WorldWideScience

Sample records for culturally sensitive programs

  1. Culturally Sensitive Refugee Mental Health Training Programs.

    Science.gov (United States)

    Minnesota Univ., Minneapolis. Refugees Assistance Program - Mental Health Technical Assistance Center.

    This report, based on a survey conducted during the summer and fall of 1986, identifies culturally sensitive training programs for professionals, paraprofessionals, and others who provide mental health services to refugees. An introductory section discusses the language, cultural, racial, experiential, and socioeconomic factors of refugee mental…

  2. Educational Policy vs. Culturally Sensitive Programs in Turkish Educational System

    Science.gov (United States)

    Arslan, Hasan

    2009-01-01

    The purpose of this study is to examine the perceptions of elementary school teachers about the sensitiveness of principals, teachers, and curriculum on multicultural education. Education provides the transmission and the advancement of its culture while it is developing and enhancing the common values, the integrity and the progress of…

  3. Culturally Sensitive Best Practices for Sex Education Programs

    Science.gov (United States)

    D'Santiago, Verenice; Hund, Alycia M.

    2012-01-01

    Learning about sexuality is a lifelong process that begins in childhood and continues through the lifespan. Through family and peer interactions and media sources, youth learn about sexuality and relationships, and develop their own values. The learning process and trajectory, however, may differ among youth from diverse cultures. In fact,…

  4. Implementation and evaluation of a low health literacy and culturally sensitive diabetes education program.

    Science.gov (United States)

    Swavely, Deborah; Vorderstrasse, Allison; Maldonado, Edgardo; Eid, Sherrine; Etchason, Jeff

    2014-01-01

    Low health literacy is more prevalent in persons with limited education, members of ethnic minorities, and those who speak English as a second language, and is associated with multiple adverse diabetes-related health outcomes. This study examined the effectiveness of a low health literacy and culturally sensitive diabetes education program for economically and socially disadvantaged adult patients with type 2 diabetes. A pre-post prospective study design was used to examine outcomes over 12 months. Outcome measures included diabetes knowledge, self-efficacy, and self-care, measured using reliable and valid survey tools, and A1C. Over this period of time 277 patients were enrolled in the program, with 106 participants completing survey data. At the completion of the program patients had significant improvements in diabetes knowledge (p diabetes education program designed to be culturally sensitive and meet the needs of individuals with low health literacy improves short-term outcomes. © 2013 National Association for Healthcare Quality.

  5. Developing cultural sensitivity

    DEFF Research Database (Denmark)

    Ruddock, Heidi; Turner, deSalle

    2007-01-01

    . Background. Many countries are becoming culturally diverse, but healthcare systems and nursing education often remain mono-cultural and focused on the norms and needs of the majority culture. To meet the needs of all members of multicultural societies, nurses need to develop cultural sensitivity......Title. Developing cultural sensitivity: nursing students’ experiences of a study abroad programme Aim. This paper is a report of a study to explore whether having an international learning experience as part of a nursing education programme promoted cultural sensitivity in nursing students...... and incorporate this into caregiving. Method. A Gadamerian hermeneutic phenomenological approach was adopted. Data were collected in 2004 by using in-depth conversational interviews and analysed using the Turner method. Findings. Developing cultural sensitivity involves a complex interplay between becoming...

  6. Culturally sensitive assessment.

    Science.gov (United States)

    Edwards, C P; Kumru, A

    1999-04-01

    Issues of cultural interaction and culturally sensitive assessment and treatment of young children have become prominent in recent years for mental health professionals, for reasons having to do with changing demographics, public values, and professional vision. "Culture" refers to the sociocultural adaptation of design for living shared by people as members of a community. Mental health professionals who work with culturally diverse populations need to become culturally self-aware and find abstract and experiential ways to build a useful body of professional knowledge concerning childrearing and discipline practices, health and illness beliefs, communication styles, and expectations about family or professional relations or other group interactions. They also need to learn how to work effectively in intercultural teams, use families as partners and resources, train and work with interpreters, and select and use formal and nonformal assessment procedures in appropriate, culturally sensitive ways.

  7. Culture-sensitive psychotraumatology

    Directory of Open Access Journals (Sweden)

    Ulrich Schnyder

    2016-07-01

    Full Text Available Background: Although there is some evidence of the posttraumatic stress disorder (PTSD construct's cross cultural validity, trauma-related disorders may vary across cultures, and the same may be true for treatments that address such conditions. Experienced therapists tailor psychotherapy to each patient's particular situation, to the nature of the patient's psychopathology, to the stage of therapy, and so on. In addition, culture-sensitive psychotherapists try to understand how culture enhances the meaning of their patient's life history, the cultural components of their illness and help-seeking behaviors, as well as their expectations with regard to treatment. We cannot take for granted that all treatment-seeking trauma survivors speak our language or share our cultural values. Therefore, we need to increase our cultural competencies. Methods: The authors of this article are clinicians and/or researchers from across the globe, working with trauma survivors in various settings. Each author focused on one or more specific cultural aspects of working with trauma survivors and highlighted the following aspects. Results: As a result of culture-specific individual and collective meanings linked to trauma and trauma-related disorders survivors may be exposed to (self-stigma in the aftermath of trauma. Patients who are reluctant to talk about their traumatic experiences may instead be willing to write or use other ways of accessing the painful memories such as drawing. In other cultures, community and family cohesion are crucial elements of recovery. While awareness of culture-specific aspects is important, we also need to beware of premature cultural stereotyping. When disseminating empirically supported psychotherapies for PTSD across cultures, a number of additional challenges need to be taken into account: many low and middle income countries have very limited resources available and suffer from a poor health infrastructure. Conclusions: In summary

  8. Culture-sensitive psychotraumatology

    Science.gov (United States)

    Schnyder, Ulrich; Bryant, Richard A.; Ehlers, Anke; Foa, Edna B.; Hasan, Aram; Mwiti, Gladys; Kristensen, Christian H.; Neuner, Frank; Oe, Misari; Yule, William

    2016-01-01

    Background Although there is some evidence of the posttraumatic stress disorder (PTSD) construct's cross cultural validity, trauma-related disorders may vary across cultures, and the same may be true for treatments that address such conditions. Experienced therapists tailor psychotherapy to each patient's particular situation, to the nature of the patient's psychopathology, to the stage of therapy, and so on. In addition, culture-sensitive psychotherapists try to understand how culture enhances the meaning of their patient's life history, the cultural components of their illness and help-seeking behaviors, as well as their expectations with regard to treatment. We cannot take for granted that all treatment-seeking trauma survivors speak our language or share our cultural values. Therefore, we need to increase our cultural competencies. Methods The authors of this article are clinicians and/or researchers from across the globe, working with trauma survivors in various settings. Each author focused on one or more specific cultural aspects of working with trauma survivors and highlighted the following aspects. Results As a result of culture-specific individual and collective meanings linked to trauma and trauma-related disorders survivors may be exposed to (self-)stigma in the aftermath of trauma. Patients who are reluctant to talk about their traumatic experiences may instead be willing to write or use other ways of accessing the painful memories such as drawing. In other cultures, community and family cohesion are crucial elements of recovery. While awareness of culture-specific aspects is important, we also need to beware of premature cultural stereotyping. When disseminating empirically supported psychotherapies for PTSD across cultures, a number of additional challenges need to be taken into account: many low and middle income countries have very limited resources available and suffer from a poor health infrastructure. Conclusions In summary, culture-sensitive

  9. Fulfilling Their Dreams: Marginalized Urban Youths' Perspectives on a Culturally Sensitive Social and Emotional Learning Program

    Science.gov (United States)

    Slaten, Christopher D.; Rivera, Roberto C.; Shemwell, Daniel; Elison, Zachary M.

    2016-01-01

    A growing body of research suggests educators need to focus on cultivating social and emotional competencies that youth will need to thrive in the new knowledge economy (Durlak, Weissberg, Dymnicki, Taylor, & Schellinger, 2011). For marginalized urban youth, in particular, few have derived programs and interventions to assist with these…

  10. A culturally sensitive Transition Assistance Program for stroke caregivers: Examining caregiver mental health and stroke rehabilitation

    Directory of Open Access Journals (Sweden)

    Paul B. Perrin, MS

    2010-09-01

    Full Text Available This study developed and implemented the Transition Assistance Program (TAP for stroke caregivers. The program is composed of (1 skill development, (2 education, and (3 supportive problem solving. Sixty-one dyads (n = 122 participated: thirty-nine from Puerto Rico and twenty-two from Texas. Participants were randomly assigned to the TAP treatment or a control group. As caregiver satisfaction with the TAP increased, strain and depression decreased, and caregivers reported a very high rate of program satisfaction (9.5 out of 10. The TAP effectively reduced caregiver strain at the 3-month follow-up. When controlling for baseline differences, we found that the treatment group had lower depression (p = 0.07 than the control group at follow-up and that the TAP may have had a preventative effect on depression for caregivers who had not been depressed at discharge, although this visual trend did not reach statistical significance. Among veterans with low functioning at baseline, veterans whose caregivers had received the TAP improved in functioning more than did veterans whose caregivers had been in the control group, although this visual trend was not significant. Functioning in veterans with stroke was also significantly linked to caregiver satisfaction with the TAP. The findings from the current study warrant further evaluation of the TAP intervention.

  11. Can Discipline Education be Culturally Sensitive?

    Science.gov (United States)

    Smith, Ashley E; Hudnut-Beumler, Julia; Scholer, Seth J

    2017-01-01

    Objectives Inappropriate discipline such as harsh physical punishment is a social determinant of health. The objective was to determine if a brief parent training intervention that teaches discipline strategies is culturally sensitive. Methods English or Spanish-speaking parents of 1-5 year old children viewed a multimedia program that teaches appropriate discipline strategies. The intervention, Play Nicely, was viewed in the exam room before the physician's visit. Parents viewed 4 of 20 discipline strategies of their choosing; the average viewing time was 7 min. Results Of 204 parents eligible to participate, 197 (96 %) completed the study; 41 % were Black, 31 % were White, and 21 % were Hispanic. At least 80 % of parents from each racial/ethnic group reported that the program built their confidence to care for their child, addressed their family needs, explained things in a way they could understand, respected their family values, and was sensitive to their personal beliefs. Overall, 80 % of parents reported that the program answered individual questions. One parent (0.5 %) reported that the program did not respect her family values. Conclusions for Practice Discipline education can be integrated into the pediatric primary care clinic in a way that is family-centered and culturally sensitive for the majority of parents. The results have implications for the development and implementation of population-based parenting programs and the primary prevention of child abuse and violence.

  12. Culturally-Sensitive Learning Practices

    Science.gov (United States)

    Farmer, Lesley S. J.

    2010-01-01

    In today's global world, to provide meaningful education, teacher-librarians and their students need to become culturally competent: open to learning about other cultures and sharing one's own culture, able to change personal perspectives, and able to communicate effectively across cultures. Hofstede's model of cultural dimensions provides a…

  13. Continuing professional development in sensitive cultures.

    Science.gov (United States)

    Huntington, Mark K

    2008-01-01

    Many cultures of the world face threats to their existence due to the homogenizing effects of the global commercial pop culture. These same influences present challenges to vulnerable cultures that seek the benefits of modern medicine, while attempting to preserve their unique identities. This paper briefly reviews some of these challenges and presents one novel approach to providing continuing medical education that minimizes the potential for adverse influences on the sensitive culture.

  14. Culture-sensitive adaptation and validation of the community-oriented program for the control of rheumatic diseases methodology for rheumatic disease in Latin American indigenous populations.

    Science.gov (United States)

    Peláez-Ballestas, Ingris; Granados, Ysabel; Silvestre, Adriana; Alvarez-Nemegyei, José; Valls, Evart; Quintana, Rosana; Figuera, Yemina; Santiago, Flor Julian; Goñi, Mario; González, Rosa; Santana, Natalia; Nieto, Romina; Brito, Irais; García, Imelda; Barrios, Maria Cecilia; Marcano, Manuel; Loyola-Sánchez, Adalberto; Stekman, Ivan; Jorfen, Marisa; Goycochea-Robles, Maria Victoria; Midauar, Fadua; Chacón, Rosa; Martin, Maria Celeste; Pons-Estel, Bernardo A

    2014-09-01

    The purpose of the study is to validate a culturally sensitive adaptation of the community-oriented program for the control of rheumatic diseases (COPCORD) methodology in several Latin American indigenous populations. The COPCORD Spanish questionnaire was translated and back-translated into seven indigenous languages: Warao, Kariña and Chaima (Venezuela), Mixteco, Maya-Yucateco and Raramuri (Mexico) and Qom (Argentina). The questionnaire was administered to almost 100 subjects in each community with the assistance of bilingual translators. Individuals with pain, stiffness or swelling in any part of the body in the previous 7 days and/or at any point in life were evaluated by physicians to confirm a diagnosis according to criteria for rheumatic diseases. Overall, individuals did not understand the use of a 0-10 visual analog scale for pain intensity and severity grading and preferred a Likert scale comprising four items for pain intensity (no pain, minimal pain, strong pain, and intense pain). They were unable to discriminate between pain intensity and pain severity, so only pain intensity was included. For validation, 702 subjects (286 male, 416 female, mean age 42.7 ± 18.3 years) were interviewed in their own language. In the last 7 days, 198 (28.2 %) subjects reported having musculoskeletal pain, and 90 (45.4 %) of these had intense pain. Compared with the physician-confirmed diagnosis, the COPCORD questionnaire had 73.8 % sensitivity, 72.9 % specificity, a positive likelihood ratio of 2.7 and area under the receiver operating characteristic curve of 0.73. The COPCORD questionnaire is a valid screening tool for rheumatic diseases in indigenous Latin American populations.

  15. A Sixth Sense--Cultural Sensitivity.

    Science.gov (United States)

    Jackson, Francesina R.

    1996-01-01

    This article presents suggestions for culturally sensitive modifications to help students from all backgrounds learn better. The modifications include building trust, building a repertoire of instructional strategies, using effective questioning techniques, providing effective feedback, analyzing instructional materials, and establishing positive…

  16. Culture, Personality, Health, and Family Dynamics: Cultural Competence in the Selection of Culturally Sensitive Treatments

    Science.gov (United States)

    Sperry, Len

    2010-01-01

    Cultural sensitivity and cultural competence in the selection of culturally sensitive treatments is a requisite for effective counseling practice in working with diverse clients and their families, particularly when clients present with health issues or medical problems. Described here is a strategy for selecting culturally sensitive treatments…

  17. The effect of culture on pain sensitivity.

    Science.gov (United States)

    Al-Harthy, M; Ohrbach, R; Michelotti, A; List, T

    2016-02-01

    Cross-cultural differences in pain sensitivity have been identified in pain-free subjects as well as in chronic pain patients. The aim was to assess the impact of culture on psychophysical measures using mechanical and electrical stimuli in patients with temporomandibular disorder (TMD) pain and pain-free matched controls in three cultures. This case-control study compared 122 female cases of chronic TMD pain (39 Saudis, 41 Swedes and 42 Italians) with equal numbers of age- and gender-matched TMD-free controls. Pressure pain threshold (PPT) and tolerance (PPTo) were measured over one hand and two masticatory muscles. Electrical perception threshold and electrical pain threshold (EPT) and tolerance (EPTo) were recorded between the thumb and index fingers. Italian females reported significantly lower PPT in the masseter muscle than other cultures (P cultures (P = 0.017). Italians reported significantly lower PPTo in all muscles than Swedes (P ≤ 0.006) and in the masseter muscle than Saudis (P cultures (P = 0.01). Temporomandibular disorder cases, compared to TMD-free controls, reported lower PPT and PPTo in all the three muscles (P cultural differences between groups in the PPT, PPTo and EPTo. Overall, Italian females reported the highest sensitivity to both mechanical and electrical stimulation, while Swedes reported the lowest sensitivity. Mechanical pain thresholds differed more across cultures than did electrical pain thresholds. Cultural factors may influence response to type of pain test.

  18. Revising and Updating the Inventory of Cross-Cultural Sensitivity

    Science.gov (United States)

    Mahon, Jennifer A.; Cushner, Kenneth

    2014-01-01

    The following article outlines research conducted to examine cross-cultural sensitivity in a sample of 949 incoming university students in the USA. The study was conducted during the process of updating an existing measure of cross-cultural sensitivity known as the Inventory of Cross-Cultural Sensitivity (ICCS), and to examine the various levels…

  19. Is Ethical Sensitivity in Teaching Culturally Bound? Comparing Finnish and Iranian Teachers' Ethical Sensitivity

    Science.gov (United States)

    Gholami, Khalil; Kuusisto, Elina; Tirri, Kirsi

    2015-01-01

    In this study, we investigated the culture-invariant and culture-dependent nature of teachers' ethical sensitivity in two countries. Our case study involves teachers from Finland (n = 864) representing Western culture, and from Iran (n = 556) representing Eastern culture. Culturally bound elements of ethical sensitivity were studied with the…

  20. A cross-cultural mentoring program

    Energy Technology Data Exchange (ETDEWEB)

    Huang-Nissen, S.; Myers, R.Y.

    1995-04-01

    This report summarized the results of the pilot Cross-Cultural Mentoring Program at Lawrence Livermore National Laboratory, from the inception of the program idea through its implementation and assessment. It discusses the benefits of mentoring, the origins of the program, program design and implementation, program assessment, and conclusions and recommendations.

  1. A cross-cultural mentoring program

    Energy Technology Data Exchange (ETDEWEB)

    Huang-Nissen, S.; Myers, R.Y.

    1995-04-01

    This report summarized the results of the pilot Cross-Cultural Mentoring Program at Lawrence Livermore National Laboratory, from the inception of the program idea through its implementation and assessment. It discusses the benefits of mentoring, the origins of the program, program design and implementation, program assessment, and conclusions and recommendations.

  2. Diversifying the Midwifery Workforce: Inclusivity, Culturally Sensitive Bridging, and Innovation.

    Science.gov (United States)

    Tyson, Holliday; Wilson-Mitchell, Karline

    2016-11-01

    Midwifery educators and regulators in Canada have begun to address diversity, equity, and inclusion in admission processes and program curricula. Populations served by midwives value internationally educated midwives from their countries of origin. The International Midwifery Pre-Registration Program at Ryerson University in Toronto, Ontario, provides assessment, midwifery workplace orientation, and accelerated education for internationally educated midwives on behalf of the regulatory College of Midwives of Ontario. Between 2003 and 2015, midwives from 41 countries participated in the bridging program, and 214 (80%) successfully completed the program and qualified for licensure. Of these 214 graduates, 100% passed the Canadian Midwifery Registration Examination and 193 (90%) were employed full time as midwives within 4 months of graduation. The program curriculum enables the integration of these midwives into health care workplaces utilizing innovative approaches to assessment and competency enhancement. Critical to the bridging process are simulation-based practices to develop effective psychomotor learning, virtual and real primary care community placements, and coaching in empathetic, client-centered communication. Cultural sensitivity is embedded into the multiple assessment and learning modalities, and addresses relevant barriers faced by immigrant midwives in the workplace. Findings from the 13 years of the program may be applicable to increase diversity in other North American midwifery settings. This article describes the process, content, outcomes, and findings of the program. Midwifery educators and regulators may consider the utility of these approaches for their settings. © 2016 by the American College of Nurse-Midwives.

  3. What Is a Moose? Becoming Culturally Sensitive Leaders.

    Science.gov (United States)

    Goldenberg, Lori; Wilhite, Barbara

    1996-01-01

    At a summer camp that introduces Japanese high school students to American culture, the authors learned the following basic principles underlying culturally responsive camp activities: sensitivity to cultural nuances in communication, deliberate and sequential processes, appreciation of one's own cultural biases, understanding perceived risks, and…

  4. Knowledge, programming, and programming cultures: LISP, C, and Ada

    Science.gov (United States)

    Rochowiak, Daniel

    1990-01-01

    The results of research 'Ada as an implementation language for knowledge based systems' are presented. The purpose of the research was to compare Ada to other programming languages. The report focuses on the programming languages Ada, C, and Lisp, the programming cultures that surround them, and the programming paradigms they support.

  5. Culturally Sensitive Health Care and Counseling Psychology: An Overview

    Science.gov (United States)

    Herman, Keith C.; Tucker, Carolyn M.; Ferdinand, Lisa A.; Mirsu-Paun, Anca; Hasan, Nadia T.; Beato, Cristina

    2007-01-01

    This article introduces the Major Contribution, which focuses on counseling psychologists' roles in addressing health disparities through culturally sensitive health care research and interventions. First, the authors provide a rationale for conducting research focused on culturally sensitive health care and then offer definitions of…

  6. Making Career Theories More Culturally Sensitive: Implications for Counseling

    Science.gov (United States)

    Young, Richard A.; Marshall, Sheila K.; Valach, Ladislav

    2007-01-01

    The primary question addressed in this article is whether and how career theories can be more culturally sensitive without losing value as conceptual explanations or their usefulness for counselors. Contextual action theory is identified as a means to develop culturally sensitive explanations. Six steps are proposed and illustrated, including…

  7. Culture and religion in nursing: providing culturally sensitive care.

    Science.gov (United States)

    Mendes, Aysha

    Last month, Aysha Mendes discussed the impact on care of personal beliefs held by both nurses and patients. This month, she delves into the aspects of culture and religion, which form important pieces of this puzzle, as well as the importance of culturally appropriate care provision in nursing practice.

  8. Practitioners' Perspectives on Cultural Sensitivity in Latina/o Teen Pregnancy Prevention

    Science.gov (United States)

    Wilkinson-Lee, Ada M.; Russell, Stephen T.; Lee, Faye C. H.

    2006-01-01

    This study examined practitioners' understandings of cultural sensitivity in the context of pregnancy prevention programs for Latina teens. Fifty-eight practitioners from teen pregnancy prevention programs in California were interviewed in a guided conversation format. Three themes emerged in our analysis. First, practitioners' definitions of…

  9. Predicting Changes in Cultural Sensitivity among Students of Spanish during Short-Term Study Abroad

    Science.gov (United States)

    Martinsen, Rob

    2011-01-01

    Short-term study abroad programs of less than a semester are becoming increasingly popular among undergraduate students in the United States. However, little research has examined the changes in students' cultural sensitivity through their participation in such programs or what factors may predict growth and improvement in such areas. This study…

  10. Culturally sensitive curriculum development in international cooperation

    NARCIS (Netherlands)

    Gervedink Nijhuis, C.J.

    2012-01-01

    To assure high quality education in developing countries, curriculum development endeavours are often initiated as part of international cooperation projects. Since culture affects the educational context of the countries involved and the way in which curriculum developers from different countries

  11. Islamic Cultural Sensitivity in the Marine Corps

    Science.gov (United States)

    2008-02-19

    Marine Corps. Others argue that the newly revised Counterinsurgency Field Manual and implementation of the Marine Corps Martial Arts Program...also argued that the Marine Corps Martial Arts Program highlights the fact that issues such as winning the hearts and minds and respect for

  12. A Culture-Sensitive Agent in Kirman's Ant Model

    Science.gov (United States)

    Chen, Shu-Heng; Liou, Wen-Ching; Chen, Ting-Yu

    The global financial crisis brought a serious collapse involving a "systemic" meltdown. Internet technology and globalization have increased the chances for interaction between countries and people. The global economy has become more complex than ever before. Mark Buchanan [12] indicated that agent-based computer models will prevent another financial crisis and has been particularly influential in contributing insights. There are two reasons why culture-sensitive agent on the financial market has become so important. Therefore, the aim of this article is to establish a culture-sensitive agent and forecast the process of change regarding herding behavior in the financial market. We based our study on the Kirman's Ant Model[4,5] and Hofstede's Natational Culture[11] to establish our culture-sensitive agent based model. Kirman's Ant Model is quite famous and describes financial market herding behavior from the expectations of the future of financial investors. Hofstede's cultural consequence used the staff of IBM in 72 different countries to understand the cultural difference. As a result, this paper focuses on one of the five dimensions of culture from Hofstede: individualism versus collectivism and creates a culture-sensitive agent and predicts the process of change regarding herding behavior in the financial market. To conclude, this study will be of importance in explaining the herding behavior with cultural factors, as well as in providing researchers with a clearer understanding of how herding beliefs of people about different cultures relate to their finance market strategies.

  13. Culturally sensitive curriculum development in international cooperation

    NARCIS (Netherlands)

    Gervedink Nijhuis, C.J.

    2012-01-01

    To assure high quality education in developing countries, curriculum development endeavours are often initiated as part of international cooperation projects. Since culture affects the educational context of the countries involved and the way in which curriculum developers from different countries a

  14. Empathy and Cross-Cultural Sensitivity.

    Science.gov (United States)

    Steward, Robbie J.; Jo, Hanik; Roberts, Amber

    Multicultural empathy has been recognized as an important factor in successfully treating ethnic minority clients. A study detailing the relationship between White counselor trainees' general ability to empathize and their ability to interact comfortably outside their culture of origin is described in this paper. Thirty-three counselor trainees…

  15. Examination of Cultural Shock, Inter-Cultural Sensitivity and Willingness to Adapt

    Science.gov (United States)

    D'Souza, Clare; Singaraju, Stephen; Halimi, Tariq; Sillivan Mort, Gillian

    2016-01-01

    Purpose: The purpose of this paper is to identify themes on international experiences that impact culture and how these findings will intervene in understanding cross-cultural training programs. Thereby an attempt is made to: evaluate cross-cultural insensitivity influences on cross-cultural shock and willingness to adapt, identify cultural…

  16. Integrative Report on a culture-sensitive quality & curriculum framework

    NARCIS (Netherlands)

    Sylva, Kathy; Ereky-Stevens, Katharina; Pastori, Giulia; Slot, P.L.; Lerkkanen, Marja-Kristiina

    2016-01-01

    This report draws together research findings that support a comprehensive culture-sensitive European curriculum and quality assessment framework that can inform practice, teacher education and policy. The aim of this integrative report is to inform the development of a comprehensive, culture-sensiti

  17. Cuento Therapy: A Culturally Sensitive Modality for Puerto Rican Children.

    Science.gov (United States)

    Costantino, Giuseppe; And Others

    1986-01-01

    Investigated the effectiveness of a modeling therapy designed to be sensitive to Hispanic culture using cuentos (folktales) from Puerto Rican culture to present models of adaptive behavior and folktales tailored to bridge Puerto Ricans' bicultural conflict. Cuento therapy significantly reduced children's trait anxiety relative to traditional…

  18. Cultural Competence in Afterschool Programs

    Science.gov (United States)

    Simpkins, Sandra D.; Riggs, Nathaniel R.

    2014-01-01

    Increasing ethnic diversity among American youth, in combination with funding priorities often targeting underserved populations, has increased the number of diverse youth attending afterschool programs (ASPs). At present, there is little guidance on how to best design ASPs and prepare staff to support the development of these diverse youth. The…

  19. Moving toward cultural competency: DREAMWork online summer program.

    Science.gov (United States)

    Harris, Martina S; Purnell, Kathy; Fletcher, Audwin; Lindgren, Katherine

    2013-01-01

    This article describes the origination and implementation of an online, interactive summer component of the Diversity Recruitment and Education to Advance Minorities in the Nursing Workforce Program (DREAMWork) at University of Tennessee at Chattanooga (UTC). The summer course was designed as a strategy to help prepare baccalaureate nursing students to provide both culturally sensitive and competent care through online learning. Sixteen baccalaureate nursing students participated in the four week online summer program. Course objectives were framed using Campinha-Bacote's (2002) model of cultural competence (Figure 1). Analysis revealed at the end of the four week summer program, students were more comfortable discussing their own prejudices and biases and were left with a deeper appreciation of what it meant to provide culturally sensitive care. The results of this summer program suggest the need to expand the online course to allow DREAMWork pre-nursing students to address the issue of becoming culturally competent prior to admission into upper division nursing clinical courses. This project was supported by funds from the Division of Nursing (DN), Bureau of Health Professions (BHPr), Health Resources and Services Administration (HRSA), Department of Health and Human Services (DHHS) under grant # D19HP08214.

  20. Improving the sensitivity of blood culture for Streptococcus pneumoniae.

    Science.gov (United States)

    Saha, Samir; Darmstadt, Gary; Naheed, Aliya; Arifeen, Shams; Islam, Maksuda; Fatima, Kaniz; Breiman, Robert; Sack, David; Hamer, Davidson

    2011-06-01

    Isolation of Streptococcus pneumoniae is jeopardized by low sensitivity of blood culture, autolysis and contamination with fast-growing organism(s). We performed an immunochromatographic (ICT) test for S. pneumoniae on chocolatized blood culture bottles and also sub-cultured contaminated bottles on a selective medium, thus identifying an additional eight and three cases, respectively, and improving the detection of pneumococcus by 23% (48% vs. 59%). Prescreening of culture bottles in a blinded fashion could rationalize the use of ICT with ~99% accuracy. These two approaches can aid microbiology laboratories in resource-poor countries to substantially improve rates of detection of S. pneumoniae.

  1. The Effects of the Japan Bridge Project on Third Graders' Cultural Sensitivity

    Science.gov (United States)

    Meyer, Lindsay; Sherman, Lilian; MaKinster, James

    2006-01-01

    This study examines the effects of the Japan BRIDGE Project, a global education program, on its third grade participants. Characterization of lessons and analysis of student interviews were used to investigate the nature of the curriculum and whether or not student participants were more culturally sensitive due to participation. Results indicate…

  2. Trainer Perceptions of Culture, Race and Ethnicity on Facilitation of Training Programs: A Global Perspective

    Science.gov (United States)

    Pesch, Mari Jo

    2007-01-01

    This qualitative study examined how trainers perceive and manage training programs with racially and ethnically diverse participants. Five themes emerged: global perspective, learning styles and culturally diverse participants, facilitation style, preparation for training with culturally diverse groups and, culturally sensitive training materials.…

  3. Intergroup anxiety, cultural sensitivity and socio-cultural diverse leaders’ effectiveness

    Directory of Open Access Journals (Sweden)

    María Laura Lupano Peruginni

    2015-01-01

    Full Text Available This intended to analyze differences in the level of perception –of general population participants- in regards to leaders with diverse socio-cultural characteristics (gender, sexual orientation, religious affiliation, nationality and also verify by means of structural equations, the influence of intergroup anxiety and the cultural sensitivity in terms of the level of effectiveness perception. Participants: 481 adults from Argentina (52.8% female, 47.2% male; age average = 35.45 years old. Instruments: Intergroup Anxiety scale, Cultural Sensitivity scale, and an ad hoc protocol designed to assess level of effectiveness perception in socio-culturally diverse leaders. Results: Differences in the level of perception of effectiveness according to sociocultural characteristics could not be confirmed. However, a direct effect of cultural sensitivity and an indirect effect of intergroup anxiety on the levels of effectiveness perception were confirmed. This work contributes to previous studies on prejudice and leadership.

  4. Native American Youth and Culturally Sensitive Interventions: A Systematic Review

    Science.gov (United States)

    Jackson, Kelly F.; Hodge, David R.

    2010-01-01

    Objective: A systematic evaluation of the effectiveness of culturally sensitive interventions (CSIs) with Native American youth was conducted. Method: Electronic bibliographic databases, Web sites, and manual searches were used to identify 11 outcome studies that examined CSI effectiveness with Native American youth. Results: This review found…

  5. Culturally Sensitive Dementia Caregiving Models and Clinical Practice

    Science.gov (United States)

    Daire, Andrew P.; Mitcham-Smith, Michelle

    2006-01-01

    Family caregiving for individuals with dementia is an increasingly complex issue that affects the caregivers' and care recipients' physical, mental, and emotional health. This article presents 3 key culturally sensitive caregiver models along with clinical interventions relevant for mental health counseling professionals.

  6. Building Cultural Sensitivity and Interprofessional Collaboration Through a Study Abroad Experience.

    Science.gov (United States)

    Gilliland, Irene; Attridge, Russell T; Attridge, Rebecca L; Maize, David F; McNeill, Jeanette

    2016-01-01

    Study abroad (SA) experiences for health professions students may be used to heighten cultural sensitivity to future patients and incorporate interprofessional education (IPE). Two groups of nursing and pharmacy students participated in an SA elective over a 2-year period, traveling to China and India. Both groups improved significantly in knowledge, awareness, and skills following the travel experiences. Student reflections indicate that the SA experience was transformative, changing their views of travel, other cultures, personal environment, collaboration with other health professionals, and themselves. Use of SA programs is a novel method to encourage IPE, with a focus on enhancing the acquisition of cultural competency skills. Copyright 2016, SLACK Incorporated.

  7. Development of culturally sensitive dialog tools in diabetes education

    Directory of Open Access Journals (Sweden)

    Nana Folmann Hempler

    2015-01-01

    Full Text Available Person-centeredness is a goal in diabetes education, and cultural influences are important to consider in this regard. This report describes the use of a design-based research approach to develop culturally sensitive dialog tools to support person-centered dietary education targeting Pakistani immigrants in Denmark with type 2 diabetes. The approach appears to be a promising method to develop dialog tools for patient education that are culturally sensitive, thereby increasing their acceptability among ethnic minority groups. The process also emphasizes the importance of adequate training and competencies in the application of dialog tools and of alignment between researchers and health care professionals with regards to the educational philosophy underlying their use.

  8. Cultural competence education in university rehabilitation programs.

    Science.gov (United States)

    Matteliano, Mary A; Stone, John H

    2014-01-01

    The Center of International Rehabilitation Research, Information, and Exchange (CIRRIE) has prepared curriculum guides for rehabilitation professionals in occupational therapy, physical therapy, speech language pathology, and rehabilitation counseling. The objective is to provide a resource to faculty who wish to include or strengthen cultural competency education in their program and courses. CIRRIE assessed students'cultural needs, and solicited assistance from experts in the field to assist with the development of the guides. After the guides were published CIRRIE conducted surveys to assess their usefulness. Survey responses were highest among occupational therapy faculty. Among faculty who responded, most intended to use the cultural competence activities, case studies, and resources that the guides offer throughout their curriculum.

  9. Bifurcations and sensitivity in parametric nonlinear programming

    Science.gov (United States)

    Lundberg, Bruce N.; Poore, Aubrey B.

    1990-01-01

    The parametric nonlinear programming problem is that of determining the behavior of solution(s) as a parameter or vector of parameters alpha belonging to R(sup r) varies over a region of interest for the problem: Minimize over x the set f(x, alpha):h(x, alpha) = 0, g(x, alpha) is greater than or equal to 0, where f:R(sup (n+r)) approaches R, h:R(sup (n+r)) approaches R(sup q) and g:R(sup (n+r)) approaches R(sup p) are assumed to be at least twice continuously differentiable. Some of these parameters may be fixed but not known precisely and others may be varied to enhance the performance of the system. In both cases a fundamentally important problem in the investigation of global sensitivity of the system is to determine the stability boundaries of the regions in parameter space which define regions of qualitatively similar solutions. The objective is to explain how numerical continuation and bifurcation techniques can be used to investigate the parametric nonlinear programming problem in a global sense. Thus, first the problem is converted to a closed system of parameterized nonlinear equations whose solution set contains all local minimizers of the original problem. This system, which will be represented as F(z,alpha) = O, will include all Karush-Kuhn-Tucker and Fritz John points, both feasible and infeasible solutions, and relative minima, maxima, and saddle points of the problem. The local existence and uniqueness of a solution path (z(alpha), alpha) of this system as well as the solution type persist as long as a singularity in the Jacobian D(sub z)F(z,alpha) is not encountered. Thus the nonsingularity of this Jacobian is characterized in terms of conditions on the problem itself. Then, a class of efficient predictor-corrector continuation procedures for tracing solution paths of the system F(z,alpha) = O which are tailored specifically to the parametric programming problem are described. Finally, these procedures and the obtained information are illustrated

  10. Strategies for Context Sensitive Program Transformation

    NARCIS (Netherlands)

    Olmos Joffré, K.R.

    2009-01-01

    In this thesis we study the implementation of program transformations at a high abstraction level. We believe this leads to better productivity of the transformation developer. A program transformation system is a computer program which main goal is the transformation of programs. There are several

  11. Automatic Damage Detection for Sensitive Cultural Heritage Sites

    Science.gov (United States)

    Cerra, D.; Tian, J.; Lysandrou, V.; Plank, S.

    2016-06-01

    The intentional damages to local Cultural Heritage sites carried out in recent months by the Islamic State (IS) have received wide coverage from the media worldwide. Earth Observation data is an important tool to assess these damages in such non-accessible areas: If a fast response is desired, automated image processing techniques would be needed to speed up the analysis. This paper shows the first results of applying fast and robust change detection techniques to sensitive areas. A map highlighting potentially damaged buildings is derived, which could help experts at timely assessing the damages to the Cultural Heritage sites in the observed images.

  12. Sensitivity and rapidity of blood culture bottles in the detection of cornea organ culture media contamination by bacteria and fungi

    OpenAIRE

    Thuret, G; Carricajo, A.; Chiquet, C.; Vautrin, A C; Celle, N; Boureille, M; Acquart, S; Aubert, G.; Maugery, J; Gain, P.

    2002-01-01

    Aims: To test the bactericidal activity of standard organ culture medium, and to compare the sensitivity and rapidity of blood culture bottles with conventional microbiological methods for detection of bacteria and fungi inoculated in a standard cornea organ culture medium.

  13. Greek Immigrants in Australia: Implications for Culturally Sensitive Practice.

    Science.gov (United States)

    Georgiades, Savvas Daniel

    2015-10-01

    This exploratory research examined adjustment challenges, resiliencies, attitudes, emotional health, economic stability, criminal involvement, victimization and service experiences, and some cultural propensities of Greek Immigrants (GIs) in Australia using a convenient multi-generational sample (n = 123; response rate = .5). Data were collected via surveys, telephone, and personal-interviews in four major Australian cities. Among other things, the study revealed that Greek identity and cultural customs are often significant to first generation GIs. Adjustment challenges upon entry include primarily language, housing, and transportation difficulties, nostalgia for relatives and the motherland, unfamiliarity with socio-cultural systems, unemployment, money challenges, and lack of friendships. Christian faith, the extended family, family values and traditions, cultural pride for ancient Greek achievements, and a hard 'work ethic' are notable resiliencies that support GIs in their struggles and solidify their pursuit for happiness and success. Financial concerns, aging, and nostalgia for relatives and the motherland were the primary causes of socio-emotional instability. Attitudinal differences in the respondents based on age, gender, and socio-economic status, cross-cultural comparisons, and recommendations for culturally-sensitive practice with GIs are analyzed and methodological limitations illuminated. Future research needs in the field are also highlighted.

  14. Can transfer programs be made more nutrition sensitive?:

    OpenAIRE

    Alderman, Harold

    2014-01-01

    Malnutrition can best be addressed by a combination of nutrition specific interventions and nutrition sensitive programs, including social protection. This study reviews mechanisms of transfer program in order to better design nutrition sensitive social protection. Social protection programs typically increase income as well as influence the timing and, to a degree, control of this income. Additionally, social protection programs may achieve further impact on nutrition by fostering linkages w...

  15. Optimum sensitivity derivatives of objective functions in nonlinear programming

    Science.gov (United States)

    Barthelemy, J.-F. M.; Sobieszczanski-Sobieski, J.

    1983-01-01

    The feasibility of eliminating second derivatives from the input of optimum sensitivity analyses of optimization problems is demonstrated. This elimination restricts the sensitivity analysis to the first-order sensitivity derivatives of the objective function. It is also shown that when a complete first-order sensitivity analysis is performed, second-order sensitivity derivatives of the objective function are available at little additional cost. An expression is derived whose application to linear programming is presented.

  16. International Cultural Immersion: Assessing the Influence of a Group Intervention on Intercultural Sensitivity for Counselor Trainees

    Science.gov (United States)

    Barden, Sejal M.; Shannonhouse, Laura; Mobley, Keith

    2015-01-01

    Scholars (e.g., Bemak & Chung, 2004) underscore the need for group workers to be culturally sensitive. One group training strategy, cultural immersion, is often employed to develop cultural sensitivity. However, no studies have utilized quasi-experimental methodologies to assess differences in cultural sensitivity between trainees that immerse…

  17. TEACH (Train to Enable/Achieve Culturally Sensitive Healthcare)

    Science.gov (United States)

    Maulitz, Russell; Santarelli, Thomas; Barnieu, Joanne; Rosenzweig, Larry; Yi, Na Yi; Zachary, Wayne; OConnor, Bonnie

    2010-01-01

    Personnel from diverse ethnic and demographic backgrounds come together in both civilian and military healthcare systems, facing diagnoses that at one level are equalizers: coronary disease is coronary disease, breast cancer is breast cancer. Yet the expression of disease in individuals from different backgrounds, individual patient experience of disease as a particular illness, and interactions between patients and providers occurring in any given disease scenario, all vary enormously depending on the fortuity of the equation of "which patient happens to arrive in whose exam room." Previously, providers' absorption of lessons-learned depended on learning as an apprentice would when exposed over time to multiple populations. As a result, and because providers are often thrown into situations where communications falter through inadequate direct patient experience, diversity in medicine remains a training challenge. The questions then become: Can simulation and virtual training environments (VTEs) be deployed to short-track and standardize this sort of random-walk problem? Can we overcome the unevenness of training caused by some providers obtaining the valuable exposure to diverse populations, whereas others are left to "sink or swim"? This paper summarizes developing a computer-based VTE called TEACH (Training to Enable/Achieve Culturally Sensitive Healthcare). TEACH was developed to enhance healthcare providers' skills in delivering culturally sensitive care to African-American women with breast cancer. With an authoring system under development to ensure extensibility, TEACH allows users to role-play in clinical oncology settings with virtual characters who interact on the basis of different combinations of African American sub-cultural beliefs regarding breast cancer. The paper reports on the roll-out and evaluation of the degree to which these interactions allow providers to acquire, practice, and refine culturally appropriate communication skills and to

  18. Enhanced external and culturally sensitive attributions after extended intercultural contact.

    Science.gov (United States)

    Vollhardt, Johanna Ray

    2010-06-01

    This study examined the effect of close and extended intercultural contact on attributions for behaviour of out-group members. Specifically, it was hypothesized that extended intercultural contact would enhance the ability to make external and culturally sensitive attributions for ambiguous behaviour of out-group members, while decreasing the common tendency to overestimate internal factors. A content analysis of open-ended attributions supported these hypotheses, revealing that majority group members in Germany who had hosted an exchange student from another continent used significantly less internal and more external as well as culturally sensitive attributions to explain the behaviour described in critical intercultural incidents, compared to future hosts. The effect remained significant when controlling for perspective taking and prior intercultural experience. Moreover, the hypothesis was supported for scenarios describing different cultural groups (regardless of the exchange students' country of origin), suggesting a generalized effect. Problems of selection bias are discussed, and the importance of studying a range of positive outcomes of intercultural contact is emphasized.

  19. INTEGRATION OPPORTUNITIES OF MIGRANTS, WITH ESPECIAL REGARDS TO SENSITIZATION PROGRAMS

    Directory of Open Access Journals (Sweden)

    Krisztina DAJNOKI

    2017-06-01

    Full Text Available As a result of the migration wave appearing in summer 2015, the issue of immigrant integration has more often become conspicuous. Although a significant decline has been recorded in the number of immigrants, social-economic-labor market integration is still a challenge for experts and a task to be resolved. In our opinion, the key to the success of migration strategies and integration-aimed programs depends on the attitude and awareness of society (public opinion and – on the organizational level – the manager and future colleagues as well as on the organizational culture and the approach of a proper human resource expert. Besides adequate information, the recognition of international ‘best practices’ and the adaptation of operational diversity-management, one of the possible methods of facilitating integration is the utilization of sensitization trainings. The article introduces partial results of a questionnaire survey involving 220 employees with respect to attributes associated with migrants and emphasizing the peculiarity and significance of sensitization trainings.

  20. Components of cultural competence in three mental health programs.

    Science.gov (United States)

    Siegel, Carole; Haugland, Gary; Reid-Rose, Lenora; Hopper, Kim

    2011-06-01

    The aim of this study was to identify components of cultural competence in mental health programs developed for cultural groups by community and mental health professionals from these groups. Three programs were studied: a prevention program primarily serving African-American and Afro-Caribbean youth, a Latino adult acute inpatient unit, and a Chinese day treatment program in a community-based agency. Nine study-trained field researchers used a semistructured instrument that captures program genealogy, structure, processes, and cultural infusion. Program cultural elements were identified from field notes and from individual and group interviews of consumers and staff (N=104). A research-group consensus process with feedback from program staff was used to group elements by shared characteristics into the program components of cultural competence. Components included communication competencies (with use of colloquialisms and accepted forms of address); staff in culturally acceptable roles; culturally framed trust building (such as pairing youths with mentors), stigma reduction, friendly milieus (such as serving culturally familiar foods and playing music popular with the culture), and services; and peer, family, and community involvement (including use of peer counselors and mentors, hosting parent weekends, and linking clients with senior center and community services). Incorporating these components into any program in which underserved cultural populations are seen is recommended for improving cultural competence.

  1. Photodamage of the cells in culture sensitized with bilirubin

    Science.gov (United States)

    Kozlenkova, O. A.; Plavskaya, L. G.; Mikulich, A. V.; Leusenko, I. A.; Tretyakova, A. I.; Plavskii, V. Yu

    2016-08-01

    It has been shown that exposure to radiation of LED sources of light with an emission band maximum at about 465 and 520 nm having substantially identical damaging effects on animal cells in culture, that are in a logarithmic growth phase and preincubated with pigment. Photobiological effect is caused by photodynamic processes involving singlet oxygen generated by triplet excited sensitizer. Mono-exponential type dependence of cell survival on the energy dose indicates that it is bilirubin that acts as a sensitizer but not its photoproducts. The inclusion of bilirubin in the cells, where it is primarily localized in the mitochondria cells, it is accompanied by multiple amplification photochemical stability compared to pigment molecules bound with albumin

  2. Intercultural communication between patients and health care providers: an exploration of intercultural communication effectiveness, cultural sensitivity, stress, and anxiety.

    Science.gov (United States)

    Ulrey, K L; Amason, P

    2001-01-01

    Cultural diversity is becoming increasingly more important in the workplace. This is particularly true in health care organizations facing demographic shifts in the patients served and their families. This study serves to aid the development of intercultural communication training programs for health care providers by examining how cultural sensitivity and effective intercultural communication, besides helping patients, personally benefit health care providers by reducing their stress. Effective intercultural communication and cultural sensitivity were found to be related. Health care providers' levels of intercultural anxiety also were found to correlate with effective intercultural communication.

  3. Culture-bound syndrome and a culturally sensitive approach: from a viewpoint of medical anthropology.

    Science.gov (United States)

    Shimoji, A; Miyakawa, T

    2000-08-01

    Some aspects of the culture-bound syndrome are presented for discussion. From the psychiatric and medical anthropological viewpoints, kamidaari is described as an initiatory illness for seeing a shaman, and focus on clinical realities developing between different therapeutic subcultures in the same culture and the complementary practices of two epistemological ones, namely, the shamanistic and modern psychiatric system in the shamanistic climate. It is suggested that the culture-bound syndrome that reflects cultural influences on disease patterns and renders them difficult to place in a universal classificatory system should be seen as a vernacular bricolage or as tactics used by people within the web of their own local culture of origin. Therapists who treat patients in a cross-epistemological milieu should be aware of the subcultural-epistemological issues that may affect the clinical process. It should be recognized that, depending on the nature of a particular psychiatric crisis, the clinical encounter is straddling the boundaries of multiple clinical realities. At every stage in the clinical field, there is an intersection, consonance, or interruption of rejoinders in the open dialog by all those engaged in the clinical time. Aspects of climatic, culturally sensitive psychotherapy will be described, and the concept of the culture-bound syndrome will be reconsidered. Our approach could be seen as 'situation- and fudo-bound'.

  4. Sensitive periods for hormonal programming of the brain.

    Science.gov (United States)

    de Vries, Geert J; Fields, Christopher T; Peters, Nicole V; Whylings, Jack; Paul, Matthew J

    2014-01-01

    During sensitive periods, information from the external and internal environment that occurs during particular phases of development is relayed to the brain to program neural development. Hormones play a central role in this process. In this review, we first discuss sexual differentiation of the brain as an example of hormonal programming. Using sexual differentiation, we define sensitive periods, review cellular and molecular processes that can explain their restricted temporal window, and discuss challenges in determining the precise timing of the temporal window. We then briefly review programming effects of other hormonal systems and discuss how programming of these systems interact with sexual differentiation.

  5. Developing a culturally based cardiac rehabilitation program: the HELA study.

    Science.gov (United States)

    Look, Mele A; Kaholokula, Joseph Keawe; Carvhalo, Amy; Seto, Todd; de Silva, Mapuana

    2012-01-01

    Heart disease disproportionately affects Native Hawaiians and other Pacific people. In response, researchers proposed and communities endorsed, developing a cardiac rehabilitation (CR) program based on the hula, a Native Hawaiian dance form. The utilization of cultural practices in health interventions can improve outcomes and increase enrollment and retention, but requires sensitivity and understanding. This paper provides the conceptual framework and methods used for integration of multiple communities' perspectives to inform the design of a hula-based CR intervention. Specific strategies and processes were established to ensure the equity of scientific-clinical and patient- cultural knowledge and perspectives. Multiple methods were used and a flow diagram defined steps for the intervention development. Patient and cultural consultations provided information about the multidimensional benefits of hula and its use in a CR intervention. Clinical and scientific consultations provided specific guidelines for exercise prescription and patient monitoring. Integrating findings from all consultations identified important direction and requirements. Community-based participatory research (CBPR) principles guided a complex collaboration of multiple communities; although time consuming, inclusive consultations provided valuable information and relationships.

  6. Information and Communication Technologies – and Culturally Sensitive Systems

    Directory of Open Access Journals (Sweden)

    Nancy Michail

    2006-12-01

    Full Text Available This paper discusses the perceptions of Egyptian minority groups in relation to internet information technology with which they feel empowered to protect, affirm and communicate their oppressed existence, on local and global dimensions. The research employs qualitative methods and interpretive analysis, to focus on the use of Internet information technology tools by Egyptian minority groups, in particular, their online platforms and chat rooms, and the related issues associated with these practices and usages. The paper argues that cyberspace is used by specific minority groups in Egypt as a "gateway to freedom" in which it constitutes an ally to establish newly founded cyber identities that aide them to exercise their basic human rights of freedom of thought, speech and expression. The paper thus examines cyberspace a medium or tool for the carrying out of information exchange without the traditional fear of politics and power that is deeply engraved in the roots of the Egyptian culture. In this way, these minority groups are analysed as the newly conceived human information systems (HIS residing on Internet information technology and infrastructure. The paper proposes an adaptive and culturally sensitive model of human information systems as well as human information systems development life cycle (HISDLC to aid in establishing effective processes of information exchange and creation, hence assisting in the emancipation of conflicting parties residing in Egypt, elsewhere in the Middle East and globally.

  7. In vitro versus in vivo culture sensitivities: an unchecked assumption?

    Directory of Open Access Journals (Sweden)

    Prasad V

    2013-03-01

    Full Text Available No abstract available. Article truncated at 150 words. Case Presentation A patient presents to urgent care with the symptoms of a urinary tract infection (UTI. The urinalysis is consistent with infection, and the urine culture is sent to lab. In the interim, a physician prescribes empiric treatment, and sends the patient home. Two days later, the culture is positive for E. coli, resistant to the drug prescribed (Ciprofloxacin, Minimum Inhibitory Concentration (MIC 64 μg/ml, but attempts to contact the patient (by telephone are not successful. The patient returns the call two weeks later to say that the infection resolved without sequelae.Discussion Many clinicians have the experience of treatment success in the setting of known antibiotic resistance, and, conversely, treatment failure in the setting of known sensitivity. Such anomalies and empiric research described here forces us to revisit assumptions about the relationship between in vivo and in vitro drug responses. When it comes to the utility of microbiology…

  8. Developing culturally sensitive cancer genetics communication aids for African Americans.

    Science.gov (United States)

    Baty, Bonnie Jeanne; Kinney, Anita Yeomans; Ellis, Sara Marie

    2003-04-15

    The goal of this project was to develop educational materials to communicate genetic health information in a culturally sensitive manner. These materials were designed to communicate information about cancer risk, genetic testing options, and health management options in an African American kindred with a known BRCA1 mutation. Educational materials were pilot-tested in four African American focus groups varying in socioeconomic status and gender. The audiotaped focus groups consisted of presentation of the educational materials, followed by a feedback session led by an African American facilitator. Qualitative analysis of the focus group transcripts identified important themes and the educational materials were revised in response to the participants' suggestions. The products included a booklet and a flip chart for use in educational sessions. Focus group participants recommended a substantial reduction in technical detail, and recommended that information be personalized and made relevant to the lives of the target population. Other critical themes included the importance of building trust in the medical system and avoiding words and images that have strong negative associations in the African American community. Strategies that were successful included nontechnical images to explain genetic concepts, clip art images to energize and personalize word slides, vibrant color, identifiably African American figures, and the development of themes relevant to many African Americans. The use of these materials in an ongoing study offering BRCA1 counseling and testing to a large, rural Louisiana-based kindred will provide additional feedback about the effectiveness of the culturally tailored genetic education and counseling materials.

  9. Intensive Language and Culture Orientation Program for Japan.

    Science.gov (United States)

    Setliff, Rebecca J.; Taft, Lori A.

    The Language and Culture Institute of the University of Pittsburgh has developed a 13-week program of pre-assignment training for engineers given corporate assignments in Japan. The Institute offers the corporations three components in this intensive seminar: program administration, language training, and culture training. The program…

  10. A Method, Computer Program and System for Inferring Relations Between Cultural Specific Concepts in Two Cultures

    DEFF Research Database (Denmark)

    2013-01-01

    The present invention relates to a method, computer program and system for inferring relations between cultural specific concepts (CSC) in two cultures at least comprising the steps of - extracting and listing said cultural specific concepts (CSCs) and features of said CSCs from at least a first...

  11. Influence of Culture and Language Sensitive Physics on Science Attitude Enhancement

    Science.gov (United States)

    Morales, Marie Paz E.

    2015-01-01

    The study critically explored how culture and language sensitive curriculum materials in physics improve Pangasinan learners' attitude towards science. Their cultural dimensions, epistemological beliefs, and views on integration of culture and language in the teaching and learning process determined their cultural preference or profile. Design and…

  12. Influence of Culture and Language Sensitive Physics on Science Attitude Enhancement

    Science.gov (United States)

    Morales, Marie Paz E.

    2015-01-01

    The study critically explored how culture and language sensitive curriculum materials in physics improve Pangasinan learners' attitude towards science. Their cultural dimensions, epistemological beliefs, and views on integration of culture and language in the teaching and learning process determined their cultural preference or profile. Design and…

  13. Clinical exchange: one model to achieve culturally sensitive care.

    Science.gov (United States)

    Scholes, J; Moore, D

    2000-03-01

    This paper reports on a clinical exchange programme that formed part of a pre-registration European nursing degree run by three collaborating institutions in England, Holland and Spain. The course included: common and shared learning including two summer schools; and the development of a second language before the students went on a three-month clinical placement in one of the other base institutions' clinical environments. The aim of the course was to enable students to become culturally sensitive carers. This was achieved by developing a programme based on transcultural nursing principles in theory and practice. Data were gathered by interview, focus groups, and questionnaires from 79 exchange students, fostering the strategies of illuminative evaluation. The paper examines: how the aims of the course were met; the factors that inhibited the attainment of certain goals; and how the acquisition of a second language influenced the students' learning about nursing. A model is presented to illustrate the process of transformative learning from the exchange experience.

  14. MP.EXE Microphone pressure sensitivity calibration calculation program

    DEFF Research Database (Denmark)

    Rasmussen, Knud

    1999-01-01

    MP.EXE is a program which calculates the pressure sensitivity of LS1 microphones as defined in IEC 61094-1, based on measurement results performed as laid down in IEC 61094-2.A very early program was developed and written by K. Rasmussen. The code of the present heavily extended version is written...... by E.S. Olsen.The present manual is written by K.Rasmussen and E.S. Olsen....

  15. A cross-cultural, long-term outcome evaluation of the ISTAR Comprehensive Stuttering Program across Dutch and Canadian adults who stutter.

    NARCIS (Netherlands)

    Langevin, M.; Huinck, W.J.; Kully, D.; Peters, H.F.M.; Lomheim, H.; Tellers, M.

    2006-01-01

    There is a need to evaluate the effectiveness of stuttering treatment programs delivered in domestic and international contexts and to determine if treatment delivered internationally is culturally sensitive. Evaluation of the effectiveness of the ISTAR Comprehensive Stuttering Program (CSP) within

  16. A cross-cultural, long-term outcome evaluation of the ISTAR Comprehensive Stuttering Program across Dutch and Canadian adults who stutter.

    NARCIS (Netherlands)

    Langevin, M.; Huinck, W.J.; Kully, D.; Peters, H.F.M.; Lomheim, H.; Tellers, M.

    2006-01-01

    There is a need to evaluate the effectiveness of stuttering treatment programs delivered in domestic and international contexts and to determine if treatment delivered internationally is culturally sensitive. Evaluation of the effectiveness of the ISTAR Comprehensive Stuttering Program (CSP) within

  17. When I grow up: Culturally sensitive graphic design explorations

    OpenAIRE

    Schutte, Grace

    2013-01-01

    With a global village that is growing and a world that is getting smaller it becomes evermore important for graphic designers to successfully cross cultural borders, yet this is easier said than done. My theoretical work aims at making these cross-cultural design experiences easier for graphic designers, as well as creating higher awareness of the differences that exist within cultural constructions. An amalgamation of design practices, cultural and anthropological research, the theory e...

  18. Student nurses' experiences of living and studying in a different culture to their own and the development of cultural sensitivity

    DEFF Research Database (Denmark)

    Ruddock, Heidi

    With the increase of culturally diverse people residing in Denmark, it has become imperative to provide student nurses with knowledge and skills that will enable them to become culturally sensitive in order interact effectively with clients from culturally diverse backgrounds. The aim of this study...... was to explore whether student nurses develop cultural sensitivity as a consequence of living and studying in a culture that is different from their own. Seven Danish student nurses who had participated in student exchanges in Jamaica, Australia, Malta and Greenland took part in this study. A qualitative...... characteristics of openness and flexibility and support networks facilitated the students transition and adjustment to the host culture. Reflection on their experiences with students from a similar background to themselves and clinical mentors from the host culture assisted the students in their understanding...

  19. Development of Cross-cultural Sensitivity in Business Courses: The Culturelog.

    Science.gov (United States)

    Starr-Glass, David

    1995-01-01

    Foreign students in a business administration and marketing program in Israel are required to keep a journal noting observations of cultural differences and examine them in relation to their own cultures and the Israeli culture. Non-Americans also note cross-cultural concepts raised by their American textbooks. The log helps students perceive,…

  20. Developing cultural sensitivity: nursing students' experiences of a study abroad programme.

    Science.gov (United States)

    Ruddock, Heidi C; Turner, de Sales

    2007-08-01

    This paper is a report of a study to explore whether having an international learning experience as part of a nursing education programme promoted cultural sensitivity in nursing students. background: Many countries are becoming culturally diverse, but healthcare systems and nursing education often remain mono-cultural and focused on the norms and needs of the majority culture. To meet the needs of all members of multicultural societies, nurses need to develop cultural sensitivity and incorporate this into caregiving. A Gadamerian hermeneutic phenomenological approach was adopted. Data were collected in 2004 by using in-depth conversational interviews and analysed using the Turner method. Developing cultural sensitivity involves a complex interplay between becoming comfortable with the experience of making a transition from one culture to another, making adjustments to cultural differences, and growing personally. Central to this process was the students' experience of studying in an unfamiliar environment, experiencing stress and varying degrees of culture shock, and making a decision to take on the ways of the host culture. These actions led to an understanding that being sensitive to another culture required being open to its dynamics, acknowledging social and political structures, and incorporating other people's beliefs about health and illness. The findings suggest that study abroad is a useful strategy for bridging the theory-practice divide. However, further research is needed with larger and more diverse students to test the generalizability of the findings. Longitudinal research is also needed to assess the impact of study abroad programmes on the deliver of culturally sensitive care.

