

    Here we report on a particular type of RPC that presents above 95% efficiency for minimum ionizing particles and a very sharp time resolution, below 80 ps sigma. Our 9cm2 cells, made with glass and metal electrodes that form accurately spaced gaps of a few hundred micrometers, are operated at atmospheric pressure in non-flammable gases and can be economically produced in large quantities, opening perspectives for the construction of large area timeof flight systems.

  6. Ultra-high resolution electron microscopy

    Science.gov (United States)

    Oxley, Mark P.; Lupini, Andrew R.; Pennycook, Stephen J.

    2017-02-01

    The last two decades have seen dramatic advances in the resolution of the electron microscope brought about by the successful correction of lens aberrations that previously limited resolution for most of its history. We briefly review these advances, the achievement of sub-Ångstrom resolution and the ability to identify individual atoms, their bonding configurations and even their dynamics and diffusion pathways. We then present a review of the basic physics of electron scattering, lens aberrations and their correction, and an approximate imaging theory for thin crystals which provides physical insight into the various different imaging modes. Then we proceed to describe a more exact imaging theory starting from Yoshioka’s formulation and covering full image simulation methods using Bloch waves, the multislice formulation and the frozen phonon/quantum excitation of phonons models. Delocalization of inelastic scattering has become an important limiting factor at atomic resolution. We therefore discuss this issue extensively, showing how the full-width-half-maximum is the appropriate measure for predicting image contrast, but the diameter containing 50% of the excitation is an important measure of the range of the interaction. These two measures can differ by a factor of 5, are not a simple function of binding energy, and full image simulations are required to match to experiment. The Z-dependence of annular dark field images is also discussed extensively, both for single atoms and for crystals, and we show that temporal incoherence must be included accurately if atomic species are to be identified through matching experimental intensities to simulations. Finally we mention a few promising directions for future investigation.

  7. High-quality multi-resolution volume rendering in medicine

    Institute of Scientific and Technical Information of China (English)

    XIE Kai; YANG Jie; LI Xiao-liang

    2007-01-01

    In order to perform a high-quality interactive rendering of large medical data sets on a single off-theshelf PC, a LOD selection algorithm for multi-resolution volume rendering using 3D texture mapping is presented, which uses an adaptive scheme that renders the volume in a region-of-interest at a high resolution and the volume away from this region at lower resolutions. The algorithm is based on several important criteria, and rendering is done adaptively by selecting high-resolution cells close to a center of attention and low-resolution cells away from this area. In addition, our hierarchical level-of-detail representation guarantees consistent interpolation between different resolution levels. Experiments have been applied to a number of large medical data and have produced high quality images at interactive frame rates using standard PC hardware.

  8. High Resolution Energetic X-ray Imager (HREXI)

    Science.gov (United States)

    Grindlay, Jonathan

    We propose to design and build the first imaging hard X-ray detector system that incorporates 3D stacking of closely packed detector readouts in finely-spaced imaging arrays with their required data processing and control electronics. In virtually all imaging astronomical detectors, detector readout is done with flex connectors or connections that are not vertical but rather horizontal , requiring loss of focal plane area. For high resolution pixel detectors needed for high speed event-based X-ray imaging, from low energy applications (CMOS) with focusing X-ray telescopes, to hard X-ray applications with pixelated CZT for large area coded aperture telescopes, this new detector development offers great promise. We propose to extend our previous and current APRA supported ProtoEXIST program that has developed the first large area imaging CZT detectors and demonstrated their astrophysical capabilities on two successful balloon flight to a next generation High Resolution Energetic X-ray Imager (HREXI), which would incorporate microvia technology for the first time to connect the readout ASIC on each CZT crystal directly to its control and data processing system. This 3-dimensional stacking of detector and readout/control system means that large area (>2m2) imaging detector planes for a High Resolution Wide-field hard X-ray telescope can be built with initially greatly reduced detector gaps and ultimately with no gaps. This increases detector area, efficiency, and simplicity of detector integration. Thus higher sensitivity wide-field imagers will be possible at lower cost. HREXI will enable a post-Swift NASA mission such as the EREXS concept proposed to PCOS to be conducted as a future MIDEX mission. This mission would conduct a high resolution (<2 arcmin) , broad band (5 200 keV) hard X-ray survey of black holes on all scales with ~10X higher sensitivity than Swift. In the current era of Time Domain Astrophysics, such a survey capability, in conjunction with a n

  9. Using high-resolution displays for high-resolution cardiac data.

    Science.gov (United States)

    Goodyer, Christopher; Hodrien, John; Wood, Jason; Kohl, Peter; Brodlie, Ken

    2009-07-13

    The ability to perform fast, accurate, high-resolution visualization is fundamental to improving our understanding of anatomical data. As the volumes of data increase from improvements in scanning technology, the methods applied to visualization must evolve. In this paper, we address the interactive display of data from high-resolution magnetic resonance imaging scanning of a rabbit heart and subsequent histological imaging. We describe a visualization environment involving a tiled liquid crystal display panel display wall and associated software, which provides an interactive and intuitive user interface. The oView software is an OpenGL application that is written for the VR Juggler environment. This environment abstracts displays and devices away from the application itself, aiding portability between different systems, from desktop PCs to multi-tiled display walls. Portability between display walls has been demonstrated through its use on walls at the universities of both Leeds and Oxford. We discuss important factors to be considered for interactive two-dimensional display of large three-dimensional datasets, including the use of intuitive input devices and level of detail aspects.

  10. High pressure, high current, low inductance, high reliability sealed terminals

    Science.gov (United States)

    Hsu, John S [Oak Ridge, TN; McKeever, John W [Oak Ridge, TN

    2010-03-23

    The invention is a terminal assembly having a casing with at least one delivery tapered-cone conductor and at least one return tapered-cone conductor routed there-through. The delivery and return tapered-cone conductors are electrically isolated from each other and positioned in the annuluses of ordered concentric cones at an off-normal angle. The tapered cone conductor service can be AC phase conductors and DC link conductors. The center core has at least one service conduit of gate signal leads, diagnostic signal wires, and refrigerant tubing routed there-through. A seal material is in direct contact with the casing inner surface, the tapered-cone conductors, and the service conduits thereby hermetically filling the interstitial space in the casing interior core and center core. The assembly provides simultaneous high-current, high-pressure, low-inductance, and high-reliability service.

  11. High resolution FESEM and TEM reveal bacterial spore attachment.

    Science.gov (United States)

    Panessa-Warren, Barbara J; Tortora, George T; Warren, John B

    2007-08-01

    Transmission electron microscopy (TEM) studies in the 1960s and early 1970s using conventional thin section and freeze fracture methodologies revealed ultrastructural bacterial spore appendages. However, the limited technology at that time necessitated the time-consuming process of imaging serial sections and reconstructing each structure. Consequently, the distribution and function of these appendages and their possible role in colonization or pathogenesis remained unknown. By combining high resolution field emission electron microscopy with TEM images of identical bacterial spore preparations, we have been able to obtain images of intact and sectioned Bacillus and Clostridial spores to clearly visualize the appearance, distribution, resistance (to trypsin, chloramphenicol, and heat), and participation of these structures to facilitate attachment of the spores to glass, agar, and human cell substrates. Current user-friendly commercial field emission scanning electron microscopes (FESEMs), permit high resolution imaging, with high brightness guns at lower accelerating voltages for beam sensitive intact biological samples, providing surface images at TEM magnifications for making direct comparisons. For the first time, attachment structures used by pathogenic, environmental, and thermophile bacterial spores could be readily visualized on intact spores to reveal how specific appendages and outer spore coats participated in spore attachment, colonization, and invasion.

  12. A System for High-Resolution Topology Optimization.

    Science.gov (United States)

    Wu, Jun; Dick, Christian; Westermann, Rudiger

    2016-03-01

    A key requirement in 3D fabrication is to generate objects with individual exterior shapes and their interior being optimized to application-specific force constraints and low material consumption. Accomplishing this task is challenging on desktop computers, due to the extreme model resolutions that are required to accurately predict the physical shape properties, requiring memory and computational capacities going beyond what is currently available. Moreover, fabrication-specific constraints need to be considered to enable printability. To address these challenges, we present a scalable system for generating 3D objects using topology optimization, which allows to efficiently evolve the topology of high-resolution solids towards printable and light-weight-high-resistance structures. To achieve this, the system is equipped with a high-performance GPU solver which can efficiently handle models comprising several millions of elements. A minimum thickness constraint is built into the optimization process to automatically enforce printability of the resulting shapes. We further shed light on the question how to incorporate geometric shape constraints, such as symmetry and pattern repetition, in the optimization process. We analyze the performance of the system and demonstrate its potential by a variety of different shapes such as interior structures within closed surfaces, exposed support structures, and surface models.

  13. High-resolution 3-T MR neurography of peroneal neuropathy

    Energy Technology Data Exchange (ETDEWEB)

    Chhabra, Avneesh; Faridian-Aragh, Neda; Chalian, Majid; Soldatos, Theodoros; Thawait, Shrey K. [Johns Hopkins Hospital, The Russell H. Morgan Department of Radiology and Radiological Science, Baltimore, MD (United States); Williams, Eric H. [Johns Hopkins Hospital, Department of Plastic Surgery, Baltimore, MD (United States); Dellon Institute for Peripheral Nerve Surgery, Baltimore, MD (United States); Andreisek, Gustav [University Hospital Zurich, Institute for Diagnostic Radiology, Department of Medical Radiology, Zurich (Switzerland)

    2012-03-15

    The common peroneal nerve (CPN), a major terminal branch of the sciatic nerve, can be subject to a variety of pathologies, which may affect the nerve at any level from the lumbar plexus to its distal branches. Although the diagnosis of peripheral neuropathy is traditionally based on a patient's clinical findings and electrodiagnostic tests, magnetic resonance neurography (MRN) is gaining an increasing role in the definition of the type, site, and extent of peripheral nerve disorders. Current high-field MR scanners enable high-resolution and excellent soft-tissue contrast imaging of peripheral nerves. In the lower extremities, MR neurography has been employed in the demonstration of the anatomy and pathology of the CPN, as well as in the detection of associated secondary muscle denervation changes. This article reviews the normal appearance of the CPN as well as typical pathologies and abnormal findings at 3.0-T MR neurography of the lower extremity. (orig.)

  14. High resolution mosaic image of capillaries in human retina by adaptive optics

    Institute of Scientific and Technical Information of China (English)

    Ning Ling; Yudong Zhang; Xuejun Rao; Cheng Wang; Yiyun Hu; Wenhan Jiang

    2005-01-01

    Adaptive optics (AO) has been proved as a powerful means for high resolution imaging of human retina.Because of the pixel number of charge-coupled device (CCD) camera, the field of view is limited to 1°.In order to have image of capillaries around vivo human fovea, we use mosaic method to obtain high resolution image in area of 6°× 6°. Detailed structures of capillaries around fovea with resolution of 2.3μm are clearly shown. Comparison shows that this method has a much higher resolution than current clinic retina imaging methods.

  15. Proceedings of the workshop on high resolution computed microtomography (CMT)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    The purpose of the workshop was to determine the status of the field, to define instrumental and computational requirements, and to establish minimum specifications required by possible users. The most important message sent by implementers was the remainder that CMT is a tool. It solves a wide spectrum of scientific problems and is complementary to other microscopy techniques, with certain important advantages that the other methods do not have. High-resolution CMT can be used non-invasively and non-destructively to study a variety of hierarchical three-dimensional microstructures, which in turn control body function. X-ray computed microtomography can also be used at the frontiers of physics, in the study of granular systems, for example. With high-resolution CMT, for example, three-dimensional pore geometries and topologies of soils and rocks can be obtained readily and implemented directly in transport models. In turn, these geometries can be used to calculate fundamental physical properties, such as permeability and electrical conductivity, from first principles. Clearly, use of the high-resolution CMT technique will contribute tremendously to the advancement of current R and D technologies in the production, transport, storage, and utilization of oil and natural gas. It can also be applied to problems related to environmental pollution, particularly to spilling and seepage of hazardous chemicals into the Earth's subsurface. Applications to energy and environmental problems will be far-ranging and may soon extend to disciplines such as materials science--where the method can be used in the manufacture of porous ceramics, filament-resin composites, and microelectronics components--and to biomedicine, where it could be used to design biocompatible materials such as artificial bones, contact lenses, or medication-releasing implants. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  16. High dislocation density of tin induced by electric current

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Yi-Han; Liang, Chien-Lung; Lin, Kwang-Lung, E-mail: matkllin@mail.ncku.edu.tw [Department of Material Science and Engineering, National Cheng Kung University, Tainan 70101, Taiwan, R. O. C (China); Wu, Albert T. [Department of Chemical and Material Engineering, National Central University, Jhongli 32001, Taiwan, R. O. C (China)

    2015-12-15

    A dislocation density of as high as 10{sup 17} /m{sup 2} in a tin strip, as revealed by high resolution transmission electron microscope, was induced by current stressing at 6.5 x 10{sup 3} A/ cm{sup 2}. The dislocations exist in terms of dislocation line, dislocation loop, and dislocation aggregates. Electron Backscattered Diffraction images reflect that the high dislocation density induced the formation of low deflection angle subgrains, high deflection angle Widmanstätten grains, and recrystallization. The recrystallization gave rise to grain refining.

  17. High resolution RPC's for large TOF systems

    CERN Document Server

    Fonte, Paulo J R; Pinhão, J; Carolino, N; Policarpo, Armando

    2000-01-01

    Here we report on a particular type of RPC that presents up to 99% efficiency for minimum ionizing particles and a very good time resolution, below 50 ps s for the most optimized construction. Our 9 cm2 cells, made with glass and metal electrodes that form accurately spaced gaps of a few hundred micrometers, are operated at atmospheric pressure in non-flammable gases and can be economically produced in large quantities, opening perspectives for the construction of large area time of flight systems.

  18. High resolution IVEM tomography of biological specimens

    Energy Technology Data Exchange (ETDEWEB)

    Sedat, J.W.; Agard, D.A. [Univ. of California, San Francisco, CA (United States)

    1997-02-01

    Electron tomography is a powerful tool for elucidating the three-dimensional architecture of large biological complexes and subcellular organelles. The introduction of intermediate voltage electron microscopes further extended the technique by providing the means to examine very large and non-symmetrical subcellular organelles, at resolutions beyond what would be possible using light microscopy. Recent studies using electron tomography on a variety of cellular organelles and assemblies such as centrosomes, kinetochores, and chromatin have clearly demonstrated the power of this technique for obtaining 3D structural information on non-symmetric cell components. When combined with biochemical and molecular observations, these 3D reconstructions have provided significant new insights into biological function.

  19. DSCOVR High Time Resolution Solar Wind Measurements

    Science.gov (United States)

    Szabo, Adam

    2012-01-01

    The Deep Space Climate Observatory (DSCOVR), previously known as Triana, spacecraft is expected to be launched in late 2014. It will carry a fluxgate magnetometer, Faraday Cup solar wind detector and a top-hat electron electrostatic analyzer. The Faraday Cup will provide an unprecedented 10 vectors/sec time resolution measurement of the solar wind proton and alpha reduced distribution functions. Coupled with the 40 vector/sec vector magnetometer measurements, the identification of specific wave modes in the solar wind will be possible for the first time. The science objectives and data products of the mission will be discussed.

  20. Nanosecond microscopy with a high spectroscopic resolution

    CERN Document Server

    Heinrich, C; Ritsch-Marte, M; Bernet, Stefan; Heinrich, Christoph; Ritsch-Marte, Monika

    2005-01-01

    We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy in a wide-field setup with nanosecond laser pulse excitation. In contrast to confocal setups, the image of a sample can be recorded with a single pair of excitation pulses. For this purpose the excitation geometry is specially designed in order to satisfy the phase matching condition over the whole sample area. The spectral, temporal and spatial sensitivity of the method is demonstrated by imaging test samples, i.e. oil vesicles in sunflower seeds, on a nanosecond timescale. The method provides snapshot imaging in 3 nanoseconds with a spectral resolution of 25 wavenumbers (cm$^{-1}$).

  1. Achieving sensitive, high-resolution laser spectroscopy at CRIS

    Energy Technology Data Exchange (ETDEWEB)

    Groote, R. P. de [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Lynch, K. M., E-mail: kara.marie.lynch@cern.ch [EP Department, CERN, ISOLDE (Switzerland); Wilkins, S. G. [The University of Manchester, School of Physics and Astronomy (United Kingdom); Collaboration: the CRIS collaboration

    2017-11-15

    The Collinear Resonance Ionization Spectroscopy (CRIS) experiment, located at the ISOLDE facility, has recently performed high-resolution laser spectroscopy, with linewidths down to 20 MHz. In this article, we present the modifications to the beam line and the newly-installed laser systems that have made sensitive, high-resolution measurements possible. Highlights of recent experimental campaigns are presented.

  2. Towards high resolution data assimilation and ensemble forecasting

    NARCIS (Netherlands)

    Stappers, R.J.J.

    2013-01-01

    Due the increase in computational power of supercomputers the grid resolution of high resolution numerical weather prediction models is now reaching the 1 km scale. As a result, mesoscale processes related to high impact weather (such as deep convection) can now explicitly be resolved by the models.

  3. High-resolution X-ray diffraction studies of multilayers

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Hornstrup, Allan; Schnopper, H. W.

    1988-01-01

    High-resolution X-ray diffraction studies of the perfection of state-of-the-art multilayers are presented. Data were obtained using a triple-axis perfect-crystal X-ray diffractometer. Measurements reveal large-scale figure errors in the substrate. A high-resolution triple-axis set up is required...

  4. High Resolution X-Ray Spectroscopy with a Microcalorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Norrell, J.; Anderson, I.

    2005-01-01

    Energy-dispersive spectrometry (EDS) is often the preferred choice for X-ray microanalysis, but there are still many disadvantages associated with EDS, the most significant of which is the relatively poor energy resolution, which limits detection sensitivity and the ability to distinguish among closely spaced spectral features, limiting even qualitative analysis. A new type of EDS detector that operates on the principle of microcalorimetry has the potential to eliminate this shortcoming, reaching resolutions an order of magnitude better. The detector consists of an absorber in thermal contact with a transition edge sensor (TES). An X-ray from the specimen hits the absorber and manifests itself as a change in temperature. Because the system is kept at 80 mK, the heat capacity is low and the temperature spike is observable. The TES responds to the increase in temperature by transitioning from its superconducting to its normal conducting state, thus sharply raising the overall resistance of the circuit. The circuit is kept at a constant voltage, so the increase in resistance is manifested as a decrease in current flow. This decrease in current is measured by a superconducting quantum interference device (SQUID), and by integrating the current over time, the energy of the incident X-ray is determined. The prototype microcalorimeter was developed by NIST, and this technology is now available commercially through a partnership between Vericold Technologies and EDAX International. ORNL has received the first of these commercial microcalorimeters in the United States. The absorber in this detector is gold, and the TES consists of a gold-iridium bilayer. It is designed to offer spectral resolution of 10-15 eV at a count rate of ~150 s-1. The goal of this project was to analyze and document the performance of the detector, with particular attention given to the effects of an X-ray optic used to improve collection efficiency, the multiple window system and any other sources

  5. High-Speed Smart Camera with High Resolution

    Directory of Open Access Journals (Sweden)

    J. Dubois

    2007-02-01

    Full Text Available High-speed video cameras are powerful tools for investigating for instance the biomechanics analysis or the movements of mechanical parts in manufacturing processes. In the past years, the use of CMOS sensors instead of CCDs has enabled the development of high-speed video cameras offering digital outputs, readout flexibility, and lower manufacturing costs. In this paper, we propose a high-speed smart camera based on a CMOS sensor with embedded processing. Two types of algorithms have been implemented. A compression algorithm, specific to high-speed imaging constraints, has been implemented. This implementation allows to reduce the large data flow (6.55 Gbps and to propose a transfer on a serial output link (USB 2.0. The second type of algorithm is dedicated to feature extraction such as edge detection, markers extraction, or image analysis, wavelet analysis, and object tracking. These image processing algorithms have been implemented into an FPGA embedded inside the camera. These implementations are low-cost in terms of hardware resources. This FPGA technology allows us to process in real time 500 images per second with a 1280×1024 resolution. This camera system is a reconfigurable platform, other image processing algorithms can be implemented.

  6. High-Speed Smart Camera with High Resolution

    Directory of Open Access Journals (Sweden)

    Mosqueron R

    2007-01-01

    Full Text Available High-speed video cameras are powerful tools for investigating for instance the biomechanics analysis or the movements of mechanical parts in manufacturing processes. In the past years, the use of CMOS sensors instead of CCDs has enabled the development of high-speed video cameras offering digital outputs, readout flexibility, and lower manufacturing costs. In this paper, we propose a high-speed smart camera based on a CMOS sensor with embedded processing. Two types of algorithms have been implemented. A compression algorithm, specific to high-speed imaging constraints, has been implemented. This implementation allows to reduce the large data flow (6.55 Gbps and to propose a transfer on a serial output link (USB 2.0. The second type of algorithm is dedicated to feature extraction such as edge detection, markers extraction, or image analysis, wavelet analysis, and object tracking. These image processing algorithms have been implemented into an FPGA embedded inside the camera. These implementations are low-cost in terms of hardware resources. This FPGA technology allows us to process in real time 500 images per second with a 1280×1024 resolution. This camera system is a reconfigurable platform, other image processing algorithms can be implemented.

  7. High-Resolution Sonars: What Resolution Do We Need for Target Recognition?

    Directory of Open Access Journals (Sweden)

    Pailhas Yan

    2010-01-01

    Full Text Available Target recognition in sonar imagery has long been an active research area in the maritime domain, especially in the mine-counter measure context. Recently it has received even more attention as new sensors with increased resolution have been developed; new threats to critical maritime assets and a new paradigm for target recognition based on autonomous platforms have emerged. With the recent introduction of Synthetic Aperture Sonar systems and high-frequency sonars, sonar resolution has dramatically increased and noise levels decreased. Sonar images are distance images but at high resolution they tend to appear visually as optical images. Traditionally algorithms have been developed specifically for imaging sonars because of their limited resolution and high noise levels. With high-resolution sonars, algorithms developed in the image processing field for natural images become applicable. However, the lack of large datasets has hampered the development of such algorithms. Here we present a fast and realistic sonar simulator enabling development and evaluation of such algorithms.We develop a classifier and then analyse its performances using our simulated synthetic sonar images. Finally, we discuss sensor resolution requirements to achieve effective classification of various targets and demonstrate that with high resolution sonars target highlight analysis is the key for target recognition.

  8. High-resolution gravity field modeling using GRAIL mission data

    Science.gov (United States)

    Lemoine, F. G.; Goossens, S. J.; Sabaka, T. J.; Nicholas, J. B.; Mazarico, E.; Rowlands, D. D.; Neumann, G. A.; Loomis, B.; Chinn, D. S.; Smith, D. E.; Zuber, M. T.

    2015-12-01

    The Gravity Recovery and Interior Laboratory (GRAIL) spacecraft were designed to map the structure of the Moon through high-precision global gravity mapping. The mission consisted of two spacecraft with Ka-band inter-satellite tracking complemented by tracking from Earth. The mission had two phases: a primary mapping mission from March 1 until May 29, 2012 at an average altitude of 50 km, and an extended mission from August 30 until December 14, 2012, with an average altitude of 23 km before November 18, and 20 and 11 km after. High-resolution gravity field models using both these data sets have been estimated, with the current resolution being degree and order 1080 in spherical harmonics. Here, we focus on aspects of the analysis of the GRAIL data: we investigate eclipse modeling, the influence of empirical accelerations on the results, and we discuss the inversion of large-scale systems. In addition to global models we also estimated local gravity adjustments in areas of particular interest such as Mare Orientale, the south pole area, and the farside. We investigate the use of Ka-band Range Rate (KBRR) data versus numerical derivatives of KBRR data, and show that the latter have the capability to locally improve correlations with topography.

  9. Special issue on high-resolution optical imaging

    Science.gov (United States)

    Smith, Peter J. S.; Davis, Ilan; Galbraith, Catherine G.; Stemmer, Andreas

    2013-09-01

    The pace of development in the field of advanced microscopy is truly breath-taking, and is leading to major breakthroughs in our understanding of molecular machines and cell function. This special issue of Journal of Optics draws attention to a number of interesting approaches, ranging from fluorescence and imaging of unlabelled cells, to computational methods, all of which are describing the ever increasing detail of the dynamic behaviour of molecules in the living cell. This is a field which traditionally, and currently, demonstrates a marvellous interplay between the disciplines of physics, chemistry and biology, where apparent boundaries to resolution dissolve and living cells are viewed in ever more clarity. It is fertile ground for those interested in optics and non-conventional imaging to contribute high-impact outputs in the fields of cell biology and biomedicine. The series of articles presented here has been selected to demonstrate this interdisciplinarity and to encourage all those with a background in the physical sciences to 'dip their toes' into the exciting and dynamic discoveries surrounding cell function. Although single molecule super-resolution microscopy is commercially available, specimen preparation and interpretation of single molecule data remain a major challenge for scientists wanting to adopt the techniques. The paper by Allen and Davidson [1] provides a much needed detailed introduction to the practical aspects of stochastic optical reconstruction microscopy, including sample preparation, image acquisition and image analysis, as well as a brief description of the different variants of single molecule localization microscopy. Since super-resolution microscopy is no longer restricted to three-dimensional imaging of fixed samples, the review by Fiolka [2] is a timely introduction to techniques that have been successfully applied to four-dimensional live cell super-resolution microscopy. The combination of multiple high-resolution techniques

  10. The high spectral resolution (scanning) lidar (HSRL)

    Energy Technology Data Exchange (ETDEWEB)

    Eloranta, E. [Univ. of Wisconsin, Madison, WI (United States)

    1995-09-01

    Lidars enable the spatial resolution of optical depth variation in clouds. The optical depth must be inverted from the backscatter signal, a process which is complicated by the fact that both molecular and aerosol backscatter signals are present. The HSRL has the advantage of allowing these two signals to be separated. It has a huge dynamic range, allowing optical depth retrieval for t = 0.01 to 3. Depolarization is used to determine the nature of hydrometeors present. Experiments show that water clouds must almost always be taken into account during cirrus observations. An exciting new development is the possibility of measuring effective radius via diffraction peak width and variable field-of-view measurements. 2 figs.

  11. Studying stellar populations at high spectral resolution

    CERN Document Server

    Bruzual, Gustavo A

    2007-01-01

    I describe very briefly the new libraries of empirical spectra of stars covering wide ranges of values of the atmospheric parameters Teff, log g, [Fe/H], as well as spectral type, that have become available in the recent past, among them the HNGSL, MILES, UVES-POP, ELODIE, and the IndoUS libraries. I show the results of using the IndoUS and the HNGSL libraries, as well as an atlas of theoretical model atmospheres, to build population synthesis models. These libraries are complementary in spectral resolution and wavelength coverage, and will prove extremely useful to describe spectral features expected in galaxy spectra from the NUV to the NIR. The fits to observed galaxy spectra using simple and composite stellar population models are discussed.

  12. High resolution 3D imaging of synchrotron generated microbeams

    Energy Technology Data Exchange (ETDEWEB)

    Gagliardi, Frank M., E-mail: frank.gagliardi@wbrc.org.au [Alfred Health Radiation Oncology, The Alfred, Melbourne, Victoria 3004, Australia and School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia); Cornelius, Iwan [Imaging and Medical Beamline, Australian Synchrotron, Clayton, Victoria 3168, Australia and Centre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales 2500 (Australia); Blencowe, Anton [Division of Health Sciences, School of Pharmacy and Medical Sciences, The University of South Australia, Adelaide, South Australia 5000, Australia and Division of Information Technology, Engineering and the Environment, Mawson Institute, University of South Australia, Mawson Lakes, South Australia 5095 (Australia); Franich, Rick D. [School of Applied Sciences and Health Innovations Research Institute, RMIT University, Melbourne, Victoria 3000 (Australia); Geso, Moshi [School of Medical Sciences, RMIT University, Bundoora, Victoria 3083 (Australia)

    2015-12-15

    Purpose: Microbeam radiation therapy (MRT) techniques are under investigation at synchrotrons worldwide. Favourable outcomes from animal and cell culture studies have proven the efficacy of MRT. The aim of MRT researchers currently is to progress to human clinical trials in the near future. The purpose of this study was to demonstrate the high resolution and 3D imaging of synchrotron generated microbeams in PRESAGE® dosimeters using laser fluorescence confocal microscopy. Methods: Water equivalent PRESAGE® dosimeters were fabricated and irradiated with microbeams on the Imaging and Medical Beamline at the Australian Synchrotron. Microbeam arrays comprised of microbeams 25–50 μm wide with 200 or 400 μm peak-to-peak spacing were delivered as single, cross-fire, multidirectional, and interspersed arrays. Imaging of the dosimeters was performed using a NIKON A1 laser fluorescence confocal microscope. Results: The spatial fractionation of the MRT beams was clearly visible in 2D and up to 9 mm in depth. Individual microbeams were easily resolved with the full width at half maximum of microbeams measured on images with resolutions of as low as 0.09 μm/pixel. Profiles obtained demonstrated the change of the peak-to-valley dose ratio for interspersed MRT microbeam arrays and subtle variations in the sample positioning by the sample stage goniometer were measured. Conclusions: Laser fluorescence confocal microscopy of MRT irradiated PRESAGE® dosimeters has been validated in this study as a high resolution imaging tool for the independent spatial and geometrical verification of MRT beam delivery.

  13. Application of grid-nesting technique on sandwaves migration simulation Ⅰ——Ultra-high resolution 3D current simulation%网格嵌套技术在模拟海底沙波运移中的应用Ⅰ——超高分辨率海洋三维流场模拟

    Institute of Scientific and Technical Information of China (English)

    江文滨; 林缅

    2011-01-01

    本文采用POM(Princeton Ocean Model)模式,结合多波束测量得到的高分辨率地形数据,通过网格嵌套分级计算,得到了南海北部琼西南海域近40km2研究区内的水平网格分辨率达200 m的海底流场.通过数值试验,确定了内嵌模型的最佳侧面开边界条件.计算结果表明,本文所提出超高水平分辨率嵌套模式能够模拟复杂海洋地形上的余流特征.研究证明,本文为模拟开边界小区域海洋三维流场提供了一种较为快速、准确的方法.该方法的水平分辨率是目前国际上流行的高分辨率的9倍,也可用于开边界小区域物理海洋环境的数值模拟.%Adopting the Princeton Ocean Model, a model with horizontal resolution of about 200 m is developed in this paper to simulate the bottom current field of the small study area in the north of South China Sea. The grid-nesting technique is used twice in this model with the high-resolution bathymetry data measured by multi-beam equipments. The lateral open boundary conditions of the nested model are selected by numerical experiments. It is proved that this ultra-high resolution model is able to simulate the residual current of the area with complex ocean topography and is a quick and accurate way to get three-dimensional high-resolution ocean current field of small sea area with open boundaries. The resolution is nine times as high as international advanced level. The model developed here is also applicable for researches on small scale ocean environment.

  14. Research Relative to High Spatial Resolution Passive Microwave Sounding Systems

    Science.gov (United States)

    Staelin, D. H.; Rosenkranz, P. W.

    1984-01-01

    Methods to obtain high resolution passive microwave weather observations, and understanding of their probable impact on numerical weather prediction accuracy were investigated. The development of synthetic aperture concepts for geosynchronous passive microwave sounders were studied. The effects of clouds, precipitation, surface phenomena, and atmospheric thermal fine structure on a scale of several kilometers were examined. High resolution passive microwave sounders (e.g., AMSU) with an increased number of channels will produce initialization data for numerical weather prediction (NWP) models with both increased spatial resolution and coverage. The development of statistical models for error growth in high resolution primitive equation NWP models which permit the consequences of various observing system alternatives, including sensors and assimilation times and procedures is discussed. A high resolution three dimensional primitive equation NWP model to determine parameters in an error growth model similar to that formulated by Lorenz, but with more degrees of freedom is utilized.

  15. Whole-animal imaging with high spatio-temporal resolution

    Science.gov (United States)

    Chhetri, Raghav; Amat, Fernando; Wan, Yinan; Höckendorf, Burkhard; Lemon, William C.; Keller, Philipp J.

    2016-03-01

    We developed isotropic multiview (IsoView) light-sheet microscopy in order to image fast cellular dynamics, such as cell movements in an entire developing embryo or neuronal activity throughput an entire brain or nervous system, with high resolution in all dimensions, high imaging speeds, good physical coverage and low photo-damage. To achieve high temporal resolution and high spatial resolution at the same time, IsoView microscopy rapidly images large specimens via simultaneous light-sheet illumination and fluorescence detection along four orthogonal directions. In a post-processing step, these four views are then combined by means of high-throughput multiview deconvolution to yield images with a system resolution of ≤ 450 nm in all three dimensions. Using IsoView microscopy, we performed whole-animal functional imaging of Drosophila embryos and larvae at a spatial resolution of 1.1-2.5 μm and at a temporal resolution of 2 Hz for up to 9 hours. We also performed whole-brain functional imaging in larval zebrafish and multicolor imaging of fast cellular dynamics across entire, gastrulating Drosophila embryos with isotropic, sub-cellular resolution. Compared with conventional (spatially anisotropic) light-sheet microscopy, IsoView microscopy improves spatial resolution at least sevenfold and decreases resolution anisotropy at least threefold. Compared with existing high-resolution light-sheet techniques, such as lattice lightsheet microscopy or diSPIM, IsoView microscopy effectively doubles the penetration depth and provides subsecond temporal resolution for specimens 400-fold larger than could previously be imaged.

  16. High resolution resonant recombination measurements using evaporative cooling technique

    Energy Technology Data Exchange (ETDEWEB)

    Beilmann, C; Lopez-Urrutia, J R Crespo; Mokler, P H; Ullrich, J, E-mail: christian.beilmann@mpi-hd.mpg.d [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany)

    2010-09-15

    We report on a method significantly improving the energy resolution of dielectronic recombination (DR) measurements in electron beam ion traps (EBITs). The line width of DR resonances can be reduced to values distinctly smaller than the corresponding space charge width of the uncompensated electron beam. The experimental technique based on forced evaporative cooling is presented together with test measurements demonstrating its high efficiency. The principle for resolution improvement is elucidated and the limiting factors are discussed. This method opens access to high resolution DR measurements at high ion-electron collision energies required for innermost shell DR in highly charged ions (HCI).

  17. High-resolution MR imaging of the normal rotator cuff.

    Science.gov (United States)

    Middleton, W D; Kneeland, J B; Carrera, G F; Cates, J D; Kellman, G M; Campagna, N G; Jesmanowicz, A; Froncisz, W; Hyde, J S

    1987-03-01

    The shoulders of six normal volunteers were imaged with high-resolution MR in the axial, sagittal, and coronal planes. An angled pair of counter-rotating current loop-gap resonators designed specifically for the shoulder was used as a local coil. All images were compared with corresponding cryomicrotome sections from cadaver shoulders. The rotator cuff was analyzed in detail. It appeared as a complex, heterogeneous band to tissue superficial to the humeral head. The areas of low signal intensity corresponded to the central tendons of the four rotator cuff muscles. These tendons could be distinguished from each other as well as from the intervening components of the cuff, which have a moderate intensity. We concluded that MR is capable of imaging the normal rotator cuff and of separating the various components. This may allow for improved precision in the diagnosis of rotator cuff disorders.

