WorldWideScience

Sample records for cumulative radiation effects

  1. Cumulative radiation effect

    International Nuclear Information System (INIS)

    Kirk, J.; Gray, W.M.; Watson, E.R.

    1977-01-01

    In five previous papers, the concept of Cumulative Radiation Effect (CRE) has been presented as a scale of accumulative sub-tolerance radiation damage, with a unique value of the CRE describing a specific level of radiation effect. Simple nomographic and tabular methods for the solution of practical problems in radiotherapy are now described. An essential feature of solving a CRE problem is firstly to present it in a concise and readily appreciated form, and, to do this, nomenclature has been introduced to describe schedules and regimes as compactly as possible. Simple algebraic equations have been derived to describe the CRE achieved by multi-schedule regimes. In these equations, the equivalence conditions existing at the junctions between schedules are not explicit and the equations are based on the CREs of the constituent schedules assessed individually without reference to their context in the regime as a whole. This independent evaluation of CREs for each schedule has resulted in a considerable simplification in the calculation of complex problems. The calculations are further simplified by the use of suitable tables and nomograms, so that the mathematics involved is reduced to simple arithmetical operations which require at the most the use of a slide rule but can be done by hand. The order of procedure in the presentation and calculation of CRE problems can be summarised in an evaluation procedure sheet. The resulting simple methods for solving practical problems of any complexity on the CRE-system are demonstrated by a number of examples. (author)

  2. Cumulative radiation effect

    International Nuclear Information System (INIS)

    Kirk, J.; Cain, O.; Gray, W.M.

    1977-01-01

    Cumulative Radiation Effect (CRE) represents a scale of accumulative sub-tolerance radiation damage, with a unique value of the CRE describing a specific level of radiation effect. Computer calculations have been used to simplify the evaluation of problems associated with the applications of the CRE-system in radiotherapy. In a general appraisal of the applications of computers to the CRE-system, the various problems encountered in clinical radiotherapy have been categorised into those involving the evaluation of a CRE at a point in tissue and those involving the calculation of CRE distributions. As a general guide, the computer techniques adopted at the Glasgow Institute of Radiotherapeutics for the solution of CRE problems are presented, and consist basically of a package of three interactive programs for point CRE calculations and a Fortran program which calculates CRE distributions for iso-effect treatment planning. Many examples are given to demonstrate the applications of these programs, and special emphasis has been laid on the problem of treating a point in tissue with different doses per fraction on alternate treatment days. The wide range of possible clinical applications of the CRE-system has been outlined and described under the categories of routine clinical applications, retrospective and prospective surveys of patient treatment, and experimental and theoretical research. Some of these applications such as the results of surveys and studies of time optimisation of treatment schedules could have far-reaching consequences and lead to significant improvements in treatment and cure rates with the minimum damage to normal tissue. (author)

  3. An investigation of the alternating fractionation formula of the Cumulative Radiation Effect

    International Nuclear Information System (INIS)

    Hamlet, R.; Kirk, J.; Perry, A.M.

    1980-01-01

    The alternating fractionation formula of the Cumulative Radiation Effect (CRE) system was investigated using the mouse intestinal crypt system as a method of assessment of the amount of radiation damage in a normal tissue. The experimental results revealed that the formula is correct in predicting an increased effect with alternating large and small sized fractions, when compared with a standard schedule where the fraction size was kept constant but achieved the same total dose. However, the results also demonstrated that the order in which the alternate fractions were administered affected the amount of radiation damage produced in the tissue. This observation is in contradiction to another prediction of the formula, that the order in which equal numbers of fractions of different magnitudes are administered, will have no effect on the biological end point. The formula, therefore, is only an approximate model of radiation damage in normal tissue and much more information is required before it can be improved upon. (author)

  4. Experimental assessment of cumulative temperature and UV-B radiation effects on Mediterranean plankton metabolism

    KAUST Repository

    Garcia-Corral, Lara S.

    2015-07-07

    The Mediterranean Sea is a vulnerable region for climate change, warming at higher rates compare to the global ocean. Warming leads to increased stratification of the water column and enhanced the oligotrophic nature of the Mediterranean Sea. The oligotrophic waters are already highly transparent, however, exposure of Mediterranean plankton to ultraviolet radiation (UV-B and UV-A) may increase further if the waters become more oligotrophic, thereby, allowing a deeper UV radiation penetration and likely enhancing impacts to biota. Here we experimentally elucidate the cumulative effects of warming and natural UV-B radiation on the net community production (NCP) of plankton communities. We conducted five experiments at monthly intervals, from June to October 2013, and evaluated the responses of NCP to ambient UV-B radiation and warming (+3°C), alone and in combination, in a coastal area of the northwest Mediterranean Sea. UV-B radiation and warming lead to reduced NCP and resulted in a heterotrophic (NCP < 0) metabolic balance. Both UV-B radiation and temperature, showed a significant individual effect in NCP across treatments and time. However, their joint effect showed to be synergistic as the interaction between them (UV × Temp) was statistically significant in most of the experiments performed. Our results showed that both drivers, would affect the gas exchange of CO2−O2 from and to the atmosphere and the role of plankton communities in the Mediterranean carbon cycle.

  5. Experimental assessment of cumulative temperature and UV-B radiation effects on Mediterranean plankton metabolism

    Directory of Open Access Journals (Sweden)

    Lara S. eGarcia-Corral

    2015-07-01

    Full Text Available The Mediterranean Sea is a vulnerable region for climate change, warming at higher rates compare to the global ocean. Warming leads to increased stratification of the water column and enhanced the oligotrophic nature of the Mediterranean Sea. The oligotrophic waters are already highly transparent, however, exposure of Mediterranean plankton to ultraviolet radiation (UV-B and UV-A may increase further if the waters become more oligotrophic, thereby, allowing a deeper UV radiation penetration and likely enhancing impacts to biota.Here we experimentally elucidate the cumulative effects of warming and natural UV-B radiation on the net community production (NCP of plankton communities. We conducted five experiments at monthly intervals, from June to October 2013, and evaluated the responses of NCP to ambient UV-B radiation and warming (+3ºC, alone and in combination, in a coastal area of the northwest Mediterranean Sea. UV-B radiation and warming lead to reduced net community production and resulted in a heterotrophic (NCP<0 metabolic balance. Both UV-B radiation and temperature, showed a significant individual effect in NCP across treatments and time. However, their joint effect showed to be synergistic as the interaction between them (UV x Temp was statistically significant in most of the experiments performed. Our results showed that both drivers, would affect the gas exchange of CO2-O2 from and to the atmosphere and the role of plankton communities in the Mediterranean carbon cycle

  6. Cumulative total effective whole-body radiation dose in critically ill patients.

    Science.gov (United States)

    Rohner, Deborah J; Bennett, Suzanne; Samaratunga, Chandrasiri; Jewell, Elizabeth S; Smith, Jeffrey P; Gaskill-Shipley, Mary; Lisco, Steven J

    2013-11-01

    Uncertainty exists about a safe dose limit to minimize radiation-induced cancer. Maximum occupational exposure is 20 mSv/y averaged over 5 years with no more than 50 mSv in any single year. Radiation exposure to the general population is less, but the average dose in the United States has doubled in the past 30 years, largely from medical radiation exposure. We hypothesized that patients in a mixed-use surgical ICU (SICU) approach or exceed this limit and that trauma patients were more likely to exceed 50 mSv because of frequent diagnostic imaging. Patients admitted into 15 predesignated SICU beds in a level I trauma center during a 30-day consecutive period were prospectively observed. Effective dose was determined using Huda's method for all radiography, CT imaging, and fluoroscopic examinations. Univariate and multivariable linear regressions were used to analyze the relationships between observed values and outcomes. Five of 74 patients (6.8%) exceeded exposures of 50 mSv. Univariate analysis showed trauma designation, length of stay, number of CT scans, fluoroscopy minutes, and number of general radiographs were all associated with increased doses, leading to exceeding occupational exposure limits. In a multivariable analysis, only the number of CT scans and fluoroscopy minutes remained significantly associated with increased whole-body radiation dose. Radiation levels frequently exceeded occupational exposure standards. CT imaging contributed the most exposure. Health-care providers must practice efficient stewardship of radiologic imaging in all critically ill and injured patients. Diagnostic benefit must always be weighed against the risk of cumulative radiation dose.

  7. Cumulative effects of Te precipitates in CdZnTe radiation detectors

    International Nuclear Information System (INIS)

    Bolotnikov, A.E.; Camarda, G.S.; Carini, G.A.; Cui, Y.; Li, L.; James, R.B.

    2007-01-01

    High-quality radiation detector-grade CdZnTe material is free from large-scale defects, such as grain boundaries, twins, and large Te or Cd inclusions (>50 μm), although it usually contains high concentrations of uniformly distributed Te inclusions and precipitates, typically of ∼20-μm-diameter size or smaller. We address the effects of the small-size Te precipitates on charge collection in CZT detectors, the significance of which is not yet well characterized. The strong correlation that we earlier found between the high-resolution X-ray maps and IR images proved that even small Te precipitates can trap substantial fractions of charge from the electron cloud. In this work, we modeled the transport of an electron cloud across idealized CZT devices containing Te precipitates to demonstrate that their cumulative effect can explain the degradation of energy resolution and the detection efficiency losses observed in actual CZT devices. Due to lack of experimental data on how the Te precipitates interact with an electron cloud, we developed a simplified (phenomenological) model based on the geometrical aspects of the problem. Despite its simplicity, the model correctly reproduced many experimental facts and gave quantitative predictions on the extent to which the presence of Te precipitates and inclusions can be tolerated. The broadening of the electron cloud due to repulsion and diffusion is at the core of the problem, making even low concentrations of small precipitates important in the device's performance

  8. Cumulative radiation dose of multiple trauma patients during their hospitalization

    International Nuclear Information System (INIS)

    Wang Zhikang; Sun Jianzhong; Zhao Zudan

    2012-01-01

    Objective: To study the cumulative radiation dose of multiple trauma patients during their hospitalization and to analyze the dose influence factors. Methods: The DLP for CT and DR were retrospectively collected from the patients during June, 2009 and April, 2011 at a university affiliated hospital. The cumulative radiation doses were calculated by summing typical effective doses of the anatomic regions scanned. Results: The cumulative radiation doses of 113 patients were collected. The maximum,minimum and the mean values of cumulative effective doses were 153.3, 16.48 mSv and (52.3 ± 26.6) mSv. Conclusions: Multiple trauma patients have high cumulative radiation exposure. Therefore, the management of cumulative radiation doses should be enhanced. To establish the individualized radiation exposure archives will be helpful for the clinicians and technicians to make decision whether to image again and how to select the imaging parameters. (authors)

  9. Cumulative environmental effects. Summary

    International Nuclear Information System (INIS)

    2012-01-01

    This report presents a compilation of knowledge about the state of the environment and human activity in the Norwegian part of the North Sea and Skagerrak. The report gives an overview of pressures and impacts on the environment from normal activity and in the event of accidents. This is used to assess the cumulative environmental effects, which factors have most impact and where the impacts are greatest, and to indicate which problems are expected to be most serious in the future. The report is intended to provide relevant information that can be used in the management of the marine area in the future. It also provides input for the identification of environmental targets and management measures for the North Sea and Skagerrak.(Author)

  10. Cumulative environmental effects. Summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    This report presents a compilation of knowledge about the state of the environment and human activity in the Norwegian part of the North Sea and Skagerrak. The report gives an overview of pressures and impacts on the environment from normal activity and in the event of accidents. This is used to assess the cumulative environmental effects, which factors have most impact and where the impacts are greatest, and to indicate which problems are expected to be most serious in the future. The report is intended to provide relevant information that can be used in the management of the marine area in the future. It also provides input for the identification of environmental targets and management measures for the North Sea and Skagerrak.(Author)

  11. Maintenance hemodialysis patients have high cumulative radiation exposure.

    LENUS (Irish Health Repository)

    Kinsella, Sinead M

    2010-10-01

    Hemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.

  12. Experimental assessment of cumulative temperature and UV-B radiation effects on Mediterranean plankton metabolism

    KAUST Repository

    Garcia-Corral, Lara S.; Martinez Ayala, Juan; Duarte, Carlos M.; Agusti, Susana

    2015-01-01

    . The oligotrophic waters are already highly transparent, however, exposure of Mediterranean plankton to ultraviolet radiation (UV-B and UV-A) may increase further if the waters become more oligotrophic, thereby, allowing a deeper UV radiation penetration and likely

  13. Cumulative radiation exposure in children with cystic fibrosis.

    LENUS (Irish Health Repository)

    O'Reilly, R

    2010-02-01

    This retrospective study calculated the cumulative radiation dose for children with cystic fibrosis (CF) attending a tertiary CF centre. Information on 77 children with a mean age of 9.5 years, a follow up time of 658 person years and 1757 studies including 1485 chest radiographs, 215 abdominal radiographs and 57 computed tomography (CT) scans, of which 51 were thoracic CT scans, were analysed. The average cumulative radiation dose was 6.2 (0.04-25) mSv per CF patient. Cumulative radiation dose increased with increasing age and number of CT scans and was greater in children who presented with meconium ileus. No correlation was identified between cumulative radiation dose and either lung function or patient microbiology cultures. Radiation carries a risk of malignancy and children are particularly susceptible. Every effort must be made to avoid unnecessary radiation exposure in these patients whose life expectancy is increasing.

  14. Cumulative effective radiation dose received by blunt trauma patients arriving to a military level I trauma center from point of injury and interhospital transfers.

    Science.gov (United States)

    Van Arnem, Kerri A; Supinski, David P; Tucker, Jonathan E; Varney, Shawn

    2016-12-01

    Trauma patients sustaining blunt injuries are exposed to multiple radiologic studies. Evidence indicates that the risk of cancer from exposure to ionizing radiation rises in direct proportion to the cumulative effective dose (CED) received. The purpose of this study is to quantify the amount of ionizing radiation accumulated when arriving directly from point of injury to San Antonio Military Medical Center (SAMMC), a level I trauma center, compared with those transferred from other facilities. A retrospective record review was conducted from 1st January 2010 through 31st December 2012. The SAMMC trauma registry, electronic medical records, and the digital radiology imaging system were searched for possible candidates. The medical records were then analyzed for sex, age, mechanism of injury, received directly from point of injury (direct group), transfer from another medical facility (transfer group), computed tomographic scans received, dose-length product, CED of radiation, and injury severity score. A diagnostic imaging physicist then calculated the estimated CED each subject received based on the dose-length product of each computed tomographic scan. A total of 300 patients were analyzed, with 150 patients in the direct group and 150 patients in the transfer group. Both groups were similar in age and sex. Patients in the transfer group received a significantly greater CED of radiation compared with the direct group (mean, 37.6 mSv vs 28 mSv; P=.001). The radiation received in the direct group correlates with a lifetime attributable risk (LAR) of 1 in 357 compared with the transfer group with an increase in LAR to 1 in 266. Patients transferred to our facility received a 34% increase in ionizing radiation compared with patients brought directly from the injury scene. This increased dose of ionizing radiation contributes to the LAR of cancer and needs to be considered before repeating imaging studies. III. Published by Elsevier Inc.

  15. Cumulative effect of X-ray radiation and inflammatory reaction on the circadian rhythm of tyrosine aminotransferase in the liver of mice

    International Nuclear Information System (INIS)

    Jungowska-Klin, B.

    1980-01-01

    The activity of tyrosine aminotransferase (TAT) in the liver of mice subjected simultaneously to ionizing radiation and to local inflammatory process showed in the first 24 hours of the experiment statistically significant changes resulting from summation of the harmful effects of both factors. In the second 24-hour period an evident tendency was observed for return of a normal circadian rhythm of the enzyme. This points to presence of an endogenous mechanism of suppression of the manifestations of significant desynchronization of the circadian rhythm. The paper contains also a trial of mathematical analysis of changes in TAT activity in the circadian rhythm, a description and analysis or the suppression process, qualitative and quantitative determination of the phenomenon of cumulation of the effects of powerful stress factors acting on the animal organism. The obtained results were compared with the results of investigations of TAT activity changes obtained in the case of separate application of the stress factors selected for this experiment. (author)

  16. Cumulative effects assessment: Does scale matter?

    International Nuclear Information System (INIS)

    Therivel, Riki; Ross, Bill

    2007-01-01

    Cumulative effects assessment (CEA) is (or should be) an integral part of environmental assessment at both the project and the more strategic level. CEA helps to link the different scales of environmental assessment in that it focuses on how a given receptor is affected by the totality of plans, projects and activities, rather than on the effects of a particular plan or project. This article reviews how CEAs consider, and could consider, scale issues: spatial extent, level of detail, and temporal issues. It is based on an analysis of Canadian project-level CEAs and UK strategic-level CEAs. Based on a review of literature and, especially, case studies with which the authors are familiar, it concludes that scale issues are poorly considered at both levels, with particular problems being unclear or non-existing cumulative effects scoping methodologies; poor consideration of past or likely future human activities beyond the plan or project in question; attempts to apportion 'blame' for cumulative effects; and, at the plan level, limited management of cumulative effects caused particularly by the absence of consent regimes. Scale issues are important in most of these problems. However both strategic-level and project-level CEA have much potential for managing cumulative effects through better siting and phasing of development, demand reduction and other behavioural changes, and particularly through setting development consent rules for projects. The lack of strategic resource-based thresholds constrains the robust management of strategic-level cumulative effects

  17. Cumulative effects of wind turbines. A guide to assessing the cumulative effects of wind energy development

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This guidance provides advice on how to assess the cumulative effects of wind energy developments in an area and is aimed at developers, planners, and stakeholders interested in the development of wind energy in the UK. The principles of cumulative assessment, wind energy development in the UK, cumulative assessment of wind energy development, and best practice conclusions are discussed. The identification and assessment of the cumulative effects is examined in terms of global environmental sustainability, local environmental quality and socio-economic activity. Supplementary guidance for assessing the principle cumulative effects on the landscape, on birds, and on the visual effect is provided. The consensus building approach behind the preparation of this guidance is outlined in the annexes of the report.

  18. Cumulative watershed effects: a research perspective

    Science.gov (United States)

    Leslie M. Reid; Robert R. Ziemer

    1989-01-01

    A cumulative watershed effect (CWE) is any response to multiple land-use activities that is caused by, or results in, altered watershed function. The CWE issue is politically defined, as is the significance of particular impacts. But the processes generating CWEs are the traditional focus of geomorphology and ecology, and have thus been studied for decades. The CWE...

  19. Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades.

    LENUS (Irish Health Repository)

    O'Connell, Oisin J

    2012-06-01

    With the increasing life expectancy for patients with cystic fibrosis (CF), and a known predisposition to certain cancers, cumulative radiation exposure from radiologic imaging is of increasing significance. This study explores the estimated cumulative effective radiation dose over a 17-year period from radiologic procedures and changing trends of imaging modalities over this period.

  20. Cumulative Effect of Depression on Dementia Risk

    OpenAIRE

    Olazarán, J.; Trincado, R.; Bermejo-Pareja, F.

    2013-01-01

    Objective. To analyze a potential cumulative effect of life-time depression on dementia and Alzheimer's disease (AD), with control of vascular factors (VFs). Methods. This study was a subanalysis of the Neurological Disorders in Central Spain (NEDICES) study. Past and present depression, VFs, dementia status, and dementia due to AD were documented at study inception. Dementia status was also documented after three years. Four groups were created according to baseline data: never depression (n...

  1. Chapter 19. Cumulative watershed effects and watershed analysis

    Science.gov (United States)

    Leslie M. Reid

    1998-01-01

    Cumulative watershed effects are environmental changes that are affected by more than.one land-use activity and that are influenced by.processes involving the generation or transport.of water. Almost all environmental changes are.cumulative effects, and almost all land-use.activities contribute to cumulative effects

  2. Improving cumulative effects assessment in Alberta: Regional strategic assessment

    International Nuclear Information System (INIS)

    Johnson, Dallas; Lalonde, Kim; McEachern, Menzie; Kenney, John; Mendoza, Gustavo; Buffin, Andrew; Rich, Kate

    2011-01-01

    The Government of Alberta, Canada is developing a regulatory framework to better manage cumulative environmental effects from development in the province. A key component of this effort is regional planning, which will lay the primary foundation for cumulative effects management into the future. Alberta Environment has considered the information needs of regional planning and has concluded that Regional Strategic Assessment may offer significant advantages if integrated into the planning process, including the overall improvement of cumulative environmental effects assessment in the province.

  3. Cumulative Effect of Depression on Dementia Risk

    Directory of Open Access Journals (Sweden)

    J. Olazarán

    2013-01-01

    Full Text Available Objective. To analyze a potential cumulative effect of life-time depression on dementia and Alzheimer’s disease (AD, with control of vascular factors (VFs. Methods. This study was a subanalysis of the Neurological Disorders in Central Spain (NEDICES study. Past and present depression, VFs, dementia status, and dementia due to AD were documented at study inception. Dementia status was also documented after three years. Four groups were created according to baseline data: never depression (nD, past depression (pD, present depression (prD, and present and past depression (prpD. Logistic regression was used. Results. Data of 1,807 subjects were investigated at baseline (mean age 74.3, 59.3% women, and 1,376 (81.6% subjects were evaluated after three years. The prevalence of dementia at baseline was 6.7%, and dementia incidence was 6.3%. An effect of depression was observed on dementia prevalence (OR [CI 95%] 1.84 [1.01–3.35] for prD and 2.73 [1.08–6.87] for prpD, and on dementia due to AD (OR 1.98 [0.98–3.99] for prD and OR 3.98 [1.48–10.71] for prpD (fully adjusted models, nD as reference. Depression did not influence dementia incidence. Conclusions. Present depression and, particularly, present and past depression are associated with dementia at old age. Multiple mechanisms, including toxic effect of depression on hippocampal neurons, plausibly explain these associations.

  4. Cumulative ionizing radiation exposure in patients with end stage kidney disease: a 6-year retrospective analysis.

    LENUS (Irish Health Repository)

    Coyle, Joe

    2011-08-13

    OBJECTIVE: To quantify cumulative exposure to ionizing radiation in patients with end stage kidney disease (ESKD). To investigate factors which may be independently associated with risk of high cumulative effective dose (CED). MATERIALS AND METHODS: The study had local institutional review board ethical approval. We conducted a retrospective study of 394 period prevalent ESKD patients attending a single tertiary referral centre between 2004 and 2009. Patient demographics were obtained from case records. Details of radiological investigations were obtained from the institutional radiology computerized database. CED was calculated using standard procedure specific radiation levels. High exposure was defined as CED > 50 mSv, an exposure which has been reported to increase cancer mortality by 5%. Data were compared using Pearson χ(2) and Mann-Whitney U test or Kruskal-Wallis tests. RESULTS: 394 patients were followed for a median of 4 years (1518 patient years follow-up). Of these 63% were male. Seventeen percent of patients had a CED of >50 mSv. Computed tomography (CT) accounted for 9% of total radiological studies\\/procedures while contributing 61.4% of total study dose. Median cumulative dose and median dose per patient year were significantly higher in the hemodialysis (HD) group (15.13 and 5.79 mSv, respectively) compared to the post-transplant group (2.9 and 0.52 mSv, respectively) (P < 0.001). CONCLUSION: ESKD patients are at risk of cumulative exposure to significant levels of diagnostic radiation. The majority of this exposure is imparted as a result of CT examinations to patients in the HD group.

  5. Cumulative effects of forest management activities: how might they occur?

    Science.gov (United States)

    R. M. Rice; R. B. Thomas

    1985-01-01

    Concerns are often voiced about possible environmental damage as the result of the cumulative sedimentation effects of logging and forest road construction. In response to these concerns, National Forests are developing procedures to reduce the possibility that their activities may lead to unacceptable cumulative effects

  6. Cumulative effect in multiple production processes on nuclei

    International Nuclear Information System (INIS)

    Golubyatnikova, E.S.; Shmonin, V.L.; Kalinkin, B.N.

    1989-01-01

    It is shown that the cumulative effect is a natural result of the process of hadron multiple production in nuclear reactions. Interpretation is made of the universality of slopes of inclusive spectra and other characteristics of cumulative hadrons. The character of information from such reactions is discussed, which could be helpful in studying the mechanism of multiparticle production. 27 refs.; 4 figs

  7. Cumulative ionizing radiation during coronary diagnostic and interventional procedures

    International Nuclear Information System (INIS)

    Oyarzun C, Carlos; Ramirez, Alfredo

    2001-01-01

    The diagnostic ability of ionizing radiation is well known and has led to the development of high speed, high resolution axial tomography, for which we must assume that the patient population is being exposed to ionizing radiation that could become great. In cardiology, especially, we attend patients that have to undergo two or three angio graph, diagnostic and other therapeutic procedures, accumulating radiation doses that are ignored and are not recorded. The skin doses are shown that were received by 18 patients in procedures that included coronary angiography and that were measured with cesium thermoluminescent detectors, varying from 54 to 877 mSv. per procedure. We propose that a personal register be set up in Chile to record the magnitude of the radiation received by a patient (CO)

  8. Estimated cumulative radiation dose received by diagnostic imaging during staging and treatment of operable Ewing sarcoma 2005-2012

    Energy Technology Data Exchange (ETDEWEB)

    Johnsen, Boel [Haukeland University Hospital, Centre for Nuclear Medicine and PET, Department of Radiology, P.O. Box 1400, Bergen (Norway); Fasmer, Kristine Eldevik [Haukeland University Hospital, Department of Oncology, Medical Physics Section, Bergen (Norway); Boye, Kjetil [Norwegian Radium Hospital, Oslo University Hospital, Department of Oncology, Oslo (Norway); Rosendahl, Karen; Aukland, Stein Magnus [Haukeland University Hospital, Department of Radiology, Paediatric Section, Bergen (Norway); University of Bergen, Department of Clinical Medicine, Bergen (Norway); Trovik, Clement [University of Bergen, Department of Clinical Medicine, Bergen (Norway); Haukeland University Hospital, Department of Surgery, Orthopaedic Section, Bergen (Norway); Biermann, Martin [Haukeland University Hospital, Centre for Nuclear Medicine and PET, Department of Radiology, P.O. Box 1400, Bergen (Norway); University of Bergen, Department of Clinical Medicine, Bergen (Norway)

    2017-01-15

    Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether {sup 18}F-fluorodeoxyglucose positron emission tomography - computed tomography ({sup 18}F-FDG PET-CT) is a major contributor of radiation. Twenty Ewing sarcoma patients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT. (orig.)

  9. Estimated cumulative radiation dose received by diagnostic imaging during staging and treatment of operable Ewing sarcoma 2005-2012

    International Nuclear Information System (INIS)

    Johnsen, Boel; Fasmer, Kristine Eldevik; Boye, Kjetil; Rosendahl, Karen; Aukland, Stein Magnus; Trovik, Clement; Biermann, Martin

    2017-01-01

    Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether 18 F-fluorodeoxyglucose positron emission tomography - computed tomography ( 18 F-FDG PET-CT) is a major contributor of radiation. Twenty Ewing sarcoma patients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT. (orig.)

  10. [Analysis of the cumulative solar ultraviolet radiation in Mexico].

    Science.gov (United States)

    Castanedo-Cázares, Juan Pablo; Torres-Álvarez, Bertha; Portales-González, Bárbara; Martínez-Rosales, Karla; Hernández-Blanco, Diana

    2016-01-01

    The incidence of skin cancer has increased in Mexico in recent years. Ultraviolet radiation is the main risk factor associated. Due to the need to develop strategies to prevent skin cancer, the aim of the study was to estimate the UV intensity in several representative regions of Mexico, the average annual UV dose of these populations, and the potential benefit of applying sunscreen at different ages. The intensity of UV radiation was quantified by remote and terrestrial radiometry. The dose of UV exposure was measured in minimal erythema doses using validated models for face and arms. The benefit of using a sunscreen was calculated with the use of a sunscreen with SPF 15 from birth to age 70. The UV radiation is lower in December and greater in the period from May to July. The region with a lower annual dose is Tijuana; and the higher annual dose is in the Mexico City area. The annual difference between these regions was 58 %. Through life, a low SPF sunscreen can reduce up to 66 % of the received UV dose. The geographical location is a risk factor for accumulation of UV radiation in Mexico. Since childhood, people receive high amounts of it; however, most of this dose can be reduced using any commercially available sunscreen, if applied strategically.

  11. Cumulative radiation dose caused by radiologic studies in critically ill trauma patients.

    Science.gov (United States)

    Kim, Patrick K; Gracias, Vicente H; Maidment, Andrew D A; O'Shea, Michael; Reilly, Patrick M; Schwab, C William

    2004-09-01

    Critically ill trauma patients undergo many radiologic studies, but the cumulative radiation dose is unknown. The purpose of this study was to estimate the cumulative effective dose (CED) of radiation resulting from radiologic studies in critically ill trauma patients. The study group was composed of trauma patients at an urban Level I trauma center with surgical intensive care unit length of stay (LOS) greater than 30 days. The radiology records were reviewed. A typical effective dose per study for each type of plain film radiograph, computed tomographic scan, fluoroscopic study, and nuclear medicine study was used to calculate CED. Forty-six patients met criteria. The mean surgical intensive care unit and hospital LOS were 42.7 +/- 14.0 and 59.5 +/- 28.5 days, respectively. The mean Injury Severity Score was 32.2 +/- 15.0. The mean number of studies per patient was 70.1 +/- 29.0 plain film radiographs, 7.8 +/- 4.1 computed tomographic scans, 2.5 +/- 2.6 fluoroscopic studies, and 0.065 +/- 0.33 nuclear medicine study. The mean CED was 106 +/- 59 mSv per patient (range, 11-289 mSv; median, 104 mSv). Among age, mechanism, Injury Severity Score, and LOS, there was no statistically significant predictor of high CED. The mean CED in the study group was 30 times higher than the average yearly radiation dose from all sources for individuals in the United States. The theoretical additional morbidity attributable to radiologic studies was 0.78%. From a radiobiologic perspective, risk-to-benefit ratios of radiologic studies are favorable, given the importance of medical information obtained. Current practice patterns regarding use of radiologic studies appear to be acceptable.

  12. Cumulative effects of wind turbines. Volume 3: Report on results of consultations on cumulative effects of wind turbines on birds

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report gives details of the consultations held in developing the consensus approach taken in assessing the cumulative effects of wind turbines. Contributions on bird issues, and views of stakeholders, the Countryside Council for Wales, electric utilities, Scottish Natural Heritage, and the National Wind Power Association are reported. The scoping of key species groups, where cumulative effects might be expected, consideration of other developments, the significance of any adverse effects, mitigation, regional capacity assessments, and predictive models are discussed. Topics considered at two stakeholder workshops are outlined in the appendices.

  13. The challenges and opportunities in cumulative effects assessment

    Energy Technology Data Exchange (ETDEWEB)

    Foley, Melissa M., E-mail: mfoley@usgs.gov [U.S. Geological Survey, Pacific Coastal and Marine Science Center, 400 Natural Bridges, Dr., Santa Cruz, CA 95060 (United States); Center for Ocean Solutions, Stanford University, 99 Pacific St., Monterey, CA 93940 (United States); Mease, Lindley A., E-mail: lamease@stanford.edu [Center for Ocean Solutions, Stanford University, 473 Via Ortega, Stanford, CA 94305 (United States); Martone, Rebecca G., E-mail: rmartone@stanford.edu [Center for Ocean Solutions, Stanford University, 99 Pacific St., Monterey, CA 93940 (United States); Prahler, Erin E. [Center for Ocean Solutions, Stanford University, 473 Via Ortega, Stanford, CA 94305 (United States); Morrison, Tiffany H., E-mail: tiffany.morrison@jcu.edu.au [ARC Centre of Excellence for Coral Reef Studies, James Cook University, Townsville, QLD, 4811 (Australia); Murray, Cathryn Clarke, E-mail: cmurray@pices.int [WWF-Canada, 409 Granville Street, Suite 1588, Vancouver, BC V6C 1T2 (Canada); Wojcik, Deborah, E-mail: deb.wojcik@duke.edu [Nicholas School for the Environment, Duke University, 9 Circuit Dr., Durham, NC 27708 (United States)

    2017-01-15

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  14. The challenges and opportunities in cumulative effects assessment

    International Nuclear Information System (INIS)

    Foley, Melissa M.; Mease, Lindley A.; Martone, Rebecca G.; Prahler, Erin E.; Morrison, Tiffany H.; Murray, Cathryn Clarke; Wojcik, Deborah

    2017-01-01

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  15. The challenges and opportunities in cumulative effects assessment

    Science.gov (United States)

    Foley, Melissa M.; Mease, Lindley A; Martone, Rebecca G; Prahler, Erin E; Morrison, Tiffany H; Clarke Murray, Cathryn; Wojcik, Deborah

    2016-01-01

    The cumulative effects of increasing human use of the ocean and coastal zone have contributed to a rapid decline in ocean and coastal resources. As a result, scientists are investigating how multiple, overlapping stressors accumulate in the environment and impact ecosystems. These investigations are the foundation for the development of new tools that account for and predict cumulative effects in order to more adequately prevent or mitigate negative effects. Despite scientific advances, legal requirements, and management guidance, those who conduct assessments—including resource managers, agency staff, and consultants—continue to struggle to thoroughly evaluate cumulative effects, particularly as part of the environmental assessment process. Even though 45 years have passed since the United States National Environmental Policy Act was enacted, which set a precedent for environmental assessment around the world, defining impacts, baseline, scale, and significance are still major challenges associated with assessing cumulative effects. In addition, we know little about how practitioners tackle these challenges or how assessment aligns with current scientific recommendations. To shed more light on these challenges and gaps, we undertook a comparative study on how cumulative effects assessment (CEA) is conducted by practitioners operating under some of the most well-developed environmental laws around the globe: California, USA; British Columbia, Canada; Queensland, Australia; and New Zealand. We found that practitioners used a broad and varied definition of impact for CEA, which led to differences in how baseline, scale, and significance were determined. We also found that practice and science are not closely aligned and, as such, we highlight opportunities for managers, policy makers, practitioners, and scientists to improve environmental assessment.

  16. The effects of cumulative practice on mathematics problem solving.

    Science.gov (United States)

    Mayfield, Kristin H; Chase, Philip N

    2002-01-01

    This study compared three different methods of teaching five basic algebra rules to college students. All methods used the same procedures to teach the rules and included four 50-question review sessions interspersed among the training of the individual rules. The differences among methods involved the kinds of practice provided during the four review sessions. Participants who received cumulative practice answered 50 questions covering a mix of the rules learned prior to each review session. Participants who received a simple review answered 50 questions on one previously trained rule. Participants who received extra practice answered 50 extra questions on the rule they had just learned. Tests administered after each review included new questions for applying each rule (application items) and problems that required novel combinations of the rules (problem-solving items). On the final test, the cumulative group outscored the other groups on application and problem-solving items. In addition, the cumulative group solved the problem-solving items significantly faster than the other groups. These results suggest that cumulative practice of component skills is an effective method of training problem solving.

  17. Applicability of the tissue stem cell turnover concept on the validity of cumulative dose based radiation risk evaluation

    International Nuclear Information System (INIS)

    Otsuka, Kensuke; Hamada, Nobuyuki; Iwasaki, Toshiyasu; Yoshida, Kazuo

    2011-01-01

    The radiation protection system adopts the linear no-threshold model to achieve proper radiation protection for considering cancer risks resulting from radiation exposure. This model uses cumulative dose to a tissue for risk evaluation in which cumulative dose is related to the amount of DNA damage and consequential induction of gene mutation. In this concept, gene mutation accumulates in tissue stem cells, the putative target of carcinogenesis, with total dose given to the tissue. Unlike high-dose-rate exposure, epidemiological studies in high radiation background areas, such as Kerala in India, revealed that cancer risks is not elevated by the dose to the inhabitants, suggesting that there exists some mechanisms to eliminate the damage/mutation in the exposed tissue under extremely low-dose-rate exposure situations. In this report, the dynamics of tissue stem cell turnover is evaluated as a possible mechanism under extremely low-dose-rate exposure situations. To this end, we reviewed recent literatures studying tissue stem cell turnover, and found that great advances in stem cell research have made it possible to trace a fate of stem cells in tissues. Furthermore, turnover of tissue stem cells is found to occur after irradiation, due to competition of stem cells within tissues. This raises a possibility that radiation effects may not accumulate in a tissue depending on the dose-rate and duration of exposure period. (author)

  18. Experience of cumulative effects assessment in the UK

    Directory of Open Access Journals (Sweden)

    Piper Jake

    2004-01-01

    Full Text Available Cumulative effects assessment (CEA is a development of environmental impact assessment which attempts to take into account the wider picture of what impacts may affect the environment as a result of either multiple or linear projects, or development plans. CEA is seen as a further valuable tool in promoting sustainable development. The broader canvas upon which the assessment is made leads to a suite of issues such as complexity in methods and assessment of significance, the desirability of co-operation between developers and other parties, new ways of addressing mitigation and monitoring. After outlining the legislative position and the process of CEA, this paper looks at three cases studies in the UK where cumulative assessment has been carried out - the cases concern wind farms, major infrastructure and off-shore developments.

  19. Ecosystem assessment methods for cumulative effects at the regional scale

    International Nuclear Information System (INIS)

    Hunsaker, C.T.

    1989-01-01

    Environmental issues such as nonpoint-source pollution, acid rain, reduced biodiversity, land use change, and climate change have widespread ecological impacts and require an integrated assessment approach. Since 1978, the implementing regulations for the National Environmental Policy Act (NEPA) have required assessment of potential cumulative environmental impacts. Current environmental issues have encouraged ecologists to improve their understanding of ecosystem process and function at several spatial scales. However, management activities usually occur at the local scale, and there is little consideration of the potential impacts to the environmental quality of a region. This paper proposes that regional ecological risk assessment provides a useful approach for assisting scientists in accomplishing the task of assessing cumulative impacts. Critical issues such as spatial heterogeneity, boundary definition, and data aggregation are discussed. Examples from an assessment of acidic deposition effects on fish in Adirondack lakes illustrate the importance of integrated data bases, associated modeling efforts, and boundary definition at the regional scale

  20. Cumulative effective and individual organ dose levels in paediatric patients undergoing multiple catheterizations for congenital heart disease

    International Nuclear Information System (INIS)

    Jones, T.P.; Brennan, P.C.; Ryan, E.

    2017-01-01

    This study examines the cumulative radiation dose levels received by a group of children who underwent multiple cardiac catheterisation procedures during the investigation and management of congenital heart disease (CHD). The purpose is to calculate cumulative doses, identify higher dose individuals, outline the inconsistencies with risk assessment and encourage the establishment of dose databases in order to facilitate the longitudinal research necessary to better understand health risks. A retrospective review of patient records for 117 paediatric patients who have undergone two or more cardiac catheterizations for the investigation of CHD was undertaken. This cohort consisted of patients who were catheterised over a period from September 2002 to August 2014. The age distribution was from newborn to 17 y. Archived kerma-area product (P KA ) and fluoroscopy time (T) readings were retrieved and analysed. Cumulative effective and individual organ doses were determined. The cumulative P KA levels ranged from 1.8 to 651.2 Gycm 2 , whilst cumulative effective dose levels varied from 2 to 259 mSv. The cumulative fluoroscopy time was shown to vary from 8.1 to 193.5 min. Median cumulative organ doses ranged from 3 to 94 mGy. Cumulative effective dose levels are highly variable but may exceed 250 mSv. Individual organ and effective dose measurements remain useful for comparison purposes between institutions although current methodologies used for determining lifetime risks are inadequate. (authors)

  1. Problems of describing the cumulative effect in relativistic nuclear physics

    International Nuclear Information System (INIS)

    Baldin, A.M.

    1979-01-01

    The problem of describing the cumulative effect i.e., the particle production on nuclei in the range kinematically forbidden for one-nucleon collisions, is studied. Discrimination of events containing cumulative particles fixes configurations in the wave function of a nucleus, when several nucleons are closely spaced and their quark-parton components are collectivized. For the cumulative processes under consideration large distances between quarks are very important. The fundamental facts and theoretical interpretation of the quantum field theory and of the condensed media theory in the relativistic nuclear physics are presented in brief. The collisions of the relativistic nuclei with low momentum transfers is considered in a fast moving coordinate system. The basic parameter determining this type of collisions is the energy of nucleon binding in nuclei. It has been shown that the short-range correlation model provides a good presentation of many characteristics of the multiple particle production and it may be regarded as an approximate universal property of hadron interactions

  2. Cumulative Radiation Exposure during Follow-Up after Curative Surgery for Gastric Cancer

    International Nuclear Information System (INIS)

    Lee, Yeo Jin; Chung, Yong Eun; Lim, Joon Seok; Kim, Joo Hee; Kim, Young Jin; Lee, Hye Jeong; Kim, Myeong Jin; Kim, Ki Whang; You, Je Sung

    2012-01-01

    To quantify the cumulative effective dose (cED) of radiation due to repeated CT and PET/CT examinations after curative resection of gastric cancer and to assess the lifetime attributable risk (LAR) estimates based on Biological Effects of Ionizing Radiation VII models. Patients who underwent a curative resection for gastric cancer between January 2006 and December 2006 and were followed-up until May 2010 were included in this study. The cED was calculated by using the dose-length product values and conversion factors for quantitative risk assessment of radiation exposure. cED and LAR were compared between early and advanced gastric cancer patients and among American Joint Committee on Cancer TNM stage groups (stage I, II, and III). The nonparametric Mann-Whitney U and Kruskal-Wallis tests, followed by a post-hoc analysis with Bonferroni adjustment, were employed as part of the statistical analysis. The overall median cED was 57.8 mSv (interquartile range [IQR], 43.9-74.7). The cED was significantly higher in the advanced (median, 67.0; IQR, 49.1-102.3) than in the early gastric cancer group (median, 52.3; IQR, 41.5-67.9) (p < 0.001), and increased as the TNM stage increased. For radiation exposure, 62% of all patients received an estimated cED of over 50 mSv, while 11% of patients received over 100 mSv. The median LAR of cancer incidence was 0.28% (IQR, 0.20-0.40) and there were significant differences between the early gastric cancer and advanced gastric cancer group (p < 0.001) as well as among the three TNM stage groups (p = 0.015). The LAR of cancer incidence exceeded 1% in 2.4% of the patients. The cED increases proportionally along with tumor stage and, even in early gastric cancer or stage I patients, cED is much higher than that found among the general population. Considering the very good prognosis of early gastric cancer after curative surgery, the cED should be considered when designing a postoperative follow-up CT protocol.

  3. Prediction of a photovoltaic system performance using cumulative frequency curves of radiation

    Energy Technology Data Exchange (ETDEWEB)

    Lasnier, F; Sivoththaman, S [Asian Inst. of Technology, Bangkok (TH). Div. of Energy Technology

    1990-01-01

    The system performance of stand-alone photovoltaic systems is analysed. From the hourly radiation data for Bangkok (from 1984 to 1987) the cumulative frequency curves of radiation are generated and a typical meteorological day (TMD) is created each year. The system performance is determined using both the TMD radiation and the actual radiation values. The comparison results show that the TMD method can be applied for the sizing of stand-alone photovoltaic systems. The storage batteries of realistic sizes usually exhibit a daily cyclic variation in state-of-charge, with constant load consumption. Only very large and unrealistic sizes of batteries show a seasonal variation in state-of-charge. This is the fact that prompted the attempt to predict the system performance for a season by using a single representative day (TMD) of that season. Apart from giving reliable results, the TMD method significantly reduces the computation time and simplifies the process. (author).

  4. Cumulative Effects Assessment: Linking Social, Ecological, and Governance Dimensions

    Directory of Open Access Journals (Sweden)

    Marian Weber

    2012-06-01

    Full Text Available Setting social, economic, and ecological objectives is ultimately a process of social choice informed by science. In this special feature we provide a multidisciplinary framework for the use of cumulative effects assessment in land use planning. Forest ecosystems are facing considerable challenges driven by population growth and increasing demands for resources. In a suite of case studies that span the boreal forest of Western Canada to the interior Atlantic forest of Paraguay we show how transparent and defensible methods for scenario analysis can be applied in data-limited regions and how social dimensions of land use change can be incorporated in these methods, particularly in aboriginal communities that have lived in these ecosystems for generations. The case studies explore how scenario analysis can be used to evaluate various land use options and highlight specific challenges with identifying social and ecological responses, determining thresholds and targets for land use, and integrating local and traditional knowledge in land use planning. Given that land use planning is ultimately a value-laden and often politically charged process we also provide some perspective on various collective and expert-based processes for identifying cumulative impacts and thresholds. The need for good science to inform and be informed by culturally appropriate democratic processes calls for well-planned and multifaceted approaches both to achieve an informed understanding of both residents and governments of the interactive and additive changes caused by development, and to design action agendas to influence such change at the ecological and social level.

  5. The injury and cumulative effects on human skin by UV exposure from artificial fluorescence emission.

    Science.gov (United States)

    Tian, Yan; Liu, Wei; Niu, TianHui; Dai, CaiHong; Li, Xiaoxin; Cui, Caijuan; Zhao, Xinyan; E, Yaping; Lu, Hui

    2014-01-01

    The injury and cumulative effects of UV emission from fluorescence lamp were studied. UV intensity from fluorescence lamp was measured, and human skin samples (hips, 10 volunteers) were exposed to low-dose UV irradiation (three times per week for 13 consecutive weeks). Three groups were examined: control group without UV radiation; low-dose group with a cumulative dose of 50 J cm(-2) which was equivalent to irradiation of the face during indoor work for 1.5 years; and high-dose group with 1000 J cm(-2) cumulative dose equivalent to irradiation of the face during outdoor activities for 1 year. Specific indicators were measured before and after UVA irradiation. The findings showed that extending the low-dose UVA exposure decreased the skin moisture content and increased the transepidermal water loss as well as induced skin color changes (decreased L* value, increased M index). Furthermore, irradiated skin showed an increased thickness of cuticle and epidermis, skin edema, light color and unclear staining collagen fibers in the dermis, and elastic fiber fragmentation. In addition, MMP-1, p53 and SIRT1 expression was also increased. Long-term exposure of low-dose UVA radiation enhanced skin photoaging. The safety of the fluorescent lamp needs our attention. © 2014 The American Society of Photobiology.

  6. Cumulative effects in Swedish EIA practice - difficulties and obstacles

    International Nuclear Information System (INIS)

    Waernbaeck, Antoienette; Hilding-Rydevik, Tuija

    2009-01-01

    The importance of considering cumulative effects (CE) in the context of environmental assessment is manifested in the EU regulations. The demands on the contents of Environmental Impact Assessment (EIA) and Strategic Environmental Assessment (SEA) documents explicitly ask for CE to be described. In Swedish environmental assessment documents CE are rarely described or included. The aim of this paper is to look into the reasons behind this fact in the Swedish context. The paper describes and analyse how actors implementing the EIA and SEA legislation in Sweden perceive the current situation in relation to the legislative demands and the inclusion of cumulative effects. Through semi-structured interviews the following questions have been explored: Is the phenomenon of CE discussed and included in the EIA/SEA process? What do the actors include in and what is their knowledge of the term and concept of CE? Which difficulties and obstacles do these actors experience and what possibilities for inclusion of CE do they see in the EIA/SEA process? A large number of obstacles and hindrances emerged from the interviews conducted. It can be concluded from the analysis that the will to act does seem to exist. A lack of knowledge in respect of how to include cumulative effects and a lack of clear regulations concerning how this should be done seem to be perceived as the main obstacles. The knowledge of the term and the phenomenon is furthermore quite narrow and not all encompassing. They experience that there is a lack of procedures in place. They also seem to lack knowledge of methods in relation to how to actually work, in practice, with CE and how to include CE in the EIA/SEA process. It can be stated that the existence of this poor picture in relation to practice concerning CE in the context of impact assessment mirrors the existing and so far rather vague demands in respect of the inclusion and assessment of CE in Swedish EIA and SEA legislation, regulations, guidelines and

  7. In vitro propagation of Cypripedium guttatum using immature seed based on cumulative solar radiation after pollination

    International Nuclear Information System (INIS)

    Sasaki, Y.

    2000-01-01

    Cypripedium guttatum is one of the most endangered orchids in Japan. In vitro propagation is an important approach for conservation of the plant species. Generally, Cypripedium in vitro propagation is unstable, especially using immature seeds. Therefore, an in vitro propagation system that protocorm produces stable germination is required. In this study, one of the weather factors was tested to obtain stable immmature seeds for seedling production. From statistical analysis of the weather data, it was suggested that solar radiation affected the ripening of Cypripedium seed. From simulations of cumulative solar radiation, a seed 46 days after pollination is suitable for in vitro propagation in Akita. Using a seed 47 days after pollination of Cypripedium guttatum, seedlings were grown in hormone free 1/3 MS agar medium. In the case of adding 0.2 mg/L BAP, multiple shoots were observed. For root elongation of the seedling, hormone free medium was preferable to adding 0.2 mg/L NAA

  8. Estimated cumulative radiation dose from PET/CT in children with malignancies: a 5-year retrospective review

    International Nuclear Information System (INIS)

    Chawla, Soni C.; Federman, Noah; Zhang, Di; Nagata, Kristen; Nuthakki, Soujanya; McNitt-Gray, Michael; Boechat, M.I.

    2010-01-01

    The increasing use of serial PET/CT scans in the management of pediatric malignancies raises the important consideration of radiation exposure in children. To estimate the cumulative radiation dose from PET/CT studies to children with malignancy and to compare with the data in literature. Two hundred forty-eight clinical PET/CT studies performed on 78 patients (50 boys/28 girls, 1.3 to 18 years old from December 2002 to October 2007) were retrospectively reviewed under IRB approval. The whole-body effective dose (ED) estimates for each child were obtained by estimating the effective dose from each PET/CT exam performed using the ImPACT Patient Dosimetry Calculator for CT and OLINDA for PET. The average number of PET/CT studies was 3.2 per child (range: 1 to 14 studies). The average ED of an individual CT study was 20.3 mSv (range: 2.7 to 54.2), of PET study was 4.6 mSv (range: 0.4 to 7.7) and of PET/CT study was 24.8 mSv (range: 6.2 to 60.7). The average cumulative radiation dose per patient from CT studies was 64.4 mSv (range: 2.7 to 326), from PET studies was 14.5 mSv (range: 2.8 to 73) and from PET/CT studies was 78.9 mSv (range: 6.2 to 399). The radiation exposure from serial PET/CT studies performed in pediatric malignancies was considerable; however, lower doses can be used for both PET and CT studies. The ALARA principle must be applied without sacrificing diagnostic information. (orig.)

  9. TH-AB-207A-04: Assessment of Patients’ Cumulative Effective Dose From CT Examinations

    Energy Technology Data Exchange (ETDEWEB)

    Bostani, M; Cagnon, C; Sepahdari, A; Beckett, K; Oshiro, T; McNitt-Gray, M [UCLA School of Medicine, Los Angeles, CA (United States)

    2016-06-15

    Purpose: The Joint Commission requires institutions to consider patient’s age and recent imaging exams when deciding on the most appropriate type of imaging exam. Additionally, knowing patient’s imaging history can help prevent duplicate scans. Radiation dose management software affords new opportunities to identify and utilize patients with high cumulative doses as one proxy for subsequent review of imaging history and opportunities in avoiding redundant exams. Methods: Using dose management software (Radimetrics, Bayer Healthcare) a total of 72073 CT examinations performed from Jan 2015 to Jan 2016 were examined to categorize patients with a cumulative effective dose of 100 mSv and above. This threshold was selected based on epidemiological studies on populations exposed to radiation, which demonstrate a statistical increase of cancer risk at doses above 100 mSv. Histories of patients with highest cumulative dose and highest number of exams were further investigated by a Radiologist for appropriateness of recurrent studies and potential opportunities for reduction. Results: Out of 34762 patients, 927 (2.7%) were identified with a cumulative dose of 100 mSv and above. The highest cumulative dose (842 mSv) belonged to an oncology patient who underwent 2 diagnostic exams and 9 interventional ablative CT guided procedures. The patient with highest number of exams (56 counts) and cumulative dose of 170 mSv was a 17 year old trauma patient. An imaging history review of these two patients did not suggest any superfluous scans. Conclusion: Our limited pilot study suggests that recurrent CT exams for patients with oncologic or severe trauma history may be warranted and appropriate. As a result, for future studies we will be focusing on high dose patient cohorts not associated with oncology or severe trauma. Additionally, the review process itself has suggested areas for potential improvement in patient care, including improved documentation and Radiologist involvement

  10. TH-AB-207A-04: Assessment of Patients’ Cumulative Effective Dose From CT Examinations

    International Nuclear Information System (INIS)

    Bostani, M; Cagnon, C; Sepahdari, A; Beckett, K; Oshiro, T; McNitt-Gray, M

    2016-01-01

    Purpose: The Joint Commission requires institutions to consider patient’s age and recent imaging exams when deciding on the most appropriate type of imaging exam. Additionally, knowing patient’s imaging history can help prevent duplicate scans. Radiation dose management software affords new opportunities to identify and utilize patients with high cumulative doses as one proxy for subsequent review of imaging history and opportunities in avoiding redundant exams. Methods: Using dose management software (Radimetrics, Bayer Healthcare) a total of 72073 CT examinations performed from Jan 2015 to Jan 2016 were examined to categorize patients with a cumulative effective dose of 100 mSv and above. This threshold was selected based on epidemiological studies on populations exposed to radiation, which demonstrate a statistical increase of cancer risk at doses above 100 mSv. Histories of patients with highest cumulative dose and highest number of exams were further investigated by a Radiologist for appropriateness of recurrent studies and potential opportunities for reduction. Results: Out of 34762 patients, 927 (2.7%) were identified with a cumulative dose of 100 mSv and above. The highest cumulative dose (842 mSv) belonged to an oncology patient who underwent 2 diagnostic exams and 9 interventional ablative CT guided procedures. The patient with highest number of exams (56 counts) and cumulative dose of 170 mSv was a 17 year old trauma patient. An imaging history review of these two patients did not suggest any superfluous scans. Conclusion: Our limited pilot study suggests that recurrent CT exams for patients with oncologic or severe trauma history may be warranted and appropriate. As a result, for future studies we will be focusing on high dose patient cohorts not associated with oncology or severe trauma. Additionally, the review process itself has suggested areas for potential improvement in patient care, including improved documentation and Radiologist involvement

  11. Radiation effects

    International Nuclear Information System (INIS)

    Collings, E.W.

    1986-01-01

    An important cause of deterioration in superconducting magnets intended for high-energy physics and fusion-reactor applications is radiation damage. The present chapter deals chiefly with the effects of electron, proton, gamma and neutron irradiation on the properties of stabilized Ti-Nb-base composite superconductors. The authors examine the particle-accelerator environment, electron irradiation of Ti-Nb superconductor, proton irradiation of Ti-Nb superconductor and its stabilizer, and deuteron irradiation of Ti-Nb superconductor. A section discussing the fusion reactor environment in general is presented, and the two principal classes of fusion reactor based on the magnetic-confinement concept, namely the tokamak and the mirrormachine are examined. Also discussed is neutron irradiation of Cu/TiNb composite superconductors and critical current density of neutronirradiated Ti-Nb. Finally, radiation damage to stabilizer and insulating materials is described

  12. Health effects of ionizing radiation

    International Nuclear Information System (INIS)

    Radford, E.P.

    1980-01-01

    This presentation is restricted to the health effects of low doses of ionizing radiation. In general, these cumulative exposures are well below 100 rem, or about 50 times background or less. The two effects of interest in this dose range are genetic mutations and cancer production. The genetic effects will not be discussed in detail. The chief reason for the rise in risk estimates for cancer is the longer follow-up of exposed populations

  13. Cumulative Effects of Barriers on the Movements of Forest Birds

    Directory of Open Access Journals (Sweden)

    Marc Bélisle

    2002-01-01

    Full Text Available Although there is a consensus of opinion that habitat fragmentation has deleterious effects on animal populations, primarily by inhibiting dispersal among remaining patches, there have been few explicit demonstrations of the ways by which degraded habitats actually constrain individual movement. Two impediments are primarily responsible for this paucity: it is difficult to separate the effects of habitat fragmentation (configuration from habitat loss (composition, and conventional measures of fragmented habitats are assumed to be, but probably are not, isotropic. We addressed these limitations by standardizing differences in forest cover in a clearly anisotropic configuration of habitat fragmentation by conducting a homing experiment with three species of forest birds in the Bow Valley of Banff National Park, Canada. Birds were translocated (1.2-3.5  km either parallel or perpendicular to four/five parallel barriers that are assumed to impede the cross-valley travel of forest-dependent animals. Taken together, individuals exhibited longer return times when they were translocated across these barriers, but differences among species suggest a more complex interpretation. A long-distance migrant (Yellow-rumped Warbler, Dendroica coronata behaved as predicted, but a short-distance migrant (Golden-crowned Kinglet, Regulus satrapa was indifferent to barrier configuration. A resident (Red-breasted Nuthatch, Sitta canadensis exhibited longer return times when it was translocated parallel to the barriers. Our results suggest that an anisotropic arrangement of small, open areas in fragmented landscapes can have a cumulative barrier effect on the movement of forest animals, but that both modelers and managers will have to acknowledge potentially counterintuitive differences among species to predict the effect that these may have on individual movement and, ultimately, dispersal.

  14. Integrating environmental monitoring with cumulative effects management and decision making.

    Science.gov (United States)

    Cronmiller, Joshua G; Noble, Bram F

    2018-05-01

    Cumulative effects (CE) monitoring is foundational to emerging regional and watershed CE management frameworks, yet monitoring is often poorly integrated with CE management and decision-making processes. The challenges are largely institutional and organizational, more so than scientific or technical. Calls for improved integration of monitoring with CE management and decision making are not new, but there has been limited research on how best to integrate environmental monitoring programs to ensure credible CE science and to deliver results that respond to the more immediate questions and needs of regulatory decision makers. This paper examines options for the integration of environmental monitoring with CE frameworks. Based on semistructured interviews with practitioners, regulators, and other experts in the Lower Athabasca, Alberta, Canada, 3 approaches to monitoring system design are presented. First, a distributed monitoring system, reflecting the current approach in the Lower Athabasca, where monitoring is delegated to different external programs and organizations; second, a 1-window system in which monitoring is undertaken by a single, in-house agency for the purpose of informing management and regulatory decision making; third, an independent system driven primarily by CE science and understanding causal relationships, with knowledge adopted for decision support where relevant to specific management questions. The strengths and limitations of each approach are presented. A hybrid approach may be optimal-an independent, nongovernment, 1-window model for CE science, monitoring, and information delivery-capitalizing on the strengths of distributed, 1-window, and independent monitoring systems while mitigating their weaknesses. If governments are committed to solving CE problems, they must invest in the long-term science needed to do so; at the same time, if science-based monitoring programs are to be sustainable over the long term, they must be responsive to

  15. Cumulative effects of planned industrial development and climate change on marine ecosystems

    Directory of Open Access Journals (Sweden)

    Cathryn Clarke Murray

    2015-07-01

    Full Text Available With increasing human population, large scale climate changes, and the interaction of multiple stressors, understanding cumulative effects on marine ecosystems is increasingly important. Two major drivers of change in coastal and marine ecosystems are industrial developments with acute impacts on local ecosystems, and global climate change stressors with widespread impacts. We conducted a cumulative effects mapping analysis of the marine waters of British Columbia, Canada, under different scenarios: climate change and planned developments. At the coast-wide scale, climate change drove the largest change in cumulative effects with both widespread impacts and high vulnerability scores. Where the impacts of planned developments occur, planned industrial and pipeline activities had high cumulative effects, but the footprint of these effects was comparatively localized. Nearshore habitats were at greatest risk from planned industrial and pipeline activities; in particular, the impacts of planned pipelines on rocky intertidal habitats were predicted to cause the highest change in cumulative effects. This method of incorporating planned industrial development in cumulative effects mapping allows explicit comparison of different scenarios with the potential to be used in environmental impact assessments at various scales. Its use allows resource managers to consider cumulative effect hotspots when making decisions regarding industrial developments and avoid unacceptable cumulative effects. Management needs to consider both global and local stressors in managing marine ecosystems for the protection of biodiversity and the provisioning of ecosystem services.

  16. Cumulative effective dose associated with radiography and CT of adolescents with spinal injuries.

    Science.gov (United States)

    Lemburg, Stefan P; Peters, Soeren A; Roggenland, Daniela; Nicolas, Volkmar; Heyer, Christoph M

    2010-12-01

    The purpose of this study was to analyze the quantity and distribution of cumulative effective doses in diagnostic imaging of adolescents with spinal injuries. At a level 1 trauma center from July 2003 through June 2009, imaging procedures during initial evaluation and hospitalization and after discharge of all patients 10-20 years old with spinal fractures were retrospectively analyzed. The cumulative effective doses for all imaging studies were calculated, and the doses to patients with spinal injuries who had multiple traumatic injuries were compared with the doses to patients with spinal injuries but without multiple injuries. The significance level was set at 5%. Imaging studies of 72 patients (32 with multiple injuries; average age, 17.5 years) entailed a median cumulative effective dose of 18.89 mSv. Patients with multiple injuries had a significantly higher total cumulative effective dose (29.70 versus 10.86 mSv, p cumulative effective dose to multiple injury patients during the initial evaluation (18.39 versus 2.83 mSv, p cumulative effective dose. Adolescents with spinal injuries receive a cumulative effective dose equal to that of adult trauma patients and nearly three times that of pediatric trauma patients. Areas of focus in lowering cumulative effective dose should be appropriate initial estimation of trauma severity and careful selection of CT scan parameters.

  17. 14 CFR Section 18 - Objective Classification-Cumulative Effect of Changes in Accounting Principles

    Science.gov (United States)

    2010-01-01

    ... of Changes in Accounting Principles Section 18 Section 18 Aeronautics and Space OFFICE OF THE... Objective Classification—Cumulative Effect of Changes in Accounting Principles 98Cumulative Effect of Changes in Accounting Principles. Record here the difference between the amount of retained earnings at...

  18. Managing regional cumulative effects of oil sands development in Alberta, Canada

    International Nuclear Information System (INIS)

    Spaling, H.; Zwier, J.

    2000-01-01

    This paper demonstrates an approach to regional cumulative effects management using the case of oil sands development in Alberta, Canada. The 17 existing, approved, or planned projects, all concentrated in a relatively small region, pose significant challenges for conducting and reviewing cumulative effects assessment (CEA) on a project-by-project basis. In response, stakeholders have initiated a regional cumulative effects management system that is among the first such initiatives anywhere. Advantages of this system include (1) more efficient gathering and sharing of information, including a common regional database, (2) setting acceptable regional environmental thresholds for all projects, (3) collaborative assessment of similar cumulative effects from related projects, (4) co-ordinated regulatory review and approval process for overlapping CEAs, and (5) institutional empowerment from a Regional Sustainable Development Strategy administered by a public authority. This case provides a model for integrating project-based CEA with regional management of cumulative effects. (author)

  19. Summary report of a workshop on establishing cumulative effects thresholds : a suggested approach for establishing cumulative effects thresholds in a Yukon context

    International Nuclear Information System (INIS)

    2003-01-01

    Increasingly, thresholds are being used as a land and cumulative effects assessment and management tool. To assist in the management of wildlife species such as woodland caribou, the Department of Indian and Northern Affairs (DIAND) Environment Directorate, Yukon sponsored a workshop to develop and use cumulative thresholds in the Yukon. The approximately 30 participants reviewed recent initiatives in the Yukon and other jurisdictions. The workshop is expected to help formulate a strategic vision for implementing cumulative effects thresholds in the Yukon. The key to success resides in building relationships with Umbrella Final Agreement (UFA) Boards, the Development Assessment Process (DAP), and the Yukon Environmental and Socio-Economic Assessment Act (YESAA). Broad support is required within an integrated resource management framework. The workshop featured discussions on current science and theory of cumulative effects thresholds. Potential data and implementation issues were also discussed. It was concluded that thresholds are useful and scientifically defensible. The threshold research results obtained in Alberta, British Columbia and the Northwest Territories are applicable to the Yukon. One of the best tools for establishing and tracking thresholds is habitat effectiveness. Effects must be monitored and tracked. Biologists must share their information with decision makers. Interagency coordination and assistance should be facilitated through the establishment of working groups. Regional land use plans should include thresholds. 7 refs.

