Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity.

Science.gov (United States)

Nam, Ki Hyun; Kurinov, Igor; Ke, Ailong

2011-09-02

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated protein genes (cas genes) are widespread in bacteria and archaea. They form a line of RNA-based immunity to eradicate invading bacteriophages and malicious plasmids. A key molecular event during this process is the acquisition of new spacers into the CRISPR loci to guide the selective degradation of the matching foreign genetic elements. Csn2 is a Nmeni subtype-specific cas gene required for new spacer acquisition. Here we characterize the Enterococcus faecalis Csn2 protein as a double-stranded (ds-) DNA-binding protein and report its 2.7 Å tetrameric ring structure. The inner circle of the Csn2 tetrameric ring is ∼26 Å wide and populated with conserved lysine residues poised for nonspecific interactions with ds-DNA. Each Csn2 protomer contains an α/β domain and an α-helical domain; significant hinge motion was observed between these two domains. Ca(2+) was located at strategic positions in the oligomerization interface. We further showed that removal of Ca(2+) ions altered the oligomerization state of Csn2, which in turn severely decreased its affinity for ds-DNA. In summary, our results provided the first insight into the function of the Csn2 protein in CRISPR adaptation by revealing that it is a ds-DNA-binding protein functioning at the quaternary structure level and regulated by Ca(2+) ions.

Consolidation of use of the CSN-CIEMAT radiological protection educational portal; Consolidacion de la utilidad del portal educativo de proteccion radiologica CSN-Ciemat

Energy Technology Data Exchange (ETDEWEB)

Llorente Herranz, C.; Marco Arboli, M.; Fernandez Sanchez, J.; Villaroel Gonzalez-Elipe, R.

2016-05-01

he workers of nuclear and radioactive facilities are required to undertake training programmes on radiological protection in order to achieve the accreditations and licences granted by the CSN. Since 2003, the Council has been collaborating with CIEMAT in the development, maintenance and updating of the teaching material for these courses. More than a thousand such courses have been delivered to date and their contents are accessible via Internet. (Author)

Crystal Structure of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Csn2 Protein Revealed Ca[superscript 2+]-dependent Double-stranded DNA Binding Activity

Energy Technology Data Exchange (ETDEWEB)

Nam, Ki Hyun; Kurinov, Igor; Ke, Ailong (Cornell); (NWU)

2012-05-22

Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated protein genes (cas genes) are widespread in bacteria and archaea. They form a line of RNA-based immunity to eradicate invading bacteriophages and malicious plasmids. A key molecular event during this process is the acquisition of new spacers into the CRISPR loci to guide the selective degradation of the matching foreign genetic elements. Csn2 is a Nmeni subtype-specific cas gene required for new spacer acquisition. Here we characterize the Enterococcus faecalis Csn2 protein as a double-stranded (ds-) DNA-binding protein and report its 2.7 {angstrom} tetrameric ring structure. The inner circle of the Csn2 tetrameric ring is {approx}26 {angstrom} wide and populated with conserved lysine residues poised for nonspecific interactions with ds-DNA. Each Csn2 protomer contains an {alpha}/{beta} domain and an {alpha}-helical domain; significant hinge motion was observed between these two domains. Ca{sup 2+} was located at strategic positions in the oligomerization interface. We further showed that removal of Ca{sup 2+} ions altered the oligomerization state of Csn2, which in turn severely decreased its affinity for ds-DNA. In summary, our results provided the first insight into the function of the Csn2 protein in CRISPR adaptation by revealing that it is a ds-DNA-binding protein functioning at the quaternary structure level and regulated by Ca{sup 2+} ions.

The independence of the CSN and Parliamentary control

International Nuclear Information System (INIS)

Cuevas Delgado, A.

2006-01-01

The Chairman of the Congressional Commission for Industry, Tourism and commerce underlines the link between the CSN and Parliament, to which the Council is accountable via control mechanisms that have improved over the years. he also points to the fact that the obligatory compliance with the resolutions approved has implied improvements in the structure and operation of the regulator. In winding up, the trusts that the modification of the Law which the council was created will promote the independence of the organisation with respect to the legitimate interests of industry, the democratic control exercised by Parliament and transparency before the public. (Author)

Frequency and association of polymorphisms in CSN3 gene with milk yield and composition in Saanen goats/Frecuencia y asociación de polimor smos en gene CSN3 con producción y composición de la leche de cabras Saanen

Directory of Open Access Journals (Sweden)

Luis David Catota-Gómez

2017-09-01

Full Text Available K-casein (CSN3 gene is of particular interest in goat production due to the e ect of its polymorphisms on milk quality and composition. The objective of this study was to assess the genotypic and allelic frequencies in CSN3 gene in the Saanen goat breed and its e ect on milk production and some of its compositional traits. Allelic discrimination assays were designed to determine the variants (A, B or C using qPCR and allelic discrimination method. Allelic frequencies for A, B and C were 0.23, 0.64 and 0.13, respectively. Association analysis indicated that the CSN3 was signi cantly associated only with protein percentage (p = 0.006. Results indicated that animals with AC, BB and CC genotypes showed higher milk protein percentage than those with genotype AB. This evidence suggests that genotypes favorable to this associated trait could be included into Saanen goat breeding strategies.

Tratamiento de enfermedad de aorta torácica con afectación de troncos supraaórticos usando técnica combinada de cirugía convencional y tratamiento endovascular

Directory of Open Access Journals (Sweden)

Antonio Jiménez Aceituno

2007-04-01

Conclusiones: El abordaje del arco aórtico usando técnicas endovasculares presenta el problema de la oclusión de TSA. El uso de derivaciones quirúrgicas hace posible esto. El abordaje combinado es aún una técnica nueva pero que podría ser una alternativa válida a la cirugía abierta de arco y aorta torácica descendente. Nuestra experiencia es satisfactoria, aunque no concluyente por tratarse sólo de dos casos.

Genetic polymorphism of CSN1S2 in South African dairy goat ...

African Journals Online (AJOL)

The aim of this study was to investigate the polymorphism and genetic variation of CSN1S2 in South African dairy goats, using DNA sequencing technology. Sixty dairy goats (20 Saanes, 20 British Alpine, and 20 Toggenburg) and 20 meat-type goats were sequenced with four primers to distinguish among the seven known ...

Patrimonio cultural: lo intangible se hace tangible

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William Heredia Orjuela

2004-11-01

Full Text Available Se presentan tres reflexiones a manera de ensayo, elaboradas por estudiantes de vii semestre de la Facultad de Administración de Empresas Turísticas y Hoteleras. El tema central que engloba los escritos es el de la responsabilidad frente al patrimonio cultural, su valoración y su relación con el turismo. En el ensayo La protección del patrimonio cultural como reflejo del ser humano, la estudiante cecilia hinosTrosa hace un llamado de atención frente al problema del tráfico ilícito de bienes que conlleva la pérdida de testimonios de la cultura humana. El escrito de la estudiante mariel cecilia hernández destaca las bondades de recuperar las tradiciones y de cómo éstas se pueden difundir a través del turismo. Por último, el estudiante William heredia hace una reflexión sobre la tangibilidad de lo intangible, en el ensayo Patrimonio Cultural: lo tangible se hace intangible, donde destaca la declaratoria del Carnaval de Barranquilla como patrimonio oral e intangible de la humanidad.

Coordinated CSN-UNESA research plan (PCI)

International Nuclear Information System (INIS)

Incinillas, J.

2001-01-01

This article contains a description of the essence and current status of the Coordinated Research Plan (PCI), beginning with details on the general specifications of the Framework Agreement signed by CSN and UNESA in September 1997, with an initial duration of four years and extendable on a yearly basis. The section on PCI Management describes the governing bodies, the mechanisms for including a project, tracking of projects underway, and the mechanisms for concluding projects. The Plan's generic goals are to acquire and increase technological skills and tools to guarantee operation of the nuclear park, take advantage of the synergies of the plants as a whole, and optimize the regulatory framework from the standpoint of safety and efficiency. In addition, strategic targets concerning efficiency, technological development and environment are defined. The current project status, overall budget and project completed to data are described. (Author)

Consolidation of use of the CSN-CIEMAT radiological protection educational portal

International Nuclear Information System (INIS)

Llorente Herranz, C.; Marco Arboli, M.; Fernandez Sanchez, J.; Villaroel Gonzalez-Elipe, R.

2016-01-01

he workers of nuclear and radioactive facilities are required to undertake training programmes on radiological protection in order to achieve the accreditations and licences granted by the CSN. Since 2003, the Council has been collaborating with CIEMAT in the development, maintenance and updating of the teaching material for these courses. More than a thousand such courses have been delivered to date and their contents are accessible via Internet. (Author)

Expression, purification and crystallization of a PCI domain from the COP9 signalosome subunit 7 (CSN7)

International Nuclear Information System (INIS)

Dessau, Moshe; Chamovitz, Daniel A.; Hirsch, Joel A.

2006-01-01

A core fragment of Arabidopsis thaliana COP9 signalosome (CSN) subunit 7 was expressed in Escherichia coli. The protein was purified to homogeneity and crystallized. A core fragment of Arabidopsis thaliana COP9 signalosome (CSN) subunit 7 was expressed in Escherichia coli. The protein was purified to homogeneity and screened for crystallization. Crystallization conditions were refined using the sitting-drop vapour-diffusion method. Crystals were obtained using polyethylene glycol 8000 as a precipitant and have a thick rod-like morphology. Their crystallographic symmetry is orthorhombic, space group C222 1 , with unit-cell parameters a = 57.2, b = 86.2, c = 72.6 Å and a diffraction limit of 2.06 Å

Preliminary Report on CSN3 and LGB genes Polymorphism Among Two Romanian Cattle Breeds

Directory of Open Access Journals (Sweden)

Daniela Elena Ilie

2017-05-01

Full Text Available The aim of the current study was to evaluate the genetic polymorphism of A and B variants at the CSN3 (κ-casein and LGB (β-lactoglobulin loci in Romanian Spotted and Romanian Brown breeds using PCR-RFLP and PCR-HRM genotyping methods. Altogether, 280 cattle from Arad county were genotyped. The most frequent allele at the CSN3 locus was A in Romanian Spotted breed (0.723 while the B allele was the most common in the Romanian Brown (0.694. For LGB locus the A and B alleles recorded similar frequencies for Romanian Spotted (0.5141 and 0.4859 compared to Romanian Brown breed where the B allele was the most prevalent (0.5970. Knowledges regarding genetic information of breeds related to milk protein are valuable for economic reassertion of cattle breeds, particularly autochthonous ones. Further, the results would be useful in future breeding programs for the studied population, aimed to improve cattle genetic structure for milk quality traits.

Análisis de la calidad de servicio al cliente que se oferta en las agencias de registro civil de las ciudades de Riobamba, Ambato, Guaranda y Latacunga usando el modelo SERVQUAL.

OpenAIRE

Haro Sosa, Giovanny Lenin

2017-01-01

La investigación tiene por objetivo analizar la calidad de servicio al cliente que se oferta en las agencias de Registro Civil de las ciudades de Riobamba, Ambato, Guaranda y Latacunga usando el modelo SERVQUAL. Registro Civil ha implementado grandes cambios en los últimos años referente a infraestructura, innovación tecnológica y talento humano, sin embargo, de ello no existe un modelo de aseguramiento de la calidad del servicio, por lo cual se hace necesario visitar a cada un...

Genetic characterisation of CSN2 gene in Girgentana goat breed

Directory of Open Access Journals (Sweden)

Lina Tortorici

2014-12-01

Full Text Available Among calcium sensitive caseins, β-casein is the most abundant in goat milk, representing up to 50% of total casein content. The goat β-casein locus has been widely investigated and at least ten alleles have been identified in different goat breeds. The aim of this work was to investigate the polymorphisms of β-casein gene in Girgentana dairy goat breed in order to assess the genotype distribution and evaluate how frequencies have changed during the last 10 years, as genotype is known to influence technological and nutritional milk properties. Sequencing analysis and alignment of the obtained sequences of β-casein exon 7, showed the presence of C, C1, and A strong alleles, and 0' null allele, with frequencies of 0.597, 0.326, 0.023, and 0.054, respectively. Seven genotypic classes were found in Girgentana goat breed and the most frequent genotype was CC1 (0.423 followed by CC (0.326, C1C1 (0.110, and C0' (0.096. No AA nor 0'0' homozygous individuals were found. The presence of strong alleles at CSN2 gene in Girgentana goat breed could be useful for the production of milk with high protein content and good cheese-making properties. Moreover, food business operators should consider the possibility of reviving interest in Girgentana goat milk using weak and null genotypes at CSN2 locus to make peculiar food products, such as drinking milk.

Maintaining the Database for Information Object Analysis, Intent, Dissemination and Enhancement (IOAIDE) and the US Army Research Laboratory Campus Sensor Network (ARL CSN)

Science.gov (United States)

2017-01-01

operations as well as basic knowledge of Microsoft Structured Query Language Server Management Studio (2014 or 2016). 15. SUBJECT TERMS Microsoft SQL ...designed and is maintained with Microsoft SQL Server Management Studio. The basic requirements for the IOAIDE/ARL CSN database development and... SQL server (2014 or 2016) installed. All images in this report were generated using Windows 10. The IOAIDE/ARL CSN database could reside on the

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

Directory of Open Access Journals (Sweden)

Luigi Tortola

2016-05-01

Full Text Available Summary: The HECT domain E3 ligase HACE1 has been identified as a tumor suppressor in multiple cancers. Here, we report that HACE1 is a central gatekeeper of TNFR1-induced cell fate. Genetic inactivation of HACE1 inhibits TNF-stimulated NF-κB activation and TNFR1-NF-κB-dependent pathogen clearance in vivo. Moreover, TNF-induced apoptosis was impaired in hace1 mutant cells and knockout mice in vivo. Mechanistically, HACE1 is essential for the ubiquitylation of the adaptor protein TRAF2 and formation of the apoptotic caspase-8 effector complex. Intriguingly, loss of HACE1 does not impair TNFR1-mediated necroptotic cell fate via RIP1 and RIP3 kinases. Loss of HACE1 predisposes animals to colonic inflammation and carcinogenesis in vivo, which is markedly alleviated by genetic inactivation of RIP3 kinase and TNFR1. Thus, HACE1 controls TNF-elicited cell fate decisions and exerts tumor suppressor and anti-inflammatory activities via a TNFR1-RIP3 kinase-necroptosis pathway. : Tortola et al. report that the E3 ubiquitin ligase HACE1 is a gatekeeper of TNFR1-mediated cell fate. Hace1 deficiency impairs TNF-driven NF-κB activation and apoptosis and predisposes cells to necroptosis. Consequently, hace1–/– mice show enhanced colitis and colon cancer, which can be reverted by inactivation of pro-necroptotic kinase RIP3 and TNFR1.

Learning from nuclear regulatory self-assessment. International peer review of the CSN report on lessons learnt from the essential service water system degradation event at the Vandellos nuclear power plant

International Nuclear Information System (INIS)

2006-01-01

Nuclear regulatory self-assessment together with the benchmarking of regulatory practices against those of other countries operating nuclear power plants are key elements in maintaining a high level of nuclear safety. In that light, the Spanish Consejo de Seguridad Nuclear (CSN) formally asked the OECD Nuclear Energy Agency (NEA) to establish an international peer review team to assess the CSN report on the lessons learnt as a result of the 2004 Vandellos II event involving essential service water system degradation. The International Review Team considers the CSN report prepared in follow-up to the Vandellos event to be a commendable effort in regulatory self-assessment. The report, complemented by this international peer review, should enable the CSN to take appropriate action to ensure that its regulatory supervision is in line with best international practice. (authors)

Review of the Main Activities Carried out by the CSN in the Last Five Years; Revision de las principales actuaciones del CSN en los ultimos cinco anos

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

Nearing the time to finalise a new phase for the Consejo de Seguridad Nuclear, it is time to make a brief account of the main activities carried out over the past five years. During this period, one in which the CSN celebrated its 25th Anniversary, the organisation has served a social demand in a modernisation and adjustment process, followed by the continuous improvement process which throughout its history the former management, teams have carried out with great stamina and dedication. (Author)

Instruction of the CSN on the requirements of the system of management of the nuclear power plants; Instruccion del CSN sobre los requisitos del sistema de gestion de las instalaciones nucleares

Energy Technology Data Exchange (ETDEWEB)

Cid, R.; Santo, A. de; Gil Montes, B.; Toca, A.

2008-07-01

The Western European Nations Regulatory Authorities (WENRA) performed a nuclear safety requirements harmonization task, as a result of this work and its implementation, the Spanish Nuclear Safety Counsel (CSN) has the commitment to issue its own Regulation Safety Instructions) to identify the WENRA to level nuclear safety requirements, and to incorporate it in the Spanish regulatory pyramid. However, the Spain nuclear installations meet these requirements through the original criteria to fulfill the regulation of the country that supply the NSSS design, these requirements are not incorporated in our regulation. One of the issues, identified by WENRA, is the implementation of the management system requirements in accord with the IAEA GS-R-3 The Management System for Facilities and Activities. As these regards, the CSN has developed a Safety Instruction, basically endorsing the IAEA GS-R-3. The Safety Instruction is actually in a phase of external comments and should be issued by june 2008. This paper describes the bases for the Safety Instruction, summarises the requirements that would meet the management system for nuclear installations and the activities to perform for its implementations. (Author)

A Test of Reliability of the Personnel Dosimetry Services Authorized by CSN using Photon Beams

International Nuclear Information System (INIS)

Brosed, A.; Delgado, A.; Granados, C. E.; Lopez Ortiz, G.

1987-01-01

In 1987 the Consejo de Seguridad Nuclear (CSN) had eight Personnel Dosimetry Services (PDS) authorized to asses the equivalent doses to the spanish occupationally exposed workers, by means of the readings from the dosemeters wear by them. An audit was carried on the PDS on behalf of CSN under the control of CIEMAT. Batches of dosemeters from each one of the PDS were irradiated to dose equivalent values which were well established by CIEMAT but kept hidden from the PDS. By comparing the true values with those obtained by the PDS, it was possible to evaluate the Services according to the analysis of the quantity Q= I B I -I- S where B is the average of the individual deviations between the dosemeters belonging to the same group and the true value as established by CIEMAT, whereas S is the standard deviation of the values inside of this same group. The results of the evaluation, which was made using the new ICRU quantities for personnel monitoring, are presented. (Author) 8 refs

CSN-associated USP48 confers stability to nuclear NF-κB/RelA by trimming K48-linked Ub-chains.

Science.gov (United States)

Schweitzer, Katrin; Naumann, Michael

2015-02-01

Diligent balance of nuclear factor kappa B (NF-κB) activity is essential owing to NF-κB's decisive role in cellular processes including inflammation, immunity and cell survival. Ubiquitin/proteasome-system (UPS)-dependent degradation of activated NF-κB/RelA involves the cullin-RING-ubiquitin-ligase (CRL) ECS(SOCS1). The COP9 signalosome (CSN) controls ubiquitin (Ub) ligation by CRLs through the removal of the CRL-activating Ub-like modifier NEDD8 from their cullin subunits and through deubiquitinase (DUB) activity of associated DUBs. However, knowledge about DUBs involved in the regulation of NF-κB activity within the nucleus is scarce. In this study we observed that USP48, a DUB of hitherto ill-defined function identified through a siRNA screen, associates with the CSN and RelA in the nucleus. We show that USP48 trims rather than completely disassembles long K48-linked free and substrate-anchored Ub-chains, a catalytic property only shared with ataxin-3 (Atx3) and otubain-1 (OTU1), and that USP48 Ub-chain-trimming activity is regulated by casein-kinase-2 (CK2)-mediated phosphorylation in response to cytokine-stimulation. Functionally, we demonstrate for the first time the CSN and USP48 to cooperatively stabilize the nuclear pool of RelA, thereby facilitating timely induction and shutoff of NF-κB target genes. In summary, this study demonstrates that USP48, a nuclear DUB regulated by CK2, controls the UPS-dependent turnover of activated NF-κB/RelA in the nucleus together with the CSN. Thereby USP48 contributes to a timely control of immune responses. Copyright © 2014 Elsevier B.V. All rights reserved.

On the structure and variation of 'hace' as a temporal expression ...

African Journals Online (AJOL)

The goal of this article is to analyse a case of variation in Spanish. In most varieties, constructions of the form Hace dos días que (“it has been two days since”) reject nominal expressions like todo el día (“all the day”), hence *Hace todo el día que (lit. “it has been all the day that”). However, a particular variety of Argentinean ...

Ein Elefant vergißt nicht - Erweiterte Funktionen in PostgreSQL am Beispiel der CSN Datenbank

OpenAIRE

Schreiber, Daniel

2004-01-01

PostgreSQL ist eine Open Source Datenbank, die in den letzten Jahren sehr populär geworden ist. Das Chemnitzer Studentennetz benutzt seit 1999 PostgreSQL zur Verwaltung seines Netzes. Der Vortrag zeigt erweiterte Funktionen von PostgreSQL wie Views, Rules, Stored Procedures und Trigger sowie deren Verwendung in der CSN Datenbank.

Evaluation of refractory lining wear of Companhia Siderurgica Nacional (CSN) blast furnaces

International Nuclear Information System (INIS)

Santos, N.J. dos; Mello, A.H.B. de; Pereira, C.L.; Paula Sarkis, D. de; Martins Filho, D.I.; Banados Perez, H.E.; Carvalho, G.; Daltro, T.F.L.

1984-01-01

The blast furnace refractory linings are submitted to unfavourable conditions such as alkalis attack, temperature, top pressure, abrasion and so forth... After studies on distribution and installation of radioactive sources with low activities in the refractory lining, it was possible to develop a new technique of thickness evaluation and attendance of wearing in the furnace lining. The viability analysis, simulated laboratory tests, localization, identification, installations and periodical measurements of the radioactive sources are described, as well the results obtained on the present campaign of CSN Blast Furnaces. (Author) [pt

Preambolo al Catalogo Sismico Nazionale (CSN. I criteri di informazione del Catalogo Sismico Nazionale (CSN

Directory of Open Access Journals (Sweden)

M. VECCHI

1979-06-01

Full Text Available

This note presents a study meant to set out a national catalogue
(C.S.N. of seismic events the epicentres of which are to be found in
Italian territory (or nearby. The catalogue, that will start from the
year 1450 B.C., could be used for various purpose employing modern
technologies.
The complete C.S.N, is made of three main parts, each of which can
also have a separate life:
1 An Analytical Catalogue which comprises the greater part of
data and is the most complete;
2 A Macroseismic Atlas that shows the macroseismic aspect of
the most relevant events;
3 A Macroseismic Catalogue that translates in numeric terms the
Atlas.

To these is added a comprehensive Bibliography subdivided into 24
chapters each of which covers one of the 24 time periods into which the
catalogue has been subdivided.
The Analytical Catalogue besides giving the main parameters for each
earthquake (date, epicentre, hypocentral depth, MCS scale intensity, raagnitudo,
each with its own reliability index gives indications also on the
following sideline data:
1 epicentral location (meaning by this the geographic region and
the eventual indication that the epicentre is to be found on a borderline
touching more geographic regions, or in the sea, or on the coast, or othermise
in the external band (see text;
2 with a reference to the Atlas, the event is shown as having been
dealt with also mocroseismic data and it will con be found, as such, in
the Atlas and in the Macroseismic Catalogue;
3 indications on the typology of the earthquake: i.e. whether it is an
« isolated » earthquake, or a « seismic period » (and if so with the indication
of the foreshock, main or aftershocks or of a swarm;
4 the possibility of indicating up to 7 sets of information suitably
chose among 40 additional notes regarding instrumental, geophysical

DISEÑO DE UN MICROSISTEMA PROGRAMABLE PARA EFECTOS DE AUDIO DIGITAL USANDO FPGAS

Directory of Open Access Journals (Sweden)

John Michael Espinosa Durán

Full Text Available Este artículo describe el diseño de un microsistema programable para el procesamiento de efectos de audio digital implementado en un FPGA. El microsistema es diseñado usando un procesador de propósito específico y reconfigurable, un banco de RAMs y una interfaz gráfica de usuario basada en una pantalla táctil LCD. El procesador es diseñado usando 15 efectos de audio basados en retardos y procesamiento en el dominio dinámico y de la frecuencia. Los efectos son diseñados usando Megafunciones y el compilador FIR de Quartus II, son simulados en Simulink5 usando DSP Builder6, y son configurados utilizando una interfaz gráfica de usuario. El microsistema programable es implementado en el sistema de desarrollo DE2-70, y su funcionamiento es verificado usando un reproductor MP3 y un parlante. Adicionalmente, el microsistema permite la generación de efectos con alta fidelidad usando una tasa de muestreo máxima de 195.62 MSPS, y puede ser embebido en un SoC.

HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex

Directory of Open Access Journals (Sweden)

He-Ting Mao

2016-05-01

Full Text Available During virus infection, the cascade signaling pathway that leads to the production of proinflammatory cytokines is controlled at multiple levels to avoid detrimental overreaction. HACE1 has been characterized as an important tumor suppressor. Here, we identified HACE1 as an important negative regulator of virus-triggered type I IFN signaling. Overexpression of HACE1 inhibited Sendai virus- or poly (I:C-induced signaling and resulted in reduced IFNB1 production and enhanced virus replication. Knockdown of HACE1 expression exhibited the opposite effects. Ubiquitin E3 ligase activity of the dead mutant HACE1/C876A had a comparable inhibitory function as WT HACE1, suggesting that the suppressive function of HACE1 on virus-induced signaling is independent of its E3 ligase activity. Further study indicated that HACE1 acted downstream of MAVS and upstream of TBK1. Mechanistic studies showed that HACE1 exerts its inhibitory role on virus-induced signaling by disrupting the MAVS-TRAF3 complex. Therefore, we uncovered a novel function of HACE1 in innate immunity regulation.

CSN1S2 protein of goat milk inhibits the decrease of viability and increases the proliferation of MC3T3E1 pre-osteoblast cell in methyl glyoxal exposure

Directory of Open Access Journals (Sweden)

Choirunil Chotimah

2015-03-01

Full Text Available Objective: To investigate whether the CNS1S2 protein of goat milk is able to inhibit the toxicity of methyl glyoxal (MG towards MC3T3E1 pre-osteoblast cells. Methods: At confluency, pre-osteoblast cells were divided into five groups which included control (untreated, pre-osteoblast cells exposed to 5 µmol/L MG, pre-osteoblast cells exposed to MG in the presence of CSN1S2 protein at doses of 0.025, 0.050, and 0.100 mg/L, respectively. Analysis of reactive oxygen species was done with 2,7-dichlorodihydrofluorescein diacetate fluorochrome. The proliferation and viability of MC3T3E1 cells were measured by trypan blue staining. Malondialdehyde analysis was done colorimetrically. Results: Cell's viabilities were significantly lower in MG+0.050 mg/L CSN1S2 protein of goat milk compared to MG group (P<0.05. MG+0.100 mg/L CSN1S2 protein of goat milk significantly increased the cells viability compared to MG group (P<0.05. The levels of proliferation were significantly higher in MG+0.100 mg/L CSN1S2 protein of goat milk compared to control group and all treatment groups, respectively (P<0.05. Conclusions: High dose of CSN1S2 protein of goat milk (0.100 mg/L in high MG environment inhibits the decrease of viability due to the increases of the proliferation of MC3T3E1 preosteoblast cell.

Influence of CSN1S2 protein from Caprine milk Etawah Breed (EB) on histology of microglial cells in rat (Rattus norvegicus) Type-2 diabetes mellitus (T2DM)

Science.gov (United States)

Rika, Margareth; Fatchiyah

2017-11-01

Type-2 diabetes mellitus (T2DM) is a degenerative disease that causes an imbalance in the metabolism. The aim of this research is to determine the influences of CSN1S2 on the structure of microglial cells in T2DM. Rats (Rattus norvegicus) were divided into eight groups of treatment with looping three times each between treatment groups (CM) Control. The control is given a milk treatment with doses of 375 mg/kg (CM375), 750 mg/kg (CM750), and 1500 mg/kg (CM1500), T2DM (DMK), and T2DM with CSN1S2 375 mg/kg dose (DM375), 750mg/kg (DM750), and 1500 mg/kg (DM1500). The animal model T2DM was induced by a high-fat diet in the form of feed followed by injection of STZ (dose of 25 mg/kg of animal treatment) and treatment of CSN1S2 for 28 days. Brain organs were taken and analysed in histopathology stained by Hematoxylin-eosin (HE) and observed using Olympus BX53. Based on the results, it was concluded that CSN1S2 protein is influential for induction of microglial cell proliferation in animal models of T2DM, as immunity responds to the inflammatory condition in T2DM.

Instruction of the CSN on the requirements of the system of management of the nuclear power plants

International Nuclear Information System (INIS)

Cid, R.; Santo, A. de; Gil Montes, B.; Toca, A.

2008-01-01

The Western European Nations Regulatory Authorities (WENRA) performed a nuclear safety requirements harmonization task, as a result of this work and its implementation, the Spanish Nuclear Safety Counsel (CSN) has the commitment to issue its own Regulation Safety Instructions) to identify the WENRA to level nuclear safety requirements, and to incorporate it in the Spanish regulatory pyramid. However, the Spain nuclear installations meet these requirements through the original criteria to fulfill the regulation of the country that supply the NSSS design, these requirements are not incorporated in our regulation. One of the issues, identified by WENRA, is the implementation of the management system requirements in accord with the IAEA GS-R-3 The Management System for Facilities and Activities. As these regards, the CSN has developed a Safety Instruction, basically endorsing the IAEA GS-R-3. The Safety Instruction is actually in a phase of external comments and should be issued by june 2008. This paper describes the bases for the Safety Instruction, summarises the requirements that would meet the management system for nuclear installations and the activities to perform for its implementations. (Author)

CSN e Volta Redonda: uma relação histórica de dependência e controle.

Directory of Open Access Journals (Sweden)

Raphael Jonathas da Costa Lima

2013-12-01

Full Text Available http://dx.doi.org/10.5007/2175-7984.2013v12n25p41 A partir da caracterização da morfologia do espaço de Volta Redendoa (RJ, o artigo analisa a relação de dependência e controle ocasionada pela presença e atuação da Companhia Siderúrgica Nacional (CSN neste município. Entende-se que, nas últimas décadas, a Companhia disciplinou o território e restringiu as possibilidades de um desenvolvimento que não passasse pela atividade siderúrgica - até pouco tempo seu core business. O artigo parte de uma interpretação da matriz socioantropolótica do fenômeno company town e sugere que Volta Redonda ainda preserva características fundamentais deste modelo de controle e hierarquia do espalo, em geral identificadas na configuração da sua paisagem urbana. Com isso, procura compreender as implicações decorrentes do desenho monoindustrial e das mudanças técnicas e organizacionais da CSN sobre a geografia econômica do município.

Review of the Main Activities Carried out by the CSN in the Last Five Years

International Nuclear Information System (INIS)

2006-01-01

Nearing the time to finalise a new phase for the Consejo de Seguridad Nuclear, it is time to make a brief account of the main activities carried out over the past five years. During this period, one in which the CSN celebrated its 25th Anniversary, the organisation has served a social demand in a modernisation and adjustment process, followed by the continuous improvement process which throughout its history the former management, teams have carried out with great stamina and dedication. (Author)

¿Como se hace publicidad por internet?

Directory of Open Access Journals (Sweden)

Franz Del Pozo

2015-01-01

Full Text Available Internet es el medio de comunicación y venta con el mayor potencial de crecimiento y efectividad al más bajo precio. Para vender se usan tarjetas de crédito, depósitos bancarios, franqueo, comercio electrónico. Explica qué y cómo se hace publicidad por Internet. La Red se usa para difundir y para vender y hay la posibilidad de hacer algo diferente a más de llegar directamente al público objetivo se interactúa con él.

Datalogger usando nios ii

OpenAIRE

Campoverde Rugel, Luis Enrique; Velásquez Vargas, Washington Adrián; Ponguillo, Ronald

2013-01-01

El presente proyecto consiste en la implementación de un Datalogger utilizando el microprocesador NIOS II el cual fue embebido en el FPGA CYCLONE II que se encuentra integrada en la tarjeta de desarrollo ALTERA DE2, el cual obtiene datos de distintos sensores y los almacena en una tarjeta SD Card. Para la realización del proyecto se aplican cuatro etapas. La primera etapa está basada en obtener los datos mediante el uso de sensores y la transmisión usando un PIC, la siguiente etapa se basa...

Community Seismic Network (CSN)

Science.gov (United States)

Clayton, R. W.; Heaton, T. H.; Kohler, M. D.; Cheng, M.; Guy, R.; Chandy, M.; Krause, A.; Bunn, J.; Olson, M.; Faulkner, M.; Liu, A.; Strand, L.

2012-12-01

We report on developments in sensor connectivity, architecture, and data fusion algorithms executed in Cloud computing systems in the Community Seismic Network (CSN), a network of low-cost sensors housed in homes and offices by volunteers in the Pasadena, CA area. The network has over 200 sensors continuously reporting anomalies in local acceleration through the Internet to a Cloud computing service (the Google App Engine) that continually fuses sensor data to rapidly detect shaking from earthquakes. The Cloud computing system consists of data centers geographically distributed across the continent and is likely to be resilient even during earthquakes and other local disasters. The region of Southern California is partitioned in a multi-grid style into sets of telescoping cells called geocells. Data streams from sensors within a geocell are fused to detect anomalous shaking across the geocell. Temporal spatial patterns across geocells are used to detect anomalies across regions. The challenge is to detect earthquakes rapidly with an extremely low false positive rate. We report on two data fusion algorithms, one that tessellates the surface so as to fuse data from a large region around Pasadena and the other, which uses a standard tessellation of equal-sized cells. Since September 2011, the network has successfully detected earthquakes of magnitude 2.5 or higher within 40 Km of Pasadena. In addition to the standard USB device, which connects to the host's computer, we have developed a stand-alone sensor that directly connects to the internet via Ethernet or wifi. This bypasses security concerns that some companies have with the USB-connected devices, and allows for 24/7 monitoring at sites that would otherwise shut down their computers after working hours. In buildings we use the sensors to model the behavior of the structures during weak events in order to understand how they will perform during strong events. Visualization models of instrumented buildings ranging

Results of the Interlaboratory Exercise CSN/CIEMAT-100 Among Environmental Radioactivity Laboratories (Soil); Resultados del Ejercicio Interlaboratorios de Radiactividad Ambiental CSN/CIEMAT-00 (Suelo)

Energy Technology Data Exchange (ETDEWEB)

Romero Gonzalez, M. L.

2002-07-01

The document describes the outcome of the CSN/CIEMAT-00 interlaboratory test comparison among environmental radioactivity laboratories. the exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC Harmonized Protocol for the proficiency testing of analytical laboratories. the test sample was a soil containing environmental levels of K-40, Ra-226, Ac-228, Sr-90, Cs-137, Cs-134, Pu (239-240) y Am-241. the Universidad Autonoma de Barcelona prepared the material and reported adequate statistical studies of homogeneity. The results of the exercise were computed for 30 participating laboratories, and their analytical performance was assessed using the u-score approach. A raised percentage of satisfactory laboratory performance has been obtained for all the analysis, being the best performance in gamma measurements. The exercise has drawn that several laboratories have difficulties in the evaluation of combined uncertainty, mainly in analysis involving radiochemical steps. The study has shown an homogeneous inter-laboratory behaviour, and the improvement achieved through subsequent exercises in the quality of the data they are producing. (Author) 10 refs.

La unión hace la fuerza [Editorial

Directory of Open Access Journals (Sweden)

Carmen Marta-Lazo

2017-07-01

Full Text Available En el ámbito de la investigación, en general, y de la divulgación científica, en particular, el trabajo en redes es fundamental para poder potenciar proyectos conjuntos y aumentar las posibilidades de ampliar los resultados. Desde hace ya algunos años, la editora de esta revista, la Doctora Victoria Tur-Viñes, me ha brindado la oportunidad de colaborar, primero como miembro del Comité Científico, luego como Secretaria de Redacción, coordinando algunos monográficos, y ahora como coeditora. Parafraseando al escritor González Moore, “la generosidad es siempre el mejor camino”. Sin duda, el hecho de compartir tiempos y entornos hace que confluyan nuevas sinergias hacia un mismo horizonte, que la Revista Mediterránea de Comunicación/Mediterranean Journal of Communication continúe proyectándose como una fuente caudalosa de conocimiento que siga cosechando nuevos éxitos. Hablando de ellos, en el mes de mayo, recibimos la buena noticia, de que RMC ha pasado a estar indexada en EMERGING SOURCE CITATION INDEX (ESCI- Clarivate (antigua Thomson Reuters. En esta base de datos, figuran las publicaciones científicas que están siendo evaluadas para entrar a formar parte de Web of Science Core Collections Web of Science (SCI, SSCI & A&HCI. La inclusión mejora ostensiblemente la visibilidad de la revista y permitirá disponer de métricas de citación en esta base de datos.

Reconocimiento de Huellas Dactilares Usando Características Locales

Directory of Open Access Journals (Sweden)

Gualberto Aguilar

2008-01-01

Full Text Available El reconocimiento de huellas dactilares es uno de los métodos más populares usados con mayor grado de éxito para la identificación de personas. La huella dactilar tiene características únicas llamadas minucias, las cuales son puntos donde los bordes terminan o se dividen. Los sistemas de identificación que usan patrones biométricos de huella dactilar se denominan AFIS (Sistema de Identificación Automático de Huella Dactilar. En este trabajo se realizó un sistema para reconocimiento de huella dactilar usando combinación de Transformada Rápida de Fourier (FFT con Filtros de Gabor para aclarar la imagen y después un novedoso método para el reconocimiento usando características locales.

Reconocimiento de Gestos usando Cámaras de Profundidad

OpenAIRE

JHONSON GARCÍA, FIORELLA ANNETH

2017-01-01

El proyecto pretende detectar un repertorio de gestos a partir de nubes de puntos 3D obtenidas con cámaras de profundidad tipo Kinect. Jhonson García, FA. (2017). Reconocimiento de Gestos usando Cámaras de Profundidad. http://hdl.handle.net/10251/91700 TFGM

Identificación de sistemas no lineales usando series Volterra – Laguerre

OpenAIRE

Medina Ramos, Carlos Celestino; Medina Ramos, Carlos Celestino

2011-01-01

Este trabajo de Tesis está enfocado en la identificación de sistemas no lineales de modelo dinámico no conocido, adicionalmente y en base a los resultados obtenidos, se propone la aplicación del sistema de Control Predictivo no Lineal Basado en Modelos, NMPC, usando el algoritmo de la Matriz Dinámica de Control no Lineal, NDMC. El primer objetivo de este trabajo consiste en implementar una metodología para la identificación de sistemas no lineales usando series de Volterra truncadas; proye...

Selection of refractory materials for acid tanks at the CSN continuous pickling line

International Nuclear Information System (INIS)

Silva, Sidiney Nascimento; Marques, Oscar Rosa; Bueno, Mauricio Chaves; Longo, Elson; Silva Pinheiro, Adriano da

1997-01-01

Aiming at the revamping of the CSN continuous pickling line 4 acid tanks, a Post Mortem study of the refractory lining was carried out. The collected samples were characterized through techniques such as chemical analysis, mercury porosimetry, X-ray diffraction and scanning electronic microscopy. Trying to reproduce the operational conditions closely, laboratorial simulations were carried out. Such simulations lead to the addition of some alterations on the test method proposed by ABNT. Primarily, the sulfuric acid was substituted by hydrochloric acid (30%), containing iron in solution (130g/l). As result, it was concluded that acid resistant refractories containing a smaller alumina and /or corundum and mullite concentrations, presenting a smaller open porosity and average pore diameter, have a better performance face to corrosion due to hydrochloric acid solution. In addition, abrasion wear resistance tests, according to the ASTM-G65-85 standard were carried out in order to select different materials to the acid tanks cells. (author)

Results of the Interlaboratory Exercise CSN/CIEMAT-02 Among Environmental Radioactivity Laboratories (Sea Fish); Resultados del Ejercicio Interlaboratorios de Radiactividad Ambiental CSN/CIEMAT-02 (Fauna Marina)

Energy Technology Data Exchange (ETDEWEB)

Romero gonzalez, M. L.

2003-07-01

The document describes the outcome of the CSN/CIEMAT-02 interlaboratory test comparison among environmental radioactivity laboratories. The exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC Harmonized Protocol for the proficiency testing of analytical laboratories. The test sample was a reference materials provided by the IAEA-MEL (IAE Marine Environmental Laboratory, Monaco), a sea fish containing environmental levels of U-238, U-234, K-40, Pb-210, Ra-226, Sr-90, Cs-137, Co-60, Pu-(239+240), Am-241 and Tc-99. The results of the exercise were computed for 32 participating laboratories, and their analytical performance was assessed using the z-score approach. A raised percentage of satisfactory laboratory performance has been obtained for all the analysis, being the best performance in gamma measurements. The laboratories have made an effort to calculate the combined uncertainty of the radiochemical determinations. Most of the laboratories have demonstrated its competence in performing the study analysis and also the adequate measuring capability of their detection equipment even in conditions close to detection limits. The study has shown the capacity of participant laboratories to perform radioactive determinations in environmental sea fish samples with satisfactory quality levels. (Author) 6 refs.

Estimates of epistatic and pleiotropic effects of casein alpha s1 (CSN1S1) and thyroglobulin (TG) genetic markers on beef heifer performance traits enhanced by selection

Science.gov (United States)

Genetic marker effects and type of inheritance are estimated with poor precision when minor marker allele frequencies are low. A stable composite population (MARC II) was subjected to marker assisted selection for two years to equalize CSN1S1 and TG genetic marker frequencies to evaluate the epista...

Results of the Interlaboratory Exercise CSN/CIEMAT-100 Among Environmental Radioactivity Laboratories (Soil)

International Nuclear Information System (INIS)

Romero Gonzalez, M. L.

2002-01-01

The document describes the outcome of the CSN/CIEMAT-00 interlaboratory test comparison among environmental radioactivity laboratories. the exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC Harmonized Protocol for the proficiency testing of analytical laboratories. the test sample was a soil containing environmental levels of K-40, Ra-226, Ac-228, Sr-90, Cs-137, Cs-134, Pu (239-240) y Am-241. the Universidad Autonoma de Barcelona prepared the material and reported adequate statistical studies of homogeneity. The results of the exercise were computed for 30 participating laboratories, and their analytical performance was assessed using the u-score approach. A raised percentage of satisfactory laboratory performance has been obtained for all the analysis, being the best performance in gamma measurements. The exercise has drawn that several laboratories have difficulties in the evaluation of combined uncertainty, mainly in analysis involving radiochemical steps. The study has shown an homogeneous inter-laboratory behaviour, and the improvement achieved through subsequent exercises in the quality of the data they are producing. (Author) 10 refs

La teología desafiada por un Dios que se hace historia

Directory of Open Access Journals (Sweden)

Sergio Silva

2011-01-01

Full Text Available El artículo parte afirmando el carácter histórico de la teología, que le viene por el hecho de ser obra de seres humanos. Es histórico todo ser que está en devenir, lo que implica estar siendo, en relación con el entorno, desde un centro interior de conciencia y libertad, capaz de decidir. usando una analogía musical, la teología es histórica no solo porque su intérprete, el ser humano, es histórico, sino también y sobre todo porque su tema lo es: el Dios que se encarna y, así, se hace historia. De aquí los dos desafíos que aborda el artículo: a ¿Qué hace posible en Dios y en la historia humana que Dios se haga historia, es decir, que pueda devenir-en-interacción-con-los-demás-en-dirección-a-un-porvenir? La respuesta fundamental es, en Dios, que Él es Trinidad, es decir, que "deviene" con otros. Y, en la historia, el acto creador, como un poner al sujeto que puede acoger una autocomunicación de Dios fuera de sí. b ¿Cómo ha de ser la teología que piense adecuadamente este hacerse historia de Dios y cómo ha de ser el lenguaje en que se exprese esa teología? La teología debe dirigirse a los contemporáneos, porque ellos son los que experimentan el deseo de Dios puesto en ellos por el acto creador, deseo al que la teología aporta la respuesta de la revelación; debe pensar hoy al Dios testimoniado en la Escritura, el que ya se ha hecho historia; y debe buscar no tanto fijar naturalezas cuanto mostrar estructuras del devenir. El lenguaje de la teología no puede ser directo, denotativo, porque a Dios nadie lo ha visto nunca, sino indirecto, connotativo; de aquel se dan dos ejemplos: el lenguaje de Jesús en los evangelios y la propuesta de Guardini de un lenguaje indirecto, como el único capaz de asir lo viviente concreto.This article begins by affirming the historical character of theology, which comes from the fact of being the work of human beings. All beings are historic who are in the process of becoming, which

Programação funcional usando Java

OpenAIRE

Jorge Juan Zavaleta Gavidia

1997-01-01

Desde a introdução da World Wide Web para o mundo nos inícios de 1990, usando a Internet como uma rede para transferir dados, empregando uma forma de expressão chamada de Hipertexto, a qual liga as informações relacionadas e combinadas com multimídia, os Webs resultantes têm aberto novas possibilidades de expressão e comunicação. A quantidade de tráfego de dados na Web e o número de computadores ofertando informação vem crescendo dramaticamente, mas falta expressividade e qualidade interativa...

Guide of the CSN about methodology of radiological Checking of location and general levels of release; Guia del CSN sobre metodologia de comprobacion del estado radiologico de un emplazamiento y niveles genericos de liberacion

Energy Technology Data Exchange (ETDEWEB)

Sanz Alduan, M. T.

2013-07-01

The guide aims to recommend a methodology for checking radiological status of a site with a view to his release, complete and with a reasonable, statistically representative number of measures. Checking of the radiological situation of a site allows to determine if it is contaminated and, if so, whether, after cleaning performances, has reached a level of residual contamination, allowing their release with or without restrictions. Generic levels for the release without restrictions on the grounds of sites recommended for this verification of nuclear installations on the basis of the radiological dose criteria laid down in the instruction of the CSN IS-13. I agree with the IS-13, the site includes terrain, structures and facilities described in the authorization of exploitation, as well as any area has been released prior to the closing statement. The Guide recommends only the levels of release of land, regardless of the structures and facilities. (Author)

Monitorização de transplante cardíaco usando análises do eletrograma intracavitário

Directory of Open Access Journals (Sweden)

BROFMAN Paulo Roberto S.

1997-01-01

Full Text Available Uma série de registros do eletrograma intracavitário tem sido utilizada para monitorização não invasiva da rejeição em pacientes transplantados usando um marcapasso de dupla câmara e eletrodos endocavitários revestidos com estrutura fractal. Os sinais têm sido avaliados usando o sistema CHARM (Computerized Heart Acute Rejection Monitoring _ sistema computadorizado para monitorização da rejeição cardíaca aguda. Os relatórios obtidos com este sistema contêm curvas com parâmetros sensíveis à rejeição, que demonstram uma boa correlação com a clínica e os resultados das biópsias convencionais. A monitorização a longo prazo, usando estas análises, mostrou ser uma ferramenta valiosa no acompanhamento destes pacientes.

Performance en plataformas de microservicios

OpenAIRE

Kirilov Yankov, Dimitar

2017-01-01

En esta memoria se hace una introducción al ámbito de los microservicios y las tecnologías que los acompañan, describiendo de forma detallada el proceso de creación e integración de una plataforma de alto rendimiento basada en microservicios. Una vez generada la plataforma, se hace un estudio y análisis de su rendimiento en una maquina local cuando hay un gran volumen de peticiones, usando una variedad de pruebas o benchmarks y viendo en que nivel afectan al rendimiento. ...

Implementación del sistema para municipios, usando pmi

OpenAIRE

Cruz Ruiz, Victor Hugo; Buenaño Vera, Sulay Pamela; Freire Cobo, Lenin

2014-01-01

El objetivo de informe de graduación, es plantear y describir la implementación de un sistema informático en una entidad municipal usando PMI, siguiendo las pautas definidas en la Guía del PMBOK. Nuestro estudio es aplicar la Metodología Administración de Proyectos PMI a un proyecto ya terminado. Para este proyecto hemos tomado la información de la implementación del Sistema CABILDO ERP en el Gobierno Municipal de San Jacinto de Yaguachi, realizado por la empresa ecuatoriana...

Calibration of individual dosemeters by using external beams of photon radiation. A nationwide survey among Personal Dosimetry Services, authorized by CSN

International Nuclear Information System (INIS)

Brosed, A.; Ginjaume, M.

1995-12-01

A nationwide survey in 1995 among Personal Dosimetry Services, authorized by the Spanish Nuclear Safety Council (CSN), has led the Spanish Dosimetry Laboratories to review and update the dosimetric conversion coefficients and correction factors in use in Spain since 1987. The recommendations of the ICRU Report 47(1992) are discussed and adopted. In addition differences in back-scattering form IRCU tissue and PMMA phantoms are analysed. Analytical functions used to calculate conversion coefficients and back-scattering correction factors due to the use of different phantom materials are presented, together with the adopted final values. Firstly, the above mentioned parameters are applied to ISO narrow spectra series, which are discribed in this report. Secondly, differences between 1995 and 1987 values are also shown. (Author)

Results of the Interlaboratory Exercise CSN/CIEMAT-02 Among Environmental Radioactivity Laboratories (Sea Fish)

International Nuclear Information System (INIS)

Romero Gonzalez, M.L.

2003-01-01

The document describes the outcome of the CSN/CIEMAT-02 interlaboratory test comparison among environmental radioactivity laboratories. The exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC Harmonized Protocol for the proficiency testing of analytical laboratories. The test sample was a reference materials provided by the IAEA-MEL (IAE Marine Environmental Laboratory, Monaco), a sea fish containing environmental levels of U-238, U-234, K-40, Pb-210, Ra-226, Sr-90, Cs-137, Co-60, Pu-(239+240), Am-241 and Tc-99. The results of the exercise were computed for 32 participating laboratories, and their analytical performance was assessed using the z-score approach. A raised percentage of satisfactory laboratory performance has been obtained for all the analysis, being the best performance in gamma measurements. The laboratories have made an effort to calculate the combined uncertainty of the radiochemical determinations. Most of the laboratories have demonstrated its competence in performing the study analysis and also the adequate measuring capability of their detection equipment even in conditions close to detection limits. The study has shown the capacity of participant laboratories to perform radioactive determinations in environmental sea fish samples with satisfactory quality levels. (Author) 6 refs

Interação Humano - Computador usando Visão Computacional

Directory of Open Access Journals (Sweden)

Bernardo Bucher B. Barbosa

2015-07-01

Full Text Available Este trabalho visa estudar maneiras de se explorar a Interação Humano Computador, usando Visão Computacional. A idéia tem como objetivo um esforço para tornar o computador mais interativo com o usuário, sem a necessidade da compra de um hardware ou acessório específico para tal. O produto final deste trabalho em desenvolvimento é um software que contempla esta funcionalidade, tornando o computador mais interativo.

CLARIFICACIÓN DE AGUAS USANDO COAGULANTES POLIMERIZADOS: CASO DEL HIDROXICLORURO DE ALUMINIO

Directory of Open Access Journals (Sweden)

JUAN MIGUEL COGOLLO FLÓREZ

2011-01-01

Full Text Available En este artículo se realiza un estudio del proceso de clarificación en sistemas de tratamiento de aguas industriales usando un coagulante inorgánico polimerizado (hidroxicloruro de aluminio. Inicialmente, se establecen los elementos conceptuales más importantes de las etapas del proceso de clarificación (coagulación, floculación y sedimentación. Luego, se señalan los principales coagulantes convencionales utilizados en el tratamiento de aguas y se abordan los policloruros de aluminio (PAC´s como integrantes de una nueva generación de coagulantes alternativos cuyo uso se ha incrementado en las últimas décadas dado su mejor desempeño respecto a los coagulantes convencionales; se especifican los aspectos técnicos y operativos que se deben considerar al momento de implementar un proceso de clarificación de aguas usando un PAC como coagulante. Finalmente, se presentan datos comparativos de condiciones operacionales reales de un proceso de clarificación de aguas, producto de un trabajo previo, donde se remplazó un coagulante convencional (sulfato de aluminio por hidroxicloruro de aluminio, donde se corrobora el mejor desempeño del proceso luego del remplazo.

Ministros de culto y abuso sexual. ¿Existen cifras en México?: un acercamiento estadístico

Directory of Open Access Journals (Sweden)

Jorge Erdely Graham

2003-01-01

Full Text Available Se presenta una panorámica global que abarca distintas regiones, posteriormente se hace referencia al caso de México. Usando un metaanálisis, estudios de campo, datos empíricos y estadísticas, se presenta una aproximación cuantitativa preliminar y datos cualitativos sobre los casos de abuso sexual por parte de los ministros de culto de diferentes afiliaciones.

¿el proceso de enfermería hace parte de la calidad del cuidado?

OpenAIRE

ABAUNZA DE GONZÁLEZ, MYRIAM

2010-01-01

El principal propósito de este artículo es dar respuesta al siguiente interrogante: ¿El proceso de enfermería hace parte de la calidad del cuidado? Para sustentar la respuesta a la pregunta, se parte de referenciar varios autores que han hecho estudios sobre la utilización del método científico, del método de solución de problemas y del proceso de atención de enfermería y su relación con la calidad del servicio y del cuidado de enfermería, al mismo tiempo que se introducen experiencias relaci...

La lectura en el aula. Qué se hace, qué se debe hacer y qué se puede hacer

OpenAIRE

Pablo Lorente Muñoz

2011-01-01

Emilio Sánchez Miguel (Coord.). La lectura en el aula. Qué se hace, qué se debe hacer y qué se puede hacer. Graó, col. Crítica y Fundamentos, 27. Barcelona, 2010. 382 págs. ISBN: 978-84-7827-892-3

Análisis de la biodiversidad genética del algodón peruano usando marcadores moleculares: Avances en el 2004

OpenAIRE

Olórtegui, José; Espinoza, Marco; Espinoza, José; Montoya, Ysabel

2005-01-01

Tres mini preparaciones de extracción de ADN de algodón fueron comparadas en términos de calidad y rendimiento. El método de extracción de ADN usando CTAB fue el más eficiente (30 ug) en comparación con un kit comercial de extracción (20 ug) a partir de 100 mg de hojas cotiledonarias. La óptima calidad del ADN fue evaluada con las enzimas de restricción EcoRI y MseI. El ADN preparado será usado para iniciar el análisis de la biodiversidad genética del algodón peruano, usando marcadores mole...

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2011 among Spanish National Laboratories of Environmental Radioactivity (Water)

International Nuclear Information System (INIS)

Gascó, C.; Trinidad, J. A.; Llauradó, M.

2015-01-01

This report describes the results assessment of the intercomparsion exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UAB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2011) was deionized water, simulating drinking water, that was enriched with artificial radionuclides (Cs-137, Co-60, Fe-55, Ni-63, Sr-90, Am-241 and Pu-238) and contained natural radionuclides (U-234, U-238, U-natural, Pb-210, Po-210, Th-230, Ra-226 and K-40) at environmental level of activity concentration. A second matrix of deionized water was prepared with I-129 and C-14. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The study has showed a homogeneous behaviour of the laboratories.

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2012 among Spanish National Laboratories of Environmental Radioactivity (Soil); Evaluación de la Intercomparación CSN/CIEMAT-2012 entre los Laboratorios Nacionales de Radiactividad Ambiental (Suelo)

Energy Technology Data Exchange (ETDEWEB)

Trinidad, J. A.; Gascó, C.; Llauradó, M.

2015-07-01

This report describes the results assessment of the intercomparsion exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2012) was soil, that was enriched with artificial radionuclides (137Cs, 60Co, 55Fe, 63Ni, 90Sr, 241Am, 239+240Pu and 238Pu) and contained natural radionuclides (234U, 238U, U-natural 230Th, 226Ra, 210Pb, 228Ra, 228Ac, 234Th, 214Bi, 214Pb, 212Pb, 208Tl and 40K) at environmental level of activity concentration. Two soil matrixes were prepared in order to separate 55Fe and 63Ni analysis. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The study has showed a homogeneous behaviour of the laboratories.

Measurement of nuclear cross sections using radioactive beams; Medicion de secciones eficaces nucleares usando haces radiactivos

Energy Technology Data Exchange (ETDEWEB)

Lizcano, D.; Aguilera, E.F.; Martinez Q, E. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

2000-07-01

One of the main applications of the production and use of nuclear radioactive beams is the measurement of nuclear cross sections. In this work is used a {sup 6} He nuclear radioactive beam ({beta} emitting with half life 806.7 ms) for the study of the reaction {sup 6} + {sup 209} Bi which could have several products. This investigation was realized in collaboration with the personnel of the Nuclear Structure laboratory at the University of Notre Dame (U.S.A.) and the National institute of Nuclear Research and CONACyT by Mexico. (Author)

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2013 among Spanish National Laboratories of Environmental Radioactivity (Air)

International Nuclear Information System (INIS)

Trinidad, J. A.; Gascó, C.; Llauradó, M.

2015-01-01

This report describes the results assessment of the intercomparsion exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2013) was filters, which was enriched with artificial radionuclides (137Cs, 60Co and 57Co) and contained natural radionuclides (234U, 238U, U-natural 230Th, 226Ra, 210Pb, 234Th, 214Bi and 214Pb) at environmental level of activity concentration. Three commonly used filters (47 mm diameter, 44x44 cm2 and 20x25 cm2) were prepared. Two 47 mm diameter filter were prepared to separate 226Ra and 210Pb analysis. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The study has showed a homogeneous behaviour of the laboratories

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2012 among Spanish National Laboratories of Environmental Radioactivity (Soil)

International Nuclear Information System (INIS)

Trinidad, J. A.; Gascó, C.; Llauradó, M.

2015-01-01

This report describes the results assessment of the intercomparsion exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2012) was soil, that was enriched with artificial radionuclides (137Cs, 60Co, 55Fe, 63Ni, 90Sr, 241Am, 239+240Pu and 238Pu) and contained natural radionuclides (234U, 238U, U-natural 230Th, 226Ra, 210Pb, 228Ra, 228Ac, 234Th, 214Bi, 214Pb, 212Pb, 208Tl and 40K) at environmental level of activity concentration. Two soil matrixes were prepared in order to separate 55Fe and 63Ni analysis. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The study has showed a homogeneous behaviour of the laboratories.

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2010 among Spanish National Laboratories of Environmental Radioactivity (Diet Ashes); Evaluacion de la Intercomparacion CSN/CIEMAT-2010 entre los Laboratorios Nacionales de Radiactividad Ambiental (Ceniza de Dieta)

Energy Technology Data Exchange (ETDEWEB)

Gasco, C.; Trinidad, J. A.; Llaurado, M.; Suarez, J. A.

2012-06-08

This report describes the results assessment of the intercomparison exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UAB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2010) was a diet ash obtained from the ashing of a whole fresh diet (breakfast, lunch and dinner), that was enriched with artificial radionuclides (Cs-137, Co-60,Fe-55,Ni-63,Sr-90,Am-241,Pu-238,Pu-239,240 y C-14) and contained natural radionuclides (U-234, U-238, U-natural Th-230, Th-234, Ra-226, Ra-228, Pb-210, Pb-212, Pb-214, Bi-214, Ac-228, Tl-208, K-40) at environmental level of activity concentration. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The reference values obtained through the medians show a negative bias for Pb-210 and Th-234 when comparing to the given values of external qualified laboratories from ENEA and IRSN and positive one for K-40. (Author)

Hoy hace: la erupción del Rincón de la Vieja el 8 de mayo de 1991

Directory of Open Access Journals (Sweden)

Soto Bonilla, Gerardo

2005-08-01

Full Text Available Uno de los eventos volcánicos importantes del siglo XX en Costa Rica fue el ocurrido el 8 de mayo del año 1991 en el Volcán Rincón de la Vieja. A continuación, se muestra la información recopilada en la serie Hoy hace. concerniente a la emergencia suscitada en esa ocasión. Se incluye una relación de las principales observaciones reportadas con respecto al Volcán desde el año 1765 hasta el año 1998. El documento explica el mecanismo de la erupción principal y enlista las actividades posteriores que se dieron One of the important volcanic events of the 20th Century in Costa Rica was the one of May 8, 1991 at the Rincón de la Vieja Volcano. Following, it shows the information collected in the series Today in History (Hoy hace related to the emergency generated at that moment. It includes a relation to the main observations reported in regards to the Volcano from the year 1765 to the year 1998. The document explains the mechanism of the main eruption and lists the posterior activities

Hydraulic Analysis of the Contribution of Emergency Water to C. N. Almaraz Systems Affected as a Result of the Complementary Technical Instructions issued by the CSN after Fukushima

International Nuclear Information System (INIS)

Vilar Carmona, G.; Puertas Munoz, S.; Arguello Tara, A.; Sanz Roman, F. J.

2013-01-01

This paper presents the study and hydraulic analysis of the capacity required contribution of emergency water to the Almaraz NPP to power systems deal with the accidental events outside the bases of design defined in the Complementary technical instructions generated by the CSN after Fukushima. Through the program of balanced hydraulic SBAL, developed by entrepreneurs Grouped (EE.AA) and used in multiple security systems analysis, and based on designs and requirements to be fulfilled by the Almaraz NPP of the different strategies are set, have developed a series of hydraulic models that they have allowed the definition and dimensioning of the portable media and the new connections required in the central systems.

CUANDO LA ENSEÑANZA HACE SUJETO, EL CONCEPTO DE IDENTIDAD CUESTIONADO

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Adrián Villalba

2017-02-01

Full Text Available El advenimiento del psicoanálisis hace ya más de cien años trajo consigo nuevas perspectivas sobre el pensamiento acerca del hombre. Poniendo en duda las certezas que el pensamiento cartesiano había instituido, procura cierta  influencia sobre diferentes campos que versan sobre lo humano. En este sentido, el presente trabajo aborda las consideraciones que el concepto de identificación, tal como es entendido por Freud primero y Lacan después, establece ineluctablemente en un pretendido sujeto pasible de enseñanza. Palabras clave: identificación, identidad, psicoanálisis, enseñanza. WHEN TEACHING MAKES A SUBJECT: THE CONCEPT OF IDENTITY BEING QUESTIONED Abstract The advent of psychoanalysis, over one hundred years ago, brought about new perspectives on thoughts about humankind. It calls into question the certainties that Cartesian thinking had instituted and it tries to influence different fields of study that deal with what it is to be human. In this sense, this work addresses aspects that the concept of identification, as it is understood first by Freud and then by Lacan, ineluctably establishes in a purported subject who could be a subject of teaching. Key words: identification, identity, psychoanalysis, teaching.

Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes

Energy Technology Data Exchange (ETDEWEB)

Rockel, Beate [Department of Molecular Structural Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried (Germany); Schmaler, Tilo; Huang, Xiaohua [Division of Molecular Biology, Department of General, Visceral, Vascular and Thoracic Surgery, Charité – Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin (Germany); Dubiel, Wolfgang, E-mail: Wolfgang.dubiel@charite.de [Division of Molecular Biology, Department of General, Visceral, Vascular and Thoracic Surgery, Charité – Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin (Germany)

2014-07-25

Highlights: • Deneddylation rates of human erythrocyte and mouse fibroblast CSN are very similar. • 3D models of native human and mouse CSN reveal common architectures. • The cryo-structure of native mammalian CSN shows a horseshoe subunit arrangement. - Abstract: The COP9 signalosome (CSN) is a regulator of the ubiquitin (Ub) proteasome system (UPS). In the UPS, proteins are Ub-labeled for degradation by Ub ligases conferring substrate specificity. The CSN controls a large family of Ub ligases called cullin-RING ligases (CRLs), which ubiquitinate cell cycle regulators, transcription factors and DNA damage response proteins. The CSN possesses structural similarities with the 26S proteasome Lid complex and the translation initiation complex 3 (eIF3) indicating similar ancestry and function. Initial structures were obtained 14 years ago by 2D electron microscopy (EM). Recently, first 3D molecular models of the CSN were created on the basis of negative-stain EM and single-particle analysis, mostly with recombinant complexes. Here, we compare deneddylating activity and structural features of CSN complexes purified in an elaborate procedure from human erythrocytes and efficiently pulled down from mouse Flag-CSN2 B8 fibroblasts. In an in vitro deneddylation assay both the human and the mouse CSN complexes deneddylated Nedd8-Cul1 with comparable rates. 3D structural models of the erythrocyte CSN as well as of the mouse Flag-CSN were generated by negative stain EM and by cryo-EM. Both complexes show a central U-shaped segment from which several arms emanate. This structure, called the horseshoe, is formed by the PCI domain subunits. CSN5 and CSN6 point away from the horseshoe. Compared to 3D models of negatively stained CSN complexes, densities assigned to CSN2 and CSN4 are better defined in the cryo-map. Because biochemical and structural results obtained with CSN complexes isolated from human erythrocytes and purified by Flag-CSN pulldown from mouse B8 fibroblasts

Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes

International Nuclear Information System (INIS)

Rockel, Beate; Schmaler, Tilo; Huang, Xiaohua; Dubiel, Wolfgang

2014-01-01

Highlights: • Deneddylation rates of human erythrocyte and mouse fibroblast CSN are very similar. • 3D models of native human and mouse CSN reveal common architectures. • The cryo-structure of native mammalian CSN shows a horseshoe subunit arrangement. - Abstract: The COP9 signalosome (CSN) is a regulator of the ubiquitin (Ub) proteasome system (UPS). In the UPS, proteins are Ub-labeled for degradation by Ub ligases conferring substrate specificity. The CSN controls a large family of Ub ligases called cullin-RING ligases (CRLs), which ubiquitinate cell cycle regulators, transcription factors and DNA damage response proteins. The CSN possesses structural similarities with the 26S proteasome Lid complex and the translation initiation complex 3 (eIF3) indicating similar ancestry and function. Initial structures were obtained 14 years ago by 2D electron microscopy (EM). Recently, first 3D molecular models of the CSN were created on the basis of negative-stain EM and single-particle analysis, mostly with recombinant complexes. Here, we compare deneddylating activity and structural features of CSN complexes purified in an elaborate procedure from human erythrocytes and efficiently pulled down from mouse Flag-CSN2 B8 fibroblasts. In an in vitro deneddylation assay both the human and the mouse CSN complexes deneddylated Nedd8-Cul1 with comparable rates. 3D structural models of the erythrocyte CSN as well as of the mouse Flag-CSN were generated by negative stain EM and by cryo-EM. Both complexes show a central U-shaped segment from which several arms emanate. This structure, called the horseshoe, is formed by the PCI domain subunits. CSN5 and CSN6 point away from the horseshoe. Compared to 3D models of negatively stained CSN complexes, densities assigned to CSN2 and CSN4 are better defined in the cryo-map. Because biochemical and structural results obtained with CSN complexes isolated from human erythrocytes and purified by Flag-CSN pulldown from mouse B8 fibroblasts

Construcción de Distribuciones Multivariadas con Marginales Dependientes Usando Cópulas en R

OpenAIRE

Jaramillo-Elorza, M. C; Lozano, J. A

2014-01-01

Las cópulas se han convertido en una herramienta popular para la construcción de modelos multivariados en campos donde la dependencia multivariada es de gran interés. El propósito de este trabajo es presentar las cópulas tanto en su concepto teórico, como en su implementación en el software estadístico R y profundizar en la construcción de distribuciones multivariadas con marginales dependientes, usando la clase mvdc del paquete copula, la cual permite utilizar varias y diferentes marginales ...

The COP9 Signalosome regulates seed germination by facilitating protein degradation of RGL2 and ABI5.