  18. High Resolution Ionospheric Mapping Using Spaceborne Synthetic Aperture Radars

    Science.gov (United States)

    Meyer, F. J.; Chotoo, K.; Roth, A. P.

    2012-12-01

    Spaceborne Synthetic Aperture Radars (SARs) are imaging radar systems that utilize the Doppler history of signals acquired during satellite flyby to produce high resolution images of the Earth. With modern sensors, operating at frequencies between about 1 GHz (L-band) and 10 GHz (X-band), radar images with resolutions in the meter to sub-meter range can be produced. The presence of the ionosphere is significantly affecting the propagation properties of the microwave signals transmitted by these systems, causing distortions of signal polarization and phase. These distortions can lead to a wide range of imaging artifacts including image range shifts, interferometric phase biases, loss of image focus, change of image geometry, and Faraday rotation. While these artifacts are particularly pronounced at L-band, they are still observable in data acquired at C- or even X-band. In recent years, a wealth of methods for measuring and correcting ionospheric influence were developed. These methods are self-calibration procedures that measure ionosphere-induced distortions to infer the two-dimensional TEC maps that affected the data. These TEC maps are then removed from the data to produce high performance SAR images. Besides being effective in correcting SAR observations, these self-calibration methods are producing high quality TEC information with sub-TECU sensitivity and sub-kilometer spatial resolution. The intent of this paper is to utilize SAR-derived ionospheric information and make the case for SAR as a data source for ionospheric research. After a short summary of ionosphere-induced distortions, the concept of TEC estimation from SAR is introduced. Here, the current state-of-the-art of ionospheric TEC estimation is presented, including Faraday rotation-based, interferometric, correlation-based, and autofocus-based techniques. For every approach, performance numbers are given that quantify the achievable TEC estimation accuracy as a function of system parameters, scene

  19. Semantic-based high resolution remote sensing image retrieval

    Science.gov (United States)

    Guo, Dihua

    High Resolution Remote Sensing (HRRS) imagery has been experiencing extraordinary development in the past decade. Technology development means increased resolution imagery is available at lower cost, making it a precious resource for planners, environmental scientists, as well as others who can learn from the ground truth. Image retrieval plays an important role in managing and accessing huge image database. Current image retrieval techniques, cannot satisfy users' requests on retrieving remote sensing images based on semantics. In this dissertation, we make two fundamental contributions to the area of content based image retrieval. First, we propose a novel unsupervised texture-based segmentation approach suitable for accurately segmenting HRRS images. The results of existing segmentation algorithms dramatically deteriorate if simply adopted to HRRS images. This is primarily clue to the multi-texture scales and the high level noise present in these images. Therefore, we propose an effective and efficient segmentation model, which is a two-step process. At high-level, we improved the unsupervised segmentation algorithm by coping with two special features possessed by HRRS images. By preprocessing images with wavelet transform, we not only obtain multi-resolution images but also denoise the original images. By optimizing the splitting results, we solve the problem of textons in HRRS images existing in different scales. At fine level, we employ fuzzy classification segmentation techniques with adjusted parameters for different land cover. We implement our algorithm using real world 1-foot resolution aerial images. Second, we devise methodologies to automatically annotate HRRS images based on semantics. In this, we address the issue of semantic feature selection, the major challenge faced by semantic-based image retrieval. To discover and make use of hidden semantics of images is application dependent. One type of the semantics in HRRS image is conveyed by composite

  20. Towards a High-Resolution Global Inundation Delineation Dataset

    Science.gov (United States)

    Fluet-Chouinard, E.; Lehner, B.

    2011-12-01

    Although their importance for biodiversity, flow regulation and ecosystem service provision is widely recognized, wetlands and temporarily inundated landscapes remain poorly mapped globally because of their inherent elusive nature. Inventorying of wetland resources has been identified in international agreements as an essential component of appropriate conservation efforts and management initiatives of these threatened ecosystems. However, despite recent advances in remote sensing surface water monitoring, current inventories of surface water variations remain incomplete at the regional-to-global scale due to methodological limitations restricting truly global application. Remote sensing wetland applications such as SAR L-band are particularly constrained by image availability and heterogeneity of acquisition dates, while coarse resolution passive microwave and multi-sensor methods cannot discriminate distinct surface water bodies. As a result, the most popular global wetland dataset remains to this day the Global Lake & Wetland Database (Lehner and Doll, 2004) a spatially inconsistent database assembled from various existing data sources. The approach taken in this project circumvents the limitations of current global wetland monitoring methods by combining globally available topographic and hydrographic data to downscale coarse resolution global inundation data (Prigent et al., 2007) and thus create a superior inundation delineation map product. The developed procedure downscales inundation data from the coarse resolution (~27km) of current passive microwave sensors to the finer spatial resolution (~500m) of the topographic and hydrographic layers of HydroSHEDS' data suite (Lehner et al., 2006), while retaining the high temporal resolution of the multi-sensor inundation dataset. From the downscaling process emerges new information on the specific location of inundation, but also on its frequency and duration. The downscaling algorithm employs a decision tree

  1. Quench properties of high current superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Garber, M; Sampson, W B

    1980-01-01

    A technique has been developed which allows the simultaneous determination of most of the important parameters of a high current superconductor. The critical current, propagation velocity, normal state resistivity, magnetoresistance, and enthalpy are determined as a function of current and applied field. The measurements are made on non-inductive samples which simulate conditions in full scale magnets. For wide, braided conductors the propagation velocity was found to vary approximately quadratically with current in the 2 to 5 kA region. A number of conductors have been tested including some Nb/sub 3/Sn braids which have critical currents in excess of 10 kA at 5 T, 4.2 K.

  2. A high-resolution time-to-digital converter using a three-level resolution

    Science.gov (United States)

    Dehghani, Asma; Saneei, Mohsen; Mahani, Ali

    2016-08-01

    In this article, a three-level resolution Vernier delay line time-to-digital converter (TDC) was proposed. The proposed TDC core was based on the pseudo-differential digital architecture that made it insensitive to nMOS and pMOS transistor mismatches. It also employed a Vernier delay line (VDL) in conjunction with an asynchronous read-out circuitry. The time interval resolution was equal to the difference of delay between buffers of upper and lower chains. Then, via the extra chain included in the lower delay line, resolution was controlled and power consumption was reduced. This method led to high resolution and low power consumption. The measurement results of TDC showed a resolution of 4.5 ps, 12-bit output dynamic range, and integral nonlinearity of 1.5 least significant bits. This TDC achieved the consumption of 68.43 µW from 1.1-V supply.

  3. Updating Maps Using High Resolution Satellite Imagery

    Science.gov (United States)

    Alrajhi, Muhamad; Shahzad Janjua, Khurram; Afroz Khan, Mohammad; Alobeid, Abdalla

    2016-06-01

    Kingdom of Saudi Arabia is one of the most dynamic countries of the world. We have witnessed a very rapid urban development's which are altering Kingdom's landscape on daily basis. In recent years a substantial increase in urban populations is observed which results in the formation of large cities. Considering this fast paced growth, it has become necessary to monitor these changes, in consideration with challenges faced by aerial photography projects. It has been observed that data obtained through aerial photography has a lifecycle of 5-years because of delay caused by extreme weather conditions and dust storms which acts as hindrances or barriers during aerial imagery acquisition, which has increased the costs of aerial survey projects. All of these circumstances require that we must consider some alternatives that can provide us easy and better ways of image acquisition in short span of time for achieving reliable accuracy and cost effectiveness. The approach of this study is to conduct an extensive comparison between different resolutions of data sets which include: Orthophoto of (10 cm) GSD, Stereo images of (50 cm) GSD and Stereo images of (1 m) GSD, for map updating. Different approaches have been applied for digitizing buildings, roads, tracks, airport, roof level changes, filling stations, buildings under construction, property boundaries, mosques buildings and parking places.

  4. Sunspot Group Development in High Resolution

    CERN Document Server

    Muraközy, J; Ludmány, A

    2014-01-01

    The Solar and Heliospheric Obseratory/Michelson Doppler Imager--Debrecen Data (SDD) sunspot catalogue provides an opportunity to study the details and development of sunspot groups on a large statistical sample. The SDD data allow, in particular, the differential study of the leading and following parts with a temporal resolution of 1.5 hours. In this study, we analyse the equilibrium distance of sunspot groups as well as the evolution of this distance over the lifetime of the groups and the shifts in longitude associated with these groups. We also study the asymmetry between the compactness of the leading and following parts, as well as the time-profiles for the development of the area of sunspot groups. A logarithmic relationship has been found between the total area and the distance of leading-following parts of active regions (ARs) at the time of their maximum area. In the developing phase the leading part moves forward; this is more noticeable in larger ARs. The leading part has a higher growth rate than...

  5. Wide-field, high-resolution Fourier ptychographic microscopy

    CERN Document Server

    Zheng, Guoan; Yang, Changhuei

    2014-01-01

    In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field, high-resolution complex sample image. By adopting a wavefront correction strategy, the FPM method can also correct for aberrations and digitally extend a microscope's depth-of-focus beyond the physical limitations of its optics. As a demonstration, we built a microscope prototype with a resolution of 0.78 um, a field-of-view of ~120 mm2, and a resolution-invariant depth-of-focus of 0.3 mm (characterized at 632 nm). Gigapixel colour images of histology slides verify FPM's successful operation. The reported imaging procedure transforms the general challenge of high-throughput, high-resolution microscopy from one that is coupled to the physical limitations of the system's optics to one that is solvable through computation.

  6. A revisit on the current practice of dispute resolution and ADR in the Malaysian construction industry

    Directory of Open Access Journals (Sweden)

    Mohd Suhaimi Mohd Danuri

    2012-06-01

    Full Text Available The current dispute resolution procedures available in the Malaysian construction industry are mainly litigation and arbitration. In addition, the alternative dispute resolutions (ADR, namely mediation and adjudication, have also been introduced as the other methods for resolving disputes. The objective of this study is to examine the current practice of dispute resolution and ADR available in the Malaysian construction industry. The aim of this paper is two-fold: to report the current practice of dispute resolution and ADR, and identify the attributes of successful implementation of both mechanisms based on the perceptions of the Malaysian construction industry players. From the jurisprudence point of view, this study looks into the law as it is, in relation to the current practice of dispute resolution and ADR, by showing how those findings can be used to explain why improvement is needed to promote a successful and well received dispute resolution and ADR, and what lessons can be learnt, towards the formulation of a more viable methods for the Malaysian construction industry. NVivo software has been used to manage and organise the complete interview transcripts and facilitate the data analysis process for this study. Literature review reveals a continuous development of dispute resolution and ADR in the Malaysian construction industry, while, globally the industry has not only embraced ADR but also spearheaded the development of innovative forms of dispute avoidance mechanism. The findings of interviews show that locally, apart from litigation, the common types of ADR are arbitration, mediation and ad hoc mechanism. The findings also lead to the discovery of the following attributes: faster, less procedural, cost effective and enforceable; regulation and government's support; professionalism and ethic; training; and facility, that may promote a successful implementation of dispute resolution and ADR in Malaysia.

  7. High resolution mid-infrared spectroscopy based on frequency upconversion

    DEFF Research Database (Denmark)

    Dam, Jeppe Seidelin; Hu, Qi; Tidemand-Lichtenberg, Peter

    2013-01-01

    We present high resolution upconversion of incoherent infrared radiation by means of sum-frequency mixing with a laser followed by simple CCD Si-camera detection. Noise associated with upconversion is, in strong contrast to room temperature direct mid-IR detection, extremely small, thus very faint...... signals can be analyzed. The obtainable frequency resolution is usually in the nm range where sub nm resolution is preferred in many applications, like gas spectroscopy. In this work we demonstrate how to obtain sub nm resolution when using upconversion. In the presented realization one object point...

  8. Achieving High Resolution Timer Events in Virtualized Environment.

    Science.gov (United States)

    Adamczyk, Blazej; Chydzinski, Andrzej

    2015-01-01

    Virtual Machine Monitors (VMM) have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service). Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  9. A dedicated high resolution PET imager for plant sciences

    CERN Document Server

    Wang, Qiang; Li, Ke; Wen, Jie; Komarov, Sergey; O'Sullivan, Joseph A; Tai, Yuan-Chuan

    2014-01-01

    PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high spatial resolution, housed in a fully controlled environment provided by a plant growth chamber (PGC). The system currently contains two types of detector modules: 84 microPET R4 block detectors with 2.2 mm crystals to provide a large detecting area; and 32 Inveon block detectors with 1.5 mm crystals to provide higher spatial resolution. Outputs of the four microPET block detectors in a modular housing are concatenated by a custom printed circuit board to match the output characteristics of an Inveon detector. All the detectors are read out by QuickSilver electronics. The detector modules are configured to full rings with a 15 cm diameter trans-axial field of view (FOV) for dynamic tomographic imaging of small plants. Potentially, the Inveon detectors can be reconfigured to qua...

  10. High-Resolution Observations of a Binary Black Hole Candidate

    Science.gov (United States)

    Tsai, Chao-Wei; Phillips, Chris; Norris, Ray; Jarrett, Thomas; Emonts, Bjorn; Cluver, Michelle; Eisenhardt, Peter; Stern, Daniel; Assef, Roberto

    2012-10-01

    We propose a 12-hour 2.3 GHz continuum Long Baseline Array (LBA) observation of WISE J2332-5056, a newly discovered supermassive black hole (SMBH) merger candidate that is located in the nearby universe (z = 0.3447). Our recently acquired 9 GHz ATCA map shows unusual radio morphology: a one-sided, smaller (and likely younger) FR-I jet perpendicular to a larger, Doppler-boosted FR-II jet. Follow-up Gemini-S/GMOS spectroscopy of this WISE-selected radio galaxy reveals broad emission lines blue-shifted by > 3,500 km/s with respect to the narrow lines and host galaxy, hallmarks of a dual AGN system. Combined, the optical spectroscopy and radio morphology of this object are strongly suggestive of a black hole merger system. Even in the local universe these systems are extremely difficult to identify; yet the process of supermassive blackhole growth is vital toward understanding galaxy evolution from the early to the current universe. Moreover, nearby merging SMBHs may serve as outstanding targets for gravitational wave studies. The proposed high resolution LBA map, reaching 50 pc resolution at the source redshift will allow us to investigate the SMBH merger scenario hypothesis.

  11. High-resolution spectroscopy of gases for industrial applications

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    High-resolution spectroscopy of gases is a powerful technique which has various fundamental and practical applications: in situ simultaneous measurements of gas temperature and gas composition, radiative transfer modeling, validation of existing and developing of new databases and etc. Existing...... to, for example, atmospheric research, combustion and gasification. Some high-temperature, high-resolution IR/UV absorption/transmission measurements gases (e.g. CO2, SO2, SO3 and phenol) are presented....

  12. Development and Characterization of a High Resolution Portable Gamma Spectrometer

    Science.gov (United States)

    Ali, Muhammad

    The recent disaster of Fukushima in Japan combined with the high demand to enhance nuclear safety and to minimize personal exposure to radioactive materials has a significant impact on research and development of radiation detection instrumentation. Currently, there is ample effort worldwide in the pursuit of radiation detection to maximize the accuracy and meet international standards in terms of size and specifications to enable radiation protection decision making. Among the requirements is the development of a portable, light-weight gamma-ray isotope identifier to be used by first responders in nuclear accidents as well as for radiation security and identification of illicit material isotopes. From nuclear security perspective, research into advanced screening technologies has become a high priority in all aspects, while for occupational safety, and environmental radiation protection, the regulatory authorities are requiring specific performance of radiation detection and measuring devices. At the applied radiation laboratory of the University of Ontario Institute of Technology, UOIT, the development of a high resolution spectrometer for medium and high energy gamma ray has been conducted. The spectrometer used a newly developed scintillator based on a LaBr3(Ce) crystal. The detector has been modeled using advanced Monte Carlo code (MCNP/X code) for the response function simulation and parameter characterization. The simulation results have been validated by experimental investigations using a wide range of gamma radiation energies. The developed spectrometer has been characterized in terms of resolution and response in different fields. It has also been compared with other crystals such as NaI(TI) and LiI(Eu).

  13. A new high resolution tidal model in the arctic ocean

    DEFF Research Database (Denmark)

    Cancet, M.; Andersen, Ole Baltazar; Lyard, F.

    The Arctic Ocean is a challenging region for tidal modeling, because of its complex and not well-documented bathymetry, together combined with the intermittent presence of sea ice and the fact that the in situ tidal observations are rather scarce at such high latitudes. As a consequence, the accu......The Arctic Ocean is a challenging region for tidal modeling, because of its complex and not well-documented bathymetry, together combined with the intermittent presence of sea ice and the fact that the in situ tidal observations are rather scarce at such high latitudes. As a consequence...... of the tides improves the quality of the high latitudes altimeter sea surface heights and of all derived products, such as the altimetry-derived geostrophic currents, the mean sea surface and the mean dynamic topography. In addition, accurate tidal models are highly strategic information for ever......-growing maritime and industrial activities in this region. NOVELTIS and DTU Space have developed a regional, high-resolution tidal atlas in the Arctic Ocean, in the framework of the CryoSat Plus for Ocean (CP4O) ESA project. In particular, this atlas benefits from the assimilation of the most complete satellite...

  14. A multi-channel high time resolution detector for high content imaging

    CERN Document Server

    Lapington, J S; Miller, G M; Ashton, T J R; Jarron, P; Despeisse, M; Powolny, F; Howorth, J; Milnes, J

    2009-01-01

    Medical imaging has long benefited from advances in photon counting detectors arising from space and particle physics. We describe a microchannel plate-based detector system for high content (multi-parametric) analysis, specifically designed to provide a step change in performance and throughput for measurements in imaged live cells and tissue for the ‘omics’. The detector system integrates multi-channel, high time resolution, photon counting capability into a single miniaturized detector with integrated ASIC electronics, comprising a fast, low power amplifier discriminator and TDC for every channel of the discrete pixel electronic readout, and achieving a pixel density improvement of order two magnitudes compared with current comparable devices. The device combines high performance, easy reconfigurability, and economy within a compact footprint. We present simulations and preliminary measurements in the context of our ultimate goals of 20 ps time resolution with multi-channel parallel analysis (1024 chan...

  15. Development of high current electron beam generator

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byeong Cheol; Lee, Jong Min; Kim, Sun Kook [and others

    1997-05-01

    A high-current electron beam generator has been developed. The energy and the average current of the electron beam are 2 MeV and 50 mA, respectively. The electron beam generator is composed of an electron gun, RF acceleration cavities, a 260-kW RF generator, electron beam optics components, and control system, etc. The electron beam generator will be used for the development of a millimeter-wave free-electron laser and a high average power infrared free-electron laser. The machine will also be used as a user facility in nuclear industry, environment industry, semiconductor industry, chemical industry, etc. (author). 15 tabs., 85 figs.

  16. High-resolution light field reconstruction using a hybrid imaging system.

    Science.gov (United States)

    Wang, Xiang; Li, Lin; Hou, GuangQi

    2016-04-01

    Recently, light field cameras have drawn much attraction for their innovative performance in photographic and scientific applications. However, narrow baselines and constrained spatial resolution of current light field cameras impose restrictions on their usability. Therefore, we design a hybrid imaging system containing a light field camera and a high-resolution digital single lens reflex camera, and these two kinds of cameras share the same optical path with a beam splitter so as to achieve the reconstruction of high-resolution light fields. The high-resolution 4D light fields are reconstructed with a phase-based perspective variation strategy. First, we apply complex steerable pyramid decomposition on the high-resolution image from the digital single lens reflex camera. Then, we perform phase-based perspective-shift processing with the disparity value, which is extracted from the upsampled light field depth map, to create high-resolution synthetic light field images. High-resolution digital refocused images and high-resolution depth maps can be generated in this way. Furthermore, controlling the magnitude of the perspective shift enables us to change the depth of field rendering in the digital refocused images. We show several experimental results to demonstrate the effectiveness of our approach.

  17. Spatially adaptive regularized iterative high-resolution image reconstruction algorithm

    Science.gov (United States)

    Lim, Won Bae; Park, Min K.; Kang, Moon Gi

    2000-12-01

    High resolution images are often required in applications such as remote sensing, frame freeze in video, military and medical imaging. Digital image sensor arrays, which are used for image acquisition in many imaging systems, are not dense enough to prevent aliasing, so the acquired images will be degraded by aliasing effects. To prevent aliasing without loss of resolution, a dense detector array is required. But it may be very costly or unavailable, thus, many imaging systems are designed to allow some level of aliasing during image acquisition. The purpose of our work is to reconstruct an unaliased high resolution image from the acquired aliased image sequence. In this paper, we propose a spatially adaptive regularized iterative high resolution image reconstruction algorithm for blurred, noisy and down-sampled image sequences. The proposed approach is based on a Constrained Least Squares (CLS) high resolution reconstruction algorithm, with spatially adaptive regularization operators and parameters. These regularization terms are shown to improve the reconstructed image quality by forcing smoothness, while preserving edges in the reconstructed high resolution image. Accurate sub-pixel motion registration is the key of the success of the high resolution image reconstruction algorithm. However, sub-pixel motion registration may have some level of registration error. Therefore, a reconstruction algorithm which is robust against the registration error is required. The registration algorithm uses a gradient based sub-pixel motion estimator which provides shift information for each of the recorded frames. The proposed algorithm is based on a technique of high resolution image reconstruction, and it solves spatially adaptive regularized constrained least square minimization functionals. In this paper, we show that the reconstruction algorithm gives dramatic improvements in the resolution of the reconstructed image and is effective in handling the aliased information. The

  18. Precision cosmology with time delay lenses: High resolution imaging requirements

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Xiao -Lei [Beijing Normal Univ., Beijing (China); Univ. of California, Santa Barbara, CA (United States); Treu, Tommaso [Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Agnello, Adriano [Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Auger, Matthew W. [Univ. of Cambridge, Cambridge (United Kingdom); Liao, Kai [Beijing Normal Univ., Beijing (China); Univ. of California, Santa Barbara, CA (United States); Univ. of California, Los Angeles, CA (United States); Marshall, Philip J. [Stanford Univ., Stanford, CA (United States)

    2015-09-28

    Lens time delays are a powerful probe of cosmology, provided that the gravitational potential of the main deflector can be modeled with sufficient precision. Recent work has shown that this can be achieved by detailed modeling of the host galaxies of lensed quasars, which appear as ``Einstein Rings'' in high resolution images. The distortion of these arcs and counter-arcs, as measured over a large number of pixels, provides tight constraints on the difference between the gravitational potential between the quasar image positions, and thus on cosmology in combination with the measured time delay. We carry out a systematic exploration of the high resolution imaging required to exploit the thousands of lensed quasars that will be discovered by current and upcoming surveys with the next decade. Specifically, we simulate realistic lens systems as imaged by the Hubble Space Telescope (HST), James Webb Space Telescope (JWST), and ground based adaptive optics images taken with Keck or the Thirty Meter Telescope (TMT). We compare the performance of these pointed observations with that of images taken by the Euclid (VIS), Wide-Field Infrared Survey Telescope (WFIRST) and Large Synoptic Survey Telescope (LSST) surveys. We use as our metric the precision with which the slope γ' of the total mass density profile ρtot∝ r–γ' for the main deflector can be measured. Ideally, we require that the statistical error on γ' be less than 0.02, such that it is subdominant to other sources of random and systematic uncertainties. We find that survey data will likely have sufficient depth and resolution to meet the target only for the brighter gravitational lens systems, comparable to those discovered by the SDSS survey. For fainter systems, that will be discovered by current and future surveys, targeted follow-up will be required. Furthermore, the exposure time required with upcoming facilitites such as JWST, the Keck Next Generation Adaptive

  19. Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes.

    Science.gov (United States)

    Yang, Yongfeng; Dokhale, Purushottam A; Silverman, Robert W; Shah, Kanai S; McClish, Mickel A; Farrell, Richard; Entine, Gerald; Cherry, Simon R

    2006-05-07

    We explore dual-ended read out of LSO arrays with two position sensitive avalanche photodiodes (PSAPDs) as a high resolution, high efficiency depth-encoding detector for PET applications. Flood histograms, energy resolution and depth of interaction (DOI) resolution were measured for unpolished LSO arrays with individual crystal sizes of 1.0, 1.3 and 1.5 mm, and for a polished LSO array with 1.3 mm pixels. The thickness of the crystal arrays was 20 mm. Good flood histograms were obtained for all four arrays, and crystals in all four arrays can be clearly resolved. Although the amplitude of each PSAPD signal decreases as the interaction depth moves further from the PSAPD, the sum of the two PSAPD signals is essentially constant with irradiation depth for all four arrays. The energy resolutions were similar for all four arrays, ranging from 14.7% to 15.4%. A DOI resolution of 3-4 mm (including the width of the irradiation band which is approximately 2 mm) was obtained for all the unpolished arrays. The best DOI resolution was achieved with the unpolished 1 mm array (average 3.5 mm). The DOI resolution for the 1.3 mm and 1.5 mm unpolished arrays was 3.7 and 4.0 mm respectively. For the polished array, the DOI resolution was only 16.5 mm. Summing the DOI profiles across all crystals for the 1 mm array only degraded the DOI resolution from 3.5 mm to 3.9 mm, indicating that it may not be necessary to calibrate the DOI response separately for each crystal within an array. The DOI response of individual crystals in the array confirms this finding. These results provide a detailed characterization of the DOI response of these PSAPD-based PET detectors which will be important in the design and calibration of a PET scanner making use of this detector approach.

  20. High resolution spectrograph for the 4MOST facility

    Science.gov (United States)

    Mignot, Shan; Amans, Jean-Philippe; Cohen, Mathieu; Horville, David; Jagourel, Pascal

    2012-09-01

    4MOST (4-metre Multi-Object Spectrograph Telescope) is a wide field and high multiplex fibre-fed spectroscopic facility continuously running a public survey on one of ESO's 4-metre telescopes (NTT or VISTA). It is currently undergoing a concept study and comprises a multi-object (300) high resolution (20 000) spectrograph whose purpose is to provide detailed chemical information in two wavelength ranges (395-456.5 nm and 587-673 nm). It will complement the data produced by ESA's space mission Gaia to form an unprecedented galactic-archaeology picture of the Milky Way as the result of the public survey. Building on the developments carried out for the GYES1 instrument on the Canada- France-Hawaii Telescope in 2010, the spectrograph is intended as being athermal and not featuring any motorised parts for high reliability and minimum maintenance, thereby allowing it to operate every night for five years. In addition to the fixed configuration which allows fine-tuning the spectrograph to a precise need, it features a dual-arm architecture with volume-phase holographic gratings to achieve the required dispersion at a maximum efficiency in each channel. By combining high yield time-wise and photon-wise, the spectrograph is expected to deliver more than a million spectra and make the most out of the selected 4-metre telescope.

  1. High Resolution CryoFESEM of Microbial Surfaces

    Science.gov (United States)

    Erlandsen, Stanley; Lei, Ming; Martin-Lacave, Ines; Dunny, Gary; Wells, Carol

    2003-08-01

    The outer surfaces of three microorganisms, Giardia lamblia, Enterococcus faecalis, and Proteus mirabilis, were investigated by cryo-immobilization followed by sublimation of extracellular ice and cryocoating with either Pt alone or Pt plus carbon. Cryocoated samples were examined at [minus sign]125°C in either an in-lens field emission SEM or a below-the-lens field emission SEM. Cryocoating with Pt alone was sufficient for low magnification observation, but attempts to do high-resolution imaging resulted in radiolysis and cracking of the specimen surface. Double coating with Pt and carbon, in combination with high resolution backscatter electron detectors, enabled high-resolution imaging of the glycocalyx of bacteria, revealing a sponge-like network over the surface. High resolution examination of bacterial flagella also revealed a periodic substructure. Common artifacts included radiolysis leading to “cracking” of the surface, and insufficient deposition of Pt resulting in the absence of detectable surface topography.

  2. High Resolution Orthoimagery = Orthorectified Metro Areas: 2000 - Present

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — High resolution orthorectified images combine the image characteristics of an aerial photograph with the geometric qualities of a map. An orthoimage is a...

  3. High-resolution SPECT for small-animal imaging

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    This article presents a brief overview of the development of high-resolution SPECT for small-animal imaging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pinhole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection efficiency.

  4. Methodology of high-resolution photography for mural condition database

    Science.gov (United States)

    Higuchi, R.; Suzuki, T.; Shibata, M.; Taniguchi, Y.

    2015-08-01

    Digital documentation is one of the most useful techniques to record the condition of cultural heritage. Recently, high-resolution images become increasingly useful because it is possible to show general views of mural paintings and also detailed mural conditions in a single image. As mural paintings are damaged by environmental stresses, it is necessary to record the details of painting condition on high-resolution base maps. Unfortunately, the cost of high-resolution photography and the difficulty of operating its instruments and software have commonly been an impediment for researchers and conservators. However, the recent development of graphic software makes its operation simpler and less expensive. In this paper, we suggest a new approach to make digital heritage inventories without special instruments, based on our recent our research project in Üzümlü church in Cappadocia, Turkey. This method enables us to achieve a high-resolution image database with low costs, short time, and limited human resources.

  5. High Resolution Screening of biologically active compounds and metabolites

    NARCIS (Netherlands)

    Kool, J.

    2007-01-01

    High Resolution Screening of biologically active compounds and metabolites Jeroen Kool Biotransformation enzymes play a crucial role in the metabolism of both endogenous compounds and xenobiotics. Usually, the detoxication of these compounds by biotransformation enzymes results in harmless metab

  6. NOAA High-Resolution Sea Surface Temperature (SST) Analysis Products

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This archive covers two high resolution sea surface temperature (SST) analysis products developed using an optimum interpolation (OI) technique. The analyses have a...

  7. High Resolution, Range/Range-Rate Imager Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Visidyne proposes to develop a design for a small, lightweight, high resolution, in x, y, and z Doppler imager to assist in the guidance, navigation and control...

  8. Using High Spatial Resolution Digital Imagery

    Science.gov (United States)

    2005-02-01

    frame and a bright area (hot spot) at the center. The same brightness shifts are present within most aerial photography , particularly the pronounced hot...the deciduous trees and shrubs were without leaves. In addition, the reed and grass species were fully senesced . The lack of photosynthetically...For example, high quality, large-scale aerial photography will provide adequate clarity and detail to accurately identify surface features that are

  9. High resolution survey for topographic surveying

    Science.gov (United States)

    Luh, L. C.; Setan, H.; Majid, Z.; Chong, A. K.; Tan, Z.

    2014-02-01

    In this decade, terrestrial laser scanner (TLS) is getting popular in many fields such as reconstruction, monitoring, surveying, as-built of facilities, archaeology, and topographic surveying. This is due the high speed in data collection which is about 50,000 to 1,000,000 three-dimensional (3D) points per second at high accuracy. The main advantage of 3D representation for the data is that it is more approximate to the real world. Therefore, the aim of this paper is to show the use of High-Definition Surveying (HDS), also known as 3D laser scanning for topographic survey. This research investigates the effectiveness of using terrestrial laser scanning system for topographic survey by carrying out field test in Universiti Teknologi Malaysia (UTM), Skudai, Johor. The 3D laser scanner used in this study is a Leica ScanStation C10. Data acquisition was carried out by applying the traversing method. In this study, the result for the topographic survey is under 1st class survey. At the completion of this study, a standard of procedure was proposed for topographic data acquisition using laser scanning systems. This proposed procedure serves as a guideline for users who wish to utilize laser scanning system in topographic survey fully.

  10. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...... resolution haptic patterns so that they translate naturally to the user’s haptic experience. To solve this question we have developed and tested several visual editors...

  11. High resolution computed tomography for peripheral facial nerve paralysis

    Energy Technology Data Exchange (ETDEWEB)

    Koester, O.; Straehler-Pohl, H.J.

    1987-01-01

    High resolution computer tomographic examinations of the petrous bones were performed on 19 patients with confirmed peripheral facial nerve paralysis. High resolution CT provides accurate information regarding the extent, and usually regarding the type, of pathological process; this can be accurately localised with a view to possible surgical treatments. The examination also differentiates this from idiopathic paresis, which showed no radiological changes. Destruction of the petrous bone, without facial nerve symptoms, makes early suitable treatment mandatory.

  12. Geometric calibration of high-resolution remote sensing sensors

    Institute of Scientific and Technical Information of China (English)

    LIANG Hong-you; GU Xing-fa; TAO Yu; QIAO Chao-fei

    2007-01-01

    This paper introduces the applications of high-resolution remote sensing imagery and the necessity of geometric calibration for remote sensing sensors considering assurance of the geometric accuracy of remote sensing imagery. Then the paper analyzes the general methodology of geometric calibration. Taking the DMC sensor geometric calibration as an example, the paper discusses the whole calibration procedure. Finally, it gave some concluding remarks on geometric calibration of high-resolution remote sensing sensors.

  13. Scalable Algorithms for Large High-Resolution Terrain Data

    DEFF Research Database (Denmark)

    Mølhave, Thomas; Agarwal, Pankaj K.; Arge, Lars Allan

    2010-01-01

    In this paper we demonstrate that the technology required to perform typical GIS computations on very large high-resolution terrain models has matured enough to be ready for use by practitioners. We also demonstrate the impact that high-resolution data has on common problems. To our knowledge, some...... of the computations we present have never before been carried out by standard desktop computers on data sets of comparable size....

  14. A dedicated high-resolution PET imager for plant sciences.

    Science.gov (United States)

    Wang, Qiang; Mathews, Aswin J; Li, Ke; Wen, Jie; Komarov, Sergey; O'Sullivan, Joseph A; Tai, Yuan-Chuan

    2014-10-07

    PET provides an in vivo molecular and functional imaging capability that could be valuable for studying the interaction of plants in changing environments at the whole-plant level. We have developed a dedicated plant PET imager housed in a plant growth chamber (PGC), which provides a fully controlled environment. The system currently contains two types of scintillation detector modules from commercial small animal PET scanners: 84 microPET® detectors, which are made with scintillation crystal arrays of 2.2 mm(3) × 2.2 mm(3) × 10 mm(3) crystals to provide a large detection area; and 32 Inveon™ detectors, which are made with scintillation crystal arrays of 1.5 mm(3) × 1.5 mm(3) × 10 mm(3) crystals to provide higher spatial resolution. The detector modules are configured to form two half-rings, which provide a 15 cm-diameter trans-axial field of view (FOV) for dynamic tomographic imaging of small plants. Alternatively, the Inveon detectors can be reconfigured to form quarter-rings, which provide a 25 cm FOV using step-and-shoot motion. The imager contains two linear stages that move detectors vertically at different heights for multisection scanning, and two rotation stages to collect coincidence events from all angles when using the step-and-shoot acquisition. The detector modules and mechanical components of the imager are housed inside a PGC that regulates the environmental parameters. The system has a typical energy resolution of 15% for the Inveon detectors and 24% for the microPET detectors, timing resolution of 1.8 ns, and sensitivity of 1.3%, 1.4% and 3.0% measured at the center of the FOV, 5 cm off to the larger half-ring and 5 cm off to the smaller half-ring, respectively (with a 350-650 keV energy window and 3.1 ns timing window). The system's spatial resolution is capable of resolving rod sources of 1.25 mm diameter spaced 2.5 mm apart (center to center) using the ML-EM reconstruction algorithm. Preliminary imaging experiments

  15. Dynamics of High-Resolution Networks

    DEFF Research Database (Denmark)

    Sekara, Vedran

    NETWORKS are everywhere. From the smallest confines of the cells within our bodies to the webs of social relations across the globe. Networks are not static, they constantly change, adapt, and evolve to suit new conditions. In order to understand the fundamental laws that govern networks we need...... the unprecedented amounts of information collected by mobile phones to gain detailed insight into the dynamics of social systems. This dissertation presents an unparalleled data collection campaign, collecting highly detailed traces for approximately 1000 people over the course of multiple years. The availability...