  1. [Detection of cancer, sensitivity of the test and sensitivity of the screening program].

    Science.gov (United States)

    Launoy, G; Duffy, S W; Prevost, T C; Bouvier, V

    1998-11-01

    In assessment of screening for cancer, no distinction is usually made between the sensitivity of the screening test (St) and the sensitivity of the screening program (Sp). This paper was aimed to distinguish meaning, method for assessment and interest for each of them, and to determine their relationship. Sensitivity of the screening program can be directly assessed with data from on-going trials whilst assessment of sensitivity of screening test requires modelisation techniques, especially for assessing the mean duration of the preclinical phase of cancer. Assuming an exponential distribution of this duration, lambda as the time parameter, a mathematical relation between St and Sp is suggested as follows: [formula: see text] with r being the interval between two screening tests. The implementation of this equation with data from a mass-screening program for colorectal cancer in the department of Calvados allowed us to investigate the influence of the mean preclinical phase and the interval between two screening tests on the value of the sensitivity of the screening procedure. Such a modelisation could be useful in the development of a rational screening policy.

  2. "Fools Rush In": Developing Cross-Cultural Sensitivity Using Film-Based Group Projects.

    Science.gov (United States)

    Tidwell, Charles H., Jr.

    Although role playing games and self-awareness surveys are typical methods of developing cross-cultural sensitivity, this presentation advocates the use small group projects focusing on feature films such as "Fools Rush In" as an effective class or training exercise to develop sensitivity to other cultures. Despite some disadvantages…

  3. The relationship between the nursing environment and delivering culturally sensitive perinatal hospice care.

    Science.gov (United States)

    Mixer, Sandra J; Lindley, Lisa; Wallace, Heather; Fornehed, Mary Lou; Wool, Charlotte

    2015-09-01

    Wide variations exist among perinatal hospices, and barriers to perinatal palliative care exist at the healthcare level. Research in the area of culturally sensitive perinatal palliative care has been scarce, a gap which this study addresses. To evaluate the relationship between the nurse work environment and the delivery of culturally sensitive perinatal hospice care. This retrospective, correlational study used data from the National Home and Hospice Care Survey, which includes a nationally representative sample of hospice care providers. A multivariate logistic regression model was used to estimate the relationship between the delivery of culturally sensitive care and the nurse work environment. Accreditation, teaching status, and baccalaureate-prepared registered nurse staff had an impact on the provision of culturally sensitive perinatal care Conclusions: The hospice and nursing unit environments, specifically in regards to education and technology, may be important contributors to the delivery of culturally sensitive care.

  4. Updated Results from the COS Spectroscopic Sensitivity Monitoring Program

    Science.gov (United States)

    Osten, Rachel A.; Massa, Derck; Bostroem, Azalee; Aloisi, Alessandra; Proffitt, Charles

    2011-06-01

    We report updated results from the Cosmic Origins Spectrograph spectroscopic sensitivity monitoring programs utilizing data taken through the end of Cycle 17 and beginning of Cycle 18. Earlier results (reported in Osten et al. 2010) had indicated a wavelengthdependent decline of the FUV sensitivity which was worse at longer wavelengths. Since mid-March 2010, the rate of this sensitivity decline has become much smaller and mostly wavelength independent, and the rate of decline is now between 2 and 5%/year for all Far-Ultraviolet (FUV) gratings with sufficient signal to characterize. The characteristics of the FUV sensitivity decline are consistent with degradation of the quantum efficiency of the CsI photocathode of the FUV detector. The initial steep decline may have been caused by water vapor outgassing after COS's installation, while the subsequent decline may be due to exposure to ambient atomic oxygen present at HST's orbital altitude. New FUV Time-Dependent Sensitivity (TDS) reference files have been delivered to correct the pipeline flux calibration, however, even after the application of these TDS corrections there remain discrepancies in the absolute flux calibration which appear to depend on central wavelength and FP-POS, and can be up to 5-10%. Further investigation reveals that some of this discrepancy may be due to additional sensitivity degradation during initial on-orbit operations. As reported in Osten et al. (2010), the two NUV bare-aluminum gratings (G225M and G285M) are also showing sensitivity declines, which appear to continue trends seen during ground testing, and which may be due to ongoing evolution of an oxide layer. In contrast, the throughputs of the NUV gratings coated with MgF2 (G185M and G230L) remain stable, showing little to no sensitivity decline. The NUV bare-aluminum sensitivity decline appears to be a continuing trend from that seen on the ground.

  5. Response to Marie Paz Morales' ``Influence of culture and language sensitive physics on science attitude achievement''

    Science.gov (United States)

    Cole, Mikel Walker

    2015-12-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript.

  6. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  7. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  8. Cultural Sensitivity in ATOD Agencies: Administrator and Staff Perceptions in the Hispanic Heartland

    Directory of Open Access Journals (Sweden)

    David R. Hodge

    2000-12-01

    Full Text Available Administrator and staff perceptions (N = 72 of alcohol, tobacco, and other drugs (ATOD agency cultural sensitivity were explored in a predominantly Hispanic rural area with elevated levels of acculturation and high ATOD usage. While providers generally agreed that a relatively moderate need existed for training related to cultural issues, a more nuanced picture emerged in the purview of culturally- related barriers. Administrators viewed the lack of appropriate interpreters and language as a greater barrier than did the staff. Administrators also held higher perceptions of agencies’ cultural competency. The overall high assessment of cultural sensitivity may result from the substantial number of Latino providers.

  9. A Computer Program for Assessing Nuclear Safety Culture Impact

    Energy Technology Data Exchange (ETDEWEB)

    Han, Kiyoon; Jae, Moosung [Hanyang Univ., Seoul (Korea, Republic of)

    2014-10-15

    Through several accidents of NPP including the Fukushima Daiichi in 2011 and Chernobyl accidents in 1986, a lack of safety culture was pointed out as one of the root cause of these accidents. Due to its latent influences on safety performance, safety culture has become an important issue in safety researches. Most of the researches describe how to evaluate the state of the safety culture of the organization. However, they did not include a possibility that the accident occurs due to the lack of safety culture. Because of that, a methodology for evaluating the impact of the safety culture on NPP's safety is required. In this study, the methodology for assessing safety culture impact is suggested and a computer program is developed for its application. SCII model which is the new methodology for assessing safety culture impact quantitatively by using PSA model. The computer program is developed for its application. This program visualizes the SCIs and the SCIIs. It might contribute to comparing the level of the safety culture among NPPs as well as improving the management safety of NPP.

  10. The relationship between cultural sensitivity and perceived stress among nurses working with foreign patients.

    Science.gov (United States)

    Uzun, Özge; Sevinç, Sibel

    2015-12-01

    To determine the relationship between cultural sensitivity and perceived stress of nurses working at Kilis State Hospital. As foreigners live in and visit Turkey for various reasons, it is essential to provide culturally appropriate healthcare. Descriptive and cross-sectional design. This study was implemented at the State Hospital in Kilis on the southeast border of Turkey, between June-July 2014. The study sample consisted of 120 nurses. Data collection tools included a questionnaire about the socio-demographic and professional characteristics of participants, the Chen and Starosta's Intercultural Sensitivity Scale, and Perceived Stress Scale. The average score for nurse cultural sensitivity was 84·32 (SD, 11·40) and the average score for perceived stress was 27·97 (SD, 7·32), corresponding to a medium level. We identified negative correlation between cultural sensitivity and perceived stress. Nurses working at Kilis State Hospital have a medium level of cultural sensitivity and perceived stress, and cultural sensitivity tended to be affected by perceived stress. This study suggests that training programmes for cultural sensitivity and stress management should be available for nurses. Furthermore, patient care plans should be adapted to consider different cultural backgrounds of patients. These findings should be considered when designing nurses' education and continuing education programmes. © 2015 John Wiley & Sons Ltd.

  11. Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth

    Energy Technology Data Exchange (ETDEWEB)

    Harrill, Joshua A.; Freudenrich, Theresa M.; Robinette, Brian L.; Mundy, William R., E-mail: mundy.william@epa.gov

    2011-11-15

    There is a need for rapid, efficient and cost-effective alternatives to traditional in vivo developmental neurotoxicity testing. In vitro cell culture models can recapitulate many of the key cellular processes of nervous system development, including neurite outgrowth, and may be used as screening tools to identify potential developmental neurotoxicants. The present study compared primary rat cortical cultures and human embryonic stem cell-derived neural cultures in terms of: 1) reproducibility of high content image analysis based neurite outgrowth measurements, 2) dynamic range of neurite outgrowth measurements and 3) sensitivity to chemicals which have been shown to inhibit neurite outgrowth. There was a large increase in neurite outgrowth between 2 and 24 h in both rat and human cultures. Image analysis data collected across multiple cultures demonstrated that neurite outgrowth measurements in rat cortical cultures were more reproducible and had higher dynamic range as compared to human neural cultures. Human neural cultures were more sensitive than rat cortical cultures to chemicals previously shown to inhibit neurite outgrowth. Parallel analysis of morphological (neurite count, neurite length) and cytotoxicity (neurons per field) measurements were used to detect selective effects on neurite outgrowth. All chemicals which inhibited neurite outgrowth in rat cortical cultures did so at concentrations which did not concurrently affect the number of neurons per field, indicating selective effects on neurite outgrowth. In contrast, more than half the chemicals which inhibited neurite outgrowth in human neural cultures did so at concentrations which concurrently decreased the number of neurons per field, indicating that effects on neurite outgrowth were secondary to cytotoxicity. Overall, these data demonstrate that the culture models performed differently in terms of reproducibility, dynamic range and sensitivity to neurite outgrowth inhibitors. While human neural

  12. Evolutionary Model to Traditional Culture and Program Organization

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jing-xiao; JIN Wei-xing; YANG De-qin

    2006-01-01

    To study the relationship between the evolutions of Chinese Traditional Culture (CTC) and program organization, an outline of the CTC is generalized by reviewing literature, and which is also compartmentalized into two aspects according to economic philosophy views: traditional philosophy aspect and value judgment. Based on three dimensions, which are the philosophy aspect (P), program organization model (P), and value judgment from economic philosophy views (V), and this evolution sequence, the CTC's influence on the program organization model in the evolution is discussed; then the cultural spatial evolution model for program organization based on the three dimensions (PPV) is constructed. From analyzing the plane matrix of P-P and empirical investigating on the organizational model of construction enterprises, it is found that the ancient Chinese government organizational model still has prevailing influence on the modern program organizational model in China.

  13. Spanish-speaking patients' satisfaction with clinical pharmacists' communication skills and demonstration of cultural sensitivity.

    Science.gov (United States)

    Kim-Romo, Dawn N; Barner, Jamie C; Brown, Carolyn M; Rivera, José O; Garza, Aida A; Klein-Bradham, Kristina; Jokerst, Jason R; Janiga, Xan; Brown, Bob

    2014-01-01

    OBJECTIVE To assess Spanish-speaking patients' satisfaction with their clinical pharmacists' communication skills and demonstration of cultural sensitivity, while controlling for patients' sociodemographic, clinical, and communication factors, as well as pharmacist factors, and to identify clinical pharmacists' cultural factors that are important to Spanish-speaking patients. DESIGN Cross-sectional study. SETTING Central Texas during August 2011 to May 2012. PARTICIPANTS Spanish-speaking patients of federally qualified health centers (FQHCs). MAIN OUTCOME MEASURE(S) A Spanish-translated survey assessed Spanish-speaking patients' satisfaction with their clinical pharmacists' communication skills and demonstration of cultural sensitivity. RESULTS Spanish-speaking patients (N = 101) reported overall satisfaction with their clinical pharmacists' communication skills and cultural sensitivity. Patients also indicated that pharmacists' cultural rapport (e.g., ability to speak Spanish, respectfulness) was generally important to Spanish speakers. Multiple linear regression analyses showed that cultural rapport was significantly related to satisfaction with pharmacists' communication skills and demonstration of cultural sensitivity. CONCLUSION Overall, patients were satisfied with pharmacists' communication skills and cultural sensitivity. Patient satisfaction initiatives that include cultural rapport should be developed for pharmacists who provide care to Spanish-speaking patients with limited English proficiency.

  14. Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models.

    Directory of Open Access Journals (Sweden)

    Direk Limmathurotsakul

    Full Text Available BACKGROUND: Culture remains the diagnostic gold standard for many bacterial infections, and the method against which other tests are often evaluated. Specificity of culture is 100% if the pathogenic organism is not found in healthy subjects, but the sensitivity of culture is more difficult to determine and may be low. Here, we apply Bayesian latent class models (LCMs to data from patients with a single Gram-negative bacterial infection and define the true sensitivity of culture together with the impact of misclassification by culture on the reported accuracy of alternative diagnostic tests. METHODS/PRINCIPAL FINDINGS: Data from published studies describing the application of five diagnostic tests (culture and four serological tests to a patient cohort with suspected melioidosis were re-analysed using several Bayesian LCMs. Sensitivities, specificities, and positive and negative predictive values (PPVs and NPVs were calculated. Of 320 patients with suspected melioidosis, 119 (37% had culture confirmed melioidosis. Using the final model (Bayesian LCM with conditional dependence between serological tests, the sensitivity of culture was estimated to be 60.2%. Prediction accuracy of the final model was assessed using a classification tool to grade patients according to the likelihood of melioidosis, which indicated that an estimated disease prevalence of 61.6% was credible. Estimates of sensitivities, specificities, PPVs and NPVs of four serological tests were significantly different from previously published values in which culture was used as the gold standard. CONCLUSIONS/SIGNIFICANCE: Culture has low sensitivity and low NPV for the diagnosis of melioidosis and is an imperfect gold standard against which to evaluate alternative tests. Models should be used to support the evaluation of diagnostic tests with an imperfect gold standard. It is likely that the poor sensitivity/specificity of culture is not specific for melioidosis, but rather a generic

  15. Outsiders in nursing education: cultural sensitivity in clinical education.

    Science.gov (United States)

    Debrew, Jacqueline Kayler; Lewallen, Lynne Porter; Chun, Edna

    2014-01-01

    Cultural competence is a stated value of nursing and nursing education. However, some institutional and traditional practices in nursing education can unintentionally impede nurses from achieving cultural competence. Both the literature and interviews with nurse educators show that despite educators' intentions to treat all students the same, nontraditional students may feel singled out and may in fact be singled out for closer scrutiny because of their difference from the demographic norms of nursing students. To ensure that the nursing profession reflects the composition of the patient population it serves, nurse educators must first acknowledge the Eurocentric culture of nursing education and, then, work to change the environment in which students are recruited, learn, and take on the role of beginning practicing nurses.

  16. Incorporating Cultural Competence & Youth Program Volunteers: A Literature Review

    Directory of Open Access Journals (Sweden)

    Julianne Smith

    2016-12-01

    Full Text Available The increasing diversity of youth in the United States necessitates a shift in the ways that youth services and programming are designed and implemented. This article examines existing scholarship on developing the cultural competency of volunteers in youth development programs in an effort to improve 4-H YDP protocol. Drawing from a diverse, interdisciplinary range of peer-reviewed, academic articles, this literature review plots out recent pedagogical trends, theoretical concepts, and empirical studies dealing with the cultural competence of service workers and mentors interacting with youth. Based on a synthesis of the findings, this paper presents guiding principles for increasing cultural competence of youth program design through both training and organizational changes.

  17. Program for Culture and Conflict Studies, web page capture

    OpenAIRE

    Naval Postgraduate School (U.S.)

    2014-01-01

    web page capture from the NPS website The Program for Culture and Conflict Studies (CCS) is premised on the belief that the United States must understand the cultures and societies of the world to effectively interact with local people. It is dedicated to the study of anthropological, ethnographic, social, political, and economic data to inform U.S. policies at both the strategic and operational levels.

  18. Ethnicity and Diet of Children: Development of Culturally Sensitive Measures

    Science.gov (United States)

    Bruss, Mozhdeh B.; Applegate, Brooks; Quitugua, Jackie; Palacios, Rosa T.; Morris, Joseph R.

    2007-01-01

    Obesity is a growing global concern. Examining dietary habits of individuals can facilitate the development of important prevention approaches, which are needed to decrease the incidence of obesity and other related diseases and improve quality of life indices. Because food preferences and dietary habits vary across cultures, it is essential that…

  19. Cultural Sensitivity: The Key to Teaching Global Business.

    Science.gov (United States)

    Timm, Judee A.

    2003-01-01

    More ethical practices in business begin with ethical training in business schools. International business education classes can compare corporate codes and actual behavior; explore the role of cultural differences in values, principles, and standards; and analyze ethical dilemmas in a global environment. (SK)

  20. Culturally Sensitive Mentoring for Asian International Students in Counseling Psychology

    Science.gov (United States)

    Park-Saltzman, Jeeseon; Wada, Kaori; Mogami, Tamiko

    2012-01-01

    With growing attention to the internationalization of counseling psychology in the past decade, discussion on effective training of international students is much-needed. In order to provide effective mentorship to international students, the mentor needs to be aware of specific challenges faced by international students and cultural differences…

  1. Incorporating Cultural Sensitivity into Interactive Entertainment-Education for Diabetes Self-Management Designed for Hispanic Audiences.

    Science.gov (United States)

    Kline, Kimberly N; Montealegre, Jane R; Rustveld, Luis O; Glover, Talar L; Chauca, Glori; Reed, Brian C; Jibaja-Weiss, Maria L

    2016-06-01

    Diabetes self-management education can improve outcomes in adults with Type 2 diabetes mellitus (T2DM). However, Hispanics, a group that carries a large burden of disease, may not participate in diabetes education programs. Audience engagement with entertainment-education has been associated with improved health education outcomes and may engage and empower Hispanic users to active self-care. Successful use of entertainment-education relies on the use of characters and situations with whom the viewers can feel some sense of involvement and for Hispanic audiences is encouraged when storylines and characters are culturally sensitive. In this study, we used a mixed methods approach that included descriptive statistics of closed-ended and content analysis of open-ended questions to measure the cultural sensitivity of the telenovela portion of a novel technology-based application called Sugar, Heart, and Life (SHL). Specifically, we analyzed the responses of 123 male and female patients diagnosed with uncontrolled T2DM to determine viewer involvement with characters and situations in the telenovela, viewer perceived self-efficacy in following recommendations, as well as viewer satisfaction with the program. Our findings indicate that the SHL application achieved its goal of creating a user-friendly program that depicted realistic, culturally sensitive characters and storylines that resonated with Hispanic audiences and ultimately fostered perceived self-efficacy related to following recommendations given about healthy lifestyle changes for diabetes self-management. These findings suggest that the SHL application is a culturally sensitive health education intervention for use by Hispanic male and female individuals that may empower them in self-management of T2DM.

  2. Cultural differences define diagnosis and genomic medicine practice: implications for undiagnosed diseases program in China.

    Science.gov (United States)

    Duan, Xiaohong; Markello, Thomas; Adams, David; Toro, Camilo; Tifft, Cynthia; Gahl, William A; Boerkoel, Cornelius F

    2013-09-01

    Despite the current acceleration and increasing leadership of Chinese genetics research, genetics and its clinical application have largely been imported to China from the Occident. Neither genetics nor the scientific reductionism underpinning its clinical application is integral to the traditional Chinese worldview. Given that disease concepts and their incumbent diagnoses are historically derived and culturally meaningful, we hypothesize that the cultural expectations of genetic diagnoses and medical genetics practice differ between the Occident and China. Specifically, we suggest that an undiagnosed diseases program in China will differ from the recently established Undiagnosed Diseases Program at the United States National Institutes of Health; a culturally sensitive concept will integrate traditional Chinese understanding of disease with the scientific reductionism of Occidental medicine.

  3. Cultural context and school counseling: Cultural sensitivity to advocate for social justice

    OpenAIRE

    Tatar, Moshé

    2012-01-01

    In this paper the relevance of understanding the different meanings of culture in the counseling profession is presented. Two approaches to the concept of culture as they relate to counseling are suggested: the first approach stresses the organisational culture of the institution where the counselor works; the second —the multicultural approach— calls for the complex recognition of the variety of ethnic cultural backgrounds of those involved in the counseling situation. Professional practices...

  4. Cultural context and school counseling: Cultural sensitivity to advocate for social justice

    OpenAIRE

    Moshé Tatar

    2008-01-01

    In this paper the relevance of understanding the different meanings of culture in the counseling profession is presented. Two approaches to the concept of culture as they relate to counseling are suggested: the first approach stresses the organisational culture of the institution where the counselor works; the second —the multicultural approach— calls for the complex recognition of the variety of ethnic cultural backgrounds of those involved in the counseling situation. Professional practices...

  5. Sensitivity Increases for the TITAN Decay Spectroscopy Program

    Directory of Open Access Journals (Sweden)

    Leach K.G.

    2015-01-01

    Full Text Available The TITAN facility at TRIUMF has recently initiated a program of performing decay spectroscopy measurements in an electron-beam ion-trap (EBIT. The unique environment of the EBIT provides backingfree storage of the radioactive ions, while guiding charged decay particles from the trap centre via the strong magnetic field. This measurement technique is able to provide a significant increase in detection sensitivity for photons which result from radioactive decay. A brief overview of this device is presented, along with methods of improving the signal-to-background ratio for photon detection by reducing Compton scattered events, and eliminating vibrational noise.

  6. Sensitivity Increases for the TITAN Decay Spectroscopy Program

    CERN Document Server

    Leach, K G; Grossheim, A; Andreoiu, C; Dilling, J; Frekers, D; Good, M; Seeraji, S

    2014-01-01

    The TITAN facility at TRIUMF has recently initiated a program of performing decay spectroscopy measurements in an electron-beam ion-trap (EBIT). The unique environment of the EBIT provides backing-free storage of the radioactive ions, while guiding charged decay particles from the trap centre via the strong magnetic field. This measurement technique is able to provide a significant increase in detection sensitivity for photons which result from radioactive decay. A brief overview of this device is presented, along with methods of improving the signal-to-background ratio for photon detection by reducing Compton scattered events, and eliminating vibrational noise.

  7. Cultural Sensitiveness of School Goals and Students’ Failure in Turkey

    Directory of Open Access Journals (Sweden)

    Ismet Sahin

    2006-06-01

    Full Text Available Education is the means by which society provides for the transmission or advancement of its culture and it is formally done at schools that are the arena of human interaction aimed at producing learning. But some people in that interaction aimed at producing learning cannot achieve as much as the others due to some social or individual factors especially when the society is not homogeneous in terms of culture, language, etc.All cultures do not require the same kinds of knowledge and all may have distinct goals and expectations in education. This study aims at presenting the consensus and conflict in perspectives of students of different ethnic origins on general goals of education and expectations from schools in East and Southeast Turkey. The results will be used to generate a rationale to assume that the failure of students in East and Southeast Turkey where majority of population is ethnically diverse, may be because of the lack of divergent goals and expectations set for school curriculum or that the failure of students is dependent on some other factors except the unique school curriculum unresponsive to cultural or ethnic diversity. For this purpose, the goals of general education (1973, Law number 1739, Item number 2, and school expectations developed by House (1973 were prepared as questionnaire items, piloted, validated and administered to 9373 secondary school students in east and southeast Turkey. The findings of this study were that the students of different ethnic origins value the goals and expectations set for school curriculum in Turkey in significantly different ways.

  8. Dopamine-System Genes and Cultural Acquisition: The Norm Sensitivity Hypothesis

    Science.gov (United States)

    Kitayama, Shinobu; King, Anthony; Hsu, Ming; Liberzon, Israel; Yoon, Carolyn

    2016-01-01

    Previous research in cultural psychology shows that cultures vary in the social orientation of independence and interdependence. To date, however, little is known about how people may acquire such global patterns of cultural behavior or cultural norms. Nor is it clear what genetic mechanisms may underlie the acquisition of cultural norms. Here, we draw on recent evidence for certain genetic variability in the susceptibility to environmental influences and propose a norm sensitivity hypothesis, which holds that people acquire culture, and rules of cultural behaviors, through reinforcement-mediated social learning processes. One corollary of the hypothesis is that the degree of cultural acquisition should be influenced by polymorphic variants of genes involved in dopaminergic neural pathways, which have been widely implicated in reinforcement learning. We reviewed initial evidence for this prediction and discussed challenges and directions for future research. PMID:28491931

  9. Beyond Factionalism? Cultural and Children's Programs on Palestinian Satellite TV

    NARCIS (Netherlands)

    M.O. AlMoghayer (Mohammed)

    2016-01-01

    markdownabstractThis study examines the production of Palestinian satellite television in the contemporary era. The focus is on cultural and children’s programs of two key stations, the Hamas-based Al Aqsa Satellite Channel (ASC) and the Fatah-based Palestine Satellite Channel (PSC). The study inter

  10. Rationale for the Cultural Construction of School Mental Health Programming

    Science.gov (United States)

    Arora, Prerna G.; Nastasi, Bonnie K.; Leff, Stephen S.

    2017-01-01

    The implementation of evidence-based psychological programming to meet the needs of a global population has been impeded by the translation of theories and research findings across populations and settings without due consideration of cultural factors. The purpose of this article is to discuss the rationale for use of partnership-based methods in…

  11. Fulbright-Hays Seminars Abroad Program June 23-July 26, 1993. Brazilian History and Culture Program.

    Science.gov (United States)

    Department of Education, Washington, DC. Div. of International Education.

    This document consists of 16 papers on aspects of Brazilian culture, history, and geography prepared by participants in the Fulbright Hays Seminars Abroad Program in Brazil in 1993. The papers are: (1) "Cordel Literature: A Window on the History and Culture of Brazil" (Juan Barroso VIII); (2) "Connections: Public Images of Indians and Brazil's…

  12. Learning Tolerance: The Impact of Comparative Politics Courses on Levels of Cultural Sensitivity

    Science.gov (United States)

    Brooks, D. Christopher

    2005-01-01

    In addition to exposing students to basic concepts, theories, and ideas, teachers of comparative politics often claim to foster and promote values of tolerance and cultural sensitivity through exposure to the histories, cultures, and societies of cases from around the world. This claim, however, has been largely speculative and unsupported by any…

  13. Sensitivity of Students to the Natural Environment, Animals, Social Problems and Cultural Heritage

    Science.gov (United States)

    Kurtdede Fidan, Nuray

    2016-01-01

    The study aims to determine the sensitivity levels of fourth-grade students to the natural environment, animals, social concerns and cultural heritage. Besides, it has been investigated whether some personal characteristics of the students have differentiating effect on the views related to the sensitivity to the natural environment, animals,…

  14. THE GROWTH OF ASIBI STRAIN YELLOW FEVER VIRUS IN TISSUE CULTURES. I. SENSITIVITY AND CAPACITY OF TISSUE CULTURES

    Science.gov (United States)

    directed to HeLa cells . The following results were obtained: Of those cultures that were susceptible, three different patterns of dose response were...obtained that were interpreted as different possible manifestations of interference. HeLa cells , which were among the least sensitive to low infection

  15. Assessing the cultural in culturally sensitive printed patient-education materials for Chinese Americans with type 2 diabetes.

    Science.gov (United States)

    Ho, Evelyn Y; Tran, Henrietta; Chesla, Catherine A

    2015-01-01

    Type 2 diabetes affects Chinese Americans at an alarming rate. To address this health disparity, research in the area of cultural sensitivity and health literacy provides useful guidelines for creating culturally appropriate health education. In this article, we use discourse analysis to examine a group of locally available, Chinese- and English-language diabetes print documents from a surface level and deep structure level of culture. First, we compared these documents to research findings about printed health information to determine whether and how these documents apply current best practices for health literacy and culturally appropriate health communication. Second, we examined how diabetes as a disease and diabetes management is being constructed. The printed materials addressed surface level culture through the use of Chinese language, pictures, foods, and exercises. From a deeper cultural level, the materials constructed diabetes management as a matter of measurement and control that contrasted with previous research suggesting an alternative construction of balance. A nuanced assessment of both surface and deeper levels of culture is essential for creating health education materials that are more culturally appropriate and can lead to increased health literacy and improved health outcomes.

  16. INEEL Cultural Resource Management Program Annual Report - 2004

    Energy Technology Data Exchange (ETDEWEB)

    Clayton F. Marler

    2005-01-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The Idaho National Engineering and Environmental Laboratory Site is located in southeastern Idaho, and is home to vast numbers and a wide variety of important cultural resources representing at least 13,000-year span of human occupation in the region. These resources are nonrenewable, bear valuable physical and intangible legacies, and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these resources with the management and ongoing operation of an active scientific laboratory, while also cleaning up the waste left by past programs and processes. The Department of Energy Idaho Operations Office has administrative responsibility for most of the Site, excluding lands and resources managed by the Naval Reactors Facility and (in 2004) Argonne National Laboratory-West. The Department of Energy is committed to a cultural resource program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative requirements. This annual report is an overview of Cultural Resource Management Program activities conducted during Fiscal Year 2004 and is intended to be both informative to external stakeholders and to serve as a planning tool for future cultural resource management work to be conducted on the Site.

  17. Culturally sensitive health counseling to prevent lifestyle-related diseases in Japan.

    Science.gov (United States)

    Marutani, Miki; Miyazaki, Misako

    2010-09-01

    This study explored the methods that are used by public health nurses to provide culturally sensitive health counseling to elderly Japanese farmers in order to motivate them to adopt healthy behaviors. Fourteen elderly farmers (eight men and six women) from three rural communities underwent health counseling and then changed their habits to prevent lifestyle-related diseases. Qualitative and inductive analyses were conducted to determine the effects of the culturally sensitive counseling. Five methods for providing culturally sensitive counseling were identified: (i) showing an interest in, and respect for, the local culture; (ii) stimulating the participants' awareness of the health risks inherited in their local cultural practices through the use of familiar examples; (iii) accepting and understanding the participants' ambivalence about their local culture; (iv) connecting the reasons for the participants to change their lifestyle with their local culture; and (v) adjusting the health-promoting behaviors of the participants to fit their local culture. Public health nurses should consider the pride that elderly farmers have in their background and their resistance to change and use these factors to point out the discrepancies in their lifestyle and promote more quality-of-life-oriented and practical self-care behaviors.

  18. Cultured stem cells are sensitive to gravity changes

    Science.gov (United States)

    Buravkova, L. B.; Romanov, Yu. A.; Konstantinova, N. A.; Buravkov, S. V.; Gershovich, Yu. G.; Grivennikov, I. A.

    2008-09-01

    Stem and precursor cells play an important role in development and regeneration. The state of these cells is regulated by biochemical substances, mechanical stimuli and cellular interactions. To estimate gravity effects we used two types of cultured stem cells: human mesenchymal stromal cells (hMSCs) from bone marrow and mice embryonic stem (mESC) line R1. Gravity changes were simulated by long-term (4-7 days) slow clinorotation and leaded to decreased hMSC proliferation, changes of cell morphology and modified F-actin cytoskeleton. We did not find the shifts in cell phenotype except for decreased expression of HLA 1 and CD105 but excretion of IL-6 into medium increased significantly. Remodeling of cytoskeleton started after first 4 h and was similar to preapoptotic changes. This data suggested the modification in cell adhesion and possible commitment of hMSC. It was observed that expression of alkaline phosphatase by MSC in osteogenic medium was more intensive in control. On the contrary, clinorotation did not change formation of mESC colonies and increased proliferation activity in LIF+-medium. However, the number of embryonic bodies after clinorotation was less than in static control. It is suggested that ESCs kept the viability and proliferative potential but decreased the differentiation ability after changes in gravity stimulation.

  19. Influence of culture and language sensitive physics on science attitude enhancement

    Science.gov (United States)

    Morales, Marie Paz E.

    2015-12-01

    The study critically explored how culture and language sensitive curriculum materials in physics improve Pangasinan learners' attitude towards science. Their cultural dimensions, epistemological beliefs, and views on integration of culture and language in the teaching and learning process determined their cultural preference or profile. Design and development of culture and language sensitive curriculum materials in physics were heavily influenced by these learners' cultural preference or profile. Pilot-study using interviews and focus group discussions with natives of Pangasinan and document analysis were conducted to identify the culture, practices, and traditions integrated in the lesson development. Comparison of experimental participants' pretest and posttest results on science attitude measure showed significant statistical difference. Appraisal of science attitude enhancement favored the experimental group over the control group. Qualitative data deduced from post implementation interviews, focus group discussions, and journal log entries showed the same trend in favor of the experimental participants. The study revealed that culture and language integration in the teaching and learning process of physics concepts enabled students to develop positive attitude to science, their culture, and native language.

  20. Cultural context and school counseling: Cultural sensitivity to advocate for social justice

    Directory of Open Access Journals (Sweden)

    Moshé Tatar

    2008-06-01

    Full Text Available In this paper the relevance of understanding the different meanings of culture in the counseling profession is presented. Two approaches to the concept of culture as they relate to counseling are suggested: the first approach stresses the organisational culture of the institution where the counselor works; the second —the multicultural approach— calls for the complex recognition of the variety of ethnic cultural backgrounds of those involved in the counseling situation. Professional practices are analysed as means for the reinforcement of present conditions or as ways for changing them. The concepts of empowerment of and advocacy for our clients are put forward as main components in the challenging new roles of the counseling profession. Implications for counselors are suggested.

  1. The Relationship Between Cultural Sensitivity and Assertiveness in Nursing Students from Turkey.

    Science.gov (United States)

    Kılıç, Serap Parlar; Sevinç, Sibel

    2017-07-01

    As foreigners live in and visit Turkey for various reasons, it is essential to provide culturally appropriate health care. This study was conducted to determine the relationship between cultural sensitivity and assertiveness in university nursing students. This descriptive, cross-sectional study was conducted at two universities in the cities of Kilis and Elazığ, Turkey. The study sample consisted of 444 nursing students. Data collection tools included a questionnaire about participant sociodemographic characteristics, Chen and Starosta's Intercultural Sensitivity Scale, and the Rathus Assertiveness Scale. The mean age of participants was 21.09 years. Most students (71.6%) were female and 34.7% of the students stayed at the hostel. Of the students, 44.4%, 27.5%, and 28.2% attended were the second-, third-, and fourth-year students, respectively. Participants were asked about problems related to caring for patients who speak different languages. The mean score for the Intercultural Sensitivity Scale was 89.42 ± 13.55 and the total score for all students for the Assertiveness Scale was 112.64 ± 15.61. We identified a positive relationship between total scores for the Intercultural Sensitivity Scale and the Assertiveness Scale ( p < .001). There was relationship between cultural sensitivity and gender and want to work overseas; assertiveness and year of nursing education and want to work overseas. Nursing students at both schools had a moderate level of cultural sensitivity and assertiveness. It has been determined that as assertiveness level of the students increased, intercultural sensitivity of them also increased. Consequently, it is concluded that training as assertive and self-confident individuals during the nursing education of students has a contribution to making patient-specific and culture-sensitive care.

  2. Evaluating the Linguistic Appropriateness and Cultural Sensitivity of a Self-Report System for Spanish-Speaking Patients with Cancer

    Directory of Open Access Journals (Sweden)

    Cindy Tofthagen

    2014-01-01

    Full Text Available Spanish speakers in the United States encounter numerous communication barriers during cancer treatment. Communication-focused interventions may help Spanish speakers communicate better with healthcare providers and manage symptoms and quality of life issues (SQOL. For this study, we developed a Spanish version of the electronic self-report assessment for cancer (ESRA-C, a web-based program that helps people with cancer report, track, and manage cancer-related SQOL. Four methods were used to evaluate the Spanish version. Focus groups and cognitive interviews were conducted with 51 Spanish-speaking individuals to elicit feedback. Readability was assessed using the Fry readability formula. The cultural sensitivity assessment tool was applied by three bilingual, bicultural reviewers. Revisions were made to personalize the introduction using a patient story and photos and to simplify language. Focus group participants endorsed changes to the program in a second round of focus groups. Cultural sensitivity of the program was scored unacceptable (x¯=3.0 for audiovisual material and acceptable (x¯=3.0 for written material. Fry reading levels ranged from 4th to 10th grade. Findings from this study provide several next steps to refine ESRA-C for Spanish speakers with cancer.

  3. Isolated hippocampal neurons in cryopreserved long-term cultures: development of neuroarchitecture and sensitivity to NMDA.

    Science.gov (United States)

    Mattson, M P; Kater, S B

    1988-01-01

    Isolated neurons in long-term culture provide a unique opportunity to address important problems in neuronal development. In the present study we established conditions for cryopreservation and long-term primary culture of isolated embryonic hippocampal neurons. This culture system was then used for initial characterizations of the development of neuroarchitecture and neurotransmitter response systems. Cryoprotection with 8% dimethylsulfoxide, slow freezing, and rapid thawing provided high-yield cultures which appeared normal in terms of cell types, mitotic ability, axonal and dendritic outgrowth, and sensitivity to glutamate neurotoxicity. A reduced medium volume and moderate elevation in extracellular K+ to 20 mM promoted survival of isolated neurons through 3 weeks of culture. The outgrowth of axons and dendrites in pyramidal-like neurons was found to differ over a 3-week culture period such that axons continued to grow at a relatively constant rate while dendritic outgrowth slowed during the second week and ceased by the end of week 3. Developmental changes were also observed in the sensitivity of pyramidal neurons to glutamate neurotoxicity; functional kainate/quisqualate receptors were present during the first week of culture, while responses to N-methyl-D-aspartic acid (NMDA) did not appear until the second week. The technologies for cryopreservation and long-term culture of isolated hippocampal neurons reported here provide a useful system in which to address a variety of problems in development neuroscience.

  4. Assessing culturally sensitive factors in the learning environment of science classrooms

    Science.gov (United States)

    Fisher, Darrell L.; Waldrip, Bruce G.

    1997-03-01

    As schools are becoming increasingly diverse in their scope and clientele, any examination of the interaction of culturally sensitive factors of students' learning environments with learning science assumes critical importance. The purpose of this exploratory study was to develop an instrument to assess learning environment factors that are culturally sensitive, to provide initial validation information on the instrument and to examine associations between students' perceptions of their learning environments and their attitudes towards science and achievement of enquiry skills. A measure of these factors of science student's learning environment, namely the Cultural Learning Environment Questionnaire (CLEQ), was developed from past learning environment instruments and influenced by Hofstede's four dimensions of culture (Power Distance, Uncertainty Avoidance, Individualism, and Masculinity/Femininity). The reliability and discriminant validity for each scale were obtained and associations between learning environment, attitude to science and enquiry skills achievement were found.

  5. [Culture-Sensitive Aspects in Diagnostics of Mental Distress in Refugees - Two Commented Case Reports].

    Science.gov (United States)

    Nesterko, Yuriy; Kaiser, Marie; Glaesmer, Heide

    2017-04-01

    High levels of mental disorders, especially PTSD, are commonly known among groups of people forced to leave their homeland as a consequence of war-related experiences (e. g. armed conflict, torture or persecution). Depending on the cultural background the perceptions of illnesses vary, different symptom presentation and thereupon different coping strategies respectively expectations towards health care services exist. To minimize the danger of misdiagnosis by different experts working with refugees in the host countries, a culture-sensitive diagnostic approach is needed from the beginning. This article describes important aspects of culture-sensitive diagnostics by means of 2 commented case reports. Special focus is set on the aspect of linguistic and in a broader sense cultural comprehension between therapist, client and if necessary language mediator. © Georg Thieme Verlag KG Stuttgart · New York.

  6. [On the Way to Culture-Sensitive Patient Information Materials: Results of a Focus Group Study].

    Science.gov (United States)

    Ries, Zivile; Frank, Fabian; Bermejo, Isaac; Kalaitsidou, Chariklia; Zill, Jördis; Dirmaier, Jörg; Härter, Martin; Bengel, Jürgen; Hölzel, Lars

    2017-09-28

    Aim This study was part of a double-blind randomised controlled trial aimed to evaluate the effects of culture-sensitive patient information materials (PIM) compared with standard translated material. The study aimed to obtain the data for the development of culture sensitive PIM about unipolar depression for the 4 largest migrant groups in Germany (Turkish, Polish, Russian and Italian migration background). Method A qualitative study using 4 manual-based focus groups (FG), one for each migrant group, with 29 participants (9 with a Turkish (TüG), 8 with a Polish (PoG), 5 with a Russian (RuG) and 7 with an Italian (ItG) migration background) was conducted. The discussions were recorded, transcribed and analyzed using qualitative content analysis. Results 7 categories were identified. For the (1.) development of a good culture-sensitive PIM an easy language, a clear structure, an assessable extent of information and the avoidance of stereotypes were highlighted cross-culturally in all four FG. RuG and PoG had the largest (2.) lack of information about the German health care system. Concerning the (3.) illness perception RuG named problems with recognizing and understanding depression. PoG, RuG and TüG thematized (4.) feared consequences of the illness and of professional helpseeking. ItG, PoG, RuG had fears concerning (5.) psychotropic drugs as a result from insufficient knowledge about medication. For (6.) doctor-patient relationship cultural specifics were identified in RuG and TüG and for (7.) migration or culture specific reasons for depression in RuG, ItG and TüG. Conclusion Although the identified categories were relevant for all or for the majority of migrant groups, for most categories specific cultural aspects were discovered. These findings show the importance of a culture sensitive adaptation of PIM. © Georg Thieme Verlag KG Stuttgart · New York.

  7. Temperament trait of sensory processing sensitivity moderates cultural differences in neural response

    OpenAIRE

    Aron, Arthur; Ketay, Sarah; Hedden, Trey; Aron, Elaine N; Rose Markus, Hazel; John D E Gabrieli

    2010-01-01

    This study focused on a possible temperament-by-culture interaction. Specifically, it explored whether a basic temperament/personality trait (sensory processing sensitivity; SPS), perhaps having a genetic component, might moderate a previously established cultural difference in neural responses when making context-dependent vs context-independent judgments of simple visual stimuli. SPS has been hypothesized to underlie what has been called inhibitedness or reactivity in infants, introversion ...

  8. A Culturally Sensitive Analysis of Culture in the Context of Context: When Is Enough Enough?

    Science.gov (United States)

    Kahn, Peter H., Jr.

    Cultural context is not the sole source of human knowledge. Postmodern theory, in both its deconstructionist and affirmative approaches, offers an incomplete basis by which to study race, class, and gender, and undermines ethical interaction. Deconstructionism calls for the abandonment of generalizable research findings, asserting that the concept…

  9. Sensitivity Analysis of Linear Programming and Quadratic Programming Algorithms for Control Allocation

    Science.gov (United States)

    Frost, Susan A.; Bodson, Marc; Acosta, Diana M.

    2009-01-01

    The Next Generation (NextGen) transport aircraft configurations being investigated as part of the NASA Aeronautics Subsonic Fixed Wing Project have more control surfaces, or control effectors, than existing transport aircraft configurations. Conventional flight control is achieved through two symmetric elevators, two antisymmetric ailerons, and a rudder. The five effectors, reduced to three command variables, produce moments along the three main axes of the aircraft and enable the pilot to control the attitude and flight path of the aircraft. The NextGen aircraft will have additional redundant control effectors to control the three moments, creating a situation where the aircraft is over-actuated and where a simple relationship does not exist anymore between the required effector deflections and the desired moments. NextGen flight controllers will incorporate control allocation algorithms to determine the optimal effector commands and attain the desired moments, taking into account the effector limits. Approaches to solving the problem using linear programming and quadratic programming algorithms have been proposed and tested. It is of great interest to understand their relative advantages and disadvantages and how design parameters may affect their properties. In this paper, we investigate the sensitivity of the effector commands with respect to the desired moments and show on some examples that the solutions provided using the l2 norm of quadratic programming are less sensitive than those using the l1 norm of linear programming.

  10. Practical strategies for providing culturally sensitive, ethical care in developing nations.

    Science.gov (United States)

    Crigger, Nancy J; Holcomb, Lygia

    2007-01-01

    Providing health care in developing nations results in cultural and ethical challenges for health care professionals. The authors' intent is to raise readers' awareness of how to maintain an ethical and culturally sensitive approach to practice in developing nations. Four practical approaches to ethical decision-making, developed from the literature and praxis, in conjunction with traditional moral theory and guidelines from professional and international organizations are discussed. Ethical multiculturalism, a view that combines universalism and multiculturalism undergirds culturally appropriate and ethically responsive decisions.

  11. Preimplantation embryo programming: transcription, epigenetics, and culture environment.

    Science.gov (United States)

    Duranthon, Veronique; Watson, Andrew J; Lonergan, Patrick

    2008-02-01

    Preimplantation development directs the formation of an implantation- or attachment-competent embryo so that metabolic interactions with the uterus can occur, pregnancy can be initiated, and fetal development can be sustained. The preimplantation embryo exhibits a form of autonomous development fueled by products provided by the oocyte and also from activation of the embryo's genome. Despite this autonomy, the preimplantation embryo is highly influenced by factors in the external environment and in extreme situations, such as those presented by embryo culture or nuclear transfer, the ability of the embryo to adapt to the changing environmental conditions or chromatin to become reprogrammed can exceed its own adaptive capacity, resulting in aberrant embryonic development. Nuclear transfer or embryo culture-induced influences not only affect implantation and establishment of pregnancy but also can extend to fetal and postnatal development and affect susceptibility to disease in later life. It is therefore critical to define the basic program controlling preimplantation development, and also to utilize nuclear transfer and embryo culture models so that we may design healthier environments for preimplantation embryos to thrive in and also minimize the potential for negative consequences during pregnancy and post-gestational life. In addition, it is necessary to couple gene expression analysis with the investigation of gene function so that effects on gene expression can be fully understood. The purpose of this short review is to highlight our knowledge of the mechanisms controlling preimplantation development and report how those mechanisms may be influenced by nuclear transfer and embryo culture.

  12. Computer Programming Games and Gender Oriented Cultural Forms

    Science.gov (United States)

    AlSulaiman, Sarah Abdulmalik

    I present the design and evaluation of two games designed to help elementary and middle school students learn computer programming concepts. The first game was designed to be "gender neutral", aligning with might be described as a consensus opinion on best practices for computational learning environments. The second game, based on the cultural form of dress up dolls was deliberately designed to appeal to females. I recruited 70 participants in an international two-phase study to investigate the relationship between games, gender, attitudes towards computer programming, and learning. My findings suggest that while the two games were equally effective in terms of learning outcomes, I saw differences in motivation between players of the two games. Specifically, participants who reported a preference for female- oriented games were more motivated to learn about computer programming when they played a game that they perceived as designed for females. In addition, I describe how the two games seemed to encourage different types of social activity between players in a classroom setting. Based on these results, I reflect on the strategy of exclusively designing games and activities as "gender neutral", and suggest that employing cultural forms, including gendered ones, may help create a more productive experience for learners.

  13. CALIBRATION, OPTIMIZATION, AND SENSITIVITY AND UNCERTAINTY ALGORITHMS APPLICATION PROGRAMMING INTERFACE (COSU-API)

    Science.gov (United States)

    The Application Programming Interface (API) for Uncertainty Analysis, Sensitivity Analysis, and Parameter Estimation (UA/SA/PE API) tool development, here fore referred to as the Calibration, Optimization, and Sensitivity and Uncertainty Algorithms API (COSU-API), was initially d...

  14. Adapting the SRQ for Ethiopian Populations : A Culturally-Sensitive Psychiatric Screening Instrument

    NARCIS (Netherlands)

    Youngmann, Rafael; Zilber, Nelly; Workneh, Fikre; Giel, Robert

    2008-01-01

    The objective of the study was to develop a culturally sensitive psychiatric screening instrument valid for Ethiopians in Ethiopia and Israel. The study sample was composed of 356 Amharic-speaking Ethiopians from Ethiopia and Israel, aged 18-55, divided into three groups: i) general population; ii)

  15. How Commercial and "Violent" Video Games Can Promote Culturally Sensitive Science Learning: Some Questions and Challenges

    Science.gov (United States)

    Kwah, Helen

    2012-01-01

    In their paper, Munoz and El-Hani propose to bring video games into science classrooms to promote culturally sensitive ethics and citizenship education. Instead of bringing "educational" games, Munoz and El-Hani take a more creative route and include games such as Fallout 3[R] precisely because they are popular and they reproduce ideological and…

  16. Sensitivity, specificity and predictive value of blood cultures from cattle clinically suspected of bacterial endocarditis

    DEFF Research Database (Denmark)

    Houe, Hans; Eriksen, L.; Jungersen, Gregers;

    1993-01-01

    This study investigated the number of blood culture-positive cattle among 215 animals clinically suspected of having bacterial endocarditis. For animals that were necropsied, the sensitivity, specificity and predictive value of the diagnosis of endocarditis were calculated on the basis...

  17. Developing Culturally Sensitive HIV/AIDS and Substance Abuse Prevention Curricula for Native American Youth.

    Science.gov (United States)

    Baldwin, Julie A.; And Others

    1996-01-01

    Critical steps in developing these curricula included: selecting integrative theory to address multidimensional antecedents of HIV/AIDS and substance abuse among Native Americans; using ethnography to obtain input from target groups and community members to ensure developmental and cultural sensitivity; and using process and outcome evaluations of…

  18. Listening to the third voices of Pangasinan students: designing and enacting culturally sensitive curriculum

    Science.gov (United States)

    Wilder, Phillip

    2015-12-01

    This response builds upon Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" by exploring how an expanded understanding of the ubiquitous nature of adolescent literacy practices and identities challenge traditional notions of "in school" and "out of school" cultural spaces. Listening to the "third voices" of adolescents can promote a deeper understanding of the complex literate lives of Pangasinan students and inform both the official and the enacted culturally sensitive curriculum. To hear the literate lives of adolescents is to push back against politically dehumanizing and "de-literacizing" neo-liberal educational policies and practices which privilege a singular, whitewashed view of literacy in order to standardize curriculum and instruction, preserve power in the hands of the powerful, and exacerbate socio-economic, racial, ethnic, and linguistic divisions.

  19. Group cognitive-behavioral therapy for depression in Spanish: culture-sensitive manualized treatment in practice.

    Science.gov (United States)

    Aguilera, Adrian; Garza, Monica J; Muñoz, Ricardo F

    2010-08-01

    The authors applied cognitive-behavioral therapy (CBT) for depression using the Healthy Management of Reality treatment manual. This 16-week group treatment comprised four 4-week modules: thoughts (cognitive restructuring), activities (behavioral activation), people (interpersonal skills training), and health (addresses physical health and depression). They illustrated the use of the culture-sensitive treatment manuals by way of the member characteristics and clinical process of a Spanish-language CBT group for depression. They highlighted the challenges and satisfactions of working with a Spanish-speaking population in the public sector, and focused on how culture and socioeconomic status influence patients, and how to adapt treatment to these factors. Last, they demonstrated how technological advances integrate with culture-sensitive, evidence-based treatments to better serve this population and reduce disparities.

  20. PRIMARY TEACHERS’ PERCEPTION OF CULTURAL DİVERSITY AND INTERCULTURAL SENSITIVITY

    Directory of Open Access Journals (Sweden)

    Öznur Rengi

    2014-12-01

    Full Text Available The teachers’ perception of cultural diversity is important to provide justice and equality in education, prevent the cultural conflicts and communication productivity of interactions in schools that there are cultural differences. This study aims to determine primary teachers’ perception of cultural diversity and observe teachers’ levels of “intercultural sensitivity” in relation to their students. The working group in this research is 286 primary teachers who work public schools province of Kocaeli (Çayırova in 2013-2014 acedemic year. The mixed model is used. The research data was collected by using the “İntercultural Sensitivity Scale” (Chen and Starosta, 2000. It is used t-tests, test of ANOVA and arithmetic average for composing quantitative data. The qualitative data was collected by using the teachers’ answers that “ What do you think the cultural differences of students?”. It is provided content analysis for qualitative data. It is seen that the teachers’ intercultural sensitivity is high. Morever ‘‘differences of languages’’ are the most striking the perception of primary teachers’ cultural differences.

  1. The Relationship of Workplace Culture With Nursing-Sensitive Organizational Factors.

    Science.gov (United States)

    Hahtela, Nina; McCormack, Brendan; Paavilainen, Eija; Slater, Paul; Helminen, Mika; Suominen, Tarja

    2015-01-01

    The aim of this study is to explore the relations of workplace culture on nursing-sensitive organizational factors. The need for standardized and valid measures for nursing-sensitive organizational outcomes has already been recognized in the literature. A cross-sectional questionnaire survey of 21 inpatient acute care units in 9 organizations at the municipal primary healthcare level was conducted. Participants included licensed practical nurses, registered nurses, and nurse managers. Workplace culture, especially the overarching factor of stress, correlated with the use of supplemental nursing staff and patients' length of stay. It is essential to find and test workplace-sensitive indicators so that managers will have a wider range of methods to plan and evaluate nursing outcomes.

  2. Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan

    Science.gov (United States)

    Patrick, Alison; Seluanov, Michael; Hwang, Chaewon; Tam, Jonathan; Khan, Tanya; Morgenstern, Ari; Wiener, Lauren; Vazquez, Juan M.; Zafar, Hiba; Wen, Robert; Muratkalyeva, Malika; Doerig, Katherine; Zagorulya, Maria; Cole, Lauren; Catalano, Sophia; Lobo Ladd, Aliny AB; Coppi, A. Augusto; Coşkun, Yüksel; Tian, Xiao; Ablaeva, Julia; Nevo, Eviatar; Gladyshev, Vadim N.; Zhang, Zhengdong D.; Vijg, Jan; Seluanov, Andrei; Gorbunova, Vera

    2016-01-01

    Differences in the way human and mouse fibroblasts experience senescence in culture had long puzzled researchers. While senescence of human cells is mediated by telomere shortening, Parrinello et al. demonstrated that senescence of mouse cells is caused by extreme oxygen sensitivity. It was hypothesized that the striking difference in oxygen sensitivity between mouse and human cells explains their different rates of aging. To test if this hypothesis is broadly applicable, we cultured cells from 16 rodent species with diverse lifespans in 3% and 21% oxygen and compared their growth rates. Unexpectedly, fibroblasts derived from laboratory mouse strains were the only cells demonstrating extreme sensitivity to oxygen. Cells from hamster, muskrat, woodchuck, capybara, blind mole rat, paca, squirrel, beaver, naked mole rat and wild-caught mice were mildly sensitive to oxygen, while cells from rat, gerbil, deer mouse, chipmunk, guinea pig and chinchilla showed no difference in the growth rate between 3% and 21% oxygen. We conclude that, although the growth of primary fibroblasts is generally improved by maintaining cells in 3% oxygen, the extreme oxygen sensitivity is a peculiarity of laboratory mouse strains, possibly related to their very long telomeres, and fibroblast oxygen sensitivity does not directly correlate with species' lifespan. PMID:27163160

  3. The Nuer Nutrition Education Program: breaking down cultural barriers.

    Science.gov (United States)

    Laverentz, M L; Cox, C C; Jordan, M

    1999-01-01

    Very little is known about the Nuer culture, partly because of its widely misunderstood language and because of the mixture of its people with the other tribes in Africa, according to Evans-Pritchard). However, it is known that the Nuer women's roles in the family seem to be centered around cooking duties. In the Nuer culture, no work is considered degrading, and the women know and accept their domestic duties. During the summer of 1996, a pilot project was conducted as an attempt to help Nuer refugee women of Des Moines, Iowa, incorporate nutritional concepts and American food preparation techniques into their existing methods of food preparation. The barriers faced involved the Nuer women's unfamiliarity with American foods and household items and their inability to read and understand English. Cultural issues and barriers were overcome when the health educator was willing to take the time to gain the trust and respect of the Nuer people. Structured interviews indicated an increase in knowledge of American foods and cooking skills. This education program in no way meant to replace traditional Nuer cooking methods; rather, it acted as a way to adjust to life in the United States.

  4. Highly Sensitive Bacteriophage-Based Detection of Brucella abortus in Mixed Culture and Spiked Blood

    Directory of Open Access Journals (Sweden)

    Kirill V. Sergueev

    2017-06-01

    Full Text Available For decades, bacteriophages (phages have been used for Brucella species identification in the diagnosis and epidemiology of brucellosis. Traditional Brucella phage typing is a multi-day procedure including the isolation of a pure culture, a step that can take up to three weeks. In this study, we focused on the use of brucellaphages for sensitive detection of the pathogen in clinical and other complex samples, and developed an indirect method of Brucella detection using real-time quantitative PCR monitoring of brucellaphage DNA amplification via replication on live Brucella cells. This assay allowed the detection of single bacteria (down to 1 colony-forming unit per milliliter within 72 h without DNA extraction and purification steps. The technique was equally efficient with Brucella abortus pure culture and with mixed cultures of B. abortus and α-proteobacterial near neighbors that can be misidentified as Brucella spp., Ochrobactrum anthropi and Afipia felis. The addition of a simple short sample preparation step enabled the indirect phage-based detection of B. abortus in spiked blood, with the same high sensitivity. This indirect phage-based detection assay enables the rapid and sensitive detection of live B. abortus in mixed cultures and in blood samples, and can potentially be applied for detection in other clinical samples and other complex sample types.

  5. Increased sensitivity to ET-1 in rat cerebral arteries following organ culture

    DEFF Research Database (Denmark)

    Hansen-Schwartz, J; Edvinsson, L

    2000-01-01

    Endothelin-1 (ET-1) is recognized as being involved in the pathophysiology of cerebrovascular diseases. Using organ culture as a model for possible pathological changes we studied changes in ET(A) and ETB receptor function using a sensitive in vitro method. We observed an up-regulation of the ET......(B) receptor and an amazingly increased sensitivity to ET-1 by 3 log units in pEC50; pEC50(fresh) was 8.7 +/- 0.1, and pEC50(cultured) was 11.7 +/- 0.3. pA2 for FR139317 in the fresh vessel was 7.0 +/- 0.2 whereas it could not be obtained for the cultured vessel, indicating a possible cross-talk between the ET......(A) and ET(B) receptors. The increased sensitivity to ET-1 could also take place during cerebrovascular disease such as stroke or haemorrhage rendering the vessels considerably more sensitive to ET-1....

  6. An investigation of Helicobacter pylori using culture, histopathological and serological examination methods and its antimicrobial sensitivities.

