WorldWideScience

Sample records for corrected approval letter

  1. Letters

    OpenAIRE

    Chauvet, Jean-Marie; Fetzer, James; Waltzman, Rand

    1985-01-01

    Letters to the editor on genetic epistemology; a reaction to Nilsson's article "AI Prepares for 2001" and a reaction to the Kosko letter to the editor (Fall 1984, p. 5). Also a note on the AAAI-84 Profile and "Meta-Ravioli" (use of the prefix "meta").

  2. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    At the request of you, our readers, this year we are introducing a "Letters to the Editor" column. We value your comments, positive and negative, on our layout, content and pictures and will make continuous efforts to improve our magazine. We welcome your comments and views on all aspects of China. [We reserve the right to edit for content, clarity or length.]If your letter or e-mail is published, you receive a gift!

  3. EFL Students’ Preferences toward the Lecturer’s Corrective Feedback in Business Letters Writing

    Directory of Open Access Journals (Sweden)

    La Ode Sanu

    2016-12-01

    Full Text Available This study aimed to investigate; the students’ preferences toward the lecturer’s corrective feedback in the business letter writing and their reasons why they preferred for particular corrective feedback types. A case study was used by involving 15 EFL students who enrolled the Business Correspondence Course. The questionnaire and interview were used as the research instruments. This study revealed that; (1 the students preferred to receive lecturer correction (M=5.00, followed by lecturer-students conferencing (M=4.13, peer-correction (M=2.73, error identification (M=2.00, lecturer commentary (M=1.93, and self-correction (M=1.27. (2 the students’ reasons at choosing the lecturer correction were getting the directly good correction from the lecturer, which it would be used as the reference/guide for further improvements both linguistic accuracy and business letter organization. In lecturer-students conferencing, beside they got good correction and grateful appreciation from both their lecturer and other students, they could learn and share the knowledge of errors made together; however they ashamed their linguistics errors, low ability and knowledge in formatting good business letter could be known by others. In peer-correction, the students got the unsatisfied and satisfied corrective feedback from their peers; and they were doubt with their peers’ ability and knowledge in giving correction. In Error identification and lecturer commentary, it was difficult for the students to diagnose the real errors and to correct them. Finally, the reasons of self-correction were useless and unsatisfied to evaluate their own work since they had limited ability and knowledge in formatting the business letter writing effectively.

  4. Closure Letter Report for Corrective Action Unit 496: Buried Rocket Site - Antelope Lake

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2007-05-01

    A Streamlined Approach for Environmental Restoration (SAFER) Plan for investigation and closure of CAU 496, Corrective Action Site (CAS) TA-55-008-TAAL (Buried Rocket), at the Tonopah Test Range (TTR), was approved by the Nevada Department of Environmental Protection (NDEP) on July 21,2004. Approval to transfer CAS TA-55-008-TAAL from CAU 496 to CAU 4000 (No Further Action Sites) was approved by NDEP on December 21, 2005, based on the assumption that the rocket did not present any environmental concern. The approval letter included the following condition: ''NDEP understands, from the NNSA/NSO letter dated November 30,2005, that a search will be conducted for the rocket during the planned characterization of other sites at the Tonopah Test Range and, if found, the rocket will be removed as a housekeeping measure''. NDEP and U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office personnel located the rocket on Mid Lake during a site visit to TTR, and a request to transfer CAS TA-55-008-TAAL from CAU 4000 back to CAU 496 was approved by NDEP on September 11,2006. CAS TA-55-008-TAAL was added to the ''Federal Facility Agreement and Consent Order'' of 1996, based on an interview with a retired TTR worker in 1993. The original interview documented that a rocket was launched from Area 9 to Antelope Lake and was never recovered due to the high frequency of rocket tests being conducted during this timeframe. The interviewee recalled the rocket being an M-55 or N-55 (the M-50 ''Honest John'' rocket was used extensively at TTR from the 1960s to early 1980s). A review of previously conducted interviews with former TTR personnel indicated that the interviewees confused information from several sites. The location of the CAU 496 rocket on Mid Lake is directly south of the TTR rocket launch facility in Area 9 and is consistent with information gathered on the lost rocket during recent