  20. Radiation dose effects, hardening of electronic components

    International Nuclear Information System (INIS)

    Dupont-Nivet, E.

    1991-01-01

    This course reviews the mechanism of interaction between ionizing radiation and a silicon oxide type dielectric, in particular the effect of electron-hole pairs creation in the material. Then effects of cumulated dose on electronic components and especially in MOS technology are examined. Finally methods hardening of these components are exposed. 93 refs

  1. Downstream cumulative effects of land use on freshwater communities

    Science.gov (United States)

    Kuglerová, L.; Kielstra, B. W.; Moore, D.; Richardson, J. S.

    2015-12-01

    Many streams and rivers are subject to disturbance from intense land use such as urbanization and agriculture, and this is especially obvious for small headwaters. Streams are spatially organized into networks where headwaters represent the tributaries and provide water, nutrients, and organic material to the main stems. Therefore perturbations within the headwaters might be cumulatively carried on downstream. Although we know that the disturbance of headwaters in urban and agricultural landscapes poses threats to downstream river reaches, the magnitude and severity of these changes for ecological communities is less known. We studied stream networks along a gradient of disturbance connected to land use intensity, from urbanized watersheds to watersheds placed in agricultural settings in the Greater Toronto Area. Further, we compared the patterns and processes found in the modified watershed to a control watershed, situated in a forested, less impacted landscape. Preliminary results suggest that hydrological modifications (flash floods), habitat loss (drainage and sewer systems), and water quality issues of small streams in urbanized and agricultural watersheds represent major disturbances and threats for aquatic and riparian biota on local as well as larger spatial scales. For example, communities of riparian plants are dominated by species typical of the land use on adjacent uplands as well as the dominant land use on the upstream contributing area, instead of riparian obligates commonly found in forested watersheds. Further, riparian communities in disturbed environments are dominated by invasive species. The changes in riparian communities are vital for various functions of riparian vegetation. Bank erosion control is suppressed, leading to severe channel transformations and sediment loadings in urbanized watersheds. Food sources for instream biota and thermal regimes are also changed, which further triggers alterations of in-stream biological communities

  2. Radiation Effects in M and NEMS

    Science.gov (United States)

    2016-03-31

    electrical basis of operation of M&NEM structures? In particular, cumulative damage by non - ionizing energy loss can, in principle, alter the... Radiation Effects in M&NEMS Michael Alles, Kirill Bolotin, Alex Zettl, Brian Homeijer, Jim Davidson, Ronald Schrimpf, Robert Reed, Dan Fleetwood...understanding radiation effects on the relevant properties of the constituent materials and structures, particularly advanced 2D materials, and the

  3. Biweekly list of papers on radiation chemistry and photochemistry. Annual cumulation with keyword and author indexes. Volume 16. 1983

    International Nuclear Information System (INIS)

    Carmichael, I.C.; Helman, W.P.; Hug, G.L.; Ross, A.B.

    1983-01-01

    The Biweekly List of Papers on Radiation Chemistry and Photochemistry is a current-awareness service published by the Radiation Chemistry Data Center (RCDC), with special emphasis on the kinetics and other properties of transient ions, radicals, and excited species. Papers are included on the radiation chemistry and photochemistry of organic and inorganic systems, biological molecules and polymers, with references to ESR and luminescence studies. Complete coverage is attempted only for those studies which are initiated by light or ionizing radiation, and which provide quantitative physical chemical data such as quantum yields, specific rates, G values, etc. No attempt is made to cover topics such as mechanistic and preparative photochemistry, photosynthesis, photography, and irradiation of metals. The references listed herein are obtained from scanning about 60 current journals as well as Chemical Abstracts, INIS Atomindex and several other publications listing current references. The reference lists, which are issued biweekly, are cumulated annually with the addition of keyword and author indexes. Indexed cumulations were published semiannually for Vol. 4-6 (1971-73) and are published annually for Vol. 7+ (1974+); back copies are available from the National Technical Information Service (NTIS)

  4. Family Resources and Effects on Child Behavior Problem Interventions: A Cumulative Risk Approach.

    Science.gov (United States)

    Tømmerås, Truls; Kjøbli, John

    2017-01-01

    Family resources have been associated with health care inequality in general and with social gradients in treatment outcomes for children with behavior problems. However, there is limited evidence concerning cumulative risk-the accumulation of social and economic disadvantages in a family-and whether cumulative risk moderates the outcomes of evidence-based parent training interventions. We used data from two randomized controlled trials evaluating high-intensity ( n  = 137) and low-intensity ( n  = 216) versions of Parent Management Training-Oregon (PMTO) with a 50:50 allocation between participants receiving PMTO interventions or regular care. A nine-item family cumulative risk index tapping socioeconomic resources and parental health was constructed to assess the family's exposure to risk. Autoregressive structured equation models (SEM) were run to investigate whether cumulative risk moderated child behaviors at post-treatment and follow-up (6 months). Our results showed opposite social gradients for the treatment conditions: the children exposed to cumulative risk in a pooled sample of both PMTO groups displayed lower levels of behavior problems, whereas children with identical risk exposures who received regular care experienced more problems. Furthermore, our results indicated that the social gradients differed between PMTO interventions: children exposed to cumulative risk in the low-intensity (five sessions) Brief Parent Training fared equally well as their high-resource counterparts, whereas children exposed to cumulative risk in the high-intensity PMTO (12 sessions) experienced vastly better treatment effects. Providing evidence-based parent training seem to be an effective way to counteract health care inequality, and the more intensive PMTO treatment seemed to be a particularly effective way to help families with cumulative risk.

  5. Radiation effects at ISABELLE

    International Nuclear Information System (INIS)

    Sanger, P.A.; Danby, G.T.

    1975-01-01

    Shielding, radiation damage, and radiation heating at the planned ISABELLE storage rings were considered. Radiation shielding studies were reviewed and were found to be adequate for present day dosage limits. Radiation damage could be encountered in some extreme cases, but is not expected to limit the performance of the superconducting magnets. Experiments to study the effect of radiation heating on actual magnets are recommended

  6. Acute and Cumulative Effects of Unmodified 50-nm Nano-ZnO on Mice.

    Science.gov (United States)

    Kong, Tao; Zhang, Shu-Hui; Zhang, Ji-Liang; Hao, Xue-Qin; Yang, Fan; Zhang, Cai; Yang, Zi-Jun; Zhang, Meng-Yu; Wang, Jie

    2018-01-02

    Nanometer zinc oxide (nano-ZnO) is widely used in diverse industrial and agricultural fields. Due to the extensive contact humans have with these particles, it is crucial to understand the potential effects that nano-ZnO have on human health. Currently, information related to the toxicity and mechanisms of nano-ZnO is limited. The aim of the present study was to investigate acute and cumulative toxic effects of 50-nm unmodified ZnO in mice. This investigation will seek to establish median lethal dose (LD50), a cumulative coefficient, and target organs. The acute and cumulative toxicity was investigated by Karber's method and via a dose-increasing method, respectively. During the experiment, clinical signs, mortality, body weights, hematology, serum biochemistry, gross pathology, organ weight, and histopathology were examined. The LD50 was 5177-mg/kg·bw; the 95% confidence limits for the LD50 were 5116-5238-mg/kg·bw. It could be concluded that the liver, kidney, lung, and gastrointestinal tract were target organs for the 50-nm nano-ZnO acute oral treatment. The cumulative coefficient (K) was 1.9 which indicated that the cumulative toxicity was apparent. The results also indicated that the liver, kidney, lung, and pancrea were target organs for 50-nm nano-ZnO cumulative oral exposure and might be target organs for subchronic and chronic toxicity of oral administered 50-nm ZnO.

  7. Assessing the cumulative environmental effects of marine renewable energy developments: Establishing common ground.

    Science.gov (United States)

    Willsteed, Edward; Gill, Andrew B; Birchenough, Silvana N R; Jude, Simon

    2017-01-15

    Assessing and managing the cumulative impacts of human activities on the environment remains a major challenge to sustainable development. This challenge is highlighted by the worldwide expansion of marine renewable energy developments (MREDs) in areas already subject to multiple activities and climate change. Cumulative effects assessments in theory provide decision makers with adequate information about how the environment will respond to the incremental effects of licensed activities and are a legal requirement in many nations. In practise, however, such assessments are beset by uncertainties resulting in substantial delays during the licensing process that reduce MRED investor confidence and limit progress towards meeting climate change targets. In light of these targets and ambitions to manage the marine environment sustainably, reducing the uncertainty surrounding MRED effects and cumulative effects assessment are timely and vital. This review investigates the origins and evolution of cumulative effects assessment to identify why the multitude of approaches and pertinent research have emerged, and discusses key considerations and challenges relevant to assessing the cumulative effects of MREDs and other activities on ecosystems. The review recommends a shift away from the current reliance on disparate environmental impact assessments and limited strategic environmental assessments, and a move towards establishing a common system of coordinated data and research relative to ecologically meaningful areas, focussed on the needs of decision makers tasked with protecting and conserving marine ecosystems and services. Copyright © 2016. Published by Elsevier B.V.

  8. Radiation effects and radiation risks

    International Nuclear Information System (INIS)

    Lengfelder, E.; Forst, D.; Feist, H.; Pratzel, H.

    1988-01-01

    The book presents the facts and the principles of assessment and evaluation of biological radiation effects in general and also with particular reference to the reactor accident of Chernobyl, reviewing the consequences and the environmental situation on the basis of current national and international literature, including research work by the authors. The material compiled in this book is intended especially for physicians, but will also prove useful for persons working in the public health services, in administration, or other services taking care of people. The authors tried to find an easily comprehensible way of presenting and explaining the very complex processes and mechanisms of biological radiation effects and carcinogenesis, displaying the physical primary processes and the mechanisms of the molecular radiation effects up to the effects of low-level radiation, and present results of comparative epidemiologic studies. This section has been given considerable space, in proportion to its significance. It also contains literature references for further reading, offering more insight and knowledge of aspects of special subject fields. The authors also present less known results and data and discuss them against the background of well-known research results and approaches. Apart from the purpose of presenting comprehensive information, the authors intend to give an impact for further thinking about the problems, and helpful tools for independent decisions and action on the basis of improved insight and assessment, and in this context particularly point to the problems induced by the Chernobyl reactor accident. (orig./MG) With 8 maps in appendix [de

  9. Overexploitation and cumulative drought trend effect on Ras El Ain ...

    Indian Academy of Sciences (India)

    Boulos Abou Zakhem

    2017-10-06

    Oct 6, 2017 ... development of sustainable water resources management program to reduce long-term drought risks, ... Anatolian mountain chain at >1000 m ASL (Turk- ... due to climatic change effect by global warming. ... supply levels.

  10. Relationship of cumulative low-level dose of ionizing radiation on human eye lens and occurrence of cataract

    International Nuclear Information System (INIS)

    Deolalikar, Raghavendra

    2015-01-01

    International Commission on Radiological Protection (ICRP), issued a statement on Tissue Reaction, lowering the equivalent dose limit for eye lens for occupational exposure to 20 mSv per year. With a view to determine presence of any relationship between the cumulative low-level occupational radiation dose to the eye lens and occurrence of cataract, departmental records of the annual medical examination of employees of Narora Atomic Power Plant were examined along with the NAPS eye camps and surgical records of the employees. Analysis of the data showed no demonstrable definite relationship between the two. The analysis of the data and the observations are discussed in this paper. (author)

  11. 激光穴位照射佐剂性关节炎大鼠的生物效应累积及其镇痛疗效观察%Observations on the Cumulative Biological Effect of Acupoint Laser Radiation and Its Analgesic Effect in Adjuvant Arthritis Rats

    Institute of Scientific and Technical Information of China (English)

    马力佳; 杨华元

    2014-01-01

    光穴位照射治疗后,AA 大鼠相关血清细胞因子均在治疗出现转折点后呈缓慢增长或者下降趋势,即体现了激光照射治疗具有抛物线特征,说明随激光照射时长的增加,激光生物效应的产生累积,提示在激光治疗过程中要重视累积作用。%Objective To explore the mechanism of the cumulative biological effect of acupoint laser radiation and investigate its analgesic effect by comparing the therapeutic effects of semiconductor laser radiation versus acupuncture at point Zusanli(ST36) in acute adjuvant arthritis rats and to provide the experiment-based theoretical foundation and basis for the course of treatment of acute arthritis pain by clinical use of semiconductor laser. Method A rat model of AA was made by subcutaneous injection of complete Freund's adjuvant into rat toe. Eighty rats were randomly allocated to eight groups:model, blank, three-day laser radiation, five-day laser radiation, seven-day laser radiation, three-day acupuncture, five-day acupuncture and seven-day acupuncture treatment groups, 10 rats each. The three laser groups separately received 650 nm semiconductor laser radiation. The three acupuncture groups separately received acupuncture with a filiform needle at point Zusanli(ST36) on the inflammation-affected side. Rat general condition, body weight, pain threshold value and ankle swelling degree were observed. Serum inflammatory factors IL-1、TNF-αand IFN-γcontents were measured by ELISA. Result There were statistically significant posttreatment differences in body weight, joint swelling degree and pain threshold between the laser treatment and acupuncture treatment groups of rats (P<0.05). There was a statistically significant post-treatment difference in joint swelling degree between three-day laser, five-day laser and seven-day laser treatment groups (P<0.05). Pain threshold was lowest at five days after treatment and increased somewhat at seven days after treatment in both the three-day laser and three

  12. Cumulative effects in inflation with ultra-light entropy modes

    Energy Technology Data Exchange (ETDEWEB)

    Achúcarro, Ana; Atal, Vicente [Instituut-Lorentz for Theoretical Physics, Universiteit Leiden, 2333 CA Leiden (Netherlands); Germani, Cristiano [Institut de Ciéncies del Cosmos, Universitat de Barcelona, Martí i Franqués 1, 08028 Barcelona (Spain); Palma, Gonzalo A., E-mail: achucar@lorentz.leidenuniv.nl, E-mail: vicente.atal@icc.ub.edu, E-mail: germani@icc.ub.edu, E-mail: gpalmaquilod@ing.uchile.cl [Grupo de Cosmología y Astrofísica Teórica, Departamento de Física, FCFM, Universidad de Chile, Blanco Encalada 2008, Santiago (Chile)

    2017-02-01

    In multi-field inflation one or more non-adiabatic modes may become light, potentially inducing large levels of isocurvature perturbations in the cosmic microwave background. If in addition these light modes are coupled to the adiabatic mode, they influence its evolution on super horizon scales. Here we consider the case in which a non-adiabatic mode becomes approximately massless (''ultralight') while still coupled to the adiabatic mode, a typical situation that arises with pseudo-Nambu-Goldstone bosons or moduli. This ultralight mode freezes on super-horizon scales and acts as a constant source for the curvature perturbation, making it grow linearly in time and effectively suppressing the isocurvature component. We identify a Stückelberg-like emergent shift symmetry that underlies this behavior. As inflation lasts for many e -folds, the integrated effect of this source enhances the power spectrum of the adiabatic mode, while keeping the non-adiabatic spectrum approximately untouched. In this case, towards the end of inflation all the fluctuations, adiabatic and non-adiabatic, are dominated by a single degree of freedom.

  13. The effect of cultural interaction on cumulative cultural evolution.

    Science.gov (United States)

    Nakahashi, Wataru

    2014-07-07

    Cultural transmission and cultural evolution are important for animals, especially for humans. I developed a new analytical model of cultural evolution, in which each newborn learns cultural traits from multiple individuals (exemplars) in parental generation, individually explores around learned cultural traits, judges the utility of known cultural traits, and adopts a mature cultural trait. Cultural evolutionary speed increases when individuals explore a wider range of cultural traits, accurately judge the skill level of cultural traits (strong direct bias), do not strongly conform to the population mean, increase the exploration range according to the variety of socially learned cultural traits (condition dependent exploration), and make smaller errors in social learning. Number of exemplars, population size, similarity of cultural traits between exemplars, and one-to-many transmission have little effect on cultural evolutionary speed. I also investigated how cultural interaction between two populations with different mean skill levels affects their cultural evolution. A population sometimes increases in skill level more if it encounters a less skilled population than if it does not encounter anyone. A less skilled population sometimes exceeds a more skilled population in skill level by cultural interaction between both populations. The appropriateness of this analytical method is confirmed by individual-based simulations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Cumulative effective dose associated with computed tomography examinations in adolescent trauma patients.

    Science.gov (United States)

    Choi, Seung Joon; Kim, Eun Young; Kim, Hyung Sik; Choi, Hye-Young; Cho, Jinseong; Yang, Hyuk Jun; Chung, Yong Eun

    2014-07-01

    The aims of this study were to analyze cumulative effective dose (cED) and to assess lifetime attributable risk (LAR) of cancer due to radiation exposure during computed tomography (CT) examinations in adolescent trauma patients. Between January 2010 and May 2011, the adolescent patients with trauma were enrolled in this study. Numbers of CT examinations and body regions examined were collated, and cEDs were calculated using dose-length product values and conversion factors. Lifetime attributable risk for cancer incidence and cancer-associated mortality were quantified based on the studies of survivors of the atomic bombs on Japan. Data were stratified according to severity of trauma: minor trauma, injury severity score of less than 16; and major trauma, injury severity score of 16 or greater. A total of 698 CT scans were obtained on the following regions of 484 adolescent patients: head CT, n = 647; rest of the body, n = 41; and thorax, n = 10. Mean cED per patient was 3.4 mSv, and mean LARs for cancer incidence and mortality were 0.05% and 0.02%, respectively. The majority of patients (98.4%) experienced minor trauma, and their mean cED and LARs for cancer incidence and mortality (3.0 mSv and 0.04% and 0.02%, respectively) were significantly lower than those of patients with major trauma (24.3 mSv and 0.31% and 0.15%, respectively, all P values trauma was found to be relatively low in adolescent patients. However, adolescent patients with major trauma were exposed to a substantial amount of radiation during multiple CT examinations.

  15. Predicting the cumulative effect of multiple disturbances on seagrass connectivity.

    Science.gov (United States)

    Grech, Alana; Hanert, Emmanuel; McKenzie, Len; Rasheed, Michael; Thomas, Christopher; Tol, Samantha; Wang, Mingzhu; Waycott, Michelle; Wolter, Jolan; Coles, Rob

    2018-03-15

    The rate of exchange, or connectivity, among populations effects their ability to recover after disturbance events. However, there is limited information on the extent to which populations are connected or how multiple disturbances affect connectivity, especially in coastal and marine ecosystems. We used network analysis and the outputs of a biophysical model to measure potential functional connectivity and predict the impact of multiple disturbances on seagrasses in the central Great Barrier Reef World Heritage Area (GBRWHA), Australia. The seagrass networks were densely connected, indicating that seagrasses are resilient to the random loss of meadows. Our analysis identified discrete meadows that are important sources of seagrass propagules and that serve as stepping stones connecting various different parts of the network. Several of these meadows were close to urban areas or ports and likely to be at risk from coastal development. Deep water meadows were highly connected to coastal meadows and may function as a refuge, but only for non-foundation species. We evaluated changes to the structure and functioning of the seagrass networks when one or more discrete meadows were removed due to multiple disturbance events. The scale of disturbance required to disconnect the seagrass networks into two or more components was on average >245 km, about half the length of the metapopulation. The densely connected seagrass meadows of the central GBRWHA are not limited by the supply of propagules; therefore, management should focus on improving environmental conditions that support natural seagrass recruitment and recovery processes. Our study provides a new framework for assessing the impact of global change on the connectivity and persistence of coastal and marine ecosystems. Without this knowledge, management actions, including coastal restoration, may prove unnecessary and be unsuccessful. © 2018 John Wiley & Sons Ltd.

  16. Cumulative ecological and socioeconomic effects of forest policies in coastal Oregon.

    Science.gov (United States)

    T.A. Spies; K.N. Johnson; K.M. Burnett; J.L. Ohmann; B.C. McComb; G.H. Reeves; P. Bettinger; J.D. Kline; B. Garber-Yonts

    2007-01-01

    Forest biodiversity policies in multiownership landscapes are typically developed in an uncoordinated fashion with little consideration of their interactions or possible unintended cumulative effects. We conducted an assessment of some of the ecological and socioeconomic effects of recently enacted forest management policies in the 2.3-million-ha Coast Range...

  17. Practical use of the fertigation control based on cumulative solar radiation to decrease the nitrate concentration in spinach [Spinacia oleracea] grown in the greenhouse

    International Nuclear Information System (INIS)

    Shinohara, Y.; Tsukagoshi, S.; Hayashi, N.; Maruo, T.; Hohjo, M.

    2007-01-01

    Spinach plants (Spinacia oleracea L.) were grown in a greenhouse using fertigation based on cumulative solar radiation, and effects on plant growth, nitrate concentration in the leaves, and nitrate utilization/application ratio were studied. The relation of water and NO3-N absorption to cumulative solar radiation was initially determined in hydroponically grown spinach, then the stepwise fertigation program was set to 1.0, 1.2 and 1.4 times the standard quantity. With 1.2 fertigation treatment, plant growth and leaf color did not differ from those of plants cultivated by conventional soil culture. Total nitrate supplied to the soil under fertigation treatment were about half of that at soil culture. The nitrate utilization/application ratio was increased from 44% in soil culture to 82% under fertigation treatment. The nitrate concentration in spinach leaves under fertigation treatments tended to be lower compared to those under soil culture. In addition, the production of spinach with lower nitrate and without effects on growth seemed to be feasible by the withdrawal of NO3-N in the drip solution for several days before harvest

  18. Incorporating cumulative effects into environmental assessments of mariculture: Limitations and failures of current siting methods

    International Nuclear Information System (INIS)

    King, Sarah C.; Pushchak, Ronald

    2008-01-01

    Assessing and evaluating the cumulative impacts of multiple marine aquaculture facilities has proved difficult in environmental assessment. A retrospective review of 23 existing mariculture farms in southwestern New Brunswick was conducted to determine whether cumulative interactions would have justified site approvals. Based on current scientific evidence of cumulative effects, six new criteria were added to a set of far-field impacts and other existing criteria were expanded to include regional and cumulative environmental impacts in Hargrave's [Hargrave BT. A traffic light decision system for marine finfish aquaculture siting. Ocean Coast Manag 2002; 45:215-35.] Traffic Light Decision Support System (DSS) presently used in Canadian aquaculture environmental assessments. Before mitigation, 19 of the 23 sites failed the amended set of criteria and after considering mitigation, 8 sites failed. Site and ecosystem indices yielded varying site acceptability scores; however, many sites would not have been approved if siting decisions had been made within a regional management framework and cumulative impact criteria were considered in the site evaluation process

  19. Detection limits by EPR spectroscopy of cumulated doses ionizing radiations in molluscs shells

    International Nuclear Information System (INIS)

    Ostrowski, K.; Burlinska, G.; Dziedzic-Goclawska, A.; Stachowicz, W.; Michalik, J.; Sadlo, J.

    1997-01-01

    The exposure of waters to ionizing radiation from radionuclides stored in concrete containers or freed in nuclear accidents or underwater eruption might be difficult to be proved, when currents, rains, exchange of water displace sand soils or rocks in the bottom. Ionizing radiation evokes stable paramagnetic centers in the crystalline lattice of mineral components in bones as well as in exoskeletons of most molluscs, which are detected by the EPR spectroscopy and could be used as an indicator of the exposure to the action of radiation during prolonged period of time. (authors)

  20. Radiation effects in vitreous and devitrified simulated waste glass

    International Nuclear Information System (INIS)

    Weber, W.J.; Turcotte, R.P.; Bunnell, L.R.; Roberts, F.P.; Westsik, J.H. Jr.

    1979-01-01

    The long-term radiation stability of vitreous and partially devitrified forms of high-level waste glass was investigated in accelerated experiments by 266 Cm doping. The effects of radiation on microstructure, phase behavior, density, impact strength, stored energy, and leachability are reported to a cumulative radiation dose of 5 x 10 18 α decays/cm 3 . This dose produces saturation of radiation effects in most properties. 4 figures

  1. A simplified model for cumulative damage with interaction effect for creep loading

    International Nuclear Information System (INIS)

    Gomuc, R.; Bui-Quoc, T.; Biron, A.

    1989-01-01

    This paper explains that the basic creep-rupture behavior of a material at high temperature is obtained with constant stresses under isothermal conditions. Structural components operating at high temperature are, however, usually subjected to fluctuations of stresses and/or temperatures. Experimental conditions cannot cover all possible combinations of these parameters and, in addition, systematic investigations on cumulative creep damage are very limited due to long-term testing. The authors suggest that there is a need to establish a reliable procedure for evaluating the cumulative creep damage effect under non-steady stresses and temperatures

  2. The cumulative effect of air pollutants on the acute exacerbation of COPD in Shanghai, China.

    Science.gov (United States)

    Sun, Xian Wen; Chen, Pei Li; Ren, Lei; Lin, Ying Ni; Zhou, Jian Ping; Ni, Lei; Li, Qing Yun

    2018-05-01

    Epidemiologic studies have shown the effect of air pollutants on acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, little is known regarding the dose-response relationship. This study aimed to investigate the cumulative effect of air pollutants on AECOPD. We collected 101 patients with AECOPD from November 2010 through August 2011 in Shanghai. Multiple logistic regression was used to estimate associations between air pollutants and AECOPD. Poisson regression was then applied to determine the cumulative effect of air pollutants including particulate matter 10 (PM10), PM2.5, nitrogen dioxide (NO 2 ), sulphur dioxide (SO 2 ) and ozone (O 3 ) on AECOPD, of which the seasonal variation was further explored. The monthly episodes of AECOPD were associated with the concentrations of PM2.5 (r=0.884, peffect in cold season, whereas 7days in warm season. The RR for AECOPD for per 10μg/m 3 increment in NO 2 was 1.07, with a 5-day cumulative effect without seasonal variation. High consecutive levels of PM2.5 and NO 2 increase the risk of developing AECOPD. Cumulative effect of PM2.5 and NO 2 appears before the exacerbation onset. These gradations were more evident in the PM2.5 during different seasons. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Cumulative effects assessment in Canada: an agenda for action and research

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, E.B.; Chan, Y.-H.; Peterson, N.M.; Constable, G.A.; Caton, R.B.; Davis, C.S.; Wallace, R.R.; Yarranton, G.A.

    1987-01-01

    This review of cumulative environmental effects assessment in Canada identified 13 sets of issues that are considered to be of particular significance to Canadians over the next decade or two. They are: long-range transport of air pollutants; urban air quality and airshed saturation, mobilization of persistent or bioaccumulated substances, climatic modification, land occupation by man-made features, habitat alienation and fragmentation, soil losses, effects of agricultural chemicals, groundwater supply reduction and contamination, increased sediment, chemical and thermal loading of freshwater and marine habitats, accelerating rates of renewable resource harvesting, and long-term containment and disposal of toxic wastes. There is a diverse set of examples in which cumulative effects have been recognized and brought under control and management, and the scientific and institutional factors that promoted a successful approach are summarized. It was confirmed that there are well-defined limitations in the degree to which project referrals and project-specific environmental impact assessments can be adapted to manage cumulative effects successfully. In general, this review confirmed the hypothesis that current approaches for both scientific analyses and institutional arrangements to manage cumulative effects remain inadequately developed in Canada. To address this weakness, action is required on improving links between ecosystems, research, and management. Recommendations are made and a research agenda is presented. 171 refs., 5 figs., 2 tabs.

  4. Looking up, down, and sideways: Reconceiving cumulative effects assessment as a mindset

    Energy Technology Data Exchange (ETDEWEB)

    Sinclair, A. John, E-mail: jsincla@umanitoba.ca [Natural Resources Institute, University of Manitoba, Winnipeg, MB R3T 2N2 (Canada); Doelle, Meinhard, E-mail: mdoelle@dal.ca [Marine & Environmental Law Institute, Dalhousie University, Schulich School of Law, Dalhousie University, 6061 University Ave., Halifax, Nova Scotia B3H 4R2 (Canada); Duinker, Peter N., E-mail: peter.duinker@dal.ca [School for Resource and Environmental Studies, Dalhousie University, 6100 University Ave., Halifax, Nova Scotia B3H 4R2 (Canada)

    2017-01-15

    Despite all the effort that has gone into defining, researching and establishing best practices for cumulative effects assessment (CEA), understanding remains weak and practice wanting. At one extreme of implementation, CEA can be described as merely an irritant to the completion of a project-specific environmental assessment (EA). At the other extreme, the conceptual view is that all effects in EA should be deemed cumulative unless demonstrated otherwise. Our purpose here is to consider how we might reconceive CEA as a mindset that is at the heart of absolutely every assessment of valued ecosystem component (VEC) to ensure that we understand the relative contributions of various stressors and can decide when cumulative effects may foreclose future activities due to impacts on VECs. Conceptually, we ground the CEA mindset in the context of three lenses that must all be functioning and working together for the mindset to be operative: a technical lens; a law and policy lens; and a participatory lens. Our arguments are based on a review of the CEA, strategic effects assessment (SEA) and regional effects assessment literatures, an examination and consideration of Canadian EA and SEA case practice, and our combined professional experiences. Through using the Bay of Fundy in Canada as a case example, we establish the concept of the CEA mindset and an approach for moving forward with implementation. - Highlights: • Conceptualization of cumulative effects assessment as a mindset. • Elaboration of technical, law and policy and participation lenses critical to CEA • Coordination and integration of cumulative effects for valued ecosystem components • Application in Bay of Fundy ecosystem and terrestrial watershed.

  5. Evaluating long-term cumulative hydrologic effects of forest management: a conceptual approach

    Science.gov (United States)

    Robert R. Ziemer

    1992-01-01

    It is impractical to address experimentally many aspects of cumulative hydrologic effects, since to do so would require studying large watersheds for a century or more. Monte Carlo simulations were conducted using three hypothetical 10,000-ha fifth-order forested watersheds. Most of the physical processes expressed by the model are transferable from temperate to...

  6. Effect of cumulative strain on texture characteristics during wire drawing of eutectoid steels

    International Nuclear Information System (INIS)

    Yang, F.; Ma, C.; Jiang, J.Q.; Feng, H.P.; Zhai, S.Y.

    2008-01-01

    The texture characteristics associated with plastic deformation of Fe-C steels near-eutectoid composition during a continuous cold drawing process were thoroughly investigated by orientation distribution function analysis based on X-ray diffraction. The effect of cumulative drawing strains on the fiber texture in drawn hypereutectoid and hypoeutectoid steel wires was discussed

  7. Cumulative Effects of Exposure to Violence on Posttraumatic Stress in Palestinian and Israeli Youth

    Science.gov (United States)

    Dubow, Eric F.; Boxer, Paul; Huesmann, L. Rowell; Landau, Simha; Dvir, Shira; Shikaki, Khalil; Ginges, Jeremy

    2012-01-01

    We examine cumulative and prospective effects of exposure to conflict and violence across four contexts (ethnic-political, community, family, school) on posttraumatic stress (PTS) symptoms in Palestinian and Israeli youth. Interviews were conducted with 600 Palestinian and 901 Israeli (Jewish and Arab) children (ages 8, 11, and 14) and their…

  8. Quantitative methods for analysing cumulative effects on fish migration success: a review.

    Science.gov (United States)

    Johnson, J E; Patterson, D A; Martins, E G; Cooke, S J; Hinch, S G

    2012-07-01

    It is often recognized, but seldom addressed, that a quantitative assessment of the cumulative effects, both additive and non-additive, of multiple stressors on fish survival would provide a more realistic representation of the factors that influence fish migration. This review presents a compilation of analytical methods applied to a well-studied fish migration, a more general review of quantitative multivariable methods, and a synthesis on how to apply new analytical techniques in fish migration studies. A compilation of adult migration papers from Fraser River sockeye salmon Oncorhynchus nerka revealed a limited number of multivariable methods being applied and the sub-optimal reliance on univariable methods for multivariable problems. The literature review of fisheries science, general biology and medicine identified a large number of alternative methods for dealing with cumulative effects, with a limited number of techniques being used in fish migration studies. An evaluation of the different methods revealed that certain classes of multivariable analyses will probably prove useful in future assessments of cumulative effects on fish migration. This overview and evaluation of quantitative methods gathered from the disparate fields should serve as a primer for anyone seeking to quantify cumulative effects on fish migration survival. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.

  9. Unique versus cumulative effects of physical and sexual assault on patterns of adolescent substance use

    NARCIS (Netherlands)

    Charak, R.; Koot, H.M.; Dvorak, R.D.; Elklit, A.; Elhai, J.D.

    2015-01-01

    The present study assessed the unique versus cumulative effects of physical and sexual assault, on patterns of substance-use in adolescents. It was hypothesized that experiencing a single assault (physical or sexual) when compared with exposure to both physical and sexual assault would be more

  10. Space radiation effects

    International Nuclear Information System (INIS)

    Li Shiqing; Yan Heping

    1995-01-01

    The authors briefly discusses the radiation environment in near-earth space and it's influences on material, and electronic devices using in space airship, also, the research developments in space radiation effects are introduced

  11. Radiation effects in space

    International Nuclear Information System (INIS)

    Fry, R.J.M.

    1986-01-01

    The paper discusses the radiation environment in space that astronauts are likely to be exposed to. Emphasis is on proton and HZE particle effects. Recommendations for radiation protection guidelines are presented

  12. Fitness costs of increased cataract frequency and cumulative radiation dose in natural mammalian populations from Chernobyl.

    Science.gov (United States)

    Lehmann, Philipp; Boratyński, Zbyszek; Mappes, Tapio; Mousseau, Timothy A; Møller, Anders P

    2016-01-27

    A cataract is a clouding of the lens that reduces light transmission to the retina, and it decreases the visual acuity of the bearer. The prevalence of cataracts in natural populations of mammals, and their potential ecological significance, is poorly known. Cataracts have been reported to arise from high levels of oxidative stress and a major cause of oxidative stress is ionizing radiation. We investigated whether elevated frequencies of cataracts are found in eyes of bank voles Myodes glareolus collected from natural populations in areas with varying levels of background radiation in Chernobyl. We found high frequencies of cataracts in voles collected from different areas in Chernobyl. The frequency of cataracts was positively correlated with age, and in females also with the accumulated radiation dose. Furthermore, the number of offspring in female voles was negatively correlated with cataract severity. The results suggest that cataracts primarily develop as a function of ionizing background radiation, most likely as a plastic response to high levels of oxidative stress. It is therefore possible that the elevated levels of background radiation in Chernobyl affect the ecology and fitness of local mammals both directly through, for instance, reduced fertility and indirectly, through increased cataractogenesis.

  13. Cumulative genetic damage in children exposed to preconception and intrauterine radiation

    International Nuclear Information System (INIS)

    Bross, I.D.; Natarajan, N.

    1980-01-01

    Using a mathematical model and newly developed computer software, the data from the Tri-State Leukemia Survey involving different combinations of radiation exposures to the father and mother prior to conception and to the mother during pregnancy were analyzed. The hypothesis that radiation exposure produces genetic damage which may be expressed in the child both as indicator disease and as leukemia was tested. The genetic damage was estimated in terms of the proportion affected by a given exposure. The relative risk of leukemia and certain other indicator diseases among those affected could then be estimated. The results show that there are at least two distinguishable risk groups, one group with lower (one or two exposures); and the other group with higher (two or three) radiation exposures

  14. Influence of explosive sharge treating on armour piercing of cumulative jet by γ-radiation

    International Nuclear Information System (INIS)

    Grishkin, A.M.; Davydov, V.Yu.; Feodoritov, M.I.; Mikhajlova, T.N.; Levshina, Yu.A.

    1992-01-01

    The paper reviews a method for changing physical structure of an explosive charge (EC) - exposure of the TNT-PDX cast ECs were used for this purpose at 40/60 ratios. It is shown that impact of γ-radiation on the shaped charge results in a deeper armour pierciny due to improved EC detonation characteristics in narrow sections of the charge

  15. The Contribution of Project Environmental Assessment to Assessing and Managing Cumulative Effects: Individually and Collectively Insignificant?

    Science.gov (United States)

    Noble, Bram; Liu, Jialang; Hackett, Paul

    2017-04-01

    This paper explores the opportunities and constraints to project-based environmental assessment as a means to support the assessment and management of cumulative environmental effects. A case study of the hydroelectric sector is used to determine whether sufficient information is available over time through project-by-project assessments to support an adequate understanding of cumulative change. Results show inconsistency from one project to the next in terms of the components and indicators assessed, limited transfer of baseline information between project assessments over time, and the same issues and concerns being raised by review panels-even though the projects reviewed are operating in the same watershed and operated by the same proponent. Project environmental assessments must be managed, and coordinated, as part of a larger system of impact assessment, if project-by-project assessments are to provide a meaningful forum for learning and understanding cumulative change. The paper concludes with recommendations for improved project-based assessment practice in support of cumulative effects assessment and management.

  16. Biological radiation effects

    International Nuclear Information System (INIS)

    Gomes, R.A.

    1976-01-01

    The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and organs are commented. Referring to delayed radiation effects, carcinogeneses, alterations of life span, effects on growth and development, as well as localized effects, are also discussed [pt

  17. Biological effects of radiation

    International Nuclear Information System (INIS)

    2013-01-01

    This fourth chapter presents: cell structure and metabolism; radiation interaction with biological tissues; steps of the production of biological effect of radiation; radiosensitivity of tissues; classification of biological effects; reversibility, transmissivity and influence factors; pre-natal biological effects; biological effects in therapy and syndrome of acute irradiation

  18. Fitness costs of increased cataract frequency and cumulative radiation dose in natural mammalian populations from Chernobyl

    OpenAIRE

    Lehmann, Philipp; Boraty?ski, Zbyszek; Mappes, Tapio; Mousseau, Timothy A.; M?ller, Anders P.

    2016-01-01

    A cataract is a clouding of the lens that reduces light transmission to the retina, and it decreases the visual acuity of the bearer. The prevalence of cataracts in natural populations of mammals, and their potential ecological significance, is poorly known. Cataracts have been reported to arise from high levels of oxidative stress and a major cause of oxidative stress is ionizing radiation. We investigated whether elevated frequencies of cataracts are found in eyes of bank voles Myodes glare...

  19. Multiple procedures and cumulative individual radiation exposure in interventional cardiology: A long-term retrospective study

    Energy Technology Data Exchange (ETDEWEB)

    Weltermann, Birgitta M.; Rock, Thomas; Berndt, Peter; Viehmann, Anja; Reinders, Sabrina; Gesenhues, Stefan [University of Duisburg-Essen, Institute for General Medicine, University Hospital, Essen (Germany); Brix, Gunnar; Schegerer, Alexander [Federal Office for Radiation Protection, Department of Radiation Protection and Health, Neuherberg (Germany)

    2015-09-15

    Various studies address discrepancies between guideline recommendations for coronary angiographies and clinical practice. While the issue of the appropriateness of recurrent angiographies was studied focusing on the role of the cardiologist, little is known about individual patients' histories and the associated radiation exposures. We analyzed all patients with coronary artery disease (CAD) in an academic teaching practice who underwent at least one angiography with or without intervention between 2004 and 2009. All performed angiographies in these patients were analyzed and rated by three physicians for appropriateness levels according to cardiology guidelines. Typical exposure data from the medical literature were used to estimate individual radiation exposure. In the cohort of 147 patients, a total of 441 procedures were analyzed: between 1981 and 2009, three procedures were performed per patient (range 1-19) on average. Appropriateness ratings were 'high/intermediate' in 71 %, 'low/no' in 27.6 % and data were insufficient for ratings in 1.4 %. Procedures with 'low/no' ratings were associated with potentially avoidable exposures of up to 186 mSv for single patients. Using retrospective data, we exemplify the potential benefit of guideline adherence to decrease patients' radiation exposures. (orig.)

  20. Radiation effects in semiconductors

    CERN Document Server

    2011-01-01

    There is a need to understand and combat potential radiation damage problems in semiconductor devices and circuits. Written by international experts, this book explains the effects of radiation on semiconductor devices, radiation detectors, and electronic devices and components. These contributors explore emerging applications, detector technologies, circuit design techniques, new materials, and innovative system approaches. The text focuses on how the technology is being used rather than the mathematical foundations behind it. It covers CMOS radiation-tolerant circuit implementations, CMOS pr

  1. Higher order net-proton number cumulants dependence on the centrality definition and other spurious effects

    Science.gov (United States)

    Sombun, S.; Steinheimer, J.; Herold, C.; Limphirat, A.; Yan, Y.; Bleicher, M.

    2018-02-01

    We study the dependence of the normalized moments of the net-proton multiplicity distributions on the definition of centrality in relativistic nuclear collisions at a beam energy of \\sqrt{{s}{NN}}=7.7 {GeV}. Using the ultra relativistic quantum molecular dynamics model as event generator we find that the centrality definition has a large effect on the extracted cumulant ratios. Furthermore we find that the finite efficiency for the determination of the centrality introduces an additional systematic uncertainty. Finally, we quantitatively investigate the effects of event-pile up and other possible spurious effects which may change the measured proton number. We find that pile-up alone is not sufficient to describe the data and show that a random double counting of events, adding significantly to the measured proton number, affects mainly the higher order cumulants in most central collisions.

  2. Radiation Therapy Side Effects

    Science.gov (United States)

    Radiation therapy has side effects because it not only kills or slows the growth of cancer cells, it can also affect nearby healthy cells. Many people who get radiation therapy experience fatigue. Other side effects depend on the part of the body that is being treated. Learn more about possible side effects.

  3. Alchemy to reason: Effective use of Cumulative Effects Assessment in resource management

    International Nuclear Information System (INIS)

    Hegmann, George; Yarranton, G.A.

    2011-01-01

    Cumulative Effects Assessment (CEA) is a tool that can be useful in making decisions about natural resource management and allocation. The decisions to be made include those (i) necessary to construct planning and regulatory frameworks to control development activity so that societal goals will be achieved and (ii) whether or not to approve individual development projects, with or without conditions. The evolution of CEA into a more successful tool cannot occur independently of the evolution of decision making processes. Currently progress is painfully slow on both fronts. This paper explores some opportunities to accelerate improvements in decision making in natural resource management and in the utility of CEA as a tool to assist in making such decisions. The focus of the paper is on how to define the public interest by determining what is acceptable.

  4. Cumulative effect of multiple trauma on symptoms of posttraumatic stress disorder, anxiety, and depression in adolescents.

    Science.gov (United States)

    Suliman, Sharain; Mkabile, Siyabulela G; Fincham, Dylan S; Ahmed, Rashid; Stein, Dan J; Seedat, Soraya

    2009-01-01

    Recent literature has indicated that exposure to multiple traumatic events in adults is associated with high levels of posttraumatic stress disorder (PTSD), anxiety, and depression. Against the backdrop of stressful life events and childhood abuse and neglect, we investigated the cumulative effect of multiple trauma exposure on PTSD, anxiety, and depression in an adolescent sample. One thousand one hundred forty 10th-grade learners from 9 Cape Town (South Africa) schools completed questionnaires on stressful life experiences; trauma exposure; and symptoms of anxiety, depression, and PTSD. Our population of interest for this study was adolescents between the ages of 14 and 18 years who had been exposed to serious, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, qualifying traumatic events. The final sample size was thus 922. Rates of trauma exposure, PTSD, depression, and anxiety were high. Controlling for sex, stressful life experiences in the past year, and childhood adversity, we found an effect of cumulative trauma exposure effect on PTSD and depression, with an increase in the number of traumas linearly associated with an increase in symptoms of PTSD (F((4,912)) = 7.60, P cumulative effect on anxiety. Our findings indicate that adolescents exposed to multiple traumas are more likely to experience more severe symptoms of PTSD and depression than those who experience a single event, with this effect independent of childhood adversity and everyday stressful life experiences. Exposure to multiple trauma, however, does not seem to be associated with more severe anxiety symptoms.

  5. Environmental impacts of renewable energy. Geographic Information Systems (GIS) based analysis of cumulative effects

    International Nuclear Information System (INIS)

    Rhoden, Henning

    2015-01-01

    The energy transition and thus turning away from fossil fuels and nuclear energy sources is based on an increased expansion of renewable energies. This expansion mainly take place in nature and the landscape, which conflicts with the objectives of the Federal Nature Conservation Act concerning scenery or the consequences of monoculture cultivation of energy crops. What happens, however, if more than one type of renewables occur compressed in a landscape that is investigated in this work. Result from cumulative effects are extended conflict with the objectives of the Federal Nature Conservation Act or possibly have positive effects can be seen? A ''cumulative effect'' is defined as an additive-synergistic overall effect of all a protected interest of respective impact factors. These arise from one or more projects / plans and influence from a variety of ways. As part of the investigations carried out it is clear that extended conflicts may arise in relation to the objectives of the Federal Nature Conservation Act by cumulative effects of renewable energies. To prevent these conflicts, policies and regulations in the context of spatial planning is necessary to enable a focusing of spatial planning for a sustainable expansion of renewable energy. [de

  6. Cumulative reproductive effects of in utero administration of mixtures of antiandrogens in male SD rats: synergy or additivity?

    Science.gov (United States)

    In 1996 the USEPA was charged under the FQPA to consider the cumulative effects of chemicals in their risk assessments. Our studies were conducted to provide a framework for assessing the cumulative effects of antiandrogens. Toxicants were administered individually or as mixtures...

  7. Cumulative dose 60Co gamma irradiation effects on AlGaN/GaN Schottky diodes and its area dependence

    Science.gov (United States)

    Sharma, Chandan; Laishram, Robert; Rawal, Dipendra Singh; Vinayak, Seema; Singh, Rajendra

    2018-04-01

    Cumulative dose gamma radiation effects on current-voltage characteristics of GaN Schottky diodes have been investigated. The different area diodes have been fabricated on AlGaN/GaN high electron mobility transistor (HEMT) epi-layer structure grown over SiC substrate and irradiated with a dose up to the order of 104 Gray (Gy). Post irradiation characterization shows a shift in the turn-on voltage and improvement in reverse leakage current. Other calculated parameters include Schottky barrier height, ideality factor and reverse saturation current. Schottky barrier height has been decreased whereas reverse saturation current shows an increase in the value post irradiation with improvement in the ideality factor. Transfer length measurement (TLM) characterization shows an improvement in the contact resistance. Finally, diodes with larger area have more variation in the calculated parameters due to the induced local heating effect.

  8. CEAMF study, volume 2 : cumulative effects indicators, thresholds, and case studies : final

    International Nuclear Information System (INIS)

    2003-03-01

    The four types of cumulative effects on the environment are: alteration, loss, and fragmentation of habitat; disturbance; barriers to movement; and direct and indirect mortality. Defining where and how human activities can be continued without irreversible net harm to the environment is part of cumulative effects management. Various land-use and habitat indicators were tested in the Blueberry and Sukunka study areas of British Columbia, to address the environmental effects associated with oil and gas development. As recommended, a tiered threshold approach was used to allow for flexibility in different land management regimes and ecological settings. Success will depend on defining acceptable change, threshold values, standard public database, standard processes to calculate indicator values using the database, and project-specific and cooperative management actions. A pilot study was suggested to test the candidate thresholds and implementation process. The two areas proposed for consideration were the Jedney Enhanced Resource Development Resource Management Zone in the Fort St. John Forest District, and the Etsho Enhanced Resource Development Resource Management Zone in the Fort Nelson Forest District. Both are of interest to the petroleum and forest sectors, and support the woodland caribou, a species which is extremely sensitive to cumulative effects of habitat fragmentation and disturbance. 117 refs., 11 tabs., 39 figs.

  9. Cumulative effects of cascade hydropower stations on total dissolved gas supersaturation.

    Science.gov (United States)

    Ma, Qian; Li, Ran; Feng, Jingjie; Lu, Jingying; Zhou, Qin

    2018-03-01

    Elevated levels of total dissolved gas (TDG) may occur downstream of dams during the spill process. These high levels would increase the incidence of gas bubble disease in fish and cause severe environmental impacts. With increasing numbers of cascade hydropower stations being built or planned, the cumulative effects of TDG supersaturation are becoming increasingly prominent. The TDG saturation distribution in the downstream reaches of the Jinsha River was studied to investigate the cumulative effects of TDG supersaturation resulting from the cascade hydropower stations. A comparison of the effects of the joint operation and the single operation of two hydropower stations (XLD and XJB) was performed to analyze the risk degree to fish posed by TDG supersaturation. The results showed that water with supersaturated TDG generated at the upstream cascade can be transported to the downstream power station, leading to cumulative TDG supersaturation effects. Compared with the single operation of XJB, the joint operation of both stations produced a much higher TDG saturation downstream of XJB, especially during the non-flood discharge period. Moreover, the duration of high TDG saturation and the lengths of the lethal and sub-lethal areas were much higher in the joint operation scenario, posing a greater threat to fish and severely damaging the environment. This work provides a scientific basis for strategies to reduce TDG supersaturation to the permissible level and minimize the potential risk of supersaturated TDG.

  10. Conceptual and methodological challenges to integrating SEA and cumulative effects assessment

    International Nuclear Information System (INIS)

    Gunn, Jill; Noble, Bram F.

    2011-01-01

    The constraints to assessing and managing cumulative environmental effects in the context of project-based environmental assessment are well documented, and the potential benefits of a more strategic approach to cumulative effects assessment (CEA) are well argued; however, such benefits have yet to be clearly demonstrated in practice. While it is widely assumed that cumulative effects are best addressed in a strategic context, there has been little investigation as to whether CEA and strategic environmental assessment (SEA) are a 'good fit' - conceptually or methodologically. This paper identifies a number of conceptual and methodological challenges to the integration of CEA and SEA. Based on results of interviews with international experts and practitioners, this paper demonstrates that: definitions and conceptualizations of CEA are typically weak in practice; approaches to effects aggregation vary widely; a systems perspective lacks in both SEA and CEA; the multifarious nature of SEA complicates CEA; tiering arrangements between SEA and project-based assessment are limited to non-existing; and the relationship of SEA to regional planning remains unclear.

  11. Evaluation of gamma radiation cumulative exposure monitoring system in the Nuclear Technology Development Center (CDTN) with thermoluminescent dosimeters

    Energy Technology Data Exchange (ETDEWEB)

    Domingues, Danieli S.; Barreto, Alberto A.; Siqueira, Gessilane M.; Oliveira, Eugênio M.; Silva, Robson L.; Belo, Luiz Cláudio M., E-mail: danielisilva@ymail.com, E-mail: aab@cdtn.br, E-mail: gessilane.siqueira@cdtn.br, E-mail: emo@cdtn.br, E-mail: rls@cdtn.br, E-mail: lcmb@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2017-07-01

    Cumulative exposure to gamma radiation is monitored at the Nuclear Technology Development Center - CDTN, located on the campus of the Federal University of Minas Gerais in Belo Horizonte - MG, since 1986. This monitoring is part of the Institution's Environmental Monitoring Program. The measurement is carried out through the use of thermoluminescent dosimeters (TLD's), which are placed in the perimeter of the CDTN property, distanced approximately 50 m each other, and at the air sampling stations, totaling 36 sampling points. The TLDs are positioned one meter from the ground, inside a PVC pipe where they remain exposed for a period of approximately three months. The objective of this work is to present and evaluate the results of this monitoring by investigating the dose values of gamma radiation (Dose Equivalent to Photons) obtained. Another important issue presented is about some failures identified in certain periods. There were problems with the sampling methodology and changes were proposed in the shelters to avoid contact of TLDs with excess moisture, which can compromise the results and the equipment of measurement of the thermoluminescence of crystals. The change was made at a sampling point and the results were compared with the historical data in the last 30 years. (author)

  12. Evaluation of gamma radiation cumulative exposure monitoring system in the Nuclear Technology Development Center (CDTN) with thermoluminescent dosimeters

    International Nuclear Information System (INIS)

    Domingues, Danieli S.; Barreto, Alberto A.; Siqueira, Gessilane M.; Oliveira, Eugênio M.; Silva, Robson L.; Belo, Luiz Cláudio M.

    2017-01-01

    Cumulative exposure to gamma radiation is monitored at the Nuclear Technology Development Center - CDTN, located on the campus of the Federal University of Minas Gerais in Belo Horizonte - MG, since 1986. This monitoring is part of the Institution's Environmental Monitoring Program. The measurement is carried out through the use of thermoluminescent dosimeters (TLD's), which are placed in the perimeter of the CDTN property, distanced approximately 50 m each other, and at the air sampling stations, totaling 36 sampling points. The TLDs are positioned one meter from the ground, inside a PVC pipe where they remain exposed for a period of approximately three months. The objective of this work is to present and evaluate the results of this monitoring by investigating the dose values of gamma radiation (Dose Equivalent to Photons) obtained. Another important issue presented is about some failures identified in certain periods. There were problems with the sampling methodology and changes were proposed in the shelters to avoid contact of TLDs with excess moisture, which can compromise the results and the equipment of measurement of the thermoluminescence of crystals. The change was made at a sampling point and the results were compared with the historical data in the last 30 years. (author)

  13. Studying the cumulative environmental effects of Hydro-Quebec's installations plan

    International Nuclear Information System (INIS)

    Dubeau, D.

    1992-01-01

    The study of the cumulative environmental effects that have been integrated with technical and economic analyses include mercury, land use in the region (territory), natural landscapes, cultural heritages, forest dynamics, regional economies and ways of life. Requests and petitions from the public about Hydro-Quebec projects fall into four categories: welfare of communities, impact on the land, environmental responsibility and preservation of plant and animal species. The cooperation of all concerned is necessary for Hydro-Quebec's developments. (author)

  14. Cumulative (DisAdvantage and the Matthew Effect in Life-Course Analysis.

    Directory of Open Access Journals (Sweden)

    Miia Bask

    Full Text Available To foster a deeper understanding of the mechanisms behind inequality in society, it is crucial to work with well-defined concepts associated with such mechanisms. The aim of this paper is to define cumulative (disadvantage and the Matthew effect. We argue that cumulative (disadvantage is an intra-individual micro-level phenomenon, that the Matthew effect is an inter-individual macro-level phenomenon and that an appropriate measure of the Matthew effect focuses on the mechanism or dynamic process that generates inequality. The Matthew mechanism is, therefore, a better name for the phenomenon, where we provide a novel measure of the mechanism, including a proof-of-principle analysis using disposable personal income data. Finally, because socio-economic theory should be able to explain cumulative (disadvantage and the Matthew mechanism when they are detected in data, we discuss the types of models that may explain the phenomena. We argue that interactions-based models in the literature traditions of analytical sociology and statistical mechanics serve this purpose.

  15. Cumulative health risk assessment: integrated approaches for multiple contaminants, exposures, and effects

    International Nuclear Information System (INIS)

    Rice, Glenn; Teuschler, Linda; MacDonel, Margaret; Butler, Jim; Finster, Molly; Hertzberg, Rick; Harou, Lynne

    2007-01-01

    Available in abstract form only. Full text of publication follows: As information about environmental contamination has increased in recent years, so has public interest in the combined effects of multiple contaminants. This interest has been highlighted by recent tragedies such as the World Trade Center disaster and hurricane Katrina. In fact, assessing multiple contaminants, exposures, and effects has long been an issue for contaminated sites, including U.S. Department of Energy (DOE) legacy waste sites. Local citizens have explicitly asked the federal government to account for cumulative risks, with contaminants moving offsite via groundwater flow, surface runoff, and air dispersal being a common emphasis. Multiple exposures range from ingestion and inhalation to dermal absorption and external gamma irradiation. Three types of concerns can lead to cumulative assessments: (1) specific sources or releases - e.g., industrial facilities or accidental discharges; (2) contaminant levels - in environmental media or human tissues; and (3) elevated rates of disease - e.g., asthma or cancer. The specific initiator frames the assessment strategy, including a determination of appropriate models to be used. Approaches are being developed to better integrate a variety of data, extending from environmental to internal co-location of contaminants and combined effects, to support more practical assessments of cumulative health risks. (authors)

  16. Radiation effects on polyaniline

    International Nuclear Information System (INIS)

    Oki, Yuichi; Kondo, Kenjiro; Suzuki, Takenori; Numajiri, Masaharu; Miura, Taichi; Doi, Shuji; Ohnishi, Toshihiro.

    1992-01-01

    Effects of γ-irradiation on electrical conductivity of polyaniline were investigated. A drastic increase of the conductivity due to radiation-induced doping was observed in combined systems of polyaniline films and halogen-containing polymers. This effect can be applied to measure an integrated radiation dose. (author)

  17. Radiation effects in space

    International Nuclear Information System (INIS)

    Fry, R.J.M.

    1987-07-01

    As more people spend more time in space, and the return to the moon and exploratory missions are considered, the risks require continuing examination. The effects of microgravity and radiation are two potential risks in space. These risks increase with increasing mission duration. This document considers the risk of radiation effects in space workers and explorers. 17 refs., 1 fig., 4 tabs

  18. The effect of ilmenite viscosity on the dynamics and evolution of an overturned lunar cumulate mantle

    Science.gov (United States)

    Zhang, Nan; Dygert, Nick; Liang, Yan; Parmentier, E. M.

    2017-07-01

    Lunar cumulate mantle overturn and the subsequent upwelling of overturned mantle cumulates provide a potential framework for understanding the first-order thermochemical evolution of the Moon. Upwelling of ilmenite-bearing cumulates (IBCs) after the overturn has a dominant influence on the dynamics and long-term thermal evolution of the lunar mantle. An important parameter determining the stability and convective behavior of the IBC is its viscosity, which was recently constrained through rock deformation experiments. To examine the effect of IBC viscosity on the upwelling of overturned lunar cumulate mantle, here we conduct three-dimensional mantle convection models with an evolving core superposed by an IBC-rich layer, which resulted from mantle overturn after magma ocean solidification. Our modeling shows that a reduction of mantle viscosity by 1 order of magnitude, due to the presence of ilmenite, can dramatically change convective planform and long-term lunar mantle evolution. Our model results suggest a relatively stable partially molten IBC layer that has surrounded the lunar core to the present day.Plain Language SummaryThe Moon's mantle is locally ilmenite rich. Previous models exploring the convective evolution of the lunar mantle did not consider the effects of ilmenite viscosity. Recent rock deformation experiments demonstrate that Fe-Ti oxide (ilmenite) is a low viscosity phase compared to olivine and other silicate minerals. Our modeling shows that ilmenite changes the lunar mantle plume process. An ilmenite-rich layer around the lunar core would be highly stable throughout geologic time, consistent with a partially molten, low viscosity layer around the core inferred from seismic attenuation and tidal dissipation.

  19. Radiation effects and radioprotectors

    Energy Technology Data Exchange (ETDEWEB)

    Purohit, R.K., E-mail: dr_rajendra_purohit@yahoo.co.in [Radiation Biology Laboratory, Department of Zoology, Govt. Dungar College, Bikaner (India); Bugalia, Saroj [Department of Zoology, S.K. Kalyan College, Sikar (India); Dakshene, Monika [Department of Chemistry, Govt. College, Kota (India)

    2012-07-01

    Radiation exposure causes damage to biological systems and these damages are mediated by the generation of free radicals and reactive oxygen species targeting vital cellular components such as DNA and membranes. DNA repair systems and the endogenous cellular biochemical defense mechanisms against reactive oxygen species and antioxidants enzymes like reduced Glutathione (GSH), Superoxide dismutase, Glutathione peroxidase catalase etc. fail upon exposures to higher as well as chronic radiation doses leading to alterations in cell functions, cell death or mutations. Radioprotectors prevent these alterations and protect cells and tissues from the deleterious effects of radiations. Radioprotectors are of great importance due to their possible and potential application during planned radiation exposures such as radiotherapy, diagnostic scanning, clean up operations in nuclear accidents, space expeditions etc. and Unplanned radiations exposures such as accidents in nuclear industry, nuclear terrorism, natural background radiation etc. Many of the available synthetic radioprotectors are toxic to mammalian system at doses required to be effective as radioprotector. Increasing uses of ionizing radiation have drawn the attention of many radiobiologists towards their undesired side effects produced in various tissues and for modifying them to facilitate the beneficial uses of radiation. Modification of radiation response is obtained by means of chemical substances that can significantly decrease the magnitude of response when present in a biological system during irradiation. Radioprotectors are chemicals that modify a cell's response to radiation. Radioprotectors are drugs that protect normal (non cancerous) cells from the damage caused by radiation therapy. These agents promote the repair of normal cells that are exposed to radiation. Various chemicals, like Cysteamine, MPG , WR-2721 have been tested for the protection against harmful effects of radiation. These radio

  20. Radiation effects and radioprotectors

    International Nuclear Information System (INIS)

    Purohit, R.K.; Bugalia, Saroj; Dakshene, Monika

    2012-01-01

    Radiation exposure causes damage to biological systems and these damages are mediated by the generation of free radicals and reactive oxygen species targeting vital cellular components such as DNA and membranes. DNA repair systems and the endogenous cellular biochemical defense mechanisms against reactive oxygen species and antioxidants enzymes like reduced Glutathione (GSH), Superoxide dismutase, Glutathione peroxidase catalase etc. fail upon exposures to higher as well as chronic radiation doses leading to alterations in cell functions, cell death or mutations. Radioprotectors prevent these alterations and protect cells and tissues from the deleterious effects of radiations. Radioprotectors are of great importance due to their possible and potential application during planned radiation exposures such as radiotherapy, diagnostic scanning, clean up operations in nuclear accidents, space expeditions etc. and Unplanned radiations exposures such as accidents in nuclear industry, nuclear terrorism, natural background radiation etc. Many of the available synthetic radioprotectors are toxic to mammalian system at doses required to be effective as radioprotector. Increasing uses of ionizing radiation have drawn the attention of many radiobiologists towards their undesired side effects produced in various tissues and for modifying them to facilitate the beneficial uses of radiation. Modification of radiation response is obtained by means of chemical substances that can significantly decrease the magnitude of response when present in a biological system during irradiation. Radioprotectors are chemicals that modify a cell's response to radiation. Radioprotectors are drugs that protect normal (non cancerous) cells from the damage caused by radiation therapy. These agents promote the repair of normal cells that are exposed to radiation. Various chemicals, like Cysteamine, MPG , WR-2721 have been tested for the protection against harmful effects of radiation. These radio

  1. Age- and gender-specific estimates of cumulative CT dose over 5 years using real radiation dose tracking data in children

    International Nuclear Information System (INIS)

    Lee, Eunsol; Goo, Hyun Woo; Lee, Jae-Yeong

    2015-01-01

    It is necessary to develop a mechanism to estimate and analyze cumulative radiation risks from multiple CT exams in various clinical scenarios in children. To identify major contributors to high cumulative CT dose estimates using actual dose-length product values collected for 5 years in children. Between August 2006 and July 2011 we reviewed 26,937 CT exams in 13,803 children. Among them, we included 931 children (median age 3.5 years, age range 0 days-15 years; M:F = 533:398) who had 5,339 CT exams. Each child underwent at least three CT scans and had accessible radiation dose reports. Dose-length product values were automatically extracted from DICOM files and we used recently updated conversion factors for age, gender, anatomical region and tube voltage to estimate CT radiation dose. We tracked the calculated CT dose estimates to obtain a 5-year cumulative value for each child. The study population was divided into three groups according to the cumulative CT dose estimates: high, ≥30 mSv; moderate, 10-30 mSv; and low, <10 mSv. We reviewed clinical data and CT protocols to identify major contributors to high and moderate cumulative CT dose estimates. Median cumulative CT dose estimate was 5.4 mSv (range 0.5-71.1 mSv), and median number of CT scans was 4 (range 3-36). High cumulative CT dose estimates were most common in children with malignant tumors (57.9%, 11/19). High frequency of CT scans was attributed to high cumulative CT dose estimates in children with ventriculoperitoneal shunt (35 in 1 child) and malignant tumors (range 18-49). Moreover, high-dose CT protocols, such as multiphase abdomen CT (median 4.7 mSv) contributed to high cumulative CT dose estimates even in children with a low number of CT scans. Disease group, number of CT scans, and high-dose CT protocols are major contributors to higher cumulative CT dose estimates in children. (orig.)