    Science.gov (United States)

    Inan, Asuman; Gulsun, Serda; Guveli, Hakan; Tascioglu, Jale; Goktas, Pasa

    2005-04-01

    In this study, the determination of Helicobacter pylori (H. pylori) by culture, histopathological and serological methods in cases of endoscopically diagnosed as duodenitis and duodenal ulcer (DU), a comparison of their relative advantages, and its antibiotic sensitivities were investigated. Helicobacter pylori was investigated using 3 methods (culture, histopathological and serological examination) in 50 patients (25 diagnosed with duodenitis and 25 with DU) at the Department of Gastroenterohepatology, Istanbul Haydarpasa Numune Hospital, Turkey between December 2000 and February 2001. An investigation into its antibiotic sensitivities to amoxicillin, clarithromycin, metronidazole and azithromycin by disc diffusion methods and to amoxicillin and clarithromycin by E-test were investigated. Helicobacter pylori bacteria were observed in Gram stained preparates prepared from biopsy material in 34 out of 50 patients (68%), and were able to be produced in active culture in all these cases. Histopathological examination revealed the presence of H. pylori in 80% cases of DU and 60% cases of duodenitis; anti-CagA(IgG) was positively determined in 88% DU cases and in 60% duodenitis cases. There was a significant difference between the 2 groups in terms of diagnosis by histopathological and serological methods. The difference between the 2 groups produced in active culture in 84% cases of DU cases and 52% of duodenitis was statistically significant (p=0.0322). Using the E-test and disc diffusion methods, 8.8% of the strains that reproduced in culture were resistant to and 91.2% were sensitive to clarithromycin. All strains were determined to be sensitive to amoxicillin: 17.6% of the strains were determined to be resistant to metronidazole, 11.7% to azithromycin. It was observed that Gram staining is a rapid and reliable method of pre-diagnosis for H. pylori; that histopathological examination methods are of considerable importance in diagnosis; and that the investigation of

  7. Development and Validation of the Cultural Competence of Program Evaluators (CCPE) Self-Report Scale

    Science.gov (United States)

    Dunaway, Krystall E.; Morrow, Jennifer A.; Porter, Bryan E.

    2012-01-01

    No self-report measure of cultural competence currently exists in program evaluation. Adapting items from cultural competence measures in fields such as counseling and nursing, the researchers developed the Cultural Competence of Program Evaluators (CCPE) self-report scale. The goals of this study were to validate the CCPE and to assess…

  8. Bioimpedance monitoring of 3D cell culturing--complementary electrode configurations for enhanced spatial sensitivity.

    Science.gov (United States)

    Canali, Chiara; Heiskanen, Arto; Muhammad, Haseena Bashir; Høyum, Per; Pettersen, Fred-Johan; Hemmingsen, Mette; Wolff, Anders; Dufva, Martin; Martinsen, Ørjan Grøttem; Emnéus, Jenny

    2015-01-15

    A bioimpedance platform is presented as a promising tool for non-invasive real-time monitoring of the entire process of three-dimensional (3D) cell culturing in a hydrogel scaffold. In this study, the dynamics involved in the whole process of 3D cell culturing, starting from polymerisation of a bare 3D gelatin scaffold, to human mesenchymal stem cell (MSC) encapsulation and proliferation, was monitored over time. The platform consists of a large rectangular culture chamber with four embedded vertical gold plate electrodes that were exploited in two- and three terminal (2T and 3T) measurement configurations. By switching between the different combinations of electrode couples, it was possible to generate a multiplexing-like approach, which allowed for collecting spatially distributed information within the 3D space. Computational finite element (FE) analysis and electrochemical impedance spectroscopic (EIS) characterisation were used to determine the configurations' sensitivity field localisation. The 2T setup gives insight into the interfacial phenomena at both electrode surfaces and covers the central part of the 3D cell culture volume, while the four 3T modes provide focus on the dynamics at the corners of the 3D culture chamber. By combining a number of electrode configurations, complementary spatially distributed information on a large 3D cell culture can be obtained with maximised sensitivity in the entire 3D space. The experimental results show that cell proliferation can be monitored within the tested biomimetic environment, paving the way to further developments in bioimpedance tracking of 3D cell cultures and tissue engineering.

  9. DIAGNOSIS OF CULTURE POSITIVE URINARY TRACT INFECTIONS AND THEIR ANTIMICROBIAL SENSITIVITY PROFILE IN TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Prince Sreekumar Pius

    2016-12-01

    Full Text Available BACKGROUND Urinary tract infection is very common all over the world and in India more than 10 million cases are reported per year. It is one of the common infections diagnosed in the outpatients as well as the hospitalised patients. Empirical treatment of community acquired urinary tract infections are determined by the antibiotic sensitivity in a population. This study was conducted to determine the antimicrobial sensitivity amongst the uropathogens to help establish local guidelines on treatment of urinary tract infection. MATERIALS AND METHODS In this study, we collected 1306 samples from patients in whom we suspected to have urinary tract infection based on clinical signs and symptoms (e.g. with fever (greater than 38°C without another explanation or from a patient who had at least one urinary symptom (dysuria, urgency, frequency, or suprapubic pain or tenderness in our hospital during January 2016-June 2016. RESULTS Urine cultures were positive for 18% of the patients. Among these cultures, Klebsiella pneumonia (41%, Escherichia coli (35% and Pseudomonas aeruginosa (7% were the common organisms found. Highest antimicrobial sensitivity amongst these pathogens was found with cefoperazone/sulbactam and amikacin. CONCLUSION Cefoperazone/sulbactam and amikacin were the highly sensitive systemic antibiotics while ciprofloxacin and norfloxacin were the sensitive oral antibiotics in our locality.

  10. Environmentally Sensitive Areas Surveys Program threatened and endangered species survey: Progress report. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    King, A.L.; Awl, D.J.; Gabrielsen, C.A.

    1994-09-01

    The Endangered Species Act (originally passed in 1973) is a Federal statute that protects both animal and plant species. The Endangered Species Act identifies species which are, without careful management, in danger of becoming extinct and species that are considered threatened. Along with the designation of threatened or endangered, the Endangered Species Act provides for the identification of appropriate habitat for these species. Since 1993, the United States Department of Energy`s (DOE) Environmental Restoration (ER) Program has supported a program to survey the Oak Ridge Reservation (ORR) for threatened and endangered species. The Environmentally Sensitive Areas Surveys Program initiated vascular plant surveys during fiscal year 1993 and vertebrate animal surveys during fiscal year 1994 to determine the baseline condition of threatened and endangered species on the ORR at the present time. Data collected during these surveys are currently aiding Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Remedial Investigations on the ORR. They also provide data for ER and Waste Management decision documents, ensure that decisions have technical and legal defensibility, provide a baseline for ensuring compliance with principal legal requirements and will increase public confidence in DOE`s adherence to all related environmental resources rules, laws, regulations, and instructions. This report discusses the progress to date of the threatened and endangered species surveys of the ORR.

  11. Analytic central path, sensitivity analysis and parametric linear programming

    NARCIS (Netherlands)

    A.G. Holder; J.F. Sturm; S. Zhang (Shuzhong)

    1998-01-01

    textabstractIn this paper we consider properties of the central path and the analytic center of the optimal face in the context of parametric linear programming. We first show that if the right-hand side vector of a standard linear program is perturbed, then the analytic center of the optimal face

  12. The Role of Confucian Cultural Values and Politics in Planning Educational Programs for Adults in Korea

    Science.gov (United States)

    Ryu, Kiung; Cervero, Ronald M.

    2011-01-01

    Program planning activities are not culturally neutral but are replete with various cultural values and affected by them. This qualitative study was conducted in Korea and examines how cultural values influence educational planning in Korea. Specifically, the study was to examine how Confucian cultural values play out in educational planning in…

  13. Perceived Cultural Responsiveness and Effectiveness of a Speech and Language Program for Indigenous Preschool Students

    Science.gov (United States)

    McIntosh, Kent; Craft, Calli B.; MacKay, Leslie D.

    2013-01-01

    Despite an increasing need for culturally relevant curricula, what is considered culturally responsive and how it is assessed is under-researched. The present study examined the perceived cultural responsiveness and effectiveness of an early intervention program designed to teach early language skills and expose students to Indigenous culture, the…

  14. Sensitivity of PCR IS6110 in relation to culture and staining in Pott′s disease

    Directory of Open Access Journals (Sweden)

    Manoj Kumar

    2013-01-01

    Full Text Available Background: Rapid diagnosis is essential to decrease the morbidity and mortality of Pott′s disease. The bacteriological methods are time-consuming or insensitive. Polymerase chain reaction (PCR provides a rapid diagnostic tool and hope for early diagnosis of this disease. The aim of this study was to compare and assess of a rapid and effective method among diagnostic battery (Ziehl-Neelsen (ZN microscopy, BACTEC culture and PCR of Pott′s disease. Materials and Methods: Sixty-five specimens from clinico-radiological suspected cases of Pott′s disease were included in this study. They were processed for ZN microscopy, BACTEC culture, and PCR IS6110. The tests tool′s efficiency, positive agreement Kc (Kappa coefficient, and significance level (P value were calculated for correlation between PCR and performed tests. Results: The PCR sensitivity reached to 96% and 46.3% among positive and negative specimens on ZN microscopy. Further, 94% and 36.4% sensitivity were found among positive and negative specimens by BACTEC culture. The total 38 (58.5% specimens were detected either ZN microscopy or by BACTEC culture. Thus, the overall sensitivity and specificity of PCR were 95% and 74.1%. The kappa coefficient and P value, calculated for PCR against BACTEC culture and combined results of performed bacteriological tests were (Kc=0.60, (P<0.001 and (Kc=0.70, (P<0.001, respectively. Above statistical relations showed a fair agreement with significant differences. Conclusion: The PCR IS6110 may be useful in rapid detection of clinico-radiological suspected cases of Pott′s disease and those that are negative with bacteriological methods.

  15. [The sensitivity to antibiotics of biofilm cultures of toxigenic strains Corynebacterium diphtheriae].

    Science.gov (United States)

    Frolova, Ya N; Kharseyeva, G G; Mironov, A Yu

    2014-06-01

    The article presents analysis of sensitivity to antibacterial preparations of typical and biofilm culture of museum strain of Corynebacterium diphtheriae gravis tox+ SV-665. The strain was obtained from the L.A. Tarasevitch state research institute of standardization and control of medical biological preparations. The second strain C. diphtheriaecirculates gravis tox+ circulates in population of the Rostov oblast and it was recovered from patient with diagnosis of "localized form of diphtheria" by bacteriologic laboratory "1002 CGSEN SKVO" of Rostov-on-Don. The week and month biofilm cultures of both strains of C. diphtheriae gravis tox+ were used. The sensitivity to antibacterial preparations of typical and biofilm cultures of museum and circulating in population strains of agent of diphtheria were detected using minimal suppressing concentration by technique of serial dilutions in fluid growth medium. It is demonstrated that the most effective in respect of C. diphtheriae are such preparations as cefotaxinum, gentamycinum, lincomycin, canamycin and cefasolin. The sensitivity of pathogen in composition of biofilm to these preparations has no changes.

  16. Improving Medical Decision Making and Health Promotion through Culture-Sensitive Health Communication: An Agenda for Science and Practice.

    Science.gov (United States)

    Betsch, Cornelia; Böhm, Robert; Airhihenbuwa, Collins O; Butler, Robb; Chapman, Gretchen B; Haase, Niels; Herrmann, Benedikt; Igarashi, Tasuku; Kitayama, Shinobu; Korn, Lars; Nurm, Ülla-Karin; Rohrmann, Bernd; Rothman, Alexander J; Shavitt, Sharon; Updegraff, John A; Uskul, Ayse K

    2016-10-01

    This review introduces the concept of culture-sensitive health communication. The basic premise is that congruency between the recipient's cultural characteristics and the respective message will increase the communication's effectiveness. Culture-sensitive health communication is therefore defined as the deliberate and evidence-informed adaptation of health communication to the recipients' cultural background in order to increase knowledge and improve preparation for medical decision making and to enhance the persuasiveness of messages in health promotion. To achieve effective health communication in varying cultural contexts, an empirically and theoretically based understanding of culture will be indispensable. We therefore define culture, discuss which evolutionary and structural factors contribute to the development of cultural diversity, and examine how differences are conceptualized as scientific constructs in current models of cultural differences. In addition, we will explicate the implications of cultural differences for psychological theorizing, because common constructs of health behavior theories and decision making, such as attitudes or risk perception, are subject to cultural variation. In terms of communication, we will review both communication strategies and channels that are used to disseminate health messages, and we will discuss the implications of cultural differences for their effectiveness. Finally, we propose an agenda both for science and for practice to advance and apply the evidence base for culture-sensitive health communication. This calls for more interdisciplinary research between science and practice but also between scientific disciplines and between basic and applied research. © The Author(s) 2015.

  17. Sensitive Situations. The DLM Early Childhood Program Professional Library.

    Science.gov (United States)

    Schiller, Pam

    Teachers know how to educate young children, but many feel ill-prepared when faced with students' emotional issues in the classroom. This book is intended as a resource for early childhood teachers who find themselves in the middle of such "sensitive situations." The information is presented by using a fictional, but typical, scenario…

  18. Sensitive Situations. The DLM Early Childhood Program Professional Library.

    Science.gov (United States)

    Schiller, Pam

    Teachers know how to educate young children, but many feel ill-prepared when faced with students' emotional issues in the classroom. This book is intended as a resource for early childhood teachers who find themselves in the middle of such "sensitive situations." The information is presented by using a fictional, but typical, scenario…

  19. Temperament trait of sensory processing sensitivity moderates cultural differences in neural response.

    Science.gov (United States)

    Aron, Arthur; Ketay, Sarah; Hedden, Trey; Aron, Elaine N; Rose Markus, Hazel; Gabrieli, John D E

    2010-06-01

    This study focused on a possible temperament-by-culture interaction. Specifically, it explored whether a basic temperament/personality trait (sensory processing sensitivity; SPS), perhaps having a genetic component, might moderate a previously established cultural difference in neural responses when making context-dependent vs context-independent judgments of simple visual stimuli. SPS has been hypothesized to underlie what has been called inhibitedness or reactivity in infants, introversion in adults, and reactivity or responsivness in diverse animal species. Some biologists view the trait as one of two innate strategies-observing carefully before acting vs being first to act. Thus the central characteristic of SPS is hypothesized to be a deep processing of information. Here, 10 European-Americans and 10 East Asians underwent functional magnetic resonance imaging while performing simple visuospatial tasks emphasizing judgments that were either context independent (typically easier for Americans) or context dependent (typically easier for Asians). As reported elsewhere, each group exhibited greater activation for the culturally non-preferred task in frontal and parietal regions associated with greater effort in attention and working memory. However, further analyses, reported here for the first time, provided preliminary support for moderation by SPS. Consistent with the careful-processing theory, high-SPS individuals showed little cultural difference; low-SPS, strong culture differences.

  20. Implementing Family Literacy Programs for Linguistically and Culturally Diverse Populations: Key Elements to Consider

    National Research Council Canada - National Science Library

    Delia C Garcia; Deborah J Hasson

    2004-01-01

    .... These programs have been particularly beneficial for linguistically and culturally diverse families, since they provide opportunities for adult family members to acquire English language/literacy...

  1. Analytic central path, sensitivity analysis and parametric linear programming

    OpenAIRE

    A.G. Holder; Sturm, J.F.; Zhang, Shuzhong

    1998-01-01

    textabstractIn this paper we consider properties of the central path and the analytic center of the optimal face in the context of parametric linear programming. We first show that if the right-hand side vector of a standard linear program is perturbed, then the analytic center of the optimal face is one-side differentiable with respect to the perturbation parameter. In that case we also show that the whole analytic central path shifts in a uniform fashion. When the objective vector is pertur...

  2. Development of an Inventory for Health-Care Office Staff to Self-Assess Their Patient-Centered Cultural Sensitivity

    Directory of Open Access Journals (Sweden)

    Carolyn M. Tucker

    2016-02-01

    Full Text Available Background: Patient-centered culturally sensitive health care (PC-CSHC is a best practice approach for improving health-care delivery to culturally diverse populations and reducing health disparities. Despite patients’ report that cultural sensitivity by health-care office staff is an important aspect of PC-CSHC, the majority of available research on PC-CSHC focuses exclusively on health-care providers. This may be due in part to the paucity of instruments available to assess the cultural sensitivity of health-care office staff. The objective of the present study is to determine the psychometric properties of the Tucker-Culturally Sensitive Health Care Office Staff Inventory-Self-Assessment Form (T-CSHCOSI-SAF. This instrument is designed to enable health-care office staff to self-assess their level of agreement that they display behaviors and attitudes that culturally diverse patients have identified as office staff cultural sensitivity indicators. Methods: A sample of 510 health-care office staff were recruited at 67 health-care sites across the United States. These health-care office staff anonymously completed the T-CSHCOSI-SAF and a demographic data questionnaire. Results and Level of Evidence: Confirmatory factor analyses of the T-CSHCOSI-SAF revealed that this inventory has 2 factors with high internal consistency reliability (Cronbach’s αs= .916 and .912. Conclusion and Implications: The T-CSHCOSI-SAF is a useful inventory for health-care office staff to assess their own level of patient-centered cultural sensitivity. Such self-assessment data can be used in the development and implementation of trainings to promote patient-centered cultural sensitivity of health-care office staff and to help draw the attention of these staff to displaying patient-centered cultural sensitivity.

  3. Development of an Inventory for Health-Care Office Staff to Self-Assess Their Patient-Centered Cultural Sensitivity

    Directory of Open Access Journals (Sweden)

    Carolyn M. Tucker

    2016-02-01

    Full Text Available Background: Patient-centered culturally sensitive health care (PC-CSHC is a best practice approach for improving health-care delivery to culturally diverse populations and reducing health disparities. Despite patients’ report that cultural sensitivity by health-care office staff is an important aspect of PC-CSHC, the majority of available research on PC-CSHC focuses exclusively on health-care providers. This may be due in part to the paucity of instruments available to assess the cultural sensitivity of health-care office staff. The objective of the present study is to determine the psychometric properties of the Tucker-Culturally Sensitive Health Care Office Staff Inventory-Self-Assessment Form (T-CSHCOSI-SAF. This instrument is designed to enable health-care office staff to self-assess their level of agreement that they display behaviors and attitudes that culturally diverse patients have identified as office staff cultural sensitivity indicators. Methods: A sample of 510 health-care office staff were recruited at 67 health-care sites across the United States. These health-care office staff anonymously completed the T-CSHCOSI-SAF and a demographic data questionnaire. Results and Level of Evidence: Confirmatory factor analyses of the T-CSHCOSI-SAF revealed that this inventory has 2 factors with high internal consistency reliability (Cronbach’s αs= .916 and .912. Conclusion and Implications: The T-CSHCOSI-SAF is a useful inventory for health-care office staff to assess their own level of patient-centered cultural sensitivity. Such self-assessment data can be used in the development and implementation of trainings to promote patient-centered cultural sensitivity of health-care office staff and to help draw the attention of these staff to displaying patient-centered cultural sensitivity.

  4. Paratingent Derivative Applied to the Measure of the Sensitivity in Multiobjective Differential Programming

    Directory of Open Access Journals (Sweden)

    F. García

    2013-01-01

    Full Text Available We analyse the sensitivity of differential programs of the form subject to where and are maps whose respective images lie in ordered Banach spaces. Following previous works on multiobjective programming, the notion of -optimal solution is used. The behaviour of some nonsingleton sets of -optimal solutions according to changes of the parameter in the problem is analysed. The main result of the work states that the sensitivity of the program is measured by a Lagrange multiplier plus a projection of its derivative. This sensitivity is measured by means of the paratingent derivative.

  5. On Sensitivity of Central Solutions in Semidefinite Programming

    NARCIS (Netherlands)

    J.F. Sturm; S. Zhang (Shuzhong)

    1998-01-01

    textabstractIn this paper we study the properties of the analytic central path of a semidefinite programming problem under perturbation of a set of input parameters. Specifically, we analyze the behavior of solutions on the central path with respect to changes on the right hand side of the constrain

  6. Challenges to culturally sensitive care for elderly chinese patients: a first-generation Chinese-American perspective.

    Science.gov (United States)

    Chan, Karen C

    2013-01-01

    Physicians and medical institutions in the United States are placing increasing emphasis on providing culturally sensitive care for patients, such as implementing a Confucian family-based model of medical decision making when caring for elderly Chinese patients. In this article, I articulate various reasons why deferring to the family is not a guarantee of culturally sensitive care, particularly when family members are first-generation Chinese-Americans. Nonetheless, I offer several suggestions to help physicians, medical institutions, and family members to provide more culturally sensitive care for elderly Chinese patients.

  7. Influence of workplace culture on nursing-sensitive nurse outcomes in municipal primary health care.

    Science.gov (United States)

    Hahtela, Nina; Paavilainen, Eija; McCormack, Brendan; Slater, Paul; Helminen, Mika; Suominen, Tarja

    2015-10-01

    To explore the influence of workplace culture on sickness absences, overtime work and occupational injuries in municipal primary health care. The need to improve nursing sensitive outcomes has been highlighted. Therefore, an adequate understanding of the influence of workplace culture on nursing-sensitive nurse outcomes is essential for nurse managers to meet the requirements of improving nursing outcomes. A cross-sectional survey design was used to incorporating the data from 21 inpatient acute care units of nine organisations at the Finnish municipal primary health care system from 2011 to 2012. Findings emphasise in particular the importance of the practice environment as being an interpretative factor for nurses' absences owing to sickness, overtime work and occupational injuries. To ensure favourable nursing sensitive outcomes it is essential that there is a shared interest in the unit to invest in the creation of a supportive practice environment. Outcome improvements require a special focus on issues related to nursing management, adequate staffing and resources and intention to leave. © 2014 John Wiley & Sons Ltd.

  8. Qualitative process evaluation of an Australian alcohol media literacy study: recommendations for designing culturally responsive school-based programs.

    Science.gov (United States)

    Gordon, Chloe S; Kervin, Lisa K; Jones, Sandra C; Howard, Steven J

    2017-02-02

    sensitivities, classroom management challenges, and fitting new programs into already busy school schedules. Overall, the program content and individual lessons were well received by the teachers and students. The lessons learned from the development, implementation and evaluation of this program can provide health professionals with key pedagogical strategies for designing culturally responsive educational programs. Culturally responsive programs are critical for ensuring interventions are effective for their specific context.

  9. Adapting the SRQ for Ethiopian populations: a culturally-sensitive psychiatric screening instrument.

    Science.gov (United States)

    Youngmann, Rafael; Zilber, Nelly; Workneh, Fikre; Giel, Robert

    2008-12-01

    The objective of the study was to develop a culturally sensitive psychiatric screening instrument valid for Ethiopians in Ethiopia and Israel. The study sample was composed of 356 Amharic-speaking Ethiopians from Ethiopia and Israel, aged 18-55, divided into three groups: i) general population; ii) people in non-psychiatric treatment; iii) people in psychiatric treatment. They were interviewed with the Self-Reporting Questionnaire (SRQ), modified to include 10 culturally specific items, and the Brief Psychiatric Research Scale (BPRS) as a criterion of psychopathology. Physicians also completed an encounter form about the presence of mental health symptoms in participants. To make the questions more culturespecific, the translation of 12 items on the SRQ was changed. The content, construct, and criterion validity of each question were also examined, leading to the deletion of five items. The validity of the revised instrument (SRQ-F) was superior to that of the original instrument (SRQ). This study demonstrates the need for psychiatric screening instruments to be adapted to different cultures by incorporating meaningful translations and adding culturally specific items.

  10. Potential programs for high sensitivity FIR spectroscopy with SPICA

    CERN Document Server

    Spinoglio, L; Saraceno, P; Spinoglio, Luigi; Giorgio, Anna Maria Di; Saraceno, Paolo

    2006-01-01

    We discuss the potential of high sensitivity mid-IR and far-IR spectroscopy to proof the physical properties of active nuclei and starburst regions of local and distant galaxies. For local galaxies, it will be possible to map the discs and ISM through the low ionization ionic lines and a variety of molecular tracers, such as OH, H2O and high-J CO. At increasing distance, most of the ionic nebular lines (typical of stars and AGNs) are shifted into the FIR, making possible to compare the observed spectra with those predicted by different evolutionary scenarios. At the very high redshift of 10-15, sensitive mid-to-far-IR spectrometers, such as those planned to be at the focal plane of the future SPICA mision, could be adequate to detect the H recombination lines excited in the HII regions around population III stars, if these stars happened to reside in large clusters of more than 10^5 members.

  11. Learning and Work Programs: Transitional Educative Cultures. Research and Development Series No. 199.

    Science.gov (United States)

    Twarog, Katherine J.; Crowe, Michael R.

    A comparative case study of education and work programs was conducted from an anthropological frame of reference to determine how each sets up a program culture for learners to achieve program goals. Three variables structured into the original research design of the project were (1) the length of the program; (2) the type of community served, and…

  12. Acetylsalicylic acid induces programmed cell death in Arabidopsis cell cultures.

    Science.gov (United States)

    García-Heredia, José M; Hervás, Manuel; De la Rosa, Miguel A; Navarro, José A

    2008-06-01

    Acetylsalicylic acid (ASA), a derivative from the plant hormone salicylic acid (SA), is a commonly used drug that has a dual role in animal organisms as an anti-inflammatory and anticancer agent. It acts as an inhibitor of cyclooxygenases (COXs), which catalyze prostaglandins production. It is known that ASA serves as an apoptotic agent on cancer cells through the inhibition of the COX-2 enzyme. Here, we provide evidences that ASA also behaves as an agent inducing programmed cell death (PCD) in cell cultures of the model plant Arabidopsis thaliana, in a similar way than the well-established PCD-inducing agent H(2)O(2), although the induction of PCD by ASA requires much lower inducer concentrations. Moreover, ASA is herein shown to be a more efficient PCD-inducing agent than salicylic acid. ASA treatment of Arabidopsis cells induces typical PCD-linked morphological and biochemical changes, namely cell shrinkage, nuclear DNA degradation, loss of mitochondrial membrane potential, cytochrome c release from mitochondria and induction of caspase-like activity. However, the ASA effect can be partially reverted by jasmonic acid. Taking together, these results reveal the existence of common features in ASA-induced animal apoptosis and plant PCD, and also suggest that there are similarities between the pathways of synthesis and function of prostanoid-like lipid mediators in animal and plant organisms.

  13. SHORTCUT METHODS FOR SIMPLEX-BASED SENSITIVITY ANALYSIS OF LINEAR PROGRAMMING AND RELATED SOFTWARE ISSUE

    Directory of Open Access Journals (Sweden)

    Muwafaq M. Alkubaisi

    2017-03-01

    Full Text Available This paper has presented an overview of theoretical and methodological issues in simplex based sensitivity analysis (SA. The paper focuses somewhat on developing shortcut methods to perform Linear Programming (L.P. sensitivity analysis manually and in particular to dual prices and its meaning and changes in the parameter of the L.P model. Shortcut methods for conducting sensitivity analysis have been suggested. To perform sensitivity analysis in real life, one needs computer packages (software to achieve the sensitivity analysis report for higher accuracy and to save time. Some of these computer packages are very professional, but, unfortunately, some other packages suffer from logical errors in the programming of sensitivity analysis.

  14. Cultural Competence of Parenting Education Programs Used by Latino Families: A Review

    Science.gov (United States)

    Vesely, Colleen K.; Ewaida, Marriam; Anderson, Elaine A.

    2014-01-01

    The cultural competence of 13 parenting education programs for Latino families with young children was examined in this study. Based on our analyses, we make several recommendations for improving the cultural competence and effectiveness of parenting education programs for Latino families with young children. Specifically, we recommend the…

  15. Cultural Competence of Parenting Education Programs Used by Latino Families: A Review

    Science.gov (United States)

    Vesely, Colleen K.; Ewaida, Marriam; Anderson, Elaine A.

    2014-01-01

    The cultural competence of 13 parenting education programs for Latino families with young children was examined in this study. Based on our analyses, we make several recommendations for improving the cultural competence and effectiveness of parenting education programs for Latino families with young children. Specifically, we recommend the…

  16. University Organizational Culture through Insider Eyes: A Case Study of a Writing Program

    Science.gov (United States)

    Orton, Haley; Conley, Sharon

    2016-01-01

    Using a case study approach, the authors examined university administrator and instructor perspectives about a writing program's organizational culture. In so doing, members of the writing program were invited to participate in interviews over a three-year period. This qualitative case study suggests that examples of culture through a three-lens…

  17. An Evaluation of Sisters of Nia: A Cultural Program for African American Girls

    Science.gov (United States)

    Belgrave, Faye Z.; Reed, Melba C.; Plybon, Laura E.; Butler, Deborah S.; Allison, Kevin W.; Davis, Trina

    2004-01-01

    In this study, the authors evaluated the effectiveness of a cultural intervention for increasing cultural values and beliefs. Fifty-nine African American girls in early adolescence participated in a 15-session cultural program or in an activity comparison group. Measures of ethnic identity, gender roles, and relational aggression were administered…

  18. Faith in the 'cultural fix': limits to a planned cultural change program in a rural health service.

    Science.gov (United States)

    Mahony, K

    2000-01-01

    This paper, by way of a narrative on the author's participation, explains the limits to a planned cultural change program in a large rural health service. Cultural change was identified by the CEO as crucial to the success of a major restructuring of the service, and the attitudes and beliefs of the 'old guard' were considered to be constraining progress. Advocates of cultural integration contend that shared core values across an organisation can overcome such obstacles. This is a matter of faith. An application of Habermasian theory suggests that organisational leaders are drawing on traditional/religious beliefs and practices to bolster their visions and missions at a time of motivational crisis. Though a need for cultural change in some sectors of the health services is acknowledged, the particular challenges in attempting to manipulate the traditionally embedded culture and sub-cultures of the health services is highlighted. An analysis of some of the ideas and beliefs surrounding authority, deference and discipline is undertaken. It is argued that the ritualistic reinforcement of these beliefs and the reproduction of sub-cultures along material and ideal interests militate against the implementation of objectives delineated by the CEO. While cultural analysis has revealed the irrational face of organisations and can bring to conscious awareness the taken-for-granted beliefs which inform behaviour, the cultural integrationists have a further agenda. They aim to manipulate organisational culture to subtly control employees' beliefs and hence behaviour. Cultural control is a covert form of top down authority that can be just as directive and centralizing as bureaucratic control. The author also maintains that cultural change programs alone cannot fix a problem that arose in the macro-economic sphere: a chronic lack of resources ever since the state responded to the economic crisis by cutting funds to health and welfare services.

  19. Mapping Proxy Sensitivity: A New Technique for Compositional Analysis of Cultured Biominerals and Inorganically Precipitated Materials

    Science.gov (United States)

    Gagnon, A. C.; DePaolo, D. J.; DeYoreo, J.; Spero, H. J.; Russell, A. D.

    2011-12-01

    Mineral composition is controlled by a host of environmental factors during precipitation. To build accurate paleo-reconstructions we need to separate the impact of each parameter on proxy behavior and use these data to build a chemical-scale understanding of mineral growth. Biomineral culture and inorganic precipitation experiments, where growth parameters can be manipulated independently, are uniquely suited to calibrate proxies and probe mechanism. Culture and precipitation experiments often involve overgrowth of an initial material. For example, seed crystals are used to control mineralogy and avoid nucleation during inorganic precipitation, while culture experiments in marine organisms typically start with wild specimens. New growth corresponding to the experimental conditions must be resolved from the initial material. Separation is typically achieved using microanalysis, skeletal dissection, or estimates of the initial mass and composition. Each approach imposes limits on the accuracy, precision or types of materials that can be analyzed. Slow growth rates and complicated geometries can make these techniques especially challenging when applied to biominerals. We present a method of compositional analysis for use in biological culture and inorganic growth experiments that overcomes many of these challenges. This method relies on growth in a mixed element stable isotope spike, requires neither the initial mass nor the initial composition to be known, harnesses the precision and sensitivity of bulk analysis, and applies even when it is impossible to physically identify newly grown material. Error analysis suggests this method can significantly improve the precision of metal/calcium measurements in experimentally grown material compared to current methods. Furthermore, the method can isolate different events through time, separating, for example, the impact of day and night cycles on biomineral composition. We will present metal/calcium ratios measured using the

  20. Annexin A2 Modulates Radiation-Sensitive Transcriptional Programming and Cell Fate

    Energy Technology Data Exchange (ETDEWEB)

    Waters, Katrina M.; Stenoien, David L.; Sowa, Marianne B.; von Neubeck, Claere; Chrisler, William B.; Tan, Ruimin; Sontag, Ryan L.; Weber, Thomas J.

    2013-01-01

    There is considerable public interest in the health effects of low doses of radiation (LDR) that fall below the doses that can be plausibly investigated in epidemiological studies. At these low doses, experimental models can detect perturbations in signaling pathways and use this information to define functional consequences of LDR exposures prospectively. In this study, we show increased nuclear annexin A2 (AnxA2) levels in human skin organotypic culture and murine progenitor cell model systems following exposure to X-radiation (10-200 cGy). LDR (2-20 cGy) inhibits cell transformation responses following epidermal growth factor (EGF) or 12-O-tetradecanoylphorbol-13-acetate (TPA) exposures, indicating LDR may have a protective component mediated in part by nuclear localization of AnxA2. Oncogenic protein kinase C epsilon (PKC) levels are increased in nuclear extracts from AnxA2 silenced [shRNA] cells, suggesting that AnxA2 may contribute to PKC nuclear export, perhaps reducing oncogenic potential. Coordinately, silencing AnxA2 results in a sensitive phenotype and cells grow constitutively in soft agar. Using global microarray analysis, we show that silencing AnxA2 fundamentally alters transcriptional programming, changing the radioresponsive transcriptome and revealing biological processes that are induced in the absence of AnxA2. These observations suggest that AnxA2 plays a fundamental role in the sensitivity of cellular and tissue response to ionizing radiation, and deficiency of AnxA2 could result in a permissive environment for radiation-induced health effects.

  1. Pigments for natural dye-sensitized solar cells from in vitro grown shoot cultures

    Science.gov (United States)

    Di Bari, Chiara; Forni, Cinzia; Di Carlo, Aldo; Barrajón-Catalán, Enrique; Micol, Vicente; Teoli, Federico; Nota, Paolo; Matteocci, Fabio; Frattarelli, Andrea; Caboni, Emilia; Lucioli, Simona

    2017-04-01

    In vitro grown shoots cultures (Prunus salicina × Prunus persica), elicited by methyl jasmonate (MJ), are reported here for the first time to prepare a natural dye for dye-sensitized solar cells (DSSC). Redox properties of the dye, its photostability, and light absorption properties suggested it as a candidate as natural photosensitizers for TiO2 photoelectrodes. Redox properties of the dye influence the DSSC production of photocurrent, thus three antioxidant assays were performed in order to characterize the antioxidant potential of this dye. The dye exhibited a high antioxidant activity in all the assays performed. Photostability assay revealed that the dye was quite stable to light. The power conversion efficiency that we obtained (0.53%) was comparable to the data by other authors with anthocyanins-based dyes from in vivo grown plants. Finally, we compared the dye with the partially purified one as photosensitizer in DSSC. The results indicated that the raw pigment from in vitro shoot cultures of P. salicina × P. persica elicited with MJ can be proposed without the needing of any other chemicals, thermal or purification process, or pH adjustments, as a dye for natural sensitized solar cells.

  2. Cultural differences in sensitivity to the relationship between objects and contexts: evidence from P3.

    Science.gov (United States)

    Wang, Kui; Umla-Runge, Katja; Hofmann, Juliane; Ferdinand, Nicola K; Chan, Raymond C K

    2014-06-18

    Cross-cultural differences in Easterners and Westerners have been observed in different cognitive domains. Differential sensitivity to the relationship between objects and contexts might be an underlying cognitive mechanism for these differences. Twenty-one Chinese and 22 Germans participated in a three-stimulus event-related potential oddball task. They were instructed to monitor geometrical forms filled in black (targets) that were presented among a series of blank geometrical forms (standards). Novel stimuli were colored images of common objects. Robust novelty P3 and target P3 over the entire scalp were observed in both groups. As compared with the German group, Chinese participants showed larger amplitudes of novelty P3 and target P3 over frontal regions and earlier peak latency for target P3. This indicates a higher sensitivity to the relationship between contexts and objects in the Chinese as compared with the German group, which might be an underlying mechanism for cross-cultural differences reported in many cognitive domains.

  3. How commercial and ``violent'' video games can promote culturally sensitive science learning: some questions and challenges

    Science.gov (United States)

    Kwah, Helen

    2012-12-01

    In their paper, Muñoz and El-Hani propose to bring video games into science classrooms to promote culturally sensitive ethics and citizenship education. Instead of bringing "educational" games, Muñoz and El-Hani take a more creative route and include games such as Fallout 3® precisely because they are popular and they reproduce ideological and violent representations of gender, race, class, nationality, science and technology. However, there are many questions that arise in bringing these commercial video games into science classrooms, including the questions of how students' capacities for critical reflection can be facilitated, whether traditional science teachers can take on the role of using such games in their classrooms, and which video games would be most appropriate to use. In this response, I raise these questions and consider some of the challenges in order to further the possibility of implementing Muñoz and El-Hani's creative proposal for generating culturally sensitive science classrooms.

  4. Investing in organisational culture: nursing students' experience of organisational learning culture in aged care settings following a program of cultural development.

    Science.gov (United States)

    Grealish, Laurie; Henderson, Amanda

    2016-10-01

    Concerns around organisational learning culture limit nursing student placements in aged care settings to first year experiences. Determine the impact of an extended staff capacity building program on students' experiences of the organisational learning culture in the aged care setting. Pre and post-test design. A convenience sample of first, second and third year Bachelor of Nursing students attending placements at three residential aged care facilities completed the Clinical Learning Organisational Culture Survey. Responses between the group that attended placement before the program (n = 17/44; RR 38%) and the group that attended following the program (n = 33/72; RR 45%) were compared. Improvements were noted in the areas of recognition, accomplishment, and influence, with decreases in dissatisfaction. Organisational investment in building staff capacity can produce a positive learning culture. The aged care sector offers a rich learning experience for students when staff capacity to support learning is developed.

  5. A rapid and sensitive method for measuring N-acetylglucosaminidase activity in cultured cells.

    Directory of Open Access Journals (Sweden)

    Victor Mauri

    Full Text Available A rapid and sensitive method to quantitatively assess N-acetylglucosaminidase (NAG activity in cultured cells is highly desirable for both basic research and clinical studies. NAG activity is deficient in cells from patients with Mucopolysaccharidosis type IIIB (MPS IIIB due to mutations in NAGLU, the gene that encodes NAG. Currently available techniques for measuring NAG activity in patient-derived cell lines include chromogenic and fluorogenic assays and provide a biochemical method for the diagnosis of MPS IIIB. However, standard protocols require large amounts of cells, cell disruption by sonication or freeze-thawing, and normalization to the cellular protein content, resulting in an error-prone procedure that is material- and time-consuming and that produces highly variable results. Here we report a new procedure for measuring NAG activity in cultured cells. This procedure is based on the use of the fluorogenic NAG substrate, 4-Methylumbelliferyl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (MUG, in a one-step cell assay that does not require cell disruption or post-assay normalization and that employs a low number of cells in 96-well plate format. We show that the NAG one-step cell assay greatly discriminates between wild-type and MPS IIIB patient-derived fibroblasts, thus providing a rapid method for the detection of deficiencies in NAG activity. We also show that the assay is sensitive to changes in NAG activity due to increases in NAGLU expression achieved by either overexpressing the transcription factor EB (TFEB, a master regulator of lysosomal function, or by inducing TFEB activation chemically. Because of its small format, rapidity, sensitivity and reproducibility, the NAG one-step cell assay is suitable for multiple procedures, including the high-throughput screening of chemical libraries to identify modulators of NAG expression, folding and activity, and the investigation of candidate molecules and constructs for applications in

  6. Is there a genetic contribution to cultural differences? Collectivism, individualism and genetic markers of social sensitivity.

    Science.gov (United States)

    Way, Baldwin M; Lieberman, Matthew D

    2010-06-01

    Genes and culture are often thought of as opposite ends of the nature-nurture spectrum, but here we examine possible interactions. Genetic association studies suggest that variation within the genes of central neurotransmitter systems, particularly the serotonin (5-HTTLPR, MAOA-uVNTR) and opioid (OPRM1 A118G), are associated with individual differences in social sensitivity, which reflects the degree of emotional responsivity to social events and experiences. Here, we review recent work that has demonstrated a robust cross-national correlation between the relative frequency of variants in these genes and the relative degree of individualism-collectivism in each population, suggesting that collectivism may have developed and persisted in populations with a high proportion of putative social sensitivity alleles because it was more compatible with such groups. Consistent with this notion, there was a correlation between the relative proportion of these alleles and lifetime prevalence of major depression across nations. The relationship between allele frequency and depression was partially mediated by individualism-collectivism, suggesting that reduced levels of depression in populations with a high proportion of social sensitivity alleles is due to greater collectivism. These results indicate that genetic variation may interact with ecological and social factors to influence psychocultural differences.

  7. Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes.

    Science.gov (United States)

    Jung, Daun; Che, Jeong-Hwan; Lim, Kyung-Min; Chun, Young-Jin; Heo, Yong; Seok, Seung Hyeok

    2016-09-01

    In vitro testing methods for classifying sensitizers could be valuable alternatives to in vivo sensitization testing using animal models, such as the murine local lymph node assay (LLNA) and the guinea pig maximization test (GMT), but there remains a need for in vitro methods that are more accurate and simpler to distinguish skin sensitizers from non-sensitizers. Thus, the aim of our study was to establish an in vitro assay as a screening tool for detecting skin sensitizers using the human keratinocyte cell line, HaCaT. HaCaT cells were exposed to 16 relevant skin sensitizers and 6 skin non-sensitizers. The highest dose used was the dose causing 75% cell viability (CV75) that we determined by an MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. The levels of extracellular production of interleukin-1α (IL-1α) and IL-6 were measured. The sensitivity of IL-1α was 63%, specificity was 83% and accuracy was 68%. In the case of IL-6, sensitivity: 69%, specificity: 83% and accuracy: 73%. Thus, this study suggests that measuring extracellular production of pro-inflammatory cytokines IL-1α and IL-6 by human HaCaT cells may potentially classify skin sensitizers from non-sensitizers. Copyright © 2015 John Wiley & Sons, Ltd.

  8. What's culture got to do with it? Prevention programs for African American adolescent girls.

    Science.gov (United States)

    Corneille, Maya A; Ashcroft, Amie M; Belgrave, Faye Z

    2005-11-01

    This paper examines prevention programming for African American girls by placing the prevention process within the larger African and African American cultural context. We provide an overview of the theories and issues we consider most relevant to African American culture, including Africentric theory, ethnic identity, gender identity and relational theory, developmental issues, the community context, and historical considerations. Drawing from our own drug prevention work, we provide examples of how to incorporate culture into prevention programs to make them most relevant for the target population. We also summarize our own efforts to create culturally appropriate prevention interventions and their impact on the girls in our programs. We conclude with suggested directions for future research into culture-specific prevention programs.

  9. Standing Strong: Maloney Interdistrict Magnet School Japanese Language and Culture Program

    Science.gov (United States)

    Haxhi, Jessica; Yamashita-Iverson, Kazumi

    2009-01-01

    Maloney Interdistrict Magnet School (MIMS) is the only elementary school in Waterbury that has a world language program and is one of only two elementary Japanese programs in Connecticut. In the past 15 years, more than 1500 students have participated in its Japanese Language and Culture (JLC) Program in grades Prekindergarten through 5th. The JLC…

  10. Evaluation on Sensitivity of the Human Sperm Motility Assay for Detecting Endotoxin in Culture Medium

    Institute of Scientific and Technical Information of China (English)

    Wei-jie ZHU; Jing LI; Wen-hong ZHANG; Kang-shou YAO

    2003-01-01

    Objective To investigate the sensitivity of the human sperm motility assay for detecting endotoxin in culture medium Materials & Methods Motile sperm were separated and exposed to different concentrations of endotoxin (0.5 ng/mL, 1 ng/mL, 10 ng/mL, 1 000 ng/mL, 10 000 ng/mL, and 50 000 ng/mL), and sperm motility was determined after incubation. Effects of endotoxin on sperm motility in media without albumin were also examined. In addition, at the same concentrations of endotoxin (0.5 ng/mL, 1 ng/mL, and 10 ng/mL), the sensitivity of the human sperm motility assay was compared to those of 1-cell and 2-cell mouse embryo bioassays.Results At levels of 0.5 ng/mL~1 000 ng/mL endotoxin in media with 2 mg/mL albumin, sperm did not show significant change in motility during 24 h of incubation when compared with the control (P>0.05). However, the sperm motility was significantly inhibited at endotoxin dosages of 10 000 and 50 000 ng/mL. In the absence of albumin supplementation, at endotoxin levels of 50 000 ng/mL, and 1 000 ng/mL, there was a marked decrease in sperm motility compared with the control after 2 h or 8 h of incubation, respectively (P<0.01). In media containing 0.5 ng/mL and 1 ng/mL endotoxin, 1-cell and 2-cell mouse embryos had significantly reduced developmental rates in all developmental stages, and at the level of 10 ng/mL, the development of the embryos was arrested.Conclusion The human sperm motility assay could detect high levels of endotoxin in culture medium but its sensitivity to endotoxin would be inferior to that of the 1-cell or 2-cell mouse embryo bioassay. In the absence of albumin supplementation, the sensitivity of the sperm motility assay could be improved.

  11. A Sensitive Competitive ELISA for Determination of Biotin in Transformed Yeast Culture Media

    Institute of Scientific and Technical Information of China (English)

    YANGHong

    2003-01-01

    Aim To develop a sensitive competitive ELISA for the determination of biotin in transformed yeast culture media.Methods The ELISA plate was firstly coated with Mycoplasma hyopneumoniae, and then successively incubated with rabbit ami-Mycoplasma hyopneumoniae serum and goat anti-rabbit IgG-biotin to form the solid biotin, which competed with the biotin in the solution (standard or sample) for the limited streptavidin-horse radish peroxidase conjugate. The standard calibration curve for biotin analysis was constructed in the range of 50-2000ng·L-1. Results The detection limit for biotin was found to be 83 ng·L-1 , which waa about 1000 times lower than the lowest determination concenlration in the reported ELISA for biotin analysis. The relative standard deviations for the spiked samples at biotin concerarations of 200 ng·L-1, 500 ng·L-1 , and 1000 ng·L-1 were 24.87%, 6.15%, and 7.86%, respectively, with the average recovery of 101.13%. The wild yeast and its sixty-three transformed yeast culture media were applied to the developed ELISA for the determination of biotin. It was found that the biotin concentrations in more than 85 % of the tested samples were enhanced with different increase factors after transformation. Conclusion Utilization of Mycoplasma hyopnetunoniae as the coating protein improves the precision and accmacy oftbe ELISA assay, which might be used for the biotin assay in other media.

  12. Development and Validation of Culture-Sensitive Physics Learning Environment Survey (CS-PLES

    Directory of Open Access Journals (Sweden)

    Marie Paz E. Morales

    2014-05-01

    Full Text Available The study combined qualitative approaches with quantitative research design to come up with a survey instrument called Culture-Sensitive Physics Learning Environment Survey (CS-PLES.This survey instrument is intended to extract the learners’ beliefs and expectations on the integration of culture and language in the teaching and learning process of physics concepts. Significant contribution of the instrument can be traced to establishing and defining the constructs and categories on how curriculum localization and context-based science learning can be developed aligned with students’ expectations and beliefs. The development process employed non-conventional processes adopted from literature which included pilot study to identify pre-deterministic constructs and specific categories for the items to be included in the survey. Data analysis included descriptive statistics and factor analysis to establish the categories or constructs of the survey instruments. Reliability measures of the instrument and its respective constructs were established for standardization. These categories were intended to aid researchers for an in-depth analysis when the instrument is administered for its purpose. The raw statistical categories were qualitatively paralleled with the pre-deterministic constructs to establish congruence of the survey tool to Instructional Congruence Framework (ICF.

  13. NRSF causes cAMP-sensitive suppression of sodium current in cultured hippocampal neurons

    Science.gov (United States)

    Nadeau, H.; Lester, H. A.

    2002-01-01

    The neuron restrictive silencer factor (NRSF/REST) has been shown to bind to the promoters of many neuron-specific genes and is able to suppress transcription of Na(+) channels in PC12 cells, although its functional effect in terminally differentiated neurons is unknown. We constructed lentiviral vectors to express NRSF as a bicistronic message with green fluorescent protein (GFP) and followed infected hippocampal neurons in culture over a period of 1-2 wk. NRSF-expressing neurons showed a time-dependent suppression of Na(+) channel function as measured by whole cell electrophysiology. Suppression was reversed or prevented by the addition of membrane-permeable cAMP analogues and enhanced by cAMP antagonists but not affected by increasing protein expression with a viral enhancer. Secondary effects, including altered sensitivity to glutamate and GABA and reduced outward K(+) currents, were duplicated by culturing GFP-infected control neurons in TTX. The striking similarity of the phenotypes makes NRSF potentially useful as a genetic "silencer" and also suggests avenues of further exploration that may elucidate the transcription factor's in vivo role in neuronal plasticity.

  14. [Home care in a culturally sensitive environment: perspectives of caregivers of Haitian elderly patients and relatives].

    Science.gov (United States)

    Ducharme, Francine; Paquet, Mario; Vissandjée, Bilkis; Carpentier, Normand; Lévesque, Louise; Trudeau, Denise

    2008-01-01

    In Canada, the care provided by families occurs in an increasingly multiethnic context. Against this backdrop, the present qualitative study aims to explore the needs/expectations and solutions not only of (female) natural caregivers of an elderly relative hailing from Haiti (presented in terms of tracking cases) but also of remunerated home care providers - all with a view to developing a culturally sensitive service offering. As such, this study works from a conceptual framework centring on the negotiation of a common area of agreement between the stakeholders involved (i.e., natural caregivers and home care providers). To this end, focus groups and individual interviews were conducted among 15 caregivers and 37 home care providers. The three recurrent themes emerging from the data analysis concern, in context, the needs/expectations and solutions surrounding the experience of service use, barriers to use, and the relationships between natural caregivers and home care providers. The statements of both groups evidenced a consistency of views and have thus provided a basis for developing some recommendations acceptable to all stakeholders from the perspective of making culturally-based adjustments to the service offering.

  15. Isolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul.

    Science.gov (United States)

    Eser, Ilker; Kapran, Ziya; Altan, Tugrul; Ozel Karatas, Meltem; Aydin, Derya; Okaygun, Eda; Yilmaz, Omer Faruk

    2008-01-01

    To investigate the spectrum of organisms causing endophthalmitis and their sensitivity to commonly used antimicrobial agents. Medical records of 80 consecutive patients treated at Beyoglu Eye Hospital for endophthalmitis from January 2001 to April 2006 were reviewed. Specimens were obtained from either the vitreous (93%, 81/87) or anterior chamber (7%, 6/87) during pars plana vitrectomy or vitreous tap, and were inoculated into blood culture bottles. A Kirby-Bauer disk diffusion test was performed to determine antibiotic susceptibility. The outcome measures included isolates identified and antibiotic sensitivity of the specimens. Fifty-six of 87 (64.4%) isolates were Gram-positive organisms, 29 (33.3%) were Gram-negative organisms, and 2 (2.3%) were fungi. The most common organism group identified was coagulase-negative staphylococci in 26.4% (23/87). While vancomycin was active against all Gram-positive isolates tested (100%), ceftazidime had the highest susceptibility rate (100%) for Gram-negative organisms isolated. Although coagulase-negative micrococci predominated in this series, a high isolation rate for Gram-negative organisms was obtained. High susceptibility rates for ofloxacin make it an alternative to ceftazidime and vancomycin in both Gram-negative- and Gram-positive-derived endophthalmitis, respectively. Studies with larger series and additional antibiotics are needed to confirm these findings. (c) 2008 S. Karger AG, Basel

  16. Potential interactions of calcium-sensitive reagents with zinc ion in different cultured cells.

    Science.gov (United States)

    Fujikawa, Koichi; Fukumori, Ryo; Nakamura, Saki; Kutsukake, Takaya; Takarada, Takeshi; Yoneda, Yukio

    2015-01-01

    Several chemicals have been widely used to evaluate the involvement of free Ca(2+) in mechanisms underlying a variety of biological responses for decades. Here, we report high reactivity to zinc of well-known Ca(2+)-sensitive reagents in diverse cultured cells. In rat astrocytic C6 glioma cells loaded with the fluorescent Ca(2+) dye Fluo-3, the addition of ZnCl2 gradually increased the fluorescence intensity in a manner sensitive to the Ca(2+) chelator EGTA irrespective of added CaCl2. The addition of the Ca(2+) ionophore A23187 drastically increased Fluo-3 fluorescence in the absence of ZnCl2, while the addition of the Zn(2+) ionophore pyrithione rapidly and additionally increased the fluorescence in the presence of ZnCl2, but not in its absence. In cells loaded with the zinc dye FluoZin-3 along with Fluo-3, a similarly gradual increase was seen in the fluorescence of Fluo-3, but not of FluoZin-3, in the presence of both CaCl2 and ZnCl2. Further addition of pyrithione drastically increased the fluorescence intensity of both dyes, while the addition of the Zn(2+) chelator N,N,N',N'-tetrakis(2-pyridylmethyl)ethane-1,2-diamine (TPEN) rapidly and drastically decreased FluoZin-3 fluorescence. In cells loaded with FluoZin-3 alone, the addition of ZnCl2 induced a gradual increase in the fluorescence in a fashion independent of added CaCl2 but sensitive to EGTA. Significant inhibition was found in the vitality to reduce 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide in a manner sensitive to TPEN, EDTA and BAPTA in C6 glioma cells exposed to ZnCl2, with pyrithione accelerating the inhibition. Similar inhibition occurred in an EGTA-sensitive fashion after brief exposure to ZnCl2 in pluripotent P19 cells, neuronal Neuro2A cells and microglial BV2 cells, which all expressed mRNA for particular zinc transporters. Taken together, comprehensive analysis is absolutely required for the demonstration of a variety of physiological and pathological responses

  17. Cross-Cultural Perspectives After Participation in the YES Program: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Vanessa E. Fuentes

    2016-05-01

    Full Text Available Abstract:  Guided by empowerment and ecological theories, the Youth Empowerment Solutions (YES program facilitates character development through activities based in cultural differences, team building, and social change. This pilot study consisted of two focus groups (n = 13 of middle school youth conducted after their participation in an abbreviated version of the YES program. Specifically, the present study examined youth’s cross-cultural perspectives after participation. The focus groups were transcribed and coded for emergent themes using Heaton’s (2005 supplementary data analysis framework. Qualitative analysis resulted in two emergent themes: 1 enhanced appreciation for similarities and differences in cultural and ethnic backgrounds, and 2 the role of respect in understanding differences and confronting stereotypes. Specifically, youth reported that engagement in this program fostered positive awareness of cultural differences and respect for inter-ethnic relationships. The findings provide support for the benefits of the YES program on moral development and promotion of healthy peer relationships.

  18. Developmental Idealism: The Cultural Foundations of World Development Programs.

    Science.gov (United States)

    Thornton, Arland; Dorius, Shawn F; Swindle, Jeffrey

    2015-01-01

    This paper extends theory and research concerning cultural models of development beyond family and demographic matters to a broad range of additional factors, including government, education, human rights, daily social conventions, and religion. Developmental idealism is a cultural model-a set of beliefs and values-that identifies the appropriate goals of development and the ends for achieving these goals. It includes beliefs about positive cause and effect relationships among such factors as economic growth, educational achievement, health, and political governance, as well as strong values regarding many attributes, including economic growth, education, small families, gender equality, and democratic governance. This cultural model has spread from its origins among the elites of northwest Europe to elites and ordinary people throughout the world. Developmental idealism has become so entrenched in local, national, and global social institutions that it has now achieved a taken-for-granted status among many national elites, academics, development practitioners, and ordinary people around the world. We argue that developmental idealism culture has been a fundamental force behind many cultural clashes within and between societies, and continues to be an important cause of much global social change. We suggest that developmental idealism should be included as a causal factor in theories of human behavior and social change.

  19. Developmental Idealism: The Cultural Foundations of World Development Programs

    Science.gov (United States)

    Thornton, Arland; Dorius, Shawn F.; Swindle, Jeffrey

    2015-01-01

    This paper extends theory and research concerning cultural models of development beyond family and demographic matters to a broad range of additional factors, including government, education, human rights, daily social conventions, and religion. Developmental idealism is a cultural model—a set of beliefs and values—that identifies the appropriate goals of development and the ends for achieving these goals. It includes beliefs about positive cause and effect relationships among such factors as economic growth, educational achievement, health, and political governance, as well as strong values regarding many attributes, including economic growth, education, small families, gender equality, and democratic governance. This cultural model has spread from its origins among the elites of northwest Europe to elites and ordinary people throughout the world. Developmental idealism has become so entrenched in local, national, and global social institutions that it has now achieved a taken-for-granted status among many national elites, academics, development practitioners, and ordinary people around the world. We argue that developmental idealism culture has been a fundamental force behind many cultural clashes within and between societies, and continues to be an important cause of much global social change. We suggest that developmental idealism should be included as a causal factor in theories of human behavior and social change. PMID:26457325

  20. The Training and Culture Strategies in the CIMS Subject of China 863 Program(1986-2000)

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Manpower is a key factor for the success of the CIMS Subject of China 863 Program. Many manpower strategies have been used in the CIMS Subject, which include elite strategies, training and practicing strategies, and culture strategies. This paper is mainly about the training and culture strategies such as to pay attention to the training and the practice of the technical team, and to form a fine CIMS culture.

  1. Effects of a Culturally Adapted Social-Emotional Learning Intervention Program on Students' Mental Health

    Science.gov (United States)

    Cramer, Kristine M.; Castro-Olivo, Sara

    2016-01-01

    Student self-reports of resiliency and social-emotional internalizing problems were examined to determine intervention effects of a culturally adapted social and emotional learning (SEL) program. Data were analyzed from 20 culturally and linguistically diverse high school students who participated in a school-based 12-lesson SEL intervention and…

  2. Evaluation of the Cultural and Creative Arts Program in Monongalia County (June 12-July 14, 1967).

    Science.gov (United States)

    Hofstetter, Arthur N.; Peltonen, Jean

    The second session of a proposed 3-year annual summer Cultural and Creative Arts Program was held in 6 selected Monongalia County, West Virginia, schools for first- through sixth-grade pupils. Objectives were to emphasize the distinctive cultural character of Appalachia and to emphasize exploration and experimentation rather than mastery of formal…

  3. Sensitivity of solid culture, broth culture, and real-time PCR assays for milk and colostrum samples from Mycobacterium avium ssp. paratuberculosis-infectious dairy cows.

    Science.gov (United States)

    Laurin, Emilie; McKenna, Shawn; Chaffer, Marcelo; Keefe, Greg

    2015-12-01

    Mycobacterium avium ssp. paratuberculosis (MAP) can be shed in feces, milk, and colostrum. The goal of this study was to assess assays that detect MAP in these sample types, including effects of lactation stage or season. Understanding the performance of these assays could improve how they are used, limiting the risk of infection to calves. Forty-six previously confirmed MAP-positive cows from 7 Atlantic Canadian dairy farms were identified for colostrum sampling and monthly sampling of milk and feces over a 12-mo period. Samples were assayed for MAP using solid culture, broth culture, and direct real-time PCR (qPCR). Across assay types, test sensitivity when applied to milk samples averaged 25% of that when applied to fecal samples. For colostrum samples, sensitivity depended on assay type, with sensitivity of qPCR being approximately 46% of that in feces. Across sample types, sensitivity of qPCR was higher than that of the other assays. Sensitivity of qPCR, when applied to milk samples, was significantly higher in summer than in other seasons. Summer was also the season with highest agreement between milk and fecal samples collected within the same month. Our results suggest that qPCR would detect more cows shedding MAP in their milk and colostrum than solid or broth culture assays, particularly during the summer, thus providing better management information to limit exposure of calves to this infectious organism.

