WorldWideScience

Sample records for current design methodologies

  1. Design and Measurement Methodology for a Sub-picoampere Current Digitiser

    CERN Document Server

    Voulgari, Evgenia; Anghinolfi, Francis; Krummenacher, François; Kayal, Maher

    2015-01-01

    This paper introduces some design and measurement techniques that were used in the design and the testing of an ASIC for ultra-low current sensing. The idea behind this paper is to present the limitations in sub-picoampere current measurements and demonstrate an ASIC that can accurately measure the different sources of leakage currents and the methodology of measuring. Then the leakage current can be subtracted or compensated in order to accurately measure the ultra-low current that is generated from a sensor/detector. The proposed ASIC can measure currents as low as -50 fA, a value well below similar ASIC implementations.

  2. Design Methodology - Design Synthesis

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup

    2003-01-01

    ABSTRACT Design Methodology shall be seen as our understanding of how to design; it is an early (emerging late 60ies) and original articulation of teachable and learnable methodics. The insight is based upon two sources: the nature of the designed artefacts and the nature of human designing. Today...... Design Methodology is part of our practice and our knowledge about designing, and it has been strongly supported by the establishing and work of a design research community. The aim of this article is to broaden the reader¿s view of designing and Design Methodology. This is done by sketching...... the development of Design Methodology through time and sketching some important approaches and methods. The development is mainly forced by changing industrial condition, by the growth of IT support for designing, but also by the growth of insight into designing created by design researchers....

  3. Pipeline ADC Design Methodology

    OpenAIRE

    Zhao, Hui

    2012-01-01

    Demand for high-performance analog-to-digital converter (ADC) integrated circuits (ICs) with optimal combined specifications of resolution, sampling rate and power consumption becomes dominant due to emerging applications in wireless communications, broad band transceivers, digital-intermediate frequency (IF) receivers and countless of digital devices. This research is dedicated to develop a pipeline ADC design methodology with minimum power dissipation, while keeping relatively high speed an...

  4. Pipeline ADC Design Methodology

    OpenAIRE

    Zhao, Hui

    2012-01-01

    Demand for high-performance analog-to-digital converter (ADC) integrated circuits (ICs) with optimal combined specifications of resolution, sampling rate and power consumption becomes dominant due to emerging applications in wireless communications, broad band transceivers, digital-intermediate frequency (IF) receivers and countless of digital devices. This research is dedicated to develop a pipeline ADC design methodology with minimum power dissipation, while keeping relatively high speed an...

  5. Systems engineering agile design methodologies

    CERN Document Server

    Crowder, James A

    2013-01-01

    This book examines the paradigm of the engineering design process. The authors discuss agile systems and engineering design. The book captures the entire design process (functionbases), context, and requirements to affect real reuse. It provides a methodology for an engineering design process foundation for modern and future systems design. This book captures design patterns with context for actual Systems Engineering Design Reuse and contains a new paradigm in Design Knowledge Management.

  6. Reflections on Design Methodology Research

    DEFF Research Database (Denmark)

    2011-01-01

    We shall reflect on the results of Design Methodology research and their impact on design practice. In the past 50 years the number of researchers in the field has expanded enormously – as has the number of publications. During the same period design practice and its products have changed...... and produced are also now far more complex and distributed, putting designers under ever increasing pressure. We shall address the question: Are the results of Design Methodology research appropriate and are they delivering the expected results in design practice? In our attempt to answer this question we...... shall draw on our extensive experience of design research and design teaching, and on the recent book The Future of Design Methodology, edited by Professor Herbert Birkhofer. We shall also refer to a model that links the Results, Practices, Methods, and Sciences of designing. Some initial conclusions...

  7. Permanent magnet design methodology

    Science.gov (United States)

    Leupold, Herbert A.

    1991-01-01

    Design techniques developed for the exploitation of high energy magnetically rigid materials such as Sm-Co and Nd-Fe-B have resulted in a revolution in kind rather than in degree in the design of a variety of electron guidance structures for ballistic and aerospace applications. Salient examples are listed. Several prototype models were developed. These structures are discussed in some detail: permanent magnet solenoids, transverse field sources, periodic structures, and very high field structures.

  8. Electric drive design methodology

    CERN Document Server

    Jufer, Marcel

    2013-01-01

    An electric drive that is designed or adapted to a specific application must take into account all the elements of the chain of constituent elements in its use and deployment. In addition to the motor, the transmission, power electronics, control, sensors, and electrical protection systems must be taken into account. The motor and the transmission can be optimized and designed to obtain the best energy efficiency assessment, in particular for dynamic nodes. An inventory and a characterization of these various components is proposed as part of this book's examination and explanation

  9. Current trends in Bayesian methodology with applications

    CERN Document Server

    Upadhyay, Satyanshu K; Dey, Dipak K; Loganathan, Appaia

    2015-01-01

    Collecting Bayesian material scattered throughout the literature, Current Trends in Bayesian Methodology with Applications examines the latest methodological and applied aspects of Bayesian statistics. The book covers biostatistics, econometrics, reliability and risk analysis, spatial statistics, image analysis, shape analysis, Bayesian computation, clustering, uncertainty assessment, high-energy astrophysics, neural networking, fuzzy information, objective Bayesian methodologies, empirical Bayes methods, small area estimation, and many more topics.Each chapter is self-contained and focuses on

  10. Unattended Monitoring System Design Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Drayer, D.D.; DeLand, S.M.; Harmon, C.D.; Matter, J.C.; Martinez, R.L.; Smith, J.D.

    1999-07-08

    A methodology for designing Unattended Monitoring Systems starting at a systems level has been developed at Sandia National Laboratories. This proven methodology provides a template that describes the process for selecting and applying appropriate technologies to meet unattended system requirements, as well as providing a framework for development of both training courses and workshops associated with unattended monitoring. The design and implementation of unattended monitoring systems is generally intended to respond to some form of policy based requirements resulting from international agreements or domestic regulations. Once the monitoring requirements are established, a review of the associated process and its related facilities enables identification of strategic monitoring locations and development of a conceptual system design. The detailed design effort results in the definition of detection components as well as the supporting communications network and data management scheme. The data analyses then enables a coherent display of the knowledge generated during the monitoring effort. The resultant knowledge is then compared to the original system objectives to ensure that the design adequately addresses the fundamental principles stated in the policy agreements. Implementation of this design methodology will ensure that comprehensive unattended monitoring system designs provide appropriate answers to those critical questions imposed by specific agreements or regulations. This paper describes the main features of the methodology and discusses how it can be applied in real world situations.

  11. Design methodology of Dutch banknotes

    Science.gov (United States)

    de Heij, Hans A. M.

    2000-04-01

    Since the introduction of a design methodology for Dutch banknotes, the quality of Dutch paper currency has improved in more than one way. The methodology is question provides for (i) a design policy, which helps fix clear objectives; (ii) design management, to ensure a smooth cooperation between the graphic designer, printer, papermaker an central bank, (iii) a program of requirements, a banknote development guideline for all parties involved. This systematic approach enables an objective selection of design proposals, including security features. Furthermore, the project manager obtains regular feedback from the public by conducting market surveys. Each new design of a Netherlands Guilder banknote issued by the Nederlandsche Bank of the past 50 years has been an improvement on its predecessor in terms of value recognition, security and durability.

  12. Ultra wideband antennas design, methodologies, and performance

    CERN Document Server

    Galvan-Tejada, Giselle M; Jardón Aguilar, Hildeberto

    2015-01-01

    Ultra Wideband Antennas: Design, Methodologies, and Performance presents the current state of the art of ultra wideband (UWB) antennas, from theory specific for these radiators to guidelines for the design of omnidirectional and directional UWB antennas. Offering a comprehensive overview of the latest UWB antenna research and development, this book:Discusses the developed theory for UWB antennas in frequency and time domainsDelivers a brief exposition of numerical methods for electromagnetics oriented to antennasDescribes solid-planar equivalen

  13. Waste Package Design Methodology Report

    Energy Technology Data Exchange (ETDEWEB)

    D.A. Brownson

    2001-09-28

    The objective of this report is to describe the analytical methods and processes used by the Waste Package Design Section to establish the integrity of the various waste package designs, the emplacement pallet, and the drip shield. The scope of this report shall be the methodology used in criticality, risk-informed, shielding, source term, structural, and thermal analyses. The basic features and appropriateness of the methods are illustrated, and the processes are defined whereby input values and assumptions flow through the application of those methods to obtain designs that ensure defense-in-depth as well as satisfy requirements on system performance. Such requirements include those imposed by federal regulation, from both the U.S. Department of Energy (DOE) and U.S. Nuclear Regulatory Commission (NRC), and those imposed by the Yucca Mountain Project to meet repository performance goals. The report is to be used, in part, to describe the waste package design methods and techniques to be used for producing input to the License Application Report.

  14. Ship design methodologies of preliminary design

    CERN Document Server

    Papanikolaou, Apostolos

    2014-01-01

    This book deals with ship design and in particular with methodologies of the preliminary design of ships. The book is complemented by a basic bibliography and five appendices with useful updated charts for the selection of the main dimensions and other basic characteristics of different types of ships (Appendix A), the determination of hull form  from the data of systematic hull form series (Appendix B), the detailed description of the relational method for the preliminary estimation of ship weights (Appendix C), a brief review of the historical evolution of shipbuilding science and technology from the prehistoric era to date (Appendix D) and finally a historical review of regulatory developments of ship's damage stability to date (Appendix E).  The book can be used as textbook for ship design courses or as additional reading for university or college students of naval architecture courses and related disciplines; it may also serve as a reference book for naval architects, practicing engineers of rel...

  15. Reliability based design optimization: Formulations and methodologies

    Science.gov (United States)

    Agarwal, Harish

    Modern products ranging from simple components to complex systems should be designed to be optimal and reliable. The challenge of modern engineering is to ensure that manufacturing costs are reduced and design cycle times are minimized while achieving requirements for performance and reliability. If the market for the product is competitive, improved quality and reliability can generate very strong competitive advantages. Simulation based design plays an important role in designing almost any kind of automotive, aerospace, and consumer products under these competitive conditions. Single discipline simulations used for analysis are being coupled together to create complex coupled simulation tools. This investigation focuses on the development of efficient and robust methodologies for reliability based design optimization in a simulation based design environment. Original contributions of this research are the development of a novel efficient and robust unilevel methodology for reliability based design optimization, the development of an innovative decoupled reliability based design optimization methodology, the application of homotopy techniques in unilevel reliability based design optimization methodology, and the development of a new framework for reliability based design optimization under epistemic uncertainty. The unilevel methodology for reliability based design optimization is shown to be mathematically equivalent to the traditional nested formulation. Numerical test problems show that the unilevel methodology can reduce computational cost by at least 50% as compared to the nested approach. The decoupled reliability based design optimization methodology is an approximate technique to obtain consistent reliable designs at lesser computational expense. Test problems show that the methodology is computationally efficient compared to the nested approach. A framework for performing reliability based design optimization under epistemic uncertainty is also developed

  16. Design Methodologies: Industrial and Educational Applications

    NARCIS (Netherlands)

    Tomiyama, T.; Gul, P.; Jin, Y.; Lutters, Diederick; Kind, Ch.; Kimura, F.

    2009-01-01

    The field of Design Theory and Methodology has a rich collection of research results that has been taught at educational institutions as well as applied to design practices. First, this keynote paper describes some methods to classify them. It then illustrates individual theories and methodologies

  17. Design methodologies: Industrial and educational applications

    NARCIS (Netherlands)

    Tomiyama, T.; Gul, P.; Jin, Y.; Lutters, D.; Kind, Ch.; Kimura, F.

    2009-01-01

    The field of Design Theory and Methodology has a rich collection of research results that has been taught at educational institutions as well as applied to design practices. First, this keynote paper describes some methods to classify them. It then illustrates individual theories and methodologies f

  18. Design of formulated products: a systematic methodology

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul; Ng, K.M.

    2011-01-01

    -based computer-aided methodology for design and verification of a class of chemical-based products (liquid formulations) is presented. This methodology is part of an integrated three-stage approach for design/verification of liquid formulations where stage-1 generates a list of feasible product candidates and....../or verifies a specified set through a sequence of predefined activities (work-flow). Stage-2 and stage-3 (not presented here) deal with the planning and execution of experiments, for product validation. Four case studies have been developed to test the methodology. The computer-aided design (stage-1...

  19. Design methodology for innovative roofs

    NARCIS (Netherlands)

    Quanjel, E.M.C.J.; Zeiler, W.; Trum, H.M.G.J.

    2006-01-01

    Traditional roofs have primary, passive, functions such as protection against rain, wind, snow etc.. Nowadays, roofs are increasingly used as preferred location for additional functions such as photovoltaic systems, roof lights and safety devices. New approaches, on designing as well as assembling t

  20. A design methodology for unattended monitoring systems

    Energy Technology Data Exchange (ETDEWEB)

    SMITH,JAMES D.; DELAND,SHARON M.

    2000-03-01

    The authors presented a high-level methodology for the design of unattended monitoring systems, focusing on a system to detect diversion of nuclear materials from a storage facility. The methodology is composed of seven, interrelated analyses: Facility Analysis, Vulnerability Analysis, Threat Assessment, Scenario Assessment, Design Analysis, Conceptual Design, and Performance Assessment. The design of the monitoring system is iteratively improved until it meets a set of pre-established performance criteria. The methodology presented here is based on other, well-established system analysis methodologies and hence they believe it can be adapted to other verification or compliance applications. In order to make this approach more generic, however, there needs to be more work on techniques for establishing evaluation criteria and associated performance metrics. They found that defining general-purpose evaluation criteria for verifying compliance with international agreements was a significant undertaking in itself. They finally focused on diversion of nuclear material in order to simplify the problem so that they could work out an overall approach for the design methodology. However, general guidelines for the development of evaluation criteria are critical for a general-purpose methodology. A poor choice in evaluation criteria could result in a monitoring system design that solves the wrong problem.

  1. A new methodology for hospital design.

    Science.gov (United States)

    Mejia, Ana Maria Silva

    2013-08-01

    According to architect, Ana Maria Silva Mejia, 'a new era for the design of hospitals in Guatemala has arrived', with a considerable growth in interest around good healthcare facility design. Here, in a slightly adapted version of an article, 'A new methodology for design', first published in the IFHE (International Federation of Hospital Engineering) Digest 2012, she reports on the application of a new methodology designed to optimise efficient use of space, and clinical and other adjacencies, in a district hospital in the City of Zacapa. The system has subsequently been successfully applied to a number of other Guatemalan healthcare facilities.

  2. A semi-custom design methodology for design performance optimization

    Institute of Scientific and Technical Information of China (English)

    Dong-ming LV; Pei-yong ZHANG; Dan-dan ZHENG; Xiao-lang YAN; Bo ZHANG; Li QUAN

    2008-01-01

    We present a semi-custom design methodology based on transistor tuning to optimize the design performance.Compared with other transistor tuning approaches, our tuning process takes the cross-talk effect into account and prominently reduces the complexity for circuit simulation and analysis by decomposing the circuit network utilizing graph theory. Furthermore,the incremental placement and routing for the corresponding transistor tuning in conventional approaches is not required in our methodology, which might induce timing graph variation and additional iterations for design convergence. This methodology combines the flexible automated circuit tuning and physical design tools to provide more opportunities for design optimization throughout the design cycle.

  3. Qualitative methodology for efficient food chain design

    NARCIS (Netherlands)

    Apaiah, R.K.; Hendrix, E.M.T.; Meerdink, G.; Linnemann, A.R.

    2005-01-01

    This paper presents a methodology to efficiently design food supply chains. The goals of quality, cost and environmental load are looked at independently of each other. Food chains are made up of links and are designed to deliver a particular product with consumer-specified attributes. These attribu

  4. A passive DC current sensing methodology

    Science.gov (United States)

    Wang, Dong F.; Liu, Huan; Li, Xiaodong; Li, Yang; Xian, Weikang

    2016-10-01

    This paper proposes a method for passive sensing a two-wire DC current without using any cord separator. In this method, a piezoelectric thin-film cantilever with a micro-magnet on its end is positioned near a power cord. The DC current in the power cord induces a magnetic field, which generates a magnetic force acting on the micro-magnet. Consequently, the piezoelectric cantilever is bent and induces an output voltage that is sensitive to small variations of DC currents. A prototype device has been fabricated and experimentally studied. It was found that the initial peak amplitude of the piezoelectric output voltage increases linearly with the DC current value upon "ON-OFF" switching. Compared to the Hall-effect based sensing, this method has the advantages of no need of driving voltage or cord separators even for two-wire appliance cords. Apart from the conventional consumer electronics, this method may have a wide application foreground in the new emerging fields, such as energy vehicles, lithium ion battery, or smart power grid.

  5. Process independent automated sizing methodology for current steering DAC

    Science.gov (United States)

    Vural, R. A.; Kahraman, N.; Erkmen, B.; Yildirim, T.

    2015-10-01

    This study introduces a process independent automated sizing methodology based on general regression neural network (GRNN) for current steering complementary metal-oxide semiconductor (CMOS) digital-to-analog converter (DAC) circuit. The aim is to utilise circuit structures designed with previous process technologies and to synthesise circuit structures for novel process technologies in contrast to other modelling researches that consider a particular process technology. The simulations were performed using ON SEMI 1.5 µm, ON SEMI 0.5 µm and TSMC 0.35 µm technology process parameters. Eventually, a high-dimensional database was developed consisting of transistor sizes of DAC designs and corresponded static specification errors obtained from simulation results. The key point is that the GRNN was trained with the data set including the simulation results of ON-SEMI 1.5 µm and 0.5 µm technology parameters and the test data were constituted with only the simulation results of TSMC 0.35 µm technology parameters that had not been applied to GRNN for training beforehand. The proposed methodology provides the channel lengths and widths of all transistors for a newer technology when the designer sets the numeric values of DAC static output specifications as Differential Non-linearity error, Integral Non-linearity error, monotonicity and gain error as the inputs of the network.

  6. Operator Design Methodology and Application in H.264 Entropy Coding

    Directory of Open Access Journals (Sweden)

    Ziyi Hu

    2010-11-01

    Full Text Available Currently ASIC applications, such as multimedia processing, require shorter time-to-market and lower cost of Non Recurring Engineering (NRE. Also, with the IC manufacturing technology developing continually, from transistor level to logic gate level, the size of design cells in digital circuits is increasing correspondingly. New design methodology is in urgent need to meet the requirement for the developing processing technology and shorter time-to-market in IC industry. This paper proposed the concepts and principles of operator design methodology, then focused on the entropy coding application based on the operators and finally presented the implementation results. The results show that with the proposed methodology, a comparable hardware performance can be obtained against the traditional standard cell based design flow. Furthermore, the design speed can be improved efficiently.

  7. Comparative performance of image fusion methodologies in eddy current testing

    Directory of Open Access Journals (Sweden)

    S. Thirunavukkarasu

    2012-12-01

    Full Text Available Image fusion methodologies have been studied for improving the detectability of eddy current Nondestructive Testing (NDT. Pixel level image fusion has been performed on C-scan eddy current images of a sub-surface defect at two different frequencies. Multi-resolution analysis based Laplacian pyramid and wavelet fusion methodologies, statistical inference based Bayesian fusion and Principal Component Analysis (PCA based fusion methodologies have been studied towards improving the detectability of defects. The performance of the fusion methodologies has been compared using image metrics such as SNR and entropy. Bayesian based fusion methodology has shown better performance as compared to other methodologies with 33.75 dB improvement in the SNR and an improvement of 3.22 in the entropy.

  8. System-level design methodologies for telecommunication

    CERN Document Server

    Sklavos, Nicolas; Goehringer, Diana; Kitsos, Paris

    2013-01-01

    This book provides a comprehensive overview of modern networks design, from specifications and modeling to implementations and test procedures, including the design and implementation of modern networks on chip, in both wireless and mobile applications.  Topical coverage includes algorithms and methodologies, telecommunications, hardware (including networks on chip), security and privacy, wireless and mobile networks and a variety of modern applications, such as VoLTE and the internet of things.

  9. Waste Package Component Design Methodology Report

    Energy Technology Data Exchange (ETDEWEB)

    D.C. Mecham

    2004-07-12

    This Executive Summary provides an overview of the methodology being used by the Yucca Mountain Project (YMP) to design waste packages and ancillary components. This summary information is intended for readers with general interest, but also provides technical readers a general framework surrounding a variety of technical details provided in the main body of the report. The purpose of this report is to document and ensure appropriate design methods are used in the design of waste packages and ancillary components (the drip shields and emplacement pallets). The methodology includes identification of necessary design inputs, justification of design assumptions, and use of appropriate analysis methods, and computational tools. This design work is subject to ''Quality Assurance Requirements and Description''. The document is primarily intended for internal use and technical guidance for a variety of design activities. It is recognized that a wide audience including project management, the U.S. Department of Energy (DOE), the U.S. Nuclear Regulatory Commission, and others are interested to various levels of detail in the design methods and therefore covers a wide range of topics at varying levels of detail. Due to the preliminary nature of the design, readers can expect to encounter varied levels of detail in the body of the report. It is expected that technical information used as input to design documents will be verified and taken from the latest versions of reference sources given herein. This revision of the methodology report has evolved with changes in the waste package, drip shield, and emplacement pallet designs over many years and may be further revised as the design is finalized. Different components and analyses are at different stages of development. Some parts of the report are detailed, while other less detailed parts are likely to undergo further refinement. The design methodology is intended to provide designs that satisfy the safety

  10. Design Science Methodology Applied to a Chemical Surveillance Tool

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Zhuanyi; Han, Kyungsik; Charles-Smith, Lauren E.; Henry, Michael J.

    2017-05-11

    Public health surveillance systems gain significant benefits from integrating existing early incident detection systems,supported by closed data sources, with open source data.However, identifying potential alerting incidents relies on finding accurate, reliable sources and presenting the high volume of data in a way that increases analysts work efficiency; a challenge for any system that leverages open source data. In this paper, we present the design concept and the applied design science research methodology of ChemVeillance, a chemical analyst surveillance system.Our work portrays a system design and approach that translates theoretical methodology into practice creating a powerful surveillance system built for specific use cases.Researchers, designers, developers, and related professionals in the health surveillance community can build upon the principles and methodology described here to enhance and broaden current surveillance systems leading to improved situational awareness based on a robust integrated early warning system.

  11. Designing a Test Fixture with DFSS Methodology

    Directory of Open Access Journals (Sweden)

    Charles G. Kibbe

    2016-01-01

    Full Text Available This paper addresses the application of Design for Six Sigma (DFSS methodology to the design of a marine riser joint hydraulic line test fixture. The original test fixture was evaluated using Value Steam Mapping (VSM and appropriate Lean design tools such as 3D Modeling and Finite Element Analysis (FEA. A new test fixture was developed which resulted in improving the process cycle efficiency for the test from 25% to 50% percent, leading to a 50% reduction in test cost. Handling of the new test fixture is greatly improved as compared to the original fixture.

  12. An Analysis of Software Design Methodologies

    Science.gov (United States)

    1979-08-01

    Technical Report 401-, # "AN ANALYSIS OF SOFTWARE DESIGN METHODOLOGIES H. Rudy Ramsey, Michael E. Atwood , and Gary D. Campbell Science...H. Rudy Ramsey, Michael E. Atwood , and Gary D. Campbell Science Applications, Incorporated Submitted by: Edgar M. Johnson, Chief HUMAN FACTORS...expressed by members ot the Integrated Software Research and Development Working Group (ISRAD). The authors are indebted to Martha Cichelli, Margaret

  13. Control/structure interaction design methodology

    Science.gov (United States)

    Briggs, Hugh C.; Layman, William E.

    1989-01-01

    The Control Structure Interaction Program is a technology development program for spacecraft that exhibit interactions between the control system and structural dynamics. The program objectives include development and verification of new design concepts (such as active structure) and new tools (such as a combined structure and control optimization algorithm) and their verification in ground and possibly flight test. The new CSI design methodology is centered around interdisciplinary engineers using new tools that closely integrate structures and controls. Verification is an important CSI theme and analysts will be closely integrated to the CSI Test Bed laboratory. Components, concepts, tools and algorithms will be developed and tested in the lab and in future Shuttle-based flight experiments. The design methodology is summarized in block diagrams depicting the evolution of a spacecraft design and descriptions of analytical capabilities used in the process. The multiyear JPL CSI implementation plan is described along with the essentials of several new tools. A distributed network of computation servers and workstations was designed that will provide a state-of-the-art development base for the CSI technologies.

  14. Advertising Graphic Design: theoretical and methodological foundations

    OpenAIRE

    Antonovych, Y.; Pryshchenko, S.

    2016-01-01

    The article deals with the authors theoretical and methodological foundations to the forming of an actual educational discipline «Ad Graphic Design» as integration of graphic design, advertising and marketing. Basic components of the professionalism of a designer in advertising have been selected taking into account the requirements of modern market: graphic design-foundation, sociological and marketing components. В статье рассмотрены разработанные авторами теоретико-методологические осно...

  15. Minimax Current Density Coil Design

    CERN Document Server

    Poole, Michael; Lopez, Hector Sanchez; Ng, Michael; Crozier, Stuart; 10.1088/0022-3727/43/9/095001

    2010-01-01

    'Coil design' is an inverse problem in which arrangements of wire are designed to generate a prescribed magnetic field when energized with electric current. The design of gradient and shim coils for magnetic resonance imaging (MRI) are important examples of coil design. The magnetic fields that these coils generate are usually required to be both strong and accurate. Other electromagnetic properties of the coils, such as inductance, may be considered in the design process, which becomes an optimization problem. The maximum current density is additionally optimized in this work and the resultant coils are investigated for performance and practicality. Coils with minimax current density were found to exhibit maximally spread wires and may help disperse localized regions of Joule heating. They also produce the highest possible magnetic field strength per unit current for any given surface and wire size. Three different flavours of boundary element method that employ different basis functions (triangular elements...

  16. Research in Green Modularity Design Methodology

    Institute of Scientific and Technical Information of China (English)

    LI Fang-yi; LI Jian-feng; DUAN Guang-hong; ZHANG Hong-chao; XU Jin-yong; MA Kai-ling

    2005-01-01

    Green design and manufacturing is a proactive approach to minimize wastes during a product's design stage, thus preventing future environmental impacts. Current modular design method mainly focuses on productfunctional and manufacturing issues. In this paper,a theoretical scheme of multi-objective modularity analysis for discrete electromechanical product design was proposed. Product physical architecture was represented by a fuzzy graph, where fuzzy relationships contain environmental objectives and influence module formulation. Finally the optimal product modules combining all objectives can be searched by clustering algorithm.

  17. Scalable Multi-core Architectures Design Methodologies and Tools

    CERN Document Server

    Jantsch, Axel

    2012-01-01

    As Moore’s law continues to unfold, two important trends have recently emerged. First, the growth of chip capacity is translated into a corresponding increase of number of cores. Second, the parallalization of the computation and 3D integration technologies lead to distributed memory architectures. This book provides a current snapshot of industrial and academic research, conducted as part of the European FP7 MOSART project, addressing urgent challenges in many-core architectures and application mapping.  It addresses the architectural design of many core chips, memory and data management, power management, design and programming methodologies. It also describes how new techniques have been applied in various industrial case studies. Describes trends towards distributed memory architectures and distributed power management; Integrates Network on Chip with distributed, shared memory architectures; Demonstrates novel design methodologies and frameworks for multi-core design space exploration; Shows how midll...

  18. Methodological Approaches in Conducting Overviews: Current State in HTA Agencies

    Science.gov (United States)

    Pieper, Dawid; Antoine, Sunya-Lee; Morfeld, Jana-Carina; Mathes, Tim; Eikermann, Michaela

    2014-01-01

    Objectives: Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in…

  19. A designerly methodology for software development

    NARCIS (Netherlands)

    Du Bois , E.

    2013-01-01

    This PhD researches the domain of industrial design engineering starting from the strong technological evolutions and changing economic, social and ecological needs. Our current products are not only build from hardware components, but are a complex mix of hardware, software and services (in

  20. A designerly methodology for software development

    NARCIS (Netherlands)

    Du Bois , E.

    2013-01-01

    This PhD researches the domain of industrial design engineering starting from the strong technological evolutions and changing economic, social and ecological needs. Our current products are not only build from hardware components, but are a complex mix of hardware, software and services (in differ

  1. Further validation of bracket pillar design methodology

    CSIR Research Space (South Africa)

    Vieira, F

    1998-07-01

    Full Text Available and geological factors that would be easily measured. GAP 516, the current project, was concerned with the applicability of the above design approach to real mine geometries and has concentrated, therefore, on studying the behaviour of various closely monitored...

  2. Integrating rock mechanics issues with repository design through design process principles and methodology

    Energy Technology Data Exchange (ETDEWEB)

    Bieniawski, Z.T. [Pennsylvania State Univ., University Park, PA (United States)

    1996-04-01

    A good designer needs not only knowledge for designing (technical know-how that is used to generate alternative design solutions) but also must have knowledge about designing (appropriate principles and systematic methodology to follow). Concepts such as {open_quotes}design for manufacture{close_quotes} or {open_quotes}concurrent engineering{close_quotes} are widely used in the industry. In the field of rock engineering, only limited attention has been paid to the design process because design of structures in rock masses presents unique challenges to the designers as a result of the uncertainties inherent in characterization of geologic media. However, a stage has now been reached where we are be able to sufficiently characterize rock masses for engineering purposes and identify the rock mechanics issues involved but are still lacking engineering design principles and methodology to maximize our design performance. This paper discusses the principles and methodology of the engineering design process directed to integrating site characterization activities with design, construction and performance of an underground repository. Using the latest information from the Yucca Mountain Project on geology, rock mechanics and starter tunnel design, the current lack of integration is pointed out and it is shown how rock mechanics issues can be effectively interwoven with repository design through a systematic design process methodology leading to improved repository performance. In essence, the design process is seen as the use of design principles within an integrating design methodology, leading to innovative problem solving. In particular, a new concept of {open_quotes}Design for Constructibility and Performance{close_quotes} is introduced. This is discussed with respect to ten rock mechanics issues identified for repository design and performance.

  3. Mixed-signal methodology guide advanced methodology for AMS IP and SOC design, verification and implementation

    CERN Document Server

    Chen, Jess; Mar, Monte F; Nizic, Mladen; Bailey, Brian

    2012-01-01

    This Book, The Mixed-Signal Methodology Guide: Advanced Methodology For Ams Ip And Soc Design, Verification, And Implementation Provides A Broad Overview Of The Design, Verification And Implementation Methodologies Required For Today's Mixed-Signal Designs. The Book Covers Mixed-Signal Design Trends And Challenges, Abstraction Of Analog Using Behavioral Models, Assertion-Based Metric-Driven Verification Methodology Applied On Analog And Mixed-Signal And Verification Of Low Power Intent In Mixed-Signal Design. It Also Describes Methodology For Physical Implementation In Context Of Concurrent Mixed-Signal Design And For Handling Advanced Node Physical Effects. The Book Contains Many Practical Examples Of Models And Techniques. The Authors Believe It Should Serve As A Reference To Many Analog, Digital And Mixed-Signal Designers, Verification, Physical Implementation Engineers And Managers In Their Pursuit Of Information For A Better Methodology Required To Address The Challenges Of Modern Mixed-Signal Design.

  4. A Systematic Methodology for Design of Emulsion Based Chemical Products

    DEFF Research Database (Denmark)

    Mattei, Michele; Kontogeorgis, Georgios; Gani, Rafiqul

    2012-01-01

    A systematic methodology for emulsion based chemical product design is presented. The methodology employs a model-based product synthesis/design stage and a modelexperiment based further refinement and/or validation stage. In this paper only the first stage is presented. The methodology employs...

  5. A Comprehensive Comparison of Current Operating Reserve Methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Krad, Ibrahim; Ibanez, Eduardo; Gao, Wenzhong

    2016-05-05

    Electric power systems are currently experiencing a paradigm shift from a traditionally static system to a system that is becoming increasingly more dynamic and variable. Emerging technologies are forcing power system operators to adapt to their performance characteristics. These technologies, such as distributed generation and energy storage systems, have changed the traditional idea of a distribution system with power flowing in one direction into a distribution system with bidirectional flows. Variable generation, in the form of wind and solar generation, also increases the variability and uncertainty in the system. As such, power system operators are revisiting the ways in which they treat this evolving power system, namely by modifying their operating reserve methodologies. This paper intends to show an in-depth analysis on different operating reserve methodologies and investigate their impacts on power system reliability and economic efficiency.

  6. The New Embedded System Design Methodology For Improving Design Process Performance

    CERN Document Server

    Abdurohman, Maman; Sutikno, Sarwono; Sasongko, Arif

    2010-01-01

    Time-to-market pressure and productivity gap force vendors and researchers to improve embedded system design methodology. Current used design method, Register Transfer Level (RTL), is no longer be adequate to comply with embedded system design necessity. It needs a new methodology for facing the lack of RTL. In this paper, a new methodology of hardware embedded system modeling process is designed for improving design process performance using Transaction Level Modeling (TLM). TLM is a higher abstraction design concept model above RTL model. Parameters measured include design process time and accuracy of design. For implementing RTL model used Avalon and Wishbone buses, both are System on Chip bus. Performance improvement measured by comparing TLM and RTL model process. The experiment results show performance improvements for Avalon RTL using new design methodology are 1,03 for 3-tiers, 1,47 for 4-tiers and 1,69 for 5-tiers. Performance improvements for Wishbone RTL are 1,12 for 3-tiers, 1,17 for 4-tiers and 1...

  7. Development and implementation of rotorcraft preliminary design methodology using multidisciplinary design optimization

    Science.gov (United States)

    Khalid, Adeel Syed

    information from one discipline to another in a collaborative manner. Several disciplinary and system level optimization problems are solved. After all the constraints of a multidisciplinary problem have been satisfied and an optimal design has been obtained, it is compared with the initial baseline, using the earlier developed OEC, to measure the level of improvement achieved. Finally a digital preliminary design is proposed. The proposed design methodology provides an automated design framework, facilitates parallel design by removing disciplinary interdependency, current and updated information is made available to all disciplines at all times of the design through a central collaborative repository, overall design time is reduced and an optimized design is achieved.

  8. A Design Methodology For Industrial Vision Systems

    Science.gov (United States)

    Batchelor, B. G.; Waltz, F. M.; Snyder, M. A.

    1988-11-01

    The cost of design, rather than that of target system hardware, represents the principal factor inhibiting the adoption of machine vision systems by manufacturing industry. To reduce design costs to a minimum, a number of software and hardware aids have been developed or are currently being built by the authors. These design aids are as follows: a. An expert system for giving advice about which image acquisition techniques (i.e. lighting/viewing techniques) might be appropriate in a given situation. b. A program to assist in the selection and setup of camera lenses. c. A rich repertoire of image processing procedures, integrated with the Al language Prolog. This combination (called ProVision) provides a facility for experimenting with intelligent image processing techniques and is intended to allow rapid prototyping of algorithms and/or heuristics. d. Fast image processing hardware, capable of implementing commands in the ProVision language. The speed of operation of this equipment is sufficiently high for it to be used, without modification, in many industrial applications. Where this is not possible, even higher execution speed may be achieved by adding extra modules to the processing hardware. In this way, it is possible to trade speed against the cost of the target system hardware. New and faster implementations of a given algorithm/heuristic can usually be achieved with the expenditure of only a small effort. Throughout this article, the emphasis is on designing an industrial vision system in a smooth and effortless manner. In order to illustrate our main thesis that the design of industrial vision systems can be made very much easier through the use of suitable utilities, the article concludes with a discussion of a case study: the dissection of tiny plants using a visually controlled robot.

  9. Surface design methodology - challenge the steel

    Science.gov (United States)

    Bergman, M.; Rosen, B.-G.; Eriksson, L.; Anderberg, C.

    2014-03-01

    The way a product or material is experienced by its user could be different depending on the scenario. It is also well known that different materials and surfaces are used for different purposes. When optimizing materials and surface roughness for a certain something with the intention to improve a product, it is important to obtain not only the physical requirements, but also the user experience and expectations. Laws and requirements of the materials and the surface function, but also the conservative way of thinking about materials and colours characterize the design of medical equipment. The purpose of this paper is to link the technical- and customer requirements of current materials and surface textures in medical environments. By focusing on parts of the theory of Kansei Engineering, improvements of the companys' products are possible. The idea is to find correlations between desired experience or "feeling" for a product, -customer requirements, functional requirements, and product geometrical properties -design parameters, to be implemented on new improved products. To be able to find new materials with the same (or better) technical requirements but a higher level of user stimulation, the current material (stainless steel) and its surface (brushed textures) was used as a reference. The usage of focus groups of experts at the manufacturer lead to a selection of twelve possible new materials for investigation in the project. In collaboration with the topical company for this project, three new materials that fulfil the requirements -easy to clean and anti-bacterial came to be in focus for further investigation in regard to a new design of a washer-disinfector for medical equipment using the Kansei based Clean ability approach CAA.

  10. Towards an Airframe Noise Prediction Methodology: Survey of Current Approaches

    Science.gov (United States)

    Farassat, Fereidoun; Casper, Jay H.

    2006-01-01

    In this paper, we present a critical survey of the current airframe noise (AFN) prediction methodologies. Four methodologies are recognized. These are the fully analytic method, CFD combined with the acoustic analogy, the semi-empirical method and fully numerical method. It is argued that for the immediate need of the aircraft industry, the semi-empirical method based on recent high quality acoustic database is the best available method. The method based on CFD and the Ffowcs William- Hawkings (FW-H) equation with penetrable data surface (FW-Hpds ) has advanced considerably and much experience has been gained in its use. However, more research is needed in the near future particularly in the area of turbulence simulation. The fully numerical method will take longer to reach maturity. Based on the current trends, it is predicted that this method will eventually develop into the method of choice. Both the turbulence simulation and propagation methods need to develop more for this method to become useful. Nonetheless, the authors propose that the method based on a combination of numerical and analytical techniques, e.g., CFD combined with FW-H equation, should also be worked on. In this effort, the current symbolic algebra software will allow more analytical approaches to be incorporated into AFN prediction methods.

  11. Methodology for Preliminary Design of Electrical Microgrids

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Richard P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Stamp, Jason E. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Eddy, John P. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Henry, Jordan M [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Munoz-Ramos, Karina [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Abdallah, Tarek [U.S. Army Corps of Engineers, Washington, DC (United States)

    2015-09-30

    Many critical loads rely on simple backup generation to provide electricity in the event of a power outage. An Energy Surety Microgrid TM can protect against outages caused by single generator failures to improve reliability. An ESM will also provide a host of other benefits, including integration of renewable energy, fuel optimization, and maximizing the value of energy storage. The ESM concept includes a categorization for microgrid value proposi- tions, and quantifies how the investment can be justified during either grid-connected or utility outage conditions. In contrast with many approaches, the ESM approach explic- itly sets requirements based on unlikely extreme conditions, including the need to protect against determined cyber adversaries. During the United States (US) Department of Defense (DOD)/Department of Energy (DOE) Smart Power Infrastructure Demonstration for Energy Reliability and Security (SPIDERS) effort, the ESM methodology was successfully used to develop the preliminary designs, which direct supported the contracting, construction, and testing for three military bases. Acknowledgements Sandia National Laboratories and the SPIDERS technical team would like to acknowledge the following for help in the project: * Mike Hightower, who has been the key driving force for Energy Surety Microgrids * Juan Torres and Abbas Akhil, who developed the concept of microgrids for military installations * Merrill Smith, U.S. Department of Energy SPIDERS Program Manager * Ross Roley and Rich Trundy from U.S. Pacific Command * Bill Waugaman and Bill Beary from U.S. Northern Command * Melanie Johnson and Harold Sanborn of the U.S. Army Corps of Engineers Construc- tion Engineering Research Laboratory * Experts from the National Renewable Energy Laboratory, Idaho National Laboratory, Oak Ridge National Laboratory, and Pacific Northwest National Laboratory

  12. A Rigorous Methodology for Analyzing and Designing Plug-Ins

    DEFF Research Database (Denmark)

    Fasie, Marieta V.; Haxthausen, Anne Elisabeth; Kiniry, Joseph

    2013-01-01

    . This paper addresses these problems by describing a rigorous methodology for analyzing and designing plug-ins. The methodology is grounded in the Extended Business Object Notation (EBON) and covers informal analysis and design of features, GUI, actions, and scenarios, formal architecture design, including...... behavioral semantics, and validation. The methodology is illustrated via a case study whose focus is an Eclipse environment for the RAISE formal method's tool suite....

  13. A Design Methodology for Computer Security Testing

    OpenAIRE

    Ramilli, Marco

    2013-01-01

    The field of "computer security" is often considered something in between Art and Science. This is partly due to the lack of widely agreed and standardized methodologies to evaluate the degree of the security of a system. This dissertation intends to contribute to this area by investigating the most common security testing strategies applied nowadays and by proposing an enhanced methodology that may be effectively applied to different threat scenarios with the same degree of effectiveness. ...

  14. A design methodology for cross flow water turbines

    Energy Technology Data Exchange (ETDEWEB)

    Zanette, J.; Imbault, D.; Tourabi, A. [Laboratoire Sols, Solides, Structures - Risques (3S-R) Domaine Universitaire, B.P. 53, 38041 Grenoble Cedex 9 (France)

    2010-05-15

    This contribution deals with the design of cross flow water turbines. The mechanical stress sustained by the blades depends on the basic geometrical specifications of the cross flow water turbine, its rotational speed, the exact geometry of the blades and the velocity of the upstream water current. During the operation, the blades are submitted to severe cyclic loadings generated by pressure field's variation as function of angular position. This paper proposes a simplified design methodology for structural analysis of cross flow water turbine blades, with quite low computational time. A new trapezoidal-bladed turbine obtained from this method promises to be more efficient than the classical designs. Its most distinctive characteristic is a variable profiled cross-section area, which should significantly reduce the intensity of cyclic loadings in the material and improve the turbine's durability. The advantages of this new geometry will be compared with three other geometries based on NACA0018 hydrofoil. (author)

  15. 大容量永磁饱和型故障限流器参数设计与优化%Parameter Design and Optimization Methodology for Large Capacity Applications of Permanent-magnet-biased Saturation Based Fault Current Limiter

    Institute of Scientific and Technical Information of China (English)

    邹亮; 李庆民; 刘洪顺; 张黎

    2011-01-01

    A straight-line type topology was employed for permanent-magnet-biased saturation based fault current limiter (PMFCL) to meet large capacity application requirements. By virtue of three basic variables of saturation depth ratio, inductance ratio and inductance sum, an algorithm for structural parameters design was established on the basis of equivalent magnetic circuit method. Through analysis of the iron-core's operational points, the optimization of the structural parameters was equivalently transformed to optimization of the three independent variables, which can also be considered as the optimization of three key points on the I-Be curve of iron-core. A solid foundation for optimal structural parameters was laid in view of all of the above work. The parameter optimization algorithm was applied to an actual case study in 110 kV system, and a magnetic field-circuit coupled simulation model was created with Maxwell-2D regarding the novel PMFCL topology, which verified the effectiveness of the proposed methodology and the optimized results.%为适应大容量应用需求,针对一种直线式永磁饱和型故障限流器(permanent-magnet-biased saturation based fault current limiter,PMFCL)磁拓扑结构,基于等效磁路法建立了以饱和深度比、电感比与电感和为基本变量的结构参数设计算法,并通过分析铁心上工作点的变化规律,将PMFCL结构参数优化转化为对3个独立变量的优化,即对铁心I-Be曲线上3个关键点的优化问题,为获得最优结构参数奠定了算法基础.将参数优化算法应用于110 kV系统设计实例,并基于Maxwell-2D软件建立了直线式PMFCL的场一路耦合仿真模型,验证了算法及优化结构参数的有效性.

  16. Aircraft conceptual design - an adaptable parametric sizing methodology

    Science.gov (United States)

    Coleman, Gary John, Jr.

    Aerospace is a maturing industry with successful and refined baselines which work well for traditional baseline missions, markets and technologies. However, when new markets (space tourism) or new constrains (environmental) or new technologies (composite, natural laminar flow) emerge, the conventional solution is not necessarily best for the new situation. Which begs the question "how does a design team quickly screen and compare novel solutions to conventional solutions for new aerospace challenges?" The answer is rapid and flexible conceptual design Parametric Sizing. In the product design life-cycle, parametric sizing is the first step in screening the total vehicle in terms of mission, configuration and technology to quickly assess first order design and mission sensitivities. During this phase, various missions and technologies are assessed. During this phase, the designer is identifying design solutions of concepts and configurations to meet combinations of mission and technology. This research undertaking contributes the state-of-the-art in aircraft parametric sizing through (1) development of a dedicated conceptual design process and disciplinary methods library, (2) development of a novel and robust parametric sizing process based on 'best-practice' approaches found in the process and disciplinary methods library, and (3) application of the parametric sizing process to a variety of design missions (transonic, supersonic and hypersonic transports), different configurations (tail-aft, blended wing body, strut-braced wing, hypersonic blended bodies, etc.), and different technologies (composite, natural laminar flow, thrust vectored control, etc.), in order to demonstrate the robustness of the methodology and unearth first-order design sensitivities to current and future aerospace design problems. This research undertaking demonstrates the importance of this early design step in selecting the correct combination of mission, technologies and configuration to

  17. Research on object-oriented SOC design methodology

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The growing complexity of System on Chip (SOC) requires a system level specification and design approach. High-level languages such as C+ +/SystemC can play multiple roles in system design as target languages. There are many practical problems in the application of object-oriented methods for this goal. Based on the analysis of traditional and system-level design methodology, a new object-oriented SOC design methodology with object-oriented design patterns is proposed, which emphasizes high-level design and verification. Aiming at the final goal of developing design patterns specific to SOC design, the reuse of design patterns in SOC systems and the capability of new SOC design patterns are discussed. With the illustration of some concrete examples of SOC design patterns, the application of object-oriented design methodology in the SOC design process is presented.

  18. The design and methodology of premature ejaculation interventional studies.

    Science.gov (United States)

    McMahon, Chris G

    2016-08-01

    Large well-designed clinical efficacy and safety randomized clinical trials (RCTs) are required to achieve regulatory approval of new drug treatments. The objective of this article is to make recommendations for the criteria for defining and selecting the clinical trial study population, design and efficacy outcomes measures which comprise ideal premature ejaculation (PE) interventional trial methodology. Data on clinical trial design, epidemiology, definitions, dimensions and psychological impact of PE was reviewed, critiqued and incorporated into a series of recommendations for standardisation of PE clinical trial design, outcome measures and reporting using the principles of evidence based medicine. Data from PE interventional studies are only reliable, interpretable and capable of being generalised to patients with PE, when study populations are defined by the International Society for Sexual Medicine (ISSM) multivariate definition of PE. PE intervention trials should employ a double-blind RCT methodology and include placebo control, active standard drug control, and/or dose comparison trials. Ejaculatory latency time (ELT) and subject/partner outcome measures of control, personal/partner/relationship distress and other study-specific outcome measures should be used as outcome measures. There is currently no published literature which identifies a clinically significant threshold response to intervention. The ISSM definition of PE reflects the contemporary understanding of PE and represents the state-of-the-art multi-dimensional definition of PE and is recommended as the basis of diagnosis of PE for all PE clinical trials.

  19. Methodological aspects of systemic designing of foundry plants

    Directory of Open Access Journals (Sweden)

    R. Wrona

    2008-10-01

    Full Text Available An approach is attempted to systematise the systemic research. A set of hypotheses are formulated, defining how a conceptual design of afoundry plant should be developed and improved when it is investigated as a system. The methodology aims to eliminate the particular approach to design to be replaced by integral design. The need of integral design seems a logical consequence of a transition from taskoriented design to situational design. The methodology outlined here offers an innovative and modern approach to engineering design, particularly in foundry plant design.

  20. Design Evolution and Methodology for Pumpkin Super-Pressure Balloons

    Science.gov (United States)

    Farley, Rodger

    The NASA Ultra Long Duration Balloon (ULDB) program has had many technical development issues discovered and solved along its road to success as a new vehicle. It has the promise of being a sub-satellite, a means to launch up to 2700 kg to 33.5 km altitude for 100 days from a comfortable mid-latitude launch point. Current high-lift long duration ballooning is accomplished out of Antarctica with zero-pressure balloons, which cannot cope with the rigors of diurnal cycles. The ULDB design is still evolving, the product of intense analytical effort, scaled testing, improved manufacturing, and engineering intuition. The past technical problems, in particular the s-cleft deformation, their solutions, future challenges, and the methodology of pumpkin balloon design will generally be described.

  1. Methodology for simulation of geomagnetically induced currents in power systems

    Directory of Open Access Journals (Sweden)

    Boteler David

    2014-07-01

    Full Text Available To assess the geomagnetic hazard to power systems it is useful to be able to simulate the geomagnetically induced currents (GIC that are produced during major geomagnetic disturbances. This paper examines the methodology used in power system analysis and shows how it can be applied to modelling GIC. Electric fields in the area of the power network are used to determine the voltage sources or equivalent current sources in the transmission lines. The power network can be described by a mesh impedance matrix which is combined with the voltage sources to calculate the GIC in each loop. Alternatively the power network can be described by a nodal admittance matrix which is combined with the sum of current sources into each node to calculate the nodal voltages which are then used to calculate the GIC in the transmission lines and GIC flowing to ground at each substation. Practical calculations can be made by superposition of results calculated separately for northward and eastward electric fields. This can be done using magnetic data from a single observatory to calculate an electric field that is a uniform approximation of the field over the area of the power system. It is also shown how the superposition of results can be extended to use data from two observatories: approximating the electric field by a linear variation between the two observatory locations. These calculations provide an efficient method for simulating the GIC that would be produced by historically significant geomagnetic storm events.

  2. Optimal (Solvent) Mixture Design through a Decomposition Based CAMD methodology

    DEFF Research Database (Denmark)

    Achenie, L.; Karunanithi, Arunprakash T.; Gani, Rafiqul

    2004-01-01

    Computer Aided Molecular/Mixture design (CAMD) is one of the most promising techniques for solvent design and selection. A decomposition based CAMD methodology has been formulated where the mixture design problem is solved as a series of molecular and mixture design sub-problems. This approach is...... is able to overcome most of the difficulties associated with the solution of mixture design problems. The new methodology has been illustrated with the help of a case study involving the design of solvent-anti solvent binary mixtures for crystallization of Ibuprofen.......Computer Aided Molecular/Mixture design (CAMD) is one of the most promising techniques for solvent design and selection. A decomposition based CAMD methodology has been formulated where the mixture design problem is solved as a series of molecular and mixture design sub-problems. This approach...

  3. A Review on Software Mining: Current Trends and Methodologies

    Directory of Open Access Journals (Sweden)

    Gurtej Singh Ubhi

    2017-04-01

    Full Text Available With the evolution of Software Mining, it has enabled to play a crucial role in the day to day activities .By empowering the software with the data mining methods it aids to all the software developers and the managers at all the managerial levels to use it as a tool so that the relative software engineering data (in the form of code, design documents, bug reports to visualize the project‟s status of evolution and progress. To add on, further all the mining methods and algorithms help to device the models to develop any fault prone real time system for the real world more prior to the testing phase or the evolution phase. Also , in this review paper it will highlight the different methodologies for software mining along with its extension as a tool for fault tolerance and as well as a bibliography with the special prominence on mining the software engineering information

  4. Autism genetics: Methodological issues and experimental design.

    Science.gov (United States)

    Sacco, Roberto; Lintas, Carla; Persico, Antonio M

    2015-10-01

    Autism is a complex neuropsychiatric disorder of developmental origin, where multiple genetic and environmental factors likely interact resulting in a clinical continuum between "affected" and "unaffected" individuals in the general population. During the last two decades, relevant progress has been made in identifying chromosomal regions and genes in linkage or association with autism, but no single gene has emerged as a major cause of disease in a large number of patients. The purpose of this paper is to discuss specific methodological issues and experimental strategies in autism genetic research, based on fourteen years of experience in patient recruitment and association studies of autism spectrum disorder in Italy.

  5. Overly ambitious: contributions and current status of Q methodology

    NARCIS (Netherlands)

    Kampen, J.K.; Tamas, P.A.

    2014-01-01

    This essay offers a small description of recent contributions and status of Q methodology by means of a review of suggested best practices, a systematic review of practice, and a methodological audit. Both theoretical and empirical study suggest that Q methodology neither delivers its promised

  6. A methodology for integrating sustainability considerations into process design

    OpenAIRE

    Azapagic, A.; Millington, A.; Collett, A

    2006-01-01

    Designing more sustainable processes is one of the key challenges for sustainable development of the chemical industry. This is by no means a trivial task as it requires translating the theoretical principles of sustainable development into design practice. At present, there is no general methodology to guide sustainable process design and almost no practical experience. In an attempt to contribute to this emerging area, this paper proposes a new methodology for integrating sustainability con...

  7. Participant observation, anthropology methodology and design anthropology research inquiry

    DEFF Research Database (Denmark)

    Gunn, Wendy; Buch Løgstrup, Louise

    2014-01-01

    of practice. They do so by combining participant observation, anthropology methodology and design anthropology research inquiry engaging with practice based explorations to understand if methods and methodologies, understood as being central to anthropological inquiry, can be taught to interaction design......Within the design studio, and across multiple field sites, the authors compare involvement of research tools and materials during collaborative processes of designing. Their aim is to trace temporal dimensions (shifts/ movements) of where and when learning takes place along different sites...... their relation with the private end user? What kind of ways can engaging within collaborative processes of designing offer opportunities for both designing and anthropological research inquiry simultaneously?...

  8. Comparative design of structures concepts and methodologies

    CERN Document Server

    Lin, Shaopei

    2016-01-01

    This book presents comparative design as an approach to the conceptual design of structures. Primarily focusing on reasonable structural performance, sustainable development and architectural aesthetics, it features detailed studies of structural performance through the composition and de-composition of these elements for a variety of structures, such as high-rise buildings, long-span crossings and spatial structures. The latter part of the book addresses the theoretical basis and practical implementation of knowledge engineering in structural design, and a case-based fuzzy reasoning method is introduced to illustrate the concept and method of intelligent design. The book is intended for civil engineers, structural designers and architects, as well as senior undergraduate and graduate students in civil engineering and architecture. Shaopei Lin and Zhen Huang are both Professors at the Department of Civil Engineering, Shanghai Jiao Tong University, China.