  2. Man and radiation effects

    International Nuclear Information System (INIS)

    Rausch, L.

    1982-01-01

    The book describes the effects of ionizing radiation on man in a simple, popular, detailed and generally valid manner and gives a comprehensive picture of the concepts, elements, principles of function, and perspectives of medical radiobiology. Radiobiology in general is explained, and its application in research on the causes of radiolesions and radiation diseases as well as a radiotherapy and radiation protection is discussed in popular form. (orig./MG) [de

  3. Biological radiation effects

    International Nuclear Information System (INIS)

    Kiefer, J.

    1989-01-01

    The book covers all aspects of biological radiation effects. The physical basis is dealt with in some detail, and the effects at the subcellular and the cellular level are discussed, taking into account modern developments and techniques. The effects on the human organism are reviewed, both from the point of view of applications in medicine as well as with regard to radiation hazards (teratogenic, gonadal and carcinogenic effects)

  4. A broad-spectrum sunscreen prevents cumulative damage from repeated exposure to sub-erythemal solar ultraviolet radiation representative of temperate latitudes.

    Science.gov (United States)

    Seité, S; Christiaens, F; Bredoux, C; Compan, D; Zucchi, H; Lombard, D; Fourtanier, A; Young, A R

    2010-02-01

    We have previously shown the detrimental effects of 19 sub-erythemal exposures to daily ultraviolet radiation (DUVR, which mimics non-extreme exposure conditions), delivered over 4 weeks to volunteers. This source had UVA (320-400 nm) to UVB (290-320 nm) irradiance ratio of 25, instead of that close to 10 that is typically the case with solar-simulated radiation (SSR) that represents summer global sunlight with a clear sky and quasi-zenith solar irradiance. Here, we report on an extension of this previous study, in which we evaluated the photoprotection afforded by a broad-spectrum daily-care product with a low-sun protection factor (SPF 8, UVA-PF 7 and 3* rated UVA protection). We assessed cellular and molecular markers of photodamage that are relevant to skin cancer and photoageing. This study shows that biological effects of repeated exposure to DUVR can be prevented by a broad-spectrum daily-care product and that the level of protection afforded varies with the studied endpoint. Efficient daily UVR protection, as provided by a broad-spectrum daily-care product, is necessary to prevent the 'silent' sub-erythemal cumulative effects of UVR from inadvertent sun exposure.

  5. Cumulative effects in strategic environmental assessment: The influence of plan boundaries

    Energy Technology Data Exchange (ETDEWEB)

    Bidstrup, Morten, E-mail: bidstrup@plan.aau.dk [Aalborg University (Denmark); Kørnøv, Lone, E-mail: lonek@plan.aau.dk [Aalborg University (Denmark); Partidário, Maria Rosário, E-mail: mariapartidario@tecnico.ulisboa.pt [CEG-IST, Instituto Superior Técnico, Universidade de Lisboa (Portugal)

    2016-02-15

    Cumulative effects (CE) assessment is lacking quality in impact assessment (IA) worldwide. It has been argued that the strategic environmental assessment (SEA) provides a suitable IA framework for addressing CE because it is applied to developments with broad boundaries, but few have tested this claim. Through a case study on the Danish mining sector, this article explores how plan boundaries influence the analytical boundaries applied for assessing CE in SEA. The case was studied through document analysis in combination with semi-structured group interviews of the responsible planners, who also serve as SEA practitioners. It was found that CE are to some extent assessed and managed implicitly throughout the planning process. However, this is through a focus on lowering the cumulative stress of mining rather than the cumulative stress on and capacity of the receiving environment. Plan boundaries do influence CE assessment, though all boundaries are not equally influential. The geographical and time boundaries of the Danish mining plans are broad or flexible enough to accommodate a meaningful assessment of CE, but the topical boundary is restrictive. The study indicates that collaboration among planning authorities and legally appointed CE leadership may facilitate better practice on CE assessment in sector-specific SEA contexts. However, most pressing is the need for relating assessment to the receiving environment as opposed to solely the stress of a proposed plan.

  6. Cumulative effects in strategic environmental assessment: The influence of plan boundaries

    International Nuclear Information System (INIS)

    Bidstrup, Morten; Kørnøv, Lone; Partidário, Maria Rosário

    2016-01-01

    Cumulative effects (CE) assessment is lacking quality in impact assessment (IA) worldwide. It has been argued that the strategic environmental assessment (SEA) provides a suitable IA framework for addressing CE because it is applied to developments with broad boundaries, but few have tested this claim. Through a case study on the Danish mining sector, this article explores how plan boundaries influence the analytical boundaries applied for assessing CE in SEA. The case was studied through document analysis in combination with semi-structured group interviews of the responsible planners, who also serve as SEA practitioners. It was found that CE are to some extent assessed and managed implicitly throughout the planning process. However, this is through a focus on lowering the cumulative stress of mining rather than the cumulative stress on and capacity of the receiving environment. Plan boundaries do influence CE assessment, though all boundaries are not equally influential. The geographical and time boundaries of the Danish mining plans are broad or flexible enough to accommodate a meaningful assessment of CE, but the topical boundary is restrictive. The study indicates that collaboration among planning authorities and legally appointed CE leadership may facilitate better practice on CE assessment in sector-specific SEA contexts. However, most pressing is the need for relating assessment to the receiving environment as opposed to solely the stress of a proposed plan.

  7. Biophysical radiation effects

    International Nuclear Information System (INIS)

    Fidorra, J.

    1982-07-01

    The biological effectiveness of ionizing radiation is based upon the absorption of energy in molecular structures of a cell. Because of the quantum nature of radiation large fluctuations of energy concentration in subcellulare regions has to be considered. In addition both the spatial distribution of a sensitive molecular target and cellulare repair processes has to be taken into consideration for an assessment of radiation action. In radiation protection the difference between the quality factor and the Relative Biological Effectiveness has a fundamental meaning and will be discussed in more detail. The present report includes a short review on some relevant models on radiation action and a short discussion on effects of low dose irradiation. (orig.) [de

  8. Use of significance thresholds to integrate cumulative effects into project-level socio-economic impact assessment in Canada

    International Nuclear Information System (INIS)

    Joseph, Chris; Zeeg, Taylor; Angus, David; Usborne, Anna; Mutrie, Erin

    2017-01-01

    A longstanding critique of project-level environmental assessment is that it is weak at addressing cumulative effects, and because of this many argue that cumulative effects are best managed at a regional scale. However, in the absence of regional management it is important that project-level assessment supports cumulative effects management as best as possible. In this paper we present case study socio-economic impact assessments of liquefied natural gas development on Aboriginal groups on Canada's west coast. The case studies use an analytical structure modified from typical Canadian practice including unambiguous and non-arbitrary significance thresholds grounded in stakeholder values to focus baselines, impact assessment, and significance determination on cumulative effects. This approach is found to be more capable of informing decision-makers on cumulative effects as well as more rigorous and transparent than typical assessments. Much of this approach is not conceptually new, but at least in western Canada such an approach is not typically used or meaningfully implemented by practitioners. As such, the case studies serve to illustrate how practice can bolster project-level assessment. - Highlights: •Typical project assessment is weak with respect to cumulative effects. •Modified analysis structure and thresholds enable a focus on cumulative effects. •Clear, value-based thresholds make analysis rigorous, transparent, and democratic.

  9. Radiation effects in gases

    International Nuclear Information System (INIS)

    Leonhardt, J.W.

    1985-01-01

    Problems in the studies of radiation effects in gases are discussed. By means of ionization- excitation- and electron-capture yields various applications are characterized: ionization detectors, X-ray detectors, radionuclide battery, and radiation-induced chemical gas-phase reactions. Some new results of basic research in respect to the SO 2 oxidation are discussed. (author)

  10. Effects of ionizing radiations

    International Nuclear Information System (INIS)

    Gaussens, G.

    1984-08-01

    After recalling radiation-matter interaction, influence on radiation effects of chemical composition, structure, irradiation atmosphere, dose rate, temperature of organic materials and evolution of electrical, mechanical and physical properties are reviewed. Then behaviour under irradiation of main organic materials: elastomers, thermoplastics, thermosetting plastics, oils and paints are examined. 68 refs [fr

  11. Measurement of radiocesium concentration in trees using cumulative gamma radiation dose rate detection systems - A simple presumption for radiocesium concentration in living woods using glass-badge based gamma radiation dose rate detection system

    Energy Technology Data Exchange (ETDEWEB)

    Yoshihara, T.; Hashida, S.N. [Plant Molecular Biology, Laboratory of Environmental Science, Central Research Institute of Electric Power Industry (CRIEPI), 1646 Abiko, Chiba 270-1194 (Japan); Kawachi, N.; Suzui, N.; Yin, Y.G.; Fujimaki, S. [Radiotracer Imaging Gr., Quantum Beam Science Center, Japan Atomic Energy Agency (JAEA), 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan); Nagao, Y.; Yamaguchi, M. [Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency (JAEA), 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan)

    2014-07-01

    Radiocesium from the severe accident at the Fukushima Dai-ichi Nuclear Power Plant on 11 March 2011 contaminates large areas. After this, a doubt for forest products, especially of mushroom, is indelible at the areas. Pruned woody parts and litters are containing a considerable amount of radiocesium, and generates a problem at incineration and composting. These mean that more attentive survey for each subject is expected; however, the present survey system is highly laborious/expensive and/or non-effective for this purpose. On the other hand, we can see a glass-badge based gamma radiation dose rate detection system. This system always utilized to detect a personal cumulative radiation dose, and thus, it is not suitable to separate a radiation from a specific object. However, if we can separate a radiation from a specific object and relate it with the own radiocesium concentration, it would enable us to presume the specific concentration with just an easy monitoring but without a destruction of the target nature and a complicated process including sampling, pre-treatment, and detection. Here, we present the concept of the measurement and results of the trials. First, we set glass-badges (type FS, Chiyoda Technol Corp., Japan) on a part of bough (approximately 10 cm in diameter) of Japanese flowering cherry trees (Prunus x yedoensis cv. Somei-Yoshino) with four different settings: A, a direct setting without any shield; B, a setting with an aluminum shield between bough and the glass-badge; C, a setting with a lead shield between bough and the glass-badge; D, a setting with a lead shield covering the glass-badge to shut the radiation from the surrounding but from bough. The deduction between the amount of each setting should separate a specific radiation of the bough from unlimited radiation from the surrounding. Even if the hourly dose rate is not enough to count the difference, a moderate cumulative dose would clear the difference. In fact, results demonstrated a

  12. Stagewise pseudo-value regression for time-varying effects on the cumulative incidence

    DEFF Research Database (Denmark)

    Zöller, Daniela; Schmidtmann, Irene; Weinmann, Arndt

    2016-01-01

    In a competing risks setting, the cumulative incidence of an event of interest describes the absolute risk for this event as a function of time. For regression analysis, one can either choose to model all competing events by separate cause-specific hazard models or directly model the association...... for time-varying effects. This is implemented by coupling variable selection between the grid times, but determining estimates separately. The effect estimates are regularized to also allow for model fitting with a low to moderate number of observations. This technique is illustrated in an application...

  13. Electromagnetic and radiation environments: effects on pacemakers

    International Nuclear Information System (INIS)

    Mouton, J.; Trochet, R.; Vicrey, J.; Sauvage, M.; Chauvenet, B.; Ostrovski, A.; Leroy, E.; Haug, R.; Dodinot, B.; Joffre, F.

    1999-01-01

    Nowadays, medical care development allows many people to share the benefits of implanted pacemakers (PM). PM can be perturbed and even fall in complete breakdowns in an electromagnetic and radiation environment. A stimuli-dependent patient can thus be seriously in danger. This article presents the effect of ionizing radiation from either a cobalt-60 source or from a linear accelerator (Saturne 43) on 12 pacemakers. It seems that technological progress make electronic circuits more sensitive to the cumulated dose of radiation. This survey shows that pacemakers have great difficulties to sustain ionizing radiation doses that are commonly delivered to patients during therapies. Usually perturbed functioning appears suddenly and means a strong shift of stimuli that might lead to heart failure

  14. Mismatch or cumulative stress : Toward an integrated hypothesis of programming effects

    NARCIS (Netherlands)

    Nederhof, Esther; Schmidt, Mathias V.

    2012-01-01

    This paper integrates the cumulative stress hypothesis with the mismatch hypothesis, taking into account individual differences in sensitivity to programming. According to the cumulative stress hypothesis, individuals are more likely to suffer from disease as adversity accumulates. According to the

  15. Ionizing radiation, radiation sources, radiation exposure, radiation effects. Pt. 2

    International Nuclear Information System (INIS)

    Schultz, E.

    1985-01-01

    Part 2 deals with radiation exposure due to artificial radiation sources. The article describes X-ray diagnosis complete with an analysis of major methods, nuclear-medical diagnosis, percutaneous radiation therapy, isotope therapy, radiation from industrial generation of nucler energy and other sources of ionizing radiation. In conclusion, the authors attempt to asses total dose, genetically significant dose and various hazards of total radiation exposure by means of a summation of all radiation impacts. (orig./WU) [de

  16. Several problems of cumulative effective mass fraction in anti-seismic analysis

    International Nuclear Information System (INIS)

    Wang Wei; Sheng Feng; Li Hailong; Wen Jing; Luan Lin

    2005-01-01

    Cumulative Effective Mass Fraction (CEMF) is one of important items which sign the accuracy in antiseismic analysis. Based on the primary theories of CEMF, the paper show the influence of CEMF on the accuracy in antiseismic analysis. Moreover, some advices and ways are given to solve common problems in antiseismic analysis, such as how to increase CEMF, how to avoid the mass's loss because of the torsional frequency's being close to the frequency corresponding to the peak of seismic response spectrum, how to avoid the mass's loss because of the constraints, and so on. (authors)

  17. Framework tool for a rapid cumulative effects assessment: case of a prominent wetland in Myanmar.

    Science.gov (United States)

    Pradhan, N; Habib, H; Venkatappa, M; Ebbers, T; Duboz, R; Shipin, O

    2015-06-01

    The wetland of focus, Inle Lake, located in central Myanmar, is well known for its unique biodiversity and culture, as well as for ingenious floating garden agriculture. During the last decades, the lake area has seen extensive degradation in terms of water quality, erosion, deforestation, and biodiversity concomitant with a major shift to unsustainable land use. The study was conducted, with an emphasis on water quality, to analyze environmental impacts (effects) changing the ecosystem and to comprehensively evaluate the environmental state of the ecosystem through an innovative Rapid Cumulative Effects Assessment framework tool. The assessment started with a framework-forming Participatory Rural Appraisal (PRA), which quantified and prioritized impacts over space and time. Critically important impacts were assessed for "intra-inter interactions" using the loop analysis simulation. Water samples were analyzed while geographic information system (GIS) and remote sensing were used to identify water pollution hotspots. It was concluded that out of a plethora of impacts, pollution from municipal sources, sedimentation, and effects exerted by floating gardens had the most detrimental impacts, which cumulatively affected the entire ecosystem. The framework tool was designed in a broad sense with a reference to highly needed assessments of poorly studied wetlands where degradation is evident, but scarcely quantified, and where long-term field studies are fraught with security issues and resource unavailability (post-conflict, poor and remote regions, e.g., Afghanistan, Laos, Sudan, etc.).

  18. The effects of job and family conditions on cumulative fatigue of working mothers in double income family.

    OpenAIRE

    Hirono Ishikawa

    2000-01-01

    The purpose of this study is to investigate the factors in the workplace and in the home which may have effects on cumulative fatigue, and to examine the moderating effect of the quality of family life on the relationship between job related stress and cumulative fatigue. The subject is the sample of working mothers with young children in double income family. Two hypotheses were examined in this study. First, higher level of job related stress and family related stress are both associated ...

  19. Radiation. Doses, effect, risk

    International Nuclear Information System (INIS)

    Vapirev, E.; Todorov, P.

    1994-12-01

    This book outlines in a popular form the topic of ionizing radiation impacts on living organisms. It contains data gathered by ICRP for a period of 35 years. The essential dosimetry terms and units are presented. Natural and artificial sources of ionizing radiation are described. Possible biological radiation effects and diseases as a consequence of external and internal irradiation at normal and accidental conditions are considered. An assessment of genetic risk for human populations is presented and the concept of 'acceptable risk' is discussed

  20. Order effect of strain applications in low-cycle cumulative fatigue at high temperatures

    International Nuclear Information System (INIS)

    Bui-Quoc, T.; Biron, A.

    1977-01-01

    Recent test results on cumulative damage with two strain levels on a stainless steel (AISI 304) at room temperature, 537 and 650 0 C show that the sum of cycle-ratios can be significantly smaller than unity for decreasing levels; the opposite has been noted for increasing levels. As a consequence, the use of the linear damage rule (Miner's law) for life predictions is not conservative in many cases. Since the double linear damage rule (DLDR), originally developed by Manson et al. for room temperature applications, takes the order effect of cyclic loading into consideration, an extension of this rule for high temperature cases may be a potentially useful tool. The present paper is concerned with such an extension. For cumulative damage tests with several levels, according to the DLDR, the summation is applied separately for crack initiation and crack propagation stages, and failure is then assumed to occur when the sum is equal to unity for both stages. Application of the DLDR consists in determining the crack propagation stage Nsub(p) associated with a particular number of cycles at failure N, i.e. Nsub(p)=PNsup(a) where exponent a and coefficient P had been assumed to be equal to 0.6 and 14 respectively for several materials at room temperature. When the DLDR is applied (with a=0.6 and P=14) to predict the remaining life at the second strain level (for two-level cumulative damage) for 304 stainless steel at room temperature 537 0 C and 650 0 C, the results show that the damage due to the first strain level is over-emphasized for decreasing levels when the damaging cycle-ratio is small. For increasing levels, the damage is underestimated and in some testing conditions this damage is simply ignored

  1. Volunteering and health benefits in general adults: cumulative effects and forms.

    Science.gov (United States)

    Yeung, Jerf W K; Zhang, Zhuoni; Kim, Tae Yeun

    2017-07-11

    Although the health benefits of volunteering have been well documented, no research has examined its cumulative effects according to other-oriented and self-oriented volunteering on multiple health outcomes in the general adult public. This study examined other-oriented and self-oriented volunteering in cumulative contribution to health outcomes (mental and physical health, life satisfaction, social well-being and depression). Data were drawn from the Survey of Texas Adults 2004, which contains a statewide population-based sample of adults (n = 1504). Multivariate linear regression and Wald test of parameters equivalence constraint were used to test the relationships. Both forms of volunteering were significantly related to better health outcomes (odds ratios = 3.66% to 11.11%), except the effect of self-oriented volunteering on depression. Other-oriented volunteering was found to have better health benefits than did self-volunteering. Volunteering should be promoted by public health, education and policy practitioners as a kind of healthy lifestyle, especially for the social subgroups of elders, ethnic minorities, those with little education, single people, and unemployed people, who generally have poorer health and less participation in volunteering.

  2. Estimating the Cumulative Ecological Effect of Local Scale Landscape Changes in South Florida

    Science.gov (United States)

    Hogan, Dianna M.; Labiosa, William; Pearlstine, Leonard; Hallac, David; Strong, David; Hearn, Paul; Bernknopf, Richard

    2012-01-01

    Ecosystem restoration in south Florida is a state and national priority centered on the Everglades wetlands. However, urban development pressures affect the restoration potential and remaining habitat functions of the natural undeveloped areas. Land use (LU) planning often focuses at the local level, but a better understanding of the cumulative effects of small projects at the landscape level is needed to support ecosystem restoration and preservation. The South Florida Ecosystem Portfolio Model (SFL EPM) is a regional LU planning tool developed to help stakeholders visualize LU scenario evaluation and improve communication about regional effects of LU decisions. One component of the SFL EPM is ecological value (EV), which is evaluated through modeled ecological criteria related to ecosystem services using metrics for (1) biodiversity potential, (2) threatened and endangered species, (3) rare and unique habitats, (4) landscape pattern and fragmentation, (5) water quality buffer potential, and (6) ecological restoration potential. In this article, we demonstrate the calculation of EV using two case studies: (1) assessing altered EV in the Biscayne Gateway area by comparing 2004 LU to potential LU in 2025 and 2050, and (2) the cumulative impact of adding limestone mines south of Miami. Our analyses spatially convey changing regional EV resulting from conversion of local natural and agricultural areas to urban, industrial, or extractive use. Different simulated local LU scenarios may result in different alterations in calculated regional EV. These case studies demonstrate methods that may facilitate evaluation of potential future LU patterns and incorporate EV into decision making.

  3. Cumulative effects, creeping enclosure, and the marine commons of New Jersey

    Directory of Open Access Journals (Sweden)

    Grant Murray

    2010-02-01

    Full Text Available In response to declining fish stocks and increased societal concern, the marine ‘commons’ of New Jersey is no longer freely available to commercial and recreational fisheries. We discuss the concept of ‘creeping’ enclosure in relation to New Jersey’s marine fisheries and suggest that reduced access can be a cumulative process and function of multiple events and processes and need not be the result of a single regulatory moment. We begin with a short review of the ‘expected’ effects of enclosure, including loss of flexibility, erosion of community, proletarianization of fishermen, and corporatization of the fishery. We then present some findings of our research and discuss how the signs of enclosure are visible in fisheries that do not feature explicitly privatized property or access rights. We rely on an oral history approach and the rich detail that emerges from attention to the lived experiences of fish harvesters to provide a framework for understanding the range of cumulative effects that have resulted from this process of creeping enclosure. We conclude with a discussion of how the gradual process of enclosure has affected the flows of information between the bio-physical environment and fish harvesters, managers and scientists by reducing both participation in fisheries and the accumulation of knowledge itself.

  4. The cumulative effect of consecutive winters' snow depth on moose and deer populations: a defence

    Science.gov (United States)

    McRoberts, R.E.; Mech, L.D.; Peterson, R.O.

    1995-01-01

    1. L. D. Mech et al. presented evidence that moose Alces alces and deer Odocoileus virginianus population parameters re influenced by a cumulative effect of three winters' snow depth. They postulated that snow depth affects adult ungulates cumulatively from winter to winter and results in measurable offspring effects after the third winter. 2. F. Messier challenged those findings and claimed that the population parameters studied were instead affected by ungulate density and wolf indexes. 3. This paper refutes Messier's claims by demonstrating that his results were an artifact of two methodological errors. The first was that, in his main analyses, Messier used only the first previous winter's snow depth rather than the sum of the previous three winters' snow depth, which was the primary point of Mech et al. Secondly, Messier smoothed the ungulate population data, which removed 22-51% of the variability from the raw data. 4. When we repeated Messier's analyses on the raw data and using the sum of the previous three winter's snow depth, his findings did not hold up.

  5. Cumulative effects of road de-icing salt on amphibian behavior.

    Science.gov (United States)

    Denoël, Mathieu; Bichot, Marion; Ficetola, Gentile Francesco; Delcourt, Johann; Ylieff, Marc; Kestemont, Patrick; Poncin, Pascal

    2010-08-15

    Despite growing evidence of the detrimental effect of chemical substances on organisms, limited research has focused on changes in behavioral patterns, in part due to the difficulties to obtain detailed quantitative data. Recent developments in efficient computer-based video analyses have allowed testing pesticide effects on model species such as the zebrafish. However, these new techniques have not yet been applied to amphibians and directly to conservation issues, i.e., to assess toxicological risks on threatened species. We used video-tracking analyses to test a quantitative effect of an environmental contaminant on the locomotion of amphibian tadpoles (Rana temporaria) by taking into account cumulative effects. Because recent research has demonstrated effects of de-icing salts on survival and community structure, we used sodium chloride in our experimental design (25 replicates, 4 concentrations, 4 times) to test for an effect at the scale of behavior at environmentally relevant concentrations. Analysis of 372 1-h video-tracks (5 samples/s) showed a complex action of salts on behavioral patterns with a dose and cumulative response over time. Although no effects were found on mortality or growth, the highest salt concentrations reduced the speed and movement of tadpoles in comparison with control treatments. The reduced locomotor performance could have detrimental consequences in terms of tadpoles' responses to competition and predation and may be an indicator of the low concentration effect of the contaminant. On one hand, this study demonstrates the usefulness of examining behavior to address conservation issues and understand the complex action of environmental factors and, more particularly, pollutants on organisms. On the other hand, our results highlight the need of new computerized techniques to quantitatively analyze these patterns. (c) 2010 Elsevier B.V. All rights reserved.

  6. Handbook of radiation effects

    International Nuclear Information System (INIS)

    Holmes-Siedle, A.; Adams, L.

    1993-01-01

    This handbook is intended to serve as a tool for designers of equipment and scientific instruments in cases where they are required to ensure the survival of the equipment in radiation environments. High-technology materials, especially semiconductors and optics, tend to degrade on exposure to radiation in many different ways. Intense high-energy radiation environments are found in nuclear reactors and accelerators, machines for radiation therapy, industrial sterilization, and space. Some engineers have to build equipment which will survive a nuclear explosion from a hostile source. Proper handling of a disaster with radioactive materials requires equipment which depends utterly on semiconductor microelectronics and imaging devices. Thus the technology of radiation-tolerant electronics is an instrument for good social spheres as diverse as disaster planning and the exploration of Mars. In order to design equipment for intense environments like those described above, then degradation from high-energy irradiation must be seen as a basic design parameter. The aim of this handbook is to assist the engineer or student in that thought; to make it possible to write intelligent specifications; to offer some understanding of the complex variety of effects which occur when high-technology components encounter high-energy radiation; and to go thoroughly into the balance of choices of how to alleviate the effects and hence achieve the design aims of the project. Separate abstracts were prepared for 15 chapters of this book

  7. Cumulative Effect of Racial Discrimination on the Mental Health of Ethnic Minorities in the United Kingdom.

    Science.gov (United States)

    Wallace, Stephanie; Nazroo, James; Bécares, Laia

    2016-07-01

    To examine the longitudinal association between cumulative exposure to racial discrimination and changes in the mental health of ethnic minority people. We used data from 4 waves (2009-2013) of the UK Household Longitudinal Study, a longitudinal household panel survey of approximately 40 000 households, including an ethnic minority boost sample of approximately 4000 households. Ethnic minority people who reported exposure to racial discrimination at 1 time point had 12-Item Short Form Health Survey (SF-12) mental component scores 1.93 (95% confidence interval [CI] = -3.31, -0.56) points lower than did those who reported no exposure to racial discrimination, whereas those who had been exposed to 2 or more domains of racial discrimination, at 2 different time points, had SF-12 mental component scores 8.26 (95% CI = -13.33, -3.18) points lower than did those who reported no experiences of racial discrimination. Controlling for racial discrimination and other socioeconomic factors reduced ethnic inequalities in mental health. Cumulative exposure to racial discrimination has incremental negative long-term effects on the mental health of ethnic minority people in the United Kingdom. Studies that examine exposure to racial discrimination at 1 point in time may underestimate the contribution of racism to poor health.

  8. Evaluation of cumulative effects of MR imaging on pacemaker systems at 1.5 Tesla.

    Science.gov (United States)

    Naehle, Claas P; Zeijlemaker, Volkert; Thomas, Daniel; Meyer, Carsten; Strach, Katharina; Fimmers, Rolf; Schild, Hans; Sommer, Torsten

    2009-12-01

    The purpose of this study was to evaluate possible cumulative effects of repeated magnetic resonance imaging (MRI) examinations on pacemaker systems in patients with cardiac pacemakers. The records of pacemaker patients who underwent repetitive MRI examinations in our institution were reviewed to identify patients who underwent two or more MRI examinations at 1.5T of any anatomical region. Using these criteria, a total of 47 patients who underwent a total 171 MRI examinations were identified and included in this study. Institutional Review Board approval for all pacemaker investigations was obtained. Written informed consent was obtained from all patients. Pacemakers were interrogated immediately before and after MR imaging, and after 3 months, including measurement of pacing capture threshold (PCT), lead impedance (LI), and battery voltage (BV). PCT, LI, and BV were analyzed for changes dependant on the number of MRI exams performed. Mean changes over time and changes between first and last pacemaker interrogation of PCT, LI, and BV were calculated. A statistically significant (P < 0.05), but clinically irrelevant trend for decrease in PCT and BV was found. No significant or clinically relevant changes in LI were observed. In this first study, no clinically relevant, cumulative changes in PCT, LI, or BV could be detected in PM patients who underwent two or more MRI examinations. However, a careful benefit/risk evaluation, among other MRI- and pacemaker-related safety precautions, remains mandatory, as clinically relevant alterations to the PM system cannot be excluded by all means.

  9. Biological Effects of Radiation

    International Nuclear Information System (INIS)

    Jatau, B.D.; Garba, N.N.; Yusuf, A.M.; Yamusa, Y. A.; Musa, Y.

    2013-01-01

    In earlier studies, researchers aimed a single particle at the nucleus of the cell where DNA is located. Eighty percent of the cells shot through the nucleus survived. This contradicts the belief that if radiation slams through the nucleus, the cell will die. But the bad news is that the surviving cells contained mutations. Cells have a great capacity to repair DNA, but they cannot do it perfectly. The damage left behind in these studies from a single particle of alpha radiation doubled the damage that is already there. This proved, beyond a shadow of doubt, those there biological effects occur as a result of exposure to radiation, Radiation is harmful to living tissue because of its ionizing power in matter. This ionization can damage living cells directly, by breaking the chemical bonds of important biological molecules (particularly DNA), or indirectly, by creating chemical radicals from water molecules in the cells, which can then attack the biological molecules chemically. At some extent these molecules are repaired by natural biological processes, however, the effectiveness of this repair depends on the extent of the damage. The interaction of ionizing with the human body, arising either from external sources outside the body or from internal contamination of the body by radioactive materials, leads to the biological effects which may later show up as a clinical symptoms. Basically, this formed the baseline of this research to serve as a yardstick for creating awareness about radiation and its resulting effects.

  10. Biological Effects of Ionizing Radiation

    Science.gov (United States)

    Ingram, M.; Mason, W. B.; Whipple, G. H.; Howland, J. W.

    1952-04-07

    This report presents a review of present knowledge and concepts of the biological effects of ionizing radiations. Among the topics discussed are the physical and chemical effects of ionizing radiation on biological systems, morphological and physiological changes observed in biological systems subjected to ionizing radiations, physiological changes in the intact animal, latent changes following exposure of biological systems to ionizing radiations, factors influencing the biological response to ionizing radiation, relative effects of various ionizing radiations, and biological dosimetry.

  11. Radiation effects on living systems

    International Nuclear Information System (INIS)

    Hawley, N.J.

    1980-10-01

    This bibliography includes papers and reports by Atomic Energy of Canada Limited scientists concerning radiation effects on living systems. It is divided into three sections: Radiobiology, Radiation Biochemistry and Radiation Chemistry. (auth)

  12. Intermediate Results Of The Program On Realization Of High-Power Soft X-ray Radiation Source Powered From Magneto-Cumulative Generators

    International Nuclear Information System (INIS)

    Selemir, V.D.; Demidov, V.A.; Ermolovich, V.F.; Spirov, G.M.; Repin, P.B.; Pikulin, I.V.; Volkov, A.A.; Orlov, A.P.; Boriskin, A.S.; Tatsenko, O.M.; Markevtsev, I.M.; Moiseenko, A.N.; Kazakov, S.A.; Selyavsky, V.T.; Shapovalov, E.V.; Giterman, B.P.; Vlasov, Yu.V.; Dydykin, P.S.; Ryaslov, E.A.; Kotelnikov, D.V.

    2006-01-01

    In the paper we discuss experiments on wire liner systems powering from helical and disk magneto-cumulative generators with a current from 2...3 MA up to 20 MA at current rise time from 0.3 μs to 1 μs, respectively. At currents level up to 4 MA maximum yield of soft x-ray radiation was more than 100 kJ at plasma pinch temperature of 55 eV. At currents up to 20 MA an expected yield of soft x-ray radiation exceeds 1 MJ

  13. Shale Gas Development and Brook Trout: Scaling Best Management Practices to Anticipate Cumulative Effects

    Science.gov (United States)

    Smith, David; Snyder, Craig D.; Hitt, Nathaniel P.; Young, John A.; Faulkner, Stephen P.

    2012-01-01

    Shale gas development may involve trade-offs between energy development and benefits provided by natural ecosystems. However, current best management practices (BMPs) focus on mitigating localized ecological degradation. We review evidence for cumulative effects of natural gas development on brook trout (Salvelinus fontinalis) and conclude that BMPs should account for potential watershed-scale effects in addition to localized influences. The challenge is to develop BMPs in the face of uncertainty in the predicted response of brook trout to landscape-scale disturbance caused by gas extraction. We propose a decision-analysis approach to formulating BMPs in the specific case of relatively undisturbed watersheds where there is consensus to maintain brook trout populations during gas development. The decision analysis was informed by existing empirical models that describe brook trout occupancy responses to landscape disturbance and set bounds on the uncertainty in the predicted responses to shale gas development. The decision analysis showed that a high efficiency of gas development (e.g., 1 well pad per square mile and 7 acres per pad) was critical to achieving a win-win solution characterized by maintaining brook trout and maximizing extraction of available gas. This finding was invariant to uncertainty in predicted response of brook trout to watershed-level disturbance. However, as the efficiency of gas development decreased, the optimal BMP depended on the predicted response, and there was considerable potential value in discriminating among predictive models through adaptive management or research. The proposed decision-analysis framework provides an opportunity to anticipate the cumulative effects of shale gas development, account for uncertainty, and inform management decisions at the appropriate spatial scales.

  14. Addressing trend-related changes within cumulative effects studies in water resources planning

    Energy Technology Data Exchange (ETDEWEB)

    Canter, L.W., E-mail: envimptr@aol.com [University of Oklahoma, Norman, Oklahoma and President, Canter Associates, Inc., Horseshoe Bay, TX (United States); Chawla, M.K. [ERDC-CERL, U.S. Army Corps of Engineers, Champaign, IL (United States); Swor, C.T. [Canter Associates, Inc., Frankewing, TN (United States)

    2014-01-15

    Summarized herein are 28 case studies wherein trend-related causative physical, social, or institutional changes were connected to consequential changes in runoff, water quality, and riparian and aquatic ecological features. The reviewed cases were systematically evaluated relative to their identified environmental effects; usage of analytical frameworks, and appropriate models, methods, and technologies; and the attention given to mitigation and/or management of the resultant causative and consequential changes. These changes also represent important considerations in project design and operation, and in cumulative effects studies associated therewith. The cases were grouped into five categories: institutional changes associated with legislation and policies (seven cases); physical changes from land use changes in urbanizing watersheds (eight cases); physical changes from land use changes and development projects in watersheds (four cases); physical, institutional, and social changes from land use and related policy changes in river basins (three cases); and multiple changes within a comprehensive study of land use and policy changes in the Willamette River Basin in Oregon (six cases). A tabulation of 110 models, methods and technologies used in the studies is also presented. General observations from this review were that the features were unique for each case; the consequential changes were logically based on the causative changes; the analytical frameworks provided relevant structures for the studies, and the identified methods and technologies were pertinent for addressing both the causative and consequential changes. One key lesson was that the cases provide useful, “real-world” illustrations of the importance of addressing trend-related changes in cumulative effects studies within water resources planning. Accordingly, they could be used as an “initial tool kit” for addressing trend-related changes.

  15. Addressing trend-related changes within cumulative effects studies in water resources planning

    International Nuclear Information System (INIS)

    Canter, L.W.; Chawla, M.K.; Swor, C.T.

    2014-01-01

    Summarized herein are 28 case studies wherein trend-related causative physical, social, or institutional changes were connected to consequential changes in runoff, water quality, and riparian and aquatic ecological features. The reviewed cases were systematically evaluated relative to their identified environmental effects; usage of analytical frameworks, and appropriate models, methods, and technologies; and the attention given to mitigation and/or management of the resultant causative and consequential changes. These changes also represent important considerations in project design and operation, and in cumulative effects studies associated therewith. The cases were grouped into five categories: institutional changes associated with legislation and policies (seven cases); physical changes from land use changes in urbanizing watersheds (eight cases); physical changes from land use changes and development projects in watersheds (four cases); physical, institutional, and social changes from land use and related policy changes in river basins (three cases); and multiple changes within a comprehensive study of land use and policy changes in the Willamette River Basin in Oregon (six cases). A tabulation of 110 models, methods and technologies used in the studies is also presented. General observations from this review were that the features were unique for each case; the consequential changes were logically based on the causative changes; the analytical frameworks provided relevant structures for the studies, and the identified methods and technologies were pertinent for addressing both the causative and consequential changes. One key lesson was that the cases provide useful, “real-world” illustrations of the importance of addressing trend-related changes in cumulative effects studies within water resources planning. Accordingly, they could be used as an “initial tool kit” for addressing trend-related changes

  16. Pediatric cleft palate patients show a 3- to 5-fold increase in cumulative radiation exposure from dental radiology compared with an age- and gender-matched population: a retrospective cohort study.

    Science.gov (United States)

    Jacobs, Reinhilde; Pauwels, Ruben; Scarfe, William C; De Cock, Carl; Dula, Karl; Willems, Guy; Verdonck, An; Politis, Constantinus

    2018-05-01

    The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 μSv at the age of 20 years) than non-CP patients with (597 μSv) and without (383 μSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.

  17. Cumulative effect of structural nonlinearities: chaotic dynamics of cantilever beam system with impacts

    International Nuclear Information System (INIS)

    Emans, Joseph; Wiercigroch, Marian; Krivtsov, Anton M.

    2005-01-01

    The nonlinear analysis of a common beam system was performed, and the method for such, outlined and presented. Nonlinear terms for the governing dynamic equations were extracted and the behaviour of the system was investigated. The analysis was carried out with and without physically realistic parameters, to show the characteristics of the system, and the physically realistic responses. Also, the response as part of a more complex system was considered, in order to investigate the cumulative effects of nonlinearities. Chaos, as well as periodic motion was found readily for the physically unrealistic parameters. In addition, nonlinear behaviour such as co-existence of attractors was found even at modest oscillation levels during investigations with realistic parameters. When considered as part of a more complex system with further nonlinearities, comparisons with linear beam theory show the classical approach to be lacking in accuracy of qualitative predictions, even at weak oscillations

  18. Unique versus cumulative effects of physical and sexual assault on patterns of adolescent substance use

    DEFF Research Database (Denmark)

    Charak, R.; Koot, H. M.; Dvorak, R. D.

    2015-01-01

    The present study assessed the unique versus cumulative effects of physical and sexual assault, on patterns of substance-use in adolescents. It was hypothesized that experiencing a single assault (physical or sexual) when compared with exposure to both physical and sexual assault would be more...... strongly related to membership of polysubstance use classes. From the National Survey of Adolescents-1995 (N=4023) 918 adolescents (age range=12-17 years, M=14.92, 49.6% female) with reports of physical assault and/or sexual assault were selected. Using information on alcohol-use, cigarette...... to a single type of assault those exposed to both physical and sexual assault were two-to-three times more likely to be in the heavier polysubstance-use class. Females were more likely to be members of the polysubstance-use class than of the experimental use class. Gender did not emerge as a significant...

  19. Biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Heribanova, A.

    1995-01-01

    The basic principles and pathways of effects of ionizing radiation on living organisms and cells are outlined. The following topics are covered: effects of radiation on living matter (direct effects, radical or indirect effects, dual radiation action, and molecular biological theories); effects of radiation on cells and tissues (cell depletion, changes in the cytogenetic information, reparation mechanisms), dose-response relationship (deterministic effects, stochastic effects), and the effects of radiation on man (acute radiation sickness, acute local changes, fetus injuries, non-tumorous late injuries, malignant tumors, genetic changes). (P.A.). 3 tabs., 2 figs., 5 refs

  20. Bystander effects of radiation

    International Nuclear Information System (INIS)

    Umar, Neethu Fathima; Daniel, Nittu

    2013-01-01

    The Radiation-Induced Bystander Effect is the phenomenon in which unirradiated cells show irradiated effects due to the signals received from nearby irradiated cells. Evidence suggests that targeted cytoplasmic irradiation results in mutation in the nucleus of the hit cells. Cells that are not directly hit by an alpha particle, but are in the vicinity of one that is hit, also contribute to the genotoxic response of the cell population. When cells are irradiated, and the medium is transferred to unirradiated cells, these unirradiated cells show bystander responses when assayed for clonogenic survival and oncogenic transformation. The demonstration of a bystander effect in human tissues and, more recently, in whole organisms have clear implication of the potential relevance of the non-targeted response to human health. This effect may also contribute to the final biological consequences of exposure to low doses of radiation. The radiation-induced bystander effect represents a paradigm shift in our understanding of the radiobiological effects of ionizing radiation, in that extranuclear and extracellular events may also contribute to the final biological consequences of exposure to low doses of radiation. Multiple pathways are involved in the bystander phenomenon, and different cell types respond differently to bystander signalling. Using cDNA microarrays, a number of cellular signalling genes, including cyclooxygenase-2 (CQX-2), have been shown to be casually linked to the bystander phenomenon. The observation that inhibition of the phosphorylation of extracellular signal-related kinase (ERK) suppressed the bystander response further confirmed the important role of the mitogen-activated protein kinase (MAPK) signalling cascade in the bystander process. The cells deficient in mitochondrial DNA showed a significantly reduced response to bystander signalling, suggesting a functional role of mitochondria in the signalling process. (author)

  1. Radiation effects on superconductivity

    International Nuclear Information System (INIS)

    Brown, B.S.

    1975-01-01

    The effect of radiation on the superconducting transition temperature (T/sub c/), upper critical field (H/sub c2/), and volume-pinning-force density (F/sub p/) were discussed for the three kinds of superconducting material (elements, alloys, and compounds). 11 figures, 3 tables, 86 references

  2. Cumulative Effect of Obesogenic Behaviours on Adiposity in Spanish Children and Adolescents

    Science.gov (United States)

    Schröder, Helmut; Bawaked, Rowaedh Ahmed; Ribas-Barba, Lourdes; Izquierdo-Pulido, Maria; Roman-Viñas, Blanca; Fíto, Montserrat; Serra-Majem, Lluis

    2018-01-01

    Objective Little is known about the cumulative effect of obesogenic behaviours on childhood obesity risk. We determined the cumulative effect on BMI z-score, waist-to-height ratio (WHtR), overweight and abdominal obesity of four lifestyle behaviours that have been linked to obesity. Methods In this cross-sectional analysis, data were obtained from the EnKid sudy, a representative sample of Spanish youth. The study included 1,614 boys and girls aged 5-18 years. Weight, height and waist circumference were measured. Physical activity (PA), screen time, breakfast consumption and meal frequency were self-reported on structured questionnaires. Obesogenic behaviours were defined as 1 SD from the mean of the WHO reference population. Abdominal obesity was defined as a WHtR ≥ 0.5. Results High screen time was the most prominent obesogenic behaviour (49.7%), followed by low physical activity (22.4%), low meal frequency (14.4%), and skipping breakfast (12.5%). Although 33% of participants were free of all 4 obesogenic behaviours, 1, 2, and 3 or 4 behaviours were reported by 44.5%, 19.3%, and 5.0%, respectively. BMI z-score and WHtR were positively associated (p < 0.001) with increasing numbers of concurrent obesogenic behaviours. The odds of presenting with obesogenic behaviours were significantly higher in children who were overweight (OR 2.68; 95% CI 1.50; 4.80) or had abdominal obesity (OR 2.12; 95% CI 1.28; 3.52); they reported more than 2 obesogenic behaviours. High maternal and parental education was inversely associated (p = 0.004 and p < 0.001, respectively) with increasing presence of obesogenic behaviours. Surrogate markers of adiposity increased with numbers of concurrent presence of obesogenic behaviours. The opposite was true for high maternal and paternal education. PMID:29207394

  3. Genetic effects of radiation

    International Nuclear Information System (INIS)

    Selby, P.B.

    1977-01-01

    Many of the most important findings concerning the genetic effects of radiation have been obtained in the Biology Division of Oak Ridge National Laboratory. The paper focuses on some of the major discoveries made in the Biology Division and on a new method of research that assesses damage to the skeletons of mice whose fathers were irradiated. The results discussed have considerable influence upon estimates of genetic risk in humans from radiation, and an attempt is made to put the estimated amount of genetic damage caused by projected nuclear power development into its proper perspective

  4. Application of approximations for joint cumulative k-distributions for mixtures to FSK radiation heat transfer in multi-component high temperature non-LTE plasmas

    International Nuclear Information System (INIS)

    Maurente, André; França, Francis H.R.; Miki, Kenji; Howell, John R.

    2012-01-01

    Approximations for joint cumulative k-distribution for mixtures are efficient for full spectrum k-distribution (FSK) computations. These approximations provide reduction of the database that is necessary to perform FSK computation when compared to the direct approach, which uses cumulative k-distributions computed from the spectrum of the mixture, and also less computational expensive when compared to techniques in which RTE's are required to be solved for each component of the mixture. The aim of the present paper is to extend the approximations for joint cumulative k-distributions for non-LTE media. For doing that, a FSK to non-LTE media formulation well-suited to be applied along with approximations for joint cumulative k-distributions is presented. The application of the proposed methodology is demonstrated by solving the radiation heat transfer in non-LTE high temperature plasmas composed of N, O, N 2 , NO, N 2 + and mixtures of these species. The two more efficient approximations, that is, the superposition and multiplication are employed and analyzed.

  5. The Scarring Effects of Bankruptcy: Cumulative Disadvantage across Credit and Labor Markets

    Science.gov (United States)

    Maroto, Michelle

    2012-01-01

    As the recent economic crisis has demonstrated, inequality often spans credit and labor markets, supporting a system of cumulative disadvantage. Using data from the National Longitudinal Survey of Youth, this research draws on stigma, cumulative disadvantage and status characteristics theories to examine whether credit and labor markets intersect…

  6. Depressive Symptoms in College Women: Examining the Cumulative Effect of Childhood and Adulthood Domestic Violence.

    Science.gov (United States)

    Al-Modallal, Hanan

    2016-10-01

    The purpose of this study was to examine the cumulative effect of childhood and adulthood violence on depressive symptoms in a sample of Jordanian college women. Snowball sampling technique was used to recruit the participants. The participants were heterosexual college-aged women between the ages of 18 and 25. The participants were asked about their experiences of childhood violence (including physical violence, sexual violence, psychological violence, and witnessing parental violence), partner violence (including physical partner violence and sexual partner violence), experiences of depressive symptoms, and about other demographic and familial factors as possible predictors for their complaints of depressive symptoms. Multiple linear regression analysis was implemented to identify demographic- and violence-related predictors of their complainants of depressive symptoms. Logistic regression analysis was further performed to identify possible type(s) of violence associated with the increased risk of depressive symptoms. The prevalence of depressive symptoms in this sample was 47.4%. For the violence experience, witnessing parental violence was the most common during childhood, experienced by 40 (41.2%) women, and physical partner violence was the most common in adulthood, experienced by 35 (36.1%) women. Results of logistic regression analysis indicated that experiencing two types of violence (regardless of the time of occurrence) was significant in predicting depressive symptoms (odds ratio [OR] = 3.45, p < .05). Among college women's demographic characteristics, marital status (single vs. engaged), mothers' level of education, income, and smoking were significant in predicting depressive symptoms. Assessment of physical violence and depressive symptoms including the cumulative impact of longer periods of violence on depressive symptoms is recommended to be explored in future studies. © The Author(s) 2015.

  7. Cumulative and competitive effects of chemical elements on nuclear glass alteration

    International Nuclear Information System (INIS)

    Arena, Helene

    2016-01-01

    This work takes place in the context of the long-term behavior of nuclear glasses under repository conditions. The main objective is to identify, understand and compare the effects of some chemical elements present in the glass composition and/or in the repository media (Zn, Mg, Ni, Co, Fe, Ca, Gd, Ce, K, Cs, Cr and Ag) on the processes involved in glass alteration by water. The cumulative or competitive nature of the effects of these chemical elements was determined. To reach this goal, a 6 oxides simple glass (ISG) has been altered for more than 500 days in a solution containing one or more of the chemical elements of interest. The results indicate that Zn, Mg, Ni, Co and Fe elements increase glass alteration forming secondary phases with the same structure and stoichiometry (tri-octahedral smectites). To form, these silicates consume chemical elements (Si, Al) from the environment and induce a pH decrease until a limiting value of pH. Beyond this pH the precipitation of secondary phases is inhibited and these chemical elements can be integrated into the gel, replacing Ca whose solubility increases at lower pH. As long as they form secondary phases, the effects of these elements are cumulative. Rare earths Gd and Ce also increase glass alteration forming secondary phases but their effects are lower as they contain less silicon. These elements are not integrated in the gel. Chromium increases glass alteration by precipitating with Ca and leading to a less protective gel, depleted in Ca. Silver precipitates as AgCl and has no effect on the alteration of the glass. The chemical elements K, Cs and Ca limit glass alteration by integrating into the gel and slowing down the transport phenomena therein. This integration is competitive: the order of integration (quantity and effectiveness glass alteration limitation) is the following Ca≥≥Cs≥K. Thus, the increase of glass alteration may be proportional to the quantity of elements promoting the precipitation of

  8. On the development of online cities and neighborhoods: an exploration of cumulative and segmentive network effects in social media

    NARCIS (Netherlands)

    Maris, I.; Huizinga, A; Bouman, W.; Tuunainen, V.K.; Rossi, M.; Nandhakumar, J.

    2011-01-01

    This paper outlines a research in progress set to study network effects in social media. The focus is on outlining the theoretical framework in which this study is embedded. The concepts of cumulative network effects and segmentive network effects are introduced to explain the processes by which

  9. Biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Marko, A.M.

    1981-05-01

    In this review radiation produced by the nuclear industry is placed into context with other sources of radiation in our world. Human health effects of radiation, derivation of standards and risk estimates are reviewed in this document. The implications of exposing the worker and the general population to radiation generated by nuclear power are assessed. Effects of radiation are also reviewed. Finally, gaps in our knowledge concerning radiation are identified and current research on biological effects, on environmental aspects, and on dosimetry of radiation within AECL and Canada is documented in this report. (author)

  10. Cumulative effective dose and cancer risk for pediatric population in repetitive full spine follow-up imaging: How micro dose is the EOS microdose protocol?

    Science.gov (United States)

    Law, Martin; Ma, Wang-Kei; Lau, Damian; Cheung, Kenneth; Ip, Janice; Yip, Lawrance; Lam, Wendy

    2018-04-01

    To evaluate and to obtain analytic formulation for the calculation of the effective dose and associated cancer risk using the EOS microdose protocol for scoliotic pediatric patients undergoing full spine imaging at different age of exposure; to demonstrate the microdose protocol capable of delivering lesser radiation dose and hence of further reducing cancer risk induction when compared with the EOS low dose protocol; to obtain cumulative effective dose and cancer risk for both genders scoliotic pediatrics of US and Hong Kong population using the microdose protocol. Organ absorbed doses of full spine exposed scoliotic pediatric patients have been simulated with the use of EOS microdose protocol imaging parameters input to the Monte Carlo software PCXMC. Gender and age specific effective dose has been calculated with the simulated organ absorbed dose using the ICRP-103 approach. The associated radiation induced cancer risk, expressed as lifetime attributable risk (LAR), has been estimated according to the method introduced in the Biological Effects of Ionizing Radiation VII report. Values of LAR have been estimated for scoliotic patients exposed repetitively during their follow up period at different age for US and Hong Kong population. The effective doses of full spine imaging with simultaneous posteroanterior and lateral projection for patients exposed at the age between 5 and 18 years using the EOS microdose protocol have been calculated within the range of 2.54-14.75 μSv. The corresponding LAR for US and Hong Kong population was ranged between 0.04 × 10 -6 and 0.84 × 10 -6 . Cumulative effective dose and cancer risk during follow-up period can be estimated using the results and are of information to patients and their parents. With the use of computer simulation and analytic formulation, we obtained the cumulative effective dose and cancer risk at any age of exposure for pediatric patients of US and Hong Kong population undergoing repetitive

  11. Addressing cumulative effects through strategic environmental assessment: a case study of small hydro development in Newfoundland, Canada

    International Nuclear Information System (INIS)

    Bonnell, S.; Storey, K.

    2000-01-01

    Environmental assessment (EA) is widely used as a means of incorporating environmental considerations into decision-making, primarily at the project level. The scope of EA has been expanded considerably in recent years to include earlier stages of the decision-making process, namely, policies, plans and programmes. Strategic environmental assessment (SEA) facilitates a planning approach to addressing the overall, cumulative effects of the projects that occur as a result of these decisions. This paper demonstrates the potential benefits of SEA in the assessment and management of cumulative effects, using a case study of recent hydroelectric development planning in Newfoundland, Canada. It goes on to illustrate how SEA could be used to address potential cumulative effects at the various stages of such a decision-making process. Through the case study, the paper also explores a number of issues in the implementation of such a planning approach. (author)

  12. Radiation Effects Research Foundation

    International Nuclear Information System (INIS)

    1979-01-01

    The last day of March 1978 marked the completion of the first 3 years of operation of the Radiation Effects Research Foundation in Hiroshima and Nagasaki. RERF was established on 1 April 1975 as successor to the Atomic Bomb Casualty Commission which had been in continuous operation since 1947. This record of the first 3 years of operation consists of selected reports and other documents prepared in the course of conducting the business of RERF and includes a brief history, a late radiation effects that might be conducted at RERF. The wisdom and thought given to the research program and its operation by the Scientific Council and the Board of Directors is reflected in the minutes of their meetings which are included in the Appendix. (Mori, K.)

  13. Modeling the Cumulative Effects of Social Exposures on Health: Moving beyond Disease-Specific Models

    Directory of Open Access Journals (Sweden)

    Heather L. White

    2013-03-01

    Full Text Available The traditional explanatory models used in epidemiology are “disease specific”, identifying risk factors for specific health conditions. Yet social exposures lead to a generalized, cumulative health impact which may not be specific to one illness. Disease-specific models may therefore misestimate social factors’ effects on health. Using data from the Canadian Community Health Survey and Canada 2001 Census we construct and compare “disease-specific” and “generalized health impact” (GHI models to gauge the negative health effects of one social exposure: socioeconomic position (SEP. We use logistic and multinomial multilevel modeling with neighbourhood-level material deprivation, individual-level education and household income to compare and contrast the two approaches. In disease-specific models, the social determinants under study were each associated with the health conditions of interest. However, larger effect sizes were apparent when outcomes were modeled as compound health problems (0, 1, 2, or 3+ conditions using the GHI approach. To more accurately estimate social exposures’ impacts on population health, researchers should consider a GHI framework.

  14. Do self-reported concussions have cumulative or enduring effects on drivers' anticipation of traffic hazards?

    Science.gov (United States)

    Preece, Megan H W; Horswill, Mark S; Ownsworth, Tamara

    2016-01-01

    To investigate the cumulative effect of multiple self-reported concussions and the enduring effect of concussion on drivers' hazard perception ability. It was hypothesized: (1) that individuals reporting multiple previous concussions would be slower to anticipate traffic hazards than individuals reporting either one previous concussion or none; and (2) that individuals reporting a concussion within the past 3 months would be slower to anticipate traffic hazards than individuals reporting either an earlier concussion or no prior concussion. Two hundred and eighty-two predominantly young drivers (nconcussed = 68, Mage = 21.57 years, SDage = 6.99 years, 66% female) completed a validated hazard perception test (HPT) and measures of emotional, cognitive, health and driving status. A one-way analysis of variance showed that there was no significant effect of concussion number on HPT response times. Similarly, pairwise comparisons showed no significant differences between the HPT response times of individuals reporting a concussion within the previous 3 months, individuals reporting an earlier concussion and the never concussed group. The findings suggest that previous concussions do not adversely affect young drivers' ability to anticipate traffic hazards; however, due to reliance on self-reports of concussion history, further prospective longitudinal research is needed.

  15. The cumulative analgesic effect of repeated electroacupuncture involves synaptic remodeling in the hippocampal CA3 region☆

    Science.gov (United States)

    Xu, Qiuling; Liu, Tao; Chen, Shuping; Gao, Yonghui; Wang, Junying; Qiao, Lina; Liu, Junling

    2012-01-01

    In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanli (ST36) and Yanglingquan (GB34) once a day for 14 consecutive days in a rat model of chronic sciatic nerve constriction injury-induced neuropathic pain. In addition, concomitant changes in calcium/calmodulin-dependent protein kinase II expression and synaptic ultrastructure of neurons in the hippocampal CA3 region were examined. The thermal pain threshold (paw withdrawal latency) was increased significantly in both groups at 2 weeks after electroacupuncture intervention compared with 2 days of electroacupuncture. In ovariectomized rats with chronic constriction injury, the analgesic effect was significantly reduced. Electroacupuncture for 2 weeks significantly diminished the injury-induced increase in synaptic cleft width and thinning of the postsynaptic density, and it significantly suppressed the down-regulation of intracellular calcium/calmodulin-dependent protein kinase II expression in the hippocampal CA3 region. Repeated electroacupuncture intervention had a cumulative analgesic effect on injury-induced neuropathic pain reactions, and it led to synaptic remodeling of hippocampal neurons and upregulated calcium/calmodulin-dependent protein kinase II expression in the hippocampal CA3 region. PMID:25657670

  16. Radiation Bystander Effects Mechanism

    Directory of Open Access Journals (Sweden)

    Shokohzaman Soleymanifard

    2009-06-01

    Full Text Available Introduction: Radiation Induced Bystander Effect (RIBE which cause radiation effects in non-irradiated cells, has challenged the principle according to which radiation traversal through the nucleus of a cell is necessary for producing biological responses. What is the mechanism of this phenomenon? To have a better understanding of this rather ambiguous concept substantial number of original and reviewed article were carefully examined. Results: Irradiated cells release molecules which can propagate in cell environment and/or transmit through gap junction intercellular communication. These molecules can reach to non-irradiated cells and transmit bystander signals. In many investigations, it has been confirmed that these molecules are growth factors, cytokines, nitric oxide and free radicals like reactive oxygen species (ROS. Transmission of by stander signal to neighboring cells persuades them to produce secondary growth factors which in their turn cause further cell injuries. Some investigators suggest, organelles other than nucleus (mitochondria and cell membrane are the origin of these signals.  There is another opinion which suggests double strand breaks (DSB are not directly generated in bystander cells, rather they are due to smaller damage like single strand breaks which accumulate and end up to DSB. Although bystander mechanisms have not been exactly known, it can be confirmed that multiple mechanisms and various pathways are responsible for this effect. Cell type, radiation type, experimental conditions and end points identify the dominant mechanism. Conclusion: Molecules and pathways which are responsible for RIBE, also cause systemic responses to other non-irradiation stresses. So RIBE is a kind of systemic stress or innate immune responses, which are performed by cell microenvironment. Irradiated cells and their signals are components of microenvironment for creating bystander effects.

  17. Radiation effects in metals

    International Nuclear Information System (INIS)

    Leteurtre Jean.

    1978-01-01

    The current understanding of radiation damage in metals is reviewed, simplifying the actual complexity of the effects by considering some aspects separately. The production of point defects in metals, the primary damage state are first studied. The second part of the lecture is devoted to the evolution of this primary damage state as a function of temperature and dose: the steady state concentration of point defects, the nucleation of secondary defects and their growth are successively considered

  18. Cumulative childhood trauma and psychological maladjustment of sexually abused children in Korea: mediating effects of emotion regulation.

    Science.gov (United States)

    Choi, Ji Young; Oh, Kyung Ja

    2014-02-01

    The purpose of the present study was to identify the mediating effects of emotion regulation on the association between cumulative childhood trauma and behavior problems in sexually abused children in Korea, using structural equation modeling (SEM). Data were collected on 171 children (ages 6-13 years) referred to a public counseling center for sexual abuse in Seoul, Korea. Cumulative childhood traumas were defined on the basis of number of traumas (physical abuse, witnessing domestic violence, neglect, traumatic separation from parent, and sexual abuse) and the severity and duration of traumas. Children were evaluated by their parents on emotion regulation using the Emotion Regulation Checklist and internalizing and externalizing behavior problems using the Korean-Child Behavior Checklist. SEM analyses confirmed the complete mediation model, in which emotion dysregulation fully mediates the relationship between cumulative childhood traumas and internalizing/externalizing behavior problems. These findings indicate that emotion regulation is an important mechanism that can explain the negative effects of cumulative childhood traumas and that there is a need to focus on emotion regulation in sexually abused children exposed to cumulative trauma. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Residual, direct and cumulative effect of zinc application on wheat and rice yield under rice-wheat syst

    Directory of Open Access Journals (Sweden)

    R. Khan

    2009-05-01

    Full Text Available Zinc (Zn deficiency is prevalent particularly on calcareous soils of arid and semiarid region. A field experiment was conducted to investigate the direct, residual and cumulative effect of zinc on the yield of wheat and rice in permanent layout for two consecutive years, 2004-05 and 2005-06 at Arid Zone Research Institute D.I. Khan. Soil under study was deficient in Zn (0.8 mg kg-1. Effect of Zn on yield, Zn concentrations in leaf and soils were assessed using wheat variety Naseer-2000 and rice variety IRRI-6. Three rates of Zn, ranging from 0 to 10 kg ha-1 in soil, were applied as zinc sulphate (ZnSO4. 7H2O along with basal dose fertilization of nitrogen, phosphorus and potassium. Mature leaf and soil samples were collected at panicle initiation stage. The results showed that grain yield of wheat and rice was significantly increased by the direct application of 5 and 10 kg Zn ha-1. Highest grain yield of wheat (5467 kg ha-1 was recorded with the direct application of 10 kg Zn ha-1 while 4994 kg ha-1 was recorded with the cumulative application of 10 kg Zn ha-1 but the yield increase due to residual effect of Zn was statistically lower than the cumulative effect of Zn. Maximum paddy yield was recorded with the cumulative application ofZn followed by residual and direct applied 10 and 5 kg Zn kg ha-1, respectively. Zn concentration in soils ranged from 0.3 to 1.5 mg kg-1 in wheat and 0.24 to 2.40 mg kg-1 in rice, while in leaves it ranged from 18-48 mg kg-1 in wheat and 15-52 mg kg-1 in rice. The concentration of Zn in soil and leaves increased due to the treatments in the order; cumulative > residual > direct effect > control (without Zn. The yield attributes like 1000- grain weight, number of spikes, spike length and plant height were increased by the residual, direct and cumulative effect of Zn levels; however, the magnitude of increase was higher in cumulative effect than residual and direct effect of Zn, respectively. Under Zn-deficient soil

  20. Twenty-years of lung transplantation in Taiwan: Effects of cumulative institutional experience on early outcomes

    Directory of Open Access Journals (Sweden)

    Shun-Mao Yang

    2017-11-01

    Conclusion: Although the results were undesirable in the first decade of the transplant program, the cumulative institutional experience led to significantly improved outcomes in the second decade of the transplant program.

  1. Cumulative Effect of Obesogenic Behaviours on Adiposity in Spanish Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Helmut Schröder

    2017-12-01

    Full Text Available Objective: Little is known about the cumulative effect of obesogenic behaviours on childhood obesity risk. We determined the cumulative effect on BMI z-score, waist-to-height ratio (WHtR, overweight and abdominal obesity of four lifestyle behaviours that have been linked to obesity. Methods: In this cross-sectional analysis, data were obtained from the EnKid sudy, a representative sample of Spanish youth. The study included 1,614 boys and girls aged 5-18 years. Weight, height and waist circumference were measured. Physical activity (PA, screen time, breakfast consumption and meal frequency were self-reported on structured questionnaires. Obesogenic behaviours were defined as z-score was computed using age- and sex-specific reference values from the World Health Organization (WHO. Overweight including obesity was defined as a BMI > 1 SD from the mean of the WHO reference population. Abdominal obesity was defined as a WHtR ≥ 0.5. Results: High screen time was the most prominent obesogenic behaviour (49.7%, followed by low physical activity (22.4%, low meal frequency (14.4%, and skipping breakfast (12.5%. Although 33% of participants were free of all 4 obesogenic behaviours, 1, 2, and 3 or 4 behaviours were reported by 44.5%, 19.3%, and 5.0%, respectively. BMI z-score and WHtR were positively associated (p < 0.001 with increasing numbers of concurrent obesogenic behaviours. The odds of presenting with obesogenic behaviours were significantly higher in children who were overweight (OR 2.68; 95% CI 1.50; 4.80 or had abdominal obesity (OR 2.12; 95% CI 1.28; 3.52; they reported more than 2 obesogenic behaviours. High maternal and parental education was inversely associated (p = 0.004 and p < 0.001, respectively with increasing presence of obesogenic behaviours. Surrogate markers of adiposity increased with numbers of concurrent presence of obesogenic behaviours. The opposite was true for high maternal and paternal education.

