WorldWideScience

Sample records for crosswalk signal design

  1. Safety effectiveness of pavement design treatment at intersections: Left turning vehicles and pedestrians on crosswalks

    Directory of Open Access Journals (Sweden)

    Hasina Iasmin

    2016-07-01

    Full Text Available Pedestrians are the most vulnerable road users as they are more exposed than other road users. Pedestrian safety at road intersections still remains the most vital and yet unsolved issue. One of the critical points in pedestrian safety is the occurrence of accidents between left-turning vehicle and pedestrians on crosswalks at signalized intersections. A crosswalk is a place designated for pedestrians and cyclists to cross vehicular roads safely. Drivers are expected to give priority to pedestrians or cyclists during interactions between them on the crosswalk. If a driver exhibits non-yielding behavior, the interaction will turn into a collision. This study examined the safety effect of three crosswalks designed with different materials such as red-colored material or brick pavement based on a safety performance study. The safety performance study considered left-turning driver's gap acceptance behavior and the severity of traffic conflict events between left-turning vehicles and pedestrians. The results of the study indicates that using brick pavement on a crosswalk increases the safety level of the crosswalk. Drivers at such crosswalks are more acquiescent to the priority rule.

  2. Analysis of Crossing Speed of the Pedestrians in Marked and Unmarked Crosswalks in the Signalized and Un-Signalized Intersections (Case Study: Rasht city)

    Science.gov (United States)

    Behbahani, Hamid; Najafi Moghaddam Gilani, Vahid; Jahangir Samet, Mehdi; Salehfard, Reza

    2017-10-01

    Pedestrians affect the traffic in the signalized and un-signalized intersections. Therefore, identifying the behavioural features of the pedestrians is of great importance and may result in better designing facilities for them. In this study, by shooting the four intersections in Rasht for 15 hours and inventory from 4568 pedestrians, crossing speed of the pedestrians in the marked crosswalks and unmarked crosswalks was evaluated and analysed. Results showed that pedestrians‧ crossing speed in the marked crosswalks is higher than their crossing speed in the unmarked crosswalks in both signalized and un-signalized intersections. Moreover, in the unmarked crosswalks in the signalized intersections, 15th percentile speed of male pedestrians, female pedestrians and group of pedestrians’ decrease 6.4%, 5.4% and 12.2%, respectively, compared with the 15th percentile speed in the marked crosswalks. Above-mentioned values in the unmarked crosswalks in the un-signalized intersections for male pedestrians, female pedestrians, and group of pedestrians decrease 1.2%, 3.8%, and 1.4%, respectively.

  3. Using Cellular Automata to Investigate Pedestrian Conflicts with Vehicles in Crosswalk at Signalized Intersection

    Directory of Open Access Journals (Sweden)

    Xiaomeng Li

    2012-01-01

    Full Text Available The operational efficiency and safety of pedestrian flows at intersections is an important aspect of urban traffic. Particularly, conflicts between pedestrians and vehicles in crosswalk are one of the most influential factors for intersection safety. This paper presents a cellular automata model that simulates pedestrian and vehicle crossing behaviors at signalized intersections. Through the simulation, we investigate the effects of different pedestrian signal timing and crosswalk widths on the crosswalk capacity, the number of traffic conflicts between pedestrians and vehicles, and pedestrian delay due to the conflicts. The simulation results indicate that the cellular automata is an effective simulation platform for investigating complex pedestrian-related traffic phenomenon at signalized intersections.

  4. Situational Factors of Influencing Drivers to Give Precedence to Jaywalking Pedestrians at Signalized Crosswalk

    Directory of Open Access Journals (Sweden)

    Xiaobei Jiang

    2011-12-01

    Full Text Available A large number of fatalities are caused by the vehicle-pedestrian accidents. Under a potential conflict between the vehicle and jaywalking pedestrian, giving precedence to the pedestrian will be a proper decision taken by the driver to avoid collision. Field traffic data has been collected by video recording and image processing at two signalized crosswalks. Vehicle speed performance in the single vehicle-pedestrian encounter and platoon vehicle-pedestrian encounter were analyzed for understanding the driver behavior in the conflict process. Binary logic model was proposed to estimate the drivers' giving precedence influenced by the situational factors and the model was validated to predict the drivers' choices accurately. The vehicle speed, pedestrian speed, pedestrian lateral distance and the vehicle longitudinal distance to the conflict point were proved to affect the drivers' choices in platoon driving. The research results would hopefully be helpful to the design of intelligent vehicles and pedestrian protection systems by the knowledge-based decision making process.

  5. Estimating Safety Effects of Green-Man Countdown Devices at Signalized Pedestrian Crosswalk Based on Cellular Automata

    Directory of Open Access Journals (Sweden)

    Chen Chai

    2017-01-01

    Full Text Available Safety effects of Green-Man Countdown Device (GMCD at signalized pedestrian crosswalks are evaluated. Pedestrian behavior at GMCD and non-GMCD crosswalks is observed and analyzed. A microsimulation model is developed based on field observations to estimate safety performance. Simulation outputs allow analysts to assess the impacts of GMCD at various conditions with different geometric layout, traffic and pedestrian volumes, and the green time. According to simulation results, it is found that the safety impact of GMCD is affected by traffic condition as well as different time duration within green-man signal phase. In general, GMCD increases average walking velocity, especially during the last few seconds. The installation of GMCD improves safety performance generally, especially at more crowded crossings. Conflict severity is increased during last 10 s after GMCD installation. Findings from this study suggest that the current practice, which is to install GMCD at more crowded crosswalks or near the school zone, is effective. Moreover, at crosswalks with GMCD, longer all red signal phase is suggested to improve pedestrian safety during intergreen period.

  6. Effects of Pedestrian Prompts on Motorist Yielding at Crosswalks

    Science.gov (United States)

    Crowley-Koch, Brian J.; Van Houten, Ron; Lim, Eunyoung

    2011-01-01

    Pedestrian safety is a serious concern at busy intersections and pedestrian campuses across the nation. Although crosswalks and signs inform pedestrians where to cross, there is no standard protocol for pedestrians to signal drivers that they wish to use the crosswalks, except to stand in or at the crosswalk. We examined the effects of two…

  7. Modeling the impact of pedestrian behavior diversity on traffic dynamics at a crosswalk with push button

    Science.gov (United States)

    Xie, Dong-Fan; Zhao, Xiao-Mei; Li, Xin-Gang; Zhu, Tai-Lang

    2016-01-01

    Crosswalk with push button is prevalent in lots of cities for the purpose of promoting the efficiency of the crosswalk, and thus the delays of both vehicles and pedestrians can be reduced. This strategy has been confirmed to be effective in several developed countries. However, it is a pity that application of push button is aborted in some cities in China. In this work, diverse behaviors of vehicles and pedestrians are analyzed and discussed. Then, a microscopic model is developed by incorporating the interaction between vehicles and pedestrians. Numerical simulations are performed to reveal the characteristics of traffic flow and the efficiency of the signal control strategy. Also, the impacts of risker proportion and button reaction time, as well as the impacts of various behaviors as mass behavior, the patience of pedestrian and push button habit are investigated. It is expected that the results will be helpful to the strategy design of a signalized crosswalk in such developing countries as China.

  8. Motorist actions at a crosswalk with an in-pavement flashing light system.

    Science.gov (United States)

    Karkee, Ganesh J; Nambisan, Shashi S; Pulugurtha, Srinivas S

    2010-12-01

    An in-pavement flashing light system is used at crosswalks to alert motorists and pedestrians of possible conflicts and to influence their behavior to enhance safety. The relative behaviors of the drivers and the pedestrians affect safety. An evaluation of motorist behavior at a pedestrian crosswalk with an in-pavement flashing light system is presented in this manuscript. Field observations provide the basis to evaluate motorist behavior at a crosswalk with an in-pavement flashing light system. Outcomes of pedestrian and motorists actions were observed to quantify measures of effectiveness (MOEs) such as yielding behavior of motorists, vehicle speeds, and yielding distance from the crosswalk. A before-and-after study design was used. The before condition was prior to the activation of the in-pavement flashing light system and the after condition was after the activation of the in-pavement flashing light system. The study was conducted on a relatively low-volume roadway located in the Henderson, Nevada. The significance of the differences in the MOEs between the 2 study periods was evaluated using statistical analysis tools such as a one-tailed test for proportions and the Welch-Satterthwaite t-test. The results show that the installation of the in-pavement flashing light system increased the yielding behavior of motorists significantly (P pavement flashing light system is seen to be effective to improve motorists' yielding behavior and the speeds of vehicles were also observed to decrease in the presence of pedestrians.

  9. Pedestrian hybrid beacon crosswalk system (PHB) or high-intensity activated crosswalk (HAWK).

    Science.gov (United States)

    2014-11-01

    The Pedestrian Hybrid Beacon Crosswalk (PHB) is a type of traffic control system, used to aid : pedestrians safely crossing the street and to regulate traffic flow. This study examines the : success of the first PHB installed in the state of Vermont....

  10. Algebraic Methods to Design Signals

    Science.gov (United States)

    2015-08-27

    to date on designing signals using algebraic and combinatorial methods. Mathematical tools from algebraic number theory, representation theory and... combinatorial objects in designing signals for communication purposes. Sequences and arrays with desirable autocorrelation properties have many...multiple access methods in mobile radio communication systems. We continue our mathematical framework based on group algebras, character theory

  11. Webcams, Crowdsourcing, and Enhanced Crosswalks: Developing a Novel Method to Analyze Active Transportation.

    Science.gov (United States)

    Hipp, J Aaron; Manteiga, Alicia; Burgess, Amanda; Stylianou, Abby; Pless, Robert

    2016-01-01

    Active transportation opportunities and infrastructure are an important component of a community's design, livability, and health. Features of the built environment influence active transportation, but objective study of the natural experiment effects of built environment improvements on active transportation is challenging. The purpose of this study was to develop and present a novel method of active transportation research using webcams and crowdsourcing, and to determine if crosswalk enhancement was associated with changes in active transportation rates, including across a variety of weather conditions. The 20,529 publicly available webcam images from two street intersections in Washington, DC, USA were used to examine the impact of an improved crosswalk on active transportation. A crowdsource, Amazon Mechanical Turk, annotated image data. Temperature data were collected from the National Oceanic and Atmospheric Administration, and precipitation data were annotated from images by trained research assistants. Summary analyses demonstrated slight, bi-directional differences in the percent of images with pedestrians and bicyclists captured before and after the enhancement of the crosswalks. Chi-square analyses revealed these changes were not significant. In general, pedestrian presence increased in images captured during moderate temperatures compared to images captured during hot or cold temperatures. Chi-square analyses indicated the crosswalk improvement may have encouraged walking and biking in uncomfortable outdoor conditions (P < 0.5). The methods employed provide an objective, cost-effective alternative to traditional means of examining the effects of built environment changes on active transportation. The use of webcams to collect active transportation data has applications for community policymakers, planners, and health professionals. Future research will work to validate this method in a variety of settings as well as across different built

  12. Webcams, crowdsourcing, and enhanced crosswalks: Developing a novel method to analyze active transportation

    Directory of Open Access Journals (Sweden)

    J. Aaron eHipp

    2016-05-01

    Full Text Available Introduction: Active transportation opportunities and infrastructure are an important component of a community’s design, livability, and health. Features of the built environment influence active transportation, but objective study of the natural experiment effects of built environment improvements on active transportation is challenging. The purpose of this study was to develop and present a novel method of active transportation research using webcams and crowdsourcing, and to determine if crosswalk enhancement was associated with changes in active transportation rates, including across a variety of weather conditions. Methods: 20,529 publicly available webcam images from two street intersections in Washington, D.C., were used to examine the impact of an improved crosswalk on active transportation. A crowdsource, Amazon Mechanical Turk, annotated image data. Temperature data was collected from the National Oceanic and Atmospheric Administration, and precipitation data was annotated from images by trained research assistants. Results: Summary analyses demonstrated slight, bi-directional differences in the percent of images with pedestrians and bicyclists captured before and after the enhancement of the crosswalks. Chi-square analyses revealed these changes were not significant. In general, pedestrian presence increased in images captured during moderate temperatures compared to images captured during hot or cold temperatures. Chi-square analyses indicated the crosswalk improvement may have encouraged walking and biking in uncomfortable outdoor conditions (p<0.5. Conclusion: The methods employed provide an objective, cost-effective alternative to traditional means of examining the effects of built environment changes on active transportation. The use of webcams to collect active transportation data has applications for community policymakers, planners, and health professionals. Future research will work to validate this method in a variety of

  13. Small signal microwave amplifier design

    CERN Document Server

    Grosch, Theodore

    2000-01-01

    This book explains techniques and examples for designing stable amplifiers for high-frequency applications in which the signal is small and the amplifier circuit is linear. An in-depth discussion of linear network theory provides the foundation needed to develop actual designs. Examples throughout the book will show you how to apply the knowledge gained in each chapter leading to the complex design of low noise amplifiers. Many exercises at the end of each chapter will help students to practice their skills. The solutions to these design problems are available in an accompanying solutions book

  14. Crosswalk navigation for people with visual impairments on a wearable device

    Science.gov (United States)

    Cheng, Ruiqi; Wang, Kaiwei; Yang, Kailun; Long, Ningbo; Hu, Weijian; Chen, Hao; Bai, Jian; Liu, Dong

    2017-09-01

    Detecting and reminding of crosswalks at urban intersections is one of the most important demands for people with visual impairments. A real-time crosswalk detection algorithm, adaptive extraction and consistency analysis (AECA), is proposed. Compared with existing algorithms, which detect crosswalks in ideal scenarios, the AECA algorithm performs better in challenging scenarios, such as crosswalks at far distances, low-contrast crosswalks, pedestrian occlusion, various illuminances, and the limited resources of portable PCs. Bright stripes of crosswalks are extracted by adaptive thresholding, and are gathered to form crosswalks by consistency analysis. On the testing dataset, the proposed algorithm achieves a precision of 84.6% and a recall of 60.1%, which are higher than the bipolarity-based algorithm. The position and orientation of crosswalks are conveyed to users by voice prompts so as to align themselves with crosswalks and walk along crosswalks. The field tests carried out in various practical scenarios prove the effectiveness and reliability of the proposed navigation approach.

  15. Electrical deicing utilizing carbon fiber tape for asphalt approach and crosswalk phase I - literature review.

    Science.gov (United States)

    2016-06-30

    The purpose of this study is to provide a comprehensive literature review of electrical deicing technology for possible application in asphalt approach and crosswalks. A : thorough review of existing and emerging deicing technology for snow/ice melti...

  16. Racial Bias in Drivers' Yielding Behavior at Crosswalks : Understanding the Effect

    Science.gov (United States)

    2017-10-01

    This project explores social identity factors (race and gender) that influence drivers' behavior in interactions with pedestrians at crosswalks. One dangerous potential point of conflict for pedestrians within the transportation system is interaction...

  17. Signal conditioning circuitry design for instrumentation systems.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Cory A.

    2012-01-01

    This report details the current progress in the design, implementation, and validation of the signal conditioning circuitry used in a measurement instrumentation system. The purpose of this text is to document the current progress of a particular design in signal conditioning circuitry in an instrumentation system. The input of the signal conditioning circuitry comes from a piezoresistive transducer and the output will be fed to a 250 ksps, 12-bit analog-to-digital converter (ADC) with an input range of 0-5 V. It is assumed that the maximum differential voltage amplitude input from the sensor is 20 mV with an unknown, but presumably high, sensor bandwidth. This text focuses on a specific design; however, the theory is presented in such a way that this text can be used as a basis for future designs.

  18. White light signal simulator microcontroller design | Haghighi ...

    African Journals Online (AJOL)

    In this research, first through experimental studies, the recorded signals associated with the light white from human retina cells were digitized, then the digital data were calculated and the resulted mathematical equation was programmed on a microcontroller, and by designing a circuit, the output voltage over time similar to ...

  19. Crosswalking near-Earth and space physics ontologies in SPASE and ESPAS

    Science.gov (United States)

    Galkin, I. A.; Fung, S. F.; Benson, R. F.; Heynderickx, D.; Ritschel, B.; King, T. A.; Roberts, D. A.; Hapgood, M. A.; Belehaki, A.

    2015-12-01

    In order to support scientific discoveries in Heliophysics (HP), with modern data systems, the HP Data Centers actively pursue harmonization of available metadata that allows crossing boundaries between existing data models, conventions, and resource interfaces. The discoverability of HP observations is improved when associated metadata describes their physical content in agreed terms as a part of the resource registration. One of the great challenges of enabling such content-targeted data search capability is the harmonization of domain ontology across data providers. Ontologies are the cornerstones of the content-aware data systems: they define an agreed vocabulary of keywords that capture the essence of domain-specific concepts and their relationships. With the introduction of the Virtual Wave Observatory (VWO), as part of NASA's Virtual System Observatory in 2008, the task of formulating the HP ontology became yet more complicated. Definitions of the wave domain concepts required several layers of specifications that described the generation, propagation, and interaction of the waves with the underlying medium in addition to the observation itself. Simple keyword lists could not provide a sufficiently information-rich description, given the complexity of the wave domain, and the development of a more powerful schema was required. The ontology research at the VWO eventually resulted in a suitable multi-hierarchical design that found its first implementation in 2015 at one of the European space physics data repositories, the near-Earth Space Data Infrastructure for e-Science (ESPAS). Similar to many other European geoscience projects, ESPAS is based on the ISO 19156 Observation and Measurements standard. In cooperation with the NASA VWO, the ESPAS project has deployed a space physics ontology design for all data registration purposes. The VWO science team is now uniquely positioned to establish a crosswalk between the ESPAS ontology based on ISO 19156 and the VWO

  20. Real-time Multiresolution Crosswalk Detection with Walk Light Recognition for the Blind

    Directory of Open Access Journals (Sweden)

    ROMIC, K.

    2018-02-01

    Full Text Available Real-time image processing and object detection techniques have a great potential to be applied in digital assistive tools for the blind and visually impaired persons. In this paper, algorithm for crosswalk detection and walk light recognition is proposed with the main aim to help blind person when crossing the road. The proposed algorithm is optimized to work in real-time on portable devices using standard cameras. Images captured by camera are processed while person is moving and decision about detected crosswalk is provided as an output along with the information about walk light if one is present. Crosswalk detection method is based on multiresolution morphological image processing, while the walk light recognition is performed by proposed 6-stage algorithm. The main contributions of this paper are accurate crosswalk detection with small processing time due to multiresolution processing and the recognition of the walk lights covering only small amount of pixels in image. The experiment is conducted using images from video sequences captured in realistic situations on crossings. The results show 98.3% correct crosswalk detections and 89.5% correct walk lights recognition with average processing speed of about 16 frames per second.

  1. Effects of transverse rumble strips on safety of pedestrian crosswalks on rural roads in China.

    Science.gov (United States)

    Liu, Pan; Huang, Jia; Wang, Wei; Xu, Chengcheng

    2011-11-01

    The primary objective of this study is to evaluate the impacts of transverse rumble strips in reducing crashes and vehicle speeds at pedestrian crosswalks on rural roads in China. Using crash data reported at 366 sites, the research team conducted an observational before-after study using a comparison group and the Empirical Bayesian (EB) method to evaluate the effectiveness of transverse rumble strips in reducing crashes at pedestrian crosswalks. It was found that transverse rumble strips may reduce expected crash frequency at pedestrian crosswalks by 25%. The research team collected more than 15,000 speed observations at 12 sites. The speed data analysis results show that transverse rumble strips significantly reduce vehicle speeds in vicinity of pedestrian crosswalks on rural roads with posted speed limits of 60 km/h and 80 km/h. On average, the mean speed at pedestrian crosswalks declined 9.2 km/h on roads with a speed limit of 60 km/h; and 11.9 km/h on roads with a speed limit of 80 km/h. The 85th percentile speed declined 9.1 km/h on roads with a speed limit of 60 km/h; and 12.0 km/h on roads with a speed limit of 80 km/h. However, the speed reduction impacts were not found to be statistically significant for the pedestrian crosswalk on the road with a speed limit of 40 km/h. The study also looked extensively at the influence area of transverse rumble strips on rural roads. Speed profiles developed in this study show that the influence area of transverse rumble strips is generally less than 0.3 km. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Quantitative analysis of pedestrian safety at uncontrolled multi-lane mid-block crosswalks in China.

    Science.gov (United States)

    Zhang, Cunbao; Zhou, Bin; Chen, Guojun; Chen, Feng

    2017-11-01

    A lot of pedestrian-vehicle crashes at mid-block crosswalks severely threaten pedestrian's safety around the world. The situations are even worse in China due to low yielding rate of vehicles at crosswalks. In order to quantitatively analyze pedestrian's safety at multi-lane mid-block crosswalks, the number of pedestrian-vehicle conflicts was utilized to evaluate pedestrian's accident risk. Five mid-block crosswalks (Wuhan, China) were videoed to collect data of traffic situation and pedestrian-vehicle conflicts, and the quantity and spatial distribution of pedestrian-vehicle conflicts at multi-lane mid-block crosswalk were analyzed according to lane-based post-encroachment time(LPET). Statistical results indicate that conflicts are mainly concentrated in lane3 and lane6. Percentage of conflict of each lane numbered from 1 to 6 respectively are 4.1%, 13.1%, 19.8%, 8.4%, 19.0%, 28.1%. Conflict rate under different crossing strategies are also counted. Moreover, an order probit (OP) model of pedestrian-vehicle conflict analysis (PVCA) was built to find out the contributions corresponding to those factors (such as traffic volume, vehicle speed, pedestrian crossing behavior, pedestrian refuge, etc.) to pedestrian-vehicle conflicts. The results show that: pedestrian refuge have positive effects on pedestrian safety; on the other hand, high vehicle speed, high traffic volume, rolling gap crossing pattern, and larger pedestrian platoon have negative effects on pedestrian safety. Based on our field observation and PVCA model, the number of conflicts will rise by 2% while the traffic volume increases 200 pcu/h; similarly, if the vehicle speed increases 5km/h, the number of conflicts will rise by 12% accordingly. The research results could be used to evaluate pedestrian safety at multi-lane mid-block crosswalks, and useful to improve pedestrian safety by means of pedestrian safety education, pedestrian refuge setting, vehicle speed limiting, and so on. Copyright © 2017

  3. Auditory signal design for automatic number plate recognition system

    NARCIS (Netherlands)

    Heydra, C.G.; Jansen, R.J.; Van Egmond, R.

    2014-01-01

    This paper focuses on the design of an auditory signal for the Automatic Number Plate Recognition system of Dutch national police. The auditory signal is designed to alert police officers of suspicious cars in their proximity, communicating priority level and location of the suspicious car and

  4. AnalogRF and mixed-signal circuit systematic design

    CERN Document Server

    Tlelo-Cuautle, Esteban; Castro-Lopez, Rafael

    2013-01-01

    Despite the fact that in the digital domain, designers can take full benefits of IPs and design automation tools to synthesize and design very complex systems, the analog designers’ task is still considered as a ‘handcraft’, cumbersome and very time consuming process. Thus, tremendous efforts are being deployed  to develop new design methodologies in the analog/RF and mixed-signal domains. This book collects 16 state-of-the-art contributions devoted to the topic of systematic design of analog, RF and mixed signal circuits. Divided in the two parts Methodologies and Techniques recent theories, synthesis techniques and design methodologies, as well as new sizing approaches in the field of robust analog and mixed signal design automation are presented for researchers and R/D engineers.  

  5. Taking a Step Forward in Public Health Finance: Establishing Standards for a Uniform Chart of Accounts Crosswalk.

    Science.gov (United States)

    Honoré, Peggy A; Leider, Jonathon P; Singletary, Vivian; Ross, David A

    2015-01-01

    In its 2012 report on the current and future states of public health finance, the Institute of Medicine noted, with concern, the relative lack of capacity for practitioners and researchers alike to make comparisons between health department expenditures across the country. This is due in part to different accounting systems, service portfolios, and state- or agency-specific reporting requirements. The Institute of Medicine called for a uniform chart of accounts, perhaps building on existing efforts such as the Public Health Uniform National Data Systems (PHUND$). Shortly thereafter, a group was convened to work with public health practitioners and researchers to develop a uniform chart of accounts crosswalk. A year-long process was undertaken to create the crosswalk. This commentary discusses that process, challenges encountered along the way and provides a draft crosswalk in line with the Foundational Public Health Services model that, if used by health departments, could allow for meaningful comparisons between agencies.

  6. Analysis of Design of Mixed-Signal Electronic Packaging

    National Research Council Canada - National Science Library

    Pileggi, Lawrence

    1999-01-01

    The objective of this project is to develop innovative algorithms and prototype tools that will help facilitate the design of mixed signal multi-chip modules and packaging in a manner that is similar...

  7. The design of traffic signal coordinated control

    Science.gov (United States)

    Guo, Xueting; Sun, Hongsheng; Wang, Xifu

    2017-05-01

    Traffic as the tertiary industry is an important pillar industry to support the normal development of the economy. But now China's road traffic development and economic development has shown a great imbalance and fault phenomenon, which greatly inhibited the normal development of China's economy. Now in many large and medium-sized cities in China are implementing green belt construction. The so-called green band is when the road conditions to meet the conditions for the establishment of the green band, the sections of the intersection of several planning to a traffic coordination control system, so that when the driver at a specific speed can be achieved without stopping the continuous Through the intersection. Green belt can effectively reduce the delay and queuing length of vehicle driving, the normal function of urban roads and reduce the economic losses caused by traffic congestion is a great help. In this paper, the theoretical basis of the design of the coordinated control system is described. Secondly, the green time offset is calculated by the analytic method and the green band is established. And then the VISSIM software is used to simulate the traffic system before and after the improvement. Finally, the results of the two simulations are compared.

  8. Design, Modelling, and Implementation of a Fuzzy Controller for an Intelligent Road Signaling System

    Directory of Open Access Journals (Sweden)

    José Manuel Lozano Domínguez

    2018-01-01

    Full Text Available Crossing points are not always 100% visible for drivers due to different factors (e.g., poor road maintenance, occlusion of vertical signs, and adverse weather conditions. USA estimated in 2015 the number of traffic accidents involving pedestrians and vehicles in 70,000 of whom 5,376 resulted in deceased people. To contribute in this field, this paper presents the design, implementation, and testing of a smart prototype system applied to pedestrian crossings—not regulated by semaphores—which try to reduce the accident rate on roads. The hardware and software system consists of a set of autonomous, intelligent, and wireless low-cost devices that generate a visual warning barrier perceived by drivers from a suitable distance when pedestrians traverse a crosswalk. In this way, drivers can reduce the speed of their vehicles and stop safely. The system’s intelligence is carried out by a fuzzy controller that performs sensory fusion at both low level and high level with various types of sensors from local and neighboring devices. The tests conducted have determined an average success of 94.64% and a precision of 100%, thus corresponding with a very good test according to a ROC analysis. As a result, the system proposed has been patented and extended to international PCT.

  9. Foundations of digital signal processing theory, algorithms and hardware design

    CERN Document Server

    Gaydecki, Patrick

    2005-01-01

    An excellent introductory text, this book covers the basic theoretical, algorithmic and real-time aspects of digital signal processing (DSP). Detailed information is provided on off-line, real-time and DSP programming and the reader is effortlessly guided through advanced topics such as DSP hardware design, FIR and IIR filter design and difference equation manipulation.

  10. Analog integrated circuits design for processing physiological signals.

    Science.gov (United States)

    Li, Yan; Poon, Carmen C Y; Zhang, Yuan-Ting

    2010-01-01

    Analog integrated circuits (ICs) designed for processing physiological signals are important building blocks of wearable and implantable medical devices used for health monitoring or restoring lost body functions. Due to the nature of physiological signals and the corresponding application scenarios, the ICs designed for these applications should have low power consumption, low cutoff frequency, and low input-referred noise. In this paper, techniques for designing the analog front-end circuits with these three characteristics will be reviewed, including subthreshold circuits, bulk-driven MOSFETs, floating gate MOSFETs, and log-domain circuits to reduce power consumption; methods for designing fully integrated low cutoff frequency circuits; as well as chopper stabilization (CHS) and other techniques that can be used to achieve a high signal-to-noise performance. Novel applications using these techniques will also be discussed.

  11. Development of knowledgebase system for assisting signal validation scheme design

    International Nuclear Information System (INIS)

    Kitamura, M.; Baba, T.; Washio, T.; Sugiyama, K.

    1987-01-01

    The purpose of this study is to develop a knowledgebase system to be used as a tool for designing signal validation schemes. The outputs from the signal validation scheme can be used as; (1) auxiliary signals for detecting sensor failures, (2) inputs to advanced instrumentation such as disturbance analysis and diagnosis system or safety parameter display system, and (3) inputs to digital control systems. Conventional signal validation techniques such as comparison of redundant sensors, limit checking, and calibration tests have been employed in nuclear power plants. However, these techniques have serious drawbacks, e.g. needs for extra sensors, vulnerability to common mode failures, limited applicability to continuous monitoring, etc. To alleviate these difficulties, a new signal validation technique has been developed by using the methods called analytic redundancy and parity space. Although the new technique has been proved feasible as far as preliminary tests are concerned, further developments should be made in order to enhance its practical applicability

  12. The mathematical theory of signal processing and compression-designs

    Science.gov (United States)

    Feria, Erlan H.

    2006-05-01

    The mathematical theory of signal processing, named processor coding, will be shown to inherently arise as the computational time dual of Shannon's mathematical theory of communication which is also known as source coding. Source coding is concerned with signal source memory space compression while processor coding deals with signal processor computational time compression. Their combination is named compression-designs and referred as Conde in short. A compelling and pedagogically appealing diagram will be discussed highlighting Conde's remarkable successful application to real-world knowledge-aided (KA) airborne moving target indicator (AMTI) radar.

  13. Raised crosswalks on entrance to the roundabout-a case study on effectiveness of treatment on pedestrian safety and convenience.

    Science.gov (United States)

    Candappa, Nimmi; Stephan, Karen; Fotheringham, Nicola; Lenné, Michael G; Corben, Bruce

    2014-01-01

    A common concern in the use of a roundabout is providing adequately for the pedestrian. This unique roundabout layout, which introduces raised crosswalks directly at the roundabout entrance, as opposed to at a car length back, aims at improving safety and convenience for pedestrians at roundabouts. A preliminary evaluation of the layout was undertaken to establish its effectiveness in meeting study objectives. A quasi-experimental before-and-after study design was used to compare speeds on approach and immediately prior to the crossing to ascertain potential impact speed and implications for pedestrian safety. Compliance to crossing and crossing time were also compared in relation to safety and convenience outcomes. A questionnaire assessed pedestrian perception of the safety and convenience at the roundabout before and after treatment. Results from this case study indicate that mean approach speeds (free speeds 30 m from crossing) reduced from 32.7 to 30.7 km/h and immediately prior to crossing, mean speeds reduced from 19.1 to 16.3 km/h. There was also a marked reduction in proportions of vehicles traveling at speeds that could elevate risk to pedestrians. Total crossing time after treatment reduced by around 4 s, and crossing compliance increased from approximately half to approximately 90 percent. Survey of pedestrians indicated positive response to the perceived safety and convenience posttreatment. Preliminary results of the case study suggest positive safety and convenience outcomes. Implications for pedestrian safety include less exposure to traffic and lower risk of serious injury, particularly for elderly pedestrians; convenience outcomes include shorter waiting times to cross and greater compliance to the crossing. A larger study is required to substantiate the findings.

  14. Wireless receiver architectures and design antennas, RF, synthesizers, mixed signal, and digital signal processing

    CERN Document Server

    Rouphael, Tony J

    2014-01-01

    Wireless Receiver Architectures and Design presents the various designs and architectures of wireless receivers in the context of modern multi-mode and multi-standard devices. This one-stop reference and guide to designing low-cost low-power multi-mode, multi-standard receivers treats analog and digital signal processing simultaneously, with equal detail given to the chosen architecture and modulating waveform. It provides a complete understanding of the receiver's analog front end and the digital backend, and how each affects the other. The book explains the design process in great detail, s

  15. A Crosswalk of Mineral Commodity End Uses and North American Industry Classification System (NAICS) codes

    Science.gov (United States)

    Barry, James J.; Matos, Grecia R.; Menzie, W. David

    2015-09-14

    This crosswalk is based on the premise that there is a connection between the way mineral commodities are used and how this use is reflected in the economy. Raw mineral commodities are the basic materials from which goods, finished products, or intermediate materials are manufactured or made. Mineral commodities are vital to the development of the U.S. economy and they impact nearly every industrial segment of the economy, representing 12.2 percent of the U.S. gross domestic product (GDP) in 2010 (U.S. Bureau of Economic Analysis, 2014). In an effort to better understand the distribution of mineral commodities in the economy, the U.S. Geological Survey (USGS) attempts to link the end uses of mineral commodities to the corresponding North American Industry Classification System (NAICS) codes.

  16. Evaluating the effect of advance yield markings and symbolic signs on vehicle-pedestrian conflicts at marked midblock crosswalks across multilane roads.

    Science.gov (United States)

    2016-02-01

    The Commonwealth of Massachusetts has made walkable communities a priority. Pedestrian safety is key to the success of : this objective. Pedestrians are at high risk when traversing unsignalized, marked crosswalks located either midblock or at Tinter...

  17. Design principles of nuclear receptor signaling: how complex networking improves signal transduction

    Science.gov (United States)

    Kolodkin, Alexey N; Bruggeman, Frank J; Plant, Nick; Moné, Martijn J; Bakker, Barbara M; Campbell, Moray J; van Leeuwen, Johannes P T M; Carlberg, Carsten; Snoep, Jacky L; Westerhoff, Hans V

    2010-01-01

    The topology of nuclear receptor (NR) signaling is captured in a systems biological graphical notation. This enables us to identify a number of ‘design' aspects of the topology of these networks that might appear unnecessarily complex or even functionally paradoxical. In realistic kinetic models of increasing complexity, calculations show how these features correspond to potentially important design principles, e.g.: (i) cytosolic ‘nuclear' receptor may shuttle signal molecules to the nucleus, (ii) the active export of NRs may ensure that there is sufficient receptor protein to capture ligand at the cytoplasmic membrane, (iii) a three conveyor belts design dissipating GTP-free energy, greatly aids response, (iv) the active export of importins may prevent sequestration of NRs by importins in the nucleus and (v) the unspecific nature of the nuclear pore may ensure signal-flux robustness. In addition, the models developed are suitable for implementation in specific cases of NR-mediated signaling, to predict individual receptor functions and differential sensitivity toward physiological and pharmacological ligands. PMID:21179018

  18. Interpreting Quality of Life after Brain Injury Scores: Cross-Walk with the Short Form-36.

    Science.gov (United States)

    Wilson, Lindsay; Marsden-Loftus, Isaac; Koskinen, Sanna; Bakx, Wilbert; Bullinger, Monika; Formisano, Rita; Maas, Andrew; Neugebauer, Edmund; Powell, Jane; Sarajuuri, Jaana; Sasse, Nadine; von Steinbuechel, Nicole; von Wild, Klaus; Truelle, Jean-Luc

    2017-01-01

    The Quality of Life after Brain Injury (QOLIBRI) instruments are traumatic brain injury (TBI)-specific assessments of health-related quality of life (HRQoL), with established validity and reliability. The purpose of the study is to help improve the interpretability of the two QOLIBRI summary scores (the QOLIBRI Total score and the QOLBRI Overall Scale [OS] score). An analysis was conducted of 761 patients with TBI who took part in the QOLIBRI validation studies. A cross-walk between QOLIBRI scores and the SF-36 Mental Component Summary norm-based scoring system was performed using geometric mean regression analysis. The exercise supports a previous suggestion that QOLIBRI Total scores GOSE), as a measure of global function, are presented in the form of means and standard deviations that allow comparison with other studies, and data on age and sex are presented for the QOLIBRI-OS. While bearing in mind the potential imprecision of the comparison, the findings provide a framework for evaluating QOLIBRI summary scores in relation to generic HRQoL that improves their interpretability.

  19. Adding Archival Finding Aids to the Library Catalogue: Simple Crosswalk or Data Traffic Jam?

    Directory of Open Access Journals (Sweden)

    Geoff Brown

    2007-03-01

    Full Text Available Dalhousie University Archives and Special Collections (DUASC has been producing Encoded Archival Description (EAD finding aids to describe its archival collections since 2003. The EAD descriptions started as a way to convert the collection of print and electronic (Microsoft Word and WordPerfect finding aids into a stable, software neutral format. As the collection of finding aids grew, it became apparent that we needed a way to search these documents beyond what was possible via a basic browse on the DUASC website. As a result, we embarked on a systematic crosswalk of the EAD finding aids into MARC 21 format for inclusion in the Novanet library catalogue. This has facilitated searching and discovery of the materials by a much broader audience of Dalhousie University Library users as well as users from all of the other Novanet member libraries in Nova Scotia and the general public. This article describes the primary motivation for the project and the technical aspects of converting the EAD finding aids into MARC 21 format for inclusion in the Novanet catalogue.

  20. Modular Accident Analysis Program (MAAP) - MELCOR Crosswalk: Phase II Analyzing a Partially Recovered Accident Scenario

    Energy Technology Data Exchange (ETDEWEB)

    Andrews, Nathan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Faucett, Christopher [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Haskin, Troy Christopher [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Luxat, Dave [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Geiger, Garrett [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Codella, Brittany [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-10-01

    Following the conclusion of the first phase of the crosswalk analysis, one of the key unanswered questions was whether or not the deviations found would persist during a partially recovered accident scenario, similar to the one that occurred in TMI - 2. In particular this analysis aims to compare the impact of core degradation morphology on quenching models inherent within the two codes and the coolability of debris during partially recovered accidents. A primary motivation for this study is the development of insights into how uncertainties in core damage progression models impact the ability to assess the potential for recovery of a degraded core. These quench and core recovery models are of the most interest when there is a significant amount of core damage, but intact and degraded fuel still remain in the cor e region or the lower plenum. Accordingly this analysis presents a spectrum of partially recovered accident scenarios by varying both water injection timing and rate to highlight the impact of core degradation phenomena on recovered accident scenarios. This analysis uses the newly released MELCOR 2.2 rev. 966 5 and MAAP5, Version 5.04. These code versions, which incorporate a significant number of modifications that have been driven by analyses and forensic evidence obtained from the Fukushima - Daiichi reactor site.

  1. Adding Archival Finding Aids to the Library Catalogue: Simple Crosswalk or Data Traffic Jam?

    Directory of Open Access Journals (Sweden)

    Geoff Brown

    2007-12-01

    Full Text Available Dalhousie University Archives and Special Collections (DUASCSC has been producing Encoded Archival Description (EAD finding aids to describe its archival collections since 2003. The EAD descriptions started as a way to convert the collection of print and electronic (MS Word and WordPerfect finding aids into a stable, software neutral format. As the collection of finding aids grew it became apparent that we needed a way to search these documents beyond what was possible via a basic browse on the DUASC website. As a result, we embarked on a systematic crosswalk of the EAD finding aids into MARC format for inclusion in the Novanet library catalogue. This has facilitated searching and discovery of the materials by a much broader audience of Dalhousie University Library users as well as users from all of the other Novanet member libraries in Nova Scotia and the general public. This article describes the primary motivation for the project and the technical aspects of converting the EAD finding aids into MARC format for inclusion in the Novanet catalogue.

  2. Distortions in processed signals and their application in electronic design - III: An automated generator of communication jamming signals

    International Nuclear Information System (INIS)

    Njau, E.C.

    1987-10-01

    We describe the design and operational features of a simple electronic circuit that is capable of automatically generating a narrow bandwidth jamming signal around each frequency signal received from target transmitters. It is noted that jamming based upon this circuit is fairly difficult to nullify using some of the conventional ''counter jamming'' strategies since in this case the jamming signals are flexibly locked onto the spectral components of the received signals. (author). 3 refs, 3 figs

  3. Circuit Design for Sensor Detection Signal Conditioner Nitrate Content

    Directory of Open Access Journals (Sweden)

    Robeth Manurung

    2011-09-01

    Full Text Available Nitrate is one of macro nutrients very important for agriculture. The availability of nitrate in soil is limited because it is very easy to leaching by rain, therefore nitrate could be contaminated ground water by  over-process of fertilizer. This process could also produce inefficiency in agriculture if it happened continuesly without pre-analysis of farm field. The answer those problems, it is need to develop the ion sensor system to measure concentrations of nitrat in soil. The system is consist of nitrate ion sensor device, signal conditioning and data acquisition circuit. The design and fabrications of signal conditioning circuit which integrated into ion nitrate sensor system and will apply for agriculture. This sensor has been used amperometric with three electrodes configuration: working, reference  and auxiliarry; the ion senstive membrane has use conductive polymer. The screen printing technique has been choosen to fabricate electrodes and deposition technique for ion sensitive membrane is electropolymerization. The characterization of sensor has been conducted using nitrate standard solution with range of concentration between 1 µM–1 mM. The characterization has shown that sensor has a good response with cureent output between 2.8–4.71 µA, liniearity factor is 99.65% and time response 250 second.

  4. Evolutionary design optimization of traffic signals applied to Quito city.

    Science.gov (United States)

    Armas, Rolando; Aguirre, Hernán; Daolio, Fabio; Tanaka, Kiyoshi

    2017-01-01

    This work applies evolutionary computation and machine learning methods to study the transportation system of Quito from a design optimization perspective. It couples an evolutionary algorithm with a microscopic transport simulator and uses the outcome of the optimization process to deepen our understanding of the problem and gain knowledge about the system. The work focuses on the optimization of a large number of traffic lights deployed on a wide area of the city and studies their impact on travel time, emissions and fuel consumption. An evolutionary algorithm with specialized mutation operators is proposed to search effectively in large decision spaces, evolving small populations for a short number of generations. The effects of the operators combined with a varying mutation schedule are studied, and an analysis of the parameters of the algorithm is also included. In addition, hierarchical clustering is performed on the best solutions found in several runs of the algorithm. An analysis of signal clusters and their geolocation, estimation of fuel consumption, spatial analysis of emissions, and an analysis of signal coordination provide an overall picture of the systemic effects of the optimization process.

  5. Signalling design and architecture for a proposed mobile satellite network

    Science.gov (United States)

    Yan, T.-Y.; Cheng, U.; Wang, C.

    1990-01-01

    In a frequency-division/demand-assigned multiple-access (FD/DAMA) architecture, each mobile subscriber must make a connection request to the Network Management Center before transmission for either open-end or closed-end services. Open-end services are for voice calls and long file transfer and are processed on a blocked-call-cleared basis. Closed-end services are for transmitting burst data and are processed on a first-come first-served basis. This paper presents the signalling design and architecture for non-voice services of an FD/DAMA mobile satellite network. The connection requests are made through the recently proposed multiple channel collision resolution scheme which provides a significantly higher throughput than the traditional slotted ALOHA scheme. For non-voice services, it is well known that retransmissions are necessary to ensure the delivery of a message in its entirety from the source to destination. Retransmission protocols for open-end and closed-end data transfer are investigated. The signal structure for the proposed network is derived from X-25 standards with appropriate modifications. The packet types and their usages are described in this paper.

  6. Teaching Guide for the Traffic Signal Light Program: Kindergarten Level.

    Science.gov (United States)

    Maryland State Dept. of Education, Baltimore.

    This teachers' guide provides materials and suggestions for approximately 125 lessons that are designed to increase kindergarten children's traffic safety skills and knowledge. Most of the guide focuses on (1) lessons about physical structures in the pedestrian environment such as sidewalks, curbs, crosswalks, and intersections, and (2) signal…

  7. Dynamic analysis of pedestrian crossing behaviors on traffic flow at unsignalized mid-block crosswalks

    Science.gov (United States)

    Liu, Gang; He, Jing; Luo, Zhiyong; Yang, Wunian; Zhang, Xiping

    2015-05-01

    It is important to study the effects of pedestrian crossing behaviors on traffic flow for solving the urban traffic jam problem. Based on the Nagel-Schreckenberg (NaSch) traffic cellular automata (TCA) model, a new one-dimensional TCA model is proposed considering the uncertainty conflict behaviors between pedestrians and vehicles at unsignalized mid-block crosswalks and defining the parallel updating rules of motion states of pedestrians and vehicles. The traffic flow is simulated for different vehicle densities and behavior trigger probabilities. The fundamental diagrams show that no matter what the values of vehicle braking probability, pedestrian acceleration crossing probability, pedestrian backing probability and pedestrian generation probability, the system flow shows the "increasing-saturating-decreasing" trend with the increase of vehicle density; when the vehicle braking probability is lower, it is easy to cause an emergency brake of vehicle and result in great fluctuation of saturated flow; the saturated flow decreases slightly with the increase of the pedestrian acceleration crossing probability; when the pedestrian backing probability lies between 0.4 and 0.6, the saturated flow is unstable, which shows the hesitant behavior of pedestrians when making the decision of backing; the maximum flow is sensitive to the pedestrian generation probability and rapidly decreases with increasing the pedestrian generation probability, the maximum flow is approximately equal to zero when the probability is more than 0.5. The simulations prove that the influence of frequent crossing behavior upon vehicle flow is immense; the vehicle flow decreases and gets into serious congestion state rapidly with the increase of the pedestrian generation probability.

  8. Analog Filter Design Rules for Multilevel Polybinary Signaling Generation

    DEFF Research Database (Denmark)

    Vegas Olmos, Juan José; Cavallero, Francisco javier Vaquero; Tafur Monroy, Idelfonso

    2014-01-01

    Polybinary signaling has gained attention lately due to its generation simplicity and reduced spectral usage. This paper presents a study on the requirements for analog filters for the generation of multilevel polybinary signals with three to nine levels.......Polybinary signaling has gained attention lately due to its generation simplicity and reduced spectral usage. This paper presents a study on the requirements for analog filters for the generation of multilevel polybinary signals with three to nine levels....

  9. Quantification, modelling and design for signal history dependent effects in mixed-signal SOI/SOS circuits

    International Nuclear Information System (INIS)

    Edwards, C.F.; Redman-White, W.; Bracey, M.; Tenbroek, B.M.; Lee, M.S.; Uren, M.J.; Brunson, K.M.

    1999-01-01

    This paper deals with how the radiation hardness of mixed signal SOI/SOS CMOS circuits is taken into account at both architectural terms as well as the the transistor level cell designs. The primary issue is to deal with divergent transistor threshold shifts, and to understand the effects of large amplitude non stationary signals on analogue cell behaviour. (authors)

  10. Design of the Chaotic Signal Generator Based on LABVIEW

    Directory of Open Access Journals (Sweden)

    Jian-Guo Zhang

    2014-01-01

    Full Text Available We introduces a new method that can achieve the generation of Colpitts chaotic signal The system is based on virtual instrument platform and combined with MATLAB calculation to achieve the generation of Colpitts chaotic signal and making it analysis with autocorrelation and power spectrum at the same time. Signal channel output of chaotic signal was realized through USB-6009 acquisition module extending DA5405 high-speed DAC (Digital-to-Analog Converter chip. The system can adjust parameters based on customers’ requirements to achieve different frequency chaotic signal generation. Compared with the traditional autonomy Colpitts chaotic signal generator, this generator is simple and clear in structure, simple to operate, strong stability, easy to achieve etc.

  11. Digital signal display board design: A knowledge based study

    International Nuclear Information System (INIS)

    Chaitanya, V. Sree Krishna; Rao, C. Raghavendra

    2007-01-01

    The digital signal display board is assumed to be composed of picture tubes for the purpose of displaying characters. The signal board with the picture tubes constitutes an Information System. A methodology for obtaining the discrimable matrix or table (more decisive attributes) and knowledge reduction for the above information system is proposed

  12. Explaining reduction of pedestrian–motor vehicle crashes in Arkhangelsk, Russia, in 2005–2010

    Directory of Open Access Journals (Sweden)

    Alexander V. Kudryavtsev

    2012-09-01

    Full Text Available Objective. To explain a reduction in pedestrian–motor vehicle crashes in Arkhangelsk, Russia, in 2005–2010. Study design. Retrospective ecological study. Methods. For 2005–2010, police data on pedestrian–motor vehicle crashes, traffic violations, and total motor vehicles (MVs were combined with data on changes in national road traffic legislation and municipal road infrastructure. Negative binomial regression was used to investigate trends in monthly rates of pedestrian–motor vehicle crashes per total MVs and estimate changes in these rates per unit changes in the safety measures. Results. During the 6 years, the police registered 2,565 pedestrian–motor vehicle crashes: 1,597 (62% outside crosswalks, 766 (30% on non-signalized crosswalks, and 202 (8% on signalized crosswalks. Crash rates outside crosswalks and on signalized crosswalks decreased on average by 1.1% per month, whereas the crash rate on non-signalized crosswalks remained unchanged. Numbers of signalized and non-signalized crosswalks increased by 14 and 19%, respectively. Also, 10% of non-signalized crosswalks were combined with speed humps, and 4% with light-reflecting vertical signs. Pedestrian penalties for traffic violations increased 4-fold. Driver penalties for ignoring prohibiting signal and failure to give way to pedestrian on non-signalized crosswalk increased 7- and 8-fold, respectively. The rate of total registered drivers’ traffic violations per total MVs decreased on average by 0.3% per month. All studied infrastructure and legislative measures had inverse associations with the rate of crashes outside crosswalks. The rate of crashes on signalized crosswalks showed inverse associations with related monetary penalties. Conclusions. The introduction of infrastructure and legislative measures is the most probable explanation of the reduction of pedestrian–motor vehicle crashes in Arkhangelsk. The overall reduction is due to decreases in rates of crashes

  13. The Mixed-Signal ASIC design course at Twente

    NARCIS (Netherlands)

    Stehelin, G.; Tangelder, R.J.W.T.; Gerez, Sabih H.; Kerkhoff, Hans G.; Klumperink, Eric A.M.; Smit, J.; Snijders, H.; Speek, H.; de Vries, H.

    2000-01-01

    In this paper we give a detailed overview of the ASIC design course as it is being given at the Department of Electrical Engineering of the University of Twente. This course covers the complete trajectory from system design via circuit design and actual implementation to testing. Design and testing

  14. Linking proteins to signaling pathways for experiment design and evaluation.

    Directory of Open Access Journals (Sweden)

    Illés J Farkas

    Full Text Available Biomedical experimental work often focuses on altering the functions of selected proteins. These changes can hit signaling pathways, and can therefore unexpectedly and non-specifically affect cellular processes. We propose PathwayLinker, an online tool that can provide a first estimate of the possible signaling effects of such changes, e.g., drug or microRNA treatments. PathwayLinker minimizes the users' efforts by integrating protein-protein interaction and signaling pathway data from several sources with statistical significance tests and clear visualization. We demonstrate through three case studies that the developed tool can point out unexpected signaling bias in normal laboratory experiments and identify likely novel signaling proteins among the interactors of known drug targets. In our first case study we show that knockdown of the Caenorhabditis elegans gene cdc-25.1 (meant to avoid progeny may globally affect the signaling system and unexpectedly bias experiments. In the second case study we evaluate the loss-of-function phenotypes of a less known C. elegans gene to predict its function. In the third case study we analyze GJA1, an anti-cancer drug target protein in human, and predict for this protein novel signaling pathway memberships, which may be sources of side effects. Compared to similar services, a major advantage of PathwayLinker is that it drastically reduces the necessary amount of manual literature searches and can be used without a computational background. PathwayLinker is available at http://PathwayLinker.org. Detailed documentation and source code are available at the website.

  15. Model-based design of self-Adapting networked signal processing systems

    NARCIS (Netherlands)

    Oliveira Filho, J.A. de; Papp, Z.; Djapic, R.; Oostveen, J.C.

    2013-01-01

    The paper describes a model based approach for architecture design of runtime reconfigurable, large-scale, networked signal processing applications. A graph based modeling formalism is introduced to describe all relevant aspects of the design (functional, concurrency, hardware, communication,

  16. Automated Design Tools for Integrated Mixed-Signal Microsystems (NeoCAD)

    National Research Council Canada - National Science Library

    Petre, P; Visher, J; Shringarpure, R; Valley, F; Swaminathan, M

    2005-01-01

    Automated design tools and integrated design flow methodologies were developed that demonstrated more than an order- of-magnitude reduction in cycle time and cost for mixed signal (digital/analoglRF...

  17. Design principles of paradoxical signaling in the immune system

    Science.gov (United States)

    Hart, Yuval

    A widespread feature of cell-cell signaling systems is paradoxical pleiotropy: the same secreted signaling molecule can induce opposite effects in the responding cells. For example, the cytokine IL-2 can promote proliferation and death of T-cells. The role of such paradoxical signaling remains unclear. We suggest that this mechanism provides homeostatic concentration of cells, independent of initial conditions. The crux of the paradoxical mechanism is the combination of a positive and a negative feedback loops creating two stable states - an OFF state and an ON state. Experimentally, we found that CD4 + cells grown in culture with a 30-fold difference in initial concentrations reached a homeostatic concentration nearly independent of initial cell levels (ON-state). Below an initial threshold, cell density decayed to extinction (OFF-state). Mathematical modeling explained the observed cell and cytokine dynamics and predicted conditions that shifted cell fate from homeostasis to the OFF-state. We suggest that paradoxical signaling provides cell circuits with specific dynamical features that are robust to environmental perturbations.

  18. Non-linear and signal energy optimal asymptotic filter design

    Directory of Open Access Journals (Sweden)

    Josef Hrusak

    2003-10-01

    Full Text Available The paper studies some connections between the main results of the well known Wiener-Kalman-Bucy stochastic approach to filtering problems based mainly on the linear stochastic estimation theory and emphasizing the optimality aspects of the achieved results and the classical deterministic frequency domain linear filters such as Chebyshev, Butterworth, Bessel, etc. A new non-stochastic but not necessarily deterministic (possibly non-linear alternative approach called asymptotic filtering based mainly on the concepts of signal power, signal energy and a system equivalence relation plays an important role in the presentation. Filtering error invariance and convergence aspects are emphasized in the approach. It is shown that introducing the signal power as the quantitative measure of energy dissipation makes it possible to achieve reasonable results from the optimality point of view as well. The property of structural energy dissipativeness is one of the most important and fundamental features of resulting filters. Therefore, it is natural to call them asymptotic filters. The notion of the asymptotic filter is carried in the paper as a proper tool in order to unify stochastic and non-stochastic, linear and nonlinear approaches to signal filtering.

  19. Design of General-purpose Industrial signal acquisition system in a large scientific device

    Science.gov (United States)

    Ren, Bin; Yang, Lei

    2018-02-01

    In order to measure the industrial signal of a large scientific device experiment, a set of industrial data general-purpose acquisition system has been designed. It can collect 4~20mA current signal and 0~10V voltage signal. Through the practical experiments, it shows that the system is flexible, reliable, convenient and economical, and the system has characters of high definition and strong anti-interference ability. Thus, the system fully meets the design requirements..

  20. Mechanical design in embryos: mechanical signalling, robustness and developmental defects.

    Science.gov (United States)

    Davidson, Lance A

    2017-05-19

    Embryos are shaped by the precise application of force against the resistant structures of multicellular tissues. Forces may be generated, guided and resisted by cells, extracellular matrix, interstitial fluids, and how they are organized and bound within the tissue's architecture. In this review, we summarize our current thoughts on the multiple roles of mechanics in direct shaping, mechanical signalling and robustness of development. Genetic programmes of development interact with environmental cues to direct the composition of the early embryo and endow cells with active force production. Biophysical advances now provide experimental tools to measure mechanical resistance and collective forces during morphogenesis and are allowing integration of this field with studies of signalling and patterning during development. We focus this review on concepts that highlight this integration, and how the unique contributions of mechanical cues and gradients might be tested side by side with conventional signalling systems. We conclude with speculation on the integration of large-scale programmes of development, and how mechanical responses may ensure robust development and serve as constraints on programmes of tissue self-assembly.This article is part of the themed issue 'Systems morphodynamics: understanding the development of tissue hardware'. © 2017 The Author(s).

  1. Correction of rhodium detector signals for comparison to design calculations

    International Nuclear Information System (INIS)

    Judd, J.L.; Chang, R.Y.; Gabel, C.W.