  4. THE INFLUENCE OF CULTURE ON MARKETING PROGRAMS FOR NEW PRODUCTS LAUNCH

    Directory of Open Access Journals (Sweden)

    Gabriela CĂPĂȚÎNĂ

    2014-11-01

    Full Text Available This article attempts to analyze the influence of culture on marketing programs for new products launch. Despite the special attention that literature confers to new products, the tactical side represented by marketing program which operationalize the new product launch, it is strongly neglected. Thus, considering the actual trends toward international markets and the existing gap in literature, the paper sections will treat the culture components in relation with marketing program activities developed for a new product launch. The contribution of this paper at scientific progress is accomplished by providing detailed descriptions of changes occurred in marketing programs in cultural diversity context; it is a preamble for a field which need new developments, theories and knowledge. In terms of conclusions, marketing program on international market is expected to be a good predictor of new product success, and at the same time, a useful approach to optimize the allocation of marketing effort.

  5. A fast and highly sensitive blood culture PCR method for clinical detection of Salmonella enterica serovar Typhi

    Directory of Open Access Journals (Sweden)

    Zhou Liqing

    2010-04-01

    Full Text Available Abstract Background Salmonella Typhi causes an estimated 21 million new cases of typhoid fever and 216,000 deaths every year. Blood culture is currently the gold standard for diagnosis of typhoid fever, but it is time-consuming and takes several days for isolation and identification of causative organisms. It is then too late to initiate proper antibiotic therapy. Serological tests have very low sensitivity and specificity, and no practical value in endemic areas. As early diagnosis of the disease and prompt treatment are essential for optimal management, especially in children, a rapid sensitive detection method for typhoid fever is urgently needed. Although PCR is sensitive and rapid, initial research indicated similar sensitivity to blood culture and lower specificity. We developed a fast and highly sensitive blood culture PCR method for detection of Salmonella Typhi, allowing same-day initiation of treatment after accurate diagnosis of typhoid. Methods An ox bile tryptone soy broth was optimized for blood culture, which allows the complete lysis of blood cells to release intracellular bacteria without inhibiting the growth of Salmonella Typhi. Using the optimised broth Salmonella Typhi bacteria in artificial blood samples were enriched in blood culture and then detected by a PCR targeting the fliC-d gene of Salmonella Typhi. Results Tests demonstrated that 2.4% ox bile in blood culture not only lyzes blood cells completely within 1.5 hours so that the intracellular bacteria could be released, but also has no inhibiting effect on the growth of Salmonella Typhi. Three hour enrichment of Salmonella Typhi in tryptone soya broth containing 2.4% ox bile could increase the bacterial number from 0.75 CFU per millilitre of blood which is similar to clinical typhoid samples to the level which regular PCR can detect. The whole blood culture PCR assay takes less than 8 hours to complete rather than several days for conventional blood culture

  6. The Cultural-Historical Basis of the "Golden Key" Program

    Science.gov (United States)

    Kravtsov, Genady G.; Kravtsova, Elena E.

    2011-01-01

    The "Golden Key" programme is a preschool education programme that is constructed on the basis of Vygotskij's cultural-historical theory. One of the most important aspects of this theory is not just the unity of intellect and affect, but the fact that the relationship between these two changes during the course of development. In infants, affect…

  7. Key Factors for Developing a Cross-Cultural Education Program

    Science.gov (United States)

    Yang, Keeyung; Chung, Sock H.

    2015-01-01

    Purpose: As universities and colleges face an increasingly global environment, internationalization is viewed as a critical aspect of education, a fact that has significant academic and economic implications for higher educational institutions worldwide which need to be current with cultural education to adapt to change. Learning from other…

  8. Sensitizing Children to the Social and Emotional Mechanisms Involved in Racism: A Program Evaluation

    Science.gov (United States)

    Triliva, Sofia; Anagnostopoulou, Tanya; Vleioras, Georgios

    2014-01-01

    This paper describes and discusses the results of an intervention aiming to sensitize children to the social and emotional processes involved in racism. The intervention was applied and evaluated in 10 Greek elementary schools. The goals and the intervention methods of the program modules are briefly outlined and the results of the program…

  9. Investigating the Reliability and Validity of Chen and Starosta’s Intercultural Sensitivity Scale (ISS) against Chinese Cultural Background

    Institute of Scientific and Technical Information of China (English)

    刘涵; Salasiah Che Lah

    2013-01-01

    Intercultural Communication Competence (ICC), as one of the research ifelds of intercultural communication, has been given much importance from scholars all around the world. Intercultural sensitivity is one of the three dimensions in Dr Chen’s ICC model. This research investigates the reliability and validity of Chen and Starosta’s Intercultural Sensitivity Scale (ISS) (2000) against Chinese cultural background by using Chinese university students majoring in English as respondents.

  10. Sr/Ca Sensitivity to Aragonite Saturation in Cultured Coral Measured by NanoSIMS (Invited)

    Science.gov (United States)

    Gagnon, A. C.; Adkins, J. F.; Erez, J.

    2010-12-01

    NanoSIMS was used to identify and com¬positionally characterize the micron scale region of skeletal growth resulting from a short coral culture experiment. Using this technique we quantify the sensitivity of Sr/Ca, a proxy for temperature, to aragonite saturation (Ω), a parameter that varied in the past ocean and is predicted to change with continued ocean acidification. Five adult branches of the surface coral Stylophora sp. were all grown at 25 °C but at different and near constant carbonate ion concentrations, from 180 to 400 µM (pH of 7.9 to 8.5), yielding a two-fold range in calcification rate. Despite the range of Ωs and calcification rates, the average Sr/Ca of nanoSIMS spot measurements corresponding to each condition are within 1.2% (2σ std. dev. of the 5 means). Furthermore, the average Sr/Ca measured in this study agrees with two previous coral culture experiments conducted at the same temperature but where Ω was not controlled. These results suggest carbonate ion concentration is not a complicating factor to Sr/Ca paleothermometry over this range of Ω. Within the framework of a closed system (Rayleigh) model for biomineralization, similar Sr/Ca ratios suggest similar amounts of Rayleigh fractionation. Combined with existing data for low Ω conditions, the extent of Rayleigh fractionation is used to test alternative biomineralization models governing the acid-base chemistry of the calcifying fluid. Assuming that coral use alkalinity pumping to increase local calcifying fluid carbonate ion concentration, we try to understand what controls this pumping. Under most conditions, Sr/Ca ratios are consistent with a scenario where calcifying fluid alkalinity increases until reaching a target pH. However, under conditions of very low seawater Ω, coral cannot pump enough alkalinity to reach the target pH. Below this threshold value, between approximately 1<Ω<2.4, coral pump a maximal and finite amount of alkalinity. The interaction between these rules

  11. Robust optimization for nonlinear time-delay dynamical system of dha regulon with cost sensitivity constraint in batch culture

    Science.gov (United States)

    Yuan, Jinlong; Zhang, Xu; Liu, Chongyang; Chang, Liang; Xie, Jun; Feng, Enmin; Yin, Hongchao; Xiu, Zhilong

    2016-09-01

    Time-delay dynamical systems, which depend on both the current state of the system and the state at delayed times, have been an active area of research in many real-world applications. In this paper, we consider a nonlinear time-delay dynamical system of dha-regulonwith unknown time-delays in batch culture of glycerol bioconversion to 1,3-propanediol induced by Klebsiella pneumonia. Some important properties and strong positive invariance are discussed. Because of the difficulty in accurately measuring the concentrations of intracellular substances and the absence of equilibrium points for the time-delay system, a quantitative biological robustness for the concentrations of intracellular substances is defined by penalizing a weighted sum of the expectation and variance of the relative deviation between system outputs before and after the time-delays are perturbed. Our goal is to determine optimal values of the time-delays. To this end, we formulate an optimization problem in which the time delays are decision variables and the cost function is to minimize the biological robustness. This optimization problem is subject to the time-delay system, parameter constraints, continuous state inequality constraints for ensuring that the concentrations of extracellular and intracellular substances lie within specified limits, a quality constraint to reflect operational requirements and a cost sensitivity constraint for ensuring that an acceptable level of the system performance is achieved. It is approximated as a sequence of nonlinear programming sub-problems through the application of constraint transcription and local smoothing approximation techniques. Due to the highly complex nature of this optimization problem, the computational cost is high. Thus, a parallel algorithm is proposed to solve these nonlinear programming sub-problems based on the filled function method. Finally, it is observed that the obtained optimal estimates for the time-delays are highly satisfactory

  12. Different sensitivities of cultured mammalian cells towards aphidicolin-enhanced DNA effects in the comet assay.

    Science.gov (United States)

    Speit, Günter; Schütz, Petra; Bausinger, Julia

    2016-06-01

    The comet assay in combination with the polymerase inhibitor aphidicolin (APC) has been used to measure DNA excision repair activity, DNA repair kinetics and individual DNA repair capacity. Since APC can enhance genotoxic effects of mutagens measured by the comet assay, this approach has been proposed for increasing the sensitivity of the comet assay in human biomonitoring. The APC-modified comet assay has mainly been performed with human blood and it was shown that it not only enhances the detection of DNA damage repaired by nucleotide excision repair (NER) but also damage typically repaired by base excision repair (BER). Recently, we reported that in contrast to blood leukocytes, A549 cells (a human lung adenocarcinoma cell line) seem to be insensitive towards the repair-inhibiting action of APC. To further elucidate the general usefulness of the APC-modified comet assay for studying repair in cultured mammalian cells, we comparatively investigated further cell lines (HeLa, TK6, V79). DNA damage was induced by BPDE (benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide) and MMS (methyl methanesulfonate) in the absence and presence of APC (3 or 15μM). APC was either added for 2h together with the mutagen or cells were pre-incubated for 30min with APC before the mutagen was added. The results indicate that the cell lines tested differ fundamentally with regard to their sensitivity and specificity towards the repair-inhibiting effect of APC. The actual cause for these differences is still unclear but potential molecular explanations are discussed. Irrespective of the underlying mechanism(s), our study revealed practical limitations of the use of the APC-modified comet assay.

  13. Media, Tourism, Environment, and Cultural Issues in Australia: A Case Study of a Study Abroad Program

    Science.gov (United States)

    Freedman, Eric

    2010-01-01

    A multidisciplinary study abroad program developed by a U.S. journalism school and cosponsored by a college of agriculture and natural resources interweaves the themes of mass media, tourism, environment, and cultural issues in Australia. This article traces the development and evolution of the faculty-led program and discusses its curriculum,…

  14. Learning from Popular Culture: The "Politics" of Competitive Reality Television Programs

    Science.gov (United States)

    Dreyer, David R.

    2011-01-01

    Reality television programming has become a pervasive part of popular culture. Although such programming may seem to be mindless entertainment, it can serve as a tool to introduce political lessons in the classroom. This article examines how the concepts of alliance behavior and strategic voting can be explored by using the television program…

  15. 75 FR 34519 - Bureau of Educational and Cultural Affairs; U.S. Professional Development Program for...

    Science.gov (United States)

    2010-06-17

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF STATE Bureau of Educational and Cultural Affairs; U.S. Professional Development Program for EducationUSA Advisers... Grant Proposals (RFGP) for the U.S. Professional Development Program for EducationUSA...

  16. Media, Tourism, Environment, and Cultural Issues in Australia: A Case Study of a Study Abroad Program

    Science.gov (United States)

    Freedman, Eric

    2010-01-01

    A multidisciplinary study abroad program developed by a U.S. journalism school and cosponsored by a college of agriculture and natural resources interweaves the themes of mass media, tourism, environment, and cultural issues in Australia. This article traces the development and evolution of the faculty-led program and discusses its curriculum,…

  17. Application of ImageJ program to the enumeration of Orientia tsutsugamushi organisms cultured in vitro.

    Science.gov (United States)

    Siritantikorn, Sontana; Jintaworn, Suthatip; Noisakran, Sansanee; Suputtamongkol, Yupin; Paris, Daniel H; Blacksell, Stuart D

    2012-10-01

    The ImageJ program was applied to the enumeration of Orientia tsutsugamushi organisms in cell culture using indirect immunofluorescence assay (IFA). The highest correlation (r=0.984) was observed between manual counting methods and the ImageJ program (MaxEntropy threshold algorithm). This software-based methodology is cheaper, more standardised and better reproducible than a manual-based approach.

  18. The role of culture in substance abuse treatment programs for American Indian and Alaska Native communities.

    Science.gov (United States)

    Legha, Rupinder Kaur; Novins, Douglas

    2012-07-01

    Culture figures prominently in discussions regarding the etiology of alcohol and substance abuse in American Indian and Alaska Native (AI/AN) communities, and a substantial body of literature suggests that it is critical to developing meaningful treatment interventions. However, no study has characterized how programs integrate culture into their services. Furthermore, reports regarding the associated challenges are limited. Twenty key informant interviews with administrators and 15 focus groups with clinicians were conducted in 18 alcohol and substance abuse treatment programs serving AI/AN communities. Transcripts were coded to identify relevant themes. Substance abuse treatment programs for AI/AN communities are integrating culture into their services in two discrete ways: by implementing specific cultural practices and by adapting Western treatment models. More important, however, are the fundamental principles that shape these programs and their interactions with the people and communities they serve. These foundational beliefs and values, defined in this study as the core cultural constructs that validate and incorporate AI/AN experience and world view, include an emphasis on community and family, meaningful relationships with and respect for clients, a homelike atmosphere within the program setting, and an “open door” policy for clients. The primary challenges for integrating these cultural practices include AI/AN communities' cultural diversity and limited socioeconomic resources to design and implement these practices. The prominence of foundational beliefs and values is striking and suggests a broader definition of culture when designing services. This definition of foundational beliefs and values should help other diverse communities culturally adapt their substance abuse interventions in more meaningful ways.

  19. The appearance culture between friends and adolescent appearance-based rejection sensitivity.

    Science.gov (United States)

    Webb, Haley J; Zimmer-Gembeck, Melanie J; Donovan, Caroline L

    2014-06-01

    Appearance-based rejection sensitivity (appearance-RS) is the tendency to anxiously expect, readily perceive, and overreact to signs of rejection based on one's appearance, and is associated with a number of psychological and social problems (Park, 2007). This study of 380 adolescents (Mage = 13.84) examined a model linking the appearance culture between friends with appearance-RS in adolescent boys and girls, via internalisation of appearance ideals, social comparison, and body dissatisfaction. Gender differences were also tested. Consistent with expectations, appearance-focused characteristics of the friendship context were associated with heightened appearance-RS via internalization of appearance ideals, social comparison, and body dissatisfaction. The appearance-focused friend characteristics that were associated with appearance-RS included exposure to friends' appearance conversations, appearance teasing that caused distress, and perceived pressure to be attractive. Notably, associations rarely differed for boys and girls, with one exception: the association between BMI and body dissatisfaction was stronger in girls than in boys.

  20. Stability and Sensitivity Analysis of a Plant Disease Model with Continuous Cultural Control Strategy

    Directory of Open Access Journals (Sweden)

    Zhang Zhonghua

    2014-01-01

    Full Text Available In this paper, a plant disease model with continuous cultural control strategy and time delay is formulated. Then, how the time delay affects the overall disease progression and, mathematically, how the delay affects the dynamics of the model are investigated. By analyzing the transendental characteristic equation, stability conditions related to the time delay are derived for the disease-free equilibrium. Specially, when R0=1, the Jacobi matrix of the model at the disease-free equilibrium always has a simple zero eigenvalue for all τ≥0. The center manifold reduction and the normal form theory are used to discuss the stability and the steady-state bifurcations of the model near the nonhyperbolic disease-free equilibrium. Then, the sensitivity analysis of the threshold parameter R0 and the positive equilibrium E* is carried out in order to determine the relative importance of different factors responsible for disease transmission. Finally, numerical simulations are employed to support the qualitative results.

  1. Simple and sensitive method for monitoring drug-induced cell injury in cultured cells

    Energy Technology Data Exchange (ETDEWEB)

    Shirhatti, V.; Krishna, G.

    1985-06-01

    A simple, sensitive method has been developed for evaluating cell injury noninvasively in monolayer cells in culture. The cell ATP pool was radiolabeled by incubating the cells with (/sup 14/C)adenine. The uptake and incorporation of (/sup 14/C)adenine was shown to proportional to the number of cells. As determined by HPLC, about 65-70% of the incorporated /sup 14/C label was in the ATP pool, 15-20% was in the ADP pool, and the rest was in the 5'-AMP pool. When prelabeled cells were exposed to toxic drugs (acetaminophen, calcium ionophore A-23187, or daunomycin) there was a marked decrease in cell ATP with a concomitant increase in leakage of labeled nucleotides, mainly 5'-AMP and 5'IMP. The authors have shown that leakage of /sup 14/C label into the medium from the prelabeled cells may be employed for quantitation of cell injury. This new measure of toxicity was shown to correlate very well with LDH leakage from the cells, which is a well accepted measure of cell injury. The leakage of 5'-(/sup 14/C)AMP also correlated very well with the reduction of cell ATP in cardiac myocytes. This method has been used for monitoring drug-induced toxicity in liver cells, cardiac myocytes, and LB cells.

  2. A multimethod approach for cross-cultural training in an internal medicine residency program

    Directory of Open Access Journals (Sweden)

    Lisa J. Staton

    2013-05-01

    Full Text Available Background: Cultural competence training in residency is important to improve learners’ confidence in cross-cultural encounters. Recognition of cultural diversity and avoidance of cultural stereotypes are essential for health care providers. Methods: We developed a multimethod approach for cross-cultural training of Internal Medicine residents and evaluated participants’ preparedness for cultural encounters. The multimethod approach included (1 a conference series, (2 a webinar with a national expert, (3 small group sessions, (4 a multicultural social gathering, (5 a Grand Rounds presentation on cross-cultural training, and (6 an interactive, online case-based program. Results: The program had 35 participants, 28 of whom responded to the survey. Of those, 16 were white (62%, and residents comprised 71% of respondents (n=25. Following training, 89% of participants were more comfortable obtaining a social history. However, prior to the course only 27% were comfortable caring for patients who distrust the US system and 35% could identify religious beliefs and customs which impact care. Most (71% believed that the training would help them give better care for patients from different cultures, and 63% felt more comfortable negotiating a treatment plan following the course. Conclusions: Multimethod training may improve learners’ confidence and comfort with cross-cultural encounters, as well as lay the foundation for ongoing learning. Follow-up is needed to assess whether residents’ perceived comfort will translate into improved patient outcomes.

  3. Comparison of communication skills between trained and untrained students using a culturally sensitive nurse-client communication guideline in Indonesia

    NARCIS (Netherlands)

    Claramita, M.; Tuah, R.; Riskione, P.; Prabandari, Y.S.; Effendy, C.

    2016-01-01

    BACKGROUND: A communication guideline that is sensitive to the local culture is influential in the process of nursing care. The Gadjah Mada nurse-client communication guideline, the "Ready-Greet-Invite-Discuss," was meant (1) to strengthen the relationship between the nurse and the client despite of

  4. Developing a Culturally Appropriate Depression Prevention Program: Opportunities and Challenges

    Science.gov (United States)

    Cardemil, Esteban V.; Kim, Saeromi; Davidson, Tatiana; Sarmiento, Ingrid A.; Ishikawa, Rachel Zack; Sanchez, Monica; Torres, Sandra

    2010-01-01

    This paper describes the experiences of the first author and his colleagues in the development and implementation of a depression prevention program that specifically targets Latina mothers. Building on the earlier papers that highlight the underutilization of mental health services by Latinos in general, this paper will make the case that the…

  5. Healthcare technologies, quality improvement programs and hospital organizational culture in Canadian hospitals.

    Science.gov (United States)

    Tyagi, Rajesh K; Cook, Lori; Olson, John; Belohlav, James

    2013-10-13

    Healthcare technology and quality improvement programs have been identified as a means to influence healthcare costs and healthcare quality in Canada. This study seeks to identify whether the ability to implement healthcare technology by a hospital was related to usage of quality improvement programs within the hospital and whether the culture within a hospital plays a role in the adoption of quality improvement programs. A cross-sectional study of Canadian hospitals was conducted in 2010. The sample consisted of hospital administrators that were selected by provincial review boards. The questionnaire consisted of 3 sections: 20 healthcare technology items, 16 quality improvement program items and 63 culture items. Rasch model analysis revealed that a hierarchy existed among the healthcare technologies based upon the difficulty of implementation. The results also showed a significant relationship existed between the ability to implement healthcare technologies and the number of quality improvement programs adopted. In addition, culture within a hospital served a mediating role in quality improvement programs adoption. Healthcare technologies each have different levels of difficulty. As a consequence, hospitals need to understand their current level of capability before selecting a particular technology in order to assess the level of resources needed. Further the usage of quality improvement programs is related to the ability to implement technology and the culture within a hospital.

  6. Teaching methods and an outcome tool for measuring cultural sensitivity in undergraduate nursing students.

    Science.gov (United States)

    Hughes, Kathleen H; Hood, Lucy J

    2007-01-01

    A major challenge facing the nursing profession is to educate and assist nurses to develop the skills to provide culturally relevant care. This article describes one school's multicultural curriculum for baccalaureate nursing students and a tool to measure changes in behaviors and attitudes. The article presents the psychometric properties of the Cross-Cultural Evaluation Tool that yields a cross-cultural interaction score. Successful teaching strategies are presented that are substantiated by increased student cross-cultural interaction score scores.

  7. HOW THE PROGRAMCULTURAL CAPITAL OF EUROPE” INFLUENCE THE DEVELOPMENT OF TOURISM IN CITIES

    Directory of Open Access Journals (Sweden)

    Florina Dorina COZEA

    2013-06-01

    Full Text Available The programCultural Capital of Europe” started in 1985 in Athens, Greece and since then more than 45 cities from Europe have benefited of the status of Cultural Capital of Europe but only one Romanian city, Sibiu in 2007. To see the implications that this program has on tourism field and in what way it contributes to the development of this sector from the cities it will be analyzed the case of Sibiu, former Cultural Capital of Europe and Cluj Napoca that wants to have this title in the future. In the case of Sibiu several indicators will be taken into consideration. Their analysis will emphasize the relevance of this program within the tourism sector. The above mentioned indicators are: tourist’s arrivals, tourist’s check-ins, accommodation capacity. Besides these indicators there will be also considered other elements that have had an impact on this program like: type and structure of the events and the actors involved in the events' organization. In what concerns Cluj Napoca, it will be analyzed the potential of the cultural heritage that is present in the city at the present moment and in what way it can contribute to the organisation of such program.These two cities are both from Transylvania and have a similar geographical configuration, urban architecture and culture.

  8. Ethnic Identity and Parenting Stress in South Asian Families: Implications for Culturally Sensitive Counselling

    Science.gov (United States)

    Shariff, Aneesa

    2009-01-01

    The South Asian culture is one in which family obligation and loyalty, as well as self-sacrifice and obedience toward one's elders, are paramount. These values can be different from those of the more individualistically oriented Euro-Canadian dominant culture, and can prompt challenges of cultural adjustment among Canadian-born South Asian youth…

  9. Rhamnolipids elicit the same cytotoxic sensitivity between cancer cell and normal cell by reducing surface tension of culture medium.

    Science.gov (United States)

    Jiang, Lifang; Shen, Chong; Long, Xuwei; Zhang, Guoliang; Meng, Qin

    2014-12-01

    Biosurfactant rhamnolipids have been claimed to show biological activities of inhibiting the proliferation of cancer cells. In this study, the cytotoxicity of rhamnolipids was examined on four cancer cells (HepG2, Caco-2, Hela, MCF-7 cells) and two normal cells (HK-2 cell, primary hepatocyte). Interestingly, both cancer cells and normal cells exhibited similar sensitivities to the addition of rhamnolipids in culture medium, and the cytotoxicity was largely attenuated by the presence of fetal bovine serum (FBS) in culture medium. In correlation of the mono-/di-rhamnolipid cytotoxicity with the surface tension of culture medium, it was found that rhamnolipids triggered cytotoxicity whenever the surface tension of culture medium decreased below 41 mN/m irrespective of the FBS content in culture medium, cell line, or rhamnolipid congener. Similarly, each chemical surfactant (Tween-80, sodium dodecyl sulfate, and sodium dodecyl benzene sulfonate) could cause cytotoxicity on HepG2 cells whenever its addition made the surface tension under 41 mN/m in culture medium with or without the presence of FBS. It seems that rhamnolipids, like chemical surfactants, exhibited cytotoxicity by reducing the surface tension of culture medium rather than by changing its specific molecular structure, which had no selection on tumor cells. This study could offer helps to correct the misleading biological activity of rhamnolipids and to avoid the possible large wastes of time and expenses on developing the applications in antitumor drugs.

  10. The geography and human cultural resources working group of the EROS program

    Science.gov (United States)

    Gerlach, A. C.

    1972-01-01

    The functions, activities, and objectives of the Geography and Human-Cultural Resources Working Group of the EROS program are outlined. The Group's primary function is to coordinate remote sensing experiments of physical scientists and the needs of socioeconomic and culturally orientated planners, policy makers, administrators, and other user groups. Other functions of the Group include land use analysis, resource mapping, and development of an operational automatic information system receptive to land use and environmental data.

  11. The geography and human cultural resources working group of the EROS program

    Science.gov (United States)

    Gerlach, A. C.

    1972-01-01

    The functions, activities, and objectives of the Geography and Human-Cultural Resources Working Group of the EROS program are outlined. The Group's primary function is to coordinate remote sensing experiments of physical scientists and the needs of socioeconomic and culturally orientated planners, policy makers, administrators, and other user groups. Other functions of the Group include land use analysis, resource mapping, and development of an operational automatic information system receptive to land use and environmental data.

  12. Culturally-Tailored Education Programs to Address Health Literacy Deficits and Pervasive Health Disparities among Hispanics in Rural Shelbyville, Kentucky.

    Science.gov (United States)

    Ramos, Irma N; Ramos, Kenneth S; Boerner, Aisa; He, Qiang; Tavera-Garcia, Marco A

    2013-11-16

    This investigation was conducted to evaluate the impact of culturally-tailored education on health knowledge among Hispanic residents of rural, Shelbyville, KY. The program identified specific pathways to address health literacy deficits and disparities identified through a community-wide health assessment completed in 2010. A total of 43 Hispanic males who shared deficiencies in community-wide health infrastructure were enrolled in the program. The curriculum included an introductory session followed by five, subject-specific, sessions offered on a weekly basis from February to April 2011. Pre/post-test assessments showed marked improvement in knowledge base for all participants after each session, most notably related to cardiovascular disease, diabetes and metabolic syndrome. The group reconvened in January 2012 for follow-up instruction on cardiovascular disease and diabetes, as well as global assessment of knowledge retention over a nine-month period. Comparisons of pre/post testing in cardiovascular disease and diabetes, as well as global health-related knowledge showed significant gains for all parameters. Health education programs that embrace perceptions of the community of their own health, and that integrate knowledge into culturally-sensitive education, significantly improved health knowledge among Hispanic residents in rural Kentucky. Such gains may translate into sustainable improvements in health literacy and help reduce health disparities.

  13. Radiation sensitivity of poliovirus, a model for norovirus, inoculated in oyster (Crassostrea gigas) and culture broth under different conditions

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Pil-Mun [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Park, Jae Seok [Korea Food and Drug Administration, Seoul 122-704 (Korea, Republic of); Park, Jin-Gyu; Park, Jae-Nam; Han, In-Jun; Song, Beom-Seok; Choi, Jong-il; Kim, Jae-Hun; Byun, Myung-Woo [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of); Baek, Min [Atomic Energy Policy Division, Ministry of Education, Science and Technology, Gwacheon 427-715 (Korea, Republic of); Chung, Young-Jin [Department of Food and Nutrition, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Lee, Ju-Woon [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 580-185 (Korea, Republic of)], E-mail: sjwlee@kaeri.re.kr

    2009-07-15

    Poliovirus is a recognized surrogate for norovirus, pathogen in water and food, due to the structural and genetic similarity. Although radiation sensitivity of poliovirus in water or media had been reported, there has been no research in food model such as shellfish. In this study, oyster (Crassostrea gigas) was incubated in artificial seawater contaminated with poliovirus, and thus radiation sensitivity of poliovirus was determined in inoculated oyster. The effects of ionizing radiation on the sensitivity of poliovirus were also evaluated under different conditions such as pH (4-7) and salt concentration (1-15%) in culture broth, and temperature during irradiation. The D{sub 10} value of poliovirus in PBS buffer, virus culture broth and oyster was determined to 0.46, 2.84 and 2.94 kGy, respectively. The initial plaque forming unit (PFU) of poliovirus in culture broth was slightly decreased as the decrease of pH and the increase of salt concentration, but radiation sensitivity was not affected by pH and salt contents. However, radiation resistance of poliovirus was increased at frozen state. These results provide the basic information for the inactivation of pathogenic virus in foods by using irradiation.

  14. Radiation sensitivity of poliovirus, a model for norovirus, inoculated in oyster ( Crassostrea gigas) and culture broth under different conditions

    Science.gov (United States)

    Jung, Pil-Mun; Park, Jae Seok; Park, Jin-Gyu; Park, Jae-Nam; Han, In-Jun; Song, Beom-Seok; Choi, Jong-il; Kim, Jae-Hun; Byun, Myung-Woo; Baek, Min; Chung, Young-Jin; Lee, Ju-Woon

    2009-07-01

    Poliovirus is a recognized surrogate for norovirus, pathogen in water and food, due to the structural and genetic similarity. Although radiation sensitivity of poliovirus in water or media had been reported, there has been no research in food model such as shellfish. In this study, oyster ( Crassostrea gigas) was incubated in artificial seawater contaminated with poliovirus, and thus radiation sensitivity of poliovirus was determined in inoculated oyster. The effects of ionizing radiation on the sensitivity of poliovirus were also evaluated under different conditions such as pH (4-7) and salt concentration (1-15%) in culture broth, and temperature during irradiation. The D10 value of poliovirus in PBS buffer, virus culture broth and oyster was determined to 0.46, 2.84 and 2.94 kGy, respectively. The initial plaque forming unit (PFU) of poliovirus in culture broth was slightly decreased as the decrease of pH and the increase of salt concentration, but radiation sensitivity was not affected by pH and salt contents. However, radiation resistance of poliovirus was increased at frozen state. These results provide the basic information for the inactivation of pathogenic virus in foods by using irradiation.

  15. [The preparation phosprenyl suppresses diarrhea and cattle infectious rhinotracheitis virus multiplication in sensitive cell cultures].

    Science.gov (United States)

    Ozherelkov, S V; Belousova, R V; Danilov, L L; Deeva, A V; Mal'tsev, S D; Narovlianskiĭ, A N; Sanin, A V; Pronin, A V

    2001-01-01

    Fosprenil suppressed the multiplication of cattle diarrhea virus in calf coronary vessel cell culture. Added to the culture of infected cells in a dose of 200 mg, the drug decreased the virus titer 30-fold in comparison with infected control cultures. Antiviral activity of fosprenil towards infective rhinotracheitis virus multiplication was still higher: in a dose of 100 mg it decreased the virus titer in fetal calf lung culture 100-fold in comparison with the control. Moreover, the cytopathogenic effects of the viruses in infected cultures were 24-48 h delayed under the effect of fosprenil in comparison with infected control cultures. These results recommend fosprenil for the treatment of cattle viral diseases.

  16. Anxiety Sensitivity Amelioration Training (ASAT): a longitudinal primary prevention program targeting cognitive vulnerability.

    Science.gov (United States)

    Schmidt, Norman B; Eggleston, A Meade; Woolaway-Bickel, Kelly; Fitzpatrick, Kathleen Kara; Vasey, Michael W; Richey, J Anthony

    2007-01-01

    Fear of arousal symptoms, often referred to as anxiety sensitivity (AS) appears to be associated with risk for anxiety pathology and other Axis I conditions. Findings from a longitudinal prevention program targeting AS are reported. Participants (n=404) scoring high on the Anxiety Sensitivity Index (ASI) were randomly assigned to receive a brief intervention designed to reduce AS (Anxiety Sensitivity Amelioration Training (ASAT)) or a control condition. Participants were followed for up to 24 months. Findings indicate that ASAT produced greater reductions in ASI levels compared with the control condition. Moreover, reductions were specific to anxiety sensitivity relative to related cognitive risk factors for anxiety. ASAT also produced decreased subjective fear responding to a 20% CO(2) challenge delivered postintervention. Data from the follow-up period show a lower incidence of Axis I diagnoses in the treated condition though the overall group difference was not statistically different at all follow-up intervals. Overall, findings are promising for the preventative efficacy of a brief, computer-based intervention designed to decrease anxiety sensitivity.

  17. Initiatives to Improve Feedback Culture in the Final Year of a Veterinary Program

    OpenAIRE

    2014-01-01

    Despite the recognized importance of feedback in education, student satisfaction with the feedback process in medical and veterinary programs is often disappointing. We undertook various initiatives to try to improve the feedback culture in the final clinical year of the veterinary program at the University of Bristol, focusing on formative verbal feedback. The initiatives included E-mailed guidelines to staff and students, a faculty development workshop, and a reflective portfolio task for s...

  18. LGBTQ Youth and Young Adult Perspectives on a Culturally Tailored Group Smoking Cessation Program.

    Science.gov (United States)

    Baskerville, Neill Bruce; Shuh, Alanna; Wong-Francq, Katy; Dash, Darly; Abramowicz, Aneta

    2017-01-25

    The prevalence of smoking among LGBTQ youth and young adults (YYAs) is much higher than that of non-LGBTQ young people. The current study explored LGBTQ YYA perceptions of a culturally tailored group smoking cessation counselling program, along with how the intervention could be improved. We conducted focus groups (n = 24) with 204 LGBTQ YYAs in Toronto and Ottawa, Canada. Open-ended questions focused on their feelings, likes and dislikes, concerns and additional ideas for a culturally tailored group cessation counselling intervention. Focus group transcripts were coded thematically and analyzed. Overall, YYAs were ambivalent towards the concept of a culturally tailored, group cessation counselling program. Although several participants were attracted to the LGBTQ friendly and social benefits of such a program (eg, good support system), many also had concerns. Particularly, the possibility that other group members might trigger them to smoke was a frequently stated issue. Focus group members also noted lack of motivation to attend the group, and that the group program may be inaccessible depending on where and when the program was offered. Several suggestions were made as to how to ameliorate the expressed issues related to inaccessibility or lack of attractiveness. This study is among the first to gain the perspectives of LGBTQ YYAs on culturally tailored group cessation strategies in Canada. We identified components of group cessation programs that are both favored and not favored among LGBTQ YYAs, as well as suggestions as to how to make group cessation programs more appealing. This study is particularly relevant as smoking cessation programs are one of the most commonly offered and published cessation interventions for the LGBTQ community, yet little is understood in terms of preferences of LGBTQ YYA smokers. Given the disparity in the prevalence of smoking among LGBTQ young people compared to their non-LGBTQ peers, research on effective intervention strategies

  19. Application of ImageJ program to the enumeration of Orientia tsutsugamushi organisms cultured in vitro

    OpenAIRE

    2012-01-01

    The ImageJ program was applied to the enumeration of Orientia tsutsugamushi organisms in cell culture using indirect immunofluorescence assay (IFA). The highest correlation (r = 0.984) was observed between manual counting methods and the ImageJ program (MaxEntropy threshold algorithm). This software-based methodology is cheaper, more standardised and better reproducible than a manual-based approach.

  20. Evaluation of a cross-cultural training program for Pakistani educators: Lessons learned and implications for program planning.

    Science.gov (United States)

    Mazur, Rebecca; Woodland, Rebecca H

    2017-02-20

    In this paper, we share the results of a summative evaluation of PEILI, a US-based adult professional development/training program for secondary school Pakistani teachers. The evaluation was guided by the theories of cultural competence (American Psychological Association, 2003; Bamberger, 1999; Wadsworth, 2001) and established frameworks for the evaluation of professional development/training and instructional design (Bennett, 1975; Guskey, 2002; King, 2014; Kirkpatrick, 1967). The explicit and implicit stakeholder assumptions about the connections between program resources, activities, outputs, and outcomes are described. Participant knowledge and skills were measured via scores on a pre/posttest of professional knowledge, and a standards-based performance assessment rubric. In addition to measuring short-term program outcomes, we also sought to incorporate theory-driven thinking into the evaluation design. Hence, we examined participant self-efficacy and access to social capital, two evidenced-based determinants or "levers" that theoretically explain the transformative space between an intervention and its outcomes (Chen, 2012). Data about program determinants were collected and analyzed through a pre/posttest of self-efficacy and social network analysis. Key evaluation findings include participant acquisition of new instructional skills, increased self-efficacy, and the formation of a nascent professional support network. Lessons learned and implications for the design and evaluation of cross-cultural teacher professional development programs are discussed.

  1. Randomised Response Technique-An Innovative Method To Measure Culturally Sensitive Variables : Results From A Pilot Study

    Directory of Open Access Journals (Sweden)

    Soudarssanane M. B

    2003-01-01

    Full Text Available Research questions: What is the advantage of Randomized Response Technique (RRT over the conventional Direct Interview (DI and Anonymous Questionnaire (AQ in the assessment of culturally sensitive variables? Objectives: To compare the efficacy of the three methods, namely RRT, DI and AQ in the measurement of prevalence of Pre/Extra marital sex. Study design: Cross sectional study, using the three methods. Setting: A pilot study in a given community in Pondicherry. Statistical analysis: Probability equations. Results: The prevalence of pre/extra marital sex in the study population by the DI, AQ and RRT methods were 0%, 6% and 10% respectively in this pilot study. Conclusion: RRT improves validity of measurement of culturally sensitive variables both by ensuring a high participation in the study and by enabling a true response by assuring full confidentiality of information.

  2. Korean Student's Online Learning Preferences and Issues: Cultural Sensitivity for Western Course Designers

    Science.gov (United States)

    Washburn, Earlene

    2012-01-01

    Scope and Method of Study: While online courses offer educational solutions, they are not academically suited for everyone. International students find distractions in online courses constructed with American philosophy, epistemology, values, and cultures as compared to experiences in their home country. Learner's culture, value system, learning…

  3. Korean Student's Online Learning Preferences and Issues: Cultural Sensitivity for Western Course Designers

    Science.gov (United States)

    Washburn, Earlene

    2012-01-01

    Scope and Method of Study: While online courses offer educational solutions, they are not academically suited for everyone. International students find distractions in online courses constructed with American philosophy, epistemology, values, and cultures as compared to experiences in their home country. Learner's culture, value system, learning…

  4. The Risks Of Using Workplace Wellness Programs To Foster A Culture Of Health.

    Science.gov (United States)

    Madison, Kristin M

    2016-11-01

    In many respects, employers are well positioned to take a leading role in helping create a culture of health. Employers have access to many programs that could be beneficial to their employees' health. The potential for financial gains related to health improvement may motivate employers to offer these programs, and if the gains are realized, they may help finance the programs. At the same time, employers' involvement in such programs may create substantial risks. Enthusiasm about the financial and health gains that wellness programs might yield coexists with concerns about health costs shouldered by employees, the possibility of employment discrimination, and the potential for employers' invasion of employees' privacy. A fragmented regulatory regime, including a recently issued final rule under the Americans with Disabilities Act, has been created to address these concerns. Whether the regime strikes the right balance between wellness program benefits and risks remains to be determined.

  5. Motivating Young Native American Students to Pursue STEM Learning Through a Culturally Relevant Science Program

    Science.gov (United States)

    Stevens, Sally; Andrade, Rosi; Page, Melissa

    2016-12-01

    Data indicate that females and ethnic/race minority groups are underrepresented in the science and engineering workforce calling for innovative strategies to engage and retain them in science education and careers. This study reports on the development, delivery, and outcomes of a culturally driven science, technology, engineering, mathematics (STEM) program, iSTEM, aimed at increasing engagement in STEM learning among Native American 3rd-8th grade students. A culturally relevant theoretical framework, Funds of Knowledge, informs the iSTEM program, a program based on the contention that the synergistic effect of a hybrid program combining two strategic approaches (1) in-school mentoring and (2) out-of-school informal science education experiences would foster engagement and interest in STEM learning. Students are paired with one of three types of mentors: Native American community members, university students, and STEM professionals. The iSTEM program is theme based with all program activities specifically relevant to Native people living in southern Arizona. Student mentees and mentors complete interactive flash STEM activities at lunch hour and attend approximately six field trips per year. Data from the iSTEM program indicate that the program has been successful in engaging Native American students in iSTEM as well as increasing their interest in STEM and their science beliefs.

  6. Understanding the Geographies of Transport and Cultural Heritage: Comparing Two Urban Development Programs in Oslo

    Directory of Open Access Journals (Sweden)

    Anders Tønnesen

    2014-05-01

    Full Text Available This paper elaborates on how policies and strategies for sustainable urban development can be understood and shows how development programs can be strategically important and flexible tools in the creation of the modern city. We examine two typical contemporary cases for urban development, inner city/waterfront and modernistic suburbs, using the two areas of transport and cultural heritage as prisms to explore divergences or convergences between the two programs, and ask: How come two urban development programs within the same city turn out so differently? By comparing these programs, urban development trends relating to entrepreneurialism are highlighted. There are clear differences between the two programs under study, and the paper tries to grasp their internal logic in order to shed light on their strengths and weaknesses. While the city center program has much to do with realizing the commercial potential of the area and strengthening sustainable transport through large-scale changes in infrastructure, such means seem to be outside the scope of the suburban program. Meanwhile, cultural heritage is interwoven with entrepreneurial projection-strategies in the city center, whereas heritage sites and projects are used more as a means for social cohesion in the suburb. The paper concludes that the programs vary in the two policy fields in accordance with the institutionalized and anticipated potential of the urban areas in question.

  7. Motivating Young Native American Students to Pursue STEM Learning Through a Culturally Relevant Science Program

    Science.gov (United States)

    Stevens, Sally; Andrade, Rosi; Page, Melissa

    2016-06-01

    Data indicate that females and ethnic/race minority groups are underrepresented in the science and engineering workforce calling for innovative strategies to engage and retain them in science education and careers. This study reports on the development, delivery, and outcomes of a culturally driven science, technology, engineering, mathematics (STEM) program, iSTEM, aimed at increasing engagement in STEM learning among Native American 3rd-8th grade students. A culturally relevant theoretical framework, Funds of Knowledge, informs the iSTEM program, a program based on the contention that the synergistic effect of a hybrid program combining two strategic approaches (1) in-school mentoring and (2) out-of-school informal science education experiences would foster engagement and interest in STEM learning. Students are paired with one of three types of mentors: Native American community members, university students, and STEM professionals. The iSTEM program is theme based with all program activities specifically relevant to Native people living in southern Arizona. Student mentees and mentors complete interactive flash STEM activities at lunch hour and attend approximately six field trips per year. Data from the iSTEM program indicate that the program has been successful in engaging Native American students in iSTEM as well as increasing their interest in STEM and their science beliefs.

  8. A Study of the Inter-Cultural Sensitivity among the Faculty of English Language Centre of Jazan University, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Saeed Ahmad

    2016-11-01

    Full Text Available study explored intercultural sensitivity of 103 faculty members of the English Language Centre (ELC of Jazan University, Saudi Arabia. A quantitative and non-experimental design was adopted for this study in which intercultural sensitivity of the English language teachers was evaluated on five demographic variables (e.g. gender, education, religion, total teaching experience, and experience of teaching in intercultural context. The results revealed that the international faculty of ELC abreast the basic canons of Intercultural adjustments. This suggests that the teachers are not only familiar with different cultural patterns (like beliefs, values and communication styles they are willing to minimize these differences and adopt universal set of values for effective educational practices. The results indicate the participants’ higher level of empathy, respect for others’ culture, tolerance on differences and high willingness to integrate with other cultures. The data reveals no statistically significant difference between the two groups in three variables, i.e. gender (Male & Female, qualification (Masters' & Ph.D and religion (Muslims & Non-Muslims. However, there was found a statistically significant difference in the two groups (Less than ten years & More than ten years in two variables, i.e. total teaching experience and teaching experience in intercultural context. Keywords: Adaptability, English Teaching, Intercultural Sensitivity

  9. The Outdoor World: An Outdoor Science and Culture Program for Seneca Indian Children.

    Science.gov (United States)

    Dobey, Daniel C.

    1994-01-01

    Describes an outdoor summer science program for Seneca Indian children in grades 5-7 that featured weekly outdoor topics integrating science, traditional Native American/Seneca culture, and skills in reading and language arts. Daily activities included field trips, community guests, storytelling, and individual and group projects. (LP)

  10. The Science-Humanities Program (NEXA) at San Francisco State University: The 'Two Cultures' Reconsidered.

    Science.gov (United States)

    Gregory, Michael S.

    1980-01-01

    The origin of the NEXA Program at San Francisco State University is described. A historical summary is offered of the 'two-cultures' dilemma, whose origins are traced to the seventeenth century and whose consequences for the nineteenth and twentieth century experience are examined. (Author/MLW)

  11. Culturally Responsive Pyramid Model Practices: Program-Wide Positive Behavior Support for Young Children

    Science.gov (United States)

    Allen, Rosemarie; Steed, Elizabeth A.

    2016-01-01

    This conceptual article reviews current research on racial disparities in disciplinary practices in early childhood education and work to address these issues within a positive behavior support (PBS) framework. Building largely on the Pyramid Model, recommendations and a culturally responsive approach are suggested for use within a program-wide…

  12. Applying Medical Anthropology: Developing Diabetes Education and Prevention Programs in American Indian Cultures.

    Science.gov (United States)

    Olson, Brooke

    1999-01-01

    Medical anthropology provides a broader contextual framework for understanding complex causal factors associated with diabetes among American Indians and how to minimize these factors in education/treatment programs. Discusses historical, epidemiological, and genetic considerations in American Indian diabetes; cultural factors related to foods,…

  13. AN EVALUATION OF A PRESCHOOL TRAINING PROGRAM FOR CULTURALLY DEPRIVED CHILDREN. FINAL REPORT.

    Science.gov (United States)

    TAMMINEN, ARMAS W.; AND OTHERS

    TO FIND OUT IF CULTURALLY DEPRIVED CHILDREN SHOW CHANGE IN ACADEMIC READINESS AS A RESULT OF SPECIAL PRESCHOOL PROGRAMS, 3 GROUPS OF CHILDREN (14 TO 17 IN EACH) IN 3 DULUTH SCHOOL AREAS WERE PRE- AND POSTTESTED WITH THE STANFORD-BINET AND SRA PRIMARY MENTAL ABILITIES TESTS. A CONTROL GROUP OF 30 CHILDREN FROM THE SAME 3 SCHOOL AREAS WERE GIVEN THE…

  14. Japanese Language and Culture: 9-Year Program Classroom Assessment Materials, Grade 4

    Science.gov (United States)

    Alberta Education, 2008

    2008-01-01

    This document is designed to provide assessment materials for specific Grade 4 outcomes in the Japanese Language and Culture Nine-year Program, Grades 4-5-6. The assessment materials are designed for the beginner level in the context of teaching for communicative competence. Grade 4 learning outcomes from the Japanese Language and Culture…

  15. The Cultural Genogram: experiences from within a marriage and family therapy training program.

    Science.gov (United States)

    Keiley, Margaret K; Dolbin, Megan; Hill, Jennifer; Karuppaswamy, Nithyakala; Liu, Ting; Natrajan, Rajeswari; Poulsen, Shruti; Robbins, Natashia; Robinson, Pamela

    2002-04-01

    The purpose of this article is to illustrate and demonstrate the use of the Cultural Genogram (CG) in a graduate-level course in gender and culture for family therapists-in-training at a large Midwestern university's accredited program in family therapy. Although the importance of the CG as a training tool is delineated by Hardy and Laszloffy, very little information exists about the actual implementation and usefulness of this tool within a training program for family therapists. In this article, we present a qualitative research study of the lived experiences of a class of women from diverse cultures as they constructed and presented their CGs. We discuss the basic curriculum and structure of the course in which the CG was used, the process the class members developed to create and present their CGs, the effects of presenting the CGs, and a set of recommendations and ideas for further exploration.

  16. Assessing Exporting Culture in Colombian SMEs: A Look at the ExportPromotion Program (EPP)

    OpenAIRE

    Sierra González, Jaime Humberto

    2009-01-01

    This paper makes an assessment of the Colombian Export Promotion Program. The process and the results of such a program are considered in the light of the literature on international strategy and exporting culture in developed and developing countries. Literature findings on EPAs and EPPs around the world are complemented by information from two surveys, one applied to a set of 56 firms that took part in the EPP (2002-2004) and the other addressed at a group of consultants hired by program op...

  17. Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet

    Directory of Open Access Journals (Sweden)

    Yi Luan

    2017-07-01

    Full Text Available Hemin is a breakdown product of hemoglobin. It has been reported that the injection of hemin improves lipid metabolism and insulin sensitivity in various genetic models. However, the effect of hemin supplementation in food on lipid metabolism and insulin sensitivity is still unclear, and whether hemin directly affects cellular insulin sensitivity is yet to be elucidated. Here we show that hemin enhances insulin-induced phosphorylation of insulin receptors, Akt, Gsk3β, FoxO1 and cytoplasmic translocation of FoxO1 in cultured primary hepatocytes under insulin-resistant conditions. Furthermore, hemin diminishes the accumulation of triglyceride and increases in free fatty acid content in primary hepatocytes induced by palmitate. Oral administration of hemin decreases body weight, energy intake, blood glucose and triglyceride levels, and improves insulin and glucose tolerance as well as hepatic insulin signaling and hepatic steatosis in male mice fed a high-fat diet. In addition, hemin treatment decreases the mRNA and protein levels of some hepatic genes involved in lipogenic regulation, fatty acid synthesis and storage, and increases the mRNA level and enzyme activity of CPT1 involved in fatty acid oxidation. These data demonstrate that hemin can improve lipid metabolism and insulin sensitivity in both cultured hepatocytes and mice fed a high-fat diet, and show the potential beneficial effects of hemin from food on lipid and glucose metabolism.

  18. The role of national culture in advertising's sensitivity to business cycles : An investigation across continents

    NARCIS (Netherlands)

    Deleersnyder, B.; DeKimpe, M.; Steenkamp, J.E.M.; Leeflang, P.S.H.

    2009-01-01

    The authors conduct a systematic investigation into the cyclical sensitivity of advertising expenditures in 37 countries, covering four key media: magazines, newspapers, radio, and television. They show that advertising is considerably more sensitive to business-cycle fluctuations than the economy a

  19. Shear sensitivity of animal cells from a culture-medium perspective.

    NARCIS (Netherlands)

    Pol, van der L.; Tramper, J.

    1998-01-01

    Recently, several groups have published data on the shear sensitivity of suspended animal cells and the protective effect of certain polymers. These findings did not, at the time, seem to have great practical application because shear sensitivity did not cause great problems for large-scale applicat

  20. The role of national culture in advertising's sensitivity to business cycles : An investigation across continents

    NARCIS (Netherlands)

    Deleersnyder, B.; DeKimpe, M.; Steenkamp, J.E.M.; Leeflang, P.S.H.

    2009-01-01

    The authors conduct a systematic investigation into the cyclical sensitivity of advertising expenditures in 37 countries, covering four key media: magazines, newspapers, radio, and television. They show that advertising is considerably more sensitive to business-cycle fluctuations than the economy a

  1. Microsystem with integrated capillary leak to mass spectrometer for high sensitivity temperature programmed desorption

    DEFF Research Database (Denmark)

    Quaade, Ulrich; Jensen, Søren; Hansen, Ole

    2004-01-01

    Temperature programmed desorption (TPD) is a method for obtaining information about quantities and binding properties of adsorbed species on a surface. A microfabricated flow system for TPD with an integrated capillary leak to a mass spectrometer is presented. The use of an integrated capillary l.......5 cm2 of platinum foil gives a clear desorption peak. By using the microfabricated flow system, TPD experiments can be performed in a carrier gas with a sensitivity approaching that of TPD experiments in vacuum. ©2004 American Institute of Physics...... leak minimizes dead volumes in the system, resulting in increased sensitivity and reduced response time. These properties make the system ideal for TPD experiments in a carrier gas. With CO desorbing from platinum as model system, it is shown that CO desorbing in 105 Pa of argon from as little as 0...

  2. Sensitivity-Informed De Novo Programming for Many-Objective Water Portfolio Planning Under Uncertainty

    Science.gov (United States)

    Kasprzyk, J. R.; Reed, P. M.; Kirsch, B. R.; Characklis, G. W.

    2009-12-01

    Risk-based water supply management presents severe cognitive, computational, and social challenges to planning in a changing world. Decision aiding frameworks must confront the cognitive biases implicit to risk, the severe uncertainties associated with long term planning horizons, and the consequent ambiguities that shape how we define and solve water resources planning and management problems. This paper proposes and demonstrates a new interactive framework for sensitivity informed de novo programming. The theoretical focus of our many-objective de novo programming is to promote learning and evolving problem formulations to enhance risk-based decision making. We have demonstrated our proposed de novo programming framework using a case study for a single city’s water supply in the Lower Rio Grande Valley (LRGV) in Texas. Key decisions in this case study include the purchase of permanent rights to reservoir inflows and anticipatory thresholds for acquiring transfers of water through optioning and spot leases. A 10-year Monte Carlo simulation driven by historical data is used to provide performance metrics for the supply portfolios. The three major components of our methodology include Sobol globoal sensitivity analysis, many-objective evolutionary optimization and interactive tradeoff visualization. The interplay between these components allows us to evaluate alternative design metrics, their decision variable controls and the consequent system vulnerabilities. Our LRGV case study measures water supply portfolios’ efficiency, reliability, and utilization of transfers in the water supply market. The sensitivity analysis is used interactively over interannual, annual, and monthly time scales to indicate how the problem controls change as a function of the timescale of interest. These results have been used then to improve our exploration and understanding of LRGV costs, vulnerabilities, and the water portfolios’ critical reliability constraints. These results

  3. Outcomes of a type 2 diabetes education program adapted to the cultural contexts of Saudi women

    Science.gov (United States)

    Al-Bannay, Hana R.; Jongbloed, Lyn E.; Jarus, Tal; Alabdulwahab, Sami S.; Khoja, Tawfik A.; Dean, Elizabeth

    2015-01-01

    Objective: To explore the outcomes of a pilot intervention of a type 2 diabetes (T2D) education program, based on international standards, and adapted to the cultural and religious contexts of Saudi women. Methods: This study is an experiment of a pilot intervention carried out between August 2011 and January 2012 at the primary health clinics in Dammam. Women at risk of or diagnosed with T2D (N=35 including dropouts) were assigned to one of 2 groups; an intervention group participated in a pilot intervention of T2D education program, based on international standards and tailored to their cultural and religious contexts; and a usual care group received the usual care for diabetes in Saudi Arabia. Outcomes included blood glucose, body composition, 6-minute walk distance, life satisfaction, quality of life, and diabetes knowledge. The intervention group participated in a focus group of their program experience. Data analysis was based on mixed methods. Results: Based on 95% confidence interval comparisons, improvements were noted in blood sugar, 6-minute walk distance, quality of life, and diabetes knowledge in participants of the intervention group. They also reported improvements in lifestyle-related health behaviors after the education program. Conclusion: Saudi women may benefit from a T2D education program based on international standards and adapted to their cultural and religious contexts. PMID:26108595

  4. Cuidate: implementation of a culturally based sexual risk reduction program for Hispanic adolescents.

    Science.gov (United States)

    Feutz, Kristi; Andresen, Pamela

    2013-01-01

    Birth rates for adolescents have been declining in the United States since 1991 for all races. However, the rate for Hispanic teens still remains significantly higher than those for White teens. The Centers for Disease Control and Prevention (CDC) recommends that community-based organizations implement evidence-based programs to address the risky sexual behaviors of adolescents. Cuidate is an evidence-based sexual risk reduction program designed specifically for Hispanic adolescents ages 13-18 years. The program uses Hispanic cultural beliefs to influence the use of abstinence and condoms as culturally accepted practices. The purpose of this article is to describe the implementation of Cuidate at a federally funded community health center to reduce the sexual risk behaviors of the adolescent Hispanic population it serves.

  5. Building relationships and facilitating immigrant community integration: An evaluation of a Cultural Navigator Program.

    Science.gov (United States)

    Thomas, Rebecca L; Chiarelli-Helminiak, Christina M; Ferraj, Brunilda; Barrette, Kyle

    2016-04-01

    Despite the long history of immigration in the United States, communities around the country struggle to integrate newcomers into the economic, cultural, and political spheres of society. Utilizing results from the program evaluation of one public library's Cultural Navigator Program, the authors illustrate how communities and public institutions can promote integration and relationship-building between newly arrived immigrants and long-time residents. Existing social networks within receiving communities, conceptualized in this article as social capital, were leveraged to build capacity among newly arrived immigrants and foster inclusivity and integration at the community level. As a place of intervention, public libraries are suggested as a safe and shared space where community integration can be fostered. Insights derived from the evaluation inform a discussion on engaging approaches to immigrant integration. Lessons learned and recommendations for program evaluators and administrators are provided.

  6. The Development of a Cultural-Based Educational Program to Enhance Breast Self-Examination (BSE Self-Efficacy

    Directory of Open Access Journals (Sweden)

    Juanita Juanita

    2012-08-01

    Full Text Available Purpose: To develop the educational program which is appropriate with Islamic culture in order to enhance BSE self-efficacy of nursing students and thus promote BSE practice. Method: This study is a development research study which is consisting of three phases including: 1 reviewing several existing BSE educational programs; 2 program design based on SCT and Islamic culture; and 3 program validation by three experts. Result: Based on previous studies, the most appropriate theory to enhance self-efficacy was Social Cognitive Theory (SCT because this theory provides several strategies to increase the self-efficacy. Further, the program that used Islamic culture was more appropriate to increase BSE practice among Muslim women. As a result, the newly developed program was developed used SCT and Islamic culture. This program was comprised of four sessions including: 1 exploring Islamic mandate on prevention and individual responsibility in health promotion, and culture-related beliefs toward BSE, 2 health education by conducting lecturing session and watching a video about BSE procedures, 3 BSE training activities including BSE demonstration and return demonstration, 4 follow-up by conducting a meeting. Conclusion: The cultural-based educational program for enhancing BSE self-efficacy and promoting BSE is a program using multifaceted methods. It designed based on a review of the literature from previous studies and were supported by research findings on experimental studies in other population. Keywords: Cultural, Educational program development, Breast self-examination, Self-efficacy.

  7. A program for generating randomized simple and context-sensitive sequences.

    Science.gov (United States)

    Remillard, Gilbert

    2008-05-01

    This article introduces Sequence Generation 2008 (SeqGen2008), a Windows-based sequence generator. SeqGen2008 can generate simple sequences satisfying user-defined event probabilities or frequencies. The program can also generate context-sensitive sequences satisfying user-defined transition matrices that specify the probabilities or frequencies with which distinct events are to follow specific contexts. An analysis of the properties and behavior of the algorithms employed by SeqGen2008 reveals that the algorithms are unbiased in their generation of sequences.

  8. Comparison of communication skills between trained and untrained students using a culturally sensitive nurse-client communication guideline in Indonesia.