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Dan Jin

2018-02-01

Full Text Available The control of seed germination and seed dormancy are critical for the successful propagation of plant species, and are important agricultural traits. Seed germination is tightly controlled by the balance of gibberellin (GA and abscisic acid (ABA, and is influenced by environmental factors. The COP9 Signalosome (CSN is a conserved multi-subunit protein complex that is best known as a regulator of the Cullin-RING family of ubiquitin E3 ligases (CRLs. Multiple viable mutants of the CSN showed poor germination, except for csn5b-1. Detailed analyses showed that csn1-10 has a stronger seed dormancy, while csn5a-1 mutants exhibit retarded seed germination in addition to hyperdormancy. Both csn5a-1 and csn1-10 plants show defects in the timely removal of the germination inhibitors: RGL2, a repressor of GA signaling, and ABI5, an effector of ABA responses. We provide genetic evidence to demonstrate that the germination phenotype of csn1-10 is caused by over-accumulation of RGL2, a substrate of the SCF (CRL1 ubiquitin E3 ligase, while the csn5a-1 phenotype is caused by over-accumulation of RGL2 as well as ABI5. The genetic data are consistent with the hypothesis that CSN5A regulates ABI5 by a mechanism that may not involve CSN1. Transcriptome analyses suggest that CSN1 has a more prominent role than CSN5A during seed maturation, but CSN5A plays a more important role than CSN1 during seed germination, further supporting the functional distinction of these two CSN genes. Our study delineates the molecular targets of the CSN complex in seed germination, and reveals that CSN5 has additional functions in regulating ABI5, thus the ABA signaling pathway.

Valoración de la formación recibida usando un perfil de referencia basado en competencias profesionales

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Mónica Maldonado Rojas

Full Text Available Introducción: La formación profesional está hoy en día promoviendo la implementación de opciones educativas basadas en modelos por competencias. El presente trabajo tuvo como propósito establecer un perfil de referencia basado en competencias profesionales para la carrera de Tecnología Médica de la Universidad de Talca y usando éstas como indicadores, conocer la auto percepción que tienen los egresados respecto del grado en que fueron adquiridas durante su formación. Material y métodos: Se realizó una investigación de tipo exploratoria, mediante una encuesta autoaplicada que contenía un conjunto de indicadores que correspondían a competencias establecidas previamente en un perfil de referencia, cuya estructura considera diferentes áreas de desempeño. El perfil fue validado por juicio de expertos, determinando el grado de congruencia a través del coeficiente de Serafine. La construcción de la información se realizó a partir de las repuestas, las que fueron codificadas y representadas en porcentajes y posteriormente analizadas bajo categorías interpretativas. Resultados: La evaluación que se hace considera el porcentaje de egresados que valoró el logro de las competencias por área de desempeño en los niveles más altos. Los resultados obtenidos fueron: Para el área asistencial el 72,9 %, para el área investigación un 59 %, para el área de docencia un 44%, para el área administrativa un 27,1% y para el área personal-social un 91,3 %. Conclusiones: Siguiendo el criterio de categorías interpretativas, el área personal social indica una gran fortaleza de la formación, el área asistencial y el área investigación se encuentran en un nivel satisfactorio y las áreas docencia y administración en niveles medianamente satisfactorio, siendo esta última la gran falencia de la formación. El currículo vigente es adecuado para asegurar el logro de gran número de competencias, pero se debe revisar con el objetivo de

DESARROLLO DE UN SISTEMA DE NEURO-MERCADOTECNIA USANDO EL DISPOSITIVO EMOTIV-EPOC

OpenAIRE

Luz Ángela Moreno; César Augusto Peña; Oscar Eduardo Gualdron

2014-01-01

Este artículo presenta los avances concebidos en la realización de un sistema de neuro-mercadotecnia. El objetivo del sistema es permitir evaluar las emociones que presentan los televidentes al observar comerciales publicitarios. Se hace uso de la interfaz cerebro-computador Emotiv-EPOC para la adquisición de las neuro-señales. Se describen los algoritmos empleados para el análisis de las pautas publicitarias. Se presentan unas pruebas experimentales donde se comparan los resultados obtenidos...

Guía metodológica para obtener patrones de accidentabilidad laboral usando Data Mining

OpenAIRE

Cevallos Chacón, Alvaro

2013-01-01

El objetivo de esta investigación es desarrollar y proponer una metodología clara y objetiva que permita a las empresas de cualquier industria, investigar sobre patrones de accidentabilidad laboral usando la minería de datos como herramienta de análisis. Para tal efecto se combina los conceptos de seguridad industrial relacionados con la investigación de accidentes y toma como marco principal, la normatividad nacional vigente en materia de seguridad y salud en el trabajo. Estos conceptos son ...

Casein haplotypes and their association with milk production traits in Norwegian Red cattle

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Nome Torfinn

2009-02-01

Full Text Available Abstract A high resolution SNP map was constructed for the bovine casein region to identify haplotype structures and study associations with milk traits in Norwegian Red cattle. Our analyses suggest separation of the casein cluster into two haplotype blocks, one consisting of the CSN1S1, CSN2 and CSN1S2 genes and another one consisting of the CSN3 gene. Highly significant associations with both protein and milk yield were found for both single SNPs and haplotypes within the CSN1S1-CSN2-CSN1S2 haplotype block. In contrast, no significant association was found for single SNPs or haplotypes within the CSN3 block. Our results point towards CSN2 and CSN1S2 as the most likely loci harbouring the underlying causative DNA variation. In our study, the most significant results were found for the SNP CSN2_67 with the C allele consistently associated with both higher protein and milk yields. CSN2_67 calls a C to an A substitution at codon 67 in β-casein gene resulting in histidine replacing proline in the amino acid sequence. This polymorphism determines the protein variants A1/B (CSN2_67 A allele versus A2/A3 (CSN2_67 C allele. Other studies have suggested that a high consumption of A1/B milk may affect human health by increasing the risk of diabetes and heart diseases. Altogether these results argue for an increase in the frequency of the CSN2_67 C allele or haplotypes containing this allele in the Norwegian Red cattle population by selective breeding.

The COP9 signalosome interacts with SCF UFO and participates in Arabidopsis flower development.

Science.gov (United States)

Wang, Xiping; Feng, Suhua; Nakayama, Naomi; Crosby, W L; Irish, Vivian; Deng, Xing Wang; Wei, Ning

2003-05-01

The COP9 signalosome (CSN) is involved in multiple developmental processes. It interacts with SCF ubiquitin ligases and deconjugates Nedd8/Rub1 from cullins (deneddylation). CSN is highly expressed in Arabidopsis floral tissues. To investigate the role of CSN in flower development, we examined the expression pattern of CSN in developing flowers. We report here that two csn1 partially deficient Arabidopsis strains exhibit aberrant development of floral organs, decline of APETALA3 (AP3) expression, and low fertility in addition to defects in shoot and inflorescence meristems. We show that UNUSUAL FLORAL ORGANS (UFO) forms a SCF(UFO) complex, which is associated with CSN in vivo. Genetic interaction analysis indicates that CSN is necessary for the gain-of-function activity of the F-box protein UFO in AP3 activation and in floral organ transformation. Compared with the previously reported csn5 antisense and csn1 null mutants, partial deficiency of CSN1 causes a reduction in the level of CUL1 in the mutant flowers without an obvious defect in CUL1 deneddylation. We conclude that CSN is an essential regulator of Arabidopsis flower development and suggest that CSN regulates Arabidopsis flower development in part by modulating SCF(UFO)-mediated AP3 activation.

Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function.

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Zhipeng Zhou

Full Text Available The COP9 signalosome (CSN is a highly conserved multifunctional complex that has two major biochemical roles: cleaving NEDD8 from cullin proteins and maintaining the stability of CRL components. We used mutation analysis to confirm that the JAMM domain of the CSN-5 subunit is responsible for NEDD8 cleavage from cullin proteins in Neurospora crassa. Point mutations of key residues in the metal-binding motif (EX(nHXHX(10D of the CSN-5 JAMM domain disrupted CSN deneddylation activity without interfering with assembly of the CSN complex or interactions between CSN and cullin proteins. Surprisingly, CSN-5 with a mutated JAMM domain partially rescued the phenotypic defects observed in a csn-5 mutant. We found that, even without its deneddylation activity, the CSN can partially maintain the stability of the SCF(FWD-1 complex and partially restore the degradation of the circadian clock protein FREQUENCY (FRQ in vivo. Furthermore, we showed that CSN containing mutant CSN-5 efficiently prevents degradation of the substrate receptors of CRLs. Finally, we found that deletion of the CAND1 ortholog in N. crassa had little effect on the conidiation circadian rhythm. Our results suggest that CSN integrity plays major roles in hyphal growth, conidial development, and circadian function in N. crassa.

SISTEMA DE MODELAGEM DE FIGURAS TRIDIMENSIONAIS USANDO RECONHECIMENTO DE VOZ

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Kauan Cristiano De Souza

2017-01-01

Full Text Available Atualmente o mercado de Sistemas de Desenho auxiliado por Computador (CAD, sofre extrema carência de processos automatizados de reconhecimento de fala. O surgimento de tecnologias de automação facilita no desenvolvimento de aplicações capazes de auxiliar nestes processos. Baseando-se nestas afirmações construiu-se um modelo utilizando tecnologias capazes de transformar fala em sinais digitais, sendo possível a interpretação por sofisticados computadores. Observando ausência de tais ferramentas, o presente trabalho busca uma proposta capaz de acrescentar mecanismos os quais possibilitem a criação de modelos tridimensionais usando tecnologias como servidores HTTP, dispositivos moveis, linguagens de programação Java e PHP, Computação Gráfica e linguagem de interpretação por blocos. Os resultados obtidos na confecção do presente trabalho corroboram com as necessidades atuais representadas na sociedade propondo sustentabilidade, acessibilidade, portabilidade e facilidade de comunicação.

DESARROLLO DE UN SISTEMA DE NEURO-MERCADOTECNIA USANDO EL DISPOSITIVO EMOTIV-EPOC

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Luz Ángela Moreno

2014-11-01

Full Text Available Este artículo presenta los avances concebidos en la realización de un sistema de neuro-mercadotecnia. El objetivo del sistema es permitir evaluar las emociones que presentan los televidentes al observar comerciales publicitarios. Se hace uso de la interfaz cerebro-computador Emotiv-EPOC para la adquisición de las neuro-señales. Se describen los algoritmos empleados para el análisis de las pautas publicitarias. Se presentan unas pruebas experimentales donde se comparan los resultados obtenidos por métodos tradicionales con las propuestas.

Results Assessment of Intercomparison Exercise CSN/CIEMAT-2010 among Spanish National Laboratories of Environmental Radioactivity (Diet Ashes)

International Nuclear Information System (INIS)

Gasco, C.; Trinidad, J. A.; Llaurado, M.; Suarez, J. A.

2012-01-01

This report describes the results assessment of the intercomparison exercise among environmental radioactivity laboratories, organised by Spanish Regulatory Institution (CSN) and prepared and evaluated by UAB and CIEMAT respectively. The exercise has been carried out following the international standards ISO-43 and ISO/IUPAC that provide a useful guide to perform proficiency tests and inter-laboratories comparisons. The selected matrix for this year (2010) was a diet ash obtained from the ashing of a whole fresh diet (breakfast, lunch and dinner), that was enriched with artificial radionuclides (Cs-137, Co-60,Fe-55,Ni-63,Sr-90,Am-241,Pu-238,Pu-239,240 y C-14) and contained natural radionuclides (U-234, U-238, U-natural Th-230, Th-234, Ra-226, Ra-228, Pb-210, Pb-212, Pb-214, Bi-214, Ac-228, Tl-208, K-40) at environmental level of activity concentration. The z-score test was applied to determine how much the laboratories differ from the reference value. The reference value for this exercise was the median of the results from the different laboratories and their standard deviations to achieve a more complete and objective study of the laboratories performance. The participant laboratories have demonstrated a satisfactory quality level for measuring the natural and artificial radionuclides content in this matrix. The reference values obtained through the medians show a negative bias for Pb-210 and Th-234 when comparing to the given values of external qualified laboratories from ENEA and IRSN and positive one for K-40. (Author)

Síntesis de oxitocina en fase sólida usando derivados de terbutoxicarbonilo y fluorenilmetoxicarbonilo

OpenAIRE

Calvo, Julio C; Barrera, Nubia F.; García, Josué A.; Guzman, Fanny; Espejo, Fabiola; Patarroyo, Manuel E.

2010-01-01

La oxitocina, péptido cíclico cuya secuencia es CYIQNCPLG, fué el primer péptido de importancia biológica que pudo ser sintetizado. En este trabajo se compara la síntesis de la oxitocina usando resina p metilbenzhidrilamina (MBHA) para la síntesis por estrategia t-Boc y resina Rink p-metilbenzhidrilamina (Rink MBHA) para la síntesis por estrategia Fmoc, con altos rendimientos. El péptido crudo se ciclizó en una disolución acuosa de dimetilsulfóxido al 10%. La caracterización se llevó a cabo p...

Clinical staff nurse leadership: Identifying gaps in competency development.

Science.gov (United States)

Franks-Meeks, Sherron

2018-01-01

To date, there has been no development of a complete, applicable inventory of clinical staff nurse (CSN) leadership role competencies through a valid and reliable methodology. Further, the CSN has not been invited to engage in the identification, definition, or development of their own leadership competencies. Compare existing leadership competencies to identify and highlight gaps in clinical staff nurse leadership role competency development and validation. Literature review. The CSN has not participated in the development of CSN leadership role competencies, nor have the currently identified CSN leadership role competencies been scientifically validated through research. Finally, CSN leadership role competencies are incomplete and do not reflect the CSN perspective. © 2017 Wiley Periodicals, Inc.

Sistema Distribuido de Detección de Sismos Usando una Red de Sensores Inalámbrica para Alerta Temprana.

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Ana Zambrano Vizuete

2015-07-01

Full Text Available Resumen: El detectar eventos disruptivos usando sensores COTS como los utilizados en smartphones representa un gran desafío pero también una oportunidad interesante. En este artículo se presenta una arquitectura de sistema de tiempo real crítico, jerárquica y distribuida, que hace uso de smartphones que actúan como sensores a través de una aplicación de bajo consumo de energía que convierte a sus acelerómetros en acelerógrafos. Los smartphones desplegados forman una red de sensores que detecta, analiza y notifica un pico sísmico. El sistema optimiza cálculos distribuidos y capacidades de comunicación en smartphones para proveer tiempo extra para alertas tempranas en escenarios de desastre de tipo sísmico, aunque puede ser empleada como solución a otros desastres naturales. Se propone una solución innovadora de bajo coste que realiza análisis tanto espaciales como temporales, no presentes en otros trabajos, lo cual lo hace más preciso y personalizable permitiendo adaptarse a las características geográficas de la zona, de red, y recursos tanto humanos como monetarios. La arquitectura ha sido validada mediante una extensa evaluación, consiguiendo como resultado notificaciones tempranas que adelantan en decenas de segundos el pico máximo del sismo en la zona del epicentro y aún más para zonas más alejadas; y la considerable reducción de falsas alarmas. Adicionalmente la arquitectura propuesta incluye una administración post-evento que mejora la capacidad operativa, logística y de telecomunicaciones desde un solo nivel central, y al mismo tiempo, mantiene al usuario informado de centros de refugios cercanos, mejores rutas, rutas seguras para una mejor decisión. Abstract: Detecting disruptive events using COTS sensors like the ones embedded in smartphones is a difficult challenge but also an interesting opportunity. In this paper, we present a distributed, reliable, hierarchical and hard real-time system architecture of

CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome

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Shelly Rozen

2015-10-01

Full Text Available The highly conserved COP9 signalosome (CSN complex is a key regulator of all cullin-RING-ubiquitin ligases (CRLs, the largest family of E3 ubiquitin ligases. Until now, it was accepted that the CSN is composed of eight canonical components. Here, we report the discovery of an additional integral and stoichiometric subunit that had thus far evaded detection, and we named it CSNAP (CSN acidic protein. We show that CSNAP binds CSN3, CSN5, and CSN6, and its incorporation into the CSN complex is mediated through the C-terminal region involving conserved aromatic residues. Moreover, depletion of this small protein leads to reduced proliferation and a flattened and enlarged morphology. Finally, on the basis of sequence and structural properties shared by both CSNAP and DSS1, a component of the related 19S lid proteasome complex, we propose that CSNAP, the ninth CSN subunit, is the missing paralogous subunit of DSS1.

Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge.

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Alex J Mann

Full Text Available We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI intratracheal and intranasal challenge in a ferret model. Six groups of 6 ferrets were intranasally vaccinated twice, 21 days apart, with either placebo, antigen alone, CSN adjuvanted antigen, or TM-CSN adjuvanted antigen. Homologous and intra-subtypic antibody cross-reacting responses were assessed. Ferrets were inoculated intratracheally (all treatments or intranasally (CSN adjuvanted and placebo treatments only with clade 1 HPAI A/Vietnam/1194/2004 (H5N1 virus 28 days after the second vaccination and subsequently monitored for morbidity and mortality outcomes. Clinical signs were assessed and nasal as well as throat swabs were taken daily for virology. Samples of lung tissue, nasal turbinates, brain, and olfactory bulb were analysed for the presence of virus and examined for histolopathological findings. In contrast to animals vaccinated with antigen alone, the CSN and TM-CSN adjuvanted vaccines induced high levels of antibodies, protected ferrets from death, reduced viral replication and abrogated disease after intratracheal challenge, and in the case of CSN after intranasal challenge. In particular, the TM-CSN adjuvanted vaccine was highly effective at eliciting protective immunity from intratracheal challenge; serologically, protective titres were demonstrable after one vaccination. The 2-dose schedule with TM-CSN vaccine also induced cross-reactive antibodies to clade 2.1 and 2.2 H5N1 viruses. Furthermore ferrets immunised with TM-CSN had no detectable virus in the respiratory tract or brain, whereas there were signs of virus in the throat and lungs, albeit at significantly reduced levels, in CSN vaccinated animals. This study demonstrated for the first time that CSN and in particular TM-CSN adjuvanted intranasal vaccines have the potential to protect against significant

Validación de la escala para manía de la Universidad Nacional de Colombia usando el análisis de Rasch

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Ricardo Sánchez

2011-03-01

Conclusiones. En este primer estudio de la escala para manías usando el análisis de Rasch, se detectó mal ajuste y redundancia de algunos ítems. El síndrome maníaco no queda completamente evaluado por la escala. El instrumento podría mejorarse agregando síntomas depresivos.

Aulas-laboratorios de bajo costo, usando TIC

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Silvia E. Calderón

2015-01-01

Full Text Available En este trabajo se presentan los resultados de una propuesta educativa orientada a promover el desarrollo de un pensamiento critico y un mayor interes por las ciencias experimentales. Con este fin desarrollamos propuestas de proyectos educativos susceptibles de ser destinadas a las aulas y laboratorios de las escuelas secundarias y primeros anos de la universidad, que resaltan los aspectos metodologicos de las ciencias. Aqui, realizamos una compilacion de varios proyectos, que ilustran formas de incorporar las tecnologias de la informacion y la comunicacion (TIC en diversos experimentos de ciencias, muchos de ellos publicados individualmente anteriormente, y que en conjunto se pueden utilizar para implementar un aula-laboratorio de bajo costo. Con TIC hacemos referencia a la convergencia de computadoras, sistemas audiovisuales, Internet, telefonia, y diversos equipos que se integran con algunos de ellos. Los proyectos intentan integrar areas como fisica, matematica, quimica, informatica, arte, etc. y apuntan a que los estudiantes puedan responder a las preguntas: .Como sabemos esto?, .Por que creemos en aquello? Preguntas que ilustran la naturaleza del pensamiento cientifico. Nuestra contribucion mas significativa es haber desarrollado ≪aulas-laboratorios≫ de muy bajo costo, usando TIC. Con el advenimiento de programas como ≪Una Laptop por Nino≫ que se estan implementando en varios paises de Latinoamerica, resulta oportuno utilizar este recurso como base para generar laboratorios de bajo costo, que creemos pueden ser una herramienta util para mejorar el aprendizaje de las ciencias, incentivar vocaciones y contribuir a desarrollar un pensamiento critico, a la par de desarrollar habilidades con el uso de las TIC que pueden ser de utilidad en diversos ambitos academicos y laborales.

Producción de carbones ultralimpios usando flotación burbujeante y lixiviación con ácidos

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Juan Barraza

2009-01-01

Full Text Available Los carbones ultralimpios representan una importante materia prima para la elaboración de productos de alto valor agregado tales como fibra de carbono, electrodos, espumas de carbón, entre otros. En este trabajo, carbones ultralimpios con concentraciones menores a 0,50% de ceniza (p/p, base seca, bs se obtuvieron usando flotación burbujeante en columna y lixiviación con ácidos fluorhídrico (HF y nítrico (HNO3. Los contenidos de ceniza se redujeron desde 19,60 % en los carbones alimentados hasta 8,70 % en los carbones flotados usando tres etapas en serie en una columna de flotación. Al usar lixiviación química con HF 7,53M y HNO3 2,3M, los carbones presentaron contenidos de 1,42% de ceniza, 0,86% de azufre y 2,00% de materia mineral, mientras que cuando se usó un proceso combinado de flotación seguido de lixiviación ácida con HF 19,2M y HNO3 8,12M se obtuvo un carbón con 0,48 % de ceniza 0,71 % de azufre y 0,96 % de materia mineral. Sin embargo, al usar carbón original (no flotado a las mismas concentraciones ácidas utilizadas en el proceso combinado se produjo un carbón ultralimpio de contenido de ceniza 0,33%.

Corrección del factor de potencia en una carga no lineal utilizando filtro activo y control SVPWM

OpenAIRE

Arias Chablé, Enrique

2006-01-01

El presente trabajo de tesis tiene la finalidad fundamental de presentar el análisis y simulación de una topología de filtro activo de potencia controlado por Modulación de Ancho de Pulso, usando la técnica del Vector Espacio (Space Vector Pulse Wide Modulation, SVPWM), para corregir el factor de potencia de un sistema de distribución de energía eléctrica con una carga no lineal. En el primer capítulo se hace una revisión de los conceptos fundamentales de calidad de la e...

La Demanda Residencial por Energía Eléctrica en Chile

OpenAIRE

Claudio A Agostini; Cecilia Plottier; Eduardo Saavedra

2011-01-01

En un contexto de demanda creciente y oferta estocástica de energía en Chile se hace necesario conocer a cabalidad los determinantes de la demanda por energía eléctrica de los hogares - en particular su elasticidad precio - para así utilizar mecanismos de flexibilización de precios con miras a reducir posibles déficits de energía. Este trabajo estima la demanda de energía eléctrica residencial usando información de la Encuesta de Caracterización Socioeconómica Nacional (CASEN) 2006, siendo in...

APROXIMACIÓN AL LIDERAZGO DESDE LA CARACTERIZACIÓN DE REDES SOCIALES PRESENTES EN EL AULA

OpenAIRE

MARTHA RUTH MENDOZA TORRES

2008-01-01

Este artículo hace una reflexión sobre la vinculación entre el comportamiento de las redes sociales y el desarrollo en sus integrantes de capacidades de liderazgo, a través del aprendizaje derivado de la relación líder/grupo/contexto, promovido a su vez por las relaciones de vecindad o lógica del enjambre, lo que posibilita el diseño de acciones orientadas a desarrollar esas capacidades en estudiantes de carreras de negocios y presenta un ejemplo sobre como usando la metodología de caracte...

Signal compression in radar using FPGA

OpenAIRE

Enrique Escamilla Hemández; Víctor Kravchenko; Volodymyr Ponomaryov; Gonzalo Duchen Sánchez; David Hernández Sánchez

2010-01-01

El presente artículo muestra la puesta en práctica de hardware para realizar el procesamiento en tiempo real de la señal de radar usando una técnica simple, rápida basada en arquitectura de FPGA (Field Programmable Gate Array). El proceso incluye diversos procedimientos de enventanado durante la compresión del pulso del radar de apertura sintética (SAR). El proceso de compresión de la señal de radar se hace con un filtro acoplado. que aplica funciones clásicas y nuevas de enventanado, donde n...

¿El proceso de enfermería hace parte de la calidad del cuidado?

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MYRIAM ABAUNZA DE GONZÁLEZ

2007-12-01

Full Text Available El principal propósito de este artículo es dar respuesta al siguiente interrogante: ¿El proceso de enfermería hace parte de la calidad del cuidado? Para sustentar la respuesta a la pregunta, se parte de referenciar varios autores que han hecho estudios sobre la utilización del método científico, del método de solución de problemas y del proceso de atención de enfermería y su relación con la calidad del servicio y del cuidado de enfermería, al mismo tiempo que se introducen experiencias relacionadas con proyectos de investigación tipo NIPE y Grupos relacionados con el Dx, y experiencias de evaluación de servicios de enfermería en algunos hogares y hospitales en Colombia, México, Cuba y Chile, en donde se aprecia que el proceso de enfermería es el que define el concepto enfermero aplicado. Se concluye que el proceso de enfermería como parte fundamental del cuidado de enfermería, al acortar estancias, disminuir el número de complicaciones y evitar los reingresos, contribuye a mejorar la calidad de su servicio y la calidad de vida de los pacientes/usuarios.

Producción de carbones ultralimpios usando flotación burbujeante y lixiviación con ácidos

OpenAIRE

Barraza, Juan; Mejía, Isabel

2009-01-01

Los carbones ultralimpios representan una importante materia prima para la elaboración de productos de alto valor agregado tales como fibra de carbono, electrodos, espumas de carbón, entre otros. En este trabajo, carbones ultralimpios con concentraciones menores a 0,50% de ceniza (p/p, base seca, bs) se obtuvieron usando flotación burbujeante en columna y lixiviación con ácidos fluorhídrico (HF) y nítrico (HNO3). Los contenidos de ceniza se redujeron desde 19,60 % en los carbones alimentados ...

SÍNTESIS DE OXITOCINA EN FASE SÓLIDA USANDO DERIVADOS DE TERBUTOXICARBONILO Y FLUORENILMETOXICARBONILO

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Julio C Calvo

2010-08-01

Full Text Available La oxitocina, péptido cíclico cuya secuencia es CYIQNCPLG, fué el primer péptido de importancia biológica que pudo ser sintetizado. En este trabajo se compara la síntesis de la oxitocina usando resina p metilbenzhidrilamina (MBHA para la síntesis por estrategia t-Boc y resina Rink p-metilbenzhidrilamina (Rink MBHA para la síntesis por estrategia Fmoc, con altos rendimientos. El péptido crudo se ciclizó en una disolución acuosa de dimetilsulfóxido al 10%. La caracterización se llevó a cabo por espectrometría de masas y resonancia magnética nuclear, y se logró detectar la presencia de dos isómeros.

Medición de microdeformaciones en losas viales usando sensores de redes de Bragg en fibras ópticas

OpenAIRE

Vélez-Hoyos, Francisco Javier; Serpa-Imbet, Claudia Milena; Gómez-Cardona, Nelson Darío

2010-01-01

En este trabajo se presenta un método no invasivo para la medición de microdeformaciones en estructuras de concreto usando sensores de redes de Bragg en fibras ópticas adheridos a su superficie. Se realizan mediciones en losas viales de concreto bajo una carga estática de 10 kN, encontrándose una relación aproximada de 2 : 1 entre la deformación registrada por los sensores y los valores arrojados por una simulación computacional con el método de elementos finitos. Se propone el uso de estos s...

GRINDING OF HARDENED STEELS USING OPTIMIZED COOLING RECTIFICADO DE ACEROS ENDURECIDOS USANDO REFRIGERACIÓN OPTIMIZADA

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Manoel Cléber de Sampaio Alves

2008-06-01

Full Text Available Grinding – the final machining process of a workpiece – requires large amounts of cutting fluids for the lubrication, cooling and removal of chips. These fluids are highly aggressive to the environment. With the technological advances of recent years, the worldwide trend is to produce increasingly sophisticated components with very strict geometric and dimensional tolerances, good surface finish, at low costs, and particularly without damaging the environment. The latter requirement can be achieved by recycling cutting fluids, which is a costly solution, or by drastically reducing the amount of cutting fluids employed in the grinding process. This alternative was investigated here by varying the plunge velocity in the plunge cylindrical grinding of ABNT D6 steel, rationalizing the application of two cutting fluids and using a superabrasive CBN (cubic boron nitride grinding wheel with vitrified binder to evaluate the output parameters of tangential cutting force, acoustic emission, roughness, roundness, tool wear, residual stress and surface integrity, using scanning electron microscopy (SEM to examine the test specimens. The performance of the cutting fluid, grinding wheel and plunge velocity were analyzed to identify the best machining conditions which allowed for a reduction of the cutting fluid volume, reducing the machining time without impairing the geometric and dimensional parameters, and the surface finish and integrity of the machined components.La rectificación, proceso final de fabricación de una pieza, hace uso intenso de fluidos de corte con la finalidad de lubricación, refrigeración y remoción de astillas (imperfecciones. Sin embargo, estos fluidos son extremamente agresivos al medio. Con el avance tecnológico la tendencia mundial es producir piezas cada vez mas sofisticadas, con elevado grado de tolerancia geométrica, dimensional, con buen acabamiento superficial, con bajo costo y, principalmente, sin causar daños al

The Evolution of COP9 Signalosome in Unicellular and Multicellular Organisms.

Science.gov (United States)

Barth, Emanuel; Hübler, Ron; Baniahmad, Aria; Marz, Manja

2016-05-02

The COP9 signalosome (CSN) is a highly conserved protein complex, recently being crystallized for human. In mammals and plants the COP9 complex consists of nine subunits, CSN 1-8 and CSNAP. The CSN regulates the activity of culling ring E3 ubiquitin and plays central roles in pleiotropy, cell cycle, and defense of pathogens. Despite the interesting and essential functions, a thorough analysis of the CSN subunits in evolutionary comparative perspective is missing. Here we compared 61 eukaryotic genomes including plants, animals, and yeasts genomes and show that the most conserved subunits of eukaryotes among the nine subunits are CSN2 and CSN5. This may indicate a strong evolutionary selection for these two subunits. Despite the strong conservation of the protein sequence, the genomic structures of the intron/exon boundaries indicate no conservation at genomic level. This suggests that the gene structure is exposed to a much less selection compared with the protein sequence. We also show the conservation of important active domains, such as PCI (proteasome lid-CSN-initiation factor) and MPN (MPR1/PAD1 amino-terminal). We identified novel exons and alternative splicing variants for all CSN subunits. This indicates another level of complexity of the CSN. Notably, most COP9-subunits were identified in all multicellular and unicellular eukaryotic organisms analyzed, but not in prokaryotes or archaeas. Thus, genes encoding CSN subunits present in all analyzed eukaryotes indicate the invention of the signalosome at the root of eukaryotes. The identification of alternative splice variants indicates possible "mini-complexes" or COP9 complexes with independent subunits containing potentially novel and not yet identified functions. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Lei da gravitação universal e os satélites: uma abordagem histórico-temática usando multimídia

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Elvis Vilela Rodrigues

2012-01-01

Full Text Available Examina-se, neste artigo, o desenvolvimento de aulas de Física em que, usando-se uma multimídia, a Lei da Gravitação Universal é abordada de forma contextualizada a partir da História da Ciência e de um tema atual (os satélites. O objetivo foi examinar como estudantes de Ensino Médio aceitam e se envolvem nesse estudo. Usando uma abordagem metodológica qualitativa, a multimídia apresenta o que são e como funcionam os satélites artificiais, trazendo uma narrativa histórica desde as ideias de movimento do sistema planetário de Ptolomeu até as de Isaac Newton sobre o movimento dos corpos, culminando na Lei da Gravitação Universal. Entrevistas, observações de sala de aula e documentos produzidos pelos estudantes mostram que as imagens, os filmes e os textos contidos na multimídia enriquecem, de modo significativo, o conteúdo, facilitando o entendimento de conceitos da Física. A contextualização histórico-temática, por sua vez, produz maior envolvimento dos alunos no estudo da Física.

IMPLEMENTACIÓN DE UN SERVICIO EN LA WEB –MASHUP– PARA LA FUSIÓN DE IMÁGENES SATELITALES USANDO LA TRANSFORMADA RÁPIDA DE WAVELET HAAR

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Rubén Medina

2014-05-01

Full Text Available En este artículo se implementa un nuevo servicio en la Web que ofrece a los usuarios la posibilidad de realizar la fusión de imágenes de satélite provenientes de diferentes sensores remotos y/o con diferentes resoluciones espaciales. A lo largo del artículo tres temáticas importantes son abordadas. La primera temática corresponde al servicio Web, éste servicio es implementado usando software libre y cuenta con una sencilla interfaz donde el usuario puede interactuar y principalmente puede realizar una solicitud del servicio de fusión. Adicionalmente, en la aplicación Web se desarrolló un módulo que permite obtener datos georreferenciados de diferentes fuentes externas para crear un nuevo servicio (Mashup a través de las API’s, de manera rápida y fácil utilizando OpenStreetMaps. La segunda temática se ocupa del análisis de la transformada rápida de wavelet haar (TRWH, estos conceptos matemáticos se abordan a partir de un ejemplo usando una matriz que se descompone en coeficientes de detalle y de aproximación de segundo nivel. La última temática detalla la metodología propuesta, paso a paso, para realizar la fusión de imágenes usando la TRWH. Igualmente con el fin de determinar la eficiencia de la TRWH cinco wavelets diferentes fueron implementadas en Matlab para fusionar el mismo par de imágenes satelitales. Las imágenes resultantes fueron evaluadas tanto en la calidad espacial como en la espectral a través de cuatro índices. Los mejores resultados de la evaluación fueron obtenidos con la TRWH la cual preserva la riqueza espectral de la imagen multiespectral original y mejora su calidad espacial.

The COP9 signalosome controls jasmonic acid synthesis and plant responses to herbivory and pathogens.

Science.gov (United States)

Hind, Sarah R; Pulliam, Sarah E; Veronese, Paola; Shantharaj, Deepak; Nazir, Azka; Jacobs, Nekaiya S; Stratmann, Johannes W

2011-02-01

The COP9 signalosome (CSN) is a multi-protein complex that regulates the activities of cullin-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate proteins in order to target them for proteasomal degradation. The CSN is required for proper plant development. Here we show that the CSN also has a profound effect on plant defense responses. Silencing of genes for CSN subunits in tomato plants resulted in a mild morphological phenotype and reduced expression of wound-responsive genes in response to mechanical wounding, attack by Manduca sexta larvae, and Prosystemin over-expression. In contrast, expression of pathogenesis-related genes was increased in a stimulus-independent manner in these plants. The reduced wound response in CSN-silenced plants corresponded with reduced synthesis of jasmonic acid (JA), but levels of salicylic acid (SA) were unaltered. As a consequence, these plants exhibited reduced resistance against herbivorous M. sexta larvae and the necrotrophic fungal pathogen Botrytis cinerea. In contrast, susceptibility to tobacco mosaic virus (TMV) was not altered in CSN-silenced plants. These data demonstrate that the CSN orchestrates not only plant development but also JA-dependent plant defense responses. © 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd.

Liderazgo y cultura organizacional en Latinoamerica

OpenAIRE

Rivera González, Luis

2016-01-01

El presente estudio de corte descriptivo hace una revisión teórica de 68 artículos de 11 países de Latinoamérica con el fin de dar a conocer el panorama organizacional con relación a la cultura organizacional y el liderazgo en la región y cómo este ha ido evolucionando en el tiempo. La metodología utilizada se enfocó en un conteo de frecuencias usando el modelo de liderazgo y cultura organizacional de Bass y Avolio (Bass, 1999) permitiendo ordenar en tres estilos de liderazgo la información e...

Experiencias sorprendentes de química con indicadores de pH caseros

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Heredia Avalos, S.

2006-01-01

Full Text Available En este trabajo se describen varias experiencias sencillas relacionadas con las reacciones ácido-base. Todas ellas pueden realizarse con utensilios de cocina y usando sustancias baratas que pueden encontrarse fácilmente en un supermercado, una farmacia o en casa. En concreto, se describe la forma de obtener algunos indicadores de pH a partir de extractos vegetales o de medicamentos. Además, se proponen varias experiencias en las que se hace uso de estos indicadores con el fin de estudiar las reacciones ácido-base. Todas estas experiencias están enfocadas a alumnos de enseñanza secundaria.

Automated Image Sampling and Classification Can Be Used to Explore Perceived Naturalness of Urban Spaces.

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Roger Hyam

Full Text Available The psychological restorative effects of exposure to nature are well established and extend to just viewing of images of nature. A previous study has shown that Perceived Naturalness (PN of images correlates with their restorative value. This study tests whether it is possible to detect degree of PN of images using an image classifier. It takes images that have been scored by humans for PN (including a subset that have been assessed for restorative value and passes them through the Google Vision API image classification service. The resulting labels are assigned to broad semantic classes to create a Calculated Semantic Naturalness (CSN metric for each image. It was found that CSN correlates with PN. CSN was then calculated for a geospatial sampling of Google Street View images across the city of Edinburgh. CSN was found to correlate with PN in this sample also indicating the technique may be useful in large scale studies. Because CSN correlates with PN which correlates with restorativeness it is suggested that CSN or a similar measure may be useful in automatically detecting restorative images and locations. In an exploratory aside CSN was not found to correlate with an indicator of socioeconomic deprivation.

Bioinformatic analyses of kappa casein gene in mammalian ...

African Journals Online (AJOL)

Using a comparative genomic approach, we obtained 1797 bp of the CSN3 sequences from cattle, goat, horse, pig, rabbit and sheep. ... observed in phylogenetic tree of CSN3 gene which showed that the comparability of CSN3 gene sequences was highest between the goat and sheep and they evolved from a most recent ...

Sobre el estudio de la función cuadrática y su relación con el área de algunas figuras y su visualización usando Cabri II Plus

OpenAIRE

Vera Barrios, Dídimo

2013-01-01

Propuesta didáctica en donde se presentan algunas actividades dinámicas usando Cabri II Plus con el fin de relacionar algunos aspectos que tienen que ver con el área de algunas figuras y la función cuadrática.

AUTOMATIZACIÓN DE LA ARQUITECTURA DE COMPONENTES GENÉRICOS USANDO UML

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Noel Fuentes Ramírez

2006-04-01

Full Text Available

La arquitectura de componentes genéricos permite chequear la consistencia interna de sus elementos arquitectónicos (componentes y conectores a partir de las relaciones internas en sus respectivas estructuras, que pueden ser de inclusión y transformación. También permite verificar la conexión entre componentes y conectores a partir de las relaciones de transformación entre sus interfaces respectivas. Las ideas que se presentan aquí constituyen una propuesta para la automatización de la descripción de esta arquitectura usando el lenguaje de modelado unificado (UML a partir de la descripción formal de sus diagramas de clases y de secuencia, así como para el chequeo de la consistencia. En este artículo se muestra la aplicación de esta propuesta mediante una extensión de la herramienta Visual Paradigm, por medio de un módulo de software conectable.

Comercio exterior colombiano y su financiación con la banca local: un análisis a nivel de firma

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Sergio Restrepo

2014-07-01

Full Text Available En este trabajo se estima la elasticidad de las exportaciones y las importaciones al crédito otorgado por la banca comercial, usando información cruzada a nivel de firmas en Colombia. Replicando la metodología empírica de Paravisini et al. (2011, se encontró que una reducción del crédito de 10% reduce el valor exportado e importado en 3,95% y 5,12% y el volumen en 2,33% y 3,63%, respectivamente. Se hace uso de la metodología de panel de datos con variables instrumentales para controlar por otros factores que afectan la demanda de crédito por parte de las firmas.

Comercio exterior colombiano y su financiación con la banca local: un análisis a nivel de firma

Directory of Open Access Journals (Sweden)

Sergio Restrepo

2014-01-01

Full Text Available En este trabajo se estima la elasticidad de las exportaciones y las importaciones al crédito otorgado por la banca comercial, usando información cruzada a nivel de firmas en Colombia. Replicando la metodología empírica de Paravisini et al. (2011, se encontró que una reducción del crédito de 10% reduce el valor exportado e importado en 3,95% y 5,12% y el volumen en 2,33% y 3,63%, respectivamente. Se hace uso de la metodología de panel de datos con variables instrumentales para controlar por otros factores que afectan la demanda de crédito por parte de las firmas.

Efeito de instruções usando DVD-ROM no desempenho técnico de massoterapia miofascial e sua retenção

OpenAIRE

Luiz Francisco Cachoni

2014-01-01

Contextualização: Existem poucas investigações sobre recursos didáticos modernos para o ensino de habilidades técnicas de massoterapia. Objetivo: Avaliar o efeito de instruções usando filme no formato DVD associado ao ensino tradicional (aula expositiva com demonstração do instrutor em um voluntário), no aprendizado e na retenção de massagem miofascial (MM). Método: Estudo retrospectivo e duplo cego. Uma fisioterapeuta experiente que atuou como professora (cega ao objetivo do estudo) e 60 fis...

Effect of the clinical support nurse role on work-related stress for nurses on an inpatient pediatric oncology unit.

Science.gov (United States)

Chang, Ann; Kicis, Jennifer; Sangha, Gurjit

2007-01-01

High patient acuity, heavy workload, and patient deaths can all contribute to work-related stress for pediatric oncology nurses. A new leadership role, the clinical support nurse (CSN), was recently initiated on the oncology unit of a large Canadian pediatric hospital to support frontline staff and reduce some of the stresses related to clinical activity. The CSN assists nurses with complex patient care procedures, provides hands-on education at the bedside, and supports staff in managing challenging family situations. This study explores the effect of the CSN role on the nurses' work-related stress using the Stressor Scale for Pediatric Oncology Nurses. A total of 58 nurses participated in this study for a response rate of 86%. The results show that the intensity of work-related stress experienced by nurses in this study is significantly less (P < .001) on shifts staffed with a CSN compared with shifts without a CSN.

Ddb1 controls genome stability and meiosis in fission yeast

DEFF Research Database (Denmark)

Holmberg, Christian Henrik; Fleck, Oliver; Hansen, H. A.

2005-01-01

The human UV-damaged DNA-binding protein Ddb1 associates with cullin 4 ubiquitin ligases implicated in nucleotide excision repair (NER). These complexes also contain the signalosome (CSN), but NER-relevant ubiquitination targets have not yet been identified. We report that fission yeast Ddb1......, Cullin 4 (Pcu4), and CSN subunits Csn1 and Csn2 are required for degradation of the ribonucleotide reductase (RNR) inhibitor protein Spd1. Ddb1-deficient cells have >20-fold increased spontaneous mutation rate. This is partly dependent on the error-prone translesion DNA polymerases. Spd1 deletion...... substantially reduced the mutation rate, suggesting that insufficient RNR activity accounts for ~50% of observed mutations. Epistasis analysis indicated that Ddb1 contributed to mutation avoidance and tolerance to DNA damage in a pathway distinct from NER. Finally, we show that Ddb1/Csn1/Cullin 4-mediated Spd1...

MODELACIÓN NUMÉRICA DE PROCESOS DE ESTERILIZACIÓN TÉRMICA DE ALIMENTOS USANDO VOLUMENES DE CONTROL: APROXIMACIÓN CILÍNDRICA

OpenAIRE

HÉCTOR J. CIRO-VELÁSQUEZ; CARLOS GONZÁLEZ; EDUARD GARCÍA

2009-01-01

Un proceso de esterilización térmica de alimentos fue modelado usando la técnica de diferenciación finita aplicada a volúmenes de control. El modelo de simulación fue desarrollado en coordenadas cilíndricas con un ejemplo de aplicación tomando como referencia un producto cárnico (carne de res). Los resultados de la simulación mostraron que el algoritmo desarrollado es independiente de la red nodal seleccionada, permitiendo cuantificar las curvas de penetración de calor en el punto crítico del...

Análisis de un sistema de almacenamiento de energía térmica usando cloruro de magnesio hexahidratado

Directory of Open Access Journals (Sweden)

Andrés Felipe Macía

2010-01-01

Full Text Available Se simuló el comportamiento del cloruro de magnesio hexahidratado (MgCl2*6H2O como almacenador de energía térmica, que posee una temperatura de transición de fase de 117ºC; lo que lo convierte en un material con gran potencial en el área de las aplicaciones de mediana temperatura (aplicaciones industriales. Se desarrolló una simulación CFD usando el software FLUENT para describir la fusión/solidificación de la sal hidratada. Se observó el efecto del uso de aletas y las fuerzas boyantes producidas por los efectos gravitacionales.

Clasificación digital de masas nubosas a partir de imágenes meteorológicas usando algoritmos de aprendizaje de máquina

Directory of Open Access Journals (Sweden)

Salomón Einstein Ramírez-Fernández

2014-01-01

Full Text Available La identificación exacta de nubes precipitantes es una tarea difícil. En el presente trabajo se aplicaron los algoritmos Máquinas de Soporte Vectorial, Árboles de Decisión y Bosques Aleatorios para discriminar entre nubes precipitantes y nubes no precipitantes, a partir de una imagen meteorológica del satélite GOES-13 que cubre el territorio colombiano. El objetivo del trabajo fue evaluar el desempeño de los algoritmos de aprendizaje de máquina (ML, para la clasificación digital de masas nubosas, en términos de la exactitud temática de la clasificación usando como referencia el algoritmo convencional distancia de Mahalanobis. Los resultados muestran que los algoritmos ML proporcionan una clasificación de masas de nubes más exacta que la obtenida por algoritmos convencionales. La mejor exactitud fue obtenida usando Bosques Aleatorios (RF, con una exactitud temática global de 97%. Adicionalmente, la clasificación obtenida con RF fue comparada pixel a pixel con estimaciones de precipitación de la NASA Tropical Rainfall Measurement Mission (TRMM obteniendo una exactitud global del 94%. De acuerdo con este estudio, los algoritmos ML pueden ser usados para mejorar los actuales métodos de identificación de nubes precipitantes.

Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.

Science.gov (United States)

Scherer, Paul C; Ding, Yan; Liu, Zhiqing; Xu, Jing; Mao, Haibin; Barrow, James C; Wei, Ning; Zheng, Ning; Snyder, Solomon H; Rao, Feng

2016-03-29

The family of cullin-RING E3 Ligases (CRLs) and the constitutive photomorphogenesis 9 (COP9) signalosome (CSN) form dynamic complexes that mediate ubiquitylation of 20% of the proteome, yet regulation of their assembly/disassembly remains poorly understood. Inositol polyphosphates are highly conserved signaling molecules implicated in diverse cellular processes. We now report that inositol hexakisphosphate (IP6) is a major physiologic determinant of the CRL-CSN interface, which includes a hitherto unidentified electrostatic interaction between the N-terminal acidic tail of CSN subunit 2 (CSN2) and a conserved basic canyon on cullins. IP6, with an EC50 of 20 nM, acts as an intermolecular "glue," increasing cullin-CSN2 binding affinity by 30-fold, thereby promoting assembly of the inactive CRL-CSN complexes. The IP6 synthase, Ins(1,3,4,5,6)P5 2-kinase (IPPK/IP5K) binds to cullins. Depleting IP5K increases the percentage of neddylated, active Cul1 and Cul4A, and decreases levels of the Cul1/4A substrates p27 and p21. Besides dysregulating CRL-mediated cell proliferation and UV-induced apoptosis, IP5K depletion potentiates by 28-fold the cytotoxic effect of the neddylation inhibitor MLN4924. Thus, IP5K and IP6 are evolutionarily conserved components of the CRL-CSN system and are potential targets for cancer therapy in conjunction with MLN4924.

Análisis del aprendizaje usando el nivel de la incertidumbre en la adquisición de conocimiento

OpenAIRE

Huapaya, Constanza Raquel; Lizarralde, Francisco Ángel José; Arona, Graciela; Vivas, Jorge

2013-01-01

Como continuación de la investigación sobre el uso de la Minería de Datos Educacional (MDE) para descubrir nuevo conocimiento basado en datos de la actividad del estudiante se ha elegido estudiar la incertidumbre en la medición de la adquisición de conocimiento a fin de mejorar la estimación de perfiles cognitivos del estudiante sobre los cuales se está investigando desde hace dos años. El conocimiento adquirido por los estudiantes es, en general, imperfecto. El grado de profundidad en la ...

Does Informal Caregiving Lead to Parental Burnout? Comparing Parents Having (or Not) Children With Mental and Physical Issues.

Science.gov (United States)

Gérain, Pierre; Zech, Emmanuelle

2018-01-01

Introduction: Parenting a child with special needs (CSN) may be an important challenge. Previous research has highlighted an increased risk of parental burnout among parents caring for their CSN. Yet, these studies only focused on children with specific issues and did not consider the wide variety of CSN. There is thus a need to take a more global approach to assessing the impact of caring for a CSN on parental burnout. In addition, the impact on parental burnout of personality and parenting (dis)agreement needs to be measured to have a better understanding of parent-caregivers' (PCgs) burnout. Method: An online survey was completed by a large sample of parents from which a subsample of PCgs was identified. Results: T -tests highlighted significantly more parental burnout among parents of CSN. However, further analyses showed that parents with only one child with one special need did not experience significantly more burnout than parents with typical children. The significant difference lay in the presence of comorbidity or the presence of multiple CSN in the family. Hierarchical regressions showed an important impact of Neuroticism for every burnout facet, along with co-parenting (dis)agreement. Subjective consequences of having to care for a CSN were also related to the burnout facets of both emotional exhaustion and emotional distancing. Discussion: The presence of comorbidity and of multiple CSN in the family were related to more PCg burnout, emphasizing the need to consider these situations in further research. The role of neuroticism in PCg burnout confirms previous research both in parental and professional contexts. Parenting (dis)agreement also highlights the importance of dyadic support among parents. Finally, the importance of subjective aspects suggests that parental perception of their situation remains a central element in understanding the consequences of caregiving.

¿CÓMO SE HACE UN ANÁLISIS DEL ENTORNO ECONÓMICO EMPRESARIAL?

Directory of Open Access Journals (Sweden)

Carlos Parodi Trece

2010-08-01

Full Text Available La adecuada interpretación de la evolución de la economía constituye una herramienta útil para mejorarla toma de decisiones empresariales. El objetivo del artículo es explicar, con ejemplos aplicados a larealidad económica actual, cómo se hace un análisis del entorno económico y cómo este sirve para laplanificación estratégica empresarial. Para ello, previa explicación conceptual del marco general, sedefinen el producto interno bruto, la inflación y la brecha externa como indicadores de resultados, clavesen el «lenguaje» usado por los analistas. Son indicadores económicos, relacionados entre sí, que dependende la política económica interna y de choques exógenos, definidos estos últimos como eventos que estánfuera de las manos de los diseñadores de la política económica, pero que influyen en las tres variablesmencionadas, como, por ejemplo, la crisis financiera internacional. A continuación sigue la formalizaciónpor medio de las identidades macroeconómicas, para finalizar explicando «cómo va la economía» mediantelas mismas; así como, la relación entre el entorno económico interno con el externo. Acercar la economíaa la empresa debe ser una prioridad en un contexto cada vez más integrado, caracterizado por el hecho deque lo positivo y lo negativo de lo que ocurre en la economía mundial es transmitido, mediante diversoscanales, a las empresas ubicadas en distintos países. De ahí que las empresas deban ampliar su visión,pues el entorno económico no solo incluye lo que ocurre dentro del país, sino, cada vez con mayorrelevancia, el devenir de la economía mundial.

Estructura y diversidad genética en vacas Holstein de Antioquia usando un polimorfismo del gen bGH

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Juan Rincon F.

2013-03-01

Full Text Available Objetivo. Determinar las frecuencias alélicas y genotípicas del polimorfismo del intrón 3 del gen bGH y estimar algunos parámetros de estructura poblacional en ganado Holstein. Materiales y métodos. El estudio se realizó con 1366 vacas Holstein en 120 hatos de 11 municipios del departamento de Antioquia. Se extrajo DNA por el método de Salting out y la genotipificación se realizó usando la técnica de PCR-RFLPs. La diversidad genética se determinó mediante la comparación de las heterocigosidades, El equilibrio de Hardy-Weinberg (HW y la diferenciación genética entre las poblaciones se realizó usando el software Arlequín 2.0 Las frecuencias alélicas y genotípicas se evaluaron mediante el paquete estadístico SAS®. Resultados. Las frecuencias genotípicas encontradas fueron 0.764 (+/+, 0.223 (+/- y 0.013 (-/- y las frecuencias alélicas 0.876 (+ y 0.124 (-. No se encontraron desviaciones del Equilibrio de Hardy Weinberg en ninguna de las subpoblaciones. La diversidad genética determinada mediante la comparación de las heterocigosidades fue relativamente baja entre poblaciones pero al interior de estas no. El valor de FST de toda la población fue de 0.0068 y significativo (p<0.05, algunos FST pareados también lo fueron, tomando valores desde 0.0 a 0.13. Los estadísticos FIT y FIS no fueron significativos. Conclusiones. El gen bGH es un candidato interesante para evaluar características de importancia económica ya que no parece haber sido sometido a selección directa, presenta una variabilidad media en las poblaciones, observándose diferenciación genética significativa entre distintos municipios, producto de los diferentes sistemas de producción y acceso a las biotecnologías.

Divergence at the casein haplotypes in dairy and meat goat breeds.

Science.gov (United States)

Küpper, Julia; Chessa, Stefania; Rignanese, Daniela; Caroli, Anna; Erhardt, Georg

2010-02-01

Casein genes have been proved to have an influence on milk properties, and are in addition appropriate for phylogeny studies. A large number of casein polymorphisms exist in goats, making their analysis quite complex. The four casein loci were analyzed by molecular techniques for genetic polymorphism detection in the two dairy goat breeds Bunte Deutsche Edelziege (BDE; n=96), Weisse Deutsche Edelziege (WDE; n=91), and the meat goat breed Buren (n=75). Of the 35 analyzed alleles, 18 were found in BDE, and 17 in Buren goats and WDE. In addition, a new allele was identified at the CSN1S1 locus in the BDE, showing a frequency of 0.05. This variant, named CSN1S1*A', is characterized by a t-->c transversion in intron 9. Linkage disequilibrium was found at the casein haplotype in all three breeds. A total of 30 haplotypes showed frequencies higher than 0.01. In the Buren breed only one haplotype showed a frequency higher than 0.1. The ancestral haplotype B-A-A-B (in the order: CSN1S1-CSN2-CSN1S2-CSN3) occurred in all three breeds, showing a very high frequency (>0.8) in the Buren.

Mission IRRS to Spain. First mission of this type realised in the world

International Nuclear Information System (INIS)

Lentijo, J. C.; Mellado, I.

2008-01-01

The IRRS (Integrated Regulatory Review Service) mission to the Spanish Nuclear Safety Council (CSN), which took place from January 28 until February 8, has been the first integrated review of a regulatory body that includes all the aspects on nuclear safety radiation protection and security of all the facilities and activities under CSN responsibility. The review team was composed of eighteen experts from fifteen member sates, two observers, three IAEA officers and an administrative assistant, which have performed an exhaustive analysis of the Spanish regulatory system, including the legal and governmental infrastructure, the functions, responsibilities an organization of the CSN, the regulations and standards, and the assessment and inspection activities. The team members have interviewed different stake holders (public administrations, technical support organizations and licensees) and have observed several CSN inspections to different facilities as well. From the CSN point of view, the results of the IRRS mission are very positive. The relevant efforts devoted to prepare it, mainly the self-assessment process and the action plan established for implementing the improvement opportunities, have benefited the whole regulatory system and practices, being not the least the updating of the regulations and standards and the development of a CSN management system according to the IAEA requirement GS-R-3. (Author)

Casein SNP in Norwegian goats: additive and dominance effects on milk composition and quality

Science.gov (United States)

2011-01-01

Background The four casein proteins in goat milk are encoded by four closely linked casein loci (CSN1S1, CSN2, CSN1S2 and CSN3) within 250 kb on caprine chromosome 6. A deletion in exon 12 of CSN1S1, so far reported only in Norwegian goats, has been found at high frequency (0.73). Such a high frequency is difficult to explain because the national breeding goal selects against the variant's effect. Methods In this study, 575 goats were genotyped for 38 Single Nucleotide Polymorphisms (SNP) located within the four casein genes. Milk production records of these goats were obtained from the Norwegian Dairy Goat Control. Test-day mixed models with additive and dominance fixed effects of single SNP were fitted in a model including polygenic effects. Results Significant additive effects of single SNP within CSN1S1 and CSN3 were found for fat % and protein %, milk yield and milk taste. The allele with the deletion showed additive and dominance effects on protein % and fat %, and overdominance effects on milk quantity (kg) and lactose %. At its current frequency, the observed dominance (overdominance) effects of the deletion allele reduced its substitution effect (and additive genetic variance available for selection) in the population substantially. Conclusions The selection pressure of conventional breeding on the allele with the deletion is limited due to the observed dominance (overdominance) effects. Inclusion of molecular information in the national breeding scheme will reduce the frequency of this deletion in the population. PMID:21864407

Implementación de un mantenimiento basado en la condición usando modelado y simulación: caso de estudio de un motor sin-crónico de imanes permanentes

Directory of Open Access Journals (Sweden)

Jabid Quiroga Méndez

2011-05-01

Full Text Available Este artículo introduce la arquitectura de un CBM (mantenimiento basado en la condición en una aplicación eléctrica. La detección de fallas de manera oportuna y eficiente constituye uno de los retos más importantes asociados al CBM y el enfoque basado en modelos en el medio para conseguirlo. Un caso de estudio en un motor sincrónico de imanes permanentes (PMSM es ejecutado para ilustrar cómo el modelado es utilizado en la implementación de un CBM. El monitoreo fue implementado en tiempo real usando Matlab® y dSpace®. Se emplea como indicadora de falla la diferencia entre los valores de la componente secuencial negativa para las corrientes predichas usando una red neuronal multicapa y la corriente obtenida del motor. Resultados experimentales demostraron la efectividad del modelo propuesto en la detección de la falla de cortocircuito en el estator en distintos niveles de severidad y carga, obteniendo una confiabilidad en la detección mayor al 95%.

Variantes del problema del cartero mixto que se pueden resolver usando programación lineal

Directory of Open Access Journals (Sweden)

Francisco Javier Zaragoza Martínez

2012-07-01

Full Text Available Dada una gráfica mixta y conexa con costos en sus aristas y arcos, el problema del cartero mixto consiste en encontrar un circuito cerrado de la gráfica mixta que recorra sus aristas y arcos a costo mínimo. Se sabe que este problema es NP-duro. Sin embargo, bajo ciertas condiciones adicionales, el problema se puede resolver en tiempo polinomial usando programación lineal, en otras palabras, los poliedros correspondientes son enteros. Algunas de estas condiciones son: la gráfica mixta es serie paralelo o la gráfica mixta tiene grado total par en todos sus vértices. Además, mostramos que si agregamos la restricción adicional de que cada arista se recorra exactamente una vez entonces el problema se puede resolver en tiempo polinomial si el conjunto de arcos forma un bosque. Palabras clave: Gráfica mixta, problema de cartero, programación lineal. Mathematics Subject Classification: 05C45, 90C35.

Extração do óleo de manjericão usando fluido supercrítico: analise experimental e matemática

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Nídia Alves de Barros

2014-01-01

Full Text Available O óleo essencial de manjericão (Ocimum basilicum L. é valorizado no mercado internacional e amplamente usado nas indústrias de condimentos, cosméticos e medicinais. Entre todos os processos que podem ser aplicados na obtenção do óleo, a extração usando fluido supercrítico (EFS pode ser um método seletivo e eficiente, dependendo das condições operacionais, como temperatura e pressão, que precisam ser otimizadas. O objetivo deste estudo foi comparar a eficiência da extração supercrítica, utilizando planejamento experimental, na extração do óleo de manjericão com os métodos convencionais (hidrodestilação e soxhlet. Para a realização da parte experimental, foi utilizado dióxido de carbono como solvente para a EFS e hexano, para aplicação no soxhlet. Foi realizado um delineamento central composto rotacional (DCCR, aplicando três pressões (100, 200 e 300 bar e três temperaturas (30, 40 e 50ºC. Através da hidrodestilação, obteve-se o menor rendimento (0,26%, usando o Soxhlet, o rendimento foi de 2,39% sendo superior, comparado á EFS, que foi de 0,43%. O DCCR mostrou que, para otimizar o processo, é necessário aumentar a pressão e a temperatura para o alcance de maiores rendimentos. Foi possível constatar que o modelo matemático representou bem o processo de extração, propiciando o "scale-up" deste.

Desarrollo de herramienta de gestión de proyectos RUP usando metodologías Scrum + XP : gestión del proyecto y requisitos

OpenAIRE

Molina Romero, Javier; Quishpi Betún, Luis

2016-01-01

Una de las principales causas por las que los proyectos de desarrollo software fracasan es la ausencia de metodología en su desarrollo. La motivación que hay detrás de este proyecto es el desarrollo de una aplicación web usando la metodología Rational Unified Process (RUP) y aprender, en una situación real, cómo desarrollar utilizando las metodologías Scrum + XP. El principal objetivo de este proyecto es el seguimiento y documentación de una aplicación web para gestionar proyectos mediant...

The COP9 signalosome converts temporal hormone signaling to spatial restriction on neural competence.

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Yi-Chun Huang

2014-11-01

Full Text Available During development, neural competence is conferred and maintained by integrating spatial and temporal regulations. The Drosophila sensory bristles that detect mechanical and chemical stimulations are arranged in stereotypical positions. The anterior wing margin (AWM is arrayed with neuron-innervated sensory bristles, while posterior wing margin (PWM bristles are non-innervated. We found that the COP9 signalosome (CSN suppresses the neural competence of non-innervated bristles at the PWM. In CSN mutants, PWM bristles are transformed into neuron-innervated, which is attributed to sustained expression of the neural-determining factor Senseless (Sens. The CSN suppresses Sens through repression of the ecdysone signaling target gene broad (br that encodes the BR-Z1 transcription factor to activate sens expression. Strikingly, CSN suppression of BR-Z1 is initiated at the prepupa-to-pupa transition, leading to Sens downregulation, and termination of the neural competence of PWM bristles. The role of ecdysone signaling to repress br after the prepupa-to-pupa transition is distinct from its conventional role in activation, and requires CSN deneddylating activity and multiple cullins, the major substrates of deneddylation. Several CSN subunits physically associate with ecdysone receptors to represses br at the transcriptional level. We propose a model in which nuclear hormone receptors cooperate with the deneddylation machinery to temporally shutdown downstream target gene expression, conferring a spatial restriction on neural competence at the PWM.

Modelos de pérdida de masa de acero por corrosión atmosférica en Colombia usando inteligencia computacional

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Esteban Velilla

2009-01-01

Full Text Available Con el fin de clasificar la corrosividad de las diferentes atmósferas colombianas, como parte de un proyecto de investigación extenso [1], se expusieron placas de acero al carbono en 21 estaciones distribuidas a lo largo de la infraestructura eléctrica del país (líneas de transmisión y subestaciones. En estas estaciones se midieron entre otros, el tiempo de humectación y la deposición de sulfatos y cloruros durante 12 meses; además, bimensualmente se tomaban placas de acero para medir en laboratorio la pérdida de masa sufrida por estas durante el tiempo de exposición. La clasificación de las 21 estaciones se hizo en 4 grupos, considerando: el tiempo de humectación, contenidos de cloruros y sulfatos, la altura sobre el nivel del mar y el tiempo de exposición de las placas; variables consideradas linealmente independientes según la técnica de descomposición en valores singulares (SVD realizada. El criterio utilizado para la clasificación fue el de similitud de las variables utilizando la norma Euclidiana considerada en la red neuronal no supervisada tipo Kohonen. Adicionalmente, se implementaron modelos para la pérdida de masa del acero para cada uno de los grupos usando redes neuronales (RN tipo Feed-Forward, definiéndose como entradas las variables antes mencionadas y como única salida la pérdida de masa. Complementariamente se presenta una comparación entre el modelo de RN para el grupo 1, con otros modelos obtenidos usando Algoritmos Genéticos (AG y el método Simplex.

Hardware reconfigurable para la reconstrucción de videos transmitidos por un mazo de fibras incoherente

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Pablo Montejo Valdés

2013-04-01

Full Text Available La transmisión de imágenes mediante mazos de fibras ópticas no coherentes (IOFB necesita información sobre la posición de cada fibra para ser usada en la reconstrucción de la imagen original. Otro importante requerimiento es poseer suficiente memoria para almacenar la imagen durante su reconstrucción y durante su retransmisión. La mayoría de las veces estos aspectos obligan el uso de memoria externa si se utilizan FPGAs en el sistema. Este trabajo presenta una solución a este problema. Se propone un sistema en un chip capaz de almacenar la información necesaria y las imágenes sobre las que se está trabajando usando un FPGA de bajo costo. Se presentan dos soluciones y se implementa la que resulta más ventajosa. Los resultados son discutidos. El uso de este método hace posible transmitir  video usando IOFB y reconstruir las imágenes originales casi en tiempo real, debido a su baja latencia. Esta propuesta podría utilizarse en sistemas autónomos sacando ventaja de su nivel de compactación, fiabilidad y bajo costo.

Implementação da Técnica de Dessorção Térmica Programada (TPD) usando Espectrometria de Massa Quadrupolo

OpenAIRE

Barreto, Ana Marta Fortunato

2011-01-01

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do Grau de Mestre em Engenharia Física O projecto “Implementação da Técnica de Dessorção Térmica Programada (TPD) usando Espectrometria de Massa Quadrupolo”, apresentado nesta Dissertação de Mestrado em Engenharia Física, surgiu como uma proposta de requalificação ao aparelho de análise de superfícies Multitécnica. A dessorção térmica é o fenómeno que permite a separação física de ...

Análisis de materiales con haces de iones generados por un acelerador electrostático

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Climent Font, A.

2000-08-01

Full Text Available An electrostatic accelerator is a very versatile tool for the analysis of the materials elemental composition by means of ion beam based analytical techniques. These techniques known as IBA (ion beam analysis are widely used as a quantitative and non destructive characterization of almost any material down to depth of 10 μm below the surface and with a surface resolution from 2 to 20 nm. Their applications cover a wide range of areas such as: materials science, microelectronics, environmental studies, biomedical sciences, art and archaeology, etc. In this work the general physical principles of IBA are reviewed and its capabilities are illustrated with a selection of examples.

Un acelerador electrostático es una herramienta muy versátil para analizar materiales mediante las técnicas de haces de iones. Estas técnicas, conocidas como técnicas IBA (ion beam analysis, son ampliamente utilizadas para la caracterización cuantitativa y no destructiva de la estructura y la composición de la zona próxima a la superficie de cualquier material, hasta profundidades de 10 μm y con resolución superficial de 2 a 20 nm. Sus aplicaciones abarcan muchos campos, entre los que destacan: ciencia de materiales, microelectrónica, metalurgia, mineralogía, estudios medioambientales, ciencias biomédicas, arte y arqueología, etc. En este trabajo se revisan los principios físicos de las técnicas IBA y algunas de sus capacidades analíticas se ilustran con una selección de ejemplos.

The Spanish National Dose Registry and Spanish radiation passbooks

International Nuclear Information System (INIS)

Hernandez, A.; Martin, A.; Villanueva, I.; Amor, I.; Butragueno, J.L.

2001-01-01

The Spanish National Dose Registry (BDN) is the Nuclear Safety Council's (CSN) national database of occupational exposure to radiation. Each month BDN receives records of individual external doses from approved dosimetry services. The dose records include information regarding the occupational activities of exposed workers. The dose information and the statistical analysis prepared by the BDN are a useful tool for effective operational protection of occupationally exposed workers and a support for the CSN in the development and application of the ALARA principle. The Spanish radiation passbook was introduced in 1990 and since then CSN, as regulatory authority, has required that all outside workers entering controlled areas should have radiation passbooks. Nowadays, CSN has implemented improvements in the Spanish radiation Passbooks, taking into account previous experience and Directive 96/29/EURATOM. (author)

Simulación de la señalización de un usuarío móvil y un usuario fijo usando simulación de la señalización de un usuario móvil y un usuario fijo usandosimulación de la señalización de un usuario móvil y un usuario fijo usando simulación de la señalización de un usuario móvil y un usuario fijo usando ss7

OpenAIRE

Lopez Masabanda, Reina Azucena; Escalante Guzman, Betsy Rosa; Medina Moreira, Washington

2014-01-01

El presente proyecto consiste en realizar la simulación de la señalización entre un usuario de telefonía móvil y un usuario de telefonía fija usando el protocolo SS7, el cual ilustrará el proceso de una llamada. El software a utilizar, conocido como OMNET ++, es un simulador discreto de redes, usado habitualmente para modelar el tráfico de redes de telecomunicaciones, protocolos, sistemas multiprocesadores y distribuidos, que permite representar de manera real diferentes tipos de procesos de ...