    1989-01-01

    Rhodium detectors are used in many commercial pressurized water reactors PWRs [pressurized water reactor] as in-core neutron detectors. The signals from the detectors are the result of neutron absorption in 103 Rh and the subsequent beta decay of 104 Rh to 104 Pd. The rhodium depletes ∼1% per full-power month, so corrections are necessary to the detector signal to account for the effects of the rhodium depletion. These corrections result from the change in detector self-shielding with rhodium burnup and the change in rhodium concentration itself. Correction for the change in rhodium concentration is done by multiplication of the factor N(t)/N 0 , where N(t) is the rhodium concentration at time t and N 0 is the initial rhodium concentration. The calculation of the self-shielding factor is more complicated and is presented. A self-shielding factor based on the fraction of rhodium remaining was calculated with the CASMO-3 code. The results obtained from our comparisons of predicted and measured in-core detector signals show that the CASMO-3/SIMULATE-3 code package is an effective tool for estimating pin peaking and power distributions

  2. The influence of traffic signal solutions on self-reported road-crossing behavior.

    Science.gov (United States)

    Di Stasi, Leandro L; Megías, Alberto; Cándido, Antonio; Maldonado, Antonio; Catena, Andrés

    2015-01-07

    Injury to pedestrians is a major safety hazard in many countries. Since the beginning of the last century, modern cities have been designed around the use of motor vehicles despite the unfavourable interactions between the vehicles and pedestrians. This push towards urbanization resulted in a substantial number of crashes and fatalities involving pedestrians every day, all over the world. Thus, improving the design of urban cities and townships is a pressing issue for modern society. The study presented here provides a characterization of pedestrian safety problems, with the emphasis on signalized crosswalks (i.e. traffic signal) design solutions. We tested the impact of seven different traffic light configurations (steady [green, yellow, and red], flashing [green, yellow, and red], and light off) on pedestrian self-reported road-crossing behavior, using a 11-point scale -ranging from 0 ("I never cross in this situation") to 10 ("I always cross in this situation"). Results showed that mandatory solutions (steady green vs. steady red) are the best solutions to avoid unsafe pedestrian behaviors while crossing controlled intersections (frequency of crossing: Mgreen = 9.4 ± 1 vs. Mred = 2.6 ± 2). These findings offer important guidelines for the design of future traffic signals for encouraging a pedestrian/transit-friendly environment.

  3. On signal design by the R/0/ criterion for non-white Gaussian noise channels

    Science.gov (United States)

    Bordelon, D. L.

    1977-01-01

    The use of the cut-off rate criterion for modulation system design is investigated for channels with non-white Gaussian noise. A signal space representation of the waveform channel is developed, and the cut-off rate for vector channels with additive non-white Gaussian noise and unquantized demodulation is derived. When the signal input to the channel is a continuous random vector, maximization of the cut-off rate with constrained average signal energy leads to a water-filling interpretation of optimal energy distribution in signal space. The necessary condition for a finite signal set to maximize the cut-off rate with constrained energy and an equally likely probability assignment of signal vectors is presented, and an algorithm is outlined for numerically computing the optimum signal set. As an example, the rectangular signal set which has the water-filling average energy distribution and the optimum rectangular set are compared.

  4. Note: The design of thin gap chamber simulation signal source based on field programmable gate array

    International Nuclear Information System (INIS)

    Hu, Kun; Wang, Xu; Li, Feng; Jin, Ge; Lu, Houbing; Liang, Futian

    2015-01-01

    The Thin Gap Chamber (TGC) is an important part of ATLAS detector and LHC accelerator. Targeting the feature of the output signal of TGC detector, we have designed a simulation signal source. The core of the design is based on field programmable gate array, randomly outputting 256-channel simulation signals. The signal is generated by true random number generator. The source of randomness originates from the timing jitter in ring oscillators. The experimental results show that the random number is uniform in histogram, and the whole system has high reliability

  5. Method of test signal design for estimating the aircraft aerodynamic parameters

    Science.gov (United States)

    Belokon', S. A.; Zolotukhin, Yu. N.; Filippov, M. N.

    2017-07-01

    A method of test signal design is proposed for studying the aircraft aerodynamic characteristics with the use of the technology of dynamically scaled free-flight models. Simultaneous excitation of all input channels in a prescribed frequency band by a set of mutually orthogonal signals is applied to increase the efficiency. A modified method of calculating the set of mutually orthogonal sinusoidal signals with a small normalized peak factor is presented. Results of simulating the aircraft motion in the MATLAB/Simulink environment with the use of the developed method of test signal design are reported.

  6. Design and analysis of UW-OFDM signals.

    Science.gov (United States)

    Huemer, Mario; Hofbauer, Christian; Onic, Alexander; Huber, Johannes B

    2014-10-01

    Unique word-orthogonal frequency division multiplexing (UW-OFDM) is a novel signaling concept where the guard interval is implemented as a deterministic sequence, the so-called unique word. The UW is generated by introducing a certain level of redundancy in the frequency domain. Different data estimation strategies and the favourable bit error ratio (BER) performance of UW-OFDM, as well as comparisons to competing concepts have already extensively been discussed in previous papers. This work focuses on the different possibilities on how to generate UW-OFDM signals. The optimality of the two-step over the direct approach in systematic UW-OFDM is proved analytically, we present a heuristic algorithm that allows a fast numerical optimization of the redundant subcarrier positions, and we show that our original intuitive approach of spreading the redundant subcarriers in systematically encoded UW-OFDM by minimizing the mean redundant energy is practically also optimum w.r.t. transceiver based cost functions. Finally, we derive closed form approximations of the statistical symbol distributions on individual subcarriers as well as the redundant energy distribution and compare them with numerically found results.

  7. Designs of precoding for LTE TDD using cell specific reference signals

    DEFF Research Database (Denmark)

    Sun, Fan; Lu, Lu; Sørensen, Troels Bundgaard

    2010-01-01

    We design non-codebook-based Multiple-Input Multiple-Output (MIMO) precoding schemes using multiple cell-specific reference signals patterns for the time division duplex (TDD) mode of LTE, where channel reciprocity can be exploited. Previously proposed non-codebookbased precoding schemes typically...... use UE specific reference signals for demodulation. Cell specific reference signals are however always allocated for the transmission of common control signalling, mobility measurements and downlink channel quality measurements. In order to save the resources occupied by UE specific reference signals...

  8. A new traffic control design method for large networks with signalized intersections

    Science.gov (United States)

    Leininger, G. G.; Colony, D. C.; Seldner, K.

    1979-01-01

    The paper presents a traffic control design technique for application to large traffic networks with signalized intersections. It is shown that the design method adopts a macroscopic viewpoint to establish a new traffic modelling procedure in which vehicle platoons are subdivided into main stream queues and turning queues. Optimization of the signal splits minimizes queue lengths in the steady state condition and improves traffic flow conditions, from the viewpoint of the traveling public. Finally, an application of the design method to a traffic network with thirty-three signalized intersections is used to demonstrate the effectiveness of the proposed technique.

  9. Design of the Acoustic Signal Receiving Unit of Acoustic Telemetry While Drilling

    Directory of Open Access Journals (Sweden)

    Li Zhigang

    2016-01-01

    Full Text Available Signal receiving unit is one of the core units of the acoustic telemetry system. A new type of acoustic signal receiving unit is designed to solve problems of the existing devices. The unit is a short joint in whole. It not only can receive all the acoustic signals transmitted along the drill string, without losing any signal, but will not bring additional vibration and interference. In addition, the structure of the amplitude transformer is designed, which can amplify the signal amplitude and improve the receiving efficiency. The design of the wireless communication module makes the whole device can be used in normal drilling process when the drill string is rotating. So, it does not interfere with the normal drilling operation.

  10. Design and implementation of a hybrid circuit system for micro sensor signal processing

    International Nuclear Information System (INIS)

    Wang Zhuping; Chen Jing; Liu Ruqing

    2011-01-01

    This paper covers a micro sensor analog signal processing circuit system (MASPS) chip with low power and a digital signal processing circuit board implementation including hardware connection and software design. Attention has been paid to incorporate the MASPS chip into the digital circuit board. The ultimate aim is to form a hybrid circuit used for mixed-signal processing, which can be applied to a micro sensor flow monitoring system. (semiconductor integrated circuits)

  11. Designing signal-enriched triggers for boosted jets.

    CERN Document Server

    Toumazou, Marina

    2017-01-01

    Triggers designed to favour the selection of hadronically decaying massive particles have been studied. Both triggers using solely ET and mass cuts (similar to new 2017 triggers) and triggers exploiting polarization information have been studied. The mass cut triggers show substantial gains in rate reduction, while the benefits of polarization triggers are less obvious. The final conclusion is that it is more useful to identify and trigger on generic boosted decays, irrespective of the polarization of the decaying particle

  12. Extreme low-power mixed signal IC design

    CERN Document Server

    Tajalli, Armin

    2010-01-01

    This book describes a completely novel class of techniques for designing ultra-low-power integrated circuits (ICs). In many applications such as battery operated systems and battery-less (energy-scavenging) systems, power dissipation is a critical parameter. As a result, there is a growing demand for reducing the power (energy) consumption in ICs to extremely low levels, not achievable by using classical ""subthreshold CMOS"" techniques. This book introduces a new family of ""subthreshold circuits"" called ""source-coupled circuits"". This family of circuits can be used for implementing digita

  13. Design of eight-channel ADC card for GHz signal conversion

    CERN Document Server

    Habib, Samer Bou; Jalmuzna, Wojciech; Jezynski, Tomasz

    2011-01-01

    This paper describes the design of an eight-channel ATCA card suited for direct analog-to-digital conversion of 1.3 GHz signals with a maximum ADC clock frequency of 500 MHz. The undersampling operation is used for signal conversion. This card was designed for the needs of the LLRF system of the FLASH and XFEL accelerators. The designed module consists of a main ATCA board with eight ADCs, FPGA unit, memory, power supply and diagnostic circuits. The main ATCA card allows connecting a daughter board with IPMI, CPU and fast interfaces for communication purposes. This paper describes such issues as system organization allowing acquisition of data at such high data rates, circuit synchronization by high-quality clock signals, CPU and connectivity features, 20-layer PCB design and techniques used for high-frequency signals transmission and matching.

  14. Design of EEG Signal Acquisition System Using Arduino MEGA1280 and EEGAnalyzer

    Directory of Open Access Journals (Sweden)

    Saptono Debyo

    2016-01-01

    Full Text Available This study integrates the hardware circuit design and software development to achieve a 16 channels Electroencephalogram (EEG system for Brain Computer Interface (BCI applications. Signals obtained should be strong enough amplitude that is usually expressed in units of millivolts and reasonably clean of noise that appears when the data acquisition process. The process of data acquisition consists of two stages are the acquisition of the original EEG signal can be done by the active electrode with an instrumentation amplifier or a preamplifier and processing the signal to get better signals with improved signal quality by removing noise using filters with IC OPAMP. The design of a preamplifier with high common-mode rejection ratio and high signal-to-noise ratio is very important. Moreover, the friction between the electrode pads and the skin as well as the design of dual power supply. Designs used single-power AC-coupled circuit, which effectively reduces the DC bias and improves the error caused by the effects of part errors. At the same time, the digital way is applied to design the adjustable amplification and filter function, which can design for different EEG frequency bands. The next step, those EEG signals received by the microcontroller through a port Analog to Digital Converter (ADC that integrated and converted into digital signals and stored in the RAM of microcontroller which simultaneously at 16 ports in accordance with the minimal number of points of data collection on the human scalp. Implementation results have shown the series of acquisitions to work properly so that it can be displayed EEG signals via software EEGAnalyzer.

  15. Distortions in processed signals and their application in electronic design - I: Basic and general formulations

    International Nuclear Information System (INIS)

    Njau, E.C.

    1987-10-01

    Complete analytical expressions for the distortion signals introduced into analogue signals by sampling and quantization processes are developed. These expressions are made up of terms that are wholely functions of the parameters of the original signals involved and hence are easy to evaluate numerically. It is shown in Parts 2 and 3 of this series that these expressions may be successfully used in the design and development of some electronic devices whose operation depends upon the above-named distortion signals. (author). 7 refs

  16. The Signal Detection and Control Circuit Design for Confocal Auto-Focus System

    OpenAIRE

    Yin Liu; Jin Yu; Zeqiang Mo

    2016-01-01

    Based on the demands of Confocal Auto-Focus system, the implementation method of signal measurement circuit and control circuit is given. Using the high performance instrumental amplifier AD620BN, low noise precision FET Op amplifier AD795JRZ and ultralow offset voltage Op amplifier OP07EP, a signal measurement circuit used to converse the two differential light intensity signal to electric signal is designed. And a control circuit which takes MCU MSP430F149 as core processes the former signa...

  17. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    International Nuclear Information System (INIS)

    Zhou Xu; Liu Congzhan; Zhao Jianling

    2014-01-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically. (authors)

  18. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    Science.gov (United States)

    Zhou, Xu; Liu, Cong-Zhan; Zhao, Jian-Ling; Zhang, Fei; Zhang, Yi-Fei; Li, Zheng-Wei; Zhang, Shuo; Li, Xu-Fang; Lu, Xue-Feng; Xu, Zhen-Ling; Lu, Fang-Jun

    2014-02-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically.

  19. Reconfigurable signal processor designs for advanced digital array radar systems

    Science.gov (United States)

    Suarez, Hernan; Zhang, Yan (Rockee); Yu, Xining

    2017-05-01

    The new challenges originated from Digital Array Radar (DAR) demands a new generation of reconfigurable backend processor in the system. The new FPGA devices can support much higher speed, more bandwidth and processing capabilities for the need of digital Line Replaceable Unit (LRU). This study focuses on using the latest Altera and Xilinx devices in an adaptive beamforming processor. The field reprogrammable RF devices from Analog Devices are used as analog front end transceivers. Different from other existing Software-Defined Radio transceivers on the market, this processor is designed for distributed adaptive beamforming in a networked environment. The following aspects of the novel radar processor will be presented: (1) A new system-on-chip architecture based on Altera's devices and adaptive processing module, especially for the adaptive beamforming and pulse compression, will be introduced, (2) Successful implementation of generation 2 serial RapidIO data links on FPGA, which supports VITA-49 radio packet format for large distributed DAR processing. (3) Demonstration of the feasibility and capabilities of the processor in a Micro-TCA based, SRIO switching backplane to support multichannel beamforming in real-time. (4) Application of this processor in ongoing radar system development projects, including OU's dual-polarized digital array radar, the planned new cylindrical array radars, and future airborne radars.

  20. Circuit Design to Stabilize the Reflectometer Local Oscillator Signals

    International Nuclear Information System (INIS)

    Kung CC; Kramer GJ; Johnson E; Solomon W; Nazikian R.

    2005-01-01

    Reflectometry, which uses the microwave radar technique to probe the magnetically confined fusion plasmas, is a very powerful tool to observe the density fluctuations in the fusion plasmas. Typically, two or more microwave beams of different frequencies are used to study the plasma density fluctuations. The frequency separation between these two beams of the PPPL designed reflectometer system upgrade on the DIII-D tokamak can be varied over 18 GHz. Due to the performance of the associated electronics, the local oscillator (LO) power level at the LO port of the I/Q demodulator suffers more than 12 dB of power fluctuations when the frequency separation is varied. Thus, the I/Q demodulator performance is impaired. In order to correct this problem, a power leveling circuit is introduced in the PPPL upgrade. According to the test results, the LO power fluctuation was regulated to be within 1 dB for greater than 16 dB of input power variation over the full dynamic bandwidth of the receiver

  1. Circuit Design to Stabilize the Reflectometer Local Oscillator Signals

    Energy Technology Data Exchange (ETDEWEB)

    Kung, C. C.; Kramer, G. J.; Johnson, E.; Solomon, W.; Nazikian, R.

    2005-10-04

    Reflectometry, which uses the microwave radar technique to probe the magnetically confined fusion plasmas, is a very powerful tool to observe the density fluctuations in the fusion plasmas. Typically, two or more microwave beams of different frequencies are used to study the plasma density fluctuations. The frequency separation between these two beams of the PPPL designed reflectometer system upgrade on the DIII-D tokamak can be varied over 18 GHz. Due to the performance of the associated electronics, the local oscillator (LO) power level at the LO port of the I/Q demodulator suffers more than 12 dB of power fluctuations when the frequency separation is varied. Thus, the I/Q demodulator performance is impaired. In order to correct this problem, a power leveling circuit is introduced in the PPPL upgrade. According to the test results, the LO power fluctuation was regulated to be within 1 dB for greater than 16 dB of input power variation over the full dynamic bandwidth of the receiver.

  2. Traffic signal design and simulation for vulnerable road users safety and bus preemption

    International Nuclear Information System (INIS)

    Lo, Shih-Ching; Huang, Hsieh-Chu

    2015-01-01

    Mostly, pedestrian car accidents occurred at a signalized interaction is because pedestrians cannot across the intersection safely within the green light. From the viewpoint of pedestrian, there might have two reasons. The first one is pedestrians cannot speed up to across the intersection, such as the elders. The other reason is pedestrians do not sense that the signal phase is going to change and their right-of-way is going to be lost. Developing signal logic to protect pedestrian, who is crossing an intersection is the first purpose of this study. In addition, to improve the reliability and reduce delay of public transportation service is the second purpose. Therefore, bus preemption is also considered in the designed signal logic. In this study, the traffic data of the intersection of Chong-Qing North Road and Min-Zu West Road, Taipei, Taiwan, is employed to calibrate and validate the signal logic by simulation. VISSIM 5.20, which is a microscopic traffic simulation software, is employed to simulate the signal logic. From the simulated results, the signal logic presented in this study can protect pedestrians crossing the intersection successfully. The design of bus preemption can reduce the average delay. However, the pedestrian safety and bus preemption signal will influence the average delay of cars largely. Thus, whether applying the pedestrian safety and bus preemption signal logic to an intersection or not should be evaluated carefully

  3. Traffic signal design and simulation for vulnerable road users safety and bus preemption

    Energy Technology Data Exchange (ETDEWEB)

    Lo, Shih-Ching; Huang, Hsieh-Chu [Department of Transportation Technology and Logistics Management, Chung Hua University, No. 707, Sec. 2, WuFu Rd., Hsinchu, 300, Taiwan (China)

    2015-01-22

    Mostly, pedestrian car accidents occurred at a signalized interaction is because pedestrians cannot across the intersection safely within the green light. From the viewpoint of pedestrian, there might have two reasons. The first one is pedestrians cannot speed up to across the intersection, such as the elders. The other reason is pedestrians do not sense that the signal phase is going to change and their right-of-way is going to be lost. Developing signal logic to protect pedestrian, who is crossing an intersection is the first purpose of this study. In addition, to improve the reliability and reduce delay of public transportation service is the second purpose. Therefore, bus preemption is also considered in the designed signal logic. In this study, the traffic data of the intersection of Chong-Qing North Road and Min-Zu West Road, Taipei, Taiwan, is employed to calibrate and validate the signal logic by simulation. VISSIM 5.20, which is a microscopic traffic simulation software, is employed to simulate the signal logic. From the simulated results, the signal logic presented in this study can protect pedestrians crossing the intersection successfully. The design of bus preemption can reduce the average delay. However, the pedestrian safety and bus preemption signal will influence the average delay of cars largely. Thus, whether applying the pedestrian safety and bus preemption signal logic to an intersection or not should be evaluated carefully.

  4. A basic study on universal design of auditory signals in automobiles.

    Science.gov (United States)

    Yamauchi, Katsuya; Choi, Jong-dae; Maiguma, Ryo; Takada, Masayuki; Iwamiya, Shin-ichiro

    2004-11-01

    In this paper, the impression of various kinds of auditory signals currently used in automobiles and a comprehensive evaluation were measured by a semantic differential method. The desirable acoustic characteristic was examined for each type of auditory signal. Sharp sounds with dominant high-frequency components were not suitable for auditory signals in automobiles. This trend is expedient for the aged whose auditory sensitivity in the high frequency region is lower. When intermittent sounds were used, a longer OFF time was suitable. Generally, "dull (not sharp)" and "calm" sounds were appropriate for auditory signals. Furthermore, the comparison between the frequency spectrum of interior noise in automobiles and that of suitable sounds for various auditory signals indicates that the suitable sounds are not easily masked. The suitable auditory signals for various purposes is a good solution from the viewpoint of universal design.

  5. Influence of approaching tram on behaviour of pedestrians in signalised crosswalks in Poland.

    Science.gov (United States)

    Kruszyna, Maciej; Rychlewski, Jeremi

    2013-06-01

    Research done in two Polish cities has uncovered an influence of an approaching tram on pedestrian behaviour. The measurements were done by counting pedestrians waiting for a green signal, crossing on red signal safely, or crossing on red signal taking a risk of being hit by a car, differentiating between pedestrians attempting to board a public transport vehicle and other pedestrians. It was expected, that pedestrian behaviour might be influenced by traffic control predictability, therefore two cities were chosen for the task: Wrocław with fixed time traffic control and Poznań with a majority of traffic responsive traffic signals. Data from the measurements was compared in order to find behaviour patterns - the comparison led to a conclusion, that an attempt to get on board of an incoming public transport vehicle can be a major cause for pedestrians to violate a red signal, including an increase of unsafe behaviour. These pedestrians may provoke other pedestrians to cross on a red signal. On the other hand if traffic control guarantees boarding the public transport vehicle, passengers-to-be may be even more obedient than other pedestrians. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. On signal design by the R sub 0 criterion for non-white Gaussian noise channels

    Science.gov (United States)

    Bordelon, D. L.

    1976-01-01

    The use of the R sub 0 criterion for modulation system design is investigated for channels with non-white Gaussian noise. A signal space representation of the waveform channel is developed, and the cut-off rate R sub 0 for vector channels with additive nonwhite Gaussian noise and unquantized demodulation is derived. When the signal unput to the channel is a continuous random vector, maximization of R sub 0 with constrained average signal energy leads to a water-filling interpretation of optimal energy distribution in signal space. The necessary condition for a finite signal set to maximize R sub 0 with constrained energy and an equally likely probability assignment of signal vectors is presented, and an algorithm is outlined for numerically computing the optimum signal set. A necessary condition on a constrained energy, finite signal set is found which maximizes a Taylor series approximation of R sub 0. This signal set is compared with the finite signal set which has the water-filling average energy distribution.

  7. Design of acoustic logging signal source of imitation based on field programmable gate array

    International Nuclear Information System (INIS)

    Zhang, K; Ju, X D; Lu, J Q; Men, B Y

    2014-01-01

    An acoustic logging signal source of imitation is designed and realized, based on the Field Programmable Gate Array (FPGA), to improve the efficiency of examining and repairing acoustic logging tools during research and field application, and to inspect and verify acoustic receiving circuits and corresponding algorithms. The design of this signal source contains hardware design and software design,and the hardware design uses an FPGA as the control core. Four signals are made first by reading the Random Access Memory (RAM) data which are inside the FPGA, then dealing with the data by digital to analog conversion, amplification, smoothing and so on. Software design uses VHDL, a kind of hardware description language, to program the FPGA. Experiments illustrate that the ratio of signal to noise for the signal source is high, the waveforms are stable, and also its functions of amplitude adjustment, frequency adjustment and delay adjustment are in accord with the characteristics of real acoustic logging waveforms. These adjustments can be used to imitate influences on sonic logging received waveforms caused by many kinds of factors such as spacing and span of acoustic tools, sonic speeds of different layers and fluids, and acoustic attenuations of different cementation planes. (paper)

  8. Design of acoustic logging signal source of imitation based on field programmable gate array

    Science.gov (United States)

    Zhang, K.; Ju, X. D.; Lu, J. Q.; Men, B. Y.

    2014-08-01

    An acoustic logging signal source of imitation is designed and realized, based on the Field Programmable Gate Array (FPGA), to improve the efficiency of examining and repairing acoustic logging tools during research and field application, and to inspect and verify acoustic receiving circuits and corresponding algorithms. The design of this signal source contains hardware design and software design,and the hardware design uses an FPGA as the control core. Four signals are made first by reading the Random Access Memory (RAM) data which are inside the FPGA, then dealing with the data by digital to analog conversion, amplification, smoothing and so on. Software design uses VHDL, a kind of hardware description language, to program the FPGA. Experiments illustrate that the ratio of signal to noise for the signal source is high, the waveforms are stable, and also its functions of amplitude adjustment, frequency adjustment and delay adjustment are in accord with the characteristics of real acoustic logging waveforms. These adjustments can be used to imitate influences on sonic logging received waveforms caused by many kinds of factors such as spacing and span of acoustic tools, sonic speeds of different layers and fluids, and acoustic attenuations of different cementation planes.

  9. Reference-tracking feedforward control design for linear dynamical systems through signal decomposition

    NARCIS (Netherlands)

    Kasemsinsup, Y.; Romagnoli, R.; Heertjes, M.F.; Weiland, S.; Butler, H.

    2017-01-01

    In this work, we study a novel approach towards the reference-tracking feedforward control design for linear dynamical systems. By utilizing the superposition property and exploiting signal decomposition together with a quadratic optimization process, we obtain a feedforward design procedure for

  10. Designing lymphocyte functional structure for optimal signal detection: voilà, T cells.

    Science.gov (United States)

    Noest, A J

    2000-11-21

    One basic task of immune systems is to detect signals from unknown "intruders" amidst a noisy background of harmless signals. To clarify the functional importance of many observed lymphocyte properties, I ask: What properties would a cell have if one designed it according to the theory of optimal detection, with minimal regard for biological constraints? Sparse and reasonable assumptions about the statistics of available signals prove sufficient for deriving many features of the optimal functional structure, in an incremental and modular design. The use of one common formalism guarantees that all parts of the design collaborate to solve the detection task. Detection performance is computed at several stages of the design. Comparison between design variants reveals e.g. the importance of controlling the signal integration time. This predicts that an appropriate control mechanism should exist. Comparing the design to reality, I find a striking similarity with many features of T cells. For example, the formalism dictates clonal specificity, serial receptor triggering, (grades of) anergy, negative and positive selection, co-stimulation, high-zone tolerance, and clonal production of cytokines. Serious mismatches should be found if T cells were hindered by mechanistic constraints or vestiges of their (co-)evolutionary history, but I have not found clear examples. By contrast, fundamental mismatches abound when comparing the design to immune systems of e.g. invertebrates. The wide-ranging differences seem to hinge on the (in)ability to generate a large diversity of receptors. Copyright 2000 Academic Press.

  11. Design and measurement of signal processing system for cavity beam position monitor

    International Nuclear Information System (INIS)

    Wang Baopeng; Leng Yongbin; Yu Luyang; Zhou Weimin; Yuan Renxian; Chen Zhichu

    2013-01-01

    In this paper, in order to achieve the output signal processing of cavity beam position monitor (CBPM), we develop a digital intermediate frequency receiver architecture based signal processing system, which consists of radio frequency (RF) front end and high speed data acquisition board. The beam position resolution in the CBPM signal processing system is superior to 1 μm. Two signal processing algorithms, fast Fourier transform (FFT) and digital down converter (DDC), are evaluated offline using MATLAB platform, and both can be used to achieve, the CW input signal, position resolutions of 0.31 μm and 0.10 μm at -16 dBm. The DDC algorithm for its good compatibility is downloaded into the FPGA to realize online measurement, reaching the position resolution of 0.49 μm due to truncation error. The whole system works well and the performance meets design target. (authors)

  12. Noise and signal interference in optical fiber transmission systems an optimum design approach

    CERN Document Server

    Bottacchi, Stefano

    2008-01-01

    A comprehensive reference to noise and signal interference in optical fiber communications Noise and Signal Interference in Optical Fiber Transmission Systems is a compendium on specific topics within optical fiber transmission and the optimization process of the system design. It offers comprehensive treatment of noise and intersymbol interference (ISI) components affecting optical fiber communications systems, containing coverage on noise from the light source, the fiber and the receiver. The ISI is modeled with a statistical approach, leading to new useful computational m

  13. An open-loop system design for deep space signal processing applications

    Science.gov (United States)

    Tang, Jifei; Xia, Lanhua; Mahapatra, Rabi

    2018-06-01

    A novel open-loop system design with high performance is proposed for space positioning and navigation signal processing. Divided by functions, the system has four modules, bandwidth selectable data recorder, narrowband signal analyzer, time-delay difference of arrival estimator and ANFIS supplement processor. A hardware-software co-design approach is made to accelerate computing capability and improve system efficiency. Embedded with the proposed signal processing algorithms, the designed system is capable of handling tasks with high accuracy over long period of continuous measurements. The experiment results show the Doppler frequency tracking root mean square error during 3 h observation is 0.0128 Hz, while the TDOA residue analysis in correlation power spectrum is 0.1166 rad.

  14. IIR digital filter design for powerline noise cancellation of ECG signal using arduino platform

    Science.gov (United States)

    Rahmatillah, Akif; Ataulkarim

    2017-05-01

    Powerline noise has been one of significant noises of Electrocardiogram (ECG) signal measurement. This noise is characterized by a sinusoidal signal which has 50 Hz of noise and 0.3 mV of maximum amplitude. This paper describes the design of IIR Notch filter design to reject a 50 Hz power line noise. IIR filter coefficients were calculated using pole placement method with three variations of band stop cut off frequencies of (49-51)Hz, (48 - 52)Hz, and (47 - 53)Hz. The algorithm and coefficients of filter were embedded to Arduino DUE (ARM 32 bit microcontroller). IIR notch filter designed has been able to reject power line noise with average square of error value of 0.225 on (49-51) Hz filter design and 0.2831 on (48 - 52)Hz filter design.

  15. Design of a signal conditioner for the Fermilab Magnet Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Giannelli, Pietro [Turin Polytechnic

    2012-01-01

    This thesis describes the design of a remotely-programmable signal conditioner for the harmonic measurement of accelerator magnets. A 10-channel signal conditioning circuit featuring bucking capabilities was designed from scratch and implemented to the level of the printed circuit board layout. Other system components were chosen from those available on the market. Software design was started with the definition of routine procedures. This thesis is part of an upgrade project for replacing obsolescent automated test equipment belonging to the Fermilab Magnet Test Facility. The design started with a given set of requirements. Using a top-down approach, all the circuits were designed and their expected performances were theoretically predicted and simulated. A limited prototyping phase followed. The printed circuit boards were laid out and routed using a CAD software and focusing the design on maximum electromagnetic interference immunity. An embedded board was selected for controlling and interfacing the signal conditioning circuitry with the instrumentation network. Basic low level routines for hardware access were defined. This work covered the entire design process of the signal conditioner, resulting in a project ready for manufacturing. The expected performances are in line with the requirements and, in the cases where this was not possible, approval of trade-offs was sought and received from the end users. Part I deals with the global structure of the signal conditioner and the subdivision in functional macro-blocks. Part II treats the hardware design phase in detail, covering the analog and digital circuits, the printed circuit layouts, the embedded controller and the power supply selection. Part III deals with the basic hardware-related routines to be implemented in the final software.

  16. Design and implementation of a multiband digital filter using FPGA to extract the ECG signal in the presence of different interference signals.

    Science.gov (United States)

    Aboutabikh, Kamal; Aboukerdah, Nader

    2015-07-01

    In this paper, we propose a practical way to synthesize and filter an ECG signal in the presence of four types of interference signals: (1) those arising from power networks with a fundamental frequency of 50Hz, (2) those arising from respiration, having a frequency range from 0.05 to 0.5Hz, (3) muscle signals with a frequency of 25Hz, and (4) white noise present within the ECG signal band. This was done by implementing a multiband digital filter (seven bands) of type FIR Multiband Least Squares using a digital programmable device (Cyclone II EP2C70F896C6 FPGA, Altera), which was placed on an education and development board (DE2-70, Terasic). This filter was designed using the VHDL language in the Quartus II 9.1 design environment. The proposed method depends on Direct Digital Frequency Synthesizers (DDFS) designed to synthesize the ECG signal and various interference signals. So that the synthetic ECG specifications would be closer to actual ECG signals after filtering, we designed in a single multiband digital filter instead of using three separate digital filters LPF, HPF, BSF. Thus all interference signals were removed with a single digital filter. The multiband digital filter results were studied using a digital oscilloscope to characterize input and output signals in the presence of differing sinusoidal interference signals and white noise. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Practical Consideration Factors to Design Array Configuration of Direction Finding System for Airborne Signal Intelligence

    Directory of Open Access Journals (Sweden)

    Jong-Hwan Lee

    2018-01-01

    Full Text Available Airborne signal intelligence (SIGINT systems must be capable of locating radio signal sources. Direction finding (DF to support this capability is an important factor. There are some practical considerations to be taken when designing the array configuration of a DF system for airborne SIGINT systems. This paper summarizes the practical factors when designing the array configuration of the DF system for airborne SIGINT. In particular, it focuses on four areas: antenna consideration factors when installing the DF system for airborne SIGINT from a practical point of view, array configuration methods for airborne communications intelligence and electronic intelligence, and a numerical analysis to select the optimum antenna position for airborne SIGINT.

  18. SOLUTION OF SIGNAL UNCERTAINTY PROBLEM AT ANALYTICAL DESIGN OF CONSECUTIVE COMPENSATOR IN PIEZO ACTUATOR CONTROL

    Directory of Open Access Journals (Sweden)

    S.V. Bystrov

    2016-05-01

    Full Text Available Subject of Research.We present research results for the signal uncertainty problem that naturally arises for the developers of servomechanisms, including analytical design of serial compensators, delivering the required quality indexes for servomechanisms. Method. The problem was solved with the use of Besekerskiy engineering approach, formulated in 1958. This gave the possibility to reduce requirements for input signal composition of servomechanisms by using only two of their quantitative characteristics, such as maximum speed and acceleration. Information about input signal maximum speed and acceleration allows entering into consideration the equivalent harmonic input signal with calculated amplitude and frequency. In combination with requirements for maximum tracking error, the amplitude and frequency of the equivalent harmonic effects make it possible to estimate analytically the value of the amplitude characteristics of the system by error and then convert it to amplitude characteristic of open-loop system transfer function. While previously Besekerskiy approach was mainly used in relation to the apparatus of logarithmic characteristics, we use this approach for analytical synthesis of consecutive compensators. Main Results. Proposed technique is used to create analytical representation of "input–output" and "error–output" polynomial dynamic models of the designed system. In turn, the desired model of the designed system in the "error–output" form of analytical representation of transfer functions is the basis for the design of consecutive compensator, that delivers the desired placement of state matrix eigenvalues and, consequently, the necessary set of dynamic indexes for the designed system. The given procedure of consecutive compensator analytical design on the basis of Besekerskiy engineering approach under conditions of signal uncertainty is illustrated by an example. Practical Relevance. The obtained theoretical results are

  19. Design of signal reception and processing system of embedded ultrasonic endoscope

    Science.gov (United States)

    Li, Ming; Yu, Feng; Zhang, Ruiqiang; Li, Yan; Chen, Xiaodong; Yu, Daoyin

    2009-11-01

    Embedded Ultrasonic Endoscope, based on embedded microprocessor and embedded real-time operating system, sends a micro ultrasonic probe into coelom through the biopsy channel of the Electronic Endoscope to get the fault histology features of digestive organs by rotary scanning, and acquires the pictures of the alimentary canal mucosal surface. At the same time, ultrasonic signals are processed by signal reception and processing system, forming images of the full histology of the digestive organs. Signal Reception and Processing System is an important component of Embedded Ultrasonic Endoscope. However, the traditional design, using multi-level amplifiers and special digital processing circuits to implement signal reception and processing, is no longer satisfying the standards of high-performance, miniaturization and low power requirements that embedded system requires, and as a result of the high noise that multi-level amplifier brought, the extraction of small signal becomes hard. Therefore, this paper presents a method of signal reception and processing based on double variable gain amplifier and FPGA, increasing the flexibility and dynamic range of the Signal Reception and Processing System, improving system noise level, and reducing power consumption. Finally, we set up the embedded experiment system, using a transducer with the center frequency of 8MHz to scan membrane samples, and display the image of ultrasonic echo reflected by each layer of membrane, with a frame rate of 5Hz, verifying the correctness of the system.

  20. Designing a Signal Conditioning System with Software Calibration for Resistor-feedback Patch Clamp Amplifier.

    Science.gov (United States)

    Hu, Gang; Zhu, Quanhui; Qu, Anlian

    2005-01-01

    In this paper, a programmable signal conditioning system based on software calibration for resistor-feedback patch clamp amplifier (PCA) has been described, this system is mainly composed of frequency correction, programmable gain and filter whose parameters are configured by software automatically to minimize the errors, A lab-designed data acquisition system (DAQ) is used to implement data collections and communications with PC. The laboratory test results show good agreement with design specifications.

  1. Modeling pedestrian crossing speed profiles considering speed change behavior for the safety assessment of signalized intersections.

    Science.gov (United States)

    Iryo-Asano, Miho; Alhajyaseen, Wael K M

    2017-11-01

    Pedestrian safety is one of the most challenging issues in road networks. Understanding how pedestrians maneuver across an intersection is the key to applying countermeasures against traffic crashes. It is known that the behaviors of pedestrians at signalized crosswalks are significantly different from those in ordinary walking spaces, and they are highly influenced by signal indication, potential conflicts with vehicles, and intersection geometries. One of the most important characteristics of pedestrian behavior at crosswalks is the possible sudden speed change while crossing. Such sudden behavioral change may not be expected by conflicting vehicles, which may lead to hazardous situations. This study aims to quantitatively model the sudden speed changes of pedestrians as they cross signalized crosswalks under uncongested conditions. Pedestrian speed profiles are collected from empirical data and speed change events are extracted assuming that the speed profiles are stepwise functions. The occurrence of speed change events is described by a discrete choice model as a function of the necessary walking speed to complete crossing before the red interval ends, current speed, and the presence of turning vehicles in the conflict area. The amount of speed change before and after the event is modeled using regression analysis. A Monte Carlo simulation is applied for the entire speed profile of the pedestrians. The results show that the model can represent the pedestrian travel time distribution more accurately than the constant speed model. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. A IF Signal Precessing System Design Based on Software Radio Platform

    Directory of Open Access Journals (Sweden)

    Zhao Jing

    2018-01-01

    Full Text Available Software radio is a definition of a design thought about how to implement flexible functions by using fixed hardware platform. Any platform based on this is characterized to be universal, standardized, modular, open and highly flexible. Due to some realistic reasons, a software radio platform is hard to be realized. So, most signal processing is operated after mixing. According to software radio requirements, a “FPGA+ADC+DAC” structure is designed. Compared with former processors, this module has broad application prospects with the small size, low power, configurable and programmable feathers. It has multifunction, such as generating IF signals, performing digital down conversion and realizing the synchronous demodulation and the other functions. This module also provides the extended host interface to communicate with upper computers. According to the practical test, take MSK signal for example, if the bit rate is 1Mb/s, bit error rate is lower than 10-6.

  3. A design of a valid signal selecting and position decoding ASIC for PET using silicon photomultipliers

    International Nuclear Information System (INIS)

    Cho, M.; Lim, K.-T.; Kim, J.; Lee, C.; Cho, G.; Kim, H.; Yeom, J.-Y.; Choi, H.

    2017-01-01

    In most cases, a PET system has numerous electrical components and channel circuits and thus it would rather be a bulky product. Also, most existing systems receive analog signals from detectors which make them vulnerable to signal distortions. For these reasons, channel reduction techniques are important. In this work, an ASIC for PET module is being proposed. An ASIC chip for 16 PET detector channels, VSSPDC, has been designed and simulated. The main function of the chip is 16-to-1 channel reduction, i.e., finding the position of only the valid signals, signal timing, and magnitudes in all 16 channels at every recorded event. The ASIC comprises four of 4-channel modules and a 2 nd 4-to-1 router. A single channel module comprises a transimpedance amplifier for the silicon photomultipliers, dual comparators with high and low level references, and a logic circuitry. While the high level reference was used to test the validity of the signal, the low level reference was used for the timing. The 1-channel module of the ASIC produced an energy pulse by time-over-threshold method and it also produced a time pulse with a fixed delayed time. Since the ASIC chip outputs only a few digital pulses and does not require an external clock, it has an advantage over noise properties. The cadence simulation showed the good performance of the chip as designed.

  4. Optimal Signal Design for Mixed Equilibrium Networks with Autonomous and Regular Vehicles

    Directory of Open Access Journals (Sweden)

    Nan Jiang

    2017-01-01

    Full Text Available A signal design problem is studied for efficiently managing autonomous vehicles (AVs and regular vehicles (RVs simultaneously in transportation networks. AVs and RVs move on separate lanes and two types of vehicles share the green times at the same intersections. The signal design problem is formulated as a bilevel program. The lower-level model describes a mixed equilibrium where autonomous vehicles follow the Cournot-Nash (CN principle and RVs follow the user equilibrium (UE principle. In the upper-level model, signal timings are optimized at signalized intersections to allocate appropriate green times to both autonomous and RVs to minimize system travel cost. The sensitivity analysis based method is used to solve the bilevel optimization model. Various signal control strategies are evaluated through numerical examples and some insightful findings are obtained. It was found that the number of phases at intersections should be reduced for the optimal control of the AVs and RVs in the mixed networks. More importantly, incorporating AVs into the transportation network would improve the system performance due to the value of AV technologies in reducing random delays at intersections. Meanwhile, travelers prefer to choose AVs when the networks turn to be congested.

  5. Bridging cognitive screening tests in neurologic disorders: A crosswalk between the short Montreal Cognitive Assessment and Mini-Mental State Examination.

    Science.gov (United States)

    Roalf, David R; Moore, Tyler M; Mechanic-Hamilton, Dawn; Wolk, David A; Arnold, Steven E; Weintraub, Daniel A; Moberg, Paul J

    2017-08-01

    To provide a crosswalk between the recently proposed short Montreal Cognitive Assessment (s-MoCA) and Mini-Mental State Examination (MMSE) within a clinical cohort. A total of 791 participants, with and without neurologic conditions, received both the MMSE and the MoCA at the same visit. s-MoCA scores were calculated and equipercentile equating was used to create a crosswalk between the s-MoCA and MMSE. As expected, s-MoCA scores were highly correlated (Pearson r = 0.82, P < .001) with MMSE scores. s-MoCA scores correctly classified 85% of healthy older adults and 91% of individuals with neurologic conditions that impair cognition. In addition, we provide an easy to use table that enables the conversion of s-MoCA score to MMSE score. The s-MoCA is quick to administer, provides high sensitivity and specificity for cognitive impairment, and now can be compared directly with the MMSE. Copyright © 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  6. A preferential design approach for energy-efficient and robust implantable neural signal processing hardware.

    Science.gov (United States)

    Narasimhan, Seetharam; Chiel, Hillel J; Bhunia, Swarup

    2009-01-01

    For implantable neural interface applications, it is important to compress data and analyze spike patterns across multiple channels in real time. Such a computational task for online neural data processing requires an innovative circuit-architecture level design approach for low-power, robust and area-efficient hardware implementation. Conventional microprocessor or Digital Signal Processing (DSP) chips would dissipate too much power and are too large in size for an implantable system. In this paper, we propose a novel hardware design approach, referred to as "Preferential Design" that exploits the nature of the neural signal processing algorithm to achieve a low-voltage, robust and area-efficient implementation using nanoscale process technology. The basic idea is to isolate the critical components with respect to system performance and design them more conservatively compared to the noncritical ones. This allows aggressive voltage scaling for low power operation while ensuring robustness and area efficiency. We have applied the proposed approach to a neural signal processing algorithm using the Discrete Wavelet Transform (DWT) and observed significant improvement in power and robustness over conventional design.

  7. Design of a Continuous Blood Pressure Measurement System Based on Pulse Wave and ECG Signals.

    Science.gov (United States)

    Li, Jian-Qiang; Li, Rui; Chen, Zhuang-Zhuang; Deng, Gen-Qiang; Wang, Huihui; Mavromoustakis, Constandinos X; Song, Houbing; Ming, Zhong

    2018-01-01

    With increasingly fierce competition for jobs, the pressures on people have risen in recent years, leading to lifestyle and diet disorders that result in significantly higher risks of cardiovascular disease. Hypertension is one of the common chronic cardiovascular diseases; however, mainstream blood pressure measurement devices are relatively heavy. When multiple measurements are required, the user experience and the measurement results may be unsatisfactory. In this paper, we describe the design of a signal collection module that collects pulse waves and electrocardiograph (ECG) signals. The collected signals are input into a signal processing module to filter the noise and amplify the useful physiological signals. Then, we use a wavelet transform to eliminate baseline drift noise and detect the feature points of the pulse waves and ECG signals. We propose the concept of detecting the wave shape associated with an instance, an approach that minimizes the impact of atypical pulse waves on blood pressure measurements. Finally, we propose an improved method for measuring blood pressure based on pulse wave velocity that improves the accuracy of blood pressure measurements by 58%. Moreover, the results meet the american medical instrument promotion association standards, which demonstrate the feasibility of our measurement system.

  8. Decentralized Hierarchical Controller Design for Selective Damping of Inter Area Oscillations Using PMU Signals

    Directory of Open Access Journals (Sweden)

    Ashfaque Ahmed Hashmani

    2011-07-01

    Full Text Available This paper deals with the decentralized hierarchical PSS (Power System Stabilizer controller design to achieve a better damping of specific inter-area oscillations. The two-level decentralized hierarchical structure consists of two PSS controllers. The first level controller is a local PSS controller for each generator to damp local mode in the area where controller is located. This controller uses only local signals as input signals. The local signal comes from the generator at which the controller is located. The secondary level controller is a multivariable decentralized global PSS controller to damp inter-area modes. This controller uses selected suitable wide area PMU (Phasor Measurement Units signals as inputs. The PMU or global signals are taken from network locations where the oscillations are well observable. The global controller uses only those global input signals in which the assigned single inter-area mode is most observable and is located at a generator that is most effective in controlling the assigned mode. The global controller works mainly in a frequency band given by the natural frequency of the assigned mode. The effectiveness of the resulting hierarchical controller is demonstrated through simulation studies conducted on a test power system.

  9. The effects of advanced digital signal processing concepts on VLSIC/VHSIC design

    Science.gov (United States)

    Jankowski, C.

    Implementations of sophisticated mathematical techniques in advanced digital signal processors can significantly improve performance. Future VLSI and VHSI circuit designs must include the practical realization of these algorithms. A structured design approach is described and illustrated with examples from a RNS FIR filter processor development project. The CAE hardware and software required to support tasks of this complexity are also discussed. An EWS is recommended for controlling essential functions such as logic optimization, simulation and verification. The total IC design system is illustrated with the implementation of a new high performance algorithm for computing complex magnitude.

  10. Designing Non-linear Frequency Modulated Signals For Medical Ultrasound Imaging

    DEFF Research Database (Denmark)

    Gran, Fredrik; Jensen, Jørgen Arendt

    2006-01-01

    In this paper a new method for designing non-linear frequency modulated (NLFM) waveforms for ultrasound imaging is proposed. The objective is to control the amplitude spectrum of the designed waveform and still keep a constant transmit amplitude, so that the transmitted energy is maximized....... The signal-to-noise-ratio can in this way be optimized. The waveform design is based on least squares optimization. A desired amplitude spectrum is chosen, hereafter the phase spectrum is chosen, so that the instantaneous frequency takes on the form of a third order polynomial. The finite energy waveform...

  11. On the optimum signal constellation design for high-speed optical transport networks.

    Science.gov (United States)

    Liu, Tao; Djordjevic, Ivan B

    2012-08-27

    In this paper, we first describe an optimum signal constellation design algorithm, which is optimum in MMSE-sense, called MMSE-OSCD, for channel capacity achieving source distribution. Secondly, we introduce a feedback channel capacity inspired optimum signal constellation design (FCC-OSCD) to further improve the performance of MMSE-OSCD, inspired by the fact that feedback channel capacity is higher than that of systems without feedback. The constellations obtained by FCC-OSCD are, however, OSNR dependent. The optimization is jointly performed together with regular quasi-cyclic low-density parity-check (LDPC) code design. Such obtained coded-modulation scheme, in combination with polarization-multiplexing, is suitable as both 400 Gb/s and multi-Tb/s optical transport enabling technology. Using large girth LDPC code, we demonstrate by Monte Carlo simulations that a 32-ary signal constellation, obtained by FCC-OSCD, outperforms previously proposed optimized 32-ary CIPQ signal constellation by 0.8 dB at BER of 10(-7). On the other hand, the LDPC-coded 16-ary FCC-OSCD outperforms 16-QAM by 1.15 dB at the same BER.

  12. 信号交差点の横断歩道における右左折車両ドライバーの譲り合い行動に関する研究

    OpenAIRE

    HASINA, IASMIN

    2016-01-01

    Conflicts between Pedestrians/cyclists and tuning vehicles are very common at signalized intersection. Such conflicts increase the likelihood for a crash to occur. Since a crosswalk is the place designated for pedestrians to cross the road safely, the maneuvering of turning vehicles at crosswalks is characterized by their compliance with the priority rule: in interactions between turning vehicles and pedestrians on a crosswalk, the pedestrians should be allowed to pass first. Accident data re...

  13. Optimal design of RTCs in digital circuit fault self-repair based on global signal optimization

    Institute of Scientific and Technical Information of China (English)

    Zhang Junbin; Cai Jinyan; Meng Yafeng

    2016-01-01

    Since digital circuits have been widely and thoroughly applied in various fields, electronic systems are increasingly more complicated and require greater reliability. Faults may occur in elec-tronic systems in complicated environments. If immediate field repairs are not made on the faults, elec-tronic systems will not run normally, and this will lead to serious losses. The traditional method for improving system reliability based on redundant fault-tolerant technique has been unable to meet the requirements. Therefore, on the basis of (evolvable hardware)-based and (reparation balance technology)-based electronic circuit fault self-repair strategy proposed in our preliminary work, the optimal design of rectification circuits (RTCs) in electronic circuit fault self-repair based on global sig-nal optimization is deeply researched in this paper. First of all, the basic theory of RTC optimal design based on global signal optimization is proposed. Secondly, relevant considerations and suitable ranges are analyzed. Then, the basic flow of RTC optimal design is researched. Eventually, a typical circuit is selected for simulation verification, and detailed simulated analysis is made on five circumstances that occur during RTC evolution. The simulation results prove that compared with the conventional design method based RTC, the global signal optimization design method based RTC is lower in hardware cost, faster in circuit evolution, higher in convergent precision, and higher in circuit evolution success rate. Therefore, the global signal optimization based RTC optimal design method applied in the elec-tronic circuit fault self-repair technology is proven to be feasible, effective, and advantageous.

  14. Pilot Signal Design and Direct Ranging Methods for Radio Localization Using OFDM Systems

    DEFF Research Database (Denmark)

    Jing, Lishuai

    Having accurate localization capability is becoming important for existing and future terrestrial wireless communication systems, in particular for orthogonal frequency-division multiplexing (OFDM) systems, such as WiMAX, wireless local area network, long-term evolution (LTE) and its extension LTE......-Advanced. To obtain accurate position estimates, not only advanced estimation algorithms are needed but also the transmitted signals should be scrutinized. In this dissertation, we investigate how to design OFDM pilot signals and propose and evaluate high accuracy ranging techniques with tractable computational....... For scenarios where the number of path components is unknown and these components are not necessary separable, we propose a direct ranging technique using the received frequency-domain OFDM pilot signals. Compared to conventional (two-step) ranging methods, which estimate intermediate parameters...

  15. A High Precision Position Sensor Design and Its Signal Processing Algorithm for a Maglev Train

    Directory of Open Access Journals (Sweden)

    Wensen Chang

    2012-04-01

    Full Text Available High precision positioning technology for a kind of high speed maglev train with an electromagnetic suspension (EMS system is studied. At first, the basic structure and functions of the position sensor are introduced and some key techniques to enhance the positioning precision are designed. Then, in order to further improve the positioning signal quality and the fault-tolerant ability of the sensor, a new kind of discrete-time tracking differentiator (TD is proposed based on nonlinear optimal control theory. This new TD has good filtering and differentiating performances and a small calculation load. It is suitable for real-time signal processing. The stability, convergence property and frequency characteristics of the TD are studied and analyzed thoroughly. The delay constant of the TD is figured out and an effective time delay compensation algorithm is proposed. Based on the TD technology, a filtering process is introduced in to improve the positioning signal waveform when the sensor is under bad working conditions, and a two-sensor switching algorithm is designed to eliminate the positioning errors caused by the joint gaps of the long stator. The effectiveness and stability of the sensor and its signal processing algorithms are proved by the experiments on a test train during a long-term test run.

  16. A high precision position sensor design and its signal processing algorithm for a maglev train.

    Science.gov (United States)

    Xue, Song; Long, Zhiqiang; He, Ning; Chang, Wensen

    2012-01-01

    High precision positioning technology for a kind of high speed maglev train with an electromagnetic suspension (EMS) system is studied. At first, the basic structure and functions of the position sensor are introduced and some key techniques to enhance the positioning precision are designed. Then, in order to further improve the positioning signal quality and the fault-tolerant ability of the sensor, a new kind of discrete-time tracking differentiator (TD) is proposed based on nonlinear optimal control theory. This new TD has good filtering and differentiating performances and a small calculation load. It is suitable for real-time signal processing. The stability, convergence property and frequency characteristics of the TD are studied and analyzed thoroughly. The delay constant of the TD is figured out and an effective time delay compensation algorithm is proposed. Based on the TD technology, a filtering process is introduced in to improve the positioning signal waveform when the sensor is under bad working conditions, and a two-sensor switching algorithm is designed to eliminate the positioning errors caused by the joint gaps of the long stator. The effectiveness and stability of the sensor and its signal processing algorithms are proved by the experiments on a test train during a long-term test run.

  17. EMPIRICAL STUDY ON USABILITY OF CROSSING SUPPORT SYSTEM FOR VISUALLY DISABLED AT SIGNALIZED INTERSECTION

    Science.gov (United States)

    Suzuki, Koji; Fujita, Motohiro; Matsuura, Kazuma; Fukuzono, Kazuyuki

    This paper evaluates the adjustment process for crossing support system for visually disabled at signalized intersections with the use of pedestrian traffic signals in concert with visible light communication (VLC) technology through outdoor experiments. As for the experiments, we put a blindfold on sighted people by eye mask in order to analyze the behavior of acquired visually disabled. And we used a full-scale crosswalk which is taking into consideration the crossing slope, the bumps at the edge of a crosswalk between the roadway and the sidewalkand crosswalk line. From the results of the survey, it is found that repetitive use of the VLC system decreased the number of lost their bearings completely and ended up standing immobile and reduced the crossing time for each person. On the other hand, it is shown that the performance of our VLC system is nearly equal to the existing support system from the view point of crossing time and the number of standing immobile and we clarified the effect factor for guidance accuracy by the regression analyses. Then we broke test subjects down into patterns by cluster analysis, and explained the walking characteristics for each group as they used the VLC system. In addition, we conducted the additional surveys for the quasi-blind subjects who had difficulty walking by using VLC system and visually impaired users. As a result, it is revealed that guidance accuracy was improved by providing the information about their receiving movement at several points on crosswalk and the habit of their walks for each user.

  18. Design of human controlled 1 DOF right hand exoskeleton using electromyography signal

    Science.gov (United States)

    Azzam, M.; Wijaya, S. K.; Prawito

    2017-07-01

    Exoskeleton in general is a structure that is anatomically designed to be able to accommodate the physical movement of its user and provide additional strength. The use of EMG signal to control a 1 DOF right arm exoskeleton is evaluated in this research. This research aims to achieve optimum control using EMG signal. EMG signal is a variation of voltage that occurs when muscle contracts hence its strong correlation with the user's intention of movement. The RMS values of each EMG signal that originates from bicep and tricep muscle are calculated and processed to determine the direction and speed of rotation of a DC motor that actuates the exoskeleton. The RMS calculation is conducted at various array length that will theoretically affect its accuracy. The difference between those two RMS values is then calculated and interpreted as the intention of flexion or extension movement that will control the DC motor rotational direction. The absolute value of the RMS difference multiplied with a gain factor is used to regulate the duty cycle of a PWM signal that is used to control the rotational speed of the DC motor. To achieve the smallest settling time, array length and gain factor were varied. The test was conducted in two stages, static and dynamic tests. The test result shows a trend where the settling time decreases when array length is shortened and gain is increased. It shows that optimum control can be achieved by selecting the right array length and gain.