    Science.gov (United States)

    Claramita, Mora; Tuah, Rodianson; Riskione, Patricia; Prabandari, Yayi Suryo; Effendy, Christantie

    2016-01-01

    A communication guideline that is sensitive to the local culture is influential in the process of nursing care. The Gadjah Mada nurse-client communication guideline, the "Ready-Greet-Invite-Discuss," was meant (1) to strengthen the relationship between the nurse and the client despite of socio-culturally hierarchical gap between health providers and clients in Indonesian context, (2) to provide attention to the unspoken concerns especially in the context of indirect communication which mostly using non-verbal signs and politeness etiquettes, and (3) to initiate dialog in the society which hold a more community-oriented decision making. Our aim is to compare the communication skills of nursing students who had and had not received a training using a culture-sensitive Gadjah Mada nurse-client communication guideline. This was a quasi experimental randomized control study to the fifth semester students of a nursing school at Yogyakarta, Indonesia. The intervention group was trained by the Gadjah Mada nurse-client communication guideline. Both intervention and the control group had learned general nurse-client communication guidelines. The training was 4h with role-plays, supportive information and feedback sessions. An objective-structured clinical examination (OSCE) was conducted 1week after the training, in seven stations, with seven simulated clients. Observers judged the communication skills of the students using a checklist of 5-point Likert scale, whereas simulated clients judged their satisfaction using 4-point Likert scale represented in colorful ribbons. There were significant mean differences in each domain of communication guideline observed between the trained and the control groups as judged by the teachers (p≤0.05) and simulated clients. Training using a culture-sensitive communication skills guideline could improve the communication skills of the nursing students and may increase satisfaction of the clients. Copyright © 2015 Elsevier Ltd. All rights

  9. Sensitivity of Scenedesmus obliquus and Microcystis aeruginosa to atrazine: effects of acclimation and mixed cultures, and their removal ability.

    Science.gov (United States)

    Chalifour, Annie; LeBlanc, André; Sleno, Lekha; Juneau, Philippe

    2016-12-01

    Atrazine is an herbicide frequently detected in watercourses that can affect the phytoplankton community, thus impacting the whole food chain. This study aims, firstly, to measure the sensitivity of monocultures of the green alga Scenedemus obliquus and toxic and non-toxic strains of the cyanobacteria Microcystis aeruginosa before, during and after a 30-day acclimation period to 0.1 µM of atrazine. Secondly, the sensitivity of S. obliquus and M. aeruginosa to atrazine in mixed cultures was evaluated. Finally, the ability of these strains to remove atrazine from the media was measured. We demonstrated that both strains of M. aeruginosa had higher growth rate-based EC50 values than S. obliquus when exposed to atrazine, even though their photosynthesis-based EC50 values were lower. After being exposed to 0.1 µM of atrazine for 1 month, only the photosynthesis-based EC50 of S. obliquus increased significantly. In mixed cultures, the growth rate of the non-toxic strain of M. aeruginosa was higher than S. obliquus at high concentrations of atrazine, resulting in a ratio of M. aeruginosa to total cell count of 0.6. This lower sensitivity might be related to the higher growth rate of cyanobacteria at low light intensity. Finally, a negligible fraction of atrazine was removed from the culture media by S. obliquus or M. aeruginosa over 6 days. These results bring new insights on the acclimation of some phytoplankton species to atrazine and its effect on the competition between S. obliquus and M. aeruginosa in mixed cultures.

  10. The Impact of a School-Based Cultural Awareness Program on Students Ethnic Identity and Self-Esteem

    Science.gov (United States)

    Braswell, Charley Alexandria

    2011-01-01

    The purpose of this quantitative study was to examine the influences of a school-based cultural awareness program on ethnic identity and self-esteem in fifth grade early adolescents. The development and implementation of a school-based cultural awareness program was intended to offer students a basic foundation for the development and/or…

  11. Building a Unit-Level Mentored Program to Sustain a Culture of Inquiry for Evidence-Based Practice

    Science.gov (United States)

    2015-03-24

    experiencing significant change . It also demonstrates that a unit-level mentored EBP program is sustainable despite changes in organizational structure...culture, readiness, beliefs, and implementation. 15. SUBJECT TERMS Evidence-based practice, culture, mentor, organizational change 16. SECURITY...Medical Command; her areas of interest include staffing, acuity, nursing workload, change management, organizational culture and empowering junior

  12. 25 CFR 1000.128 - Is there a contracting preference for programs of special geographic, historical, or cultural...

    Science.gov (United States)

    2010-04-01

    ... geographic, historical, or cultural significance? 1000.128 Section 1000.128 Indians OFFICE OF THE ASSISTANT... special geographic, historical, or cultural significance? Yes, if there is a special geographic, historical, or cultural significance to the program or activity administered by the bureau, the law...

  13. The Cultural Dependence of the Ethical Sensitivity Scale Questionnaire: The Case of Iranian Kurdish Teachers

    Directory of Open Access Journals (Sweden)

    Khalil Gholami

    2012-01-01

    Full Text Available A good theory-based tool for measuring ethical sensitivity, which is usable in different contexts, is scarce. In this study, we examined the Ethical Sensitivity Scale Questionnaire (ESSQ in line with its seven-dimension structure. The scale was presented to a sample of 556 Iranian Kurdish teachers in primary, middle, and high schools. A confirmatory factor analysis was conducted to scrutinize the original factor structure of the ESSQ. The results confirmed that the ESSQ supports a reasonable model fit to study the seven dimensions of ethical sensitivity as it was developed in the original study. However, some modifications were conducted to free high error covariance between four pairs of items in the scale. This modification increased the fit indices and thus resulted in a good model fit. In addition to examining the satiability of the ESSQ, a further analysis showed that the level of ethical sensitivity in the targeted sample was high.

  14. CULTURE AND SENSITIVITY OF BACTERIAL GROWTH FROM EXOTIC COWS SUFFERING FROM ENDOMETRITIS UNDER PAKISTANI CONDITIONS

    Directory of Open Access Journals (Sweden)

    Idrees Ali Zahid

    2004-04-01

    Full Text Available Bacteriology of endometritis and in vitro antibiotic sensitivity of the isolates in Holstein Friesian and Jersey cows maintained at Research Institute for Physiology of Animal Reproduction, Bhunikey, District Kasur were carried out. Out of 100 samples, 89 contained different strains of bacteria and 11 were found bacteriologically sterile. Different species of bacteria isolated from these samples were, Bacillus subtilis (08.99%, Corynebacterium pyogenes (19.10%, Escherichia coli (29.21%, Neisseria meningitides (03.37%, Staphylococcus aureus (23.60%, Streptococcus pneumonia (03.37% and Streptococcus pyogenes (12.36%. The in vitro antibiotic sensitivity test indicated that the highest number of isolates (92% were sensitive to neomycin, followed by doxycyline (89%. Clindramycin showed the lowest results in terms of in vitro antibiotic sensitivity (51%.

  15. Helper, Guard or Mediator? Teachers' Space for Action in "The Cultural Rucksack," a Norwegian National Program for Arts and Culture in Schools

    Science.gov (United States)

    Christophersen, Catharina

    2013-01-01

    Arts encounters in schools are often portrayed as encounters between art/artists and children. However, in such encounters, teachers are most often involved. The study presented discusses teachers' experiences with and space for action within The Cultural Rucksack; a national program for arts and culture in Norwegian schools. Observations and…

  16. Bioimpedance monitoring of 3D cell culturing-Complementary electrode configurations for enhanced spatial sensitivity

    DEFF Research Database (Denmark)

    Canali, Chiara; Heiskanen, Arto; Muhammad, Haseena Bashir

    2015-01-01

    configurations. By switching between the different combinations of electrode couples, it was possible to generate a multiplexing-like approach, which allowed for collecting spatially distributed information within the 3D space. Computational finite element (FE) analysis and electrochemical impedance......A bioimpedance platform is presented as a promising tool for non-invasive real-time monitoring of the entire process of three-dimensional (3D) cell culturing in a hydrogel scaffold. In this study, the dynamics involved in the whole process of 3D cell culturing, starting from polymerisation...... of a bare 3D gelatin scaffold, to human mesenchymal stem cell (MSC) encapsulation and proliferation, was monitored over time. The platform consists of a large rectangular culture chamber with four embedded vertical gold plate electrodes that were exploited in two- and three terminal (2T and 3T) measurement...

  17. Cultural Variations in the Effect of Interview Privacy and the Need for Social Conformity on Reporting Sensitive Information

    Directory of Open Access Journals (Sweden)

    Mneimneh Zeina M.

    2015-12-01

    Full Text Available Privacy is an important feature of the interview interaction mainly due to its potential effect on reporting information, especially sensitive information. Here we examine the effect of third-party presence on reporting both sensitive and relatively neutral outcomes. We investigate whether the effect of third-party presence on reporting sensitive information is moderated by the respondent’s need for social conformity and the respondent’s country of residence. Three types of outcomes are investigated: behavioral, attitudinal, and relatively neutral health events. Using data from 22,070 interviews and nine countries in the cross-national World Mental Health Survey Initiative, we fit multilevel logistic regression to study reporting effects on questions about suicidal behavior and marital ratings, and contrast these with questions about having high blood pressure, asthma, or arthritis. We find that there is an effect of third-party presence on reporting sensitive information and no effect on reporting of neutral information. Further, the effect of the interview privacy setting on reporting sensitive information is moderated by the need for social conformity and the cultural setting.

  18. A cultural evolutionary programming approach to automatic analytical modeling of electrochemical phenomena through impedance spectroscopy

    CERN Document Server

    Arpaia, Pasquale

    2009-01-01

    An approach to automatic analytical modeling of electrochemical impedance spectroscopy data by evolutionary programming based on cultural algorithms is proposed. A solution-search strategy based on a cultural mechanism is exploited for defining the equivalent-circuit model automatically: information on search advance is transmitted to all potential solutions, rather than only to a small inheriting subset, such as in a traditional genetic approach. Moreover, with respect to the state of the art, also specific information related to constraints on the application physics knowledge is transferred. Experimental results of the proposed approach implementation in impedance spectroscopy for general-purpose electrochemical circuit analysis and for corrosion monitoring and diagnosing are presented.

  19. Protect your heart: a culture-specific multimedia cardiovascular health education program.

    Science.gov (United States)

    Shah, Amy; Clayman, Marla L; Glass, Sara; Kandula, Namratha R

    2015-04-01

    South Asians, the second fastest growing racial/ethnic minority in the United States, have high rates of coronary heart disease. Few coronary heart disease prevention efforts target this population. The authors developed and tested a culture-specific, multimedia coronary heart disease prevention education program in English and Hindi for South Asians. Participants were recruited from community organizations in Chicago, Illinois, between June and October of 2011. Bilingual interviewers used questionnaires to assess participants' knowledge and perceptions before and after the patient education program. The change from pretest score to posttest score was calculated using a paired t test. Linear regression was used to determine the association between posttest scores and education and language. Participants' (N = 112) average age was 41 years, 67% had more than a high school education, and 50% spoke Hindi. Participants' mean pretest score was 15 (SD = 4). After the patient education program, posttest scores increased significantly among all participants (posttest score = 24, SD = 4), including those with limited English proficiency. Lower education was associated with a lower posttest score (β = -2.2, 95% CI [-0.68, -3.83]) in adjusted regression. A culture-specific, multimedia patient education program significantly improved knowledge and perceptions about coronary heart disease prevention among South Asian immigrants. Culturally salient multimedia education may be an effective and engaging way to deliver health information to diverse patient populations.

  20. The association between event learning and continuous quality improvement programs and culture of patient safety.

    Science.gov (United States)

    Mazur, Lukasz; Chera, Bhishamjit; Mosaly, Prithima; Taylor, Kinley; Tracton, Gregg; Johnson, Kendra; Comitz, Elizabeth; Adams, Robert; Pooya, Pegah; Ivy, Julie; Rockwell, John; Marks, Lawrence B

    2015-01-01

    To present our approach and results from our quality and safety program and to report their possible impact on our culture of patient safety. We created an event learning system (termed a "good catch" program) and encouraged staff to report any quality or safety concerns in real time. Events were analyzed to assess the utility of safety barriers. A formal continuous quality improvement program was created to address these reported events and make improvements. Data on perceptions of the culture of patient safety were collected using the Agency for Health Care Research and Quality survey administered before, during, and after the initiatives. Of 560 good catches reported, 367 could be ascribed to a specific step on our process map. The calculated utility of safety barriers was highest for those embedded into the pretreatment quality assurance checks performed by physicists and dosimetrists (utility score 0.53; 93 of 174) and routine checks done by therapists on the initial day of therapy. Therapists and physicists reported the highest number of good catches (24% each). Sixty-four percent of events were caused by performance issues (eg, not following standardized processes, including suboptimal communications). Of 31 initiated formal improvement events, 26 were successfully implemented and sustained, 4 were discontinued, and 1 was not implemented. Most of the continuous quality improvement program was conducted by nurses (14) and therapists (7). Percentages of positive responses in the patient safety culture survey appear to have increased on all dimensions (p quality improvement programs can be successfully implemented and that there are contemporaneous improvements in the culture of safety. Copyright © 2015 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

  1. Circulating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.

    Science.gov (United States)

    Walford, Geoffrey A; Ma, Yong; Christophi, Costas A; Goldberg, Ronald B; Jarolim, Petr; Horton, Edward; Mather, Kieren J; Barrett-Connor, Elizabeth; Davis, Jaclyn; Florez, Jose C; Wang, Thomas J

    2014-05-01

    We aimed to study the relationship between measures of adiposity, insulin sensitivity and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in the Diabetes Prevention Program (DPP). The DPP is a completed clinical trial. Using stored samples from this resource, we measured BMI, waist circumference (WC), an insulin sensitivity index (ISI; [1/HOMA-IR]) and NT-proBNP at baseline and at 2 years of follow-up in participants randomised to placebo (n = 692), intensive lifestyle intervention (n = 832) or metformin (n = 887). At baseline, log NT-proBNP did not differ between treatment arms and was correlated with baseline log ISI (p  0.05 for both). In regression models, the change in log NT-proBNP was positively associated with the change in log ISI (p < 0.005) in all three study groups after adjusting for changes in BMI and WC, but was not associated with the change in BMI or WC after adjusting for changes in log ISI. Circulating NT-proBNP was associated with a measure of insulin sensitivity before and during preventive interventions for type 2 diabetes in the DPP. This relationship persisted after adjustment for measures of adiposity and was consistent regardless of whether a participant was treated with placebo, intensive lifestyle intervention or metformin.

  2. 76 FR 59182 - Bureau of Educational and Cultural Affairs; Exchange Visitor Program; Summer Work Travel Program...

    Science.gov (United States)

    2011-09-23

    ... academic break (i.e., summer vacation) for a period not to exceed four months. On April 26, 2011, the... 2011 summer season and monitored the media for additional reports of program problems. As a result of... jobs for those whose pre- arranged placements were unsatisfactory); and policies for refunding deposits...

  3. Communication Skills, Cultural Sensitivity, and Collaboration in an Experiential Language Village Simulation

    Science.gov (United States)

    Clark, Allen; Minami, Nathan

    2015-01-01

    This article discusses five college students' experiences in a simulated full-immersion, Arabic-speaking language village and the impact of that experience on learners' beliefs about the power of collaborative learning, the critical importance of cultural awareness, the efficacy of learning languages within a functioning community of practice, and…

  4. Multiple case study in seven European countries regarding culture-sensitive classroom quality assessment

    NARCIS (Netherlands)

    Slot, P.L.; Cadima, Joana; Salminen, Jenni; Pastori, Giulia; Lerkkanen, Marja-Kristiina

    2016-01-01

    This report presents the findings of a multiple case study, conducted in seven European countries to examine common and culturally differing aspects of curriculum, pedagogy, and quality of Early Childhood Education and Care (ECEC) provisions in Europe. This multiple case study involved intensive dat

  5. Multiple case study in seven European countries regarding culture-sensitive classroom quality assessment

    NARCIS (Netherlands)

    Slot, P.L.|info:eu-repo/dai/nl/328192694; Cadima, Joana; Salminen, Jenni; Pastori, Giulia; Lerkkanen, Marja-Kristiina

    This report presents the findings of a multiple case study, conducted in seven European countries to examine common and culturally differing aspects of curriculum, pedagogy, and quality of Early Childhood Education and Care (ECEC) provisions in Europe. This multiple case study involved intensive

  6. Hawthorn (Crataegus monogyna Jacq.) extract exhibits atropine-sensitive activity in a cultured cardiomyocyte assay.

    Science.gov (United States)

    Salehi, Satin; Long, Shannon R; Proteau, Philip J; Filtz, Theresa M

    2009-01-01

    Hawthorn (Crataegus spp.) plant extract is used as a herbal alternative medicine for the prevention and treatment of various cardiovascular diseases. Recently, it was shown that hawthorn extract preparations caused negative chronotropic effects in a cultured neonatal murine cardiomyocyte assay, independent of beta-adrenergic receptor blockade. The aim of this study was to further characterize the effect of hawthorn extract to decrease the contraction rate of cultured cardiomyocytes. To test the hypothesis that hawthorn is acting via muscarinic receptors, the effect of hawthorn extract on atrial versus ventricular cardiomyocytes in culture was evaluated. As would be expected for activation of muscarinic receptors, hawthorn extract had a greater effect in atrial cells. Atrial and/or ventricular cardiomyocytes were then treated with hawthorn extract in the presence of atropine or himbacine. Changes in the contraction rate of cultured cardiomyocytes revealed that both muscarinic antagonists significantly attenuated the negative chronotropic activity of hawthorn extract. Using quinuclidinyl benzilate, L-[benzylic-4,4'-(3)H] ([(3)H]-QNB) as a radioligand antagonist, the effect of a partially purified hawthorn extract fraction to inhibit muscarinic receptor binding was quantified. Hawthorn extract fraction 3 dose-dependently inhibited [(3)H]-QNB binding to mouse heart membranes. Taken together, these findings suggest that decreased contraction frequency by hawthorn extracts in neonatal murine cardiomyocytes may be mediated via muscarinic receptor activation.

  7. The ESL Family Science Night: a model for culturally sensitive science education pedagogy

    National Research Council Canada - National Science Library

    Valadez, Gilbert; Moineau, Suzanne

    2010-01-01

    ... general findings and suggestions for further research and pre-service teacher education as it relates to teaching science pedagogy in a way that better serves minority children and their parents and/or guardians. Here, we are defining minority children as those that come from non-mainstream Anglo-American culture and are second language learners. L...

  8. Multiple case study in seven European countries regarding culture-sensitive classroom quality assessment

    NARCIS (Netherlands)

    Slot, P.L.|info:eu-repo/dai/nl/328192694; Cadima, Joana; Salminen, Jenni; Pastori, Giulia; Lerkkanen, Marja-Kristiina

    2016-01-01

    This report presents the findings of a multiple case study, conducted in seven European countries to examine common and culturally differing aspects of curriculum, pedagogy, and quality of Early Childhood Education and Care (ECEC) provisions in Europe. This multiple case study involved intensive dat

  9. Self-starvation in context: towards a culturally sensitive understanding of anorexia nervosa.

    Science.gov (United States)

    Lee, S

    1995-07-01

    Extreme forms of self-starvation can be traced across time and place, and may be construed using a variety of explanatory models. Curiously, the prevailing biomedical definition of anorexia nervosa has assigned primacy to the exclusive use of 'fat phobia' by the affected subjects to justify their diminished food intake. This paper assembles evidence to show that this culturally constructed version of fat phobic anorexia nervosa has neglected the full metaphorical significance of self-starvation and, when applied in a cross-cultural context, may constitute a category fallacy. By delegitimizing other rationales for non-eating and thereby barring subjective expressions, this regnant interpretive strategy may obscure clinicians' understanding of patients' lived experience, and even jeopardize their treatment. Nonetheless, it is a relatively simple task to attune the extant diagnostic criteria to a polythetic approach which will avert cultural parochialism in psychiatric theory and practice. As a corollary of the archival and ethnocultural study of extreme self-starvation, there is, contrary to epistemological assumptions embedded in the biomedical culture of contemporary psychiatry, no 'core psychopathology' of anorexia nervosa.

  10. Cuento Therapy. Folktales as a Culturally Sensitive Psychotherapy for Puerto Rican Children. Monograph No. 12.

    Science.gov (United States)

    Constantino, Giuseppe; And Others

    A seven-year project developing and testing cuento therapy, a form of child psychotherapy in which Puerto Rican mothers recount to their children folktales taken from Puerto Rican culture, is described and evaluated in this monograph. Chapter 1 explains how the research presented in later chapters fits into substantially broader patterns of…

  11. Human bone marrow cell culture: a sensitive method for determination of the biocompatibility of implant materials.

    Science.gov (United States)

    Wilke, A; Landgraff, M; Orth, J; Poenitz, H; Kienapfel, H; Boelte, K; Griss, P; Franke, R P

    1999-01-01

    The objective of this study was to develop a test method for determining the cytotoxicity and biocompatibility of various biomaterials that are used in orthopaedic surgery. This method is based on the use of a human bone marrow cell culture and was developed as an alternative to animal experiments. Human bone marrow cell culture has certain advantages over other cell culture models, as its results show a greater conformity with animal experimental results and clinical studies. Primary cell adherence, cell number, cell proliferation, production of extracellular matrix, cell viability and cell differentiation were used as indicative parameters of biocompatibility. After 2 weeks in culture, differences could be observed between the biomaterials with respect to these parameters. Cell numbers were greatest on the hydroxyapatite ceramic specimens, but were decreased on the titanium alloy specimens. Extracellular matrix hydroxyapatite production was high for ceramics, but reduced for titanium specimens. The polymers allowed only a few cells to adhere, and there were no signs of extracellular matrix production. The influence of biomaterials on differentiation of large numbers of cells was analysed by using flow cytophotometry. There were similar populations of T cells and monocytes on all specimens. However, extended B cell and granulocyte populations were observed with titanium and polyethylene.

  12. Using cognitive behaviour therapy with South Asian Muslims: Findings from the culturally sensitive CBT project.

    Science.gov (United States)

    Naeem, Farooq; Phiri, Peter; Munshi, Tariq; Rathod, Shanaya; Ayub, Muhhhamad; Gobbi, Mary; Kingdon, David

    2015-01-01

    It has been suggested that cognitive behaviour therapy (CBT) needs adaptation for it to be effective for patients from collectivistic cultures, as currently CBT is underpinned by individualistic values. In prior studies we have demonstrated that CBT could be adapted for Pakistani patients in Southampton, UK, and for local populations in Pakistan. Findings from these studies suggest that CBT can be adapted for patients from collectivistic cultures using a series of steps. In this paper we focus on these steps, and the process of adapting CBT for specific groups. The adaptation process should focus on three major areas of therapy, rather than simple translation of therapy manuals. These include (1) awareness of relevant cultural issues and preparation for therapy, (2) assessment and engagement, and (3) adjustments in therapy. We also discuss the best practice guidelines that evolved from this work to help therapists working with this population. We reiterate that CBT can be adapted effectively for patients from traditional cultures. This is, however, an emerging area in psychotherapy, and further work is required to refine the methodology and to test adapted CBT.

  13. A Family Day program enhances knowledge about medical school culture and necessary supports

    Directory of Open Access Journals (Sweden)

    Cushing Herbert E

    2004-03-01

    Full Text Available Abstract Background A Family Day program was implemented at Indiana University School of Medicine to educate the families and friends of in-coming medical students about the rigors of medical school and the factors that contribute to stress. Methods Surveys that assessed knowledge, beliefs, and attitudes about medical school were administered to participants before and after the program. Results After the program, participants showed a significant improvement in their understanding of medical school culture and the importance of support systems for medical students. Post-test scores improved by an average of 29% (P Conclusions The inclusion of family members and other loved ones in pre-matriculation educational programs may serve to mitigate the stress associated with medical school by enhancing the students' social support systems.

  14. The roles of effective communication and client engagement in delivering culturally sensitive care to immigrant parents of children with disabilities.

    Science.gov (United States)

    King, Gillian; Desmarais, Chantal; Lindsay, Sally; Piérart, Geneviève; Tétreault, Sylvie

    2015-01-01

    Delivering pediatric rehabilitation services to immigrant parents of children with disabilities requires the practice of culturally sensitive care. Few studies have examined the specific nature of culturally sensitive care in pediatric rehabilitation, especially the notions of effective communication and client engagement. Interviews were held with 42 therapists (10 social workers, 16 occupational therapists and 16 speech language pathologists) from two locations in Canada (Toronto and Quebec City). Data were analyzed using an inductive content analysis approach. Study themes included the importance and nature of effective communication and client engagement in service delivery involving immigrant parents. Participants discussed using four main types of strategies to engage immigrant parents, including understanding the family situation, building a collaborative relationship, tailoring practice to the client's situation and ensuring parents' understanding of therapy procedures. The findings illuminate the importance of effective, two-way communication in providing the mutual understanding needed by therapists to engage parents in the intervention process. The findings also richly describe the engagement strategies used by therapists. Clinical implications include recommendations for strategies for therapists to employ to engage this group of parents. Furthermore, the findings are applicable to service provision in general, as engaging families in a collaborative relationship through attention to their specific situation is a general principle of good quality, family-centered care. Implications for Rehabilitation Effective communication permeates the delivery of culturally sensitive care and provides mutual understanding, which is fundamental to client engagement. The findings illuminate the nature of "partnership" by indicating the role of collaborative therapist strategies in facilitating engagement. Four main strategies facilitate effective communication and

  15. Cultural practices and spiritual development for women in a Native American alcohol and drug treatment program.

    Science.gov (United States)

    Chong, Jenny; Fortier, Yvonne; Morris, Traci L

    2009-01-01

    The purpose of this study is to develop an instrument that can be used to identify clients' readiness for spiritual development and its relationship with their participation in American Indian/Alaskan Native practices. Female clients and staff from Guiding Star, the female residential substance abuse program at Native American Connections in Phoenix, Arizona, participated in the study. Two focus groups (8 Native and 5 non-Native clients) were conducted to determine the clients' attitudes toward cultural practices. A Native cultural practitioner was interviewed regarding the clients' spiritual needs and development. Finally, a survey on attitudes toward issues related to spirituality was conducted with 51 female clients. Readiness for spiritual development was found to be positively related to a positive outlook on life, being religious, or participating in American Indian/Alaska Native cultural activities.

  16. Culture microtitration: a sensitive method for quantifying Leishmania infantum in tissues of infected mice.

    OpenAIRE

    Buffet, P. A.; Sulahian, A.; Garin, Y J; Nassar, N.; Derouin, F

    1995-01-01

    We developed a microtitration method to determine the parasite burdens in homogenized organs of mice infected with Leishmania infantum. This method proved more sensitive than direct enumeration of amastigotes in stained organs, was appropriate for describing the kinetics of infection, and can be considered for physiopathological or pharmaceutical experimental studies.

  17. The Internal and External Constraints on Foreign Policy in India - Exploring culture and ethnic sensitivities

    DEFF Research Database (Denmark)

    Schmidt, Johannes Dragsbæk

    but there is no conclusive evidence in the literature to decide what determines what. There are important dynamics and interplays across the thin line between the domestic and international sphere especially in terms of understanding the reciprocal challenges related to how the factors of culture and ethnicity relate...... with the legitimacy of the state. The aim of the paper serves four purposes. To unpack and give a critical overview of the debates concerned with the internal and external aspects of India’s foreign policy; situate the literature dealing more specifically with domestic issues related to culture and ethnicity...... and outline the main approaches involved; to give an overview of how external factors impact foreign policy conduct and give an overview about India’s role in defining international norms and regulations; finally the paper gives some theoretical markers, suggestions and tentative concluding remarks....

  18. Self-Reliability and Motivation in a Nuclear Security Culture Enhancement Program

    Energy Technology Data Exchange (ETDEWEB)

    Crawford,C.; de Boer,G.; De Castro, K; Landers, Ph.D., J; Rogers, E

    2009-10-19

    The threat of nuclear terrorism has become a global concern. Many countries continue to make efforts to strengthen nuclear security by enhancing systems of nuclear material protection, control, and accounting (MPC&A). Though MPC&A systems can significantly upgrade nuclear security, they do not eliminate the "human factor." This paper will describe some of the key elements of a comprehensive, sustainable nuclear security culture enhancement program and how implementation can mitigate the insider threat.

  19. Cultural adaptation process for international dissemination of the strengthening families program.

    Science.gov (United States)

    Kumpfer, Karol L; Pinyuchon, Methinin; Teixeira de Melo, Ana; Whiteside, Henry O

    2008-06-01

    The Strengthening Families Program (SFP) is an evidence-based family skills training intervention developed and found efficacious for substance abuse prevention by U.S researchers in the 1980s. In the 1990s, a cultural adaptation process was developed to transport SFP for effectiveness trials with diverse populations (African, Hispanic, Asian, Pacific Islander, and Native American). Since 2003, SFP has been culturally adapted for use in 17 countries. This article reviews the SFP theory and research and a recommended cultural adaptation process. Challenges in international dissemination of evidence-based programs (EBPs) are discussed based on the results of U.N. and U.S. governmental initiatives to transport EBP family interventions to developing countries. The technology transfer and quality assurance system are described, including the language translation and cultural adaptation process for materials development, staff training, and on-site and online Web-based supervision and technical assistance and evaluation services to assure quality implementation and process evaluation feedback for improvements.

  20. Investigation of Various Tissue Culture Monolayers Sensitivity in Detection of Clostridium difficile Toxin

    Directory of Open Access Journals (Sweden)

    MH Salari

    2008-05-01

    Full Text Available Backround: Clostridium difficile is the most common cause of nosocomial diarrhea. It is usually a consequence of antibi­otic treatment, but sporadic cases can occur. The purpose of this study was to investigate five tissue culture monolayers sen­sitivity in detection of C. difficile-toxin. Methods: A total of 402 stool samples from patients with nosocomial diarrhea hospitalized in three hospitals of Tehran Uni­versity of Medical Sciences (TUMS were collected. The samples were cultured on a selective cycloserine cefoxitin fructose agar (CCFA and incubated in anaerobic conditions, at 37 °C for 4 days. Isolates were characterized to species level by con­ventional biochemical tests. Bacterial cytotoxicity was assayed on five tissue culture monolayers. Results: Our findings show that of the total patients, 24 toxigenic C. difficile (6% were isolated. All 24 C. difficile toxins showed cytotoxic effect at ³ 1:10 dilution on Hela, Hep2, Vero, McCoy and Mdck cells after 16, 20, 24, 24 and 30 hours, re­spectively. C. difficile toxin showed cytotoxic effect at ³ 1:100 dilutions only on Hela cell monolayer after 48 hours. Conclusion: Hela cell monolayer may be a satisfactory substitute for the detection of C. difficile toxin in clinical specimens.   

  1. Analysis of Culture and Drug Sensitivity Tests of Mycoplasmas for 387 Patients with Nongonococcal Urethritis (Cervicitis) in Chongqing

    Institute of Scientific and Technical Information of China (English)

    翟志芳; 郝飞; 钟白玉; 黄秀英; 唐书谦; 刁庆春

    2004-01-01

    Objective: To investigate the prevalence of mycoplasma infections and the sensitivity to antibiotics among patients with nongonococcal urethritis or cervicitis (NGU) in Chongqing. Methods: 387 NGU cases with mycoplasma-positive results upon culture were analysed retrospectively. RESULTS: The majority of patients with mycoplasma infections were in the 20-40 year old age group. No significant difference was found between males and females. Ureaplasma urealyticum is the main pathogen of these NGU cases and no clear relationship between its concentration and pathogenic ability was noted. Drug sensitivity was tested against nine antibiotics; the sensitivity rates to josamycin, minocycline and doxycycline were 94.06%, 88.89% and 86.82% respectively, while the resistance rates to lincomycin, ofloxacin, azithromycin and roxthromycin were 74.94%, 42.12%, 41.60% and 40.31% in turn. Conclusions: Josamycin, minocycline and doxycycline could be used as the first choice to treat NGU with mycoplasma infections in Chongqing. It is important to select antibiotics for NGU treatment with mycoplasma infections based on the results of drug sensitivity tests.

  2. A Nonlinear Programming Perspective on Sensitivity Calculations for Systems Governed by State Equations

    Science.gov (United States)

    Lewis, Robert Michael

    1997-01-01

    This paper discusses the calculation of sensitivities. or derivatives, for optimization problems involving systems governed by differential equations and other state relations. The subject is examined from the point of view of nonlinear programming, beginning with the analytical structure of the first and second derivatives associated with such problems and the relation of these derivatives to implicit differentiation and equality constrained optimization. We also outline an error analysis of the analytical formulae and compare the results with similar results for finite-difference estimates of derivatives. We then attend to an investigation of the nature of the adjoint method and the adjoint equations and their relation to directions of steepest descent. We illustrate the points discussed with an optimization problem in which the variables are the coefficients in a differential operator.

  3. The Sensitivity and Specificity of Potassium Hydroxide Smear and Fungal Culture Relative to Clinical Assessment in the Evaluation of Tinea Pedis: A Pooled Analysis

    Directory of Open Access Journals (Sweden)

    Jacob Oren Levitt

    2010-01-01

    Full Text Available Background. There are relatively few studies published examining the sensitivity and specificity of potassium hydroxide (KOH smear and fungal culture examination of tinea pedis. Objective. To evaluate the sensitivity and specificity of KOH smear and fungal culture for diagnosing tinea pedis. Methods. A pooled analysis of data from five similarly conducted bioequivalence trials for antifungal drugs was performed. Data from 460 patients enrolled in the vehicle arms of these studies with clinical diagnosis of tinea pedis supported by positive fungal culture were analyzed 6 weeks after initiation of the study to determine the sensitivity and specificity of KOH smear and fungal culture. Results. Using clinical assessment as the gold standard, the sensitivities for KOH smear and culture were 73.3% (95% CI: 66.3 to 79.5% and 41.7% (34.6 to 49.1%, respectively. The respective specificities for culture and KOH smear were 77.7% (72.2 to 82.5% and 42.5% (36.6 to 48.6%. Conclusion. KOH smear and fungal culture are complementary diagnostic tests for tinea pedis, with the former being the more sensitive test of the two, and the latter being more specific.

  4. An anthropological approach to teaching health sciences students cultural competency in a field school program.

    Science.gov (United States)

    Hutchins, Frank T; Brown, Lori DiPrete; Poulsen, Keith P

    2014-02-01

    International immersion experiences do not, in themselves, provide students with the opportunity to develop cultural competence. However, using an anthropological lens to educate students allows them to learn how to negotiate cultural differences by removing their own cultural filters and seeing events through the eyes of those who are culturally different. Faculty at the University of Wisconsin-Madison's Global Health Institute believed that an embedded experience, in which students engaged with local communities, would encourage them to adopt this Cultural Competency 2.0 position. With this goal in mind, they started the Field School for the Study of Language, Culture, and Community Health in Ecuador in 2003 to teach cultural competency to medical, veterinary, pharmacy, and nursing students. The program was rooted in medical anthropology and embraced the One Health initiative, which is a collaborative effort of multiple disciplines working locally, nationally, and globally to obtain optimal health for people, animals, and the environment. In this article, the authors identify effective practices and challenges for using a biocultural approach to educating students. In a semester-long preparatory class, students study the Spanish language, region-specific topics, and community engagement principles. While in Ecuador for five weeks, students apply their knowledge during community visits that involve homestays and service learning projects, for which they partner with local communities to meet their health needs. This combination of language and anthropological course work and community-based service learning has led to positive outcomes for the local communities as well as professional development for students and faculty.

  5. Success for All? The Role of the School Counselor in Creating and Sustaining Culturally Responsive Positive Behavior Interventions and Supports Programs

    Science.gov (United States)

    Betters-Bubon, Jennifer; Brunner, Todd; Kansteiner, Avery

    2016-01-01

    Successful implementation of Positive Behavior Interventions and Supports (PBIS) programs should include culturally responsive practices to reduce disproportionality in school discipline referrals and create effective learning environments for all students. Sustaining culturally responsive PBIS programs requires attention to student demographics…

  6. Effects of culture-sensitive adaptation of patient information material on usefulness in migrants: a multicentre, blinded randomised controlled trial.

    Science.gov (United States)

    Hölzel, Lars P; Ries, Zivile; Kriston, Levente; Dirmaier, Jörg; Zill, Jördis M; Rummel-Kluge, Christine; Niebling, Wilhelm; Bermejo, Isaac; Härter, Martin

    2016-11-23

    To evaluate the usefulness of culture-sensitive patient information material compared with standard translated material. Multicentre, double-blind randomised controlled trial. 37 primary care practices. 435 adult primary care patients with a migration background with unipolar depressive disorder or non-specific chronic low back pain were randomised. Patients who were unable to read in the language of their respective migration background were excluded. Sufficient data were obtained from 203 women and 106 men. The largest group was of Russian origin (202 patients), followed by those of Turkish (52), Polish (30) and Italian (25) origin. Intervention group: provision of culture-sensitive adapted material. provision of standard translated material. Primary outcome: patient-rated usefulness (USE) assessed immediately after patients received the material. patient-rated usefulness after 8 weeks and 6 months, symptoms of depression (PHQ-9), back pain (Back Pain Core Set) and quality of life (WHO-5) assessed at all time points. Usefulness was found to be significantly higher (t=1.708, one-sided p=0.04) in the intervention group (USE-score=65.08, SE=1.43), compared with the control group (61.43, SE=1.63), immediately after patients received the material, in the intention-to-treat analysis, with a mean difference of 3.65 (one-sided 95% lower confidence limit=0.13). No significant differences were found for usefulness at follow-up (p=0.16, p=0.71). No significant effect was found for symptom severity in depression (p=0.95, p=0.66, p=0.58), back pain (p=0.40, p=0.45, p=0.32) or quality of life (p=0.76, p=0.86, p=0.21), either immediately after receiving the material, or at follow-up (8 weeks; 6 months). Patients with a lower level of dominant society immersion benefited substantially and significantly more from the intervention than patients with a high level of immersion (p=0.005). Cultural adaptation of patient information material provides benefits over high quality

  7. Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures

    Science.gov (United States)

    Fraveto, Alice; Cardinale, Vincenzo; Bragazzi, Maria Consiglia; Giuliante, Felice; De Rose, Agostino Maria; Grazi, Gian Luca; Napoletano, Chiara; Semeraro, Rossella; Lustri, Anna Maria; Costantini, Daniele; Nevi, Lorenzo; Di Matteo, Sabina; Renzi, Anastasia; Carpino, Guido; Gaudio, Eugenio; Alvaro, Domenico

    2015-01-01

    We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N. 18 IHCCA patients) and evaluated for cell proliferation (MTS assay) and apoptosis (Caspase 3) after incubation (72 hours) with increasing concentrations of different drugs. In vivo, subcutaneous human tumor xenografts were evaluated. Primary cultures of mucin- and mixed-IHCCA were characterized by a different pattern of expression of cancer stem cell markers, and by a different drug sensitivity. Gemcitabine and the Gemcitabine-Cisplatin combination were more active in inhibiting cell proliferation in mixed-IHCCA while Cisplatin or Abraxane were more effective against mucin-IHCCA, where Abraxane also enhances apoptosis. 5-Fluoracil showed a slight inhibitory effect on cell proliferation that was more significant in mixed- than mucin-IHCCA primary cultures and, induced apoptosis only in mucin-IHCCA. Among Hg inhibitors, LY2940680 and Vismodegib showed slight effects on proliferation of both IHCCA subtypes. The tyrosine kinase inhibitors, Imatinib Mesylate and Sorafenib showed significant inhibitory effects on proliferation of both mucin- and mixed-IHCCA. The MEK 1/2 inhibitor, Selumetinib, inhibited proliferation of only mucin-IHCCA while the aminopeptidase-N inhibitor, Bestatin was more active against mixed-IHCCA. The c-erbB2 blocking antibody was more active against mixed-IHCCA while, the Wnt inhibitor, LGK974, similarly inhibited proliferation of mucin- and mixed-IHCCA. Either mucin- or mixed-IHCCA showed high sensitivity to nanomolar concentrations of the dual PI3-kinase/mTOR inhibitor, NVP-BEZ235. In vivo, in subcutaneous xenografts, either NVP-BEZ235 or Abraxane, blocked tumor growth. In conclusion, mucin- and mixed-IHCCA are characterized by a different drug sensitivity. Cisplatin, Abraxane and the MEK 1/2 inhibitor, Selumetinib were more

  8. Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures.

    Directory of Open Access Journals (Sweden)

    Alice Fraveto

    Full Text Available We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N. 18 IHCCA patients and evaluated for cell proliferation (MTS assay and apoptosis (Caspase 3 after incubation (72 hours with increasing concentrations of different drugs. In vivo, subcutaneous human tumor xenografts were evaluated. Primary cultures of mucin- and mixed-IHCCA were characterized by a different pattern of expression of cancer stem cell markers, and by a different drug sensitivity. Gemcitabine and the Gemcitabine-Cisplatin combination were more active in inhibiting cell proliferation in mixed-IHCCA while Cisplatin or Abraxane were more effective against mucin-IHCCA, where Abraxane also enhances apoptosis. 5-Fluoracil showed a slight inhibitory effect on cell proliferation that was more significant in mixed- than mucin-IHCCA primary cultures and, induced apoptosis only in mucin-IHCCA. Among Hg inhibitors, LY2940680 and Vismodegib showed slight effects on proliferation of both IHCCA subtypes. The tyrosine kinase inhibitors, Imatinib Mesylate and Sorafenib showed significant inhibitory effects on proliferation of both mucin- and mixed-IHCCA. The MEK 1/2 inhibitor, Selumetinib, inhibited proliferation of only mucin-IHCCA while the aminopeptidase-N inhibitor, Bestatin was more active against mixed-IHCCA. The c-erbB2 blocking antibody was more active against mixed-IHCCA while, the Wnt inhibitor, LGK974, similarly inhibited proliferation of mucin- and mixed-IHCCA. Either mucin- or mixed-IHCCA showed high sensitivity to nanomolar concentrations of the dual PI3-kinase/mTOR inhibitor, NVP-BEZ235. In vivo, in subcutaneous xenografts, either NVP-BEZ235 or Abraxane, blocked tumor growth. In conclusion, mucin- and mixed-IHCCA are characterized by a different drug sensitivity. Cisplatin, Abraxane and the MEK 1/2 inhibitor, Selumetinib

  9. Enhancing plant regeneration in tissue culture: a molecular approach through manipulation of cytokinin sensitivity.

    Science.gov (United States)

    Hill, Kristine; Schaller, G Eric

    2013-10-01

    Micropropagation is used for commercial purposes worldwide, but the capacity to undergo somatic organogenesis and plant regeneration varies greatly among species. The plant hormones auxin and cytokinin are critical for plant regeneration in tissue culture, with cytokinin playing an instrumental role in shoot organogenesis. Type-B response regulators govern the transcriptional output in response to cytokinin and are required for plant regeneration. In our paper published in Plant Physiology, we explored the functional redundancy among the 11 type-B Arabidopsis response regulators (ARRs). Interestingly, we discovered that the enhanced expression of one family member, ARR10, induced hypersensitivity to cytokinin in multiple assays, including callus greening and shoot induction of explants. Here we 1) discuss the hormone dependence for in vitro plant regeneration, 2) how manipulation of the cytokinin response has been used to enhance plant regeneration, and 3) the potential of the ARR10 transgene as a tool to increase the regeneration capacity of agriculturally important crop plants. The efficacy of ARR10 for enhancing plant regeneration likely arises from its ability to transcriptionally regulate key cytokinin responsive genes combined with an enhanced protein stability of ARR10 compared with other type-B ARRs. By increasing the capacity of key tissues and cell types to respond to cytokinin, ARR10, or other type-B response regulators with similar properties, could be used as a tool to combat the recalcitrance of some crop species to tissue culture techniques.

  10. FIRO-B scores and success in a positive peer-culture residential treatment program.

    Science.gov (United States)

    Lee, R E

    1996-02-01

    FIRO-B Wanted Inclusion, Wanted Affection, and Total scores discriminated between 28 adolescent boys who would be successful graduates of a positive peer-culture residential program and 29 who would not. Successful graduates had higher mean scores on these scales. Successful and unsuccessful residents did not differ in scores on Exner Rorschach Experience Balance, Experienced Stimulation, or Adjusted D. Likewise they did not differ in Verbal IQ or age. Openness to social relationships may be an important variable in assessing for whom group-based treatment will work. Where the capacity for relatedness is not present, staff in a group-based program may have to recognize and treat this if the program is to succeed.

  11. Cultured rat vascular smooth muscle cells are resistant to methylamine toxicity: no correlation to semicarbazide-sensitive amine oxidase

    Science.gov (United States)

    Langford, S. D.; Trent, M. B.; Boor, P. J.

    2001-01-01

    Methylamine (MA), a component of serum and a metabolite of nicotine and certain insecticides and herbicides, is metabolized by semicarbazide-sensitive amine oxidase (SSAO). MA is toxic to cultured human umbilical vein and calf pulmonary artery endothelial cells. Endothelial cells, which do not exhibit endogenous SSAO activity, are exposed to SSAO circulating in serum. In contrast, vascular smooth muscle cells (VSMC) do exhibit innate SSAO activity both in vivo and in vitro. This property, together with the critical localization of VSMC within the arterial wall, led us to investigate the potential toxicity of MA to VSMC. Cultured rat VSMC were treated with MA (10-5 to 1 M). In some cultures, SSAO was selectively inhibited with semicarbazide or MDL-72145 [(E)-2-(3,4-dimethoxyphenyl)-3-fluoroallylamine]. Cytotoxicity was measured via MTT, vital dye exclusion, and clonogenic assays. MA proved to be toxic to VSMC only at relatively high concentrations (LC(50) of 0.1 M). The inhibition of SSAO with semicarbazide or MDL-72145 did not increase MA toxicity, suggesting that the production of formaldehyde via tissue-bound, SSAO-mediated MA metabolism does not play a role in the minimal toxicity observed in isolated rat VSMC. The omission of fetal calf serum (FCS), which contains high SSAO activity, from media similarly showed little effect on cytotoxicity. We conclude that VSMC--in contrast to previous results in endothelial cells--are relatively resistant to MA toxicity, and SSAO does not play a role in VSMC injury by MA.

  12. Reduction in porphyrin excretion as a sensitive indicator of lead toxicity in primary cultures of adult rat hepatocytes.

    Science.gov (United States)

    Quintanilla-Vega, B; Hernandez, A; Mendoza-Figueroa, T

    1996-12-01

    Alterations of specific metabolic pathways can be used as sensitive indicators of toxicity by chemicals and can give valuable information on the mechanism(s) involved. Short-term effects of lead on hepatic haem biosynthesis were studied in an in vitro system. Primary cultures of adult rat hepatocytes were exposed for 24-48 hr to lead (0.024-3.6 mm), and excreted and intracellular porphyrins were measured in untreated and lead-treated cultures. Cytotoxicity, as estimated by enzyme leakage, and morphological alterations were also evaluated. Control hepatocytes produced porphyrins at a rate of 387 pmol/mg cellular protein/day. Most of the released and intracellular porphyrins were protoporphyrins, although uro- and coproporphyrins were also detected in lower amounts. After 24 hr of exposure to 0.1-3.6 mm Pb(2+) , excreted porphyrins decreased by 24-92% and intracellular porphyrins by 36-60%, while 48 hr of exposure to 0.024-3.6 mm Pb(2+) caused a progressive reduction of 77-97% in porphyrin excretion and of 49-67% in intracellular porphyrins. Lead exposure also produced a differential decrease of proto-, copro- and uro-porphyrin excretion. These lead effects can be explained mainly by inhibition of the enzyme 5-aminolaevulinate dehydratase, resulting in a decreased monopyrrole supply for porphyrin biosynthesis, and probably by inhibition of the enzyme uroporphyrinogen decarboxylase. Morphological alterations and enzyme leakage were detected only after 24 hr of exposure to 2.4 mm and 48 hr of exposure to 3.6 mm Pb(2+), respectively. The results show that changes in porphyrin production, and particularly in their excretion, in cultured rat hepatocytes are useful indicators of lead toxicity, since they are more sensitive than enzyme leakage and can give preliminary information on the enzyme(s) that could be affected. They also suggest the potential benefits of the use of this method for the evaluation of compounds that alter haem biosynthesis.

  13. Capillary size exclusion chromatography with picogram sensitivity for analysis of monoclonal antibodies purified from harvested cell culture fluid.

    Science.gov (United States)

    Rea, Jennifer C; Moreno, G Tony; Vampola, Lisa; Lou, Yun; van Haan, Bjorn; Tremintin, Guillaume; Simmons, Laura; Nava, Adrian; Wang, Yajun Jennifer; Farnan, Dell

    2012-01-06

    Size exclusion chromatography (SEC) is widely used in the characterization and quality control of therapeutic proteins to detect aggregates. Aggregation is a carefully monitored quality attribute from the earliest stages of clinical development owing to the possibility of eliciting an immunogenic response in the patient. During early stage molecule assessment for cell culture production, small-scale screening experiments are performed to permit rapid turn-around of results so as to not delay timelines. We report the development of a capillary SEC methodology for preliminary molecule assessment to support the evaluation of therapeutic candidates at an early stage of development. By making several key modifications to a commercially available liquid chromatography system, we demonstrate a platform process to perform capillary SEC with excellent precision, picogram sensitivity and good ruggedness. The limit of quantitation was determined to be approximately 15 pg; picogram sensitivity for SEC analysis of monoclonal antibodies had not been achieved prior to this work. In addition, we have developed a method to capture low levels of antibody (1 μg/mL) from harvested cell culture fluid (HCCF) for capillary SEC analysis. Up to 40% recovery efficiency was achieved using this micro-recovery method on 3 mL HCCF samples. Using early stage cell culture transient transfection samples, which typically have much lower titers than stable cell line samples, we demonstrate a consistent method for analyzing aggregates in low protein concentration HCCF samples for molecule assessment and early stage candidate screening. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. Master's Degree Program in Scientific and Cultural Communication: Preliminary reports on an innovative experience in Brazil

    Directory of Open Access Journals (Sweden)

    Carlos A. Vogt

    2009-03-01

    Full Text Available The multidisiciplinary Master’s Degree Program in Scientific and Cultural Communication (MDCC began in the first semester of 2007. It is offered by the Laboratory of Advanced Studies in Journalism (Labjor of the Creativity Development Nucleus (NUDECRI and by the Institute of Language Studies (IEL, both of which are entities the State University of Campinas (UNICAMP. The program is also supported by the Department of Scientific and Technological Policy (DPCT of the Geosciences Institute (IG and by MediaTec – Media and Communication Technologies Laboratory of the Multimedia Department (DMM of the Art Institute (IA. The objective of the MDCC is to train and enable researchers with in-depth theoretical knowledge about current questions related to science communication. A global vision of the systems of science and technology are joined together with an understanding of a solid, contemporary literary and cultural repertoire. The interaction among subjects offered in the MDCC seeks to provide an education that allows critical reflection about the main accomplishments of science, technology and culture in our current society and the way in which the mass or specialized media have worked in order to communicate these accomplishments. The areas of research focus on the analysis of cultural production and science communication within the most diverse means of information, such as print, radio, television and electronic media. There is a special emphasis on areas such as science and technical history and the sociology of science, as well as other spaces of science and cultural communication, such as museums, forums and events.

  15. Assessing services with communicatively impaired bilingual adults in culturally and linguistically diverse neurorehabilitation programs.

    Science.gov (United States)

    Centeno, José G

    2015-01-01

    The combined effect of the steady increase in cultural and linguistic diversity and epidemiological factors in minority populations is estimated to continue having an impact on adult neurorehabilitation programs in the country, particularly in the number of bilingual individuals receiving clinical services. No comprehensive assessment of the present professional and clinical realities in service delivery to communicatively impaired adults in culturally and linguistically diverse (CLD) neurorehabilitation contexts has been conducted. The current survey research was undertaken to examine current professional training, clinical practices, and challenges in the services rendered to the steadily increasing numbers of communicatively disordered adults in CLD neurorehabilitation programs with a special focus on bilingual persons. A 36-question, 6-section survey was administered to health care-based SLPs working with adults to examine multiple factors regarding work setting and caseload, professional training, clinical tools and procedures, service delivery issues, and suggestions to improve clinical work with bilingual adults in CLD neurorehabilitation environments. Results support that SLPs presently make sensible decisions to serve communicatively disordered bilingual adults with neuropathologies despite training gaps and scant clinical resources. Responses additionally highlight critical areas to improve professional preparation and available resources. Results are discussed in terms of strengths and weaknesses as well as their implications to professional education and target research areas in order to minimize present gaps in service delivery with bilingual speakers in CLD adult neurorehabilitation programs. As a result of this activity, the reader will be able to: (1) Discuss the demographic and epidemiological factors that suggest a continued increase in the number of communicatively impaired bilingual adults in CLD neurorehabilitation programs. (2) Describe

  16. Improving Human-Computer Interaction by Developing Culture-sensitive Applications based on Common Sense Knowledge

    CERN Document Server

    Anacleto, Junia Coutinho

    2010-01-01

    The advent of Web 3.0, claiming for personalization in interactive systems (Lassila & Hendler, 2007), and the need for systems capable of interacting in a more natural way in the future society flooded with computer systems and devices (Harper et al., 2008) show that great advances in HCI should be done. This chapter presents some contributions of LIA for the future of HCI, defending that using common sense knowledge is a possibility for improving HCI, especially because people assign meaning to their messages based on their common sense and, therefore, the use of this knowledge in developing user interfaces can make them more intuitive to the end-user. Moreover, as common sense knowledge varies from group to group of people, it can be used for developing applications capable of giving different feedback for different target groups, as the applications presented along this chapter illustrate, allowing, in this way, interface personalization taking into account cultural issues. For the purpose of using com...

  17. Collectivism in Smoking Prevention Programs for Hispanic Preadolescents: Raising the Ante on Cultural Sensitivity

    Science.gov (United States)

    Gonzalez-Blanks, Ana G.; Lopez, Stella G.; Garza, Raymond T.

    2012-01-01

    The present study examines collectivist influences in preventing smoking among Hispanic youths. Using a pretest/posttest design, sixth-graders received a collectivist or standard curriculum. Both curricula contained knowledge-based facts about smoking. The collectivist condition included an interdependent perspective. Compared to the standard…

  18. Selective sensitiveness of mesenchymal stem cells to shock waves leads to anticancer effect in human cancer cell co-cultures.

    Science.gov (United States)

    Foglietta, Federica; Duchi, Serena; Canaparo, Roberto; Varchi, Greta; Lucarelli, Enrico; Dozza, Barbara; Serpe, Loredana

    2017-03-15

    Mesenchymal stem cells (MSC) possess the distinctive feature of homing in on and engrafting into the tumor stroma making their therapeutic applications in cancer treatment very promising. Research into new effectors and external stimuli, which can selectively trigger the release of cytotoxic species from MSC toward the cancer cells, significantly raises their potential. Shock waves (SW) have recently gained recognition for their ability to induce specific biological effects, such as the local generation of cytotoxic reactive oxygen species (ROS) in a non-invasive and tunable manner. We thus investigate whether MSC are able to generate ROS and, in turn, affect cancer cell growth when in co-culture with human glioblastoma (U87) or osteosarcoma (U2OS) cells and exposed to SW. MSC were found to be the cell line that was most sensitive to SW treatment as shown by SW-induced ROS production and cytotoxicity. Notably, U87 and U2OS cancer cell growth was unaffected by SW exposure. However, significant decreases in cancer cell growth, 1.8 fold for U87 and 2.3 fold for U2OS, were observed 24h after the SW treatment of MSC co-cultures with cancer cells. The ROS production induced in MSC by SW exposure was then responsible for lipid peroxidation and cell death in U87 and U2OS cells co-cultured with MSC. This experiment highlights the unique ability of MSC to generate ROS upon SW treatment and induce the cell death of co-cultured cancer cells. SW might therefore be proposed as an innovative tool for MSC-mediated cancer treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Initiatives to improve feedback culture in the final year of a veterinary program.

    Science.gov (United States)

    Warman, Sheena M; Laws, Emma J; Crowther, Emma; Baillie, Sarah

    2014-01-01

    Despite the recognized importance of feedback in education, student satisfaction with the feedback process in medical and veterinary programs is often disappointing. We undertook various initiatives to try to improve the feedback culture in the final clinical year of the veterinary program at the University of Bristol, focusing on formative verbal feedback. The initiatives included E-mailed guidelines to staff and students, a faculty development workshop, and a reflective portfolio task for students. Following these initiatives, staff and students were surveyed regarding their perceptions of formative feedback in clinical rotations, and focus groups were held to further explore issues. The amount of feedback appeared to have increased, along with improved recognition of feedback by students and increased staff confidence and competence in the process. Other themes that emerged included inconsistencies in feedback among staff and between rotations; difficulties with giving verbal feedback to students, particularly when it relates to professionalism; the consequences of feedback for both staff and students; changes and challenges in students' feedback-seeking behavior; and the difficulties in providing accurate, personal end-of-rotation assessments. This project has helped improve the feedback culture within our clinics; the importance of sustaining and further developing the feedback culture is discussed in this article.

  20. A weight-loss intervention program designed for Mexican-American women: Cultural adaptations and results

    Science.gov (United States)

    Lindberg, Nangel M.; Stevens, Victor J.; Vega-López, Sonia; Kauffman, Tia; Calderón, Mariana Rosales; Cervantes, María Antonieta

    2013-01-01

    Background This study assessed the feasibility of a culturally-appropriate weight-loss intervention targeting obese Spanish-speaking Mexican women. Methods This 12-month weight-loss program was based on behavioral interventions previously used successfully with English-speaking participants. Cultural adaptations included: female interventionists, minimal written materials, emphasis on group activities, focus on Mexican traditions and beliefs, and skill-building approach to food measurement. All sessions were conducted in Spanish. The study had few exclusionary criteria, which allowed participation of women with a wide range of literacy levels. Results Recruitment exceeded expectations, with 47 participants enrolling in the program. Not counting participants who became pregnant during the study, attendance at 6 and 12 months was 62% and 50% respectively. Mean weight loss at 6 and 12 months was 5.3 kg and 7.2 kg, respectively, with a mean reduction in BMI of 4.0 kg/m2 and 5.5 kg/m2 from baseline to 6 and 12 months, respectively. Discussion This pilot study shows that it is feasible to develop and implement culturally-appropriate behavioral lifestyle interventions for obesity treatment in Mexican-American women. PMID:22460538

  1. Culturally sensitive assessments as a strength-based approach to wellness in Native communities: A community-based participatory research project.

    Science.gov (United States)

    Verney, Steven P; Avila, Magdalena; Espinosa, Patricia Rodríguez; Cholka, Cecilia Brooke; Benson, Jennifer G; Baloo, Aihsa; Pozernick, Caitlin Devin

    2016-01-01

    American Indians and Alaska Natives (AI/ANs) have a unique, traumatic, and alienating history of education in the U.S., which may be directly related to overall health and well-being. Community engagement is critical in well-being research with Native communities, especially when investigating culturally sensitive topics, such as early education experiences. This study investigates the value of a community-based participatory research approach in gaining valuable culturally sensitive information from Native people in a respectful manner. Assessment participation and feedback are analyzed and presented as indicators of Native participant engagement success in a potentially sensitive research project exploring early education experiences.

  2. Validation of a provider self-report inventory for measuring patient-centered cultural sensitivity in health care using a sample of medical students.

    Science.gov (United States)

    Mirsu-Paun, Anca; Tucker, Carolyn M; Herman, Keith C; Hernandez, Caridad A

    2010-04-01

    The paper describes the construction and initial evaluation of the new Tucker-Culturally Sensitive Health Care Inventory (T-CSHCI) Provider Form, which was developed to address the shortcomings of existing similar measures. Two hundred seventeen (217) 3rd and 4th year medical students completed the T-CSHCI-Provider Form. Factor analysis was used to identify non-overlapping items. The final solution produced five factors: patient-centeredness, interpersonal skills, disrespect/disempowerment, competence, and cultural knowledge/responsiveness. The five T-CSHCI-Provider Form factors/subscales proved to be reliable and were associated with related constructs as hypothesized. This study provides initial evidence that the T-CSHCI-Provider Form measures independent dimensions of patient-centered culturally sensitive health care as perceived by medical students. Recommendations for ways in which the T-CSHCI Provider Form can be used to guide culturally sensitive health care training are provided.

