WorldWideScience

Sample records for current experimental design

  1. Experimental Verification of Current Shear Design Equations for HSRC Beams

    Directory of Open Access Journals (Sweden)

    Attaullah Shah

    2012-07-01

    Full Text Available Experimental research on the shear capacity of HSRC (High Strength Reinforced Concrete beams is relatively very limited as compared to the NSRC (Normal Strength Reinforced Concrete beams. Most of the Building Codes determine the shear strength of HSRC with the help of empirical equations based on experimental work of NSRC beams and hence these equations are generally regarded as un-conservative for HSRC beams particularly at low level of longitudinal reinforcement. In this paper, 42 beams have been tested in two sets, such that in 21 beams no transverse reinforcement has been used, whereas in the remaining 21 beams, minimum transverse reinforcement has been used as per ACI-318 (American Concrete Institute provisions. Two values of compressive strength 52 and 61 MPa, three values of longitudinal steel ratio and seven values of shear span to depth ratio have been have been used. The beams were tested under concentrated load at the mid span. The results are compared with the equations proposed by different international building codes like ACI, AASHTO LRFD, EC (Euro Code, Canadian Code and Japanese Code for shear strength of HSRC beams.From comparison, it has been observed that some codes are less conservative for shear design of HSRC beams and further research is required to rationalize these equations.

  2. Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

    Science.gov (United States)

    Smith, Justin D.

    2012-01-01

    This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have…

  3. Single-Case Experimental Design: Current Standards and Applications in Occupational Therapy.

    Science.gov (United States)

    Lane, Justin D; Ledford, Jennifer R; Gast, David L

    Occupational therapy is a field with a long-standing history of recommending and implementing interventions designed to improve the quality of life of clients with disabilities. Often, the interventions are individualized to meet the needs of this diverse group of clients in dynamic settings. Identifying effective and efficient interventions for such a diverse group of clients and settings requires a flexible research approach. Single-case experimental designs (SCEDs) allow practitioners and researchers to answer experimental questions within the context of rigorous research designs. The purpose of this article is to highlight the similarities between the mission of occupational therapy and SCEDs. Recommendations for designing single-case studies with the framework provided by the Single-Case Reporting Guideline in Behavioral Interventions are provided. In addition, common problems and proposed solutions, along with implications for practitioners and researchers, are provided. Copyright © 2017 by the American Occupational Therapy Association, Inc.

  4. Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

    Science.gov (United States)

    Smith, Justin D.

    2013-01-01

    This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have precluded widespread implementation and acceptance of the SCED as a viable complementary methodology to the predominant group design. This article includes a description of the research design, measurement, and analysis domains distinctive to the SCED; a discussion of the results within the framework of contemporary standards and guidelines in the field; and a presentation of updated benchmarks for key characteristics (e.g., baseline sampling, method of analysis), and overall, it provides researchers and reviewers with a resource for conducting and evaluating SCED research. The results of the systematic review of 409 studies suggest that recently published SCED research is largely in accordance with contemporary criteria for experimental quality. Analytic method emerged as an area of discord. Comparison of the findings of this review with historical estimates of the use of statistical analysis indicates an upward trend, but visual analysis remains the most common analytic method and also garners the most support amongst those entities providing SCED standards. Although consensus exists along key dimensions of single-case research design and researchers appear to be practicing within these parameters, there remains a need for further evaluation of assessment and sampling techniques and data analytic methods. PMID:22845874

  5. Experimental design

    Science.gov (United States)

    Lim, H. S.

    1983-01-01

    The design of long life, low weight nickel cadmium cells is studied. The status of a program to optimize nickel electrodes for the best performance is discussed. The pore size of the plaque, the mechanical strength and active material loading are considered in depth.

  6. Experimental Design Research

    DEFF Research Database (Denmark)

    of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology......This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations......, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current...

  7. Numerical and experimental investigation on the performance of three newly designed 100 kW-class tidal current turbines

    Directory of Open Access Journals (Sweden)

    Museok Song

    2012-09-01

    Full Text Available Three types of 100 kW-class tidal stream turbines are proposed and their performance is studied both numerically and experimentally. Following a wind turbine design procedure, a base blade is derived and two additional blades are newly designed focusing more on efficiency and cavitation. For the three designed turbines, a CFD is performed by using FLUENT. The calculations predict that the newly designed turbines perform better than the base turbine and the tip vortex can be reduced with additional efficiency increase by adopting a tip rake. The performance of the turbines is tested in a towing tank with 700 mm models. The scale problem is carefully investigated and the measurements are compared with the CFD results. All the prediction from the CFD is supported by the model experiment with some quantitative discrepancy. The maximum efficiencies are 0.49 (CFD and 0.45 (experiment at TSR 5.17 for the turbine with a tip rake.

  8. Design and Experimental Study of a Current Transformer with a Stacked PCB Based on B-Dot.

    Science.gov (United States)

    Wang, Jingang; Si, Diancheng; Tian, Tian; Ren, Ran

    2017-04-10

    An electronic current transformer with a B-dot sensor is proposed in this study. The B-dot sensor can realize the current measurement of the transmission line in a non-contact way in accordance with the principle of magnetic field coupling. The multiple electrodes series-opposing structure is applied together with differential input structures and active integrating circuits, which can allow the sensor to operate in differential mode. Maxwell software is adopted to model and simulate the sensor. Optimization of the sensor structural parameters is conducted through finite-element simulation. A test platform is built to conduct the steady-state characteristic, on-off operation, and linearity tests for the designed current transformer under the power-frequency current. As shown by the test results, in contrast with traditional electromagnetic CT, the designed current transformer can achieve high accuracy and good phase-frequency; its linearity is also very good at different distances from the wire. The proposed current transformer provides a new method for electricity larceny prevention and on-line monitoring of the power grid in an electric system, thereby satisfying the development demands of the smart power grid.

  9. Systems biology: experimental design.

    Science.gov (United States)

    Kreutz, Clemens; Timmer, Jens

    2009-02-01

    Experimental design has a long tradition in statistics, engineering and life sciences, dating back to the beginning of the last century when optimal designs for industrial and agricultural trials were considered. In cell biology, the use of mathematical modeling approaches raises new demands on experimental planning. A maximum informative investigation of the dynamic behavior of cellular systems is achieved by an optimal combination of stimulations and observations over time. In this minireview, the existing approaches concerning this optimization for parameter estimation and model discrimination are summarized. Furthermore, the relevant classical aspects of experimental design, such as randomization, replication and confounding, are reviewed.

  10. Experimental design a chemometric approach

    CERN Document Server

    Deming, SN

    1987-01-01

    Now available in a paperback edition is a book which has been described as ``...an exceptionally lucid, easy-to-read presentation... would be an excellent addition to the collection of every analytical chemist. I recommend it with great enthusiasm.'' (Analytical Chemistry). Unlike most current textbooks, it approaches experimental design from the point of view of the experimenter, rather than that of the statistician. As the reviewer in `Analytical Chemistry' went on to say: ``Deming and Morgan should be given high praise for bringing the principles of experimental design to the level of the p

  11. Teaching experimental design.

    Science.gov (United States)

    Fry, Derek J

    2014-01-01

    Awareness of poor design and published concerns over study quality stimulated the development of courses on experimental design intended to improve matters. This article describes some of the thinking behind these courses and how the topics can be presented in a variety of formats. The premises are that education in experimental design should be undertaken with an awareness of educational principles, of how adults learn, and of the particular topics in the subject that need emphasis. For those using laboratory animals, it should include ethical considerations, particularly severity issues, and accommodate learners not confident with mathematics. Basic principles, explanation of fully randomized, randomized block, and factorial designs, and discussion of how to size an experiment form the minimum set of topics. A problem-solving approach can help develop the skills of deciding what are correct experimental units and suitable controls in different experimental scenarios, identifying when an experiment has not been properly randomized or blinded, and selecting the most efficient design for particular experimental situations. Content, pace, and presentation should suit the audience and time available, and variety both within a presentation and in ways of interacting with those being taught is likely to be effective. Details are given of a three-day course based on these ideas, which has been rated informative, educational, and enjoyable, and can form a postgraduate module. It has oral presentations reinforced by group exercises and discussions based on realistic problems, and computer exercises which include some analysis. Other case studies consider a half-day format and a module for animal technicians. © The Author 2014. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  12. Design of an Experimental Contemporary Physics Course which Develops the Full Experience of Scientific Research and Highlights Current Faculty Research

    Science.gov (United States)

    Yarrison-Rice, Jan M.; Jaeger, Herbert; Eid, Khalid F.

    2013-03-01

    From background literature searches and reading, to conducting experiments, to presenting results and writing a journal manuscript, Miami University has revised its second-year Experimental Contemporary Physics Course, Phy293, to follow a basic research model. We examined research that faculty were conducting and chose experiments which were strongly related to understanding the ongoing research in the Department, while being based in fundamental quantum mechanics and recent 21st century physics. Experiments often had common instrumentation and data analysis techniques which allowed for grouping them into 3 basic categories: 1) Spectroscopy of gases and solids, 2) Characterization of contemporary samples, and 3) Quantized systems in electronic, magnetic and nuclear physics. These experiments also supported our secondary goal of preparing students to enter our research laboratories. At Miami, we generally have between 25-35 second year students, so the laboratory course must be managed to maintain groups of 2-3 for the best student learning outcomes. We will report on course logistics, the grouping of experiments, and methods for assessing students' learning. Having run the revised, full experimental format of Phy293 a 3rd time, we feel confident stating that this course demonstrates to students ``how physics research in the 21st century is actually conducted!''

  13. NOAA NOS SOS, EXPERIMENTAL - Currents

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA NOS SOS server is part of the IOOS DIF SOS Project. The stations in this dataset have currents data. *These services are for testing and evaluation use...

  14. Top Quark Current Experimental Status

    CERN Document Server

    Juste, A

    2006-01-01

    Ten years after its discovery at the Tevatron collider, we still know little about the top quark. Its large mass suggests it may play a key role in the mechanism of Electroweak Symmetry Breaking (EWSB), or open a window of sensitivity to new physics related to EWSB and preferentially coupled to it. To determine whether this is the case, precision measurements of top quark properties are necessary. The high statistics samples being collected by the Tevatron experiments during Run II start to incisively probe the top quark sector. This report summarizes the experimental status of the top quark, focusing in particular on the recent measurements from the Tevatron.

  15. Minimax Current Density Coil Design

    CERN Document Server

    Poole, Michael; Lopez, Hector Sanchez; Ng, Michael; Crozier, Stuart; 10.1088/0022-3727/43/9/095001

    2010-01-01

    'Coil design' is an inverse problem in which arrangements of wire are designed to generate a prescribed magnetic field when energized with electric current. The design of gradient and shim coils for magnetic resonance imaging (MRI) are important examples of coil design. The magnetic fields that these coils generate are usually required to be both strong and accurate. Other electromagnetic properties of the coils, such as inductance, may be considered in the design process, which becomes an optimization problem. The maximum current density is additionally optimized in this work and the resultant coils are investigated for performance and practicality. Coils with minimax current density were found to exhibit maximally spread wires and may help disperse localized regions of Joule heating. They also produce the highest possible magnetic field strength per unit current for any given surface and wire size. Three different flavours of boundary element method that employ different basis functions (triangular elements...

  16. True Experimental Design.

    Science.gov (United States)

    Huck, Schuyler W.

    1991-01-01

    This poem, with stanzas in limerick form, refers humorously to the many threats to validity posed by problems in research design, including problems of sample selection, data collection, and data analysis. (SLD)

  17. Animal husbandry and experimental design.

    Science.gov (United States)

    Nevalainen, Timo

    2014-01-01

    If the scientist needs to contact the animal facility after any study to inquire about husbandry details, this represents a lost opportunity, which can ultimately interfere with the study results and their interpretation. There is a clear tendency for authors to describe methodological procedures down to the smallest detail, but at the same time to provide minimal information on animals and their husbandry. Controlling all major variables as far as possible is the key issue when establishing an experimental design. The other common mechanism affecting study results is a change in the variation. Factors causing bias or variation changes are also detectable within husbandry. Our lives and the lives of animals are governed by cycles: the seasons, the reproductive cycle, the weekend-working days, the cage change/room sanitation cycle, and the diurnal rhythm. Some of these may be attributable to routine husbandry, and the rest are cycles, which may be affected by husbandry procedures. Other issues to be considered are consequences of in-house transport, restrictions caused by caging, randomization of cage location, the physical environment inside the cage, the acoustic environment audible to animals, olfactory environment, materials in the cage, cage complexity, feeding regimens, kinship, and humans. Laboratory animal husbandry issues are an integral but underappreciated part of investigators' experimental design, which if ignored can cause major interference with the results. All researchers should familiarize themselves with the current routine animal care of the facility serving them, including their capabilities for the monitoring of biological and physicochemical environment.

  18. Experimental typography : reviewing the modernist and the current approaches

    OpenAIRE

    Makal, Eray

    1993-01-01

    Ankara : The Department of Graphic Design and Institute of Fine Arts, Bilkent Univ., 1993. Thesis (Master's) -- Bilkent University, 1993. Includes bibliographical references leaves 65-66. The intention of this study is to evaluate the experimental typography within the history of graphic design by taking in consideration of two epochs. The Modernist and The Current. Makal, Eray M.S.

  19. Yakima Hatchery Experimental Design : Annual Progress Report.

    Energy Technology Data Exchange (ETDEWEB)

    Busack, Craig; Knudsen, Curtis; Marshall, Anne

    1991-08-01

    This progress report details the results and status of Washington Department of Fisheries' (WDF) pre-facility monitoring, research, and evaluation efforts, through May 1991, designed to support the development of an Experimental Design Plan (EDP) for the Yakima/Klickitat Fisheries Project (YKFP), previously termed the Yakima/Klickitat Production Project (YKPP or Y/KPP). This pre- facility work has been guided by planning efforts of various research and quality control teams of the project that are annually captured as revisions to the experimental design and pre-facility work plans. The current objective are as follows: to develop genetic monitoring and evaluation approach for the Y/KPP; to evaluate stock identification monitoring tools, approaches, and opportunities available to meet specific objectives of the experimental plan; and to evaluate adult and juvenile enumeration and sampling/collection capabilities in the Y/KPP necessary to measure experimental response variables.

  20. Considering RNAi experimental design in parasitic helminths.

    Science.gov (United States)

    Dalzell, Johnathan J; Warnock, Neil D; McVeigh, Paul; Marks, Nikki J; Mousley, Angela; Atkinson, Louise; Maule, Aaron G

    2012-04-01

    Almost a decade has passed since the first report of RNA interference (RNAi) in a parasitic helminth. Whilst much progress has been made with RNAi informing gene function studies in disparate nematode and flatworm parasites, substantial and seemingly prohibitive difficulties have been encountered in some species, hindering progress. An appraisal of current practices, trends and ideals of RNAi experimental design in parasitic helminths is both timely and necessary for a number of reasons: firstly, the increasing availability of parasitic helminth genome/transcriptome resources means there is a growing need for gene function tools such as RNAi; secondly, fundamental differences and unique challenges exist for parasite species which do not apply to model organisms; thirdly, the inherent variation in experimental design, and reported difficulties with reproducibility undermine confidence. Ideally, RNAi studies of gene function should adopt standardised experimental design to aid reproducibility, interpretation and comparative analyses. Although the huge variations in parasite biology and experimental endpoints make RNAi experimental design standardization difficult or impractical, we must strive to validate RNAi experimentation in helminth parasites. To aid this process we identify multiple approaches to RNAi experimental validation and highlight those which we deem to be critical for gene function studies in helminth parasites.

  1. Optimal experimental design strategies for detecting hormesis.

    Science.gov (United States)

    Dette, Holger; Pepelyshev, Andrey; Wong, Weng Kee

    2011-12-01

    Hormesis is a widely observed phenomenon in many branches of life sciences, ranging from toxicology studies to agronomy, with obvious public health and risk assessment implications. We address optimal experimental design strategies for determining the presence of hormesis in a controlled environment using the recently proposed Hunt-Bowman model. We propose alternative models that have an implicit hormetic threshold, discuss their advantages over current models, and construct and study properties of optimal designs for (i) estimating model parameters, (ii) estimating the threshold dose, and (iii) testing for the presence of hormesis. We also determine maximin optimal designs that maximize the minimum of the design efficiencies when we have multiple design criteria or there is model uncertainty where we have a few plausible models of interest. We apply these optimal design strategies to a teratology study and show that the proposed designs outperform the implemented design by a wide margin for many situations.

  2. Elements of Bayesian experimental design

    Energy Technology Data Exchange (ETDEWEB)

    Sivia, D.S. [Rutherford Appleton Lab., Oxon (United Kingdom)

    1997-09-01

    We consider some elements of the Bayesian approach that are important for optimal experimental design. While the underlying principles used are very general, and are explained in detail in a recent tutorial text, they are applied here to the specific case of characterising the inferential value of different resolution peakshapes. This particular issue was considered earlier by Silver, Sivia and Pynn (1989, 1990a, 1990b), and the following presentation confirms and extends the conclusions of their analysis.

  3. Graphical Models for Quasi-Experimental Designs

    Science.gov (United States)

    Kim, Yongnam; Steiner, Peter M.; Hall, Courtney E.; Su, Dan

    2016-01-01

    Experimental and quasi-experimental designs play a central role in estimating cause-effect relationships in education, psychology, and many other fields of the social and behavioral sciences. This paper presents and discusses the causal graphs of experimental and quasi-experimental designs. For quasi-experimental designs the authors demonstrate…

  4. Experimental design research approaches, perspectives, applications

    CERN Document Server

    Stanković, Tino; Štorga, Mario

    2016-01-01

    This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current research practice where methods are diverging and integration between individual, team and organizational under...

  5. Experimental Setup for the Investigation of Superconducting Persistent Current

    Science.gov (United States)

    2015-09-01

    NOTES 14. ABSTRACT We report on a recent experimental setup for the investigation of the relaxation rate of the persistent current in an assembly of...at cryo-temperatures in magnetic field at time scale of seconds to hours. 15. SUBJECT TERMS persistent current, 2G HTS, coated conductor, relaxation ... activation . One unknown aspect is the variation of the coils’ position with temperature from room to cryogenic. A better design of the coils assembly

  6. Teaching experimental design to biologists.

    Science.gov (United States)

    Zolman, J F

    1999-12-01

    The teaching of research design and data analysis to our graduate students has been a persistent problem. A course is described in which students, early in their graduate training, obtain extensive practice in designing experiments and interpreting data. Lecture-discussions on the essentials of biostatistics are given, and then these essentials are repeatedly reviewed by illustrating their applications and misapplications in numerous research design problems. Students critique these designs and prepare similar problems for peer evaluation. In most problems the treatments are confounded by extraneous variables, proper controls may be absent, or data analysis may be incorrect. For each problem, students must decide whether the researchers' conclusions are valid and, if not, must identify a fatal experimental flaw. Students learn that an experiment is a well-conceived plan for data collection, analysis, and interpretation. They enjoy the interactive evaluations of research designs and appreciate the repetitive review of common flaws in different experiments. They also benefit from their practice in scientific writing and in critically evaluating their peers' designs.

  7. Optimal experimental design strategies for detecting hormesis

    OpenAIRE

    2010-01-01

    Hormesis is a widely observed phenomenon in many branches of life sciences ranging from toxicology studies to agronomy with obvious public health and risk assessment implications. We address optimal experimental design strategies for determining the presence of hormesis in a controlled environment using the recently proposed Hunt-Bowman model. We propose alternative models that have an implicit hormetic threshold, discuss their advantages over current models, construct and study properties of...

  8. Web Based Learning Support for Experimental Design in Molecular Biology.

    Science.gov (United States)

    Wilmsen, Tinri; Bisseling, Ton; Hartog, Rob

    An important learning goal of a molecular biology curriculum is a certain proficiency level in experimental design. Currently students are confronted with experimental approaches in textbooks, in lectures and in the laboratory. However, most students do not reach a satisfactory level of competence in the design of experimental approaches. This…

  9. Quasi-Experimental Designs for Causal Inference

    Science.gov (United States)

    Kim, Yongnam; Steiner, Peter

    2016-01-01

    When randomized experiments are infeasible, quasi-experimental designs can be exploited to evaluate causal treatment effects. The strongest quasi-experimental designs for causal inference are regression discontinuity designs, instrumental variable designs, matching and propensity score designs, and comparative interrupted time series designs. This…

  10. Halo current diagnostic system of experimental advanced superconducting tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Chen, D. L.; Shen, B.; Sun, Y.; Qian, J. P., E-mail: jpqian@ipp.ac.cn; Wang, Y.; Xiao, B. J. [Institute of Plasma Physics, Chinese Academy of Sciences, P.O. Box 1126, Hefei 230031 (China); Granetz, R. S. [MIT Plasma Science and Fusion Center, Cambridge, Massachusetts 02139 (United States)

    2015-10-15

    The design, calibration, and installation of disruption halo current sensors for the Experimental Advanced Superconducting Tokamak are described in this article. All the sensors are Rogowski coils that surround conducting structures, and all the signals are analog integrated. Coils with two different cross-section sizes have been fabricated, and their mutual inductances are calibrated. Sensors have been installed to measure halo currents in several different parts of both the upper divertor (tungsten) and lower divertor (graphite) at several toroidal locations. Initial measurements from disruptions show that the halo current diagnostics are working well.

  11. Halo current diagnostic system of experimental advanced superconducting tokamak

    Science.gov (United States)

    Chen, D. L.; Shen, B.; Granetz, R. S.; Sun, Y.; Qian, J. P.; Wang, Y.; Xiao, B. J.

    2015-10-01

    The design, calibration, and installation of disruption halo current sensors for the Experimental Advanced Superconducting Tokamak are described in this article. All the sensors are Rogowski coils that surround conducting structures, and all the signals are analog integrated. Coils with two different cross-section sizes have been fabricated, and their mutual inductances are calibrated. Sensors have been installed to measure halo currents in several different parts of both the upper divertor (tungsten) and lower divertor (graphite) at several toroidal locations. Initial measurements from disruptions show that the halo current diagnostics are working well.

  12. Experimental design methods for bioengineering applications.

    Science.gov (United States)

    Keskin Gündoğdu, Tuğba; Deniz, İrem; Çalışkan, Gülizar; Şahin, Erdem Sefa; Azbar, Nuri

    2016-01-01

    Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific interest, and each study area is affected and governed by many different factors. Briefly analyzing the important factors and selecting an experimental design for optimization are very effective tools for the design of any bioprocess under question. This review summarizes experimental design methods that can be used to investigate various factors relating to bioengineering processes. The experimental methods generally used in bioengineering are as follows: full factorial design, fractional factorial design, Plackett-Burman design, Taguchi design, Box-Behnken design and central composite design. These design methods are briefly introduced, and then the application of these design methods to study different bioengineering processes is analyzed.

  13. Teaching Experimental Design to Elementary School Pupils in Greece

    Science.gov (United States)

    Karampelas, Konstantinos

    2016-01-01

    This research is a study about the possibility to promote experimental design skills to elementary school pupils. Experimental design and the experiment process are foundational elements in current approaches to Science Teaching, as they provide learners with profound understanding about knowledge construction and science inquiry. The research was…

  14. Experimental Design and Some Threats to Experimental Validity: A Primer

    Science.gov (United States)

    Skidmore, Susan

    2008-01-01

    Experimental designs are distinguished as the best method to respond to questions involving causality. The purpose of the present paper is to explicate the logic of experimental design and why it is so vital to questions that demand causal conclusions. In addition, types of internal and external validity threats are discussed. To emphasize the…

  15. Design of hydrodynamic performance experimental system of horizontal axis tidal current energy blade%水平轴潮流能桨叶水动力性能实验系统设计

    Institute of Scientific and Technical Information of China (English)

    林躜; 张利; 张惠娣; 陈俊华

    2016-01-01

    Based on the analysis of the characteristics of the impeller’s design for horizontal axis tidal current energy turbine .a 1 kW hydrodynamic performance test system of horizontal axis tidal current energy blade is achieved .The experimental system consists of the making flow subsystem ,tidal current energy capturing subsystem ,transmission subsystem ,measuring and control subsystem and load resistor .It can simulate maximum 2m/s flow velocity .Many hydrodynamic performance tests are supported in the experimental system such as variable tip speed ratio ,mounting angle and wing profile of turbine blade .Using airMAX wireless technology ,the experimental system is capable of wireless remote control and data acquisition , and accomplishes procedure management to monitor the entire experimental system .Under 1 .5 m/s flow velocity energy capture efficiency of blade was tested ,and it is proved that the experimental system is stable ,reliable and easy to control .The experimental system has laid the foundation for blade performance test and wing profile design .%在分析现有水平轴潮流能发电水轮机设计特点的基础上,设计了1 kw水平轴潮流能捕获桨叶水动力性能实验系统。该实验系统由造流子系统、潮流能捕获子系统、传动子系统、测控子系统和负载组成。该系统可模拟2m/s以下潮流,能实现不同尖速比、桨叶安装角、桨叶翼型等多种水动力性能测试研究。该系统应用了无线airM AX技术,能够无线远程控制和数据采集,实现了整个系统的流程化管理和监控。在1.5 m/s模拟潮流下,利用该系统对桨叶的捕能效率进行测试,测试表明系统运行稳定、工作可靠、控制方便。该实验系统奠定了桨叶翼型设计、验证桨叶性能等方面的基础。

  16. The Experimental Design Ability Test (EDAT)

    Science.gov (United States)

    Sirum, Karen; Humburg, Jennifer

    2011-01-01

    Higher education goals include helping students develop evidence based reasoning skills; therefore, scientific thinking skills such as those required to understand the design of a basic experiment are important. The Experimental Design Ability Test (EDAT) measures students' understanding of the criteria for good experimental design through their…

  17. Design, theoretical analysis, and experimental verification of a CMOS current integrator with 1.2 × 2.05 µm2 microelectrode array for high-sensitivity bacterial counting

    Science.gov (United States)

    Gamo, Kohei; Nakazato, Kazuo; Niitsu, Kiichi

    2017-01-01

    In this paper, we present the design and experimental verification of an amperometric CMOS-based sensor with a current integrator and a 1.2 × 2.05 µm2 bacterial-sized microelectrode array for high-sensitivity bacterial counting. For high-sensitivity bacterial counting with a sufficient signal-to-noise ratio (SNR), noise must be reduced because bacterial-sized microelectrodes can handle only a low current of the order of 100 pA. Thus, we implement a current integrator that is highly effective for noise reduction. Furthermore, for the first time, we use the current integrator in conjunction with the bacterial-sized microelectrode array. On the basis of the results of the proposed current integration, we successfully reduce noise and achieve a high SNR of 30.4 dB. To verify the effectiveness of the proposed CMOS-based sensor, we perform two-dimensional counting of microbeads, which are almost of the same size as bacteria. The measurement results demonstrate successful high-sensitivity two-dimensional (2D) counting of microbeads with a high SNR of 27 dB.

  18. Quasi experimental designs in pharmacist intervention research.

    Science.gov (United States)

    Krass, Ines

    2016-06-01

    Background In the field of pharmacist intervention research it is often difficult to conform to the rigorous requirements of the "true experimental" models, especially the requirement of randomization. When randomization is not feasible, a practice based researcher can choose from a range of "quasi-experimental designs" i.e., non-randomised and at time non controlled. Objective The aim of this article was to provide an overview of quasi-experimental designs, discuss their strengths and weaknesses and to investigate their application in pharmacist intervention research over the previous decade. Results In the literature quasi experimental studies may be classified into five broad categories: quasi-experimental design without control groups; quasi-experimental design that use control groups with no pre-test; quasi-experimental design that use control groups and pre-tests; interrupted time series and stepped wedge designs. Quasi-experimental study design has consistently featured in the evolution of pharmacist intervention research. The most commonly applied of all quasi experimental designs in the practice based research literature are the one group pre-post-test design and the non-equivalent control group design i.e., (untreated control group with dependent pre-tests and post-tests) and have been used to test the impact of pharmacist interventions in general medications management as well as in specific disease states. Conclusion Quasi experimental studies have a role to play as proof of concept, in the pilot phases of interventions when testing different intervention components, especially in complex interventions. They serve to develop an understanding of possible intervention effects: while in isolation they yield weak evidence of clinical efficacy, taken collectively, they help build a body of evidence in support of the value of pharmacist interventions across different practice settings and countries. However, when a traditional RCT is not feasible for

  19. Program Calculates Current Densities Of Electronic Designs

    Science.gov (United States)

    Cox, Brian

    1996-01-01

    PDENSITY computer program calculates current densities for use in calculating power densities of electronic designs. Reads parts-list file for given design, file containing current required for each part, and file containing size of each part. For each part in design, program calculates current density in units of milliamperes per square inch. Written by use of AWK utility for Sun4-series computers running SunOS 4.x and IBM PC-series and compatible computers running MS-DOS. Sun version of program (NPO-19588). PC version of program (NPO-19171).

  20. Design of Formulated Products: Experimental Component

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul; Cheng, Y. S.

    2012-01-01

    : computer-aided design (Stage 1), which generates a list of feasible candidates, experimental planning (Stage 2), which generates a list of experiments and checks the available experimental set-ups, and experimental testing (Stage 3), which measures the necessary data and verifies the desirable attributes...

  1. Experimental design and priority PLS regression

    DEFF Research Database (Denmark)

    Høskuldsson, Agnar

    1996-01-01

    Rules, ideas and algorithms of the H-principle are used to analyse models that are derived from experimental design. Some of the basic ideas of experimental design are reviewed and related to the methodology of the H-principle. New methods of optimal response surfaces are developed....

  2. Light Experimental Supercruiser Conceptual Design

    Science.gov (United States)

    1976-07-01

    RADIUS-200 TOGW Fifun 118. Arrow Point Design Ptnittmn* Carpet 193 4.3 VEHICLE PARAMETRIC TRADES (Continued) Sustained Load Factor--The third...0.06 ^s’ ^60^^ ^ ^**«» ^ >^^»M00 «^ /^ / —~ <. xf ’"»^C^ ^ -< >^ X*** Fifun 120. Arrow Su$t»lmd Lo§d factor Vtrwt

  3. Some Thoughts on Experimental Design.

    Science.gov (United States)

    Stern, Claudio D

    2017-01-01

    Perhaps even more important than the techniques themselves are the quality of the biological questions asked and the design of the experiments devised to answer them. This chapter summarizes some of the key issues and also touches on how the same principles affect scholarly use of the scientific literature and good peer-reviewing practices.

  4. Experimental Design: Review and Comment.

    Science.gov (United States)

    1984-02-01

    and early work in the subject was done by Wald (1943), Hotelling (1944), and Elfving (1952). The major contributions to the area, however, were made by...Kiefer (1958, 1959) and Kiefer and Wolfowitz (1959, 1960), who synthesized and greatly extended the previous work. Although the ideas of optimal...design theory is the general equivalence theorem (Kiefer and Wolfowitz 1960), which links D- and G-optimality. The theorem is phrased in terms of

  5. Chemicals-Based Formulation Design: Virtual Experimentations

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    2011-01-01

    This paper presents a systematic procedure for virtual experimentations related to the design of liquid formulated products. All the experiments that need to be performed when designing a liquid formulated product (lotion), such as ingredients selection and testing, solubility tests, property mea...... on the design of an insect repellent lotion will show that the software is an essential instrument in decision making, and that it reduces time and resources since experimental efforts can be focused on one or few product alternatives....

  6. Design of Uranium Solution Critical Experimental Device

    Institute of Scientific and Technical Information of China (English)

    YI; Da-yong; GUO; Zhi-jia; YAO; Cheng-zhi; SHI; Chen-lei

    2012-01-01

    <正>In 2012, Department of reactor engineering design completes the design and mechanical analysis of Uranium solution critical experimental device. According to user’s requirements and nuclear safety regulations, design and analysis mainly involves two sets of core structure, uranium solution loop, water loop and experimental bench, etc. The core which includes a core vessel, reactor core support, safety rods, control rods, and so on, is used for containing uranium solution and fuel element and fulfilling the

  7. An Introduction to Experimental Design Research

    DEFF Research Database (Denmark)

    2016-01-01

    Design research brings together influences from the whole gamut of social, psychological, and more technical sciences to create a tradition of empirical study stretching back over 50 years (Horvath 2004; Cross 2007). A growing part of this empirical tradition is experimental, which has gained...... in importance as the field has matured. As in other evolving disciplines, e.g. behavioural psychology, this maturation brings with it ever-greater scientific and methodological demands (Reiser 1939; Dorst 2008). In particular, the experimental paradigm holds distinct and significant challenges for the modern...... design researcher. Thus, this book brings together leading researchers from across design research in order to provide the reader with a foundation in experimental design research; an appreciation of possible experimental perspectives; and insight into how experiments can be used to build robust...

  8. Censored Weibull Distributed Data in Experimental Design

    OpenAIRE

    Støtvig, Jeanett Gunneklev

    2014-01-01

    Give an introduction to experimental design. Investigate how four methods handle Weibull distributed censored data, where the four methods are the quick and dirty method, the maximum likelihood method, single imputation and multiple imputation.

  9. Experimental design of a waste glass study

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, G.F.; Redgate, P.E.; Hrma, P.

    1995-04-01

    A Composition Variation Study (CVS) is being performed to support a future high-level waste glass plant at Hanford. A total of 147 glasses, covering a broad region of compositions melting at approximately 1150{degrees}C, were tested in five statistically designed experimental phases. This paper focuses on the goals, strategies, and techniques used in designing the five phases. The overall strategy was to investigate glass compositions on the boundary and interior of an experimental region defined by single- component, multiple-component, and property constraints. Statistical optimal experimental design techniques were used to cover various subregions of the experimental region in each phase. Empirical mixture models for glass properties (as functions of glass composition) from previous phases wee used in designing subsequent CVS phases.

  10. Chemical-Based Formulation Design: Virtual Experimentation

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    This paper presents a software, the virtual Product-Process Design laboratory (virtual PPD-lab) and the virtual experimental scenarios for design/verification of consumer oriented liquid formulated products where the software can be used. For example, the software can be employed for the design...... system engineering community, it is possible now to replace, at least, some of the experimental steps with efficient and validated model-based approaches. For example, the search space can be significantly reduced through computer-aided screenings of the active ingredient (AI), the solvent mixture......, the additives and/or their mixtures (formulations). Therefore, the experimental resources can focus on a few candidate product formulations to find the best product. The virtual PPD-lab allows various options for experimentations related to design and/or verification of the product. For example, the selection...

  11. New product development using experimental design

    OpenAIRE

    Zhang, Zhihai

    1998-01-01

    New product development is one of the most powerful but difficult activities in business. It is also a very important factor affecting final product quality. There are many techniques available for new product development. Experimental design is now regarded as one of the most significant techniques. In this article, we will discuss how to use the technique of experimental design in developing a new product - an extrusion press. In order to provide a better understanding of this specific proc...

  12. Design principles for shift current photovoltaics.

    Science.gov (United States)

    Cook, Ashley M; M Fregoso, Benjamin; de Juan, Fernando; Coh, Sinisa; Moore, Joel E

    2017-01-25

    While the basic principles of conventional solar cells are well understood, little attention has gone towards maximizing the efficiency of photovoltaic devices based on shift currents. By analysing effective models, here we outline simple design principles for the optimization of shift currents for frequencies near the band gap. Our method allows us to express the band edge shift current in terms of a few model parameters and to show it depends explicitly on wavefunctions in addition to standard band structure. We use our approach to identify two classes of shift current photovoltaics, ferroelectric polymer films and single-layer orthorhombic monochalcogenides such as GeS, which display the largest band edge responsivities reported so far. Moreover, exploring the parameter space of the tight-binding models that describe them we find photoresponsivities that can exceed 100 mA W(-1). Our results illustrate the great potential of shift current photovoltaics to compete with conventional solar cells.

  13. Design principles for shift current photovoltaics

    Science.gov (United States)

    Cook, Ashley M.; M. Fregoso, Benjamin; de Juan, Fernando; Coh, Sinisa; Moore, Joel E.

    2017-01-01

    While the basic principles of conventional solar cells are well understood, little attention has gone towards maximizing the efficiency of photovoltaic devices based on shift currents. By analysing effective models, here we outline simple design principles for the optimization of shift currents for frequencies near the band gap. Our method allows us to express the band edge shift current in terms of a few model parameters and to show it depends explicitly on wavefunctions in addition to standard band structure. We use our approach to identify two classes of shift current photovoltaics, ferroelectric polymer films and single-layer orthorhombic monochalcogenides such as GeS, which display the largest band edge responsivities reported so far. Moreover, exploring the parameter space of the tight-binding models that describe them we find photoresponsivities that can exceed 100 mA W-1. Our results illustrate the great potential of shift current photovoltaics to compete with conventional solar cells.

  14. Optimal Bayesian Experimental Design for Combustion Kinetics

    KAUST Repository

    Huan, Xun

    2011-01-04

    Experimental diagnostics play an essential role in the development and refinement of chemical kinetic models, whether for the combustion of common complex hydrocarbons or of emerging alternative fuels. Questions of experimental design—e.g., which variables or species to interrogate, at what resolution and under what conditions—are extremely important in this context, particularly when experimental resources are limited. This paper attempts to answer such questions in a rigorous and systematic way. We propose a Bayesian framework for optimal experimental design with nonlinear simulation-based models. While the framework is broadly applicable, we use it to infer rate parameters in a combustion system with detailed kinetics. The framework introduces a utility function that reflects the expected information gain from a particular experiment. Straightforward evaluation (and maximization) of this utility function requires Monte Carlo sampling, which is infeasible with computationally intensive models. Instead, we construct a polynomial surrogate for the dependence of experimental observables on model parameters and design conditions, with the help of dimension-adaptive sparse quadrature. Results demonstrate the efficiency and accuracy of the surrogate, as well as the considerable effectiveness of the experimental design framework in choosing informative experimental conditions.

  15. Using experimental design to define boundary manikins.

    Science.gov (United States)

    Bertilsson, Erik; Högberg, Dan; Hanson, Lars

    2012-01-01

    When evaluating human-machine interaction it is central to consider anthropometric diversity to ensure intended accommodation levels. A well-known method is the use of boundary cases where manikins with extreme but likely measurement combinations are derived by mathematical treatment of anthropometric data. The supposition by that method is that the use of these manikins will facilitate accommodation of the expected part of the total, less extreme, population. In literature sources there are differences in how many and in what way these manikins should be defined. A similar field to the boundary case method is the use of experimental design in where relationships between affecting factors of a process is studied by a systematic approach. This paper examines the possibilities to adopt methodology used in experimental design to define a group of manikins. Different experimental designs were adopted to be used together with a confidence region and its axes. The result from the study shows that it is possible to adapt the methodology of experimental design when creating groups of manikins. The size of these groups of manikins depends heavily on the number of key measurements but also on the type of chosen experimental design.

  16. Experimental design in chromatography: a tutorial review.

    Science.gov (United States)

    Hibbert, D Brynn

    2012-12-01

    The ability of a chromatographic method to successful separate, identify and quantitate species is determined by many factors, many of which are in the control of the experimenter. When attempting to discover the important factors and then optimise a response by tuning these factors, experimental design (design of experiments, DoE) gives a powerful suite of statistical methodology. Advantages include modelling by empirical functions, not requiring detailed knowledge of the underlying physico-chemical properties of the system, a defined number of experiments to be performed, and available software to accomplish the task. Two uses of DoE in chromatography are for showing lack of significant effects in robustness studies for method validation, and for identifying significant factors and then optimising a response with respect to them in method development. Plackett-Burman designs are widely used in validation studies, and fractional factorial designs and their extensions such as central composite designs are the most popular optimisers. Box-Behnken and Doehlert designs are becoming more used as efficient alternatives. If it is not possible to practically realise values of the factors required by experimental designs, or if there is a constraint on the total number of experiments that can be done, then D-optimal designs can be very powerful. Examples of the use of DoE in chromatography are reviewed. Recommendations are given on how to report DoE studies in the literature.

  17. EBTS:DESIGN AND EXPERIMENTAL STUDY.

    Energy Technology Data Exchange (ETDEWEB)

    PIKIN,A.; ALESSI,J.; BEEBE,E.; KPONOU,A.; PRELEC,K.; KUZNETSOV,G.; TIUNOV,M.

    2000-11-06

    Experimental study of the BNL Electron Beam Test Stand (EBTS), which is a prototype of the Relativistic Heavy Ion Collider (RHIC) Electron Beam Ion Source (EBIS), is currently underway. The basic physics and engineering aspects of a high current EBIS implemented in EBTS are outlined and construction of its main systems is presented. Efficient transmission of a 10 A electron beam through the ion trap has been achieved. Experimental results on generation of multiply charged ions with both continuous gas and external ion injection confirm stable operation of the ion trap.

  18. Current trends in high temperature design

    Energy Technology Data Exchange (ETDEWEB)

    Marriott, D.L. (Illinois Univ., Urbana, IL (United States). Dept. of Mechanical Engineering)

    1992-01-01

    A review of high temperature design guidelines has been carried out in preparation for designing a solar storage module for the Freedom Spacelab. Three major guidelines, N47, R5 and RCC-MR form the basis of the survey. The main issues with current, mature design in the power industry appear to be adequately covered by these guidelines. A significant finding is that long established models of material damage have survived the test of time very well. A new design regime referred to as Very High Temperature Design (VHTD) is identified. The characteristics of this regime are changing material properties which require some changes in philosophy in drafting of future codes, particularly in regard to definitions of yield strengths and other design allowables. Finally, there is some discussion of the more general use of the stress/strain plane, e.g. isochronous curves, for representation of very complex material constitutive behaviour. A concept called the 'Relaxation Locus', which summarizes essential local constrained component behavior, is introduced and its application to high temperature design problems is discussed briefly. (author).

  19. The nonstandard algorithm for constructing efficient conjoint experimental designs

    Directory of Open Access Journals (Sweden)

    Kuzmanović Marija

    2008-01-01

    Full Text Available Conjoint analysis is a research technique for measuring consumer preferences, and it is a method for simulating consumers' possible reactions to changes in current products or newly introduced products into an existing competitive market. One of the most critical steps in Conjoint analysis application is experimental designs construction. The purpose of an experimental design is to give a rough overall idea as to the shape of the experimental response surface, while only requiring a relatively small number of runs. These designs are expected to be orthogonal and balanced in an ideal case. In practice, though, it is hard to construct optimal designs and thus constructing of near optimal and efficient designs is carried out. There are several ways to quantify the relative efficiency of experimental designs. The choice of measure will determine which types of experimental designs are favored as well as the algorithms for choosing efficient designs. In this paper it is proposed the algorithm which combines one standard and one non-standard optimality criteria. The computational experiments were made, and results of comparison with algorithm implemented in commercial package SPSS confirm the efficiency of the proposed algorithm. .

  20. Superconducting Fault Current Limiter optimized design

    Energy Technology Data Exchange (ETDEWEB)

    Tixador, Pascal, E-mail: Pascal.Tixador@grenoble-inp.fr [Univ. Grenoble Alpes, G2Elab – Institut Néel, F-38000 Grenoble (France); CNRS, G2Elab – Institut Néel, F-38000 Grenoble (France); Badel, Arnaud [CNRS, G2Elab – Institut Néel, F-38000 Grenoble (France)

    2015-11-15

    Highlights: • A low cost design of YBCO Fault Current Limiter. • A high resistance conductor for reduced length. • An asymmetrical YBCO conductor (injection and AC losses). • A thickness suitable for non destructive hot spots. - Abstract: The SuperConducting Fault Current Limiter (SCFCL) appears as one of the most promising SC applications for the electrical grids. Despite its advantages and many successful field experiences the market of SCFCL has difficulties to take off even if the first orders for permanent operation in grids are taken. The analytical design of resistive SCFCL will be discussed with the objective to reduce the quantity of SC conductor (length and section) to be more cost-effective. For that the SC conductor must have a high resistivity in normal state. It can be achieved by using high resistivity alloy for shunt, such as Hastelloy®. One of the most severe constraint is that the SCFCL should operate safely for any faults, especially those with low prospective short-circuit currents. This constraint requires to properly design the thickness of the SC tape in order to limit the hot spot temperature. An operation at 65 K appears as very interesting since it decreases the SC cost at least by a factor 2 with a simple LN2 cryogenics. Taking into account the cost reduction in a near future, the SC conductor cost could be rather low, half a dollar per kV A.

  1. Current fusion power plant design concepts

    Energy Technology Data Exchange (ETDEWEB)

    Gore, B.F.; Murphy, E.S.

    1976-09-01

    Nine current U.S. designs for fusion power plants are described in this document. Summary tabulations include a tenth concept, for which the design document was unavailable during preparation of the descriptions. The information contained in the descriptions was used to define an envelope of fusion power plant characteristics which formed the basis for definition of reference first commercial fusion power plant design. A brief prose summary of primary plant features introduces each of the descriptions contained in the body of this document. In addition, summary tables are presented. These tables summarize in side-by-side fashion, plant parameters, processes, combinations of materials used, requirements for construction materials, requirements for replacement materials during operation, and production of wastes.

  2. Experimental Study and Design of Balloon expandable Endovascular Stent Expansion

    Institute of Scientific and Technical Information of China (English)

    WANG Yue-xuan; YI Hong; NI Zhong-hua

    2005-01-01

    The application background and experimental research overview of medical endovascular stent are presented. Based on the analytical comparison of the current research achievements, the life cycle of medical endovascular stent is pointed out and the characteristics of stent expansion in the life cycle are emphasized on.The experimental scheme of in vitro stent expansion based on the machine vision technology in LabVIEW is presented. The selection and usage of the chosen component devices and design of measurement program for experiment are expatiated. A special drug-loading stent was expanded on the assembled platform of selected equipments and experimental results were analyzed. The experimental scheme presented in the paper provides powerful experimental support for the optimization of stent design and computer simulation of stent expansion by the finite element analysis.

  3. Experimental observation of direct current voltage-induced phase synchronization

    Indian Academy of Sciences (India)

    Haihong Li; Weiqing Liu; Qiongling Dai; Jinghua Xiao

    2006-09-01

    The dynamics of two uncoupled distinct Chua circuits driven by a common direct current voltage is explored experimentally. It was found that, with increasing current intensity, the dominant frequencies of these two Chua circuits will first vary at different speeds, approach an identical value for a certain current intensity and then separate. Techniques such as synchronization index and phase difference distribution were employed to analyze the phase coherence between these two Chua circuits.

  4. Estimating Intervention Effects across Different Types of Single-Subject Experimental Designs: Empirical Illustration

    Science.gov (United States)

    Moeyaert, Mariola; Ugille, Maaike; Ferron, John M.; Onghena, Patrick; Heyvaert, Mieke; Beretvas, S. Natasha; Van den Noortgate, Wim

    2015-01-01

    The purpose of this study is to illustrate the multilevel meta-analysis of results from single-subject experimental designs of different types, including AB phase designs, multiple-baseline designs, ABAB reversal designs, and alternating treatment designs. Current methodological work on the meta-analysis of single-subject experimental designs…

  5. Optimal Experimental Design for Model Discrimination

    Science.gov (United States)

    Myung, Jay I.; Pitt, Mark A.

    2009-01-01

    Models of a psychological process can be difficult to discriminate experimentally because it is not easy to determine the values of the critical design variables (e.g., presentation schedule, stimulus structure) that will be most informative in differentiating them. Recent developments in sampling-based search methods in statistics make it…

  6. Design of 162 MHz RF Experimental Cavity

    Institute of Scientific and Technical Information of China (English)

    YIN; Zhi-guo; CAO; Xue-long; GUO; Juan-juan; JI; Bin; FU; Xiao-liang; WEI; Jun-yi

    2015-01-01

    In this paper,a 162MHz RF experimental cavity is designed to study the multipacting multiplier effect of the medium and the metal electrode and its relationship with the plate surface characteristics,and to find out the method for inhibiting multipacting multiplier effects.The

  7. New product development using experimental design

    NARCIS (Netherlands)

    Zhang, Zhihai

    1998-01-01

    New product development is one of the most powerful but difficult activities in business. It is also a very important factor affecting final product quality. There are many techniques available for new product development. Experimental design is now regarded as one of the most significant techniques

  8. Designed patterns: flexible control of precipitation through electric currents.

    Science.gov (United States)

    Bena, I; Droz, M; Lagzi, I; Martens, K; Rácz, Z; Volford, A

    2008-08-15

    Understanding and controlling precipitation patterns formed in reaction-diffusion processes is of fundamental importance with high potential for technical applications. Here we present a theory showing that precipitation resulting from reactions among charged agents can be controlled by an appropriately designed, time-dependent electric current. Examples of current dynamics yielding periodic bands of prescribed wavelength, as well as more complicated structures are given. The pattern control is demonstrated experimentally using the reaction-diffusion process 2AgNO3 + K2Cr2O7-->under Ag2Cr2O7 + 2KNO3.

  9. Superconducting Fault Current Limiter optimized design

    Science.gov (United States)

    Tixador, Pascal; Badel, Arnaud

    2015-11-01

    The SuperConducting Fault Current Limiter (SCFCL) appears as one of the most promising SC applications for the electrical grids. Despite its advantages and many successful field experiences the market of SCFCL has difficulties to take off even if the first orders for permanent operation in grids are taken. The analytical design of resistive SCFCL will be discussed with the objective to reduce the quantity of SC conductor (length and section) to be more cost-effective. For that the SC conductor must have a high resistivity in normal state. It can be achieved by using high resistivity alloy for shunt, such as Hastelloy®. One of the most severe constraint is that the SCFCL should operate safely for any faults, especially those with low prospective short-circuit currents. This constraint requires to properly design the thickness of the SC tape in order to limit the hot spot temperature. An operation at 65 K appears as very interesting since it decreases the SC cost at least by a factor 2 with a simple LN2 cryogenics. Taking into account the cost reduction in a near future, the SC conductor cost could be rather low, half a dollar per kV A.

  10. Involving students in experimental design: three approaches.

    Science.gov (United States)

    McNeal, A P; Silverthorn, D U; Stratton, D B

    1998-12-01

    Many faculty want to involve students more actively in laboratories and in experimental design. However, just "turning them loose in the lab" is time-consuming and can be frustrating for both students and faculty. We describe three different ways of providing structures for labs that require students to design their own experiments but guide the choices. One approach emphasizes invertebrate preparations and classic techniques that students can learn fairly easily. Students must read relevant primary literature and learn each technique in one week, and then design and carry out their own experiments in the next week. Another approach provides a "design framework" for the experiments so that all students are using the same technique and the same statistical comparisons, whereas their experimental questions differ widely. The third approach involves assigning the questions or problems but challenging students to design good protocols to answer these questions. In each case, there is a mixture of structure and freedom that works for the level of the students, the resources available, and our particular aims.

  11. Design and Experimental Implementation of Bipedal robot

    Directory of Open Access Journals (Sweden)

    Sreejith C

    2012-09-01

    Full Text Available Biped robots have better mobility than conventional wheeled robots, but they tend to tip over easily. To be able to walk stably in various environments, such as on rough terrain, up and down slopes, or in regions containing obstacles, it is necessary for the robot to adapt to the ground conditions with a foot motion, and maintain its stability with a torso motion. In this paper, we first formulate the design and walking pattern for a bipedal robot and then a kicking robot has been developed for experimental verification. Finally, the correlation between the design and the walking patterns is described through simulation studies, and the effectiveness of the proposed methods is confirmed by simulation examples and experimental results.

  12. Bioinspiration: applying mechanical design to experimental biology.

    Science.gov (United States)

    Flammang, Brooke E; Porter, Marianne E

    2011-07-01

    The production of bioinspired and biomimetic constructs has fostered much collaboration between biologists and engineers, although the extent of biological accuracy employed in the designs produced has not always been a priority. Even the exact definitions of "bioinspired" and "biomimetic" differ among biologists, engineers, and industrial designers, leading to confusion regarding the level of integration and replication of biological principles and physiology. By any name, biologically-inspired mechanical constructs have become an increasingly important research tool in experimental biology, offering the opportunity to focus research by creating model organisms that can be easily manipulated to fill a desired parameter space of structural and functional repertoires. Innovative researchers with both biological and engineering backgrounds have found ways to use bioinspired models to explore the biomechanics of organisms from all kingdoms to answer a variety of different questions. Bringing together these biologists and engineers will hopefully result in an open discourse of techniques and fruitful collaborations for experimental and industrial endeavors.

  13. Fundamentals of statistical experimental design and analysis

    CERN Document Server

    Easterling, Robert G

    2015-01-01

    Professionals in all areas - business; government; the physical, life, and social sciences; engineering; medicine, etc. - benefit from using statistical experimental design to better understand their worlds and then use that understanding to improve the products, processes, and programs they are responsible for. This book aims to provide the practitioners of tomorrow with a memorable, easy to read, engaging guide to statistics and experimental design. This book uses examples, drawn from a variety of established texts, and embeds them in a business or scientific context, seasoned with a dash of humor, to emphasize the issues and ideas that led to the experiment and the what-do-we-do-next? steps after the experiment. Graphical data displays are emphasized as means of discovery and communication and formulas are minimized, with a focus on interpreting the results that software produce. The role of subject-matter knowledge, and passion, is also illustrated. The examples do not require specialized knowledge, and t...