  19. Novel textile systems for the continuous monitoring of vital signals: design and characterization.

    Science.gov (United States)

    Trindade, Isabel G; Martins, Frederico; Dias, Rúben; Oliveira, Cristina; Machado da Silva, José

    2015-08-01

    In this article we present a smart textile system for the continuous monitoring of cardiorespiratory signals, produced and integrated with an industrial embroidery unit. The design of a T-shirt system, having embedded textile sensors and interconnects and custom designed circuit for data collection and Bluetooth transmission is presented. The performance of skin-contact textile electrodes, having distinctive electrical characteristics and surface morphologies, was characterized by measurements of signal to noise ratio, under dry and moisture conditions. The influence of the electrodes size and the wear resistance were addressed. Results of an electrocardiogram acquisition with a subject wearing the T-shirt and display on a smartphone are also shown. The presented smart textile systems exhibit good performance and versatility for custom demand production.

  20. A reuse-based framework for the design of analog and mixed-signal ICs

    Science.gov (United States)

    Castro-Lopez, Rafael; Fernandez, Francisco V.; Rodriguez Vazquez, Angel

    2005-06-01

    Despite the spectacular breakthroughs of the semiconductor industry, the ability to design integrated circuits (ICs) under stringent time-to-market (TTM) requirements is lagging behind integration capacity, so far keeping pace with still valid Moore"s Law. The resulting gap is threatening with slowing down such a phenomenal growth. The design community believes that it is only by means of powerful CAD tools and design methodologies - and, possibly, a design paradigm shift - that this design gap can be bridged. In this sense, reuse-based design is seen as a promising solution, and concepts such as IP Block, Virtual Component, and Design Reuse have become commonplace thanks to the significant advances in the digital arena. Unfortunately, the very nature of analog and mixed-signal (AMS) design has hindered a similar level of consensus and development. This paper presents a framework for the reuse-based design of AMS circuits. The framework is founded on three key elements: (1) a CAD-supported hierarchical design flow that facilitates the incorporation of AMS reusable blocks, reduces the overall design time, and expedites the management of increasing AMS design complexity; (2) a complete, clear definition of the AMS reusable block, structured into three separate facets or views: the behavioral, structural, and layout facets, the two first for top-down electrical synthesis and bottom-up verification, the latter used during bottom-up physical synthesis; (3) the design for reusability set of tools, methods, and guidelines that, relying on intensive parameterization as well as on design knowledge capture and encapsulation, allows to produce fully reusable AMS blocks. A case study and a functional silicon prototype demonstrate the validity of the paper"s proposals.

  1. Conceptual design of signal cable feedthrus for an SSC proposed Liquid Argon Calorimeter

    International Nuclear Information System (INIS)

    Pope, W.; Watt, R.; Weidenbach, R.; Fong, M.; Bintinger, D.; Abrams, G.; Unno, Y.

    1991-03-01

    Fast, low noise readout, high channel counts, and physical space, length, and heat leak constraints on signal cables for Liquid Argon Calorimeters (LAC) for SSC Detectors impose stringent requirements on the performance and reliability of its cryogenic feedthrus. We present the design status of a configuration currently under study for the Solenoidal Detector Collaboration's LAC Detector option. The report includes LAr-to-vacuum leak mitigation, warm cable conduction intercept means, and heat leak estimates for a 1900 pin, hermetic feedthru plate design. 12 refs., 4 figs., 2 tabs

  2. Design and Evaluation of Novel Textile Wearable Systems for the Surveillance of Vital Signals

    Directory of Open Access Journals (Sweden)

    Isabel G. Trindade

    2016-09-01

    Full Text Available This article addresses the design, development, and evaluation of T-shirt prototypes that embed novel textile sensors for the capture of cardio and respiratory signals. The sensors are connected through textile interconnects to either an embedded custom-designed data acquisition and transmission unit or to snap fastener terminals for connection to external monitoring devices. The performance of the T-shirt prototype is evaluated in terms of signal-to-noise ratio amplitude and signal interference caused by baseline wander and motion artefacts, through laboratory tests with subjects in standing and walking conditions. Performance tests were also conducted in a hospital environment using a T-shirt prototype connected to a commercial three-channel Holter monitoring device. The textile sensors and interconnects were realized with the assistance of an industrial six-needle digital embroidery tool and their resistance to wear addressed with normalized tests of laundering and abrasion. The performance of these wearable systems is discussed, and pathways and methods for their optimization are highlighted.

  3. Design and Evaluation of Novel Textile Wearable Systems for the Surveillance of Vital Signals.

    Science.gov (United States)

    Trindade, Isabel G; Machado da Silva, José; Miguel, Rui; Pereira, Madalena; Lucas, José; Oliveira, Luís; Valentim, Bruno; Barreto, Jorge; Santos Silva, Manuel

    2016-09-24

    This article addresses the design, development, and evaluation of T-shirt prototypes that embed novel textile sensors for the capture of cardio and respiratory signals. The sensors are connected through textile interconnects to either an embedded custom-designed data acquisition and transmission unit or to snap fastener terminals for connection to external monitoring devices. The performance of the T-shirt prototype is evaluated in terms of signal-to-noise ratio amplitude and signal interference caused by baseline wander and motion artefacts, through laboratory tests with subjects in standing and walking conditions. Performance tests were also conducted in a hospital environment using a T-shirt prototype connected to a commercial three-channel Holter monitoring device. The textile sensors and interconnects were realized with the assistance of an industrial six-needle digital embroidery tool and their resistance to wear addressed with normalized tests of laundering and abrasion. The performance of these wearable systems is discussed, and pathways and methods for their optimization are highlighted.

  4. The Design of Wireless Data Acquisition and Remote Transmission Interface in Micro-seismic Signals

    Directory of Open Access Journals (Sweden)

    Huan-Huan BIAN

    2014-02-01

    Full Text Available The micro-seismic signal acquisition and transmission is an important key part in geological prospecting. This paper describes a bran-new solution of micro-seismic signal acquisition and remote transmission using Zigbee technique and wireless data transmission technique. The hardware such as front-end data acquisition interface made up by Zigbee wireless networking technique, remote data transmission solution composed of general packet radio service (or GPRS for short technique and interface between Zigbee and GPRS is designed in detail. Meanwhile the corresponding software of the system is given out. The solution solves the numerous practical problems nagged by complex and terrible environment faced using micro-seismic prospecting. The experimental results demonstrate that the method using Zigbee wireless network communication technique GPRS wireless packet switching technique is efficient, reliable and flexible.

  5. Synchronization of a class of chaotic signals via robust observer design

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Lopez, Ricardo [Departamento de Energia, Universidad Autonoma Metropolitana - Azcapotzalco, San Pablo 180, Reynosa-Tamaulipas, Azcapotzalco 02200, Mexico, D.F. (Mexico)], E-mail: raguilar@correo.azc.uam.mx; Martinez-Guerra, Rafael [Departamento de Energia, Universidad Autonoma Metropolitana - Azcapotzalco, San Pablo 180, Reynosa-Tamaulipas, Azcapotzalco 02200, Mexico, D.F. (Mexico); Departamento de Control Automatico, CINVESTAV IPN, Apartado Postal 14-740, Mexico, D.F. C.P. 07360 (Mexico)], E-mail: rguerra@ctrl.cinvestav.mx

    2008-07-15

    In this paper the signal synchronization of a class of chaotic systems based on robust observer design is tackled. The task is the synchronization of the signals generated by two Chen oscillators with different initial condition. The proposed observer is robust against model uncertainties and noisy output measurements. An alternative system representation is proposed to transform the measured disturbance onto system disturbance, which leads a more adequate observer structure. The proposed methodology contains an uncertainty estimator based on the predictive contribution to infer the unobservable uncertainties and corrective contribution to estimate the observable uncertainties; which provides robustness against noisy measurements and model uncertainties. Convergence analysis of the proposed estimation methodology is realized, analyzing the dynamic equation of the estimation error, where asymptotic convergence is shown. Numerical experiments illustrate the good performance of the proposed methodology.

  6. Synchronization of a class of chaotic signals via robust observer design

    International Nuclear Information System (INIS)

    Aguilar-Lopez, Ricardo; Martinez-Guerra, Rafael

    2008-01-01

    In this paper the signal synchronization of a class of chaotic systems based on robust observer design is tackled. The task is the synchronization of the signals generated by two Chen oscillators with different initial condition. The proposed observer is robust against model uncertainties and noisy output measurements. An alternative system representation is proposed to transform the measured disturbance onto system disturbance, which leads a more adequate observer structure. The proposed methodology contains an uncertainty estimator based on the predictive contribution to infer the unobservable uncertainties and corrective contribution to estimate the observable uncertainties; which provides robustness against noisy measurements and model uncertainties. Convergence analysis of the proposed estimation methodology is realized, analyzing the dynamic equation of the estimation error, where asymptotic convergence is shown. Numerical experiments illustrate the good performance of the proposed methodology

  7. Use of modulated excitation signals in ultrasound. Part II: Design and performance for medical imaging applications

    DEFF Research Database (Denmark)

    Misaridis, Thanassis; Jensen, Jørgen Arendt

    2005-01-01

    ultrasound presents design methods of linear FM signals and mismatched filters, in order to meet the higher demands on resolution in ultrasound imaging. It is shown that for the small time-bandwidth (TB) products available in ultrasound, the rectangular spectrum approximation is not valid, which reduces....... The method is evaluated first for resolution performance and axial sidelobes through simulations with the program Field II. A coded excitation ultrasound imaging system based on a commercial scanner and a 4 MHz probe driven by coded sequences is presented and used for the clinical evaluation of the coded...... excitation/compression scheme. The clinical images show a significant improvement in penetration depth and contrast, while they preserve both axial and lateral resolution. At the maximum acquisition depth of 15 cm, there is an improvement of more than 10 dB in the signal-to-noise ratio of the images...

  8. MIMO Radar Transceiver Design for High Signal-to-Interference-Plus-Noise Ratio

    KAUST Repository

    Lipor, John

    2013-05-12

    Multiple-input multiple-output (MIMO) radar employs orthogonal or partially correlated transmit signals to achieve performance benefits over its phased-array counterpart. It has been shown that MIMO radar can achieve greater spatial resolution, improved signal-to-noise ratio (SNR) and target localization, and greater clutter resolution using space-time adaptive processing (STAP). This thesis explores various methods to improve the signal-to-interference-plus-noise ratio (SINR) via transmit and receive beamforming. In MIMO radar settings, it is often desirable to transmit power only to a given location or set of locations defined by a beampattern. Current methods involve a two- step process of designing the transmit covariance matrix R via iterative solutions and then using R to generate waveforms that fulfill practical constraints such as having a constant-envelope or drawing from a finite alphabet. In this document, a closed- form method to design R is proposed that utilizes the discrete Fourier transform (DFT) coefficients and Toeplitz matrices. The resulting covariance matrix fulfills the practical constraints such as positive semidefiniteness and the uniform elemental power constraint and provides performance similar to that of iterative methods, which require a much greater computation time. Next, a transmit architecture is presented 
that exploits the orthogonality of frequencies at discrete DFT values to transmit a sum of orthogonal signals from each antenna. The resulting waveforms provide a lower mean-square error than current methods at a much lower computational cost, and a simulated detection scenario demonstrates the performance advantages achieved. It is also desirable to receive signal power only from a given set of directions defined by a beampattern. In a later chapter of this document, the problem of receive beampattern matching is formulated and three solutions to this problem are demonstrated. We show that partitioning the received data vector

  9. A SystemC-Based Design Methodology for Digital Signal Processing Systems

    Directory of Open Access Journals (Sweden)

    Christian Haubelt

    2007-03-01

    Full Text Available Digital signal processing algorithms are of big importance in many embedded systems. Due to complexity reasons and due to the restrictions imposed on the implementations, new design methodologies are needed. In this paper, we present a SystemC-based solution supporting automatic design space exploration, automatic performance evaluation, as well as automatic system generation for mixed hardware/software solutions mapped onto FPGA-based platforms. Our proposed hardware/software codesign approach is based on a SystemC-based library called SysteMoC that permits the expression of different models of computation well known in the domain of digital signal processing. It combines the advantages of executability and analyzability of many important models of computation that can be expressed in SysteMoC. We will use the example of an MPEG-4 decoder throughout this paper to introduce our novel methodology. Results from a five-dimensional design space exploration and from automatically mapping parts of the MPEG-4 decoder onto a Xilinx FPGA platform will demonstrate the effectiveness of our approach.

  10. Design of pulse oximetry signal based on personal computer for detection oxygen saturation

    International Nuclear Information System (INIS)

    Umi Salamah; Margi Sasono

    2015-01-01

    The lack or excess of oxygen in the blood will cause healthy and body system disorder. At certain level, the disease can lead to death. For that reason, the information about oxygen saturation in blood becomes important to be identified. One of the devices used to monitor the blood oxygen saturation is pulse oximetry. This research attempt to designed Pulse Oximetry based on personal computer using red LED and infrared as its light source, while the light sensor using photodiode. The designed Pulse Oximetry is a non-invasive instrumentation which LED drivers is placed on the fingertips. The LED light goes through the finger will be a signal that is fed to the photodiode and will be converted into digital signals by ADC (Analog to Digital Converter) and will be processed further by a personal computer to display the pulse oximetry graphics. This study uses Delphi 7, Microsoft Excel, and Mt Lab as its software.This designed pulse oximetry has been tested in two peoples: sample A, male 38 years; and sample B, a woman 23 years old. Oxygen saturation of sample A is 80.75, while the sample B is 90.75. (author)

  11. Design, development and implementation of the IR signaling techniques for monitoring ambient and body temperature

    International Nuclear Information System (INIS)

    Baqai, A.

    2014-01-01

    Healthcare systems such as hospitals, homecare, telemedicine, and physical rehabilitation are expected to be revolutionized by WBAN (Wireless Body Area Networks). This research work aims to investigate, design, optimize, and demonstrate the applications of IR (Infra-Red) communication systems in WBAN. It is aimed to establish a prototype WBAN system capable of measuring Ambient and Body Temperature using LM35 as temperature sensor and transmitting and receiving the data using optical signals. The corresponding technical challenges that have to be faced are also discussed in this paper. Investigations are carried out to efficiently design the hardware using low-cost and low power optical transceivers. The experimental results reveal the successful transmission and reception of Ambient and Body Temperatures over short ranges i.e. up to 3-4 meters. A simple IR transceiver with an LED (Light Emitting Diodes), TV remote control IC and Arduino microcontroller is designed to perform the transmission with sufficient accuracy and ease. Experiments are also performed to avoid interference from other sources like AC and TV remote control signals by implementing IR tags. (author)

  12. Design, development and implementation of the IR signaling techniques for monitoring ambient and body temperature

    Energy Technology Data Exchange (ETDEWEB)

    Baqai, A. [Mehran Univ. of Engineering and Technology, Jamshoro (Pakistan). Dept. of Information and Communication Technology

    2014-07-15

    Healthcare systems such as hospitals, homecare, telemedicine, and physical rehabilitation are expected to be revolutionized by WBAN (Wireless Body Area Networks). This research work aims to investigate, design, optimize, and demonstrate the applications of IR (Infra-Red) communication systems in WBAN. It is aimed to establish a prototype WBAN system capable of measuring Ambient and Body Temperature using LM35 as temperature sensor and transmitting and receiving the data using optical signals. The corresponding technical challenges that have to be faced are also discussed in this paper. Investigations are carried out to efficiently design the hardware using low-cost and low power optical transceivers. The experimental results reveal the successful transmission and reception of Ambient and Body Temperatures over short ranges i.e. up to 3-4 meters. A simple IR transceiver with an LED (Light Emitting Diodes), TV remote control IC and Arduino microcontroller is designed to perform the transmission with sufficient accuracy and ease. Experiments are also performed to avoid interference from other sources like AC and TV remote control signals by implementing IR tags. (author)

  13. Hardware Design and Implementation of a Wavelet De-Noising Procedure for Medical Signal Preprocessing

    Directory of Open Access Journals (Sweden)

    Szi-Wen Chen

    2015-10-01

    Full Text Available In this paper, a discrete wavelet transform (DWT based de-noising with its applications into the noise reduction for medical signal preprocessing is introduced. This work focuses on the hardware realization of a real-time wavelet de-noising procedure. The proposed de-noising circuit mainly consists of three modules: a DWT, a thresholding, and an inverse DWT (IDWT modular circuits. We also proposed a novel adaptive thresholding scheme and incorporated it into our wavelet de-noising procedure. Performance was then evaluated on both the architectural designs of the software and. In addition, the de-noising circuit was also implemented by downloading the Verilog codes to a field programmable gate array (FPGA based platform so that its ability in noise reduction may be further validated in actual practice. Simulation experiment results produced by applying a set of simulated noise-contaminated electrocardiogram (ECG signals into the de-noising circuit showed that the circuit could not only desirably meet the requirement of real-time processing, but also achieve satisfactory performance for noise reduction, while the sharp features of the ECG signals can be well preserved. The proposed de-noising circuit was further synthesized using the Synopsys Design Compiler with an Artisan Taiwan Semiconductor Manufacturing Company (TSMC, Hsinchu, Taiwan 40 nm standard cell library. The integrated circuit (IC synthesis simulation results showed that the proposed design can achieve a clock frequency of 200 MHz and the power consumption was only 17.4 mW, when operated at 200 MHz.

  14. Hardware design and implementation of a wavelet de-noising procedure for medical signal preprocessing.

    Science.gov (United States)

    Chen, Szi-Wen; Chen, Yuan-Ho

    2015-10-16

    In this paper, a discrete wavelet transform (DWT) based de-noising with its applications into the noise reduction for medical signal preprocessing is introduced. This work focuses on the hardware realization of a real-time wavelet de-noising procedure. The proposed de-noising circuit mainly consists of three modules: a DWT, a thresholding, and an inverse DWT (IDWT) modular circuits. We also proposed a novel adaptive thresholding scheme and incorporated it into our wavelet de-noising procedure. Performance was then evaluated on both the architectural designs of the software and. In addition, the de-noising circuit was also implemented by downloading the Verilog codes to a field programmable gate array (FPGA) based platform so that its ability in noise reduction may be further validated in actual practice. Simulation experiment results produced by applying a set of simulated noise-contaminated electrocardiogram (ECG) signals into the de-noising circuit showed that the circuit could not only desirably meet the requirement of real-time processing, but also achieve satisfactory performance for noise reduction, while the sharp features of the ECG signals can be well preserved. The proposed de-noising circuit was further synthesized using the Synopsys Design Compiler with an Artisan Taiwan Semiconductor Manufacturing Company (TSMC, Hsinchu, Taiwan) 40 nm standard cell library. The integrated circuit (IC) synthesis simulation results showed that the proposed design can achieve a clock frequency of 200 MHz and the power consumption was only 17.4 mW, when operated at 200 MHz.

  15. Design of Accelerated Reliability Test for CNC Motorized Spindle Based on Vibration Signal

    Directory of Open Access Journals (Sweden)

    Chen Chao

    2016-01-01

    Full Text Available Motorized spindle is the key functional component of CNC machining centers which is a mechatronics system with long life and high reliability. The reliability test cycle of motorized spindle is too long and infeasible. This paper proposes a new accelerated test for reliability evaluation of motorized spindle. By field reliability test, authors collect and calculate the load data including rotational speed, cutting force and torque. Load spectrum distribution law is analyzed. And authors design a test platform to apply the load spectrum. A new method to define the fuzzy acceleration factor based on the vibration signal is proposed. Then the whole test plan of accelerated reliability test is done.

  16. Design of microcontroller-based EMG and the analysis of EMG signals.

    Science.gov (United States)

    Güler, Nihal Fatma; Hardalaç, Firat

    2002-04-01

    In this work, a microcontroller-based EMG designed and tested on 40 patients. When the patients are in rest, the fast Fourier transform (FFT) analysis was applied to EMG signals recorded from right leg peroneal region. The histograms are constructed from the results of the FFT analysis. The analysis results shows that the amplitude of fibrillation potential of the muscle fiber of 30 patients measured from peroneal region is low and the duration is short. This is the reason why the motor nerves degenerated and 10 patients were found to be healthy.

  17. The design of photoelectric signal processing system for a nuclear magnetic resonance gyroscope based on FPGA

    Science.gov (United States)

    Zhang, Xian; Zhou, Binquan; Li, Hong; Zhao, Xinghua; Mu, Weiwei; Wu, Wenfeng

    2017-10-01

    Navigation technology is crucial to the national defense and military, which can realize the measurement of orientation, positioning, attitude and speed for moving object. Inertial navigation is not only autonomous, real-time, continuous, hidden, undisturbed but also no time-limited and environment-limited. The gyroscope is the core component of the inertial navigation system, whose precision and size are the bottleneck of the performance. However, nuclear magnetic resonance gyroscope is characteristic of the advantage of high precision and small size. Nuclear magnetic resonance gyroscope can meet the urgent needs of high-tech weapons and equipment development of new generation. This paper mainly designs a set of photoelectric signal processing system for nuclear magnetic resonance gyroscope based on FPGA, which process and control the information of detecting laser .The photoelectric signal with high frequency carrier is demodulated by in-phase and quadrature demodulation method. Finally, the processing system of photoelectric signal can compensate the residual magnetism of the shielding barrel and provide the information of nuclear magnetic resonance gyroscope angular velocity.

  18. Design and evaluation of online arithmetic for signal processing applications on FPGAs

    Science.gov (United States)

    Galli, Reto; Tenca, Alexandre F.

    2001-11-01

    This paper shows the design and the evaluation of on-line arithmetic modules for the most common operators used in DSP applications, using FPGAs as the target technology. The designs are highly optimized for the target technology and the common range of precision in DSP. The results are based on experimental data collected using CAD tools. All designs are synthesized for the same type of devices (Xilinx XC4000) for comparison, avoiding rough estimates of the system performance, and generating a more reliable and detailed comparison of on-line signal processing solutions with other state of the art approaches, such as distributed arithmetic. We show that on-line designs have a hard stand for basic DSP applications that use only addition and multiplication. However, we also show that on-line designs are able to overtake other approaches as the applications become more sophisticated, e.g. when data dependencies exist, or when non constant multiplicands restrict the use of other approaches.

  19. Optimal experimental design in an epidermal growth factor receptor signalling and down-regulation model.

    Science.gov (United States)

    Casey, F P; Baird, D; Feng, Q; Gutenkunst, R N; Waterfall, J J; Myers, C R; Brown, K S; Cerione, R A; Sethna, J P

    2007-05-01

    We apply the methods of optimal experimental design to a differential equation model for epidermal growth factor receptor signalling, trafficking and down-regulation. The model incorporates the role of a recently discovered protein complex made up of the E3 ubiquitin ligase, Cbl, the guanine exchange factor (GEF), Cool-1 (beta -Pix) and the Rho family G protein Cdc42. The complex has been suggested to be important in disrupting receptor down-regulation. We demonstrate that the model interactions can accurately reproduce the experimental observations, that they can be used to make predictions with accompanying uncertainties, and that we can apply ideas of optimal experimental design to suggest new experiments that reduce the uncertainty on unmeasurable components of the system.

  20. Custom chipset and compact module design for a 75–110 GHz laboratory signal source

    International Nuclear Information System (INIS)

    Morgan, Matthew A; Boyd, Tod A; Castro, Jason J

    2016-01-01

    We report on the development and characterization of a compact, full-waveguide bandwidth (WR-10) signal source for general-purpose testing of mm-wave components. The monolithic microwave integrated circuit (MMIC) based multichip module is designed for compactness and ease-of-use, especially in size-constrained test sets such as a wafer probe station. It takes as input a cm-wave continuous-wave (CW) reference and provides a factor of three frequency multiplication as well as amplification, output power adjustment, and in situ output power monitoring. It utilizes a number of custom MMIC chips such as a Schottky-diode limiter and a broadband mm-wave detector, both designed explicitly for this module, as well as custom millimeter-wave multipliers and amplifiers reported in previous papers. (paper)

  1. Conceptual design of a versatile radiation tolerant integrated signal conditioning circuit for resistive sensors

    Energy Technology Data Exchange (ETDEWEB)

    Leroux, P. [Katholieke Hogeschool Kempen, Kleinhoefstraat 4, B-2440 Geel (Belgium); Katholieke Universiteit Leuven, Dept. ESAT-MICAS, Kasteelpark Arenberg 10, B-3001 Heverlee (Belgium); SCK-CEN, Belgian Nuclear Research Centre, Boeretang 200, B-2400 Mol (Belgium); Sterckx, J. [Katholieke Hogeschool Kempen, Kleinhoefstraat 4, B-2440 Geel (Belgium); Van Uffelen, M.; Damiani, C. [Fusion 4 Energy, Ed. B3, c/Josep, no 2, Torres Diagonal Litoral, 08019 Barcelona (Spain)

    2011-07-01

    This paper presents the design of a radiation tolerant configurable discrete time CMOS signal conditioning circuit for use with resistive sensors like strain gauge pressure sensors. The circuit is intended to be used for remote handling in harsh environments in the International Thermonuclear Experimental fusion Reactor (ITER). The design features a 5 V differential preamplifier using a Correlated Double Sampling (CDS) architecture at a sample rate of 20 kHz and a 24 V discrete time post amplifier. The gain is digitally controllable between 27 and 400 in the preamplifier and between 1 and 8 in the post amplifier. The nominal input referred noise voltage is only 8.5 {mu}V while consuming only 1 mW. The circuit has a simulated radiation tolerance of more than 1 MGy. (authors)

  2. An integrated framework for high level design of high performance signal processing circuits on FPGAs

    Science.gov (United States)

    Benkrid, K.; Belkacemi, S.; Sukhsawas, S.

    2005-06-01

    This paper proposes an integrated framework for the high level design of high performance signal processing algorithms' implementations on FPGAs. The framework emerged from a constant need to rapidly implement increasingly complicated algorithms on FPGAs while maintaining the high performance needed in many real time digital signal processing applications. This is particularly important for application developers who often rely on iterative and interactive development methodologies. The central idea behind the proposed framework is to dynamically integrate high performance structural hardware description languages with higher level hardware languages in other to help satisfy the dual requirement of high level design and high performance implementation. The paper illustrates this by integrating two environments: Celoxica's Handel-C language, and HIDE, a structural hardware environment developed at the Queen's University of Belfast. On the one hand, Handel-C has been proven to be very useful in the rapid design and prototyping of FPGA circuits, especially control intensive ones. On the other hand, HIDE, has been used extensively, and successfully, in the generation of highly optimised parameterisable FPGA cores. In this paper, this is illustrated in the construction of a scalable and fully parameterisable core for image algebra's five core neighbourhood operations, where fully floorplanned efficient FPGA configurations, in the form of EDIF netlists, are generated automatically for instances of the core. In the proposed combined framework, highly optimised data paths are invoked dynamically from within Handel-C, and are synthesized using HIDE. Although the idea might seem simple prima facie, it could have serious implications on the design of future generations of hardware description languages.

  3. Design, development and test of the gearbox condition monitoring system using sound signal processing

    Directory of Open Access Journals (Sweden)

    M Zamani

    2016-09-01

    Full Text Available Introduction One of the ways used for minimizing the cost of maintenance and repairs of rotating industrial equipment is condition monitoring using acoustic analysis. One of the most important problems which always have been under consideration in industrial equipment application is confidence possibility. Each dynamic, electrical, hydraulic or thermal system has certain characteristics which show the normal condition of the machine during function. Any changes of the characteristics can be a signal of a problem in the machine. The aim of condition monitoring is system condition determination using measurements of the signals of characteristics and using this information for system impairment prognostication. There are a lot of ways for condition monitoring of different systems, but sound analysis is accepted and used extensively as a method for condition investigation of rotating machines. The aim of this research is the design and construction of considered gearbox and using of obtaining data in frequency and time spectrum in order to analyze the sound and diagnosis. Materials and Methods This research was conducted at the department of mechanical biosystem workshop at Aboureihan College at Tehran University in February 15th.2015. In this research, in order to investigate the trend of diagnosis and gearbox condition, a system was designed and then constructed. The sound of correct and damaged gearbox was investigated by audiometer and stored in computer for data analysis. Sound measurement was done in three pinions speed of 749, 1050 and 1496 rpm and for correct gearboxes, damage of the fracture of a tooth and a tooth wear. Gearbox design and construction: In order to conduct the research, a gearbox with simple gearwheels was designed according to current needs. Then mentioned gearbox and its accessories were modeled in CATIA V5-R20 software and then the system was constructed. Gearbox is a machine that is used for mechanical power transition

  4. Performance bounds on micro-Doppler estimation and adaptive waveform design using OFDM signals

    Science.gov (United States)

    Sen, Satyabrata; Barhen, Jacob; Glover, Charles W.

    2014-05-01

    We analyze the performance of a wideband orthogonal frequency division multiplexing (OFDM) signal in estimating the micro-Doppler frequency of a target having multiple rotating scatterers (e.g., rotor blades of a helicopter, propellers of a submarine). The presence of rotating scatterers introduces Doppler frequency modulation in the received signal by generating sidebands about the transmitted frequencies. This is called the micro-Doppler effects. The use of a frequency-diverse OFDM signal in this context enables us to independently analyze the micro-Doppler characteristics with respect to a set of orthogonal subcarrier frequencies. Therefore, to characterize the accuracy of micro-Doppler frequency estimation, we compute the Craḿer-Rao Bound (CRB) on the angular-velocity estimate of the target while considering the scatterer responses as deterministic but unknown nuisance parameters. Additionally, to improve the accuracy of the estimation procedure, we formulate and solve an optimization problem by minimizing the CRB on the angular-velocity estimate with respect to the transmitting OFDM spectral coefficients. We present several numerical examples to demonstrate the CRB variations at different values of the signal-to-noise ratio (SNR) and the number of OFDM subcarriers. The CRB values not only decrease with the increase in the SNR values, but also reduce as we increase the number of subcarriers implying the significance of frequency-diverse OFDM waveforms. The improvement in estimation accuracy due to the adaptive waveform design is also numerically analyzed. Interestingly, we find that the relative decrease in the CRBs on the angular-velocity estimate is more pronounced for larger number of OFDM subcarriers.

  5. Cell surface receptors for signal transduction and ligand transport: a design principles study.

    Directory of Open Access Journals (Sweden)

    Harish Shankaran

    2007-06-01

    Full Text Available Receptors constitute the interface of cells to their external environment. These molecules bind specific ligands involved in multiple processes, such as signal transduction and nutrient transport. Although a variety of cell surface receptors undergo endocytosis, the systems-level design principles that govern the evolution of receptor trafficking dynamics are far from fully understood. We have constructed a generalized mathematical model of receptor-ligand binding and internalization to understand how receptor internalization dynamics encodes receptor function and regulation. A given signaling or transport receptor system represents a particular implementation of this module with a specific set of kinetic parameters. Parametric analysis of the response of receptor systems to ligand inputs reveals that receptor systems can be characterized as being: i avidity-controlled where the response control depends primarily on the extracellular ligand capture efficiency, ii consumption-controlled where the ability to internalize surface-bound ligand is the primary control parameter, and iii dual-sensitivity where both the avidity and consumption parameters are important. We show that the transferrin and low-density lipoprotein receptors are avidity-controlled, the vitellogenin receptor is consumption-controlled, and the epidermal growth factor receptor is a dual-sensitivity receptor. Significantly, we show that ligand-induced endocytosis is a mechanism to enhance the accuracy of signaling receptors rather than merely serving to attenuate signaling. Our analysis reveals that the location of a receptor system in the avidity-consumption parameter space can be used to understand both its function and its regulation.

  6. Performance Bounds on Micro-Doppler Estimation and Adaptive Waveform Design Using OFDM Signals

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Satyabrata [ORNL; Barhen, Jacob [ORNL; Glover, Charles Wayne [ORNL

    2014-01-01

    We analyze the performance of a wideband orthogonal frequency division multiplexing (OFDM) signal in estimating the micro-Doppler frequency of a target having multiple rotating scatterers (e.g., rotor blades of a helicopter, propellers of a submarine). The presence of rotating scatterers introduces Doppler frequency modulation in the received signal by generating sidebands about the transmitted frequencies. This is called the micro-Doppler effects. The use of a frequency-diverse OFDM signal in this context enables us to independently analyze the micro-Doppler characteristics with respect to a set of orthogonal subcarrier frequencies. Therefore, to characterize the accuracy of micro-Doppler frequency estimation, we compute the Cram er-Rao Bound (CRB) on the angular-velocity estimate of the target while considering the scatterer responses as deterministic but unknown nuisance parameters. Additionally, to improve the accuracy of the estimation procedure, we formulate and solve an optimization problem by minimizing the CRB on the angular-velocity estimate with respect to the transmitting OFDM spectral coefficients. We present several numerical examples to demonstrate the CRB variations at different values of the signal-to-noise ratio (SNR) and the number of OFDM subcarriers. The CRB values not only decrease with the increase in the SNR values, but also reduce as we increase the number of subcarriers implying the significance of frequency-diverse OFDM waveforms. The improvement in estimation accuracy due to the adaptive waveform design is also numerically analyzed. Interestingly, we find that the relative decrease in the CRBs on the angular-velocity estimate is more pronounced for larger number of OFDM subcarriers.

  7. Design Implementation and Testing of a VLSI High Performance ASIC for Extracting the Phase of a Complex Signal

    National Research Council Canada - National Science Library

    Altmeyer, Ronald

    2002-01-01

    This thesis documents the research, circuit design, and simulation testing of a VLSI ASIC which extracts phase angle information from a complex sampled signal using the arctangent relationship: (phi=tan/-1 (Q/1...

  8. Small-Signal Modeling, Stability Analysis and Design Optimization of Single-Phase Delay-Based PLLs

    DEFF Research Database (Denmark)

    Golestan, Saeed; Guerrero, Josep M.; Vidal, Ana

    2016-01-01

    Generally speaking, designing single-phase phaselocked loops (PLLs) is more complicated than three-phase ones, as their implementation often involves the generation of a fictitious orthogonal signal for the frame transformation. In recent years, many approaches to generate the orthogonal signal...... these issues and explore new methods to enhance their performance. The stability analysis, control design guidelines and performance comparison with the state-of-the-art PLLs are presented as well....

  9. Design of complete software GPS signal simulator with low complexity and precise multipath channel model

    Directory of Open Access Journals (Sweden)

    G. Arul Elango

    2016-09-01

    Full Text Available The need for GPS data simulators have become important due to the tremendous growth in the design of versatile GPS receivers. Commercial hardware and software based GPS simulators are expensive and time consuming. In this work, a low cost simple novel GPS L1 signal simulator is designed for testing and evaluating the performance of software GPS receiver in a laboratory environment. A typical real time paradigm, similar to actual satellite derived GPS signal is created on a computer generated scenario. In this paper, a GPS software simulator is proposed that may offer a lot of analysis and testing flexibility to the researchers and developers as it is totally software based primarily running on a laptop/personal computer without the requirement of any hardware. The proposed GPS simulator allows provision for re-configurability and test repeatability and is developed in VC++ platform to minimize the simulation time. It also incorporates Rayleigh multipath channel fading model under non-line of sight (NLOS conditions. In this work, to efficiently design the simulator, several Rayleigh fading models viz. Inverse Discrete Fourier Transform (IDFT, Filtering White Gaussian Noise (FWFN and modified Sum of Sinusoidal (SOS simulators are tested and compared in terms of accuracy of its first and second order statistical metrics, execution time and the later one is found to be as the best appropriate Rayleigh multipath model suitable for incorporating with GPS simulator. The fading model written in ‘MATLAB’ engine has been linked with software GPS simulator module enable to test GPS receiver’s functionality in different fading environments.

  10. Designed modulation of sex steroid signaling inhibits telomerase activity and proliferation of human prostate cancer cells

    International Nuclear Information System (INIS)

    Verma, Vikas; Sharma, Vikas; Singh, Vishal; Sharma, Siddharth; Bishnoi, Ajay Kumar; Chandra, Vishal; Maikhuri, J.P.; Dwivedi, Anila; Kumar, Atul; Gupta, Gopal

    2014-01-01

    The predominant estrogen-receptor (ER)-β signaling in normal prostate is countered by increased ER-α signaling in prostate cancer (CaP), which in association with androgen-receptor (AR) signaling results in pathogenesis of the disease. However CaP treatments mostly target AR signaling which is initially effective but eventually leads to androgen resistance, hence simultaneous targeting of ERs has been proposed. A novel series of molecules were designed with multiple sex-steroid receptor modulating capabilities by coalescing the pharmacophores of known anti-CaP molecules that act via modulation of ER(α/β) and/or AR, viz. 3,3′diindolylmethane (DIM), mifepristone, toremifene, tamoxifen and raloxifene. N,N-diethyl-4-((2-(4-methoxyphenyl)-1H-indol-3-yl)methyl) aniline (DIMA) was identified as the most promising structure of this new series. DIMA increased annexin-V labelling, cell-cycle arrest and caspase-3 activity, and decreased expression of AR and prostate specific antigen in LNCaP cells, in vitro. Concurrently, DIMA increased ER-β, p21 and p27 protein levels in LNCaP cells and exhibited ∼ 5 times more selective binding for ER-β than ER-α, in comparison to raloxifene. DIMA exhibited a dose-dependent ER-β agonism and ER-α antagonism in classical gene reporter assay and decreased hTERT (catalytic subunit of telomerase) transcript levels in LNCaP at 3.0 μM (P < 0.05). DIMA also dose-dependently decreased telomerase enzyme activity in prostate cancer cells. It is thus concluded that DIMA acts as a multi-steroid receptor modulator and effectively inhibits proliferation of prostate cancer cells through ER-β mediated telomerase inhibition, by countering actions of ER-α and AR. Its unique molecular design can serve as a lead structure for generation of potent agents against endocrine malignancies like the CaP

  11. Designed modulation of sex steroid signaling inhibits telomerase activity and proliferation of human prostate cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Verma, Vikas; Sharma, Vikas; Singh, Vishal [Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow 226 031 (India); Sharma, Siddharth; Bishnoi, Ajay Kumar [Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow 226 031 (India); Chandra, Vishal; Maikhuri, J.P.; Dwivedi, Anila [Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow 226 031 (India); Kumar, Atul [Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow 226 031 (India); Gupta, Gopal, E-mail: g_gupta@cdri.res.in [Division of Endocrinology, CSIR-Central Drug Research Institute, Lucknow 226 031 (India)

    2014-10-15

    The predominant estrogen-receptor (ER)-β signaling in normal prostate is countered by increased ER-α signaling in prostate cancer (CaP), which in association with androgen-receptor (AR) signaling results in pathogenesis of the disease. However CaP treatments mostly target AR signaling which is initially effective but eventually leads to androgen resistance, hence simultaneous targeting of ERs has been proposed. A novel series of molecules were designed with multiple sex-steroid receptor modulating capabilities by coalescing the pharmacophores of known anti-CaP molecules that act via modulation of ER(α/β) and/or AR, viz. 3,3′diindolylmethane (DIM), mifepristone, toremifene, tamoxifen and raloxifene. N,N-diethyl-4-((2-(4-methoxyphenyl)-1H-indol-3-yl)methyl) aniline (DIMA) was identified as the most promising structure of this new series. DIMA increased annexin-V labelling, cell-cycle arrest and caspase-3 activity, and decreased expression of AR and prostate specific antigen in LNCaP cells, in vitro. Concurrently, DIMA increased ER-β, p21 and p27 protein levels in LNCaP cells and exhibited ∼ 5 times more selective binding for ER-β than ER-α, in comparison to raloxifene. DIMA exhibited a dose-dependent ER-β agonism and ER-α antagonism in classical gene reporter assay and decreased hTERT (catalytic subunit of telomerase) transcript levels in LNCaP at 3.0 μM (P < 0.05). DIMA also dose-dependently decreased telomerase enzyme activity in prostate cancer cells. It is thus concluded that DIMA acts as a multi-steroid receptor modulator and effectively inhibits proliferation of prostate cancer cells through ER-β mediated telomerase inhibition, by countering actions of ER-α and AR. Its unique molecular design can serve as a lead structure for generation of potent agents against endocrine malignancies like the CaP.

  12. Tests of variable-band multilayers designed for investigating optimal signal-to-noise vs artifact signal ratios in Dual-Energy Digital Subtraction Angiography (DDSA) imaging systems

    International Nuclear Information System (INIS)

    Boyers, D.; Ho, A.; Li, Q.; Piestrup, M.; Rice, M.; Tatchyn, R.

    1993-08-01

    In recent work, various design techniques were applied to investigate the feasibility of controlling the bandwidth and bandshape profiles of tungsten/boron-carbon (W/B 4 C) and tungsten/silicon (W/Si) multilayers for optimizing their performance in synchrotron radiation based angiographical imaging systems at 33 keV. Varied parameters included alternative spacing geometries, material thickness ratios, and numbers of layer pairs. Planar optics with nominal design reflectivities of 30%--94% and bandwidths ranging from 0.6%--10% were designed at the Stanford Radiation Laboratory, fabricated by the Ovonic Synthetic Materials Company, and characterized on Beam Line 4-3 at the Stanford Synchrotron Radiation Laboratory, in this paper we report selected results of these tests and review the possible use of the multilayers for determining optimal signal to noise vs. artifact signal ratios in practical Dual-Energy Digital Subtraction Angiography systems

  13. Design and prototyping of a wristband-type wireless photoplethysmographic device for heart rate variability signal analysis.

    Science.gov (United States)

    Ghamari, M; Soltanpur, C; Cabrera, S; Romero, R; Martinek, R; Nazeran, H

    2016-08-01

    Heart Rate Variability (HRV) signal analysis provides a quantitative marker of the Autonomic Nervous System (ANS) function. A wristband-type wireless photoplethysmographic (PPG) device was custom-designed to collect and analyze the arterial pulse in the wrist. The proposed device is comprised of an optical sensor to monitor arterial pulse, a signal conditioning unit to filter and amplify the analog PPG signal, a microcontroller to digitize the analog PPG signal, and a Bluetooth module to transfer the data to a smart device. This paper proposes a novel model to represent the PPG signal as the summation of two Gaussian functions. The paper concludes with a verification procedure for HRV signal analysis during sedentary activities.

  14. An optimized cosine-modulated nonuniform filter bank design for subband coding of ECG signal

    Directory of Open Access Journals (Sweden)

    A. Kumar

    2015-07-01

    Full Text Available A simple iterative technique for the design of nonuniform cosine modulated filter banks (CMFBS is presented in this paper. The proposed technique employs a single parameter for optimization. The nonuniform cosine modulated filter banks are derived by merging the adjacent filters of uniform cosine modulated filter banks. The prototype filter is designed with the aid of different adjustable window functions such as Kaiser, Cosh and Exponential, and by using the constrained equiripple finite impulse response (FIR digital filter design technique. In this method, either cut off frequency or passband edge frequency is varied in order to adjust the filter coefficients so that reconstruction error could be optimized/minimized to zero. Performance and effectiveness of the proposed method in terms of peak reconstruction error (PRE, aliasing distortion (AD, computational (CPU time, and number of iteration (NOI have been shown through the numerical examples and comparative studies. Finally, the technique is exploited for the subband coding of electrocardiogram (ECG and speech signals.

  15. Design and evaluation of an architecture for a digital signal processor for instrumentation applications

    Science.gov (United States)

    Fellman, Ronald D.; Kaneshiro, Ronald T.; Konstantinides, Konstantinos

    1990-03-01

    The authors present the design and evaluation of an architecture for a monolithic, programmable, floating-point digital signal processor (DSP) for instrumentation applications. An investigation of the most commonly used algorithms in instrumentation led to a design that satisfies the requirements for high computational and I/O (input/output) throughput. In the arithmetic unit, a 16- x 16-bit multiplier and a 32-bit accumulator provide the capability for single-cycle multiply/accumulate operations, and three format adjusters automatically adjust the data format for increased accuracy and dynamic range. An on-chip I/O unit is capable of handling data block transfers through a direct memory access port and real-time data streams through a pair of parallel I/O ports. I/O operations and program execution are performed in parallel. In addition, the processor includes two data memories with independent addressing units, a microsequencer with instruction RAM, and multiplexers for internal data redirection. The authors also present the structure and implementation of a design environment suitable for the algorithmic, behavioral, and timing simulation of a complete DSP system. Various benchmarking results are reported.

  16. Human engineering design considerations for the use of signal color enhancement in ASW displays

    Energy Technology Data Exchange (ETDEWEB)

    Banks, W.W.

    1990-11-01

    The Lawrence Livermore National Laboratory (LLNL) was requested to examine and define man-machine limits as part of the Office of Naval Technology's High Gain Initiative program (HGI). As an initial investigative area, LLNL's Systems and Human Performance effort focused upon color display interfaces and the use of color enhancement techniques to define human and system interface limits in signal detection and discrimination tasks. The knowledgeable and prudent use of color in different types of display is believed to facilitate human visual detection, discrimination and recognition in complex visual tasks. The consideration and understanding of the complex set of interacting variables associated with the prudent use of color is essential to optimize human performance, especially in the ASW community. The designers of advanced display technology and signal processing algorithms may be eventually called upon to present pre-processed information to ASW operators and researchers using the latest color enhancement techniques. These techniques, however, may be limited if one does not understand the complexity and limits of human information processing which reflects the assessed state of knowledge relevant to the use of color in displays. The initial sections of this report discuss various aspects of color presentation and the problems typically encountered, while the last section deals with a specific research proposal required to further our understanding and proper use of color enhancement methods.

  17. Design of the incentive mechanism in electricity auction market based on the signaling game theory

    International Nuclear Information System (INIS)

    Liu, Zhen; Zhang, Xiliang; Lieu, Jenny

    2010-01-01

    At present, designing a proper bidding mechanism to decrease the generators' market power is considered to be one of the key approaches to deepen the reform of the electricity market. Based on the signaling game theory, the paper analyzes the main electricity bidding mechanisms in the electricity auction markets and considers the degree of information disturbance as an important factor for evaluating bidding mechanisms. Under the above studies, an incentive electricity bidding mechanism defined as the Generator Semi-randomized Matching (GSM) mechanism is proposed. In order to verify the new bidding mechanism, this paper uses the Swarm platform to develop a simulation model based on the multi-agents. In the simulation model, the generators and purchasers use the partly superior study strategy to adjust their price and their electricity quantity. Then, the paper examines a simulation experiment of the GSM bidding mechanism and compares it to a simulation of the High-Low Matching (HLM) bidding mechanism. According to the simulation results, several conclusions can be drawn when comparing the proposed GSM bidding mechanism to the equilibrium state of HLM: the clearing price decreases, the total transaction volume increases, the profits of electricity generators decreases, and the overall benefits of purchasers increases. Index Terms - signaling game; semi-randomized matching; high-low match. (author)

  18. Signal Words

    Science.gov (United States)

    SIGNAL WORDS TOPIC FACT SHEET NPIC fact sheets are designed to answer questions that are commonly asked by the ... making decisions about pesticide use. What are Signal Words? Signal words are found on pesticide product labels, ...

  19. Design of LQG Controller for Active Suspension without Considering Road Input Signals

    Directory of Open Access Journals (Sweden)

    Hui Pang

    2017-01-01

    Full Text Available As the road conditions are completely unknown in the design of a suspension controller, an improved linear quadratic and Gaussian distributed (LQG controller is proposed for active suspension system without considering road input signals. The main purpose is to optimize the vehicle body acceleration, pitching angular acceleration, displacement of suspension system, and tire dynamic deflection comprehensively. Meanwhile, it will extend the applicability of the LQG controller. Firstly, the half-vehicle and road input mathematical models of an active suspension system are established, with the weight coefficients of each evaluating indicator optimized by using genetic algorithm (GA. Then, a simulation model is built in Matlab/Simulink environment. Finally, a comparison of simulation is conducted to illustrate that the proposed LQG controller can obtain the better comprehensive performance of vehicle suspension system and improve riding comfort and handling safety compared to the conventional one.

  20. Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis.

    Science.gov (United States)

    Kim, Okseon; Jeong, Yujeong; Lee, Hyunseung; Hong, Sun-Sun; Hong, Sungwoo

    2011-04-14

    Phosphatidylinositol 3-kinase α (PI3Kα) is an important regulator of intracellular signaling pathways, controlling remarkably diverse arrays of physiological processes. Because the PI3K pathway is frequently up-regulated in human cancers, the inhibition of PI3Kα can be a promising approach to cancer therapy. In this study, we have designed and synthesized a new series of imidazo[1,2-a]pyridine derivatives as PI3Kα inhibitors through the fragment-growing strategy. By varying groups at the 3- and 6-positions of imidazo[1,2-a]pyridines, we studied the structure-activity relationships (SAR) profiles and identified a series of potent PI3Kα inhibitors. Representative derivatives showed good activity in cellular proliferation and apoptosis assays. Moreover, these inhibitors exhibited noteworthy antiangiogenic activity.

  1. Design, parametrization, and pole placement of stabilizing output feedback compensators via injective cogenerator quotient signal modules.

    Science.gov (United States)

    Blumthaler, Ingrid; Oberst, Ulrich

    2012-03-01

    Control design belongs to the most important and difficult tasks of control engineering and has therefore been treated by many prominent researchers and in many textbooks, the systems being generally described by their transfer matrices or by Rosenbrock equations and more recently also as behaviors. Our approach to controller design uses, in addition to the ideas of our predecessors on coprime factorizations of transfer matrices and on the parametrization of stabilizing compensators, a new mathematical technique which enables simpler design and also new theorems in spite of the many outstanding results of the literature: (1) We use an injective cogenerator signal module ℱ over the polynomial algebra [Formula: see text] (F an infinite field), a saturated multiplicatively closed set T of stable polynomials and its quotient ring [Formula: see text] of stable rational functions. This enables the simultaneous treatment of continuous and discrete systems and of all notions of stability, called T-stability. We investigate stabilizing control design by output feedback of input/output (IO) behaviors and study the full feedback IO behavior, especially its autonomous part and not only its transfer matrix. (2) The new technique is characterized by the permanent application of the injective cogenerator quotient signal module [Formula: see text] and of quotient behaviors [Formula: see text] of [Formula: see text]-behaviors B. (3) For the control tasks of tracking, disturbance rejection, model matching, and decoupling and not necessarily proper plants we derive necessary and sufficient conditions for the existence of proper stabilizing compensators with proper and stable closed loop behaviors, parametrize all such compensators as IO behaviors and not only their transfer matrices and give new algorithms for their construction. Moreover we solve the problem of pole placement or spectral assignability for the complete feedback behavior. The properness of the full feedback behavior

  2. Signal detection circuit design of HCN measurement system based on TDLAS

    Science.gov (United States)

    He, Chungui; Zhang, Yujun; Chen, Chen; Lu, Yibing; Liu, Guohua; Gao, Yanwei; You, Kun; He, Ying; Zhang, Kai; Liu, Wenqing

    2016-10-01

    Hydrogen cyanide gas leakage may exist in the petrochemical industry, smelting plant, and other industrial processes, causing serious harm to the environment, and even threatening the safety of personnel. So the continuous detection of HCN gas plays an important role in the prevention of risk in production process and storage environment that existing hydrogen cyanide gas. The Tunable Diode Laser Technology (TDLAS) has advantages of non-contact, high sensitivity, high selectivity, and fast response time, etc., which is one of the ideal method of gas detection technologies and can be used to measure the hydrogen cyanide concentration. This paper studies the HCN detection system based on TDLAS technology, selects the absorption lines of hydrogen cyanide in 6539.12cm-1, and utilizes the center wavelength of 1.529μm distributed feedback (DFB) laser as a light source. It is discussed in detail on technical requirements of a high frequency modulated laser signal detection circuit, including noise level, gain, and bandwidth. Based on the above theory, the high frequency modulation preamplifier circuit and main amplifier circuit are designed for InGaAs photoelectric detector. The designed circuits are calculation analyzed with corresponding formula and simulation analyzed based on the Multisim software.

  3. Design and implementation of a data acquisition system for the study of dynamics signals in the time Domain

    International Nuclear Information System (INIS)

    Daza, Arnoldo; Hinojosa, Ana; Diaz, Xavier; Neira, Oscar

    2011-01-01

    The purpose of this research was to design and implement a data acquisition system for the study of dynamic signals in the time in order of nanoseconds, through the use of electronic instrumentation to obtain the temporal profiles of light signals, such as pulses of light from a laser or fluorescent light signals. To carry out the design and implementation of the data acquisition system proposed, we used a rapid response transducer and a data acquisition card of high speed. As well, it was developed a graphical user interface for visualization, analysis and study of the data acquired. Thus, it was possible to perform the digitization of a pulse on the order of nanoseconds, as well as the acquisition of fluorescence signals of different wavelengths, from which to obtain theoretical and experimental valuable knowledge based on the physics of spectroscopy.

  4. The design and implementation of signal decomposition system of CL multi-wavelet transform based on DSP builder

    Science.gov (United States)

    Huang, Yan; Wang, Zhihui

    2015-12-01

    With the development of FPGA, DSP Builder is widely applied to design system-level algorithms. The algorithm of CL multi-wavelet is more advanced and effective than scalar wavelets in processing signal decomposition. Thus, a system of CL multi-wavelet based on DSP Builder is designed for the first time in this paper. The system mainly contains three parts: a pre-filtering subsystem, a one-level decomposition subsystem and a two-level decomposition subsystem. It can be converted into hardware language VHDL by the Signal Complier block that can be used in Quartus II. After analyzing the energy indicator, it shows that this system outperforms Daubenchies wavelet in signal decomposition. Furthermore, it has proved to be suitable for the implementation of signal fusion based on SoPC hardware, and it will become a solid foundation in this new field.

  5. Accelerating SystemVerilog UVM Based VIP to Improve Methodology for Verification of Image Signal Processing Designs Using HW Emulator

    OpenAIRE

    Jain, Abhishek; Gupta, Piyush Kumar; Gupta, Dr. Hima; Dhar, Sachish

    2014-01-01

    In this paper we present the development of Acceleratable UVCs from standard UVCs in SystemVerilog and their usage in UVM based Verification Environment of Image Signal Processing designs to increase run time performance. This paper covers development of Acceleratable UVCs from standard UVCs for internal control and data buses of ST imaging group by partitioning of transaction-level components and cycle-accurate signal-level components between the software simulator and hardware accelerator r...

  6. Designing driver assistance systems with crossmodal signals: multisensory integration rules for saccadic reaction times apply.

    Directory of Open Access Journals (Sweden)

    Rike Steenken

    Full Text Available Modern driver assistance systems make increasing use of auditory and tactile signals in order to reduce the driver's visual information load. This entails potential crossmodal interaction effects that need to be taken into account in designing an optimal system. Here we show that saccadic reaction times to visual targets (cockpit or outside mirror, presented in a driving simulator environment and accompanied by auditory or tactile accessories, follow some well-known spatiotemporal rules of multisensory integration, usually found under confined laboratory conditions. Auditory nontargets speed up reaction time by about 80 ms. The effect tends to be maximal when the nontarget is presented 50 ms before the target and when target and nontarget are spatially coincident. The effect of a tactile nontarget (vibrating steering wheel was less pronounced and not spatially specific. It is shown that the average reaction times are well-described by the stochastic "time window of integration" model for multisensory integration developed by the authors. This two-stage model postulates that crossmodal interaction occurs only if the peripheral processes from the different sensory modalities terminate within a fixed temporal interval, and that the amount of crossmodal interaction manifests itself in an increase or decrease of second stage processing time. A qualitative test is consistent with the model prediction that the probability of interaction, but not the amount of crossmodal interaction, depends on target-nontarget onset asynchrony. A quantitative model fit yields estimates of individual participants' parameters, including the size of the time window. Some consequences for the design of driver assistance systems are discussed.

  7. Design of eddy current probes and signal inversion for non-destructive testing

    International Nuclear Information System (INIS)

    Ravat, C.