  3. Comparison of illumigene Group A Streptococcus Assay with Culture of Throat Swabs from Children with Sore Throats in the New Zealand School-Based Rheumatic Fever Prevention Program.

    Science.gov (United States)

    Upton, Arlo; Bissessor, Liselle; Farrell, Elizabeth; Shulman, Stanford T; Zheng, Xiaotian; Lennon, Diana

    2016-01-01

    Group A streptococcal (GAS) pharyngitis is a particularly important condition in areas of New Zealand where the incidence of acute rheumatic fever remains unacceptably high. Prompt diagnosis and treatment of GAS pharyngitis are cornerstones of the Rheumatic Fever Prevention Programme, but these are hindered by the turnaround time of culture. Tests with excellent performance and rapid turnaround times are needed. For this study, throat swabs (Copan ESwabs) were collected from schoolchildren self-identifying with a sore throat. Samples were tested by routine culture and the illumigene GAS assay using loop-mediated isothermal amplification. Discrepant results were resolved by retesting of the same specimen by an alternative molecular assay. Seven hundred fifty-seven throat swab specimens were tested by both methods. The performance characteristics of the illumigene assay using culture on blood agar as the "gold standard" and following discrepancy analysis were as follows: sensitivity, 82% and 87%, respectively; specificity, 93% and 98%, respectively; positive predictive value, 61% and 88%, respectively; and negative predictive value, 97% and 97%, respectively. In our unique setting of a school-based throat swabbing program, the illumigene assay did not perform quite as well as described in previous reports. Despite this, its improved sensitivity and rapid turnaround time compared with those of culture are appealing.

  4. The impact on attitudes towards cultural difference of participation in a health focused study abroad program.

    Science.gov (United States)

    Inglis, A; Rolls, C; Kristy, S

    2000-01-01

    The changes in attitudes towards cultural difference of seventeen participants in a three-week community health study abroad program to Nepal were compared with the changes in attitudes of a similar group who did not participate in the tour. Participants in the tour group were surveyed eight weeks prior to departure and in the last week of the tour using a twenty-six item questionnaire employing a six-point forced-choice response scale. The responses of participants in the tour group showed significant shifts in relation to eight items compared while the responses for the control group showed no significant shifts. Observed student advantages of participation in this study tour included the development of independent behaviour and positive cultural adjustment and adaptation.

  5. Working with Jewish ultra-orthodox patients: guidelines for a culturally sensitive therapy.

    Science.gov (United States)

    Bilu, Y; Witztum, E

    1993-06-01

    The epistemological gap between the medical reality of mental health practitioners and the sacred reality of their Jewish ultra-orthodox patients poses a major challenge for therapy. Based on our work with psychiatric patients from the ultra-orthodox community of northern Jerusalem, we propose a set of guidelines to cope with this challenge. Basically, we seek to incorporate religiously congruent elements, composed of metaphoric images, narratives and actions, into the wide range of our "secular" treatment modalities in order to respond to the patient's suffering, often expressed through distinctively religious idioms of distress. This endeavor calls for "a temporary suspension of disbelief" on both sides. The guidelines presented include three sets of factors which appear pertinent to working with ultra-orthodox patients. The first set is contextual in nature, dealing with the image of the clinic and its physical setting; the second discusses the necessary role requisites of the therapists; and the third one, accorded a central importance, deals on various levels with the therapeutic interventions administered in terms of form and content. Several case vignettes are presented to illustrate three classes of religiously informed interventions: healing rituals, dream interpretation, and the use of culturally congruent metaphors and stories. In the concluding part we discuss ethical and instrumental issues that the proposed therapeutic guidelines may raise.

  6. Medical Ethnobotany in Europe: From Field Ethnography to a More Culturally Sensitive Evidence-Based CAM?

    Science.gov (United States)

    Quave, Cassandra L.; Pardo-de-Santayana, Manuel; Pieroni, Andrea

    2012-01-01

    European folk medicine has a long and vibrant history, enriched with the various documented uses of local and imported plants and plant products that are often unique to specific cultures or environments. In this paper, we consider the medicoethnobotanical field studies conducted in Europe over the past two decades. We contend that these studies represent an important foundation for understanding local small-scale uses of CAM natural products and allow us to assess the potential for expansion of these into the global market. Moreover, we discuss how field studies of this nature can provide useful information to the allopathic medical community as they seek to reconcile existing and emerging CAM therapies with conventional biomedicine. This is of great importance not only for phytopharmacovigilance and managing risk of herb-drug interactions in mainstream patients that use CAM, but also for educating the medical community about ethnomedical systems and practices so that they can better serve growing migrant populations. Across Europe, the general status of this traditional medical knowledge is at risk due to acculturation trends and the urgency to document and conserve this knowledge is evident in the majority of the studies reviewed. PMID:22899952

  7. Medical Ethnobotany in Europe: From Field Ethnography to a More Culturally Sensitive Evidence-Based CAM?

    Directory of Open Access Journals (Sweden)

    Cassandra L. Quave

    2012-01-01

    Full Text Available European folk medicine has a long and vibrant history, enriched with the various documented uses of local and imported plants and plant products that are often unique to specific cultures or environments. In this paper, we consider the medicoethnobotanical field studies conducted in Europe over the past two decades. We contend that these studies represent an important foundation for understanding local small-scale uses of CAM natural products and allow us to assess the potential for expansion of these into the global market. Moreover, we discuss how field studies of this nature can provide useful information to the allopathic medical community as they seek to reconcile existing and emerging CAM therapies with conventional biomedicine. This is of great importance not only for phytopharmacovigilance and managing risk of herb-drug interactions in mainstream patients that use CAM, but also for educating the medical community about ethnomedical systems and practices so that they can better serve growing migrant populations. Across Europe, the general status of this traditional medical knowledge is at risk due to acculturation trends and the urgency to document and conserve this knowledge is evident in the majority of the studies reviewed.

  8. Preparation and participation of undergraduate students to inform culturally sensitive research.

    Science.gov (United States)

    Wells, Jo Nell; Cagle, Carolyn Spence

    2009-07-01

    Most student work as research assistants occurs at the graduate level of nursing education, and little is known about the role of undergraduate students as research assistants (RAs) in major research projects. Based on our desire to study Mexican American (MA) cancer caregivers, we needed bilingual and bicultural RAs to serve as data collectors with women who spoke Spanish and possessed cultural beliefs that influenced their caregiving. Following successful recruitment, orientation, and mentoring based on Bandura's social learning theory [Bandura, A., 2001. Social learning theory: an agentic perspective. Annual Review of Psychology 52, 1-26] and accepted teaching-learning principles, RAs engaged in various behaviors that facilitated study outcomes. Faculty researchers, RAs, and study participants benefitted greatly from the undergraduate student involvement in this project. This article describes successful student inclusion approaches, ongoing faculty-RA interactions, and lessons learned from the research team experience. Guidelines discussed support the potential for making the undergraduate RA role a useful and unique learning experience.

  9. Ideal for Whom? A Cultural Analysis of Ideal Worker Norms in Higher Education and Student Affairs Graduate Programs

    Science.gov (United States)

    Sallee, Margaret W.

    2016-01-01

    This chapter explores the consequences of ideal worker norms for graduate student-parents in higher education and student affairs programs. Using Schein's (2004) levels of culture as a conceptual lens, this chapter considers the ways that programmatic structures and interactions with faculty and peers reflect and reproduce a culture across…

  10. The effectiveness of cultural competence programs in ethnic minority patient-centered health care--a systematic review of the literature.

    Science.gov (United States)

    Renzaho, A M N; Romios, P; Crock, C; Sønderlund, A L

    2013-07-01

    To examine the effectiveness of patient-centered care (PCC) models, which incorporate a cultural competence (CC) perspective, in improving health outcomes among culturally and linguistically diverse patients. The search included seven EBSCO-host databases: Academic Search Complete, Academic Search Premier, CINAHL with Full Text, Global Health, MEDLINE with Full Text, PsycINFO PsycARTICLES, PsycEXTRA, Psychology and Behavioural Sciences Collection and Pubmed, Web of Knowledge and Google Scholar. The review was undertaken following the preferred reporting items for systematic reviews and meta-analyses, and the critical appraisals skill program guidelines, covering the period from January 2000 to July 2011. Data extraction Data were extracted from the studies using a piloted form, including fields for study research design, population under study, setting, sample size, study results and limitations. The initial search identified 1450 potentially relevant studies. Only 13 met the inclusion criteria. Of these, 11 were quantitative studies and 2 were qualitative. The conclusions drawn from the retained studies indicated that CC PCC programs increased practitioners' knowledge, awareness and cultural sensitivity. No significant findings were identified in terms of improved patient health outcomes. PCC models that incorporate a CC component are increased practitioners' knowledge about and awareness of dealing with culturally diverse patients. However, there is a considerable lack of research looking into whether this increase in practitioner knowledge translates into better practice, and in turn improved patient-related outcomes. More research examining this specific relationship is, thus, needed.

  11. Identification and control of dissolved oxygen in hybridoma cell culture in a shear sensitive environment.

    Science.gov (United States)

    Simon, L; Karim, M N

    2001-01-01

    The productivity of mammalian cells can be enhanced by facilitating adequate oxygen transfer into the cultivation medium. However, current methods of controlling dissolved oxygen (DO) fail to account for alterations in medium composition during the course of the fermentation. These changes, which directly affect gas solubility and overall mass transfer coefficient, may be significant and deteriorate controller's performance in the long run. In this paper, the applications of Generalized Predictive Controllers (GPC) to DO control were investigated in a shear sensitive environment and compared to PID and Model Predictive Controllers (MPC). Input and output data for system identification were initially generated by varying the composition of oxygen fed into the bioreactor from 0 to 0.21 mol % while keeping the total inlet gas flow rate at 8.75 vvm. The process was identified using an AutoRegressive model with eXogeneous inputs (ARX) model and tested on different data sets. The model parameters were then correlated with the overall mass transfer coefficients. In simulation tests, the output of the PID controller switched from minimum to maximum values while more continuous control signals were obtained with the MPC and GPC controllers. When tested in a cell-free medium, all three controllers were able to track setpoint changes with some chattering observed in the control signals. The GPC outperformed the MPC and PID controllers when applied to the cultivation of hybridoma cells.

  12. A Sensitive Sensor Cell Line for the Detection of Oxidative Stress Responses in Cultured Human Keratinocytes

    Directory of Open Access Journals (Sweden)

    Ute Hofmann

    2014-06-01

    Full Text Available In the progress of allergic and irritant contact dermatitis, chemicals that cause the generation of reactive oxygen species trigger a heat shock response in keratinocytes. In this study, an optical sensor cell line based on cultured human keratinocytes (HaCaT cells expressing green fluorescent protein (GFP under the control of the stress-inducible HSP70B’ promoter were constructed. Exposure of HaCaT sensor cells to 25 µM cadmium, a model substance for oxidative stress induction, provoked a 1.7-fold increase in total glutathione and a ~300-fold induction of transcript level of the gene coding for heat shock protein HSP70B’. An extract of Arnica montana flowers resulted in a strong induction of the HSP70B’ gene and a pronounced decrease of total glutathione in keratinocytes. The HSP70B’ promoter-based sensor cells conveniently detected cadmium-induced stress using GFP fluorescence as read-out with a limit of detection of 6 µM cadmium. In addition the sensor cells responded to exposure of cells to A. montana extract with induction of GFP fluorescence. Thus, the HaCaT sensor cells provide a means for the automated detection of the compromised redox status of keratinocytes as an early indicator of the development of human skin disorders and could be applied for the prediction of skin irritation in more complex in vitro 3D human skin models and in the development of micro-total analysis systems (µTAS that may be utilized in dermatology, toxicology, pharmacology and drug screenings.

  13. A sensitive sensor cell line for the detection of oxidative stress responses in cultured human keratinocytes.

    Science.gov (United States)

    Hofmann, Ute; Priem, Melanie; Bartzsch, Christine; Winckler, Thomas; Feller, Karl-Heinz

    2014-06-25

    In the progress of allergic and irritant contact dermatitis, chemicals that cause the generation of reactive oxygen species trigger a heat shock response in keratinocytes. In this study, an optical sensor cell line based on cultured human keratinocytes (HaCaT cells) expressing green fluorescent protein (GFP) under the control of the stress-inducible HSP70B' promoter were constructed. Exposure of HaCaT sensor cells to 25 µM cadmium, a model substance for oxidative stress induction, provoked a 1.7-fold increase in total glutathione and a ~300-fold induction of transcript level of the gene coding for heat shock protein HSP70B'. An extract of Arnica montana flowers resulted in a strong induction of the HSP70B' gene and a pronounced decrease of total glutathione in keratinocytes. The HSP70B' promoter-based sensor cells conveniently detected cadmium-induced stress using GFP fluorescence as read-out with a limit of detection of 6 µM cadmium. In addition the sensor cells responded to exposure of cells to A. montana extract with induction of GFP fluorescence. Thus, the HaCaT sensor cells provide a means for the automated detection of the compromised redox status of keratinocytes as an early indicator of the development of human skin disorders and could be applied for the prediction of skin irritation in more complex in vitro 3D human skin models and in the development of micro-total analysis systems (µTAS) that may be utilized in dermatology, toxicology, pharmacology and drug screenings.

  14. Institutional, Financial, Legal, and Cultural Factors in a Distance Learning Program.

    Science.gov (United States)

    Blakeman, Rachel; Haseley, Dennis

    2015-06-01

    As psychoanalytic institutes evolve, adapting to the contemporary financial and social environment, the integration of new technologies into psychoanalytic education presents opportunities for expansion to candidates residing beyond the usual geographic boundaries. While the teaching of analytic content through distance learning programs appears to be relatively straightforward, factors including legalities, traditional mind-sets, and cross-cultural issues need to be considered as complicating the situation, as illustrated by one U.S. institute's distance learning initiative with a group in South Korea. © 2015 by the American Psychoanalytic Association.

  15. The PRIDE (Partnership to Improve Diabetes Education) Toolkit: Development and Evaluation of Novel Literacy and Culturally Sensitive Diabetes Education Materials.

    Science.gov (United States)

    Wolff, Kathleen; Chambers, Laura; Bumol, Stefan; White, Richard O; Gregory, Becky Pratt; Davis, Dianne; Rothman, Russell L

    2016-02-01

    Patients with low literacy, low numeracy, and/or linguistic needs can experience challenges understanding diabetes information and applying concepts to their self-management. The authors designed a toolkit of education materials that are sensitive to patients' literacy and numeracy levels, language preferences, and cultural norms and that encourage shared goal setting to improve diabetes self-management and health outcomes. The Partnership to Improve Diabetes Education (PRIDE) toolkit was developed to facilitate diabetes self-management education and support. The PRIDE toolkit includes a comprehensive set of 30 interactive education modules in English and Spanish to support diabetes self-management activities. The toolkit builds upon the authors' previously validated Diabetes Literacy and Numeracy Education Toolkit (DLNET) by adding a focus on shared goal setting, addressing the needs of Spanish-speaking patients, and including a broader range of diabetes management topics. Each PRIDE module was evaluated using the Suitability Assessment of Materials (SAM) instrument to determine the material's cultural appropriateness and its sensitivity to the needs of patients with low literacy and low numeracy. Reading grade level was also assessed using the Automated Readability Index (ARI), Coleman-Liau, Flesch-Kincaid, Fry, and SMOG formulas. The average reading grade level of the materials was 5.3 (SD 1.0), with a mean SAM of 91.2 (SD 5.4). All of the 30 modules received a "superior" score (SAM >70%) when evaluated by 2 independent raters. The PRIDE toolkit modules can be used by all members of a multidisciplinary team to assist patients with low literacy and low numeracy in managing their diabetes. © 2015 The Author(s).

  16. Translation, cross-cultural adaptation, and validity of the Korean version of the pain sensitivity questionnaire in chronic pain patients.

    Science.gov (United States)

    Kim, Ho-Joong; Ruscheweyh, Ruth; Yeo, Ji-Hyun; Cho, Hyeon-Guk; Yi, Je-Min; Chang, Bong-Soon; Lee, Choon-Ki; Yeom, Jin S

    2014-11-01

    The purpose of this study was to translate pain sensitivity questionnaires (PSQ) into the Korean language, perform a cross-cultural adaption of the PSQ, and validate the Korean version of PSQ in patients with degenerative spinal disease. The PSQ was translated forward and backward, cross-culturally adapted by 2 independent translators, and approved by an expert committee. The final Korean version of the PSQ was tested on 72 patients with degenerative spinal disease. Test-retest reliability was evaluated for 60 patients (83%) who completed the second assessment in an interval of 4 weeks. The mean PSQ-minor, PSQ-moderate, and PSQ-total (standard deviation [SD]) were 5.40 (2.02), 6.46 (1.98), and 5.93 (1.93), respectively. The PSQ-total, PSQ-minor, and PSQ-moderate of the Korean version showed very good internal consistencies determined by the Cronbach's α of 0.926, 0.869, and 0.877, respectively. For convergent validity, the PSQ scores of the Korean version showed significant correlations with pain catastrophizing scale (PCS) (r = 0.377, P = 0.002; r = 0.365, P = 0.003; r = 0.362, P = 0.003 for PSQ-total, PSQ-minor, and PSQ-moderate of the Korean version, respectively). For test-retest reliability, the intraclass correlation coefficients were 0.782 for PSQ-total, 0.752 for PSQ-minor, and 0.793 for PSQ-moderate. In conclusion, the validated Korean version of PSQ is a transculturally equivalent, reliable, and valid tool to assess individual pain sensitivity. © 2013 World Institute of Pain.

  17. The IRIDICA BAC BSI Assay: Rapid, Sensitive and Culture-Independent Identification of Bacteria and Candida in Blood.

    Directory of Open Access Journals (Sweden)

    David Metzgar

    Full Text Available Bloodstream infection (BSI and sepsis are rising in incidence throughout the developed world. The spread of multi-drug resistant organisms presents increasing challenges to treatment. Surviving BSI is dependent on rapid and accurate identification of causal organisms, and timely application of appropriate antibiotics. Current culture-based methods used to detect and identify agents of BSI are often too slow to impact early therapy and may fail to detect relevant organisms in many positive cases. Existing methods for direct molecular detection of microbial DNA in blood are limited in either sensitivity (likely the result of small sample volumes or in breadth of coverage, often because the PCR primers and probes used target only a few specific pathogens. There is a clear unmet need for a sensitive molecular assay capable of identifying the diverse bacteria and yeast associated with BSI directly from uncultured whole blood samples. We have developed a method of extracting DNA from larger volumes of whole blood (5 ml per sample, amplifying multiple widely conserved bacterial and fungal genes using a mismatch- and background-tolerant PCR chemistry, and identifying hundreds of diverse organisms from the amplified fragments on the basis of species-specific genetic signatures using electrospray ionization mass spectrometry (PCR/ESI-MS. We describe the analytical characteristics of the IRIDICA BAC BSI Assay and compare its pre-clinical performance to current standard-of-care methods in a collection of prospectively collected blood specimens from patients with symptoms of sepsis. The assay generated matching results in 80% of culture-positive cases (86% when common contaminants were excluded from the analysis, and twice the total number of positive detections. The described method is capable of providing organism identifications directly from uncultured blood in less than 8 hours.The IRIDICA BAC BSI Assay is not available in the United States.

  18. Near-term hybrid vehicle program, phase 1. Appendix D: Sensitivity analysis resport

    Science.gov (United States)

    1979-01-01

    Parametric analyses, using a hybrid vehicle synthesis and economics program (HYVELD) are described investigating the sensitivity of hybrid vehicle cost, fuel usage, utility, and marketability to changes in travel statistics, energy costs, vehicle lifetime and maintenance, owner use patterns, internal combustion engine (ICE) reference vehicle fuel economy, and drive-line component costs and type. The lowest initial cost of the hybrid vehicle would be $1200 to $1500 higher than that of the conventional vehicle. For nominal energy costs ($1.00/gal for gasoline and 4.2 cents/kWh for electricity), the ownership cost of the hybrid vehicle is projected to be 0.5 to 1.0 cents/mi less than the conventional ICE vehicle. To attain this ownership cost differential, the lifetime of the hybrid vehicle must be extended to 12 years and its maintenance cost reduced by 25 percent compared with the conventional vehicle. The ownership cost advantage of the hybrid vehicle increases rapidly as the price of fuel increases from $1 to $2/gal.

  19. Breast and cervical cancer screening among Latinas attending culturally specific educational programs.

    Science.gov (United States)

    Jandorf, Lina; Bursac, Zoran; Pulley, Leavonne; Trevino, Michelle; Castillo, Anabella; Erwin, Deborah O

    2008-01-01

    Latinas in the United States have higher morbidity and mortality rates for breast and cervical cancers (compared with non-Latina Whites), often due to lower screening rates. A community-based participatory research (CBPR) approach could help to improve screening rates by creating a culturally customized educational program for Latino men and women addressing low knowledge, gender roles, and spirituality. This study was designed to assess the effectiveness of a culturally customized program (Esperanza y Vida [Hope and Life]) in increasing breast and cervical cancer screening among Latinas, and to examine how screening rates related to changes in cancer knowledge, differences in ethnic origins, and geographic location. Participants were recruited to attend either a breast and cervical (intervention) or diabetes (control) education program, within a randomized plan. Sixty-nine programs (44 intervention; 25 control) were conducted in Arkansas (AR; n = 39) and New York City (NYC; n = 30) with a total of 847 Latino men and women. Telephone follow-up data were collected on 49% of the women who consented to being contacted 2 months postintervention. At the 2-month follow-up call, screening rates were significantly higher for the intervention versus the control group for clinical breast examination (CBE; 48% vs. 31%; adjusted odds ratio [aOR], 2.2; 95% confidence interval [CI], 1.1-4.2), breast self-examination (45% vs. 27%; aOR, 2.3; 95% CI, 1.1-5.0), and Pap testing (51% vs. 30%; aOR, 3.9; 95% CI, 1.1-14.1), but not for mammography (67% vs. 58%; aOR, 0.7; 95% CI, 0.1-3.6). The aORs accounted for the significant effects of study site (AR vs. NYC) and marital status. Esperanza y Vida has the potential to reduce health disparities in breast and cervical cancer morbidity and mortality rates through increasing cancer screening and thereby increasing early detection.

  20. The cultural construction of interdisciplinarity: Doctoral student socialization in an interdisciplinary neuroscience program

    Science.gov (United States)

    Holley, Karri A.

    Using the methodologies of individual and group interviews, observation, and document analysis, this dissertation examines the experiences of doctoral students enrolled in an interdisciplinary neuroscience program. A framework drawn from theories of organizational socialization is employed to understand the influence of an interdisciplinary program on doctoral student socialization. While abundant previous literature exists in regards to the socialization of doctoral students, such literature largely concentrates the disciplinary experience. The escalating import of globalization and shifting fiscal realities place new demands on Ph.D. programs and doctoral students to work as part of collaborative research teams, produce interdisciplinary knowledge, and integrate theory and practice. The increasing influence of such factors requires a new focus on interdisciplinarity and the changing Ph.D. The goal of this dissertation is to expand the existing framework of socialization by documenting the influence of such obstacles on knowledge acquisition, identity development, and professional investment. This study focuses on how interdisciplinary identities are constructed by doctoral students through individual interaction with the social environment and cultural context. Particular attention is given to the structural and cultural obstacles that doctoral students must negotiate as they navigate an interdisciplinary program. The study expands on the previous literature regarding doctoral student socialization by focusing on identity development, specifically a student's symbolic identity as a neuroscientist, a student's disciplinary identity (related to her professional background and undergraduate experiences), and a multi-disciplinary identity that allows for connections across disciplinary boundaries. In contrast to the traditional concepts of identity which focus on boundaries and differences as an inherent part of self-definition, the structure of identity advanced

  1. [EVALUATION OF THE HUMAN SENSITIVITY TO SMALLPOX VIRUS BY THE PRIMARY CULTURES OF THE MONOCYTE-MACROPHAGES].

    Science.gov (United States)

    Zamedyanskaya, A S; Titova, K A; Sergeev, Al A; Kabanov, A S; Bulychev, L E; Sergeev, Ar A; Galakhova, D O; Nesterov, A E; Nosareva, O V; Shishkina, L N; Taranov, O S; Omigov, V V; Agafonov, A P; Sergeev, A N

    2016-01-01

    Studies of the primary cultures of granulocytes, mononuclear, and monocyte-macrophage cells derived from human blood were performed using variola virus (VARV) in the doses of 0.001-0.021 PFU/cell (plaques-forming units per cell). Positive dynamics of the virus accumulation was observed only in the monocyte-macrophages with maximum values of virus concentration (5.0-5.5 Ig PFU/ml) mainly within six days after the infection. The fact of VARV replication in the monocyte-macrophages was confirmed by the data of electron microscopy. At the same time, virus vaccines when tested in doses 3.3 and 4.2 Ig PFU/ml did not show the ability to reproduce in these human cells. The people sensitivity to VARV as assessed from the data obtained on human monocyte-macrophages corresponded to -1 PFU (taking into account the smooth interaction of the virus in the body to the cells of this type), which is consistent to previously found theoretical data on the virus sensitivity. The human susceptibility to VARV assessed experimentally can be used to predict the adequacy of developed smallpox models (in vivo) based on susceptible animals. This is necessary for reliable assessment of the efficiency of development of drugs for treatment and prophylaxis of the smallpox.

  2. A Comparative Cross-Cultural Examination of Community Art Education Programs in South Korea and the United States

    Science.gov (United States)

    Shin, Ryan; Kim, Junghee

    2014-01-01

    The authors conducted comparative cross-cultural research to examine a select group of the available and more noteworthy art education organizations and their programs after observing significant differences in the community art education programs offered in Tucson, Arizona, and Anyang, South Korea. The study reports several major differences…

  3. Naming Their World in a Culturally Responsive Space: Experiences of Hmong Adolescents in an After-School Theatre Program

    Science.gov (United States)

    Ngo, Bic

    2017-01-01

    This article draws on ethnographic research of a youth theatre program within a Hmong arts organization to explore the ways in which a culturally responsive program nurtured critical consciousness among Hmong immigrant youth. Hmong youth "named" struggles with stereotypes and acculturation expectations, and constructed positive ethnic…

  4. Cultural competency in peer-run programs: results of a web survey and implications for future practice.

    Science.gov (United States)

    Jonikas, Jessica A; Kiosk, Stephen; Grey, Dennis D; Hamilton, Marie M; McNulty, James; Cook, Judith A

    2010-01-01

    The study explored perceptions of adults with psychiatric disabilities regarding cultural competency of peer-run mental health support groups and programs. Web survey respondents were recruited via mental health list-servs, web sites, newsletters, emails, and word of mouth. A total of 527 peers were surveyed about cultural competency barriers facing peer-run programs; common reasons for not using peer services; and strategies to engage diverse communities. Both multicultural and Caucasian respondents agreed that lack of funding and staff education about diversity were barriers to cultural competency in peer programs. Multicultural respondents were more likely than whites to feel that both the recognition of the need for and interest in attending cultural competency training is lacking in peer programs, as well as information about the diverse composition of peer program memberships. Among those who had never participated in peer support, people of color were more likely than whites to endorse feeling they would not belong and believing their languages would not be spoken in peer programs. Whites, on the other hand, were more likely to cite a preference for professional over peer support, while nearly half of both groups indicated that the main reason for non-attendance is a lack of knowledge about peer programs. Qualitative results highlighted successful outreach and engagement strategies. Study findings informed development of a cultural competency tool that was pilot-tested among peer-run programs. Given the importance of peer support in recovery, these findings suggest the need for additional research on cultural competency in peer programs.

  5. Mehar Methods for Fuzzy Optimal Solution and Sensitivity Analysis of Fuzzy Linear Programming with Symmetric Trapezoidal Fuzzy Numbers

    Directory of Open Access Journals (Sweden)

    Sukhpreet Kaur Sidhu

    2014-01-01

    Full Text Available The drawbacks of the existing methods to obtain the fuzzy optimal solution of such linear programming problems, in which coefficients of the constraints are represented by real numbers and all the other parameters as well as variables are represented by symmetric trapezoidal fuzzy numbers, are pointed out, and to resolve these drawbacks, a new method (named as Mehar method is proposed for the same linear programming problems. Also, with the help of proposed Mehar method, a new method, much easy as compared to the existing methods, is proposed to deal with the sensitivity analysis of the same type of linear programming problems.

  6. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, M.J.; Brooks, R.D.; Sassaman, K.E.; Crass, D.C. [and others

    1995-10-01

    The Savannah River Archaeological Research Program (SRARP) continued through FY95 with the United States Department of Energy to fulfill a threefold mission of cultural resource management, research, and public education at the Savannah River Site. Over 2,300 acres of land on the SRS came under cultural resources review in FY95. This activity entailed 30 field surveys, resulting in the recording of 86 new sites. Twenty-two existing sites within survey tract boundaries were revisited to update site file records. Research conducted by SRARP was reported in 11 papers and monographs published during FY95. SRARP staff also presented research results in 18 papers at professional meetings. Field research included several testing programs, excavations, and remote sensing at area sites, as well as data collection abroad. Seven grants were acquired by SRARP staff to support off-site research. In the area of heritage education, the SRARP expanded its activities in FY95 with a full schedule of classroom education, public outreach, and on-site tours. Volunteer excavations at the Tinker Creek site were continued with the Augusta Archaeological Society and other avocational groups, and other off-site excavations provided a variety of opportunities for field experience. Some 80 presentations, displays and tours were provided for schools, historical societies, civic groups, and environmental and historical awareness day celebrations. Additionally, SRARP staff taught four anthropology courses at area colleges.

  7. A Language Exchange Program: Sustainability Innovation in Language and Culture Engagement

    Directory of Open Access Journals (Sweden)

    Trinidad Fernández

    2014-04-01

    Full Text Available Spanish Educational Laws over the past years have been promoting the widespread use of English as the vehicle for teaching and learning in most curricular subjects. This trend is evincing new needs especially among higher education students. Consequently, Spanish Universities are looking for ways to provide international training involving global partnerships. The Polytechnic University of Madrid, Spain (UPM, and the University of British Columbia, Okanagan, Canada (UBCO have come together to offer opportunities for international collaboration and learning, thus facilitating virtual encounters among Spanish and Canadian students. The Language Exchange Program between the UPM and UBCO acts as a model for sustainability innovation in language and culture engagement as the students can interact with native speakers in communication tasks. This interdisciplinary initiative supports the latest methodological principles observed in the Common European Framework for Languages [1], such as autonomous and life-long learning, self-assessment and peer-assessment as well as the incorporation of new technologies to the learning process. Additionally the 'virtual' mobility is provided at no extra cost. This article presents the preliminary results of two virtual exchange programs that have been offering varied forms of study which are venue-independent, promoting collaborative work and cultural exchange.

  8. A 12 week aerobic exercise program improves fitness, hepatic insulin sensitivity and glucose metabolism in obese Hispanic adolescents

    Science.gov (United States)

    The rise in obesity related morbidity in children and adolescents requires urgent prevention and treatment strategies. Strictly controlled exercise programs might be useful tools to improve insulin sensitivity and glucose kinetics. Our objective was to test the hypothesis that a 12-wk aerobic exerci...

  9. Cultured mast cells from asthmatic patients and controls respond with similar sensitivity to recombinant Der P2 induced, IgE-mediated activation

    DEFF Research Database (Denmark)

    Krohn, Inge Jacoba Maria Kortekaas; Sverrild, Asger; Lund, Gitte;

    2013-01-01

    The function of cultured mast cells may depend on genetic or environmental influence on the stem cell donor. This study investigates whether asthma or atopy in the donor influenced the growth and sensitivity of mast cells cultured from patients with asthma and healthy controls under identical...... conditions. Mast cells were cultured from peripheral blood from twelve patients with an objectively confirmed asthma diagnosis and eight healthy subjects. During the last 2 weeks of culture, mast cells were incubated with IL-4 and 80 kU/l recombinant human IgE containing two clones (7% + 7%) specific...... for mite allergen Der p2. The sensitivity of IgE-mediated activation of mast cells was investigated as FcεRI-mediated upregulation of CD63. Ten subjects were atopic, defined as a positive skin prick test (>3 mm) to at least one of ten common allergens. After activation with recombinant Der p2, the maximum...

  10. Tapping into the Culture of Homelessness.

    Science.gov (United States)

    Davis, Ruth E.

    1996-01-01

    Findings of a qualitative study of three health and human services agencies determined that strategies of survival inherent in the culture of homelessness are rarely considered by those agencies in providing services to homeless people. Programs should develop cultural sensitivity and use a cultural perspective in planning. (JOW)

  11. Urine culture

    Science.gov (United States)

    Culture and sensitivity - urine ... when urinating. You also may have a urine culture after you have been treated for an infection. ... when bacteria or yeast are found in the culture. This likely means that you have a urinary ...

  12. Program of institutionalism scientific research: «endogenization of institutions» and economic culture

    Directory of Open Access Journals (Sweden)

    Yu.V. Ushchapovskyy

    2015-03-01

    Full Text Available The formation of the institutionalism scientific research uniform program (the paradigm is hindered by the absence of the unity concerning the source of institutional restrictions for an individual between the supporters of different directions in the institutionalism. They look for the ways of «institutions endogenization» through defining the place of economic culture in forming institutional environment and the uniform paradigm of modern institutionalism. The author emphasizes the imperfection of neoinstitutionalism conception that focuses on exogenous origin of institutional restrictions for an individual. Making distinction between institutions and customs, they explain institutions as different standards and rules of behavior. Directing the explanation from individuals to institutions they recognize the ontological priority of an individual. A certain institutionally unbiased «natural state» is supposed, provided that institutions appear only as a result of interaction between individuals. Since not only institutions restrict the individuals’ interests but individuals form institutional restrictions as well, the author thinks that the conception of «institution» should take into account its exogenous and endogenous nature. The idea of «institutions endogenization» by D.North, also supported by the author of the article, is the closest to this conception realization. Such explanation of «institution» should provide axiological and attitudinal aspects of scientific knowledge; it should make a person not only a blind doer, but also an active participant of evolutionary changes in economic life. A certain institutional structure is always made up of a set of formal rules and informal restrictions, which are indivisible and specific of every culture. The author defines the economy institutional structure as the system of institutions that through organizing everyday life decreases the uncertainty of individuals’ interaction

  13. Gulf-Wide Information System, Environmental Sensitivity Index National Heritage Program Database, Geographic NAD83, LDWF (2001) [esi_nhp_LDWF_2001

    Data.gov (United States)

    Louisiana Geographic Information Center — This data set contains sensitive biological resource data developed from the Louisiana National Heritage Program (NHP) database for coastal Louisiana. Vector...

  14. Culture-specific programs for children and adults from minority groups who have asthma.

    Science.gov (United States)

    McCallum, Gabrielle B; Morris, Peter S; Brown, Ngiare; Chang, Anne B

    2017-08-22

    studies ranged from very low to low. For our primary outcome (asthma exacerbations during follow-up), the quality of evidence was low for all outcomes. In adults, use of a culture-specific programme, compared to generic programmes or usual care did not significantly reduce the number of participants from two studies with 294 participants for: exacerbations with one or more exacerbations during follow-up (odds ratio (OR) 0.80, 95% confidence interval (CI) 0.50 to 1.26), hospitalisations over 12 months (OR 0.83, 95% CI 0.31 to 2.22) and exacerbations requiring oral corticosteroids (OR 0.97, 95% CI 0.55 to 1.73). However, use of a culture-specific programme, improved asthma quality of life scores in 280 adults from two studies (mean difference (MD) 0.26, 95% CI 0.17 to 0.36) (although the MD was less then the minimal important difference for the score). In children, use of a culture-specific programme was superior to generic programmes or usual care in reducing severe asthma exacerbations requiring hospitalisation in two studies with 305 children (rate ratio 0.48, 95% CI 0.24 to 0.95), asthma control in one study with 62 children and QoL in three studies with 213 children, but not for the number of exacerbations during follow-up (OR 1.55, 95% CI 0.66 to 3.66) or the number of exacerbations (MD 0.18, 95% CI -0.25 to 0.62) among 100 children from two studies. The available evidence showed that culture-specific education programmes for adults and children from minority groups are likely effective in improving asthma-related outcomes. This review was limited by few studies and evidence of very low to low quality. Not all asthma-related outcomes improved with culture-specific programs for both adults and children. Nevertheless, while modified culture-specific education programs are usually more time intensive, the findings of this review suggest using culture-specific asthma education programmes for children and adults from minority groups. However, more robust RCTs are needed to

  15. The Implementation and Evaluation of Health Promotion Services and Programs to Improve Cultural Competency: A Systematic Scoping Review.

    Science.gov (United States)

    Jongen, Crystal Sky; McCalman, Janya; Bainbridge, Roxanne Gwendalyn

    2017-01-01

    Cultural competency is a multifaceted intervention approach, which needs to be implemented at various levels of health-care systems to improve quality of care for culturally and ethnically diverse populations. One level of health care where cultural competency is required is in the provision of health promotion services and programs targeted to diverse patient groups who experience health-care and health inequalities. To inform the implementation and evaluation of health promotion programs and services to improve cultural competency, research must assess both intervention strategies and intervention outcomes. This scoping review was completed as part of a larger systematic literature search conducted on evaluations of cultural competence interventions in health care in Canada, the United States, Australia, and New Zealand. Seventeen peer-reviewed databases, 13 websites and clearinghouses, and 11 literature reviews were searched. Overall, 64 studies on cultural competency interventions were found, with 22 being health promotion programs and services. A process of thematic analysis was utilized to identify key intervention strategies and outcomes reported in the literature. The review identified three overarching strategies utilized in health promotion services and programs to improve cultural competency: community-focused strategies, culturally focused strategies, and language-focused strategies. Studies took different approaches to delivering culturally competent health interventions, with the majority incorporating multiple strategies from each overarching category. There were various intermediate health-care and health outcomes reported across the included studies. Most commonly reported were positive reports of patient satisfaction, patient/participant service access, and program/study retention rates. The health outcome results indicate positive potential of health promotion services and programs to improve cultural competency to impact cardiovascular disease

  16. Exploring the parent agency through a culturally relevant and inclusive science program

    Science.gov (United States)

    Hagiwara, Sumi

    2002-01-01

    Science education reform calls for the inclusivity of all learners, the same should also apply to immigrant Latino/a parents. The Literacy in Food and the Environment (LIFE) program, a two-year inner-city middle-school science curriculum designed to teach science, nutrition and the environment through investigations of food is analyzed based on quantitative and qualitative data gathered during 1999--2001. A sample of 19 immigrant Latino/a parents participated in 12 workshops and collaborated with teachers in the classroom to implement the curriculum. A quantitative analysis of year one using a pre/post test design measured the impact of the program on the parents' science knowledge, attitude and beliefs about science and participating in their child's science education, and food choices and behavior. Four mothers continued with the program in year two. Qualitative data was gathered to create descriptive case studies. From the data I developed an interpretive discussion based on cross case analysis using a grounded theory method, When compared to a comparison group (n = 13), quantitative results showed significantly higher outcomes for science knowledge on the topics of energy flow (65% intervention vs, 37% control, p culture and language in positioning self in science and in school, (3) the mothers' experience as socially transformative. By engaging parents inside the classroom with science taught through food, parents' knowledge, attitudes and beliefs around science improved, as they developed a sense of agency transforming their role from parent to educator.

  17. Introduction of culturally sensitive HIV prevention in the context of female initiation rites: an applied anthropological approach in Mozambique.

    Science.gov (United States)

    Kotanyi, Sophie; Krings-Ney, Brigitte

    2009-12-01

    In Mozambique, initiation rites represent the most appropriate socio-cultural context for dealing with sexuality for a large part of the population. As the group most vulnerable to HIV exposure, HIV-prevention counselling could be ideally introduced to young women during initiation rites. This article demonstrates how interventions can take advantage of the positive aspects of this tradition. We discuss local notions of social 'contamination' versus biological 'contamination,' and we present a culturally sensitive communication strategy to bridge the divergent paradigms around AIDS-similar symptoms. Because of the emotional importance of the initiation rites, the suggested approach goes far beyond cognitive knowledge. After training, the godmothers in initiation rites became highly motivated to teach novice girls about HIV prevention and they trained other elderly women as well. Thus, the initiation rites turned into a process of empowerment for women in their own communities. A central agenda of the female initiation rites in Mozambique is to inculcate respect towards ancestors, elders, authorities and others; however, this respectful attitude between genders and between generations is disappearing due to factors like warfare and the cash economy. HIV-prevention counselling may be successfully introduced into initiation rites because of the unconscious, emotional impact of the process on the initiates' behaviour. Other studies have shown that cognitive knowledge is not enough to lead to behavioural changes. Without changing the traditional initiation rites for females, which in Mozambique includes no genital cutting, a complementary approach introduces HIV-prevention counselling during ritual counselling moments, thereby motivating godmothers and novice girls and young women to be more aware and take precautions to prevent HIV infection.

  18. Improving Culturally Appropriate Care Using a Community-Based Participatory Research Approach: Evaluation of a Multicomponent Cultural Competency Training Program, Arkansas, 2015–2016

    Science.gov (United States)

    Long, Christopher R.; Rowland, Brett; Moore, Sarah; Wilmoth, Ralph; Ayers, Britni

    2017-01-01

    Introduction The United States continues to become more racially and ethnically diverse, and racial/ethnic minority communities encounter sociocultural barriers to quality health care, including implicit racial/ethnic bias among health care providers. In response, health care organizations are developing and implementing cultural competency curricula. Using a community-based participatory research (CBPR) approach, we developed and evaluated a cultural competency training program to improve the delivery of culturally appropriate care in Marshallese and Hispanic communities. Methods We used a mixed-methods evaluation approach based on the Kirkpatrick model of training evaluation. We collected quantitative evaluation data immediately after each training session (March 19, 2015–November 30, 2016) and qualitative data about implementation at 2 points: immediately after each session and 6 months after training. Individuals and organizational units provided qualitative data. Results We delivered 1,250 units of in-person training at 25 organizations. Participants reported high levels of changes in knowledge (91.2%), competence (86.6%), and performance (87.2%) as a result of the cultural competency training. Organizations reported making policy and environmental changes. Conclusion Initial outcomes demonstrate the value of developing and implementing cultural competency training programs using a CBPR approach. Additional research is needed to determine the effect on long-term patient outcomes. PMID:28771402

  19. Attending to Communication and Patterns of Interaction: Culturally Sensitive Mental Health Care for Groups of Urban, Ethnically Diverse, Impoverished, and Underserved Women.

    Science.gov (United States)

    Molewyk Doornbos, Mary; Zandee, Gail Landheer; DeGroot, Joleen

    2014-07-01

    The United States is ethnically diverse. This diversity presents challenges to nurses, who, without empirical evidence to design culturally congruent interventions, may contribute to mental health care disparities. Using Leininger's theory of culture care diversity and universality, this study documented communication and interaction patterns of ethnically diverse, urban, impoverished, and underserved women. Using a community-based participatory research framework, 61 Black, Hispanic, and White women participated in focus groups around their experiences with anxiety/depression. Researchers recorded verbal communication, nonverbal behavior, and patterns of interaction. The women's communication and interaction patterns gave evidence of three themes that were evident across all focus groups and five subthemes that emerged along ethnic lines. The results suggest cultural universalities and cultural uniquenesses relative to the communication and interaction patterns of urban, ethnically diverse, impoverished, and underserved women that may assist in the design of culturally sensitive mental health care. © The Author(s) 2014.

  20. Quality Initiative Program in Its Sixth Year: Has It Become Part of Our Radiology Culture?

    Science.gov (United States)

    Ritchie, Heather; Kielar, Ania Z; Hill, Fraser; O'Sullivan, Joseph P

    2017-08-01

    The study sought to determine if the Quality Initiative Program (QUIP) has become part of the radiology culture at our institution. After Research Ethics approval, QUIPs from January 2009 to December 2014 were assessed. We evaluated the response rates of radiologists receiving QUIPs to ensure they reviewed them. We performed a survey of radiologists and trainees to gain feedback regarding their perception of QUIPs in February 2014 and in June 2015. Response rates of radiologists receiving a QUIP improved, with 76% response rate in 2014 up from 66% in the first year and 42% in the second year. Based on the 2015 survey including radiologists and trainees, 75% agreed that QUIPs were educational, compared with 67% 16 months earlier. Fifty percent of respondents had changed their overall practice of reporting based on feedback from the QUIP in 2015 compared with 32% in 2014. In both surveys, 100% of respondents indicated that QUIPs have not been used against them for any disciplinary measure (or other negatively perceived action). When asked if there was a perceived decrease in stigma felt when a QUIP was received, 71% agreed or were neutral and 28% disagreed. The QUIP is educational to radiologists and trainees, leading to positive changes in clinical practice. The majority accepts this program but there is still a stigma felt when a QUIP is received, particularly among residents. Nevertheless, we feel that QUIP has been integrated into our radiology culture and, hopefully, imminent transition to commercial quality software will be smooth. Copyright © 2016 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

  1. Endangered species and cultural resources program, Naval Petroleum Reserves in California: Annual report FY95

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    In FY95, EG and G Energy Measurements, Inc. (EG and G/EM) continued to support efforts to protect endangered species and cultural resources at the Naval Petroleum Reserves in California (NPRC). These efforts are conducted to ensure NPRC compliance with regulations regarding the protection of listed species and cultural resources on Federal properties. Population monitoring activities are conducted annually for San Joaquin kit foxes, giant kangaroo rats, blunt-nosed leopard lizards, and Hoover`s wooly-star. To mitigate impacts of oil field activities on listed species, 674 preactivity surveys covering approximately 211 hectares (521 acres) were conducted in FY95. EG and G/EM also assisted with mitigating effects from third-party projects, primarily by conducting biological and cultural resource consultations with regulatory agencies. EG and G/EM has conducted an applied habitat reclamation program at NPRC since 1985. In FY95, an evaluation of revegetation rates on reclaimed and non-reclaimed disturbed lands was completed, and the results will be used to direct future habitat reclamation efforts at NPRC. In FY95, reclamation success was monitored on 50 sites reclaimed in 1985. An investigation of factors influencing the distribution and abundance of kit foxes at NPRC was initiated in FY94. Factors being examined include habitat disturbance, topography, grazing, coyote abundance, lagomorph abundance, and shrub density. This investigation continued in FY95 and a manuscript on this topic will be completed in FY96. Also, Eg and G/EM completed collection of field data to evaluate the effects of a well blow-out on plant and animal populations. A final report will be prepared in FY96. Finally, EG and G/EM completed a life table analysis on San Joaquin kit foxes at NPRC.

  2. Use of sensitive, broad-spectrum molecular assays and human airway epithelium cultures for detection of respiratory pathogens.

    Directory of Open Access Journals (Sweden)

    Krzysztof Pyrc

    Full Text Available Rapid and accurate detection and identification of viruses causing respiratory tract infections is important for patient care and disease control. Despite the fact that several assays are available, identification of an etiological agent is not possible in ~30% of patients suffering from respiratory tract diseases. Therefore, the aim of the current study was to develop a diagnostic set for the detection of respiratory viruses with sensitivity as low as 1-10 copies per reaction. Evaluation of the assay using a training clinical sample set showed that viral nucleic acids were identified in ~76% of cases. To improve assay performance and facilitate the identification of novel species or emerging strains, cultures of fully differentiated human airway epithelium were used to pre-amplify infectious viruses. This additional step resulted in the detection of pathogens in all samples tested. Based on these results it can be hypothesized that the lack of an etiological agent in some clinical samples, both reported previously and observed in the present study, may result not only from the presence of unknown viral species, but also from imperfections in the detection methods used.

  3. Use of Sensitive, Broad-Spectrum Molecular Assays and Human Airway Epithelium Cultures for Detection of Respiratory Pathogens

    Science.gov (United States)

    Wojcik, Krzysztof; Gawron, Katarzyna; Zeglen, Slawomir; Karolak, Wojciech; Wojarski, Jacek; Ochman, Marek; Hubalewska-Mazgaj, Magdalena; Bochenek, Grazyna; Sanak, Marek; Zembala, Marian; Szczeklik, Andrzej; Potempa, Jan

    2012-01-01

    Rapid and accurate detection and identification of viruses causing respiratory tract infections is important for patient care and disease control. Despite the fact that several assays are available, identification of an etiological agent is not possible in ∼30% of patients suffering from respiratory tract diseases. Therefore, the aim of the current study was to develop a diagnostic set for the detection of respiratory viruses with sensitivity as low as 1–10 copies per reaction. Evaluation of the assay using a training clinical sample set showed that viral nucleic acids were identified in ∼76% of cases. To improve assay performance and facilitate the identification of novel species or emerging strains, cultures of fully differentiated human airway epithelium were used to pre-amplify infectious viruses. This additional step resulted in the detection of pathogens in all samples tested. Based on these results it can be hypothesized that the lack of an etiological agent in some clinical samples, both reported previously and observed in the present study, may result not only from the presence of unknown viral species, but also from imperfections in the detection methods used. PMID:22403676

  4. Experience of using an interdisciplinary task force to develop a culturally sensitive multipronged tool to improve stroke outcomes in Nigeria

    Directory of Open Access Journals (Sweden)

    Oyedunni S. Arulogun

    2016-09-01

    Full Text Available The burden of stroke is on the rise in Nigeria. A multi-faceted strategy is essential for reducing this growing burden and includes promoting medication adherence, optimizing traditional biomarker risk targets (blood pressure, cholesterol and encouraging beneficial lifestyle practices. Successful implementation of this strategy is challenged by inadequate patient health literacy, limited patient/medical system resources, and lack of a coordinated interdisciplinary treatment approach. Moreover, the few interventions developed to improve medical care in Nigeria have generally been aimed at physicians (primarily and nurses (secondarily with minimal input from other key health care providers, and limited contributions from patients, caregivers, and the community itself. The Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THRIVES study is assessing the efficacy of a culturally sensitive multidimensional intervention for controlling blood pressure in recent stroke survivors. A key component of the intervention development process was the constitution of a project task force comprising various healthcare providers and administrators. This paper describes the unique experience in Sub-Saharan Africa of utilizing of an interdisciplinary Task force to facilitate the development of the multipronged behavioral intervention aimed at enhancing stroke outcomes in a low-middle income country.

  5. Blood culture gram stain, acridine orange stain and direct sensitivity-based antimicrobial therapy of bloodstream infection in patients with trauma

    Directory of Open Access Journals (Sweden)

    Behera B

    2010-01-01

    Full Text Available Purpose: The purpose of this study was to ascertain if the simple practice of Gram stain, acridine orange stain and direct sensitivity determination of positive blood culture bottles could be used to guide early and appropriate treatment in trauma patients with clinical suspicion of sepsis. The study also aimed to evaluate the error in interpreting antimicrobial sensitivity by direct method when compared to standard method and find out if specific antibiotic-organism combination had more discrepancies. Findings from consecutive episodes of blood stream infection at an Apex Trauma centre over a 12-month period are summarized. Materials and Methods: A total of 509 consecutive positive blood cultures were subjected to Gram staining. AO staining was done in BacT/ALERT-positive Gram-stain negative blood cultures. Direct sensitivity was performed from 369 blood culture broths, showing single type of growth in Gram and acridine orange staining. Results of direct sensitivity were compared to conventional sensitivity for errors. Results: No ′very major′ discrepancy was found in this study. About 5.2 and 1.8% minor error rates were noted in gram-positive and gram-negative bacteria, respectively, while comparing the two methods. Most of the discrepancies in gram-negative bacteria were noted in β lactam - β lactamase inhibitor combinations. Direct sensitivity testing was not reliable for reporting of methicillin and vancomycin resistance in Staphylococci. Conclusions: Gram stain result together with direct sensitivity testing is required for optimizing initial antimicrobial therapy in trauma patients with clinical suspicion of sepsis. Gram staining and AO staining proved particularly helpful in the early detection of candidaemia.

  6. Analyzing the influence of admissions criteria and cultural norms on success in an international dental studies program.

    Science.gov (United States)

    Itaya, Lisa E; Chambers, David W; King, Patricia A

    2008-03-01

    This study determines the extent to which admissions criteria and cultural norms predict the success of a foreign-trained dentist in a United States dental educational program. Correlation and regression tests were applied to an eleven-year period from 1994 to 2004 of retrospective admissions data for 144 International Dental Studies Program students. Five cultural norms were derived from the collective cultural dimensions of a scholarly work of validated multinational surveys by Geert Hofstede. These five cultural norms are Power Distance (degree of inequality between "haves" and "have-nots" in a culture); Individualism (support for independent or group behavior); Long-Term View (deferred gratification versus quick results/rewards); Masculinity (emphasis on performance/outcomes versus socialization); and Uncertainty Avoidance (ability to cope with an uncertain future). Hofstede's calculated country scores on these cultural dimensions applied to the students' countries of education and their influence on students' academic performance were assessed by correlation and regression analyses. Results showed that the TOEFL and National Board Part I examinations and the cultural norm of Long-Term View were the most positive predictors of grade point averages. The other four cultural norms studied were not predictors of success. Those who applied to the program more than once before being accepted did less well in the program, yet "less well" might have meant that they graduated with a 3.0 instead of a 3.5 GPA. Generally speaking, the more recent the graduated class, the higher the ending GPA has been. Admissions committees should determine if they want to invest the resources required to implement a multitude of admissions predictors to find the best of the qualified applicants.

  7. cultural

    Directory of Open Access Journals (Sweden)

    Irene Kreutz

    2006-01-01

    Full Text Available Es un estudio cualitativo que adoptó como referencial teorico-motodológico la antropología y la etnografía. Presenta las experiencias vivenciadas por mujeres de una comunidad en el proceso salud-enfermedad, con el objetivo de comprender los determinantes sócio-culturales e históricos de las prácticas de prevención y tratamiento adoptados por el grupo cultural por medio de la entrevista semi-estructurada. Los temas que emergieron fueron: la relación entre la alimentación y lo proceso salud-enfermedad, las relaciones con el sistema de salud oficial y el proceso salud-enfermedad y lo sobrenatural. Los dados revelaron que los moradores de la comunidad investigada tienen un modo particular de explicar sus procedimientos terapéuticos. Consideramos que es papel de los profesionales de la salud en sus prácticas, la adopción de abordajes o enfoques que consideren al individuo en su dimensión sócio-cultural e histórica, considerando la enorme diversidad cultural en nuestro país.

  8. Abundance and diversity of culturable Pseudomonas constitute sensitive indicators for adverse long-term copper impacts in soil

    DEFF Research Database (Denmark)

    Thorsen, Maja Kristine; Brandt, Kristian Koefoed; Nybroe, Ole

    2013-01-01

    heterotrophic bacteria. This indicates that the Pseudomonas population is not resilient towards copper stress and that culturable Pseudomonas spp. comprise sensitive bio-indicators of adverse copper impacts in contaminated soils. Further this study shows that copper exposure decreases bacterial diversity...

  9. Rapid antibiotic sensitivity testing and trimethoprim-mediated filamentation of clinical isolates of the Enterobacteriaceae assayed on a novel porous culture support

    NARCIS (Netherlands)

    Ingham, C.J.; Ende, van den M.; Wever, P.C.; Schneeberger, P.M.

    2006-01-01

    A porous inorganic material (Anopore) was employed as a microbial culture and microcolony imaging support. Rapid Anopore-based antibiotic sensitivity testing (AST) methods were developed to assess the growth of clinical isolates, with the primary focus on testing the response of the Enterobacteriace

  10. Promoting social-emotional learning in adolescent Latino ELLs: a study of the culturally adapted Strong Teens program.

    Science.gov (United States)

    Castro-Olivo, Sara M

    2014-12-01

    The current study evaluated the effects of the culturally adapted Jóvenes Fuertes (Strong Teens) Social-Emotional Learning (SEL) program on the social-emotional outcomes of Latino English language learners (ELLs). A quasi-experimental design with random assignment by classrooms was used to assess the intervention's effects on students' knowledge of SEL and resiliency. A sample of 102 Spanish-dominant Latino ELLs enrolled in middle or high school participated in this study. The results indicated significant intervention effects on SEL knowledge and social-emotional resiliency. The findings are discussed in terms of their implications for preventive, culturally responsive SEL programs in school settings.

  11. Increasing Cultural And Linguistic Diversity In Deaf Education Teacher Preparation Programs.

    Science.gov (United States)

    Cannon, Joanna E; Luckner, John L

    2016-01-01

    As the field of education of the d/Deaf and hard of hearing (d/Dhh) continues to diversify, postsecondary institutions must pay close attention not only to the changing needs of d/Dhh students but to the practitioners they are preparing to serve this population. Students who are d/Dhh and come from homes where a language other than English or American Sign Language is used--d/Dhh Multilingual Learners (DMLs)--constitute 19.4%-35.0% of the d/Dhh student population (Gallaudet Research Institute, 2013). In the present article, part of a special American Annals of the Deaf issue on DMLs, the authors review demographic trends, examine the theory behind teacher effectiveness and culturally responsive teaching, provide examples from research on effective components of teacher preparation programs and discuss how they align with the field's certification standards, and recommend practices for programs and teachers to meet these standards within the field's ever-changing landscape.

  12. Endangered species and cultural resources program, Naval Petroleum Reserves in California, annual report FY97

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    The Naval Petroleum Reserves in California (NPRC) are oil fields administered by the DOE in the southern San Joaquin Valley of California. Four federally endangered animal species and one federally threatened plant species are known to occur on NPRC: San Joaquin kit fox (Vulpes macrotis mutica), blunt-nosed leopard lizard (Gambelia silus), giant kangaroo rat (Dipodomys ingens), Tipton kangaroo rat (Dipodomys nitratoides), and Hoover`s wooly-star (Eriastrum hooveri). All five are protected under the Endangered Species Act (ESA) of 1973. The DOE/NPRC is obliged to determine whether actions taken by their lessees on Naval Petroleum Reserve No. 2 (NPR-2) will have any effects on endangered species or their habitats. The primary objective of the Endangered Species and Cultural Resources Program is to provide NPRC with the scientific expertise necessary for compliance with the ESA, the National Environmental Policy Act (NEPA), and the National Historic Preservation Act (NHPA). The specific objective of this report is to summarize progress, results, and accomplishments of the program during fiscal year 1997 (FY97).

  13. A sensitivity analysis of central flat-plate photovoltaic systems and implications for national photovoltaics program planning

    Science.gov (United States)

    Crosetti, M. R.

    1985-01-01

    The sensitivity of the National Photovoltaic Research Program goals to changes in individual photovoltaic system parameters is explored. Using the relationship between lifetime cost and system performance parameters, tests were made to see how overall photovoltaic system energy costs are affected by changes in the goals set for module cost and efficiency, system component costs and efficiencies, operation and maintenance costs, and indirect costs. The results are presented in tables and figures for easy reference.