  16. High resolution multi-scalar drought indices for Iberia

    Science.gov (United States)

    Russo, Ana; Gouveia, Célia; Trigo, Ricardo; Jerez, Sonia

    2014-05-01

    The Iberian Peninsula has been recurrently affected by drought episodes and by adverse associated effects (Gouveia et al., 2009), ranging from severe water shortages to losses of hydroelectricity production, increasing risk of forest fires, forest decline and triggering processes of land degradation and desertification. Moreover, Iberia corresponds to one of the most sensitive areas to current and future climate change and is nowadays considered a hot spot of climate change with high probability for the increase of extreme events (Giorgi and Lionello, 2008). The spatial and temporal behavior of climatic droughts at different time scales was analyzed using spatially distributed time series of multi-scalar drought indicators, such as the Standardized Precipitation Evapotranspiration Index (SPEI) (Vicente-Serrano et al., 2010). This new climatic drought index is based on the simultaneous use of precipitation and temperature fields with the advantage of combining a multi-scalar character with the capacity to include the effects of temperature variability on drought assessment. Moreover, reanalysis data and the higher resolution hindcasted databases obtained from them are valuable surrogates of the sparse observations and widely used for in-depth characterizations of the present-day climate. Accordingly, this work aims to enhance the knowledge on high resolution drought patterns in Iberian Peninsula, taking advantage of high-resolution (10km) regional MM5 simulations of the recent past (1959-2007) over Iberia. It should be stressed that these high resolution meteorological fields (e.g. temperature, precipitation) have been validated for various purposes (Jerez et al., 2013). A detailed characterization of droughts since the 1960s using the 10 km resolution hidncasted simulation was performed with the aim to explore the conditions favoring drought onset, duration and ending, as well as the subsequent short, medium and long-term impacts affecting the environment and the

  17. High resolution 3-D wavelength diversity imaging

    Science.gov (United States)

    Farhat, N. H.

    1981-09-01

    A physical optics, vector formulation of microwave imaging of perfectly conducting objects by wavelength and polarization diversity is presented. The results provide the theoretical basis for optimal data acquisition and three-dimensional tomographic image retrieval procedures. These include: (a) the selection of highly thinned (sparse) receiving array arrangements capable of collecting large amounts of information about remote scattering objects in a cost effective manner and (b) techniques for 3-D tomographic image reconstruction and display in which polarization diversity data is fully accounted for. Data acquisition employing a highly attractive AMTDR (Amplitude Modulated Target Derived Reference) technique is discussed and demonstrated by computer simulation. Equipment configuration for the implementation of the AMTDR technique is also given together with a measurement configuration for the implementation of wavelength diversity imaging in a roof experiment aimed at imaging a passing aircraft. Extension of the theory presented to 3-D tomographic imaging of passive noise emitting objects by spectrally selective far field cross-correlation measurements is also given. Finally several refinements made in our anechoic-chamber measurement system are shown to yield drastic improvement in performance and retrieved image quality.

  18. High current ion source development at Frankfurt

    Energy Technology Data Exchange (ETDEWEB)

    Volk, K.; Klein, H.; Lakatos, A.; Maaser, A.; Weber, M. [Frankfurt Univ. (Germany). Inst. fuer Angewandte Physik

    1995-11-01

    The development of high current positive and negative ion sources is an essential issue for the next generation of high current linear accelerators. Especially, the design of the European Spallation Source facility (ESS) and the International Fusion Material Irradiation Test Facility (IFMIF) have increased the significance of high brightness hydrogen and deuterium sources. As an example, for the ESS facility, two H{sup -}-sources each delivering a 70 mA H{sup -}-beam in 1.45 ms pulses at a repetition rate of 50 Hz are necessary. A low emittance is another important prerequisite. The source must operate, while meeting the performance requirements, with a constancy and reliability over an acceptable period of time. The present paper summarizes the progress achieved in ion sources development of intense, single charge, positive and negative ion beams. (author) 16 figs., 7 refs.

  19. High-resolution field shaping utilizing a masked multileaf collimator.

    Science.gov (United States)

    Williams, P C; Cooper, P

    2000-08-01

    Multileaf collimators (MLCs) have become an important tool in the modern radiotherapy department. However, the current limit of resolution (1 cm at isocentre) can be too coarse for acceptable shielding of all fields. A number of mini- and micro-MLCs have been developed, with thinner leaves to achieve approved resolution. Currently however, such devices are limited to modest field sizes and stereotactic applications. This paper proposes a new method of high-resolution beam collimation by use of a tertiary grid collimator situated below the conventional MLC. The width of each slit in the grid is a submultiple of the MLC width. A composite shaped field is thus built up from a series of subfields, with the main MLC defining the length of each strip within each subfield. Presented here are initial findings using a prototype device. The beam uniformity achievable with such a device was examined by measuring transmission profiles through the grid using a diode. Profiles thus measured were then copied and superposed to generate composite beams, from which the uniformity achievable could be assessed. With the average dose across the profile normalized to 100%, hot spots up to 5.0% and troughs of 3% were identified for a composite beam of 2 x 5.0 mm grids, as measured at Dmax for a 6 MV beam. For a beam composed from 4 x 2.5 mm grids, the maximum across the profile was 3.0% above the average, and the minimum 2.5% below. Actual composite profiles were also formed using the integrating properties of film, with the subfield indexing performed using an engineering positioning stage. The beam uniformity for these fields compared well with that achieved in theory using the diode measurements. Finally sine wave patterns were generated to demonstrate the potential improvements in field shaping and conformity using this device as opposed to the conventional MLC alone. The scalloping effect on the field edge commonly seen on MLC fields was appreciably reduced by use of 2 x 5.0 mm

  20. High-resolution gravity model of Venus

    Science.gov (United States)

    Reasenberg, R. D.; Goldberg, Z. M.

    1992-01-01

    The anomalous gravity field of Venus shows high correlation with surface features revealed by radar. We extract gravity models from the Doppler tracking data from the Pioneer Venus Orbiter by means of a two-step process. In the first step, we solve the nonlinear spacecraft state estimation problem using a Kalman filter-smoother. The Kalman filter has been evaluated through simulations. This evaluation and some unusual features of the filter are discussed. In the second step, we perform a geophysical inversion using a linear Bayesian estimator. To allow an unbiased comparison between gravity and topography, we use a simulation technique to smooth and distort the radar topographic data so as to yield maps having the same characteristics as our gravity maps. The maps presented cover 2/3 of the surface of Venus and display the strong topography-gravity correlation previously reported. The topography-gravity scatter plots show two distinct trends.

  1. Exploring for subtle traps with high-resolution paleogeographic maps

    Energy Technology Data Exchange (ETDEWEB)

    Bulling, T.B.; Breyer, J.A.

    1988-01-01

    High-resolution paleogeographic maps depicting the depositional history of the Reklaw 1 interval provide a basis for prospecting for subtle traps in the updip Reklaw trend in south Texas. The Reklaw 1 interval began with sand being carried southwest by longshore currents to form the barrier bar that forms the reservoir in Atkinson field. The hydrocarbons are trapped by the updip pinch-out of barrier-bar sand into lagoonal mud. Stratigraphic traps similar to Atkinson field could be present along depositional strike if the sand in the field were part of a more extensive-bar system. After the barrier bar formed, distributary-mouth bars prograded seaward depositing the bar-finger sands that are the reservoirs in Hysaw and Flax fields. Subtle structural traps could be present where small down-to-the-north faults associated with the Sample fault system cut the bar-finger sands downdip from the established production. Farther down paleoslope, the distributary channels began to bifurcate and the distributary-mouth bar coalesced to form a broad delt-front sheet sand. Burnell, Hondo Creek, and Runge West fields produce from this sheet sand near the unstable shelf margin. A rapid rise in relative sea level terminated deposition of the Reklaw 1 interval. Many of the oil and gas fields remaining to be discovered in the United States are in mature petroleum provinces where much of the remaining oil and gas probably resides in subtle traps. High-resolution paleogeographic maps may be a key to finding these subtle traps.

  2. High-resolution spectroscopy of gamma-ray transients

    Energy Technology Data Exchange (ETDEWEB)

    Cline, T.L.

    1988-09-25

    The first high-resolution spectrometer flown to observe gamma-ray bursts was launched on the ISEE-3 spacecraft over nine years ago. It recorded two events before instrument failure, giving results that were suggestive but marginal. Other studies, with coarser energy resolution, also show evidence for spectral features as well as for spectral evolution on short time scales. Absolute source strength calibration will be possible only with source identification, but understanding of the burst emission processes will surely come only from the measurements having the best spectral and temporal precision. The only high- resolution gamma-ray spectrometer now planned, here or abroad, for space flight is an instrument sequel to the ISEE-3 spectrometer, to be flown on the interplanetary 'GGS Wind' mission. Much larger and higher-sensitivity, high-resolution instruments may have their optimum opportunities in conjunction with studies of solar flares in the time frame of the solar maximum of 2002.

  3. Climatologies at high resolution for the Earth land surface areas

    CERN Document Server

    Karger, Dirk Nikolaus; Böhner, Jürgen; Kawohl, Tobias; Kreft, Holger; Soria-Auza, Rodrigo Wilber; Zimmermann, Niklaus; Linder, H Peter; Kessler, Michael

    2016-01-01

    High resolution information of climatic conditions is essential to many application in environmental sciences. Here we present the CHELSA algorithm to downscale temperature and precipitation estimates from the European Centre for Medium-Range Weather Forecast (ECMWF) climatic reanalysis interim (ERA-Interim) to a high resolution of 30 arc sec. The algorithm for temperature is based on a statistical downscaling of atmospheric temperature from the ERA-Interim climatic reanalysis. The precipitation algorithm incorporates orographic predictors such as wind fields, valley exposition, and boundary layer height, and a bias correction using Global Precipitation Climatology Center (GPCC) gridded and Global Historical Climate Network (GHCN) station data. The resulting data consist of a monthly temperature and precipitation climatology for the years 1979-2013. We present a comparison of data derived from the CHELSA algorithm with two other high resolution gridded products with overlapping temporal resolution (Tropical R...

  4. High resolution single particle refinement in EMAN2.1.

    Science.gov (United States)

    Bell, James M; Chen, Muyuan; Baldwin, Philip R; Ludtke, Steven J

    2016-05-01

    EMAN2.1 is a complete image processing suite for quantitative analysis of grayscale images, with a primary focus on transmission electron microscopy, with complete workflows for performing high resolution single particle reconstruction, 2-D and 3-D heterogeneity analysis, random conical tilt reconstruction and subtomogram averaging, among other tasks. In this manuscript we provide the first detailed description of the high resolution single particle analysis pipeline and the philosophy behind its approach to the reconstruction problem. High resolution refinement is a fully automated process, and involves an advanced set of heuristics to select optimal algorithms for each specific refinement task. A gold standard FSC is produced automatically as part of refinement, providing a robust resolution estimate for the final map, and this is used to optimally filter the final CTF phase and amplitude corrected structure. Additional methods are in-place to reduce model bias during refinement, and to permit cross-validation using other computational methods.

  5. High resolution temperature measurement technique for measuring marine heat flow

    Institute of Scientific and Technical Information of China (English)

    QIN; YangYang; YANG; XiaoQiu; WU; BaoZhen; SUN; ZhaoHua; SHI; XiaoBin

    2013-01-01

    High resolution temperature measurement technique is one of the key techniques for measuring marine heat flow. Basing on Pt1000 platinum resistance which has the characteristics of high accuracy and good stability, we designed a bridge reversal excitation circuit for high resolution temperature measurement. And the deep ocean floor in-situ test results show that: (1) temperature deviation and peak-to-peak resolution of the first version circuit board (V1) are 1.960-1.990 mK and 0.980-0.995 m Kat 1.2-2.7°C, respectively; and temperature deviation and peak-to-peak resolution of the second circuit board (V2) are 2.260mK and 1.130 mK at 1.2-1.3°C, respectively; (2) During the 2012NSFC-IndOcean cruise, seafloor geothermal gradient at Ind2012HF03,-07 and-12 stations (water depth ranges from 3841 to 4541 m) were successfully measured, the values are 59.1,75.1 and 71.6°C/km, respectively. And the measurement errors of geothermal gradient at these three stations are less than 3.0% in terms of the peak-to-peak resolution. These indicate that the high resolution temperature measurement technique based on Pt1000 platinum resistance in this paper can be applied to marine heat flow measurement to obtain high precision geothermal parameters.

  6. High resolution surface plasmon microscopy for cell imaging

    Science.gov (United States)

    Argoul, F.; Monier, K.; Roland, T.; Elezgaray, J.; Berguiga, L.

    2010-04-01

    We introduce a new non-labeling high resolution microscopy method for cellular imaging. This method called SSPM (Scanning Surface Plasmon Microscopy) pushes down the resolution limit of surface plasmon resonance imaging (SPRi) to sub-micronic scales. High resolution SPRi is obtained by the surface plasmon lauching with a high numerical aperture objective lens. The advantages of SPPM compared to other high resolution SPRi's rely on three aspects; (i) the interferometric detection of the back reflected light after plasmon excitation, (ii) the twodimensional scanning of the sample for image reconstruction, (iii) the radial polarization of light, enhancing both resolution and sensitivity. This microscope can afford a lateral resolution of - 150 nm in liquid environment and - 200 nm in air. We present in this paper images of IMR90 fibroblasts obtained with SSPM in dried environment. Internal compartments such as nucleus, nucleolus, mitochondria, cellular and nuclear membrane can be recognized without labelling. We propose an interpretation of the ability of SSPM to reveal high index contrast zones by a local decomposition of the V (Z) function describing the response of the SSPM.

  7. Liquid Scintillation High Resolution Spectral Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Grau Carles, A.; Grau Malonda, A.

    2010-08-06

    The CIEMAT/NIST and the TDCR methods in liquid scintillation counting are based on the determination of the efficiency for total counting. This paper tries to expand these methods analysing the pulse-height spectrum of radionuclides. To reach this objective we have to generalize the equations used in the model and to analyse the influence of ionization and chemical quench in both spectra and counting efficiency. We present equations to study the influence of different photomultipliers response in systems with one, two or three photomultipliers. We study the effect of the electronic noise discriminator level in both spectra and counting efficiency. The described method permits one to study problems that up to now was not possible to approach, such as the high uncertainty in the standardization of pure beta-ray emitter with low energy when we apply the TDCR method, or the discrepancies in the standardization of some electron capture radionuclides, when the CIEMAT/NIST method is applied. (Author) 107 refs.

  8. Intensity and Development Forecasts of Tropical Cyclones by the JMA High-Resolution Global NWP Model: Impacts of Resolution Enhancement

    Science.gov (United States)

    Komori, T.; Kitagawa, H.

    2007-12-01

    It is widely considered that a spatial resolution of numerical weather prediction (NWP) model plays an important role for forecasting severe weather events such as tropical cyclones (TCs) and heavy rainfall. Under the KAKUSHIN project (funded by the Japanese Ministry of Education, Culture, Sports, Science and Technology), the Japan Meteorological Agency (JMA) has developed a new Global Spectral Model (GSM) with a high horizontal resolution of about 20km and 60 vertical layers (hereafter called g20km GSMh), which is utilized to evaluate severe weather events in future climate. The 20km GSM will be operational in November 2007 replacing the current GSM with a horizontal resolution of about 60km and 40 vertical layers (hereafter called g60km GSMh). In the present study, we investigate how a model resolution impacts on TC forecasts because this resolution enhancement aims to improve the model's ability to forecast severe weather. Due to the more realistic model topography in higher horizontal resolution, the 20km GSM can give more accurate forecasts of orographic precipitation than the 60km GSM, especially over the area range of heavy precipitation. According to the statistically verified results, the enhancement of horizontal and vertical resolution appears to fairly improve the accuracy of TC intensity forecasts. However, for TC track forecasts, it may be more important to accurately represent large-scale environmental contexts surrounding the TC than to resolve the TC structure itself. In order to clarify resolution impacts on the TC intensity prediction, we categorize the TC intensity forecasts into three stages (development stage, maturation stage and dissipation stage). The results show that the effectiveness of the resolution enhancement is bigger in the development stage and relatively small in the maturation and dissipation stages. For the maturation and dissipation stages, improvement of physical processes seems to be more important than the resolution

  9. High-resolution spectroscopy of gases for industrial applications

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    High-resolution spectroscopy of gases is a powerful technique which has various fundamental and practical applications: in situ simultaneous measurements of gas temperature and gas composition, radiative transfer modeling, validation of existing and developing of new databases and etc. Existing...... for analysis of complex experimental data and further development of the databases. High-temperature gas cell facilities available at DTU Chemical Engineering are presented and described. The gas cells and high-resolution spectrometers allow us to perform high-quality reference measurements of gases relevant...

  10. High-resolution neutron microtomography with noiseless neutron counting detector

    Energy Technology Data Exchange (ETDEWEB)

    Tremsin, A.S., E-mail: ast@ssl.berkeley.edu [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); McPhate, J.B.; Vallerga, J.V.; Siegmund, O.H.W. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Feller, W.B. [Nova Scientific Inc., 10 Picker Road, Sturbridge, MA 01566 (United States); Lehmann, E. [Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Butler, L.G. [Louisiana State University, Baton Rouge, LA 70803 (United States); Dawson, M. [Helmholtz Centre Berlin for Materials and Energy (Germany)

    2011-10-01

    The improved collimation and intensity of thermal and cold neutron beamlines combined with recent advances in neutron imaging devices enable high-resolution neutron radiography and microtomography, which can provide information on the internal structure of objects not achievable with conventional X-ray imaging techniques. Neutron detection efficiency, spatial and temporal resolution (important for the studies of dynamic processes) and low background count rate are among the crucial parameters defining the quality of radiographic images and tomographic reconstructions. The unique capabilities of neutron counting detectors with neutron-sensitive microchannel plates (MCPs) and with Timepix CMOS readouts providing high neutron detection efficiency ({approx}70% for cold neutrons), spatial resolutions ranging from 15 to 55 {mu}m and a temporal resolution of {approx}1 {mu}s-combined with the virtual absence of readout noise-make these devices very attractive for high-resolution microtomography. In this paper we demonstrate the capabilities of an MCP-Timepix detection system applied to microtomographic imaging, performed at the ICON cold neutron facility of the Paul Scherrer Institute. The high resolution and the absence of readout noise enable accurate reconstruction of texture in a relatively opaque wood sample, differentiation of internal tissues of a fly and imaging of individual {approx}400 {mu}m grains in an organic powder encapsulated in a {approx}700 {mu}m thick metal casing.

  11. High Resolution Muon Computed Tomography at Neutrino Beam Facilities

    CERN Document Server

    Suerfu, Burkhant

    2015-01-01

    X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we show via simulation that muon beams can provide high resolution tomographic images of dense objects and of structures within the interior of dense objects. The effects of resolution broadening from multiple scattering diminish with increasing muon momentum. As the momentum of the muon increases, the contrast of the image goes down and therefore requires higher resolution in the muon spectrometer to resolve the image. The variance of the measured muon momentum reaches a minimum and then increases with increasing muon momentum. The impact of the increase in variance is to require a higher integrated muon flux to reduce fluctuations. The flux requirements and level of contrast needed for high resolution muon computed tomography are well matched to the muons produced in the pio...

  12. Performance of a high resolution cavity beam position monitor system

    Science.gov (United States)

    Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Honda, Yosuke; Kolomensky, Yury; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen

    2007-07-01

    It has been estimated that an RF cavity Beam Position Monitor (BPM) could provide a position measurement resolution of less than 1 nm. We have developed a high resolution cavity BPM and associated electronics. A triplet comprised of these BPMs was installed in the extraction line of the Accelerator Test Facility (ATF) at the High Energy Accelerator Research Organization (KEK) for testing with its ultra-low emittance beam. The three BPMs were each rigidly mounted inside an alignment frame on six variable-length struts which could be used to move the BPMs in position and angle. We have developed novel methods for extracting the position and tilt information from the BPM signals including a robust calibration algorithm which is immune to beam jitter. To date, we have demonstrated a position resolution of 15.6 nm and a tilt resolution of 2.1 μrad over a dynamic range of approximately ±20 μm.

  13. Resolution-recovery-embedded image reconstruction for a high-resolution animal SPECT system.

    Science.gov (United States)

    Zeraatkar, Navid; Sajedi, Salar; Farahani, Mohammad Hossein; Arabi, Hossein; Sarkar, Saeed; Ghafarian, Pardis; Rahmim, Arman; Ay, Mohammad Reza

    2014-11-01

    The small-animal High-Resolution SPECT (HiReSPECT) is a dedicated dual-head gamma camera recently designed and developed in our laboratory for imaging of murine models. Each detector is composed of an array of 1.2 × 1.2 mm(2) (pitch) pixelated CsI(Na) crystals. Two position-sensitive photomultiplier tubes (H8500) are coupled to each head's crystal. In this paper, we report on a resolution-recovery-embedded image reconstruction code applicable to the system and present the experimental results achieved using different phantoms and mouse scans. Collimator-detector response functions (CDRFs) were measured via a pixel-driven method using capillary sources at finite distances from the head within the field of view (FOV). CDRFs were then fitted by independent Gaussian functions. Thereafter, linear interpolations were applied to the standard deviation (σ) values of the fitted Gaussians, yielding a continuous map of CDRF at varying distances from the head. A rotation-based maximum-likelihood expectation maximization (MLEM) method was used for reconstruction. A fast rotation algorithm was developed to rotate the image matrix according to the desired angle by means of pre-generated rotation maps. The experiments demonstrated improved resolution utilizing our resolution-recovery-embedded image reconstruction. While the full-width at half-maximum (FWHM) radial and tangential resolution measurements of the system were over 2 mm in nearly all positions within the FOV without resolution recovery, reaching around 2.5 mm in some locations, they fell below 1.8 mm everywhere within the FOV using the resolution-recovery algorithm. The noise performance of the system was also acceptable; the standard deviation of the average counts per voxel in the reconstructed images was 6.6% and 8.3% without and with resolution recovery, respectively.

  14. Extremely High Current, High-Brightness Energy Recovery Linac

    CERN Document Server

    Ben-Zvi, Ilan; Beavis, Dana; Blaskiewicz, Michael; Bluem, Hans; Brennan, Joseph M; Burger, Al; Burrill, Andrew; Calaga, Rama; Cameron, Peter; Chang, Xiangyun; Cole, Michael; Connolly, Roger; Delayen, Jean R; Favale, Anthony; Gassner, David M; Grimes, Jacob T; Hahn, Harald; Hershcovitch, Ady; Holmes, Douglas; Hseuh Hsiao Chaun; Johnson, Peter; Kayran, Dmitry; Kewisch, Jorg; Kneisel, Peter; Lambiase, Robert; Litvinenko, Vladimir N; McIntyre, Gary; Meng, Wuzheng; Nehring, Thomas; Nicoletti, Tony; Oerter, Brian; Pate, David; Phillips, Larry; Preble, Joseph P; Rank, Jim; Rao, Triveni; Rathke, John; Roser, Thomas; Russo, Thomas; Scaduto, Joseph; Schultheiss, Tom; Segalov, Zvi; Smith, Kevin T; Todd, Alan M M; Warren-Funk, L; Williams, Neville; Wu, Kuo-Chen; Yakimenko, Vitaly; Yip, Kin; Zaltsman, Alex; Zhao, Yongxiang

    2005-01-01

    Next generation ERL light-sources, high-energy electron coolers, high-power Free-Electron Lasers, powerful Compton X-ray sources and many other accelerators were made possible by the emerging technology of high-power, high-brightness electron beams. In order to get the anticipated performance level of ampere-class currents, many technological barriers are yet to be broken. BNL's Collider-Accelerator Department is pursuing some of these technologies for its electron cooling of RHIC application, as well as a possible future electron-hadron collider. We will describe work on CW, high-current and high-brightness electron beams. This will include a description of a superconducting, laser-photocathode RF gun and an accelerator cavity capable of producing low emittance (about 1 micron rms normalized) one nano-Coulomb bunches at currents of the order of one ampere average.

  15. COMPILATION OF CURRENT HIGH ENERGY PHYSICS EXPERIMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Wohl, C.G.; Kelly, R.L.; Armstrong, F.E.; Horne, C.P.; Hutchinson, M.S.; Rittenberg, A.; Trippe, T.G.; Yost, G.P.; Addis, L.; Ward, C.E.W.; Baggett, N.; Goldschmidt-Clermong, Y.; Joos, P.; Gelfand, N.; Oyanagi, Y.; Grudtsin, S.N.; Ryabov, Yu.G.

    1981-05-01

    This is the fourth edition of our compilation of current high energy physics experiments. It is a collaborative effort of the Berkeley Particle Data Group, the SLAC library, and nine participating laboratories: Argonne (ANL), Brookhaven (BNL), CERN, DESY, Fermilab (FNAL), the Institute for Nuclear Study, Tokyo (INS), KEK, Serpukhov (SERP), and SLAC. The compilation includes summaries of all high energy physics experiments at the above laboratories that (1) were approved (and not subsequently withdrawn) before about April 1981, and (2) had not completed taking of data by 1 January 1977. We emphasize that only approved experiments are included.

  16. Developing a high-resolution regional atmospheric reanalysis for Australia

    Science.gov (United States)

    White, Christopher; Fox-Hughes, Paul; Su, Chun-Hsu; Jakob, Dörte; Kociuba, Greg; Eisenberg, Nathan; Steinle, Peter; Harris, Rebecca; Corney, Stuart; Love, Peter; Remenyi, Tomas; Chladil, Mark; Bally, John; Bindoff, Nathan

    2017-04-01

    A dynamically consistent, long-term atmospheric reanalysis can be used to support high-quality assessments of environmental risk and likelihood of extreme events. Most reanalyses are presently based on coarse-scale global systems that are not suitable for regional assessments in fire risk, water and natural resources, amongst others. The Australian Bureau of Meteorology is currently working to close this gap by producing a high-resolution reanalysis over the Australian and New Zealand region to construct a sequence of atmospheric conditions at sub-hourly intervals over the past 25 years from 1990. The Australia reanalysis consists of a convective-scale analysis nested within a 12 km regional-scale reanalysis, which is bounded by a coarse-scale ERA-Interim reanalysis that provides the required boundary and initial conditions. We use an unchanging atmospheric modelling suite based on the UERRA system used at the UK Met Office and the more recent version of the Bureau of Meteorology's operational numerical prediction model used in ACCESS-R (Australian Community Climate and Earth-System Simulator-Regional system). An advanced (4-dimensional variational) data assimilation scheme is used to optimally combine model physics with multiple observations from aircrafts, sondes, surface observations and satellites to create a best estimate of state of the atmosphere over a 6-hour moving window. This analysis is in turn used to drive a higher-resolution (1.5 km) downscaling model over selected subdomains within Australia, currently eastern New South Wales and Tasmania, with the capability to support this anywhere in the Australia-New Zealand domain. The temporal resolution of the gridded analysis fields for both the regional and higher-resolution subdomains are generally one hour, with many fields such as 10 m winds and 2 m temperatures available every 10 minutes. The reanalysis also produces many other variables that include wind, temperature, moisture, pressure, cloud cover

  17. Multi-Volume High Resolution RGB-D Mapping with Dynamic Volume Placement

    OpenAIRE

    Salvato, Michael; Finman, Ross; Leonard, John

    2015-01-01

    We present a novel RGB-D mapping system for generating 3D maps over spatially extended regions with higher resolution than current methods using multiple, dynamically placed mapping volumes. Our method takes in RGB-D frames and dynamically assigns multiple mapping volumes to the environment, exchanging mapping volumes between the CPU and GPU. Mapping volumes are added or removed as needed to allow for spatially extended, high resolution mapping. Our system is designed to maximize the resoluti...

  18. COSMIC: somatic cancer genetics at high-resolution

    Science.gov (United States)

    Forbes, Simon A.; Beare, David; Boutselakis, Harry; Bamford, Sally; Bindal, Nidhi; Tate, John; Cole, Charlotte G.; Ward, Sari; Dawson, Elisabeth; Ponting, Laura; Stefancsik, Raymund; Harsha, Bhavana; Kok, Chai Yin; Jia, Mingming; Jubb, Harry; Sondka, Zbyslaw; Thompson, Sam; De, Tisham; Campbell, Peter J.

    2017-01-01

    COSMIC, the Catalogue of Somatic Mutations in Cancer (http://cancer.sanger.ac.uk) is a high-resolution resource for exploring targets and trends in the genetics of human cancer. Currently the broadest database of mutations in cancer, the information in COSMIC is curated by expert scientists, primarily by scrutinizing large numbers of scientific publications. Over 4 million coding mutations are described in v78 (September 2016), combining genome-wide sequencing results from 28 366 tumours with complete manual curation of 23 489 individual publications focused on 186 key genes and 286 key fusion pairs across all cancers. Molecular profiling of large tumour numbers has also allowed the annotation of more than 13 million non-coding mutations, 18 029 gene fusions, 187 429 genome rearrangements, 1 271 436 abnormal copy number segments, 9 175 462 abnormal expression variants and 7 879 142 differentially methylated CpG dinucleotides. COSMIC now details the genetics of drug resistance, novel somatic gene mutations which allow a tumour to evade therapeutic cancer drugs. Focusing initially on highly characterized drugs and genes, COSMIC v78 contains wide resistance mutation profiles across 20 drugs, detailing the recurrence of 301 unique resistance alleles across 1934 drug-resistant tumours. All information from the COSMIC database is available freely on the COSMIC website. PMID:27899578

  19. High spatial resolution zonal wavefront reconstruction with improved initial value determination scheme for lateral shearing interferometry.

    Science.gov (United States)

    Dai, Fengzhao; Tang, Feng; Wang, Xiangzhao; Sasaki, Osami; Zhang, Min

    2013-06-10

    In a recent paper [J. Opt. Soc. Am. A 29, 2038 (2012)], we proposed a generalized high spatial resolution zonal wavefront reconstruction method for lateral shearing interferometry. The test wavefront can be reconstructed with high spatial resolution by using linear interpolation on a subgrid for initial values estimation. In the current paper, we utilize the difference between the Zernike polynomial fitting method and linear interpolation in determining the subgrid initial values. The validity of the proposed method is investigated through comparison with the previous high spatial resolution zonal method. Simulation results show that the proposed method is more accurate and more stable to shear ratios compared with the previous method. A comprehensive comparison of the properties of the proposed method, the previous high spatial resolution zonal method, and the modal method is performed.

  20. Isotope specific resolution recovery image reconstruction in high resolution PET imaging.

    Science.gov (United States)

    Kotasidis, Fotis A; Angelis, Georgios I; Anton-Rodriguez, Jose; Matthews, Julian C; Reader, Andrew J; Zaidi, Habib

    2014-05-01

    Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms. In this work, the authors used a printing technique to simultaneously measure multiple point sources on the High Resolution Research Tomograph (HRRT), and the authors demonstrated the feasibility of deriving isotope-dependent system matrices from fluorine-18 and carbon-11 point sources. Furthermore, the authors evaluated the impact of incorporating them within RM image reconstruction, using carbon-11 phantom and clinical datasets on the HRRT. The results obtained using these two isotopes illustrate that even small differences in positron range can result in different PSF maps, leading to further improvements in contrast recovery when used in image reconstruction. The difference is more pronounced in the centre of the field-of-view where the full width at half maximum (FWHM) from the positron range has a larger contribution to the overall FWHM compared to the edge where the parallax error dominates the overall FWHM. Based on the proposed methodology, measured isotope-specific and spatially variant PSFs can be reliably derived and used for improved spatial resolution and variance performance in resolution recovery image reconstruction. The

  1. Decadal prediction skill using a high-resolution climate model

    Science.gov (United States)

    Monerie, Paul-Arthur; Coquart, Laure; Maisonnave, Éric; Moine, Marie-Pierre; Terray, Laurent; Valcke, Sophie

    2017-02-01

    The ability of a high-resolution coupled atmosphere-ocean general circulation model (with a horizontal resolution of a quarter of a degree in the ocean and of about 0.5° in the atmosphere) to predict the annual means of temperature, precipitation, sea-ice volume and extent is assessed based on initialized hindcasts over the 1993-2009 period. Significant skill in predicting sea surface temperatures is obtained, especially over the North Atlantic, the tropical Atlantic and the Indian Ocean. The Sea Ice Extent and volume are also reasonably predicted in winter (March) and summer (September). The model skill is mainly due to the external forcing associated with well-mixed greenhouse gases. A decrease in the global warming rate associated with a negative phase of the Pacific Decadal Oscillation is simulated by the model over a suite of 10-year periods when initialized from starting dates between 1999 and 2003. The model ability to predict regional change is investigated by focusing on the mid-90's Atlantic Ocean subpolar gyre warming. The model simulates the North Atlantic warming associated with a meridional heat transport increase, a strengthening of the North Atlantic current and a deepening of the mixed layer over the Labrador Sea. The atmosphere plays a role in the warming through a modulation of the North Atlantic Oscillation: a negative sea level pressure anomaly, located south of the subpolar gyre is associated with a wind speed decrease over the subpolar gyre. This leads to a reduced oceanic heat-loss and favors a northward displacement of anomalously warm and salty subtropical water that both concur to the subpolar gyre warming. We finally conclude that the subpolar gyre warming is mainly triggered by ocean dynamics with a possible contribution of atmospheric circulation favoring its persistence.

  2. Global anthropogenic heat flux database with high spatial resolution

    Science.gov (United States)

    Dong, Y.; Varquez, A. C. G.; Kanda, M.