  2. Cumulative effects of repeated exposure to pO2 = 200 kPa (2 atm).

    Science.gov (United States)

    Shykoff, Barbara E

    2014-01-01

    Even asymptomatic exposures to elevated oxygen partial pressure (pO2) can influence subsequent exposures. Dry chamber dives of three hours' duration at pO2 of 200 kPa were conducted to examine cumulative effects. Experiments were single (n = 27), or paired exposures with surface intervals (SIs) 15 to 17 hours (n = 30), six hours (n = 33), or three hours (n = 36). Flow-volume loops, diffusing capacity, and symptoms were recorded before and after exposures. Immediately after surfacing from second exposures, some significant (p < 0.05) mean changes from baseline in pulmonary function indices occurred for all SIs and persisted for two days for three-hour SIs and for one day for 15-hour SIs. Incidences of symptoms were 15% immediately after one exposure and 28%, 38% and 31% immediately after a second exposure following 15-, six- , or three-hour SIs, respectively. Incidences of changes in pulmonary function indices (deltaPF) were 5%, 11%, 12% and 14% for single exposures or two with 15-, six-, or three-hour SIs, respectively. Two days following the second exposure, resolution of symptoms was incomplete after six- or 15-hour SIs, as was resolution of deltaPF after 15-hour SIs. The incidences indicate non-linear superposition of effects of a first and second exposure, and are not readily explained by delayed-onset injury.

  3. Radiation effects on microelectronics

    International Nuclear Information System (INIS)

    Gover, J.E.

    1987-01-01

    Applications of radiation-hardened microelectronics in nuclear power systems include (a) light water reactor (LWR) containment building, postaccident instrumentation that can operate through the beta and gamma radiation released in a design basis loss-of-coolant accident; (b) advanced LWR instrumentation and control systems employing distributed digital integrated circuit (IC) technology to achieve a high degree of artificial intelligence and thereby reduce the probability of operator error under accident conditions; (c) instrumentation, command, control and communication systems for space nuclear power applications that must operate during the neutron and gamma-ray core leakage environments as well as the background electron, proton, and heavy charged particle environments of space; and (d) robotics systems designed for the described functions. Advanced microelectronics offer advantages in cost and reliability over alternative approaches to instrumentation and control. No semiconductor technology is hard to all classes of radiation effects phenomena. As the effects have become better understood, however, significant progress has been made in hardening IC technology. Application of hardened microelectronics to nuclear power systems has lagged military applications because of the limited market potential of hardened instruments and numerous institutional impediments

  4. Radiation effect on implanted pacemakers

    International Nuclear Information System (INIS)

    Pourhamidi, A.H.

    1983-01-01

    It was previously thought that diagnostic or therapeutic ionizing radiation did not have an adverse effect on the function of cardiac pacemakers. Recently, however, some authors have reported damaging effect of therapeutic radiation on cardiac pulse generators. An analysis of a recently-extracted pacemaker documented the effect of radiation on the pacemaker pulse generator

  5. Radiation effects on polyethylenes

    International Nuclear Information System (INIS)

    Suzuki, T.; Oki, Y.; Numajiri, M.; Miura, T.; Kondo, K.; Tanabe, Y.; Ishiyama, M.; Ito, Y.

    1992-01-01

    Radiation effects on four kinds of polyethylenes were studied from the viewpoints of mechanical properties, free radicals and free volumes. The samples were irradiated using a cobalt 60 gamma source to give doses up to 3MGy. The degradation of mechanical strength due to gamma-irradiation was evaluated by the elongation at break and its tensile strength. Radiation induced free radicals were measured by ESR. Free volumes observed by the o-Ps component of the positron annihilation spectrum are normally the large ones located in the amorphous regions and after irradiation these are created in crystalline regions, too. The sizes and the relative numbers of free volumes were evaluated by lifetimes and intensities of a long-lived component of positronium, respectively. Using these data, the properties of polyethylenes before and after irradiation are discussed. (author)

  6. Biological effects of ionising radiation

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    The paper reports the proceedings of a conference organised jointly by Friends of the Earth (U.K.) and Greenpeace (International). The aim of the conference was to discuss the effects of low level radiation, particularly on man, within the terms of dose/risk relationships. The topics discussed included: sources of radiation, radiation discharges from nuclear establishments, predictive modelling of radiation hazards, radiation effects at Hiroshima, low dose effects and ICRP dose limits, variation in sensitivity to radiation, and the link between childhood cancer and nuclear power. (U.K.)

  7. Powdery Mildew Decreases the Radial Growth of Oak Trees with Cumulative and Delayed Effects over Years.

    Directory of Open Access Journals (Sweden)

    Didier Bert

    Full Text Available Quercus robur and Q. petraea are major European forest tree species. They have been affected by powdery mildew caused by Erysiphe alphitoides for more than a century. This fungus is a biotrophic foliar pathogen that diverts photosynthetate from the plant for its own nutrition. We used a dendrochronological approach to investigate the effects of different levels of infection severity on the radial growth of young oak trees. Oak infection was monitored at individual tree level, at two sites in southwestern France, over a five-year period (2001-2005. Mean infection severity was almost 75% (infected leaf area at the end of the 2001 growing season, at both sites, but only about 40% in 2002, and 8%, 5% and 2% in 2003, 2004 and 2005, respectively. Infection levels varied considerably between trees and were positively related between 2001 and 2002. Increment cores were taken from each tree to assess annual ring widths and increases in basal area. Annual radial growth was standardised to take the effect of tree size into account. Annual standardised radial growth was significantly and negatively correlated with infection severity in the same year, for both 2001 and 2002, and at both sites. The decrease in growth reached 70-90% for highly infected trees. The earlywood width was poorly correlated with infection severity, but the proportion of latewood in tree rings was lower in highly infected trees (60% than in less heavily infected trees (85%. Infection in 2001 and 2002 was found to have a cumulative effect on radial growth in these years, together with a delayed effect detectable in 2003. Thus, even non-lethal pathogens like powdery mildew can have a significant impact on tree functioning. This impact should be taken into account in growth and yield models, to improve predictions of forest net primary production.

  8. Concurrent and Sustained Cumulative Effects of Adolescent Marijuana Use on Subclinical Psychotic Symptoms.

    Science.gov (United States)

    Bechtold, Jordan; Hipwell, Alison; Lewis, David A; Loeber, Rolf; Pardini, Dustin

    2016-08-01

    Adolescents who regularly use marijuana may be at heightened risk of developing subclinical and clinical psychotic symptoms. However, this association could be explained by reverse causation or other factors. To address these limitations, the current study examined whether adolescents who engage in regular marijuana use exhibit a systematic increase in subclinical psychotic symptoms that persists during periods of sustained abstinence. The sample comprised 1,009 boys who were recruited in 1st and 7th grades. Self-reported frequency of marijuana use, subclinical psychotic symptoms, and several time-varying confounds (e.g., other substance use, internalizing/externalizing problems) were recorded annually from age 13 to 18. Fixed-effects (within-individual change) models examined whether adolescents exhibited an increase in their subclinical psychotic symptoms as a function of their recent and/or cumulative history of regular marijuana use and whether these effects were sustained following abstinence. Models controlled for all time-stable factors (default) and several time-varying covariates as potential confounds. For each year adolescent boys engaged in regular marijuana use, their expected level of subsequent subclinical psychotic symptoms rose by 21% and their expected odds of experiencing subsequent subclinical paranoia or hallucinations rose by 133% and 92%, respectively. The effect of prior regular marijuana use on subsequent subclinical psychotic symptoms persisted even when adolescents stopped using marijuana for a year. These effects were after controlling for all time-stable and several time-varying confounds. No support was found for reverse causation. These results suggest that regular marijuana use may significantly increase the risk that an adolescent will experience persistent subclinical psychotic symptoms.

  9. Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6-11 years-old than cumulative high doses of inhaled terbutaline.

    Science.gov (United States)

    Kaae, Rikke; Agertoft, Lone; Pedersen, Sören; Nordvall, S Lennart; Pedroletti, Christophe; Bengtsson, Thomas; Johannes-Hellberg, Ingegerd; Rosenborg, Johan

    2004-10-01

    To evaluate high dose tolerability and relative systemic dose potency between inhaled clinically equipotent dose increments of formoterol and terbutaline in children. Twenty boys and girls (6-11 years-old) with asthma and normal ECGs were studied. Ten doses of formoterol (Oxis) 4.5 microg (F4.5) or terbutaline (Bricanyl) 500 microg (T500) were inhaled cumulatively via a dry powder inhaler (Turbuhaler) over 1 h (three patients) or 2.5 h (17 patients) and compared to a day of no treatment, in a randomised, double-blind (active treatments only), crossover trial. Blood pressure (BP), ECG, plasma potassium, glucose, lactate, and adverse events were monitored up to 10 h to assess tolerability and relative systemic dose potency. Formoterol and terbutaline had significant beta2-adrenergic effects on most outcomes. Apart from the effect on systolic BP, QRS duration and PR interval, the systemic effects were significantly more pronounced with terbutaline than with formoterol. Thus, mean minimum plasma potassium, was suppressed from 3.56 (95% confidence interval, CI: 3.48-3.65) mmol l(-1) on the day of no treatment to 2.98 (CI: 2.90-3.08) after 10 x F4.5 and 2.70 (CI: 2.61-2.78) mmol l(-1) after 10 x T500, and maximum Q-Tc (heart rate corrected Q-T interval [Bazett's formula]) was prolonged from 429 (CI: 422-435) ms on the day of no treatment, to 455 (CI: 448-462) ms after 10 x F4.5 and 470 (CI: 463-476) ms after 10 x T500. Estimates of relative dose potency indicated that F4.5 microg had the same systemic activity as the clinically less effective dose of 250 microg terbutaline. The duration of systemic effects differed marginally between treatments. Spontaneously reported adverse events (most frequently tremor) were fewer with formoterol (78% of the children) than with terbutaline (95%). A serious adverse event occurred after inhalation of 45 microg formoterol over the 1 h dosing time, that prompted the extension of dosing time to 2.5 h. Multiple inhalations over 2.5 h of

  10. Cumulative high doses of inhaled formoterol have less systemic effects in asthmatic children 6–11 years-old than cumulative high doses of inhaled terbutaline

    Science.gov (United States)

    Kaae, Rikke; Agertoft, Lone; Pedersen, Sören; Nordvall, S Lennart; Pedroletti, Christophe; Bengtsson, Thomas; Johannes-Hellberg, Ingegerd; Rosenborg, Johan

    2004-01-01

    Objectives To evaluate high dose tolerability and relative systemic dose potency between inhaled clinically equipotent dose increments of formoterol and terbutaline in children. Methods Twenty boys and girls (6–11 years-old) with asthma and normal ECGs were studied. Ten doses of formoterol (Oxis®) 4.5 µg (F4.5) or terbutaline (Bricanyl®) 500 µg (T500) were inhaled cumulatively via a dry powder inhaler (Turbuhaler®) over 1 h (three patients) or 2.5 h (17 patients) and compared to a day of no treatment, in a randomised, double-blind (active treatments only), crossover trial. Blood pressure (BP), ECG, plasma potassium, glucose, lactate, and adverse events were monitored up to 10 h to assess tolerability and relative systemic dose potency. Results Formoterol and terbutaline had significant β2-adrenergic effects on most outcomes. Apart from the effect on systolic BP, QRS duration and PR interval, the systemic effects were significantly more pronounced with terbutaline than with formoterol. Thus, mean minimum plasma potassium, was suppressed from 3.56 (95% confidence interval, CI: 3.48–3.65) mmol l−1 on the day of no treatment to 2.98 (CI: 2.90–3.08) after 10 × F4.5 and 2.70 (CI: 2.61–2.78) mmol l−1 after 10 × T500, and maximum Q-Tc (heart rate corrected Q-T interval [Bazett's formula]) was prolonged from 429 (CI: 422–435) ms on the day of no treatment, to 455 (CI: 448–462) ms after 10 × F4.5 and 470 (CI: 463–476) ms after 10 × T500. Estimates of relative dose potency indicated that F4.5 µg had the same systemic activity as the clinically less effective dose of 250 µg terbutaline. The duration of systemic effects differed marginally between treatments. Spontaneously reported adverse events (most frequently tremor) were fewer with formoterol (78% of the children) than with terbutaline (95%). A serious adverse event occurred after inhalation of 45 µg formoterol over the 1 h dosing time, that prompted the extension of dosing time to 2.5 h

  11. Biological radiation effects

    International Nuclear Information System (INIS)

    Koggl, D.; Dedenkov, A.N.

    1986-01-01

    All nowadays problems of radio biology are considered: types of ionizing radiations, their interaction with material; damage of molecular structures and their reparation; reaction of cells and their recovery from radiation damage; reaction of the whole organism and its separate systems. Particular attention is given to the problems of radiation carcinogenesis and radiation hazard for man

  12. Effects of background radiation

    International Nuclear Information System (INIS)

    Knox, E.G.; Stewart, A.M.; Gilman, E.A.; Kneale, G.W.

    1987-01-01

    The primary objective of this investigation is to measure the relationship between exposure to different levels of background gamma radiation in different parts of the country, and different Relative Risks for leukaemias and cancers in children. The investigation is linked to an earlier analysis of the effects of prenatal medical x-rays upon leukaemia and cancer risk; the prior hypothesis on which the background-study was based, is derived from the earlier results. In a third analysis, the authors attempted to measure varying potency of medical x-rays delivered at different stages of gestation and the results supply a link between the other two estimates. (author)

  13. Radiation effects on vasoproliferation

    International Nuclear Information System (INIS)

    Yamaura, Hirotsugu; Matsuzawa, Taiju

    1975-01-01

    The authors quantitatively examined radiation effects on vascular proliferarion, using the rat transparent chamber technique to observe the living microcirculation. We studied the process of vasoproliferation and revascularization from the surrounding pre-existing vessels into the surgically avascularized area in the chamber, by measuring the vascular lenght photographically. A hyper-vascularized zone, about 0.5 mm in with, was formed on the vascularizing frontier, the significance of which is so far not known. When the chambers were irradiated with various doses of 60 Co γ-rays, a dose dependent inhibition of vasoproliferation was observed. (auth.)

  14. Radiation effects on vasoproliferation

    Energy Technology Data Exchange (ETDEWEB)

    Yamaura, H; Matsuzawa, T [Tohoku Univ., Sendai (Japan). Research Inst. for Tuberculosis, Leprosy and Cancer

    1975-06-01

    The authors quantitatively examined radiation effects on vascular proliferarion, using the rat transparent chamber technique to observe the living microcirculation. We studied the process of vasoproliferation and revascularization from the surrounding pre-existing vessels into the surgically avascularized area in the chamber, by measuring the vascular lenght photographically. A hyper-vascularized zone, about 0.5 mm in with, was formed on the vascularizing frontier, the significance of which is so far not known. When the chambers were irradiated with various doses of /sup 60/Co ..gamma..-rays, a dose dependent inhibition of vasoproliferation was observed.

  15. Cumulative effect assessment in Canada: a regional framework for aquatic ecosystems

    International Nuclear Information System (INIS)

    Dube, Monique G.

    2003-01-01

    Sustainable development of the aquatic environment depends upon routine and defensible cumulative effects assessment (CEA). CEA is the process of predicting the consequences of development relative to an assessment of existing environmental quality. Theoretically, it provides an on-going mechanism to evaluate if levels of development exceed the environment's assimilative capacity; i.e., its ability to sustain itself. In practice, the link between CEA and sustainable development has not been realized because CEA concepts and methods have developed along two dichotomous tracks. One track views CEA as an extension of the environmental assessment (EA) process for project developments. Under this track, stressor-based (S-B) methods have been developed where the emphasis is on local, project-related stressors, their link with aquatic indicators, and the potential for environmental effects through stressor-indicator interactions. S-B methods focus on the proposed development and prediction of project-related effects. They lack a mechanism to quantify existing aquatic quality especially at scales broader than an isolated development. This limitation results in the prediction of potential effects relative to a poorly defined baseline state. The other track views CEA as a broader, regional assessment tool where effects-based (E-B) methods specialize in quantification of existing aquatic effects over broad spatial scales. However, the predictive capabilities of E-B methods are limited because they are retrospective, i.e., the stressor causing the effect is identified after the effect has been measured. When used in isolation, S-B and E-B methods do not address CEA in the context necessary for sustainable development. However, if the strengths of these approaches were integrated into a holistic framework for CEA, an operational mechanism would exist to better monitor and assess sustainable development of our aquatic resources. This paper reviews the existing conceptual basis

  16. Review of radiation effects in solid-nuclear-waste forms

    International Nuclear Information System (INIS)

    Weber, W.J.

    1981-09-01

    Radiation effects on the stability of high-level nuclear waste (HLW) forms are an important consideration in the development of technology to immobilize high-level radioactive waste because such effects may significantly affect the containment of the radioactive waste. Since the required containment times are long (10 3 to 10 6 years), an understanding of the long-term cumulative effects of radiation damage on the waste forms is essential. Radiation damage of nuclear waste forms can result in changes in volume, leach rate, stored energy, structure/microstructure, and mechanical properties. Any one or combination of these changes might significantly affect the long-term stability of the nuclear waste forms. This report defines the general radiation damage problem in nuclear waste forms, describes the simulation techniques currently available for accelerated testing of nuclear waste forms, and reviews the available data on radiation effects in both glass and ceramic (primarily crystalline) waste forms. 76 references

  17. Cumulative effects of rapid climate and land-use changes on the Yamal Peninsula, Russia

    Science.gov (United States)

    Walker, D. A.; Leibman, M. O.; Forbes, B. C.; Epstein, H. E.

    2008-12-01

    Our principal goal is to develop better, more far-looking tools to predict the cumulative effects of resource development, climate-change, and traditional land use. Here we use remote sensing, climate-change analyses, socio-economic analyses, and vegetation-change models to examine the cumulative effects of climate change, gas development, and reindeer herding on the Yamal Peninsula in northwest Siberia as part of the Northern Eurasia Earth Science Partnership Initiative (NEESPI). We find: 1. Direct (planned) impacts of industrial activities on the Yamal Peninsula are currently local and limited in extent, but this is changing rapidly as extensive gas fields are developed and land and sea transportation corridors are developed to get the gas to market. Indirect impacts of the development at Bovanenkovo, the largest gas field, exceed the direct impacts by a factor of three, and the total area of influence of the development on the reindeer pasturelands (e.g., area where migration routes and access to pasturelands is affected) exceeds the direct impacts by a factor of about 40. 2. The trend in land-surface temperatures has co-varied with the trend in sea-ice. Low sea ice in the preceding December-March period is correlated to warmer land temperature the following summer. The sea- ice trends in the Kara Sea-Yamal region are tied to variation in the North Atlantic Oscillation index. 4. Only a small greening response to warming has been detected on the Yamal in comparison with some other areas in the Arctic (e.g. Northern Alaska). The actual effects of climate-change on vegetation are currently hard to document at the ground level because of lack of baseline and long-term ground observations and difficulty of excluding reindeer in these studies. 5. There is high potential for extensive landscape effects due to unstable sandy soils, and extremely ice-rich permafrost near the surface on slopes. 6. Two different vegetation modeling approaches are being used to predict

  18. Biological radiation effects

    International Nuclear Information System (INIS)

    Sejourne, Michele.

    1977-01-01

    This work examines ionizing radiations: what they are, where they come from, their actions and consequences, finally the norms and preventive measures necessary to avoid serious contamination, whether the individual or the population in general is involved. Man has always been exposed to natural irradiation, but owing to the growing use of ionizing radiations both in medicine and in industry, not to mention nuclear tests and their use as an argument of dissuasion, the irradiation of human beings is increasing daily. Radioactive contamination does remain latent, apart from acute cases, but this is where the danger lies since the consequences may not appear until long after the irradiation. Of all biological effects due to the action of radioelements the genetic risk is one of the most important, affecting the entire population and especially the generations to come. The risk of cancer and leukemia induction plays a substantial part also since a large number of people may be concerned, depending on the mode of contamination involved. All these long-term dangers do not of course exclude the various general or local effects to which the individual alone may be exposed and which sometimes constitute a threat to life. As a result the use of ionizing radiations must be limited and should only be involved if no other process can serve instead. The regulations governing radioelements must be stringent and their application strictly supervised for the better protection of man. This protection must be not only individual but also collective since pollution exists in air, water and land passes to plants and animals and finally reaches the last link in the food chain, man [fr

  19. Radiation effects and radiation risks. 2. ed.

    International Nuclear Information System (INIS)

    Lengfelder, E.; Forst, D.; Feist, H.; Pratzel, H.G.

    1990-01-01

    The book presents the facts and the principles of assessment and evaluation of biological radiation effects in general and also with particular reference to the reactor accident of Chernobyl, reviewing the consequences and the environmental situation on the basis of current national and international literature, including research work by the authors. The material compiled in this book is intended especially for physicians, but will also prove useful for persons working in the public health services, in administration, or other services taking care of people. The authors tried to find an easily comprehensible way of presenting and explaining the very complex processes and mechanisms of biological radiation effects and carcinogenesis, displaying the physical primary processes and the mechanisms of the molecular radiation effects up to the effects of low-level radiation, and present results of comparative epidemiologic studies. This section has been given considerable space, in proportion to its significance. It also contains literature references for further reading, offering more insight and knowledge of aspects of special subject fields. The authors also present less known results and data and discuss them against the background of well-known research results and approaches. Apart from the purpose of presenting comprehensive information, the authors intend to give an impact for further thinking about the problems, and helpful tools for independent decisions and action on the basis of improved insight and assessment, and in this context particularly point to the problems induced by the Chernobyl reactor accident. (orig.) With 10 maps in appendix [de

  20. Effects of radiation

    International Nuclear Information System (INIS)

    Masse, R.

    2006-01-01

    The medical consequences of a whole-body irradiation come from the destruction of cells and inflammatory reactions it provokes. The most sensitive organs are the tissues that actively split. The embryo is particularly sensitive, from 200 mSv for the effects on the brain development. The reproduction functions are reached for man from 2000 mSv, the ovary sensitivity is less, the oocytes do not split after the fetus life. For adult the bone marrow outrage leads to the disappearing of blood cells (4000 mSv). The doses from 6000 to 10000 mSv lead the failure of the digestive system and lung. for the upper doses every tissue is reached, particularly by the effects on cells of blood vessels. Important brain dysfunctions appear beyond 10000 mSv. As regards the delayed effects of overexposures the epidemiology brings to light sanitary consequences of the exposure of the population to the ionizing radiations and requires that all the possible factors associated for that purpose are considered. About hereditary effects, it appears that moderate acute radiation exposures of even a relatively large human population must have little impact, in spite of the rate of spontaneous congenital deformations is of the order of 6 %. For the induction of cancers, it is not observed excess for doses lower than 200 mSv for adults and 100 mSv for children (the populations studied are survival people of hiroshima and Nagasaki, patients treated by irradiation, uranium miners, children exposed to radioactive iodine after Chernobylsk accident). To simplify an expression of the risk has been fixed to 5% of induced cancer by Sv for population and 4% by Sv for workers, the different being explained by the demography and the sensitivity of the youngest age groups. As regards the low doses of radiations, a bundle of convergent epidemiological observations notices the absence of effects of the low doses rates. Biological mechanisms, notably of repair are approached, then certain accidents (Goiania

  1. Indirect Effects and Potential Cumulative Impacts of Dredging in an Urbanized Estuary

    Science.gov (United States)

    Sommerfield, C. K.; Chen, J.; Ralston, D. K.; Geyer, W. R.

    2016-02-01

    For over two centuries, the Delaware River and Bay estuary has supported one of the most economically important ports in the United States. To accommodate ships of ever-increasing size, the 165-km axial shipping channel has been deepened to over twice the natural depth of the estuary. While it is known that the channel has modified tides and sedimentation patterns in the estuary, unknown are the impacts on the ecosystem as a whole. A concern is the influence of channelization on sediment movement to the tidal wetland coast, which is eroding at rates on the order of meters per year. Tidal wetlands frame the entire estuary and provide vital ecosystem services ranging from recreation to carbon sequestration. To identify shifts in baseline conditions, we are performing a retrospective analysis of estuarine dynamics using historical bathymetry, numerical modeling, and observational studies. The period of interest extends from 1848 (50 years prior to channel construction) to present. During this period the channel was progressively deepened from its natural depth of 5.5 m to the current depth of 14 m. Preliminary modeling results support independent evidence that the salt intrusion and zone of rapid sediment deposition migrated several 10s of kilometers up-estuary as an indirect effect of deepening. Ironically, the locus of intense deposition now falls squarely within the Wilmington-Philadelphia port complex; river sediment that initially settles in this area is removed by maintenance dredging before it can disperse seaward. Sediment budgetary analysis indicates that the mass of sediment dredged from the upper estuary on average exceeds the mass of the new sediment supplied from the drainage basin. Hence, a probable cumulative impact of dredging is a reduction in sediment delivery to the lower estuary and fringing wetlands. Connections among the shipping channel, wave-tide interactions, and marsh edge erosion are a topic of ongoing modeling and observational research.

  2. Cumulative Effects of Neighborhood Social Adversity and Personal Crime Victimization on Adolescent Psychotic Experiences.

    Science.gov (United States)

    Newbury, Joanne; Arseneault, Louise; Caspi, Avshalom; Moffitt, Terrie E; Odgers, Candice L; Fisher, Helen L

    2018-02-15

    Little is known about the impact of urbanicity, adverse neighborhood conditions and violent crime victimization on the emergence of adolescent psychotic experiences. Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally-representative cohort of 2232 British twins who were interviewed about adolescent psychotic experiences at age 18. Urbanicity, neighborhood characteristics, and personal victimization by violent crime were measured during childhood and adolescence via geocoded census data, surveys of over 5000 immediate neighbors of the E-Risk participants, and interviews with participants themselves. Adolescents raised in urban vs rural neighborhoods were significantly more likely to have psychotic experiences (OR = 1.67, 95% CI = 1.21-2.30, P = .002). This association remained significant after considering potential confounders including family socioeconomic status, family psychiatric history, and adolescent substance problems (OR = 1.43, 95% CI = 1.01-2.03, P = .042), but became nonsignificant after considering adverse social conditions in urban neighborhoods such as low social cohesion and high neighborhood disorder (OR = 1.35, 95% CI = 0.94-1.92, P = .102). The combined association of adverse neighborhood social conditions and personal crime victimization with adolescent psychotic experiences (adjusted OR = 4.86, 95% CI = 3.28-7.20, P < .001) was substantially greater than for either exposure alone, highlighting a potential interaction between neighborhood conditions and crime victimization (interaction contrast ratio = 1.81, 95% CI = -0.03 to 3.65) that was significant at the P = .054 level. Cumulative effects of adverse neighborhood social conditions and personal victimization by violent crime during upbringing partly explain why adolescents in urban settings are more likely to report psychotic experiences. Early intervention efforts for psychosis could be targeted towards victimized youth living in urban and socially

  3. Cumulative Effects of Neighborhood Social Adversity and Personal Crime Victimization on Adolescent Psychotic Experiences

    Science.gov (United States)

    Newbury, Joanne; Arseneault, Louise; Caspi, Avshalom; Moffitt, Terrie E; Odgers, Candice L

    2018-01-01

    Abstract Background: Little is known about the impact of urbanicity, adverse neighborhood conditions and violent crime victimization on the emergence of adolescent psychotic experiences. Methods: Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally-representative cohort of 2232 British twins who were interviewed about adolescent psychotic experiences at age 18. Urbanicity, neighborhood characteristics, and personal victimization by violent crime were measured during childhood and adolescence via geocoded census data, surveys of over 5000 immediate neighbors of the E-Risk participants, and interviews with participants themselves. Results: Adolescents raised in urban vs rural neighborhoods were significantly more likely to have psychotic experiences (OR = 1.67, 95% CI = 1.21–2.30, P = .002). This association remained significant after considering potential confounders including family socioeconomic status, family psychiatric history, and adolescent substance problems (OR = 1.43, 95% CI = 1.01–2.03, P = .042), but became nonsignificant after considering adverse social conditions in urban neighborhoods such as low social cohesion and high neighborhood disorder (OR = 1.35, 95% CI = 0.94–1.92, P = .102). The combined association of adverse neighborhood social conditions and personal crime victimization with adolescent psychotic experiences (adjusted OR = 4.86, 95% CI = 3.28–7.20, P crime victimization (interaction contrast ratio = 1.81, 95% CI = −0.03 to 3.65) that was significant at the P = .054 level. Conclusions: Cumulative effects of adverse neighborhood social conditions and personal victimization by violent crime during upbringing partly explain why adolescents in urban settings are more likely to report psychotic experiences. Early intervention efforts for psychosis could be targeted towards victimized youth living in urban and socially adverse neighborhoods. PMID:28535284

  4. Subjective Effect of September 11, 2001 among Pregnant Women: Is Cumulative History of Interpersonal Violence Important?

    Science.gov (United States)

    Lewis, Marilyn W.; Cavanagh, Paul K.; Ahn, Grace; Yoshioka, Marianne R.

    2008-01-01

    Prior history of trauma may sensitize individuals to subsequent trauma, including terrorist attacks. Using a convenience sample of secondary, cross-sectional data, pregnant women were grouped based on lifetime interpersonal violence history. Cumulative risk theory was used to evaluate the association of lifetime interpersonal violence history and…

  5. Language Delay in Severely Neglected Children: A Cumulative or Specific Effect of Risk Factors?

    Science.gov (United States)

    Sylvestre, Audette; Merette, Chantal

    2010-01-01

    Objectives: This research sought to determine if the language delay (LD) of severely neglected children under 3 years old was better explained by a cumulative risk model or by the specificity of risk factors. The objective was also to identify the risk factors with the strongest impact on LD among various biological, psychological, and…

  6. Effects of Cumulative Family Risk Factors on American Students' Academic Performance

    Science.gov (United States)

    Dunst, Carl J.; Hamby, Deborah W.

    2016-01-01

    The relationships between cumulative family risk factors and American students' academic performance were examined in all 50 States and the District of Columbia. Data from the 2007 "American Community Survey" were used to ascertain the percent of birth to 18 year old children in the United States who experienced three or more risk…

  7. Cumulative effects analysis of the water quality risk of herbicides used for site preparation in the Central North Island, New Zealand

    Science.gov (United States)

    Dan Neary; Brenda R. Baillie

    2016-01-01

    Herbicide use varies both spatially and temporally within managed forests. While information exists on the effects of herbicide use on water quality at the site and small catchment scale, little is known about the cumulative effects of herbicide use at the landscape scale. A cumulative effects analysis was conducted in the upper Rangitaiki catchment (118,345...

  8. Radiation effects on Brassica seeds and seedlings

    Science.gov (United States)

    Deoli, Naresh; Hasenstein, Karl H.

    2016-07-01

    Space radiation consists of high energy charged particles and affects biological systems, but because of its stochastic, non-directional nature is difficult to replicate on Earth. Radiation damages biological systems acutely at high doses or cumulatively at low doses through progressive changes in DNA organization. These damages lead to death or cause of mutations. While radiation biology typically focuses on mammalian or human systems, little is known as to how radiation affects plants. In addition, energetic ion beams are widely used to generate new mutants in plants considering their high-LET (Linear Energy Transfer) as compared to gamma rays and X-rays. Understanding the effect of ionizing radiation on plant provides a basis for studying effects of radiation on biological systems and will help mitigate (space) radiation damage in plants. We exposed dry and imbibed Brassica rapa seeds and seedling roots to proton beams of varying qualities and compared the theoretical penetration range of different energy levels with observable growth response. We used 1, 2 and 3 MeV protons in air at the varying fluences to investigate the effect of direct irradiation on the seeds (1012 - 1015 ions/cm2) and seedlings (1013 ions/cm2). The range of protons in the tissue was calculated using Monte-Carlo based SRIM (Stopping and Range of Ions in Matter) software. The simulation and biological results indicate that ions did not penetrate the tissue of dry or hydrated seeds at all used ion energies. Therefore the entire energy was transferred to the treated tissue. Irradiated seeds were germinated vertically under dim light and roots growth was observed for two days after imbibition. The LD50 of the germination was about 2×1014 ions/cm2 and about 5×1014 ions/cm2 for imbibed and dry seeds, respectively. Since seedlings are most sensitive to gravity, the change in gravitropic behavior is a convenient means to assess radiation damage on physiological responses other than direct tissue

  9. Radiation effects on living systems

    International Nuclear Information System (INIS)

    Hawley, N.J.

    1984-04-01

    This bibliography includes papers and reports by Atomic Energy of Canada Limited scientists concerning radiation effects on living systems. It is divided into three sections: Radiobiology, Radiation Biochemistry and Radiation Chemistry. It is intended that the bibliography will be updated regularly

  10. Radiation effects in optoelectronic devices

    International Nuclear Information System (INIS)

    Barnes, C.E.

    1977-03-01

    A summary is given of studies on radiation effects in light-emitting diodes, laser diodes, detectors, optical isolators and optical fibers. It is shown that the study of radiation damage in these devices can provide valuable information concerning the nature of the devices themselves, as well as methods of hardening these devices for applications in radiation environments

  11. Genetic effects of ionising radiation

    International Nuclear Information System (INIS)

    Saunders, P.A.H.

    1991-12-01

    Ionizing radiation effects on the gem cells, which can result in genetic abnormalities, are described. The basic mechanisms of radiation interactions with chromosomes, or specifically DNA, which can result in radiation induced mutation are discussed. Methods of estimating genetic risks, and some values for quantitative risk estimates are given. (U.K.). 13 refs., 2 figs., 1 tab

  12. Biological effects of particle radiation

    International Nuclear Information System (INIS)

    Sakamoto, Kiyohiko

    1988-01-01

    Conventional radiations such as photons, gamma rays or electrons show several physical or biological disadvantages to bring tumors to cure, therefore, more and more attentions is being paid to new modalitie such as fast neutrons, protons, negative pions and heavy ions, which are expected to overcome some of the defects of the conventional radiations. Except for fast neutrons, these particle radiations show excellet physical dose localization in tissue, moreover, in terms of biological effects, they demonstrate several features compared to conventional radiations, namely low oxygen enhancement ratio, high value of relative biological effectiveness, smaller cellular recovery, larger therapeutic gain factor and less cell cycle dependency in radiation sensitivity. In present paper the biological effects of particle radiations are shown comparing to the effects of conventional radiations. (author)

  13. Biology of ionizing radiation effects

    International Nuclear Information System (INIS)

    Ferradini, C.; Pucheault, J.

    1983-01-01

    The present trends in biology of ionizing radiation are reviewed. The following topics are investigated: interaction of ionizing radiations with matter; the radiolysis of water and aqueous solutions; properties of the free radicals intervening in the couples O 2 /H 2 O and H 2 O/H 2 ; radiation chemistry of biological compounds; biological effects of ionizing radiations; biochemical mechanisms involving free radicals as intermediates; applications (biotechnological applications, origins of life) [fr

  14. The biological effects of radiation

    International Nuclear Information System (INIS)

    Sykes, D.A.

    1979-01-01

    The hazards of radiations to man are briefly covered in this paper. The natural background sources of radiations are stated and their resulting doses are compared to those received voluntarily by man. The basis of how radiations cause biological damage is given and the resulting somatic effects are shown for varying magnitude of dose. Risk estimates are given for cancer induction and genetic effects are briefly discussed. Finally four case studies of radiation damage to humans are examined exemplifying the symptoms of large doses of radiations [af

  15. Radiation effects on lymphocytes

    International Nuclear Information System (INIS)

    Roser, B.

    1976-01-01

    This review of the ontogeny of lymphocyte populations concentrates on sites of production, rates of production, and the factors governing the differentiation and longevity of the various lymphocyte pools. The physiology of the lymphocyte pools is described with particular emphasis on recirculation from blood to lymph through lymphoid tissues. The separate routes of recirculation of both thymus-derived and nonthymus-derived lymphocytes and the possible anatomical sites and mechanisms of lymphocyte cooperation are discussed. Radiation effects on lymphocyte populations are divided into two sections. First, the effects of whole-body irradiation on the total lymphocyte pools are discussed including the differential effects of irradiation on T lymphocytes, B lymphocytes, lymphoblasts, and plasma cells. The differential sensitivity of various types of immune response is correlated, where possible, with the differential sensitivity of the lymphocyte types involved. Second, experimental attempts to selectively deplete discrete subpopulations of the total lymphocyte pools, e.g., recirculating cells, are briefly discussed with particular emphasis on studies on the effects of the localization of radionuclides in lymphoid tissue

  16. Biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    Experiments with small animals, tissue cultures, and inanimate materials help with understanding the effects of ionizing radiation that occur at the molecular level and cause the gross effects observed in man. Topics covered in this chapter include the following: Radiolysis of Water; Radiolysis of Organic Compounds; Radiolysis in Cells; Radiation Exposure and Dose Units; Dose Response Curves; Radiation Effects in Animals; Factors Affecting Health Risks. 8 refs., 3 figs., 5 tabs

  17. Effects of radiation on man

    International Nuclear Information System (INIS)

    Saunders, P.A.H.

    1981-01-01

    The available evidence on the effects of radiation on man and the predictions that have been made of possible low level effects are reviewed. Data from United Nations Scientific Committee of the Effects of Atomic Radiation (UNSCEAR) and the committee on the Biological Effects of Ionising Radiation (BEIR) is used to illustrate the acute, delayed and hereditary effects of high dose levels. The effects of low dose levels are discussed on the assumption that both somatic and hereditary effects can be predicted on the basis of linear extrapolation from high dose effects. (U.K.)

  18. CUMULATIVE REPRODUCTIVE EFFECTS OF IN UTERO ADMINISTRATION OF A MIXTURE OF TEN “ANTIANDROGENS” IN MALE SD RATS: SYNERGY OR ADDITIVITY?

    Science.gov (United States)

    In 1996, the USEPA was charged under FQPA to consider the cumulative effects of chemicals in their risk assessments. We are conducting studies to provide a framework for assessing the cumulative effects of antiandrogens. In the current study, ten “antiandrogenic” chemicals were a...

  19. Health effects of ionizing radiation

    International Nuclear Information System (INIS)

    Pathak, B.

    1989-12-01

    Ionizing radiation is energy that travels through space as electromagnetic waves or a stream of fast moving particles. In the workplace, the sources of ionizing radiation are radioactive substances, nuclear power plants, x-ray machines and nuclear devices used in medicine, research and industry. Commonly encountered types of radiation are alpha particles, beta particles and gamma rays. Alpha particles have very little penetrating power and pose a risk only when the radioactive substance is deposited inside the body. Beta particles are more penetrating than alpha particles and can penetrate the outer body tissues causing damage to the skin and the eyes. Gamma rays are highly penetrating and can cause radiation damage to the whole body. The probability of radiation-induced disease depends on the accumulated amount of radiation dose. The main health effects of ionizing radiation are cancers in exposed persons and genetic disorders in the children, grandchildren and subsequent generations of the exposed parents. The fetus is highly sensitive to radiation-induced abnormalities. At high doses, radiation can cause cataracts in the eyes. There is no firm evidence that ionizing radiation causes premature aging. Radiation-induced sterility is highly unlikely for occupational doses. The data on the combined effect of ionizing radiation and other cancer-causing physical and chemical agents are inconclusive

  20. Chemical effects of radiation

    International Nuclear Information System (INIS)

    Philips, G.O.

    1986-01-01

    Ionizing radiations initiate chemical changes in materials because of the high energy of their quanta. In water, highly reactive free radicals are produced which can initiate secondary changes of solutes, and in chemical of biological molecules in contact with the water. Free radicals can also be directly produced in irradiated medical products. Their fate can be identified and the molecular basis of radiation inactivation clarified. Methods have now been developed to protect and minimise such radiation damage. (author)

  1. The Effect of Lifting Speed on Cumulative and Peak Biomechanical Loading for Symmetric Lifting Tasks

    Directory of Open Access Journals (Sweden)

    Kasey O. Greenland

    2013-06-01

    Conclusion: Based on peak values, BCF is highest for fast speeds, but the BCF cumulative loading is highest for slow speeds, with the largest difference between fast and slow lifts. This may imply that a slow lifting speed is at least as hazardous as a fast lifting speed. It is important to consider the duration of lift when determining risks for back and shoulder injuries due to lifting and that peak values alone are likely not sufficient.

  2. Cumulative Small Effect Genetic Markers and the Risk of Colorectal Cancer in Poland, Estonia, Lithuania, and Latvia

    Directory of Open Access Journals (Sweden)

    Pablo Serrano-Fernandez

    2015-01-01

    Full Text Available The continued identification of new low-penetrance genetic variants for colorectal cancer (CRC raises the question of their potential cumulative effect among compound carriers. We focused on 6 SNPs (rs380284, rs4464148, rs4779584, rs4939827, rs6983267, and rs10795668, already described as risk markers, and tested their possible independent and combined contribution to CRC predisposition. Material and Methods. DNA was collected and genotyped from 2330 unselected consecutive CRC cases and controls from Estonia (166 cases and controls, Latvia (81 cases and controls, Lithuania (123 cases and controls, and Poland (795 cases and controls. Results. Beyond individual effects, the analysis revealed statistically significant linear cumulative effects for these 6 markers for all samples except of the Latvian one (corrected P value = 0.018 for the Estonian, corrected P value = 0.0034 for the Lithuanian, and corrected P value = 0.0076 for the Polish sample. Conclusions. The significant linear cumulative effects demonstrated here support the idea of using sets of low-risk markers for delimiting new groups with high-risk of CRC in clinical practice that are not carriers of the usual CRC high-risk markers.

  3. Cumulative risk effects for the development of behaviour difficulties in children and adolescents with special educational needs and disabilities.

    Science.gov (United States)

    Oldfield, Jeremy; Humphrey, Neil; Hebron, Judith

    2015-01-01

    Research has identified multiple risk factors for the development of behaviour difficulties. What have been less explored are the cumulative effects of exposure to multiple risks on behavioural outcomes, with no study specifically investigating these effects within a population of young people with special educational needs and disabilities (SEND). Furthermore, it is unclear whether a threshold or linear risk model better fits the data for this population. The sample included 2660 children and 1628 adolescents with SEND. Risk factors associated with increases in behaviour difficulties over an 18-month period were summed to create a cumulative risk score, with this explanatory variable being added into a multi-level model. A quadratic term was then added to test the threshold model. There was evidence of a cumulative risk effect, suggesting that exposure to higher numbers of risk factors, regardless of their exact nature, resulted in increased behaviour difficulties. The relationship between risk and behaviour difficulties was non-linear, with exposure to increasing risk having a disproportionate and detrimental impact on behaviour difficulties in child and adolescent models. Interventions aimed at reducing behaviour difficulties need to consider the impact of multiple risk variables. Tailoring interventions towards those exposed to large numbers of risks would be advantageous. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Diffusion effects in undulator radiation

    Directory of Open Access Journals (Sweden)

    Ilya Agapov

    2014-11-01

    Full Text Available Quantum diffusion effects in undulator radiation in semiclassical approximation are considered. Short-term effects on the electron beam motion are discussed and it is shown that approaches based on diffusion approximation with drift-diffusion coefficients derived from undulator or bending magnet radiation spectrum, and on Poisson statistics with radiation spectrum defined by the local beding field, all lead to similar results in terms of electron energy spread for cases of practical interest. An analytical estimate of the influence of quantum diffusion on the undulator radiation spectrum is derived.

  5. Radiation effect on polytetrafluoroethylene

    International Nuclear Information System (INIS)

    Deng Pengyang; Zhong Xiaoguang; Sun Jiazhen

    1999-01-01

    Polytetrafluoroethylene (PTFE) has always been regarded as a typical kind of radiation degradation polymer. But, in fact, PTFE can be induced crosslinking by γ-ray or electron beam at some special conditions (free oxygen and a narrow temperature region at 335 +- 5 degree C). Compared with radiation degradiation PTFE, cosslinking PTFE owns a lot of new properties. Some articles concerning with these have been published, which will be systematically reviewed in this

  6. Cumulative damage effect of 32P-colloidal chromic phosphate interstitial delivery on beagles

    International Nuclear Information System (INIS)

    Nie Qi; Liu Lu; Liu Zhiyong; Huang Peilin; Lan Xinghao; Gao Hailin; Wu Qinghua; Sun Jin; Huang Ying

    2010-01-01

    necrosis in 4 weeks, and the massive liver cells balloon type changes in 6 weeks, as well as obvious hyperemia dropsy and the hepatic lobe structure unclear in 370 MBq liver group. For the radioactive counts of urine and excrement, the peak appeared at 13 and 12 d respectively, and the peak values were (42.0 ± 3.3) x 10 4 and (29.6 ± 4.5) x 10 4 /min in muscle groups, respectively; while the peak appeared at 5 and 9 d, respectively and the peak values were (49.0 ± 10.2) x 10 4 and (28.5 ± 7.1) x 10 4 /min in liver groups, respectively. Cumulative excretion ratios in urine and excrement were 36.58% and 10.62% in muscle groups, respectively and 23.48% and 8.76% in liver groups till 30 d, respectively. The liver absorbed doses were 30.6 and 55.6 Gy in liver groups, while those were 2.3 and 6.5 Gy in muscle groups. The maximus absorbed doses of gluteus were 53.4 and 98.1 Gy in muscle groups. Conclusions: When 32 P- colloidal chromic phosphate of 794.39 MBq/m 2 was injected into the liver of Beagle, the liver absorbed dose was 56 Gy, which could be lethal dose for its strong liver toxicity and systemic side effects. Injection of 463.98-772.93 MBq/m 2 in muscle of Beagle could be safe. 32 P-colloidal chromic phosphate interstitial injection is secure to treat the solid tumors with poor and middle blood supply which could be reached by puncture. (authors)

  7. Radiation effects on cell membranes

    International Nuclear Information System (INIS)

    Koeteles, G.J.

    1982-01-01

    Experimental data are presented concerning the effects of relatively low doses of x radiation and low concentration of tritiated water (HTO) on various receptor functions - concanavalin A, cationized ferritin, poliovirus of plasma membranes of animal and human cells which point to early and temporary disturbances of the composite structures and functions of membranes. References are given to the manifold influence of radiation-induced membrane phenomenon on the development and regeneration of radiation injuries. (author)

  8. Radiation effects in optoelectronic devices

    International Nuclear Information System (INIS)

    Barnes, C.E.; Wiczer, J.J.

    1984-05-01

    Purpose of this report is to provide not only a summary of radiation damage studies at Sandia National Laboratories, but also of those in the literature on the components of optoelectronic systems: light emitting diodes (LEDs), laser diodes, photodetectors, optical fibers, and optical isolators. This review of radiation damage in optoelectronic components is structured according to device type. In each section, a brief discussion of those device properties relevant to radiation effects is given

  9. Cumulative Training Dose's Effects on Interrelationships Between Common Training-Load Models During Basketball Activity.

    Science.gov (United States)

    Scanlan, Aaron T; Fox, Jordan L; Borges, Nattai R; Dascombe, Ben J; Dalbo, Vincent J

    2017-02-01

    The influence of various factors on training-load (TL) responses in basketball has received limited attention. This study aimed to examine the temporal changes and influence of cumulative training dose on TL responses and interrelationships during basketball activity. Ten state-level Australian male junior basketball players completed 4 × 10-min standardized bouts of simulated basketball activity using a circuit-based protocol. Internal TL was quantified using the session rating of perceived exertion (sRPE), summated heart-rate zones (SHRZ), Banister training impulse (TRIMP), and Lucia TRIMP models. External TL was assessed via measurement of mean sprint and circuit speeds. Temporal TL comparisons were performed between 10-min bouts, while Pearson correlation analyses were conducted across cumulative training doses (0-10, 0-20, 0-30, and 0-40 min). sRPE TL increased (P basketball activity. sRPE TL was only significantly related to Lucia TRIMP (r = .66-.69; P basketball training doses lasting beyond 20 min. Thus, the interchangeability of commonly used internal and external TL approaches appears dose-dependent during basketball activity, with various psychophysiological mediators likely underpinning temporal changes.

  10. Effects of radiation; Effets des radiations

    Energy Technology Data Exchange (ETDEWEB)

    Masse, R [Office de Protection contre les Rayonnements Ionisants, 78 - le Vesinet (France)

    2006-07-01

    The medical consequences of a whole-body irradiation come from the destruction of cells and inflammatory reactions it provokes. The most sensitive organs are the tissues that actively split. The embryo is particularly sensitive, from 200 mSv for the effects on the brain development. The reproduction functions are reached for man from 2000 mSv, the ovary sensitivity is less, the oocytes do not split after the fetus life. For adult the bone marrow outrage leads to the disappearing of blood cells (4000 mSv). The doses from 6000 to 10000 mSv lead the failure of the digestive system and lung. for the upper doses every tissue is reached, particularly by the effects on cells of blood vessels. Important brain dysfunctions appear beyond 10000 mSv. As regards the delayed effects of overexposures the epidemiology brings to light sanitary consequences of the exposure of the population to the ionizing radiations and requires that all the possible factors associated for that purpose are considered. About hereditary effects, it appears that moderate acute radiation exposures of even a relatively large human population must have little impact, in spite of the rate of spontaneous congenital deformations is of the order of 6 %. For the induction of cancers, it is not observed excess for doses lower than 200 mSv for adults and 100 mSv for children (the populations studied are survival people of hiroshima and Nagasaki, patients treated by irradiation, uranium miners, children exposed to radioactive iodine after Chernobylsk accident). To simplify an expression of the risk has been fixed to 5% of induced cancer by Sv for population and 4% by Sv for workers, the different being explained by the demography and the sensitivity of the youngest age groups. As regards the low doses of radiations, a bundle of convergent epidemiological observations notices the absence of effects of the low doses rates. Biological mechanisms, notably of repair are approached, then certain accidents (Goiania

  11. Effects of radiation; Effets des radiations

    Energy Technology Data Exchange (ETDEWEB)

    Masse, R. [Office de Protection contre les Rayonnements Ionisants, 78 - le Vesinet (France)

    2006-07-01

    The medical consequences of a whole-body irradiation come from the destruction of cells and inflammatory reactions it provokes. The most sensitive organs are the tissues that actively split. The embryo is particularly sensitive, from 200 mSv for the effects on the brain development. The reproduction functions are reached for man from 2000 mSv, the ovary sensitivity is less, the oocytes do not split after the fetus life. For adult the bone marrow outrage leads to the disappearing of blood cells (4000 mSv). The doses from 6000 to 10000 mSv lead the failure of the digestive system and lung. for the upper doses every tissue is reached, particularly by the effects on cells of blood vessels. Important brain dysfunctions appear beyond 10000 mSv. As regards the delayed effects of overexposures the epidemiology brings to light sanitary consequences of the exposure of the population to the ionizing radiations and requires that all the possible factors associated for that purpose are considered. About hereditary effects, it appears that moderate acute radiation exposures of even a relatively large human population must have little impact, in spite of the rate of spontaneous congenital deformations is of the order of 6 %. For the induction of cancers, it is not observed excess for doses lower than 200 mSv for adults and 100 mSv for children (the populations studied are survival people of hiroshima and Nagasaki, patients treated by irradiation, uranium miners, children exposed to radioactive iodine after Chernobylsk accident). To simplify an expression of the risk has been fixed to 5% of induced cancer by Sv for population and 4% by Sv for workers, the different being explained by the demography and the sensitivity of the youngest age groups. As regards the low doses of radiations, a bundle of convergent epidemiological observations notices the absence of effects of the low doses rates. Biological mechanisms, notably of repair are approached, then certain accidents (Goiania

  12. Ionizing radiations: effects and sources

    International Nuclear Information System (INIS)

    Vignes, S.; Nenot, J.C.

    1978-01-01

    Having first mentioned the effects of ionizing radiations in cancerogenisis, pre-natal, and genetic fields, the authors present the different sources of radiations and estimate their respective contributions to the total irradiation dose. Their paper makes reference to the main elements of a report issued by the United Nations Scientific Committee in 1977 [fr

  13. Genetic effects of ionising radiation

    International Nuclear Information System (INIS)

    Saunders, P.

    1981-01-01

    The mutagenic effects of ionising radiation on germ cells with resulting genetic abnormalities in subsequent generations, are considered. Having examined a simple model to explain the interaction of ionising radiation with genetic material and discussed its limitations, the methods whereby mutations are transmitted are discussed. Methods of estimating genetic risks and the results of such studies are examined. (U.K.)

  14. Epigenetic effects of ionizing radiation

    International Nuclear Information System (INIS)

    EI-Naggar, A.M.

    2007-01-01

    Data generated during the last three decades provide evidence of Epigenetic Effects that ave-induced by ionizing radiation, particularly those of high LET values, and low level dose exposures. Epigenesist is defined as the stepwise process by which genetic information, as modified by environmental influences, is translated into the substance and behavior of cells, tissues, organism.The epigenetic effects cited in the literature are essentially classified into fine types depending on the type and nature of the effect induced.The most accepted postulation, for the occurrence of these epigenetic effects, is a radiation induced bio electric disturbances in the environment of the non-irradiated cellular volume. This will trigger signals that will induce effects in the unirradiated cells.The epigenetic effects referenced in the literature up to date are five types; namely, Genomic Instability, Bystander. Effects, Clastogenic Plasma Factors,, Abscopal Effects, and Tran generational Effects.The demonstration of Epigenetic Effects associated with exposure to ionizing radiation indicates the need to re- examine the concept of radiation dose and target size. Also an improved understanding of qualifiring and quantifying radiation risk estimates may be attained. Also, a more logical means to understand the underlying mechanisms of radiation induced carcinogenic transformation of cells

  15. Cumulative effects of wind turbines. Volume 2: Report on qualitative public attitude research in mid-Wales

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report summarises the results of research to develop a planning tool for assessing the cumulative effect of wind turbines carried out in Montgomeryshire through contact with those involved in wind farms, and those living near and further away from the wind turbine arrays. Topics examined included people's feeling about wind farms, noise, experience with wind farm developers, availability of related jobs, awareness of income to farmers from wind farms, developers' contributions to local funds, awareness of government policy, appreciation of wind as a resource, and the effects on tourism.

  16. Cumulative effects of wind turbines. Volume 2: Report on qualitative public attitude research in mid-Wales

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report summarises the results of research to develop a planning tool for assessing the cumulative effect of wind turbines carried out in Montgomeryshire through contact with those involved in wind farms, and those living near and further away from the wind turbine arrays. Topics examined included people's feeling about wind farms, noise, experience with wind farm developers, availability of related jobs, awareness of income to farmers from wind farms, developers' contributions to local funds, awareness of government policy, appreciation of wind as a resource, and the effects on tourism.

  17. Radiation hazards and biological effects of ionising radiation on man

    International Nuclear Information System (INIS)

    Siti Najila Mohd Janib

    2004-01-01

    The contents of this chapter are follows - Mechanism of damage: direct action of radiation, indirect action of radiation. Classification of effects: somatic effect, induction of cancer, factors, affecting somatic effects, genetic effect, inherited abnormalities, induced effects, early effects, late effects, deterministic effect, stochastic effect. Effect of specific group: development abnormality, childhood Cancer, fertile women, risk and uncertainty, comparison of risk

  18. Radiation and radiation effects; Strahlung und Strahlenwirkung

    Energy Technology Data Exchange (ETDEWEB)

    Neumaier, S. [Physikalisch-Technische Bundesanstalt, Berlin (Germany). Arbeitsgruppe Strahlenschutz; Janssen, H. [Physikalisch-Technische Bundesanstalt, Berlin (Germany). Abt. Ionisierende Strahlung

    2006-12-15

    The average dose incurred by the German population is about 4 millisievert p.a., about half of which results from natural radiation sources. The second half is caused nearly completely by medical applications. Only a very small fraction of the annual dose results from technical applications. This special issue of PTB focuses on the measuring problems relating to natural radiation sources and technical applications of ionizing radiation. The current contribution also outlines some important aspects of radiation exposure from medical applications. (orig.)

  19. Cumulative and antagonistic effects of a mixture of the antiandrogens vinclozolin and iprodione in the pubertal male rat.

    Science.gov (United States)

    Blystone, Chad R; Lambright, Christy S; Cardon, Mary C; Furr, Johnathan; Rider, Cynthia V; Hartig, Phillip C; Wilson, Vickie S; Gray, Leon E

    2009-09-01

    Vinclozolin and iprodione are dicarboximide fungicides that display antiandrogenic effects in the male rat, which suggests that a mixture would lead to cumulative effects on androgen-sensitive end points. Iprodione is a steroid synthesis inhibitor, but androgen receptor antagonist activity, which is displayed by vinclozolin, has not been fully evaluated. Here, we demonstrate that iprodione binds to the human androgen receptor (IC(50) = 86.0 microM), reduces androgen-dependent gene expression, and reduces androgen-sensitive tissue weights in castrated male rats (Hershberger assay). Since vinclozolin and iprodione affect common targets in the pubertal male rat, we tested the hypothesis that a mixture would have cumulative antiandrogenic effects. An iprodione dose, that does not significantly affect androgen-dependent morphological end points, was combined with vinclozolin doses (2 x 5 factorial design). Sprague-Dawley rats were dosed by gavage with vinclozolin at 0, 10, 30, 60, and 100 mg/kg/day with and without 50 mg iprodione/kg/day from postnatal day (PND) 23 to 55-57 (n = 8 per group). The age at puberty (preputial separation [PPS]), organ weights, serum hormones, and ex vivo testis steroid hormone production were measured. Vinclozolin delayed PPS, reduced androgen-sensitive organ weights, and increased serum testosterone. The addition of iprodione enhanced the vinclozolin inhibition of PPS (PND 47.5 vs.49.1; two-way ANOVA: iprodione main effect p = 0.0002). The dose response for several reproductive and nonreproductive organ weights was affected in a cumulative manner. In contrast, iprodione antagonized the vinclozolin-induced increase in serum testosterone. These results demonstrate that these fungicides interact on common targets in a tissue-specific manner when coadministered to the pubertal male rat.

  20. Dose monitoring using the DICOM structured report: assessment of the relationship between cumulative radiation exposure and BMI in abdominal CT

    International Nuclear Information System (INIS)

    Boos, J.; Lanzman, R.S.; Meineke, A.; Heusch, P.; Sawicki, L.M.; Antoch, G.; Kröpil, P.

    2015-01-01

    Aim: To perform a systematic, large-scale analysis using the Digital Imaging and Communication in Medicine structured report (DICOM-SR) to assess the relationship between body mass index (BMI) and radiation exposure in abdominal CT. Materials and methods: A retrospective analysis of DICOM-SR of 3121 abdominal CT examinations between April 2013 and March 2014 was performed. All examinations were conducted using a 128 row CT system. Patients (mean age 61 ± 15 years) were divided into five groups according to their BMI: group A <20 kg/m 2 (underweight), group B 20–25 kg/m 2 (normal weight), group C 25–30 kg/m 2 (overweight), group D 30–35 kg/m 2 (obese), and group E > 35 kg/m 2 (extremely obese). CT dose index (CTDI vol ) and dose–length product (DLP) were compared between all groups and matched to national diagnostic reference values. Results: The mean CTDI vol and DLP were 5.4 ± 2.9 mGy and 243 ± 153 mGy·cm in group A, 6 ± 3.6 mGy and 264 ± 179 mGy• cm in group B, 7 ± 3.6 mGy and 320 ± 180 mGy• cm in group C, 8.1 ± 5.2 mGy and 375 ± 306 mGy• cm in group D, and 10 ± 8 mGy and 476 ± 403 mGy• cm in group E, respectively. Except for group A versus group B, CTDI vol and DLP differed significantly between all groups (p<0.05). Significantly more CTDI vol values exceeded national diagnostic reference values in groups D and E (2.1% and 6.3%) compared to group B (0.5%, p<0.05). Conclusion: DICOM-SR is a comprehensive, fast, and reproducible way to analyse dose-related data at CT. It allows for automated evaluation of radiation dose in a large study population. Dose exposition is related to the patient's BMI and is increased by up to 96% for extremely obese patients undergoing abdominal CT. - Highlights: • DICOM-SR was used to implement automatic CT-dose monitoring. • DICOM-SR allowed for a fast and comprehensive analysis of CT dose data. • Radiation exposure for abdominal CT was increased by up to 96% for

  1. Temperature-related mortality estimates after accounting for the cumulative effects of air pollution in an urban area.

    Science.gov (United States)

    Stanišić Stojić, Svetlana; Stanišić, Nemanja; Stojić, Andreja

    2016-07-11

    To propose a new method for including the cumulative mid-term effects of air pollution in the traditional Poisson regression model and compare the temperature-related mortality risk estimates, before and after including air pollution data. The analysis comprised a total of 56,920 residents aged 65 years or older who died from circulatory and respiratory diseases in Belgrade, Serbia, and daily mean PM10, NO2, SO2 and soot concentrations obtained for the period 2009-2014. After accounting for the cumulative effects of air pollutants, the risk associated with cold temperatures was significantly lower and the overall temperature-attributable risk decreased from 8.80 to 3.00 %. Furthermore, the optimum range of temperature, within which no excess temperature-related mortality is expected to occur, was very broad, between -5 and 21 °C, which differs from the previous findings that most of the attributable deaths were associated with mild temperatures. These results suggest that, in polluted areas of developing countries, most of the mortality risk, previously attributed to cold temperatures, can be explained by the mid-term effects of air pollution. The results also showed that the estimated relative importance of PM10 was the smallest of four examined pollutant species, and thus, including PM10 data only is clearly not the most effective way to control for the effects of air pollution.

  2. Radiation effects on structural materials

    International Nuclear Information System (INIS)

    Ghoniem, N.M.

    1991-01-01

    This report discusses the following topics on the effect radiation has on thermonuclear reactor materials: Atomic Displacements; Microstructure Evolution; Materials Engineering, Mechanics, and Design; Research on Low-Activation Steels; and Research Motivated by Grant Support

  3. Biological effects of ionizing radiation

    International Nuclear Information System (INIS)

    Gisone, Pablo; Perez, Maria R.

    2001-01-01

    It has been emphasised the importance of DNA as the main target for ionizing radiation, that can induce damage by its direct action on this molecule or by an indirect effect mediated by free-radicals generated by water radiolysis. Biological effects of ionizing radiation are influenced not only by the dose but also by the dose-rate and the radiation quality. Radiation induced damage, mainly DNA single and double strand breaks, is detected by molecular sensors which in turn trigger signalling cascades leading to cell cycle arrest to allow DNA repair or programmed cell death (apoptosis). Those effects related with cell death, named deterministic, exhibits a dose-threshold below which they are not observed. Acute radiation syndrome and radiological burns are examples of this kind of effects. Other radiation induced effects, called stochastic, are the consequence of cell transformation and do not exhibit a dose-threshold. This is the case of cancer induction and hereditary effects. The aim of this presentation is briefly describe the main aspects of deterministic and stochastic effects from the point of view of radiobiology and radio pathology. (author)

  4. Effects after prenatal radiation exposures

    International Nuclear Information System (INIS)

    Streffer, C.