Experts Complete IAEA Follow-up Review of Spanish Nuclear Regulatory Authority

International Nuclear Information System (INIS)

2011-01-01

Full text: Nuclear safety experts today concluded an eight-day mission to review Spain's nuclear regulator, the Nuclear Safety Council (CSN). At the request of the Spanish Government, the International Atomic Energy Agency assembled a peer-review team of five high-level regulatory experts from four nations and two IAEA staff members to conduct a follow-up assessment of an Integrated Regulatory Review Service (IRRS) mission conducted in 2008. This follow-up IRRS mission examined CSN's progress in acting upon the recommendations and suggestions made during the 2008 IRRS mission and reviewed the areas of significant regulatory changes since that review. Both reviews covered safety and security regulatory aspects of all facilities and activities in Spain. The first mission reviewed Spain's regulatory framework against IAEA Safety Standards and fostered the exchange of information and experience on safety regulation. The mission also included a peer review of the security activities within the regulatory framework. IRRS team leader Luis Reyes, Senior Executive of the US Nuclear Regulatory Commission, said today, 'In 2008, the mission found particular strengths in CSN's policy, its regulatory framework and its regulatory activities. We made a number of suggestions and recommendations for further improvement of the regulatory framework. CSN should be commended for the significant amount of efforts in addressing all the findings identified in 2008 mission.' The review team found that CSN has made significant progress toward improving its regulatory activities. Most of the findings identified in the 2008 report have been effectively addressed and therefore can be considered closed. Additional findings are being addressed in accordance with a comprehensive and systematic action plan, in particular efforts to revise the CSN Statute. Complementing the CSN strengths identified during the 2008 mission, the 2011 IRRS team noted the following strengths: Improvements in regulatory

Esquema de redundancia y distribución de carga de alta disponibilidad para la prestación de telefonía ip usando sip (junio 2009)

OpenAIRE

PARRA L., ANDRÉS; GUERRERO, FABIO G.

2010-01-01

En este artículo se presenta un esquema de distribución de carga y redundancia en la infraestructura de un ISP (Internet Service Provider) para la prestación de servicios de telefonía IP (ITSPs) sobre Internet usando el protocolo SIP (Session Initiation Protocol) garantizando niveles de acceso al servicio similares a la PSTN (Public Switched Telephone Network) y brindando una infraestructura de red escalable. La solución se plantea en tres partes: redundancia del servicio y distribución de ca...

PRODUCCIÓN DE BEBIDAS USANDO SORGO MALTEADO COMO MATERIA PRIMA PARA ENFERMOS CELIACOS

Directory of Open Access Journals (Sweden)

Irenia Gallardo

2013-01-01

Full Text Available La presente investigación trata los principales aspectos relacionados con la enfermedad celíaca, que es la que estimula a trabajar en la búsqueda de alternativas para producir alimentos a partir de otras fuentes que no sean los cereales tradicionales. El trabajo aborda el estudio de la obtención de dos bebidas, cerveza sin alcohol (malta y cerveza, a partir de sorgo blanco UDG-110 malteado. Para la producción de maltina, se hicieron experimentos basados en resultados preliminares, donde se determinaron las mejores relaciones de Malta Clara/Solución, Malta Clara/Malta total y Caramelo/Malta Total. Para la obtención de cerveza se hace un estudio preliminar a partir de la combinación de malta de sorgo y enzimas amilasas. Los resultados son satisfactorios, ya que las bebidas obtenidas tienen propiedades similares a las que se venden en el mercado, permitiendo acotar los parámetros para establecer una tecnología para la obtención de maltina y cerveza.

Validação de simulações combinadas usando programas de simulação de energia do edifício e programas de transferência de calor, ar e umidade em componentes construtivos

NARCIS (Netherlands)

Costola, D.; Blocken, B.J.E.; Hensen, J.L.M.

2011-01-01

Desempenho higrotérmico dos edifícios tem sido estudado usando uma variedade de programas de computador, os quais consideram determinados domínios geométricos (exterior, envelope e interior) e físicos (calor, ar e umidade). Estes programas podem ser classificados em três principais grupos: programas

The role of the nuclear safety regulator

International Nuclear Information System (INIS)

Mellado, I.

2007-01-01

The Consejo de Seguridad Nuclear (CSN), or Nuclear Safety Council, is the only Spanish institution qualified in nuclear safety and radiological protection. Created in 1980, the CSN is independent of the Central State Administration, and possesses its own legal standing, estate and resources acquired directly from tax revenues. The CSN proposes regulations and advises the government on subjects within its competence, including the criteria for siting nuclear facilities once the autonomous regions have been informed. The CSN is responsible for issuing mandatory and binding reports to the Ministry of Industry. Tourism and Commerce, and for inspections and evaluation of the facilities included within its realm of competence throughout their phases (construction, start-up, operating and decommissioning). It is also responsible for the radiological control and surveillance of workers, the general public and the environment, as described below. In 1999, a new responsibility was assigned to the CSN to perform studies, assessment and inspections in relation to all phases of radioactive waste and spent fuel management. The CSN reports to the Spanish Parliament and is not subject to the hierarchy or auspices of the Government or the organisations in charge of promoting nuclear energy. The Council itself is an Associative Body comprised of 5 members, appointed by Parliament for a 6 year term (these members cannot be removed). Under this Council is situated an extensive technical body. A General Secretary is seconded by Technical Directors in the area of Nuclear Safety and Radiological Protection. As well there are a R and D Office, an Inspection Office, and a Technical Standards Office. The CSN counts 446 workers, of which 191 are university graduate specialists in nuclear safety or radiological protection. The average age is 45 years. Ongoing training is provided in technical specialties and management. (author)

Convex sets in probabilistic normed spaces

International Nuclear Information System (INIS)

Aghajani, Asadollah; Nourouzi, Kourosh

2008-01-01

In this paper we obtain some results on convexity in a probabilistic normed space. We also investigate the concept of CSN-closedness and CSN-compactness in a probabilistic normed space and generalize the corresponding results of normed spaces

Predicción de los precios de contratos de electricidad usando una red neuronal con arquitectura dinámica

Directory of Open Access Journals (Sweden)

Juan David Velásquez Henao

2010-04-01

Full Text Available Los contratos en los mercados liberalizados de electricidad constituyen una herramienta para proteger a los agentes de la volatilidad; en este contexto, los pronósticos de los precios son una entrada clave para la toma de decisiones estratégicas y operativas de los agentes. En este artículo, se pronostican los precios promedios de los contratos despachados en el mercado eléctrico colombiano, usando una red neuronal con arquitectura dinámica conocida como DAN2. El modelo desarrollado es capaz de capturar la dinámica intrínseca de la serie de precios y de pronosticar el precio para el siguiente mes con más precisión que la metodología ARIMA clásica, para horizontes de predicción de 12 y 24 meses

Results of the Interlaboratory Exercise CNS/CIEMAT-2008 among Environmental Radioactivity Laboratories (Phosphogypsum); Evaluacion de la Intercomparacion CSN/CIEMAT-2008 entre Laboratorios Nacionales de Radiactividad Ambiental (Fosfoyeso)

Energy Technology Data Exchange (ETDEWEB)

Romero, M L; Barrera, M; Valino, F

2010-05-27

The document describes the outcome of the CSN/CIEMAT-2008 interlaboratory test comparison among environmental radioactivity laboratories. The exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC. Aphosphogypsum material was used as a test sample, in an attempt to evaluate the performance of the laboratories analyzing NORM (Naturally-Occurring Radioactive Materials). The analysis required were: U-238, Th-234, U-234, Th-230, Ra-226, Pb-214, Bi-214, Pb-210, Po-210, Th-232 and U-235, and also gross alpha and gross beta activities. Reference values have been established according to the method of consensus of expert laboratories, with four international laboratories of credited experience: IAEA Seibersdorf, IAEA MEL, IRSN-Orsay and Sta.Teresa ENEA. The results of the exercise were computed for 34 answering laboratories and their analytical performance was assessed using the z-score. Robust statistics of the participants results was applied to obtain the median and standard deviation, to achieve a more complete and objective study of the laboratories performance. The exercise has shown an homogeneous behaviour of laboratories, being statistical parameters from the results close to the assigned Reference Values. Participant laboratories have demonstrated their ability to determine natural radionuclides in phosphogypsum samples (NORM material) with a satisfactory quality level. The scheme has also allowed examining the capability of laboratories to determine the activities of natural radionuclides at the equilibrium. (Author) 10 refs.

Integrated program of using of Probabilistic Safety Analysis in Spain

International Nuclear Information System (INIS)

1998-01-01

Since 25 June 1986, when the CSN (Nuclear Safety Conseil) approve the Integrated Program of Probabilistic Safety Analysis, this program has articulated the main activities of CSN. This document summarize the activities developed during these years and reviews the Integrated programme

Criptosporidiose em paciente com espondilite anquilosante usando adalimumabe Cryptosporidiosis in a patient with ankylosing spondylitis treated with adalimumab

Directory of Open Access Journals (Sweden)

Fernando Augusto Chiuchetta

2010-06-01

Full Text Available A criptosporidiose é uma doença parasitária causada pelo protozoário Cryptosporidium sp. Observou-se um aumento no número de diagnósticos realizados nos últimos vinte anos, principalmente em pacientes que apresentam imunodeficiências como a síndrome da imunodeficiência humana adquirida e as imunodeficiências induzidas como em pacientes transplantados e nos que necessitam realizar hemodiálise frequentemente. Relata-se o caso de um jovem com espondilite anquilosante que, usando adalimumabe, apresentou diarreia devido à criptosporidiose.Cryptosporidiosis is a parasitic disease caused by a protozoan called Cryptosporidium sp. An increased number of diagnoses were made in the last 20 years, especially in patients with immunodeficiency like the acquired human immunodeficiency syndrome and induced immunodeficiency, such as in transplant patients and those who need frequent hemodialysis, has been observed. We report the case of a young patient with ankylosing spondylitis treated with adalimumab who developed chronic diarrhea secondary to cryptosporidiosis

Results of the Interlaboratory Exercise CNS/CIEMAT-04 Among Environmental Radioactivity Laboratories (Aqueous Solution); Resultados del Ejercicio Interlaboratorios de Radiactividad Ambiental CSN/CIEMAT-04 (Solucion Acuosa)

Energy Technology Data Exchange (ETDEWEB)

Romero Gonzalez, M. L.; Barrera Izquierdo, M.

2004-07-01

The document describes the outcome of the CSN/CIEMAT-04 interlaboratory test comparison among environmental radioactivity laboratories. The exercise was organised according to the ISO-43 and the ISO/IUPAC/AOAC Harmonised Protocol for the proficiency testing of analytical laboratories. Following the issue of the European Community Drinking Water Directive 98/83/EC concerning the quality of water for human consumption, the last inter-comparison exercise was organised by using a water sample, in an attempt to evaluate the performance of the laboratories analysing the required radioactivity parameters (H-3, gross alpha and beta activity and residual beta). The sample (a synthetic drinking water), was prepared at the National Laboratory for Ionising Radiation's Standards (CIEMAT), and contained the following radionuclides ''241 Am, ''239+240 Pu, ''90Sr, ''137 Cs, ''3 H y ''40 K. The results of the exercise were computed for 38 participating laboratories, and their analytical performance was assessed using the z-score approach. Robust statistics of the participant's results was applied to obtain the median and standard deviation, including suspected outliers. The exercise has revealed and homogeneous behaviour of laboratories, being statistical parameters from the results close to the reference values. A raised percentage os satisfactory laboratory performance has been obtained for gross alpha, gross beta and residual beta: 85, 97 and 87% respectively. The study has shown that participant laboratories perform radioactive determinations in drinking water samples with satisfactory quality levels. (Author) 16 refs.

Medición de microdeformaciones en losas viales usando sensores de redes de Braggen fibras ópticas Microdeformation measurement of concrete roadway slabs using fiber Bragg gratings

Directory of Open Access Journals (Sweden)

Francisco Javier Vélez Hoyos

2010-06-01

Full Text Available En este trabajo se presenta un método no invasivo para la medición de microdeformaciones en estructuras de concreto usando sensores de redes de Bragg en fibras ópticas adheridos a su superficie. Se realizan mediciones en losas viales de concreto bajo una carga estática de 10 kN, encontrándose una relación aproximada de 2 : 1 entre la deformación registrada por los sensores y los valores arrojados por una simulación computacional con el método de elementos finitos. Se propone el uso de estos sensores para el monitoreo estructural de losas en una malla vial con sensores distribuidos y multiplexados por longitud de onda. Este es el primer reporte en Colombia de medición de deformación de losas viales usando sensores de fibra óptica.This work shows a non–invasive method for micro–deformation measurements of concrete structures using Bragg grating sensors in optical fibers adhered to the surface. Measurements on roadway slabs under a 10 kN static load are made, finding an approximated ratio of 2 : 1 between the deformation registered by the sensors and the values from a computational simulation with the finite element method. We propose the use of these sensors for slab structural monitoring in a road network employing distributed and wavelength multiplexed sensors. This is a first report in Colombia of roadway slabs microdeformation measurement using fiber optic sensors.

Rapid Screening for Cognitive Impairment in Parkinson’s Disease: A Pilot Study

Directory of Open Access Journals (Sweden)

YanHong Dong

2015-01-01

Full Text Available Aim. This study sought to establish the discriminant validity of a rapid cognitive screen, that is, the National Institute of Neurological Disease and Stroke-Canadian Stroke Network (NINDS-CSN 5-minute protocol, and compare its discriminant validity to the Montreal Cognitive Assessment (MoCA and Mini Mental State Examination (MMSE in detecting cognitive impairment (CI in PD patients. Methods. One hundred and one PD patients were recruited from a movement disorders clinic in Singapore and they received the NINDS-CSN 5-minute protocol, MoCA, and MMSE. No cognitive impairment (NCI was defined as Clinical Dementia Rating (CDR = 0 and CI was defined as CDR ≥ 0.5. Results. Area under the receiver operating characteristic curve of NINDS-CSN 5-minute protocol was statistically equivalent to MoCA and larger than MMSE (0.86 versus 0.90, P=0.07; 0.86 versus 0.76, P=0.03. The sensitivity of NINDS-CSN 5-minute protocol (<9 was statistically equivalent to MoCA (<22 (0.77 versus 0.85, P=0.13 and superior to MMSE (<24 (0.77 versus 0.52, P<0.01 in detecting CI, while the specificity of NINDS-CSN 5-minute protocol (<9 was statistically equivalent to MoCA (<22 and MMSE (<24 (0.78 versus 0.88, P=0.34. Conclusion. The NINDS-CSN 5-minute protocol is time expeditious while remaining statistically equivalent to MoCA and superior to MMSE and therefore is suitable for rapid cognitive screening of CI in PD patients.

Definición de los sectores económicos intensivos en conocimiento a partir de la clasificación que hace la OCDE y el análisis del nivel de cualificación de los trabajadores: análisis para Catalunya

OpenAIRE

Chica Mejía, Juan Eduardo

2011-01-01

Definición de los sectores económicos intensivos en conocimiento a partir de la clasificación que hace la OCDE y el análisis del nivel de cualificación de los trabajadores. Análisis para Catalunya

OTIMIZAÇÃO USANDO ALGORITMO GENÉTICO DE UM MODELO DE PROPAGÇÃO BASEADO EM EQUAÇÕES PARABÓLICAS

Directory of Open Access Journals (Sweden)

Antonio Carlos Vilanova

2013-01-01

Full Text Available Este artigo apresenta uma avaliação metodológica para otimizar parâmetros em um conhecido modelo de propagação de ondas de rádio na troposfera. O modelo de propagação é baseado no Divisor de passos de Fourier para resolver equações parabólicas. Nossa abordagem utiliza algoritmo genético para determinar os valores dos parâmetros que maximize a intensidade de campo em uma determinada posição do observador. Usando algoritmo genético o tempo necessário na busca dos parâmetros ótimos é reduzido significativamente. A avaliação preliminar dos resultados através da simulação mostra que a nossa abordagem é promissora.

Predicción de la generación interna volumétrica de calor y la capacidad calorífica durante un tratamiento electromagnético del material usando algoritmos híbridos

Directory of Open Access Journals (Sweden)

Edgar García-Morantes

2018-01-01

Full Text Available Este trabajo considera la estimación de la generación interna volumétrica de calor y la capacidad calorífica de una muestra esférica sólida calentada por un campo electromagnético homogéneo variante en el tiempo. Para tal fin, la estrategia numérica soluciona el correspondiente problema inverso. Tres formas funcionales (lineal, senoidal y exponencial para el campo electromagnético fueron considerados. Ruido blanco fue agregado al perfil de temperatura teórica (i.e. la solución del problema directo para simular una situación más realística. La temperatura se pretendió que fuera leída por cuatro sensores. El problema inverso fue solucionado a través de tres diferentes enfoques: usando un optimizador tradicional, usando técnicas modernas y usando una mezcla de ambos. En el primer caso, usamos un algoritmo determinístico tradicional como lo es el de Levenberg-Marquardt (LM. En el segundo, consideramos tres metaheurísticos estocásticos: El Algoritmo de optimización de la espiral (SOA, la Búsqueda en vórtice (VS, y el método de atracción ponderada (WAM. Para el caso final, proponemos híbridos entre el LM y los algoritmos metahehurísticos. Los resultados muestran que LM converge a la solución esperada solo si las condiciones iniciales (IC están dentro de un rango limitado. Por otra parte, los metaheurísticos convergen en un amplio rango de IC pero muestra baja precisión. Los enfoques híbridos convergen y mejoran la precisión obtenida con los metaheurísticos. La diferencia entre los valores esperados y obtenidos, así como, los errores RMS son reportados y comparados para los tres métodos.

Avaliação da capacidade resistente última de estacas em compressão usando análises em tensão/deformação

OpenAIRE

Vieira, Ana Rita Ribeiro

2013-01-01

Dissertação para obtenção do Grau de Mestre em Engenharia Civil - Ramo de Estruturas e Geotecnia Nesta dissertação avalia-se a capacidade resistente última de estacas em compressão usando análises em tensão/deformação. A capacidade resistente última das estacas é avaliada através do programa computacional de elementos finitos Plaxis 2D v. 8 e é comparada com a capacidade resistente última prevista por métodos de extrapolação da curva carga vs. assetamento de ensaios de carga que não ...

IDENTIFICACIÓN EFICIENTE DE ERRORES EN ESTIMACIÓN DE ESTADO USANDO UN ALGORITMO GENÉTICO ESPECIALIZADO IDENTIFICAÇÃO EFICAZ DOS ERROS EM ESTIMATIVA DE ESTADO USANDO UM ALGORITMO GENÉTICO ESPECIALIZADO EFFICIENT IDENTIFICATION OF ERRORS IN STATE ESTIMATION THROUGH A SPECIALIZED GENETIC ALGORITHM

Directory of Open Access Journals (Sweden)

Hugo Andrés Ruiz

2012-06-01

Full Text Available En este artículo se presenta un método para resolver el problema de estimación de estado en sistemas eléctricos usando optimización combinatoria. Su objetivo es el estudio de mediciones con errores de difícil detección, que afectan el desempeño y calidad de los resultados cuando se emplea un estimador de estado clásico. Dada su complejidad matemática, se deducen indicadores de sensibilidad de la teoría de puntos de apalancamiento que se usan en el algoritmo de optimización de Chu-Beasley, con el fin de disminuir el esfuerzo computacional y mejorar la calidad de los resultados. El método propuesto se valida en un sistema IEEE de 30 nodos.Neste artigo apresenta-se um método para resolver o problema de estimativa de estado em sistemas elétricos usando otimização combinatória. Seu objetivo é o estudo de medidas com erros de difícil detecção, que afetam o desempenho e qualidade dos resultados quando se emprega um estimador de estado clássico. Dada sua complexidade matemática, deduzem-se indicadores de sensibilidade da teoria de pontos de alavancagem que se usam no algoritmo de otimização de Chu-Beasley, com o fim de diminuir o esforço computacional e melhorar a qualidade dos resultados. O método proposto se valida em um sistema IEEE de 30 nós.In this paper a method to solve the state estimation problem in electric systems applying combinatorial optimization is presented. Its objective is the study of measures with difficult detection errors, which affect the performance and quality of the results when a classic state estimator is used. Due to the mathematical complexity, sensibility indicators are deduced from the theory of leverage points used in the Chu-Beasley optimization algorithm with the purpose of reducing the computational effort and enhance the quality of the results. The proposed method is validated in a 30-node IEEE system.

Producción de Bioetanol a partir de Elodea sp.

Directory of Open Access Journals (Sweden)

Tatiana Marulanda López

2017-02-01

Full Text Available La dependencia de los países a los combustibles fósiles es cada vez mayor, pero estos no son renovables. Además, el uso de estos combustibles ha aumentado la emisión de gases de efecto invernadero. Colombia debe empezar a buscar otras alternativas que suplan la deficiencia en combustible, y cuya fuente de obtención sea renovable y no comprometa los recursos agrícolas usados como alimentos, tal es el caso de la caña de azúcar. Las plantas invasoras se caracterizan por producir eutrofización de las aguas, ocasionando problemas ambientales y de abastecimiento de agua a las ciudades. El manejo que se hace de esta planta es erradicarla usando diferentes métodos. En este artículo se muestra el aprovechamiento de la planta invasora de cuerpos acuosos, Elodea sp., para la obtención de bioetanol. Después de la hidrólisis de los carbohidratos, la detoxificación, y la fermentación, la planta mostró un alto rendimiento en la producción de bioetanol. Este trabajo es la base para el desarrollo del bioproceso, usando como sustrato el material lignocelulítico, y además, es una alternativa para el manejo de la planta Elodea sp. bomo fuente de energía carburante.

Signal compression in radar using FPGA

Directory of Open Access Journals (Sweden)

Enrique Escamilla Hemández

2010-01-01

Full Text Available El presente artículo muestra la puesta en práctica de hardware para realizar el procesamiento en tiempo real de la señal de radar usando una técnica simple, rápida basada en arquitectura de FPGA (Field Programmable Gate Array. El proceso incluye diversos procedimientos de enventanado durante la compresión del pulso del radar de apertura sintética (SAR. El proceso de compresión de la señal de radar se hace con un filtro acoplado. que aplica funciones clásicas y nuevas de enventanado, donde nos centramos en obtener una mejor atenuación para los valores de lóbulos laterales. La arquitectura propuesta explota los recursos de computación paralela de los dispositivos FPGA para alcanzar una mejor velocidad de cómputo. Las investigaciones experimentales han demostrado que los mejores resultados para el funcionamiento de la compresión del pulso se han obtenido usando las funciones atómicas, mejorando el funcionamiento del sistema del radar en presencia de ruido, y consiguiendo una pequeña degradación en la resolución de rango. La puesta en práctica del tratamiento de señales en el sistema de radar en tiempo real se discute y se justifica la eficiencia de la arquitectura de hardware propuesta.

Estimate of DMFT index using teeth most affected by dental caries in twelve-year-old children Estimación del índice DMFT usando los dientes más afectados por caries dentales en niños de doce años Estimativa do Índice CPOD usando os dentes mais afetados pela cárie dentária aos doze anos

Directory of Open Access Journals (Sweden)

Stela Márcia Pereira

2009-02-01

Full Text Available The objective of the study was to develop regression models to describe the epidemiological profile of dental caries in 12-year-old children in an area of low prevalence of caries. Two distinct random probabilistic samples of schoolchildren (n=1,763 attending public and private schools in Piracicaba, Southeastern Brazil, were studied. Regression models were estimated as a function of the most affected teeth using data collected in 2005 and were validated using a 2001 database. The mean (SD DMFT index was 1.7 (2.08 in 2001 and the regression equations estimated a DMFT index of 1.67 (1.98, which corresponds to 98.2% of the DMFT index in 2001. The study provided detailed data on the caries profile in 12-year-old children by using an updated analytical approach. Regression models can be an accurate and feasible method that can provide valuable information for the planning and evaluation of oral health services.El objetivo de este estudio fue desarrollar modelos de regresión para describir el perfil epidemiológico de caries dentales en niños de 12 años en un área de baja prevalencia de caries. Fueron estudiados dos muestras distintas aleatorias y probabilísticas de niños escolares (n= 1.763 que estudiaban en colegios públicos y privados en Piracicaba, Sureste de Brasil. Modelos de regresión fueron estimados como una función de los dientes más afectados usando datos colectados en 2005 y fueron validados usando una base de datos del 2001. El índice promedio (SD de DMFT fue 1,7 (2,08 en 2001 y las ecuaciones de regresión estimaron un índice de DMFT de 1,67 (1,98, lo cual corresponde a 98,2% del índice en 2001. El estudio provee datos detallados sobre el perfil de caries en niños de 12 años usando una aproximación analítica. Los modelos de regresión pueden ser un método confiable y factible que puede proporcional información valiosa para la planificación y evaluación de servicios de cuidado oral.O objetivo do estudo foi

Diseño e implementación de una herramienta para analizar imágenes extraídas de redes sociales, usando la librería OpenCV

OpenAIRE

Ramos Alférez, Albert

2015-01-01

Diseño de una aplicación web que permite extraer información de redes sociales e internet para reconocimiento de personas desaparecidas Design and implementation of a tool for analyzing images taken from social networks, using the OpenCV library Diseño e implementación de una herramienta para analizar imágenes extraídas de redes sociales, usando la librería OpenCV Disseny e implementació d'una eina per analitzar imatges extretes de les xarxes socials, utilitzant la llibrería OpenCV...

CNN's evaluation of the radiological monitoring special programs at the sites of nuclear installations

International Nuclear Information System (INIS)

Lareyne, O.; Marugan Tovar, I.; Martinez Moreno, M.; Sanz Alduan, M. T.

2011-01-01

In 2008, occurred in the Spanish plants various events related to the existence on the sites of the Spanish nuclear facilities or areas dotted with radioactive contamination outside the buildings, events that were reported to the Nuclear Safety Council (CSN) in accordance with the provisions of the regulation, as a result of the analysis of those events, the CSN issued in July 2008, a complementary technique INSTRUCTIONAL requiring the implementation of environmental monitoring programs in outdoor areas within sites nuclear tacilities. First, the CSN nuclear facilities referred to the programs and methodologies intended to perform such monitoring, and, in late 2009, reports of program results.

Medición de microdeformaciones en losas viales usando sensores de redes de Braggen fibras ópticas Microdeformation measurement of concrete roadway slabs using fiber Bragg gratings

OpenAIRE

Francisco Javier Vélez Hoyos; Claudia Milena Serpa Imbet; Nelson Darío Gómez Cardona

2010-01-01

En este trabajo se presenta un método no invasivo para la medición de microdeformaciones en estructuras de concreto usando sensores de redes de Bragg en fibras ópticas adheridos a su superficie. Se realizan mediciones en losas viales de concreto bajo una carga estática de 10 kN, encontrándose una relación aproximada de 2 : 1 entre la deformación registrada por los sensores y los valores arrojados por una simulación computacional con el método de elementos finitos. Se propone el uso de estos s...

Monitoreo de cambios en la densidad de cobertura forestal en bosque templado usando fotografías aéreas digitales de alta resolución

Directory of Open Access Journals (Sweden)

José López García

2016-08-01

Full Text Available Se utilizaron series multitemporales de fotografías aéreas digitales de alta resolución de pequeño formato para evaluar los cambios en la densidad de cobertura forestal en un bosque templado. Una combinación de técnicas convencionales y adaptadas de fotogrametría y fotointerpretación fueron utilizadas para establecer un método específico de evaluación.  Este método ha sido probado en un periodo de doce años (1999-2011 en la zona núcleo de la Reserva de la Biósfera Mariposa Monarca, localizada en los estados de México y Michoacán, en México, usando mosaicos ortorectificados como mapas base para evaluar cambios bienales. Las imágenes fueron fotointerpretadas de manera tradicional marcando los cambios sobre acetatos, colocados sobre las imágenes impresas, creando así nuevos polígonos. Estos fueron transferidos directamente de los acetatos al ortomosaico a través de la pantalla de la computadora, usando al menos tres puntos de control, cumpliendo así con el principio de triangulación radial. El bosque fue separado en las siguientes clases de cobertura forestal: cerrada, semi-cerrada, semi-abierta, abierta y deforestada. La evaluación en la exactitud en la clasificación de densidad de cobertura fue estimada a través de muestreos en campo, empleando matrices de confusión, siendo del 95%. A partir de 2003, este método ha sido utilizado para determinar el pago por servicios ambientales. Dicho pago, junto con una gran interacción con las comunidades, se ha traducido en una reducción en la degradación forestal y la deforestación en la zona núcleo de la Reserva.

APROXIMACIÓN AL ANÁLISIS DE LA VALORACIÓN DE LA PRUEBA USANDO MODIFIED WIGMOREAN ANALYSIS (MWA

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Carlos del Valle Rojas

2009-01-01

Full Text Available El presente trabajo muestra cómo el análisis de la valoración de la prueba, usando herramientas de diagramación argumental, puede ayudar a los operadores jurídicos a evaluar la calidad de la argumentación del razonamiento jurídico. Se aplica el Modified Wigmorean Analysis (MWA a un caso penal hipotético y a un caso real, ensayando el proceso de análisis y diagramación y probando su utilidad. La conclusión reseña las ventajas y debilidades del análisis y sugiere ajustes al proceso de diagramación.The present work shows how the analysis of the valuation of the proof, using tools of plot diagramming, can help the juridical operators to evaluate the quality of the argumentation of the juridical reasoning. There is applied the Modified Wigmorean Analysis (MWA to a penal hypothetical case and to a real case, testing the process of analysis and diagramming and proving his utility. The conclusion outlines the advantages and weaknesses of the analysis and suggests adjustments to the process of diagramming.

Pirólise catalítica do PEBD usando como catalisador a vermiculita modificada

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Franciel Aureliano Bezerra

2016-01-01

Full Text Available Resumo O polietileno de baixa densidade (PEBD é um dos polímeros mais usados atualmente, e a grande quantidade desse polímero produzida resulta em toneladas de resíduos, que necessitam ser tratados. Neste trabalho foi realizada a pirólise termocatalítica do PEBD usando como catalisador a argila vermiculita modificada, como alternativa para o tratamento dos resíduos. A argila foi tratada com solução de ácido nítrico a diferentes concentrações e calcinada a 400 °C. Os materiais foram caracterizados por técnicas de difratometria de raios X, termogravimetria, adsorção de nitrogênio e espectroscopia de energia dispersiva. A pirólise térmica e termocatalítica foi realizada em um micro reator acoplado com GC/MS, a 500 °C. O intuito da pirólise de resíduos poliméricos é a obtenção de hidrocarbonetos leves (C<16, que possam ser empregados na indústria química e petroquímica, através de quebras na cadeia polimérica. Os resultados foram satisfatórios, com aumento no rendimento para hidrocarbonetos leves ao empregar os catalisadores chegando a 71,4% de produtos com C<16, enquanto a pirólise térmica resultou apenas de 25,8%.

Alpha S1-casein polymorphisms in camel (Camelus dromedarius) and descriptions of biological active peptides and allergenic epitopes.

Science.gov (United States)

Erhardt, Georg; Shuiep, El Tahir Salih; Lisson, Maria; Weimann, Christina; Wang, Zhaoxin; El Zubeir, Ibtisam El Yas Mohamed; Pauciullo, Alfredo

2016-06-01

Milk samples of 193 camels (Camelus dromedarius) from different regions of Sudan were screened for casein variability by isoelectric focusing. Kappa-casein and beta-casein were monomorphic, whereas three protein patterns named αs1-casein A, C, and D were identified. The major allele A revealed frequencies of 0.79 (Lahaoi), 0.75 (Shanbali), 0.90 (Arabi Khali), and 0.88 (Arabi Gharbawi) in the different ecotypes. CSN1S1*C shows a single G > T nucleotide substitution in the exon 5, leading to a non-synonymous amino acid exchange (p.Glu30 > Asp30) in comparison to CSN1S1*A and D. At cDNA level, no further single nucleotide polymorphisms could be identified in CSN1S1* A, C, and D, whereas the variants CSN1S1*A and CSN1S1*C are characterized by missing of exon 18 compared to the already described CSN1S1*B, as consequence of DNA insertion of 11 bp at intron 17 which alter the pre-mRNA spliceosome machinery. A polymerase chain-restriction fragment length polymorphism method (PCR-RFLP) was established to type for G > T nucleotide substitution at genomic DNA level. The occurrence and differences of IgE-binding epitopes and bioactive peptides between αs1-casein A, C, and D after digestion were analyzed in silico. The amino acid substitutions and deletion affected the arising peptide pattern and thus modifications between IgE-binding epitopes and bioactive peptides of the variants were found. The allergenic potential of these different peptides will be investigated by microarray immunoassay using sera from milk-sensitized individuals, as it was already demonstrated for bovine αs1-casein variants.

Joint Resource Optimization for Cognitive Sensor Networks with SWIPT-Enabled Relay.

Science.gov (United States)

Lu, Weidang; Lin, Yuanrong; Peng, Hong; Nan, Tian; Liu, Xin

2017-09-13

Energy-constrained wireless networks, such as wireless sensor networks (WSNs), are usually powered by fixed energy supplies (e.g., batteries), which limits the operation time of networks. Simultaneous wireless information and power transfer (SWIPT) is a promising technique to prolong the lifetime of energy-constrained wireless networks. This paper investigates the performance of an underlay cognitive sensor network (CSN) with SWIPT-enabled relay node. In the CSN, the amplify-and-forward (AF) relay sensor node harvests energy from the ambient radio-frequency (RF) signals using power splitting-based relaying (PSR) protocol. Then, it helps forward the signal of source sensor node (SSN) to the destination sensor node (DSN) by using the harvested energy. We study the joint resource optimization including the transmit power and power splitting ratio to maximize CSN's achievable rate with the constraint that the interference caused by the CSN to the primary users (PUs) is within the permissible threshold. Simulation results show that the performance of our proposed joint resource optimization can be significantly improved.

Genetic variability of the equine casein genes.

Science.gov (United States)

Brinkmann, J; Jagannathan, V; Drögemüller, C; Rieder, S; Leeb, T; Thaller, G; Tetens, J

2016-07-01

The casein genes are known to be highly variable in typical dairy species, such as cattle and goat, but the knowledge about equine casein genes is limited. Nevertheless, mare milk production and consumption is gaining importance because of its high nutritive value, use in naturopathy, and hypoallergenic properties with respect to cow milk protein allergies. In the current study, the open reading frames of the 4 casein genes CSN1S1 (αS1-casein), CSN2 (β-casein), CSN1S2 (αS2-casein), and CSN3 (κ-casein) were resequenced in 253 horses of 14 breeds. The analysis revealed 21 nonsynonymous nucleotide exchanges, as well as 11 synonymous nucleotide exchanges, leading to a total of 31 putative protein isoforms predicted at the DNA level, 26 of which considered novel. Although the majority of the alleles need to be confirmed at the transcript and protein level, a preliminary nomenclature was established for the equine casein alleles. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

MODELAMIENTO DE LA CINÉTICA DE BIOADSORCIÓN DE Cr (III USANDO CÁSCARA DE NARANJA

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MARTHA LUCIA PINZÓN-BEDOYA

2009-01-01

Full Text Available En este trabajo se utilizó como material bioadsorbente cáscara naranja con el fin de remover iones cromo presentes en soluciones hipotéticas diluidas, utilizadas como modelo de aguas contaminadas con bajas concentraciones de este metal. Las condiciones de operación utilizadas fueron: relación sólido/líquido 4 g/l, tamaño de partícula ??0,425 mm, concentración inicial de disolución de Cr(III 100 mg/l, tiempo de contacto 60 h y pH constante (4 y 5. Los modelos cinéticos escogidos para identificar el mecanismo de reacción del proceso de bioadsorción usando cáscara de naranja fueron: primer orden reversible, pseudo- segundoorden, Elovich y difusión intraparticular. Los resultados indican que la ecuación de Elovich proporciona mayor exactitud en el ajuste de los datos experimentales del equilibrio a este modelo cinético. La bondad del ajuste de los datos se realizó por regresión no-lineal utilizando como criterio la minimización de la función objeto suma de los cuadrados del error, SCE, haciendo uso de la herramienta matemática MATLAB.

Un estudio sobre el desarrollo del pensamiento aleatorio usando recursos educativos abiertos

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Yenny Patricia Pinzón Triana

2015-04-01

Full Text Available Este estudio presenta los resultados de un proyecto de investigación sobre la implementación de la enseñanza probabilística con recursos educativos abiertos (REA, diseñados en la plataforma Edmodo, y que está dirigido a estudiantes de tercer grado de educación básica secundaria de Bogotá, Colombia, y Tuxtepec, México. El fin era evidenciar sus preconceptos, nociones y evaluar el resultado de la instrucción en términos de su pensamiento probabilístico y dar respuesta a la interrogante ¿cuál es el efecto de la instrucción en probabilidad usando Edmodo en estudiantes de tercer grado de educación básica secundaria respecto a la valoración de fenómenos aleatorios de la vida cotidiana, sus conjeturas y la toma de decisiones? Se empleó un enfoque cualitativo a partir del método de estudio de casos, desde el análisis particular a lo general (Stake, 2005. Para la implementación, se consideró el estudio de Fishbein (1975 sobre el desarrollo del pensamiento probabilístico y el de Marzano (2000, relacionado con las dimensiones del aprendizaje. Estos elementos sirvieron para establecer el impacto del uso de los REA, en especial el de la plataforma Edmodo en el desarrollo de competencias en los estudiantes. Los instrumentos consistieron en una prueba de entrada, actividades de apoyo interactivo desde Edmodo y una prueba de salida para determinar los niveles de aprendizaje; mediante triangulación de datos, se evidenciaron alcances de niveles adecuados de desempeño acordes con los requerimientos de los estándares nacionales e internacionales.

III Technical meeting of CAMP-ESPANA, Madrid 11 november 1999

International Nuclear Information System (INIS)

Veci Marrodan, I.; Lopez Jimenez, J.

2000-01-01

The program CAMP is leading by the Spanish Nuclear Safety Conseil (CSN). The program analyzes the validation and maintenance of thermohydraulic computer codes for the dynamic analysis of NNPPS. The Spanish participation are performed by; CSN, Almaraz, Asco, Cofrentes, Garona, Trillo, Vandellos and Jose Cabrera NNPPS, Universities and engineering companies: ENUSA, Tecnatom, CIEMAT, Empresarios Agrupados, UPV, UPC, UC, UPM

Calculo y comparacion de la prima de un reaseguro de salud usando el modelo de opciones de Black-Scholes y el modelo actuarial

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Luis Eduardo Giron

2015-12-01

Full Text Available La presente investigación pretende calcular y comparar la prima de un reaseguro  usando el modelo de opciones de Black-Scholes y el modelo clásico actuarial tradicional. El período de análisis va desde enero de 2011 hasta diciembre de 2012. Los resultados obtenidos muestran que el modelo de Black-Scholes, que se utiliza normalmente para valorar opciones financieras, puede ser también usado para la estimación de primas de reaseguros de salud; y que la prima neta estimada a partir de este modelo se aproxima a las establecidas por el método actuarial, excepto cuando el deducible del reaseguro es muy alto (por encima de $200.000.000.

Una herramienta para la automatización de procesos de desarrollo de software usando QVT: transformación de controles de flujo SPEM a BPMN

OpenAIRE

Zorzán, Fabio Andrés; Daniele, Marcela; Frutos, Mariana; Uva, Marcelo

2014-01-01

Desde hace unos años Query/Views/Transformations (QVT), definido por la Object Management Group (OMG), se ha convertido en una herramienta muy utilizada a la hora de definir transformaciones de modelos. Este trabajo propone una herramienta QVT que permite la transformación de modelos que representan procesos de desarrollo de software, basados en el Software Process Engineering Metamodel versión 2 (SPEM), hacia modelos de procesos genéricos basados en la notación Business Process Modeling Nota...

Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells

International Nuclear Information System (INIS)

Füllbeck, Melanie; Huang, Xiaohua; Dumdey, Renate; Frommel, Cornelius; Dubiel, Wolfgang; Preissner, Robert

2005-01-01

Inhibition of the COP9 signalosome (CSN) associated kinases CK2 and PKD by curcumin causes stabilization of the tumor suppressor p53. It has been shown that curcumin induces tumor cell death and apoptosis. Curcumin and emodin block the CSN-directed c-Jun signaling pathway, which results in diminished c-Jun steady state levels in HeLa cells. The aim of this work was to search for new CSN kinase inhibitors analogue to curcumin and emodin by means of an in silico screening method. Here we present a novel method to identify efficient inhibitors of CSN-associated kinases. Using curcumin and emodin as lead structures an in silico screening with our in-house database containing more than 10 6 structures was carried out. Thirty-five compounds were identified and further evaluated by the Lipinski's rule-of-five. Two groups of compounds can be clearly discriminated according to their structures: the curcumin-group and the emodin-group. The compounds were evaluated in in vitro kinase assays and in cell culture experiments. The data revealed 3 compounds of the curcumin-group (e.g. piceatannol) and 4 of the emodin-group (e.g. anthrachinone) as potent inhibitors of CSN-associated kinases. Identified agents increased p53 levels and induced apoptosis in tumor cells as determined by annexin V-FITC binding, DNA fragmentation and caspase activity assays. Our data demonstrate that the new in silico screening method is highly efficient for identifying potential anti-tumor drugs

Maximización de la función de Verosimilitud de Distribuciones de Probabilidad usando Algoritmos Genéticos

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Oscar Arturo Fuentes Mariles

2015-01-01

Full Text Available Tradicionalmente, para obtener los parámetros de una función de distribución con el método de máxima verosimilitud se acostumbra igualar a cero la derivada del logaritmo de la función de verosimilitud y resolver el sistema de ecuaciones no lineales que resulta. La popularidad del procedimiento se debe a su sencillez; sin embargo, cuando la función de verosimilitud no es suficientemente regular, puede llevar a obtener un valor muy alejado del máximo Por ese motivo, en este documento se presenta el uso de un algoritmo genético que permite encontrar los parámetros de la función de distribución (con los que se maximiza directamente la función de verosimilitud, o su logaritmo, sin recurrir a la derivada de los logaritmos de dicha función. Se halló buena concordancia de los resultados respecto a los obtenidos usando un software de uso frecuente en México, para el caso las funciones Gumbel y Gumbel de dos poblaciones. 

Assessment of RELAP5/MOD2 against a main feedwater turbopump trip transient in the Vandellos II Nuclear Power Plant

International Nuclear Information System (INIS)

Llopis, C.; Casals, A.; Perez, J.; Mendizabal, R.

1993-12-01

The Consejo de Seguridad Nuclear (CSN) and the Asociacion Nuclear Vandellos (ANV) have developed a model of Vandellos II Nuclear Power Plant. The ANV collaboration consisted in the supply of design and actual data, the cooperation in the simulation of the control systems and other model components, as well as in the results analysis. The obtained model has been assessed against the following transients occurred in plant: A trip from the 100% power level (CSN); a load rejection from 100% to 50% (CSN); a load rejection from 75% to 65% (ANV); and, a feedwater turbopump trip (ANV). This copy is a report of the feedwater turbopump trip transient simulation. This transient actually occurred in the plant on June 19, 1989

Corrigendum

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Carlos Vargas

2012-07-01

Full Text Available Presentamos excusas a nuestros lectores y al antropólogo Javier Andrés Sandoval Andrade puesto que en el Vol 15 No 2 del 2011 de la revista Earth Science research Journal (ESRJ se publicó el articulotitulado "Quaternary dating by electron spin resonance (ESR applied to human tooth enamel" en el cual no se hace un correcto pie de página de la figura 1, ya que no es tomada de (Groot, 1992como reza la misma, sino que es tomada de la tesis de pregrado titulada DATACIÓN DE RESTOS HUMANOS PREHISPÁNICOS A TRAVÉS DE ESMALTE DENTAL USANDO RESONANCIAPARAMAGNÉTICA ELECTRÓNICA (EPR (2010. Asimismo, no corresponde al sitio arqueológico Aguazuque, sino que corresponde al sitio arqueológico Checua. Corrigendum We apologize to our readers and the antropology Javier andres Sandoval Andrade because in the Vol 15 Issue 2 year 2011 in the Earth Science Research Journal (ESRJ published the article entitled "Quaternary dating by electron spin resonance (ESR applied to human tooth enamel" which there is an incorrect footnote in the Figure 1 as it is not quoted from (Groot, 1992, but it is taken from the undergraduate thesis entitled DATACION DE RESTOS HUMANOS PREHISPANICOS A TRAVES DE ESMALTE DENTAL USANDO RESONANCIA PARAMAGNETICA ELECTRONICA (EPR (2010. Also, this figure do not correspond with the Aguazuque arqueological site, but it is from the Checua arquelogical site. Carlos Vargas Editor-in-Chief Earth Science Research Journal

Results of the Interlaboratory Exercise CNS/CIEMAT-05 among Environmental Radioactivity Laboratories (Vegetable Ash); Evaluacion de la Intercomparacion CSN/CIEMAT-2005 entre Laboratorios Nacionales Radiactividad Ambiental (Ceniza Vegetal)

Energy Technology Data Exchange (ETDEWEB)

Romero Gonzalez, M. L.; Barrera Izquierdo, M.; Valino Garcia, F.

2006-07-01

The document describes the outcome of the CSN/CIEMAT-05 interlaboratory test comparison among environmental radioactivity laboratories. The exercise was organised according to the ISO-43 and the IUPAC {sup I}nternational harmonised protocol for the proficiency testing of analytical chemistry laboratories{sup .} The exercise has been designed to evaluate the capability of national laboratories to determine environmental levels of radionuclides in vegetable ash samples. The sample has been prepared by the Environmental Radiation Laboratory, from the University of Barcelona, and it contains the following radionuclides: Sr-90, Pu-238, Am-241, Th-230, Pb-210, U-238, Ra-226, K-40, Ra-228, TI-208, Cs- 137 and Co-60. Reference values have been established TROUGH the kind collaboration of three international laboratories of recognized experience: IAEA MEL and IRSN-Orsay. The results of the exercise were computed for 35 participating laboratories and their analytical performance was assessed using the z-score approach. Robust statistics of the participant's results was applied to obtain the median and standard deviation, to achieve a more complete and objetiva study of the laboratories' performance. Some difficulties encountered to dissolve the test sample caused a lower response of analyses involving radiochemical separation, thus some laboratories couldn't apply their routine methods and no conclusions on PU-238, Am-241 and Th-230 performances have been obtained. The exercise has revealed an homogeneous behaviour of laboratories, being statistical parameters from the results close to the reference values. The study has shown that participant laboratories perform radioactive determinations in vegetable ash samples with satisfactory quality levels. (Author) 6 refs.

Simulación y validación de modelos de destilación por lotes usando Aspen Batch Modeler: recuperación de epóxido de limoneno

OpenAIRE

Yeison Agudelo; Rolando Barrera Zapata

2016-01-01

Se desarrolló el modelado y simulación de una columna de destilación por lotes para la recuperación de epóxido de limoneno de una mezcla multicomponente, usando el software especializado Aspen Batch Modeler. Para la validación de los modelos se desarrolló el proceso experimental en un equipo de roto-evaporación, donde se varió la composición inicial de la mezcla, temperatura y presión de operación. La composición final de fondos y destilado se determinó a través de cromatografía de gases. Los...

JMat - Herramienta remota de cálculo y multiusuario para el aprendizaje basado en problemas usando Matlab

Directory of Open Access Journals (Sweden)

Bladimir Bacca Cortes

2011-01-01

Full Text Available JMat es una herramienta de cálculo basada en JAVA y EJS (Easy Java Simulations, con un esquema cliente / servidor, soporte multi-usuario y acceso remoto a Matlab. La aplicación está orientada a brindar a los usuarios una interacción con Matlab usando tres interfaces: Consola de Comandos, donde se invocan remotamente comandos de texto compatibles con Matlab. Espacio de Trabajo y Graficación, donde se mantiene un registro automático de las variables de usuario y se grafican individualmente. Funciones de usuario y Transferencia de Archivos, donde el usuario crea sus funciones, envía y recibe datos hacia y desde el servidor. JMat requiere un acceso a Internet, un servidor remoto donde esté instalado Matlab y un cliente (Navegador WEB o aplicación. No se requiere Matlab en el cliente. JMat está siendo usada actualmente en la Universidad del Valle en los cursos de Control Automático de Procesos, Control Inteligente, Redes Neuronales Artificiales, Procesamiento de Señales y Tratamiento Digital de Imágenes como herramienta para el aprendizaje basado en problemas empleando la plataforma de eLearning de la Universidad del Valle.

Susceptibilidad dE Lutzomyia verrucarrum a piretroides en zonas endémicas de Enfermedad de Carrión de Ancash

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Jorge Lucero

2008-04-01

Full Text Available La enfermedad de Carrión es una infección metaxénica endémica del Perú, el control vectorial de la Lutzomyia verrucarum con insecticidas es una de las formas más usadas para reducir su morbilidad. Se determinó la susceptibilidad de este vector a los piretroides más usados (cyflutrina, alfacipermetrina y deltametrina en dos zonas endémicas altoandinas de Ancash (Llumpa: 3200 msnm y Maya: 2600 msnm, Perú en junio de 1999. Se expuso a 50 mosquitos por cada zona e insecticida usando la prueba de contacto para anophelinos modificada. Se encontró una mortalidad del 100% para cada piretroide ensayado. Si bien se demostró una susceptibilidad total de L. verrucarum es necesario implementar la vigilancia de la resistencia a insecticidas como se hace con otros vectores en el Perú.

Paralelización del Algoritmo Criptográfico GOST Empleando el Paradigma de Memoria Compartida

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Marlis Fulgueira-Camilo

2015-06-01

Full Text Available El artículo refiere el proceso de paralelización del algoritmo criptográfico GOST. La investigación realizada persigue como objetivo, reducir el tiempo de ejecución del algoritmo. El estudio no se encuentra enfocado al análisis de fortaleza del algoritmo criptográfico, donde se hace énfasis es en el método empleado para disminuir el tiempo de ejecución de los procesos cifre y descifre. Para ello se realiza un diseño paralelo basado en la metodología de Ian Foster, el cual es aplicado a dos implementaciones usando técnicas como: OpenMP y CUDA. Las comparaciones realizadas teniendo en cuenta, tanto al algoritmo secuencial como las implementaciones paralelas, demuestran una significativa reducción de tiempo, sin importar la técnica empleada. El mejor resultado se logra empleando CUDA.

Sensitivity and Specificity of a Five-Minute Cognitive Screening Test in Patients With Heart Failure.

Science.gov (United States)

Cameron, Janette D; Gallagher, Robyn; Pressler, Susan J; McLennan, Skye N; Ski, Chantal F; Tofler, Geoffrey; Thompson, David R

2016-02-01

Cognitive impairment occurs in up to 80% of patients with heart failure (HF). The National Institute for Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network (CSN) recommend a 5-minute cognitive screening protocol that has yet to be psychometrically evaluated in HF populations. The aim of this study was to conduct a secondary analysis of the sensitivity and specificity of the NINDS-CSN brief cognitive screening protocol in HF patients. The Montreal Cognitive Assessment (MoCA) was administered to 221 HF patients. The NINDS-CSN screen comprises 3 MoCA items, with lower scores indicating poorer cognitive function. Receiver operator characteristic (ROC) curves were constructed, determining the sensitivity, specificity and appropriate cutoff scores of the NINDS-CSN screen. In an HF population aged 76 ± 12 years, 136 (62%) were characterized with cognitive impairment (MoCA area under the receiver operating characteristic curve indicated good accuracy in screening for cognitive impairment (0.88; P cognitive impairment in patients with HF. Future studies should include a neuropsychologic battery to more comprehensively examine the diagnostic accuracy of brief cognitive screening protocols. Copyright © 2016 Elsevier Inc. All rights reserved.

Estimate potential evaporation and solar radiation in the Yaqui valley, Sonora, Mexico, using data from satellite; Estimacion de evaporacion y radiacion solar en el valle del Yaqui, Sonora, usando datos de satelite

Energy Technology Data Exchange (ETDEWEB)

J Watts, Christopher; Rodriguez, Julio Cesar [Instituto del Medio Ambiente y el Desarrollo sustentable del estado de Sonora (Mexico); Garatuza Payan, Jaime [Instituto Tecnologico de Sonora (Mexico); Henk de Bruin [Universidad Agricola de Wageningen (Netherlands); Stewart, John [Universidad de Southampton (United Kingdom)

1999-12-01

The data from tow automatic weather stations in the Yaqui valley were used to estimate potential evaporation using the Makkink formula, based on observed incoming solar radiation and climatological values of air temperature. The usefulness of this formula was assessed by comparison with the Penman-Monteith, Penman and Priestley-Taylor formula and measurements of net radiation. A methodology was presented for estimating incoming solar radiation using visible band data from the GOES satellite. Comparisons against ground-based measurements from two pyranometers installed in the Yaqui valley gave good results, particularly in months with low cloud cover. Images for August 1993 were used to produce a map of the spatial distribution of potential evaporation. [Spanish] Para calcular la evaporacion potencial en el valle del Yaqui, usando la formula de Makkink, se utilizaron datos de dos estaciones meteorologicas automaticas. La mencionada formula se basa en la radiacion solar incidente observada y en ciertos valores climatologicos de temperatura del aire. Se evaluo la utilidad de esta formula, comparandola con las de Penman-Monteith, Pennan y Priestley-Taylor, asi como con mediciones de radiacion neta. Se desarrollo una metodologia para estimar la radiacion solar incidente usando la banda visible del satelite GOES. Se hizo una comparacion con mediciones de dos piranometros instalados en el valla del Yaqui, obteniendose buenos resultados, principalmente en meses con poca nubosidad. Se utilizaron imagenes de agosto de 1993 para producir un mapa de la distribucion espacial de la evaporacion potencial.

Desenvolvimento e validação de metodos para a determinação de antimicrobianos em leite e farmacos usando a cromatografia liquida de alta eficiencia e eletroforese capilar

OpenAIRE

Monica Cecilia Vargas Mamani

2007-01-01

Resumo: Antimicrobianos são largamente empregados na medicina veterinária e resíduos destes podem permanecer nos alimentos de origem animal, acima de valores considerados seguros, quando não são respeitadas as boas práticas veterinárias. O objetivo deste trabalho foi o desenvolvimento e validação de métodos para a determinação de tetraciclinas, sulfonamidas, cloranfenicol e fluoroquinolonas em fármacos usando a eletroforese capilar (CE), assim como método multiresíduos para a determinação de ...

Nuclear safety in Spain

International Nuclear Information System (INIS)

Caro, R.

1988-01-01

Control and monitoring of all Spanish nuclear facilities was first carried out by the Department of Nuclear Safety of the Junta de Energia Nuclear established by the Nuclear Energy Act in 1964. Later, following the example of other Western countries, it was concluded that regulations and monitoring of nuclear energy on one hand and its promotion and development on the other should not be done by the same national body. Therefore, the Consejo de Seguridad Nuclear (CSN) was created in 1980, as the sole national body responsible for controlling the safety of nuclear installations, and radiological protection. The CSN has five members, one chairman and four comissioners, required to be independent and therefore with politically objective criteria, internationally acknowledged technical capability, and free from other duties and responsibilities. For this purpose the Chairman has been given the status of Minister and the commissioners that of Secretary of State. They serve for six years, after being accepted by Parliament by a majority of at least 3/5 of the votes, and are called upon to report to Parliament at least twice a year on nuclear safety and radiological protection in the country. A complete report on those issues is presented to Parliament, becoming a politic document as from that moment. To prepare that report (basically a summary of CSN activities) and, in general, to fulfill all its tasks, the CSN has a staff of some 300, about 50% being technical. CSN activities cover: 1. Standards; 2. Licences; 3. Research; 4. Environment; 5. Information; and 6. International Relations

Knowledge and behavior of Nigerian dentists concerning the treatment of children with special needs

Directory of Open Access Journals (Sweden)

Sanu Oluwatosin O

2006-06-01

Full Text Available Abstract Background Children with special needs (CSN are reported to receive less adequate dental care due to various behavioral problems and barriers created by dental professionals. This study was carried out to determine the knowledge and behaviour of Nigerian dentists concerning the treatment of CSN. Methods Questionnaires consisting of open and closed ended questions requesting socio-demographic information, type of practice, undergraduate and postgraduate training, self-rated knowledge and behaviour concerning care of CSN, were hand delivered to 359 dentists in the 3 geographical zones of Nigeria over a period of 8 weeks. Responses were compared across age groups, gender, type of practice and training received. Result Two hundred and eighty questionnaires were returned completed, constituting 79.9% response rate. Most of the respondents were aged 30 – 39 years (44.3%. There were more males (56.1% and more recent graduates of 10 years and below (78.5%. Over 80% of respondents had treated children with disabilities, those with physical disabilities being most encountered. Only 19.3% of respondents rated their knowledge of management of CSN as adequate, with no significant difference across age groups and gender, but with a significantly higher number of older graduates reporting to have adequate knowledge (p Conclusion From this study, very few dentists reported to have adequate knowledge of management of CSN, irrespective of age, gender and place of practice. A significant number of those with more experience rated their knowledge as adequate. Although most dentists rated the children's behaviour as challenging, they indicated their willingness to treat them in their practices.

Results of special monitoring programs at the sites of nuclear facilities: implications for environmental monitoring program (PVRA); Resultados de los programas especiales de vigilancia radiologica en los emplazamientos de las instalaciones nucleares: implicaciones en el programa de vigialncia radiologica ambiental (PVRA)

Energy Technology Data Exchange (ETDEWEB)

Marugan Tovar, I.; Sanz Alduan, M. T.; Luque Heredia, S.; Rey del Castillo, C.; Salas Collantes, R.; Sterling Carmona, A.; Ramos Salvador, L.; Lorente Lorente, P.

2013-07-01

In 2008, they occurred in the Spanish plants various events related to the existence on the sites of points or areas of radioactive contamination on the outside of buildings. The events were reported to the CSN in accordance with the provisions of the Instruction CSN IS-10. This presentation brings together the assessments provided, the result of the checks and the consequences of the programs. (Author)

Estimación de la demanda de agua para uso residencial urbano usando un modelo discreto-continuo y datos desagregados a nivel de hogar: el caso de la ciudad de Manizales, Colombia

OpenAIRE

Darío Jiménez; Sergio Orrego; Felipe Vásquez; Roberto Ponce

2017-01-01

En el presente trabajo se estima la demanda de agua para uso residencial urbano en la ciudad de Manizales, Colombia, usando un modelo estructural que considera tanto la elección discreta del bloque de consumo como la elección continua sobre la cantidad a consumir. La demanda se estimó econométricamente utilizando una base de datos única para un país en desarrollo y que contiene información completa sobre el consumo mensual de agua, el tamaño del hogar, las características de la vivienda, vari...

C60 fullereno modificado por haces de iones de baja energía para prevenir el efecto multipactor

Directory of Open Access Journals (Sweden)

Galán, L.

2005-04-01

Full Text Available C60 fullerene modified by low-energy ion beams of H2 +, N2 +, O2 + y Ar+ has been studied. After ion bombardment, the photoemission spectra obtained using synchrotron radiation show an increase of the density of states just bellow the Fermi level. Ion bombarment of C60 with 50 eV energy and 4×1014 ion/cm2 fluence is sufficient to modify the cage structure of the fullerene and to obtain graphitic amorphous carbon. Upon bombarding with an energy of 50 eV, implantation of the nitrogen and the oxygen ions was observed, while implantation of the hydrogen and argon ions was small. The maximum secondary emission yield of C60 thin films is lower than 1.3 even after air exposure. A significant improvement on the secondary emission properties can be obtained after bombardment by low-energy Ar+ and N2 + ion beams.Se ha estudiado la interacción de los iones H2 +, N2 +, O2 + y Ar+ de baja energía con películas delgadas de fullereno C60. Después del bombardeo iónico, la densidad de estados cerca del nivel de Fermi aumenta de forma apreciable, según se observa en los espectros de fotoemisión obtenidos usando radiación sincrotrón. El bombardeo iónico con una energía de tan sólo 50 eV y una fluencia de 4x1014 ion/cm2 es suficiente para modificar la simétrica estructura de caja del fullereno y obtener carbono amorfo grafítico. El nitrógeno y el oxígeno se implantan al bombardear con una energía de 50 eV, mientras que la implantación es despreciable en el caso del hidrógeno y argon. Las películas de fullereno poseen un coeficiente máximo de emisión secundaria inferior a 1.3 incluso después de su exposición al aire, el cual disminuye después del bombardeo con iones de N2 + y Ar+.

MODELADO DEL PRECIO SPOT DE LA ELECTRICIDAD EN BRASIL USANDO UNA RED NEURONAL AUTORREGRESIVA ELECTRICITY SPOT PRICE MODELLING IN BRASIL USING AN AUTOREGRESSIVE NEURAL NETWORK

Directory of Open Access Journals (Sweden)

Juan D Velásquez

2008-12-01

Full Text Available Una red neuronal autorregresiva es estimada para el precio mensual brasileño de corto plazo de la electricidad, la cual describe mejor la dinámica de los precios que un modelo lineal autorregresivo y que un perceptrón multicapa clásico que usan las mismas entradas y neuronas en la capa oculta. El modelo propuesto es especificado usando un procedimiento estadístico basado en el contraste del radio de verosimilitud. El modelo pasa una batería de pruebas de diagnóstico. El procedimiento de especificación propuesto permite seleccionar el número de unidades en la capa oculta y las entradas a la red neuronal, usando pruebas estadísticas que tienen en cuenta la cantidad de los datos y el ajuste del modelo a la serie de precios. La especificación del modelo final demuestra que el precio para el próximo mes es una función no lineal del precio actual, de la energía afluente actual y de la energía almacenada en el embalse equivalente en el mes actual y dos meses atrás.An autoregressive neural network model is estimated for the monthly Brazilian electricity spot price, which describes the prices dynamics better than a linear autoregressive model and a classical multilayer perceptron using the same input and neurons in the hidden layer. The proposed model is specified using a statistical procedure based on a likelihood ratio test. The model passes a battery of diagnostic tests. The proposed specification procedure allows us to select the number of units in hidden layer and the inputs to the neural network based on statistical tests, taking into account the number of data and the model fitting to the price time series. The final model specification demonstrates that the price for the next month is a nonlinear function of the current price, the current energy inflow, and the energy saved in the equivalent reservoir in the current month and two months ago.

Estudio comparativo de flujo de fluido a través de una placa de orificio usando las ecuaciones de Stokes y de Navier-Stokes

Directory of Open Access Journals (Sweden)

Miryam Lucía Guerra-Mazo

2016-05-01

Full Text Available Presenta los resultados de la comparación entre las ecuaciones de Stokes y de Navier-Stokes para la simulación del flujo de agua líquida, a condiciones atmosféricas, a través de una placa orificio concéntrica. A partir de los datos experimentales que fueron tomados en el banco de fluidos, se evaluaron las simulaciones de ambas ecuaciones, usando el software libre Freefem++cs, que se basa en el método de los elementos finitos; las variables evaluadas son velocidad y presión en un intervalo de tiempo. Al analizar los resultados obtenidos con las simulaciones y comparar con los datos experimentales se encontró que las ecuaciones de Navier-Stokes representan mejor el sistema que la ecuación de Stokes.

Radioinmunoanalisis simultaneo de cinco hormonas esteroidales

Directory of Open Access Journals (Sweden)

Myriam Sanchez de Gomez

2009-07-01

Full Text Available En este trabajo se describe un método para la determinación de androstendiona, progesterona.dihidi'otestosterona, testosterona y 17—hidroxi—progesterona en muestras de 1 ml de suero femenino y masculino. Después de la extracción de los esteroides la mezcla es sometida a cromatografía en una columna de Lipidex—5000 (hidroxialcoxipropil Sephadex en n— hexano: cloroformo 95:5. La evaluación final de los diferentes esteroides se hace por medio de radioinmunoanálisis específicos usando carbón—dextrano [jara separar las fracciones libre y ligada de la radioactividad. Los cinco compuestos se resolvieron en cuatro fracciones eluyendo conjuntamenteandrostendiona y progesterona, las cuales fueron determinadas específicamente usando antisueros selectivos. La recuperación varió entre 63.5 y 93.7% siendo los valores más bajos para dihidrotestosterona. La interferencia o blanco para los cinco esteroides fue inferior al límite de detección de los radioinmunoanálisis (10 pg y la exactitud, usando el criterio de la prueba de pureza radioquímica,fue comprobada para los análisis de progesterona y testosterona. En un estudio comparativo se analizaron las cinco hormonas en un grupo de hombres y mujeres normales mediante la determinación directa del extracto y después de la etapa cromatográfica. En la mayoría de los casos se encontrarondiferencias significativas entre los promedios de uno y otro método y solo en uno de ellos (17—hidroxiprogesterona en suero masculino no hubo diferencia. Se establecieron los niveles de estos esteroides en suero femenino en las fases folicular y luteal del ciclo menstrual y en algunos de ellos se estudió la variación circadiana. Dichos niveles también se determinaron después de practicar pruebasde estímulo y/o de freno para su secreción, en muestras provenientes de pacientes con sospecha de alteración relacionada con el hirsutismo.

Comparación y predicción de las cuotas mundiales de publicación de los EUA, EU-27 y China usando la nueva interfaz Web of science versus Scopus

NARCIS (Netherlands)

Leydesdorff, L.

2012-01-01

La nueva interfaz de la Web of science (de Thomson Reuters) permite ahora recuperar conjuntos de más de 100.000 documentos en una sola búsqueda. Esto hace posible comparar las tendencias de publicación de los EUA, UE-27 y China -y evidentemente también de los países más pequeños-, cosa que ya se

La lectura no utilitaria en la universidad en la era digital. Un análisis multivariante que ubica el texto impreso en la lectura de literatura

Directory of Open Access Journals (Sweden)

A. Olivia Jarvio Fernández

2018-03-01

Full Text Available En este trabajo se explora la preferencia del texto impreso para la lectura de literatura en una comunidad universitaria. Se hace una caracterización de la lectura y la escritura en la universidad y se presenta una revisión de la importancia de la lectura no utilitaria en este contexto. Se revisa el tema de la apropiación de las TIC en el ámbito universitario, identificando la relevancia de la lectura y la escritura en la era digital. El estudio de caso usa datos de una encuesta aplicada en la Universidad Veracruzana, para lo que se presenta el contexto y los antecedentes. Se hace una descripción de las variables y la estrategia de análisis estadístico. Se analizan los factores que están asociados a la preferencia de formato y se caracterizan las principales asociaciones a partir de pruebas de independencia usando el estadístico Ji-Cuadrado; para las asociaciones multivariantes se corrió un análisis de correspondencia múltiple. Se concluye que la preferencia del texto impreso sigue siendo muy marcada, un poco más entre las mujeres, destacándose el nivel de gusto y el tiempo de dedicación entre los académicos y los funcionarios. No obstante, el concepto de lectura que es más frecuente se relaciona con la lectura utilitaria.

A combination of exercise and capsinoid supplementation additively suppresses diet-induced obesity by increasing energy expenditure in mice.

Science.gov (United States)

Ohyama, Kana; Nogusa, Yoshihito; Suzuki, Katsuya; Shinoda, Kosaku; Kajimura, Shingo; Bannai, Makoto

2015-02-15

Exercise effectively prevents the development of obesity and obesity-related diseases such as type 2 diabetes. Capsinoids (CSNs) are capsaicin analogs found in a nonpungent pepper that increase whole body energy expenditure. Although both exercise and CSNs have antiobesity functions, the effectiveness of exercise with CSN supplementation has not yet been investigated. Here, we examined whether the beneficial effects of exercise could be further enhanced by CSN supplementation in mice. Mice were randomly assigned to four groups: 1) high-fat diet (HFD, Control), 2) HFD containing 0.3% CSNs, 3) HFD with voluntary running wheel exercise (Exercise), and 4) HFD containing 0.3% CSNs with voluntary running wheel exercise (Exercise + CSN). After 8 wk of ingestion, blood and tissues were collected and analyzed. Although CSNs significantly suppressed body weight gain under the HFD, CSN supplementation with exercise additively decreased body weight gain and fat accumulation and increased whole body energy expenditure compared with exercise alone. Exercise together with CSN supplementation robustly improved metabolic profiles, including the plasma cholesterol level. Furthermore, this combination significantly prevented diet-induced liver steatosis and decreased the size of adipocyte cells in white adipose tissue. Exercise and CSNs significantly increased cAMP levels and PKA activity in brown adipose tissue (BAT), indicating an increase of lipolysis. Moreover, they significantly activated both the oxidative phosphorylation gene program and fatty acid oxidation in skeletal muscle. These results indicate that CSNs efficiently promote the antiobesity effect of exercise, in part by increasing energy expenditure via the activation of fat oxidation in skeletal muscle and lipolysis in BAT. Copyright © 2015 the American Physiological Society.