  5. Letters

    Science.gov (United States)

    2001-03-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE Contents: Force on a pendulum Sound slows down Bond is back Force on a pendulum The simple pendulum has been used by several educationalists for investigating the patterns of thinking among students and their observations that Aristotelian thinking persists among students at college level. I had also considered the simple pendulum in my 1985 letter in Physics Today [1], so I was interested to read the test given by Lenka Czudková and Jana Musilová [2]. When students were asked to draw net forces acting on the particle at various positions, 31.9% of students believed that the net force was tangential to the particle's path the whole time. To me this is no surprise because in our derivation of the equation for the period of a simple pendulum we assume that the unbalanced sine component provides the restoring force for the harmonic motion of the bob. Of course, Czudková and Musilová's question asked students for the net force on the particle, not the component. The student's answer fits well with the logic of the equilibrium of forces and the parallelogram law. Lastly, let me bring out the similarity between the student's answer and the thinking of George Gamow. He used to call positrons 'donkey' electrons because of their displacement against the applied force, before Paul Dirac termed them positrons. Victor Weisskeptf told me this anecdote in a letter in May 1982. References [1] Sathe D 1985 Phys. Today 38 144 [2] Czudková L and Musilová J 2000 Phys. Educ. 35 428 Dileep V Sathe Dadawala Jr College, Pune, India Sound slows down Without wanting to stir up more trouble amongst the already muddy waters of Physics teaching, consider how many times you have heard (or, more worryingly, read) this: 'Sound waves travel faster in a denser material' But...The velocity of simple longitudinal waves in a bulk medium is given by v = (K/ρ)1/2 where K is

  6. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Dear Editor, I am a loyal reader of your magazine. I read Issue No.9 (March 2, 2006) and was deeply impressed by the articles on tobacco. Tobacco is indeed a big problem in China. Well, I would like to introduce, through your letters page, an association closely related to tobacco control. It is called Green Breathing Association, a student organization in Xiamen University (probably the first one of its kind in China). The mission of Green Breathing is to promote the public awareness of tobac-

  7. Letters

    Science.gov (United States)

    2001-09-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: M-set as metaphor The abuse of algebra M-set as metaphor 'To see a World in a Grain of Sand And a Heaven in a Wild Flower Hold Infinity in the palm of your hand And Eternity in an hour' William Blake's implied relativity of spatial and temporal scales is intriguing and, given the durability of this worlds-within-worlds concept (he wrote in 1803) in art, literature and science, the blurring of distinctions between the very large and the very small must strike some kind of harmonious chord in the human mind. Could this concept apply to the physical world? To be honest, we cannot be absolutely sure. Most cosmological thinking still retains the usual notions of a finite universe and an absolute size scale extending from smallest to largest objects. In the boundless realm of mathematics, however, the story is quite different. The M-set was discovered by the French mathematician Benoit Mandelbrot in 1980, created by just a few simple lines of computer code that are repeated recursively. As in Blake's poem, this 'world' has no bottom we have an almost palpable archetype for the concept of infinity. I would use the word 'tangible', but one of the defining features of the M-set is that nowhere in the labyrinth can one find a surface smooth enough for a tangent. Upon magnification even surfaces that appeared to be smooth explode with quills and scrolls and lightning bolts and spiral staircases. And there is something more, something truly sublime. Observe a small patch with unlimited magnifying power and, as you observe the M-set on ever-smaller scales, down through literally endless layers of ornate structure, you occasionally come upon a rapidly expanding cortex of dazzling colour with a small black structure at its centre. The black spot appears to be the M-set itself! There is no end to the hierarchy, no bottom-most level, just endless recursive

  8. Letters

    Science.gov (United States)