    2017-02-01

    This study developed a top-down method for estimating global anthropogenic heat emission (AHE), with a high spatial resolution of 30 arc-seconds and temporal resolution of 1 h. Annual average AHE was derived from human metabolic heating and primary energy consumption, which was further divided into three components based on consumer sector. The first and second components were heat loss and heat emissions from industrial sectors equally distributed throughout the country and populated areas, respectively. The third component comprised the sum of emissions from commercial, residential, and transportation sectors (CRT). Bulk AHE from the CRT was proportionally distributed using a global population dataset, with a radiance-calibrated nighttime lights adjustment. An empirical function to estimate monthly fluctuations of AHE based on gridded monthly temperatures was derived from various Japanese and American city measurements. Finally, an AHE database with a global coverage was constructed for the year 2013. Comparisons between our proposed AHE and other existing datasets revealed that the problem of overestimation of AHE intensity in previous top-down models was mitigated by the separation of energy consumption sectors; furthermore, the problem of AHE underestimation at central urban areas was solved by the nighttime lights adjustment. A strong agreement in the monthly profiles of AHE between our database and other bottom-up datasets further proved the validity of the current methodology. Investigations of AHE for the 29 largest urban agglomerations globally highlighted that the share of heat emissions from CRT sectors to the total AHE at the city level was 40-95%; whereas that of metabolic heating varied with the city's level of development by a range of 2-60%. A negative correlation between gross domestic product (GDP) and the share of metabolic heating to a city's total AHE was found. Globally, peak AHE values were found to occur between December and February, while

  3. An optimal merging technique for high-resolution precipitation products

    Directory of Open Access Journals (Sweden)

    Roshan Shrestha

    2011-12-01

    Full Text Available Precipitation products are currently available from various sources at higher spatial and temporal resolution than any time in the past. Each of the precipitation products has its strengths and weaknesses in availability, accuracy, resolution, retrieval techniques and quality control. By merging the precipitation data obtained from multiple sources, one can improve its information content by minimizing these issues. However, precipitation data merging poses challenges of scale-mismatch, and accurate error and bias assessment. In this paper we present Optimal Merging of Precipitation (OMP, a new method to merge precipitation data from multiple sources that are of different spatial and temporal resolutions and accuracies. This method is a combination of scale conversion and merging weight optimization, involving performance-tracing based on Bayesian statistics and trend-analysis, which yields merging weights for each precipitation data source. The weights are optimized at multiple scales to facilitate multiscale merging and better precipitation downscaling. Precipitation data used in the experiment include products from the 12-km resolution North American Land Data Assimilation (NLDAS system, the 8-km resolution CMORPH and the 4-km resolution National Stage-IV QPE. The test cases demonstrate that the OMP method is capable of identifying a better data source and allocating a higher priority for them in the merging procedure, dynamically over the region and time period. This method is also effective in filtering out poor quality data introduced into the merging process.

  4. High current regimes in RFX-mod

    Science.gov (United States)

    Valisa, M.; Bolzonella, T.; Buratti, P.; Carraro, L.; Cavazzana, R.; Dal Bello, S.; Martin, P.; Pasqualotto, R.; Sarff, J. S.; Spolaore, M.; Zanca, P.; Zanotto, L.; Agostini, M.; Alfier, A.; Antoni, V.; Apolloni, L.; Auriemma, F.; Barana, O.; Baruzzo, M.; Bettini, P.; Bonfiglio, D.; Bonomo, F.; Brombin, M.; Buffa, A.; Canton, A.; Cappello, S.; Cavinato, M.; Chitarin, G.; DeLorenzi, A.; DeMasi, G.; Escande, D. F.; Fassina, A.; Franz, P.; Gaio, E.; Gazza, E.; Giudicotti, L.; Gnesotto, F.; Gobbin, M.; Grando, L.; Guazzotto, L.; Guo, S. C.; Igochine, V.; Innocente, P.; Lorenzini, R.; Luchetta, A.; Manduchi, G.; Marchiori, G.; Marcuzzi, D.; Marrelli, L.; Martini, S.; Martines, E.; McCollam, K.; Milani, F.; Moresco, M.; Novello, L.; Ortolani, S.; Paccagnella, R.; Peruzzo, S.; Piovan, R.; Piron, L.; Pizzimenti, A.; Piovesan, P.; Pomaro, N.; Predebon, I.; Puiatti, M. E.; Rostagni, G.; Sattin, F.; Scarin, P.; Serianni, G.; Sonato, P.; Spada, E.; Soppelsa, A.; Spagnolo, S.; Spizzo, G.; Taliercio, C.; Terranova, D.; Toigo, V.; Vianello, N.; Yadikin, D.; Zaccaria, P.; Zaniol, B.; Zilli, E.; Zuin, M.

    2008-12-01

    Optimization of machine operation, including plasma position control, density control and especially feedback control on multiple magnetohydrodynamic modes, has led RFX-mod to operate reliably at 1.5 MA, the highest current ever achieved on a reversed field pinch (RFP). At high current and low density the magnetic topology spontaneously self-organizes in an Ohmical helical symmetry, with the new magnetic axis helically twisting around the geometrical axis of the torus. The separatrix of the island disappears leaving a wide and symmetric thermal structure with large gradients in the electron temperature profile. The new topology still displays an intermittent nature but its overall presence has reached 85% of the current flat-top period. The large gradients in the electron temperature profile appear to be marginal for the destabilization of ion temperature gradient modes on the assumption that ions and electrons have the same gradients. There are indications that higher currents could provide the conditions under which to prove the existence of a true helical equilibrium as the standard RFP configuration.

  5. Study of Saturn electrostatic discharges with high time resolution

    Science.gov (United States)

    Zakharenko, V.; Mylostna, K.; Konovalenko, A.; Kolyadin, V.; Zarka, P.; Griessmeier, J.-M.; Litvinenko, G.; Sidorchuk, M.; Rucker, H.; Fischer, G.; Cecconi, B.; Coffre, A.; Denis, L.; Shevchenko, V.; Nikolaenko, V.

    2013-09-01

    Ground-based observations of SED (Saturn Electrostatic Discharges) with high time resolution are the next stage of extraterrestrial atmospheric processes study. Due to extremely high intensity of Saturn's storm J (2010) [1] we have obtained the records with high signal-to-noise (S/N) ratio with the time resolution of 15 ns. It permitted us to investigate the microsecond structure of lightning and clearly distinguish SED in the presence of local interference in virtue of a dispersive delay of extraterrestrial planetary signals.

  6. Evacuee Compliance Behavior Analysis using High Resolution Demographic Information

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Wei [ORNL; Han, Lee [University of Tennessee, Knoxville (UTK); Liu, Cheng [ORNL; Tuttle, Mark A [ORNL; Bhaduri, Budhendra L [ORNL

    2014-01-01

    The purpose of this study is to examine whether evacuee compliance behavior with route assignments from different resolutions of demographic data would impact the evacuation performance. Most existing evacuation strategies assume that travelers will follow evacuation instructions, while in reality a certain percent of evacuees do not comply with prescribed instructions. In this paper, a comparison study of evacuation assignment based on Traffic Analysis Zones (TAZ) and high resolution LandScan USA Population Cells (LPC) were conducted for the detailed road network representing Alexandria, Virginia. A revised platform for evacuation modeling built on high resolution demographic data and activity-based microscopic traffic simulation is proposed. The results indicate that evacuee compliance behavior affects evacuation efficiency with traditional TAZ assignment, but it does not significantly compromise the efficiency with high resolution LPC assignment. The TAZ assignment also underestimates the real travel time during evacuation, especially for high compliance simulations. This suggests that conventional evacuation studies based on TAZ assignment might not be effective at providing efficient guidance to evacuees. From the high resolution data perspective, traveler compliance behavior is an important factor but it does not impact the system performance significantly. The highlight of evacuee compliance behavior analysis should be emphasized on individual evacuee level route/shelter assignments, rather than the whole system performance.

  7. Design and implementation of spaceborne high resolution infrared touch screen

    Science.gov (United States)

    Li, Tai-guo; Li, Wen-xin; Dong, Yi-peng; Ma, Wen; Xia, Jia-gao

    2015-10-01

    For the consideration of the special application environment of the electronic products used in aerospace and to further more improve the human-computer interaction of the manned aerospace area. The research is based on the design and implementation way of the high resolution spaceborne infrared touch screen on the basis of FPGA and DSP frame structure. Beside the introduction of the whole structure for the high resolution spaceborne infrared touch screen system, this essay also gives the detail information about design of hardware for the high resolution spaceborne infrared touch screen system, FPGA design, GUI design and DSP algorithm design based on Lagrange interpolation. What is more, the easy makes a comprehensive research of the reliability design for the high resolution spaceborne infrared touch screen for the special purpose of it. Besides, the system test is done after installation of spaceborne infrared touch screen. The test result shows that the system is simple and reliable enough, which has a stable running environment and high resolution, which certainly can meet the special requirement of the manned aerospace instrument products.

  8. High resolution imaging using scanning ion conductance microscopy with improved distance feedback control

    Institute of Scientific and Technical Information of China (English)

    Chao Li; Nicholas Johnson; Victor Ostanin; Andrew Shevchuk; Liming Ying; Yuri Korchev; David Klenerman

    2008-01-01

    Microscopy is an essential technique for observation on living cells. There is currently great interest in applying scanning probe microscopy to image-living biological cells in their natural environment at the nanometer scale. Scanning ion conductance microscopy is a new form of scanning probe microscopy, which enables non-contact high-resolution imaging of living biological cells. Based on a scanned nanopipette in physiological buffer, the distance feedback control uses the ion current to control the distance between the pipette tip and the sample surface. However, this feedback control has difficulties over slopes on convoluted cell surfaces, which limits its resolution. In this study, we present an improved form of feedback control that removes the contribution of up to the third-order slope from the ion current signal, hence providing a more accurate signal for controlling the distance. We show that this allows faster and lower noise topographic high-resolution imaging.

  9. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony;

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...

  10. Stars and planets at high spatial and spectral resolution

    NARCIS (Netherlands)

    Albrecht, Simon

    2008-01-01

    The work presented in this thesis involves the development of new instrumental techniques and analysing tools, combining high spectral resolution with high spatial information, with the aim to increase our understanding of the formation and evolution of stars and planets. First, a novel instrumental

  11. Visualization tools for extremely high resolution DEM from the LRO and other orbiter satellites

    Science.gov (United States)

    Montgomery, J.; McDonald, John

    2012-10-01

    Recent space missions have included laser altimetry instrumentation that provides precise high-resolution global topographic data products. These products are critical in analyzing geomorphological surface processes of planets and moons. Although highly valued, the high-resolution data is often overlooked by researchers due to the high level of IT sophistication necessary to use the high-resolution data products, which can be as large as several hundred gigabytes. Researchers have developed software tools to assist in viewing and manipulating data products derived from altimetry data, however current software tools require substantial off-line processing, provide rudimentary visualization or are not suited for viewing the new high-resolution data. We have adapted mVTK, a novel software visualization tool, to work with NASA's recently acquired Lunar Reconnaissance Orbiter data. mVTK is a software visualization package that dynamically creates cylindrical cartographic map projections from gridded high-resolution altimetry data in real-time. The projections are interactive 2D shade relief, false color maps that allow the user to make simple slope and distance measurements on the actual underlying high-resolution data. We have tested mVTK on several laser altimetry data sets including binned gridded record data from NASA's Mars Global Surveyor and Lunar Reconnaissance Orbiter space missions.

  12. Achieving High Resolution Timer Events in Virtualized Environment.

    Directory of Open Access Journals (Sweden)

    Blazej Adamczyk

    Full Text Available Virtual Machine Monitors (VMM have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service. Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  13. High-resolution structure of viruses from random diffraction snapshots

    CERN Document Server

    Hosseinizadeh, A; Dashti, A; Fung, R; D'Souza, R M; Ourmazd, A

    2014-01-01

    The advent of the X-ray Free Electron Laser (XFEL) has made it possible to record diffraction snapshots of biological entities injected into the X-ray beam before the onset of radiation damage. Algorithmic means must then be used to determine the snapshot orientations and thence the three-dimensional structure of the object. Existing Bayesian approaches are limited in reconstruction resolution typically to 1/10 of the object diameter, with the computational expense increasing as the eighth power of the ratio of diameter to resolution. We present an approach capable of exploiting object symmetries to recover three-dimensional structure to high resolution, and thus reconstruct the structure of the satellite tobacco necrosis virus to atomic level. Our approach offers the highest reconstruction resolution for XFEL snapshots to date, and provides a potentially powerful alternative route for analysis of data from crystalline and nanocrystalline objects.

  14. New high resolution synthetic stellar libraries for the Gaia Mission

    CERN Document Server

    Sordo, R; Bouret, J C; Brott, I; Edvardsson, B; Frémat, Y; Heber, U; Josselin, E; Kochukhov, O; Korn, A; Lanzafame, A; Martins, F; Schweitzer, A; Thévenin, F; Zorec, J

    2008-01-01

    High resolution synthetic stellar libraries are of fundamental importance for the preparation of the Gaia Mission. We present new sets of spectral stellar libraries covering two spectral ranges: 300 --1100 nm at 0.1 nm resolution, and 840 -- 890 nm at 0.001 nm resolution. These libraries span a large range in atmospheric parameters, from super-metal-rich to very metal-poor (-5.0 $<$[Fe/H]$<$+1.0), from cool to hot (\\teff=3000--50000 K) stars, including peculiar abundance variations. The spectral resolution, spectral type coverage and number of models represent a substantial improvement over previous libraries used in population synthesis models and in atmospheric analysis.

  15. Subcutaneous Cysticercosis: Role of High Resolution Ultrasound in Diagnosis

    Directory of Open Access Journals (Sweden)

    Sachin Lohra

    2014-02-01

    Full Text Available BACKGROUND: Though the commonest site of extraintestinal infestation with Taenia solium is brain, Subcutaneous cysticercosis is fairly common in asia. The advent of high resolution ultrasound, FNAC, and a heightened clinician awareness of the existence of isolated soft tissue cysticerci has probably supplanted the need for surgical intervention and excision biopsy in asymptomatic subcutaneous cysts, as cysts have high rate of spontaneous resolution. OBJECTIVES: - To observe role of high resolution ultrasound in diagnosis and need of surgical intervention in treatment of subcutaneous cysticercosis. MATERIALS and METHODS: retrospective study of seven cases of extraneural cysticercosis, all involving the subcutaneous tissues or muscles over the arms and torso. Either high resolution ultrasound, FNAC, or excision biopsy, or a combination of these were used to arrive at a diagnosis. All patients were followed up with serial ultrasounds. All patients received oral nitazoxanide for autoinfection. Surgical excision was resorted to in two patients, in whom it was possible to obtain a histopathologic diagnosis. RESULTS: of the seven cases of subcutaneous cysticercosis all have rural background, most of the patients (6 were vegetarian and one was non vegetarian. Age and gender of patient, size and duration of lesion were insignificant in establishing the diagnosis. High resolution ultrasound was highly significant in establishing the diagnosis over FNAC and histopathology. Five of the cases resolved spontaneously and surgical intervention was required only in two cases. INTERPRETATION and CONCLUSIONS: With heightened clinician awareness of the existence of isolated subcutaneous cysticercosis in patients with close animal contact, and the widespread availability of high resolution ultrasound and FNAC, subcutaneous cysticercosis can be diagnosed readily. Surgery can be avoided in the great majority of these patients, as the cysts mostly resolve on their own

  16. High-resolution DEM Effects on Geophysical Flow Models

    Science.gov (United States)

    Williams, M. R.; Bursik, M. I.; Stefanescu, R. E. R.; Patra, A. K.

    2014-12-01

    Geophysical mass flow models are numerical models that approximate pyroclastic flow events and can be used to assess the volcanic hazards certain areas may face. One such model, TITAN2D, approximates granular-flow physics based on a depth-averaged analytical model using inputs of basal and internal friction, material volume at a coordinate point, and a GIS in the form of a digital elevation model (DEM). The volume of modeled material propagates over the DEM in a way that is governed by the slope and curvature of the DEM surface and the basal and internal friction angles. Results from TITAN2D are highly dependent upon the inputs to the model. Here we focus on a single input: the DEM, which can vary in resolution. High resolution DEMs are advantageous in that they contain more surface details than lower-resolution models, presumably allowing modeled flows to propagate in a way more true to the real surface. However, very high resolution DEMs can create undesirable artifacts in the slope and curvature that corrupt flow calculations. With high-resolution DEMs becoming more widely available and preferable for use, determining the point at which high resolution data is less advantageous compared to lower resolution data becomes important. We find that in cases of high resolution, integer-valued DEMs, very high-resolution is detrimental to good model outputs when moderate-to-low (<10-15°) slope angles are involved. At these slope angles, multiple adjacent DEM cell elevation values are equal due to the need for the DEM to approximate the low slope with a limited set of integer values for elevation. The first derivative of the elevation surface thus becomes zero. In these cases, flow propagation is inhibited by these spurious zero-slope conditions. Here we present evidence for this "terracing effect" from 1) a mathematically defined simulated elevation model, to demonstrate the terracing effects of integer valued data, and 2) a real-world DEM where terracing must be

  17. Vehicle Detection and Classification from High Resolution Satellite Images

    Science.gov (United States)

    Abraham, L.; Sasikumar, M.

    2014-11-01

    In the past decades satellite imagery has been used successfully for weather forecasting, geographical and geological applications. Low resolution satellite images are sufficient for these sorts of applications. But the technological developments in the field of satellite imaging provide high resolution sensors which expands its field of application. Thus the High Resolution Satellite Imagery (HRSI) proved to be a suitable alternative to aerial photogrammetric data to provide a new data source for object detection. Since the traffic rates in developing countries are enormously increasing, vehicle detection from satellite data will be a better choice for automating such systems. In this work, a novel technique for vehicle detection from the images obtained from high resolution sensors is proposed. Though we are using high resolution images, vehicles are seen only as tiny spots, difficult to distinguish from the background. But we are able to obtain a detection rate not less than 0.9. Thereafter we classify the detected vehicles into cars and trucks and find the count of them.

  18. High resolution SPM imaging of organic molecules with functionalized tips

    Science.gov (United States)

    Jelínek, Pavel

    2017-08-01

    One of the most remarkable and exciting achievements in the field of scanning probe microscopy (SPM) in the last years is the unprecedented sub-molecular resolution of both atomic and electronic structures of single molecules deposited on solid state surfaces. Despite its youth, the technique has already brought many new possibilities to perform different kinds of measurements, which cannot be accomplished by other techniques. This opens new perspectives in advanced characterization of physical and chemical processes and properties of molecular structures on surfaces. Here, we discuss the history and recent progress of the high resolution imaging with a functionalized probe by means of atomic force microscopy (AFM), scanning tunnelling microscopy (STM) and inelastic electron tunneling spectroscopy (IETS). We describe the mechanisms responsible for the high-resolution AFM, STM and IETS-STM contrast. The complexity of this technique requires new theoretical approaches, where a relaxation of the functionalized probe is considered. We emphasise the similarities of the mechanism driving high-resolution SPM with other imaging methods. We also summarise briefly significant achievements and progress in different branches. Finally we provide brief perspectives and remaining challenges of the further refinement of these high-resolution methods.

  19. High resolution magnetic imaging: MicroSQUID Force Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Hasselbach, K; Ladam, C; Dolocan, V O; Hykel, D; Crozes, T [Institut Neel, CNRS et Universite Joseph Fourier, BP 166, F-38042 Grenoble Cedex 9 (France); Schuster, K [Institut de RadioAstronomie Millimetrique 300 rue de la Piscine, Domaine Universitaire F-38406 Saint Martin d' Heres (France); Mailly, D [Laboratoire de Photonique et de Nanostructures, CNRS, Site Alcatel de Marcoussis Route de Nozay F-91460 Marcoussis (France)], E-mail: klaus.hasselbach@grenoble.cnrs.fr

    2008-02-01

    Magnetic imaging at the micrometer scale with high sensitivity is a challenge difficult to be met. Magnetic force microscopy has a very high spatial resolution but is limited in magnetic resolution. Hall probe microscopy is very powerful but sensor fabrication at the one micron scale is difficult and effects due to discreteness of charge appear in the form of significant 1/f noise. SQUID microscopy is very powerful, having high magnetic resolution, but spatial resolution is usually of the order of 10 {mu}m. The difficulties lay mostly in an efficient way to couple flux to the sensor. The only way to improve spatial resolution is to place the probe close to the very edge of the support, thus maximising coupling and spatial resolution. If there has been found a way to bring close the tip, there must be also found a reliable a way to maintain distance during scanning. We want to present recent improvements on scanning microsquid microscopy: Namely the improved fabrication of microSQUID tips using silicon micro machining and the precise positioning of the micrometer diameter microSQUID loop by electron beam lithography. The microSQUID is a microbridge DC SQUID, with two opposite microbridges. The constrictions are patterned by high-resolution e-beam lithography and have a width of 20 nm and a length of about 100 nm. The distance control during scanning is obtained by integrating the microSQUID sensor with a piezoelectric tuning fork acting as a force sensor allowing to control height and even topographic imaging. The detector is placed in a custom built near field microscope and the sample temperature can be varied between 0.1 Kelvin and 10 K. The microscope is used to study magnetic flux structures in unconventional superconductors and will be used to observe thermal domains in superconducting detectors in the voltage state.

  20. High spatial resolution diffusion tensor imaging and its applications

    CERN Document Server

    Wang, J J

    2002-01-01

    Introduction Magnetic Resonance Imaging is at present the only imaging technique available to measure diffusion of water and metabolites in humans. It provides vital insights to brain connectivity and has proved to be an important tool in diagnosis and therapy planning in many neurological diseases such as brain tumour, ischaemia and multiple sclerosis. This project focuses on the development of a high resolution diffusion tensor imaging technique. In this thesis, the basic theory of diffusion tensor MR Imaging is presented. The technical challenges encountered during development of these techniques will be discussed, with proposed solutions. New sequences with high spatial resolution have been developed and the results are compared with the standard technique more commonly used. Overview The project aims at the development of diffusion tensor imaging techniques with a high spatial resolution. Chapter 2 will describe the basic physics of MRI, the phenomenon of diffusion and the measurement of diffusion by MRI...

  1. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony;

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit hi...... resolution haptic patterns so that they translate naturally to the user’s haptic experience. To solve this question we have developed and tested several visual editors......In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...

  2. A high resolution powder diffractometer using focusing optics

    Indian Academy of Sciences (India)

    V Siruguri; P D Babu; M Gupta; A V Pimpale; P S Goyal

    2008-11-01

    In this paper, we describe the design, construction and performance of a new high resolution neutron powder diffractometer that has been installed at the Dhruva reactor, Trombay, India. The instrument employs novel design concepts like the use of bent, perfect crystal monochromator and open beam geometry, enabling the use of smaller samples. The resolution curve of the instrument was found to have little variation over a wide angular region and a / ∼ 0.3% has been achieved. The instrument provides sample environment of very low temperatures and high magnetic fields using a 7 Tesla cryogen-free superconducting magnet with a VTI having a temperature range of 1.5–320 K. The special sample environment and high resolution make this neutron powder diffractometer a very powerful facility for studying magnetic properties of materials.

  3. Theoretical analysis of high-resolution digital mammography.

    Science.gov (United States)

    Suryanarayanan, Sankararaman; Karellas, Andrew; Vedantham, Srinivasan; Sechopoulos, Ioannis

    2006-06-21

    The performance of a high-resolution charge coupled device-based full-field digital mammography imager was analysed using a mathematical framework based on an adaptation of cascaded linear systems theory described by other investigators. This work has been conducted in order to understand the impact of various design parameters on the physical performance characteristics of the imager. Specifically, the effect of pixel size, scintillator thickness and packing density, x-ray spectra, air kerma, dark current, charge integration time, and pixel fill-factor on the frequency dependent detective quantum efficiency was studied using a charge-coupled device as a reference platform. The imaging system was modelled as a series of physical processes with gain and spatial spreading. For each stage, the signal and noise power spectra were computed and propagated through the imaging chain as inputs to subsequent stages. Good agreement between experimental and theoretical predictions was obtained for various x-ray spectral conditions that were investigated. The modulation transfer function, MTF(f) and detective quantum efficiency DQE(f) characteristics obtained in this study are encouraging and comparable to other digital mammography systems. The results of this study strongly suggest the feasibility of large area scintillator-based digital mammography imagers with pixel sizes below 100 microm.

  4. Small UAV-Acquired, High-resolution, Georeferenced Still Imagery

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Hruska

    2005-09-01

    Currently, small Unmanned Aerial Vehicles (UAVs) are primarily used for capturing and down-linking real-time video. To date, their role as a low-cost airborne platform for capturing high-resolution, georeferenced still imagery has not been fully utilized. On-going work within the Unmanned Vehicle Systems Program at the Idaho National Laboratory (INL) is attempting to exploit this small UAV-acquired, still imagery potential. Initially, a UAV-based still imagery work flow model was developed that includes initial UAV mission planning, sensor selection, UAV/sensor integration, and imagery collection, processing, and analysis. Components to support each stage of the work flow are also being developed. Critical to use of acquired still imagery is the ability to detect changes between images of the same area over time. To enhance the analysts’ change detection ability, a UAV-specific, GIS-based change detection system called SADI or System for Analyzing Differences in Imagery is under development. This paper will discuss the associated challenges and approaches to collecting still imagery with small UAVs. Additionally, specific components of the developed work flow system will be described and graphically illustrated using varied examples of small UAV-acquired still imagery.

  5. Advanced Very High Resolution Radiometer Normalized Difference Vegetation Index Composites

    Science.gov (United States)

    ,

    2005-01-01

    The Advanced Very High Resolution Radiometer (AVHRR) is a broad-band scanner with four to six bands, depending on the model. The AVHRR senses in the visible, near-, middle-, and thermal- infrared portions of the electromagnetic spectrum. This sensor is carried on a series of National Oceanic and Atmospheric Administration (NOAA) Polar Orbiting Environmental Satellites (POES), beginning with the Television InfraRed Observation Satellite (TIROS-N) in 1978. Since 1989, the United States Geological Survey (USGS) Center for Earth Resources Observation and Science (EROS) has been mapping the vegetation condition of the United States and Alaska using satellite information from the AVHRR sensor. The vegetation condition composites, more commonly called greenness maps, are produced every week using the latest information on the growth and condition of the vegetation. One of the most important aspects of USGS greenness mapping is the historical archive of information dating back to 1989. This historical stretch of information has allowed the USGS to determine a 'normal' vegetation condition. As a result, it is possible to compare the current week's vegetation condition with normal vegetation conditions. An above normal condition could indicate wetter or warmer than normal conditions, while a below normal condition could indicate colder or dryer than normal conditions. The interpretation of departure from normal will depend on the season and geography of a region.

  6. Implementation of high-resolution reticle inspection in wafer fabs

    Science.gov (United States)

    Dayal, Aditya; Bergmann, Nathan M.; Sanchez, Peter

    2003-05-01

    Many advanced wafer fabs are currently fabricating devices with 130nm or smaller design rules. To meet the challenges at these sub-wavelength technology nodes, fabs are using a variety of resolution enhancement techniques (RETs) in lithography and exploring new methods of processing, inspecting and requalifying photomasks. The acceleration of the lithography roadmap imposes more stringent requirements on mask qualification and requalification to ensure that device yields are not compromised: mask inspection tools of today need to find smaller defects on reticles against considerably more complicated patterns or tighter critical dimensions (CDs). In this paper we describe the early stages of implementation and proliferation of advanced reticle inspection tools at high volume manufacturing wafer fabs. The fabs run incoming multi-surface contamination inspections on masks sent from the mask shop (Intel Mask Operations, IMO), and follow them up with periodic inspections/review to make sure any new contaminant or damage does not go undetected. When necessary, images of defects are electronically presented to engineers at IMO for review. Reticle requalification with these inspection tools reduces or eliminates the need for print test verification. We describe the tools and procedure used to streamline reticle requalification at the fabs and improve the feedback loop between the fabs and the mask shop.

  7. High-temperature superconducting current leads

    Science.gov (United States)

    Hull, J. R.

    1992-07-01

    The use of high-temperature superconductors (HTSs) for current leads to deliver power to devices at liquid helium temperature is near commercial realization. The use of HTSs in this application has the potential to reduce refrigeration requirements and helium boiloff to values significantly lower than the theoretical best achievable with conventional leads. Considerable advantage is achieved by operating these leads with an intermediate temperature heat sink. The HTS part of the lead can be made from pressed and sintered powder. Powder-in-tube fabrication is also possible, however, the normal metal part of the lead acts as a thermal short and cannot provide much stabilization without increasing the refrigeration required. Lead stability favors designs with low current density. Such leads can be manufactured with today's technology, and lower refrigeration results from the same allowable burnout time. Higher current densities result in lower boiloff for the same lead length, but bumout times can be very short. In comparing experiment to theory, the density of helium vapor needs to be accounted for in calculating the expected boiloff. For very low-loss leads, two-dimensional heat transfer and the state of the dewar near the leads may play a dominant role in lead performance.

  8. Novel techniques in VUV high-resolution spectroscopy

    CERN Document Server

    Ubachs, W; Eikema, K S E; de Oliveira, N; Nahon, L

    2013-01-01

    Novel VUV sources and techniques for VUV spectroscopy are reviewed. Laser-based VUV sources have been developed via non-linear upconversion of laser pulses in the nanosecond (ns), the picosecond (ps), and femtosecond (fs) domain, and are applied in high-resolution gas phase spectroscopic studies. While the ns and ps pulsed laser sources, at Fourier-transform limited bandwidths, are used in wavelength scanning spectroscopy, the fs laser source is used in a two-pulse time delayed mode. In addition a Fourier-transform spectrometer for high resolution gas-phase spectroscopic studies in the VUV is described, exhibiting the multiplex advantage to measure many resonances simultaneously.

  9. High-resolution second harmonic optical coherence tomography

    Science.gov (United States)

    Jiang, Yi; Tomov, Ivan V.; Wang, Yimin; Chen, Zhongping

    2005-04-01

    A high-resolution Second Harmonic Optical Coherence Tomography (SH-OCT) system is demonstrated using a spectrum broadened femtosecond Ti:sapphire laser. An axial resolution of 4.2 μm at the second harmonic wave center wavelength of 400 nm has been achieved. Because the SH-OCT system uses the second harmonic generation signals that strongly depend on the orientation, polarization and local symmetry properties of chiral molecules, this technique provides unique contrast enhancement to conventional optical coherence tomography. The system is applied to image biological tissues like the rat-tail tendon. Images of highly organized collagen fibrils in the rat-tail tendon have been demonstrated.

  10. Progress in high-resolution x-ray holographic microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jacobsen, C.; Kirz, J.; Howells, M.; McQuaid, K.; Rothman, S.; Feder, R.; Sayre, D.

    1987-07-01

    Among the various types of x-ray microscopes that have been demonstrated, the holographic microscope has had the largest gap between promise and performance. The difficulties of fabricating x-ray optical elements have led some to view holography as the most attractive method for obtaining the ultimate in high resolution x-ray micrographs; however, we know of no investigations prior to 1987 that clearly demonstrated submicron resolution in reconstructed images. Previous efforts suffered from problems such as limited resolution and dynamic range in the recording media, low coherent x-ray flux, and aberrations and diffraction limits in visible light reconstruction. We have addressed the recording limitations through the use of an undulator x-ray source and high-resolution photoresist recording media. For improved results in the readout and reconstruction steps, we have employed metal shadowing and transmission electron microscopy, along with numerical reconstruction techniques. We believe that this approach will allow holography to emerge as a practical method of high-resolution x-ray microscopy. 30 refs., 4 figs.

  11. Multi-resolution voxel phantom modeling: a high-resolution eye model for computational dosimetry

    Science.gov (United States)

    Caracappa, Peter F.; Rhodes, Ashley; Fiedler, Derek

    2014-09-01

    Voxel models of the human body are commonly used for simulating radiation dose with a Monte Carlo radiation transport code. Due to memory limitations, the voxel resolution of these computational phantoms is typically too large to accurately represent the dimensions of small features such as the eye. Recently reduced recommended dose limits to the lens of the eye, which is a radiosensitive tissue with a significant concern for cataract formation, has lent increased importance to understanding the dose to this tissue. A high-resolution eye model is constructed using physiological data for the dimensions of radiosensitive tissues, and combined with an existing set of whole-body models to form a multi-resolution voxel phantom, which is used with the MCNPX code to calculate radiation dose from various exposure types. This phantom provides an accurate representation of the radiation transport through the structures of the eye. Two alternate methods of including a high-resolution eye model within an existing whole-body model are developed. The accuracy and performance of each method is compared against existing computational phantoms.

  12. Energy Resolution of Large Area Current-mode Si-PIN Detector

    Institute of Scientific and Technical Information of China (English)

    SU; Dan; ZHANG; Guo-guang; WANG; Guo-bao

    2013-01-01

    Large area current-mode Si-PIN detector is fabricated by adopting planar technology.Diameter are ?20 mm,?50 mm,?60 mm,and thickness is 300μm.Energy resolution and peak position of 226Ra-αparticles are measured in the vacuum chamber.The peak energy of the 226Ra-αparticle is 4 784.4,5 304.5,

  13. High Resolution Simulations of Future Climate in West Africa Using a Variable-Resolution Atmospheric Model

    Science.gov (United States)

    Adegoke, J. O.; Engelbrecht, F.; Vezhapparambu, S.

    2013-12-01

    In previous work demonstrated the application of a var¬iable-resolution global atmospheric model, the conformal-cubic atmospheric model (CCAM), across a wide range of spatial and time scales to investigate the ability of the model to provide realistic simulations of present-day climate and plausible projections of future climate change over sub-Saharan Africa. By applying the model in stretched-grid mode the versatility of the model dynamics, numerical formulation and physical parameterizations to function across a range of length scales over the region of interest, was also explored. We primarily used CCAM to illustrate the capability of the model to function as a flexible downscaling tool at the climate-change time scale. Here we report on additional long term climate projection studies performed by downscaling at much higher resolutions (8 Km) over an area that stretches from just south of Sahara desert to the southern coast of the Niger Delta and into the Gulf of Guinea. To perform these simulations, CCAM was provided with synoptic-scale forcing of atmospheric circulation from 2.5 deg resolution NCEP reanalysis at 6-hourly interval and SSTs from NCEP reanalysis data uses as lower boundary forcing. CCAM 60 Km resolution downscaled to 8 Km (Schmidt factor 24.75) then 8 Km resolution simulation downscaled to 1 Km (Schmidt factor 200) over an area approximately 50 Km x 50 Km in the southern Lake Chad Basin (LCB). Our intent in conducting these high resolution model runs was to obtain a deeper understanding of linkages between the projected future climate and the hydrological processes that control the surface water regime in this part of sub-Saharan Africa.

  14. High resolution spectroscopy in the microwave and far infrared

    Science.gov (United States)

    Pickett, Herbert M.

    1990-01-01

    High resolution rotational spectroscopy has long been central to remote sensing techniques in atmospheric sciences and astronomy. As such, laboratory measurements must supply the required data to make direct interpretation of data for instruments which sense atmospheres using rotational spectra. Spectral measurements in the microwave and far infrared regions are also very powerful tools when combined with infrared measurements for characterizing the rotational structure of vibrational spectra. In the past decade new techniques were developed which have pushed high resolution spectroscopy into the wavelength region between 25 micrometers and 2 mm. Techniques to be described include: (1) harmonic generation of microwave sources, (2) infrared laser difference frequency generation, (3) laser sideband generation, and (4) ultrahigh resolution interferometers.