Application of leak-before-break to primary loop piping to eliminate pipe whip restraints in a Spanish nuclear power plant

International Nuclear Information System (INIS)

Rodriguez, M.; Esteban, A.

1990-01-01

The Spanish plant described in this study is a 982 MWe PWR with a three-loop primary circuit of piping made from centrifugally-cast stainless steel SA351 CF8A. The licensee requested from Consejo de Seguridad Nuclear (CSN) an exemption from the general design criterion, GDC-4, so as to avoid the need to postulate a guillotine rupture of the primary loop piping. The request was based on the generic work performed for a US PWR plant group in order to have such an exemption. As the piping material in the Spanish plant is different from that in the plants included in the generic work, CSN performed a review of the applicability of the generic results to the Spanish plant. Also, aspects such as fatigue evaluation, net section collapse, crack growth and leak detection, specifically analyzed for the Spanish plant, were reviewed. CSN found that fracture toughness test results from generic work are applicable to the Spanish plant; sufficient margin exists against unstable crack extension, and adequate leak detection capability exists with the leakage detection systems available in the plant. Exemption from GDC-4 was approved and CSN authorized the licensee to remove protection devices against dynamic loads from guillotine breaks in the primary coolant loops. (author)

Effects of Arginine Concentration on the In Vitro Expression of Casein and mTOR Pathway Related Genes in Mammary Epithelial Cells from Dairy Cattle

Science.gov (United States)

Wang, Mengzhi; Xu, Bolin; Wang, Hongrong; Bu, Dengpan; Wang, Jiaqi; Loor, Juan-Jose

2014-01-01

Arginine (Arg) is a conditionally-essential amino acid that is taken up by bovine mammary gland in excess of its output in milk. In this study we evaluated the effects of Arg concentration on the expression of casein and signaling pathway-related genes in mammary epithelial cells. The treatments (applied for 24 h) were designed to be devoid of Arg 0X (control; 0.00 mg/L), resemble the profile of Arg in casein (Arg 1X; 278.00 mg/L), be deficient [Arg 0.25X (69.50 mg/L) and Arg 0.5X (139.00 mg/L)], or be in excess of the amount in casein [Arg 2X (556.00 mg/L), Arg 4X (1,112 mg/L), and Arg 8X (2,224 mg/L)]. The expression of CSN1S, CSN3 and mTOR in the experimental groups was higher than those of the control group (P0.05), the expression of CSN1S2, CSN2 and JAK2 in other experimental groups was higher (P0.05), the expression of STAT5 in the other experimental groups was higher than those of the control (Pcasein genes and mTOR-related genes in bovine mammary epithelial cells. PMID:24788778

Design of chemical space networks using a Tanimoto similarity variant based upon maximum common substructures.

Science.gov (United States)

Zhang, Bijun; Vogt, Martin; Maggiora, Gerald M; Bajorath, Jürgen

2015-10-01

Chemical space networks (CSNs) have recently been introduced as an alternative to other coordinate-free and coordinate-based chemical space representations. In CSNs, nodes represent compounds and edges pairwise similarity relationships. In addition, nodes are annotated with compound property information such as biological activity. CSNs have been applied to view biologically relevant chemical space in comparison to random chemical space samples and found to display well-resolved topologies at low edge density levels. The way in which molecular similarity relationships are assessed is an important determinant of CSN topology. Previous CSN versions were based on numerical similarity functions or the assessment of substructure-based similarity. Herein, we report a new CSN design that is based upon combined numerical and substructure similarity evaluation. This has been facilitated by calculating numerical similarity values on the basis of maximum common substructures (MCSs) of compounds, leading to the introduction of MCS-based CSNs (MCS-CSNs). This CSN design combines advantages of continuous numerical similarity functions with a robust and chemically intuitive substructure-based assessment. Compared to earlier version of CSNs, MCS-CSNs are characterized by a further improved organization of local compound communities as exemplified by the delineation of drug-like subspaces in regions of biologically relevant chemical space.

Enhanced oil recovery by CO{sub 2} injection

Energy Technology Data Exchange (ETDEWEB)

Moctezuma Berthier, Andres E. [Instituto Mexicano del Petroleo, Mexico, D.F. (Mexico)

2008-07-15

Firstly are presented some basic concepts on the enhanced oil recovery; then a description is made of where the oil deposits in Mexico are located; comments are made over what has been done in Mexico in terms of enhanced oil recovery, the projects of the Instituto Mexicano del Petroleo that have dealt with the subject of enhanced oil recovery, and finally an approach is presented towards the problem of oil recovery using CO{sub 2}. [Spanish] Primeramente se presentan unos conceptos basicos sobre la recuperacion mejorada de petroleo; luego se hace una descripcion de donde se encuentran los yacimientos de petroleo en Mexico; se comenta sobre que se ha hecho en Mexico en terminos de recuperacion mejorada de petroleo; se mencionan los proyectos del Instituto Mexicano del Petroleo que han abordado el tema de la recuperacion mejorada del petroleo y por ultimo se presenta un enfoque hacia el problema de la recuperacion del petroleo usando CO{sub 2}.

Las preguntas por la calidad de la vivienda: ¿quién las hace?, ¿quién las responde?

Directory of Open Access Journals (Sweden)

Clemencia Escallón

2010-07-01

Full Text Available Este artículo presenta las distintas estrategias que ha buscado el Grupo de Investigación en Gestión y Diseño de Vivienda (GIV, del Departamento de Arquitectura de la Universidad de los Andes, para comprender y evidenciar el problema percibido sobre la calidad de la vivienda, particularmente de los sectores más pobres de la población colombiana. El enfoque se hace desde el ámbito académico con el Laboratorio de Vivienda y desde el escenario de la relación universidad-empresa según convenio de asociación con Prodesa S. A. La alerta se inicia con la preocupación por la condición de la vivienda de interés social (VIS en Bogotá: lotes estrechos, viviendas pequeñas con ubicación urbana de extrema periferia, para ir complejizando la mirada a través de preguntas como: ¿Qué facilidades urbanas tiene la ciudad en la que se construye la VIS? ¿Qué tipo de urbanizaciones o agrupaciones se están proponiendo? ¿Cuál es la espacialidad de la vivienda que se ofrece? Interesa explorar si es factible medir la calidad de la vivienda VIS, y si lo es, con qué indicadores y valoraciones se debe hacer. El artículo expone las razones de esta búsqueda, los instrumentos técnicos planteados para acercarse a las respuestas, y el análisis de los resultados y retos de la que hemos llamado “primera fase de observación”.

Simulação tridimensional adaptativa da separação das fases de uma mistura bifásica usando a equação de Cahn-Hilliard

OpenAIRE

Nós, R.L.; Ceniceros, H.D.; Roma, A.M.

2012-01-01

Simulamos a separação dos componentes de uma mistura bifásica com a equação de Cahn-Hilliard. Esta equação contém intrincados termos não lineares e derivadas de alta ordem. Além disso, a delgada região de transição entre os componentes da mistura requer muita resolução. Assim, determinar a solução numérica da equação de Cahn-Hilliard não é uma tarefa fácil, principalmente em três dimensões. Conseguimos a resolução exigida no tempo usando uma discretização semi-implícita de segunda ordem. No e...

Comparação das técnicas transarterial e de estimulação de múltiplos nervos para bloqueio do plexo braquial por via axilar usando lidocaína com epinefrina

OpenAIRE

Imbelloni, Luiz Eduardo; Beato, Lúcia; Cordeiro, José Antônio

2005-01-01

JUSTIFICATIVA E OBJETIVOS: A técnica transarterial com grandes doses de anestésico local resulta em alta efetividade para o bloqueio axilar do plexo braquial. A técnica utilizando múltiplos estímulos exige mais tempo e maior experiência. Este estudo prospectivo compara a latência e o índice de sucesso do bloqueio do plexo braquial usando duas técnicas de localização: transarterial ou múltipla estimulação dos nervos. MÉTODO: A lidocaína com epinefrina, 800 mg, foi usada inicialmente para o blo...

Solucionando dificultades en el aula: una estrategia usando el aprendizaje basado en problemas

Directory of Open Access Journals (Sweden)

Mery Luz Valderrama Sanabria

2017-09-01

Full Text Available Introducción: Se utiliza el proyecto de investigación en el aula con énfasis en el Aprendizaje Basado en Problemas, el cual promueve el aprendizaje activo y significativo, permitiendo solucionar situaciones reales de conocimiento en torno a una temática específica. Implementa los principios de la investigación formativa, como herramienta para generar nuevas alternativas en la apropiación del conocimiento. Este estudio tuvo como objetivo conocer la percepción de los estudiantes del programa Regencia de Farmacia frente a la utilización del aprendizaje basado en problemas con el fin de realizar aportes al currículo. Materiales y Métodos: Estudio descriptivo y transversal realizado con una muestra no probabilística, por conveniencia, conformada por 109 estudiantes de segundo a sexto semestre. Se elaboró un cuestionario con escala tipo Likert, sometido a valoración por expertos. Resultados: En general, los estudiantes están de acuerdo con la estrategia porque ha permitido acercarse a la investigación, fortaleciendo el pensamiento crítico; generando autonomía y responsabilidad frente al aprendizaje. A medida que avanzan los semestres, le ven mayor utilidad. Sin embargo, falta claridad en el uso de la metodología y capacitación por parte de algunos docentes para desarrollarla eficazmente. Discusión: La coordinación docente es fundamental, se debe fortalecer este aspecto para dar claridad al uso de la metodología. Implementar procesos de evaluación para determinar los avances desarrollados por los estudiantes y el impacto generado. Conclusiones: Los estudiantes consideran que adquieren conocimientos y competencias que les ayudarán en la práctica profesional.  Cómo citar este artículo: Valderrama ML, Castaño GA. Solucionando dificultades en el aula: una estrategia usando el aprendizaje basado en problemas. Rev Cuid. 2017; 8(3: 1907-18. http://dx.doi.org/10.15649/cuidarte.v8i3.456

Comparison of the pain severity, drug leakage and ecchymosis rates caused by the application on tramadol intramuscular injection in Z-track and Air-lock techniques Comparación de la severidad del dolor y las tasas de escape de líquido y equimosis causadas por la aplicación intramuscular de tramadol usando las técnicas de cámara de aire y Z-track Comparação da severidade da dor e as taxas de fuga de líquidas equimoses causadas pela aplicação intramuscular de tramadol usando as técnicas de câmaras de ar e Z-track

Directory of Open Access Journals (Sweden)

Shahla Najafidolatabad

2010-07-01

Full Text Available Objective. To compare the pain severity caused by the application of the Z-track and Air-lock intramuscular injections. Methodology. Unblinded clinical trial, where 90 female subjects aged between 18 and 60 years old were randomly assigned to two groups; the first group received the tramadol intramuscular injection using the Z-track technique (ZT and the second group received it through the air- lock method (AL. A 10 centimeter linear visual scale was used to evaluate the injection pain. The scale length was considered as the pain severity. Data were analyzed using the SPSS version 13. Groups' age, Body Mass index (BMI, and pain intensity were compared using unpaired student's t test. Results. The study showed that the pain severity of patients in the AL method group was lower than in the ZT technique group (pObjetivo. Comparar la severidad del dolor y las tasas de escape de líquido y equimosis causadas por la aplicación de las inyecciones intramusculares usando la técnica Z-track (ZT y la técnica de la cámara de aire (CA. Metodología. Este es un ensayo clínico no ciego donde un grupo de 90 mujeres entre los 18 y 60 años fueron aleatoriamente asignadas a dos grupos; El primer grupo recibió la inyección por medio de la técnica ZT y el segundo por medio de la técnica de CA. Se uso una escala visual lineal de 10 centímetros para medir la intensidad del dolor causado por la inyección. La longitud de la escala fue considerada como la severidad del dolor. Los datos fueron analizados utilizando el programa SPSS versión 13. La edad, el índice de Masa Corporal (IMC, y la intensidad del dolor de los grupos fueron comparados usando el test de la t para muestras independientes. Resultados. El estudio mostró que la severidad del dolor y las tasas de escape de líquido y equimosis en las pacientes evaluadas usando el método CA era menor que el dolor causado por la técnica ZT (p Objetivo. Comparar a severidade da dor e as taxas de escape de

Characterization of casein gene complex and genetic diversity analysis in Indian goats.

Science.gov (United States)

Rout, P K; Kumar, A; Mandal, A; Laloe, D; Singh, S K; Roy, R

2010-04-01

Milk protein polymorphism plays an important role in genetic diversity analysis, phylogenetic studies, establishing geographical diversity, conservation decision, and improving breeding goals. Milk protein polymorphism in Indian goat breeds has not been well studied; therefore, an investigation was carried out to analyze the genetic structure of the casein gene and milk protein diversity at six milk protein loci in nine Indian goat breeds/genetic groups from varied agro-climatic zones. Milk protein genotyping was carried out in 1098 individual milk samples by SDS-PAGE at alphaS1-CN (CSN1S1), beta-CN (CSN2), alphaS2-CN (CSN1S2), kappa-CN (CSN3), beta-LG, and alpha-LA loci. Indian goats exhibited alphaS1-casein A allele in higher frequency in the majority of breeds except Ganjam and local goats. The alphaS1-casein A allele frequencies varied from 0.45 to 0.77. A total of 16 casein haplotypes were observed in seven breeds and breed specific haplotypes were observed with respect to geographic region. The average number of alleles was lowest in Ganjam (1.66 +/- 0.81) and highest in Sirohi goats (2.50 +/- 1.05). Expected heterozygosity at six different loci demonstrated genetic diversity and breed fragmentation. Neighbor-Joining tree was built basing on Nei's distance. There was about 16.95% variability due to differences between breeds, indicating a strong subdivision. Principal component analysis was carried out to highlight the relationship among breeds. The variability among goat breeds was contributed by alphaS2-CN, beta-LG and alphaS1-CN. The Indian goats exhibited alphaS1-CN (CSN1S1) A allele in higher frequency in all the breeds indicating the higher casein yield in their milk.

Autoantibodies to αS1-Casein Are Induced by Breast-Feeding

Science.gov (United States)

Petermann, Klaudia; Vordenbäumen, Stefan; Maas, Ruth; Braukmann, Achim; Bleck, Ellen; Saenger, Thorsten; Schneider, Matthias; Jose, Joachim

2012-01-01

Background The generation of antibodies is impaired in newborns due to an immature immune system and reduced exposure to pathogens due to maternally derived antibodies and placental functions. During nursing, the immune system of newborns is challenged with multiple milk-derived proteins. Amongst them, caseins are the main constituent. In particular, human αS1-casein (CSN1S1) was recently shown to possess immunomodulatory properties. We were thus interested to determine if auto-antibodies to CSN1S1 are induced by breast-feeding and may be sustained into adulthood. Methods 62 sera of healthy adult individuals who were (n = 37) or were not (n = 25) breast-fed against human CSN1S1 were investigated by a new SD (surface display)-ELISA. For cross-checking, these sera were tested for anti Epstein-Barr virus (EBV) antibodies by a commercial ELISA. Results IgG-antibodies were predominantly detected in individuals who had been nursed. At a cut-off value of 0.4, the SD-ELISA identified individuals with a history of having been breast-fed with a sensitivity of 80% and a specificity of 92%. Under these conditions, 35 out of 37 sera from healthy donors, who where breast-fed, reacted positively but only 5 sera of the 25 donors who were not breast-fed. The duration of breast-feeding was of no consequence to the antibody reaction as some healthy donors were only short term breast-fed (5 days minimum until 6 weeks maximum), but exhibited significant serum reaction against human CSN1S1 nonetheless. Conclusion We postulate that human CSN1S1 is an autoantigen. The antigenicity is orally determined, caused by breast-feeding, and sustained into adulthood. PMID:22496735

Oil use of the effluent plant ETEO (Effluent Station of Oil Treatment) as combustible for generation of energy in the power plant UG-50Hz; Utulizacao de oleo da ETEO (Estacao de Tratamento de Efluentes Oleosos) para geracao de energia na UG-50Hz

Energy Technology Data Exchange (ETDEWEB)

Souza, Jose Francisco de; Nascimento, Jose Maria do; Silva, Luiz Antonio da; Salazar, Marcos Vinicios; Baptista, Reinaldo Lopes; Barros, Sueli Aguiar [Companhia Siderurgica Nacional (CSN), Volta Redonda, RJ (Brazil)

2009-11-01

The areas of finishing products of CSN Steel Plant generate contaminated effluents with oil and grease , that are treated in ETEO (Effluent Station of Oil Treatment). In this plant, the oil is processed to be sold for the consuming market. However, some seasons of the year, the market does not absorb the oil, and CSN is obliged to defray the burning of this oil, to not interrupt the productive process and cause an environmental impact. Because of this situation, we search alternatives for the viable use of this oil inside CSN steel plant, taking care for the security of the processes and the impact to the environment. This paper describes the details of the work and the implantation of the burning of this oil of the ETEO with BPF oil (type of petrochemical oil) as combustible in the boiler 7 of the power plant UG 50 Hz. For the implantation of this project, operational contingencies of security for equipment was prepared . Moreover, the work included chemical analyses of the oil and the conditions of the boiler using this mixing of oils. The reached results demonstrate the total viability of this project and it was proved another alternative of the use of this residue, with reduction of the fuel costs , steam costs and the electric energy generated in the power plant of CSN. (author)

Estimativa dos coeficientes de afetação dos custos às atividades agrícolas usando a teoria da máxima entropia

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Maria do Socorro Rosário

2014-12-01

Full Text Available Neste artigo, pretende-se estimar os coeficientes de afetação dos custos às atividades agrícolas, a partir de informação incompleta. Um modelo de desagregação dos custos de fatores de produção variáveis por atividade foi desenvolvido com base na teoria da máxima entropia e foi aplicado à região alentejo, usando os dados da base RICA de 2008. Os resultados obtidos mostram que a teoria da entropia é uma opção flexível e robusta para realizar a estimação de coeficientes de afetação dos custos das atividades num contexto de informação incompleta. Entre as duas variantes utilizadas, o modelo da entropia cruzada generalizada revelou maior capacidade de previsão, uma vez que os coeficientes estimados são mais próximos dos valores reais.

Child malnutrition in Mexico in the last two decades: prevalence using the new WHO 2006 growth standards Malnutrición preescolar en México en las últimas dos décadas: prevalencias usando los estándares de la OMS-2006

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Teresa González-de Cossío

2009-01-01

Full Text Available OBJECTIVE: To describe preschool malnutrition prevalence and trends in Mexican children for the 1988, 1999 and 2006 Mexican National Nutrition Surveys using WHO-2006 standards and National Center for Health Statistics/WHO (NCHS/WHO references. MATERIAL AND METHODS: Prevalence of undernutrition ( plus 2 z-score for weight/height were calculated. RESULTS: Height/age and weight/height have increased over time (pOBJETIVO: Describir las prevalencias y tendencias de malnutrición en preescolares mexicanos, según resultados de las Encuestas Nacionales de Nutrición 1988, 1999 y 2006, usando estándares de la Organización Mundial de la Salud de 2006 y referencias del National Center for Health Statistics/ World Health Organization (NCHS/WHO. MATERIAL Y MÉTODOS: Se calcularon prevalencias de desnutrición (puntaje z +2z peso/talla. RESULTADOS: La talla/edad y el peso/talla han aumentado con el tiempo (p< 0.05. Usando los estándares de la OMS de 2006, el desmedro en menores de cinco años de edad era de 26.9, 21.5 y 15.5% en 1988, 1999 y 2006, respectivamente. Los valores de emaciación fueron 6.2, 2.1 y 2.0%. La emaciación en 2006 en los menores de seis meses de edad fue de 4.9%. El sobrepeso aumentó de 1988 a 1999 (6.1 a 7.5% y se estabilizó en 2006 (7.6%. Las diferencias entre grupos étnicos y socioeconómicos disminuyeron con el tiempo. CONCLUSIONES: El desmedro disminuyó marcadamente, pero continúa siendo el principal problema de malnutrición. El sobrepeso emergió como problema de salud pública en niños. Las estimaciones de desnutrición en preescolares previamente publicadas usando las referencias del NCHS/WHO subestimaban las verdaderas cifras. Las desviaciones en la talla alcanzada a partir de los 12 meses de edad revelan prácticas de lactancia y alimentación infantil pobres, probablemente aunadas a infecciones tempranas. Estos resultados refuerzan la necesidad de mejorar la calidad de los programas de nutrición y de promover pr

A highly Conserved Aspartic Acid Residue of the Chitosanase from Bacillus Sp. TS Is Involved in the Substrate Binding.

Science.gov (United States)

Zhou, Zhanping; Zhao, Shuangzhi; Liu, Yang; Chang, Zhengying; Ma, Yanhe; Li, Jian; Song, Jiangning

2016-11-01

The chitosanase from Bacillus sp. TS (CsnTS) is an enzyme belonging to the glycoside hydrolase family 8. The sequence of CsnTS shares 98 % identity with the chitosanase from Bacillus sp. K17. Crystallography analysis and site-direct mutagenesis of the chitosanase from Bacillus sp. K17 identified the important residues involved in the catalytic interaction and substrate binding. However, despite progress in understanding the catalytic mechanism of the chitosanase from the family GH8, the functional roles of some residues that are highly conserved throughout this family have not been fully elucidated. This study focused on one of these residues, i.e., the aspartic acid residue at position 318. We found that apart from asparagine, mutation of Asp318 resulted in significant loss of enzyme activity. In-depth investigations showed that mutation of this residue not only impaired enzymatic activity but also affected substrate binding. Taken together, our results showed that Asp318 plays an important role in CsnTS activity.

CSN collaboration with the institutions

International Nuclear Information System (INIS)

Abenza, C.

2006-01-01

Over the years, the Directorate General of Civil Defence and Emergencies of the Ministry of the Interior and the Nuclear safety Council have increased their collaboration and improved coordination, these issues being the essential building blocks for the suitable management of an emergency. This article looks at the common history of the two departments, values the agreements reached and underlines the importance of workers with responsibilities in this area continuously updating their capacities in order to provide the public with an efficient response. (Author)

Desarrollo de un horno solar para el secado de plantas y vegetales usando control difuso

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Oscar G. Ibarra Manzano

2012-05-01

Full Text Available Recientemente, el aprovechamiento de la energía solar en el deshidratado de productos agrícolas se ha vuelto cada día más común debido a los altos rendimientos en los productos post-cosecha. La inversión en tecnologías propias para contribuir con los productores del sector agroalimentario es un factor importante para el desarrollo de las cadenas produc­tivas de nuestro país. En este trabajo se presenta el desarrollo de un horno solar para el secado de plantas y vegetales utilizando control difuso. Este es un sistema térmicamente controlado que permite disminuir el tiempo de secado de varios días a unas horas. Se reali­zaron pruebas de secado usando flor de jamaica, en las cuales se pudo disminuir el tiempo de secado de cuatro días a aproximadamente 5 h. Se presentan tanto la parte de diseño conceptual, como resultados experimentales del mismo. Los resultados obtenidos permiten ver la viabilidad del diseño propuesto.Recently, the use of solar energy in the dehydration of agricultural products is becomingmore common as high yields in the post-harvest products. Investment in technologies forcontributing to the producers of food products is an important factor for the development ofthe productive chains of our country. This paper presents the development of a solar oven fordrying plants and vegetables using fuzzy control. This is a heat-controlled system that allowsdecreasing the drying time from several days to hours. Drying tests were conducted usingjamaica flower, which could decrease the drying time from four days to about 5 h. We presentboth the conceptual design of the experimental results. The results obtained allow us to seethe feasibility of the proposed design.

Topic Modeling of Smoking- and Cessation-Related Posts to the American Cancer Society's Cancer Survivor Network (CSN): Implications for Cessation Treatment for Cancer Survivors Who Smoke.

Science.gov (United States)

Westmaas, J Lee; McDonald, Bennett R; Portier, Kenneth M

2017-08-01

Smoking is a risk factor in at least 18 cancers, and approximately two-thirds of cancer survivors continue smoking following diagnosis. Text mining of survivors' online posts related to smoking and quitting could inform strategies to reduce smoking in this vulnerable population. We identified posts containing smoking/cessation-related keywords from the Cancer Survivors Network (CSN), an online cancer survivor community of 166 000 members and over 468 000 posts since inception. Unsupervised topic model analysis of posts since 2000 using Latent Dirichlet Allocation extracted 70 latent topics which two subject experts inspected for themes based on representative terms. Posterior analysis assessed the distribution of topics within posts, and the range of themes discussed across posts. Less than 1% of posts (n = 3998) contained smoking/cessation-related terms, and covered topics related to cancer diagnoses, treatments, and coping. The most frequent smoking-related topics were quit smoking methods (5.4% of posts), and the environment for quitters (2.9% of posts), such as the stigma associated with being a smoker diagnosed with cancer and lack of empathy experienced compared to nonsmokers. Smoking as a risk factor for one's diagnosis was a primary topic in only 1.7% of smoking/cessation-related posts. The low frequency of smoking/cessation-related posts may be due to expected criticism/stigma for smoking but may also suggests a need for health care providers to address smoking and assist with quitting in the diagnostic and treatment process. Topic model analysis revealed potential barriers that should be addressed in devising clinical or population-level interventions for cancer survivors who smoke. Although smoking is a major risk factor for cancer, little is known about cancer patients' or survivors' views or concerns about smoking and quitting. This study used text mining of posts to an online community of cancer patients and survivors to investigate contexts in which

EVALUACIÓN DE LA DEGRADACIÓN Y MINERALIZACIÓN DEL MALATIÓN USANDO FOTOCATÁLISIS MEDIANTE UN COLECTOR SOLAR

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Diana Catalina Rodriguez

2010-02-01

Full Text Available Se empleó un colector solar para evaluar la degradación del malatión en una solución acuosa de 15 _g/L del plaguicida, usando tres concentraciones diferentes de dióxido de titanio (100, 200 y 250 mg/L y peróxido de hidrógeno (H2O2 al 30% como agente oxidante. La disminución de la concentración del malatión se determinó por cromatografía de gases con detector de microcaptura de electrones (CG-_ECD, previa extracción de las muestras con discos C18, y la mineralización se determinó mediante análisis de carbono orgánico total (COT. El proceso de degradación se evaluó durante 16 horas, durante las cuales, se registró la energía solar incidente mediante un radiómetro (Kipp & Zonen, modelo CUV 3. En la fotolisis se alcanzó un porcentaje de degradación de 58,8% y en la fotocatálisis, con 250 mg/L de TiO2 y 10 mL/h de H2O2, se obtuvo 98,7% de degradación. El porcentaje de mineralización alcanzado durante la fotocatálisis fue de 73%.

Modelo Bio-inspirado para el Reconocimiento de Gestos Usando Primitivas de Movimiento en Visión

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Sandra E. Nope

2008-10-01

Full Text Available Resumen: Se aborda el problema del reconocimiento de gestos usando la información de movimiento con el fin de obtener un modelo bio-inspirado para, en un futuro, utilizarlo en la programación de robots mediante el paradigma del aprendizaje por imitación. En este trabajo se extraen las primitivas de movimiento a partir de imágenes consecutivas, capturadas por una cámara web estándar. Para la programación por imitación de robots se identificó, como primera fase, el reconocimiento de gestos, en el cual es necesario resolver tres aspectos principales: La representación instantánea del movimiento, la integración temporal de dicha información y, la estrategia de clasificación. Estos tres aspectos serán tratados a lo largo de este trabajo y, en contraste con otros, la extracción del movimiento y su codificación está inspirada en el procesamiento del movimiento realizado en el cerebro de macacos. El modelo obtenido fue aplicado al reconocimiento de cuatro tipos de gestos realizados con la mano por diferentes personas. El porcentaje de aciertos varió entre 91.42% y 97.14%, utilizando diferentes estrategias estándar de clasificación. Palabras clave: Reconocimiento de gestos, modelo bio-inspirado, primitivas de movimiento, codificación del movimiento, integración temporal, visión artificial

Genetic polymorphism of beta-casein gene and its associations with milk traits in Holstein-Friesian cows

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Teodor Bugeac

2015-05-01

Full Text Available In animal breeding finding and using effective genetic markers for improving important traits it is a continuous challenge. In this respect, several genetic markers were associated in cattle with increased milk production or a better milk quality. This proved to be a useful tool for improving certain traits by selecting individuals carriers of allelic variants that have an effect on a desirable trait. In particular, positive associations between certain alleles found at the milk protein loci with some milk production traits convincingly demonstrated in several cattle breeds. Although, in some cases the results obtained in various studies were not in agreement and varied between breeds or populations. Therefore the objective of this study was to establish associations (if any between alleles found at the beta-casein (CSN2 locus and some milk production traits (milk yield and fat, protein, casein and lactose content in a Holstein-Friesian population reared in Romania. Genetic variants at CSN2 locus were identified by isoelectric focusing (IEF of milk samples. In order to determine milk composition the samples were analysed with MilkoScan FT 6000. For the statistical analysis of data SPSS v.19 for Windows was used. At the CSN2 locus four alleles and seven genotypes were identified in the analyzed cattle population. The cows carriers of CSN2 A2 allele produced the highest milk yield and the highest milk protein content, this result being in agreement with other previous studies.

Synthesis and characterization of thiolated pectin stabilized gold coated magnetic nanoparticles

Energy Technology Data Exchange (ETDEWEB)

Arora, Varun, E-mail: varun.arora3986@gmail.com [University School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Sector 16-C, Dwarka, New Delhi 110078 (India); Sood, Ankur, E-mail: ankursood02@gmail.com [University School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Sector 16-C, Dwarka, New Delhi 110078 (India); Shah, Jyoti, E-mail: shah.jyoti1@gmail.com [National Physical Laboratory, Dr. K.S. Krishnan Road, New Delhi 110012 (India); Kotnala, R.K., E-mail: rkkotnala@nplindia.org [National Physical Laboratory, Dr. K.S. Krishnan Road, New Delhi 110012 (India); Jain, Tapan K., E-mail: tapankjain@gmail.com [University School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Sector 16-C, Dwarka, New Delhi 110078 (India)

2016-04-15

Core–shell nanoparticles, magnetic core and gold shell, were synthesized by reduction of gold chloride on the surface of magnetic nanoparticles; using tyrosine as a reducing agent. The formation of gold shell on magnetic nanoparticles was confirmed by X-ray diffraction (XRD) and UV-Visible spectroscopy. The core–shell nanoparticles (CSn) were conjugated with thiolated pectin to form a stable aqueous dispersion. The hydrodynamic size of thiolated pectin stabilized core–shell nanoparticles (TP-CSn) measured by Dynamic light scattering (DLS) was 160.5 nm with a poly dispersity index (PDI) of 0.302, whereas the mean particle size of TP-CSn calculated by high resolution transmission electron microscopy (HRTEM) was 10.8 ± 2.7 nm. The value of zeta potential for TP-CSn was −13.6 mV. There was a decrease in the value of saturation magnetization upon formation of the gold shell on magnetic nanoparticles. The amount of thiolated pectin bound to the surface of core–shell nanoparticles, calculated using Thermogravimetric analysis (TGA), was 6% of sample weight. - Highlights: • Use of side group of tyrosine (phenol) as a pH dependent reducing agent to synthesize gold coated magnetic nanoparticles. • Successful coating of gold shell on magnetic nanoparticles core. • Synthesis of thiolated pectin and stabilization of aqueous dispersion of core–shell nanoparticles with thiolated pectin. • The superparamagnetic behaviour of magnetic nanoparticles is retained after shell formation.

Computerization of effluent management and external dose calculation using the 'ODCM' methodology applied to Almaraz-NPP; Mecanizacion informatica de la gestion de efluentes y calculo de dosis al exterior usando la metodologia MCDE aplicada a C.N. Almaraz

Energy Technology Data Exchange (ETDEWEB)

Garcia Gutierrez, M E [Empresarios Agrupados, A.I.E., Madrid (Spain); Sustacha Duo, D [C.N. Almaraz, Caceres (Spain)

1993-12-15

The ODCM (Offsite Dose Calculation Manual), the official operational document for all nuclear power plants develops the details for the technical specifications for discharges and governs their practical application. The use of ODCM methodology for managing and controlling data associated with radioactive discharges, as well as the subsequent processing of this data to assess the radiological impact, requires and generates a large volume of data, which demands the frequent application of laborious and complex calculation processes, making computerization necessary. The computer application created for Almaraz NPP has the capacity to store and manage data on all discharges, evaluate their effects, presents reports and copies the information to be sent periodically to the CSN (Spanish Nuclear Regulatory Commission) on a magnetic tape. The radiological impact of an actual or possible discharge can be evaluated at anytime and, furthermore, general or particular reports and graphs on the discharges and doses over time can be readily obtained. The application is run on a personal computer under a relational database management system. This interactive application is based on menus and windows. (author)

MARR project risk matrices in radiotherapy; Proyecto MARR: matrices de riesgo en radioterapia

Energy Technology Data Exchange (ETDEWEB)

Ramirez, M. L.; Perez Mulas, A.; Vilanova, J.; Prieto, C.; Delgado, J. M.; Alvarez, C.; Rodriguez, M.

2014-07-01

Radiotherapy is a complex process not without risk for the patient. The Council de Nuclear Safety (CSN), based on its cooperation with the health authorities regarding radiation protection of patient is promoting, through the project MARR, (Risk matrix in radiotherapy) the risk analysis in the radiotherapy departments of our country. This project represents the extension of methodologies applied in the nuclear sector other radiological practices. The aim is to share, with professional societies, the knowledge acquired by the CSN during its participation in the Ibero-American Forum of regulators (Forum) projects. (Author)

CORRECCIONES DIFERENCIALES VÍA NTRIP PARA DISPOSITIVO MÓVIL CON APLICACIÓN ANDROID

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Alfonso Tierra

Full Text Available El posicionamiento en tiempo real usando GPS se hace mediante correcciones diferenciales enviadas desde una estación base hacia un receptor móvil. Generalmente, la corrección es enviada vía radio o por medio de satélites de comunicación. Con el desarrollo del internet inalámbrica y con el aumento de la cobertura de la señal mediante un Protocolo, conocido como IP, han hecho que se integren estas tecnologías para realizar mediciones para trabajos y estudios en tiempo real usando la tecnología GPS, y mediante el protocolo NTRIP. Esta técnica se ha estado desarrollando e implementando de forma constante en la región, siendo el presente y futuro de las mediciones para trabajos de precisión y en tiempo real. En este trabajo, se muestra la implementación de la técnica NTRIP para posicionamiento en tiempo real. El acceso a datos brutos del GPS en un móvil ANDROID y un navegador Mobile Mapper 10, la utilización de NTRIP para el envió de correcciones diferenciales por medio del protocolo IP, y el internet como red de información inmediata, fueron la base general para crear una aplicación que utiliza una corrección diferencial por posición. Los primeros resultados muestran una mejoría en la posición, pudiendo llegar a obtener un error medio de 2.3m en una Tablet con Android, y 1.6 m con el Mobile Mapper 10; en un tiempo de 5 minutos

A cDNA microarray, UniShrimpChip, for identification of genes relevant to testicular development in the black tiger shrimp (Penaeus monodon

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Klinbunga Sirawut

2011-04-01

Full Text Available Abstract Background Poor reproductive maturation in captive male broodstock of the black tiger shrimp (Penaeus monodon is one of the serious problems to the farming industries. Without genome sequence, EST libraries of P. monodon were previously constructed to identify transcripts with important biological functions. In this study, a new version of cDNA microarray, UniShrimpChip, was constructed from the Peneaus monodon EST libraries of 12 tissues, containing 5,568 non-redundant cDNA clones from 10,536 unique cDNA in the P. monodon EST database. UniShrimpChip was used to study testicular development by comparing gene expression levels of wild brooders from the West and East coasts of Thailand and domesticated brooders with different ages (10-, 14-, 18-month-old. Results The overall gene expression patterns from the microarray experiments revealed distinct transcriptomic patterns between the wild and domesticated groups. Moreover, differentially expressed genes from the microarray comparisons were identified, and the expression patterns of eight selected transcripts were subsequently confirmed by reverse-transcriptase quantitative PCR (RT-qPCR. Among these, expression levels of six subunits (CSN2, 4, 5, 6, 7a, and 8 of the COP9 signalosome (CSN gene family in wild and different ages of domesticated brooders were examined by RT-qPCR. Among the six subunits, CSN5 and CSN6 were most highly expressed in wild brooders and least expressed in the 18-month-old domesticated group; therefore, their full-length cDNA sequences were characterized. Conclusions This study is the first report to employ cDNA microarray to study testicular development in the black tiger shrimp. We show that there are obvious differences between the wild and domesticated shrimp at the transcriptomic level. Furthermore, our study is the first to investigate the feasibility that the CSN gene family might have involved in reproduction and development of this economically important

IDENTIFICACIÓN DEL AGENTE CAUSAL DE LA ANTRACNOSIS DE Sansevieria spp. EN COSTA RICA

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Gerardo Pérez-León

2013-01-01

Full Text Available Sansevieria spp. (Agavaceae es una ornamental de follaje originaria de África y Asia. S. trifasciata (St es la especie con mayor número de cultivares en el mercado de exportación de Costa Rica a Estados Unidos y Holanda. Muestras foliares de S. trifasciata var. “Hahnii” con lesiones circulares y acuosas (algunas alargadas y secas, fueron analizadas. El patógeno recuperado fue identificado como Colletotrichum sansevieriae Nakamura (CsN mediante pruebas de patogenicidad, morfología y técnicas moleculares. Los aislamientos mono-hifales presentaron coloración crema, crecimiento postrado y escasa producción de conidios. La patogenicidad de CsN se evaluó en 7 variedades de St; Sansevieriasp., var., jiboia; S. cylindrica y las ornamentalesCodiaeum variegatum, Cordelyne terminalis y Dracaena deremensis, mediante 2 sistemas deinoculación: plantas en maceta (invernaderoy hojas separadas (laboratorio; con ambos sereprodujeron los síntomas de la enfermedad. Cinco de las variedades de S. trifasciata desarrollaron síntomas, “Hahnii” la más susceptible. Ninguna de las otras ornamentales presentósíntomas. CsN fue re-aislado de hojas inoculadas (postulados de Koch. La amplificación mediante PCR de la región ITS con los iniciadores ITS5 e ITS4 produjo un fragmento de aproximadamente 600pb, cuya secuencia de nucleótidos fue idéntica para los aislamientos mono-hifales. En el Banco de Genes, la secuencia alineó con accesiones de CsN de Australia y USA, con un índice de simi laridad del 99 al 100%. El análisis filogenético, con base en la región ITS2, agrupó (99% valor debootstrap los aislamientos costarricenses con elaislamiento tipo CsN de Japón y los de Australia y USA. Hasta donde se conoce, éste es el primer informe de la antracnosis de Sansevieria en C. R.

Allowance for aging in Spanish nuclear power plants

International Nuclear Information System (INIS)

Rodriguez, C.

2009-01-01

In Spain, as in most European Union countries, the nuclear power plants (NPP) operation license is open regarding its duration, there being no legal restrictions for extending the operational life of the NPP by renewing their licenses. Plant operation permits are renewed every ten years, following the performance of periodic safety reviews, which constitute a reasonable guarantee that safety conditions will be maintained throughout the next ten years period. Plant ageing management programmes in Spain started in mid 80's with a joint programme shared by all Spanish utilities through their common organisation, U.N.E.S.A., and the Spanish nuclear regulatory Authority (C.S.N.). The development of the methodology was based mainly in technical documents from IAEA and from U.S.N.R.C. rulemaking and documents, as well as in the international experience available. C.S.N. is interested in realising an effective management of components ageing processes. Therefore C.S.N. has introduced within its inspection and control functions specific requirements related to ageing management. The regulatory requirements related to NPP lifetime management are basically the following: NPP operation license requires preparing and submitting to the C.S.N. an annually updated report on the ageing control activities or the Lifetime Management Programme; - continuous NPP safety evaluation process by C.S.N., complemented with periodic safety reviews, to be performed every 10 years, including: a) review of components behaviour (identify degradation mechanism and current corrective measures adopted by the plant for ageing mechanisms control and mitigation) and b) updating of the safety evaluation and improvement programmes (Lifetime management programme is included among them). In the case the period of validity of a new operation permit exceeds the lifetime considered in the initial design of the plant, the periodic safety review process remains valid, but it must be supplemented with additional

ANÁLISIS TERMODINÁMICO DE UN SISTEMA DE REFRIGERACIÓN SOLAR POR ABSORCIÓN USANDO SOLUCIONES DE MONOMETILAMINA - AGUA PARA LA CONSERVACIÓN DE ALIMENTOS ANÁLISE TERMODINÁMICA DUM SISTEMA DE REFRIGERAÇÃO SOLAR POR ABSORÇÃO USANDO COMO PARELHA MONOMETILAMINA - AGUA PARA A CONSERVA DE ALIMENTOS THERMODYNAMIC ANALYSIS OF A SOLAR ABSORPTION REFRIGERARON SYSTEM USING MONOMETHYLAMINE - WATER SOLUTIONS FOR FOOD STORAGE

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CESAR A. ISAZA

2010-06-01

Full Text Available Este trabajo presenta la viabilidad de los sistemas de refrigeración solar por absorción usando soluciones de monometilamina - agua (MMA-A para aplicaciones en conservación de alimentos en las regiones rurales de Colombia, sin acceso a la red de energía eléctrica. Para suplirlos requerimientos de energía térmica se propone un sistema de calentamiento de agua con energía solar usando colectores de placa y un sistema de respaldo convencional. En este trabajo se determinó el coeficiente de operación (COP del sistema de refrigeración solar por absorción de una sola etapa en función de la temperatura en los diferentes componentes del ciclo. Los resultados indican que el sistema podría mejorarse mediante un mejor diseño en el intercambiador de calor de solución, el evaporador y el rectificador. Los resultados teóricos demuestran que el uso de la solución de MMA-A puede ser usada en sistemas de refrigeración por absorción operados con energía térmica de baja calidad, tales como la energía solar.Este trabalho apresenta a viabilidade e aplicabilidade dos sistemas de refrigeração solar por absorção usando como parelha a monometilamina - agua (MMA-W para fins de conservação de alimentos ñas regiões rurais da Colômbia, onde não há energía disponível. Propõese um sistema de calefação solar mediante coletores solares de placa plana com um sistema convencional de aquecimento auxiliar para suprir as necessidades energéticas do refrigerador por absorção. Determinou-se o coeficiente de desempenho (COP do sistema de refrigeração solar por absorção só de uma etapa em funçã da temperatura nos diferentes componentes do ciclo. Os resultados indicam que o sistema poderia se melhorar mediante um desenho melhorno intercambiador de calor de solução, o evaporador e o retificador os resultados teóricos demonstram que o uso da solução de MMA-W pode ser usada em sistemas de refrigeração como parelha absortiva operado

Comparação das técnicas transarterial e de estimulação de múltiplos nervos para bloqueio do plexo braquial por via axilar usando lidocaína com epinefrina Comparación de las técnicas transarterial y de estimulación de múltiples nervios para bloqueo del plexo braquial por vía axilar usando lidocaína con epinefrina Comparison of transarterial and multiple nerve stimulation techniques for axillary block using lidocaine with epinephrine

OpenAIRE

Luiz Eduardo Imbelloni; Lúcia Beato; José Antônio Cordeiro

2005-01-01

JUSTIFICATIVA E OBJETIVOS: A técnica transarterial com grandes doses de anestésico local resulta em alta efetividade para o bloqueio axilar do plexo braquial. A técnica utilizando múltiplos estímulos exige mais tempo e maior experiência. Este estudo prospectivo compara a latência e o índice de sucesso do bloqueio do plexo braquial usando duas técnicas de localização: transarterial ou múltipla estimulação dos nervos. MÉTODO: A lidocaína com epinefrina, 800 mg, foi usada inicialmente para o blo...

El poder de la organización informal en la gestión administrativa

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Luis Enrique González Salazar

2003-01-01

Full Text Available En este artículo se hace un análisis etnográfico del poder de la organización informal en las organizaciones educativas frente al contexto formal que representa la figura de el administrador o la administradora educativa de las direcciones cinco del circuito 01 de la Dirección Regional de Educación de Alajuela. Se propone una revisión profunda por parte del director o la directora sobre el rol y la función que desempeña la organización informal, pistas para su caracterización, cinco juegos de poder que juegan, los motivos y afiliaciones de los grupos informales del personal docente y administrativo de las instituciones del circuito 01 de la DREA. Pistas y sugerencias que permiten al administrador educativo liberar el potencial energético de la organización informal, y así, establecer una nueva manera de sinergiar esfuerzos para el logro de los objetivos institucionales, usando como base el poder de la organización informal

UTILIZACIÓN DE SOFTWARE DE CORRECCIÓN AUTOMÁTICA EN EL CAMPO DE LAS CIENCIAS DE LA SALUD

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Ferrán Prados

2010-07-01

Full Text Available Estamos viviendo una época de cambios profundos en la educación universitaria. La implantación del plan de Bolonia nos ha llevado a plantear nuevas metodologías docentes, a revisar el papel del estudiante, la evaluación por competencias, la incorporación de las TIC. Hechos impensables hace poco más de una década. Entre las diferentes plataformas informáticas, cabe destacar las que permiten corrección automática de ejercicios, porque son instrumentos de un gran interés pedagógico ya que evalúan al instante al alumnado y aportan un feedback del conocimiento que tiene en forma de mensaje de ayuda o de nota. Si la potencia de estas herramientas la sumamos a la de Internet, usando un entorno de e-learning, el resultado permitirá trabajar, corregir, evaluar, resolver dudas, etc., desde cualquier lugar y a cualquier hora. Este trabajo presenta parte de una plataforma y los resultados de su utilización en el ámbito de las ciencias de la salud.

MODELO DE ENSEÑANZA DE ASIGNATURAS B-LEARNING EN UNIVERSIDAD TECNOLÓGICA DE CHILE-INACAP CONCEPCIÓN- TALCAHUANO. RESULTADOS ACADÉMICOS DE 4 AÑOS DE EXPERIENCIA

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Arnold Schirmer Prieto

2010-01-01

Full Text Available Este estudio describe la experiencia de la metodología b-learning aplicada desde hace 4 años en las asignaturas de Administración de RR.HH. y Prevención de Riesgos en la Universidad Tecnológica de Chile (Inacap, Concepción-Talcahuano. Se presentan datos que permiten mostrar la efectividad de la metodología en términos de rendimiento académico y reflexionar sobre las dificultades propias de la metodología b-learning y las oportunidades de mejoramiento, exponiendo un modelo de enseñanza-aprendizaje aplicado. El propósito de esta investigación es servir de aporte a los procesos educativos bajo una temática virtual, específicamente con métodos de enseñanza híbrida donde, por el uso de nuevas prácticas pedagógicas usando TIC's, necesitan de una gestión y práctica de una didáctica específica para cumplir de manera eficiente y efectiva su objetivo.

ANÁLISIS COMPUTACIONAL DEL EFECTO DE POLIMORFISMOS DE GENES DEL SISTEMA m-CALPAÍNA/CALPASTATINA SOBRE LA CALIDAD DE LA CARNE BOVINA

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J. D. Leal-Gutiérrez

2015-01-01

Full Text Available Los genes del sistema de enzimas μ-Calpaína/Calpastatina han sido ampliamente evaluados en estudios de asociación respecto de parámetros de calidad cárnica como la terneza; previamente se han identificado varios polimorfismos asociados con la variación fenotípica en poblaciones no relacionadas de bovinos. Usando herramientas computacionales se logró postular la asociación de cuatro polimorfismos encontrados en μ-Calpaína y 11 en Calpastatina que producen una alteración de los parámetros físico-químicos, tanto del ARNm (estabilidad y polimorfismo conformacional, como de la proteína (punto isoeléctrico, potencial electroestático y superficie molecular. Es importante poder establecer el soporte biológico de polimorfismos genéticos asociados con parámetros fenotípicos que mejoren la productividad animal, lo que hace que la aproximación in silico se convierta en una herramienta útil para tal fin.

Análise da eficiência do mercado futuro brasileiro de boi gordo usando co-integração

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André Steffens Moraes

2009-09-01

Full Text Available A hipótese de que os preços futuros são preditores não viesados dos preços à vista é uma hipótese conjunta de que os mercados são eficientes e que não existe prêmio ao risco. Entretanto, na presença de prêmio ao risco, a hipótese de não viés pode ser rejeitada mesmo quando o mercado é eficiente. Este artigo testa a eficiência do mercado futuro brasileiro do boi gordo na presença de prêmio ao risco, usando técnicas de co-integração. Os resultados mostram que o mercado futuro do boi gordo é eficiente e não viesado no longo prazo, independente da presença de prêmio ao risco.The hypothesis that future prices are unbiased predictors of spot prices is a joint hypothesis that markets are efficient and risk premium are absent. However, the unbiasedness hypothesis may be rejected in the presence of a risk premium, even when the market is efficient. The objective of this article is to test market efficiency for the Brazilian live cattle while permitting the presence of risk premium, using cointegration techniques. Results show that the future markets for live cattle are efficient and unbiasedness in the long run, and does not depend of the presence of a risk premium.

Generation of beta-lactoglobulin knock-out goats using CRISPR/Cas9.

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Wenjun Zhou

Full Text Available Goat's milk, considered a substitute for cow's milk, has a high nutritional value. However, goat's milk contains various allergens, predominantly β-lactoglobulin (BLG. In this study, we employed the CRISPR/Cas9 system to target the BLG locus in goat fibroblasts for sgRNA optimization and generate BLG knock-out goats through co-injection of Cas9 mRNA and small guide RNAs (sgRNAs into goat embryos at the one-cell stage. We firstly tested sgRNA editing efficiencies in goat fibroblast cells, and approximately 8.00%-9.09% of the cells were modified in single sgRNA-guided targeting experiment. Among the kids, the genome-targeting efficiencies of single sgRNA were 12.5% (10 ng/μL sg1 and 0% (10 ng/μL sg2 and efficiencies of dual sgRNAs were 25.0% (25 ng/μL sg2+sg3 group and 28.6% (50 ng/μL sg2+sg3 group. Relative expression of BLG in BLG knock-out goat mammary glands significantly (p < 0.01 decreased as well as other milk protein coding genes, such as CSN1S1, CSN1S2, CSN2, CSN3 and LALBA (p < 0.05. As expected, BLG protein had been abolished in the milk of the BLG knock-out goat. In addition, most of the targeted kids were chimeric (3/4, and their various body tissues were edited simultaneously. Our study thus provides a basis for optimizing the quality of goat milk, which can be applied to biomedical and agricultural research.

¿ Como se hace una Telenovela ?

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Iván Gavaldón

2015-01-01

Full Text Available La autora relata la historia de las Relaciones Públicas y dice que surgieron y se desarrollaron para legitimar ante el público los intereses económicos y políticos de quienes detentan el poder. Se cuestiona sobre el por qué no aplicar las relaciones públicas, en organizaciones populares, para que mejoren su publicación y orienten sus propósitos de desarrollo. El tema que aborda las Políticas culturales en América Latina acopia un extracto de lo más trascendente de los ensayos del libro editado por Néstor García Canclini. Sobre la telenovela se afirma que esta ha llegado a ser uno de los instrumentos más importantes de la comunicación popular: por ella desfilan las identidades de las más variadas culturas brasileñas. Y en cuanto a la caricatura se relata lo que ocurrió en el Seminario taller " Caricatura y Periodismo", realizado el(9-11 de Nov.- 1987 en el CIESPAL. El estudio sobre el mercado del vídeo se ve dificultado por la imprecisión de los datos obtenidos. Los datos oficiales no siempre se aproximan a la realidad, pues el mercado de vídeo se instauró en América Latina partiendo de una lógica totalmente diversa de los equipos de sonido e imagen.

COMPARISON BETWEEN CONVENTIONAL AND ORGANIC RICE USING PHOTOACOUSTIC TECHNIQUE

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FERNANDO GORDILLO DELGADO

2012-01-01

Full Text Available El arroz (Oryza sativa hace parte de los alimentos básicos para más de la mitad de la población mundial. Este cereal aporta grandes cantidades de calorías al consumidor. La utilización de herbicidas y de fertilizantes de origen sintético en los cultivos genera no sólo gran deterioro ambiental sino también la contaminación del fruto poniendo en riesgo la salud del consumidor. Por otro lado, la producción "orgánica" necesita de certificación, que normalmente se hace a través de un proceso de inspección que resulta ser engorroso y caro. Por esta razón es pertinente la búsqueda de criterios científicos de discriminación que permitan realizar este procedimiento con mayor garantía y a menor costo. En este trabajo se presentan los resultados obtenidos del análisis espectroscópico hecho a muestras de arroz variedad Combeima (cascarilla y grano blanco, recolectadas de cultivos tratados con técnicas orgánicas y convencionales, usando la técnica fotoacústica resuelta en longitud de onda. También se compararon sus parámetros termofísicos medidos con la misma técnica resuelta en frecuencia. Finalmente, se observó la morfología celular del grano a través de micrografías tomadas con microscopio óptico. Los resultados permitieron determinar diferencias importantes que pueden servir al propósito de la certificación.

Compósitos polímero-madeira preparados por polimerização in situ de metil metacrilato usando aditivos bifuncionais

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Bruno Dufau Mattos

2015-12-01

Full Text Available Resumo O presente trabalho teve por objetivo a confecção de compósitos polímero-madeira por meio de polimerização in situ de metil metacrilato (MMA, utilizando ácido metacrílico (MAA e glicidil metacrilato (GMA como agentes de ligação e reticulação. Amostras de madeira de guapuruvu foram impregnadas em um sistema de vácuo e pressão e polimerizadas em estufa a 90°C por 10h, usando 1,5% de peroxido de benzoíla como catalisador. Os compósitos foram caracterizados por meio de testes de absorção de água e estabilidade dimensional, molhabilidade, ATR-IR, TGA, MEV e WPG. Os espectros de ATR-IR mostraram incrementos nas bandas a 1746, 1460, e 1145 cm–1, referentes as estruturas químicas dos polímeros dentro da madeira, confirmado posteriormente pelas imagens de MEV. A termogravimetria apontou reações químicas entre os copolímeros e a parede celular da madeira nos compósitos com GMA e MAA. Os compósitos preparados com MMA apresentaram incrementos acima de 50% nas propriedades higroscópicas e de estabilidade dimensional, entretanto a adição de GMA e MAA resultou em maiores incrementos nas mesmas propriedades, entre 66-90%.

DelPapa - Aplicativo computacional para a análise de dados de experimentos no delineamento blocos ao acaso, usando o método Papadakis

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Lindolfo Storck

2015-05-01

Full Text Available O aplicativo computacional para a análise de dados de experimentos executados no delineamento blocos ao acaso, por meio do método usual e de Papadakis, foi desenvolvido em sua primeira versão (não publicada, na linguagem de programação Pascal. Considerando que o método de Papadakis foi eficiente para as principais culturas agrícolas (milho, soja, feijão e trigo e, para tornar o aplicativo mais amigável, a versão em Pascal foi reprogramada em Java, cuja denominação é DelPapa. Este aplicativo realiza a análise de variância segundo o delineamento blocos ao acaso pelo método usual (estima parâmetros genéticos, medidas de qualidade experimental e testes dos pressupostos da análise de variância e pelo método de Papadakis. Usando as médias ajustadas pela covariável (média dos erros das parcelas vizinhas, também realiza o teste Scott e Knott (P=0,05 para agrupar os tratamentos.

Modelación númerica de procesos de esterilización térmica de alimentos usando volúmenes de control: Aproximación cilíndrica./Numerical simulation of thermal sterilization process of foods using control volumes: Cylindrical aproximation.

OpenAIRE

Ciro Velásquez, Héctor José; González, Carlos; García, Eduardo

2009-01-01

Un proceso de esterilización térmica de alimentos fue modelado usando la técnica de diferenciación finita aplicada a volúmenes de control. El modelo de simulación fue desarrollado en coordenadas cilíndricas con un ejemplo de aplicación tomando como referencia un producto cárnico (carne de res). Los resultados de la simulación mostraron que el algoritmo desarrollado es independiente de la red nodal seleccionada, permitiendo cuantificar las curvas de penetración de calor en el punto crítico del...

A reverse method to estimate initial temperatures in geothermal reservoirs; Un metodo inverso para estimacion de la temperatura inicial de yacimientos geotermicos

Energy Technology Data Exchange (ETDEWEB)

Garcia Gutierrez, Alfonso [Instituto de Investigaciones Electricas, Gerencia de Geotermia, Cuernavaca, Morelos (Mexico)]. E-mail: aggarcia@iie.org.mx; Ramos Alcantara, Jose R. [Centro Nacional de Investigacion y Desarrollo Tecnologico, Departamento de Ingenieria Mecanica, Cuernavaca, Morelos (Mexico); Arellano Gomez, Victor M. [Instituto de Investigaciones Electricas, Gerencia de Geotermia, Cuernavaca, Morelos (Mexico)

2010-01-15

A method is presented for estimating the initial temperature in geothermal-reservoir formations. The method is based on control theory where the measured temperatures or temperature logs are compared with corresponding simulated temperatures for different times with the well closed. The comparison is made using a control algorithm that makes changes to the originally assumed reservoir temperatures and performs iterations until the best fit between the temperature logs and the simulated temperatures is obtained. The simulation of fluid transport and heat in the well includes the processes of circulation and stop in the presence of circulation losses, modeled on macroscopic balances of momentum and energy. The transport processes in the formation regard the reservoir as an isotropic porous medium and fluid flow is described by Darcy's law. This model generates the fields of temperatures, pressures and speeds as a function of time and space. The method was tested with data from well LV-3 in Las Tres Virgenes geothermal field, Baja California Sur, Mexico. The estimated temperatures of the undisturbed formation-or initial temperatures-are compared within {+-}15 degrees Celsius with the measured temperatures, which is an acceptable outcome from an engineering point of view. [Spanish] Se presenta un metodo para la estimacion de la temperatura inicial en las formaciones de yacimientos geotermicos. El metodo se basa en la teoria de control donde las temperaturas medidas o registros de temperatura se comparan con las correspondientes temperaturas simuladas a diferentes tiempos con el pozo cerrado. La comparacion se hace usando un algoritmo de control el cual hace cambios a las temperaturas de yacimiento originalmente supuestas y realiza iteraciones hasta que se obtiene el mejor ajuste entre los registros de temperatura y las temperaturas simuladas. La simulacion del transporte de fluidos y calor en el pozo incluye los procesos de circulacion y paro en presencia de

Interação terapêutica em saúde mental usando a teoria da aprendizagem mediada Interacción terapéutica en la salud mental usando la teoría de aprendizaje mediada Therapeutical interaction in mental health using the mediated learning theory

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Ana Cristina Barros da Cunha

2009-09-01

Full Text Available A relação terapeuta/paciente de saúde mental e as consequências do padrão interativo entre ambos foram discutidas com base na Teoria da Experiência de Aprendizagem Mediada, proposta por R. Feuerstein. Usando uma proposta de operacionalização da Escala de Avaliação de Experiência de Aprendizagem Mediada de C. S. Lidz, analisou-se o padrão de mediação adotado por uma terapeuta na interação com dois pacientes. Terapeuta e pacientes foram observados em 15 sessões de interação em atividades de socialização. Os dados foram transcritos em registro cursivo e analisados segundo a proposta de operacionalização citada. Os resultados mostraram que a terapeuta adotou um padrão de mediação adequado nos principais critérios da Escala. Isto, por sua vez, demonstrou que a terapeuta intencionalmente envolvia os pacientes nas atividades propostas, enfatizando e atribuindo valor positivo às atitudes destes; além disso, a terapeuta se referia aos eventos do passado/futuro para estabelecer relações entre os elementos envolvidos na atividade e o conhecimento do paciente em seu processo de aprendizagem.La relación entre el terapeuta y el paciente de la salud mental y las consecuencias del modelo de interacción entre ambos fueron examinadas utilizando la Teoría de Aprendizaje Mediada, ofertada por R. Feuerstein. Usando una aplicación práctica de la propuesta de la Escala de Avaliación de Experiencia de Aprendezaje Mediada de C. S. Lidz, se analizó el patrón de mediacción que una terapeuta ha adoptado con dos pacientes. La terapeuta y el paciente se observaron en 15 situacciones de interacción en actividades de socialización. Los datos fueron analizados utilizando una aplicación práctica de la propuesta anterior. Los resultados demostraron que la terapeuta ha adoptado un excelente modelo de mediación para los principales criterios de la escala. Se mostró que el terapeuta intencionalmente envolvía los pacientes em las

Energy expenditures & physical activity in rats with chronic suboptimal nutrition

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Lifshitz Fima

2006-01-01

Full Text Available Abstract Background Sub-optimally nourished rats show reduced growth, biochemical and physiological changes. However, no one has assessed metabolic rate adaptations in rats subjected to chronic suboptimal nutrition (CSN. In this study energy expenditure (EE; kcal/100 g body weight and physical activity (PA; oscillations in weight/min/kg body weight were assessed in rats subjected to three levels of CSN. Results Body weight gain was diminished (76.7 ± 12.0 and 61.6 ± 11.0 g in rats fed 70 and 60% of the ad-libitum fed controls which gained more weight (148.5 ± 32.3 g. The rats fed 80% gained weight similarly to controls (136.3 ± 10.5 g. Percent Fat-free body mass was reduced (143.8 ± 8.7 and 142.0 ± 7.6 g in rats fed 70 and 60% of ad-libitum, but not in those fed 80% (200.8 ± 17.5 g as compared with controls (201.6 ± 33.4 g. Body fat (g decreased in rats fed 80% (19.7 ± 5.3, 70% (15.3 ± 3.5 and 60% (9.6 ± 2.7 of ad-libitum in comparison to controls (26.0 ± 6.7. EE and PA were also altered by CSN. The control rats increased their EE and PA during the dark periods by 1.4 ± 0.8 and 1.7 ± 1.1 respectively, as compared with light the period; whereas CSN rats fed 80 and 70% of ad-libitum energy intake had reduced EE and PA during the dark periods as compared with the light period EE(7.5 ± 1.4 and 7.8 ± 0.6 vs. 9.0 ± 1.2 and 9.7 ± 0.8; p Conclusion CSN rats adapt to mild energy restriction by reducing body fat, EE and PA mainly during the dark period while growth proceeds and lean body mass is preserved. At higher levels of energy restrictions there is decreased growth, body fat and lean mass. Moreover EE and PA are also reduced during both light and dark periods.

Longitudinal data analysis of polymorphisms in the κ-casein and β-lactoglobulin genes shows differential effects along the trajectory of the lactation curve in tropical dairy goats.

Science.gov (United States)

Cardona, Samir Julián Calvo; Cadavid, Henry Cardona; Corrales, Juan David; Munilla, Sebastián; Cantet, Rodolfo J C; Rogberg-Muñoz, Andrés

2016-09-01

The κ-casein (CSN-3) and β-lactoglobulin (BLG) genes are extensively polymorphic in ruminants. Several association studies have estimated the effects of polymorphisms in these genes on milk yield, milk composition, and cheese-manufacturing properties. Usually, these results are based on production integrated over the lactation curve or on cross-sectional studies at specific days in milk (DIM). However, as differential expression of milk protein genes occurs over lactation, the effect of the polymorphisms may change over time. In this study, we fitted a mixed-effects regression model to test-day records of milk yield and milk quality traits (fat, protein, and total solids yields) from Colombian tropical dairy goats. We used the well-characterized A/B polymorphisms in the CSN-3 and BLG genes. We argued that this approach provided more efficient estimators than cross-sectional designs, given the same number and pattern of observations, and allowed exclusion of between-subject variation from model error. The BLG genotype AA showed a greater performance than the BB genotype for all traits along the whole lactation curve, whereas the heterozygote showed an intermediate performance. We observed no such constant pattern for the CSN-3 gene between the AA homozygote and the heterozygote (the BB genotype was absent from the sample). The differences among the genotypic effects of the BLG and the CSN-3 polymorphisms were statistically significant during peak and mid lactation (around 40-160 DIM) for the BLG gene and only for mid lactation (80-145 DIM) for the CSN-3 gene. We also estimated the additive and dominant effects of the BLG locus. The locus showed a statistically significant additive behavior along the whole lactation trajectory for all quality traits, whereas for milk yield the effect was not significant at later stages. In turn, we detected a statistically significant dominance effect only for fat yield in the early and peak stages of lactation (at about 1-45 DIM

The Nuclear Safety Council in the National System of Nuclear and Radiological Emergencies. Functions, organization and new international trends; El Consejo de Seguridad Nuclear en el Sistema Nacional de Emergencias Nucleares y Radiológicas. Funciones, organización y nuevas tendencias internacionales

Energy Technology Data Exchange (ETDEWEB)

Mozas García, A.; Martín Calvarro, J.M.; García Cadierno, J.P.; Calvín Cuartero, M.

2015-07-01

This article describes the role of the Spanish Nuclear Safety Council (CSN) in the coordination of nuclear and radiológicas emergencies, and how they engage with the National Nuclear and Radiological Emergency System. To accomplish its functions, the CSN, has set up the Emergency Response Organization (ORE), which structure, functions and procedures are also described in this work. Finally, the new international trends that are being developed on emergency preparedness and response as a consequence of the lessons learned from recent disasters are reported. [Spanish] Este artículo revisa las funciones que el Consejo de Seguridad tiene en la coordinación de las emergencias nucleares y radiológicas, y cómo se engranan éstas en el Sistema Nacional de Emergencias. A partir de las funciones que tiene encomendadas se describe la organización del CSN en emergencias y la estructura de los apoyos con los que cuenta para cumplir con aquéllas. Por último, se revisan las tendencias que, a nivel internacional, se están desarrollando para incorporar a la preparación de la respuesta a emergencias las lecciones aprendidas de las últimas catástrofes ocurridas.

Cinética de adsorción de Cr (VI usando biomasas residuales modificadas químicamente en sistemas por lotes y continuo

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Candelaria Tejada Tovar

2015-06-01

Full Text Available Se estudia la adsorción de Cr (VI a partir de biomasa residual: bagazo de palma y cáscaras de ñame, además se estudia la modificación con ácido cítrico de las biomasas. La determinación del metal en solución fue llevada a cabo usando el método de la 1,5-difenilcarbazida. Del análisis FTIR se encontró que los grupos hidroxilo y carbonilo presentes en los adsorbentes son los de mayor contribución al proceso de remoción. Además, la modificación mejora la eficiencia del metal de acuerdo con la isoterma de Langmuir de 13 a 4mg/g para el bagazo de palma, y de 22 a 26mg/g para las cáscaras de ñame. Se establece además una mejora en el proceso al trabajar las biomasas en sistema continuo. De las condiciones óptimas de adsorción se determinó que el pH de 2 y el tamaño de partícula de 1mm son las que más favorecen el proceso, y el modelo de Elovich el que mejor lo describe.

Task related doses in spanish light water reactors over the period 1990-1996

International Nuclear Information System (INIS)

Aroca, J.; Montesinos, J.J.; O'Donnell, P.; Amor, I.; Butragueno, J.L.