  14. Sequential experimental design based generalised ANOVA

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, Souvik, E-mail: csouvik41@gmail.com; Chowdhury, Rajib, E-mail: rajibfce@iitr.ac.in

    2016-07-15

    Over the last decade, surrogate modelling technique has gained wide popularity in the field of uncertainty quantification, optimization, model exploration and sensitivity analysis. This approach relies on experimental design to generate training points and regression/interpolation for generating the surrogate. In this work, it is argued that conventional experimental design may render a surrogate model inefficient. In order to address this issue, this paper presents a novel distribution adaptive sequential experimental design (DA-SED). The proposed DA-SED has been coupled with a variant of generalised analysis of variance (G-ANOVA), developed by representing the component function using the generalised polynomial chaos expansion. Moreover, generalised analytical expressions for calculating the first two statistical moments of the response, which are utilized in predicting the probability of failure, have also been developed. The proposed approach has been utilized in predicting probability of failure of three structural mechanics problems. It is observed that the proposed approach yields accurate and computationally efficient estimate of the failure probability.

  15. Sequential experimental design based generalised ANOVA

    Science.gov (United States)

    Chakraborty, Souvik; Chowdhury, Rajib

    2016-07-01

    Over the last decade, surrogate modelling technique has gained wide popularity in the field of uncertainty quantification, optimization, model exploration and sensitivity analysis. This approach relies on experimental design to generate training points and regression/interpolation for generating the surrogate. In this work, it is argued that conventional experimental design may render a surrogate model inefficient. In order to address this issue, this paper presents a novel distribution adaptive sequential experimental design (DA-SED). The proposed DA-SED has been coupled with a variant of generalised analysis of variance (G-ANOVA), developed by representing the component function using the generalised polynomial chaos expansion. Moreover, generalised analytical expressions for calculating the first two statistical moments of the response, which are utilized in predicting the probability of failure, have also been developed. The proposed approach has been utilized in predicting probability of failure of three structural mechanics problems. It is observed that the proposed approach yields accurate and computationally efficient estimate of the failure probability.

  16. Principles of Experimental Design for Big Data Analysis.

    Science.gov (United States)

    Drovandi, Christopher C; Holmes, Christopher; McGree, James M; Mengersen, Kerrie; Richardson, Sylvia; Ryan, Elizabeth G

    2017-08-01

    Big Datasets are endemic, but are often notoriously difficult to analyse because of their size, heterogeneity and quality. The purpose of this paper is to open a discourse on the potential for modern decision theoretic optimal experimental design methods, which by their very nature have traditionally been applied prospectively, to improve the analysis of Big Data through retrospective designed sampling in order to answer particular questions of interest. By appealing to a range of examples, it is suggested that this perspective on Big Data modelling and analysis has the potential for wide generality and advantageous inferential and computational properties. We highlight current hurdles and open research questions surrounding efficient computational optimisation in using retrospective designs, and in part this paper is a call to the optimisation and experimental design communities to work together in the field of Big Data analysis.

  17. Performance of current measurement system in poloidal field power supply for Experimental Advanced Superconducting Tokamak

    Science.gov (United States)

    Liu, D. M.; Li, J.; Wan, B. N.; Lu, Z.; Wang, L. S.; Jiang, L.; Lu, C. H.; Huang, J.

    2016-11-01

    As one of the core subsystems of the Experimental Advanced Superconducting Tokamak (EAST), the poloidal field power system supplies energy to EAST's superconducting coils. To measure the converter current in the poloidal field power system, a current measurement system has been designed. The proposed measurement system is composed of a Rogowski coil and a newly designed integrator. The results of the resistor-inductor-capacitor discharge test and the converter equal current test show that the current measurement system provides good reliability and stability, and the maximum error of the proposed system is less than 1%.

  18. Design of current mirror integration ROIC for snapshot mode operation

    Science.gov (United States)

    Shanker Gupta, Hari; Kiran Kumar, A. S.; Shojaei Baghini, M.; Chakrabarti, Subhananda; Mehta, Sanjeev; Chowdhury, Arup Roy; Sharma, Dinesh K.

    2016-10-01

    Current mirror integration (CMI) read out integrated circuit (ROIC) topology provides a low input impedance to photo-detectors and provides large injection efficiency, large charge handling capacity and snapshot mode operation without in-pixel opamps. The ROIC described in this paper has been implemented with a modified current mirror circuit, with matched PMOS pairs for detector input stage and its biasing. The readout circuit has been designed for 30 × 30 μm2 pixel size, 4 × 4 array size, variable frame rate, 5 Mega pixel per second (Mpps). Experimental performance of the test chip has achieved 15 Me charge handling capacity, a high dynamic range of 83 dB, 99.8% linearity and 99.96% injection efficiency. The ROIC design has been fabricated in 3.3 V 1P6M UMC 180 nm CMOS process and tested up to 5 MHz pixel rate at room and at cryogenic temperature.

  19. Experimental design of laminar proportional amplifiers

    Science.gov (United States)

    Hellbaum, R. F.

    1976-01-01

    An experimental program was initiated at Langley Research Center to study the effects of various parameters on the design of laminar proportional beam deflection amplifiers. Matching and staging of amplifiers to obtain high-pressure gain was also studied. Variable parameters were aspect ratio, setback, control length, receiver distance, receiver width, width of center vent, and bias pressure levels. Usable pressure gains from 4 to 19 per stage can now be achieved, and five amplifiers were staged together to yield pressure gains up to 2,000,000.

  20. Direct current hybrid breakers: A design and its realization

    Science.gov (United States)

    Atmadji, Ali Mahfudz Surya

    2000-12-01

    The use of semiconductors for electric power circuit breakers instead of conventional breakers remains a utopia when designing fault current interrupters for high power networks. The major problems concerning power semiconductor circuit breakers are the excessive heat losses and their sensitivity to transients. However, conventional breakers are capable of dealing with such matters. A combination of the two methods, or so-called `hybrid breakers', would appear to be a solution; however, hybrid breakers use separate parallel branches for conducting the main current and interrupting the short-circuit current. Such breakers are intended for protecting direct current (DC) traction systems. In this thesis hybrid switching techniques for current limitation and purely solidstate current interruption are investigated for DC breakers. This work analyzes the transient behavior of hybrid breakers and compares their operations with conventional breakers and similar solid-state devices in DC systems. Therefore a hybrid breaker was constructed and tested in a specially designed high power test circuit. A vacuum breaker was chosen as the main breaker in the main conducting path; then a commutation path was connected across the vacuum breaker where it provided current limitation and interruption. The commutation path operated only during any current interruption and the process required additional circuits. These included a certain energy storage, overvoltage suppressor and commutation switch. So that when discharging this energy, a controlled counter-current injection could be produced. That counter-current opposed the main current in the breaker by superposition in order to create a forced current-zero. One-stage and two-stage commutation circuits have been treated extensively. This study project contains both theoretical and experimental investigations. A direct current shortcircuit source was constructed capable of delivering power equivalent to a fault. It supplied a direct

  1. Experimental Gravity Currents Propagating Downslope Over A Synthetic Topography

    Science.gov (United States)

    Burgos Cuevas, Andrea; Ruiz-Angulo, Angel; Palacios-Morales, Carlos

    2016-11-01

    Lock-release gravity currents are studied experimentally in order to investigate their dynamics and the mixing process between them and the ambient fluid. We produced these currents in a laboratory tank and allow them to propagate downslope first in a flat slope and then in a rough one with a synthetic topography. This topography is similar to the one of a side of a mountain near mexico's valley. Our aim is to investigate the dynamics of gravity currents as similar as possible to the mountain breezes that can develop around this valley. To the best of our knowledge, there are few experimental investigations that take into account the roughness of the slope. For each experiment, we obtain the instantaneous velocity fields using the standard piv technique. From the velocity fields, we estimate the entrainment coefficient time series. We found that this coefficient depends on the roughness of the surface where the current propagates. Besides, pressure time series were obtained in synthetic stations along the rough profile. These series showed a very clear signal of the gravity current propagating along the slope.

  2. Experimental Plans and Intensive Numerical Aided Design

    Directory of Open Access Journals (Sweden)

    Yvon Gardan

    2014-09-01

    Full Text Available This paper deals with new methods to optimize design and subsequent phases, notably in SMEs specialized in manufacturing. SMEs use numerical simulation to verify that the design meets the expectations of the specification, following the current traditional process: CAD model, simulation of its behavior, changes in the CAD model... This process suffers from a number of drawbacks: no overall multi-criteria vision, use of CAD software, by nature "constructive, not considering the overall objectives (even with integration of the parameters or with considering the downstream phases. The research centre DINCCS led several projects, relying on industrial cases to consider more efficient approaches. It is proposed to reverse this process by making intensive simulations, based on trade knowledge, before design itself. In order to plan the great number of simulations, automatically designed plan of experiences are used. We discuss the application of this approach to intensive simulations. The stakes are crucial for SMEs, particularly manufacturing ones. Using numerical simulation (optimization intensively, before setting the CAD model, they can get unexpected gains (mass, better use of the means of manufacture.... The results show that the proposed approach is a very promising new way of computer aided design..

  3. Set membership experimental design for biological systems

    Directory of Open Access Journals (Sweden)

    Marvel Skylar W

    2012-03-01

    Full Text Available Abstract Background Experimental design approaches for biological systems are needed to help conserve the limited resources that are allocated for performing experiments. The assumptions used when assigning probability density functions to characterize uncertainty in biological systems are unwarranted when only a small number of measurements can be obtained. In these situations, the uncertainty in biological systems is more appropriately characterized in a bounded-error context. Additionally, effort must be made to improve the connection between modelers and experimentalists by relating design metrics to biologically relevant information. Bounded-error experimental design approaches that can assess the impact of additional measurements on model uncertainty are needed to identify the most appropriate balance between the collection of data and the availability of resources. Results In this work we develop a bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available. This approach leverages many of the recent advances in bounded-error parameter and state estimation methods that use interval analysis to generate parameter sets and state bounds consistent with uncertain data measurements. We devise a novel approach using set-based uncertainty propagation to estimate measurement ranges at candidate time points. We then use these estimated measurements at the candidate time points to evaluate which candidate measurements furthest reduce model uncertainty. A method for quickly combining multiple candidate time points is presented and allows for determining the effect of adding multiple measurements. Biologically relevant metrics are developed and used to predict when new data measurements should be acquired, which system components should be measured and how many additional measurements should be obtained. Conclusions The practicability of our approach is illustrated with a case study. This

  4. Set membership experimental design for biological systems

    Science.gov (United States)

    2012-01-01

    Background Experimental design approaches for biological systems are needed to help conserve the limited resources that are allocated for performing experiments. The assumptions used when assigning probability density functions to characterize uncertainty in biological systems are unwarranted when only a small number of measurements can be obtained. In these situations, the uncertainty in biological systems is more appropriately characterized in a bounded-error context. Additionally, effort must be made to improve the connection between modelers and experimentalists by relating design metrics to biologically relevant information. Bounded-error experimental design approaches that can assess the impact of additional measurements on model uncertainty are needed to identify the most appropriate balance between the collection of data and the availability of resources. Results In this work we develop a bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available. This approach leverages many of the recent advances in bounded-error parameter and state estimation methods that use interval analysis to generate parameter sets and state bounds consistent with uncertain data measurements. We devise a novel approach using set-based uncertainty propagation to estimate measurement ranges at candidate time points. We then use these estimated measurements at the candidate time points to evaluate which candidate measurements furthest reduce model uncertainty. A method for quickly combining multiple candidate time points is presented and allows for determining the effect of adding multiple measurements. Biologically relevant metrics are developed and used to predict when new data measurements should be acquired, which system components should be measured and how many additional measurements should be obtained. Conclusions The practicability of our approach is illustrated with a case study. This study shows that our

  5. Experimental simulation of gravity currents in erodible bed

    Science.gov (United States)

    Bateman, A.; La Roca, M.; Medina, V.

    2009-04-01

    Gravity currents are commonly met in nature, when a flow of denser fluid moves into a less dense one. A typical example of a gravity current is given by the sea water which flows into the bottom of a river during the summer, in correspondence of the estuary, when the river's discharge attains low values. In this case, dangerous consequences can occur, because of the polluting of the aquifer caused by the salty water. Density currents also occurs in lakes and reservoirs, because of a change in temperature or because a flood, both can produce some environmental impacts that are of interest to the local water Agency of the different countries. Of particular relevance is also the interaction of the gravity current with the movement of the sediments from the bottom of the bed. The international state of the art is particularly concerned with experimental and numerical investigation on gravity currents on fixed and porous bed [1-2-3], while, to the authors' knowledge, the interaction of a gravity current with an erodible bed is still an open field of investigation. In this paper experiments concerning with the propagation of a gravity current over fixed and erodible bed are presented. The experiments, conducted at the laboratory of Hydraulics of the Universitat Politecnica de Catalunya (actually in the Prof. Bateman's blue room), were concerned with a transparent tank 2 m long, 0.2 m wide and 0.3 m deep, partly filled with salty water and partly with fresh water, up to a depth of 0.28 m. The salty water, whose density was in the range 1050John E. Simpson. Gravity Currents [3] J.J. Monaghan, R.A.F. Cas, A.M. Kos, M. Hallworth, Gravity currents descending a ramp in a stratified tank, The Journal of Fluid Mechanics, Vol. 379, 1999

  6. Current transformers with nanocrystalline alloy toroidal core: analytical, computational and experimental studies

    Directory of Open Access Journals (Sweden)

    Benedito Antonio Luciano

    2012-10-01

    Full Text Available In this paper are presented theoretical analysis and experimental results concerning the performance of toroidal cores used in current transformers. For most problems concerning transformers design, analytical methods are useful, but numerical methods provide a better understanding of the transformers electromagnetic behaviour. Numerical field solutions may be used to determine the electrical equivalent circuit parameters of toroidal core current transformers. Since the exciting current of current transformers alters the ratio and phase angle of primary and secondary currents, it is made as small as possible though the use of high permeability and low loss magnetic material in the construction of the core. According to experimental results presented in this work, in comparison with others soft magnetic materials, nanocrystalline alloys appear as the best material to be used in toroidal core for current transformers.

  7. Experimental Design for the LATOR Mission

    Science.gov (United States)

    Turyshev, Slava G.; Shao, Michael; Nordtvedt, Kenneth, Jr.

    2004-01-01

    This paper discusses experimental design for the Laser Astrometric Test Of Relativity (LATOR) mission. LATOR is designed to reach unprecedented accuracy of 1 part in 10(exp 8) in measuring the curvature of the solar gravitational field as given by the value of the key Eddington post-Newtonian parameter gamma. This mission will demonstrate the accuracy needed to measure effects of the next post-Newtonian order (near infinity G2) of light deflection resulting from gravity s intrinsic non-linearity. LATOR will provide the first precise measurement of the solar quadrupole moment parameter, J(sub 2), and will improve determination of a variety of relativistic effects including Lense-Thirring precession. The mission will benefit from the recent progress in the optical communication technologies the immediate and natural step above the standard radio-metric techniques. The key element of LATOR is a geometric redundancy provided by the laser ranging and long-baseline optical interferometry. We discuss the mission and optical designs, as well as the expected performance of this proposed mission. LATOR will lead to very robust advances in the tests of Fundamental physics: this mission could discover a violation or extension of general relativity, or reveal the presence of an additional long range interaction in the physical law. There are no analogs to the LATOR experiment; it is unique and is a natural culmination of solar system gravity experiments.

  8. Experimental Study on Current Decay Characteristics of Persistent Current HTS Magnet by Alternating Magnetic Field

    Science.gov (United States)

    Park, Young Gun; Lee, Chang Young; Hwang, Young Jin; Lee, Woo Seung; Lee, Jiho; Jo, Hyun Chul; Chung, Yoon Do; Ko, Tae Kuk

    This paper deals with a current decay characteristics of a high temperature superconducting (HTS) magnet operated in persistent current mode (PCM). In superconducting synchronous machine applications such as linear synchronous motor (LSM), the superconducting coil is designed to operate in the PCM to obtain steady magnetic field with DC transport current. This superconducting magnet operates on a direct current, but it can be exposed to alternating magnetic field due to the armature winding. When the magnet is subjected to an external time-varying magnetic field, it is possible to result in a decay of the current in PCM system due to AC loss. In this research, a PCM system with armature coil which generates time-varying magnetic field was fabricated to verify current decay characteristics by external alternating magnetic field. The current decay rate was measured by using a hall sensor as functions of amplitude and frequency of armature coil.

  9. SUSY effects in Rb: Revisited under current experimental constraints

    Science.gov (United States)

    Su, Wei; Yang, Jin Min

    2016-06-01

    In this note we revisit the SUSY effects in Rb under current experimental constraints including the LHC Higgs data, the B-physics measurements, the dark matter relic density and direct detection limits, as well as the precision electroweak data. We first perform a scan to figure out the currently allowed parameter space and then display the SUSY effects in Rb. We find that although the SUSY parameter space has been severely restrained by current experimental data, both the general MSSM and the natural-SUSY scenario can still alter Rb with a magnitude sizable enough to be observed at future Z-factories (ILC, CEPC, FCC-ee, Super Z-factory) which produce 109-1012Z-bosons. To be specific, assuming a precise measurement δRb = 2.0 ×10-5 at FCC-ee, we can probe a right-handed stop up to 530 GeV through chargino-stop loops, probe a sbottom to 850 GeV through neutralino-sbottom loops and a charged Higgs to 770 GeV through the Higgs-top quark loops for a large tan ⁡ β. The full one-loop SUSY correction to Rb can reach 1 ×10-4 in natural SUSY and 2 ×10-4 in the general MSSM.

  10. The role of experimental typography in designing logotypes

    OpenAIRE

    Pogačnik, Tadeja

    2014-01-01

    Designing logotypes is an important part of graphic design. Great logotypes are designed using custom made typefaces. Therefore, it is very important, especially for the typographic designer, to have practical experience and be up to date with all trends in the field of experimental typefaces design, also called experimental typography. In my thesis statement, I carefully examined the problems of experimental typography - which allows more creative and free typography designing for different ...

  11. Design Aspects and Test of an Inductive Fault Current Limiter

    Directory of Open Access Journals (Sweden)

    Arsénio Pedro

    2014-05-01

    Full Text Available Magnetic shielding inductive fault current limiters with high temperature superconducting tapes are considered as emerging devices that provide technology for the advent of modern power grids. The development of such limiters requires magnetic iron cores and leads to several design challenges regarding the constitutive parts of the limiter, namely the primary and secondary windings. Preliminary tests in a laboratory scale prototype have been carried out considering an assembly designed for simplicity in which the optimization of the magnetic coupling between the primary and secondary was not the main focus. This work addresses the design configuration of an inductive current limiter prototype regarding the assembly of the primary and secondary windings in the core. The prototype is based on a closed magnetic core wound by a primary, built from a normal electric conductor, and a short-circuited secondary, built from first generation superconducting tape. Four different design configurations are considered. Through experimental tests, the performance of such prototype is discussed and compared, in terms of normal and fault operation regimes. The results show that all the configurations assure effective magnetic shielding at normal operation regime, however, at fault operation regime, there are differences among configurations.

  12. Virtual smile design systems: a current review.

    Science.gov (United States)

    Zimmermann, Moritz; Mehl, Albert

    2015-01-01

    In the age of digital dentistry, virtual treatment planning is becoming an increasingly important element of dental practice. Thanks to new technological advances in the computer- assisted design and computer-assisted manufacturing (CAD/CAM) of dental restorations, predictable interdisciplinary treatment using the backward planning approach appears useful and feasible. Today, a virtual smile design can be used as the basis for creating an esthetic virtual setup of the desired final result. The virtual setup, in turn, is used to plan further treatment steps in an interdisciplinary team approach, and communicate the results to the patient. The smile design concept and the esthetic analyses required for it are described in this article. We include not only a step-by-step description of the virtual smile design workflow, but also describe and compare the several available smile design options and systems. Subsequently, a brief discussion of the advantages and limitations of virtual smile design is followed by a section on different ways to integrate a two-dimensional (2D) smile design into the digital three-dimensional (3D) workflow. New technological developments are also described, such as the integration of smile designs in digital face scans, and 3D diagnostic follow-up using intraoral scanners.

  13. Optimizing an experimental design for an electromagnetic experiment

    Science.gov (United States)

    Roux, Estelle; Garcia, Xavier

    2013-04-01

    Most of geophysical studies focus on data acquisition and analysis, but another aspect which is gaining importance is the discussion on acquisition of suitable datasets. This can be done through the design of an optimal experiment. Optimizing an experimental design implies a compromise between maximizing the information we get about the target and reducing the cost of the experiment, considering a wide range of constraints (logistical, financial, experimental …). We are currently developing a method to design an optimal controlled-source electromagnetic (CSEM) experiment to detect a potential CO2 reservoir and monitor this reservoir during and after CO2 injection. Our statistical algorithm combines the use of linearized inverse theory (to evaluate the quality of one given design via the objective function) and stochastic optimization methods like genetic algorithm (to examine a wide range of possible surveys). The particularity of our method is that it uses a multi-objective genetic algorithm that searches for designs that fit several objective functions simultaneously. One main advantage of this kind of technique to design an experiment is that it does not require the acquisition of any data and can thus be easily conducted before any geophysical survey. Our new experimental design algorithm has been tested with a realistic one-dimensional resistivity model of the Earth in the region of study (northern Spain CO2 sequestration test site). We show that a small number of well distributed observations have the potential to resolve the target. This simple test also points out the importance of a well chosen objective function. Finally, in the context of CO2 sequestration that motivates this study, we might be interested in maximizing the information we get about the reservoir layer. In that case, we show how the combination of two different objective functions considerably improve its resolution.

  14. Learning design: reflections upon the current landscape

    Directory of Open Access Journals (Sweden)

    Brock Craft

    2012-08-01

    Full Text Available The mounting wealth of open and readily available information and the accelerated evolution of social, mobile and creative technologies call for a re-conceptualisation of the role of educators: from providers of knowledge to designers of learning. This call is reverberated by the rising trend of research in learning design (LD. Addressing this, the Art and Science of Learning Design workshop brought together leading voices in the field, and provided a forum for discussing its key issues. It focused on three major themes: (1 practices, methods and methodologies, (2 tools and resources and (3 theoretical frameworks. This paper proposes a definition of LD, reviews the main contributions from the workshop, and suggests some challenges for future research.

  15. Manifold Regularized Experimental Design for Active Learning.

    Science.gov (United States)

    Zhang, Lining; Shum, Hubert P H; Shao, Ling

    2016-12-02

    Various machine learning and data mining tasks in classification require abundant data samples to be labeled for training. Conventional active learning methods aim at labeling the most informative samples for alleviating the labor of the user. Many previous studies in active learning select one sample after another in a greedy manner. However, this is not very effective because the classification models has to be retrained for each newly labeled sample. Moreover, many popular active learning approaches utilize the most uncertain samples by leveraging the classification hyperplane of the classifier, which is not appropriate since the classification hyperplane is inaccurate when the training data are small-sized. The problem of insufficient training data in real-world systems limits the potential applications of these approaches. This paper presents a novel method of active learning called manifold regularized experimental design (MRED), which can label multiple informative samples at one time for training. In addition, MRED gives an explicit geometric explanation for the selected samples to be labeled by the user. Different from existing active learning methods, our method avoids the intrinsic problems caused by insufficiently labeled samples in real-world applications. Various experiments on synthetic datasets, the Yale face database and the Corel image database have been carried out to show how MRED outperforms existing methods.

  16. Current Trends in Wireless Sensor Network Design

    OpenAIRE

    Neha Jain; Agrawal, Dharma P.

    2005-01-01

    The self-organizing nature of sensor networks, their autonomous operation and potential architectural alternatives make them suitable for different data-centric applications. Their wider acceptance seems to be rising on the horizon. In this article, we present an overview of the current state of the art in the field of wireless sensor networks. We also present various open research issues and provide an insight about the latest developments that need to be explored in greater depth that could...

  17. Experimental Investigation of Turbulence Specifications of Turbidity Currents

    Directory of Open Access Journals (Sweden)

    B Firoozabadi

    2010-01-01

    Full Text Available The present study investigates the turbulence characteristic of turbidity current experimentally. The three-dimensional Acoustic-Doppler Velocimeter (ADV was used to measure the instantaneous velocity and characteristics of the turbulent flow. The experiments were conducted in a three-dimensional channel for different discharge flows, concentrations, and bed slopes. Results are expressed at various distances from the inlet, for all flow rates, slopes and concentrations as the distribution of turbulence energy, Reynolds stress and the turbulent intensity. It was concluded that the maximum turbulence intensity happens in both the interface and near the wall. Also, it was observed that the turbulence intensity reaches its minimum where maximum velocity occurs.

  18. Autonomous entropy-based intelligent experimental design

    Science.gov (United States)

    Malakar, Nabin Kumar

    2011-07-01

    The aim of this thesis is to explore the application of probability and information theory in experimental design, and to do so in a way that combines what we know about inference and inquiry in a comprehensive and consistent manner. Present day scientific frontiers involve data collection at an ever-increasing rate. This requires that we find a way to collect the most relevant data in an automated fashion. By following the logic of the scientific method, we couple an inference engine with an inquiry engine to automate the iterative process of scientific learning. The inference engine involves Bayesian machine learning techniques to estimate model parameters based upon both prior information and previously collected data, while the inquiry engine implements data-driven exploration. By choosing an experiment whose distribution of expected results has the maximum entropy, the inquiry engine selects the experiment that maximizes the expected information gain. The coupled inference and inquiry engines constitute an autonomous learning method for scientific exploration. We apply it to a robotic arm to demonstrate the efficacy of the method. Optimizing inquiry involves searching for an experiment that promises, on average, to be maximally informative. If the set of potential experiments is described by many parameters, the search involves a high-dimensional entropy space. In such cases, a brute force search method will be slow and computationally expensive. We develop an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment. This helps to reduce the number of computations necessary to find the optimal experiment. We also extended the method of maximizing entropy, and developed a method of maximizing joint entropy so that it could be used as a principle of collaboration between two robots. This is a major achievement of this thesis, as it allows the information-based collaboration between two robotic units towards a same

  19. Recent experimental results of KSTAR RF heating and current drive

    Energy Technology Data Exchange (ETDEWEB)

    Wang, S. J., E-mail: sjwang@nfri.re.kr; Kim, J.; Jeong, J. H.; Kim, H. J.; Joung, M.; Bae, Y. S.; Kwak, J. G. [National Fusion Research Institute, Daejoen, 305-806 (Korea, Republic of)

    2015-12-10

    The overview of KSTAR activities on ICRH, LHCD and ECH/CD including the last experimental results and future plan aiming for long-pulse high-beta plasma will be presented. Recently we achieved reasonable coupling of ICRF power to H-mode plasma through several efforts to increase system reliability. Power balance will be discussed on this experiment. LHCD is still struggling in the low power regime. Review of antenna spectrum for the higher coupling in H-mode plasma will be tried. ECH/CD provides 41 sec, 0.8 MW of heating power to support high-performance long-pulse discharge. Also, 170 GHz ECH system is integrated with the Plasma Control System (PCS) for the feedback controlling of NTM. Status and plan of ECH/CD will be discussed. Finally, helicon current drive is being prepared for the next stage of KSTAR operation. The hardware preparation and the calculation results of helicon current drive in KSTAR plasma will be discussed.

  20. Design and optimization of a flexible arrayed eddy current sensor

    Science.gov (United States)

    Sun, Zhenguo; Cai, Dong; Zou, Cheng; Zhang, Wenzeng; Chen, Qiang

    2017-04-01

    The inspection of the hollow axle inner surfaces is a key process to guarantee the safety of high-speed trains. A novel flexible arrayed eddy current sensor was developed to improve the reliability of the non-destructive testing of the hollow axle inner surfaces, whose main innovative aspect was the new design of excitation/sensing traces to achieve a differential and arrayed configuration. Only two independent excitation traces were used in the sensor to induce eddy currents, which can be detected by 16 differential sensing elements. The lift-off effects and the influence of the excitation frequency and geometrical parameters of the proposed sensor was investigated and presented in this paper. Finite element models were built to analyze the effects of each parameter on the sensor response amplitude. Experimental validations were conducted using a representative set of sensors. Results from experiments and simulations were consistent with each other, which showed that the sensor design can substantially suppress the lift-off effects and modifications of the studied parameters can substantially improve the sensor performance.

  1. Technological issues and experimental design of gene association studies.

    Science.gov (United States)

    Distefano, Johanna K; Taverna, Darin M

    2011-01-01

    Genome-wide association studies (GWAS), in which thousands of single-nucleotide polymorphisms (SNPs) spanning the genome are genotyped in individuals who are phenotypically well characterized, -currently represent the most popular strategy for identifying gene regions associated with common -diseases and related quantitative traits. Improvements in technology and throughput capability, development of powerful statistical tools, and more widespread acceptance of pooling-based genotyping approaches have led to greater utilization of GWAS in human genetics research. However, important considerations for optimal experimental design, including selection of the most appropriate genotyping platform, can enhance the utility of the approach even further. This chapter reviews experimental and technological issues that may affect the success of GWAS findings and proposes strategies for developing the most comprehensive, logical, and cost-effective approaches for genotyping given the population of interest.

  2. ITER (International Thermonuclear Experimental Reactor) current drive and heating physics

    Energy Technology Data Exchange (ETDEWEB)

    Nevins, W.M.; Lindquist, W. (Lawrence Livermore National Lab., CA (USA)); Fujisawa, N.; Kimura, H. (Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan)); Hopman, H.; Rebuffi, L.; Wegrowe, J.G. (Max-Planck-Institut fuer Plasmaphysik, Garching (Germany, F.R.). NET Design Team); Parail, V.; Vdovin, V. (Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow (USSR). Inst. Atomnoj Ehn

    1990-01-01

    The ITER Current Drive and Heating (CD H) systems are required for: Ionization and current initiation; Non-inductive current ramp-up assist; Heating of the plasma; Steady-state operation with full non-inductive current drive; Current profile control; and Burn control by modulation of the auxiliary power. Steady-state current drive is the most demanding requirement, so this has driven the choice of the ITER current drive and heating systems.

  3. Development of the Biological Experimental Design Concept Inventory (BEDCI)

    OpenAIRE

    2014-01-01

    Interest in student conception of experimentation inspired the development of a fully validated 14-question inventory on experimental design in biology (BEDCI) by following established best practices in concept inventory (CI) design. This CI can be used to diagnose specific examples of non–expert-like thinking in students and to evaluate the success of teaching strategies that target conceptual changes. We used BEDCI to diagnose non–expert-like student thinking in experimental design at the p...

  4. Power Analysis Tutorial for Experimental Design Software

    Science.gov (United States)

    2014-11-01

    Details ............................................................ D-1 Appendix E – JMP Monte Carlo Simulation Script...freedom for error. • In Design Expert, when constructing a design, you are asked for delta and sigma . The default model for power analysis is...Designed Experiments. Third Edition. New York: John Wiley and Sons, 2009. 12. Muthen, Linda, and Bengt Muthen. “How to Use a Monte Carlo Study to

  5. Experimental design in analytical chemistry--part II: applications.

    Science.gov (United States)

    Ebrahimi-Najafabadi, Heshmatollah; Leardi, Riccardo; Jalali-Heravi, Mehdi

    2014-01-01

    This paper reviews the applications of experimental design to optimize some analytical chemistry techniques such as extraction, chromatography separation, capillary electrophoresis, spectroscopy, and electroanalytical methods.

  6. Beyond (eco)design: current approaches to sustainable packaging design

    NARCIS (Netherlands)

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for marketi

  7. Beyond (eco)design: current approaches to sustainable packaging design

    NARCIS (Netherlands)

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for

  8. Experimental design schemes for learning Boolean network models

    Science.gov (United States)

    Atias, Nir; Gershenzon, Michal; Labazin, Katia; Sharan, Roded

    2014-01-01

    Motivation: A holy grail of biological research is a working model of the cell. Current modeling frameworks, especially in the protein–protein interaction domain, are mostly topological in nature, calling for stronger and more expressive network models. One promising alternative is logic-based or Boolean network modeling, which was successfully applied to model signaling regulatory circuits in human. Learning such models requires observing the system under a sufficient number of different conditions. To date, the amount of measured data is the main bottleneck in learning informative Boolean models, underscoring the need for efficient experimental design strategies. Results: We developed novel design approaches that greedily select an experiment to be performed so as to maximize the difference or the entropy in the results it induces with respect to current best-fit models. Unique to our maximum difference approach is the ability to account for all (possibly exponential number of) Boolean models displaying high fit to the available data. We applied both approaches to simulated and real data from the EFGR and IL1 signaling systems in human. We demonstrate the utility of the developed strategies in substantially improving on a random selection approach. Our design schemes highlight the redundancy in these datasets, leading up to 11-fold savings in the number of experiments to be performed. Availability and implementation: Source code will be made available upon acceptance of the manuscript. Contact: roded@post.tau.ac.il PMID:25161232

  9. Conceptual design report, CEBAF basic experimental equipment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-04-13

    The Continuous Electron Beam Accelerator Facility (CEBAF) will be dedicated to basic research in Nuclear Physics using electrons and photons as projectiles. The accelerator configuration allows three nearly continuous beams to be delivered simultaneously in three experimental halls, which will be equipped with complementary sets of instruments: Hall A--two high resolution magnetic spectrometers; Hall B--a large acceptance magnetic spectrometer; Hall C--a high-momentum, moderate resolution, magnetic spectrometer and a variety of more dedicated instruments. This report contains a short description of the initial complement of experimental equipment to be installed in each of the three halls.

  10. Beyond (eco)design: current approaches to sustainable packaging design

    OpenAIRE

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for marketing reasons. This is a rather guild-based approach that, if taken to extremes, would lead to complete elimination of packaging, or at most a quintessential brown paper bag. In industry reality thoug...

  11. Design of an Experimental PCM Solar Tank

    Energy Technology Data Exchange (ETDEWEB)

    Szabo, Istvan Peter

    2010-09-15

    The one of the most important part of a solar collector system is the solar tank. The relevant type and capacity of the solar tank is a requirement of the good operation of the system. According the current architectural tendencies the boiler rooms are smaller, so the putting of the currently available solar tanks is very difficult. It is necessary to store the energy in a little space. The solution of the problem is the solar tank particularly filled with phase change material.

  12. DESIGN NOTE: A very high output resistance current source

    Science.gov (United States)

    Hayatleh, K.; Terzopoulos, N.; Hart, B. L.

    2007-01-01

    The vertical stacking of two identical sub-circuits—improved versions of a bipolar transistor configuration proposed by Baxandall and Swallow—driven by dual output current mirrors, facilitates the design of a current generator producing a direct current of 1 mA with an incremental output resistance exceeding 200 GΩ.

  13. Design, experimental verification, and analysis of a 1.8-V-input-range voltage-to-current converter using source degeneration for low-noise multimodal CMOS biosensor array

    Science.gov (United States)

    Niitsu, Kiichi; Ikeda, Kei; Muto, Keita; Nakazato, Kazuo

    2017-01-01

    A multimodal complementary metal-oxide semiconductor (CMOS) biosensor array manufactured using measurement methods such as potentiometry, amperometry, and impedimetry improves its cost competitiveness and measurement accuracy. In addition, it provides a wider range of application because it can obtain signals from multiple aspects. To develop high-signal-to-noise ratio (SNR) multimodal biosensor arrays, time-domain current integration was proposed in the literature and found to be effective. In addition to amperometry and impedimetry, it is possible to perform current integration using the potentiometry output by employing a voltage-to-current converter (VCC). However, a conventional VCC with a fixed transconductance mode does not provide a sufficient input range (measured results successfully demonstrate that the input range was enhanced from 0.6 to 1.8 V. Autonomous current limitation was also confirmed. The measured total input-referred noise was 0.445 mV (from 10 Hz to 10 kHz, assuming current integration at every 1 ms).

  14. Critical current measurement for design of HTS DC power cables

    Science.gov (United States)

    Watanabe, Hirofumi

    2017-02-01

    Critical currents of HTS DC power cables were calculated. In the calculation a relationship between critical current density and magnetic flux density proposed by Gömöry et al. [1] was used and the parameters used in the relationship were obtained by the critical current measurements with respect to the external magnetic field for a sample of the HTS tape. Numerical models of cables were composed and their critical currents were calculated, which showed the strong dependence on the arrangement of the HTS tapes in the cable. Critical current measurements of model cables assembled based on the calculations showed that the measured critical currents also depended on the arrangement of the HTS tapes strongly. The calculated results were compared with the experimental results, which showed that the experimental results agreed well with the calculated results.

  15. Experimental Investigation of a Direct Methanol Fuel Cell with Hilbert Fractal Current Collectors

    Directory of Open Access Journals (Sweden)

    Jing-Yi Chang

    2014-01-01

    Full Text Available The Hilbert curve is a continuous type of fractal space-filling curve. This fractal curve visits every point in a square grid with a size of 2×2, 4×4, or any other power of two. This paper presents Hilbert fractal curve application to direct methanol fuel cell (DMFC current collectors. The current collectors are carved following first, second, and third order Hilbert fractal curves. These curves give the current collectors different free open ratios and opening perimeters. We conducted an experimental investigation into DMFC performance as a function of the free open ratio and opening perimeter on the bipolar plates. Nyquist plots of the bipolar plates are made and compared using electrochemical impedance spectroscopy (EIS experiments to understand the phenomena in depth. The results obtained in this paper could be a good reference for future current collector design.

  16. The Implications of "Contamination" for Experimental Design in Education

    Science.gov (United States)

    Rhoads, Christopher H.

    2011-01-01

    Experimental designs that randomly assign entire clusters of individuals (e.g., schools and classrooms) to treatments are frequently advocated as a way of guarding against contamination of the estimated average causal effect of treatment. However, in the absence of contamination, experimental designs that randomly assign intact clusters to…

  17. Development of the Biological Experimental Design Concept Inventory (BEDCI)

    Science.gov (United States)

    Deane, Thomas; Nomme, Kathy; Jeffery, Erica; Pollock, Carol; Birol, Gulnur

    2014-01-01

    Interest in student conception of experimentation inspired the development of a fully validated 14-question inventory on experimental design in biology (BEDCI) by following established best practices in concept inventory (CI) design. This CI can be used to diagnose specific examples of non-expert-like thinking in students and to evaluate the…

  18. A framework for efficient process development using optimal experimental designs

    NARCIS (Netherlands)

    Ven, P. van de; Bijlsma, S.; Gout, E.; Voort Maarschalk, K. van der; Thissen, U.

    2011-01-01

    Introduction: The aim of this study was to develop and demonstrate a framework assuring efficient process development using fewer experiments than standard experimental designs. Methods: A novel optimality criterion for experimental designs (Iw criterion) is defined that leads to more efficient proc

  19. Experimental design for drifting buoy Lagrangian test

    Science.gov (United States)

    Saunders, P. M.

    1975-01-01

    A test of instrumentation fabricated to measure the performance of a free drifting buoy as a (Lagrangian) current meter is described. Specifically it is proposed to distinguish between the trajectory of a drogued buoy and the trajectory of the water at the level of the drogue by measuring the flow relative to the drogue.

  20. Research designs for experimental single-case studies

    Directory of Open Access Journals (Sweden)

    Ralf Spieß

    2012-09-01

    Full Text Available This overview describes the most important designs for single case experimental studies, which are ABAB-design, multiple baseline design, alternating treatments design and changing criterion design. The logic of experimental control in single case studies is explained and it is described, how these different designs are able to provide internal validity and enable causal interpretations of intervention outcome. An important precondition of valid interpretation is objective and reliable data assessment. Data evaluation by visual inspection is explained and several methods of statistical data analysis are discussed. To establish generability across persons, situations, and settings, the importance of replication studies is highlighted.

  1. Experimental study of blockage of monochromatic waves by counter currents

    NARCIS (Netherlands)

    Suastika, I.K.

    1999-01-01

    Blockage of waves by a current can occur if waves are propagating on a spatially varying opposing current in which the velocity is increasing in the wave propagation direction. The ongoing waves become shorter and steeper while they are propagating against the current. Blocking occurs at the

  2. Autism genetics: Methodological issues and experimental design.

    Science.gov (United States)

    Sacco, Roberto; Lintas, Carla; Persico, Antonio M

    2015-10-01

    Autism is a complex neuropsychiatric disorder of developmental origin, where multiple genetic and environmental factors likely interact resulting in a clinical continuum between "affected" and "unaffected" individuals in the general population. During the last two decades, relevant progress has been made in identifying chromosomal regions and genes in linkage or association with autism, but no single gene has emerged as a major cause of disease in a large number of patients. The purpose of this paper is to discuss specific methodological issues and experimental strategies in autism genetic research, based on fourteen years of experience in patient recruitment and association studies of autism spectrum disorder in Italy.

  3. Irradiation Design for an Experimental Murine Model

    Science.gov (United States)

    Ballesteros-Zebadúa, P.; Lárraga-Gutierrez, J. M.; García-Garduño, O. A.; Rubio-Osornio, M. C.; Custodio-Ramírez, V.; Moreno-Jimenez, S.; Suarez-Campos, J. E.; Paz, C.; Celis, M. A.

    2010-12-01

    In radiotherapy and stereotactic radiosurgery, small animal experimental models are frequently used, since there are still a lot of unsolved questions about the biological and biochemical effects of ionizing radiation. This work presents a method for small-animal brain radiotherapy compatible with a dedicated 6MV Linac. This rodent model is focused on the research of the inflammatory effects produced by ionizing radiation in the brain. In this work comparisons between Pencil Beam and Monte Carlo techniques, were used in order to evaluate accuracy of the calculated dose using a commercial planning system. Challenges in this murine model are discussed.

  4. Split-plot designs for multistage experimentation

    DEFF Research Database (Denmark)

    Kulahci, Murat; Tyssedal, John

    2016-01-01

    at the same time will be more efficient. However, there have been only a few attempts in the literature to provide an adequate and easy-to-use approach for this problem. In this paper, we present a novel methodology for constructing two-level split-plot and multistage experiments. The methodology is based...... be accommodated in each stage. Furthermore, split-plot designs for multistage experiments with good projective properties are also provided....

  5. Information measures in nonlinear experimental design

    Science.gov (United States)

    Niple, E.; Shaw, J. H.

    1980-01-01

    Some different approaches to the problem of designing experiments which estimate the parameters of nonlinear models are discussed. The assumption in these approaches that the information in a set of data can be represented by a scalar is criticized, and the nonscalar discrimination information is proposed as the proper measure to use. The two-step decay example in Box and Lucas (1959) is used to illustrate the main points of the discussion.

  6. Experimental Study on Current-Driven Domain Wall Motion

    Science.gov (United States)

    Ono, T.; Yamaguchi, A.; Tanigawa, H.; Yano, K.; Kasai, S.

    2006-06-01

    Current-driven domain wall (DW) motion for a well-defined single DW in a micro-fabricated magnetic wire with submicron width was investigated by real-space observation with magnetic force microscopy. Magnetic force microscopy visualizes that a single DW introduced in a wire is displaced back and forth by positive and negative pulsed-current, respectively. Effect of the Joule heating, reduction of the threshold current density by shape control, and magnetic ratchet effect are also presented.

  7. Human Factors Experimental Design and Analysis Reference

    Science.gov (United States)

    2007-07-01

    1) • Box Correction for Repeated Measures (Box, 1954) – Adjusted F Table – F[(k-1)ε, (n-1)(k-1)ε] – Imhof (1962) Table for Small Sample Size (nɡ...1954) provided an adjusted F tabled value based on the value of ε as shown in the middle of this slide. Alternatively, the Imhof (1962) Table is...freedom from sample data in randomized block and split-plot designs. Journal of Educational Statistics, 1, 69-82. Imhof , J.P. (1962). Testing the

  8. Design and Experimental Implementation of Bipedal robot

    OpenAIRE

    Sreejith C; Sreeshma K

    2012-01-01

    Biped robots have better mobility than conventional wheeled robots, but they tend to tip over easily. To be able to walk stably in various environments, such as on rough terrain, up and down slopes, or in regions containing obstacles, it is necessary for the robot to adapt to the ground conditions with a foot motion, and maintain its stability with a torso motion. In this paper, we first formulate the design and walking pattern for a bipedal robot and then a kicking robot has been developed f...

  9. Experimental study of the dynamics of a thin current sheet

    Science.gov (United States)

    Gekelman, W.; DeHaas, T.; Van Compernolle, B.; Daughton, W.; Pribyl, P.; Vincena, S.; Hong, D.

    2016-05-01

    Many plasmas in natural settings or in laboratory experiments carry currents. In magnetized plasmas the currents can be narrow field-aligned filaments as small as the electron inertial length ≤ft(\\tfrac{c}{{ω }pe}\\right) in the transverse dimension or fill the entire plasma column. Currents can take the form of sheets, again with the transverse dimension the narrow one. Are laminar sheets of electric current in a magnetized plasma stable? This became an important issue in the 1960s when current-carrying plasmas became key in the quest for thermonuclear fusion. The subject is still under study today. The conditions necessary for the onset for tearing are known, the key issue is that of the final state. Is there a final state? One possibility is a collection of stable tubes of current. On the other hand, is the interaction between the current filaments which are the byproduct endless, or does it go on to become chaotic? The subject of three-dimensional current systems is intriguing, rich in a variety of phenomena on multiple scale sizes and frequencies, and relevant to fusion studies, solar physics, space plasmas and astrophysical phenomena. In this study a long (δz = 11 m) and narrow (δx = 1 cm, δy = 20 cm) current sheet is generated in a background magnetoplasma capable of supporting Alfvén waves. The current is observed to rapidly tear into a series of magnetic islands when viewed in a cross-sectional plane, but they are in essence three-dimensional flux ropes. At the onset of the current, magnetic field line reconnection is observed between the flux ropes. The sheet on the whole is kink-unstable, and after kinking exhibits large-scale, low-frequency (f ≪ f ci ) rotation about the background field with an amplitude that grows with distance from the source of the current. Three-dimensional data of the magnetic and electric fields is acquired throughout the duration of the experiment and the parallel resistivity is derived from it. The parallel

  10. On experimentation across science, design and society

    DEFF Research Database (Denmark)

    Boris, Stefan Darlan

    2016-01-01

    . This is something, which is becoming increasingly relevant, as landscape architects and urban planners today have to address the challenges confronting urbanism due to the continued entanglement of urbanisation and anthropogenic processes. These are challenges where the act of destabilizing dichotomies (inside......The article describes how the principal idea behind the landscape laboratories has been to develop a 1:1 platform where researchers, practitioners and lay people can meet and cooperate on the development and testing of new design concepts for establishing and managing urban landscapes....../outside, natural/manmade, etc.) is one out of several reasons for not only continuing but also strengthening the landscape laboratories as testing grounds for future urban landscapes and green spaces in the Anthropocene....

  11. As it happens: current directions in experimental evolution.

    Science.gov (United States)

    Bataillon, Thomas; Joyce, Paul; Sniegowski, Paul

    2013-02-23

    Recent decades have seen a significant rise in studies in which evolution is observed and analysed directly-as it happens-under replicated, controlled conditions. Such 'experimental evolution' approaches offer a degree of resolution of evolutionary processes and their underlying genetics that is difficult or even impossible to achieve in more traditional comparative and retrospective analyses. In principle, experimental populations can be monitored for phenotypic and genetic changes with any desired level of replication and measurement precision, facilitating progress on fundamental and previously unresolved questions in evolutionary biology. Here, we summarize 10 invited papers in which experimental evolution is making significant progress on a variety of fundamental questions. We conclude by briefly considering future directions in this very active field of research, emphasizing the importance of quantitative tests of theories and the emerging role of genome-wide re-sequencing.

  12. 10 simple rules for best experimental design in ecology

    OpenAIRE

    Sajadi, Farwa

    2016-01-01

    A quick set of rules on how best to execute an experimental design in ecology. From having a clear hypothesis to obtaining accurate statistics, this guide will help make sure authors are on the right track before publishing. The 10 simple rules are based on articles written to help readers and editors learn more about experimental design and how to avoid any unseeable pitfalls. These rules act as a checklist for authors to go through to make sure they have created the best experimental design...

  13. An Exposition of Current Mobile Learning Design Guidelines and Frameworks

    Science.gov (United States)

    Teall, Ed; Wang, Minjuan; Callaghan, Vic; Ng, Jason W. P.

    2014-01-01

    As mobile devices with wireless access become more readily available, learning delivered via mobile devices of all types must be designed to ensure successful learning. This paper first examines three questions related to the design of mobile learning: 1) what mobile learning (m-learning) guidelines can be identified in the current literature, 2)…

  14. An Exposition of Current Mobile Learning Design Guidelines and Frameworks

    Science.gov (United States)

    Teall, Ed; Wang, Minjuan; Callaghan, Vic; Ng, Jason W. P.

    2014-01-01

    As mobile devices with wireless access become more readily available, learning delivered via mobile devices of all types must be designed to ensure successful learning. This paper first examines three questions related to the design of mobile learning: 1) what mobile learning (m-learning) guidelines can be identified in the current literature, 2)…

  15. High performance predictive current control of a three phase VSI: An experimental assessment

    Indian Academy of Sciences (India)

    Vikas Kumar; Prerna Gaur; A P Mittal

    2014-12-01

    Delay has a significant role to play in the implementation of the predictive current control scheme as large amount of calculations are involved. Compensating delay in the predictive current controller design can lead to an improved load current total harmonic distortion (THD) and also an increased switching frequency. Minimization of switching frequency while maintaining the lower value of load current THD requires multiple objective optimization which is achieved by optimizing a single objective function, constructed using weighting factors as a linear combination of individual objective function. The effect of weighting factor on the switching frequency minimization and the current tracking error with delay compensation for the two level voltage source inverter (VSI) are investigated in this paper. The outcomes of the predictive current control using an optimized weighting factor which is calculated using branch and bound algorithm with the delay compensation are compared with the PWM based current control scheme. The experimental tests are conducted on a 2.2 kW VSI to verify the simulation observations.

  16. Numerical taxonomy of maize landraces: comparison between experimental designs

    OpenAIRE

    1989-01-01

    [EN] Seventy three maize (Zea mays L.) landraces from Northwestern Spain were grown according to two different experimental design.The first one (design A) was a randomized complete blocks design with two replications per trial at two locations for two years. The second design (desing B) is simpler than the first one: the populations were grown at one location without replications for three years. Numerical taxonomy of these landraces was made according to results of the field trials u...

  17. Simultaneous optimal experimental design for in vitro binding parameter estimation.

    Science.gov (United States)

    Ernest, C Steven; Karlsson, Mats O; Hooker, Andrew C

    2013-10-01

    Simultaneous optimization of in vitro ligand binding studies using an optimal design software package that can incorporate multiple design variables through non-linear mixed effect models and provide a general optimized design regardless of the binding site capacity and relative binding rates for a two binding system. Experimental design optimization was employed with D- and ED-optimality using PopED 2.8 including commonly encountered factors during experimentation (residual error, between experiment variability and non-specific binding) for in vitro ligand binding experiments: association, dissociation, equilibrium and non-specific binding experiments. Moreover, a method for optimizing several design parameters (ligand concentrations, measurement times and total number of samples) was examined. With changes in relative binding site density and relative binding rates, different measurement times and ligand concentrations were needed to provide precise estimation of binding parameters. However, using optimized design variables, significant reductions in number of samples provided as good or better precision of the parameter estimates compared to the original extensive sampling design. Employing ED-optimality led to a general experimental design regardless of the relative binding site density and relative binding rates. Precision of the parameter estimates were as good as the extensive sampling design for most parameters and better for the poorly estimated parameters. Optimized designs for in vitro ligand binding studies provided robust parameter estimation while allowing more efficient and cost effective experimentation by reducing the measurement times and separate ligand concentrations required and in some cases, the total number of samples.

  18. Active Photonic Crystal Switches: Modeling, Design and Experimental Characterization

    DEFF Research Database (Denmark)

    Heuck, Mikkel; Yu, Yi; Kristensen, Philip Trøst;

    2013-01-01

    In this paper, we present recent progress in modeling, design, fabrication and experimental characterization of InP photonic crystal all-optical switches. Novel designs with increased flexibility and performance are presented, and their operation using high speed data signals is analyzed numerica......In this paper, we present recent progress in modeling, design, fabrication and experimental characterization of InP photonic crystal all-optical switches. Novel designs with increased flexibility and performance are presented, and their operation using high speed data signals is analyzed...

  19. The Use of an Experimental Design Approach to Investigate the ...

    African Journals Online (AJOL)

    The Use of an Experimental Design Approach to Investigate the Interactions of Additives ... When a conventional starting, lighting and ignition (SLI) lead acid battery is ... Typical flooded nominal 8 Ah test cells were assembled in a reverse ratio ...