  14. Perceptions of the Host Country's Food Culture among Female Immigrants from Africa and Asia: Aspects Relevant for Cultural Sensitivity in Nutrition Communication

    Science.gov (United States)

    Garnweidner, Lisa Maria; Terragni, Laura; Pettersen, Kjell Sverre; Mosdol, Annhild

    2012-01-01

    Objective: To explore how female immigrants from Africa and Asia perceive the host country's food culture, to identify aspects of their original food culture they considered important to preserve, and to describe how they go about preserving them. Design: Qualitative in-depth interviews. Setting: Oslo, Norway. Participants: Twenty one female…

  15. Perceptions of the Host Country's Food Culture among Female Immigrants from Africa and Asia: Aspects Relevant for Cultural Sensitivity in Nutrition Communication

    Science.gov (United States)

    Garnweidner, Lisa Maria; Terragni, Laura; Pettersen, Kjell Sverre; Mosdol, Annhild

    2012-01-01

    Objective: To explore how female immigrants from Africa and Asia perceive the host country's food culture, to identify aspects of their original food culture they considered important to preserve, and to describe how they go about preserving them. Design: Qualitative in-depth interviews. Setting: Oslo, Norway. Participants: Twenty one female…

  16. Differential sensitivity to beta-cell secretagogues in cultured rat pancreatic islets exposed to human interleukin-1 beta.

    Science.gov (United States)

    Eizirik, D L; Sandler, S; Hallberg, A; Bendtzen, K; Sener, A; Malaisse, W J

    1989-08-01

    The early stages of insulin-dependent diabetes mellitus are characterized by a selective inability to secrete insulin in response to glucose, coupled to a better response to nonnutrient secretagogues. The deficient glucose response may be a result of the autoimmune process directed toward the beta-cells. Interleukin-1 (IL-1) has been suggested to be one possible mediator of immunological damage of the beta-cells. In the present study we characterized the sensitivity of beta-cells to different secretagogues after human recombinant IL-1 beta (rIL-1 beta) exposure. Furthermore, experiments were performed to clarify the biochemical mechanisms behind the defective insulin response observed in these islets. Rat pancreatic islets were isolated and kept in tissue culture (medium RPMI-1640 plus 10% calf serum) for 5 days. The islets were subsequently exposed to 60 pM human recombinant IL-1 beta during 48 h in the same culture conditions as above and examined immediately after IL-1 exposure. The rIL-1 beta-treated islets showed a marked reduction of glucose-stimulated insulin release. Stimulation with arginine plus different glucose concentrations, and leucine plus glutamine partially counteracted the rIL-1 beta-induced reduction of insulin release. The activities of the glycolytic enzymes hexokinase, glucokinase, and glyceraldehyde 3-phosphate dehydrogenase, were similar in control and IL-1-exposed islets. Treatment with IL-1 also did not impair the activities of NADH+- and NADPH+-dependent glutamate dehydrogenase, glutamate-aspartate transaminase, glutamate-alanine transaminase, citrate synthase, and NAD+-linked isocitrate dehydrogenase. The oxidation of D-[6-14C]glucose and L-[U-14C]leucine were decreased by 50% in IL-1-treated islets. Furthermore, there was a significant decrease in the ratios of [2-14C]pyruvate oxidation/[1-14C]pyruvate decarboxylation and L-[U-14C]leucine oxidation/L-[1-14C]leucine decarboxylation, indicating that IL-1 decreases the proportion of

  17. Overdiagnosis, sojourn time, and sensitivity in the Copenhagen mammography screening program

    DEFF Research Database (Denmark)

    Olsen, Anne Helene; Agbaje, Olorunsola F; Myles, Jonathan P

    2006-01-01

    The goal of this research was to estimate the overdiagnosis at the first and second screens of the mammography screening program in Copenhagen, Denmark. This study involves a mammography service screening program in Copenhagen, Denmark, with 35,123 women screened at least once. We fit multistate...

  18. An optimisation approach for culturing shear-sensitive dinoflagellate microalgae in bench-scale bubble column photobioreactors.

    Science.gov (United States)

    López-Rosales, L; García-Camacho, F; Sánchez-Mirón, A; Contreras-Gómez, A; Molina-Grima, E

    2015-12-01

    The dinoflagellate Karlodinium veneficum was grown in bubble column photobioreactors and a genetic algorithm-based stochastic search strategy used to find optimal values for the culture parameters gas flow rate, culture height, and nozzle sparger diameter. Cell production, concentration of reactive oxygen species (ROS), membrane fluidity and photosynthetic efficiency were studied throughout the culture period. Gas-flow rates below 0.26Lmin(-1), culture heights over 1.25m and a nozzle diameter of 1.5mm were found to provide the optimal conditions for cell growth, with an increase of 60% in cell production with respect to the control culture. Non-optimal conditions produced a sufficiently high shear stress to negatively affect cell growth and even produce cell death. Cell physiology was also severely affected in stressed cultures. The production of ROS increased by up to 200%, whereas cell membrane fluidity decreased by 60% relative to control cultures. Photosynthetic efficiency decreased concomitantly with membrane fluidity.

  19. Presentaciones escolares. Serie de programas para conmemorar acontecimientos de valor cultural para el mexico americano (School Assembly Presentations. Series of Programs to Commemorate Events of Cultural Value to the Mexican American).

    Science.gov (United States)

    Villarreal, Abelardo; And Others

    This material consists of a series of cultural presentations designed for elementary school assemblies or special programs. The activities are intended to strengthen Mexican-American children's awareness of their cultural heritage. Program scripts, poems, songs, historical narratives and skits are included to illustrate and celebrate Mexican and…

  20. Cross-Age Reading Buddies and Cultural-Sensitive Literature: Student-Centered English Language Instruction in an Ethiopian Budget School

    Science.gov (United States)

    Cianca, Sherri

    2012-01-01

    The Ethiopian government has called for educational improvement, emphasizing the employment of active, student-centered pedagogy. One way of maximizing an interactive learning approach involves blending a cross-age reading buddies program with high-quality, culturally relevant children's literature. Employing descriptive, mixed-method research,…

  1. Cross-Age Reading Buddies and Cultural-Sensitive Literature: Student-Centered English Language Instruction in an Ethiopian Budget School

    Science.gov (United States)

    Cianca, Sherri

    2012-01-01

    The Ethiopian government has called for educational improvement, emphasizing the employment of active, student-centered pedagogy. One way of maximizing an interactive learning approach involves blending a cross-age reading buddies program with high-quality, culturally relevant children's literature. Employing descriptive, mixed-method research,…

  2. Sensitivity analysis of efficient solution in vector MINMAX boolean programming problem

    Directory of Open Access Journals (Sweden)

    Vladimir A. Emelichev

    2002-11-01

    Full Text Available We consider a multiple criterion Boolean programming problem with MINMAX partial criteria. The extreme level of independent perturbations of partial criteria parameters such that efficient (Pareto optimal solution preserves optimality was obtained.

  3. Cultural Adaptation of a Cognitive Behavior Therapy Guided Self-Help Program for Mexican American Women with Binge Eating Disorders

    Science.gov (United States)

    Shea, Munyi; Cachelin, Fary; Uribe, Luz; Striegel, Ruth H.; Thompson, Douglas; Wilson, G. Terence

    2012-01-01

    Data on the compatibility of evidence-based treatment in ethnic minority groups are limited. This study utilized focus group interviews to elicit Mexican American women's (N = 12) feedback on a cognitive behavior therapy guided self-help program for binge eating disorders. Findings revealed 6 themes to be considered during the cultural adaptation…

  4. Building a Graduate Professional Culture: A Case for Student Involvement in Developing and Sustaining an Adult Education Graduate Program.

    Science.gov (United States)

    Crew, Edith; Lewis, John L.

    A proposed approach to the generation of a graduate professional culture is grounded in the planned, systematic involvement of students in developing and sustaining a graduate adult education program. The approach has a conceptual basis in the works of Jahns and Urbano (1986), who presented a framework of developmental stages toward completion of…

  5. Cultural Adaptation of a Cognitive Behavior Therapy Guided Self-Help Program for Mexican American Women with Binge Eating Disorders

    Science.gov (United States)

    Shea, Munyi; Cachelin, Fary; Uribe, Luz; Striegel, Ruth H.; Thompson, Douglas; Wilson, G. Terence

    2012-01-01

    Data on the compatibility of evidence-based treatment in ethnic minority groups are limited. This study utilized focus group interviews to elicit Mexican American women's (N = 12) feedback on a cognitive behavior therapy guided self-help program for binge eating disorders. Findings revealed 6 themes to be considered during the cultural adaptation…

  6. A Qualitative Study of Urban Hispanic Youth in an After-School Program: Career, Cultural, and Educational Development

    Science.gov (United States)

    Perry, Justin C.; Calhoun-Butts, Candice

    2012-01-01

    Based on a diverse sample of 11 urban Hispanic youth, the career, educational, and cultural domains of developmental adjustment were investigated through a triangulation of interview data and field notes within the context of delivering an after-school program. Consensual qualitative research (CQR) and content analysis were used to explore how…

  7. Journeys in Cultural Competency: Pre-Service U.S. Teachers in Mexico Study-Abroad Programs

    Science.gov (United States)

    Santamaria, Lorri J.; Santamaria, Cristina C.; Fletcher, Todd V.

    2009-01-01

    This study investigated pre-service and credentialed teachers at 2 universities in the Southwestern United States (N = 24), who participated in education-abroad programs in Mexico over 1 summer. This study examined the literature within a framework for developing cultural competence to describe and understand students' experiences. Following a…

  8. Building Social and Cultural Capital among Young People in Disadvantaged Communities: Lessons from a Brazilian Sport-Based Intervention Program

    Science.gov (United States)

    Spaaij, Ramon

    2012-01-01

    This article explores the concepts of social and cultural capital as analytical tools for investigating the capacity of sport-based intervention programs to contribute to the personal, social and professional development of disadvantaged young people. It draws on survey data (n = 129) and qualitative interviews (n = 53) with participants of the…

  9. 22 CFR 3.12 - Exemption of grants and other foreign government assistance in cultural exchange programs from...

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Exemption of grants and other foreign government assistance in cultural exchange programs from coverage of foreign gifts and decorations legislation. 3.12 Section 3.12 Foreign Relations DEPARTMENT OF STATE GENERAL GIFTS AND DECORATIONS FROM FOREIGN GOVERNMENTS § 3.12 Exemption of grants and...

  10. Title VII Enhancement Project for Compartiendo Culturas/Sharing Cultures 1995-96. Research Report on Educational Programs.

    Science.gov (United States)

    Houston Independent School District, TX. Dept. of Research and Evaluation.

    Compartiendo Culturas/Sharing Cultures, a Title VII Two-Way Developmental Bilingual Education Program at the Gary L. Herod Elementary School in the Houston Independent School District (Texas) was designed to end the isolation typically experienced by language minority students in traditional bilingual education and to provide language majority…

  11. Effects of Explicit and Non-Explicit Versions of an Early Intervention Program Incorporating Indigenous Culture into Kindergarten Literacy Instruction

    Science.gov (United States)

    MacKay, Leslie D.; McIntosh, Kent

    2012-01-01

    Low literacy is a challenge facing Indigenous communities across North America and is an identified barrier to school success. Early literacy intervention is an important target to reduce the discrepancies in literacy outcomes. The Moe the Mouse® Speech and Language Development Program (Gardner & Chesterman, 2006) is a cultural curriculum…

  12. Promoting Social-Emotional Learning in Adolescent Latino ELLs: A Study of the Culturally Adapted "Strong Teens" Program

    Science.gov (United States)

    Castro-Olivo, Sara M.

    2014-01-01

    The current study evaluated the effects of the culturally adapted "Jóvenes Fuertes" ("Strong Teens") Social-Emotional Learning (SEL) program on the social-emotional outcomes of Latino English language learners (ELLs). A quasi-experimental design with random assignment by classrooms was used to assess the intervention's…

  13. Integrating Foreign Languages and Cultures into U.S. International Business Programs: Best Practices and Future Considerations

    Science.gov (United States)

    Sacco, Steven J.

    2014-01-01

    This paper describes the importance of foreign languages and cultures and their integration into U.S. international business programs. The author juxtaposes globalization strategies of European and American business schools and highlights pre-university foreign language study in Europe and the U.S. The paper goes on to describe model U.S.…

  14. Title VII Enhancement Project for Compartiendo Culturas/Sharing Cultures 1995-96. Research Report on Educational Programs.

    Science.gov (United States)

    Houston Independent School District, TX. Dept. of Research and Evaluation.

    Compartiendo Culturas/Sharing Cultures, a Title VII Two-Way Developmental Bilingual Education Program at the Gary L. Herod Elementary School in the Houston Independent School District (Texas) was designed to end the isolation typically experienced by language minority students in traditional bilingual education and to provide language majority…

  15. Integrating Foreign Languages and Cultures into U.S. International Business Programs: Best Practices and Future Considerations

    Science.gov (United States)

    Sacco, Steven J.

    2014-01-01

    This paper describes the importance of foreign languages and cultures and their integration into U.S. international business programs. The author juxtaposes globalization strategies of European and American business schools and highlights pre-university foreign language study in Europe and the U.S. The paper goes on to describe model U.S.…

  16. Developing Cross-Cultural Awareness through Foreign Immersion Programs: Implications of University Study Abroad Research for Global Competency Development

    Science.gov (United States)

    Lokkesmoe, Karen J.; Kuchinke, K. Peter; Ardichvili, Alexandre

    2016-01-01

    Purpose: The purpose of this paper is to investigate the efficacy of foreign immersion programs in terms of increasing cross-cultural awareness among university students in business, accounting, human resources and agriculture. The authors extrapolate from their population to the practice of developing business professionals on international…

  17. Journeys in Cultural Competency: Pre-Service U.S. Teachers in Mexico Study-Abroad Programs

    Science.gov (United States)

    Santamaria, Lorri J.; Santamaria, Cristina C.; Fletcher, Todd V.

    2009-01-01

    This study investigated pre-service and credentialed teachers at 2 universities in the Southwestern United States (N = 24), who participated in education-abroad programs in Mexico over 1 summer. This study examined the literature within a framework for developing cultural competence to describe and understand students' experiences. Following a…

  18. Indigenous Knowledge and Language: Decolonizing Culturally Relevant Pedagogy in a Mapuche Intercultural Bilingual Education Program in Chile

    Science.gov (United States)

    Ortiz, Patricio R.

    2009-01-01

    This article illustrates how Mapuche Indigenous knowledge (Kimun) and language (Mapudungun) incorporated into an Intercultural Bilingual Education (IBE) program of a school within a Mapuche context in Chile creates decolonizing counter-hegemonic narratives as forms of culturally relevant pedagogy. Based on a six-month school ethnography, this…

  19. Assessment of a new questionnaire for self-reported sun sensitivity in an occupational skin cancer screening program

    Directory of Open Access Journals (Sweden)

    Steinebrunner Beatrix

    2008-10-01

    Full Text Available Abstract Background Sun sensitivity of the skin is a risk factor for the development of cutaneous melanoma and other skin cancers. Epidemiological studies on causal factors for the development of melanoma must control for sun sensitivity as a confounder. A standardized instrument for measuring sun sensitivity has not been established yet. It is assumed that many studies show a high potential of residual confounding for sun sensitivity. In the present study, a new questionnaire for the assessment of self-reported sun sensitivity is administered and examined. Methods Prior to an occupational skin cancer screening program, the 745 participating employees were asked to fill in a questionnaire for self-assessment of sun sensitivity. The questionnaire was developed by experts of the working group "Round Table Sunbeds" (RTS to limit the health hazards of sunbed use in Germany. A sun sensitivity score (RTS-score was calculated using 10 indicators. The internal consistency of the questionnaire and the agreement with other methods (convergent validity were examined. Results The RTS-score was calculated for 655 study participants who were 18 to 65 years of age. The correlation of the items among each other was between 0.12 and 0.62. The items and the RTS-score correlated between 0.46 and 0.77. The internal consistency showed a reliability coefficient with 0.82 (Cronbach's alpha. The comparison with the Fitzpatrick classification, the prevailing standard, was possible in 617 cases with a rank correlation of rs = 0.65. The categorization of the RTS-score in four risk groups showed correct classification to the four skin types of Fitzpatrick in 75% of the cases. Other methods for the assessment of sun sensitivity displayed varying agreements with the RTS-score. Conclusion The RTS questionnaire showed a sufficient internal consistency. There is a good convergent validity between the RTS-score and the Fritzpatrick classification avoiding shortcomings of the

  20. Changing Safety Culture, One Step at a Time: The Value of the DOE-VPP Program at PNNL

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Patrick A.; Isern, Nancy G.

    2005-02-01

    The primary value of the Pacific Northwest National Laboratory (PNNL) Voluntary Protection Program (VPP) is the ongoing partnership between management and staff committed to change Laboratory safety culture one step at a time. VPP enables PNNL's safety and health program to transcend a top-down, by-the-book approach to safety, and it also raises grassroots safety consciousness by promoting a commitment to safety and health 24 hours a day, 7 days a week. PNNL VPP is a dynamic, evolving program that fosters innovative approaches to continuous improvement in safety and health performance at the Laboratory.

  1. Placing Gender in the Heart of MFT Masters Programs: Teaching a Gender Sensitive Systemic View.

    Science.gov (United States)

    Storm, Cheryl L.

    1991-01-01

    Describes masters level course for marriage and family therapists that teaches systemic underpinnings of field while also addressing feminist critique of ideas. Notes goal of course is for students to understand and adopt gender sensitive view; students then have a yardstick as they study and evaluate marriage and family therapy theories, observe…

  2. Reducing health disparities through a culturally centered mentorship program for minority faculty: the Southwest Addictions Research Group (SARG) experience.

    Science.gov (United States)

    Viets, Vanessa Lopez; Baca, Catherine; Verney, Steven P; Venner, Kamilla; Parker, Tassy; Wallerstein, Nina

    2009-08-01

    Ethnic minority faculty members are vastly underrepresented in academia. Yet, the presence of these individuals in academic institutions is crucial, particularly because their professional endeavors often target issues of health disparities. One promising way to attract and retain ethnic minority faculty is to provide them with formal mentorship. This report describes a culturally centered mentorship program, the Southwest Addictions Research Group (SARG, 2003-2007), at the University of New Mexico (UNM) that trained a cadre of minority researchers dedicated to reducing health disparities associated with substance abuse. The SARG was based at UNM's School of Medicine's Institute for Public Health, in partnership with the UNM's Center on Alcoholism, Substance Abuse, and Addictions. The program consisted of regular research meetings, collaboration with the Community Advisory Board, monthly symposia with renowned professionals, pilot projects, and conference support. The authors collected data on mentee research productivity as outcomes and conducted separate mentee and mentor focus-group interviews to assess the strengths and weaknesses of the SARG program. The SARG yielded positive outcomes as evidenced by mentee increase in grant submissions, publications, and professional presentations. Focus-group qualitative data highlighted program and institutional barriers as well as successes that surfaced during the program. Based on this evaluation, a Culturally Centered Mentorship Model (CCMM) emerged. The CCMM can help counter institutional challenges by valuing culture, community service, and community-based participatory research to support the recruitment and advancement of ethnic minority faculty members in academia.

  3. [Human bone marrow cell culture--a sensitive method for the evaluation of the biocompatibility of materials used in orthopedics].

    Science.gov (United States)

    Wilke, A; von Hirschheydt, S; Orth, J; Kienapfel, H; Griss, P; Franke, R P

    1995-01-01

    The objective of the study was to develop a test system to determine the cytotoxicity and biocompatibility of different biomaterials used in orthopedic surgery. This system was based on the use of a human bone marrow cell culture and the purpose was to find a screening method as a alternative to early animal experimental methods. The established human bone marrow cell culture has certain advantages when compared with other cell culture models. The result demonstrated a high conformity with animal experimental results.

  4. The Reciprocal Influence of Organizational Culture and Training and Development Programs: Building the Case for a Culture Analysis within Program Planning

    Science.gov (United States)

    Kissack, Heather C.; Callahan, Jamie L.

    2010-01-01

    Purpose: The purpose of this paper is to demonstrate that training designers can, and should, account for organizational culture during training needs assessments. Design/methodology/approach: Utilizing the approach and arguments in Giddens' structuration theory, the paper conceptually applies these tenets to training and development programs…

  5. The new competitive intelligence agents: "Programming" competitive intelligence ethics into corporate cultures

    Directory of Open Access Journals (Sweden)

    Betsy Van der Veer Martens

    2011-12-01

    Full Text Available This article examines some of the ethical issues involved in competitive intelligence activities on the Internet. We discuss the importance of an ethical framework for the performance of competitive intelligence, especially the Code of Ethics of SCIP (the leading professional association for strategic and competitive professionals, in the context of today's networked global environment. The virtual borderlines separating national economic and military territories online are becoming increasingly hard to determine, and a variety of intelligence activities now impact organizations of every size. We describe how competitive intelligence is often practiced by employees and firms with no clear understanding of the legal and public relations problems that various ill-advised initiatives may create for both individuals and the organization, inasmuch as the Internet greatly facilitates the use of sophisticated software products without correspondingly sophisticated ethical perspectives. Specifically, we offer two mundane and seemingly minor examples of how the uninformed use of microtasking software such as Field Agent and identity misrepresentation software such as Persona Management may actually be detrimental to the existence of an ethical organizational culture. We concludes by offering suggestions as to how to help employees "program" themselves into being effective and ethical CI "agents" for their organizations.

  6. Programmed cell death features in apple suspension cells under low oxygen culture

    Institute of Scientific and Technical Information of China (English)

    徐昌杰; 陈昆松; FERGUSONIanB

    2004-01-01

    Suspension-cultured apple fruit cells (Malus pumila Mill. cv. Braeburn) were exposed to a low oxygen atmosphere to test whether programmed cell death (PCD) has a role in cell dysfunction and death under hypoxic conditions. Protoplasts were prepared at various times after low oxygen conditions were established, and viability tested by triple staining with fluorescein diacetate (FDA), propidium iodide (PI) and Hoechst33342 (HO342). DNA breakdown and phosphatidylserine exposure on the plasma membrane were observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and annexin V binding. About 30% of protoplasts from cells after 48 h under low oxygen showed an increased accumulation of HO342, indicating increased membrane permeability. Positive TUNEL and annexin V results were also only obtained with protoplasts from cells under low oxygen. The results suggest that apple celi death under low oxygen is at least partially PCD mediated, and may explain tissue breakdown under controlled atmosphere (low oxygen) conditions in apple fruit.

  7. Programmed cell death features in apple suspension cells under low oxygen culture.

    Science.gov (United States)

    Xu, Chang-jie; Chen, Kun-song; Ferguson, Ian B

    2004-02-01

    Suspension-cultured apple fruit cells (Malus pumila Mill. cv. Braeburn) were exposed to a low oxygen atmosphere to test whether programmed cell death (PCD) has a role in cell dysfunction and death under hypoxic conditions. Protoplasts were prepared at various times after low oxygen conditions were established, and viability tested by triple staining with fluorescein diacetate (FDA), propidium iodide (PI) and Hoechst33342 (HO342). DNA breakdown and phosphatidylserine exposure on the plasma membrane were observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and annexin V binding. About 30% of protoplasts from cells after 48 h under low oxygen showed an increased accumulation of HO342, indicating increased membrane permeability. Positive TUNEL and annexin V results were also only obtained with protoplasts from cells under low oxygen. The results suggest that apple cell death under low oxygen is at least partially PCD mediated, and may explain tissue breakdown under controlled atmosphere (low oxygen) conditions in apple fruit.

  8. Programmed cell death features in apple suspension cells under low oxygen culture

    Institute of Scientific and Technical Information of China (English)

    XU Chang-jie(徐昌杰); CHEN Kun-song(陈昆松); FERGUSON Ian B.

    2004-01-01

    Suspension-cultured apple fruit cells (Malus pumila Mill. cv. Braeburn) were exposed to a low oxygen atmosphere to test whether programmed cell death (PCD) has a role in cell dysfunction and death under hypoxic conditions. Protoplasts were prepared at various times after low oxygen conditions were established, and viability tested by triple staining with fluorescein diacetate (FDA), propidium iodide (PI) and Hoechst33342 (HO342). DNA breakdown and phosphatidylserine exposure on the plasma membrane were observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and annexin V binding. About 30% of protoplasts from cells after 48 h under low oxygen showed an increased accumulation of HO342, indicating increased membrane permeability. Positive TUNEL and annexin V results were also only obtained with protoplasts from cells under low oxygen. The results suggest that apple cell death under low oxygen is at least partially PCD mediated, and may explain tissue breakdown under controlled atmosphere (low oxygen) conditions in apple fruit.

  9. DoD Information Security Program and Protection of Sensitive Compartmented Information (SCI)

    Science.gov (United States)

    2016-04-21

    Sensitive Compartmented Information (SCI) References: See Enclosure 1 1. PURPOSE . In accordance with the authority in DoD Directive (DoDD...Inspector General of the Department of Defense are forwarded to the office of the Inspector General for processing. (2) A database to facilitate...Defense for Intelligence PART II. DEFINITIONS Unless otherwise noted, the following terms and their definitions are for the purposes of this

  10. Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening

    Energy Technology Data Exchange (ETDEWEB)

    Jiguet Jiglaire, Carine, E-mail: carine.jiguet-jiglaire@univ-amu.fr [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); Baeza-Kallee, Nathalie; Denicolaï, Emilie; Barets, Doriane [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); Metellus, Philippe [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); APHM, Timone Hospital, Department of Neurosurgery, 13005 Marseille (France); Timone Hospital, 264 Rue Saint Pierre, 13385 Marseille Cedex 5 (France); and others

    2014-02-15

    Identification of new drugs and predicting drug response are major challenges in oncology, especially for brain tumors, because total surgical resection is difficult and radiation therapy or chemotherapy is often ineffective. With the aim of developing a culture system close to in vivo conditions for testing new drugs, we characterized an ex vivo three-dimensional culture system based on a hyaluronic acid-rich hydrogel and compared it with classical two-dimensional culture conditions. U87-MG glioblastoma cells and seven primary cell cultures of human glioblastomas were subjected to radiation therapy and chemotherapy drugs. It appears that 3D hydrogel preserves the original cancer growth behavior and enables assessment of the sensitivity of malignant gliomas to radiation and drugs with regard to inter-tumoral heterogeneity of therapeutic response. It could be used for preclinical assessment of new therapies. - Highlights: • We have compared primary glioblastoma cell culture in a 2D versus 3D-matrix system. • In 3D morphology, organization and markers better recapitulate the original tumor. • 3D-matrix culture might represent a relevant system for more accurate drug screening.

  11. Increasing Self-Awareness, Decreasing Dogmatism and Expanding Disciplinary Horizons: Synthesising a Plan of Action towards Culture-Sensitivity

    Science.gov (United States)

    Persson, Roland S.

    2012-01-01

    The author recognises the fact that knowledge of cultural diversity and its implications is growing in the field of giftedness research and practice. In some ways, the target article could therefore be considered "old news." The author contends that his effort to address culture variation and its problematic impact on research, however, is not to…

  12. Are Perfectionism, Individualism, and Racial Color-Blindness Associated with Less Cultural Sensitivity? Exploring Diversity Awareness in White Prospective Teachers

    Science.gov (United States)

    Wang, Kenneth T.; Castro, Antonio J.; Cunningham, Yu Li

    2014-01-01

    Cultural ideologies of meritocracy and individualism act as strong barriers for college students in understanding the most complex systems of inequity across racial, cultural, and gendered lines. The dichotomous thinking patterns of maladaptive perfectionists may also relate to resistance of multicultural awareness. This study examined whether…

  13. Are Perfectionism, Individualism, and Racial Color-Blindness Associated with Less Cultural Sensitivity? Exploring Diversity Awareness in White Prospective Teachers

    Science.gov (United States)

    Wang, Kenneth T.; Castro, Antonio J.; Cunningham, Yu Li

    2014-01-01

    Cultural ideologies of meritocracy and individualism act as strong barriers for college students in understanding the most complex systems of inequity across racial, cultural, and gendered lines. The dichotomous thinking patterns of maladaptive perfectionists may also relate to resistance of multicultural awareness. This study examined whether…

  14. Robust Coordination of Autonomous Systems through Risk-sensitive, Model-based Programming and Execution

    Science.gov (United States)

    2015-10-09

    describe cRMPL, an extension of the model-based program- ming language RMPL [6] that allows missions with state and temporal uncer- tainty, in...14 3.3.1 Temporal constraints . . . . . . . . . . . . . . . . . . . . 15 3.3.2 State constraints...Simple UAV scenario in cRMPL . . . . . . . . . . . . . . . . . . 19 4 Risk-bounded consistency of Probabilistic Temporal Plan Networks 21 4.1

  15. Sensitivity analysis of efficient solution in vector MINMAX boolean programming problem

    Directory of Open Access Journals (Sweden)

    Vladimir A. Emelichev

    2002-07-01

    Full Text Available We consider a multiple criterion Boolean programming problem with MINMAX partial criteria. The extreme level of independent perturbations of partial criteria parameters such that efficient (Pareto optimal solution preserves optimality was obtained. MSC: 90C29, 90C31

  16. A culturally specific health coaching program targeting cardiovascular disease risk in South Asians: rationale, design, and baseline data.

    Science.gov (United States)

    Sathe, Anita; Flowers, Elena; Mathur, Avantika; Garcia, Donna Malhotra; Kotrys, Jeannette; Gandhi, Rupal; Molina, César; Mathur, Ashish

    2013-01-01

    Health coaching is an effective strategy for improving cardiovascular disease risk factors. Coaching interventions have primarily been studied in Caucasians, and the effectiveness in other ethnic groups is not known. Further, adaptation of coaching to include culturally specific components has not been studied. Our aim is to describe a culturally specific coaching program targeted at reducing cardiovascular disease risk in South Asians. Participants initially underwent comprehensive cardiovascular disease risk screening, then received individualized risk assessment and behavioral recommendations. A health coach then contacted participants regularly for one year to provide encouragement with behavior change, troubleshoot challenges, and assess adherence. In the first five years of the program, 3,180 people underwent risk assessment, 3,132 were candidates for coaching, 2,726 indicated a desire to participate in coaching, 1,359 received coaching, and 1,051 completed coaching for at least one year. Culturally specific health coaching is an appealing and feasible intervention for reducing cardiovascular disease risk in South Asians, with very low attrition. Coaching strategies for risk reduction are proven to be effective, but further longitudinal research is needed to determine whether the impact of incorporating cultural specificity improves the effectiveness. This program utilizes non-medically trained personnel as coaches and is relatively inexpensive, with potential for great cost savings in prevention of cardiovascular disease.

  17. Therapist turnover and new program sustainability in mental health clinics as a function of organizational culture, climate, and service structure.

    Science.gov (United States)

    Glisson, Charles; Schoenwald, Sonja K; Kelleher, Kelly; Landsverk, John; Hoagwood, Kimberly Eaton; Mayberg, Stephen; Green, Philip

    2008-03-01

    The present study incorporates organizational theory and organizational characteristics in examining issues related to the successful implementation of mental health services. Following the theoretical foundations of socio-technical and cultural models of organizational effectiveness, organizational climate, culture, legal and service structures, and workforce characteristics are examined as correlates of therapist turnover and new program sustainability in a nationwide sample of mental health clinics. Results of General Linear Modeling (GLM) with the organization as the unit of analysis revealed that organizations with the best climates as measured by the Organizational Social Context (OSC) profiling system, had annual turnover rates (10%) that were less than half the rates found in organizations with the worst climates (22%). In addition, organizations with the best culture profiles sustained new treatment or service programs over twice as long (50 vs. 24 months) as organizations with the worst cultures. Finally, clinics with separate children's services units had higher turnover rates than clinics that served adults and children within the same unit. The findings suggest that strategies to support the implementation of new mental health treatments and services should attend to organizational culture and climate, and to the compatibility of organizational service structures with the demand characteristics of treatments.

  18. A Comprehensive Mathematical Programming Model for Minimizing Costs in A Multiple-Item Reverse Supply Chain with Sensitivity Analysis

    Directory of Open Access Journals (Sweden)

    Mahmoudi Hoda

    2014-09-01

    Full Text Available These instructions give you guidelines for preparing papers for IFAC conferences. A reverse supply chain is configured by a sequence of elements forming a continuous process to treat return-products until they are properly recovered or disposed. The activities in a reverse supply chain include collection, cleaning, disassembly, test and sorting, storage, transport, and recovery operations. This paper presents a mathematical programming model with the objective of minimizing the total costs of reverse supply chain including transportation, fixed opening, operation, maintenance and remanufacturing costs of centers. The proposed model considers the design of a multi-layer, multi-product reverse supply chain that consists of returning, disassembly, processing, recycling, remanufacturing, materials and distribution centers. This integer linear programming model is solved by using Lingo 9 software and the results are reported. Finally, a sensitivity analysis of the proposed model is also presented.

  19. HOW SENSITIVE ARE CROP YIELDS TO PRICE CHANGES AND FARM PROGRAMS?

    OpenAIRE

    Choi, Jung-Sup; Helmberger, Peter G.

    1993-01-01

    A two-stage approach is used to estimate sensitivity of corn, wheat, and soybean yields to changes in prices and land idled. Estimated elasticity of demand for fertilizer per acre with respect to expected output price equals 0.47, 0.10, and 0.82 for corn, wheat, and soybeans. Upper estimates of the elasticity of yield with respect to fertilizer equals +0.58, +0.29, and +0.16 for corn, wheat, and soybeans. Yields are found to be quite insensitive to price changes. Fertilizer demands and yields...

  20. Down-modulation of antigen-induced activation of murine cultured mast cells sensitized with a highly cytokinergic IgE clone.

    Science.gov (United States)

    Sakanaka, Mariko; Kurimune, Yuki; Yamada, Keiko; Hyodo, Nao; Natsuhara, Mayuko; Ichikawa, Atsushi; Furuta, Kazuyuki; Tanaka, Satoshi

    2016-06-01

    Accumulating evidence suggests that several IgE clones can activate mast cells during the sensitization phase even in the absence of antigen. They were found to induce pro-inflammatory cytokine release, histamine synthesis, chemotaxis, adhesion, and accelerated maturation of mast cells, although it remains unknown whether antigen-induced responses can be affected by differences of IgE clones. We compared two IgE clones, which were different in the capacity to activate mast cells during sensitization, in terms of potentials to affect antigen-induced degranulation and cytokine releases using IL-3-dependent murine bone marrow-derived cultured mast cells (BMMCs). Antigen-induced degranulation and pro-inflammatory cytokine release were augmented, when BMMCs were sensitized with elevated concentrations of a clone IgE-3, which did not induce phosphorylation of JNK and cytokine release in the absence of antigen, whereas those were significantly rather decreased, when BMMCs were sensitized with elevated concentrations of a clone SPE-7, one of the most potent cytokinergic IgE clones, which intensively induced phosphorylation of JNK. This attenuated response with SPE-7 was accompanied by decreased tyrosine phosphorylation of the cellular proteins including Syk upon antigen stimulation. SP600125, which is known to inhibit JNK, restored the levels of antigen-induced degranulation and phosphorylation of Syk in BMMCs sensitized with higher concentrations of a clone SPE-7 when it was added before sensitization. Treatment with anisomycin, a potent activator of JNK, before IgE sensitization significantly suppressed antigen-induced degranulation. These findings suggest that differences of sensitizing IgE clones can affect antigen-induced responses and activation of JNK during sensitization might suppress antigen-induced activation of mast cells.

  1. Toward a common nuclear safety culture. From knowledge creation to competence building in Euratom programs

    Energy Technology Data Exchange (ETDEWEB)

    Goethem, Georges van [EC DG Research J2 / Euratom (Fission), Brussels (Belgium). Innovation in Nuclear Systems, and Education and Training

    2010-11-15

    One of the main goals of the Euratom research and training programs is to contribute to the sustainability of nuclear energy by providing resources, in particular, for research and innovation in Generations II, IIII and IV (knowledge creation). Euratom training programs contribute most notably to competence building while facilitating the mutual recognition of experts and thereby continuously improving the nuclear safety culture. The Sustainable Nuclear Energy Technology Platform (SNE-TP), composed of all stakeholders of nuclear fission and radiation protection (over 75 organizations), is a driving force therein. The emphasis in this paper is on nuclear competence building under the current 7-th Euratom Framework Programme (2007 - 2013). The employers (in particular, the nuclear industry and the technical safety organisations) are naturally involved in this process. According to the IAEA definition, competence means the ability to apply knowledge, skills and attitudes so as to perform a job in an effective and efficient manner and to an established standard (S.S.S. No. RS-G-1.4 / 2001). Knowledge is usually created in higher education institutions (e.g., universities) and in (private and public) research organizations. Skills and attitudes are usually the result of specific training and on-the-job experience throughout professional life. Euratom training activities are traditionally addressed to scientists and experts with higher education. Special attention is devoted to the continuous improvement of their competencies through borderless mobility and lifelong learning in synergy with the main stakeholders. The Euratom training strategy is based on 3 objectives: 1. Analysis of the needs of society and industry with regard to a common nuclear safety culture. This issue raises important questions, for examples: What should be added to existing training schemes? How could Continuous Professional Development (CPD) be improved? Is mobility and mutual recognition of

  2. Programmed cell death activated by Rose Bengal in Arabidopsis thaliana cell suspension cultures requires functional chloroplasts.

    Science.gov (United States)

    Gutiérrez, Jorge; González-Pérez, Sergio; García-García, Francisco; Daly, Cara T; Lorenzo, Oscar; Revuelta, José L; McCabe, Paul F; Arellano, Juan B

    2014-07-01

    Light-grown Arabidopsis thaliana cell suspension culture (ACSC) were subjected to mild photooxidative damage with Rose Bengal (RB) with the aim of gaining a better understanding of singlet oxygen-mediated defence responses in plants. Additionally, ACSC were treated with H2O2 at concentrations that induced comparable levels of protein oxidation damage. Under low to medium light conditions, both RB and H2O2 treatments activated transcriptional defence responses and inhibited photosynthetic activity, but they differed in that programmed cell death (PCD) was only observed in cells treated with RB. When dark-grown ACSC were subjected to RB in the light, PCD was suppressed, indicating that the singlet oxygen-mediated signalling pathway in ACSC requires functional chloroplasts. Analysis of up-regulated transcripts in light-grown ACSC, treated with RB in the light, showed that both singlet oxygen-responsive transcripts and transcripts with a key role in hormone-activated PCD (i.e. ethylene and jasmonic acid) were present. A co-regulation analysis proved that ACSC treated with RB exhibited higher correlation with the conditional fluorescence (flu) mutant than with other singlet oxygen-producing mutants or wild-type plants subjected to high light. However, there was no evidence for the up-regulation of EDS1, suggesting that activation of PCD was not associated with the EXECUTER- and EDS1-dependent signalling pathway described in the flu mutant. Indigo Carmine and Methylene Violet, two photosensitizers unable to enter chloroplasts, did not activate transcriptional defence responses in ACSC; however, whether this was due to their location or to their inherently low singlet oxygen quantum efficiencies was not determined.

  3. The Sensitivity, Specificity and Predictive Values of Snellen Chart Compared to the Diagnostic Test in Amblyopia Screening Program in Iran

    Directory of Open Access Journals (Sweden)

    Fatemeh Rivakani

    2015-12-01

    Full Text Available Introduction Amblyopia is a leading cause of visual impairment in both childhood and adult populations. Our aim in this study was to assess the epidemiological characteristics of the amblyopia screening program in Iran. Materials and Methods A cross-sectional study was done on a randomly selected sample of 4,636 Iranian children who were referred to screening program in 2013 were participated in validity study, too. From each provinces the major city were selected. Screening and diagnostic tests were done by instructors in first stage and optometrists in second stage, respectively. Finally data were analyzed by Stata version 13. Results The sensitivity was ranged from 74% to 100% among the various provinces such that Fars and Ardabil province had maximum and minimum values, respectively. The pattern of specificity was differ and ranged 44% to 84% among the provinces; Hormozgan and Fars had maximum and minimum values, respectively. The positive predictive value was also ranged from 35% to %81 which was assigned to Khuzestan and Ardabil provinces, respectively. The range of Negative Predictive value was 61% to 100% which was belonged to Ardabil and Fars provinces. Conclusion The total sensitivity (89% and negative predictive values (93% of screening test among children aged 3-6 years is acceptable, but only 51% of children refereed to second stage are true positive and this imposes considerable cost to health system.

  4. A simple colony-formation assay in liquid medium, termed 'tadpoling', provides a sensitive measure of Saccharomyces cerevisiae culture viability.

    Science.gov (United States)

    Welch, Aaron Z; Koshland, Douglas E

    2013-12-01

    Here we describe the first high-throughput amenable method of quantifying Saccharomyces cerevisiae culture viability. Current high-throughput methods of assessing yeast cell viability, such as flow cytometry and SGA analysis, do not measure the percentage viability of a culture but instead measure cell vitality or colony fitness, respectively. We developed a method, called tadpoling, to quantify the percentage viability of a yeast culture, with the ability to detect as few as one viable cell amongst ~10(8) dead cells. The most important feature of this assay is the exploitation of yeast colony formation in liquid medium. Utilizing a microtiter dish, we are able to observe a range of viability of 100% to 0.0001%. Comparison of tadpoling to the traditional plating method to measure yeast culture viability reveals that, for the majority of Saccharomyces species analyzed there is no significant difference between the two methods. In comparison to flow cytometry using propidium iodide, the high-throughput method of measuring yeast culture viability, tadpoling is much more accurate at culture viabilities viability.

  5. TV programs that denounce unfair advantage impact women's sensitivity to defection in the public goods game.

    Science.gov (United States)

    Park, Seongmin A; Jeong, Soyeong; Jeong, Jaeseung

    2013-01-01

    We explore the neural underpinnings of gender differences in cooperation and their modulation by intensive media watching. We compared cooperative decisions and electroencephalograph data between genders from who participated in repeated rounds of the public goods game (PGG) and investigated within groups changes that occurred after watching a TV program known as "investigative reporting" that denounces unfair advantages taken by free-riders against the public. Women tended to be more cooperative than men during early rounds of PGG, mostly because they react differently to the defection of others; women also had greater β and γ band activity in regions estimated to be associated with social cognition. These gender differences disappeared after participants watched the TV programs: women were more likely to choose free-riding in response to the defection of others that elicits significant increases in γ band activities that were estimated to be right insula. Greater activity in social cognition leads women to make decisions considering the motives of others, while men tend to make a decision by complying with the social norm. Watching the investigative TV reports produced a greater negative emotion to the defection and led women, in a similar manner as men, to opt for a "tit-for-tat" strategy.

  6. An Investigation of a Culturally Responsive Approach to Science Education in a Summer Program for Marginalized Youth

    Science.gov (United States)

    Garvin, Brittany A.

    There have been numerous calls and efforts made to provide states, school districts, and communities needed financial support to increase and enhance access to and opportunities in Science, Technology, Engineering, and Math (STEM) related disciplines for marginalized populations (Tyson, Lee, & Hanson, 2007; Caldwell & Siwatu, 2003). As the challenge to better educate students of color and poor students intensifies, the need to provide equitable science learning experiences for all students aimed at scientific literacy and STEM also becomes critical. Thus the need to provide summer science enrichment programs where students engage in scientific experimentation, investigation, and critical thinking are vital to helping students who have been traditionally marginalized achieve success in school science and enter the science career pipeline. This mixed methods study examined the impact of a culturally responsive approach on student attitudes, interests in science education and STEM careers, and basic science content knowledge before and after participation in an upward bound summer program. Quantitative results indicated using a culturally responsive approach to teach science in an informal learning space significantly increases student achievement. Students receiving culturally responsive science instruction exhibited statistically significant increases in their posttest science scores compared to pretest science scores, M = 0.376, 95% CI [0.266, 0.487], t (10) = 7.610, p learn science utilizing a culturally responsive approach was much more beneficial to their overall science knowledge, as it allowed students to experience, understand, and connect to and through their science learning. Likewise, culturally responsive science instruction helped students to foster a more positive interest in science and STEM careers as it provided students the opportunity to do science in a meaningful and relevant way. Moreover, results revealed students receiving culturally responsive

  7. Comparison of the sensitivity of culture, PCR and quantitative real-time PCR for the detection of Pseudomonas aeruginosa in sputum of cystic fibrosis patients

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    De Vos Daniel

    2009-11-01

    Full Text Available Abstract Background Pseudomonas aeruginosa is the major pathogen involved in the decline of lung function in cystic fibrosis (CF patients. Early aggressive antibiotic therapy has been shown to be effective in preventing chronic colonization. Therefore, early detection is important and sensitive detection methods are warranted. In this study, we used a dilution series of P. aeruginosa positive sputa, diluted in a pool of P. aeruginosa negative sputa, all from CF patients - to mimick as closely as possible the sputa sent to routine laboratories - to compare the sensitivity of three culture techniques versus that of two conventional PCR formats and four real-time PCR formats, each targeting the P. aeruginosa oprL gene. In addition, we compared five DNA-extraction protocols. Results In our hands, all three culture methods and the bioMérieux easyMAG Nuclisens protocol Generic 2.0.1, preceded by proteinase K pretreatment and followed by any of the 3 real-time PCR formats with probes were most sensitive and able to detect P. aeruginosa up to 50 cfu/ml, i.e. the theoretical minimum of one cell per PCR mixture, when taking into account the volumes used in this study of sample for DNA-extraction, of DNA-elution and of DNA-extract in the PCR mixture. Conclusion In this study, no difference in sensitivity could be found for the detection of P. aeruginosa from sputum between microbiological culture and optimized DNA-extraction and real-time PCR. The results also indicate the importance of the optimization of the DNA-extraction protocol and the PCR format.

  8. Economic value analysis of the return from the Korean astronaut program and the science culture diffusion activity in Korea

    Science.gov (United States)

    Yi, Soyeon; Jang, Hyun-Jin; Lee, Hyo Suk; Yu, Jong-Phil; Kim, Soyeon; Lee, Joohee; Hur, Hee-Young

    2013-06-01

    In this study, we analyze the economic effects from the Korean Astronaut Program (KAP) and the subsequent Science Culture Diffusion Activity (SCDA). Korea has had a huge practical effect on the development of science and technology and has increased international awareness of Korea by producing Korea's first astronaut. There has also been a large, ripple effect on space related industries. In addition, the KAP has exercised a far-reaching influence on Korean society and culture by boosting all science and engineering and inspiring national pride. After the KAP, astronauts' outreach activities, such as lectures for the general public; interviews on television, newspapers and magazines; participating in children's science camps; and distributing publications and DVDs about astronaut program for general public, were instituted for diffusing science culture. Thus, positive effects such as the promotion of Korea's level of technology, student interest in science and engineering fields, and the expansion of the industrial base were reinforced after the KAP. This study is aimed at evaluating the economic significance and the value of return through analyzing the effects of the KAP and the subsequent Science Culture Diffusion Activity.

  9. Mexican American women's perspectives on a culturally adapted cognitive-behavioral therapy guided self-help program for binge eating.

    Science.gov (United States)

    Shea, Munyi; Cachelin, Fary M; Gutierrez, Guadalupe; Wang, Sherry; Phimphasone, Phoutdavone

    2016-02-01

    The prevalence of bulimia nervosa (BN) and binge eating disorder (BED) among Latinas is comparable to those of the general population; however, few interventions and treatment trial research have focused on this group. Cognitive-behavioral therapy (CBT) is the treatment of choice for binge eating related disorders. CBT-based guided self-help (CBTgsh)-a low-cost minimal intervention-has also been shown effective in improving binge eating related symptom, but the effectiveness of the CBTgsh among ethnic minority women is not well understood. Cultural adaptation of evidence-based treatments can be an important step for promoting treatment accessibility and engagement among underserved groups. This qualitative study was part of a larger investigation that examined the feasibility and efficacy of a culturally adapted CBTgsh program among Mexican American women with binge eating disorders. Posttreatment focus groups were conducted with 12 Mexican American women with BN or BED who participated in the intervention. Data were analyzed with the grounded theory methodology (Corbin & Strauss, 2008). Three themes emerged from the data: (a) eating behavior and body ideals are socially and culturally constructed, (b) multifaceted support system is crucial to Mexican American women's treatment engagement and success, and (c) the culturally adapted CBTgsh program is feasible and relevant to Mexican American women's experience, but it can be strengthened with increased family and peer involvement. The findings provide suggestions for further adaptation and refinement of the CBTgsh, and implications for future research as well as early intervention for disordered eating in organized care settings.

  10. Why Culture Matters: An Empirically-Based Pre-Deployment Training Program

    Science.gov (United States)

    2005-09-01

    Almond and Verba 1963). 8 At the meso-level, typically theories are concerned with describing culture as common norms, practices, or patterns of...Decision: Explaining the Cuban Missile Crisis, 2nd Ed. Reading, MA: Longman. Almond and Verba . 1963. The Civic Culture: Political Attitudes and

  11. Toward Defining Programs and Services for Culturally and Linguistically Diverse Learners in Special Education.

    Science.gov (United States)

    Garcia, Shernaz B.; Malkin, Diana H.

    1993-01-01

    Intended to help special educators with culturally and linguistically diverse learners, this article discusses the importance of addressing students' language characteristics, developing a language use plan, recognizing the important influence of cultural factors on childrearing practices and communication styles, selecting appropriate…

  12. Evaluating Socio-Cultural Pedagogy in a Distance Teacher Education Program

    Science.gov (United States)

    Teemant, Annela

    2005-01-01

    Increasing pressure has been placed on teacher education to prepare teachers to educate bilingual/bicultural students using scientifically-based teaching methods. Socio-cultural theory and pedagogy have emerged as a research-based foundation for diversity teacher preparation. Socio-cultural theory rests on the premise that learning is social,…

  13. Diagnostic Algorithm Using a Sensitive Broth Culture Method for Detection of Clostridium difficile Toxin from Stool Samples

    Directory of Open Access Journals (Sweden)

    Paul Bayardelle

    2009-01-01

    Full Text Available BACKGROUND: The two-step glutamate dehydrogenase antigencytotoxicity neutralization assay algorithm has been found to be reliable for the diagnosis of toxigenic Clostridium difficile. However, the high sensitivity of the screening method is compromised by the relative low sensitivity of the second step, the direct cytotoxin neutralization assay (DCNA using a fecal filtrate. The objective of the present study was to compare the DCNA with an indirect cytotoxin neutralization assay (ICNA.

  14. Fetal stress and programming of hypoxic/ischemic-sensitive phenotype in the neonatal brain: mechanisms and possible interventions.

    Science.gov (United States)

    Li, Yong; Gonzalez, Pablo; Zhang, Lubo

    2012-08-01

    Growing evidence of epidemiological, clinical and experimental studies has clearly shown a close link between adverse in utero environment and the increased risk of neurological, psychological and psychiatric disorders in later life. Fetal stresses, such as hypoxia, malnutrition, and fetal exposure to nicotine, alcohol, cocaine and glucocorticoids may directly or indirectly act at cellular and molecular levels to alter the brain development and result in programming of heightened brain vulnerability to hypoxic-ischemic encephalopathy and the development of neurological diseases in the postnatal life. The underlying mechanisms are not well understood. However, glucocorticoids may play a crucial role in epigenetic programming of neurological disorders of fetal origins. This review summarizes the recent studies about the effects of fetal stress on the abnormal brain development, focusing on the cellular, molecular and epigenetic mechanisms and highlighting the central effects of glucocorticoids on programming of hypoxic-ischemic-sensitive phenotype in the neonatal brain, which may enhance the understanding of brain pathophysiology resulting from fetal stress and help explore potential targets of timely diagnosis, prevention and intervention in neonatal hypoxic-ischemic encephalopathy and other brain disorders.

  15. Fetal Stress and Programming of Hypoxic/Ischemic-Sensitive Phenotype in the Neonatal Brain: Mechanisms and Possible Interventions

    Science.gov (United States)

    Li, Yong; Gonzalez, Pablo; Zhang, Lubo

    2012-01-01

    Growing evidence of epidemiological, clinical and experimental studies has clearly shown a close link between adverse in utero environment and the increased risk of neurological, psychological and psychiatric disorders in later life. Fetal stresses, such as hypoxia, malnutrition, and fetal exposure to nicotine, alcohol, cocaine and glucocorticoids may directly or indirectly act at cellular and molecular levels to alter the brain development and result in programming of heightened brain vulnerability to hypoxic-ischemic encephalopathy and the development of neurological diseases in the postnatal life. The underlying mechanisms are not well understood. However, glucocorticoids may play a crucial role in epigenetic programming of neurological disorders of fetal origins. This review summarizes the recent studies about the effects of fetal stress on the abnormal brain development, focusing on the cellular, molecular and epigenetic mechanisms and highlighting the central effects of glucocorticoids on programming of hypoxicischemic-sensitive phenotype in the neonatal brain, which may enhance the understanding of brain pathophysiology resulting from fetal stress and help explore potential targets of timely diagnosis, prevention and intervention in neonatal hypoxic-ischemic encephalopathy and other for brain disorders. PMID:22627492

  16. Barriers to accessing the culturally sensitive healthcare that could decrease the disabling effects of arthritis in a rural Mayan community: a qualitative inquiry.

    Science.gov (United States)

    Loyola-Sanchez, Adalberto; Richardson, Julie; Wilkins, Seanne; Lavis, John N; Wilson, Michael G; Alvarez-Nemegyei, Jose; Pelaez-Ballestas, Ingris

    2016-05-01

    The impact of living with arthritis in a rural Mexican Mayan community along with the barriers encountered by people living with this chronic condition were investigated in this study. The community needs around this health issue were investigated by conducting an ethnographic study using data obtained during two time periods (August 2012-April 2013 and December 2013-December 2014). During the first period, fieldwork observations and interviews with 65 individuals, which included people with arthritis, health professionals, traditional health providers, and community leaders were undertaken. During the second period, 46 community meetings were conducted to identify the needs associated with arthritis in the municipality. Data were analyzed following a modified version of the Framework approach. The results show that arthritis reduces the health-related quality of life of the people in Chankom through a process of disablement, conditioning a need to access culturally sensitive healthcare. Availability, attainability, and acceptability barriers prevent access to this type of healthcare and result from power imbalance between indigenous and non-indigenous people. There is a need to develop culturally sensitive rehabilitation services for people living with arthritis in Chankom. Mayan people should be involved in the design and implementation of these services. Moreover, it is important to improve our understanding of the processes behind the healthcare access inequities identified in this study by attending to the historical generation of current social, economical, cultural, and political structures.

  17. Results of a psychosomatic training program in China, Vietnam and Laos: successful cross-cultural transfer of a postgraduate training program for medical doctors

    Directory of Open Access Journals (Sweden)

    Fritzsche Kurt

    2012-08-01

    Full Text Available Abstract Background With the “ASIA-LINK” program, the European Community has supported the development and implementation of a curriculum of postgraduate psychosomatic training for medical doctors in China, Vietnam and Laos. Currently, these three countries are undergoing great social, economic and cultural changes. The associated psychosocial stress has led to increases in psychological and psychosomatic problems, as well as disorders for which no adequate medical or psychological care is available, even in cities. Health care in these three countries is characterized by the coexistence of Western medicine and traditional medicine. Psychological and psychosomatic disorders and problems are insufficiently recognized and treated, and there is a need for biopsychosocially orientated medical care. Little is known about the transferability of Western-oriented psychosomatic training programs in the Southeast Asian cultural context. Methods The curriculum was developed and implemented in three steps: 1 an experimental phase to build a future teacher group; 2 a joint training program for future teachers and German teachers; and 3 training by Asian trainers that was supervised by German teachers. The didactic elements included live patient interviews, lectures, communication skills training and Balint groups. The training was evaluated using questionnaires for the participants and interviews of the German teachers and the future teachers. Results Regional training centers were formed in China (Shanghai, Vietnam (Ho Chi Minh City and Hue and Laos (Vientiane. A total of 200 physicians completed the training, and 30 physicians acquired the status of future teacher. The acceptance of the training was high, and feelings of competence increased during the courses. The interactive training methods were greatly appreciated, with the skills training and self-experience ranked as the most important topics. Adaptations to the cultural background of the

  18. The Development and Application of a STEAM Program Based on Traditional Korean Culture

    Science.gov (United States)

    Kim, Hyoungbum; Chae, Dong-Hyun

    2016-01-01

    The purpose of this research was to develop a STEAM program in the context of teaching and learning a traditional Korean instrument and implement it in a high school class to determine the program's effectiveness. The STEAM program was developed through a continuous consultation process between a development team and external experts, including an…

  19. The Development and Application of a STEAM Program Based on Traditional Korean Culture

    Science.gov (United States)

    Kim, Hyoungbum; Chae, Dong-Hyun

    2016-01-01

    The purpose of this research was to develop a STEAM program in the context of teaching and learning a traditional Korean instrument and implement it in a high school class to determine the program's effectiveness. The STEAM program was developed through a continuous consultation process between a development team and external experts, including an…

  20. Grader agreement, and sensitivity and specificity of digital photography in a community optometry-based diabetic eye screening program

    Directory of Open Access Journals (Sweden)

    Sellahewa L

    2014-07-01

    Full Text Available Luckni Sellahewa,1,2 Craig Simpson,2 Prema Maharajan,2 John Duffy,2 Iskandar Idris3 1Diabetic Medicine Department, Nottingham University Hospitals, 2North Nottinghamshire Eye Screening Service, Sherwood Forest Hospitals Foundation Trust, 3Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Nottingham, UK Background: Digital retinal photography with mydriasis is the preferred modality for diabetes eye screening. The purpose of this study was to evaluate agreement in grading levels between primary and secondary graders and to calculate their sensitivity and specificity for identifying sight-threatening disease in an optometry-based retinopathy screening program.Methods: This was a retrospective study using data from 8,977 patients registered in the North Nottinghamshire retinal screening program. In all cases, the ophthalmology diagnosis was used as the arbitrator and considered to be the gold standard. Kappa statistics were used to evaluate the level of agreement between graders.Results: Agreement between primary and secondary graders was 51.4% and 79.7% for detecting no retinopathy (R0 and background retinopathy (R1, respectively. For preproliferative (R2 and proliferative retinopathy (R3 at primary grading, agreement between the primary and secondary grader was 100%. Where there was disagreement between the primary and secondary grader for R1, only 2.6% (n=41 were upgraded by an ophthalmologist. The sensitivity and specificity for detecting R3 was 78.2% and 98.1%, respectively. None of the patients upgraded from any level of retinopathy to R3 required photocoagulation therapy. The observed kappa between the primary and secondary grader was 0.3223 (95% confidence interval 0.2937–0.3509, ie, fair agreement, and between the primary grader and ophthalmology for R3 was 0.5667 (95% confidence interval 0.4557–0.6123, ie, moderate agreement. Conclusion: These data provide information on the

  1. Development of a Highly Sensitive Cell-Based Assay for Detecting Botulinum Neurotoxin Type A through Neural Culture Media Optimization.

    Science.gov (United States)

    Hong, Won S; Pezzi, Hannah M; Schuster, Andrea R; Berry, Scott M; Sung, Kyung E; Beebe, David J

    2016-01-01

    Botulinum neurotoxin (BoNT) is the most lethal naturally produced neurotoxin. Due to the extreme toxicity, BoNTs are implicated in bioterrorism, while the specific mechanism of action and long-lasting effect was found to be medically applicable in treating various neurological disorders. Therefore, for both public and patient safety, a highly sensitive, physiologic, and specific assay is needed. In this paper, we show a method for achieving a highly sensitive cell-based assay for BoNT/A detection using the motor neuron-like continuous cell line NG108-15. To achieve high sensitivity, we performed a media optimization study evaluating three commercially available neural supplements in combination with retinoic acid, purmorphamine, transforming growth factor β1 (TGFβ1), and ganglioside GT1b. We found nonlinear combinatorial effects on BoNT/A detection sensitivity, achieving an EC50 of 7.4 U ± 1.5 SD (or ~7.9 pM). The achieved detection sensitivity is comparable to that of assays that used primary and stem cell-derived neurons as well as the mouse lethality assay.