  9. Methodology and Technology for Design to Cost

    Institute of Scientific and Technical Information of China (English)

    姜华; 曾庆良; 熊光楞

    2001-01-01

    Product cost is one of the most important factors affectingproduct market share. Traditionally, product costs are estimated after they are manufactured. However, in this way, the best opportunity to control product cost is lost. In this paper, a method trying to reduce product cost at the design stage is proposed. This method is called Design to Cost (DTC). According to this method, product structure can be optimized with the application of value engineering and Design for Manufacturing/Assembly (DFMA) criteria in the conceptual stage of product design. During embodiment design, products are evaluated economically on the basis of the product model which includes manufacturing, assembly and test cost information. According to the results, products are redesigned before manufacture, and the production cost is reduced.

  10. Current methodological issues in the economic assessment of personalized medicine.

    Science.gov (United States)

    Annemans, Lieven; Redekop, Ken; Payne, Katherine

    2013-01-01

    There is a need for methodological scrutiny in the economic assessment of personalized medicine. In this article, we present a list of 10 specific issues that we argue pose specific methodological challenges that require careful consideration when designing and conducting robust model-based economic evaluations in the context of personalized medicine. Key issues are related to the correct framing of the research question, interpretation of test results, data collection of medical management options after obtaining test results, and expressing the value of tests. The need to formulate the research question clearly and be explicit and specific about the technology being evaluated is essential because various test kits can have the same purpose and yet differ in predictive value, costs, and relevance to practice and patient populations. The correct reporting of sensitivity/specificity, and especially the false negatives and false positives (which are population dependent), of the investigated tests is also considered as a key element. This requires additional structural complexity to establish the relationship between the test result and the consecutive treatment changes and outcomes. This process involves translating the test characteristics into clinical utility, and therefore outlining the clinical and economic consequences of true and false positives and true and false negatives. Information on treatment patterns and on their costs and outcomes, however, is often lacking, especially for false-positive and false-negative test results. The analysis can even become very complex if different tests are combined or sequentially used. This potential complexity can be handled by explicitly showing how these tests are going to be used in practice and then working with the combined sensitivities and specificities of the tests. Each of these issues leads to a higher degree of uncertainty in economic models designed to assess the added value of personalized medicine compared

  11. A design optimization methodology for Li+ batteries

    Science.gov (United States)

    Golmon, Stephanie; Maute, Kurt; Dunn, Martin L.

    2014-05-01

    Design optimization for functionally graded battery electrodes is shown to improve the usable energy capacity of Li batteries predicted by computational simulations and numerically optimizing the electrode porosities and particle radii. A multi-scale battery model which accounts for nonlinear transient transport processes, electrochemical reactions, and mechanical deformations is used to predict the usable energy storage capacity of the battery over a range of discharge rates. A multi-objective formulation of the design problem is introduced to maximize the usable capacity over a range of discharge rates while limiting the mechanical stresses. The optimization problem is solved via a gradient based optimization. A LiMn2O4 cathode is simulated with a PEO-LiCF3SO3 electrolyte and both a Li Foil (half cell) and LiC6 anode. Studies were performed on both half and full cell configurations resulting in distinctly different optimal electrode designs. The numerical results show that the highest rate discharge drives the simulations and the optimal designs are dominated by Li+ transport rates. The results also suggest that spatially varying electrode porosities and active particle sizes provides an efficient approach to improve the power-to-energy density of Li+ batteries. For the half cell configuration, the optimal design improves the discharge capacity by 29% while for the full cell the discharge capacity was improved 61% relative to an initial design with a uniform electrode structure. Most of the improvement in capacity was due to the spatially varying porosity, with up to 5% of the gains attributed to the particle radii design variables.

  12. Design Study Methodology: Reflections from the Trenches and the Stacks.

    Science.gov (United States)

    Sedlmair, M; Meyer, M; Munzner, T

    2012-12-01

    Design studies are an increasingly popular form of problem-driven visualization research, yet there is little guidance available about how to do them effectively. In this paper we reflect on our combined experience of conducting twenty-one design studies, as well as reading and reviewing many more, and on an extensive literature review of other field work methods and methodologies. Based on this foundation we provide definitions, propose a methodological framework, and provide practical guidance for conducting design studies. We define a design study as a project in which visualization researchers analyze a specific real-world problem faced by domain experts, design a visualization system that supports solving this problem, validate the design, and reflect about lessons learned in order to refine visualization design guidelines. We characterize two axes - a task clarity axis from fuzzy to crisp and an information location axis from the domain expert's head to the computer - and use these axes to reason about design study contributions, their suitability, and uniqueness from other approaches. The proposed methodological framework consists of 9 stages: learn, winnow, cast, discover, design, implement, deploy, reflect, and write. For each stage we provide practical guidance and outline potential pitfalls. We also conducted an extensive literature survey of related methodological approaches that involve a significant amount of qualitative field work, and compare design study methodology to that of ethnography, grounded theory, and action research.

  13. Methodological Innovation in Practice-Based Design Doctorates

    Directory of Open Access Journals (Sweden)

    Joyce S. R. Yee

    2010-01-01

    Full Text Available This article presents a selective review of recent design PhDs that identify and analyse the methodological innovation that is occurring in the field, in order to inform future provision of research training. Six recently completed design PhDs are used to highlight possible philosophical and practical models that can be adopted by future PhD students in design. Four characteristics were found in design PhD methodology: innovations in the format and structure of the thesis, a pick-and-mix approach to research design, situating practice in the inquiry, and the validation of visual analysis. The article concludes by offering suggestions on how research training can be improved. By being aware of recent methodological innovations in the field, design educators will be better informed when developing resources for future design doctoral candidates and assisting supervision teams in developing a more informed and flexible approach to practice-based research.

  14. A methodology for creating ontologies for engineering design

    DEFF Research Database (Denmark)

    Ahmed, Saeema; Kim, Sanghee; Wallace, Ken

    2005-01-01

    This paper describes a methodology for developing ontologies for engineering design. The methodology combines a number of methods from social science and computer science, together with taxonomies developed in the field of engineering design. A case study is used throughout the paper focusing upon...... the use of an ontology for searching, indexing and retrieving of engineering knowledge. An ontology for indexing design knowledge can assist the users to formulate their queries when searching for engineering design knowledge. The root concepts of the ontology were elicited from engineering designers...

  15. The methodology of database design in organization management systems

    Science.gov (United States)

    Chudinov, I. L.; Osipova, V. V.; Bobrova, Y. V.

    2017-01-01

    The paper describes the unified methodology of database design for management information systems. Designing the conceptual information model for the domain area is the most important and labor-intensive stage in database design. Basing on the proposed integrated approach to design, the conceptual information model, the main principles of developing the relation databases are provided and user’s information needs are considered. According to the methodology, the process of designing the conceptual information model includes three basic stages, which are defined in detail. Finally, the article describes the process of performing the results of analyzing user’s information needs and the rationale for use of classifiers.

  16. Ceramic design methodology and the AGT-101

    Energy Technology Data Exchange (ETDEWEB)

    Boyd, G.L.; Carruthers, W.D.; Evershed, R.J.; Kidwell, J.R.

    1985-03-01

    The Garrett/Ford Advanced Gas Turbine (AGT101) technology project has made significant progress in the areas of ceramic component design, analysis, and test evaluation using an iterative approach. Design stress limits are being defined for state-of-the-art fine ceramics with good correlation between analytical predictions and empirical results. Recent tests in both rigs and engines are demonstrating the feasibility of high temperature/strength ceramic materials in the gas turbine environment. Component transient stress fields are being defined providing the data base for lower stress/longer life component design. Thermally induced transient stresses to 220 MPa (32 ksi) in reaction bonded silicon nitride (RBSN), 310 Mpa (45 ksi) in sintered alpha silicon carbide (SASC), and 345 MPa (50 ksi) in sintered silicon nitride (SSN) have been successfully demonstrated in AGT101 component screening and qualification test rigs.

  17. Modeling and Architectural Design in Agile Development Methodologies

    NARCIS (Netherlands)

    Stojanovic, Z.; Dahanayake, A.; Sol, H

    2003-01-01

    Agile Development Methodologies have been designed to address the problem of delivering high-quality software on time under constantly and rapidly changing requirements in business and IT environments. Agile development processes are characterized by extensive coding practice, intensive communicatio

  18. Design Methodology for Multiple Microcomputer Architectures.

    Science.gov (United States)

    1982-07-01

    multimicro design knowledge is true both in industry and in university environments. In the industrial environment, it reduces productivity and increases...Real-Time Processor Problems," Proc. of ELECTRO-81 Tercer Seminario de Ingenieria Electronica , Nov. 9-13, 1981. 14 1981 "D Flip/Flop Substracts

  19. The importance of robust design methodology

    DEFF Research Database (Denmark)

    Eifler, Tobias; Howard, Thomas J.

    2017-01-01

    While a systematic quality strategy is of crucial importance for the success of manufacturing companies, the universal applicability and effectiveness of implemented quality management practices were called into question by a number of major product recalls in recent years. This article seeks...... to illustrate how already simple analyses and early stage design methods can help to better understand one of the potential reasons for these failures, namely the variation inherent in manufacturing, assembly, and use processes. Usually thoroughly controlled in production, it seems as if particularly the risk...... of unanticipated variation effects remain largely underestimated and thus unaccounted for in design practice, sometimes with disastrous consequences. To foster the awareness of this variation and to illustrate the benefits of its early consideration in product development, this paper reviews one of the most...

  20. Design Methodologies for Secure Embedded Systems

    CERN Document Server

    Biedermann, Alexander

    2011-01-01

    Embedded systems have been almost invisibly pervading our daily lives for several decades. They facilitate smooth operations in avionics, automotive electronics, or telecommunication. New problems arise by the increasing employment, interconnection, and communication of embedded systems in heterogeneous environments: How secure are these embedded systems against attacks or breakdowns? Therefore, how can embedded systems be designed to be more secure? And how can embedded systems autonomically react to threats? Facing these questions, Sorin A. Huss is significantly involved in the exploration o

  1. A design methodology for portable software on parallel computers

    Science.gov (United States)

    Nicol, David M.; Miller, Keith W.; Chrisman, Dan A.

    1993-01-01

    This final report for research that was supported by grant number NAG-1-995 documents our progress in addressing two difficulties in parallel programming. The first difficulty is developing software that will execute quickly on a parallel computer. The second difficulty is transporting software between dissimilar parallel computers. In general, we expect that more hardware-specific information will be included in software designs for parallel computers than in designs for sequential computers. This inclusion is an instance of portability being sacrificed for high performance. New parallel computers are being introduced frequently. Trying to keep one's software on the current high performance hardware, a software developer almost continually faces yet another expensive software transportation. The problem of the proposed research is to create a design methodology that helps designers to more precisely control both portability and hardware-specific programming details. The proposed research emphasizes programming for scientific applications. We completed our study of the parallelizability of a subsystem of the NASA Earth Radiation Budget Experiment (ERBE) data processing system. This work is summarized in section two. A more detailed description is provided in Appendix A ('Programming Practices to Support Eventual Parallelism'). Mr. Chrisman, a graduate student, wrote and successfully defended a Ph.D. dissertation proposal which describes our research associated with the issues of software portability and high performance. The list of research tasks are specified in the proposal. The proposal 'A Design Methodology for Portable Software on Parallel Computers' is summarized in section three and is provided in its entirety in Appendix B. We are currently studying a proposed subsystem of the NASA Clouds and the Earth's Radiant Energy System (CERES) data processing system. This software is the proof-of-concept for the Ph.D. dissertation. We have implemented and measured

  2. A methodology for creating ontologies for engineering design

    DEFF Research Database (Denmark)

    Ahmed, Saeema; Kim, S.; Wallace, K.M.

    2007-01-01

    This paper describes a six-stage methodology for developing ontologies for engineering design, together with the research methods and evaluation of each stage. The methodology focuses upon understanding a user's domain models through empirical research. A case study of an ontology for searching......, indexing, and retrieving engineering knowledge is described. The root concepts of the ontology were elicited from engineering designers. Relationships between concepts are extracted as the ontology is populated. The contribution of this research is a methodology to allow researchers. and industry to create...

  3. A New Design Methodology for Composing Complex Digital Systems

    Directory of Open Access Journals (Sweden)

    S.L. Chu

    2013-04-01

    Full Text Available Continuous growth in the use of multimedia applications on portable devices makes the mobile computer systems have an increasing complexity. The functionalities of the used SOC chips and silicon intelligent properties in these portable devices are become complicated and hard to design. Traditional digital circuit designs adopt register transfer level with timing control methodologies, which focus on the datapath composition, timing control of registers, and the functions of combinational circuits. However, the huge amount of control and synchronous signals of the above components are difficult to design and debug. The timing costs of design and verification are increased dramatically. This paper proposed a new design methodology of digital system, called data-oriented methodology, to deal with the above problems, by using Bluespec SystemVerilog HDL and the corresponding tools. Instead of conventional timing-control mechanism, the data-oriented methodology adopts simple handshaking protocol, blocking transferring, and explicitly register/FIFO declaration for communicating between adjacent modules. The designs of FDCT/IDCT and pipelined MIPS-like CPU are adopted to compare the design costs of conventional timing-control and data-oriented methodologies. The chip performance and FPGA proven of these two designs are discussed

  4. Design Methodology and Manufacture of a Microinductor

    CERN Document Server

    Flynn, D

    2008-01-01

    Potential core materials to supersede ferrite in the 0.5-10 MHz frequency range are investigated. The performance of electrodeposited nickel-iron, cobalt-iron-copper alloys and the commercial alloy Vitrovac 6025 have been assessed through their inclusion within a custom-made solenoid microinductor. Although the present inductor, at 500 KHz, achieves 77% power efficiency for 24.7W/cm3 power density, an optimized process predicts a power efficiency of 97% for 30.83W/cm3 power density. The principle issues regarding microinductor design and performance are discussed.

  5. Production systems design : a product oriented approach and methodology

    OpenAIRE

    2008-01-01

    Production systems design is critical to achieving manufacturing performance and objectives. Although generic approaches to this design are available they may not be able to objectively address specific manufacturing configurations. Here it is argued that product oriented manufacturing (POM) organization offers advantages in relation to the function oriented one. Based on this, a methodology specially addressing POM systems design, and prototype of a Computer Aided Design Syste...

  6. Optimal Design and Purposeful Sampling: Complementary Methodologies for Implementation Research.

    Science.gov (United States)

    Duan, Naihua; Bhaumik, Dulal K; Palinkas, Lawrence A; Hoagwood, Kimberly

    2015-09-01

    Optimal design has been an under-utilized methodology. However, it has significant real-world applications, particularly in mixed methods implementation research. We review the concept and demonstrate how it can be used to assess the sensitivity of design decisions and balance competing needs. For observational studies, this methodology enables selection of the most informative study units. For experimental studies, it entails selecting and assigning study units to intervention conditions in the most informative manner. We blend optimal design methods with purposeful sampling to show how these two concepts balance competing needs when there are multiple study aims, a common situation in implementation research.

  7. Topics in expert system design methodologies and tools

    CERN Document Server

    Tasso, C

    1989-01-01

    Expert Systems are so far the most promising achievement of artificial intelligence research. Decision making, planning, design, control, supervision and diagnosis are areas where they are showing great potential. However, the establishment of expert system technology and its actual industrial impact are still limited by the lack of a sound, general and reliable design and construction methodology.This book has a dual purpose: to offer concrete guidelines and tools to the designers of expert systems, and to promote basic and applied research on methodologies and tools. It is a coordinated coll

  8. A methodological approach to designing sewer system control

    DEFF Research Database (Denmark)

    Mollerup, Ane Loft

    for this thesis was therefore the wish for a methodological approach to sewer system control design. Using a case study the following research hypothesis was tested in this thesis: Using classical and modern control theory, a methodological approach can be derived for designing sewer system control. This can aid...... urban drainage planner and other professionals in the planning phase of sewer system con-trol design and effectively contribute to find novel control solution. It was investigated if the established methodology used in classic control the-ory for process control design can be applied meaningfully....... This was not unexpected, since the true potential of having optimisation arises, when a system has many control loops with limit-ing constraints and/or changing prioritisation between them. The results showed that for small sewer systems, where the complexity is limited, it is not necessarily the best option to implement...

  9. PEM Fuel Cells Redesign Using Biomimetic and TRIZ Design Methodologies

    Science.gov (United States)

    Fung, Keith Kin Kei

    Two formal design methodologies, biomimetic design and the Theory of Inventive Problem Solving, TRIZ, were applied to the redesign of a Proton Exchange Membrane (PEM) fuel cell. Proof of concept prototyping was performed on two of the concepts for water management. The liquid water collection with strategically placed wicks concept demonstrated the potential benefits for a fuel cell. Conversely, the periodic flow direction reversal concepts might cause a potential reduction water removal from a fuel cell. The causes of this water removal reduction remain unclear. In additional, three of the concepts generated with biomimetic design were further studied and demonstrated to stimulate more creative ideas in the thermal and water management of fuel cells. The biomimetic design and the TRIZ methodologies were successfully applied to fuel cells and provided different perspectives to the redesign of fuel cells. The methodologies should continue to be used to improve fuel cells.

  10. Methodological Innovation in Practice-Based Design Doctorates

    Science.gov (United States)

    Yee, Joyce S. R.

    2010-01-01

    This article presents a selective review of recent design PhDs that identify and analyse the methodological innovation that is occurring in the field, in order to inform future provision of research training. Six recently completed design PhDs are used to highlight possible philosophical and practical models that can be adopted by future PhD…

  11. Designing for situated knowledge: methodological issues and more

    NARCIS (Netherlands)

    Martens, Rob; De Laat, Maarten; Verjans, Steven

    2017-01-01

    When it comes to the type of complex questions such as how to design for situated knowledge, there is a strong need for suitable research methodology to address such complex and interwoven problems. This problem not only occurs in this context (design for situated knowledge), but is an underlying

  12. Design methodology to enhance high impedance surfaces performances

    Directory of Open Access Journals (Sweden)

    M. Grelier

    2014-04-01

    Full Text Available A methodology is introduced for designing wideband, compact and ultra-thin high impedance surfaces (HIS. A parametric study is carried out to examine the effect of the periodicity on the electromagnetic properties of an HIS. This approach allows designers to reach the best trade-off for HIS performances.

  13. A New Design Methodology for Composing Complex Digital Systems

    Directory of Open Access Journals (Sweden)

    S. L. Chu

    2013-03-01

    Full Text Available Continuous growth in the use of multimedia applications on portable devices makes the mobile computer systemshave an increasing complexity. The functionalities of the used SOC chips and silicon intelligent properties in theseportable devices are become complicated and hard to design. Traditional digital circuit designs adopt register transferlevel with timing control methodologies, which focus on the datapath composition, timing control of registers, and thefunctions of combinational circuits. However, the huge amount of control and synchronous signals of the abovecomponents are difficult to design and debug. The timing costs of design and verification are increased dramatically.This paper proposed a new design methodology of digital system, called data-oriented methodology, to deal with theabove problems, by using Bluespec SystemVerilog HDL and the corresponding tools. Instead of conventional timingcontrolmechanism, the data-oriented methodology adopts simple handshaking protocol, blocking transferring, andexplicitly register/FIFO declaration for communicating between adjacent modules. The designs of FDCT/IDCT andpipelined MIPS-like CPU are adopted to compare the design costs of conventional timing-control and data-orientedmethodologies. The chip performance and FPGA proven of these two designs are discussed

  14. Concept Generation for Design Creativity A Systematized Theory and Methodology

    CERN Document Server

    Taura, Toshiharu

    2013-01-01

    The concept generation process seems like an intuitional thought: difficult to capture and perform, although everyone is capable of it. It is not an analytical process but a synthetic process which has yet to be clarified. Furthermore, new research methods for investigating the concept generation process—a very difficult task since the concept generation process is driven by inner feelings deeply etched in the mind—are necessary to establish its theory and methodology.  Concept Generation for Design Creativity—A Systematized Theory and Methodology presents the concept generation process both theoretically and methodologically. Theoretically, the concept generation process is discussed by comparing metaphor, abduction, and General Design Theory from the perspective of similarities and dissimilarities. Property mapping, concept blending, and concept integration in thematic relation have been explained methodologically. So far, these theories and methods have been discussed independently, and the relation...

  15. Cost-utility analysis: Current methodological issues and future perspectives

    Directory of Open Access Journals (Sweden)

    Mark J C Nuijten

    2011-06-01

    Full Text Available The use of cost-effectiveness as final criterion in the reimbursement process for listing of new pharmaceuticals can be questioned from a scientific and policy point of view. There is a lack of consensus on main methodological issues and consequently we may question the appropriateness of the use of cost-effectiveness data in health care decision-making. Another concern is the appropriateness of the selection and use of an incremental cost-effectiveness threshold (Cost/QALY. In this review, we focus mainly on only some key methodological concerns relating to discounting, the utility concept, cost assessment and modelling methodologies. Finally we will consider the relevance of some other important decision criteria, like social values and equity.

  16. Octopus: A Design Methodology for Motion Capture Wearables

    Science.gov (United States)

    2017-01-01

    Human motion capture (MoCap) is widely recognised for its usefulness and application in different fields, such as health, sports, and leisure; therefore, its inclusion in current wearables (MoCap-wearables) is increasing, and it may be very useful in a context of intelligent objects interconnected with each other and to the cloud in the Internet of Things (IoT). However, capturing human movement adequately requires addressing difficult-to-satisfy requirements, which means that the applications that are possible with this technology are held back by a series of accessibility barriers, some technological and some regarding usability. To overcome these barriers and generate products with greater wearability that are more efficient and accessible, factors are compiled through a review of publications and market research. The result of this analysis is a design methodology called Octopus, which ranks these factors and schematises them. Octopus provides a tool that can help define design requirements for multidisciplinary teams, generating a common framework and offering a new method of communication between them. PMID:28809786

  17. [Active teaching-learning methodologies in health education: current debates].

    Science.gov (United States)

    Mitre, Sandra Minardi; Siqueira-Batista, Rodrigo; Girardi-de-Mendonça, José Márcio; de Morais-Pinto, Neila Maria; Meirelles, Cynthia de Almeida Brandão; Pinto-Porto, Cláudia; Moreira, Tânia; Hoffmann, Leandro Marcial Amaral

    2008-12-01

    The vertiginous transformations of the contemporary societies have been raising questions concerning aspects of professional education. Such questions have been raised in a more and more incisive way. This debate gains a new shape when applied to health work, where theory and practice cannot be dissociated, and where the development of an integral vision of the human being and the amplification of the concept care are essential for a proper performance. Based on these considerations, this article aims to discuss the main methodological transformations in the education process of health professionals, with emphasis to active teaching-learning methodologies.

  18. Design of Sustainable Blended Products using an Integrated Methodology

    DEFF Research Database (Denmark)

    Yunus, Nor Alafiza Binti; Gernaey, Krist; Woodley, John

    2013-01-01

    This paper presents a systematic methodology for designing blended products consisting of three stages; product design, process identification and experimental verification. The product design stage is considered in this paper. The objective of this stage is to screen and select suitable chemicals...... to be used as building blocks in the mixture design, and then to propose the blend formulations that fulfill the desired product attributes. The result is a set of blends that match the constraints, the compositions, values of the target properties and information about their miscibility. The methodology has...... been applied to design several blended products. A case study on design of blended lubricants is highlighted. The objective is to identify blended products that satisfy the product attributes with at least similar or better performance compared to conventional products....

  19. Design of Sustainable Blended Products using an Integrated Methodology

    DEFF Research Database (Denmark)

    Yunus, Nor Alafiza Binti; Gernaey, Krist; Woodley, John

    2013-01-01

    This paper presents a systematic methodology for designing blended products consisting of three stages; product design, process identification and experimental verification. The product design stage is considered in this paper. The objective of this stage is to screen and select suitable chemical...... been applied to design several blended products. A case study on design of blended lubricants is highlighted. The objective is to identify blended products that satisfy the product attributes with at least similar or better performance compared to conventional products.......This paper presents a systematic methodology for designing blended products consisting of three stages; product design, process identification and experimental verification. The product design stage is considered in this paper. The objective of this stage is to screen and select suitable chemicals...... to be used as building blocks in the mixture design, and then to propose the blend formulations that fulfill the desired product attributes. The result is a set of blends that match the constraints, the compositions, values of the target properties and information about their miscibility. The methodology has...

  20. A Structured Design for Test Methodology: A Case Study

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper is a case study of a structured Design for Test (DFT) methodology that was adopted for our ASIC project used in High-Definition TV system. The methodology includes the following features, full-scan for chip test, test point insertion, test, path delay test, embedded SRAM Build-In Self Test (BIST), and also the implementation of IEEE 1149.1 Standard. The paper discusses details of the ASIC designs and technology. Our chip has a 2+ million transistors and large embedded memory, which brought us extra test challenge.

  1. A design methodology to reduce waste in the construction process

    Institute of Scientific and Technical Information of China (English)

    AndrewN.BALDWIN; SimonA.AUSTIN; AndrewKEYS

    2003-01-01

    This paper describes a conceptual tool to enable construction professional to identify where waste is generated during the construction of buildings and address how it can be reduced. It allows an improvement in the waste management practices on site by forecasting future waste types and volumes. It will reduce waste volumes on site through identification of wasteful design practices. The tool contributes to all stages of design and construction. At the Concept Stage of Design the proposed methodology provides a framework for reducing waste through better informed decisions. At the Detailed Design Stage it gives a methodology to address the areas of concern and provide focused information to aid the reduction of waste through informed design decisions. During construction it provides a tool to predict waste types arising on site thus allowing a system of proaclive waste management that will aid skip segregation strategies leading to improved waste recycling and waste reuse.

  2. Methodology of Neural Design: Applications in Microwave Engineering

    Directory of Open Access Journals (Sweden)

    Z. Raida

    2006-06-01

    Full Text Available In the paper, an original methodology for the automatic creation of neural models of microwave structures is proposed and verified. Following the methodology, neural models of the prescribed accuracy are built within the minimum CPU time. Validity of the proposed methodology is verified by developing neural models of selected microwave structures. Functionality of neural models is verified in a design - a neural model is joined with a genetic algorithm to find a global minimum of a formulated objective function. The objective function is minimized using different versions of genetic algorithms, and their mutual combinations. The verified methodology of the automated creation of accurate neural models of microwave structures, and their association with global optimization routines are the most important original features of the paper.

  3. Quantum circuit physical design methodology with emphasis on physical synthesis

    Science.gov (United States)

    Mohammadzadeh, Naser; Saheb Zamani, Morteza; Sedighi, Mehdi

    2013-11-01

    In our previous works, we have introduced the concept of "physical synthesis" as a method to consider the mutual effects of quantum circuit synthesis and physical design. While physical synthesis can involve various techniques to improve the characteristics of the resulting quantum circuit, we have proposed two techniques (namely gate exchanging and auxiliary qubit selection) to demonstrate the effectiveness of the physical synthesis. However, the previous contributions focused mainly on the physical synthesis concept, and the techniques were proposed only as a proof of concept. In this paper, we propose a methodological framework for physical synthesis that involves all previously proposed techniques along with a newly introduced one (called auxiliary qubit insertion). We will show that the entire flow can be seen as one monolithic methodology. The proposed methodology is analyzed using a large set of benchmarks. Experimental results show that the proposed methodology decreases the average latency of quantum circuits by about 36.81 % for the attempted benchmarks.

  4. Methodology for a stormwater sensitive urban watershed design

    Science.gov (United States)

    Romnée, Ambroise; Evrard, Arnaud; Trachte, Sophie

    2015-11-01

    In urban stormwater management, decentralized systems are nowadays worldwide experimented, including stormwater best management practices. However, a watershed-scale approach, relevant for urban hydrology, is almost always neglected when designing a stormwater management plan with best management practices. As a consequence, urban designers fail to convince public authorities of the actual hydrologic effectiveness of such an approach to urban watershed stormwater management. In this paper, we develop a design oriented methodology for studying the morphology of an urban watershed in terms of sustainable stormwater management. The methodology is a five-step method, firstly based on the cartographic analysis of many stormwater relevant indicators regarding the landscape, the urban fabric and the governance. The second step focuses on the identification of many territorial stakes and their corresponding strategies of a decentralized stormwater management. Based on the indicators, the stakes and the strategies, the third step defines many spatial typologies regarding the roadway system and the urban fabric system. The fourth step determines many stormwater management scenarios to be applied to both spatial typologies systems. The fifth step is the design of decentralized stormwater management projects integrating BMPs into each spatial typology. The methodology aims to advise urban designers and engineering offices in the right location and selection of BMPs without given them a hypothetical unique solution. Since every location and every watershed is different due to local guidelines and stakeholders, this paper provide a methodology for a stormwater sensitive urban watershed design that could be reproduced everywhere. As an example, the methodology is applied as a case study to an urban watershed in Belgium, confirming that the method is applicable to any urban watershed. This paper should be helpful for engineering and design offices in urban hydrology to define a

  5. Design Methodology for Self-organized Mobile Networks Based

    Directory of Open Access Journals (Sweden)

    John Petearson Anzola

    2016-06-01

    Full Text Available The methodology proposed in this article enables a systematic design of routing algorithms based on schemes of biclustering, which allows you to respond with timely techniques, clustering heuristics proposed by a researcher, and a focused approach to routing in the choice of clusterhead nodes. This process uses heuristics aimed at improving the different costs in communication surface groups called biclusters. This methodology globally enables a variety of techniques and heuristics of clustering that have been addressed in routing algorithms, but we have not explored all possible alternatives and their different assessments. Therefore, the methodology oriented design research of routing algorithms based on biclustering schemes will allow new concepts of evolutionary routing along with the ability to adapt the topological changes that occur in self-organized data networks.

  6. Aerodynamic Design Methodology for Blended Wing Body Transport

    Institute of Scientific and Technical Information of China (English)

    LI Peifeng; ZHANG Binqian; CHEN Yingchun; YUAN Changsheng; LIN Yu

    2012-01-01

    This paper puts forward a design idea for blended wing body (BWB).The idea is described as that cruise point,maximum lift to drag point and pitch trim point are in the same flight attitude.According to this design idea,design objectives and constraints are defined.By applying low and high fidelity aerodynamic analysis tools,BWB aerodynamic design methodology is established by the combination of optimization design and inverse design methods.High lift to drag ratio,pitch trim and acceptable buffet margin can be achieved by this design methodology.For 300-passenger BWB configuration based on static stability design,as compared with initial configuration,the maximum lift to drag ratio and pitch trim are achieved at cruise condition,zero lift pitching moment is positive,and buffet characteristics is well.Fuel burn of 300-passenger BWB configuration is also significantly reduced as compared with conventional civil transports.Because aerodynamic design is carried out under the constraints of BWB design requirements,the design configuration fulfills the demands for interior layout and provides a solid foundation for continuous work.

  7. Dictionary Quality and Dictionary Design: A Methodology for ...

    African Journals Online (AJOL)

    rbr

    how this methodology can be used to design functional dictionaries and to assess the functional quality of the ... sos, for the innovative way in which the problems of learners have been approached by redesigning various aspects of the content, structure, style, etc. ..... under the concept of the functional quality of a dictionary.

  8. Viability, Advantages and Design Methodologies of M-Learning Delivery

    Science.gov (United States)

    Zabel, Todd W.

    2010-01-01

    The purpose of this study was to examine the viability and principle design methodologies of Mobile Learning models in developing regions. Demographic and market studies were utilized to determine the viability of M-Learning delivery as well as best uses for such technologies and methods given socioeconomic and political conditions within the…

  9. Current methodology and methods in psychophysiological studies of creative thinking.

    Science.gov (United States)

    Bechtereva, N P; Danko, S G; Medvedev, S V

    2007-05-01

    Important points on methodology and detailed description of methods used in polymodal psychophysiological studies of human verbal creative thinking are presented. The psychophysiological studies were conducted with healthy volunteers during implementations of specially developed and adapted psychological tests aimed to bring the subjects into states of verbal creative thinking. Four different task sets ("story composition", "associative chains", "original definitions", "proverb sense flipping") were developed and applied. Positron emission tomography of regional cerebral blood flow (rCBF) and state-related quantitative electroencephalography (power and coherence evaluated) were used. The effectiveness of the methods is illustrated with figures.

  10. Beyond Dualisms in Methodology: An Integrative Design Research Medium "MAPS" and some Reflections

    OpenAIRE

    Chow, Rosan; Jonas, Wolfgang

    2009-01-01

    Design research is an academic issue and increasingly an essential success factor for industrial, organizational and social innovation. The fierce rejection of 1st generation design methods in the early 1970s resulted in the postmodernist attitude of "no methods", and subsequently, after more than a decade, in the strong adoption of scientific methods, or "the" scientific method, for design research. The current situation regarding methodology is characterized by unproductive dualisms such as...

  11. Biomimetics as a design methodology – possibilities and challenges

    DEFF Research Database (Denmark)

    Lenau, Torben Anker

    2009-01-01

    Biomimetics – or bionik as it is called in parts of Europe – offer a number of promising opportunities and challenges for the designer. The paper investigates how biomimetics as a design methodology is used in engineering design by looking at examples of biological searches and highlight...... the possibilities and challenges. Biomimetics for engineering design is explored through an experiment involving 12 design engineering students. For 7 selected problem areas they searched biology literature available at a university library and identified a number of biological solutions. Central solution...... principles were formulated and used for designing technical items that could be used to solve the initial problems. Experiences are that biomimetic design can be made successfully using commonly available biological literature and internet resources and that designers without detailed biological knowledge...

  12. Conceptual design and optimization methodology for box wing aircraft

    OpenAIRE

    Jemitola, Paul Olugbeji

    2012-01-01

    A conceptual design optimization methodology was developed for a medium range box wing aircraft. A baseline conventional cantilever wing aircraft designed for the same mis- sion and payload was also optimized alongside a baseline box wing aircraft. An empirical formula for the mass estimation of the fore and aft wings of the box wing aircraft was derived by relating conventional cantilever wings to box wing aircraft wings. The results indicate that the fore and aft wings would ...

  13. FOREWORD: Computational methodologies for designing materials Computational methodologies for designing materials

    Science.gov (United States)

    Rahman, Talat S.

    2009-02-01

    It would be fair to say that in the past few decades, theory and computer modeling have played a major role in elucidating the microscopic factors that dictate the properties of functional novel materials. Together with advances in experimental techniques, theoretical methods are becoming increasingly capable of predicting properties of materials at different length scales, thereby bringing in sight the long-sought goal of designing material properties according to need. Advances in computer technology and their availability at a reasonable cost around the world have made tit all the more urgent to disseminate what is now known about these modern computational techniques. In this special issue on computational methodologies for materials by design we have tried to solicit articles from authors whose works collectively represent the microcosm of developments in the area. This turned out to be a difficult task for a variety of reasons, not the least of which is space limitation in this special issue. Nevertheless, we gathered twenty articles that represent some of the important directions in which theory and modeling are proceeding in the general effort to capture the ability to produce materials by design. The majority of papers presented here focus on technique developments that are expected to uncover further the fundamental processes responsible for material properties, and for their growth modes and morphological evolutions. As for material properties, some of the articles here address the challenges that continue to emerge from attempts at accurate descriptions of magnetic properties, of electronically excited states, and of sparse matter, all of which demand new looks at density functional theory (DFT). I should hasten to add that much of the success in accurate computational modeling of materials emanates from the remarkable predictive power of DFT, without which we would not be able to place the subject on firm theoretical grounds. As we know and will also

  14. Failure detection system design methodology. Ph.D. Thesis

    Science.gov (United States)

    Chow, E. Y.

    1980-01-01

    The design of a failure detection and identification system consists of designing a robust residual generation process and a high performance decision making process. The design of these two processes are examined separately. Residual generation is based on analytical redundancy. Redundancy relations that are insensitive to modelling errors and noise effects are important for designing robust residual generation processes. The characterization of the concept of analytical redundancy in terms of a generalized parity space provides a framework in which a systematic approach to the determination of robust redundancy relations are developed. The Bayesian approach is adopted for the design of high performance decision processes. The FDI decision problem is formulated as a Bayes sequential decision problem. Since the optimal decision rule is incomputable, a methodology for designing suboptimal rules is proposed. A numerical algorithm is developed to facilitate the design and performance evaluation of suboptimal rules.

  15. Program Calculates Current Densities Of Electronic Designs

    Science.gov (United States)

    Cox, Brian

    1996-01-01

    PDENSITY computer program calculates current densities for use in calculating power densities of electronic designs. Reads parts-list file for given design, file containing current required for each part, and file containing size of each part. For each part in design, program calculates current density in units of milliamperes per square inch. Written by use of AWK utility for Sun4-series computers running SunOS 4.x and IBM PC-series and compatible computers running MS-DOS. Sun version of program (NPO-19588). PC version of program (NPO-19171).

  16. Computer aided die design: A new open-source methodology

    Science.gov (United States)

    Carneiro, Olga Sousa; Rajkumar, Ananth; Ferrás, Luís Lima; Fernandes, Célio; Sacramento, Alberto; Nóbrega, João Miguel

    2017-05-01

    In this work we present a detailed description of how to use open source based computer codes to aid the design of complex profile extrusion dies, aiming to improve its flow distribution. The work encompasses the description of the overall open-source die design methodology, the implementation of the energy conservation equation in an existing OpenFOAM® solver, which will be then capable of simulating the steady non-isothermal flow of an incompressible generalized Newtonian fluid, and two case studies to illustrate the capabilities and practical usefulness of the developed methodology. The results obtained with these case studies, used to solve real industrial problems, demonstrate that the computational design aid is an excellent alternative, from economical and technical points of view, to the experimental trial-and-error procedure commonly used in industry.

  17. An Adaptive Design Methodology for Reduction of Product Development Risk

    CERN Document Server

    Pakala, Hara Gopal Mani; Kvsvn, Dr Raju; Khan, Dr Ibrahim; 10.5121/ijasuc.2011.2303

    2011-01-01

    Embedded systems interaction with environment inherently complicates understanding of requirements and their correct implementation. However, product uncertainty is highest during early stages of development. Design verification is an essential step in the development of any system, especially for Embedded System. This paper introduces a novel adaptive design methodology, which incorporates step-wise prototyping and verification. With each adaptive step product-realization level is enhanced while decreasing the level of product uncertainty, thereby reducing the overall costs. The back-bone of this frame-work is the development of Domain Specific Operational (DOP) Model and the associated Verification Instrumentation for Test and Evaluation, developed based on the DOP model. Together they generate functionally valid test-sequence for carrying out prototype evaluation. With the help of a case study 'Multimode Detection Subsystem' the application of this method is sketched. The design methodologies can be compar...

  18. Integration of process design and controller design for chemical processes using model-based methodology

    DEFF Research Database (Denmark)

    Abd.Hamid, Mohd-Kamaruddin; Sin, Gürkan; Gani, Rafiqul

    2010-01-01

    In this paper, a novel systematic model-based methodology for performing integrated process design and controller design (IPDC) for chemical processes is presented. The methodology uses a decomposition method to solve the IPDC typically formulated as a mathematical programming (optimization...... with constraints) problem. Accordingly the optimization problem is decomposed into four sub-problems: (i) pre-analysis, (ii) design analysis, (iii) controller design analysis, and (iv) final selection and verification, which are relatively easier to solve. The methodology makes use of thermodynamic-process...... insights and the reverse design approach to arrive at the final process design–controller design decisions. The developed methodology is illustrated through the design of: (a) a single reactor, (b) a single separator, and (c) a reactor–separator-recycle system and shown to provide effective solutions...

  19. A bioclimatic design methodology for urban outdoor spaces

    Science.gov (United States)

    Swaid, H.; Bar-El, M.; Hoffman, M. E.

    1993-03-01

    The development of a bioclimatic urban design methodology is described. The cluster thermal time constant ( CTTC) model for predicting street-level urban air temperature variations is coupled with the wind-profile power law and the index of thermal stress (ITS.) for human comfort. The CTTC model and the power law produce the diurnal air temperature and wind speed variations in various canyonlike urban forms. The thermal comfort requirements for lightly-dressed, moderately-walking/seated persons in the outdoor space in summer are then obtained using the ITS. model. The proposed methodology enables a first-order assessment of the climatic implications of different features of the physical structure of the city such as street orientation, canyon height-to-width ratio, building density, and street shading. The application of the proposed methodology is demonstrated for Tel Aviv.

  20. Extending Design Science Research Methodology for a Multicultural World

    Science.gov (United States)

    Lawrence, Carl; Tuunanen, Tuure; Myers, Michael D.

    Design science research (DSR) is a relatively new approach in information systems research. A fundamental tenet of DSR is that understanding comes from creating information technology artifacts. However, with an increasingly connected and globalized world, designing IT artifacts for a multicultural world is a challenge. The purpose of this paper, therefore, is to propose extending the DSR methodology by integrating critical ethnography to the evaluation phase. Critical ethnography provides a way for IS researchers using DSR to better understand culture, and may help to ensure that IT artifacts are designed for a variety of cultural contexts.

  1. Towards the evaluation of current wind farm assessment methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Dorval, J.; Masson, C. [Ecole de Technologie Superieure, Montreal, PQ (Canada); Gagnon, Y. [Moncton Univ., NB (Canada). Dept. of Wind Engineering

    2010-07-01

    Canada's wind energy industry is experiencing significant growth. Government initiatives such as the wind power production incentive program (WPPI) may result in a cumulative installed wind energy capacity of up to 10,000 MW by 2015. However, the methods used to assess wind farm performance have never been thoroughly investigated in a specifically Canadian context. This project was conducted to provide a more accurate understanding of the limitations of various wind farm performance measuring methods and recommend effective methodologies based on the effect of terrain, the position of the wind turbines, and wind characteristics. The study was conducted at 5 wind farms in various Canadian locations, including Prince Edward Island (PEI). A full year of data for each wind farm was used to determine wind speed, wind direction, temperature, pressure, relative humidity, power, and Nacelle orientation. Various wind resource assessment software programs were analyzed in order to evaluate topography and roughness effects, wake analyses, and to compare results from the models with actual wind speed data. tabs., figs.

  2. Efficient preliminary floating offshore wind turbine design and testing methodologies and application to a concrete spar design.

    Science.gov (United States)

    Matha, Denis; Sandner, Frank; Molins, Climent; Campos, Alexis; Cheng, Po Wen

    2015-02-28

    The current key challenge in the floating offshore wind turbine industry and research is on designing economic floating systems that can compete with fixed-bottom offshore turbines in terms of levelized cost of energy. The preliminary platform design, as well as early experimental design assessments, are critical elements in the overall design process. In this contribution, a brief review of current floating offshore wind turbine platform pre-design and scaled testing methodologies is provided, with a focus on their ability to accommodate the coupled dynamic behaviour of floating offshore wind systems. The exemplary design and testing methodology for a monolithic concrete spar platform as performed within the European KIC AFOSP project is presented. Results from the experimental tests compared to numerical simulations are presented and analysed and show very good agreement for relevant basic dynamic platform properties. Extreme and fatigue loads and cost analysis of the AFOSP system confirm the viability of the presented design process. In summary, the exemplary application of the reduced design and testing methodology for AFOSP confirms that it represents a viable procedure during pre-design of floating offshore wind turbine platforms.

  3. ProSAR: a new methodology for combinatorial library design.

    Science.gov (United States)

    Chen, Hongming; Börjesson, Ulf; Engkvist, Ola; Kogej, Thierry; Svensson, Mats A; Blomberg, Niklas; Weigelt, Dirk; Burrows, Jeremy N; Lange, Tim

    2009-03-01

    A method is introduced for performing reagent selection for chemical library design based on topological (2D) pharmacophore fingerprints. Optimal reagent selection is achieved by optimizing the Shannon entropy of the 2D pharmacophore distribution for the reagent set. The method, termed ProSAR, is therefore expected to enumerate compounds that could serve as a good starting point for deriving a structure activity relationship (SAR) in combinatorial library design. This methodology is exemplified by library design examples where the active compounds were already known. The results show that most of the pharmacophores on the substituents for the active compounds are covered by the designed library. This strategy is further expanded to include product property profiles for aqueous solubility, hERG risk assessment, etc. in the optimization process so that the reagent pharmacophore diversity and the product property profile are optimized simultaneously via a genetic algorithm. This strategy is applied to a two-dimensional library design example and compared with libraries designed by a diversity based strategy which minimizes the average ensemble Tanimoto similarity. Our results show that by using the PSAR methodology, libraries can be designed with simultaneously good pharmacophore coverage and product property profile.

  4. Cyber-Informed Engineering: The Need for a New Risk Informed and Design Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Price, Joseph Daniel [Idaho National Laboratory; Anderson, Robert Stephen [Idaho National Laboratory

    2015-06-01

    Current engineering and risk management methodologies do not contain the foundational assumptions required to address the intelligent adversary’s capabilities in malevolent cyber attacks. Current methodologies focus on equipment failures or human error as initiating events for a hazard, while cyber attacks use the functionality of a trusted system to perform operations outside of the intended design and without the operator’s knowledge. These threats can by-pass or manipulate traditionally engineered safety barriers and present false information, invalidating the fundamental basis of a safety analysis. Cyber threats must be fundamentally analyzed from a completely new perspective where neither equipment nor human operation can be fully trusted. A new risk analysis and design methodology needs to be developed to address this rapidly evolving threatscape.

  5. Respondent-Driven Sampling: An Assessment of Current Methodology*

    OpenAIRE

    Gile, Krista J.; Handcock, Mark S.

    2010-01-01

    Respondent-Driven Sampling (RDS) employs a variant of a link-tracing network sampling strategy to collect data from hard-to-reach populations. By tracing the links in the underlying social network, the process exploits the social structure to expand the sample and reduce its dependence on the initial (convenience) sample. The primary goal of RDS is typically to estimate population averages in the hard-to-reach population. The current estimates make strong assumptions in order to treat the dat...

  6. QUALITY IMPROVEMENT IN MULTIRESPONSE EXPERIMENTS THROUGH ROBUST DESIGN METHODOLOGY

    Directory of Open Access Journals (Sweden)

    M. Shilpa

    2012-06-01

    Full Text Available Robust design methodology aims at reducing the variability in the product performance in the presence of noise factors. Experiments involving simultaneous optimization of more than one quality characteristic are known as multiresponse experiments which are used in the development and improvement of industrial processes and products. In this paper, robust design methodology is applied to optimize the process parameters during a particular operation of rotary driving shaft manufacturing process. The three important quality characteristics of the shaft considered here are of type Nominal-the-best, Smaller-the-better and Fraction defective. Simultaneous optimization of these responses is carried out by identifying the control parameters and conducting the experimentation using L9 orthogonal array.

  7. An automated methodology development. [software design for combat simulation

    Science.gov (United States)

    Hawley, L. R.

    1985-01-01

    The design methodology employed in testing the applicability of Ada in large-scale combat simulations is described. Ada was considered as a substitute for FORTRAN to lower life cycle costs and ease the program development efforts. An object-oriented approach was taken, which featured definitions of military targets, the capability of manipulating their condition in real-time, and one-to-one correlation between the object states and real world states. The simulation design process was automated by the problem statement language (PSL)/problem statement analyzer (PSA). The PSL/PSA system accessed the problem data base directly to enhance the code efficiency by, e.g., eliminating non-used subroutines, and provided for automated report generation, besides allowing for functional and interface descriptions. The ways in which the methodology satisfied the responsiveness, reliability, transportability, modifiability, timeliness and efficiency goals are discussed.

  8. Formulation of a methodology for power circuit design optimization

    Science.gov (United States)

    Yu, Y.; Bachmann, M.; Lee, F. C. Y.; Triner, J. E.

    1976-01-01

    A methodology for optimizing power-processor designs is described which achieves optimization with respect to some power-processor characteristic deemed particularly desirable by the designer, such as weight or efficiency. Optimization theory based on Lagrange multipliers is reviewed together with nonlinear programming techniques employing penalty functions. The methodology, the task of which is to minimize an objective function subject to design constraints, is demonstrated with the aid of four examples: optimum-weight core selection for an inductor with a predetermined winding size, optimum-weight inductor design with a given loss constraint, optimum-loss inductor design with a given weight constraint, and a comparison of optimum-weight single- and two-stage input-filter designs with identical loss and other requirement constraints. Closed-form solutions for the first three examples are obtained by applying the Lagrange-multiplier method, but solutions for the last example are found numerically through the use of the sequential unconstrained minimization technique.

  9. Learning design: reflections upon the current landscape

    Directory of Open Access Journals (Sweden)

    Brock Craft

    2012-08-01

    Full Text Available The mounting wealth of open and readily available information and the accelerated evolution of social, mobile and creative technologies call for a re-conceptualisation of the role of educators: from providers of knowledge to designers of learning. This call is reverberated by the rising trend of research in learning design (LD. Addressing this, the Art and Science of Learning Design workshop brought together leading voices in the field, and provided a forum for discussing its key issues. It focused on three major themes: (1 practices, methods and methodologies, (2 tools and resources and (3 theoretical frameworks. This paper proposes a definition of LD, reviews the main contributions from the workshop, and suggests some challenges for future research.

  10. Thin Film Heat Flux Sensors: Design and Methodology

    Science.gov (United States)

    Fralick, Gustave C.; Wrbanek, John D.

    2013-01-01

    Thin Film Heat Flux Sensors: Design and Methodology: (1) Heat flux is one of a number of parameters, together with pressure, temperature, flow, etc. of interest to engine designers and fluid dynamists, (2) The measurement of heat flux is of interest in directly determining the cooling requirements of hot section blades and vanes, and (3)In addition, if the surface and gas temperatures are known, the measurement of heat flux provides a value for the convective heat transfer coefficient that can be compared with the value provided by CFD codes.

  11. Synergistic effects of Chinese herbal medicine: a comprehensive review of methodology and current research

    Directory of Open Access Journals (Sweden)

    Xian Zhou

    2016-07-01

    Full Text Available Traditional Chinese medicine is an important part of primary health care in Asian countries that has utilised complex herbal formulations (consisting 2 or more medicinal herbs for treating diseases over thousands of years. There seems to be a general assumption that the synergistic therapeutic effects of Chinese herbal medicine derive from the complex interactions between the multiple bioactive components within the herbs and/or herbal formulations. However, evidence to support these synergistic effects remains weak and controversial due to several reasons, including the very complex nature of Chinese herbal medicine, misconceptions about synergy, methodological challenges to study design. In this review, we clarify the definition of synergy, identify common errors in synergy research and describe current methodological approaches to test for synergistic interaction. We discuss the strengthen and weakness of these models in the context of Chinese herbal medicine and summarise the current status of synergy research in CHM. Despite the availability of some scientific data to support the synergistic effects of multi-herbal and/or herb-drug combinations, the level of evidence remains low and the clinical relevancy of most of these findings is undetermined. There remain significant challenges in the development of suitable methods for synergistic studies of complex herbal combinations.

  12. When Playing Meets Learning: Methodological Framework for Designing Educational Games

    Science.gov (United States)

    Linek, Stephanie B.; Schwarz, Daniel; Bopp, Matthias; Albert, Dietrich

    Game-based learning builds upon the idea of using the motivational potential of video games in the educational context. Thus, the design of educational games has to address optimizing enjoyment as well as optimizing learning. Within the EC-project ELEKTRA a methodological framework for the conceptual design of educational games was developed. Thereby state-of-the-art psycho-pedagogical approaches were combined with insights of media-psychology as well as with best-practice game design. This science-based interdisciplinary approach was enriched by enclosed empirical research to answer open questions on educational game-design. Additionally, several evaluation-cycles were implemented to achieve further improvements. The psycho-pedagogical core of the methodology can be summarized by the ELEKTRA's 4Ms: Macroadaptivity, Microadaptivity, Metacognition, and Motivation. The conceptual framework is structured in eight phases which have several interconnections and feedback-cycles that enable a close interdisciplinary collaboration between game design, pedagogy, cognitive science and media psychology.

  13. Acceptance testing for PACS: from methodology to design to implementation

    Science.gov (United States)

    Liu, Brent J.; Huang, H. K.

    2004-04-01

    Acceptance Testing (AT) is a crucial step in the implementation process of a PACS within a clinical environment. AT determines whether the PACS is ready for clinical use and marks the official sign off of the PACS product. Most PACS vendors have Acceptance Testing (AT) plans, however, these plans do not provide a complete and robust evaluation of the full system. In addition, different sites will have different special requirements that vendor AT plans do not cover. The purpose of this paper is to introduce a protocol for AT design and present case studies of AT performed on clinical PACS. A methodology is presented that includes identifying testing components within PACS, quality assurance for both functionality and performance, and technical testing focusing on key single points-of-failure within the PACS product. Tools and resources that provide assistance in performing AT are discussed. In addition, implementation of the AT within the clinical environment and the overall implementation timeline of the PACS process are presented. Finally, case studies of actual AT of clinical PACS performed in the healthcare environment will be reviewed. The methodology for designing and implementing a robust AT plan for PACS was documented and has been used in PACS acceptance tests in several sites. This methodology can be applied to any PACS and can be used as a validation for the PACS product being acquired by radiology departments and hospitals. A methodology for AT design and implementation was presented that can be applied to future PACS installations. A robust AT plan for a PACS installation can increase both the utilization and satisfaction of a successful implementation of a PACS product that benefits both vendor and customer.

  14. Metabolomics: current state and evolving methodologies and tools.

    Science.gov (United States)

    Oldiges, Marco; Lütz, Stephan; Pflug, Simon; Schroer, Kirsten; Stein, Nadine; Wiendahl, Christiane

    2007-09-01

    In recent years, metabolomics developed to an accepted and valuable tool in life sciences. Substantial improvements of analytical hardware allow metabolomics to run routinely now. Data are successfully used to investigate genotype-phenotype relations of strains and mutants. Metabolomics facilitates metabolic engineering to optimise mircoorganisms for white biotechnology and spreads to the investigation of biotransformations and cell culture. Metabolomics serves not only as a source of qualitative but also quantitative data of intra-cellular metabolites essential for the model-based description of the metabolic network operating under in vivo conditions. To collect reliable metabolome data sets, culture and sampling conditions, as well as the cells' metabolic state, are crucial. Hence, application of biochemical engineering principles and method standardisation efforts become important. Together with the other more established omics technologies, metabolomics will strengthen its claim to contribute to the detailed understanding of the in vivo function of gene products, biochemical and regulatory networks and, even more ambitious, the mathematical description and simulation of the whole cell in the systems biology approach. This knowledge will allow the construction of designer organisms for process application using biotransformation and fermentative approaches making effective use of single enzymes, whole microbial and even higher cells.