    2001-01-01

    The mammalian organism is highly radiosensitive during all prenatal developmental periods. For most effects a dose relationship with a threshold is observed. These threshold doses are generally above the exposures from medical diagnostic procedures. The quality and extent of radiation effects are very much dependent on the developmental stage during which an exposure takes place and on the radiation dose. An exposure during the preimplantation period will cause lethality. Malformations are usually induced after exposures during the major organogenesis. Growth retardation is also possible during the late organogenesis and foetal periods. The lower limits of threshold doses for these effects are in the range of 100 mGy. A radiation exposure during the early foetal period can lead to severe mental retardation and impairment of intelligence. There are very serious effects with radiation doses above 0.3 Gy. Carcinogenesis can apparently occur after radiation exposures during the total prenatal development period. The radiation risk factor up to now has not been clear, but it seems that it is in the range of risk factors for cancer that are observed after exposures during childhood. For radiation doses that are used in radiological diagnostics the risk is zero or very low. A termination of pregnancy after doses below 100 mGy should not be considered. (author)

  5. Effects of radiation on erythropoiesis

    Energy Technology Data Exchange (ETDEWEB)

    Harriss, E B

    1971-04-01

    Since the pioneer work of Heineke (1903; 1905) many workers have studied the effect of radiation on haemopoiesis. Their work has been reviewed by Bloom (1948), by Jacobson (1954) and more recently by Bond et al. (1965). The subject continues to stimulate much interest but is now more concerned with the effects of radiation on the multipotential stem cell pool than on radiation damage to the erythropoietic cells themselves. Death from haemopoietic failure following an LD{sub 50/30} dose of radiation is probably not attributable to failure of erythropoiesis; while damage to the erythropoietic system certainly plays a part in the syndrome, it is not a major factor contributing to the death of the animal. Although the severity and time course of the response vary with the species studied, the general effects of radiation on erythropoiesis are similar in all mammalian bone marrow studied to date. Likewise, though the severity of the reaction varies somewhat with the energy of the radiation and has been used to compare the relative biological effectiveness of different types of radiation (Sinclair et al., 1962; Sztanyik, 1967), the response is different only in degree and not in its fundamental pattern. The initial syndrome of depression and recovery will therefore be described largely by reference to work performed on the response of the rat to single acute exposures of either whole-body or partial-body irradiation with conventional X-rays.

  6. Cumulative Effects of Foraging Behavior and Social Dominance on Brain Development in a Facultatively Social Bee (Ceratina australensis).

    Science.gov (United States)

    Rehan, Sandra M; Bulova, Susan J; O'Donnell, Sean

    2015-01-01

    In social insects, both task performance (foraging) and dominance are associated with increased brain investment, particularly in the mushroom bodies. Whether and how these factors interact is unknown. Here we present data on a system where task performance and social behavior can be analyzed simultaneously: the small carpenter bee Ceratina australensis. We show that foraging and dominance have separate and combined cumulative effects on mushroom body calyx investment. Female C. australensis nest solitarily and socially in the same populations at the same time. Social colonies comprise two sisters: the social primary, which monopolizes foraging and reproduction, and the social secondary, which is neither a forager nor reproductive but rather remains at the nest as a guard. We compare the brains of solitary females that forage and reproduce but do not engage in social interactions with those of social individuals while controlling for age, reproductive status, and foraging experience. Mushroom body calyx volume was positively correlated with wing wear, a proxy for foraging experience. We also found that, although total brain volume did not vary among reproductive strategies (solitary vs. social nesters), socially dominant primaries had larger mushroom body calyx volumes (corrected for both brain and body size variation) than solitary females; socially subordinate secondaries (that are neither dominant nor foragers) had the least-developed mushroom body calyces. These data demonstrate that sociality itself does not explain mushroom body volume; however, achieving and maintaining dominance status in a group was associated with mushroom body calyx enlargement. Dominance and foraging effects were cumulative; dominant social primary foragers had larger mushroom body volumes than solitary foragers, and solitary foragers had larger mushroom body volumes than nonforaging social secondary guards. This is the first evidence for cumulative effects on brain development by

  7. Aerosol effects in radiation transfer

    International Nuclear Information System (INIS)

    Binenko, V.I.; Harshvardhan, H.

    1993-01-01

    The radiative properties and effects of aerosols are assessed for the following aerosol sources: relatively clean background aerosol, dust storms and dust outbreaks, anthropogenic pollution, and polluted cloud layers. Studies show it is the submicron aerosol fraction that plays a dominant radiative role in the atmosphere. The radiative effect of the aerosol depends not only on its loading but also on the underlying surface albedo and on solar zenith angle. It is only with highly reflecting surfaces such as Arctic ice that aerosols have a warming effect. Radiometric, microphysical, mineral composition, and refractive index measurements are presented for dust and in particular for the Saharan aerosol layer (SAL). Short-wave radiative heating of the atmosphere is caused by the SAL and is due mainly to absorption. However, the SAL does not contribute significantly to the long-wave thermal radiation budget. Field program studies of the radiative effects of aerosols are described. Anthropogenic aerosols deplete the incoming solar radiation. A case field study for a regional Ukrainian center is discussed. The urban aerosol causes a cooling of metropolitan centers, compared with outlying areas, during the day, which is followed by a warming trend at night. In another study, an increase in turbidity by a factor of 3 due to increased industrialization for Mexico City is noted, together with a drop in atmospheric transmission by 10% over a 50-year period. Numerous studies are cited that demonstrate that anthropogenic aerosols affect both the microphysical and radiative properties of clouds, which in turn affect regional climate. Particles acting as cloud nuclei are considered to have the greatest indirect effect on cloud absorptivity of short-wave radiation. Satellite observations show that low-level stratus clouds contaminated by ship exhaust at sea lead to an increase in cloud albedo

  8. Low level radiation: biological effects

    International Nuclear Information System (INIS)

    Loken, M.K.

    1983-01-01

    It is imperative that physicians and scientists using radiations in health care delivery continue to assess the benefits derived, vs. potential risk, to patients and radiation workers being exposed to radiation in its various forms as part of our health delivery system. Insofar as possible we should assure our patients and ourselves that the benefits outweigh the potential hazards involved. Inferences as to the possible biological effects of low level radiation are generally based on extrapolations from those effects observed and measured following acute exposures to considerably higher doses of radiation. Thus, in order to shed light on the question of the possible biological effects of low level radiation, a wide variety of studies have been carried out using cells in culture and various species of plant and animal life. This manuscript makes reference to some of those studies with indications as to how and why the studies were done and the conclusions that might be drawn there from. In addition reference is made to the handling of this information by scientists, by environmentalists, and by the news media. Unfortunately, in many instances the public has been misled by what has been said and/or written. It is hoped that this presentation will provide an understandable and reasonable perspective on the various appropriate uses of radiation in our lives and how such uses do provide significant improvement in our health and in our quality of life

  9. Topical Day on Biological Effects of Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Baatout, S.; Jacquet, P.

    1997-05-15

    The topical day has been focussed on the potential effects of ionizing radiation on human health. A general overview on molecular and biophysical aspects of radiation, its effects on cells and organisms, and the contribution of radiobiology to radiation protection and risk assessment is given. The genetic effects of radiation and its effects on the developing organism, the effects of radiation on the cell cycle and the mechanisms of radiation induced apoptosis were also discussed.

  10. Topical Day on Biological Effects of Radiation

    International Nuclear Information System (INIS)

    Baatout, S.; Jacquet, P.

    1997-01-01

    The topical day has been focussed on the potential effects of ionizing radiation on human health. A general overview on molecular and biophysical aspects of radiation, its effects on cells and organisms, and the contribution of radiobiology to radiation protection and risk assessment is given. The genetic effects of radiation and its effects on the developing organism, the effects of radiation on the cell cycle and the mechanisms of radiation induced apoptosis were also discussed

  11. SU-C-207A-07: Cumulative 18F-FDG Uptake Histogram Relative to Radiation Dose Volume Histogram of Lung After IMRT Or PSPT and Their Association with Radiation Pneumonitis

    International Nuclear Information System (INIS)

    Shusharina, N; Choi, N; Bortfeld, T; Liao, Z; Mohan, R

    2016-01-01

    Purpose: To determine whether the difference in cumulative 18F-FDG uptake histogram of lung treated with either IMRT or PSPT is associated with radiation pneumonitis (RP) in patients with inoperable stage II and III NSCLC. Methods: We analyzed 24 patients from a prospective randomized trial to compare IMRT (n=12) with vs. PSPT (n=12) for inoperable NSCLC. All patients underwent PET-CT imaging between 35 and 88 days post-therapy. Post-treatment PET-CT was aligned with planning 4D CT to establish a voxel-to-voxel correspondence between post-treatment PET and planning dose images. 18F-FDG uptake as a function of radiation dose to normal lung was obtained for each patient. Distribution of the standard uptake value (SUV) was analyzed using a volume histogram method. The image quantitative characteristics and DVH measures were correlated with clinical symptoms of pneumonitis. Results: Patients with RP were present in both groups: 5 in the IMRT and 6 in the PSPT. The analysis of cumulative SUV histograms showed significantly higher relative volumes of the normal lung having higher SUV uptake in the PSPT patients for both symptomatic and asymptomatic cases (VSUV=2: 10% for IMRT vs 16% for proton RT and VSUV=1: 10% for IMRT vs 23% for proton RT). In addition, the SUV histograms for symptomatic cases in PSPT patients exhibited a significantly longer tail at the highest SUV. The absolute volume of the lung receiving the dose >70 Gy was larger in the PSPT patients. Conclusion: 18F-FDG uptake – radiation dose response correlates with RP in both groups of patients by means of the linear regression slope. SUV is higher for the PSPT patients for both symptomatic and asymptomatic cases. Higher uptake after PSPT patients is explained by larger volumes of the lung receiving high radiation dose.

  12. Effects of radiation-counselling convergence education on radiation awareness

    Energy Technology Data Exchange (ETDEWEB)

    Seoung, Youl Hun [Dept. of Radiological Science, College of Health Science, Cheongju University, Cheongju (Korea, Republic of)

    2017-06-15

    The purpose of study was to analysis on the effects of radiation-counselling convergence education on radiation awareness. The survey objects were students of radiation-counselling convergence education from 12th May to 22th June in 2016. The questionnaires were education satisfactions and radiation awareness (risk, benefit, control) by Likert-type 5 scales. The analysis results revealed that education satisfactions of men students showed a significant higher female students and correlation coefficient of education satisfactions were the best high in the benefit and control of radiation. Finally radiation-counselling convergence education had a significant effect on radiation benefit. This convergence education influenced positive recognition on radiation benefit and it was indicated that radiation-counselors could treat clients on the basis of radiation benefit.

  13. Effects of radiation-counselling convergence education on radiation awareness

    International Nuclear Information System (INIS)

    Seoung, Youl Hun

    2017-01-01

    The purpose of study was to analysis on the effects of radiation-counselling convergence education on radiation awareness. The survey objects were students of radiation-counselling convergence education from 12th May to 22th June in 2016. The questionnaires were education satisfactions and radiation awareness (risk, benefit, control) by Likert-type 5 scales. The analysis results revealed that education satisfactions of men students showed a significant higher female students and correlation coefficient of education satisfactions were the best high in the benefit and control of radiation. Finally radiation-counselling convergence education had a significant effect on radiation benefit. This convergence education influenced positive recognition on radiation benefit and it was indicated that radiation-counselors could treat clients on the basis of radiation benefit

  14. Synergistic effect of cumulative corticosteroid dose and immunosuppressants on avascular necrosis in patients with systemic lupus erythematosus.

    Science.gov (United States)

    Kwon, H H; Bang, S Y; Won, S; Park, Y; Yi, J H; Joo, Y B; Lee, H S; Bae, S C

    2018-01-01

    Objectives Avascular necrosis (AVN) is one of the most common causes of organ damage in patients with systemic lupus erythematosus (SLE) and often causes serious physical disability. The aims of this study were to investigate clinical risk factors associated with symptomatic AVN and to analyze their synergistic effects in a large SLE cohort in Korea. Methods Patients with SLE were enrolled and followed from 1998 to 2014 in the Hanyang BAE Lupus cohort, and damage was measured annually according to the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI). AVN was confirmed by imaging study if patients had symptoms. To determine risk factors for AVN, clinical, laboratory and therapeutic variables were analyzed by logistic regression. Relative excess risk due to interaction (RERI), attributable proportion (AP), and synergy index (S) were calculated to measure interactions between significant variables. Results Among 1219 SLE patients, symptomatic AVN was the most common type of musculoskeletal damage (10.8%, n = 132). SLE patients with AVN showed an earlier onset age, demonstrated AVN more commonly in conjunction with certain other clinical manifestations such as renal and neuropsychiatric disorders, and received significantly higher total cumulative corticosteroid dose and immunosuppressive agents than did patients without AVN. However, in multivariable analysis, only two variables including use of a cumulative corticosteroid dose greater than 20 g (odds ratio (OR) 3.62, p = 0.015) and use of immunosuppressants including cyclophosphamide or mycophenolate mofetil (OR 4.51, p AVN. Patients with cumulative corticosteroid dose > 20 g and immunosuppressant use had a 15.44-fold increased risk for AVN, compared with patients without these risk factors ( p AVN in our Korean lupus cohort. Conclusions An individual risk assessment for AVN development should be made prior to and during treatment for SLE

  15. Salvage logging following fires can minimize boreal caribou habitat loss while maintaining forest quotas: An example of compensatory cumulative effects.

    Science.gov (United States)

    Beguin, Julien; McIntire, Eliot J B; Raulier, Frédéric

    2015-11-01

    Protected area networks are the dominant conservation approach that is used worldwide for protecting biodiversity. Conservation planning in managed forests, however, presents challenges when endangered species use old-growth forests targeted by the forest industry for timber supply. In many ecosystems, this challenge is further complicated by the occurrence of natural disturbance events that disrupt forest attributes at multiple scales. Using spatially explicit landscape simulation experiments, we gather insights into how these large scale, multifaceted processes (fire risk, timber harvesting and the amount of protected area) influenced both the persistence of the threatened boreal caribou and the level of timber supply in the boreal forest of eastern Canada. Our result showed that failure to account explicitly and a priori for fire risk in the calculation of timber supply led to an overestimation of timber harvest volume, which in turn led to rates of cumulative disturbances that threatened both the long-term persistence of boreal caribou and the sustainability of the timber supply itself. Salvage logging, however, allowed some compensatory cumulative effects. It minimised the reductions of timber supply within a range of ∼10% while reducing the negative impact of cumulative disturbances caused by fire and logging on caribou. With the global increase of the human footprint on forest ecosystems, our approach and results provide useful tools and insights for managers to resolve what often appear as lose-lose situation between the persistence of species at risk and timber harvest in other forest ecosystems. These tools contribute to bridge the gap between conservation and forest management, two disciplines that remain too often disconnected in practice. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Radiation, chemicals and combined effects

    International Nuclear Information System (INIS)

    Sinclair, W.K.

    1991-01-01

    A brief background has been provided on current carcinogenic risks from ionizing radiation and their magnitude in background circumstances. The magnitude of the risks from possibly carcinogenic chemicals at background levels in air, water and food are surprisingly similar. The exception is, perhaps, for the single source of radon which, while variable, on the average stands out above all other sources. Some basic principles concerning the interaction of combined radiation and chemicals and some practical examples where the two interact synergistically to enhance radiation effects has also been provided. Areas for human research in the future are discussed. (Author)

  17. Measuring space radiation shielding effectiveness

    OpenAIRE

    Bahadori Amir; Semones Edward; Ewert Michael; Broyan James; Walker Steven

    2017-01-01

    Passive radiation shielding is one strategy to mitigate the problem of space radiation exposure. While space vehicles are constructed largely of aluminum, polyethylene has been demonstrated to have superior shielding characteristics for both galactic cosmic rays and solar particle events due to the high hydrogen content. A method to calculate the shielding effectiveness of a material relative to reference material from Bragg peak measurements performed using energetic heavy charged particles ...

  18. Radiation effects in optical components

    International Nuclear Information System (INIS)

    Friebele, E.J.

    1987-01-01

    This report discusses components of high performance optical devices may be exposed to high energy radiation environments during their lifetime. The effect of these adverse environments depends upon a large number of parameters associated with the radiation (nature, energy, dose, dose rate, etc.) or the system (temperature, optical performance requirements, optical wavelength, optical power, path length, etc.), as well as the intrinsic susceptibility of the optical component itself to degradation

  19. Environmental dosimetry and radiation effects

    International Nuclear Information System (INIS)

    Woodhead, D.S.

    1997-01-01

    Specific assessment of the potential effects on wild organisms of increased radiation exposure arising from the authorized disposal of radioactive wastes to the environment requires two interrelated sets of information. First, an estimate is required of the incremental radiation exposure; and second, dose rate-response relationships are necessary to predict the potential impact of the estimated incremental exposure. Each of these aspects will be discussed in detail. (author)

  20. Radiation effects at the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Gilchriese, M.G.D. [ed.] [Superconducting Super Collider Lab., Dallas, TX (United States)

    1988-06-01

    This report contains a preliminary study of the effects of the radiation levels expected at the SSC on potential detector components and a subset of materials to be used in the SSC accelerators. The report does not contain a discussion of radiation damage to electronics components that may be used at the SSC. We have investigated many of the effects of radiation on silicon detectors, on wire chambers, on scintillating materials and the associated readout, on optical fibers for data transmission and on structural or other materials to be used in detector or accelerator components. In the SSC accelerator complex, in particular the storage rings, radiation damage will not present significant problems different than those now faced by existing high energy accelerators. We find that the effects of radiation damage on SSC detector components will be significant at the design luminosity of the ssc and will limit, or determine, many of the options for different detector components. In this regard the reader should keep in mind that, in the absence of a specific detector design, it is not possible to form definitive conclusions regarding the viability of the detector components. Since the radiation levels in experiments at the SSC will depend on the geometry and composition of the apparatus, simple yes /no generalizations about the feasibility of a detector component are not possible.

  1. Cumulative effects of restoration efforts on ecological characteristics of an open water area within the Upper Mississippi River

    Science.gov (United States)

    Gray, B.R.; Shi, W.; Houser, J.N.; Rogala, J.T.; Guan, Z.; Cochran-Biederman, J. L.

    2011-01-01

    Ecological restoration efforts in large rivers generally aim to ameliorate ecological effects associated with large-scale modification of those rivers. This study examined whether the effects of restoration efforts-specifically those of island construction-within a largely open water restoration area of the Upper Mississippi River (UMR) might be seen at the spatial scale of that 3476ha area. The cumulative effects of island construction, when observed over multiple years, were postulated to have made the restoration area increasingly similar to a positive reference area (a proximate area comprising contiguous backwater areas) and increasingly different from two negative reference areas. The negative reference areas represented the Mississippi River main channel in an area proximate to the restoration area and an open water area in a related Mississippi River reach that has seen relatively little restoration effort. Inferences on the effects of restoration were made by comparing constrained and unconstrained models of summer chlorophyll a (CHL), summer inorganic suspended solids (ISS) and counts of benthic mayfly larvae. Constrained models forced trends in means or in both means and sampling variances to become, over time, increasingly similar to those in the positive reference area and increasingly dissimilar to those in the negative reference areas. Trends were estimated over 12- (mayflies) or 14-year sampling periods, and were evaluated using model information criteria. Based on these methods, restoration effects were observed for CHL and mayflies while evidence in favour of restoration effects on ISS was equivocal. These findings suggest that the cumulative effects of island building at relatively large spatial scales within large rivers may be estimated using data from large-scale surveillance monitoring programs. Published in 2010 by John Wiley & Sons, Ltd.

  2. Phenomenological pictures on the cumulative effect in nucleus-nucleus collisions at the incident kinetic energy of 3.65 A GeV

    International Nuclear Information System (INIS)

    Besliu, Calin; Jipa, Alexandru; Zaharia, Radu; Tugulea, Mircea; Iosif, Maria; Argintaru, Dan; Argintaru, Cristina

    1996-01-01

    In this work new experimental results on the cumulative production of the negative pions are reported. Eight central and peripheral (inelastic) collisions at 4.5 A GeV/c incident momentum are taken into account comparisons with experimental results on the cumulative effects obtained in n-p collisions at 4.53 GeV/c and O-Ne, O-Pb collisions at 4.5 A GeV/c are included in this work. A significant cumulative production of negative pions is observed. The non-equilibrium mechanisms can be considered for cumulative effect. The experiments have been performed at the Synchrophasotron from JINR Dubna in the frame of the SKM 200 Collaboration. (authors)

  3. Modeling cumulative effects in life cycle assessment: the case of fertilizer in wheat production contributing to the global warming potential.

    Science.gov (United States)

    Laratte, Bertrand; Guillaume, Bertrand; Kim, Junbeum; Birregah, Babiga

    2014-05-15

    This paper aims at presenting a dynamic indicator for life cycle assessment (LCA) measuring cumulative impacts over time of greenhouse gas (GHG) emissions from fertilizers used for wheat cultivation and production. Our approach offers a dynamic indicator of global warming potential (GWP), one of the most used indicator of environmental impacts (e.g. in the Kyoto Protocol). For a case study, the wheat production in France was selected and considered by using data from official sources about fertilizer consumption and production of wheat. We propose to assess GWP environmental impact based on LCA method. The system boundary is limited to the fertilizer production for 1 ton of wheat produced (functional unit) from 1910 to 2010. As applied to wheat production in France, traditional LCA shows a maximum GWP impact of 500 kg CO2-eq for 1 ton of wheat production, whereas the GWP impact of wheat production over time with our approach to dynamic LCA and its cumulative effects increases to 18,000 kg CO2-eq for 1 ton of wheat production. In this paper, only one substance and one impact assessment indicator are presented. However, the methodology can be generalized and improved by using different substances and indicators. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Health effects of ionising radiation

    International Nuclear Information System (INIS)

    Mohammadi, S.

    2000-01-01

    Human and animal studies have shown an increased incidence of cancer and malformation due to radioactive materials and external radiation. The biological effects of radiation on tissues are the occurrence of morphological and functional changes in the body. The critical parts of the body are those tissues or organs which when irradiated, are likely to influence the health of the individual or its offspring. The probability of these changes depends on the radiation dose. There are two main types of damage due to radiation dose. Radiation Sickness with well-defined symptoms like cancer and inherited disorders which can appear after several years. A second type of damage, namely Acute Radiation Sickness results after exposure of the whole or parts of the body to high doses of radiation greater than 1 Gy. There are safety standards for the amount of dose equivalent that is taken as acceptable. The International Commission on Radiological Protection (ICRP) has given norms in which natural and medical causes were not included. These are given as recommended values (1966) and proposed values (2000), both in mSv/yr: population at large: 1.7 and 0.4; members of the public: 5 and 2; and radiologic workers: 50 and 20, respectively. Taking into account the increased number of reactor accidents, the question is how safe is our safety standards? Even when one is able to connect a quantitative risk with a radiation dose, there are three fundamental principles which we should obey in dealing with risks from radiation. These are: (1) Avoid any risk. (2) The risk should be related to the possible benefit. (3) Any dose below the politically agreed limits is acceptable

  5. Harmful effects of ultraviolet radiation

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    Tanning for cosmetic purposes by sunbathing or by using artificial tanning devices is widespread. The hazards associated with exposure to ultraviolet radiation are of concern to the medical profession. Depending on the amount and form of the radiation, as well as on the skin type of the individual exposed, ultraviolet radiation causes erythema, sunburn, photodamage (photoaging), photocarcinogenesis, damage to the eyes, alteration of the immune system of the skin, and chemical hypersensitivity. Skin cancers most commonly produced by ultraviolet radiation are basal and squamous cell carcinomas. There also is much circumstantial evidence that the increase in the incidence of cutaneous malignant melanoma during the past half century is related to increased sun exposure, but this has not been proved. Effective and cosmetically acceptable sunscreen preparations have been developed that can do much to prevent or reduce most harmful effects to ultraviolet radiation if they are applied properly and consistently. Other safety measures include (1) minimizing exposure to ultraviolet radiation, (2) being aware of reflective surfaces while in the sun, (3) wearing protective clothing, (4) avoiding use of artificial tanning devices, and (5) protecting infants and children

  6. Biological effects of nuclear radiation

    International Nuclear Information System (INIS)

    Hotz, G.

    1975-01-01

    After a brief survey about the main radiobiological effects caused by ionizing radiation, human symptoms after irradiation and incorporation are shown. The special radiotoxic effect of radionuclides which are chemically associated with metabolism-specific elements such as calcium and potassium is shown and methods of treatment are indicated. (ORU) [de

  7. Radiation Effects in Carbon Nanoelectronics

    Directory of Open Access Journals (Sweden)

    Cory D. Cress

    2012-07-01

    Full Text Available We experimentally investigate the effects of Co-60 irradiation on the electrical properties of single-walled carbon nanotube and graphene field-effect transistors. We observe significant differences in the radiation response of devices depending on their irradiation environment, and confirm that, under controlled conditions, standard dielectric hardening approaches are applicable to carbon nanoelectronics devices.

  8. Cumulative effects of climate and landscape change drive spatial distribution of Rocky Mountain wolverine (Gulo gulo L.).

    Science.gov (United States)

    Heim, Nicole; Fisher, Jason T; Clevenger, Anthony; Paczkowski, John; Volpe, John

    2017-11-01

    Contemporary landscapes are subject to a multitude of human-derived stressors. Effects of such stressors are increasingly realized by population declines and large-scale extirpation of taxa worldwide. Most notably, cumulative effects of climate and landscape change can limit species' local adaptation and dispersal capabilities, thereby reducing realized niche space and range extent. Resolving the cumulative effects of multiple stressors on species persistence is a pressing challenge in ecology, especially for declining species. For example, wolverines ( Gulo gulo L.) persist on only 40% of their historic North American range. While climate change has been shown to be a mechanism of range retractions, anthropogenic landscape disturbance has been recently implicated. We hypothesized these two interact to effect declines. We surveyed wolverine occurrence using camera trapping and genetic tagging at 104 sites at the wolverine range edge, spanning a 15,000 km 2 gradient of climate, topographic, anthropogenic, and biotic variables. We used occupancy and generalized linear models to disentangle the factors explaining wolverine distribution. Persistent spring snow pack-expected to decrease with climate change-was a significant predictor, but so was anthropogenic landscape change. Canid mesocarnivores, which we hypothesize are competitors supported by anthropogenic landscape change, had comparatively weaker effect. Wolverine population declines and range shifts likely result from climate change and landscape change operating in tandem. We contend that similar results are likely for many species and that research that simultaneously examines climate change, landscape change, and the biotic landscape is warranted. Ecology research and species conservation plans that address these interactions are more likely to meet their objectives.

  9. Valued ecosystem components for watershed cumulative effects: an analysis of environmental impact assessments in the South Saskatchewan River watershed, Canada.

    Science.gov (United States)

    Ball, Murray A; Noble, Bram F; Dubé, Monique G

    2013-07-01

    The accumulating effects of human development are threatening water quality and availability. In recognition of the constraints to cumulative effects assessment (CEA) under traditional environmental impact assessment (EIA), there is an emerging body of research dedicated to watershed-based cumulative effects assessment (WCEA). To advance the science of WCEA, however, a standard set of ecosystem components and indicators is required that can be used at the watershed scale, to inform effects-based understanding of cumulative change, and at the project scale, to inform regulatory-based project based impact assessment and mitigation. A major challenge, however, is that it is not clear how such ecosystem components and indicators for WCEA can or should be developed. This study examined the use of aquatic ecosystem components and indicators in EIA practice in the South Saskatchewan River watershed, Canada, to determine whether current practice at the project scale could be "scaled up" to support ecosystem component and indicator development for WCEA. The hierarchy of assessment components and indicators used in a sample of 35 environmental impact assessments was examined and the factors affecting aquatic ecosystem component selection and indicator use were identified. Results showed that public environmental impact statements are not necessarily publically accessible, thus limiting opportunities for data and information sharing from the project to the watershed scale. We also found no consistent terminology across the sample of impact statements, thus making comparison of assessment processes and results difficult. Regulatory compliance was found to be the dominant factor influencing the selection of ecosystem components and indicators for use in project assessment, rather than scientific reasoning, followed by the mandate of the responsible government agency for the assessment, public input to the assessment process, and preexisting water licensing arrangements external

  10. A comparison of alternative methods of calculating complementary cumulative distribution functions of health effects following an atmospheric radioactive release

    International Nuclear Information System (INIS)

    Ponting, A.C.; Nair, S.

    1984-04-01

    A concept extensively used in studying the consequences of accidental atmospheric radioactive releases is that of the Complementary Cumulative Distribution Function, CCDF. Various methods of calculating CCDFs have been developed with particular applications in putting degraded core accidents in perspective and in identifying release sequences leading to high risks. This note compares three methods with specific reference to their accuracy and computational efficiency. For two of the methods (that used in the US Reactor Safety Study code CRAC2 and extended version of that method), the effects of varying the sector width and considering site-specific population distributions have been determined. For the third method it is only necessary to consider the effects of site-specific population distributions. (author)

  11. Kinetic theory of radiation effects

    International Nuclear Information System (INIS)

    Mansur, L.K.

    1987-01-01

    To help achieve the quantitative and mechanistic understanding of these processes, the kinetic theory of radiation effects has been developed in the DOE basic energy sciences radiation effects and fusion reactor materials programs, as well as in corresponding efforts in other countries. This discipline grapples with a very wide range of phenomena and draws on numerous sub-fields of theory such as defect physics, diffusion, elasticity, chemical reaction rates, phase transformations and thermodynamics. The theory is cast in a mathematical framework of continuum dynamics. Issues particularly relevant to the present inquiry can be viewed from the standpoints of applications of the theory and areas requiring further progress

  12. Radiation research contracts: Biological effects of small radiation doses

    Energy Technology Data Exchange (ETDEWEB)

    Hug, O [International Atomic Energy Agency, Division of Health, Safety and Waste Disposal, Vienna (Austria)

    1959-04-15

    To establish the maximum permissible radiation doses for occupational and other kinds of radiation exposure, it is necessary to know those biological effects which can be produced by very small radiation doses. This particular field of radiation biology has not yet been sufficiently explored. This holds true for possible delayed damage after occupational radiation exposure over a period of many years as well as for acute reactions of the organism to single low level exposures. We know that irradiation of less than 25 Roentgen units (r) is unlikely to produce symptoms of radiation sickness. We have, however, found indications that even smaller doses may produce certain instantaneous reactions which must not be neglected

  13. The effects and control of radiation

    International Nuclear Information System (INIS)

    Saunders, P.A.H.

    1982-12-01

    The subject is discussed under the headings: introduction; ionising radiation (alpha and beta particles, gamma- and X-radiation, neutrons, half-life, sources of radiation); biological effects; risk estimates (somatic) (early effects, delayed effects); risk estimates (hereditary); control of radiation; risk estimates (accidents). (U.K.)

  14. Effects of cumulative trauma load on perceptions of health, blood pressure, and resting heart rate in urban African American youth.

    Science.gov (United States)

    Conner-Warren, Rhonda

    2014-04-01

    This study examined relationships between cumulative trauma (CT) and urban African American (AA) adolescents' blood pressure (BP), heart rate (HR), and perceptions of health. A correlational design using secondary data analysis studied effects of CT, health outcomes, and perceptions of health. Participants were 175 urban AA youth (11-16 years) who completed structured surveys and physiological measures of HR and BP before and after exercise. AA youth were experiencing high levels of CT. Negative correlations were obtained between AA females' perceptions of their health and systolic BP with levels of trauma. No gender differences were found in HR or BP. AA females with high CT may perceive themselves as less healthy and can be at risk for health problems. © 2014, Wiley Periodicals, Inc.

  15. Cumulative exposure to disadvantage and the intergenerational transmission of neighbourhood effects

    OpenAIRE

    Hedman, L.; Manley, D.; Van Ham, M.; Östh, J.

    2012-01-01

    Studies of neighbourhood effects typically investigate the instantaneous effect of point-in-time measures of neighbourhood poverty on individual outcomes. It has been suggested that it is not solely the current neighbourhood, but also the neigh-bourhood history of an individual that is important in determining an individual’s outcomes. The effect of long-term exposure to poverty neighbourhoods on adults has largely been ignored in the empirical literature, partly due to a lack of suitable dat...

  16. Stimulating effects of ionizing radiation

    International Nuclear Information System (INIS)

    Jaworowski, Z.

    1995-01-01

    The influence of low doses on human organism is not definite known up to now. The worldwide discussion on this topic has been presented. A lot of analysed statistical data proved that the stimulating effect of low doses of ionizing radiation really exists and can have a beneficial influence on human health. 43 refs, 4 figs, 6 tabs

  17. Radiation effects on video imagers

    International Nuclear Information System (INIS)

    Yates, G.J.; Bujnosek, J.J.; Jaramillo, S.A.; Walton, R.B.; Martinez, T.M.; Black, J.P.

    1985-01-01

    Radiation sensitivity of several photoconductive, photoemissive, and solid state silicon-based video imagers was measured by analyzing stored photocharge induced by irradiation with continuous and pulsed sources of high energy photons and neutrons. Transient effects as functions of absorbed dose, dose rate, fluences, and ionizing particle energy are presented

  18. Biopositive Effects of Ionizing Radiation?

    International Nuclear Information System (INIS)

    Broda, E.

    1972-01-01

    This paper was written for a talk given by E. Broda in Vienna for an event organised by the chemical physical society, the Austrian biochemical society and the Austrian biophysical society in December 1972. In this paper Broda analyses the question of biopositive effects of ionizing radiation. (nowak)

  19. 32 CFR 651.16 - Cumulative impacts.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Cumulative impacts. 651.16 Section 651.16... § 651.16 Cumulative impacts. (a) NEPA analyses must assess cumulative effects, which are the impact on the environment resulting from the incremental impact of the action when added to other past, present...

  20. Cumulative exposure to disadvantage and the intergenerational transmission of neighbourhood effects

    NARCIS (Netherlands)

    Hedman, L.; Manley, D.; Van Ham, M.; Östh, J.

    2012-01-01

    Studies of neighbourhood effects typically investigate the instantaneous effect of point-in-time measures of neighbourhood poverty on individual outcomes. It has been suggested that it is not solely the current neighbourhood, but also the neigh-bourhood history of an individual that is important in

  1. Modification of radiation effects

    International Nuclear Information System (INIS)

    Lindenbaum, A.

    1975-01-01

    Results are reported from studies on the tissue distribution of 239 Pu and 241 Am in mice and beagle dogs and the effectiveness of various therapeutic treatments for decorporation. In dogs injected with monomeric Pu the value of a regimen of early and prolonged treatment with DTPA (diethylenetriaminepentaacetic acid) for minimizing the Pu burden in the soft tissues and skeleton was demonstrated. These results have immediate implication for DTPA treatment in man. New studies in mice verified the action of pyran copolymer antiviral agents in enhancing the effectiveness of DTPA for removal of polymeric Pu from the liver. Recent application of autoradiographic procedures for quantitatively comparing short- and long-term localization of monomeric and polymeric 239 Pu in dog liver showed that there is no net translocation of monomeric Pu within the liver between 6 and 90 days following injection. One of the molecular studies presently underway aims at synthesis of a variety of DTPA esters. The diethyl ester has already been prepared and tested for toxicity in mice. These compounds are designed to bring DTPA into contact with plutonium deposits unavailable to the action of ionic DTPA. (U.S.)

  2. Radiation effects on eye components

    Science.gov (United States)

    Durchschlag, H.; Fochler, C.; Abraham, K.; Kulawik, B.

    1999-08-01

    The most important water-soluble components of the vertebrate eye (lens proteins, aqueous humor, vitreous, hyaluronic acid, ascorbic acid) have been investigated in aqueous solution, after preceding X- or UV-irradiation. Spectroscopic, chromatographic, electrophoretic, hydrodynamic and analytic techniques have been applied, to monitor several radiation damages such as destruction of aromatic and sulfur-containing amino acids, aggregation, crosslinking, dissociation, fragmentation, and partial unfolding. Various substances were found which were able to protect eye components effectively against radiation, some of them being also of medical relevance.

  3. Radiation Effects in Paediatric radiography

    International Nuclear Information System (INIS)

    Mutwasi, O.

    2006-01-01

    Diagnostic imaging has evolved from single technique to a field which we have a choice from many modalities. Some without radiation. Radiation producing modalities include plain films (low dose), Fluoroscopy (mid range dose), Computed tomography (high dose). Radiography dose can significantly be influenced in plain radiography by varying speed of screens, cassette construction and type of radiography. E.g. digital or computed. In computed or digital radiography we are no longer able to tell h igh dose b y the quality of images. The final image is by great extend a product of post processing algorithms. It's for this reasons that the basic understanding of the sensitivity and specifying of various types of examinations and of specifically radiation effects is mandatory for a paediatric imager

  4. Childhood Violence Exposure: Cumulative and Specific Effects on Adult Mental Health

    OpenAIRE

    Hooven, Carole; Nurius, Paula S.; Logan-Greene, Patricia; Thompson, Elaine A.

    2012-01-01

    Childhood exposure to violence and victimization is a significant public health problem, with potentially long-lasting, deleterious effects on adult mental health. Using a longitudinal study design, 123 young adults—identified in adolescence as at-risk for high school dropout—were examined for the effects of multi-domain childhood victimization on emotional distress and suicide risk, net of adolescent risk and protective factors, including family dysfunction. The hypothesis that higher levels...

  5. Measuring space radiation shielding effectiveness

    Directory of Open Access Journals (Sweden)

    Bahadori Amir

    2017-01-01

    Full Text Available Passive radiation shielding is one strategy to mitigate the problem of space radiation exposure. While space vehicles are constructed largely of aluminum, polyethylene has been demonstrated to have superior shielding characteristics for both galactic cosmic rays and solar particle events due to the high hydrogen content. A method to calculate the shielding effectiveness of a material relative to reference material from Bragg peak measurements performed using energetic heavy charged particles is described. Using accelerated alpha particles at the National Aeronautics and Space Administration Space Radiation Laboratory at Brookhaven National Laboratory, the method is applied to sample tiles from the Heat Melt Compactor, which were created by melting material from a simulated astronaut waste stream, consisting of materials such as trash and unconsumed food. The shielding effectiveness calculated from measurements of the Heat Melt Compactor sample tiles is about 10% less than the shielding effectiveness of polyethylene. Shielding material produced from the astronaut waste stream in the form of Heat Melt Compactor tiles is therefore found to be an attractive solution for protection against space radiation.

  6. Measuring space radiation shielding effectiveness

    Science.gov (United States)

    Bahadori, Amir; Semones, Edward; Ewert, Michael; Broyan, James; Walker, Steven

    2017-09-01

    Passive radiation shielding is one strategy to mitigate the problem of space radiation exposure. While space vehicles are constructed largely of aluminum, polyethylene has been demonstrated to have superior shielding characteristics for both galactic cosmic rays and solar particle events due to the high hydrogen content. A method to calculate the shielding effectiveness of a material relative to reference material from Bragg peak measurements performed using energetic heavy charged particles is described. Using accelerated alpha particles at the National Aeronautics and Space Administration Space Radiation Laboratory at Brookhaven National Laboratory, the method is applied to sample tiles from the Heat Melt Compactor, which were created by melting material from a simulated astronaut waste stream, consisting of materials such as trash and unconsumed food. The shielding effectiveness calculated from measurements of the Heat Melt Compactor sample tiles is about 10% less than the shielding effectiveness of polyethylene. Shielding material produced from the astronaut waste stream in the form of Heat Melt Compactor tiles is therefore found to be an attractive solution for protection against space radiation.

  7. Biological radiation effects

    International Nuclear Information System (INIS)

    Russo, A.

    2000-01-01

    Everyone is exposed to a complex mix of electromagnetic fields (EMF) of different frequencies that permeate our environment. Exposures to these EMF are increasing significantly as technology advances unabated and new applications are found. Technological progress in the broadest sense of the word has always been associated with various hazards and risks, both perceived and real. The industrial, commercial and household application on EMF is no exception. Throughout the world, the general public is concerned that exposure to EMF from such sources as high voltage power lines, broadcasting networks, mobile telephones and their base stations could lead to adverse health consequences, especially in children. As a result, the construction of new power lines and broadcasting and mobile telephone network has met with considerable opposition in many countries. Public exposure to EMF is regulated by a variety of voluntary and legal limits, together with various national safety standards. Guidelines are designed to avoid all identified hazards, from short and long term exposure, recommended limits. The aim of this paper is to report the summary of the actual scientific knowledge about the potential health effects and hazards due to man made EMF and the new tendencies of the social and political choices [it

  8. Clinical significance of cumulative biological effective dose and overall treatment time in the treatment of carcinoma cervix

    Directory of Open Access Journals (Sweden)

    Mandal Abhijit

    2007-01-01

    Full Text Available The purpose of this retrospective study is to report the radiotherapy treatment response of, and complications in, patients with cervical cancer on the basis of cumulative biologic effective dose (BED and overall treatment time (OTT. Sixty-four (stage II - 35/64; stage III - 29/64 patients of cervical cancer were treated with combination of external beam radiotherapy (EBRT and low dose rate intracavitary brachytherapy (ICBT. The cumulative BED was calculated at Point A (BED 10 ; and bladder, rectal reference points (BED 2.5 using the linear-quadratic BED equations. The local control (LC rate and 5-year disease-free survival (DFS rate in patients of stage II were comparable for BED 10 < 84.5 and BED 10 > 84.5 but were much higher for BED 10 > 84.5 than BED 10 < 84.5 ( P < 0.01 in stage III patients. In the stage II patients, The LC rate and 5-year DFS rate were comparable for OTT < 50 days and for OTT> 50 days but were much higher in stage III patients with OTT < 50 than OTT> 50 days ( P < 0.001. It was also observed that patients who received BED 2.5 < 105 had lesser rectal ( P < 0.001 and bladder complications than BED 2.5 > 105. Higher rectal complication-free survival (CFS R rate, bladder complication-free survival (CFS B rate and all-type late complication-free survival rate were observed in patients who received BED 2.5 < 105 than BED 2.5 > 105. A balanced, optimal and justified radiotherapy treatment schedule to deliver higher BED 10 (>84.5 and lower BED 2.5 (< 105 in lesser OTT (< 50 days is essential in carcinoma cervix to expect a better treatment outcome in all respects.

  9. Adaptive strategies for cumulative cultural learning.

    Science.gov (United States)

    Ehn, Micael; Laland, Kevin

    2012-05-21

    The demographic and ecological success of our species is frequently attributed to our capacity for cumulative culture. However, it is not yet known how humans combine social and asocial learning to generate effective strategies for learning in a cumulative cultural context. Here we explore how cumulative culture influences the relative merits of various pure and conditional learning strategies, including pure asocial and social learning, critical social learning, conditional social learning and individual refiner strategies. We replicate the Rogers' paradox in the cumulative setting. However, our analysis suggests that strategies that resolved Rogers' paradox in a non-cumulative setting may not necessarily evolve in a cumulative setting, thus different strategies will optimize cumulative and non-cumulative cultural learning. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Stigmatized biologies: Examining the cumulative effects of oral health disparities for Mexican American farmworker children.

    Science.gov (United States)

    Horton, Sarah; Barker, Judith C

    2010-06-01

    Severe early childhood caries (ECC) can leave lasting effects on children's physical development, including malformed oral arches and crooked permanent dentition. This article examines the way that the ECC of Mexican American farmworker children in the United States sets them up for lasting dental problems and social stigma as young adults. We examine the role of dietary and environmental factors in contributing to what we call "stigmatized biologies," and that of market-based dental public health insurance systems in cementing their enduring effects. We adapt Margaret Lock's term, local biology, to illustrate the way that biology differs not only because of culture, diet, and environment but also because of disparities in insurance coverage. By showing the long-term effects of ECC and disparate dental treatment on farmworker adults, we show how the interaction of immigrant caregiving practices and underinsurance can having lasting social effects. An examination of the long-term effects of farmworker children's ECC illustrates the ways that market-based health care systems can create embodied differences that in turn reproduce a system of social inequality.

  11. The cumulative effect of deuterium depleted water and pesticides used in fruit trees

    International Nuclear Information System (INIS)

    Cinca, Lidia; Butnaru, Gallia; Titescu, Gh.

    2007-01-01

    Full text: The molds as well as Monillia laxa damages on fruit trees represents 10 - 45% of the harmful agents affecting the trees. The pest utilization at a rate of 3 to 10 times will entail both a strong environment polluting effect and a fruit / food contamination. In our work we wanted to reveal the Deuterium Depleted Water (DDW) effect in enhancing the pest efficiency or to replace it at all. our results pointed out a significant increase of pest efficiency when DDW replaced neutral CuSO 4 at the first treatment. The DDW treatment (3 times) showed a similar effect as pest treatment (first - 20% neutral CuSO 4 ; second - 50% All Cupral and third 0.1% Carbendazin). The fruit yield was 44 and 42 kg/tree at the DDW and classical pest treatment, respectively. In conclusion, the difference was of no significance. (authors)

  12. The more you play, the more aggressive you become: A long-term experimental study of cumulative violent video game effects on hostile expectations and aggressive behavior

    NARCIS (Netherlands)

    Hasan, Y.; Bègue, L.; Scharkow, M.; Bushman, B.J.

    2012-01-01

    It is well established that violent video games increase aggression. There is a stronger evidence of short-term violent video game effects than of long-term effects. The present experiment tests the cumulative long-term effects of violent video games on hostile expectations and aggressive behavior

  13. Instrumental variables estimation of exposure effects on a time-to-event endpoint using structural cumulative survival models.

    Science.gov (United States)

    Martinussen, Torben; Vansteelandt, Stijn; Tchetgen Tchetgen, Eric J; Zucker, David M

    2017-12-01

    The use of instrumental variables for estimating the effect of an exposure on an outcome is popular in econometrics, and increasingly so in epidemiology. This increasing popularity may be attributed to the natural occurrence of instrumental variables in observational studies that incorporate elements of randomization, either by design or by nature (e.g., random inheritance of genes). Instrumental variables estimation of exposure effects is well established for continuous outcomes and to some extent for binary outcomes. It is, however, largely lacking for time-to-event outcomes because of complications due to censoring and survivorship bias. In this article, we make a novel proposal under a class of structural cumulative survival models which parameterize time-varying effects of a point exposure directly on the scale of the survival function; these models are essentially equivalent with a semi-parametric variant of the instrumental variables additive hazards model. We propose a class of recursive instrumental variable estimators for these exposure effects, and derive their large sample properties along with inferential tools. We examine the performance of the proposed method in simulation studies and illustrate it in a Mendelian randomization study to evaluate the effect of diabetes on mortality using data from the Health and Retirement Study. We further use the proposed method to investigate potential benefit from breast cancer screening on subsequent breast cancer mortality based on the HIP-study. © 2017, The International Biometric Society.

  14. Cumulative effect of zinc oxide and titanium oxide nanoparticles on growth and chlorophyll a content of Picochlorum sp.

    Science.gov (United States)

    Hazeem, Layla J; Bououdina, Mohammed; Rashdan, Suad; Brunet, Loïc; Slomianny, Christian; Boukherroub, Rabah

    2016-02-01

    The use of nanoparticles (NPs) is of increasing significance due to their large potential for various applications. Great attention should be paid on the possible impacts of nanoparticles on the environment as large amounts of them may reach the environment by accident or voluntarily. Marine algae are potential organisms for usage in nanopollution bioremediation in aquatic system, because of their ability to adapt to long exposure to NPs. Thus, it is of prime importance to study the possible interactions of different NPs with microalgae in assessing their potential environmental risks. Most studies on potential environmental effects of ZnO and TiO2 NPs have been performed independently and following the widely accepted, standardized test systems, which had been developed for the characterization of chemicals. In this study, we have examined the cumulative effect of ZnO and TiO2 NPs on Picochlorum sp. in addition to the individual effects of these NPs over 32 days. Our results indicate that the toxicity and availability of NPs to marine algae are reduced by their aggregation and sedimentation. NPs are found to have a negative effect on algal growth and chlorophyll a concentration during the early growth stages. In contrast, the case is reversed during the late growth stages. There is no significant difference between the effect of the NPs when they are used separately and when both ZnO and TiO2 are used together in the test (P > 0.05).

  15. Cumulative effects of white clover residues on the changes in soil ...

    African Journals Online (AJOL)

    White clover grows naturally all over the Himalayan regions including the hilly areas of the state of Azad Jammu and Kashmir (AJK), Pakistan. This study was conducted to investigate the effects of white clover residues alone or in combination with phosphorus (P) fertilizer on maize (Zea mays L.) yield, nutrient uptake and ...

  16. Cumulative effects of white clover residues on the changes in soil ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-05-18

    May 18, 2009 ... The residual effects of white clover on soil properties indicated a significant increase in saturation percentage (17–23%) and .... determined by leaching the soil with KCl followed by extraction of ...... accumulation, and oil quality of French basil. ... of the Final Workshop of the Farming System Integrated Pest.

  17. Cumulative effects of logging road sediment on salmonid populations in the Clearwater River, Jefferson County, Washington

    Science.gov (United States)

    C. J. Cederholm; L. M. Reid; E. O. Salo

    1981-01-01

    Abstract - The nature of sediment production from logging roads and the effect of the resulting sediment on salmonid spawning success in the Clearwater River drainage have been studied for eight years. The study includes intensive and extensive analyses of field situations, supplemented by several controlled experiments. It was found that significant amounts (15-25...

  18. Relationships between fathers and adult children: The cumulative effects of divorce and repartnering

    NARCIS (Netherlands)

    Kalmijn, M.

    2015-01-01

    New data from a national Dutch survey are used to examine the effects of divorce and repartnering on the relationships that fathers have with their adult children. Compared with divorced fathers who live alone, repartnered fathers have less frequent contact with their children, they exchange less

  19. Relationships between fathers and adult children: the cumulative effects of divorce and repartnering

    NARCIS (Netherlands)

    Kalmijn, M.

    2015-01-01

    New data from a national Dutch survey are used to examine the effects of divorce and repartnering on the relationships that fathers have with their adult children. Compared with divorced fathers who live alone, repartnered fathers have less frequent contact with their children, they exchange less

  20. Cumulative Repetition Effects across Multiple Readings of a Word: Evidence from Eye Movements

    Science.gov (United States)

    Kamienkowski, Juan E.; Carbajal, M. Julia; Bianchi, Bruno; Sigman, Mariano; Shalom, Diego E.

    2018-01-01

    When a word is read more than once, reading time generally decreases in the successive occurrences. This Repetition Effect has been used to study word encoding and memory processes in a variety of experimental measures. We studied naturally occurring repetitions of words within normal texts (stories of around 3,000 words). Using linear mixed…

  1. Genomic instability and radiation effects

    International Nuclear Information System (INIS)

    Christian Streffer

    2007-01-01

    Complete text of publication follows. Cancer, genetic mutations and developmental abnormalities are apparently associated with an increased genomic instability. Such phenomena have been frequently shown in human cancer cells in vitro and in situ. It is also well-known that individuals with a genetic predisposition for cancer proneness, such as ataxia telangiectesia, Fanconi anaemia etc. demonstrate a general high genomic instability e.g. in peripheral lymphocytes before a cancer has developed. Analogous data have been found in mice which develop a specific congenital malformation which has a genetic background. Under these aspects it is of high interest that ionising radiation can increase the genomic instability of mammalian cells after exposures in vitro an in vivo. This phenomenon is expressed 20 to 40 cell cycles after the exposure e.g. by de novo chromosomal aberrations. Such effects have been observed with high and low LET radiation, high LET radiation is more efficient. With low LET radiation a good dose response is observed in the dose range 0.2 to 2.0 Gy, Recently it has been reported that senescence and genomic instability was induced in human fibroblasts after 1 mGy carbon ions (1 in 18 cells are hit), apparently bystander effects also occurred under these conditions. The instability has been shown with DNA damage, chromosomal aberrations, gene mutation and cell death. It is also transferred to the next generation of mice with respect to gene mutations, chromosomal aberrations and congenital malformations. Several mechanisms have been discussed. The involvement of telomeres has gained interest. Genomic instability seems to be induced by a general lesion to the whole genome. The transmission of one chromosome from an irradiated cell to an non-irradiated cell leads to genomic instability in the untreated cells. Genomic instability increases mutation rates in the affected cells in general. As radiation late effects (cancer, gene mutations and congenital

  2. Notes on radiation effects on materials

    International Nuclear Information System (INIS)

    Anno, J.N.

    1984-01-01

    The effects of radiation from nuclear reactions on various classes of materials are examined in an introductory textbook for students of nuclear engineering. Topics discussed include the units and general scale of radiation damage, fundamental interactions of neutrons and gamma rays with materials, transient radiation effects on electrical components, radiation effects on organic materials and on steels, nuclear fission effects, surface effects of nuclear radiations, radiation effects on biological material, and neutron and gamma-ray dosimetry. Graphs, diagrams, tables of numerical data, and problems for each chapter are provided. 122 references

  3. Thermal effects in radiation processing

    International Nuclear Information System (INIS)

    Zagorski, Z.P.

    1985-01-01

    The balance of ionizing radiation energy incident on an object being processed is discussed in terms of energy losses, influencing the amount really absorbed. To obtain the amount of heat produced, the absorbed energy is corrected for the change in internal energy of the system and for the heat effect of secondary reactions developing after the initiation. The temperature of a processed object results from the heat evolved and from the specific heat of the material comprising the object. The csub(p) of most materials is usually much lower than that of aqueous systems and therefore temperatures after irradiation are higher. The role of low specific heat in radiation processing at cryogenic conditions is stressed. Adiabatic conditions of accelerator irradiation are contrasted with the steady state thermal conditions prevailing in large gamma sources. Among specific questions discussed in the last part of the paper are: intermediate and final temperature of composite materials, measurement of real thermal effects in situ, neutralization of undesired warming experienced during radiation processing, processing at temperatures other than ambient and administration of very high doses of radiation. (author)

  4. Radiation effects in silicate glasses

    International Nuclear Information System (INIS)

    Bibler, N.E.; Howitt, D.G.

    1988-01-01

    The study of radiation effects in complex silicate glasses has received renewed attention because of their use in special applications such as high level nuclear waste immobilization and fiber optics. Radiation changes the properties of these glasses by altering their electronic and atomic configurations. These alterations or defects may cause dilatations or microscopic phase changes along with absorption centers that limit the optical application of the glasses. Atomic displacements induced in the already disordered structure of the glasses may affect their use where heavy irradiating particles such as alpha particles, alpha recoils, fission fragments, or accelerated ions are present. Large changes (up to 1%) in density may result. In some cases the radiation damage may be severe enough to affect the durability of the glass in aqueous solutions. In the paper, the authors review the literature concerning radiation effects on density, durability, stored energy, microstructure and optical properties of silicate glasses. Both simple glasses and complex glasses used for immobilization of nuclear waste are considered

  5. Thermal effects in radiation processing

    International Nuclear Information System (INIS)

    Zagorski, Z.P.

    1984-01-01

    The balance of ionizing radiation energy incident on an object being processed is discussed in terms of energy losses, influencing the amount really absorbed. To obtain the amount of heat produced, the absorbed energy is corrected for the change in internal energy of the system and for the heat effect of secondary reactions developing after the initiation. The temperature of a processed object results from the heat evolved and from the specific heat of the material comprising the object. The specific heat of most materials is usually much lower than that of aqueous systems and therefore temperatures after irradiation are higher. The role of low specific heat in radiation processing at cryogenic conditions is stressed. Adiabatic conditions of accelerator irradiation are contrasted with the steady state thermal conditions prevailing in large gamma sources. Among specific questions discussed in the last part of the paper are: intermediate and final temperature of composite materials, measurement of real thermal effects in situ, neutralization of undesired warming experienced during radiation processing, processing at temperatures other than ambient and administration of very high doses of radiation

  6. Stigmatized Biologies: Examining the Cumulative Effects of Oral Health Disparities for Mexican American Farmworker Children

    OpenAIRE

    Horton, Sarah; Barker, Judith C.

    2010-01-01

    Severe early childhood caries (ECC) can leave lasting effects on children’s physical development, including malformed oral arches and crooked permanent dentition. This article examines the way that ECC sets up Mexican American farm worker children in the United States for lasting dental problems and social stigma as young adults. We examine the role of dietary and environmental factors in contributing to what we call “stigmatized biologies,” and that of market-based dental public health insur...

  7. Forecasting the Relative and Cumulative Effects of Multiple Stressors on At-risk Populations

    Science.gov (United States)

    2011-08-01

    applied to model populations of Ord’s kangaroo rat, Spotted Owls, and elk. Although the model was recently demonstrated to members of the DoD...C. C. Peterson, I. R. Wallis, K. H. Berry, and K. A. Nagy. 1998. Effects of climatic variation on field metabolism and water relations of desert...simulation experiment with endangered kangaroo rats. International Association for Landscape Ecology Annual Meeting, April 2009. A. 2 A. 3

  8. Restoring fish ecological quality in estuaries: Implication of interactive and cumulative effects among anthropogenic stressors.

    Science.gov (United States)

    Teichert, Nils; Borja, Angel; Chust, Guillem; Uriarte, Ainhize; Lepage, Mario

    2016-01-15

    Estuaries are subjected to multiple anthropogenic stressors, which have additive, antagonistic or synergistic effects. Current challenges include the use of large databases of biological monitoring surveys (e.g. the European Water Framework Directive) to help environmental managers prioritizing restoration measures. This study investigated the impact of nine stressor categories on the fish ecological status derived from 90 estuaries of the North East Atlantic countries. We used a random forest model to: 1) detect the dominant stressors and their non-linear effects; 2) evaluate the ecological benefits expected from reducing pressure from stressors; and 3) investigate the interactions among stressors. Results showed that largest restoration benefits were expected when mitigating water pollution and oxygen depletion. Non-additive effects represented half of pairwise interactions among stressors, and antagonisms were the most common. Dredged sediments, flow changes and oxygen depletion were predominantly implicated in non-additive interactions, whereas the remainder stressors often showed additive impacts. The prevalence of interactive impacts reflects a complex scenario for estuaries management; hence, we proposed a step-by-step restoration scheme focusing on the mitigation of stressors providing the maximum of restoration benefits under a multi-stress context. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Health effects of radiation and the implications for radiation safety

    International Nuclear Information System (INIS)

    Gonzalez, A.J.; Anderer, J.

    1991-01-01

    In this Paper two elements of a multiphase analysis of radiation exposures in the living environment - the human health effects of ionizing radiation and the implications for radiation safety policy and practices - are presented. Part 1 draws together the current state of scientific knowledge and insight about the human health effects of radiation, describing these in terms of known cause-related deterministic effects and of the estimated incidence of stochastic effects as defined by biostatistics and biological models. The 1988 UNSCEAR report provides an authoritative basis for such an examination. Part 2 explores some of the major implications that the state-of-the-art of radiation biology has - or should have - for radiation safety policy and practices. (author)

  10. Research on radiation effect and radiation protection at JAEA

    International Nuclear Information System (INIS)

    Saito, Kimiaki

    2007-01-01

    Researches on radiation effect and radiation protection at JAEA have been carried out in different sections. In recent years, the organizations were rearranged to attain better research circumstances, and new research programs started. At present, radiation effect studies focus on radiation effect mechanisms at atomic, molecular and cellular levels including simulation studies, and protection studies focus on dosimetry for conditions difficult to cover with currently used methods and data as well as the related basic studies. The outlines of the whole studies and also some descriptions on selected subjects will be given in this paper. (author)

  11. Early life adversity potentiates the effects of later life stress on cumulative physiological dysregulation

    DEFF Research Database (Denmark)

    Dich, Nadya; Hansen, Åse Marie; Avlund, Kirsten

    2015-01-01

    tested this hypothesis by investigating whether experience of stressful events and circumstances (SEC) in childhood or adolescence amplified the effect of adulthood SEC on physiological dysregulation (allostatic load, AL) in later midlife. Design: Observational data were used in the present study....... Physiological functioning was measured in later midlife (participants' age ranged from 49 to 63). Both childhood/adolescence and adulthood SEC were reported retrospectively on the same occasion. Methods: Participants were 5,309 Danish men and women from Copenhagen Ageing and Midlife Biobank. SEC included socio......: The results provide further insight into the mechanisms behind the "biological embedding" of childhood stress....

  12. Overexploitation and cumulative drought trend effect on Ras El Ain karstic spring discharge (Khabour Sub-basin, Syria)

    Science.gov (United States)

    Abou Zakhem, Boulos; Kattaa, Bassam

    2017-10-01

    The effects of climate change and overexploitation are being strongly perceived in the studied area and the springs discharge is obviously affected. In this paper, Ras El Ain spring discharge and precipitation were analyzed by normalized methods on an yearly timescale. The deficit of Ras El Ain spring discharge due to overexploitation factors and drought effects was estimated. Cumulative drought analyses were carried out using SPI10 and SQI10. Finally, the decreasing trends of the spring discharge due to the deficiency in rainfall were analyzed. The main results reveal that the annual mean deficit of Ras El Ain spring discharge due to overpumping was between 32 and 45%, whereas, annual mean deficit related to drought was between 22 and 35% on average, during the last 30 years (post-1984). The moving averages of SPI and SQI delineate very well the drought periods during last three decades. The cumulative droughts using SPI10 and SQI10 reveal that wet period (pre-1984) with positive values was characterized by high precipitation and spring discharge. Overexploitation period (1984-1989) is distinguished by decreasing SQI10 values whereas, SPI10 is almost stable. The response of the karst system to the precipitation signal has been changed, during the drought period (1990-2000), and the spring behaviour has been modified due to the first overexploitation period. Finally, overexploitation period (2001-2008) is related to the second phase of groundwater intensive pumping for irrigation purposes. Consequently, this period is completely catastrophic causing the drying up of the spring. The decreasing trends analyzed using DPI and DQI showed annual decreasing rates relative to the mean values of -0.268% and -0.105%, respectively. Thus, the results of theoretical model reveal that precipitation will decrease by about DPI = -20.7% and the discharge will decline by about -9.2% by 2050. Consequently, the declining discharge due to climatic variation under natural conditions as

  13. An approach to managing cumulative effects to groundwater resources in the Alberta oil sands

    International Nuclear Information System (INIS)

    Fennell, J.; Forrest, Francine; Klebek, Margaret

    2011-01-01

    In the Athabasca region of Northern Alberta, oil sands activity has raised many concerns over how mining and extracting processes might affect groundwater quality and quantity. The groundwater management framework was developed by Alberta Environment to address these concerns by identifying and managing the potential environmental effects of oil sands activity on groundwater in a science-based manner. This paper develops the framework using risk identification and performance monitoring. The decision-making approach was conducted using decision support tools such as modeling, monitoring and management. Results showed the complexity and variability of groundwater conditions in the Athabasca region and pointed out that knowledge in this area is still developing. This paper presented how the groundwater management framework was developed and pointed out that it will have to be updated as new information arrives.

  14. Cumulative Effects of Multiple Forms of Violence and Abuse on Women.

    Science.gov (United States)

    MacIntosh, Judith; Wuest, Judith; Ford-Gilboe, Marilyn; Varcoe, Colleen

    2015-01-01

    Little is known about how patterns of workplace bullying contribute to the negative effects of lifetime violence. Analysis of longitudinal data from a study of women's health after separating from an abusive partner revealed that 76% of 229 women had experienced workplace bullying. Workplace bullying was associated with child sexual abuse, adult sexual assault, and ongoing partner abuse. Timing was critical, with those experiencing past workplace bullying having poorer health and fewer personal and social resources than those experiencing none, ongoing, or past and ongoing bullying. Lifetime sexual harassment (54%) was associated with higher posttraumatic stress disorder symptomology and greater likelihood of leaving workplaces and physical bullying (16%) with poorer health and personal, social, and economic resources. These findings highlight the importance of including bullying in studying lifetime violence.

  15. Development of a "Hydrologic Equivalent Wetland" Concept for Modeling Cumulative Effects of Wetlands on Watershed Hydrology

    Science.gov (United States)

    Wang, X.; Liu, T.; Li, R.; Yang, X.; Duan, L.; Luo, Y.