    2001-05-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Quantum uncertainties Reflections in a plastic box A brief history of quantum physics Correction Grammar and gender Quantum uncertainties Whilst I enjoyed Gesche Pospiech's article ('Uncertainty and complementarity: the heart of quantum physics' 2000 Phys. Educ. 35 393 9) I would like to expand on two comments he makes. Firstly the author claims that QM is linear, and a consequence of this is that any two superimposed states form an admissible third state. This is rather too sweeping, as it is true only for degenerate states. Otherwise quantum mechanics would allow a continuum of energies between states by a simple admixture of levels. The proof of this statement is trivial. For a Hamiltonian H and two orthogonal wavefunctions, ψ1 and ψ2 with energies E1 and E2 then (ψ1 + ψ2) is not an eigenfunction of that Hamiltonian as H(ψ1 + ψ2) = E1ψ1 + E2ψ2 ≠ E(ψ1 + ψ2) for any value of E, unless E1 = E2. Secondly Pospiech states that quantum objects show wave- or particle-like behaviour, depending on the measuring apparatus, and that occasionally experiments (such as Taylor's) reveal both. I would contest the validity of this type of thinking. All experiments on quantum objects reveal both types of behaviour—even ones which simply show straight line motion of photons. What is important, in addition, is our interpretation of the results. It takes an understanding of QED, for example, to see that an experiment which otherwise shows particle behaviour is, in fact, showing quantum behaviour. More contentiously though I would suggest that detection apparatus is incapable of detecting anything other than particles. Wave-like behaviour is revealed only by an analysis of the paths the particle could have taken. In other words, the interference of continuous fields sometimes predicts the same results when the detection is averaged over many events

  9. Letters

    Science.gov (United States)

    2001-07-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Alternative view of education in Zambia Pedantry or compromise Alternative view of education in Zambia I have just read the 'On the Map' report of the International School of Lusaka with very mixed feelings (Physics Education, March 2001). I have recently spent some time in Zambia, in Lusaka, and share Sue Pears' love for the country and the Zambians. The ISL is indeed a good, prestigious school, similar to International Schools in many other countries. But, as in most other developing countries, there is enormous variation between the different types of schooling, and the ISL is at one end of the spectrum. Most schools in Zambia are less favoured. Zambia is a wonderful, beautiful country full of the most friendly and resourceful people I know. It is also a very poor country. It is a country of enormous contrasts and its schools reflect that variation. It has a tiny, affluent 'middle' class of professionals, politicians, businessmen, employees of international businesses and NGOs—nearly all paid from overseas budgets. It has an enormous majority of poor folk, cheerfully living in very basic conditions but sharing their lives in extended families without complaint. The government is virtually bankrupt, and consequently those paid by the government—teachers, police, nurses etc—get a pittance. The wage for a teacher in a typical school is #20 per month (compared to a typical teacher in the UK who gets 100 times more, about #2000 per month). The GNP in Zambia is about 1 per day per person, and this has to pay for all the schools, hospitals, police, and the civic infrastructure that we take so much for granted (the GNP in UK is about 60 per day per person). Consequently most state schools do not have resources; they have a classroom and a teacher but little else. What resources the school has will be paid for by the school fees that every

  10. 9 CFR 316.7 - Marking devices not to be false or misleading; style and size of lettering; approval required.

    Science.gov (United States)

    2010-01-01

    ... figures thereon shall be of such style and type as will make a clear and legible impression. All markings... misleading; style and size of lettering; approval required. 316.7 Section 316.7 Animals and Animal Products... AND THEIR CONTAINERS § 316.7 Marking devices not to be false or misleading; style and size...

  11. Letters

    Science.gov (United States)