    2008-01-01

    Non destructive testing is widely used in aerospace industry and nuclear industry. The growing complexity of industrial processes and manufactured parts, the increasing need of safety in service and the will of life span optimization, require more and more complex quality evaluations to be set up. Among the different anomalies to consider, sub-millimetric breaking surface notches have to be subject to special care. Indeed, it often constitutes a start to larger notches, which can cause the destruction of parts. Penetrant testing is nowadays widely used for that kind of defect, owing to its good performances. Nevertheless, it should be eventually dropped because of environmental norms. Among the possible substitution solutions, the use of eddy currents (EC) for conductive parts is a reliable, fast and inexpensive alternative. The study is about the conception and the use of multi-elements EC probe structures featuring microsensors for non destructive testing of surface breaking defects. A methodology has been established in order to develop such structures and to compare their performances within the framework of sub-millimetric surface breaking notch research. These structures has been employed for calibrated notches evaluation with a specific acquisition bench. Original detection and defect characterization algorithms have been designed and implemented on acquired signals. The most efficient structure has been determined, the notch detection quality has been quantified, and the geometric characteristics of notches has been estimated. (author)

  8. An intelligent vehicular traffic signal control system with state flow chart design and fpga prototyping

    International Nuclear Information System (INIS)

    Solangi, U.S.; Memon, T.D.; Noonari, A.S.; Ansari, O.A.

    2017-01-01

    The problem of vehicular traffic congestion is a persistent constraint in the socio-economic development of Pakistan. This paper presents design and implementation of an intelligent traffic controller based on FPGA (Field Programmable Gate Array) to provide an efficient traffic management by optimizing functioning of traffic lights which will result in minimizing traffic congestion at intersections. The existent Traffic Signal system in Pakistan is fixed-time based and offers only Open Loop method for Traffic Control. The Intelligent Traffic Controller presented here uses feedback sensors to read the Traffic density present at a four way intersection to provide an efficient alternative for better supervisory Control of Traffic flow. The traffic density based control logic has been developed in a State Flow Chart for improved visualization of State Machine based operation, and implemented as a Subsystem in Simulink and transferred into VHDL (Hardware Description Language) code using HDL Coder for reducing development time and time to market, which are essential to capitalize Embedded Systems Market. The VHDL code is synthesized with Altera QUARTUS, simulated timing waveform is obtained to verify correctness of the algorithm for different Traffic Scenarios. For implementation purpose estimations were obtained for Cyclone-III and Stratix-III. (author)

  9. An Intelligent Vehicular Traffic Signal Control System with State Flow Chart Design and FPGA Prototyping

    Directory of Open Access Journals (Sweden)

    UMAIR SAEEDSOLANGI

    2017-04-01

    Full Text Available The problem of vehicular traffic congestion is a persistent constraint in the socio-economic development of Pakistan. This paper presents design and implementation of an intelligent traffic controller based on FPGA (Field Programmable Gate Array to provide an efficient traffic management by optimizing functioning of traffic lights which will result in minimizing traffic congestion at intersections. The existent Traffic Signal system in Pakistan is fixed-time based and offers only Open Loop method for Traffic Control. The Intelligent Traffic Controller presented here uses feedback sensors to read the Traffic density present at a four way intersection to provide an efficient alternative for better supervisory Control of Traffic flow. The traffic density based control logic has been developed in a State Flow Chart for improved visualization of State Machine based operation, and implemented as a Subsystem in Simulink and transferred into VHDL (Hardware Description Language code using HDL Coder for reducing development time and time to market, which are essential to capitalize Embedded Systems Market. The VHDL code is synthesized with Altera QUARTUS, simulated timing waveform is obtained to verify correctness of the algorithm for different Traffic Scenarios. For implementation purpose estimations were obtained for Cyclone-III and Stratix-III.

  10. Extreme temperature robust optical sensor designs and fault-tolerant signal processing

    Science.gov (United States)

    Riza, Nabeel Agha [Oviedo, FL; Perez, Frank [Tujunga, CA

    2012-01-17

    Silicon Carbide (SiC) probe designs for extreme temperature and pressure sensing uses a single crystal SiC optical chip encased in a sintered SiC material probe. The SiC chip may be protected for high temperature only use or exposed for both temperature and pressure sensing. Hybrid signal processing techniques allow fault-tolerant extreme temperature sensing. Wavelength peak-to-peak (or null-to-null) collective spectrum spread measurement to detect wavelength peak/null shift measurement forms a coarse-fine temperature measurement using broadband spectrum monitoring. The SiC probe frontend acts as a stable emissivity Black-body radiator and monitoring the shift in radiation spectrum enables a pyrometer. This application combines all-SiC pyrometry with thick SiC etalon laser interferometry within a free-spectral range to form a coarse-fine temperature measurement sensor. RF notch filtering techniques improve the sensitivity of the temperature measurement where fine spectral shift or spectrum measurements are needed to deduce temperature.

  11. Design of excitation signals for active system monitoring in a performance assessment setup

    DEFF Research Database (Denmark)

    Green, Torben; Izadi-Zamanabadi, Roozbeh; Niemann, Hans Henrik

    2011-01-01

    This paper investigates how the excitation signal should be chosen for a active performance setup. The signal is used in a setup where the main purpose is to detect whether a parameter change of the controller has changed the global performance significantly. The signal has to be able to excite...... the dynamics of the subsystem under investigation both before and after the parameter change. The controller is well know, but there exists no detailed knowledge about the dynamics of the subsystem....

  12. Evolution and Design Governing Signal Precision and Amplification in a Bacterial Chemosensory Pathway.

    Directory of Open Access Journals (Sweden)

    Mathilde Guzzo

    2015-08-01

    Full Text Available Understanding the principles underlying the plasticity of signal transduction networks is fundamental to decipher the functioning of living cells. In Myxococcus xanthus, a particular chemosensory system (Frz coordinates the activity of two separate motility systems (the A- and S-motility systems, promoting multicellular development. This unusual structure asks how signal is transduced in a branched signal transduction pathway. Using combined evolution-guided and single cell approaches, we successfully uncoupled the regulations and showed that the A-motility regulation system branched-off an existing signaling system that initially only controlled S-motility. Pathway branching emerged in part following a gene duplication event and changes in the circuit structure increasing the signaling efficiency. In the evolved pathway, the Frz histidine kinase generates a steep biphasic response to increasing external stimulations, which is essential for signal partitioning to the motility systems. We further show that this behavior results from the action of two accessory response regulator proteins that act independently to filter and amplify signals from the upstream kinase. Thus, signal amplification loops may underlie the emergence of new connectivity in signal transduction pathways.

  13. Optimal signal constellation design for ultra-high-speed optical transport in the presence of nonlinear phase noise.

    Science.gov (United States)

    Liu, Tao; Djordjevic, Ivan B

    2014-12-29

    In this paper, we first describe an optimal signal constellation design algorithm suitable for the coherent optical channels dominated by the linear phase noise. Then, we modify this algorithm to be suitable for the nonlinear phase noise dominated channels. In optimization procedure, the proposed algorithm uses the cumulative log-likelihood function instead of the Euclidian distance. Further, an LDPC coded modulation scheme is proposed to be used in combination with signal constellations obtained by proposed algorithm. Monte Carlo simulations indicate that the LDPC-coded modulation schemes employing the new constellation sets, obtained by our new signal constellation design algorithm, outperform corresponding QAM constellations significantly in terms of transmission distance and have better nonlinearity tolerance.

  14. Input/output Buffer based Vedic Multiplier Design for Thermal Aware Energy Efficient Digital Signal Processing on 28nm FPGA

    DEFF Research Database (Denmark)

    Goswami, Kavita; Pandey, Bishwajeet; Hussain, Dil muhammed Akbar

    2016-01-01

    Multiplier is used for multiplication of a signal and a constant in digital signal processing (DSP). 28nm technology based Vedic multiplier is implemented with use of VHDL HDL, Xilinx ISE, Kintex-7 FPGA and XPower Analyzer. Vedic multiplier gain speed improvements by parallelizing the generation...... Programmable Gate Array (FPGA) in order to reduce the development cost. The development cost for Application Specific Integrated Circuits (ASICs) are high in compare to FPGA. Selection of the most energy efficient IO standards in place of signal gating is the main design methodology for design of energy...... efficient Vedic multiplier.There is 68.51%, 69.86%, 74.65%, and 78.39% contraction in total power of Vedic multiplier on 28nm Kintex-7 FPGA, when we use HSTL_II in place of HSTL_II_DCI_18 at 56.7oC, 53.5oC, 40oC and 21oC respectively....

  15. Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction

    Science.gov (United States)

    Hu, Jianfei; Neiswinger, Johnathan; Zhang, Jin; Zhu, Heng; Qian, Jiang

    2015-01-01

    Scaffold proteins play a crucial role in facilitating signal transduction in eukaryotes by bringing together multiple signaling components. In this study, we performed a systematic analysis of scaffold proteins in signal transduction by integrating protein-protein interaction and kinase-substrate relationship networks. We predicted 212 scaffold proteins that are involved in 605 distinct signaling pathways. The computational prediction was validated using a protein microarray-based approach. The predicted scaffold proteins showed several interesting characteristics, as we expected from the functionality of scaffold proteins. We found that the scaffold proteins are likely to interact with each other, which is consistent with previous finding that scaffold proteins tend to form homodimers and heterodimers. Interestingly, a single scaffold protein can be involved in multiple signaling pathways by interacting with other scaffold protein partners. Furthermore, we propose two possible regulatory mechanisms by which the activity of scaffold proteins is coordinated with their associated pathways through phosphorylation process. PMID:26393507

  16. Direction of Radio Finding via MUSIC (Multiple Signal Classification) Algorithm for Hardware Design System

    Science.gov (United States)

    Zhang, Zheng

    2017-10-01

    Concept of radio direction finding systems, which use radio direction finding is based on digital signal processing algorithms. Thus, the radio direction finding system becomes capable to locate and track signals by the both. Performance of radio direction finding significantly depends on effectiveness of digital signal processing algorithms. The algorithm uses the Direction of Arrival (DOA) algorithms to estimate the number of incidents plane waves on the antenna array and their angle of incidence. This manuscript investigates implementation of the DOA algorithms (MUSIC) on the uniform linear array in the presence of white noise. The experiment results exhibit that MUSIC algorithm changed well with the radio direction.

  17. On the Design of an Efficient Cardiac Health Monitoring System Through Combined Analysis of ECG and SCG Signals.

    Science.gov (United States)

    Sahoo, Prasan Kumar; Thakkar, Hiren Kumar; Lin, Wen-Yen; Chang, Po-Cheng; Lee, Ming-Yih

    2018-01-28

    Cardiovascular disease (CVD) is a major public concern and socioeconomic problem across the globe. The popular high-end cardiac health monitoring systems such as magnetic resonance imaging (MRI), computerized tomography scan (CT scan), and echocardiography (Echo) are highly expensive and do not support long-term continuous monitoring of patients without disrupting their activities of daily living (ADL). In this paper, the continuous and non-invasive cardiac health monitoring using unobtrusive sensors is explored aiming to provide a feasible and low-cost alternative to foresee possible cardiac anomalies in an early stage. It is learned that cardiac health monitoring based on sole usage of electrocardiogram (ECG) signals may not provide powerful insights as ECG provides shallow information on various cardiac activities in the form of electrical impulses only. Hence, a novel low-cost, non-invasive seismocardiogram (SCG) signal along with ECG signals are jointly investigated for the robust cardiac health monitoring. For this purpose, the in-laboratory data collection model is designed for simultaneous acquisition of ECG and SCG signals followed by mechanisms for the automatic delineation of relevant feature points in acquired ECG and SCG signals. In addition, separate feature points based novel approach is adopted to distinguish between normal and abnormal morphology in each ECG and SCG cardiac cycle. Finally, a combined analysis of ECG and SCG is carried out by designing a Naïve Bayes conditional probability model. Experiments on Institutional Review Board (IRB) approved licensed ECG/SCG signals acquired from real subjects containing 12,000 cardiac cycles show that the proposed feature point delineation mechanisms and abnormal morphology detection methods consistently perform well and give promising results. In addition, experimental results show that the combined analysis of ECG and SCG signals provide more reliable cardiac health monitoring compared to the

  18. On the Design of an Efficient Cardiac Health Monitoring System Through Combined Analysis of ECG and SCG Signals

    Directory of Open Access Journals (Sweden)

    Prasan Kumar Sahoo

    2018-01-01

    Full Text Available Cardiovascular disease (CVD is a major public concern and socioeconomic problem across the globe. The popular high-end cardiac health monitoring systems such as magnetic resonance imaging (MRI, computerized tomography scan (CT scan, and echocardiography (Echo are highly expensive and do not support long-term continuous monitoring of patients without disrupting their activities of daily living (ADL. In this paper, the continuous and non-invasive cardiac health monitoring using unobtrusive sensors is explored aiming to provide a feasible and low-cost alternative to foresee possible cardiac anomalies in an early stage. It is learned that cardiac health monitoring based on sole usage of electrocardiogram (ECG signals may not provide powerful insights as ECG provides shallow information on various cardiac activities in the form of electrical impulses only. Hence, a novel low-cost, non-invasive seismocardiogram (SCG signal along with ECG signals are jointly investigated for the robust cardiac health monitoring. For this purpose, the in-laboratory data collection model is designed for simultaneous acquisition of ECG and SCG signals followed by mechanisms for the automatic delineation of relevant feature points in acquired ECG and SCG signals. In addition, separate feature points based novel approach is adopted to distinguish between normal and abnormal morphology in each ECG and SCG cardiac cycle. Finally, a combined analysis of ECG and SCG is carried out by designing a Naïve Bayes conditional probability model. Experiments on Institutional Review Board (IRB approved licensed ECG/SCG signals acquired from real subjects containing 12,000 cardiac cycles show that the proposed feature point delineation mechanisms and abnormal morphology detection methods consistently perform well and give promising results. In addition, experimental results show that the combined analysis of ECG and SCG signals provide more reliable cardiac health monitoring compared to

  19. Design, Fabrication and Experimental Validation of a Novel Dry-Contact Sensor for Measuring Electroencephalography Signals without Skin Preparation

    Directory of Open Access Journals (Sweden)

    Chin-Teng Lin

    2011-05-01

    Full Text Available In the present study, novel dry-contact sensors for measuring electro-encephalography (EEG signals without any skin preparation are designed, fabricated by an injection molding manufacturing process and experimentally validated. Conventional wet electrodes are commonly used to measure EEG signals; they provide excellent EEG signals subject to proper skin preparation and conductive gel application. However, a series of skin preparation procedures for applying the wet electrodes is always required and usually creates trouble for users. To overcome these drawbacks, novel dry-contact EEG sensors were proposed for potential operation in the presence or absence of hair and without any skin preparation or conductive gel usage. The dry EEG sensors were designed to contact the scalp surface with 17 spring contact probes. Each probe was designed to include a probe head, plunger, spring, and barrel. The 17 probes were inserted into a flexible substrate using a one-time forming process via an established injection molding procedure. With these 17 spring contact probes, the flexible substrate allows for high geometric conformity between the sensor and the irregular scalp surface to maintain low skin-sensor interface impedance. Additionally, the flexible substrate also initiates a sensor buffer effect, eliminating pain when force is applied. The proposed dry EEG sensor was reliable in measuring EEG signals without any skin preparation or conductive gel usage, as compared with the conventional wet electrodes.

  20. Operation, analysis, and design of signalized intersections : a module for the introductory course in transportation engineering.

    Science.gov (United States)

    2014-02-01

    This report presents materials that can be used as the basis for a module on signalized intersections in the introductory : course in transportation engineering. The materials were developed based on studies of the work of students who took : this in...

  1. Fatigue Resistant Design Criteria for MD SHA Cantilevered Mast Arm Signal Structure : Research Summary

    Science.gov (United States)

    2017-12-01

    Over the past two decades, wind induced fatigue cracking of highway signs, luminaires, and traffic signal support structures have been increasingly reported all over the United States. While fatalities associated with these failures have been limited...

  2. Traffic design and signal timing of staggered intersections based on a sorting strategy

    Directory of Open Access Journals (Sweden)

    Zhengyi Cai

    2016-04-01

    Full Text Available A staggered intersection is a special type of intersection in a road network. Its geographical characteristics consist of two T-legged intersections that cause the lost time per cycle to become longer than at cross intersections under conventional signal control, thus leading to low intersection efficiency. This article shows that the problem can be eliminated at the left–right type of staggered intersection by channelization and signal phasing, based on a sorting strategy and pre-signal, which reduce the amount of lost time during the signal cycle using the split distance as the sorting area. VISSIM was used to model and analyze the proposed method as well as the conventional method for comparison purposes. The simulation revealed that the proposed method reduced the average delays and maximum queue lengths in each movement and for the entire intersection, both in the peak hours and in the off-peak hour.

  3. Design and implementation of an electrocardiographical signal acquisition and digital processing system orientated to the detection of paroxysmal arrhythmias

    International Nuclear Information System (INIS)

    Braceli, Agustín Iriart; Morani, Jorge Exequiel

    2011-01-01

    This article describes the design, technical aspects and implementation of a device capable of acquiring electrocardiograph signals; visualize them in real time over a graphic liquid crystal display (GLCD), and the storage of these ECG registers on a SD memory card. It also details a noise suppression algorithm using the Wavelet Transform. This system was specially developed to cover some bankruptcy that presents actual Holters or ECG regarding the detection of paroxysmal arrhythmias. The contribution of this work is settled on its portability and low production cost. The filtering method used provides an ECG signal without any significant noise and appropriate to the diagnosis of cardiac pathologies.

  4. Design and implementation of an electrocardiographical signal acquisition and digital processing system orientated to the detection of paroxysmal arrhythmias

    Science.gov (United States)

    Iriart Braceli, Agustín; Exequiel Morani, Jorge

    2011-12-01

    This article describes the design, technical aspects and implementation of a device capable of acquiring electrocardiograph signals; visualize them in real time over a graphic liquid crystal display (GLCD), and the storage of these ECG registers on a SD memory card. It also details a noise suppression algorithm using the Wavelet Transform. This system was specially developed to cover some bankruptcy that presents actual Holters or ECG regarding the detection of paroxysmal arrhythmias. The contribution of this work is settled on its portability and low production cost. The filtering method used provides an ECG signal without any significant noise and appropriate to the diagnosis of cardiac pathologies.

  5. Transmission and signal loss in mask designs for a dual neutron and gamma imager applied to mobile standoff detection

    International Nuclear Information System (INIS)

    Ayaz-Maierhafer, Birsen; Hayward, Jason P.; Ziock, Klaus P.; Blackston, Matthew A.; Fabris, Lorenzo

    2013-01-01

    In order to design a next-generation, dual neutron and gamma imager for mobile standoff detection which uses coded aperture imaging as its primary detection modality, the following design parameters have been investigated for gamma and neutron radiation incident upon a hybrid, coded mask: (1) transmission through mask elements for various mask materials and thicknesses; and (2) signal attenuation in the mask versus angle of incidence. Each of these parameters directly affects detection significance, as quantified by the signal-to-noise ratio. The hybrid mask consists of two or three layers: organic material for fast neutron attenuation and scattering, Cd for slow neutron absorption (if applied), and one of three of the following photon or photon and slow neutron attenuating materials—Linotype alloy, CLYC, or CZT. In the MCNP model, a line source of gamma rays (100–2500 keV), fast neutrons (1000–10,000 keV) or thermal neutrons was positioned above the hybrid mask. The radiation penetrating the mask was simply tallied at the surface of an ideal detector, which was located below the surface of the last mask layer. The transmission was calculated as the ratio of the particles transmitted through the fixed aperture to the particles passing through the closed mask. In order to determine the performance of the mask considering relative motion between the source and detector, simulations were used to calculate the signal attenuation for incident radiation angles of 0–50°. The results showed that a hybrid mask can be designed to sufficiently reduce both transmission through the mask and signal loss at large angles of incidence, considering both gamma ray and fast neutron radiations. With properly selected material thicknesses, the signal loss of a hybrid mask, which is necessarily thicker than the mask required for either single mode imaging, is not a setback to the system's detection significance

  6. [Design of High Frequency Signal Detecting Circuit of Human Body Impedance Used for Ultrashort Wave Diathermy Apparatus].

    Science.gov (United States)

    Fan, Xu; Wang, Yunguang; Cheng, Haiping; Chong, Xiaochen

    2016-02-01

    The present circuit was designed to apply to human tissue impedance tuning and matching device in ultra-short wave treatment equipment. In order to judge if the optimum status of circuit parameter between energy emitter circuit and accepter circuit is in well syntony, we designed a high frequency envelope detect circuit to coordinate with automatic adjust device of accepter circuit, which would achieve the function of human tissue impedance matching and tuning. Using the sampling coil to receive the signal of amplitude-modulated wave, we compared the voltage signal of envelope detect circuit with electric current of energy emitter circuit. The result of experimental study was that the signal, which was transformed by the envelope detect circuit, was stable and could be recognized by low speed Analog to Digital Converter (ADC) and was proportional to the electric current signal of energy emitter circuit. It could be concluded that the voltage, transformed by envelope detect circuit can mirror the real circuit state of syntony and realize the function of human tissue impedance collecting.

  7. Design and Test of a Signal Packet Router Prototype for the ATLAS NSW sTGC Detector

    CERN Document Server

    Hu, Xueye; The ATLAS collaboration

    2016-01-01

    Abstract– The New Small Wheel (NSW) small-strip thin-gap chambers (sTGC) detector will be installed in Large Hadron Collider (LHC) during ATLAS Phase-I upgrade. For sTGC detector, it requires very high-speed electronic triggering of signal events. On detecting a signal peak, sTGC front-end trigger logic will send out serialized track information on twinax fast serial copper wires to the signal packet Router on the periphery of the new small wheel. The signal packet Router boards handle all incoming traffic from the TDS chips (4.8 Gbps), serving as a very fast switching-yard between incoming active TDS signals and a limited number of optoelectronic outputs. There are several design requirements on router: radiation-hard (9kRad), high-speed serial link and low fixed latency in FPGA (field-programmable gate array) data processing. To meet those requirements, a router prototype has been developed for demonstration purpose. The components used in router prototype have been tested in radiation environment to m...

  8. Fatigue Resistant Design Criteria for MD SHA Cantilevered Mast Arm Signal Structure

    Science.gov (United States)

    2017-12-01

    The fatigue design of the mast arm structures and connections vary significantly based on the Category of Importance factor adopted and the load cases for fatigue design loads. Consideration should include the cost and size of the structures for both...

  9. Design reuse in product shape modeling : A study of freeform feature reuse by signal processing techniques

    NARCIS (Netherlands)

    Wang, C.

    2005-01-01

    Lack of facilities in supporting design reuse is a serious problem in product shape modeling, especially in computer-aided design systems. This becomes a bottleneck of fast shape conceptualization and creation in consumer product design, which consequently prohibits creativity and innovation. In the

  10. The Analysis of Design of Robust Nonlinear Estimators and Robust Signal Coding Schemes.

    Science.gov (United States)

    1982-09-16

    b - )’/ 12. between uniform and nonuniform quantizers. For the nonuni- Proof: If b - acca then form quantizer we can expect the mean-square error to...in the window greater than or equal to the value at We define f7 ’(s) as the n-times filtered signal p + 1; consequently, point p + 1 is the median and

  11. Signal-to-Noise ratio and design complexity based on Unified Loss ...

    African Journals Online (AJOL)

    Taguchi's quality loss function for larger-the-better performance characteristics uses a reciprocal transformation to compute quality loss. This paper suggests that reciprocal transformation unnecessarily complicates and may distort results. Examples of this distortion include the signal-to-noise ratio based on mean squared ...

  12. Mechanical design parameters for detection of nuclear signals by magnetic resonance force microscopy

    International Nuclear Information System (INIS)

    Moore, G.J.; Hanlon, J.A.; Lamartine, B.; Hawley, M.; Solem, J.C.; Signer, S.; Jarmer, J.J.; Penttila, S.; Sillerud, L.O.; Pryputniewicz, R.J.

    1993-01-01

    Recent theoretical work has shown that mechanical detection of magnetic resonance from a single nuclear spin is in principle possible. This theory has recently been experimentally validated by the mechanical detection of electron spin resonance signals using microscale cantilevers. Currently we are extending this technology in an attempt to detect nuclear signals which are extending this technology in an attempt to detect nuclear signals which are three orders of magnitude lower in intensity than electron signals. In order to achieve the needed thousand-fold improvement in sensitivity we have undertaken the development of optimized mechanical cantilevers and highly polarized samples. Finite element modeling is used as a tool to simulate cantilever beam dynamics and to optimize the mechanical properties including Q, resonant frequency, amplitude of vibration and spring constant. Simulations are compared to experiments using heterodyne hologram interferometry. Nanofabrication of optimized cantilevers via ion milling will be directed by the outcome of these simulations and experiments. Highly polarized samples are developed using a three-fold approach: (1) high magnetic field strength (2.5T), (2) low temperature (1K), and (3) use of samples polarized by dynamic nuclear polarization. Our recent experiments have demonstrated nuclear polarizations in excess of 50% in molecules of toulene

  13. A Platform-Based Methodology for System-Level Mixed-Signal Design

    Directory of Open Access Journals (Sweden)

    Alberto Sangiovanni-Vincentelli

    2010-01-01

    Full Text Available The complexity of today's embedded electronic systems as well as their demanding performance and reliability requirements are such that their design can no longer be tackled with ad hoc techniques while still meeting tight time to-market constraints. In this paper, we present a system level design approach for electronic circuits, utilizing the platform-based design (PBD paradigm as the natural framework for mixed-domain design formalization. In PBD, a meet-in-the-middle approach allows systematic exploration of the design space through a series of top-down mapping of system constraints onto component feasibility models in a platform library, which is based on bottom-up characterizations. In this framework, new designs can be assembled from the precharacterized library components, giving the highest priority to design reuse, correct assembly, and efficient design flow from specifications to implementation. We apply concepts from design centering to enforce robustness to modeling errors as well as process, voltage, and temperature variations, which are currently plaguing embedded system design in deep-submicron technologies. The effectiveness of our methodology is finally shown on the design of a pipeline A/D converter and two receiver front-ends for UMTS and UWB communications.

  14. Design and Analysis of a New Hair Sensor for Multi-Physical Signal Measurement

    Directory of Open Access Journals (Sweden)

    Bo Yang

    2016-07-01

    Full Text Available A new hair sensor for multi-physical signal measurements, including acceleration, angular velocity and air flow, is presented in this paper. The entire structure consists of a hair post, a torsional frame and a resonant signal transducer. The hair post is utilized to sense and deliver the physical signals of the acceleration and the air flow rate. The physical signals are converted into frequency signals by the resonant transducer. The structure is optimized through finite element analysis. The simulation results demonstrate that the hair sensor has a frequency of 240 Hz in the first mode for the acceleration or the air flow sense, 3115 Hz in the third and fourth modes for the resonant conversion, and 3467 Hz in the fifth and sixth modes for the angular velocity transformation, respectively. All the above frequencies present in a reasonable modal distribution and are separated from interference modes. The input-output analysis of the new hair sensor demonstrates that the scale factor of the acceleration is 12.35 Hz/g, the scale factor of the angular velocity is 0.404 nm/deg/s and the sensitivity of the air flow is 1.075 Hz/(m/s2, which verifies the multifunction sensitive characteristics of the hair sensor. Besides, the structural optimization of the hair post is used to improve the sensitivity of the air flow rate and the acceleration. The analysis results illustrate that the hollow circular hair post can increase the sensitivity of the air flow and the II-shape hair post can increase the sensitivity of the acceleration. Moreover, the thermal analysis confirms the scheme of the frequency difference for the resonant transducer can prominently eliminate the temperature influences on the measurement accuracy. The air flow analysis indicates that the surface area increase of hair post is significantly beneficial for the efficiency improvement of the signal transmission. In summary, the structure of the new hair sensor is proved to be feasible by

  15. The Role of Diet in Shaping the Chemical Signal Design of Lacertid Lizards.

    Science.gov (United States)

    Baeckens, Simon; García-Roa, Roberto; Martín, José; Van Damme, Raoul

    2017-09-01

    Lizards communicate with others via chemical signals, the composition of which may vary among species. Although the selective pressures and constraints affecting chemical signal diversity at the species level remain poorly understood, the possible role of diet has been largely neglected. The chemical signals of many lizards originate from the femoral glands that exude a mixture of semiochemicals, and may be used in a variety of contexts. We analyzed the lipophilic fraction of the glandular secretions of 45 species of lacertid lizard species by gas chromatography/mass spectrometry. The proportions of nine major chemical classes (alcohols, aldehydes, fatty acids, furanones, ketones, steroids, terpenoids, tocopherols and waxy esters), the relative contributions of these different classes ('chemical diversity'), and the total number of different lipophilic compounds ('chemical richness') varied greatly among species. We examined whether interspecific differences in these chemical variables could be coupled to interspecific variation in diet using data from the literature. In addition, we compared chemical signal composition among species that almost never, occasionally, or often eat plant material. We found little support for the hypothesis that the chemical profile of a given species' secretion depends on the type of food consumed. Diet breadth did not correlate with chemical diversity or richness. The amount of plants or ants consumed did not affect the relative contribution of any of the nine major chemical classes to the secretion. Chemical diversity did not differ among lizards with different levels of plant consumption; however, chemical richness was low in species with an exclusive arthropod diet, suggesting that incorporating plants in the diet enables lizards to increase the number of compounds allocated to secretions, likely because a (partly) herbivorous diet allows them to include compounds of plant origin that are unavailable in animal prey. Still, overall

  16. Quantification, modelling and design for signal history dependent effects in mixed-signal SOI/SOS circuits; Quantification, modelisation et conception prenant en compte les etats anterieurs des signaux dans les circuits mixtes SOI/SOS

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, C.F.; Redman-White, W.; Bracey, M.; Tenbroek, B.M.; Lee, M.S. [Southampton Univ., Dept. of Electronics and Computer Sciences (United Kingdom); Uren, M.J.; Brunson, K.M. [DERA Farnborough, GU, Hants (United Kingdom)

    1999-07-01

    This paper deals with how the radiation hardness of mixed signal SOI/SOS CMOS circuits is taken into account at both architectural terms as well as the the transistor level cell designs. The primary issue is to deal with divergent transistor threshold shifts, and to understand the effects of large amplitude non stationary signals on analogue cell behaviour. (authors)

  17. Top-down design and verification methodology for analog mixed-signal integrated circuits

    NARCIS (Netherlands)

    Beviz, P.

    2016-01-01

    The current report contains the introduction of a novel Top-Down Design and Verification methodology for AMS integrated circuits. With the introduction of new design and verification flow, more reliable and efficient development of AMS ICs is possible. The assignment incorporated the research on the

  18. Synthesis of Intrinsically Disordered Fluorinated Peptides for Modular Design of High-Signal 19 F MRI Agents.

    Science.gov (United States)

    Kirberger, Steven E; Maltseva, Sofia D; Manulik, Joseph C; Einstein, Samuel A; Weegman, Bradley P; Garwood, Michael; Pomerantz, William C K

    2017-06-01

    19 F MRI is valuable for in vivo imaging due to the only trace amounts of fluorine in biological systems. Because of the low sensitivity of MRI however, designing new fluorochemicals remains a significant challenge for achieving sufficient 19 F signal. Here, we describe a new class of high-signal, water-soluble fluorochemicals as 19 F MRI imaging agents. A polyamide backbone is used for tuning the proteolytic stability to avoid retention within the body, which is a limitation of current state-of-the-art perfluorochemicals. We show that unstructured peptides containing alternating N-ϵ-trifluoroacetyllysine and lysine provide a degenerate 19 F NMR signal. 19 F MRI phantom images provide sufficient contrast at micromolar concentrations, showing promise for eventual clinical applications. Finally, the degenerate high signal characteristics were retained when conjugated to a large protein, indicating potential for in vivo targeting applications, including molecular imaging and cell tracking. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Efficient design of FIR filter based low-pass differentiators for biomedical signal processing

    Directory of Open Access Journals (Sweden)

    Wulf Michael

    2016-09-01

    Full Text Available This paper describes an alternative design of linear phase low-pass differentiators with a finite impulse response (type III FIR filter. To reduce the number of necessary filter coefficients, the differentiator’s transfer function is approximated by a Fourier series of a triangle function. Thereby the filter’s transition steepness towards the stopband is intentionally reduced. It can be shown that the proposed design of low-pass differentiators yields to similar results as other published design recommendations, while the filter order can be significantly reduced.

  20. A DESIGN FRAMEWORK FOR HUMAN EMOTION RECOGNITION USING ELECTROCARDIOGRAM AND SKIN CONDUCTANCE RESPONSE SIGNALS

    Directory of Open Access Journals (Sweden)

    KHAIRUN NISA’ MINHAD

    2017-11-01

    Full Text Available Identification of human emotional state while driving a vehicle can help in understanding the human behaviour. Based on this identification, a response system can be developed in order to mitigate the impact that may be resulted from the behavioural changes. However, the adaptation of emotions to the environment at most scenarios is subjective to an individual’s perspective. Many factors, mainly cultural and geography, gender, age, life style and history, level of education and professional status, can affect the detection of human emotional affective states. This work investigated sympathetic responses toward human emotions defined by using electrocardiography (ECG and skin conductance response (SCR signals recorded simultaneously. This work aimed to recognize ECG and SCR patterns of the investigated emotions measured using selected sensor. A pilot study was conducted to evaluate the proposed framework. Initial results demonstrated the importance of suitability of the stimuli used to evoke the emotions and high opportunity for the ECG and SCR signals to be used in the automotive real-time emotion recognition systems.

  1. Investigating Irregularly Patterned Deep Brain Stimulation Signal Design Using Biophysical Models

    Directory of Open Access Journals (Sweden)

    Samantha Rose Summerson

    2015-06-01

    Full Text Available Parkinson’s disease (PD is a neurodegenerative disorder which follows from cell loss of dopaminergic neurons in the substantia nigra pars compacta (SNc, a nucleus in the basal ganglia (BG. Deep brain stimulation (DBS is an electrical therapy that modulates the pathological activity to treat the motor symptoms of PD. Although this therapy is currently used in clinical practice, the sufficient conditions for therapeutic efficacy are unknown. In this work we develop a model of critical motor circuit structures in the brain using biophysical cell models as the base components and then evaluate performance of different DBS signals in this model to perform comparative studies of their efficacy. Biological models are an important tool for gaining insights into neural function and, in this case, serve as effective tools for investigating innovative new DBS paradigms. Experiments were performed using the hemi-parkinsonian rodent model to test the same set of signals, verifying the obedience of the model to physiological trends. We show that antidromic spiking from DBS of the subthalamic nucleus (STN has a significant impact on cortical neural activity, which is frequency dependent and additionally modulated by the regularity of the stimulus pulse train used. Irregular spacing between stimulus pulses, where the amount of variability added is bounded, is shown to increase diversification of response of basal ganglia neurons and reduce entropic noise in cortical neurons, which may be fundamentally important to restoration of information flow in the motor circuit.

  2. A theoretical signal processing framework for linear diffusion MRI: Implications for parameter estimation and experiment design.

    Science.gov (United States)

    Varadarajan, Divya; Haldar, Justin P

    2017-11-01

    The data measured in diffusion MRI can be modeled as the Fourier transform of the Ensemble Average Propagator (EAP), a probability distribution that summarizes the molecular diffusion behavior of the spins within each voxel. This Fourier relationship is potentially advantageous because of the extensive theory that has been developed to characterize the sampling requirements, accuracy, and stability of linear Fourier reconstruction methods. However, existing diffusion MRI data sampling and signal estimation methods have largely been developed and tuned without the benefit of such theory, instead relying on approximations, intuition, and extensive empirical evaluation. This paper aims to address this discrepancy by introducing a novel theoretical signal processing framework for diffusion MRI. The new framework can be used to characterize arbitrary linear diffusion estimation methods with arbitrary q-space sampling, and can be used to theoretically evaluate and compare the accuracy, resolution, and noise-resilience of different data acquisition and parameter estimation techniques. The framework is based on the EAP, and makes very limited modeling assumptions. As a result, the approach can even provide new insight into the behavior of model-based linear diffusion estimation methods in contexts where the modeling assumptions are inaccurate. The practical usefulness of the proposed framework is illustrated using both simulated and real diffusion MRI data in applications such as choosing between different parameter estimation methods and choosing between different q-space sampling schemes. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Design, Development and Implementation of the IR Signalling Techniques for Monitoring Ambient and Body Temperature in WBANs

    Directory of Open Access Journals (Sweden)

    Attiya Baqai

    2014-07-01

    Full Text Available Healthcare systems such as hospitals, homecare, telemedicine, and physical rehabilitation are expected to be revolutionized by WBAN (Wireless Body Area Networks. This research work aims to investigate, design, optimize, and demonstrate the applications of IR (Infra-Red communication systems in WBAN. It is aimed to establish a prototype WBAN system capable of measuring Ambient and Body Temperature using LM35 as temperature sensor and transmitting and receiving the data using optical signals. The corresponding technical challenges that have to be faced are also discussed in this paper. Investigations are carried out to efficiently design the hardware using low-cost and low power optical transceivers. The experimental results reveal the successful transmission and reception of Ambient and Body Temperatures over short ranges i.e. up to 3-4 meters. A simple IR transceiver with an LED (Light Emitting Diodes, TV remote control IC and Arduino microcontroller is designed to perform the transmission with sufficient accuracy and ease. Experiments are also performed to avoid interference from other sources like AC and TV remote control signals by implementing IR tags

  4. Neural signal processing and closed-loop control algorithm design for an implanted neural recording and stimulation system.

    Science.gov (United States)

    Hamilton, Lei; McConley, Marc; Angermueller, Kai; Goldberg, David; Corba, Massimiliano; Kim, Louis; Moran, James; Parks, Philip D; Sang Chin; Widge, Alik S; Dougherty, Darin D; Eskandar, Emad N

    2015-08-01

    A fully autonomous intracranial device is built to continually record neural activities in different parts of the brain, process these sampled signals, decode features that correlate to behaviors and neuropsychiatric states, and use these features to deliver brain stimulation in a closed-loop fashion. In this paper, we describe the sampling and stimulation aspects of such a device. We first describe the signal processing algorithms of two unsupervised spike sorting methods. Next, we describe the LFP time-frequency analysis and feature derivation from the two spike sorting methods. Spike sorting includes a novel approach to constructing a dictionary learning algorithm in a Compressed Sensing (CS) framework. We present a joint prediction scheme to determine the class of neural spikes in the dictionary learning framework; and, the second approach is a modified OSort algorithm which is implemented in a distributed system optimized for power efficiency. Furthermore, sorted spikes and time-frequency analysis of LFP signals can be used to generate derived features (including cross-frequency coupling, spike-field coupling). We then show how these derived features can be used in the design and development of novel decode and closed-loop control algorithms that are optimized to apply deep brain stimulation based on a patient's neuropsychiatric state. For the control algorithm, we define the state vector as representative of a patient's impulsivity, avoidance, inhibition, etc. Controller parameters are optimized to apply stimulation based on the state vector's current state as well as its historical values. The overall algorithm and software design for our implantable neural recording and stimulation system uses an innovative, adaptable, and reprogrammable architecture that enables advancement of the state-of-the-art in closed-loop neural control while also meeting the challenges of system power constraints and concurrent development with ongoing scientific research designed

  5. Design of Low Power Algorithms for Automatic Embedded Analysis of Patch ECG Signals

    DEFF Research Database (Denmark)

    Saadi, Dorthe Bodholt

    , several different cable-free wireless patch-type ECG recorders have recently reached the market. One of these recorders is the ePatch designed by the Danish company DELTA. The extended monitoring period available with the patch recorders has demonstrated to increase the diagnostic yield of outpatient ECG....... Such algorithms could allow the real-time transmission of clinically relevant information to a central monitoring station. The first step in embedded ECG interpretation is the automatic detection of each individual heartbeat. An important part of this project was therefore to design a novel algorithm...

  6. Sliding-Mode Control Design of a Boost-Buck Switching Converter for AC Signal Generation

    OpenAIRE

    Biel Solé, Domingo; Guinjoan Gispert, Francisco; Fossas Colet, Enric; Chavarría Roé, Javier

    2004-01-01

    This paper presents a sliding-mode control design of a boost–buck switching converter for a voltage step-up dc–ac conversion without the use of any transformer. This approach combines the step-up/step-down conversion ratio capability of the converter with the robustness properties of sliding-mode control. The proposed control strategy is based on the design of two slidingcontrol laws, one ensuring the control of a full-bridge buck converter for proper dc–ac conversion, and the other one the c...

  7. Architectural design for a low cost FPGA-based traffic signal detection system in vehicles

    Science.gov (United States)

    López, Ignacio; Salvador, Rubén; Alarcón, Jaime; Moreno, Félix

    2007-05-01

    In this paper we propose an architecture for an embedded traffic signal detection system. Development of Advanced Driver Assistance Systems (ADAS) is one of the major trends of research in automotion nowadays. Examples of past and ongoing projects in the field are CHAMELEON ("Pre-Crash Application all around the vehicle" IST 1999-10108), PREVENT (Preventive and Active Safety Applications, FP6-507075, http://www.prevent-ip.org/) and AVRT in the US (Advanced Vision-Radar Threat Detection (AVRT): A Pre-Crash Detection and Active Safety System). It can be observed a major interest in systems for real-time analysis of complex driving scenarios, evaluating risk and anticipating collisions. The system will use a low cost CCD camera on the dashboard facing the road. The images will be processed by an Altera Cyclone family FPGA. The board does median and Sobel filtering of the incoming frames at PAL rate, and analyzes them for several categories of signals. The result is conveyed to the driver. The scarce resources provided by the hardware require an architecture developed for optimal use. The system will use a combination of neural networks and an adapted blackboard architecture. Several neural networks will be used in sequence for image analysis, by reconfiguring a single, generic hardware neural network in the FPGA. This generic network is optimized for speed, in order to admit several executions within the frame rate. The sequence will follow the execution cycle of the blackboard architecture. The global, blackboard architecture being developed and the hardware architecture for the generic, reconfigurable FPGA perceptron will be explained in this paper. The project is still at an early stage. However, some hardware implementation results are already available and will be offered in the paper.

  8. Design and implementation of a reconfigurable mixed-signal SoC based on field programmable analog arrays

    Science.gov (United States)

    Liu, Lintao; Gao, Yuhan; Deng, Jun

    2017-11-01

    This work presents a reconfigurable mixed-signal system-on-chip (SoC), which integrates switched-capacitor-based field programmable analog arrays (FPAA), analog-to-digital converter (ADC), digital-to-analog converter, digital down converter , digital up converter, 32-bit reduced instruction-set computer central processing unit (CPU) and other digital IPs on a single chip with 0.18 μm CMOS technology. The FPAA intellectual property could be reconfigured as different function circuits, such as gain amplifier, divider, sine generator, and so on. This single-chip integrated mixed-signal system is a complete modern signal processing system, occupying a die area of 7 × 8 mm 2 and consuming 719 mW with a clock frequency of 150 MHz for CPU and 200 MHz for ADC/DAC. This SoC chip can help customers to shorten design cycles, save board area, reduce the system power consumption and depress the system integration risk, which would afford a big prospect of application for wireless communication. Project supported by the National High Technology and Development Program of China (No. 2012AA012303).

  9. The incredible shrinking dewlap: signal size, skin elasticity, and mechanical design in the green anole lizard (Anolis carolinensis).

    Science.gov (United States)

    Lailvaux, Simon P; Leifer, Jack; Kircher, Bonnie K; Johnson, Michele A

    2015-10-01

    The expression of male secondary sexual traits can be dynamic, changing size, shape, color, or structure over the course of different seasons. However, the factors underlying such changes are poorly understood. In male Anolis carolinensis lizards, a morphological secondary sexual signal called the dewlap changes size seasonally within individuals. Here, we test the hypothesis that seasonal changes in male dewlap size are driven by increased use and extension of the dewlap in spring and summer, when males are breeding, relative to the winter and fall. We captured male green anole lizards prior to the onset of breeding and constrained the dewlap in half of them such that it could not be extended. We then measured dewlap area in the spring, summer, and winter, and dewlap skin and belly skin elasticity in summer and winter. Dewlaps in unconstrained males increase in area from spring to summer and then shrink in the winter, whereas the dewlaps of constrained males consistently shrink from spring to winter. Dewlap skin is significantly more elastic than belly skin, and skin overall is more elastic in the summer relative to winter. These results show that seasonal changes in dewlap size are a function of skin elasticity and display frequency, and suggest that the mechanical properties of signaling structures can have important implications for signal evolution and design.

  10. Computer-animated stimuli to measure motion sensitivity: constraints on signal design in the Jacky dragon.

    Science.gov (United States)

    Woo, Kevin L; Rieucau, Guillaume; Burke, Darren

    2017-02-01

    Identifying perceptual thresholds is critical for understanding the mechanisms that underlie signal evolution. Using computer-animated stimuli, we examined visual speed sensitivity in the Jacky dragon Amphibolurus muricatus , a species that makes extensive use of rapid motor patterns in social communication. First, focal lizards were tested in discrimination trials using random-dot kinematograms displaying combinations of speed, coherence, and direction. Second, we measured subject lizards' ability to predict the appearance of a secondary reinforcer (1 of 3 different computer-generated animations of invertebrates: cricket, spider, and mite) based on the direction of movement of a field of drifting dots by following a set of behavioural responses (e.g., orienting response, latency to respond) to our virtual stimuli. We found an effect of both speed and coherence, as well as an interaction between these 2 factors on the perception of moving stimuli. Overall, our results showed that Jacky dragons have acute sensitivity to high speeds. We then employed an optic flow analysis to match the performance to ecologically relevant motion. Our results suggest that the Jacky dragon visual system may have been shaped to detect fast motion. This pre-existing sensitivity may have constrained the evolution of conspecific displays. In contrast, Jacky dragons may have difficulty in detecting the movement of ambush predators, such as snakes and of some invertebrate prey. Our study also demonstrates the potential of the computer-animated stimuli technique for conducting nonintrusive tests to explore motion range and sensitivity in a visually mediated species.

  11. Design and implementation of multi-signal and time-varying neural reconstructions.

    Science.gov (United States)

    Nanda, Sumit; Chen, Hanbo; Das, Ravi; Bhattacharjee, Shatabdi; Cuntz, Hermann; Torben-Nielsen, Benjamin; Peng, Hanchuan; Cox, Daniel N; De Schutter, Erik; Ascoli, Giorgio A

    2018-01-23

    Several efficient procedures exist to digitally trace neuronal structure from light microscopy, and mature community resources have emerged to store, share, and analyze these datasets. In contrast, the quantification of intracellular distributions and morphological dynamics is not yet standardized. Current widespread descriptions of neuron morphology are static and inadequate for subcellular characterizations. We introduce a new file format to represent multichannel information as well as an open-source Vaa3D plugin to acquire this type of data. Next we define a novel data structure to capture morphological dynamics, and demonstrate its application to different time-lapse experiments. Importantly, we designed both innovations as judicious extensions of the classic SWC format, thus ensuring full back-compatibility with popular visualization and modeling tools. We then deploy the combined multichannel/time-varying reconstruction system on developing neurons in live Drosophila larvae by digitally tracing fluorescently labeled cytoskeletal components along with overall dendritic morphology as they changed over time. This same design is also suitable for quantifying dendritic calcium dynamics and tracking arbor-wide movement of any subcellular substrate of interest.

  12. New trends in design and fabrication of signal and power cables to increase nuclear safety

    International Nuclear Information System (INIS)

    Salmen, Florin; Florescu, Gheorghe; Ionescu, Aurel

    2007-01-01

    Based on NPP operating experiences in the past, it was found that the inadequate management of aging degradation caused shortening of the lifetime of equipment, which in turn, hindered plant life extension. Aging degradation of plant structures and components should be properly managed to ensure the designated safety function of plant systems during design life and extended life. From a safety perspective, aging management means maintaining the aging degradation level in major equipment and structures below the allowable limit and holding the capacity to sustain abnormal operating condition. Cable aging was not considered as a significant factor in relation to the nuclear power plant maintenance due to its long life which is almost the same as the plant design life. Attempts to extend the lifetime of NPP has become one of the major concern in the nuclear industry world wide. Consequently, life evaluation and lifetime management of cables to survive over 40 years has become major topic of discussion. In connection to this, accelerated aging must be studied in detail in order to simulate the natural aging in NPP. Test results for evaluating aging degradation after accelerated aging of polyethylene jacket will be described herein.There are hundred types of cables in NPPs. These cables can be classified as medium/low voltage cable, low power cable, instrument and control cable, panel connect line cable, special cable, security line cable, phone line cable and ground cable. Insulation and jacket material in electrical cables are fabricated of polymer materials combined with a number of additives and filler to provide the required mechanical, electrical and fire retardant proprieties. The most commonly used insulation materials are XLPE/EPR/EPDM and PVC. PVC has been widely used as an insulation material, particularly in old plants, but it is less used in modern plants. Neoprene/CSPE/PVC are commonly used material for nuclear cable jacket. The old types of cables

  13. Design of Meter-Scale Antenna and Signal Detection System for Underground Magnetic Resonance Sounding in Mines.

    Science.gov (United States)

    Yi, Xiaofeng; Zhang, Jian; Fan, Tiehu; Tian, Baofeng; Jiang, Chuandong

    2018-03-13

    Magnetic resonance sounding (MRS) is a novel geophysical method to detect groundwater directly. By applying this method to underground projects in mines and tunnels, warning information can be provided on water bodies that are hidden in front prior to excavation and thus reduce the risk of casualties and accidents. However, unlike its application to ground surfaces, the application of MRS to underground environments is constrained by the narrow space, quite weak MRS signal, and complex electromagnetic interferences with high intensities in mines. Focusing on the special requirements of underground MRS (UMRS) detection, this study proposes the use of an antenna with different turn numbers, which employs a separated transmitter and receiver. We designed a stationary coil with stable performance parameters and with a side length of 2 m, a matching circuit based on a Q-switch and a multi-stage broad/narrowband mixed filter that can cancel out most electromagnetic noise. In addition, noises in the pass-band are further eliminated by adopting statistical criteria and harmonic modeling and stacking, all of which together allow weak UMRS signals to be reliably detected. Finally, we conducted a field case study of the UMRS measurement in the Wujiagou Mine in Shanxi Province, China, with known water bodies. Our results show that the method proposed in this study can be used to obtain UMRS signals in narrow mine environments, and the inverted hydrological information generally agrees with the actual situation. Thus, we conclude that the UMRS method proposed in this study can be used for predicting hazardous water bodies at a distance of 7-9 m in front of the wall for underground mining projects.

  14. Design of Meter-Scale Antenna and Signal Detection System for Underground Magnetic Resonance Sounding in Mines

    Directory of Open Access Journals (Sweden)

    Xiaofeng Yi

    2018-03-01

    Full Text Available Magnetic resonance sounding (MRS is a novel geophysical method to detect groundwater directly. By applying this method to underground projects in mines and tunnels, warning information can be provided on water bodies that are hidden in front prior to excavation and thus reduce the risk of casualties and accidents. However, unlike its application to ground surfaces, the application of MRS to underground environments is constrained by the narrow space, quite weak MRS signal, and complex electromagnetic interferences with high intensities in mines. Focusing on the special requirements of underground MRS (UMRS detection, this study proposes the use of an antenna with different turn numbers, which employs a separated transmitter and receiver. We designed a stationary coil with stable performance parameters and with a side length of 2 m, a matching circuit based on a Q-switch and a multi-stage broad/narrowband mixed filter that can cancel out most electromagnetic noise. In addition, noises in the pass-band are further eliminated by adopting statistical criteria and harmonic modeling and stacking, all of which together allow weak UMRS signals to be reliably detected. Finally, we conducted a field case study of the UMRS measurement in the Wujiagou Mine in Shanxi Province, China, with known water bodies. Our results show that the method proposed in this study can be used to obtain UMRS signals in narrow mine environments, and the inverted hydrological information generally agrees with the actual situation. Thus, we conclude that the UMRS method proposed in this study can be used for predicting hazardous water bodies at a distance of 7–9 m in front of the wall for underground mining projects.

  15. Designing informative warning signals: Effects of indicator type, modality, and task demand on recognition speed and accuracy

    Science.gov (United States)

    Stevens, Catherine J.; Brennan, David; Petocz, Agnes; Howell, Clare

    2009-01-01

    An experiment investigated the assumption that natural indicators which exploit existing learned associations between a signal and an event make more effective warnings than previously unlearned symbolic indicators. Signal modality (visual, auditory) and task demand (low, high) were also manipulated. Warning effectiveness was indexed by accuracy and reaction time (RT) recorded during training and dual task test phases. Thirty-six participants were trained to recognize 4 natural and 4 symbolic indicators, either visual or auditory, paired with critical incidents from an aviation context. As hypothesized, accuracy was greater and RT was faster in response to natural indicators during the training phase. This pattern of responding was upheld in test phase conditions with respect to accuracy but observed in RT only in test phase conditions involving high demand and the auditory modality. Using the experiment as a specific example, we argue for the importance of considering the cognitive contribution of the user (viz., prior learned associations) in the warning design process. Drawing on semiotics and cognitive psychology, we highlight the indexical nature of so-called auditory icons or natural indicators and argue that the cogniser is an indispensable element in the tripartite nature of signification. PMID:20523852

  16. The singular value filter: a general filter design strategy for PCA-based signal separation in medical ultrasound imaging.

    Science.gov (United States)

    Mauldin, F William; Lin, Dan; Hossack, John A

    2011-11-01

    A general filtering method, called the singular value filter (SVF), is presented as a framework for principal component analysis (PCA) based filter design in medical ultrasound imaging. The SVF approach operates by projecting the original data onto a new set of bases determined from PCA using singular value decomposition (SVD). The shape of the SVF weighting function, which relates the singular value spectrum of the input data to the filtering coefficients assigned to each basis function, is designed in accordance with a signal model and statistical assumptions regarding the underlying source signals. In this paper, we applied SVF for the specific application of clutter artifact rejection in diagnostic ultrasound imaging. SVF was compared to a conventional PCA-based filtering technique, which we refer to as the blind source separation (BSS) method, as well as a simple frequency-based finite impulse response (FIR) filter used as a baseline for comparison. The performance of each filter was quantified in simulated lesion images as well as experimental cardiac ultrasound data. SVF was demonstrated in both simulation and experimental results, over a wide range of imaging conditions, to outperform the BSS and FIR filtering methods in terms of contrast-to-noise ratio (CNR) and motion tracking performance. In experimental mouse heart data, SVF provided excellent artifact suppression with an average CNR improvement of 1.8 dB with over 40% reduction in displacement tracking error. It was further demonstrated from simulation and experimental results that SVF provided superior clutter rejection, as reflected in larger CNR values, when filtering was achieved using complex pulse-echo received data and non-binary filter coefficients.

  17. Design of an adaptive CubeSat transmitter for achieving optimum signal-to-noise ratio (SNR)

    Science.gov (United States)

    Jaswar, F. D.; Rahman, T. A.; Hindia, M. N.; Ahmad, Y. A.

    2017-12-01

    CubeSat technology has opened the opportunity to conduct space-related researches at a relatively low cost. Typical approach to maintain an affordable cubeSat mission is to use a simple communication system, which is based on UHF link with fixed-transmit power and data rate. However, CubeSat in the Low Earth Orbit (LEO) does not have relative motion with the earth rotation, resulting in variable propagation path length that affects the transmission signal. A transmitter with adaptive capability to select multiple sets of data rate and radio frequency (RF) transmit power is proposed to improve and optimise the link. This paper presents the adaptive UHF transmitter design as a solution to overcome the variability of the propagation path. The transmitter output power is adjustable from 0.5W to 2W according to the mode of operations and satellite power limitations. The transmitter is designed to have four selectable modes to achieve the optimum signal-to-noise ratio (SNR) and efficient power consumption based on the link budget analysis and satellite requirement. Three prototypes are developed and tested for space-environment conditions such as the radiation test. The Total Ionizing Dose measurements are conducted in the radiation test done at Malaysia Nuclear Agency Laboratory. The results from this test have proven that the adaptive transmitter can perform its operation with estimated more than seven months in orbit. This radiation test using gamma source with 1.5krad exposure is the first one conducted for a satellite program in Malaysia.