  15. High resolution map of light pollution over Poland

    Science.gov (United States)

    Netzel, Henryka; Netzel, Paweł

    2016-09-01

    In 1976 Berry introduced a simple mathematical equation to calculate artificial night sky brightness at zenith. In the original model cities, considered as points with given population, are only sources of light emission. In contrary to Berry's model, we assumed that all terrain surface can be a source of light. Emission of light depends on percent of built up area in a given cell. We based on Berry's model. Using field measurements and high-resolution data we obtained the map of night sky brightness over Poland in 100-m resolution. High resolution input data, combined with a very simple model, makes it possible to obtain detailed structures of the night sky brightness without complicating the calculations.

  16. A cloud mask methodology for high resolution remote sensing data combining information from high and medium resolution optical sensors

    Science.gov (United States)

    Sedano, Fernando; Kempeneers, Pieter; Strobl, Peter; Kucera, Jan; Vogt, Peter; Seebach, Lucia; San-Miguel-Ayanz, Jesús

    2011-09-01

    This study presents a novel cloud masking approach for high resolution remote sensing images in the context of land cover mapping. As an advantage to traditional methods, the approach does not rely on thermal bands and it is applicable to images from most high resolution earth observation remote sensing sensors. The methodology couples pixel-based seed identification and object-based region growing. The seed identification stage relies on pixel value comparison between high resolution images and cloud free composites at lower spatial resolution from almost simultaneously acquired dates. The methodology was tested taking SPOT4-HRVIR, SPOT5-HRG and IRS-LISS III as high resolution images and cloud free MODIS composites as reference images. The selected scenes included a wide range of cloud types and surface features. The resulting cloud masks were evaluated through visual comparison. They were also compared with ad-hoc independently generated cloud masks and with the automatic cloud cover assessment algorithm (ACCA). In general the results showed an agreement in detected clouds higher than 95% for clouds larger than 50 ha. The approach produced consistent results identifying and mapping clouds of different type and size over various land surfaces including natural vegetation, agriculture land, built-up areas, water bodies and snow.

  17. High-resolution TFT-LCD for spatial light modulator

    Science.gov (United States)

    Lee, JaeWon; Kim, Yong-Hae; Byun, Chun-Won; Pi, Jae-Eun; Oh, Himchan; Kim, GiHeon; Lee, Myung-Lae; Chu, Hye-Yong; Hwang, Chi-Sun

    2014-06-01

    SLM with very fine pixel pitch is needed for the holographic display system. Among various kinds of SLMs, commercially available high resolution LCoS has been widely used as a spatial light modulator. But the size of commercially available LCoS SLM is limited because the manufacturing technology of LCoS is based on the semiconductor process developed on small size Si wafer. Recently very high resolution flat panel display panel (~500ppi) was developed as a "retina display". Until now, the pixel pitch of flat panel display is several times larger than the pixel pitch of LCoS. But considering the possibility of shrink down the pixel pitch with advanced lithographic tools, the application of flat panel display will make it possible to build a SLM with high spatial bandwidth product. We simulated High resolution TFT-LCD panel on glass substrate using oxide semiconductor TFT with pixel pitch of 20um. And we considered phase modulation behavior of LC(ECB) mode. The TFT-LCD panel is reflective type with 4-metal structure with organic planarization layers. The technical challenge for high resolution large area SLM will be discussed with very fine pixel.

  18. High resolution multiplexed functional imaging in live embryos (Conference Presentation)

    Science.gov (United States)

    Xu, Dongli; Zhou, Weibin; Peng, Leilei

    2017-02-01

    Fourier multiplexed fluorescence lifetime imaging (FmFLIM) scanning laser optical tomography (FmFLIM-SLOT) combines FmFLIM and Scanning laser optical tomography (SLOT) to perform multiplexed 3D FLIM imaging of live embryos. The system had demonstrate multiplexed functional imaging of zebrafish embryos genetically express Foster Resonant Energy Transfer (FRET) sensors. However, previous system has a 20 micron resolution because the focused Gaussian beam diverges quickly from the focused plane, makes it difficult to achieve high resolution imaging over a long projection depth. Here, we present a high-resolution FmFLIM-SLOT system with achromatic Bessel beam, which achieves 3 micron resolution in 3D deep tissue imaging. In Bessel-FmFLIM-SLOT, multiple laser excitation lines are firstly intensity modulated by a Michelson interferometer with a spinning polygon mirror optical delay line, which enables Fourier multiplexed multi-channel lifetime measurements. Then, a spatial light modulator and a prism are used to transform the modulated Gaussian laser beam to an achromatic Bessel beam. The achromatic Bessel beam scans across the whole specimen with equal angular intervals as sample rotated. After tomography reconstruction and the frequency domain lifetime analysis method, both the 3D intensity and lifetime image of multiple excitation-emission can be obtained. Using Bessel-FmFLIM-SLOT system, we performed cellular-resolution FLIM tomography imaging of live zebrafish embryo. Genetically expressed FRET sensors in these embryo will allow non-invasive observation of multiple biochemical processes in vivo.

  19. The AX-PET project Demonstration of a high resolution axial 3D PET

    CERN Document Server

    Bolle, E; Casella, C; Chesi, E; Clinthorne, N; Cochran, E; De Leo, R; Dissertori, G; Djambazov, G; Fanti, V; Honscheid, K; Huh, S; Johnson, I; Joram, C; Kagan, H; Lustermann, W; Meddi, F; Nappi, E; Nessi-Tedaldi, F; Oliver, J F; Pauss, P; Rafecas, M; Renker, D; Rudge, A; Schinzel, D; Schneider, T; Seguinot, J; Smith, S; Solevi, P; Stapnes, S; Weilhammer, P

    2010-01-01

    The AX-PET is a new geometrical concept for a high resolution 3D PET scanner, based on matrices of axially oriented LYSO crystals interleaved by stacks of WLS, both individually read out by G-APDs. A PET demonstrator, based on two detector modules used in coincidence, is currently under construction.

  20. Observation of Tropical Rain Forest Trees by Airborne High-Resolution Interferometric Radar

    NARCIS (Netherlands)

    Hoekman, D.H.; Varekamp, C.

    2001-01-01

    The Indonesian Radar Experiment (INDREX) Campaign was executed in Indonesia to study the potential of high-resolution interferometric airborne radar in support of sustainable tropical forest management. Severe cloud cover limits the use of aerial photography, which is currently applied on a routine

  1. High-resolution haplotype block structure in the cattle genome

    Directory of Open Access Journals (Sweden)

    Choi Jungwoo

    2009-04-01

    Full Text Available Abstract Background The Bovine HapMap Consortium has generated assay panels to genotype ~30,000 single nucleotide polymorphisms (SNPs from 501 animals sampled from 19 worldwide taurine and indicine breeds, plus two outgroup species (Anoa and Water Buffalo. Within the larger set of SNPs we targeted 101 high density regions spanning up to 7.6 Mb with an average density of approximately one SNP per 4 kb, and characterized the linkage disequilibrium (LD and haplotype block structure within individual breeds and groups of breeds in relation to their geographic origin and use. Results From the 101 targeted high-density regions on bovine chromosomes 6, 14, and 25, between 57 and 95% of the SNPs were informative in the individual breeds. The regions of high LD extend up to ~100 kb and the size of haplotype blocks ranges between 30 bases and 75 kb (10.3 kb average. On the scale from 1–100 kb the extent of LD and haplotype block structure in cattle has high similarity to humans. The estimation of effective population sizes over the previous 10,000 generations conforms to two main events in cattle history: the initiation of cattle domestication (~12,000 years ago, and the intensification of population isolation and current population bottleneck that breeds have experienced worldwide within the last ~700 years. Haplotype block density correlation, block boundary discordances, and haplotype sharing analyses were consistent in revealing unexpected similarities between some beef and dairy breeds, making them non-differentiable. Clustering techniques permitted grouping of breeds into different clades given their similarities and dissimilarities in genetic structure. Conclusion This work presents the first high-resolution analysis of haplotype block structure in worldwide cattle samples. Several novel results were obtained. First, cattle and human share a high similarity in LD and haplotype block structure on the scale of 1–100 kb. Second, unexpected

  2. Immersion Gratings for Infrared High-resolution Spectroscopy

    Science.gov (United States)

    Sarugaku, Yuki; Ikeda, Yuji; Kobayashi, Naoto; Kaji, Sayumi; Sukegawa, Takashi; Sugiyama, Shigeru; Nakagawa, Takao; Arasaki, Takayuki; Kondo, Sohei; Nakanishi, Kenshi; Yasui, Chikako; Kawakita, Hideyo

    2016-10-01

    High-resolution spectroscopy in the infrared wavelength range is essential for observations of minor isotopologues, such as HDO for water, and prebiotic organic molecules like hydrocarbons/P-bearing molecules because numerous vibrational molecular bands (including non-polar molecules) are located in this wavelength range. High spectral resolution enables us to detect weak lines without spectral line confusion. This technique has been widely used in planetary sciences, e.g., cometary coma (H2O, CO, and organic molecules), the martian atmosphere (CH4, CO2, H2O and HDO), and the upper atmosphere of gas giants (H3+ and organic molecules such as C2H6). Spectrographs with higher resolution (and higher sensitivity) still have a potential to provide a plenty of findings. However, because the size of spectrographs scales with the spectral resolution, it is difficult to realize it.Immersion grating (IG), which is a diffraction grating wherein the diffraction surface is immersed in a material with a high refractive index (n > 2), provides n times higher spectral resolution compared to a reflective grating of the same size. Because IG reduces the size of spectrograph to 1/n compared to the spectrograph with the same spectral resolution using a conventional reflective grating, it is widely acknowledged as a key optical device to realize compact spectrographs with high spectral resolution.Recently, we succeeded in fabricating a CdZnTe immersion grating with the theoretically predicted diffraction efficiency by machining process using an ultrahigh-precision five-axis processing machine developed by Canon Inc. Using the same technique, we completed a practical germanium (Ge) immersion grating with both a reflection coating on the grating surface and the an AR coating on the entrance surface. It is noteworthy that the wide wavelength range from 2 to 20 um can be covered by the two immersion gratings.In this paper, we present the performances and the applications of the immersion

  3. A DVD Spectroscope: A Simple, High-Resolution Classroom Spectroscope

    Science.gov (United States)

    Wakabayashi, Fumitaka; Hamada, Kiyohito

    2006-01-01

    Digital versatile disks (DVDs) have successfully made up an inexpensive but high-resolution spectroscope suitable for classroom experiments that can easily be made with common material and gives clear and fine spectra of various light sources and colored material. The observed spectra can be photographed with a digital camera, and such images can…

  4. High-resolution kinetic energy distributions via doppler shift measurements

    Science.gov (United States)

    Xu, Z.; Koplitz, B.; Buelow, S.; Baugh, D.; Wittig, C.

    1986-07-01

    In photolysis/probe experiments using pulsed sources, time delay produces both spatial and directional bias in the fragment distributions, thus enabling well-resolved kinetic energy distributions to be obtained from Doppler shift measurements. Data are presented for H-atoms detected using two-photon ionization, and high S/N and laser-limited kinetic energy resolution are demonstrated.

  5. High resolution ultraviolet imaging spectrometer for latent image analysis.

    Science.gov (United States)

    Lyu, Hang; Liao, Ningfang; Li, Hongsong; Wu, Wenmin

    2016-03-21

    In this work, we present a close-range ultraviolet imaging spectrometer with high spatial resolution, and reasonably high spectral resolution. As the transmissive optical components cause chromatic aberration in the ultraviolet (UV) spectral range, an all-reflective imaging scheme is introduced to promote the image quality. The proposed instrument consists of an oscillating mirror, a Cassegrain objective, a Michelson structure, an Offner relay, and a UV enhanced CCD. The finished spectrometer has a spatial resolution of 29.30μm on the target plane; the spectral scope covers both near and middle UV band; and can obtain approximately 100 wavelength samples over the range of 240~370nm. The control computer coordinates all the components of the instrument and enables capturing a series of images, which can be reconstructed into an interferogram datacube. The datacube can be converted into a spectrum datacube, which contains spectral information of each pixel with many wavelength samples. A spectral calibration is carried out by using a high pressure mercury discharge lamp. A test run demonstrated that this interferometric configuration can obtain high resolution spectrum datacube. The pattern recognition algorithm is introduced to analyze the datacube and distinguish the latent traces from the base materials. This design is particularly good at identifying the latent traces in the application field of forensic imaging.

  6. A Large Scale, High Resolution Agent-Based Insurgency Model

    Science.gov (United States)

    2013-09-30

    2007). HSCB Models can be employed for simulating mission scenarios, determining optimal strategies for disrupting terrorist networks, or training and...High Resolution Agent-Based Insurgency Model ∑ = ⎜ ⎜ ⎝ ⎛ − −− = desired 1 move,desired, desired,,desired, desired,, N j ij jmoveij moveiD rp prp

  7. Workshop on high-resolution, large-acceptance spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Zeidman, B. (ed.)

    1981-01-01

    The purpose of the Workshop on High-Resolution, Large-Acceptance Spectrometers was to provide a means for exchange of information among those actively engaged in the design and construction of these new spectrometers. Thirty-seven papers were prepared for the data base.

  8. Remote parallel rendering for high-resolution tiled display walls

    KAUST Repository

    Nachbaur, Daniel

    2014-11-01

    © 2014 IEEE. We present a complete, robust and simple to use hardware and software stack delivering remote parallel rendering of complex geometrical and volumetric models to high resolution tiled display walls in a production environment. We describe the setup and configuration, present preliminary benchmarks showing interactive framerates, and describe our contributions for a seamless integration of all the software components.

  9. High resolution STEM of quantum dots and quantum wires

    DEFF Research Database (Denmark)

    Kadkhodazadeh, Shima

    2013-01-01

    This article reviews the application of high resolution scanning transmission electron microscopy (STEM) to semiconductor quantum dots (QDs) and quantum wires (QWRs). Different imaging and analytical techniques in STEM are introduced and key examples of their application to QDs and QWRs...

  10. Structure Identification in High-Resolution Transmission Electron Microscopic Images

    DEFF Research Database (Denmark)

    Vestergaard, Jacob Schack; Kling, Jens; Dahl, Anders Bjorholm

    2014-01-01

    A connection between microscopic structure and macroscopic properties is expected for almost all material systems. High-resolution transmission electron microscopy is a technique offering insight into the atomic structure, but the analysis of large image series can be time consuming. The present ...

  11. Signal Processing for High Resolution FMCW SAR and Moving Target

    NARCIS (Netherlands)

    Meta, A.; Hoogeboom, P.

    2005-01-01

    The combination of Frequency Modulated ContinuousWave (FMCW) technology and Synthetic Aperture Radar (SAR) leads to lightweight, cost-effective imaging sensors of high resolution. In FMCW SAR applications the conventional stop-and-go approximation used in pulse radar algorithms cannot be considered

  12. High Resolution Digital Imaging of Paintings: The Vasari Project.

    Science.gov (United States)

    Martinez, Kirk

    1991-01-01

    Describes VASARI (the Visual Art System for Archiving and Retrieval of Images), a project funded by the European Community to show the feasibility of high resolution colormetric imaging directly from paintings. The hardware and software used in the system are explained, storage on optical disks is described, and initial results are reported. (five…

  13. Ultra-high-resolution small-animal SPECT imaging

    NARCIS (Netherlands)

    Have, F. van der

    2007-01-01

    The main subject of this thesis is the development of the first two in a series of dedicated ultra-high resolution Single Photon Emission Computed Tomography (SPECT) systems (U-SPECT-I and II) for the imaging of distributions of radio-isotope labeled tracers in small laboratory animals such as mice

  14. HIGH RESOLUTION RESISTIVITY LEAK DETECTION DATA PROCESSING & EVALUATION MEHTODS & REQUIREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    SCHOFIELD JS

    2007-10-04

    This document has two purposes: {sm_bullet} Describe how data generated by High Resolution REsistivity (HRR) leak detection (LD) systems deployed during single-shell tank (SST) waste retrieval operations are processed and evaluated. {sm_bullet} Provide the basic review requirements for HRR data when Hrr is deployed as a leak detection method during SST waste retrievals.

  15. High resolution ultrasonography in isolated soft tissue and intramuscular cysticercosis

    Directory of Open Access Journals (Sweden)

    Gaurav Sharma

    2016-01-01

    Conclusions: With the advent of high resolution ultrasonography and increased clinical awareness of the isolated soft tissue-intramuscular cysticercosis especially in endemic zone, a more conservative non-invasive approach can be applied both in diagnosis and treatment of these isolated cases of cysticercosis. [Int J Res Med Sci 2016; 4(1.000: 42-46

  16. Development of high accuracy and resolution geoid and gravity maps

    Science.gov (United States)

    Gaposchkin, E. M.

    1986-01-01

    Precision satellite to satellite tracking can be used to obtain high precision and resolution maps of the geoid. A method is demonstrated to use data in a limited region to map the geopotential at the satellite altitude. An inverse method is used to downward continue the potential to the Earth surface. The method is designed for both satellites in the same low orbit.

  17. Systematic high-resolution assessment of global hydropower potential

    NARCIS (Netherlands)

    Hoes, Olivier A C; Meijer, Lourens J J; Van Der Ent, Ruud J.; Van De Giesen, Nick C.

    2017-01-01

    Population growth, increasing energy demand and the depletion of fossil fuel reserves necessitate a search for sustainable alternatives for electricity generation. Hydropower could replace a large part of the contribution of gas and oil to the present energy mix. However, previous high-resolution

  18. High-resolution radio imaging of young supernovae

    CERN Document Server

    Pérez-Torres, M A; Alberdi, A; Ros, E; Guirado, J C; Lara, L; Mantovani, F; Stockdale, C J; Weiler, K W; Diamond, P J; Van Dyk, S D; Lundqvist, P; Panagia, N; Shapiro, I I; Sramek, R

    2004-01-01

    The high resolution obtained through the use of VLBI gives an unique opportunity to directly observe the interaction of an expanding radio supernova with its surrounding medium. We present here results from our VLBI observations of the young supernovae SN 1979C, SN 1986J, and SN 2001gd.

  19. High energy resolution off-resonant X-ray spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Wojciech, Blachucki [Univ. of Fribourg (Switzerland). Dept. of Physics

    2015-10-16

    This work treats of the high energy resolution off-resonant X-ray spectroscopy (HEROS) method of determining the density of unoccupied electronic states in the vicinity of the absorption edge. HEROS is an alternative to the existing X-ray absorption spectroscopy (XAS) methods and opens the way for new studies not achievable before.

  20. High-resolution palaeoclimatology of the last millennium

    DEFF Research Database (Denmark)

    Vinther, Bo Møllesøe; Jones, P.D.; Briffa, K.R.

    2009-01-01

    Palaeoclimatology • high-resolution • last millennium • tree rings • dendroclimatology • chronology • uncertainty • corals • ice-cores • speleothems • documentary evidence • instrumental records • varves • borehole temperature • marine sediments • composite plus scaling • CPS • climate field...

  1. Resolution of RNA using high-performance liquid chromatography

    NARCIS (Netherlands)

    Mclaughlin, L.W.; Bischoff, Rainer

    1987-01-01

    High-performance liquid chromatographic techniques can be very effective for the resolution and isolation of nucleic acids. The characteristic ionic (phosphodiesters) and hydrophobic (nucleobases) properties of RNAs can be exploited for their separation. In this respect anion-exchange and reversed-p

  2. Current trends in high temperature design

    Energy Technology Data Exchange (ETDEWEB)

    Marriott, D.L. (Illinois Univ., Urbana, IL (United States). Dept. of Mechanical Engineering)

    1992-01-01

    A review of high temperature design guidelines has been carried out in preparation for designing a solar storage module for the Freedom Spacelab. Three major guidelines, N47, R5 and RCC-MR form the basis of the survey. The main issues with current, mature design in the power industry appear to be adequately covered by these guidelines. A significant finding is that long established models of material damage have survived the test of time very well. A new design regime referred to as Very High Temperature Design (VHTD) is identified. The characteristics of this regime are changing material properties which require some changes in philosophy in drafting of future codes, particularly in regard to definitions of yield strengths and other design allowables. Finally, there is some discussion of the more general use of the stress/strain plane, e.g. isochronous curves, for representation of very complex material constitutive behaviour. A concept called the 'Relaxation Locus', which summarizes essential local constrained component behavior, is introduced and its application to high temperature design problems is discussed briefly. (author).

  3. Five Micron High Resolution MALDI Mass Spectrometry Imaging with Simple, Interchangeable, Multi-Resolution Optical System

    Science.gov (United States)

    Feenstra, Adam D.; Dueñas, Maria Emilia; Lee, Young Jin

    2017-01-01

    High-spatial resolution mass spectrometry imaging (MSI) is crucial for the mapping of chemical distributions at the cellular and subcellular level. In this work, we improved our previous laser optical system for matrix-assisted laser desorption ionization (MALDI)-MSI, from 9 μm practical laser spot size to a practical laser spot size of 4 μm, thereby allowing for 5 μm resolution imaging without oversampling. This is accomplished through a combination of spatial filtering, beam expansion, and reduction of the final focal length. Most importantly, the new laser optics system allows for simple modification of the spot size solely through the interchanging of the beam expander component. Using 10×, 5×, and no beam expander, we could routinely change between 4, 7, and 45 μm laser spot size, in less than 5 min. We applied this multi-resolution MALDI-MSI system to a single maize root tissue section with three different spatial resolutions of 5, 10, and 50 μm and compared the differences in imaging quality and signal sensitivity. We also demonstrated the difference in depth of focus between the optical systems with 10× and 5× beam expanders.

  4. Copper Decoration of Carbon Nanotubes and High Resolution Electron Microscopy

    Science.gov (United States)

    Probst, Camille

    size smaller than the size of the observed object (sample features) does not improve the spatial resolution. In addition, the effects of the accelerating voltage, the current intensity and the sample geometry and composition were analysed.

  5. Topography improvements in MEMS DMs for high-contrast, high-resolution imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will develop and demonstrate an innovative microfabrication process to substantially improve the surface quality achievable in high-resolution...

  6. High resolution cross strip anodes for photon counting detectors

    Science.gov (United States)

    Siegmund, O. H. W.; Tremsin, A. S.; Vallerga, J. V.; Abiad, R.; Hull, J.

    2003-05-01

    A new photon counting, imaging readout for microchannel plate sensors, the cross strip (XS) anode, has been investigated. Charge centroiding of signals detected on two orthogonal layers of sense strip sets are used to derive photon locations. The XS anode spatial resolution (<3 μm FWHM) exceeds the spatial resolution of most direct charge sensing anodes, and does so at low gain (<2×10 6). The image linearity and fidelity are high enough to resolve and map 7 μm MCP pores, offering new possibilities for astronomical and other applications.

  7. High resolution atomic force microscopy of double-stranded RNA

    Science.gov (United States)

    Ares, Pablo; Fuentes-Perez, Maria Eugenia; Herrero-Galán, Elías; Valpuesta, José M.; Gil, Adriana; Gomez-Herrero, Julio; Moreno-Herrero, Fernando

    2016-06-01

    Double-stranded (ds) RNA mediates the suppression of specific gene expression, it is the genetic material of a number of viruses, and a key activator of the innate immune response against viral infections. The ever increasing list of roles played by dsRNA in the cell and its potential biotechnological applications over the last decade has raised an interest for the characterization of its mechanical properties and structure, and that includes approaches using Atomic Force Microscopy (AFM) and other single-molecule techniques. Recent reports have resolved the structure of dsDNA with AFM at unprecedented resolution. However, an equivalent study with dsRNA is still lacking. Here, we have visualized the double helix of dsRNA under near-physiological conditions and at sufficient resolution to resolve the A-form sub-helical pitch periodicity. We have employed different high-sensitive force-detection methods and obtained images with similar spatial resolution. Therefore, we show here that the limiting factors for high-resolution AFM imaging of soft materials in liquid medium are, rather than the imaging mode, the force between the tip and the sample and the sharpness of the tip apex.Double-stranded (ds) RNA mediates the suppression of specific gene expression, it is the genetic material of a number of viruses, and a key activator of the innate immune response against viral infections. The ever increasing list of roles played by dsRNA in the cell and its potential biotechnological applications over the last decade has raised an interest for the characterization of its mechanical properties and structure, and that includes approaches using Atomic Force Microscopy (AFM) and other single-molecule techniques. Recent reports have resolved the structure of dsDNA with AFM at unprecedented resolution. However, an equivalent study with dsRNA is still lacking. Here, we have visualized the double helix of dsRNA under near-physiological conditions and at sufficient resolution to

  8. Design for a focusing high-resolution neutron crystal diffractometer

    CERN Document Server

    Ionita, I; Popovici, M; Popa, N C

    1999-01-01

    A new concept of high-resolution focusing configuration begins to be accepted as an alternative solution to the existing conventional configurations. Among the earliest work performed in this direction is that performed at the Institute for Nuclear Research, Pitesti. These results are presented below. The experimentally determined resolution properties for two focusing configurations obtained at TRIGA reactor Pitesti and at VVRS reactor Bucharest are given in order to be compared with those obtained for the conventional ones. The principles to get focusing in crystal neutron diffractometry are presented. The main characteristics for a focusing instrument are given. (author)

  9. High resolution full-spectrum water Raman lidar

    Institute of Scientific and Technical Information of China (English)

    LIU FuChao; YI Fan; JIA JingYu; ZHANG YunPeng; ZHANG ShaoDong; YU ChangMing; TAN Ying

    2012-01-01

    Knowledge of the temporal-spatial distribution of water content in atmosphere and water phase change in cloud is important for atmospheric study.For this purpose,we have developed a high resolution full-spectrum water Raman lidar that can collect Raman signals from ice,water droplets and water vapor simultaneously.A double-grating polychromator and a 32-channel photomultiplier-tube detector are used to obtain a spectral resolution of ~0.19 nm in the full Raman spectrum range of water.Preliminary observations present the water Raman spectrum characteristics of both the mixed-phase cloud and humid air under cloudless condition.

  10. High resolution polar Kerr magnetometer for nanomagnetism and nanospintronics.

    Science.gov (United States)

    Cormier, M; Ferré, J; Mougin, A; Cromières, J-P; Klein, V

    2008-03-01

    A new high resolution polar magneto-optical (MO) Kerr magnetometer, devoted to the study of nanometer sized elements with perpendicular magnetic anisotropy, is described. The unique performances of this setup in terms of sensitivity (1.2x10(-15) emu), stability (lateral drift +/-35 nm over 3 h), and resolution (laser spot full width at half maximum down to 470 nm) are demonstrated, and illustrated by Kerr hysteresis loop measurements on a unique ultrathin magnetic nanodot, and over small segments of ultranarrow magnetic tracks. Large scanning MO Kerr microscopy images were also obtained with the same performances.

  11. Multiplatform observations enabling albedo retrievals with high temporal resolution

    Science.gov (United States)

    Riihelä, Aku; Manninen, Terhikki; Key, Jeffrey; Sun, Qingsong; Sütterlin, Melanie; Lattanzio, Alessio; Schaaf, Crystal

    2017-04-01

    In this paper we show that combining observations from different polar orbiting satellite families (such as AVHRR and MODIS) is physically justifiable and technically feasible. Our proposed approach will lead to surface albedo retrievals at higher temporal resolution than the state of the art, with comparable or better accuracy. This study is carried out in the World Meteorological Organization (WMO) Sustained and coordinated processing of Environmental Satellite data for Climate Monitoring (SCOPE-CM) project SCM-02 (http://www.scope-cm.org/projects/scm-02/). Following a spectral homogenization of the Top-of-Atmosphere reflectances of bands 1 & 2 from AVHRR and MODIS, both observation datasets are atmospherically corrected with a coherent atmospheric profile and algorithm. The resulting surface reflectances are then fed into an inversion of the RossThick-LiSparse-Reciprocal surface bidirectional reflectance distribution function (BRDF) model. The results of the inversion (BRDF kernels) may then be integrated to estimate various surface albedo quantities. A key principle here is that the larger number of valid surface observations with multiple satellites allows us to invert the BRDF coefficients within a shorter time span, enabling the monitoring of relatively rapid surface phenomena such as snowmelt. The proposed multiplatform approach is expected to bring benefits in particular to the observation of the albedo of the polar regions, where persistent cloudiness and long atmospheric path lengths present challenges to satellite-based retrievals. Following a similar logic, the retrievals over tropical regions with high cloudiness should also benefit from the method. We present results from a demonstrator dataset of a global combined AVHRR-GAC and MODIS dataset covering the year 2010. The retrieved surface albedo is compared against quality-monitored in situ albedo observations from the Baseline Surface Radiation Network (BSRN). Additionally, the combined retrieval

  12. High-resolution axial MR imaging of tibial stress injuries

    Directory of Open Access Journals (Sweden)

    Mammoto Takeo

    2012-05-01

    Full Text Available Abstract Purpose To evaluate the relative involvement of tibial stress injuries using high-resolution axial MR imaging and the correlation with MR and radiographic images. Methods A total of 33 patients with exercise-induced tibial pain were evaluated. All patients underwent radiograph and high-resolution axial MR imaging. Radiographs were taken at initial presentation and 4 weeks later. High-resolution MR axial images were obtained using a microscopy surface coil with 60 × 60 mm field of view on a 1.5T MR unit. All images were evaluated for abnormal signals of the periosteum, cortex and bone marrow. Results Nineteen patients showed no periosteal reaction at initial and follow-up radiographs. MR imaging showed abnormal signals in the periosteal tissue and partially abnormal signals in the bone marrow. In 7 patients, periosteal reaction was not seen at initial radiograph, but was detected at follow-up radiograph. MR imaging showed abnormal signals in the periosteal tissue and entire bone marrow. Abnormal signals in the cortex were found in 6 patients. The remaining 7 showed periosteal reactions at initial radiograph. MR imaging showed abnormal signals in the periosteal tissue in 6 patients. Abnormal signals were seen in the partial and entire bone marrow in 4 and 3 patients, respectively. Conclusions Bone marrow abnormalities in high-resolution axial MR imaging were related to periosteal reactions at follow-up radiograph. Bone marrow abnormalities might predict later periosteal reactions, suggesting shin splints or stress fractures. High-resolution axial MR imaging is useful in early discrimination of tibial stress injuries.

  13. High resolution tomography of objects with access to a single side

    Energy Technology Data Exchange (ETDEWEB)

    Thoe, R.S.

    1993-03-24

    The author is developing a technique which will enable one to obtain high-contrast, high-spatial resolution, three-dimensional images in opaque objects. The only constraint will be the radiation source and detector(s) will be located on the same side of the object. The goal is to obtain images with a spatial resolution of {approximately}1 mm at depths of 10 mm and {approximately}3 mm at depths of 30 mm in materials of moderate density (brass, steel, etc.). The author`s technique uses a highly-collimated beam of monochromatic gamma rays and a slit collimated high-resolution, high-efficiency, coaxial germanium spectrometer. If the geometry is well known, the spectrum of Compton scattered radiation can be used to map out the density as a function of depth. By scanning the object in two dimensions, a full three-dimensional image of the electron density can be reconstructed. The resolution is dependent on the incident beam collimation and the energy resolution of the spectrometer. For his system, the author anticipates a resolution of about 1 mm{sup 3}. The apparatus, reconstruction algorithms and current data verifying his predictions are presented here. Also included are the details on how the system can be modified to increase the efficiency by over two orders of magnitude. This system will have several advantages over conventional transmission radiographic and tomographic systems: (1) It requires the use of a high specific intensity isotopic source of modest activity (< 100 mCi). (2) It requires only a single high-resolution spectrometer used in conjunction with an array of low-resolution detectors (all readily available). (3) It allows for the recording of three-dimensional images of object even though both detector and source are located on the same side of the object.

  14. Achromatic beam transport of High Current Injector

    Science.gov (United States)

    Kumar, Sarvesh; Mandal, A.

    2016-02-01

    The high current injector (HCI) provides intense ion beams of high charge state using a high temperature superconducting ECR ion source. The ion beam is accelerated upto a final energy of 1.8 MeV/u due to an electrostatic potential, a radio frequency quadrupole (RFQ) and a drift tube linac (DTL). The ion beam has to be transported to superconducting LINAC which is around 50 m away from DTL. This section is termed as high energy beam transport section (HEBT) and is used to match the beam both in transverse and longitudinal phase space to the entrance of LINAC. The HEBT section is made up of four 90 deg. achromatic bends and interconnecting magnetic quadrupole triplets. Two RF bunchers have been used for longitudinal phase matching to the LINAC. The ion optical design of HEBT section has been simulated using different beam dynamics codes like TRACEWIN, GICOSY and TRACE 3D. The field computation code OPERA 3D has been utilized for hardware design of all the magnets. All the dipole and quadrupole magnets have been field mapped and their test results such as edge angles measurements, homogeneity and harmonic analysis etc. are reported. The whole design of HEBT section has been performed such that the most of the beam optical components share same hardware design and there is ample space for beam diagnostics as per geometry of the building. Many combination of achromatic bends have been simulated to transport the beam in HEBT section but finally the four 90 deg. achromatic bend configuration is found to be the best satisfying all the geometrical constraints with simplified beam tuning process in real time.

  15. Spatial resolution effects on the assessment of evapotranspiration in olive orchards using high resolution thermal imagery

    Science.gov (United States)

    Santos, Cristina; Zarco-Tejada, Pablo J.; Lorite, Ignacio J.; Allen, Richard G.

    2013-04-01

    The use of remote sensing techniques for estimating surface energy balance and water consumption has significantly improved the characterization of the agricultural systems by determining accurate information about crop evapotranspiration and stress, mainly for extensive crops. However the use of these methodologies for woody crops has been low due to the difficulty in the accurate characterization of these crops, mainly caused by a coarse resolution of the imagery provided by the most widely used satellites (such as Landsat 5 and 7). The coarse spatial resolution provided by these satellite sensors aggregates into a single pixel the tree crown, sunlit and shaded soil components. These surfaces can each exhibit huge differences in temperature, albedo and vegetation indexes calculated in the visible, near infrared and short-wave infrared regions. Recent studies have found that the use of energy balance approaches can provide useful results for non-homogeneous crops (Santos et al., 2012) but detailed analysis is required to determine the effect of the spatial resolution and the aggregation of the scene components in these heterogeneous canopies. In this study a comparison between different spatial resolutions has been conducted using images from Landsat 7 (with thermal resolution of 60m) and from an airborne thermal (with resolution of 80 cm) flown over olive orchards at different dates coincident with the Landsat overpass. The high resolution thermal imagery was resampled at different scales to generate images with spatial resolution ranging from 0.8 m up to 120m (thermal resolution for Landsat 5 images). The selection of the study area was made to avoid those areas with missing Landsat 7 data caused by SLC-off gaps. The selected area has a total area of around 2500 ha and is located in Southern Spain, in the province of Malaga. The selected area is mainly cultivated with olive orchards with different crop practices (rainfed, irrigated, high density, young and adult

  16. Practical Considerations for High Spatial and Temporal Resolution Dynamic Transmission Electron Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, M; Boyden, K; Browning, N D; Campbell, G H; Colvin, J D; DeHope, B; Frank, A M; Gibson, D J; Hartemann, F; Kim, J S; King, W E; LaGrange, T B; Pyke, B J; Reed, B W; Shuttlesworth, R M; Stuart, B C; Torralva, B R

    2006-05-01

    Although recent years have seen significant advances in the spatial resolution possible in the transmission electron microscope (TEM), the temporal resolution of most microscopes is limited to video rate at best. This lack of temporal resolution means that our understanding of dynamic processes in materials is extremely limited. High temporal resolution in the TEM can be achieved, however, by replacing the normal thermionic or field emission source with a photoemission source. In this case the temporal resolution is limited only by the ability to create a short pulse of photoexcited electrons in the source, and this can be as short as a few femtoseconds. The operation of the photo-emission source and the control of the subsequent pulse of electrons (containing as many as 5 x 10{sup 7} electrons) create significant challenges for a standard microscope column that is designed to operate with a single electron in the column at any one time. In this paper, the generation and control of electron pulses in the TEM to obtain a temporal resolution <10{sup -6} s will be described and the effect of the pulse duration and current density on the spatial resolution of the instrument will be examined. The potential of these levels of temporal and spatial resolution for the study of dynamic materials processes will also be discussed.