    2001-01-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Maths for physics? Help! Fire! Energy and mass Maths for physics? As a maths graduate working as a university research associate I should be well qualified to support my daughter, who has just started AS-level physics, with the maths she needs for the course. There seems to be little integration between the maths and physics departments, so that maths needed for physics has not yet been covered in maths lessons. This is a problem I remember from my own school days, but the shorter timescale and modular nature of the AS and A2 levels means that it is essential that this mismatch of knowledge is resolved now. I would like to know whether physics teachers in the UK have encountered this problem and whether there is a deficiency in the maths syllabus in relation to the requirements of the AS and A2 levels in Physics or whether this is a problem peculiar to my daughter's school. Eleanor Parent of A-level student, Sheffield, UK Help! Fire! Is there a crisis in physics education? Is physics didactics coming to an end? Yes and no. Being a delegate from Norway at the on-going conference Physics on Stage (6-10 November 2000) at CERN in Geneva, I have had the opportunity to discuss this with people from all over Europe. Yes, there is a crisis. (Look at the proceedings for details on this.) I'd like to take a broader look at this situation. Like Hari Seldon in Isaac Asimov's Foundation Trilogy, I believe that there is nothing like a real crisis to get things going... Famous is the quote from the American Patent Office around 1890: 'Everything has been invented that could be invented'. Fortunately, this spurred action. The Michelson and Morley experiment heralded a most exciting period for physics. Just a cosmic blink later we put a person on the Moon. Coming back to the crisis - I am certain that in the near future we will see an interesting development

  12. 76 FR 4601 - Determinations Concerning Need for Error Correction, Partial Approval and Partial Disapproval...

    Science.gov (United States)

    2011-01-26

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 RIN 2060-AQ66 Determinations Concerning Need for Error Correction, Partial Approval... Determination Concerning the Need for Error Correction, Partial Approval and Partial Disapproval, and...

  13. Direct and Indirect Written Corrective Feedback in the Context of Genre-based Instruction on Job Application Letter Writing

    Directory of Open Access Journals (Sweden)

    Mostafa Mirzaii

    2013-10-01

    Full Text Available Despite the fact that a considerable proportion of today’s writing programs operate according to the principles of genre-based instruction, research has not adequately dealt with the teaching of various genres (e.g., job application letters. Nor has research, to date, attempted to address the issue of written corrective feedback in conjunction with genre-based instruction. This study, therefore, aimed to investigate the impact of written corrective feedback in the context of genre-based instruction on job application letters. To this end, 120 Iranian advanced-level EFL learners at Kish Institute of Science and Technology participated in the present study. After administering the TOEFL test, 80 students scoring within ±1 SD of the mean score were randomly assigned to one of two experimental groups?namely, Direct Feedback Group or Indirect Feedback Group. Having sat a writing pretest, the participants received genre-based instruction on how to compose job application letters. Meanwhile, they were supplied with direct or indirect feedback on their writing. Following this instruction, a writing posttest was administered, the results of which showed that direct corrective feedback was more effective than indirect corrective feedback in the context of genre-based instruction on letters of job application.

  14. Letter Report to Address Comments on the Closure Report for Corrective Action Unit 224: Decon Pad and Septic Systems, Nevada Test Site, Nevada, Revision 0, March 2008

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2008-03-17

    The Closure Report (CR) for Corrective Action Unit (CAU) 224, Decon Pad and Septic Systems, was approved by the Nevada Department of Environmental Protection (NDEP) on November 01, 2007. The approval letter contained the following two comments: Comment 1--For 06-05-01, 06-17-04, 06-23-01 provide evidence that the 6 inch VCP pipe originating from building CP-2 is no longer active and sealed to prevent possible future contamination. Comment 2--For the area that includes 06-03-01, provide evidence that active lines are no longer feeding the North and South lagoons and have been sealed to prevent possible future contamination. To address these comments, closure documentation was reviewed, and site visits were conducted to locate and document the areas of concern. Additional fieldwork was conducted in March 2008 to seal the lines and openings described in the two comments. Photographs were taken of the closed drains and lines to document that the NDEP comments were adequately addressed and potential inadvertent discharge to the environment has been eliminated. Investigation and closure documentation was reviewed to identify the locations of potential drains, lines, and other features that could receive and/or transmit liquid. Based on the investigation findings and subsequent closure activities, no openings, distribution boxes, or other features (excluding known floor drains at CP-2) that could receive liquid were found at the CP-2 location (Figure 1), and potential manholes for the north and south sewage lagoons were identified for Corrective Action Site (CAS) 06-03-01 (Figure 2). The distribution box identified in Figure 1 was not located during the investigation and was assumed to have been previously removed.