  15. Space station definitions, design, and development. Task 5: Multiple arm telerobot coordination and control: Manipulator design methodology

    Science.gov (United States)

    Stoughton, R. M.

    1990-01-01

    A proposed methodology applicable to the design of manipulator systems is described. The current design process is especially weak in the preliminary design phase, since there is no accepted measure to be used in trading off different options available for the various subsystems. The design process described uses Cartesian End-Effector Impedance as a measure of performance for the system. Having this measure of performance, it is shown how it may be used to determine the trade-offs necessary to the preliminary design phase. The design process involves three main parts: (1) determination of desired system performance in terms of End-Effector Impedance; (2) trade-off design options to achieve this desired performance; and (3) verification of system performance through laboratory testing. The design process is developed using numerous examples and experiments to demonstrate the feasability of this approach to manipulator design.

  16. Fuel cell cathode air filters: Methodologies for design and optimization

    Science.gov (United States)

    Kennedy, Daniel M.; Cahela, Donald R.; Zhu, Wenhua H.; Westrom, Kenneth C.; Nelms, R. Mark; Tatarchuk, Bruce J.

    Proton exchange membrane (PEM) fuel cells experience performance degradation, such as reduction in efficiency and life, as a result of poisoning of platinum catalysts by airborne contaminants. Research on these contaminant effects suggests that the best possible solution to allowing fuel cells to operate in contaminated environments is by filtration of the harmful contaminants from the cathode air. A cathode air filter design methodology was created that connects properties of cathode air stream, filter design options, and filter footprint, to a set of adsorptive filter parameters that must be optimized to efficiently operate the fuel cell. Filter optimization requires a study of the trade off between two causal factors of power loss: first, a reduction in power production due to poisoning of the platinum catalyst by chemical contaminants and second, an increase in power requirements to operate the air compressor with a larger pressure drop from additional contaminant filtration. The design methodology was successfully applied to a 1.2 kW fuel cell using a programmable algorithm and predictions were made about the relationships between inlet concentration, breakthrough time, filter design, pressure drop, and compressor power requirements.

  17. Engineering Design Optimization Based on Intelligent Response Surface Methodology

    Institute of Scientific and Technical Information of China (English)

    SONG Guo-hui; WU Yu; LI Cong-xin

    2008-01-01

    An intelligent response surface methodology (IRSM) was proposed to achieve the most competitivemetal forming products, in which artificial intelligence technologies are introduced into the optimization process.It is used as simple and inexpensive replacement for computationally expensive simulation model. In IRSM,the optimal design space can be reduced greatly without any prior information about function distribution.Also, by identifying the approximation error region, new design points can be supplemented correspondingly toimprove the response surface model effectively. The procedure is iterated until the accuracy reaches the desiredthreshold value. Thus, the global optimization can be performed based on this substitute model. Finally, wepresent an optimization design example about roll forming of a "U" channel product.

  18. Design principles for shift current photovoltaics.

    Science.gov (United States)

    Cook, Ashley M; M Fregoso, Benjamin; de Juan, Fernando; Coh, Sinisa; Moore, Joel E

    2017-01-25

    While the basic principles of conventional solar cells are well understood, little attention has gone towards maximizing the efficiency of photovoltaic devices based on shift currents. By analysing effective models, here we outline simple design principles for the optimization of shift currents for frequencies near the band gap. Our method allows us to express the band edge shift current in terms of a few model parameters and to show it depends explicitly on wavefunctions in addition to standard band structure. We use our approach to identify two classes of shift current photovoltaics, ferroelectric polymer films and single-layer orthorhombic monochalcogenides such as GeS, which display the largest band edge responsivities reported so far. Moreover, exploring the parameter space of the tight-binding models that describe them we find photoresponsivities that can exceed 100 mA W(-1). Our results illustrate the great potential of shift current photovoltaics to compete with conventional solar cells.

  19. Design principles for shift current photovoltaics

    Science.gov (United States)

    Cook, Ashley M.; M. Fregoso, Benjamin; de Juan, Fernando; Coh, Sinisa; Moore, Joel E.

    2017-01-01

    While the basic principles of conventional solar cells are well understood, little attention has gone towards maximizing the efficiency of photovoltaic devices based on shift currents. By analysing effective models, here we outline simple design principles for the optimization of shift currents for frequencies near the band gap. Our method allows us to express the band edge shift current in terms of a few model parameters and to show it depends explicitly on wavefunctions in addition to standard band structure. We use our approach to identify two classes of shift current photovoltaics, ferroelectric polymer films and single-layer orthorhombic monochalcogenides such as GeS, which display the largest band edge responsivities reported so far. Moreover, exploring the parameter space of the tight-binding models that describe them we find photoresponsivities that can exceed 100 mA W-1. Our results illustrate the great potential of shift current photovoltaics to compete with conventional solar cells.

  20. Experimental design methodology: the scientific tool for performance evaluation

    Science.gov (United States)

    Sadjadi, Firooz A.

    1990-09-01

    With the rapid growth of the signal and image processing technology in the last several decades has arisen the need for means of evaluating and comparing the numerous algorithms and systems that are created or are being developed. Performance evaluation, in the past, has been mostly ad hoc and incohesive. In this paper we present a systematic step by step approach for the scientific evaluation of signal and image processing algorithms and systems. This approach is based on the methodology of Experimental Design. We illustrate this method by means of an example from the field of automatic object recognition.

  1. Application of concept selection methodology in IC process design

    Science.gov (United States)

    Kim, Myung-Kul

    1993-01-01

    Search for an effective methodology practical in IC manufacturing process development led to trial of quantitative 'concept selection' methodology in selecting the 'best' alternative for interlevel dielectric (ILD) processes. A cross-functional team selected multi-criteria with scoring guidelines to be used in the definition of the 'best'. The project was targeted for the 3 level metal backend process for sub-micron gate array product. The outcome of the project showed that the maturity of the alternatives has strong influence on the scores, because scores on the adopted criteria such as yield, reliability and maturity will depend on the maturity of a particular process. At the same time, the project took longer than expected since it required data for the multiple criteria. These observations suggest that adopting a simpler procedure that can analyze total inherent controllability of a process would be more effective. The methodology of the DFS (design for simplicity) tools used in analyzing the manufacturability of such electronics products as computers, phones and other consumer electronics products could be used as an 'analogy' in constructing an evaluation method for IC processes that produce devices used in those electronics products. This could be done by focusing on the basic process operation elements rather than the layers that are being built.

  2. The mechanical design of a transfemoral prosthesis using computational tools and design methodology

    Directory of Open Access Journals (Sweden)

    John Sánchez Otero

    2012-12-01

    Full Text Available Artificial limb replacement with lower limb prostheses has been widely reported in current scientific literature. There are many lower limb prosthetic designs ranging from a single-axis knee mechanism to complex mechanisms involving microcontrollers, made from many materials ranging from lightweight, high specific strength ones (e.g., carbon fibre to traditional forms (e.g., stainless steel. However, the challenge is to design prostheses whose movement resembles the human body’s natural movement as closely as possible. Advances in prosthetics have enabled many amputees to return to their everyday activities; however, such prostheses are expensive, some costing as much as $60,000. Many of the affected population in Colombia have scarce economic resources; there is therefore a need to develop affordable functional prostheses.The Universidad del Norte’s Materials, Processes and Design Research Group and the Robotics and Intelligent Systems Group have been working on this line of research to develop modular prostheses which can be adjusted to each patient’s requirements. This research represents an initial methodological approach to developing a prosthesis in which software tools have been used (the finite element method with a criteria relationship matrix for selecting the best alternative while considering different aspects such as mod-ularity, cost, stiffness and weight.

  3. Adaptive design clinical trials: Methodology, challenges and prospect

    Directory of Open Access Journals (Sweden)

    Mahajan Rajiv

    2010-01-01

    Full Text Available New drug development is a time-consuming and expensive process. Recently, there has been stagnation in the development of novel compounds. Moreover, the attrition rate in clinical research is also on the rise. Fearing more stagnation, the Food and Drug Administration released the critical path initiative in 2004 and critical path opportunity list in 2006 thus highlighting the need of advancing innovative trial designs. One of the innovations suggested was the adaptive designed clinical trials, a method promoting introduction of pre-specified modifications in the design or statistical procedures of an on-going trial depending on the data generated from the concerned trial thus making a trial more flexible. The adaptive design trials are proposed to boost clinical research by cutting on the cost and time factor. Although the concept of adaptive designed clinical trials is round-the-corner for the last 40 years, there is still lack of uniformity and understanding on this issue. This review highlights important adaptive designed methodologies besides covering the regulatory positions on this issue.

  4. Methodologies and study designs relevant to medical education research.

    Science.gov (United States)

    Turner, Teri L; Balmer, Dorene F; Coverdale, John H

    2013-06-01

    Research is an important part of educational scholarship. Knowledge of research methodologies is essential for both conducting research as well as determining the soundness of the findings from published studies. Our goals for this paper therefore are to inform medical education researchers of the range and key components of educational research designs. We will discuss both qualitative and quantitative approaches to educational research. Qualitative methods will be presented according to traditions that have a distinguished history in particular disciplines. Quantitative methods will be presented according to an evidence-based hierarchy akin to that of evidence-based medicine with the stronger designs (systematic reviews and well conducted educational randomized controlled trials) at the top, and weaker designs (descriptive studies without comparison groups, or single case studies) at the bottom. It should be appreciated, however, that the research question determines the study design. Therefore, the onus is on the researcher to choose a design that is appropriate to answering the question. We conclude with an overview of how educational researchers should describe the study design and methods in order to provide transparency and clarity.

  5. Designing trials for pressure ulcer risk assessment research: methodological challenges.

    Science.gov (United States)

    Balzer, K; Köpke, S; Lühmann, D; Haastert, B; Kottner, J; Meyer, G

    2013-08-01

    For decades various pressure ulcer risk assessment scales (PURAS) have been developed and implemented into nursing practice despite uncertainty whether use of these tools helps to prevent pressure ulcers. According to current methodological standards, randomised controlled trials (RCTs) are required to conclusively determine the clinical efficacy and safety of this risk assessment strategy. In these trials, PURAS-aided risk assessment has to be compared to nurses' clinical judgment alone in terms of its impact on pressure ulcer incidence and adverse outcomes. However, RCTs evaluating diagnostic procedures are prone to specific risks of bias and threats to the statistical power which may challenge their validity and feasibility. This discussion paper critically reflects on the rigour and feasibility of experimental research needed to substantiate the clinical efficacy of PURAS-aided risk assessment. Based on reflections of the methodological literature, a critical appraisal of available trials on this subject and an analysis of a protocol developed for a methodologically robust cluster-RCT, this paper arrives at the following conclusions: First, available trials do not provide reliable estimates of the impact of PURAS-aided risk assessment on pressure ulcer incidence compared to nurses' clinical judgement alone due to serious risks of bias and insufficient sample size. Second, it seems infeasible to assess this impact by means of rigorous experimental studies since sample size would become extremely high if likely threats to validity and power are properly taken into account. Third, means of evidence linkages seem to currently be the most promising approaches for evaluating the clinical efficacy and safety of PURAS-aided risk assessment. With this kind of secondary research, the downstream effect of use of PURAS on pressure ulcer incidence could be modelled by combining best available evidence for single parts of this pathway. However, to yield reliable modelling

  6. Fast underdetermined BSS architecture design methodology for real time applications.

    Science.gov (United States)

    Mopuri, Suresh; Reddy, P Sreenivasa; Acharyya, Amit; Naik, Ganesh R

    2015-01-01

    In this paper, we propose a high speed architecture design methodology for the Under-determined Blind Source Separation (UBSS) algorithm using our recently proposed high speed Discrete Hilbert Transform (DHT) targeting real time applications. In UBSS algorithm, unlike the typical BSS, the number of sensors are less than the number of the sources, which is of more interest in the real time applications. The DHT architecture has been implemented based on sub matrix multiplication method to compute M point DHT, which uses N point architecture recursively and where M is an integer multiples of N. The DHT architecture and state of the art architecture are coded in VHDL for 16 bit word length and ASIC implementation is carried out using UMC 90 - nm technology @V DD = 1V and @ 1MHZ clock frequency. The proposed architecture implementation and experimental comparison results show that the DHT design is two times faster than state of the art architecture.

  7. Unified methodology for fire safety assessment and optimal design

    Energy Technology Data Exchange (ETDEWEB)

    Shetty, N.K.; Deaves, D.M.; Gierlinski, J.T. [WS Atkins Consultants Ltd., Epsom (United Kingdom); Dogliani, M. [Registro Italiano Navale, Genova (Italy)

    1996-12-31

    The paper presents a unified, fully-probabilistic approach to fire safety assessment and optimal design of fire protection on offshore topside structures. The methodology has been developed by integrating Quantitative Risk Analysis (QRA) techniques with the modern methods of Structural System Reliability Analysis (SRA) and Reliability Based Design Optimization (RBDO). The integration has been achieved by using platform-specific extended event-trees which model in detail the escalation paths leading to the failure of Temporary Refuge (TR), Escape, Evacuation and Rescue (EER) systems or structural collapse of the topside. Probabilities of events for which historical data are not generally available are calculated using structural reliability methods. The optimization of fire protection is performed such that the total expected cost of the protection system and the cost of failure of the platform (loss of life, loss of asset, environmental damage) is minimized while satisfying reliability constraints.

  8. An Integrated Methodology for Emulsified Formulated Product Design

    DEFF Research Database (Denmark)

    Mattei, Michele

    and generated; and an algorithm for the model - based design of emulsified solvent mixtures has been developed. All these tools have b een im- plemented as a new template in the virtual Product - Process Design laboratory software. To illustrate the application of the proposed methodology, three case studies......The consumer oriented chemical based products are used every day by millions of people. They are structured products constituted of numerous chemicals, and many of them, especially household and personal care products, are emulsions where active ingredients, solvents, additives and surfactants...... models have been retrieved and organized in a model library; new property models have been developed for a set of thermo - physical properties of surfactants; a robust, system atic knowledge - base has been developed in relation to emulsified formulated products; chem- ical databases have been improved...

  9. Design Methodology And Performance Studies Of A Flexible Electrotextile Surface

    Directory of Open Access Journals (Sweden)

    Kayacan Ozan

    2015-09-01

    Full Text Available ‘The smart textiles’ concept has to develop products based not only on design, fashion and comfort but also in terms of functions. The novel electro-textiles in the market open up new trends in smart and interactive gadgets. ‘Easy to care and durability’ properties are among the most important features of these products. On the other hand, wearable electronic knitwear has been gaining the attention of both researchers and industrial sectors. Combining knitting technology with electronics may become a dominant trend in the future because of the wide application possibilities. This research is concerned primarily with the design methodology of knitted fabrics containing electrically conductive textiles and especially in-use performance studies. The structural characteristics of the fabrics have been evaluated to enhance the performance properties.

  10. A New Methodology of Design and Development of Serious Games

    Directory of Open Access Journals (Sweden)

    André F. S. Barbosa

    2014-01-01

    Full Text Available The development of a serious game requires perfect knowledge of the learning domain to obtain the desired results. But it is also true that this may not be enough to develop a successful serious game. First of all, the player has to feel that he is playing a game where the learning is only a consequence of the playing actions. Otherwise, the game is viewed as boring and not as a fun activity and engaging. For example, the player can catch some items in the scenario and then separate them according to its type (i.e., recycle them. Thus, the main action for player is catching the items in the scenario where the recycle action is a second action, which is viewed as a consequence of the first action. Sometimes, the game design relies on a detailed approach based on the ideas of the developers because some educational content are difficult to integrate in the games, while maintaining the fun factor in the first place. In this paper we propose a new methodology of design and development of serious games that facilitates the integration of educational contents in the games. Furthermore, we present a serious game, called “Clean World”, created using this new methodology.

  11. A design methodology for biologically inspired dry fibrillar adhesives

    Science.gov (United States)

    Aksak, Burak

    Realization of the unique aspects of gecko adhesion and incorporating these aspects into a comprehensive design methodology is essential to enable fabrication of application oriented gecko-inspired dry fibrillar adhesives. To address the need for such a design methodology, we propose a fibrillar adhesion model that evaluates the effect of fiber dimensions and material on adhesive performance of fiber arrays. A fibrillar adhesion model is developed to predict the adhesive characteristics of an array of fibrillar structures, and quantify the effect of fiber length, radius, spacing, and material. Photolithography techniques were utilized to fabricate elastomer microfiber arrays. Fibers that are fabricated from stiff SU-8 photoresist are used to fabricate a flexible negative mold that facilitates fabrication of fiber arrays from various elastomers with high yield. The tips of the cylindrical fibers are modified to mushroom-like tip shapes. Adhesive strengths in excess of 100 kPa is obtained with mushroom tipped elastomer microfibers. Vertically aligned carbon nanofibers (VACNFs) are utilized as enhanced friction materials by partially embedding inside soft polyurethanes. Friction coefficients up to 1 were repeatedly obtained from the resulting VACNF composite structures. A novel fabrication method is used to attach Poly(n-butyl acrylate) (PBA) molecular brush-like structures on the surface of polydimethylsiloxane (PDMS). These brushes are grown on unstructured PDMS and PDMS fibers with mushroom tips. Pull-off force is enhanced by up to 7 times with PBA brush grafted micro-fiber arrays over unstructured PDMS substrate. Adhesion model, initially developed for curved smooth surfaces, is extended to self-affine fractal surfaces to better reflect the adhesion performance of fiber arrays on natural surfaces. Developed adhesion model for fiber arrays is used in an optimization scheme which estimates optimal design parameters to obtain maximum adhesive strength on a given

  12. A Combined Heuristic and Indicator-based Methodology for Design of Sustainable Chemical Process Plants

    DEFF Research Database (Denmark)

    Halim, Iskandar; Carvalho, Ana; Srinivasan, Rajagopalan;

    2011-01-01

    The current emphasis on sustainable production has prompted chemical plants to minimize raw material and energy usage without compromising on economics. While computer tools are available to assistin sustainability assessment, their applications are constrained to a specific domain of the design...... synthesis problem. This paper outlines a design synthesis strategy that integrates two computer methodologies – ENVOPExpert and SustainPro – for simultaneous generation, analysis, evaluation, and optimization of sustainable process alternatives. ENVOPExpert diagnoses waste sources, identifies alternatives......, comprehensive generation of design alternatives, and effective reduction of the optimization search space. The frame-work is illustrated using anacetone process and a methanol and dimethyl ether production case study....

  13. A symbolic methodology to improve disassembly process design.

    Science.gov (United States)

    Rios, Pedro; Blyler, Leslie; Tieman, Lisa; Stuart, Julie Ann; Grant, Ed

    2003-12-01

    Millions of end-of-life electronic components are retired annually due to the proliferation of new models and their rapid obsolescence. The recovery of resources such as plastics from these goods requires their disassembly. The time required for each disassembly and its associated cost is defined by the operator's familiarity with the product design and its complexity. Since model proliferation serves to complicate an operator's learning curve, it is worthwhile to investigate the benefits to be gained in a disassembly operator's preplanning process. Effective disassembly process design demands the application of green engineering principles, such as those developed by Anastas and Zimmerman (Environ. Sci. Technol. 2003, 37, 94A-101A), which include regard for product complexity, structural commonality, separation energy, material value, and waste prevention. This paper introduces the concept of design symbolsto help the operator more efficiently survey product complexity with respect to location and number of fasteners to remove a structure that is common to all electronics: the housing. With a sample of 71 different computers, printers, and monitors, we demonstrate that appropriate symbols reduce the total disassembly planning time by 13.2 min. Such an improvement could well make efficient the separation of plastic that would otherwise be destined for waste-to-energy or landfill. The symbolic methodology presented may also improve Design for Recycling and Design for Maintenance and Support.

  14. Clinical Research Methodology 1: Study Designs and Methodologic Sources of Error.

    Science.gov (United States)

    Sessler, Daniel I; Imrey, Peter B

    2015-10-01

    Clinical research can be categorized by the timing of data collection: retrospective or prospective. Clinical research also can be categorized by study design. In case-control studies, investigators compare previous exposures (including genetic and other personal factors, environmental influences, and medical treatments) among groups distinguished by later disease status (broadly defined to include the development of disease or response to treatment). In cohort studies, investigators compare subsequent incidences of disease among groups distinguished by one or more exposures. Comparative clinical trials are prospective cohort studies that compare treatments assigned to patients by the researchers. Most errors in clinical research findings arise from 5 largely distinguishable classes of methodologic problems: selection bias, confounding, measurement bias, reverse causation, and excessive chance variation.

  15. Current trends in high temperature design

    Energy Technology Data Exchange (ETDEWEB)

    Marriott, D.L. (Illinois Univ., Urbana, IL (United States). Dept. of Mechanical Engineering)

    1992-01-01

    A review of high temperature design guidelines has been carried out in preparation for designing a solar storage module for the Freedom Spacelab. Three major guidelines, N47, R5 and RCC-MR form the basis of the survey. The main issues with current, mature design in the power industry appear to be adequately covered by these guidelines. A significant finding is that long established models of material damage have survived the test of time very well. A new design regime referred to as Very High Temperature Design (VHTD) is identified. The characteristics of this regime are changing material properties which require some changes in philosophy in drafting of future codes, particularly in regard to definitions of yield strengths and other design allowables. Finally, there is some discussion of the more general use of the stress/strain plane, e.g. isochronous curves, for representation of very complex material constitutive behaviour. A concept called the 'Relaxation Locus', which summarizes essential local constrained component behavior, is introduced and its application to high temperature design problems is discussed briefly. (author).

  16. Superconducting Fault Current Limiter optimized design

    Energy Technology Data Exchange (ETDEWEB)

    Tixador, Pascal, E-mail: Pascal.Tixador@grenoble-inp.fr [Univ. Grenoble Alpes, G2Elab – Institut Néel, F-38000 Grenoble (France); CNRS, G2Elab – Institut Néel, F-38000 Grenoble (France); Badel, Arnaud [CNRS, G2Elab – Institut Néel, F-38000 Grenoble (France)

    2015-11-15

    Highlights: • A low cost design of YBCO Fault Current Limiter. • A high resistance conductor for reduced length. • An asymmetrical YBCO conductor (injection and AC losses). • A thickness suitable for non destructive hot spots. - Abstract: The SuperConducting Fault Current Limiter (SCFCL) appears as one of the most promising SC applications for the electrical grids. Despite its advantages and many successful field experiences the market of SCFCL has difficulties to take off even if the first orders for permanent operation in grids are taken. The analytical design of resistive SCFCL will be discussed with the objective to reduce the quantity of SC conductor (length and section) to be more cost-effective. For that the SC conductor must have a high resistivity in normal state. It can be achieved by using high resistivity alloy for shunt, such as Hastelloy®. One of the most severe constraint is that the SCFCL should operate safely for any faults, especially those with low prospective short-circuit currents. This constraint requires to properly design the thickness of the SC tape in order to limit the hot spot temperature. An operation at 65 K appears as very interesting since it decreases the SC cost at least by a factor 2 with a simple LN2 cryogenics. Taking into account the cost reduction in a near future, the SC conductor cost could be rather low, half a dollar per kV A.

  17. Building Design, Durability, Maintenance: Methodology for the Durability Forecasting

    Directory of Open Access Journals (Sweden)

    Riccardo Pollo

    2014-05-01

    Full Text Available The paper describes a research based on the use of the software BIM (Building Information Modeling which is associated with an experimental procedure of the evaluation of durability and the life cycle based on FMEA (Failure Mode and Effects Analysis, one of the methods for durability assessment indicated by the ISO 15686-1 standard. The study shows the methodology and develops a case study on the refurbishment of an old building and discusses its outcome. The experiment on one side illustrates the utility of the analytical approach of FMEA and on the other side the difficulty to use different data and information to be considered in the durability evaluation carried out by the designer  based on the expert assessment. The role of the experts is to design a model and to assess the criticality of each event and to define the relationship between the causes and effects on building elements function. The designer has to define the environmental conditions of the site, the specifications of the material used, the skills of workmanship. The study has shown a quite realistic outcome and significant indications for the designer. Such a result suggests the development of the research.

  18. Current fusion power plant design concepts

    Energy Technology Data Exchange (ETDEWEB)

    Gore, B.F.; Murphy, E.S.

    1976-09-01

    Nine current U.S. designs for fusion power plants are described in this document. Summary tabulations include a tenth concept, for which the design document was unavailable during preparation of the descriptions. The information contained in the descriptions was used to define an envelope of fusion power plant characteristics which formed the basis for definition of reference first commercial fusion power plant design. A brief prose summary of primary plant features introduces each of the descriptions contained in the body of this document. In addition, summary tables are presented. These tables summarize in side-by-side fashion, plant parameters, processes, combinations of materials used, requirements for construction materials, requirements for replacement materials during operation, and production of wastes.

  19. A METHODOLOGY FOR DESIGN SPACE EXPLORATION OF REAL-TIME LOCATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    R. Passerone

    2015-07-01

    Full Text Available Scope of Research. This paper deals with the problem of design space exploration for a particular class of networked embedded systems called Real-Time Location Systems (RTLS. Methods. The paper contains a clear and detailed plan of anongoing research and could be considered as a review, a vision and a statement of objectives. Analytical and formal methods, simulation and automated verification will be involved in the research. Main Results. Analysis of the state of the art (current design flow, existing simulation tools and verification techniques has revealed several limitations for performing efficientdesign space exploration of RTLS, especially for safety-critical applications. The review part of the paper also contains a clear problem statement. The main outcome of this research is the proposed vision of a novel methodology for determining the best-suited technology and its configuration from the space of potential solutions. In particular, it is planned to extend an existing simulation framework and apply automated verification techniques. The latter will be used for checking simulation results and also for exploring different system configuration alternatives, that is, to optimize the design, which is a novel approach. A case study for validating the methodology is also proposed. Practical Significance. The proposed methodology will highly increase the breadth of design space exploration of RTLS as well as the confidence on taken design decisions. It will also contribute to optimizing the design.

  20. Methodology, Algorithms, and Emerging Tool for Automated Design of Intelligent Integrated Multi-Sensor Systems

    Directory of Open Access Journals (Sweden)

    Andreas König

    2009-11-01

    Full Text Available The emergence of novel sensing elements, computing nodes, wireless communication and integration technology provides unprecedented possibilities for the design and application of intelligent systems. Each new application system must be designed from scratch, employing sophisticated methods ranging from conventional signal processing to computational intelligence. Currently, a significant part of this overall algorithmic chain of the computational system model still has to be assembled manually by experienced designers in a time and labor consuming process. In this research work, this challenge is picked up and a methodology and algorithms for automated design of intelligent integrated and resource-aware multi-sensor systems employing multi-objective evolutionary computation are introduced. The proposed methodology tackles the challenge of rapid-prototyping of such systems under realization constraints and, additionally, includes features of system instance specific self-correction for sustained operation of a large volume and in a dynamically changing environment. The extension of these concepts to the reconfigurable hardware platform renders so called self-x sensor systems, which stands, e.g., for self-monitoring, -calibrating, -trimming, and -repairing/-healing systems. Selected experimental results prove the applicability and effectiveness of our proposed methodology and emerging tool. By our approach, competitive results were achieved with regard to classification accuracy, flexibility, and design speed under additional design constraints.

  1. Towards a Methodology for the Design of Multimedia Public Access Interfaces.

    Science.gov (United States)

    Rowley, Jennifer

    1998-01-01

    Discussion of information systems methodologies that can contribute to interface design for public access systems covers: the systems life cycle; advantages of adopting information systems methodologies; soft systems methodologies; task-oriented approaches to user interface design; holistic design, the Star model, and prototyping; the…

  2. Towards a Methodology for the Design of Multimedia Public Access Interfaces.

    Science.gov (United States)

    Rowley, Jennifer

    1998-01-01

    Discussion of information systems methodologies that can contribute to interface design for public access systems covers: the systems life cycle; advantages of adopting information systems methodologies; soft systems methodologies; task-oriented approaches to user interface design; holistic design, the Star model, and prototyping; the…

  3. A methodology for designing flexible multi-generation systems

    DEFF Research Database (Denmark)

    Lythcke-Jørgensen, Christoffer Ernst; Viana Ensinas, Adriano; Münster, Marie

    2016-01-01

    An FMG (flexible multi-generation system) consists of integrated and flexibly operated facilities that provide multiple links between the various layers of the energy system. FMGs may facilitate integration and balancing of fluctuating renewable energy sources in the energy system in a cost...... is based on consideration of the following points: Selection, location and dimensioning of processes; systematic heat and mass integration; flexible operation optimization with respect to both short-term market fluctuations and long-term energy system development; global sensitivity and uncertainty...... analysis; biomass supply chains; variable part-load performance; and multi-objective optimization considering economic and environmental performance. Tested in a case study, the methodology is proved effective in screening the solution space for efficient FMG designs, in assessing the importance...

  4. Sonic Boom Mitigation Through Aircraft Design and Adjoint Methodology

    Science.gov (United States)

    Rallabhandi, Siriam K.; Diskin, Boris; Nielsen, Eric J.

    2012-01-01

    This paper presents a novel approach to design of the supersonic aircraft outer mold line (OML) by optimizing the A-weighted loudness of sonic boom signature predicted on the ground. The optimization process uses the sensitivity information obtained by coupling the discrete adjoint formulations for the augmented Burgers Equation and Computational Fluid Dynamics (CFD) equations. This coupled formulation links the loudness of the ground boom signature to the aircraft geometry thus allowing efficient shape optimization for the purpose of minimizing the impact of loudness. The accuracy of the adjoint-based sensitivities is verified against sensitivities obtained using an independent complex-variable approach. The adjoint based optimization methodology is applied to a configuration previously optimized using alternative state of the art optimization methods and produces additional loudness reduction. The results of the optimizations are reported and discussed.

  5. SSME Investment in Turbomachinery Inducer Impeller Design Tools and Methodology

    Science.gov (United States)

    Zoladz, Thomas; Mitchell, William; Lunde, Kevin

    2010-01-01

    Within the rocket engine industry, SSME turbomachines are the de facto standards of success with regard to meeting aggressive performance requirements under challenging operational environments. Over the Shuttle era, SSME has invested heavily in our national inducer impeller design infrastructure. While both low and high pressure turbopump failures/anomaly resolution efforts spurred some of these investments, the SSME program was a major benefactor of key areas of turbomachinery inducer-impeller research outside of flight manifest pressures. Over the past several decades, key turbopump internal environments have been interrogated via highly instrumented hot-fire and cold-flow testing. Likewise, SSME has sponsored the advancement of time accurate and cavitating inducer impeller computation fluid dynamics (CFD) tools. These investments together have led to a better understanding of the complex internal flow fields within aggressive high performing inducers and impellers. New design tools and methodologies have evolved which intend to provide confident blade designs which strike an appropriate balance between performance and self induced load management.

  6. Methodological design of the National Health and Nutrition Survey 2016

    Directory of Open Access Journals (Sweden)

    Martín Romero-Martínez

    2017-05-01

    Full Text Available Objective. Describe the design methodology of the halfway health and nutrition national survey (Ensanut-MC 2016. Materials and methods. The Ensanut-MC is a national probabilistic survey whose objective population are the in­habitants of private households in Mexico. The sample size was determined to make inferences on the urban and rural areas in four regions. Describes main design elements: target population, topics of study, sampling procedure, measurement procedure and logistics organization. Results. A final sample of 9 479 completed household interviews, and a sample of 16 591 individual interviews. The response rate for households was 77.9%, and the response rate for individuals was 91.9%. Conclusions. The Ensanut-MC probabilistic design allows valid statistical inferences about interest parameters for Mexico´s public health and nutrition, specifically on over­weight, obesity and diabetes mellitus. Updated information also supports the monitoring, updating and formulation of new policies and priority programs.

  7. An NAFP Project: Use of Object Oriented Methodologies and Design Patterns to Refactor Software Design

    Science.gov (United States)

    Shaykhian, Gholam Ali; Baggs, Rhoda

    2007-01-01

    In the early problem-solution era of software programming, functional decompositions were mainly used to design and implement software solutions. In functional decompositions, functions and data are introduced as two separate entities during the design phase, and are followed as such in the implementation phase. Functional decompositions make use of refactoring through optimizing the algorithms, grouping similar functionalities into common reusable functions, and using abstract representations of data where possible; all these are done during the implementation phase. This paper advocates the usage of object-oriented methodologies and design patterns as the centerpieces of refactoring software solutions. Refactoring software is a method of changing software design while explicitly preserving its external functionalities. The combined usage of object-oriented methodologies and design patterns to refactor should also benefit the overall software life cycle cost with improved software.

  8. Development of probabilistic rigid pavement design methodologies for military airfields

    Science.gov (United States)

    Witczak, M. W.; Uzan, J.; Johnson, M.

    1983-12-01

    The current Corps of Engineers design procedures for rigid airfield pavements is based on the Westergaard free edge stress slab theory, and a proposed procedure is based on the multilayer elastic theory. These two design procedures have been expanded to airfield pavement designs expressed in probabilistic and reliability terms. Further developments were required in these procedures to make the analysis more practicable. Two major investigations were conducted: (1) Evaluation and use of the composite modulus of elasticity for layers beneath the rigid pavement, and (2) Evaluation of the maximum tensile stress at the bottom of the slab for different aircraft types. Derivations obtained from the investigation of the composite modulus and maximum tensile stress are reported and are included in computer programs for probabilistic/reliability analysis of rigid pavements. The approximate closed form (Taylor series expansion) is utilized. Example runs of the computer program are presented.

  9. Methodology for bioclimatic design; Metodologia para el diseno bioclimatico

    Energy Technology Data Exchange (ETDEWEB)

    Morillon Galvez, David [Instituto de Ingenieria de la UNAM, Mexico, D.F. (Mexico)

    2000-07-01

    A methodology for natural air conditioning of buildings is presented; bioclimatic architecture, in order to contribute to the suitable use of components of the building (walls, ceilings, floors, orientations, etc.) that when interacting with the environment takes advantage of it, without deterioration of the same, obtaining energy efficient designs. As well as an analysis of the elements and factors that the architecture must have to be sustainable; an adequate design to the environment, saving and efficient use of energy, the use of alternating energies by means of ecotechnologies and the self-sufficiency. [Spanish] Se presenta una metodologia para la climatizacion natural de edificios; arquitectura bioclimatica, con el objetivo de aportar al uso adecuado de componentes del edificio (muros, techos, pisos, orientaciones, etc.) que al interactuar con el ambiente tome ventaja de el, sin deterioro del mismo, logrando disenos energeticamente eficientes. Asi como un analisis de los elementos y factores que debe tener la arquitectura para ser sustentable; un diseno adecuado al ambiente, ahorro y uso eficiente de la energia, el uso de energias alternas mediante ecotecnologias y la autosuficiencia.

  10. Superconducting Fault Current Limiter optimized design

    Science.gov (United States)

    Tixador, Pascal; Badel, Arnaud

    2015-11-01

    The SuperConducting Fault Current Limiter (SCFCL) appears as one of the most promising SC applications for the electrical grids. Despite its advantages and many successful field experiences the market of SCFCL has difficulties to take off even if the first orders for permanent operation in grids are taken. The analytical design of resistive SCFCL will be discussed with the objective to reduce the quantity of SC conductor (length and section) to be more cost-effective. For that the SC conductor must have a high resistivity in normal state. It can be achieved by using high resistivity alloy for shunt, such as Hastelloy®. One of the most severe constraint is that the SCFCL should operate safely for any faults, especially those with low prospective short-circuit currents. This constraint requires to properly design the thickness of the SC tape in order to limit the hot spot temperature. An operation at 65 K appears as very interesting since it decreases the SC cost at least by a factor 2 with a simple LN2 cryogenics. Taking into account the cost reduction in a near future, the SC conductor cost could be rather low, half a dollar per kV A.

  11. Evaluating some Reliability Analysis Methodologies in Seismic Design

    Directory of Open Access Journals (Sweden)

    A. E. Ghoulbzouri

    2011-01-01

    Full Text Available Problem statement: Accounting for uncertainties that are present in geometric and material data of reinforced concrete buildings is performed in this study within the context of performance based seismic engineering design. Approach: Reliability of the expected performance state is assessed by using various methodologies based on finite element nonlinear static pushover analysis and specialized reliability software package. Reliability approaches that were considered included full coupling with an external finite element code and surface response based methods in conjunction with either first order reliability method or importance sampling method. Various types of probability distribution functions that model parameters uncertainties were introduced. Results: The probability of failure according to the used reliability analysis method and to the selected distribution of probabilities was obtained. Convergence analysis of the importance sampling method was performed. The required duration of analysis as function of the used reliability method was evaluated. Conclusion/Recommendations: It was found that reliability results are sensitive to the used reliability analysis method and to the selected distribution of probabilities. Durations of analysis for coupling methods were found to be higher than those associated to surface response based methods; one should however include time needed to derive these lasts. For the reinforced concrete building considered in this study, it was found that significant variations exist between all the considered reliability methodologies. The full coupled importance sampling method is recommended, but the first order reliability method applied on a surface response model can be used with good accuracy. Finally, the distributions of probabilities should be carefully identified since giving the mean and the standard deviation were found to be insufficient.

  12. New methods, new methodology: Advanced CFD in the Snecma turbomachinery design process

    Science.gov (United States)

    Vuillez, Christophe; Petot, Bertrand

    1994-05-01

    CFD tools represent a significant source of improvements in the design process of turbomachinery components, leading to higher performances, cost and cycle savings as well as lower associated risks. Such methods are the backbone of compressor and turbine design methodologies at Snecma. In the 80's, the use of 3D Euler solvers was a key factor in designing fan blades with very high performance level. Counter rotating high speed propellers designed with this methodology reached measured performances very close to their ambitious objective from the first test series. In the late 80's and the beginning of the 90's, new, more powerful methods were rapidly developed and are now commonly used in the design process: a quasi-3D, compressible, transonic inverse method; quasi-3D and 3D Navier-Stokes solvers; 3D unsteady Euler solvers. As an example, several hundred 3D Navier-Stokes computations are run yearly for the design of low and high pressure compressor and turbine blades. In addition to their modelling capabilities, the efficient use of such methods in the design process comes from their close integration in the global methodology and from an adequate exploitation environment. Their validation, their calibration, and the correlations between different levels of modelling are of critical importance to an actual improvement in design know-how. The integration of different methods in the design process is described. Several examples of application illustrate their practical utilization. Comparisons between computational results and test results show their capabilities as well as their present limitations. The prospects linked to new developments currently under way are discussed.

  13. Database Design Methodology and Database Management System for Computer-Aided Structural Design Optimization.

    Science.gov (United States)

    1984-12-01

    1983). Several researchers Lillehagen and Dokkar (1982), Grabowski, Eigener and Ranch (1978), and Eberlein and Wedekind (1982) have worked on database...Proceedings of International Federation of Information Processing. pp. 335-366. Eberlein, W. and Wedekind , H., 1982, "A Methodology for Embedding Design

  14. We!Design: A Student-Centred Participatory Methodology for the Design of Educational Applications

    Science.gov (United States)

    Triantafyllakos, George N.; Palaigeorgiou, George E.; Tsoukalas, Ioannis A.

    2008-01-01

    The development of educational applications has always been a challenging and complex issue, mainly because of the complications imposed by the cognitive and psychological aspects of student-computer interactions. This article presents a methodology, named We!Design, that tries to encounter the complexity of educational applications development…

  15. Supporting Space Systems Design via Systems Dependency Analysis Methodology

    Science.gov (United States)

    Guariniello, Cesare

    assess the behavior of each system based on its internal status and on the topology of its dependencies on systems connected to it. Designers and decision makers can therefore quickly analyze and explore the behavior of complex systems and evaluate different architectures under various working conditions. The methods support educated decision making both in the design and in the update process of systems architecture, reducing the need to execute extensive simulations. In particular, in the phase of concept generation and selection, the information given by the methods can be used to identify promising architectures to be further tested and improved, while discarding architectures that do not show the required level of global features. The methods, when used in conjunction with appropriate metrics, also allow for improved reliability and risk analysis, as well as for automatic scheduling and re-scheduling based on the features of the dependencies and on the accepted level of risk. This dissertation illustrates the use of the two methods in sample aerospace applications, both in the operational and in the developmental domain. The applications show how to use the developed methodology to evaluate the impact of failures, assess the criticality of systems, quantify metrics of interest, quantify the impact of delays, support informed decision making when scheduling the development of systems and evaluate the achievement of partial capabilities. A larger, well-framed case study illustrates how the Systems Operational Dependency Analysis method and the Systems Developmental Dependency Analysis method can support analysis and decision making, at the mid and high level, in the design process of architectures for the exploration of Mars. The case study also shows how the methods do not replace the classical systems engineering methodologies, but support and improve them.

  16. A systematic methodology for design of tailor-made blended products

    DEFF Research Database (Denmark)

    Yunus, Nor Alafiza Binti; Gernaey, Krist; Woodley, John

    2014-01-01

    A systematic methodology for design of tailor-made blended products has been developed. In tailor-made blended products, one identifies the product needs and matches them by blending different chemicals. The systematic methodology has four main tasks. First, the design problem is defined: the pro......, the methodology is highlighted through two case studies involving gasoline blends and lubricant base oils....

  17. How Is Working Memory Training Likely to Influence Academic Performance? Current Evidence and Methodological Considerations.

    Science.gov (United States)

    Bergman Nutley, Sissela; Söderqvist, Stina

    2017-01-01

    Working memory (WM) is one of our core cognitive functions, allowing us to keep information in mind for shorter periods of time and then work with this information. It is the gateway that information has to pass in order to be processed consciously. A well-functioning WM is therefore crucial for a number of everyday activities including learning and academic performance (Gathercole et al., 2003; Bull et al., 2008), which is the focus of this review. Specifically, we will review the research investigating whether improving WM capacity using Cogmed WM training can lead to improvements on academic performance. Emphasis is given to reviewing the theoretical principles upon which such investigations rely, in particular the complex relation between WM and mathematical and reading abilities during development and how these are likely to be influenced by training. We suggest two possible routes in which training can influence academic performance, one through an effect on learning capacity which would thus be evident with time and education, and one through an immediate effect on performance on reading and mathematical tasks. Based on the theoretical complexity described we highlight some methodological issues that are important to take into consideration when designing and interpreting research on WM training and academic performance, but that are nonetheless often overlooked in the current research literature. Finally, we will provide some suggestions for future research for advancing the understanding of WM training and its potential role in supporting academic attainment.

  18. How Is Working Memory Training Likely to Influence Academic Performance? Current Evidence and Methodological Considerations

    Science.gov (United States)

    Bergman Nutley, Sissela; Söderqvist, Stina

    2017-01-01

    Working memory (WM) is one of our core cognitive functions, allowing us to keep information in mind for shorter periods of time and then work with this information. It is the gateway that information has to pass in order to be processed consciously. A well-functioning WM is therefore crucial for a number of everyday activities including learning and academic performance (Gathercole et al., 2003; Bull et al., 2008), which is the focus of this review. Specifically, we will review the research investigating whether improving WM capacity using Cogmed WM training can lead to improvements on academic performance. Emphasis is given to reviewing the theoretical principles upon which such investigations rely, in particular the complex relation between WM and mathematical and reading abilities during development and how these are likely to be influenced by training. We suggest two possible routes in which training can influence academic performance, one through an effect on learning capacity which would thus be evident with time and education, and one through an immediate effect on performance on reading and mathematical tasks. Based on the theoretical complexity described we highlight some methodological issues that are important to take into consideration when designing and interpreting research on WM training and academic performance, but that are nonetheless often overlooked in the current research literature. Finally, we will provide some suggestions for future research for advancing the understanding of WM training and its potential role in supporting academic attainment.

  19. Designing spectrum-splitting dichroic filters to optimize current-matched photovoltaics.

    Science.gov (United States)

    Miles, Alexander; Cocilovo, Byron; Wheelwright, Brian; Pan, Wei; Tweet, Doug; Norwood, Robert A

    2016-03-10

    We have developed an approach for designing a dichroic coating to optimize performance of current-matched multijunction photovoltaic cells while diverting unused light. By matching the spectral responses of the photovoltaic cells and current matching them, substantial improvement to system efficiencies is shown to be possible. A design for use in a concentrating hybrid solar collector was produced by this approach, and is presented. Materials selection, design methodology, and tilt behavior on a curved substrate are discussed.

  20. A knowledge management methodology for the integrated assessment of WWTP configurations during conceptual design.

    Science.gov (United States)

    Garrido-Baserba, M; Reif, R; Rodriguez-Roda, I; Poch, M

    2012-01-01

    The current complexity involved in wastewater management projects is arising as the XXI century sets new challenges leading towards a more integrated plant design. In this context, the growing number of innovative technologies, stricter legislation and the development of new methodological approaches make it difficult to design appropriate flow schemes for new wastewater projects. Thus, new tools are needed for the wastewater treatment plant (WWTP) conceptual design using integrated assessment methods in order to include different types of objectives at the same time i.e. environmental, economical, technical, and legal. Previous experiences used the decision support system (DSS) methodology to handle the specific issues related to wastewater management, for example, the design of treatment facilities for small communities. However, tools developed for addressing the whole treatment process independently of the plant size, capable of integrating knowledge from many different areas, including both conventional and innovative technologies are not available. Therefore, the aim of this paper is to present and describe an innovative knowledge-based methodology that handles the conceptual design of WWTP process flow-diagrams (PFDs), satisfying a vast number of different criteria. This global approach is based on a hierarchy of decisions that uses the information contained in knowledge bases (KBs) with the aim of automating the generation of suitable WWTP configurations for a specific scenario. Expert interviews, legislation, specialized literature and engineering experience have been integrated within the different KBs, which indeed constitute one of the main highlights of this work. Therefore, the methodology is presented as a valuable tool which provides customized PFD for each specific case, taking into account process unit interactions and the user specified requirements and objectives.

  1. Proposal of a methodology for the design of communication strategies.

    Directory of Open Access Journals (Sweden)

    Mislany Hernández Aguiar

    2009-12-01

    Full Text Available In this work the topic of Strategies of Communication is approached from the point of view of Cuban managerial improvement process. The topic deal with two models or paradigms: the transmissive, where the diffusion or transmission of information is conceived versus communication and the persuasive which on the other hand refers to the modification of behaviors, opinions, attitudes and that demands knowledge about the audience. It is clarified that persuasive communication is the theoretical and methodological basis of communication strategies that constitute the set of ways and modes of communication that have the objective to establish an effective communication of ideas, products or services. In this work is mentioned different criteria that exist regarding the elements that should be treated in the strategy of communication and the proposal of steps that according to the author must not be excluded in it, such as: definition of communicative or communication objectives, determination of audiences, definition of communication strategies, design of the action plan, control and feedback.

  2. A Research Methodology for Green IT Systems Based on WSR and Design Science: The Case of a Chinese Company

    Science.gov (United States)

    Zhong, Yinghong; Liu, Hongwei

    Currently green IT has been a hotspot in both practice and research fields. Much progress has been made in the aspect of green technologies. However, researchers and designers could not simply build up a green IT system from technological aspect, which is normally considered as a wicked problem. This paper puts forward a research methodology for green IT systems by introducing WSR and design science. This methodology absorbs essence from soft systems methodology and action research. It considers the research, design and building of green IT systems from a systemic perspective which can be divided into as technological dimension, management dimension and human dimension. This methodology consists of 7 iterated stages. Each stage is presented and followed by a case study from a Chinese company.

  3. A Platform-Based Methodology for System-Level Mixed-Signal Design

    Directory of Open Access Journals (Sweden)

    Alberto Sangiovanni-Vincentelli

    2010-01-01

    Full Text Available The complexity of today's embedded electronic systems as well as their demanding performance and reliability requirements are such that their design can no longer be tackled with ad hoc techniques while still meeting tight time to-market constraints. In this paper, we present a system level design approach for electronic circuits, utilizing the platform-based design (PBD paradigm as the natural framework for mixed-domain design formalization. In PBD, a meet-in-the-middle approach allows systematic exploration of the design space through a series of top-down mapping of system constraints onto component feasibility models in a platform library, which is based on bottom-up characterizations. In this framework, new designs can be assembled from the precharacterized library components, giving the highest priority to design reuse, correct assembly, and efficient design flow from specifications to implementation. We apply concepts from design centering to enforce robustness to modeling errors as well as process, voltage, and temperature variations, which are currently plaguing embedded system design in deep-submicron technologies. The effectiveness of our methodology is finally shown on the design of a pipeline A/D converter and two receiver front-ends for UMTS and UWB communications.

  4. Methodology for CFD Design Analysis of National Launch System Nozzle Manifold

    Science.gov (United States)

    Haire, Scot L.

    1993-01-01

    The current design environment dictates that high technology CFD (Computational Fluid Dynamics) analysis produce quality results in a timely manner if it is to be integrated into the design process. The design methodology outlined describes the CFD analysis of an NLS (National Launch System) nozzle film cooling manifold. The objective of the analysis was to obtain a qualitative estimate for the flow distribution within the manifold. A complex, 3D, multiple zone, structured grid was generated from a 3D CAD file of the geometry. A Euler solution was computed with a fully implicit compressible flow solver. Post processing consisted of full 3D color graphics and mass averaged performance. The result was a qualitative CFD solution that provided the design team with relevant information concerning the flow distribution in and performance characteristics of the film cooling manifold within an effective time frame. Also, this design methodology was the foundation for a quick turnaround CFD analysis of the next iteration in the manifold design.

  5. Design of a rotary reactor for chemical-looping combustion. Part 1: Fundamentals and design methodology

    KAUST Repository

    Zhao, Zhenlong

    2014-04-01

    Chemical-looping combustion (CLC) is a novel and promising option for several applications including carbon capture (CC), fuel reforming, H 2 generation, etc. Previous studies demonstrated the feasibility of performing CLC in a novel rotary design with micro-channel structures. In the reactor, a solid wheel rotates between the fuel and air streams at the reactor inlet, and depleted air and product streams at exit. The rotary wheel consists of a large number of micro-channels with oxygen carriers (OC) coated on the inner surface of the channel walls. In the CC application, the OC oxidizes the fuel while the channel is in the fuel zone to generate undiluted CO2, and is regenerated while the channel is in the air zone. In this two-part series, the effect of the reactor design parameters is evaluated and its performance with different OCs is compared. In Part 1, the design objectives and criteria are specified and the key parameters controlling the reactor performance are identified. The fundamental effects of the OC characteristics, the design parameters, and the operating conditions are studied. The design procedures are presented on the basis of the relative importance of each parameter, enabling a systematic methodology of selecting the design parameters and the operating conditions with different OCs. Part 2 presents the application of the methodology to the designs with the three commonly used OCs, i.e., nickel, copper, and iron, and compares the simulated performances of the designs. © 2013 Elsevier Ltd. All rights reserved.

  6. Current State of Agile Methodologies Worldwide and in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Martin Tománek

    2015-06-01

    Full Text Available The objective of this research paper is to compare the current state of agile methodologies in the world and in the Czech Republic. The comparison is executed as the comparative analysis of two publicly available researches conducted in 2013 and published in 2014. The comparison is further enriched by the results of the unpublished survey in the global logistics company which was conducted also in 2013. The potential trend for agile methodologies in the Czech Republic is also discussed with regard to the worldwide trend.

  7. A Model-Based Methodology for Simultaneous Design and Control of a Bioethanol Production Process

    DEFF Research Database (Denmark)

    Alvarado-Morales, Merlin; Abd.Hamid, Mohd-Kamaruddin; Sin, Gürkan

    2010-01-01

    In this work, a framework for the simultaneous solution of design and control problems is presented. Within this framework, two methodologies are presented, the integrated process design and controller design (IPDC) methodology and the process-group contribution (PGC) methodology. The concepts...... of attainable region (AR), driving force (DF), process-group (PG) and reverse simulation are used within these methodologies. The IPDC methodology is used to find the optimal design-control strategy of a process by locating the maximum point in the AR and DF diagrams for reactor and separator, respectively....... The PGC methodology is used to generate more efficient separation designs in terms of energy consumption by targeting the separation task at the largest DF. Both methodologies are highlighted through the application of two case studies, a bioethanol production process and a succinic acid production...

  8. Performance Driven Design and Design Information Exchange: Establishing a computational design methodology for parametric and performance-driven design of structures via topology optimization for rough structurally informed design models

    NARCIS (Netherlands)

    Mostafavi, S.; Morales Beltran, M.G.; Biloria, N.M.

    2013-01-01

    This paper presents a performance driven computational design methodology through introducing a case on parametric structural design. The paper describes the process of design technology development and frames a design methodology through which engineering, -in this case structural- aspects of

  9. Multidisciplinary design and optimization (MDO) methodology for the aircraft conceptual design

    Science.gov (United States)

    Iqbal, Liaquat Ullah

    An integrated design and optimization methodology has been developed for the conceptual design of an aircraft. The methodology brings higher fidelity Computer Aided Design, Engineering and Manufacturing (CAD, CAE and CAM) Tools such as CATIA, FLUENT, ANSYS and SURFCAM into the conceptual design by utilizing Excel as the integrator and controller. The approach is demonstrated to integrate with many of the existing low to medium fidelity codes such as the aerodynamic panel code called CMARC and sizing and constraint analysis codes, thus providing the multi-fidelity capabilities to the aircraft designer. The higher fidelity design information from the CAD and CAE tools for the geometry, aerodynamics, structural and environmental performance is provided for the application of the structured design methods such as the Quality Function Deployment (QFD) and the Pugh's Method. The higher fidelity tools bring the quantitative aspects of a design such as precise measurements of weight, volume, surface areas, center of gravity (CG) location, lift over drag ratio, and structural weight, as well as the qualitative aspects such as external geometry definition, internal layout, and coloring scheme early in the design process. The performance and safety risks involved with the new technologies can be reduced by modeling and assessing their impact more accurately on the performance of the aircraft. The methodology also enables the design and evaluation of the novel concepts such as the blended (BWB) and the hybrid wing body (HWB) concepts. Higher fidelity computational fluid dynamics (CFD) and finite element analysis (FEA) allow verification of the claims for the performance gains in aerodynamics and ascertain risks of structural failure due to different pressure distribution in the fuselage as compared with the tube and wing design. The higher fidelity aerodynamics and structural models can lead to better cost estimates that help reduce the financial risks as well. This helps in

  10. Biomarker-Guided Adaptive Trial Designs in Phase II and Phase III: A Methodological Review.

    Directory of Open Access Journals (Sweden)

    Miranta Antoniou

    Full Text Available Personalized medicine is a growing area of research which aims to tailor the treatment given to a patient according to one or more personal characteristics. These characteristics can be demographic such as age or gender, or biological such as a genetic or other biomarker. Prior to utilizing a patient's biomarker information in clinical practice, robust testing in terms of analytical validity, clinical validity and clinical utility is necessary. A number of clinical trial designs have been proposed for testing a biomarker's clinical utility, including Phase II and Phase III clinical trials which aim to test the effectiveness of a biomarker-guided approach to treatment; these designs can be broadly classified into adaptive and non-adaptive. While adaptive designs allow planned modifications based on accumulating information during a trial, non-adaptive designs are typically simpler but less flexible.We have undertaken a comprehensive review of biomarker-guided adaptive trial designs proposed in the past decade. We have identified eight distinct biomarker-guided adaptive designs and nine variations from 107 studies. Substantial variability has been observed in terms of how trial designs are described and particularly in the terminology used by different authors. We have graphically displayed the current biomarker-guided adaptive trial designs and summarised the characteristics of each design.Our in-depth overview provides future researchers with clarity in definition, methodology and terminology for biomarker-guided adaptive trial designs.