  17. SAGA GIS based processing of spatial high resolution temperature data

    Energy Technology Data Exchange (ETDEWEB)

    Gerlitz, Lars; Bechtel, Benjamin; Kawohl, Tobias; Boehner, Juergen [Hamburg Univ. (Germany). Inst. of Geography; Zaksek, Klemen [Hamburg Univ. (Germany). Inst. of Geophysics

    2013-07-01

    Many climate change impact studies require surface and near surface temperature data with high spatial and temporal resolution. The resolution of state of the art climate models and remote sensing data is often by far to coarse to represent the meso- and microscale distinctions of temperatures. This is particularly the case for regions with a huge variability of topoclimates, such as mountainous or urban areas. Statistical downscaling techniques are promising methods to refine gridded temperature data with limited spatial resolution, particularly due to their low demand for computer capacity. This paper presents two downscaling approaches - one for climate model output and one for remote sensing data. Both are methodically based on the FOSS-GIS platform SAGA. (orig.)

  18. Overview on high-resolution ocean modeling in JAMSTEC

    Institute of Scientific and Technical Information of China (English)

    Michio Kawamiya

    2014-01-01

    In view of the importance of ocean component for representing climate change,efforts are underway to implement a high-resolution nesting model system in Model for Interdisciplinary Research on Climate (MI-ROC) for the North Pacific using the same ocean model as used in the coupled model MIROC5. By comparing double (10 km for the northwestern Pacific,50 km for the rest of the Pacific) and triple (double nesting plus 2 km resolution near Japan) nesting,it turns out that relative vorticity is drastically enhanced near Japan with 2 km resolution. It is hoped that such an elaborated nesting system will reveal detailed processes for the ocean heat uptake by,e.g.,intermediate water and mode water formation for which the“perturbed region”near Japan is the key region.

  19. Advances toward high spectral resolution quantum X-ray calorimetry

    Science.gov (United States)

    Moseley, S. H.; Kelley, R. L.; Schoelkopf, R. J.; Szymkowiak, A. E.; Mccammon, D.

    1988-01-01

    Thermal detectors for X-ray spectroscopy combining high spectral resolution and quantum efficiency have been developed. These microcalorimeters measure the energy released in the absorption of a single photon by sensing the rise in temperature of a small absorbing structure. The ultimate energy resolution of such a device is limited by the thermodynamic power fluctuations in the thermal link between the calorimeter and isothermal bath and can in principle be made as low as 1 eV. The performance of a real device is degraded due to noise contributions such as excess 1/f noise in the thermistor and incomplete conversion of energy into phonons. The authors report some recent advances in thermometry, X-ray absorption and thermalization, fabrication techniques, and detector optimization in the presence of noise. These improvements have resulted in a device with a spectral resolution of 17 eV FWHM, measured at 6 keV.

  20. High Resolution Absorption Spectroscopy using Externally Dispersed Interferometry

    Energy Technology Data Exchange (ETDEWEB)

    Edelstein, J; Erskine, D J

    2005-07-06

    We describe the use of Externally Dispersed Interferometry (EDI) for high-resolution absorption spectroscopy. By adding a small fixed-delay interferometer to a dispersive spectrograph, a precise fiducial grid in wavelength is created over the entire spectrograph bandwidth. The fiducial grid interacts with narrow spectral features in the input spectrum to create a moire pattern. EDI uses the moire pattern to obtain new information about the spectra that is otherwise unavailable, thereby improving spectrograph performance. We describe the theory and practice of EDI instruments and demonstrate improvements in the spectral resolution of conventional spectrographs by a factor of 2 to 6. The improvement of spectral resolution offered by EDI can benefit space instruments by reducing spectrograph size or increasing instantaneous bandwidth.

  1. On temporal correlations in high-resolution frequency counting

    CERN Document Server

    Dunker, Tim; Rønningen, Ole Petter

    2016-01-01

    We analyze noise properties of time series of frequency data from different counting modes of a Keysight 53230A frequency counter. We use a 10 MHz reference signal from a passive hydrogen maser connected via phase-stable Huber+Suhner Sucoflex 104 cables to the reference and input connectors of the counter. We find that the high resolution gap-free (CONT) frequency counting process imposes long-term correlations in the output data, resulting in a modified Allan deviation that is characteristic of random walk phase noise. Equally important, the CONT mode results in a frequency bias. In contrast, the counter's undocumented raw continuous mode (RCON) yields unbiased frequency stability estimates with white phase noise characteristics, and of a magnitude consistent with the counter's 20 ps single-shot resolution. Furthermore, we demonstrate that a 100-point running average filter in conjunction with the RCON mode yields resolution enhanced frequency estimates with flicker phase noise characteristics. For instance,...

  2. High Resolution Software Defined Radar System for Target Detection

    Directory of Open Access Journals (Sweden)

    S. Costanzo

    2013-01-01

    Full Text Available The Universal Software Radio Peripheral USRP NI2920, a software defined transceiver so far mainly used in Software Defined Radio applications, is adopted in this work to design a high resolution L-Band Software Defined Radar system. The enhanced available bandwidth, due to the Gigabit Ethernet interface, is exploited to obtain a higher slant-range resolution with respect to the existing Software Defined Radar implementations. A specific LabVIEW application, performing radar operations, is discussed, and successful validations are presented to demonstrate the accurate target detection capability of the proposed software radar architecture. In particular, outdoor and indoor test are performed by adopting a metal plate as reference structure located at different distances from the designed radar system, and results obtained from the measured echo are successfully processed to accurately reveal the correct target position, with the predicted slant-range resolution equal to 6 m.

  3. Photoacoustic lymphatic imaging with high spatial-temporal resolution

    Science.gov (United States)

    Martel, Catherine; Yao, Junjie; Huang, Chih-Hsien; Zou, Jun; Randolph, Gwendalyn J.; Wang, Lihong V.

    2014-11-01

    Despite its critical function in coordinating the egress of inflammatory and immune cells out of tissues and maintaining fluid balance, the causative role of lymphatic network dysfunction in pathological settings is still understudied. Engineered-animal models and better noninvasive high spatial-temporal resolution imaging techniques in both preclinical and clinical studies will help to improve our understanding of different lymphatic-related pathologic disorders. Our aim was to take advantage of our newly optimized noninvasive wide-field fast-scanning photoacoustic (PA) microcopy system to coordinately image the lymphatic vasculature and its flow dynamics, while maintaining high resolution and detection sensitivity. Here, by combining the optical-resolution PA microscopy with a fast-scanning water-immersible microelectromechanical system scanning mirror, we have imaged the lymph dynamics over a large field-of-view, with high spatial resolution and advanced detection sensitivity. Depending on the application, lymphatic vessels (LV) were spectrally or temporally differentiated from blood vessels. Validation experiments were performed on phantoms and in vivo to identify the LV. Lymphatic flow dynamics in nonpathological and pathological conditions were also visualized. These results indicate that our newly developed PA microscopy is a promising tool for lymphatic-related biological research.

  4. High resolution imaging with impulse based thermoacoustic tomography

    Science.gov (United States)

    Kellnberger, Stephan; Hajiaboli, Amir; Sergiadis, George; Razansky, Daniel; Ntziachristos, Vasilis

    2011-07-01

    Existing imaging modalities like microwave- or radiofrequency (RF) induced thermoacoustic tomography systems show the potential for resolving structures deep inside tissue due to the high penetration properties of RF. However, one of the major drawbacks of existing thermoacoustic tomography systems with pulse modulated carrier frequency excitation is the compromise between efficient signal generation and attainable spatial resolution. In order to overcome limitations of conventional thermoacoustic imaging methods, we herein present and experimentally validate our novel approach towards high resolution thermoacoustic tomography. Instead of carrier-frequency amplification, we utilize ultrahigh-energy electromagnetic impulses at nanosecond duration with near-field energy coupling, thus maintaining thermoacoustic signal strength without compromising spatial resolution. Preliminary experiments on highly absorbing objects, consisting of copper wires with characteristic sizes of ~100 μm, reveal the resolution performance which yields 160 μm. Furthermore, benefits like its cost effectiveness, simplicity and compactness with the potential application in small animal imaging as well as human body imaging show that thermoacoustic tomography with impulse excitation is a promising imaging modality which has a broad range of applications.

  5. Validation of AIRS high-resolution stratospheric temperature retrievals

    Science.gov (United States)

    Meyer, Catrin I.; Hoffmann, Lars

    2014-10-01

    This paper focuses on stratospheric temperature observations by the Atmospheric InfraRed Sounder (AIRS) aboard NASA's Aqua satellite. We validate a nine-year record (2003 - 2011) of data retrieved with a scientific retrieval processor independent from the operational processor operated by NASA. The retrieval discussed here provides stratospheric temperature profiles for each individual AIRS footprint and has nine times better horizontal sampling than the operational data provided by NASA. The high-resolution temperature data are considered optimal for for gravity wave studies. For validation the high-resolution retrieval data are compared with results from the AIRS operational Level-2 data and the ERA-Interim meteorological reanalysis. Due to the large amount of data we performed statistical comparisons of monthly zonal mean cross-sections and time series. The comparisons show that the high-resolution temperature data are in good agreement with the validation data sets. The bias in the zonal averages is mostly within ±2K. The bias reaches a maximum of 7K to ERA-Interim and 4K to the AIRS operational data at the stratopause, it is related to the different resolutions of the data sets. Variability is nearly the same in all three data sets, having maximum standard deviations around the polar vortex in the mid and upper stratosphere. The validation presented here indicates that the high-resolution temperature retrievals are well-suited for scientific studies. In particular, we expect that they will become a valuable asset for future studies of stratospheric gravity waves.

  6. High Precision Current Measurement for Power Converters

    CERN Document Server

    Cerqueira Bastos, M

    2015-01-01

    The accurate measurement of power converter currents is essential to controlling and delivering stable and repeatable currents to magnets in particle accelerators. This paper reviews the most commonly used devices for the measurement of power converter currents and discusses test and calibration methods.

  7. Determination of minority-carrier lifetime and surface recombination velocity with high spacial resolution

    Science.gov (United States)

    Watanabe, M.; Actor, G.; Gatos, H. C.

    1977-01-01

    Quantitative analysis of the electron beam induced current in conjunction with high-resolution scanning makes it possible to evaluate the minority-carrier lifetime three dimensionally in the bulk and the surface recombination velocity two dimensionally, with a high spacial resolution. The analysis is based on the concept of the effective excitation strength of the carriers which takes into consideration all possible recombination sources. Two-dimensional mapping of the surface recombination velocity of phosphorus-diffused silicon diodes is presented as well as a three-dimensional mapping of the changes in the minority-carrier lifetime in ion-implanted silicon.

  8. High resolution simulations of extreme weather event in south Sardinia

    Science.gov (United States)

    Dessy, C.

    2010-05-01

    In the last decade, like most region of Mediterranean Europe, Sardinia has experienced severe precipitation events generating flash floods resulting in loss of lives and large economic damage. A numerical meteorological operational set-up is applied in the local weather service with the aim to improve the operational short range weather forecast of the Service with particular attention to intense, mostly rare and potentially severe, events. On the early hours of 22 October 2008 an intense and almost stationary mesoscale convective system interested particularly the south of Sardinia, heavy precipitation caused a flash flood with fatalities and numerous property damages. The event was particularly intense: about 400 mm of rain in 12 hours (a peak of 150 mm in an hour) were misured by the regional network of weather stations and these values appear extremely meaningfulls since those are about seven times the climatological monthly rainfall for that area and nearly the climatological annual rainfall. With the aim to improve significantly quantitative precipitation forecasting, it was evaluated a different set-up of a high resolution convection resolving model (MM5) initialised with different initial and boundary conditions (ECMWF and NCAR). In this paper it is discussed the meteorological system related to the mentioned event by using different numerical weather models (GCM and LAM) combined with conventional data, radar Doppler and Meteosat images. Preliminary results say that a different set-up of a non hydrostatic model can forecast severe convection events in advance of about one day and produce more realistic rainfall than that current operational and also improve the weather forecasts to respect the ECMWF-GCM. So it could drive an operational alert system in order to limit the risks associated with heavy precipitation events.

  9. High-resolution Josephson spectroscopy with a scanning tunneling microscope

    Science.gov (United States)

    Randeria, Mallika T.; Feldman, Benjamin E.; Drozdov, Ilya K.; Yazdani, Ali

    2015-03-01

    Conventional scanning tunneling microscopy (STM) measurements use a normal metal tip to probe local quasi-particle density of states with atomic resolution. Using a superconducting tip to conduct spectroscopy significantly boosts the energy resolution of the measurements, thus expanding the STM capabilities. Moreover, superconducting tips make it possible to probe superconductivity via the Josephson effect, which provides a direct measure of the local superconducting order parameter. Therefore, scanning Josephson spectroscopy measurements have the potential to characterize of a wide variety of superconducting materials on the atomic scale. I will present superconducting Pb tip measurements performed at temperatures below 250mK in a dilution refrigerator STM. By controlling the junction resistance, we are able to explore a wide range of tunneling regimes. Josephson measurements on Pb samples exhibit features including multiple Andreev reflections, and I will discuss the extension of these techniques to study atomic scale variations in Josephson current.

  10. The Gaia FGK Benchmark Stars - High resolution spectral library

    CERN Document Server

    Blanco-Cuaresma, S; Jofré, P; Heiter, U

    2014-01-01

    Context. An increasing number of high resolution stellar spectra is available today thanks to many past and ongoing spectroscopic surveys. Consequently, numerous methods have been developed in order to perform an automatic spectral analysis on a massive amount of data. When reviewing published results, biases arise and they need to be addressed and minimized. Aims. We are providing a homogeneous library with a common set of calibration stars (known as the Gaia FGK Benchmark Stars) that will allow to assess stellar analysis methods and calibrate spectroscopic surveys. Methods. High resolution and signal-to-noise spectra were compiled from different instruments. We developed an automatic process in order to homogenize the observed data and assess the quality of the resulting library. Results. We built a high quality library that will facilitate the assessment of spectral analyses and the calibration of present and future spectroscopic surveys. The automation of the process minimizes the human subjectivity and e...

  11. Design of UAV high resolution image transmission system

    Science.gov (United States)

    Gao, Qiang; Ji, Ming; Pang, Lan; Jiang, Wen-tao; Fan, Pengcheng; Zhang, Xingcheng

    2017-02-01

    In order to solve the problem of the bandwidth limitation of the image transmission system on UAV, a scheme with image compression technology for mini UAV is proposed, based on the requirements of High-definition image transmission system of UAV. The video codec standard H.264 coding module and key technology was analyzed and studied for UAV area video communication. Based on the research of high-resolution image encoding and decoding technique and wireless transmit method, The high-resolution image transmission system was designed on architecture of Android and video codec chip; the constructed system was confirmed by experimentation in laboratory, the bit-rate could be controlled easily, QoS is stable, the low latency could meets most applied requirement not only for military use but also for industrial applications.

  12. Automated data processing of high-resolution mass spectra

    DEFF Research Database (Denmark)

    Hansen, Michael Adsetts Edberg; Smedsgaard, Jørn

    There has been an almost explosive growth in performance and applications of Electrospray Ionization (ESI) Time of Flight (TOF) mass spectrometry, which today is one of the most efficient tools for screening of metabolites in complex bio-samples. Most efficiently ESI-MS can be used by directly...... infusion of crude extracts into the source taking advantage of the high sensitivity, high mass resolution and accuracy and the limited fragmentation. Unfortunately, there has not been a comparable development in the data processing techniques to fully exploit gain in high resolution and accuracy...... and mass axis on to a fixed one-dimensional array, we obtain a vector that can be used directly as input in multivariate statistics or library search methods. We demonstrate that both cluster- and discriminant analysis as well as PCA (and related methods) can be applied directly on mass spectra from direct...

  13. High Resolution Optical Spectra of HBC 722 after Outburst

    CERN Document Server

    Lee, Jeong-Eun; Lee, Sang-Gak; Sung, Hyun-Il; Lee, Byeong-Cheol; Sung, Hwankyung; Green, Joel D; Jeon, Young-Beom

    2011-01-01

    We report the results of our high resolution optical spectroscopic monitoring campaign ($\\lambda$ = 3800 -- 8800 A, R = 30000 -- 45000) of the new FU Orionis-type object HBC 722. We observed HBC 722 with the BOES 1.8-m telescope between 2010 November 26 and 2010 December 29 and FU Orionis itself on 2011 January 26. We detect a number of previously unreported high-resolution K I and Ca II lines beyond 7500 A. We resolve the H$\\alpha$ and Ca II line profiles into three velocity components, which we attribute to both disk and outflow. The increased accretion during outburst can heat the disk to produce the relatively narrow absorption feature and launch outflows appearing as high velocity blue and redshifted broad features.

  14. Application Research on High Resolution Radar Target Aggregation

    Directory of Open Access Journals (Sweden)

    Zhongzhi Li

    2010-11-01

    Full Text Available In high resolution radar system, the same target always has original data; so we need to merge multiple data from the same target as one target. Because of the system’s real-time requirement, we usually have to carry out target aggregation as quickly as possible. In this paper, we propose a quick target aggregation method based on clustering algorithm. The proposed method divides original data into subsets by single dimensional distance, and then merges subsets according to single dimensional distance and setdensity. At last we apply the proposed method to carry out target aggregation for airport scene surveillance radar system. Experimental result shows the proposed method has high execution efficiency and is not sensitive to noise data; it is useful for high resolution radar target aggregation.

  15. High Resolution X-ray-Induced Acoustic Tomography

    Science.gov (United States)

    Xiang, Liangzhong; Tang, Shanshan; Ahmad, Moiz; Xing, Lei

    2016-05-01

    Absorption based CT imaging has been an invaluable tool in medical diagnosis, biology, and materials science. However, CT requires a large set of projection data and high radiation dose to achieve superior image quality. In this letter, we report a new imaging modality, X-ray Induced Acoustic Tomography (XACT), which takes advantages of high sensitivity to X-ray absorption and high ultrasonic resolution in a single modality. A single projection X-ray exposure is sufficient to generate acoustic signals in 3D space because the X-ray generated acoustic waves are of a spherical nature and propagate in all directions from their point of generation. We demonstrate the successful reconstruction of gold fiducial markers with a spatial resolution of about 350 μm. XACT reveals a new imaging mechanism and provides uncharted opportunities for structural determination with X-ray.

  16. Imaging collagen type I fibrillogenesis with high spatiotemporal resolution.

    Science.gov (United States)

    Stamov, Dimitar R; Stock, Erik; Franz, Clemens M; Jähnke, Torsten; Haschke, Heiko

    2015-02-01

    Fibrillar collagens, such as collagen type I, belong to the most abundant extracellular matrix proteins and they have received much attention over the last five decades due to their large interactome, complex hierarchical structure and high mechanical stability. Nevertheless, the collagen self-assembly process is still incompletely understood. Determining the real-time kinetics of collagen type I formation is therefore pivotal for better understanding of collagen type I structure and function, but visualising the dynamic self-assembly process of collagen I on the molecular scale requires imaging techniques offering high spatiotemporal resolution. Fast and high-speed scanning atomic force microscopes (AFM) provide the means to study such processes on the timescale of seconds under near-physiological conditions. In this study we have applied fast AFM tip scanning to study the assembly kinetics of fibrillar collagen type I nanomatrices with a temporal resolution reaching eight seconds for a frame size of 500 nm. By modifying the buffer composition and pH value, the kinetics of collagen fibrillogenesis can be adjusted for optimal analysis by fast AFM scanning. We furthermore show that amplitude-modulation imaging can be successfully applied to extract additional structural information from collagen samples even at high scan rates. Fast AFM scanning with controlled amplitude modulation therefore provides a versatile platform for studying dynamic collagen self-assembly processes at high resolution. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. High-resolution ionization detector and array of such detectors

    Energy Technology Data Exchange (ETDEWEB)

    McGregor, Douglas S. (Ypsilanti, MI); Rojeski, Ronald A. (Pleasanton, CA)

    2001-01-16

    A high-resolution ionization detector and an array of such detectors are described which utilize a reference pattern of conductive or semiconductive material to form interaction, pervious and measurement regions in an ionization substrate of, for example, CdZnTe material. The ionization detector is a room temperature semiconductor radiation detector. Various geometries of such a detector and an array of such detectors produce room temperature operated gamma ray spectrometers with relatively high resolution. For example, a 1 cm.sup.3 detector is capable of measuring .sup.137 Cs 662 keV gamma rays with room temperature energy resolution approaching 2% at FWHM. Two major types of such detectors include a parallel strip semiconductor Frisch grid detector and the geometrically weighted trapezoid prism semiconductor Frisch grid detector. The geometrically weighted detector records room temperature (24.degree. C.) energy resolutions of 2.68% FWHM for .sup.137 Cs 662 keV gamma rays and 2.45% FWHM for .sup.60 Co 1.332 MeV gamma rays. The detectors perform well without any electronic pulse rejection, correction or compensation techniques. The devices operate at room temperature with simple commercially available NIM bin electronics and do not require special preamplifiers or cooling stages for good spectroscopic results.

  18. High-resolution electron microscopy of advanced materials

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, T.E.; Kung, H.H.; Sickafus, K.E.; Gray, G.T. III; Field, R.D.; Smith, J.F. [Los Alamos National Lab., NM (United States). Materials Science and Technology Div.

    1997-11-01

    This final report chronicles a three-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The High-Resolution Electron Microscopy Facility has doubled in size and tripled in quality since the beginning of the three-year period. The facility now includes a field-emission scanning electron microscope, a 100 kV field-emission scanning transmission electron microscope (FE-STEM), a 300 kV field-emission high-resolution transmission electron microscope (FE-HRTEM), and a 300 kV analytical transmission electron microscope. A new orientation imaging microscope is being installed. X-ray energy dispersive spectrometers for chemical analysis are available on all four microscopes; parallel electron energy loss spectrometers are operational on the FE-STEM and FE-HRTEM. These systems enable evaluation of local atomic bonding, as well as chemical composition in nanometer-scale regions. The FE-HRTEM has a point-to-point resolution of 1.6 {angstrom}, but the resolution can be pushed to its information limit of 1 {angstrom} by computer reconstruction of a focal series of images. HRTEM has been used to image the atomic structure of defects such as dislocations, grain boundaries, and interfaces in a variety of materials from superconductors and ferroelectrics to structural ceramics and intermetallics.

  19. High-resolution three-dimensional imaging with compress sensing

    Science.gov (United States)

    Wang, Jingyi; Ke, Jun

    2016-10-01

    LIDAR three-dimensional imaging technology have been used in many fields, such as military detection. However, LIDAR require extremely fast data acquisition speed. This makes the manufacture of detector array for LIDAR system is very difficult. To solve this problem, we consider using compress sensing which can greatly decrease the data acquisition and relax the requirement of a detection device. To use the compressive sensing idea, a spatial light modulator will be used to modulate the pulsed light source. Then a photodetector is used to receive the reflected light. A convex optimization problem is solved to reconstruct the 2D depth map of the object. To improve the resolution in transversal direction, we use multiframe image restoration technology. For each 2D piecewise-planar scene, we move the SLM half-pixel each time. Then the position where the modulated light illuminates will changed accordingly. We repeat moving the SLM to four different directions. Then we can get four low-resolution depth maps with different details of the same plane scene. If we use all of the measurements obtained by the subpixel movements, we can reconstruct a high-resolution depth map of the sense. A linear minimum-mean-square error algorithm is used for the reconstruction. By combining compress sensing and multiframe image restoration technology, we reduce the burden on data analyze and improve the efficiency of detection. More importantly, we obtain high-resolution depth maps of a 3D scene.

  20. Imaging collagen type I fibrillogenesis with high spatiotemporal resolution

    Energy Technology Data Exchange (ETDEWEB)

    Stamov, Dimitar R, E-mail: stamov@jpk.com [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany); Stock, Erik [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany); Franz, Clemens M [DFG-Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology (KIT), Wolfgang-Gaede-Strasse 1a, 76131 Karlsruhe (Germany); Jähnke, Torsten; Haschke, Heiko [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany)

    2015-02-15

    Fibrillar collagens, such as collagen type I, belong to the most abundant extracellular matrix proteins and they have received much attention over the last five decades due to their large interactome, complex hierarchical structure and high mechanical stability. Nevertheless, the collagen self-assembly process is still incompletely understood. Determining the real-time kinetics of collagen type I formation is therefore pivotal for better understanding of collagen type I structure and function, but visualising the dynamic self-assembly process of collagen I on the molecular scale requires imaging techniques offering high spatiotemporal resolution. Fast and high-speed scanning atomic force microscopes (AFM) provide the means to study such processes on the timescale of seconds under near-physiological conditions. In this study we have applied fast AFM tip scanning to study the assembly kinetics of fibrillar collagen type I nanomatrices with a temporal resolution reaching eight seconds for a frame size of 500 nm. By modifying the buffer composition and pH value, the kinetics of collagen fibrillogenesis can be adjusted for optimal analysis by fast AFM scanning. We furthermore show that amplitude-modulation imaging can be successfully applied to extract additional structural information from collagen samples even at high scan rates. Fast AFM scanning with controlled amplitude modulation therefore provides a versatile platform for studying dynamic collagen self-assembly processes at high resolution. - Highlights: • Continuous non-invasive time-lapse investigation of collagen I fibrillogenesis in situ. • Imaging of collagen I self-assembly with high spatiotemporal resolution. • Application of setpoint modulation to study the hierarchical structure of collagen I. • Observing real-time formation of the D-banding pattern in collagen I.

  1. MACHINE PROTECTION FOR HIGH AVERAGE CURRENT LINACS

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, Kevin; Allison, Trent; Evans, Richard; Coleman, James; Grippo, Albert

    2003-05-01

    A fully integrated Machine Protection System (MPS) is critical to efficient commissioning and safe operation of all high current accelerators. The Jefferson Lab FEL [1,2] has multiple electron beam paths and many different types of diagnostic insertion devices. The MPS [3] needs to monitor both the status of these devices and the magnet settings which define the beam path. The matrix of these devices and beam paths are programmed into gate arrays, the output of the matrix is an allowable maximum average power limit. This power limit is enforced by the drive laser for the photocathode gun. The Beam Loss Monitors (BLMs), RF status, and laser safety system status are also inputs to the control matrix. There are 8 Machine Modes (electron path) and 8 Beam Modes (average power limits) that define the safe operating limits for the FEL. Combinations outside of this matrix are unsafe and the beam is inhibited. The power limits range from no beam to 2 megawatts of electron beam power.

  2. Dispersal patterns in the North Sea, insights from a high resolution model

    Science.gov (United States)

    Mayorga Adame, Claudia Gabriela; Polton, Jeff; Holt, Jason; Graham, Jennifer; Henry, Lea-Anne

    2017-04-01

    Lagrangian particle tracking simulations are useful to elucidate the fate of materials transported by ocean currents ( i.e. larvae, pollutants, debris, drifters), and can therefore be useful to study important process in coastal seas. Dispersal patterns should be improved by the new generation of high horizontal resolution (ocean circulation models which provide an improved, more dynamic representation of the coastal ocean. We used the new high resolution Northwest European Shelf NEMO ocean circulation model and LTRANS, a particle tracking code, to study the effects of the increased resolution on the dispersion of Lagrangian particles in the North Sea. Particles were released at the locations of offshore oil and gas platforms in the North Sea and tracked for periods similar to the larval duration of benthic organisms that have colonized the subsea platforms. Dispersal patterns and spatio-temporal scales are identified for the summer (stratified) and winter (mixed) oceanographic regimes. The high resolution of the new NEMO model allows for fine scale detail of flow speed and variability. The small scale features (i.e. eddies and fronts) now represented in the model trap particles, decreasing their dispersal and increasing retention times in comparison to simulations done on a previous coarser resolution NEMO version (7 km AMM7). We isolated the effects of resolution from those due to different representations of the circulation in the different versions of the ocean circulation model by averaging the high resolution model velocity fields to the coarser (7 km) grid, and comparing the results of identical particle tracking experiments using these two flow fields. Our results provide a measure of the importance of high resolution flow fields when estimating transport of materials in an enclosed sea and provide a more realistic characterisation of dispersion in the North Sea.

  3. High-resolution infrared flash kinetic spectroscopy of OH radicals

    Energy Technology Data Exchange (ETDEWEB)

    Schiffman, A.; Nelson, D.D. Jr.; Robinson, M.S.; Nesbitt, D.J. (Univ. of Colorado, Boulder (United States) National Inst. of Standards and Tech., Boulder, CO (United States))

    1991-04-04

    A high-resolution infrared flash kinetic spectrometer is used for time- and frequency-resolved studies of the OH radical. OH is produced by 193-nm excimer laser photolysis of HNO{sub 3}/buffer gas mixtures in a 100-cm flow tube and is probed via weak fractional absorption of light from a widely tunable (2.35-3.59 {mu}m) single-mode ({Delta}{nu} {le} 2 MHz) color center laser. The IR absorption technique allows fast ({le}10{sup {minus}6} s), sensitive (<10{sup 9} radicals/cm{sup 3} per quantum state) detection of OH and is designed to permit determination of absolute OH number densities. The spectrometer is used to measure rate constants for the reactions of OH with ethane (k{sub 1}), propane (k{sub 2}), n-butane (k{sub 3}), and isobutane (k{sub 4}). The reliability of these measurements is tested on a variety of rotational, spin-orbit, and {lambda}-doublet states, with several buffer gases, and over more than an order of magnitude of alkane concentrations. The resulting rate constants are, in units of 10{sup {minus}12} cm{sup 3} molecule{sup {minus}1} s{sup {minus}1}, k{sub 1} = 0.243 {plus minus} 0.012, k{sub 2} = 1.02 {plus minus} 0.05, k{sub 3} = 2.35 {plus minus} 0.08, and k{sub 4} = 2.11 {plus minus} 0.09. The rate constants for the ethane, n-butane, and isobutane reactions agree with some previous determinations but are found to be between 10% and 25% lower than values currently used in atmospheric modeling; it is recommended that these values be revised to reflect the lower rates from this study. Current models of atmospheric air flow based on these rate constants, as well as those previously accepted values, are found to be inconsistent with daily changes in observed atmospheric alkane concentrations.

  4. Performance Optimization of NEMO Oceanic Model at High Resolution

    Science.gov (United States)

    Epicoco, Italo; Mocavero, Silvia; Aloisio, Giovanni

    2014-05-01

    The NEMO oceanic model is based on the Navier-Stokes equations along with a nonlinear equation of state, which couples the two active tracers (temperature and salinity) to the fluid velocity. The code is written in Fortan 90 and parallelized using MPI. The resolution of the global ocean models used today for climate change studies limits the prediction accuracy. To overcome this limit, a new high-resolution global model, based on NEMO, simulating at 1/16° and 100 vertical levels has been developed at CMCC. The model is computational and memory intensive, so it requires many resources to be run. An optimization activity is needed. The strategy requires a preliminary analysis to highlight scalability bottlenecks. It has been performed on a SandyBridge architecture at CMCC. An efficiency of 48% on 7K cores (the maximum available) has been achieved. The analysis has been also carried out at routine level, so that the improvement actions could be designed for the entire code or for the single kernel. The analysis highlighted for example a loss of performance due to the routine used to implement the north fold algorithm (i.e. handling the points at the north pole of the 3-poles Grids): indeed an optimization of the routine implementation is needed. The folding is achieved considering only the last 4 rows on the top of the global domain and by applying a rotation pivoting on the point in the middle. During the folding, the point on the top left is updated with the value of the point on bottom right and so on. The current version of the parallel algorithm is based on the domain decomposition. Each MPI process takes care of a block of points. Each process can update its points using values belonging to the symmetric process. In the current implementation, each received message is placed in a buffer with a number of elements equal to the total dimension of the global domain. Each process sweeps the entire buffer, but only a part of that computation is really useful for the

  5. Adaptive optics with pupil tracking for high resolution retinal imaging.

    Science.gov (United States)

    Sahin, Betul; Lamory, Barbara; Levecq, Xavier; Harms, Fabrice; Dainty, Chris

    2012-02-01

    Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics.

  6. High-resolution SIT TV tube for subnanosecond image shuttering

    Science.gov (United States)

    Yates, G. J.; Vine, B. H.; Aeby, I.; Dunbar, D. L.; King, N. S. P.; Jaramillo, S. A.; Thayer, N. N.; Noel, B. W.

    1984-09-01

    A new ultrafast high-resolution image shutter tube with reasonable gain and shuttering efficiency has been designed and tested. The design uses a grid-gated silicon-intensified-target (SIT) image section and a high-speed focus projection and scan (FPS) vidicon read-out section in one envelope to eliminate resolution losses from external coupling. The design features low-gate-interface capacity, a high-conductivity shutter grid, and a segmented low-resistivity photocathode for optimum gating speed. Optical gate widths as short as 400 ps + or - 100 ps for full shuttering of the 25-mm-diam input window with spatial resolution as high as 15 1p/mm have been measured. Some design criteria, most of the electrical and optical performance data for several variations in the basic design, and a comparison (of several key response functions) with similarly tested 18- and 25-mm-diam proximity-focused microchannel-plate (MCP) image intensifier tubes (MCPTs) are included.

  7. High resolution MAS-NMR in combinatorial chemistry.

    Science.gov (United States)

    Shapiro, M J; Gounarides, J S

    High-resolution magic angle spinning (hr-MAS) NMR is a powerful tool for characterizing organic reactions on solid support. Because magic angle spinning reduces the line-broadening due to dipolar coupling and variations in bulk magnetic susceptibility, line widths approaching those obtained in solution-phase NMR can be obtained. The magic angle spinning method is amenable for use in conjunction with a variety of NMR-pulse sequences, making it possible to perform full-structure determinations and conformational analysis on compounds attached to a polymer support. Diffusion-weighted MAS-NMR methods such as SPEEDY (Spin-Echo-Enhanced Diffusion-Filtered Spectroscopy) can be used to remove unwanted signals from the solvent, residual reactants, and the polymer support from the MAS-NMR spectrum, leaving only those signals arising from the resin-bound product. This review will present the applications of high-resolution magic angle spinning NMR for use in combinatorial chemistry research.