  15. ASCAD: Approved standard corrective action design-an innovative one-step remedial action plan

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, W.D.; Boyter, N.C.; Martin, D.K. [Westinghouse Savannah River Company, Aiken, SC (United States)

    1994-12-31

    This paper will describe an innovative environmental restoration approach being developed at the Savannah River Site to group sites, define characterization parameters, and match those conditions with standard environmental restoration designs. The package is called the Approved Standardized Corrective Action Design (ASCAD). The purpose of developing this package is to obtain regulator approval of standard technologies and designs for any waste site documented as meeting bounded characterization conditions. For instance, the grouping might be labeled {open_quotes}radioactive basins{close_quotes}. The ASCAD package would contain one design for expected (ABC) conditions defined by characterization. A second design also would be included for DEF conditions should they be encountered. The concept is a next generation of the Streamlined Approach for Environmental Restoration, SAFER where limited characterization and technology selections are conducted in parallel with the processes supporting each other. The impact of ASCAD is to reach remediation faster and lower costs on remedial investigation and design.

  16. 76 FR 25177 - Determinations Concerning Need for Error Correction, Partial Approval and Partial Disapproval...

    Science.gov (United States)

    2011-05-03

    ...-National Ambient Air Quality Standard (NAAQS) pollutants, among them greenhouse gases (GHGs). The partial... Significant Deterioration and Title V Greenhouse Gas Tailoring Rule; Final Rule. 75 FR 31,514 (June 3, 2010... Approval of Prevention of Significant Deterioration Provisions Concerning Greenhouse Gas Emitting...

  17. 75 FR 82365 - Determinations Concerning Need for Error Correction, Partial Approval and Partial Disapproval...

    Science.gov (United States)

    2010-12-30

    .../nursing and 6221, 6231, 6232, 6233, 6239 residential care facilities. Personal and laundry services 8122... Concerning Regulations that Significantly Affect Energy Supply, Distribution, or Use I. National Technology... This action does not impose any new information collection burden. The OMB has previously approved the...

  18. Letter: A method for the chromatic aberration correction of a laser time of-flight mass analyzer.

    Science.gov (United States)

    Sysoeva, Elizaveta A; Sysoev, Alexander A

    2016-01-01

    The new ion-optical system of the laser time-of-flight (TOF) mass spectrometer on the basis of two tandem wedge-shape reflectors has been offered and implemented. A new method of correcting chromatic aberration by the ion energy was proposed that used a wire electrode unit with adjustable potentials. This unit allows one to adjust the local TOF of the ions in a narrow energy range ± (1-2)% within the total ion packet with an energy spread of ± 20%. The method reduces the duration of the ion packets by up to 1.5ns, which enables us to obtain the restriction of resolution at a level not worse than R ~ 10500 for a TOF ~35 µs. The aim of the project is to increase the separation of isobaric ions to improve the limit of detection of the laser TOF-MS for the analysis of high-purity samples.

  19. Allographic agraphia for single letters.

    Science.gov (United States)

    Menichelli, Alina; Machetta, Francesca; Zadini, Antonella; Semenza, Carlo

    2012-01-01

    The case is reported of a patient (PS) who, following acute encephalitis with residual occipito-temporal damage, showed a selective deficit in writing cursive letters in isolation, but no difficulty to write cursive-case words and non-words. Notably, he was able to recognize the same allographs he could not write and to produce both single letters and words in print. In addition to this selective single letter writing difficulty, the patient demonstrated an inability to correctly perform a series of imagery tasks for cursive letters. PS's performance may indicate that single letter production requires explicit imagery. Explicit imagery may not be required, instead, when letters have to be produced in the context of a word: letter production in this case may rely on implicit retrieval of well learned scripts in a procedural way.

  20. Correction

    DEFF Research Database (Denmark)

    Pinkevych, Mykola; Cromer, Deborah; Tolstrup, Martin

    2016-01-01

    [This corrects the article DOI: 10.1371/journal.ppat.1005000.][This corrects the article DOI: 10.1371/journal.ppat.1005740.][This corrects the article DOI: 10.1371/journal.ppat.1005679.].......[This corrects the article DOI: 10.1371/journal.ppat.1005000.][This corrects the article DOI: 10.1371/journal.ppat.1005740.][This corrects the article DOI: 10.1371/journal.ppat.1005679.]....