  18. Small signal audio design

    CERN Document Server

    Self, Douglas

    2014-01-01

    Learn to use inexpensive and readily available parts to obtain state-of-the-art performance in all the vital parameters of noise, distortion, crosstalk and so on. With ample coverage of preamplifiers and mixers and a new chapter on headphone amplifiers, this practical handbook provides an extensive repertoire of circuits that can be put together to make almost any type of audio system.A resource packed full of valuable information, with virtually every page revealing nuggets of specialized knowledge not found elsewhere. Essential points of theory that bear on practical performance are lucidly

  19. Theoretical basis, principles of design, and experimental study of the prototype of perfect AFCS transmitting signals without coding

    Science.gov (United States)

    Platonov, A.; Zaitsev, Ie.; Opalski, L. J.

    2017-08-01

    The paper presents an overview of design methodology and results of experiments with a Prototype of highly efficient optimal adaptive feedback communication systems (AFCS), transmitting low frequency analog signals without coding. The paper emphasizes the role of the forward transmitter saturation as the factor that blocked implementation of theoretical results of pioneer (1960-1970s) and later research on FCS. Deepened analysis of the role of statistical fitting condition in adequate formulation and solution of AFCS optimization task is given. Solution of the task - optimal transmission/reception algorithms is presented in the form useful for elaboration of the hardware/software Prototype. A notable particularity of the Prototype is absence of the encoding/decoding units, whose functions are realized by the adaptive pulse amplitude modulator (PAM) of the forward transmitter (FT) and estimating/controlling algorithm in the receiver of base station (BS). Experiments confirm that the Prototype transmits signals from FT to BS "perfectly": with the bit rate equal to the capacity of the system, and with limit energy [J/bit] and spectral [bps/Hz] efficiency. Another, not less important and confirmed experimentally, particularity of AFCS is its capability to adjust parameters of FT and BS to the characteristics of scenario of application and maintain the ideal regime of transmission including spectralenergy efficiency. AFCS adjustment can be made using BS estimates of mean square error (MSE). The concluding part of the paper contains discussion of the presented results, stressing capability of AFCS to solve problems appearing in development of dense wireless networks.

  20. Relevancies of multiple-interaction events and signal-to-noise ratio for Anger-logic based PET detector designs

    Science.gov (United States)

    Peng, Hao

    2015-10-01

    A fundamental challenge for PET block detector designs is to deploy finer crystal elements while limiting the number of readout channels. The standard Anger-logic scheme including light sharing (an 8 by 8 crystal array coupled to a 2×2 photodetector array with an optical diffuser, multiplexing ratio: 16:1) has been widely used to address such a challenge. Our work proposes a generalized model to study the impacts of two critical parameters on spatial resolution performance of a PET block detector: multiple interaction events and signal-to-noise ratio (SNR). The study consists of the following three parts: (1) studying light output profile and multiple interactions of 511 keV photons within crystal arrays of different crystal widths (from 4 mm down to 1 mm, constant height: 20 mm); (2) applying the Anger-logic positioning algorithm to investigate positioning/decoding uncertainties (i.e., "block effect") in terms of peak-to-valley ratio (PVR), with light sharing, multiple interactions and photodetector SNR taken into account; and (3) studying the dependency of spatial resolution on SNR in the context of modulation transfer function (MTF). The proposed model can be used to guide the development and evaluation of a standard Anger-logic based PET block detector including: (1) selecting/optimizing the configuration of crystal elements for a given photodetector SNR; and (2) predicting to what extent additional electronic multiplexing may be implemented to further reduce the number of readout channels.

  1. An investigation of signal performance enhancements achieved through innovative pixel design across several generations of indirect detection, active matrix, flat-panel arrays

    International Nuclear Information System (INIS)

    Antonuk, Larry E.; Zhao Qihua; El-Mohri, Youcef; Du Hong; Wang Yi; Street, Robert A.; Ho, Jackson; Weisfield, Richard; Yao, William

    2009-01-01

    Active matrix flat-panel imager (AMFPI) technology is being employed for an increasing variety of imaging applications. An important element in the adoption of this technology has been significant ongoing improvements in optical signal collection achieved through innovations in indirect detection array pixel design. Such improvements have a particularly beneficial effect on performance in applications involving low exposures and/or high spatial frequencies, where detective quantum efficiency is strongly reduced due to the relatively high level of additive electronic noise compared to signal levels of AMFPI devices. In this article, an examination of various signal properties, as determined through measurements and calculations related to novel array designs, is reported in the context of the evolution of AMFPI pixel design. For these studies, dark, optical, and radiation signal measurements were performed on prototype imagers incorporating a variety of increasingly sophisticated array designs, with pixel pitches ranging from 75 to 127 μm. For each design, detailed measurements of fundamental pixel-level properties conducted under radiographic and fluoroscopic operating conditions are reported and the results are compared. A series of 127 μm pitch arrays employing discrete photodiodes culminated in a novel design providing an optical fill factor of ∼80% (thereby assuring improved x-ray sensitivity), and demonstrating low dark current, very low charge trapping and charge release, and a large range of linear signal response. In two of the designs having 75 and 90 μm pitches, a novel continuous photodiode structure was found to provide fill factors that approach the theoretical maximum of 100%. Both sets of novel designs achieved large fill factors by employing architectures in which some, or all of the photodiode structure was elevated above the plane of the pixel addressing transistor. Generally, enhancement of the fill factor in either discrete or continuous

  2. Pilot signal design via constrained optimization with application to delay-Doppler shift estimation in OFDM systems

    DEFF Research Database (Denmark)

    Jing, Lishuai; Pedersen, Troels; Fleury, Bernard Henri

    2013-01-01

    for which we propose a genetic algorithm that computes close-to-optimal solutions. Simulation results demonstrate that the proposed algorithm can efficiently find pilot signals that outperform the state-of-the-art pilot signals in both single-path and multipath propagation scenarios. In addition, we...

  3. Concept and design of a UAS-based platform for measurements of RF signal-in-space

    Science.gov (United States)

    Schrader, Thorsten; Bredemeyer, Jochen; Mihalachi, Marius; Rohde, Jan; Kleine-Ostmann, Thomas

    2016-09-01

    Field strength or signal-in-space (SIS) measurements have been performed by using manned helicopters, aircrafts or from ground level using extendable masts. With the availability of unmanned aerial systems (UAS) such as multicopters a new versatile platform for SIS measurements is deployable. Larger types show up to eight individually driven electric motors and controllers (therefore called octocopter). They provide the ability to fly along predefined traces, to hover at waypoints and to initiate other actions when those have been reached. They provide self-levelling and stabilisation and moreover, they may gear at a point of interest regardless of their actual position, e.g. during their flight around a tower. Their payload mainly depends on the platform size and allows integration of complex measurement equipment. Upgrading their navigation capabilities including state-of-the-art global navigation satellite system (GNSS) and ground station transmitter (real-time kinematic - RTK) enables precise localisation of the UAS. For operation in electromagnetic harsh environments a shielding can be considered and integrated into the concept. This paper describes concept and design of an octocopter and its instrumentation, along with applications in recent projects, in which we measure and validate terrestrial navigation systems applied in air traffic and the weather forecast services. Among those are instrumentation landing systems (ILS), VHF omnidirectional radio ranges (VOR), airport traffic and weather radars as well as military surveillance radars, and UHF wind profilers. Especially to investigate the possible interaction of VORs and radars with single wind turbines (WT) or wind power plants has become a major request of economy, military and politics. Here, UAS can be deployed to deliver measurement data investigating this interaction. Once developed and setup to a certain extent, UAS are easy and cost-efficient to operate. Nonetheless, due to their compact size, UAS

  4. Design and array signal suggestion of array type pulsed eddy current probe for health monitoring of metal tubes

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Young Kil [Dept. of Electrical Engineering, Kunsan National University, Kunsan (Korea, Republic of)

    2015-10-15

    An array type probe for monitoring metal tubes is proposed in this paper which utilizes peak value and peak time of a pulsed eddy current(PEC) signal. The probe consists of an array of encircling coils along a tube and the outside of coils is shielded by ferrite to prevent source magnetic fields from directly affecting sensor signals since it is the magnetic fields produced by eddy currents that reflect the condition of metal tubes. The positions of both exciter and sensor coils are consecutively moved automatically so that manual scanning is not necessary. At one position of send-receive coils, peak value and peak time are extracted from a sensor PEC signal and these data are accumulated for all positions to form an array type peak value signal and an array type peak time signal. Numerical simulation was performed using the backward difference method in time and the finite element method for spatial analysis. Simulation results showed that peak value increases and the peak appears earlier as the defect depth or length increases. The proposed array signals are shown to be excellent in reflecting the defect location as well as variations of defect depth and length within the array probe.

  5. Signal Processing

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Signal processing techniques, extensively used nowadays to maximize the performance of audio and video equipment, have been a key part in the design of hardware and software for high energy physics detectors since pioneering applications in the UA1 experiment at CERN in 1979

  6. Pedestrian Safety Treatments for Signalized Intersections : Training Course Development

    Science.gov (United States)

    2017-11-01

    When drivers make left turns during a permissive turn phase, they must yield to pedestrians as well as oncoming through vehicles. Left-turning drivers sometimes overlook pedestrians in the crosswalk while watching the opposing intersection approach. ...

  7. Virtual instrumentation technique used in the nuclear digital signal processing system design: Energy and time measurement tests

    International Nuclear Information System (INIS)

    Pechousek, J.; Prochazka, R.; Prochazka, V.; Frydrych, J.

    2011-01-01

    In this report, computer-based digital signal processing system with a 200 MS s -1 sampling digitizer is presented. Virtual instrumentation technique is used to easily develop a system which provides spectroscopy measurements such as amplitude and time signal analysis, with the time-of-flight facility. Several test measurements were performed to determine the characteristics of a system. The presented system may find its application in the coincidence measurement since the system is usable for different types of detectors and sensitive to decay lifetimes from tens of nanoseconds to seconds.

  8. Design of Embedded System for Multivariate Classification of Finger and Thumb Movements Using EEG Signals for Control of Upper Limb Prosthesis

    Science.gov (United States)

    Javed, Amna; Tiwana, Mohsin I.; Khan, Umar Shahbaz

    2018-01-01

    Brain Computer Interface (BCI) determines the intent of the user from a variety of electrophysiological signals. These signals, Slow Cortical Potentials, are recorded from scalp, and cortical neuronal activity is recorded by implanted electrodes. This paper is focused on design of an embedded system that is used to control the finger movements of an upper limb prosthesis using Electroencephalogram (EEG) signals. This is a follow-up of our previous research which explored the best method to classify three movements of fingers (thumb movement, index finger movement, and first movement). Two-stage logistic regression classifier exhibited the highest classification accuracy while Power Spectral Density (PSD) was used as a feature of the filtered signal. The EEG signal data set was recorded using a 14-channel electrode headset (a noninvasive BCI system) from right-handed, neurologically intact volunteers. Mu (commonly known as alpha waves) and Beta Rhythms (8–30 Hz) containing most of the movement data were retained through filtering using “Arduino Uno” microcontroller followed by 2-stage logistic regression to obtain a mean classification accuracy of 70%. PMID:29888252

  9. Design of Embedded System for Multivariate Classification of Finger and Thumb Movements Using EEG Signals for Control of Upper Limb Prosthesis

    Directory of Open Access Journals (Sweden)

    Nasir Rashid

    2018-01-01

    Full Text Available Brain Computer Interface (BCI determines the intent of the user from a variety of electrophysiological signals. These signals, Slow Cortical Potentials, are recorded from scalp, and cortical neuronal activity is recorded by implanted electrodes. This paper is focused on design of an embedded system that is used to control the finger movements of an upper limb prosthesis using Electroencephalogram (EEG signals. This is a follow-up of our previous research which explored the best method to classify three movements of fingers (thumb movement, index finger movement, and first movement. Two-stage logistic regression classifier exhibited the highest classification accuracy while Power Spectral Density (PSD was used as a feature of the filtered signal. The EEG signal data set was recorded using a 14-channel electrode headset (a noninvasive BCI system from right-handed, neurologically intact volunteers. Mu (commonly known as alpha waves and Beta Rhythms (8–30 Hz containing most of the movement data were retained through filtering using “Arduino Uno” microcontroller followed by 2-stage logistic regression to obtain a mean classification accuracy of 70%.

  10. Design of Embedded System for Multivariate Classification of Finger and Thumb Movements Using EEG Signals for Control of Upper Limb Prosthesis.

    Science.gov (United States)

    Rashid, Nasir; Iqbal, Javaid; Javed, Amna; Tiwana, Mohsin I; Khan, Umar Shahbaz

    2018-01-01

    Brain Computer Interface (BCI) determines the intent of the user from a variety of electrophysiological signals. These signals, Slow Cortical Potentials, are recorded from scalp, and cortical neuronal activity is recorded by implanted electrodes. This paper is focused on design of an embedded system that is used to control the finger movements of an upper limb prosthesis using Electroencephalogram (EEG) signals. This is a follow-up of our previous research which explored the best method to classify three movements of fingers (thumb movement, index finger movement, and first movement). Two-stage logistic regression classifier exhibited the highest classification accuracy while Power Spectral Density (PSD) was used as a feature of the filtered signal. The EEG signal data set was recorded using a 14-channel electrode headset (a noninvasive BCI system) from right-handed, neurologically intact volunteers. Mu (commonly known as alpha waves) and Beta Rhythms (8-30 Hz) containing most of the movement data were retained through filtering using "Arduino Uno" microcontroller followed by 2-stage logistic regression to obtain a mean classification accuracy of 70%.

  11. Design, Construction, and Use of a Single Board Computer Beowulf Cluster: Application of the Small-Footprint, Low-Cost, InSignal 5420 Octa Board

    OpenAIRE

    Cusick, James J.; Miller, William; Laurita, Nicholas; Pitt, Tasha

    2014-01-01

    In recent years development in the area of Single Board Computing has been advancing rapidly. At Wolters Kluwer's Corporate Legal Services Division a prototyping effort was undertaken to establish the utility of such devices for practical and general computing needs. This paper presents the background of this work, the design and construction of a 64 core 96 GHz cluster, and their possibility of yielding approximately 400 GFLOPs from a set of small footprint InSignal boards created for just o...

  12. Design of a ×4 subharmonic sub-millimeter wave diode mixer, based on an analytic expression for small-signal conversion admittance parameters

    DEFF Research Database (Denmark)

    Michaelsen, Rasmus Schandorph; Johansen, Tom Keinicke; Krozer, Viktor

    2013-01-01

    Instead of using frequency multipliers before a fundamental mixer, subharmonic mixers can be used. In order to develop novel subharmonic mixer architectures it is necessary to know the exact signal phase at the nonlinear element. The purpose of this paper is to generalize the description of the s....... With an RF frequency of 640 GHz, this design achieves a conversion gain of −13.5 dB with a LO-power of only −2.5 dBm....

  13. Design of a candidate vibrational signal for mating disruption against the glassy-winged sharpshooter, Homalodisca Vitripennis

    Science.gov (United States)

    The glassy-winged sharpshooter (GWSS), Homalodisca vitripennis, is an important pest of grapevines due to its ability to transmit Xylella fastidiosa, the causal agent of Pierce’s disease. GWSS mating communication is based on vibrational signals; therefore, vibrational mating disruption could be an ...

  14. A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.

    Science.gov (United States)

    Hu, Jianxin; Stern, Matthew; Gimenez, Luis E; Wanka, Lizzy; Zhu, Lu; Rossi, Mario; Meister, Jaroslawna; Inoue, Asuka; Beck-Sickinger, Annette G; Gurevich, Vsevolod V; Wess, Jürgen

    2016-04-08

    Designerreceptorsexclusivelyactivated by adesignerdrug (DREADDs) are clozapine-N-oxide-sensitive designer G protein-coupled receptors (GPCRs) that have emerged as powerful novel chemogenetic tools to study the physiological relevance of GPCR signaling pathways in specific cell types or tissues. Like endogenous GPCRs, clozapine-N-oxide-activated DREADDs do not only activate heterotrimeric G proteins but can also trigger β-arrestin-dependent (G protein-independent) signaling. To dissect the relative physiological relevance of G protein-mediatedversusβ-arrestin-mediated signaling in different cell types or physiological processes, the availability of G protein- and β-arrestin-biased DREADDs would be highly desirable. In this study, we report the development of a mutationally modified version of a non-biased DREADD derived from the M3muscarinic receptor that can activate Gq/11with high efficacy but lacks the ability to interact with β-arrestins. We also demonstrate that this novel DREADD is activein vivoand that cell type-selective expression of this new designer receptor can provide novel insights into the physiological roles of G protein (Gq/11)-dependentversusβ-arrestin-dependent signaling in hepatocytes. Thus, this novel Gq/11-biased DREADD represents a powerful new tool to study the physiological relevance of Gq/11-dependent signaling in distinct tissues and cell types, in the absence of β-arrestin-mediated cellular effects. Such studies should guide the development of novel classes of functionally biased ligands that show high efficacy in various pathophysiological conditions but display a reduced incidence of side effects. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Design and Implementation of an Emergency Vehicle Signal Preemption System Based on Cooperative Vehicle-Infrastructure Technology

    OpenAIRE

    Yinsong Wang; Zhizhou Wu; Xiaoguang Yang; Luoyi Huang

    2013-01-01

    Emergency vehicle is an important part of traffic flow. The efficiency, reliability, and safety of emergency vehicle operations dropped due to increasing traffic congestion. With the advancement of the wireless communication technologies and the development of the vehicle-to-vehicle (v2v) and vehicle-to-infrastructure (v2i) systems, called Cooperative Vehicle-Infrastructure System (CVIS), there is an opportunity to provide appropriate traffic signal preemption for emergency vehicle based on r...

  16. Attractor Structures of Signaling Networks: Consequences of Different Conformational Barcode Dynamics and Their Relations to Network-Based Drug Design.

    Science.gov (United States)

    Szalay, Kristóf Z; Nussinov, Ruth; Csermely, Peter

    2014-06-01

    Conformational barcodes tag functional sites of proteins and are decoded by interacting molecules transmitting the incoming signal. Conformational barcodes are modified by all co-occurring allosteric events induced by post-translational modifications, pathogen, drug binding, etc. We argue that fuzziness (plasticity) of conformational barcodes may be increased by disordered protein structures, by integrative plasticity of multi-phosphorylation events, by increased intracellular water content (decreased molecular crowding) and by increased action of molecular chaperones. This leads to increased plasticity of signaling and cellular networks. Increased plasticity is both substantiated by and inducing an increased noise level. Using the versatile network dynamics tool, Turbine (www.turbine.linkgroup.hu), here we show that the 10 % noise level expected in cellular systems shifts a cancer-related signaling network of human cells from its proliferative attractors to its largest, apoptotic attractor representing their health-preserving response in the carcinogen containing and tumor suppressor deficient environment modeled in our study. Thus, fuzzy conformational barcodes may not only make the cellular system more plastic, and therefore more adaptable, but may also stabilize the complex system allowing better access to its largest attractor. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Manipulation of signaling thresholds in "engineered stem cell niches" identifies design criteria for pluripotent stem cell screens.

    Directory of Open Access Journals (Sweden)

    Raheem Peerani

    Full Text Available In vivo, stem cell fate is regulated by local microenvironmental parameters. Governing parameters in this stem cell niche include soluble factors, extra-cellular matrix, and cell-cell interactions. The complexity of this in vivo niche limits analyses into how individual niche parameters regulate stem cell fate. Herein we use mouse embryonic stem cells (mESC and micro-contact printing (microCP to investigate how niche size controls endogenous signaling thresholds. microCP is used to restrict colony diameter, separation, and degree of clustering. We show, for the first time, spatial control over the activation of the Janus kinase/signal transducer and activator of transcription pathway (Jak-Stat. The functional consequences of this niche-size-dependent signaling control are confirmed by demonstrating that direct and indirect transcriptional targets of Stat3, including members of the Jak-Stat pathway and pluripotency-associated genes, are regulated by colony size. Modeling results and empirical observations demonstrate that colonies less than 100 microm in diameter are too small to maximize endogenous Stat3 activation and that colonies separated by more than 400 microm can be considered independent from each other. These results define parameter boundaries for the use of ESCs in screening studies, demonstrate the importance of context in stem cell responsiveness to exogenous cues, and suggest that niche size is an important parameter in stem cell fate control.

  18. Inspection method of cable-stayed bridge using magnetic flux leakage detection: principle, sensor design, and signal processing

    International Nuclear Information System (INIS)

    Xu, Fengyu; Wang, Xingsong; Wu, Hongtao

    2012-01-01

    A nondestructive testing technique based on magnetic flux leakage is presented to inspect automatically the stay cables with large diameters of a cable-stayed bridge. Using the proposed inspection method, an online nondestructive testing (NDT) modular sensor is developed. The wreath-like sensor is composed of several sensor units that embrace the cable at equal angles. Each sensor unit consists of two permanent magnets and a hall sensor to detect the magnetic flux density. The modular sensor can be installed conveniently on cables with various diameters by increasing the number of sensor units and adjusting the relative distances between adjacent sensor units. Results of the experiments performed on a man-made cable with faults prove that the proposed sensor can inspect the status signals of the inner wires of the cables. To filter the interfering signals, three processing algorithms are discussed, including the moving average method, improved detrending algorithm, and signal processing based on a digital filter. Results show that the developed NDT sensor carried by a cable inspection robot can move along the cable and monitor the state of the stay cables

  19. A signal pre-processing algorithm designed for the needs of hardware implementation of neural classifiers used in condition monitoring

    DEFF Research Database (Denmark)

    Dabrowski, Dariusz; Hashemiyan, Zahra; Adamczyk, Jan

    2015-01-01

    Gearboxes have a significant influence on the durability and reliability of a power transmission system. Currently, extensive research studies are being carried out to increase the reliability of gearboxes working in the energy industry, especially with a focus on planetary gears in wind turbines...... is to estimate the features of a vibration signal that are related to failures, e.g. misalignment and unbalance. These features can serve as the components of an input vector for a neural classifier. The approach proposed here has several important benefits: it is resistant to small speed fluctuations up to 7...

  20. Exploring unobserved heterogeneity in bicyclists' red-light running behaviors at different crossing facilities.

    Science.gov (United States)

    Guo, Yanyong; Li, Zhibin; Wu, Yao; Xu, Chengcheng

    2018-06-01

    Bicyclists running the red light at crossing facilities increase the potential of colliding with motor vehicles. Exploring the contributing factors could improve the prediction of running red-light probability and develop countermeasures to reduce such behaviors. However, individuals could have unobserved heterogeneities in running a red light, which make the accurate prediction more challenging. Traditional models assume that factor parameters are fixed and cannot capture the varying impacts on red-light running behaviors. In this study, we employed the full Bayesian random parameters logistic regression approach to account for the unobserved heterogeneous effects. Two types of crossing facilities were considered which were the signalized intersection crosswalks and the road segment crosswalks. Electric and conventional bikes were distinguished in the modeling. Data were collected from 16 crosswalks in urban area of Nanjing, China. Factors such as individual characteristics, road geometric design, environmental features, and traffic variables were examined. Model comparison indicates that the full Bayesian random parameters logistic regression approach is statistically superior to the standard logistic regression model. More red-light runners are predicted at signalized intersection crosswalks than at road segment crosswalks. Factors affecting red-light running behaviors are gender, age, bike type, road width, presence of raised median, separation width, signal type, green ratio, bike and vehicle volume, and average vehicle speed. Factors associated with the unobserved heterogeneity are gender, bike type, signal type, separation width, and bike volume. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. An EM Simulation-Based Design Flow for Custom-Built MR Coils Incorporating Signal and Noise.

    Science.gov (United States)

    Horneff, Andreas; Eder, Michael; Hell, Erich; Ulrici, Johannes; Felder, Jorg; Rasche, Volker; Anders, Jens

    2018-02-01

    Developing custom-built MR coils is a cumbersome task, in which an a priori prediction of the coils' SNR performance, their sensitivity pattern, and their depth of penetration helps to greatly speed up the design process by reducing the required hardware manufacturing iterations. The simulation-based design flow presented in this paper takes the entire MR imaging process into account. That is, it includes all geometric and material properties of the coil and the phantom, the thermal noise as well as the target MR sequences. The proposed simulation-driven design flow is validated using a manufactured prototype coil, whose performance was optimized regarding its SNR performance, based on the presented design flow, by comparing the coil's measured performance against the simulated results. In these experiments, the mean and the standard deviation of the relative error between the simulated and measured coil sensitivity pattern were found to be and . Moreover, the peak deviation between the simulated and measured voxel SNR was found to be less than 4%, indicating that simulations are in good accordance with the measured results, validating the proposed software-based design approach.

  2. The design and validation of a hybrid digital-signal-processing plug-in for traditional cochlear implant speech processors.

    Science.gov (United States)

    Hajiaghababa, Fatemeh; Marateb, Hamid R; Kermani, Saeed

    2018-06-01

    Cochlear implants (CIs) are electronic devices restoring partial hearing to deaf individuals with profound hearing loss. In this paper, a new plug-in for traditional IIR filter-banks (FBs) is presented for cochlear implants based on wavelet neural networks (WNNs). Having provided such a plug-in for commercially available CIs, it is possible not only to use available hardware in the market but also to optimize their performance compared with the-state-of-the-art. An online database of Dutch diphone perception was used in our study. The weights of the WNNs were tuned using particle swarm optimization (PSO) on a training set (speech-shaped noise (SSN) of 2 dB SNR), while its performance was assessed on a test set in terms of objective and composite measures in the hold-out validation framework. The cost function was defined based on the combination of mean square error (MSE), short‑time objective intelligibility (STOI) criteria on the training set. Variety of performance indices were used including segmental signal- to -noise ratio (SNRseg), MSE, STOI, log-likelihood ratio (LLR), weighted spectral slope (WSS), and composite measures C sig , C bak and C ovl . Meanwhile, the following CI speech processing techniques were used for comparison: traditional FBs, dual resonance nonlinear (DRNL) and simple dual path nonlinear (SPDN) models. The average SNRseg, MSE, and LLR values for the WNN in the entire data set were 2.496 ± 2.794, 0.086 ± 0.025 and 2.323 ± 0.281, respectively. The proposed method significantly improved MSE, SNR, SNRseg, LLR, C sig C bak and C ovl compared with the other three methods (repeated-measures analysis of variance (ANOVA); P < 0.05). The average running time of the proposed algorithm (written in Matlab R2013a) on the training and test sets for each consonant or vowel on an Intel dual-core 2.10 GHz CPU with 2GB of RAM was 9.91 ± 0.87 (s) and 0.19 ± 0.01 (s), respectively. The proposed algorithm is accurate and

  3. A mathematical model of heat flow in a thermopile for measuring muscle heat production: implications for design and signal analysis.

    Science.gov (United States)

    Barclay, C J

    2015-09-01

    Contracting muscles produce heat which largely arises from the biochemical reactions that provide the energy for contraction. Measurements of muscle heat production have made, and continue to make, important contributions to our understanding of the bases of contraction. Most measurements of muscle heat production are made using a thermopile, consisting of a series of thermocouples arranged so that alternate thermocouples are in thermal contact with the muscle and with an isothermal reference. In this study, a mathematical model was constructed of a muscle lying on a thermopile consisting of antimony-bismuth thermocouples sandwiched between polymer sheets. The validity of the model was demonstrated by its ability to accurately predict thermopile outputs in response to applying heat to the thermopile surface, to generating heat in the thermocouples using the Peltier effect and to adding heat capacity on the thermopile surface. The model was then used to show how practical changes to thermopile construction could minimise response time and thermopile heat capacity and allow measurement of very low rates of heat production. The impulse response of a muscle-thermopile system was generated using the model and used to illustrate how a measured signal can be deconvolved with the impulse response to correct for lag introduced by the thermopile.

  4. Rational design of DKK3 structure-based small peptides as antagonists of Wnt signaling pathway and in silico evaluation of their efficiency.

    Directory of Open Access Journals (Sweden)

    Mansour Poorebrahim

    Full Text Available Dysregulated Wnt signaling pathway is highly associated with the pathogenesis of several human cancers. Dickkopf proteins (DKKs are thought to inhibit Wnt signaling pathway through binding to lipoprotein receptor-related protein (LRP 5/6. In this study, based on the 3-dimensional (3D structure of DKK3 Cys-rich domain 2 (CRD2, we have designed and developed several peptide inhibitors of Wnt signaling pathway. Modeller 9.15 package was used to predict 3D structure of CRD2 based on the Homology modeling (HM protocol. After refinement and minimization with GalaxyRefine and NOMAD-REF servers, the quality of selected models was evaluated utilizing VADAR, SAVES and ProSA servers. Molecular docking studies as well as literature-based information revealed two distinct boxes located at CRD2 which are actively involved in the DKK3-LRP5/6 interaction. A peptide library was constructed conducting the backrub sequence tolerance scanning protocol in Rosetta3.5 according to the DKK3-LRP5/6 binding sites. Seven tolerated peptides were chosen and their binding affinity and stability were improved by some logical amino acid substitutions. Molecular dynamics (MD simulations of peptide-LRP5/6 complexes were carried out using GROMACS package. After evaluation of binding free energies, stability, electrostatic potential and some physicochemical properties utilizing computational approaches, three peptides (PEP-I1, PEP-I3 and PEP-II2 demonstrated desirable features. However, all seven improved peptides could sufficiently block the Wnt-binding site of LRP6 in silico. In conclusion, we have designed and improved several small peptides based on the LRP6-binding site of CRD2 of DKK3. These peptides are highly capable of binding to LRP6 in silico, and may prevent the formation of active Wnt-LRP6-Fz complex.

  5. Optimal Controller Design of a Wind Turbine with Doubly Fed Induction Generator for Small Signal Stability Enhancement

    DEFF Research Database (Denmark)

    Yang, Lihui; Yang, Guangya; Xu, Zhao

    2010-01-01

    Multi-objective optimal controller design of a doubly fed induction generator (DFIG) wind turbine system using Differential Evolution (DE) is presented in this chapter. A detailed mathematical model of DFIG wind turbine with a close loop vector control system is developed. Based on this, objective...... functions, addressing the steady state stability and dynamic performance at different operating conditions are implemented to optimize the controller parameters of both the rotor and grid side converters. A superior ε-constraint method and method of adaptive penalties are applied to handle the multi...

  6. Design

    DEFF Research Database (Denmark)

    Volf, Mette

    This publication is unique in its demystification and operationalization of the complex and elusive nature of the design process. The publication portrays the designer’s daily work and the creative process, which the designer is a part of. Apart from displaying the designer’s work methods...... and design parameters, the publication shows examples from renowned Danish design firms. Through these examples the reader gets an insight into the designer’s reality....

  7. A 5.2/5.8 GHz Dual Band On-Off Keying Transmitter Design for Bio-Signal Transmission

    Science.gov (United States)

    Wu, Chang-Hsi; You, Hong-Cheng; Huang, Shun-Zhao

    2018-02-01

    An architecture of 5.2/5.8-GHz dual-band on-off keying (DBOOK) modulated transmitter is designed in a 0.18-μm CMOS technology. The proposed DBOOK transmitter is used in the biosignal transmission system with high power efficiency and small area. To reduce power consumption and enhance output swing, two pairs of center-tapped transformers are used as both LC tank and source grounding choke for the designed voltage controlled oscillator (VCO). Switching capacitances are used to achieve dual band operations, and a complemented power combiner is used to merge the differential output power of VCO to a single-ended output. Besides, the linearizer circuits are used in the proposed power amplifier with wideband output matching to improve the linearity both at 5.2/5.8-GHz bands. The designed DBOOK transmitter is implemented by dividing it into two chips. One chip implements the dual-band switching VCO and power combiner, and the other chip implements a linear power amplifier including dual-band operation. The first chip drives an output power of 2.2mW with consuming power of 5.13 mW from 1.1 V supply voltage. With the chip size including pad of 0.61 × 0.91 m2, the measured data rate and transmission efficiency attained are 100 Mb/s and 51 pJ/bit, respectively. The second chip, for power enhanced mode, exhibits P1 dB of -9 dBm, IIP3 of 1 dBm, the output power 1 dB compression point of 12.42 dBm, OIP3 of about 21 dBm, maximum output power of 17.02/16.18 dBm, and power added efficiency of 17.13/16.95% for 5.2/ 5.8 GHz. The chip size including pads is 0:693 × 1:084mm2.

  8. Macrocell Builder: IP-Block-Based Design Environment for High-Throughput VLSI Dedicated Digital Signal Processing Systems

    Directory of Open Access Journals (Sweden)

    Urard Pascal

    2006-01-01

    Full Text Available We propose an efficient IP-block-based design environment for high-throughput VLSI systems. The flow generates SystemC register-transfer-level (RTL architecture, starting from a Matlab functional model described as a netlist of functional IP. The refinement model inserts automatically control structures to manage delays induced by the use of RTL IPs. It also inserts a control structure to coordinate the execution of parallel clocked IP. The delays may be managed by registers or by counters included in the control structure. The flow has been used successfully in three real-world DSP systems. The experimentations show that the approach can produce efficient RTL architecture and allows to save huge amount of time.

  9. Optimal controller design of a doubly fed induction generator wind turbine system for small signal stability enhancement

    DEFF Research Database (Denmark)

    Yang, Lihui; Yang, Guang-Ya; Xu, Zhao

    2010-01-01

    Multi-objective optimal controller design of a doubly-fed induction generator (DFIG) wind turbine system using differential evolution (DE) is presented. A detailed mathematical model of DFIG wind turbine with a closed-loop vector control system is developed. Based on this, objective functions...... and the constraint with DE, respectively. Eigenvalue analysis and time-domain simulations are performed on a single machine infinite bus system as well as a nine-bus multi-machine system with two DFIG wind turbines to illustrate the control performance of the DFIG wind turbine with the optimised controller...... addressing the steady-state stability and dynamic performance at different operating conditions are implemented to optimise the controller parameters of both the rotor and grid-side converters. A superior 1-constraint method and method of adaptive penalties are applied to handle the multi-objective problem...

  10. The newest digital signal processing

    International Nuclear Information System (INIS)

    Lee, Chae Uk

    2002-08-01

    This book deal with the newest digital signal processing, which contains introduction on conception of digital signal processing, constitution and purpose, signal and system such as signal, continuos signal, discrete signal and discrete system, I/O expression on impress response, convolution, mutual connection of system and frequency character,z transform of definition, range, application of z transform and relationship with laplace transform, Discrete fourier, Fast fourier transform on IDFT algorithm and FFT application, foundation of digital filter of notion, expression, types, frequency characteristic of digital filter and design order of filter, Design order of filter, Design of FIR digital filter, Design of IIR digital filter, Adaptive signal processing, Audio signal processing, video signal processing and application of digital signal processing.

  11. A support vector machine designed to identify breasts at high risk using multi-probe generated REIS signals: a preliminary assessment

    Science.gov (United States)

    Gur, David; Zheng, Bin; Lederman, Dror; Dhurjaty, Sreeram; Sumkin, Jules; Zuley, Margarita

    2010-02-01

    A new resonance-frequency based electronic impedance spectroscopy (REIS) system with multi-probes, including one central probe and six external probes that are designed to contact the breast skin in a circular form with a radius of 60 millimeters to the central ("nipple") probe, has been assembled and installed in our breast imaging facility. We are conducting a prospective clinical study to test the performance of this REIS system in identifying younger women (detection of a highly suspicious breast lesion and 50 were determined negative during mammography screening. REIS output signal sweeps that we used to compute an initial feature included both amplitude and phase information representing differences between corresponding (matched) EIS signal values acquired from the left and right breasts. A genetic algorithm was applied to reduce the feature set and optimize a support vector machine (SVM) to classify the REIS examinations into "biopsy recommended" and "non-biopsy" recommended groups. Using the leave-one-case-out testing method, the classification performance as measured by the area under the receiver operating characteristic (ROC) curve was 0.816 +/- 0.042. This pilot analysis suggests that the new multi-probe-based REIS system could potentially be used as a risk stratification tool to identify pre-screened young women who are at higher risk of having or developing breast cancer.

  12. Design and implementation of an integrated architecture for massive parallel data treatment of analogue signals supplied by silicon detectors of very high spatial resolution

    International Nuclear Information System (INIS)

    Michel, J.

    1993-02-01

    This doctorate thesis studies an integrated architecture designed to a parallel massive treatment of analogue signals supplied by silicon detectors of very high spatial resolution. The first chapter is an introduction presenting the general outline and the triggering conditions of the spectrometer. Chapter two describes the operational structure of a microvertex detector made of Si micro-plates associated to the measuring chains. Information preconditioning is related to the pre-amplification stage, to the pile-up effects and to the reduction in the time characteristic due to the high counting rates. The chapter three describes the architecture of the analogue delay buffer, makes an analysis of the intrinsic noise and presents the operational testings and input/output control operations. The fourth chapter is devoted to the description of the analogue pulse shape processor and gives also the testings and the corresponding measurements on the circuit. Finally, the chapter five deals with the simplest modeling of the entire conditioning chain. Also, the testings and measuring procedures are here discussed. In conclusion the author presents some prospects for improving the signal-to-noise ratio by summation of the de-convoluted micro-paths. 78 refs., 78 figs., 1 annexe

  13. Evaluation of the effect of probe design parameters on ECT signal and development of eddy current probe for irradiated fuel rods

    International Nuclear Information System (INIS)

    Kwank, S. W.; Han, Y. K.; Woo, S. K.; Kim, T. W.; Park, J. Y.; Kim, B. J.; Park, J. Y.

    1999-01-01

    Eddy current test(ECT) is used to inspect not only the failed fuel rods but also peripheral rods during repairing of the failed fuel rods, to detect internal defects in irradiated fuel rods which could not be detected by ultrasonic test and visual test, and to obtain the data for determining the root cause of fuel rod failure. This study evaluates the effect of properties of test article, irradiated fuel rods, on the impedance diagram in order to reduce the difficulty of ECT signal analysis. The optimum eddy current probe design conditions for inspecting the irradiated fuel rods, is estimate by using experimental equations and the probe is manufactured based on the estimated conditions. The performance of developed eddy current probe and the optimum conditions is proved through characteristic comparison experiment with the probe purchased from the foreign vendor

  14. Crosswalking EAD: Collaboration in Archival Description

    Directory of Open Access Journals (Sweden)

    Amy McCrory

    2005-09-01

    Full Text Available Different library departments must work together, both formally and informally, in implementing encoded archival description and in repackaging descriptive information about archival collections to other formats, particularly machine-readable cataloging. The authors, one a technical services librarian and the other a special collections archivist, describe their experiences collaborating in these processes at The Ohio State University. Although other institutions may differ in their organizational structure, the authors hope to provide technical guidance, as well as a model of collaboration between archivists and technical services personnel. Careful dialogue and planning are essential to transcend the traditional divide between archival and library descriptive practices and systems.

  15. Design and characterization of a mixed-signal PCB for digital-to-analog conversion in a modular and scalable infrared scene projector

    Science.gov (United States)

    Benedict, Jacob

    Infra-red (IR) sensors have proven instrumental in a wide variety of fields from military to industrial applications. The proliferation of IR sensors has spawned an intense push for technologies that can test and calibrate the multitudes of IR sensors. One such technology, IR scene projection (IRSP), provides an inexpensive and safe method for the testing of IR sensor devices. Previous efforts have been conducted to develop IRSPs based on super-lattice light emitting diodes (SLEDS). A single-color 512x512 SLEDs system has been developed, produced, and tested as documented in Corey Lange's Master's thesis, and a GOMAC paper by Rodney McGee [1][2]. Current efforts are being undergone to develop a two-color 512x512 SLEDs system designated (TCSA). The following thesis discusses the design and implementation of a custom printed circuit board (PCB), known as the FMC 4DAC, that contains both analog and digital signals. Utilizing two 16-bit digital-to-analog converters (DAC) the purpose of the board is to provide four analog current output channels for driving the TCSA system to a maximum frame rate of 1 kHz. In addition, the board supports a scalable TCSA system architecture. Several copies of the board can be run in parallel to achieve a range of analog channels between 4 and 32.

  16. Design

    DEFF Research Database (Denmark)

    Volf, Mette

    Design - proces & metode iBog®  er enestående i sit fokus på afmystificering og operationalisering af designprocessens flygtige og komplekse karakter. Udgivelsen går bag om designerens daglige arbejde og giver et indblik i den kreative skabelsesproces, som designeren er en del af. Udover et bredt...... indblik i designerens arbejdsmetoder og designparametre giver Design - proces & metode en række eksempler fra anerkendte designvirksomheder, der gør det muligt at komme helt tæt på designerens virkelighed....

  17. Explaining reduction of pedestrian-motor vehicle crashes in Arkhangelsk, Russia, in 2005-2010.

    Science.gov (United States)

    Kudryavtsev, Alexander V; Nilssen, Odd; Lund, Johan; Grjibovski, Andrej M; Ytterstad, Børge

    2012-01-01

    To explain a reduction in pedestrian-motor vehicle crashes in Arkhangelsk, Russia, in 2005-2010. Retrospective ecological study. For 2005-2010, police data on pedestrian-motor vehicle crashes, traffic violations, and total motor vehicles (MVs) were combined with data on changes in national road traffic legislation and municipal road infrastructure. Negative binomial regression was used to investigate trends in monthly rates of pedestrian-motor vehicle crashes per total MVs and estimate changes in these rates per unit changes in the safety measures. During the 6 years, the police registered 2,565 pedestrian-motor vehicle crashes: 1,597 (62%) outside crosswalks, 766 (30%) on non-signalized crosswalks, and 202 (8%) on signalized crosswalks. Crash rates outside crosswalks and on signalized crosswalks decreased on average by 1.1% per month, whereas the crash rate on non-signalized crosswalks remained unchanged. Numbers of signalized and non-signalized crosswalks increased by 14 and 19%, respectively. Also, 10% of non-signalized crosswalks were combined with speed humps, and 4% with light-reflecting vertical signs. Pedestrian penalties for traffic violations increased 4-fold. Driver penalties for ignoring prohibiting signal and failure to give way to pedestrian on non-signalized crosswalk increased 7- and 8-fold, respectively. The rate of total registered drivers' traffic violations per total MVs decreased on average by 0.3% per month. All studied infrastructure and legislative measures had inverse associations with the rate of crashes outside crosswalks. The rate of crashes on signalized crosswalks showed inverse associations with related monetary penalties. The introduction of infrastructure and legislative measures is the most probable explanation of the reduction of pedestrian-motor vehicle crashes in Arkhangelsk. The overall reduction is due to decreases in rates of crashes outside crosswalks and on signalized crosswalks. No change was observed in the rate of

  18. Design

    Science.gov (United States)

    Buchanan, Richard; Cross, Nigel; Durling, David; Nelson, Harold; Owen, Charles; Valtonen, Anna; Boling, Elizabeth; Gibbons, Andrew; Visscher-Voerman, Irene

    2013-01-01

    Scholars representing the field of design were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Richard Buchanan, Nigel Cross, David Durling, Harold Nelson, Charles Owen, and Anna Valtonen. Scholars…

  19. SignalR blueprints

    CERN Document Server

    Ingebrigtsen, Einar

    2015-01-01

    This book is designed for software developers, primarily those with knowledge of C#, .NET, and JavaScript. Good knowledge and understanding of SignalR is assumed to allow efficient programming of core elements and applications in SignalR.

  20. Design

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Pettiway, Keon

    2017-01-01

    In this chapter, Ole B. Jensen takes a situational approach to mobilities to examine how ordinary life activities are structured by technology and design. Using “staging mobilities” as a theoretical approach, Jensen considers mobilities as overlapping, actions, interactions and decisions by desig...... by providing ideas about future research for investigating mobilities in situ as a kind of “staging,” which he notes is influenced by the “material turn” in social sciences....... with a brief description of how movement is studied within social sciences after the “mobilities turn” versus the idea of physical movement in transport geography and engineering. He then explains how “mobilities design” was derived from connections between traffic and architecture. Jensen concludes...

  1. ATP signals

    DEFF Research Database (Denmark)

    Novak, Ivana

    2016-01-01

    The Department of Biology at the University of Copenhagen explains the function of ATP signalling in the pancreas......The Department of Biology at the University of Copenhagen explains the function of ATP signalling in the pancreas...

  2. Signaling aggression.

    Science.gov (United States)

    van Staaden, Moira J; Searcy, William A; Hanlon, Roger T

    2011-01-01

    From psychological and sociological standpoints, aggression is regarded as intentional behavior aimed at inflicting pain and manifested by hostility and attacking behaviors. In contrast, biologists define aggression as behavior associated with attack or escalation toward attack, omitting any stipulation about intentions and goals. Certain animal signals are strongly associated with escalation toward attack and have the same function as physical attack in intimidating opponents and winning contests, and ethologists therefore consider them an integral part of aggressive behavior. Aggressive signals have been molded by evolution to make them ever more effective in mediating interactions between the contestants. Early theoretical analyses of aggressive signaling suggested that signals could never be honest about fighting ability or aggressive intentions because weak individuals would exaggerate such signals whenever they were effective in influencing the behavior of opponents. More recent game theory models, however, demonstrate that given the right costs and constraints, aggressive signals are both reliable about strength and intentions and effective in influencing contest outcomes. Here, we review the role of signaling in lieu of physical violence, considering threat displays from an ethological perspective as an adaptive outcome of evolutionary selection pressures. Fighting prowess is conveyed by performance signals whose production is constrained by physical ability and thus limited to just some individuals, whereas aggressive intent is encoded in strategic signals that all signalers are able to produce. We illustrate recent advances in the study of aggressive signaling with case studies of charismatic taxa that employ a range of sensory modalities, viz. visual and chemical signaling in cephalopod behavior, and indicators of aggressive intent in the territorial calls of songbirds. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Assessment of Nanobiotechnology-Targeted siRNA Designed to Inhibit NF-KappaB Classical and Alternative Signaling in Breast Tumor Macrophages

    Science.gov (United States)

    2014-07-01

    Intraductal Injection of LPS as a Mouse Model of Mastitis : Signaling Visualized via an NF-κB Reporter Transgenic. J Vis Exp. (67). pii: 4030. 2012. PMID...injection of LPS as a mouse model of mastitis : signaling visualized via an NF-κB reporter transgenic. Journal of Visualized Experiments 2012. 4(67...supplies, including media, fetal bovine serum, antibiotics, and nonessential amino acids, were obtained from Life Technologies (Carlsbad, CA). The

  4. Technical evaluation of the electrical, instrumentation, and control design aspects of the override of containment purge valve isolation and other engineered safety feature signals for the Fort Calhoun Nuclear Power Plant

    International Nuclear Information System (INIS)

    Hackett, D.B.

    1980-01-01

    This report documents the technical evaluation of the electrical, instrumentation, and control design aspects of the override of containment purge valve isolation and other engineered safety feature signals for the Fort Calhoun nuclear power plant. The review criteria are based on IEEE Std-279-1971 requirements for the safety signals to all purge and ventilation isolation valves. This report is supplied as part of the Selected Electrical, Instrumentation, and Control Systems Issues Program being conducted for the US Nuclear Regulatory Commission by Lawrence Livermore Laboratory

  5. Multiscale Signal Analysis and Modeling

    CERN Document Server

    Zayed, Ahmed

    2013-01-01

    Multiscale Signal Analysis and Modeling presents recent advances in multiscale analysis and modeling using wavelets and other systems. This book also presents applications in digital signal processing using sampling theory and techniques from various function spaces, filter design, feature extraction and classification, signal and image representation/transmission, coding, nonparametric statistical signal processing, and statistical learning theory. This book also: Discusses recently developed signal modeling techniques, such as the multiscale method for complex time series modeling, multiscale positive density estimations, Bayesian Shrinkage Strategies, and algorithms for data adaptive statistics Introduces new sampling algorithms for multidimensional signal processing Provides comprehensive coverage of wavelets with presentations on waveform design and modeling, wavelet analysis of ECG signals and wavelet filters Reviews features extraction and classification algorithms for multiscale signal and image proce...

  6. Foundations of signal processing

    CERN Document Server

    Vetterli, Martin; Goyal, Vivek K

    2014-01-01

    This comprehensive and engaging textbook introduces the basic principles and techniques of signal processing, from the fundamental ideas of signals and systems theory to real-world applications. Students are introduced to the powerful foundations of modern signal processing, including the basic geometry of Hilbert space, the mathematics of Fourier transforms, and essentials of sampling, interpolation, approximation and compression. The authors discuss real-world issues and hurdles to using these tools, and ways of adapting them to overcome problems of finiteness and localisation, the limitations of uncertainty and computational costs. Standard engineering notation is used throughout, making mathematical examples easy for students to follow, understand and apply. It includes over 150 homework problems and over 180 worked examples, specifically designed to test and expand students' understanding of the fundamentals of signal processing, and is accompanied by extensive online materials designed to aid learning, ...

  7. Molecular and Cellular Signaling

    CERN Document Server

    Beckerman, Martin

    2005-01-01

    A small number of signaling pathways, no more than a dozen or so, form a control layer that is responsible for all signaling in and between cells of the human body. The signaling proteins belonging to the control layer determine what kinds of cells are made during development and how they function during adult life. Malfunctions in the proteins belonging to the control layer are responsible for a host of human diseases ranging from neurological disorders to cancers. Most drugs target components in the control layer, and difficulties in drug design are intimately related to the architecture of the control layer. Molecular and Cellular Signaling provides an introduction to molecular and cellular signaling in biological systems with an emphasis on the underlying physical principles. The text is aimed at upper-level undergraduates, graduate students and individuals in medicine and pharmacology interested in broadening their understanding of how cells regulate and coordinate their core activities and how diseases ...

  8. Adaptive signal processor

    Energy Technology Data Exchange (ETDEWEB)

    Walz, H.V.

    1980-07-01

    An experimental, general purpose adaptive signal processor system has been developed, utilizing a quantized (clipped) version of the Widrow-Hoff least-mean-square adaptive algorithm developed by Moschner. The system accommodates 64 adaptive weight channels with 8-bit resolution for each weight. Internal weight update arithmetic is performed with 16-bit resolution, and the system error signal is measured with 12-bit resolution. An adapt cycle of adjusting all 64 weight channels is accomplished in 8 ..mu..sec. Hardware of the signal processor utilizes primarily Schottky-TTL type integrated circuits. A prototype system with 24 weight channels has been constructed and tested. This report presents details of the system design and describes basic experiments performed with the prototype signal processor. Finally some system configurations and applications for this adaptive signal processor are discussed.

  9. Adaptive signal processor

    International Nuclear Information System (INIS)

    Walz, H.V.

    1980-07-01

    An experimental, general purpose adaptive signal processor system has been developed, utilizing a quantized (clipped) version of the Widrow-Hoff least-mean-square adaptive algorithm developed by Moschner. The system accommodates 64 adaptive weight channels with 8-bit resolution for each weight. Internal weight update arithmetic is performed with 16-bit resolution, and the system error signal is measured with 12-bit resolution. An adapt cycle of adjusting all 64 weight channels is accomplished in 8 μsec. Hardware of the signal processor utilizes primarily Schottky-TTL type integrated circuits. A prototype system with 24 weight channels has been constructed and tested. This report presents details of the system design and describes basic experiments performed with the prototype signal processor. Finally some system configurations and applications for this adaptive signal processor are discussed

  10. Zinc Signals and Immunity.

    Science.gov (United States)

    Maywald, Martina; Wessels, Inga; Rink, Lothar

    2017-10-24

    Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency as well as zinc excess result in severe disturbances in immune cell numbers and activities, which can result in increased susceptibility to infections and development of especially inflammatory diseases. This review focuses on the role of zinc in regulating intracellular signaling pathways in innate as well as adaptive immune cells. Main underlying molecular mechanisms and targets affected by altered zinc homeostasis, including kinases, caspases, phosphatases, and phosphodiesterases, will be highlighted in this article. In addition, the interplay of zinc homeostasis and the redox metabolism in affecting intracellular signaling will be emphasized. Key signaling pathways will be described in detail for the different cell types of the immune system. In this, effects of fast zinc flux, taking place within a few seconds to minutes will be distinguish from slower types of zinc signals, also designated as "zinc waves", and late homeostatic zinc signals regarding prolonged changes in intracellular zinc.

  11. Biomedical signal and image processing

    CERN Document Server

    Najarian, Kayvan

    2012-01-01

    INTRODUCTION TO DIGITAL SIGNAL AND IMAGE PROCESSINGSignals and Biomedical Signal ProcessingIntroduction and OverviewWhat is a ""Signal""?Analog, Discrete, and Digital SignalsProcessing and Transformation of SignalsSignal Processing for Feature ExtractionSome Characteristics of Digital ImagesSummaryProblemsFourier TransformIntroduction and OverviewOne-Dimensional Continuous Fourier TransformSampling and NYQUIST RateOne-Dimensional Discrete Fourier TransformTwo-Dimensional Discrete Fourier TransformFilter DesignSummaryProblemsImage Filtering, Enhancement, and RestorationIntroduction and Overview

  12. Signal multiplexing scheme for LINAC

    International Nuclear Information System (INIS)

    Sujo, C.I.; Mohan, Shyam; Joshi, Gopal; Singh, S.K.; Karande, Jitendra

    2004-01-01

    For the proper operation of the LINAC some signals, RF (radio frequency) as well as LF (low frequency) have to be available at the Master Control Station (MCS). These signals are needed to control, calibrate and characterize the RF fields in the resonators. This can be achieved by proper multiplexing of various signals locally and then routing the selected signals to the MCS. A multiplexing scheme has been designed and implemented, which will allow the signals from the selected cavity to the MCS. High isolation between channels and low insertion loss for a given signal are important issues while selecting the multiplexing scheme. (author)

  13. Signal detection

    International Nuclear Information System (INIS)

    Tholomier, M.

    1985-01-01

    In a scanning electron microscope, whatever is the measured signal, the same set is found: incident beam, sample, signal detection, signal amplification. The resulting signal is used to control the spot luminosity with the observer cathodoscope. This is synchronized with the beam scanning on the sample; on the cathodoscope, the image in secondary electrons, backscattered electrons,... of the sample surface is reconstituted. The best compromise must be found between a register time low enough to remove eventual variations (under the incident beam) of the nature of the observed phenomenon, and a good spatial resolution of the image and a signal-to-noise ratio high enough. The noise is one of the basic limitations of the scanning electron microscope performance. The whose measurement line must be optimized to reduce it [fr

  14. Fundamentals of statistical signal processing

    CERN Document Server

    Kay, Steven M

    1993-01-01

    A unified presentation of parameter estimation for those involved in the design and implementation of statistical signal processing algorithms. Covers important approaches to obtaining an optimal estimator and analyzing its performance; and includes numerous examples as well as applications to real- world problems. MARKETS: For practicing engineers and scientists who design and analyze signal processing systems, i.e., to extract information from noisy signals — radar engineer, sonar engineer, geophysicist, oceanographer, biomedical engineer, communications engineer, economist, statistician, physicist, etc.

  15. Understanding signal integrity

    CERN Document Server

    Thierauf, Stephen C

    2010-01-01

    This unique book provides you with practical guidance on understanding and interpreting signal integrity (SI) performance to help you with your challenging circuit board design projects. You find high-level discussions of important SI concepts presented in a clear and easily accessible format, including question and answer sections and bulleted lists.This valuable resource features rules of thumb and simple equations to help you make estimates of critical signal integrity parameters without using circuit simulators of CAD (computer-aided design). The book is supported with over 120 illustratio

  16. VLSI design

    CERN Document Server

    Chandrasetty, Vikram Arkalgud

    2011-01-01

    This book provides insight into the practical design of VLSI circuits. It is aimed at novice VLSI designers and other enthusiasts who would like to understand VLSI design flows. Coverage includes key concepts in CMOS digital design, design of DSP and communication blocks on FPGAs, ASIC front end and physical design, and analog and mixed signal design. The approach is designed to focus on practical implementation of key elements of the VLSI design process, in order to make the topic accessible to novices. The design concepts are demonstrated using software from Mathworks, Xilinx, Mentor Graphic

  17. Machine intelligence and signal processing

    CERN Document Server

    Vatsa, Mayank; Majumdar, Angshul; Kumar, Ajay

    2016-01-01

    This book comprises chapters on key problems in machine learning and signal processing arenas. The contents of the book are a result of a 2014 Workshop on Machine Intelligence and Signal Processing held at the Indraprastha Institute of Information Technology. Traditionally, signal processing and machine learning were considered to be separate areas of research. However in recent times the two communities are getting closer. In a very abstract fashion, signal processing is the study of operator design. The contributions of signal processing had been to device operators for restoration, compression, etc. Applied Mathematicians were more interested in operator analysis. Nowadays signal processing research is gravitating towards operator learning – instead of designing operators based on heuristics (for example wavelets), the trend is to learn these operators (for example dictionary learning). And thus, the gap between signal processing and machine learning is fast converging. The 2014 Workshop on Machine Intel...