  8. High resolution reservoir geological modelling using outcrop information

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Changmin; Lin Kexiang; Liu Huaibo [Jianghan Petroleum Institute, Hubei (China)] [and others

    1997-08-01

    This is China`s first case study of high resolution reservoir geological modelling using outcrop information. The key of the modelling process is to build a prototype model and using the model as a geological knowledge bank. Outcrop information used in geological modelling including seven aspects: (1) Determining the reservoir framework pattern by sedimentary depositional system and facies analysis; (2) Horizontal correlation based on the lower and higher stand duration of the paleo-lake level; (3) Determining the model`s direction based on the paleocurrent statistics; (4) Estimating the sandbody communication by photomosaic and profiles; (6) Estimating reservoir properties distribution within sandbody by lithofacies analysis; and (7) Building the reservoir model in sandbody scale by architectural element analysis and 3-D sampling. A high resolution reservoir geological model of Youshashan oil field has been built by using this method.

  9. HIGH AND LOW RESOLUTION TEXTURED MODELS OF COMPLEX ARCHITECTURAL SURFACES

    Directory of Open Access Journals (Sweden)

    E. K. Stathopoulou

    2012-09-01

    Full Text Available During the recent years it has become obvious that 3D technology, applied mainly with the use of terrestrial laser scanners (TLS is the most suitable technique for the complete geometric documentation of complex objects, whether they are monuments or architectural constructions in general. However, it is rather a challenging task to convert an acquired point cloud into a realistic 3D polygonal model that can simultaneously satisfy high resolution modeling and visualization demands. The aim of the visualization of a simple or complex object is to create a 3D model that best describes the reality within the computer environment. This paper is dedicated especially in the visualization of a complex object's 3D model, through high, as well as low resolution textured models. The object of interest for this study was the Almoina (Romanesque Door of the Cathedral of Valencia in Spain.

  10. Fabricating High-Resolution X-Ray Collimators

    Science.gov (United States)

    Appleby, Michael; Atkinson, James E.; Fraser, Iain; Klinger, Jill

    2008-01-01

    A process and method for fabricating multi-grid, high-resolution rotating modulation collimators for arcsecond and sub-arcsecond x-ray and gamma-ray imaging involves photochemical machining and precision stack lamination. The special fixturing and etching techniques that have been developed are used for the fabrication of multiple high-resolution grids on a single array substrate. This technology has application in solar and astrophysics and in a number of medical imaging applications including mammography, computed tomography (CT), single photon emission computed tomography (SPECT), and gamma cameras used in nuclear medicine. This collimator improvement can also be used in non-destructive testing, hydrodynamic weapons testing, and microbeam radiation therapy.

  11. High-resolution ultrasonographic findings in thyroid nodules

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sun Seob; Lee, Kwan Seh; Kim, Kun Sang; Park, Soo Soung [College of Medicine, Chung-Ang University, Seoul (Korea, Republic of)

    1985-08-15

    Ultrasonography, it's excellent ability of differentiating cystic from solid lesion and depicting detailed architecture, proved itself useful in the diagnosis of thyroid pathologies. Advanced high resolution equipment made hidden small lesion detected and finer structure clearly seen. They seemed to throw light on the histological diagnosis of thyroid diseases, especially differentiation of benignancy and malignancy. Author reviewed pictures of high-resolution ultrasonography of thyroid disease (24 cases) and correlated them with proven pathological findings. The results were as follows: 1. Multiplicity of lesion favors benignancy (4 cases). 2. Well defined margin favors benignancy (14/17), while ill defined margin favors malignancy (3/4), and lesion of no margin favors thyroiditis (3/3). 3. Surrounding halo favors benignancy (7 cases). 4. Hypoechogenicity were found in most of malignancy and thyroiditis. Cystic components in solid nodule were common findings in benign and malignant lesions. Calcification was not found in malignancy.

  12. Temperature-dependent high resolution absorption cross sections of propane

    Science.gov (United States)

    Beale, Christopher A.; Hargreaves, Robert J.; Bernath, Peter F.

    2016-10-01

    High resolution (0.005 cm-1) absorption cross sections have been measured for pure propane (C3H8). These cross sections cover the 2550-3500 cm-1 region at five temperatures (from 296 to 700 K) and were measured using a Fourier transform spectrometer and a quartz cell heated by a tube furnace. Calibrations were made by comparison to the integrated cross sections of propane from the Pacific Northwest National Laboratory. These are the first high resolution absorption cross sections of propane for the 3 μm region at elevated temperatures. The cross sections provided may be used to monitor propane in combustion environments and in astronomical sources such as the auroral regions of Jupiter, brown dwarfs and exoplanets.

  13. High and Low Resolution Textured Models of Complex Architectural Surfaces

    Science.gov (United States)

    Stathopoulou, E. K.; Valanis, A.; Lerma, J. L.; Georgopoulos, A.

    2011-09-01

    During the recent years it has become obvious that 3D technology, applied mainly with the use of terrestrial laser scanners (TLS) is the most suitable technique for the complete geometric documentation of complex objects, whether they are monuments or architectural constructions in general. However, it is rather a challenging task to convert an acquired point cloud into a realistic 3D polygonal model that can simultaneously satisfy high resolution modeling and visualization demands. The aim of the visualization of a simple or complex object is to create a 3D model that best describes the reality within the computer environment. This paper is dedicated especially in the visualization of a complex object's 3D model, through high, as well as low resolution textured models. The object of interest for this study was the Almoina (Romanesque) Door of the Cathedral of Valencia in Spain.

  14. High Resolution Aircraft Scanner Mapping of Geothermal and Volcanic Areas

    Energy Technology Data Exchange (ETDEWEB)

    Mongillo, M.A.; Cochrane, G.R.; Wood, C.P.; Shibata, Y.

    1995-01-01

    High spectral resolution GEOSCAN Mkll multispectral aircraft scanner imagery has been acquired, at 3-6 m spatial resolutions, over much of the Taupo Volcanic Zone as part of continuing investigations aimed at developing remote sensing techniques for exploring and mapping geothermal and volcanic areas. This study examined the 24-band: visible, near-IR (NIR), mid-IR (MIR) and thermal-IR (TIR) imagery acquired over Waiotapu geothermal area (3 m spatial resolution) and White Island volcano (6 m resolution). Results show that color composite images composed of visible and NIR wavelengths that correspond to color infrared (CIR) photographic wavelengths can be useful for distinguishing among bare ground, water and vegetation features and, in certain cases, for mapping various vegetation types. However, combinations which include an MIR band ({approx} 2.2 {micro}m) with either visible and NIR bands, or two NIR bands, are the most powerful for mapping vegetation types, water bodies, and bare and hydrothermally altered ground. Combinations incorporating a daytime TIR band with NIR and MIR bands are also valuable for locating anomalously hot features and distinguishing among different types of surface hydrothermal alteration.

  15. A high resolution cavity BPM for the CLIC Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Chritin, N.; Schmickler, H.; Soby, L.; /CERN; Lunin, A.; Solyak, N.; Wendt, M.; Yakovlev, V.; /Fermilab

    2010-08-01

    In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.

  16. High-Resolution Wind Measurements for Offshore Wind Energy Development

    Science.gov (United States)

    Nghiem, Son V.; Neumann, Gregory

    2011-01-01

    A mathematical transform, called the Rosette Transform, together with a new method, called the Dense Sampling Method, have been developed. The Rosette Transform is invented to apply to both the mean part and the fluctuating part of a targeted radar signature using the Dense Sampling Method to construct the data in a high-resolution grid at 1-km posting for wind measurements over water surfaces such as oceans or lakes.

  17. High resolution solar soft X-ray spectrometer

    Institute of Scientific and Technical Information of China (English)

    ZHANG Fei; WANG Huan-Yu; PENG Wen-Xi; LIANG Xiao-Hua; ZHANG Chun-Lei; CAO Xue-Lei; JIANG Wei-Chun; ZHANG Jia-Yu; CUI Xing-Zhu

    2012-01-01

    A high resolution solar soft X-ray spectrometer (SOX) payload onboard a satellite is developed.A silicon drift detector (SDD) is adopted as the detector of the SOX spectrometer.The spectrometer consists of the detectors and their readout electronics,a data acquisition unit and a payload data handling unit.A ground test system is also developed to test SOX.The test results show that the design goals of the spectrometer system have been achieved.

  18. High resolution bathymetry of China seas and their surroundings

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Based on the oceanic lithospheric flexure and the worldwide bathymetric data ETOPO5, the high resolu tion bathymetry of the China seas and their surroundings is computed from altimeter derived gravity anomalies. The new bathymetry obtained by this study is higher resolution and accuracy than the widely used ETOPO5 data, mean while it shows clearly the seafioor, the tectonic characteristics and the geodynamical processes in the China seas.

  19. High-resolution x-ray photoemission spectra of silver

    DEFF Research Database (Denmark)

    Barrie, A.; Christensen, N. E.

    1976-01-01

    An electron spectrometer fitted with an x-ray monochromator for Al Kα1,2 radiation (1486.6 eV) has been used to record high-resolution x-ray photoelectron spectra for the 4d valence band as well as the 3d spin doublet in silver. The core-level spectrum has a line shape that can be described...

  20. High resolution inelastic electron scattering and nuclear structure

    Science.gov (United States)

    Blok, H. B.; Heisenberg, J. H.

    Thanks to the improved characteristics of the experimental set-up electron scattering has become an excellent tool to study the structure of the nucleus. After describing globally how the nuclear structure enters in the formalism of (e,e') reactions and how the high experimental resolution is obtained, several examples of the use of electron scattering for the study of specific nuclear structure questions are discussed.

  1. Tuberculous otitis media: findings on high-resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Lungenschmid, D. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Buchberger, W. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Schoen, G. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria); Schoepf, R. [Radiologic Inst., Landeck (Austria); Mihatsch, T. [Dept. of Oto-Rhino-Laryngology, University Hospital of Innsbruck (Austria); Birbamer, G. [Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Wicke, K. [Inst. of Computed Tomography, University Hospital of Innsbruck (Austria)

    1993-12-01

    We describe two cases of tuberculous otitis media studied with high-resolution computed tomography (CT). Findings included extensive soft tissue densities with fluid levels in the tympanic cavity, the antrum, the mastoid and petrous air cells. Multifocal bony erosions and reactive bone sclerosis were seen as well. CT proved valuable for planning therapy by accurately displaying the involvement of the various structures of the middle and inner ear. However, the specific nature of the disease could only be presumed. (orig.)

  2. Fusion Experiments of HSI and High Resolution Panchromatic Imagery

    Science.gov (United States)

    2007-11-02

    map derived from the unsharpened HSI. The classification is performed with an unsupervised feature extraction using principal component analysis (PCA... Classification of Hyperspectral Data in Urban Area", P. 169-172, SPIE Vol.3502 8. R. C. Gonzalez, P. Wintz, Digital Image Processing, Addison-Wesley...MA 02420-9185 Abstract In this paper, the fusion of hyperspectral imaging (HSI) sensor data and high-resolution panchromatic imagery (HPI) is

  3. Optical alignment of high resolution Fourier transform spectrometers

    Science.gov (United States)

    Breckinridge, J. B.; Ocallaghan, F. G.; Cassie, A. G.

    1980-01-01

    Remote sensing, high resolution FTS instruments often contain three primary optical subsystems: Fore-Optics, Interferometer Optics, and Post, or Detector Optics. We discuss the alignment of a double-pass FTS containing a cat's-eye retro-reflector. Also, the alignment of fore-optics containing confocal paraboloids with a reflecting field stop which relays a field image onto a camera is discussed.

  4. A high resolution cavity BPM for the CLIC Test Facility

    CERN Document Server

    Chritin, N; Soby, L; Lunin, A; Solyak, N; Wendt, M; Yakovlev, V

    2012-01-01

    In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.

  5. Chronic pneumonitis of infancy: high-resolution CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, Oeystein E.; Owens, Catherine M. [Radiology Department, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, WC1N 3JH, London (United Kingdom); Sebire, Neil J. [Histopathology Department, Great Ormond Street Hospital for Children NHS Trust, London (United Kingdom); Jaffe, Adam [Portex Respiratory Medicine Unit, The Institute of Child Health, University College London, London (United Kingdom)

    2004-01-01

    Chronic pneumonitis of infancy (CPI) is a very rare entity. We report the chest radiography and high-resolution CT (HRCT) findings in an infant with histopathologically confirmed CPI. The child was admitted for intensive care 18 h after birth and died at 39 days of age. On HRCT there was diffuse ground-glass change, interlobular septal thickening and discrete centrilobular nodules. An accurate diagnosis is crucial for correct management; however, several entities with the same HRCT findings are recognized. (orig.)

  6. High-resolution CT of lesions of the optic nerve

    Energy Technology Data Exchange (ETDEWEB)

    Peyster, R.G.; Hoover, E.D.; Hershey, B.L.; Haskin, M.E.

    1983-05-01

    The optic nerves are well demonstrated by high-resolution computed tomography. Involvement of the optic nerve by optic gliomas and optic nerve sheath meningiomas is well known. However, nonneoplastic processes such as increased intracranial pressure, optic neuritis, Grave ophthalmopathy, and orbital pseudotumor may also alter the appearance of the optic nerve/sheath on computed tomography. Certain clinical and computed tomographic features permit distinction of these nonneoplastic tumefactions from tumors.

  7. Yeast expression proteomics by high-resolution mass spectrometry

    DEFF Research Database (Denmark)

    Walther, Tobias C; Olsen, Jesper Velgaard; Mann, Matthias

    2010-01-01

    -translational controls contribute majorly to regulation of protein abundance, for example in heat shock stress response. The development of new sample preparation methods, high-resolution mass spectrometry and novel bioinfomatic tools close this gap and allow the global quantitation of the yeast proteome under different...... conditions. Here, we provide background information on proteomics by mass-spectrometry and describe the practice of a comprehensive yeast proteome analysis....

  8. Progress Toward A Very High Angular Resolution Imaging Spectrometer (VERIS)

    Science.gov (United States)

    Korendyke, Clarence M.; Vourlidas, A.; Landi, E.; Seely, J.; Klimchuck, J.

    2007-07-01

    Recent imaging at arcsecond (TRACE) and sub-arcsecond (VAULT) spatial resolution clearly show that structures with fine spatial scales play a key role in the physics of the upper solar atmosphere. Both theoretical and observational considerations point to the importance of small spatial scales, impulsive energy release, strong dynamics, and extreme plasma nonuniformity. Fundamental questions regarding the nature, structure, properties and dynamics of loops and filamentary structures in the upper atmosphere have been raised. To address these questions, we are developing a next generation, VEry high angular Resolution Imaging Spectrometer (VERIS) as a sounding rocket instrument. VERIS will obtain the necessary high spatial resolution, high fidelity measurements of plasma temperatures, densities and velocities. With broad simultaneous temperature coverage, the VERIS observations will directly address unresolved issues relating to interconnections of various temperature solar plasmas. VERIS will provide the first ever subarcsecond spectra of transition region and coronal structures. It will do so with a sufficient spectral resolution of to allow centroided Doppler velocity determinations to better than 3 km/s. VERIS uses a novel two element, normal incidence optical design with highly reflective EUV coatings to access a spectral range with broad temperature coverage (0.03-15 MK) and density-sensitive line ratios. Finally, in addition to the spectra, VERIS will simultaneously obtain spectrally pure slot images (10x150 arcsec) in the +/-1 grating orders, which can be combined to make instantaneous line-of-sight velocity maps with 8km/s accuracy over an unprecedented field of view. The VERIS program is beginning the second year of its three year development cycle. All design activities and reviews are complete. Fabrication of all major components has begun. Brassboard electronics cards have been fabricated, assembled and tested. The paper presents the essential scientific

  9. Thermal currents in highly correlated systems

    OpenAIRE

    MORENO, J; Coleman, P.

    1996-01-01

    Conventional approaches to thermal conductivity in itinerant systems neglect the contribution to thermal current due to interactions. We derive this contribution to the thermal current and show how it produces important corrections to the thermal conductivity in anisotropic superconductors. We discuss the possible relevance of these corrections for the interpretation of the thermal conductivity of anisotropic superconductors.

  10. High Spectral Resolution, High Cadence, Imaging X-ray Microcalorimeters for Solar Physics - Phase 2 Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcalorimeter x-ray instruments are non-dispersive, high spectral resolution, broad-band, high cadence imaging spectrometers. We have been developing these...

  11. Fine-resolution simulation of surface current and sea ice in the Arctic Mediterranean Seas

    Institute of Scientific and Technical Information of China (English)

    LIU Xiying; ZHANG Xuehong; YU Rucong; LIU Hailong; LI Wei

    2007-01-01

    A fine-resolution model is developed for ocean circulation simulation in the National Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics (LASG),Chinese Academy of Sciences, and is applied to simulate surface current and sea ice variations in the Arctic Mediterranean Seas. A dynamic sea ice model in elastic-viscous-plastic rheology and a thermodynamic sea ice model are employed. A 200-year simulation is performed and a dimatological average of a 10-year period (141 st-150 th) is presented with focus on sea ice concentration and surface current variations in the Arctic Mediterranean Seas. The model is able to simulate well the East Greenland Current, Beaufort Gyre and the Transpolar Drift, but the simulated West Spitsbergen Current is small and weak. In the March climatology, the sea ice coverage can be simulated well except for a bit more ice in east of Spitsbergen Island. The result is also good for the September scenario except for less ice concentration east of Greenland and greater ice concentration near the ice margin. The extra ice east of Spitsbergen Island is caused by sea ice current convergence forced by atmospheric wind stress.

  12. A high-resolution record of Greenland mass balance

    Science.gov (United States)

    McMillan, Malcolm; Leeson, Amber; Shepherd, Andrew; Briggs, Kate; Armitage, Thomas W. K.; Hogg, Anna; Kuipers Munneke, Peter; Broeke, Michiel; Noël, Brice; Berg, Willem Jan; Ligtenberg, Stefan; Horwath, Martin; Groh, Andreas; Muir, Alan; Gilbert, Lin

    2016-07-01

    We map recent Greenland Ice Sheet elevation change at high spatial (5 km) and temporal (monthly) resolution using CryoSat-2 altimetry. After correcting for the impact of changing snowpack properties associated with unprecedented surface melting in 2012, we find good agreement (3 cm/yr bias) with airborne measurements. With the aid of regional climate and firn modeling, we compute high spatial and temporal resolution records of Greenland mass evolution, which correlate (R = 0.96) with monthly satellite gravimetry and reveal glacier dynamic imbalance. During 2011-2014, Greenland mass loss averaged 269 ± 51 Gt/yr. Atmospherically driven losses were widespread, with surface melt variability driving large fluctuations in the annual mass deficit. Terminus regions of five dynamically thinning glaciers, which constitute less than 1% of Greenland's area, contributed more than 12% of the net ice loss. This high-resolution record demonstrates that mass deficits extending over small spatial and temporal scales have made a relatively large contribution to recent ice sheet imbalance.

  13. High resolution ultrasonic spectroscopy system for nondestructive evaluation

    Science.gov (United States)

    Chen, C. H.

    1991-01-01

    With increased demand for high resolution ultrasonic evaluation, computer based systems or work stations become essential. The ultrasonic spectroscopy method of nondestructive evaluation (NDE) was used to develop a high resolution ultrasonic inspection system supported by modern signal processing, pattern recognition, and neural network technologies. The basic system which was completed consists of a 386/20 MHz PC (IBM AT compatible), a pulser/receiver, a digital oscilloscope with serial and parallel communications to the computer, an immersion tank with motor control of X-Y axis movement, and the supporting software package, IUNDE, for interactive ultrasonic evaluation. Although the hardware components are commercially available, the software development is entirely original. By integrating signal processing, pattern recognition, maximum entropy spectral analysis, and artificial neural network functions into the system, many NDE tasks can be performed. The high resolution graphics capability provides visualization of complex NDE problems. The phase 3 efforts involve intensive marketing of the software package and collaborative work with industrial sectors.

  14. Multimodal microscopy with high resolution spectral focusing CARS

    Science.gov (United States)

    Baldacchini, Tommaso; Zadoyan, Ruben

    2014-02-01

    In this work we describe a device that extends capabilities of multiphoton microscopes based on dual wavelength output femtosecond laser sources. CARS with 17cm-1 spectral resolution is experimentally demonstrated. Our approach is based on spectral focusing CARS. For pulse shaping of the pump and Stokes beams we utilize transmission gratings based stretcher. It allows the dispersion of the stretcher to be continuously adjusted in wide range. The best spectral resolution is achieved when the chirp rates in both pump and Stokes beam are matched. The device is automated. Any change in the beam path lengths due to the stretcher adjustment or wavelength tuning is compensated by the delay line. We incorporated into the device a computer controlled beam pointing stabilization system that compensates the beam pointing deviation due to dispersion in the system. High level of automation and computer control makes the operation of the device easy. We present CARS images of several samples that demonstrate high spectral resolution, high contrast and chemical selectivity.

  15. High resolution, large dynamic range field map estimation

    Science.gov (United States)

    Dagher, Joseph; Reese, Timothy; Bilgin, Ali

    2013-01-01

    Purpose We present a theory and a corresponding method to compute high resolution field maps over a large dynamic range. Theory and Methods We derive a closed-form expression for the error in the field map value when computed from two echoes. We formulate an optimization problem to choose three echo times which result in a pair of maximally distinct error distributions. We use standard field mapping sequences at the prescribed echo times. We then design a corresponding estimation algorithm which takes advantage of the optimized echo times to disambiguate the field offset value. Results We validate our method using high resolution images of a phantom at 7T. The resulting field maps demonstrate robust mapping over both a large dynamic range, and in low SNR regions. We also present high resolution offset maps in vivo using both, GRE and MEGE sequences. Even though the proposed echo time spacings are larger than the well known phase aliasing cutoff, the resulting field maps exhibit a large dynamic range without the use of phase unwrapping or spatial regularization techniques. Conclusion We demonstrate a novel 3-echo field map estimation method which overcomes the traditional noise-dynamic range trade-off. PMID:23401245

  16. High Resolution CO Observations of Massive Star Forming Regions

    CERN Document Server

    Klaassen, P D; Keto, E R; Zhang, Q; Galván-Madrid, R; Liu, H-Y B

    2011-01-01

    Context. To further understand the processes involved in the formation of massive stars, we have undertaken a study of the gas dynamics surrounding three massive star forming regions. By observing the large scale structures at high resolution, we are able to determine properties such as driving source, and spatially resolve the bulk dynamical properties of the gas such as infall and outflow. Aims. With high resolution observations, we are able to determine which of the cores in a cluster forming massive stars is responsible for the large scale structures. Methods. We present CO observations of three massive star forming regions with known HII regions and show how the CO traces both infall and outflow. By combining data taken in two SMA configurations with JCMT observations, we are able to see large scale structures at high resolution. Results. We find large (0.26-0.40 pc), massive (2-3 M_sun) and energetic (13-17 \\times 10^44 erg) outflows emanating from the edges of two HII regions suggesting they are being ...

  17. High-Resolution CH Observations of Two Translucent Molecular Clouds

    Science.gov (United States)

    Chastain, Raymond J.; Cotten, David; Magnani, Loris

    2010-01-01

    We present high-resolution (1farcm3 × 1farcm6) observations of the CH 2Π1/2 (F = 1-1) emission line at 3335 MHz in two high-latitude translucent clouds, MBM 3 and 40. At the assumed cloud distances, the angular resolution corresponds to ~0.05 pc, nearly an order of magnitude better than previous studies. Comparisons of the CH emission with previously obtained CO(1-0) data are difficult to interpret: the CO and CH line emission correlates in MBM 40 but not in MBM 3. In both clouds, there is a spatial offset in the peak emission, and perhaps in velocity for MBM 40. The difference in emission characteristics for the two tracers are noticeable in these two nearby clouds because of the high spatial resolution. Since both CH and CO are deemed to be reliable tracers of H2, our results indicate that more care should be taken when using one of these tracers to determine the mass of a nearby molecular cloud.

  18. Towards a Global High Resolution Peatland Map in 2020

    Science.gov (United States)

    Barthelmes, Alexandra; Barthelmes, Karen-Doreen; Joosten, Hans; Dommain, Rene; Margalef, Olga

    2015-04-01

    Some 3% of land area on planet Earth (approx. 4 million km2) is covered by peatlands. About 10% (~ 0.3 % of the land area) are drained and responsible for a disproportional 5 % of the global anthropogenic CO2 emissions (Victoria et al., 2012). Additionally, peatland drainage and degradation lead to land subsidence, soil degradation, water pollution, and enhanced susceptibility to fire (Holden et al., 2004; Joosten et al., 2012). The global importance of peatlands for carbon storage and climate change mitigation has currently been recognized in international policy - since 2008 organic soils are subject of discussion in the UN Framework Convention on Climate Change (UNFCCC) (Joosten, 2011). In May 2013 the European Parliament decided that the global post 2020 climate agreement should include the obligation to report emissions and removals from peatland drainage and rewetting. Implementation of such program, however, necessitates the rapid availability of reliable, comprehensive, high resolution, spatially explicit data on the extent and status of peatlands. For many reporting countries this requires an innovation in peatland mapping, i.e. the better and integrative use of novel, but already available methods and technologies. We developed an approach that links various science networks, methodologies and data bases, including those of peatland/landscape ecology for understanding where and how peatlands may occur, those of remote sensing for identifying possible locations, and those of pedology (legacy soil maps) and (palaeo-)ecology for ground truthing. Such integration of old field data, specialized knowledge, and modern RS and GIS technologies enables acquiring a rapid, comprehensive, detailed and rather reliable overview, even on a continental scale. We illustrate this approach with a high resolution overview of peatland distribution, area, status and greenhouse gas fluxes e.g. for the East African countries Rwanda, Burundi, Uganda and Zambia. Furthermore, we

  19. The Impact of Horizontal and Temporal Resolution on Convection and Precipitation with High-Resolution GEOS-5

    Science.gov (United States)

    Putman, William P.

    2012-01-01

    Using a high-resolution non-hydrostatic version of GEOS-5 with the cubed-sphere finite-volume dynamical core, the impact of spatial and temporal resolution on cloud properties will be evaluated. There are indications from examining convective cluster development in high resolution GEOS-5 forecasts that the temporal resolution within the model may playas significant a role as horizontal resolution. Comparing modeled convective cloud clusters versus satellite observations of brightness temperature, we have found that improved. temporal resolution in GEOS-S accounts for a significant portion of the improvements in the statistical distribution of convective cloud clusters. Using satellite simulators in GEOS-S we will compare the cloud optical properties of GEOS-S at various spatial and temporal resolutions with those observed from MODIS. The potential impact of these results on tropical cyclone formation and intensity will be examined as well.

  20. Development of high resolution land surface parameters for the Community Land Model

    Directory of Open Access Journals (Sweden)

    Y. Ke

    2012-06-01

    Full Text Available There is a growing need for high-resolution land surface parameters as land surface models are being applied at increasingly higher spatial resolution offline as well as in regional and global models. The default land surface parameters for the most recent version of the Community Land Model (i.e. CLM 4.0 are at 0.5° or coarser resolutions, released with the model from the National Center for Atmospheric Research (NCAR. Plant Functional Types (PFTs, vegetation properties such as Leaf Area Index (LAI, Stem Area Index (SAI, and non-vegetated land covers were developed using remotely-sensed datasets retrieved in late 1990's and the beginning of this century. In this study, we developed new land surface parameters for CLM 4.0, specifically PFTs, LAI, SAI and non-vegetated land cover composition, at 0.05° resolution globally based on the most recent MODIS land cover and improved MODIS LAI products. Compared to the current CLM 4.0 parameters, the new parameters produced a decreased coverage by bare soil and trees, but an increased coverage by shrub, grass, and cropland. The new parameters result in a decrease in global seasonal LAI, with the biggest decrease in boreal forests; however, the new parameters also show a large increase in LAI in tropical forest. Differences between the new and the current parameters are mainly caused by changes in the sources of remotely sensed data and the representation of land cover in the source data. The new high-resolution land surface parameters have been used in a coupled land-atmosphere model (WRF-CLM applied to the western US to demonstrate their use in high-resolution modeling. Future work will include global offline CLMsimulations to examine the impacts of source data resolution and subsequent land parameter changes on simulated land surface processes.

  1. High Resolution Real Time Sonography of the Thyroid Gland

    Directory of Open Access Journals (Sweden)

    A. Honarbakhsh

    2008-01-01

    Full Text Available Background/Objective: High-resolution sonography equipment permits for visualization of normal and abnormal thyroid gland with or without gel pad or water bath. This study prospectively presents surgically and pathologically proved patients with thyroid disease by direct ultrasound with or without Doppler (pulse, color, power Doppler."nPatients and Methods: This study was performed by 7.5-10 MHz frequency linear probe transducer with axial resolution of 0.7mm and lateral resolution of 1-2 mm (Aloka 650 and super SG 140 Toshiba unit assembly with color, power Doppler. Patient's neck was extended as a supine position."nResults: Pathologic proof was obtained in 45 patients with benign and five patients with malignant thyroid disease. Benign lesions were follicular adenoma in 30 patients, goiter in 10 patients, as hashimoto thyroiditis in two patients, hemorrhagic cyst in two patients and simple cyst in one patient. Malignant lesions were follicular, papillary, and medulary carcinoma which seen in two, two, and one patients respectively. Echopatterns were as follow: Most of them showed decreades echo when we compare to normal thyroid tissue, some malignant lesions showed increased echo and some isoecho, in the last group we need other work up for example Doppler (pulse, color, power for evaluation vascularity. We did not have metastasis to thyroid gland."nConclusion: With advace in technology in crystal and design overall probe as a result creat broadband width probe and also full digital sonography unit inclding (beam forming - CPU in images resolution is with high grade than semi digital unit that before used for thytoid gland. When With any reason resolution is increased we sould be able to diagnosed very small and smallest lesion (for example mest to thyroid or reccurency after total Lobectomy: there is three primay uses of sonography, 1 detection of mutionodular gland when only one nodule is suspected clinically and by isotop scan.2 High

  2. High resolution modeling of a small urban catchment

    Science.gov (United States)

    Skouri-Plakali, Ilektra; Ichiba, Abdellah; Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

    2016-04-01

    Flooding is one of the most complex issues that urban environments have to deal with. In France, flooding remains the first natural risk with 72% of decrees state of natural disaster issued between October 1982 and mid-November 2014. Flooding is a result of meteorological extremes that are usually aggravated by the hydrological behavior of urban catchments and human factors. The continuing urbanization process is indeed changing the whole urban water cycle by limiting the infiltration and promoting runoff. Urban environments are very complex systems due to their extreme variability, the interference between human activities and natural processes but also the effect of the ongoing urbanization process that changes the landscape and hardly influences their hydrologic behavior. Moreover, many recent works highlight the need to simulate all urban water processes at their specific temporal and spatial scales. However, considering urban catchments heterogeneity still challenging for urban hydrology, even after advances noticed in term of high-resolution data collection and computational resources. This issue is more to be related to the architecture of urban models being used and how far these models are ready to take into account the extreme variability of urban catchments. In this work, high spatio-temporal resolution modeling is performed for a small and well-equipped urban catchment. The aim of this work is to identify urban modeling needs in terms of spatial and temporal resolution especially for a very small urban area (3.7 ha urban catchment located in the Perreux-sur-Marne city at the southeast of Paris) MultiHydro model was selected to carry out this work, it is a physical based and fully distributed model that interacts four existing modules each of them representing a portion of the water cycle in urban environments. MultiHydro was implemented at 10m, 5m and 2m resolution. Simulations were performed at different spatio-temporal resolutions and analyzed with

  3. A versatile high resolution scanning tunneling potentiometry implementation.

    Science.gov (United States)

    Druga, T; Wenderoth, M; Homoth, J; Schneider, M A; Ulbrich, R G

    2010-08-01

    We have developed a new scanning tunneling potentiometry technique which can-with only minor changes of the electronic setup-be easily added to any standard scanning tunneling microscope (STM). This extension can be combined with common STM techniques such as constant current imaging or scanning tunneling spectroscopy. It is capable of performing measurements of the electrochemical potential with microvolt resolution. Two examples demonstrate the versatile application. First of all, we have determined local variations of the electrochemical potential due to charge transport of biased samples down to angstrom length scales. Second, with tip and sample at different temperatures we investigated the locally varying thermovoltage occurring at the tunneling junction. Aside from its use in determining the chemical identity of substances at the sample surface our method provides a controlled way to eliminate the influence of laterally varying thermovoltages on low-bias constant current topographies.

  4. Distributed Modeling with Parflow using High Resolution LIDAR Data

    Science.gov (United States)

    Barnes, M.; Welty, C.; Miller, A. J.

    2012-12-01

    Urban landscapes provide a challenging domain for the application of distributed surface-subsurface hydrologic models. Engineered water infrastructure and altered topography influence surface and subsurface flow paths, yet these effects are difficult to quantify. In this work, a parallel, distributed watershed model (ParFlow) is used to simulate urban watersheds using spatial data at the meter and sub-meter scale. An approach using GRASS GIS (Geographic Resources Analysis Support System) is presented that incorporates these data to construct inputs for the ParFlow simulation. LIDAR topography provides the basis for the fully coupled overland flow simulation. Methods to address real discontinuities in the urban land-surface for use with the grid-based kinematic wave approximation used in ParFlow are presented. The spatial distribution of impervious surface is delineated accurately from high-resolution land cover data; hydrogeological properties are specified from literature values. An application is presented for part of the Dead Run subwatershed of the Gwynns Falls in Baltimore County, MD. The domain is approximately 3 square kilometers, and includes a highly impacted urban stream, a major freeway, and heterogeneous urban development represented at a 10-m horizontal resolution and 1-m vertical resolution. This resolution captures urban features such as building footprints and highways at an appropriate scale. The Dead Run domain provides an effective test case for ParFlow application at the fine scale in an urban environment. Preliminary model runs employ a homogeneous subsurface domain with no-flow boundaries. Initial results reflect the highly articulated topography of the road network and the combined influence of surface runoff from impervious surfaces and subsurface flux toward the channel network. Subsequent model runs will include comparisons of the coupled surface-subsurface response of alternative versions of the Dead Run domain with and without impervious

  5. High resolution OCT image generation using super resolution via sparse representation

    Science.gov (United States)

    Asif, Muhammad; Akram, Muhammad Usman; Hassan, Taimur; Shaukat, Arslan; Waqar, Razi

    2017-02-01

    In this paper we propose a technique for obtaining a high resolution (HR) image from a single low resolution (LR) image -using joint learning dictionary - on the basis of image statistic research. It suggests that with an appropriate choice of an over-complete dictionary, image patches can be well represented as a sparse linear combination. Medical imaging for clinical analysis and medical intervention is being used for creating visual representations of the interior of a body, as well as visual representation of the function of some organs or tissues (physiology). A number of medical imaging techniques are in use like MRI, CT scan, X-rays and Optical Coherence Tomography (OCT). OCT is one of the new technologies in medical imaging and one of its uses is in ophthalmology where it is being used for analysis of the choroidal thickness in the eyes in healthy and disease states such as age-related macular degeneration, central serous chorioretinopathy, diabetic retinopathy and inherited retinal dystrophies. We have proposed a technique for enhancing the OCT images which can be used for clearly identifying and analyzing the particular diseases. Our method uses dictionary learning technique for generating a high resolution image from a single input LR image. We train two joint dictionaries, one with OCT images and the second with multiple different natural images, and compare the results with previous SR technique. Proposed method for both dictionaries produces HR images which are comparatively superior in quality with the other proposed method of SR. Proposed technique is very effective for noisy OCT images and produces up-sampled and enhanced OCT images.