  20. Current experimental situation in heavy-ion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Scott, D.K.

    1978-06-01

    A detailed survey of the present experimental situation in heavy-ion physics is presented. The discussion begins by considering the simple excitation of discrete states in elastic scattering, transfer, and compound-nucleus reactions; it then turns to more drastic perturbations of the nucleus high in the continuum through fusion, fission, and deeply inelastic scattering, and concludes with the (possibly) limiting asymptotic phenomena of relativistic heavy-ion collisions. 138 figures, 5 tables, 451 references. (RWR)

  1. Process Model Construction and Optimization Using Statistical Experimental Design,

    Science.gov (United States)

    1988-04-01

    Memo No. 88-442 ~LECTE March 1988 31988 %,.. MvAY 1 98 0) PROCESS MODEL CONSTRUCTION AND OPTIMIZATION USING STATISTICAL EXPERIMENTAL DESIGN Emmanuel...Sachs and George Prueger Abstract A methodology is presented for the construction of process models by the combination of physically based mechanistic...253-8138. .% I " Process Model Construction and Optimization Using Statistical Experimental Design" by Emanuel Sachs Assistant Professor and George

  2. Model-Based Optimal Experimental Design for Complex Physical Systems

    Science.gov (United States)

    2015-12-03

    an open-loop behavior , where no feedback is involved , and the observations from any experiment do not affect the design of other experiments...developing and refining models of physical systems. Yet experimental observations can be difficult, time- consuming , and expensive to acquire. In this...improve design and decision-making under uncertainty. Yet experimental observations can be difficult, time- consuming , and expensive to acquire. In this

  3. Experimental Design: Utilizing Microsoft Mathematics in Teaching and Learning Calculus

    Science.gov (United States)

    Oktaviyanthi, Rina; Supriani, Yani

    2015-01-01

    The experimental design was conducted to investigate the use of Microsoft Mathematics, free software made by Microsoft Corporation, in teaching and learning Calculus. This paper reports results from experimental study details on implementation of Microsoft Mathematics in Calculus, students' achievement and the effects of the use of Microsoft…

  4. Design Issues and Inference in Experimental L2 Research

    Science.gov (United States)

    Hudson, Thom; Llosa, Lorena

    2015-01-01

    Explicit attention to research design issues is essential in experimental second language (L2) research. Too often, however, such careful attention is not paid. This article examines some of the issues surrounding experimental L2 research and its relationships to causal inferences. It discusses the place of research questions and hypotheses,…

  5. Design Issues and Inference in Experimental L2 Research

    Science.gov (United States)

    Hudson, Thom; Llosa, Lorena

    2015-01-01

    Explicit attention to research design issues is essential in experimental second language (L2) research. Too often, however, such careful attention is not paid. This article examines some of the issues surrounding experimental L2 research and its relationships to causal inferences. It discusses the place of research questions and hypotheses,…

  6. A Bayesian experimental design approach to structural health monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Farrar, Charles [Los Alamos National Laboratory; Flynn, Eric [UCSD; Todd, Michael [UCSD

    2010-01-01

    Optimal system design for SHM involves two primarily challenges. The first is the derivation of a proper performance function for a given system design. The second is the development of an efficient optimization algorithm for choosing a design that maximizes, or nearly maximizes the performance function. In this paper we will outline how an SHM practitioner can construct the proper performance function by casting the entire design problem into a framework of Bayesian experimental design. The approach demonstrates how the design problem necessarily ties together all steps of the SHM process.

  7. Current Research in Aircraft Tire Design and Performance

    Science.gov (United States)

    Tanner, J. A.; Mccarthy, J. L.; Clark, S. K.

    1981-01-01

    A review of the tire research programs which address the various needs identified by landing gear designers and airplane users is presented. The experimental programs are designed to increase tire tread lifetimes, relate static and dynamic tire properties, establish the tire hydroplaning spin up speed, study gear response to tire failures, and define tire temperature profiles during taxi, braking, and cornering operations. The analytical programs are aimed at providing insights into the mechanisms of heat generation in rolling tires and developing the tools necessary to streamline the tire design process and to aid in the analysis of landing gear problems.

  8. Eddy Current Loss Modeling for Design of PM Generators for Wind Turbines

    NARCIS (Netherlands)

    Jassal, A.

    2014-01-01

    This thesis deals with analysis, calculation and validation of eddy current loss models for Permanent Magnet (PM) direct drive generators for wind turbines. The modelling approach is a mixed use of analytical and Finite Element (FE) methods. The models are validated experimentally and design guideli

  9. Randomizing Roaches: Exploring the "Bugs" of Randomization in Experimental Design

    Science.gov (United States)

    Wagler, Amy; Wagler, Ron

    2014-01-01

    Understanding the roles of random selection and random assignment in experimental design is a central learning objective in most introductory statistics courses. This article describes an activity, appropriate for a high school or introductory statistics course, designed to teach the concepts, values and pitfalls of random selection and assignment…

  10. Fundamentals of experimental design: lessons from beyond the textbook world

    Science.gov (United States)

    We often think of experimental designs as analogous to recipes in a cookbook. We look for something that we like and frequently return to those that have become our long-standing favorites. We can easily become complacent, favoring the tried-and-true designs (or recipes) over those that contain unkn...

  11. Experimental Design and Multiplexed Modeling Using Titrimetry and Spreadsheets

    Science.gov (United States)

    Harrington, Peter De B.; Kolbrich, Erin; Cline, Jennifer

    2002-07-01

    The topics of experimental design and modeling are important for inclusion in the undergraduate curriculum. Many general chemistry and quantitative analysis courses introduce students to spreadsheet programs, such as MS Excel. Students in the laboratory sections of these courses use titrimetry as a quantitative measurement method. Unfortunately, the only model that students may be exposed to in introductory chemistry courses is the working curve that uses the linear model. A novel experiment based on a multiplex model has been devised for titrating several vinegar samples at a time. The multiplex titration can be applied to many other routine determinations. An experimental design model is fit to titrimetric measurements using the MS Excel LINEST function to estimate concentration from each sample. This experiment provides valuable lessons in error analysis, Class A glassware tolerances, experimental simulation, statistics, modeling, and experimental design.

  12. Voltage and Current Regulators Design of Power Converters in Islanded Microgrids based on State Feedback Decoupling

    DEFF Research Database (Denmark)

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Freijedo Fernandez, Francisco Daniel

    2016-01-01

    In stand-alone microgrids based on voltage source inverters state feedback coupling between the capacitor voltage and inductor current degrades significantly the dynamics performance of voltage and current regulators. The decoupling of the controlled states is proposed, considering the limitations...... introduced by system delays. Moreover, a proportional resonant voltage controller is designed according to Nyquist criterion taking into account application requirements. Experimental tests performed in compliance with the UPS standards verify the theoretical analysis....

  13. Experimental Methodology in English Teaching and Learning: Method Features, Validity Issues, and Embedded Experimental Design

    Science.gov (United States)

    Lee, Jang Ho

    2012-01-01

    Experimental methods have played a significant role in the growth of English teaching and learning studies. The paper presented here outlines basic features of experimental design, including the manipulation of independent variables, the role and practicality of randomised controlled trials (RCTs) in educational research, and alternative methods…

  14. Wall conditioning for ITER: Current experimental and modeling activities

    Energy Technology Data Exchange (ETDEWEB)

    Douai, D., E-mail: david.douai@cea.fr [CEA, IRFM, Association Euratom-CEA, 13108 St. Paul lez Durance (France); Kogut, D. [CEA, IRFM, Association Euratom-CEA, 13108 St. Paul lez Durance (France); Wauters, T. [LPP-ERM/KMS, Association Belgian State, 1000 Brussels (Belgium); Brezinsek, S. [FZJ, Institut für Energie- und Klimaforschung Plasmaphysik, 52441 Jülich (Germany); Hagelaar, G.J.M. [Laboratoire Plasma et Conversion d’Energie, UMR5213, Toulouse (France); Hong, S.H. [National Fusion Research Institute, Daejeon 305-806 (Korea, Republic of); Lomas, P.J. [CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Lyssoivan, A. [LPP-ERM/KMS, Association Belgian State, 1000 Brussels (Belgium); Nunes, I. [Associação EURATOM-IST, Instituto de Plasmas e Fusão Nuclear, 1049-001 Lisboa (Portugal); Pitts, R.A. [ITER International Organization, F-13067 St. Paul lez Durance (France); Rohde, V. [Max-Planck-Institut für Plasmaphysik, 85748 Garching (Germany); Vries, P.C. de [ITER International Organization, F-13067 St. Paul lez Durance (France)

    2015-08-15

    Wall conditioning will be required in ITER to control fuel and impurity recycling, as well as tritium (T) inventory. Analysis of conditioning cycle on the JET, with its ITER-Like Wall is presented, evidencing reduced need for wall cleaning in ITER compared to JET–CFC. Using a novel 2D multi-fluid model, current density during Glow Discharge Conditioning (GDC) on the in-vessel plasma-facing components (PFC) of ITER is predicted to approach the simple expectation of total anode current divided by wall surface area. Baking of the divertor to 350 °C should desorb the majority of the co-deposited T. ITER foresees the use of low temperature plasma based techniques compatible with the permanent toroidal magnetic field, such as Ion (ICWC) or Electron Cyclotron Wall Conditioning (ECWC), for tritium removal between ITER plasma pulses. Extrapolation of JET ICWC results to ITER indicates removal comparable to estimated T-retention in nominal ITER D:T shots, whereas GDC may be unattractive for that purpose.

  15. EXPERIMENTAL STUDY ON BED-LOAD SEDIMENT TRANSPORT IN IRREGULAR WAVE-CURRENT COEXISTENT FIELD

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In order to evaluate bed-load sediment transport in an irregular wave-current coexistent field, a series of experiments were completed in laboratory with an irregularly oscillating tray, which was specially designed to simulate the irregular wave-current coexistent field. Experimental results are presented on the initial motion of sediment and the rates of transport over flat horizontal bed. Testing conditions included three interaction angles, 0°, 45°, 90° and six kinds of grain sizes. Four kinds (0.2mm, 0.46mm, 0.85mm and 1.3mm) were used for the tests of initial motion, while the other two kinds (0.38mm and 1.1mm) for the tests of transport rate. Comparisons between experimental results of initial motion and modified Shields curve indicate that the Shields curve is still valid for the case of irregular wave-current coexistent field. Analysis of flow regime shows that initial conditions fall within smooth-turbulent transitional region. The results of transport rate show us that net sediment transport rate can be expressed approximately as the function of the maximum bottom shear stress and mean shear stress. A dimensionless formula is proposed on the basis of mechanism "Waves erode sediments, tides transport sediments".

  16. Experimental investigation of current free double layers in helicon plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Sahu, B. B. [Department of Applied Sciences and Humanities, Dronacharya College of Engineering, Gurgaon 123506 (India); Tarey, R. D. [Department of Physics, Indian Institute of Technology, New Delhi 110016 (India); Ganguli, A. [Centre for Energy Studies, Indian Institute of Technology, New Delhi 110016 (India)

    2014-02-15

    The paper presents investigations of current free double layer (CFDL) that forms in helicon plasmas. In contrast to the other work reporting on the same subject, in the present investigations the double layer (DL) forms in a mirror-like magnetic field topology. The RF compensated Langmuir probe measurements show multiple DLs, which are in connection with, the abrupt fall of densities along with potential drop of about 24 V and 18 V. The DLs strengths (e ΔV{sub p})/(k T{sub e}) are about 9.5 and 6, and the corresponding widths are about 6 and 5 D lengths. The potential drop is nearly equal to the thermal anisotropies between the two plasma regions forming the DL, which is present in the plateau region of mirror, unlike the earlier studies on the DL formation in the region of strong gradients in the magnetic field. Also, it presents a qualitative discussion on the mechanism of DL formation.

  17. Design of BEPC Ⅱ bunch current monitor system

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lei; MA Hui-Zhou; YUE Jun-Hui; LEI Ge; CAO Jian-She; MA Li

    2008-01-01

    BEPC Ⅱ is an electron-positron collider designed to run under multi-bunches and high beam current condition. The accelerator consists of an electron ring, a positron ring and a linear injector. In order to achieve the target luminosity and implement the equal bunch charge injection, the Bunch Current Monitor (BCM)system is built on BEPC Ⅱ. The BCM system consists of three parts: the front-end circuit, the bunch current acquisition system and the bucket selection system. The control software of BCM is based on VxWorks and EPICS. With the help of BCM system, the bunch current in each bucket can be monitored in the Central Control Room. The BEPC Ⅱ timing system can also use the bunch current database to decide which bucket needs to refill to implement "top-off" injection.

  18. Design and current progress of the Apollon 10 PW project

    Institute of Scientific and Technical Information of China (English)

    J.P.Zou; C.Le Blanc; D.N.Papadopoulos; G.Chériaux; P.Georges; G.Mennerat; F.Druon; L.Lecherbourg; A.Pellegrina; P.Ramirez; F.Giambruno; A.Fréneaux; F.Leconte; D.Badarau; J.M.Boudenne; D.Fournet; T.Valloton; J.L.Paillard; J.L.Veray; M.Pina; P.Monot; J.P.Chambaret; P.Martin; F.Mathieu; P.Audebert; F.Amiranoff

    2015-01-01

    The objective of the Apollon project is the generation of 10 PW peak power pulses of 15 fs at 1 shot/minute. In this paper the Apollon facility design, the technological challenges and the current progress of the project will be presented.

  19. Design and Experimental Study on Spinning Solid Rocket Motor

    Science.gov (United States)

    Xue, Heng; Jiang, Chunlan; Wang, Zaicheng

    The study on spinning solid rocket motor (SRM) which used as power plant of twice throwing structure of aerial submunition was introduced. This kind of SRM which with the structure of tangential multi-nozzle consists of a combustion chamber, propellant charge, 4 tangential nozzles, ignition device, etc. Grain design, structure design and prediction of interior ballistic performance were described, and problem which need mainly considered in design were analyzed comprehensively. Finally, in order to research working performance of the SRM, measure pressure-time curve and its speed, static test and dynamic test were conducted respectively. And then calculated values and experimental data were compared and analyzed. The results indicate that the designed motor operates normally, and the stable performance of interior ballistic meet demands. And experimental results have the guidance meaning for the pre-research design of SRM.

  20. Characterizing the Experimental Procedure in Science Laboratories: A Preliminary Step towards Students Experimental Design

    Science.gov (United States)

    Girault, Isabelle; d'Ham, Cedric; Ney, Muriel; Sanchez, Eric; Wajeman, Claire

    2012-01-01

    Many studies have stressed students' lack of understanding of experiments in laboratories. Some researchers suggest that if students design all or parts of entire experiment, as part of an inquiry-based approach, it would overcome certain difficulties. It requires that a procedure be written for experimental design. The aim of this paper is to…

  1. Engineering design of a high-temperature superconductor current lead

    Science.gov (United States)

    Niemann, R. C.; Cha, Y. S.; Hull, J. R.; Daugherty, M. A.; Buckles, W. E.

    As part of the US Department of Energy's Superconductivity Pilot Center Program, Argonne National Laboratory and Superconductivity, Inc., are developing high-temperature superconductor (HTS) current leads suitable for application to superconducting magnetic energy storage systems. The principal objective of the development program is to design, construct, and evaluate the performance of HTS current leads suitable for near-term applications. Supporting objectives are to (1) develop performance criteria; (2) develop a detailed design; (3) analyze performance; (4) gain manufacturing experience in the areas of materials and components procurement, fabrication and assembly, quality assurance, and cost; (5) measure performance of critical components and the overall assembly; (6) identify design uncertainties and develop a program for their study; and (7) develop application-acceptance criteria.

  2. Tokamak experimental power reactor conceptual design. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    1976-08-01

    A conceptual design has been developed for a tokamak Experimental Power Reactor to operate at net electrical power conditions with a plant capacity factor of 50 percent for 10 years. The EPR operates in a pulsed mode at a frequency of approximately 1/min., with an approximate 75 percent duty cycle, is capable of producing approximately 72 MWe and requires 42 MWe. The annual tritium consumption is 16 kg. The EPR vacuum chamber is 6.25 m in major radius and 2.4 m in minor radius, is constructed of 2-cm thick stainless steel, and has 2-cm thick detachable, beryllium-coated coolant panels mounted on the interior. An 0.28 m stainless steel blanket and a shield ranging from 0.6 to 1.0 m surround the vacuum vessel. The coolant is H/sub 2/O. Sixteen niobium-titanium superconducting toroidal-field coils provide a field of 10 T at the coil and 4.47 T at the plasma. Superconducting ohmic-heating and equilibrium-field coils provide 135 V-s to drive the plasma current. Plasma heating is accomplished by 12 neutral beam-injectors, which provide 60 MW. The energy transfer and storage system consists of a central superconducting storage ring, a homopolar energy storage unit, and a variety of inductor-converters.

  3. Realizing life-scalable experimental pyroclastic density currents

    Science.gov (United States)

    Cronin, S. J.; Lube, G.; Breard, E.; Jones, J.; Valentine, G.; Freundt, A.; Hort, M. K.; Bursik, M. I.

    2013-12-01

    Pyroclastic Density Currents (PDCs) - the most deadly threat from volcanoes - are extremely hot, ground-hugging currents of rock fragments and gas that descend slopes at hundreds of kilometers per hour. These hostile flows are impossible to internally measure, thus volcanologists are persistently blocked in efforts to realistically forecast their internal mechanics and hazards. Attempts to fill this gap via laboratory-scale experiments continue to prove difficult, because they usually mismatch the dynamic and kinematic scaling of real-world flows by several orders of magnitude. In a multi-institutional effort, the first large-scale pyroclastic flow generator that can synthesize repeatable hot high-energy gas-particle mixture flows in safety has been commissioned in New Zealand. The final apparatus stands 15 m high, consisting of a tower/elevator system; an instrumented hopper that can hold >6000 kg (or 3.2 m3) of natural volcanic materials, which can be discharged at a range of controlled rates onto an instrumented, variably inclinable (6-25°) glass-sided chute for examining the vertical profiles of PDCs in motion. The use of rhyolitic pyroclastic material from the 1800 AD Taupo Eruption (with its natural grain-size, sorting and shape characteristics) and gas ensures natural coupling between the solids and fluid phases. PDC analogues with runout of >15 meters and flow depths of 1.5-6 meters are created by generating variably heated falling columns of natural volcanic particles (50-1300 kg/s), dispersed and aerated to controlled particle densities between 3 and 60 vol.% at the base of the elevated hopper. The descending columns rapidly generate high-velocity flows (up to 14 m/s) once impacting on the inclined channel, reproducing many features of natural flows, including segregation into dense and dilute regimes, progressive aggradational and en masse deposition of particles and the development of high internal gas-pore-pressures during flow. The PDC starting

  4. Useful experimental designs and rank order statistics in educational research

    Directory of Open Access Journals (Sweden)

    Zendler, Andreas

    2013-01-01

    Full Text Available Experimental educational research is of great impact because it illuminates cause-and-effect relationships by accumulating empirical evidence. The present article does not propose new methods but brings three useful experimental designs as well as appropriate statistical procedures (rank order statistics to the attention of the reader to conduct educational experiments, even with small samples. By means of their systematic use combined with the process-product paradigm of experimental educational research, the influence of essential variables (teacher, context, and process variables in schools, universities, and other educational institutions can be investigated. The statistical procedures described in this article guarantee that small samples (e.g. a school class can be successfully used, and that product variables (e.g. knowledge, comprehension, transfer are only required to meet the criteria of an ordinal scale. The experimental designs and statistical procedures are exemplified by hypothetical data and detailed calculations.

  5. Reliability of single sample experimental designs: comfortable effort level.

    Science.gov (United States)

    Brown, W S; Morris, R J; DeGroot, T; Murry, T

    1998-12-01

    This study was designed to ascertain the intrasubject variability across multiple recording sessions-most often disregarded in reporting group mean data or unavailable because of single sample experimental designs. Intrasubject variability was assessed within and across several experimental sessions from measures of speaking fundamental frequency, vocal intensity, and reading rate. Three age groups of men and women--young, middle-aged, and elderly--repeated the vowel /a/, read a standard passage, and spoke extemporaneously during each experimental session. Statistical analyses were performed to assess each speaker's variability from his or her own mean, and that which consistently varied for any one speaking sample type, both within or across days. Results indicated that intrasubject variability was minimal, with approximately 4% of the data exhibiting significant variation across experimental sessions.

  6. Analytical and experimental study of freeform object design and simultaneous manufacturing

    Science.gov (United States)

    Zhang, Weihan; Zhang, Wei; Wang, Xiaofang; Yan, Jingbin

    2003-04-01

    Applications of Virtual Reality (VR) technology in many fields have gained great success. In the product development field, VR is a good tool to provide interactive and friendly human-machine interface. Freeform Object Design and Simultaneous Manufacturing (FODSM) uses VR to establish an interactive design environment and enable simultaneous manufacturing. It aims at improving design efficiency, creativity, ease of use, and also aims at integrating design and manufacturing in order to obtain the designed object by the designer independently and simultaneously. For the current stage, key technologies to implement FODSM include the algorithm of swept volume calculation and the following Boolean operation, mechanism to provide natural and intuitive feedback. This paper uses an analytical and experimental method to implement the novel design and manufacturing technology. Key issues are analyzed and tested. Experimental details are demonstrated.

  7. Computer-Generated Experimental Designs for Irregular-Shaped Regions

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Nam K.; Piepel, Gregory F.

    2005-09-01

    This paper focuses on the construction of computer-generated designs on irregularly-shaped, constrained regions. Overviews of the Fedorov exchange algorithm (FEA) and other exchange algorithms for the construction of D-optimal designs are given. A faster implementation of the FEA is presented, which is referred to as fast-FEA (denoted FFEA). The FFEA was applied to construct D-optimal designs for several published examples with constrained experimental regions. Designs resulting from the FFEA are more D-efficient than published designs, and provide benchmarks for future comparisons of design construction algorithms. The construction of G-optimal designs for constrained regions is also discussed and illustrated with a published example.

  8. Current control loop design and analysis based on resonant regulators for microgrid applications

    DEFF Research Database (Denmark)

    Federico, de Bosio; Pastorelli, Michelle; de Sousa Ribeiro, Luiz Antonio

    2015-01-01

    Voltage and current control loops play an important role in the performance of microgrids employing power electronics voltage source inverters. Correct design of feedback loops is essential for the proper operation of these systems. This paper analyzes the influence of state feedback cross......-coupling in the design of resonant regulators for inner current loops in power converters operating in standalone microgrids. It is also demonstrated that the effect of state feedback cross-coupling degrades the performance of the control loops by increasing the steady-state error. Different resonant regulators...... structures are analyzed and compared, performing experimental tests to validate the results of the theoretical analysis....

  9. Experimental Design and Power Calculation for RNA-seq Experiments.

    Science.gov (United States)

    Wu, Zhijin; Wu, Hao

    2016-01-01

    Power calculation is a critical component of RNA-seq experimental design. The flexibility of RNA-seq experiment and the wide dynamic range of transcription it measures make it an attractive technology for whole transcriptome analysis. These features, in addition to the high dimensionality of RNA-seq data, bring complexity in experimental design, making an analytical power calculation no longer realistic. In this chapter we review the major factors that influence the statistical power of detecting differential expression, and give examples of power assessment using the R package PROPER.

  10. Optimal Experimental Design of Furan Shock Tube Kinetic Experiments

    KAUST Repository

    Kim, Daesang

    2015-01-07

    A Bayesian optimal experimental design methodology has been developed and applied to refine the rate coefficients of elementary reactions in Furan combustion. Furans are considered as potential renewable fuels. We focus on the Arrhenius rates of Furan + OH ↔ Furyl-2 + H2O and Furan ↔ OH Furyl-3 + H2O, and rely on the OH consumption rate as experimental observable. A polynomial chaos surrogate is first constructed using an adaptive pseudo-spectral projection algorithm. The PC surrogate is then exploited in conjunction with a fast estimation of the expected information gain in order to determine the optimal design in the space of initial temperatures and OH concentrations.

  11. Conceptual design of superconducting magnet systems for the Argonne Tokamak Experimental Power Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Wang, S.T.; Turner, L.R.; Mills, F.E.; DeMichele, D.W.; Smelser, P.; Kim, S.H.

    1976-01-01

    As an integral effort in the Argonne Tokamak Experimental Power Reactor Conceptual Design, the conceptual design of a 10-tesla, pure-tension superconducting toroidal-field (TF) coil system has been developed in sufficient detail to define a realistic design for the TF coil system that could be built based upon the current state of technology with minimum technological extrapolations. A conceptual design study on the superconducting ohmic-heating (OH) coils and the superconducting equilibrium-field (EF) coils were also completed. These conceptual designs are developed in sufficient detail with clear information on high current ac conductor design, cooling, venting provision, coil structural support and zero loss poloidal coil cryostat design. Also investigated is the EF penetration into the blanket and shield.

  12. Optimal Bayesian experimental design for contaminant transport parameter estimation

    CERN Document Server

    Tsilifis, Panagiotis; Hajali, Paris

    2015-01-01

    Experimental design is crucial for inference where limitations in the data collection procedure are present due to cost or other restrictions. Optimal experimental designs determine parameters that in some appropriate sense make the data the most informative possible. In a Bayesian setting this is translated to updating to the best possible posterior. Information theoretic arguments have led to the formation of the expected information gain as a design criterion. This can be evaluated mainly by Monte Carlo sampling and maximized by using stochastic approximation methods, both known for being computationally expensive tasks. We propose an alternative framework where a lower bound of the expected information gain is used as the design criterion. In addition to alleviating the computational burden, this also addresses issues concerning estimation bias. The problem of permeability inference in a large contaminated area is used to demonstrate the validity of our approach where we employ the massively parallel vers...

  13. Design of a Novel Current Balanced Voltage Controlled Delay Element

    Directory of Open Access Journals (Sweden)

    Pooja Saxena

    2014-04-01

    Full Text Available This paper presents a design of fast voltage controlled delay element based on modified version of low noise Current Balanced Logic (CBL. This delay element provides identical rising and falling edge delays controlled by the single control voltage. The post layout tunable delay range is from 140 ps to 800 ps over control voltage range of 0 to 2.1 V. An analysis for the delay element is also presented, which is in agreement with the simulated delays. A Delay Lock Loop (DLL is designed using this delay element to verify its performance.

  14. Applications of Chemiluminescence in the Teaching of Experimental Design

    Science.gov (United States)

    Krawczyk, Tomasz; Slupska, Roksana; Baj, Stefan

    2015-01-01

    This work describes a single-session laboratory experiment devoted to teaching the principles of factorial experimental design. Students undertook the rational optimization of a luminol oxidation reaction, using a two-level experiment that aimed to create a long-lasting bright emission. During the session students used only simple glassware and…

  15. Single-Subject Experimental Design for Evidence-Based Practice

    Science.gov (United States)

    Byiers, Breanne J.; Reichle, Joe; Symons, Frank J.

    2012-01-01

    Purpose: Single-subject experimental designs (SSEDs) represent an important tool in the development and implementation of evidence-based practice in communication sciences and disorders. The purpose of this article is to review the strategies and tactics of SSEDs and their application in speech-language pathology research. Method: The authors…

  16. Experimental design of natural and accellerated bone and wood ageing

    DEFF Research Database (Denmark)

    Facorellis, Y.; Pournou, A.; Richter, Jane;

    2015-01-01

    This paper presents the experimental design for natural and accelerated ageing of bone and wood samples found in museum conditions that was conceived as part of the INVENVORG (Thales Research Funding Program – NRSF) investigating the effects of the environmental factors on natural organic materials....

  17. Using Propensity Score Methods to Approximate Factorial Experimental Designs

    Science.gov (United States)

    Dong, Nianbo

    2011-01-01

    The purpose of this study is through Monte Carlo simulation to compare several propensity score methods in approximating factorial experimental design and identify best approaches in reducing bias and mean square error of parameter estimates of the main and interaction effects of two factors. Previous studies focused more on unbiased estimates of…

  18. Model selection in systems biology depends on experimental design.

    Science.gov (United States)

    Silk, Daniel; Kirk, Paul D W; Barnes, Chris P; Toni, Tina; Stumpf, Michael P H

    2014-06-01

    Experimental design attempts to maximise the information available for modelling tasks. An optimal experiment allows the inferred models or parameters to be chosen with the highest expected degree of confidence. If the true system is faithfully reproduced by one of the models, the merit of this approach is clear - we simply wish to identify it and the true parameters with the most certainty. However, in the more realistic situation where all models are incorrect or incomplete, the interpretation of model selection outcomes and the role of experimental design needs to be examined more carefully. Using a novel experimental design and model selection framework for stochastic state-space models, we perform high-throughput in-silico analyses on families of gene regulatory cascade models, to show that the selected model can depend on the experiment performed. We observe that experimental design thus makes confidence a criterion for model choice, but that this does not necessarily correlate with a model's predictive power or correctness. Finally, in the special case of linear ordinary differential equation (ODE) models, we explore how wrong a model has to be before it influences the conclusions of a model selection analysis.

  19. Applications of Chemiluminescence in the Teaching of Experimental Design

    Science.gov (United States)

    Krawczyk, Tomasz; Slupska, Roksana; Baj, Stefan

    2015-01-01

    This work describes a single-session laboratory experiment devoted to teaching the principles of factorial experimental design. Students undertook the rational optimization of a luminol oxidation reaction, using a two-level experiment that aimed to create a long-lasting bright emission. During the session students used only simple glassware and…

  20. Statistiscal Experimental Design for Quantitative Atomic Resolution Transmission Electron Microscopy

    NARCIS (Netherlands)

    Van Aert, S.

    2003-01-01

    Statistical experimental design is applied to set up quantitative atomic resolution transmission electron microscopy experiments. In such experiments, observations of the atomic structure of the object under study are always subject to spontaneous fluctuations. As a result of these fluctuations, the

  1. Using experimental designs to understand the development of peer relations

    NARCIS (Netherlands)

    Orobio De Castro, Bram; Thomaes, Sander; Reijntjes, Albert

    2015-01-01

    In the past decades, tremendous advances have been made in our understanding of peer relations. A description is emerging of how peer relations develop. Surprisingly, though, we know less about why peer relations develop as they do. Experimental designs provide opportunities to learn about causal pr

  2. Taguchi method of experimental design in materials education

    Science.gov (United States)

    Weiser, Martin W.

    1993-01-01

    Some of the advantages and disadvantages of the Taguchi Method of experimental design as applied to Materials Science will be discussed. This is a fractional factorial method that employs the minimum number of experimental trials for the information obtained. The analysis is also very simple to use and teach, which is quite advantageous in the classroom. In addition, the Taguchi loss function can be easily incorporated to emphasize that improvements in reproducibility are often at least as important as optimization of the response. The disadvantages of the Taguchi Method include the fact that factor interactions are normally not accounted for, there are zero degrees of freedom if all of the possible factors are used, and randomization is normally not used to prevent environmental biasing. In spite of these disadvantages it is felt that the Taguchi Method is extremely useful for both teaching experimental design and as a research tool, as will be shown with a number of brief examples.

  3. Optimal Experimental Design for Large-Scale Bayesian Inverse Problems

    KAUST Repository

    Ghattas, Omar

    2014-01-06

    We develop a Bayesian framework for the optimal experimental design of the shock tube experiments which are being carried out at the KAUST Clean Combustion Research Center. The unknown parameters are the pre-exponential parameters and the activation energies in the reaction rate expressions. The control parameters are the initial mixture composition and the temperature. The approach is based on first building a polynomial based surrogate model for the observables relevant to the shock tube experiments. Based on these surrogates, a novel MAP based approach is used to estimate the expected information gain in the proposed experiments, and to select the best experimental set-ups yielding the optimal expected information gains. The validity of the approach is tested using synthetic data generated by sampling the PC surrogate. We finally outline a methodology for validation using actual laboratory experiments, and extending experimental design methodology to the cases where the control parameters are noisy.

  4. Electrostatic discharge current linear approach and circuit design method

    Energy Technology Data Exchange (ETDEWEB)

    Katsivelis, P. K.; Fotis, G. P.; Gonos, I. F.; Koussiouris, T. G.; Stathopulos, I. A. [School of Electrical and Computer Engineering, National Technical University of Athens, 9 Iroon Polytechniou Str., Zographou 157 80, Athens (Greece)

    2010-11-15

    The electrostatic discharge (ESD) phenomenon is a great threat to all electronic devices and ICs. An electric charge passing rapidly from a charged body to another can seriously harm the last one. However, there is a lack in a linear mathematical approach which will make it possible to design a circuit capable of producing such a sophisticated current waveform. The commonly accepted electrostatic discharge current waveform is the one set by the IEC 61000-4-2. However, the over-simplified circuit included in the same standard is incapable of producing such a waveform. Treating the electrostatic discharge current waveform of the IEC 61000-4-2 as reference, an approximation method, based on Prony's method, is developed and applied in order to obtain a linear system's response. Considering a known input, a method to design a circuit, able to generate this ESD current waveform in presented. The circuit synthesis assumes ideal active elements. A simulation is carried out using the PSpice software. (authors)

  5. Design and Experimental Research on a New Pipe Rupture Valve

    Institute of Scientific and Technical Information of China (English)

    HU Guo-liang; XU Bing; YANG Hua-yong; ZHANG Yi-ding

    2006-01-01

    A new pipe rupture valve for hydraulic elevator is designed.Mathematical models established for the hydraulic elevator system are used in numefical simulations on the Simulink environment of Matlab kits.The effects of different viscous damping diameters.inlet pressures of pipe rupture valve.and elevator loads on the hydraulic elevator system's dynamic performance are analyzed.Expefimenml research is also carried out using a hydraulic elevator experiment rig.The numerical simulations accord with experimental results in general.Dynamic performance indexes are assessed by the EN812 standard.The results show that the newly designed pipe rupture valve meets the designing requirement for hydraulic elevators.

  6. Application of quality by design in the current drug development

    Directory of Open Access Journals (Sweden)

    Lan Zhang

    2017-01-01

    Full Text Available Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design (QbD in the field of pharmacy, which is based on the thorough understanding of how materials and process parameters affect the quality profile of final products. The application of QbD in drug formulation and process design is based on a good understanding of the sources of variability and the manufacture process. In this paper, the basic knowledge of QbD, the elements of QbD, steps and tools for QbD implementation in pharmaceutics field, including risk assessment, design of experiment, and process analytical technology (PAT, are introduced briefly. Moreover, the concrete applications of QbD in various pharmaceutical related unit operations are summarized and presented.

  7. Computational design and experimental validation of new thermal barrier systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin [Louisiana State Univ., Baton Rouge, LA (United States)

    2015-03-31

    The focus of this project is on the development of a reliable and efficient ab initio based computational high temperature material design method which can be used to assist the Thermal Barrier Coating (TBC) bond-coat and top-coat design. Experimental evaluations on the new TBCs are conducted to confirm the new TBCs’ properties. Southern University is the subcontractor on this project with a focus on the computational simulation method development. We have performed ab initio density functional theory (DFT) method and molecular dynamics simulation on screening the top coats and bond coats for gas turbine thermal barrier coating design and validation applications. For experimental validations, our focus is on the hot corrosion performance of different TBC systems. For example, for one of the top coatings studied, we examined the thermal stability of TaZr2.75O8 and confirmed it’s hot corrosion performance.

  8. Convergence in parameters and predictions using computational experimental design.

    Science.gov (United States)

    Hagen, David R; White, Jacob K; Tidor, Bruce

    2013-08-06

    Typically, biological models fitted to experimental data suffer from significant parameter uncertainty, which can lead to inaccurate or uncertain predictions. One school of thought holds that accurate estimation of the true parameters of a biological system is inherently problematic. Recent work, however, suggests that optimal experimental design techniques can select sets of experiments whose members probe complementary aspects of a biochemical network that together can account for its full behaviour. Here, we implemented an experimental design approach for selecting sets of experiments that constrain parameter uncertainty. We demonstrated with a model of the epidermal growth factor-nerve growth factor pathway that, after synthetically performing a handful of optimal experiments, the uncertainty in all 48 parameters converged below 10 per cent. Furthermore, the fitted parameters converged to their true values with a small error consistent with the residual uncertainty. When untested experimental conditions were simulated with the fitted models, the predicted species concentrations converged to their true values with errors that were consistent with the residual uncertainty. This paper suggests that accurate parameter estimation is achievable with complementary experiments specifically designed for the task, and that the resulting parametrized models are capable of accurate predictions.

  9. Lab-Scale Fiber Spinning Experimental Design Cost Comparison

    Directory of Open Access Journals (Sweden)

    Jeffrey C. Moreland

    2010-03-01

    Full Text Available Many statistical experimental designs are too costlyor require too much raw material to be feasible forlab-scale fiber spinning experiments. In this study afour-factor response surface design is presented tostudy the fiber spinning process in detail at the labscale. The time, cost, and amount of raw materialrequired to execute the proposed design are comparedto the typical completely randomized 24 factorialdesign used in fiber spinning experiments and also toa standard four-factor response surface design.Sample fiber data as well as analysis from a typicalstatistical software package is provided to furtherdemonstrate the differences between each design. Bydesignating some treatment factors in the design ashard-to-change, split-plotting is used to reduce thetime, cost, and amount of raw material required tocomplete the experiment. The proposed split-plotdesign is faster and less expensive than a typicalfactorial design and has the advantage of fitting amore complex second-order model to the system.When compared to a standard response surfacedesign, the proposed split-plot design provides thesame second-order modeling capabilities but reducesthe cost of the experiment by 53%, the total time by36%, and the amount of polymer required by 24%.Thus, a split-plot response surface design based onhard-to-change factors is recommended in lab-scalespinning.

  10. Experimental design for parameter estimation of gene regulatory networks.

    Directory of Open Access Journals (Sweden)

    Bernhard Steiert

    Full Text Available Systems biology aims for building quantitative models to address unresolved issues in molecular biology. In order to describe the behavior of biological cells adequately, gene regulatory networks (GRNs are intensively investigated. As the validity of models built for GRNs depends crucially on the kinetic rates, various methods have been developed to estimate these parameters from experimental data. For this purpose, it is favorable to choose the experimental conditions yielding maximal information. However, existing experimental design principles often rely on unfulfilled mathematical assumptions or become computationally demanding with growing model complexity. To solve this problem, we combined advanced methods for parameter and uncertainty estimation with experimental design considerations. As a showcase, we optimized three simulated GRNs in one of the challenges from the Dialogue for Reverse Engineering Assessment and Methods (DREAM. This article presents our approach, which was awarded the best performing procedure at the DREAM6 Estimation of Model Parameters challenge. For fast and reliable parameter estimation, local deterministic optimization of the likelihood was applied. We analyzed identifiability and precision of the estimates by calculating the profile likelihood. Furthermore, the profiles provided a way to uncover a selection of most informative experiments, from which the optimal one was chosen using additional criteria at every step of the design process. In conclusion, we provide a strategy for optimal experimental design and show its successful application on three highly nonlinear dynamic models. Although presented in the context of the GRNs to be inferred for the DREAM6 challenge, the approach is generic and applicable to most types of quantitative models in systems biology and other disciplines.

  11. Design and experimental results for the S809 airfoil

    Energy Technology Data Exchange (ETDEWEB)

    Somers, D M [Airfoils, Inc., State College, PA (United States)

    1997-01-01

    A 21-percent-thick, laminar-flow airfoil, the S809, for horizontal-axis wind-turbine applications, has been designed and analyzed theoretically and verified experimentally in the low-turbulence wind tunnel of the Delft University of Technology Low Speed Laboratory, The Netherlands. The two primary objectives of restrained maximum lift, insensitive to roughness, and low profile drag have been achieved. The airfoil also exhibits a docile stall. Comparisons of the theoretical and experimental results show good agreement. Comparisons with other airfoils illustrate the restrained maximum lift coefficient as well as the lower profile-drag coefficients, thus confirming the achievement of the primary objectives.

  12. Experimental modeling of high-voltage corona discharge using design of experiments

    Institute of Scientific and Technical Information of China (English)

    Rezzouga M; Tilmatine A; Gouri R; Medics K; Dascalescu L

    2007-01-01

    Many studies,both experimental and numerical,were devoted to the electric current of corona discharge and some mathematical models were proposed to express it.As it depends on several parameters,it is difficult to find a theoretical or an experimental formula,which considers all the factors.So we opted for the methodology of experimental designs,also called Tagushi's methodology,which represents a powerful tool generally employed when the process has many factors to consider.The objective of this paper is to model current using this experimental methodology.The factors considered were geometrical factors (interelectrode interval,surface of the grounded plane electrode,curvature radius of the point electrode),climatic factors (temperature and relative humidity),and applied high voltage.Results of experiments made it possible to obtain mathematical models and to analyse the interactions between all factors.

  13. Currents, HF Radio-derived, Monterey Bay, 1 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  14. Currents, HF Radio-derived, SF Bay, 1 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  15. Currents, HF Radio-derived, SF Bay Outlet, 1 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  16. Currents, HF Radio-derived, SF Bay Outlet, 1 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  17. Currents, HF Radio-derived, Bodega Bay, 1 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  18. Currents, HF Radio-derived, Bodega Bay, 1 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  19. Currents, HF Radio-derived, Ano Nuevo, 1 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  20. Currents, HF Radio-derived, Ano Nuevo, 1 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 1 hour average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN EXPERIMENTAL...

  1. Design of Current steering DAC using 250nm CMOS Technology

    Directory of Open Access Journals (Sweden)

    Vineet Tiwari

    2012-06-01

    Full Text Available To build a digital to analog converter, that only receives digital signal that can only receives digital signal and produces only analog signal. A converter in which digital input signals are changed to essentially proportional analog signals. Abbreviated DAC a device for converting information in the forms of combination of discrete(usually binary states or signal to information in the form of combinations of discrete(usually binary states or signal to information in the form of value or magnitude of some characteristics of signal, in relation to standard or reference signal. Digital-toanalog (D/A converters (sometimes called DACs are used to present the results of digital computation, storage, or transmission, typically for graphical display or for the control of devices that operate with continuously varying quantities. D/A converter circuits are also used in the design of analog-to-digital converters that employ feedback techniques, such as successive-approximation and counter-comparator types. In such applications, the D/A converter may not necessarily appear as a separately identifiable entity. The fundamental circuit of most D/A converters involves a voltage or current reference; a resistive “ladder network” that derives weighted currents or voltages, usually as discrete fractions of the reference; and a set of switches, operated by the digital input, that determines which currents or voltages will be summed to constitute the output. The output of the D/A converter is proportional to the product of the digital input value and the reference. In many applications, the reference is fixed, and the output bears a fixed proportion to the digital input. In other applications, the reference, as well as the digital input, can vary; a D/A converter that is used in these applications is thus called a multiplying D/A converter. It is principally used for imparting a digitally controlled scale factor, or “gain,” to an analog input signal

  2. Current trends in health facility planning, design, and construction.

    Science.gov (United States)

    Beale, Craig; Kittredge, Frank D

    2014-01-01

    It is critical now more than ever for today's healthcare facilities to serve as more than just a backdrop to the care provided--they can, and should, be an integral part of that care. In addition to promoting efficacy, delighting the senses, and placing patients and families at ease, facilities need to be high-performing, sustainable, and healthy environments. Creating today's healthcare facilities requires breaking through barriers in unexpected ways, and it often requires looking outside the healthcare profession for guidance. In this article, we explore current trends in health facility planning, design, and construction. Our focus is on the buildings that serve as venues for the provision of healthcare services across the full continuum, from prevention to critical care. In particular, we discuss four current broad trends and conclude with thoughts on future developments.

  3. Superconducting fault-current limiter and inductor design

    Science.gov (United States)

    Rogers, J. D.; Boenig, H. J.; Chowdhuri, P.; Schermer, R. I.; Wollan, J. J.; Weldon, D. M.

    1982-11-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components, superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator, included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  4. Super conducting fault current limiter and inductor design

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.; Boenig, H.; Chowdhuri, P.; Schermer, R.; Weldon, D.; Wollan, J.

    1983-05-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components--superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator--included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  5. Superconducting fault-current limiter and inductor design

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.D.; Boenig, H.J.; Chowdhuri, P.; Schermer, R.I.; Wollan, J.J.; Weldon, D.M.

    1982-01-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components - superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator - included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  6. Experimental design unified concepts, practical applications, and computer implementation

    CERN Document Server

    Bowerman, Bruce L

    2014-01-01

    This book is a concise and innovative book that gives a complete presentation of the design and analysis of experiments in approximately one half the space of competing books. With only the modest prerequisite of a basic (non-calculus) statistics course, this text is appropriate for the widest possible audience. Two procedures are generally used to analyze experimental design data-analysis of variance (ANOVA) and regression analysis. Because ANOVA is more intuitive, this book devotes most of its first three chapters to showing how to use ANOVA to analyze balanced (equal sample size) experiment

  7. Optimal active vibration absorber - Design and experimental results

    Science.gov (United States)

    Lee-Glauser, Gina; Juang, Jer-Nan; Sulla, Jeffrey L.

    1993-01-01

    An optimal active vibration absorber can provide guaranteed closed-loop stability and control for large flexible space structures with collocated sensors/actuators. The active vibration absorber is a second-order dynamic system which is designed to suppress any unwanted structural vibration. This can be designed with minimum knowledge of the controlled system. Two methods for optimizing the active vibration absorber parameters are illustrated: minimum resonant amplitude and frequency matched active controllers. The Controls-Structures Interaction Phase-1 Evolutionary Model at NASA LaRC is used to demonstrate the effectiveness of the active vibration absorber for vibration suppression. Performance is compared numerically and experimentally using acceleration feedback.

  8. Optimal active vibration absorber: Design and experimental results

    Science.gov (United States)

    Lee-Glauser, Gina; Juang, Jer-Nan; Sulla, Jeffrey L.

    1992-01-01

    An optimal active vibration absorber can provide guaranteed closed-loop stability and control for large flexible space structures with collocated sensors/actuators. The active vibration absorber is a second-order dynamic system which is designed to suppress any unwanted structural vibration. This can be designed with minimum knowledge of the controlled system. Two methods for optimizing the active vibration absorber parameters are illustrated: minimum resonant amplitude and frequency matched active controllers. The Controls-Structures Interaction Phase-1 Evolutionary Model at NASA LaRC is used to demonstrate the effectiveness of the active vibration absorber for vibration suppression. Performance is compared numerically and experimentally using acceleration feedback.

  9. TIBER: Tokamak Ignition/Burn Experimental Research. Final design report

    Energy Technology Data Exchange (ETDEWEB)

    Henning, C.D.; Logan, B.G.; Barr, W.L.; Bulmer, R.H.; Doggett, J.N.; Johnson, B.M.; Lee, J.D.; Hoard, R.W.; Miller, J.R.; Slack, D.S.

    1985-11-01

    The Tokamak Ignition/Burn Experimental Research (TIBER) device is the smallest superconductivity tokamak designed to date. In the design plasma shaping is used to achieve a high plasma beta. Neutron shielding is minimized to achieve the desired small device size, but the superconducting magnets must be shielded sufficiently to reduce the neutron heat load and the gamma-ray dose to various components of the device. Specifications of the plasma-shaping coil, the shielding, coaling, requirements, and heating modes are given. 61 refs., 92 figs., 30 tabs. (WRF)

  10. Fast Bayesian optimal experimental design and its applications

    KAUST Repository

    Long, Quan

    2015-01-07

    We summarize our Laplace method and multilevel method of accelerating the computation of the expected information gain in a Bayesian Optimal Experimental Design (OED). Laplace method is a widely-used method to approximate an integration in statistics. We analyze this method in the context of optimal Bayesian experimental design and extend this method from the classical scenario, where a single dominant mode of the parameters can be completely-determined by the experiment, to the scenarios where a non-informative parametric manifold exists. We show that by carrying out this approximation the estimation of the expected Kullback-Leibler divergence can be significantly accelerated. While Laplace method requires a concentration of measure, multi-level Monte Carlo method can be used to tackle the problem when there is a lack of measure concentration. We show some initial results on this approach. The developed methodologies have been applied to various sensor deployment problems, e.g., impedance tomography and seismic source inversion.

  11. Contract design and insurance fraud: An experimental investigation

    OpenAIRE

    Lammers, Frauke; Schiller, Jörg

    2010-01-01

    This paper investigates the impact of insurance contract design on the behavior of filing fraudulent claims in an experimental setup. We test how fraud behavior varies for insurance contracts with full coverage, a straight deductible or variable premiums (bonus-malus contract). In our experiment, filing fraudulent claims is a dominant strategy for selfish participants, with no psychological costs of committing fraud. While some people always commit fraud, a substantial share of people only oc...

  12. Experimental framework for autonomous fast ships's control design

    OpenAIRE

    Recas Piorno, Joaquín; Esteban San Román, Segundo; Girón Sierra, José María; Cruz García, Jesús Manuel de la

    2005-01-01

    The research on seakeeping control of fast ships requires difficult experiments for modeling and control design. To alleviate the ship motion certain active appendages are added, such moving flaps, T-foil and fins. The motion of appendages must be optimized to counteract each encountered wave. During our first research steps, a scaled down ship, with scaled appendages, has been used in a towing tank facility. The scaled ship is towed at fixed speeds of experimental interest, for instance at t...

  13. Gradient-based stochastic optimization methods in Bayesian experimental design

    OpenAIRE

    2012-01-01

    Optimal experimental design (OED) seeks experiments expected to yield the most useful data for some purpose. In practical circumstances where experiments are time-consuming or resource-intensive, OED can yield enormous savings. We pursue OED for nonlinear systems from a Bayesian perspective, with the goal of choosing experiments that are optimal for parameter inference. Our objective in this context is the expected information gain in model parameters, which in general can only be estimated u...

  14. Parameter Estimation and Experimental Design in Groundwater Modeling

    Institute of Scientific and Technical Information of China (English)

    SUN Ne-zheng

    2004-01-01

    This paper reviews the latest developments on parameter estimation and experimental design in the field of groundwater modeling. Special considerations are given when the structure of the identified parameter is complex and unknown. A new methodology for constructing useful groundwater models is described, which is based on the quantitative relationships among the complexity of model structure, the identifiability of parameter, the sufficiency of data, and the reliability of model application.

  15. Design of a Programmable Gain, Temperature Compensated Current-Input Current-Output CMOS Logarithmic Amplifier.

    Science.gov (United States)

    Ming Gu; Chakrabartty, Shantanu

    2014-06-01

    This paper presents the design of a programmable gain, temperature compensated, current-mode CMOS logarithmic amplifier that can be used for biomedical signal processing. Unlike conventional logarithmic amplifiers that use a transimpedance technique to generate a voltage signal as a logarithmic function of the input current, the proposed approach directly produces a current output as a logarithmic function of the input current. Also, unlike a conventional transimpedance amplifier the gain of the proposed logarithmic amplifier can be programmed using floating-gate trimming circuits. The synthesis of the proposed circuit is based on the Hart's extended translinear principle which involves embedding a floating-voltage source and a linear resistive element within a translinear loop. Temperature compensation is then achieved using a translinear-based resistive cancelation technique. Measured results from prototypes fabricated in a 0.5 μm CMOS process show that the amplifier has an input dynamic range of 120 dB and a temperature sensitivity of 230 ppm/°C (27 °C- 57°C), while consuming less than 100 nW of power.

  16. Current Parental Depression and Offspring Perceived Self-Competence: A Quasi-Experimental Examination

    Science.gov (United States)

    Class, Quetzal A.; D’Onofrio, Brian M.; Singh, Amber L.; Ganiban, Jody M.; Spotts, E. L.; Lichtenstein, Paul; Reiss, David; Neiderhiser, Jenae M.

    2013-01-01

    A genetically-informed, quasi-experimental design was used to examine the genetic and environmental processes underlying associations between current parental depressive symptoms and offspring perceived self-competence. Participants, drawn from a population-based Swedish sample, were 852 twin pairs and their male (52%) and female offspring aged 15.7 ± 2.4 years. Parental depressive symptoms were measured using the Center for Epidemiological Studies Depression scale. Offspring perceived self-competence was measured using a modified Harter Perceived Competence Scale. Cousin comparisons and Children of Twins (CoT) designs suggested that associations between maternal depressive symptoms and offspring perceived self-competence were due to shared genetic/environmental liability. The mechanism responsible for father-offspring associations, however, was independent of genetic factors and of extended-family environmental factors, supporting a causal inference. Thus, mothers and fathers may impact offspring perceived self-competence via different mechanisms and unmeasured genetic and environmental selection factors must be considered when studying the intergenerational transmission of cognitive vulnerabilities for depression. PMID:22692226

  17. Inner Current Loop Analysis and Design Based on Resonant Regulators for Isolated Microgrids

    DEFF Research Database (Denmark)

    Federico, de Bosio; de Sousa Ribeiro, Luiz Antonio; Soares Lima, Marcel

    2015-01-01

    coupling in the design of proportional resonant controllers for these inner loops in voltage source inverters operating in islanded microgrids. It is also shown that the state feedback coupling has an important effect in the performance of the control loops by increasing the steady-state error......Inner current and voltage loops are fundamental in achieving good performance of microgrids based on power electronics voltage source inverters. The analysis and design of these loops are essential for the adequate operation of these systems. This paper investigates the effect of state feedback....... A comparison between different types of proportional+resonant controllers is done. Experimental results verify the theoretical assumptions done....