    2012-12-01

    Wetlands are one of the most important watershed microtopographic features that affect, in combination rather than individually, hydrologic processes (e.g., routing) and the fate and transport of constituents (e.g., sediment and nutrients). Efforts to conserve existing wetlands and/or to restore lost wetlands require that watershed-level effects of wetlands on water quantity and water quality be quantified. Because monitoring approaches are usually cost or logistics prohibitive at watershed scale, distributed watershed models, such as the Soil and Water Assessment Tool (SWAT), can be a best resort if wetlands can be appropriately represented in the models. However, the exact method that should be used to incorporate wetlands into hydrologic models is the subject of much disagreement in the literature. In addition, there is a serious lack of information about how to model wetland conservation-restoration effects using such kind of integrated modeling approach. The objectives of this study were to: 1) develop a "hydrologic equivalent wetland" (HEW) concept; and 2) demonstrate how to use the HEW concept in SWAT to assess effects of wetland restoration within the Broughton's Creek watershed located in southwestern Manitoba of Canada, and of wetland conservation within the upper portion of the Otter Tail River watershed located in northwestern Minnesota of the United States. The HEWs were defined in terms of six calibrated parameters: the fraction of the subbasin area that drains into wetlands (WET_FR), the volume of water stored in the wetlands when filled to their normal water level (WET_NVOL), the volume of water stored in the wetlands when filled to their maximum water level (WET_MXVOL), the longest tributary channel length in the subbasin (CH_L1), Manning's n value for the tributary channels (CH_N1), and Manning's n value for the main channel (CH_N2). The results indicated that the HEW concept allows the nonlinear functional relations between watershed processes

  16. Recurrence and frequency of disturbance have cumulative effect on methanotrophic activity, abundance, and community structure.

    Directory of Open Access Journals (Sweden)

    Adrian eHo

    2016-01-01

    Full Text Available Alternate prolonged drought and heavy rainfall is predicted to intensify with global warming. Desiccation-rewetting events alter the soil quality and nutrient concentrations which drive microbial-mediated processes, including methane oxidation, a key biogeochemical process catalyzed by methanotrophic bacteria. Although aerobic methanotrophs showed remarkable resilience to a suite of physical disturbances induced as a single event, their resilience to recurring disturbances is less known. Here, using a rice field soil in a microcosm study, we determined whether recurrence and frequency of desiccation-rewetting impose an accumulating effect on the methanotrophic activity. The response of key aerobic methanotroph subgroups (type Ia, Ib, and II were monitored using qPCR assays, and was supported by a t-RFLP analysis. The methanotrophic activity was resilient to recurring desiccation-rewetting, but increasing the frequency of the disturbance by two-fold significantly decreased methane uptake rate. Both the qPCR and t-RFLP analyses were congruent, showing the dominance of type Ia/Ib methanotrophs prior to disturbance, and after disturbance, the recovering community was predominantly comprised of type Ia (Methylobacter methanotrophs. Both type Ib and type II (Methylosinus/Methylocystis methanotrophs were adversely affected by the disturbance, but type II methanotrophs showed recovery over time, indicating relatively higher resilience to the disturbance. This revealed distinct, yet unrecognized traits among the methanotroph community members. Our results show that recurring desiccation-rewetting before a recovery in community abundance had an accumulated effect, compromising methanotrophic activity. While methanotrophs may recover well following sporadic disturbances, their resilience may reach a ‘tipping point’ where activity no longer recovered if disturbance persists and increase in frequency.

  17. The effect of recovery strategies on physical performance and cumulative fatigue in competitive basketball.

    Science.gov (United States)

    Montgomery, Paul G; Pyne, David B; Hopkins, Will G; Dorman, Jason C; Cook, Katherine; Minahan, Clare L

    2008-09-01

    To evaluate the effectiveness of recovery strategies on physical performance during a 3-day tournament style basketball competition, 29 male players (mean age 19.1 years, s= 2.1; height 1.84 m, s= 0.34; body mass 88.5 kg, s= 14.7) were assigned to one of three treatment groups: carbohydrate+stretching (7.7 g kg(-1) day(-1), s= 1.7; 'n = 9), cold water immersion (11 degrees C, 5 x 1; n = 10) or full leg compression garments (18 mmHg, approximately 18 h; n = 10). Effects of the recovery strategies on pre-post tournament performance tests were expressed as the mean change (% +/- standard deviation of the change score). Changes and differences were standardized for accumulated game time, assessed against the smallest worthwhile change for each test, and reported qualitatively. Accumulated fatigue was evident over the tournament with small to moderate impairments in performance tests. Sprint and agility performance decreased by 0.7% (s = 1.3) and 2.0% (s = 1.9) respectively. Vertical jump decreased substantially after the first day for all treatments, and remained suppressed post-tournament. Cold water immersion was substantially better in maintaining 20-m acceleration with only a 0.5% (s = 1.4) reduction in 20-m time after 3 days compared with a 3.2% (s = 1.6) reduction for compression. Cold water immersion (-1.4%, s = 1.7) and compression (-1.5%, s = 1.7) showed similar substantial benefits in maintaining line-drill performance over the tournament, whereas carbohydrate+stretching elicited a 0.4% (s =1.8) reduction. Sit-and-reach flexibility decreased for all groups, although cold water immersion resulted in the smallest reduction in flexibility. Basketball tournament play elicited small to moderate impairments in physical test performance. In conclusion, cold water immersion appears to promote better restoration of physical performance measures than carbohydrate + stretching routines and compression garments.

  18. Cumulative effect of sulfur and calcium on wheat growth and yield under saline-sodic soils

    International Nuclear Information System (INIS)

    Arshadullah, M.; Hyder, S.I.

    2013-01-01

    A field experiment was carried out to investigate the effect of three rates of gypsum on growth and ionic concentration of wheat variety (Saher) sown in saline-sodic soil (ECe=5.32 dS m , pH=8.52 and SAR=18.87) at Soil Salinity Research Institute (SSRI) Farm, Pindi Bhattian during rabi 2009-10. Treatments were arranged using randomized complete block design (RCBD) with three replications. The crop was harvested at maturity, data on tillering, plant height, spike length, number of grains spike , 1000-grain weight, straw and paddy yields were recorded. Potassium (K), Na, Ca, S and Mg concentrations in grain were estimated using atomic absorption spectroscopy. Tillering, grains spike , 1000-grain weight and paddy yield significantly (P = 0.05) enhanced by increasing the rate of gypsum (CaSO/sub 4/). The maximum 4 number of grains spike (60), 1000-grain weight (47 g) and grain yields (4.01 t ha ) were recorded with CaSO application at the rate 150 kg ha . Grain 4 yield was 43% more than control treatment. Positive correlations (r2+ + 0.96), (r=0.96) and (r=0.91) between Ca , K , S and negative correlation r+ (-0.99) between Na contents in grain and wheat grain yield, respectively. It indicates presence of significantly higher Ca , K contents in grain receiving CaSO/sub 4/ help plants to attain more Ca/sup 2+/ , K and S to avoid Na 4 uptake. (author)

  19. Cumulative effects of ibuprofen and air emersion in zebra mussels Dreissena polymorpha.

    Science.gov (United States)

    André, C; Gagné, F

    2017-10-01

    Municipal effluents are major source of pharmaceutical products in the environment. The purpose of this study was to examine the toxicity of a largely used drug, ibuprofen (Ibu), in Dresseina polymorpha mussels and its impact on air survival time. The mussels were exposed to increasing concentration of Ibu (0, 1, 10 and 100μg/L) for 96 at 15°C and a sub-group of mussels was maintain in air for another 96h. Post-exposure mussels (Ibu and Ibu+Air) were analyzed for weight loss, total triglycerides, neutral lipids, lipid peroxidation (LPO), arachidonate-dependent cyclooxygenase (COX) and glutathione S-transferase activity. Lipid extracts of mussel tissues were also analyzed by 1 H-nuclear resonance spectroscopy. The data revealed that mussels exposed to Ibu had increased signs of lipid oxidation, neutral lipids and decreased triglycerides, LPO and GST activity. COX activity was significantly reduced by Ibu in keeping with mode of action of the drug. Following exposure to air, increased weight loss, neutral lipids (lipid degradation), were observed in mussels exposed to Ibu but no changes in COX activity were observed. Air stress limited the decrease in triglycerides and the increase in GST in mussels exposed to 100μg/L Ibu indicating decreased anti-oxidant response/phase II biotransformation and limited lipid metabolism. In conclusion, exposure to Ibu has some anti-inflammatory effects to mussels based on COX activity but resulted in increased oxidative damage and lipid catabolism. Exposure to air stress could enhance some of these responses and contribute to decreased resistance to air exposures. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  20. Health effects of radiation damage

    International Nuclear Information System (INIS)

    Gasimova, K; Azizova, F; Mehdieva, K.

    2012-01-01

    Full text : A summary of the nature of radiactive contamination would be incomplete without some mention of the human health effects relatied to radioactivity and radioactive materials. Several excellent reviews at the variety of levels of detail have been written and should be consulted by the reader. Internal exposures of alpha and beta particles are important for ingested and inhaled radionuclides. Dosimetry models are used to estimate the dose from internally deposited radioactive particles. As mentioned above weighting parameters that take into account the radiation type, the biological half-life and the tissue or organ at risk are used to convert the physically absorbed dose in units of gray (or red) to the biologically significant committed equivalent dose and effective dose, measured in units of Sv (or rem). There is considerable controversy over the shape of the dose-response curve at the chronic low dose levels important for enviromental contamination. Proposed models include linear models, non-linear models and threshold models. Because risks at low dose must be extrapolated from available date at high doses, the shape of the dose-response curve has important implications for the environmental regulations used to protect the general public. The health effect of radiation damage depends on a combination of events of on the cellular, tissue and systemic levels. These lead to mutations and cellular of the irradiated parent cell. The dose level at which significant damage occurs depends on the cell type. Cells that reproduce rapidily, such as those found in bone marrow or the gastrointestinal tract, will be more sensitive to radiation than those that are longer lived, such as striated muscle or nerve cells. The effects of high radiation doses on an organ depends on the various cell types it contains

  1. The challenge of cumulative impacts

    Energy Technology Data Exchange (ETDEWEB)

    Masden, Elisabeth

    2011-07-01

    Full text: As governments pledge to combat climate change, wind turbines are becoming a common feature of terrestrial and marine environments. Although wind power is a renewable energy source and a means of reducing carbon emissions, there is a need to ensure that the wind farms themselves do not damage the environment. There is particular concern over the impacts of wind farms on bird populations, and with increasing numbers of wind farm proposals, the concern focuses on cumulative impacts. Individually, a wind farm, or indeed any activity/action, may have minor effects on the environment, but collectively these may be significant, potentially greater than the sum of the individual parts acting alone. Cumulative impact assessment is a legislative requirement of environmental impact assessment but such assessments are rarely adequate restricting the acquisition of basic knowledge about the cumulative impacts of wind farms on bird populations. Reasons for this are numerous but a recurring theme is the lack of clear definitions and guidance on how to perform cumulative assessments. Here we present a conceptual framework and include illustrative examples to demonstrate how the framework can be used to improve the planning and execution of cumulative impact assessments. The core concept is that explicit definitions of impacts, actions and scales of assessment are required to reduce uncertainty in the process of assessment and improve communication between stake holders. Only when it is clear what has been included within a cumulative assessment, is it possible to make comparisons between developments. Our framework requires improved legislative guidance on the actions to include in assessments, and advice on the appropriate baselines against which to assess impacts. Cumulative impacts are currently considered on restricted scales (spatial and temporal) relating to individual development assessments. We propose that benefits would be gained from elevating cumulative

  2. Effects of cumulative risk on behavioral and psychological well-being in first grade: moderation by neighborhood context.

    Science.gov (United States)

    Lima, Julie; Caughy, Margaret; Nettles, Saundra M; O'Campo, Patricia J

    2010-10-01

    This study builds upon existing research by examining whether risk indices for child psychological well-being behave in the same way in different types of neighborhoods. Specifically, we sought to determine if neighborhood characteristics acted to exacerbate or, alternatively, to buffer risk factors at the family and/or child level. Families with a child entering first grade in Fall 2002 were recruited from Baltimore City neighborhoods, defined as census block groups. This study included 405 children, and data came from an interview with the primary caregiver and an assessment of the first grader. The dependent variables were externalizing behavior and internalizing problems. A family risk index consisting of 13 measures, and a child risk index consisting of three measures were the main independent variables of interest. We examined the effects of these indices on child psychological well-being and behavior across two neighborhood characteristics: neighborhood potential for community involvement with children and neighborhood negative social climate. Results of multivariate analyses indicated that cumulative family risk was associated with an increase in both internalizing and externalizing behavior problems. Perceived negative social climate moderated the effect of family risks on behavior problems such that more risk was associated with a larger increment in both externalizing behavior problems and psychological problems for children living in high versus low risk neighborhoods. These findings further emphasize the importance of considering neighborhood context in the study of child psychological well-being. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Genetic and somatic effects of ionizing radiation

    International Nuclear Information System (INIS)

    1986-01-01

    This is the ninth substantive report of the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) to the General Assembly. This report contains reviews on three special topics in the field of biological effects of ionizing radiation that are among those presently under consideration by the Committee: genetic effects of radiation, dose-response relationships for radiation-induced cancer and biological effects of pre-natal irradiation

  4. Radiation effects and soft errors in integrated circuits and electronic devices

    CERN Document Server

    Fleetwood, D M

    2004-01-01

    This book provides a detailed treatment of radiation effects in electronic devices, including effects at the material, device, and circuit levels. The emphasis is on transient effects caused by single ionizing particles (single-event effects and soft errors) and effects produced by the cumulative energy deposited by the radiation (total ionizing dose effects). Bipolar (Si and SiGe), metal-oxide-semiconductor (MOS), and compound semiconductor technologies are discussed. In addition to considering the specific issues associated with high-performance devices and technologies, the book includes th

  5. Non-thermal continuous and modulated electromagnetic radiation fields effects on sleep EEG of rats☆

    Science.gov (United States)

    Mohammed, Haitham S.; Fahmy, Heba M.; Radwan, Nasr M.; Elsayed, Anwar A.

    2012-01-01

    In the present study, the alteration in the sleep EEG in rats due to chronic exposure to low-level non-thermal electromagnetic radiation was investigated. Two types of radiation fields were used; 900 MHz unmodulated wave and 900 MHz modulated at 8 and 16 Hz waves. Animals has exposed to radiation fields for 1 month (1 h/day). EEG power spectral analyses of exposed and control animals during slow wave sleep (SWS) and rapid eye movement sleep (REM sleep) revealed that the REM sleep is more susceptible to modulated radiofrequency radiation fields (RFR) than the SWS. The latency of REM sleep increased due to radiation exposure indicating a change in the ultradian rhythm of normal sleep cycles. The cumulative and irreversible effect of radiation exposure was proposed and the interaction of the extremely low frequency radiation with the similar EEG frequencies was suggested. PMID:25685416

  6. Non-thermal continuous and modulated electromagnetic radiation fields effects on sleep EEG of rats

    Directory of Open Access Journals (Sweden)

    Haitham S. Mohammed

    2013-03-01

    Full Text Available In the present study, the alteration in the sleep EEG in rats due to chronic exposure to low-level non-thermal electromagnetic radiation was investigated. Two types of radiation fields were used; 900 MHz unmodulated wave and 900 MHz modulated at 8 and 16 Hz waves. Animals has exposed to radiation fields for 1 month (1 h/day. EEG power spectral analyses of exposed and control animals during slow wave sleep (SWS and rapid eye movement sleep (REM sleep revealed that the REM sleep is more susceptible to modulated radiofrequency radiation fields (RFR than the SWS. The latency of REM sleep increased due to radiation exposure indicating a change in the ultradian rhythm of normal sleep cycles. The cumulative and irreversible effect of radiation exposure was proposed and the interaction of the extremely low frequency radiation with the similar EEG frequencies was suggested.

  7. Health and Academic Achievement: Cumulative Effects of Health Assets on Standardized Test Scores Among Urban Youth in the United States*

    Science.gov (United States)

    Ickovics, Jeannette R.; Carroll-Scott, Amy; Peters, Susan M.; Schwartz, Marlene; Gilstad-Hayden, Kathryn; McCaslin, Catherine

    2014-01-01

    Background The Institute of Medicine (2012) concluded that we must “strengthen schools as the heart of health.” To intervene for better outcomes in both health and academic achievement, identifying factors that impact children is essential. Study objectives are to (1) document associations between health assets and academic achievement, and (2) examine cumulative effects of these assets on academic achievement. Methods Participants include 940 students (grades 5 and 6) from 12 schools randomly selected from an urban district. Data include physical assessments, fitness testing, surveys, and district records. Fourteen health indicators were gathered including physical health (eg, body mass index [BMI]), health behaviors (eg, meeting recommendations for fruit/vegetable consumption), family environment (eg, family meals), and psychological well-being (eg, sleep quality). Data were collected 3-6 months prior to standardized testing. Results On average, students reported 7.1 health assets out of 14. Those with more health assets were more likely to be at goal for standardized tests (reading/writing/mathematics), and students with the most health assets were 2.2 times more likely to achieve goal compared with students with the fewest health assets (both p student health may also improve academic achievement, closing equity gaps in both health and academic achievement. PMID:24320151

  8. Cumulative Effects of Nutrient Enrichment and Elevated Temperature Compromise the Early Life History Stages of the Coral Acropora tenuis.

    Science.gov (United States)

    Humanes, Adriana; Noonan, Sam H C; Willis, Bette L; Fabricius, Katharina E; Negri, Andrew P

    2016-01-01

    Inshore coral reefs are experiencing the combined pressures of excess nutrient availability associated with coastal activities and warming seawater temperatures. Both pressures are known to have detrimental effects on the early life history stages of hard corals, but studies of their combined effects on early demographic stages are lacking. We conducted a series of experiments to test the combined effects of nutrient enrichment (three levels) and elevated seawater temperature (up to five levels) on early life history stages of the inshore coral Acropora tenuis, a common species in the Indo-Pacific and Red Sea. Gamete fertilization, larval survivorship and larval settlement were all significantly reduced as temperature increased, but only fertilization was further affected by simultaneous nutrient enrichment. Combined high temperatures and nutrient enrichment affected fertilization in an additive manner, whereas embryo abnormalities increased synergistically. Higher than normal temperatures (32°C) increased coral juvenile growth rates 1.6-fold, but mortality also increased by 50%. The co-occurrence of nutrient enrichment with high temperatures reduced juvenile mortality to 36%, ameliorating temperature stress (antagonistic interaction). Overall, the types of effect (additive vs synergistic or antagonistic) and their magnitude varied among life stages. Gamete and embryo stages were more affected by temperature stress and, in some cases, also by nutrient enrichment than juveniles. The data suggest that coastal runoff events might exacerbate the impacts of warming temperatures on fertilization if these events co-occur during corals spawning. The cumulative impacts of simultaneous exposure to nutrient enrichment and elevated temperatures over all early life history stages increases the likelihood for failure of larval supply and recruitment for this coral species. Our results suggest that improving the water quality of river discharges into coastal areas might help to

  9. Cumulative Effects of Nutrient Enrichment and Elevated Temperature Compromise the Early Life History Stages of the Coral Acropora tenuis

    Science.gov (United States)

    Noonan, Sam H. C.; Willis, Bette L.; Fabricius, Katharina E.; Negri, Andrew P.

    2016-01-01

    Inshore coral reefs are experiencing the combined pressures of excess nutrient availability associated with coastal activities and warming seawater temperatures. Both pressures are known to have detrimental effects on the early life history stages of hard corals, but studies of their combined effects on early demographic stages are lacking. We conducted a series of experiments to test the combined effects of nutrient enrichment (three levels) and elevated seawater temperature (up to five levels) on early life history stages of the inshore coral Acropora tenuis, a common species in the Indo-Pacific and Red Sea. Gamete fertilization, larval survivorship and larval settlement were all significantly reduced as temperature increased, but only fertilization was further affected by simultaneous nutrient enrichment. Combined high temperatures and nutrient enrichment affected fertilization in an additive manner, whereas embryo abnormalities increased synergistically. Higher than normal temperatures (32°C) increased coral juvenile growth rates 1.6-fold, but mortality also increased by 50%. The co-occurrence of nutrient enrichment with high temperatures reduced juvenile mortality to 36%, ameliorating temperature stress (antagonistic interaction). Overall, the types of effect (additive vs synergistic or antagonistic) and their magnitude varied among life stages. Gamete and embryo stages were more affected by temperature stress and, in some cases, also by nutrient enrichment than juveniles. The data suggest that coastal runoff events might exacerbate the impacts of warming temperatures on fertilization if these events co-occur during corals spawning. The cumulative impacts of simultaneous exposure to nutrient enrichment and elevated temperatures over all early life history stages increases the likelihood for failure of larval supply and recruitment for this coral species. Our results suggest that improving the water quality of river discharges into coastal areas might help to

  10. Ionising radiation - physical and biological effects

    International Nuclear Information System (INIS)

    Holter, Oe.; Ingebretsen, F.; Parr, H.

    1979-01-01

    The physics of ionising radiation is briefly presented. The effects of ionising radiation on biological cells, cell repair and radiosensitivity are briefly treated, where after the effects on man and mammals are discussed and related to radiation doses. Dose limits are briefly discussed. The genetic effects are discussed separately. Radioecology is also briefly treated and a table of radionuclides deriving from reactors, and their radiation is given. (JIW)

  11. Radiation effects on microelectronics in space

    International Nuclear Information System (INIS)

    Srour, J.R.; McGarrity, J.M.

    1988-01-01

    The basic mechanisms of space radiation effects on microelectronics are reviewed in this paper. Topics discussed include the effects of displacement damage and ionizing radiation on devices and circuits, single event phenomena, dose enhancement, radiation effects on optoelectronic devices and passive components, hardening approaches, and simulation of the space radiation environment. A summary is presented of damage mechanisms that can cause temporary or permanent failure of devices and circuits operating in space

  12. Cumulative Poisson Distribution Program

    Science.gov (United States)

    Bowerman, Paul N.; Scheuer, Ernest M.; Nolty, Robert

    1990-01-01

    Overflow and underflow in sums prevented. Cumulative Poisson Distribution Program, CUMPOIS, one of two computer programs that make calculations involving cumulative Poisson distributions. Both programs, CUMPOIS (NPO-17714) and NEWTPOIS (NPO-17715), used independently of one another. CUMPOIS determines cumulative Poisson distribution, used to evaluate cumulative distribution function (cdf) for gamma distributions with integer shape parameters and cdf for X (sup2) distributions with even degrees of freedom. Used by statisticians and others concerned with probabilities of independent events occurring over specific units of time, area, or volume. Written in C.

  13. Effect of radiation in radiotherapy

    International Nuclear Information System (INIS)

    Hirata, Hideki; Fujibuchi, Toshio; Saito, Tsutomu

    2013-01-01

    The title subject is easily explained for the deterministic effect, secondary cancer formation and case reports of accidental exposure at radiotherapy. For the deterministic effect, the dose-effect relationship is sigmoidal in normal and cancer tissues, and the more separated are their curves, the more favorable is the radiotherapy. TD 5/5 is the tolerable dose to yield <5% of irreversible radiation injury to the normal tissue within 5 years after the therapy and is generally dose-limiting. The curves are of various shapes depending on the tissue composition that its functional subunit (FSU) is parallel like lobules of the liver, or in series like neuron. Symptoms appear complicated on these factors. Recent development of CT-based therapeutic planning has made it possible to analyze the partial tissue volume to be irradiated and its absorbed dose by the relationship (dose volume histogram, DVH) between the electron density vs CT value regardless to anatomy. The normal tissue complication probability is a model composed from the physical DVH and biological factors of FSU composition and cellular radiation susceptibility, and is a measure of the irreversible late effect manifested in normal tissues. Epidemiology has shown the increased risk of secondary cancer formation by radiotherapy. Children are highly susceptible to this, and in adults undergoing the therapy of a certain cancer, it is known that the risk of radiation carcinogenesis is increased in the particular tissue. There are presented such case reports of accidental excessive exposure at radiotherapy as caused by an inappropriate use of detector, partial loss of data in a therapeutic planning device, reading of reversed MRI image, and too much repeated use of the old-type electric portal imaging device. (T.T.)

  14. Radiation Effects in Nuclear Ceramics

    Directory of Open Access Journals (Sweden)

    L. Thomé

    2012-01-01

    Full Text Available Due to outstanding physicochemical properties, ceramics are key engineering materials in many industrial domains. The evaluation of the damage created in ceramics employed in radiative media is a challenging problem for electronic, space, and nuclear industries. In this latter field, ceramics can be used as immobilization forms for radioactive wastes, inert fuel matrices for actinide transmutation, cladding materials for gas-cooled fission reactors, and structural components for fusion reactors. Information on the radiation stability of nuclear materials may be obtained by simulating the different types of interactions involved during the slowing down of energetic particles with ion beams delivered by various types of accelerators. This paper presents a review of the radiation effects occurring in nuclear ceramics, with an emphasis on recent results concerning the damage accumulation processes. Energetic ions in the KeV-GeV range are used to explore the nuclear collision (at low energy and electronic excitation (at high energy regimes. The recovery by electronic excitation of the damage created by ballistic collisions (SHIBIEC process is also addressed.

  15. Integrating LANDIS model and a multi-criteria decision-making approach to evaluate cumulative effects of forest management in the Missouri Ozarks, USA

    Science.gov (United States)

    Zong Bo Shang; Hong S. He; Weimin Xi; Stephen R. Shifley; Brian J. Palik

    2012-01-01

    Public forest management requires consideration of numerous objectives including protecting ecosystem health, sustaining habitats for native communities, providing sustainable forest products, and providing noncommodity ecosystem services. It is difficult to evaluate the long-term, cumulative effects and tradeoffs these and other associated management objectives. To...

  16. Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis.

    Science.gov (United States)

    Weksler, B B; Tack-Goldman, K; Subramanian, V A; Gay, W A

    1985-02-01

    The relationship between the antithrombotic and antiplatelet effects of aspirin is complex, since aspirin influences other systems that protect against thrombosis as well as inhibiting platelet function. We investigated possible cumulative effects of low-dose aspirin on vascular production of prostacyclin in patients with documented atherosclerotic cardiovascular disease. Candidates for coronary artery vein graft bypass ingested 20 mg of aspirin daily during the week before surgery, and platelet aggregation, platelet formation of thromboxane A2 (TXA2), aortic and saphenous vein production of prostacyclin (PGI2), and hemostatic status were measured at the time of the bypass surgery. Low-dose aspirin markedly inhibited platelet aggregation responses and reduced TXA2 generation by greater than 90%, effects similar to those observed with much higher doses of aspirin. Both aortic and saphenous vein production of PGI2 were inhibited by 50% compared with PGI2 produced by vascular tissues of control subjects who received no aspirin preoperatively (51 +/- 10 pg 6-keto-PGF1 alpha/mg aortic wet weight [mean +/- SEM] in aspirin-treated subjects vs 130 +/- 16 pg/mg in control subjects, and 71 +/- 8 pg/mg saphenous vein wet weight vs 131 +/- 17 pg/mg). Blood loss at surgery was not significantly increased by preoperative low-dose aspirin as measured by chest tube drainage (754 +/- 229 ml in aspirin-treated subjects vs 645 +/- 271 ml in control subjects), hematocrit nadir (31.2 +/- 1.9% vs 31.8 +/- 1.7%), or transfusions (2.2 +/- 1.3 units of red blood cells vs 2.2 +/- 1.7 units).(ABSTRACT TRUNCATED AT 250 WORDS)

  17. Estimating the cumulative effects of the nature-based tourism in a coastal dolphin population from southern Kenya

    Science.gov (United States)

    Pérez-Jorge, Sergi; Louzao, Maite; Oro, Daniel; Pereira, Thalia; Corne, Chloe; Wijtten, Zeno; Gomes, Inês; Wambua, John; Christiansen, Fredrik

    2017-06-01

    Due to the growth of nature-based tourism worldwide, behavioural studies are needed to assess the impact of this industry on wildlife populations and understand their short-term effect. Tourism impact on dolphin populations remain poorly documented in developing countries. This study investigates the effects of nature-based tourism on the behaviour of the Indo-Pacific bottlenose dolphins (Tursiops aduncus) in southern Kenya. We used Markov chain models to estimate transition probabilities between behavioural states in the presence and absence of tourist boats, and assess the overall behavioural budgets. Based on these data and the tourism intensity in the area, we quantified the potential tourist boat disturbance over the period 2006-2013. Our results demonstrated that tourist boat interactions affected dolphins' behavioural budgets, with a significant decrease in the overall amount of time travelling and an increase in diving. The average duration of travelling and resting decreased significantly in the presence of boats. Although the cumulative tourism exposure was not significant for the dolphin population at their current levels, these impacts should be taken into consideration with the potential tourism growth in the area. This is particularly important if tourism reaches periods of high intensity, as we have shown that these periods could have a significant impact for the species, particularly where home-range and core areas are highly overlap by this activity. Understanding the effect of human disturbance variations from previous years may help to predict the consequences on dolphin populations, towards achieving a more ecological and economic sustainability of the activity.

  18. Radiation effects on cell membranes

    International Nuclear Information System (INIS)

    Koeteles, G.J.

    1982-01-01

    The recent developments in the field of membrane biology of eukaryotic cells result in revival of relevant radiobiological studies. The spatial relations and chemical nature of membrane components provide rather sensitive targets. Experimental data are presented concerning the effects of relatively low doses of X-irradiation and low concentration of tritiated water (HTO) on various receptor functions - concanavalin A, cationized ferritin, poliovirus - of plasma membranes of animal and human cells which point to early and temporary disturbances of the composite structures and functions of membranes. References are given to the multifold roles of radiationinduced membrane phenomena on the development and regeneration of radiation injuries. (orig.)

  19. Radiation effects on cell membranes

    Energy Technology Data Exchange (ETDEWEB)

    Koeteles, G.J.

    1982-11-01

    The recent developments in the field of membrane biology of eukaryotic cells result in revival of relevant radiobiological studies. The spatial relations and chemical nature of membrane components provide rather sensitive targets. Experimental data are presented concerning the effects of relatively low doses of X-irradiation and low concentration of tritiated water (HTO) on various receptor functions - concanavalin A, cationized ferritin, poliovirus - of plasma membranes of animal and human cells which point to early and temporary disturbances of the composite structures and functions of membranes. References are given to the multifold roles of radiationinduced membrane phenomena on the development and regeneration of radiation injuries.

  20. Effect of radiation on food

    Energy Technology Data Exchange (ETDEWEB)

    Sofyan, R [National Atomic Energy Agency, Jakarta (Indonesia). Pasar Djumat Research Centre

    1983-07-01

    Research reports on the effect on radiation on food are reviewed. Irradiation processing inhibits the sprouting of vegetables, delays ripening, reduces the number of microorganisms that spoil food, controls patrogenic organisms and parasites found in food, disinfests food of insects, and disinfects spices of microbes. So far there has been no evidence that food irradiaton introduces nutritional or microbiological problems. The FAO/WHO/IAEA expert committee on the wholesomeness of irradiated food recommend the acceptability from a toxicological stand-point of any food commodity irradiated up to an overall average dose of 10 kilograys.

  1. Effect of radiation on food

    International Nuclear Information System (INIS)

    Sofyan, Rochestri

    1983-01-01

    Research reports on the effect on radiation on food are reviewed. Irradiation processing inhibits the sprouting of vegetables, delays ripening, reduces the number of microorganisms that spoil food, controls patrogenic organisms and parasites found in food, disinfests food of insects, and disinfects spices of microbes. So far there has been no evidence that food irradiaton introduces nutritional or microbiological problems. The FAO/WHO/IAEA expert committee on the wholesomeness of irradiated food recommend the acceptability from a toxicological stand-point of any food commodity irradiated up to an overall average dose of 10 kilograys. (RUW)

  2. Effects of radiation upon gastrointestinal motility

    Institute of Scientific and Technical Information of China (English)

    Mary F Otterson

    2007-01-01

    Whether due to therapeutic or belligerent exposure, the gastrointestinal effects of irradiation produce symptoms dreaded by a majority of the population. Nausea, vomiting, diarrhea and abdominal cramping are hallmarks of the prodromal phase of radiation sickness, occurring hours to days following radiation exposure. The prodromal phase is distinct from acute radiation sickness in that the absorptive, secretory and anatomic changes associated with radiation damage are not easily identifiable. It is during this phase of radiation sickness that gastrointestinal motility significantly changes. In addition, there is evidence that motor activity of the gut contributes to some of the acute and chronic effects of radiation.

  3. The Brookhaven Radiation Effects Facility

    Energy Technology Data Exchange (ETDEWEB)

    Grand, P.; Snead, C.L.; Ward, T.

    1988-01-01

    The Neutral Particle Beam (NPB) Radiation Effects Facility (REF), funded by the Strategic Defense Initiative Office (SDIO) through the Defense Nuclear Agency (DNA) and the Air Force Weapons Laboratory (AFWL), has been constructed at Brookhaven National Laboratory (BNL). Operation started in October 1986. The facility is capable of delivering pulsed H{sup -}, H{sup o}, and H{sup +} beams of 100 to 200 MeV energy up to 30 mA peak current. Pulses can be adjusted from 5 {mu}s to 500 {mu}s length at a repetition rate of 5 pps. The beam spot on target is adjustable from 3 to 100 cm diameter (2 {sigma}) resulting in a maximum dose of about 10 MRads (Si) per pulse (small beam spot). Experimental use of the REF is being primarily supported by the SDI lethality (LTH-4) program. The program has addressed ionization effects in electronics, both dose rate and total dose dependence, radiation-sensitive components, and dE/dx effects in energetic materials including propellants and high explosives (HE). This paper describes the facility, its capabilities and potential, and the experiments that have been carried out to date or are being planned. 2 refs., 10 figs.

  4. The Brookhaven Radiation Effects Facility

    International Nuclear Information System (INIS)

    Grand, P.; Snead, C.L.; Ward, T.

    1988-01-01

    The Neutral Particle Beam (NPB) Radiation Effects Facility (REF), funded by the Strategic Defense Initiative Office (SDIO) through the Defense Nuclear Agency (DNA) and the Air Force Weapons Laboratory (AFWL), has been constructed at Brookhaven National Laboratory (BNL). Operation started in October 1986. The facility is capable of delivering pulsed H - , H/sup o/, and H + beams of 100 to 200 MeV energy up to 30 mA peak current. Pulses can be adjusted from 5 μs to 500 μs length at a repetition rate of 5 pps. The beam spot on target is adjustable from 3 to 100 cm diameter (2 σ) resulting in a maximum dose of about 10 MRads (Si) per pulse (small beam spot). Experimental use of the REF is being primarily supported by the SDI lethality (LTH-4) program. The program has addressed ionization effects in electronics, both dose rate and total dose dependence, radiation-sensitive components, and dE/dx effects in energetic materials including propellants and high explosives (HE). This paper describes the facility, its capabilities and potential, and the experiments that have been carried out to date or are being planned. 2 refs., 10 figs

  5. Effects of radiation on DNA

    International Nuclear Information System (INIS)

    Braddock, M.

    1985-07-01

    The hydroxyl radical (OH radical) is the most damaging radical produced by the effect of ionizing radiation in water. The rate of reaction of the OH radical with purified, native and isodisperse DNA has been determined as compared with calf thymus DNA. This has been achieved by direct observation of the rate of formation of the DNA-OH radical adduct, and by competition with SCN - . Results obtained from direct observation are consistent with calculations which have been performed using the encounter frequency model of Braams and Ebert. However, results obtained for OH radical with DNA derived from competition plots suggest a rate constant somewhat lower than that obtained from direct observation. The relative merits of both techniques are discussed. In order to study the effect of energy deposited directly in the DNA, dry films of purified plasmid DNA have been irradiated in a system where the indirect effects of radical interaction have been minimized. The present results indicate that with different molecular lengths of plasmid DNA, non-random breakage may occur, and that additional damage may be brought about at sites of previously existing damage. Differences in the sensitivity of plasmid DNA molecules of varying lengths to radiation induced double strand breaks have been demonstrated. (author)

  6. Cumulative effects of using pin fin heat sink and porous metal foam on thermal management of lithium-ion batteries

    International Nuclear Information System (INIS)

    Mohammadian, Shahabeddin K.; Zhang, Yuwen

    2017-01-01

    Highlights: • 3D transient thermal analysis of a pouch Li-ion cell has been carried out. • Using pin fin heat sink improves the temperature reduction at low pumping powers. • Using pin fin heat sink enhances the temperature uniformity at low air flow rates. • Porous aluminum foam insertion with pin fins improves temperature reduction. • Porous aluminum foam insertion with pin fins enhances temperature uniformity. - Abstract: Three-dimensional transient thermal analysis of an air-cooled module was carried out to investigate cumulative effects of using pin fin heat sink and porous metal foam on thermal management of a Li-ion (lithium-ion) battery pack. Five different cases were designed as Case 1: flow channel without any pin fin or porous metal foam insertion, Case 2: flow channel with aluminum pin fins, Case 3: flow channel with porous aluminum foam pin fins, Case 4: fully inserted flow channel with porous aluminum foam, and Case 5: fully inserted flow channel with porous aluminum foam and aluminum pin fins. The effects of porous aluminum insertions, pin fin types, air flow inlet temperature, and air flow inlet velocity on the temperature uniformity and maximum temperature inside the battery pack were systematically investigated. The results showed that using pin fin heat sink (Case 2) is appropriate only for low air flow velocities. In addition, the use of porous aluminum pin fins or embedding porous aluminum foam inside the air flow channel (Cases 3 and 4) are not beneficial for thermal management improvement. The combination of aluminum pin fins and porous aluminum foam insertion inside the air flow channel (Case 5) is a proper option that improves both temperature reduction and temperature uniformity inside the battery cell.

  7. Effects of ionizing radiation on vitamins

    International Nuclear Information System (INIS)

    Thayer, D.W.; Fox, J.B. Jr.; Lakritz, L.

    1991-01-01

    Vitamins are known to be sensitive to the effects of ionizing radiation. Since most foods contain a large proportion of water, the most probable reaction of the ionizing radiation would be with water; and as vitamins are present in very small amounts compared with other substances in the food they will be affected indirectly by the radiation. This chapter discusses the effect of ionizing radiation on water soluble vitamins and fat soluble vitamins. (author)

  8. Radiation effects of high and low doses

    International Nuclear Information System (INIS)

    El-Naggar, A.M.

    1998-01-01

    The extensive proliferation of the uses and applications of atomic and nuclear energy resulted in possible repercussions on human health. The prominent features of the health hazards that may be incurred after exposure to high and low radiation doses are discussed. The physical and biological factors involved in the sequential development of radiation health effects and the different cellular responses to radiation injury are considered. The main criteria and features of radiation effects of high and low doses are comprehensively outlined

  9. Medical response to effects of ionising radiation

    International Nuclear Information System (INIS)

    Crosbie, W.A.; Gittus, J.H.

    1989-01-01

    The proceedings of a conference on 'Medical Response to Effects of Ionising Radiation' in 1989 in the form of nineteen papers published as a book. Topics discussed include radiation accidents at nuclear facilities, the medical management of radiation casualties, the responsibilities, plans and resources for coping with a nuclear accident and finally the long term effects of radiation, including leukaemia epidemiology studies. All papers were selected and indexed separately. (UK)

  10. Effects of total dose of ionizing radiation on integrated circuits

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, Marcilei A.G.; Cirne, K.H.; Gimenez, S.; Santos, R.B.B. [Centro Universitario da FEI, Sao Bernardo do Campo, SP (Brazil); Added, N.; Barbosa, M.D.L.; Medina, N.H.; Tabacniks, M.H. [Universidade de Sao Paulo (IF/USP), SP (Brazil). Inst. de Fisica; Lima, J.A. de; Seixas Junior, L.E.; Melo, W. [Centro de Tecnologia da Informacao Paulo Archer, Sao Paulo, SP (Brazil)

    2011-07-01

    Full text: The study of ionizing radiation effects on materials used in electronic devices is of great relevance for the progress of global technological development and, particularly, it is a necessity in some strategic areas in Brazil. Electronic circuits are strongly influenced by radiation and the need for IC's featuring radiation hardness is largely growing to meet the stringent environment in space electronics. On the other hand, aerospace agencies are encouraging both scientific community and semiconductors industry to develop hardened-by-design components using standard manufacturing processes to achieve maximum performance, while significantly reducing costs. To understand the physical phenomena responsible for changes in devices exposed to ionizing radiation several kinds of radiation should then be considered, among them alpha particles, protons, gamma and X-rays. Radiation effects on the integrated circuits are usually divided into two categories: total ionizing dose (TID), a cumulative dose that shifts the threshold voltage and increases transistor's off-state current; single events effects (SEE), a transient effect which can deposit charge directly into the device and disturb the properties of electronic circuits. TID is one of the most common effects and may generate degradation in some parameters of the CMOS electronic devices, such as the threshold voltage oscillation, increase of the sub-threshold slope and increase of the off-state current. The effects of ionizing radiation are the creation of electron-hole pairs in the oxide layer changing operation mode parameters of the electronic device. Indirectly, there will be also changes in the device due to the formation of secondary electrons from the interaction of electromagnetic radiation with the material, since the charge carriers can be trapped both in the oxide layer and in the interface with the oxide. In this work we have investigated the behavior of MOSFET devices fabricated with

  11. Feature analysis and primary causes of pre-flood season "cumulative effect" of torrential rain over South China

    Science.gov (United States)

    Chu, Qu-cheng; Wang, Qi-guang; Qiao, Shao-bo; Feng, Guo-lin

    2018-01-01

    When persistent rainfall occurs frequently over South China, meso-scale and micro-scale synoptic systems persist and expand in space and time and eventually form meso-scale and long-scale weather processes. The accumulation of multiple torrential rain processes is defined as a "cumulative effect" of torrential rain (CETR) event. In this paper, daily reanalysis datasets collected by the National Centers for Environmental Prediction-Department of Energy (NCEP-DOE) during 1979-2014 are used to study the anomalous features and causes of heavy CETR events over South China. The results show that there is a significant difference in the spatial distribution of the heavy CETR events. Based on the center position of the CETR, the middle region displayed middle-region-heavy CETR events while the western region displayed west-region-heavy CETR events. El Niño events in the previous period (December, January, February, March (DJFM)) are major extra-forcing factors of middle-region-heavy CETR events, which is beneficial for the continuous, anomalous Philippine Sea anticyclone and strengthens the West Pacific Subtropical High (WPSH), extending it more westward than normal. The primary water vapor source for precipitation in middle-region-heavy CETR events is the Tropical Western Pacific Ocean. The major extra-forcing factor of a west-region-heavy CETR is the negative anomaly in the southern Tropical Indian Ocean (TIO) during the previous period (DJFM). This factor is beneficial for strengthening the cross-equatorial flow and westerly winds from the Bay of Bengal to the South China Sea (SCS) and early SCS summer monsoon onset. The primary water vapor source of precipitation in the west-region-heavy CETR is the southern TIO.

  12. The effect of cumulative endurance exercise on leptin and adiponectin and their role as markers to monitor training load

    Directory of Open Access Journals (Sweden)

    SC Voss

    2016-01-01

    Full Text Available Leptin and adiponectin play an essential role in energy metabolism. Leptin has also been proposed as a marker for monitoring training load. So far, no studies have investigated the variability of these hormones in athletes and how they are regulated during cumulative exercises This study monitored leptin and adiponectin in 15 endurance athletes twice daily in the days before, during and after a 9-day simulated cycling stage race. Adiponectin significantly increased during the race (p=0.001 and recovery periods (p=0.002 when compared to the baseline, while leptin decreased significantly during the race (p<0.0001 and returned to baseline levels during the recovery period. lntra-individual variability was substantially lower than inter-individual variability for both hormones (leptin 34.1 vs. 53.5%, adiponectin 19% vs. 37.2%. With regards to exercise, this study demonstrated that with sufficient, sustained energy expenditure, leptin concentrations can decrease within the first 24 hours. Under the investigated conditions there also appears to be an optimal leptin concentration which ensures stable energy homeostasis, as there was no significant decrease over the subsequent race days. ln healthy endurance athletes the recovery of leptin takes 48-72 hours and may even show a supercompensation- like effect. For adiponectin, significant increases were observed within 5 days of commencing racing, with these elevated values failing to return to baseline levels after 3 days of recovery. Additionally, when using leptin and adiponectin to monitor training loads, establishing individual threshold values improves their sensitivity.

  13. Radiation effects in the environment

    Energy Technology Data Exchange (ETDEWEB)

    Begay, F.; Rosen, L.; Petersen, D.F.; Mason, C.; Travis, B. [Los Alamos National Lab., NM (United States); Yazzie, A. [Navajo Nation, Window Rock, AZ (United States). Dept. of History; Isaac, M.C.P.; Seaborg, G.T. [Lawrence Berkeley National Lab., CA (United States); Leavitt, C.P. [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Physics and Astronomy

    1999-04-01

    Although the Navajo possess substantial resource wealth-coal, gas, uranium, water-this potential wealth has been translated into limited permanent economic or political power. In fact, wealth or potential for wealth has often made the Navajo the victims of more powerful interests greedy for the assets under limited Navajo control. The primary focus for this education workshop on the radiation effects in the environment is to provide a forum where scientists from the nuclear science and technology community can share their knowledge toward the advancement and diffusion of nuclear science and technology issues for the Navajo public. The scientists will make an attempt to consider the following basic questions; what is science; what is mathematics; what is nuclear radiation? Seven papers are included in this report: Navajo view of radiation; Nuclear energy, national security and international stability; ABC`s of nuclear science; Nuclear medicine: 100 years in the making; Radon in the environment; Bicarbonate leaching of uranium; and Computational methods for subsurface flow and transport. The proceedings of this workshop will be used as a valuable reference materials in future workshops and K-14 classrooms in Navajo communities that need to improve basic understanding of nuclear science and technology issues. Results of the Begay-Stevens research has revealed the existence of strange and mysterious concepts in the Navajo Language of nature. With these research results Begay and Stevens prepared a lecture entitled The Physics of Laser Fusion in the Navajo language. This lecture has been delivered in numerous Navajo schools, and in universities and colleges in the US, Canada, and Alaska.

  14. Inequality in the Scientific Community: The Effects of Cumulative Advantage among Social Scientists and Humanities Scholars in Korea

    Science.gov (United States)

    Kim, Keuntae; Kim, Jong-Kil

    2017-01-01

    The primary goal of this paper is to provide a balanced perspective for understanding inequality in research productivity among Korean scholars in humanities and social sciences. Specifically, we examine cumulative advantage over the careers of a sample of Korean social scientists and humanities scholars (N = 8933). Descriptive analyses indicated…

  15. Effects of ionizing radiation on life

    International Nuclear Information System (INIS)

    Rausch, L.

    1982-01-01

    Radiobiology in the last years was able to find detailed explanations for the effects of ionizing radiation on living organisms. But it is still impossible to make exact statements concerning the damages by radiation. Even now, science has to content itself with probability data. Moreover no typical damages of ionizing radiation can be identified. Therefore, the risks of ionizing radiation can only be determined by comparison with the spontaneous rate of cancerous or genetic defects. The article describes the interaction of high-energy radiation with the molecules of the organism and their consequences for radiation protection. (orig.)

  16. γ radiation effects on Collembola

    International Nuclear Information System (INIS)

    Loring, S.J.

    1985-01-01

    Pitfall traps were used to collect surface-active Collembola at intervals of 10-100 m from a γ radiation source on Long Island, N.Y., during the summer of 1968. Thirty-two species of Collembola were collected along the radiation transect. Community diversities were similar at all intervals except 10 m. Collembola appeared resistant to γ radiation; only chronic, very high γ radiation exposure seriously affected population levels and community diversity of surface Collembola

  17. Accumulative effects of regulatory actions. Exercise of analysis of CER, consideration of the cumulative Effects of regulation in the rulemaking process in Spanish NPP

    International Nuclear Information System (INIS)

    Gonzalez Ayestaran, P.; Castella, L.

    2014-01-01

    Through its interaction with the American industry, the NRC has been aware for a number of years of the concern about the impact of the accumulative effect of some regulatory actions. In response to this concern, which was highlighted by the industry, the NRC has carried out initiative to review a number of regulatory requirements order to ensure that NRC regulation and practices dno not lead to an unnecessary regulatory load. The foregoing was in response to what has become commonly known as the CER. Cumulative Effects of Regulation in the Rulemaking Process. In view of the regulatory actuation by the Spanish Nuclear Safety Council (CSN) and, in particular after the events which occurred in Japan, a pilot study has been carried out to examine the CER on a Spanish plant in order to analyse the cumulative effects of regulation and to propose improvements to the management of regulation in line with that set our by the NRC in various documents (SECY-02-081, SECY-11-0032 among others). (Authors)

  18. Effects of radiations on electronic components - Course IN2P3, release 6

    International Nuclear Information System (INIS)

    2007-01-01

    As many off-the-shelf electronic components are now present onboard satellites, launchers and planes, this course proposes an overview of effects radiations can have on these components, notably in space applications. A first part proposes an overview of radiative environments, and more particularly presents the space radiative environment (solar wind, solar flares, cosmic radiation, radiation belts). It also presents the atmospheric and Earth radiative environment due to cosmic radiation, the alpha radiation (origin of particles, particle flow), the radiative environment within an accelerator. The second part addresses the effects of these radiative environments on electronic components, and the associated standards and tests. It addresses cumulative effects and proposes a detailed analysis of the effects of an ionizing dose on a MOS transistor, an analysis of the effects of ionising dose rate on a bipolar NPN or PNP vertical or lateral transistor, an analysis of the effects of atomic displacements, and a discussion of structure modifications. The next part describes various single events: the Single Event Upset (SEU) and the Multiple Bit Upset (MBU) in the case of a SRAM, the SEL (Single Event Latch-up) phenomenon, the SEGR (Single Event Gate Rupture) phenomenon in the case of a Power MOSFET, and the SEB (Single Event Burnout) phenomenon in the case of a Power MOSFET

  19. Biologic effects of electromagnetic radiation and microwave

    International Nuclear Information System (INIS)

    Deng Hua

    2002-01-01

    Electromagnetic radiation and microwave exist mankind's environment widely. People realize they disserve authors' health when authors make use of them. Electromagnetic radiation is one of the major physic factors which injure people's health. A review of the biologic mechanism about electromagnetic radiation and microwave, their harmful effects to human body, problems in authors' research and the prospect

  20. Study of biological effect of radiation

    International Nuclear Information System (INIS)

    Li Guisheng

    1992-01-01

    The some progress on the study of biological effect for protract exposure to low dose rate radiation is reported, and it is indicated that the potential risk of this exposure for the human health and the importance of the routine monitoring of radiation dose for various nuclear installations. The potential exposure to the low dose rate radiation would attract people's extra attention

  1. Molecular and cellular effects of radiations

    International Nuclear Information System (INIS)

    Peak, M.J.; Peak, J.G.; Ito, A.; Roth, R.M.

    1985-01-01

    This program is concerned with the basic nature of the biological effects of mutagenic and carcinogenic environmental radiations, including those solar ultraviolet and visible radiations responsible for the most common form of human cancer: cancer of the skin. Concentrating on the damages to DNA caused by these radiations, the program attempts to delineate the basic mechanisms whereby such damage may occur. 14 refs

  2. Radiation effects on biochemical systems

    International Nuclear Information System (INIS)

    Seddon, G.M.

    2000-04-01

    Xanthine oxidase catalyses the oxidative hydroxylation of hypoxanthine, xanthine and a wide range of carbonyl compounds. The enzyme exists as an oxidase and a dehydrogenase; both catalyze the oxidation of the same substrates. Steady state radiolysis and pulse radiolysis were used to generate oxidative and reductive free radicals. Their effects on the enzymatic activity of xanthine oxidase were determined. Initially inactivation studies were carried out to evaluate the extent to which radiolysis in aqueous solution affects the enzyme activity. Values of D 37 and G inactivation were calculated following irradiation in the presence of free radical scavengers and in the presence of catalase and superoxide dismutase. The kinetic constants Vmax and Km were also determined following radiolysis. The effect of ionising radiation on the iron content of xanthine oxidase was measured using atomic absorption spectrometry. Native gel electrophoresis and iso-electric focussing were performed in an attempt to demonstrate changes in the overall structure of the enzyme. The binding of xanthine oxidase to heparin was carried out by measuring, (1) the displacement of methylene blue (MB + ) from a heparin-MB + complex, (2) affinity chromatography and, (3) pulse radiolysis. The effect of irradiation on the binding process was investigated using techniques (1) and (2). Finally the radiation-induced conversion of xanthine oxidase to dehydrogenase was established. The results indicate that xanthine oxidase is inactivated greatest in the presence of air and irradiation causes Vmax to he reduced and Km to increase. The iron content of irradiated xanthine oxidase is unaffected. Electrophoresis shows the enzyme becomes fragmented and the isoelectric points of the fragments vary over a wide range of pH. Binding of xanthine oxidase to heparin as measured by displacement of MB + from a heparin-MB + complex suggests that irradiation increases the affinity of the enzyme for the polyanion, whereas

  3. The effects of radiation on man

    International Nuclear Information System (INIS)

    Saunders, P.

    1981-01-01

    Available evidence on the effects of high levels of radiation on man and the predictions which have been made on possible low level effects, by extrapolation of the high level data, are summarised. The factors which influence the biological effects of radiation are examined and acute, delayed, somatic and hereditary effects as reported in the literature, are discussed. (U.K.)

  4. Quantification of the cumulative effects of river training works on the basin scale with 2D flood modelling

    Science.gov (United States)

    Zischg, Andreas Paul; Felder, Guido; WWeingartner, Rolf

    2015-04-01

    newest airborne Lidar measurements of the Canton of Bern with a point density of 4 points per square meter. The described model configuration allows routing the same worst case flood through different states of the river system and therefore to quantify the cumulative effects of all river training works.

  5. Long term effects of radiation in man

    International Nuclear Information System (INIS)

    Tso Chih Ping; Idris Besar

    1984-01-01

    An overview of the long term effects of radiation in man is presented, categorizing into somatic effects, genetic effects and teratogenic effects, and including an indication of the problems that arise in their determination. (author)

  6. Cumulative effects of wind turbines. Volume 1: Report on the preparation of a planning tool by means of consensus-building

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report summarises the results of the Cumulative Effect of Wind Turbines project which sought to develop guidance on planning and assessing the combined effects of wind energy developments in an area. Details are given of the consensus-building approach, the call for contributions, stakeholder workshops and consultation, the project research, the development and refinement of the guidance, and the completion of the final draft.

  7. Non controlled effect of ionizing radiations : involvement for radiation protection

    International Nuclear Information System (INIS)

    Little, J. B.

    2005-01-01

    It is widely accepted that damage to DNA is the critical event on irradiated cells, and that double strand breaks are the primary DNA lesions responsible for the biological effects of ionizing radiation. This has lead to the long standing paradigm that these effects, be they cytotoxicity, mutagenesis or malignant transformation, occur in irradiated cells as a consequences of the DNA damage they incur. Evidence has been accumulating over the past decade, however, to indicate that radiation may induce effects that ar not targeted to the irradiated cells itself. Two non-targeted effects will be described in this review. The first, radiation-induced genomic instability, is a phenomenon whereby signals are transmitted to the progeny of the irradiated cell over many generations, leading to the occurrence of genetic effects such as mutations and chromosomal aberrations arising in the distant descendants of the irradiated cell. Second, the bystander effect, is a phenomenon whereby irradiated cells transmit damage signals to non-irradiated cells in a mixed population, leading to genetic effects arising in these bystander cells that received no radiation exposure. the model system described in this review involves dense monolayer cultures exposed to very low fluences of alpha particles. The potential implications of these two phenomena for the analysis of the risk to the human population of exposure to low levels of ionising radiation is discussed. (Author) 111 refs

  8. Radiation effects on materials in high-radiation environments

    International Nuclear Information System (INIS)

    Weber, W.J.; Mansur, L.K.; Clinard, F.W. Jr.; Parkin, D.M.

    1991-01-01

    A workshop on Radiation Effects on Materials in High-Radiation Environments was held in Salt Lake City, Utah (USA) from August 13 to 15, 1990 under the auspices of the Division of Materials Sciences, Office of Basic Energy Sciences, US Department of Energy. The workshop focused on ceramics, alloys, and intermetallics and covered research needs and capabilities, recent experimental data, theory, and computer simulations. It was concluded that there is clearly a continuing scientific and technological need for fundamental knowledge on the underlying causes of radiation-induced property changes in materials. Furthermore, the success of many current and emerging nuclear-related technologies critically depend on renewed support for basic radiation-effects research, irradiation facilities, and training of scientists. The highlights of the workshop are reviewed and specific recommendations are made regarding research needs. (orig.)

  9. Graphene Field Effect Transistor for Radiation Detection

    Science.gov (United States)

    Li, Mary J. (Inventor); Chen, Zhihong (Inventor)

    2016-01-01

    The present invention relates to a graphene field effect transistor-based radiation sensor for use in a variety of radiation detection applications, including manned spaceflight missions. The sensing mechanism of the radiation sensor is based on the high sensitivity of graphene in the local change of electric field that can result from the interaction of ionizing radiation with a gated undoped silicon absorber serving as the supporting substrate in the graphene field effect transistor. The radiation sensor has low power and high sensitivity, a flexible structure, and a wide temperature range, and can be used in a variety of applications, particularly in space missions for human exploration.

  10. Radiation-induced polymerization and radiation effect on polymers

    International Nuclear Information System (INIS)

    Seguchi, Tadao

    1977-12-01

    The processes of radiation-induced polymerization of monomers and also radiation effects on polymers have been studied by instrumental analyses of electron spin resonance (ESR), nuclear magnetic resonance (NMR) and electron microscopy. In radiation-induced polymerization, graft-copolymerization and absorbed state polymerization were taken up. For graft-copolymerization, monomers such as methylmethacrylate and butadiene were made to react with irradiated polyethylene, and behaviors of the initiating radicals and propagating radicals were followed under the reaction by ESR. For absorbed state polymerization, acrylonitrile/zeolite and methylmethacrylate/zeolite were chosen. Absorbed monomers were irradiated at 77 0 K and polymerized at room temperature. Active species and the concentrations were measured by ESR and the yields of polymer were observed by NMR. In radiation effect on polymers, polyvinylfluoride, polyvinylidenfluoride and polytetrafluoroethylene were taken up. Active species trapped in the polymer matrixes were identified and decay and reactivity of the species were also studied. On the basis of information from the electron microscopy and x-ray analysis, radiation effects on these polymers are described. In polytetrafluoroethylene produced by radiation polymerization, the relation between morphology and polymerization conditions and also the process of crystallization during polymerization were studied. (auth.)

  11. Untargeted effects of ionizing radiation: Implications for radiation pathology

    International Nuclear Information System (INIS)

    Wright, Eric G; Coates, Philip J

    2006-01-01

    The dogma that genetic alterations are restricted to directly irradiated cells has been challenged by observations in which effects of ionizing radiation, characteristically associated with the consequences of energy deposition in the cell nucleus, arise in non-irradiated cells. These, so called, untargeted effects are demonstrated in cells that have received damaging signals produced by irradiated cells (radiation-induced bystander effects) or that are the descendants of irradiated cells (radiation-induced genomic instability). Radiation-induced genomic instability is characterized by a number of delayed adverse responses including chromosomal abnormalities, gene mutations and cell death. Similar effects, as well as responses that may be regarded as protective, have been attributed to bystander mechanisms. Whilst the majority of studies to date have used in vitro systems, some adverse non-targeted effects have been demonstrated in vivo. However, at least for haemopoietic tissues, radiation-induced genomic instability in vivo may not necessarily be a reflection of genomically unstable cells. Rather the damage may reflect responses to ongoing production of damaging signals; i.e. bystander responses, but not in the sense used to describe the rapidly induced effects resulting from direct interaction of irradiated and non-irradiated cells. The findings are consistent with a delayed and long-lived tissue reaction to radiation injury characteristic of an inflammatory response with the potential for persisting bystander-mediated damage. An important implication of the findings is that contrary to conventional radiobiological dogma and interpretation of epidemiologically-based risk estimates, ionizing radiation may contribute to malignancy and particularly childhood leukaemia by promoting initiated cells rather than being the initiating agent. Untargeted mechanisms may also contribute to other pathological consequences

  12. A-bomb radiation effects digest

    International Nuclear Information System (INIS)

    Shigematsu, Itsuzo; Akiyama, Mitoshi; Sasaki, Hideo; Ito, Chikako; Kamada, Nanao.

    1993-01-01

    This publication is the digest of the book 'Genbaku Hoshasen no Jintai Eikyo (Effects of A-bomb Radiation on the Human Body)' (365p.), published in Japanese by Hiroshima International Council for Medical Care of the Radiation-Exposed. Following a brief description on the damage of the atomic bomb, the subjects of malignant tumors, endocrine and metabolic deseases, ocular lesions, dermatologic effects, prenatal exposure, chromosoal aberrations, mutations, sensitivity to radiation, immune function, genetic effects and other effects of radiation are summarized. (J.P.N.)

  13. Cumulative Effective Hölder Exponent Based Indicator for Real-Time Fetal Heartbeat Analysis during Labour

    Science.gov (United States)

    Struzik, Zbigniew R.; van Wijngaarden, Willem J.

    We introduce a special purpose cumulative indicator, capturing in real time the cumulative deviation from the reference level of the exponent h (local roughness, Hölder exponent) of the fetal heartbeat during labour. We verify that the indicator applied to the variability component of the heartbeat coincides with the fetal outcome as determined by blood samples. The variability component is obtained from running real time decomposition of fetal heartbeat into independent components using an adaptation of an oversampled Haar wavelet transform. The particular filters used and resolutions applied are motivated by obstetricial insight/practice. The methodology described has the potential for real-time monitoring of the fetus during labour and for the prediction of the fetal outcome, allerting the attending staff in the case of (threatening) hypoxia.

  14. Divergent Cumulative Cultural Evolution

    OpenAIRE

    Marriott, Chris; Chebib, Jobran

    2016-01-01

    Divergent cumulative cultural evolution occurs when the cultural evolutionary trajectory diverges from the biological evolutionary trajectory. We consider the conditions under which divergent cumulative cultural evolution can occur. We hypothesize that two conditions are necessary. First that genetic and cultural information are stored separately in the agent. Second cultural information must be transferred horizontally between agents of different generations. We implement a model with these ...

  15. Long-term effects of ionizing radiation

    International Nuclear Information System (INIS)

    Kaul, Alexander; Burkart, Werner; Grosche, Bernd; Jung, Thomas; Martignoni, Klaus; Stephan, Guenther

    1997-01-01

    This paper approaches the long-term effects of ionizing radiation considering the common thought that killing of cells is the basis for deterministic effects and that the subtle changes in genetic information are important in the development of radiation-induced cancer, or genetic effects if these changes are induced in germ cells

  16. Quantification of tillage, plant cover, and cumulative rainfall effects on soil surface microrelief by statistical, geostatistical and fractal indices

    Science.gov (United States)

    Paz-Ferreiro, J.; Bertol, I.; Vidal Vázquez, E.