  18. Power Efficient Design of DisplayPort (7.0) Using Low-voltage differential signaling IO Standard Via UltraScale Field Programming Gate Arrays

    DEFF Research Database (Denmark)

    Das, Bhagwan; Abdullah, M.F.L.; Hussain, Dil muhammed Akbar

    2017-01-01

    Port (7.0) need be reduced. In this paper, a power efficient design for DisplayPort (7.0) is proposed using LVDS IO Standard. The proposed design is tested for different frequencies; 500 MHz, 700 MHz, 1.0 GHz, and 1.6 GHz. The design is implemented using vhdl in UltraScale FPGA. It is determined...... the designed vhdl based design of DisplayPort (7.0) can reduced 92% using LVDS IO Standard for all frequencies; 500 MHz, 700 MHz, 1.0 GHz, and 1.6 GHz, compared to vhdl based design of DisplayPort (7.0) without using IO Standard. The proposed design of vhdl based design of DisplayPort (7.0) using LVDS IO...... Standard offers no power consumption for DisplayPort (7.0) in standby mode. The vhdl based design of DisplayPort (7.0) using LVDS IO Standard will be helpful to process the high resolution video at low power consumption....

  19. Small-Signal Modeling of the PVR-Based AD Scheme and Controller Design for Three-Phase Standalone DG System

    DEFF Research Database (Denmark)

    Shen, Pan; Han, Yang; Lu, Chang

    2016-01-01

    This paper presents the small-signal state-space modeling and a new multifunctional multi-loop control strategy for three-phase inverter-based islanded DG systems under unbalanced and/or nonlinear load conditions. The proposed control methodology utilizes the parallel virtual resistance (PVR...... controllers are based on an enhanced proportional resonant (PR) structure to achieve zero steady-state error, and multi-resonant harmonic compensator (MRHC) plus PR controller to prevent low-order load current harmonics to distort the output voltage. The proposed small-signal model of the islanded DG system...... with multi-loop control strategy in the stationary reference frame is presented. Moreover, an enhanced delay compensation (EDC) scheme based on two integrators of the discrete PR controller is presented to improve stability margins with a higher accuracy compared with the existing methods. Then, a detailed...

  20. Signal integrity characterization techniques

    CERN Document Server

    Bogatin, Eric

    2009-01-01

    "Signal Integrity Characterization Techniques" addresses the gap between traditional digital and microwave curricula all while focusing on a practical and intuitive understanding of signal integrity effects within the data transmission channel. High-speed interconnects such as connectors, PCBs, cables, IC packages, and backplanes are critical elements of differential channels that must be designed using today's most powerful analysis and characterization tools.Both measurements and simulation must be done on the device under test, and both activities must yield data that correlates with each other. Most of this book focuses on real-world applications of signal integrity measurements - from backplane for design challenges to error correction techniques to jitter measurement technologies. The authors' approach wisely addresses some of these new high-speed technologies, and it also provides valuable insight into its future direction and will teach the reader valuable lessons on the industry.

  1. Design Methodology of an Equalizer for Unipolar Non Return to Zero Binary Signals in the Presence of Additive White Gaussian Noise Using a Time Delay Neural Network on a Field Programmable Gate Array

    Science.gov (United States)

    Pérez Suárez, Santiago T.; Travieso González, Carlos M.; Alonso Hernández, Jesús B.

    2013-01-01

    This article presents a design methodology for designing an artificial neural network as an equalizer for a binary signal. Firstly, the system is modelled in floating point format using Matlab. Afterward, the design is described for a Field Programmable Gate Array (FPGA) using fixed point format. The FPGA design is based on the System Generator from Xilinx, which is a design tool over Simulink of Matlab. System Generator allows one to design in a fast and flexible way. It uses low level details of the circuits and the functionality of the system can be fully tested. System Generator can be used to check the architecture and to analyse the effect of the number of bits on the system performance. Finally the System Generator design is compiled for the Xilinx Integrated System Environment (ISE) and the system is described using a hardware description language. In ISE the circuits are managed with high level details and physical performances are obtained. In the Conclusions section, some modifications are proposed to improve the methodology and to ensure portability across FPGA manufacturers.

  2. Design Methodology of an Equalizer for Unipolar Non Return to Zero Binary Signals in the Presence of Additive White Gaussian Noise Using a Time Delay Neural Network on a Field Programmable Gate Array

    Directory of Open Access Journals (Sweden)

    Santiago T. Pérez Suárez

    2013-12-01

    Full Text Available This article presents a design methodology for designing an artificial neural network as an equalizer for a binary signal. Firstly, the system is modelled in floating point format using Matlab. Afterward, the design is described for a Field Programmable Gate Array (FPGA using fixed point format. The FPGA design is based on the System Generator from Xilinx, which is a design tool over Simulink of Matlab. System Generator allows one to design in a fast and flexible way. It uses low level details of the circuits and the functionality of the system can be fully tested. System Generator can be used to check the architecture and to analyse the effect of the number of bits on the system performance. Finally the System Generator design is compiled for the Xilinx Integrated System Environment (ISE and the system is described using a hardware description language. In ISE the circuits are managed with high level details and physical performances are obtained. In the Conclusions section, some modifications are proposed to improve the methodology and to ensure portability across FPGA manufacturers.

  3. Digital signal processing the Tevatron BPM signals

    International Nuclear Information System (INIS)

    Cancelo, G.; James, E.; Wolbers, S.

    2005-01-01

    The Beam Position Monitor (TeV BPM) readout system at Fermilab's Tevatron has been updated and is currently being commissioned. The new BPMs use new analog and digital hardware to achieve better beam position measurement resolution. The new system reads signals from both ends of the existing directional stripline pickups to provide simultaneous proton and antiproton measurements. The signals provided by the two ends of the BPM pickups are processed by analog band-pass filters and sampled by 14-bit ADCs at 74.3MHz. A crucial part of this work has been the design of digital filters that process the signal. This paper describes the digital processing and estimation techniques used to optimize the beam position measurement. The BPM electronics must operate in narrow-band and wide-band modes to enable measurements of closed-orbit and turn-by-turn positions. The filtering and timing conditions of the signals are tuned accordingly for the operational modes. The analysis and the optimized result for each mode are presented

  4. VLSI signal processing technology

    CERN Document Server

    Swartzlander, Earl

    1994-01-01

    This book is the first in a set of forthcoming books focussed on state-of-the-art development in the VLSI Signal Processing area. It is a response to the tremendous research activities taking place in that field. These activities have been driven by two factors: the dramatic increase in demand for high speed signal processing, especially in consumer elec­ tronics, and the evolving microelectronic technologies. The available technology has always been one of the main factors in determining al­ gorithms, architectures, and design strategies to be followed. With every new technology, signal processing systems go through many changes in concepts, design methods, and implementation. The goal of this book is to introduce the reader to the main features of VLSI Signal Processing and the ongoing developments in this area. The focus of this book is on: • Current developments in Digital Signal Processing (DSP) pro­ cessors and architectures - several examples and case studies of existing DSP chips are discussed in...

  5. Signal processing in microdosimetry

    International Nuclear Information System (INIS)

    Arbel, A.

    1984-01-01

    Signals occurring in microdosimetric measurements cover a dynamic range of 100 dB at a counting rate which normally stays below 10 4 but could increase significantly in case of an accident. The need for high resolution at low energies, non-linear signal processing to accommodate the specified dynamic range, easy calibration and thermal stability are conflicting requirements which pose formidable design problems. These problems are reviewed, and a practical approach to their solution is given employing a single processing channel. (author)

  6. Electronic signal conditioning

    CERN Document Server

    NEWBY, BRUCE

    1994-01-01

    At technician level, brief references to signal conditioning crop up in a fragmented way in various textbooks, but there has been no single textbook, until now!More advanced texts do exist but they are more mathematical and presuppose a higher level of understanding of electronics and statistics. Electronic Signal Conditioning is designed for HNC/D students and City & Guilds Electronics Servicing 2240 Parts 2 & 3. It will also be useful for BTEC National, Advanced GNVQ, A-level electronics and introductory courses at degree level.

  7. Signals and systems with MATLAB

    CERN Document Server

    Yang, Won Young; Song, Ik H; Cho, Yong S

    2009-01-01

    Covers some of the theoretical foundations and mathematical derivations that can be used in higher-level related subjects such as signal processing, communication, and control, minimizing the mathematical difficulty and computational burden. This book illustrates the usage of MATLAB and Simulink for signal and system analysis and design.

  8. Using LabVIEW for the design and control of digital signal processing systems. Simulation of the ultra slow extraction at COSY

    International Nuclear Information System (INIS)

    Heinrichs, G.; Rongen, H.; Jamal, R.

    1994-01-01

    For the ultraslow extraction system of the COler SYnchrotron COSY a direct digital synthesis system is being developed. LabVIEW from National Instruments has been chosen as a tool for the simulation of the digital signal processing algorithms as well as the generation of test sequences. In order to generate adjustable band-limited noise centered at a carrier frequency, alternative algorithms have been studied. LabVIEW permits the interactive variation of relevant system parameters by means of a graphical language in order to study the quality of the frequency band limitation as a function of noise parameters, digital accuracy and frequency range and to generate test sequences by means of a real-time function generator. Advantages and limitations of LabVIEW for such applications are discussed. ((orig.))

  9. Nuclear Receptor Signaling Atlas (NURSA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Nuclear Receptor Signaling Atlas (NURSA) is designed to foster the development of a comprehensive understanding of the structure, function, and role in disease...

  10. C-HEAP : a heterogeneous multi-processor architecture template and scalable and flexible protocol for the design of embedded signal processing systems

    NARCIS (Netherlands)

    Nieuwland, A.K.; Kang, J.; Gangwal, O.P.; Sethuraman, R.; Busá, N.G.; Goossens, K.G.W.; Peset Llopis, R.; Lippens, P.E.R.

    2002-01-01

    The key issue in the design of Systems-on-a-Chip (SoC) is to trade-off efficiency against flexibility, and time to market versus cost. Current deep submicron processing technologies enable integration of multiple software programmable processors (e.g., CPUs, DSPs) and dedicated hardware components

  11. Handbook of signal processing systems

    CERN Document Server

    Deprettere, Ed; Leupers, Rainer; Takala, Jarmo

    2013-01-01

    Handbook of Signal Processing Systems is organized in three parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications; the third part focuses on compilers and simulation tools, describes models of computation and their associated design tools and methodologies. This handbook is an essential tool for professionals in many fields and researchers of all levels.

  12. Design and implementation of a radiation hardened silicon on sapphire (SOS) embedded signal conditioning unit controller (SCUC) for the RAPID instrument on the Cluster satellites

    International Nuclear Information System (INIS)

    Ersland, L.

    1992-07-01

    The Cluster mission consistens of four spacecrafts equipped with instruments capable of making comprehensive measurements of plasma particles and electromagnetic fields. The RAPID (Research with Adaptive Particle Imaging Detectors) spectrometer is one of many instruments on board the Cluster satellites. It is designed for fast analysis of energetic electrons and ions with a complete coverage of the unit sphere in phase space. This thesis describes the development and testing of an embedded controller for the Spectroscopic Camera for Electrons, Neutral and Ion Compositions (SCENIC), which is a part of the RAPID instrument. The design is implemented in two different CMOS circuit technologies, namely Actel's Field Programmable Gate Arrays and GEC Plessey's CMOS Silicon On Sapphire (SOS) gate array. The prototypes of the SOS gate array have been verified and characterized. This includes measurements of DC and AC parameters under different conditions, including total dose of gamma irradiation. 42 refs., 92 figs., 44 tabs

  13. Signal generation in gas detectors

    International Nuclear Information System (INIS)

    Stillman, A.

    1993-01-01

    This tutorial describes the generation of electrical signals in gas detectors. Ionization of the gas by the passage of charged particles generates these signals. Starting with the Bethe-Bloch equation, the treatment is a general introduction to the production of ion-pairs in gas devices. I continue with the characterization of the ionization as an electrical signal, and calculate the signal current in a simple example. Another example demonstrates the effect of space charge on the design of a detector. The AGS Booster ionization profile monitor is a model for this calculation

  14. Experimental and computational analysis of a large protein network that controls fat storage reveals the design principles of a signaling network.

    Directory of Open Access Journals (Sweden)

    Bader Al-Anzi

    2015-05-01

    Full Text Available An approach combining genetic, proteomic, computational, and physiological analysis was used to define a protein network that regulates fat storage in budding yeast (Saccharomyces cerevisiae. A computational analysis of this network shows that it is not scale-free, and is best approximated by the Watts-Strogatz model, which generates "small-world" networks with high clustering and short path lengths. The network is also modular, containing energy level sensing proteins that connect to four output processes: autophagy, fatty acid synthesis, mRNA processing, and MAP kinase signaling. The importance of each protein to network function is dependent on its Katz centrality score, which is related both to the protein's position within a module and to the module's relationship to the network as a whole. The network is also divisible into subnetworks that span modular boundaries and regulate different aspects of fat metabolism. We used a combination of genetics and pharmacology to simultaneously block output from multiple network nodes. The phenotypic results of this blockage define patterns of communication among distant network nodes, and these patterns are consistent with the Watts-Strogatz model.

  15. Experimental and computational analysis of a large protein network that controls fat storage reveals the design principles of a signaling network.

    Science.gov (United States)

    Al-Anzi, Bader; Arpp, Patrick; Gerges, Sherif; Ormerod, Christopher; Olsman, Noah; Zinn, Kai

    2015-05-01

    An approach combining genetic, proteomic, computational, and physiological analysis was used to define a protein network that regulates fat storage in budding yeast (Saccharomyces cerevisiae). A computational analysis of this network shows that it is not scale-free, and is best approximated by the Watts-Strogatz model, which generates "small-world" networks with high clustering and short path lengths. The network is also modular, containing energy level sensing proteins that connect to four output processes: autophagy, fatty acid synthesis, mRNA processing, and MAP kinase signaling. The importance of each protein to network function is dependent on its Katz centrality score, which is related both to the protein's position within a module and to the module's relationship to the network as a whole. The network is also divisible into subnetworks that span modular boundaries and regulate different aspects of fat metabolism. We used a combination of genetics and pharmacology to simultaneously block output from multiple network nodes. The phenotypic results of this blockage define patterns of communication among distant network nodes, and these patterns are consistent with the Watts-Strogatz model.

  16. Integrin Signalling

    OpenAIRE

    Schelfaut, Roselien

    2005-01-01

    Integrins are receptors presented on most cells. By binding ligand they can generate signalling pathways inside the cell. Those pathways are a linkage to proteins in the cytosol. It is known that tumor cells can survive and proliferate in the absence of a solid support while normal cells need to be bound to ligand. To understand why tumour cells act that way, we first have to know how ligand-binding to integrins affect the cell. This research field includes studies on activation of proteins b...

  17. Experiment and practice on signal processing

    International Nuclear Information System (INIS)

    2002-11-01

    The contents of this book contains basic practice of CEM Tool, discrete time signal and experiment and practice of system, experiment and practice of discrete time signal sampling, practice of frequency analysis, experiment of digital filter design, application of digital signal processing, project related voice, basic principle of signal processing, the technique of basic image signal processing, biology astronomy and Robot soccer with apply of image signal processing technique, control video signal and project related image. It also has an introduction of CEM Linker I. O in the end.

  18. Experiment and practice on signal processing

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-11-15

    The contents of this book contains basic practice of CEM Tool, discrete time signal and experiment and practice of system, experiment and practice of discrete time signal sampling, practice of frequency analysis, experiment of digital filter design, application of digital signal processing, project related voice, basic principle of signal processing, the technique of basic image signal processing, biology astronomy and Robot soccer with apply of image signal processing technique, control video signal and project related image. It also has an introduction of CEM Linker I. O in the end.

  19. Design Optimization and Fabrication of High-Sensitivity SOI Pressure Sensors with High Signal-to-Noise Ratios Based on Silicon Nanowire Piezoresistors

    Directory of Open Access Journals (Sweden)

    Jiahong Zhang

    2016-10-01

    Full Text Available In order to meet the requirement of high sensitivity and signal-to-noise ratios (SNR, this study develops and optimizes a piezoresistive pressure sensor by using double silicon nanowire (SiNW as the piezoresistive sensing element. First of all, ANSYS finite element method and voltage noise models are adopted to optimize the sensor size and the sensor output (such as sensitivity, voltage noise and SNR. As a result, the sensor of the released double SiNW has 1.2 times more sensitivity than that of single SiNW sensor, which is consistent with the experimental result. Our result also displays that both the sensitivity and SNR are closely related to the geometry parameters of SiNW and its doping concentration. To achieve high performance, a p-type implantation of 5 × 1018 cm−3 and geometry of 10 µm long SiNW piezoresistor of 1400 nm × 100 nm cross area and 6 µm thick diaphragm of 200 µm × 200 µm are required. Then, the proposed SiNW pressure sensor is fabricated by using the standard complementary metal-oxide-semiconductor (CMOS lithography process as well as wet-etch release process. This SiNW pressure sensor produces a change in the voltage output when the external pressure is applied. The involved experimental results show that the pressure sensor has a high sensitivity of 495 mV/V·MPa in the range of 0–100 kPa. Nevertheless, the performance of the pressure sensor is influenced by the temperature drift. Finally, for the sake of obtaining accurate and complete information over wide temperature and pressure ranges, the data fusion technique is proposed based on the back-propagation (BP neural network, which is improved by the particle swarm optimization (PSO algorithm. The particle swarm optimization–back-propagation (PSO–BP model is implemented in hardware using a 32-bit STMicroelectronics (STM32 microcontroller. The results of calibration and test experiments clearly prove that the PSO–BP neural network can be effectively applied

  20. Design and synthesis of BODIPY-clickate based Hg(2+) sensors: the effect of triazole binding mode with Hg(2+) on signal transduction.

    Science.gov (United States)

    Vedamalai, Mani; Kedaria, Dhaval; Vasita, Rajesh; Mori, Shigeki; Gupta, Iti

    2016-02-14

    BODIPY-clickates, F1 and F2, for the detection of Hg(2+) have been designed, synthesized and characterized. Both F1 and F2 showed hyperchromic shifts in the UV-visible spectra in response to increasing Hg(2+) concentrations. Hg(2+) ion binding caused perturbation of the emission quenching process and chelation induced enhanced bathochromic emission of F1 and F2 to 620 nm and 660 nm, respectively. Job's plot clearly indicated that the binding ratio of F1 and F2 with Hg(2+) was 1 : 1. The NMR titration of BODIPY-clickates with Hg(2+) confirmed that aromatic amines and triazoles were involved in the binding event. Furthermore, HRMS data of F1-Hg(2+) and F2-Hg(2+) supported the formation of mercury complexes of BODIPY-clickates. The dissociation constant for the interaction between fluorescent probes F1 and F2 with Hg(2+) was found to be 24.4 ± 5.1 μM and 22.0 ± 3.9 μM, respectively. The Hg(2+) ion induced fluorescence enhancement was almost stable in a pH range of 5 to 8. Having less toxicity to live cells, both the probes were successfully used to map the Hg(2+) ions in live A549 cells.

  1. 一种接口兼容的非接触式呼吸信号检测系统的设计与研究%Design and Research of an Interface Compatible Non-contacting Respiratory Signal Detection System

    Institute of Scientific and Technical Information of China (English)

    宋奎; 齐家俊; 林涛; 张逸

    2011-01-01

    Respiration-induced displacements of organs greatly affect the safety and efficiency of high intensity focused ultrasound (HIFU) tumor therapy system. The key to solve this problem is accurate, real-time detection of respiratory signals. The present study gives a new design of an interface compatible non-contacting respiratory signal detection system using the method of irradiating the laser beam onto certain region of the surface of human body that is intensely influenced by the breathing movements (mostly the breast or the dorsum) at a certain angle, and meanwhile using a camera to aquire information from the location of the laser projection. Then we can draw a curve of the location of laser projection versus time base, that is the respiration curve. This respiratory signal detection method is non-contacting, interface compatible and easy to be integrated into the treatment system.%呼吸运动引发的体内脏器移位极大影响高强度聚焦超声(HIFU)肿瘤治疗系统的安全性和治疗效率.解决这一问题的关键是实时、准确的呼吸信号检测.以一定角度,用激光束在人体表受呼吸运动影响较大的部位(一般是胸部或背部)投射激光点,用摄像机采集激光点位置信息.描绘激光点位置与采集时刻的关系曲线,即呼吸曲线.该呼吸信号检测方法为非接触式,同时具有接口兼容性好的优点,便于集成到治疗系统中.

  2. Structure-Based Design and Synthesis of a Small Molecule that Exhibits Anti-inflammatory Activity by Inhibition of MyD88-mediated Signaling to Bacterial Toxin Exposure.

    Science.gov (United States)

    Alam, Shahabuddin; Javor, Sacha; Degardin, Melissa; Ajami, Dariush; Rebek, Mitra; Kissner, Teri L; Waag, David M; Rebek, Julius; Saikh, Kamal U

    2015-08-01

    Both Gram-positive and Gram-negative pathogens or pathogen-derived components, such as staphylococcal enterotoxins (SEs) and endotoxin (LPS) exposure, activate MyD88-mediated pro-inflammatory cellular immunity for host defense. However, dysregulated MyD88-mediated signaling triggers exaggerated immune response that often leads to toxic shock and death. Previously, we reported a small molecule compound 1 mimicking BB-loop structure of MyD88 was capable of inhibiting pro-inflammatory response to SEB exposure in mice. In this study, we designed a dimeric structure compound 4210 covalently linked with compound 1 by a non-polar cyclohexane linker which strongly inhibited the production of pro-inflammatory cytokines in human primary cells to SEB (IC50 1-50 μm) or LPS extracted from Francisella tularensis, Escherichia coli, or Burkholderia mallei (IC50 10-200 μm). Consistent with cytokine inhibition, in a ligand-induced cell-based reporter assay, compound 4210 inhibited Burkholderia mallei or LPS-induced MyD88-mediated NF-kB-dependent expression of reporter activity (IC50 10-30 μm). Furthermore, results from a newly expressed MyD88 revealed that 4210 inhibited MyD88 dimer formation which is critical for pro-inflammatory signaling. Importantly, a single administration of compound 4210 in mice showed complete protection from lethal toxin challenge. Collectively, these results demonstrated that compound 4210 inhibits toxin-induced inflated pro-inflammatory immune signaling, thus displays a potential bacterial toxin therapeutic. © 2014 John Wiley & Sons A/S.

  3. Radar signal analysis and processing using Matlab

    CERN Document Server

    Mahafza, Bassem R

    2008-01-01

    Offering radar-related software for the analysis and design of radar waveform and signal processing, this book provides comprehensive coverage of radar signals and signal processing techniques and algorithms. It contains numerous graphical plots, common radar-related functions, table format outputs, and end-of-chapter problems. The complete set of MATLAB[registered] functions and routines are available for download online.

  4. Digital Signal Processing applied to Physical Signals

    CERN Document Server

    Alberto, Diego; Musa, L

    2011-01-01

    It is well known that many of the scientific and technological discoveries of the XXI century will depend on the capability of processing and understanding a huge quantity of data. With the advent of the digital era, a fully digital and automated treatment can be designed and performed. From data mining to data compression, from signal elaboration to noise reduction, a processing is essential to manage and enhance features of interest after every data acquisition (DAQ) session. In the near future, science will go towards interdisciplinary research. In this work there will be given an example of the application of signal processing to different fields of Physics from nuclear particle detectors to biomedical examinations. In Chapter 1 a brief description of the collaborations that allowed this thesis is given, together with a list of the publications co-produced by the author in these three years. The most important notations, definitions and acronyms used in the work are also provided. In Chapter 2, the last r...

  5. Aberrant Signaling Pathways in Glioma

    International Nuclear Information System (INIS)

    Nakada, Mitsutoshi; Kita, Daisuke; Watanabe, Takuya; Hayashi, Yutaka; Teng, Lei; Pyko, Ilya V.; Hamada, Jun-Ichiro

    2011-01-01

    Glioblastoma multiforme (GBM), a WHO grade IV malignant glioma, is the most common and lethal primary brain tumor in adults; few treatments are available. Median survival rates range from 12–15 months. The biological characteristics of this tumor are exemplified by prominent proliferation, active invasiveness, and rich angiogenesis. This is mainly due to highly deregulated signaling pathways in the tumor. Studies of these signaling pathways have greatly increased our understanding of the biology and clinical behavior of GBM. An integrated view of signal transduction will provide a more useful approach in designing novel therapies for this devastating disease. In this review, we summarize the current understanding of GBM signaling pathways with a focus on potential molecular targets for anti-signaling molecular therapies

  6. Signaling equilibria in sensorimotor interactions.

    Science.gov (United States)

    Leibfried, Felix; Grau-Moya, Jordi; Braun, Daniel A

    2015-08-01

    Although complex forms of communication like human language are often assumed to have evolved out of more simple forms of sensorimotor signaling, less attention has been devoted to investigate the latter. Here, we study communicative sensorimotor behavior of humans in a two-person joint motor task where each player controls one dimension of a planar motion. We designed this joint task as a game where one player (the sender) possesses private information about a hidden target the other player (the receiver) wants to know about, and where the sender's actions are costly signals that influence the receiver's control strategy. We developed a game-theoretic model within the framework of signaling games to investigate whether subjects' behavior could be adequately described by the corresponding equilibrium solutions. The model predicts both separating and pooling equilibria, in which signaling does and does not occur respectively. We observed both kinds of equilibria in subjects and found that, in line with model predictions, the propensity of signaling decreased with increasing signaling costs and decreasing uncertainty on the part of the receiver. Our study demonstrates that signaling games, which have previously been applied to economic decision-making and animal communication, provide a framework for human signaling behavior arising during sensorimotor interactions in continuous and dynamic environments. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Intracellular signal modulation by nanomaterials.

    Science.gov (United States)

    Hussain, Salik; Garantziotis, Stavros; Rodrigues-Lima, Fernando; Dupret, Jean-Marie; Baeza-Squiban, Armelle; Boland, Sonja

    2014-01-01

    A thorough understanding of the interactions of nanomaterials with biological systems and the resulting activation of signal transduction pathways is essential for the development of safe and consumer friendly nanotechnology. Here we present an overview of signaling pathways induced by nanomaterial exposures and describe the possible correlation of their physicochemical characteristics with biological outcomes. In addition to the hierarchical oxidative stress model and a review of the intrinsic and cell-mediated mechanisms of reactive oxygen species (ROS) generating capacities of nanomaterials, we also discuss other oxidative stress dependent and independent cellular signaling pathways. Induction of the inflammasome, calcium signaling, and endoplasmic reticulum stress are reviewed. Furthermore, the uptake mechanisms can be of crucial importance for the cytotoxicity of nanomaterials and membrane-dependent signaling pathways have also been shown to be responsible for cellular effects of nanomaterials. Epigenetic regulation by nanomaterials, effects of nanoparticle-protein interactions on cell signaling pathways, and the induction of various cell death modalities by nanomaterials are described. We describe the common trigger mechanisms shared by various nanomaterials to induce cell death pathways and describe the interplay of different modalities in orchestrating the final outcome after nanomaterial exposures. A better understanding of signal modulations induced by nanomaterials is not only essential for the synthesis and design of safer nanomaterials but will also help to discover potential nanomedical applications of these materials. Several biomedical applications based on the different signaling pathways induced by nanomaterials are already proposed and will certainly gain a great deal of attraction in the near future.

  8. Signal conflict in spider webs driven by predators and prey

    OpenAIRE

    Blackledge, T. A.

    1998-01-01

    Variation in the sensory physiologies of organisms can bias the receptions of signals, driving the direction of signal evolution. Sensory drive in the evolution of signals may be particularly important for organisms that confront trade-offs in signal design between the need for conspicuousness to allow effective transfer of information and the need for crypsis of the signal to unintended receivers. Several genera of orb-weaving spiders include conspicuous silk designs, stabilimenta, in the ce...

  9. Design junctions

    DEFF Research Database (Denmark)

    Jørgensen, Ulrik

    2012-01-01

    . This case study illustrates how dominant regimes of practice, established through the conception of pathogen bacteria and antibacterial treatments and disinfection, are now creating signals that call into question fundamental design of hygiene practices. By examining the epistemic assumptions of scientific...

  10. Digital storage of repeated signals

    International Nuclear Information System (INIS)

    Prozorov, S.P.

    1984-01-01

    An independent digital storage system designed for repeated signal discrimination from background noises is described. The signal averaging is performed off-line in the real time mode by means of multiple selection of the investigated signal and integration in each point. Digital values are added in a simple summator and the result is recorded the storage device with the volume of 1024X20 bit from where it can be output on an oscillograph, a plotter or transmitted to a compUter for subsequent processing. The described storage is reliable and simple device on one base of which the systems for the nuclear magnetic resonapce signal acquisition in different experiments are developed

  11. Basic digital signal processing

    CERN Document Server

    Lockhart, Gordon B

    1985-01-01

    Basic Digital Signal Processing describes the principles of digital signal processing and experiments with BASIC programs involving the fast Fourier theorem (FFT). The book reviews the fundamentals of the BASIC program, continuous and discrete time signals including analog signals, Fourier analysis, discrete Fourier transform, signal energy, power. The text also explains digital signal processing involving digital filters, linear time-variant systems, discrete time unit impulse, discrete-time convolution, and the alternative structure for second order infinite impulse response (IIR) sections.

  12. Modified BTC Algorithm for Audio Signal Coding

    Directory of Open Access Journals (Sweden)

    TOMIC, S.

    2016-11-01

    Full Text Available This paper describes modification of a well-known image coding algorithm, named Block Truncation Coding (BTC and its application in audio signal coding. BTC algorithm was originally designed for black and white image coding. Since black and white images and audio signals have different statistical characteristics, the application of this image coding algorithm to audio signal presents a novelty and a challenge. Several implementation modifications are described in this paper, while the original idea of the algorithm is preserved. The main modifications are performed in the area of signal quantization, by designing more adequate quantizers for audio signal processing. The result is a novel audio coding algorithm, whose performance is presented and analyzed in this research. The performance analysis indicates that this novel algorithm can be successfully applied in audio signal coding.

  13. Retroactive signaling in short signaling pathways.

    Directory of Open Access Journals (Sweden)

    Jacques-Alexandre Sepulchre

    Full Text Available In biochemical signaling pathways without explicit feedback connections, the core signal transduction is usually described as a one-way communication, going from upstream to downstream in a feedforward chain or network of covalent modification cycles. In this paper we explore the possibility of a new type of signaling called retroactive signaling, offered by the recently demonstrated property of retroactivity in signaling cascades. The possibility of retroactive signaling is analysed in the simplest case of the stationary states of a bicyclic cascade of signaling cycles. In this case, we work out the conditions for which variables of the upstream cycle are affected by a change of the total amount of protein in the downstream cycle, or by a variation of the phosphatase deactivating the same protein. Particularly, we predict the characteristic ranges of the downstream protein, or of the downstream phosphatase, for which a retroactive effect can be observed on the upstream cycle variables. Next, we extend the possibility of retroactive signaling in short but nonlinear signaling pathways involving a few covalent modification cycles.

  14. Pseudo random signal processing theory and application

    CERN Document Server

    Zepernick, Hans-Jurgen

    2013-01-01

    In recent years, pseudo random signal processing has proven to be a critical enabler of modern communication, information, security and measurement systems. The signal's pseudo random, noise-like properties make it vitally important as a tool for protecting against interference, alleviating multipath propagation and allowing the potential of sharing bandwidth with other users. Taking a practical approach to the topic, this text provides a comprehensive and systematic guide to understanding and using pseudo random signals. Covering theoretical principles, design methodologies and applications

  15. Prototype real-time baseband signal combiner. [deep space network

    Science.gov (United States)

    Howard, L. D.

    1980-01-01

    The design and performance of a prototype real-time baseband signal combiner, used to enhance the received Voyager 2 spacecraft signals during the Jupiter flyby, is described. Hardware delay paths, operating programs, and firmware are discussed.

  16. Signal Analysis for Radiation Event Identification

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Wallace

    2004-12-30

    The method of digitizing the scintillation output signals from a lithiated sol-gel based glass is described. The design considerations for using the lithiated scintillator for the detection of Special Nuclear Material (SNM) is presented.

  17. Neural networks in signal processing

    International Nuclear Information System (INIS)

    Govil, R.

    2000-01-01

    Nuclear Engineering has matured during the last decade. In research and design, control, supervision, maintenance and production, mathematical models and theories are used extensively. In all such applications signal processing is embedded in the process. Artificial Neural Networks (ANN), because of their nonlinear, adaptive nature are well suited to such applications where the classical assumptions of linearity and second order Gaussian noise statistics cannot be made. ANN's can be treated as nonparametric techniques, which can model an underlying process from example data. They can also adopt their model parameters to statistical change with time. Algorithms in the framework of Neural Networks in Signal processing have found new applications potentials in the field of Nuclear Engineering. This paper reviews the fundamentals of Neural Networks in signal processing and their applications in tasks such as recognition/identification and control. The topics covered include dynamic modeling, model based ANN's, statistical learning, eigen structure based processing and generalization structures. (orig.)

  18. Radar signal processing and its applications

    CERN Document Server

    Hummel, Robert; Stoica, Petre; Zelnio, Edmund

    2003-01-01

    Radar Signal Processing and Its Applications brings together in one place important contributions and up-to-date research results in this fast-moving area. In twelve selected chapters, it describes the latest advances in architectures, design methods, and applications of radar signal processing. The contributors to this work were selected from the leading researchers and practitioners in the field. This work, originally published as Volume 14, Numbers 1-3 of the journal, Multidimensional Systems and Signal Processing, will be valuable to anyone working or researching in the field of radar signal processing. It serves as an excellent reference, providing insight into some of the most challenging issues being examined today.

  19. Plant monitoring and signal validation at HFIR

    International Nuclear Information System (INIS)

    Mullens, J.A.

    1991-01-01

    This paper describes a monitoring system for the Oak Ridge National Laboratory's (ORNL'S) High Flux Isotope Reactor (HFIR). HFIR is an 85 MW pressurized water reactor designed to produce isotopes and intense neutron beams. The monitoring system is described with respect to plant signals and computer system; monitoring overview; data acquisition, logging and network distribution; signal validation; status displays; reactor condition monitoring; reactor operator aids. Future work will include the addition of more plant signals, more signal validation and diagnostic capabilities, improved status display, integration of the system with the RELAP plant simulation and graphical interface, improved operator aids, and an alarm filtering system. 8 refs., 7 figs. (MB)

  20. Analog and mixed-signal electronics

    CERN Document Server

    Stephan, Karl

    2015-01-01

    A practical guide to analog and mixed-signal electronics, with an emphasis on design problems and applications This book provides an in-depth coverage of essential analog and mixed-signal topics such as power amplifiers, active filters, noise and dynamic range, analog-to-digital and digital-to-analog conversion techniques, phase-locked loops, and switching power supplies. Readers will learn the basics of linear systems, types of nonlinearities and their effects, op-amp circuits, the high-gain analog filter-amplifier, and signal generation. The author uses system design examples to motivate

  1. Advances in heuristic signal processing and applications

    CERN Document Server

    Chatterjee, Amitava; Siarry, Patrick

    2013-01-01

    There have been significant developments in the design and application of algorithms for both one-dimensional signal processing and multidimensional signal processing, namely image and video processing, with the recent focus changing from a step-by-step procedure of designing the algorithm first and following up with in-depth analysis and performance improvement to instead applying heuristic-based methods to solve signal-processing problems. In this book the contributing authors demonstrate both general-purpose algorithms and those aimed at solving specialized application problems, with a spec

  2. Signal sciences workshop proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J.V.

    1997-05-01

    This meeting is aimed primarily at signal processing and controls. The technical program for the 1997 Workshop includes a variety of efforts in the Signal Sciences with applications in the Microtechnology Area a new program at LLNL and a future area of application for both Signal/Image Sciences. Special sessions organized by various individuals in Seismic and Optical Signal Processing as well as Micro-Impulse Radar Processing highlight the program, while the speakers at the Signal Processing Applications session discuss various applications of signal processing/control to real world problems. For the more theoretical, a session on Signal Processing Algorithms was organized as well as for the more pragmatic, featuring a session on Real-Time Signal Processing.

  3. Signal sciences workshop. Proceedings

    International Nuclear Information System (INIS)

    Candy, J.V.

    1997-01-01

    This meeting is aimed primarily at signal processing and controls. The technical program for the 1997 Workshop includes a variety of efforts in the Signal Sciences with applications in the Microtechnology Area a new program at LLNL and a future area of application for both Signal/Image Sciences. Special sessions organized by various individuals in Seismic and Optical Signal Processing as well as Micro-Impulse Radar Processing highlight the program, while the speakers at the Signal Processing Applications session discuss various applications of signal processing/control to real world problems. For the more theoretical, a session on Signal Processing Algorithms was organized as well as for the more pragmatic, featuring a session on Real-Time Signal Processing

  4. ECG signal processing

    NARCIS (Netherlands)

    2009-01-01

    A system extracts an ECG signal from a composite signal (308) representing an electric measurement of a living subject. Identification means (304) identify a plurality of temporal segments (309) of the composite signal corresponding to a plurality of predetermined segments (202,204,206) of an ECG

  5. Roles of STATs signaling in cardiovascular diseases.

    Science.gov (United States)

    Kishore, Raj; Verma, Suresh K

    2012-04-01

    In cardiac and many other systems, chronic stress activates avfamily of structurally and functionally conserved receptors and their downstream signaling molecules that entail tyrosine, serine or threonine phosphorylation to transfer the messages to the genetic machinery. However, the activation of the Janus kinases (JAKs) and their downstream signal transducer and activator of transcription (STATs) proteins is both characteristic of and unique to cytokine and growth factor signaling which plays a central role in heart physiology. Dysregulation of JAK-STAT signaling is associated with various cardiovascular diseases. The molecular signaling and specificity of the JAK-STAT pathway are modulated at many levels by distinct regulatory proteins. Here, we review recent studies on the regulation of the STAT signaling pathway that will enhance our ability to design rational therapeutic strategies for stress-induced heart failure.

  6. Signal Processing and Neural Network Simulator

    Science.gov (United States)

    Tebbe, Dennis L.; Billhartz, Thomas J.; Doner, John R.; Kraft, Timothy T.

    1995-04-01

    The signal processing and neural network simulator (SPANNS) is a digital signal processing simulator with the capability to invoke neural networks into signal processing chains. This is a generic tool which will greatly facilitate the design and simulation of systems with embedded neural networks. The SPANNS is based on the Signal Processing WorkSystemTM (SPWTM), a commercial-off-the-shelf signal processing simulator. SPW provides a block diagram approach to constructing signal processing simulations. Neural network paradigms implemented in the SPANNS include Backpropagation, Kohonen Feature Map, Outstar, Fully Recurrent, Adaptive Resonance Theory 1, 2, & 3, and Brain State in a Box. The SPANNS was developed by integrating SAIC's Industrial Strength Neural Networks (ISNN) Software into SPW.

  7. Optimal Signal Quality Index for Photoplethysmogram Signals

    Directory of Open Access Journals (Sweden)

    Mohamed Elgendi

    2016-09-01

    Full Text Available A photoplethysmogram (PPG is a noninvasive circulatory signal related to the pulsatile volume of blood in tissue and is typically collected by pulse oximeters. PPG signals collected via mobile devices are prone to artifacts that negatively impact measurement accuracy, which can lead to a significant number of misleading diagnoses. Given the rapidly increased use of mobile devices to collect PPG signals, developing an optimal signal quality index (SQI is essential to classify the signal quality from these devices. Eight SQIs were developed and tested based on: perfusion, kurtosis, skewness, relative power, non-stationarity, zero crossing, entropy, and the matching of systolic wave detectors. Two independent annotators annotated all PPG data (106 recordings, 60 s each and a third expert conducted the adjudication of differences. The independent annotators labeled each PPG signal with one of the following labels: excellent, acceptable or unfit for diagnosis. All indices were compared using Mahalanobis distance, linear discriminant analysis, quadratic discriminant analysis, and support vector machine with leave-one-out cross-validation. The skewness index outperformed the other seven indices in differentiating between excellent PPG and acceptable, acceptable combined with unfit, and unfit recordings, with overall F 1 scores of 86.0%, 87.2%, and 79.1%, respectively.

  8. Optimal Signal Quality Index for Photoplethysmogram Signals.

    Science.gov (United States)

    Elgendi, Mohamed

    2016-09-22

    A photoplethysmogram (PPG) is a noninvasive circulatory signal related to the pulsatile volume of blood in tissue and is typically collected by pulse oximeters. PPG signals collected via mobile devices are prone to artifacts that negatively impact measurement accuracy, which can lead to a significant number of misleading diagnoses. Given the rapidly increased use of mobile devices to collect PPG signals, developing an optimal signal quality index (SQI) is essential to classify the signal quality from these devices. Eight SQIs were developed and tested based on: perfusion, kurtosis, skewness, relative power, non-stationarity, zero crossing, entropy, and the matching of systolic wave detectors. Two independent annotators annotated all PPG data (106 recordings, 60 s each) and a third expert conducted the adjudication of differences. The independent annotators labeled each PPG signal with one of the following labels: excellent, acceptable or unfit for diagnosis. All indices were compared using Mahalanobis distance, linear discriminant analysis, quadratic discriminant analysis, and support vector machine with leave-one-out cross-validation. The skewness index outperformed the other seven indices in differentiating between excellent PPG and acceptable, acceptable combined with unfit, and unfit recordings, with overall F 1 scores of 86.0%, 87.2%, and 79.1%, respectively.

  9. Global Optimization for Transport Network Expansion and Signal Setting

    OpenAIRE

    Liu, Haoxiang; Wang, David Z. W.; Yue, Hao

    2015-01-01

    This paper proposes a model to address an urban transport planning problem involving combined network design and signal setting in a saturated network. Conventional transport planning models usually deal with the network design problem and signal setting problem separately. However, the fact that network capacity design and capacity allocation determined by network signal setting combine to govern the transport network performance requires the optimal transport planning to consider the two pr...

  10. Second-hand signals

    DEFF Research Database (Denmark)

    Bergenholtz, Carsten

    2014-01-01

    Studies of signaling theory have traditionally focused on the dyadic link between the sender and receiver of the signal. Within a science‐based perspective this framing has led scholars to investigate how patents and publications of firms function as signals. I explore another important type...... used by various agents in their search for and assessment of products and firms. I conclude by arguing how this second‐hand nature of signals goes beyond a simple dyadic focus on senders and receivers of signals, and thus elucidates the more complex interrelations of the various types of agents...

  11. Traffic flow behavior at un-signalized intersection with crossings pedestrians

    Science.gov (United States)

    Khallouk, A.; Echab, H.; Ez-Zahraouy, H.; Lakouari, N.

    2018-02-01

    Mixed traffic flux composed of crossing pedestrians and vehicles extensively exists in cities. To study the characteristics of the interference traffic flux, we develop a pedestrian-vehicle cellular automata model to present the interaction behaviors on a simple cross road. By realizing the fundamental parameters (i.e. injecting rates α1, α2, the extracting rate β and the pedestrian arrival rate αP), simulations are carried out. The vehicular traffic flux is calculated in terms of rates. The effect of the crosswalk can be regarded as a dynamic impurity. The system phase diagrams in the (α1 ,αP) plane are built. It is found that the phase diagrams consist essentially of four phases namely Free Flow, Congested, Maximal Current and Gridlock. The value of the Maximal current phase depends on the extracting rate β, while the Gridlock phase is achieved only when the pedestrians generating rate is higher than a critical value. Furthermore, the effect of vehicles changing lane (Pch1 ,Pch2) and the location of the crosswalk XP on the dynamic characteristics of vehicles flow are investigated. It is found that traffic situation in the system is slightly enhanced if the location of the crosswalks XP is far from the intersection. However, when Pch1, Pch2 increase, the traffic becomes congested and the Gridlock phase enlarges.

  12. Method of signal analysis

    International Nuclear Information System (INIS)

    Berthomier, Charles

    1975-01-01

    A method capable of handling the amplitude and the frequency time laws of a certain kind of geophysical signals is described here. This method is based upon the analytical signal idea of Gabor and Ville, which is constructed either in the time domain by adding an imaginary part to the real signal (in-quadrature signal), or in the frequency domain by suppressing negative frequency components. The instantaneous frequency of the initial signal is then defined as the time derivative of the phase of the analytical signal, and his amplitude, or envelope, as the modulus of this complex signal. The method is applied to three types of magnetospheric signals: chorus, whistlers and pearls. The results obtained by analog and numerical calculations are compared to results obtained by classical systems using filters, i.e. based upon a different definition of the concept of frequency. The precision with which the frequency-time laws are determined leads then to the examination of the principle of the method and to a definition of instantaneous power density spectrum attached to the signal, and to the first consequences of this definition. In this way, a two-dimensional representation of the signal is introduced which is less deformed by the analysis system properties than the usual representation, and which moreover has the advantage of being obtainable practically in real time [fr

  13. Measurand transient signal suppressor

    Science.gov (United States)

    Bozeman, Richard J., Jr. (Inventor)

    1994-01-01

    A transient signal suppressor for use in a controls system which is adapted to respond to a change in a physical parameter whenever it crosses a predetermined threshold value in a selected direction of increasing or decreasing values with respect to the threshold value and is sustained for a selected discrete time interval is presented. The suppressor includes a sensor transducer for sensing the physical parameter and generating an electrical input signal whenever the sensed physical parameter crosses the threshold level in the selected direction. A manually operated switch is provided for adapting the suppressor to produce an output drive signal whenever the physical parameter crosses the threshold value in the selected direction of increasing or decreasing values. A time delay circuit is selectively adjustable for suppressing the transducer input signal for a preselected one of a plurality of available discrete suppression time and producing an output signal only if the input signal is sustained for a time greater than the selected suppression time. An electronic gate is coupled to receive the transducer input signal and the timer output signal and produce an output drive signal for energizing a control relay whenever the transducer input is a non-transient signal which is sustained beyond the selected time interval.

  14. Wnt signaling in cancer

    Science.gov (United States)

    Zhan, T; Rindtorff, N; Boutros, M

    2017-01-01

    Wnt signaling is one of the key cascades regulating development and stemness, and has also been tightly associated with cancer. The role of Wnt signaling in carcinogenesis has most prominently been described for colorectal cancer, but aberrant Wnt signaling is observed in many more cancer entities. Here, we review current insights into novel components of Wnt pathways and describe their impact on cancer development. Furthermore, we highlight expanding functions of Wnt signaling for both solid and liquid tumors. We also describe current findings how Wnt signaling affects maintenance of cancer stem cells, metastasis and immune control. Finally, we provide an overview of current strategies to antagonize Wnt signaling in cancer and challenges that are associated with such approaches. PMID:27617575

  15. Cooperative ethylene receptor signaling

    OpenAIRE

    Liu, Qian; Wen, Chi-Kuang

    2012-01-01

    The gaseous plant hormone ethylene is perceived by a family of five ethylene receptor members in the dicotyledonous model plant Arabidopsis. Genetic and biochemical studies suggest that the ethylene response is suppressed by ethylene receptor complexes, but the biochemical nature of the receptor signal is unknown. Without appropriate biochemical measures to trace the ethylene receptor signal and quantify the signal strength, the biological significance of the modulation of ethylene responses ...

  16. Traffic signal synchronization.

    Science.gov (United States)

    Huang, Ding-wei; Huang, Wei-neng

    2003-05-01

    The benefits of traffic signal synchronization are examined within the cellular automata approach. The microsimulations of traffic flow are obtained with different settings of signal period T and time delay delta. Both numerical results and analytical approximations are presented. For undersaturated traffic, the green-light wave solutions can be realized. For saturated traffic, the correlation among the traffic signals has no effect on the throughput. For oversaturated traffic, the benefits of synchronization are manifest only when stochastic noise is suppressed.

  17. Faster than Nyquist signaling algorithms to silicon

    CERN Document Server

    Dasalukunte, Deepak; Rusek, Fredrik; Anderson, John B

    2014-01-01

    This book addresses the challenges and design trade-offs arising during the hardware design of Faster-than-Nyquist (FTN) signaling transceivers. The authors describe how to design for coexistence between the FTN system described and Orthogonal frequency-division multiplexing (OFDM) systems, enabling readers to design FTN specific processing blocks as add-ons to the conventional transceiver chain.   • Provides a comprehensive introduction to Faster-than-Nyquist (FTN) signaling transceivers, covering both theory and hardware implementation; • Enables readers to design systems that achieve bandwidth efficiency by making better use of the available spectrum resources; • Describes design techniques to achieve 2x improvement in bandwidth usage with similar performance as that of an OFDM system.  

  18. [Detection of surface EMG signal using active electrode].

    Science.gov (United States)

    He, Qinghua; Peng, Chenglin; Wu, Baoming; Wang, He

    2003-09-01

    Research of surface electromyogram(EMG) signal is important in rehabilitation medicine, sport medicine and clinical diagnosis, accurate detection of signal is the base of quantitative analysis of surface EMG signal. In this article were discussed how to reduce possible noise in the detection of surface EMG. Considerations on the design of electrode unit were presented. Instrumentation amplifier AD620 was employed to design a bipolar active electrode for use in surface EMG detection. The experiments showed that active electrode could be used to improve signal/noise ratio, reduce noise and detect surface EMG signal effectively.

  19. Nichtkontinuierliche (zeitdiskrete) Signale

    Science.gov (United States)

    Plaßmann, Wilfried

    Zeitdiskrete Signale werden häufig aus zeitkontinuierlichen Signalen durch Abtastung erzeugt. Dass beide Signale gleichwertig sind, zeigt das Abtasttheorem (Kap. 116) von Shannon, sofern die Bedingung nach (116.2), f_{ab}≈(2{,}2 {\\ldots} 4)\\cdot fg) eingehalten wird. Digitale Signale haben Vorteile: Einfache Speicherung, Weiterverarbeitung in Rechnern, wenig störanfällige Übertragung. Für die Bearbeitung dieser Signale dienen die im Kapitel dargestellten Hilfsmittel: Diskrete Fouriertransformation; Schnelle Fouriertransformation; z-Transformation: Darstellung, Sätze zur z-Transformation, Korrespondenzen zu Zeitfunktionen, Beispiele.

  20. Biomedical signals and systems

    CERN Document Server

    Tranquillo, Joseph V

    2013-01-01

    Biomedical Signals and Systems is meant to accompany a one-semester undergraduate signals and systems course. It may also serve as a quick-start for graduate students or faculty interested in how signals and systems techniques can be applied to living systems. The biological nature of the examples allows for systems thinking to be applied to electrical, mechanical, fluid, chemical, thermal and even optical systems. Each chapter focuses on a topic from classic signals and systems theory: System block diagrams, mathematical models, transforms, stability, feedback, system response, control, time

  1. Radiation signal processing system

    International Nuclear Information System (INIS)

    Bennett, M.; Knoll, G.; Strange, D.

    1980-01-01

    An improved signal processing system for radiation imaging apparatus comprises: a radiation transducer producing transducer signals proportional to apparent spatial coordinates of detected radiation events; means for storing true spatial coordinates corresponding to a plurality of predetermined apparent spatial coordinates relative to selected detected radiation events said means for storing responsive to said transducer signal and producing an output signal representative of said true spatial coordinates; and means for interpolating the true spatial coordinates of the detected radiation events located intermediate the stored true spatial coordinates, said means for interpolating communicating with said means for storing

  2. Digital signal processing

    CERN Document Server

    O'Shea, Peter; Hussain, Zahir M

    2011-01-01

    In three parts, this book contributes to the advancement of engineering education and that serves as a general reference on digital signal processing. Part I presents the basics of analog and digital signals and systems in the time and frequency domain. It covers the core topics: convolution, transforms, filters, and random signal analysis. It also treats important applications including signal detection in noise, radar range estimation for airborne targets, binary communication systems, channel estimation, banking and financial applications, and audio effects production. Part II considers sel

  3. Multimedia signal coding and transmission

    CERN Document Server

    Ohm, Jens-Rainer

    2015-01-01

    This textbook covers the theoretical background of one- and multidimensional signal processing, statistical analysis and modelling, coding and information theory with regard to the principles and design of image, video and audio compression systems. The theoretical concepts are augmented by practical examples of algorithms for multimedia signal coding technology, and related transmission aspects. On this basis, principles behind multimedia coding standards, including most recent developments like High Efficiency Video Coding, can be well understood. Furthermore, potential advances in future development are pointed out. Numerous figures and examples help to illustrate the concepts covered. The book was developed on the basis of a graduate-level university course, and most chapters are supplemented by exercises. The book is also a self-contained introduction both for researchers and developers of multimedia compression systems in industry.

  4. Learning sparse generative models of audiovisual signals

    OpenAIRE

    Monaci, Gianluca; Sommer, Friedrich T.; Vandergheynst, Pierre

    2008-01-01

    This paper presents a novel framework to learn sparse represen- tations for audiovisual signals. An audiovisual signal is modeled as a sparse sum of audiovisual kernels. The kernels are bimodal functions made of synchronous audio and video components that can be positioned independently and arbitrarily in space and time. We design an algorithm capable of learning sets of such audiovi- sual, synchronous, shift-invariant functions by alternatingly solving a coding and a learning pr...

  5. Drought Signaling in Plants

    Indian Academy of Sciences (India)

    depending upon the source and nature of signaling: (i) hormone signal, (ii) .... plants to regulate the rate of transpiration through minor structural .... cell has to keep spending energy (in the form of A TP) to maintain a .... enzymes and proteins in the regulation of cellular metabolism can be determined by either inactivating.

  6. Ubiquitination in apoptosis signaling

    NARCIS (Netherlands)

    van de Kooij, L.W.

    2014-01-01

    The work described in this thesis focuses on ubiquitination and protein degradation, with an emphasis on how these processes regulate apoptosis signaling. More specifically, our aims were: 1. To increase the understanding of ubiquitin-mediated regulation of apoptosis signaling. 2. To identify the E3

  7. Multiresolution signal decomposition schemes

    NARCIS (Netherlands)

    J. Goutsias (John); H.J.A.M. Heijmans (Henk)

    1998-01-01

    textabstract[PNA-R9810] Interest in multiresolution techniques for signal processing and analysis is increasing steadily. An important instance of such a technique is the so-called pyramid decomposition scheme. This report proposes a general axiomatic pyramid decomposition scheme for signal analysis

  8. Optimal fault signal estimation

    NARCIS (Netherlands)

    Stoorvogel, Antonie Arij; Niemann, H.H.; Saberi, A.; Sannuti, P.

    2002-01-01

    We consider here both fault identification and fault signal estimation. Regarding fault identification, we seek either exact or almost fault identification. On the other hand, regarding fault signal estimation, we seek either $H_2$ optimal, $H_2$ suboptimal or Hinfinity suboptimal estimation. By

  9. Signal sampling circuit

    NARCIS (Netherlands)

    Louwsma, S.M.; Vertregt, Maarten

    2011-01-01

    A sampling circuit for sampling a signal is disclosed. The sampling circuit comprises a plurality of sampling channels adapted to sample the signal in time-multiplexed fashion, each sampling channel comprising a respective track-and-hold circuit connected to a respective analogue to digital

  10. Signal sampling circuit

    NARCIS (Netherlands)

    Louwsma, S.M.; Vertregt, Maarten

    2010-01-01

    A sampling circuit for sampling a signal is disclosed. The sampling circuit comprises a plurality of sampling channels adapted to sample the signal in time-multiplexed fashion, each sampling channel comprising a respective track-and-hold circuit connected to a respective analogue to digital

  11. Signal Enhancement with Variable Span Linear Filters

    DEFF Research Database (Denmark)

    Benesty, Jacob; Christensen, Mads Græsbøll; Jensen, Jesper Rindom

    . Variable span filters combine the ideas of optimal linear filters with those of subspace methods, as they involve the joint diagonalization of the correlation matrices of the desired signal and the noise. The book shows how some well-known filter designs, e.g. the minimum distortion, maximum signal...... the time and STFT domains, and, lastly, in time-domain binaural enhancement. In these contexts, the properties of these filters are analyzed in terms of their noise reduction capabilities and desired signal distortion, and the analyses are validated and further explored in simulations....