  2. A voltage-sensitive dye-based assay for the identification of differentiated neurons derived from embryonic neural stem cell cultures.

    Directory of Open Access Journals (Sweden)

    Richardson N Leão

    Full Text Available BACKGROUND: Pluripotent and multipotent stem cells hold great therapeutical promise for the replacement of degenerated tissue in neurological diseases. To fulfill that promise we have to understand the mechanisms underlying the differentiation of multipotent cells into specific types of neurons. Embryonic stem cell (ESC and embryonic neural stem cell (NSC cultures provide a valuable tool to study the processes of neural differentiation, which can be assessed using immunohistochemistry, gene expression, Ca(2+-imaging or electrophysiology. However, indirect methods such as protein and gene analysis cannot provide direct evidence of neuronal functionality. In contrast, direct methods such as electrophysiological techniques are well suited to produce direct evidence of neural functionality but are limited to the study of a few cells on a culture plate. METHODOLOGY/PRINCIPAL FINDINGS: In this study we describe a novel method for the detection of action potential-capable neurons differentiated from embryonic NSC cultures using fast voltage-sensitive dyes (VSD. We found that the use of extracellularly applied VSD resulted in a more detailed labeling of cellular processes compared to calcium indicators. In addition, VSD changes in fluorescence translated precisely to action potential kinetics as assessed by the injection of simulated slow and fast sodium currents using the dynamic clamp technique. We further demonstrate the use of a finite element model of the NSC culture cover slip for optimizing electrical stimulation parameters. CONCLUSIONS/SIGNIFICANCE: Our method allows for a repeatable fast and accurate stimulation of neurons derived from stem cell cultures to assess their differentiation state, which is capable of monitoring large amounts of cells without harming the overall culture.

  3. Master's Degree Program in Scientific and Cultural Communication: Preliminary reports on an innovative experience in Brazil (Portuguese original version

    Directory of Open Access Journals (Sweden)

    Carlos A. Vogt

    2009-03-01

    Full Text Available The multidisiciplinary Master’s Degree Program in Scientific and Cultural Communication (MDCC began in the first semester of 2007. It is offered by the Laboratory of Advanced Studies in Journalism (Labjor of the Creativity Development Nucleus (NUDECRI and by the Institute of Language Studies (IEL, both of which are entities the State University of Campinas (UNICAMP. The program is also supported by the Department of Scientific and Technological Policy (DPCT of the Geosciences Institute (IG and by MediaTec – Media and Communication Technologies Laboratory of the Multimedia Department (DMM of the Art Institute (IA. The objective of the MDCC is to train and enable researchers with in-depth theoretical knowledge about current questions related to science communication. A global vision of the systems of science and technology are joined together with an understanding of a solid, contemporary literary and cultural repertoire. The interaction among subjects offered in the MDCC seeks to provide an education that allows critical reflection about the main accomplishments of science, technology and culture in our current society and the way in which the mass or specialized media have worked in order to communicate these accomplishments. The areas of research focus on the analysis of cultural production and science communication within the most diverse means of information, such as print, radio, television and electronic media. There is a special emphasis on areas such as science and technical history and the sociology of science, as well as other spaces of science and cultural communication, such as museums, forums and events.

  4. Evaluation of a Video-Based Seminar to Raise Health Care Professionals' Awareness of Culturally Sensitive End-of-Life Care.

    Science.gov (United States)

    Cruz-Oliver, Dulce M; Malmstrom, Theodore K; Roegner, Michael; Yeo, Gwen

    2017-07-15

    Health care workers serve diverse communities and face challenges in delivering culturally responsive EOL care, especially when caring for Latino elders. The objective of this study was to investigate the effect of a newly developed telenovela, or video soap opera, on health care professionals (HCPs)' awareness of caregivers' stress and patients' cultural approaches to end-of-life (EOL) care decisions. A multicenter cross-sectional study among three communities in New York, Miami, and Missouri. Participants from a convenience sample of multidisciplinary HCPs were randomly assigned to view power point presentation with either a control video or an intervention-telenovela about caregiving as part of a one-hour audiovisual seminar and completed a pre- and post-test questionnaire to evaluate reaction and learning. Participants (N = 142) were mostly female (80%) nurses (54%) with a mean age of 44.5 ± 12.4 years and from non-Hispanic white (41%) or Hispanics (37%) ethnicity. In both control and intervention groups, post-test responses demonstrated a high level (87%) of satisfaction with seminar and an increase in openness to discuss EOL issues with culturally diverse patients (P educate HCPs on cultural sensitivity to help ethnically diverse caregivers and their patients benefit from EOL care. Copyright © 2017. Published by Elsevier Inc.

  5. Examining the cross-cultural sensitivity of the Revised Two-Factor Study Process Questionnaire (R-SPQ-2F and validation of a Dutch version.

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    Ann Stes

    Full Text Available The Revised Two-Factor Study Process Questionnaire (R-SPQ-2F is used to examine students' study approaches in higher education. The questionnaire assumes to measure two factors: a deep and a surface study approach. Analyses into the validity and reliability of the original English R-SPQ-2F yielded positive results. In this study, we examined the degree to which these positive results can also be found for the Dutch version that we developed. By comparing our results with the results of earlier studies in different cultures, we conclude cross-cultural sensitivity is an important point to be borne in mind when using the R-SPQ-2F. Our research supports the validity and reliability of our Dutch version of the R-SPQ-2F.

  6. PEACE CULTURE IN PROGRAMS OF SOCIAL COMMUNICATION SCHOOLS OF ZULIA STATE

    OpenAIRE

    Luisa Julieta Barboza; Rocío Belandria

    2012-01-01

    This paper to search the principles for the culture of peace present in the Curriculum of the Schools of Social Communication of Zulia state. We studied the curriculum of two schools of social communication more Zulia state tuition. The study was descriptive, not experimental and transversal. A checklist was used to support a content analysis. The results showed a favorable trend for the consideration of the principles of culture of peace in the curriculum of schools of social communication i...

  7. pH-sensitivity of YFP provides an intracellular indicator of programmed cell death

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    Purcel Sydney B

    2010-11-01

    Full Text Available Abstract Background Programmed cell death (PCD is an essential process for the life cycle of all multicellular organisms. In higher plants however, relatively little is known about the cascade of genes and signalling molecules responsible for the initiation and execution of PCD. To aid with the discovery and analysis of plant PCD regulators, we have designed a novel cell death assay based on low cytosolic pH as a marker of PCD. Results The acidification that occurs in the cytosol during plant PCD was monitored by way of the extinction of YFP fluorescence at low pH. This fluorescence was recovered experimentally when bringing the intracellular pH back to 7, demonstrating that there was no protein degradation of YFP. Because it uses YFP, the assay is none-destructive, does not interfere with the PCD process and allows time-lapse studies to be carried out. In addition, changes of sub-cellular localisation can be visualised during PCD using the protein of interest fused to RFP. Coupled to a transient expression system, this pH-based assay can be used to functionally analyse genes involved in PCD, using point mutations or co-expressing PCD regulators. Transfecting mBAX and AtBI-1in onion epidermal cells showed that the pH shift is downstream of PCD suppression by AtBI-1. In addition, this method can be used to score PCD in tissues of stably transformed transgenic lines. As proof of principle, we show the example of YFP extinction during xylogenesis in Arabidopsis. This demonstrates that the assay is applicable to PCD studies in a variety of tissues. Conclusions The observation that YFP fluorescence is lost during the plant PCD process provides a new tool to study the genetic regulation and cell biology of the process. In addition, plant cell biologists should make a note of this effect of PCD on YFP fluorescence to avoid misinterpretation of their data and to select a pH insensitive reporter if appropriate. This method represents an efficient and

  8. NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience.

    Science.gov (United States)

    Singh-Taylor, A; Molet, J; Jiang, S; Korosi, A; Bolton, J L; Noam, Y; Simeone, K; Cope, J; Chen, Y; Mortazavi, A; Baram, T Z

    2017-01-10

    Resilience to stress-related emotional disorders is governed in part by early-life experiences. Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, which takes place through modification of neuronal gene expression via epigenetic mechanisms. Specifically, we found that augmented maternal care reduced glutamatergic synapses onto stress-sensitive hypothalamic neurons and repressed expression of the stress-responsive gene, Crh. In hypothalamus in vitro, reduced glutamatergic neurotransmission recapitulated the repressive effects of augmented maternal care on Crh, and this required recruitment of the transcriptional repressor repressor element-1 silencing transcription factor/neuron restrictive silencing factor (NRSF). Increased NRSF binding to chromatin was accompanied by sequential repressive epigenetic changes which outlasted NRSF binding. chromatin immunoprecipitation-seq analyses of NRSF targets identified gene networks that, in addition to Crh, likely contributed to the augmented care-induced phenotype, including diminished depression-like and anxiety-like behaviors. Together, we believe these findings provide the first causal link between enriched neonatal experience, synaptic refinement and induction of epigenetic processes within specific neurons. They uncover a novel mechanistic pathway from neonatal environment to emotional resilience.Molecular Psychiatry advance online publication, 10 January 2017; doi:10.1038/mp.2016.240.

  9. Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS.

    Science.gov (United States)

    Cardoso, Rodolfo C; Burns, Ashleigh; Moeller, Jacob; Skinner, Donal C; Padmanabhan, Vasantha

    2016-12-01

    Prenatal testosterone (T) treatment recapitulates the reproductive and metabolic phenotypes of polycystic ovary syndrome in female sheep. At the neuroendocrine level, prenatal T treatment results in disrupted steroid feedback on gonadotropin release, increased pituitary sensitivity to GnRH, and subsequent LH hypersecretion. Because prenatal T-treated sheep manifest functional hyperandrogenism and hyperinsulinemia, gonadal steroids and/or insulin may play a role in programming and/or maintaining these neuroendocrine defects. Here, we investigated the effects of prenatal and postnatal treatments with an androgen antagonist (flutamide [F]) or an insulin sensitizer (rosiglitazone [R]) on GnRH-stimulated LH secretion in prenatal T-treated sheep. As expected, prenatal T treatment increased the pituitary responsiveness to GnRH leading to LH hypersecretion. Neither prenatal interventions nor postnatal F treatment normalized the GnRH-stimulated LH secretion. Conversely, postnatal R treatment completely normalized the GnRH-stimulated LH secretion. At the tissue level, gestational T increased pituitary LHβ, androgen receptor, and insulin receptor-β, whereas it reduced estrogen receptor (ER)α protein levels. Although postnatal F normalized pituitary androgen receptor and insulin receptor-β, it failed to prevent an increase in LHβ expression. Contrarily, postnatal R treatment restored ERα and partially normalized LHβ pituitary levels. Immunohistochemical findings confirmed changes in pituitary ERα expression to be specific to gonadotropes. In conclusion, these findings indicate that increased pituitary responsiveness to GnRH in prenatal T-treated sheep is likely a function of reduced peripheral insulin sensitivity. Moreover, results suggest that restoration of ERα levels in the pituitary may be one mechanism by which R prevents GnRH-stimulated LH hypersecretion in this sheep model of polycystic ovary syndrome-like phenotype.

  10. The Role of National Culture in Advertising’s Sensitivity to Business Cycles: An Investigation Across All Continents

    NARCIS (Netherlands)

    B. Deleersnyder (Barbara); M.G. Dekimpe (Marnik); J-B.E.M. Steenkamp (Jan-Benedict); P.S.H. Leeflang (Peter)

    2007-01-01

    textabstractCutting advertising budgets has traditionally been a popular reaction by companies around the globe when faced with a slacking economy. Still, anecdotal evidence suggests the presence of considerable cross-country variability in the cyclical sensitivity of advertising expenditures. We co

  11. Sensitive method for detecting low numbers of verotoxin-producing Escherichia coli in mixed cultures by use of colony sweeps and polymyxin extraction of verotoxin.

    Science.gov (United States)

    Karmali, M A; Petric, M; Lim, C; Cheung, R; Arbus, G S

    1985-01-01

    High titers of Verotoxin (VT) were released from cell pellets of VT-producing Escherichia coli (VTEC; corresponding to E. coli strains producing "high" levels of Shiga-like toxin) after incubation in polymyxin B (0.1 mg/ml) for 30 min at 37 degrees C. Maximal titers of polymyxin-releasable VT occurred in cells obtained from 5-h Penassay broth cultures and were up to eightfold higher than the peak culture supernatant VT titers which occurred in 8-h cultures. Polymyxin-releasable cell extracts of 5-h broth cultures inoculated with mixtures of VT-positive (VT+) and VT-negative strains had easily detectable VT titers when the proportion of VT+ cells in the mixture was about 1.0%, but culture supernatants were negative for VT even when this proportion was 20%. The results were the same whether the initial inoculum consisted of broth culture mixtures of VT+ and VT-negative strains or colony sweeps (loopfuls of confluent bacterial growth) taken from solid plate media previously inoculated with the broth mixtures. In a clinical study, 80 stool cultures from patients with hemolytic uremic syndrome and family contacts with diarrhea were tested for free fecal VT, VT in polymyxin extracts of colony sweeps (VT/PECS), and VTEC (examination of 20 separate E. coli colonies from primary media for VT production). Of the 80 samples, 40 were positive for at least one of these three tests; all 40 were positive for free fecal VT, and 20 of these were positive for VT/PECS. VTEC (as few as 1 colony out of 20) were only isolated from 14 of the 20 cultures that were positive for VT/PECS. In six cases, the VT/PECS was positive even when none of 20 colonies tested were VT+, suggesting that the procedure was able to detect a proportion of VTEC that was less than one in 20(5%). We conclude that the VT/PECS method is highly sensitive for detecting low concentrations of VTEC in stools and provides a rapid method for screening out stools that are negative for VTEC. The technique should also be of

  12. Effects of a Worksite Supervised Adapted Physical Activity Program on Trunk Muscle Endurance, Flexibility, and Pain Sensitivity Among Vineyard Workers.

    Science.gov (United States)

    Balaguier, Romain; Madeleine, Pascal; Rose-Dulcina, Kévin; Vuillerme, Nicolas

    2017-01-01

    In viticulture, the prevalence of low back pain is particularly high among vineyard workers exposed to sustained and awkward postures. One promising setting for low back pain prevention resides in the implementation of workplace physical activity. This nonrandomized pilot study aims at evaluating the effects of a worksite supervised adapted physical activity program among 17 vineyard workers volunteered to enter either an intervention group (n = 10) or a control group (n = 7).The intervention group followed a physical activity program for 8 weeks involving (1) 15 minutes of warm-up every working day and (2) two weekly 1-hour adapted physical activity sessions targeting trunk muscle endurance and flexibility. The control group was advised to continue normal physical activity. Evaluations were carried out at weeks 0, 4, 8, and 12. Physical capacity was assessed using flexibility tests for the trunk, along with trunk muscle flexor and extensor endurance tests. Finally, pain sensitivity was evaluated by assessing pressure pain thresholds over 14 anatomical locations in the low back region. For the intervention group, the endurance of the trunk extensor and flexor significantly increased from baseline to week 8 as well as the pressure pain thresholds. No change was observed for the control group over the same period. These encouraging results in combination with the high adherence rate set interesting foundations for the promotion of worksite supervised adapted physical activity and, most likely, offer a new promising approach to prevent low back pain among vineyard workers.

  13. Dental school deans' perceptions of the organizational culture and impact of the ELAM program on the culture and advancement of women faculty.

    Science.gov (United States)

    Dannels, Sharon A; McLaughlin, Jean M; Gleason, Katharine A; Dolan, Teresa A; McDade, Sharon A; Richman, Rosalyn C; Morahan, Page S

    2009-06-01

    In 2006, deans of the sixty-four U.S. and Canadian dental schools were surveyed to gain their perspectives on their institutions' organizational culture for faculty, family-friendly policies, processes used by deans to develop faculty leadership, and the impact of the Executive Leadership in Academic Medicine (ELAM) Program for Women. The deans reported (52 percent response rate) an improved climate in terms of gender equity, yet recognized that inequities still exist. Of fifteen family-friendly policies, only three were available at more than 50 percent of the schools, with little indication that additional policies were under consideration. The deans reported active engagement in behaviors to develop the leadership of their faculty members. Of the nine processes, 50 percent of the deans indicated three they believed to be particularly effective with women. They agreed that ELAM has had a positive impact on their alumnae and their schools. Results are discussed in terms of how the deans' perceptions compare to faculty perceptions and within the larger context of higher education and other organizations. The responsibility of the dean to shape the dental school's culture, particularly in the face of the changing demographics of dental faculty, adds to the importance of the unique perspective provided by the deans.

  14. Adult-onset obesity reveals prenatal programming of glucose-insulin sensitivity in male sheep nutrient restricted during late gestation.

    Directory of Open Access Journals (Sweden)

    Philip Rhodes

    Full Text Available BACKGROUND: Obesity invokes a range of metabolic disturbances, but the transition from a poor to excessive nutritional environment may exacerbate adult metabolic dysfunction. The current study investigated global maternal nutrient restriction during early or late gestation on glucose tolerance and insulin sensitivity in the adult offspring when lean and obese. METHODS/PRINCIPAL FINDINGS: Pregnant sheep received adequate (1.0M; CE, n = 6 or energy restricted (0.7M diet during early (1-65 days; LEE, n = 6 or late (65-128 days; LEL, n = 7 gestation (term approximately 147 days. Subsequent offspring remained on pasture until 1.5 years when all received glucose and insulin tolerance tests (GTT & ITT and body composition determination by dual energy x-ray absorptiometry (DXA. All animals were then exposed to an obesogenic environment for 6-7 months and all protocols repeated. Prenatal dietary treatment had no effect on birth weight or on metabolic endpoints when animals were 'lean' (1.5 years. Obesity revealed generalised metabolic 'inflexibility' and insulin resistance; characterised by blunted excursions of plasma NEFA and increased insulin(AUC (from 133 to 341 [s.e.d. 26] ng.ml(-1.120 mins during a GTT, respectively. For LEL vs. CE, the peak in plasma insulin when obese was greater (7.8 vs. 4.7 [s.e.d. 1.1] ng.ml(-1 and was exacerbated by offspring sex (i.e. 9.8 vs. 4.4 [s.e.d. 1.16] ng.ml(-1; LEL male vs. CE male, respectively. Acquisition of obesity also significantly influenced the plasma lipid and protein profile to suggest, overall, greater net lipogenesis and reduced protein metabolism. CONCLUSIONS: This study indicates generalised metabolic dysfunction with adult-onset obesity which also exacerbates and 'reveals' programming of glucose-insulin sensitivity in male offspring prenatally exposed to maternal undernutrition during late gestation. Taken together, the data suggest that metabolic function appears little compromised in young

  15. Process and Product in Cross-Cultural Treatment Research: Development of a Culturally Sensitive Women-Centered Substance Use Intervention in Georgia

    Directory of Open Access Journals (Sweden)

    Hendrée E. Jones

    2014-01-01

    Full Text Available Women who inject drugs (WID are highly marginalized and stigmatized and experience ongoing discrimination in Georgia. Few opportunities exist for WID to receive publicly funded treatment for substance use disorders. The IMEDI (Investigating Methods for Enhancing Development in Individuals project was developed in response to the need for women-specific and women-centered treatment services. This paper described our approach to understanding the Georgian culture—and WID within that culture—so that we could integrate two interventions for substance use found effective in other Western and non-Western cultures and to outline how we refined and adapted our integrated intervention to yield a comprehensive women-centered intervention for substance use. Reinforcement Based Treatment (RBT and the Women’s CoOp (WC were adapted and refined based on in-depth interviews with WID (N=55 and providers of health services (N=34 to such women and focus groups [2 with WID (N=15 and 2 with health service providers (N=12]. The resulting comprehensive women-centered intervention, RBT+WC, was then pretested and further refined in a sample of 20 WID. Results indicated positive pre-post changes in urine screening results and perceived needs for both RBT+WC and a case management control condition. The approach to treatment adaptation and the revised elements of RBT+WC are presented and discussed.

  16. Cultural hegemony? Educators’ perspectives on facilitating cross-cultural dialogue

    Science.gov (United States)

    Zaidi, Zareen; Verstegen, Daniëlle; Vyas, Rashmi; Hamed, Omayma; Dornan, Tim; Morahan, Page

    2016-01-01

    Background We live in an age when education is being internationalized. This can confront students with ‘cultural hegemony’ that can result from the unequal distribution of power and privilege in global society. The name that is given to awareness of social inequality is ‘critical consciousness’. Cross-cultural dialogue provides an opportunity for learners to develop critical consciousness to counter cultural hegemony. The purpose of this research was to understand how learners engage with cross-cultural dialogue, so we can help them do so more effectively in the future. Method The setting for this research was an online discussion in an international health professions educator fellowship program. We introduced scenarios with cultural references to study the reaction of participants to cultural conversation cues. We used an inductive thematic analysis to explore power and hegemony issues. Results Participants reflected that personally they were more likely to take part in cross-cultural discussions if they recognized the context discussed or had prior exposure to educational settings with cultural diversity. They identified barriers as lack of skills in facilitating cross-cultural discussions and fear of offending others. They suggested deliberately introducing cultural issues throughout the curriculum. Conclusion Our results indicate that developing critical consciousness and cross-cultural competency will require instructional design to identify longitudinal opportunities to bring up cross-cultural issues, and training facilitators to foster cross-cultural discussions by asking clarifying questions and navigating crucial/sensitive conversations. PMID:27890048

  17. Cultural hegemony? Educators’ perspectives on facilitating cross-cultural dialogue

    Directory of Open Access Journals (Sweden)

    Zareen Zaidi

    2016-11-01

    Full Text Available Background: We live in an age when education is being internationalized. This can confront students with ‘cultural hegemony’ that can result from the unequal distribution of power and privilege in global society. The name that is given to awareness of social inequality is ‘critical consciousness’. Cross-cultural dialogue provides an opportunity for learners to develop critical consciousness to counter cultural hegemony. The purpose of this research was to understand how learners engage with cross-cultural dialogue, so we can help them do so more effectively in the future. Method: The setting for this research was an online discussion in an international health professions educator fellowship program. We introduced scenarios with cultural references to study the reaction of participants to cultural conversation cues. We used an inductive thematic analysis to explore power and hegemony issues. Results: Participants reflected that personally they were more likely to take part in cross-cultural discussions if they recognized the context discussed or had prior exposure to educational settings with cultural diversity. They identified barriers as lack of skills in facilitating cross-cultural discussions and fear of offending others. They suggested deliberately introducing cultural issues throughout the curriculum. Conclusion: Our results indicate that developing critical consciousness and cross-cultural competency will require instructional design to identify longitudinal opportunities to bring up cross-cultural issues, and training facilitators to foster cross-cultural discussions by asking clarifying questions and navigating crucial/sensitive conversations.

  18. Review of the cultural safety of a national Indigenous point-of-care testing program for diabetes management.

    Science.gov (United States)

    Shephard, Mark; O'Brien, Christopher; Burgoyne, Anthony; Croft, Jody; Garlett, Trevor; Barancek, Kristina; Halls, Heather; McAteer, Bridgit; Motta, Lara; Shephard, Anne

    2016-01-01

    In Australia, Aboriginal and Torres Strait Islander people have approximately three-fold higher rates of diabetes than non-Indigenous Australians. Point-of-care testing, where pathology tests are conducted close to the patient, with results available during the patient consultation, can potentially deliver several benefits for both the Indigenous client and the health professional team involved in their care. Currently, point-of-care testing for diabetes management is being conducted in over 180 Aboriginal and Torres Strait Islander Medical Services as part of a national program called Quality Assurance for Aboriginal and Torres Strait Islander Medical Services (QAAMS). The cultural safety of the Program was reviewed by sourcing the views of the QAAMS Indigenous Leaders Team in a focus group setting and by surveying the point-of-care testing operators enrolled in QAAMS, via an electronic questionnaire. The current study confirms that QAAMS remains a culturally safe program that fills a permanent and positive niche within the Indigenous health sector. The study demonstrates that QAAMS provides a convenient and accessible 'one-stop' pathology service for Indigenous clients with diabetes and empowers Aboriginal Health Workers to have a direct role in the care of their diabetes clients.

  19. Short-Term Faculty-Led Study Abroad Programs Enhance Cultural Exchange and Self-Awareness

    Science.gov (United States)

    Gaia, A. Celeste

    2015-01-01

    Though many experts argue that semester or year abroad study is the optimal path, short-term programs meet the needs of students who would not otherwise study abroad and can be effective at increasing intercultural competency. The present study describes one type of short-term program--the embedded faculty-led model--and provides evidence that…

  20. Socio-Cultural Influences in Eating Disorders: Focus on Sports/Fitness Program.

    Science.gov (United States)

    Moriarty, Dick; Moriarty, Mary

    This report notes that eating disorders are frequently described as a diet and fitness program gone wild. It outlines and describes five sociocultural influences which have been identified for eating disorders: (1) emphasis on thinness; (2) glorification of youth; (3) changing roles of women; (4) emphasis on fitness and sport programs; and (5) the…

  1. Building a Cross-Cultural Community through a Dual Language Immersion Program

    Science.gov (United States)

    Hood, Sally

    2011-01-01

    This research study evaluates the effectiveness of a Spanish-English dual language immersion (DLI) program. Many researchers have found that high-quality and long-term DLI programs promote academic achievement and high levels of language proficiency for both language groups. Despite the evidence, leaders from the field of bilingual education have…

  2. An Appreciative Inquiry Approach to Evaluating Culture, Structure, and Power in Agricultural Teacher Education Program Reform

    Science.gov (United States)

    Anderson, James C., II.; Thorson, Candi J.; Kelinsky, Lia R.

    2016-01-01

    This case study outlines an appreciative inquiry approach to program reform using an agricultural teacher education program at a land-grant university that had begun to suffer from a large decline in student enrollment. Documents were analyzed that provided recommendations toward a master plan for reform made by 23 key agents based on their…

  3. Creating a Culture of Success: Using the Magnet Recognition Program® as a Framework to Engage Nurses in an Australian Healthcare Facility.

    Science.gov (United States)

    Moss, Sandra; Mitchell, Marion; Casey, Veronica

    2017-02-01

    An organizational culture that reflects distrust, fear of reprisal, reluctance to challenge the status quo, acceptance of poor practice, denial, and lack of accountability creates significant issues in healthcare in relation to employee retention, burnout, organizational commitment, and patient safety. Changing culture is one of the most challenging endeavors an organization will encounter. We highlight that the Magnet Recognition Program® can be implemented as an organizational intervention to positively impact on nursing workplace culture in an international healthcare facility.

  4. The transition to medication adoption in publicly funded substance use disorder treatment programs: organizational structure, culture, and resources.

    Science.gov (United States)

    Knudsen, Hannah K; Roman, Paul M

    2014-05-01

    Medications for the treatment of substance use disorders (SUDs) are not widely available in publicly funded SUD treatment programs. Few studies have drawn on longitudinal data to examine the organizational characteristics associated with programs transitioning from not delivering any pharmacotherapy to adopting at least one SUD medication. Using two waves of panel longitudinal data collected over a 5-year period, we measured the transition to medication adoption in a cohort of 190 publicly funded treatment organizations that offered no SUD medications at baseline. Independent variables included organizational characteristics, medical resources, funding, treatment culture, and detailing activities by pharmaceutical companies. Of 190 programs not offering SUD pharmacotherapy at baseline, 22.6% transitioned to offering at least one SUD medication at follow-up approximately 5 years later. Multivariate logistic regression results indicated that the employment of at least one physician at baseline, having a greater proportion of Medicaid clients, and pharmaceutical detailing were positively associated with medication adoption. Adoption of pharmacotherapy was more likely in programs that had greater medical resources, Medicaid funding, and contact with pharmaceutical companies. Given the potential expansion of Medicaid under the Affordable Care Act, patients served by publicly funded programs may gain greater access to such treatments, but research is needed to document health reform's impact on this sector of the treatment system.

  5. A Comparative Analysis of General Culture Courses within the Scope of Knowledge Categories in Undergraduate Teacher Education Programs "Turkey and the USA"

    Science.gov (United States)

    Hayirsever, Fahriye; Kalayci, Nurdan

    2017-01-01

    In this study, general culture and general education courses within the scope of knowledge categories in undergraduate teacher education programs in Turkey and the USA are comparatively analyzed. The study is a comparative education study and uses a descriptive model. In the study, the general culture - general education courses taught in the…

  6. Improving School Climate through Sensitivity Training: Integration of a Minority Population into a Predominately White School Culture

    Science.gov (United States)

    Genco, Stephen H.

    2010-01-01

    Educators must take a critical look at all factors that may affect student outcomes. The No Child Left Behind Legislation (NCLB) was proposed to help ensure that all students have fair and equal access to educational programming. It is important for secondary school educators to be aware of environmental factors that may inhibit student success.…

  7. PEACE CULTURE IN PROGRAMS OF SOCIAL COMMUNICATION SCHOOLS OF ZULIA STATE

    Directory of Open Access Journals (Sweden)

    Luisa Julieta Barboza

    2012-11-01

    Full Text Available This paper to search the principles for the culture of peace present in the Curriculum of the Schools of Social Communication of Zulia state. We studied the curriculum of two schools of social communication more Zulia state tuition. The study was descriptive, not experimental and transversal. A checklist was used to support a content analysis. The results showed a favorable trend for the consideration of the principles of culture of peace in the curriculum of schools of social communication in Zulia State.

  8. Comparison of Assays for Sensitive and Reproducible Detection of Cell Culture-Infectious Cryptosporidium parvum and Cryptosporidium hominis in Drinking Water

    Science.gov (United States)

    Di Giovanni, George D.; Rochelle, Paul A.

    2012-01-01

    This study compared the three most commonly used assays for detecting Cryptosporidium sp. infections in cell culture: immunofluorescent antibody and microscopy assay (IFA), PCR targeting Cryptosporidium sp.-specific DNA, and reverse transcriptase PCR (RT-PCR) targeting Cryptosporidium sp.-specific mRNA. Monolayers of HCT-8 cells, grown in 8-well chamber slides or 96-well plates, were inoculated with a variety of viable and inactivated oocysts to assess assay performance. All assays detected infection with low doses of flow cytometry-enumerated Cryptosporidium parvum oocysts, including infection with one oocyst and three oocysts. All methods also detected infection with Cryptosporidium hominis. The RT-PCR assay, IFA, and PCR assay detected infection in 23%, 25%, and 51% of monolayers inoculated with three C. parvum oocysts and 10%, 9%, and 16% of monolayers inoculated with one oocyst, respectively. The PCR assay was the most sensitive, but it had the highest frequency of false positives with mock-infected cells and inactivated oocysts. IFA was the only infection detection assay that did not produce false positives with mock-infected monolayers. IFA was also the only assay that detected infections in all experiments with spiked oocysts recovered from Envirochek capsules following filtration of 1,000 liters of treated water. Consequently, cell culture with IFA detection is the most appropriate method for routine and sensitive detection of infectious Cryptosporidium parvum and Cryptosporidium hominis in drinking water. PMID:22038611

  9. The implementation and assessment of a quality and safety culture education program in a large radiation oncology department.

    Science.gov (United States)

    Woodhouse, Kristina D; Volz, Edna; Bellerive, Marc; Bergendahl, Howard W; Gabriel, Peter E; Maity, Amit; Hahn, Stephen M; Vapiwala, Neha

    2016-01-01

    In 2010, the American Society for Radiation Oncology launched a national campaign to improve patient safety in radiation therapy. One recommendation included the expansion of educational programs dedicated to quality and safety. We subsequently implemented a quality and safety culture education program (Q-SCEP) in our large radiation oncology department. The purpose of this study is to describe the design, implementation, and impact of this Q-SCEP. In 2010, we instituted a comprehensive Q-SCEP, consisting of a longitudinal series of lectures, meetings, and interactive workshops. Participation was mandatory for all department members across all network locations. Electronic surveys were administered to assess employee engagement, knowledge retention, preferred learning styles, and the program's overall impact. The Agency for Healthcare Research and Quality (AHRQ) Survey on Patient Safety Culture was administered. Analysis of variance was used for statistical analysis. Between 2010 and 2015, 100% of targeted staff participated in Q-SCEP. Thirty-three percent (132 of 400) and 30% (136 of 450) responded to surveys in 2012 and 2014, respectively. Mean scores improved from 73% to 89% (P safety culture education was critical to performing their jobs well. Full course compliance was achieved despite the sizable number of personnel and treatment centers. Periodic assessments demonstrated high knowledge retention, which significantly improved over time in nearly all department divisions. Additionally, our AHRQ patient safety grade remains high and continues to improve. These results will be used to further enhance ongoing internal safety initiatives and to inform future innovative efforts. Copyright © 2016 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

  10. Using a wellness program to promote a culture of breastfeeding in the workplace: Oregon Health & Science University's experience.

    Science.gov (United States)

    Magner, Antoinette; Phillipi, Carrie Anne

    2015-02-01

    In the United States, many women stop breastfeeding within the first month that they return to work. Working mothers experience challenges in maintaining milk supply and finding the time and space to express breast milk or feed their babies in workplace settings. Changing attitudes and culture within the workplace may be accomplished in conjunction with ensuring compliance with state and federal laws regarding breastfeeding to improve breastfeeding rates after return to work. Employee wellness programs can be 1 avenue to promote breastfeeding and human milk donation as healthy behaviors. © The Author(s) 2014.

  11. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    The Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, manages archaeological resources on the Savannah River Site (SRS). An ongoing research program provides the theoretical, methodological, and empirical basis for assessing site significance within the compliance process specified by law. The SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research, and public education activities of the SRARP during Fiscal Year 1994.

  12. Culture-Based Considerations in Programming for Stuttering Intervention with African American Clients and Their Families.

    Science.gov (United States)

    Robinson, Tommie L., Jr.; Crowe, Thomas A.

    1998-01-01

    Describes a clinical service delivery model for use with African-American children who stutter and their families. The model emphasizes the clinical importance of culture-based factors such as myths, oral presentation styles, narrative discourse styles, and cognitive learning styles, as well as rules for interaction and turn-taking. (Author/DB)

  13. Energizing corporate culture and creating competitive advantage: a new look at workforce programs.

    Science.gov (United States)

    O'Daniell, E E

    1999-01-01

    Beliefs about the best ways to attract and retain employees--and keep them continuously motivated and productive--have shifted considerably in recent years. Structural changes wrought by the "3 Rs"--restructuring, rightsizing and reengineering--have given way to organizational changes caused by the "3 Cs"--culture, communication and competencies.

  14. Teaching Respect for Cultural Diversity in Australian Early Childhood Programs: A Challenge for Professional Learning

    Science.gov (United States)

    MacNaughton, Glenda; Hughes, Patrick

    2007-01-01

    Early childhood teachers in Victoria, Australia face increasing cultural and "racial" diversity among the children and families with whom they work. A small-scale exploratory study found that many teachers were uncertain about how best to respond to such diversity and a mismatch between social expectations that teachers would encourage…

  15. Motivating Young Native American Students to Pursue STEM Learning through a Culturally Relevant Science Program

    Science.gov (United States)

    Stevens, Sally; Andrade, Rosi; Page, Melissa

    2016-01-01

    Data indicate that females and ethnic/race minority groups are underrepresented in the science and engineering workforce calling for innovative strategies to engage and retain them in science education and careers. This study reports on the development, delivery, and outcomes of a culturally driven science, technology, engineering, mathematics…

  16. Culturally sensitive adaptation of the concept of relational communication therapy as a support to language development: An exploratory study in collaboration with a Tanzanian orphanage.

    Science.gov (United States)

    Schütte, Ulrike

    2016-11-07

    Orphans and other vulnerable children (OVC) who grow up in institutional care often show communication and language problems. The caregivers lack training, and there are few language didactics programmes aimed at supporting communication and language development in OVC in institutional care in Tanzania. The purpose of the study was to adapt the German concept of relational communication therapy (RCT) as a support to language development in a Tanzanian early childhood education context in a culturally sensitive way. Following the adaptation of the concept, a training programme for Tanzanian caregiver students was developed to compare their competencies in language didactics before and after training. A convergent mixed methods design was used to examine changes following training in 12 participating caregiver students in a Tanzanian orphanage. The competencies in relational language didactics were assessed by a self-developed test and video recordings before and after intervention. Based on the results, we drew conclusions regarding necessary modifications to the training modules and to the concept of RCT. The relational didactics competencies of the caregiver students improved significantly following their training. A detailed analysis of the four training modules showed that the improvement in relational didactics competencies varied depending on the topic and the teacher. The results provide essential hints for the professionalisation of caregivers and for using the concept of RCT for OVC in institutional care in Tanzania. Training programmes and concepts should not just be transferred across different cultures, disciplines and settings; they must be adapted to the specific cultural setting.

  17. Exposure to culturally sensitive sexual health information and impact on health literacy: a qualitative study among newly arrived refugee women in Sweden.

    Science.gov (United States)

    Svensson, Pia; Carlzén, Katarina; Agardh, Anette

    2016-11-29

    In Sweden, migrants have poorer sexual and reproductive health compared to the general population. Health literacy, in the form of the cognitive and social skills enabling access to health promoting activities, is often poorer among migrants, partly due to language and cultural barriers. Culturally sensitive health education provides a strategy for enhancing health literacy. Since 2012, specially trained civic and health communicators have provided sexual and reproductive health and rights information to newly arrived refugees in Skåne, Sweden. The aim of this study was to explore how information on sexual and reproductive health and rights was perceived by female recipients and whether being exposed to such information contributed to enhanced sexual and reproductive health and rights literacy. Semi-structured in-depth interviews were conducted with nine women and analysed using qualitative content analysis. Two themes emerged: (1) opening the doors to new understandings of sexual and reproductive health and rights and (2) planting the seed for engagement in sexual and reproductive health and rights issues, illustrating how cultural norms influenced perceptions, but also how information opened up opportunities for challenging these norms. Gender-separate groups may facilitate information uptake, while discussion concerning sexual health norms may benefit from taking place in mixed groups.

  18. PPO/PEO modified hollow fiber membranes improved sensitivity of 3D cultured hepatocytes to drug toxicity via suppressing drug adsorption on membranes.

    Science.gov (United States)

    Shen, Chong; Meng, Qin; He, Wenjuan; Wang, Qichen; Zhang, Guoliang

    2014-11-01

    The three dimensional (3D) cell culture in polymer-based micro system has become a useful tool for in vitro drug discovery. Among those polymers, polysulfone hollow fiber membrane (PSf HFM) is commonly used to create a microenvironment for cells. However, the target drug may adsorb on the polymeric surface, and this elicits negative impacts on cell exposure due to the reduced effective drug concentration in culture medium. In order to reduce the drug adsorption, PSf membrane were modified with hydrophilic Pluronic (PEO-b-PPO-b-PEO) copolymers, L121, P123 and F127 (PEO contents increase from 10%, 30% to 70%), by physical adsorption. As a result, the hydrophilicity of HFMs increased at an order of PSfF127>P123>L121 HFMs. The three modified membrane all showed significant resistance to adsorption of acid/neutral drugs. More importantly, the adsorption of base drugs were largely reduced to an average value of 11% on the L121 HFM. The improved resistance to drug adsorption could be attributed to the synergy of hydrophobic/neutrally charged PPO and hydrophilic PEO. The L121 HFM was further assessed by evaluating the drug hepatotoxicity in 3D culture of hepatocytes. The base drugs, clozapine and doxorubicin, showed more sensitive hepatotoxicity on hepatocytes in L121 HFM than in PSf HFM, while the acid drug, salicylic acid, showed the similar hepatotoxicity to hepatocytes in both HFMs. Our finding suggests that PSf HFM modified by PEO-b-PPO-b-PEO copolymers can efficiently resist the drug adsorption onto polymer membrane, and consequently improve the accuracy and sensitivity of in vitro hepatotoxic drug screening.

  19. Substance Use Prevention for Urban American Indian Youth: A Efficacy Trial of the Culturally Adapted Living in 2 Worlds Program.

    Science.gov (United States)

    Kulis, Stephen S; Ayers, Stephanie L; Harthun, Mary L

    2017-04-01

    This article describes a small efficacy trial of the Living in 2 Worlds (L2W) substance use prevention curriculum, a culturally adapted version of keepin' it REAL (kiR) redesigned for urban American Indian (AI) middle school students. Focused on strengthening resiliency and AI cultural engagement, L2W teaches drug resistance skills, decision making, and culturally grounded prevention messages. Using cluster random assignment, the research team randomized three urban middle schools with enrichment classes for AI students. AI teachers of these classes delivered the L2W curriculum in two schools; the remaining school implemented kiR, unadapted, and became the comparison group. AI students (N = 107) completed a pretest questionnaire before they received the manualized curriculum lessons, and a posttest (85% completion) 1 month after the final lesson. We assessed the adapted L2W intervention, compared to kiR, with paired t tests, baseline adjusted general linear models, and effect size estimates (Cohen's d). Differences between the L2W and kiR groups reached statistically significant thresholds for four outcomes. Youth receiving L2W, compared to kiR, reported less growth in cigarette use from pretest to posttest, less frequent use of the Leave drug resistance strategy, and less loss of connections to AI spirituality and cultural traditions. For other substance use behaviors and antecedents, the direction of the non-significant effects in small sample tests was toward more positive outcomes in L2W and small to medium effect sizes. Results suggest that evidence-based substance use prevention programs that are culturally adapted for urban AI adolescents, like L2W, can be a foundation for prevention approaches to help delay initiation and slow increases in substance use. In addition to study limitations, we discuss implementation challenges in delivering school-based interventions for urban AI populations.

  20. Organizational leadership, health risk screening, individually tailored programs, and supportive workplace culture might reduce presenteeism

    NARCIS (Netherlands)

    N. Aas; W. Randi; E. Baker; E. Steultjens

    2012-01-01

    To determine if Workplace Health Promotion programs (WHPs) are effective in improving presenteeism. The secondary objective was to identify characteristics of successful programmes and potential risk factors for presenteeism. The Cochrane Library, Medline and other electronic databases were searched

  1. Fish Culture Data - Captive Broodstock Gene Rescue Program for Odd Year Class Elwha River Pink Salmon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Conduct captive brood stock gene rescue program for Elwha River odd-year class pink salmon. Raw data on rearing density, loading density, water temperature, ration,...

  2. Organizational leadership, health risk screening, individually tailored programs, and supportive workplace culture might reduce presenteeism

    NARCIS (Netherlands)

    Steultjens, Esther; Baker, E.; Aas, N.; Randi, W.

    2012-01-01

    To determine if Workplace Health Promotion programs (WHPs) are effective in improving presenteeism. The secondary objective was to identify characteristics of successful programmes and potential risk factors for presenteeism. The Cochrane Library, Medline and other electronic databases were searched

  3. Microscopy, culture, and sensitive management of uncomplicated urinary tract infections in adults in the primary care setting.

    Science.gov (United States)

    Sivathasan, Niroshan; Rakowski, Krzysztof R

    2011-06-01

    The high prevalence of urinary tract infections (UTIs) places a significant burden on healthcare systems. Clinicians may over-manage the issue, and there is great variability in practice, with economic- and resource- implications. Up to 40% of patients with a suspected UTI do not have an infection. Using PubMed (Medline) to shortlist relevant papers in English from the last 30 years, and further sub-selection to include only uncomplicated UTIs in adults in primary care, we reviewed the literature pertaining to uncomplicated UTIs, and how it should be managed efficiently in the primary care setting. In general practice, there is no advantage to routinely request microscopy and culture of urine samples in the presence of an appropriate history and urinalysis reagent-strip testing. If antibiotics are required, then a 3-day course shall suffice. Larger epidemiological studies focusing on more susceptible sub-populations may provide better guidance for discriminatory factors to produce an algorithm for treatment.

  4. The impact of religion and cultural values on AIDS education programs in Malaysia and the Philippines.

    Science.gov (United States)

    Osteria, T; Sullivan, G

    1991-01-01

    This paper examines the impact of cultural values and government policies on the content of AIDS educational literature prepared by public health agencies in Malaysia and the Philippines. The literature from these countries, which has been distributed to the public and is intended to inform them of the danger of AIDS, how the HIV is and is not transmitted, and how to avoid infection, is analyzed and evaluated for effectiveness and congruence with the dominant religious tenets and cultural practices in each country, and attitudes to sexual behavior. The paper also describes the response of these countries to the AIDS pandemic, and concludes with suggestions about how this form of AIDS education can be improved.

  5. Self-Reliability and Motivation in a Nuclear Security Culture Enhancement Program

    Energy Technology Data Exchange (ETDEWEB)

    Rogers,E.; deBoer,G.; Crawford, C.; De Castro, K.; Landers, J.

    2009-10-19

    The threat of nuclear terrorism has become a global concern. Many countries continue to make efforts to strengthen nuclear security by enhancing systems of nuclear material protection, control, and accounting (MPC&A). Though MPC&A systems can significantly upgrade nuclear security, they do not eliminate the "human factor." Gen. Eugene Habiger, a former "Assistant Secretary for Safeguards and Security" at the U.S. Department of Energy’s (DOE) nuclear-weapons complex and a former commander of U.S. strategic nuclear forces, has observed that "good security is 20% equipment and 80% people." Although eliminating the "human factor" is not possible, accounting for and mitigating the risk of the insider threat is an essential element in establishing an effective nuclear security culture. This paper will consider the organizational role in mitigating the risk associated with the malicious insider through monitoring and enhancing human reliability and motivation as well as enhancing the nuclear security culture.

  6. Students' Pre-Departure Expectations and Post-Sojourn Observations in a Short-Term International Program Abroad on the Culture, Music, and Art of Brazil

    Science.gov (United States)

    Dekaney, Elisa Macedo

    2008-01-01

    Little is known about the benefits of short-term international programs that concentrate specifically on the subject matter found in the fields of art and music. This article investigates a short-term international program that focuses on the culture, music, and art of Brazil. Findings show that students studying abroad enhance their world view…

  7. Program for developing writing skills for bilingual or socio-culturally different students

    OpenAIRE

    Slapšak, Mirjana

    2016-01-01

    In the field of education, we are being faced with a problem of teaching bilingual and socio-culturally different students, because knowing Slovenian language represents the crucial importance for their successful integration into the new environment and for their success in school. Due to the lack of understanding Slovenian language, immigrant pupils are having a hard time showing and gaining new knowledge. When communicating with their peers they are using social language whilst during clas...

  8. PROGRAMS FOR OVERCOMING THE CRISIS OF CIVILIZATION IN THE CULTURAL AND ANTHROPOLOGICAL ASPECTS

    Directory of Open Access Journals (Sweden)

    Alexei Mikhailovich VASILIEV

    2015-01-01

    Full Text Available In this article we have considered the religious culture in the Russian civilizational process, which involves studies of the main question - the question of what is existential mentality of Russian people and how it allows people to civilize in terms of the formation of the civil identity. Phil-osophical comparative studies or comparative philoso-phy is an area of historical and philosophical studies, which compares different levels of the hierarchy (con-cept, doctrine, system of the philosophical heritage of East and West, which we have tried to address in this article. Modern foreign (Western and Eastern philosoph-ical comparative studies as a relatively independent branch (direction of historical and philosophical studies and as an academic discipline is in our opinion at the stage of its institutional and conceptual formation. The relevance of this article is due to several factors, namely the crisis of European culture was perceived by Russian philosophers - representatives of Russian reli-gious Renaissance as the influence on the spiritual at-mosphere of Russian society and the mentality of Rus-sian creative intelligentsia. Was this crisis a local phe-nomenon, limited in spatial and temporal relation, typical for Western European tradition or not - that’s what we tried to reveal in this research. Russia no less than West-ern Europe, experienced acute crisis events in the first third of the XX century. In this regard (co-crisis of the epoch is obvious, the theme of the Western culture cri-sis becomes one of the central themes in the works of Russian philosophers of this period. With high probabil-ity we can say that all Russian thinkers of this time in varying degrees addressed the issue of social and cul-tural crisis in the West.

  9. Beyond Culture.

    Science.gov (United States)

    Barron, Daniel D.

    1993-01-01

    Discusses the lack of literature relating to cultural differences and school library media programs and reviews the book "Beyond Culture" by Edward T. Hall. Highlights include the population/environment crisis, cultural literacy, the use of technology, and Marshall McLuhan's idea of the global village. (LRW)

  10. Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids

    Energy Technology Data Exchange (ETDEWEB)

    Hossain, Mohammad Salim; Chowdhury, Abu Asad; Rahman, Mohammad Sharifur [Department of Life Science and Biotechnology, Shimane University, 1060 Nishikawatsu-cho, Matsue, Shimane 690-8504 (Japan); Nishimura, Kohji [Department of Molecular and Functional Genomics, Center for Integrated Research in Science, Shimane University, 1060 Nishikawatsu-cho, Matsue, Shimane 690-8504 (Japan); Jisaka, Mitsuo; Nagaya, Tsutomu [Department of Life Science and Biotechnology, Shimane University, 1060 Nishikawatsu-cho, Matsue, Shimane 690-8504 (Japan); Shono, Fumiaki [Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, 180 Yamashiro-cho, Tokushima-shi, Tokushima 770-8514 (Japan); Yokota, Kazushige, E-mail: yokotaka@life.shimane-u.ac.jp [Department of Life Science and Biotechnology, Shimane University, 1060 Nishikawatsu-cho, Matsue, Shimane 690-8504 (Japan)

    2012-02-15

    Lipocalin-type prostaglandin D synthase (L-PGDS) expressed preferentially in adipocytes is responsible for the synthesis of PGD{sub 2} and its non-enzymatic dehydration products, PGJ{sub 2} series, serving as pro-adipogenic factors. However, the role of L-PGDS in the regulation of adipogenesis is complex because of the occurrence of several derivatives from PGD{sub 2} and their distinct receptor subtypes as well as other functions such as a transporter of lipophilic molecules. To manipulate the expression levels of L-PGDS in cultured adipocytes, cultured preadipogenic 3T3-L1 cells were transfected stably with a mammalian expression vector having cDNA encoding murine L-PGDS oriented in the sense direction. The isolated cloned stable transfectants with L-PGDS expressed higher levels of the transcript and protein levels of L-PGDS, and synthesized PGD{sub 2} from exogenous arachidonic acid at significantly higher levels. By contrast, the synthesis of PGE{sub 2} remained unchanged, indicating no influence on the reactions of cyclooxygenase (COX) and PGE synthase. Furthermore, the ability of those transfectants to synthesize {Delta}{sup 12}-PGJ{sub 2} increased more greatly during the maturation phase. The sustained expression of L-PGDS in cultured stable transfectants hampered the storage of fats during the maturation phase of adipocytes, which was accompanied by the reduced gene expression of adipocyte-specific markers reflecting the down-regulation of the adipogenesis program. The suppressed adipogenesis was not rescued by either exogenous aspirin or peroxisome proliferator-activated receptor {gamma} (PPAR{gamma}) agonists including troglitazone and {Delta}{sup 12}-PGJ{sub 2}. Taken together, the results indicate the negative regulation of the adipogenesis program by the enhanced expression of L-PGDS through a cellular mechanism involving the interference of the PPAR{gamma} signaling pathway without the contribution of endogenous pro-adipogenic prostanoids

  11. Do cultural differences influence batterer intervention program outcomes? A studywith Spanish and Latin American offenders

    Directory of Open Access Journals (Sweden)

    Viviana Vargas

    2015-04-01

    Full Text Available This study analyzed, first, if there were any differences in attitudes towards partner violence (i.e., perceivedseverity, victim blaming, and acceptability, responsibility attributions, sexism, and risk of recidivismbetween Latin American immigrants and Spanish offenders convicted of intimate-partner violence at thebeginning of a batterer intervention program. Second, differences in the batterer intervention programoutcomes between Spanish and Latin American offenders were explored. The sample consisted of 278batterers (211 Spanish and 67 Latin American who participated in a community-based battererintervention program. Results showed significant differences between Spanish and Latin Americanoffenders in perceived severity, victim blaming, violence against women acceptability, and benevolentsexism. Regarding batterer intervention program outcomes, results showed that despite initial differencesbetween Spanish and Latin American offenders, both groups benefit equally from the intervention.

  12. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program: Fiscal year 1991

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Mark J.; Brooks, Richard D.; Sassaman, Kenneth E.; Crass, David C.; Stephenson, D. Keith; Green, William; Rinehart, Charles J.; Lewis, George S.; Fuglseth, Ty; Krawczynski, Keith; Warnock, D. Mark

    1991-10-01

    A cooperative agreement with the United States Department of Energy provides the necessary funding for the Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, to render services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of archaeological resources is usually determined by research potential, the SRARP is guided by research objectives. An ongoing research program provides the theoretical, methodological and empirical basis for assessing site significance within the compliance process specified by law. In accordance with the spirit of the law, the SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research and public education activities of the SRARP during Fiscal Year 1991.

  13. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program: Fiscal year 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-01

    A cooperative agreement with the United States Department of Energy provides the necessary funding for the Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, to render services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of archaeological resources is usually determined by research potential, the SRARP is guided by research objectives. An ongoing research program provides the theoretical, methodological and empirical basis for assessing site significance within the compliance process specified by law. In accordance with the spirit of the law, the SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research and public education activities of the SRARP during Fiscal Year 1991.

  14. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program, fiscal year 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-01

    The Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, is funded through a direct contract with the United States Department of Energy to provide services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of most archaeological resources is dependent upon research potential, the SRARP is guided by research objectives. An on-going research program provides the problems, methods and means of assessing site significance within the compliance process specified by law. In addition, the SRARP maintains an active program of public education to disseminate knowledge about prehistory and history, and to enhance public awareness about historic preservation. The following report summarizes the management, research and public education activities of the SRARP during Fiscal Year 1990.

  15. Annual review of cultural resource investigations by the Savannah River Archaeological Research Program. Fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-01

    A cooperative agreement with the United States Department of Energy provides the necessary funding for the Savannah River Archaeological Research Program (SRARP) of the South Carolina Institute of Archaeology and Anthropology, University of South Carolina, to render services required under federal law for the protection and management of archaeological resources on the Savannah River Site (SRS). Because the significance of archaeological resources is usually determined by research potential, the SRARP is guided by research objectives. An ongoing research program provides the theoretical, methodological, and empirical basis for assessing site significance within the compliance process specified by law. In accordance with the spirit of the law, the SRARP maintains an active public education program for disseminating knowledge about prehistory and history, and for enhancing awareness of historic preservation. This report summarizes the management, research, and public education activities of the SRARP during Fiscal Year 1993.

  16. Dynamic performance of frictionless fast shutters for ITER: Numerical and analytical sensitivity study for the development of a test program

    Energy Technology Data Exchange (ETDEWEB)

    Panin, Anatoly, E-mail: a.panin@fz-juelich.de [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany); Khovayko, Mikhail [St. Petersburg Polytechnic University, Mechanics and Control Processes Department, Computational Mechanics Laboratory, 195251 St. Petersburg (Russian Federation); Krasikov, Yury [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany); Nemov, Alexander [St. Petersburg Polytechnic University, Mechanics and Control Processes Department, Computational Mechanics Laboratory, 195251 St. Petersburg (Russian Federation); Biel, Wolfgang; Mertens, Philippe; Neubauer, Olaf; Schrader, Michael [Forschungszentrum Jülich GmbH, Institut für Energie- und Klimaforschung – Plasmaphysik, 52425 Jülich (Germany)

    2015-10-15

    To prolong a lifetime of the ITER first diagnostic mirrors some protective shutters can be engaged. A concept of an elastic shutter that operates frictionless in vacuum has been studied at the Forschungszentrum Jülich, Germany. Under actuation two shutter arms (∼2 m long) bend laterally between two pairs of limiting bumpers thus shielding the optical aperture or opening it for measurements. To increase the shutter efficiency the transition time between its open and closed states can be minimized. This demands a fast shutter that operates in fractions of a second and exhibit essentially dynamic behavior, like impacts with the bumpers that cause the shutter arms’ bouncing and oscillations. The paper presents numerical studies of the shutter dynamic behavior using the explicit and implicit 3D FE transient structural modeling. Simple 1D analytical model was developed to predict the shutter impact kinetic energy that mostly determines its further dynamic response. The structure sensitivity to different parameters was studied and ways for its optimization were laid down. A parametric shutter mockup with easily changeable mechanical characteristics was manufactured. A test program aimed for further shutter optimization, basing on the analysis performed and engaging powerful capabilities of the parametric shutter mockup is discussed in the paper.

  17. Long term culture of mesenchymal stem cells in hypoxia promotes a genetic program maintaining their undifferentiated and multipotent status

    Directory of Open Access Journals (Sweden)

    de Carvalho Marcelo

    2011-03-01

    Full Text Available Abstract Background In the bone marrow, hematopietic and mesenchymal stem cells form a unique niche in which the oxygen tension is low. Hypoxia may have a role in maintaining stem cell fate, self renewal and multipotency. However, whereas most studies addressed the effect of transient in vitro exposure of MSC to hypoxia, permanent culture under hypoxia should reflect the better physiological conditions. Results Morphologic studies, differentiation and transcriptional profiling experiments were performed on MSC cultured in normoxia (21% O2 versus hypoxia (5% O2 for up to passage 2. Cells at passage 0 and at passage 2 were compared, and those at passage 0 in hypoxia generated fewer and smaller colonies than in normoxia. In parallel, MSC displayed (>4 fold inhibition of genes involved in DNA metabolism, cell cycle progression and chromosome cohesion whereas transcripts involved in adhesion and metabolism (CD93, ESAM, VWF, PLVAP, ANGPT2, LEP, TCF1 were stimulated. Compared to normoxic cells, hypoxic cells were morphologically undifferentiated and contained less mitochondrias. After this lag phase, cells at passage 2 in hypoxia outgrew the cells cultured in normoxia and displayed an enhanced expression of genes (4-60 fold involved in extracellular matrix assembly (SMOC2, neural and muscle development (NOG, GPR56, SNTG2, LAMA and epithelial development (DMKN. This group described herein for the first time was assigned by the Gene Ontology program to "plasticity". Conclusion The duration of hypoxemia is a critical parameter in the differentiation capacity of MSC. Even in growth promoting conditions, hypoxia enhanced a genetic program that maintained the cells undifferentiated and multipotent. This condition may better reflect the in vivo gene signature of MSC, with potential implications in regenerative medicine.

  18. Delivering MBA Programs in Emerging Markets: The Challenge of National Culture

    Science.gov (United States)

    Jones, Stephanie

    2013-01-01

    Increasingly, Western-style MBA programs are being delivered in emerging markets, as the developed countries become more and more saturated with MBAs and related offerings. This article, based on the global experience of the author in teaching and assessing MBA modules including thesis and dissertation research and writing, suggests approaches to…

  19. Culture, Psychological Characteristics, and Socioeconomic Status in Educational Program Development for Native Americans.

    Science.gov (United States)

    Antell, Will

    Addressed to educators who have the responsibility for developing curriculums or educational programs that will serve Native American students, the document does not present new information on the status of education in Native American communities. Rather, it discusses ways in which available information, such as the 1928 Meriam Report, can be…

  20. Cross-Cultural Competency Adaptability of Dental Hygiene Educators in Entry Level Dental Hygiene Programs

    Science.gov (United States)

    Engeswick, Lynnette Marie

    2011-01-01

    This study was conducted to discover the extent dental hygiene educators in 25 entry-level dental hygiene programs from the Upper Midwest demonstrate Emotional Resilience, Flexibility and Openness, Perceptual Acuity, and Personal Autonomy as they relate to their level of education and multicultural experiences. An additional purpose was to examine…