  6. Development of an Objective High Spatial Resolution Soil Moisture Index

    Science.gov (United States)

    Zavodsky, B.; Case, J.; White, K.; Bell, J. R.

    2015-12-01

    Drought detection, analysis, and mitigation has become a key challenge for a diverse set of decision makers, including but not limited to operational weather forecasters, climatologists, agricultural interests, and water resource management. One tool that is heavily used is the United States Drought Monitor (USDM), which is derived from a complex blend of objective data and subjective analysis on a state-by-state basis using a variety of modeled and observed precipitation, soil moisture, hydrologic, and vegetation and crop health data. The NASA Short-term Prediction Research and Transition (SPoRT) Center currently runs a real-time configuration of the Noah land surface model (LSM) within the NASA Land Information System (LIS) framework. The LIS-Noah is run at 3-km resolution for local numerical weather prediction (NWP) and situational awareness applications at select NOAA/National Weather Service (NWS) forecast offices over the Continental U.S. (CONUS). To enhance the practicality of the LIS-Noah output for drought monitoring and assessing flood potential, a 30+-year soil moisture climatology has been developed in an attempt to place near real-time soil moisture values in historical context at county- and/or watershed-scale resolutions. This LIS-Noah soil moisture climatology and accompanying anomalies is intended to complement the current suite of operational products, such as the North American Land Data Assimilation System phase 2 (NLDAS-2), which are generated on a coarser-resolution grid that may not capture localized, yet important soil moisture features. Daily soil moisture histograms are used to identify the real-time soil moisture percentiles at each grid point according to the county or watershed in which the grid point resides. Spatial plots are then produced that map the percentiles as proxies to the different USDM categories. This presentation will highlight recent developments of this gridded, objective soil moisture index, comparison to subjective

  7. Precision glass molding of high-resolution diffractive optical elements

    Science.gov (United States)

    Prater, Karin; Dukwen, Julia; Scharf, Toralf; Herzig, Hans P.; Plöger, Sven; Hermerschmidt, Andreas

    2016-04-01

    The demand of high resolution diffractive optical elements (DOE) is growing. Smaller critical dimensions allow higher deflection angles and can fulfill more demanding requirements, which can only be met by using electron-beam lithography. Replication techniques are more economical, since the high cost of the master can be distributed among a larger number of replicas. The lack of a suitable mold material for precision glass molding has so far prevented an industrial use. Glassy Carbon (GC) offers a high mechanical strength and high thermal strength. No anti-adhesion coatings are required in molding processes. This is clearly an advantage for high resolution, high aspect ratio microstructures, where a coating with a thickness between 10 nm and 200 nm would cause a noticeable rounding of the features. Electron-beam lithography was used to fabricate GC molds with highest precision and feature sizes from 250 nm to 2 μm. The master stamps were used for precision glass molding of a low Tg glass L-BAL42 from OHARA. The profile of the replicated glass is compared to the mold with the help of SEM images. This allows discussion of the max. aspect-ratio and min. feature size. To characterize optical performances, beamsplitting elements are fabricated and their characteristics were investigated, which are in excellent agreement to theory.

  8. Characterization of high-current, high-temperature superconductor current lead elements

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, R.C.; Evans, D.J.; Fisher, B.L. [Argonne National Lab., IL (United States); Brockenborough, W.E.; Roberts, P.R.; Rodenbush, A.J. [American Superconductor Corp., Westborough, MA (United States)

    1996-08-01

    The refrigeration loads of current leads for superconducting magnets can be significantly reduced by using high-temperature superconductor (HTS) leads. An HTS conductor type that is well suited for this application is a laminated sintered stack of HTS powder-in-tube (PIT) tapes. The superconducting elements are normally characterized by their manufacturer by measuring critical currents at 77 K in self field. Additional characterization, which correlates electrical performance at 77 K and at lower temperatures with applied magnetic fields, provides the current lead designer and conductor element manufacturer with critical information. For HTS conductor elements comprising a laminated and sintered stack of Bi-2223 PIT tapes having an alloyed Ag sheath, this characterization uses variable applied fields and operating temperatures.

  9. Nanowires for high DC current applications

    Energy Technology Data Exchange (ETDEWEB)

    Hankemeier, Sebastian; Sachse, Konrad; Stark, Yuliya; Scholz, Matthias; Hoffmann, Germar; Froemter, Robert; Oepen, Hans Peter [Universitaet Hamburg (Germany)

    2008-07-01

    For a more detailed investigation of current induced domain wall movement in nanowires by spin torque effect, it is essential to have maximum control of the external experimental parameters, i.e. the current density and the wire temperature. Additional, to study the forces that act on the walls, it is desirable to perform experiments with DC currents large enough to move the domain walls. In this talk we present the realization of Permalloy nanowires which sustain current densities larger 4.10{sup 12} A/m{sup 2}. The wires are made from 20 nm thick Permalloy, evaporated on diamond, with a width of 1 {mu}m and a length of 25 {mu}m. While applying current densities beyond 10{sup 11} A/m{sup 2}, we observe ohmic heating of the wires, which causes annealing effects. This effect can be used to improve the specific resistance of the wire near to the values of bulk material. The experiments are performed under HV conditions to prevent oxidation and cooling with liquid nitrogen is necessary for heat dissipation. The temperature of the wire, which depends on the applied current, has been evaluated utilizing the change in wire-resistance and estimated by heat transfer calculations.

  10. Calibration of a High Resolution Airborne 3-D SAR

    DEFF Research Database (Denmark)

    Dall, Jørgen; Grinder-Pedersen, Jan; Madsen, S.N.

    1997-01-01

    (EMI). In order to achieve a high geodetic fidelity when using such systems operationally, calibration procedures must be applied. Inaccurate navigation data and system parameters as well as system imperfections must be accounted for. This paper presents theoretical models describing the impact of key......The potential of across-track interferometric (XTI) synthetic aperture radar (SAR) for producing high resolution 3D imagery has been demonstrated by several airborne systems including EMISAR, the dual frequency, polarimetric, and interferometric SAR developed at the Dept. of Electromagnetic Systems...

  11. Coverage Options for a Low cost, High Resolution Optical Constellation

    OpenAIRE

    Price, M E; Levett, W.; Graham, K.

    2003-01-01

    This paper presents the range of coverage options available to TopSat like small satellites, both singly and in a small constellation. TopSat is a low-cost, high resolution and image quality, optical small satellite, due for launch in October 2004. In particular, the paper considers the use of tuned, repeat ground track orbits to improve coverage for selected ground targets, at the expense of global coverage. TopSat is designed to demonstrate the capabilities of small satellites for high valu...

  12. High resolution study of magnetic ordering at absolute zero.

    Science.gov (United States)

    Lee, M; Husmann, A; Rosenbaum, T F; Aeppli, G

    2004-05-07

    High resolution pressure measurements in the zero-temperature limit provide a unique opportunity to study the behavior of strongly interacting, itinerant electrons with coupled spin and charge degrees of freedom. Approaching the precision that has become the hallmark of experiments on classical critical phenomena, we characterize the quantum critical behavior of the model, elemental antiferromagnet chromium, lightly doped with vanadium. We resolve the sharp doubling of the Hall coefficient at the quantum critical point and trace the dominating effects of quantum fluctuations up to surprisingly high temperatures.

  13. High-resolution protein structure determination by serial femtosecond crystallography.

    Science.gov (United States)

    Boutet, Sébastien; Lomb, Lukas; Williams, Garth J; Barends, Thomas R M; Aquila, Andrew; Doak, R Bruce; Weierstall, Uwe; DePonte, Daniel P; Steinbrener, Jan; Shoeman, Robert L; Messerschmidt, Marc; Barty, Anton; White, Thomas A; Kassemeyer, Stephan; Kirian, Richard A; Seibert, M Marvin; Montanez, Paul A; Kenney, Chris; Herbst, Ryan; Hart, Philip; Pines, Jack; Haller, Gunther; Gruner, Sol M; Philipp, Hugh T; Tate, Mark W; Hromalik, Marianne; Koerner, Lucas J; van Bakel, Niels; Morse, John; Ghonsalves, Wilfred; Arnlund, David; Bogan, Michael J; Caleman, Carl; Fromme, Raimund; Hampton, Christina Y; Hunter, Mark S; Johansson, Linda C; Katona, Gergely; Kupitz, Christopher; Liang, Mengning; Martin, Andrew V; Nass, Karol; Redecke, Lars; Stellato, Francesco; Timneanu, Nicusor; Wang, Dingjie; Zatsepin, Nadia A; Schafer, Donald; Defever, James; Neutze, Richard; Fromme, Petra; Spence, John C H; Chapman, Henry N; Schlichting, Ilme

    2012-07-20

    Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 micrometer by 1 micrometer by 3 micrometers) of the well-characterized model protein lysozyme. The agreement with synchrotron data demonstrates the immediate relevance of SFX for analyzing the structure of the large group of difficult-to-crystallize molecules.

  14. High resolution upgrade of the ATF damping ring BPM system

    Energy Technology Data Exchange (ETDEWEB)

    Terunuma, N.; Urakawa, J.; /KEK, Tsukuba; Frisch, J.; May, J.; McCormick, D.; Nelson, J.; Seryi, A.; Smith, T.; Woodley, M.; /SLAC; Briegel, C.; Dysert, R.; /Fermilab

    2008-05-01

    A beam position monitor (BPM) upgrade at the KEK Accelerator Test Facility (ATF) damping ring has been accomplished in its first stage, carried out by a KEK/FNAL/SLAC collaboration under the umbrella of the global ILC R&D effort. The upgrade consists of a high resolution, high reproducibility read-out system, based on analog and digital downconversion techniques, digital signal processing, and also tests a new automatic gain error correction schema. The technical concept and realization, as well as preliminary results of beam studies are presented.

  15. Localized corrosion information using high resolution measurement devices

    DEFF Research Database (Denmark)

    Ambat, Rajan

    2005-01-01

    to control the solution flow at the tip. Through addition of reference and counter electrodes, the pipette system becomes a microscopic electrochemical cell, which can then be used with high precision to determine the electrochemical characteristics of the microstructural region of interest. The capability...... of the technique could be further enhanced by adding new features such as high resolution video visualization systems, fretting/tribo-corroson attachments, and also by integrating it with stress corrosion testing, corrosion investigation of concrete for a few to name with. The corrosion group in MPT, Technical...

  16. Radiation length imaging with high-resolution telescopes

    Science.gov (United States)

    Stolzenberg, U.; Frey, A.; Schwenker, B.; Wieduwilt, P.; Marinas, C.; Lütticke, F.

    2017-02-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length X/X0 profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D images of the radiation length of thin planar objects. At the heart of the X/X0 imaging is a spatially resolved measurement of the scattering angles of particles traversing the object under study. The main challenges are the alignment of the reference telescope and the calibration of its angular resolution. In order to demonstrate the capabilities of X/X0 imaging, a test beam experiment has been conducted. The devices under test were two mechanical prototype modules of the Belle II vertex detector. A data sample of 100 million tracks at 4 GeV has been collected, which is sufficient to resolve complex material profiles on the 30 μm scale.

  17. Spatial-temperature high resolution map for early cancer diagnosis

    Science.gov (United States)

    Gavriloaia, Gheorghe V.; Hurduc, Anca; Ghimigean, Ana-Maria; Fumarel, Radu

    2009-02-01

    Heat is one of the most important parameters of living beings. Skin temperature is not the same on the entire body and so, a thermal signature can be got. Infrared map on serial imaging can constitute an early sign of an abnormality. Thermography detects changes in tissue that appear before and accompany many diseases including cancer. As this map has a better resolution an early cancer diagnosis can be done. The temperature of neoplasic tissue is different up to 1.5 °C than that of the healthy tissue as a result of the specific metabolic rate. The infrared camera images show very quickly the heat transferred by radiation. A lot of factors disturb the temperature conversion to pixel intensity. A sensitive temperature sensor with a 10 Mpixels video camera, showing its spatial position, and a computer fusion program were used for the map with high spatial-temperature resolution. A couple of minutes are necessary to get a high resolution map. The asymmetry and borders were the main parameters analyzed. The right cancer diagnosis was for about 78.4% of patients with thyroid cancer, and more than 89.6% from patients with breast cancer. In the near future, the medical prognosis will be improved by fractal analysis.

  18. Diagnosis of Type-I hiatal hernia: a comparison of high-resolution manometry and endoscopy.

    Science.gov (United States)

    Khajanchee, Y S; Cassera, M A; Swanström, L L; Dunst, C M

    2013-01-01

    Sliding Type-I hiatal hernia is commonly diagnosed using upper endoscopy, barium swallow or less commonly, esophageal manometry. Current data suggest that endoscopy is superior to barium swallow or esophageal manometry. Recently, high-resolution manometry has become available for the assessment of esophageal motility. This novel technology is capable of displaying spatial and topographic pressure profiles of gastroesophageal junction and crural diaphragm in real time. The objective of the current study was to compare the specificity and sensitivity of high-resolution manometry and endoscopy in the diagnosis of sliding hiatal hernia in patients with gastroesophageal reflux disease. Data were analyzed retrospectively for 83 consecutive patients (61% females, mean age 52 ± 13.2 years) with objective gastroesophageal reflux disease who were considered for laparoscopic antireflux surgery between January 2006 and January 2009 and had preoperative high-resolution manometry and endoscopy. Manometrically, hiatal hernia was defined as separation of the gastroesophageal junction >2.0 cm from the crural diaphragm. Intraoperative diagnosis of hiatal hernia was used as the gold standard. Sensitivity, specificity and likelihood ratios of a positive test and a negative test were used to compare the performance of the two diagnostic modalities. Forty-two patients were found to have a Type-I sliding hiatal hernia (>2 cm) during surgery. Twenty-two patients had manometric criteria for a hiatal hernia by high-resolution manometry, and 36 patients were described as having a hiatal hernia by preoperative endoscopy. False positive results were significantly fewer (higher specificity) with high-resolution manometry as compared with endoscopy (4.88% vs. 31.71%, P= 0.01). There were no significant differences in the false negative results (sensitivity) between the two diagnostic modalities (47.62% vs. 45.24%, P= 0.62). Analysis of likelihood ratios of a positive and negative test

  19. Lipid and Glycolipid Isomer Analyses Using Ultra-High Resolution Ion Mobility Spectrometry Separations

    Energy Technology Data Exchange (ETDEWEB)

    Wojcik, Roza; Webb, Ian; Deng, Liulin; Garimella, Sandilya; Prost, Spencer; Ibrahim, Yehia; Baker, Erin; Smith, Richard

    2017-01-01

    Understanding the biological mechanisms related to lipids and glycolipids is challenging due to the vast number of possible isomers. Mass spectrometry (MS) measurements are currently the dominant approach for studying and providing detailed information on lipid and glycolipid structures. However, difficulties in distinguishing many structural isomers (e.g. distinct acyl chain positions, double bond locations, as well as glycan isomers) inhibit the understanding of their biological roles. Here we utilized ultra-high resolution ion mobility spectrometry (IMS) separations based upon the use of traveling waves in a serpentine long path length multi-pass Structures for Lossless Manipulations (SLIM) to enhance isomer resolution. The multi-pass arrangement allowed separations ranging from ~16 m (1 pass) to ~470 m (32 passes) to be investigated for the distinction of lipids and glycolipids with extremely small structural differences. These ultra-high resolution SLIM IMS-MS analyses provide a foundation for exploring and better understanding isomer specific biological and disease processes.

  20. High-resolution MR imaging of the cutis and subcutis. Histological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Krug, B.; Kugel, H.; Krahe, T.; Lackner, K. [Koeln Univ. (Germany). Radiologisches Inst. und Poliklinik; Schulze, H.J. [Koeln Univ. (Germany). Klinik und Poliklinik fuer Dermatologie und Venerologie; Gieseke, J. [Philips Medical Systems, Hamburg (Germany)

    1998-09-01

    Objective: To determine whether the spatial resolution that can be achieved with currently available MR devices is adequate for the evaluation of skin disease. Material and Methods: We correlated high-resolution MR images of the skin with dermatohistopathology in 26 patients. The examinations were carried out on a 1.0 T imager using a commercially available surface coil (ID 7.5 cm) and optimized SE and GE sequences. Image quality was assessed by four readers on a questionnaire. Results: The visualization of the dermis, subcutaneous tissue, and muscle fascia allowed a pattern analysis that gave findings identical to those at dermatohistopathology. It was possible to distinguish septal from lobular panniculitis, and lipatrophia from sclerodermia. Images with contrast media infusion were useful in the differential diagnosis. Conclusion: High-resolution MR imaging may narrow down the differential diagnosis of various skin diseases and may help to reduce the number of skin biopsies on certain indications. (orig.)

  1. High-resolution photocurrent microscopy using near-field cathodoluminescence of quantum dots

    Directory of Open Access Journals (Sweden)

    Heayoung P. Yoon

    2013-06-01

    Full Text Available We report a fast, versatile photocurrent imaging technique to visualize the local photo response of solar energy devices and optoelectronics using near-field cathodoluminescence (CL from a homogeneous quantum dot layer. This approach is quantitatively compared with direct measurements of high-resolution Electron Beam Induced Current (EBIC using a thin film solar cell (n-CdS / p-CdTe. Qualitatively, the observed image contrast is similar, showing strong enhancement of the carrier collection efficiency at the p-n junction and near the grain boundaries. The spatial resolution of the new technique, termed Q-EBIC (EBIC using quantum dots, is determined by the absorption depth of photons. The results demonstrate a new method for high-resolution, sub-wavelength photocurrent imaging measurement relevant for a wide range of applications.

  2. Label-free imaging of cellular malformation using high resolution photoacoustic microscopy

    Science.gov (United States)

    Chen, Zhongjiang; Li, Bingbing; Yang, Sihua

    2014-09-01

    A label-free high resolution photoacoustic microscopy (PAM) system for imaging cellular malformation is presented. The carbon fibers were used to testify the lateral resolution of the PAM. Currently, the lateral resolution is better than 2.7 μm. The human normal red blood cells (RBCs) were used to prove the imaging capability of the system, and a single red blood cell was mapped with high contrast. Moreover, the iron deficiency anemia RBCs were clearly distinguished from the cell morphology by using the PAM. The experimental results demonstrate that the photoacoustic microscopy system can accomplish label-free photoacoustic imaging and that it has clinical potential for use in the detection of erythrocytes and blood vessels malformation.

  3. Polystyrene negative resist for high-resolution electron beam lithography

    Directory of Open Access Journals (Sweden)

    Ma Siqi

    2011-01-01

    Full Text Available Abstract We studied the exposure behavior of low molecular weight polystyrene as a negative tone electron beam lithography (EBL resist, with the goal of finding the ultimate achievable resolution. It demonstrated fairly well-defined patterning of a 20-nm period line array and a 15-nm period dot array, which are the densest patterns ever achieved using organic EBL resists. Such dense patterns can be achieved both at 20 and 5 keV beam energies using different developers. In addition to its ultra-high resolution capability, polystyrene is a simple and low-cost resist with easy process control and practically unlimited shelf life. It is also considerably more resistant to dry etching than PMMA. With a low sensitivity, it would find applications where negative resist is desired and throughput is not a major concern.

  4. A new matching algorithm for high resolution mass spectra

    DEFF Research Database (Denmark)

    Hansen, Michael Edberg; Smedsgaard, Jørn

    2004-01-01

    We present a new matching algorithm designed to compare high-resolution spectra. Whereas existing methods are bound to compare fixed intervals of ion masses, the accurate mass spectrum (AMS) distance method presented here is independent of any alignment. Based on the Jeffreys-Matusitas (JM......) distance, a difference between observed peaks across pairs of spectra can be calculated, and used to find a unique correspondence between the peaks. The method takes into account that there may be differences in resolution of the spectra. The algorithm is used for indexing in a database containing 80...... accurate mass spectra from an analysis of extracts of 80 isolates representing the nine closely related species in the Penicillium series Viridicata. Using this algorithm we can obtain a retrieval performance of approximate to97-98% that is comparable with the best of the existing methods (e.g., the dot...

  5. Observations of solar scattering polarization at high spatial resolution

    CERN Document Server

    Snik, F; Ichimoto, K; Fischer, C E; Keller, C U; Lites, B W

    2010-01-01

    The weak, turbulent magnetic fields that supposedly permeate most of the solar photosphere are difficult to observe, because the Zeeman effect is virtually blind to them. The Hanle effect, acting on the scattering polarization in suitable lines, can in principle be used as a diagnostic for these fields. However, the prediction that the majority of the weak, turbulent field resides in intergranular lanes also poses significant challenges to scattering polarization observations because high spatial resolution is usually difficult to attain. We aim to measure the difference in scattering polarization between granules and intergranules. We present the respective center-to-limb variations, which may serve as input for future models. We perform full Stokes filter polarimetry at different solar limb positions with the CN band filter of the Hinode-SOT Broadband Filter Imager, which represents the first scattering polarization observations with sufficient spatial resolution to discern the granulation. Hinode-SOT offer...

  6. High resolution ultrasound and photoacoustic imaging of single cells.

    Science.gov (United States)

    Strohm, Eric M; Moore, Michael J; Kolios, Michael C

    2016-03-01

    High resolution ultrasound and photoacoustic images of stained neutrophils, lymphocytes and monocytes from a blood smear were acquired using a combined acoustic/photoacoustic microscope. Photoacoustic images were created using a pulsed 532 nm laser that was coupled to a single mode fiber to produce output wavelengths from 532 nm to 620 nm via stimulated Raman scattering. The excitation wavelength was selected using optical filters and focused onto the sample using a 20× objective. A 1000 MHz transducer was co-aligned with the laser spot and used for ultrasound and photoacoustic images, enabling micrometer resolution with both modalities. The different cell types could be easily identified due to variations in contrast within the acoustic and photoacoustic images. This technique provides a new way of probing leukocyte structure with potential applications towards detecting cellular abnormalities and diseased cells at the single cell level.

  7. High resolution ultrasound and photoacoustic imaging of single cells

    Directory of Open Access Journals (Sweden)

    Eric M. Strohm

    2016-03-01

    Full Text Available High resolution ultrasound and photoacoustic images of stained neutrophils, lymphocytes and monocytes from a blood smear were acquired using a combined acoustic/photoacoustic microscope. Photoacoustic images were created using a pulsed 532 nm laser that was coupled to a single mode fiber to produce output wavelengths from 532 nm to 620 nm via stimulated Raman scattering. The excitation wavelength was selected using optical filters and focused onto the sample using a 20× objective. A 1000 MHz transducer was co-aligned with the laser spot and used for ultrasound and photoacoustic images, enabling micrometer resolution with both modalities. The different cell types could be easily identified due to variations in contrast within the acoustic and photoacoustic images. This technique provides a new way of probing leukocyte structure with potential applications towards detecting cellular abnormalities and diseased cells at the single cell level.

  8. High-resolution proper motions in a sunspot penumbra

    CERN Document Server

    Márquez, I; Bonet, J A

    2006-01-01

    Local correlation tracking techniques are used to measure proper motions in a series of high angular resolution (~0.1 arcsec) penumbra images. If these motions trace true plasma motions, then we have detected converging flows that arrange the plasma in long narrow filaments co-spatial with dark penumbral filaments. Assuming that these flows are stationary, the vertical stratification of the atmosphere and the conservation of mass suggest downflows in the filaments of the order of 200 m/s. The association between downflows and dark features may be a sign of convection, as it happens with the non-magnetic granulation. Insufficient spatial resolution may explain why the estimated vertical velocities are not fast enough to supply the radiative losses of penumbrae.

  9. Microcalorimetry for High-Resolution X-Ray Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, Stephen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-01-03

    Magnetic Microcalorimeters (MMCs) are gamma-ray detectors with an energy resolution 10x higher than high-purity germanium detectors. They can increase the accuracy of non-destructive analysis of nuclear materials, enable the detection of new isotopes (e.g. Pu-242 of U-236), and improve nuclear data in cases where Ge detectors are limited by line overlap. MMCs consist of a magnetic sensor operated at temperatures below 50 mK, and they infer gamma-ray energies from the change in magnetization due to the temperature increase after gamma-ray absorption. The goal of this project is to further increase the energy resolution and sensitivity of MMC gamma detectors.

  10. High-resolution NMR imaging of the hand

    Energy Technology Data Exchange (ETDEWEB)

    Koenig, H.; Lucas, D.

    1986-12-01

    With high spatial resolution guaranteed, NMR imaging allows to simultaneously make visible the complex osseous, chondral, and ligamentous structures of the hand. The examinations reported on were made with a 1.0 Tesla Magnetom using a special surface coil so as to achieve cut heights of 3-4 mm and an in-plane resolution of 0.5 mm. In addition to normal test persons, 29 patients were examined who had pseudoarthrosis of the os naviculare, lunatomalacia, rheumatic arthritis, or bone and soft-tissue tumors. Comparison with X-ray radiography or bone scintiscans showed that NMR imaging is capable of demonstrating localisation and extension of bone marrow or bone joint abnormalities at an earlier stage.

  11. High-resolution friction force microscopy under electrochemical control

    Science.gov (United States)

    Labuda, Aleksander; Paul, William; Pietrobon, Brendan; Lennox, R. Bruce; Grütter, Peter H.; Bennewitz, Roland

    2010-08-01

    We report the design and development of a friction force microscope for high-resolution studies in electrochemical environments. The design choices are motivated by the experimental requirements of atomic-scale friction measurements in liquids. The noise of the system is analyzed based on a methodology for the quantification of all the noise sources. The quantitative contribution of each noise source is analyzed in a series of lateral force measurements. Normal force detection is demonstrated in a study of the solvation potential in a confined liquid, octamethylcyclotetrasiloxane. The limitations of the timing resolution of the instrument are discussed in the context of an atomic stick-slip measurement. The instrument is capable of studying the atomic friction contrast between a bare Au(111) surface and a copper monolayer deposited at underpotential conditions in perchloric acid.

  12. High-resolution multiphoton imaging of tumors in vivo.

    Science.gov (United States)

    Wyckoff, Jeffrey; Gligorijevic, Bojana; Entenberg, David; Segall, Jeffrey; Condeelis, John

    2011-10-01

    Analysis of the individual steps in metastasis is crucial if insights at the molecular level are to be linked to the cell biology of cancer. A technical hurdle to achieving the analysis of the individual steps of metastasis is the fact that, at the gross level, tumors are heterogeneous in both animal models and patients. Human primary tumors show extensive variation in all properties ranging from growth and morphology of the tumor through tumor-cell density in the blood and formation and growth of metastases. Methods capable of the direct visualization and analysis of tumor-cell behavior at single-cell resolution in vivo have become crucial in advancing the understanding of mechanisms of metastasis, the definition of microenvironment, and the markers related to both. This article discusses the use of high-resolution multiphoton imaging of tumors (specifically breast tumors in mice) in vivo.

  13. High spatial resolution soft-x-ray microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Meyer-Ilse, W.; Medecki, H.; Brown, J.T. [Ernest Orlando Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    A new soft x-ray microscope (XM-1) with high spatial resolution has been constructed by the Center for X-ray Optics. It uses bending magnet radiation from beamline 6.1 at the Advanced Light Source, and is used in a variety of projects and applications in the life and physical sciences. Most of these projects are ongoing. The instrument uses zone plate lenses and achieves a resolution of 43 nm, measured over 10% to 90% intensity with a knife edge test sample. X-ray microscopy permits the imaging of relatively thick samples, up to 10 {mu}m thick, in water. XM-1 has an easy to use interface, that utilizes visible light microscopy to precisely position and focus the specimen. The authors describe applications of this device in the biological sciences, as well as in studying industrial applications including structured polymer samples.

  14. Range ambiguity resolution for high PRF pulse-Doppler radar

    Science.gov (United States)

    Postema, G. B.

    The range ambiguity resolution for high 'PRF pulse-Doppler radars can be resolved using a simple algorithm based on residue arithmetic. The unambiguous range is found from R = T + R(a), where T is the output of a look-up table and R(a) is one of the measured ambiguous ranges. This formula is easily extended to multiple PRF ranging systems, where three or more measurements are required for the ambiguity resolution. Target obscuration in clutter reduces the visibility and leads, especially in dense target environments, to ghost ranges. It is shown that long range coverage requires a small resolved pulse length and PRFs as low as practical in the intended clutter and target environment. Special attention is given to the generation of sparsely populated look-up tables that reduce the ghosting problem. A practical example for an S-band surveillance radar is presented.

  15. High-Resolution Characterization of UMo Alloy Microstructure

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kovarik, Libor [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Joshi, Vineet V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jana, Saumyadeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Manandhar, Sandeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Arey, Bruce W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lavender, Curt A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-11-30

    This report highlights the capabilities and procedure for high-resolution characterization of UMo fuels in PNNL. Uranium-molybdenum (UMo) fuel processing steps, from casting to forming final fuel, directly affect the microstructure of the fuel, which in turn dictates the in-reactor performance of the fuel under irradiation. In order to understand the influence of processing on UMo microstructure, microstructure characterization techniques are necessary. Higher-resolution characterization techniques like transmission electron microscopy (TEM) and atom probe tomography (APT) are needed to interrogate the details of the microstructure. The findings from TEM and APT are also directly beneficial for developing predictive multiscale modeling tools that can predict the microstructure as a function of process parameters. This report provides background on focused-ion-beam–based TEM and APT sample preparation, TEM and APT analysis procedures, and the unique information achievable through such advanced characterization capabilities for UMo fuels, from a fuel fabrication capability viewpoint.

  16. High-Resolution, Wide-Field-of-View Scanning Telescope

    Science.gov (United States)

    Sepulveda, Cesar; Wilson, Robert; Seshadri, Suresh

    2007-01-01

    A proposed telescope would afford high resolution over a narrow field of view (<0.10 ) while scanning over a total field of view nominally 16 wide without need to slew the entire massive telescope structure. The telescope design enables resolution of a 1-m-wide object in a 50- km-wide area of the surface of the Earth as part of a 200-km-wide area field of view monitored from an orbit at an altitude of 700 km. The conceptual design of this telescope could also be adapted to other applications both terrestrial and extraterrestrial in which there are requirements for telescopes that afford both wide- and narrow-field capabilities. In the proposed telescope, the scanning would be effected according to a principle similar to that of the Arecibo radio telescope, in which the primary mirror is stationary with respect to the ground and a receiver is moved across the focal surface of the primary mirror. The proposed telescope would comprise (1) a large spherical primary mirror that would afford high resolution over a narrow field of view and (2) a small displaceable optical relay segment that would be pivoted about the center of an aperture stop to effect the required scanning (see figure). Taken together, both comprise a scanning narrow-angle telescope that does not require slewing the telescope structure. In normal operation, the massive telescope structure would stare at a fixed location on the ground. The inner moveable relay optic would be pivoted to scan the narrower field of view over the wider one, making it possible to retain a fixed telescope orientation, while obtaining high-resolution images over multiple target areas during an interval of 3 to 4 minutes in the intended orbit. The pivoting relay segment of the narrow-angle telescope would include refractive and reflective optical elements, including two aspherical mirrors, to counteract the spherical aberration of the primary mirror. Overall, the combination of the primary mirror and the smaller relay optic

  17. High Resolution Infrared Spectroscopy of Allene -D4.

    Science.gov (United States)

    Rousan, Khetam Ibrahim Khasawinah

    Two parallel bands of allene-d(,4), (nu)(,6) (occurring at 1920.2289 cm('-1)) and (nu)(,5) (occurring at 2228.4133 cm('-1)), and the perpendicular band, (nu)(,8) (occurring at 2321.2484 cm('-1)), were recorded by using two spectrometers under high resolution. The combination band, (nu)(,2) + (nu)(,7), was measured also; the band origin is located at 2276.0053 cm('-1), rather distant from the previously reported one at 2267.0 cm('-1). Initially, by using the 4.5 m grating spectrometer, deconvolution of the spectra achieved a resolution of (TURN)0.007 cm('-1). Although the resolution was high, a detailed analysis of the K structure could not be obtained. Other measurements were carried out by using a BOMEM Fourier transform spectrometer. Deconvolution of the spectra achieved a resolution of (TURN)0.002 cm(' -1). This made it possible to resolve and analyze these bands in detail. Successful ground state and upper state analyses were completed from this data. Combining all the three bands together, a ground state analysis has resulted in better values of. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI). than the previously published works on the same molecule by others. A set of accurate spectroscopic constants was obtained for each band. The spectrum of the (nu)(,8) band was analyzed in detail, including the perturbations. The perturbed states for (nu)(,8) were assigned as 2(nu)(,9) + (nu)(,10), (nu)(,2) + (nu)(,9) + (nu)(,11) and 2(nu)(,3) + (nu)(,4), and the spectroscopic constants for those perturbed states were calculated.

  18. Current-voltage curve of a bipolar membrane at high current density

    NARCIS (Netherlands)

    Aritomi, T.; Boomgaard, van den Th.; Strathmann, H.

    1996-01-01

    The potential drop across a bipolar membrane was measured as a function of the applied current density. As a result, an inflection point was observed in the obtained current-voltage curve at high current density. This inflection point indicates that at high current densities water supply from outsid

  19. Current-voltage curve of a bipolar membrane at high current density

    NARCIS (Netherlands)

    Aritomi, T.; van den Boomgaard, Anthonie; Strathmann, H.

    1996-01-01

    The potential drop across a bipolar membrane was measured as a function of the applied current density. As a result, an inflection point was observed in the obtained current-voltage curve at high current density. This inflection point indicates that at high current densities water supply from

  20. Development of high temperature superconductors having high critical current density

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Gye Wong; Kim, C. J.; Lee, H.G.; Kwon, S. C.; Lee, H. J.; Kim, K. B.; Park, J. Y.; Jung, C. H

    2000-08-01

    Fabrication of high T{sub c} superconductors and its applications for electric power device were carried out for developing superconductor application technologies. High quality YBCO superconductors was fabricated by melt texture growth, top-seeded melt growth process and multi-seeded melt growth process and the properties was compared. The critical current density of the melt processed YBCO superconductors was about few 10,000 A/cm{sup 2} and the levitation force was 50 N. The processing time needed for the growth of the 123 single grain was greatly reduced by applying multi-seeding without no significant degradation of the levitation force. The multi-seeded melt growth process was confirmed as a time-saving and cost-effective method for the fabrication of bulk superconductors with controlled crystallographic orientation.