    2008-07-01

    Changes in soil surface microrelief with cumulative rainfall under different tillage systems and crop cover conditions were investigated in southern Brazil. Surface cover was none (fallow) or the crop succession maize followed by oats. Tillage treatments were: 1) conventional tillage on bare soil (BS), 2) conventional tillage (CT), 3) minimum tillage (MT) and 4) no tillage (NT) under maize and oats. Measurements were taken with a manual relief meter on small rectangular grids of 0.234 and 0.156 m2, throughout growing season of maize and oats, respectively. Each data set consisted of 200 point height readings, the size of the smallest cells being 3×5 cm during maize and 2×5 cm during oats growth periods. Random Roughness (RR), Limiting Difference (LD), Limiting Slope (LS) and two fractal parameters, fractal dimension (D) and crossover length (l) were estimated from the measured microtopographic data sets. Indices describing the vertical component of soil roughness such as RR, LD and l generally decreased with cumulative rain in the BS treatment, left fallow, and in the CT and MT treatments under maize and oats canopy. However, these indices were not substantially affected by cumulative rain in the NT treatment, whose surface was protected with previous crop residues. Roughness decay from initial values was larger in the BS treatment than in CT and MT treatments. Moreover, roughness decay generally tended to be faster under maize than under oats. The RR and LD indices decreased quadratically, while the l index decreased exponentially in the tilled, BS, CT and MT treatments. Crossover length was sensitive to differences in soil roughness conditions allowing a description of microrelief decay due to rainfall in the tilled treatments, although better correlations between cumulative rainfall and the most commonly used indices RR and LD were obtained. At the studied scale, parameters l and D have been found to be useful in interpreting the configuration properties of

  17. The cumulative effect of smoking at age 50, 60, and 70 on functional ability at age 75

    DEFF Research Database (Denmark)

    Støvring, Nina; Avlund, Kirsten; Schultz-Larsen, Kirsten

    2004-01-01

    of accumulating the smoking habits over the examinations. Cumulated former smokers have a larger risk of having reduced functional ability at age 75 (OR: 1.35 (1.13-1.61)) compared with never smokers. The odds ratios of reduced functional ability were 2.46 (1.44-4.17) among cumulated smokers of 1-14 grams......AIMS: As elderly people form a steadily growing part of the population in most parts of the world we are in need of knowledge of the influence of modifiable lifestyle factors on functional ability late in life. This study aims to examine the cumulative impact of smoking from age 50 to 70...... on functional ability at age 75. METHODS: 387 men and women born in 1914 and living in seven municipalities in the western part of the County of Copenhagen were followed for 25 years with examinations in 1964, 1974, 1984, and 1989. Associations between smoking and functional ability were examined using multiple...

  18. Radiation hazards and their effects

    International Nuclear Information System (INIS)

    Lunu, Shyam; Kumar, Hemant; Joshi, Pankaj Kumar; Songara, Venkteshwer

    2012-01-01

    Radiation can be classified into ionizing radiation and non-ionizing radiation, based on whether it is capable of ionizing atoms and breaking chemical bonds. Ultraviolet and higher frequency such as X-rays, gamma rays are ionizing. These pose their own special hazards. Non ionizing radiation is associated with two major potential hazards. i.e. electrical and biological. Additionally includes electric current caused by radiation can generate sparks and create a fire or explosive hazards. Strong radiation can induce current capable of delivering an electric shock. Extremely high power electromagnetic radiation can cause electric currents strong enough to create sparks when an induced voltage exceeds the breakdown voltage of surrounding mediums. A 2009 study at the University of Basal in Switzerland found that intermitted exposure of human cells to a 50 Hz electromagnetic field at a flux density of 10 Gy induced a slight but significant increase of DNA fragmentation in the comet assay. Mobile phones radiation and health concerns have been raised, especially following the enormous increase in the use of wireless mobile telephony throughout the world. Mobile phones use electromagnetic radiation in the microwaves range and some believes this may be harmful to human health. (author)

  19. Surgical treatment of delayed radiation effects in the skin and its indication

    International Nuclear Information System (INIS)

    Tilkorn, H.; Drepper, H.

    1987-01-01

    Since 1960 a total of 1200 patients with skin disease as delayed radiation effects were treated at the Hornheide special clinic, 40% of whom received plastic surgery. This requires knowledge of the type of radiation applied and when it was applied, additional harmful influences, exposure, differentiation in cases of ulcers between primary, cumulative, and combination effect, early radiation effects, and late radiation effects. Secondary factors leading possibly to necrosis may be: recidivation of the primary tumours, benign or malignant neoplasms, traumatic injuries such as injections, sampling, tight clothing, chemical factors like therapeuticals for local application, allergies, infections of the skin with bacteria or fungi, osteomyelitis, non-infections skin disease, and internal disease. A precondition for successful dermatological and surgical treatment are a careful review of the previous case history and exact diagnosis. Some clinical cases serve to illustrate the theoretical explanations and point out possibilities for surgical treatment. (TRV) [de

  20. The effect of single and repeated ultraviolet radiation on the anterior segment of the rabbit eye

    OpenAIRE

    Fris, Miroslav

    2008-01-01

    Over the last two decades, depletion of stratospheric ozone has increased the flux of ultraviolet radiation (UVR) at the surface of the earth and the cumulative effect of UVR has become an important aspect of UV-induced eye damage. Epidemiological studies generally assess the chronic, low dose UVR exposure conditions while the laboratory animal experiments usually examine the acute response to high dose exposures. Thus, the study conditions are dissimilar and we are not free to assume that th...

  1. Effects of the hydraulic conductivity of the matrix/macropore interface on cumulative infiltrations into dual-permeability media

    Science.gov (United States)

    Lassabatere, L.; Peyrard, X.; Angulo-Jaramillo, R.; Simunek, J.

    2009-12-01

    Modeling of water infiltration into the vadose zone is important for better understanding of movement of water-transported contaminants. There is a great need to take into account the soil heterogeneity and, in particular, the presence of macropores or cracks that could generate preferential flow. Several mathematical models have been proposed to describe unsaturated flow through heterogeneous soils. The dual-permeability model (referred to as the 2K model) assumes that flow is governed by Richards equation in both porous regions (matrix and macropores). Water can be exchanged between the two regions following a first-order rate law. Although several studies have dealt with such modeling, no study has evaluated the influence of the hydraulic conductivity of the matrix/macropore interface on water cumulative infiltration. And this is the focus of this study. An analytical scaling method reveals the role of the following main parameters for given boundary and initial conditions: the saturated hydraulic conductivity ratio (R_Ks), the water pressure scale parameter ratio (R_hg), the saturated volumetric water content ratio (R_θs), and the shape parameters of the water retention and hydraulic conductivity functions. The last essential parameter is related to the interfacial hydraulic conductivity (Ka) between the macropore and matrix regions. The scaled 2K flow equations were solved using HYDRUS-1D 4.09 for the specific case of water infiltrating into an initially uniform soil profile and a zero pressure head at the soil surface. A sensitivity of water infiltration was studied for different sets of scale parameters (R_Ks, R_hg, R_θs, and shape parameters) and the scaled interfacial conductivity (Ka). Numerical results illustrate two extreme behaviors. When the interfacial conductivity is zero (i.e., no water exchange), water infiltrates separately into matrix and macropore regions, producing a much deeper moisture front in the macropore domain. In the opposite case

  2. Some characteristics and effects of natural radiation

    International Nuclear Information System (INIS)

    Mc Laughlin, J.P.

    2015-01-01

    Since life first appeared on the Earth, it has, in all its subsequent evolved forms including human, been exposed to natural radiation in the environment both from terrestrial and extra-terrestrial sources. Being an environmental mutagen, ionising natural radiation may have played a role of some significance in the evolution of early life forms on Earth. It has been estimated by United Nations Scientific Committee on the Effects of Atomic Radiation that at the present time, exposure to natural radiation globally results in an annual average individual effective dose of about 2.4 mSv. This represents about 80 % of the total dose from all sources. The three most important components of natural radiation exposure are cosmic radiation, terrestrial radioactivity and indoor radon. Each of these components exhibits both geographical and temporal variabilities with indoor radon exposure being the most variable and also the largest contributor to dose for most people. In this account, an overview is given of the characteristics of the main components of the natural radiation environment and some of their effects on humans. In the case of cosmic radiation, these range from radiation doses to aircrew and astronauts to the controversial topic of its possible effect on climate change. In the case of terrestrial natural radiation, accounts are given of a number of human exposure scenarios. (author)

  3. Radiation effects in ice: New results

    International Nuclear Information System (INIS)

    Baragiola, R.A.; Fama, M.; Loeffler, M.J.; Raut, U.; Shi, J.

    2008-01-01

    Studies of radiation effects in ice are motivated by intrinsic interest and by applications in astronomy. Here we report on new and recent results on radiation effects induced by energetic ions in ice: amorphization of crystalline ice, compaction of microporous amorphous ice, electrostatic charging and dielectric breakdown and correlated structural/chemical changes in the irradiation of water-ammonia ices

  4. Radiation effects of ion beams on polymers

    International Nuclear Information System (INIS)

    Tagawa, Seiichi

    1993-01-01

    Recent progress in the radiation effects of ion beams on polymers are reviewed briefly. Our recent work on the radiation effects of ion beams on polystyrene thin films on silicon wafers and time resolved emission studies on polymers are described. (orig.)

  5. The effects of cumulative risks and promotive factors on urban adolescent alcohol and other drug use: a longitudinal study of resiliency.

    Science.gov (United States)

    Ostaszewski, Krzysztof; Zimmerman, Marc A

    2006-12-01

    Resiliency theory provides a conceptual framework for studying why some youth exposed to risk factors do not develop the negative behaviors they predict. The purpose of this study was to test compensatory and protective models of resiliency in a longitudinal sample of urban adolescents (80% African American). The data were from Years 1 (9th grade) and 4 (12th grade). The study examined effects of cumulative risk and promotive factors on adolescent polydrug use including alcohol, tobacco and marijuana. Cumulative measures of risk/promotive factors represented individual characteristics, peer influence, and parental/familial influences. After controlling for demographics, results of multiple regression of polydrug use support the compensatory model of resiliency both cross-sectionally and longitudinally. Promotive factors were also found to have compensatory effects on change in adolescent polydrug use. The protective model of resiliency evidenced cross-sectionally was not supported in longitudinal analysis. The findings support resiliency theory and the use of cumulative risk/promotive measures in resiliency research. Implications focused on utilizing multiple assets and resources in prevention programming are discussed.

  6. Radiobiologic effects at low radiation levels

    International Nuclear Information System (INIS)

    Casarett, G.W.

    1975-01-01

    Data are reviewed on the effects of low radiation doses on mammals. Data from the 1972 report on the Biological Effects of Ionizing Radiation issued by the Advisory Committee of the National Academy of Sciences and National Research Council are discussed. It was concluded that there are certain radiosensitive systems in which low doses of radiation may cause degenerative effects, including gametogenic epithelium, lens of the eye, and developing embryos. Despite extensive investigation of genetic effects, including chromosomal effects, neither the amount of change that will be caused by very low levels of irradiation nor the degree of associated detriment is known

  7. Physics of intense, high energy radiation effects.

    Energy Technology Data Exchange (ETDEWEB)

    Hjalmarson, Harold Paul; Hartman, E. Frederick; Magyar, Rudolph J.; Crozier, Paul Stewart

    2011-02-01

    This document summarizes the work done in our three-year LDRD project titled 'Physics of Intense, High Energy Radiation Effects.' This LDRD is focused on electrical effects of ionizing radiation at high dose-rates. One major thrust throughout the project has been the radiation-induced conductivity (RIC) produced by the ionizing radiation. Another important consideration has been the electrical effect of dose-enhanced radiation. This transient effect can produce an electromagnetic pulse (EMP). The unifying theme of the project has been the dielectric function. This quantity contains much of the physics covered in this project. For example, the work on transient electrical effects in radiation-induced conductivity (RIC) has been a key focus for the work on the EMP effects. This physics in contained in the dielectric function, which can also be expressed as a conductivity. The transient defects created during a radiation event are also contained, in principle. The energy loss lead the hot electrons and holes is given by the stopping power of ionizing radiation. This information is given by the inverse dielectric function. Finally, the short time atomistic phenomena caused by ionizing radiation can also be considered to be contained within the dielectric function. During the LDRD, meetings about the work were held every week. These discussions involved theorists, experimentalists and engineers. These discussions branched out into the work done in other projects. For example, the work on EMP effects had influence on another project focused on such phenomena in gases. Furthermore, the physics of radiation detectors and radiation dosimeters was often discussed, and these discussions had impact on related projects. Some LDRD-related documents are now stored on a sharepoint site (https://sharepoint.sandia.gov/sites/LDRD-REMS/default.aspx). In the remainder of this document the work is described in catergories but there is much overlap between the atomistic

  8. Physics of intense, high energy radiation effects

    International Nuclear Information System (INIS)

    Hjalmarson, Harold Paul; Hartman, E. Frederick; Magyar, Rudolph J.; Crozier, Paul Stewart

    2011-01-01

    This document summarizes the work done in our three-year LDRD project titled 'Physics of Intense, High Energy Radiation Effects.' This LDRD is focused on electrical effects of ionizing radiation at high dose-rates. One major thrust throughout the project has been the radiation-induced conductivity (RIC) produced by the ionizing radiation. Another important consideration has been the electrical effect of dose-enhanced radiation. This transient effect can produce an electromagnetic pulse (EMP). The unifying theme of the project has been the dielectric function. This quantity contains much of the physics covered in this project. For example, the work on transient electrical effects in radiation-induced conductivity (RIC) has been a key focus for the work on the EMP effects. This physics in contained in the dielectric function, which can also be expressed as a conductivity. The transient defects created during a radiation event are also contained, in principle. The energy loss lead the hot electrons and holes is given by the stopping power of ionizing radiation. This information is given by the inverse dielectric function. Finally, the short time atomistic phenomena caused by ionizing radiation can also be considered to be contained within the dielectric function. During the LDRD, meetings about the work were held every week. These discussions involved theorists, experimentalists and engineers. These discussions branched out into the work done in other projects. For example, the work on EMP effects had influence on another project focused on such phenomena in gases. Furthermore, the physics of radiation detectors and radiation dosimeters was often discussed, and these discussions had impact on related projects. Some LDRD-related documents are now stored on a sharepoint site (https://sharepoint.sandia.gov/sites/LDRD-REMS/default.aspx). In the remainder of this document the work is described in catergories but there is much overlap between the atomistic calculations, the

  9. Radiation Effects on Polymers - XI

    DEFF Research Database (Denmark)

    Ghanem, N. A.; El-Awady, N. I.; Singer, Klaus Albert Julius

    1979-01-01

    With the aim of improving properties of cellulose acetate membranes for reverse osmosis desalination, grafting was performed using high energy electrons. In this paper, the grafting parameters (radiation dose and method, monomer concentration, solvents, chain transfer agent and redox system...

  10. Radiation effects in polycarbonate capacitors

    Directory of Open Access Journals (Sweden)

    Vujisić Miloš

    2009-01-01

    Full Text Available The aim of this paper is to examine the influence of neutron and gamma irradiation on the dissipation factor and capacitance of capacitors with polycarbonate dielectrics. The operation of capacitors subject to extreme conditions, such as the presence of ionizing radiation fields, is of special concern in military industry and space technology. Results obtained show that the exposure to a mixed neutron and gamma radiation field causes a decrease of capacitance, while the loss tangent remains unchanged.

  11. Biological effects of high LET radiations

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Masami [Nagasaki Univ. (Japan). Faculty of Pharmaceutical Sciences

    1997-03-01

    Biological effect of radiation is different by a kind of it greatly. Heavy ions were generally more effective in cell inactivation, chromosome aberration induction, mutation induction and neoplastic cell transformation induction than {gamma}-rays in SHE cells. (author)

  12. Genetic effects of ionizing radiation

    International Nuclear Information System (INIS)

    Myers, D.K.; Childs, J.D.

    1980-01-01

    The genetic material in living organisms is susceptible to damage from a wide variety of causes including radiation exposure. Most of this damage is repaired by the organism; the residual damage and damage which is not correctly repaired can lead to genetic changes such as mutations. In lower organisms, most offspring carry an unaltered copy of the genetic information that was present in the parental organism, most of the genetic changes which do occur are not caused by natural background radiation, and the increase in frequency of genetic changes after irradiation at low-dose rates is directly proportional to total radiation dose. The same principles appear to be valid in mammals and other higher organisms. About 105 out of every 1000 humans born suffer from some genetic or partly-genetic condition requiring medical attention at some time. It has been estimated that approximately 1 person in every 2000 born carry a deleterious genetic mutation that was caused by the continued exposure of many generations of our ancestors to natural background radiation. On the same basis, it is predicted that the incidence of genetic diseases would be increased to 106 per 1000 in the children and grandchildren of radiation workers who were exposed to 1 rem per year commencing at age 18. However, there was no detectable change in the health and fitness of mice whose male ancestors were repeatedly exposed to high radiation doses up to 900 rem per generation. (auth)

  13. Double dose: the cumulative effect of TV viewing at home and in preschool on children's activity patterns and weight status.

    Science.gov (United States)

    Taverno Ross, Sharon; Dowda, Marsha; Saunders, Ruth; Pate, Russell

    2013-05-01

    Little is known about how screen-based sedentary behavior at home and in preschool influences children's health and activity patterns. The current study examined the individual and cumulative influence of TV viewing at home and in preschool on children's physical activity (PA) and weight status. Children (n = 339) attending 16 preschools in South Carolina were grouped into high and low TV groups based on parent report of children's TV viewing at home and director report of TV use/rules in preschool. T-tests and mixed model ANOVAs examined differences in weight status and PA (min/hr) by high and low TV groups. Results revealed that children who were classified as High TV both at home and in pre- school had significantly lower levels of moderate-to-vigorous PA compared with their Low TV counterparts (8.3 (0.3) min/hr vs. 7.6 (0.2) min/hr, p TV groups at home or in preschool when examined individually. These findings demonstrate the importance of total environmental TV exposure on preschooler's PA. Longitudinal and observational research to assess preschoolers' cumulative screen-based sedentary behavior and its relationship with PA and weight status is needed.

  14. Modification of genetic effects of gamma radiation by laser radiation

    International Nuclear Information System (INIS)

    Khotyljova, L.V.; Khokhlova, S.A.; Khokhlov, I.V.

    1988-01-01

    Full text: Mutants obtained by means of ionizing radiation and chemical mutagens often show low viability and productivity that makes their use in plant breeding difficult. Methods reducing the destructive mutagen action on important functions of plant organism and increasing quality and practical value of induced mutants would be interesting. We believe that one method for increasing efficiency of experimental mutagenesis in plants is the application of laser radiation as a modificator of genetic effects of ionizing radiation and chemical mutagens. Combined exposure of wheat seedlings to a gamma radiation dose of 2 kR and to laser radiation with the wave length of 632.8 nm (power density - 20 mVt/cm 2 , exposure - 30 min.) resulted in reducing the chromosomal aberration percentage from 30.5% in the gamma version to 16.3% in the combined treatment version. A radiosensibilizing effect was observed at additional exposure of gamma irradiated wheat seeds to laser light with the wave length of 441.6 nm where chromosomal aberration percentage increased from 22% in the gamma-irradiation version to 31% in the combined treatment version. By laser radiation it is also possible to normalize mitotic cell activity suppressed by gamma irradiation. Additional seedling irradiation with the light of helium-neon laser (632.8 nm) resulted in recovery of mitotic cell activity from 21% to 62% and increasing the average content of DNA per nucleus by 10%. The influence of only laser radiation on plant variability was also studied and it was shown that irradiation of wheat seeds and seedlings with pulsed and continuous laser light of visible spectrum resulted in phenotypically altered forms in M 2 . Their frequencies was dependent upon power density, dose and radiation wave length. Number of altered forms increased in going from long-wave to short-wave spectrum region. In comparing efficiency of different laser types of pulsed and continuous exposure (dose - 180 J/cm 2 ) 2% of altered

  15. Radiation effects on light sources and detectors

    International Nuclear Information System (INIS)

    Barnes, C.E.

    1985-01-01

    The rapidly expanding field of optoelectronics includes a wide variety of both military and non-military applications in which the systems must meet radiation exposure requirements. Herein, we review the work on radiation effects on sources and detectors for such optoelectronic systems. For sources the principal problem is permanent damage-induced light output degradation, while for detectors it is ionizing radiation-induced photocurrents

  16. Bystander Effects of Ionizing Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Little, John B. [Harvard T.H. Chan School of Public Health, Boston, MA (United States). Dept. of Genetics and Complex Diseases

    2017-01-17

    The objectives of this grant renewal are to provide administrative support and travel funds to allow the continued participation of the principal investigator (Dr. John B. Little) as an advisor to research initiated by several research fellows from his laboratory. The actual research will be carried out under the direction of Dr. Hatsumi Nagasawa with the collaboration of Dr. Joel Bedford at the Colorado State University, and by Drs. Edouard Azzam and Sonia de Toledo at the University of Medicine and Dentistry of New Jersey. Dr. Little will advise on the planning of experiments and development of experimental protocols, the analysis of data, and the preparation of manuscripts for publication. The Specific Aims for several of the planned experiments include: 1) to extend studies of the role of recombinational repair in the bystander effect by examining other genes in this pathway and cell lines deficient in excision repair; 2) to continue studies to determine the nature of the damage signal transmitted to bystander cells including the expression of several connexins in the bystander response, and the extent to which the enhanced oxidative metabolism observed in bystander cells may relate to the nature of the transmitted bystander signal; 3) to utilize a genome-wide approach to examine the genetic basis for the hypersensitivity to ionization we have observed in unaffected parents of patients with hereditary retinoblastoma, as well as from a group of apparently normal individuals that show similar radiosensitivity; 4) to complete studies concerning the induction of high frequencies of cells with massive chromosome damage in clonal derivatives of p53 and p21 knockout mouse cell lines; in particular to examine the role of telomere changes in this phenomenon. Overall, the results of these studies should enhance our understanding of the risk of low-dose exposures to ionizing radiation, including human populations to residential radon as well as occupational exposures.

  17. Bystander Effects of Ionizing Radiation

    International Nuclear Information System (INIS)

    Little, John B.

    2017-01-01

    The objectives of this grant renewal are to provide administrative support and travel funds to allow the continued participation of the principal investigator (Dr. John B. Little) as an advisor to research initiated by several research fellows from his laboratory. The actual research will be carried out under the direction of Dr. Hatsumi Nagasawa with the collaboration of Dr. Joel Bedford at the Colorado State University, and by Drs. Edouard Azzam and Sonia de Toledo at the University of Medicine and Dentistry of New Jersey. Dr. Little will advise on the planning of experiments and development of experimental protocols, the analysis of data, and the preparation of manuscripts for publication. The Specific Aims for several of the planned experiments include: 1) to extend studies of the role of recombinational repair in the bystander effect by examining other genes in this pathway and cell lines deficient in excision repair; 2) to continue studies to determine the nature of the damage signal transmitted to bystander cells including the expression of several connexins in the bystander response, and the extent to which the enhanced oxidative metabolism observed in bystander cells may relate to the nature of the transmitted bystander signal; 3) to utilize a genome-wide approach to examine the genetic basis for the hypersensitivity to ionization we have observed in unaffected parents of patients with hereditary retinoblastoma, as well as from a group of apparently normal individuals that show similar radiosensitivity; 4) to complete studies concerning the induction of high frequencies of cells with massive chromosome damage in clonal derivatives of p53 and p21 knockout mouse cell lines; in particular to examine the role of telomere changes in this phenomenon. Overall, the results of these studies should enhance our understanding of the risk of low-dose exposures to ionizing radiation, including human populations to residential radon as well as occupational exposures.

  18. Comparative proteomic analysis of rice after seed ground simulated radiation and spaceflight explains the radiation effects of space environment

    Science.gov (United States)

    Wang, Wei; Shi, Jinming; Liang, Shujian; Lei, Huang; Shenyi, Zhang; Sun, Yeqing

    In previous work, we compared the proteomic profiles of rice plants growing after seed space-flights with ground controls by two-dimensional difference gel electrophoresis (2-D DIGE) and found that the protein expression profiles were changed after seed space environment exposures. Spaceflight represents a complex environmental condition in which several interacting factors such as cosmic radiation, microgravity and space magnetic fields are involved. Rice seed is in the process of dormant of plant development, showing high resistance against stresses, so the highly ionizing radiation (HZE) in space is considered as main factor causing biological effects to seeds. To further investigate the radiation effects of space environment, we performed on-ground simulated HZE particle radiation and compared between the proteomes of seed irra-diated plants and seed spaceflight (20th recoverable satellite) plants from the same rice variety. Space ionization shows low-dose but high energy particle effects, for searching the particle effects, ground radiations with the same low-dose (2mGy) but different liner energy transfer (LET) values (13.3KeV/µm-C, 30KeV/µm-C, 31KeV/µm-Ne, 62.2KeV/µm-C, 500Kev/µm-Fe) were performed; using 2-D DIGE coupled with clustering and principle component analysis (PCA) for data process and comparison, we found that the holistic protein expression patterns of plants irradiated by LET-62.2KeV/µm carbon particles were most similar to spaceflight. In addition, although space environment presents a low-dose radiation (0.177 mGy/day on the satellite), the equivalent simulated radiation dose effects should still be evaluated: radiations of LET-62.2KeV/µm carbon particles with different cumulative doses (2mGy, 20mGy, 200mGy, 2000mGy) were further carried out and resulted that the 2mGy radiation still shared most similar proteomic profiles with spaceflight, confirming the low-dose effects of space radiation. Therefore, in the protein expression level

  19. Chernobyl health effects: radiation or stress?

    International Nuclear Information System (INIS)

    Grinkhal', G.

    1996-01-01

    Consideration is given to results of wide-scale examination of human population, subjected to the effect of radiation in result of Chernobyl accident. The examined contingents consisted of liquidators, evacuated from 30-km zone, people still living in contamination territories, children of irradiated parents and children, who received large radiation doses. High levels of respiratory system diseases, digestive system diseases, cardiovascular diseases and nervous system diseases were revealed for these people. It was revealed that stress, socio-economic and chemical factors played sufficient role in disease incidence. It is shown that fair of radiation may damage more, than radiation itself

  20. Late effects of radiation: host factors

    International Nuclear Information System (INIS)

    Fry, R.J.M.; Storer, J.B.

    1983-01-01

    The paper discusses the influence of host factors on radiation late effects and in particular cancer. Radiation induces cellular changes that result in initiated cells with a potential to become cancers. The expression of the initiated cells as tumors is influenced, if not determined, by both tissue and systemic factors that are sex-, age-, and species-dependent

  1. Biological radiation effects and radioprotection standards

    International Nuclear Information System (INIS)

    Clerc, H.

    1991-03-01

    In this report, after recalling the mode of action of ionizing radiations, the notions of dose, dose equivalents and the values of natural irradiation, the author describes the biological radiation effects. Then he presents the ICRP recommendations and their applications to the french radioprotection system

  2. Radiation effects on Fischer-Tropsch syntheses

    International Nuclear Information System (INIS)

    Hatada, M.; Matsuda, K.

    1977-01-01

    Radiation effects on Fischer-Tropsch synthesis has been examined using high dose rate electron beams and Fe-Cu-diatomaceous earth catalyst. Yields of saturated hydrocarbons were found to increase by irradiation, but the yields of these compounds were decreased by raising reaction temperature without irradiation, suggesting the presence of radiation chemical process in catalytic reactions. (author)

  3. Radiation effects in charge coupled devices

    International Nuclear Information System (INIS)

    Williams, R.A.; Nelson, R.D.

    1975-01-01

    Charge coupled devices (CCD s) exhibit a number of advantages (low cost, low power, high bit density) in their several applications (serial memories, imagers, digital filters); however, fairly elementary theoretical considerations indicate that they will be very vulnerable to permanent radiation damage, by both neutrons and ionizing radiation, and to transient upset by pulsed ionizing radiation. Although studies of permanent ionizing-radiation damage in CCD's have been reported, little information has been published concerning their overall nuclear radiation vulnerability. This paper presents a fairly comprehensive experimental study of radiation effects in a 256-cell surface-channel, CCD shift-register. A limited amount of similar work is also presented for a 128-cell surface-channel device and a 130 cell peristaltic CCD shift register. The radiation effects phenomena discussed herein, include transient-ionizing-radiation responses, permanent ionizing- radiation damage to transfer efficiency, charge-carrying capacity and input transfer gate bias, and neutron damage to storage time--determined from dark current and charge-up time measurements

  4. Coherence effects in radiative scattering

    International Nuclear Information System (INIS)

    Knoll, J.; Lenk, R.

    1993-03-01

    The bremsstrahl-production of photons in dense matter is reinvestigated using the example of an exactly solvable quantum mechanical model in one space dimension. Coherence phenomena between successive radiative scatterings among the constituents lead to a modification of the production cross section in the medium relative to the incoherent quasi-free prescription used in kinetic models. Analytic expressions for the correction factor have been derived comparing the quantum rates with the corresponding incoherent quasi-free rates. The result has implications for the kinetic description of all kinds of radiative processes in nucleus-nucleus collisions, both on the level of hadron and parton dynamics. (orig.)

  5. Comparison of the immediate, residual, and cumulative antibacterial effects of Novaderm R,* Novascrub R,* Betadine Surgical Scrub, Hibiclens, and liquid soap.

    Science.gov (United States)

    Faoagali, J; Fong, J; George, N; Mahoney, P; O'Rourke, V

    1995-12-01

    Triclosan (Irgasan), an antibacterial active against staphylococci and coliform bacteria, has been formulated for use as a handwash. There has been only one previous report of the use of the glove juice test to determine the immediate, residual, and cumulative effects of a 1% triclosan-based handwash product. There have been no previous studies on the use of 1% triclosan combined with povidone-iodine (PI) in a handwash product. The glove juice technique was used to document and compare the immediate, 3-hour residual, and 5-day cumulative effects on the mean log10 bacterial counts of 1% triclosan-based handwash product and 1% triclosan with 5% PI. A standardized surgical handwashing technique was used before sample collection. These results and the identity and type of the aerobic bacteria cultured from the samples were compared with the results of standardized washing and glove juice sampling with 4% weight/volume chlorhexidine gluconate (CHG), 7.5% PI, and a nonantimicrobial liquid soap. All five tested products showed significant log10 reduction from baseline on day 1, hour 0 (p 0.05). There was a significant difference between 1% triclosan and the liquid soap when they were each compared with 4% CHG, 7.5% PI, and 1% triclosan with 5% PI. There was no statistically significant difference between the 1% triclosan product and the liquid soap (p > 0.20). All products were effective at reducing the immediate bacterial count from the baseline level. All formulations except the liquid soap showed significant cumulative effect (p liquid soap and 1% triclosan (p > 0.05). Both products differed significantly (p < 0.05) from the CHG, PI, and triclosan with PI. CHG, PI, and triclosan with PI showed effects significantly different from each other (p < 0.05). Triclosan combined with PI resulted in the prevention of bacterial regrowth at 3 hours such as occurred when PI alone was used. Triclosan-containing products have a small cumulative effect, although not as great as that

  6. Physics of radiation effects in crystals

    CERN Document Server

    Johnson, RA

    1986-01-01

    ``Physics of Radiation Effects in Crystals'' is presented in two parts. The first part covers the general background and theory of radiation effects in crystals, including the theory describing the generation of crystal lattice defects by radiation, the kinetic approach to the study of the disposition of these defects and the effects of the diffusion of these defects on alloy compositions and phases. Specific problems of current interest are treated in the second part and include anisotropic dimensional changes in x-uranium, zirconium and graphite, acceleration of thermal creep in reactor ma

  7. Effects of radiation on scintillating fiber performance

    International Nuclear Information System (INIS)

    Bauer, M.L.; Cohn, H.; Efremenko, Yu.; Gordeev, A.; Kamyshkov, Yu.; Onopienko, D.; Savin, S.; Shmakov, K.; Tarkovsky, E.; Young, K.G.; Carey, R.; Rothman, M.; Sulak, L.; Worstell, W.; Parr, H.

    1992-01-01

    Continued rapid improvements in formulations for scintillating fibers require the ability to parameterize and predict effects of radiation on detector performance. Experimental techniques necessary to obtain needed information and calculational procedures used in performing predications for hadron scintillating fiber calorimetry in the Superconducting Supercollider environment are described. The experimental techniques involve control of the testing environment, consideration of dose rate effects, and other factors. These calculations involve the behavior of particle showers in the detector, expected levels of radiation, and parameterization of the radiation effects. A summary of significant work is also presented

  8. Effects of radiation on scintillating fiber performance

    International Nuclear Information System (INIS)

    Young, K.G.; Bauer, M.L.; Cohn, H.; Efremenko, Yu.; Gordeev, A.; Kamyshkov, Yu.; Onopienko, D.; Savin, S.; Shmakov, K.; Tarkovsky, E.; Carey, R.; Rothman, M.; Sulak, L.; Worstell, W.; Paar, H.

    1993-01-01

    Continued rapid improvements in formulations for scintillating fibers require the ability to parameterize and predict effects of radiation on detector performance. Experimental techniques necessary to obtain desired information and calculational procedures used in performing predictions for hadron scintillating fiber calorimetry in the Superconducting Supercollider environment are described. The experimental techniques involve control of the testing environment, consideration of dose rate effects, and other factors. The calculations involve the behavior of particle showers in the detector, expected levels of radiation, and parameterization of the radiation effects. A summary of significant work is also presented

  9. Characteristics of natural background external radiation and effective dose equivalent

    International Nuclear Information System (INIS)

    Fujimoto, Kenzo

    1989-01-01

    The two sources of natural radiation - cosmic rays and primordial radionuclides - are described. The factors affecting radiation doses received from natural radiation and the calculation of effective dose equivalent due to natural radiation are discussed. 10 figs., 3 tabs

  10. Overview of radiation effects research in photonics

    Science.gov (United States)

    Webb, Robert C.; Cohn, Lewis M.; Taylor, Edward W.; Greenwell, Roger A.

    1995-05-01

    A brief overview of ongoing radiation effects research in photonics is presented focusing on integrated optic and acousto-optic components. A short summary of radiation-induced effects in electro-optic modulators, detector arrays, and other photonic technologies is presented along with extensive references. The coordinated radiation effects studies among researchers within the Tri-Service Organizations and international experimental teams are beginning to demonstrate consistent measurements of radiation-induced effects in photonic components and confirming earlier reported data. This paper will present an overview of these coordinated investigations and focus on key research being conducted with the AFMC Phillips Laboratory, Naval Research Laboratory, Defence Nuclear Agency, NATO Nuclear Effects Task Group, and the Tri-Service Photonics Coordinating Committee.

  11. Effects of small radiation doses

    International Nuclear Information System (INIS)

    Fuchs, G.

    1986-01-01

    The term 'small radiation dosis' means doses of about (1 rem), fractions of one rem as well as doses of a few rem. Doses like these are encountered in various practical fields, e.g. in X-ray diagnosis, in the environment and in radiation protection rules. The knowledge about small doses is derived from the same two forces, on which the radiobiology of human beings nearly is based: interpretation of the Hiroshima and Nagasaki data, as well as the experience from radiotherapy. Careful interpretation of Hiroshima dates do not provide any evidence that small doses can induce cancer, fetal malformations or genetic damage. Yet in radiotherapy of various diseases, e.g. inflammations, doses of about 1 Gy (100 rad) do no harm to the patients. According to a widespread hypothesis even very small doses may induce some types of radiation damage ('no threshold'). Nevertheless an alternative view is justified. At present no decision can be made between these two alternatives, but the usefullness of radiology is definitely better established than any damage calculated by theories or extrapolations. Based on experience any exaggerated fear of radiations can be met. (author)

  12. High background radiation area: an important source of exploring the health effects of low dose ionizing radiation

    International Nuclear Information System (INIS)

    Wei Luxin

    1997-01-01

    Objective: For obtaining more effective data from epidemiological investigation in high background radiation areas, it is necessary to analyze the advantages, disadvantages, weak points and problems of this kind of radiation research. Methods: For epidemiological investigation of population health effects of high background radiation, the author selected high background radiation areas of Yangjiang (HBRA) and a nearby control area (CA) as an instance for analysis. The investigation included classification of dose groups, comparison of the confounding factors in the incidence of mutation related diseases, cancer mortalities and the frequencies of chromosomal aberrations between HBRA and CA. This research program has become a China-Japan cooperative research since 1991. Results: The confounding factors above-mentioned were comparable between HBRA and CA, and within the dose groups in HBRA, based on a systematic study for many years. The frequencies of chromosomal aberrations increased with the increase of cumulative dose, but not for children around or below 10 years of age. The relative risks (RR) of total and site-specific cancer mortalities for HBRA were lower or around 1.00, compared with CA. The incidence of hereditary diseases and congenital deformities in HBRA were in normal range. The results were interpreted preliminarily by the modified 'dual radiation action' theory and the 'benefit-detriment competition' hypothesis. Conclusions: The author emphasizes the necessity for continuing epidemiological research in HBRA, especially for international cooperation. He also emphasizes the importance of combination of epidemiology and radiobiology

  13. Effect of radiation processing on meat tenderisation

    International Nuclear Information System (INIS)

    Kanatt, Sweetie R.; Chawla, S.P.; Sharma, Arun

    2015-01-01

    The effect of radiation processing (0, 2.5, 5 and 10 kGy) on the tenderness of three types of popularly consumed meat in India namely chicken, lamb and buffalo was investigated. In irradiated meat samples dose dependant reduction in water holding capacity, cooking yield and shear force was observed. Reduction in shear force upon radiation processing was more pronounced in buffalo meat. Protein and collagen solubility as well as TCA soluble protein content increased on irradiation. Radiation processing of meat samples resulted in some change in colour of meat. Results suggested that irradiation leads to dose dependant tenderization of meat. Radiation processing of meat at a dose of 2.5 kGy improved its texture and had acceptable odour. - Highlights: • Effect of radiation processing on tenderness of three meat systems was evaluated. • Dose dependant reduction in shear force seen in buffalo meat. • Collagen solubility increased with irradiation

  14. Effects of gamma radiation in tomato seeds

    Energy Technology Data Exchange (ETDEWEB)

    Wiendl, Toni A.; Wiendl, Fritz W.; Franco, Suely S.H.; Franco, Jose G.; Althur, Valter, E-mail: tawiendl@hotmail.com, E-mail: gilmita@uol.com.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Arthur, Paula B., E-mail: arthur@cena.usp.br [Centro de Energia Nuclear na Agricultura (CENA/USP), Piracicaba, SP (Brazil)

    2013-07-01

    Tomato dry seeds of the hybrid 'Gladiador' F1 were exposed to low doses of gamma radiation from Co-60 source at 0,509 kGy tax rate in order to study stimulation effects of radiation on germination and plant growth. Eight treatments radiation doses were applied as follows: 0 (control); 2,5; 5,0; 7,5; 10,0; 12,5; 15,0; 20,0 Gy. Seed germination as well as green fruits number, harvested fruit number, fruit weight and total production were assessed to identify occurrence of stimulation. Tomato seeds and plants were handled as for usual tomato production in Brazil. Low doses of gamma radiation treatment in the seeds stimulate germination and substantially increase fruit number and total production up to 86% at 10 Gy dose. There are evidences that the use of low doses of gamma radiation can stimulate germination and plant production thus, showing hormetic effects. (author)

  15. Radiation effect on rocket engine performance

    Science.gov (United States)

    Chiu, Huei-Huang; Kross, K. W.; Krebsbach, A. N.

    1990-01-01

    Critical problem areas involving the effect of radiation on the combustion of bipropellants are addressed by formulating a universal scaling law in combination with a radiation-enhanced vaporization combustion model. Numerical algorithms are developed and data pertaining to the Variable Thrust Engine (VTE) and the Space Shuttle Main Engine (SSME) are used to conduct parametric sensitivity studies to predict the principal intercoupling effects of radiation. The analysis reveals that low-enthalpy engines, such as the VTE, are vulnerable to a substantial performance setback due to radiative loss, whereas the performance of high-enthalpy engines such as the SSME are hardly affected over a broad range of engine operation. Combustion enhancement by radiative heating of the propellant has a significant impact on propellants with high absorptivity.

  16. Effects of gamma radiation in tomato seeds

    International Nuclear Information System (INIS)

    Wiendl, Toni A.; Wiendl, Fritz W.; Franco, Suely S.H.; Franco, Jose G.; Althur, Valter; Arthur, Paula B.

    2013-01-01

    Tomato dry seeds of the hybrid 'Gladiador' F1 were exposed to low doses of gamma radiation from Co-60 source at 0,509 kGy tax rate in order to study stimulation effects of radiation on germination and plant growth. Eight treatments radiation doses were applied as follows: 0 (control); 2,5; 5,0; 7,5; 10,0; 12,5; 15,0; 20,0 Gy. Seed germination as well as green fruits number, harvested fruit number, fruit weight and total production were assessed to identify occurrence of stimulation. Tomato seeds and plants were handled as for usual tomato production in Brazil. Low doses of gamma radiation treatment in the seeds stimulate germination and substantially increase fruit number and total production up to 86% at 10 Gy dose. There are evidences that the use of low doses of gamma radiation can stimulate germination and plant production thus, showing hormetic effects. (author)

  17. Biological effects of proton radiation: an update

    International Nuclear Information System (INIS)

    Girdhani, S.; Hlatky, L.; Sachs, R.

    2015-01-01

    Proton radiation provides significant dosimetric advantages when compared with gamma radiation due to its superior energy deposition characteristics. Although the physical aspects of proton radiobiology are well understood, biological and clinical endpoints are understudied. The current practice to assume the relative biological effectiveness of low linear energy transfer (LET) protons to be a generic value of about 1.1 relative to photons likely obscures important unrecognised differentials in biological response between these radiation qualities. A deeper understanding of the biological properties induced by proton radiation would have both radiobiological and clinical impact. This article briefly points to some of the literature pertinent to the effects of protons on tissue-level processes that modify disease progression, such as angiogenesis, cell invasion and cancer metastasis. Recent findings hint that proton radiation may, in addition to offering improved radio-therapeutic targeting, be a means to provide a new dimension for increasing therapeutic benefits for patients by manipulating these tissue-level processes. (authors)

  18. The effects of ionizing radiation on man

    International Nuclear Information System (INIS)

    Watson, G.M.

    1975-08-01

    This paper describes the major effects of ionizing radiation on man and the relationship between such effects and radiation dose, with the conclusion that standards of radiological safety must be based on the carcinogenetic and mutagenic properties of ionizing radiation. Man is exposed to radiation from natural sources and from man-made sources. Exposure from the latter should be regulated but, since there is little observational or experimental evidence for predicting the effects of the very small doses likely to be required for adequate standards of safety, it is necessary to infer them from what is seen at high doses. Because the formal relationship between dose and effect is not fully understood, simplifying assumptions are necessary to estimate the effects of low doses. Two such assumptions are conventionally used; that there is a linear relationship between dose and effect at all levels of dose, and that the rate at which a dose of radiation is given does not alter the magnitude of the effect. These assumptions are thought to be conservative, that is they will not lead to an underestimation of the effects of small radiation doses although they may give an over-estimate. (author)

  19. Fast Neutron Radiation Effects on Bacillus Subtili

    International Nuclear Information System (INIS)

    Chen Xiaoming; Zhang Jianguo; Chu Shijin; Ren Zhenglong; Zheng Chun; Yang Chengde; Tan Bisheng

    2009-01-01

    To examine the sterilizing effect and mechanism of neutron radiation, Bacillus subtilis var. niger. strain (ATCC 9372) spores were irradiated with the fast neutron from the Chinese fast burst reactor II(CFBR-II). The plate-count results indicated that the D 10 value was 384.6 Gy with a neutron radiation dose rate of 7.4 Gy/min. The rudimental catalase activity of the spores declined obviously with the increase in the radiation dose. Meanwhile, under the scanning electron microscope, no visible influence of the neutron radiation on the spore configuration was detected even if the dose was increased to 4 kGy. The content and distribution of DNA double-strand breaks induced by neutron radiation at different doses were measured and quantified by pulsed-field gel electrophoresis (PFGE). Further analysis of the DNA release percentage (PR), the DNA breakage level (L), and the average molecular weight, indicated that DNA fragments were obviously distributed around the 5 kb regions at different radiation doses, which suggests that some points in the DNA molecule were sensitive to neutron radiation. Both PR and L varied regularly to some extent with the increase in radiation dose. Thus neutron radiation has a high sterilization power, and can induce falling enzyme activity and DNA breakage in Bacillus subtilis spores

  20. Radiative effects of global MODIS cloud regimes

    Science.gov (United States)

    Oreopoulos, Lazaros; Cho, Nayeong; Lee, Dongmin; Kato, Seiji

    2018-01-01

    We update previously published MODIS global cloud regimes (CRs) using the latest MODIS cloud retrievals in the Collection 6 dataset. We implement a slightly different derivation method, investigate the composition of the regimes, and then proceed to examine several aspects of CR radiative appearance with the aid of various radiative flux datasets. Our results clearly show the CRs are radiatively distinct in terms of shortwave, longwave and their combined (total) cloud radiative effect. We show that we can clearly distinguish regimes based on whether they radiatively cool or warm the atmosphere, and thanks to radiative heating profiles to discern the vertical distribution of cooling and warming. Terra and Aqua comparisons provide information about the degree to which morning and afternoon occurrences of regimes affect the symmetry of CR radiative contribution. We examine how the radiative discrepancies among multiple irradiance datasets suffering from imperfect spatiotemporal matching depend on CR, and whether they are therefore related to the complexity of cloud structure, its interpretation by different observational systems, and its subsequent representation in radiative transfer calculations. PMID:29619289

  1. Radiative Effects of Global MODIS Cloud Regimes

    Science.gov (United States)

    Oraiopoulos, Lazaros; Cho, Nayeong; Lee, Dong Min; Kato, Seiji

    2016-01-01

    We update previously published MODIS global cloud regimes (CRs) using the latest MODIS cloud retrievals in the Collection 6 dataset. We implement a slightly different derivation method, investigate the composition of the regimes, and then proceed to examine several aspects of CR radiative appearance with the aid of various radiative flux datasets. Our results clearly show the CRs are radiatively distinct in terms of shortwave, longwave and their combined (total) cloud radiative effect. We show that we can clearly distinguish regimes based on whether they radiatively cool or warm the atmosphere, and thanks to radiative heating profiles to discern the vertical distribution of cooling and warming. Terra and Aqua comparisons provide information about the degree to which morning and afternoon occurrences of regimes affect the symmetry of CR radiative contribution. We examine how the radiative discrepancies among multiple irradiance datasets suffering from imperfect spatiotemporal matching depend on CR, and whether they are therefore related to the complexity of cloud structure, its interpretation by different observational systems, and its subsequent representation in radiative transfer calculations.

  2. Predicted solar cell edge radiation effects

    International Nuclear Information System (INIS)

    Gates, M.T.

    1993-01-01

    The Advanced Solar Cell Orbital Test (ASCOT) will test six types of solar cells in a high energy proton environment. During the design of the experiment a question was raised about the effects of proton radiation incident on the edge of the solar cells and whether edge radiation shielding was required. Historical geosynchronous data indicated that edge radiation damage is not detectable over the normal end of life solar cell degradation; however because the ASCOT radiation environment has a much higher and more energetic fluence of protons, considerably more edge damage is expected. A computer analysis of the problem was made by modeling the expected radiation damage at the cell edge and using a network model of small interconnected solar cells to predict degradation in the cell's electrical output. The model indicated that the deepest penetration of edge radiation was at the top of the cell near the junction where the protons have access to the cell through the low density cell/cover adhesive layer. The network model indicated that the cells could tolerate high fluences at their edge as long as there was high electrical resistance between the edge radiated region and the contact system on top of the cell. The predicted edge radiation related loss was less than 2% of maximum power for GaAs/Ge solar cells. As a result, no edge radiation protection was used for ASCOT

  3. The Effects of Ionizing Radiation on Mammalian Cells.

    Science.gov (United States)

    Biaglow, John E.

    1981-01-01

    Discusses the effects of radiation on dividing cells and factors influencing these effects; also briefly reviews the radical mechanism for radiation damage. Emphasizes the importance of oxygen in radiation effects. (CS)

  4. Internal friction, microstructure, and radiation effects

    International Nuclear Information System (INIS)

    Wechsler, M.S.; Sommer, W.F.; Davidson, D.R.

    1984-01-01

    A brief review is given of internal friction relaxation peaks and background internal friction. The microstructural origin of the internal friction is discussed. Particular emphasis is placed on radiation effects

  5. Effects of solar radiation on glass

    Science.gov (United States)

    Tucker, Dennis S.; Kinser, Donald L.

    1991-01-01

    The effects of solar radiation of selected glasses are reported. Optical property degradation is studied using UV-Vis spectrophotometry. Strength changes are measured using a concentric ring bend test. Direct fracture toughness measurements using an indentation test are planned.

  6. Decomposition of radiational effects of model feedbacks

    International Nuclear Information System (INIS)

    Ellsaesser, H.W.; MacCracken, M.C.; Potter, G.L.; Mitchell, C.S.

    1981-08-01

    Three separate doubled CO 2 experiments with the statistical dynamic model are used to illustrate efforts to study the climate dynamics, feedbacks, and interrelationships of meteorological parameters by decomposing and isolating their individual effects on radiation transport

  7. Sterilizing radiation effects on selected polymers

    International Nuclear Information System (INIS)

    Skiens, W.E.

    1979-03-01

    The mechanism of radiation effects and their industrial applications are discussed for the following classes of polymers: thermoplastics, thermosets, elastomers, films and fibers, and adhesives/coatings/potting compounds. 35 references, 3 tables

  8. Radiobiology: Biologic effects of ionizing radiations

    International Nuclear Information System (INIS)

    Held, K.D.

    1987-01-01

    The biologic effects after exposure to ionizing radiation, such as cell death or tissue injury, result from a chain of complex physical, chemical, metabolic, and histologic events. The time scale of these radiation actions spans many orders of magnitude. The physical absorption of ionizing radiation occurs in about 10 -18 s, while late carcinogenic and genetic effects are expressed years or even generations later. Collectively, these effects form the science of radiobiology. Many of the concepts discussed in this chapter have been developed through the study of effects generated in tissues by external radiation sources, but they apply generally and often specifically to internally distributed radiopharmaceuticals which form the central topic of this book

  9. Genetic effects of ionizing radiations in Eucaryocytes

    International Nuclear Information System (INIS)

    Jullien, Pierre

    1976-01-01

    The litterature on the genetic effects of ionizing radiations is reviewed, especially as concerns specific loci or chromosome mutations. Extrapolation from one species to another is considered as well as extra-nuclear mutations [fr

  10. The effect of ionizing radiation on cyanophyta

    International Nuclear Information System (INIS)

    Kondrat'eva, N.V.; Shevchenko, T.F.; Golubkova, M.G.

    1989-01-01

    Publication data on the effect of ionizing radiation on cyanophyta are generalized. The conclusion about the presence of premises for forming cyanophyta radiobiology as special direction of procaryotic algae investigation is made

  11. [Effects of radiation exposure on human body].

    Science.gov (United States)

    Kamiya, Kenji; Sasatani, Megumi

    2012-03-01

    There are two types of radiation health effect; acute disorder and late on-set disorder. Acute disorder is a deterministic effect that the symptoms appear by exposure above a threshold. Tissues and cells that compose the human body have different radiation sensitivity respectively, and the symptoms appear in order, from highly radiosensitive tissues. The clinical symptoms of acute disorder begin with a decrease in lymphocytes, and then the symptoms appear such as alopecia, skin erythema, hematopoietic damage, gastrointestinal damage, central nervous system damage with increasing radiation dose. Regarding the late on-set disorder, a predominant health effect is the cancer among the symptoms of such as cancer, non-cancer disease and genetic effect. Cancer and genetic effect are recognized as stochastic effects without the threshold. When radiation dose is equal to or more than 100 mSv, it is observed that the cancer risk by radiation exposure increases linearly with an increase in dose. On the other hand, the risk of developing cancer through low-dose radiation exposure, less 100 mSv, has not yet been clarified scientifically. Although uncertainty still remains regarding low level risk estimation, ICRP propound LNT model and conduct radiation protection in accordance with LNT model in the low-dose and low-dose rate radiation from a position of radiation protection. Meanwhile, the mechanism of radiation damage has been gradually clarified. The initial event of radiation-induced diseases is thought to be the damage to genome such as radiation-induced DNA double-strand breaks. Recently, it is clarified that our cells could recognize genome damage and induce the diverse cell response to maintain genome integrity. This phenomenon is called DNA damage response which induces the cell cycle arrest, DNA repair, apoptosis, cell senescence and so on. These responses act in the direction to maintain genome integrity against genome damage, however, the death of large number of

  12. Effects of radiations on ornamental fish

    International Nuclear Information System (INIS)

    Anita; Kalyankar, Amol D.; Ohlyan, Sunita; Gupta, R.K.

    2012-01-01

    Radiation is a process in which energetic particles or energetic waves travel through a medium or space. There are two distinct types of radiations: ionizing and non-ionizing. Ultraviolet, X-rays, and gamma rays are some examples of radiation. 'Ornamental fish' is designed for aquatic hobbyists and the aquatic industry for several purposes. UV light has two primary uses in fish culture: Controlling green water and disinfecting the water supply. Many proponents of UV disinfection sometimes overlook the additional benefits relating to ornamental fish; those being that cleaner water reduces the stress on the fish by not having to fight off diseases, thus enhancing its immune system and leading to faster growth and more brilliant colors. Ultraviolet sterilizers are often used in aquaria to help control unwanted microorganisms in the water. UV radiation also ensures that exposed pathogens cannot reproduce, thus decreasing the likelihood of a disease outbreak in an aquarium. Despite of these benefits, the ill-effects of radiations cannot be ruled out. Ultraviolet Radiation-induced DNA Damage is seen in the skin of the Platyfish Xiphophorus. Higher radiation doses may cause the gastrointestinal syndrome that leads to defects of the intestinal mucosa barrier with successive contamination of musculature. Exposure to UV radiation can kill the fish and induce sublethal effects in embryos, larvae and adults. The change in skin includes irregularity of skin surface, epidermal oedema, necrosis etc. Irradiation may badly influence the textural attributes of fish muscle. (author)

  13. Effect of ionizing radiations on connective tissue

    International Nuclear Information System (INIS)

    Altman, K.I.; Gerber, G.B.

    1980-01-01

    The effects of ionizing radiations on connective tissue in lung, heart, vasculature, kidney, skin, and skeletal tissues are reviewed. Special emphasis is given to the effect of ionizing radiations on vasculo-connective tissue and fibrotic changes following radiation-induced injury to organs and tissues. In order to put the subject matter in proper prospective, the general biochemistry, physiology, and pathology of connective tissue is reviewed briefly together with the participation of connective tissue in disease. The review closes with an assessment of future problems and an enumeration and discussion of important, as yet unanswered questions

  14. Radiation abuse and its effects

    Energy Technology Data Exchange (ETDEWEB)

    Halm, A

    1976-06-01

    This paper delves into overuse practiced in diagnostic radiography. The conventional attitudes to low-dose irradiation are critically examined, as is the MPD related to individual radiosensitivity. Concern is expressed that a sizeable proportion of radiologists ignore important aspects of the Code of Practice and this attitude is readily emulated in the hospital setting. The author advocates education within the medical profession and the community on the risks involved in radiation abuse and the benefits derived from justified exposures to x rays.

  15. Modifiers of radiation effects in the eye

    Science.gov (United States)

    Kleiman, Norman J.; Stewart, Fiona A.; Hall, Eric J.

    2017-11-01

    World events, including the threat of radiological terrorism and the fear of nuclear accidents, have highlighted an urgent need to develop medical countermeasures to prevent or reduce radiation injury. Similarly, plans for manned spaceflight to a near-Earth asteroid or journey to Mars raise serious concerns about long-term effects of space radiation on human health and the availability of suitable therapeutic interventions. At the same time, the need to protect normal tissue from the deleterious effects of radiotherapy has driven considerable research into the design of effective radioprotectors. For more than 70 years, animal models of radiation cataract have been utilized to test the short and long-term efficacy of various radiation countermeasures. While some compounds, most notably the Walter Reed (WR) class of radioprotectors, have reported limited effectiveness when given before exposure to low-LET radiation, the human toxicity of these molecules at effective doses limits their usefulness. Furthermore, while there has been considerable testing of eye responses to X- and gamma irradiation, there is limited information about using such models to limit the injurious effects of heavy ions and neutrons on eye tissue. A new class of radioprotector molecules, including the sulfhydryl compound PrC-210, are reported to be effective at much lower doses and with far less side effects. Their ability to modify ocular radiation damage has not yet been examined. The ability to non-invasively measure sensitive, radiation-induced ocular changes over long periods of time makes eye models an attractive option to test the radioprotective and radiation mitigating abilities of new novel compounds.

  16. Radiation effects on eye components

    International Nuclear Information System (INIS)

    Durchschlag, H.; Fochler, C.; Abraham, K.; Kulawik, B.

    1998-01-01

    The radiation damage (X-ray, UV light) of the most important components of the vertebrate eye (crystallins and other proteins, hyaluronic acid, vitreous, aqueous humour, ascorbic acid) has been investigated by various methods of physical chemistry. UV absorption and fluorescence spectroscopy as well as circular dichroism unveiled changes of the chromophores/fluorophores of the constituent biopolymers and low-molecular components, together with alterations of helix content and the occurrence of aggregation. Size-exclusion chromatography, analytical ultracentrifugation, densimetry, viscometry and light scattering experiments monitored changes of the global structure of proteins and polysaccharides involved. Electrophoreses allowed conclusions on fragmentation, unfolding and crosslinking. Analytical methods provided information regarding the integrity of groups of special concern (SH, SS) and revealed the existence of stable noxious species (H 2 O 2 ). By means of various measures and additives, manifold modifications of the impact of both ionizing and nonionizing radiation may be achieved. Caused by differences in the primary reactions, eye polymers are protected efficaciously by typical OH radical scavengers against X-irradiation, whereas compounds which exhibit absorption behavior in the UV range turn out to act as potent protectives ('chemical filters') against UV light. A few substances, such as ascorbate, are able to provide protection against both sorts of radiation and are even able to exhibit a slight chemical repair of already damaged particles. The results obtained are of importance for understanding pathological alterations of the eye (loss of transparency, cataractogenesis) and for developing new strategies for protection and repair of eye components. (author)

  17. Radiation effects on biodegradable polyesters

    International Nuclear Information System (INIS)

    Hiroshi Mitomo; Darmawan Darwis; Fumio Yoshii; Keizo Makuuchi

    1999-01-01

    Poly(3-hydroxybutyrate) [P(3HB)] and its copolymer poly(3-hydroxybutyrate-co-3hydroxyvalerate) [P(3HB-co-3HV)] are microbial biodegradable polyesters produced by many types of bacteria. Poly(butylene succinate) (PBS) and poly(E-caprolactone) (PCL) are also biodegradable synthetic polyesters which have been commercialized. These thermoplastics are expected for wide usage in environmental protection and blocompatible applications. Radiation grafting of hydrophilic monomers onto many polymers, e.g., polyethylene and polypropylene has been studied mainly for biomedical applications. In the present study, radiation-induced graft polymerization of vinyl monomers onto PHB and P(3HB-co-3HV) was carried out and improvement of their properties was studied. Changes in the properties and biodegradability were compared with the degree of grafting. Radiation-induced crosslinking of PBS and PCL which relatively show thermal and irradiation stability was also carried out to improve their thermal stability or processability. Irradiation to PBS and PCL mainly resulted in crosslinking and characterization of these crosslinked polyesters was investigated

  18. Perturbed effects at radiation physics

    International Nuclear Information System (INIS)

    Külahcı, Fatih; Şen, Zekâi

    2013-01-01

    Perturbation methodology is applied in order to assess the linear attenuation coefficient, mass attenuation coefficient and cross-section behavior with random components in the basic variables such as the radiation amounts frequently used in the radiation physics and chemistry. Additionally, layer attenuation coefficient (LAC) and perturbed LAC (PLAC) are proposed for different contact materials. Perturbation methodology provides opportunity to obtain results with random deviations from the average behavior of each variable that enters the whole mathematical expression. The basic photon intensity variation expression as the inverse exponential power law (as Beer–Lambert's law) is adopted for perturbation method exposition. Perturbed results are presented not only in terms of the mean but additionally the standard deviation and the correlation coefficients. Such perturbation expressions provide one to assess small random variability in basic variables. - Highlights: • Perturbation methodology is applied to Radiation Physics. • Layer attenuation coefficient (LAC) and perturbed LAC are proposed for contact materials. • Perturbed linear attenuation coefficient is proposed. • Perturbed mass attenuation coefficient (PMAC) is proposed. • Perturbed cross-section is proposed

  19. Status of research on biological effects and safety of electromagnetic radiation: telecommunications frequencies

    Energy Technology Data Exchange (ETDEWEB)

    Barnett, S B

    1994-06-01

    The possible adverse effects on human health of exposure to radiofrequency (RF) and microwave electromagnetic fields and radiation are of public concern. As the ambient electromagnetic environment continues to intensify (e.g. cellular and portable phones, wireless communications, LANs, PCNs) the effects of exposure from cumulative sources and prolonged exposure to low levels needs to be addressed. This review considers RF and microwave radiation above 100 kHz. It is acknowledged that there are several possible areas of biological interaction which have health implications and about which current knowledge is limited. Advice is based on the assessment of risks to health resulting from these exposures as derived from studies on the effects of RF radiation on animals and volunteers and from epidemiological studies of exposed populations. 360 refs., 9 tabs., 1 fig.

  20. Effective dose: a radiation protection quantity

    CERN Document Server

    Menzel, H G

    2012-01-01

    Modern radiation protection is based on the principles of justification, limitation, and optimisation. Assessment of radiation risks for individuals or groups of individuals is, however, not a primary objective of radiological protection. The implementation of the principles of limitation and optimisation requires an appropriate quantification of radiation exposure. The International Commission on Radiological Protection (ICRP) has introduced effective dose as the principal radiological protection quantity to be used for setting and controlling dose limits for stochastic effects in the regulatory context, and for the practical implementation of the optimisation principle. Effective dose is the tissue weighted sum of radiation weighted organ and tissue doses of a reference person from exposure to external irradiations and internal emitters. The specific normalised values of tissue weighting factors are defined by ICRP for individual tissues, and used as an approximate age- and sex-averaged representation of th...

  1. Non-targeted effects of ionising radiation

    International Nuclear Information System (INIS)

    Belyakov, O.V.

    2008-01-01

    The universality of the target theory of radiation-induced effects is challenged by observations on non-targeted effects such as bystander effects and genomic instability. Essential features of non-targeted effects are that they do not require direct nuclear exposure by radiation and they are particularly significant at low doses. This new evidence suggests a need for a new paradigm in radiation biology. The new paradigm would cover both the classical (targeted) and the non-targeted effects. New aspects include the role of cellular communication and tissue-level responses. A better understanding of non-targeted effects may have important consequences for health risk assessment and, consequently, on radiation protection. Non-targeted effects may contribute to the estimation of cancer risk from occupational, medical and environmental exposures. In particular, they may have implications for the applicability of the Linear-No-Threshold (LNT) model in extrapolating radiation risk data into the low-dose region. This also means that the adequacy of the concept of dose to estimate risk is challenged by these findings. Moreover, these effects may provide new mechanistic explanations for the development of non-cancer diseases. Further research is required to determine if these effects, typically measured in cell cultures, are applicable in tissue level, whole animals, and ultimately in humans. (orig.)

  2. Biological effects of high-energy radiation

    International Nuclear Information System (INIS)

    Curtis, S.B.

    1976-01-01

    The biological effects of high-energy radiation are reviewed, with emphasis on the effects of the hadronic component. Proton and helium ion effects are similar to those of the more conventional and sparsely ionizing x- and γ-radiation. Heavy-ions are known to be more biologically effective, but the long term hazard from accumulated damage has yet to be assessed. Some evidence of widely varying but dramatically increased effectiveness of very high-energy (approximately 70 GeV) hadron beams is reviewed. Finally, the importance of the neutron component in many situations around high-energy accelerators is pointed out

  3. Protective effect of corticosteroids on radiation pneumonitis in mice

    International Nuclear Information System (INIS)

    Gross, N.J.; Narine, K.R.; Wade, R.

    1988-01-01

    We explored the protective effect of corticosteroids on the mortality of mice that received thoracic irradiation. Methylprednisolone, 100 mg/kg/week, given from 11 weeks after gamma irradiation of the thorax resulted in an increase in the LD50 (11-26 weeks) from 14.3 +/- 0.3 (mean +/- SE) Gy to 17.6 +/- 0.4 Gy, P less than 0.001, a protection factor of 1.2. Withdrawal of steroids at various times during the period of radiation pneumonitis resulted in accelerated mortality in the next 2-4 weeks, so that the cumulative mortality caught up with that of control animals by 4 weeks after steroid withdrawal. However, after the end of the usual period of pneumonitis withdrawal of steroids did not result in accelerated mortality, suggesting that the time when steroids are protective corresponds to the duration of pneumonitis. A smaller dose of steroids, 25 mg/kg/week, was found to be as protective as the larger dose used in the above experiments. The possibility that corticosteroids reduce mortality, even when given many weeks after radiation, may have important practical and theoretical implications

  4. Biological effects and hazards of radiation exposure

    International Nuclear Information System (INIS)

    Boas, J.F.; Solomon, S.B.