  11. A Synergy between the Technological Process and a Methodology for Web Design: Implications for Technological Problem Solving and Design

    Science.gov (United States)

    Jakovljevic, Maria; Ankiewicz, Piet; De swardt, Estelle; Gross, Elna

    2004-01-01

    Traditional instructional methodology in the Information System Design (ISD) environment lacks explicit strategies for promoting the cognitive skills of prospective system designers. This contributes to the fragmented knowledge and low motivational and creative involvement of learners in system design tasks. In addition, present ISD methodologies,…

  12. Progressive design methodology for complex engineering systems based on multiobjective genetic algorithms and linguistic decision making

    NARCIS (Netherlands)

    Kumar, P.; Bauer, P.

    2008-01-01

    This work focuses on a design methodology that aids in design and development of complex engineering systems. This design methodology consists of simulation, optimization and decision making. Within this work a framework is presented in which modelling, multi-objective optimization and multi

  13. Progressive design methodology for complex engineering systems based on multiobjective genetic algorithms and linguistic decision making

    NARCIS (Netherlands)

    Kumar, P.; Bauer, P.

    2008-01-01

    This work focuses on a design methodology that aids in design and development of complex engineering systems. This design methodology consists of simulation, optimization and decision making. Within this work a framework is presented in which modelling, multi-objective optimization and multi criteri

  14. Methodological background and design tools in the architectural design of the biomimetic envelope

    Directory of Open Access Journals (Sweden)

    Adriana Edith Granero

    2013-12-01

    Full Text Available This research responds to the problem of sustainable architectural design, with a search in the background and tools that support the concept of an architectural shell, with a building system inspired by bio-mimicry and organizing an architectural limit from a structure cell, as a proposal that challenges the improvement of models, is seeking balance between design and use of resources. The objective is to get an analysis of methodological background and design tools to create an architectural shell, inspired by bio-mimicry and to reduce energy consumption of a building designed for the climate of Buenos Aires, Argentina, with passive design and to respond to effects of insolation and illumination.

  15. Diversified Approaches and Current Trends of Syllabus Design

    Institute of Scientific and Technical Information of China (English)

    靳亦诗

    2015-01-01

    <正>1.What is Syllabus Design According Nunan(2004),syllabus design is essentially concerned with the selection and grading of content,methodology with selecting and sequencing appropriate learning experience and evaluation with appraising learners and determining of the curriculum as a whole.Thus syllabus design has vital importance for the implication of the curriculum.

  16. A Visual Analytics Based Decision Support Methodology For Evaluating Low Energy Building Design Alternatives

    Science.gov (United States)

    Dutta, Ranojoy

    The ability to design high performance buildings has acquired great importance in recent years due to numerous federal, societal and environmental initiatives. However, this endeavor is much more demanding in terms of designer expertise and time. It requires a whole new level of synergy between automated performance prediction with the human capabilities to perceive, evaluate and ultimately select a suitable solution. While performance prediction can be highly automated through the use of computers, performance evaluation cannot, unless it is with respect to a single criterion. The need to address multi-criteria requirements makes it more valuable for a designer to know the "latitude" or "degrees of freedom" he has in changing certain design variables while achieving preset criteria such as energy performance, life cycle cost, environmental impacts etc. This requirement can be met by a decision support framework based on near-optimal "satisficing" as opposed to purely optimal decision making techniques. Currently, such a comprehensive design framework is lacking, which is the basis for undertaking this research. The primary objective of this research is to facilitate a complementary relationship between designers and computers for Multi-Criterion Decision Making (MCDM) during high performance building design. It is based on the application of Monte Carlo approaches to create a database of solutions using deterministic whole building energy simulations, along with data mining methods to rank variable importance and reduce the multi-dimensionality of the problem. A novel interactive visualization approach is then proposed which uses regression based models to create dynamic interplays of how varying these important variables affect the multiple criteria, while providing a visual range or band of variation of the different design parameters. The MCDM process has been incorporated into an alternative methodology for high performance building design referred to as

  17. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect

    DEFF Research Database (Denmark)

    Triantafyllou, Evangelia; Kofoed, Lise; Purwins, Hendrik

    2016-01-01

    , while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators......One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class...... through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM) are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens...

  18. A performance-oriented power transformer design methodology using multi-objective evolutionary optimization

    Directory of Open Access Journals (Sweden)

    Amr A. Adly

    2015-05-01

    Full Text Available Transformers are regarded as crucial components in power systems. Due to market globalization, power transformer manufacturers are facing an increasingly competitive environment that mandates the adoption of design strategies yielding better performance at lower costs. In this paper, a power transformer design methodology using multi-objective evolutionary optimization is proposed. Using this methodology, which is tailored to be target performance design-oriented, quick rough estimation of transformer design specifics may be inferred. Testing of the suggested approach revealed significant qualitative and quantitative match with measured design and performance values. Details of the proposed methodology as well as sample design results are reported in the paper.

  19. A performance-oriented power transformer design methodology using multi-objective evolutionary optimization.

    Science.gov (United States)

    Adly, Amr A; Abd-El-Hafiz, Salwa K

    2015-05-01

    Transformers are regarded as crucial components in power systems. Due to market globalization, power transformer manufacturers are facing an increasingly competitive environment that mandates the adoption of design strategies yielding better performance at lower costs. In this paper, a power transformer design methodology using multi-objective evolutionary optimization is proposed. Using this methodology, which is tailored to be target performance design-oriented, quick rough estimation of transformer design specifics may be inferred. Testing of the suggested approach revealed significant qualitative and quantitative match with measured design and performance values. Details of the proposed methodology as well as sample design results are reported in the paper.

  20. Community-wide assessment of protein-interface modeling suggests improvements to design methodology.

    Science.gov (United States)

    Fleishman, Sarel J; Whitehead, Timothy A; Strauch, Eva-Maria; Corn, Jacob E; Qin, Sanbo; Zhou, Huan-Xiang; Mitchell, Julie C; Demerdash, Omar N A; Takeda-Shitaka, Mayuko; Terashi, Genki; Moal, Iain H; Li, Xiaofan; Bates, Paul A; Zacharias, Martin; Park, Hahnbeom; Ko, Jun-su; Lee, Hasup; Seok, Chaok; Bourquard, Thomas; Bernauer, Julie; Poupon, Anne; Azé, Jérôme; Soner, Seren; Ovali, Sefik Kerem; Ozbek, Pemra; Tal, Nir Ben; Haliloglu, Türkan; Hwang, Howook; Vreven, Thom; Pierce, Brian G; Weng, Zhiping; Pérez-Cano, Laura; Pons, Carles; Fernández-Recio, Juan; Jiang, Fan; Yang, Feng; Gong, Xinqi; Cao, Libin; Xu, Xianjin; Liu, Bin; Wang, Panwen; Li, Chunhua; Wang, Cunxin; Robert, Charles H; Guharoy, Mainak; Liu, Shiyong; Huang, Yangyu; Li, Lin; Guo, Dachuan; Chen, Ying; Xiao, Yi; London, Nir; Itzhaki, Zohar; Schueler-Furman, Ora; Inbar, Yuval; Potapov, Vladimir; Cohen, Mati; Schreiber, Gideon; Tsuchiya, Yuko; Kanamori, Eiji; Standley, Daron M; Nakamura, Haruki; Kinoshita, Kengo; Driggers, Camden M; Hall, Robert G; Morgan, Jessica L; Hsu, Victor L; Zhan, Jian; Yang, Yuedong; Zhou, Yaoqi; Kastritis, Panagiotis L; Bonvin, Alexandre M J J; Zhang, Weiyi; Camacho, Carlos J; Kilambi, Krishna P; Sircar, Aroop; Gray, Jeffrey J; Ohue, Masahito; Uchikoga, Nobuyuki; Matsuzaki, Yuri; Ishida, Takashi; Akiyama, Yutaka; Khashan, Raed; Bush, Stephen; Fouches, Denis; Tropsha, Alexander; Esquivel-Rodríguez, Juan; Kihara, Daisuke; Stranges, P Benjamin; Jacak, Ron; Kuhlman, Brian; Huang, Sheng-You; Zou, Xiaoqin; Wodak, Shoshana J; Janin, Joel; Baker, David

    2011-11-25

    The CAPRI (Critical Assessment of Predicted Interactions) and CASP (Critical Assessment of protein Structure Prediction) experiments have demonstrated the power of community-wide tests of methodology in assessing the current state of the art and spurring progress in the very challenging areas of protein docking and structure prediction. We sought to bring the power of community-wide experiments to bear on a very challenging protein design problem that provides a complementary but equally fundamental test of current understanding of protein-binding thermodynamics. We have generated a number of designed protein-protein interfaces with very favorable computed binding energies but which do not appear to be formed in experiments, suggesting that there may be important physical chemistry missing in the energy calculations. A total of 28 research groups took up the challenge of determining what is missing: we provided structures of 87 designed complexes and 120 naturally occurring complexes and asked participants to identify energetic contributions and/or structural features that distinguish between the two sets. The community found that electrostatics and solvation terms partially distinguish the designs from the natural complexes, largely due to the nonpolar character of the designed interactions. Beyond this polarity difference, the community found that the designed binding surfaces were, on average, structurally less embedded in the designed monomers, suggesting that backbone conformational rigidity at the designed surface is important for realization of the designed function. These results can be used to improve computational design strategies, but there is still much to be learned; for example, one designed complex, which does form in experiments, was classified by all metrics as a nonbinder.

  1. Design Methodology for Magnetic Field-Based Soft Tri-Axis Tactile Sensors.

    Science.gov (United States)

    Wang, Hongbo; de Boer, Greg; Kow, Junwai; Alazmani, Ali; Ghajari, Mazdak; Hewson, Robert; Culmer, Peter

    2016-08-24

    Tactile sensors are essential if robots are to safely interact with the external world and to dexterously manipulate objects. Current tactile sensors have limitations restricting their use, notably being too fragile or having limited performance. Magnetic field-based soft tactile sensors offer a potential improvement, being durable, low cost, accurate and high bandwidth, but they are relatively undeveloped because of the complexities involved in design and calibration. This paper presents a general design methodology for magnetic field-based three-axis soft tactile sensors, enabling researchers to easily develop specific tactile sensors for a variety of applications. All aspects (design, fabrication, calibration and evaluation) of the development of tri-axis soft tactile sensors are presented and discussed. A moving least square approach is used to decouple and convert the magnetic field signal to force output to eliminate non-linearity and cross-talk effects. A case study of a tactile sensor prototype, MagOne, was developed. This achieved a resolution of 1.42 mN in normal force measurement (0.71 mN in shear force), good output repeatability and has a maximum hysteresis error of 3.4%. These results outperform comparable sensors reported previously, highlighting the efficacy of our methodology for sensor design.

  2. Design Methodology for Magnetic Field-Based Soft Tri-Axis Tactile Sensors

    Directory of Open Access Journals (Sweden)

    Hongbo Wang

    2016-08-01

    Full Text Available Tactile sensors are essential if robots are to safely interact with the external world and to dexterously manipulate objects. Current tactile sensors have limitations restricting their use, notably being too fragile or having limited performance. Magnetic field-based soft tactile sensors offer a potential improvement, being durable, low cost, accurate and high bandwidth, but they are relatively undeveloped because of the complexities involved in design and calibration. This paper presents a general design methodology for magnetic field-based three-axis soft tactile sensors, enabling researchers to easily develop specific tactile sensors for a variety of applications. All aspects (design, fabrication, calibration and evaluation of the development of tri-axis soft tactile sensors are presented and discussed. A moving least square approach is used to decouple and convert the magnetic field signal to force output to eliminate non-linearity and cross-talk effects. A case study of a tactile sensor prototype, MagOne, was developed. This achieved a resolution of 1.42 mN in normal force measurement (0.71 mN in shear force, good output repeatability and has a maximum hysteresis error of 3.4%. These results outperform comparable sensors reported previously, highlighting the efficacy of our methodology for sensor design.

  3. Design Methodology for Magnetic Field-Based Soft Tri-Axis Tactile Sensors

    Science.gov (United States)

    Wang, Hongbo; de Boer, Greg; Kow, Junwai; Alazmani, Ali; Ghajari, Mazdak; Hewson, Robert; Culmer, Peter

    2016-01-01

    Tactile sensors are essential if robots are to safely interact with the external world and to dexterously manipulate objects. Current tactile sensors have limitations restricting their use, notably being too fragile or having limited performance. Magnetic field-based soft tactile sensors offer a potential improvement, being durable, low cost, accurate and high bandwidth, but they are relatively undeveloped because of the complexities involved in design and calibration. This paper presents a general design methodology for magnetic field-based three-axis soft tactile sensors, enabling researchers to easily develop specific tactile sensors for a variety of applications. All aspects (design, fabrication, calibration and evaluation) of the development of tri-axis soft tactile sensors are presented and discussed. A moving least square approach is used to decouple and convert the magnetic field signal to force output to eliminate non-linearity and cross-talk effects. A case study of a tactile sensor prototype, MagOne, was developed. This achieved a resolution of 1.42 mN in normal force measurement (0.71 mN in shear force), good output repeatability and has a maximum hysteresis error of 3.4%. These results outperform comparable sensors reported previously, highlighting the efficacy of our methodology for sensor design. PMID:27563908

  4. Low-Radiation Cellular Inductive Powering of Rodent Wireless Brain Interfaces: Methodology and Design Guide.

    Science.gov (United States)

    Soltani, Nima; Aliroteh, Miaad S; Salam, M Tariqus; Perez Velazquez, Jose Luis; Genov, Roman

    2016-08-01

    This paper presents a general methodology of inductive power delivery in wireless chronic rodent electrophysiology applications. The focus is on such systems design considerations under the following key constraints: maximum power delivery under the allowable specific absorption rate (SAR), low cost and spatial scalability. The methodology includes inductive coil design considerations within a low-frequency ferrite-core-free power transfer link which includes a scalable coil-array power transmitter floor and a single-coil implanted or worn power receiver. A specific design example is presented that includes the concept of low-SAR cellular single-transmitter-coil powering through dynamic tracking of a magnet-less receiver spatial location. The transmitter coil instantaneous supply current is monitored using a small number of low-cost electronic components. A drop in its value indicates the proximity of the receiver due to the reflected impedance of the latter. Only the transmitter coil nearest to the receiver is activated. Operating at the low frequency of 1.5 MHz, the inductive powering floor delivers a maximum of 15.9 W below the IEEE C95 SAR limit, which is over three times greater than that in other recently reported designs. The power transfer efficiency of 39% and 13% at the nominal and maximum distances of 8 cm and 11 cm, respectively, is maintained.

  5. On-chip high-voltage generator design design methodology for charge pumps

    CERN Document Server

    Tanzawa, Toru

    2016-01-01

    This book provides various design techniques for switched-capacitor on-chip high-voltage generators, including charge pump circuits, regulators, level shifters, references, and oscillators.  Readers will see these techniques applied to system design in order to address the challenge of how the on-chip high-voltage generator is designed for Flash memories, LCD drivers, and other semiconductor devices to optimize the entire circuit area and power efficiency with a low voltage supply, while minimizing the cost.  This new edition includes a variety of useful updates, including coverage of power efficiency and comprehensive optimization methodologies for DC-DC voltage multipliers, modeling of extremely low voltage Dickson charge pumps, and modeling and optimum design of AC-DC switched-capacitor multipliers for energy harvesting and power transfer for RFID.

  6. Design methodology of the strength properties of medical knitted meshes

    Science.gov (United States)

    Mikołajczyk, Z.; Walkowska, A.

    2016-07-01

    One of the most important utility properties of medical knitted meshes intended for hernia and urological treatment is their bidirectional strength along the courses and wales. The value of this parameter, expected by the manufacturers and surgeons, is estimated at 100 N per 5 cm of the sample width. The most frequently, these meshes are produced on the basis of single- or double-guide stitches. They are made of polypropylene and polyester monofilament yarns with the diameter in the range from 0.6 to 1.2 mm, characterized by a high medical purity. The aim of the study was to develop the design methodology of meshes strength based on the geometrical construction of the stitch and strength of yarn. In the environment of the ProCAD warpknit 5 software the simulated stretching process of meshes together with an analysis of their geometry changes was carried out. Simulations were made for four selected representative stitches. Both on a built, unique measuring position and on the tensile testing machine the real parameters of the loops geometry of meshes were measured. Model of mechanical stretching of warp-knitted meshes along the courses and wales was developed. The thesis argument was made, that the force that breaks the loop of warp-knitted fabric is the lowest value of breaking forces of loop link yarns or yarns that create straight sections of loop. This thesis was associate with the theory of strength that uses the “the weakest link concept”. Experimental verification of model was carried out for the basic structure of the single-guide mesh. It has been shown that the real, relative strength of the mesh related to one course is equal to the strength of the yarn breakage in a loop, while the strength along the wales is close to breaking strength of a single yarn. In relation to the specific construction of the medical mesh, based on the knowledge of the density of the loops structure, the a-jour mesh geometry and the yarns strength, it is possible, with high

  7. Design Intelligent Model base Online Tuning Methodology for Nonlinear System

    Directory of Open Access Journals (Sweden)

    Ali Roshanzamir

    2014-04-01

    Full Text Available In various dynamic parameters systems that need to be training on-line adaptive control methodology is used. In this paper fuzzy model-base adaptive methodology is used to tune the linear Proportional Integral Derivative (PID controller. The main objectives in any systems are; stability, robust and reliability. However PID controller is used in many applications but it has many challenges to control of continuum robot. To solve these problems nonlinear adaptive methodology based on model base fuzzy logic is used. This research is used to reduce or eliminate the PID controller problems based on model reference fuzzy logic theory to control of flexible robot manipulator system and testing of the quality of process control in the simulation environment of MATLAB/SIMULINK Simulator.

  8. AN APPROACH TO DESIGN ADVANCED STANDARD ENCRYPTION ALGORITHM USING HARDWARE / SOFTWARE CO-DESIGN METHODOLOGY

    Directory of Open Access Journals (Sweden)

    MEGHANA A. HASAMNIS

    2012-05-01

    Full Text Available An Advanced Standard Encryption Algorithm (AES is widely used in modern consumer electronicproducts for security. The IEEE 802.15.4 Low-Rate wireless sensor networks also use AES algorithm wherelow power consumption is the priority. To reduce the time taken for encryption of huge data, the algorithm hasto be implemented in hardware. To meet the requirement for low area the algorithm has to be implemented insoftware. Hence, a balance has to be achieved between hardware and software implementations in terms of areaand speed, so as to improve the overall performance of the system. Also with the co-design methodology totalthermal power dissipation is reduced. In this paper, 128 bit AES algorithm is implemented with hardware incombination with software using Altera NIOS II Processor platform. Altera’s Quartus II environment is used fordesign of the system. Cyclone II FPGA is used as a development platform. Software program is written in C language. NIOS II ntegrated Development Environment (IDE is used to integrate hardware and software together. By adopting hardware / software co-design methodology for implementation of AES, results show that a onsiderable improvement in speed can be achieved as compared to software only approach. Further, the significant reduction in area is achieved as compared to hardware only approach. By the approach of co-design an optimized design in terms of speed and area is achieved and also the thermal power dissipation is reduced

  9. Study on Design Methodology of Mass Customization Products

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Based on introduction characteristics and classific at ion of Mass Customization (MC), the paper expounds foundations and design me thods of MC. The foundations of MC production are standardization, seriation and normality of production, guiding thought of Concurrent Engineering (CE), ap plication of CAD/CAM technology and etc. And design methods of MC products are d esign for product family, modular design, parameterization CAD, variant design, design for manufacturing (DFM) and design by customers. ...

  10. An aspect-oriented methodology for designing secure applications

    NARCIS (Netherlands)

    Georg, Geri; Ray, Indrakshi; Anastasakis, Kyriakos; Bordbar, Behzad; Toahchoodee, Manachai; Houmb, Siv Hilde

    2009-01-01

    We propose a methodology, based on aspect-oriented modeling (AOM), for incorporating security mechanisms in an application. The functionality of the application is described using the primary model and the attacks are specified using aspects. The attack aspect is composed with the primary model to o

  11. An aspect-oriented methodology for designing secure applications

    NARCIS (Netherlands)

    Georg, Geri; Ray, Indrakshi; Anastasakis, Kyriakos; Bordbar, Behzad; Toahchoodee, Manachai; Houmb, S.H.

    2009-01-01

    We propose a methodology, based on aspect-oriented modeling (AOM), for incorporating security mechanisms in an application. The functionality of the application is described using the primary model and the attacks are specified using aspects. The attack aspect is composed with the primary model to o

  12. A framework for using simulation methodology in ergonomics interventions in design projects

    DEFF Research Database (Denmark)

    Broberg, Ole; Duarte, Francisco; Andersen, Simone Nyholm

    2014-01-01

    The aim of this paper is to outline a framework of simulation methodology in design processes from an ergonomics perspective......The aim of this paper is to outline a framework of simulation methodology in design processes from an ergonomics perspective...

  13. Methodology of Computer-Aided Design of Variable Guide Vanes of Aircraft Engines

    Science.gov (United States)

    Falaleev, Sergei V.; Melentjev, Vladimir S.; Gvozdev, Alexander S.

    2016-01-01

    The paper presents a methodology which helps to avoid a great amount of costly experimental research. This methodology includes thermo-gas dynamic design of an engine and its mounts, the profiling of compressor flow path and cascade design of guide vanes. Employing a method elaborated by Howell, we provide a theoretical solution to the task of…

  14. Shape and Topology Optimization Methodologies Used in Architectural Design

    DEFF Research Database (Denmark)

    Frier, Christian; Kirkegaard, Poul Henning; Christiansen, Karl

    2004-01-01

    Architects and engineers both employ iterative multi-stage design procedures, starting with initial conceptual design and progressing to more detailed final design. The conceptual design for an architect can be very abstract, with content that might be more poetic than geometric. On the other hand...

  15. Game Methodology for Design Methods and Tools Selection

    Science.gov (United States)

    Ahmad, Rafiq; Lahonde, Nathalie; Omhover, Jean-françois

    2014-01-01

    Design process optimisation and intelligence are the key words of today's scientific community. A proliferation of methods has made design a convoluted area. Designers are usually afraid of selecting one method/tool over another and even expert designers may not necessarily know which method is the best to use in which circumstances. This…

  16. Towards a methodology for integrated design of mechatronic servo systems

    OpenAIRE

    Roos, Fredrik

    2007-01-01

    Traditional methods for mechatronics design are often based on a sequential approach, where the mechanical structure is designed first, and then fitted with off-the-shelf electric motors, drive electronics, gearheads and sensors. Finally a control system is designed and optimized for the already existing physical system. Such a design method, that doesn’t consider aspects from a control point of view during the design of the physical system, is unlikely to result in a system with optimal cont...

  17. Virtual smile design systems: a current review.

    Science.gov (United States)

    Zimmermann, Moritz; Mehl, Albert

    2015-01-01

    In the age of digital dentistry, virtual treatment planning is becoming an increasingly important element of dental practice. Thanks to new technological advances in the computer- assisted design and computer-assisted manufacturing (CAD/CAM) of dental restorations, predictable interdisciplinary treatment using the backward planning approach appears useful and feasible. Today, a virtual smile design can be used as the basis for creating an esthetic virtual setup of the desired final result. The virtual setup, in turn, is used to plan further treatment steps in an interdisciplinary team approach, and communicate the results to the patient. The smile design concept and the esthetic analyses required for it are described in this article. We include not only a step-by-step description of the virtual smile design workflow, but also describe and compare the several available smile design options and systems. Subsequently, a brief discussion of the advantages and limitations of virtual smile design is followed by a section on different ways to integrate a two-dimensional (2D) smile design into the digital three-dimensional (3D) workflow. New technological developments are also described, such as the integration of smile designs in digital face scans, and 3D diagnostic follow-up using intraoral scanners.

  18. IoT-Based Information System for Healthcare Application: Design Methodology Approach

    Directory of Open Access Journals (Sweden)

    Damian Dziak

    2017-06-01

    Full Text Available Over the last few decades, life expectancy has increased significantly. However, elderly people who live on their own often need assistance due to mobility difficulties, symptoms of dementia or other health problems. In such cases, an autonomous supporting system may be helpful. This paper proposes the Internet of Things (IoT-based information system for indoor and outdoor use. Since the conducted survey of related works indicated a lack of methodological approaches to the design process, therefore a Design Methodology (DM, which approaches the design target from the perspective of the stakeholders, contracting authorities and potential users, is introduced. The implemented solution applies the three-axial accelerometer and magnetometer, Pedestrian Dead Reckoning (PDR, thresholding and the decision trees algorithm. Such an architecture enables the localization of a monitored person within four room-zones with accuracy; furthermore, it identifies falls and the activities of lying, standing, sitting and walking. Based on the identified activities, the system classifies current activities as normal, suspicious or dangerous, which is used to notify the healthcare staff about possible problems. The real-life scenarios validated the high robustness of the proposed solution. Moreover, the test results satisfied both stakeholders and future users and ensured further cooperation with the project.

  19. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect and design for learning

    Directory of Open Access Journals (Sweden)

    Evangelia Triantafyllou

    2016-05-01

    Full Text Available One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class, while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens of learning design can promote the use of theories and methods to evaluate its effect on the achievement of learning objectives, and that it may draw attention to the employment of methods to gather learner responses. Moreover, a learning design approach can enforce the detailed description of activities, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics and values of different stakeholders (i.e. institutions, educators, learners, and external agents, which influence the design and success of flipped classrooms. Moreover, it looks at the teaching cycle from a flipped instruction model perspective and adjusts it to cater for the reflection loops educators are involved when designing, implementing and re-designing a flipped classroom. Finally, it highlights the effect of learning design on the guidance

  20. Applying a learning design methodology in the flipped classroom approach – empowering teachers to reflect and design for learning

    Directory of Open Access Journals (Sweden)

    Evangelia Triantafyllou

    2016-05-01

    Full Text Available One of the recent developments in teaching that heavily relies on current technology is the “flipped classroom” approach. In a flipped classroom the traditional lecture and homework sessions are inverted. Students are provided with online material in order to gain necessary knowledge before class, while class time is devoted to clarifications and application of this knowledge. The hypothesis is that there could be deep and creative discussions when teacher and students physically meet. This paper discusses how the learning design methodology can be applied to represent, share and guide educators through flipped classroom designs. In order to discuss the opportunities arising by this approach, the different components of the Learning Design – Conceptual Map (LD-CM are presented and examined in the context of the flipped classroom. It is shown that viewing the flipped classroom through the lens of learning design can promote the use of theories and methods to evaluate its effect on the achievement of learning objectives, and that it may draw attention to the employment of methods to gather learner responses. Moreover, a learning design approach can enforce the detailed description of activities, tools and resources used in specific flipped classroom models, and it can make educators more aware of the decisions that have to be taken and people who have to be involved when designing a flipped classroom. By using the LD-CM, this paper also draws attention to the importance of characteristics and values of different stakeholders (i.e. institutions, educators, learners, and external agents, which influence the design and success of flipped classrooms. Moreover, it looks at the teaching cycle from a flipped instruction model perspective and adjusts it to cater for the reflection loops educators are involved when designing, implementing and re-designing a flipped classroom. Finally, it highlights the effect of learning design on the guidance

  1. A Consistent Design Methodology for Wireless Embedded Systems

    Directory of Open Access Journals (Sweden)

    Sauzon G

    2005-01-01

    Full Text Available Complexity demand of modern communication systems, particularly in the wireless domain, grows at an astounding rate, a rate so high that the available complexity and even worse the design productivity required to convert algorithms into silicon are left far behind. This effect is commonly referred to as the design productivity crisis or simply the design gap. Since the design gap is predicted to widen every year, it is of utmost importance to look closer at the design flow of such communication systems in order to find improvements. While various ideas for speeding up designs have been proposed, very few have found their path into existing EDA products. This paper presents requirements for such tools and shows how an open design environment offers a solution to integrate existing EDA tools, allowing for a consistent design flow, considerably speeding up design times.

  2. Shape and Topology Optimization Methodologies Used in Architectural Design

    DEFF Research Database (Denmark)

    Frier, Christian; Kirkegaard, Poul Henning; Christiansen, Karl

    2004-01-01

    the conceptual design for a structural engineer tends to be more concrete in nature, i.e. the choice between an arch and a suspension structure, between concrete and steel. Still, these differences tend to vanish in some of the most successful examples of integrated architectural and engineering design.......Architects and engineers both employ iterative multi-stage design procedures, starting with initial conceptual design and progressing to more detailed final design. The conceptual design for an architect can be very abstract, with content that might be more poetic than geometric. On the other hand...

  3. A Methodology of Persona-centric Service Design

    OpenAIRE

    Hosono, S.; Hasegawa, M.; Hara, T.; Shimomura, Y; Arai, T.

    2009-01-01

    In order to clarify the customer’s inclination and provide them with better services, the persona-scenario method has been accepted in Requirements Engineering. A CAD tool proposed in Service Engineering also adopts persona-scenario and focuses on denoting and visualizing the quality factors in service receivers. However, the process of service development with persona has not been fully discussed yet. This paper proposes a methodology to identify the boundary of a whole service s...

  4. User-inspired design methodology using Affordance Structure Matrix (ASM for construction projects

    Directory of Open Access Journals (Sweden)

    Maheswari J. Uma

    2017-01-01

    Full Text Available Traditionally, design phase of construction projects is often performed with incomplete and inaccurate user preferences. This is due to inefficiencies in the methodologies used for capturing the user requirements that can subsequently lead to inconsistencies and result in non-optimised end-result. Iterations and subsequent reworks due to such design inefficiencies is one of the major reasons for unsuccessful project delivery as they impact project performance measures such as time and cost among others. The existing design theories and practice are primarily based on functional requirements. Function-based design deals with design of artifact alone, which may yield favourable or unfavourable consequences with the design artifact. However, incorporating other interactions such as interactions between user & designer is necessary for optimised end-result. Hence, the objective of this research work is to devise a systematic design methodology considering all the three interactions among users, designers and artefacts for improved design efficiency. In this study, it has been attempted to apply the theory of affordances in a case project that involves the design of an offshore facility. A step-by-step methodology for developing Affordance Structure Matrix (ASM, which integrates House of Quality (HOQ and Design Structure Matrix (DSM, is proposed that can effectively capture the user requirements. HOQ is a popular quality management tool for capturing client requirements and DSM is a matrix-based tool that can capture the interdependency among the design entities. The proposed methodology utilises the strengths of both the tools, as DSM compliments HOQ in the process. In this methodology, different affordances such as AUA (Artifact-User-Affordance, AAA (Artifact-Artifact-Affordance and DDA (Designer-Designer-Affordance are captured systematically. Affordance is considered to be user-driven in this context that is in contrast to prevailing design

  5. Design methodology for optimal hardware implementation of wavelet transform domain algorithms

    Science.gov (United States)

    Johnson-Bey, Charles; Mickens, Lisa P.

    2005-05-01

    The work presented in this paper lays the foundation for the development of an end-to-end system design methodology for implementing wavelet domain image/video processing algorithms in hardware using Xilinx field programmable gate arrays (FPGAs). With the integration of the Xilinx System Generator toolbox, this methodology will allow algorithm developers to design and implement their code using the familiar MATLAB/Simulink development environment. By using this methodology, algorithm developers will not be required to become proficient in the intricacies of hardware design, thus reducing the design cycle and time-to-market.

  6. Proposed Methodology for Design of Carbon Fiber Reinforced Polymer Spike Anchors into Reinforced Concrete

    Energy Technology Data Exchange (ETDEWEB)

    MacFarlane, Eric Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-26

    The included methodology, calculations, and drawings support design of Carbon Fiber Reinforced Polymer (CFRP) spike anchors for securing U-wrap CFRP onto reinforced concrete Tbeams. This content pertains to an installation in one of Los Alamos National Laboratory’s facilities. The anchors are part of a seismic rehabilitation to the subject facility. The information contained here is for information purposes only. The reader is encouraged to verify all equations, details, and methodology prior to usage in future projects. However, development of the content contained here complied with Los Alamos National Laboratory’s NQA-1 quality assurance program for nuclear structures. Furthermore, the formulations and details came from the referenced published literature. This literature represents the current state of the art for FRP anchor design. Construction personnel tested the subject anchor design to the required demand level demonstrated in the calculation. The testing demonstrated the ability of the anchors noted to carry loads in excess of 15 kips in direct tension. The anchors were not tested to failure in part because of the hazards associated with testing large-capacity tensile systems to failure. The calculation, methodology, and drawing originator was Eric MacFarlane of Los Alamos National Laboratory’s (LANL) Office of Seismic Hazards and Risk Mitigation (OSHRM). The checker for all components was Mike Salmon of the LANL OSHRM. The independent reviewers of all components were Insung Kim and Loring Wyllie of Degenkolb Engineers. Note that Insung Kim contributed to the initial formulations in the calculations that pertained directly to his Doctoral research.

  7. Ethics of Engagement: User-Centered Design and Rhetorical Methodology.

    Science.gov (United States)

    Salvo, Michael J.

    2001-01-01

    Explores the shift from observation of users to participation with users, describing and investigating three examples of user-centered design practice in order to consider the new ethical demands being made of technical communicators. Explores Pelle Ehn's participatory design method, Roger Whitehouse's design of tactile signage for blind users,…

  8. Developing an Interactive Augmented Prototyping Methodology to Support Design Reviews

    NARCIS (Netherlands)

    Verlinden, J.C.

    2014-01-01

    Physical prototypes and scale models play an important role in engineering design processes, especially in the field of industrial design. Such models are typically used to explore and discuss design concepts in various stages, from initial idea generation to manufacturing. Over the last decade, au

  9. Developing an Interactive Augmented Prototyping Methodology to Support Design Reviews

    NARCIS (Netherlands)

    Verlinden, J.C.

    2014-01-01

    Physical prototypes and scale models play an important role in engineering design processes, especially in the field of industrial design. Such models are typically used to explore and discuss design concepts in various stages, from initial idea generation to manufacturing. Over the last decade, au

  10. Sustainable Chemical Processes and Products. New Design Methodology and Design Tools

    OpenAIRE

    Korevaar, G.

    2004-01-01

    The current chemical industry is not sustainable, which leads to the fact that innovation of chemical processes and products is too often hazardous for society in general and the environment in particular. It really is a challenge to implement sustainability considerations in the design activities of chemical engineers. Therefore, the main question of this thesis is: how can a trained chemical engineer develop a conceptual design of a chemical process or a chemical product in such a way that ...

  11. A Novel Methodology for Designing Radix-2n Serial-Serial Multipliers

    Directory of Open Access Journals (Sweden)

    Abdurazzag S. Almiladi

    2010-01-01

    Full Text Available Problem statement: The fast growth and increase in complexity of digital and image processing systems necessitate the migration from ad hoc design methods to methodological ones. Methodologies will certainly ease the trade off selection for those systems and shortens the design time. To increase those gained values and expand the searching space more appropriate methodologies need to be developed. Approach: A new methodology (table methodology to design radix-2n serial-serial multipliers was presented. Unlike other methodologies, the table methodology was used for the full design cycle, from the algorithm to the detailed fine control. Results: The methodology was used to identify the drawbacks in existing radix-2n serial-serial multipliers as well as deriving new efficient ones. Conclusion/Recommendations: To the author's knowledge this is the first time tables are used in this novel way in tackling the complete solution space of serial-serial multipliers. One important merit of the new methodology is that it made it clear that there is no need of parallel loading in serial-parallel architectures and hence they can be transferred to serial-serial ones and a as a consequence a huge saving of bus width, I/O pins, area and energy will be achieved.

  12. Optimal color design of psychological counseling room by design of experiments and response surface methodology.

    Science.gov (United States)

    Liu, Wenjuan; Ji, Jianlin; Chen, Hua; Ye, Chenyu

    2014-01-01

    Color is one of the most powerful aspects of a psychological counseling environment. Little scientific research has been conducted on color design and much of the existing literature is based on observational studies. Using design of experiments and response surface methodology, this paper proposes an optimal color design approach for transforming patients' perception into color elements. Six indices, pleasant-unpleasant, interesting-uninteresting, exciting-boring, relaxing-distressing, safe-fearful, and active-inactive, were used to assess patients' impression. A total of 75 patients participated, including 42 for Experiment 1 and 33 for Experiment 2. 27 representative color samples were designed in Experiment 1, and the color sample (L = 75, a = 0, b = -60) was the most preferred one. In Experiment 2, this color sample was set as the 'central point', and three color attributes were optimized to maximize the patients' satisfaction. The experimental results show that the proposed method can get the optimal solution for color design of a counseling room.

  13. Design Thinking: A Methodology towards Sustainable Problem Solving in Higher Education in South Africa

    Science.gov (United States)

    Munyai, Keneilwe

    2016-01-01

    This short paper explores the potential contribution of design thinking methodology to the education and training system in South Africa. Design thinking is slowly gaining traction in South Africa. Design Thinking is gaining traction in South Africa. There is offered by the Hasso Plattner Institute of Design Thinking at the University of Cape Town…

  14. Applying axiomatic design methodology in developing modified libertation products

    Directory of Open Access Journals (Sweden)

    Bibiana Margarita Vallejo Díaz

    2010-04-01

    Full Text Available Some conceptual elements regarding the axiomatic design method were applied to a specific case-study regarding developing modified liberation compressed product (CLM-UN, for use in the agricultural sector as pH regulating agent in solil. The study was orientated towards defining functional requeriments, design parameters and process variables for manufacturing the product. Independence and information were evaluated, supporting axiomatic design as an alternative for integral product and process design (as a rational and systemic exercise, facilitating producing products having the quality which future users expect from them.

  15. Analysis of selection methodologies for combinatorial library design.

    Science.gov (United States)

    Pascual, Rosalia; Borrell, José I; Teixidó, Jordi

    2003-01-01

    We have implemented and adapted in Pralins (Program for Rational Analysis of Libraries in silico), the most popular sparse (cherry picking) and full array (sublibrary) selection algorithms: hierarchical clustering, k-means clustering, Optimum Binning, Jarvis Patrick, Pral-SE (partitioning techniques) and MaxSum, MaxMin, MaxMin averaged, DN2, CTD (distance-based methods). We have validated the program with an already synthesized three-component combinatorial library of FXR partial agonists characterized by standard computational chemistry descriptors as case study. This has let us analyze the goodness of both the partitioning techniques for space division and all the selection methodologies with respect to representativity in terms of population and space coverage for different selection sizes. Within the chemical space analyzed, both hierarchical clustering and Optimum Binning division strategies are found to be the most advantageous reference space divisions to be used in the subsequent population and space coverage studies. Complete hierarchical clustering appears also to be the preferred selection methodology for both sparse and full array problems. The full array restriction fulfillment can easily be overcome by convenient optimization algorithms that allow optimal reagent selection preserving > 90% of the population coverage.

  16. Current Trends in Wireless Sensor Network Design

    OpenAIRE

    Neha Jain; Agrawal, Dharma P.

    2005-01-01

    The self-organizing nature of sensor networks, their autonomous operation and potential architectural alternatives make them suitable for different data-centric applications. Their wider acceptance seems to be rising on the horizon. In this article, we present an overview of the current state of the art in the field of wireless sensor networks. We also present various open research issues and provide an insight about the latest developments that need to be explored in greater depth that could...

  17. A prototype computerized synthesis methodology for generic space access vehicle (SAV) conceptual design

    Science.gov (United States)

    Huang, Xiao

    2006-04-01

    Today's and especially tomorrow's competitive launch vehicle design environment requires the development of a dedicated generic Space Access Vehicle (SAV) design methodology. A total of 115 industrial, research, and academic aircraft, helicopter, missile, and launch vehicle design synthesis methodologies have been evaluated. As the survey indicates, each synthesis methodology tends to focus on a specific flight vehicle configuration, thus precluding the key capability to systematically compare flight vehicle design alternatives. The aim of the research investigation is to provide decision-making bodies and the practicing engineer a design process and tool box for robust modeling and simulation of flight vehicles where the ultimate performance characteristics may hinge on numerical subtleties. This will enable the designer of a SAV for the first time to consistently compare different classes of SAV configurations on an impartial basis. This dissertation presents the development steps required towards a generic (configuration independent) hands-on flight vehicle conceptual design synthesis methodology. This process is developed such that it can be applied to any flight vehicle class if desired. In the present context, the methodology has been put into operation for the conceptual design of a tourist Space Access Vehicle. The case study illustrates elements of the design methodology & algorithm for the class of Horizontal Takeoff and Horizontal Landing (HTHL) SAVs. The HTHL SAV design application clearly outlines how the conceptual design process can be centrally organized, executed and documented with focus on design transparency, physical understanding and the capability to reproduce results. This approach offers the project lead and creative design team a management process and tool which iteratively refines the individual design logic chosen, leading to mature design methods and algorithms. As illustrated, the HTHL SAV hands-on design methodology offers growth

  18. Software Designing Methodology for ICT4D Domain

    DEFF Research Database (Denmark)

    Zewge, Amanuel; Dittrich, Yvonne; Bekele, Rahel

    2014-01-01

    ICT Interventions at agriculture information service provide rural farmer with the knowledge to improve their wellbeing. There are various technological and operational components that go into design of a software system particularly in ICT for development initiatives. We aimed to design method t...

  19. Participant Observation, Anthropology Methodology and Design Anthropology Research Inquiry

    Science.gov (United States)

    Gunn, Wendy; Løgstrup, Louise B.

    2014-01-01

    Within the design studio, and across multiple field sites, the authors compare involvement of research tools and materials during collaborative processes of designing. Their aim is to trace temporal dimensions (shifts/ movements) of where and when learning takes place along different sites of practice. They do so by combining participant…

  20. LWR design decision methodology: Phase II. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-01-01

    Techniques were identified to augment existing design process at the component and system level in order to optimize cost and safety between alternative system designs. The method was demonstrated using the Surry Low Pressure Injection System (LPIS). Three possible backfit options were analyzed for the Surry LPIS, assessing the safety level of each option and estimating the acquisition and installation costs for each. (DLC)

  1. Participatory Pattern Workshops: A Methodology for Open Learning Design Inquiry

    Science.gov (United States)

    Mor, Yishay; Warburton, Steven; Winters, Niall

    2012-01-01

    In order to promote pedagogically informed use of technology, educators need to develop an active, inquisitive, design-oriented mindset. Design Patterns have been demonstrated as powerful mediators of theory-praxis conversations yet widespread adoption by the practitioner community remains a challenge. Over several years, the authors and their…

  2. Participant Observation, Anthropology Methodology and Design Anthropology Research Inquiry

    Science.gov (United States)

    Gunn, Wendy; Løgstrup, Louise B.

    2014-01-01

    Within the design studio, and across multiple field sites, the authors compare involvement of research tools and materials during collaborative processes of designing. Their aim is to trace temporal dimensions (shifts/ movements) of where and when learning takes place along different sites of practice. They do so by combining participant…

  3. An Innovative Methodology of Product Design from Nature

    Institute of Scientific and Technical Information of China (English)

    Hui-I Wen; Shu-jun Zhang; Kevin Hapeshi; Xiao-feng Wang

    2008-01-01

    Nature is an information sourcebeok of behaviour, function, colour and shape which can inspire visual design and invention. Studying the form and functional characteristics of a natural object can provide inspiration for product design and help to improve the marketability of manufactured products. The inspiration can be triggered either by direct observation or captured by threo-dimensional (3D) digitising techniques to obtain superficial information (geometry and colour). An art designer often creates a concept in the form of a two-dimensional (2D) sketch while engineering methods lead to a point cloud in 3D. Each has its limitations in that the art designer commonly lacks the knowledge to build a final product from a 2D sketch and the engineering designer's 3D point clouds may not be very beautiful. We propose a method for Product Design from Nature (PDN),coupling aesthetic intent and geometrical characteristics, exploring the interactions between designers and nature's systems in PDN. We believe that this approach would considerably reduce the lead time and cost of product design from nature.

  4. Sustainable Chemical Processes and Products. New Design Methodology and Design Tools

    NARCIS (Netherlands)

    Korevaar, G.

    2004-01-01

    The current chemical industry is not sustainable, which leads to the fact that innovation of chemical processes and products is too often hazardous for society in general and the environment in particular. It really is a challenge to implement sustainability considerations in the design activities

  5. Sustainable Chemical Processes and Products. New Design Methodology and Design Tools

    NARCIS (Netherlands)

    Korevaar, G.

    2004-01-01

    The current chemical industry is not sustainable, which leads to the fact that innovation of chemical processes and products is too often hazardous for society in general and the environment in particular. It really is a challenge to implement sustainability considerations in the design activities o

  6. Mixed methods research in tobacco control with youth and young adults: A methodological review of current strategies.

    Science.gov (United States)

    Fryer, Craig S; Seaman, Elizabeth L; Clark, Rachael S; Plano Clark, Vicki L

    2017-01-01

    Tobacco use among young people is a complex and serious global dilemma that demands innovative and diverse research approaches. The purpose of this methodological review was to examine the current use of mixed methods research in tobacco control with youth and young adult populations and to develop practical recommendations for tobacco control researchers interested in this methodology. Using PubMed, we searched five peer-reviewed journals that publish tobacco control empirical literature for the use of mixed methods research to study young populations, age 12-25 years. Our team analyzed the features of each article in terms of tobacco control topic, population, youth engagement strategies, and several essential elements of mixed methods research. We identified 23 mixed methods studies published by authors from five different countries reported between 2004 and 2015. These 23 articles examined various topics that included tobacco use behavior, tobacco marketing and branding, and cessation among youth and young adults. The most common mixed methods approach was variations of the concurrent design in which the qualitative and quantitative strands were administered at the same time and given equal priority. This review documented several innovative applications of mixed methods research as well as challenges in the reporting of the complex research designs. The use of mixed methods research in tobacco control has great potential for advancing the understanding of complex behavioral and sociocultural issues for all groups, especially youth and young adults.

  7. Mixed methods research in tobacco control with youth and young adults: A methodological review of current strategies

    Science.gov (United States)

    Seaman, Elizabeth L.; Clark, Rachael S.; Plano Clark, Vicki L.

    2017-01-01

    Introduction Tobacco use among young people is a complex and serious global dilemma that demands innovative and diverse research approaches. The purpose of this methodological review was to examine the current use of mixed methods research in tobacco control with youth and young adult populations and to develop practical recommendations for tobacco control researchers interested in this methodology. Methods Using PubMed, we searched five peer-reviewed journals that publish tobacco control empirical literature for the use of mixed methods research to study young populations, age 12–25 years. Our team analyzed the features of each article in terms of tobacco control topic, population, youth engagement strategies, and several essential elements of mixed methods research. Results We identified 23 mixed methods studies published by authors from five different countries reported between 2004 and 2015. These 23 articles examined various topics that included tobacco use behavior, tobacco marketing and branding, and cessation among youth and young adults. The most common mixed methods approach was variations of the concurrent design in which the qualitative and quantitative strands were administered at the same time and given equal priority. This review documented several innovative applications of mixed methods research as well as challenges in the reporting of the complex research designs. Conclusions The use of mixed methods research in tobacco control has great potential for advancing the understanding of complex behavioral and sociocultural issues for all groups, especially youth and young adults. PMID:28841689

  8. Application of optimal design methodologies in clinical pharmacology experiments.

    Science.gov (United States)

    Ogungbenro, Kayode; Dokoumetzidis, Aristides; Aarons, Leon

    2009-01-01

    Pharmacokinetics and pharmacodynamics data are often analysed by mixed-effects modelling techniques (also known as population analysis), which has become a standard tool in the pharmaceutical industries for drug development. The last 10 years has witnessed considerable interest in the application of experimental design theories to population pharmacokinetic and pharmacodynamic experiments. Design of population pharmacokinetic experiments involves selection and a careful balance of a number of design factors. Optimal design theory uses prior information about the model and parameter estimates to optimize a function of the Fisher information matrix to obtain the best combination of the design factors. This paper provides a review of the different approaches that have been described in the literature for optimal design of population pharmacokinetic and pharmacodynamic experiments. It describes options that are available and highlights some of the issues that could be of concern as regards practical application. It also discusses areas of application of optimal design theories in clinical pharmacology experiments. It is expected that as the awareness about the benefits of this approach increases, more people will embrace it and ultimately will lead to more efficient population pharmacokinetic and pharmacodynamic experiments and can also help to reduce both cost and time during drug development.

  9. Ensuring VGI Credibility in Urban-Community Data Generation: A Methodological Research Design

    Directory of Open Access Journals (Sweden)

    Jamie O'Brien

    2016-06-01

    Full Text Available In this paper we outline the methodological development of current research into urban community formations based on combinations of qualitative (volunteered and quantitative (spatial analytical and geo-statistical data. We outline a research design that addresses problems of data quality relating to credibility in volunteered geographic information (VGI intended for Web-enabled participatory planning. Here we have drawn on a dual notion of credibility in VGI data, and propose a methodological workflow to address its criteria. We propose a ‘super-positional’ model of urban community formations, and report on the combination of quantitative and participatory methods employed to underpin its integration. The objective of this methodological phase of study is to enhance confidence in the quality of data for Web-enabled participatory planning. Our participatory method has been supported by rigorous quantification of area characteristics, including participant communities’ demographic and socio-economic contexts. This participatory method provided participants with a ready and accessible format for observing and mark-making, which allowed the investigators to iterate rapidly a system design based on participants’ responses to the workshop tasks. Participatory workshops have involved secondary school-age children in socio-economically contrasting areas of Liverpool (Merseyside, UK, which offers a test-bed for comparing communities’ formations in comparative contexts, while bringing an under-represented section of the population into a planning domain, whose experience may stem from public and non-motorised transport modalities. Data has been gathered through one-day participatory workshops, featuring questionnaire surveys, local site analysis, perception mapping and brief, textual descriptions. This innovative approach will support Web-based participation among stakeholding planners, who may benefit from well-structured, community

  10. Design of an Emulsion-based Personal Detergent through a Model-based Chemical Product Design Methodology

    DEFF Research Database (Denmark)

    Mattei, Michele; Hill, Michael; Kontogeorgis, Georgios;

    2013-01-01

    An extended systematic methodology for the design of emulsion-based Chemical products is presented. The methodology consists of a model-based framework involving seven sequential hierarchical steps: starting with the identification of the needs to be satisfied by the product and then adding one...

  11. Design of an Emulsion-based Personal Detergent through a Model-based Chemical Product Design Methodology

    DEFF Research Database (Denmark)

    Mattei, Michele; Hill, Michael; Kontogeorgis, Georgios

    2013-01-01

    An extended systematic methodology for the design of emulsion-based Chemical products is presented. The methodology consists of a model-based framework involving seven sequential hierarchical steps: starting with the identification of the needs to be satisfied by the product and then adding one-b...

  12. Theoretical and Methodological Perspectives on Designing Video Studies of Interaction

    Directory of Open Access Journals (Sweden)

    Anna-Lena Rostvall

    2005-12-01

    Full Text Available In this article the authors discuss the theoretical basis for the methodological decisions made during the course of a Swedish research project on interaction and learning. The purpose is to discuss how different theories are applied at separate levels of the study. The study is structured on three levels, with separate sets of research questions and theoretical concepts. The levels reflect a close-up description, a systematic analysis, and an interpretation of how teachers and students act and interact. The data consist of 12 hours of video-recorded and transcribed music lessons from high school and college. Through a multidisciplinary theoretical framework, the general understanding of teaching and learning in terms of interaction can be widened. The authors also present a software tool developed to facilitate the processes of transcription and analysis of the video data.

  13. Organic, bionics & blob design - conceptual and methodological clarification

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl

    2015-01-01

    and discussions. Organic, Bionics and Blob Design is an example of such a vague concept. Vague concepts create confusion when the concepts are used in academic texts and in course descriptions, which should be understandable across international research and by exchange students. This article discusses the Tripod......Industrial design is a young field of science that works together with many disciplines, borrows concepts and constructs metaphors for product characterization and phenomenon description. The meaning of the penetrative or constructed concepts is crystallized over time through academic writings......-paradigms". The citation marks indicate that this study looks at paradigms as practice fields rather than as research programs. The field for this study is set by a design engineer education with courses that cover the three design disciplines....

  14. Optimum design methodologies for pile foundations in London

    Directory of Open Access Journals (Sweden)

    Christos Letsios

    2014-12-01

    Full Text Available Given the importance of pile foundations in geotechnical engineering for supporting high-significance structures such as bridges, high-rise buildings, power plant stations, offshore platforms and museums, it becomes a necessity to find the best pile foundation design in terms of performance and economy. The number of piles required might exceed several hundreds or even thousands while the pile foundation cost might exceed 20% of the construction cost of the superstructure. In this work the problem of finding optimized designs of pile foundations is examined and is performed in accordance to two design code recommendations, namely Eurocode 7 and DIN 4014. The proposed structural optimization procedure is implemented in two real-world cases both located in London, UK in order to assess the efficiency of the proposed design formulation.