  18. Single Phase Current-Source Active Rectifier for Traction: Control System Design and Practical Problems

    Directory of Open Access Journals (Sweden)

    Jan Michalik

    2006-01-01

    Full Text Available This research has been motivated by industrial demand for single phase current-source active rectifier dedicated for reconstruction of older types of dc machine locomotives. This paper presents converters control structure design and simulations. The proposed converter control is based on the mathematical model and due to possible interaction with railway signaling and required low switching frequency employs synchronous PWM. The simulation results are verified by experimental tests performed on designed laboratory prototype of power of 7kVA

  19. Incorporating experimental design and error into coalescent/mutation models of population history.

    Science.gov (United States)

    Knudsen, Bjarne; Miyamoto, Michael M

    2007-08-01

    Coalescent theory provides a powerful framework for estimating the evolutionary, demographic, and genetic parameters of a population from a small sample of individuals. Current coalescent models have largely focused on population genetic factors (e.g., mutation, population growth, and migration) rather than on the effects of experimental design and error. This study develops a new coalescent/mutation model that accounts for unobserved polymorphisms due to missing data, sequence errors, and multiple reads for diploid individuals. The importance of accommodating these effects of experimental design and error is illustrated with evolutionary simulations and a real data set from a population of the California sea hare. In particular, a failure to account for sequence errors can lead to overestimated mutation rates, inflated coalescent times, and inappropriate conclusions about the population. This current model can now serve as a starting point for the development of newer models with additional experimental and population genetic factors. It is currently implemented as a maximum-likelihood method, but this model may also serve as the basis for the development of Bayesian approaches that incorporate experimental design and error.

  20. Bayesian Optimal Experimental Design Using Multilevel Monte Carlo

    KAUST Repository

    Issaid, Chaouki Ben

    2015-01-07

    Experimental design is very important since experiments are often resource-exhaustive and time-consuming. We carry out experimental design in the Bayesian framework. To measure the amount of information, which can be extracted from the data in an experiment, we use the expected information gain as the utility function, which specifically is the expected logarithmic ratio between the posterior and prior distributions. Optimizing this utility function enables us to design experiments that yield the most informative data for our purpose. One of the major difficulties in evaluating the expected information gain is that the integral is nested and can be high dimensional. We propose using Multilevel Monte Carlo techniques to accelerate the computation of the nested high dimensional integral. The advantages are twofold. First, the Multilevel Monte Carlo can significantly reduce the cost of the nested integral for a given tolerance, by using an optimal sample distribution among different sample averages of the inner integrals. Second, the Multilevel Monte Carlo method imposes less assumptions, such as the concentration of measures, required by Laplace method. We test our Multilevel Monte Carlo technique using a numerical example on the design of sensor deployment for a Darcy flow problem governed by one dimensional Laplace equation. We also compare the performance of the Multilevel Monte Carlo, Laplace approximation and direct double loop Monte Carlo.

  1. Design of Bi-Directional Hydrofoils for Tidal Current Turbines

    Science.gov (United States)

    Nedyalkov, Ivaylo; Wosnik, Martin

    2015-11-01

    Tidal Current Turbines operate in flows which reverse direction. Bi-directional hydrofoils have rotational symmetry and allow such turbines to operate without the need for pitch or yaw control, decreasing the initial and maintenance costs. A numerical test-bed was developed to automate the simulations of hydrofoils in OpenFOAM and was utilized to simulate the flow over eleven classes of hydrofoils comprising a total of 700 foil shapes at different angles of attack. For promising candidate foil shapes physical models of 75 mm chord and 150 mm span were fabricated and tested in the University of New Hampshire High-Speed Cavitation Tunnel (HiCaT). The experimental results were compared to the simulations for model validation. The numerical test-bed successfully generated simulations for a wide range of foil shapes, although, as expected, the k - ω - SST turbulence model employed here was not adequate for some of the foils and for large angles of attack at which separation occurred. An optimization algorithm is currently being coupled with the numerical test-bed and additional turbulence models will be implemented in the future.

  2. Theoretical and experimental performance analysis for cold trap design

    Energy Technology Data Exchange (ETDEWEB)

    Hemanath, M.G., E-mail: hemanath@igcar.gov.i [Fast Reactor Technology Group, Indira Gandhi Center for Atomic Research, Kalpakkam (India); Meikandamurthy, C.; Kumar, A. Ashok; Chandramouli, S.; Rajan, K.K.; Rajan, M.; Vaidyanathan, G.; Padmakumar, G.; Kalyanasundaram, P.; Raj, Baldev [Fast Reactor Technology Group, Indira Gandhi Center for Atomic Research, Kalpakkam (India)

    2010-10-15

    Cold trap is a purification unit used in sodium system of FBR's for maintaining the oxygen/hydrogen level in sodium within acceptable limits. It works on the principle of crystallization and precipitation of oxides/hydrides of sodium in a wire mesh, when the temperature of sodium is reduced below the saturation temperature. The cold traps presently used have lower effectiveness and get plugged prematurely. The plugged cold traps are cleaned and then put back into service. Frequent cleaning of cold trap results in the long down time of the sodium system. New design of cold trap has been conceived to overcome the above problems. The mathematical modeling for the new design was carried out and validated with experimentally tested results for its effectiveness. This paper shares the experience gained on the new design of cold trap for FBR's.

  3. Design and experimental study of a novel giant magnetostrictive actuator

    Science.gov (United States)

    Xue, Guangming; Zhang, Peilin; He, Zhongbo; Li, Dongwei; Huang, Yingjie; Xie, Wenqiang

    2016-12-01

    Giant magnetostrictive actuator has been widely used in precise driving occasions for its excellent performance. However, in driving a switching valve, especially the ball-valve in an electronic controlled injector, the actuator can't exhibit its good performance for limits in output displacement and responding speed. A novel giant magnetostrictive actuator, which can reach its maximum displacement for being exerted with no bias magnetic field, is designed in this paper. Simultaneously, elongating of the giant magetostrictive material is converted to shortening of the actuator's axial dimension with the help of an output rod in "T" type. Furthermore, to save responding time, the driving voltage with high opening voltage while low holding voltage is designed. Responding time and output displacement are studied experimentally with the help of a measuring system. From measured results, designed driving voltage can improve the responding speed of actuator displacement quite effectively. And, giant magnetostrictive actuator can output various steady-state displacements to reach more driving effects.

  4. Flux quantum tunneling effect and its influence on the experimental critical current density

    Institute of Scientific and Technical Information of China (English)

    闻海虎; 赵忠贤; GriessenR.

    1995-01-01

    By using magnetic sweeping method, the temperature and magnetic field dependencies of the experimental current density and the normalized relaxation rate have been obtained. The true critical current density corresponding to the zero activation energy has been carried out based on the collective-pinning and the thermally-activated flux motion models, and therefore the influences of the quantum tunneling effect and the thermal activation effect on the experimental critical current density are distinguished. It is found that, with temperature lower than 10 K, the relaxation rate will not drop to zero when T approaches zero K because of the occurrence of the flux quantum tunneling. This additional flux motion further reduces the experimental critical current density j making it saturated with lowering temperature.

  5. Experimental study of yttrium barium copper oxide superconducting tape’s critical current under twisting moment

    Indian Academy of Sciences (India)

    Ziauddin Khan; Ananya Kundu; Subrata Pradhan

    2013-10-01

    Critical current (c) characteristics of 2G YBCO superconducting tape under the influence of twisting moment was experimentally investigated at varying current ramp rates in the self-field. Under a uniform twist, the degradation in the current-carrying capacity of YBCO tape up to 30% was observed at 77 K. The degradation is largely attributed to the shear stress and torsional shear strain resulting from the twisting. The superconductor to resistive transition index, , is also found to behave in an identical manner with increase in the twisting. Finite element analysis (FEA) of the tape in the experimental configuration with twisting moment being applied on to it has been carried out in COMSOL. The torsional strain calculated analytically as per the experimental configuration matches closely with that of FEA results, which shows that the critical current degradation is a function of strain.

  6. Entropy-Based Search Algorithm for Experimental Design

    Science.gov (United States)

    Malakar, N. K.; Knuth, K. H.

    2011-03-01

    The scientific method relies on the iterated processes of inference and inquiry. The inference phase consists of selecting the most probable models based on the available data; whereas the inquiry phase consists of using what is known about the models to select the most relevant experiment. Optimizing inquiry involves searching the parameterized space of experiments to select the experiment that promises, on average, to be maximally informative. In the case where it is important to learn about each of the model parameters, the relevance of an experiment is quantified by Shannon entropy of the distribution of experimental outcomes predicted by a probable set of models. If the set of potential experiments is described by many parameters, we must search this high-dimensional entropy space. Brute force search methods will be slow and computationally expensive. We present an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment for efficient experimental design. This algorithm is inspired by Skilling's nested sampling algorithm used in inference and borrows the concept of a rising threshold while a set of experiment samples are maintained. We demonstrate that this algorithm not only selects highly relevant experiments, but also is more efficient than brute force search. Such entropic search techniques promise to greatly benefit autonomous experimental design.

  7. Design of a CMOS temperature sensor with current output

    NARCIS (Netherlands)

    Kolling, A.; Kölling, Arjan; Bak, Frans; Bergveld, Piet; Seevinck, E.; Seevinck, Evert

    1990-01-01

    In this paper a CMOS temperature-to-current converter is presented of which the output current is the difference between a PTC current and an NTC current. The PTC current is derived from a PTAT cell, while the NTC current is derived from a threshold voltage reference source. It is shown that this

  8. Entropy-Based Search Algorithm for Experimental Design

    CERN Document Server

    Malakar, N K

    2010-01-01

    The scientific method relies on the iterated processes of inference and inquiry. The inference phase consists of selecting the most probable models based on the available data; whereas the inquiry phase consists of using what is known about the models to select the most relevant experiment. Optimizing inquiry involves searching the parameterized space of experiments to select the experiment that promises, on average, to be maximally informative. In the case where it is important to learn about each of the model parameters, the relevance of an experiment is quantified by Shannon entropy of the distribution of experimental outcomes predicted by a probable set of models. If the set of potential experiments is described by many parameters, we must search this high-dimensional entropy space. Brute force search methods will be slow and computationally expensive. We present an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment for efficient experimental design. ...

  9. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2014-04-01

    This project (10/01/2010-9/30/2014), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This project will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. In this project, the focus is to develop and implement novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; perform material characterizations and oxidation/corrosion tests; and demonstrate our new thermal barrier coating (TBC) systems experimentally under integrated gasification combined cycle (IGCC) environments.

  10. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2012-10-01

    This project (10/01/2010-9/30/2013), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This project will directly support the technical goals specified in DEFOA- 0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. We will develop and implement novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; perform material characterizations and oxidation/corrosion tests; and demonstrate our new thermal barrier coating (TBC) systems experimentally under integrated gasification combined cycle (IGCC) environments. The durability of the coating will be examined using the proposed Durability Test Rig.

  11. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2014-04-01

    This project (10/01/2010-9/30/2014), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This project will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. In this project, the focus is to develop and implement novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; perform material characterizations and oxidation/corrosion tests; and demonstrate our new thermal barrier coating (TBC) systems experimentally under integrated gasification combined cycle (IGCC) environments.

  12. Acting like a physicist: Student approach study to experimental design

    Science.gov (United States)

    Karelina, Anna; Etkina, Eugenia

    2007-12-01

    National studies of science education have unanimously concluded that preparing our students for the demands of the 21st century workplace is one of the major goals. This paper describes a study of student activities in introductory college physics labs, which were designed to help students acquire abilities that are valuable in the workplace. In these labs [called Investigative Science Learning Environment (ISLE) labs], students design their own experiments. Our previous studies have shown that students in these labs acquire scientific abilities such as the ability to design an experiment to solve a problem, the ability to collect and analyze data, the ability to evaluate assumptions and uncertainties, and the ability to communicate. These studies mostly concentrated on analyzing students’ writing, evaluated by specially designed scientific ability rubrics. Recently, we started to study whether the ISLE labs make students not only write like scientists but also engage in discussions and act like scientists while doing the labs. For example, do students plan an experiment, validate assumptions, evaluate results, and revise the experiment if necessary? A brief report of some of our findings that came from monitoring students’ activity during ISLE and nondesign labs was presented in the Physics Education Research Conference Proceedings. We found differences in student behavior and discussions that indicated that ISLE labs do in fact encourage a scientistlike approach to experimental design and promote high-quality discussions. This paper presents a full description of the study.

  13. Current State of Agile User-Centered Design: A Survey

    Science.gov (United States)

    Hussain, Zahid; Slany, Wolfgang; Holzinger, Andreas

    Agile software development methods are quite popular nowadays and are being adopted at an increasing rate in the industry every year. However, these methods are still lacking usability awareness in their development lifecycle, and the integration of usability/User-Centered Design (UCD) into agile methods is not adequately addressed. This paper presents the preliminary results of a recently conducted online survey regarding the current state of the integration of agile methods and usability/UCD. A world wide response of 92 practitioners was received. The results show that the majority of practitioners perceive that the integration of agile methods with usability/UCD has added value to their adopted processes and to their teams; has resulted in the improvement of usability and quality of the product developed; and has increased the satisfaction of the end-users of the product developed. The top most used HCI techniques are low-fidelity prototyping, conceptual designs, observational studies of users, usability expert evaluations, field studies, personas, rapid iterative testing, and laboratory usability testing.

  14. DSM shareholder incentives: Current designs and economic theory

    Energy Technology Data Exchange (ETDEWEB)

    Stoft, S.; Eto, J.; Kito, S.

    1995-01-01

    This report reviews recent DSM shareholder incentive designs and performance at 10 US utilities identifies opportunities for regulators to improve the design of DSM shareholder incentive mechanisms to increase the procurement of cost-effective DSM resources. We develop six recommendations: (1) apply shared-savings incentives to DSM resource programs; (2) use markup incentives for individual programs only when net benefits are difficult to measure, but are known to be positive; (3) set expected incentive payments based on covering a utility`s {open_quotes}hidden costs,{close_quotes} which include some transitional management and risk-adjusted opportunity costs; (4) use higher marginal incentives rates than are currently found in practice, but limit total incentive payments by adding a fixed charge; (5) mitigate risks to regulators and utilities by lowering marginal incentive rates at high and low performance levels; and (6) use an aggregate incentive mechanism for all DSM resource programs, with limited exceptions (e.g., information programs where markups are more appropriate).

  15. Optimization of formulation variables of benzocaine liposomes using experimental design.

    Science.gov (United States)

    Mura, Paola; Capasso, Gaetano; Maestrelli, Francesca; Furlanetto, Sandra

    2008-01-01

    This study aimed to optimize, by means of an experimental design multivariate strategy, a liposomal formulation for topical delivery of the local anaesthetic agent benzocaine. The formulation variables for the vesicle lipid phase uses potassium glycyrrhizinate (KG) as an alternative to cholesterol and the addition of a cationic (stearylamine) or anionic (dicethylphosphate) surfactant (qualitative factors); the percents of ethanol and the total volume of the hydration phase (quantitative factors) were the variables for the hydrophilic phase. The combined influence of these factors on the considered responses (encapsulation efficiency (EE%) and percent drug permeated at 180 min (P%)) was evaluated by means of a D-optimal design strategy. Graphic analysis of the effects indicated that maximization of the selected responses requested opposite levels of the considered factors: For example, KG and stearylamine were better for increasing EE%, and cholesterol and dicethylphosphate for increasing P%. In the second step, the Doehlert design, applied for the response-surface study of the quantitative factors, pointed out a negative interaction between percent ethanol and volume of the hydration phase and allowed prediction of the best formulation for maximizing drug permeation rate. Experimental P% data of the optimized formulation were inside the confidence interval (P < 0.05) calculated around the predicted value of the response. This proved the suitability of the proposed approach for optimizing the composition of liposomal formulations and predicting the effects of formulation variables on the considered experimental response. Moreover, the optimized formulation enabled a significant improvement (P < 0.05) of the drug anaesthetic effect with respect to the starting reference liposomal formulation, thus demonstrating its actually better therapeutic effectiveness.

  16. Experimental system design for the integration of trapped-ion and superconducting qubit systems

    Science.gov (United States)

    De Motte, D.; Grounds, A. R.; Rehák, M.; Rodriguez Blanco, A.; Lekitsch, B.; Giri, G. S.; Neilinger, P.; Oelsner, G.; Il'ichev, E.; Grajcar, M.; Hensinger, W. K.

    2016-12-01

    We present a design for the experimental integration of ion trapping and superconducting qubit systems as a step towards the realization of a quantum hybrid system. The scheme addresses two key difficulties in realizing such a system: a combined microfabricated ion trap and superconducting qubit architecture, and the experimental infrastructure to facilitate both technologies. Developing upon work by Kielpinski et al. (Phys Rev Lett 108(13):130504, 2012. doi: 10.1103/PhysRevLett.108.130504), we describe the design, simulation and fabrication process for a microfabricated ion trap capable of coupling an ion to a superconducting microwave LC circuit with a coupling strength in the tens of kHz. We also describe existing difficulties in combining the experimental infrastructure of an ion trapping set-up into a dilution refrigerator with superconducting qubits and present solutions that can be immediately implemented using current technology.

  17. Designing artificial enzymes from scratch: Experimental study and mesoscale simulation

    Science.gov (United States)

    Komarov, Pavel V.; Zaborina, Olga E.; Klimova, Tamara P.; Lozinsky, Vladimir I.; Khalatur, Pavel G.; Khokhlov, Alexey R.

    2016-09-01

    We present a new concept for designing biomimetic analogs of enzymatic proteins; these analogs are based on the synthetic protein-like copolymers. α-Chymotrypsin is used as a prototype of the artificial catalyst. Our experimental study shows that in the course of free radical copolymerization of hydrophobic and hydrophilic monomers the target globular nanostructures of a "core-shell" morphology appear in a selective solvent. Using a mesoscale computer simulation, we show that the protein-like globules can have a large number of catalytic centers located at the hydrophobic core/hydrophilic shell interface.

  18. On the proper study design applicable to experimental balneology

    Science.gov (United States)

    Varga, Csaba

    2016-08-01

    The simple message of this paper is that it is the high time to reevaluate the strategies and optimize the efforts for investigation of thermal (spa) waters. Several articles trying to clear mode of action of medicinal waters have been published up to now. Almost all studies apply the unproven hypothesis, namely the inorganic ingredients are in close connection with healing effects of bathing. Change of paradigm would be highly necessary in this field taking into consideration the presence of several biologically active organic substances in these waters. A successful design for experimental mechanistic studies is approved.

  19. On the proper study design applicable to experimental balneology.

    Science.gov (United States)

    Varga, Csaba

    2016-08-01

    The simple message of this paper is that it is the high time to reevaluate the strategies and optimize the efforts for investigation of thermal (spa) waters. Several articles trying to clear mode of action of medicinal waters have been published up to now. Almost all studies apply the unproven hypothesis, namely the inorganic ingredients are in close connection with healing effects of bathing. Change of paradigm would be highly necessary in this field taking into consideration the presence of several biologically active organic substances in these waters. A successful design for experimental mechanistic studies is approved.

  20. Statistics for proteomics: experimental design and 2-DE differential analysis.

    Science.gov (United States)

    Chich, Jean-François; David, Olivier; Villers, Fanny; Schaeffer, Brigitte; Lutomski, Didier; Huet, Sylvie

    2007-04-15

    Proteomics relies on the separation of complex protein mixtures using bidimensional electrophoresis. This approach is largely used to detect the expression variations of proteins prepared from two or more samples. Recently, attention was drawn on the reliability of the results published in literature. Among the critical points identified were experimental design, differential analysis and the problem of missing data, all problems where statistics can be of help. Using examples and terms understandable by biologists, we describe how a collaboration between biologists and statisticians can improve reliability of results and confidence in conclusions.

  1. Experimental design methodology: the scientific tool for performance evaluation

    Science.gov (United States)

    Sadjadi, Firooz A.

    1990-09-01

    With the rapid growth of the signal and image processing technology in the last several decades has arisen the need for means of evaluating and comparing the numerous algorithms and systems that are created or are being developed. Performance evaluation, in the past, has been mostly ad hoc and incohesive. In this paper we present a systematic step by step approach for the scientific evaluation of signal and image processing algorithms and systems. This approach is based on the methodology of Experimental Design. We illustrate this method by means of an example from the field of automatic object recognition.

  2. Optimal experimental design to position transducers in ultrasound breast imaging

    Science.gov (United States)

    Korta Martiartu, Naiara; Boehm, Christian; Vinard, Nicolas; Jovanović Balic, Ivana; Fichtner, Andreas

    2017-03-01

    We present methods to optimize the setup of a 3D ultrasound tomography scanner for breast cancer detection. This approach provides a systematic and quantitative tool to evaluate different designs and to optimize the con- figuration with respect to predefined design parameters. We consider both, time-of-flight inversion using straight rays and time-domain waveform inversion governed by the acoustic wave equation for imaging the sound speed. In order to compare different designs, we measure their quality by extracting properties from the Hessian operator of the time-of-flight or waveform differences defined in the inverse problem, i.e., the second derivatives with respect to the sound speed. Spatial uncertainties and resolution can be related to the eigenvalues of the Hessian, which provide a good indication of the information contained in the data that is acquired with a given design. However, the complete spectrum is often prohibitively expensive to compute, thus suitable approximations have to be developed and analyzed. We use the trace of the Hessian operator as design criterion, which is equivalent to the sum of all eigenvalues and requires less computational effort. In addition, we suggest to take advantage of the spatial symmetry to extrapolate the 3D experimental design from a set of 2D configurations. In order to maximize the quality criterion, we use a genetic algorithm to explore the space of possible design configurations. Numerical results show that the proposed strategies are capable of improving an initial configuration with uniformly distributed transducers, clustering them around regions with poor illumination and improving the ray coverage of the domain of interest.

  3. Comparing Simulated Emission from Molecular Clouds Using Experimental Design

    CERN Document Server

    Yeremi, Miayan; Offner, Stella; Loeppky, Jason; Rosolowsky, Erik

    2014-01-01

    We propose a new approach to comparing simulated observations that enables us to determine the significance of the underlying physical effects. We utilize the methodology of experimental design, a subfield of statistical analysis, to establish a framework for comparing simulated position-position-velocity data cubes to each other. We propose three similarity metrics based on methods described in the literature: principal component analysis, the spectral correlation function, and the Cramer multi-variate two sample similarity statistic. Using these metrics, we intercompare a suite of mock observational data of molecular clouds generated from magnetohydrodynamic simulations with varying physical conditions. Using this framework, we show that all three metrics are sensitive to changing Mach number and temperature in the simulation sets, but cannot detect changes in magnetic field strength and initial velocity spectrum. We highlight the shortcomings of one-factor-at-a-time designs commonly used in astrophysics an...

  4. Parameters optimization for enzymatic assays using experimental design

    Directory of Open Access Journals (Sweden)

    J. F. M. Burkert

    2006-06-01

    Full Text Available The conditions for maximization enzymatic activity were determined using experimental design and inulinase from Kluyveromyces marxianus ATCC 16045. The effects of substrate concentration (sucrose and inulin, pH and temperature on inulinase activity were verified using four factorial design and surface response analysis. Using sucrose as substrate. It has bean shown that the effects sucrose on enzymatic activity is not statistically significant and the best condition for the highest activity (110 U/mL was achieved with temperature between 60°C and 68°C and pH between 4.5 and 5.0. Using inulin as substrate it was verified that temperature is the only variable statistically significant and the maximum activity was 7.3 U/mL at temperature between 50°C and 51°C.

  5. Bayesian experimental design for models with intractable likelihoods.

    Science.gov (United States)

    Drovandi, Christopher C; Pettitt, Anthony N

    2013-12-01

    In this paper we present a methodology for designing experiments for efficiently estimating the parameters of models with computationally intractable likelihoods. The approach combines a commonly used methodology for robust experimental design, based on Markov chain Monte Carlo sampling, with approximate Bayesian computation (ABC) to ensure that no likelihood evaluations are required. The utility function considered for precise parameter estimation is based upon the precision of the ABC posterior distribution, which we form efficiently via the ABC rejection algorithm based on pre-computed model simulations. Our focus is on stochastic models and, in particular, we investigate the methodology for Markov process models of epidemics and macroparasite population evolution. The macroparasite example involves a multivariate process and we assess the loss of information from not observing all variables.

  6. Experimental identification of an azimuthal current in a magnetic nozzle of a radiofrequency plasma thruster

    Science.gov (United States)

    Takahashi, Kazunori; Chiba, Aiki; Komuro, Atsushi; Ando, Akira

    2016-10-01

    The azimuthal plasma current in a magnetic nozzle of a radiofrequency plasma thruster is experimentally identified by measuring the plasma-induced magnetic field. The axial plasma momentum increases over about 20 cm downstream of the thruster exit due to the Lorentz force arising from the azimuthal current. The measured current shows that the azimuthal current is given by the sum of the electron diamagnetic drift and \\mathbf{E}× \\mathbf{B} drift currents, where the latter component decreases with an increase in the magnetic field strength; hence the azimuthal current approaches the electron diamagnetic drift one for the strong magnetic field. The Lorentz force calculated from the measured azimuthal plasma current and the radial magnetic field is smaller than the directly measured force exerted to the magnetic field, which indicates the existence of a non-negligible Lorentz force in the source tube.

  7. Design of Experimental Suspended Footbridge with Deck Made of UHPC

    Directory of Open Access Journals (Sweden)

    Blank Marek

    2016-01-01

    Full Text Available This paper deals with the static and dynamic design of experimental footbridge for pedestrians and cyclists in the municipality Lužec nad Vltavou in Czech Republic, Europe. This work aims to familiarize the reader with calculations carried out and the results obtained, describing the static and dynamic properties of proposed footbridge. The construction of footbridge is designed as a suspended structure with prestressed bridge deck consisting of prefabricated UHPC panels and reversed “V” shaped steel pylon with height of approximately 40 meters. The deck is anchored using 24 steel hangers in one row in a steel pylon - 17 ropes in the main span and 7 cables on the other side. Range of the main span is 99.18 meters and the secondary span is 31.9 m. Deck width is 4.5 meters with 3.0 meters passing space. The bridge is designed for the possibility of passage of vehicles weighting up to 3.5 tons. Deck panels are made of UHPC with reinforcement. At the edge of the bridge on the side of the shorter span the bridge deck is firmly connected with abutment and on the other deck it is stored using a pair of sliding bearings. The utilization of the excellent properties of UHPC allows to design a very thin and lightweight construction of the deck, which could not be achieved with the use of normal concrete.

  8. Logical Experimental Design and Execution in the Biomedical Sciences.

    Science.gov (United States)

    Holder, Daniel J; Marino, Michael J

    2017-03-17

    Lack of reproducibility has been highlighted as a significant problem in biomedical research. The present unit is devoted to describing ways to help ensure that research findings can be replicated by others, with a focus on the design and execution of laboratory experiments. Essential components for this include clearly defining the question being asked, using available information or information from pilot studies to aid in the design the experiment, and choosing manipulations under a logical framework based on Mill's "methods of knowing" to build confidence in putative causal links. Final experimental design requires systematic attention to detail, including the choice of controls, sample selection, blinding to avoid bias, and the use of power analysis to determine the sample size. Execution of the experiment is done with care to ensure that the independent variables are controlled and the measurements of the dependent variables are accurate. While there are always differences among laboratories with respect to technical expertise, equipment, and suppliers, execution of the steps itemized in this unit will ensure well-designed and well-executed experiments to answer any question in biomedical research. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

  9. Water-waves on linear shear currents. A comparison of experimental and numerical results.

    Science.gov (United States)

    Simon, Bruno; Seez, William; Touboul, Julien; Rey, Vincent; Abid, Malek; Kharif, Christian

    2016-04-01

    Propagation of water waves can be described for uniformly sheared current conditions. Indeed, some mathematical simplifications remain applicable in the study of waves whether there is no current or a linearly sheared current. However, the widespread use of mathematical wave theories including shear has rarely been backed by experimental studies of such flows. New experimental and numerical methods were both recently developed to study wave current interactions for constant vorticity. On one hand, the numerical code can simulate, in two dimensions, arbitrary non-linear waves. On the other hand, the experimental methods can be used to generate waves with various shear conditions. Taking advantage of the simplicity of the experimental protocol and versatility of the numerical code, comparisons between experimental and numerical data are discussed and compared with linear theory for validation of the methods. ACKNOWLEDGEMENTS The DGA (Direction Générale de l'Armement, France) is acknowledged for its financial support through the ANR grant N° ANR-13-ASTR-0007.

  10. Experimental Evaluation of Three Designs of Electrodynamic Flexural Transducers

    Science.gov (United States)

    Eriksson, Tobias J. R.; Laws, Michael; Kang, Lei; Fan, Yichao; Ramadas, Sivaram N.; Dixon, Steve

    2016-01-01

    Three designs for electrodynamic flexural transducers (EDFT) for air-coupled ultrasonics are presented and compared. An all-metal housing was used for robustness, which makes the designs more suitable for industrial applications. The housing is designed such that there is a thin metal plate at the front, with a fundamental flexural vibration mode at ∼50 kHz. By using a flexural resonance mode, good coupling to the load medium was achieved without the use of matching layers. The front radiating plate is actuated electrodynamically by a spiral coil inside the transducer, which produces an induced magnetic field when an AC current is applied to it. The transducers operate without the use of piezoelectric materials, which can simplify manufacturing and prolong the lifetime of the transducers, as well as open up possibilities for high-temperature applications. The results show that different designs perform best for the generation and reception of ultrasound. All three designs produced large acoustic pressure outputs, with a recorded sound pressure level (SPL) above 120 dB at a 40 cm distance from the highest output transducer. The sensitivity of the transducers was low, however, with single shot signal-to-noise ratio (SNR)≃15 dB in transmit–receive mode, with transmitter and receiver 40 cm apart. PMID:27571075

  11. Fast Bayesian optimal experimental design for seismic source inversion

    KAUST Repository

    Long, Quan

    2015-07-01

    We develop a fast method for optimally designing experiments in the context of statistical seismic source inversion. In particular, we efficiently compute the optimal number and locations of the receivers or seismographs. The seismic source is modeled by a point moment tensor multiplied by a time-dependent function. The parameters include the source location, moment tensor components, and start time and frequency in the time function. The forward problem is modeled by elastodynamic wave equations. We show that the Hessian of the cost functional, which is usually defined as the square of the weighted L2 norm of the difference between the experimental data and the simulated data, is proportional to the measurement time and the number of receivers. Consequently, the posterior distribution of the parameters, in a Bayesian setting, concentrates around the "true" parameters, and we can employ Laplace approximation and speed up the estimation of the expected Kullback-Leibler divergence (expected information gain), the optimality criterion in the experimental design procedure. Since the source parameters span several magnitudes, we use a scaling matrix for efficient control of the condition number of the original Hessian matrix. We use a second-order accurate finite difference method to compute the Hessian matrix and either sparse quadrature or Monte Carlo sampling to carry out numerical integration. We demonstrate the efficiency, accuracy, and applicability of our method on a two-dimensional seismic source inversion problem. © 2015 Elsevier B.V.

  12. Prediction uncertainty and optimal experimental design for learning dynamical systems

    Science.gov (United States)

    Letham, Benjamin; Letham, Portia A.; Rudin, Cynthia; Browne, Edward P.

    2016-06-01

    Dynamical systems are frequently used to model biological systems. When these models are fit to data, it is necessary to ascertain the uncertainty in the model fit. Here, we present prediction deviation, a metric of uncertainty that determines the extent to which observed data have constrained the model's predictions. This is accomplished by solving an optimization problem that searches for a pair of models that each provides a good fit for the observed data, yet has maximally different predictions. We develop a method for estimating a priori the impact that additional experiments would have on the prediction deviation, allowing the experimenter to design a set of experiments that would most reduce uncertainty. We use prediction deviation to assess uncertainty in a model of interferon-alpha inhibition of viral infection, and to select a sequence of experiments that reduces this uncertainty. Finally, we prove a theoretical result which shows that prediction deviation provides bounds on the trajectories of the underlying true model. These results show that prediction deviation is a meaningful metric of uncertainty that can be used for optimal experimental design.

  13. Fast Bayesian Optimal Experimental Design for Seismic Source Inversion

    KAUST Repository

    Long, Quan

    2016-01-06

    We develop a fast method for optimally designing experiments [1] in the context of statistical seismic source inversion [2]. In particular, we efficiently compute the optimal number and locations of the receivers or seismographs. The seismic source is modeled by a point moment tensor multiplied by a time-dependent function. The parameters include the source location, moment tensor components, and start time and frequency in the time function. The forward problem is modeled by the elastic wave equations. We show that the Hessian of the cost functional, which is usually defined as the square of the weighted L2 norm of the difference between the experimental data and the simulated data, is proportional to the measurement time and the number of receivers. Consequently, the posterior distribution of the parameters, in a Bayesian setting, concentrates around the true parameters, and we can employ Laplace approximation and speed up the estimation of the expected Kullback-Leibler divergence (expected information gain), the optimality criterion in the experimental design procedure. Since the source parameters span several magnitudes, we use a scaling matrix for efficient control of the condition number of the original Hessian matrix. We use a second-order accurate finite difference method to compute the Hessian matrix and either sparse quadrature or Monte Carlo sampling to carry out numerical integration. We demonstrate the efficiency, accuracy, and applicability of our method on a two-dimensional seismic source inversion problem.

  14. Experimental study of elementary collection efficiency of aerosols by spray: Design of the experimental device

    Energy Technology Data Exchange (ETDEWEB)

    Ducret, D.; Vendel, J.; Garrec. S.L.

    1995-02-01

    The safety of a nuclear power plant containment building, in which pressure and temperature could increase because of a overheating reactor accident, can be achieved by spraying water drops. The spray reduces the pressure and the temperature levels by condensation of steam on cold water drops. The more stringent thermodynamic conditions are a pressure of 5.10{sup 5} Pa (due to steam emission) and a temperature of 413 K. Moreover its energy dissipation function, the spray leads to the washout of fission product particles emitted in the reactor building atmosphere. The present study includes a large program devoted to the evaluation of realistic washout rates. The aim of this work is to develop experiments in order to determine the collection efficiency of aerosols by a single drop. To do this, the experimental device has to be designed with fundamental criteria:-Thermodynamic conditions have to be representative of post-accident atmosphere. Thermodynamic equilibrium has to be attained between the water drops and the gaseous phase. Thermophoretic, diffusiophoretic and mechanical effects have to be studied independently. Operating conditions have to be homogenous and constant during each experiment. This paper presents the design of the experimental device. In practice, the consequences on the design of each of the criteria given previously and the necessity of being representative of the real conditions will be described.

  15. Advanced computational tools for PEM fuel cell design. Part 2. Detailed experimental validation and parametric study

    Science.gov (United States)

    Sui, P. C.; Kumar, S.; Djilali, N.

    This paper reports on the systematic experimental validation of a comprehensive 3D CFD-based computational model presented and documented in Part 1. Simulations for unit cells with straight channels, similar to the Ballard Mk902 hardware, are performed and analyzed in conjunction with detailed current mapping measurements and water mass distributions in the membrane-electrode assembly. The experiments were designed to display sensitivity of the cell over a range of operating parameters including current density, humidification, and coolant temperature, making the data particularly well suited for systematic validation. Based on the validation and analysis of the predictions, values of model parameters, including the electro-osmotic drag coefficient, capillary diffusion coefficient, and catalyst specific surface area are determined adjusted to fit experimental data of current density and MEA water content. The predicted net water flux out of the anode (normalized by the total water generated) increases as anode humidification water flow rate is increased, in agreement with experimental results. A modification of the constitutive equation for the capillary diffusivity of water in the porous electrodes that attempts to incorporate the experimentally observed immobile (or irreducible) saturation yields a better fit of the predicted MEA water mass with experimental data. The specific surface area parameter used in the catalyst layer model is found to be effective in tuning the simulations to predict the correct cell voltage over a range of stoichiometries.

  16. Experimental Design for the INL Sample Collection Operational Test

    Energy Technology Data Exchange (ETDEWEB)

    Amidan, Brett G.; Piepel, Gregory F.; Matzke, Brett D.; Filliben, James J.; Jones, Barbara

    2007-12-13

    This document describes the test events and numbers of samples comprising the experimental design that was developed for the contamination, decontamination, and sampling of a building at the Idaho National Laboratory (INL). This study is referred to as the INL Sample Collection Operational Test. Specific objectives were developed to guide the construction of the experimental design. The main objective is to assess the relative abilities of judgmental and probabilistic sampling strategies to detect contamination in individual rooms or on a whole floor of the INL building. A second objective is to assess the use of probabilistic and Bayesian (judgmental + probabilistic) sampling strategies to make clearance statements of the form “X% confidence that at least Y% of a room (or floor of the building) is not contaminated. The experimental design described in this report includes five test events. The test events (i) vary the floor of the building on which the contaminant will be released, (ii) provide for varying or adjusting the concentration of contaminant released to obtain the ideal concentration gradient across a floor of the building, and (iii) investigate overt as well as covert release of contaminants. The ideal contaminant gradient would have high concentrations of contaminant in rooms near the release point, with concentrations decreasing to zero in rooms at the opposite end of the building floor. For each of the five test events, the specified floor of the INL building will be contaminated with BG, a stand-in for Bacillus anthracis. The BG contaminant will be disseminated from a point-release device located in the room specified in the experimental design for each test event. Then judgmental and probabilistic samples will be collected according to the pre-specified sampling plan. Judgmental samples will be selected based on professional judgment and prior information. Probabilistic samples will be selected in sufficient numbers to provide desired confidence

  17. Bayesian optimal experimental design for priors of compact support

    KAUST Repository

    Long, Quan

    2016-01-08

    In this study, we optimize the experimental setup computationally by optimal experimental design (OED) in a Bayesian framework. We approximate the posterior probability density functions (pdf) using truncated Gaussian distributions in order to account for the bounded domain of the uniform prior pdf of the parameters. The underlying Gaussian distribution is obtained in the spirit of the Laplace method, more precisely, the mode is chosen as the maximum a posteriori (MAP) estimate, and the covariance is chosen as the negative inverse of the Hessian of the misfit function at the MAP estimate. The model related entities are obtained from a polynomial surrogate. The optimality, quantified by the information gain measures, can be estimated efficiently by a rejection sampling algorithm against the underlying Gaussian probability distribution, rather than against the true posterior. This approach offers a significant error reduction when the magnitude of the invariants of the posterior covariance are comparable to the size of the bounded domain of the prior. We demonstrate the accuracy and superior computational efficiency of our method for shock-tube experiments aiming to measure the model parameters of a key reaction which is part of the complex kinetic network describing the hydrocarbon oxidation. In the experiments, the initial temperature and fuel concentration are optimized with respect to the expected information gain in the estimation of the parameters of the target reaction rate. We show that the expected information gain surface can change its shape dramatically according to the level of noise introduced into the synthetic data. The information that can be extracted from the data saturates as a logarithmic function of the number of experiments, and few experiments are needed when they are conducted at the optimal experimental design conditions.

  18. Experimental design in phylogenetics: testing predictions from expected information.

    Science.gov (United States)

    San Mauro, Diego; Gower, David J; Cotton, James A; Zardoya, Rafael; Wilkinson, Mark; Massingham, Tim

    2012-07-01

    Taxon and character sampling are central to phylogenetic experimental design; yet, we lack general rules. Goldman introduced a method to construct efficient sampling designs in phylogenetics, based on the calculation of expected Fisher information given a probabilistic model of sequence evolution. The considerable potential of this approach remains largely unexplored. In an earlier study, we applied Goldman's method to a problem in the phylogenetics of caecilian amphibians and made an a priori evaluation and testable predictions of which taxon additions would increase information about a particular weakly supported branch of the caecilian phylogeny by the greatest amount. We have now gathered mitogenomic and rag1 sequences (some newly determined for this study) from additional caecilian species and studied how information (both expected and observed) and bootstrap support vary as each new taxon is individually added to our previous data set. This provides the first empirical test of specific predictions made using Goldman's method for phylogenetic experimental design. Our results empirically validate the top 3 (more intuitive) taxon addition predictions made in our previous study, but only information results validate unambiguously the 4th (less intuitive) prediction. This highlights a complex relationship between information and support, reflecting that each measures different things: Information is related to the ability to estimate branch length accurately and support to the ability to estimate the tree topology accurately. Thus, an increase in information may be correlated with but does not necessitate an increase in support. Our results also provide the first empirical validation of the widely held intuition that additional taxa that join the tree proximal to poorly supported internal branches are more informative and enhance support more than additional taxa that join the tree more distally. Our work supports the view that adding more data for a single (well

  19. Modeling and Controller Design of PV Micro Inverter without Using Electrolytic Capacitors and Input Current Sensors

    Directory of Open Access Journals (Sweden)

    Faa Jeng Lin

    2016-11-01

    Full Text Available This paper outlines the modeling and controller design of a novel two-stage photovoltaic (PV micro inverter (MI that eliminates the need for an electrolytic capacitor (E-cap and input current sensor. The proposed MI uses an active-clamped current-fed push-pull DC-DC converter, cascaded with a full-bridge inverter. Three strategies are proposed to cope with the inherent limitations of a two-stage PV MI: (i high-speed DC bus voltage regulation using an integrator to deal with the 2nd harmonic voltage ripples found in single-phase systems; (ii inclusion of a small film capacitor in the DC bus to achieve ripple-free PV voltage; (iii improved incremental conductance (INC maximum power point tracking (MPPT without the need for current sensing by the PV module. Simulation and experimental results demonstrate the efficacy of the proposed system.

  20. New approaches in the design of magnetic tweezers-current magnetic tweezers

    Science.gov (United States)

    Bessalova, Valentina; Perov, Nikolai; Rodionova, Valeria

    2016-10-01

    The main advantages of the magnetic tweezers are the low price and simplicity of use. However the range of their application is reduced due to shortcomings like, for example, the remanent induction of the core and interaction between ferromagnetic cores. We present the new design of magnetic tweezers-Current Magnetic Tweezers (CMT) that allow particle manipulation by means of the magnetic field generated by the electric currents flowing through the non-magnetic wires. Arranging wires in different geometric shapes allows the particle movement either in two or three dimensions. Forces acting on the magnetic particles with the magnetic moment of 2·10-11 A m2 at distances up to 1 mm had been experimentally measured. It is established that a current of about 1 A at a 1 mm distance generates force of (approximately) 3 pN which is consistent with theoretical estimates.

  1. An interactive visualization tool and data model for experimental design in systems biology.

    Science.gov (United States)

    Kapoor, Shray; Quo, Chang Feng; Merrill, Alfred H; Wang, May D

    2008-01-01

    Experimental design is important, but is often under-supported, in systems biology research. To improve experimental design, we extend the visualization of complex sphingolipid pathways to study biosynthetic origin in SphinGOMAP. We use the ganglio-series sphingolipid dataset as a test bed and the Java Universal Network / Graph Framework (JUNG) visualization toolkit. The result is an interactive visualization tool and data model for experimental design in lipid systems biology research. We improve the current SphinGOMAP in terms of interactive visualization by allowing (i) choice of four different network layouts, (ii) dynamic addition / deletion of on-screen molecules and (iii) mouse-over to reveal detailed molecule data. Future work will focus on integrating various lipid-relevant data systematically i.e. SphinGOMAP biosynthetic data, Lipid Bank molecular data (Japan) and Lipid MAPS metabolic pathway data (USA). We aim to build a comprehensive and interactive communication platform to improve experimental design for scientists globally in high-throughput lipid systems biology research.

  2. Tritium processing for the European test blanket systems: current status of the design and development strategy

    Energy Technology Data Exchange (ETDEWEB)

    Ricapito, I.; Calderoni, P.; Poitevin, Y. [Fusion for Energy, Barcelona (Spain); Aiello, A.; Utili, M. [ENEA, Camugnano (Italy); Demange, D. [Karlsruhe Institute of Technology - KIT, Karlsruhe (Germany)

    2015-03-15

    Tritium processing technologies of the two European Test Blanket Systems (TBS), HCLL (Helium Cooled Lithium Lead) and HCPB (Helium Cooled Pebble Bed), play an essential role in meeting the main objectives of the TBS experimental campaign in ITER. The compliancy with the ITER interface requirements, in terms of space availability, service fluids, limits on tritium release, constraints on maintenance, is driving the design of the TBS tritium processing systems. Other requirements come from the characteristics of the relevant test blanket module and the scientific programme that has to be developed and implemented. This paper identifies the main requirements for the design of the TBS tritium systems and equipment and, at the same time, provides an updated overview on the current design status, mainly focusing onto the tritium extractor from Pb-16Li and TBS tritium accountancy. Considerations are also given on the possible extrapolation to DEMO breeding blanket. (authors)

  3. Correlates of experimentation with smoking and current cigarette consumption among adolescents

    Directory of Open Access Journals (Sweden)

    Amanda Gimenes Bonilha

    2014-12-01

    Full Text Available OBJECTIVE: The aim of this study was to analyze social characteristics and stress as correlates of cigarette smoking in adolescence. The main intent was to identify elements that distinguish adolescents who had experimented with smoking and did not progress to regular smoking from those who became current smokers. METHODS: Students at 10 high schools in the city of Ribeirão Preto, Brazil, completed a questionnaire based on an instrument employed in a similar large-scale study. The students were classified as never-smokers or experimenters. The experimenters were subcategorized as having become current smokers or nonprogressors. Analyses were performed using adjusted logistic models. RESULTS: A total of 2,014 students (mean age, 16.2 ± 1.1 years; females, 53% completed the questionnaire. We categorized 1,283 students (63.7% as never-smokers, 244 (12.1% as current smokers, and 487 (24.2% as nonprogressors. We found that experimentation with smoking was associated with being held back a grade in school (OR = 1.80, alcohol intake (low/occasional, OR = 8.92; high/regular, OR = 2.64, illicit drug use (OR = 9.32, having a sibling or cousin who smokes (OR = 1.39, having a friend who smokes (OR = 2.08, and high levels of stress (in females only, OR = 1.32. Factors associated with an increased risk of transitioning from experimenter to current smoker were alcohol intake (low/occasional, OR = 3.28; high/regular, OR = 2.16, illicit drug use (OR = 3.61, and having a friend who smokes (OR = 7.20. CONCLUSIONS: Current smoking was associated with a profile of socioeconomic correlates different from that associated with experimentation only. Our data (showing that current smoking was associated with having a friend who smokes, alcohol intake, and illicit drug use suggest the need for comprehensive approaches to discourage substance use during adolescence.

  4. Comparing simulated emission from molecular clouds using experimental design

    Energy Technology Data Exchange (ETDEWEB)

    Yeremi, Miayan; Flynn, Mallory; Loeppky, Jason; Rosolowsky, Erik [University of British Columbia, Okanagan Campus, Departments of Physics and Statistics, 3333 University Way, Kelowna BC V1V 1V7 (Canada); Offner, Stella [Yale University Astronomy Department, 260 Whitney Avenue, New Haven, CT 06511 (United States)

    2014-03-10

    We propose a new approach to comparing simulated observations that enables us to determine the significance of the underlying physical effects. We utilize the methodology of experimental design, a subfield of statistical analysis, to establish a framework for comparing simulated position-position-velocity data cubes to each other. We propose three similarity metrics based on methods described in the literature: principal component analysis, the spectral correlation function, and the Cramer multi-variate two-sample similarity statistic. Using these metrics, we intercompare a suite of mock observational data of molecular clouds generated from magnetohydrodynamic simulations with varying physical conditions. Using this framework, we show that all three metrics are sensitive to changing Mach number and temperature in the simulation sets, but cannot detect changes in magnetic field strength and initial velocity spectrum. We highlight the shortcomings of one-factor-at-a-time designs commonly used in astrophysics and propose fractional factorial designs as a means to rigorously examine the effects of changing physical properties while minimizing the investment of computational resources.

  5. Complementary numerical–experimental benchmarking for shape optimization and validation of structures subjected to wave and current forces

    DEFF Research Database (Denmark)

    Markus, D.; Ferri, Francesco; Wüchner, R.

    2015-01-01

    that focuses on differences in load curves resulting from 2D and 3D flows. It is shown that the major trends predicted by the numerical simulations are also captured in the experiment, highlighting the potential of CFD as a powerful tool for shape optimization studies. The overall aim of the paper...... variations of the structure on the resulting horizontal forces. Steady current conditions, dynamic loading due to waves, and combined wave–current scenarios are considered. A clear focus is put on simplicity and reproducibility, allowing for efficient testing of related methods and codes. This is achieved...... by defining a simple test geometry, altered in one design variable only, and by designing the test case such that a two dimensional analysis of the flow fields is possible. The force sensitivities to changes in the geometry are determined both numerically and experimentally for a great bandwidth of different...

  6. Design and Performance of a Novel Pancake Rogowski Coil for Measuring Pulse Currents%Design and Performance of a Novel Pancake Rogowski Coil for Measuring Pulse Currents

    Institute of Scientific and Technical Information of China (English)

    王春杰; 汲胜昌; 聂济宇; 欧小波; 韩钟健; 张乔根

    2011-01-01

    A novel pancake Rogowski coil without magnetic core is introduced in this paper. Owing to its special pancake winding structure, the coil is of low self-resistance and high self-inductance, and thus has excellent low frequency characteristic in the self-integral mode. Moreover, because of its unique installation method, the coil has a flexible sensitivity and can be applied under situations where toroidal air-core Rogowski coils or printed aircuit board (PCB) coils are not available. The parameters and performance of the pancake Rogowski coil are presented, and the principle of shielding is given. Measurements of step pulse current and oscillating pulse current by the coil are studied experimentally to illustrate its good linearity, reliable and flexible sensitivity and excellent frequency characteristic, especially its advantage in low frequency characteristic. The pancake Rogowski coil can be designed to assume round, square or rectangle shape, and has thus broad prospects in its application to the current measurement in such areas as plasma physics and pulsed power technology.

  7. Experimental observations of stray current effects on steel fibres embedded in mortar

    DEFF Research Database (Denmark)

    Solgaard, A.O.S.; Carsana, M.; Geiker, M.R.;

    2013-01-01

    It is known that stray direct current can cause corrosive damage over time to bar reinforced concrete, but knowledge on the consequences to steel fibre reinforced concrete is limited. This paper presents analyses and corresponding results from an experimental program (parametric study) investigat...

  8. Experimental Results on Current-Driven Turbulence in Plasmas - a Survey

    NARCIS (Netherlands)

    Dekluiver, H.; Perepelkin, N. F.; Hirose, A.

    1991-01-01

    The experimental consequences of plasma turbulence driven by a current parallel to a magnetic field and concurrent anomalous plasma heating are reviewed, with an attempt to deduce universalities in key parameters such as the anomalous electrical conductivities observed in diverse devices. It has

  9. Design, experimentation, and modeling of a novel continuous biodrying process

    Science.gov (United States)

    Navaee-Ardeh, Shahram

    Massive production of sludge in the pulp and paper industry has made the effective sludge management increasingly a critical issue for the industry due to high landfill and transportation costs, and complex regulatory frameworks for options such as sludge landspreading and composting. Sludge dewatering challenges are exacerbated at many mills due to improved in-plant fiber recovery coupled with increased production of secondary sludge, leading to a mixed sludge with a high proportion of biological matter which is difficult to dewater. In this thesis, a novel continuous biodrying reactor was designed and developed for drying pulp and paper mixed sludge to economic dry solids level so that the dried sludge can be economically and safely combusted in a biomass boiler for energy recovery. In all experimental runs the economic dry solids level was achieved, proving the process successful. In the biodrying process, in addition to the forced aeration, the drying rates are enhanced by biological heat generated through the microbial activity of mesophilic and thermophilic microorganisms naturally present in the porous matrix of mixed sludge. This makes the biodrying process more attractive compared to the conventional drying techniques because the reactor is a self-heating process. The reactor is divided into four nominal compartments and the mixed sludge dries as it moves downward in the reactor. The residence times were 4-8 days, which are 2-3 times shorter than the residence times achieved in a batch biodrying reactor previously studied by our research group for mixed sludge drying. A process variable analysis was performed to determine the key variable(s) in the continuous biodrying reactor. Several variables were investigated, namely: type of biomass feed, pH of biomass, nutrition level (C/N ratio), residence times, recycle ratio of biodried sludge, and outlet relative humidity profile along the reactor height. The key variables that were identified in the continuous

  10. The ISR Asymmetrical Capacitor Thruster: Experimental Results and Improved Designs

    Science.gov (United States)

    Canning, Francis X.; Cole, John; Campbell, Jonathan; Winet, Edwin

    2004-01-01

    A variety of Asymmetrical Capacitor Thrusters has been built and tested at the Institute for Scientific Research (ISR). The thrust produced for various voltages has been measured, along with the current flowing, both between the plates and to ground through the air (or other gas). VHF radiation due to Trichel pulses has been measured and correlated over short time scales to the current flowing through the capacitor. A series of designs were tested, which were increasingly efficient. Sharp features on the leading capacitor surface (e.g., a disk) were found to increase the thrust. Surprisingly, combining that with sharp wires on the trailing edge of the device produced the largest thrust. Tests were performed for both polarizations of the applied voltage, and for grounding one or the other capacitor plate. In general (but not always) it was found that the direction of the thrust depended on the asymmetry of the capacitor rather than on the polarization of the voltage. While no force was measured in a vacuum, some suggested design changes are given for operation in reduced pressures.