  12. Bioelectric Signal Measuring System

    Science.gov (United States)

    Guadarrama-Santana, A.; Pólo-Parada, L.; García-Valenzuela, A.

    2015-01-01

    We describe a low noise measuring system based on interdigitated electrodes for sensing bioelectrical signals. The system registers differential voltage measurements in order of microvolts. The base noise during measurements was in nanovolts and thus, the sensing signals presented a very good signal to noise ratio. An excitation voltage of 1Vrms with 10 KHz frequency was applied to an interdigitated capacitive sensor without a material under test and to a mirror device simultaneously. The output signals of both devices was then subtracted in order to obtain an initial reference value near cero volts and reduce parasitic capacitances due to the electronics, wiring and system hardware as well. The response of the measuring system was characterized by monitoring temporal bioelectrical signals in real time of biological materials such as embryo chicken heart cells and bovine suprarenal gland cells.

  13. Acoustic Signals and Systems

    DEFF Research Database (Denmark)

    2008-01-01

    The Handbook of Signal Processing in Acoustics will compile the techniques and applications of signal processing as they are used in the many varied areas of Acoustics. The Handbook will emphasize the interdisciplinary nature of signal processing in acoustics. Each Section of the Handbook...... will present topics on signal processing which are important in a specific area of acoustics. These will be of interest to specialists in these areas because they will be presented from their technical perspective, rather than a generic engineering approach to signal processing. Non-specialists, or specialists...... from different areas, will find the self-contained chapters accessible and will be interested in the similarities and differences between the approaches and techniques used in different areas of acoustics....

  14. Design Methodology - Design Synthesis

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup

    2003-01-01

    Design Methodology is part of our practice and our knowledge about designing, and it has been strongly supported by the establishing and work of a design research community. The aim of this article is to broaden the reader¿s view of designing and Design Methodology. This is done by sketching...... the development of Design Methodology through time and sketching some important approaches and methods. The development is mainly forced by changing industrial condition, by the growth of IT support for designing, but also by the growth of insight into designing created by design researchers.......ABSTRACT Design Methodology shall be seen as our understanding of how to design; it is an early (emerging late 60ies) and original articulation of teachable and learnable methodics. The insight is based upon two sources: the nature of the designed artefacts and the nature of human designing. Today...

  15. Orexin/Hypocretin Signaling.

    Science.gov (United States)

    Kukkonen, Jyrki P

    Orexin/hypocretin peptide (orexin-A and orexin-B) signaling is believed to take place via the two G-protein-coupled receptors (GPCRs), named OX 1 and OX 2 orexin receptors, as described in the previous chapters. Signaling of orexin peptides has been investigated in diverse endogenously orexin receptor-expressing cells - mainly neurons but also other types of cells - and in recombinant cells expressing the receptors in a heterologous manner. Findings in the different systems are partially convergent but also indicate cellular background-specific signaling. The general picture suggests an inherently high degree of diversity in orexin receptor signaling.In the current chapter, I present orexin signaling on the cellular and molecular levels. Discussion of the connection to (potential) physiological orexin responses is only brief since these are in focus of other chapters in this book. The same goes for the post-synaptic signaling mechanisms, which are dealt with in Burdakov: Postsynaptic actions of orexin. The current chapter is organized according to the tissue type, starting from the central nervous system. Finally, receptor signaling pathways are discussed across tissues, cell types, and even species.

  16. Signal flow analysis

    CERN Document Server

    Abrahams, J R; Hiller, N

    1965-01-01

    Signal Flow Analysis provides information pertinent to the fundamental aspects of signal flow analysis. This book discusses the basic theory of signal flow graphs and shows their relation to the usual algebraic equations.Organized into seven chapters, this book begins with an overview of properties of a flow graph. This text then demonstrates how flow graphs can be applied to a wide range of electrical circuits that do not involve amplification. Other chapters deal with the parameters as well as circuit applications of transistors. This book discusses as well the variety of circuits using ther

  17. Designing Material Materialising Design

    DEFF Research Database (Denmark)

    Nicholas, Paul

    2013-01-01

    Designing Material Materialising Design documents five projects developed at the Centre for Information Technology and Architecture (CITA) at the Royal Danish Academy of Fine Arts, School of Architecture. These projects explore the idea that new designed materials might require new design methods....... Focusing on fibre reinforced composites, this book sustains an exploration into the design and making of elastically tailored architectural structures that rely on the use of computational design to predict sensitive interdependencies between geometry and behaviour. Developing novel concepts...

  18. Underwater Acoustic Signal Processing

    National Research Council Canada - National Science Library

    Culver, Richard L; Sibul, Leon H; Bradley, David L

    2007-01-01

    .... The research is directed toward passive sonar detection and classification, continuous wave (CW) and broadband signals, shallow water operation, both platform-mounted and distributed systems, and frequencies below 1 kHz...

  19. Signals and systems

    CERN Document Server

    Rao, K Deergha

    2018-01-01

    This textbook covers the fundamental theories of signals and systems analysis, while incorporating recent developments from integrated circuits technology into its examples. Starting with basic definitions in signal theory, the text explains the properties of continuous-time and discrete-time systems and their representation by differential equations and state space. From those tools, explanations for the processes of Fourier analysis, the Laplace transform, and the z-Transform provide new ways of experimenting with different kinds of time systems. The text also covers the separate classes of analog filters and their uses in signal processing applications. Intended for undergraduate electrical engineering students, chapter sections include exercise for review and practice for the systems concepts of each chapter. Along with exercises, the text includes MATLAB-based examples to allow readers to experiment with signals and systems code on their own. An online repository of the MATLAB code from this textbook can...

  20. Topological signal processing

    CERN Document Server

    Robinson, Michael

    2014-01-01

    Signal processing is the discipline of extracting information from collections of measurements. To be effective, the measurements must be organized and then filtered, detected, or transformed to expose the desired information.  Distortions caused by uncertainty, noise, and clutter degrade the performance of practical signal processing systems. In aggressively uncertain situations, the full truth about an underlying signal cannot be known.  This book develops the theory and practice of signal processing systems for these situations that extract useful, qualitative information using the mathematics of topology -- the study of spaces under continuous transformations.  Since the collection of continuous transformations is large and varied, tools which are topologically-motivated are automatically insensitive to substantial distortion. The target audience comprises practitioners as well as researchers, but the book may also be beneficial for graduate students.

  1. Acoustic MIMO signal processing

    CERN Document Server

    Huang, Yiteng; Chen, Jingdong

    2006-01-01

    A timely and important book addressing a variety of acoustic signal processing problems under multiple-input multiple-output (MIMO) scenarios. It uniquely investigates these problems within a unified framework offering a novel and penetrating analysis.

  2. Ultrahigh bandwidth signal processing

    DEFF Research Database (Denmark)

    Oxenløwe, Leif Katsuo

    2016-01-01

    Optical time lenses have proven to be very versatile for advanced optical signal processing. Based on a controlled interplay between dispersion and phase-modulation by e.g. four-wave mixing, the processing is phase-preserving, an hence useful for all types of data signals including coherent multi......-level modulation founats. This has enabled processing of phase-modulated spectrally efficient data signals, such as orthogonal frequency division multiplexed (OFDM) signa In that case, a spectral telescope system was used, using two time lenses with different focal lengths (chirp rates), yielding a spectral...... regeneratio These operations require a broad bandwidth nonlinear platform, and novel photonic integrated nonlinear platform like aluminum gallium arsenide nano-waveguides used for 1.28 Tbaud optical signal processing will be described....

  3. Traffic Signal Cycle Lengths

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — Traffic signal location list for the town of Chapel Hill. This data set includes light cycle information as well as as intersection information.The Town of Chapel...

  4. Signal processing for smart cards

    Science.gov (United States)

    Quisquater, Jean-Jacques; Samyde, David

    2003-06-01

    In 1998, Paul Kocher showed that when a smart card computes cryptographic algorithms, for signatures or encryption, its consumption or its radiations leak information. The keys or the secrets hidden in the card can then be recovered using a differential measurement based on the intercorrelation function. A lot of silicon manufacturers use desynchronization countermeasures to defeat power analysis. In this article we detail a new resynchronization technic. This method can be used to facilitate the use of a neural network to do the code recognition. It becomes possible to reverse engineer a software code automatically. Using data and clock separation methods, we show how to optimize the synchronization using signal processing. Then we compare these methods with watermarking methods for 1D and 2D signal. The very last watermarking detection improvements can be applied to signal processing for smart cards with very few modifications. Bayesian processing is one of the best ways to do Differential Power Analysis, and it is possible to extract a PIN code from a smart card in very few samples. So this article shows the need to continue to set up effective countermeasures for cryptographic processors. Although the idea to use advanced signal processing operators has been commonly known for a long time, no publication explains that results can be obtained. The main idea of differential measurement is to use the cross-correlation of two random variables and to repeat consumption measurements on the processor to be analyzed. We use two processors clocked at the same external frequency and computing the same data. The applications of our design are numerous. Two measurements provide the inputs of a central operator. With the most accurate operator we can improve the signal noise ratio, re-synchronize the acquisition clock with the internal one, or remove jitter. The analysis based on consumption or electromagnetic measurements can be improved using our structure. At first sight

  5. Source of seismic signals

    Energy Technology Data Exchange (ETDEWEB)

    Frankovskii, B.A.; Khor' yakov, K.A.

    1980-08-30

    Patented is a source of seismic signals consisting of a shock generator with a basic low-voltage and auxillary high-voltage stator coils, a capacitive transformer and control switches. To increase the amplitude of signal excitation a condensor battery and auxillary commutator are introduced into the device, which are connected in parallel and serially into the circuit of the main low-voltage stator coil.

  6. Redox signaling in plants.

    Science.gov (United States)

    Foyer, Christine H; Noctor, Graham

    2013-06-01

    Our aim is to deliver an authoritative and challenging perspective of current concepts in plant redox signaling, focusing particularly on the complex interface between the redox and hormone-signaling pathways that allow precise control of plant growth and defense in response to metabolic triggers and environmental constraints and cues. Plants produce significant amounts of singlet oxygen and other reactive oxygen species (ROS) as a result of photosynthetic electron transport and metabolism. Such pathways contribute to the compartment-specific redox-regulated signaling systems in plant cells that convey information to the nucleus to regulate gene expression. Like the chloroplasts and mitochondria, the apoplast-cell wall compartment makes a significant contribution to the redox signaling network, but unlike these organelles, the apoplast has a low antioxidant-buffering capacity. The respective roles of ROS, low-molecular antioxidants, redox-active proteins, and antioxidant enzymes are considered in relation to the functions of plant hormones such as salicylic acid, jasmonic acid, and auxin, in the composite control of plant growth and defense. Regulation of redox gradients between key compartments in plant cells such as those across the plasma membrane facilitates flexible and multiple faceted opportunities for redox signaling that spans the intracellular and extracellular environments. In conclusion, plants are recognized as masters of the art of redox regulation that use oxidants and antioxidants as flexible integrators of signals from metabolism and the environment.

  7. Transient-Switch-Signal Suppressor

    Science.gov (United States)

    Bozeman, Richard J., Jr.

    1995-01-01

    Circuit delays transmission of switch-opening or switch-closing signal until after preset suppression time. Used to prevent transmission of undesired momentary switch signal. Basic mode of operation simple. Beginning of switch signal initiates timing sequence. If switch signal persists after preset suppression time, circuit transmits switch signal to external circuitry. If switch signal no longer present after suppression time, switch signal deemed transient, and circuit does not pass signal on to external circuitry, as though no transient switch signal. Suppression time preset at value large enough to allow for damping of underlying pressure wave or other mechanical transient.

  8. Signal processing: opportunities for superconductive circuits

    International Nuclear Information System (INIS)

    Ralston, R.W.

    1985-01-01

    Prime motivators in the evolution of increasingly sophisticated communication and detection systems are the needs for handling ever wider signal bandwidths and higher data processing speeds. These same needs drive the development of electronic device technology. Until recently the superconductive community has been tightly focused on digital devices for high speed computers. The purpose of this paper is to describe opportunities and challenges which exist for both analog and digital devices in a less familiar area, that of wideband signal processing. The function and purpose of analog signal-processing components, including matched filters, correlators and Fourier transformers, will be described and examples of superconductive implementations given. A canonic signal-processing system is then configured using these components in combination with analog/digital converters and digital output circuits to highlight the important issues of dynamic range, accuracy and equivalent computation rate. Superconductive circuits hold promise for processing signals of 10-GHz bandwidth. Signal processing systems, however, can be properly designed and implemented only through a synergistic combination of the talents of device physicists, circuit designers, algorithm architects and system engineers. An immediate challenge to the applied superconductivity community is to begin sharing ideas with these other researchers

  9. Signal integrity applied electromagnetics and professional practice

    CERN Document Server

    Russ, Samuel H

    2016-01-01

    This textbook teaches how to design working systems at very high frequencies. It is designed to introduce computer engineers to the design of extremely high speed digital systems. Combining an intuitive, physics-based approach to electromagnetics with a focus on solving realistic problems, the author presents concepts that are essential for computer and electrical engineers today. The book emphasizes an intuitive approach to electromagnetics, and then uses this foundation to show the reader how both physical phenomena can cause signals to propagate incorrectly; and how to solve commonly encountered issues. Emphasis is placed on real problems that the author has encountered in his professional career, integrating problem-solving strategies and real signal-integrity case studies throughout the presentation. Students are challenged to think about managing complex design projects and implementing successful engineering and manufacturing processes. Each chapter includes exercises to test concepts introduced.

  10. Integrated Circuits for Analog Signal Processing

    CERN Document Server

    2013-01-01

      This book presents theory, design methods and novel applications for integrated circuits for analog signal processing.  The discussion covers a wide variety of active devices, active elements and amplifiers, working in voltage mode, current mode and mixed mode.  This includes voltage operational amplifiers, current operational amplifiers, operational transconductance amplifiers, operational transresistance amplifiers, current conveyors, current differencing transconductance amplifiers, etc.  Design methods and challenges posed by nanometer technology are discussed and applications described, including signal amplification, filtering, data acquisition systems such as neural recording, sensor conditioning such as biomedical implants, actuator conditioning, noise generators, oscillators, mixers, etc.   Presents analysis and synthesis methods to generate all circuit topologies from which the designer can select the best one for the desired application; Includes design guidelines for active devices/elements...

  11. Protocell design through modular compartmentalization.

    Science.gov (United States)

    Miller, David; Booth, Paula J; Seddon, John M; Templer, Richard H; Law, Robert V; Woscholski, Rudiger; Ces, Oscar; Barter, Laura M C

    2013-10-06

    De novo synthetic biological design has the potential to significantly impact upon applications such as energy generation and nanofabrication. Current designs for constructing organisms from component parts are typically limited in scope, as they utilize a cut-and-paste ideology to create simple stepwise engineered protein-signalling pathways. We propose the addition of a new design element that segregates components into lipid-bound 'proto-organelles', which are interfaced with response elements and housed within a synthetic protocell. This design is inspired by living cells, which utilize multiple types of signalling molecules to facilitate communication between isolated compartments. This paper presents our design and validation of the components required for a simple multi-compartment protocell machine, for coupling a light transducer to a gene expression system. This represents a general design concept for the compartmentalization of different types of artificial cellular machinery and the utilization of non-protein signal molecules for signal transduction.

  12. To signal or not to signal: that should not be the question.

    Science.gov (United States)

    Faw, Harold W

    2013-10-01

    The purpose of the present research was to examine rates of turn signal use, a positive and potentially valuable means by which drivers can communicate. A second purpose was to explore factors that might impact these rates, including the modeling influence of other drivers. A series of observations involving more than 5600 vehicles making turns were recorded at a variety of intersections in British Columbia, Canada. Though the occurrence of signal use varied widely, ranging from a low of 54% to a high of 95%, the overall rate was 76%. Drivers used turn signals significantly less often when making right as compared with left turns, when traffic volume was higher, and when a designated turning lane was provided. In addition, compared with drivers following another vehicle not using signals, those following a vehicle with turn signals on were significantly more likely to activate their turn signals, suggesting a possible modeling effect. Both internal and external influences on turn signal use by drivers were considered. External factors explored in this research included direction of turn, traffic volume, intersection configuration, and the example of other drivers. It was concluded that the practice of signaling turns merits more research attention, since consistent use of signals is a potential contributor to enhanced safety for all road users. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Signal- and Symbol-based Representations in Computer Vision

    DEFF Research Database (Denmark)

    Krüger, Norbert; Felsberg, Michael

    We discuss problems of signal-- and symbol based representations in terms of three dilemmas which are faced in the design of each vision system. Signal- and symbol-based representations are opposite ends of a spectrum of conceivable design decisions caught at opposite sides of the dilemmas. We make...... inherent problems explicit and describe potential design decisions for artificial visual systems to deal with the dilemmas....

  14. Experimental industrial signal acquisition board in a large scientific device

    Science.gov (United States)

    Zeng, Xiangzhen; Ren, Bin

    2018-02-01

    In order to measure the industrial signal of neutrino experiment, a set of general-purpose industrial data acquisition board has been designed. It includes the function of switch signal input and output, and the function of analog signal input. The main components are signal isolation amplifier and filter circuit, ADC circuit, microcomputer systems and isolated communication interface circuit. Through the practical experiments, it shows that the system is flexible, reliable, convenient and economical, and the system has characters of high definition and strong anti-interference ability. Thus, the system fully meets the design requirements.

  15. A capacitive bioelectrode for recording electrophysiological signals

    International Nuclear Information System (INIS)

    Moreno Garcia, E.; Mujica Ascencio, S.; Rosa Vazquez, J. M.de la; Stolik Isakina, S.

    2012-01-01

    In this paper we describe a gel-free sensor with on-board electrode design, which capacitive couples to the skin to detect the electrical activity in the body. The integrated sensor is manufactured on a standard printed circuit board within 2.2 cm diameter enclosure that can operate through fabric or other insulation. The electrode includes amplification (60db gain) and passive band pass filtering (0.5 to 100 Hz). Active shielding surrounding the sensor plate is used to reduce noise pickup. The input referred noise, measured over the electrode bandwidth is 4 μV rms at 0.2 mm sensor distance, and 16 μV rms at 1.2 mm distance trough two cotton cloths. The bioelectrodes were coupled to the scalp trough hair for EEG signals (with 80 db gain), and coupled to the chest through clothing for ECG signals. The recorded signals show well performance of the designed bielectrode. (Author)

  16. Cellular signalling properties in microcircuits

    DEFF Research Database (Denmark)

    Toledo-Rodriguez, Maria; El Manira, Abdeljabbar; Wallén, Peter

    2005-01-01

    Molecules and cells are the signalling elements in microcircuits. Recent studies have uncovered bewildering diversity in postsynaptic signalling properties in all areas of the vertebrate nervous system. Major effort is now being invested in establishing the specialized signalling properties...

  17. Designing Communication Design

    DEFF Research Database (Denmark)

    Løvlie, Anders Sundnes

    2016-01-01

    Innovating in the field of new media genres requires methods for producing designs that can succeed in being disseminated and used outside of design research labs. This article uses the author's experiences with the development of university courses in communication design to address the research...... question: How can we design courses to give students the competencies they need to work as designers of new media? Based on existing approaches from UX design and other fields, I present a model that has demonstrated its usefulness in the development of commercial products and services. The model...

  18. Quantum signaling game

    International Nuclear Information System (INIS)

    Frackiewicz, Piotr

    2014-01-01

    We present a quantum approach to a signaling game; a special kind of extensive game of incomplete information. Our model is based on quantum schemes for games in strategic form where players perform unitary operators on their own qubits of some fixed initial state and the payoff function is given by a measurement on the resulting final state. We show that the quantum game induced by our scheme coincides with a signaling game as a special case and outputs nonclassical results in general. As an example, we consider a quantum extension of the signaling game in which the chance move is a three-parameter unitary operator whereas the players' actions are equivalent to classical ones. In this case, we study the game in terms of Nash equilibria and refine the pure Nash equilibria adapting to the quantum game the notion of a weak perfect Bayesian equilibrium. (paper)

  19. PKD signaling and pancreatitis

    Science.gov (United States)

    Yuan, Jingzhen; Pandol, Stephen J.

    2016-01-01

    Background Acute pancreatitis is a serious medical disorder with no current therapies directed to the molecular pathogenesis of the disorder. Inflammation, inappropriate intracellular activation of digestive enzymes, and parenchymal acinar cell death by necrosis are the critical pathophysiologic processes of acute pancreatitis. Thus, it is necessary to elucidate the key molecular signals that mediate these pathobiologic processes and develop new therapeutic strategies to attenuate the appropriate signaling pathways in order to improve outcomes for this disease. A novel serine/threonine protein kinase D (PKD) family has emerged as key participants in signal transduction, and this family is increasingly being implicated in the regulation of multiple cellular functions and diseases. Methods This review summarizes recent findings of our group and others regarding the signaling pathway and the biological roles of the PKD family in pancreatic acinar cells. In particular, we highlight our studies of the functions of PKD in several key pathobiologic processes associated with acute pancreatitis in experimental models. Results Our findings reveal that PKD signaling is required for NF-κB activation/inflammation, intracellular zymogen activation, and acinar cell necrosis in rodent experimental pancreatitis. Novel small-molecule PKD inhibitors attenuate the severity of pancreatitis in both in vitro and in vivo experimental models. Further, this review emphasizes our latest advances in the therapeutic application of PKD inhibitors to experimental pancreatitis after the initiation of pancreatitis. Conclusions These novel findings suggest that PKD signaling is a necessary modulator in key initiating pathobiologic processes of pancreatitis, and that it constitutes a novel therapeutic target for treatments of this disorder. PMID:26879861

  20. TOR signalling in plants.

    Science.gov (United States)

    Rexin, Daniel; Meyer, Christian; Robaglia, Christophe; Veit, Bruce

    2015-08-15

    Although the eukaryotic TOR (target of rapamycin) kinase signalling pathway has emerged as a key player for integrating nutrient-, energy- and stress-related cues with growth and metabolic outputs, relatively little is known of how this ancient regulatory mechanism has been adapted in higher plants. Drawing comparisons with the substantial knowledge base around TOR kinase signalling in fungal and animal systems, functional aspects of this pathway in plants are reviewed. Both conserved and divergent elements are discussed in relation to unique aspects associated with an autotrophic mode of nutrition and adaptive strategies for multicellular development exhibited by plants. © 2015 Authors; published by Portland Press Limited.

  1. Genomic signal processing

    CERN Document Server

    Shmulevich, Ilya

    2007-01-01

    Genomic signal processing (GSP) can be defined as the analysis, processing, and use of genomic signals to gain biological knowledge, and the translation of that knowledge into systems-based applications that can be used to diagnose and treat genetic diseases. Situated at the crossroads of engineering, biology, mathematics, statistics, and computer science, GSP requires the development of both nonlinear dynamical models that adequately represent genomic regulation, and diagnostic and therapeutic tools based on these models. This book facilitates these developments by providing rigorous mathema

  2. Design of a Low-Power, Small-Area AEC-Q100-Compliant SENT Transmitter in Signal Conditioning IC for Automotive Pressure and Temperature Complex Sensors in 180 Nm CMOS Technology

    Science.gov (United States)

    Rikhan, Behnam Samadpoor; Kim, Dong-Gyu; Lee, Dong-Soo; Rehman, Muhammad Riaz Ur; Abbasizadeh, Hamed; Asif, Muhammad; Lee, Minjae; Yang, Youngoo; Lee, Kang-Yoon

    2018-01-01

    In this paper, a low-power and small-area Single Edge Nibble Transmission (SENT) transmitter design is proposed for automotive pressure and temperature complex sensor applications. To reduce the cost and size of the hardware, the pressure and temperature information is processed with a single integrated circuit (IC) and transmitted at the same time to the electronic control unit (ECU) through SENT. Due to its digital nature, it is immune to noise, has reduced sensitivity to electromagnetic interference (EMI), and generates low EMI. It requires only one PAD for its connectivity with ECU, and thus reduces the pin requirements, simplifies the connectivity, and minimizes the printed circuit board (PCB) complexity. The design is fully synthesizable, and independent of technology. The finite state machine-based approach is employed for area efficient implementation, and to translate the proposed architecture into hardware. The IC is fabricated in 1P6M 180 nm CMOS process with an area of (116 μm × 116 μm) and 4.314 K gates. The current consumption is 50 μA from a 1.8 V supply with a total 90 μW power. For compliance with AEC-Q100 for automotive reliability, a reverse and over voltage protection circuit is also implemented with human body model (HBM) electro-static discharge (ESD) of +6 kV, reverse voltage of −16 V to 0 V, over voltage of 8.2 V to 16 V, and fabricated area of 330 μm × 680 μm. The extensive testing, measurement, and simulation results prove that the design is fully compliant with SAE J2716 standard. PMID:29757996

  3. Television picture signal processing

    NARCIS (Netherlands)

    1998-01-01

    Field or frame memories are often used in television receivers for video signal processing functions, such as noise reduction and/or flicker reduction. Television receivers also have graphic features such as teletext, menu-driven control systems, multilingual subtitling, an electronic TV-Guide, etc.

  4. Signals: Applying Academic Analytics

    Science.gov (United States)

    Arnold, Kimberly E.

    2010-01-01

    Academic analytics helps address the public's desire for institutional accountability with regard to student success, given the widespread concern over the cost of higher education and the difficult economic and budgetary conditions prevailing worldwide. Purdue University's Signals project applies the principles of analytics widely used in…

  5. Communication Signals in Lizards.

    Science.gov (United States)

    Carpenter, Charles C.

    1983-01-01

    Discusses mechanisms and functional intent of visual communication signals in iguanid/agamid lizards. Demonstrated that lizards communicate with each other by using pushups and head nods and that each species does this in its own way, conveying different types of information. (JN)

  6. Modeling binaural signal detection

    NARCIS (Netherlands)

    Breebaart, D.J.

    2001-01-01

    With the advent of multimedia technology and powerful signal processing systems, audio processing and reproduction has gained renewed interest. Examples of products that have been developed are audio coding algorithms to efficiently store and transmit music and speech, or audio reproduction systems

  7. Quantum cloning and signaling

    International Nuclear Information System (INIS)

    Simon, C.; Weihs, G.; Zeilinger, A.

    1999-01-01

    We discuss the close connections between cloning of quantum states and superluminal signaling. We present an optimal universal cloning machine based on stimulated emission recently proposed by the authors. As an instructive example, we show how a scheme for superluminal communication based on this cloning machine fails. (Authors)

  8. "Utilizing" signal detection theory.

    Science.gov (United States)

    Lynn, Spencer K; Barrett, Lisa Feldman

    2014-09-01

    What do inferring what a person is thinking or feeling, judging a defendant's guilt, and navigating a dimly lit room have in common? They involve perceptual uncertainty (e.g., a scowling face might indicate anger or concentration, for which different responses are appropriate) and behavioral risk (e.g., a cost to making the wrong response). Signal detection theory describes these types of decisions. In this tutorial, we show how incorporating the economic concept of utility allows signal detection theory to serve as a model of optimal decision making, going beyond its common use as an analytic method. This utility approach to signal detection theory clarifies otherwise enigmatic influences of perceptual uncertainty on measures of decision-making performance (accuracy and optimality) and on behavior (an inverse relationship between bias magnitude and sensitivity optimizes utility). A "utilized" signal detection theory offers the possibility of expanding the phenomena that can be understood within a decision-making framework. © The Author(s) 2014.

  9. Processing oscillatory signals by incoherent feedforward loops

    Science.gov (United States)

    Zhang, Carolyn; Wu, Feilun; Tsoi, Ryan; Shats, Igor; You, Lingchong

    From the timing of amoeba development to the maintenance of stem cell pluripotency,many biological signaling pathways exhibit the ability to differentiate between pulsatile and sustained signals in the regulation of downstream gene expression.While networks underlying this signal decoding are diverse,many are built around a common motif, the incoherent feedforward loop (IFFL),where an input simultaneously activates an output and an inhibitor of the output.With appropriate parameters,this motif can generate temporal adaptation,where the system is desensitized to a sustained input.This property serves as the foundation for distinguishing signals with varying temporal profiles.Here,we use quantitative modeling to examine another property of IFFLs,the ability to process oscillatory signals.Our results indicate that the system's ability to translate pulsatile dynamics is limited by two constraints.The kinetics of IFFL components dictate the input range for which the network can decode pulsatile dynamics.In addition,a match between the network parameters and signal characteristics is required for optimal ``counting''.We elucidate one potential mechanism by which information processing occurs in natural networks with implications in the design of synthetic gene circuits for this purpose. This work was partially supported by the National Science Foundation Graduate Research Fellowship (CZ).

  10. Critical nodes in signalling pathways

    DEFF Research Database (Denmark)

    Taniguchi, Cullen M; Emanuelli, Brice; Kahn, C Ronald

    2006-01-01

    Physiologically important cell-signalling networks are complex, and contain several points of regulation, signal divergence and crosstalk with other signalling cascades. Here, we use the concept of 'critical nodes' to define the important junctions in these pathways and illustrate their unique role...... using insulin signalling as a model system....

  11. Distortions in the output signals of conventional spectrum analyzers

    International Nuclear Information System (INIS)

    Njau, E.C.

    1988-08-01

    We show that the output signals of conventional spectrum analysers contain distortions which basically originate from the signal processing performed inside the analysers' frequency convertors. Total elimination of these distortions through normal filtering techniques is difficult owing to the closeness of some of their frequencies to the corresponding frequencies of the required signals. Simple design adjustments that can minimize these distortions are suggested. (author). 7 refs, 2 figs

  12. Digital signal processing using MATLAB

    CERN Document Server

    Schilling, Robert L

    2016-01-01

    Focus on the development, implementation, and application of modern DSP techniques with DIGITAL SIGNAL PROCESSING USING MATLAB(R), 3E. Written in an engaging, informal style, this edition immediately captures your attention and encourages you to explore each critical topic. Every chapter starts with a motivational section that highlights practical examples and challenges that you can solve using techniques covered in the chapter. Each chapter concludes with a detailed case study example, a chapter summary with learning outcomes, and practical homework problems cross-referenced to specific chapter sections for your convenience. DSP Companion software accompanies each book to enable further investigation. The DSP Companion software operates with MATLAB(R) and provides intriguing demonstrations as well as interactive explorations of analysis and design concepts.

  13. Fundamentals of adaptive signal processing

    CERN Document Server

    Uncini, Aurelio

    2015-01-01

    This book is an accessible guide to adaptive signal processing methods that equips the reader with advanced theoretical and practical tools for the study and development of circuit structures and provides robust algorithms relevant to a wide variety of application scenarios. Examples include multimodal and multimedia communications, the biological and biomedical fields, economic models, environmental sciences, acoustics, telecommunications, remote sensing, monitoring, and, in general, the modeling and prediction of complex physical phenomena. The reader will learn not only how to design and implement the algorithms but also how to evaluate their performance for specific applications utilizing the tools provided. While using a simple mathematical language, the employed approach is very rigorous. The text will be of value both for research purposes and for courses of study.

  14. Sinusoidal Representation of Acoustic Signals

    Science.gov (United States)

    Honda, Masaaki

    Sinusoidal representation of acoustic signals has been an important tool in speech and music processing like signal analysis, synthesis and time scale or pitch modifications. It can be applicable to arbitrary signals, which is an important advantage over other signal representations like physical modeling of acoustic signals. In sinusoidal representation, acoustic signals are composed as sums of sinusoid (sine wave) with different amplitudes, frequencies and phases, which is based on the timedependent short-time Fourier transform (STFT). This article describes the principles of acoustic signal analysis/synthesis based on a sinusoid representation with focus on sine waves with rapidly varying frequency.

  15. Reconstruction of ECG signals in presence of corruption.

    Science.gov (United States)

    Ganeshapillai, Gartheeban; Liu, Jessica F; Guttag, John

    2011-01-01

    We present an approach to identifying and reconstructing corrupted regions in a multi-parameter physiological signal. The method, which uses information in correlated signals, is specifically designed to preserve clinically significant aspects of the signals. We use template matching to jointly segment the multi-parameter signal, morphological dissimilarity to estimate the quality of the signal segment, similarity search using features on a database of templates to find the closest match, and time-warping to reconstruct the corrupted segment with the matching template. In experiments carried out on the MIT-BIH Arrhythmia Database, a two-parameter database with many clinically significant arrhythmias, our method improved the classification accuracy of the beat type by more than 7 times on a signal corrupted with white Gaussian noise, and increased the similarity to the original signal, as measured by the normalized residual distance, by more than 2.5 times.

  16. Simulating Terrorism: Credible Commitment, Costly Signaling, and Strategic Behavior

    Science.gov (United States)

    Siegel, David A.; Young, Joseph K.

    2009-01-01

    We present two simulations designed to convey the strategic nature of terrorism and counterterrorism. The first is a simulated hostage crisis, designed primarily to illustrate the concepts of credible commitment and costly signaling. The second explores high-level decision making of both a terrorist group and the state, and is designed to…

  17. Signal replication in a DNA nanostructure

    Science.gov (United States)

    Mendoza, Oscar; Houmadi, Said; Aimé, Jean-Pierre; Elezgaray, Juan

    2017-01-01

    Logic circuits based on DNA strand displacement reaction are the basic building blocks of future nanorobotic systems. The circuits tethered to DNA origami platforms present several advantages over solution-phase versions where couplings are always diffusion-limited. Here we consider a possible implementation of one of the basic operations needed in the design of these circuits, namely, signal replication. We show that with an appropriate preparation of the initial state, signal replication performs in a reproducible way. We also show the existence of side effects concomitant to the high effective concentrations in tethered circuits, such as slow leaky reactions and cross-activation.

  18. Fast digital recorders of signal shaping

    International Nuclear Information System (INIS)

    Meleshko, E.A.

    1997-01-01

    Methodology of fast digital registration and pulse signals through fast-action analog-to-digital converters is considered. Systems of digital recorders: sampling and storage devices and operational memory units are described. Main attention is paid to developing parallel analog-to-digital converters, making it possible to bring the conversion frequencies up to several gigahertzes are described. Parallel-sequential analog-to-digital converters, combining high action with increased accuracy are also considered. Concrete examples of designing universal and specialized digital signal recorders, applied in experimental physics, are presented. 44 refs., 12 figs

  19. An introduction to digital signal processing

    CERN Document Server

    Karl, John H

    1989-01-01

    An Introduction to Digital Signal Processing is written for those who need to understand and use digital signal processing and yet do not wish to wade through a multi-semester course sequence. Using only calculus-level mathematics, this book progresses rapidly through the fundamentals to advanced topics such as iterative least squares design of IIR filters, inverse filters, power spectral estimation, and multidimensional applications--all in one concise volume.This book emphasizes both the fundamental principles and their modern computer implementation. It presents and demonstrates how si

  20. Optimum study designs.

    Science.gov (United States)

    Gu, C; Rao, D C

    2001-01-01

    Because simplistic designs will lead to prohibitively large sample sizes, the optimization of genetic study designs is critical for successfully mapping genes for complex diseases. Creative designs are necessary for detecting and amplifying the usually weak signals for complex traits. Two important outcomes of a study design--power and resolution--are implicitly tied together by the principle of uncertainty. Overemphasis on either one may lead to suboptimal designs. To achieve optimality for a particular study, therefore, practical measures such as cost-effectiveness must be used to strike a balance between power and resolution. In this light, the myriad of factors involved in study design can be checked for their effects on the ultimate outcomes, and the popular existing designs can be sorted into building blocks that may be useful for particular situations. It is hoped that imaginative construction of novel designs using such building blocks will lead to enhanced efficiency in finding genes for complex human traits.

  1. Variable reflectivity signal mirrors and signal response measurements

    International Nuclear Information System (INIS)

    Vine, Glenn de; Shaddock, Daniel A; McClelland, David E

    2002-01-01

    Future gravitational wave detectors will include some form of signal mirror in order to alter the signal response of the device. We introduce interferometer configurations which utilize a variable reflectivity signal mirror allowing a tunable peak frequency and variable signal bandwidth. A detector configured with a Fabry-Perot cavity as the signal mirror is compared theoretically with one using a Michelson interferometer for a signal mirror. A system for the measurement of the interferometer signal responses is introduced. This technique is applied to a power-recycled Michelson interferometer with resonant sideband extraction. We present broadband measurements of the benchtop prototype's signal response for a range of signal cavity detunings. This technique is also applicable to most other gravitational wave detector configurations

  2. Variable reflectivity signal mirrors and signal response measurements

    CERN Document Server

    Vine, G D; McClelland, D E

    2002-01-01

    Future gravitational wave detectors will include some form of signal mirror in order to alter the signal response of the device. We introduce interferometer configurations which utilize a variable reflectivity signal mirror allowing a tunable peak frequency and variable signal bandwidth. A detector configured with a Fabry-Perot cavity as the signal mirror is compared theoretically with one using a Michelson interferometer for a signal mirror. A system for the measurement of the interferometer signal responses is introduced. This technique is applied to a power-recycled Michelson interferometer with resonant sideband extraction. We present broadband measurements of the benchtop prototype's signal response for a range of signal cavity detunings. This technique is also applicable to most other gravitational wave detector configurations.

  3. The Role of Custom Design in ASIC Chips

    National Research Council Canada - National Science Library

    Dally, William

    1998-01-01

    The performance of an ASIC can be greatly improved without increasing design time by judiciously employing a number of custom design techniques, including floorplanning, prerouting critical signals...

  4. Lymphocyte signaling: beyond knockouts.

    Science.gov (United States)

    Saveliev, Alexander; Tybulewicz, Victor L J

    2009-04-01

    The analysis of lymphocyte signaling was greatly enhanced by the advent of gene targeting, which allows the selective inactivation of a single gene. Although this gene 'knockout' approach is often informative, in many cases, the phenotype resulting from gene ablation might not provide a complete picture of the function of the corresponding protein. If a protein has multiple functions within a single or several signaling pathways, or stabilizes other proteins in a complex, the phenotypic consequences of a gene knockout may manifest as a combination of several different perturbations. In these cases, gene targeting to 'knock in' subtle point mutations might provide more accurate insight into protein function. However, to be informative, such mutations must be carefully based on structural and biophysical data.

  5. Sphingosine signaling and atherogenesis

    DEFF Research Database (Denmark)

    Xu, Cang-bao; Hansen-Schwartz, Jacob; Edvinsson, Lars

    2004-01-01

    Sphingosine-1-phosphate (S1P) has diverse biological functions acting inside cells as a second messenger to regulate cell proliferation and survival, and extracellularly, as a ligand for a group of G protein-coupled receptors (GPCRs) named the endothelial differentiation gene (EDG) family. Five...... closely related GPCRs of EDG family (EDG1, EDG3, EDG5, EDG6, and EDG8) have recently been identified as high-affinity S1P receptors. These receptors are coupled via Gi, Gq, G12/13, and Rho. The signaling pathways are linked to vascular cell migration, proliferation, apoptosis, intracellular Ca2......+ mobilization, and expression of adhesion molecules. The formation of an atherosclerotic lesion occurs through activation of cellular events that include monocyte adhesion to the endothelium and vascular smooth muscle cell (VSMC) migration and proliferation. Thus, S1P signaling may play an important role...

  6. NMR signal transducer

    International Nuclear Information System (INIS)

    Kucheryaev, A.G.; Oliferchuk, N.L.

    1975-01-01

    A signal transducer of nuclear magnetic resonance for simultaneously measuring frequency and intensitivity of two various isotope signals, which are in one specimen is described. The transducer represents radiofrequency circuit with two resonance frequences, which is common for two autodyne generators. To decrease measuring time and to increase recording diagram stability the radiofrequency circuit has LC netork, in the inductivity of which investigated specimen is located; a circuit variable capacity is connected in parallel with one of the autodyne generators. Besides the radiofrequency circuit has an inductance coil in series with a standard specimen inside as well as a variable capacitor connected in parallel with the second autodyne generator. An amplitude of oscillation of each resonance frequency is controlled and adjusted separately. The transducer described can be used for the measurement of a nuclei concentration, isotope concentration and for the spin determination

  7. Biomedical signal analysis

    CERN Document Server

    Rangayyan, Rangaraj M

    2015-01-01

    The book will help assist a reader in the development of techniques for analysis of biomedical signals and computer aided diagnoses with a pedagogical examination of basic and advanced topics accompanied by over 350 figures and illustrations. Wide range of filtering techniques presented to address various applications. 800 mathematical expressions and equations. Practical questions, problems and laboratory exercises. Includes fractals and chaos theory with biomedical applications.

  8. The Denver region traffic signal system improvement program : planning for management and operations

    Science.gov (United States)

    2009-04-01

    The Denver Regional Council of Governments (DRCOG) works with over 30 local jurisdictions on the Traffic Signal System Improvement Program (TSSIP), a combination of management and operations strategies designed to time and coordinate traffic signals ...

  9. Performance Analysis of Recurrence Matrix Statistics for the Detection of Deterministic Signals in Noise

    National Research Council Canada - National Science Library

    Michalowicz, Joseph V; Nichols, Jonathan M; Bucholtz, Frank

    2008-01-01

    Understanding the limitations to detecting deterministic signals in the presence of noise, especially additive, white Gaussian noise, is of importance for the design of LPI systems and anti-LPI signal defense...

  10. A battery-operated pilot balloon time-signal generator

    Science.gov (United States)

    Ralph H. Moltzau

    1966-01-01

    Describes the design and construction of a 1-pound, battery-operated, time-signal transmitter, which is usable with portable radio or field telephone circuits for synchronizing multi-theodolite observation of pilot balloons.

  11. Analogue and Mixed-Signal Integrated Circuits for Space Applications

    CERN Document Server

    2014-01-01

    The purpose of AMICSA 2014 (organised in collaboration of ESA and CERN) is to provide an international forum for the presentation and discussion of recent advances in analogue and mixed-signal VLSI design techniques and technologies for space applications.

  12. Outage performance of cognitive radio systems with Improper Gaussian signaling

    KAUST Repository

    Amin, Osama; Abediseid, Walid; Alouini, Mohamed-Slim

    2015-01-01

    design the SU signal by adjusting its transmitted power and the circularity coefficient to minimize the SU outage probability while maintaining a certain PU quality-of-service. Finally, we evaluate the proposed bounds and adaptive algorithms by numerical

  13. Prompting Designers to Design

    DEFF Research Database (Denmark)

    Ahmed, Saeema

    2006-01-01

    Recent research suggest that engineering designers need assistance to understand what information is relevant for their particular design problem. They require guidance in formulating their queries and also to understand what information is relevant for them. This paper presents an approach to pr...

  14. Calcium signaling in liver.

    Science.gov (United States)

    Gaspers, Lawrence D; Thomas, Andrew P

    2005-01-01

    In hepatocytes, hormones linked to the formation of the second messenger inositol 1,4,5-trisphosphate (InsP3) evoke transient increases or spikes in cytosolic free calcium ([Ca2+]i), that increase in frequency with the agonist concentration. These oscillatory Ca2+ signals are thought to transmit the information encoded in the extracellular stimulus to down-stream Ca2+-sensitive metabolic processes. We have utilized both confocal and wide field fluorescence microscopy techniques to study the InsP3-dependent signaling pathway at the cellular and subcellular levels in the intact perfused liver. Typically InsP3-dependent [Ca2+]i spikes manifest as Ca2+ waves that propagate throughout the entire cytoplasm and nucleus, and in the intact liver these [Ca2+]i increases are conveyed through gap junctions to encompass entire lobular units. The translobular movement of Ca2+ provides a means to coordinate the function of metabolic zones of the lobule and thus, liver function. In this article, we describe the characteristics of agonist-evoked [Ca2+]i signals in the liver and discuss possible mechanisms to explain the propagation of intercellular Ca2+ waves in the intact organ.

  15. Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

    Directory of Open Access Journals (Sweden)

    Jessica L. Bell

    2013-05-01

    Full Text Available CCG-1423 and related analogues represent a new class of inhibitors of Rho/MKL1/SRF-mediated gene transcription, a pathway that has been implicated in both cancer and fibrosis. The molecular target for these compounds is unknown. To facilitate its identification, a series of tag-free photoaffinity probes was designed and synthesized, each one containing a photoactivatable group and an acetylenic end group for subsequent attachment to a fluorescent tag using click chemistry. All were confirmed to maintain biological activity in a cell-based assay for inhibition of SRE-Luc expression. The functional activity of the most potent probe 24 was further confirmed in an assay for PC-3 cell migration. Photolysis of 24 in intact PC-3 cells followed by cell lysis, click ligation of a fluorescent dye, and gel electrophoresis revealed specific labeling of a single 24 kDa band that could be blocked with an active competitor. Future work will focus on identifying the labeled protein(s.

  16. A novel signal compression method based on optimal ensemble empirical mode decomposition for bearing vibration signals

    Science.gov (United States)

    Guo, Wei; Tse, Peter W.

    2013-01-01

    Today, remote machine condition monitoring is popular due to the continuous advancement in wireless communication. Bearing is the most frequently and easily failed component in many rotating machines. To accurately identify the type of bearing fault, large amounts of vibration data need to be collected. However, the volume of transmitted data cannot be too high because the bandwidth of wireless communication is limited. To solve this problem, the data are usually compressed before transmitting to a remote maintenance center. This paper proposes a novel signal compression method that can substantially reduce the amount of data that need to be transmitted without sacrificing the accuracy of fault identification. The proposed signal compression method is based on ensemble empirical mode decomposition (EEMD), which is an effective method for adaptively decomposing the vibration signal into different bands of signal components, termed intrinsic mode functions (IMFs). An optimization method was designed to automatically select appropriate EEMD parameters for the analyzed signal, and in particular to select the appropriate level of the added white noise in the EEMD method. An index termed the relative root-mean-square error was used to evaluate the decomposition performances under different noise levels to find the optimal level. After applying the optimal EEMD method to a vibration signal, the IMF relating to the bearing fault can be extracted from the original vibration signal. Compressing this signal component obtains a much smaller proportion of data samples to be retained for transmission and further reconstruction. The proposed compression method were also compared with the popular wavelet compression method. Experimental results demonstrate that the optimization of EEMD parameters can automatically find appropriate EEMD parameters for the analyzed signals, and the IMF-based compression method provides a higher compression ratio, while retaining the bearing defect

  17. Financial signal processing and machine learning

    CERN Document Server

    Kulkarni,Sanjeev R; Dmitry M. Malioutov

    2016-01-01

    The modern financial industry has been required to deal with large and diverse portfolios in a variety of asset classes often with limited market data available. Financial Signal Processing and Machine Learning unifies a number of recent advances made in signal processing and machine learning for the design and management of investment portfolios and financial engineering. This book bridges the gap between these disciplines, offering the latest information on key topics including characterizing statistical dependence and correlation in high dimensions, constructing effective and robust risk measures, and their use in portfolio optimization and rebalancing. The book focuses on signal processing approaches to model return, momentum, and mean reversion, addressing theoretical and implementation aspects. It highlights the connections between portfolio theory, sparse learning and compressed sensing, sparse eigen-portfolios, robust optimization, non-Gaussian data-driven risk measures, graphical models, causal analy...

  18. Acquirement and enhancement of remote speech signals

    Science.gov (United States)

    Lü, Tao; Guo, Jin; Zhang, He-yong; Yan, Chun-hui; Wang, Can-jin

    2017-07-01

    To address the challenges of non-cooperative and remote acoustic detection, an all-fiber laser Doppler vibrometer (LDV) is established. The all-fiber LDV system can offer the advantages of smaller size, lightweight design and robust structure, hence it is a better fit for remote speech detection. In order to improve the performance and the efficiency of LDV for long-range hearing, the speech enhancement technology based on optimally modified log-spectral amplitude (OM-LSA) algorithm is used. The experimental results show that the comprehensible speech signals within the range of 150 m can be obtained by the proposed LDV. The signal-to-noise ratio ( SNR) and mean opinion score ( MOS) of the LDV speech signal can be increased by 100% and 27%, respectively, by using the speech enhancement technology. This all-fiber LDV, which combines the speech enhancement technology, can meet the practical demand in engineering.

  19. Digital signal processing theory and practice

    CERN Document Server

    Rao, K Deergha

    2018-01-01

    The book provides a comprehensive exposition of all major topics in digital signal processing (DSP). With numerous illustrative examples for easy understanding of the topics, it also includes MATLAB-based examples with codes in order to encourage the readers to become more confident of the fundamentals and to gain insights into DSP. Further, it presents real-world signal processing design problems using MATLAB and programmable DSP processors. In addition to problems that require analytical solutions, it discusses problems that require solutions using MATLAB at the end of each chapter. Divided into 13 chapters, it addresses many emerging topics, which are not typically found in advanced texts on DSP. It includes a chapter on adaptive digital filters used in the signal processing problems for faster acceptable results in the presence of changing environments and changing system requirements. Moreover, it offers an overview of wavelets, enabling readers to easily understand the basics and applications of this po...

  20. Large-signal modeling method for power FETs and diodes

    Energy Technology Data Exchange (ETDEWEB)

    Sun Lu; Wang Jiali; Wang Shan; Li Xuezheng; Shi Hui; Wang Na; Guo Shengping, E-mail: sunlu_1019@126.co [School of Electromechanical Engineering, Xidian University, Xi' an 710071 (China)

    2009-06-01

    Under a large signal drive level, a frequency domain black box model of the nonlinear scattering function is introduced into power FETs and diodes. A time domain measurement system and a calibration method based on a digital oscilloscope are designed to extract the nonlinear scattering function of semiconductor devices. The extracted models can reflect the real electrical performance of semiconductor devices and propose a new large-signal model to the design of microwave semiconductor circuits.

  1. Large-signal modeling method for power FETs and diodes

    International Nuclear Information System (INIS)

    Sun Lu; Wang Jiali; Wang Shan; Li Xuezheng; Shi Hui; Wang Na; Guo Shengping

    2009-01-01

    Under a large signal drive level, a frequency domain black box model of the nonlinear scattering function is introduced into power FETs and diodes. A time domain measurement system and a calibration method based on a digital oscilloscope are designed to extract the nonlinear scattering function of semiconductor devices. The extracted models can reflect the real electrical performance of semiconductor devices and propose a new large-signal model to the design of microwave semiconductor circuits.

  2. Signal feedthroughs for the ATLAS barrel and endcap calorimeters

    International Nuclear Information System (INIS)

    Axen, D.; Hackenburg, R.; Hoffmann, A.; Kane, S.; Lissauer, D.; Makowiecki, D.; Muller, T.; Pate, D.; Radeka, V.; Rahm, D.; Rehak, M.; Rescia, S.; Sexton, K.; Sondericker, J.; Birney, P.; Dowling, A.W.; Fincke-Keeler, M.; Hodges, T.; Holness, F.; Honkanen, N.

    2005-01-01

    The function, design, construction, testing, and installation of the signal feedthroughs for the barrel and endcap ATLAS liquid argon calorimeters are described. The feedthroughs provide a high density and radiation hard method to extract over 200 000 signals from the cryogenic environment of the calorimeters using an application of a design based on flexible kapton circuit board transmission lines. A model to describe the frequency dependent behavior of the transmission lines is also presented

  3. The Modular need for the Division Signal Battalion

    Science.gov (United States)

    2017-06-09

    Division Signal Battalion, Leader Development, Organizational Design, Modularity, Force Structure , Army Warfighting Challenge (AWFC) #20 16. SECURITY...Signal Corps men, equipment , and communications installations tailored to fit the situation.”47 In its initial conception, the cellular structure ...force structure than the Division-centric force of the day.”93 30 days after the issuance of this guidance, designs based on the pilot program began

  4. Signals, processes, and systems an interactive multimedia introduction to signal processing

    CERN Document Server

    Karrenberg, Ulrich

    2013-01-01

    This is a very new concept for learning Signal Processing, not only from the physically-based scientific fundamentals, but also from the didactic perspective, based on modern results of brain research. The textbook together with the DVD form a learning system that provides investigative studies and enables the reader to interactively visualize even complex processes. The unique didactic concept is built on visualizing signals and processes on the one hand, and on graphical programming of signal processing systems on the other. The concept has been designed especially for microelectronics, computer technology and communication. The book allows to develop, modify, and optimize useful applications using DasyLab - a professional and globally supported software for metrology and control engineering. With the 3rd edition, the software is also suitable for 64 bit systems running on Windows 7. Real signals can be acquired, processed and played on the sound card of your computer. The book provides more than 200 pre-pr...

  5. Exponential signaling gain at the receptor level enhances signal-to-noise ratio in bacterial chemotaxis.

    Directory of Open Access Journals (Sweden)

    Silke Neumann

    Full Text Available Cellular signaling systems show astonishing precision in their response to external stimuli despite strong fluctuations in the molecular components that determine pathway activity. To control the effects of noise on signaling most efficiently, living cells employ compensatory mechanisms that reach from simple negative feedback loops to robustly designed signaling architectures. Here, we report on a novel control mechanism that allows living cells to keep precision in their signaling characteristics - stationary pathway output, response amplitude, and relaxation time - in the presence of strong intracellular perturbations. The concept relies on the surprising fact that for systems showing perfect adaptation an exponential signal amplification at the receptor level suffices to eliminate slowly varying multiplicative noise. To show this mechanism at work in living systems, we quantified the response dynamics of the E. coli chemotaxis network after genetically perturbing the information flux between upstream and downstream signaling components. We give strong evidence that this signaling system results in dynamic invariance of the activated response regulator against multiplicative intracellular noise. We further demonstrate that for environmental conditions, for which precision in chemosensing is crucial, the invariant response behavior results in highest chemotactic efficiency. Our results resolve several puzzling features of the chemotaxis pathway that are widely conserved across prokaryotes but so far could not be attributed any functional role.

  6. Predators are attracted to the olfactory signals of prey.

    Directory of Open Access Journals (Sweden)

    Nelika K Hughes

    2010-09-01

    Full Text Available Predator attraction to prey social signals can force prey to trade-off the social imperatives to communicate against the profound effect of predation on their future fitness. These tradeoffs underlie theories on the design and evolution of conspecific signalling systems and have received much attention in visual and acoustic signalling modes. Yet while most territorial mammals communicate using olfactory signals and olfactory hunting is widespread in predators, evidence for the attraction of predators to prey olfactory signals under field conditions is lacking.To redress this fundamental issue, we examined the attraction of free-roaming predators to discrete patches of scents collected from groups of two and six adult, male house mice, Mus domesticus, which primarily communicate through olfaction. Olfactorily-hunting predators were rapidly attracted to mouse scent signals, visiting mouse scented locations sooner, and in greater number, than control locations. There were no effects of signal concentration on predator attraction to their prey's signals.This implies that communication will be costly if conspecific receivers and eavesdropping predators are simultaneously attracted to a signal. Significantly, our results also suggest that receivers may be at greater risk of predation when communicating than signallers, as receivers must visit risky patches of scent to perform their half of the communication equation, while signallers need not.

  7. Interception of LPI radar signals

    Science.gov (United States)

    Lee, Jim P.

    1991-11-01

    Most current radars are designed to transmit short duration pulses with relatively high peak power. These radars can be detected easily by the use of relatively modest EW intercept receivers. Three radar functions (search, anti-ship missile (ASM) seeker, and navigation) are examined to evaluate the effectiveness of potential low probability of intercept (LPI) techniques, such as waveform coding, antenna profile control, and power management that a radar may employ against current Electronic Warfare (EW) receivers. The general conclusion is that it is possible to design a LPI radar which is effective against current intercept EW receivers. LPI operation is most easily achieved at close ranges and against a target with a large radar cross section. The general system sensitivity requirement for the detection of current and projected LPI radars is found to be on the order of -100 dBmi which cannot be met by current EW receivers. Finally, three potential LPI receiver architectures, using channelized, superhet, and acousto-optic receivers with narrow RF and video bandwidths are discussed. They have shown some potential in terms of providing the sensitivity and capability in an environment where both conventional and LPI signals are present.

  8. Theory of NMR probe design

    International Nuclear Information System (INIS)

    Schnall, M.D.