1998-01-01

In order to evaluate in depth the effectiveness of the practical application of the ALARA principle in Spanish nuclear facilities -7 PWR (6 Westinghouse and 1 KWU-Siemens) and 2 BWR (Generic Electric), and to have a further overview of dose trends, the CSN has analysed the task related doses data over the period 1990-1996. The scope of this analysis includes the collective dose and relative relevance for 18 different refuelling outage tasks, some sub-tasks, 12 department staff, and the main consolidated dose reduction-techniques and good practices. Data has been collected from the outage reports NPPs provide according to the CSN 1.5 Safety Guide format. (Author)

Strategies of NSC in radiation protection

International Nuclear Information System (INIS)

Lentijo, J. C.; Gil, E.; Rodriguez, M.; Ramos, L. M.

2004-01-01

The Spanish radiation protection model is consistent with the recommendations established in the ICRP-60, and it is strongly implemented in all practices and related activities of the country. the practical implementation of that model is assuring a high level of protection of workers, public and environment. The Nuclear Safety Council (CSN), as Spanish regulator, is currently involved in the implementation of a new Strategic Plan, which contains, among others, strategic and operational objectives to improve the national system of radiation protection, so they will drive the activities of the CSN in this field during the coming years. A summary of those objectives and the related action plan are described. (Author)

Emergency lighting system for compliance with the IS-30 and further than the foundations of design events

International Nuclear Information System (INIS)

Tejeda Sanchez, C.

2014-01-01

Autonomy and vulnerability to fire requirements of the emergency lighting systems, established in CSN instruction IS-30, and in commitments to deal with the consequences of events more beyond the bases of design, the design of a new lighting system required of emergency in the Almaraz Nuclear power plant. The design process consists of three phases: study of needs, definition of detailed design and requirements. During these phases is defined distribution and models luminaire lighting studies and specifications. Through the adaptation of the system to the needs of each area of the plant is It achieves compliance with the objectives defined by the CSN. (Author)

Emergency lighting system for compliance with the IS-30 and further than the foundations of design events; Sistema de Alumbrado de Emergencia para cumplimiento con la IS-30 y sucesos mas alla de las bases de diseno

Energy Technology Data Exchange (ETDEWEB)

Tejeda Sanchez, C.

2014-07-01

Autonomy and vulnerability to fire requirements of the emergency lighting systems, established in CSN instruction IS-30, and in commitments to deal with the consequences of events more beyond the bases of design, the design of a new lighting system required of emergency in the Almaraz Nuclear power plant. The design process consists of three phases: study of needs, definition of detailed design and requirements. During these phases is defined distribution and models luminaire lighting studies and specifications. Through the adaptation of the system to the needs of each area of the plant is It achieves compliance with the objectives defined by the CSN. (Author)

Mejoramiento de imágenes usando funciones de base radial Images improvement using radial basis functions

Directory of Open Access Journals (Sweden)

Jaime Alberto Echeverri Arias

2009-07-01

Full Text Available La eliminación del ruido impulsivo es un problema clásico del procesado no lineal para el mejoramiento de imágenes y las funciones de base radial de soporte global son útiles para enfrentarlo. Este trabajo presenta una técnica de interpolación que disminuye eficientemente el ruido impulsivo en imágenes, mediante el uso de interpolante obtenido por funciones de base radial en el marco de la investigación enfocada en el desarrollo de un Sistema de recuperación de imágenes de recursos acuáticos amazónicos. Esta técnica primero etiqueta los píxeles de la imagen que son ruidosos y, mediante la interpolación, genera un valor de reconstrucción de dicho píxel usando sus vecinos. Los resultados obtenidos son comparables y muchas veces mejores que otras técnicas ya publicadas y reconocidas. Según el análisis de resultados, se puede aplicar a imágenes con altas tasas de ruido, manteniendo un bajo error de reconstrucción de los píxeles "ruidosos", así como la calidad visual.Global support radial base functions are effective in eliminating impulsive noise in non-linear processing. This paper introduces an interpolation technique which efficiently reduces image impulsive noise by means of an interpolant obtained through radial base functions. These functions have been used in a research project designed to develop a system for the recovery of images of Amazonian aquatic resources. This technique starts with the tagging by interpolation of noisy image pixels. Thus, a value of reconstruction for the noisy pixels is generated using neighboring pixels. The results obtained with this technique have proved comparable and often better than those obtained with previously known techniques. According to results analysis, this technique can be successfully applied on images with high noise levels. The results are low error in noisy pixel reconstruction and better visual quality.

Aptitud combinatoria general y especifica de líneas tropicales de maiz usando probadores

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Mauro Sierra

2000-01-01

Full Text Available Aptitud combinatoria general y específica de líneas tropicales de maíz usando probadores. Durante el ciclo O - I 1996/97 fueron evaluados en el Campo Experimental Cotaxtla mestizos de líneas sobresalientes y provenientes de varias fuentes de germoplasma como son : a Líneas recicladas de H-513 X VS-536, b Líneas derivadas de un compuesto de amplia base genética, c Líneas élite de programa de maíz de Cotaxtla (LTs y d Líneas de CIMMYT (CMLs. Como probadores se usaron las líneas LT-154 y LT-155 progenitores del híbrido H-513 y las líneas CML247 y CML254 cuya cruza es un patrón heterótico definido por CIMMYT para el trópico. Hubo líneas con buen comportamiento per-se tanto en rendimiento como en características agronómicas y que se encuentran formando mestizos sobresalientes con uno o varios probadores. Con relación a la Aptitud combinatoria, se encontró que las líneas F31XF30-4-3-1, F41XF40-1-2-1, CABG3’-12-2-1-2-1-1, LT174 y CML15 registraron los máximos valores con el probador 2 (LT155; F4XF3-5-2-1 y CML15 con el probador 4 (CMl254. Así también, las líneas F4XF5-5-1-1, y CABG3’-12-2-1-2-1-1, LT174, CML13 y CML15 con buena ACG. Con relación a los probadores, se encontró que para el grupo de líneas Recicladas , los probadores 1(LT154 y 4 (CML254 registraron los coeficientes de regresión más altos, lo que indica que permiten identificar líneas sobresalientes. Para líneas CABG fué el probador 2 (LT155 el que registró el mejor valor y en líneas Élite , los probadores 2(LT155, y 3(CML247 identificaron mejor a las líneas sobresalientes. Para las líneas del CIMMYT el mejor valor fué para el probador 4(CML254

The Combined Utility of a Brief Functional Measure and Performance-Based Screening Test for Case Finding of Cognitive Impairment in Primary Healthcare.

Science.gov (United States)

Chan, Qun Lin; Shaik, Muhammad Amin; Xu, Jing; Xu, Xin; Chen, Christopher Li-Hsian; Dong, YanHong

2016-04-01

Use of a total risk score (TRS) based on vascular and sociodemographic risk factors has been recommended to identify patients at risk of cognitive impairment. Moreover, combining screening tests has been reported to improve positive predictive values (PPV) for case finding of cognitive impairment. We investigated the utility of the conjunctive combination of the informant-based AD8 and the performance-based National Institute of Neurological Disorders and Stroke-Canadian Stroke Network (NINDS-CSN) 5-minute protocol for the detection of cognitive impairment, defined by a clinical dementia rating (CDR) score ≥0.5, in patients at risk of cognitive impairment (TRS ≥3). Participants were recruited from 2 primary healthcare centers in Singapore and received the AD8, Montreal Cognitive Assessment, Mini-Mental State Examination, CDR, and a formal neuropsychological test battery. The scores for NINDS-CSN 5-minute protocol were extracted from the Montreal Cognitive Assessment items. Area under the receiver operating characteristics curve analyses were conducted to determine the discriminant indices of the screening instruments, the conjunctive combination (ie, screened positive on both tests), and the compensatory combination (ie, screened positive in either of or both tests). A total of 309 participants were recruited of whom 78.7% (n = 243) had CDR = 0 and 21.3% (n = 66) had CDR ≥0.5. The conjunctive combination of AD8 and NINDS-CSN 5-minute protocol achieved excellent PPV and acceptable sensitivity (PPV 91.7%, sensitivity 73.3%). The conjunctive combination of the AD8 and NINDS-CSN 5-minute protocol is brief and accurate, and hence, suitable for case finding of cognitive impairment (CDR ≥0.5) in patients screened positive on the TRS in primary healthcare centers. Copyright © 2016. Published by Elsevier Inc.

Os efeitos da política monetária sobre o produto no Brasil: evidência empírica usando restrição de sinais

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Jocildo Fernandes Bezerra

2014-08-01

Full Text Available O presente trabalho tem por objetivo examinar os efeitos dos choques da política monetária sobre o Produto Interno Bruto (PIB e sobre a produção industrial, usando, respectivamente, dados de periodicidades trimestral e mensal, cobrindo o período de 1995 a 2010. O método empregado foi o de Vetores Autorregressivos (VAR, tal como proposto por Uhlig (2005, que consiste em permitir que as dinâmicas do PIB e do produto industrial se ajustem livremente às restrições dos sinais das funções de impulso-resposta das demais variáveis do modelo. Os resultados obtidos revelam que choques na taxa de juros da política monetária produzem efeitos mais expressivos quando comparados com estudos anteriores. A decomposição histórica da variância mostra que os choques mantêm o PIB abaixo de sua tendência no período de 1996 a 2002, enquanto no caso do produto industrial, esse padrão ocorre em todo o período estudado.

As to achieve regulatory action, regulatory approaches

International Nuclear Information System (INIS)

Cid, R.; Encinas, D.

2014-01-01

The achievement of the effectiveness in the performance of a nuclear regulatory body has been a permanent challenge in the recent history of nuclear regulation. In the post-Fukushima era this challenge is even more important. This article addresses the subject from two complementary points of view: the characteristics of an effective regulatory body and the regulatory approaches. This work is based on the most recent studies carried out by the Committee on Nuclear Regulatory Activities, CNRA (OECD/NEA), as well as on the experience of the Consejo de Seguridad Nuclear, CSN, the Spanish regulatory body. Rafael Cid is the representative of CSN in these project: Diego Encinas has participated in the study on regulatory approaches. (Author)

Establishing a national knowledge translation and generation network in kidney disease: the CAnadian KidNey KNowledge TraNslation and GEneration NeTwork.

Science.gov (United States)

Manns, Braden; Barrett, Brendan; Evans, Michael; Garg, Amit; Hemmelgarn, Brenda; Kappel, Joanne; Klarenbach, Scott; Madore, Francois; Parfrey, Patrick; Samuel, Susan; Soroka, Steven; Suri, Rita; Tonelli, Marcello; Wald, Ron; Walsh, Michael; Zappitelli, Michael

2014-01-01

Patients with chronic kidney disease (CKD) do not always receive care consistent with guidelines, in part due to complexities in CKD management, lack of randomized trial data to inform care, and a failure to disseminate best practice. At a 2007 conference of key Canadian stakeholders in kidney disease, attendees noted that the impact of Canadian Society of Nephrology (CSN) guidelines was attenuated given limited formal linkages between the CSN Clinical Practice Guidelines Group, kidney researchers, decision makers and knowledge users, and that further knowledge was required to guide care in patients with kidney disease. The idea for the Canadian Kidney Knowledge Translation and Generation Network (CANN-NET) developed from this meeting. CANN-NET is a pan-Canadian network established in partnership with CSN, the Kidney Foundation of Canada and other professional societies to improve the care and outcomes of patients with and at risk for kidney disease. The initial priority areas for knowledge translation include improving optimal timing of dialysis initiation, and increasing the appropriate use of home dialysis. Given the urgent need for new knowledge, CANN-NET has also brought together a national group of experienced Canadian researchers to address knowledge gaps by encouraging and supporting multicentre randomized trials in priority areas, including management of cardiovascular disease in patients with kidney failure.

Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4–signalosome complex to regulate DNA repair and cell death

Science.gov (United States)

Rao, Feng; Xu, Jing; Khan, A. Basit; Gadalla, Moataz M.; Cha, Jiyoung Y.; Xu, Risheng; Tyagi, Richa; Dang, Yongjun; Chakraborty, Anutosh; Snyder, Solomon H.

2014-01-01

Inositol polyphosphates containing an energetic pyrophosphate bond are formed primarily by a family of three inositol hexakisphosphate (IP6) kinases (IP6K1–3). The Cullin-RING ubiquitin ligases (CRLs) regulate diverse biological processes through substrate ubiquitylation. CRL4, comprising the scaffold Cullin 4A/B, the E2-interacting Roc1/2, and the adaptor protein damage-specific DNA-binding protein 1, is activated by DNA damage. Basal CRL4 activity is inhibited by binding to the COP9 signalosome (CSN). UV radiation and other stressors dissociate the complex, leading to E3 ligase activation, but signaling events that trigger signalosome dissociation from CRL4 have been unclear. In the present study, we show that, under basal conditions, IP6K1 forms a ternary complex with CSN and CRL4 in which IP6K1 and CRL4 are inactive. UV dissociates IP6K1 to generate IP7, which then dissociates CSN–CRL4 to activate CRL4. Thus, IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4–CSN complex, thereby regulating nucleotide excision repair and cell death. PMID:25349427

GPE-BWR and the containment venting and filtering issue

International Nuclear Information System (INIS)

Palomo, J.; Santiago, J. de

1988-01-01

The Spanish Boiling Water Reactor Owner's Group (GPE-BWR) is formed by three utilities, owning four units: Santa Maria de Garona (46 MWe, BWR3, Mark I containment), Cofrentes (975 MWe, BWR6, Mark III containment) and Valdecaballeros (2x975 MWe, BWR6, Mark III containment) - all of the reactors having been supplied by General Electric. One of the GPE-BWR's several committees is the Safety and Licensing Committee, which follows up the evolution of severe accident topics and particularly the containment venting and filtering issue. In September 1987, the Consejo de Seguridad Nuclear (CSN), the Spanish Regulatory Body, asked the GPE-BWR to define its position on the installation of a containment venting system. The GPE-BWR created a Working Group which presented a Report on Containment Venting to the CSN in January 1987 gathered from: the US Nuclear Regulatory Commission (NRC); some US utilities; and several European countries, especially France, Germany and Sweden. CSN's review of the containment venting Report and the Action Plan proposed by the GPE-BWR finished in April 1988. The conclusion of the Report and the proposed Action Plan take into account the US NRC's identified open items on severe accidents and the R and D programs scheduled to close these items

ALGUNAS HERRAMIENTAS PARA LA TOMA DE DECISIONES DE INVERSIÓN EN PROYECTOS DE ALTO RIESGO

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Julio Villarreal

2007-01-01

Full Text Available En este trabajo se presenta un posible aplicación metodológica para la toma de decisiones de inversión en proyectos de alto riesgo como las que típicamente son apoyados por los llamados fondos de capital de riesgo. El objetivo final es mostrar como es posible a través de esta metodología, reducir las asimetrías de información típicas en la relación entre inversionistas de riesgo (accionistas de capital y gestores de proyectos (accionistas industriales. La metodología propuesta se aplica a un plan de negocios real, pero de igual manera se puede aplicar a otros proyectos riesgosos, y muestra cómo una adecuada estructuración de un proceso de decisión, usando los modelos y herramientas adecuadas puede ser muy útil tanto en decisiones de fondos de inversión como en la estructuración de procesos de evaluación de alternativas de decisión estratégicas en las que el riesgo hace inapropiado el tradicional análisis determinístico.

Implementación de un control fuzzy para el control cinemático directo en un robot manipulador Implementation of a fuzzy control for the direct kinematic control of a robot manipulator

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D.A Tibaduiza

2011-12-01

Full Text Available En este artículo se muestra el desarrollo e implementación de la lógica difusa como herramienta de control de posición para cada una de las articulaciones de un robot tipo PUMA. Se hace una descripción general del robot y se muestra el cálculo del volumen de trabajo, el cual es usado para la fuzzificación en el desarrollo del controlador. Finalmente es mostrado el desarrollo y la simulación del controlador usando la toolbox fuzzy de Matlab, así como la descripción de una implementación realizada en un PLC.In this article, the development and implementation of a fuzzy logic system as position control tool of each one of the joints in a PUMA robot is shown. A general description, which include general descriptions about the robot as workspace and therefore the development of the strategy of control with the definition of the rules in the fuzzification process is also included. Finally are shown the development and simulation of the controller using the fuzzy control toolbox of Matlab and the description of a implementation in a PLC.

Energy expenditures & physical activity in rats with chronic suboptimal nutrition.

Science.gov (United States)

Rising, Russell; Lifshitz, Fima

2006-01-31

Sub-optimally nourished rats show reduced growth, biochemical and physiological changes. However, no one has assessed metabolic rate adaptations in rats subjected to chronic suboptimal nutrition (CSN). In this study energy expenditure (EE; kcal/100 g body weight) and physical activity (PA; oscillations in weight/min/kg body weight) were assessed in rats subjected to three levels of CSN. Body weight gain was diminished (76.7 +/- 12.0 and 61.6 +/- 11.0 g) in rats fed 70 and 60% of the ad-libitum fed controls which gained more weight (148.5 +/- 32.3 g). The rats fed 80% gained weight similarly to controls (136.3 +/- 10.5 g). Percent Fat-free body mass was reduced (143.8 +/- 8.7 and 142.0 +/- 7.6 g) in rats fed 70 and 60% of ad-libitum, but not in those fed 80% (200.8 +/- 17.5 g) as compared with controls (201.6 +/- 33.4 g). Body fat (g) decreased in rats fed 80% (19.7 +/- 5.3), 70% (15.3 +/- 3.5) and 60% (9.6 +/- 2.7) of ad-libitum in comparison to controls (26.0 +/- 6.7). EE and PA were also altered by CSN. The control rats increased their EE and PA during the dark periods by 1.4 +/- 0.8 and 1.7 +/- 1.1 respectively, as compared with light the period; whereas CSN rats fed 80 and 70% of ad-libitum energy intake had reduced EE and PA during the dark periods as compared with the light period EE(7.5 +/- 1.4 and 7.8 +/- 0.6 vs. 9.0 +/- 1.2 and 9.7 +/- 0.8; p vs. 4.1 +/- 0.9 and 2.4 +/- 0.4; p vs. 0.95 +/- 0.03 and 0.91 +/- 0.05 p light (7.1 +/- 1.4) and dark period (6.2 +/- 1.0) EE and PA (3.4 +/- 0.9 and 2.5 +/- 0.5 respectively) were reduced in rats fed 60% of ad-libitum energy intake. CSN rats adapt to mild energy restriction by reducing body fat, EE and PA mainly during the dark period while growth proceeds and lean body mass is preserved. At higher levels of energy restrictions there is decreased growth, body fat and lean mass. Moreover EE and PA are also reduced during both light and dark periods.

Development of a simple computer code to obtain relevant data on H2 and CO combustion in severe accidents and to aid in PSA-2 assessments

International Nuclear Information System (INIS)

Robledo, F.; Martin-Valdepenas, J.M.; Jimenez, M.A.; Martin-Fuertes, F.

2007-01-01

By following Consejo de Seguridad Nuclear (CSN) requirements, all of the Spanish NPPs performed plant specific PSA level 2 studies and implemented Severe Accident Management Guidelines during the first years of this century. CSN and contractors made an independent detailed review of these PSA level 2 studies. This independent review included the performance of plant specific calculations by using the MELCOR code and some other stand-alone codes and the calculation of the fission product release frequencies for each plant. One of the aspects treated in detail by CSN evaluations was the calculation of the containment failure probability due to the burn of combustible gases generated during a severe accident. It was shown that it would be useful to have a fast running code with capability to provide the most relevant data concerning H 2 and CO combustion. Therefore, the Polytechnic University of Madrid (UPM) developed the CPPC code for the CSN. This stand-alone module makes fast calculations on maximum static pressures in the containment building generated from H 2 and CO combustion in severe accidents, considering well-mixed atmospheres and includes the most recent advances and developments in the field of H 2 and CO combustion. Code input is simple: mass of H 2 and CO, initial environmental conditions inside the containment before the combustion and simple geometric data, such as the volume of the building enclosing the combustible gases. The code calculates the containment temperature assuming steam saturated atmosphere and provides the following output: - Combustion completeness (CC); - Adiabatic and isochoric combustion pressure (p AICC ); - Chapman-Jouguet pressure (p CJ ); - Chapman-Jouguet reflected pressure (p Cjrefl ). When the combustion regime results in dynamic pressure loads, the CPPC code calculates the equivalent static pressure (effective pressure p eff ) by modeling the containment structure as a simple harmonic oscillator. Additionally, the code

A new approach to incorporate operator actions in the simulation of accident sequences

International Nuclear Information System (INIS)

Antonio Exposito; Juan Antonio Quiroga; Javier Hortal; John-Einar Hulsund

2006-01-01

Full text of publication follows: Nowadays, simulation-based human reliability analysis (HRA) methods seem to provide a new direction for the development of advanced methodologies to study operator actions effect during accident sequences. Due to this, the Spanish Nuclear Safety Council (CSN) started a working group which has, among other objectives, to develop such simulation-based HRA methodology. As a result of its activities, a new methodology, named Integrated Safety Assessment (ISA), has been developed and is currently being incorporated into licensing activities at CSN. One of the key aspects of this approach is the incorporation of the capability to simulate operator actions, expanding the ISA methodology scopes to make HRA studies. For this reason, CSN is involved in several activities oriented to develop a new tool, which must be able to incorporate operator actions in conventional thermohydraulic (TH) simulations. One of them is the collaboration project between CSN, Halden Reactor Project (HRP) and the Department of Energy Systems (DSE) of the Polytechnic University of Madrid that started in 2003. The basic aim of the project is to develop a software tool that consists of a closed-loop plant/operator simulator, a thermal hydraulic (TH) code for simulating the plant transient and the procedures processor to give the information related with operator actions to the TH code, both coupled by a data communication system which allows the information exchange. For the plant simulation we have a plant transient simulator code (TRETA/TIZONA for PWR/BWR NPPs respectively), developed by the CSN, with PWR/BWR full scope models. The functionality of these thermalhydraulic codes has been expanded, allowing control the overall information flow between coupled codes, simulating the TH transient and determining when the operator actions must be considered. In the other hand, we have the COPMA-III code, a computerized procedure system able to manage XML operational

Terapia baseada em realidade virtual usando o leap motion controller para reabilitação do membro superior após acidente vascular cerebral = Virtual reality therapy using the leap motion controller for post-stroke upper limb rehabilitation Virtual reality therapy using the Leap Motion Controller for post-stroke upper limb rehabilitation

Directory of Open Access Journals (Sweden)

Soares, Nayron Medeiros

2017-01-01

Full Text Available OBJETIVOS: Avaliar a aplicabilidade de um sensor de movimento, baseado em realidade virtual, para promover a reabilitação do membro superior após um acidente vascular cerebral. RELATO DOS CASOS: Três pacientes após acidente vascular cerebral realizaram um treino para reabilitação do membro superior com realidade virtual usando a tecnologia Leap Motion Controller e o jogo Playground 3D®, durante três dias consecutivos. No primeiro e no terceiro dia, foram avaliados com os testes Caixa e Blocos, Coordenação Óculo-Manual de Melo e Estimulação Magnética Transcraniana. No último dia, foram aplicadas Fichas de Avaliação da Experiência do paciente. Após o treinamento proposto, observou-se diminuição do limiar motor em ambos os hemisférios cerebrais e melhores desempenhos nos testes que avaliaram a habilidade manual e óculo-manual. A terapia proposta foi bem recebida pelos pacientes testados. CONCLUSÕES: Não foram observados efeitos adversos e os resultados mostram-se promissores e precisos no treinamento realizado com realidade virtual usando a tecnologia Leap Motion Controller e o jogo Playground 3D®. O treinamento proporcionou uma participação ativa dos pacientes na reabilitação das sequelas de extremidade superior após um acidente vascular cerebral

Seismic margin assessment of spanish nuclear power plants: a perspective from industry and regulators

International Nuclear Information System (INIS)

Garcia-Monge, Juan; Beltran, Francisco; Sanchez-Cabanero, Jose G.

2001-01-01

The worldwide experience with probabilistic safety analysis (PSA) of nuclear power plants shows that the risk derived from earthquakes can be a significant contributor to core damage frequency in some instances. As a consequence, no severe accident safety assessment can be considered complete without giving, due consideration to seismic risk. This fact has been recognized by some regulators. in particular, by the U.S. Nuclear Regulatory Commission (NRC), who has included seismic risk assessment in its severe accident policy. The NRC severe accident policy was adopted by the Spanish nuclear regulator. the Consejo de Seguridad Nuclear (CSN). As a result. all plants in Spain were asked to perform a seismic risk analysis according to Supplements No. 4 and 5 of Generic Letter 88-20 and NUREG-1407, which included the containment failure analysis. At present in Spain there arc nine operating reactors at seven sites: six Westinghouse-PWR, two GE-BWR and one Siemens/KW U-PWR. The vintages are very different: the oldest plant started commercial operation in 1968 and the most recent, in 1988. In this framework, the Spanish Owners Group (SOG) proposed to CSN in 1994 to carry out the seismic risk analysis of the plants using seismic margin methodologies. This kind of methods requires, as a starting point, the definition of a seismic margin earthquake (SNIE), also called review level earthquake (RLL). For this purpose, tile SOG sponsored a general Probabilistic Seismic Hazard Analysis (PSHA) for the seven Spanish sites. The results of this PSHA were used by the SOG to define tile RLE and the scope of the study for each plant (binning of plants). The proposal was submitted to the CSN for evaluation. The CSN evaluation was based on the NRC practical experience and was helped by the technical advise of US Lawrence Livermore National Laboratory. The review showed that the uncertainties on seismic hazard had not been fully captured and that it would have been justified to consider a

The theory of the regulatory bodies and the CSN; La teoria de las entidades reguladoras y el CSN

Energy Technology Data Exchange (ETDEWEB)

Gamir Casares, L.

2011-07-01

In this article the vice president of the Nuclear Safety Council and professor of Economics and Politics, Luis Gamir, analyses the theoretical nature of the role played by regulatory organisations in democratic societies and the keys of their credibility, with special reference to the Council and the Strategic Plan recently approved for the period 2011-2016. (Author)

Análisis del tratamiento ideal usando baños termotratados para la separación de cal de los residuos de descarne en curtiembres

Directory of Open Access Journals (Sweden)

Yelitza Aguas Mendoza

2016-07-01

Full Text Available Se analizó el tratamiento ideal usando baños termotratados para la separación de cal de los residuos de descarne, del proceso de curtición semiartesanal desarrollado en Sampués, Departamento de Sucre (Colombia. Para su desarrollo se seleccionó una muestra de carnaza representativa, homogénea y con menos tiempo de almacenamiento. Dicha muestra se redujo al tamaño de 1 cm2 y se conservó refrigerada para posteriormente realizar los análisis de grasa, pH y presencia de cal. Los baños termotratados de desencalado se realizaron a tres temperaturas diferentes (26, 30 y 35 ºC. Se utilizó como agente desencalante el acido sulfúrico en tres concentraciones (3, 2 y 1 N. Además se usó un sistema de agitación simulando el bombo en proceso industrial. Se llevaron a cabo nueve pruebas con tres repeticiones para mayor confiabilidad de los datos, en donde se determinó la correlación existente entre las variables independientes, temperatura y concentración, sobre la cal impregnada y los resultados de grasa en cada una de las muestras en un tiempo de 4 y 8 h.

Infecção cirúrgica em colecistectomia videolaparoscópica usando ácido peracético como esterilizante dos instrumentais

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Edluza Maria Viana Bezerra de Melo

Full Text Available OBJETIVO: Determinar a frequência de infecção de sítio cirúrgico em pacientes submetidos à colecistectomia videolaparoscópica usando o ácido peracético como esterilizante. MÉTODOS: Foi realizado estudo retrospectivo descritivo do tipo coorte transversal. O ácido peracético foi usado para esterilização seguindo protocolo preconizado pelo fabricante. Foram observados os critérios e indicadores de processo e estrutura para prevenção de infecção de sítio cirúrgico no pré e intraoperatório. Para a vigilância epidemiológica, consultas ambulatoriais eram agendadas para o 15º e entre o 30º e 45º dias após a alta. RESULTADOS: Entre 247 pacientes foram diagnosticados dois casos de infecção de sítio cirúrgico (0,8%. Um paciente reinternou para antibioticoterapia sistêmica e punção percutânea; no outro, a infecção foi superficial e acompanhada ambulatorialmente. CONCLUSÃO: Eticamente não é permitida a realização de um estudo prospectivo pelo fato do ácido peracético ter sido proibido para a esterilização de instrumentais que penetrem em órgãos e cavidades; contudo, estes resultados encorajam estudo prospectivo caso-controle, comparando o uso dele (controle histórico com a esterilização por óxido de etileno.

Discriminación de coberturas del suelo usando datos espectrales multi-angulares del sensor polder-1: alcances y limitaciones

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Fernando Paz Pellat

2016-04-01

Full Text Available La información espectral multi-angular (visión de un píxel desde diferentes ángulos de visión y con ángulos de iluminación solar diferentes obtenida de sensores remotos tiene potencial para una discriminación adecuada de clases de coberturas del suelo. De acuerdo con varios esfuerzos realizados para poder analizar la capacidad de discriminación de las clases de cobertura del suelo, se introduce un marco teórico-conceptual para el análisis de la información espectral, angular y temporal (tamaño de píxel fijo. En este trabajo se explora el uso del sensor POLDER-1. La base de datos fue analizada ajustando un modelo de la función de distribución bidireccional de las reflectancias (BRDF en las bandas espectrales disponibles, para diferentes clases de cobertura del suelo del sistema GLC2000. Los resultados experimentales muestran adecuados ajustes a nivel de píxeles y datos diarios. Con los parámetros ajustados del modelo de la BRDF se analizó el potencial de discriminación usando espacios espectrales de las bandas de la región del rojo e infrarrojo cercano, utilizando diferentes resoluciones temporales y espaciales (agrupación de píxeles. Los resultados mostraron alta confusión (traslapes de posición en espacios espectrales, detectándose limitaciones de dichos enfoques para el caso de confusiones debidas a mezclas de clases o causadas por la dinámica temporal de las mismas. Al final se define un esquema para aproximar la clasificación de la vegetación al acoplar la información disponible en los sensores ópticos y las clases que pueden ser discriminadas.

¿El proceso de enfermería hace parte de la calidad del cuidado? Is the nursing process part of quality care?

Directory of Open Access Journals (Sweden)

MYRIAM ABAUNZA DE GONZÁLEZ

2007-12-01

Full Text Available El principal propósito de este artículo es dar respuesta al siguiente interrogante: ¿El proceso de enfermería hace parte de la calidad del cuidado? Para sustentar la respuesta a la pregunta, se parte de referenciar varios autores que han hecho estudios sobre la utilización del método científico, del método de solución de problemas y del proceso de atención de enfermería y su relación con la calidad del servicio y del cuidado de enfermería, al mismo tiempo que se introducen experiencias relacionadas con proyectos de investigación tipo NIPE y Grupos relacionados con el Dx, y experiencias de evaluación de servicios de enfermería en algunos hogares y hospitales en Colombia, México, Cuba y Chile, en donde se aprecia que el proceso de enfermería es el que define el concepto enfermero aplicado. Se concluye que el proceso de enfermería como parte fundamental del cuidado de enfermería, al acortar estancias, disminuir el número de complicaciones y evitar los reingresos, contribuye a mejorar la calidad de su servicio y la calidad de vida de los pacientes/usuarios.The main purpose of this article is to answer the question: Is the nursing process part of quality care? In order to back the answer, it starts by mentioning several authors that have performed studies on the use of scientific methods, problem solving methods and the attention to care -innursing method and its relationship to the quality of service and the nursing care, while at the same time it introduces related experiences associated with NIPE research projects and related Groups with Dx, and evaluation experiences for nursing services in various homes and hospitals in Colombia, México, Cuba and Chile. There, one can appreciate that the nursing process is that which is defined by the concept of applied nurse. It concludes that by saying that the nursing process is fundamental to nursing care, because it shortens distances, reduces the number of complications and avoids

Is the nursing process part of quality care? ¿El proceso de enfermería hace parte de la calidad del cuidado?

Directory of Open Access Journals (Sweden)

ABAUNZA DE GONZÁLEZ MYRIAM

2007-12-01

Full Text Available The main purpose of this article is to answer the question: Is the nursing process part of quality care? In order to back the answer, it starts by mentioning several authors that have performed studies on the use of scientific methods, problem solving methods and the attention to care -innursing method and its relationship to the quality of service and the nursing care, while at the same time it introduces related experiences associated with NIPE research projects and related Groups with Dx, and evaluation experiences for nursing services in various homes and hospitals in Colombia, México, Cuba and Chile. There, one can appreciate that the nursing process is that which is defined by the concept of applied nurse. It concludes that by saying that the nursing process is fundamental to nursing care, because it shortens distances, reduces the number of complications and avoids risks, while contributing to improve the quality of service and the quality of life of patients /users.El principal propósito de este artículo es dar respuesta al siguiente interrogante: ¿El proceso de enfermería hace parte de la calidad del cuidado? Para sustentar la respuesta a la pregunta, se parte de referenciar varios autores que han hecho estudios sobre la utilización del método científico, del método de solución de problemas y del proceso de atención de enfermería y su relación con la calidad del servicio y del cuidado de enfermería, al mismo tiempo que se introducen experiencias relacionadas con proyectos de investigación tipo NIPE y Grupos relacionados con el Dx, y experiencias de evaluación de servicios de enfermería en algunos hogares y hospitales en Colombia, México, Cuba y Chile, en donde se aprecia que el proceso de enfermería es el que define el concepto enfermero aplicado. Se concluye que el proceso de enfermería como parte fundamental del cuidado de enfermería, al acortar estancias, disminuir el número de complicaciones y evitar los

The antifungal efficiency of carbide lime slurry compared with the commercial lime efficiency

Science.gov (United States)

Strigac, J.; Mikusinec, J.; Strigacova, J.; Stevulova, N.

2017-10-01

The article deals with studying the antifungal efficiency of carbide lime slurry compared to industrially manufactured commercial lime. Antifungal efficiency expressed as mould proofness properties was tested on the fungi using the procedure given in standard CSN 72 4310. A mixture of fungi Aspergillus niger, Chaetomium globosum, Penicillium funiculosum, Paecilomyces variotii and Gliocladium virens was utilized for testing. The scale for evaluating mould proofness properties according to CSN 72 4310 is from 0 to 5 in degree of fungi growth, where 0 means that no fungi growth occurs and the building products and materials possess fungistatic properties. The study confirms the fungistatic propeties of carbide lime slurry as well as industrially manufactured commercial lime. However, carbide lime slurry and industrially manufactured commercial lime possess no fungicidal effect.

Safety Harmonization of Nuclear Reactors in Europe; La armonizacion de la seguridad de los reactores nucleares en Europa

Energy Technology Data Exchange (ETDEWEB)

Estevan Bolea, M. T.

2006-07-01

Dialogue and common tasks over the past few years have intensified among high level figures responsible for regulation organizations involved in nuclear installations from European countries as well as others. The best indicator of this is the harmonization of safety levels for european nuclear reactors. The CSN increasingly participates more intensely in three relevant international associations on these matters: INRA, FORO IBEROAMERICANO and WENDA. A detail study has been carried out by a WENRA work group whose results represent a large contribution made toward harmonization at reference levels on reactor safety issues, both from a legal viewpoint, and for their implantation in nuclear power plants. The President of the CSN explains in detail the most relevant aspects of this Final Report from WENRA. (Author)

La Incidencia de los Estilos de Aprendizaje en el Aprendizaje de las Matemáticas usando Recursos Educativos Abiertos (REA) en los Estudiantes de 4to. y 5to. de Primaria de la Escuela Rural Mercadillo, municipio de Pandi, Cundinamarca, Colombia.

OpenAIRE

Ortiz Cañon, Edison L.

2016-01-01

La sociedad actual se ve influenciada fuertemente por los avances tecnológicos, que han venido incursionando de manera gradual en el ámbito educativo provocando cambios significativos en el rol del docente y del estudiante, lo cual hace necesario que permanentemente se estén innovando las estrategias de enseñanza-aprendizaje, para lograr mejores resultados académicos. Además se requiere que frecuentemente se investigue y se evalué la influencia de estos recursos en la educación, de esta forma...

Effects of Genotypes on Economic Traits in Chinese Dairy Goats

Directory of Open Access Journals (Sweden)

X. P. Yue

2013-07-01

Full Text Available The aim of this study was to investigate allele frequencies at the CSN1S2 locus in two Chinese dairy goat breeds and the effects of its variation on dairy goat economic traits. Seven hundred and eight goats from Xinong Saanen (XS, n = 268 and Guanzhong (GZ, N = 440 breeds were selected. The milk samples of 268 XS goats were collected during the middle of lactation, body size parameters (708 goats and daily milk yield (202 goats were registered. The RFLP (restriction fragment length polymorphism and SSCP (single strand conformation polymorphism were used to detect the polymorphisms in CSN1S2. The Hardy-Weinberg (HW equilibrium and the associations between body size, milk yield and composition and the genotypes were calculated. The results revealed that only A and F CSN1S2 alleles were found in the two Chinese dairy goat breeds. Allelic frequencies of A and F were 0.795, 0.205 and 0.739, 0.261 in Xinong Saanen and Guanzhong population respectively. Xinong Saanen breed was in Hardy-Weinberg equilibrium, while Guanzhong breed deviated from Hardy-Weinberg equilibrium (p<0.05. The association of polymorphism with economic traits indicated that the goats with FF genotype have higher milk fat and total solid concentration than those with AA and AF genotypes (p<0.05.

Establishing a National Knowledge Translation and Generation Network in Kidney Disease: The CAnadian KidNey KNowledge TraNslation and GEneration NeTwork

Directory of Open Access Journals (Sweden)

Braden Manns

2014-04-01

Full Text Available Patients with chronic kidney disease (CKD do not always receive care consistent with guidelines, in part due to complexities in CKD management, lack of randomized trial data to inform care, and a failure to disseminate best practice. At a 2007 conference of key Canadian stakeholders in kidney disease, attendees noted that the impact of Canadian Society of Nephrology (CSN guidelines was attenuated given limited formal linkages between the CSN Clinical Practice Guidelines Group, kidney researchers, decision makers and knowledge users, and that further knowledge was required to guide care in patients with kidney disease. The idea for the Canadian Kidney Knowledge Translation and Generation Network (CANN-NET developed from this meeting. CANN-NET is a pan-Canadian network established in partnership with CSN, the Kidney Foundation of Canada and other professional societies to improve the care and outcomes of patients with and at risk for kidney disease. The initial priority areas for knowledge translation include improving optimal timing of dialysis initiation, and increasing the appropriate use of home dialysis. Given the urgent need for new knowledge, CANN-NET has also brought together a national group of experienced Canadian researchers to address knowledge gaps by encouraging and supporting multicentre randomized trials in priority areas, including management of cardiovascular disease in patients with kidney failure.

Identificação de variáveis cataclísmicas eruptivas na direção do bojo galáctico e Nuvens de Magalhães usando dados do OGLE

Science.gov (United States)

Cieslinski, D.; Diaz, M. P.; Mennickent, R.; Pietrzyski, G.

2003-08-01

Na década de 90 iniciaram-se vários programas para a pesquisa de matéria escura na Galáxia usando o efeito de microlentes gravitacionais. Entre os projetos mais bem conhecidos podemos mencionar o OGLE (Optical Gravitational Lensing Experiment) e o MACHO (MAssive Compact Halo Objects). A estratégia usada por eles consiste em fazer fotometria de banda larga (normalmente B, R e I) de um grande número de estrelas (dezenas de milhões) tão freqüentemente quanto possí vel e por longos perí odos de tempo (anos). Uma tal sistemática de observação, além de descobrir inúmeras lentes gravitacionais, é também muito apropriada para a descoberta de estrelas variáveis. De fato, inúmeras novas variáveis de vários tipos foram descobertas como subproduto. Exemplos podem ser encontrados nos endereços http://bulge.princeton.edu/~ogle/ e http://wwwmacho.mcmaster.ca/. As variáveis cataclí smicas eruptivas (novas clássicas, novas recorrentes e novas anãs) são objetos que apresentam variabilidade de grande amplitude com escalas de tempo de dias a centenas de dias e, por esta razão, devem ter sido detectadas em grande número nestes "surveys". Para testar esta possibilidade nós procuramos nos dados do OGLE por tais sistemas e o presente trabalho mostra os resultados desta pesquisa. Os objetos foram selecionados entre as variáveis detectadas usando a amplitude de variação de brilho como critério principal. Este critério forneceu 13756 objetos, sendo 2169 na direção da Grande Nuvem de Magalhães, 1162 na direção da Pequena Nuvem de Magalhães e o restante na direção do Bojo Galáctico. A análise foi feita inspecionando-se visualmente cada curva de luz por erupções com as características acima mencionadas. Os resultados obtidos podem ser sumarizados como: descoberta de duas novas clássicas e 33 novas anãs. Além disso, pode-se mencionar a identificação de candidatas a outros tipos de variáveis como: estrelas simbióticas, RV Tauri, R Coronae

Variabilidad genética de Aedes aegypti en algunas áreas del Perú usando Single Stranded Conformational Polymorphism (SSCP

Directory of Open Access Journals (Sweden)

Nélida Leiva G

2004-07-01

Full Text Available Aedes aegypti es el vector responsable de la transmisión del virus del dengue, su distribución geográfica se ha ampliado rápidamente debido principalmente a la intervención de los seres humanos. Objetivo: Analizar la variabilidad genética de este mosquito mediante la comparación del Segundo Espaciador Transcrito Interno (ITS 2 perteneciente al ADN ribosomal (rADN. Materiales y Métodos: Se analizaron muestras de ocho localidades (Jaén, Tingo María, Iquitos, Lambayeque, el distrito de El Rimac, Sullana y Zarumilla y uno de la provincia de Huaquillas (Ecuador. El análisis de la variabilidad se determinó usando la técnica conocida como SSCP (Single Stranded Conformation Polymorphism. Resultados: El estudio muestra que existe variabilidad genética entre las poblaciones analizadas, principalmente entre las muestras localizadas en la costa del Perú (Zarumilla, El Rímac, Sullana y Huaquillas y las muestras del nororiente (Tingo María, Iquitos, Jaén y Lambayeque Conclusión: Se determinaron dos variantes genéticas entre las poblaciones de Aedes aegypti: Costeña y Nororiental, que probablemente provienen de dos ancestros diferentes y cuyo ancestro común sufrió de aislamiento por distancia. Se observó que no existe relación entre las distancias genéticas y las distancias geográficas indicando que la migración de estas poblaciones es el resultado de la intervención de los seres humanos que diseminan al vector y no por la migración activa del mosquito. Se plantea el papel de la Cordillera de los Andes en la migración y separación de las poblaciones de Aedes.

Control Activo de Vibraciones en un Rotor Tipo Jeffcott con Velocidad Variable Usando una Suspensión Electromecánica

Directory of Open Access Journals (Sweden)

F. Beltrán-Carbajal

2014-07-01

Full Text Available Resumen: En este trabajo se presenta un esquema de balanceo activo para un rotor tipo Jeffcott con velocidad variable, usando una suspensión con actuadores electromecánicos lineales. Se propone un esquema de estimación de las señales de perturbación que se inducen por la excentricidad presente en el sistema rotor-chumacera y una ley de control del desbalance que combina tareas de seguimiento de trayectorias para el perfil de velocidades en el rotor. Las señales de perturbación se estiman adecuadamente y el control de la velocidad se realiza en forma robusta, dando como resultado un desempeño eficiente del esquema de control activo para la supresión de vibraciones, con amplitud y frecuencia variables, generadas por el inherente desbalance desconocido en elrotor. Abstract: An active balancing scheme for a variable rotor speed Jeffcott-like rotor, using a suspension with linear electromechanical actuators, is presented. In addition, an estimation scheme for the perturbation signals induced by the inherent eccentricity on the rotating mechanical system, and a control law synthesized for simultaneous tracking tasks on the rotor speed are proposed. Some simulation results show the fast and efficient performance of the active vibration control scheme for good suppression of variable amplitude and frequency harmonic vibrations associated to the unbalance, as well as an effective estimation of the perturbation signals and robustness of the rotor speed controller. The proposed methodology can be applied for on-line monitoring and fault detection quite common in rotating machinery. Palabras clave: Control activo de vibraciones, Rotor tipo Jeffcott, Rechazo de perturbaciones., Keywords: Active vibration control, Jeffcott-like rotor, Disturbance rejection.

Controle dos vasos renais usando clips vasculares e fio cirúrgico em nefrectomias vídeo-assistidas de doadores vivos

Directory of Open Access Journals (Sweden)

Alcides José Branco Filho

Full Text Available OBJETIVO: A nefrectomia laparoscópica em doadores vivos para transplante renal vem assumindo um papel importante na era das cirurgias minimamente invasivas, acarretando menor morbidade aos doadores, e resultados semelhantes à técnica aberta no que se refere ao enxerto renal. O objetivo do presente artigo é relatar a experiência do nosso serviço utilizando a técnica de controle dos vasos renais usando fio cirúrgico e clips vasculares. MÉTODO: Foram realizadas 45 nefrectomias utilizando a técnica vídeo-assistida, com ligadura dos vasos renais com clips de titânio (LT-300 e fio cirúrgico. As variáveis analisadas foram tempo cirúrgico, perda sangüínea, tempo de isquemia quente, permanência hospitalar, necessidade de conversão e complicações. RESULTADOS: O procedimento foi realizado com sucesso em todos os casos. O tempo cirúrgico médio foi de 118 minutos, com perda sangüínea estimada em 84ml e tempo de isquemia quente de 4,3 minutos. Dois casos de íleo prolongado, uma lesão de veia gonadal, um escape de artéria renal e uma necrose de ureter foram observados. A permanência hospitalar média foi de 3,7 dias. O uso de clips vasculares e fio cirúrgico reduziu a perda de tecido venoso comparado à técnica com staplers e gerou redução de custos. CONCLUSÕES: A nefrectomia vídeo-assistida com a técnica descrita é factível e mostrou ser efetiva na contenção de gastos e na redução de tecido venoso perdido.

Evaluación termodinámica de sistemas de climatización centralizados por agua helada usando herramientas de inteligencia artificial

Directory of Open Access Journals (Sweden)

Juan Carlos Armas

2011-05-01

Full Text Available Se presenta el análisis de un sistema centralizado de climatización por agua helada con el objetivo de evaluar las irreversibilidades en los componentes principales del ciclo, así como la sensibilidad de este indicador ante las variaciones de las condiciones de operación. Se hace uso de redes neuronales artificiales (RNA y algoritmos genéticos (AG, herramientas de Matlab para  determinar las propiedades de los refrigerantes en cada punto del ciclo en estudio y que éstas, a su vez, interactúen con las ecuaciones que describen el comportamiento termodinámico del sistema. La temperatura del refrigerante a la salida del  compresor se determina a partir de un modelo híbrido que conjuga el modelo neuronal con un algoritmo genético simple como herramienta de optimización. Como resultado final se identifican  los componentes del ciclo más sensibles ante las variaciones de las condiciones de trabajo, se obtiene que el evaporador y el mecanismo de expansión, respectivamente, siguen al compresor con pérdidas exergéticas significativas, sumando entre todas 85,62% de las irreversibilidades totales del sistema, conformándose así una herramienta útil para la  evaluación de tales sistemas.

Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes.

Science.gov (United States)

Sacramento, Joana F; Chew, Daniel J; Melo, Bernardete F; Donegá, Matteo; Dopson, Wesley; Guarino, Maria P; Robinson, Alison; Prieto-Lloret, Jesus; Patel, Sonal; Holinski, Bradley J; Ramnarain, Nishan; Pikov, Victor; Famm, Kristoffer; Conde, Silvia V

2018-03-01

A new class of treatments termed bioelectronic medicines are now emerging that aim to target individual nerve fibres or specific brain circuits in pathological conditions to repair lost function and reinstate a healthy balance. Carotid sinus nerve (CSN) denervation has been shown to improve glucose homeostasis in insulin-resistant and glucose-intolerant rats; however, these positive effects from surgery appear to diminish over time and are heavily caveated by the severe adverse effects associated with permanent loss of chemosensory function. Herein we characterise the ability of a novel bioelectronic application, classified as kilohertz frequency alternating current (KHFAC) modulation, to suppress neural signals within the CSN of rodents. Rats were fed either a chow or high-fat/high-sucrose (HFHSu) diet (60% lipid-rich diet plus 35% sucrose drinking water) over 14 weeks. Neural interfaces were bilaterally implanted in the CSNs and attached to an external pulse generator. The rats were then randomised to KHFAC or sham modulation groups. KHFAC modulation variables were defined acutely by respiratory and cardiac responses to hypoxia (10% O 2  + 90% N 2 ). Insulin sensitivity was evaluated periodically through an ITT and glucose tolerance by an OGTT. KHFAC modulation of the CSN, applied over 9 weeks, restored insulin sensitivity (constant of the insulin tolerance test [K ITT ] HFHSu sham, 2.56 ± 0.41% glucose/min; K ITT HFHSu KHFAC, 5.01 ± 0.52% glucose/min) and glucose tolerance (AUC HFHSu sham, 1278 ± 20.36 mmol/l × min; AUC HFHSu KHFAC, 1054.15 ± 62.64 mmol/l × min) in rat models of type 2 diabetes. Upon cessation of KHFAC, insulin resistance and glucose intolerance returned to normal values within 5 weeks. KHFAC modulation of the CSN improves metabolic control in rat models of type 2 diabetes. These positive outcomes have significant translational potential as a novel therapeutic modality for the purpose of treating metabolic

Spanish Nuclear Safety Council strategy in nuclear communication

International Nuclear Information System (INIS)

Perez, Angeles; Perez Baez, Antonio

2002-01-01

The Spanish regulator agency has functions in communication established by the legislation. One of the duties settled by the Law 15/1980 creating the CSN was to: 'inform the public on matters of its competence'. On the other hand, an European Directive 89/618/EURATOM requires to the duty to inform the population about the measures in emergency situations. The Spanish regulator has a double roll: - to tell everybody what it does, its activities; - to teach people how to behave in a radiological emergency. In order to get the goals, our strategy firstly has determined public interests and split the population/audience into target groups, secondly we have designed the suitable programs and the activities according to them and finally we check the results. To perform this strategy we develop these work areas: 1. Relations with the media in which the information is provided by CSN initiatives through press releases, press conferences, specific information sessions, distribution of publications and participation of journalists in emergency simulation drills. When the information responses to demands, we telephone attention to requests for information and interviews with the press, radio and television. 2. Public information interactive centre, available since April 1997, with priority given in design to school visits in which we inform on the radiation nature, uses and risks, how a nuclear power plant works, the radwaste manage, the CSN's functions, etc. 3. Issuing of publications not only technical as the Annual report to Parliament or the Quarterly journal but informative, all are free of charge. 4. Internet information-nation service where we inform on operational state of Spanish installations. radiological values of the environment, last press releases, the research and development projects, last publications, and breaking news. As the conclusion we have to say that most than the 60 percent of Spaniards know what is the CSN and what are the benefits of the radiation

Novel Cyclosilazane-Type Silicon Precursor and Two-Step Plasma for Plasma-Enhanced Atomic Layer Deposition of Silicon Nitride.

Science.gov (United States)

Park, Jae-Min; Jang, Se Jin; Lee, Sang-Ick; Lee, Won-Jun

2018-03-14

We designed cyclosilazane-type silicon precursors and proposed a three-step plasma-enhanced atomic layer deposition (PEALD) process to prepare silicon nitride films with high quality and excellent step coverage. The cyclosilazane-type precursor, 1,3-di-isopropylamino-2,4-dimethylcyclosilazane (CSN-2), has a closed ring structure for good thermal stability and high reactivity. CSN-2 showed thermal stability up to 450 °C and a sufficient vapor pressure of 4 Torr at 60 °C. The energy for the chemisorption of CSN-2 on the undercoordinated silicon nitride surface as calculated by density functional theory method was -7.38 eV. The PEALD process window was between 200 and 500 °C, with a growth rate of 0.43 Å/cycle. The best film quality was obtained at 500 °C, with hydrogen impurity of ∼7 atom %, oxygen impurity less than 2 atom %, low wet etching rate, and excellent step coverage of ∼95%. At 300 °C and lower temperatures, the wet etching rate was high especially at the lower sidewall of the trench pattern. We introduced the three-step PEALD process to improve the film quality and the step coverage on the lower sidewall. The sequence of the three-step PEALD process consists of the CSN-2 feeding step, the NH 3 /N 2 plasma step, and the N 2 plasma step. The H radicals in NH 3 /N 2 plasma efficiently remove the ligands from the precursor, and the N 2 plasma after the NH 3 plasma removes the surface hydrogen atoms to activate the adsorption of the precursor. The films deposited at 300 °C using the novel precursor and the three-step PEALD process showed a significantly improved step coverage of ∼95% and an excellent wet etching resistance at the lower sidewall, which is only twice as high as that of the blanket film prepared by low-pressure chemical vapor deposition.

Purines and Carotid Body: New Roles in Pathological Conditions

Directory of Open Access Journals (Sweden)

Silvia V. Conde

2017-12-01

Full Text Available It is known that adenosine and adenosine-5′-triphosphate (ATP are excitatory mediators involved in carotid body (CB hypoxic signaling. The CBs are peripheral chemoreceptors classically defined by O2, CO2, and pH sensors. When hypoxia activates the CB, it induces the release of neurotransmitters from chemoreceptor cells leading to an increase in the action potentials frequency at the carotid sinus nerve (CSN. This increase in the firing frequency of the CSN is integrated in the brainstem to induce cardiorespiratory compensatory responses. In the last decade several pathologies, as, hypertension, diabetes, obstructive sleep apnea and heart failure have been associated with CB overactivation. In the first section of the present manuscript we review in a concise manner fundamental aspects of purine metabolism. The second section is devoted to the role of purines on the hypoxic response of the CB, providing the state-of-the art for the presence of adenosine and ATP receptors in the CB; for the role of purines at presynaptic level in CB chemoreceptor cells, as well as, its metabolism and regulation; at postsynaptic level in the CSN activity; and on the ventilatory responses to hypoxia. Recently, we have showed that adenosine is involved in CB hypersensitization during chronic intermittent hypoxia (CIH, which mimics obstructive sleep apnea, since caffeine, a non-selective adenosine receptor antagonist that inhibits A2A and A2B adenosine receptors, decreased CSN chemosensory activity in animals subjected to CIH. Apart from this involvement of adenosine in CB sensitization in sleep apnea, it was recently found that P2X3 ATP receptor in the CB contributes to increased chemoreflex hypersensitivity and hypertension in spontaneously hypertension rats. Therefore the last section of this manuscript is devoted to review the recent findings on the role of purines in CB-mediated pathologies as hypertension, diabetes and sleep apnea emphasizing the potential

Rapid characterization of seismic sources in Chile: Contribution of the GNSS component

Science.gov (United States)

Barrientos, S. E.; Riquelme, S.; Baez, J. C., Sr.

2017-12-01

The recently created National Seismological Center (CSN) of the University of Chile was tasked to upgrade the countrýs seismic network in 2013. The upgrade included new 65 collocated accelerometer and broadband instruments together with 130 GNSS devices designed to transmit their data in real time. Forty units of the GNSS devices include the RTX option, a real time 1-Hz positioning capability at 4-cm error level. The observation system is complemented with 297 additional stand-alone strong motion instruments mainly located in basins for seismic engineering purposes. Broadband data can be accessed in real time from IRIS Data Management Service under networks C and C1. Strong motion event data can be retrieved through the CSN database (evtdb.csn.uchile.cl). A server is being established to handle GNSS data requests through an NTRIP Caster. Completion of the connectivity of the GNSS remote units to the main acquisition servers is expected to take place within several months. In addition to the 40 units providing real time positioning through the RTX option, Precise Point Positioning (PPP) algorithms are being tested on the CSN main servers to enable real time estimates every second for all GNSS remote devices. Because of the high earthquake productivity rate in Chile, the RTX system capabilities have been positively tested in two cases already, demonstrating their excellent performance: i) the main aftershock (M7.6) of the April 1, 2014, northern Chile event and ii) the April 24, 2017, (M6.9) event in central Chile. The former produced coastal horizontal static displacements of the order of 30 cm while the latter of the order of 5 cm. In addition to rapid earthquake characterization through static deformation, W-phase displacement waveform inversions are included in the fast analysis providing excellent results. These new applications and methodologies have profoundly impacted the rapid evaluation of the tsunamigenic potential of large earthquakes in the near field.

Instrukce k citování literatury dostupné v prostředí WWW na vysokých školách v ČR. Analýza a hodnocení na základě standardu ČSN ISO 690 a ČSN ISO 690-2

OpenAIRE

Kubálková, Petra

2006-01-01

Bakalárská práce se zameruje na popis a utrídení textu instrukcí k citování literatury lokalizovaných na WWW serverech vysokých škol v CR. V úvodní cásti práce jsou strucne popsány pojmy informacní etika a citacní etika a vysvetlen vztah bibliografických citací k Autorskému zákonu Ceské republiky. Zvláštní pozornost je venována platným normám pro bibliografické citování (CSN ISO 690 a CSN ISO 690-2), které jsou podrobne analyzovány v druhé kapitole. Tretí kapitola nabízí rozbor reprezentantu ...

Regulatory challenges in the management of aging of structural materials in nuclear power plants; Retos reguladores en la gestion del envejecimiento de los materiales estructurales de centrales nucleares

Energy Technology Data Exchange (ETDEWEB)

Castelo, C.; Mendoza, C.; Mas, E.; Conde, J. M.

2013-07-01

The article discusses two major pathways by which a regulatory body, and in particular the CSN, may participate in the acquisition of the necessary knowledge on mechanisms of aging of nuclear structural materials: to participate in forums to share operational experience and R and R project, both nationally and internationally. It notes the importance of this participation to carry out its regulatory function based on the knowledge acquired and the unique challenge of transferring that knowledge to rules and guidelines for their application. The article discusses various R and D projects in which the CSN participates directly. It calls for the presence of regulatory bodies in R and D project funded by the EU and the transfer of the results of such projects to codes, standards or guidelines for feasible implementation. (Author)

[Breast hematoma and cytosteatonecrosis. Apropos of 55 cases].

Science.gov (United States)

Gollentz, B; Ballarini, P; Rossier, S; Chagué, D

1990-01-01

The authors report a retrospective study of 55 cases, 34 hematomas and 21 cytosteatonecrosis (CSN) of the breast, during 15 years. The mammary hematoma can appear with an encapsuled or diffused form, or in 40% of cases without radiographic model. The diagnosis of CSN, is easy, such as ringed, macrocalcified, or oil cystic, but when it is the case of solid cicatriciel mass, it is difficult to distinguish it from mammary carcinoma, in approximatively half of the cases. The etiopathogenic discussion, display, traumatic features, ischemic cellular disease, such as mammary infarct, inflammatory lesions, duct ectasia, anticoagulant drugs, needle aspiration... Even though nodular lesion may be a carcinoma, a very suggestive lesion with spicules and skin retraction may be benign. The follow up, or histological examination by biopsie or surgery, is always essential.

Regulatory challenges in the management of aging of structural materials in nuclear power plants

International Nuclear Information System (INIS)

Castelo, C.; Mendoza, C.; Mas, E.; Conde, J. M.

2013-01-01

The article discusses two major pathways by which a regulatory body, and in particular the CSN, may participate in the acquisition of the necessary knowledge on mechanisms of aging of nuclear structural materials: to participate in forums to share operational experience and R and R project, both nationally and internationally. It notes the importance of this participation to carry out its regulatory function based on the knowledge acquired and the unique challenge of transferring that knowledge to rules and guidelines for their application. The article discusses various R and D projects in which the CSN participates directly. It calls for the presence of regulatory bodies in R and D project funded by the EU and the transfer of the results of such projects to codes, standards or guidelines for feasible implementation. (Author)

The environmental radiation monitoring system in Spain El sistema de vigilancia radiológica ambiental en España

Directory of Open Access Journals (Sweden)

Carmen Rey del Castillo

2010-12-01

Full Text Available The system of environmental radiation monitoring established in Spain is composed of several networks with different objectives, a monitoring network in the vicinity of the facilities and several national networks financed and managed by public agencies. The operators of the facilities are responsible for the conduct of its Environmental Radiological Surveillance Program as directed by the CSN. Moreover, the Directorate General of Civil Defense and Emergencies has a Radioactivity Warning Network (RAR consisting of over 900 automatic stations measuring dose rate distributed nationwide. The Environmental Radioactivity Monitoring Network (Revira, managed by the CSN, is a nationwide network, consists of a Network of Sampling Stations (REM and a Network of Automatic Stations for continuous monitoring (REA. The autonomous communities of Valencia, Catalonia, Extremadura and the Basque Country have their own automated networks similar to that of the CSN. Revira provides information on the radioactivity in the air, soil, water (drinking, inland and sea and of food. The sampling and analysis programs are tailored to radiological recommendations laid down in the European Union Commission. The REM has the collaboration of laboratories in universities and the Centre for Energy, Environmental and Technological Research (CIEMAT for execution. The monitoring of inland and coastal waters is undertaken by the Centre for Studies and Experimentation of Public Works, Ministry of Public Works (CEDEX.El sistema de vigilancia radiológica del medio ambiente establecido en España está constituido por varias redes con diferentes objetivos: una red de vigilancia en el entorno de las instalaciones y varias redes de ámbito nacional financiadas y gestionadas por organismos públicos. Los titulares de las instalaciones son los responsables de la realización de sus programas de vigilancia radiológica ambiental siguiendo las directrices del Consejo de Seguridad Nuclear

Evaluación de la exactitud posicional vertical de una nube de puntos topográficos Lidar usando topografía convencional como referencia

Directory of Open Access Journals (Sweden)

Wilver Enrique Salinas Castillo

2013-11-01

Full Text Available La exactitud vertical de datos lidar es normalmente establecida por proveedores comerciales en un EMC máximo de 0.150 m. Sin embargo, los resultados de evaluaciones de exactitud en las que se han utilizado datos de campo por lo menos tres veces más exactos que los datos lidar, sugieren que dicha exactitud se observa solo cuando la densidad de los datos lidar es mayor a un punto sobre el terreno por metro cuadrado. Desafortunadamente, el número de estos estudios es limitado y se requiere de la elaboración de otras evaluaciones que confirmen dicha hipótesis. En este estudio se evaluó la exactitud vertical de una nube de puntos topográficos lidar de una densidad de 1.02 puntos sobre el terreno por metro cuadrado, usando como referencia datos recolectados en campo mediante una estación total. Los resultados coinciden con aquéllos de estudios previos, por lo que se sugiere establecer la EPV de la nube de puntos topográficos lidar en 0.200 m para terreno mixto y de cambios constantes y en 0.150 m para terreno con cambios topográficos gentiles. Sin embargo, la EPV no refleja la magnitud del 95% de los errores bajo la presencia de errores sistemáticos, por lo cual es necesario incluir el percentil 95 de los errores en la documentación de datos lidar

Radiological evaluation of an industrial complex of phosphate fertilizer production in response to the current regulations on health protection against ionizing radiation; Evaluacion radiologica de un complejo industrial de produccion de fertilizantes fosfatado al actual reglamento sobre proteccion sanitaria contra radiaciones ionizantes

Energy Technology Data Exchange (ETDEWEB)

Mosqueda Pena, F.; Bolivar Raya, J. P.

2011-07-01

We performed a comprehensive study of the radioactive and radiological follow NORM industrial complex, in addition to that regulation, the Criteria for radiological protection against exposure to natural radiation issued by the Nuclear Safety Council (CSN).

International Conference on Promotion of the Global Application of Decommissioning and Environmental Restoration Programmes; Conferencia Internacional sobre el Fomento de la Aplicacion global de Programas de Clausura y Restauracion Medioambiental

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-08-01

The Conference on Promotion of the Global Application of Decommissioning and Environmental Restoration Programmes, organised by the International Atomic Energy Agency (IAEA) with CSN participation, was held in Madrid between May 23rd and 27th. (Author)

Formalization of common power and efficiency definitions for energy-converting intracellular biochemical processes

Energy Technology Data Exchange (ETDEWEB)

Santillan, M.; Angulo-Brown, F.; Chavoya-Aceves, O. [Instituto Politecnico Nacional, Mexico, D. F. (Mexico)

2001-04-01

The definitions of power and efficiency for energy-converting intracellular biochemical processes, introduced by Caplan and Essig are studied. These definitions are recovered in the present work with the formalism of De Groot and Mazure for First-Order Irreversible Thermodynamics, rather than the formalism of Prigogine, as done by Caplan and Essig. The approach here employed permits to keep track of all the assumptions in a more clear manner, and to get rid of a very strong restriction in the approach of Caplan and Essig which assumes that the chemical potentials are homogeneous inside the cell. [Spanish] Se estudian las definiciones de potencia y eficiencia para procesos bioquimicos intracelulares convertidores de energia, introducidas por Caplan y Essig. En el presente trabajo, dichas definiciones se recuperan usando el formalismo de De Groot y Mazur para la termodinamica irreversible de primer orden, en vez del formalismo de Prigogine, empleado por Caplan y Essig. El punto de vista empleado en el presente manuscrito permite seguir las suposiciones hechas de una manera mas clara, ademas de que hace innecesaria una suposicion bastante fuerte usada por Caplan y Essig, la cual da por hecho que los potenciales quimicos son homogeneos en el interior de la celula.

Optimization of Saanen sperm genes amplification: evaluation of standardized protocols in genetically uncharacterized rural goats reared under a subtropical environment.

Science.gov (United States)

Barbour, Elie K; Saade, Maya F; Sleiman, Fawwak T; Hamadeh, Shady K; Mouneimne, Youssef; Kassaifi, Zeina; Kayali, Ghazi; Harakeh, Steve; Jaber, Lina S; Shaib, Houssam A

2012-10-01

The purpose of this research is to optimize quantitatively the amplification of specific sperm genes in reference genomically characterized Saanen goat and to evaluate the standardized protocols applicability on sperms of uncharacterized genome of rural goats reared under subtropical environment for inclusion in future selection programs. The optimization of the protocols in Saanen sperms included three production genes (growth hormone (GH) exons 2, 3, and 4, αS1-casein (CSN1S1), and α-lactalbumin) and two health genes (MHC class II DRB and prion (PrP)). The optimization was based on varying the primers concentrations and the inclusion of a PCR cosolvent (Triton X). The impact of the studied variables on statistically significant increase in the yield of amplicons was noticed in four out of five (80%) optimized protocols, namely in those related to GH, CSN1S1, α-lactalbumin, and PrP genes (P 0.05). The applicability of the optimized protocols of Saanen sperm genes on amplification of uncharacterized rural goat sperms revealed a 100% success in tested individuals for amplification of GH, CSN1S1, α-lactalbumin, and MHC class II DRB genes and a 75% success for the PrP gene. The significant success in applicability of the Saanen quantitatively optimized protocols to other uncharacterized genome of rural goats allows for their inclusion in future selection, targeting the sustainability of this farming system in a subtropical environment and the improvement of the farmers livelihood.

Gclust Server: 36149 [Gclust Server

Lifescience Database Archive (English)

Full Text Available 36149 Bsu_BSU26890=csn Cluster Sequences - 277 chitosanase 3 1.00e-25 0.0 0.0 0.0 0...nces Link to related sequences - Sequence length 277 Representative annotation chitosanase Number of Sequenc

Solución de redes de flujo para gases usando el modelo de balance de nodos y el método de linealización de ecuaciones

Directory of Open Access Journals (Sweden)

Paulo César Narváez

1999-09-01

Full Text Available El dimensionamiento de redes de distribución de gases es un problema complejo, tanto por la diversidad de los fenómenos que se presentan, como por la variación de las propiedades de los fluidos, en especial, la densidad por efecto de los cambios en la presión a lo largo de la red. Este trabajo presenta un modelo para su simulación a partir de la deducción de la ecuación general de flujo en estado estable e isotérmico, su inclusión en el modelo de balance de nodos y la solución de este por el método de linealización de ecuaciones. Adicionalmente, se hace un resumen de las ecuaciones empíricas más usadas para el cálculo de la caída de presión para gases fluyendo en tuberías y un ejemplo que ilustra la aplicación del modelo y el método desarrollado.