  11. EXPERIMENTAL RESEARCH REGARDING LEATHER APPLICATIONS IN PRODUCT DESIGN

    Directory of Open Access Journals (Sweden)

    PRALEA Jeni

    2015-05-01

    Full Text Available This paper presents the role and importance of experimental research in design activity. The designer, as a researcher and a project manager, proposes to establish a relationship between functional-aesthetic-constructive-technological-economic,based on the aesthetic possibilities of the materials used for the experiments. With the aim to identify areas for the application of leather waste resulted from the production process, the paper presents experiments conducted with this material in combination with wood, by using different techniques that lead to different aesthetic effects. Identifying the areas to use and creating products from leather and/or wood waste, is based on the properties of these materials. Leather, the subject of these experiments, has the advantage that it can be used on both sides. Tactile differences of the two sides of this material has both aesthetical and functional advantages, which makes it suitable for applications on products that meet the requirements of "design for all". With differentiated tactile characteristics, in combination with other materials, for these experiments wood, easily "read touch" products can be generated to help people with certain disabilities. Thus, experiments presented in this paper allows the establishment of aesthetic schemes applicable to products that are friendly both with the environment (based on the reuse of wood and leather waste and with the users (can be used as applications, accessories and concepts of products for people with certain disabilities. The designer’s choices or decisions can be based on the results of this experiment. The experiment enables the designer to develop creative, innovative and environmentally friendly products.

  12. Bayesian Optimal Experimental Design Using Multilevel Monte Carlo

    KAUST Repository

    Ben Issaid, Chaouki

    2015-05-12

    Experimental design can be vital when experiments are resource-exhaustive and time-consuming. In this work, we carry out experimental design in the Bayesian framework. To measure the amount of information that can be extracted from the data in an experiment, we use the expected information gain as the utility function, which specifically is the expected logarithmic ratio between the posterior and prior distributions. Optimizing this utility function enables us to design experiments that yield the most informative data about the model parameters. One of the major difficulties in evaluating the expected information gain is that it naturally involves nested integration over a possibly high dimensional domain. We use the Multilevel Monte Carlo (MLMC) method to accelerate the computation of the nested high dimensional integral. The advantages are twofold. First, MLMC can significantly reduce the cost of the nested integral for a given tolerance, by using an optimal sample distribution among different sample averages of the inner integrals. Second, the MLMC method imposes fewer assumptions, such as the asymptotic concentration of posterior measures, required for instance by the Laplace approximation (LA). We test the MLMC method using two numerical examples. The first example is the design of sensor deployment for a Darcy flow problem governed by a one-dimensional Poisson equation. We place the sensors in the locations where the pressure is measured, and we model the conductivity field as a piecewise constant random vector with two parameters. The second one is chemical Enhanced Oil Recovery (EOR) core flooding experiment assuming homogeneous permeability. We measure the cumulative oil recovery, from a horizontal core flooded by water, surfactant and polymer, for different injection rates. The model parameters consist of the endpoint relative permeabilities, the residual saturations and the relative permeability exponents for the three phases: water, oil and

  13. Design and construction of the IEA Grimethorpe experimental facility

    Energy Technology Data Exchange (ETDEWEB)

    Broadbent, D.H.; Wright, S.J.; Kaden, M.

    1979-06-01

    In December 1975 the Governments of the United Kingdom, the United States of America, and the Federal Republic of Germany, under the auspices of the International Energy Agency, entered into an agreement to build a large pressurized fluidized bed combustion experimental facility. The function of the facility would be to extend the range of fluidization and combustion characteristics investigated from those of the relatively small rigs then in operation across the whole range of conditions potentially applicable to combined cycle power generation systems. The ranges of conditions to be investigated in the facility are pressures 6 to 12 bar, fluidizing velocity 0.6 to 3.0 m/s and bed temperatures 750 to 950/sup 0/C. The ultimate aim is to seek an optimum condition and establish a data base from which a demonstration plant could be designed and built.

  14. Statistics in experimental design, preprocessing, and analysis of proteomics data.

    Science.gov (United States)

    Jung, Klaus

    2011-01-01

    High-throughput experiments in proteomics, such as 2-dimensional gel electrophoresis (2-DE) and mass spectrometry (MS), yield usually high-dimensional data sets of expression values for hundreds or thousands of proteins which are, however, observed on only a relatively small number of biological samples. Statistical methods for the planning and analysis of experiments are important to avoid false conclusions and to receive tenable results. In this chapter, the most frequent experimental designs for proteomics experiments are illustrated. In particular, focus is put on studies for the detection of differentially regulated proteins. Furthermore, issues of sample size planning, statistical analysis of expression levels as well as methods for data preprocessing are covered.

  15. An experimental design method leading to chemical Turing patterns.

    Science.gov (United States)

    Horváth, Judit; Szalai, István; De Kepper, Patrick

    2009-05-08

    Chemical reaction-diffusion patterns often serve as prototypes for pattern formation in living systems, but only two isothermal single-phase reaction systems have produced sustained stationary reaction-diffusion patterns so far. We designed an experimental method to search for additional systems on the basis of three steps: (i) generate spatial bistability by operating autoactivated reactions in open spatial reactors; (ii) use an independent negative-feedback species to produce spatiotemporal oscillations; and (iii) induce a space-scale separation of the activatory and inhibitory processes with a low-mobility complexing agent. We successfully applied this method to a hydrogen-ion autoactivated reaction, the thiourea-iodate-sulfite (TuIS) reaction, and noticeably produced stationary hexagonal arrays of spots and parallel stripes of pH patterns attributed to a Turing bifurcation. This method could be extended to biochemical reactions.

  16. SUSY effects in $R_b$: revisited under current experimental constraints

    CERN Document Server

    Su, Wei

    2016-01-01

    In this note we revisit the effects of natural SUSY in $R_b$ under current experimental constraints including the LHC Higgs data, the $B$-physics measurements, the dark matter relic density and direct detection limits, as well as the precision electroweak data. We first perform a scan to figure out the currently allowed parameter space of natural SUSY and then display the SUSY effects in $R_b$. We find that although the SUSY parameter space has been severely restrained by current experimental data, natural SUSY can still alter $R_b$ with a magnitude sizable enough to be observed at future $Z$-factories (ILC, CEPC, FCC-ee, Super $Z$-factory) which produce $10^9-10^{12}$ $Z$-bosons.

  17. First experimental results with the Current Limit Avoidance System at the JET tokamak

    Energy Technology Data Exchange (ETDEWEB)

    De Tommasi, G. [Associazione EURATOM-ENEA-CREATE, Università di Napoli Federico II, Via Claudio 21, 80125 Napoli (Italy); Galeani, S. [Dipartimento di Informatica, Sistemi e Produzione, Università di Roma, Tor Vergata, Rome (Italy); Jachmich, S. [Association EURATOM-Belgian State, Koninklijke Militaire School - Ecole Royale Militaire, B-1000 Brussels (Belgium); Joffrin, E. [IRFM-CEA, Centre de Cadarache, 13108 Saint-paul-lez-Durance (France); Lennholm, M. [EFDA Close Support Unit, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); European Commission, B-1049 Brussels (Belgium); Lomas, P.J. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Neto, A.C. [Associazione EURATOM-IST, Instituto de Plasmas e Fusao Nuclear, IST, 1049-001 Lisboa (Portugal); Maviglia, F. [Associazione EURATOM-ENEA-CREATE, Via Claudio 21, 80125 Napoli (Italy); McCullen, P. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Pironti, A. [Associazione EURATOM-ENEA-CREATE, Università di Napoli Federico II, Via Claudio 21, 80125 Napoli (Italy); Rimini, F.G. [Euratom-CCFE, Culham Science Centre, OX14 3DB Abingdon (United Kingdom); Sips, A.C.C. [European Commission, B-1049 Brussels (Belgium); Varano, G.; Vitelli, R. [Dipartimento di Informatica, Sistemi e Produzione, Università di Roma, Tor Vergata, Rome (Italy); Zaccarian, L. [CNRS, LAAS, 7 Avenue du Colonel Roche, F-31400 Toulouse (France); Universitè de Toulouse, LAAS, F-31400 Toulouse (France)

    2013-06-15

    The Current Limit Avoidance System (CLA) has been recently deployed at the JET tokamak to avoid current saturations in the poloidal field (PF) coils when the eXtreme Shape Controller is used to control the plasma shape. In order to cope with the current saturation limits, the CLA exploits the redundancy of the PF coils system to automatically obtain almost the same plasma shape using a different combination of currents in the PF coils. In the presence of disturbances it tries to avoid the current saturations by relaxing the constraints on the plasma shape control. The CLA system has been successfully implemented on the JET tokamak and fully commissioned in 2011. This paper presents the first experimental results achieved in 2011–2012 during the restart and the ITER-like wall campaigns at JET.

  18. Computational Design and Experimental Validation of New Thermal Barrier Systems

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Shengmin; Yang, Shizhong; Khosravi, Ebrahim

    2011-12-31

    This project (10/01/2010-9/30/2013), “Computational Design and Experimental Validation of New Thermal Barrier Systems”, originates from Louisiana State University (LSU) Mechanical Engineering Department and Southern University (SU) Department of Computer Science. This proposal will directly support the technical goals specified in DE-FOA-0000248, Topic Area 3: Turbine Materials, by addressing key technologies needed to enable the development of advanced turbines and turbine-based systems that will operate safely and efficiently using coal-derived synthesis gases. We will develop novel molecular dynamics method to improve the efficiency of simulation on novel TBC materials; we will perform high performance computing (HPC) on complex TBC structures to screen the most promising TBC compositions; we will perform material characterizations and oxidation/corrosion tests; and we will demonstrate our new Thermal barrier coating (TBC) systems experimentally under Integrated gasification combined cycle (IGCC) environments. The durability of the coating will be examined using the proposed High Temperature/High Pressure Durability Test Rig under real syngas product compositions.

  19. Simulation-based optimal Bayesian experimental design for nonlinear systems

    KAUST Repository

    Huan, Xun

    2013-01-01

    The optimal selection of experimental conditions is essential to maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. We propose a general mathematical framework and an algorithmic approach for optimal experimental design with nonlinear simulation-based models; in particular, we focus on finding sets of experiments that provide the most information about targeted sets of parameters.Our framework employs a Bayesian statistical setting, which provides a foundation for inference from noisy, indirect, and incomplete data, and a natural mechanism for incorporating heterogeneous sources of information. An objective function is constructed from information theoretic measures, reflecting expected information gain from proposed combinations of experiments. Polynomial chaos approximations and a two-stage Monte Carlo sampling method are used to evaluate the expected information gain. Stochastic approximation algorithms are then used to make optimization feasible in computationally intensive and high-dimensional settings. These algorithms are demonstrated on model problems and on nonlinear parameter inference problems arising in detailed combustion kinetics. © 2012 Elsevier Inc.

  20. A retrospective mathematical analysis of controlled release design and experimentation.

    Science.gov (United States)

    Rothstein, Sam N; Kay, Jennifer E; Schopfer, Francisco J; Freeman, Bruce A; Little, Steven R

    2012-11-01

    The development and performance evaluation of new biodegradable polymer controlled release formulations relies on successful interpretation and evaluation of in vitro release data. However, depending upon the extent of empirical characterization, release data may be open to more than one qualitative interpretation. In this work, a predictive model for release from degradable polymer matrices was applied to a number of published release data in order to extend the characterization of release behavior. Where possible, the model was also used to interpolate and extrapolate upon collected released data to clarify the overall duration of release and also kinetics of release between widely spaced data points. In each case examined, mathematical predictions of release coincide well with experimental results, offering a more definitive description of each formulation's performance than was previously available. This information may prove particularly helpful in the design of future studies, such as when calculating proper dosing levels or determining experimental end points in order to more comprehensively evaluate a controlled release system's performance.

  1. Quasi-experimental designs in practice-based research settings: design and implementation considerations.

    Science.gov (United States)

    Handley, Margaret A; Schillinger, Dean; Shiboski, Stephen

    2011-01-01

    Although randomized controlled trials are often a gold standard for determining intervention effects, in the area of practice-based research (PBR), there are many situations in which individual randomization is not possible. Alternative approaches to evaluating interventions have received increased attention, particularly those that can retain elements of randomization such that they can be considered "controlled" trials. Methodological design elements and practical implementation considerations for two quasi-experimental design approaches that have considerable promise in PBR settings--the stepped-wedge design, and a variant of this design, a wait-list cross-over design, are presented along with a case study from a recent PBR intervention for patients with diabetes. PBR-relevant design features include: creation of a cohort over time that collects control data but allows all participants (clusters or patients) to receive the intervention; staggered introduction of clusters; multiple data collection points; and one-way cross-over into the intervention arm. Practical considerations include: randomization versus stratification, training run in phases; and extended time period for overall study completion. Several design features of practice based research studies can be adapted to local circumstances yet retain elements to improve methodological rigor. Studies that utilize these methods, such as the stepped-wedge design and the wait-list cross-over design, can increase the evidence base for controlled studies conducted within the complex environment of PBR.

  2. MicroarrayDesigner: an online search tool and repository for near-optimal microarray experimental designs

    Directory of Open Access Journals (Sweden)

    Ferhatosmanoglu Nilgun

    2009-09-01

    Full Text Available Abstract Background Dual-channel microarray experiments are commonly employed for inference of differential gene expressions across varying organisms and experimental conditions. The design of dual-channel microarray experiments that can help minimize the errors in the resulting inferences has recently received increasing attention. However, a general and scalable search tool and a corresponding database of optimal designs were still missing. Description An efficient and scalable search method for finding near-optimal dual-channel microarray designs, based on a greedy hill-climbing optimization strategy, has been developed. It is empirically shown that this method can successfully and efficiently find near-optimal designs. Additionally, an improved interwoven loop design construction algorithm has been developed to provide an easily computable general class of near-optimal designs. Finally, in order to make the best results readily available to biologists, a continuously evolving catalog of near-optimal designs is provided. Conclusion A new search algorithm and database for near-optimal microarray designs have been developed. The search tool and the database are accessible via the World Wide Web at http://db.cse.ohio-state.edu/MicroarrayDesigner. Source code and binary distributions are available for academic use upon request.

  3. Diversified Approaches and Current Trends of Syllabus Design

    Institute of Scientific and Technical Information of China (English)

    靳亦诗

    2015-01-01

    <正>1.What is Syllabus Design According Nunan(2004),syllabus design is essentially concerned with the selection and grading of content,methodology with selecting and sequencing appropriate learning experience and evaluation with appraising learners and determining of the curriculum as a whole.Thus syllabus design has vital importance for the implication of the curriculum.

  4. Experimental Charging Behavior of Orion UltraFlex Array Designs

    Science.gov (United States)

    Golofaro, Joel T.; Vayner, Boris V.; Hillard, Grover B.

    2010-01-01

    The present ground based investigations give the first definitive look describing the charging behavior of Orion UltraFlex arrays in both the Low Earth Orbital (LEO) and geosynchronous (GEO) environments. Note the LEO charging environment also applies to the International Space Station (ISS). The GEO charging environment includes the bounding case for all lunar mission environments. The UltraFlex photovoltaic array technology is targeted to become the sole power system for life support and on-orbit power for the manned Orion Crew Exploration Vehicle (CEV). The purpose of the experimental tests is to gain an understanding of the complex charging behavior to answer some of the basic performance and survivability issues to ascertain if a single UltraFlex array design will be able to cope with the projected worst case LEO and GEO charging environments. Stage 1 LEO plasma testing revealed that all four arrays successfully passed arc threshold bias tests down to -240 V. Stage 2 GEO electron gun charging tests revealed that only the front side area of indium tin oxide coated array designs successfully passed the arc frequency tests

  5. Large-scale experimental design for decentralized SLAM

    Science.gov (United States)

    Cunningham, Alex; Dellaert, Frank

    2012-06-01

    This paper presents an analysis of large scale decentralized SLAM under a variety of experimental conditions to illustrate design trade-offs relevant to multi-robot mapping in challenging environments. As a part of work through the MAST CTA, the focus of these robot teams is on the use of small-scale robots with limited sensing, communication and computational resources. To evaluate mapping algorithms with large numbers (50+) of robots, we developed a simulation incorporating sensing of unlabeled landmarks, line-of-sight blocking obstacles, and communication modeling. Scenarios are randomly generated with variable models for sensing, communication, and robot behavior. The underlying Decentralized Data Fusion (DDF) algorithm in these experiments enables robots to construct a map of their surroundings by fusing local sensor measurements with condensed map information from neighboring robots. Each robot maintains a cache of previously collected condensed maps from neighboring robots, and actively distributes these maps throughout the network to ensure resilience to communication and node failures. We bound the size of the robot neighborhoods to control the growth of the size of neighborhood maps. We present the results of experiments conducted in these simulated scenarios under varying measurement models and conditions while measuring mapping performance. We discuss the trade-offs between mapping performance and scenario design, including robot teams separating and joining, multi-robot data association, exploration bounding, and neighborhood sizes.

  6. Tabletop Games: Platforms, Experimental Games and Design Recommendations

    Science.gov (United States)

    Haller, Michael; Forlines, Clifton; Koeffel, Christina; Leitner, Jakob; Shen, Chia

    While the last decade has seen massive improvements in not only the rendering quality, but also the overall performance of console and desktop video games, these improvements have not necessarily led to a greater population of video game players. In addition to continuing these improvements, the video game industry is also constantly searching for new ways to convert non-players into dedicated gamers. Despite the growing popularity of computer-based video games, people still love to play traditional board games, such as Risk, Monopoly, and Trivial Pursuit. Both video and board games have their strengths and weaknesses, and an intriguing conclusion is to merge both worlds. We believe that a tabletop form-factor provides an ideal interface for digital board games. The design and implementation of tabletop games will be influenced by the hardware platforms, form factors, sensing technologies, as well as input techniques and devices that are available and chosen. This chapter is divided into three major sections. In the first section, we describe the most recent tabletop hardware technologies that have been used by tabletop researchers and practitioners. In the second section, we discuss a set of experimental tabletop games. The third section presents ten evaluation heuristics for tabletop game design.

  7. Design, Simulation and Experimental Investigation of a Solar System Based on PV Panels and PVT Collectors

    Directory of Open Access Journals (Sweden)

    Annamaria Buonomano

    2016-06-01

    Full Text Available This paper presents numerical and experimental analyses aimed at evaluating the technical and economic feasibility of photovoltaic/thermal (PVT collectors. An experimental setup was purposely designed and constructed in order to compare the electrical performance of a PVT solar field with the one achieved by an identical solar field consisting of conventional photovoltaic (PV panels. The experimental analysis also aims at evaluating the potential advantages of PVT vs. PV in terms of enhancement of electrical efficiency and thermal energy production. The installed experimental set-up includes four flat polycrystalline silicon PV panels and four flat unglazed polycrystalline silicon PVT collectors. The total electrical power and area of the solar field are 2 kWe and 13 m2, respectively. The experimental set-up is currently installed at the company AV Project Ltd., located in Avellino (Italy. This study also analyzes the system from a numerical point of view, including a thermo-economic dynamic simulation model for the design and the assessment of energy performance and economic profitability of the solar systems consisting of glazed PVT and PV collectors. The experimental setup was modelled and partly simulated in TRNSYS environment. The simulation model was useful to analyze efficiencies and temperatures reached by such solar technologies, by taking into account the reference technology of PVTs (consisting of glazed collectors as well as to compare the numerical data obtained by dynamic simulations with the gathered experimental results for the PV technology. The numerical analysis shows that the PVT global efficiency is about 26%. Conversely, from the experimental point of view, the average thermal efficiency of PVT collectors is around 13% and the electrical efficiencies of both technologies are almost coincident and equal to 15%.

  8. Minimum quench power dissipation and current non-uniformity in international thermonuclear experimental reactor type NbTi cable-in-conduit conductor samples under direct current conditions

    Science.gov (United States)

    Rolando, G.; van Lanen, E. P. A.; Nijhuis, A.

    2012-05-01

    The level of current non-uniformity in NbTi cable-in-conduit conductors (CICCs) sections near the joints in combination with the magnetic field profile needs attention in view of proper joint design. The strand joule power and current distribution at quench under DC conditions of two samples of ITER poloidal field coil conductors, as tested in the SULTAN facility, and of the so called PFCI model coil insert, have been analyzed with the numerical cable model JackPot. The precise trajectories of all individual strands, joint design, cabling configuration, spatial distribution of the magnetic field, sample geometry, and experimentally determined interstrand resistance distributions have been taken into account. Although unable to predict the quench point due to the lack of a thermal-hydraulic routine, the model allows to assess the instantaneous strand power at quench and its local distribution in the cable once the quench conditions in terms of current and temperature are experimentally known. The analysis points out the relation of the above mentioned factors with the DC quench stability of both short samples and coils. The possible small scale and local electrical-thermal interactions were ignored in order to examine the relevance of such effects in the overall prediction of the CICC performance. The electromagnetic code shows an excellent quantitative predictive potential for CICC transport properties, excluding any freedom for matching the results. The influence of the local thermal effects in the modeling is identified as being marginal and far less than the generally accepted temperature margin for safe operation.

  9. Numerical and experimental design of coaxial shallow geothermal energy systems

    Science.gov (United States)

    Raghavan, Niranjan

    Geothermal Energy has emerged as one of the front runners in the energy race because of its performance efficiency, abundance and production competitiveness. Today, geothermal energy is used in many regions of the world as a sustainable solution for decreasing dependence on fossil fuels and reducing health hazards. However, projects related to geothermal energy have not received their deserved recognition due to lack of computational tools associated with them and economic misconceptions related to their installation and functioning. This research focuses on numerical and experimental system design analysis of vertical shallow geothermal energy systems. The driving force is the temperature difference between a finite depth beneath the earth and its surface stimulates continuous exchange of thermal energy from sub-surface to the surface (a geothermal gradient is set up). This heat gradient is captured by the circulating refrigerant and thus, tapping the geothermal energy from shallow depths. Traditionally, U-bend systems, which consist of two one-inch pipes with a U-bend connector at the bottom, have been widely used in geothermal applications. Alternative systems include coaxial pipes (pipe-in-pipe) that are the main focus of this research. It has been studied that coaxial pipes have significantly higher thermal performance characteristics than U-bend pipes, with comparative production and installation costs. This makes them a viable design upgrade to the traditional piping systems. Analytical and numerical heat transfer analysis of the coaxial system is carried out with the help of ABAQUS software. It is tested by varying independent parameters such as materials, soil conditions and effect of thermal contact conductance on heat transfer characteristics. With the above information, this research aims at formulating a preliminary theoretical design setup for an experimental study to quantify and compare the heat transfer characteristics of U-bend and coaxial

  10. EXPERIMENTAL INVESTIGATIONS ON DIFFUSION CHARACTERISTICS OF HIGH CONCENTRATION JETS IN ENVIRONMENTAL CURRENTS

    Institute of Scientific and Technical Information of China (English)

    张燕; 王道增; 樊靖郁

    2002-01-01

    By means of flow visualization and quantitative measurement, the diffusionpattern and concentration distribution characteristics of high concentration jets verticallydischarged into shallow moving waterbody were experimentally investigated in waterchannel. The interactions between the high concentration jets and environmental flowconditions were analysed, and the formulae of impinging point coordinate and transversespread angle are gained from data analysis. Experimental results indicate that the jets showcomplicated flow patterns and diffusion characteristics in near region, which are differentfrom common submerged jets, and spread downstream in the manner of density currents.

  11. Experimental Design of Electrocoagulation and Magnetic Technology for Enhancing Suspended Solids Removal from Synthetic Wastewater

    Directory of Open Access Journals (Sweden)

    Moh Faiqun Ni'am

    2014-10-01

    Full Text Available Design of experiments (DOE is one of the statistical method that is used as a tool to enhance and improve experimental quality. The changes to the variables of a process or system is supposed to give the optimal result (response and quite satisfactory. Experimental design can defined as a test or series of test series by varying the input variables (factors of a process that can known to cause changes in output (response. This paper presents the results of experimental design of wastewater treatment by electrocoagulation (EC technique. A combined magnet and electrocoagulation (EC technology were designed to increase settling velocity and to enhance suspended solid removal efficiencies from wastewater samples. In this experiment, a synthetic wastewater samples were prepared by mixing 700 mg of the milk powder in one litre of water and treated by using an acidic buffer solution. The monopolar iron (Fe plate anodes and cathodes were employed as electrodes. Direct current was varied in a range of between 0.5 and 1.1 A, and flowrate in a range of between 1.00 to 3.50 mL/s. One permanent magnets namely AlNiCo with a magnetic strength of 0.16T was used in this experiment. The results show that the magnetic field and the flowrate have major influences on suspended solids removal. The efficiency removals of suspended solids, turbidity and COD removal efficiencies at optimum conditions were found to be more than 85%, 95%, and 75%, respectively.

  12. Design Considerations for CMOS Current Mode Operational Amplifiers and Current Conveyors

    DEFF Research Database (Denmark)

    Bruun, Erik

    This dissertation is about CMOS current conveyors and current mode operational amplifiers (opamps). They are generic devices for continuous time signal processing in circuits and systems where signals are represented by currents.Substantial advancements are reported in the dissertation, both...... related to circuit implementations and system configurations and to an analysis of the fundamental limitations of the current mode technique.In the field of system configurations and circuit implementations different configurations of high gain current opamps are introduced and some of the first...... implementations of current mode opamps in CMOS technology are described. Also, current conveyor configurations with multiple outputs and flexible feedback connections from outputs to inputs are introduced. The dissertation includes several examples of circuit configurations ranging from simple class A and class...

  13. Experimental Research of Harmonic Spectrum of Currents at Traction Drive with PMSM

    Directory of Open Access Journals (Sweden)

    J. Novak

    2011-06-01

    Full Text Available The paper deals with the significant results of the experimental research of current harmonic spectrum of traction drive with permanent magnet synchronous motor. The experiments were done on a special workplace with a real traction drive for wheel vehicles. Current harmonic spectrum was analyzed by a specialized device on the base of central measuring station. The knowledge of current marked subharmonic components of stator winding is the most significant finding of experiments. The frequencies of these components are given by multiples of frequency of mechanical speeds. The subharmonic components also pass to input DC current of drive. This fact is important in particular from the point of view of legislative requirements to electromagnetic compatibility of drive with railway interlocking devices.

  14. The Current of Continuing Professional Development for Product Designers

    OpenAIRE

    山内, 勉; Yamauchi, Tsutomu

    2010-01-01

    Product Designers are required some skills and knowledge in the product development. Based on my professional career, I presumed three skills, they are, Technical skills, Conceptual skills and Human skills. In this study, I interviewed some Product Designers to make sure what skills are needed in the product development process. It emerged that Product Designers are expected to improve their Conceptual and Human skills besides Technical skills for playing a part at the upper and lower stage o...

  15. Evaluating the osseointegration of nanostructured titanium implants in animal models: Current experimental methods and perspectives (Review).

    Science.gov (United States)

    Babuska, Vaclav; Moztarzadeh, Omid; Kubikova, Tereza; Moztarzadeh, Amin; Hrusak, Daniel; Tonar, Zbynek

    2016-09-15

    The aim of this paper is to review the experimental methods currently being used to evaluate the osseointegration of nanostructured titanium implants using animal models. The material modifications are linked to the biocompatibility of various types of oral implants, such as laser-treated, acid-etched, plasma-coated, and sand-blasted surface modifications. The types of implants are reviewed according to their implantation site (endoosseous, subperiosteal, and transosseous implants). The animal species and target bones used in experimental implantology are carefully compared in terms of the ratio of compact to spongy bone. The surgical technique in animal experiments is briefly described, and all phases of the histological evaluation of osseointegration are described in detail, including harvesting tissue samples, processing undemineralized ground sections, and qualitative and quantitative histological assessment of the bone-implant interface. The results of histological staining methods used in implantology are illustrated and compared. A standardized and reproducible technique for stereological quantification of bone-implant contact is proposed and demonstrated. In conclusion, histological evaluation of the experimental osseointegration of dental implants requires careful selection of the experimental animals, bones, and implantation sites. It is also advisable to use larger animal models and older animals with a slower growth rate rather than small or growing experimental animals. Bones with a similar ratio of compact to spongy bone, such as the human maxilla and mandible, are preferred. A number of practical recommendations for the experimental procedures, harvesting of samples, tissue processing, and quantitative histological evaluations are provided.

  16. Statistical vs. stochastic experimental design: an experimental comparison on the example of protein refolding.

    Science.gov (United States)

    Anselment, Bernd; Schoemig, Veronika; Kesten, Christopher; Weuster-Botz, Dirk

    2012-01-01

    Optimization of experimental problems is a challenging task in both engineering and science. In principle, two different design of experiments (DOE) strategies exist: statistical and stochastic methods. Both aim to efficiently and precisely identify optimal solutions inside the problem-specific search space. Here, we evaluate and compare both strategies on the same experimental problem, the optimization of the refolding conditions of the lipase from Thermomyces lanuginosus with 26 variables under study. Protein refolding is one of the main bottlenecks in the process development for recombinant proteins. Despite intensive effort, the prediction of refolding from sequence information alone is still not applicable today. Instead, suitable refolding conditions are typically derived empirically in large screening experiments. Thus, protein refolding should constitute a good performance test for DOE strategies. We compared an iterative stochastic optimization applying a genetic algorithm and a standard statistical design consisting of a D-optimal screening step followed by an optimization via response surface methodology. Our results revealed that only the stochastic optimization was able to identify optimal refolding conditions (~1.400 U g(-1) refolded activity), which were 3.4-fold higher than the standard. Additionally, the stochastic optimization proved quite robust, as three independent optimizations performed similar. In contrast, the statistical DOE resulted in a suboptimal solution and failed to identify comparable activities. Interactions between process variables proved to be pivotal for this optimization. Hence, the linear screening model was not able to identify the most important process variables correctly. Thereby, this study highlighted the limits of the classic two-step statistical DOE.

  17. Research and design of a novel current mode charge pump

    Science.gov (United States)

    Xianrui, Li; Xinquan, Lai; Yushan, Li; Qiang, Ye

    2009-10-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  18. Research and design of a novel current mode charge pump

    Energy Technology Data Exchange (ETDEWEB)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang, E-mail: lixianrui4213@126.co [Research Institute of Design Circuit, Xidian University, Xi' an 710071 (China)

    2009-10-15

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transconductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice simulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 {mu}s, and the load current jumps from 400 to 800 mA.

  19. Research and design of a novel current mode charge pump

    Institute of Scientific and Technical Information of China (English)

    Li Xianrui; Lai Xinquan; Li Yushan; Ye Qiang

    2009-01-01

    To meet the demands for a number of LEDs, a novel charge pump circuit with current mode control is proposed. Regulation is achieved by operating the current mirrors and the output current of the operational transcon ductance amplifier. In the steady state, the input current from power voltage retains constant, so reducing the noise induced on the input voltage source and improving the output voltage ripple. The charge pump small-signal model is used to describe the device's dynamic behavior and stability. Analytical predictions were verified by Hspice sim ulation and testing. Load driving is up to 800 mA with a power voltage of 3.6 V, and the output voltage ripple is less than 45 mV. The output response time is less than 8 μs, and the load current jumps from 400 to 800 mA.

  20. Experimental manifestation of the breakpoint region in the current-voltage characteristics of intrinsic Josephson junctions

    Science.gov (United States)

    Irie, A.; Shukrinov, Yu. M.; Oya, G.

    2008-10-01

    The experimental evidence of the breakpoint on the current-voltage characteristics (IVCs) of the stacks of intrinsic Josephson junctions (IJJs) is presented. The influence of the capacitive coupling on the IVCs of Bi2Sr2CaCu2Oy IJJs has been investigated. At 4.2K, clear breakpoint region is observed on the branches in the IVCs. It is found that due to the coupling between junctions, the hysteresis observed on the IVC is small compared to that expected from the McCumber parameter. Measurements agree well with the results predicted by the capacitively coupled Josephson junction model including the diffusion current.

  1. Experimental and Numerical Study of Wave-Induced Long-Shore Currents on A Mild Slope Beach

    Institute of Scientific and Technical Information of China (English)

    SUN Tao; TAO Jian-hua

    2005-01-01

    The long-shore current distribution on a mild slope beach is studied by combining the numerical model and the physical experiment. The experiments of long-shore currents under the action of regular and irregular waves are conducted on mild beaches with different slopes in a wave basin. A numerical model is established, which includes a wave propagation model, a wave breaking model and a long-shore current model. The validity of the numerical model is proved by the comparison of its results with the results of the experimental model. It is concluded that the wave-induced long-shore current is influenced significantly by the incident wave height, the wave angle and the beach slope. Its application to the Bohai Bay indicates that the wave-induced currents have the same order of magnitude as the tide currents in the near-shore zone of mill slope beach. In the design of wastewater outfall locations on a mild-slope beach with shallow water of the Bohai Bay, the position of the outfall should be 10 km away from the shoreline, which is outside of the surf-zone.

  2. Design Considerations for CMOS Current Mode Operational Amplifiers and Current Conveyors

    DEFF Research Database (Denmark)

    Bruun, Erik

    This dissertation is about CMOS current conveyors and current mode operational amplifiers (opamps). They are generic devices for continuous time signal processing in circuits and systems where signals are represented by currents.Substantial advancements are reported in the dissertation, both...... implementations of current mode opamps in CMOS technology are described. Also, current conveyor configurations with multiple outputs and flexible feedback connections from outputs to inputs are introduced. The dissertation includes several examples of circuit configurations ranging from simple class A and class...... AB conveyor implementations to implementations based on purely digital circuit structures and on more complex analog subsystems such as a voltage mode opamp with feedback to provide a voltage follower action. An important by-product of the investigation of current mode structures is the definition...

  3. Starting Over: Current Issues in Online Catalog User Interface Design.

    Science.gov (United States)

    Crawford, Walt

    1992-01-01

    Discussion of online catalogs focuses on issues in interface design. Issues addressed include understanding the user base; common user access (CUA) with personal computers; common command language (CCL); hyperlinks; screen design issues; differences from card catalogs; indexes; graphic user interfaces (GUIs); color; online help; and remote users.…

  4. A comparison of methods currently used in inclusive design.

    Science.gov (United States)

    Goodman-Deane, Joy; Ward, James; Hosking, Ian; Clarkson, P John

    2014-07-01

    Inclusive design has unique challenges because it aims to improve usability for a wide range of users. This typically includes people with lower levels of ability, as well as mainstream users. This paper examines the effectiveness of two methods that are used in inclusive design: user trials and exclusion calculations (an inclusive design inspection method). A study examined three autoinjectors using both methods (n=30 for the user trials). The usability issues identified by each method are compared and the effectiveness of the methods is discussed. The study found that each method identified different kinds of issues, all of which are important for inclusive design. We therefore conclude that a combination of methods should be used in inclusive design rather than relying on a single method. Recommendations are also given for how the individual methods can be used more effectively in this context.

  5. Design review of the Brazilian Experimental Solar Telescope

    Science.gov (United States)

    Dal Lago, A.; Vieira, L. E. A.; Albuquerque, B.; Castilho, B.; Guarnieri, F. L.; Cardoso, F. R.; Guerrero, G.; Rodríguez, J. M.; Santos, J.; Costa, J. E. R.; Palacios, J.; da Silva, L.; Alves, L. R.; Costa, L. L.; Sampaio, M.; Dias Silveira, M. V.; Domingues, M. O.; Rockenbach, M.; Aquino, M. C. O.; Soares, M. C. R.; Barbosa, M. J.; Mendes, O., Jr.; Jauer, P. R.; Branco, R.; Dallaqua, R.; Stekel, T. R. C.; Pinto, T. S. N.; Menconi, V. E.; Souza, V. M. C. E. S.; Gonzalez, W.; Rigozo, N.

    2015-12-01

    The Brazilian's National Institute for Space Research (INPE), in collaboration with the Engineering School of Lorena/University of São Paulo (EEL/USP), the Federal University of Minas Gerais (UFMG), and the Brazilian's National Laboratory for Astrophysics (LNA), is developing a solar vector magnetograph and visible-light imager to study solar processes through observations of the solar surface magnetic field. The Brazilian Experimental Solar Telescope is designed to obtain full disk magnetic field and line-of-sight velocity observations in the photosphere. Here we discuss the system requirements and the first design review of the instrument. The instrument is composed by a Ritchey-Chrétien telescope with a 500 mm aperture and 4000 mm focal length. LCD polarization modulators will be employed for the polarization analysis and a tuning Fabry-Perot filter for the wavelength scanning near the Fe II 630.25 nm line. Two large field-of-view, high-resolution 5.5 megapixel sCMOS cameras will be employed as sensors. Additionally, we describe the project management and system engineering approaches employed in this project. As the magnetic field anchored at the solar surface produces most of the structures and energetic events in the upper solar atmosphere and significantly influences the heliosphere, the development of this instrument plays an important role in advancing scientific knowledge in this field. In particular, the Brazilian's Space Weather program will benefit most from the development of this technology. We expect that this project will be the starting point to establish a strong research program on Solar Physics in Brazil. Our main aim is to progressively acquire the know-how to build state-of-art solar vector magnetograph and visible-light imagers for space-based platforms.

  6. Experimentally determined mechanical properties of, and models for, the periodontal ligament: critical review of current literature.

    Science.gov (United States)

    Fill, Ted S; Carey, Jason P; Toogood, Roger W; Major, Paul W

    2011-01-01

    Introduction. This review is intended to highlight and discuss discrepancies in the literature of the periodontal ligament's (PDL) mechanical properties and the various experimental approaches used to measure them. Methods. Searches were performed on biomechanical and orthodontic publications (in databases: Compendex, EMBASE, MEDLINE, PubMed, ScienceDirect, and Scopus). Results. The review revealed that significant variations exist, some on the order of six orders of magnitude, in the PDL's elastic constants and mechanical properties. Possible explanations may be attributable to different experimental approaches and assumptions. Conclusions. The discrepancies highlight the need for further research into PDL properties under various clinical and experimental loading conditions. Better understanding of the PDL's biomechanical behavior under physiologic and traumatic loading conditions might enhance the understanding of the PDL's biologic reaction in health and disease. Providing a greater insight into the response of the PDL would be instrumental to orthodontists and engineers for designing more predictable, and therefore more efficacious, orthodontic appliances.

  7. Overview and Current Status of Analyses of Potential LEU Design Concepts for TREAT

    Energy Technology Data Exchange (ETDEWEB)

    Connaway, H. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Kontogeorgakos, D. C. [Argonne National Lab. (ANL), Argonne, IL (United States); Papadias, D. D. [Argonne National Lab. (ANL), Argonne, IL (United States); Wright, A. E. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-10-01

    Neutronic and thermal-hydraulic analyses have been performed to evaluate the performance of different low-enriched uranium (LEU) fuel design concepts for the conversion of the Transient Reactor Test Facility (TREAT) from its current high-enriched uranium (HEU) fuel. TREAT is an experimental reactor developed to generate high neutron flux transients for the testing of nuclear fuels. The goal of this work was to identify an LEU design which can maintain the performance of the existing HEU core while continuing to operate safely. A wide variety of design options were considered, with a focus on minimizing peak fuel temperatures and optimizing the power coupling between the TREAT core and test samples. Designs were also evaluated to ensure that they provide sufficient reactivity and shutdown margin for each control rod bank. Analyses were performed using the core loading and experiment configuration of historic M8 Power Calibration experiments (M8CAL). The Monte Carlo code MCNP was utilized for steady-state analyses, and transient calculations were performed with the point kinetics code TREKIN. Thermal analyses were performed with the COMSOL multi-physics code. Using the results of this study, a new LEU Baseline design concept is being established, which will be evaluated in detail in a future report.

  8. Optimal experimental design with the sigma point method.

    Science.gov (United States)

    Schenkendorf, R; Kremling, A; Mangold, M

    2009-01-01

    Using mathematical models for a quantitative description of dynamical systems requires the identification of uncertain parameters by minimising the difference between simulation and measurement. Owing to the measurement noise also, the estimated parameters possess an uncertainty expressed by their variances. To obtain highly predictive models, very precise parameters are needed. The optimal experimental design (OED) as a numerical optimisation method is used to reduce the parameter uncertainty by minimising the parameter variances iteratively. A frequently applied method to define a cost function for OED is based on the inverse of the Fisher information matrix. The application of this traditional method has at least two shortcomings for models that are nonlinear in their parameters: (i) it gives only a lower bound of the parameter variances and (ii) the bias of the estimator is neglected. Here, the authors show that by applying the sigma point (SP) method a better approximation of characteristic values of the parameter statistics can be obtained, which has a direct benefit on OED. An additional advantage of the SP method is that it can also be used to investigate the influence of the parameter uncertainties on the simulation results. The SP method is demonstrated for the example of a widely used biological model.

  9. Sparsely Sampling the Sky: A Bayesian Experimental Design Approach

    CERN Document Server

    Paykari, P

    2012-01-01

    The next generation of galaxy surveys will observe millions of galaxies over large volumes of the universe. These surveys are expensive both in time and cost, raising questions regarding the optimal investment of this time and money. In this work we investigate criteria for selecting amongst observing strategies for constraining the galaxy power spectrum and a set of cosmological parameters. Depending on the parameters of interest, it may be more efficient to observe a larger, but sparsely sampled, area of sky instead of a smaller contiguous area. In this work, by making use of the principles of Bayesian Experimental Design, we will investigate the advantages and disadvantages of the sparse sampling of the sky and discuss the circumstances in which a sparse survey is indeed the most efficient strategy. For the Dark Energy Survey (DES), we find that by sparsely observing the same area in a smaller amount of time, we only increase the errors on the parameters by a maximum of 0.45%. Conversely, investing the sam...

  10. Computational and experimental studies of laser cutting of the current collectors for lithium-ion batteries

    Science.gov (United States)

    Lee, Dongkyoung; Patwa, Rahul; Herfurth, Hans; Mazumder, Jyotirmoy

    2012-07-01

    Sizing electrodes is an important step during Lithium-ion battery manufacturing processes since poor cut edge affects battery performance significantly and sometime leads to fire hazard. Mechanical cutting could result in a poor cut quality with defects. The cutting quality can be improved by using a laser, due to its high energy concentration, fast processing time, small heat-affected zone, and high precision. The cutting quality is highly influenced by operating parameters such as laser power and scanning speed. Thus, we studied a numerical simulation to provide a guideline for achieving clear edge quality. In order to simulate electrodes laser cutting for Lithium-Ion batteries, understanding the behavior of current collectors is crucial. This study focuses on current collectors, such as pure copper and aluminium. Numerical studies utilized a 3D self-consistent mathematical model for laser-material interaction. Observations of penetration time, depth, and threshold during laser cutting processes of current collectors are described. The model is validated experimentally by cutting current collectors and single side-coated electrodes with a single mode fiber laser. The copper laser cutting is laser intensity and interaction time dependent process. The aluminium laser cutting depends more on laser intensity than the interaction time. Numerical and experimental results show good agreement.

  11. Principle and experimental investigation of current-driven negative-inductance superconducting quantum interference device

    Science.gov (United States)

    Li, Hao; Liu, Jianshe; Zhang, Yingshan; Cai, Han; Li, Gang; Liu, Qichun; Han, Siyuan; Chen, Wei

    2017-03-01

    A negative-inductance superconducting quantum interference device (nSQUID) is an adiabatic superconducting logic device with high energy efficiency, and therefore a promising building block for large-scale low-power superconducting computing. However, the principle of the nSQUID is not that straightforward and an nSQUID driven by voltage is vulnerable to common mode noise. We investigate a single nSQUID driven by current instead of voltage, and clarify the principle of the adiabatic transition of the current-driven nSQUID between different states. The basic logic operations of the current-driven nSQUID with proper parameters are simulated by WRspice. The corresponding circuit is fabricated with a 100 A cm‑2 Nb-based lift-off process, and the experimental results at low temperature confirm the basic logic operations as a gated buffer.

  12. Experimental study of the velocity of density currents in convergent and divergent channels

    Institute of Scientific and Technical Information of China (English)

    Hasan Torabi POUDEH; Samad EMAMGHOLIZADEH; Manoocher Fathi-MOGHADAM

    2014-01-01

    The head velocity of the density current in the convergent and divergent channel is a key parameter for evaluating the extent to which suspended material travels, and for determining the type and distribution of sediment in the water body. This study experimentally evaluated the effects of the reach degree of convergence and divergence on the head velocity of the density current. Experiments were conducted in the flume with 6.0 m long, 0.72 m width and 0.6 m height. The head velocity was measured at three convergent degrees (-8o;-12o;-26o), at three divergent degrees (8o; 12o; 26o) and two slopes (0.009, 0.016) for various discharges. The measured head velocity of the density current is compared with the head velocity of the density current in the constant cross section channel. Based on non-dimensional and statistical analysis, relations as linear multiple regression are offered for predicting head velocity of the density current in the convergent, divergent and constant cross section channel. Also the results of this research show that for the same slope and discharge, the head velocity of the density current in the convergent and divergent channel are greater and less than the head velocity of the constant cross section, respectively.

  13. [Experimental design and data handling in food microbiology].

    Science.gov (United States)

    Carbonell, E A

    1993-02-01

    A discussion on the problems associated with designing experiments in Food Microbiology research is presented. After defining what is meant by Design of an Experiment, a series of questions are raised that, once answered, will help in properly designing the experiment. It is emphasized the chain research-design-model-analysis-design and the danger in blindly using well-known designs and canned programs.

  14. Stemless shoulder arthroplasty-current results and designs.

    Science.gov (United States)

    Churchill, R Sean; Athwal, George S

    2016-03-01

    Stemless shoulder arthroplasty was originally introduced in 2004 by a single manufacturer. Now, over a decade later, numerous designs are available outside the USA, but as yet, only one implant has been cleared by the Food and Drug Administration (FDA) and is available for use within the USA. Often referred to as "canal sparing," these implants are designed for metaphyseal fixation to minimize humeral bone removal, avoid intraoperative and postoperative humeral fracture complications, and to decrease morbidity associated with revision operations. Recently, the second generation of stemless arthroplasty, a convertible implant allowing use in either anatomic or reverse arthroplasty configuration, was released for use outside the USA. This paper will review the available designs, reported results, and raise potential concerns for this emerging technology.

  15. An efficient approach to bioconversion kinetic model generation based on automated microscale experimentation integrated with model driven experimental design

    DEFF Research Database (Denmark)

    Chen, B. H.; Micheletti, M.; Baganz, F.;

    2009-01-01

    design. It incorporates a model driven approach to the experimental design that minimises the number of experiments to be performed, while still generating accurate values of kinetic parameters. The approach has been illustrated with the transketolase mediated asymmetric synthesis of L...... experimental design.]it comparison with conventional methodology, the modelling approach enabled a nearly 4-fold decrease in the number of experiments while the microwell experimentation enabled a 45-fold decrease in material requirements and a significant increase in experimental throughput. The approach......Reliable models of enzyme kinetics are required for the effective design of bioconversion processes. Kinetic expressions of the enzyme-catalysed reaction rate however, are frequently complex and establishing accurate values of kinetic parameters normally requires a large number of experiments...

  16. Design of a microscopic electrical impedance tomography system using two current injections.

    Science.gov (United States)

    Liu, Qin; Oh, Tong In; Wi, Hun; Lee, Eun Jung; Seo, Jin Keun; Woo, Eung Je

    2011-09-01

    We describe a novel design of a microscopic electrical impedance tomography (micro-EIT) system for long-term noninvasive monitoring of cell or tissue cultures. The core of the micro-EIT system is a sample container including two pairs of current-injection electrodes and 360 voltage-sensing electrodes. In designing the container, we took advantage of a hexagonal structure with fixed dimensions and electrode configuration. This eliminated technical difficulties related to the unknown irregular boundary geometry of an imaging object in conventional medical EIT. Attaching a pair of large current-injection electrodes fully covering the left and right sides of the hexagonal container, we generated uniform parallel current density inside the container filled with saline. The 360 voltage-sensing electrodes were placed on the front, bottom and back sides of the hexagonal container in three sets of 8 × 15 arrays with equal gaps between them. We measured voltage differences between all neighboring pairs along the direction of the parallel current pathway. For the homogeneous container, all measured voltages must be the same since the voltage changes linearly along that direction. Any anomaly in the container perturbed the current pathways and therefore equipotential lines to produce different differential voltage data. For conductivity image reconstructions, we adopted a lately developed image reconstruction algorithm for this electrode configuration to first produce projected conductivity images on the front, bottom and back sides. Using a backprojection method, we reconstructed three-dimensional conductivity images from those projection images. To improve the image quality and also to meet the mathematical requirement on the uniqueness of a reconstructed image, we used a second pair of thin and long current-injection electrodes located at the middle of the front and back sides. This paper describes the design and construction of such a micro-EIT system with experimental

  17. Experimental design of a fuzzy controller for improving power factor of boost rectifier

    Science.gov (United States)

    Kessal, Abdelhalim; Rahmani, Lazhar; Gaubert, Jean-Paul; Mostefai, Mohammed

    2012-12-01

    This article presents the design and the implementation of dSPACE DS1104 controller board-based PI and fuzzy logic peak current-mode controllers in the voltage loop and two controllers in the current loop based first on a standard fixed hysteresis band control, followed by a variable hysteresis band control to achieve constant switching frequency for a single-phase active power factor corrector in the continuous conduction mode. All these controllers have been verified via simulation in Simulink and a real-time implementation is performed on an experimental test bench utilising a rapid prototyping tool. The controllers are experimentally compared for steady-state performance and transient response. It is shown that the PI and fuzzy logic controllers give a superior steady-state performance, whereas the fuzzy logic inference based controller can achieve better dynamic response than its PI counterpart under large load disturbance and plant uncertainties. Furthermore, the variable hysteresis band control in the current loop gives a low total harmonic distortion of the input current compared to a standard fixed hysteresis band control.

  18. Selecting appropriate animal models and experimental designs for endocrine disruptor research and testing studies.

    Science.gov (United States)

    Stokes, William S

    2004-01-01

    Evidence that chemicals in the environment may cause developmental and reproductive abnormalities in fish and wildlife by disrupting normal endocrine functions has increased concern about potential adverse human health effects from such chemicals. US laws have now been enacted that require the US Environmental Protection Agency (EPA) to develop and validate a screening program to identify chemicals in food and water with potential endocrine-disrupting activity. EPA subsequently proposed an Endocrine Disruptor Screening Program that uses in vitro and in vivo test systems to identify chemicals that may adversely affect humans and ecologically important animal species. However, the endocrine system can be readily modulated by many experimental factors, including diet and the genetic background of the selected animal strain or stock. It is therefore desirable to minimize or avoid factors that cause or contribute to experimental variation in endocrine disruptor research and testing studies. Standard laboratory animal diets contain high and variable levels of phytoestrogens, which can modulate physiologic and behavioral responses similar to both endogenous estrogen as well as exogenous estrogenic chemicals. Other studies have determined that some commonly used outbred mice and rats are less responsive to estrogenic substances than certain inbred mouse and rat strains for various estrogen-sensitive endpoints. It is therefore critical to select appropriate biological models and diets for endocrine disruptor studies that provide optimal sensitivity and specificity to accomplish the research or testing objectives. An introduction is provided to 11 other papers in this issue that review these and other important laboratory animal experimental design considerations in greater detail, and that review laboratory animal and in vitro models currently being used or evaluated for endocrine disruptor research and testing. Selection of appropriate animal models and experimental design

  19. Current Developments in Language Curriculum Design: An Australian Perspective.

    Science.gov (United States)

    Burton, Jill

    1998-01-01

    A review of literature on second-language curriculum design in Australia outlines some general trends in communicative language teaching theory and needs-based language curriculum planning, task-based learning, and recent cultural, social, and literacy perspectives on curriculum, and then examines specific initiatives to reform curricula, to…

  20. Concept learning by direct current design challenges in secondary education

    NARCIS (Netherlands)

    Van Breukelen, D.H.J.; De Vries, M.J.; Schure, F.A.

    2016-01-01

    This paper presents a mixed methods study in which 77 students and 3 teachers took part, that investigated the practice of Learning by Design (LBD). The study is part of a series of studies, funded by the Netherlands Organisation for Scientific Research, that aims to improve student learning, teachi

  1. Concept Learning by Direct Current Design Challenges in Secondary Education

    Science.gov (United States)

    van Breukelen, Dave H. J.; de Vries, Marc J.; Schure, Frank A.

    2017-01-01

    This paper presents a mixed methods study in which 77 students and 3 teachers took part, that investigated the practice of Learning by Design (LBD). The study is part of a series of studies, funded by the Netherlands Organisation for Scientific Research, that aims to improve student learning, teaching skills and teacher training. LBD uses the…

  2. Experimental Design on Laminated Veneer Lumber Fiber Composite: Surface Enhancement

    Science.gov (United States)

    Meekum, U.; Mingmongkol, Y.