  15. Design New Robust Self Tuning Fuzzy Backstopping Methodology

    OpenAIRE

    Omid Avatefipour; Farzin Piltan; Mahmoud Reza Safaei Nasrabad; Ghasem Sahamijoo; Alireza Khalilian

    2014-01-01

    This research is focused on proposed Proportional-Integral (PI) like fuzzy adaptive backstopping fuzzy algorithms based on Proportional-Derivative (PD) fuzzy rule base with the adaptation laws derived in the Lyapunov sense. Adaptive SISO PI like fuzzy adaptive backstopping fuzzy method has two main objectives; the first objective is design a SISO fuzzy system to compensate for the model uncertainties of the system, and the second objective is focused on the design PI like fuzzy controller bas...

  16. Product Family Design Methodology Using Object-Oriented Approach

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The serious competition environment of global marke t requests the enterprise to change traditional product development strategy and a dopt new theory in order to meet diverse customer needs while maintaining near m ass production efficiency, which is the main philosophy of mass customization. P roduct family design is research focus at present and also is the core technolog y of DFMC (design for mass customization). Firstly, this paper explores the fund amental issues of product family, such as concepts o...

  17. Systematic screening methodology and energy efficient design of ionic liquid-based separation processes

    DEFF Research Database (Denmark)

    Kulajanpeng, Kusuma; Suriyapraphadilok, Uthaiporn; Gani, Rafiqul

    2016-01-01

    A systematic methodology for the screening of ionic liquids (ILs) as entrainers and for the design of ILs-based separation processes in various homogeneous binary azeotropic mixtures has been developed. The methodology focuses on the homogeneous binary aqueous azeotropic systems (for example, wat...

  18. Information System Design Methodology Based on PERT/CPM Networking and Optimization Techniques.

    Science.gov (United States)

    Bose, Anindya

    The dissertation attempts to demonstrate that the program evaluation and review technique (PERT)/Critical Path Method (CPM) or some modified version thereof can be developed into an information system design methodology. The methodology utilizes PERT/CPM which isolates the basic functional units of a system and sets them in a dynamic time/cost…

  19. Methodology series module 8: Designing questionnaires andclinical record forms

    Directory of Open Access Journals (Sweden)

    Maninder Singh Setia

    2017-01-01

    Full Text Available As researchers, we often collect data on a clinical record form or a questionnaire. It is an important part of study design. If the questionnaire is not well designed, the data collected will not be useful. In this section of the module, we have discussed some practical aspects of designing a questionnaire. It is useful to make a list of all the variables that will be assessed in the study before preparing the questionnaire. The researcher should review all the existing questionnaires. It may be efficient to use an existing standardized questionnaire or scale. Many of these scales are freely available and may be used with an appropriate reference. However, some may be under copyright protection and permissions may be required to use the same questionnaire. While designing their own questionnaire, researchers may use open- or close-ended questions. It is important to design the responses appropriately as the format of responses will influence the analysis. Sometimes, one can collect the same information in multiple ways - continuous or categorical response. Besides these, the researcher can also use visual analog scales or Likert's scale in the questionnaire. Some practical take-home points are: (1 Use specific language while framing the questions; (2 write detailed instructions in the questionnaire; (3 use mutually exclusive response categories; (4 use skip patterns; (5 avoid double-barreled questions; and (6 anchor the time period if required.

  20. Design, construction, and characterization methodologies for synthetic microbial consortia.

    Science.gov (United States)

    Bernstein, Hans C; Carlson, Ross P

    2014-01-01

    Engineered microbial consortia are of growing interest to a range of scientists including bioprocess engineers, systems biologists, and microbiologists because of their ability to simultaneously optimize multiple tasks, to test fundamental systems science, and to understand the microbial ecology of environments like chronic wounds. Metabolic engineering, synthetic biology, and microbial ecology provide a sound scientific basis for designing, building, and analyzing consortium-based microbial platforms.This chapter outlines strategies and protocols useful for (1) in silico network design, (2) experimental strain construction, (3) consortia culturing including biofilm growth methods, and (4) physiological characterization of consortia. The laboratory and computational methods given here may be adapted for synthesis and characterization of other engineered consortia designs.

  1. A Test Methodology for Determining Space-Readiness of Xilinx SRAM-Based FPGA Designs

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Heather M [Los Alamos National Laboratory; Graham, Paul S [Los Alamos National Laboratory; Morgan, Keith S [Los Alamos National Laboratory; Caffrey, Michael P [Los Alamos National Laboratory

    2008-01-01

    Using reconfigurable, static random-access memory (SRAM) based field-programmable gate arrays (FPGAs) for space-based computation has been an exciting area of research for the past decade. Since both the circuit and the circuit's state is stored in radiation-tolerant memory, both could be alterd by the harsh space radiation environment. Both the circuit and the circuit's state can be prote cted by triple-moduler redundancy (TMR), but applying TMR to FPGA user designs is often an error-prone process. Faulty application of TMR could cause the FPGA user circuit to output incorrect data. This paper will describe a three-tiered methodology for testing FPGA user designs for space-readiness. We will describe the standard approach to testing FPGA user designs using a particle accelerator, as well as two methods using fault injection and a modeling tool. While accelerator testing is the current 'gold standard' for pre-launch testing, we believe the use of fault injection and modeling tools allows for easy, cheap and uniform access for discovering errors early in the design process.

  2. Organic, bionics & blob design - conceptual and methodological clarification

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl

    2015-01-01

    and discussions. Organic, Bionics and Blob Design is an example of such a vague concept. Vague concepts create confusion when the concepts are used in academic texts and in course descriptions, which should be understandable across international research and by exchange students. This article discusses the Tripod...... approach as a possible method to clarify meaning and as an aid to students' development of a technical terminology. The concepts must be used in the same context, in this example the context is Natural Design, and represent different analytical angles on scientific issues. The three concepts of Organic...

  3. An Integrated Design and Verification Methodology for Reconfigurable Multimedia Systems

    CERN Document Server

    Borgatti, M; Rossi, U; Lambert, J -L; Moussa, I; Fummi, F; Pravadelli, G

    2011-01-01

    Recently a lot of multimedia applications are emerging on portable appliances. They require both the flexibility of upgradeable devices (traditionally software based) and a powerful computing engine (typically hardware). In this context, programmable HW and dynamic reconfiguration allow novel approaches to the migration of algorithms from SW to HW. Thus, in the frame of the Symbad project, we propose an industrial design flow for reconfigurable SoC's. The goal of Symbad consists of developing a system level design platform for hardware and software SoC systems including formal and semi-formal verification techniques.

  4. Modeling the Cloud: Methodology for Cloud Computing Strategy and Design

    Science.gov (United States)

    2011-05-17

    Opportunities 4How can you determine which, if any, cloud computing technologies and services are suitable for the company? 4How does cloud technology differ...with existing service types, in terms of functions and characteristics? 4How can cloud technology support current and new service or application

  5. Methodological Support for Service-oriented Design with ISDL

    NARCIS (Netherlands)

    Quartel, Dick; Dijkman, R.M.; van Sinderen, Marten J.

    Currently, service-oriented computing is mainly technology-driven. Most developments focus on the technology that enables enterprises to describe, publish and compose application services, and to communicate with applications of other enterprises according to their service descriptions. In this

  6. Design methodology of single-feed compact near-isotropic antenna design

    KAUST Repository

    Su, Zhen

    2017-06-07

    The abundance of mobile wireless devices is giving rise to a new paradigm known as Internet of Things. In this paradigm, wireless devices will be everywhere and communicating with each other. Since they will be oriented randomly in the environment, they should be able to communicate equally in all directions in order to have stable communication link. Hence, compact near isotropic antennas are required, which can enable orientation insensitive communication. In this paper, we propose a simple design methodology to design a compact near-isotropic wire antenna based on equal vector potentials. As a proof of concept, a quarter wavelength monopole antennas has been designed that is wrapped on a 3D-printed box keeping the vector potentials in three orthogonal different directions equal. By optimizing the dimension of the antenna arms, a nearly isotropic radiation pattern is thus achieved. The results show that the antenna has a maximum gain of 2.2dBi at 900 MHz with gain derivation of 9.4dB.

  7. New Methods in Design Education: The Systemic Methodology and the Use of Sketch in the Conceptual Design Stage

    Science.gov (United States)

    Westermeyer, Juan Carlos Briede; Ortuno, Bernabe Hernandis

    2011-01-01

    This study describes the application of a new product concurrent design methodologies in the context in the education of industrial design. The use of the sketch has been utilized many times as a tool of creative expression especially in the conceptual design stage, in an intuitive way and a little out of the context of the reality needs that the…

  8. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    NARCIS (Netherlands)

    Clark, G.; Kosoris, J.; Nguyen Hong, L.; Crul, M.

    2009-01-01

    The Design for Sustainability (D4S) concept outlines methodologies for making sustainable improvements (social, economic and environmental) to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includ

  9. Drag &Drop, Mixed-Methodology-based Lab-on-Chip Design Optimization Software Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall objective is to develop a ?mixed-methodology?, drag and drop, component library (fluidic-lego)-based, system design and optimization tool for complex...

  10. Design and Methodology of the Korean Early Psychosis Cohort Study

    Science.gov (United States)

    Kim, Sung-Wan; Lee, Bong Ju; Kim, Jung Jin; Yu, Je-Chun; Lee, Kyu Young; Won, Seung-Hee; Lee, Seung-Hwan; Kim, Seung-Hyun; Kang, Shi Hyun

    2017-01-01

    The present study details the rationale and methodology of the Korean Early Psychosis Cohort Study (KEPS), which is a clinical cohort investigation of first episode psychosis patients from a Korean population. The KEPS is a prospective naturalistic observational cohort study that follows the participants for at least 2 years. This study includes patients between 18 and 45 years of age who fulfill the criteria for one of schizophrenia spectrum and other psychotic disorders according to the diagnostic criteria of DSM-5. Early psychosis is defined as first episode patients who received antipsychotic treatment for fewer than 4 consecutive weeks after the onset of illness or stabilized patients in the early stages of the disorder whose duration of illness was less than 2 years from the initiation of antipsychotic treatment. The primary outcome measures are treatment response, remission, recovery, and relapse. Additionally, several laboratory tests are conducted and a variety of objective and subjective psychiatric measures assessing early life trauma, lifestyle pattern, and social and cognitive functioning are administered. This long-term prospective cohort study may contribute to the development of early intervention strategies and the improvement of long-term outcomes in patients with schizophrenia. PMID:28096881

  11. Kids in the city study: research design and methodology

    Directory of Open Access Journals (Sweden)

    Kaiwai Hector

    2011-07-01

    Full Text Available Abstract Background Physical activity is essential for optimal physical and psychological health but substantial declines in children's activity levels have occurred in New Zealand and internationally. Children's independent mobility (i.e., outdoor play and traveling to destinations unsupervised, an integral component of physical activity in childhood, has also declined radically in recent decades. Safety-conscious parenting practices, car reliance and auto-centric urban design have converged to produce children living increasingly sedentary lives. This research investigates how urban neighborhood environments can support or enable or restrict children's independent mobility, thereby influencing physical activity accumulation and participation in daily life. Methods/Design The study is located in six Auckland, New Zealand neighborhoods, diverse in terms of urban design attributes, particularly residential density. Participants comprise 160 children aged 9-11 years and their parents/caregivers. Objective measures (global positioning systems, accelerometers, geographical information systems, observational audits assessed children's independent mobility and physical activity, neighborhood infrastructure, and streetscape attributes. Parent and child neighborhood perceptions and experiences were assessed using qualitative research methods. Discussion This study is one of the first internationally to examine the association of specific urban design attributes with child independent mobility. Using robust, appropriate, and best practice objective measures, this study provides robust epidemiological information regarding the relationships between the built environment and health outcomes for this population.

  12. Design methodologies for reliability of SSL LED boards

    NARCIS (Netherlands)

    Jakovenko, J.; Formánek, J.; Perpiñà, X.; Jorda, X.; Vellvehi, M.; Werkhoven, R.J.; Husák, M.; Kunen, J.M.G.; Bancken, P.; Bolt, P.J.; Gasse, A.

    2013-01-01

    This work presents a comparison of various LED board technologies from thermal, mechanical and reliability point of view provided by an accurate 3-D modelling. LED boards are proposed as a possible technology replacement of FR4 LED boards used in 400 lumen retrofit SSL lamps. Presented design method

  13. Situated Research Design and Methodological Choices in Formative Program Evaluation

    Science.gov (United States)

    Supovitz, Jonathan

    2013-01-01

    Design-based implementation research offers the opportunity to rethink the relationships between intervention, research, and situation to better attune research and evaluation to the program development process. Using a heuristic called the intervention development curve, I describe the rough trajectory that programs typically follow as they…

  14. Computer-methodology for designing pest sampling and monitoring programs

    NARCIS (Netherlands)

    Werf, van der W.; Nyrop, J.P.; Binns, M.R.; Kovach, J.

    1999-01-01

    This paper evaluates two distinct enterprises: (1) an ongoing attempt to produce an introductory book plus accompanying software tools on sampling and monitoring in pest management; and (2) application of the modelling approaches discussed in that book to the design of monitoring methods for

  15. Robust optimization methodologies for water supply systems design

    Directory of Open Access Journals (Sweden)

    J. Marques

    2012-08-01

    Full Text Available Water supply systems (WSSs are vital infrastructures for the well-being of people today. To achieve good customer satisfaction the water supply service must always be able to meet people's needs, in terms of both quantity and quality. But unpredictable extreme conditions can cause severe damage to WSSs and lead to poorer levels of service or even to their failure. Operators dealing with a system's day-to-day operation know that events like burst water mains can compromise the functioning of all or part of a system. To increase a system's reliability, therefore, designs should take into account operating conditions other than normal ones. Recent approaches based on robust optimization can be used to solve optimization problems which involve uncertainty and can find designs which are able to cope with a range of operating conditions. This paper presents a robust optimization model for the optimal design of water supply systems operating under different circumstances. The model presented here uses a hydraulic simulator linked to an optimizer based on a simulated annealing heuristic. The results show that robustness can be included in several ways for varying levels reliability and that it leads to more reliable designs for only small cost increases.

  16. Serration Design Methodology for Wind Turbine Noise Reduction

    Science.gov (United States)

    Mathew, J.; Singh, A.; Madsen, J.; Arce León, C.

    2016-09-01

    Trailing edge serrations are today an established method to reduce the aeroacoustic noise from wind turbine blades. In this paper, a brief introduction to the aerodynamic and acoustic design procedure used at LM Wind Power is given. Early field tests on serrations, retrofitted to the turbine blades, gave preliminary indication of their noise reduction potential. However, a multitude of challenges stand in the way of any proof of concept and a viable commercial product. LM undertook a methodical test and validation procedure to understand the impact of design parameters on serration performance, and quantify the uncertainties associated with the proposed designs. Aerodynamic and acoustic validation tests were carried out in number of wind tunnel facilities. Models were written to predict the aerodynamic, acoustic and structural performance of the serrations. LM serration designs have evolved over the period of time to address constraints imposed by aero performance, structural reliability, manufacturing and installation. The latest LM serration offering was tested in the field on three different wind turbines. A consistent noise reduction in excess of 1.5 dB was achieved in the field for all three turbines.

  17. Situated Research Design and Methodological Choices in Formative Program Evaluation

    Science.gov (United States)

    Supovitz, Jonathan

    2013-01-01

    Design-based implementation research offers the opportunity to rethink the relationships between intervention, research, and situation to better attune research and evaluation to the program development process. Using a heuristic called the intervention development curve, I describe the rough trajectory that programs typically follow as they…

  18. Design Based Research Methodology for Teaching with Technology in English

    Science.gov (United States)

    Jetnikoff, Anita

    2015-01-01

    Design based research (DBR) is an appropriate method for small scale educational research projects involving collaboration between teachers, students and researchers. It is particularly useful in collaborative projects where an intervention is implemented and evaluated in a grounded context. The intervention can be technological, or a new program…

  19. Application of Decomposition Methodology to Solve Integrated Process Design and Controller Design Problems for Reactor-Separator-Recycle System

    DEFF Research Database (Denmark)

    Abd.Hamid, Mohd-Kamaruddin; Sin, Gürkan; Gani, Rafiqul

    2010-01-01

    This paper presents the integrated process design and controller design (IPDC) for a reactor-separator-recycle (RSR) system and evaluates a decomposition methodology to solve the IPDC problem. Accordingly, the IPDC problem is solved by decomposing it into four hierarchical stages: (i) pre-analysi...... to the solution of IPDC problems for RSR systems.......This paper presents the integrated process design and controller design (IPDC) for a reactor-separator-recycle (RSR) system and evaluates a decomposition methodology to solve the IPDC problem. Accordingly, the IPDC problem is solved by decomposing it into four hierarchical stages: (i) pre...... the design of a RSR system involving consecutive reactions, A B -> C and shown to provide effective solutions that satisfy design, control and cost criteria. The advantage of the proposed methodology is that it is systematic, makes use of thermodynamic-process knowledge and provides valuable insights...

  20. Designing with Space Syntax: A configurative approach to architectural layout, proposing a computational methodology

    NARCIS (Netherlands)

    Nourian, P.; Rezvani, S.; Sariyildiz, I.S.

    2013-01-01

    This paper introduces a design methodology and a toolkit developed as a parametric CAD program for configurative design of architectural plan layouts. Using this toolkit, designers can start plan layout process with sketching the way functional spaces need to connect to each other. A tool draws an i

  1. [Methodology for the development and update of practice guidelines: current state].

    Science.gov (United States)

    Barrera-Cruz, Antonio; Viniegra-Osorio, Arturo; Valenzuela-Flores, Adriana Abigail; Torres-Arreola, Laura Pilar; Dávila-Torres, Javier

    2016-01-01

    The current scenario of health services in Mexico reveals as a priority the implementation of strategies that allow us to better respond to the needs and expectations of individuals and society as a whole, through the provision of efficient and effective alternatives for the prevention, diagnosis and treatment of diseases. In this context, clinical practice guidelines constitute an element of management in the health care system, whose objective is to establish a national bechmark for encouraging clinical and management decision making, based on recommendations from the best available evidence, in order to contribute to the quality and effectiveness of health care. The purpose of this document is to show the methodology used for the development and updating of clinical practice guidelines that the Instituto Mexicano del Seguro Social has developed in line with the sectorial model in order to serve the user of these guidelines.

  2. A general methodology and applications for conduction-like flow-channel design.

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, Eric B.; Fiechtner, Gregory J.

    2004-02-01

    A novel design methodology is developed for creating conduction devices in which fields are piecewise uniform. This methodology allows the normally analytically intractable problem of Lagrangian transport to be solved using algebraic and trigonometric equations. Low-dispersion turns, manifolds, and expansions are developed. In this methodology, regions of piece-wise constant specific permeability (permeability per unit width) border each other with straight, generally tilted interfaces. The fields within each region are made uniform by satisfying a simple compatibility relation between the tilt angle and ratio of specific permeability of adjacent regions. This methodology has particular promise in the rational design of quasi-planar devices, in which the specific permeability is proportional to the depth of the channel. For such devices, the methodology can be implemented by connecting channel facets having two or more depths, fabricated, e.g., using a simple two-etch process.

  3. A successful methodology for designing and implementing virtual work teams

    Energy Technology Data Exchange (ETDEWEB)

    Stuewe, R.B.; Barnes, M.G.; Hughes, D.K.

    1997-11-01

    A system has been implemented at Los Alamos National Laboratory to rapidly staff and manage project teams. These project teams are created and subsequently perform their project functions using information technology as the communication medium. A simplified model of group interactions was used to guide the design and implementation of the system. The model uses three primary axes of group interactions to express the functional requirements that must be supported by a virtual work team application. The evolution of the approach and its relationship to traditional project management are described. A number of design characteristics were found to be critical to the success of the implementation and are presented. The technology and supporting processes and the business results stemming from implementation of the system are described in a limited manner.

  4. Aircraft systems design methodology and dispatch reliability prediction

    OpenAIRE

    Bineid, Mansour

    2005-01-01

    Aircraft despatch reliability was the main subject of this research in the wider content of aircraft reliability. The factors effecting dispatch reliability, aircraft delay, causes of aircraft delays, and aircraft delay costs and magnitudes were examined. Delay cost elements and aircraft delay scenarios were also studied. It concluded that aircraft dispatch reliability is affected by technical and non-technical factors, and that the former are under the designer's control. It showed that ...

  5. Aircraft systems design methodology and dispatch reliability prediction

    OpenAIRE

    Bineid, Mansour

    2005-01-01

    Aircraft despatch reliability was the main subject of this research in the wider content of aircraft reliability. The factors effecting dispatch reliability, aircraft delay, causes of aircraft delays, and aircraft delay costs and magnitudes were examined. Delay cost elements and aircraft delay scenarios were also studied. It concluded that aircraft dispatch reliability is affected by technical and non-technical factors, and that the former are under the designer's control. It showed that ...

  6. Using statistical design experiment methodologies to identify customers' needs

    OpenAIRE

    Huertas Garcia, Rubén; Consolación Segura, Carolina María

    2009-01-01

    Customer satisfaction has become one of the main objectives in all areas of business, especially the tourist trade. One of the most difficult problems is to know how to obtain this satisfaction, which involves identifying customers' needs and desires, and transferring them to our product or service specifications. In order to ascertain the consumer voice, we can ask consumers directly, or thy to deduce their requirements by indirect methods. Statistical design of experiments (SDE) is consider...

  7. Application of Decomposition Methodology to Solve Integrated Process Design and Controller Design Problems for Reactor-Separator-Recycle System

    DEFF Research Database (Denmark)

    Abd.Hamid, Mohd-Kamaruddin; Sin, Gürkan; Gani, Rafiqul

    2010-01-01

    This paper presents the integrated process design and controller design (IPDC) for a reactor-separator-recycle (RSR) system and evaluates a decomposition methodology to solve the IPDC problem. Accordingly, the IPDC problem is solved by decomposing it into four hierarchical stages: (i) pre...... the design of a RSR system involving consecutive reactions, A B -> C and shown to provide effective solutions that satisfy design, control and cost criteria. The advantage of the proposed methodology is that it is systematic, makes use of thermodynamic-process knowledge and provides valuable insights...

  8. Beyond (eco)design: current approaches to sustainable packaging design

    NARCIS (Netherlands)

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for marketi

  9. Beyond (eco)design: current approaches to sustainable packaging design

    NARCIS (Netherlands)

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for

  10. Design Methodology of Large-scale Thermoelectric Generation

    DEFF Research Database (Denmark)

    Chen, Min; Gao, Junling; Zhu, Junpeng

    2011-01-01

    -thermal-electric-circuit multiphysics behaviors. Firstly, a quasi one-dimension numerical model for the thermal fluids and their non-uniform temperature distribution as the boundary condition for TEMs is implemented in SPICE using electrothermal analogy. Secondly, the electric field calculation of the previously proposed device...... modeling and design scalable, flexible, and programmable. To validate the proposed system model, a TEGS including 8 TEMs is constructed. Through comparisons between simulation results and experimental data, it is clear that the cooptimization of the entire TEGS is enabled by the proposed model....

  11. Research Activities on Development of Piping Design Methodology of High Temperature Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Huh, Nam-Su [Seoul National Univ. of Science and Technology, Seoul(Korea, Republic of); Won, Min-Gu [Sungkyukwan Univ., Suwon (Korea, Republic of); Oh, Young-Jin [KEPCO Engineering and Construction Co. Inc., Gimcheon (Korea, Republic of); Lee, Hyeog-Yeon; Kim, Yoo-Gon [Korea Atomic Energy Research Institute, Daejeon(Korea, Republic of)

    2016-10-15

    A SFR is operated at high temperature and low pressure compared with commercial pressurized water reactor (PWR), and such an operating condition leads to time-dependent damages such as creep rupture, excessive creep deformation, creep-fatigue interaction and creep crack growth. Thus, high temperature design and structural integrity assessment methodology should be developed considering such failure mechanisms. In terms of design of mechanical components of SFR, ASME B and PV Code, Sec. III, Div. 5 and RCC-MRx provide high temperature design and assessment procedures for nuclear structural components operated at high temperature, and a Leak-Before-Break (LBB) assessment procedure for high temperature piping is also provided in RCC-MRx, A16. Three web-based evaluation programs based on the current high temperature codes were developed for structural components of high temperature reactors. Moreover, for the detailed LBB analyses of high temperature piping, new engineering methods for predicting creep C*-integral and creep COD rate based either on GE/EPRI or on reference stress concepts were proposed. Finally, the numerical methods based on Garofalo's model and RCC-MRx have been developed, and they have been implemented into ABAQUS. The predictions based on both models were compared with the experimental results, and it has been revealed that the predictions from Garafalo's model gave somewhat successful results to describe the deformation behavior of Gr. 91 at elevated temperatures.

  12. [Principles and methodology for ecological rehabilitation and security pattern design in key project construction].

    Science.gov (United States)

    Chen, Li-Ding; Lu, Yi-He; Tian, Hui-Ying; Shi, Qian

    2007-03-01

    Global ecological security becomes increasingly important with the intensive human activities. The function of ecological security is influenced by human activities, and in return, the efficiency of human activities will also be affected by the patterns of regional ecological security. Since the 1990s, China has initiated the construction of key projects "Yangtze Three Gorges Dam", "Qinghai-Tibet Railway", "West-to-East Gas Pipeline", "West-to-East Electricity Transmission" and "South-to-North Water Transfer" , etc. The interaction between these projects and regional ecological security has particularly attracted the attention of Chinese government. It is not only important for the regional environmental protection, but also of significance for the smoothly implementation of various projects aimed to develop an ecological rehabilitation system and to design a regional ecological security pattern. This paper made a systematic analysis on the types and characteristics of key project construction and their effects on the environment, and on the basis of this, brought forward the basic principles and methodology for ecological rehabilitation and security pattern design in this construction. It was considered that the following issues should be addressed in the implementation of a key project: 1) analysis and evaluation of current regional ecological environment, 2) evaluation of anthropogenic disturbances and their ecological risk, 3) regional ecological rehabilitation and security pattern design, 4) scenario analysis of environmental benefits of regional ecological security pattern, 5) re-optimization of regional ecological system framework, and 6) establishment of regional ecosystem management plan.

  13. Beyond (eco)design: current approaches to sustainable packaging design

    OpenAIRE

    Wever, R.

    2014-01-01

    Packaging has always received a lot of attention within the field of design for sustainability. The classical approach has been to mainly focus on reducing the impact of the packaging. This approach stems from the ill-informed position that packaging is superfluous, or at best there only for marketing reasons. This is a rather guild-based approach that, if taken to extremes, would lead to complete elimination of packaging, or at most a quintessential brown paper bag. In industry reality thoug...

  14. Friction and wear methodologies for design and control

    CERN Document Server

    Straffelini, Giovanni

    2015-01-01

    This book introduces the basic concepts of contact mechanics, friction, lubrication, and wear mechanisms, providing simplified analytical relationships that are useful for quantitative assessments. Subsequently, an overview on the main wear processes is provided, and guidelines on the most suitable design solutions for each specific application are outlined. The final part of the text is devoted to a description of the main materials and surface treatments specifically developed for tribological applications and to the presentation of tribological systems of particular engineering relevance. The text is up to date with the latest developments in the field of tribology and provides a theoretical framework to explain friction and wear problems, together with practical tools for their resolution. The text is intended for students on Engineering courses (both bachelor and master degrees) who must develop a sound understanding of friction, wear, lubrication, and surface engineering, and for technicians or professi...

  15. DESIGN NOTE: A very high output resistance current source

    Science.gov (United States)

    Hayatleh, K.; Terzopoulos, N.; Hart, B. L.

    2007-01-01

    The vertical stacking of two identical sub-circuits—improved versions of a bipolar transistor configuration proposed by Baxandall and Swallow—driven by dual output current mirrors, facilitates the design of a current generator producing a direct current of 1 mA with an incremental output resistance exceeding 200 GΩ.

  16. Performance Driven Design and Design Information Exchange: Establishing a computational design methodology for parametric and performance-driven design of structures via topology optimization for rough structurally informed design models

    NARCIS (Netherlands)

    Mostafavi, S.; Morales Beltran, M.G.; Biloria, N.M.

    2013-01-01

    This paper presents a performance driven computational design methodology through introducing a case on parametric structural design. The paper describes the process of design technology development and frames a design methodology through which engineering, -in this case structural- aspects of archi

  17. Thermo-mechanical Design Methodology for ITER Cryodistribution cold boxes

    Science.gov (United States)

    Shukla, Vinit; Patel, Pratik; Das, Jotirmoy; Vaghela, Hitensinh; Bhattacharya, Ritendra; Shah, Nitin; Choukekar, Ketan; Chang, Hyun-Sik; Sarkar, Biswanath

    2017-04-01

    The ITER cryo-distribution (CD) system is in charge of proper distribution of the cryogen at required mass flow rate, pressure and temperature level to the users; namely the superconducting (SC) magnets and cryopumps (CPs). The CD system is also capable to use the magnet structures as a thermal buffer in order to operate the cryo-plant as much as possible at a steady state condition. A typical CD cold box is equipped with mainly liquid helium (LHe) bath, heat exchangers (HX’s), cryogenic valves, filter, heaters, cold circulator, cold compressor and process piping. The various load combinations which are likely to occur during the life cycle of the CD cold boxes are imposed on the representative model and impacts on the system are analyzed. This study shows that break of insulation vacuum during nominal operation (NO) along with seismic event (Seismic Level-2) is the most stringent load combination having maximum stress of 224 MPa. However, NO+SMHV (Séismes Maximaux Historiquement Vraisemblables = Maximum Historically Probable Earthquakes) load combination is having the least safety margin and will lead the basis of the design of the CD system and its sub components. This paper presents and compares the results of different load combinations which are likely to occur on a typical CD cold box.

  18. Design-Based Research: Is This a Suitable Methodology for Short-Term Projects?

    Science.gov (United States)

    Pool, Jessica; Laubscher, Dorothy

    2016-01-01

    This article reports on a design-based methodology of a thesis in which a fully face-to-face contact module was converted into a blended learning course. The purpose of the article is to report on how design-based phases, in the form of micro-, meso- and macro-cycles were applied to improve practice and to generate design principles. Design-based…

  19. Design-Based Research: Is This a Suitable Methodology for Short-Term Projects?

    Science.gov (United States)

    Pool, Jessica; Laubscher, Dorothy

    2016-01-01

    This article reports on a design-based methodology of a thesis in which a fully face-to-face contact module was converted into a blended learning course. The purpose of the article is to report on how design-based phases, in the form of micro-, meso- and macro-cycles were applied to improve practice and to generate design principles. Design-based…

  20. Object-oriented analysis and design: a methodology for modeling the computer-based patient record.

    Science.gov (United States)

    Egyhazy, C J; Eyestone, S M; Martino, J; Hodgson, C L

    1998-08-01

    The article highlights the importance of an object-oriented analysis and design (OOAD) methodology for the computer-based patient record (CPR) in the military environment. Many OOAD methodologies do not adequately scale up, allow for efficient reuse of their products, or accommodate legacy systems. A methodology that addresses these issues is formulated and used to demonstrate its applicability in a large-scale health care service system. During a period of 6 months, a team of object modelers and domain experts formulated an OOAD methodology tailored to the Department of Defense Military Health System and used it to produce components of an object model for simple order processing. This methodology and the lessons learned during its implementation are described. This approach is necessary to achieve broad interoperability among heterogeneous automated information systems.

  1. Operational amplifier speed and accuracy improvement analog circuit design with structural methodology

    CERN Document Server

    Ivanov, Vadim V

    2004-01-01

    Operational Amplifier Speed and Accuracy Improvement proposes a new methodology for the design of analog integrated circuits. The usefulness of this methodology is demonstrated through the design of an operational amplifier. This methodology consists of the following iterative steps: description of the circuit functionality at a high level of abstraction using signal flow graphs; equivalent transformations and modifications of the graph to the form where all important parameters are controlled by dedicated feedback loops; and implementation of the structure using a library of elementary cells. Operational Amplifier Speed and Accuracy Improvement shows how to choose structures and design circuits which improve an operational amplifier's important parameters such as speed to power ratio, open loop gain, common-mode voltage rejection ratio, and power supply rejection ratio. The same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operat...

  2. Area-Efficient Selective Multi-Threshold CMOS Design Methodology for Standby Leakage Power Reduction

    CERN Document Server

    Kitahara, Takeshi; Minami, Fimihiro; Seta, Katsuhiro; Furusawa, Toshiyuki

    2011-01-01

    This paper presents a design flow for an improved selective multi-threshold(Selective-MT) circuit. The Selective-MT circuit is improved so that plural MT-cells can share one switch transistor. We propose the design methodology from RTL(Register Transfer Level) to final layout with optimizing switch transistor structure.

  3. Developing organ-on-a-chip concepts using bio-mechatronic design methodology.

    Science.gov (United States)

    Christoffersson, Jonas; van Noort, Danny; Mandenius, Carl-Fredrik

    2017-05-26

    Mechatronic design is an engineering methodology for conceiving, configuring and optimising the design of a technical device or product to the needs and requirements of the final user. In this article, we show how the basic principles of this methodology can be exploited for in vitro cell cultures-often referred to as organ-on-a-chip devices. Due to the key role of the biological cells, we have introduced the term bio-mechatronic design, to highlight the complexity of designing a system that should integrate biology, mechanics and electronics in the same device structure. The strength of the mechatronic design is to match the needs of the potential users to a systematic evaluation of overall functional design alternative. It may be especially attractive for organs-on-chips where biological constituents such as cells and tissues in 3D settings and in a fluidic environment should be compared, screened and selected. Through this approach, design solutions ranked to customer needs are generated according to specified criteria, thereby defining the key constraints of the fabrication. As an example, the bio-mechatronic methodology is applied to a liver-on-a-chip based on information extrapolated from previous theoretical and experimental knowledge. It is concluded that the methodology can generate new fabrication solutions for devices, as well as efficient guidelines for refining the design and fabrication of many of today's organ-on-a-chip devices.

  4. Development of a novel set of criteria to select methodology for designing product service systems

    Directory of Open Access Journals (Sweden)

    Tuananh Tran

    2016-04-01

    Full Text Available This paper proposes eight groups of twenty nine scoring criteria that can help designers and practitioners to compare and select an appropriate methodology for a certain problem in designing product service system (PSS. PSS has been researched for more than a decade and is now becoming more and more popular in academia as well as industry. Despite that fact, the adoption of PSS is still limited for its potential. One of the main reasons is that designing PSS itself is a challenge. Designers and developers face difficulties in choosing appropriate PSS design methodologies for their projects so that they can design effective PSS offerings. By proposing eight groups of twenty nine scoring criteria, this paper enables a “step by step” process to identify the most appropriate design methodology for a company’s PSS problem. An example is also introduced to illustrate the use of the proposed scoring criteria and provide a clear picture of how different design methodologies can be utilized at their best in terms of application.

  5. Designing food supply chains- a structured methodology: a case on novel protein foods

    NARCIS (Netherlands)

    Apaiah, R.K.

    2006-01-01

    This thesis proposes and implements a structured methodology to aid in chain design and the evaluation and decision making processes that accompany it.It focusesonhow to design the entire chain from start to finish, so that the

  6. A Step-by-Step Design Methodology for a Base Case Vanadium Redox-Flow Battery

    Science.gov (United States)

    Moore, Mark; Counce, Robert M.; Watson, Jack S.; Zawodzinski, Thomas A.; Kamath, Haresh

    2012-01-01

    The purpose of this work is to develop an evolutionary procedure to be used by Chemical Engineering students for the base-case design of a Vanadium Redox-Flow Battery. The design methodology is based on the work of Douglas (1985) and provides a profitability analysis at each decision level so that more profitable alternatives and directions can be…

  7. Developing a Design Methodology for Web 2.0 Mediated Learning

    DEFF Research Database (Denmark)

    2010-01-01

    Ed). We describe how this method has been adopted as part of a learning methodology building on concepts and models presented in the other symposium papers, in particular those of active, problem based learning and web 2.0-technologies. The challenge of designing on the basis of an explicit learning......In this paper we discuss the notion of a learning methodology and situate this within the wider frame of learning design or “Designing for Learning”. We discuss existing work within this broad area by trying to categorize different approaches and interpretations and we present our development...... of particular ‘mediating design artefacts’. We discuss what can be viewed as a lack of attention paid to integrating the preferred teaching styles and learning philosophies of practitioners into design tools, and present a particular method for learning design; the COllaborative E-learning Design method (Co...

  8. Developing a Design Methodology for Web 2.0 Mediated Learning

    DEFF Research Database (Denmark)

    2010-01-01

    In this paper we discuss the notion of a learning methodology and situate this within the wider frame of learning design or “Designing for Learning”. We discuss existing work within this broad area by trying to categorize different approaches and interpretations and we present our development...... of particular ‘mediating design artefacts’. We discuss what can be viewed as a lack of attention paid to integrating the preferred teaching styles and learning philosophies of practitioners into design tools, and present a particular method for learning design; the COllaborative E-learning Design method (Co......Ed). We describe how this method has been adopted as part of a learning methodology building on concepts and models presented in the other symposium papers, in particular those of active, problem based learning and web 2.0-technologies. The challenge of designing on the basis of an explicit learning...

  9. Developing a Design Methodology for Web 2.0 Mediated Learning

    DEFF Research Database (Denmark)

    Georgsen, Marianne; Buus, Lillian; Glud, Louise Nørgaard;

    2010-01-01

    of particular ‘mediating design artefacts’. We discuss what can be viewed as a lack of attention paid to integrating the preferred teaching styles and learning philosophies of practitioners into design tools, and present a particular method for learning design; the COllaborative E-learning Design method (Co......In this paper we discuss the notion of a learning methodology and situate this within the wider frame of learning design or “Designing for Learning”. We discuss existing work within this broad area by trying to categorize different approaches and interpretations and we present our development......Ed). We describe how this method has been adopted as part of a learning methodology building on concepts and models presented in the other symposium papers, in particular those of active, problem based learning and web 2.0-technologies. The challenge of designing on the basis of an explicit learning...

  10. The multi-copy simultaneous search methodology: a fundamental tool for structure-based drug design.

    Science.gov (United States)

    Schubert, Christian R; Stultz, Collin M

    2009-08-01

    Fragment-based ligand design approaches, such as the multi-copy simultaneous search (MCSS) methodology, have proven to be useful tools in the search for novel therapeutic compounds that bind pre-specified targets of known structure. MCSS offers a variety of advantages over more traditional high-throughput screening methods, and has been applied successfully to challenging targets. The methodology is quite general and can be used to construct functionality maps for proteins, DNA, and RNA. In this review, we describe the main aspects of the MCSS method and outline the general use of the methodology as a fundamental tool to guide the design of de novo lead compounds. We focus our discussion on the evaluation of MCSS results and the incorporation of protein flexibility into the methodology. In addition, we demonstrate on several specific examples how the information arising from the MCSS functionality maps has been successfully used to predict ligand binding to protein targets and RNA.

  11. Nonlinear Observer Design of the Generalized Rössler Hyperchaotic Systems via DIL Methodology

    Directory of Open Access Journals (Sweden)

    Yeong-Jeu Sun

    2012-01-01

    Full Text Available The generalized Rössler hyperchaotic systems are presented, and the state observation problem of such systems is investigated. Based on the differential inequality with Lyapunov methodology (DIL methodology, a nonlinear observer design for the generalized Rössler hyperchaotic systems is developed to guarantee the global exponential stability of the resulting error system. Meanwhile, the guaranteed exponential decay rate can be accurately estimated. Finally, numerical simulations are provided to illustrate the feasibility and effectiveness of proposed approach.

  12. Design methodology for bio-based processing: Biodiesel and fatty alcohol production

    DEFF Research Database (Denmark)

    Simasatikul, Lida; Arpornwichanop, Amornchai; Gani, Rafiqul

    2012-01-01

    A systematic design methodology is developed for producing two main products plus side products starting with one or more bio-based renewable source. A superstructure that includes all possible reaction and separation operations is generated through thermodynamic insights and available data. The ....... Economic analysis and net present value are determined to find the best economically and operationally feasible process. The application of the methodology is presented through a case study involving biodiesel and fatty alcohol productions....

  13. Design methodology for bio-based processing: Biodiesel and fatty alcohol production

    DEFF Research Database (Denmark)

    Simasatikul, Lida; Arpornwichanopa, Amornchai; Gani, Rafiqul

    2013-01-01

    A systematic design methodology is developed for producing multiple main products plus side products starting with one or more bio-based renewable source. A superstructure that includes all possible reaction and separation operations is generated through thermodynamic insights and available data........ Economic analysis and net present value are determined to find the best economically and operationally feasible process. The application of the methodology is presented through a case study involving biodiesel and fatty alcohol productions....

  14. The methodologies and instruments of vehicle particulate emission measurement for current and future legislative regulations

    Science.gov (United States)

    Otsuki, Yoshinori; Nakamura, Hiroshi; Arai, Masataka; Xu, Min

    2015-09-01

    Since the health risks associated with fine particles whose aerodynamic diameters are smaller than 2.5 μm was first proven, regulations restricting particulate matter (PM) mass emissions from internal combustion engines have become increasingly severe. Accordingly, the gravimetric method of PM mass measurement is facing its lower limit of detection as the emissions from vehicles are further reduced. For example, the variation in the adsorption of gaseous components such as hydrocarbons from unburned fuel and lubricant oil and the presence of agglomerated particles, which are not directly generated in engine combustion but re-entrainment particulates from walls of sampling pipes, can cause uncertainty in measurement. The PM mass measurement systems and methodologies have been continuously refined in order to improve measurement accuracy. As an alternative metric, the particle measurement programme (PMP) within the United Nations Economic Commission for Europe (UNECE) developed a solid particle number measurement method in order to improve the sensitivity of particulate emission measurement from vehicles. Consequently, particle number (PN) limits were implemented into the regulations in Europe from 2011. Recently, portable emission measurement systems (PEMS) for in-use vehicle emission measurements are also attracting attention, currently in North America and Europe, and real-time PM mass and PN instruments are under evaluation.

  15. Design and tolerance analysis of a low bending loss hole-assisted fiber using statistical design methodology.

    Science.gov (United States)

    Van Erps, Jürgen; Debaes, Christof; Nasilowski, Tomasz; Watté, Jan; Wojcik, Jan; Thienpont, Hugo

    2008-03-31

    We present the design of a low bending loss hole-assisted fiber for a 180?-bend fiber socket application, including a tolerance analysis for manufacturability. To this aim, we make use of statistical design methodology, combined with a fully vectorial mode solver. Two resulting designs are presented and their performance in terms of bending loss, coupling loss to Corning SMF-28 standard telecom fiber, and cut-off wavelength is calculated.

  16. DIMENSIONAL DESIGN THEORY AND METHODOLOGY OF 6-DOF SCISSOR PARALLEL MANIPULATOR

    Institute of Scientific and Technical Information of China (English)

    Tang Xiaoqiang; Li Tiemin; Wang Jinsong

    2004-01-01

    Parallel manipulators have many advantages over serial manipulators in terms of high load/weight ratio, velocity, stiffness and precision.A dimensional design theory and methodology of six degrees of freedom scissor parallel manipulator (SPM) is investigated.The SPM kinematics inverse equation is given.Based on the formulation of the local dexterity and the definition about the indexes of workspace incircle radius, the effects of the design parameters on the dexterity and workspace are discussed.Moreover the incircle radius change ratio about workspace are defined and used as the evaluated indicator to analyze the effects of the design parameters on the performances.A dimensional design theory that could satisfy the requirement of dexterity and workspace is proposed.The dimensional design theory and methodology can be of help in the design, trajectory planning and control of parallel manipulator.

  17. Co-design of RAD and ETHICS methodologies: a combination of information system development methods

    Science.gov (United States)

    Nasehi, Arezo; Shahriyari, Salman

    2011-12-01

    Co-design is a new trend in the social world which tries to capture different ideas in order to use the most appropriate features for a system. In this paper, co-design of two information system methodologies is regarded; rapid application development (RAD) and effective technical and human implementation of computer-based systems (ETHICS). We tried to consider the characteristics of these methodologies to see the possibility of having a co-design or combination of them for developing an information system. To reach this purpose, four different aspects of them are analyzed: social or technical approach, user participation and user involvement, job satisfaction, and overcoming change resistance. Finally, a case study using the quantitative method is analyzed in order to examine the possibility of co-design using these factors. The paper concludes that RAD and ETHICS are appropriate to be co-designed and brings some suggestions for the co-design.

  18. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    OpenAIRE

    Marcel Crul; Long Nguyen Hong; Garrette Clark; Justin Kosoris

    2009-01-01

    The Design for Sustainability (D4S) concept outlines methodologies for making sustainable improvements (social, economic and environmental) to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includes both incremental and radical innovation. The United Nations Environment Programme and the Delft University of Technology, the Netherlands, in concert with key partners, work to support, illustra...

  19. Adolescent Schizophrenia: A Methodologic Review of the Current Neuroimaging and Neuropsychologic Literature.

    Science.gov (United States)

    Findling, Robert L.; And Others

    1995-01-01

    This paper reviews the methodology in articles that have reported structural neuroimaging or neuropsychological data in adolescent patients with schizophrenia. Identification of methodological issues led to the finding that, at present, no conclusions can be made regarding the presence or absence of neuropsychologic dysfunction or structural…

  20. A Transformation-oriented Methodology to Knowledge-based Conceptual Data Warehouse Design

    Directory of Open Access Journals (Sweden)

    Opim S. Sitompul

    2006-01-01

    Full Text Available Applications of artificial intelligence (AI technology in the form of knowledge-based systems within the context of database design have been extensively researched particularly to provide support within the conceptual design phase. However, a similar approach to the task of data warehouse design has yet to be seriously initiated. In this paper, we proposed a design methodology for conceptual data warehouse design called the transformation-oriented methodology, which transforms an Entity-Relationship (ER model into a multidimensional model based on a series of transformation and analysis rules. The transformation-oriented methodology translates the ER model into a specification language model and transformed it into an initial problem domain model. A set of synthesis and diagnosis rules will then gradually transform the problem domain model into the multidimensional model. A prototype KB tool called the DWDesigner has been developed to implement the aforementioned methodology. The multidimensional model produces by the DWDesigner as output is presented in a graphical form for better visualization. Testing has been conducted to a number of design problems, such as university, business and hospital domains and consistent results have been achieved.

  1. Current psychometric and methodological issues in the measurement of overgeneral autobiographical memory.

    Science.gov (United States)

    Griffith, James W; Sumner, Jennifer A; Raes, Filip; Barnhofer, Thorsten; Debeer, Elise; Hermans, Dirk

    2012-12-01

    Autobiographical memory is a multifaceted construct that is related to psychopathology and other difficulties in functioning. Across many studies, a variety of methods have been used to study autobiographical memory. The relationship between overgeneral autobiographical memory (OGM) and psychopathology has been of particular interest, and many studies of this cognitive phenomenon rely on the Autobiographical Memory Test (AMT) to assess it. In this paper, we examine several methodological approaches to studying autobiographical memory, and focus primarily on methodological and psychometric considerations in OGM research. We pay particular attention to what is known about the reliability, validity, and methodological variations of the AMT. The AMT has adequate psychometric properties, but there is great variability in methodology across studies that use it. Methodological recommendations and suggestions for future studies are presented.

  2. The Health Behaviour in School-aged Children (HBSC) study: methodological developments and current tensions

    DEFF Research Database (Denmark)

    Roberts, C; Freeman, J; Samdal, O

    2009-01-01

    OBJECTIVES: To describe the methodological development of the HBSC survey since its inception and explore methodological tensions that need to be addressed in the ongoing work on this and other large-scale cross-national surveys. METHODS: Using archival data and conversations with members of the ...... in working through such challenges renders it likely that HBSC can provide a model of other similar studies facing these tensions.......OBJECTIVES: To describe the methodological development of the HBSC survey since its inception and explore methodological tensions that need to be addressed in the ongoing work on this and other large-scale cross-national surveys. METHODS: Using archival data and conversations with members...... of the network, we collaboratively analysed our joint understandings of the survey's methodology. RESULTS: We identified four tensions that are likely to be present in upcoming survey cycles: (1) maintaining quality standards against a background of rapid growth, (2) continuous improvement with limited financial...

  3. A systematic methodology for the design of continuous active pharmaceutical ingredient production processes

    DEFF Research Database (Denmark)

    Cervera Padrell, Albert Emili; Gani, Rafiqul; Kiil, Søren

    2011-01-01

    Continuous pharmaceutical manufacturing (CPM) has emerged as a powerful technology to obtain higher reaction yields and improved separation efficiencies, potentially leading to simplified process flowsheets, reduced total costs, lower environmental impacts, and safer and more flexible production...... and representation, as well as on how to employ this knowledge for process (re-)design. The aim of this paper is to introduce a methodology that systematically identifies already existing PSE methods and tools which can assist in the design of CPM processes. This methodology has been applied to a process...... for the production of an API developed by H. Lundbeck A/S, demonstrating the mentioned potential benefits that CPM can offer....

  4. An Exposition of Current Mobile Learning Design Guidelines and Frameworks

    Science.gov (United States)

    Teall, Ed; Wang, Minjuan; Callaghan, Vic; Ng, Jason W. P.

    2014-01-01

    As mobile devices with wireless access become more readily available, learning delivered via mobile devices of all types must be designed to ensure successful learning. This paper first examines three questions related to the design of mobile learning: 1) what mobile learning (m-learning) guidelines can be identified in the current literature, 2)…

  5. An Exposition of Current Mobile Learning Design Guidelines and Frameworks

    Science.gov (United States)

    Teall, Ed; Wang, Minjuan; Callaghan, Vic; Ng, Jason W. P.

    2014-01-01

    As mobile devices with wireless access become more readily available, learning delivered via mobile devices of all types must be designed to ensure successful learning. This paper first examines three questions related to the design of mobile learning: 1) what mobile learning (m-learning) guidelines can be identified in the current literature, 2)…

  6. A methodological approach to the design of optimising control strategies for sewer systems

    DEFF Research Database (Denmark)

    Mollerup, Ane Loft; Mikkelsen, Peter Steen; Sin, Gürkan

    2016-01-01

    This study focuses on designing an optimisation based control for sewer system in a methodological way and linking itto a regulatory control. Optimisation based design is found to depend on proper choice of a model, formulation of objective function and tuning of optimisation parameters. Accordin......This study focuses on designing an optimisation based control for sewer system in a methodological way and linking itto a regulatory control. Optimisation based design is found to depend on proper choice of a model, formulation of objective function and tuning of optimisation parameters...... control; a rule based expert system. On the other hand, compared with a regulatory control technique designed earlier in Mollerup et al. (2015), the optimisation showed similar performance with respect to minimising overflow volume. Hence for operation of small sewer systems, regulatory control strategies...... can offer promising potential and should be considered along more advanced strategies when identifying novel solutions....

  7. A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

    DEFF Research Database (Denmark)

    Lutze, Philip; Roman Martinez, Alicia; Woodley, John

    2012-01-01

    Process intensification (PI) has the potential to improve existing processes or create new process options, which are needed in order to produce products using more sustainable methods. In principle, an enormous number of process options can be generated but where and how the process should...... be intensified for the biggest improvement is difficult to identify. In this paper the development of a systematic computer aided model-based synthesis and design methodology incorporating PI is presented. In order to manage the complexities involved, the methodology employs a decomposition-based solution...... approach. Starting from an analysis of existing processes, the methodology generates a set of process options and reduces their number through several screening steps until from the remaining options, the optimal is found. The application of the methodology is highlighted through a case study involving...

  8. Logic design for array-based circuits a structured design methodology

    CERN Document Server

    White, D E

    1992-01-01

    This book will show you how to approach the design covering everything from the circuit specification to the final design acceptance, including what support you can expect, sizing, timing analysis, power and packaging, various simulations, design verification, and design submission.

  9. Methodology for object-oriented real-time systems analysis and design: Software engineering

    Science.gov (United States)

    Schoeffler, James D.

    1991-01-01

    Successful application of software engineering methodologies requires an integrated analysis and design life-cycle in which the various phases flow smoothly 'seamlessly' from analysis through design to implementation. Furthermore, different analysis methodologies often lead to different structuring of the system so that the transition from analysis to design may be awkward depending on the design methodology to be used. This is especially important when object-oriented programming is to be used for implementation when the original specification and perhaps high-level design is non-object oriented. Two approaches to real-time systems analysis which can lead to an object-oriented design are contrasted: (1) modeling the system using structured analysis with real-time extensions which emphasizes data and control flows followed by the abstraction of objects where the operations or methods of the objects correspond to processes in the data flow diagrams and then design in terms of these objects; and (2) modeling the system from the beginning as a set of naturally occurring concurrent entities (objects) each having its own time-behavior defined by a set of states and state-transition rules and seamlessly transforming the analysis models into high-level design models. A new concept of a 'real-time systems-analysis object' is introduced and becomes the basic building block of a series of seamlessly-connected models which progress from the object-oriented real-time systems analysis and design system analysis logical models through the physical architectural models and the high-level design stages. The methodology is appropriate to the overall specification including hardware and software modules. In software modules, the systems analysis objects are transformed into software objects.

  10. A Design Methodology for Folded, Pipelined Architectures in VLSI Applications using Projective Space Lattices

    CERN Document Server

    Sharma, Hrishikesh

    2011-01-01

    Semi-parallel, or folded, VLSI architectures are used whenever hardware resources need to be saved at design time. Most recent applications that are based on Projective Geometry (PG) based balanced bipartite graph also fall in this category. In this paper, we provide a high-level, top-down design methodology to design optimal semi-parallel architectures for applications, whose Data Flow Graph (DFG) is based on PG bipartite graph. Such applications have been found e.g. in error-control coding and matrix computations. Unlike many other folding schemes, the topology of connections between physical elements does not change in this methodology. Another advantage is the ease of implementation. To lessen the throughput loss due to folding, we also incorporate a pipelining strategy in the design methodology. A complete decoder has been prototyped for proof of concept, and is publicly available. Another specific high-performance design of an LDPC decoder based on this methodology was worked out in past, and has been p...

  11. A cost-effective methodology for the design of massively-parallel VLSI functional units

    Science.gov (United States)

    Venkateswaran, N.; Sriram, G.; Desouza, J.

    1993-01-01

    In this paper we propose a generalized methodology for the design of cost-effective massively-parallel VLSI Functional Units. This methodology is based on a technique of generating and reducing a massive bit-array on the mask-programmable PAcube VLSI array. This methodology unifies (maintains identical data flow and control) the execution of complex arithmetic functions on PAcube arrays. It is highly regular, expandable and uniform with respect to problem-size and wordlength, thereby reducing the communication complexity. The memory-functional unit interface is regular and expandable. Using this technique functional units of dedicated processors can be mask-programmed on the naked PAcube arrays, reducing the turn-around time. The production cost of such dedicated processors can be drastically reduced since the naked PAcube arrays can be mass-produced. Analysis of the the performance of functional units designed by our method yields promising results.