    1990-01-01

    Radiation induced carcinogenesis and mutagenesis form the main risk to health from exposure to low levels of radiation. This risk effects can be at least qualitatively understood by considering the effects of radiation on cell DNA. Whilst exposure to high levels of radiation results in a number of identifiable effects, exposure to low levels of radiation may result in effects which only manifest themselves after many years. Risk estimates for low levels of radiation have been derived on the basis of a number of assumptions. In the case of uranium mine workers a major hazard arises from the inhalation of radon daughters. Whilst the correlation between radon daughter exposure and lung cancer incidence is well established, the numerical value of the risk factor is the subject of controversy. ICRP 50 gives a value of 10 cases per 10 6 person-years at risk per WLM (range 5-15 x 10 -6 PYR -1 WLM -1 ). The effect of smoking on lung cancer incidence rates amongst miners is also controversial. Nevertheless, smoking by miners should be discouraged

  5. Radiation abuse and its effects

    International Nuclear Information System (INIS)

    Halm, A.

    1976-01-01

    This paper delves into overuse practiced in diagnostic radiography. The conventional attitudes to low-dose irradiation are critically examined, as is the MPD related to individual radiosensitivity. Concern is expressed that a sizeable proportion of radiologists ignore important aspects of the Code of Practice and this attitude is readily emulated in the hospital setting. The author advocates education within the medical profession and the community on the risks involved in radiation abuse and the benefits derived from justified exposures to x rays. (author)

  6. Examination of cumulative effects of early adolescent depression on cannabis and alcohol use disorder in late adolescence in a community-based cohort.

    Science.gov (United States)

    Rhew, Isaac C; Fleming, Charles B; Vander Stoep, Ann; Nicodimos, Semret; Zheng, Cheng; McCauley, Elizabeth

    2017-11-01

    Although they often co-occur, the longitudinal relationship between depression and substance use disorders during adolescence remains unclear. This study estimated the effects of cumulative depression during early adolescence (ages 13-15 years) on the likelihood of cannabis use disorder (CUD) and alcohol use disorder (AUD) at age 18. Prospective cohort study of youth assessed at least annually between 6th and 9th grades (~ age 12-15) and again at age 18. Marginal structural models based on a counterfactual framework that accounted for both potential fixed and time-varying confounders were used to estimate cumulative effects of depressive symptoms over early adolescence. The sample originated from four public middle schools in Seattle, Washington, USA. The sample consisted of 521 youth (48.4% female; 44.5% were non-Hispanic White). Structured in-person interviews with youth and their parents were conducted to assess diagnostic symptom counts of depression during early adolescence; diagnoses of CUD and AUD at age 18 was based the Voice-Diagnostic Interview Schedule for Children. Cumulative depression was defined as the sum of depression symptom counts from grades 7-9. The past-year prevalence of cannabis and alcohol use disorder at the age 18 study wave was 20.9 and 19.8%, respectively. A 1 standard deviation increase in cumulative depression during early adolescence was associated with a 50% higher likelihood of CUD [prevalence ratio (PR) = 1.50; 95% confidence interval (CI) = 1.07, 2.10]. Although similar in direction, there was no statistically significant association between depression and AUD (PR = 1.41; 95% CI = 0.94, 2.11). Further, there were no differences in associations according to gender. Youth with more chronic or severe forms of depression during early adolescence may be at elevated risk for developing cannabis use disorder compared with otherwise similar youth who experience fewer depressive symptoms during early adolescence. © 2017 Society

  7. Survey of radiation doses and health effects in medical diagnostic X-ray workers in China

    International Nuclear Information System (INIS)

    Wang Jixian; Zhang Liangan; Liu Jinzhong; Zhang Jingyuan

    1984-01-01

    The results of a nationwide survey of radiation doses and health effects in 26983 medical diagnostic X-ray workers in 28 provinces of China were reported. The control group was composed of 25785 non-X-ray medical workers in the same hospitals where the investigated X-ray workers worked. Of the radiological workers surveyed 75.3% received cumulative radiation doses below 50 mGy, only 2.7% received doses greater than 500 mGy, the average cumulative dose being 45.0 mGy. The average length of service was 11 years. The main radiation effects relating to radiation doses were the increase of frequencies of both chromosomal aberrations and micronuclei in peripheral blood lymphocytes, which were 0.362% and 0.0358% in the irradiated group, and 0.122% and 0.0138% in the control group, respectively. The incidence and mortality rate of leukemias increased significantly in the irradiated group. The incidence and standardized incidence of leukemias were 9.61 . 10 -5 and 9.67 . 10 -5 in the irradiated group and 2.74 . 10 -5 and 2.77 . 10 -5 in the control group. The leukemia mortality rates in the two groups were 8.60 . 10 -5 and 1.24 . 10 -5 respectively, and the standardized mortality rates were 8.60 . 10 -5 and 1.27 . 10 -5 respectively. (Author)

  8. Biological Effects of Ionizing Radiation

    International Nuclear Information System (INIS)

    Durand, J.L.

    2000-01-01

    The aim of this work is to verify the existence of the adaptive response phenomenon induced by low doses of ionizing radiation in living cells.A wild-type yeast Saccharomyces cerevisiae (Baker's yeast) was chosen as the biological target.As a parameter to quantify the sensibility of the target to radiation, the Lethal Dose 50 (LD50 ) was observed. In our experimental condition a value of (60 ± 1) Gy was measured for LD50 with Dose Rate of (0.44 ± 0.03) Gy/min. The method employed to show up the adaptive response phenomenon consisted in exposing the sample to low ''conditioning'' doses, which would initiate these mechanisms. Later the samples with and without conditioning were exposed to higher ''challenging'' doses (such as LD50), and the surviving fractions were compared. In order to maximize the differences, the doses and the time between irradiations were varied. The best results were obtained with both a conditioning dose of (0.44 ± 0.03) Gy and a waiting time of 2 hs until the application of the challenging dose. Following this procedures the 80% of the conditioned samples has survived, after receiving the application of the LD50. The adaptive response phenomenon was also verified for a wide range of challenging doses

  9. Radiation effects on ion exchange materials

    International Nuclear Information System (INIS)

    Gangwer, T.E.; Goldstein, M.; Pillay, K.K.S.

    1977-11-01

    An extensive literature review and data compilation has been completed on the radiation-damage of ion exchange resins. The primary goal of the study has been to review the available literature on ion exchange materials used in, as well as those with potential for use in, the nuclear fuel and waste reprocessing areas. The physical and chemical properties of ion exchangers are reviewed. Experimental parameters useful in characterizing the effects of radiation on synthetic ion exchange resins are identified or defined. In compiling the diverse types of data, an effort was made to present the experimental data or experimentally based parameters in a format that would be useful for inter-comparing radiation effects on resins. When subject to radiation there are various general trends or qualitative effects displayed by the different types of resins. These radiation-trends and effects have been formulated into qualitative statements. The present day level of understanding of the behavior of resins under ionizing radiation is too limited to justify quantitative predictive modeling. The limitations and deficiencies of the literature are discussed and the experimentation needed to achieve quantitative modeling are outlined. 14 figs., 108 references

  10. Radiation effects on ion exchange materials

    Energy Technology Data Exchange (ETDEWEB)

    Gangwer, T.E.; Goldstein, M.; Pillay, K.K.S.

    1977-11-01

    An extensive literature review and data compilation has been completed on the radiation-damage of ion exchange resins. The primary goal of the study has been to review the available literature on ion exchange materials used in, as well as those with potential for use in, the nuclear fuel and waste reprocessing areas. The physical and chemical properties of ion exchangers are reviewed. Experimental parameters useful in characterizing the effects of radiation on synthetic ion exchange resins are identified or defined. In compiling the diverse types of data, an effort was made to present the experimental data or experimentally based parameters in a format that would be useful for inter-comparing radiation effects on resins. When subject to radiation there are various general trends or qualitative effects displayed by the different types of resins. These radiation-trends and effects have been formulated into qualitative statements. The present day level of understanding of the behavior of resins under ionizing radiation is too limited to justify quantitative predictive modeling. The limitations and deficiencies of the literature are discussed and the experimentation needed to achieve quantitative modeling are outlined. 14 figs., 108 references.

  11. Radiation effects on optical data transmission systems

    International Nuclear Information System (INIS)

    Leskovar, B.

    1989-01-01

    The state of the art of optical transmitters, low loss fiber waveguides and receivers in both steady state and pulsed radiation environments is reviewed and summarized. Emphasis is placed on the effects of irradiation on the performance of light emitting and laser diodes, optical fiber waveguides and photodiodes. The influence of radiation-induced attenuation of optical fibers due to total dose, dose rate, time after irradiation, temperature, radiation history, photobleaching, OH and impurity content, dopant type and concentration is described. The performance of candidate components of the transmission system intended for deployment in the Superconducting Super Collider Detector and primary beam tunnel nuclear environment is discussed

  12. Cumulative trauma and midlife well-being in American women who served in Vietnam: effects of combat exposure and postdeployment social support.

    Science.gov (United States)

    Park, Crystal L; Wachen, Jennifer Schuster; Kaiser, Anica Pless; Mager Stellman, Jeanne

    2015-01-01

    Research increasingly demonstrates that trauma exposure can have cumulative effects, yet much remains to be learned about effects of cumulative trauma, particularly regarding longer term adjustment. One such trauma, combat exposure, is insufficiently understood, especially for women, who are increasingly engaged in professional combat activities. The study comprised a cross-sectional survey assessing multiple aspects of current well-being in women approximately 25 years after their service in Vietnam during the Vietnam War. Participants were 1374 women (78% military and 22% nonmilitary; mean age = 59.7). This study investigated the relations between three separate categories of trauma exposure (childhood, adulthood, and combat) and well-being and examined whether perceived social support at return from Vietnam moderated the association between combat exposure and well-being. While both childhood and adulthood trauma exposure related to midlife well-being, combat exposure still uniquely predicted outcomes. Further, postdeployment perceived social support moderated the association of combat and well-being: recollected higher perceived social support at homecoming buffered participants from the links between combat exposure and well-being. These results may have important implications for interventions to reduce the impact of traumatic experiences, particularly in light of the increasing exposure of women to direct combat events.

  13. Radiation effects on the integrity of paper

    International Nuclear Information System (INIS)

    Otero D'Almeida, Maria Luiza; Medeiros Barbosa, Patricia de Souza; Boaratti, Marcelo Fernando Guerra; Borrely, Sueli Ivone

    2009-01-01

    Books and documents attacked by fungi and insects have already been treated by radiation for disinfestations purposes. However, there is still need to investigate the influence of radiation on the cellulose paper structure. The aim of this research was to study the effects of radiation on paper properties, especially those related to strength and appearance. Paper sheets for this study were prepared in the laboratory, using bleached eucalyptus pulp as raw material. No additives were used to concentrate the attention only on the effects of irradiation on the pure cellulose matrix. The samples were irradiated at IPEN's 60 Co Gammacell irradiator with six radiation doses, from 3 to 15 kGy at the dose rate 0.817 Gy/s. The properties of paper sheets were tested after irradiation and compared with unirradiated samples according to ISO methods. No significant changes were detected in paper samples irradiated up to 15 kGy.

  14. Effect of gamma radiation on Campylobacter jejuni

    International Nuclear Information System (INIS)

    Lambert, J.D.; Maxcy, R.B.

    1984-01-01

    Radiation resistance of Campylobacter jejuni in broth, ground beef, and ground turkey meat was determined using dose levels from 0-200 Krad at -30 +/- 10 0 C, at 0-5 0 C, and at 30 +/- 10 0 C. Irradiation at -30 0 C increased radiation resistance of cultures in ground meats; broth cultures were not greatly influenced by temperature. The effect of culture age on radiation resistance was also evaluated using cells in various physiological phases. Age did not have a pronounced effect on radiation resistance. The largest D 10 value for C. jejuni was 32 Krad, which was less than D 10 values commonly reported for salmonellae. 20 references, 4 figures

  15. Radiation effects on DNA methylation in mice

    International Nuclear Information System (INIS)

    Komura, J.; Kurishita, A.; Miyamura, Y.; Ono, T.; Tawa, R.; Sakurai, H.

    1992-01-01

    Effects of ionizing radiation on DNA methylation in liver, brain and spleen were examined by high performance liquid chromatography (HPLC). The total methylated cytosine level in the genome was reduced within 8 hours after 3.8 Gy of irradiation in liver of adult mice. But no appreciable effect was observed in brain and spleen. When mice were irradiated at newborn, liver DNA revealed no change in methylated cytosine level. Even though slight effects of radiation were detected in he methylation of the c-myc and c-fos genes, they were only temporary and no long-term effects were observed. These data suggest that the effect of radiation on DNA methylation in vivo is not prevailing a DNA damage, but rather influenced much through biological parameters. (author)

  16. Evidence for beneficial low level radiation effects and radiation hormesis

    International Nuclear Information System (INIS)

    Feinendegen, L.E.

    2005-01-01

    Low doses in the mGy range cause a dual effect on cellular DNA. One effect concerns a relatively low probability of DNA damage per energy deposition event and it increases proportional with dose, with possible bystander effects operating. This damage at background radiation exposure is orders of magnitudes lower than that from endogenous sources, such as ROS. The other effect at comparable doses brings an easily obeservable adaptive protection against DNA damage from any, mainly endogenous sources, depending on cell type, species, and metabolism. Protective responses express adaptive responses to metabolic perturbations and also mimic oxygen stress responses. Adaptive protection operates in terms of DNA damage prevention and repair, and of immune stimulation. It develops with a delay of hours, may last for days to months, and increasingly disappears at doses beyond about 100 to 200 mGy. Radiation-induced apoptosis and terminal cell differentiation occurs also at higher doses and adds to protection by reducing genomic instability and the number of mutated cells in tissues. At low doses, damage reduction by adaptive protection against damage from endogenous sources predictably outweighs radiogenic damage induction. The analysis of the consequences of the particular low-dose scenario shows that the linear-no-threshold (LNT) hypothesis for cancer risk is scientifically unfounded and appears to be invalid in favor of a threshold or hormesis. This is consistent with data both from animal studies and human epidemiological observations on low-dose induced cancer. The LNT hypothesis should be abandoned and be replaced by a hypothesis that is scientifically justified. The appropriate model should include terms for both linear and non-linear response probabilities. Maintaining the LNT-hypothesis as basis for radiation protection causes unressonable fear and expenses. (author)

  17. The radiation effects on the living cell

    International Nuclear Information System (INIS)

    Sage, E.; Dutrillaux, B.; Soussi, Th.; Boiteux, S.; Lopez, B.; Feunteun, J.

    1999-06-01

    This publication is a presentation of particular points discussed during the colloquium of the 15-18 june 1999, for which scientific researches are performed at the CEA/CNRS. They deal with the radiobiology, for the radiation effects on living matter; with the DNA, for the knowledge and repair mechanisms on cells submitted to ionizing radiations; with the exposition to UV in correlation with neoplasms; with the P53 gene which is a tumour suppressor. (A.L.B.)

  18. Genetic effects of radiation. Annex I

    International Nuclear Information System (INIS)

    1982-01-01

    This Annex is aimed at an updating of the 1977 UNSCEAR report, which presented a detailed review of the genetic effects of ionizing radiation, especially those parts that require significant revisions in the light of new data. There is an extensive bibliography with over 1000 references. Particular emphasis is given to those data that are relevant to the evaluation of genetic radiation hazards in man.

  19. Biological effect of radiation on human

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yun Sil; Cho, Chul Koo; Lee, Su Jae [and others

    2000-04-01

    1. Adaptive response when 0.01 Gy was preirradiated before high challenging dose is induced in normal cell types such normal lymphocytes, primary keratinocytes, and L929 fibroblast cells but not in neoplastic cells such as L5178Y lymphoma cells, EL-4 lymphoma cells and 308 papilloma cells. 2. Heat shock protein (HSP) 25 and inducible HSP70 is responsible for the induction of adaptive response and radioresistance - cell cycle regulation, antiapoptotic molecule and PKC activation were involved. 3. Apoptosis was induced at most 5. hrs after irradiation in primary keratinocytes, in v-rasHa transformed keratinocytes, the maximum interval was 16 hrs, and in 308 papilloma cells, the maximum was 48 hrs. 4. PKC response by radiation is correlated with induction of apoptosis. 5. Rapid induction PKCdelta in primary keratinocytes and no response of PKC epsilon may involved in radiation induced apoptosis. 6. The rate of resorption was increased when radiation was given at 2.5 days after gestation. Early death including foetal death were highly expressed when radiation was given at 7.5 days after gestation. There are no difference in incidence of late death including embryonic death. 7. 2 Gy is the most effective dose in radiation induced teratogenesis in mouse model. 8. Growth retardation and small head was present when radiation was given at 5.5, 7.5, 11.5 and 15.5 days after gestation and small head showed high incidence at 11.5 days after gestation. 9. External malformation, internal malformation and skeletal malformation was induced when radiation was given at 7.5 days after gestation. 10. OGG1-mutated cells induced radiosensitive by G2/M cell cycle arrest. 11. Radiation induced G2/M phase cell cycle and correlated with radiosensitivity. 12. PKCalpha induced differentiation. 13. Radiation exposed cells showed carcinogenic effect. 14. Organ specific radiosensitivity was shown and protein expression was involved.

  20. Biological effect of radiation on human

    International Nuclear Information System (INIS)

    Lee, Yun Sil; Cho, Chul Koo; Lee, Su Jae

    2000-04-01

    1. Adaptive response when 0.01 Gy was preirradiated before high challenging dose is induced in normal cell types such normal lymphocytes, primary keratinocytes, and L929 fibroblast cells but not in neoplastic cells such as L5178Y lymphoma cells, EL-4 lymphoma cells and 308 papilloma cells. 2. Heat shock protein (HSP) 25 and inducible HSP70 is responsible for the induction of adaptive response and radioresistance - cell cycle regulation, antiapoptotic molecule and PKC activation were involved. 3. Apoptosis was induced at most 5. hrs after irradiation in primary keratinocytes, in v-rasHa transformed keratinocytes, the maximum interval was 16 hrs, and in 308 papilloma cells, the maximum was 48 hrs. 4. PKC response by radiation is correlated with induction of apoptosis. 5. Rapid induction PKCdelta in primary keratinocytes and no response of PKC epsilon may involved in radiation induced apoptosis. 6. The rate of resorption was increased when radiation was given at 2.5 days after gestation. Early death including foetal death were highly expressed when radiation was given at 7.5 days after gestation. There are no difference in incidence of late death including embryonic death. 7. 2 Gy is the most effective dose in radiation induced teratogenesis in mouse model. 8. Growth retardation and small head was present when radiation was given at 5.5, 7.5, 11.5 and 15.5 days after gestation and small head showed high incidence at 11.5 days after gestation. 9. External malformation, internal malformation and skeletal malformation was induced when radiation was given at 7.5 days after gestation. 10. OGG1-mutated cells induced radiosensitive by G2/M cell cycle arrest. 11. Radiation induced G2/M phase cell cycle and correlated with radiosensitivity. 12. PKCalpha induced differentiation. 13. Radiation exposed cells showed carcinogenic effect. 14. Organ specific radiosensitivity was shown and protein expression was involved

  1. Radiation effects in corundum monocrystal

    International Nuclear Information System (INIS)

    Soulayman, S.; Attiah, J.; Molhem, A. G.

    2007-01-01

    It is found by this work that the irradiation of corundum monocrystals by energetic particles creates stable lattice defects, as a result of the atomic displacements to the sublattice. We have identified the colour centers (F and F + ) and more complex ones line [Al i + F]. This finding is in an agreement with the experimental results, available in the literature. We have also investigated the mechanism of occurrence of, so called 'radiation memory' in corundum monocrystals. This phenomenon reflects the fact that, after irradiation and annealing at high temperature and irradiation again by the quanta of x-rays, the absorption line 302 nm (4.1 eV) in the spectrum of optical absorption is restored in the range 200-650 nm. A comparison of our results with the results of other researchers in carried out. (author)

  2. Additive effects of ultraviolet radiation

    International Nuclear Information System (INIS)

    Cullen, A.P.

    1980-01-01

    A xenon-mercury high pressure lamp and a double monochromator were used to produce ultraviolet (uv) radiation at 295 nm. Pigmented rabbit eyes were irradiated and evaluated by slitlamp biomicroscopy. Corneal threshold (Hc) was 0.05 J.cm-2 and lens threshold (hL) was 0.75 J.cm-2. Other eyes were irradiated with 2 Hc and evaluated from 4 to 24 h at 4 h intervals. Corneal damage was only greater than that expected from a single Hc exposure if the separation between the two Hc exposures did not exceed 8 h. The most repeatable and reliable corneal response to these levels of uv was the development of corneal epithelial granules

  3. Size effect in radiation damage

    International Nuclear Information System (INIS)

    Brumovsky, M.

    1979-01-01

    Radiation embrittlement of nuclear reactor pressure vessel steels is mostly measured using small standard specimens in dynamic bend tests. Their dimensions are much smaller than those of the reactor. The increase in the critical temperature (transition temperature from the brittle-to-ductile fracture) is normally measured using standard Charpy-V type specimens or small CT-type specimens. This increase is then used as the main parameter for the pressure vessel safety evaluation. The philosophy of experiments is discussed used for the nonirradiated and irradiated pressure vessel steels. A comparison of the increase in the transition temperature measured in different types of specimens using various testing methods (static and dynamic bend tests with notch or crack) is also made. The results of this comparison and another study showed a relatively good agreement. (author)

  4. Radiation Effects on Spacecraft Structural Materials

    International Nuclear Information System (INIS)

    Wang, Jy-An J.; Ellis, Ronald J.; Hunter, Hamilton T.; Singleterry, Robert C. Jr.

    2002-01-01

    Research is being conducted to develop an integrated technology for the prediction of aging behavior for space structural materials during service. This research will utilize state-of-the-art radiation experimental apparatus and analysis, updated codes and databases, and integrated mechanical and radiation testing techniques to investigate the suitability of numerous current and potential spacecraft structural materials. Also included are the effects on structural materials in surface modules and planetary landing craft, with or without fission power supplies. Spacecraft structural materials would also be in hostile radiation environments on the surface of the moon and planets without appreciable atmospheres and moons around planets with large intense magnetic and radiation fields (such as the Jovian moons). The effects of extreme temperature cycles in such locations compounds the effects of radiation on structural materials. This paper describes the integrated methodology in detail and shows that it will provide a significant technological advance for designing advanced spacecraft. This methodology will also allow for the development of advanced spacecraft materials through the understanding of the underlying mechanisms of material degradation in the space radiation environment. Thus, this technology holds a promise for revolutionary advances in material damage prediction and protection of space structural components as, for example, in the development of guidelines for managing surveillance programs regarding the integrity of spacecraft components, and the safety of the aging spacecraft. (authors)

  5. Medical exposure and the effects of radiation

    International Nuclear Information System (INIS)

    Okuyama, Chio

    2011-01-01

    Radiation gives cracks to genes. The influence is divided into deterministic effect with a threshold value, and the stochastic effect (tumor and genetic effect) which increases according to the exposure amount. Although we are put to various non-artificial radiations, which we cannot be avoided, on the earth, the contamination by artificial radiation can be defended. Artificial radioactive exposure includes medical exposure and non-medical exposure for example by nuclear power plant. As to medical examinations using radiation, the inquiry about the radiation exposure is increasing after the occurrence of the first nuclear power plant disaster of Fukushima. While concern about non-medical radioactive exposure increases, the uneasiness to medical irradiation is also increasing. The dose limit by artificial radioactive exposure other than medical exposure is set up in order to prevent the influence on the health. While the dose limit of the public exposure is set to the lower value than the total dose of non-artificial exposure concerning of a safety margin for all people, the dose limit of medical exposure is not defined, since it is thought that medical irradiation has a benefit for those who receive irradiation. Making an effort to decrease the radiation dose in performing the best medical treatment is the responsibility with which we are burdened. (author)

  6. Radiation effects concerns at a spallation source

    International Nuclear Information System (INIS)

    Sommer, W.F.

    1990-01-01

    Materials used at spallation neutron sources are exposed to energetic particle and photon radiation. Mechanical and physical properties of these materials are altered; radiation damage on the atomic scale leads to radiation effects on the macroscopic scale. Most notable among mechanical-property radiation effects in metals and metal alloys are changes in tensile strength and ductility, changes in rupture strength, dimensional stability and volumetric swelling, and dimensional changes due to stress-induced creep. Physical properties such as electrical resistivity also are altered. The fission-reactor community has accumulated a good deal of data on material radiation effects. However, when the incident particle energy exceeds 50 MeV or so, a new form of radiation damage ensues; spallation reactions lead to more energetic atom recoils and the subsequent temporal and spatial distribution of point defects is much different from that due to a fission-reactor environment. In addition, spallation reactions cause atomic transmutations with these new atoms representing an impurity in the metal. The higher-energy case is of interest at spallation sources; limited detailed data exist for material performance in this environment. 35 refs., 13 figs., 1 tab

  7. CUMBIN - CUMULATIVE BINOMIAL PROGRAMS

    Science.gov (United States)

    Bowerman, P. N.

    1994-01-01

    The cumulative binomial program, CUMBIN, is one of a set of three programs which calculate cumulative binomial probability distributions for arbitrary inputs. The three programs, CUMBIN, NEWTONP (NPO-17556), and CROSSER (NPO-17557), can be used independently of one another. CUMBIN can be used by statisticians and users of statistical procedures, test planners, designers, and numerical analysts. The program has been used for reliability/availability calculations. CUMBIN calculates the probability that a system of n components has at least k operating if the probability that any one operating is p and the components are independent. Equivalently, this is the reliability of a k-out-of-n system having independent components with common reliability p. CUMBIN can evaluate the incomplete beta distribution for two positive integer arguments. CUMBIN can also evaluate the cumulative F distribution and the negative binomial distribution, and can determine the sample size in a test design. CUMBIN is designed to work well with all integer values 0 < k <= n. To run the program, the user simply runs the executable version and inputs the information requested by the program. The program is not designed to weed out incorrect inputs, so the user must take care to make sure the inputs are correct. Once all input has been entered, the program calculates and lists the result. The CUMBIN program is written in C. It was developed on an IBM AT with a numeric co-processor using Microsoft C 5.0. Because the source code is written using standard C structures and functions, it should compile correctly with most C compilers. The program format is interactive. It has been implemented under DOS 3.2 and has a memory requirement of 26K. CUMBIN was developed in 1988.

  8. Cumulation of light nuclei

    International Nuclear Information System (INIS)

    Baldin, A.M.; Bondarev, V.K.; Golovanov, L.B.

    1977-01-01

    Limit fragmentation of light nuclei (deuterium, helium) bombarded with 8,6 GeV/c protons was investigated. Fragments (pions, protons and deuterons) were detected within the emission angle 50-150 deg with regard to primary protons and within the pulse range 150-180 MeV/c. By the kinematics of collision of a primary proton with a target at rest the fragments observed correspond to a target mass upto 3 GeV. Thus, the data obtained correspond to teh cumulation upto the third order

  9. Radiation effects in LDD MOS devices

    International Nuclear Information System (INIS)

    Woodruff, R.L.; Adams, J.R.

    1987-01-01

    The purpose of this work is to investigate the response of lightly doped drain (LDD) n-channel transistors to ionizing radiation. Transistors were fabricated with conventional (non-LDD) and lightly doped drain (LDD) structures using both standard (non-hardened) and radiation hardened gate oxides. Characterization of the transistors began with a correlation of the total-dose effects due to 10 keV x-rays with Co-60 gamma rays. The authors find that for the gate oxides and transistor structures investigated in this work, 10 keV x-rays produce more fixed-charge guild-up in the gate oxide, and more interface charge than do Co-60 gamma rays. They determined that the radiation response of LDD transistors is similar to that of conventional (non-LDD) transistors. In addition, both standard and radiation-hardened transistors subjected to hot carrier stress before irradiation show a similar radiation response. After exposure to 1.0 x 10 6 rads(Si), non-hardened transistors show increased susceptibility to hot-carrier graduation, while the radiation-hardened transistors exhibit similar hot-carrier degradation to non-irradiated devices. The authors have demonstrated a fully-integrated radiation hardened process tht is solid to 1.0 x 10 6 rads(Si), and shows promise for achieving 1.0 x 10 7 rad(Si) total-dose capability

  10. Solar Radiation effect on the bituminous binder

    International Nuclear Information System (INIS)

    Tadeo Rico, A.; Torres Perez, A.

    2010-01-01

    Asphalt, used as binder in road construction, becomes more brittle and harder during working life on the surface of the road pavement, conducting toward their deterioration. This is caused by the oxidation of the molecular functional groups of the asphalt molecular structure. Moreover, it is observed that ultraviolet radiation increases the oxidation process. However, the effect of solar light on the asphalt degradation has been poorly researched. The aim of this work is to study asphalt ageing caused by effect of solar radiation, by using standard test. Four commercial asphalts from different companies were selected: two with penetration number 50/70, and the other two polymer modified asphalts. From each of the asphalts forty samples were taken off and placed in four different aging conditions of temperature and radiation for a period ranging from 40 to 500 days. Ring and Ball test, and Fraass breaking Point test, were used to analyse the changes of asphalt properties after exposition to solar radiation. The results of the four analyzed asphalts showed a distinct behaviour; not only in the test temperature increase but also in the rate. Another experiment was carried out. Samples from a hot mix asphalt batch were placed under solar radiation, and were compacted by the Marshall procedure after increasing periods of time. Density and resistance to plastic flow using Marshall Apparatus were measured. Results showed an increase in the stability of samples under radiation. Both experiments show that the solar radiation is enough to cause changes in the asphalt molecular structure due to oxidation. So that, the study of the effect of the solar radiation on the asphalt properties could be a good tool to asses the performances of asphalt pavement. (Author) 26 refs.

  11. Effects of radiation on aquatic organisms

    International Nuclear Information System (INIS)

    Kaur, Harbhajan; Lata, Poonam; Sharma, Ankush

    2012-01-01

    With the onset of nuclear age, nuclear fuel cycle products, nuclear medicine techniques, disposal of radio active wastes on land or in water, fall out of testing nuclear weapons has contributed large amount of radio nuclides to the water bodies. Radio nuclides can imbalance aquatic ecosystem resulting in danger to natural life. The biological effects of radiation on aquatic life are mortality, pathophysiological, reproductive, developmental and genetic changes. A broad review of the results obtained about the aquatic organisms related to different phyla indicates that the lower or less developed or more primitive organisms are more resistant than the higher or more advanced, developed and complex organisms to ionizing radiation. The algae, protozoa are more resistant than the insects, crustaceans, molluscs and fishes. The changes in sensitivity between different stages of development have also been noted. A review of the results of exposing salmonoid gametes, eggs, fingerlings and adults to X-rays supports the concepts that radio sensitivity decreases with age. This paper presents a selective review on effects of radiation and radio nuclides on the aquatic life. It include uses and sources of radiation, effective quantity of radiation, lethal and sub lethal effect, effects on survival, growth, reproduction, behaviour, metabolism, carcinogenicity and mutagenicity. (author)

  12. Cumulative Effects of Micro-Hydro Development on the Fisheries of the Swan River Drainage, Montana, First Annual Progress Report (Covering Field Season July-November 1982).

    Energy Technology Data Exchange (ETDEWEB)

    Leathe, Stephen A.; Graham, Patrick J.

    1984-03-01

    This fisheries study is to determine the potential cumulative biological and economic effects of 20 small or micro-hydro-electric facilities (less than 5 megawatts) proposed to be constructed on tributaries to the Swan River, a 1738 square kilometer (671 square mile) drainage located in northwestern Montana. The study addresses portions of measure 1204 (b) (2) of the Norwthwest Power Planning Council's Columbia River Basin Fish and Wildlife Program. Aerial pre-surveys conducted during 1982 identified 102 stream reaches that may support fish populations in the Swan drainage between Swan and Lindbergh lakes. These reaches were located in 49 tributary streams and constituted 416 kilometers (258 miles) of potential fish habitat. Construction of all proposed small hydro projects would divert water from 54 kilometers (34 miles) or about 13 percent of the tributary system. Only two of the 20 proposed hydro sites did not support trout populations and most were populated by migratory bull trout and westslope cutthroat trout. Potential cumulative habitat losses that could result from dewatering of all proposed project areas were predicted using a stream reach classification scheme involving stream gradient, drainage ara, and fish population data. Preliminary results of this worst case analysis indicate that 23, 19 and 6 percent of the high quality rearing habitat for cutthroat, bull, and brook trout respectively would be lost.

  13. Principles and techniques of radiation hardening. Volume 2. Transient radiation effects in electronics (TREE)

    International Nuclear Information System (INIS)

    Rudie, N.J.

    1976-01-01

    The three-volume book is intended to serve as a review of the effects of thermonuclear explosion induced radiation (x-rays, gamma rays, and beta particles) and the resulting electromagnetic pulse (EMP). Volume 2 deals with the following topics: radiation effects on quartz crystals, tantalum capacitors, bipolar semiconductor devices and integrated circuits, field effect transistors, and miscellaneous electronic devices; hardening electronic systems to photon and neutron radiation; nuclear radiation source and/or effects simulation techniques; and radiation dosimetry

  14. Environmental impacts of renewable energy. Geographic Information Systems (GIS) based analysis of cumulative effects; Umweltauswirkungen erneuerbarer Energien. GIS-gestuetzte Analyse kumulativer Wirkungen

    Energy Technology Data Exchange (ETDEWEB)

    Rhoden, Henning

    2015-04-15

    The energy transition and thus turning away from fossil fuels and nuclear energy sources is based on an increased expansion of renewable energies. This expansion mainly take place in nature and the landscape, which conflicts with the objectives of the Federal Nature Conservation Act concerning scenery or the consequences of monoculture cultivation of energy crops. What happens, however, if more than one type of renewables occur compressed in a landscape that is investigated in this work. Result from cumulative effects are extended conflict with the objectives of the Federal Nature Conservation Act or possibly have positive effects can be seen? A ''cumulative effect'' is defined as an additive-synergistic overall effect of all a protected interest of respective impact factors. These arise from one or more projects / plans and influence from a variety of ways. As part of the investigations carried out it is clear that extended conflicts may arise in relation to the objectives of the Federal Nature Conservation Act by cumulative effects of renewable energies. To prevent these conflicts, policies and regulations in the context of spatial planning is necessary to enable a focusing of spatial planning for a sustainable expansion of renewable energy. [German] Die Energiewende und damit die Abkehr von fossilen und atomaren Energiequellen beruht auf einem verstaerkten Ausbau der erneuerbaren Energien. Dieser Ausbau findet vorwiegend in Natur und Landschaft statt, wobei Konflikte mit den Zielen des BNatSchG z.B. hinsichtlich Landschaftsbild oder den Folgen von Monokultur beim Energiepflanzenanbau bereits gegeben sind. Was jedoch passiert, wenn mehrere Arten erneuerbarer Energien in einer Landschaft komprimiert auftreten, wird in dieser Arbeit untersucht. Ergeben sich aus kumulierten Wirkungen erweiterte Konflikte mit den Zielen des BNatSchG oder sind moeglicherweise positive Effekte zu erkennen? Eine ''kumulative Wirkung'' ist

  15. Health effects of low level radiation

    Energy Technology Data Exchange (ETDEWEB)

    Hattori, Sadao [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

    1998-12-31

    In 1982, Prof. Thomas Don Luckey of Missouri Univ. asserted `Radiation Hormesis` on the Journal of Health Physics and he published two books. CRIEPI initiated the research program on Radiation Hormesis following his assertion to confirm `is it true or not?` After nearly ten year research activities on data surveys and animal tests with many Universities, we are realizing scientific truth of bio-positive effects by low level radiation exposures. The interesting bio-positive effects we found could be categorized in following five groups. 1) Rejuvenation of cells such as increase of SOD and cell membrane permeability, 2) Moderation of psychological stress through response of key enzymes, 3) Suppression and therapy of adult-diseases such as diabetes and hypertension, 4) Suppression of cancer through enhancement of immune systems such as lymphocytes, 5) Suppression of cancer and ratio-adaptive response by activation of DNA repair and apoptosis. In the responses of many specialists to our initiation of radiation hormesis research program following T.D. Luckey`s claim about low level radiation, I have to pick up for the first, the great success of Prof. Sakamoto. Prof. Sakamoto had been already applying whole body low dose irradiation for ten years before our radiation hormesis research started on the therapy to suppress the cancer reappearing after treatment. He reported about his successful trial to real patients and showed an enhancement of immune system. (author)

  16. Health effects of low level radiation

    International Nuclear Information System (INIS)

    Hattori, Sadao

    1998-01-01

    In 1982, Prof. Thomas Don Luckey of Missouri Univ. asserted 'Radiation Hormesis' on the Journal of Health Physics and he published two books. CRIEPI initiated the research program on Radiation Hormesis following his assertion to confirm 'is it true or not?' After nearly ten year research activities on data surveys and animal tests with many Universities, we are realizing scientific truth of bio-positive effects by low level radiation exposures. The interesting bio-positive effects we found could be categorized in following five groups. 1) Rejuvenation of cells such as increase of SOD and cell membrane permeability, 2) Moderation of psychological stress through response of key enzymes, 3) Suppression and therapy of adult-diseases such as diabetes and hypertension, 4) Suppression of cancer through enhancement of immune systems such as lymphocytes, 5) Suppression of cancer and ratio-adaptive response by activation of DNA repair and apoptosis. In the responses of many specialists to our initiation of radiation hormesis research program following T.D. Luckey's claim about low level radiation, I have to pick up for the first, the great success of Prof. Sakamoto. Prof. Sakamoto had been already applying whole body low dose irradiation for ten years before our radiation hormesis research started on the therapy to suppress the cancer reappearing after treatment. He reported about his successful trial to real patients and showed an enhancement of immune system. (author)

  17. Radiation effects on bovine taste bud membranes

    International Nuclear Information System (INIS)

    Shatzman, A.R.; Mossman, K.L.

    1982-01-01

    In order to investigate the mechanisms of radiation-induced taste loss, the effects of radiation on preparations of enriched bovine taste bud membranes were studied. Taste buds containing circumvallate papilae, and surrounding control epithelial tissues devoid of taste buds, were obtained from steers and given radiation doses of 0-7000 cGy (rad). Tissue fractions were isolated into membrane-enriched and heterogeneous components using differential and sucrose gradient centrifugation of tissue homogenates. The yield of membranes, as measured by protein content in the buoyant membrane-enriched fractions, was reduced in quantity with increasing radiation dose. The relation between radiation dose and membrane quantity in membrane-enriched fractions could be fit by a simple exponential model with taste bud-derived membranes twice as radiosensitive as membranes from control epithelial tissue. Binding of sucrose, sodium, and acetate and fluoride stimulation of adenylate cyclase were nearly identical in both irradiated and nonirradiated intact membranes. Radiation had no effect on fractions of heterogeneous components. While it is not clear what changes are occurring in enriched taste cell membranes, damage to membranes may play an important role in the taste loss observed in patients following radiotherapy

  18. Effects of ionizing radiation on bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Suhadi, F [National Atomic Energy Agency, Jakarta (Indonesia). Pasar Djumat Research Centre

    1976-10-01

    The differences of radiosensitivities among bacteria in addition to the dependence upon the species or strains also depends on the environmental condition during irradiation (temperature, medium, the presence of protective or sensitizing agents, the gas phase or atmosphere, and water activity, or degree of hydration) and on the effects of the environmental condition before and after irradiation treatment (temperature of incubation, age of culture and growth medium). In general, spores are more resistant to radiation than vegetatic bacteria, with the exception that a few cocci are the most radiation resistant bacteria (Micrococcus and Streptococcus). The application of ionizing radiation in the fields of microbiology supports the radiation sterilization of medical and pharmaceutical products. In addition, microbiological aspects of food preservation, especially radurization, radicidation, and immunization studies by using irradiated microorganisms, are also important.

  19. Effect of radiation processing on meat tenderisation

    Science.gov (United States)

    Kanatt, Sweetie R.; Chawla, S. P.; Sharma, Arun

    2015-06-01

    The effect of radiation processing (0, 2.5, 5 and 10 kGy) on the tenderness of three types of popularly consumed meat in India namely chicken, lamb and buffalo was investigated. In irradiated meat samples dose dependant reduction in water holding capacity, cooking yield and shear force was observed. Reduction in shear force upon radiation processing was more pronounced in buffalo meat. Protein and collagen solubility as well as TCA soluble protein content increased on irradiation. Radiation processing of meat samples resulted in some change in colour of meat. Results suggested that irradiation leads to dose dependant tenderization of meat. Radiation processing of meat at a dose of 2.5 kGy improved its texture and had acceptable odour.

  20. The toxic effects of ionizing radiations

    International Nuclear Information System (INIS)

    Draghita Payet, A.C.

    2006-06-01

    The sources of radiations to which the human body is subjected are of natural or artificial origin and the irradiation of the human body can take place either by internal or external way. The ionizing radiations act at several levels of the human body, the main thing being the molecule of DNA. The ionizing radiations have no specificity, the effects on the human body can be: somatic, genetic or hereditary, teratogen. In the case of a human being irradiation, we proceed to the diagnosis and to the treatment of the irradiated person, however, to decrease the incidence of injuries we use the radiation protection. The treatment if necessary will be established according to the irradiation type. (N.C.)

  1. Effects of radiation on the skin

    International Nuclear Information System (INIS)

    Hopewell, J.W.

    1985-01-01

    The effects of X-irradiation on pig skin are described, comparing and contrasting the effects seen in human and rodent skin. It is concluded that, anatomically, pig skin is the best animal model for human skin. The applications of the 'pig skin model' to investigations of the problems of radiation therapy and radiological protection of human skin are discussed. (U.K.)

  2. CROSSER - CUMULATIVE BINOMIAL PROGRAMS

    Science.gov (United States)

    Bowerman, P. N.

    1994-01-01

    The cumulative binomial program, CROSSER, is one of a set of three programs which calculate cumulative binomial probability distributions for arbitrary inputs. The three programs, CROSSER, CUMBIN (NPO-17555), and NEWTONP (NPO-17556), can be used independently of one another. CROSSER can be used by statisticians and users of statistical procedures, test planners, designers, and numerical analysts. The program has been used for reliability/availability calculations. CROSSER calculates the point at which the reliability of a k-out-of-n system equals the common reliability of the n components. It is designed to work well with all integer values 0 < k <= n. To run the program, the user simply runs the executable version and inputs the information requested by the program. The program is not designed to weed out incorrect inputs, so the user must take care to make sure the inputs are correct. Once all input has been entered, the program calculates and lists the result. It also lists the number of iterations of Newton's method required to calculate the answer within the given error. The CROSSER program is written in C. It was developed on an IBM AT with a numeric co-processor using Microsoft C 5.0. Because the source code is written using standard C structures and functions, it should compile correctly with most C compilers. The program format is interactive. It has been implemented under DOS 3.2 and has a memory requirement of 26K. CROSSER was developed in 1988.

  3. Cardiovascular effects of radiation therapy

    International Nuclear Information System (INIS)

    Alvarez, Jose A.G.; Leiva, Gustavo

    2001-01-01

    Therapeutic mediastinal irradiation can induce heart disease with variable degree of cardiac engagement. Heart disease manifestations depend on the grade of involvement of the different cardiac structures. During the first two years following irradiation, pericarditis with or without pericardial effusion is the most common manifestation of toxicity related to radiation therapy. Later on, after a latency period of five to ten years, a constrictive pericarditis may develop. Other type of late cardiac toxicities due to irradiation are restrictive cardiomyopathy, multiple valvular disease, coronary artery disease and different atrioventricular conduction disturbances. The therapeutic approach to this kind of heart disease has to be focused on its progressive course and in the possibility of a global involvement of all the cardiac structures. Pericardiectomy is strongly recommended for recurrent pericardial effusion with cardiac tamponade. Cardiac surgery for myocardial revascularization or valvular disease can be performed with variable results; the presence of myocardial fibrosis can significantly affect perioperative management and long-term results. Cardiac transplantation is a promissory option for those patients with end-stage cardiac failure. Immunosuppressive regimens are not associated with recurrence of malignancy. (author) [es

  4. Radiation effects, nuclear energy and comparative risks

    International Nuclear Information System (INIS)

    Gopinath, D.V.

    2007-01-01

    Nuclear energy had a promising start as an unlimited, inexpensive and environmentally benign source of energy for electricity generation. However, over the decades its growth was severely retarded due to concerns about its possible detrimental effects on the well-being of mankind and the environment. Since such concerns are essentially due to the gigantic magnitude of radioactivity and ionizing radiations associated with nuclear energy, this article starts with a comprehensive account of effects of the ionizing radiation on living systems. Quantitative description of types of radiation exposure and their varied effects is given. The origin, type and magnitude of mutagenic effects of radiation are described. The concept of radiation risk factors, basis for their evaluation and their currently accepted values are presented. With this background, origin and magnitude of radioactivity and associated ionizing radiations in nuclear reactors are presented and the elaborate measures to contain them are described. It is recognized that notwithstanding all the measures taken in the nuclear industry, certain amount of radiation exposure, however small, is inevitable and the values, based on the experience world over, are presented. Estimated health risk due to such exposures is evaluated. For a comparative analysis, risks in other options of electricity generation such as hydel and fossil-fuelled plants are described. It is seen that on an overall basis, the nuclear option is no more risky than the other commonly employed options, and is in fact, significantly less. Lastly, since every option of electricity generation entails some risk, the case of 'no addition of electricity, and its impact on the society are considered. Based on the analysis of extensive data provided by UNDP on the human development parameters for different countries in the world, it is shown that at least for developing countries, any option of addition of electricity would be far more desirable than the

  5. Ionizing radiation effect on human reproduction

    International Nuclear Information System (INIS)

    Jirous, J.

    1987-01-01

    A review is presented of the existing knowledge on the adverse effects of ionizing radiation on human reproduction. Some interesting findings have been obtained by interapolating the results of studies in mouse embryos to humans, important knowledge has been obtained in studies involving the population of Hiroshima and Nagasaki. The review summarizes the knowledge in the following conclusions: (1) prior to the blastocyst stage, the mammalian embryo is insensitive to teratogenic and growth retarding radiation effects but is highly sensitive to the lethal radiation effect; (2) in the early organogenesis, the embryo is very sensitive to growth retarding, teratogenic and lethal radiation effects. It can, however, partly offset growth retardation in the post-natal period; (3) in the early fetal development stage, the fetus shows reduced sensitivity to teratogenic damage of many organs; sensitivity of the central nervous system and growth retardation remain which can only be compensated post-natally with difficulties; (4) in the late stage of pregnancy the fetus is not significantly deformed as a result of irradiation but permanent cellular depletion can result in various organs and tissues post-natally if radiation doses are high. (L.O.). 22 refs

  6. Cumulative human impacts on marine predators.

    Science.gov (United States)

    Maxwell, Sara M; Hazen, Elliott L; Bograd, Steven J; Halpern, Benjamin S; Breed, Greg A; Nickel, Barry; Teutschel, Nicole M; Crowder, Larry B; Benson, Scott; Dutton, Peter H; Bailey, Helen; Kappes, Michelle A; Kuhn, Carey E; Weise, Michael J; Mate, Bruce; Shaffer, Scott A; Hassrick, Jason L; Henry, Robert W; Irvine, Ladd; McDonald, Birgitte I; Robinson, Patrick W; Block, Barbara A; Costa, Daniel P

    2013-01-01

    Stressors associated with human activities interact in complex ways to affect marine ecosystems, yet we lack spatially explicit assessments of cumulative impacts on ecologically and economically key components such as marine predators. Here we develop a metric of cumulative utilization and impact (CUI) on marine predators by combining electronic tracking data of eight protected predator species (n=685 individuals) in the California Current Ecosystem with data on 24 anthropogenic stressors. We show significant variation in CUI with some of the highest impacts within US National Marine Sanctuaries. High variation in underlying species and cumulative impact distributions means that neither alone is sufficient for effective spatial management. Instead, comprehensive management approaches accounting for both cumulative human impacts and trade-offs among multiple stressors must be applied in planning the use of marine resources.

  7. Effects of UV radiation on freshwater metazooplankton

    International Nuclear Information System (INIS)

    Tartarotti, B.

    1999-06-01

    There is evidence that fluxes of solar ultraviolet-B radiation (UV-B, 290-320 nm) are increasing over wide parts of the earth's surface due to stratospheric ozone depletion. UV radiation (290-400 nm) can have damaging effects on biomolecules and cell components that are common to most living organisms. The aim of this thesis is to gain a more thorough understanding of the potential impacts of solar radiation on freshwater metazooplankton. To detect UV-vulnerability in zooplankton populations dominating the zooplankton community of two clear-water, high mountain lakes located one in the Austrian Alps and another in the Chilean Andes, the survival of two copepod species was studied. The organisms were exposed to a 10- to 100-fold increase in UV-B radiation compared to those levels found at their natural, maximum daytime distribution. Both species vertically migrate and are pigmented. UV-absorbing compounds with a maximum absorption at ∼334 nm were also detected. Cyclops abyssorum tatricus, a common cyclopoid copepod species of Alpine lakes, was highly resistant to UV-B radiation and no significant lethal effect was observed. The calanoid copepod Boeckella gracilipes, frequent in Andean lakes, had a mortality ∼5 times higher in the treatment receiving full sunlight than in the UV-B excluded treatment (3.2 %) only when exposed for 70 h. The resistance of B. gracilipes was higher than that reported in the literature for the same species suggesting the existence of intraspecific differences in UV sensitivity. Survival, fecundity and development of the zooplankton community of a clear-water, high elevation Andean lake (33 o S) were studied with mesocosms experiments after prolonged UV exposure (48 days). When exposed to full sunlight, the population of the cladoceran Chydorus sphaericus and the rotifer Lepadella ovalis were strongly inhibited by UV-B, whereas both species were resistant to UV-A radiation. Conversely, UV-B radiation had no effect on the survival of the

  8. The effects of balneotherapy on acute, process-related, and cumulative peripheral cardiac responses and pulmonary functions in patients with musculoskeletal disorders.

    Science.gov (United States)

    Şaş, Senem; Toprak Çelenay, Şeyda; Özer Kaya, Derya

    2016-12-20

    This study aimed to evaluate the effects of balneotherapy on acute, process-related, and cumulative peripheral cardiac responses and pulmonary functions in patients with musculoskeletal disorders. Ninety-eight patients with musculoskeletal disorders referred to physiotherapy with balneotherapy were recruited. The patients received balneotherapy for 20 min 5 times per week for 2 weeks. Blood pressure and pulse were measured at the 0th, 5th, 10th, 20th, and 30th minutes during the 1st and 10th sessions. All patients were subjected to pulmonary function testing before balneotherapy and after the 10th session. It was found that systolic blood pressure decreased between the 10th and 20th minutes of the 1st session and between the 10th and 20th minutes and the 20th and 30th minutes of the 10th session (P balneotherapy (P balneotherapy (P Balneotherapy may be effective for improving peripheral cardiopulmonary responses in patients with musculoskeletal disorders.

  9. Cytogenetic effects of low-dose radiation

    International Nuclear Information System (INIS)

    Metalli, P.

    1983-01-01

    The effects of ionizing radiation on chromosomes have been known for several decades and dose-effect relationships are also fairly well established in the mid- and high-dose and dose-rate range for chromosomes of mammalian cells. In the range of low doses and dose rates of different types of radiation few data are available for direct analysis of the dose-effect relationships, and extrapolation from high to low doses is still the unavoidable approach in many cases of interest for risk assessment. A review is presented of the data actually available and of the attempts that have been made to obtain possible generalizations. Attention is focused on some specific chromosomal anomalies experimentally induced by radiation (such as reciprocal translocations and aneuploidies in germinal cells) and on their relevance for the human situation. (author)

  10. The late biological effects of ionizing radiation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1978-06-15

    Full text: The principal objective of the symposium was to review the current status of understanding of the late biological effects of ionizing radiation from external and internal sources. A second objective was to critically evaluate information obtained from epidemiological studies of human population groups as well as from animal experimentation in order to provide a solid scientific basis upon which problems of current concern, such as radiation protection standards and risk-benefit analysis, could be deliberated. Eighty-one papers were presented in 10 sessions which covered epidemiological studies of late effects in human populations exposed to internal and/or external ionizing radiation; quantitative and qualitative data from animal experimentation of late effects; methodological problems and modern approaches; factors influencing susceptibility or expression of late radiation injury; comparative evaluation of late effects induced by radiation and other environmental pollutants, and problems of risk assessment. In addition, there were two evening sessions for free discussion of problems of interpreting animal data, and of the epidemiological studies of occupationally exposed populations. Reports on atomic bomb survivors showed that these epidemiological studies are providing dependable data, such as dose-related excess infant mortality. The reports also revealed the need for consensus in the method employed in the interpretation of data. That was also the case with studies on occupationally exposed populations at Hanford plant, where disparate results were presented on radiation-induced neoplasia among radiation workers. These data are, however, considered not so significant in relative terms when compared to risks involved in other industries. It was recommended that national registry systems for the dosimetry and medical records of radiation workers be established and co-ordinated internationally in order to facilitate reliable epidemiological

  11. Long-term effects of radiation

    International Nuclear Information System (INIS)

    Smith, J.; Smith, T.

    1981-01-01

    It is pointed out that sources of long-term damage from radiation are two-fold. People who have been exposed to doses of radiation from initial early fallout but have recovered from the acute effects may still suffer long-term damage from their exposure. Those who have not been exposed to early fallout may be exposed to delayed fallout, the hazards from which are almost exclusively from ingesting strontium, caesium and carbon isotopes present in food; the damage caused is relatively unimportant compared with that caused by the brief doses from initial radiation and early fallout. A brief discussion is presented of the distribution of delayed long-lived isotope fallout, and an outline is sketched of late biological effects, such as malignant disease, cataracts, retarded development, infertility and genetic effects. (U.K.)

  12. Effects of radiation on DNA

    International Nuclear Information System (INIS)

    Medina, V.F.O.

    1978-01-01

    Irradiation has been shown to depress DNA (deoxyribonucleic acid) synthesis resulting in deficient DNA synthesis. In one experiment, Hela S 3 cells completed the next division after a dose of 500 rads to 200 kw X-rays. Another experiment showed that the amount of DNA synthesized was dependent on the stage in the generation cycle at which the cells are irradiated (Giffites and Tolmach, 1975). DNA synthesis was measured by radioactive thymidine incorporation. The smallest deficiency (20-35%) after a dose of 500 rad X-ray was observed in Hela S 3 cells irradiated in early G 1 or early G 2 , while the greatest deficiency (55-70*) after 500 rad X-ray was found in cells irradiated at mitosis or at the Gsub(1)/S transition. Using velocity sedimentation in alkaline gradients of the DNA from hamster, Elkind, et al 1972, studied repair processes as a function of X-ray dose. DNA containing material released by alkaline lysis was found initially contained in a complex-containing lipid, the sedimentation of which was anomalous relative to denatured RNA from unirradated cells. Doses of X-rays small enough to be in the range that permits high survival (100-800 rads) speed the resolution of single-stranded DNA from this DNA complex, giving rise to a species having a number average molecular weight of 2 x 10 8 daltons. Larger doses greater than 1000 to 2000 rads resulted in a degradation of these DNA strands. Incubation after irradiation resulted in the rapid repair of damage, although the rate of repair of damage to the complex resulted in a reassociation of lipid and DNA. This evidence supports the possibility that a large DNA-membrane structure is a principal target of radiation

  13. Radiation absorbed dose estimates for [1-carbon-11]-glucose in adults: The effects of hyperinsulinemia

    International Nuclear Information System (INIS)

    Powers, W.J.

    1996-01-01

    As preparation for studies of blood-brain glucose transport in diabetes mellitus, radiation absorbed dose estimates from intravenous administration of [1- 11 C]-glucose for 24 internal organs, lens, blood and total body were calculated for three physiologic conditions: euinsulinemic euglycemia, hyperinsulinemic euglycemia and hyperinsulinemic hyperglycemia. Cumulated activities in blood, insulin-independent and insulin-dependent compartments were calculated from blood time-activity curves in normal human volunteers and macaques. Apportionment of cumulated activity to individual organs in insulin-dependent and insulin-independent compartments was based on previously published data. Absorbed doses were calculated with the computer program MIRDOSE 3 for the 70-kg adult phantom. S for blood was calculated separately. The heart wall, lungs and spleen were the organs receiving the highest dose. The effect of hyperinsulinemia was demonstrated by the increase in adsorbed dose to the muscle, heart and blood with a decrease to other internal organs. This effect was more pronounced during hyperinsulinemic hyperglycemia. Hyperinsulinemia produced a decrease in effective dose due to the decrease in cumulated activity in organs with specified weighting factors greater than 0.05. The effective dose per study for [1- 11 C]-glucose is comparable to that reported for 2-deoxy-[2- 18 F]-glucose. 43 refs., 1 fig., 4 tabs

  14. Ultra violet radiation : effects on animals

    International Nuclear Information System (INIS)

    Stockdale, P.H.G.

    1993-01-01

    The paper deals with the evolutionary and historical events that have increased the susceptibility of certain genotypes of humanity and domestic animals to ultra violet radiation. Further it discusses the general effects of ultraviolet B (UVB) on vertebrates and then the clinical syndromes seen in such animals as a result of prolonged exposure to this form of radiation. Finally it gives anecdotal comments on evidence for changes in the immediately above types of disease and describes the need for a better recording system for these conditions so that these hypothetical changes could be effectively monitored. (author). 12 refs

  15. Genetic and chromosomal effects of ionizing radiation

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    The genetic and chromosomal effects of ionizing radiations deal with those effects in the descendants of the individuals irradiated. The information base concerning genetic and chromosomal injury to humans from radiation is less adequate than is the information base for cancer and leukemia. As a result, it is not possible to make the kinds of quantitative estimates that have been made for carcinogenesis in previous chapters of this book. The chapter includes a detailed explanation of various types of genetic injuries such as chromosomal diseases, x-linked diseases, autosomal dominant diseases, recessive diseases, and irregularly inherited diseases. Quantitative estimates of mutation rates and incidences are given based on atomic bomb survivors data

  16. Additive effects in radiation grafting and curing

    International Nuclear Information System (INIS)

    Viengkhou, V.; Ng, L.

    1996-01-01

    Full text: Detailed studies on the accelerative effect of novel additives in radiation grafting and curing using acrylated monomer/oligomer systems have been performed in the presence of ionising radiation and UV as sources. Methyl methacrylate (MMA) is used as typical monomer for these grafting studies in the presence of the additives with model backbone polymers, cellulose and propropylene. Additives which have been found to accelerate these grafting processes are: mineral acid, occlusion compounds like urea, thermal initiators and photoinitiators as well as multifunctional monomers such as multifunctional acrylates. The results from irradiation with gamma rays have also been compared with irradiation from a 90W UV lamp. The role of the above additives in accelerating the analogous process of radiation curing has been investigated. Acrylated urethanes, epoxies and polyesters are used as oligomers together with acrylated monomers in this work with uv lamps of 300 watts/inch as radiation source. In the UV curing process bonding between film and substrate is usually due to physical forces. In the present work the presence of additives are shown to influence the occurrence of concurrent grafting during cure thus affecting the nature of the bonding of the cured film. The conditions under which concurrent grafting with UV can occur will be examined. A mechanism for accelerative effect of these additives in both grafting and curing processes has been proposed involving radiation effects and partitioning phenomena

  17. Ex-situ and in-situ observations of the effects of gamma radiation on lithium ion battery performance

    Science.gov (United States)

    Tan, Chuting; Bashian, Nicholas H.; Hemmelgarn, Chase W.; Thio, Wesley J.; Lyons, Daniel J.; Zheng, Yuan F.; Cao, Lei R.; Co, Anne C.

    2017-07-01

    Radiation effects induced by gamma rays on battery performance were investigated by measuring the capacity and resistance of a series of battery coin cells in-situ directly under gamma radiation and ex-situ. An experimental setup was developed to charge and discharge batteries directly under gamma radiation, equipped with precise temperature control, at The Ohio State University Nuclear Reactor Lab. Latent effects induced by gamma radiation on battery components directly influence their performance. Charge and discharge capacity and overall resistance throughout a time span of several weeks post irradiation were monitored and compared to control groups. It was found that exposure to gamma radiation does not significantly alter the available capacity and the overall cell resistance immediately, however, battery performance significantly decreases with time post irradiation. Also, batteries exposed to a higher cumulative dose showed close-to-zero capacity at two-week post irradiation.

  18. Radiation effects on custom MOS devices

    International Nuclear Information System (INIS)

    Harris, R.

    1999-05-01

    This Thesis consists of four chapters: The first is primarily for background information on the effects of radiation on MOS devices and the theory of wafer bonding; the second gives a full discussion of all practical work carried out for manufacture of Field Effect test Capacitors, the third discusses manufacture of vacuum insulator Field Effect Transistors (FET's) and the fourth discusses the testing of these devices. Using a thermally bonded field effect capacitor structure, a vacuum dielectric was studied for use in high radiation environments with a view to manufacturing a CMOS compatible, micro machined transistor. Results are given in the form of high frequency C-V curves before and after a 120 kGy(Si), 12 MRad(Si), dose from a Co 60 source showing a 1 Volt shift. The work is then extended to the design and manufacture of a micro machined, under-etch technique, Field Effect Transistor for use in high radiation areas. Results are shown for Threshold, Subthreshold and Transfer characteristics before and after irradiation up to a total dose of 100kGy or 10MRad. The conclusion from this work is that it should be possible to commercially manufacture practical vacuum dielectric field effect transistors which are radiation hard to at least 120 kGy(Si). (author)

  19. Effect on intelligence of prenatal exposure to ionizing radiation

    International Nuclear Information System (INIS)

    Schull, W.J.; Otake, Masanori.

    1987-01-01

    Analysis of intelligence test scores at 10 - 11 years of age of individuals exposed prenatally to the atomic bombing of Hiroshima and Nagasaki has revealed the following: 1) For those individuals exposed in the first eight weeks after fertilization or after the 25th week, there is no evidence of a radiation-related effect on intelligence; 2) The mean test scores but not the variances are significantly heterogeneous among exposure categories for individuals exposed at 8 - 15 weeks after fertilization, and to a lesser extent those exposed at 16 - 25 weeks; 3) The regression of intelligence score on estimated fetal tissue dose is linear or linear-quadratic for the 8 - 15 week group and possibly linear for the 16 - 25 week group; 4) The cumulative distributions of test scores suggest a progressive shift downwards in the scores with increasing exposure; and 5) Within the group most sensitive to the occurrence of clinically recognizable, severe mental retardation, individuals exposed 8 to 15 weeks after fertilization, the diminution in intelligence score under the linear-quadratic model is 21 - 27 points at 1 gray (Gy = 100 cGy = 100 rad). The effect is somewhat greater when the controls receiving less than 0.01 Gy are excluded, 33 - 41 points at 1 Gy; but the two estimates are not statistically significantly different. (author)

  20. Ceramics radiation effects issues for ITER

    International Nuclear Information System (INIS)

    Zinkle, S.J.

    1993-01-01

    The key radiation effects issues associated with the successful operation of ceramic materials in components of the planned International Thermonuclear Experimental Reactor (ITER) are discussed. Radiation-induced volume changes and degradation of the mechanical properties should not be a serious issue for the fluences planned for ITER. On the other hand, radiation-induced electrical degradation effects may severely limit the allowable exposure of ceramic insulators. Degradation of the loss tangent and thermal conductivity may also restrict the location of some components such as ICRH feedthrough insulators to positions far away from the first wall. In-situ measurements suggest that the degradation of physical properties in ceramics during irradiation is greater than that measured in postirradiation tests. Additional in-situ data during neutron irradiation are needed before engineering designs for ITER can be finalized