    2010-06-01

    Thick laminate veneer lumber(LVL) fibre reinforced composites were constructed from the alternated perpendicularly arrayed of peeled rubber woods. Glass woven was laid in between the layers. Native golden teak veneers were used as faces. In house formulae epoxy was employed as wood adhesive. The hand lay-up laminate was cured at 150° C for 45 mins. The cut specimen was post cured at 80° C for at least 5 hours. The 2k factorial design of experimental(DOE) was used to verify the parameters. Three parameters by mean of silane content in epoxy formulation(A), smoke treatment of rubber wood surface(B) and anti-termite application(C) on the wood surface were analysed. Both low and high levels were further subcategorised into 2 sub-levels. Flexural properties were the main respond obtained. ANOVA analysis of the Pareto chart was engaged. The main effect plot was also testified. The results showed that the interaction between silane quantity and termite treatment is negative effect at high level(AC+). Vice versa, the interaction between silane and smoke treatment was positive significant effect at high level(AB+). According to this research work, the optimal setting to improve the surface adhesion and hence flexural properties enhancement were high level of silane quantity, 15% by weight, high level of smoked wood layers, 8 out of 14 layers, and low anti termite applied wood. The further testes also revealed that the LVL composite had superior properties that the solid woods but slightly inferior in flexibility. The screw withdrawn strength of LVL showed the higher figure than solid wood. It is also better resistance to moisture and termite attack than the rubber wood.

  3. Optimization of model parameters and experimental designs with the Optimal Experimental Design Toolbox (v1.0) exemplified by sedimentation in salt marshes

    Science.gov (United States)

    Reimer, J.; Schuerch, M.; Slawig, T.

    2015-03-01

    The geosciences are a highly suitable field of application for optimizing model parameters and experimental designs especially because many data are collected. In this paper, the weighted least squares estimator for optimizing model parameters is presented together with its asymptotic properties. A popular approach to optimize experimental designs called local optimal experimental designs is described together with a lesser known approach which takes into account the potential nonlinearity of the model parameters. These two approaches have been combined with two methods to solve their underlying discrete optimization problem. All presented methods were implemented in an open-source MATLAB toolbox called the Optimal Experimental Design Toolbox whose structure and application is described. In numerical experiments, the model parameters and experimental design were optimized using this toolbox. Two existing models for sediment concentration in seawater and sediment accretion on salt marshes of different complexity served as an application example. The advantages and disadvantages of these approaches were compared based on these models. Thanks to optimized experimental designs, the parameters of these models could be determined very accurately with significantly fewer measurements compared to unoptimized experimental designs. The chosen optimization approach played a minor role for the accuracy; therefore, the approach with the least computational effort is recommended.

  4. City Connects: Building an Argument for Effects on Student Achievement with a Quasi-Experimental Design

    Science.gov (United States)

    Walsh, Mary; Raczek, Anastasia; Sibley, Erin; Lee-St. John, Terrence; An, Chen; Akbayin, Bercem; Dearing, Eric; Foley, Claire

    2015-01-01

    While randomized experimental designs are the gold standard in education research concerned with causal inference, non-experimental designs are ubiquitous. For researchers who work with non-experimental data and are no less concerned for causal inference, the major problem is potential omitted variable bias. In this presentation, the authors…

  5. 14 CFR 437.85 - Allowable design changes; modification of an experimental permit.

    Science.gov (United States)

    2010-01-01

    ... Conditions of an Experimental Permit § 437.85 Allowable design changes; modification of an experimental... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Allowable design changes; modification of an experimental permit. 437.85 Section 437.85 Aeronautics and Space COMMERCIAL SPACE...

  6. Numerical simulation and experimental validation of a direct current air corona discharge under atmospheric pressure

    Institute of Scientific and Technical Information of China (English)

    Liu Xing-Hua; He Wei; Yang Fan; Wang Hong-Yu; Liao Rui-Jin; Xiao Han-Guang

    2012-01-01

    Air corona discharge is one of the critical problems associated with high-voltage equipment.Investigating the corona mechanism plays a key role in enhancing the electrical insulation performance.An improved self-consistent multi-component two-dimensional plasma hybrid model is presented for the simulation of a direct current atmospheric pressure corona discharge in air.The model is based on plasma hydrodynamic and chemical models,and includes 12 species and 26 reactions.In addition,the photoionization effect is introduced into the model.The simulation on a bar-plate electrode configuration with an inter-electrode gap of 5.0 mm is carried out.The discharge voltage-current characteristics and the current density distribution predicted by the hybrid model agree with the experimental measurements.In addition,the dynamics of volume charged species generation,discharge current waveform,current density distribution at an electrode,charge density,electron temperature,and electric field variations are investigated in detail based on the model.The results indicate that the model can contribute valuable insights into the physics of an air plasma discharge.

  7. Design Rework Prediction in Concurrent Design Environment: Current Trends and Future Research Directions

    OpenAIRE

    Arundachawat, Panumas; Roy, Rajkumar; Al-Ashaab, Ahmed; Shehab, Essam

    2009-01-01

    This paper aims to present state-of-the-art and formulate future research areas on design rework in concurrent design environment. Related literatures are analysed to extract the key factors which impact design rework. Design rework occurs due to changes from upstream design activities and/or by feedbacks from downstream design activities. Design rework is considered as negative iteration; therefore, value in design activities will be increased if design rework is reduced. Set-bas...

  8. Surveying clinicians by web: current issues in design and administration.

    Science.gov (United States)

    Dykema, Jennifer; Jones, Nathan R; Piché, Tara; Stevenson, John

    2013-09-01

    The versatility, speed, and reduced costs with which web surveys can be conducted with clinicians are often offset by low response rates. Drawing on best practices and general recommendations in the literature, we provide an evidence-based overview of methods for conducting online surveys with providers. We highlight important advantages and disadvantages of conducting provider surveys online and include a review of differences in response rates between web and mail surveys of clinicians. When administered online, design-based features affect rates of survey participation and data quality. We examine features likely to have an impact including sample frames, incentives, contacts (type, timing, and content), mixed-mode approaches, and questionnaire length. We make several recommendations regarding optimal web-based designs, but more empirical research is needed, particularly with regard to identifying which combinations of incentive and contact approaches yield the highest response rates and are the most cost-effective.

  9. Design, modification and test of the conduction cooled high-current current leads for the superconducting magnet

    Science.gov (United States)

    Peng, Quanling; Cheng, Da; Xu, Fengyu; Yang, Xiangchen; Wang, Ting; Wei, Xiaotao

    2017-09-01

    Conduction cooled current leads, which bring the current from the room temperature terminal down to the cryogenic environment, were used in common recently in large scale superconducting accelerators for its low cost, sample design and low heat load. In practice, the current lead is designed contained in a stainless steel tube. The heat load can be incepted in steps by thermal anchors, where one end is attached to the stainless steel tube, while the other end is connected with the cold shield of the cryomodule. Since the limitation of the welding technique, a thicker stainless steel tube needs to be used, and hence the thermal anchors cannot provide enough pressure to deform the tube enough to be in direct contact with the current lead, which may lead to temperature instability and bring extra heat load to the cryogenic system. An excellent option of epoxy filled current lead can realize the fully contact and reduce the heat load effectively. This paper will present the process of the current lead design, optimization, numerical simulation and cryogenic test, the test results show that the current lead can keep in a stable operation and low heat load.

  10. Computer-Aided Design of a Direct Current Electromagnet

    Directory of Open Access Journals (Sweden)

    Iancu Tătucu

    2009-10-01

    Full Text Available The paper presents the mathematical model and the simulation of a direct current electromagnet used for the transport of the steel ingots. For the simulation of any device one must dispose of a mathematical model, able to describe as accurately as possible the phenomena that take place. As the processes occurred in the case of an electromagnet are of an electromagnetic nature, one used the model of the electromagnetic potentials, and the simulation was performed with the help of the specialised software ANSYS.

  11. Experimental manifestation of the breakpoint region in the current-voltage characteristics of intrinsic Josephson junctions

    OpenAIRE

    Irie, A.; Shukrinov, Yu M.; Oya, G.

    2008-01-01

    The experimental evidence of the breakpoint on the current-voltage characteristics (IVCs) of the stacks of intrinsic Josephson junctions (IJJs) is presented. The influence of the capacitive coupling on the IVCs of Bi$_2$Sr$_2$CaCu$_2$O$_y$ IJJs has been investigated. At 4.2 K, clear breakpoint region is observed on the branches in the IVCs. It is found that the hysteresis observed on the IVC is suppressed due to the coupling compared with that expected from the McCumber parameter. Measurement...

  12. Thermal Dissipation Modelling and Design of ITER PF Converter Alternating Current Busbar

    Science.gov (United States)

    Guo, Bin; Song, Zhiquan; Fu, Peng; Jiang, Li; Li, Jinchao; Wang, Min; Dong, Lin

    2016-10-01

    Because the larger metallic surrounds are heated by the eddy current, which is generated by the AC current flowing through the AC busbar in the International Thermonuclear Experimental Reactor (ITER) poloidal field (PF) converter system, shielding of the AC busbar is required to decrease the temperature rise of the surrounds to satisfy the design requirement. Three special types of AC busbar with natural cooling, air cooling and water cooling busbar structure have been proposed and investigated in this paper. For each cooling scheme, a 3D finite model based on the proposed structure has been developed to perform the electromagnetic and thermal analysis to predict their operation behavior. Comparing the analysis results of the three different cooling patterns, water cooling has more advantages than the other patterns and it is selected to be the thermal dissipation pattern for the AC busbar of ITER PF converter unit. The approach to qualify the suitable cooling scheme in this paper can be provided as a reference on the thermal dissipation design of AC busbar in the converter system. supported by National Natural Science Foundation of China (No. 51407179)

  13. Designing a highly sensitive Eddy current sensor for evaluating damage on thermal barrier coating

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Min; Kim, Hak Joon; Song, Sung Jin; Seok, Chang Seong; Lee, Yeong Ze [Dept. of Mechanical Engineering, Sungkyunkwan University, Suwon (Korea, Republic of); Lee, Seul Gi [LG Electronics, Seoul (Korea, Republic of)

    2016-06-15

    A thermal barrier coating (TBC) has been widely applied to machine components working under high temperature as a thermal insulator owing to its critical financial and safety benefits to the industry. However, the nondestructive evaluation of TBC damage is not easy since sensing of the microscopic change that occurs on the TBC is required during an evaluation. We designed an eddy current probe for evaluating damage on a TBC based on the finite element method (FEM) and validated its performance through an experiment. An FEM analysis predicted the sensitivity of the probe, showing that impedance change increases as the TBC thermally degrades. In addition, the effect of the magnetic shield concentrating magnetic flux density was also observed. Finally, experimental validation showed good agreement with the simulation result.

  14. Artificial Warming of Arctic Meadow under Pollution Stress: Experimental design

    Science.gov (United States)

    Moni, Christophe; Silvennoinen, Hanna; Fjelldal, Erling; Brenden, Marius; Kimball, Bruce; Rasse, Daniel

    2014-05-01

    Boreal and arctic terrestrial ecosystems are central to the climate change debate, notably because future warming is expected to be disproportionate as compared to world averages. Likewise, greenhouse gas (GHG) release from terrestrial ecosystems exposed to climate warming is expected to be the largest in the arctic. Artic agriculture, in the form of cultivated grasslands, is a unique and economically relevant feature of Northern Norway (e.g. Finnmark Province). In Eastern Finnmark, these agro-ecosystems are under the additional stressor of heavy metal and sulfur pollution generated by metal smelters of NW Russia. Warming and its interaction with heavy metal dynamics will influence meadow productivity, species composition and GHG emissions, as mediated by responses of soil microbial communities. Adaptation and mitigation measurements will be needed. Biochar application, which immobilizes heavy metal, is a promising adaptation method to promote positive growth response in arctic meadows exposed to a warming climate. In the MeadoWarm project we conduct an ecosystem warming experiment combined to biochar adaptation treatments in the heavy-metal polluted meadows of Eastern Finnmark. In summary, the general objective of this study is twofold: 1) to determine the response of arctic agricultural ecosystems under environmental stress to increased temperatures, both in terms of plant growth, soil organisms and GHG emissions, and 2) to determine if biochar application can serve as a positive adaptation (plant growth) and mitigation (GHG emission) strategy for these ecosystems under warming conditions. Here, we present the experimental site and the designed open-field warming facility. The selected site is an arctic meadow located at the Svanhovd Research station less than 10km west from the Russian mining city of Nikel. A splitplot design with 5 replicates for each treatment is used to test the effect of biochar amendment and a 3oC warming on the Arctic meadow. Ten circular

  15. Nanorobotic Applications in Medicine: Current Proposals and Designs.

    Science.gov (United States)

    Saadeh, Yamaan; Vyas, Dinesh

    2014-06-01

    Advances in technology have increased our ability to manipulate the world around us on an ever-decreasing scale. Nanotechnologies are rapidly emerging within the realm of medicine, and this subfield has been termed nanomedicine. Use of nanoparticle technology has become familiar and increasingly commonplace, especially with pharmaceutical technology. An exciting and promising area of nanotechnological development is the building of nanorobots, which are devices with components manufactured on the nanoscale. This area of study is replete with potential applications, many of which are currently being researched and developed. The goal of this paper is to give an introduction to the emerging field of nanorobotics within medicine, and provide a review of the emerging applications of nanorobotics to fields ranging from neurosurgery to dentistry.

  16. Experimental Investigations on PV Powered SVM-DTC Induction Motor without AC Phase Current Sensors

    Directory of Open Access Journals (Sweden)

    T. Muthamizhan

    2014-05-01

    Full Text Available The paper presents a low-cost, phase-current reconstruction algorithm for space vector modulated direct torque controlled induction motor using the information obtained from only one shunt resistor which is in series with low side switches in a conventional three-phase inverter. The aim is to develop a low-cost high - performance induction motor drive. It uses the dc-link voltage and dc current to reconstruct the stator currents needed to estimate the motor flux and the electromagnetic torque. Photovoltaic arrays convert solar power to dc electric power; uses chopper and dc-ac inverter to fed three phase Induction Motor. The chopper used here is current fed full bridge boost dc-dc converter, which is preferred and extensively used in high voltage applications and advantageous over voltage fed converters. The inverter switches are controlled by PWM techniques obtained from SVM-DTC of IM. The experimental investigations are given to prove the ability of the proposed scheme of reproducing the performances of a SVM- DTC IM drive.

  17. Safety and efficacy of transcranial direct current stimulation in acute experimental ischemic stroke.

    Science.gov (United States)

    Peruzzotti-Jametti, Luca; Cambiaghi, Marco; Bacigaluppi, Marco; Gallizioli, Mattia; Gaude, Edoardo; Mari, Silvia; Sandrone, Stefano; Cursi, Marco; Teneud, Luis; Comi, Giancarlo; Musco, Giovanna; Martino, Gianvito; Leocani, Letizia

    2013-11-01

    Transcranial direct current stimulation is emerging as a promising tool for the treatment of several neurological conditions, including cerebral ischemia. The therapeutic role of this noninvasive treatment is, however, limited to chronic phases of stroke. We thus ought to investigate whether different stimulation protocols could also be beneficial in the acute phase of experimental brain ischemia. The influence of both cathodal and anodal transcranial direct current stimulation in modifying brain metabolism of healthy mice was first tested by nuclear magnetic resonance spectroscopy. Then, mice undergoing transient proximal middle cerebral artery occlusion were randomized and treated acutely with anodal, cathodal, or sham transcranial direct current stimulation. Brain metabolism, functional outcomes, and ischemic lesion volume, as well as the inflammatory reaction and blood brain barrier functionality, were analyzed. Cathodal stimulation was able, if applied in the acute phase of stroke, to preserve cortical neurons from the ischemic damage, to reduce inflammation, and to promote a better clinical recovery compared with sham and anodal treatments. This finding was attributable to the significant decrease of cortical glutamate, as indicated by nuclear magnetic resonance spectroscopy. Conversely, anodal stimulation induced an increase in the postischemic lesion volume and augmented blood brain barrier derangement. Our data indicate that transcranial direct current stimulation exerts a measurable neuroprotective effect in the acute phase of stroke. However, its timing and polarity should be carefully identified on the base of the pathophysiological context to avoid potential harmful side effects.

  18. Experimentation and Optimization of Surface Roughness in WEDM Process using Full Factorial Design integrated PCA Approach

    Directory of Open Access Journals (Sweden)

    Rismaya Kumar Mishra

    2016-04-01

    Full Text Available Application of WEDM is growing rapidly since the last three decades due its several advantages and applicability of the process to produce complicated intrinsic, extrinsic shapes of miniaturized size, so there is a need to analyze and optimize the process. In this research work the experiments were conducted using the general full factorial design methodology with 48 experimental runs. The values response parameters Ra, Rq and Rz were measured and the effect of process parameters wire type, wire tension, power, pulse on time and discharge current on these responses were studied qualitatively and quantitatively using main effect plots, interaction plots and ANOVA. Finally the optimal process parameter setting for responses were found by using full factorial design integrated PCA Approach.

  19. Experimental and theoretical investigations on the singularity of the intensity factor of the current in high temperature superconductors

    Science.gov (United States)

    Zhang, Xingyi; Huang, Yi; Zhou, Jun; Zhou, Youhe

    2013-08-01

    This paper presents experimental and analytical investigations into the distribution of current around a through-edge crack located in an infinitely long cylindrical high temperature superconductor (HTS) on the basis of the Bean model. Current distributions around the crack in the HTS without deformation are obtained by a simple conformal mapping. It is shown that the current is singular at the tip of the crack. An intensity factor of the current is introduced to characterize the singularity, the order of which is equal to -1. Additionally, an experimental verification according to the trapped field distributions around the crack is carried out, and the experimental results show little difference with the theoretical analysis.

  20. Assessment of 'dry skin': current bioengineering methods and test designs.

    Science.gov (United States)

    Fischer, T W; Wigger-Alberti, W; Elsner, P

    2001-01-01

    Dry skin is a frequent problem in dermatology and a sign of dysfunction of the epidermis, especially of the stratum corneum as the morphological equivalent of the skin barrier. It may occur as an individual disposition or as the leading symptom of atopic dermatitis or ichthyosis. Besides the visual examination of the skin, various bioengineering methods have been developed to assess the different pathological and adaptive changes in the skin. In addition to the assessment of skin humidity, barrier function and desquamation, the quantification of skin surface topography and the mechanical properties of skin are suitable methods to characterize a dry skin condition. For clinical assessment of moisturizing products and emollients the parameters of investigation have to be defined and integrated in an adapted study design depending on the composition and content of the active agent in the test product. Newly developed cosmetic products have to be investigated for safety and efficacy. Modern bioengineering methods are suitable to fulfill these challenges.

  1. Transcranial direct-current stimulation induced in stroke patients with aphasia: a prospective experimental cohort study

    Directory of Open Access Journals (Sweden)

    Michele Devido Santos

    Full Text Available CONTEXT AND OBJECTIVE: Previous animal and human studies have shown that transcranial direct current stimulation can induce significant and lasting neuroplasticity and may improve language recovery in patients with aphasia. The objective of the study was to describe a cohort of patients with aphasia after stroke who were treated with transcranial direct current stimulation. DESIGN AND SETTING: Prospective cohort study developed in a public university hospital. METHODS: Nineteen patients with chronic aphasia received 10 transcranial direct current stimulation sessions lasting 20 minutes each on consecutive days, using a current of 2 mA. The anode was positioned over the supraorbital area and the cathode over the contralateral motor cortex. The following variables were analyzed before and after the 10 neuromodulation sessions: oral language comprehension, copying, dictation, reading, writing, naming and verbal fluency. RESULTS: There were no adverse effects in the study. We found statistically significant differences from before to after stimulation in relation to simple sentence comprehension (P = 0.034, naming (P = 0.041 and verbal fluency for names of animals (P = 0.038. Improved scores for performing these three tasks were seen after stimulation. CONCLUSIONS: We observed that excitability of the primary motor cortex through transcranial direct current stimulation was associated with effects on different aspects of language. This can contribute towards future testing in randomized controlled trials.

  2. New approaches in the design of magnetic tweezers–current magnetic tweezers

    Energy Technology Data Exchange (ETDEWEB)

    Bessalova, Valentina [Lomonosov Moscow State University, Leninskie Gory 1-2, 119991 Moscow (Russian Federation); Perov, Nikolai [Lomonosov Moscow State University, Leninskie Gory 1-2, 119991 Moscow (Russian Federation); Immanuel Kant Baltic Federal University, Nevskogo 14, 236004 Kaliningrad (Russian Federation); Rodionova, Valeria [Immanuel Kant Baltic Federal University, Nevskogo 14, 236004 Kaliningrad (Russian Federation); National University of Science and Technology ' MISiS' , Leninsky Prospect 4, 119049 Moscow (Russian Federation)

    2016-10-01

    The main advantages of the magnetic tweezers are the low price and simplicity of use. However the range of their application is reduced due to shortcomings like, for example, the remanent induction of the core and interaction between ferromagnetic cores. We present the new design of magnetic tweezers–Current Magnetic Tweezers (CMT) that allow particle manipulation by means of the magnetic field generated by the electric currents flowing through the non-magnetic wires. Arranging wires in different geometric shapes allows the particle movement either in two or three dimensions. Forces acting on the magnetic particles with the magnetic moment of 2·10{sup −11} A m{sup 2} at distances up to 1 mm had been experimentally measured. It is established that a current of about 1 A at a 1 mm distance generates force of (approximately) 3 pN which is consistent with theoretical estimates. - Highlights: • We suggest the idea and the results of the test the prototype based on 3 wire's system that allows manipulation of nanoparticles on XY plane.

  3. Facility for Advanced Accelerator Experimental Tests at SLAC (FACET) Conceptual Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Amann, J.; Bane, K.; /SLAC

    2009-10-30

    This Conceptual Design Report (CDR) describes the design of FACET. It will be updated to stay current with the developing design of the facility. This CDR begins as the baseline conceptual design and will evolve into an 'as-built' manual for the completed facility. The Executive Summary, Chapter 1, gives an introduction to the FACET project and describes the salient features of its design. Chapter 2 gives an overview of FACET. It describes the general parameters of the machine and the basic approaches to implementation. The FACET project does not include the implementation of specific scientific experiments either for plasma wake-field acceleration for other applications. Nonetheless, enough work has been done to define potential experiments to assure that the facility can meet the requirements of the experimental community. Chapter 3, Scientific Case, describes the planned plasma wakefield and other experiments. Chapter 4, Technical Description of FACET, describes the parameters and design of all technical systems of FACET. FACET uses the first two thirds of the existing SLAC linac to accelerate the beam to about 20GeV, and compress it with the aid of two chicanes, located in Sector 10 and Sector 20. The Sector 20 area will include a focusing system, the generic experimental area and the beam dump. Chapter 5, Management of Scientific Program, describes the management of the scientific program at FACET. Chapter 6, Environment, Safety and Health and Quality Assurance, describes the existing programs at SLAC and their application to the FACET project. It includes a preliminary analysis of safety hazards and the planned mitigation. Chapter 7, Work Breakdown Structure, describes the structure used for developing the cost estimates, which will also be used to manage the project. The chapter defines the scope of work of each element down to level 3.

  4. Experimental Determination of DT Yield in High Current DD Dense Plasma Focii

    Energy Technology Data Exchange (ETDEWEB)

    Lowe, D. R. [National Security Technologies, LLC; Hagen, E. C. [National Security Technologies, LLC; Meehan, B. T. [National Security Technologies, LLC; Springs, R. K. [University of Nevada, Las Vegas; O' Brien, R. J. [University of Nevada, Las Vegas

    2013-06-18

    Dense Plasma Focii (DPF), which utilize deuterium gas to produce 2.45 MeV neutrons, may in fact also produce DT fusion neutrons at 14.1 MeV due to the triton production in the DD reaction. If beam-target fusion is the primary producer of fusion neutrons in DPFs, it is possible that ejected tritons from the first pinch will interact with the second pinch, and so forth. The 2 MJ DPF at National Security Technologies’ Losee Road Facility is able to, and has produced, over 1E12 DD neutrons per pulse, allowing an accurate measurement of the DT/DD ratio. The DT/DD ratio was experimentally verified by using the (n,2n) reaction in a large piece of praseodymium metal, which has a threshold reaction of 8 MeV, and is widely used as a DT yield measurement system1. The DT/DD ratio was experimentally determined for over 100 shots, and then compared to independent variables such as tube pressure, number of pinches per shot, total current, pinch current and charge voltage.

  5. Experimental demonstration of a new radiation mechanism: emission by an oscillating, accelerated, superluminal polarization current

    CERN Document Server

    Ardavan, A; Ardavan, H; Fopma, J; Halliday, D; Hayes, W

    2004-01-01

    We describe the experimental implementation of a superluminal ({\\it i.e.} faster than light {\\it in vacuo}) polarization current distribution that both oscillates and undergoes centripetal acceleration. Theoretical treatments lead one to expect that the radiation emitted from each volume element of such a polarization current will comprise a \\v{C}erenkov-like envelope with two sheets that meet along a cusp. The emission from the experimental machine is in good agreement with these expectations, the combined effect of the volume elements leading to tightly-defined beams of a well-defined geometry, determined by the source speed and trajectory. In addition, over a restricted range of angles, we detect the presence of cusps in the emitted radiation. These are due to the detection over a short time period (in the laboratory frame) of radiation emitted over a considerably longer period of source time. Consequently, the intensity of the radiation at these angles was observed to decline more slowly with increasing d...

  6. Design of a Combined Ballistic Simulator and Primer Force Experimental Fixture

    Science.gov (United States)

    2015-08-01

    ARL-MR-0896 ●AUG 2015 US Army Research Laboratory Design of a Combined Ballistic Simulator and Primer Force Experimental Fixture...SUBTITLE Design of a Combined Ballistic Simulator and Primer Force Experimental Fixture 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT...Contents List of Figures iv Acknowledgments v 1. Introduction 1 2. Background 1 3. Technical Approach 4 3.1 Hardware Design 4 3.2 Experimental Setup

  7. Efficient Experimental Design Strategies in Toxicology and Bioassay

    Directory of Open Access Journals (Sweden)

    Timothy E. O'Brien

    2016-06-01

    Full Text Available Modelling in bioassay often uses linear or nonlinear logistic regression models, and relative potency is often the focus when two or more compounds are to be compared.  Estimation in these settings is typically based on likelihood methods.  Here, we focus on the 3-parameter model representation given in Finney (1978 in which the relative potency is a model parameter.  Using key matrix results and the general equivalence theorem of Kiefer & Wolfowitz (1960, this paper establishes key design properties of the optimal design for relative potency using this model.  We also highlight aspects of subset designs for the relative potency parameter and extend geometric designs to efficient design settings of bioassay.  These latter designs are thus useful for both parameter estimation and checking for goodness-of-fit.  A typical yet insightful example is provided from the field of toxicology to illustrate our findings.

  8. Design and Measurement Methodology for a Sub-picoampere Current Digitiser

    CERN Document Server

    Voulgari, Evgenia; Anghinolfi, Francis; Krummenacher, François; Kayal, Maher

    2015-01-01

    This paper introduces some design and measurement techniques that were used in the design and the testing of an ASIC for ultra-low current sensing. The idea behind this paper is to present the limitations in sub-picoampere current measurements and demonstrate an ASIC that can accurately measure the different sources of leakage currents and the methodology of measuring. Then the leakage current can be subtracted or compensated in order to accurately measure the ultra-low current that is generated from a sensor/detector. The proposed ASIC can measure currents as low as -50 fA, a value well below similar ASIC implementations.

  9. Counter-current membrane reactor for WGS process: Membrane design

    Energy Technology Data Exchange (ETDEWEB)

    Piemonte, Vincenzo; Favetta, Barbara [Department of Chemical Engineering Materials and Environment, University of Rome ' ' La Sapienza' ' , via Eudossiana 18, 00184 Rome (Italy); De Falco, Marcello [Faculty of Engineering, University Campus Bio-Medico of Rome, via Alvaro del Portillo 21, 00128 Rome (Italy); Basile, Angelo [CNR-ITM, c/o University of Calabria, Via Pietro Bucci, Cubo 17/C, 87030 Rende (CS) (Italy)

    2010-11-15

    Water gas shift (WGS) is a thermodynamically limited reaction which has to operate at low temperatures, reducing kinetics rate and increasing the amount of catalyst required to reach valuable CO conversions. It has been widely demonstrated that the integration of hydrogen selective membranes is a promising way to enhance WGS reactors performance: a Pd-based MR operated successfully overcoming the thermodynamic constraints of a traditional reactor thanks to the removal of hydrogen from reaction environment. In the first part of a MR, the H{sub 2} partial pressure starts from a minimum value since the reaction has not started. As a consequence, if the carrier gas in the permeation zone is sent in counter-current, which is the most efficient configuration, in the first reactor section the H{sub 2} partial pressure in reaction zone is low while in the permeation zone is high, potentially implying back permeation. This means a bad utilization of the first part of the membrane area and thus, a worsening of the MR performance with lower H{sub 2} recovery and lower CO conversion with respect to the case in which the whole selective surface is properly used. To avoid this problem different MR configurations were evaluated by a 1-D pseudo-homogeneous model, validated with WGS industrial data reported in scientific literature. It was demonstrated that the permeated H{sub 2} flow rate per membrane surface, i.e. the membrane flux, strongly improves if selective membrane is placed only in the second part of the reactor: in fact, if the membrane is placed at L{sub m}/L{sub tot} = 0.5, the membrane flux is 0.2 kmol/(m{sup 2}h) about, if it is placed along all reactor tube (L{sub m}/L{sub tot} = 1), flux is 0.05 kmol/(m{sup 2}h). The effect of the L/D reactor ratio and of the reactor wall temperature on the CO conversion were also assessed. (author)

  10. Use of Experimental Design for Peuhl Cheese Process Optimization ...

    African Journals Online (AJOL)

    Devika

    added (7 mL), heating temperature (84.12°C) and heating time (15 min). When these optimal ... conditions constitute one of the major obstacles for ... a two levels factorial design;. • a design of ... balance (Sartorius Gmbh, Göttingen, Germany),.

  11. Clinical and experimental studies on polyherbal formulations for diabetes:current status and future prospective

    Institute of Scientific and Technical Information of China (English)

    Ahmad Ghorbani

    2014-01-01

    Diabetes is a leading cause of morbidity and mortality in the world. There is currently an active search for antidiabetic drugs with greater effectiveness with fewer and less adverse side effects. Although numerous individual herbs have been experimentally or clinically reported to possess antidiabetic effects, considerably less research has been conducted on polyherbal compounds. It is believed that herbal compounds containing multiple plant products have synergistic antidiabetic effects and could enhance the desired actions. Several polyherbal formulations have been studied as therapeutic agents in diabetes management. To describe the current state of research on polyherbal compounds in the treatment of diabetes, an extensive review of literature was undertaken on several major databases. This paper presents what is known about the efifcacy of these polyherbal formulations and compare their antidiabetic effects with those of current oral hypoglycemic drugs as reference. The percent decrease in blood glucose, lipids and other biochemical parameters achieved by each product in diabetic animals and patients is reported. Also, the possible mechanisms responsible for hypoglycemic action of polyherbal formulations are discussed.

  12. An innovative magnetorheological damper for automotive suspension: from design to experimental characterization

    Science.gov (United States)

    Sassi, Sadok; Cherif, Khaled; Mezghani, Lotfi; Thomas, Marc; Kotrane, Asma

    2005-08-01

    The development of a powerful new magnetorheological fluid (MRF), together with recent progress in the understanding of the behavior of such fluids, has convinced researchers and engineers that MRF dampers are among the most promising devices for semi-active automotive suspension vibration control, because of their large force capacity and their inherent ability to provide a simple, fast and robust interface between electronic controls and mechanical components. In this paper, theoretical and experimental studies are performed for the design, development and testing of a completely new MRF damper model that can be used for the semi-active control of automotive suspensions. The MR damper technology presented in this paper is based on a completely new approach where, in contrast to in the conventional solutions where the coil axis is usually superposed on the damper axis and where the inner cylindrical housing is part of the magnetic circuit, the coils are wound in a direction perpendicular to the damper axis. The paper investigates approaches to optimizing the dynamic response and provides experimental verification. Both experimental and theoretical results have shown that, if this particular model is filled with an 'MRF 336AG' MR fluid, it can provide large controllable damping forces that require only a small amount of energy. For a magnetizing system with four coils, the damping coefficient could be increased by up to three times for an excitation current of only 2 A. Such current could be reduced to less than 1 A if the magnetizing system used eight small cores. In this case, the magnetic field will be more powerful and more regularly distributed. In the presence of harmonic excitation, such a design will allow the optimum compromise between comfort and stability to be reached over different intervals of the excitation frequencies.

  13. Experimental study on hydrodynamic characteristics of vertical-axis floating tidal current energy power generation device

    Science.gov (United States)

    Ma, Yong; Li, Teng-fei; Zhang, Liang; Sheng, Qi-hu; Zhang, Xue-wei; Jiang, Jin

    2016-10-01

    To study the characteristics of attenuation, hydrostatic towage and wave response of the vertical-axis floating tidal current energy power generation device (VAFTCEPGD), a prototype is designed and experiment is carried out in the towing tank. Free decay is conducted to obtain attenuation characteristics of the VAFTCEPGD, and characteristics of mooring forces and motion response, floating condition, especially the lateral displacement of the VAFTCEPGD are obtained from the towing in still water. Tension response of the #1 mooring line and vibration characteristics of the VAFTCEPGD in regular waves as well as in level 4 irregular wave sea state with the current velocity of 0.6 m/s. The results can be reference for theoretical study and engineering applications related to VAFTCEPGD.

  14. Leveraging the Experimental Method to Inform Solar Cell Design

    Science.gov (United States)

    Rose, Mary Annette; Ribblett, Jason W.; Hershberger, Heather Nicole

    2010-01-01

    In this article, the underlying logic of experimentation is exemplified within the context of a photoelectrical experiment for students taking a high school engineering, technology, or chemistry class. Students assume the role of photochemists as they plan, fabricate, and experiment with a solar cell made of copper and an aqueous solution of…

  15. Experimental validation of micro endmill design for hard milling application

    NARCIS (Netherlands)

    Li, P.; Hoogstrate, A.M.; Oosterling, J.A.J.; Langen, H.H.; Munnig Schmidt, R.

    2008-01-01

    Abstract: In experimental investigations of micro milling of hardened tool steel SAE H11, with a hardness of 56 HRC, with commercially available micro square endmills of Ø 0.5mm, it was observed that the endmills suffered from severe tool wear/failure. Because of these problems, the quality of the m

  16. Leveraging the Experimental Method to Inform Solar Cell Design

    Science.gov (United States)

    Rose, Mary Annette; Ribblett, Jason W.; Hershberger, Heather Nicole

    2010-01-01

    In this article, the underlying logic of experimentation is exemplified within the context of a photoelectrical experiment for students taking a high school engineering, technology, or chemistry class. Students assume the role of photochemists as they plan, fabricate, and experiment with a solar cell made of copper and an aqueous solution of…

  17. Gunnar Aagaard Andersen: Commercial Design and Experimental Art

    DEFF Research Database (Denmark)

    Gether, Vibeke Petersen

    2016-01-01

    in Copenhagen and the magazine Mobilia. These enterprises were pioneers within both the commercial–industrial creative field and experimental art from the 1950s. The industrial process, from idea and experiment to production,as well as the expanded field of visual art, was demonstrated in concrete painting...

  18. Fuzzy logic control algorithms for MagneShock semiactive vehicle shock absorbers: design and experimental evaluations

    Science.gov (United States)

    Craft, Michael J.; Buckner, Gregory D.; Anderson, Richard D.

    2003-07-01

    Automotive ride quality and handling performance remain challenging design tradeoffs for modern, passive automobile suspension systems. Despite extensive published research outlining the benefits of active vehicle suspensions in addressing this tradeoff, the cost and complexity of these systems frequently prohibit commercial adoption. Semi-active suspensions can provide performance benefits over passive suspensions without the cost and complexity associated with fully active systems. This paper outlines the development and experimental evaluation of a fuzzy logic control algorithm for a commercial semi-active suspension component, Carrera's MagneShockTM shock absorber. The MagneShockTM utilizes an electromagnet to change the viscosity of magnetorheological (MR) fluid, which changes the damping characteristics of the shock. Damping for each shock is controlled by manipulating the coil current using real-time algorithms. The performance capabilities of fuzzy logic control (FLC) algorithms are demonstrated through experimental evaluations on a passenger vehicle. Results show reductions of 25% or more in sprung mass absorbed power (U.S. Army 6 Watt Absorbed Power Criterion) as compared to typical passive shock absorbers over urban terrains in both simulation and experimentation. Average sprung-mass RMS accelerations were also reduced by as much as 9%, but usually with an increase in total suspension travel over the passive systems. Additionally, a negligible decrease in RMS tire normal force was documented through computer simulations. And although the FLC absorbed power was comparable to that of the fixed-current MagneShockTM the FLC revealed reduced average RMS sprung-mass accelerations over the fixed-current MagneShocks by 2-9%. Possible means for improvement of this system include reducing the suspension spring stiffness and increasing the dynamic damping range of the MagneShockTM.

  19. Experimental Investigation and Modelling for the Optimisation of Conduction Cooled HTS Hybrid Current Leads for SMES

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    It′s important that HTS tapes have lower thermal conductivity and higher transversal resistivity in order to reduce the heat leaks conducted along the tapes and AC losses in the high temperature superconducting system conduction-cooled by GM coolers. This paper presents an experimental investigation into the effects of pure Ag and AgAu alloys sheath materials on the properties of Bi(2223) multifilamentary tapes and the optimisation of conduction-cooled hybrid current leads made from copper and Bi(2223)/Ag or Bi(2223)/AgAu tapes. The thermal conductivity of the tapes were measured by cryogenic steady heat flux method and the resistance was measured by using standard DC four-probe method at low temperature. The results showed that the reduction of thermal conductivity by the addition of Au into the sheath material of Bi(2223) tapes was 650%, 750% and 850% lower than that of pure Ag sheathed Bi(2223) tapes and the increase of resistivity was 4.9, 10 and 19.4 times higher than that of pure Ag for the addition of 2.20%, 5.70% and 10.70%Au(atom ratio) respectively. And the study also attempts to optimise thermodynamically the conduction-cooled hybrid current lead by using a developed model, which took the irreversibility of commercial GM coolers, the contact resistance and thermal conductance into account. Predictions from the model showed that AgAu alloys were suitable candidate materials to replace Ag as sheath material of Bi(2223) tapes applied in HTS current leads. In addition, Bi(2223)/AgAu was a suitable material to be applied as the HTS section of hybrid current leads in conduction-cooled superconducting electric systems.

  20. Experimental design for research on shock-turbulence interaction

    Science.gov (United States)

    Radcliffe, S. W.

    1969-01-01

    Report investigates the production of acoustic waves in the interaction of a supersonic shock and a turbulence environment. The five stages of the investigation are apparatus design, development of instrumentation, preliminary experiment, turbulence generator selection, and main experiments.

  1. Experimental techniques for design of impact-resistant material (poster)

    NARCIS (Netherlands)

    Fan, J.; Weerheijm, J.; Sluys, L.J.

    2013-01-01

    Some polymers are not only transparent and lightweight, but also impact and ballistic resistant. Designing and preparing such polymeric materials with a high impact‐resistant performance is of importance to e.g. aviation, military and windscreen applications.

  2. Experimental techniques for design of impact-resistant material (poster)

    NARCIS (Netherlands)

    Fan, J.; Weerheijm, J.; Sluys, L.J.

    2013-01-01

    Some polymers are not only transparent and lightweight, but also impact and ballistic resistant. Designing and preparing such polymeric materials with a high impact‐resistant performance is of importance to e.g. aviation, military and windscreen applications.

  3. Sources of Experimental Variation in 2-D Maps: The Importance of Experimental Design in Gel-Based Proteomics.

    Science.gov (United States)

    Valcu, Cristina-Maria; Valcu, Mihai

    2016-01-01

    The success of proteomic studies employing 2-D maps largely depends on the way surveys and experiments have been organized and performed. Planning gel-based proteomic experiments involves the selection of equipment, methodology, treatments, types and number of samples, experimental layout, and methods for data analysis. A good experimental design will maximize the output of the experiment while taking into account the biological and technical resources available. In this chapter we provide guidelines to assist proteomics researchers in all these choices and help them to design quantitative 2-DE experiments.

  4. Physics Design of Water Moderator Criticality Assembly in Experimental Research About ADS

    Institute of Scientific and Technical Information of China (English)

    LV; Niu

    2013-01-01

    In order to meet the experimental demand of ADS research,we need to design a suitable criticality assembly.The key problem of the design work is the core design,we design a criticality assembly with the water moderator according to available nuclear material(Fig.1).The theoretical calculation have been

  5. Experimental Study on Vortex-Induced Vibrations of Submarine Pipeline near Seabed Boundary in Ocean Currents

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Unlike most previous studies on vortex-induced vibrations of a cylinder far from a boundary, this paper focuses on the influences of close proximity of a submarine pipeline to a rigid seabed boundary upon the dynamic responses of the pipeline in ocean currents. The effects of gap-to-diameter ratio and those of the stability parameter on the amplitude and frequency responses of a pipeline are investigated experimentally with a novel hydro-elastic facility. A comparison is made between the present experimental results of the amplitude and frequency responses for the pipes with seabed boundary effects and those for wall-free cylinders given by Govardhan and Williamson (2000) and Anand (1985). The comparison shows that the close proximity of a pipeline to seabed has much influence on the vortex-induced vibrations of the pipeline. Both the width of the lock-in ranges in terms of Vr and the dimensionless amplitude ratio Amax/D become larger with the decrease of the gap-to-diameter ratio e/D. Moreover, the vibration of the pipeline becomes easier to occur and its amplitude response becomes more intensive with the decrease of the stability parameter, while the pipeline frequency responses are affected slightly by the stability parameter.

  6. Experimental pain processing in individuals with cognitive impairment: current state of the science.

    Science.gov (United States)

    Defrin, Ruth; Amanzio, Martina; de Tommaso, Marina; Dimova, Violeta; Filipovic, Sasa; Finn, David P; Gimenez-Llort, Lydia; Invitto, Sara; Jensen-Dahm, Christina; Lautenbacher, Stefan; Oosterman, Joukje M; Petrini, Laura; Pick, Chaim G; Pickering, Gisele; Vase, Lene; Kunz, Miriam

    2015-08-01

    Cognitive impairment (CI) can develop during the course of ageing and is a feature of many neurological and neurodegenerative diseases. Many individuals with CI have substantial, sustained, and complex health care needs, which frequently include pain. However, individuals with CI can have difficulty communicating the features of their pain to others, which in turn presents a significant challenge for effective diagnosis and treatment of their pain. Herein, we review the literature on responsivity of individuals with CI to experimental pain stimuli. We discuss pain responding across a large number of neurological and neurodegenerative disorders in which CI is typically present. Overall, the existing data suggest that pain processing is altered in most individuals with CI compared with cognitively intact matched controls. The precise nature of these alterations varies with the type of CI (or associated clinical condition) and may also depend on the type of pain stimulation used and the type of pain responses assessed. Nevertheless, it is clear that regardless of the etiology of CI, patients do feel noxious stimuli, with more evidence for hypersensitivity than hyposensitivity to these stimuli compared with cognitively unimpaired individuals. Our current understanding of the neurobiological mechanisms underpinning these alterations is limited but may be enhanced through the use of animal models of CI, which also exhibit alterations in nociceptive responding. Further research using additional behavioural indices of pain is warranted. Increased understanding of altered experimental pain processing in CI will facilitate the development of improved diagnostic and therapeutic approaches for pain in individuals with CI.

  7. Nanowire piezo-phototronic photodetector: theory and experimental design.

    Science.gov (United States)

    Liu, Ying; Yang, Qing; Zhang, Yan; Yang, Zongyin; Wang, Zhong Lin

    2012-03-15

    The piezo-phototronic effect is about the use of the inner crystal piezoelectric potential to tune/control charge carrier generation, separation, transport and/or recombination in optoelectronic devices. In this paper, a theoretical model for describing the characteristics of a metal-nanowire-metal structured piezo-phototronic photodetector is constructed. Numerical simulations fit well to the experimental results of a CdS and ZnO nanowire based visible and UV detector, respectively.

  8. An Experimental Investigation of Passive Variable-Pitch Vertical-Axis Ocean Current Turbine

    Directory of Open Access Journals (Sweden)

    Ridho Hantoro

    2011-04-01

    Full Text Available Vertical-axis hydrokinetic turbines with fixed pitch blades typically suffer from poor starting torque, low efficiency and shaking due to large fluctuations in both radial and tangential force with azimuth angle. Maximizing the turbine power output can be achieved only if the mechanism of generation of the hydrodynamic force on the blades is clearly identified and tools to design high-performance rotors are developed. This paper describes an initial experimental investigation to understand more of the performance on vertical-axis turbine related to the effect of fixed-pitch and passive variable-pitch application using airfoil NACA 0018. Comparative analysis according to aspects of rotation and tip speed ratios was discussed. Information regarding the changes of foil position in passive variable-pitch during rotation at a limited range of flow velocity variations test was obtained and analyzed.

  9. Design and Preparation of RF System for the Lower Hybrid Fast Wave Heating and Current Drive Research on VEST

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sun Ho; Jeong, Seung Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Lee, Hyun Woo; Lee, Byung Je [Kwang Woon University, Chuncheon (Korea, Republic of); Jo, Jong Gab; Lee, Hyun Young; Hwang, Yong Seok [Seoul National University, Seoul (Korea, Republic of)

    2015-10-15

    Continuous current drive is one of the key issues for tokamak to be a commercial fusion reactor. As a part of new and efficient current drive concept research by using a Lower Hybrid Fast Wave (LHFW), the experimental study is planned on Versatile Experiment Spherical Torus (VEST) and a RF system is being developed in collaboration with Kwang Woon University (KWU), Korea Accelerator Plasma Research Association (KAPRA) and Seoul National University (SNU). The LHFW RF system includes UHF band klystron, inter-digital antenna, RF diagnostics and power transmission sub components such as circulator, DC breaker, vacuum feed-thru. The design and preparation status of the RF system will be presented in the meeting in detail. A RF system has been designed and prepared for the experimental study of efficient current drive by using Lower Hybrid Fast Wave. Overall LHFW RF system including diagnostics is designed to deliver about 10 kW in UHF band. And the key hardware components including klystron and antenna are being prepared and designed through the collaboration with KWU, KAPRA and SNU.

  10. Experimental Characterisation of Moreno Cross Slot Couplers for Blass Matrix Design

    Directory of Open Access Journals (Sweden)

    K. Jery Varghese

    1998-10-01

    Full Text Available This paper presents the experimental characterisation of Moreno cross-slot coupler which is the basic building block of multiple beam forming network (Blass matrix. The lack of exact theory of such coupler requires extensive experimental evaluation. A novel test jig has been designed, fabricated and tested for this purpose. The experimental results for different scattering parameters are presented.

  11. Using Propensity Scores in Quasi-Experimental Designs to Equate Groups

    Science.gov (United States)

    Lane, Forrest C.; Henson, Robin K.

    2010-01-01

    Education research rarely lends itself to large scale experimental research and true randomization, leaving the researcher to quasi-experimental designs. The problem with quasi-experimental research is that underlying factors may impact group selection and lead to potentially biased results. One way to minimize the impact of non-randomization is…

  12. "Using Power Tables to Compute Statistical Power in Multilevel Experimental Designs"

    Science.gov (United States)

    Konstantopoulos, Spyros

    2009-01-01

    Power computations for one-level experimental designs that assume simple random samples are greatly facilitated by power tables such as those presented in Cohen's book about statistical power analysis. However, in education and the social sciences experimental designs have naturally nested structures and multilevel models are needed to compute the…

  13. Generalized Design Method for Voltage-Controlled Current-Mode Multifunction Filters

    Directory of Open Access Journals (Sweden)

    I. Lattenberg

    2009-11-01

    Full Text Available In the article, the Generalized Current Follower Transconductance Amplifier (GCFTA element for generalized frequency filter design and a novel active element, the Programmable Current Amplifier (PCA for the realization of the current-mode analog blocks, are presented. The paper also presents a method of general frequency filter design, whereas the basic circuit is a general autonomous circuit using GCFTA, PCA elements and general admittances. The properties of the proposed filter have been verified using PSPICE simulations.

  14. Potential for Ammonia Recapture by Farm Woodlands: Design and Application of a New Experimental Facility

    Directory of Open Access Journals (Sweden)

    Mark R. Theobald

    2001-01-01

    Full Text Available There has been increasing pressure on farmers in Europe to reduce the emissions of ammonia from their land. Due to the current financial climate in which farmers have to operate, it is important to identify ammonia control measures that can be adopted with minimum cost. The planting of trees around farmland and buildings has been identified as a potentially effective and low-cost measure to enhance ammonia recapture at a farm level and reduce long-range atmospheric transport. This work assesses experimentally what fraction of ammonia farm woodlands could potentially remove from the atmosphere. We constructed an experimental facility in southern Scotland to simulate a woodland shelterbelt planted in proximity to a small poultry unit. By measuring horizontal and vertical ammonia concentration profiles within the woodland, and comparing this to the concentration of an inert tracer (SF6 we estimate the depletion of ammonia due to dry deposition to the woodland canopy. Together with measurements of mean ammonia concentrations and throughfall fluxes of nitrogen, this information is used to provide a first estimate of the fraction of emitted ammonia that is recaptured by the woodland canopy. Analysis of these data give a lower limit of recapture of emitted ammonia, at the experimental facility, of 3%. By careful design of shelterbelt woodlands this figure could be significantly higher.

  15. Designing spectrum-splitting dichroic filters to optimize current-matched photovoltaics.

    Science.gov (United States)

    Miles, Alexander; Cocilovo, Byron; Wheelwright, Brian; Pan, Wei; Tweet, Doug; Norwood, Robert A

    2016-03-10

    We have developed an approach for designing a dichroic coating to optimize performance of current-matched multijunction photovoltaic cells while diverting unused light. By matching the spectral responses of the photovoltaic cells and current matching them, substantial improvement to system efficiencies is shown to be possible. A design for use in a concentrating hybrid solar collector was produced by this approach, and is presented. Materials selection, design methodology, and tilt behavior on a curved substrate are discussed.

  16. Experimental determination of two-dimensional critical current density distribution in YBCO coated conductors

    Energy Technology Data Exchange (ETDEWEB)

    Amemiya, Naoyuki; Shinkai, Yoshichika [Faculty of Engineering, Yokohama National University, Tokiwadai, Hodogaya, Yokohama (Japan); Iijima, Yasuhiro; Kakimoto, Kazuomi; Takeda, Kaoru [Materials Research Laboratory, Fujikura Ltd., Kiba, Koto, Tokyo (Japan)

    2001-08-01

    The critical current density (J{sub c}) distribution in YBCO coated conductors is attracting interest from the viewpoint of its influence on their AC loss characteristics as well as from material science and process engineering. A two-dimensional J{sub c} distribution in a YBCO coated conductor made by the IBAD (ion-beam assisted deposition) and the PLD (pulse-laser deposition) method can be determined by the magnetic-knife method with spatial resolutions of 0.2 mm lateral and 10 mm longitudinal directions, respectively. In an up-to-date 80A-class YBCO coated conductor, the J{sub c} is relatively uniform in the central part and reaches mbox{l_brace}7$x$10{sup 9} A m{sup -2}, {r_brace} while the J{sub c} fluctuates spatially in the central part of a tape fabricated earlier and with less critical current. Near the edges of the tapes, the J{sub c} is higher or lower than in the central part and the experimentally determined J{sub c} distributions are far from uniform. This suggests that a presumption of a uniform J{sub c} for AC loss estimations is not always reasonable and can lead to a large error in the estimated AC losses. (author)

  17. Experimental and numerical assessment of low-frequency current distributions from UMTS and GSM mobile phones.

    Science.gov (United States)

    Gosselin, Marie-Christine; Kühn, Sven; Kuster, Niels

    2013-12-07

    The evaluation of the exposure from mobile communication devices requires consideration of electromagnetic fields (EMFs) over a broad frequency range from dc to GHz. Mobile phones in operation have prominent spectral components in the low-frequency (LF) and radio-frequency (RF) ranges. While the exposure to RF fields from mobile phones has been comprehensively assessed in the past, the LF fields have received much less attention. In this study, LF fields from mobile phones are assessed experimentally and numerically for the global system for mobile (GSM) and universal mobile telecommunications system (UMTS) communication systems and conclusions about the global (LF and RF) EMF exposure from both systems are drawn. From the measurements of the time-domain magnetic fields, it was found that the contribution from the audio signal at a normal speech level, i.e., -16 dBm0, is the same order of magnitude as the fields induced by the current bursts generated from the implementation of the GSM communication system at maximum RF output level. The B-field induced by currents in phones using the UMTS is two orders of magnitude lower than that induced by GSM. Knowing that the RF exposure from the UMTS is also two orders of magnitude lower than from GSM, it is now possible to state that there is an overall reduction of the exposure from this communication system.