Ceratectomia lamelar anterior profunda usando a técnica "big-bubble" em pacientes com ceratocone

Directory of Open Access Journals (Sweden)

Sandro Antonini Coscarelli

2012-02-01

Full Text Available OBJETIVOS: Avaliar através de um estudo retrospectivo pacientes com ceratocone, a partir do 12º mês após a ceratectomia lamelar anterior profunda usando a técnica "big-bubble". MÉTODOS: Estudo retrospectivo de consecutivos 79 olhos de 71 pacientes com ceratocone moderado a grave, com baixa acuidade visual após as correções ópticas e intolerantes à adaptação de lente de contato. Todos os transplantes foram realizados pelo mesmo experiente cirurgião, no período de janeiro de 2007 a fevereiro de 2009, utilizando a técnica de ceratectomia lamelar anterior profunda pelo "big-bubble". Os dados analisados foram sexo, idade, paquimetria corneana, densidade endotelial, astigmatismo dinâmico e melhor acuidade visual corrigida (BCVA após a ceratectomia. RESULTADOS: A idade média verificada foi de 30,4 (± 10,2 anos, com 39 (54,9% do sexo feminino e 32 (45,1% do masculino. A paquimetria ultrassônica média foi de 518,6 (± 29,5 μm. Setenta e dois (91,1% dos transplantes realizados obtiveram acuidade visual dinâmica corrigida melhor ou igual a 20/50. A média do astigmatismo dinâmico foi de - 3,5 (± 1,5 dioptrias cilíndricas. A média da densidade endotelial encontrada conforme a faixa etária teve a distribuição com os pacientes de 11 a 20 anos com 3.053 (± 532 cél/mm²; 21 a 30 anos com 2.674 (± 725 cél/mm²; 31 a 40 anos com 2.737 (± 575 cél/mm²; 41 a 50 anos com 2.585 (± 476 cél/mm² e 51 a 60 anos com 2.398 (± 667 cél/mm². Microperfuração no per-operatório teve uma incidência de 8,8%. CONCLUSÃO: A ceratectomia lamelar anterior profunda pela técnica "big-bubble" é um valioso tratamento para pacientes com ceratocone, alcançando uma melhor acuidade visual corrigida final semelhante ao transplante penetrante. A contagem média de células endoteliais apresenta-se dentro da normalidade para a faixa etária após o procedimento. Não foram encontradas córneas rejeitadas ou com edema após a retirada de todos os

Desenvolvimento de software e hardware para irrigação de precisão usando pivô central Development of software and hardware for precision irrigation using the center pivot

Directory of Open Access Journals (Sweden)

Tadeu M. de Queiroz

2008-03-01

Full Text Available O presente trabalho teve por objetivo desenvolver softwares e hardwares para aplicação ao monitoramento e controle automático para a irrigação de precisão usando sistemas do tipo pivô central. O trabalho foi desenvolvido no Departamento de Engenharia Rural - LER, da Escola Superior de Agricultura "Luiz de Queiroz" - ESALQ, da Universidade de São Paulo - USP, em Piracicaba - SP. Foram utilizados componentes eletrônicos discretos, circuitos integrados diversos, módulos de radiofreqüência, microcontroladores da família Basic Step e um microcomputador. Foram utilizadas as linguagens Delphi e TBasic. O hardware é constituído de dois circuitos eletrônicos, sendo um deles para "interface" com o computador e o outro para monitoramento e transmissão da leitura de tensiômetros para o computador via radiofreqüência. Foram feitas avaliações do alcance e da eficiência na transmissão de dados dos módulos de radiofreqüência e do desempenho do software e do hardware. Os resultados mostraram que tanto os circuitos quanto os aplicativos desenvolvidos apresentaram funcionamento satisfatório. Os testes de comunicação dos rádios indicaram que esses possuem alcance máximo de 50 m. Concluiu-se que o sistema desenvolvido tem grande potencial para utilização em sistemas de irrigação de precisão usando pivô central, bastando para isso que o alcance dos rádios seja aumentado.The objective of this work was to develop softwares and hardwares applied to the management and automatic control for precision irrigation using center pivot systems. They were developed in the Rural Engineering Department - LER, at the "Luiz de Queiroz" College of Agriculture - ESALQ, of São Paulo University - USP, in Piracicaba, SP-Brazil. It was used discrete electronic components, several integrated circuits, radio frequency modules, microcontrollers from the Basic Step family and a microcomputer. The computer software was developed in Delphi language, and

Seismic Tomography of the Near Solar Surface L. Gizon1, Τ. L ...

Indian Academy of Sciences (India)

tribpo

Local helioseismology diagnostics open the prospect of mapping the three dimen ... 1998 December 6 in the MDI high resolution field of view (Scherrer et al. 1995) ... CSN and CIO, which depend on correlation time τ and distance from x. They.

Aerotaxis in Desulfovibrio

DEFF Research Database (Denmark)

Wieland, Andrea Karin Eschemann; Kühl, Michael; Cypionka, H.

1999-01-01

Aerotaxis of two sulphate-reducing bacteria, the freshwater strain Desulfovibrio desulfuricans CSN (DSM 9104) and the marine strain Desulfovibrio oxyclinae N13 (DSM 11498), was studied using capillary microslides, microscopy and oxygen microsensors. The bacteria formed ring-shaped bands in oxygen...

Status of the Review of Electric Items in Spain Related to the Post-Fukushima Stress Test Programme

International Nuclear Information System (INIS)

Martinez Moreno, Manuel R.; Perez Rodriguez, Alfonso

2015-01-01

Spain Authorities has established a comprehensive compilation of the actions currently related to the post-Fukushima program. It has been initiated both at national and international level and it is developed in an Action Plan. This Plan is aligned to the 6 topics identified in the August 2012 CNS-EOM report, and organized in four parts. One of these parts is related to the loss of electrical power and with a clear objective in implemented new features on increase robustness. This program has been reinforced and the task of Electric Issues has been incremented as a consequence of this Plan. The normal tasks of the Electric Systems and I and C Branch will be presented with the Fukushima related issues as well. The Consejo de Seguridad Nuclear -CSN-(Nuclear Safety Council) maintains a permanent program of control and surveillance of nuclear safety issues in Spanish Nuclear Power Plants. The Electric Systems and I and C Branch of the CSN have different tasks related Electric Issues: - Inspection, control and evaluation of different topics in normal and accidents operation. - Surveillance Testing Inspections. - Design Modifications Inspections and evaluation. - Reactive inspections - Other activities: Participation in Escered project (a before Fukushima Accident) with an objective of analyzed exterior grid stability and check that electric faults in the NPPs vicinity did not cause the simultaneous loss of the offsite supplies fault effects with interaction in inner related systems. Other task related with the management of aging and long-term operation. Now, as a consequence, it has been incremented its task with some new Fukushima related topics: - Analysis of beyond accident related with U.S. SBO Rule (Reg. Guide 1.155) is a part of the design bases for the Spanish plants designed by Westinghouse/ General Electric; switchyard/grid events and extreme weather events are considered, with 10 minutes to connect an alternate source (if provided; if not, use of d

ESTUDO DOS COMPRIMENTOS DE LIGAÇÃO DA FORMA CETÔNICA DA CURCUMINA NO VÁCUO USANDO DINÂMICA MOLECULAR DE CAR-PARRINELLO

Directory of Open Access Journals (Sweden)

Eduardo MartinsToledo

2015-03-01

Full Text Available A curcumina é um pigmento amarelo-laranja extraído do rizoma da planta Curcuma longa L. Tem-se destacado por apresentar um amplo potencial terapêutico, com atividade antibacteriana, anti-inflamatória, antioxidante, pró-apoptótica, quimiopreventiva, anticarcinogênica entre outras. Apesar das diversas propriedades biológicas identificadas, existem poucos estudos teóricos sobre este candidato a fármaco. Nesse sentido, o presente trabalho objetivou-se no estudo dos comprimentos de ligação da forma cetônica da curcumina no vácuo, utilizando o método de Dinâmica Molecular de Car-Parrinello. Para os cálculos, a molécula foi disposta em uma caixa cúbica, com dimensões de 23 Å. O funcional de energia de troca e correlação foi modelado usando o funcional do gradiente corrigido PBE. Os elétrons do núcleo foram tratados com pseudopotenciais ultrasolf de Vanderbilt, e os de valência foram representados pelo conjunto de funções de base em ondas planas, truncadas em energia cinética de corte de 20 Ry. As simulações de DMCP foram realizadas a 300 K, com um passo de integração de 6,0 a.t.u. e massa fictícia de 500 a.u. Os resultados mostram uma boa concordância com as propriedades estruturais da forma cetônica da curcumina determinadas por outros métodos teóricos. Este estudo contribui para a compreensão inicial das propriedades estruturais da forma cetônica da curcumina.

Valoración de la formación recibida usando un perfil de referencia basado en competencias profesionales Valuation the formation using a profile of reference based on professional competences

Directory of Open Access Journals (Sweden)

Mónica Maldonado Rojas

2007-12-01

Full Text Available Introducción: La formación profesional está hoy en día promoviendo la implementación de opciones educativas basadas en modelos por competencias. El presente trabajo tuvo como propósito establecer un perfil de referencia basado en competencias profesionales para la carrera de Tecnología Médica de la Universidad de Talca y usando éstas como indicadores, conocer la auto percepción que tienen los egresados respecto del grado en que fueron adquiridas durante su formación. Material y métodos: Se realizó una investigación de tipo exploratoria, mediante una encuesta autoaplicada que contenía un conjunto de indicadores que correspondían a competencias establecidas previamente en un perfil de referencia, cuya estructura considera diferentes áreas de desempeño. El perfil fue validado por juicio de expertos, determinando el grado de congruencia a través del coeficiente de Serafine. La construcción de la información se realizó a partir de las repuestas, las que fueron codificadas y representadas en porcentajes y posteriormente analizadas bajo categorías interpretativas. Resultados: La evaluación que se hace considera el porcentaje de egresados que valoró el logro de las competencias por área de desempeño en los niveles más altos. Los resultados obtenidos fueron: Para el área asistencial el 72,9 %, para el área investigación un 59 %, para el área de docencia un 44%, para el área administrativa un 27,1% y para el área personal-social un 91,3 %. Conclusiones: Siguiendo el criterio de categorías interpretativas, el área personal social indica una gran fortaleza de la formación, el área asistencial y el área investigación se encuentran en un nivel satisfactorio y las áreas docencia y administración en niveles medianamente satisfactorio, siendo esta última la gran falencia de la formación. El currículo vigente es adecuado para asegurar el logro de gran número de competencias, pero se debe revisar con el objetivo de

On the impact of pacific ocean free tropospheric background aerosols at the surface of the earth-atmosphere system

Energy Technology Data Exchange (ETDEWEB)

DeFelice, T. P. [Dept. Geosciences, A.S.G., University of Wisconsin-Milwaukee (United States)

1997-10-01

Individual tropospheric particles (0.03 to several {mu}m in diameter) were sampled using wire impactors on a DC-864 aircraft along and within Pacific Rim, from 125 degrees E to 120 degrees W and 70 degrees S to 70 degrees N, during the November 1989 and May 1990 Global Backscattering Experiment (GLOBE) deployments of NASA. A simple radiative balance model was used to determine the first order radiative effect of this aerosol layer at the surface. The results indicate that: (i) The background (optical thickness of {approx_equal}0.005) tropospheric aerosols between 2.4 - 12.2 km exert a warming tendency on surfaces with albedos {>=}0.02 in both the visible and infrared. (ii) There is an apparent increase in the coarse mode sulfur containing aerosol abundance compared to {approx_equal} 15 years ago, suggesting that the background aerosol layer exerted a stronger tendency of planetary warming {approx_equal} 15 years ago. [Spanish] Se muestrearon particulas troposfericas individuales (0.03 a varias {mu}m de diametro) usando impactadores de alambre en un avion DC-864 a lo largo y dentro de la region del Pacifico de 125 grados E a 120 grados W y 70 grados S a 70 grados N, durante los desplegamientos de NASA del Experimento Global de Retrospeccion (GLOBE) en noviembre de 1989 y mayo de 1990. Fue usado un modelo de balance simple de radiacion para determinar el efecto radiativo de primer orden de esta capa de aerosoles en la superficie. Los resultados indican que: (i) los aerosoles troposfericos de fondo (espesor optico de {approx_equal} 0.05) entre 2.4 - 12.2 km ejercen una tendencia al calentamiento sobre superficies con albedo {>=} 0.02, tanto en el visible como en el infrarrojo. (ii) hay un aparente aumento en el modo tosco del sulfuro conteniendo abundancia de aerosoles comparado con {approx_equal} hace 15 anos, sugiriendo que la capa de trasfondo de aerosoles ejercio una tendencia mas fuerte de calentamiento planetario {approx_equal} hace 15 anos.

A regulator's perspective on the use of analogues for regulatory confidence

International Nuclear Information System (INIS)

Ruiz, Carmen

2008-01-01

The NAA Study, promoted and coordinated by the CSN, was carried out in collaboration with ENRESA by CIEMAT and three Spanish Universities UZ, UDC and UCM. The 3 year Study, included in the CSN's R and D Programme, started in 1999, is focussed on Deep Geological disposal (DGD). CSN motivation for NA Analogues arose in 1997 as result of the emerging approaches to increase the confidence in the Safety Assessment (SA) considering multiple lines of reasoning show in: some international documents and some national regulation. After a first preliminary (1997-1998) study, the CSN noticed the large amount and dispersion of the information about NNA, and decided to launch a deeper Study with the aims of: Collecting and reviewing the results of all the relevant studies on analogues developed in the last decades in systematic way; Reaching a better understanding of their potential and real application to the SA and for communication purposes. The results of the Analogue Study has been structured in several documents with different levels of detail and technical content addressed to different audiences. Analogue studies are a source of knowledge for the understanding of the long-term behavior of DGD systems. They represent a complementary method to increase Confidence Building within PA. In the majority of the cases, analogues have been used to transmit information on generic aspects of the geological concept an easily understood message. The need to simplify the content to facilitate their understanding may imply different information to different audiences. Analogue studies are: Considered within the multiple lines of reasoning to increase the confidence in the SA; A source of knowledge for the understanding of the long-term behavior of DGD systems. They represent a complementary method to increase Confidence Building within SA. There are few examples of the direct use of data from natural analogue projects in the consulted SA. They are promoted by International organisations

75 FR 65383 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Telemanagement Forum

Science.gov (United States)

2010-10-22

... Telecoms Business Unit, Copenhagen, DENMARK; Eastek Pty Ltd, Melbourne, Victoria, AUSTRALIA; EMBRATEL, Rio de Janeiro, BRAZIL; Engineering IT, Pont St. Martin (AO), ITALY; Eutelsat S.A., Paris, FRANCE; EWE... de Cantv, Edificio Cortijos 1, VENEZUELA; Column Technologies, Downers Grove, IL; CSN Technology Pty...

Radiological investigation of drinking water

International Nuclear Information System (INIS)

Kunz, E.

1981-01-01

An analysis is made of the report ''Radiological investigation of drinking water'' submitted by a working group of WHO to the Brussels meeting held between Nov 7 and 10, 1978. Annex II is emphasized of the WHO publication bearing the title ''The revision of WHO standards for drinking water''. It is shown that the draft of the revision does not basically differ from the revision introduced in Czechoslovakia and published in a revised standard CSN 83 0611 Drinking Water from 1978, including its harmonization with the Decree 59/72 Collect. of Laws on the protection of health from ionizing radiation, and from the standard CSN 83 0523 Radiometric analysis of drinking water. It is also shown that the text of the working group report contains some incorrect or unclear statements and views, which is explained by the misunderstanding of some ICRP recommendations. (H.S.)

Evaluation of the Water Requirements for a Greenhouse Tomato Crop using the Priestley-Taylor Method Evaluación del Consumo de Agua de un Cultivo de Tomate en Invernadero Usando el Método de Priestley-Taylor

Directory of Open Access Journals (Sweden)

Héctor Valdés-Gómez

2009-03-01

Full Text Available The Priestley-Taylor (PT model was evaluated for estimating the real evapotranspiration (ETreal of a drip-irrigated greenhouse tomato (Lycopersicon esculentum Mill. crop. The net radiation incorporated in the PT model was estimated using meteorological variables. For this experiment, an automatic weather station (AWS was installed inside the greenhouse to measure solar radiation (Rgi, net radiation (Rn, air temperature (Ta and relative humidity (RH. Another AWS was installed over a grass cover to measure atmospheric conditions outside the greenhouse. The experiment was carried out at the Panguilemo experimental station (35°23' S, 71°40' W, 110 m.a.s.l. from August to December 2000. The PT model was evaluated using the ETreal obtained from the water balance (WB method. In this case, values of ETreal by PT model were calculated using: a Rgi and soil heat flux (G = 0; b Rgi and G ≠ 0; c solar radiation measured outside the greenhouse (Rge and G = 0; and d Rge and G ≠ 0. For these cases, results indicated that PT model was able to compute ETreal with errors less than 5%. Also, Rn was calculated with a relative absolute error and a mean deviation lower than 6% and 0.07 mm d-1, respectively, using Rgi or Rge. Daily soil heat flux values equal to zero did not affect the calculation of ETreal values. Thus, the PT model evaluated in this study could be used for scheduling irrigation for a greenhouse tomato crop, using internal measurements of air temperature and relative humidity, and external measurements of solar radiation. In this case, PT model predicted the ETreal with an error of 6.1%.Se evaluó el comportamiento del modelo de Priestley-Taylor (PT para la estimación de la evapotranspiración real (ETreal de un cultivo de tomates (Lycopersicon esculentum Mill. en condiciones de invernadero. La radiación neta incorporada en el modelo de PT fue calculada usando variables meteorológicas clásicas. Para este experimento, una estación meteorol

QTL list: Swf-2 [PGDBj Registered plant list, Marker list, QTL list, Plant DB link and Genome analysis methods[Archive

Lifescience Database Archive (English)

Full Text Available QT98651 Cucumis sativus Cucurbitaceae Swf-2 resistance to Melon yellow spot virus ...resistance to Melon yellow spot virus MYSV-FuCu05P 3 CSN251 Chr03 ... 34.0-56.0 11 ... 10.1007/s10681-015-1444-x ...

Case report

African Journals Online (AJOL)

abp

13 août 2015 ... This is an Open Access article distributed under the terms of the Creative ... Published in partnership with the African Field Epidemiology Network (AFENET). ... cas associé à une cytostéatonécrose néonatale (CSN), traité par.

Process control of Low and Intermediate-level radioactive wastes solidification

International Nuclear Information System (INIS)

1993-01-01

Safety guidelines issued by the Spanish Council of Nuclear Safety (CSN) with basic criteria which must be adopted for the control of the Process for wastes solidification, establishing, in addition, a series of protocols and basic contents to assist the elaboration of Process Control Programs

Selection for genetic markers in beef cattle reveals complex associations of thyroglobulin and casein1-S1 with carcass and meat traits

Science.gov (United States)

Genetic markers in casein (CSN1S1) and thyroglobulin (TG) genes have previously been associated with fat distribution in cattle. Determining the nature of these genetic associations (additive, recessive, or dominant) has been difficult because both markers have small minor allele frequencies in mos...

76 FR 77107 - Airworthiness Directives; Pratt & Whitney Corp. (PW) JT9D-7R4H1 Turbofan Engines

Science.gov (United States)

2011-12-12

.... FOR FURTHER INFORMATION CONTACT: Stephen K. Sheely, Aerospace Engineer, Engine Certification Office...; email: stephen[email protected] . SUPPLEMENTARY INFORMATION: Discussion We issued a notice of proposed... AD, remove the HPC shaft from service before exceeding 5,000 CSN. (h) Engines With an HPC Shaft, P/N...

Effect of liquid sodium on long-term properties of austenitic steels

International Nuclear Information System (INIS)

Svoboda, V.; Merta, J.; Slach, J.

The effect is discussed of liquid sodium on the long-term properties of austenitic steels corresponding to the ASI 304 and ASI 316 types, mainly of steel CSN 17348. The choice is described of test specimens and of the experimental sodium test equipment. Testing was carried out using the so-called indirect method, i.e., the liquid sodium effect was assessed using the results of creep tests of two groups of specimens, one exposed to sodium and the other to the inert argon atmosphere. Otherwise the tests proceeded under identical conditions. The sodium stand had been manufactured for exposure of test specimens to liquid sodium. The morphology of specimen surfaces was studied by the JSN-50A electron microscope. The results of testing steel CSN 17348-AKV EXTRA S exposed to liquid sodium containing 10 ppm of oxygen at a temperature of 550 degC showed a significant sodium effect on the basic mechanical properties, on long-term creep strength and on the metallurgical properties. (Oy)

Lessons learned from the design of chemical space networks and opportunities for new applications

Science.gov (United States)

Vogt, Martin; Stumpfe, Dagmar; Maggiora, Gerald M.; Bajorath, Jürgen

2016-03-01

The concept of chemical space is of fundamental relevance in chemical informatics and computer-aided drug discovery. In a series of articles published in the Journal of Computer- Aided Molecular Design, principles of chemical space design were evaluated, molecular networks proposed as an alternative to conventional coordinate-based chemical reference spaces, and different types of chemical space networks (CSNs) constructed and analyzed. Central to the generation of CSNs was the way in which molecular similarity relationships were assessed and a primary focal point was the network-based representation of biologically relevant chemical space. The design and comparison of CSNs based upon alternative similarity measures can be viewed as an evolutionary path with interesting lessons learned along the way. CSN design has matured to the point that such chemical space representations can be used in practice. In this contribution, highlights from the sequence of CSN design efforts are discussed in context, providing a perspective for future practical applications.

Cloud Computing Services for Seismic Networks

Science.gov (United States)

Olson, Michael

This thesis describes a compositional framework for developing situation awareness applications: applications that provide ongoing information about a user's changing environment. The thesis describes how the framework is used to develop a situation awareness application for earthquakes. The applications are implemented as Cloud computing services connected to sensors and actuators. The architecture and design of the Cloud services are described and measurements of performance metrics are provided. The thesis includes results of experiments on earthquake monitoring conducted over a year. The applications developed by the framework are (1) the CSN---the Community Seismic Network---which uses relatively low-cost sensors deployed by members of the community, and (2) SAF---the Situation Awareness Framework---which integrates data from multiple sources, including the CSN, CISN---the California Integrated Seismic Network, a network consisting of high-quality seismometers deployed carefully by professionals in the CISN organization and spread across Southern California---and prototypes of multi-sensor platforms that include carbon monoxide, methane, dust and radiation sensors.

Lessons learned from the design of chemical space networks and opportunities for new applications.

Science.gov (United States)

Vogt, Martin; Stumpfe, Dagmar; Maggiora, Gerald M; Bajorath, Jürgen

2016-03-01

The concept of chemical space is of fundamental relevance in chemical informatics and computer-aided drug discovery. In a series of articles published in the Journal of Computer-Aided Molecular Design, principles of chemical space design were evaluated, molecular networks proposed as an alternative to conventional coordinate-based chemical reference spaces, and different types of chemical space networks (CSNs) constructed and analyzed. Central to the generation of CSNs was the way in which molecular similarity relationships were assessed and a primary focal point was the network-based representation of biologically relevant chemical space. The design and comparison of CSNs based upon alternative similarity measures can be viewed as an evolutionary path with interesting lessons learned along the way. CSN design has matured to the point that such chemical space representations can be used in practice. In this contribution, highlights from the sequence of CSN design efforts are discussed in context, providing a perspective for future practical applications.

Fire extinguishing of electrical equipment under voltage at nuclear power plants

International Nuclear Information System (INIS)

Capek, Josef

2009-01-01

Fire extinguishing on equipment that is under voltage is always hazardous. Conventional fire fighting equipment applicable to this task includes powder and gas extinguishers, which, however, have some drawbacks. Therefore, attention has been increasingly devoted to high-pressure fire extinguishing, whose assets include better heat removal as compared to a full water flow where the majority of the water runs off without any cooling effect. This article describes the testing of some types and combinations of extinguishing techniques and their interpretation based on earth-leakage current measurement and determination of a safe distance for fire extinguishing. Methodology described in CSN IEC 60-1:1994 and CSN EN 3-7:2004 was applied. To meet the criterion, none of the tests was to exhibit an earth-leakage current higher than 0.5 mA. In the accredited laboratory test room setup, 3 extinguishing equipment arrangements proved to extinguish fire on electrical equipment under voltage at a safe distance of 1 m (or 3 m). (orig.)

COMPORTAMENTO DA Cordia africana Lam. CULTIVADA EM SOLO CONTAMINADO POR METAIS PESADOS E TRATADO COM MATERIAIS AMENIZANTES

Directory of Open Access Journals (Sweden)

Ana Carolina Callegario Pereira

2013-01-01

Full Text Available This study aimed to evaluate the remediation of two soils contaminated with heavy metals from soil excavations, located near the port of Itaguaí, through the techniques of chemical immobilization and phytostabilization using the species Cordia africana. The data were collected in the ore courtyard from ‘Companhia Siderúgica Nacional’ (CSN, in the port of Itaguaí, Rio de Janeiro state. In order to reduce the solubility of heavy metals present in these substrates, two industrial waste products produced by CSN were used as ameliorating products, the steelmaking slag and the mill scale, in different concentrations. The plant species was considered with potential to be used in programs of phytostabilization, due to its heavy metal tolerance studied and to high accumulation of such elements in roots and stem. In the substrate of low combination, the lowest accumulation of zinc and cadmium in stems and leaves occurred with the use of 4% of soothing. In the substrate of high accumaltion it was 6%.

Molecular characterization of a long range haplotype affecting protein yield and mastitis susceptibility in Norwegian Red cattle

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Hayes Ben J

2011-08-01

Full Text Available Abstract Background Previous fine mapping studies in Norwegian Red cattle (NRC in the region 86-90.4 Mb on Bos taurus chromosome 6 (BTA6 has revealed a quantitative trait locus (QTL for protein yield (PY around 88 Mb and a QTL for clinical mastitis (CM around 90 Mb. The close proximity of these QTLs may partly explain the unfavorable genetic correlation between these two traits in NRC. A long range haplotype covering this region was introduced into the NRC population through the importation of a Holstein-Friesian bull (1606 Frasse from Sweden in the 1970s. It has been suggested that this haplotype has a favorable effect on milk protein content but an unfavorable effect on mastitis susceptibility. Selective breeding for milk production traits is likely to have increased the frequency of this haplotype in the NRC population. Results Association mapping for PY and CM in NRC was performed using genotypes from 556 SNPs throughout the region 86-97 Mb on BTA6 and daughter-yield-deviations (DYDs from 2601 bulls made available from the Norwegian dairy herd recording system. Highest test scores for PY were found for single-nucleotide polymorphisms (SNPs within and surrounding the genes CSN2 and CSN1S2, coding for the β-casein and αS2-casein proteins. High coverage re-sequencing by high throughput sequencing technology enabled molecular characterization of a long range haplotype from 1606 Frasse encompassing these two genes. Haplotype analysis of a large number of descendants from this bull indicated that the haplotype was not markedly disrupted by recombination in this region. The haplotype was associated with both increased milk protein content and increased susceptibility to mastitis, which might explain parts of the observed genetic correlation between PY and CM in NRC. Plausible causal polymorphisms affecting PY were detected in the promoter region and in the 5'-flanking UTR of CSN1S2. These polymorphisms could affect transcription or translation of

Desempenho de diferentes grupos genéticos de bovinos de corte em confinamento Performance evaluation of different beef cattle genetic groups under feedlot

Directory of Open Access Journals (Sweden)

Kepler Euclides Filho

2003-10-01

Full Text Available Foram utilizadas informações provenientes de 188 animais, pertencentes a dez grupos genéticos, avaliados em confinamento. Para as análises dos dados, os animais foram agrupados em três subconjuntos considerando-se idade, sexo e dieta recebida. Os subconjuntos analisados foram: 1 animais inteiros de sobreano recebendo a dieta "a": 39 Nelore (N, 12 Brangus (BR, 8 1/2 Simental-1/2 Nelore (SN, 8 1/2 Caracu-1/2 Nelore (CCN, 21 1/2 Valdostana-1/2 Nelore (VAN; 2 animais inteiros desmamados recebendo a dieta "b": 12 N, 12 1/2 Canchim-1/4 Angus-1/4 Nelore (CAN, 16 1/2 Canchim-1/4 Simental-1/4 Nelore (CSN, 12 1/2 Braford-1/2 Brangus (BDBR, 12 1/2 Braford-1/4 Angus-1/4 Nelore (BDAN, 7 1/2 Brahman-1/4 Angus-1/4 Nelore (BHAN; 3 fêmeas desmamadas recebendo a dieta "b" em duas formulações, uma em que o concentrado representou 30% da MS e o outro, em que o concentrado correspondeu a 50% da MS total. Neste caso, a análise incluiu 29 fêmeas, 15 CAN e 14 CSN. Para os animais dos subconjuntos 1 e 2, o concentrado foi fornecido para atender 50% da MS total da dieta. Os animais do subconjunto 1 apresentaram desempenhos semelhantes, com ganho de peso diário médio igual a 1,60 kg/dia e com conversão alimentar igual a 6,36 kg de MS ingerida/kg de ganho de peso. Para o ganho de peso diário médio e para a conversão alimentar, somente foram observadas diferenças entre os animais do subconjunto 2. O maior ganho de peso diário médio foi observado para os animais CSN (1,69 kg/dia e as melhores conversões alimentares foram verificadas para os animais CSN e BHAN (4,76 kg de MS ingerida/kg de ganho de peso e 4,67 kg de MS ingerida/kg de ganho de peso, respectivamente. Para o subconjunto 3 não houve diferenças entre os grupos genéticos, mas a formulação da dieta apresentou efeitos significativos importantes, especialmente, para conversão alimentar. Os animais da formulação com menor teor de concentrado apresentaram melhor conversão alimentar (5,58 kg

Mala praxis médica en el quirófano

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Tania Amores Agulla

Full Text Available La mala praxis médica constituye actualmente un problema global de salud, incluso en los mejores centros hospitalarios del mundo. Se consultaron 26 referencias bibliográficas nacionales e internacionales acerca del tema con el objetivo de determinar el estado actual de los errores médicos en el quirófano. El ejercicio de la medicina tiene riesgos inherentes y la naturaleza humana hace imposible que el hombre sea infalible. Los tipos de errores más frecuentes en la práctica médica son: administración equívoca de medicamentos, diagnósticos inciertos, fallas técnicas (procedimientos insuficientes, incompletos y/o incorrectos y demora en el salón de operaciones. Las causas más frecuentes engloban el cansancio, la prisa, falta de conocimientos, entre otras. La prevención es posible y son numerosas las estrategias aplicadas por los diferentes sistemas de salud: estimular el trabajo en equipo, fortalecer la capacitación del médico y personal paramédico, evitar confiar en la memoria usando listas de chequeo, estandarizar procedimientos y protocolos, crear la cultura del reporte voluntario de errores. El error debe ser utilizado como una oportunidad para aprender, para mejorar la calidad en la atención y por ende, la seguridad de los enfermos.

Optimización en Tiempo Real utilizando la Metodología de Adaptación de Modificadores

Directory of Open Access Journals (Sweden)

T. Rodríguez-Blanco

2018-03-01

Full Text Available La gestión óptima de las plantas de proceso normalmente se lleva a cabo en una capa de optimización en tiempo real (Real Time Optimization, RTO que actúa sobre la capa de control y que toma decisiones considerando objetivos económicos en base a un  modelo del proceso, normalmente estacionario. Sin embargo, dicha operación óptima no está garantizada debido a la presencia de incertidumbre entre el modelo usado para la toma de decisiones y el proceso real. Con la idea de conducir el proceso a su punto de operación óptimo usando un modelo que se sabe incierto o erróneo, surge la metodología de adaptación de modificadores (Modifier Adaptation o MA. En dicha metodología, el problema de optimización económica de la capa RTO es modificado mediante unos términos correctores, conocidos como modificadores, estimados a partir de medidas de la planta, con el objetivo de conducir el proceso a su punto de operación óptimo. El presente artículo hace una revisión de las técnicas desarrolladas hasta el momento dentro de la metodología MA analizando sus características y modos de implementación.

CONFIGURACIONES DE SUJETO EN LA MODERNIDAD LATINOAMERICANA: EL CASO DE PERÚ A INICIOS DEL SIGLO XX

Directory of Open Access Journals (Sweden)

Kathya Araujo

2010-04-01

Full Text Available Este texto se aproxima al estudio del sujeto y de los lazos sociales en nuestra región a partir del análisis del caso del Perú en las primeras décadas del siglo XX. Lo hace tomando apoyo en la noción de configuraciones de sujeto como operador analítico y usando como corpus textos autobiográficos en cuanto se considera que ellos son una vía privilegiada para este tipo de estudios. El texto se inicia con una presentación de los fundamentos teóricos y metodológicos que lo sustentan y, posteriormente, discute tres rasgos sobresalientes de las configuraciones de sujeto encontradas para el caso peruano en el momento histórico estudiado y lo que ellos revelan sobre el lazo social.This paper approaches the study of the subject and the social bond in the case of Peru in the first three decades of the 20th century. It uses as analytical operator the notion of subject configurations and it is based upon the analysis of autobiographical texts. The text begins with the presentation of its theoretical and methodological foundations and then goes on to discuss three of the main features of the subject configurations founding of these texts, and their meaning for the understanding of the social bond.

ALGORITMO PARA EL ANÁLISIS PROBABILÍSTICO EN SISTEMAS DE DISTRIBUCIÓN CON GENERACIÓN DISTRIBUÍDA

Directory of Open Access Journals (Sweden)

CESAR AUGUSTO PEÑUELA MENESES

2011-01-01

Full Text Available Este artículo presenta un algoritmo eficiente para el análisis probabilístico de sistemas de distribución trifásicos desbalanceados con conexión de generadores distribuidos (sistemas levemente enmallados. Este algoritmo hace uso de la técnica del Método Estimado de Dos Puntos para el cálculo del comportamiento probabilístico de las variables aleatorias del sistema. Adicionalmente, y con el fin de explotar eficientemente las características topológicas de la red, el análisis determinístico de las variables de estado es realizado por medio de un Flujo de carga Radial Basado en Compensación (FCRBC. Para el tratamiento de la generacióndistribuida, se propone una estrategia para incorporar dentro del FCRBC un modelo simplificado del generador junto con un control de las variables de despacho en el punto de conexión con la red. De este modo, el nodo con generación distribuida puede ser modelado como un nodoPV, o nodo PQ, dependiendo del modo de control y de las condiciones operativas del generador. Para validar la eficiencia del algoritmo propuesto es usado el sistema de prueba IEEE de 37 nodos. Los resultados probabilísticos son comparados con los obtenidos usando el método de Monte Carlo.

El acceso al saber requiere aplicar organización y representación del conocimiento

Directory of Open Access Journals (Sweden)

Tania Peña Vera

2010-01-01

Full Text Available Investigación documental que explica la importancia de los procesos de organización y representación del conocimiento (ORC en el acceso expedito a las fuentes de información y conocimiento. La explicación se ofrece desde un enfoque racional, usando el análisis y la deducción, y abordando el tema desde lo general hacia lo específico. A partir de la reflexión sobre la necesidad humana de conocer y estar informado, y las dificultades que origina el crecimiento exponencial de los volúmenes de contenidos digitales y en formato físico, se hace una caracterización histórica y actual de la ORC, resaltando la incidencia que las tecnologías de información y comunicación tienen en los esquemas de sistematización y difusión del conocimiento, además de los cambios que se vienen dando en las estructuras del pensamiento humano, en los patrones de acceso a la información y en la misma ORC. Se concluye que la ORC crea los medios para erradicar la brecha informativa y democratizar el conocimiento, y se recomienda ahondar tanto en su construcción teórica como en el mejoramiento de sus aspectos prácticos.

Nepohualtzitzin: un modelo matemático de cualidad

Directory of Open Access Journals (Sweden)

Everardo Lara González

2010-08-01

Full Text Available En Mesoamérica, el pueblo náhuatl crea un modelo matemático figurativo de cualidad, donde pretende identificar y abstraer los elementos esenciales de un sistema que concentra la analogía funcional del pensamiento que guía a los pueblos de nuestro continente: una bandera, una pluma y una bolsa, figurassimbólicas utilizadas por todos los pueblos indios del continente para representar sus valores.Consideramos que tales valores también se sintetizan en la palabra náhuatl: Nepohualtzitzin (Ne: la persona. Pohualli: cuenta. Tzitzin: trascender, el cual es un instrumento de cálculo. La idea sustancial es: La persona que tiene el conocimiento de la cuenta de la simplicidad de la armonía para trascender al origen de lacreación. Hemos tenido varias experiencias educativas en diversos países, en los cuales utilizamos el Nepohualtzitzincomo recurso didáctico que hace posible el desarrollo de habilidades integrales con un potencial fuerte para incorporar la metáfora indígena y algunas reflexiones históricas.Seguimos usando el Nepohualtzitzin como un instrumento de cálculo del sistema vigesimal (adaptándolo también al sistema decimal porque nos da la conciencia y el conocimiento de las cuentas para trascender,propiciando el desarrollo y la destreza de pensamiento de nuestros hijos.

Exergoeconomic optimization of tetra-combined trigeneration system

Directory of Open Access Journals (Sweden)

Juan Carlos Burbano J.

2015-01-01

Full Text Available Se pretende obtener configuraciones óptimas de sistemas de trig eneración para satisfacer demandas de electricidad y cargas tér micas de calentamiento y enfriamiento, evaluando el impacto de los costo s de producción de electricidad, vapor y agua fría. Un sistema de trigeneración produce electricidad, calor y enfriamiento usando esa electrici dad o calor disponible. Se hace énfasis en sistemas que usan re frigeración por absorción, incluyendo uno que usa refrigeración hibrida de abso rción eyectocompresión, llamado sistema tetracombinado de tri generación. La evaluación del desempeño de los sistemas se lleva a cabo med iante el análisis exergético y exergoeconómico de las alternati vas propuestas para determinar la eficiencia exergética y los costos exergétic os de la producción de las utili dades del sistema. Se usó el m étodo de Algoritmos Genéticos para la optimización de las plantas de trigeneración. La optimización muestra beneficios importantes en los costos e xergéticos de los productos por medio de la maximización de la eficiencia exergét ica de los diferentes sistemas.

Redundant filtration system of the fuel buildings,units 1 and 2 Almaraz NPP

International Nuclear Information System (INIS)

Lopez Tanco, J.

2011-01-01

The project redundant filtering fuel buildings in units 1 and 2 of Almaraz NPP, will compliance to the requirements established in the complementary technical instructions to the authorization of exploitation of Almaraz NPP, established by the CSN and will consist of the installation of a new filtration unit.

DSS1/Sem1, a multifunctional and intrinsically disordered protein

DEFF Research Database (Denmark)

Kragelund, Birthe Brandt; Schenstrøm, Signe Marie; Rebula, Caio A.

2016-01-01

DSS1/Sem1 is a versatile intrinsically disordered protein. Besides being a bona fide subunit of the 26S proteasome, DSS1 associates with other protein complexes, including BRCA2-RPA, involved in homologous recombination; the Csn12-Thp3 complex, involved in RNA splicing; the integrator, involved...

Parámetros genéticos para la persistencia de la lactación en vacas Siboney usando modelos de regresión aleatoria

Directory of Open Access Journals (Sweden)

Dianelys González-Peña Fundora

2011-01-01

Full Text Available Con el objetivo de estimar los valores de heredabilidad y las correlaciones genéticas entre cinco medidas de persistencia usando un modelo de regresión aleatoria con polinomios de Legendre, se analizaron 17,034 registros de producción de leche del día del control de 2,086 vacas Siboney de Cuba (primera lactancia que parieron entre 1995 y 2003 en 50 hatos. Los estimados de heredabilidad para la persistencia de la lactación variaron de 0.18±0.02 a 0.29±0.02. Las correlaciones genéticas entre las diferentes medidas de persistencia oscilaron de -0.71 a 0.95. Las correlaciones genéticas entre la producción de leche en los distintos días del control, así como la producción acumulada hasta los 305 días de lactación (PL305 y las distintas medidas de persistencia tomaron valores de -0.06 hasta 0.11. Basado en los niveles de heredabilidad y en las correlaciones genéticas de las medidas de persistencia con la PL305, se concluye que es factible efectuar la selección conjunta para la PL305 y persistencia de la lactación en el ganado Siboney utilizando la diferencia en el área bajo la curva entre el tercio final de la lactación (día 201 al 300 y el tercio inicial del día 1 al 100, (sumatoria de la contribución de cada día, en el periodo de los 61 a 280 días de lactación, como una desviación de la producción en el día 60 como medidas de persistencia.

Realistic retrospective dose assessments to members of the public around Spanish nuclear facilities

Energy Technology Data Exchange (ETDEWEB)

Jimenez, M.A., E-mail: majg@csn.es [Consejo de Seguridad Nuclear (CSN), Pedro Justo Dorado Dellmans 11, E-28040 Madrid (Spain); Martin-Valdepenas, J.M.; Garcia-Talavera, M.; Martin-Matarranz, J.L.; Salas, M.R.; Serrano, J.I.; Ramos, L.M. [Consejo de Seguridad Nuclear (CSN), Pedro Justo Dorado Dellmans 11, E-28040 Madrid (Spain)

2011-11-15

In the frame of an epidemiological study carried out in the influence areas around the Spanish nuclear facilities (ISCIII-CSN, 2009. Epidemiological Study of The Possible Effect of Ionizing Radiations Deriving from The Operation of Spanish Nuclear Fuel Cycle Facilities on The Health of The Population Living in Their Vicinity. Final report December 2009. Ministerio de Ciencia e Innovacion, Instituto de Salud Carlos III, Consejo de Seguridad Nuclear. Madrid. Available from: (http://www.csn.es/images/stories/actualidad{sub d}atos/especiales/epidemiologico/epidemiological{sub s}tudy.pdf)), annual effective doses to public have been assessed by the Spanish Nuclear Safety Council (CSN) for over 45 years using a retrospective realistic-dose methodology. These values are compared with data from natural radiation exposure. For the affected population, natural radiation effective doses are in average 2300 times higher than effective doses due to the operation of nuclear installations (nuclear power stations and fuel cycle facilities). When considering the impact on the whole Spanish population, effective doses attributable to nuclear facilities represent in average 3.5 x 10{sup -5} mSv/y, in contrast to 1.6 mSv/y from natural radiation or 1.3 mSv/y from medical exposures. - Highlights: > Most comprehensive dose assessment to public by nuclear facilities ever done in Spain. > Dose to public is dominated by liquid effluent pathways for the power stations. > Dose to public is dominated by Rn inhalation for milling and mining facilities. > Average annual doses to public in influence areas are negligible (10 {mu}Sv/y or less). > Doses from facilities average 3.5 x 10{sup -2} {mu}Sv/y per person onto whole Spanish population.

Monoclonal antibodies to hyphal exoantigens derived from the opportunistic pathogen Aspergillus terreus.

Science.gov (United States)

Nayak, Ajay P; Green, Brett J; Janotka, Erika; Hettick, Justin M; Friend, Sherri; Vesper, Steve J; Schmechel, Detlef; Beezhold, Donald H

2011-09-01

Aspergillus terreus has been difficult to identify in cases of aspergillosis, and clinical identification has been restricted to the broad identification of aspergillosis lesions in affected organs or the detection of fungal carbohydrates. As a result, there is a clinical need to identify species-specific biomarkers that can be used to detect invasive A. terreus disease. Monoclonal antibodies (MAbs) were developed to a partially purified preparation of cytolytic hyphal exoantigens (HEA) derived from A. terreus culture supernatant (CSN). Twenty-three IgG1 isotype murine MAbs were developed and tested for cross-reactivity against hyphal extracts of 54 fungal species. Sixteen MAbs were shown to be specific for A. terreus. HEA were detected in conidia, hyphae, and in CSN of A. terreus. HEA were expressed in high levels in the hyphae during early stages of A. terreus growth at 37°C, whereas at room temperature the expression of HEA peaked by days 4 to 5. Expression kinetics of HEA in CSN showed a lag, with peak levels at later time points at room temperature and 37°C than in hyphal extracts. Serum spiking experiments demonstrated that human serum components do not inhibit detection of the HEA epitopes by MAb enzyme-linked immunosorbent assay (ELISA). Immunoprecipitation and proteomic analysis demonstrated that MAbs 13E11 and 12C4 immunoprecipitated a putative uncharacterized leucine aminopeptidase (Q0CAZ7), while MAb 19B2 recognized a putative dipeptidyl-peptidase V (DPP5). Studies using confocal laser scanning microscopy showed that the uncharacterized leucine aminopeptidase mostly localized to extracellular matrix structures while dipeptidyl-peptidase V was mostly confined to the cytoplasm.

Realistic retrospective dose assessments to members of the public around Spanish nuclear facilities

International Nuclear Information System (INIS)

Jimenez, M.A.; Martin-Valdepenas, J.M.; Garcia-Talavera, M.; Martin-Matarranz, J.L.; Salas, M.R.; Serrano, J.I.; Ramos, L.M.

2011-01-01

In the frame of an epidemiological study carried out in the influence areas around the Spanish nuclear facilities (ISCIII-CSN, 2009. Epidemiological Study of The Possible Effect of Ionizing Radiations Deriving from The Operation of Spanish Nuclear Fuel Cycle Facilities on The Health of The Population Living in Their Vicinity. Final report December 2009. Ministerio de Ciencia e Innovacion, Instituto de Salud Carlos III, Consejo de Seguridad Nuclear. Madrid. Available from: (http://www.csn.es/images/stories/actualidad_datos/especiales/epidemiologico/epidemiological_study.pdf)), annual effective doses to public have been assessed by the Spanish Nuclear Safety Council (CSN) for over 45 years using a retrospective realistic-dose methodology. These values are compared with data from natural radiation exposure. For the affected population, natural radiation effective doses are in average 2300 times higher than effective doses due to the operation of nuclear installations (nuclear power stations and fuel cycle facilities). When considering the impact on the whole Spanish population, effective doses attributable to nuclear facilities represent in average 3.5 x 10 -5 mSv/y, in contrast to 1.6 mSv/y from natural radiation or 1.3 mSv/y from medical exposures. - Highlights: → Most comprehensive dose assessment to public by nuclear facilities ever done in Spain. → Dose to public is dominated by liquid effluent pathways for the power stations. → Dose to public is dominated by Rn inhalation for milling and mining facilities. → Average annual doses to public in influence areas are negligible (10 μSv/y or less). → Doses from facilities average 3.5 x 10 -2 μSv/y per person onto whole Spanish population.

Process of licensing nuclear facilities (resume from the Spanish National Report for the Joint Convention, 2005)

International Nuclear Information System (INIS)

Prieto, N.

2007-01-01

The process of licensing both nuclear and radioactive facilities is governed by the Regulation on Nuclear and Radioactive Facilities (Span. Reglamento de Instalaciones Nucleares y Radiactivas, RINR), approved by Royal Decree 1836/1999, of 3 December. According to the RINR, these authorizations are granted by the Ministry of Industry, Tourism and Trade (Span. Ministerio de Industria, Turismo y Comercio, MITYC), to which the corresponding requests should be addressed, along with the documentation required in each case, The MITYC sends a copy of each request and accompanying documentation to the Nuclear Safety Council (Span. Consejo de Seguridad Nuclear, CSN) for its mandatory report.) The CSN reports are mandatory and binding, both were negative or withholding in nature with respect to the request and, when positive, as regards the conditions established. On receiving the report from the CSN, and following whatever decisions or further reports might be required in each case, the MITYC will adopt the appropriate resolution. System for the licensing of nuclear facilities. According to the definitions included in the RINR, the following are nuclear facilities: - Nuclear power plants. - Nuclear reactors. - Manufacturing facilities using nuclear fuels to produce nuclear substances and those at which nuclear substances are treated. - Facilities for the permanent storage of nuclear substances. In compliance with the RINR, the nuclear facilities require different permits or administrative authorizations for their operation, these being the preliminary or site authorization, the construction permit, the operating permit, the authorization for modification and the dismantling permit. The procedure for the awarding of each of these authorizations is regulated by the Regulation itself and is briefly described below. (author)

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

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Hofmann Kay

2002-09-01

Full Text Available Abstract Background Three macromolecular assemblages, the lid complex of the proteasome, the COP9-Signalosome (CSN and the eIF3 complex, all consist of multiple proteins harboring MPN and PCI domains. Up to now, no specific function for any of these proteins has been defined, nor has the importance of these motifs been elucidated. In particular Rpn11, a lid subunit, serves as the paradigm for MPN-containing proteins as it is highly conserved and important for proteasome function. Results We have identified a sequence motif, termed the MPN+ motif, which is highly conserved in a subset of MPN domain proteins such as Rpn11 and Csn5/Jab1, but is not present outside of this subfamily. The MPN+ motif consists of five polar residues that resemble the active site residues of hydrolytic enzyme classes, particularly that of metalloproteases. By using site-directed mutagenesis, we show that the MPN+ residues are important for the function of Rpn11, while a highly conserved Cys residue outside of the MPN+ motif is not essential. Single amino acid substitutions in MPN+ residues all show similar phenotypes, including slow growth, sensitivity to temperature and amino acid analogs, and general proteasome-dependent proteolysis defects. Conclusions The MPN+ motif is abundant in certain MPN-domain proteins, including newly identified proteins of eukaryotes, bacteria and archaea thought to act outside of the traditional large PCI/MPN complexes. The putative catalytic nature of the MPN+ motif makes it a good candidate for a pivotal enzymatic function, possibly a proteasome-associated deubiquitinating activity and a CSN-associated Nedd8/Rub1-removing activity.

Amino Groups of Chitosan Are Crucial for Binding to a Family 32 Carbohydrate Binding Module of a Chitosanase from Paenibacillus elgii*

Science.gov (United States)

Das, Subha Narayan; Wagenknecht, Martin; Nareddy, Pavan Kumar; Bhuvanachandra, Bhoopal; Niddana, Ramana; Balamurugan, Rengarajan; Swamy, Musti J.; Moerschbacher, Bruno M.; Podile, Appa Rao

2016-01-01

We report here the role and mechanism of specificity of a family 32 carbohydrate binding module (CBM32) of a glycoside hydrolase family 8 chitosanase from Paenibacillus elgii (PeCsn). Both the activity and mode of action of PeCsn toward soluble chitosan polymers were not different with/without the CBM32 domain of P. elgii (PeCBM32). The decreased activity of PeCsn without PeCBM32 on chitosan powder suggested that PeCBM32 increases the relative concentration of enzyme on the substrate and thereby enhanced enzymatic activity. PeCBM32 specifically bound to polymeric and oligomeric chitosan and showed very weak binding to chitin and cellulose. In isothermal titration calorimetry, the binding stoichiometry of 2 and 1 for glucosamine monosaccharide (GlcN) and disaccharide (GlcN)2, respectively, was indicative of two binding sites in PeCBM32. A three-dimensional model-guided site-directed mutagenesis and the use of defined disaccharides varying in the pattern of acetylation suggested that the amino groups of chitosan and the polar residues Glu-16 and Glu-38 of PeCBM32 play a crucial role for the observed binding. The specificity of CBM32 has been further elucidated by a generated fusion protein PeCBM32-eGFP that binds to the chitosan exposing endophytic infection structures of Puccinia graminis f. sp. tritici. Phylogenetic analysis showed that CBM32s appended to chitosanases are highly conserved across different chitosanase families suggesting their role in chitosan recognition and degradation. We have identified and characterized a chitosan-specific CBM32 useful for in situ staining of chitosans in the fungal cell wall during plant-fungus interaction. PMID:27405759

Abundancias químicas de estrellas de Mercurio-Manganeso obtenidas con espectros EBASIM

Science.gov (United States)

Pintado, O. I.; Adelman, S. J.

Se determinan las abundancias químicas de estrellas de HgMn usando espectros obtenidos con EBASIM en CASLEO en un rango de longitud de onda comprendido entre los 400 y 890 nm. Los valores iniciales de temperatura efectiva y gravedad superficial se calculan con la fotometría uvbyβ. Las abundancias se calculan usando WIDTH9 y SYNTHE. Los resultados se comparan análisis realizados por los autores usando espectros obtenidos con el espectrógrado REOSC del CASLEO, el espectrógrafo echelle del Telescopio Anglo-Australiano y el espectrógrafo Coudé del Dominion Astrophysical Observatory.

¿Qué hace comunitaria a una radio comunitaria?

Directory of Open Access Journals (Sweden)

José Ignacio López Vigil

2015-01-01

Full Text Available En Canadá nacieron con el nombre de radios comunitarias . En América Latina, la variedad de los apellidos da cuenta de la riqueza de las experiencias: LIBRES en Brasil,PARTICIPATIVAS en Nicaragua, POPULARES en el Ecuador.El autor señala que cambia el traje pero no el monje. El desafío de estas emisoras es similar: democratizar la palabra para hacer más democrática esta sociedad injusta.Afirma que las radios comunitarias no son periféricas ni provisionales. La radio comunitaria se desarrolla de igual manera en una gran capital o en un caserío campesino, solo necesita de una comunidad y sentencia que el dinero se necesita porque no solo quieren subsistir sino que también aspiran a ser empresas sólidas, autofinanciadas y rentables el uso de la publicidad comercial no define ni cambia su esencia.El trabajo que se desarrolla es para transformar las condiciones sociales , la calidad de vida de nuestros congéneres participación de los ciudadanos

Proceedings of the 30. Seminar of global energy balances and utilities; 24. Meeting of the producers and consumers of industrial gases. Energy efficiency for the future; Anais do 30. Seminario de balancos energeticos globais e utilidades; 24. Encontro de produtores e consumidores de gases industriais

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-12-11

Papers on energy balance are presented in these proceedings covering the industrial gases consumption, production, technology utilization and energy efficiency. Also presented the graphical and diagrams of the annual energetic balance of the ArcelorMittal Inox Brasil, ArcelorMittal Monlevade, ArcelorMittal Tubarao, CSN, Usiminas, Usiminas Cubatao and V and M do Brasil.

The ethics of research and development

International Nuclear Information System (INIS)

Munoz, E.

1997-01-01

The changes modern society is undergoing also affect the scientific world which must adapt to new forms of producing knowledge. The text of this article reproduces the lecture which the researcher Emilio Munoz recently gave at the CSN. advocating a model on which science, technology and society may act in harmony. (Author)

Regents' Review. Volume 10, Issue 4

Science.gov (United States)

Nevada System of Higher Education, 2008

2008-01-01

This issue of the newsletter includes: (1) CSN's Automotive Program: Training Tomorrow's Workforce Today; (2) Chair's Corner; (3) A Nation at Risk (editorial); (4) UNHSS Moves Forward With First Private Gift; and (5) Nevada Higher Education in the News. [Document published by the Board of Regents of the Nevada System of Higher Education.

Mapeo curvas típicas demanda de energía eléctrica del sector residencial, comercial e industrial de la ciudad de Medellín, usando redes neuronales artificiales y algoritmos de interpolación

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Héctor Tabares

2008-01-01

Full Text Available Uno de los principales problemas para modelar el consumo de energía eléctrica en un lugar determinado, consiste en la extracción del conocimiento cuando éste se encuentra almacenado en grandes volúmenes de información como, por ejemplo, registros históricos. De acuerdo con esta representación, cada hecho ocurrido y registrado está compuesto por una pareja de componentes (t, P en donde t representa el tiempo en el que se registro la muestra y P representa la potencia eléctrica consumida en ese instante. El registro diario cuenta con N casos que representa cada una de las parejas de estímulo-respuesta conocidas. El objetivo de este trabajo consiste en hallar una función que permita mapear el vector de variables de entrada t al vector de variables de salida P. donde F es una función cualquiera, en este caso el consumo de energía eléctrica. Su modelamiento con Redes Neuronales Artificiales (RNA es un Perceptron Multi Capa (PMC. Otra forma de modelarlo es usando Algoritmos de Interpolación (AI.

Evaluación del impacto de la vacuna contra rotavirus en Colombia usando métodos rápidos de evaluación

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Karol Cotes

2013-10-01

Full Text Available OBJETIVO: Estimar la efectividad de la vacuna monovalente antirrotavírica para prevenir la hospitalización por enfermedad diarreica aguda en niños menores de 2 años en cinco ciudades de Colombia. MÉTODOS: Se realizó una encuesta poblacional sobre una muestra probabilística de niños mayores de 2 meses y menores de 24 meses de edad en cinco ciudades de Colombia (Barranquilla, Bogotá, Cali, Cartagena y Riohacha en el período de agosto a octubre de 2010. La vacuna fue introducida en el Programa Ampliado de Inmunizaciones en enero de 2009. Se estimaron las coberturas de vacunación contra rotavirus por grupos de edad y la incidencia acumulada de hospitalización por diarrea severa, y se evaluó la magnitud de la asociación entre la vacunación con una o dos dosis de vacuna antirrotavírica y la hospitalización por diarrea, utilizando la razón de probabilidades (RP ajustada por edad y otros factores de importancia epidemiológica. La efectividad de la vacunación se estimó usando la expresión 1 - RP. RESULTADOS: La cobertura de vacunación con una dosis de vacuna fue de 87,3%. En los 12 meses previos a la encuesta 43,2% (1 453 niños de menores de 24 meses presentaron diarrea, y de ellos, 5,2% (174 niños fueron hospitalizados por esta causa. La efectividad de dos dosis de vacuna antirrotavírica para prevenir la hospitalización por diarrea severa fue de 68% (intervalo de confianza de 95%: 55%-77%. CONCLUSIONES: La vacunación contra rotavirus en Colombia protege contra la hospitalización por diarrea por cualquier causa. El uso de encuestas transversales se mostró adecuado para evaluar rápidamente la efectividad de un programa de vacunación con una nueva vacuna.

Monitoring of the operation of a nuclear power station with design problems in an importing country: The Almaraz power station

International Nuclear Information System (INIS)

Reig, J.

1984-01-01

The purpose of this paper is to describe the regulatory activities carried out in Spain as a result of the design problem occurring in the steam generators during operation of Unit I of the Almaraz nuclear power station. First, a brief introduction is given to the operating history and characteristics of Unit I of Almaraz. Particular attention is paid to the specific licences issued subsequent to commercial operation which place limitations on the operation of the station and to the operational incidents of which the Nuclear Safety Council (CSN) has been notified. Next, a description is provided of the safety evaluation carried out by the CSN. Three aspects merit particular attention: methodology, evaluation and conclusions. The methodology applied by an importing country is normally based on that of the country of origin of the design, so that the overall evaluation by the NRC has been considered sufficiently representative of aspects specific to the Almaraz power station. In this regard the importance of international collaboration is clearly seen as a principal instrument for performing the evaluation. In the evaluation a distinction is made between general and specific aspects and between inspection programmes and quality assurance requirements. In addition, the conclusions leading to the requirement of the imposition of additional limitations on the operating licence are stated. Apart from the safety evaluation carried out by the CSN, other regulatory activities have been performed over this two-year period. These activities, which include site inspections, audits of the principal supplier company, other independent calculations and so on, are described. Lastly, the paper refers to the lessons learned from the operation of the above-mentioned unit, which are immediately applicable to other Spanish nuclear power stations. (author)

Harmonization of the Spanish radiation protection education and training system: educational specialized portal

International Nuclear Information System (INIS)

Marco Arboli, Marisa; Rodriguez Suarez, M.; Villarroel Gonzalez Elipe, R.; Rodriguez Marti, M.

2008-01-01

Full text: This paper shows the educational project developed by the Spanish Regulatory Body (CSN) and CIEMAT. The Radiation Protection Training and Education Portal is included in the framework of the regulated training system in Spain. The project is available on the CSN web site 'www.csn.es'. The main objective of this specialized portal is to provide the necessary mechanisms for standardization of the radiation protection knowledge and to provide training tools. One of the priorities of this project is to spread in Latino America the efforts of a big group of professionals made in the past years on education and training. The initiative also aims to collaborate and share resources. The web site is used for delivery of education content. The RP E and T Portal provides training material for course organizers, trainers and professionals involved. The project includes training tools for sixteen courses based in the standard syllabus content in the Spanish regulations. The courses have been prepared in a modular approach with specific modules focused in medical and industrial applications and prepared taking into account the different target groups and common levels. Each one of the modules includes learning objectives, syllabus, training schedule, theoretical lessons and practical sessions guidance, visual aids for trainers and test and questions to be used as self-evaluation. The training packages cover the initial training programmes needed by supervisors and operators of radioactive facilities in different areas of expertise including diagnostic radiology. The tasks in each of the modules have been designed to develop specific competence. More than 40 recognized experts have participated in this useful open project and their contribution to the training material offer important results and based on their experience having special attention on the quality of the material. (author)

Prevalência e fatores associados à infecção pelo Mycobacterium tuberculosis entre agentes comunitários de saúde no Brasil, usando-se a prova tuberculínica

Directory of Open Access Journals (Sweden)

Wesley Pereira Rogerio

2015-10-01

Full Text Available Resumo Este artigo tem por objetivo determinar a prevalência e os fatores associados à infecção latente pelo Mycobacterium tuberculosis entre agentes comunitários de saúde (ACS, usando dois pontos de corte da prova tuberculínica 5mm e 10mm. Trata-se de estudo transversal, com dados coletados sobre sexo, idade, cicatriz de BCG, prova tuberculínica (PT anterior, tempo que trabalha na profissão de ACS, atuar em unidade básica de saúde (UBS, ter tido contato intradomiciliar com tuberculose (TB, usar álcool, ser fumante e apresentar comorbidades. Para controle de variáveis de confusão e estimativa da medida de efeito (OR, foi empregada a regressão logística. Aplicou-se PT, com leitura após 48-72 horas. As prevalências foram de 57,88% e 37,3%, respectivamente, para 5mm e 10mm. Manteve-se associada à positividade para o ponto de corte de 10mm a condição de trabalhar em UBS com Programa de Controle de Tuberculose (PCT implementado e já ter tido contato intradomiciliar com TB. Já para o ponto de corte de 5mm, trabalhar em UBS com PCT e implementado. São necessárias ações de conscientização nos municípios e fortalecimento das ações de educação permanente sobre a temática.

Solución a un problema estático en un área con topografía abrupta usando una velocidad de reemplazamiento variable

Directory of Open Access Journals (Sweden)

Castillo López Luis Antonio

2002-08-01

calculate with variable velocity is proposed.

This method have been development in the processing data in areas with irregular surface. For instance, Piedemonte Llanero. The software calculation is ProMAX, algorithm Gauss-Sediel.

Teniendo en cuenta que para poder obtener una buena imagen del subsuelo, es necesario que las soluciones estáticas sean las mas acertadas posibles en la etapa inicial del procesamiento, y no gastar tiempo en ensayos con procesos mas sofisticados, sin tener resuelto el problema estático, se propone implantar un método de procesamiento usando un modelo de velocidad de reemplazamiento variable en el cálculo de la solución estática. Se pretende explicar que el valor de la velocidad de reemplazamiento influye notoriamente en la imagen de la estructura, la cual puede verse deformada en gran magnitud. Tambien puede ser cuestionado cómo ha sido asignado este valor de manera constante en los proyectos, dando más importancia al amarre con áreas cercanas que a la solución misma del problema estático.

Se mostrara un estudio en que se emplea una serie de datos reales procesados a partir de un modelo de velocidad de reemplazamiento variable y otra con un modelo de velocidad constante, las que -al ser comparadas y analizadas- dan como resultado grandes contrastes en las imageries obtenidas.

Este método se ha ido desarrollando durante el procesamiento de

Analysis of the behavior of irradiated BWR fuel rod in storage dry conditions; Analisis del comportamiento de una barra combustible irradiada BWR en condiciones de almacenamiento en seco

Energy Technology Data Exchange (ETDEWEB)

Munoz, A.; Montes, D.; Ruiz-Hervias, J.; Munoz-Reja, C.

2014-07-01

In order to complete previous studies of creep on PWR sheath material, developed a joint experimental program by CSN, ENRESA and ENUSA about BWR (Zircaloy-2) sheath material. This program consisted in creep tests and then on the material under creep, compression testing diametral obtaining the permissible displacement of the sheath to break. (Author)

Kritik Sosial terhadap Sistem Pendidikan Formal di Indonesia: Kajian Sosiologis Atas Novel Catatan Seorang Novelis Karya Maia Rosyida

OpenAIRE

PURARIYANI, ELOK DEWI

2013-01-01

Tujuan penelitian ini adalah mengungkap kaitan antarunsur struktur danmengungkapkan mendeskripsikan unsur-unsur struktur novel CSN dan mengungkapkanbagaimana penyimpangan-penyimpangan yang terjadi dalam sistem dan penyelenggaraanpendidikan di Indonesia. Untuk mengetahui penyimpangan-penyimpangan dalam sistempendidikan dalam novel Catatan Seorang Novelis makan penulis menggunakan teorisosiologi sastra. Penyajian hasil analisis data menggunakan metode deskriptif analisis. Metode inidigunakan un...

Rapid Large Earthquake and Run-up Characterization in Quasi Real Time

Science.gov (United States)

Bravo, F. J.; Riquelme, S.; Koch, P.; Cararo, S.

2017-12-01

Several test in quasi real time have been conducted by the rapid response group at CSN (National Seismological Center) to characterize earthquakes in Real Time. These methods are known for its robustness and realibility to create Finite Fault Models. The W-phase FFM Inversion, The Wavelet Domain FFM and The Body Wave and FFM have been implemented in real time at CSN, all these algorithms are running automatically and triggered by the W-phase Point Source Inversion. Dimensions (Large and Width ) are predefined by adopting scaling laws for earthquakes in subduction zones. We tested the last four major earthquakes occurred in Chile using this scheme: The 2010 Mw 8.8 Maule Earthquake, The 2014 Mw 8.2 Iquique Earthquake, The 2015 Mw 8.3 Illapel Earthquake and The 7.6 Melinka Earthquake. We obtain many solutions as time elapses, for each one of those we calculate the run-up using an analytical formula. Our results are in agreements with some FFM already accepted by the sicentific comunnity aswell as run-up observations in the field.

Neutron dosimetry inside the containment building of Spanish nuclear power plants with PADC based dosemeters

Energy Technology Data Exchange (ETDEWEB)

Garcia-Fuste, M.J. [Grup de Fisica de les Radiacions. Departament de Fisica. Edifici C. Universitat Autonoma de Barcelona, E-08193 Bellaterra (Spain); Domingo, C., E-mail: carles.domingo@uab.ca [Grup de Fisica de les Radiacions. Departament de Fisica. Edifici C. Universitat Autonoma de Barcelona, E-08193 Bellaterra (Spain); Amgarou, K.; Bouassoule, T.; Castelo, J. [Grup de Fisica de les Radiacions. Departament de Fisica. Edifici C. Universitat Autonoma de Barcelona, E-08193 Bellaterra (Spain)

2009-10-15

The Spanish Nuclear Safety Council (Consejo de Seguridad Nuclear, CSN) recommends performing neutron individual dose assignments at workplaces based on ambient dose equivalent measurements using area monitors and by estimating the amount of time that workers spend in the different monitored environments. In addition, some Spanish nuclear power plants estimate the neutron dose equivalent using albedo thermoluminescence dosemeters (TLD). In the period 2004-2006, our group, together with other research centers, participated in a project, funded by the CSN, with the support of the Spanish Nuclear Power Plants Association (UNESA), to investigate in situ which could be the best practical procedure for individual neutron dose monitoring in nuclear power plants. As part of this survey, several units of the UAB PADC based neutron dosemeter were exposed, on a methacrylate phantom simulating a human body, at four different places inside the containment building of the Asco I nuclear power plant. The influence of different types of calibration neutron fields is analysed and the dose equivalent for each point is estimated.

A Novel Wireless Power Transfer-Based Weighed Clustering Cooperative Spectrum Sensing Method for Cognitive Sensor Networks.