  12. Design of batch operations: Systematic methodology for generation and analysis of sustainable alternatives

    DEFF Research Database (Denmark)

    Carvalho, Ana; Matos, Henrique A.; Gani, Rafiqul

    2010-01-01

    The objective of this paper is to present a new methodology that is able to generate, screen and identify sustainable alternatives to continuous chemical processes as well as processes operating in the batch mode. The methodology generates the sustainable (design) alternatives by locating...... the operational, environmental, economical and safety related problems inherent in the process (batch or continuous). Alternatives that are more sustainable, compared to a reference, are generated and evaluated by addressing one or more of the identified problems. A decomposition technique as well as a set...... processes are described, highlighting the main differences between them. Through two case studies, the application of the methodology, to obtain sustainable design alternatives for batch plants, is highlighted....

  13. BEAM STOP DESIGN METHODOLOGY AND DESCRIPTION OF A NEW SNS BEAM STOP

    Energy Technology Data Exchange (ETDEWEB)

    Polsky, Yarom [ORNL; Plum, Michael A [ORNL; Geoghegan, Patrick J [ORNL; Jacobs, Lorelei L [ORNL; Lu, Wei [ORNL; McTeer, Stephen Mark [ORNL

    2010-01-01

    The design of accelerator components such as magnets, accelerator cavities and beam instruments tends to be a fairly standardized and collective effort within the particle accelerator community with well established performance, reliability and, in some cases, even budgetary criteria. Beam stop design, by contrast, has been comparatively subjective historically with much more general goals. This lack of rigor has lead to a variety of facility implementations with limited standardization and minimal consensus on approach to development within the particle accelerator community. At the Spallation Neutron Source (SNS), for example, there are four high power beam stops in use, three of which have significantly different design solutions. This paper describes the design of a new off-momentum beam stop for the SNS. The technical description of the system will be complemented by a discussion of design methodology. This paper presented an overview of the new SNS HEBT off-momentum beam stop and outlined a methodology for beam stop system design. The new beam stop consists of aluminium and steel blocks cooled by a closed-loop forced-air system and is expected to be commissioned this summer. The design methodology outlined in the paper represents a basic description of the process, data, analyses and critical decisions involved in the development of a beam stop system.

  14. A Flexible System Level Design Methodology Targeting Run-Time Reconfigurable FPGAs

    Directory of Open Access Journals (Sweden)

    Houzet Dominique

    2007-01-01

    Full Text Available Abstract Reconfigurable computing is certainly one of the most important emerging research topics on digital processing architectures over the last few years. The introduction of run-time reconfiguration (RTR on FPGAs requires appropriate design flows and methodologies to fully exploit this new functionality. For that purpose, we present an automatic design generation methodology for heterogeneous architectures based on DSPs and FPGAs that ease and speed RTR implementation. We focus on how to take into account specificities of partially reconfigurable components from a high-level specification during the design generation steps. This method automatically generates designs for both fixed and partially reconfigurable parts of an FPGA with automatic management of the reconfiguration process. Furthermore, this automatic design generation enables a reconfiguration prefetching technique to minimize reconfiguration latency and buffer-merging techniques to minimize memory requirements of the generated design. This concept has been applied to different wireless access schemes, based on a combination of OFDM and CDMA techniques. This implementation example illustrates the benefits of the proposed design methodology.

  15. Laboratory experiments in innovation research: a methodological overview and a review of the current literature

    OpenAIRE

    Brüggemann, Julia; Bizer, Kilian

    2016-01-01

    Innovation research has developed a broad set of methodological approaches in recent decades. In this paper, we propose laboratory experiments as a fruitful methodological addition to the existing methods in innovation research. Therefore, we provide an overview of the existing methods, discuss the advantages and limitations of laboratory experiments, and review experimental studies dealing with different fields of innovation policy, namely intellectual property rights, financial instruments,...

  16. Alcohol mixed with energy drinks: methodology and design of the Utrecht Student Survey

    Science.gov (United States)

    de Haan, Lydia; de Haan, Hein A; Olivier, Berend; Verster, Joris C

    2012-01-01

    This paper describes the methodology of the Utrecht Student Survey. This online survey was conducted in June 2011 by 6002 students living in Utrecht, The Netherlands. The aim of the survey was to determine the potential impact of mixing alcoholic beverages with energy drinks on overall alcohol consumption and alcohol-related consequences. In contrast to most previous surveys conducted on this topic, the current survey used a more appropriate within-subject design, comparing the alcohol consumption of individuals who consume alcohol mixed with energy drinks on occasions. Specifically, a comparison was conducted to examine the occasions during which these individuals consume this mixture versus occasions during which they consume alcohol alone. In addition to energy drinks, the consumption of other non-alcoholic mixers was also assessed when combined with alcoholic beverages. Furthermore, the reasons for consuming energy drinks alone or in combination with alcohol were investigated, and were compared to reasons for mixing alcohol with other non-alcoholic beverages. Finally, personality characteristics and the level of risk-taking behavior among the individuals were also assessed to explore their relationship with alcohol consumption. The Utrecht Student Survey will be replicated in the USA, Australia, and the UK. Results will be pooled, but also examined for possible cross-cultural differences. PMID:23118547

  17. Methodology for Design and Analysis of Reactive Distillation Involving Multielement Systems

    DEFF Research Database (Denmark)

    Jantharasuk, Amnart; Gani, Rafiqul; Górak, Andrzej;

    2011-01-01

    A new methodology for design and analysis of reactive distillation has been developed. In this work, the elementbased approach, coupled with a driving force diagram, has been extended and applied to the design of a reactive distillation column involving multielement (multicomponent) systems....... The transformation of ordinary systems to element-based ones and the aggregation of non-key elements allow the important design parameters, such as the number of stages, feed stage and minimum reflux ratio, to be determined by using simple diagrams similar to those regularly employed for non-reactive systems...... consisting of two components. Based on this methodology, an optimal design configuration is identified using the equivalent binary-element-driving force diagram. Two case studies of methyl acetate (MeOAc) synthesis and methyl-tert-butyl ether (MTBE) synthesis have been considered to demonstrate...

  18. Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture.

    Science.gov (United States)

    Lam, Jonathan; Carmichael, S Thomas; Lowry, William E; Segura, Tatiana

    2015-03-11

    Bioactive signals can be incorporated in hydrogels to direct encapsulated cell behavior. Design of experiments methodology methodically varies the signals systematically to determine the individual and combinatorial effects of each factor on cell activity. Using this approach enables the optimization of three ligands concentrations (RGD, YIGSR, IKVAV) for the survival and differentiation of neural progenitor cells.

  19. Developing a Design Methodology for Web 2.0 Mediated Learning

    DEFF Research Database (Denmark)

    2010-01-01

    Ed). We describe how this method has been adopted as part of a learning methodology building on concepts and models presented in the other symposium papers, in particular those of active, problem based learning and web 2.0-technologies. The challenge of designing on the basis of an explicit learning...

  20. Mechanistic Methodology for Airport Pavement Design with Engineering Fabrics. Volume 1. Theoretical and Experimental Bases.

    Science.gov (United States)

    1984-08-01

    DOTIFAAIPM-8419,, Mechanistic Methodology for Program Engineering& Airport Pavement Design with Maintenance Service Engineerin Washington, D.C. 20591...Reflective cracks require labor intensive operations for crack sealing and patching, thus becoming a significant maintenance expense item. The problem of...models or prediciting allowable critical strains are not available. The problems are complicated further by the fact that since asphaltic concrete is a

  1. IDR: A Participatory Methodology for Interdisciplinary Design in Technology Enhanced Learning

    Science.gov (United States)

    Winters, Niall; Mor, Yishay

    2008-01-01

    One of the important themes that emerged from the CAL'07 conference was the failure of technology to bring about the expected disruptive effect to learning and teaching. We identify one of the causes as an inherent weakness in prevalent development methodologies. While the problem of designing technology for learning is irreducibly…

  2. Building wind design methodology for Italian climatic areas (second report). Advancement

    Energy Technology Data Exchange (ETDEWEB)

    Ciolfi, A. [UTS Engineering, Roma (Italy)

    1994-12-31

    The present work, carried out through information of the Meteorological Service of the Italian Military Aeronautic, is the first step to carry out a bioclimatic design methodology based on monitored statistical dates of wind characteristics in Italian climatic areas. The first dates obtained are relative to climatic areas of littoral latium and middle interland and they are: Pratica di Mare, Fiumicino, Ciampino, Guidonia. (orig.)

  3. Beyond Needs Analysis: Soft Systems Methodology for Meaningful Collaboration in EAP Course Design

    Science.gov (United States)

    Tajino, Akira; James, Robert; Kijima, Kyoichi

    2005-01-01

    Designing an EAP course requires collaboration among various concerned stakeholders, including students, subject teachers, institutional administrators and EAP teachers themselves. While needs analysis is often considered fundamental to EAP, alternative research methodologies may be required to facilitate meaningful collaboration between these…

  4. Using Delphi Methodology to Design Assessments of Teachers' Pedagogical Content Knowledge

    Science.gov (United States)

    Manizade, Agida Gabil; Mason, Marguerite M.

    2011-01-01

    Descriptions of methodologies that can be used to create items for assessing teachers' "professionally situated" knowledge are lacking in mathematics education research literature. In this study, researchers described and used the Delphi method to design an instrument to measure teachers' pedagogical content knowledge. The instrument focused on a…

  5. QFD: a methodological tool for integration of ergonomics at the design stage.

    Science.gov (United States)

    Marsot, Jacques

    2005-03-01

    As a marked increase in the number of musculoskeletal disorders was noted in many industrialized countries and more specifically in companies that require the use of hand tools, the French National Research and Safety Institute launched in 1999 a research program on the topic of integrating ergonomics into hand tool design. After a brief review of the problems of integrating ergonomics at the design stage, the paper shows how the "Quality Function Deployment" method has been applied to the design of a boning knife and it highlights the difficulties encountered. Then, it demonstrates how this method can be a methodological tool geared to greater ergonomics consideration in product design.

  6. Design Methodology of the Structure of Postal Express Mail Networks of Aviation Channels in China

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    On the basis of the postal area center office system, the continuous space approximation is used to study the structure of postal express mail networks of aviation channels in China. Tradeoffs among sorting, handling, transportation, administrative and facilities costs are examined. The optimizing design methodology proposed in this paper can be used to analyze and design the postal express mail network. The objective is to minimize the total system cost.

  7. Development of six sigma concurrent parameter and tolerance design method based on response surface methodology

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Using Response Surface Methodology (RSM), an optimizing model of concurrent parameter and tolerance design is proposed where response mean equals its target in the target being best. The optimizing function of the model is the sum of quality loss and tolerance cost subjecting to the variance confidence region of which six sigma capability can be assured. An example is illustrated in order to compare the differences between the developed model and the parameter design with minimum variance. The results show ...

  8. A low-power photovoltaic system with energy storage for radio communications: Description and design methodology

    Science.gov (United States)

    Chapman, C. P.; Chapman, P. D.; Lewison, A. H.

    1982-01-01

    A low power photovoltaic system was constructed with approximately 500 amp hours of battery energy storage to provide power to an emergency amateur radio communications center. The system can power the communications center for about 72 hours of continuous nonsun operation. Complete construction details and a design methodology algorithm are given with abundant engineering data and adequate theory to allow similar systems to be constructed, scaled up or down, with minimum design effort.

  9. A hydrodynamic optimization design methodology for a ship bulbous bow under multiple operating conditions

    OpenAIRE

    Yu Lu; Xin Chang; An-kang Hu

    2016-01-01

    The main objective of this article is to describe an innovative methodology for the hydrodynamic optimization of a ship bulbous bow which considers multiple operating conditions. The proposed method is more practical and effective than the traditional optimization process, which is only based on contractually specified design condition. Parametric form approaches are adopted by employing an F-spline curve in order to generate variants of the hull bulbous bow forms using form design parameters...

  10. Biomechatronic Design in Biotechnology A Methodology for Development of Biotechnological Products

    CERN Document Server

    Mandenius, Carl-Fredrik

    2011-01-01

    This cutting-edge guide on the fundamentals, theory, and applications of biomechatronic design principles Biomechatronic Design in Biotechnology presents a complete methodology of biomechatronics, an emerging variant of the mechatronics field that marries biology, electronics, and mechanics to create products where biological and biochemical, technical, human, management-and-goal, and information systems are combined and integrated in order to solve a mission that fulfills a human need. A biomechatronic product includes a biological, mechanical, and electronic part. Beginning with an overvie

  11. Methodology for design of adaptive interfaces for diagnostic workstations with integrated images and reports

    Science.gov (United States)

    Harreld, Michael R.; Valentino, Daniel J.; Liu, Brent J.; El-Saden, Suzie; Duckwiler, Gary R.

    1998-06-01

    Diagnostic workstations have generally lacked acceptance due to awkward interfaces, poor usability and lack of clinical data integration. We developed a new methodology for the design and implementation of diagnostic workstations and applied the methodology in diagnostic neuroradiology. The methodology facilitated the objective design and evaluation of optimal diagnostic features, including the integration of images and reports, and the implementation of intelligent and adaptive graphical user interfaces. As a test of this new methodology, we developed and evaluated a neuroradiological diagnostic workstation. The general goals of diagnostic neuroradiologists were modeled and directly used in the design of the UCLA Digital ViewBox, an object-oriented toolkit for medical imaging workstations. For case-specific goals, an object-oriented protocol toolkit was developed for rapid development and integration of new protocols, modes, and tools. Each protocol defines a way to arrange and process data in order to accomplish diagnostic goals that are specific to anatomy (e.g., a spine protocol), or to a suspected pathology (e.g., a tumor protocol). Each protocol was divided into modes that represent diagnostic reading tasks. Each mode was further broken down into functions supporting that task. Via a data mediator engine, the workstation communicated with clinical data repositories, including the UCLA HIS, Clinical RIS/PACS and individual DICOM compatible scanners. The data mediator served to transparently integrate, retrieve, and cache image and report data. Task-oriented Reading protocols automatically present the appropriate diagnostic information and diagnostic tools to the radiologist. We describe a protocol toolkit that enables the rapid design and implementation of customized reading protocols. We also present an intelligent layer that enables the automatic presentation of the appropriate information. This new methodology for diagnostic workstation design led to an

  12. Optimization and Design of a Low Power Switched Current A/D Sigma-Delta-Modulator for Voice Band Applications

    DEFF Research Database (Denmark)

    Jørgensen, Ivan Harald Holger; Bogason, Gudmundur

    1998-01-01

    This paper presents a third order switched current sigma delta-modulator. The modulator is optimized at the system level for minimum power consumption by careful design of the noise transfer function. A thorough noise analysis of the cascode type current copiers used to implement the modulator......, together with a new methodology for evaluating the nonlinear settling behavior is presented. This leads to a new optimization methodology that minimize the power consumption in switched current circuits for given design parameters. The optimization methodology takes process variations into account...... to internal clamping in the integrators and proper scaling the modulator shows excellent stability properties. In order to compare the performance of the modulator presented in this paper to other sigma delta-modulators two figure-of-merits (FOMs) are proposed. From these figure-of-merits it is found...

  13. Cognitive Activity-based Design Methodology for Novice Visual Communication Designers

    Science.gov (United States)

    Kim, Hyunjung; Lee, Hyunju

    2016-01-01

    The notion of design thinking is becoming more concrete nowadays, as design researchers and practitioners study the thinking processes involved in design and employ the concept of design thinking to foster better solutions to complex and ill-defined problems. The goal of the present research is to develop a cognitive activity-based design…

  14. A methodology for the sustainable design and implementation strategy of CO2 utilization processes

    DEFF Research Database (Denmark)

    Roh, Kosan; Frauzem, Rebecca; Nguyen, Tuan B. H.

    2016-01-01

    design and analysis is discussed as only limited amounts of process data is available for determining the optimal processing path and in the third stage the issue of implementation strategy is considered. As examples, two CO2 utilization methods for methanol production, combined reforming and direct......This work presents a systematic methodology that has been developed for the design of sustainable CO2 utilization processes that can mitigate CO2 and also guarantee profitability. First, the three-stage methodology, evaluation criteria and applicable tools are described. Especially, the process...... synthesis are considered. Methanol plants employing such methods are developed using synthesis-design and simulation tools and their evaluation indicators are calculated under various implementation strategies. It is demonstrated that integrating or replacing an existing conventional methanol plant...

  15. Application of Design Methodologies for Feedback Compensation Associated with Linear Systems

    Science.gov (United States)

    Smith, Monty J.

    1996-01-01

    The work that follows is concerned with the application of design methodologies for feedback compensation associated with linear systems. In general, the intent is to provide a well behaved closed loop system in terms of stability and robustness (internal signals remain bounded with a certain amount of uncertainty) and simultaneously achieve an acceptable level of performance. The approach here has been to convert the closed loop system and control synthesis problem into the interpolation setting. The interpolation formulation then serves as our mathematical representation of the design process. Lifting techniques have been used to solve the corresponding interpolation and control synthesis problems. Several applications using this multiobjective design methodology have been included to show the effectiveness of these techniques. In particular, the mixed H 2-H performance criteria with algorithm has been used on several examples including an F-18 HARV (High Angle of Attack Research Vehicle) for sensitivity performance.

  16. Aero-Mechanical Design Methodology for Subsonic Civil Transport High-Lift Systems

    Science.gov (United States)

    vanDam, C. P.; Shaw, S. G.; VanderKam, J. C.; Brodeur, R. R.; Rudolph, P. K. C.; Kinney, D.

    2000-01-01

    In today's highly competitive and economically driven commercial aviation market, the trend is to make aircraft systems simpler and to shorten their design cycle which reduces recurring, non-recurring and operating costs. One such system is the high-lift system. A methodology has been developed which merges aerodynamic data with kinematic analysis of the trailing-edge flap mechanism with minimum mechanism definition required. This methodology provides quick and accurate aerodynamic performance prediction for a given flap deployment mechanism early on in the high-lift system preliminary design stage. Sample analysis results for four different deployment mechanisms are presented as well as descriptions of the aerodynamic and mechanism data required for evaluation. Extensions to interactive design capabilities are also discussed.

  17. Systemic design methodologies for electrical energy systems analysis, synthesis and management

    CERN Document Server

    Roboam, Xavier

    2012-01-01

    This book proposes systemic design methodologies applied to electrical energy systems, in particular analysis and system management, modeling and sizing tools. It includes 8 chapters: after an introduction to the systemic approach (history, basics & fundamental issues, index terms) for designing energy systems, this book presents two different graphical formalisms especially dedicated to multidisciplinary devices modeling, synthesis and analysis: Bond Graph and COG/EMR. Other systemic analysis approaches for quality and stability of systems, as well as for safety and robustness analysis tools are also proposed. One chapter is dedicated to energy management and another is focused on Monte Carlo algorithms for electrical systems and networks sizing. The aim of this book is to summarize design methodologies based in particular on a systemic viewpoint, by considering the system as a whole. These methods and tools are proposed by the most important French research laboratories, which have many scientific partn...

  18. Design Methodology of a Dual-Halbach Array Linear Actuator with Thermal-Electromagnetic Coupling.

    Science.gov (United States)

    Eckert, Paulo Roberto; Flores Filho, Aly Ferreira; Perondi, Eduardo; Ferri, Jeferson; Goltz, Evandro

    2016-01-01

    This paper proposes a design methodology for linear actuators, considering thermal and electromagnetic coupling with geometrical and temperature constraints, that maximizes force density and minimizes force ripple. The method allows defining an actuator for given specifications in a step-by-step way so that requirements are met and the temperature within the device is maintained under or equal to its maximum allowed for continuous operation. According to the proposed method, the electromagnetic and thermal models are built with quasi-static parametric finite element models. The methodology was successfully applied to the design of a linear cylindrical actuator with a dual quasi-Halbach array of permanent magnets and a moving-coil. The actuator can produce an axial force of 120 N and a stroke of 80 mm. The paper also presents a comparative analysis between results obtained considering only an electromagnetic model and the thermal-electromagnetic coupled model. This comparison shows that the final designs for both cases differ significantly, especially regarding its active volume and its electrical and magnetic loading. Although in this paper the methodology was employed to design a specific actuator, its structure can be used to design a wide range of linear devices if the parametric models are adjusted for each particular actuator.

  19. MODEL - INTEGRAL METHODOLOGY FOR SUCCESSFUL DESIGNING AND IMPLEMENTING OF TQM SYSTEM IN MACEDONIAN COMPANIES

    Directory of Open Access Journals (Sweden)

    Elizabeta Mitreva

    2011-12-01

    Full Text Available The subject of this paper is linked with the valorization of the meaning and the perspectives of Total Quality Management (TQM system design and implementation within the domestic companies and creating a model-methodology for improved performance, efficiency and effectiveness. The research is designed as an attempt to depict the existing condition in the Macedonian companies regarding quality system design and implementation, analysed through 4 polls in the "house of quality" whose top is the ultimate management, and as its bases measurement, evaluation, analyzing and comparison of the quality are used. This "house" is being held by 4 subsystems e.g. internal standardization, methods and techniques for flawless work performance, education and motivation and analyses of the quality costs. The data received from the research and the proposal of the integral methodology for designing and implementing of TQM system are designed in turn to help and present useful directions to all Macedonian companies tending to become "world class" organizations. The basis in the creation of this model is the redesign of the business processes which afterword begins as a new phase of the business performance - continued improvement, rolling of Deming's Quality Circle (Plan-Do-Check-Act. The model-methodology proposed in this paper is integral and universal which means that it is applicable to all companies regardless of the business area.

  20. A General Design Methodology for Synchronous Early-Completion-Prediction Adders in Nano-CMOS DSP Architectures

    Directory of Open Access Journals (Sweden)

    Mauro Olivieri

    2013-01-01

    Full Text Available Synchronous early-completion-prediction adders (ECPAs are used for high clock rate and high-precision DSP datapaths, as they allow a dominant amount of single-cycle operations even if the worst-case carry propagation delay is longer than the clock period. Previous works have also demonstrated ECPA advantages for average leakage reduction and NBTI effects reduction in nanoscale CMOS technologies. This paper illustrates a general systematic methodology to design ECPA units, targeting nanoscale CMOS technologies, which is not available in the current literature yet. The method is fully compatible with standard VLSI macrocell design tools and standard adder structures and includes automatic definition of critical test patterns for postlayout verification. A design example is included, reporting speed and power data superior to previous works.

  1. Design of BEPC Ⅱ bunch current monitor system

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lei; MA Hui-Zhou; YUE Jun-Hui; LEI Ge; CAO Jian-She; MA Li

    2008-01-01

    BEPC Ⅱ is an electron-positron collider designed to run under multi-bunches and high beam current condition. The accelerator consists of an electron ring, a positron ring and a linear injector. In order to achieve the target luminosity and implement the equal bunch charge injection, the Bunch Current Monitor (BCM)system is built on BEPC Ⅱ. The BCM system consists of three parts: the front-end circuit, the bunch current acquisition system and the bucket selection system. The control software of BCM is based on VxWorks and EPICS. With the help of BCM system, the bunch current in each bucket can be monitored in the Central Control Room. The BEPC Ⅱ timing system can also use the bunch current database to decide which bucket needs to refill to implement "top-off" injection.

  2. A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

    DEFF Research Database (Denmark)

    Lutze, Philip; Woodley, John; Gani, Rafiqul

    be intensified for biggest improvement, process synthesis and design tools are applied which results in the development of a systematic methodology incorporating PI. In order to manage the complexity of PI process options in which a feasible and optimal process solution may exist, the solution procedure......Process intensification (PI) has the potential to improve existing processes or create new process options which are needed in order to produce products using more sustainable methods. Potentially, PI creates an enormous number of process options. For identification where and how the process should...... of this methodology is based on the decomposition approach. Starting from an analysis of existing processes, this methodology generates a set of feasible process options and reduces their number through several screening steps until from the remaining feasible options, the optimal is found. In this presentation...

  3. Design for Sustainability: Current Trends in Sustainable Product Design and Development

    Directory of Open Access Journals (Sweden)

    Marcel Crul

    2009-08-01

    Full Text Available The Design for Sustainability (D4S concept outlines methodologies for making sustainable improvements (social, economic and environmental to products by applying elements of life cycle thinking. D4S builds on the work of ecodesign to include economic and social concerns, and its methodology includes both incremental and radical innovation. The United Nations Environment Programme and the Delft University of Technology, the Netherlands, in concert with key partners, work to support, illustrate, and diffuse targeted D4S demonstration efforts, including the European Commission-funded Cleaner Production for Better Products project in Vietnam, that are needed to change unsustainable consumption and production patterns.

  4. Design methodology for flexible energy conversion systems accounting for dynamic performance

    DEFF Research Database (Denmark)

    Pierobon, Leonardo; Casati, Emiliano; Casella, Francesco

    2014-01-01

    This article presents a methodology to help in the definition of the optimal design of power generation systems. The innovative element is the integration of requirements on dynamic performance into the system design procedure. Operational flexibility is an increasingly important specification...... of these simulations are used within the framework of a multi-objective optimization procedure to identify a number of equally optimal system configurations. A dynamic model of each of these systems is automatically parameterized, by inheriting its parameters values from the design model. Dynamic simulations allow...

  5. Design and current progress of the Apollon 10 PW project

    Institute of Scientific and Technical Information of China (English)

    J.P.Zou; C.Le Blanc; D.N.Papadopoulos; G.Chériaux; P.Georges; G.Mennerat; F.Druon; L.Lecherbourg; A.Pellegrina; P.Ramirez; F.Giambruno; A.Fréneaux; F.Leconte; D.Badarau; J.M.Boudenne; D.Fournet; T.Valloton; J.L.Paillard; J.L.Veray; M.Pina; P.Monot; J.P.Chambaret; P.Martin; F.Mathieu; P.Audebert; F.Amiranoff

    2015-01-01

    The objective of the Apollon project is the generation of 10 PW peak power pulses of 15 fs at 1 shot/minute. In this paper the Apollon facility design, the technological challenges and the current progress of the project will be presented.

  6. Games and Diabetes: A Review Investigating Theoretical Frameworks, Evaluation Methodologies, and Opportunities for Design Grounded in Learning Theories.

    Science.gov (United States)

    Lazem, Shaimaa; Webster, Mary; Holmes, Wayne; Wolf, Motje

    2015-09-02

    Here we review 18 articles that describe the design and evaluation of 1 or more games for diabetes from technical, methodological, and theoretical perspectives. We undertook searches covering the period 2010 to May 2015 in the ACM, IEEE, Journal of Medical Internet Research, Studies in Health Technology and Informatics, and Google Scholar online databases using the keywords "children," "computer games," "diabetes," "games," "type 1," and "type 2" in various Boolean combinations. The review sets out to establish, for future research, an understanding of the current landscape of digital games designed for children with diabetes. We briefly explored the use and impact of well-established learning theories in such games. The most frequently mentioned theoretical frameworks were social cognitive theory and social constructivism. Due to the limitations of the reported evaluation methodologies, little evidence was found to support the strong promise of games for diabetes. Furthermore, we could not establish a relation between design features and the game outcomes. We argue that an in-depth discussion about the extent to which learning theories could and should be manifested in the design decisions is required. © 2015 Diabetes Technology Society.

  7. Impact of User-Centered Design Methodology on the Design of Information Systems.

    Science.gov (United States)

    Sugar, William A.

    1995-01-01

    Examines the implications of incorporating user-centered design within information systems design practices. Highlights include a definition of user-centered design based on human-computer interface; questions asked about users, including outcome, process, and task variables; and three criteria for when to use this approach in information systems…

  8. Development of an aggregation methodology for risk analysis in aerospace conceptual vehicle design

    Science.gov (United States)

    Chytka, Trina Marsh

    2003-10-01

    The growing complexity of technical systems has emphasized a need to gather as much information as possible regarding specific systems of interest in order to make robust, sound decisions about their design and deployment. Acquiring as much data as possible requires the use of empirical statistics, historical information and expert opinion. In much of the aerospace conceptual design environment, the lack of historical information and infeasibility of gathering empirical data relegates the data collection to expert opinion. The conceptual design of a space vehicle requires input from several disciplines (weights and sizing, operations, trajectory, etc.). In this multidisciplinary environment, the design variables are often not easily quantified and have a high degree of uncertainty associated with their values. Decision-makers must rely on expert assessments of the uncertainty associated with the design variables to evaluate the risk level of a conceptual design. Since multiple experts are often queried for their evaluation of uncertainty, a means to combine/aggregate multiple expert assessments must be developed. Providing decision-makers with a solitary assessment that captures the consensus of the multiple experts would greatly enhance the ability to evaluate risk associated with a conceptual design. The objective of this research has been to develop an aggregation methodology that efficiently combines the uncertainty assessments of multiple experts in multiple disciplines involved in aerospace conceptual design. Bayesian probability augmented by uncertainty modeling and expert calibration was employed in the methodology construction. Appropriate questionnaire techniques were used to acquire expert opinion; the responses served as input distributions to the aggregation algorithm. Application of the derived techniques were applied as part of a larger expert assessment elicitation and calibration study. Results of this research demonstrate that aggregation of

  9. Methodology for the Design of Streamline-Traced External-Compression Supersonic Inlets

    Science.gov (United States)

    Slater, John W.

    2014-01-01

    A design methodology based on streamline-tracing is discussed for the design of external-compression, supersonic inlets for flight below Mach 2.0. The methodology establishes a supersonic compression surface and capture cross-section by tracing streamlines through an axisymmetric Busemann flowfield. The compression system of shock and Mach waves is altered through modifications to the leading edge and shoulder of the compression surface. An external terminal shock is established to create subsonic flow which is diffused in the subsonic diffuser. The design methodology was implemented into the SUPIN inlet design tool. SUPIN uses specified design factors to design the inlets and computes the inlet performance, which includes the flow rates, total pressure recovery, and wave drag. A design study was conducted using SUPIN and the Wind-US computational fluid dynamics code to design and analyze the properties of two streamline-traced, external-compression (STEX) supersonic inlets for Mach 1.6 freestream conditions. The STEX inlets were compared to axisymmetric pitot, two-dimensional, and axisymmetric spike inlets. The STEX inlets had slightly lower total pressure recovery and higher levels of total pressure distortion than the axisymmetric spike inlet. The cowl wave drag coefficients of the STEX inlets were 20% of those for the axisymmetric spike inlet. The STEX inlets had external sound pressures that were 37% of those of the axisymmetric spike inlet, which may result in lower adverse sonic boom characteristics. The flexibility of the shape of the capture cross-section may result in benefits for the integration of STEX inlets with aircraft.

  10. Engineering design of a high-temperature superconductor current lead

    Science.gov (United States)

    Niemann, R. C.; Cha, Y. S.; Hull, J. R.; Daugherty, M. A.; Buckles, W. E.

    As part of the US Department of Energy's Superconductivity Pilot Center Program, Argonne National Laboratory and Superconductivity, Inc., are developing high-temperature superconductor (HTS) current leads suitable for application to superconducting magnetic energy storage systems. The principal objective of the development program is to design, construct, and evaluate the performance of HTS current leads suitable for near-term applications. Supporting objectives are to (1) develop performance criteria; (2) develop a detailed design; (3) analyze performance; (4) gain manufacturing experience in the areas of materials and components procurement, fabrication and assembly, quality assurance, and cost; (5) measure performance of critical components and the overall assembly; (6) identify design uncertainties and develop a program for their study; and (7) develop application-acceptance criteria.

  11. Current applications and future directions for the CDISC Operational Data Model standard: A methodological review.

    Science.gov (United States)

    Hume, Sam; Aerts, Jozef; Sarnikar, Surendra; Huser, Vojtech

    2016-04-01

    In order to further advance research and development on the Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM) standard, the existing research must be well understood. This paper presents a methodological review of the ODM literature. Specifically, it develops a classification schema to categorize the ODM literature according to how the standard has been applied within the clinical research data lifecycle. This paper suggests areas for future research and development that address ODM's limitations and capitalize on its strengths to support new trends in clinical research informatics. A systematic scan of the following databases was performed: (1) ABI/Inform, (2) ACM Digital, (3) AIS eLibrary, (4) Europe Central PubMed, (5) Google Scholar, (5) IEEE Xplore, (7) PubMed, and (8) ScienceDirect. A Web of Science citation analysis was also performed. The search term used on all databases was "CDISC ODM." The two primary inclusion criteria were: (1) the research must examine the use of ODM as an information system solution component, or (2) the research must critically evaluate ODM against a stated solution usage scenario. Out of 2686 articles identified, 266 were included in a title level review, resulting in 183 articles. An abstract review followed, resulting in 121 remaining articles; and after a full text scan 69 articles met the inclusion criteria. As the demand for interoperability has increased, ODM has shown remarkable flexibility and has been extended to cover a broad range of data and metadata requirements that reach well beyond ODM's original use cases. This flexibility has yielded research literature that covers a diverse array of topic areas. A classification schema reflecting the use of ODM within the clinical research data lifecycle was created to provide a categorized and consolidated view of the ODM literature. The elements of the framework include: (1) EDC (Electronic Data Capture) and EHR (Electronic Health Record

  12. Optimization design of the stratospheric airship's power system based on the methodology of orthogonal experiment

    Institute of Scientific and Technical Information of China (English)

    Jian LIU; Quan-bao WANG; Hai-tao ZHAO; Ji-an CHEN; Ye QIU; Deng-ping DUAN

    2013-01-01

    The optimization design of the power system is essential for stratospheric airships with paradoxical requirements of high reliability and low weight.The methodology of orthogonal experiment is presented to deal with the problem of the optimization design of the airship's power system.Mathematical models of the solar array,regenerative fuel cell,and power management subsystem (PMS) are presented.The basic theory of the method of orthogonal experiment is discussed,and the selection of factors and levels of the experiment and the choice of the evaluation function are also revealed.The proposed methodology is validated in the optimization design of the power system of the ZhiYuan-2 stratospheric airship.Results show that the optimal configuration is easily obtained through this methodology.Furthermore,the optimal configuration and three sub-optimal configurations are in the Pareto frontier of the design space.Sensitivity analyses for the weight and reliability of the airship's power system are presented.

  13. Prognostics and health management design for rotary machinery systems—Reviews, methodology and applications

    Science.gov (United States)

    Lee, Jay; Wu, Fangji; Zhao, Wenyu; Ghaffari, Masoud; Liao, Linxia; Siegel, David

    2014-01-01

    Much research has been conducted in prognostics and health management (PHM), an emerging field in mechanical engineering that is gaining interest from both academia and industry. Most of these efforts have been in the area of machinery PHM, resulting in the development of many algorithms for this particular application. The majority of these algorithms concentrate on applications involving common rotary machinery components, such as bearings and gears. Knowledge of this prior work is a necessity for any future research efforts to be conducted; however, there has not been a comprehensive overview that details previous and on-going efforts in PHM. In addition, a systematic method for developing and deploying a PHM system has yet to be established. Such a method would enable rapid customization and integration of PHM systems for diverse applications. To address these gaps, this paper provides a comprehensive review of the PHM field, followed by an introduction of a systematic PHM design methodology, 5S methodology, for converting data to prognostics information. This methodology includes procedures for identifying critical components, as well as tools for selecting the most appropriate algorithms for specific applications. Visualization tools are presented for displaying prognostics information in an appropriate fashion for quick and accurate decision making. Industrial case studies are included in this paper to show how this methodology can help in the design of an effective PHM system.

  14. LINKING CLASSROOM AND COMMUNITY: A THEORETICAL ALIGNMENT OF SERVICE LEARNING AND A HUMAN-CENTERED DESIGN METHODOLOGY IN CONTEMPORARY COMMUNICATION DESIGN EDUCATION

    Directory of Open Access Journals (Sweden)

    Anneli Bowie

    2016-04-01

    Full Text Available The current emphasis on social responsibility and community collaboration within higher education has led to an increased drive to include service learning in the curriculum. With its emphasis on mutually beneficial collaborations, service learning can be meaningful for both students and the community, but is challenging to manage successfully. From a design education perspective, it is interesting to note that contemporary design practice emphasises a similar approach known as a human-centered design, where users are considered and included throughout the design process. In considering both service learning and human-centred design as foundations for design pedagogy, various philosophical and methodological similarities are evident. The paper explores the relationship between a service learning community engagement approach and a human-centered design approach in contemporary communication design education. To this end, each approach is considered individually after which a joint frame of reference is presented. Butin’s service learning typology, namely the four Rs – respect, reciprocity, relevance and reflection – serves as a point of departure for the joint frame of reference. Lastly, the potential value and relevance of a combined understanding of service learning and human-centered design is considered.

  15. Designing and implementing INTREPID, an intensive program in translational research methodologies for new investigators.

    Science.gov (United States)

    Plottel, Claudia S; Aphinyanaphongs, Yindalon; Shao, Yongzhao; Micoli, Keith J; Fang, Yixin; Goldberg, Judith D; Galeano, Claudia R; Stangel, Jessica H; Chavis-Keeling, Deborah; Hochman, Judith S; Cronstein, Bruce N; Pillinger, Michael H

    2014-12-01

    Senior housestaff and junior faculty are often expected to perform clinical research, yet may not always have the requisite knowledge and skills to do so successfully. Formal degree programs provide such knowledge, but require a significant commitment of time and money. Short-term training programs (days to weeks) provide alternative ways to accrue essential information and acquire fundamental methodological skills. Unfortunately, published information about short-term programs is sparse. To encourage discussion and exchange of ideas regarding such programs, we here share our experience developing and implementing INtensive Training in Research Statistics, Ethics, and Protocol Informatics and Design (INTREPID), a 24-day immersion training program in clinical research methodologies. Designing, planning, and offering INTREPID was feasible, and required significant faculty commitment, support personnel and infrastructure, as well as committed trainees.

  16. Mechanisms and coherences of robust design methodology: a robust design process proposal

    DEFF Research Database (Denmark)

    Göhler, Simon Moritz; Christensen, Martin Ebro; Howard, Thomas J.

    2016-01-01

    Although robust design (RD) methods are recognised as a way of developing mechanical products with consistent and predictable performance and quality, they do not experience widespread success in industry. One reason being the lack of a coherent RD process (RDP). In this contribution we analyse...... the robustness of the design, (3) processing and evaluation of the robustness data and (4) scaling of the design to optimise parameter and tolerance values. For each of the activities, the set of relevant RD methods is presented. The main objective of the RDP is to provide the design team with a better overview...

  17. HPCC Methodologies for Structural Design and Analysis on Parallel and Distributed Computing Platforms

    Science.gov (United States)

    Farhat, Charbel

    1998-01-01

    In this grant, we have proposed a three-year research effort focused on developing High Performance Computation and Communication (HPCC) methodologies for structural analysis on parallel processors and clusters of workstations, with emphasis on reducing the structural design cycle time. Besides consolidating and further improving the FETI solver technology to address plate and shell structures, we have proposed to tackle the following design related issues: (a) parallel coupling and assembly of independently designed and analyzed three-dimensional substructures with non-matching interfaces, (b) fast and smart parallel re-analysis of a given structure after it has undergone design modifications, (c) parallel evaluation of sensitivity operators (derivatives) for design optimization, and (d) fast parallel analysis of mildly nonlinear structures. While our proposal was accepted, support was provided only for one year.

  18. A methodological approach for designing and sequencing product families in Reconfigurable Disassembly Systems

    Directory of Open Access Journals (Sweden)

    Ignacio Eguia

    2011-10-01

    Full Text Available Purpose: A Reconfigurable Disassembly System (RDS represents a new paradigm of automated disassembly system that uses reconfigurable manufacturing technology for fast adaptation to changes in the quantity and mix of products to disassemble. This paper deals with a methodology for designing and sequencing product families in RDS. Design/methodology/approach: The methodology is developed in a two-phase approach, where products are first grouped into families and then families are sequenced through the RDS, computing the required machines and modules configuration for each family. Products are grouped into families based on their common features using a Hierarchical Clustering Algorithm. The optimal sequence of the product families is calculated using a Mixed-Integer Linear Programming model minimizing reconfigurability and operational costs. Findings: This paper is focused to enable reconfigurable manufacturing technologies to attain some degree of adaptability during disassembly automation design using modular machine tools. Research limitations/implications: The MILP model proposed for the second phase is similar to the well-known Travelling Salesman Problem (TSP and therefore its complexity grows exponentially with the number of products to disassemble. In real-world problems, which a higher number of products, it may be advisable to solve the model approximately with heuristics. Practical implications: The importance of industrial recycling and remanufacturing is growing due to increasing environmental and economic pressures. Disassembly is an important part of remanufacturing systems for reuse and recycling purposes. Automatic disassembly techniques have a growing number of applications in the area of electronics, aerospace, construction and industrial equipment. In this paper, a design and scheduling approach is proposed to apply in this area. Originality/value: This paper presents a new concept called Reconfigurable Disassembly System

  19. A Formal Methodology to Design and Deploy Dependable Wireless Sensor Networks.

    Science.gov (United States)

    Testa, Alessandro; Cinque, Marcello; Coronato, Antonio; Augusto, Juan Carlos

    2016-12-23

    Wireless Sensor Networks (WSNs) are being increasingly adopted in critical applications, where verifying the correct operation of sensor nodes is a major concern. Undesired events may undermine the mission of the WSNs. Hence, their effects need to be properly assessed before deployment, to obtain a good level of expected performance; and during the operation, in order to avoid dangerous unexpected results. In this paper, we propose a methodology that aims at assessing and improving the dependability level of WSNs by means of an event-based formal verification technique. The methodology includes a process to guide designers towards the realization of a dependable WSN and a tool ("ADVISES") to simplify its adoption. The tool is applicable to homogeneous WSNs with static routing topologies. It allows the automatic generation of formal specifications used to check correctness properties and evaluate dependability metrics at design time and at runtime for WSNs where an acceptable percentage of faults can be defined. During the runtime, we can check the behavior of the WSN accordingly to the results obtained at design time and we can detect sudden and unexpected failures, in order to trigger recovery procedures. The effectiveness of the methodology is shown in the context of two case studies, as proof-of-concept, aiming to illustrate how the tool is helpful to drive design choices and to check the correctness properties of the WSN at runtime. Although the method scales up to very large WSNs, the applicability of the methodology may be compromised by the state space explosion of the reasoning model, which must be faced by partitioning large topologies into sub-topologies.

  20. A systematic synthesis and design methodology to achieve process intensification in (bio) chemical processes

    OpenAIRE

    Lutze, Philip; Woodley, John; Gani, Rafiqul

    2011-01-01

    Process intensification (PI) has the potential to improve existing processes or create new process options which are needed in order to produce products using more sustainable methods. Potentially, PI creates an enormous number of process options. For identification where and how the process should be intensified for biggest improvement, process synthesis and design tools are applied which results in the development of a systematic methodology incorporating PI. In order to manage the complexi...

  1. Design and Verification Methodology of Boundary Conditions for Finite Volume Schemes

    Science.gov (United States)

    2012-07-01

    Finite Volume Schemes 5a. CONTRACT NUMBER In-House 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Folkner, D., Katz , A and Sankaran...July 9-13, 2012 ICCFD7-2012-1001 Design and Verification Methodology of Boundary Conditions for Finite Volume Schemes D. Folkner∗, A. Katz ∗ and V...Office (ARO), under the supervision of Dr. Frederick Ferguson. The authors would like to thank Dr. Ferguson for his continuing support of this research

  2. Methodology for the design of a stand-alone photovoltaic power supply

    OpenAIRE

    López Seguel,Julio; Seleme Junior,Seleme Isaac; Donoso-Garcia,Pedro F; Ferreira Morais,Lenin Martins; Cabaleiro Cortizo,Porfirio; Severo Mendes,Marcos A

    2013-01-01

    This paper presents a complete methodology for the design of an autonomous photovoltaic system to maximize the use of solar energy. It is a method that prioritizes the best cost-effective choice at every step of the project. In order to ensure the proper use and extended battery life time, a control strategy for charging the batteries is proposed. Experimental results are provided for a stand-alone photovoltaic system with low electrical power, intended primarily for the illumination and basi...

  3. Methodological Considerations in the Design of Large Scale Systems Engineering Processes.

    Science.gov (United States)

    1981-02-01

    Tversky, A., "Prospect Theory : An Analysis of Decision Under Risk", Econometrica, vol. 47, March 1979, pp. 263-291. Inhelder, B. and Piaget , J., The...concerned with the mathematical and behavioral theory of systems. This we will call systems science and operations research. Also, it says that we...will be con- cerned with a combination of these theories . We will denote the effort to obtain this combination systems methodology and design. Finally

  4. The Atomic Intrinsic Integration Approach: A Structured Methodology for the Design of Games for the Conceptual Understanding of Physics

    Science.gov (United States)

    Echeverria, Alejandro; Barrios, Enrique; Nussbaum, Miguel; Amestica, Matias; Leclerc, Sandra

    2012-01-01

    Computer simulations combined with games have been successfully used to teach conceptual physics. However, there is no clear methodology for guiding the design of these types of games. To remedy this, we propose a structured methodology for the design of conceptual physics games that explicitly integrates the principles of the intrinsic…

  5. Methodology and Policy of Designing and Implementing the National Qualification System

    Directory of Open Access Journals (Sweden)

    A. N. Leybovitch

    2012-01-01

    Full Text Available The paper looks at the current research in the field of the new qualification system development, procedures and outcomes of devising its elements and their influence on vocational training development. The author takes the methodology of the system analysis in the labor and training spheres as the scientific basis for solving the above problems.The main emphasis is on the new approach, which provides the comprehensive analysis of the integrated and complete labor process instead of the in-depth analysis of separate specialties. The above approach was developed and applied in the methodological schemes for creating the national qualification framework and professional standards. The research findings include defining the functions and goals of the new qualification system; methodology tools for its formation; current analysis and immediate tasks of the state policy concerning the given sphere. The research is aimed at the practical application of the Russian vocational training at all levels in the course of modernization. The necessary methodology basis is given for devising a new structure of vocational training system, as well as the new generation of educational programs meant to meet the demand for the personnel in the modern Russian economy. The necessity of integrating the approach to labor and training on a new methodological basis is substantiated. The introduction of the new qualification framework should correspond with the changes in the assessment mechanism of training outcomes. The existing legal base of the Russian system of vocational training, unable to correlate the vocational training and economy, should be further developed. 

  6. Direct current hybrid breakers: A design and its realization

    Science.gov (United States)

    Atmadji, Ali Mahfudz Surya

    2000-12-01

    The use of semiconductors for electric power circuit breakers instead of conventional breakers remains a utopia when designing fault current interrupters for high power networks. The major problems concerning power semiconductor circuit breakers are the excessive heat losses and their sensitivity to transients. However, conventional breakers are capable of dealing with such matters. A combination of the two methods, or so-called `hybrid breakers', would appear to be a solution; however, hybrid breakers use separate parallel branches for conducting the main current and interrupting the short-circuit current. Such breakers are intended for protecting direct current (DC) traction systems. In this thesis hybrid switching techniques for current limitation and purely solidstate current interruption are investigated for DC breakers. This work analyzes the transient behavior of hybrid breakers and compares their operations with conventional breakers and similar solid-state devices in DC systems. Therefore a hybrid breaker was constructed and tested in a specially designed high power test circuit. A vacuum breaker was chosen as the main breaker in the main conducting path; then a commutation path was connected across the vacuum breaker where it provided current limitation and interruption. The commutation path operated only during any current interruption and the process required additional circuits. These included a certain energy storage, overvoltage suppressor and commutation switch. So that when discharging this energy, a controlled counter-current injection could be produced. That counter-current opposed the main current in the breaker by superposition in order to create a forced current-zero. One-stage and two-stage commutation circuits have been treated extensively. This study project contains both theoretical and experimental investigations. A direct current shortcircuit source was constructed capable of delivering power equivalent to a fault. It supplied a direct

  7. COMBINATION OF INDEPENDENT COMPONENT ANALYSIS, DESIGN OF EXPERIMENTS AND DESIGN SPACE FOR A NOVEL METHODOLOGY TO DEVELOP CHROMATOGRAPHIC METHODS

    OpenAIRE

    Rozet, Eric; Debrus, Benjamin; Lebrun, Pierre; Boulanger, B.; Hubert, Philippe

    2012-01-01

    As defined by ICH [1] and FDA, Quality by Design (QbD) stands for “a systematic approach to development that begins with predefined objectives and emphasizes product and process understanding and process control, based on sound science and quality risk management”. A risk–based QbD–compliant approach is proposed for the robust development of analytical methods. This methodology based on Design of Experiments (DoE) to study the experimental domain models the retention times at the beginning, t...

  8. AN INTEGRATED METHODOLOGY FOR LAYOUT DESIGN AND WORK ORGANISATION IN A FURNITURE MANUFACTURING PLANT

    Directory of Open Access Journals (Sweden)

    A. Sutcu

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: This study aims to provide an integrated methodology for re-designing the layout and departmental organisation in a job shop environment. While several studies have discussed the specific re-design or re-organisation of small- and medium-sized enterprises (SMEs through simulation or mathematical models performing improvements, an integrated approach is rare. An integrated simulation-based methodology has been developed for simultaneously re-designing the layout and the departmental organisation of an SME manufacturing facility. A wooden chair manufacturing facility has been used as a case study. It is found that the developed methodology might be useful for other SME manufacturing firms, especially in the furniture industry.

    AFRIKAANSE OPSOMMING: Hierdie studie hou ‘n geïntegreerde metodologie vir die herontwerp van uitleg en departementele rangskikking in ‘n stukwerkwinkel voor. Terwyl verskeie studies die spesifieke herontwerp en herrangskikking van klein- en mediumgrootte ondernemings deur simulasie en wiskundige modelle probeer verbeter, is ‘n geïntegreerde benadering raar. ‘n Geïntegreerde simulasie-gebaseerde metodologie is ontwikkel en ‘n vervaardigingsaanleg wat houtstoele produseer word as gevallestudie voorgehou. Die toepassing van die model word as nuttig beskou vir ander klein- tot mediumgrootte ondernemings in die meubelbedryf.

  9. A hydrodynamic optimization design methodology for a ship bulbous bow under multiple operating conditions

    Directory of Open Access Journals (Sweden)

    Yu Lu

    2016-01-01

    Full Text Available The main objective of this article is to describe an innovative methodology for the hydrodynamic optimization of a ship bulbous bow which considers multiple operating conditions. The proposed method is more practical and effective than the traditional optimization process, which is only based on contractually specified design condition. Parametric form approaches are adopted by employing an F-spline curve in order to generate variants of the hull bulbous bow forms using form design parameters modified, resulting in an optimization system based on improved genetic algorithms. The Rankine source panel method is used for the hydrodynamic evaluation, wherein non-linear free surface conditions and the trim and sinkage of the ship are taken into consideration. The validity and effectiveness of the proposed methodology for a large container ship is investigated by comparing the computational results with experimental data, which demonstrates that the proposed methodology can engage well in the automation process and improve hydrodynamic performance during actual ship design practices.

  10. Current Methodologies and Implications of Phase Identification of the Vertical Jump: A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Eagles, Alexander Neale; Sayers, Mark Gregory Leigh; Bousson, Matthew; Lovell, Dale Ingham

    2015-09-01

    The vertical jump (VJ) is considered a key indicator of lower limb explosive strength. Previous research has established that rate of force development and time to peak force are linked closely to athletic ability and hence the ability to extract these accurately is of significance. The objectives of this study were to (1) review the literature to ascertain what methods are currently used to extract jump phases from the force platform data and (2) compare identified methods on neutral data. In Part 1, an electronic search was conducted using PubMed, Central, and EBSCO host (January 1965 to April 2014). Articles were included if they (1) detailed how VJ phases from the force platform data were identified and (2) used only force platform data in the analysis. Additionally, study design and quality was independently examined. In Part 2, the three common methodologies identified were used to analyze a neutral pool of data to determine if any variance existed. For Part 1, a total of 19 studies met the inclusion criteria. Meta-analysis determined three methods of phase identification used in the literature from which to extract force-time variables. In Part 2, a one-way analysis of variance and Scheffe's post-hoc tests showed significant differences (p < 0.01) for force-time variables (eccentric phase time, concentric phase time, time to peak force, rate of force development) between methods. The results demonstrate that three common methods exist for determination of the VJ phases from force platform data. Consequently, each produce different values for force-time variables when used on a neutral data pool. There is a clear need for a robust agreed method for VJ analysis.

  11. Design for end of life: a design methodology for the early stages of an innovation process

    NARCIS (Netherlands)

    Peeters, J.R.; Dewulf, K.R.

    2012-01-01

    The first phases of the engineering design process, such as the problem definition, the information gathering and the idea generation phase, are commonly considered as important steps in product development, since the cost of a product is assumed to be largely determined within these design

  12. Design for end of life: a design methodology for the early stages of an innovation process

    NARCIS (Netherlands)

    Peeters, J.R.; Dewulf, K.R.

    2012-01-01

    The first phases of the engineering design process, such as the problem definition, the information gathering and the idea generation phase, are commonly considered as important steps in product development, since the cost of a product is assumed to be largely determined within these design steps. B

  13. Designed patterns: flexible control of precipitation through electric currents.

    Science.gov (United States)

    Bena, I; Droz, M; Lagzi, I; Martens, K; Rácz, Z; Volford, A

    2008-08-15

    Understanding and controlling precipitation patterns formed in reaction-diffusion processes is of fundamental importance with high potential for technical applications. Here we present a theory showing that precipitation resulting from reactions among charged agents can be controlled by an appropriately designed, time-dependent electric current. Examples of current dynamics yielding periodic bands of prescribed wavelength, as well as more complicated structures are given. The pattern control is demonstrated experimentally using the reaction-diffusion process 2AgNO3 + K2Cr2O7-->under Ag2Cr2O7 + 2KNO3.