  18. Experimental diabetes induced by alloxan and streptozotocin: The current state of the art.

    Science.gov (United States)

    Radenković, Miroslav; Stojanović, Marko; Prostran, Milica

    2016-01-01

    Diabetes mellitus is a chronic metabolic disorder with a high prevalence worldwide. Animal models of diabetes represent an important tool in diabetes investigation that helps us to avoid unnecessary and ethically challenging studies in human subjects, as well as to obtain a comprehensive scientific viewpoint of this disease. Although there are several methods through which diabetes can be induced, chemical methods of alloxan- and streptozotocin-induced diabetes represent the most important and highly preferable experimental models for this pathological condition. Therefore, the aim of this article was to review the current knowledge related to quoted models of diabetes, including to this point available information about mechanism of action, particular time- and dose-dependent protocols, frequent problems, as well as major limitations linked to laboratory application of alloxan and sterptozotocin in inducing diabetes. Given that diabetes is known to be closely associated with serious health consequences it is of fundamental importance that current animal models for induction of diabetes should be continuously upgraded in order to improve overall prevention, diagnosis and treatment of this pathological condition.

  19. Numerical and experimental study of the interaction between two marine current turbines

    CERN Document Server

    Mycek, Paul; Germain, Grégory; Pinon, Grégory; Rivoalen, Elie

    2013-01-01

    The understanding of interaction effects between marine energy converters represents the next step in the research process that should eventually lead to the deployment of such devices. Although some a priori considerations have been suggested recently, very few real condition studies have been carried out concerning this issue. Trials were run on 1/30th scale models of three-bladed marine current turbine prototypes in a flume tank. The present work focuses on the case where a turbine is placed at different locations in the wake of a first one. The interaction effects in terms of performance and wake of the second turbine are examined and compared to the results obtained on the case of one single turbine. Besides, a three-dimensional software, based on a vortex method is currently being developed, and will be used in the near future to model more complex layouts. The experimental study shows that the second turbine is deeply affected by the presence of an upstream device and that a compromise between individu...

  20. Optimization of preservatives in a topical formulation using experimental design.

    Science.gov (United States)

    Rahali, Y; Pensé-Lhéritier, A-M; Mielcarek, C; Bensouda, Y

    2009-12-01

    Optimizing the preservative regime for a preparation requires the antimicrobial effectiveness of several preservative combinations to be determined. In this study, three preservatives were tested: benzoic acid, sorbic acid and benzylic alcohol. Their preservative effects were evaluated using the antimicrobial preservative efficacy test (challenge-test) of the European Pharmacopeia (EP). A D-optimal mixture design was used to provide a maximum of information from a limited number of experiments. The results of this study were analysed with the help of the Design Expert software and enabled us to formulate emulsions satisfying both requirements A and B of the EP.

  1. Comparison of experimental and theoretical reaction rail currents, rail voltages, and airgap fields for the linear induction motor research vehicle

    Science.gov (United States)

    Elliott, D. G.

    1977-01-01

    Measurements of reaction rail currents, reaction rail voltages, and airgap magnetic fields in tests of the Linear Induction Motor Research Vehicle (LIMRV) were compared with theoretical calculations from the mesh/matrix theory. It was found that the rail currents and magnetic fields predicted by the theory are within 20 percent of the measured currents and fields at most motor locations in most of the runs, but differ by as much as a factor of two in some cases. The most consistent difference is a higher experimental than theoretical magnetic field near the entrance of the motor and a lower experimental than theoretical magnetic field near the exit. The observed differences between the theoretical and experimental magnetic fields and currents do not account for the differences of as much as 26 percent between the theoretical and experimental thrusts.

  2. A Short Guide to Experimental Design and Analysis for Engineers

    Science.gov (United States)

    2014-04-01

    study of women’s ratings of men based on masculinity , Frederick and Haselton had participants performing octuple duty – providing ratings of...et al. (2012) CK-12 Middle School Math Grade 6. Vol. 1, CK-12 Foundation Mitchell, M. L. and Jolley, J. M. (2010) Research Design Explained. 7th ed

  3. Design and experimental evaluation of cooperative adaptive cruise control

    NARCIS (Netherlands)

    Ploeg, J.; Scheepers, B.T.M.; Nunen, E. van; Wouw, N. van de; Nijmeijer, H.

    2011-01-01

    Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. String-stable behavior is thus considered an essential requirement for the design of automatic

  4. Tokamak experimental power reactor conceptual design. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    1976-08-01

    Volume II contains the following appendices: (1) summary of EPR design parameters, (2) impurity control, (3) plasma computational models, (4) structural support system, (5) materials considerations for the primary energy conversion system, (6) magnetics, (7) neutronics penetration analysis, (8) first wall stress analysis, (9) enrichment of isotopes of hydrogen by cryogenic distillation, and (10) noncircular plasma considerations. (MOW)

  5. Creativity in Advertising Design Education: An Experimental Study

    Science.gov (United States)

    Cheung, Ming

    2011-01-01

    Have you ever thought about why qualities whose definitions are elusive, such as those of a sunset or a half-opened rose, affect us so powerfully? According to de Saussure (Course in general linguistics, 1983), the making of meanings is closely related to the production and interpretation of signs. All types of design, including advertising…

  6. The Inquiry Flame: Scaffolding for Scientific Inquiry through Experimental Design

    Science.gov (United States)

    Pardo, Richard; Parker, Jennifer

    2010-01-01

    In the lesson presented in this article, students learn to organize their thinking and design their own inquiry experiments through careful observation of an object, situation, or event. They then conduct these experiments and report their findings in a lab report, poster, trifold board, slide, or video that follows the typical format of the…

  7. HEAO C-1 gamma-ray spectrometer. [experimental design

    Science.gov (United States)

    Mahoney, W. A.; Ling, J. C.; Willett, J. B.; Jacobson, A. S.

    1978-01-01

    The gamma-ray spectroscopy experiment to be launched on the third High Energy Astronomy Observatory (HEAO C) will perform a complete sky search for narrow gamma-ray line emission to the level of about 00001 photons/sq cm -sec for steady point sources. The design of this experiment and its performance based on testing and calibration to date are discussed.

  8. Design and experimental evaluation of cooperative adaptive cruise control

    NARCIS (Netherlands)

    Ploeg, J.; Scheepers, B.T.M.; Nunen, E. van; Wouw, N. van de; Nijmeijer, H.

    2011-01-01

    Road throughput can be increased by driving at small inter-vehicle time gaps. The amplification of velocity disturbances in upstream direction, however, poses limitations to the minimum feasible time gap. String-stable behavior is thus considered an essential requirement for the design of automatic

  9. OPTIMIZATION OF EXPERIMENTAL DESIGNS BY INCORPORATING NIF FACILITY IMPACTS

    Energy Technology Data Exchange (ETDEWEB)

    Eder, D C; Whitman, P K; Koniges, A E; Anderson, R W; Wang, P; Gunney, B T; Parham, T G; Koerner, J G; Dixit, S N; . Suratwala, T I; Blue, B E; Hansen, J F; Tobin, M T; Robey, H F; Spaeth, M L; MacGowan, B J

    2005-08-31

    For experimental campaigns on the National Ignition Facility (NIF) to be successful, they must obtain useful data without causing unacceptable impact on the facility. Of particular concern is excessive damage to optics and diagnostic components. There are 192 fused silica main debris shields (MDS) exposed to the potentially hostile target chamber environment on each shot. Damage in these optics results either from the interaction of laser light with contamination and pre-existing imperfections on the optic surface or from the impact of shrapnel fragments. Mitigation of this second damage source is possible by identifying shrapnel sources and shielding optics from them. It was recently demonstrated that the addition of 1.1-mm thick borosilicate disposable debris shields (DDS) block the majority of debris and shrapnel fragments from reaching the relatively expensive MDS's. However, DDS's cannot stop large, faster moving fragments. We have experimentally demonstrated one shrapnel mitigation technique showing that it is possible to direct fast moving fragments by changing the source orientation, in this case a Ta pinhole array. Another mitigation method is to change the source material to one that produces smaller fragments. Simulations and validating experiments are necessary to determine which fragments can penetrate or break 1-3 mm thick DDS's. Three-dimensional modeling of complex target-diagnostic configurations is necessary to predict the size, velocity, and spatial distribution of shrapnel fragments. The tools we are developing will be used to set the allowed level of debris and shrapnel generation for all NIF experimental campaigns.

  10. On the construction of experimental designs for a given task by jointly optimizing several quality criteria: Pareto-optimal experimental designs.

    Science.gov (United States)

    Sánchez, M S; Sarabia, L A; Ortiz, M C

    2012-11-19

    Experimental designs for a given task should be selected on the base of the problem being solved and of some criteria that measure their quality. There are several such criteria because there are several aspects to be taken into account when making a choice. The most used criteria are probably the so-called alphabetical optimality criteria (for example, the A-, E-, and D-criteria related to the joint estimation of the coefficients, or the I- and G-criteria related to the prediction variance). Selecting a proper design to solve a problem implies finding a balance among these several criteria that measure the performance of the design in different aspects. Technically this is a problem of multi-criteria optimization, which can be tackled from different views. The approach presented here addresses the problem in its real vector nature, so that ad hoc experimental designs are generated with an algorithm based on evolutionary algorithms to find the Pareto-optimal front. There is not theoretical limit to the number of criteria that can be studied and, contrary to other approaches, no just one experimental design is computed but a set of experimental designs all of them with the property of being Pareto-optimal in the criteria needed by the user. Besides, the use of an evolutionary algorithm makes it possible to search in both continuous and discrete domains and avoid the need of having a set of candidate points, usual in exchange algorithms.

  11. Design and experimental validation of a compact collimated Knudsen source

    CERN Document Server

    Wouters, Steinar H W; Mutsaers, Peter H A; Vredenbregt, Edgar J D

    2015-01-01

    In this paper we discuss the design and performance of a collimated Knudsen source which has the benefit of a simple design over recirculating sources. Measurements of the flux, transverse velocity distribution and brightness at different temperatures were conducted to evaluate the performance. The scaling of the flux and brightness with the source temperature follow the theoretical predictions. The transverse velocity distribution in the transparent operation regime also agrees with the simulated data. The source was found able to produce a flux of $10^{14}$ s$^{-1}$ at a temperature of 433 K. Furthermore the transverse reduced brightness of an ion beam with equal properties as the atomic beam reads $1.7 \\times 10^2$ A/(m${}^2$ sr eV) which is sufficient for our goal: the creation of an ultra-cold ion beam by ionization of a laser-cooled and compressed atomic rubidium beam.

  12. Design and experimental demonstration of optomechanical paddle nanocavities

    CERN Document Server

    Healey, Chris; Wu, Marcelo; Khanaliloo, Behzad; Mitchell, Matthew; Hryciw, Aaron C; Barclay, Paul E

    2015-01-01

    We present the design, fabrication and initial characterization of a paddle nanocavity consisting of a suspended sub-picogram nanomechanical resonator optomechanically coupled to a photonic crystal nanocavity. The optical and mechanical properties of the paddle nanocavity can be systematically designed and optimized, and key characteristics including mechanical frequency easily tailored. Measurements under ambient conditions of a silicon paddle nanocavity demonstrate an optical mode with quality factor $Q_o$ ~ 6000 near 1550 nm, and optomechanical coupling to several mechanical resonances with frequencies $\\omega_m/2\\pi$ ~ 12-64 MHz, effective masses $m_\\text{eff}$ ~ 350-650 fg, and mechanical quality factors $Q_m$ ~ 44-327. Paddle nanocavities are promising for optomechanical sensing and nonlinear optomechanics experiments.

  13. Design and experimental demonstration of optomechanical paddle nanocavities

    Science.gov (United States)

    Healey, Chris; Kaviani, Hamidreza; Wu, Marcelo; Khanaliloo, Behzad; Mitchell, Matthew; Hryciw, Aaron C.; Barclay, Paul E.

    2015-12-01

    We present the design, fabrication, and initial characterization of a paddle nanocavity consisting of a suspended sub-picogram nanomechanical resonator optomechanically coupled to a photonic crystal nanocavity. The optical and mechanical properties of the paddle nanocavity can be systematically designed and optimized, and the key characteristics including mechanical frequency can be easily tailored. Measurements under ambient conditions of a silicon paddle nanocavity demonstrate an optical mode with a quality factor Q o ˜ 6000 near 1550 nm and optomechanical coupling to several mechanical resonances with frequencies ω m / 2 π ˜ 12 - 64 MHz, effective masses m eff ˜ 350 - 650 fg, and mechanical quality factors Q m ˜ 44 - 327 . Paddle nanocavities are promising for optomechanical sensing and nonlinear optomechanics experiments.

  14. High-power CMUTs: design and experimental verification.

    Science.gov (United States)

    Yamaner, F Yalçin; Olçum, Selim; Oğuz, H Kağan; Bozkurt, Ayhan; Köymen, Hayrettin; Atalar, Abdullah

    2012-06-01

    Capacitive micromachined ultrasonic transducers (CMUTs) have great potential to compete with piezoelectric transducers in high-power applications. As the output pressures increase, nonlinearity of CMUT must be reconsidered and optimization is required to reduce harmonic distortions. In this paper, we describe a design approach in which uncollapsed CMUT array elements are sized so as to operate at the maximum radiation impedance and have gap heights such that the generated electrostatic force can sustain a plate displacement with full swing at the given drive amplitude. The proposed design enables high output pressures and low harmonic distortions at the output. An equivalent circuit model of the array is used that accurately simulates the uncollapsed mode of operation. The model facilities the design of CMUT parameters for high-pressure output, without the intensive need for computationally involved FEM tools. The optimized design requires a relatively thick plate compared with a conventional CMUT plate. Thus, we used a silicon wafer as the CMUT plate. The fabrication process involves an anodic bonding process for bonding the silicon plate with the glass substrate. To eliminate the bias voltage, which may cause charging problems, the CMUT array is driven with large continuous wave signals at half of the resonant frequency. The fabricated arrays are tested in an oil tank by applying a 125-V peak 5-cycle burst sinusoidal signal at 1.44 MHz. The applied voltage is increased until the plate is about to touch the bottom electrode to get the maximum peak displacement. The observed pressure is about 1.8 MPa with -28 dBc second harmonic at the surface of the array.

  15. Experimental design and construction of an enhanced solar battery charger

    OpenAIRE

    Faithpraise, Fina; Bassey, Donatus; Charles, Mfon; Osahon, Okoro; Udoh, Monday; Chatwin, Chris

    2016-01-01

    A Solar Battery Charger circuit is designed, built and tested. It acts as a control circuit to monitor and regulate the process of charging several batteries ranging from 4 volts to 12 volts, using a photovoltaic (PV) solar panel as the input source for the battery charging process. The circuit is economical and can be easily constructed from discrete electronic components. The circuit operation is based on matching the solar panel terminal load voltage to the input terminal of the charging c...

  16. Optimal experimental designs for dose–response studies with continuous endpoints

    OpenAIRE

    Holland-Letz, Tim; Kopp-Schneider, Annette

    2014-01-01

    In most areas of clinical and preclinical research, the required sample size determines the costs and effort for any project, and thus, optimizing sample size is of primary importance. An experimental design of dose–response studies is determined by the number and choice of dose levels as well as the allocation of sample size to each level. The experimental design of toxicological studies tends to be motivated by convention. Statistical optimal design theory, however, allows the setting of ex...

  17. Statistical Approaches in Analysis of Variance: from Random Arrangements to Latin Square Experimental Design

    OpenAIRE

    2009-01-01

    Background: The choices of experimental design as well as of statisticalanalysis are of huge importance in field experiments. These are necessary tobe correctly in order to obtain the best possible precision of the results. Therandom arrangements, randomized blocks and Latin square designs werereviewed and analyzed from the statistical perspective of error analysis.Material and Method: Random arrangements, randomized block and Latinsquares experimental designs were used as field experiments. ...

  18. Experimental burn plot trial in the Kruger National Park: history, experimental design and suggestions for data analysis

    Directory of Open Access Journals (Sweden)

    R. Biggs

    2003-12-01

    Full Text Available The experimental burn plot (EBP trial initiated in 1954 is one of few ongoing long-termfire ecology research projects in Africa. The trial aims to assess the impacts of differentfire regimes in the Kruger National Park. Recent studies on the EBPs have raised questions as to the experimental design of the trial, and the appropriate model specificationwhen analysing data. Archival documentation reveals that the original design was modified on several occasions, related to changes in the park's fire policy. These modifications include the addition of extra plots, subdivision of plots and changes in treatmentsover time, and have resulted in a design which is only partially randomised. The representativity of the trial plots has been questioned on account of their relatively small size,the concentration of herbivores on especially the frequently burnt plots, and soil variation between plots. It is suggested that these factors be included as covariates inexplanatory models or that certain plots be excluded from data analysis based on resultsof independent studies of these factors. Suggestions are provided for the specificationof the experimental design when analysing data using Analysis of Variance. It is concluded that there is no practical alternative to treating the trial as a fully randomisedcomplete block design.

  19. Gladstone-Dale constant for CF4. [experimental design

    Science.gov (United States)

    Burner, A. W., Jr.; Goad, W. K.

    1980-01-01

    The Gladstone-Dale constant, which relates the refractive index to density, was measured for CF4 by counting fringes of a two-beam interferometer, one beam of which passes through a cell containing the test gas. The experimental approach and sources of systematic and imprecision errors are discussed. The constant for CF4 was measured at several wavelengths in the visible region of the spectrum. A value of 0.122 cu cm/g with an uncertainty of plus or minus 0.001 cu cm/g was determined for use in the visible region. A procedure for noting the departure of the gas density from the ideal-gas law is discussed.

  20. Taguchi Experimental Design for Cleaning PWAs with Ball Grid Arrays

    Science.gov (United States)

    Bonner, J. K.; Mehta, A.; Walton, S.

    1997-01-01

    Ball grid arrays (BGAs), and other area array packages, are becoming more prominent as a way to increase component pin count while avoiding the manufacturing difficulties inherent in processing quad flat packs (QFPs)...Cleaning printed wiring assemblies (PWAs) with BGA components mounted on the surface is problematic...Currently, a low flash point semi-aqueous material, in conjunction with a batch cleaning unit, is being used to clean PWAs. The approach taken at JPL was to investigate the use of (1) semi-aqueous materials having a high flash point and (2) aqueous cleaning involving a saponifier.

  1. Mapping a landscape of learning design: Identifying key trends in current practice at the Open University

    OpenAIRE

    Cross, Simon; Conole, Grainne; Clark, Paul; Brasher, Andrew; Weller, Martin

    2008-01-01

    The object of this paper is to present some early analysis of interview and focus group data about how existing teacher educators at The Open University (UK) approach, understand, and deploy learning design and the additional support and tools they would find helpful. This represents a component of a broader institutional project that seeks to develop a learning design tool for the support and promotion of learning design and to better define the current landscape of learning design across th...

  2. Experimental design and quality assurance: in situ fluorescence instrumentation

    Science.gov (United States)

    Conmy, Robyn N.; Del Castillo, Carlos E.; Downing, Bryan D.; Chen, Robert F.

    2014-01-01

    Both instrument design and capabilities of fluorescence spectroscopy have greatly advanced over the last several decades. Advancements include solid-state excitation sources, integration of fiber optic technology, highly sensitive multichannel detectors, rapid-scan monochromators, sensitive spectral correction techniques, and improve data manipulation software (Christian et al., 1981, Lochmuller and Saavedra, 1986; Cabniss and Shuman, 1987; Lakowicz, 2006; Hudson et al., 2007). The cumulative effect of these improvements have pushed the limits and expanded the application of fluorescence techniques to numerous scientific research fields. One of the more powerful advancements is the ability to obtain in situ fluorescence measurements of natural waters (Moore, 1994). The development of submersible fluorescence instruments has been made possible by component miniaturization and power reduction including advances in light sources technologies (light-emitting diodes, xenon lamps, ultraviolet [UV] lasers) and the compatible integration of new optical instruments with various sampling platforms (Twardowski et at., 2005 and references therein). The development of robust field sensors skirt the need for cumbersome and or time-consuming filtration techniques, the potential artifacts associated with sample storage, and coarse sampling designs by increasing spatiotemporal resolution (Chen, 1999; Robinson and Glenn, 1999). The ability to obtain rapid, high-quality, highly sensitive measurements over steep gradients has revolutionized investigations of dissolved organic matter (DOM) optical properties, thereby enabling researchers to address novel biogeochemical questions regarding colored or chromophoric DOM (CDOM). This chapter is dedicated to the origin, design, calibration, and use of in situ field fluorometers. It will serve as a review of considerations to be accounted for during the operation of fluorescence field sensors and call attention to areas of concern when making

  3. Design of the power supply system for the plasma current modulation on J-TEXT tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, M.; Shao, J.; Ma, S.X., E-mail: mashaoxiang@hust.edu.cn; Liang, X.; Yu, K.X.; Pan, Y.

    2016-10-15

    Highlights: • A modification scheme of heating field power supply system for plasma current modulation. • High-power fast control power supply with multilevel cascade circuit. • Restraining circulating current with coupled inductors in cyclic symmetric structure. - Abstract: In order to further study the influence of current modulation parameters on suppressing tearing instability, the plasma current should be modulated in a wider range. So a modification scheme is designed to improve the performance of ohmic heating power supply system on J-TEXT tokamak. A multilevel cascade circuit with carrier phase-shifted PWM technique has been proposed. Coupled inductors are connected in the form of cyclic symmetry to restrain the circulating current caused by multiple paralleled branches. The simulation proves this proposed current modulation power supply system matches output requirement and achieves good current sharing effect. Finally, a prototype is designed, and the experiment results can verify the correctness of the simulation model well.

  4. Physics Design of Criticality Assembly in Experimental Research About Criticality Safety in Spent Fuel Dissolver

    Institute of Scientific and Technical Information of China (English)

    ZHOU; Qi

    2012-01-01

    <正>In order to meet the experimental demand of criticality safety research in the spent fuel dissolver, we need to design a suitable criticality assembly. The key problem of the design work is the core design because there are many limits for it such as the number of fuel rods loaded, fissile materials existed in the solution, reactivity control, core size and etc.

  5. Manufacturing cereal bars with high nutritional value through experimental design

    Directory of Open Access Journals (Sweden)

    Roberta Covino

    2015-01-01

    Full Text Available Organizations responsible for public health throughout the world have been increasingly worrying about how to feed populations encouraging a nutritious and balanced diet in order to decrease the occurrence of chronic diseases, which are constantly related to an inadequate diet. Still, due to matters of modern lifestyle consumers are increasingly seeking convenient products. This being so, cereal bars have been an option when the matter is low calorie fast food which is also source of fiber. This study aimed at developing a cereal bar with high dietary fiber, iron, vitamins A and vitamin E, in order to easily enable adult population achieve the daily recommendation for such nutrients. Eight formulations plus the focal point were conducted through experimental planning; sensory analysis with 110 tasters for each block and texture. Afterwards, we conducted centesimal analysis for all three formulations presenting the best sensory results. After statistical analysis and comparison to the means for products available in the market, it was possible to conclude that the product developed presented great acceptance and fiber level more than twice as much as the means for commercial products.

  6. A projection method for under determined optimal experimental designs

    KAUST Repository

    Long, Quan

    2014-01-09

    A new implementation, based on the Laplace approximation, was developed in (Long, Scavino, Tempone, & Wang 2013) to accelerate the estimation of the post–experimental expected information gains in the model parameters and predictive quantities of interest. A closed–form approximation of the inner integral and the order of the corresponding dominant error term were obtained in the cases where the parameters are determined by the experiment. In this work, we extend that method to the general cases where the model parameters could not be determined completely by the data from the proposed experiments. We carry out the Laplace approximations in the directions orthogonal to the null space of the corresponding Jacobian matrix, so that the information gain (Kullback–Leibler divergence) can be reduced to an integration against the marginal density of the transformed parameters which are not determined by the experiments. Furthermore, the expected information gain can be approximated by an integration over the prior, where the integrand is a function of the projected posterior covariance matrix. To deal with the issue of dimensionality in a complex problem, we use Monte Carlo sampling or sparse quadratures for the integration over the prior probability density function, depending on the regularity of the integrand function. We demonstrate the accuracy, efficiency and robustness of the proposed method via several nonlinear under determined numerical examples.

  7. A modified experimental hut design for studying responses of disease-transmitting mosquitoes to indoor interventions: the Ifakara experimental huts.

    Directory of Open Access Journals (Sweden)

    Fredros O Okumu

    Full Text Available Differences between individual human houses can confound results of studies aimed at evaluating indoor vector control interventions such as insecticide treated nets (ITNs and indoor residual insecticide spraying (IRS. Specially designed and standardised experimental huts have historically provided a solution to this challenge, with an added advantage that they can be fitted with special interception traps to sample entering or exiting mosquitoes. However, many of these experimental hut designs have a number of limitations, for example: 1 inability to sample mosquitoes on all sides of huts, 2 increased likelihood of live mosquitoes flying out of the huts, leaving mainly dead ones, 3 difficulties of cleaning the huts when a new insecticide is to be tested, and 4 the generally small size of the experimental huts, which can misrepresent actual local house sizes or airflow dynamics in the local houses. Here, we describe a modified experimental hut design - The Ifakara Experimental Huts- and explain how these huts can be used to more realistically monitor behavioural and physiological responses of wild, free-flying disease-transmitting mosquitoes, including the African malaria vectors of the species complexes Anopheles gambiae and Anopheles funestus, to indoor vector control-technologies including ITNs and IRS. Important characteristics of the Ifakara experimental huts include: 1 interception traps fitted onto eave spaces and windows, 2 use of eave baffles (panels that direct mosquito movement to control exit of live mosquitoes through the eave spaces, 3 use of replaceable wall panels and ceilings, which allow safe insecticide disposal and reuse of the huts to test different insecticides in successive periods, 4 the kit format of the huts allowing portability and 5 an improved suite of entomological procedures to maximise data quality.

  8. Design, Assembly, and Commissioning of a Cryogenic DC Current Transformer Designed for Measuring Currents of up to 80 kA

    CERN Document Server

    Montenero, G; Bottura, L; Arpaia, P

    2015-01-01

    A new cryogenic dc current transformer (Cryo-DCCT) has recently been designed and assembled at CERN. The device, whose design is based on that of a high-accuracy 600 A market solution suitable for room temperature applications, is optimized for measuring currents of up to 80 kA and for operation at 4.2 K. The CryoDCCT has been conceived with the objective of preserving the metrological performance of the original commercial device in the new extended range of operation. For reducing the effect of interfering magnetic fields arising from test conditions, it incorporates ferromagnetic and MgB2 superconducting shields. In this paper, the design of the CryoDCCT and the results of the commissioning of the device at CERN are reported. The effectiveness of the current transducer is analysed and discussed. This new device will be used for measuring the secondary current of a 80 kA superconducting transformer feeding a sample of NbSn3 cable at the Facility for Research on Superconducting Cables (FRESCA) at CERN.

  9. A passive exoskeleton with artificial tendons: design and experimental evaluation.

    Science.gov (United States)

    van Dijk, Wietse; van der Kooij, Herman; Hekman, Edsko

    2011-01-01

    We developed a passive exoskeleton that was designed to minimize joint work during walking. The exoskeleton makes use of passive structures, called artificial tendons, acting in parallel with the leg. Artificial tendons are elastic elements that are able to store and redistribute energy over the human leg joints. The elastic characteristics of the tendons have been optimized to minimize the mechanical work of the human leg joints. In simulation the maximal reduction was 40 percent. The performance of the exoskeleton was evaluated in an experiment in which nine subjects participated. Energy expenditure and muscle activation were measured during three conditions: Normal walking, walking with the exoskeleton without artificial tendons, and walking with the exoskeleton with the artificial tendons. Normal walking was the most energy efficient. While walking with the exoskeleton, the artificial tendons only resulted in a negligibly small decrease in energy expenditure.

  10. Expanded microchannel heat exchanger: design, fabrication and preliminary experimental test

    CERN Document Server

    Denkenberger, David C; Pearce, Joshua M; Zhai, John; 10.1177/0957650912442781

    2012-01-01

    This paper first reviews non-traditional heat exchanger geometry, laser welding, practical issues with microchannel heat exchangers, and high effectiveness heat exchangers. Existing microchannel heat exchangers have low material costs, but high manufacturing costs. This paper presents a new expanded microchannel heat exchanger design and accompanying continuous manufacturing technique for potential low-cost production. Polymer heat exchangers have the potential for high effectiveness. The paper discusses one possible joining method - a new type of laser welding named "forward conduction welding," used to fabricate the prototype. The expanded heat exchanger has the potential to have counter-flow, cross-flow, or parallel-flow configurations, be used for all types of fluids, and be made of polymers, metals, or polymer-ceramic precursors. The cost and ineffectiveness reduction may be an order of magnitude or more, saving a large fraction of primary energy. The measured effectiveness of the prototype with 28 micro...

  11. Design,fabrication and experimental research for an electrohydrodynamic micropump

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    This paper presented a novel electrohydrodynamic (EHD) micropump based on MEMS technology. The working mechanisms and classification of EHD micropump were introduced. The fabrication process of EHD micropump was presented with the material selection,optimal design of microelectrode and assembly process. Static pressure experiments and flow experiments were carried out using different fluid and the channel depth. The results indicated that the micropump could achieve a maximum static pressure head of 268 Pa at an applied voltage of 90 V. The maximum flow rate of the micropump-driven fluid could reach 106 μL/min. This paper analyzed the future of combining micropump with heat pipe to deal with heat dissipation of high power electronic chips. The maximum heat dissipation capacity of 87 W/cm2 can be realized by vaporizing the micropump-driven liquid on vaporizing section of the heat pipe.

  12. Comparison of experimental and theoretical gain-current relations in GaInP quantum well lasers

    Energy Technology Data Exchange (ETDEWEB)

    Smowton, P.M.; Chow, W.W.; Blood, P.

    2000-01-10

    The authors compare the results of a microscopic laser theory with gain and recombination currents obtained from experimental spontaneous emission spectra. The calculated absorption spectrum is first matched to that measured on a laser, ensuring that the quasi-Fermi levels for the calculation and the experiment (spontaneous emission and gain) are directly related. This allows one to determine the inhomogeneous broadening in their experimental samples. The only other inputs to the theory are literature values of the bulk material parameter. The authors then estimate the non-radiative recombination current associated with the well and wave-guide core from a comparison of measured and calculated recombination currents.

  13. Constructing experimental designs for discrete-choice experiments: report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force.

    Science.gov (United States)

    Reed Johnson, F; Lancsar, Emily; Marshall, Deborah; Kilambi, Vikram; Mühlbacher, Axel; Regier, Dean A; Bresnahan, Brian W; Kanninen, Barbara; Bridges, John F P

    2013-01-01

    Stated-preference methods are a class of evaluation techniques for studying the preferences of patients and other stakeholders. While these methods span a variety of techniques, conjoint-analysis methods-and particularly discrete-choice experiments (DCEs)-have become the most frequently applied approach in health care in recent years. Experimental design is an important stage in the development of such methods, but establishing a consensus on standards is hampered by lack of understanding of available techniques and software. This report builds on the previous ISPOR Conjoint Analysis Task Force Report: Conjoint Analysis Applications in Health-A Checklist: A Report of the ISPOR Good Research Practices for Conjoint Analysis Task Force. This report aims to assist researchers specifically in evaluating alternative approaches to experimental design, a difficult and important element of successful DCEs. While this report does not endorse any specific approach, it does provide a guide for choosing an approach that is appropriate for a particular study. In particular, it provides an overview of the role of experimental designs for the successful implementation of the DCE approach in health care studies, and it provides researchers with an introduction to constructing experimental designs on the basis of study objectives and the statistical model researchers have selected for the study. The report outlines the theoretical requirements for designs that identify choice-model preference parameters and summarizes and compares a number of available approaches for constructing experimental designs. The task-force leadership group met via bimonthly teleconferences and in person at ISPOR meetings in the United States and Europe. An international group of experimental-design experts was consulted during this process to discuss existing approaches for experimental design and to review the task force's draft reports. In addition, ISPOR members contributed to developing a consensus

  14. Current Mooring Design in Partner WECs and Candidates for Preliminary Analysis

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Ferri, Francesco; Kofoed, Jens Peter

    This report is the combined report of Commercial Milestone "CM1: Design and Cost of Current Mooring Solutions of Partner WECs" and Milestone "M3: Mooring Solutions for Preliminary Analysis" of the EUDP project "Mooring Solutions for Large Wave Energy Converters". The report covers a description...... of the current mooring design of the partner Wave Energy Converter (WEC) developers in the project, together with a preliminary cost estimate of the systems....

  15. Using experimental designs for modelling of intermittent air filtration process

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Identification of the optimal operating conditions and evaluation of their robustness are critical issues for industrial processes.A standard procedure,for modelling a laboratory-scale wire-to-cylinder electrostatic precipitator and for guiding the research of the set point,is presented.The procedure consists of formulating a set of recommendations regarding the choice of parameter values for electrostatic precipitation.The experiments were carried out on a laboratory cylindrical precipitator,built by one of the authors,with samples of wood particles.The parameters considered are the applied high voltage U,the air flow F,and the quantity of dust in air m.Several"one-factor-at-a-time"followed by factorial composite design experiments were performed,based on the following three-step strategy:1)Identify the domain of variation of the variables;2)Determine the mathematical model of the process outcome:3)Validation of the mathematical model and optimisation of the process.

  16. New experimental model design for VAPEX process experiments

    Energy Technology Data Exchange (ETDEWEB)

    Yazdani, J.A.; Maini, B.B. [Calgary Univ., AB (Canada)

    2004-07-01

    The vast resources of heavy oil and bitumen deposits in Venezuela and Canada have become targets for finding less costly and more effective hydrocarbon recovery methods. Solvent extraction of heavy deposits is an attractive option that is gaining much attention as an in-situ recovery method. Vapour extraction (VAPEX) is analogous to the steam assisted gravity drainage (SAGD) process for the recovery of heavy oil and tar sand reservoirs. However, in VAPEX, vaporized solvents are used instead of high temperature steam and the viscosity of the oil is reduced in situ. VAPEX is particularly suited for formations that are thin and where heat losses are unavoidable. It is also well suited in the presence of overlying gas caps; bottom water aquifers; low thermal conductivity; high water saturation; clay swelling; and, formation damage. Most modelling studies use rectangular shaped models, but these have limitations at high reservoir pressures. This study presents a new design of physical models that overcomes these limitations. The annular space between two cylindrical pipes is used for developing slice-type and sand-filled models. This newly developed model is more compatible with higher pressures. This paper compares results of VAPEX experiments using the cylindrical models and the rectangular models. The stabilized drainage rates from the newly developed cylindrical models are in very good agreement with those from the rectangular models. 16 refs., 3 tabs., 11 figs.

  17. Rational Design of Transcranial Current Stimulation (TCS through Mechanistic Insights into Cortical Network Dynamics

    Directory of Open Access Journals (Sweden)

    Flavio eFrohlich

    2013-11-01

    Full Text Available Transcranial current stimulation (TCS is a promising method of non-invasive brain stimulation to modulate cortical network dynamics. Preliminary studies have demonstrated the ability of TCS to enhance cognition and reduce symptoms in both neurological and psychiatric illnesses. Despite the encouraging results of these studies, the mechanisms by which TCS and endogenous network dynamics interact remain poorly understood. Here, we propose that the development of the next generation of TCS paradigms with increased efficacy requires such mechanistic understanding of how weak electric fields imposed by TCS interact with the nonlinear dynamics of large-scale cortical networks. We highlight key recent advances in the study of the interaction dynamics between TCS and cortical network activity. In particular, we demonstrate the opportunities provided by an interdisciplinary approach that bridges neurobiology and electrical engineering. We discuss the use of (1 hybrid biological-electronic experimental approaches to disentangle feedback interactions, (2 large-scale computer simulations for the study of weak global perturbations imposed by TCS, and (3 optogenetic manipulations informed by dynamics systems theory to probe network dynamics. Together, we here provide the foundation for the use of rational design for the development of the next generation of TCS neurotherapeutics.

  18. Single Component Sorption-Desorption Test Experimental Design Approach Discussions

    Energy Technology Data Exchange (ETDEWEB)

    Phil WInston

    2011-09-01

    A task was identified within the fission-product-transport work package to develop a path forward for doing testing to determine behavior of volatile fission products behavior and to engage members of the NGNP community to advise and dissent on the approach. The following document is a summary of the discussions and the specific approaches suggested for components of the testing. Included in the summary isare the minutes of the conference call that was held with INL and external interested parties to elicit comments on the approaches brought forward by the INL participants. The conclusion was that an initial non-radioactive, single component test will be useful to establish the limits of currently available chemical detection methods, and to evaluated source-dispersion uniformity. In parallel, development of a real-time low-concentration monitoring method is believed to be useful in detecting rapid dispersion as well as desorption phenomena. Ultimately, the test cycle is expected to progress to the use of radio-traced species, simply because this method will allow the lowest possible detection limits. The consensus of the conference call was that there is no need for an in-core test because the duct and heat exchanger surfaces that will be the sorption target will be outside the main neutron flux and will not be affected by irradiation. Participants in the discussion and contributors to the INL approach were Jeffrey Berg, Pattrick Calderoni, Gary Groenewold, Paul Humrickhouse, Brad Merrill, and Phil Winston. Participants from outside the INL included David Hanson of General Atomics, Todd Allen, Tyler Gerczak, and Izabela Szlufarska of the University of Wisconsin, Gary Was, of the University of Michigan, Sudarshan Loyalka and Tushar Ghosh of the University of Missouri, and Robert Morris of Oak Ridge National Laboratory.

  19. Design and experimental research on cantilever accelerometer based on fiber Bragg grating

    Science.gov (United States)

    Xiang, Longhai; Jiang, Qi; Li, Yibin; Song, Rui

    2016-06-01

    Currently, an acceleration sensor based on fiber Bragg grating (FBG) has been widely used. A cantilever FBG accelerometer is designed. The simulation of this structure was implemented by finite element software (ANSYS) to analyze its sensing performance parameters. And then the optimized structure was produced and calibration experiments were conducted. On the basis of simulation, optical fiber is embedded in the inner tank of the vibrating mass, and Bragg grating is suspended above the cantilever structure, which can effectively avoid the phenomenon of center wavelength chirp or broadening, and greatly improve the sensitivity of the sensor. The experimental results show that the FBG accelerometer exhibits a sensitivity of 75 pm/(m/s2) (100 Hz) and dynamic range of 60 dB. Its linearity error is <2.31% and repeatability error is <2.76%. And the resonant frequency is ˜125 Hz. The simulation results match the experimental results to demonstrate the good performance of FBG accelerometer, which is expected to be used in the actual project.

  20. Design and Experimental Verification of Deployable/Inflatable Ultra-Lightweight Structures

    Science.gov (United States)

    Pai, P. Frank

    2004-01-01

    Because launch cost of a space structural system is often proportional to the launch volume and mass and there is no significant gravity in space, NASA's space exploration programs and various science missions have stimulated extensive use of ultra-lightweight deployable/inflatable structures. These structures are named here as Highly Flexible Structures (HFSs) because they are designed to undergo large displacements, rotations, and/or buckling without plastic deformation under normal operation conditions. Except recent applications to space structural systems, HFSs have been used in many mechanical systems, civil structures, aerospace vehicles, home appliances, and medical devices to satisfy space limitations, provide special mechanisms, and/or reduce structural weight. The extensive use of HFSs in today's structural engineering reveals the need of a design and analysis software and a database system with design guidelines for practicing engineers to perform computer-aided design and rapid prototyping of HFSs. Also to prepare engineering students for future structural engineering requires a new and easy-to- understand method of presenting the complex mathematics of the modeling and analysis of HFSs. However, because of the high flexibility of HFSs, many unique challenging problems in the modeling, design and analysis of HFSs need to be studied. The current state of research on HFSs needs advances in the following areas: (1) modeling of large rotations using appropriate strain measures, (2) modeling of cross-section warpings of structures, (3) how to account for both large rotations and cross- section warpings in 2D (two-dimensional) and 1D structural theories, (4) modeling of thickness thinning of membranes due to inflation pressure, pretension, and temperature change, (5) prediction of inflated shapes and wrinkles of inflatable structures, (6) development of efficient numerical methods for nonlinear static and dynamic analyses, and (7) filling the gap between

  1. Design and experimental tests of free electron laser wire scanners

    Science.gov (United States)

    Orlandi, G. L.; Heimgartner, P.; Ischebeck, R.; Loch, C. Ozkan; Trovati, S.; Valitutti, P.; Schlott, V.; Ferianis, M.; Penco, G.

    2016-09-01

    SwissFEL is a x-rays free electron laser (FEL) driven by a 5.8 GeV linac under construction at Paul Scherrer Institut. In SwissFEL, wire scanners (WSCs) will be complementary to view-screens for emittance measurements and routinely used to monitor the transverse profile of the electron beam during FEL operations. The SwissFEL WSC is composed of an in-vacuum beam-probe—motorized by a stepper motor—and an out-vacuum pick-up of the wire signal. The mechanical stability of the WSC in-vacuum hardware has been characterized on a test bench. In particular, the motor induced vibrations of the wire have been measured and mapped for different motor speeds. Electron-beam tests of the entire WSC setup together with different wire materials have been carried out at the 250 MeV SwissFEL Injector Test Facility (SITF, Paul Scherrer Institut, CH) and at FERMI (Elettra-Sincrotrone Trieste, Italy). In particular, a comparative study of the relative measurement accuracy and the radiation-dose release of Al (99 )∶Si (1 ) and tungsten (W) wires has been carried out. On the basis of the outcome of the bench and electron-beam tests, the SwissFEL WSC can be qualified as a high resolution and machine-saving diagnostic tool in consideration of the mechanical stability of the scanning wire at the micrometer level and the choice of the wire material ensuring a drastic reduction of the radiation-dose release with respect to conventional metallic wires. The main aspects of the design, laboratory characterization and electron beam tests of the SwissFEL WSCs are presented.

  2. STRONG LENS TIME DELAY CHALLENGE. I. EXPERIMENTAL DESIGN

    Energy Technology Data Exchange (ETDEWEB)

    Dobler, Gregory [Kavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, CA 93106 (United States); Fassnacht, Christopher D.; Rumbaugh, Nicholas [Department of Physics, University of California, 1 Shields Avenue, Davis, CA 95616 (United States); Treu, Tommaso; Liao, Kai [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Marshall, Phil [Kavli Institute for Particle Astrophysics and Cosmology, P.O. Box 20450, MS29, Stanford, CA 94309 (United States); Hojjati, Alireza [Department of Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, B.C. V6T 1Z1 (Canada); Linder, Eric, E-mail: tt@astro.ucla.edu [Lawrence Berkeley National Laboratory and University of California, Berkeley, CA 94720 (United States)

    2015-02-01

    The time delays between point-like images in gravitational lens systems can be used to measure cosmological parameters. The number of lenses with measured time delays is growing rapidly; the upcoming Large Synoptic Survey Telescope (LSST) will monitor ∼10{sup 3} strongly lensed quasars. In an effort to assess the present capabilities of the community, to accurately measure the time delays, and to provide input to dedicated monitoring campaigns and future LSST cosmology feasibility studies, we have invited the community to take part in a ''Time Delay Challenge'' (TDC). The challenge is organized as a set of ''ladders'', each containing a group of simulated data sets to be analyzed blindly by participating teams. Each rung on a ladder consists of a set of realistic mock observed lensed quasar light curves, with the rungs' data sets increasing in complexity and realism. The initial challenge described here has two ladders, TDC0 and TDC1. TDC0 has a small number of data sets, and is designed to be used as a practice set by the participating teams. The (non-mandatory) deadline for completion of TDC0 was the TDC1 launch date, 2013 December 1. The TDC1 deadline was 2014 July 1. Here we give an overview of the challenge, we introduce a set of metrics that will be used to quantify the goodness of fit, efficiency, precision, and accuracy of the algorithms, and we present the results of TDC0. Thirteen teams participated in TDC0 using 47 different methods. Seven of those teams qualified for TDC1, which is described in the companion paper.

  3. Batch phenol biodegradation study and application of factorial experimental design

    Directory of Open Access Journals (Sweden)

    A. Hellal

    2010-01-01

    Full Text Available A bacterium, Pseudomonas aeruginosa (ATTC27853, was investigated for its ability to grow and to degrade phenol as solecarbon source, in aerobic batch culture. The parameters which affect the substrate biodegradation such as the adaptation ofbacteria to phenol, the temperature, and the nature of the bacteria were investigated. The results show that for a range oftemperature of 30 to 40°C, the best degradation of phenol for a concentration of 100mg/l was observed at 30°C. The regenerationof the bacterium which allows the reactivation of its enzymatic activity, shows that the degradation of 100 mg/ l ofsubstrate at 30° C required approximately 50 hours with revivified bacteria, while it only starts after 72 hours for those norevivified. Adapted to increasing concentrations, allows the bacteria to degrade a substrate concentration of about 400mg/l in less than 350 hours.A second part was consisted in the determination of a substrate degradation model using the factorial experiment design,as a function of temperature (30-40°C and of the size of the inoculums (260.88 - 521.76mg/ l. The results were analyzedstatistically using the Student’s t-test, analysis of variance, and F-test. The value of R2 (0.99872 and adjusted R2 (0.9962close to 1.0, verifies the good correlation between the observed and the predicted values, and provides the excellent relationshipbetween the independent variables (factors and the response (the time of the phenol degradation. F-value found above200, indicates that the considered model is statistically significant.

  4. Novel Wien Bridge Oscillator Design Using Functional Block Structure with Current Conveyors

    Directory of Open Access Journals (Sweden)

    Pavel Brandstetter

    2012-01-01

    Full Text Available The purpose of this paper is to generally present possibilities of the current conveyor use in the well-known active electronic circuits. Current conveyors are able to substitute all known active elements. This claim is supported by the fact, that four basic functional block structures can be realized by use of current conveyors - voltage-controlled voltage source, voltage-controlled current source, current-controlled current source and current-controlled voltage source. The paper presents particular example of use of functional block structure with current conveyors in Wien bridge oscillator, where it successfully substitutes operational amplifier on the place of active element. Both theoretical formulae and design description are given. Finally, OrCAD PSpice simulation results are presented.

  5. Optimal design and experimental analysis of a magnetorheological valve system for the vehicle lifter used in maintenance

    Science.gov (United States)

    Shin, Sang-Un; Lee, Tae-Hoon; Cha, Seung-Woo; Choi, Ji-Young; Choi, Seung-Bok

    2017-04-01

    An accurate position control is demanded in the current hydraulic lifter used for vehicle maintenance. This work presents a new type of vehicle lifter for precision position control using a magnetorheological valve system. In the first step, the principal design parameters such as gap size of oil passage, length and depth of coil part, and distance coil part from the end of valve are considered to achieve the objective function for getting the highest position accuracy under current input constraint. After determining the optimized design values, the field-dependent pressure drops of the optimized valve system are experimentally evaluated and compared to those obtained from the initial design. Subsequently, the position of the vehicle lifter is controlled by change of pressure drop using a simple PID controller. It is demonstrated that the proposed vehicle lifter can be effectively applied to vehicle service center for more accurate tasks under proper height.

  6. Design and Status of the Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII): An Interferometer at the Edge of Space

    Science.gov (United States)

    Rinehart, Stephen A.; Barclay, Richard B.; Barry, R. K.; Benford, D. J.; Calhoun, P. C.; Fixsen, D. J.; Gorman, E. T.; Jackson, M. L.; Jhabvala, C. A.; Leisawitz, D. T.; Maher, S. F.; Mentzell, J. E.; Mundy, L. G.; Rizzo, M. J.; Silverberg, R. F.; Staguhn, J. G.

    2012-01-01

    The Balloon Experimental Twin Telescope for Infrared Interferometry (BETTII) is an 8-meter baseline far-infraredinterferometer designed to fly on a high altitude balloon. BETTII uses a double-Fourier Michelson interferometer tosimultaneously obtain spatial and spectral information on science targets; the long baseline permits subarcsecond angular resolution, a capability unmatched by other far-infrared facilities. Here, we present key aspects of the overall design of the mission and provide an overview of the current status of the project. We also discuss briefly the implications of this experiment for future space-based far-infrared interferometers.

  7. Design and Development of a Low-Cost Optical Current Sensor

    Directory of Open Access Journals (Sweden)

    Gaizka Durana

    2013-10-01

    Full Text Available In this paper we demonstrate the design of a low-cost optical current sensor. The sensor principle is the Faraday rotation of a light beam through a magneto-optical material, SF2, when a magnetic field is present. The prototype has a high sensitivity and a high linearity for currents ranging from 0 up to 800 A. The error of the optical fibre sensor is smaller than 1% for electric currents over 175 A.

  8. Design and development of a low-cost optical current sensor.

    Science.gov (United States)

    Zubia, Joseba; Casado, Luciano; Aldabaldetreku, Gotzon; Montero, Alfonso; Zubia, Eneko; Durana, Gaizka

    2013-10-10

    In this paper we demonstrate the design of a low-cost optical current sensor. The sensor principle is the Faraday rotation of a light beam through a magneto-optical material, SF2, when a magnetic field is present. The prototype has a high sensitivity and a high linearity for currents ranging from 0 up to 800 A. The error of the optical fibre sensor is smaller than 1% for electric currents over 175 A.

  9. Experimental analysis of oligonucleotide microarray design criteria to detect deletions by comparative genomic hybridization

    Directory of Open Access Journals (Sweden)

    Moerman Donald G

    2008-10-01

    Full Text Available Abstract Background Microarray comparative genomic hybridization (CGH is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is widely used to assess copy number variants in healthy individuals and copy number aberrations associated with various diseases, syndromes and disease susceptibility. In model organisms such as Caenorhabditis elegans (C. elegans the technique has been applied to detect mutations, primarily deletions, in strains of interest. Although various constraints on oligonucleotide properties have been suggested to minimize non-specific hybridization and improve the data quality, there have been few experimental validations for CGH experiments. For genomic regions where strict design filters would limit the coverage it would also be useful to quantify the expected loss in data quality associated with relaxed design criteria. Results We have quantified the effects of filtering various oligonucleotide properties by measuring the resolving power for detecting deletions in the human and C. elegans genomes using NimbleGen microarrays. Approximately twice as many oligonucleotides are typically required to be affected by a deletion in human DNA samples in order to achieve the same statistical confidence as one would observe for a deletion in C. elegans. Surprisingly, the ability to detect deletions strongly depends on the oligonucleotide 15-mer count, which is defined as the sum of the genomic frequency of all the constituent 15-mers within the oligonucleotide. A similarity level above 80% to non-target sequences over the length of the probe produces significant cross-hybridization. We recommend the use of a fairly large melting temperature window of up to 10°C, the elimination of repeat sequences, the elimination of homopolymers longer than 5 nucleotides, and a threshold of -1 kcal/mol on the oligonucleotide self-folding energy. We observed very little difference in data

  10. Current Approaches to the Assessment of Graphic Design in a Higher Education Context

    Science.gov (United States)

    Giloi, Susan; du Toit, Pieter

    2013-01-01

    This article provides an overview of the current trends in assessment practice within the field of graphic design. The demands placed on educators to apply sound assessment practice for Higher Education subjects is as intense in the field of graphic design as in any other. Forcing the assessment of creative visual work into existing assessment…

  11. New Residual Stress Mapping Tool Applied to Atlas Current Joint Design

    Science.gov (United States)

    2013-06-01

    use on the Atlas capacitor bank . This new design dramatically changes how the liner, glide planes and current joints of the system are formed. The...A redesigned cylindrical liner system has been implemented for use on the Atlas capacitor bank . This new design dramatically changes how the liner

  12. Current Approaches to the Assessment of Graphic Design in a Higher Education Context

    Science.gov (United States)

    Giloi, Susan; du Toit, Pieter

    2013-01-01

    This article provides an overview of the current trends in assessment practice within the field of graphic design. The demands placed on educators to apply sound assessment practice for Higher Education subjects is as intense in the field of graphic design as in any other. Forcing the assessment of creative visual work into existing assessment…

  13. Experimental Measurement of Asymmetric Fluctuations of Poloidal Magnetic Field in Damavand Tokomak at Different Plasma Currents

    Science.gov (United States)

    Moslehi-Fard, Mahmoud; Alinejad, Naser; Rasouli, Chapar; Sadigzadeh, Asghar

    2012-08-01

    Toroidal and Poloidal magnetic fields have an important effect on the tokomak topology. Damavand Tokomak is a small size tokomak characterized with k = 1.2, B t = 1T, R 0 = 36 cm, maximum plasma current is about 35 KA with a discharge time of 21 ms. In this experimental work, the variation of poloidal magnetic field on the torodial cross section is measured and analyzed. In order to measure the polodial magnetic field, 18 probes were installed on the edge of tokomak plasma with ∆θ = 18°, while a limiter was installed inside the torus. Plasma current, I p, induces a polodial magnetic field, B p, smaller than the torodial magnetic field B t. Magnetic lines B produced as a combination of B t and B p, are localized on the nested toroidal magnetic surfaces. The presence of polodial magnetic field is necessary for particles confinement. Mirnov oscillations are the fluctuations of polodial magnetic field, detected by magnetic probes. Disrupted instability in Tokomak typically starts with mirnov oscillations which appear as fluctuations of polodial magnetic field and is detected by magnetic probes. Minor disruptions inside the plasma can contain principal magnetic islands and their satellites can cause the annihilation of plasma confinement. Production of thin layer of turbulent magnetic field lines cause minor disruption. Magnetic limiter may cause the deformation of symmetric equilibrium configuration and chaotic magnetic islands reveal in plasma occurring in thin region of chaotic field lines close to their separatrix. The width of this chaotic layer in the right side of poloidal profile of Damavand Tokomak is smaller than the width in the left side profile because of Shafranov displacement. Ergodic region in the left side of profile develops a perturbation on the magnetic polodial field lines, B p, that are greater in magnitude than that in the right side, although the values of B p on the left side are smaller than that on the right side of the profile. The Left

  14. Experimental study of a high-current FEM with a broadband microwave system

    Energy Technology Data Exchange (ETDEWEB)

    Denisov, G.G.; Bratman, V.L.; Ginzburg, N.S. [Institute of Applied Physics, Nizhny Novgorod (Russian Federation)] [and others

    1995-12-31

    One of the main features of FELs and FEMs is the possibility of fast and wideband tuning of the resonant frequency of active media, which can be provided by changing the particle energy. For a frequency adjustable FEM-oscillator, a broadband microwave system, which is simply combined with an electron-optical FEM system and consists of an oversized waveguide and reflectors based on the microwave beams multiplication effect has been proposed and studied successfully in {open_quotes}cold{close_quotes} measurements. Here, the operating ability of a cavity, that includes some key elements of the broadband microwave system, was tested in the presence of an electron beam. To provide large particle oscillation velocities in a moderate undulator field and the presence of a guide magnetic field, the FEM operating regime of double resonance was chosen. In this regime the cyclotron as well as undulator resonance conditions were satisfied. The FEM-oscillator was investigated experimentally on a high-current accelerator {open_quotes}Sinus-6{close_quotes} that forms an electron beam with particle energy 500keV and pulse duration 25ns. The aperture with a diameter 2.5mm at the center of the anode allows to pass through only the central fraction of the electron beam with a current about 100A and a small spread of longitudinal velocities of the particles. Operating transverse velocity was pumped into the electron beam in the pulse plane undulator of a 2.4cm period. The cavity with a frequency near 45GHz consists of a square waveguide and two reflectors. The broadband up-stream reflector based on the multiplication effect had the power reflectivity coefficient more than 90% in the frequency band 10% for the H{sup 10} wave of the square waveguide with the maximum about 100% at a frequency 45GHz. The down-stream narrow-band Bragg reflector had the power reflection coefficient approximately 80% in the frequency band of 4% near 45GHz for the operating mode.