Science.gov (United States)

Liu, Xin

2015-10-30

In a cognitive sensor network (CSN), the wastage of sensing time and energy is a challenge to cooperative spectrum sensing, when the number of cooperative cognitive nodes (CNs) becomes very large. In this paper, a novel wireless power transfer (WPT)-based weighed clustering cooperative spectrum sensing model is proposed, which divides all the CNs into several clusters, and then selects the most favorable CNs as the cluster heads and allows the common CNs to transfer the received radio frequency (RF) energy of the primary node (PN) to the cluster heads, in order to supply the electrical energy needed for sensing and cooperation. A joint resource optimization is formulated to maximize the spectrum access probability of the CSN, through jointly allocating sensing time and clustering number. According to the resource optimization results, a clustering algorithm is proposed. The simulation results have shown that compared to the traditional model, the cluster heads of the proposed model can achieve more transmission power and there exists optimal sensing time and clustering number to maximize the spectrum access probability.

A Novel Wireless Power Transfer-Based Weighed Clustering Cooperative Spectrum Sensing Method for Cognitive Sensor Networks

Directory of Open Access Journals (Sweden)

Xin Liu

2015-10-01

Full Text Available In a cognitive sensor network (CSN, the wastage of sensing time and energy is a challenge to cooperative spectrum sensing, when the number of cooperative cognitive nodes (CNs becomes very large. In this paper, a novel wireless power transfer (WPT-based weighed clustering cooperative spectrum sensing model is proposed, which divides all the CNs into several clusters, and then selects the most favorable CNs as the cluster heads and allows the common CNs to transfer the received radio frequency (RF energy of the primary node (PN to the cluster heads, in order to supply the electrical energy needed for sensing and cooperation. A joint resource optimization is formulated to maximize the spectrum access probability of the CSN, through jointly allocating sensing time and clustering number. According to the resource optimization results, a clustering algorithm is proposed. The simulation results have shown that compared to the traditional model, the cluster heads of the proposed model can achieve more transmission power and there exists optimal sensing time and clustering number to maximize the spectrum access probability.

BEHAVIOR OF CÓRDIA AFRICANA (Cordia africana Lam. CULTIVATED IN SOIL CONTAMINATED BY HEAVY METALS AND TREATED WITH AMENDMENT MATERIALS

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Ana Carolina Callegario Pereira

2013-08-01

Full Text Available http://dx.doi.org/10.5902/1980509810544This study aimed to evaluate the remediation of two soils contaminated with heavy metals from soil excavations, located near the port of Itaguaí, through the techniques of chemical immobilization and phytostabilization using the species Cordia africana. The data were collected in the ore courtyard from ‘Companhia Siderúgica Nacional’ (CSN, in the port of Itaguaí, Rio de Janeiro state. In order to reduce the solubility of heavy metals present in these substrates, two industrial waste products produced by CSN were used as ameliorating products, the steelmaking slag and the mill scale, in different concentrations. The plant species was considered with potential to be used in programs of phytostabilization, due to its heavy metal tolerance studied and to high accumulation of such elements in roots and stem. In the substrate of low combination, the lowest accumulation of Zinc and Cadmium in stems and leaves occurred with the use of 4% of soothing. In the substrate of high accumaltion it was 6%.

Optimización del tratamiento de aguas residuales de cultivos de flores usando humedales construidos de flujo subsuperficial horizontal

Directory of Open Access Journals (Sweden)

Mónica L. Jaramillo-Gallego

2016-02-01

Full Text Available Resumen Objetivo: optimizar un sistema de tratamiento de aguas residuales de cultivos de flores, con el fin de mejorar la eficiencia en la remoción de los contaminantes, usando humedales construidos de flujo subsuperficial-horizontal. Metodología: se realizó un estudio de tipo exploratorio experimental en dos etapas, en la primera se efectuó el acondicionamiento fisicoquímico y biológico del sistema de tratamiento, en la segunda, se llevó a cabo el seguimiento de la remoción de los contaminantes durante nueve meses, para lo cual se monitoreó la demanda química de oxígeno, demanda biológica de oxígeno, sólidos totales, sólidos suspendidos totales, pH y oxígeno disuelto. Resultados: Se logró mejorar la eficiencia del sistema de tratamiento en 7,1% para la Demanda biológica de oxígeno, 4,1% Demanda química de oxígeno, 56,9% sólidos totales y 117,2% solidos suspendidos totales. Conclusión: La concentración de DQO disminuyó con el tratamiento primario (Precipitación y oxidación química y favoreció la eficiencia del sistema de tratamiento secundario, dado que las aguas a tratar tenían valores muy altos de DQO que pueden saturar los humedales con contaminantes persistentes. Se podrían obtener mayores eficiencias, si se logra mejorar el sistema de tratamiento primario. Abstract Objective: to optimize the wastewater treatment system of flower crops in order to improve pollutant removal efficiency, using a horizontal subsurface flow constructed wetland. Methodology: An exploratory experimental study was conducted in two stages; in the first stage the treatment system was conditioned physically, chemically and biologically. In the second stage pollutant removal was monitored for nine months. To achieve this, chemical oxygen demand, biological oxygen demand, total solids, total suspended solids, pH and dissolved oxygen were monitored. Results: It was possible to improve the efficiency of the treatment system in 7.1% for

Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat

Directory of Open Access Journals (Sweden)

Jianan Geng

2018-01-01

Full Text Available Diabetic nephropathy (DN is a major cause of end-stage renal disease throughout the world; until now there is no specific drug available. In this work, we use herba artemisiae capillaris extract (HACE to alleviate renal fibrosis characterized by the excessive accumulation of extracellular matrix (ECM in rats, aiming to investigate the protective effect of the HACE on DN. We found that the intragastric treatment of high-dose HACE could reverse the effect of streptozotocin not only to decrease the level of blood glucose and blood lipid in different degree but also further to improve renal functions. It is worth mentioning that the effect of HACE treatment was comparable to the positive drug benazepril. Moreover, we found that HACE treatment could on one hand inhibit oxidative stress in DN rats through regulating enzymatic activity for scavenging reactive oxygen species and on the other hand increase the ECM degradation through regulating the activity of metalloproteinase-2 (MMP-2 and the expression of tissue transglutaminase (tTG, which explained why HACE treatment inhibited ECM accumulation. On the basis of above experimental results, we conclude that HACE prevents DN development in a streptozotocin-induced DN rat model, and HACE is a promising candidate to cure DN in clinic.

Predicción de la estructura secundaria de proteínas usando Máquinas de soporte Vectorial

Directory of Open Access Journals (Sweden)

Darío José Delgado

2012-01-01

Full Text Available Título en ingles: Protein secondary structure prediction    using  support vector machines Abstract : Among the computational methods used for predicting secondary structure proteins highlights the use of support vector machines. This research shows the predicted secondary structure of protein from its primary amino acid sequence using Support Vector Machines. As inputs, in the proposed methodology, features are used from different structural motifs or text strings associated with the primary structure which represents the secondary structure, such as R-group and the probability that the amino acid at position adopts a central particular secondary structure. For feature extraction method is used coding of sequences in which each symbol in the primary structure is associated with each symbol in the secondary structure. The use of this encoding method reduces the dimensionality of the data of thousands of characteristics only 220 of these. The results obtained are comparable to those reported in the literature, taking about 70% accuracy. Furthermore, it is possible to reduce computational cost in the construction of classifiers because this work models the problem of multi classification as a group of binary classifiers. Key words: coding methodology; support vector machines; prediction of protein secondary structure. Resumen: Entre los métodos computacionales utilizados para la predicción de la estructura secundaria de proteínas, se destaca el uso de máquinas de soporte vectorial. Este trabajo de investigación presenta la predicción de la estructura secundaria de proteínas desde su secuencia primaria de aminoácidos usando Máquinas de Soporte Vectorial. Como entradas, en la metodología propuesta, se utilizan características de los diferentes motivos estructurales o cadenas de texto asociadas a la estructura primaria que representa la estructura secundaria, tales como el R-grupo y la probabilidad de que el aminoácido en la posici

Preliminary results of a high-resolution refractometer using the Hartmann-Shack wave-front sensor: part I Resultados preliminares com refratrômetro de alta resolução, usando sensor de frente de onda de Hartmann-Shack: parte I

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Luis Alberto Carvalho

2003-06-01

Full Text Available In this project we are developing an instrument for measuring the wave-front aberrations of the human eye using the Hartmann-Shack sensor. A laser source is directed towards the eye and its diffuse reflection at the retina generates an approximately spherical wave-front inside the eye. This wave-front travels through the different components of the eye (vitreous humor, lens, aqueous humor, and cornea and then leaves the eye carrying information about the aberrations caused by these components. Outside the eye there is an optical system composed of an array of microlenses and a CCD camera. The wave-front hits the microlens array and forms a pattern of spots at the CCD plane. Image processing algorithms detect the center of mass of each spot and this information is used to calculate the exact wave-front surface using least squares approximation by Zernike polynomials. We describe here the details of the first phase of this project, i. e., the construction of the first generation of prototype instruments and preliminary results for an artificial eye calibrated with different ametropias, i. e., myopia, hyperopia and astigmatism.Neste projeto estamos desenvolvendo instrumento para medidas das aberrações de frente de onda do olho humano usando um sensor Hartmann-Shack. Uma fonte de luz laser é direcionada ao olho e sua reflexão difusa na retina gera frente de onda aproximadamente esférica dentro do olho. Esta frente de onda atravessa os diferentes componentes do olho (humor vítreo, lente, humor aquoso e córnea trazendo informações sobre as aberrações ópticas causadas por estes componentes. No meio externo ao olho existe sistema óptico formado por uma matriz de microlentes e uma câmera CCD. A frente de onda incide nesta matriz e forma um padrão aproximadamente matricial de "spots" no plano do CCD. Algoritmos de processamento de imagens são utilizados para detectar os centróides de cada "spot" e esta informação é utilizada para

A Scientific Calculator for Exact Real Number Computation Based on LRT, GMP and FC++

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J. A. Hernández

2012-03-01

Full Text Available Language for Redundant Test (LRT is a programming language for exact real number computation. Its lazy evaluation mechanism (also called call-by-need and its infinite list requirement, make the language appropriate to be implemented in a functional programming language such as Haskell. However, a direction translation of the operational semantics of LRT into Haskell as well as the algorithms to implement basic operations (addition subtraction, multiplication, division and trigonometric functions (sin, cosine, tangent, etc. makes the resulting scientific calculator time consuming and so inefficient. In this paper, we present an alternative implementation of the scientific calculator using FC++ and GMP. FC++ is a functional C++ library while GMP is a GNU multiple presicion library. We show that a direct translation of LRT in FC++ results in a faster scientific calculator than the one presented in Haskell.El lenguaje de verificación redundante (LRT, por sus siglas en inglés es un lenguaje de programación para el cómputo con números reales exactos. Su método de evaluación lazy (o mejor conocido como llamada por necesidad y el manejo de listas infinitas requerido, hace que el lenguaje sea apropiado para su implementación en un lenguaje funcional como Haskell. Sin embargo, la implementación directa de la semántica operacional de LRT en Haskell así como los algoritmos para funciones básicas (suma, resta, multiplicación y división y funciones trigonométricas (seno, coseno, tangente, etc hace que la calculadora científica resultante sea ineficiente. En este artículo, presentamos una implementación alternativa de la calculadora científica usando FC++ y GMP. FC++ es una librería que utiliza el paradigma Funcional en C++ mientras que GMP es una librería GNU de múltiple precisión. En el artículo mostramos que la implementación directa de LRT en FC++ resulta en una librería más eficiente que la implementada en Haskell.

Análisis de consistencia de caminos bidireccionales usando mediciones continuas de velocidad de operación obtenidas con GPS Two-lane rural highways consistency analysis using continuous operating speed measurements obtained with GPS

Directory of Open Access Journals (Sweden)

Tomás Echaveguren

2012-08-01

Full Text Available El análisis de consistencia permite evaluar la seguridad en caminos en base a la velocidad. Existen diversos modelos velocidad - geometría para elementos aislados de una carretera, que se utilizan para evaluar la consistencia de elementos aislados del trazado de una carretera. Por ejemplo curvas horizontales simples o en curvas de inflexión en "S".Los modelos de análisis de consistencia agregados, permiten evaluar segmentos largos de trazado, por lo que necesitan perfiles de velocidad continuos. En este caso, los modelos y mediciones puntuales de velocidad no son adecuados. Actualmente, la tecnología de posicionamiento satelital es una manera eficiente de construir perfiles de velocidad en largas distancias del trazado, siendo particularment útil para aplicar el método de Polus. Este trabajo estudia el modelo de análisis de consistencia de Polus usando perfiles continuos de velocidad. Primero se discute dicho modelo, para luego presentar la obtención y tratamiento de datos de velocidad usando modelos y mediciones directas. El método se aplicó a 5 casos de estudio en los cual se midió en terreno la velocidad y geometría con un GPS partir del cual se obtuvieron perfiles directos y teóricos de velocidad .Los datos fueron procesados con el filtro de Kalman y suavizados con el método LOESS, para luego evaluar la consistencia de cada ruta. Se concluyó que el método de Polus y los perfiles contínuos de velocidad medidos permiten obtener una calificación de segmentos largos del trazado, pero se debe segmentar adecuadamente cada trazado para evitar sub/sobre estimaciones de consistencia.Consistency assessment permits to study road safety regarded to speed. There exist several speed-geometry models that assessed isolated components of roads, which are used for consistency assessment of single elements of roads. For instance, single horizontal curves or reverse curves. Aggregated consistency assessment models, permit to assess long

Analysis of the results of environmental monitoring in Spain after the Chernobyl and Fukushima accidents

International Nuclear Information System (INIS)

Luque Heredia, S.; Salas Collantes, R.; Rey del castillo, C.; Marugar tovar, I.; Sterling carmona, A.; Ramos Salvador, L.; Lorente Lorente, P.

2013-01-01

As a result of accidents at Chernobyl and Fukushima nuclear power plants, CSN launched special surveillance devices to monitor radioactive contamination through the values provided by the various networks and environmental monitoring programs. The aim of this study is to compare and analyze the results corresponding to the exposure pathways and matrices in which contamination is detected. (Author)

Determining the frequencies of B1, B2, B3 and E alleles of the ...

African Journals Online (AJOL)

Ada

2016-06-04

Jun 4, 2016 ... bp of intronic regions with a total similarity with the corresponding ... (1.93%) than in milks of the 'strong' group (2.05%) in Norwegian dairy .... employed was: ..... protein, fat, TS, SNF, casein and lactose percentage were found by .... CSN1S1 locus by PCR-RFLP and AS-PCR in a Neapolitan goat population.

Energy in the 21st Century

International Nuclear Information System (INIS)

Rubio, J. A.

2005-01-01

Having reached the 25th Anniversary of the Nuclear Safety Council (CSN) the general director of the Environmental and Technological energy Research Centre (CIEMAT) has written an article narrating the evolution of both institutions and the relationship between them, as well as setting out the current energy situation and how it will evolve within the next few years. (Author)

Browse Title Index

African Journals Online (AJOL)

Items 1 - 50 of 52 ... Issue, Title. Vol 15 (2000), Ammi analysis of maize yield trials in South-Western Nigeria, Abstract. SR Ajibade, BA Ogunbodede. Vol 20 (2006), Association of yield with some agronomic characters in potatoes in a cool mid-altitude location, Abstract. CO Amadi, EE Ene Obong. Vol 20 (2006), Casein (CSN3) ...

Nuclear Mis-Communication: Who's to Blame?

International Nuclear Information System (INIS)

MaLachlan, A.

1997-01-01

The text reproduces entirely the conference that was pronounced by Ann MacLachlan at the CSN in October 1996 about the problems of the public communication in the particular case of nuclear energy. The author meditates upon the causes of the lack of understanding between the involved sides and the suspected formulae in order to overcome the difficulties. (Author)

Analysis of the evolution of the collective dose in nuclear power plants in Spain; Analisis de la evolucion de la dosis colectiva en las centrales nucleares de Espana

Energy Technology Data Exchange (ETDEWEB)

Ponjuan Reyes, G.; Ruibia Rodiz, M. A. de la; Rosales Calvo, M.; Labarta Mancho, T.; Calavia Gimenez, I.

2011-07-01

This article presents an analysis of the evolution of occupational collective dose of the Spanish nuclear power plants during the period 2000 - 2008 within the international context, by the Nuclear Safety Council (CSN) in order to have information contrasted to assessing the extent of application of the ALARA criteria in the Spanish plants and identify areas of priority attention.

Second Meeting for Evaluation of the Nuclear Safety Convention

International Nuclear Information System (INIS)

2002-01-01

This report presents the results of the Second Meeting for Evaluation of the Nuclear Safety Convention. the CSN. as the only competent Government organism on nuclear safety, represented Spain in the preparation of the national report and at the Review Meeting, acquiring a set of obligations for the next three years, until the holding of third meeting. (Author)

From Molecular Biology to Biomedicine

International Nuclear Information System (INIS)

Salas, M.

2009-01-01

From Molecular Biology to Biomedicine. The well known molecular biologist Margarita Salas offered an informative conference at the CSN on progress in these areas since the discovery, more than half a century ago, of the structure of the molecule carrying genetic information, DNA, work that is having an enormous impact in areas such as biomedicine and foodstuff production. (Author)

Analysis of two single-nucleotide polymorphisms (SNPs) located in ...

African Journals Online (AJOL)

Martina Franca donkey was derived from the Catalan donkey brought to Apulia at the time of the Spanish rule. This donkey is tall and well built and has good temperament. Both considered loci were found to be monomorphic in the considered population. At CSN3/PstI locus, all the animals were genotyped as AA since no ...

Forecasting of time series with trend and seasonal cycle using the airline model and artificial neural networks Pronóstico de series de tiempo con tendencia y ciclo estacional usando el modelo airline y redes neuronales artificiales

Directory of Open Access Journals (Sweden)

J D Velásquez

2012-06-01

Full Text Available Many time series with trend and seasonal pattern are successfully modeled and forecasted by the airline model of Box and Jenkins; however, this model neglects the presence of nonlinearity on data. In this paper, we propose a new nonlinear version of the airline model; for this, we replace the moving average linear component by a multilayer perceptron neural network. The proposedmodel is used for forecasting two benchmark time series; we found that theproposed model is able to forecast the time series with more accuracy that other traditional approaches.Muchas series de tiempo con tendencia y ciclos estacionales son exitosamente modeladas y pronosticadas usando el modelo airline de Box y Jenkins; sin embargo, la presencia de no linealidades en los datos son despreciadas por este modelo. En este artículo, se propone una nueva versión no lineal del modelo airline; para esto, se reemplaza la componente lineal de promedios móviles por un perceptrón multicapa. El modelo propuesto es usado para pronosticar dos series de tiempo benchmark; se encontró que el modelo propuesto es capaz de pronosticar las series de tiempo con mayor precisión que otras aproximaciones tradicionales.

Analysis of the indices of thermal comfort for the conditions of the Mexican Republic; Analisis de los indices de confort termico para las condiciones de la republica mexicana

Energy Technology Data Exchange (ETDEWEB)

Fuentes Freixanet, Victor; Rodriguez Viqueira, Manuel [Universidad Autonoma Metropolitana - Unidad Azcapotzalco (Mexico)

2009-07-15

The objective of this article is to analyze different indices of thermal comfort for the Mexican Republic. Among them the Fanger (PMV and PPD) physiological methods of comfort and the new effective temperature index are included. The standard effective temperature (SET), as well as the adaptive methods of Humphreys and Nicol, Auliciems, De Dear and Brager. A comparative analysis is done of the different indices through thematic maps determined by interpolation, using a climatic data base of 700 cities obtained from the observatories and stations of the National Meteorological Service. This article pretends to establish general criteria of the thermal comfort to later define design strategies for each one of the climatic regions of the Mexican Republic. [Spanish] El objetivo de este articulo es analizar distintos indices de confort termico para la Republica Mexicana. Entre ellos se incluyen los metodos fisiologicos de confort de Fanger (PMV y PPD), el indice de nueva temperatura efectiva. La temperatura efectiva estandar (SET), asi como los metodos adaptativos de Humphreys y Nicol, Auliciems, De Dear y Brager. Se hace un analisis comparativo de los distintos indices a traves de mapas tematicos determinados por interpolacion, usando una base de datos climaticos de 700 ciudades obtenidos de los observatorios y estaciones del Servicio Meteorologico Nacional. Este articulo presenta establecer criterios generales del confort termico para posteriormente definir estrategias de diseno para cada una de las regiones climaticas de la Republica Mexicana.

Explorando nuevos recursos virtuales con alumnos de Informática: aplicaciones educativas a las clases de Inglés

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Martin, C. Adriana Nelly

2012-12-01

Full Text Available El hecho innegable que los recursos de la Web Social han impactado positivamente en la enseñanza de lenguas extranjeras, nos hace abrirnos a la perspectiva que supone la transferencia de dichas tecnologías al campo educativo. A tal efecto, sostenemos que los actuales quehaceres y prácticas educativas resultan fértiles para ser potenciados con la adopción de aplicaciones tecnológicas innovadoras, que signifiquen una ganancia cognitiva tanto para los que aprenden como para los que enseñan. Este trabajo presenta una experiencia educativa en la que participaron alumnos que cursaban la asignatura Inglés II, incluida en los planes de estudio de las Licenciaturas en Ciencias de la Computación y en Sistemas de Información, pertenecientes a la Facultad de Ciencias Exactas, Físicas y Naturales de la UNSJ (Argentina. La propuesta tomó como referencia el Modelo COMPETICE y tenía como objetivo que los alumnos aplicaran competencias tecnológicas, procedimentales, actitudinales y de gestión de información, usando diversos recursos digitales orientados a promover no sólo aprendizajes individuales autónomos sino también sociocolaborativos. Se diseñaron tareas extra-áulicas para que los estudiantes vivenciaran el uso de diccionarios, glosarios, traductores, gramáticas en línea y foro, y los aplicaran para adquirir conocimientos de su especialidad, investigar y autogestionar contenidos curriculares de la asignatura

EFECTO DE RECUBRIMIENTO DE ALMIDÓN DE YUCA Y CERA DE ABEJAS SOBRE EL CHONTADURO

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ZULMA LIZETH TOSNE

Full Text Available El chontaduro tiene alto valor nutritivo y es uno de los frutos más completos como alimento, sin embargo, es altamente perecedero lo que lo hace susceptible a sufrir daños que afectansu calidad y aceptación. Por lo anterior, se evaluó el efecto de un recubrimiento a base de almidón de yuca (variedad SM 707-17 modificado enzimáticamente y cera de abejas sobre lapérdida de peso, la firmeza, los grados Brix, la acidez titulable y la tasa respiratoriade frutos variedad roja en etapa pos cosecha, almacenados bajo condiciones ambientales (18oC y 77,7% de humedad relativa. Se usó un diseño completamente al azar con cuatro tratamientos: T1 muestra testigo, T2 con 0,5% de cera de abejas, T3 con 1,5% de cera de abejas, T4 con 2,5% de cera de abejas, todos adicionados de almidón de yuca modificado (al 4%, glicerina y carboximetilcelulosa (CMC. Se realizaron 3 réplicas y los resultados se sometieron a un análisis de varianza (α=0,05 usando el software SPSS 19, con un nivel de significancia (p<0,05 en las variables de respuesta, identificando T3 como el tratamiento con mayor incidencia, manteniendo las condiciones de calidad del chontaduro por un periodo adicional de 4 días.

Penología e indigenismo en la antigua Guinea española

Directory of Open Access Journals (Sweden)

Pedro María Belmonte Medina

1998-01-01

Full Text Available Este artículo de investigacióm pretende ser un estudio histórico-juridico del derecho penal que los españoles aplicaron a los indígenas de la Guinea española. Partiendo de la base de que el derectio penal guíneano-español se basaba, principalmente, en el reconocimiento de normas indígenas de tipo consuetudinario (derecho indígena, a través de sentencias judiciales y por adaptaciones del derecho metropolitano, usando como vehículo de expresión, así mismo, la jurisprudencia aplicada por los tribunales de raza españoles, se hace un amplio estudio de las penas que los españoles aplicaron a los indígenas, dividiendo la obra en dos parles: derecho para indígenas y derecho indígena.This work tries to be a historic-juridical study about penal law that spanish people applied to natives fron the spanish guinea. From the point of view that this law was, mainly, based on the knowledge of the natives rules about habits and native law, through sentences and the adaptation of the metropolitan law, using as mass media, the jurisprudence applied by the spanish courts, a huge study, is made about the punishments spanish people applied to natives. The study is divided in two parts: native law and law for natives.

On the approximation of the inverse dynamics of a robotic manipulator by a neural network trained with a stochastic learning algorithm

Directory of Open Access Journals (Sweden)

Enrique Carlos Segura

2013-07-01

Full Text Available Se utiliza el algoritmo SAGA para aproximar la dinámica inversa de un manipulador robótico con dos juntas rotacionales. SAGA (Simulated Annealing + Gradiente + Adaptación es una estrategia estocástica para la construcción aditiva de una red neuronal artificial de tipo perceptrón de dos capas, basada en tres elementos esenciales: a actualización de los pesos de la red por medio de información del gradiente de la función de costo; b aceptación o rechazo del cambio propuesto por una técnica de recocido simulado (simulated annealing clásica; y c crecimiento progresivo de la red neuronal, en la medida en que su estructura resulta insuficiente, usando una estrategia conservadora para agregar unidades a la capa oculta. Se realizan experimentos y se analiza la eficiencia en términos de la relación entre error relativo medio -en los conjuntos de entrenamiento y de testeo-, tamaño de la red y tiempos de cómputo. Se hace énfasis en la habilidad de la técnica propuesta para obtener buenas aproximaciones, minimizando la complejidad de la arquitectura de la red y, por lo tanto, la memoria computacional requerida. Además, se discute la evolución del proceso de minimización a medida que la superficie de costo se modifica.

An experience in the management of personal dosimetry and Information and Communication Technologies; Una experiencia en la gestión de la dosimetría personal y las Tecnologías de la Información y las Comunicaciones

Energy Technology Data Exchange (ETDEWEB)

Galán Montenegro, P.; Sánchez Hidalgo, M.; Bodineau, C.; Oliveros Fernández, B.

2015-07-01

One of the most frequently issues raised within the management of hospital personnel dosimetry service is the high incidence of the rate evidencing the lack of dosimeter badges replacement in personnel dosimetry on monthly basis. In this respect and following the enforcement of the dispositions ordered by the CSN (Spanish Nuclear Safety Council as Regulatory Agency) concerning the assignment of “administrative dose”, such rate turns currently into a high number of these doses assigned, thus leading to an inefficient monitoring of the personnel dosimetry. In order to achieve a more suitable dosimetry monitoring it is required a more direct and tailored management of personnel dosimetry in every occupationally exposed workers as well as providing with personal and fluent information. The total number of occupationally exposed workers and the diversity and geographical dispersion of the centers under dosimetry monitoring make impossible a customized management without involving substantial resources. With the aim of achieving a more tailored management in an scenario as the one described above as well as reducing the lack of replacement of dosimeter badges in personnel dosimetry on monthly basis and the administrative doses assigned, some measures were implemented in 2009 by applying Communications and Information Technology platforms and further employees management giving as a result a 75% reduction in the rate of non replacement of dosimeter badges in personnel dosimetry. [Spanish] Una de las cuestiones habitualmente planteada en la gestión de la dosimetría personal hospitalaria es la alta incidencia en la tasa de no recambio mensual de los dosímetros personales y desde la aplicación de la instrucción del Consejo de Seguridad Nuclear (CSN) sobre la asignación de la dosis administrativa, esto supone en la actualidad un alto número de las mencionadas asignaciones; lo que conlleva un deficiente control de la dosimetría personal. Para un mejor control dosim

Preventing High Altitude Cerebral Edema in Rats with Repurposed Anti-Angiogenesis Pharmacotherapy.

Science.gov (United States)

Tarshis, Samantha; Maltzahn, Joanne; Loomis, Zoe; Irwin, David C

2016-12-01

High altitude cerebral edema (HACE) is a fulminant, deadly, and yet still unpredictable brain disease. A new prophylactic treatment for HACE and its predecessor, acute mountain sickness (AMS), needs to be developed without the contraindications or adverse effect profiles of acetazolamide and dexamethasone. Since neovascularization signals are likely key contributors to HACE/AMS, our approach was to examine already existing anti-angiogenic drugs to inhibit potential initiating HACE pathway(s). This approach can also reveal crucial early steps in the frequently debated mechanism of HACE/AMS pathogenesis. We exposed four rat cohorts to hypobaric hypoxia and one to sea level (hyperbaric) conditions. The cohorts were treated with saline controls, an anti-angiogenesis drug (motesanib), a pro-angiogenesis drug (deferoxamine), or an intraperitoneal version of the established AMS prophylaxis drug, acetazolamide (benzolamide). Brain tissue was analyzed for cerebrovascular leak using the Evans Blue Dye (EVBD) protocol. We observed significantly increased EVBD in the altitude control and pro-angiogenesis (deferoxamine) cohorts, and significantly decreased EVBD in the anti-angiogenesis (motesanib), established treatment (benzolamide), and sea-level cohorts. Anti-angiogenesis-treated cohorts demonstrated less cerebrovascular extravasation than the altitude control and pro-angiogenesis treated rats, suggesting promise as an alternative prophylactic HACE/AMS treatment. The leak exacerbation with pro-angiogenesis treatment and improvement with anti-angiogenesis treatment support the hypothesis of early neovascularization signals provoking HACE. We demonstrate statistically significant evidence to guide further investigation for VEGF- and HIF-inhibitors as HACE/AMS prophylaxis, and as elucidators of still unknown HACE pathogenesis.Tarshis S, Maltzahn J, Loomis Z, Irwin DC. Preventing high altitude cerebral edema in rats with repurposed anti-angiogenesis pharmacotherapy. Aerosp Med

Analysis of multiple spurions and associated circuits in Cofrentes

International Nuclear Information System (INIS)

Molina, J. J.; Celaya, M. A.

2015-01-01

The article describes the process followed by the Cofrentes Nuclear Power Plant (CNC) to conduct the analysis of multiple spurious in compliance with regulatory standards IS-30 rev 1 and CSN Safety Guide 1.19 based on the recommendations of the NEI-00-01 Guidance for Post-fire Safe Shutdown Circuit and NUREG/CR-6850. Fire PRA Methodology for Nuclear Power Facilities. (Author)

Analysis of multiple spurions and associated circuits in Cofrentes; Analisis de espurios multiples y circuitos asociados en C.N. Cofrentes

Energy Technology Data Exchange (ETDEWEB)

Molina, J. J.; Celaya, M. A.

2015-07-01

The article describes the process followed by the Cofrentes Nuclear Power Plant (CNC) to conduct the analysis of multiple spurious in compliance with regulatory standards IS-30 rev 1 and CSN Safety Guide 1.19 based on the recommendations of the NEI-00-01 Guidance for Post-fire Safe Shutdown Circuit and NUREG/CR-6850. Fire PRA Methodology for Nuclear Power Facilities. (Author)

Analysis of the evolution of the collective dose in nuclear power plants in Spain

International Nuclear Information System (INIS)

Ponjuan Reyes, G.; Ruibia Rodiz, M. A. de la; Rosales Calvo, M.; Labarta Mancho, T.; Calavia Gimenez, I.

2011-01-01

This article presents an analysis of the evolution of occupational collective dose of the Spanish nuclear power planLs during the period 2000 - 2008 within the international context, by the Nuclear SafeLy Council (CSN) in order to have information contrasted to assessing the extent of applicaLion of the ALARA criLeria in the Spanish plants and identify areas of priority attention.

Steam generators regulatory practices and issues in Spain

International Nuclear Information System (INIS)

Mendoza, C.; Castelao, C.; Ruiz-Colino, J.; Figueras, J.M.

1997-01-01

This paper presents the actual status of Spanish Steam Generator tubes, actions developed by PWR plant owners and submitted to CSN, and regulatory activities related to tube degradation mechanisms analysis; NDT tube inspection techniques; tube, tubesheet and TSPs integrity studies; tube plugging/repair criteria; preventive and corrective measures including whole SGs replacement; tube leak measurement methods and other operational aspects

Reload shutdown for Nuclear Power Stations in spain in 2003

International Nuclear Information System (INIS)

2004-01-01

Regarding time reductions in fuel reloading at Spanish nuclear power stations, the Spanish Nuclear Security Council (CSN), at the request of the Spanish Finance and Treasury Department of the Chamber of Deputies, delivered an instruction, by which power station's owners were urged to establish a detailed planning of reload operations. This article includes the results of this instruction. (Author) 6 refs

PSA results and trends for Spain's NPPs

International Nuclear Information System (INIS)

Carretero, J.A.

1993-01-01

The Spain regulatory authority CSN demanded performance of PSA for all Spain nuclear power plants. The specific data analysis carried out as a part of the PSA has contributed to the realistic view on the results which could be achieved by the PSA. The main characteristics of the PSA in Spain and PSA trends in the development are presented in the paper

Radiological risk perception in Spain

International Nuclear Information System (INIS)

Martinez-Arias, R.; Prades, A.; Meza, R.; Sola, R.

1997-01-01

How does society perceive radiation risks?. Is there any logic underlying those perceptions?.The article describes the results of a cross-cultural survey on radiological risk perception applied to a representative sample of the Spanish population. This study has been carried out in the framework of a research project subsidized by the European Union and the CSN. (Author) 16 refs

Autoconceito dos professores: principais factores usando modelos de Análise de Dados Multivariada Teachers' self-concept: finding main factors and clusters by EDA models

Directory of Open Access Journals (Sweden)

Vitor Franco

2008-01-01

Full Text Available O autoconceito tem sido considerado uma dimensão muito importante da personalidade do professor, da sua prática e do seu desenvolvimento pessoal (MARKUS; WURF, 1987; SIMÕES, 2001. A investigação que apresentamos foi efectuada com 281 professores de Ciências da Natureza, do terceiro ciclo do Ensino Básico, em Portugal, usando o ICAC- Inventário Clínico do Auto Conceito (VAZ-SERRA, 1986. Na análise dos dados obtidos foram usados diferentes métodos de Análise Multivariada, apresentando-se os resultados da análise factorial de correspondências e nos modelos de classificação hierárquica baseados no coeficiente de afinidade. Os resultados obtidos: 1 confirmam a importância de dois grandes factores presentes no Autoconceito: aceitação social e auto-eficácia; 2 caracterizam estes principais factores no que se refere ao Autoconceito clínico dos professores; 3 mostram como esses factores são determinantes na forma como cada professor constroi o seu autoconceito.The self-concept has been considered as a very important dimension on teacher's personality, practice and development (MARKUS; WURF, 1987;SIMÕES, 2001. The present research concerns a sample of 281 teachers of Natural Science of the Third Cycle of Basic Education from Portugal that responded to the I.C.A.C. - Self-Concept Clinical Inventory (VAZ-SERRA, 1986. In the analysis of the questionnaires different multivariate data analysis methods have been used. This paper describes some results issued from correspondence analysis and hierarchical clustering models based on the affinity coefficient. The results obtained: 1 confirm the importance of two general main factors / types which are present in self-concept: social acceptance and self-efficiency; 2 characterise these main factors when teachers'clinical self-concept is concerned and 3 show how determinant these factors are for the building of self-concept that allow us to differentiate teachers.

Modelo matemático de transporte aplicado a una compañia dedicada a la manufactura y distribución de juguetes, usando programación lineal entera

Directory of Open Access Journals (Sweden)

Juan Andrés López Barreras

2008-07-01

Full Text Available Como resultado de esta Investigación, se presentará un modelo de transporte usando programación lineal. El proceso general de distribución se organiza en niveles que se suceden entre la empresa y sus respectivos clientes. En cada nivel se pueden ver claramente unidades de origen-destino, entre un origen y varios destinos, con transporte directo y con holguras en las fechas de entrega de los pedidos a transportar. La programación de la distribución se realiza en cada unidad, utilizando programación lineal entera, considerando en la formulación flotilla limitada e ilimitada de transportes. La programación global se obtiene como superposición de las programaciones de todas las unidades origen-destino. Para validar el modelo se han utilizado los datos proporcionados por una empresa del sector industrial Manufacturero (fábrica de juguetes que cumple las características requeridas. This article presents a mathematical model transport using linear programming. The global process of distribution is considered to be divided in successive levels between the company and yours clients. In every level units of origin - destination are distinguished, between an origin and several destinations, by direct transport and by roominess’s in the delivery dates of the orders to transporting. The programming of the distribution is realized in every unit, using linear entire programming, considering in the formulation limited and unlimited flotilla of transport. The global programming obtains as overlapping of the programming of all the units origin - destination. To validate the model there has been in use the information provided by a company of the industrial Manufacturing sector (factory of toys that fulfills the needed characteristics.

FUNGISTATIC PROPERTIES OF GRANULATED BLASTFURNACE SLAG AND RELATED SLAG-CONTAINING CEMENTS

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Julius Strigac

2016-03-01

Full Text Available The article deals with studying the antifungal effect of ground granulated blastfurnace slag (GGBS and the cements made from it. Antifungal effects were tested on the fungi using the procedure given in the Czech national standard CSN 72 4310: 1977 - Testing the mould proofness properties of building products and materials. A mixture of the fungi Aspergillus niger, Chaetomium globosum, Penicillium funiculosum, Paecilomyces variotii and Gliocladium virens was used for testing. The scale for evaluating mould proofness properties according to CSN 72 4310: 1977 is from 0 to 5 in degree of fungi growth, where a value of 0 means that no growth of fungi occurs and the building products and materials possess fungistatic properties. The study confirms the fungistatic propeties of GGBS with mould proofness property 0. The addition of GGBS to cements from 65 wt.% to 95 wt.% ensures the achieving of a fungistatic environment, which enables the production of fungistatic blastfurnace cements CEM III/A 32.5 N (with GGBS content of 65 wt.%, CEM III/B 32.5 N and CEM III/C 32.5 N with mould proofness property 0.

Analysis of results from intercomparison among Spanish laboratories involved of photon energy ''137 Cs for environmental dosimetry laboratories

International Nuclear Information System (INIS)

Gonzalez, A.M.; Brosed, A.; Salas, R.

2003-01-01

Any environmental thermoluminescent dosemeter (TLD) system must be periodically calibrated at a calibration laboratory. In this frame, the Consejo de Seguridad Nuclear (CSN) has performed an intercomparison among Spanish laboratories involved in environmental monitoring, by means of TLD, in order to verify the traceability of the whole dosimeter and reader to the national standard for the protection quantities of interest for a given photon energy (''137Cs). To achieve this goal the CSN asked the Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT) to carry out the reference irradiations in the energy above mentioned at the lonising Radiations Metrology Unit headquarters. Nine laboratories have participated. All the dosemeters were irradiated with the same air kerma rate. The radiological quantity used was the ambient dose equivalent, H (10), and the values of this quantity assigned to each laboratory were between 210 and 360 μSv. All the dosemeters of the participating laboratories met the two analysis criteria used. All of them demonstrated a satisfactory fulfilment of the requirements established by so called trumpet curves and of the requirements established by the ANSI 1311. (Author) 7 refs

Limitaciones constitucionales que afectan a la elección del Congreso de los Diputados : posible modificación del artículo 68 de la Constitución y reparto a dos niveles.

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Victoriano Ramírez González

2006-09-01

Full Text Available La Constitución de 1978, en los artículos 9 y 14, establece la igualdad de los individuos y de los grupos en que se integran, sin que pueda prevalecer discriminación alguna por razón de opinión u otra circunstancia personal. Sin embargo, en el artículo 68, establece limitaciones relativas al sistema electoral para la elección del Congreso de los Diputados que conducen a diferencias importantes del valor del voto de los ciudadanos dependiendo del partido al que se vote y la circunscripción a la que se está adscrito. Este trabajo muestra los principales agravios que produce la elección del Congreso cuando se comparan votos totales y escaños totales recibidos por los diferentes partidos políticos. En muchas ocasiones un partido con más votos que otro recibe menos escaños que ese otro. Siempre resultan perjudicados los partidos de ámbito estatal al compararlos con los partidos de ámbito autonómico que han obtenido similar número de votos. Por otra parte, se recoge el concepto de asignación de escaños a dos niveles (condicionando el reparto a segundo nivel a los resultados obtenidos en el reparto a primer nivel, como se hace para la elección del Bundestag en Alemania, y se resaltan las ventajas de ese sistema. A continuación se muestra un reparto a dos niveles para la elección del Congreso usando los datos electorales de 2004, sin necesidad de diseñar distritos uninominales, como en Alemania, sino usando exclusivamente como circunscripciones las provincias (además de las ciudades de Ceuta y Melilla. Con el reparto a dos niveles los principales agravios, que se han producido en las nueve elecciones generales celebradas entre 1977 y 2004, desaparecen y, al mismo tiempo, aumenta la proporcionalidad del sistema electoral sin dificultar la gobernabilidad. Finalmente, con objeto de que un reparto a dos niveles pueda recogerse, si se desea, en una modificación de la Ley Electoral de 1985 y esté garantizada la constitucionalidad de

Comparação das técnicas transarterial e de estimulação de múltiplos nervos para bloqueio do plexo braquial por via axilar usando lidocaína com epinefrina Comparación de las técnicas transarterial y de estimulación de múltiples nervios para bloqueo del plexo braquial por vía axilar usando lidocaína con epinefrina Comparison of transarterial and multiple nerve stimulation techniques for axillary block using lidocaine with epinephrine

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Luiz Eduardo Imbelloni

2005-02-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A técnica transarterial com grandes doses de anestésico local resulta em alta efetividade para o bloqueio axilar do plexo braquial. A técnica utilizando múltiplos estímulos exige mais tempo e maior experiência. Este estudo prospectivo compara a latência e o índice de sucesso do bloqueio do plexo braquial usando duas técnicas de localização: transarterial ou múltipla estimulação dos nervos. MÉTODO: A lidocaína com epinefrina, 800 mg, foi usada inicialmente para o bloqueio axilar. No grupo transarterial, 30 mL de lidocaína a 1,6% com epinefrina foram injetados profundamente e 20 mL superficialmente à artéria axilar. No grupo de múltipla estimulação, três nervos foram localizados eletricamente e bloqueados com volumes 20 mL, 20 mL e 10 mL da solução. O bloqueio foi considerado efetivo quando a analgesia estava presente em todos os nervos na área distal ao cotovelo. RESULTADOS: O tempo de latência (8,8 ± 2,3 min versus 10,2 ± 2,4 min; p-valor = 0,010 foi significativamente menor no grupo transarterial. Bloqueios sensitivos completos nos quatro nervos (mediano, ulnar, radial e musculocutâneo foram obtidos em 92,5% versus 83,3% no grupo de múltipla estimulação e acesso transarterial, respectivamente sem diferença significativa (p-valor = 0,68. O nervo musculocutâneo foi significativamente mais fácil de bloquear com o estimulador de nervo periférico (p = 0,034. CONCLUSÕES: A técnica de múltipla estimulação para o bloqueio axilar usando estimulador de nervos (3 injeções e a técnica transarterial (2 injeções produzem resultados semelhantes na qualidade do bloqueio. O nervo musculocutâneo é mais facilmente bloqueado com o uso do estimulador de nervo periférico. A técnica de múltipla estimulação necessitou menor suplementação do bloqueio e aumentou o tempo para o início da cirurgia.JUSTIFICATIVA Y OBJETIVOS: La técnica transarterial con grandes dosis de anestésico local

New guides and practices for incident analysis in the CSN

International Nuclear Information System (INIS)

Munuera, A.; Reig, J.

1990-01-01

Due to the reduced number of plants and the wide variety of designs, until now Trend and Pattern Analysis has not been performed in a systematic bases. However considering the importance of operating experience feedback and other application, several actions are being initiated in this field by the Regulatory Body in Spain. This paper describes the recent actions taken in this direction, a new Safety Guide related with Reportable Events has been developed and also a new Group of Specialists to deal exclusively with Operating Experiences is expected to be operative in the near future

Declassification, an actual operating materials management option in Cofrentes; La descalsificacion, una opcion operativa real de gestion de materiales en C. N. Cofrentes

Energy Technology Data Exchange (ETDEWEB)

Garcia-Bermejo, R.; Diego compadre, J. L. de; Lopez Alvarez, L.; Analya Lazaro, M.

2014-07-01

Methods and procedures developed for declassification feature a series of methodological options and innovative technology, including the systematic use of the spatial random variable named index of Residual activity, level specific factors for declassification determined empirically for each unit of characterization and contrasts of hypothesis not parametric which are used in the demonstration of compliance of the levels of declassification Decision rules authorized by the CSN. (Author)

Declassification, an actual operating materials management option in Cofrentes

International Nuclear Information System (INIS)

Garcia-Bermejo, R.; Diego compadre, J. L. de; Lopez Alvarez, L.; Analya Lazaro, M.

2014-01-01

Methods and procedures developed for declassification feature a series of methodological options and innovative technology, including the systematic use of the spatial random variable named index of Residual activity, level specific factors for declassification determined empirically for each unit of characterization and contrasts of hypothesis not parametric which are used in the demonstration of compliance of the levels of declassification Decision rules authorized by the CSN. (Author)

Correlação de longo alcance em sistemas binários de raios-x usando remoção de flutuações

Science.gov (United States)

Pereira, M. G.; Moret, M. A.; Zebende, G. F.; Nogueira, E., Jr.

2003-08-01

Neste trabalho é proposta uma metodologia de analise de series temporais de fontes astrofísicas, baseada no método proposto por Peng et al. (1994) e Liu et al. (1999), o qual consiste na idéia de que uma série temporal correlacionada pode ser mapeada por um processo de busca de auto-similaridades em diversas escalas de tempo n. Removendo as eventuais tendências e integrando o sinal observado, é obtida uma medida do desvio médio quadrático das flutuações do sinal integrado F(n)~na, onde a representa o fator de escala associado com a auto-similaridade da correlação de longo alcance do sinal. Baseado nos valores obtidos de a, é possível distinguir entre os casos de sinais não-correlacionados, tipo ruído branco (a = 0,5), sinal anti-persistentes (a 0,5). Usando esta metodologia, foram analisadas 129 curvas de luz de sistemas binários de raios-X, provenientes do banco de dados públicos de observações feitas pelo instrumento All Sky Monitor, a bordo do satélite Rossi X-Ray Timing Explorer (ASM-RXTE). Foram identificadas a presença de a'0,5 em mais de 90% dos sistemas estudados, implicando em dizer que as flutuações de intensidade observadas apresentam correlação de auto-similaridade, sem entretanto, indícios de apresentarem uma escala de tempo característica das flutuações de intensidade. Sistemas onde são observadas erupções (flares), apresentam sistematicamente a > 0,5, característica esta, possivelmente associada com persistência das flutuações de densidade de disco ou taxa de acréscimo de massa. Os sistemas com curvas de luz onde nao são observadas as erupções apresentam uma distribuição normal centrada em a~0,62+/-0,10. Referências ¾ Peng, C.-K., Buldyrev, S.V., Havlin, S., Simons, M., Stanley, H.E., e Goldberg, A.L., Phys. Rev. E, (49), 1685 (1994). ¾ Liu, Y., Gopikrishnan, P., Cizeau, P., Meyer, M., Peng,C.-K., e Stanley, H.E., Phys. Rev. E, (60), 1390 (1999).

Cierre de una fístula oroantral usando cemento óseo y un colgajo de mucosa yugal Closure of an oroantral fistula using bone cement and a jugal mucosa flap

Directory of Open Access Journals (Sweden)

Beatriz Ágreda Moreno

2012-03-01

Full Text Available Una fístula oroantral es una solución de continuidad patológica entre el seno maxilar y la cavidad oral, producida frecuentemente tras una extracción dentaria, en la mayoría de los casos, del primer o segundo molar. El síntoma más común que provoca es una sinusitis aguda, que evolucionará a la cronicidad si la fístula permanece. El diagnóstico se realiza mediante endoscopia transalveolar, ortopantografía o tomografía computarizada dental. Su cierre quirúrgico es necesario cuando la fístula tiene más de 3 mm, o no sella por sí misma en 3 semanas. Existen, para ello, varias técnicas, usando distintos materiales y colgajos, cuyo fin es ocluir, tanto el defecto óseo, como el mucoso, para solucionar así a la vez la fístula y el problema sinusal.The oroantral fistula is a solution of pathological continuity between the maxillary sinus and the oral cavity, frequently produced after a teeth extraction in most of cases of the first or second molars. The commonest symptom provoked is an acute sinusitis evolving to chronicity if the fistula remains. The diagnosis is made by transalveolar, orthopantography or dental computerized tomography. Its surgical closure is necessary when the fistula has more than 3 mm or not seal by itself in three weeks. For it, there are some techniques using different materials and flaps where its objective is to occlude the bone defect as well as the mucous one thus solving the fistula and the sinus problem.

Utilidade do Ultrassom intracardíaco no isolamento de veias pulmonares usando cateter-balão a laser Utilidad del ultrasonido intracardíaco en el aislamiento de venas pulmonares usando catéter-balón láser Utility of intracardiac ultrasound imaging to guide pulmonary vein ablation using laser balloon catheter

Directory of Open Access Journals (Sweden)

Luiz Leite

2009-12-01

Full Text Available FUNDAMENTO: O isolamento das veias pulmonares (IVP tem sido usado como endpoint para a ablação da fibrilação atrial (FA com cateter balão. OBJETIVO: Determinar a utilidade do ultrassom intracardíaco (USIC para guiar o IVP, usando cateter balão a laser. MÉTODOS: 59 VP foram ablacionadas em 27 cães. Imagens de Doppler foram usadas para identificar os vazamentos do fluxo sanguíneo entre a VP e o balão. Após cada liberação de energia, o cateter de mapeamento circular foi reposicionado para verificar se o isolamento tinha sido obtido. A posição de vazamento foi então correlacionada com a posição do gap no estudo patológico. A análise de regressão logística multivariada foi realizada. RESULTADOS: Cinquenta e nove VP foram submetidas à ablação. O tempo médio de energia liberada foi de 279±177 seg., o diâmetro médio do balão era de 23±3 mm, e o comprimento médio do balão era 25±4 mm. O isolamento completo foi obtido em 38/59 (64%, e foi significantemente mais comum sem vazamento: [30/38 (79% versus 8/23 (35%, pFUNDAMENTO: Se usó el aislamiento de las venas pulmonares (AVP como endpoint para la ablación de la fibrilación atrial (FA con catéter-balón. OBJETIVO: Determinar la utilidad del ultrasonido intracardíaco (USIC para guiar el AVP, usando catéter-balón láser. MÉTODOS: Se ablacionaron 59 VP en 27 perros. Se usaron imágenes de Doppler para identificar los derrames del flujo sanguíneo entre la VP y el balón. Tras cada liberación de energía, se reposicionó el catéter de mapeamiento circular para verificar si se obtuvo el aislamiento. Se correlaccionó, entonces, la posición del derrame con la posición del gap en el estudio patológico. Se realizó el análisis de regresión logística multivariada. RESULTADOS: Se sometieron 59 VP a la ablación. El tiempo promedio de energía liberada fue de 279±177 seg., el diámetro promedio del balón era de 23±3 mm, y la largura promedio del balón era 25±4 mm

El sistema de vigilancia radiológica ambiental en España

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Rosario Salas Collantes

2010-12-01

Full Text Available El sistema de vigilancia radiológica del medio ambiente establecido en España está constituido por varias redes con diferentes objetivos: una red de vigilancia en el entorno de las instalaciones y varias redes de ámbito nacional financiadas y gestionadas por organismos públicos. Los titulares de las instalaciones son los responsables de la realización de sus programas de vigilancia radiológica ambiental siguiendo las directrices del Consejo de Seguridad Nuclear (CSN. Por otra parte, la Dirección General de Protección Civil y Emergencias dispone de una red de alerta a la radiactividad (RAR constituida por más de 900 estaciones automáticas de medida de tasa de dosis distribuidas por el territorio nacional.La Red de Vigilancia Radiológica Ambiental (Revira, gestionada por el CSN, de ámbito nacional, consta de una red de estaciones de muestreo (REM y una red de estaciones automáticas de medida en continuo (REA. Las comunidades autónomas de Valencia, Cataluña, Extremadura y País Vasco disponen de sus propias redes automáticas similares a la del CSN. Revira proporciona información radiológica sobre la radiactividad de la atmósfera, del suelo, de las aguas (potables, continentales y marinas y de los alimentos. Los programas de muestreo y análisis radiológico se adaptan a las recomendaciones que establece la Comisión de la Unión Europea. La REM cuenta con la colaboración de laboratorios de universidades y con el Centro de Inves- tigaciones Energéticas, Medio Ambientales y Tecnológicas (CIEMAT para su ejecución. La vigilancia de las aguas continentales y costeras la realiza el Centro de Estudios y Experimentación de Obras Públicas del Ministerio de Fomento (CEDEX.

The CSN hosts the Second International Conference on Nuclear Security in Madrid; El CSN acoge en Madrid la Segunda Conferencia Internacional de Seguridad Fisica Nuclear

Energy Technology Data Exchange (ETDEWEB)

Scialdone Garcia, A.

2016-08-01

The second International Conference on Nuclear Security was held in Madrid between May 9th and 13th last. The acting Minister of the Interior announced that the number of officers of the Guardia Civil watching over the Spanish nuclear power plants will be doubled. (Author)

Reconstruction of 3d video from 2d real-life sequences

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Eduardo Ramos Diaz

2010-01-01

Full Text Available En este artículo, se propone un método novedoso que permite generar secuencias de video en 3D usando secuencias de video reales en 2D. La reconstrucción de la secuencia de video en 3D se realiza usando el cálculo del mapa de profundidad y la síntesis de anaglifos. El mapa de profundidad es formado usando la técnica de correspondencia estéreo basada en la minimización de la energía de error global a partir de funciones de suavizado. La construcción del anaglifo es realizada usando la alineación del componente de color interpolándolo con el mapa de profundidad previamente formado. Adicionalmente, se emplea la transformación del mapa de profundidad para reducir el rango dinámico de los valores de disparidad, minimizando el efecto fantasma mejorando la preservación de color. Se usaron numerosas secuencias de video a color reales que contienen diferentes tipos de movimientos como traslacional, rotacional, acercamiento, y la combinación de los anteriores, demostrando buen funcionamiento visual de la reconstrucción de secuencias de video en 3D propuesta.

Efficient hardware implementation of a full COFDM processor with robust channel equalization and reduced power consumption

Directory of Open Access Journals (Sweden)

Alexander López Parrado

2013-01-01

Full Text Available Este trabajo presenta el diseño de un procesador banda-base para multiplexación por división de frecuencias ortogonales codificada (COFDM de 12 Mb/s para el estándar IEEE 802.11a. El procesador COFDM banda- base fue diseñado usando circuitos diseñados por nosotros para corrección de fase de portadora, sincronización de tiempo de símbolo, ecualización de canal robusta y decodificación Viterbi. Estos circuitos son flexibles, parametrizados y descritos usando VHDL estructural y genérico. El procesador COFDM banda- base tiene dos dominios de reloj para reducción del consumo de potencia, fue sintetizado sobre un FPGA Stratix II y fue probado experimentalmente usando circuitería de radio frecuencia (RF a 2.4 GHz.

NUMERICAL STUDY OF APPLE COOLING IN TANDEM ARRANGEMENT

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MARCIO ARÊDES MARTINS

2011-01-01

Full Text Available El enfriamiento conjugado de manzanas dispuestas en tándem en bandejas fue estudiado en este trabajo usando una simulación numérica en CFD. Las ecuaciones gobernantes fueron discretizadas y resueltas usando el método de volúmenes fi nitos sobre mallas no estructuradas triangulares, y fue propuesto un esquema de acoplamiento de transferencia de calor entre la parte sólida y fl uida. El modelo computacional fue validado usando el número de Nusselt local y Nusselt promedio que son reportados en la literatura. La variación del numero de Nusselt y de la distribución de temperatura en las manzanas, fueron encontrados debido al comportamiento conjugado del problema. La aproximación conjugada demostró ser una gran herramienta para optimizar correlaciones convectivas de transferencia de calor reportadas en la literatura.

Development of novel encapsulated formulations using albumin-chitosan as a polymer matrix for ocular drug delivery

Science.gov (United States)

Addo, Richard Tettey

Designing formulations for ophthalmic drug delivery is one of the most challenging endeavors facing the pharmaceutical scientist due to the unique anatomy, physiology, and biochemistry of the eye. Current treatment protocols for administration of drugs in eye diseases are primarily solution formulations, gels or ointments. However, these modes of delivery have several drawbacks such as short duration of exposure, need for repeated administrations and non-specific toxicity. We hypothesize that development of ocular drugs in microparticles will overcome the deficiencies of the current modalities of treatment. We based the hypothesis on the preliminary studies conducted with encapsulated tetracaine, an anesthetic used for surgical purposes and atropine, a medication used for several ophthalmic indications including mydriatic and cycloplegic effects. However, atropine is well absorbed into the systemic circulation and has been reported to exert severe systemic side effects after ocular administration (Hoefnagel D. 1961, Morton H. G. 1939 and Lang J. C. 1995) and may lead to serious side effects including death in extreme cases with pediatric use. Based on these observations, the focus of this dissertation is to formulate microparticulate drug carrier for treatment of various conditions of the eye. Purpose: To prepare, characterize, study the in vitro and in vivo interaction of albumin-chitosan microparticles (BSA-CSN MS), a novel particulate drug carrier for ocular drug delivery. Method: Microparticle formulations were prepared by method of spray drying. The percentage drug loading and efficiency were assessed using USP (I) dissolution apparatus. Using Malvern Zeta-Sizer, we determined size and surface charge of the fabrication. Surface morphology of the microparticles was examined using Scanning Electron Microscopy. Microparticles were characterized in terms of thermal properties using Differential Scanning Calorimetry. Human corneal epithelial cells (HCET-1) were

Avaliação genética de touros usando produção em lactações completas ou parciais projetadas: 3. Confiabilidade e ganhos genéticos

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Melo Cláudio Manoel Rodrigues de

2000-01-01

Full Text Available Para estudar a viabilidade de se usarem produções em lactações parciais, projetadas, na avaliação do mérito genético de touros, foram utilizadas 4595 lactações de 2254 vacas, filhas de 145 touros de 1618 matrizes, distribuídas em 18 rebanhos, com partos entre 1980 e 1997. A partir de 91, 151, 211 ou 241 dias de lactação, projetaram-se 10, 30, 50 ou 70% das lactações, para a duração da lactação observada e para 305 dias. As estimativas dos parâmetros genéticos foram obtidas pelo sistema MTDFREML. Incluíram-se no modelo, independente da característica, efeitos fixos de rebanho-ano, época de parto e idade da vaca ao parto, com termos linear e quadrático, considerando-se efeitos aleatórios de animal, efeito permanente de ambiente e erro. A média das confiabilidades, obtida por meio das produções estimadas (PE, variou de 0,60 a 0,67, utilizando-se P305 igual a 0,60. O ganho genético anual pela seleção dos touros utilizando as PE foi, em média, 24,27% maior que o ganho genético anual da P305, quando as lactações foram projetadas para a duração da lactação observada, e 25,65% superior, quando as lactações foram projetadas para P305. As confiabilidades obtidas, bem como os ganhos genéticos anuais estimados nas avaliações genéticas, usando as PE, foram semelhantes àquelas obtidas para a produção de leite até 305 dias.

Radiological protection in industrial gamma scintigraphy facilities

International Nuclear Information System (INIS)

Rodriguez, M.; Suarez, S.

2002-01-01

Operational experience has shown that the mobile scintigraphy sector is not only that where individual doses are highest but also where there are the greatest number of high doses, overdoses and incidents. This fact highlights the need for improvement in the optimisation of radiological protection in the sector. In this context the CSN has adopted and implemented an action plan aimed at reducing doses to operation staff. (Author)

Scope and implementation of standards ASME N510 / N511 in air treatment system (HVAC) of the Asco nuclear power plant; Alcance e implementacion de las normas ASME N511 en el sistema de tratamiento de aire (HVAC) de la central nuclear de Asco

Energy Technology Data Exchange (ETDEWEB)

Jaimot Jimenez, J. J.

2013-07-01

With the ITC for renewal of license units 1 and 2 of Asco, the CSN It required the commissioning tests underway in the air, according to ASME N510 filter units. It is required that, for safety-related units, to undertake preventive inspections according to ASME N511. All these requirements, in tight deadlines, have represented a great challenge for the organizations of maintenance and engineering of ANAV.

Optimizing the throughput capacity of torpedo ladles with Al{sub 2} O{sub 3}-C-Sic refractories in Brazil; Aumento da disponibilidade e capacidade de carros torpedo revestidos com refratarios de Al{sub 2}O{sub 3}-C-SiC no Brazil

Energy Technology Data Exchange (ETDEWEB)

Lopes, Alvaro Bravo; Braha, Joao; Frasson, Silvio Cassavia [Carborundum do Brasil Ltda. (Brazil); Marques, Oscar Rosa; Delgado, Paulo Roberto Senna [Companhia Siderurgica Nacional, Volta Redonda, RJ (Brazil)

1996-12-31

This paper describes the excellent results of the development program made between Companhia Siderurgica Nacional (C.S.N.) and Carborundum do Brasil Ltda, to improve the throughput capacity of torpedo car ladle by using Al{sub 2} O{sub 3}-C-Sic refractories in Brazil. The development and application of these products are described and presented compared to conventional material currently in use. (author) 11 refs., 10 figs., 2 tabs.

RECONSTRUCCIÓN DE HOLOGRAMAS DE MICROSCOPÍA HOLOGRÁFICA DIGITAL EN LÍNEA A VELOCIDAD DE VIDEO

Directory of Open Access Journals (Sweden)

CARLOS TRUJILLO

2012-01-01

Full Text Available La Microscopía Holográfica Digital en Línea (MHDL es quizás la metodología más simple para obtener información del mundo micrométrico: una fuente puntual y un dispositivo de registro digital es el equipo necesario. En esta técnica de microscopía, la recuperación de la amplitud compleja esparcida por el espécimen bajo estudio, se hace por medio de algoritmos muy robustos operando sobre registros bidimensionales de intensidad, que contienen millones de pixeles; el tiempo requerido para llevar a cabo este procesamiento de información ha limitado las aplicaciones de la MHDL. Usando la capacidad de cómputo que proveen las unidades de procesamiento gráfico (GPU unido a un número reducido de operaciones, en este artículo se presenta una metodología para la reconstrucción numérica de hologramas a velocidad de video adquiridos en MHDL. Esta estrategia permite la reconstrucción de hologramas de 1 megapixel a 32 cuadros por segundo sin cambiar el desempeño de la MHDL en términos de la resolución espacial de esta arquitectura de microscopía. Los resultados experimentales presentados de reconstrucción un holograma registrado de una monocapa bidimensional auto-organizada de esferas de tamaño micrométrico, revelan las capacidades tridimensionales de la MHDL operando a velocidad de video.

Estudio comparativo de la determinación del tamaño de partícula por dos métodos : tamizado en seco y disfracción láser

Directory of Open Access Journals (Sweden)

Diana Míguez Carames

2011-05-01

Full Text Available El objetivo de este trabajo fue comparar el desempeño analítico de la tecnología de medición de tamaño de partícula por difracción láser con la técnica clásica de tamizado en seco para partículas superiores a 80 micras. Se utilizó arena como muestra de referencia interna. El procedimiento mecánico se realizó con equipo vibrador de tamices durante 15 minutos y batería de tamices estándar ASTM números 20, 40, 70 y 170. La determinación por difracción tri-laser, que implica hacer incidir tres haces de luz láser sobre la partícula, permite evaluar las dimensiones y realizar una distribución de tamaños generada por frecuencias de datos dispuestas en rangos. La muestra tamizada se reconstituyó uniendo sus porciones y se cuarteó por separador rotativo de alta exactitud y reproducibilidad. Una muestra representativa se suspendió en agua con agitación mecánica y los datos de las medidas se representaron gráficamente usando el software del equipo. Se realizaron 10 réplicas por cada método para evaluarlos estadísticamente mediante los métodos de los momentos y Falk y Ward. Se concluye que ambos clasifican la muestra de la mismaforma pero existen diferencias en los coeficientes de curtosis para las distribuciones de las poblaciones según una y otra técnicas.

Historia, severidad de caries y necesidades de tratamiento periodontal en estudiantes de odontología de Cartagena

Directory of Open Access Journals (Sweden)

Katherine Margarita Arrieta Vergara

2012-01-01

Full Text Available Objetivo: Determinar historia, severidad de caries y necesidades de tratamiento periodontal y su relación con variables demográficas en estudiantes de odontología. Materiales y métodos: Estudio descriptivo transversal en una muestra probabilística de 221 estudiantes de odontología de una universidad pública de Cartagena. Se hicieron mediciones clínicas a través de los índices COP, ICDAS II, INTCP, higiene oral simplificado de Green y Vermillion. Se realizó análisis univariado y bivariado usando razones de disparidad y prueba estadística χ2 para la significancia estadística. Resultados: El promedio del COP-D fue de 4,2 y la severidad de caries COP ≤ 6 fue de 77,3% y COP >7 de 22,6%. En cuanto al tratamiento periodontal, los participantes necesitan: instrucción de higiene oral y motivación (29,4%, detartraje supragingival, profilaxis, higiene oral, motivación (22,6%, tratamiento complejo, profilaxis, higiene oral y motivación (41,1%. El análisis de razones de disparidad mostró asociación entre la higiene oral y la severidad de caries (OR=3,3 y enfermedad periodontal (OR=2,9. Conclusiones: Dada la carga de morbilidad en salud oral en esta población, se hace necesario implementar políticas que faciliten y fortalezcan una cultura de prevención y promoción en salud desde el ámbito universitario.

Reducciones temporales para convertir la sintaxis abstracta del diagrama de flujo de tareas no estructurado al álgebra de tareas

Directory of Open Access Journals (Sweden)

Carlos Alberto Fernández-y-Fernández

2015-12-01

Full Text Available Este artículo describe nuestro trabajo en el modelado de software usando reducciones temporales para representar diagramas de flujo no estructurado, como una representación intermedia para construir una expresión textual en una álgebra de procesos particular. Este trabajo fue realizado para poder construir una herramienta CASE de apoyo para la fase del modelado de tareas en el Método Discovery para el desarrollo de software. Inicialmente explicaremos las similitudes entre dos tipos de diagramas, el diagrama de actividades de UML y el diagrama de flujo de tareas con su representación formal (el álgebra de tareas. Posteriormente, ofreceremos una explicación explicando la generación automática, usando las reducciones temporales, de expresiones en el álgebra de tareas usando información abstracta que es obtenida de los diagramas de flujo de tareas.

Evaluation of a Heating System in Poultry Houses Using a CFD Model / Evaluación de un Sistema de Calefacción en Galpones Avicolas Usando un Modelo en CFD

Directory of Open Access Journals (Sweden)

Flávio Alves Damasceno

2014-06-01

Full Text Available Abstract.. The objective of this study was to adapt and validate a computer model using the Computational Fluid Dinamics (CFD, in the prediction of temperature and air speed in a duct distribution system coupled to a heating furnace that is used in typical poultry houses in tropical and subtropical countries. The validation of the model with experimental data was satisfactory, presentingnormalized mean square error NMSE values of 0.25 and 0.02 for air temperature and air speed, respectively. The results evidenced that the proposed model is adequate for predicting the air speed and temperature for this type of system, and could be used to improve the efficiency of the distribution of heat inside and around air ducts using different air speeds, types of materials and dimensions. / Resumen. El objetivo de este estudio fue adaptar y validar un modelo computacional haciendo uso de la dinámica de fluidos computacional (CFD para predecir la temperatura y la velocidad del aire en un sistema de distribución de ductos acoplado a un sitema de calefacción que es utilizado en las instalaciones avícola en los países tropicales y subtropicales. La validación del modelo con los datos experimentales fue satisfactoria, presentando valores medios normalizados del error cuadrado NMSE de 0,25 y 0,02 para la temperatura y velocidad del aire respectivamente. Los resultados muestran que el modelo propuesto es adecuado para predecir la velocidad del aire y la temperatura alrededor de este tipo de sistema, y podría ser utilizado para mejorar la eficiencia la distribución de calor en el interior y alrededor de los conductos, usando diferentes velocidades, tipos de materiales y dimensiones. 

Capas de SiGe policristalino hidrogenado y su aplicación en transistores de película delgada

Directory of Open Access Journals (Sweden)

Rodríguez, A.