  14. A Methodology to Develop Design Support Tools for Stand-alone Photovoltaic Systems in Developing Countries

    Directory of Open Access Journals (Sweden)

    Stefano Mandelli

    2014-08-01

    Full Text Available As pointed out in several analyses, Stand-Alone Photovoltaic systems may be a relevant option for rural electrification in Developing Countries. In this context, Micro and Small Enterprises which supply customized Stand-Alone Photovoltaic systems play a pivotal role in the last-mile-distribution of this technology. Nevertheless, a number of issues limit the development of these enterprises curbing also potential spinoff benefits. A common business bottleneck is the lack of technical skills since usually few people have the expertise to design and formulate estimates for customers. The long-term solution to tackle this issue implies the implementation of a capacity building process, but this solution rarely matches with time-to-market urgency of local enterprises. Therefore, we propose in this study a simple, but general methodology which can be used to set up Design Support Tools for Micro and Small Enterprises that supply Stand-Alone Photovoltaic systems in rural areas of Developing Countries. After a brief review of the techniques and commercial software available to design the targeted technology, we describe the methodology highlighting the structure, the sizing equations and the main features that should be considered in developing a Design Support Tool. Then, we apply the methodology to set up a tool for use in Uganda and we compare the results with two commercial codes (NSolVx and HOMER. The results show that the implemented Design Support Tool develops correct system designs and presents some advantages for being disseminated in rural areas. Indeed it supports the user in providing the input data, selecting the main system components and delivering estimates to customers.

  15. Optimization of hydraulic dampers with the use of Design For Six Sigma methodology

    Directory of Open Access Journals (Sweden)

    D. Sławik

    2010-12-01

    Full Text Available Purpose: The aims of this paper are to identify the root cause of the temporary decrease in the damping force which occurs during the early stage of the stroking cycle’s compression phase, the so-called damping lag, to describe measures of the phenomenon and to present methods for optimizing the design towards minimizing this (negative effect.Design/methodology/approach: A theoretical background is presented in a constructive and computable manner with emphasis on data-driven modeling. The Design For Six Sigma (DFFS approach and tools were used to validate the model statistically and, more importantly, to propose a method for data-driven optimization of the design.Findings: The root cause of the damping lag was confirmed during model validation as being a result of oil aeration. DFFS methodology proved to be useful in achieving design optimality.Research limitations/implications: The statistical model and conclusions drawn from it are only valid in the interior of the investigated region of the parameter space. Additionally, it might not be possible to find a local minimum of the aeration measure (damping lag inside the selected region of the parameter space; a/the (depending on the context global minimum located at the boundary might be the only possible solution.Practical implications: The optimal value of parameters is not unique and thus additional sub-criteria (cost/durability can be imposed. Conducting tests in an organized manner and according to the Six Sigma methodology allows the design optimization process to be expedited and unnecessary costs to be eliminated.Originality/value: Improvements in understanding and measuring aeration effects constitute a clear foundation for further product optimization. Signal post-processing algorithms are essential for the statistical analysis and are the original contribution of this work.

  16. Design automation techniques for high-resolution current folding and interpolating CMOS A/D converters

    Science.gov (United States)

    Gevaert, D.

    2007-05-01

    The design and testing of a 12-bit Analog-to-Digital (A/D) converter, in current mode, arranged in an 8-bit LSB and a 4- bit MSB architecture together with the integration of specialized test building blocks on chip allows the set up of a design automation technique for current folding and interpolation CMOS A/D converter architectures. The presented design methodology focuses on the automation for CMOS A/D building blocks in a flexible target current folding and interpolating architecture for a downscaling technology and for different quality specifications. The comprehensive understanding of all sources of mismatching in the crucial building blocks and the use of physical based mismatch modeling in the prediction of mismatch errors, more adequate and realistic sizing of all transistors will result in an overall area reduction of the A/D converter. In this design the folding degree is 16, the number of folders is 64 and the interpolation level is 4. The number of folders is reduced by creating intermediate folding signals with a 4-level interpolator based on current division techniques. Current comparators detect the zero-crossing between the differential folder output currents. The outputs of the comparators deliver a cyclic thermometer code. The digital synthesis part for decoding and error correction building blocks is a standardized digital standard cell design. The basic building blocks in the target architecture were designed in 0.35μ CMOS technology; they are suitable for topological reuse and are in an automated way downscaled into a 0.18μ CMOS technology.

  17. Design of a Novel Current Balanced Voltage Controlled Delay Element

    Directory of Open Access Journals (Sweden)

    Pooja Saxena

    2014-04-01

    Full Text Available This paper presents a design of fast voltage controlled delay element based on modified version of low noise Current Balanced Logic (CBL. This delay element provides identical rising and falling edge delays controlled by the single control voltage. The post layout tunable delay range is from 140 ps to 800 ps over control voltage range of 0 to 2.1 V. An analysis for the delay element is also presented, which is in agreement with the simulated delays. A Delay Lock Loop (DLL is designed using this delay element to verify its performance.

  18. Current status and future challenges in psychological research of sport injury prediction and prevention : a methodological perspective

    OpenAIRE

    Johnson, Urban; Tranaeus, Ulrika; Ivarsson, Andreas

    2014-01-01

    The purpose of this critical review was to propose methodological developments in sport injury prediction and prevention research. Altogether, 24 studies (e.g., quantitative, qualitative, and prevention intervention studies) conducted from 2006 forward were analysed, related to the “stress-injury model.” The injury prediction studies were mostly based on prospective designs, using regression analysis, and studied trait anxiety and life stress. The qualitative studies used mainly thematic anal...

  19. Single-Case Experimental Designs: A Systematic Review of Published Research and Current Standards

    Science.gov (United States)

    Smith, Justin D.

    2012-01-01

    This article systematically reviews the research design and methodological characteristics of single-case experimental design (SCED) research published in peer-reviewed journals between 2000 and 2010. SCEDs provide researchers with a flexible and viable alternative to group designs with large sample sizes. However, methodological challenges have…

  20. Design of current mirror integration ROIC for snapshot mode operation

    Science.gov (United States)

    Shanker Gupta, Hari; Kiran Kumar, A. S.; Shojaei Baghini, M.; Chakrabarti, Subhananda; Mehta, Sanjeev; Chowdhury, Arup Roy; Sharma, Dinesh K.

    2016-10-01

    Current mirror integration (CMI) read out integrated circuit (ROIC) topology provides a low input impedance to photo-detectors and provides large injection efficiency, large charge handling capacity and snapshot mode operation without in-pixel opamps. The ROIC described in this paper has been implemented with a modified current mirror circuit, with matched PMOS pairs for detector input stage and its biasing. The readout circuit has been designed for 30 × 30 μm2 pixel size, 4 × 4 array size, variable frame rate, 5 Mega pixel per second (Mpps). Experimental performance of the test chip has achieved 15 Me charge handling capacity, a high dynamic range of 83 dB, 99.8% linearity and 99.96% injection efficiency. The ROIC design has been fabricated in 3.3 V 1P6M UMC 180 nm CMOS process and tested up to 5 MHz pixel rate at room and at cryogenic temperature.

  1. A water quality monitoring network design methodology for the selection of critical sampling points: part II.

    Science.gov (United States)

    Strobl, R O; Robillard, P D; Day, R L; Shannon, R D; McDonnell, A J

    2006-11-01

    In order to resolve the spatial component of the design of a water quality monitoring network, a methodology has been developed to identify the critical sampling locations within a watershed. This methodology, called Critical Sampling Points (CSP), focuses on the contaminant total phosphorus (TP), and is applicable to small, predominantly agricultural-forested watersheds. The CSP methodology was translated into a model, called Water Quality Monitoring Station Analysis (WQMSA). It incorporates a geographic information system (GIS) for spatial analysis and data manipulation purposes, a hydrologic/water quality simulation model for estimating TP loads, and an artificial intelligence technology for improved input data representation. The model input data include a number of hydrologic, topographic, soils, vegetative, and land use factors. The model also includes an economic and logistics component. The validity of the CSP methodology was tested on a small experimental Pennsylvanian watershed, for which TP data from a number of single storm events were available for various sampling points within the watershed. A comparison of the ratios of observed to predicted TP loads between sampling points revealed that the model's results were promising.

  2. Adapt Design: A Methodology for Enabling Modular Design for Mission Specific SUAS

    Science.gov (United States)

    2016-08-24

    the application of this approach are presented via the design of several SUAS. The capability of the design paradigm is assessed through a...is succinctly explained via an analogy to Lego® depicted in Figure 2. Lego® bricks contain a number of modular parts that can be constructed into...stakeholders drives a need for providing users with a small set of inputs that can fully capture the mission, without requiring detailed knowledge of

  3. Electrostatic discharge current linear approach and circuit design method

    Energy Technology Data Exchange (ETDEWEB)

    Katsivelis, P. K.; Fotis, G. P.; Gonos, I. F.; Koussiouris, T. G.; Stathopulos, I. A. [School of Electrical and Computer Engineering, National Technical University of Athens, 9 Iroon Polytechniou Str., Zographou 157 80, Athens (Greece)

    2010-11-15

    The electrostatic discharge (ESD) phenomenon is a great threat to all electronic devices and ICs. An electric charge passing rapidly from a charged body to another can seriously harm the last one. However, there is a lack in a linear mathematical approach which will make it possible to design a circuit capable of producing such a sophisticated current waveform. The commonly accepted electrostatic discharge current waveform is the one set by the IEC 61000-4-2. However, the over-simplified circuit included in the same standard is incapable of producing such a waveform. Treating the electrostatic discharge current waveform of the IEC 61000-4-2 as reference, an approximation method, based on Prony's method, is developed and applied in order to obtain a linear system's response. Considering a known input, a method to design a circuit, able to generate this ESD current waveform in presented. The circuit synthesis assumes ideal active elements. A simulation is carried out using the PSpice software. (authors)

  4. Systematic Design Methodology of a Wideband Multibit Continuous-Time Delta-Sigma Modulator

    Directory of Open Access Journals (Sweden)

    Awinash Anand

    2013-01-01

    Full Text Available Systematic design of a low power, wideband and multi-bit continuous-time delta-sigma modulator (CTDSM is presented. The design methodology is illustrated with a 640 MS/s, 20 MHz signal bandwidth 4th order 2-bit CTDMS implemented in 0.18 µm CMOS technology. The implemented design achieves a peak SNDR of 65.7 dB and a high dynamic range of 70 dB while consuming only 19.7 mW from 1.8 V supply. The design achieves a FoM of 0.31 pJ/conv. Direct path compensation is employed for one clock excess loop delay compensation. In the feedforward topology, capacitive summation using the last opamp eliminates extra summation opamp.

  5. Design Aspects and Test of an Inductive Fault Current Limiter

    Directory of Open Access Journals (Sweden)

    Arsénio Pedro

    2014-05-01

    Full Text Available Magnetic shielding inductive fault current limiters with high temperature superconducting tapes are considered as emerging devices that provide technology for the advent of modern power grids. The development of such limiters requires magnetic iron cores and leads to several design challenges regarding the constitutive parts of the limiter, namely the primary and secondary windings. Preliminary tests in a laboratory scale prototype have been carried out considering an assembly designed for simplicity in which the optimization of the magnetic coupling between the primary and secondary was not the main focus. This work addresses the design configuration of an inductive current limiter prototype regarding the assembly of the primary and secondary windings in the core. The prototype is based on a closed magnetic core wound by a primary, built from a normal electric conductor, and a short-circuited secondary, built from first generation superconducting tape. Four different design configurations are considered. Through experimental tests, the performance of such prototype is discussed and compared, in terms of normal and fault operation regimes. The results show that all the configurations assure effective magnetic shielding at normal operation regime, however, at fault operation regime, there are differences among configurations.

  6. Application of quality by design in the current drug development

    Directory of Open Access Journals (Sweden)

    Lan Zhang

    2017-01-01

    Full Text Available Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design (QbD in the field of pharmacy, which is based on the thorough understanding of how materials and process parameters affect the quality profile of final products. The application of QbD in drug formulation and process design is based on a good understanding of the sources of variability and the manufacture process. In this paper, the basic knowledge of QbD, the elements of QbD, steps and tools for QbD implementation in pharmaceutics field, including risk assessment, design of experiment, and process analytical technology (PAT, are introduced briefly. Moreover, the concrete applications of QbD in various pharmaceutical related unit operations are summarized and presented.

  7. A methodology for the design of experiments in computational intelligence with multiple regression models.

    Science.gov (United States)

    Fernandez-Lozano, Carlos; Gestal, Marcos; Munteanu, Cristian R; Dorado, Julian; Pazos, Alejandro

    2016-01-01

    The design of experiments and the validation of the results achieved with them are vital in any research study. This paper focuses on the use of different Machine Learning approaches for regression tasks in the field of Computational Intelligence and especially on a correct comparison between the different results provided for different methods, as those techniques are complex systems that require further study to be fully understood. A methodology commonly accepted in Computational intelligence is implemented in an R package called RRegrs. This package includes ten simple and complex regression models to carry out predictive modeling using Machine Learning and well-known regression algorithms. The framework for experimental design presented herein is evaluated and validated against RRegrs. Our results are different for three out of five state-of-the-art simple datasets and it can be stated that the selection of the best model according to our proposal is statistically significant and relevant. It is of relevance to use a statistical approach to indicate whether the differences are statistically significant using this kind of algorithms. Furthermore, our results with three real complex datasets report different best models than with the previously published methodology. Our final goal is to provide a complete methodology for the use of different steps in order to compare the results obtained in Computational Intelligence problems, as well as from other fields, such as for bioinformatics, cheminformatics, etc., given that our proposal is open and modifiable.

  8. Methodology for designing and manufacturing complex biologically inspired soft robotic fluidic actuators: prosthetic hand case study.

    Science.gov (United States)

    Thompson-Bean, E; Das, R; McDaid, A

    2016-10-31

    We present a novel methodology for the design and manufacture of complex biologically inspired soft robotic fluidic actuators. The methodology is applied to the design and manufacture of a prosthetic for the hand. Real human hands are scanned to produce a 3D model of a finger, and pneumatic networks are implemented within it to produce a biomimetic bending motion. The finger is then partitioned into material sections, and a genetic algorithm based optimization, using finite element analysis, is employed to discover the optimal material for each section. This is based on two biomimetic performance criteria. Two sets of optimizations using two material sets are performed. Promising optimized material arrangements are fabricated using two techniques to validate the optimization routine, and the fabricated and simulated results are compared. We find that the optimization is successful in producing biomimetic soft robotic fingers and that fabrication of the fingers is possible. Limitations and paths for development are discussed. This methodology can be applied for other fluidic soft robotic devices.

  9. A methodology for the design of experiments in computational intelligence with multiple regression models

    Directory of Open Access Journals (Sweden)

    Carlos Fernandez-Lozano

    2016-12-01

    Full Text Available The design of experiments and the validation of the results achieved with them are vital in any research study. This paper focuses on the use of different Machine Learning approaches for regression tasks in the field of Computational Intelligence and especially on a correct comparison between the different results provided for different methods, as those techniques are complex systems that require further study to be fully understood. A methodology commonly accepted in Computational intelligence is implemented in an R package called RRegrs. This package includes ten simple and complex regression models to carry out predictive modeling using Machine Learning and well-known regression algorithms. The framework for experimental design presented herein is evaluated and validated against RRegrs. Our results are different for three out of five state-of-the-art simple datasets and it can be stated that the selection of the best model according to our proposal is statistically significant and relevant. It is of relevance to use a statistical approach to indicate whether the differences are statistically significant using this kind of algorithms. Furthermore, our results with three real complex datasets report different best models than with the previously published methodology. Our final goal is to provide a complete methodology for the use of different steps in order to compare the results obtained in Computational Intelligence problems, as well as from other fields, such as for bioinformatics, cheminformatics, etc., given that our proposal is open and modifiable.

  10. A methodology towards virtualisation-based high performance simulation platform supporting multidisciplinary design of complex products

    Science.gov (United States)

    Ren, Lei; Zhang, Lin; Tao, Fei; (Luke) Zhang, Xiaolong; Luo, Yongliang; Zhang, Yabin

    2012-08-01

    Multidisciplinary design of complex products leads to an increasing demand for high performance simulation (HPS) platforms. One great challenge is how to achieve high efficient utilisation of large-scale simulation resources in distributed and heterogeneous environments. This article reports a virtualisation-based methodology to realise a HPS platform. This research is driven by the issues concerning large-scale simulation resources deployment and complex simulation environment construction, efficient and transparent utilisation of fine-grained simulation resources and high reliable simulation with fault tolerance. A framework of virtualisation-based simulation platform (VSIM) is first proposed. Then the article investigates and discusses key approaches in VSIM, including simulation resources modelling, a method to automatically deploying simulation resources for dynamic construction of system environment, and a live migration mechanism in case of faults in run-time simulation. Furthermore, the proposed methodology is applied to a multidisciplinary design system for aircraft virtual prototyping and some experiments are conducted. The experimental results show that the proposed methodology can (1) significantly improve the utilisation of fine-grained simulation resources, (2) result in a great reduction in deployment time and an increased flexibility for simulation environment construction and (3)achieve fault tolerant simulation.

  11. Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology.

    Science.gov (United States)

    Dong, Jia; Mandenius, Carl-Fredrik; Lübberstedt, Marc; Urbaniak, Thomas; Nüssler, Andreas K N; Knobeloch, Daniel; Gerlach, Jörg C; Zeilinger, Katrin

    2008-07-01

    Optimization of cell culture media based on statistical experimental design methodology is a widely used approach for improving cultivation conditions. We applied this methodology to refine the composition of an established culture medium for growth of a human hepatoma cell line, C3A. A selection of growth factors and nutrient supplements were systematically screened according to standard design of experiments (DoE) procedures. The results of the screening indicated that the medium additives hepatocyte growth factor, oncostatin M, and fibroblast growth factor 4 significantly influenced the metabolic activities of the C3A cell line. Surface response methodology revealed that the optimum levels for these factors were 30 ng/ml for hepatocyte growth factor and 35 ng/ml for oncostatin M. Additional experiments on primary human hepatocyte cultures showed high variance in metabolic activities between cells from different individuals, making determination of optimal levels of factors more difficult. Still, it was possible to conclude that hepatocyte growth factor, epidermal growth factor, and oncostatin M had decisive effects on the metabolic functions of primary human hepatocytes.

  12. Design Methodology of Camshaft Driven Charge Valves for Pneumatic Engine Starts

    Directory of Open Access Journals (Sweden)

    Moser Michael M.

    2015-01-01

    Full Text Available Idling losses constitute a significant amount of the fuel consumption of internal combustion engines. Therefore, shutting down the engine during idling phases can improve its overall efficiency. For driver acceptance a fast restart of the engine must be guaranteed. A fast engine start can be performed using a powerful electric starter and an appropriate battery which are found in hybrid electric vehicles, for example. However, these devices involve additional cost and weight. An alternative method is to use a tank with pressurized air that can be injected directly into the cylinders to start the engine pneumatically. In this paper, pneumatic engine starts using camshaft driven charge valves are discussed. A general methodology for an air-optimal charge valve design is presented which can deal with various requirements. The proposed design methodology is based on a process model representing pneumatic engine operation. A design example for a two-cylinder engine is shown, and the resulting optimized pneumatic start is experimentally verified on a test bench engine. The engine’s idling speed of 1200 rpm can be reached within 350 ms for an initial pressure in the air tank of 10 bar. A detailed system analysis highlights the characteristics of the optimal design found.

  13. Behavioral issues in operations management new trends in design, management, and methodologies

    CERN Document Server

    2013-01-01

    Behavioral Operations Management  has been identified in the last years as one of the most promising emerging fields in Operations Management. Behavioral Issues in Operations Management  explains and examines up-to-date research in this field, which works to analyze the impact of human behavior on the management of complex operating systems.   A collection of studies from leading scholars presents different methodologies and approaches, supported by real data and case studies. Issues such as building trust and strong cooperative relationships with suppliers, enhancing motivation and designing proper incentives for stimulating more effective decision maker behaviours are considered. The main decision-making processes affected by behavioral issues are also analyzed with a focus on new product development, logistics, and supply chain integration.   The broad coverage of methodologies and practical implications makes Behavioral Issues in Operations Management an ideal reference for both researchers developing...

  14. Methodological issues in the design of a rheumatoid arthritis activity score and its cut-offs

    Directory of Open Access Journals (Sweden)

    Collignon O

    2014-07-01

    Full Text Available Olivier Collignon Centre de Recherche Public de la Santé (CRP-Santé, Competences Centre for Methodology and Statistics (CCMS, Strassen, Luxembourg Abstract: Activity of rheumatoid arthritis (RA can be evaluated using several scoring scales based on clinical features. The most widely used one is the Disease Activity Score involving 28 joint counts (DAS28 for which cut-offs were proposed to help physicians classify patients. However, inaccurate scoring can lead to inappropriate medical decisions. In this article some methodological issues in the design of such a score and its cut-offs are highlighted in order to further propose a strategy to overcome them. As long as the issues reviewed in this article are not addressed, results of studies based on standard disease activity scores such as DAS28 should be considered with caution. Keywords: DAS28, disease activity score, penalized logistic regression, clinical prediction, modeling

  15. Three-dimensional design methodologies for tree-based FPGA architecture

    CERN Document Server

    Pangracious, Vinod; Mehrez, Habib

    2015-01-01

    This book focuses on the development of 3D design and implementation methodologies for Tree-based FPGA architecture. It also stresses the needs for new and augmented 3D CAD tools to support designs such as, the design for 3D, to manufacture high performance 3D integrated circuits and reconfigurable FPGA-based systems. This book was written as a text that covers the foundations of 3D integrated system design and FPGA architecture design. It was written for the use in an elective or core course at the graduate level in field of Electrical Engineering, Computer Engineering and Doctoral Research programs. No previous background on 3D integration is required, nevertheless fundamental understanding of 2D CMOS VLSI design is required. It is assumed that reader has taken the core curriculum in Electrical Engineering or Computer Engineering, with courses like CMOS VLSI design, Digital System Design and Microelectronics Circuits being the most important. It is accessible for self-study by both senior students and profe...

  16. Design methodology: edgeless 3D ASICs with complex in-pixel processing for pixel detectors

    Energy Technology Data Exchange (ETDEWEB)

    Fahim Farah, Fahim Farah [Northwestern U. (main); Deptuch, Grzegorz W. [Fermilab; Hoff, James R. [Fermilab; Mohseni, Hooman [Northwestern U. (main)

    2015-08-28

    The design methodology for the development of 3D integrated edgeless pixel detectors with in-pixel processing using Electronic Design Automation (EDA) tools is presented. A large area 3 tier 3D detector with one sensor layer and two ASIC layers containing one analog and one digital tier, is built for x-ray photon time of arrival measurement and imaging. A full custom analog pixel is 65μm x 65μm. It is connected to a sensor pixel of the same size on one side, and on the other side it has approximately 40 connections to the digital pixel. A 32 x 32 edgeless array without any peripheral functional blocks constitutes a sub-chip. The sub-chip is an indivisible unit, which is further arranged in a 6 x 6 array to create the entire 1.248cm x 1.248cm ASIC. Each chip has 720 bump-bond I/O connections, on the back of the digital tier to the ceramic PCB. All the analog tier power and biasing is conveyed through the digital tier from the PCB. The assembly has no peripheral functional blocks, and hence the active area extends to the edge of the detector. This was achieved by using a few flavors of almost identical analog pixels (minimal variation in layout) to allow for peripheral biasing blocks to be placed within pixels. The 1024 pixels within a digital sub-chip array have a variety of full custom, semi-custom and automated timing driven functional blocks placed together. The methodology uses a modified mixed-mode on-top digital implementation flow to not only harness the tool efficiency for timing and floor-planning but also to maintain designer control over compact parasitically aware layout. The methodology uses the Cadence design platform, however it is not limited to this tool.

  17. Novel Charge Sensitive Amplifier Design Methodology suitable for Large Detector Capacitance Applications

    CERN Document Server

    Thomas Noulis a,; Gerard Sarrabayrouse b,c and; Laurent Bary b,c

    2009-01-01

    Current mode charge sensitive amplifier (CSA) topology and related methodology for use as pre-amplification block in radiation detection read out front end IC systems is proposed1. It is based on the use of a suitably configured current conveyor topology providing advantageous noise performance characteristics in comparison to the typical used CSA structures. In the proposed architecture the noise at the output of the CSA is independent of the detector capacitance value, allowing the use of large area detectors without affecting the system noise performance. Theoretical analysis and simulation analysis are performed concerning the operation – performance of the proposed topology. Measurement results on a current mode CSA prototype fabricated with a 0.35 μm CMOS process by Austriamicrosystems are provided supporting the theoretical and simulation results and confirming the performance mainly in terms of the noise performance dependency on the detector capacitance value.

  18. Methodology for risk assessment and reliability applied for pipeline engineering design and industrial valves operation

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, Dierci [Universidade Federal Fluminense (UFF), Volta Redonda, RJ (Brazil). Escola de Engenharia Industrial e Metalurgia. Lab. de Sistemas de Producao e Petroleo e Gas], e-mail: dsilveira@metal.eeimvr.uff.br; Batista, Fabiano [CICERO, Rio das Ostras, RJ (Brazil)

    2009-07-01

    Two kinds of situations may be distinguished for estimating the operating reliability when maneuvering industrial valves and the probability of undesired events in pipelines and industrial plants: situations in which the risk is identified in repetitive cycles of operations and situations in which there is a permanent hazard due to project configurations introduced by decisions during the engineering design definition stage. The estimation of reliability based on the influence of design options requires the choice of a numerical index, which may include a composite of human operating parameters based on biomechanics and ergonomics data. We first consider the design conditions under which the plant or pipeline operator reliability concepts can be applied when operating industrial valves, and then describe in details the ergonomics and biomechanics risks that would lend itself to engineering design database development and human reliability modeling and assessment. This engineering design database development and reliability modeling is based on a group of engineering design and biomechanics parameters likely to lead to over-exertion forces and working postures, which are themselves associated with the functioning of a particular plant or pipeline. This approach to construct based on ergonomics and biomechanics for a more common industrial valve positioning in the plant layout is proposed through the development of a methodology to assess physical efforts and operator reach, combining various elementary operations situations. These procedures can be combined with the genetic algorithm modeling and four elements of the man-machine systems: the individual, the task, the machinery and the environment. The proposed methodology should be viewed not as competing to traditional reliability and risk assessment bur rather as complementary, since it provides parameters related to physical efforts values for valves operation and workspace design and usability. (author)

  19. Methodology to design a municipal solid waste generation and composition map: a case study.

    Science.gov (United States)

    Gallardo, A; Carlos, M; Peris, M; Colomer, F J

    2015-02-01

    The municipal solid waste (MSW) management is an important task that local governments as well as private companies must take into account to protect human health, the environment and to preserve natural resources. To design an adequate MSW management plan the first step consists in defining the waste generation and composition patterns of the town. As these patterns depend on several socio-economic factors it is advisable to organize them previously. Moreover, the waste generation and composition patterns may vary around the town and over the time. Generally, the data are not homogeneous around the city as the number of inhabitants is not constant nor it is the economic activity. Therefore, if all the information is showed in thematic maps, the final waste management decisions can be made more efficiently. The main aim of this paper is to present a structured methodology that allows local authorities or private companies who deal with MSW to design its own MSW management plan depending on the available data. According to these data, this paper proposes two ways of action: a direct way when detailed data are available and an indirect way when there is a lack of data and it is necessary to take into account bibliographic data. In any case, the amount of information needed is considerable. This paper combines the planning methodology with the Geographic Information Systems to present the final results in thematic maps that make easier to interpret them. The proposed methodology is a previous useful tool to organize the MSW collection routes including the selective collection. To verify the methodology it has been successfully applied to a Spanish town. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Minimum-Energy Sub-Threshold Self-Timed Circuits: Design Methodology and a Case Study

    DEFF Research Database (Denmark)

    Akgun, Omer Can; Rodrigues, Joachim; Sparsø, Jens

    2010-01-01

    This paper addresses the design of self-timed energyminimum circuits, operating in the sub-VT domain. The paper presents a generic implementation template using bundled-data circuitry and current sensing completion detection. To support this, a fully-decoupled latch controller has been developed......, which integrates the current sensing circuitry. The paper outlines a corresponding design flow, which is based on contemporary synchronous EDA tools, and which transforms a synchronous design, into a corresponding self-timed circuit. The design flow and the current-sensing technique is validated...... by the implementation of an asynchronous version of a wavelet based event detector for cardiac pacemaker applications in a standard 65nm CMOS process. The chip has been fabricated and the area overhead due to power domain separation and completion detection circuitry is 13.6 %. The improvement in throughput due...

  1. Current state of methodological and decisions for radiation treatment of blood, its components and products

    Directory of Open Access Journals (Sweden)

    Gordeev A.V.

    2014-12-01

    Full Text Available This article presents currently used blood transfusion media — components and blood products, therapeutic effects, reactions and complications of blood transfusion, use of radiation treatment for blood transfusion fluids. There had been discussed in detail the practice of radiation processing of blood components and for the prevention of reaction "graft versus host" and studies of plasma radiation treatment for its infectious safety. There was presented the current state of techniques and technical solutions of radiation treatment of transfusion-transmissible environments. There were also considered an alternative to radiation treatment of blood.

  2. Equilibrium Design Based on Design Thinking Solving: An Integrated Multicriteria Decision-Making Methodology

    OpenAIRE

    Yi-Xiong Feng; Yi-Cong Gao; Xuan Song; Jian-Rong Tan

    2013-01-01

    A multicriteria decision-making model was proposed in order to acquire the optimum one among different product design schemes. VIKOR method was introduced to compute the ranking value of each scheme. A multiobjective optimization model for criteria weight was established. In this model, projection pursuit method was employed to identify a criteria weight set which could keep classification information of original schemes to the greatest extent, while PROMETHEE II was adopted to keep sorting i...

  3. Inductive Powering of Subcutaneous Stimulators: Key Parameters and Their Impact on the Design Methodology

    Science.gov (United States)

    Godfraind, Carmen; Debelle, Adrien; Lonys, Laurent; Acuña, Vicente; Doguet, Pascal; Nonclercq, Antoine

    2016-01-01

    Inductive powering of implantable medical devices involves numerous factors acting on the system efficiency and safety in adversarial ways. This paper lightens up their role and identifies a procedure enabling the system design. The latter enables the problem to be decoupled into four principal steps: the frequency choice, the magnetic link optimization, the secondary circuit and then finally the primary circuit designs. The methodology has been tested for the powering system of a device requirering a power of 300mW and implanted at a distance of 15 to 30mm from the outside power source. It allowed the identification of the most critical parameters. A satisfying efficiency of 34% was reached at 21mm and tend to validate the proposed design procedure. PMID:27478572

  4. Development of six sigma concurrent parameter and tolerance design method based on response surface methodology

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Using Response Surface Methodology (RSM), an optimizing model of concurrent parameter and tolerance design is proposed where response mean equals its target in the target being best. The optimizing function of the model is the sum of quality loss and tolerance cost subjecting to the variance confidence region of which six sigma capability can be assured. An example is illustrated in order to compare the differences between the developed model and the parameter design with minimum variance. The results show that the proposed method not only achieves robustness, but also greatly reduces cast. The objectives of high quality and low cost of product and process can be achieved simultaneously by the application of six sigma concurrent parameter and tolerance design.

  5. Design Methodology: ASICs with complex in-pixel processing for Pixel Detectors

    Energy Technology Data Exchange (ETDEWEB)

    Fahim, Farah [Fermilab

    2014-10-31

    The development of Application Specific Integrated Circuits (ASIC) for pixel detectors with complex in-pixel processing using Computer Aided Design (CAD) tools that are, themselves, mainly developed for the design of conventional digital circuits requires a specialized approach. Mixed signal pixels often require parasitically aware detailed analog front-ends and extremely compact digital back-ends with more than 1000 transistors in small areas below 100μm x 100μm. These pixels are tiled to create large arrays, which have the same clock distribution and data readout speed constraints as in, for example, micro-processors. The methodology uses a modified mixed-mode on-top digital implementation flow to not only harness the tool efficiency for timing and floor-planning but also to maintain designer control over compact parasitically aware layout.

  6. The Best Location for Speed Bump Installation Using Experimental Design Methodology

    Directory of Open Access Journals (Sweden)

    Alireza Khademi

    2013-12-01

    Full Text Available Speed bumps, as traffic calming devices, have been extensively used to reduce traffic speed on local streets. This study represents a unique application of experimental design methodology where the effects of some controllable factors in determining the best location for installing speed bumps before stop points (e.g. entry gates, road junctions were investigated. Through Classical Design of Experiments (DOE, the optimum location of the speed bump was obtained based on the graphical plots of the significant effects. The speed at the stop point was treated as the response and minimum speed is desirable. Design-Expert® software was used to evaluate and analyze the results obtained. The suggested mathematical model effectively explains the performance indicators within the ranges of the factors. The car speed is the most significant factor that affects the distance-time in comparison with other factors, which provides secondary contributions.

  7. A novel design methodology for low pass filter stage of a voltage source inverter

    Indian Academy of Sciences (India)

    ANIRBAN DE

    2016-05-01

    A low pass filter, an invariable constituent of a PWM based voltage source inverter, poses several challenges in its design. With a higher rating of the inverter, the volume as well as the cost of the components increases. With time, the filter design has evolved from the simpler first order filter to higher orders, the most popular being the third order LCL filters. Though the attenuation of high frequency components, offered by the higher order filters, has resulted in improved efficiency, the inherent instability of the higher order filter systemsrequires complex controls for proper functioning. Keeping this in mind, the paper describes the design methodology of a second order LC filter system based on certain performance indices that reflect the ratings of the components.

  8. A Model-Based Methodology for Integrated Design and Operation of Reactive Distillation Processes

    DEFF Research Database (Denmark)

    Mansouri, Seyed Soheil; Sales-Cruz, Mauricio; Huusom, Jakob Kjøbsted

    2015-01-01

    and resolved. A new approach isto tackle process intensification and controllability issues in an integrated manner, in the early stages of process design. This integrated and simultaneous synthesis approach provides optimal operation and moreefficient control of complex intensified systems that suffice...... bubble point algorithm is used to compute the reactive vapor-liquid equilibrium data set.The operation of the RDC at the highest driving force and other candidate points is compared through openloop and closed-loop analysis. By application of this methodology it is shown that designing the process atthe......Process intensification is a new approach that has the potential to improve existing processes as well as new designs of processes to achieve more profitable and sustainable production. However, many issues with respect to their implementation and operation is not clear; for example, the question...

  9. Enhancing the design and management of a local organic food supply chain with Soft Systems Methodology

    DEFF Research Database (Denmark)

    Tavella, Elena; Hjortsø, Carsten Nico Portefée

    2012-01-01

    Supply chain partners for local organic food face uncertainties such as poor collaboration and communication that cannot be reduced through the application of traditional supply chain design and management techniques. Such techniques are known to improve supply chain coordination, but they do...... not adequately consider major aspects of local organic food supply chains such as ethics, sustainability and human values. Supply chain design and management approaches suita-ble to small-scale, local organic food enterprises are lacking and need to be developed. The aim of this paper is to suggest Soft Systems...... Methodology (SSM) as a new and suitable ap-proach to design and manage local organic food supply chains. We illustrate how SSM can be used to reduce uncertainties within local organic food supply chains based on a German case. This illustration serves to identify the benefits of using SSM, compared with ad...

  10. A Methodology for the Design of Robotic Hands with Multiple Fingers

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Parada Puig

    2008-11-01

    Full Text Available This paper presents a methodology that has been applied for a design process of anthropomorphic hands with multiple fingers. Biomechanical characteristics of human hand have been analysed so that ergonomic and anthropometric aspects have been used as fundamental references for obtaining grasping mechanisms. A kinematic analysis has been proposed to define the requirements for designing grasping functions. Selection of materials and actuators has been discussed too. This topic has been based on previous experiences with prototypes that have been developed at the Laboratory of Robotics and Mechatronics (LARM of the University of Cassino. An example of the application of the proposed method has been presented for the design of a first prototype of LARM Hand.

  11. Inductive powering of subcutaneous stimulators: key parameters and their impact on the design methodology

    Directory of Open Access Journals (Sweden)

    Carmen Godfraind

    2016-06-01

    Full Text Available Inductive powering of implantable medical devices involves numerous factors acting on the system efficiency and safety in adversarial ways. This paper lightens up their role and identifies a procedure enabling the system design. The latter enables the problem to be decoupled into four principal steps: the frequency choice, the magnetic link optimization, the secondary circuit and then finally the primary circuit designs. The methodology has been tested for the powering system of a device requirering a power of 300mW and implanted at a distance of 15 to 30mm from the outside power source. It allowed the identification of the most critical parameters. A satisfying efficiency of 34% was reached at 21mm and tend to validate the proposed design procedure.

  12. Inductive Powering of Subcutaneous Stimulators: Key Parameters and Their Impact on the Design Methodology.

    Science.gov (United States)

    Godfraind, Carmen; Debelle, Adrien; Lonys, Laurent; Acuña, Vicente; Doguet, Pascal; Nonclercq, Antoine

    2016-06-13

    Inductive powering of implantable medical devices involves numerous factors acting on the system efficiency and safety in adversarial ways. This paper lightens up their role and identifies a procedure enabling the system design. The latter enables the problem to be decoupled into four principal steps: the frequency choice, the magnetic link optimization, the secondary circuit and then finally the primary circuit designs. The methodology has been tested for the powering system of a device requirering a power of 300mW and implanted at a distance of 15 to 30mm from the outside power source. It allowed the identification of the most critical parameters. A satisfying efficiency of 34% was reached at 21mm and tend to validate the proposed design procedure.

  13. Enhancing the design and management of a local organic food supply chain with Soft Systems Methodology

    DEFF Research Database (Denmark)

    Tavella, Elena; Hjortsø, Carsten Nico Portefée

    2012-01-01

    Supply chain partners for local organic food face uncertainties such as poor collaboration and communication that cannot be reduced through the application of traditional supply chain design and management techniques. Such techniques are known to improve supply chain coordination, but they do...... not adequately consider major aspects of local organic food supply chains such as ethics, sustainability and human values. Supply chain design and management approaches suita-ble to small-scale, local organic food enterprises are lacking and need to be developed. The aim of this paper is to suggest Soft Systems...... Methodology (SSM) as a new and suitable ap-proach to design and manage local organic food supply chains. We illustrate how SSM can be used to reduce uncertainties within local organic food supply chains based on a German case. This illustration serves to identify the benefits of using SSM, compared with ad...

  14. Preferences design information on the Internet. A new methodological proposal, carried out with the university students

    Directory of Open Access Journals (Sweden)

    Lic. Ana Isabel Bernal Triviño

    2008-01-01

    Full Text Available The purpose of this research is to learn about the preferences of young people on the design of information in the media on the Internet. The research takes the view that the sample of students is selected from eight designs real information online. First valued in a quantitative way and then justify their responses. The quantitative and qualitative methodology allows the results benefit from statistical rigor and greater depth. Due to the number of elements that make up the message visual information, this exploratory research pretending to know which are the most Initial findings have realized that the main preferences are linked to the presence of the media and typographical. With this data has begun a new investigation that materializa only in a quantitative way, the importance of the components of the design cited.

  15. System-Level Design Methodologies for Networked Multiprocessor Systems-on-Chip

    DEFF Research Database (Denmark)

    Virk, Kashif Munir

    2008-01-01

    of wireless integrated sensor networks which are an emerging class of networked embedded computer systems. The work described here demonstrates how to model multiprocessor systems-on-chip at the system level by abstracting away most of the lower-level details albeit retaining the parameters most relevant......The first part of the thesis presents an overview of the existing theories and practices of modeling and simulation of multiprocessor systems-on-chip. The systematic categorization of the plethora of existing programming models at various levels of abstraction is the main contribution here which...... is the first such attempt in the published literature. The second part of the thesis deals with the issues related to the development of system-level design methodologies for networked multiprocessor systems-on-chip at various levels of design abstraction with special focus on the modeling and design...

  16. A Human-Centered Design Methodology to Enhance the Usability, Human Factors, and User Experience of Connected Health Systems: A Three-Phase Methodology.

    Science.gov (United States)

    Harte, Richard; Glynn, Liam; Rodríguez-Molinero, Alejandro; Baker, Paul Ma; Scharf, Thomas; Quinlan, Leo R; ÓLaighin, Gearóid

    2017-03-16

    Design processes such as human-centered design, which involve the end user throughout the product development and testing process, can be crucial in ensuring that the product meets the needs and capabilities of the user, particularly in terms of safety and user experience. The structured and iterative nature of human-centered design can often present a challenge when design teams are faced with the necessary, rapid, product development life cycles associated with the competitive connected health industry. We wanted to derive a structured methodology that followed the principles of human-centered design that would allow designers and developers to ensure that the needs of the user are taken into account throughout the design process, while maintaining a rapid pace of development. In this paper, we present the methodology and its rationale before outlining how it was applied to assess and enhance the usability, human factors, and user experience of a connected health system known as the Wireless Insole for Independent and Safe Elderly Living (WIISEL) system, a system designed to continuously assess fall risk by measuring gait and balance parameters associated with fall risk. We derived a three-phase methodology. In Phase 1 we emphasized the construction of a use case document. This document can be used to detail the context of use of the system by utilizing storyboarding, paper prototypes, and mock-ups in conjunction with user interviews to gather insightful user feedback on different proposed concepts. In Phase 2 we emphasized the use of expert usability inspections such as heuristic evaluations and cognitive walkthroughs with small multidisciplinary groups to review the prototypes born out of the Phase 1 feedback. Finally, in Phase 3 we emphasized classical user testing with target end users, using various metrics to measure the user experience and improve the final prototypes. We report a successful implementation of the methodology for the design and development

  17. AGILE SOFTWARE DEVELOPMENT METHODOLOGIES: AN OVERVIEW OF THE CURRENT STATE OF RESEARCH

    Directory of Open Access Journals (Sweden)

    Naftanaila Ionel

    2009-05-01

    Full Text Available Under the current economic conditions many organizations strive to continue the trend towards adopting agile processes, in order to take advantage of the numerous benefits that these can offer. Those benefits include quicker return on investment, better s

  18. Design of Current steering DAC using 250nm CMOS Technology

    Directory of Open Access Journals (Sweden)

    Vineet Tiwari

    2012-06-01

    Full Text Available To build a digital to analog converter, that only receives digital signal that can only receives digital signal and produces only analog signal. A converter in which digital input signals are changed to essentially proportional analog signals. Abbreviated DAC a device for converting information in the forms of combination of discrete(usually binary states or signal to information in the form of combinations of discrete(usually binary states or signal to information in the form of value or magnitude of some characteristics of signal, in relation to standard or reference signal. Digital-toanalog (D/A converters (sometimes called DACs are used to present the results of digital computation, storage, or transmission, typically for graphical display or for the control of devices that operate with continuously varying quantities. D/A converter circuits are also used in the design of analog-to-digital converters that employ feedback techniques, such as successive-approximation and counter-comparator types. In such applications, the D/A converter may not necessarily appear as a separately identifiable entity. The fundamental circuit of most D/A converters involves a voltage or current reference; a resistive “ladder network” that derives weighted currents or voltages, usually as discrete fractions of the reference; and a set of switches, operated by the digital input, that determines which currents or voltages will be summed to constitute the output. The output of the D/A converter is proportional to the product of the digital input value and the reference. In many applications, the reference is fixed, and the output bears a fixed proportion to the digital input. In other applications, the reference, as well as the digital input, can vary; a D/A converter that is used in these applications is thus called a multiplying D/A converter. It is principally used for imparting a digitally controlled scale factor, or “gain,” to an analog input signal

  19. Current trends in health facility planning, design, and construction.

    Science.gov (United States)

    Beale, Craig; Kittredge, Frank D

    2014-01-01

    It is critical now more than ever for today's healthcare facilities to serve as more than just a backdrop to the care provided--they can, and should, be an integral part of that care. In addition to promoting efficacy, delighting the senses, and placing patients and families at ease, facilities need to be high-performing, sustainable, and healthy environments. Creating today's healthcare facilities requires breaking through barriers in unexpected ways, and it often requires looking outside the healthcare profession for guidance. In this article, we explore current trends in health facility planning, design, and construction. Our focus is on the buildings that serve as venues for the provision of healthcare services across the full continuum, from prevention to critical care. In particular, we discuss four current broad trends and conclude with thoughts on future developments.

  20. A system-of-systems modeling methodology for strategic general aviation design decision-making

    Science.gov (United States)

    Won, Henry Thome

    General aviation has long been studied as a means of providing an on-demand "personal air vehicle" that bypasses the traffic at major commercial hubs. This thesis continues this research through development of a system of systems modeling methodology applicable to the selection of synergistic product concepts, market segments, and business models. From the perspective of the conceptual design engineer, the design and selection of future general aviation aircraft is complicated by the definition of constraints and requirements, and the tradeoffs among performance and cost aspects. Qualitative problem definition methods have been utilized, although their accuracy in determining specific requirement and metric values is uncertain. In industry, customers are surveyed, and business plans are created through a lengthy, iterative process. In recent years, techniques have developed for predicting the characteristics of US travel demand based on travel mode attributes, such as door-to-door time and ticket price. As of yet, these models treat the contributing systems---aircraft manufacturers and service providers---as independently variable assumptions. In this research, a methodology is developed which seeks to build a strategic design decision making environment through the construction of a system of systems model. The demonstrated implementation brings together models of the aircraft and manufacturer, the service provider, and most importantly the travel demand. Thus represented is the behavior of the consumers and the reactive behavior of the suppliers---the manufacturers and transportation service providers---in a common modeling framework. The results indicate an ability to guide the design process---specifically the selection of design requirements---through the optimization of "capability" metrics. Additionally, results indicate the ability to find synergetic solutions, that is solutions in which two systems might collaborate to achieve a better result than acting

  1. LOADS INTERACTION DOMAINS METHODOLOGY FOR THE DESIGN OF STEEL GREENHOUSE STRUCTURES

    Directory of Open Access Journals (Sweden)

    Sergio Castellano

    2007-03-01

    Full Text Available Aim of this research is to develop a design methodology which correlates main structural design parameters, whose production is characterised by high levels of standardization, such as the height of gutter or the distance between frames, with actions on the greenhouse. The methodology, based on the use of charts and abacus, permits a clear and a direct interpretation of the structural response to design load combinations and allows the design of structural improvements with the aim of the optimization of the ratio benefits (structural strength/costs. The study of structural interaction domains allowed a clear and a direct interpretation of the structural response to design load combinations. The diagrams highlight not only if the structure fulfils the standard requirements but also the safety levels with respect to design load combinations and allow the structural designer how to operate in order to optimize the structural response with standard requirements achieving the best ratio benefits (structural safety/ costs. The methodology was developed basing on criteria assigned by EN13031 on two different kinds of greenhouse structures: an arched greenhouse with a film plastic covering and a duo pitched roof greenhouse cover with rigid plastic membranes. Structural interaction domains for arched greenhouse showed a better capability of the structure to resist to vertical loads then to horizontal one. Moreover, the climatic load distribution on the structure assigned by EN13031 is such that the combination of climatic actions is less dangerous for the structure then their individual application. Whilst, duo pitched roof steel greenhouse interaction domains, showed a better capability of the structure to resist to vertical loads then to horizontal one and that, in any case, the serviceability limit states analysis is more strict then the ULS one. The shape of structural domains highlighted that the combination of actions is more dangerous for the

  2. Ni-based Superalloy Development for VHTR - Methodology Using Design of Experiments and Thermodynamic Calculation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Woo; Kim, Dong Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    In this work, to develop novel structural materials for the IHX of a VHTR, a more systematic methodology using the design of experiments (DOE) and thermodynamic calculations was proposed. For 32 sets of designs of Ni-Cr-Co-Mo alloys with minor elements of W and Ta, the mass fraction of TCP phases and mechanical properties were calculated, and finally the chemical composition was optimized for further experimental studies by applying the proposed . The highly efficient generation of electricity and the production of massive hydrogen are possible using a very high temperature gas-cooled reactor (VHTR) among generation IV nuclear power plants. The structural material for an intermediate heat exchanger (IHX) among numerous components should be endurable at high temperature of up to 950 .deg. C during long-term operation. Impurities inevitably introduced in helium as a coolant facilitate the material degradation by corrosion at high temperature. This work is concerning a methodology of Ni-Cr-Co-Mo based superalloy developed for VHTR using the design of experiments (DOE) and thermodynamic calculationsmethodology.

  3. Methodology for the design of the method of siliceous sandstones operation using special software

    Directory of Open Access Journals (Sweden)

    Luis Ángel Lara-González

    2014-12-01

    Full Text Available The methodologies used for the design of the method of sandstones explotation by descending staggered banks using specialized software tools are reported. The data analyzed were collected in the field for the operating license 14816 in Melgar, Tolima. The characterization of the rock mass was held from physical and mechanical tests, performed on cylindrical test tubes in order to obtain the value of the maximum strenght and elastic modulus of the rock. The direction and dip of the sandstone package was rock. The direction and dip of the sandstone package was determined by using the stereographic projection whit DIPS®  software, and the safety factor of the slope was obtained with established banks whit SLIDE® . The slops are 8 meters high and 8 meters wide whit a tilt angle 60°, which generated a safety factor  of 2.1. The design  of the mining method was carried out with GEOVIA SURPAC® , at an early stage of development ascending to the level 11 of the exploitation, to then start mining in descending order to control the stabiLity of slopes. The results obtained allow a general methodology for the development of projects to optimize the process of evaluation and selection of mining method by using specialized design tools.

  4. Application of Box-Behnken design and response surface methodology for modeling of some Turkish coals

    Energy Technology Data Exchange (ETDEWEB)

    N. Aslan; Y. Cebeci [Cumhuriyet University, Sivas (Turkey). Mining Engineering Department

    2007-01-15

    The aim of our research was to apply Box-Behnken experimental design and response surface methodology for modeling of some Turkish coals. As a base for this study, standard Bond grindability tests were initially done and Bond work indexes (Wi) values were calculated for three Turkish coals. The Box-Behnken experimental design was used to provide data for modeling and the variables of model were Bond work index, grinding time and ball diameter of mill. Coal grinding tests were performed changing these three variables for three size fractions of coals (-3350 + 1700 {mu}m, -1700 + 710 {mu}m and -710 {mu}m). Using these sets of experimental data obtained by mathematical software package (MATLAB 7.1), mathematical models were then developed to show the effect of each parameter and their interactions on product 80% passing size (d{sub 80}). Predicted values of d80 obtained using model equations were in good agreement with the experimental values of d{sub 80} (R{sup 2} value of 0.96 for -3350 + 1700 {mu}m, R{sup 2} value of 0.98 for -1700 + 710 {mu}m and R{sup 2} value of 0.94 for -710 {mu}m). This study proved that Box-Behnken design and response surface methodology could efficiently be applied for modeling of grinding of some Turkish coals. 19 refs., 14 figs., 6 tabs.

  5. A SystemC-Based Design Methodology for Digital Signal Processing Systems

    Directory of Open Access Journals (Sweden)

    Christian Haubelt

    2007-03-01

    Full Text Available Digital signal processing algorithms are of big importance in many embedded systems. Due to complexity reasons and due to the restrictions imposed on the implementations, new design methodologies are needed. In this paper, we present a SystemC-based solution supporting automatic design space exploration, automatic performance evaluation, as well as automatic system generation for mixed hardware/software solutions mapped onto FPGA-based platforms. Our proposed hardware/software codesign approach is based on a SystemC-based library called SysteMoC that permits the expression of different models of computation well known in the domain of digital signal processing. It combines the advantages of executability and analyzability of many important models of computation that can be expressed in SysteMoC. We will use the example of an MPEG-4 decoder throughout this paper to introduce our novel methodology. Results from a five-dimensional design space exploration and from automatically mapping parts of the MPEG-4 decoder onto a Xilinx FPGA platform will demonstrate the effectiveness of our approach.

  6. Equilibrium Design Based on Design Thinking Solving: An Integrated Multicriteria Decision-Making Methodology

    Directory of Open Access Journals (Sweden)

    Yi-Xiong Feng

    2013-01-01

    Full Text Available A multicriteria decision-making model was proposed in order to acquire the optimum one among different product design schemes. VIKOR method was introduced to compute the ranking value of each scheme. A multiobjective optimization model for criteria weight was established. In this model, projection pursuit method was employed to identify a criteria weight set which could keep classification information of original schemes to the greatest extent, while PROMETHEE II was adopted to keep sorting information. Dominance based multiobjective simulated annealing algorithm (D-MOSA was introduced to solve the optimization model. Finally, an example was taken to demonstrate the feasibility and efficiency of this model.

  7. Superconducting fault-current limiter and inductor design

    Science.gov (United States)

    Rogers, J. D.; Boenig, H. J.; Chowdhuri, P.; Schermer, R. I.; Wollan, J. J.; Weldon, D. M.

    1982-11-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components, superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator, included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  8. Super conducting fault current limiter and inductor design

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.; Boenig, H.; Chowdhuri, P.; Schermer, R.; Weldon, D.; Wollan, J.

    1983-05-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components--superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator--included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  9. Superconducting fault-current limiter and inductor design

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.D.; Boenig, H.J.; Chowdhuri, P.; Schermer, R.I.; Wollan, J.J.; Weldon, D.M.

    1982-01-01

    A superconducting fault current limiter (SFCL) that uses a biased superconducting inductor in a diode or thyristor bridge circuit was analyzed for transmission systems in 69, 138, and 230 rms kV utility transmission systems. The limiter was evaluated for costs with all components - superconducting coil, diode and/or SCR power electronics, high voltage insulation, high voltage bushings and vapor cooled leads, dewar, and refrigerator - included. A design was undertaken for the superconducting cable and coils for both diode and SCR 69 kV limiter circuits.

  10. Application of Full Factorial Experimental Design and Response Surface Methodology for Chromite Beneficiation by Knelson Concentrator

    Directory of Open Access Journals (Sweden)

    Gul Akar Sen

    2016-01-01

    Full Text Available The present work is undertaken to determine the effect of operational variables, namely: feed rate, centrifugal force and fluidization water flow rate on the efficiency of Knelson concentrator for chromite ore beneficiation. A full factorial design with three factors at three levels and response surface methodology (RSM were applied for this purpose. The quadratic models were developed to predict the concentrate Cr2O3 grade and recovery as the process responses. The results suggest that all the variables affect the grade and recovery of the Cr2O3 concentrate to some degree. However, the fluidization water rate was found as the most effective parameter.

  11. Systematic Methodology for Design of Tailor-Made Blended Products: Fuels and Other Blended Products

    DEFF Research Database (Denmark)

    Yunus, Nor Alafiza Binti

    A tailor-made blended liquid product is defined as a formulation of various chemicals in the liquid state to obtain a liquid mixture with a specific set of desired characteristics and qualities. Examples of blended liquid products are synthetic fuels and lubricants. This type of products is very ...... methodology and tools was tested through two case studies. In the first case study, two different gasoline blend problems have been solved. In the second case study, four different lubricant design problems have been solved....