  15. Delineamento experimental e tamanho de amostra para alface cultivada em hidroponia Experimental design and sample size for hydroponic lettuce crop

    Directory of Open Access Journals (Sweden)

    Valéria Schimitz Marodim

    2000-10-01

    Full Text Available Este estudo visa a estabelecer o delineamento experimental e o tamanho de amostra para a cultura da alface (Lactuca sativa em hidroponia, pelo sistema NFT (Nutrient film technique. O experimento foi conduzido no Laboratório de Cultivos Sem Solo/Hidroponia, no Departamento de Fitotecnia da Universidade Federal de Santa Maria e baseou-se em dados de massa de plantas. Os resultados obtidos mostraram que, usando estrutura de cultivo de alface em hidroponia sobre bancadas de fibrocimento com seis canais, o delineamento experimental adequado é blocos ao acaso se a unidade experimental for constituída de faixas transversais aos canais das bancadas, e deve ser inteiramente casualizado se a bancada for a unidade experimental; para a variável massa de plantas, o tamanho da amostra é de 40 plantas para uma semi-amplitude do intervalo de confiança em percentagem da média (d igual a 5% e de 7 plantas para um d igual a 20%.This study was carried out to establish the experimental design and sample size for hydroponic lettuce (Lactuca sativa crop under nutrient film technique. The experiment was conducted in the Laboratory of Hydroponic Crops of the Horticulture Department of the Federal University of Santa Maria. The evaluated traits were plant weight. Under hydroponic conditions on concrete bench with six ducts, the most indicated experimental design for lettuce is randomised blocks for duct transversal plots or completely randomised for bench plot. The sample size for plant weight should be 40 and 7 plants, respectively, for a confidence interval of mean percentage (d equal to 5% and 20%.

  16. Design, construction and testing of a radon experimental chamber; Diseno, construccion y pruebas de una camara experimental de radon

    Energy Technology Data Exchange (ETDEWEB)

    Chavez B, A.; Balcazar G, M

    1991-10-15

    To carry out studies on the radon behavior under controlled and stable conditions it was designed and constructed a system that consists of two parts: a container of mineral rich in Uranium and an experimentation chamber with radon united one to the other one by a step valve. The container of uranium mineral approximately contains 800 gr of uranium with a law of 0.28%; the radon gas emanated by the mineral is contained tightly by the container. When the valve opens up the radon gas it spreads to the radon experimental chamber; this contains 3 accesses that allow to install different types of detectors. The versatility of the system is exemplified with two experiments: 1. With the radon experimental chamber and an associated spectroscopic system, the radon and two of its decay products are identified. 2. The design of the system allows to couple the mineral container to other experimental geometries to demonstrate this fact it was coupled and proved a new automatic exchanger system of passive detectors of radon. The results of the new automatic exchanger system when it leave to flow the radon freely among the container and the automatic exchanger through a plastic membrane of 15 m. are shown. (Author)

  17. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    NARCIS (Netherlands)

    Clark, G.; Kosoris, J.; Nguyen Hong, L.; Crul, M.

    2009-01-01

    The Design for Sustainability (D4S) concept outlines methodologies for making sustainable improvements (social, economic and environmental) to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includ

  18. Design of the plasma grid for a short pulse negative ion source experimental setup at HUST

    Science.gov (United States)

    Zuo, C.; Li, D.; Chen, D.; Zhao, P.; Xu, Q.; Liao, Z.

    2017-08-01

    An experimental setup of a radio frequency (RF) driven negative hydrogen ion source has been developed at Huazhong University of Science and Technology (HUST). The setup without cesium oven and an extraction system had been completed and the plasma was ignited in the driver successfully in 2014. An extraction system with small area (5540 mm2) for short pulse (˜ 4 s) was designed to extract the negative hydrogen ions. Generally, the plasma grid temperature is controlled to reach 150 °C by the cooling channels inside the grid. But another method that we could use the PG current to raise the temperature is being considered only for the short pulse condition. An experiment was introduced to prove the feasibility of this method. A magnetic field produced by current flowing through the plasma grid is required to reduce the electron temperature and suppress the co-extraction electrons. The filter field homogeneity has been studied in detail by finite element method. There have been significant improvements regarding the field homogeneity by means of the grid geometry optimization.

  19. Frequency-Dependent Streaming Potential of Porous Media—Part 1: Experimental Approaches and Apparatus Design

    Directory of Open Access Journals (Sweden)

    P. W. J. Glover

    2012-01-01

    Full Text Available Electrokinetic phenomena link fluid flow and electrical flow in porous and fractured media such that a hydraulic flow will generate an electrical current and vice versa. Such a link is likely to be extremely useful, especially in the development of the electroseismic method. However, surprisingly few experimental measurements have been carried out, particularly as a function of frequency because of their difficulty. Here we have considered six different approaches to make laboratory determinations of the frequency-dependent streaming potential coefficient. In each case, we have analyzed the mechanical, electrical, and other technical difficulties involved in each method. We conclude that the electromagnetic drive is currently the only approach that is practicable, while the piezoelectric drive may be useful for low permeability samples and at specified high frequencies. We have used the electro-magnetic drive approach to design, build, and test an apparatus for measuring the streaming potential coefficient of unconsolidated and disaggregated samples such as sands, gravels, and soils with a diameter of 25.4 mm and lengths between 50 mm and 300 mm.

  20. Invited review: Experimental design, data reporting, and sharing in support of animal systems modeling research.

    Science.gov (United States)

    McNamara, J P; Hanigan, M D; White, R R

    2016-12-01

    The National Animal Nutrition Program "National Research Support Project 9" supports efforts in livestock nutrition, including the National Research Council's committees on the nutrient requirements of animals. Our objective was to review the status of experimentation and data reporting in animal nutrition literature and to provide suggestions for the advancement of animal nutrition research and the ongoing improvement of field-applied nutrient requirement models. Improved data reporting consistency and completeness represent a substantial opportunity to improve nutrition-related mathematical models. We reviewed a body of nutrition research; recorded common phrases used to describe diets, animals, housing, and environmental conditions; and proposed equivalent numerical data that could be reported. With the increasing availability of online supplementary material sections in journals, we developed a comprehensive checklist of data that should be included in publications. To continue to improve our research effectiveness, studies utilizing multiple research methodologies to address complex systems and measure multiple variables will be necessary. From the current body of animal nutrition literature, we identified a series of opportunities to integrate research focuses (nutrition, reproduction and genetics) to advance the development of nutrient requirement models. From our survey of current experimentation and data reporting in animal nutrition, we identified 4 key opportunities to advance animal nutrition knowledge: (1) coordinated experiments should be designed to employ multiple research methodologies; (2) systems-oriented research approaches should be encouraged and supported; (3) publication guidelines should be updated to encourage and support sharing of more complete data sets; and (4) new experiments should be more rapidly integrated into our knowledge bases, research programs and practical applications. Copyright © 2016 American Dairy Science Association

  1. The current duration design for estimating the time to pregnancy distribution

    DEFF Research Database (Denmark)

    Gasbarra, Dario; Arjas, Elja; Vehtari, Aki

    2015-01-01

    This paper was inspired by the studies of Niels Keiding and co-authors on estimating the waiting time-to-pregnancy (TTP) distribution, and in particular on using the current duration design in that context. In this design, a cross-sectional sample of women is collected from those who are currently...... attempting to become pregnant, and then by recording from each the time she has been attempting. Our aim here is to study the identifiability and the estimation of the waiting time distribution on the basis of current duration data. The main difficulty in this stems from the fact that very short waiting...

  2. Scaffolded Instruction Improves Student Understanding of the Scientific Method & Experimental Design

    Science.gov (United States)

    D'Costa, Allison R.; Schlueter, Mark A.

    2013-01-01

    Implementation of a guided-inquiry lab in introductory biology classes, along with scaffolded instruction, improved students' understanding of the scientific method, their ability to design an experiment, and their identification of experimental variables. Pre- and postassessments from experimental versus control sections over three semesters…

  3. Experimental Device for Learning of Logical Circuit Design using Integrated Circuits

    OpenAIRE

    石橋, 孝昭

    2012-01-01

    This paper presents an experimental device for learning of logical circuit design using integrated circuits and breadboards. The experimental device can be made at a low cost and can be used for many subjects such as logical circuits, computer engineering, basic electricity, electrical circuits and electronic circuits. The proposed device is effective to learn the logical circuits than the usual lecture.

  4. A Contribution to the phono-kinetic approach: An architectural experimentation to design a public shelter

    Directory of Open Access Journals (Sweden)

    Gregoire Chelkoff

    2011-12-01

    Full Text Available Despite the current evolution of several tools that help understanding, representing and constructing a better awareness of sound and more generally the sensory qualities of the built environment, the integration of sonic dimension in the ordinary architectural production remains difficult. Sonic dimension is still undervalued considered as an accessory or as a second dimension of the space. Till now, the sonic quality doesn’t have its legitimacy in the architectural and urban thinking except in specific situations where designer should solve certain problems of noise and propagation. Therefore, we should find the appropriate qualitative criteria of the architectural elements that don’t only integrate the perceptive aspects but also the action. In this sense, we shall present an experimentation that has been elaborated to clarify the relationship between sound and movement or sound and action in order to design spatial architectural elements. How can we identify the sonic role during the spatial experiment and explore the different corporal and movement modalities that emerge by hearing? We postulate that the actions potentials that emerge in a sonic context must be considered as an alternative that can modulate the environment in space and time[1]. [1] This paper is based on another article : Approche écologique de kinesthèses sonores : expérimentation d'un prototype d'abri public et ergonomie acoustique, Acoustique et techniques, n° 41, 2005, pp. 24-31

  5. Design of a high-temperature superconductor current lead for electric utility SMES

    Science.gov (United States)

    Niemann, R. C.; Cha, Y. S.; Hull, J. R.; Rey, C. M.; Dixon, K. D.

    Current leads that rely on high-temperature superconductors (HTS's) to deliver power to devices operating at liquid helium temperature have the potential to reduce refrigeration requirements to levels significantly below those achievable with conventional leads. The design of HTS current leads suitable for use in near-term superconducting magnetic energy storage (SMES) is in progress. The SMES system has an 0.5 MWh energy capacity and a discharge power of 30 MW. Lead-design considerations include safety and reliability, electrical and thermal performance, structural integrity, manufacturability, and cost. Available details of the design, including materials, configuration, and performance predictions, are presented.

  6. Measuring and Advancing Experimental Design Ability in an Introductory Course without Altering Existing Lab Curriculum†

    Science.gov (United States)

    Shanks, Ryan A.; Robertson, Chuck L.; Haygood, Christian S.; Herdliksa, Anna M.; Herdliska, Heather R.; Lloyd, Steven A.

    2017-01-01

    Introductory biology courses provide an important opportunity to prepare students for future courses, yet existing cookbook labs, although important in their own way, fail to provide many of the advantages of semester-long research experiences. Engaging, authentic research experiences aid biology students in meeting many learning goals. Therefore, overlaying a research experience onto the existing lab structure allows faculty to overcome barriers involving curricular change. Here we propose a working model for this overlay design in an introductory biology course and detail a means to conduct this lab with minimal increases in student and faculty workloads. Furthermore, we conducted exploratory factor analysis of the Experimental Design Ability Test (EDAT) and uncovered two latent factors which provide valid means to assess this overlay model’s ability to increase advanced experimental design abilities. In a pre-test/post-test design, we demonstrate significant increases in both basic and advanced experimental design abilities in an experimental and comparison group. We measured significantly higher gains in advanced experimental design understanding in students in the experimental group. We believe this overlay model and EDAT factor analysis contribute a novel means to conduct and assess the effectiveness of authentic research experiences in an introductory course without major changes to the course curriculum and with minimal increases in faculty and student workloads. PMID:28904647

  7. Measuring and Advancing Experimental Design Ability in an Introductory Course without Altering Existing Lab Curriculum

    Directory of Open Access Journals (Sweden)

    Ryan A. Shanks

    2017-05-01

    Full Text Available Introductory biology courses provide an important opportunity to prepare students for future courses, yet existing cookbook labs, although important in their own way, fail to provide many of the advantages of semester-long research experiences. Engaging, authentic research experiences aid biology students in meeting many learning goals. Therefore, overlaying a research experience onto the existing lab structure allows faculty to overcome barriers involving curricular change. Here we propose a working model for this overlay design in an introductory biology course and detail a means to conduct this lab with minimal increases in student and faculty workloads. Furthermore, we conducted exploratory factor analysis of the Experimental Design Ability Test (EDAT and uncovered two latent factors which provide valid means to assess this overlay model’s ability to increase advanced experimental design abilities. In a pre-test/post-test design, we demonstrate significant increases in both basic and advanced experimental design abilities in an experimental and comparison group. We measured significantly higher gains in advanced experimental design understanding in students in the experimental group. We believe this overlay model and EDAT factor analysis contribute a novel means to conduct and assess the effectiveness of authentic research experiences in an introductory course without major changes to the course curriculum and with minimal increases in faculty and student workloads.

  8. 'I think it will eventually be done away with': Attitudes among healthcare professionals towards the current system of animal experimentation.

    Science.gov (United States)

    Dignon, Andrée

    2016-08-01

    This article describes a study of attitudes to the current system of animal experimentation (for the production of health interventions) among 52 UK healthcare professionals. These healthcare professionals participated in three separate focus groups (of 18, 17 and 17 participants) and were invited to respond to the question 'what is your opinion about the current system of animal testing?' The study focused specifically on their views of the current system (rather than their views of animal testing in general). The healthcare professionals were critical of the current system, particularly with regard to regulation, secrecy, validity, unnecessary suffering and welfare. © The Author(s) 2014.

  9. Analysis of Advanced Fuel Assemblies and Core Designs for the Current and Next Generations of LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Ragusa, Jean; Vierow, Karen

    2011-09-01

    The objective of the project is to design and analyze advanced fuel assemblies for use in current and future light water reactors and to assess their ability to reduce the inventory of transuranic elements, while preserving operational safety. The reprocessing of spent nuclear fuel can delay or avoid the need for a second geological repository in the US. Current light water reactor fuel assembly designs under investigation could reduce the plutonium inventory of reprocessed fuel. Nevertheless, these designs are not effective in stabilizing or reducing the inventory of minor actinides. In the course of this project, we developed and analyzed advanced fuel assembly designs with improved thermal transmutation capability regarding transuranic elements and especially minor actinides. These designs will be intended for use in thermal spectrum (e.g., current and future fleet of light water reactors in the US). We investigated various fuel types, namely high burn-up advanced mixed oxides and inert matrix fuels, in various geometrical designs that are compliant with the core internals of current and future light water reactors. Neutronic/thermal hydraulic effects were included. Transmutation efficiency and safety parameters were used to rank and down-select the various designs.

  10. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    OpenAIRE

    Marcel Crul; Long Nguyen Hong; Garrette Clark; Justin Kosoris

    2009-01-01

    The Design for Sustainability (D4S) concept outlines methodologies for making sustainable improvements (social, economic and environmental) to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includes both incremental and radical innovation. The United Nations Environment Programme and the Delft University of Technology, the Netherlands, in concert with key partners, work to support, illustra...

  11. An assessment of recently published gene expression data analyses: reporting experimental design and statistical factors

    Directory of Open Access Journals (Sweden)

    Azuaje Francisco

    2006-06-01

    Full Text Available Abstract Background The analysis of large-scale gene expression data is a fundamental approach to functional genomics and the identification of potential drug targets. Results derived from such studies cannot be trusted unless they are adequately designed and reported. The purpose of this study is to assess current practices on the reporting of experimental design and statistical analyses in gene expression-based studies. Methods We reviewed hundreds of MEDLINE-indexed papers involving gene expression data analysis, which were published between 2003 and 2005. These papers were examined on the basis of their reporting of several factors, such as sample size, statistical power and software availability. Results Among the examined papers, we concentrated on 293 papers consisting of applications and new methodologies. These papers did not report approaches to sample size and statistical power estimation. Explicit statements on data transformation and descriptions of the normalisation techniques applied prior to data analyses (e.g. classification were not reported in 57 (37.5% and 104 (68.4% of the methodology papers respectively. With regard to papers presenting biomedical-relevant applications, 41(29.1 % of these papers did not report on data normalisation and 83 (58.9% did not describe the normalisation technique applied. Clustering-based analysis, the t-test and ANOVA represent the most widely applied techniques in microarray data analysis. But remarkably, only 5 (3.5% of the application papers included statements or references to assumption about variance homogeneity for the application of the t-test and ANOVA. There is still a need to promote the reporting of software packages applied or their availability. Conclusion Recently-published gene expression data analysis studies may lack key information required for properly assessing their design quality and potential impact. There is a need for more rigorous reporting of important experimental

  12. Optimum Experimental Design applied to MEMS accelerometer calibration for 9-parameter auto-calibration model.

    Science.gov (United States)

    Ye, Lin; Su, Steven W

    2015-01-01

    Optimum Experimental Design (OED) is an information gathering technique used to estimate parameters, which aims to minimize the variance of parameter estimation and prediction. In this paper, we further investigate an OED for MEMS accelerometer calibration of the 9-parameter auto-calibration model. Based on a linearized 9-parameter accelerometer model, we show the proposed OED is both G-optimal and rotatable, which are the desired properties for the calibration of wearable sensors for which only simple calibration devices are available. The experimental design is carried out with a newly developed wearable health monitoring device and desired experimental results have been achieved.

  13. Two current experimental problems in heavy lepton physics: tau decay modes and close mass pairs

    Energy Technology Data Exchange (ETDEWEB)

    Perl, M.L.

    1987-08-01

    This paper investigates tau lepton decay modes and close-mass lepton pairs. The major part of the paper discusses branching functions from experimental and theoretical viewpoints. Finally, the lack of experimental signatures of close-mass lepton pairs are reviewed. 15 refs., 2 figs., 11 tabs. (JDH)

  14. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    Directory of Open Access Journals (Sweden)

    Marcel Crul

    2009-08-01

    Full Text Available The Design for Sustainability (D4S concept outlines methodologies for making sustainable improvements (social, economic and environmental to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includes both incremental and radical innovation. The United Nations Environment Programme and the Delft University of Technology, the Netherlands, in concert with key partners, work to support, illustrate, and diffuse targeted D4S demonstration efforts, including the European Commission-funded Cleaner Production for Better Products project in Vietnam, that are needed to change unsustainable consumption and production patterns.

  15. Experimental validation of systematically designed acoustic hyperbolic meta material slab exhibiting negative refraction

    DEFF Research Database (Denmark)

    Christiansen, Rasmus Ellebæk; Sigmund, Ole

    2016-01-01

    This Letter reports on the experimental validation of a two-dimensional acoustic hyperbolic metamaterial slab optimized to exhibit negative refractive behavior. The slab was designed using a topology optimization based systematic design method allowing for tailoring the refractive behavior. The e...

  16. A Sino-Finnish Initiative for Experimental Teaching Practices Using the Design Factory Pedagogical Platform

    Science.gov (United States)

    Björklund, Tua A.; Nordström, Katrina M.; Clavert, Maria

    2013-01-01

    The paper presents a Sino-Finnish teaching initiative, including the design and experiences of a series of pedagogical workshops implemented at the Aalto-Tongji Design Factory (DF), Shanghai, China, and the experimentation plans collected from the 54 attending professors and teachers. The workshops aimed to encourage trying out interdisciplinary…

  17. Mobilities Design – towards an experimental field of research and practice

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Lanng, Ditte Bendix

    2016-01-01

    and physical form. The exchange value with design is twofold; first this means getting closer to the ‘material’ which is needed if mobilities research can claim to have understood contemporary mobilities, second it means that the creative, explorative and experimental approaches of the design world becomes...

  18. Overview of design development of FCC-hh Experimental Interaction Regions

    CERN Document Server

    Seryi, Andrei; Cruz Alaniz, Emilia; Van Riesen-Haupt, Leon; Benedikt, Michael; Besana, Maria Ilaria; Buffat, Xavier; Burkhardt, Helmut; Cerutti, Francesco; Langner, Andy Sven; Martin, Roman; Riegler, Werner; Schulte, Daniel; Tomas Garcia, Rogelio; Appleby, Robert Barrie; Rafique, Haroon; Barranco Garcia, Javier; Pieloni, Tatiana; Boscolo, Manuela; Collamati, Francesco; Nevay, Laurence James; Hofer, Michael

    2017-01-01

    The experimental interaction region (EIR) is one of the key areas that define the performance of the Future Circular Collider. In this overview we will describe the status and the evolution of the design of EIR of FCC-hh, focusing on design of the optics, energy deposition in EIR elements, beam-beam effects and machine detector interface issues.

  19. A Sino-Finnish Initiative for Experimental Teaching Practices Using the Design Factory Pedagogical Platform

    Science.gov (United States)

    Björklund, Tua A.; Nordström, Katrina M.; Clavert, Maria

    2013-01-01

    The paper presents a Sino-Finnish teaching initiative, including the design and experiences of a series of pedagogical workshops implemented at the Aalto-Tongji Design Factory (DF), Shanghai, China, and the experimentation plans collected from the 54 attending professors and teachers. The workshops aimed to encourage trying out interdisciplinary…

  20. Experimental and Theoretical Progress of Linear Collider Final Focus Design and ATF2 Facility

    CERN Document Server

    Seryi, Andrei; Zimmermann, Frank; Kubo, Kiyoshi; Kuroda, Shigeru; Okugi, Toshiyuki; Tauchi, Toshiaki; Terunuma, Nobuhiro; Urakawa, Junji; White, Glen; Woodley, Mark; Angal-Kalinin, Deepa

    2014-01-01

    In this brief overview we will reflect on the process of the design of the linear collider (LC) final focus (FF) optics, and will also describe the theoretical and experimental efforts on design and practical realisation of a prototype of the LC FF optics implemented in the ATF2 facility at KEK, Japan, presently being commissioned and operated.

  1. Assessing the Effectiveness of a Computer Simulation for Teaching Ecological Experimental Design

    Science.gov (United States)

    Stafford, Richard; Goodenough, Anne E.; Davies, Mark S.

    2010-01-01

    Designing manipulative ecological experiments is a complex and time-consuming process that is problematic to teach in traditional undergraduate classes. This study investigates the effectiveness of using a computer simulation--the Virtual Rocky Shore (VRS)--to facilitate rapid, student-centred learning of experimental design. We gave a series of…

  2. Scaffolding a Complex Task of Experimental Design in Chemistry with a Computer Environment

    Science.gov (United States)

    Girault, Isabelle; d'Ham, Cédric

    2014-01-01

    When solving a scientific problem through experimentation, students may have the responsibility to design the experiment. When students work in a conventional condition, with paper and pencil, the designed procedures stay at a very general level. There is a need for additional scaffolds to help the students perform this complex task. We propose a…

  3. Development and Validation of a Rubric for Diagnosing Students' Experimental Design Knowledge and Difficulties

    Science.gov (United States)

    Dasgupta, Annwesa P.; Anderson, Trevor R.; Pelaez, Nancy

    2014-01-01

    It is essential to teach students about experimental design, as this facilitates their deeper understanding of how most biological knowledge was generated and gives them tools to perform their own investigations. Despite the importance of this area, surprisingly little is known about what students actually learn from designing biological…

  4. Using a Discussion about Scientific Controversy to Teach Central Concepts in Experimental Design

    Science.gov (United States)

    Bennett, Kimberley Ann

    2015-01-01

    Students may need explicit training in informal statistical reasoning in order to design experiments or use formal statistical tests effectively. By using scientific scandals and media misinterpretation, we can explore the need for good experimental design in an informal way. This article describes the use of a paper that reviews the measles mumps…

  5. The application of analysis of variance (ANOVA) to different experimental designs in optometry.

    Science.gov (United States)

    Armstrong, R A; Eperjesi, F; Gilmartin, B

    2002-05-01

    Analysis of variance (ANOVA) is the most efficient method available for the analysis of experimental data. Analysis of variance is a method of considerable complexity and subtlety, with many different variations, each of which applies in a particular experimental context. Hence, it is possible to apply the wrong type of ANOVA to data and, therefore, to draw an erroneous conclusion from an experiment. This article reviews the types of ANOVA most likely to arise in clinical experiments in optometry including the one-way ANOVA ('fixed' and 'random effect' models), two-way ANOVA in randomised blocks, three-way ANOVA, and factorial experimental designs (including the varieties known as 'split-plot' and 'repeated measures'). For each ANOVA, the appropriate experimental design is described, a statistical model is formulated, and the advantages and limitations of each type of design discussed. In addition, the problems of non-conformity to the statistical model and determination of the number of replications are considered.

  6. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design

    Science.gov (United States)

    Rifai, Damhuji; Abdalla, Ahmed N.; Razali, Ramdan; Ali, Kharudin; Faraj, Moneer A.

    2017-01-01

    The use of the eddy current technique (ECT) for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT) use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR) sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM). The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient. PMID:28335399

  7. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design.

    Science.gov (United States)

    Rifai, Damhuji; Abdalla, Ahmed N; Razali, Ramdan; Ali, Kharudin; Faraj, Moneer A

    2017-03-13

    The use of the eddy current technique (ECT) for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT) use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR) sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM). The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient.

  8. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design

    Directory of Open Access Journals (Sweden)

    Damhuji Rifai

    2017-03-01

    Full Text Available The use of the eddy current technique (ECT for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM. The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient.

  9. Behavior of a DC zero-flux current sensor; Magnetic field analysis and comparison with experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Campostrini, P.; Sonato, P. (Istituto Gas Ionizzati del CNR, Padova (IT))

    1991-09-01

    In this paper the magnetic section of the finite-element ANSYS code, and in particular its optimization feature has been used to predict the behaviour of a zero-flux current sensor, briefly described, which is intended to be used in a fusion experiment to measure pulsed currents up to 50 kA, over a bandwidth from DC to 10 k Hz. The computed results fit well with those coming from experimental tests performed on a prototype.

  10. An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays.

    Science.gov (United States)

    Manservisi, Fabiana; Marquillas, Clara Babot; Buscaroli, Annalisa; Huff, James; Lauriola, Michelina; Mandrioli, Daniele; Manservigi, Marco; Panzacchi, Simona; Silbergeld, Ellen K; Belpoggi, Fiorella

    2017-03-01

    For nearly five decades long-term studies in rodents have been the accepted benchmark for assessing chronic long-term toxic effects, particularly carcinogenicity, of chemicals. The European Food Safety Authority (EFSA) and the World Health Organization (WHO) have pointed out that the current set of internationally utilized test methods capture only some of the potential adverse effects associated with exposures to these agents over the lifetime. In this paper, we propose the adaption of the carcinogenicity bioassay to integrate additional protocols for comprehensive long-term toxicity assessment that includes developmental exposures and long-term outcomes, capable of generating information on a broad spectrum of different end points. An integrated study design based on a stepwise process is described that includes the priority end points of the Economic Co-operation and Development and the National Toxicology Program guidelines on carcinogenicity and chronic toxicity and developmental and reproductive toxicity. Integrating a comprehensive set of relevant toxicological end points in a single protocol represents an opportunity to optimize animal use in accordance with the 3Rs (replacement, reduction and refinement). This strategy has the potential to provide sufficient data on multiple windows of susceptibility of specific interest for risk assessments and public health decision-making by including prenatal, lactational, neonatal exposures and evaluating outcomes over the lifespan. This integrated study design is efficient in that the same generational cohort of rats used for evaluating long-term outcomes can be monitored in satellite parallel experiments to measure biomarkers and other parameters related to system-specific responses including metabolic alterations and endocrine disturbances. Citation: Manservisi F, Babot Marquillas C, Buscaroli A, Huff J, Lauriola M, Mandrioli D, Manservigi M, Panzacchi S, Silbergeld EK, Belpoggi F. 2017. An integrated experimental

  11. Multi-objective optimization design and experimental investigation of centrifugal fan performance

    Science.gov (United States)

    Zhang, Lei; Wang, Songling; Hu, Chenxing; Zhang, Qian

    2013-11-01

    Current studies of fan performance optimization mainly focus on two aspects: one is to improve the blade profile, and another is only to consider the influence of single impeller structural parameter on fan performance. However, there are few studies on the comprehensive effect of the key parameters such as blade number, exit stagger angle of blade and the impeller outlet width on the fan performance. The G4-73 backward centrifugal fan widely used in power plants is selected as the research object. Based on orthogonal design and BP neural network, a model for predicting the centrifugal fan performance parameters is established, and the maximum relative errors of the total pressure and efficiency are 0.974% and 0.333%, respectively. Multi-objective optimization of total pressure and efficiency of the fan is conducted with genetic algorithm, and the optimum combination of impeller structural parameters is proposed. The optimized parameters of blade number, exit stagger angle of blade and the impeller outlet width are seperately 14, 43.9°, and 21 cm. The experiments on centrifugal fan performance and noise are conducted before and after the installation of the new impeller. The experimental results show that with the new impeller, the total pressure of fan increases significantly in total range of the flow rate, and the fan efficiency is improved when the relative flow is above 75%, also the high efficiency area is broadened. Additionally, in 65% -100% relative flow, the fan noise is reduced. Under the design operating condition, total pressure and efficiency of the fan are improved by 6.91% and 0.5%, respectively. This research sheds light on the considering of comprehensive effect of impeller structrual parameters on fan performance, and a new impeller can be designed to satisfy the engineering demand such as energy-saving, noise reduction or solving air pressure insufficiency for power plants.

  12. Visualizing Experimental Designs for Balanced ANOVA Models using Lisp-Stat

    Directory of Open Access Journals (Sweden)

    Philip W. Iversen

    2004-12-01

    Full Text Available The structure, or Hasse, diagram described by Taylor and Hilton (1981, American Statistician provides a visual display of the relationships between factors for balanced complete experimental designs. Using the Hasse diagram, rules exist for determining the appropriate linear model, ANOVA table, expected means squares, and F-tests in the case of balanced designs. This procedure has been implemented in Lisp-Stat using a software representation of the experimental design. The user can interact with the Hasse diagram to add, change, or delete factors and see the effect on the proposed analysis. The system has potential uses in teaching and consulting.

  13. Two-Stage Experimental Design for Dose–Response Modeling in Toxicology Studies

    OpenAIRE

    Wang, Kai; Yang, Feng; Porter, Dale W; Wu, Nianqiang

    2013-01-01

    The efficient design of experiments (i.e., selection of experimental doses and allocation of animals) is important to establishing dose–response relationships in toxicology studies. The proposed procedure for design of experiments is distinct from those in the literature because it is able to adequately accommodate the special features of the dose–response data, which include non-normality, variance heterogeneity, possibly nonlinearity of the dose–response curve, and data scarcity. The design...

  14. An Empirical Study of Parameter Estimation for Stated Preference Experimental Design

    Directory of Open Access Journals (Sweden)

    Fei Yang

    2014-01-01

    Full Text Available The stated preference experimental design can affect the reliability of the parameters estimation in discrete choice model. Some scholars have proposed some new experimental designs, such as D-efficient, Bayesian D-efficient. But insufficient empirical research has been conducted on the effectiveness of these new designs and there has been little comparative analysis of the new designs against the traditional designs. In this paper, a new metro connecting Chengdu and its satellite cities is taken as the research subject to demonstrate the validity of the D-efficient and Bayesian D-efficient design. Comparisons between these new designs and orthogonal design were made by the fit of model and standard deviation of parameters estimation; then the best model result is obtained to analyze the travel choice behavior. The results indicate that Bayesian D-efficient design works better than D-efficient design. Some of the variables can affect significantly the choice behavior of people, including the waiting time and arrival time. The D-efficient and Bayesian D-efficient design for MNL can acquire reliability result in ML model, but the ML model cannot develop the theory advantages of these two designs. Finally, the metro can handle over 40% passengers flow if the metro will be operated in the future.

  15. Wind refrigeration : design and results of an experimental facility; Refrigeracion eolica: Diseno y resultados de una instalacion experimental

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, R. G.; Talero, A.

    2004-07-01

    This article describes the experimental setup used to obtain design parameters for a wind driven refrigeration equipment. The system compressor is directly coupled to the wind mill and will provide refrigeration to a community located in La Guajira in northern Colombia. The testing on the experimental installation assessed the refrigeration capacity that could be provided by an open type commercial compressor coupled to the wind mill axis. Power and torque requirements have been evaluated for different wind mill rotational speeds. An assessment of the local conditions relating to wind speed, frequency and preferred direction for the installation site has been made based on measurements by the Meteorological National Institute and independent data from other sources. (Author)

  16. Design automation techniques for high-resolution current folding and interpolating CMOS A/D converters

    Science.gov (United States)

    Gevaert, D.

    2007-05-01

    The design and testing of a 12-bit Analog-to-Digital (A/D) converter, in current mode, arranged in an 8-bit LSB and a 4- bit MSB architecture together with the integration of specialized test building blocks on chip allows the set up of a design automation technique for current folding and interpolation CMOS A/D converter architectures. The presented design methodology focuses on the automation for CMOS A/D building blocks in a flexible target current folding and interpolating architecture for a downscaling technology and for different quality specifications. The comprehensive understanding of all sources of mismatching in the crucial building blocks and the use of physical based mismatch modeling in the prediction of mismatch errors, more adequate and realistic sizing of all transistors will result in an overall area reduction of the A/D converter. In this design the folding degree is 16, the number of folders is 64 and the interpolation level is 4. The number of folders is reduced by creating intermediate folding signals with a 4-level interpolator based on current division techniques. Current comparators detect the zero-crossing between the differential folder output currents. The outputs of the comparators deliver a cyclic thermometer code. The digital synthesis part for decoding and error correction building blocks is a standardized digital standard cell design. The basic building blocks in the target architecture were designed in 0.35μ CMOS technology; they are suitable for topological reuse and are in an automated way downscaled into a 0.18μ CMOS technology.

  17. Novel design for centrifugal counter-current chromatography: VI. Ellipsoid column.

    Science.gov (United States)

    Gu, Dongyu; Yang, Yi; Xin, Xuelei; Aisa, Haji Akber; Ito, Yoichiro

    2015-01-01

    A novel ellipsoid column was designed for centrifugal counter-current chromatography. Performance of the ellipsoid column with a capacity of 3.4 mL was examined with three different solvent systems composed of 1-butanol-acetic acid-water (4:1:5, v/v) (BAW), hexane-ethyl acetate-methanol-0.1 M HCl (1:1:1:1, v/v) (HEMH), and 12.5% (w/w) PEG1000 and 12.5% (w/w) dibasic potassium phosphate in water (PEG-DPP) each with suitable test samples. In dipeptide separation with BAW system, both stationary phase retention (Sf) and peak resolution (Rs) of the ellipsoid column were much higher at 0° column angle (column axis parallel to the centrifugal force) than at 90° column angle (column axis perpendicular to the centrifugal force), where elution with the lower phase at a low flow rate produced the best separation yielding Rs at 2.02 with 27.8% Sf at a flow rate of 0.07 ml/min. In the DNP-amino acid separation with HEMW system, the best results were obtained at a flow rate of 0.05 ml/min with 31.6% Sf yielding high Rs values at 2.16 between DNP-DL-glu and DNP-β-ala peaks and 1.81 between DNP-β-ala and DNP-L-ala peaks. In protein separation with PEG-DPP system, lysozyme and myolobin were resolved at Rs of 1.08 at a flow rate of 0.03 ml/min with 38.9% Sf. Most of those Rs values exceed those obtained from the figure-8 column under similar experimental conditions previously reported.

  18. Faculty perceptions of the strengths, weaknesses and future prospects of the current medical undergraduate experimental physiology curriculum in Gujarat, India.

    Science.gov (United States)

    Paralikar, Swapnil; Shah, Chinmay

    2015-01-01

    Over the past several years, an opinion has emerged in India that the current practical curricula in medical schools fail to meet many of the objectives for which they were instituted. Hence, this study has assessed the perception of physiology faculty members regarding the current experimental physiology curriculum in one Indian state, Gujarat. The faculty were of the opinion that many of the topics currently taught in experimental physiology (amphibian nerve-muscle and heart muscle experiments) were outdated and clinically irrelevant: Therefore, the faculty advocated that duration of teaching time devoted to some of these topics should be reduced and topics with clinical relevance should be introduced at the undergraduate level. The faculty also felt that more emphasis should be laid on highlighting the clinical aspect related to each concept taught in experimental physiology . Moreover, a majority of faculty members were in favour of replacing the current practice in Gujarat of teaching experimental physiology only by explanation of graphs obtained from experiments conducted in the previous years, with computer assisted learning in small groups.

  19. A mechanical connector design for high-current, high-coulomb pulsed power systems

    Energy Technology Data Exchange (ETDEWEB)

    Susoeff, A.R.; Hawke, R.S.; Leighton, K.S.

    1992-02-25

    A technique to make reliable high-current, high-coulomb electrical contact was developed for transmitting power into railguns. The method uses spring loaded removable connectors that are installed independently from the launcher. The simple rod-type design and absence of fastener holes allow maximum utilization of material mechanical properties. Repeated experiments with 9.5-mm diameter connectors demonstrated reliable pulsed charge transfer of 200 coulombs at currents of over 400kA. 20 refs.

  20. Design study of a beta=0.09 high current superconducting half wave resonator

    CERN Document Server

    Zhong, Hu-Tan-Xiang; Fan, Pei-Liang; Quan, Sheng-Wen; Liu, Ke-Xin

    2016-01-01

    There's presently a growing demand for high current proton and deuteron linear accelerators based on superconducting technology to better support various fields of science. A \\b{eta}=0.09 162.5 MHz high current superconducting half wave resonator (HWR) has been designed at Peking University to accelerate 100 mA proton beam or 50 mA deuteron beam after the RFQ accelerating structure. The detailed electromagnetic design, multipacting simulation, mechanical analysis of the cavity will be given in this paper.

  1. Theoretical and Experimental Study of the Primary Current Distribution in Parallel-Plate Electrochemical Reactors

    Science.gov (United States)

    Vazquez Aranda, Armando I.; Henquin, Eduardo R.; Torres, Israel Rodriguez; Bisang, Jose M.

    2012-01-01

    A laboratory experiment is described to determine the primary current distribution in parallel-plate electrochemical reactors. The electrolyte is simulated by conductive paper and the electrodes are segmented to measure the current distribution. Experiments are reported with the electrolyte confined to the interelectrode gap, where the current…

  2. Determination of hydroxy acids in cosmetics by chemometric experimental design and cyclodextrin-modified capillary electrophoresis.

    Science.gov (United States)

    Liu, Pei-Yu; Lin, Yi-Hui; Feng, Chia Hsien; Chen, Yen-Ling

    2012-10-01

    A CD-modified CE method was established for quantitative determination of seven hydroxy acids in cosmetic products. This method involved chemometric experimental design aspects, including fractional factorial design and central composite design. Chemometric experimental design was used to enhance the method's separation capability and to explore the interactions between parameters. Compared to the traditional investigation that uses multiple parameters, the method that used chemometric experimental design was less time-consuming and lower in cost. In this study, the influences of three experimental variables (phosphate concentration, surfactant concentration, and methanol percentage) on the experimental response were investigated by applying a chromatographic resolution statistic function. The optimized conditions were as follows: a running buffer of 150 mM phosphate solution (pH 7) containing 0.5 mM CTAB, 3 mM γ-CD, and 25% methanol; 20 s sample injection at 0.5 psi; a separation voltage of -15 kV; temperature was set at 25°C; and UV detection at 200 nm. The seven hydroxy acids were well separated in less than 10 min. The LOD (S/N = 3) was 625 nM for both salicylic acid and mandelic acid. The correlation coefficient of the regression curve was greater than 0.998. The RSD and relative error values were all less than 9.21%. After optimization and validation, this simple and rapid analysis method was considered to be established and was successfully applied to several commercial cosmetic products.

  3. Adaptive combinatorial design to explore large experimental spaces: approach and validation.

    Science.gov (United States)

    Lejay, L V; Shasha, D E; Palenchar, P M; Kouranov, A Y; Cruikshank, A A; Chou, M F; Coruzzi, G M

    2004-12-01

    Systems biology requires mathematical tools not only to analyse large genomic datasets, but also to explore large experimental spaces in a systematic yet economical way. We demonstrate that two-factor combinatorial design (CD), shown to be useful in software testing, can be used to design a small set of experiments that would allow biologists to explore larger experimental spaces. Further, the results of an initial set of experiments can be used to seed further 'Adaptive' CD experimental designs. As a proof of principle, we demonstrate the usefulness of this Adaptive CD approach by analysing data from the effects of six binary inputs on the regulation of genes in the N-assimilation pathway of Arabidopsis. This CD approach identified the more important regulatory signals previously discovered by traditional experiments using far fewer experiments, and also identified examples of input interactions previously unknown. Tests using simulated data show that Adaptive CD suffers from fewer false positives than traditional experimental designs in determining decisive inputs, and succeeds far more often than traditional or random experimental designs in determining when genes are regulated by input interactions. We conclude that Adaptive CD offers an economical framework for discovering dominant inputs and interactions that affect different aspects of genomic outputs and organismal responses.

  4. Experimental Phenomena of Improved Ohmic Confinement Induced by Modulated Toroidal Current on the HT-7 Tokamak

    Institute of Scientific and Technical Information of China (English)

    毛剑珊; 罗家融; P.Phillips; 赵君煜; 揭银先; 吴振伟; 胡立群; 李建刚

    2002-01-01

    The phenomena of improved ohmic confinement have been observed during the modulation of the toroidal curranton the Hefei superconducting Tokamak-7 (HT-7). In the experiment, the programming ohmic heating field wasmodulated. A toroidal frequency-modulated current induced by modulated loop voltage was added on the plasmaequilibrium current. The ratio of ac amplitude of the plasma current to the main plasma current is about 12-30%.These improved plasma confinement phenomena include the facts that the average electron density and the centralelectron temperature both increase, the Dα radiation from the edge is reduced, the magnetohydrodynamics isobviously suppressed by oscillating plasma current, eand the global energy confinement time increases by 27-45%o.It is found that the faster the modulation is, the more effective the improved ohmic confinement phase.

  5. Experimental study on directional solidification of Al-Si alloys under the influence of electric currents

    Science.gov (United States)

    Räbiger, D.; Zhang, Y.; Galindo, V.; Franke, S.; Willers, B.; Eckert, S.

    2016-07-01

    The application of electric currents during solidification can cause grain refinement in metallic alloys. However, the knowledge about the mechanisms underlying the decrease in grain size remains fragmentary. This study considers the solidification of Al-Si alloys under the influence of electric currents for the configuration of two parallel electrodes at the free surface. Solidification experiments were performed under the influence of both direct currents (DC) and rectangular electric current pulses (ECP). The interaction between the applied current and its own induced magnetic field causes a Lorentz force which produces an electro-vortex flow. Numerical simulations were conducted to calculate the Lorentz force, the Joule heating and the induced melt flow. The numerical predictions were confirmed by isothermal flow measurements in eutectic GaInSn. The results demonstrate that the grain refining effect observed in our experiments can be ascribed solely to the forced melt flow driven by the Lorentz force.

  6. RHIC 12x150A current lead temperature controller: design and implementation

    Energy Technology Data Exchange (ETDEWEB)

    Mi, C.; Seberg, S.; Ganetis, Hamdi, K.; Louie, W.; Heppner, G.; Jamilkowski, J.; Bruno, D.; DiLieto, A.; Sirio, C.; Tuozzolo, J.; Sandberg, J.; Unger, K.

    2011-03-28

    There are 60 12 x 150A current leads distributed in six RHIC service buildings; each lead delivers power supply current from room temperature to cryogenic temperature in RHIC. Due to the humid environment, condensation occurs frequently and ice forms quickly during operation, especially during an extensive storage period. These conditions generate warnings and alarms to which personnel must respond and establish temporary solutions to keep the machine operating. In here, we designed a temperature control system to avoid such situations. This paper discusses its design, implementation, and some results. There are six service buildings in the RHIC complex; each building has two valve boxes that transfer room-temperature current cables from the power supplies into superconducting leads, and then transport them into the RHIC tunnel. In there, the transition between the room-temperature lead into superconducting lead is critical and essential; smooth running during the physics store is crucial for the machine's continuing operation. One of the problems that often occurred previously was the icing of these current leads that could result in a potential leakage current onto ground, thereby preventing a continuous supply of physics store. Fig. 1 illustrates a typical example on a power lead. Among the modifications of the design of the valve box, we list below the new requirements for designing the temperature controller to prevent icing occurring: (1) Remotely control, monitor, and record each current lead's temperature in real time. Prevent icing or overheating of a power lead. (2) Include a temperature alarm for the high/low level threshold. In this paper we discuss the design, implementation, upgrades to, and operation of this new system.

  7. Experimental Studies of the Heat Transfer to RBCC Rocket Nozzles for CFD Application to Design Methodologies

    Science.gov (United States)

    Santoro, Robert J.; Pal, Sibtosh

    1999-01-01

    Rocket thrusters for Rocket Based Combined Cycle (RBCC) engines typically operate with hydrogen/oxygen propellants in a very compact space. Packaging considerations lead to designs with either axisymmetric or two-dimensional throat sections. Nozzles tend to be either two- or three-dimensional. Heat transfer characteristics, particularly in the throat, where the peak heat flux occurs, are not well understood. Heat transfer predictions for these small thrusters have been made with one-dimensional analysis such as the Bartz equation or scaling of test data from much larger thrusters. The current work addresses this issue with an experimental program that examines the heat transfer characteristics of a gaseous oxygen (GO2)/gaseous hydrogen (GH2) two-dimensional compact rocket thruster. The experiments involved measuring the axial wall temperature profile in the nozzle region of a water-cooled gaseous oxygen/gaseous hydrogen rocket thruster at a pressure of 3.45 MPa. The wall temperature measurements in the thruster nozzle in concert with Bartz's correlation are utilized in a one-dimensional model to obtain axial profiles of nozzle wall heat flux.

  8. Toward best practice in Human Machine Interface design for older drivers: A review of current design guidelines.

    Science.gov (United States)

    Young, K L; Koppel, S; Charlton, J L

    2017-09-01

    Older adults are the fastest growing segment of the driving population. While there is a strong emphasis for older people to maintain their mobility, the safety of older drivers is a serious community concern. Frailty and declines in a range of age-related sensory, cognitive, and physical impairments can place older drivers at an increased risk of crash-related injuries and death. A number of studies have indicated that in-vehicle technologies such as Advanced Driver Assistance Systems (ADAS) and In-Vehicle Information Systems (IVIS) may provide assistance to older drivers. However, these technologies will only benefit older drivers if their design is congruent with the complex needs and diverse abilities of this driving cohort. The design of ADAS and IVIS is largely informed by automotive Human Machine Interface (HMI) guidelines. However, it is unclear to what extent the declining sensory, cognitive and physical capabilities of older drivers are addressed in the current guidelines. This paper provides a review of key current design guidelines for IVIS and ADAS with respect to the extent they address age-related changes in functional capacities. The review revealed that most of the HMI guidelines do not address design issues related to older driver impairments. In fact, in many guidelines driver age and sensory cognitive and physical impairments are not mentioned at all and where reference is made, it is typically very broad. Prescriptive advice on how to actually design a system so that it addresses the needs and limitations of older drivers is not provided. In order for older drivers to reap the full benefits that in-vehicle technology can afford, it is critical that further work establish how older driver limitations and capabilities can be supported by the system design process, including their inclusion into HMI design guidelines. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Experimental Modelling of the Breakdown Voltage of Air Using Design of Experiments

    Directory of Open Access Journals (Sweden)

    REZOUGA, M.

    2009-02-01

    Full Text Available Many experimental and numerical studies were devoted to the electric discharge of air, and some mathematical models were proposed for the critical breakdown voltage. As this latter depends on several parameters, it is difficult to find a formula, theoretical or experimental, which considers many factors. The aim of this paper is to model the critical breakdown voltage in a "Sphere-Sphere� electrodes system by using the methodology of experimental designs. Several factors were considered, such as geometrical factors (inter-electrodes interval, diameter of the electrodes and climatic factors (temperature, humidity. Two factorial centred faces experimental designs (CCF were carried out, a first one for the geometrical factors and a second one for the climatic factors. The obtained results made it possible to propose mathematical models and to study the interactions between the various factors.

  10. Assessment of Current State of Mooring Design in the Danish Wave Energy Sector

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Ferri, Francesco; Kofoed, Jens Peter

    2015-01-01

    The mooring system is a vital part of any floating wave energy converter, both in terms of ensuring station keeping but also as it constitutes a significant share of the total cost. Motivatedby the considerable amount of failures due to insufficient mooring and the cost of mooring today......, the present study outlines the design procedure recommended by design standards and provides considerations on choice of tools for analysis. This is compared to the procedure used by four wave energy converter developers, to illustrate the state of their current mooring design. The study shows a clear...

  11. Experimental design for stable genetic manipulation in mammalian cell lines: lentivirus and alternatives.

    Science.gov (United States)

    Shearer, Robert F; Saunders, Darren N

    2015-01-01

    The use of third-generation lentiviral vectors is now commonplace in most areas of basic biology. These systems provide a fast, efficient means for modulating gene expression, but experimental design needs to be carefully considered to minimize potential artefacts arising from off-target effects and other confounding factors. This review offers a starting point for those new to lentiviral-based vector systems, addressing the main issues involved with the use of lentiviral systems in vitro and outlines considerations which should be taken into account during experimental design. Factors such as selecting an appropriate system and controls, and practical titration of viral transduction are important considerations for experimental design. We also briefly describe some of the more recent advances in genome editing technology. TALENs and CRISPRs offer an alternative to lentivirus, providing endogenous gene editing with reduced off-target effects often at the expense of efficiency.

  12. Experimental evaluation of IGBT junction temperature measurement via peak gate current

    DEFF Research Database (Denmark)

    Baker, Nick; Munk-Nielsen, Stig; Iannuzzo, Francesco

    2015-01-01

    Temperature sensitive electrical parameters allow junction temperature measurements on power semiconductors without modification to module packaging. The peak gate current has recently been proposed for IGBT junction temperature measurement and relies on the temperature dependent resistance of th...

  13. Currents, HF Radio-derived, Monterey Bay, 25 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 25 hour running average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...

  14. Currents, HF Radio-derived, Ano Nuevo, Normal Model, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements, with missing values filled in by a normal...

  15. Currents, HF Radio-derived, SF Bay Outlet, 25 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 25 hour running average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...

  16. Currents, HF Radio-derived, SF Bay, 33 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 33 hour running average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...

  17. Currents, HF Radio-derived, Bodega Bay, 25 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 25 hour running average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...

  18. Currents, HF Radio-derived, Ano Nuevo, 25 hr, Meridional, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 25 hour running average of the meridional component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...

  19. Currents, HF Radio-derived, Ano Nuevo, Normal Model, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements, with missing values filled in by a normal model....

  20. Currents, HF Radio-derived, Ano Nuevo, 25 hr, Zonal, EXPERIMENTAL

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data is the 25 hour running average of the zonal component of ocean surface currents derived from High Frequency Radio-derived measurements. THIS IS AN...