    1988-01-01

    The NMR probe is the intrinsic part of the NMR system which allows transmission of a stimulus to a sample and the reception of a resulting signal from a sample. NMR probes are used in both imaging and spectroscopy. Optimal probe design is important to the production of adequate signal/moise. It is important for anyone using NMR techniques to understand how NMR probes work and how to optimize probe design

  9. Pattern theory the stochastic analysis of real-world signals

    CERN Document Server

    Mumford, David

    2010-01-01

    Pattern theory is a distinctive approach to the analysis of all forms of real-world signals. At its core is the design of a large variety of probabilistic models whose samples reproduce the look and feel of the real signals, their patterns, and their variability. Bayesian statistical inference then allows you to apply these models in the analysis of new signals. This book treats the mathematical tools, the models themselves, and the computational algorithms for applying statistics to analyze six representative classes of signals of increasing complexity. The book covers patterns in text, sound

  10. Streamlining digital signal processing a tricks of the trade guidebook

    CERN Document Server

    2012-01-01

    Streamlining Digital Signal Processing, Second Edition, presents recent advances in DSP that simplify or increase the computational speed of common signal processing operations and provides practical, real-world tips and tricks not covered in conventional DSP textbooks. It offers new implementations of digital filter design, spectrum analysis, signal generation, high-speed function approximation, and various other DSP functions. It provides:Great tips, tricks of the trade, secrets, practical shortcuts, and clever engineering solutions from seasoned signal processing professionalsAn assortment.

  11. Frequency-domain method for separating signal and noise

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A new method for separation of signal and noise (SSN) is put forward. Frequency is redefined according to the features of signal and its derivative in the sampl ing time interval, thus double orthogonal basis (DOB) is constructed so that a signal can be precisely signified with a linear combination of low-frequency DOB . Under joint consideration in time domain (TD) and frequency domain (FD), a method on SSN with high accuracy is derived and a matched algorithm is designed and analyzed. This method is applicable to SSN in multiple frequency bands, and convenient in applying signal characteristics in TD and FD synthetically with highe raccuracy.

  12. Frequency-domain method for separating signal and noise

    Institute of Scientific and Technical Information of China (English)

    王正明; 段晓君

    2000-01-01

    A new method for separation of signal and noise (SSN) is put forward. Frequency is redefined according to the features of signal and its derivative in the sampling time interval, thus double orthogonal basis (DOB) is constructed so that a signal can be precisely signified with a linear combination of low-frequency DOB. Under joint consideration in time domain (TD) and frequency domain (FD), a method on SSN with high accuracy is derived and a matched algorithm is designed and analyzed. This method is applicable to SSN in multiple frequency bands, and convenient in applying signal characteristics in TD and FD synthetically with higher accuracy.

  13. Winged design; Befluegeltes Design

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Tilman

    2013-10-15

    Today the wind rotor blades are about 80 meter long. To keep them light and transportable designers and material scientists come up with a number of ideas. Will the carbon fiber prevail against the glass fiber? [German] Ueber 80 Meter messen die laengsten Rotorblaetter heute. Um sie leicht und transportfaehig zu halten, lassen sich Designer und Materialforscher einiges einfallen. Wird sich die Kohlefaser gegen die Glasfaser durchsetzen?.

  14. Pathophysiology of Glucocorticoid Signaling.

    Science.gov (United States)

    Vitellius, Géraldine; Trabado, Séverine; Bouligand, Jérôme; Delemer, Brigitte; Lombès, Marc

    2018-06-01

    Glucocorticoids (GC), such as cortisol or dexamethasone, control various physiological functions, notably those involved in development, metabolism, inflammatory processes and stress, and exert most of their effects upon binding to the glucocorticoid receptor (GR, encoded by NR3C1 gene). GC signaling follows several consecutive steps leading to target gene transactivation, including ligand binding, nuclear translocation of ligand-activated GR complexes, DNA binding, coactivator interaction and recruitment of functional transcriptional machinery. Any step may be impaired and may account for altered GC signaling. Partial or generalized glucocorticoid resistance syndrome may result in a reduced level of functional GR, a decreased hormone affinity and binding, a defect in nuclear GR translocation, a decrease or lack of DNA binding and/or post-transcriptional GR modifications. To date, 26 loss-of-function NR3C1 mutations have been reported in the context of hypertension, hirsutism, adrenal hyperplasia or metabolic disorders. These clinical signs are generally associated with biological features including hypercortisolism without negative regulatory feedback loop on the hypothalamic-pituitary-adrenal axis. Patients had often low plasma aldosterone and renin levels despite hypertension. Only one GR gain-of-function mutation has been described associating Cushing's syndrome phenotype with normal urinary-free cortisol. Some GR polymorphisms (ER22/23EK, GR-9β) have been linked to glucocorticoid resistance and a healthier metabolic profile whereas some others seemed to be associated with GC hypersensitivity (N363S, BclI), increasing cardiovascular risk (diabetes type 2, visceral obesity). This review focuses on the earlier findings on the pathophysiology of GR signaling and presents criteria facilitating identification of novel NR3C1 mutations in selected patients. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  15. Purinergic Signalling: Therapeutic Developments

    Directory of Open Access Journals (Sweden)

    Geoffrey Burnstock

    2017-09-01

    Full Text Available Purinergic signalling, i.e., the role of nucleotides as extracellular signalling molecules, was proposed in 1972. However, this concept was not well accepted until the early 1990’s when receptor subtypes for purines and pyrimidines were cloned and characterised, which includes four subtypes of the P1 (adenosine receptor, seven subtypes of P2X ion channel receptors and 8 subtypes of the P2Y G protein-coupled receptor. Early studies were largely concerned with the physiology, pharmacology and biochemistry of purinergic signalling. More recently, the focus has been on the pathophysiology and therapeutic potential. There was early recognition of the use of P1 receptor agonists for the treatment of supraventricular tachycardia and A2A receptor antagonists are promising for the treatment of Parkinson’s disease. Clopidogrel, a P2Y12 antagonist, is widely used for the treatment of thrombosis and stroke, blocking P2Y12 receptor-mediated platelet aggregation. Diquafosol, a long acting P2Y2 receptor agonist, is being used for the treatment of dry eye. P2X3 receptor antagonists have been developed that are orally bioavailable and stable in vivo and are currently in clinical trials for the treatment of chronic cough, bladder incontinence, visceral pain and hypertension. Antagonists to P2X7 receptors are being investigated for the treatment of inflammatory disorders, including neurodegenerative diseases. Other investigations are in progress for the use of purinergic agents for the treatment of osteoporosis, myocardial infarction, irritable bowel syndrome, epilepsy, atherosclerosis, depression, autism, diabetes, and cancer.

  16. Overlay Spectrum Sharing using Improper Gaussian Signaling

    KAUST Repository

    Amin, Osama

    2016-11-30

    Improper Gaussian signaling (IGS) scheme has been recently shown to provide performance improvements in interference limited networks as opposed to the conventional proper Gaussian signaling (PGS) scheme. In this paper, we implement the IGS scheme in overlay cognitive radio system, where the secondary transmitter broadcasts a mixture of two different signals. The first signal is selected from the PGS scheme to match the primary message transmission. On the other hand, the second signal is chosen to be from the IGS scheme in order to reduce the interference effect on the primary receiver. We then optimally design the overlay cognitive radio to maximize the secondary link achievable rate while satisfying the primary network quality of service requirements. In particular, we consider full and partial channel knowledge scenarios and derive the feasibility conditions of operating the overlay cognitive radio systems. Moreover, we derive the superiority conditions of the IGS schemes over the PGS schemes supported with closed form expressions for the corresponding power distribution and the circularity coefficient and parameters. Simulation results are provided to support our theoretical derivations.

  17. Mixed-signal instrumentation for large-signal device characterization and modelling

    NARCIS (Netherlands)

    Marchetti, M.

    2013-01-01

    This thesis concentrates on the development of advanced large-signal measurement and characterization tools to support technology development, model extraction and validation, and power amplifier (PA) designs that address the newly introduced third and fourth generation (3G and 4G) wideband

  18. Phonocardiography Signal Processing

    CERN Document Server

    Abbas, Abbas K

    2009-01-01

    The auscultation method is an important diagnostic indicator for hemodynamic anomalies. Heart sound classification and analysis play an important role in the auscultative diagnosis. The term phonocardiography refers to the tracing technique of heart sounds and the recording of cardiac acoustics vibration by means of a microphone-transducer. Therefore, understanding the nature and source of this signal is important to give us a tendency for developing a competent tool for further analysis and processing, in order to enhance and optimize cardiac clinical diagnostic approach. This book gives the

  19. Nichtperiodische zeitkontinuierliche Signale

    Science.gov (United States)

    Plaßmann, Wilfried

    Nichtperiodische Signale haben eine große Bedeutung für die Nachrichten- und Datenübertragung, weil Information nur in nichtdeterministischen Signalen enthalten ist (Teil "Nachrichtentechnik", Abschn. 92.4.1). Aber auch für die Energie- und Regelungstechnik sind sie von Interesse, weil sie entweder Ein- und Ausschaltvorgänge erfassen oder den Übergang von einem momentan stationären Zustand in einen neuen darstellen (Kurzschluss im Energieversorgungsnetz, Auftreten einer Störgröße im Regelsystem). Die Fourier- und die Laplacetransformation können bei nichtperiodischen zeitkontinuierlichen Signalen eingesetzt werden.

  20. Generation of earthquake signals

    International Nuclear Information System (INIS)

    Kjell, G.

    1994-01-01

    Seismic verification can be performed either as a full scale test on a shaker table or as numerical calculations. In both cases it is necessary to have an earthquake acceleration time history. This report describes generation of such time histories by filtering white noise. Analogue and digital filtering methods are compared. Different methods of predicting the response spectrum of a white noise signal filtered by a band-pass filter are discussed. Prediction of both the average response level and the statistical variation around this level are considered. Examples with both the IEEE 301 standard response spectrum and a ground spectrum suggested for Swedish nuclear power stations are included in the report

  1. Unique portable signal acquisition/processing station

    International Nuclear Information System (INIS)

    Garron, R.D.; Azevedo, S.G.

    1983-01-01

    At Lawrence Livermore National Laboratory, there are experimental applications requiring digital signal acquisition as well as data reduction and analysis. A prototype Signal Acquisition/Processing Station (SAPS) has been constructed and is currently undergoing tests. The system employs an LSI-11/23 computer with Data Translation analog-to-digital hardware. SAPS is housed in a roll-around cart which has been designed to withstand most subtle EMI/RFI environments. A user-friendly menu allows a user to access powerful data acquisition packages with a minimum of training. The software architecture of SAPS involves two operating systems, each being transparent to the user. Since this is a general purpose workstation with several units being utilized, an emphasis on low cost, reliability, and maintenance was stressed during conception and design. The system is targeted for mid-range frequency data acquisition; between a data logger and a transient digitizer

  2. Interweave Cognitive Radio with Improper Gaussian Signaling

    KAUST Repository

    Hedhly, Wafa

    2018-01-15

    Improper Gaussian signaling (IGS) has proven its ability in improving the performance of underlay and overlay cognitive radio paradigms. In this paper, the interweave cognitive radio paradigm is studied when the cognitive user employs IGS. The instantaneous achievable rate performance of both the primary and secondary users are analyzed for specific secondary user sensing and detection capabilities. Next, the IGS scheme is optimized to maximize the achievable rate secondary user while satisfying a target minimum rate requirement for the primary user. Proper Gaussian signaling (PGS) scheme design is also derived to be used as benchmark of the IGS scheme design. Finally, different numerical results are introduced to show the gain reaped from adopting IGS over PGS under different system parameters. The main advantage of employing IGS is observed at low sensing and detection capabilities of the SU, lower PU direct link and higher SU interference on the PU side.

  3. Visible light communications modulation and signal processing

    CERN Document Server

    Wang, Zhaocheng; Huang, Wei; Xu, Zhengyuan

    2018-01-01

    This informative new book on state-of-the-art visible light communication (VLC) provides, for the first time, a systematical and advanced treatment of modulation and signal processing for VLC. Visible Light Communications: Modulation and Signal Processing offers a practical guide to designing VLC, linking academic research with commercial applications. In recent years, VLC has attracted attention from academia and industry since it has many advantages over the traditional radio frequency, including wide unregulated bandwidth, high security, and low cost. It is a promising complementary technique in 5G and beyond wireless communications, especially in indoor applications. However, lighting constraints have not been fully considered in the open literature when considering VLC system design, and its importance has been underestimated. That’s why this book—written by a team of experts with both academic research experience and industrial development experience in the field—is so welcome. To help readers u...

  4. Dansk Design

    DEFF Research Database (Denmark)

    Dickson, Thomas

    Indhold: Hvad er design?; Hvor kommer dansk design fra?; Produktdesign; Tekstil- og tøjdesign; Design af møbler og boligindretning; Bygningen og design; Arbejdets design; Transportdesign; Offentligt design; Grafisk design; Nye tider og en ny slags design...

  5. A Serpentine Way to Signaling

    Indian Academy of Sciences (India)

    IAS Admin

    the cell. The receptor transfers the signal to intracellular proteins ... and molecular mechanisms of GPCR signaling and how this discovery impacts ..... stabilize GPCR–G-protein interaction and resolve dynamics of ... elucidation stages. Kobilka.

  6. Biological signals classification and analysis

    CERN Document Server

    Kiasaleh, Kamran

    2015-01-01

    This authored monograph presents key aspects of signal processing analysis in the biomedical arena. Unlike wireless communication systems, biological entities produce signals with underlying nonlinear, chaotic nature that elude classification using the standard signal processing techniques, which have been developed over the past several decades for dealing primarily with standard communication systems. This book separates what is random from that which appears to be random, and yet is truly deterministic with random appearance. At its core, this work gives the reader a perspective on biomedical signals and the means to classify and process such signals. In particular, a review of random processes along with means to assess the behavior of random signals is also provided. The book also includes a general discussion of biological signals in order to demonstrate the inefficacy of the well-known techniques to correctly extract meaningful information from such signals. Finally, a thorough discussion of recently ...

  7. Two-dimensional signal analysis

    CERN Document Server

    Garello, René

    2010-01-01

    This title sets out to show that 2-D signal analysis has its own role to play alongside signal processing and image processing.Concentrating its coverage on those 2-D signals coming from physical sensors (such as radars and sonars), the discussion explores a 2-D spectral approach but develops the modeling of 2-D signals and proposes several data-oriented analysis techniques for dealing with them. Coverage is also given to potential future developments in this area.

  8. Wireless data signal transmission system

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention relates to a method for providing a radio frequency signal for transmission, a system for providing a radio frequency signal for transmission and a method for wireless data transmission between a transmitter and a receiver.......The present invention relates to a method for providing a radio frequency signal for transmission, a system for providing a radio frequency signal for transmission and a method for wireless data transmission between a transmitter and a receiver....

  9. Metabolic Signaling and Therapy of Lung Cancer

    Science.gov (United States)

    2013-09-01

    report are those of the author(s) and should not be construed as an official Department of the Army position, policy or decision unless so designated by...which makes them attractive therapeutic targets. However, the development of targeted agents in lung cancer is still in its infancy, despite the...notion that metabolites can act as signaling molecules in distant metabolic pathways is gaining significant attentionand support (Figure 1A). Some of the

  10. Large-Scale Transit Signal Priority Implementation

    OpenAIRE

    Lee, Kevin S.; Lozner, Bailey

    2018-01-01

    In 2016, the District Department of Transportation (DDOT) deployed Transit Signal Priority (TSP) at 195 intersections in highly urbanized areas of Washington, DC. In collaboration with a broader regional implementation, and in partnership with the Washington Metropolitan Area Transit Authority (WMATA), DDOT set out to apply a systems engineering–driven process to identify, design, test, and accept a large-scale TSP system. This presentation will highlight project successes and lessons learned.

  11. Astrocytes in endocannabinoid signalling.

    Science.gov (United States)

    Navarrete, Marta; Díez, Adolfo; Araque, Alfonso

    2014-10-19

    Astrocytes are emerging as integral functional components of synapses, responding to synaptically released neurotransmitters and regulating synaptic transmission and plasticity. Thus, they functionally interact with neurons establishing tripartite synapses: a functional concept that refers to the existence of communication between astrocytes and neurons and its crucial role in synaptic function. Here, we discuss recent evidence showing that astrocytes are involved in the endocannabinoid (ECB) system, responding to exogenous cannabinoids as well as ECBs through activation of type 1 cannabinoid receptors, which increase intracellular calcium and stimulate the release of glutamate that modulates synaptic transmission and plasticity. We also discuss the consequences of ECB signalling in tripartite synapses on the astrocyte-mediated regulation of synaptic function, which reveal novel properties of synaptic regulation by ECBs, such as the spatially controlled dual effect on synaptic strength and the lateral potentiation of synaptic efficacy. Finally, we discuss the potential implications of ECB signalling for astrocytes in brain pathology and animal behaviour. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  12. Salicylic acid signaling inhibits apoplastic reactive oxygen species signaling.

    Science.gov (United States)

    Xu, Enjun; Brosché, Mikael

    2014-06-04

    Reactive oxygen species (ROS) are used by plants as signaling molecules during stress and development. Given the amount of possible challenges a plant face from their environment, plants need to activate and prioritize between potentially conflicting defense signaling pathways. Until recently, most studies on signal interactions have focused on phytohormone interaction, such as the antagonistic relationship between salicylic acid (SA)-jasmonic acid and cytokinin-auxin. In this study, we report an antagonistic interaction between SA signaling and apoplastic ROS signaling. Treatment with ozone (O3) leads to a ROS burst in the apoplast and induces extensive changes in gene expression and elevation of defense hormones. However, Arabidopsis thaliana dnd1 (defense no death1) exhibited an attenuated response to O3. In addition, the dnd1 mutant displayed constitutive expression of defense genes and spontaneous cell death. To determine the exact process which blocks the apoplastic ROS signaling, double and triple mutants involved in various signaling pathway were generated in dnd1 background. Simultaneous elimination of SA-dependent and SA-independent signaling components from dnd1 restored its responsiveness to O3. Conversely, pre-treatment of plants with SA or using mutants that constitutively activate SA signaling led to an attenuation of changes in gene expression elicited by O3. Based upon these findings, we conclude that plants are able to prioritize the response between ROS and SA via an antagonistic action of SA and SA signaling on apoplastic ROS signaling.

  13. Grating geophone signal processing based on wavelet transform

    Science.gov (United States)

    Li, Shuqing; Zhang, Huan; Tao, Zhifei

    2008-12-01

    Grating digital geophone is designed based on grating measurement technique benefiting averaging-error effect and wide dynamic range to improve weak signal detected precision. This paper introduced the principle of grating digital geophone and its post signal processing system. The signal acquisition circuit use Atmega 32 chip as core part and display the waveform on the Labwindows through the RS232 data link. Wavelet transform is adopted this paper to filter the grating digital geophone' output signal since the signal is unstable. This data processing method is compared with the FIR filter that widespread use in current domestic. The result indicates that the wavelet algorithm has more advantages and the SNR of seismic signal improve obviously.

  14. A Computer- Based Digital Signal Processing for Nuclear Scintillator Detectors

    International Nuclear Information System (INIS)

    Ashour, M.A.; Abo Shosha, A.M.

    2000-01-01

    In this paper, a Digital Signal Processing (DSP) Computer-based system for the nuclear scintillation signals with exponential decay is presented. The main objective of this work is to identify the characteristics of the acquired signals smoothly, this can be done by transferring the signal environment from random signal domain to deterministic domain using digital manipulation techniques. The proposed system consists of two major parts. The first part is the high performance data acquisition system (DAQ) that depends on a multi-channel Logic Scope. Which is interfaced with the host computer through the General Purpose Interface Board (GPIB) Ver. IEEE 488.2. Also, a Graphical User Interface (GUI) has been designed for this purpose using the graphical programming facilities. The second of the system is the DSP software Algorithm which analyses, demonstrates, monitoring these data to obtain the main characteristics of the acquired signals; the amplitude, the pulse count, the pulse width, decay factor, and the arrival time

  15. Signal Adaptive System for Space/Spatial-Frequency Analysis

    Directory of Open Access Journals (Sweden)

    Veselin N. Ivanović

    2009-01-01

    Full Text Available This paper outlines the development of a multiple-clock-cycle implementation (MCI of a signal adaptive two-dimensional (2D system for space/spatial-frequency (S/SF signal analysis. The design is based on a method for improved S/SF representation of the analyzed 2D signals, also proposed here. The proposed MCI design optimizes critical design performances related to hardware complexity, making it a suitable system for real time implementation on an integrated chip. Additionally, the design allows the implemented system to take a variable number of clock cycles (CLKs (the only necessary ones regarding desirable—2D Wigner distribution-presentation of autoterms in different frequency-frequency points during the execution. This ability represents a major advantage of the proposed design which helps to optimize the time required for execution and produce an improved, cross-terms-free S/SF signal representation. The design has been verified by a field-programmable gate array (FPGA circuit design, capable of performing S/SF analysis of 2D signals in real time.

  16. Novel Signal Noise Reduction Method through Cluster Analysis, Applied to Photoplethysmography.

    Science.gov (United States)

    Waugh, William; Allen, John; Wightman, James; Sims, Andrew J; Beale, Thomas A W

    2018-01-01

    Physiological signals can often become contaminated by noise from a variety of origins. In this paper, an algorithm is described for the reduction of sporadic noise from a continuous periodic signal. The design can be used where a sample of a periodic signal is required, for example, when an average pulse is needed for pulse wave analysis and characterization. The algorithm is based on cluster analysis for selecting similar repetitions or pulses from a periodic single. This method selects individual pulses without noise, returns a clean pulse signal, and terminates when a sufficiently clean and representative signal is received. The algorithm is designed to be sufficiently compact to be implemented on a microcontroller embedded within a medical device. It has been validated through the removal of noise from an exemplar photoplethysmography (PPG) signal, showing increasing benefit as the noise contamination of the signal increases. The algorithm design is generalised to be applicable for a wide range of physiological (physical) signals.

  17. Software for biomedical engineering signal processing laboratory experiments.

    Science.gov (United States)

    Tompkins, Willis J; Wilson, J

    2009-01-01

    In the early 1990's we developed a special computer program called UW DigiScope to provide a mechanism for anyone interested in biomedical digital signal processing to study the field without requiring any other instrument except a personal computer. There are many digital filtering and pattern recognition algorithms used in processing biomedical signals. In general, students have very limited opportunity to have hands-on access to the mechanisms of digital signal processing. In a typical course, the filters are designed non-interactively, which does not provide the student with significant understanding of the design constraints of such filters nor their actual performance characteristics. UW DigiScope 3.0 is the first major update since version 2.0 was released in 1994. This paper provides details on how the new version based on MATLAB! works with signals, including the filter design tool that is the programming interface between UW DigiScope and processing algorithms.

  18. Piezoresistor design and applications

    CERN Document Server

    Doll, Joseph C

    2013-01-01

    This book is a comprehensive guide to piezoresistive MEMS sensor design. Piezoresistors transduce mechanical loads into electrical signals via a resistance change, and comprise a substantial portion of the commercial MEMS sensors market. Applications of piezoresistors include strain gauges, accelerometers, pressure sensors, force sensors, chemical sensors and resonators. This book also: ·         Demonstrates how the latest piezoresistor models and optimization techniques can be integrated for high performance piezoresistor design ·         Covers in detail piezoresistor sensitivity and noise models, signal conditioning, fabrication processes, low-power design and numerical optimization techniques ·         Provides an up-to-date discussion of alternative piezoresistive materials and MEMS transduction techniques ·         Explores in detail the tradeoffs in size, performance and complexity between piezoresistive sensing and popular alternatives (capacitive, piezoelectric an...

  19. Engineering satellite-based navigation and timing global navigation satellite systems, signals, and receivers

    CERN Document Server

    Betz, J

    2016-01-01

    This book describes the design and performance analysis of satnav systems, signals, and receivers. It also provides succinct descriptions and comparisons of all the world’s satnav systems. Its comprehensive and logical structure addresses all satnav signals and systems in operation and being developed. Engineering Satellite-Based Navigation and Timing: Global Navigation Satellite Systems, Signals, and Receivers provides the technical foundation for designing and analyzing satnav signals, systems, and receivers. Its contents and structure address all satnav systems and signals: legacy, modernized, and new. It combines qualitative information with detailed techniques and analyses, providing a comprehensive set of insights and engineering tools for this complex multidisciplinary field. Part I describes system and signal engineering including orbital mechanics and constellation design, signal design principles and underlying considerations, link budgets, qua tifying receiver performance in interference, and e...

  20. Signals and systems for dummies

    CERN Document Server

    Wickert, Mark

    2013-01-01

    Getting mixed signals in your signals and systems course? The concepts covered in a typical signals and systems course are often considered by engineering students to be some of the most difficult to master. Thankfully, Signals & Systems For Dummies is your intuitive guide to this tricky course, walking you step-by-step through some of the more complex theories and mathematical formulas in a way that is easy to understand. From Laplace Transforms to Fourier Analyses, Signals & Systems For Dummies explains in plain English the difficult concepts that can trip you up

  1. Detection of signals in noise

    CERN Document Server

    Whalen, Anthony D; Declaris, Nicholas

    1971-01-01

    Detection of Signals in Noise serves as an introduction to the principles and applications of the statistical theory of signal detection. The book discusses probability and random processes; narrowband signals, their complex representation, and their properties described with the aid of the Hilbert transform; and Gaussian-derived processes. The text also describes the application of hypothesis testing for the detection of signals and the fundamentals required for statistical detection of signals in noise. Problem exercises, references, and a supplementary bibliography are included after each c

  2. Multimodal signal variation in space and time : how important is matching a signal with its signaler?

    OpenAIRE

    Taylor, Ryan C.; Klein, Barrett; Stein, Joey; Ryan, Michael J.

    2011-01-01

    Multimodal signals (acoustic+visual) are known to be used by many anuran amphibians during courtship displays. The relative degree to which each signal component influences female mate choice, however, remains poorly understood. In this study we used a robotic frog with an inflating vocal sac and acoustic playbacks to document responses of female túngara frogs to unimodal signal components (acoustic and visual). We then tested female responses to a synchronous multimodal signal. Finally, we t...

  3. Systematic Design of Slow Light Waveguides

    DEFF Research Database (Denmark)

    Wang, Fengwen

    it is vulnerable to manufacturing disorders. This thesis aims to design novel waveguides to alleviate signal distortions and propagation loss using optimization methodologies, and to explore the design robustness with respect to manufacturing imperfections. To alleviate the signal distortions in waveguides...

  4. Purinergic signalling and diabetes

    DEFF Research Database (Denmark)

    Burnstock, Geoffrey; Novak, Ivana

    2013-01-01

    , and common and divergent roles of receptors for nucleotides and nucleosides in different organ systems will be given. This integrated picture will aid our understanding of the challenges of the potential and currently used drugs targeted to specific organ/cells or disorders associated with diabetes.......The pancreas is an organ with a central role in nutrient breakdown, nutrient sensing and release of hormones regulating whole body nutrient homeostasis. In diabetes mellitus, the balance is broken-cells can be starving in the midst of plenty. There are indications that the incidence of diabetes...... type 1 and 2, and possibly pancreatogenic diabetes, is rising globally. Events leading to insulin secretion and action are complex, but there is emerging evidence that intracellular nucleotides and nucleotides are not only important as intracellular energy molecules but also as extracellular signalling...

  5. Mechanical engineers' handbook, design, instrumentation, and controls

    CERN Document Server

    Kutz, Myer

    2015-01-01

    Full coverage of electronics, MEMS, and instrumentation andcontrol in mechanical engineering This second volume of Mechanical Engineers' Handbookcovers electronics, MEMS, and instrumentation and control, givingyou accessible and in-depth access to the topics you'll encounterin the discipline: computer-aided design, product design formanufacturing and assembly, design optimization, total qualitymanagement in mechanical system design, reliability in themechanical design process for sustainability, life-cycle design,design for remanufacturing processes, signal processing, dataacquisition and dis

  6. Wavelet analysis for nonstationary signals

    International Nuclear Information System (INIS)

    Penha, Rosani Maria Libardi da

    1999-01-01

    Mechanical vibration signals play an important role in anomalies identification resulting of equipment malfunctioning. Traditionally, Fourier spectral analysis is used where the signals are assumed to be stationary. However, occasional transient impulses and start-up process are examples of nonstationary signals that can be found in mechanical vibrations. These signals can provide important information about the equipment condition, as early fault detection. The Fourier analysis can not adequately be applied to nonstationary signals because the results provide data about the frequency composition averaged over the duration of the signal. In this work, two methods for nonstationary signal analysis are used: Short Time Fourier Transform (STFT) and wavelet transform. The STFT is a method of adapting Fourier spectral analysis for nonstationary application to time-frequency domain. To have a unique resolution throughout the entire time-frequency domain is its main limitation. The wavelet transform is a new analysis technique suitable to nonstationary signals, which handles the STFT drawbacks, providing multi-resolution frequency analysis and time localization in a unique time-scale graphic. The multiple frequency resolutions are obtained by scaling (dilatation/compression) the wavelet function. A comparison of the conventional Fourier transform, STFT and wavelet transform is made applying these techniques to: simulated signals, arrangement rotor rig vibration signal and rotate machine vibration signal Hanning window was used to STFT analysis. Daubechies and harmonic wavelets were used to continuos, discrete and multi-resolution wavelet analysis. The results show the Fourier analysis was not able to detect changes in the signal frequencies or discontinuities. The STFT analysis detected the changes in the signal frequencies, but with time-frequency resolution problems. The wavelet continuos and discrete transform demonstrated to be a high efficient tool to detect

  7. Fluorescence signalling of the transition metal ions: Design strategy ...

    Indian Academy of Sciences (India)

    Unknown

    strategy based on the choice of the fluorophore component. N B SANKARAN, S ... skill for the development of fluorosensors of this kind. Further, the ... salts of the transition metal ions have been used for studying the influence of the metal ions.

  8. Bi-alphabetic pulse compression radar signal design

    Indian Academy of Sciences (India)

    Bi-alphabetic radar; Hamming scan; back-tracking; merit factor; ... of 14.08, 12.10, 9.85, 8.85, 8.83, 8.86, 8.58 and 8.50 respectively. Beyond n ˆ 59 but below n ˆ 117, the highest merit factor available is 9.56. Known high merit ... subjected to dual ternary±binary interpretation to facilitate a coincidence detection scheme.

  9. Seismic signals hard clipping overcoming

    Science.gov (United States)

    Olszowa, Paula; Sokolowski, Jakub

    2018-01-01

    In signal processing the clipping is understand as the phenomenon of limiting the signal beyond certain threshold. It is often related to overloading of a sensor. Two particular types of clipping are being recognized: soft and hard. Beyond the limiting value soft clipping reduces the signal real gain while the hard clipping stiffly sets the signal values at the limit. In both cases certain amount of signal information is lost. Obviously if one possess the model which describes the considered signal and the threshold value (which might be slightly more difficult to obtain in the soft clipping case), the attempt of restoring the signal can be made. Commonly it is assumed that the seismic signals take form of an impulse response of some specific system. This may lead to belief that the sine wave may be the most appropriate to fit in the clipping period. However, this should be tested. In this paper the possibility of overcoming the hard clipping in seismic signals originating from a geoseismic station belonging to an underground mine is considered. A set of raw signals will be hard-clipped manually and then couple different functions will be fitted and compared in terms of least squares. The results will be then analysed.

  10. Design Innovation and Fashion Cycles.

    OpenAIRE

    Pesendorfer, Wolfgang

    1995-01-01

    A model of fashion cycles is developed in which fashion is used as a signalling device in a "dating-game". We assume that there is a designer (monopolist) who can create new designs at a positive fixed cost and zero marginal cost. Designs are durable commodities. We show the existence of equilibria of the following form: Every T periods a new design is innovated. Over time the price of the design falls and it spreads to more and more agents. Once sufficiently many agents own the design it is ...

  11. Pleiotrophin Signaling Through PTNR in Breast Cancer

    National Research Council Canada - National Science Library

    Powers, Ciaron

    2001-01-01

    ... of intracellular signaling cascades. The pleiotrophin signaling pathway is known to be important in angiogenesis and breast cancer growth, but the exact mechanisms of pleiotrophin signaling remain undefined...

  12. Sensing Methods for Detecting Analog Television Signals

    Science.gov (United States)

    Rahman, Mohammad Azizur; Song, Chunyi; Harada, Hiroshi

    This paper introduces a unified method of spectrum sensing for all existing analog television (TV) signals including NTSC, PAL and SECAM. We propose a correlation based method (CBM) with a single reference signal for sensing any analog TV signals. In addition we also propose an improved energy detection method. The CBM approach has been implemented in a hardware prototype specially designed for participating in Singapore TV white space (WS) test trial conducted by Infocomm Development Authority (IDA) of the Singapore government. Analytical and simulation results of the CBM method will be presented in the paper, as well as hardware testing results for sensing various analog TV signals. Both AWGN and fading channels will be considered. It is shown that the theoretical results closely match with those from simulations. Sensing performance of the hardware prototype will also be presented in fading environment by using a fading simulator. We present performance of the proposed techniques in terms of probability of false alarm, probability of detection, sensing time etc. We also present a comparative study of the various techniques.

  13. Applied Chaos Level Test for Validation of Signal Conditions Underlying Optimal Performance of Voice Classification Methods

    Science.gov (United States)

    Liu, Boquan; Polce, Evan; Sprott, Julien C.; Jiang, Jack J.

    2018-01-01

    Purpose: The purpose of this study is to introduce a chaos level test to evaluate linear and nonlinear voice type classification method performances under varying signal chaos conditions without subjective impression. Study Design: Voice signals were constructed with differing degrees of noise to model signal chaos. Within each noise power, 100…

  14. GPS antenna designs

    Science.gov (United States)

    Laube, Samuel J. P.

    1987-05-01

    Application of the current GPS NAVSTAR system to civilian service requires that a right hand, circularly polarized, -160 dBW spread spectrum signal be received from an orbiting satellite, where the antenna environment is also moving. This presents a design challenge when inexpensive antennas are desired. The intent of this survey is to provide information on the antennas mentioned and to construct and test prototypes to determine whether the choice made by the industry, the quadrifilar helix, is the best. The helix antenna is currently the low cost standard for GPS. Prototype versions were constructed using 12 gauge wire and subminiature coaxial hardline. The constructed antennas were tested using a signal generator and a reference turnstile. A spectrum analyzer was used to measure the level of the received signal.

  15. Digitally programmable signal generator

    International Nuclear Information System (INIS)

    Priatko, G.J.; Kaskey, J.A.

    1988-01-01

    A digitally programmable signal generator (DPSG) includes a first memory from which data is written into a second memory formed of n banks. Each bank includes four memories and a multiplexer, the banks being read once during each time frame, the read-out bits being multiplexed and fed out serially in synchronism with a plurality of clock pulses occuring during a time frame. The resulting serial bit streams may be fed in parallel to a digital-to-analog converter. The DPSG can be used in applications such as Atomic Vapor Laser Isotope Separation (AVLIS) to create an optimal match between the process laser's spectral profile and that of the vaporized material, optical telecommunications, non-optical telecommunication in the microwave and radio spectrum, radar, electronic countermeasures, high speed computer interconnects, local area networks, high definition video transport and the multiplexing of large quantities of slow digital memory into high speed data streams. This invention extends the operation of DPSGs into the GHz range. (author)

  16. Volcanic signals in oceans

    KAUST Repository

    Stenchikov, Georgiy L.

    2009-08-22

    Sulfate aerosols resulting from strong volcanic explosions last for 2–3 years in the lower stratosphere. Therefore it was traditionally believed that volcanic impacts produce mainly short-term, transient climate perturbations. However, the ocean integrates volcanic radiative cooling and responds over a wide range of time scales. The associated processes, especially ocean heat uptake, play a key role in ongoing climate change. However, they are not well constrained by observations, and attempts to simulate them in current climate models used for climate predictions yield a range of uncertainty. Volcanic impacts on the ocean provide an independent means of assessing these processes. This study focuses on quantification of the seasonal to multidecadal time scale response of the ocean to explosive volcanism. It employs the coupled climate model CM2.1, developed recently at the National Oceanic and Atmospheric Administration\\'s Geophysical Fluid Dynamics Laboratory, to simulate the response to the 1991 Pinatubo and the 1815 Tambora eruptions, which were the largest in the 20th and 19th centuries, respectively. The simulated climate perturbations compare well with available observations for the Pinatubo period. The stronger Tambora forcing produces responses with higher signal-to-noise ratio. Volcanic cooling tends to strengthen the Atlantic meridional overturning circulation. Sea ice extent appears to be sensitive to volcanic forcing, especially during the warm season. Because of the extremely long relaxation time of ocean subsurface temperature and sea level, the perturbations caused by the Tambora eruption could have lasted well into the 20th century.

  17. Leading Public Design

    DEFF Research Database (Denmark)

    Bason, Christian

    at all levels have taken up a variety of approaches inspired by the field of design, often in response to growing pressures to innovate. But how these approaches influence public innovation – how they change the roles of public managers, how they help managers generate new ideas and solutions...... – and whether, as some have suggested, they might signal the rise of new governance models or paradigms – these issues have not, with perhaps a few exceptions, been rigorously explored. In this thesis, I explore these issues by examining the experiences of public managers who have pioneered the use of design...... approaches. More specifically, I confront three questions: • Characterizing design practice: Within public sector organizations, what does the application of design approaches entail? Why do public managers look to and commission design, and what tools, techniques, processes and methods are brought into play...

  18. Sonic Interaction Design

    DEFF Research Database (Denmark)

    ) challenges these prevalent approaches by considering sound as an active medium that can enable novel sensory and social experiences through interactive technologies. This book offers an overview of the emerging SID research, discussing theories, methods, and practices, with a focus on the multisensory......Sound is an integral part of every user experience but a neglected medium in design disciplines. Design of an artifact’s sonic qualities is often limited to the shaping of functional, representational, and signaling roles of sound. The interdisciplinary field of sonic interaction design (SID...... aspects of sonic experience. Sonic Interaction Design gathers contributions from scholars, artists, and designers working at the intersections of fields ranging from electronic music to cognitive science. They offer both theoretical considerations of key themes and case studies of products and systems...

  19. Seismic signal and noise on Europa

    Science.gov (United States)

    Panning, Mark; Stähler, Simon; Bills, Bruce; Castillo Castellanos, Jorge; Huang, Hsin-Hua; Husker, Allen; Kedar, Sharon; Lorenz, Ralph; Pike, William T.; Schmerr, Nicholas; Tsai, Victor; Vance, Steven

    2017-10-01

    Seismology is one of our best tools for detailing interior structure of planetary bodies, and a seismometer is included in the baseline and threshold mission design for the upcoming Europa Lander mission. Guiding mission design and planning for adequate science return, though, requires modeling of both the anticipated signal and noise. Assuming ice seismicity on Europa behaves according to statistical properties observed in Earth catalogs and scaling cumulative seismic moment release to the moon, we can simulate long seismic records and estimate background noise and peak signal amplitudes (Panning et al., 2017). This suggests a sensitive instrument comparable to many broadband terrestrial instruments or the SP instrument from the InSight mission to Mars will be able to record signals, while high frequency geophones are likely inadequate. We extend this analysis to also begin incorporation of spatial and temporal variation due to the tidal cycle, which can help inform landing site selection. We also begin exploration of how chaotic terrane at the bottom of the ice shell and inter-ice heterogeneities (i.e. internal melt structures) may affect anticipated seismic observations using 2D numerical seismic simulations.M. P. Panning, S. C. Stähler, H.-H. Huang, S. D. Vance, S. Kedar, V. C. Tsai, W. T. Pike, R. D. Lorenz, “Expected seismicity and the seismic noise environment of Europa,” J. Geophys. Res., in revision, 2017.

  20. Multimodal signalling in estrildid finches

    DEFF Research Database (Denmark)

    Gomes, A. C. R.; Funghi, C.; Soma, M.

    2017-01-01

    Sexual traits (e.g. visual ornaments, acoustic signals, courtship behaviour) are often displayed together as multimodal signals. Some hypotheses predict joint evolution of different sexual signals (e.g. to increase the efficiency of communication) or that different signals trade off with each other...... (e.g. due to limited resources). Alternatively, multiple signals may evolve independently for different functions, or to communicate different information (multiple message hypothesis). We evaluated these hypotheses with a comparative study in the family Estrildidae, one of the largest songbird...... compromise, but generally courtship dance also evolved independently from other signals. Instead of correlated evolution, we found that song, dance and colour are each related to different socio-ecological traits. Song complexity evolved together with ecological generalism, song performance with investment...

  1. Semi-classical signal analysis

    KAUST Repository

    Laleg-Kirati, Taous-Meriem

    2012-09-30

    This study introduces a new signal analysis method, based on a semi-classical approach. The main idea in this method is to interpret a pulse-shaped signal as a potential of a Schrödinger operator and then to use the discrete spectrum of this operator for the analysis of the signal. We present some numerical examples and the first results obtained with this method on the analysis of arterial blood pressure waveforms. © 2012 Springer-Verlag London Limited.

  2. Paracrine signaling in a bacterium.

    Science.gov (United States)

    López, Daniel; Vlamakis, Hera; Losick, Richard; Kolter, Roberto

    2009-07-15

    Cellular differentiation is triggered by extracellular signals that cause target cells to adopt a particular fate. Differentiation in bacteria typically involves autocrine signaling in which all cells in the population produce and respond to the same signal. Here we present evidence for paracrine signaling in bacterial populations-some cells produce a signal to which only certain target cells respond. Biofilm formation in Bacillus involves two centrally important signaling molecules, ComX and surfactin. ComX triggers the production of surfactin. In turn, surfactin causes a subpopulation of cells to produce an extracellular matrix. Cells that produced surfactin were themselves unable to respond to it. Likewise, once surfactin-responsive cells commenced matrix production, they no longer responded to ComX and could not become surfactin producers. Insensitivity to ComX was the consequence of the extracellular matrix as mutant cells unable to make matrix responded to both ComX and surfactin. Our results demonstrate that extracellular signaling was unidirectional, with one subpopulation producing a signal and a different subpopulation responding to it. Paracrine signaling in a bacterial population ensures the maintenance, over generations, of particular cell types even in the presence of molecules that would otherwise cause those cells to differentiate into other cell types.

  3. The Evolution of Covert Signaling.

    Science.gov (United States)

    Smaldino, Paul E; Flamson, Thomas J; McElreath, Richard

    2018-03-20

    Human sociality depends upon the benefits of mutual aid and extensive communication. However, diverse norms and preferences complicate mutual aid, and ambiguity in meaning hinders communication. Here we demonstrate that these two problems can work together to enhance cooperation through the strategic use of deliberately ambiguous signals: covert signaling. Covert signaling is the transmission of information that is accurately received by its intended audience but obscured when perceived by others. Such signals may allow coordination and enhanced cooperation while also avoiding the alienation or hostile reactions of individuals with different preferences. Although the empirical literature has identified potential mechanisms of covert signaling, such as encryption in humor, there is to date no formal theory of its dynamics. We introduce a novel mathematical model to assess when a covert signaling strategy will evolve, as well as how receiver attitudes coevolve with covert signals. Covert signaling plausibly serves an important function in facilitating within-group cooperative assortment by allowing individuals to pair up with similar group members when possible and to get along with dissimilar ones when necessary. This mechanism has broad implications for theories of signaling and cooperation, humor, social identity, political psychology, and the evolution of human cultural complexity.

  4. Signal anomaly detection and characterization

    International Nuclear Information System (INIS)

    Morgenstern, V.M.; Upadhyaya, B.R.; Gloeckler, O.

    1988-08-01

    As part of a comprehensive signal validation system, we have developed a signal anomaly detector, without specifically establishing the cause of the anomaly. A signal recorded from process instrumentation is said to have an anomaly, if during steady-state operation, the deviation in the level of the signal, its root-mean-square (RMS) value, or its statistical distribution changes by a preset value. This deviation could be an unacceptable increase or a decrease in the quantity being monitored. An anomaly in a signal may be characterized by wideband or single-frequency noise, bias error, pulse-type error, nonsymmetric behavior, or a change in the signal bandwidth. Various signatures can be easily computed from data samples and compared against specified threshold values. We want to point out that in real processes, pulses can appear with different time widths, and at different rates of change of the signal. Thus, in characterizing an anomaly as a pulse-type, the fastest pulse width is constrained by the signal sampling interval. For example, if a signal is sampled at 100 Hz, we will not be able to detect pulses occurring at kHz rates. Discussion with utility and Combustion Engineering personnel indicated that it is not practical to detect pulses having a narrow time width. 9 refs., 11 figs., 8 tabs

  5. Thermal resonance in signal transmission

    International Nuclear Information System (INIS)

    Reigada, Ramon; Sarmiento, Antonio; Lindenberg, Katja

    2001-01-01

    We use temperature tuning to control signal propagation in simple one-dimensional arrays of masses connected by hard anharmonic springs and with no local potentials. In our numerical model a sustained signal is applied at one site of a chain immersed in a thermal environment and the signal-to-noise ratio is measured at each oscillator. We show that raising the temperature can lead to enhanced signal propagation along the chain, resulting in thermal resonance effects akin to the resonance observed in arrays of bistable systems

  6. Thermal resonance in signal transmission

    Energy Technology Data Exchange (ETDEWEB)

    Reigada, Ramon; Sarmiento, Antonio; Lindenberg, Katja

    2001-06-01

    We use temperature tuning to control signal propagation in simple one-dimensional arrays of masses connected by hard anharmonic springs and with no local potentials. In our numerical model a sustained signal is applied at one site of a chain immersed in a thermal environment and the signal-to-noise ratio is measured at each oscillator. We show that raising the temperature can lead to enhanced signal propagation along the chain, resulting in thermal resonance effects akin to the resonance observed in arrays of bistable systems.

  7. Contract design

    International Nuclear Information System (INIS)

    Bradley, P.

    2006-01-01

    The current state of the electric power industry in Ontario was discussed with particular reference to the procurement of contracts and why the Ontario Power Authority (OPA) must be contracting to resolve many of Ontario's electricity issues. As Ontario increasingly relies on imports and natural gas-fired generation, the price of electricity continues to rise given that supply is at a low level. In addition to the generation gap, there are also several transmission constrained areas in Ontario, particularly in the Greater Toronto Area (GTA). The OPA announced 2 projects totalling 1900 MW to relieve congestion. According to the Independent Electricity System Operator (IESO), the total potential opportunity for new generation by 2015 is about 5,000 to 7,000 megawatts. OPA is expected to launch procurement processes for up to 1000 MW of cogeneration, 250 MW of province-wide conservation initiatives, 1900 MW of generation in the western part of the GTA, and 600 MW of generation in downtown Toronto. New nuclear capacity is also anticipated in addition to renewables and conservation/demand management (CDM) initiatives. The OPA's competitive procurement processes will include requests for expressions of interest, requests for qualifications and requests for proposals. The challenge of balancing the technical complexities and realities of procuring generation assets with the need for a fair procurement process was discussed. Contracts will be designed to react to market signals and will include 3 styles: tariff style, tolling style and standard offer contract. OPA will make every effort to balance generator and ratepayer interests. 6 figs

  8. Jupiter energetic particle experiment ESAD proton sensor design

    International Nuclear Information System (INIS)

    Gruhn, C.R.; Higbie, P.R.

    1977-12-01

    A proton sensor design for the Jupiter Energetic Particle Experiment is described. The sensor design uses avalanche multiplication in order to lower the effective energy threshold. A complete signal-to-noise analysis is given for this design

  9. Long-distance digital signal transfers between trigger system and TOF system of BES III

    International Nuclear Information System (INIS)

    Liu Guangdong; Liu Shubin; An Qi

    2007-01-01

    This article introduces a design of digital signals communication between the trigger system and the TOF system of BES III. The design can support the BES III successfully, which is based on fiber digital communication, FPGA etc. (authors)

  10. Signal Enhancement with Variable Span Linear Filters

    DEFF Research Database (Denmark)

    Benesty, Jacob; Christensen, Mads Græsbøll; Jensen, Jesper Rindom

    This book introduces readers to the novel concept of variable span speech enhancement filters, and demonstrates how it can be used for effective noise reduction in various ways. Further, the book provides the accompanying Matlab code, allowing readers to easily implement the main ideas discussed....... Variable span filters combine the ideas of optimal linear filters with those of subspace methods, as they involve the joint diagonalization of the correlation matrices of the desired signal and the noise. The book shows how some well-known filter designs, e.g. the minimum distortion, maximum signal......-to-noise ratio, Wiener, and tradeoff filters (including their new generalizations) can be obtained using the variable span filter framework. It then illustrates how the variable span filters can be applied in various contexts, namely in single-channel STFT-based enhancement, in multichannel enhancement in both...

  11. Signal enhancement with variable span linear filters

    CERN Document Server

    Benesty, Jacob; Jensen, Jesper R

    2016-01-01

    This book introduces readers to the novel concept of variable span speech enhancement filters, and demonstrates how it can be used for effective noise reduction in various ways. Further, the book provides the accompanying Matlab code, allowing readers to easily implement the main ideas discussed. Variable span filters combine the ideas of optimal linear filters with those of subspace methods, as they involve the joint diagonalization of the correlation matrices of the desired signal and the noise. The book shows how some well-known filter designs, e.g. the minimum distortion, maximum signal-to-noise ratio, Wiener, and tradeoff filters (including their new generalizations) can be obtained using the variable span filter framework. It then illustrates how the variable span filters can be applied in various contexts, namely in single-channel STFT-based enhancement, in multichannel enhancement in both the time and STFT domains, and, lastly, in time-domain binaural enhancement. In these contexts, the properties of ...

  12. Managing Emergency Situations in the Smart City: The Smart Signal

    Directory of Open Access Journals (Sweden)

    Ángel Asensio

    2015-06-01

    Full Text Available In a city there are numerous items, many of them unnoticed but essential; this is the case of the signals. Signals are considered objects with reduced technological interest, but in this paper we prove that making them smart and integrating in the IoT (Internet of Things could be a relevant contribution to the Smart City. This paper presents the concept of Smart Signal, as a device conscious of its context, with communication skills, able to offer the best message to the user, and as a ubiquitous element that contributes with information to the city. We present the design considerations and a real implementation and validation of the system in one of the most challenging environments that may exist in a city: a tunnel. The main advantages of the Smart Signal are the improvement of the actual functionality of the signal providing new interaction capabilities with users and a new sensory mechanism of the Smart City.

  13. Chemical signaling between plants and plant-pathogenic bacteria.

    Science.gov (United States)

    Venturi, Vittorio; Fuqua, Clay

    2013-01-01

    Studies of chemical signaling between plants and bacteria in the past have been largely confined to two models: the rhizobial-legume symbiotic association and pathogenesis between agrobacteria and their host plants. Recent studies are beginning to provide evidence that many plant-associated bacteria undergo chemical signaling with the plant host via low-molecular-weight compounds. Plant-produced compounds interact with bacterial regulatory proteins that then affect gene expression. Similarly, bacterial quorum-sensing signals result in a range of functional responses in plants. This review attempts to highlight current knowledge in chemical signaling that takes place between pathogenic bacteria and plants. This chemical communication between plant and bacteria, also referred to as interkingdom signaling, will likely become a major research field in the future, as it allows the design of specific strategies to create plants that are resistant to plant pathogens.

  14. Managing Emergency Situations in the Smart City: The Smart Signal.

    Science.gov (United States)

    Asensio, Ángel; Blanco, Teresa; Blasco, Rubén; Marco, Álvaro; Casas, Roberto

    2015-06-18

    In a city there are numerous items, many of them unnoticed but essential; this is the case of the signals. Signals are considered objects with reduced technological interest, but in this paper we prove that making them smart and integrating in the IoT (Internet of Things) could be a relevant contribution to the Smart City. This paper presents the concept of Smart Signal, as a device conscious of its context, with communication skills, able to offer the best message to the user, and as a ubiquitous element that contributes with information to the city. We present the design considerations and a real implementation and validation of the system in one of the most challenging environments that may exist in a city: a tunnel. The main advantages of the Smart Signal are the improvement of the actual functionality of the signal providing new interaction capabilities with users and a new sensory mechanism of the Smart City.

  15. Tunable signal processing in synthetic MAP kinase cascades.

    Science.gov (United States)

    O'Shaughnessy, Ellen C; Palani, Santhosh; Collins, James J; Sarkar, Casim A

    2011-01-07

    The flexibility of MAPK cascade responses enables regulation of a vast array of cell fate decisions, but elucidating the mechanisms underlying this plasticity is difficult in endogenous signaling networks. We constructed insulated mammalian MAPK cascades in yeast to explore how intrinsic and extrinsic perturbations affect the flexibility of these synthetic signaling modules. Contrary to biphasic dependence on scaffold concentration, we observe monotonic decreases in signal strength as scaffold concentration increases. We find that augmenting the concentration of sequential kinases can enhance ultrasensitivity and lower the activation threshold. Further, integrating negative regulation and concentration variation can decouple ultrasensitivity and threshold from the strength of the response. Computational analyses show that cascading can generate ultrasensitivity and that natural cascades with different kinase concentrations are innately biased toward their distinct activation profiles. This work demonstrates that tunable signal processing is inherent to minimal MAPK modules and elucidates principles for rational design of synthetic signaling systems. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Monitoring of electric-cardio signals based on DSP

    Science.gov (United States)

    Yan, Yi-xin; Sun, Hui-nan; Lv, Shuang

    2008-10-01

    Monitoring of electric-cardio signals is the most direct method of discovering heart diseases. This article presents an electric-cardio signal acquisition and processing system based on DSP. According to the features of electric-cardio signals, the proposed system uses the AgCl electrode as electric-cardio signals sensor, and acquires analog signals with AD620 as the prepositional amplifier, and the digital system equipped is with TMS320LF2407A DSP. The design of digital filter and the analysis of heart rate variation are realized by programming in the DSP. Finally the ECG is obtained with P and T waves along with obvious QRS multi-wave characteristics. The system has low power dissipation, low cost and high precision, which meets the requirements for medical instruments.

  17. 2012 Proceedings of the International Conference on Communications, Signal Processing, and Systems

    CERN Document Server

    Wang, Wei; Mu, Jiasong; Liang, Jing; Zhang, Baoju; Pi, Yiming; Zhao, Chenglin

    2012-01-01

    Communications, Signal Processing, and Systems is a collection of contributions coming out of the International Conference on Communications, Signal Processing, and Systems (CSPS) held October 2012. This book provides the state-of-art developments of Communications, Signal Processing, and Systems, and their interactions in multidisciplinary fields, such as Smart Grid. The book also examines Radar Systems, Sensor Networks, Radar Signal Processing, Design and Implementation of Signal Processing Systems and Applications. Written by experts and students in the fields of Communications, Signal Processing, and Systems.

  18. Oversampling ad converters with improved signal transfer functions

    CERN Document Server

    Pandita, Bupesh

    2011-01-01

    This book describes techniques for designing complex, discrete-time I""IGBP ADCs with signal-transfer functions that significantly filter interfering signals. The book provides an understanding of theory, issues, and implementation of discrete complex I""IGBP ADCs. The concepts developed in each chapter are further explained by applying them to a target application of I""IGBP ADCs in DTV receivers.

  19. Computer evaluation of random signals from vibration acoustic diagnostics

    International Nuclear Information System (INIS)

    Bahna, J.

    1979-01-01

    Definitions and relations are shown for the calculation of the characteristics of random signals used, such as the amplitude probability density, correlation functions and power spectral densities. The methods are described of digitizing a continuous signal for calculating the above characteristics. The algorithm of the fast Fourier transformation was used in the calculation. The design is described of a system whose essential part is an analog-to-digital converter. The system software is also described. (J.B.)

  20. Signals analysis of fluxgate array for wire rope defaults

    International Nuclear Information System (INIS)

    Gu Wei; Chu Jianxin

    2005-01-01

    In order to detecting the magnetic leakage fields of the wire rope defaults, a transducer made up of the fluxgate array is designed, and a series of the characteristic values of wire rope defaults signals are defined. By processing the characteristic signals, the LF or LMA of wire rope are distinguished, and the default extent is estimated. The experiment results of the new method for detecting the wire rope faults are introduced