  12. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design

    Science.gov (United States)

    Rifai, Damhuji; Abdalla, Ahmed N.; Razali, Ramdan; Ali, Kharudin; Faraj, Moneer A.

    2017-01-01

    The use of the eddy current technique (ECT) for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT) use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR) sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM). The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient. PMID:28335399

  13. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design.

    Science.gov (United States)

    Rifai, Damhuji; Abdalla, Ahmed N; Razali, Ramdan; Ali, Kharudin; Faraj, Moneer A

    2017-03-13

    The use of the eddy current technique (ECT) for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT) use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR) sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM). The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient.

  14. An Eddy Current Testing Platform System for Pipe Defect Inspection Based on an Optimized Eddy Current Technique Probe Design

    Directory of Open Access Journals (Sweden)

    Damhuji Rifai

    2017-03-01

    Full Text Available The use of the eddy current technique (ECT for the non-destructive testing of conducting materials has become increasingly important in the past few years. The use of the non-destructive ECT plays a key role in the ensuring the safety and integrity of the large industrial structures such as oil and gas pipelines. This paper introduce a novel ECT probe design integrated with the distributed ECT inspection system (DSECT use for crack inspection on inner ferromagnetic pipes. The system consists of an array of giant magneto-resistive (GMR sensors, a pneumatic system, a rotating magnetic field excitation source and a host PC acting as the data analysis center. Probe design parameters, namely probe diameter, an excitation coil and the number of GMR sensors in the array sensor is optimized using numerical optimization based on the desirability approach. The main benefits of DSECT can be seen in terms of its modularity and flexibility for the use of different types of magnetic transducers/sensors, and signals of a different nature with either digital or analog outputs, making it suited for the ECT probe design using an array of GMR magnetic sensors. A real-time application of the DSECT distributed system for ECT inspection can be exploited for the inspection of 70 mm carbon steel pipe. In order to predict the axial and circumference defect detection, a mathematical model is developed based on the technique known as response surface methodology (RSM. The inspection results of a carbon steel pipe sample with artificial defects indicate that the system design is highly efficient.

  15. A fast transient response low dropout regulator with current control methodology

    Institute of Scientific and Technical Information of China (English)

    Ma Zhuo; Guo Yang; Duan Zhikui; Xie Lunguo; Chen Jihua; Yu Jinshan

    2011-01-01

    A transient performance optimized CCL-LDO regulator is proposed.In the CCL-LDO,the control method of the charge pump phase-locked loop is adopted.A current control loop has the feedback signal and reference current to be compared,and then a loop filter generates the gate voltage of the power MOSFET by integrating the error current.The CCL-LDO has the optimized damping coefficient and natural resonant frequency,while its output voltage can be sub-1-V and is not restricted by the reference voltage.With a 1μF decoupling capacitor,the experimental results based on a 0.13 μm CMOS process show that the output voltage is 1.0 V; when the workload changes from 100 μA to 100 mA transiently,the stable dropout is 4.25 mV,the settling time is 8.2 μs and the undershoot is 5.11 mV; when the workload changes from 1 00 mA to 100 μA transiently,the stable dropout is 4.25 mV,the settling time is 23.3 μs and the overshoot is 6.21 mV.The PSRR value is more than -95 dB.Most of the attributes of the CCL-LDO are improved rapidly with a FOM value of 0.0097.

  16. Current methodological approaches to determining the environmental competitiveness of products and manufacturers

    Directory of Open Access Journals (Sweden)

    S.K. Harichkov

    2013-09-01

    Full Text Available The aim of the article. The aim of the article is to develop methodological approaches to environmental assessments and enterprise competitiveness.The results of the analysis. Ensuring environmental competitiveness of producers and their products should be based on the creation of conditions for access to restricted environmentally friendly natural resources as factors of production. Environmentally friendly products may not be carried out under conditions of companies that pollute the environment. Environmental competitiveness of producers is provided based on two of its constituent factors. First it's impact on the environment: the value of economic - environmental damage inflicted terms of air emissions, discharges into water, waste disposal in water and land facilities, depletion of all natural resources in the process of extraction and application economic-environmental damage to the environment in the extraction of natural resources. The second factor is the production of environmentally viable products. Environmental competitiveness of goods is determined by environmental parameters as a commodity and its price are acceptable to consumers and appropriate to the effective demand for certain markets in certain time periods. An important condition for the formation of the competitive nature of the process is the qualitative state factors of production, which, in turn, depends on the environmental component condition, performance, environment, sustainability of natural resource base of the national economy.To environmental performance include:level (content contaminants in combustion engines of vehicles, equipment, machinery, facilities,the probability of harmful particles, gases emissions during storage, transportation, use or consumption of goods;radioactivity of the final product and others.Methods of assessing the environmental performance of the enterprise should consist of the following steps:Gathering and analyzing baseline information

  17. Review of current GPS methodologies for producing accurate time series and their error sources

    Science.gov (United States)

    He, Xiaoxing; Montillet, Jean-Philippe; Fernandes, Rui; Bos, Machiel; Yu, Kegen; Hua, Xianghong; Jiang, Weiping

    2017-05-01

    The Global Positioning System (GPS) is an important tool to observe and model geodynamic processes such as plate tectonics and post-glacial rebound. In the last three decades, GPS has seen tremendous advances in the precision of the measurements, which allow researchers to study geophysical signals through a careful analysis of daily time series of GPS receiver coordinates. However, the GPS observations contain errors and the time series can be described as the sum of a real signal and noise. The signal itself can again be divided into station displacements due to geophysical causes and to disturbing factors. Examples of the latter are errors in the realization and stability of the reference frame and corrections due to ionospheric and tropospheric delays and GPS satellite orbit errors. There is an increasing demand on detecting millimeter to sub-millimeter level ground displacement signals in order to further understand regional scale geodetic phenomena hence requiring further improvements in the sensitivity of the GPS solutions. This paper provides a review spanning over 25 years of advances in processing strategies, error mitigation methods and noise modeling for the processing and analysis of GPS daily position time series. The processing of the observations is described step-by-step and mainly with three different strategies in order to explain the weaknesses and strengths of the existing methodologies. In particular, we focus on the choice of the stochastic model in the GPS time series, which directly affects the estimation of the functional model including, for example, tectonic rates, seasonal signals and co-seismic offsets. Moreover, the geodetic community continues to develop computational methods to fully automatize all phases from analysis of GPS time series. This idea is greatly motivated by the large number of GPS receivers installed around the world for diverse applications ranging from surveying small deformations of civil engineering structures (e

  18. Methodology of Compliant Mechanisms and its Current Developments in Applications: A Review

    Directory of Open Access Journals (Sweden)

    Solehuddin Shuib

    2007-01-01

    Full Text Available Traditional rigid-body mechanisms consist of a number of components to implement their functions. Therefore they face problems such as backlash, wear, increase in part-count, weight, assembly cost and time, regular maintenance. Reducing these problems will help in increasing mechanism performance and cost reduction. Recently, there are several examples of compliant mechanisms that have been designed and widely used in various fields such as for adaptive structures, biomedical, hand-held tools, components in transportations, MEMS and robotics. However, the largest challenge was relative difficulty in analyzing and designing compliant mechanisms. Two approaches known in the literature for the systematic synthesis of compliant mechanisms are the kinematics-based approach and the structural optimisation based approach.

  19. Rapid and reliable seismic source characterization in earthquake early warning systems: current methodologies, results, and new perspectives

    Science.gov (United States)

    Colombelli, Simona; Zollo, Aldo

    2016-10-01

    In the present paper, we provided a review of the main principles and methodologies on which the current earthquake early warning systems are grounded and will also provide a perspective view for next future developments and improvements. First, we introduce the standard methodologies for the source characterization in earthquake early warning, with a special focus on the real-time earthquake magnitude determination. We discuss the suitability of existent methodologies and empirical regression laws for very large events. We then present the different approaches for the rapid prediction of the ground shaking and of the potential damaged zone, both based on traditional seismic data and on the use of continuous GPS data. Finally, the last part of the paper provides the perspective view toward a next generation of early warning systems, linking new research achievements about the earthquake rupture nucleation and the development of new methods/technologies aimed at a fast and high-resolution, real-time modeling of the ongoing source process and accurate prediction of the quake shaking at the regional and local scale.

  20. Shape slack: a design-manufacturing co-optimization methodology using tolerance information

    Science.gov (United States)

    Banerjee, Shayak; Agarwal, Kanak B.; Nassif, Sani; Orshansky, Michael

    2013-01-01

    The move to low-k1 lithography makes it increasingly difficult to print feature sizes that are a small fraction of the wavelength of light. With further delay in the delivery of extreme ultraviolet lithography, these difficulties will motivate the research community to explore increasingly broad solutions. We propose that there is significant research potential in studying the essential premise of the design/manufacturing handoff paradigm. Today this premise revolves around design rules that define what implementations are legal, and raw shapes, which define design intent, and are treated as a fixed requirement for lithography. In reality, layout features may vary within certain tolerances without violating any design constraints. The knowledge of such tolerances can help improve the manufacturability of layout features while still meeting design requirements. We propose a methodology to convert electrical slack in a design to shape slack or tolerances on individual layout shapes. We show how this can be done for two important implementation fabrics: (a) cell-library-based digital logic and (b) static random access memory. We further develop a tolerance-driven optical proximity correction algorithm that utilizes this shape slack information during mask preparation to ensure that all features prints within their shape slacks in presence of lithographic process variations. Experiments on 45 nm silicon on insulator cells using accurate process models show that this approach reduces postlithography delay errors by 50%, and layout hotspots by 47% compared to conventional methods.

  1. Development of design methodology for communication network in nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Hoon; Seong, Seung Hwan; Jang Gwi Sook; Koo, In Soo; Lee Soon Sung

    1996-06-01

    This report describe the design methodology of communication network (CN) in nuclear power plants (NPPs). The construction procedure for the NPP CN consists of 4 phases, in study and review phase, design concepts and goals are established through technical review, collection of background information and feasibility study. In design phase, all of design activities such as extraction of requirements, communication modelling, overall and detail architecture design are performed. Implementation and test phase includes the manufacturing, installation and testing of hardware and software. In operation phase, CN construction is finalized through the evaluation and correction during operation. The requirements of CN consist of general requirements such as function, structure, reliability, standardization and detail requirements related with protocol, media, error, performance and etc. CN design also should follow the safety-related requirements such as isolation, redundancy, reliability and verify these requirements. For the selection of each technical element form commercial CN, the evaluation and selection elements are extracted from reliability, performance, operating factors and the required-level which classified into essential, primary, preference, recommendation should be assigned to each element. This report will be used as a technical reference for the CN implementation in NPP. (author). 3 tabs., 5 figs., 25 refs.

  2. Design of a Programmable Gain, Temperature Compensated Current-Input Current-Output CMOS Logarithmic Amplifier.

    Science.gov (United States)

    Ming Gu; Chakrabartty, Shantanu

    2014-06-01

    This paper presents the design of a programmable gain, temperature compensated, current-mode CMOS logarithmic amplifier that can be used for biomedical signal processing. Unlike conventional logarithmic amplifiers that use a transimpedance technique to generate a voltage signal as a logarithmic function of the input current, the proposed approach directly produces a current output as a logarithmic function of the input current. Also, unlike a conventional transimpedance amplifier the gain of the proposed logarithmic amplifier can be programmed using floating-gate trimming circuits. The synthesis of the proposed circuit is based on the Hart's extended translinear principle which involves embedding a floating-voltage source and a linear resistive element within a translinear loop. Temperature compensation is then achieved using a translinear-based resistive cancelation technique. Measured results from prototypes fabricated in a 0.5 μm CMOS process show that the amplifier has an input dynamic range of 120 dB and a temperature sensitivity of 230 ppm/°C (27 °C- 57°C), while consuming less than 100 nW of power.

  3. Design and optimization of a flexible arrayed eddy current sensor

    Science.gov (United States)

    Sun, Zhenguo; Cai, Dong; Zou, Cheng; Zhang, Wenzeng; Chen, Qiang

    2017-04-01

    The inspection of the hollow axle inner surfaces is a key process to guarantee the safety of high-speed trains. A novel flexible arrayed eddy current sensor was developed to improve the reliability of the non-destructive testing of the hollow axle inner surfaces, whose main innovative aspect was the new design of excitation/sensing traces to achieve a differential and arrayed configuration. Only two independent excitation traces were used in the sensor to induce eddy currents, which can be detected by 16 differential sensing elements. The lift-off effects and the influence of the excitation frequency and geometrical parameters of the proposed sensor was investigated and presented in this paper. Finite element models were built to analyze the effects of each parameter on the sensor response amplitude. Experimental validations were conducted using a representative set of sensors. Results from experiments and simulations were consistent with each other, which showed that the sensor design can substantially suppress the lift-off effects and modifications of the studied parameters can substantially improve the sensor performance.

  4. Application of the MIAS methodology in design of the data acquisition system for wastewater treatment plant

    Science.gov (United States)

    Ćwikła, G.; Krenczyk, D.; Kampa, A.; Gołda, G.

    2015-11-01

    This paper presents application of MIAS (Manufacturing Information Acquisition System) methodology to develop customized data acquisition system supporting management of the Central Wastewater Treatment Plant (CWWTP) in Gliwice, Poland, being example of production systems leading continuous flow, automated production processes. Access to current data on the state of production system is a key to efficient management of a company, allowing fast reaction or even anticipation of future problems with equipment and reduction of waste. Overview of both analysis and synthesis of organisational solutions, data sources, data pre-processing and communication interfaces, realised according to proposed MIAS methodology, had been presented. The stage of analysis covered i.e.: organisational structure of the company, IT systems used in the company, specifics of technological processes, machines and equipment, structure of control systems, assignments of crew members, materials used in the technological processes. This paper also presents results of the stage of synthesis of technical and organisational solutions of MIAS for CWWTP, including proposed solutions covering MIAS architecture and connections with other IT systems, data sources in production system that are currently available and newly created, data preprocessing procedures, and necessary communication interfaces.

  5. Human factors analysis and design methods for nuclear waste retrieval systems. Human factors design methodology and integration plan

    Energy Technology Data Exchange (ETDEWEB)

    Casey, S.M.

    1980-06-01

    The purpose of this document is to provide an overview of the recommended activities and methods to be employed by a team of human factors engineers during the development of a nuclear waste retrieval system. This system, as it is presently conceptualized, is intended to be used for the removal of storage canisters (each canister containing a spent fuel rod assembly) located in an underground salt bed depository. This document, and the others in this series, have been developed for the purpose of implementing human factors engineering principles during the design and construction of the retrieval system facilities and equipment. The methodology presented has been structured around a basic systems development effort involving preliminary development, equipment development, personnel subsystem development, and operational test and evaluation. Within each of these phases, the recommended activities of the human engineering team have been stated, along with descriptions of the human factors engineering design techniques applicable to the specific design issues. Explicit examples of how the techniques might be used in the analysis of human tasks and equipment required in the removal of spent fuel canisters have been provided. Only those techniques having possible relevance to the design of the waste retrieval system have been reviewed. This document is intended to provide the framework for integrating human engineering with the rest of the system development effort. The activities and methodologies reviewed in this document have been discussed in the general order in which they will occur, although the time frame (the total duration of the development program in years and months) in which they should be performed has not been discussed.

  6. Combining qualitative and quantitative research within mixed method research designs: a methodological review.

    Science.gov (United States)

    Östlund, Ulrika; Kidd, Lisa; Wengström, Yvonne; Rowa-Dewar, Neneh

    2011-03-01

    It has been argued that mixed methods research can be useful in nursing and health science because of the complexity of the phenomena studied. However, the integration of qualitative and quantitative approaches continues to be one of much debate and there is a need for a rigorous framework for designing and interpreting mixed methods research. This paper explores the analytical approaches (i.e. parallel, concurrent or sequential) used in mixed methods studies within healthcare and exemplifies the use of triangulation as a methodological metaphor for drawing inferences from qualitative and quantitative findings originating from such analyses. This review of the literature used systematic principles in searching CINAHL, Medline and PsycINFO for healthcare research studies which employed a mixed methods approach and were published in the English language between January 1999 and September 2009. In total, 168 studies were included in the results. Most studies originated in the United States of America (USA), the United Kingdom (UK) and Canada. The analytic approach most widely used was parallel data analysis. A number of studies used sequential data analysis; far fewer studies employed concurrent data analysis. Very few of these studies clearly articulated the purpose for using a mixed methods design. The use of the methodological metaphor of triangulation on convergent, complementary, and divergent results from mixed methods studies is exemplified and an example of developing theory from such data is provided. A trend for conducting parallel data analysis on quantitative and qualitative data in mixed methods healthcare research has been identified in the studies included in this review. Using triangulation as a methodological metaphor can facilitate the integration of qualitative and quantitative findings, help researchers to clarify their theoretical propositions and the basis of their results. This can offer a better understanding of the links between theory and

  7. Design methodology for a special single winding based bearingless switched reluctance motor

    Directory of Open Access Journals (Sweden)

    Madhurjya Dev Choudhury

    2017-06-01

    Full Text Available Bearingless switched reluctance motors (BSRMs have both magnetic bearing as well as conventional motor characteristics which make them suitable for diverse industrial applications. This study proposes a design methodology for a BSRM in order to calculate the appropriate geometrical dimensions essential for realising a minimum levitation force at every orientation of rotor. It is based on the stator–rotor overlap angle and helps in reducing the complexities associated with the self-bearing operation of a switched reluctance motor (SRM. Different from a conventional SRM, the motor under study deploys a special single set parallel winding scheme for simultaneous production of torque as well as radial force. An analytical model incorporating this single set winding is developed for calculating the torque and the radial force. The proposed bearingless design is verified by developing a two-dimensional finite-element model of a 12/8 SRM in ANSYS Maxwell.

  8. Vision-based methodology for collaborative management of qualitative criteria in design

    DEFF Research Database (Denmark)

    Tollestrup, Christian

    2006-01-01

    A Vision-based methodology is proposed as part of the management of qualitative criteria for design in early phases of the product development process for team based organisations. Focusing on abstract values and qualities for the product establishes a shared vision for the product amongst team...... members. Two anchor points are used for representing these values and qualities, the Value Mission and the Interaction Vision. Qualifying the meaning of these words trough triangulation of methods develops a shared mental model within the team. The composition of keywords within the Vision and Mission...... establishes a field of tension that summarises the abstract criteria and pinpoints the desired uniqueness of the product. The Interaction Vision allows the team members to design the behaviour of the product without deciding on physical features, thus focusing on the cognitive aspects of the product...

  9. Application of Adjoint Methodology to Supersonic Aircraft Design Using Reversed Equivalent Areas

    Science.gov (United States)

    Rallabhandi, Sriram K.

    2013-01-01

    This paper presents an approach to shape an aircraft to equivalent area based objectives using the discrete adjoint approach. Equivalent areas can be obtained either using reversed augmented Burgers equation or direct conversion of off-body pressures into equivalent area. Formal coupling with CFD allows computation of sensitivities of equivalent area objectives with respect to aircraft shape parameters. The exactness of the adjoint sensitivities is verified against derivatives obtained using the complex step approach. This methodology has the benefit of using designer-friendly equivalent areas in the shape design of low-boom aircraft. Shape optimization results with equivalent area cost functionals are discussed and further refined using ground loudness based objectives.

  10. Methodology for assessing the impacts of alternative rate designs on industrial energy use. Draft report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-11

    A task was undertaken to develop a method for analyzing industrial user responses to alternative rate designs. The method described considers the fuel switching and conservation responses of industrial users and the impact to a hypothetical utility regarding revenue stability, annual gas demand, and seasonal fluctuations. Twenty-seven hypothetical industrial plant types have been specified. For each combustor in the plant, the fuel consumption by season, initial fuel type, fuel switching costs, conservation costs, and amount of fuel conservable is provided. The decision making takes place at the plant level and is aggregated to determine the impact to the utility. Section 2 discusses the factors affecting an industrial user's response to alternative rate designs. Section 3 describes the methodology, includes an overview of the model and an example industrial user's response to a set of fuel prices. The data describing the 27 hypothetical firms is in an appendix.

  11. A hybrid design methodology for structuring an Integrated Environmental Management System (IEMS) for shipping business.

    Science.gov (United States)

    Celik, Metin

    2009-03-01

    The International Safety Management (ISM) Code defines a broad framework for the safe management and operation of merchant ships, maintaining high standards of safety and environmental protection. On the other hand, ISO 14001:2004 provides a generic, worldwide environmental management standard that has been utilized by several industries. Both the ISM Code and ISO 14001:2004 have the practical goal of establishing a sustainable Integrated Environmental Management System (IEMS) for shipping businesses. This paper presents a hybrid design methodology that shows how requirements from both standards can be combined into a single execution scheme. Specifically, the Analytic Hierarchy Process (AHP) and Fuzzy Axiomatic Design (FAD) are used to structure an IEMS for ship management companies. This research provides decision aid to maritime executives in order to enhance the environmental performance in the shipping industry.

  12. Nurse forecasting in Europe (RN4CAST): Rationale, design and methodology

    OpenAIRE

    Scott, Anne

    2011-01-01

    Background: Current human resources planning models in nursing are unreliable and ineffective as they consider volumes, but ignore effects on quality in patient care. The project RN4CAST aims innovative forecasting methods by addressing not only volumes, but quality of nursing staff as well as quality of patient care. Methods/Design: A multi-country, multilevel cross-sectional design is used to obtain important unmeasured factors in forecasting models including how features of hospital wo...

  13. An overview of the current methodologies used for evaluation of anti-fertility agents

    Directory of Open Access Journals (Sweden)

    Manisha Shah

    2016-05-01

    Full Text Available Discoveries in the past two decades have continued to improve our understanding of the mechanism of fertilization and animal models have played a significant role to define the basic mechanism of anti-fertility agents. In vivo models have been developed in the past years to study the anti-fertility agents. Methods that are used in anti-fertility study can be categorized into method including estimation of sex hormones, assessment of sperm motility and count, assessment of sperm viability and morphology, mating trial test body, sex organ weights, abortifacient activity, post-coital anti-fertility activity, effect on estrous cycle, anti-estrogenic activity, anti-gonadotrophic effect and quantification of fructose in seminal vesicle, histopathology, and biochemical methods. This review aims to highlight some of the new and currently, used experimental models that are used for the evaluation of anti-fertility agents.

  14. High-resolution simulations for Vietnam - methodology and evaluation of current climate

    Science.gov (United States)

    Katzfey, Jack; Nguyen, Kim; McGregor, John; Hoffmann, Peter; Ramasamy, Suppiah; Nguyen, Hiep Van; Khiem, Mai Van; Nguyen, Thang Van; Truong, Kien Ba; Vu, Thang Van; Nguyen, Hien Thuan; Thuc, Tran; Phong, Doan Ha; Nguyen, Bang Thanh; Phan-Van, Tan; Nguyen-Quang, Trung; Ngo-Duc, Thanh; Trinh-Tuan, Long

    2016-05-01

    To assist the government of Vietnam in its efforts to better understand the impacts of climate change and prioritise its adaptation measures, dynamically downscaled climate change projections were produced across Vietnam. Two Regional Climate Models (RCMs) were used: CSIRO's variable-resolution Conformal-Cubic Atmospheric Model (CCAM) and the limited-area model Regional Climate Model system version 4.2 (RegCM4.2). First, global CCAM simulations were completed using bias- and variance-corrected sea surface temperatures as well as sea ice concentrations from six Coupled Model Intercomparison Project Phase 5 (CMIP5) global climate models. This approach is different from other downscaling approaches as it does not use any atmospheric fields from the GCMs. The global CCAM simulations were then further downscaled to 10 km using CCAM and to 20 km using RegCM4.2. Evaluations of temperature and precipitation for the current climate (1980-2000) were completed using station data as well as various gridded observational datasets. The RCMs were able to reproduce reasonably well most of the important characteristics of observed spatial patterns and annual cycles of temperature. Average and minimum temperatures were well simulated (biases generally less than 1oC), while maximum temperatures had biases of around 1oC. For precipitation, although the RCMs captured the annual cycle, RegCM4.2 was too dry in Oct.-Nov. (-60% bias), while CCAM was too wet in Dec.- Mar. (130% bias). Both models were too dry in summer and too wet in winter (especially in northern Vietnam). The ability of the ensemble simulations to capture current climate increases confidence in the simulations of future climate.

  15. Methodology and planning for a microprocessor-oriented real time controller design automation system

    Energy Technology Data Exchange (ETDEWEB)

    Matelan, M.N.; Smith, R.J. II

    1976-11-04

    A methodology for reducing the complexity of designing dedicated real-time control systems is developed. It is shown that three areas are amenable to automation: the selection and configuration of hardware, the production of software, and the adaptation of a monitor to maintain real-time integrity of the entire system. The concept of hardware binding is introduced, and it is shown that delaying the point in the design cycle where hardware is functionally bound allows a new approach to machine independence. Concepts which allow expression of repetitive control situations are described, and a realization-independent language (CSDL), based on these concepts, is defined. Methods for automatically selecting a time-wise correct monitor are classified, and techniques for specifying the realization capabilities of digital processors are discussed. These concepts and techniques are brought together in a design automation system for the production of a complete controller design from a behavioral description. An example description is traced through the CSD System; a software listing and hardware configuration document for an actual microprocessor (the Intel 8080) is produced. This research provides a structured description of the control system design process, and allows a unified perspective in the realization of controllers for applications previously considered to be unrelated. The concepts developed define a new direction in the production of real-time control systems. 9 figures, 4 tables.

  16. A robust rotorcraft flight control system design methodology utilizing quantitative feedback theory

    Science.gov (United States)

    Gorder, Peter James

    1993-01-01

    Rotorcraft flight control systems present design challenges which often exceed those associated with fixed-wing aircraft. First, large variations in the response characteristics of the rotorcraft result from the wide range of airspeeds of typical operation (hover to over 100 kts). Second, the assumption of vehicle rigidity often employed in the design of fixed-wing flight control systems is rarely justified in rotorcraft where rotor degrees of freedom can have a significant impact on the system performance and stability. This research was intended to develop a methodology for the design of robust rotorcraft flight control systems. Quantitative Feedback Theory (QFT) was chosen as the basis for the investigation. Quantitative Feedback Theory is a technique which accounts for variability in the dynamic response of the controlled element in the design robust control systems. It was developed to address a Multiple-Input Single-Output (MISO) design problem, and utilizes two degrees of freedom to satisfy the design criteria. Two techniques were examined for extending the QFT MISO technique to the design of a Multiple-Input-Multiple-Output (MIMO) flight control system (FCS) for a UH-60 Black Hawk Helicopter. In the first, a set of MISO systems, mathematically equivalent to the MIMO system, was determined. QFT was applied to each member of the set simultaneously. In the second, the same set of equivalent MISO systems were analyzed sequentially, with closed loop response information from each loop utilized in subsequent MISO designs. The results of each technique were compared, and the advantages of the second, termed Sequential Loop Closure, were clearly evident.

  17. Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

    Directory of Open Access Journals (Sweden)

    Brad B Swelstad

    2009-12-01

    Full Text Available Brad B Swelstad, Candace L KerrInstitute for Cell Engineering, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MA, USAAbstract: Pluripotent stem cells have been derived from various embryonic, fetal and adult sources. Embryonic stem cells (ESCs and parthenogenic ESCs (pESCs are derived from the embryo proper while embryonic germ cells (EGCs, embryonal carcinoma cells (ECCs, and germ-line stem cells (GSC are produced from germ cells. ECCs were the first pluripotent stem cell lines established from adult testicular tumors while EGCs are generated in vitro from primordial germ cells (PGCs isolated in late embryonic development. More recently, studies have also demonstrated the ability to produce GSCs from adult germ cells, known as spermatogonial stem cells. Unlike ECCs, the source of GSCs are normal, non-cancerous adult tissue. The study of these unique cell lines has provided information that has led to the ability to reprogram somatic cells into an ESC-like state. These cells, called induced pluripotent stem cells (iPSCs, have been derived from a number of human fetal and adult origins. With the promises pluripotent stem cells bring to cell-based therapies there remain several considerations that need to be carefully studied prior to their clinical use. Many of these issues involve understanding key factors regulating their generation, including those which define pluripotency. In this regard, the following article discusses critical aspects of pluripotent stem cell derivation and current issues about their therapeutic potential.Keywords: pluripotency, stem cells, derivation, human

  18. Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations.

    Science.gov (United States)

    Swelstad, Brad B; Kerr, Candace L

    2009-12-22

    Pluripotent stem cells have been derived from various embryonic, fetal and adult sources. Embryonic stem cells (ESCs) and parthenogenic ESCs (pESCs) are derived from the embryo proper while embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and germ-line stem cells (GSC) are produced from germ cells. ECCs were the first pluripotent stem cell lines established from adult testicular tumors while EGCs are generated in vitro from primordial germ cells (PGCs) isolated in late embryonic development. More recently, studies have also demonstrated the ability to produce GSCs from adult germ cells, known as spermatogonial stem cells. Unlike ECCs, the source of GSCs are normal, non-cancerous adult tissue. The study of these unique cell lines has provided information that has led to the ability to reprogram somatic cells into an ESC-like state. These cells, called induced pluripotent stem cells (iPSCs), have been derived from a number of human fetal and adult origins. With the promises pluripotent stem cells bring to cell-based therapies there remain several considerations that need to be carefully studied prior to their clinical use. Many of these issues involve understanding key factors regulating their generation, including those which define pluripotency. In this regard, the following article discusses critical aspects of pluripotent stem cell derivation and current issues about their therapeutic potential.

  19. An overview of the current methodologies used for evaluation of aphrodisiac agents

    Institute of Scientific and Technical Information of China (English)

    Ramandeep Singh; Ashraf Ali; G Jeyabalan; Alok Semwal; Jaikishan

    2013-01-01

    Discoveries in the past two decades have continued to improve our understanding of the pathophysiology of erectile dysfunction disease and animal models have played a significant role to define the basic mechanisms of erectile dysfunction treatment.Bothin vitroandin vivomodels have been developed in the past years to study the aphrodisiac agents.Methods that are used in aphrodisiac study can be categorized into physical methods including male sexual behavior (mount frequency, mount latency, intromission frequency, intromission latency, ejaculation frequency, post-ejaculatory interval, couplatory rate, index of libido, computed male sexual behavior parameter), pendiculation study, orientation behavior, determination of hesitation time & attraction towards female, test of potency, test for libido, penile microcirculation study, Intracavernous pressure study and biochemical methods, histopathology, sperm count,Fructose content in seminal vesicles, sperm preservation, organ weight, hormonal determination, assay of nitric oxide synthase, In vitro nitric oxide release & androgen receptor protein.This review aims to highlight some of the new and currently used experimental models that are used for the evaluation of aphrodisiac agents.

  20. DEVELOPMENT OF METHODOLOGY FOR DESIGNING TESTABLE COMPONENT STRUCTURE OF DISCIPLINARY COMPETENCE

    Directory of Open Access Journals (Sweden)

    Vladimir I. Freyman

    2014-01-01

    Full Text Available The aim of the study is to present new methods of quality results assessment of the education corresponding to requirements of Federal State Educational Standards (FSES of the Third Generation developed for the higher school. The urgency of search of adequate tools for quality competency measurement and its elements formed in the course of experts’ preparation are specified. Methods. It is necessary to consider interference of competency components such as knowledge, abilities, possession in order to make procedures of assessment of students’ achievements within the limits of separate discipline or curriculum section more convenient, effective and exact. While modeling of component structure of the disciplinary competence the testable design of components is used; the approach borrowed from technical diagnostics. Results. The research outcomes include the definition and analysis of general iterative methodology for testable designing component structure of the disciplinary competence. Application of the proposed methodology is illustrated as the example of an abstract academic discipline with specified data and index of labour requirement. Methodology restrictions are noted; practical recommendations are given. Scientific novelty. Basic data and a detailed step-by-step implementation phase of the proposed common iterative approach to the development of disciplinary competence testable component structure are considered. Tests and diagnostic tables for different options of designing are proposed. Practical significance. The research findings can help promoting learning efficiency increase, a choice of adequate control devices, accuracy of assessment, and also efficient use of personnel, temporal and material resources of higher education institutions. Proposed algorithms, methods and approaches to procedure of control results organization and realization of developed competences and its components can be used as methodical base while

  1. Design of a CMOS temperature sensor with current output

    NARCIS (Netherlands)

    Kolling, A.; Kölling, Arjan; Bak, Frans; Bergveld, Piet; Seevinck, E.; Seevinck, Evert

    1990-01-01

    In this paper a CMOS temperature-to-current converter is presented of which the output current is the difference between a PTC current and an NTC current. The PTC current is derived from a PTAT cell, while the NTC current is derived from a threshold voltage reference source. It is shown that this

  2. The Prekindergarten Age-Cutoff Regression-Discontinuity Design: Methodological Issues and Implications for Application

    Science.gov (United States)

    Lipsey, Mark W.; Weiland, Christina; Yoshikawa, Hirokazu; Wilson, Sandra Jo; Hofer, Kerry G.

    2015-01-01

    Much of the currently available evidence on the causal effects of public prekindergarten programs on school readiness outcomes comes from studies that use a regression-discontinuity design (RDD) with the age cutoff to enter a program in a given year as the basis for assignment to treatment and control conditions. Because the RDD has high internal…

  3. Multi-Threshold NULL Convention Logic (MTNCL: An Ultra-Low Power Asynchronous Circuit Design Methodology

    Directory of Open Access Journals (Sweden)

    Liang Zhou

    2015-05-01

    Full Text Available This paper develops an ultra-low power asynchronous circuit design methodology, called Multi-Threshold NULL Convention Logic (MTNCL, also known as Sleep Convention Logic (SCL, which combines Multi-Threshold CMOS (MTCMOS with NULL Convention Logic (NCL, to yield significant power reduction without any of the drawbacks of applying MTCMOS to synchronous circuits. In contrast to other power reduction techniques that usually result in large area overhead, MTNCL circuits are actually smaller than their original NCL versions. MTNCL utilizes high-Vt transistors to gate power and ground of a low-Vt logic block to provide for both fast switching and very low leakage power when idle. To demonstrate the advantages of MTNCL, a number of 32-bit IEEE single-precision floating-point co-processors were designed for comparison using the 1.2 V IBM 8RF-LM 130 nm CMOS process: original NCL, MTNCL with just combinational logic (C/L slept, Bit-Wise MTNCL (BWMTNCL, MTNCL with C/L and completion logic slept, MTNCL with C/L, completion logic, and registers slept, MTNCL with Safe Sleep architecture, and synchronous MTCMOS. These designs are compared in terms of throughput, area, dynamic energy, and idle power, showing the tradeoffs between the various MTNCL architectures, and that the best MTNCL design is much better than the original NCL design in all aspects, and much better than the synchronous MTCMOS design in terms of area, energy per operation, and idle power, although the synchronous design can operate faster.

  4. Assessment of biodistribution using mesenchymal stromal cells: Algorithm for study design and challenges in detection methodologies.

    Science.gov (United States)

    Reyes, Blanca; Coca, Maria Isabel; Codinach, Margarita; López-Lucas, María Dolores; Del Mazo-Barbara, Anna; Caminal, Marta; Oliver-Vila, Irene; Cabañas, Valentín; Lope-Piedrafita, Silvia; García-López, Joan; Moraleda, José M; Fontecha, Cesar G; Vives, Joaquim

    2017-09-01

    Biodistribution of candidate cell-based therapeutics is a critical safety concern that must be addressed in the preclinical development program. We aimed to design a decision tree based on a series of studies included in actual dossiers approved by competent regulatory authorities, noting that the design, execution and interpretation of pharmacokinetics studies using this type of therapy is not straightforward and presents a challenge for both developers and regulators. Eight studies were evaluated for the definition of a decision tree, in which mesenchymal stromal cells (MSCs) were administered to mouse, rat and sheep models using diverse routes (local or systemic), cell labeling (chemical or genetic) and detection methodologies (polymerase chain reaction [PCR], immunohistochemistry [IHC], fluorescence bioimaging, and magnetic resonance imaging [MRI]). Moreover, labeling and detection methodologies were compared in terms of cost, throughput, speed, sensitivity and specificity. A decision tree was defined based on the model chosen: (i) small immunodeficient animals receiving heterologous MSC products for assessing biodistribution and other safety aspects and (ii) large animals receiving homologous labeled products; this contributed to gathering data not only on biodistribution but also on pharmacodynamics. PCR emerged as the most convenient technique despite the loss of spatial information on cell distribution that can be further assessed by IHC. This work contributes to the standardization in the design of biodistribution studies by improving methods for accurate assessment of safety. The evaluation of different animal models and screening of target organs through a combination of techniques is a cost-effective and timely strategy. Copyright © 2017 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  5. A Design Heritage-Based Forecasting Methodology for Risk Informed Management of Advanced Systems

    Science.gov (United States)

    Maggio, Gaspare; Fragola, Joseph R.

    1999-01-01

    The development of next generation systems often carries with it the promise of improved performance, greater reliability, and reduced operational costs. These expectations arise from the use of novel designs, new materials, advanced integration and production technologies intended for functionality replacing the previous generation. However, the novelty of these nascent technologies is accompanied by lack of operational experience and, in many cases, no actual testing as well. Therefore some of the enthusiasm surrounding most new technologies may be due to inflated aspirations from lack of knowledge rather than actual future expectations. This paper proposes a design heritage approach for improved reliability forecasting of advanced system components. The basis of the design heritage approach is to relate advanced system components to similar designs currently in operation. The demonstrated performance of these components could then be used to forecast the expected performance and reliability of comparable advanced technology components. In this approach the greater the divergence of the advanced component designs from the current systems the higher the uncertainty that accompanies the associated failure estimates. Designers of advanced systems are faced with many difficult decisions. One of the most common and more difficult types of these decisions are those related to the choice between design alternatives. In the past decision-makers have found these decisions to be extremely difficult to make because they often involve the trade-off between a known performing fielded design and a promising paper design. When it comes to expected reliability performance the paper design always looks better because it is on paper and it addresses all the know failure modes of the fielded design. On the other hand there is a long, and sometimes very difficult road, between the promise of a paper design and its fulfillment; with the possibility that sometimes the reliability

  6. Current State of Agile User-Centered Design: A Survey

    Science.gov (United States)

    Hussain, Zahid; Slany, Wolfgang; Holzinger, Andreas

    Agile software development methods are quite popular nowadays and are being adopted at an increasing rate in the industry every year. However, these methods are still lacking usability awareness in their development lifecycle, and the integration of usability/User-Centered Design (UCD) into agile methods is not adequately addressed. This paper presents the preliminary results of a recently conducted online survey regarding the current state of the integration of agile methods and usability/UCD. A world wide response of 92 practitioners was received. The results show that the majority of practitioners perceive that the integration of agile methods with usability/UCD has added value to their adopted processes and to their teams; has resulted in the improvement of usability and quality of the product developed; and has increased the satisfaction of the end-users of the product developed. The top most used HCI techniques are low-fidelity prototyping, conceptual designs, observational studies of users, usability expert evaluations, field studies, personas, rapid iterative testing, and laboratory usability testing.

  7. DSM shareholder incentives: Current designs and economic theory

    Energy Technology Data Exchange (ETDEWEB)

    Stoft, S.; Eto, J.; Kito, S.

    1995-01-01

    This report reviews recent DSM shareholder incentive designs and performance at 10 US utilities identifies opportunities for regulators to improve the design of DSM shareholder incentive mechanisms to increase the procurement of cost-effective DSM resources. We develop six recommendations: (1) apply shared-savings incentives to DSM resource programs; (2) use markup incentives for individual programs only when net benefits are difficult to measure, but are known to be positive; (3) set expected incentive payments based on covering a utility`s {open_quotes}hidden costs,{close_quotes} which include some transitional management and risk-adjusted opportunity costs; (4) use higher marginal incentives rates than are currently found in practice, but limit total incentive payments by adding a fixed charge; (5) mitigate risks to regulators and utilities by lowering marginal incentive rates at high and low performance levels; and (6) use an aggregate incentive mechanism for all DSM resource programs, with limited exceptions (e.g., information programs where markups are more appropriate).

  8. Assessing a Methodological Proposal for the Design, Creation and Evaluation of Learning Objects Oriented to Educators with Diverse Educational and Technological Competencies

    Directory of Open Access Journals (Sweden)

    Jorge J. Maldonado

    2016-04-01

    Full Text Available This paper describes a methodological proposal for the design, creation and evaluation of Learning Objects (LOs. This study arises from the compilation and analysis of several LO design methodologies currently used in Ibero-America. This proposal, which has been named DICREVOA, defines five different phases: analysis, design (instructional and multimedia, implementation (LO and metadata, evaluation (from the perspective of both the producer and the consumer of the LO, and publishing. The methodology focuses not only on the teaching inexperienced, but also on those having a basic understanding of the technological and educational aspects related to LO design; therefore, the study emphasizes LO design activities centered around the Kolb cycle and the use of the ExeLearning tool in order to implement the LO core. Additionally, DICREVOA was used in a case study, which demonstrates how it provides a feasible mechanism for LO design and implementation withindifferent contexts. Finally, DICREVOA, the case study to which it was applied, and the results obtained are presented.

  9. DESIGN METHODOLOGY OF NETWORKED SOFTWARE EVOLUTION GROWTH BASED ON SOFTWARE PATTERNS

    Institute of Scientific and Technical Information of China (English)

    Keqing HE; Rong PENG; Jing LIU; Fei HE; Peng LIANG; Bing LI

    2006-01-01

    Recently, some new characteristics of complex networks attract the attentions of scientists in different fields, and lead to many kinds of emerging research directions. So far, most of the research work has been limited in discovery of complex network characteristics by structure analysis in large-scale software systems. This paper presents the theoretical basis, design method, algorithms and experiment results of the research. It firstly emphasizes the significance of design method of evolution growth for network topology of Object Oriented (OO) software systems, and argues that the selection and modulation of network models with various topology characteristics will bring un-ignorable effect on the process of design and implementation of OO software systems. Then we analyze the similar discipline of "negation of negation and compromise" between the evolution of network models with different topology characteristics and the development of software modelling methods. According to the analysis of the growth features of software patterns, we propose an object-oriented software network evolution growth method and its algorithms in succession. In addition, we also propose the parameter systems for Oosoftware system metrics based on complex network theory. Based on these parameter systems, it can analyze the features of various nodes, links and local-world, modulate the network topology and guide the software metrics. All these can be helpful to the detailed design, implementation and performance analysis. Finally, we focus on the application of the evolution algorithms and demonstrate it by a case study.Comparing the results from our early experiments with methodologies in empirical software engineering, we believe that the proposed software engineering design method is a computational software engineering approach based on complex network theory. We argue that this method should be greatly beneficial for the design, implementation, modulation and metrics of

  10. A probabilistic methodology for radar cross section prediction in conceptual aircraft design

    Science.gov (United States)

    Hines, Nathan Robert

    System effectiveness has increasingly become the prime metric for the evaluation of military aircraft. As such, it is the decision maker's/designer's goal to maximize system effectiveness. Industry and government research documents indicate that all future military aircraft will incorporate signature reduction as an attempt to improve system effectiveness and reduce the cost of attrition. Today's operating environments demand low observable aircraft which are able to reliably take out valuable, time critical targets. Thus it is desirable to be able to design vehicles that are balanced for increased effectiveness. Previous studies have shown that shaping of the vehicle is one of the most important contributors to radar cross section, a measure of radar signature, and must be considered from the very beginning of the design process. Radar cross section estimation should be incorporated into conceptual design to develop more capable systems. This research strives to meet these needs by developing a conceptual design tool that predicts radar cross section for parametric geometries. This tool predicts the absolute radar cross section of the vehicle as well as the impact of geometry changes, allowing for the simultaneous tradeoff of the aerodynamic, performance, and cost characteristics of the vehicle with the radar cross section. Furthermore, this tool can be linked to a campaign theater analysis code to demonstrate the changes in system and system of system effectiveness due to changes in aircraft geometry. A general methodology was developed and implemented and sample computer codes applied to prototype the proposed process. Studies utilizing this radar cross section tool were subsequently performed to demonstrate the capabilities of this method and show the impact that various inputs have on the outputs of these models. The F/A-18 aircraft configuration was chosen as a case study vehicle to perform a design space exercise and to investigate the relative impact of

  11. Human factors analysis and design methods for nuclear waste retrieval systems: Human factors design methodology and integration plan

    Science.gov (United States)

    Casey, S. M.

    1980-06-01

    The nuclear waste retrieval system intended to be used for the removal of storage canisters (each canister containing a spent fuel rod assembly) located in an underground salt bed depository is discussed. The implementation of human factors engineering principles during the design and construction of the retrieval system facilities and equipment is reported. The methodology is structured around a basic system development effort involving preliminary development, equipment development, personnel subsystem development, and operational test and evaluation. Examples of application of the techniques in the analysis of human tasks, and equipment required in the removal of spent fuel canisters is provided. The framework for integrating human engineering with the rest of the system development effort is documented.

  12. Methodology for the nuclear design validation of an Alternate Emergency Management Centre (CAGE

    Directory of Open Access Journals (Sweden)

    Hueso César

    2017-01-01

    Full Text Available The methodology is devised by coupling different codes. The study of weather conditions as part of the data of the site will determine the relative concentrations of radionuclides in the air using ARCON96. The activity in the air is characterized depending on the source and release sequence specified in NUREG-1465 by RADTRAD code, which provides results of the inner cloud source term contribution. Known activities and energy spectra are inferred using ORIGEN-S, which are used as input for the models of the outer cloud, filters and containment generated with MCNP5. The sum of the different contributions must meet the conditions of habitability specified by the CSN (Spanish Nuclear Regulatory Body (TEDE <50 mSv and equivalent dose to the thyroid <500 mSv within 30 days following the accident doses so that the dose is optimized by varying parameters including CAGE location, flow filtering need for recirculation, thicknesses and compositions of the walls, etc. The results for the most penalizing area meet the established criteria, and therefore the CAGE building design based on the methodology presented is radiologically validated.

  13. The Design of Cognitive Social Simulation Framework using Statistical Methodology in the Domain of Academic Science

    Directory of Open Access Journals (Sweden)

    R. Sivakumar

    2013-05-01

    Full Text Available Modeling the behavior of the cognitive architecture in the context of social simulation using statistical methodologies is currently a growing research area. Normally, a cognitive architecture for an intelligent agent involves artificial computational process which exemplifies theories of cognition in computer algorithms under the consideration of state space. More specifically, for such cognitive system with large state space the problem like large tables and data sparsity are faced. Hence in this paper, we have proposed a method using a value iterative approach based on Q-learning algorithm, with function approximation technique to handle the cognitive systems with large state space. From the experimental results in the application domain of academic science it has been verified that the proposed approach has better performance compared to its existing approaches.

  14. A methodology for the efficient integration of transient constraints in the design of aircraft dynamic systems

    Science.gov (United States)

    Phan, Leon L.

    The motivation behind this thesis mainly stems from previous work performed at Hispano-Suiza (Safran Group) in the context of the European research project "Power Optimised Aircraft". Extensive testing on the COPPER Bird RTM, a test rig designed to characterize aircraft electrical networks, demonstrated the relevance of transient regimes in the design and development of dynamic systems. Transient regimes experienced by dynamic systems may have severe impacts on the operation of the aircraft. For example, the switching on of a high electrical load might cause a network voltage drop inducing a loss of power available to critical aircraft systems. These transient behaviors are thus often regulated by dynamic constraints, requiring the dynamic signals to remain within bounds whose values vary with time. The verification of these peculiar types of constraints, which generally requires high-fidelity time-domain simulation, intervenes late in the system development process, thus potentially causing costly design iterations. The research objective of this thesis is to develop a methodology that integrates the verification of dynamic constraints in the early specification of dynamic systems. In order to circumvent the inefficiencies of time-domain simulation, multivariate dynamic surrogate models of the original time-domain simulation models are generated, building on a nonlinear system identification technique using wavelet neural networks (or wavenets), which allow the multiscale nature of transient signals to be captured. However, training multivariate wavenets can become computationally prohibitive as the number of design variables increases. Therefore, an alternate approach is formulated, in which dynamic surrogate models using sigmoid-based neural networks are used to emulate the transient behavior of the envelopes of the time-domain response. Thus, in order to train the neural network, the envelopes are extracted by first separating the scales of the dynamic response

  15. A generic methodology for the design of sustainable carbon dioxide utilization processes using superstructure optimization

    DEFF Research Database (Denmark)

    Frauzem, Rebecca; Gani, Rafiqul

    ) is the primary greenhouse gas that is targeted via carbon capture and storage (CCS) as well as carbon capture and utilization (CCU) [1]. Carbon capture and utilization is showing promise because, in contrast with carbon capture and storage, it takes the captured carbon dioxide and makes further use of it......Global warming and other environmental concerns are fueling increased focus on sustainability resulting in new and stringent guidelines, especially with regard to emissions [1]. Greenhouse gases are prevalent and among harmful emissions that are targeted to be reduced; carbon dioxide (CO2......, including as an extractive agent or raw material. Chemical conversion, an important element of utilization, involves the use of carbon dioxide as a reactant in the production of chemical compounds [2]. However, for feasible implementation, a systematic methodology is needed for the design of the utilization...

  16. Transmutation of singularities and zeros in graded index optical instruments: a methodology for designing practical devices.

    Science.gov (United States)

    Hooper, I R; Philbin, T G

    2013-12-30

    We describe a design methodology for modifying the refractive index profile of graded-index optical instruments that incorporate singularities or zeros in their refractive index. The process maintains the device performance whilst resulting in graded profiles that are all-dielectric, do not require materials with unrealistic values, and that are impedance matched to the bounding medium. This is achieved by transmuting the singularities (or zeros) using the formalism of transformation optics, but with an additional boundary condition requiring the gradient of the co-ordinate transformation be continuous. This additional boundary condition ensures that the device is impedance matched to the bounding medium when the spatially varying permittivity and permeability profiles are scaled to realizable values. We demonstrate the method in some detail for an Eaton lens, before describing the profiles for an "invisible disc" and "multipole" lenses.

  17. Mixed culture optimization for marigold flower ensilage via experimental design and response surface methodology.

    Science.gov (United States)

    Navarrete-Bolaños, José Luis; Jiménez-Islas, Hugo; Botello-Alvarez, Enrique; Rico-Martínez, Ramiro

    2003-04-09

    Endogenous microorganisms isolated from the marigold flower (Tagetes erecta) were studied to understand the events taking place during its ensilage. Studies of the cellulase enzymatic activity and the ensilage process were undertaken. In both studies, the use of approximate second-order models and multiple lineal regression, within the context of an experimental mixture design using the response surface methodology as optimization strategy, determined that the microorganisms Flavobacterium IIb, Acinetobacter anitratus, and Rhizopus nigricans are the most significant in marigold flower ensilage and exhibit high cellulase activity. A mixed culture comprised of 9.8% Flavobacterium IIb, 41% A. anitratus, and 49.2% R. nigricans used during ensilage resulted in an increased yield of total xanthophylls extracted of 24.94 g/kg of dry weight compared with 12.92 for the uninoculated control ensilage.

  18. Transmutation of singularities and zeros in graded index optical instruments: a methodology for designing practical devices

    CERN Document Server

    Hooper, I R

    2014-01-01

    We describe a design methodology for modifying the refractive index profile of graded-index optical instruments that incorporate singularities or zeros in their refractive index. The process maintains the device performance whilst resulting in graded profiles that are all-dielectric, do not require materials with unrealistic values, and that are impedance matched to the bounding medium. This is achieved by transmuting the singularities (or zeros) using the formalism of transformation optics, but with an additional boundary condition requiring the gradient of the co- ordinate transformation be continuous. This additional boundary condition ensures that the device is impedance matched to the bounding medium when the spatially varying permittivity and permeability profiles are scaled to realizable values. We demonstrate the method in some detail for an Eaton lens, before describing the profiles for an "invisible disc" and "multipole" lenses.

  19. Methodologies for tracking learning paths: designing the online research study Making a Filmmaker

    Directory of Open Access Journals (Sweden)

    Lisbeth Frølunde

    2009-06-01

    Full Text Available The article concerns the design of a collaborative research project (2008-09 entitled Making a Filmmaker, which examines how young Scandinavian filmmakers create their own learning paths in formal and/or informal contexts. Our interest is in how learning experiences and contexts motivate the young filmmakers: what furthers their interest and/or hinders it, and what learning patterns emerge. The aim of this article is to present and discuss issues regarding the methodology and methods of the study, such as developing a relationship with interviewees when conducting interviews online (using MSN. We suggest two considerations about using online interviews: how the interviewees value the given subject of conversation and their familiarity with being online. The benefit of getting online communication with the young filmmakers is the ease it offers, because it is both practical and appropriates a meeting platform that is familiar to our participants.

  20. A literature review of applied adaptive design methodology within the field of oncology in randomised controlled trials and a proposed extension to the CONSORT guidelines.

    Science.gov (United States)

    Mistry, Pankaj; Dunn, Janet A; Marshall, Andrea

    2017-07-18

    The application of adaptive design methodology within a clinical trial setting is becoming increasingly popular. However the application of these methods within trials is not being reported as adaptive designs hence making it more difficult to capture the emerging use of these designs. Within this review, we aim to understand how adaptive design methodology is being reported, whether these methods are explicitly stated as an 'adaptive design' or if it has to be inferred and to identify whether these methods are applied prospectively or concurrently. Three databases; Embase, Ovid and PubMed were chosen to conduct the literature search. The inclusion criteria for the review were phase II, phase III and phase II/III randomised controlled trials within the field of Oncology that published trial results in 2015. A variety of search terms related to adaptive designs were used. A total of 734 results were identified, after screening 54 were eligible. Adaptive designs were more commonly applied in phase III confirmatory trials. The majority of the papers performed an interim analysis, which included some sort of stopping criteria. Additionally only two papers explicitly stated the term 'adaptive design' and therefore for most of the papers, it had to be inferred that adaptive methods was applied. Sixty-five applications of adaptive design methods were applied, from which the most common method was an adaptation using group sequential methods. This review indicated that the reporting of adaptive design methodology within clinical trials needs improving. The proposed extension to the current CONSORT 2010 guidelines could help capture adaptive design methods. Furthermore provide an essential aid to those involved with clinical trials.