2004-04-01

Full Text Available The hydrogenation of polycrystalline SiGe layers, obtained by solid phase crystallization, by an electron ciclotron resonance hydrogen plasma and the influence of this hydrogenation process on the electrical characteristics of thin film transistors fabricated using this material as active layer have been studied. The hydrogenation processes were carried out at 150 and 250 ºC for several times, up to 11 hours. Infrared transmission spectra of these samples show only the absorption bands corresponding to Si-H bonds, indicating that hydrogen atoms are bonded mainly to silicon atoms. Ultraviolet reflectance measurements show that the surface damage caused by the plasma exposure increases as the Ge content of the film does. The transistors fabricated using polycrystalline SiGe films as active layer show a degradation phenomenon, consisting of a progressive decrease of the drain current at constant gate and drain bias. The degradation slows down as the hydrogenation time increases at constant temperature.

En este trabajo se ha caracterizado el proceso de hidrogenación en un plasma generado por resonancia ciclotrónica de electrones de capas de SiGe policristalino obtenidas mediante cristalización en fase sólida y el efecto de la hidrogenación en las características eléctricas de transistores de película delgada fabricados usando dicho material. Los procesos de hidrogenación se realizaron a 150 y 250 ºC, con duraciones de hasta 11 horas. Los espectros de transmitancia en infrarrojo muestran solamente las bandas de absorción características de los enlaces Si-H. Estas bandas indican que el hidrógeno se incorpora al material enlazándose principalmente con los átomos de silicio. Las medidas de reflectancia en el ultravioleta indican que se crea daño en la superficie de la muestra y que éste aumenta a medida que lo hace el contenido en Ge. Los transistores de película delgada con capa activa de SiGe policristalino muestran un fen

Structure and development of cortical bundles in Couroupita guianensis Aubl. (Lecythidaceae)

OpenAIRE

Rajput, Kishore Shankarsinh; Patil, Vidya Shivram

2016-01-01

Estructura y desarrollo de haces corticales en Couroupita guianensis Aubl. (Lecythidaceae) El desarrollo de haces corticales, en ramas y pedúnculos de Couroupita guianensis (Lecythidaceae), comienza cerca del meristemo apical concomitante con los haces vasculares normales. Cada haz cortical llega a estar rodeado por una vaina de fibras que, a menudo, mostraba la presencia de una capa gelatinosa (fibras G). A medida que avanza el crecimiento, cada haz se puede dividir en d...

Validation of a new technique to detect Cryptosporidium spp. oocysts in bovine feces.

Science.gov (United States)

Inácio, Sandra Valéria; Gomes, Jancarlo Ferreira; Oliveira, Bruno César Miranda; Falcão, Alexandre Xavier; Suzuki, Celso Tetsuo Nagase; Dos Santos, Bianca Martins; de Aquino, Monally Conceição Costa; de Paula Ribeiro, Rafaela Silva; de Assunção, Danilla Mendes; Casemiro, Pamella Almeida Freire; Meireles, Marcelo Vasconcelos; Bresciani, Katia Denise Saraiva

2016-11-01

Due to its important zoonotic potential, cryptosporidiosis arouses strong interest in the scientific community, because, it was initially considered a rare and opportunistic disease. The parasitological diagnosis of the causative agent of this disease, the protozoan Cryptosporidium spp., requires the use of specific techniques of concentration and permanent staining, which are laborious and costly, and are difficult to use in routine laboratory tests. In view of the above, we conducted the feasibility, development, evaluation and intralaboratory validation of a new parasitological technique for analysis in optical microscopy of Cryptosporidium spp. oocysts, called TF-Test Coccidia, using fecal samples from calves from the city of Araçatuba, São Paulo. To confirm the aforementioned parasite and prove the diagnostic efficiency of the new technique, we used two established methodologies in the scientific literature: parasite concentration by centrifugal sedimentation and negative staining with malachite green (CSN-Malachite) and Nested-PCR. We observed good effectiveness of the TF-Test Coccidia technique, being statistically equivalent to CSN-Malachite. Thus, we verified the effectiveness of the TF-Test Coccidia parasitological technique for the detection of Cryptosporidium spp. oocysts and observed good concentration and morphology of the parasite, with a low amount of debris in the fecal smear. Copyright © 2016 Elsevier B.V. All rights reserved.

Efficient sampling of complex network with modified random walk strategies

Science.gov (United States)

Xie, Yunya; Chang, Shuhua; Zhang, Zhipeng; Zhang, Mi; Yang, Lei

2018-02-01

We present two novel random walk strategies, choosing seed node (CSN) random walk and no-retracing (NR) random walk. Different from the classical random walk sampling, the CSN and NR strategies focus on the influences of the seed node choice and path overlap, respectively. Three random walk samplings are applied in the Erdös-Rényi (ER), Barabási-Albert (BA), Watts-Strogatz (WS), and the weighted USAir networks, respectively. Then, the major properties of sampled subnets, such as sampling efficiency, degree distributions, average degree and average clustering coefficient, are studied. The similar conclusions can be reached with these three random walk strategies. Firstly, the networks with small scales and simple structures are conducive to the sampling. Secondly, the average degree and the average clustering coefficient of the sampled subnet tend to the corresponding values of original networks with limited steps. And thirdly, all the degree distributions of the subnets are slightly biased to the high degree side. However, the NR strategy performs better for the average clustering coefficient of the subnet. In the real weighted USAir networks, some obvious characters like the larger clustering coefficient and the fluctuation of degree distribution are reproduced well by these random walk strategies.

Innovaciones en la gestión y calidad de los revestimientos refractarios en la Compañía Siderúrgica Nacional (Brasil

Directory of Open Access Journals (Sweden)

Justus, S. M.

2002-04-01

Full Text Available The work describes actions carried out in colaboration among the National Steel Company - (CSN-Brazil and the Interdisciplinary Laboratory of Electrochemistry and Ceramic - LIEC of the Federal University of Sao Carlos Brazil (UFSCar- Brazil, in the area of I&D, for integral management and improvement of the quality and performance of the refractory linings in the sintering areas, blast furnace, hot air pipe lines transferency to the blast furnace, pig-iron ladles, running channels, blast furnaces hearths, torpedo car, etc., as well as, the economic impact generated by the installation of the adopted measures.

El trabajo describe acciones realizadas en conjunto entre la Compañía Siderúrgica Nacional – (CSN-Brasil y el Laboratorio Interdisciplinar de Electroquímica y Cerámica – LIEC de la Universidad Federal de Sao Carlos Brasil (UFSCar - Brasil, en el área de I&D, para la gestión y mejora de la calidad de los revestimientos refractarios en las áreas de sinterización, hornos altos, líneas de trasferencia de aire caliente al horno alto, piqueras de arrabio, canales de colada, crisoles de horno alto, cucharas torpedo, etc., así como, el impacto económico generado por la implantación de las medidas adoptadas.

Characterization of the adhesion of thin film by Cross-Sectional Nanoindentation. Analysis of the substrate edge chipping and the film delamination

Science.gov (United States)

Felder, Eric; Roy, Sébastien; Darque-Ceretti, Evelyne

2011-07-01

Cross-Sectional Nanoindentation (CSN) is a recent method for adhesion measurement of nanoscale thin films in Ultra-Large Scale Integrated circuits. In the case of ductile thin films, the motion of the substrate chip implies significant plastic deformation of the film and complex geometry of delaminated areas. This article recalls first the experimental procedure and the two main features observed in this test performed on various plane copper films deposited on silicon: the critical force producing silicon edge chipping increases linearly with the distance of the indenter to the interface; on the section the delaminated length of the film ( a-b) is proportional to the residual silicon chip displacement u and the ratio S=u/(a-b) depends on the manufacturing process of the film, and is so related to its adhesion to the substrate. One proposes a simple analysis of the silicon edge chipping. Then a model of pull-off of an elastic-strain hardening plastic film is developed, which suggests an explanation for the delamination process. Application of the model to experimental results starting from films plastic properties deduced from nanoindentation measurements provides plausible results. Some improvements for performing the CSN test are proposed in order to make easier its interpretation.

Análisis longitudinal desde imágenes de resonancia magnética para la detección temprana de la enfermedad del Alzheimer

OpenAIRE

Lin, Lin

2017-01-01

Alzheimer es una enfermedad neuro-degenerativa, la atrofia de algunas estructuras subcorticales se puede observar en los pacientes de Alzheimer usando neuroimagen. En este proyecto, se estudiará la atrofia de algunas sub-estructuras corticales para obtener bio-marcadores de esa enfermedad usando MRI-T1 y DTI. MRI estructural es sensible a los cambios de materias grises y el hipocampo es un marcador potente de la enfermedad. Se realizará una segmentación longitudinal de imágenes de resonancia ...

¿Hace falta una política industrial en México?

OpenAIRE

Pablo Mejía Reyes

2002-01-01

Se presentan argumentos teóricos y empíricos para justificar la implementación de una política industrial en México. Se sostiene que las fallas de mercado vinculadas a la generación de tecnología y de barreras a la entrada y a la salida provocan rezagos tecnológicos, bajo nivel de competitividad internacional y concentración económica, lo que dificulta la inserción en la economía internacional y en la transmisión de los beneficios del crecimiento hacia un mayor bienestar en la población....

On the structure and variation of 'hace' as a temporal expression

African Journals Online (AJOL)

have finished the thesis make.fut one ... specifier of this degree phrase, equivalent to the measure phrase in ... the standard representation of the dialogue between Aktionsart – at the vP level – and ...... Ms., Universitat Autònoma de Barcelona.

External proton and Li beams; Haces externos de protones y litios

Energy Technology Data Exchange (ETDEWEB)

Schuff, Juan A; Burlon, Alejandro A; Debray, Mario E; Kesque, Jose M; Kreiner, Andres J; Stoliar, Pablo A; Naab, Fabian; Ozafran, Mabel J; Vazquez, Monica E [Comision Nacional de Energia Atomica, General San Martin (Argentina). Dept. de Fisica; Policastro, Lucia L; Duran, Hebe; Molinari, Beatriz L; O' Connor, Silvia E; Saint-Martin, Maria L.G.; Palmieri, Monica; Bernaola, Omar A; Opezzo, Oscar J [Comision Nacional de Energia Atomica, General San Martin (Argentina). Dept. de Radiobiologia; Mazal, A; Favaudon, F; Henry, Y [Institut Curie, 75 - Paris (France); Perez de la Hoz, A.; Somacal, Hector; Valda, Alejandro; Canevas, S; Ruffolo, M; Tasat, D R [Universidad Nacional de General San Martin, Villa Ballester (Argentina). Escuela de Ciencia y Tecnologia; Davidson, Miguel; Davidson, Jorge [Buenos Aires Univ. (Argentina). Dept. de Fisica; Delacroix, S; Nauraye, C; Brune, E; Gautier, C; Habrand, J L [Centre de Protontherapie, 91 - Orsay (France); Muhlmann, M C [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires (Argentina)

2000-07-01

In the frame of a feasibility study to introduce proton therapy in Argentina in a collaborative agreement between the Physics and Radiobiology Departments of the National Atomic Energy Commission or Argentina and the Centre de Protontherapie de Orsay, France, external proton and Li beams were produced at the TANDAR accelerator in Buenos Aires. The specific aim of this work was to start radiobiology studies on cell cultures and small laboratory animals. In particular we seek to determine here the relative biological effectiveness, RBE, for proton and Li beams as a function of energy for different tumor and normal cell lines. The 24 MeV proton beam was diffused using a 25 {mu}m gold foil and extracted through a Kapton window to obtain a homogeneous field (constant to 95%) of about 7 cm in diameter. Measurements were carried out with quasi-monoenergetic beams (of 20.2 {+-} 0.07 MeV, 2.9 {+-} 0.10 MeV y 1.5 {+-} 0.1 MeV for protons and 21.4 {+-} 0.4 MeV for Lithium). Proton fluence and Bragg peaks were measured. The dose delivered in each case was monitored on-line with a calibrated transmission ionization chamber. Three cell lines PDV, PDVC 57 and V 79 (as a reference) were irradiated with {gamma}-rays, proton and lithium beams with linear energy transfer (LET) from 2 to 100 keV/{mu}m. RBE values in the range of 1.2-5.9 were obtained. In addition preliminary studies on chromosomal aberrations and viability of alveolar macrophages were carried out. (author)

Análisis de rendimiento académico estudiantil usando data warehouse y redes neuronales Analysis of students' academic performance using data warehouse and neural networks

Directory of Open Access Journals (Sweden)

Carolina Zambrano Matamala

2011-12-01

Full Text Available Cada día las organizaciones tienen más información porque sus sistemas producen una gran cantidad de operaciones diarias que se almacenan en bases de datos transaccionales. Con el fin de analizar esta información histórica, una alternativa interesante es implementar un Data Warehouse. Por otro lado, los Data Warehouse no son capaces de realizar un análisis predictivo por sí mismos, pero las técnicas de inteligencia de máquinas se pueden utilizar para clasificar, agrupar y predecir en base a información histórica con el fin de mejorar la calidad del análisis. En este trabajo se describe una arquitectura de Data Warehouse con el fin de realizar un análisis del desempeño académico de los estudiantes. El Data Warehouse es utilizado como entrada de una arquitectura de red neuronal con tal de analizar la información histórica y de tendencia en el tiempo. Los resultados muestran la viabilidad de utilizar un Data Warehouse para el análisis de rendimiento académico y la posibilidad de predecir el número de asignaturas aprobadas por los estudiantes usando solamente su propia información histórica.Every day organizations have more information because their systems produce a large amount of daily operations which are stored in transactional databases. In order to analyze this historical information, an interesting alternative is to implement a Data Warehouse. In the other hand, Data Warehouses are not able to perform predictive analysis for themselves, but machine learning techniques can be used to classify, grouping and predict historical information in order to improve the quality of analysis. This paper depicts architecture of a Data Warehouse useful to perform an analysis of students' academic performance. The Data Warehouse is used as input of a Neural Network in order to analyze historical information and forecast. The results show the viability of using Data Warehouse for academic performance analysis and the feasibility of

Las tres Marías

Directory of Open Access Journals (Sweden)

2014-09-01

Full Text Available Se llama María N., tiene 83 años, vive sola, nunca se casó. Su único familiar vivo reside en una lejana ciudad. Hace dos años tuvo un ictus. Le ocasiona inestabilidad crónica. Sobrevive porque una vecina la cuida, le hace la compra y la limpieza, y frecuentemente le hace compañía y la invita a comer. Reingresa ahora por otra caída

Consistent adoption of the International System of Units (SI) in nuclear science and technology

Energy Technology Data Exchange (ETDEWEB)

Klumpar, J; Kovar, Z [Ceskoslovenska Akademie Ved, Prague. Laborator Radiologicke Dozimetrie; Sacha, J [Slovenska Akademia Vied, Bratislava (Czechoslovakia). Fyzikalny Ustav

1975-11-01

The principles are stressed behind a consistent introduction of the International System of Units (SI) in Czechoslovakia complying with the latest edition of the Czechoslovak Standard CSN 01 1300 on the prescribed system of national and international units. The use of special and auxiliary units in nuclear physics and technology is discussed, particular attention being devoted to the units of activity and to the time units applied in radiology. Conversion graph and tables are annexed.

The future of energy in the European Union

International Nuclear Information System (INIS)

Robles, C.

1997-01-01

Two of the three European Union founding treaties have a marked energy nature but, however, at the present time, the EU lacks a Common Energy Policy, Starting with this paradox, the European Parliament Member Robles Piquer uses this article, which reproduces the lecture he gave at the CSN, to proffer his view of the future of energy which the EU will have and that which it should have, in this opinion. (Author)

Status of computerization and application in nuclear reactors

International Nuclear Information System (INIS)

Viedma, L.G. de

1997-01-01

The CSN has recently procured a latest generation computer to address its future design requirements. In order to present it to the readers, this articles sets out the concepts of the latest computerization technologies, making historical references to the evolution of the different architectures and different computers with similar performance available on the market. Mention is also made to areas where parallel design is, or may be, highly important in the future. (Author)

Statistical analysis of personal dosimetry of exposed workers

International Nuclear Information System (INIS)

Sanchez Munoz, F. J.; Alejo Luque, L.; Mas Munoz, I.; Serrada Hierro, A.

2013-01-01

The dosimetry centers accredited by the Nuclear Safety Council (CSN) normally report overcoming legal limits, or some fraction thereof, but do not provide comparative dosimetric criteria indicating if assigned to a given dose is large TPE or small relative to that of their peers. In order to help to resolve the difficulties mentioned ds, it has developed an application that statistically processes the dosimetric data provided by the National Dosimetry Center. (Author)

Statistical analysis of personal dosimetry of exposed workers; Analisis estadistico de la dosimetria personal de trabajadores expuestos

Energy Technology Data Exchange (ETDEWEB)

Sanchez Munoz, F. J.; Alejo Luque, L.; Mas Munoz, I.; Serrada Hierro, A.

2013-07-01

The dosimetry centers accredited by the Nuclear Safety Council (CSN) normally report overcoming legal limits, or some fraction thereof, but do not provide comparative dosimetric criteria indicating if assigned to a given dose is large TPE or small relative to that of their peers. In order to help to resolve the difficulties mentioned ds, it has developed an application that statistically processes the dosimetric data provided by the National Dosimetry Center. (Author)

Processamento da rede neocognitron para reconhecimento facial em ambiente de alto desempenho GPU

OpenAIRE

Gustavo Poli Lameirão da Silva

2007-01-01

Neste trabalho é apresentada a implementação da Rede Neural Neocognitron, usando uma arquitetura de computação de alto desempenho baseada em GPU (Graphics Processing Unit). O Neocognitron é uma rede neural artificial, proposta por Fukushima e colaboradores, constituída de vários estágios de camadas de neurônios, organizados em matrizes bidimensionais denominadas planos celulares. Para o processamento de alto desempenho da aplicação de reconhecimento facial usando neocognitron foi utilizado o ...

CSN competence in the new regulations on risk prevention at work

International Nuclear Information System (INIS)

Mendez, V. E.

1999-01-01

This article gives a summary of the paper as submitted by the authoress at the seminar organized by the Spanish Radiological Protection Society for analyzing the implications of the regulations on risk prevention at work in medical surveillance and radiological protection of radiation workers occupationally exposed to ionizing radiations. (Author)

AcuI identifies water buffalo CSN3 genotypes by RFLP analysis

Indian Academy of Sciences (India)

Water buffalo population amounts to 185 million heads. (http://www.fao.org). They are mainly present in Southeast. Asia. Casein genes among other genes control the milk traits in water buffalo. The role of casein genotypes on composi- tion and coagulation of milk, quality and yield traits has been investigated (Lien et al.

Modelado de Materiales Compuestos por Elementos Finitos usando Restricciones Cinemáticas Finite Element Modeling of Composite Materials using Kinematic Constraints

Directory of Open Access Journals (Sweden)

Oscar E. Ruiz

2009-12-01

Full Text Available El propósito de este artículo es presentar simulaciones del comportamiento de materiales compuestos basado en restricciones cinemáticas entre las mismas fibras y entre las fibras y la resina circundante. En la revisión de literatura, los autores han encontrado que las restricciones cinemáticas no han sido plenamente explotadas para modelar materiales compuestos, probablemente debido a su alto costo computacional. El propósito de este articulo es exponer la implementación y resultados de tal modelo, usando Análisis por Elementos Finitos de restricciones geométricas prescritas a los nodos de la resina y las fibras. Las descripciones analíticas del comportamiento de materiales compuestos raramente aparecen. Muchas aproximaciones para describir materiales compuestos en capas son basadas en la teoría de funciones C1Z y C0 Z, tal como la Teoría Clásica de Capas (CLT. Estas teorías de funciones contienen significativas simplificaciones del material, especialmente para compuestos tejidos. Una aproximación hibrida para modelar materiales compuestos con Elementos Finitos (FEA fue desarrollada por Sidhu y Averill y adaptada por Li y Sherwood para materiales compuestos tejidos con polipropileno de vidrio.The purpose of this article is to present simulations of the behavior of composite materials based on kinematic restrictions among the fibers themselves and among fibers and the surrounding resine. In the literature review the authors have found that the kinematic restrictions have not been fully exploited for modeling composite materials, probably due to their high computational expense. The purpose of this article is to show the implementation and results of such a model, by using a Finite Element Analysis of geometric restrictions prescribed to the resine and fiber nodes. Closed analytic descriptions on behavior of layered composite materials are very rare. Many approaches to describe layered composite material are based on the theory of

Utilização do AutoCAD 2004 para quantificação de pesquisas usando fotomicrografias eletrônicas AutoCAD 2004 to quantify electron-photomicrography

Directory of Open Access Journals (Sweden)

Carla Albertina Martins Almeida

2007-08-01

Full Text Available OBJETIVO: Avaliar o uso do programa AutoCAD 2004 para estudos quantitativos em microscopia eletrônica. MÉTODOS: A demonstração da utilização do AutoCAD 2004 foi feita em um modelo experimental de diabetes induzido em ratos, divididos em Grupo Controle (GC-10 animais e Grupo Diabético (GD - 10 animais, avaliados 1 mês depois da indução do diabetes. Os olhos foram removidos após o sacrifício dos animais e preparados para exame em microscópio eletrônico, tendo sido feitas fotografias dos vasos retinianos. Foi utilizado o programa AutoCAD2004 para avaliar a espessura da membrana basal dos vasos. Os resultados foram avaliados estatisticamente. RESULTADOS: Usando o método proposto foi possível realizar medidas quantitativas na membrana basal de vasos retinianos de ratos diabéticos. CONCLUSÃO: O AutoCAD 2004 se mostrou efetivo, seguro e de fácil utilização para a quantificação de fenômenos biológicos, sendo possível sugerir este meio para a realização de avaliações quantitativas em experimentos biológicos.OBJECTIVE: To determine if the AutoCAD 2004 program is available to be used in quantitative research on electron microscopy. METHODS: A demonstrative of the AutoCAD2004 was done in an experimental model of diabetes induced in rats. The animals were divided by lot in control group animals (GC-10 animals and diabetic group (GD - 10 animals, evaluated 1 month after the diabetes induction. The eyes were removed after sacrifice and prepared to electron microscopy. The retina was photographed and the AutoCAD2004 program was used to measure the basal membrane of retina vessels. The results were submitted to statistical analysis. RESULTS: The AutoCAD2004 was effective to obtain quantitative measures from the basal membrane of retina vessels and there were no difference between the studied groups. CONCLUSION: The AutoCAD2004 was effective, safe and easy to apply to quantify biological parameters, which allowed suggest it to

Estabilidade do movimento rotacional de satélites artificiais

OpenAIRE

Regina Elaine Santos Cabette

2006-01-01

Usando uma formulação canônica, neste trabalho é analisada a estabilidade do movimento de rotacional de um satélite artificial que considera perturbações devido ao torque de gradiente de gravidade. Aqui as variáveis de Andoyer são usadas para descrever o movimento de rotacional. Uma das aproximações que permitem a análise da estabilidade de sistemas hamiltonianos necessita da redução da hamiltoniana na forma normal. Primeiramente são encontrados pontos de equilíbrio e usando coordenadas gener...

Desempeño de sensores de campo electrostático en sistemas de alerta de tormentas

OpenAIRE

Aranguren Fino, Harby Daniel

2011-01-01

Esta tesis presenta un estudio operacional y científico de sensores de campo electrostático mediante el análisis de tormentas eléctricas en tres lugares: Colombia (2010), usando una estación de medida en Bogotá; Florida - EE.UU (2009), usando 31 sensores en el Kennedy Space Center - KSC y Navarra - España (2010), con 11 molinos de campo en parques eólicos. En total se analizaron cerca de 67000 medidas de variaciones de campo eléctrico producidas por rayos. En cada sitio se uso adicionalmente ...

Abundancias químicas de ψ Octantis

Science.gov (United States)

Medina, M. C.; Pintado, O. I.

Se determinan las abundancias químicas de ψ Oct usando espectros obtenidos con EBASIM en CASLEO. Los valores iniciales de temperatura efectiva y gravedad superficial se calculan con la fotometría uvbyβ. Esta estrella fue estudiada por Pintado y Adelman (1996) usando espectros REOSC y Adelman y otros (1993), este último basado en espectros echelle obtenidos con el Telescopio Anglo Australiano. Comparamos nuestros resultados con los de los trabajos anteriormente mencionados, pudiéndose realizar una evaluación de la calidad de los espectros EBASIM.

Desarrollo de un sistema basado en la visión artificial para el reconocimiento de placas vehiculares

OpenAIRE

Suárez Pino, José Antonio; Suárez Pino, José Antonio; Suárez Pino, José Antonio

2011-01-01

El presente trabajo describe el desarrollo del sistema de reconocimiento de placas vehiculares basado en visión artificial. En primer lugar, la placa es detectada dentro de la imagen digital usando las características de ancho, altura y área de los objetos que hay en la imagen. Después de ubicar la placa, los caracteres son extraídos de la imagen uno a uno. Finalmente, cada carácter es reconocido usando el algoritmo de redes neuronales artificial. Las pruebas de reconocimiento se realizaron t...

Estudio del desgaste por deslizamiento en bronces

OpenAIRE

Carlos Holguín; John Coronado

2007-01-01

Se evaluaron tres bronces: SAE 67, nacional y americano usados típicamente como material de la chumacera en los molinos de caña de azúcar. Se realizaron pruebas desgaste por deslizamiento bajo la norma G77 usando bloques de bronce, anillos de acero SAE 1045 y aceite como lubricante. El tribómetro se calibró usando los anillos de acero SAE 4620 y se usó acero de herramienta SAE O1 para los bloques. Se realizaron metalografías, durezas y rugosidad de los materiales estudiados. El bronce naciona...

Characterization of Alien isoforms in vertebrates : Caracterización de isoformas de Alien en vertebrados

OpenAIRE

Tenbaum, Stephan

2002-01-01

Alien protein isoforms have been described to be involved in a number of biological processes. Alienalpha is a corepressor of the thyroid hormone receptor mediating transcriptional repression in a ligand-sensitive manner. Furthermore, Alienalpha is a corepressor for the orphan receptor DAX1 and the vitamin-D3 receptor. Alienbetta/CSN2 is part of the COP9-signalosome complex that acts in protein phosphorylation, protein degradation and cell cycle regulation. The major goal of this...

Process for evaluation of renewal of the operating permit for Garona NPP

International Nuclear Information System (INIS)

Zarzuela Jimenez, J.

2009-01-01

Process for evaluation of renewal of the operating permit for Garona NPP. The Santa Maria de Garona nuclear power plant has requested the renewal of its operating permit for a period of ten years, this implying extension of the operating lifetime of the facility beyond the 40 years originally established. This article explains the process of evaluation that the CSN is carrying out in order to draw up a report on the technical feasibility of this proposal. (Author)

Improvements in emergency management in nuclear power plants after the Fukushima accident: ORE, CAE and CAGE; Mejoras en la gestion de emergencias en centrales nucleares tras el accidente de Fukushima: ORE, CAE y CAGE

Energy Technology Data Exchange (ETDEWEB)

Gimenez Gonzalez, S.; Sanchez Lombardia, A.; Martin Calvarro, J. M.; Calvin Cuartero, M.

2016-08-01

After Fukushima accident European NPP safety was checked by means of homogenous stress test promoted by European council. At Spain CSN issued Technical instructions to confirm safety NPP margins were appropriate . As a result of this assessment licensees promoted improving NPP safety by strengthen ERO; a new Support Emergency center (CAE) and construction of a new alternative management centre (CAGE) at each site. European countries have been improving and reinforced NPP safety in a similar way to Spain. (Author)

Incidents of melting CS-137 sources in the Arcelor Mittal OlaberrIa and Arcelor Mittal Zumarraga. Waste management; Incidentes de fusion de fuentes de Cs-137 enlas plantas de Arcelor Mittal Olaberria y Arcelor Mittal Zumarraga. Gestion residuos

Energy Technology Data Exchange (ETDEWEB)

Alcaide Trenas, E.; Ortiz Ramis, T.; Garcia Cadierno, J. P.

2013-07-01

The October 27, 2011, Arcelor Mittal Olaberria notifies the CSN the merger of a source of Cs-137 has been detected in the installation that the flue dust is sent. A few days later the same case happens in Arcelor Mittal Zumarraga. Both plants are companies attached to the Protocol for Radiological Surveillance of Metallic Materials. Both have at the entrance of the installation of systems for detection of radioactive materials that could be among the junk. (Author)

IAEA Mission on the Programme for the rehabilitation of contaminated areas in Japan; Mision del OIEA sobre el Programa de Rehabilitacion de Zonas Contaminadas en Japon

Energy Technology Data Exchange (ETDEWEB)

Lentijo, J. C.

2011-07-01

In October the International Atomic Energy Agency sent an expert mission to gain insight into and assess the rehabilitation programme implemented by the Japanese government to allow for the return of residents to certain areas affected by the accident that occurred at the Fukushima nuclear power plant. The results of this mission, which was led by the CSN Director of Radiological Protection, point to the viability, suitability and seriousness of the project and include suggestions for improvement. (Author)

Facial Anthropometric Norms of the Young Iranian Population.

Science.gov (United States)

Bayat, Mohammad; Shariati, Mahsa; Rajaeirad, Fatemeh; Yekaninejad, Mir Saeed; Momen-Heravi, Fatemeh; Davoudmanesh, Zeinab

2018-06-01

Facial anthropometric measurement is considered an essential concern of surgeons, orthodontists, artists and forensic scientists. The aim of this study is to investigate facial anthropometric norms of the young Iranian population. The study participants consisted of 200 healthy Iranian students (100 males, 100 females) aged 18-25 years old. Twenty-three liner and four angular measurements were investigated twice by a dentist. Independent-samples t test was used to compare indices between males and females and also between countries. A p value less than 0.05 was considered statistically significant. It was found that the mean measurements of c'-sn' of both sides, nasolabial angle, trichion-gnathion, tragion-tragion and gnathion-gnathion were statistically greater in Iranian males than in females ( p  < 0.05). Comparing Iranian anthropometric norms with North American Whites, Malays, Turkish and African American women demonstrated that there were statistically significant differences in most anthropometric measurements between Iranians and other populations ( p  < 0.05). In Iranians, mean measurements of c'-sn' of the right and left sides, nasolabial angle, trichion-gnathion, tragion-tragion and gnathion-gnathion were greater in men than in women. Comparing Iranian males and females with different ethnicities indicated several interracial differences, which should be taken into consideration when dealing with patients or also practitioners originated in this region.

Application of a Software tool for Evaluating Human Factors in Accident Sequences

International Nuclear Information System (INIS)

Queral, Cesar; Exposito, Antonio; Gonzalez, Isaac; Quiroga, Juan Antonio; Ibarra, Aitor; Hortal, Javier; Hulsund, John-Einar; Nilsen, Svein

2006-01-01

The Probabilistic Safety Assessment (PSA) includes the actions of the operator like elements in the set of the considered protection performances during accident sequences. Nevertheless, its impact throughout a sequence is not analyzed in a dynamic way. In this sense, it is convenient to make more detailed studies about its importance in the dynamics of the sequences, letting make studies of sensitivity respect to the human reliability and the response times. For this reason, the CSN is involved in several activities oriented to develop a new safety analysis methodology, the Integrated Safety Assessment (ISA), which must be able to incorporate operator actions in conventional thermo-hydraulic (TH) simulations. One of them is the collaboration project between CSN, HRP and the DSE-UPM that started in 2003. In the framework of this project, a software tool has been developed to incorporate operator actions in TH simulations. As a part of the ISA, this tool permits to quantify human error probabilities (HEP) and to evaluate its impact in the final state of the plant. Independently, it can be used for evaluating the impact of the execution by operators of procedures and guidelines in the final state of the plant and the evaluation of the allowable response times for the manual actions of the operator. The results obtained in the first pilot case are included in this paper. (authors)

Task related doses in Spanish pressurized water reactors over the period 1988-1992

Energy Technology Data Exchange (ETDEWEB)

O`Donnell, P.; Labarta, T.; Amor, I. [Subdireccion de Proteccion Radiologica, Madrid (Spain)

1995-03-01

In order to evaluate in depth the collective dose trend and its correlation with the effectiveness of the practical application of the ALARA principle in Spanish nuclear facilities, and base the different policy lines to promote this criteria, the CSN has fullfilled an analysis of the task related doses data over the period 1988-1992. Previously, the CSN had required to the utilities the compilation of their refuelling outage collective dose from 1988 according with a predeterminate number of tasks, in order to have available a representative and retrospective set of data in an homogeneous way and coherent with the international data banks on occupational exposure in NPP, as the CEC and the NEA ones. The scope of this analysis was the following: first, the collective dose summaries for outage tasks and departments for PWR and for BWR, including the minimum, maximum and average dose (and statistics data) for 18 different refuelling outage tasks and 12 personal departments for each generation of each type of rector, the task and department related collective dose trends in each plant and in each generation, and second, the dose reduction techniques having been used during that period in each plant and the relative level of adoption. In this presentation the main results and conclusions of the first part of the study are reviewed for PWR.

Intermittent water discharges for family orchards using photovoltaic energy and a system self-operating for a TDF; Riego intermitente para huertos familiares usando energia fotovoltaica y un sistema auto-operante para un TDF

Energy Technology Data Exchange (ETDEWEB)

Millan Diaz, Candido; Garcia Villanueva, Nahun H [Instituto Mexicano de Tecnologia del Agua, Jiutepec, Morelos (Mexico); Sanchez Juarez, Aaron [Centro de Investigacion en Energia, UNAM, Temixco, Morelos (Mexico)

2000-07-01

This work present the design of a system for automatic opening and closing of a Discharge Bottom Tank (DBT) to produce intermittent water discharges. In order to modernize and increase the production in the family orchards, the application of a integral system built with a self-operating opening and closing valve, a DBT and a PV water pumping system, is suggested. The results obtained from this integral system, is suggested. The results obtained from this integral system applied in a family experimental farm of 144 m{sup 2} are shown below. The PV system size for pumping the required water per day for that family prototype farm was of 106 W-p. Comparing the yield obtained for green tomato, red tomato, and squash in existing technical irrigation process against our integral system, it is shown that our production is almost the same. [Spanish] En este trabajo se presenta el diseno de un sistema de apertura y cierre automatico para producir descargas de agua intermitentes en un Tanque de Descarga de Fondo (TDF). Con el objeto de aumentar la produccion agricola en los huertos familiares, se sugiere la aplicacion de un sistema integral, para riego intermitente en ellos, formado por: el sistema auto operante disenado, un TDF y un sistema de bombeo fotovoltaico, como una alternativa para modernizar y mejorar las eficiencias del riego por gravedad en ellos. Se dan a conocer los resultados obtenidos de este sistema integral en un huerto familiar experimental de 144 m{sup 2}. El tamano del sistema de bombeo fotovoltaico para extraer el agua requerida por dia-cultivo para ese huerto familiar prototipo fue de 106 W-p. El rendimiento por hectarea obtenido para cultivos de jitomate, tomate y calabacita muestra que nuestra produccion, usando el sistema integral, es comparable con los rendimientos por hectarea que se obtienen con metodologias de riego tecnificadas.

NEURAL NETWORK BASED SYSTEM IDENTIFICATION OF A PMSM UNDER LOAD FLUCTUATION

Directory of Open Access Journals (Sweden)

JABID QUIROGA

2009-01-01

Full Text Available La técnica de redes neuronales es usada para modelar un PMSM. Una red recurrente multicapas predice el componente fundamental de la señal de corriente un paso adelante usando como entradas el componente fundamental de las señales de voltaje y la velocidad del motor. El modelo propuesto de PMSM puede ser implementado en un sistema de monitoreo de la condición del equipo para realizar labores de detección de fallas, evaluación de su integridad o del proceso de envejecimiento de éste. El modelo se valida usando un banco de pruebas para PMSM de 15 hp. El sistema de adquisición de datos es desarrollado usando Matlab®/Simulink® con dSpace® como interfase con el hardware. El modelo mostró capacidades de generalización y un desempeñosatisfactorio en la determinación de las componentes fundamentales de las corrientes en tiempo real bajo condiciones de no carga y fluctuaciones de esta.

Operational exposition and analysis of the inverse problem electroencephalographic; Planteamiento operacional y analisis del problema inverso electroencefalografico

Energy Technology Data Exchange (ETDEWEB)

Fraguela Collar, Andres; Oliveros Oliveros, Jose J.; Ivanovich Grebennikov, Alexandre [Benemerita Universidad Autonoma de Puebla, Puebla (Mexico)

2001-04-01

Techniques of the potential theory have been used to analyze the properties of the operator where the sources of current produced by electric activity in the cerebral cortex is associated with the measurements on the scalp of the electric potential generated by these sources. A medium conductor model which take in account the circle convolution of the brain has been used to prove the uniqueness of solution of the inverse problem of recuperation of activity cortical sources from electroencephalographic measurement on the scalp. This result of uniqueness is very important because we can to use algorithms of regularization. An other state the problem is presented to elaborate numerical solutions of the inverse problem using a set of discrete measurement. The stability of algorithms is showed in some examples. [Spanish] Tecnicas de la teoria de potencial han sido utilizadas para analizar las propiedades del operador que a las fuentes de corriente asociadas a la actividad electrica de las neuronas en la corteza cerebral, le hace corresponder la medicion de potencial electrico generado por dichas fuentes sobre el cuero cabelludo. Un modelo de medio conductor que toma en consideracion las circonvoluciones del cerebro ha sido utilizado para probar la unidad de solucion del problema inverso de recuperacion de las fuentes de actividad cortical a partir de las mediciones electroencefalograficas. Este resultado de unidad es fundamental ya que nos permite aplicar los metodos de regularizacion. Es presentado otro planteamiento del problema que nos permite construir soluciones numericas del problema inverso usando los datos de entrada discretos. La estabilidad de los algoritmos es ilustrada en algunos ejemplos numericos.

Efecto del tratamiento térmico en la morfología y conductividad térmica de cenizas volantes de la combustión de carbón

Directory of Open Access Journals (Sweden)

Gabriel Peña-Rodríguez

2014-07-01

Full Text Available Se presenta el efecto del tratamiento térmico en la conductividad térmica efectiva (ke a temperatura ambiente de polvos de cenizas volantes provenientes de la combustión de carbón de la Central Termoeléctrica de Termotasajero S.A. Dicho parámetro termofísico fue medido usando el sistema KD2Pro® Thermal Properties Analyzer, el cual funciona con el principio físico de flujo lineal transitorio de calor. El tratamiento térmico de las muestras se realizó usando una mufla eléctrica Ney® Vulcan D-130 para el rango de temperaturas de 1050, 1100, 1130, 1200, 1250 y 1300 °C. La porosidad y densidad aparente fue hallada usando la norma NTC 4321-3. La morfología superficial de las muestras fue analizada usando Microscopía Electrónica de Barrido (MEB. Los resultados muestran que a medida que se incrementó la temperatura en el tratamiento térmico, las muestras cambiaron de color de gris oscuro a beige; disminuyó el porcentaje de porosidad, debido a su proceso de vitrificación, y se aumentó la densidad y, por ende, la conductividad térmica efectiva. Los valores reportados de ke son muy importantes en los cálculos del coeficiente de transmitancia térmica en los procesos de transferencia de calor donde se utilicen estas cenizas.

Application of Moessbauer spectroscopy in the study of high temperature oxidation of steel

International Nuclear Information System (INIS)

Seberini, M.; Volenik, K.

1975-01-01

The applicability was tested of etching by solutions of bromine or iodine in methyl alcohol in separating oxide films from substrates to make possible the measurement of absorption spectra. Prior to etching, scattering spectra of oxidized samples had been measured and the results were compared. Oxide films grown under various conditions on low carbon steel CSN 41 1373 were used in the experiment. The Moessbauer absorption spectrum measurement was found to be useful in the quantitative determination of phase composition. (L.O.)

Alternative Center of emergency Management; Centro alternativo de gestion de la emergencia

Energy Technology Data Exchange (ETDEWEB)

Turrion Lopez, F.

2013-07-01

Requirements and general considerations The alternative Center for emergency management (CAGE) is the project engineering and construction that have operating NPPS Spanish in December 2015. It will allow to support the Organization of response to Emergencies, combining the continuity of mitigation actions of the accident with rest and protection of staff, accommodating such executions. Depending on the State of the plant and the evolution of the emergency. The CSN and UNESA have been progressively defined the detailed criteria that has of design CAGE.

Contribution to the improvement of radon risk evaluation in Spain

International Nuclear Information System (INIS)

Ortega, X.; Vargas, A.

2002-01-01

The 96/29/Euratom Directive aims to introduce radon regulation at working places in European Countries. Within the framework, the Spanish Nuclear Regulatory Body, the Nuclear Safety Council (CSN), is interested in obtaining a reliable level of quality for radon measurements in Spain. The radon laboratory group at the Institute of Energetic Techniques of the Technical University of Catalonia in Barcelona (INTE) has been commissioned to adequate its radon chamber for testing radon instruments using standards as IEC 61577 and ISO 13466

Radioactively contaminated metallic materials: the search for a global solution; Materiales metalicos con contaminacion radiactiva: en busca de una solucion global

Energy Technology Data Exchange (ETDEWEB)

Sanz, S.

2009-07-01

Radioactively contaminated metallic materials: the search for a global solution. Tarragona hosted the first International Conference on Control and Management of Inadvertent Radioactive Material in Metal Scrap, which was sponsored by the IAEA and organised by various Spanish entities, among them the CSN. The meeting served for the exchange of ideas and precautionary measures, a field in which Spain already has a long and recognised experience, and focussed on the voluntary Protocol, endorsed by the majority of the Spanish steelyards. (Author)

A quarter of a century of function assignment agreements with the autonomous communities. The

International Nuclear Information System (INIS)

Montero Sanchez, M. A.; Rodriguez Marti, M.; Urbano Pollato, I.; Zamora Martin, F.

2010-01-01

The CSN has the power to commission certain radioactive facility surveillance and inspection functions to the autonomous communities through an agreement between the Council and the regional government in question. The first of these agreements was signed in 1985 with the Regional Government of Catalonia, and during the 25 years that have passed since then similar agreements have been signed with eight other communities: Asturias, the Balearic Islands, the Canary Islands, Galicia, Murcia, Navarra, the Basque Country and the Community of Valencia. (Author)

Atividade antioxidante de três espécies de Eugenia (Myrtaceae)

OpenAIRE

Magina, Michele A.; Gilioli, Andressa; Moresco, Henrique H.; Colla, Guilherme; Pizzolatti, Moacir Geraldo; Brighente, Inês Maria Costa

2010-01-01

A atividade antioxidante dos extratos vegetais de Eugenia brasiliensis, E. beaurepaireana e E. umbelliflora foi avaliada usando diferentes métodos: Determinação da ação sequestrante de radicais livres usando DPPH, determinação do potencial redutor e determinação do potencial inibidor da peroxidação lipídica. Foi correlacionado também a o conteúdo de fenólicos totais e de flavonóides contidos nestes extratos e frações com a atividade antioxidante. As espécies E. brasiliensis e E. beaurepairean...

Experimentos de química recreativa con sulfato de cobre pentahidratado

Directory of Open Access Journals (Sweden)

Santiago Heredia-Avalos

2006-01-01

Full Text Available En este trabajo se proponen varias experiencias sencillas usando sales de sulfato de cobre pentahidratado. Todas ellas pueden realizarse en casa con utensilios de cocina y usando sustancias baratas, la mayoría de las cuales pueden encontrarse en un supermercado. Las experiencias propuestas permiten estudiar el proceso de cristalización del sulfato de cobre pentahidratado, reacciones de oxidación-reducción, de formación de precipitados e, incluso, reacciones de formación de complejos. Estas experiencias pretenden despertar el interés de los alumnos por la química.

Um esquema de autorização para a segurança em sistemas distribuídos de larga escala

OpenAIRE

Westphall, Carla Merkle

2013-01-01

Tese (doutorado) - Universidade Federal de Santa Catarina, Florianópolis, 2000. A especificação e o gerenciamento de políticas de autorização em sistemas que usam objetos distribuídos de larga escala representa um desafio para o estabelecimento de ambientes seguros. Esta tese propõe um Esquema de Autorização para sistemas distribuídos usando abstrações do modelo CORBA de segurança integrado aos suportes de segurança das plataformas Java e Web. Este esquema de autorização, construído usando...

Implementação de um sistema SIP para o sistema operacional Linux

OpenAIRE

Davison Gonzaga da Silva

2003-01-01

Resumo: Este trabalho apresenta a implementação de um Sistema de VoIP usando o Protocolo SIP. Este Sistema SIP foi desenvolvido para o Linux, usando-se a linguagem C++ em conjunto com a biblioteca QT. O Sistema SIP é composto de três entidades básicas: o Terminal SIP, o Proxy e o Servidor de Registros. O Terminal SIP é a entidade responsável por estabelecer sessões SIP com outros Terminais SIP. Para o Terminal SIP, foi desenvolvida uma biblioteca de acesso à placa de áudio, que permite a modi...

Cultivo del pargo de la mancha Lutjanus guttatus (pisces: Lutjanidae en jaulas flotantes.

Directory of Open Access Journals (Sweden)

Ricardo Gutiérrez Vargas

2016-03-01

Full Text Available En dos ensayos paralelos realizados frente a Playa Pájaros, en el Golfo de Nicoya, se engordaron pargos manchados (Lutjanus guttatus obtenidos del medio hasta 275 y 485 g, respectivamente, usando fauna de descarte obtenida de barcos camaroneros. La tasa de crecimiento fue de 1,87 y 1,7 g/día, respectivamente, el factor de conversión fue de 7,88 (alimento húmedo o 1,77 (alimento seco. La mortalidad se estimó en un 6% en todo el experimento. Se calcularon los costos de alimentación usando la fauna de descarte.

Una nueva lectura de los niveles de Kohlberg, a través de la metodología DBM

OpenAIRE

Iriarte, Martha; Martí Vilar, Manuel

2012-01-01

Resumen: Utilizando algunos modelos de la metodología DBM (Developmental Behavioral Modelling) se hace una nueva lectura de las etapas del desarrollo del juicio moral de L. Kohlberg. Este autor sigue siendo un referente en la psicología moral en la actualidad, como lo demuestra su citación en el Social Science Citation Index y en los estudios bibliométricos realizados. Se presenta la distinción entre ¿qué¿ hace una persona al realizar un juicio moral y ¿cómo¿ lo hace. Se introduce el modelo D...

Campimetría usando realidad virtual

Directory of Open Access Journals (Sweden)

Juan Posada

2001-04-01

Full Text Available

La campimetría es de gran utilidad en el diagnóstico y seguimiento
de enfermedades retinianas y ha evolucionado de los métodos
manuales a las modernas técnicas automatizadas. Los objetivos principales son: diseñar, desarrollar y validar un programa en realidad virtural (RV para la realización de campimetrías, desarrollar una página WEB para presentación de avances del proyecto y crear una línea de investigación para el desarrollo de otras aplicaciones médicas con RV.

Sistema agropecuario integrado usando labranza cero

OpenAIRE

Pedro Paneque Rondón

2003-01-01

En el trabajo se muestra una tecnología de punta con vistas a desarrollar la explotación de las actividades agrícolas y pecuarias en una misma finca, para la producción de granos, cahe y leche, simultáneamente de forma programada, aplicando la tecnología denominada "Integración Agricultura-Pecuaria", con el propósito de obtener mejor apro v echamiento de los bienes de producción, mano de obra, maquinaria, instalaciones y principalmente el suelo

Criptografia usando curvas hiperelípticas

Directory of Open Access Journals (Sweden)

Alonso Sepúlveda Castellanos

2006-01-01

Full Text Available In this work we present some properties of the hyperelliptical curves and their Jacobians, aiming at the implementation of criptossystems of public key. Also we show the algorithm of Cantor to add points in the Jacobian manifold, which is important for the effectiveness of criptossystems, and an algorithm to attack the problem of the discrete logarithms on these groups. The untractability of this problem is essential for the security of criptossystems.

Produccion de plantas grandes usando minicontenedores

Science.gov (United States)

R. Kasten Dumroese; Thomas D. Landis

2012-01-01

En América del Norte hay cada vez más interés por la producción híbrida o mixta. La misma consiste en cultivar plantines en contenedores de pequeño volumen y luego trasplantarlos; el trasplante se puede realizar a canteros en el suelo como en la producción a raíz desnuda o bien a contenedores más grandes. Originalmente se llamaban plantines "plug+", "...

"Y el resto se hace con gritos": Notas sobre literatura y teatro

Directory of Open Access Journals (Sweden)

Marcela Arpes

2009-07-01

Full Text Available Quisiera comenzar con un, más o menos extenso, listado de obras de teatro que aún permanecen en cartel o, en todo caso, algunas de ellas lo estuvieron hasta marzo, en salas oficiales y alternativas del circuito teatral porteño pero, también, del interior del país: Tres para el té sobre textos de Lewis Carroll; Galileo, sobre la mesa sobre el texto de Bertolt Brecht; Federico tuvo un sueño, inspirada en el cuento de Antonio Tabucchi y en textos poéticos de Federico García Lorca; Los siete locos, de Roberto Arlt; Crave de Sarah Kane; Cielo rojo, el sueño Bolchevique del poeta Vladimir Maiacovsky; La Manchada, sobre Cuentos de la selva de Horacio Quiroga; Doña Flor y sus dos maridos de Jorge Amado; Grande y Pequeño del escritor alemán contemporáneo Botho Strauss; El diario de Anna Frank; Esa que no eres sobre textos de Alejandra Pizarnik, obra que recibió este verano el premio Estrella de Mar en la categoría mejor espectáculo del teatro off; La revolución silenciada sobre la obra Tres jueces para un largo silencio de Andrés Lizarraga, aquel escritor y dramaturgo argentino, el primero en recibir el premio Casas de las Américas; El mundo ha vivido equivocado de Roberto Fontanarrosa; Una vida más cuerda mañana, sobre textos de Griselda Gambaro, Sarah Kane y Vicente Zito Lema; La Divina Comedia de Dante Alighieri: Mi madre Mi Tierra donde conviven textos literarios de autores como Gloria Fuertes y Federico García Lorca; Sabor a Freud de José Pablo Feinman; El Corazón Delator de Edgar Allan Poe; El Relato de Lady Sotheby. de Marlene Spindler, espectáculo basado en textos de Fiodor Dostoyevsky y Stefan Zweig; Juicio al tango, sobre textos de Leopoldo Marechal; El día que Nietzsche lloró, título de la primera novela del profesor de psiquiatría de la Universidad de Stanford, Irvin Yalom; El último encuentro de Sándor Márai, versión escénica de la exitosa novela “El último encuentro” de Sándor Márai aquel escritor best-seller, antifascista, húngaro que fuera consagrado en el mundo entero luego de su trágico suicidio; El diario privado de Adán y Eva de Mark Twain; La Última Cena, sobre la novela de Dan Rosen; Fausto de Goethe; Una sociedad secreta, inspirada en el mundo poético de Roberto Arlt y Armando Discépolo. Además de los clásicos dramatúrgicos como Miller, Shakespeare, Chejov, Moliere, O’Neill, Pavlovsky, Gambaro, Beckett, Pinter, Sófocles y la enumeración sigue.

Hoy hace: 13 años del Terremoto de Limón

Directory of Open Access Journals (Sweden)

Vallejos Vásquez, Sheily

2005-08-01

Full Text Available Se presenta una compilación de información referente al terremoto de Limón, ocurrido el día 22 de abril de 1991. Presenta algunos de los principales datos técnicos y de afectación. También explica los efectos producidos a nivel geológico y las acciones prioritarias que se realizaron. Por último, se expone la importancia que tuvo el sismo para la Comisión Nacional de Prevención de Riesgos y Atención de Emergencias y para la ejecución de iniciativas en la organización del país en el tema de los desastres It presents a compilation of the information in regards to the Limon earthquake, April 22, 1991. It presents some of the main technical and affectation data. It also explains the geological effects and the main actions taken. Lastly, it exposes the importance that the earthquake had for the National Commission of Risk Prevention and Emergency Response and for the execution of initiatives in the country organization in the topic of disasters

"Y el resto se hace con gritos": Notas sobre literatura y teatro

Directory of Open Access Journals (Sweden)

Marcela Arpes

2009-06-01

Full Text Available Quisiera comenzar con un, más o menos extenso, listado de obras de teatro que aún permanecen en cartel o, en todo caso, algunas de ellas lo estuvieron hasta marzo, en salas oficiales y alternativas del circuito teatral porteño pero, también, del interior del país: Tres para el té sobre textos de Lewis Carroll; Galileo, sobre la mesa sobre el texto de Bertolt Brecht; Federico tuvo un sueño, inspirada en el cuento de Antonio Tabucchi y en textos poéticos de Federico García Lorca; Los siete locos, de Roberto Arlt; Crave de Sarah Kane; Cielo rojo, el sueño Bolchevique del poeta Vladimir Maiacovsky; La Manchada, sobre Cuentos de la selva de Horacio Quiroga; Doña Flor y sus dos maridos de Jorge Amado; Grande y Pequeño del escritor alemán contemporáneo Botho Strauss; El diario de Anna Frank; Esa que no eres sobre textos de Alejandra Pizarnik, obra que recibió este verano el premio Estrella de Mar en la categoría mejor espectáculo del teatro off; La revolución silenciada sobre la obra Tres jueces para un largo silencio de Andrés Lizarraga, aquel escritor y dramaturgo argentino, el primero en recibir el premio Casas de las Américas; El mundo ha vivido equivocado de Roberto Fontanarrosa; Una vida más cuerda mañana, sobre textos de Griselda Gambaro, Sarah Kane y Vicente Zito Lema; La Divina Comedia de Dante Alighieri: Mi madre Mi Tierra donde conviven textos literarios de autores como Gloria Fuertes y Federico García Lorca; Sabor a Freud de José Pablo Feinman; El Corazón Delator de Edgar Allan Poe; El Relato de Lady Sotheby. de Marlene Spindler, espectáculo basado en textos de Fiodor Dostoyevsky y Stefan Zweig; Juicio al tango, sobre textos de Leopoldo Marechal; El día que Nietzsche lloró, título de la primera novela del profesor de psiquiatría de la Universidad de Stanford, Irvin Yalom; El último encuentro de Sándor Márai, versión escénica de la exitosa novela “El último encuentro” de Sándor Márai aquel escritor best-seller, antifascista, húngaro que fuera consagrado en el mundo entero luego de su trágico suicidio; El diario privado de Adán y Eva de Mark Twain; La Última Cena, sobre la novela de Dan Rosen; Fausto de Goethe; Una sociedad secreta, inspirada en el mundo poético de Roberto Arlt y Armando Discépolo. Además de los clásicos dramatúrgicos como Miller, Shakespeare, Chejov, Moliere, O’Neill, Pavlovsky, Gambaro, Beckett, Pinter, Sófocles y la enumeración sigue.

Teoría de Brill-Noether para haces vectoriales de rango mayor

OpenAIRE

Yee Romero, Carlos

2004-01-01

Un problema clásico en variable compleja fue determinar la existencia de funciones mero- morfas en C; que tienen puntos fijos como ceros y polos con multiplicidad determinada, así como describir el espacio que generan estas funciones.

Un buen artículo científico hace una revista prestigiosa

Directory of Open Access Journals (Sweden)

Saray Córdoba González

2009-06-01

Full Text Available En esta nota se ofrecen las razones por las cuales se deben elaborar artículos científicos construidos de acuerdo con las normas internacionales establecidas y los principios de rigurosidad y originalidad necesarios para que sean aprobados por los árbitros especialistas en el campo. Además, se desarrollan varias ideas relacionadas con la ética del escritor, destacando las buenas prácticas y aclarando lo que no debe hacerse. Se concluye que solo con buenos artículos, los profesionales e investigadores costarricenses pueden contribuir a mejorar los aportes científicos y profesionales que se puedan generar en el país. De igual manera, las revistas científicas costarricenses mejorarán su visibilidad y aportes a la ciencia mundial.

Experiments with radioactive nuclear beams II; Experimentos con haces nucleares radiactivos II

Energy Technology Data Exchange (ETDEWEB)

Aguilera R, E.F.; Martinez Q, E.; Gomez C, A.; Lizcano C, D.; Garcia M, H.; Rosales M, P. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

2001-12-15

The studies of nuclear reactions with heavy ions have been carried out for years for the group of heavy ions of the laboratory of the Accelerator of the ININ. Especially in the last years the group has intruded in the studies of nuclear reactions with radioactive beams, frontier theme at world level. Presently Technical Report is presented in detailed form the experimental methods and the analysis procedures of the research activities carried out by the group. The chpater II is dedicated to the procedures used in the analysis of the last two experiments with radioactive beams carried out by the group. In the chapter III is presented the procedure followed to carrying out an extended analysis with the CCDEF code, to consider the transfer channel of nucleons in the description of the fusion excitation functions of a good number of previously measured systems by the group. Finally, in the chapter IV the more important steps to continue in the study of the reaction {sup 12}C + {sup 12}C experiment drifted to be carried out using the available resources of the Tandem Accelerator Laboratory of the ININ are described. At the end of each chapter some of the more representative results obtained in the analysis are presented and emphasis on the scientific production generated by the group for each case is made. (Author)

Hoy hace: Sismo de Tilarán, 14 de abril de 1973

Directory of Open Access Journals (Sweden)

Esquivel Valverde, Lidier

2005-08-01

Full Text Available Como parte de un proyecto del Departamento de Prevención y Mitigación de la Comisión Nacional de Prevención de Riesgos y Atención de Emergencias, que busca mantener en la memoria de la población una serie de eventos históricos relacionados con emergencias, se presenta una reseña sobre el sismo de Tilarán el 14 de abril de 1973, donde se narran algunas de las situaciones que se dieron, entre ellos datos técnicos sobre el sismo y un recuento de los daños y pérdidas As part of one Project of the Prevention and Mitigation Department of the National Commission of Risk Prevention and Emergency Response that tries to maintain in the memory of the population a series of historical events related to emergencies, it is presented a summary of the Tilarán earthquake, April 14, 1973, which narrates some of the situations occurred, among them technical data about the earthquake and a summary of the damages and losses

El llano, la imagen y el femenino eterno en la poesía de Carranza

Directory of Open Access Journals (Sweden)

Benigno Acosta Polo

1962-02-01

Full Text Available Cuando saboreamos la poesía de Eduardo Carranza, en sus diversos avatares, advertimos que a lo largo de ella el Llano hace acto de presencia. Lo lleva en la sangre, en la pupila y el alma. Se hace esencia y presencia de su numen.

Lesão brônquica e pneumotórax após reintubação usando um cateter para troca da via aérea

Directory of Open Access Journals (Sweden)

Juliano P. de Almeida

2013-02-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: Relatamos um caso de pneumotórax causado por perfuração brônquica durante uma reintubação usando um cateter para troca da via aérea (CTVA em um paciente com câncer de cabeça e pescoço. RELATO DE CASO: Paciente do sexo masculino, 53 anos, com carcinoma de orofaringe, foi internado na UTI com pneumonia grave e síndrome da angústia respiratória aguda (SARA. O paciente foi identificado como sendo de difícil intubação e uma sonda endotraqueal (SET foi inserida através de um broncoscópio. Após uma semana de tratamento, observou-se ruptura do manguito endotraqueal. A troca da sonda endotraqueal foi necessária para obter uma ventilação pulmonar satisfatória. Um cateter para troca da via aérea (Cook, tamanho 14 foi usado para realizar a reintubação. Depois da reintubação, o paciente apresentou piora na saturação de oxigênio e uma radiografia revelou um grande pneumotórax. Um dreno torácico foi inserido e uma melhora imediata na saturação de oxigênio foi observada. A repetição da radiografia confirmou o posicionamento correto do dreno torácico e a reexpansão do pulmão direito. A broncoscopia realizada mostrou uma laceração posterior do brônquio principal direito. O paciente foi extubado no dia seguinte. Depois de quatro dias, o dreno torácico foi removido. A radiografia realizada um dia depois da retirada do dreno revelou um pequeno pneumotórax no lobo superior direito, mas o paciente permaneceu assintomático. CONCLUSÕES: O cateter para troca da via aérea é uma ferramenta valiosa para lidar com pacientes difíceis de intubar. Embora os médicos geralmente concentrem sua atenção em evitar um barotrauma causado pelo suplemento de oxigênio ou ventilação a jato através do CTVA, a preocupação com a técnica de inserção pode minimizar as complicações que ameaçam a vida e aumentar a segurança do CTVA.

Resultados Preliminares sobre Estudios de Evapotranspiración del Cacao.

Directory of Open Access Journals (Sweden)

Navarrete S. Cristóbal

1960-06-01

Full Text Available El objeto de este trabajo fue determinar los requerimientos de agua por el cacaotero. De los múltiples métodos que existen para este fin, solo el que hace uso de la evapotranspirometría da la solución deseada. El método se basa en que el agua del suelo establece un equilibrio entre el agua que entra, como resultado de la precipitación y el agua que sale a través de la evaporación y transpiración. Para este estudio se están usando cuatro evapotranspirómetros de 2 x 2 metros en la parte superior y 1.20 metros de profundidad: un quinto tanque sirve de fosa colectora, donde se tienen las canecas que recogen las aguas de drenajes. A los evapotranspirómetros se trasplantaron cacaoteros de tres y medio años de edad del Clon 6. Posteriormente fueron rellenados consuelo del mismo lugar y procedente de la excavación. La estación de evapotranspirometría se localizó en medio de una plantación comerciaal de cacao del clon 6 de la misma edad, en la que se ha demarcado una zona buffer de 50 x 50 mts., ésta se riega en la misma forma que los tanques evapotranspirómetros. A éstos se les aplica una cantidad medida de agua cuando no llueve en las 24 horas anteriores. La evapotranspiración potencial se mide restando del agua aplicarla la la cantidad recogida en las canecas, esto se hace para cada tanque todos los días a las 8 a.m. Además de la evapotranspiración potencial, diariamente se toman datos metereológicos en aparatos localizados junto a los tanques experimentales. La información para tres meses; indica que el agua de lluvia sólo suministró el 42.19% y el 63.33% de los requerimientos de agua para el cacaotero en los meses de febrero y marzo respectivamente. En el mes de abril la precipitación fue superior a los requerimientos de agua, va que el consumo fue de 58.46 mm. Y la precipitación de 129.5 mm. Debido a la información tan escasa (tres meses solamente aquí presentada, es imposible, por el momento

Identificación del agente causal de la antracnosis de Sansevieria spp. en Costa Rica

OpenAIRE

Pérez-León, Gerardo; Chavarría-Pérez, Lourdes; Araya-Quesada, Julio; Gómez-Alpízar, Luis

2013-01-01

Sansevieria spp. (Agavaceae) es una ornamental de follaje originaria de África y Asia. S. trifasciata (St) es la especie con mayor número de cultivares en el mercado de exportación de Costa Rica a Estados Unidos y Holanda. Muestras foliares de S. trifasciata var. “Hahnii” con lesiones circulares y acuosas (algunas alargadas y secas), fueron analizadas. El patógeno recuperado fue identificado como Colletotrichum sansevieriae Nakamura (CsN) mediante pruebas de patogenicidad, morfología y técnic...

Infrastructure to support trading strategies against the occurrence of extraordinary events: Secure area of the equipment storage

International Nuclear Information System (INIS)

Blas Gordo, A. de; Asensio Vega, J.; Fernandez Morales, E. J.; Font Hadinger, I.

2013-01-01

Compliance with the requirements specified in the Technical Instructions ITC and ITC-1-2, issued by the Nuclear Safety Council (CSN), is conducting exhaustive analyzes on coping in Nuclear Power Plants emergencies due to the occurrence extraordinary events. As part of the necessary infrastructure, a secure area for parking and storage of projects teams involved in the development of various operational strategies. The design of it ensures compliance with all regulatory and practical requirements, ensuring minimization strategies and time functionality in the application of the same.

Application of atomic absorption in molecular analysis (spectrophotometry)

International Nuclear Information System (INIS)

Baliza, S.V.; Soledade, L.E.B.

1981-01-01

The apparatus of atomic absorption has been considered by all the experts in chemical analysis as one of the most important equipments in actual utilization in such field. Among its several applications one should emphasize direct and indirect metals analyses using flame, graphite furnace, cold vapor generator,... Besides such known applications, the authors have developed at the R and D Center of CSN a patent pendent method for the utilization of such equipment for molecular analysis, in substitution of a sophisticated and specific apparatus. (Author) [pt

Svařování kovů a zkoušení svárů podle nových norem ISO, EN a na ně navazujících ČSN

OpenAIRE

HAJNÝ, Tomáš

2010-01-01

Work considers kind of materials joining via welding. At the begining the bachelor work considers history of this branch. Then there are norms and regulations ISO, EN and CSN for welding. Next part describes welding methods and weld tests. The last part is focused on common technology of welding. Ambition of this bachelor work is to create learning text and briefly show to the students, which are the methods and kinds of welding and welding tests and possibility how to use this methods in pra...

The converged Sn algorithm for nuclear criticality

International Nuclear Information System (INIS)

Ganapol, B. D.; Hadad, K.

2009-01-01

A new discrete ordinates algorithm to determine the multiplication factor of a 1D nuclear reactor, based on Bengt Carlson's S n method, is presented. The algorithm applies the Romberg and Wynn-epsilon accelerators to accelerate a 1D, one-group S n solution to its asymptotic limit. We demonstrate the feasibility of the Converged Sn (CSn) solution on several one-group criticality benchmark compilations. The new formulation is especially convenient since it enables highly accurate critical fluxes and eigenvalues using the most fundamental transport algorithm. (authors)

Usage of abrasion-resistant materials in agriculture

Directory of Open Access Journals (Sweden)

J Votava

2014-06-01

Full Text Available Agricultural soil-processing machines are subject to an extensive abrasive wear. This paper analyses technical materials and their fitness to exchangeable parts of plough bottoms, such as edge-tools and whole plough cutting edges. There were tested abrasion-resistant steels with different microstructures: austenite, martensite-bainite, and carbide. Steel with the pearlite-ferrite structure was used as an etalon. Abrasion resistance tests were processed in compliance with the norm CSN 01 5084, which is a test of abrasion wear on abrasive cloth.

Infrastructure to support trading strategies against the occurrence of extraordinary events: Secure area of the equipment storage; Infraestructura de apoyo a las estrategias de operacion frente a la ocurrencia de sucesos extraordinarios: Area segura de almacenamiento de equipos

Energy Technology Data Exchange (ETDEWEB)

Blas Gordo, A. de; Asensio Vega, J.; Fernandez Morales, E. J.; Font Hadinger, I.

2013-07-01

Compliance with the requirements specified in the Technical Instructions ITC and ITC-1-2, issued by the Nuclear Safety Council (CSN), is conducting exhaustive analyzes on coping in Nuclear Power Plants emergencies due to the occurrence extraordinary events. As part of the necessary infrastructure, a secure area for parking and storage of projects teams involved in the development of various operational strategies. The design of it ensures compliance with all regulatory and practical requirements, ensuring minimization strategies and time functionality in the application of the same.

New ICRU quantities for the environmental and individual monitoring. Standardization of individual dosemeters by using external beams of photon radiation; Nuevas magnitudes ICRU para la vigilancia radiologica ambiental e individual. Calibracion de dosimetros personales usando haces externos de fotones

Energy Technology Data Exchange (ETDEWEB)

Brosed, A; Delgado, A; Granados, C E

1987-07-01

The quantities introduced by ICRU for the radiological monitoring are commented, specially those implied in individual protection against external photons. A procedure is proposed in order to standardize the individual dosemeters by using the kerma in air references of CIEMAT-JEN. The reference radiation beams are described in connection with ISO standards. Provisional values are selected for the appropriate conversion and correction factors. (Author) 23 refs.

Genetic polymorphism of CSN1S2 in South African dairy goat ...

African Journals Online (AJOL)

Rulien

2016-12-24

Dec 24, 2016 ... variation for αs2-casein in the South African goat populations ... of Pretoria's experimental farm (Saanens) and commercial goat farms in the provinces of Gauteng. (Toggenburg), North West (British Alpine and Toggenburg), ...