  1. Corrections

    Science.gov (United States)

    2004-05-01

    1. The first photograph on p12 of News in Physics Educaton January 2004 is of Prof. Paul Black and not Prof. Jonathan Osborne, as stated. 2. The review of Flowlog on p209 of the March 2004 issue wrongly gives the maximum sampling rate of the analogue inputs as 25 kHz (40 ms) instead of 25 kHz (40 µs) and the digital inputs as 100 kHz (10 ms) instead of 100 kHz (10 µs). 3. The letter entitled 'A trial of two energies' by Eric McIldowie on pp212-4 of the March 2004 issue was edited to fit the space available. We regret that a few small errors were made in doing this. Rather than detail these, the interested reader can access the whole of the original letter as a Word file from the link below.

  2. Searching for approval. Tax-exempt hospitals, systems may find some relief through FHLB letters of credit in last week's housing aid bill.

    Science.gov (United States)

    Evans, Melanie

    2008-08-01

    The bill to aid homeowners that Congress passed last week also offered a gift for tax-exempt healthcare borrowers. The law allows the Federal Home Loan Banks to back tax-exempt bonds with letters of credit, thus letting borrowers benefit from those banks' credit strength. But don't expect the floodgates to open. "Banks are preserving their capital for less risky endeavors," says Kelly Arduino, left, of Wipfli.

  3. The Effects of Academic Positive Practice on Cursive Letter Writing.

    Science.gov (United States)

    Mabee, W. Scott

    1988-01-01

    Academic positive practice was used to correct errors of cursive letter writing in three third graders. Following each writing error, students correctly formed each incorrect letter 20 times. Students demonstrated improvement over baseline levels of performance. (Author/DB)

  4. Drugs Approved for Leukemia

    Science.gov (United States)

    This page lists cancer drugs approved by the FDA for use in leukemia. The drug names link to NCI's Cancer Drug Information summaries. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  5. Correction

    CERN Document Server

    2002-01-01

    Tile Calorimeter modules stored at CERN. The larger modules belong to the Barrel, whereas the smaller ones are for the two Extended Barrels. (The article was about the completion of the 64 modules for one of the latter.) The photo on the first page of the Bulletin n°26/2002, from 24 July 2002, illustrating the article «The ATLAS Tile Calorimeter gets into shape» was published with a wrong caption. We would like to apologise for this mistake and so publish it again with the correct caption.

  6. Correction

    CERN Multimedia

    2002-01-01

    The photo on the second page of the Bulletin n°48/2002, from 25 November 2002, illustrating the article «Spanish Visit to CERN» was published with a wrong caption. We would like to apologise for this mistake and so publish it again with the correct caption.   The Spanish delegation, accompanied by Spanish scientists at CERN, also visited the LHC superconducting magnet test hall (photo). From left to right: Felix Rodriguez Mateos of CERN LHC Division, Josep Piqué i Camps, Spanish Minister of Science and Technology, César Dopazo, Director-General of CIEMAT (Spanish Research Centre for Energy, Environment and Technology), Juan Antonio Rubio, ETT Division Leader at CERN, Manuel Aguilar-Benitez, Spanish Delegate to Council, Manuel Delfino, IT Division Leader at CERN, and Gonzalo León, Secretary-General of Scientific Policy to the Minister.

  7. Correction

    Directory of Open Access Journals (Sweden)

    2012-01-01

    Full Text Available Regarding Gorelik, G., & Shackelford, T.K. (2011. Human sexual conflict from molecules to culture. Evolutionary Psychology, 9, 564–587: The authors wish to correct an omission in citation to the existing literature. In the final paragraph on p. 570, we neglected to cite Burch and Gallup (2006 [Burch, R. L., & Gallup, G. G., Jr. (2006. The psychobiology of human semen. In S. M. Platek & T. K. Shackelford (Eds., Female infidelity and paternal uncertainty (pp. 141–172. New York: Cambridge University Press.]. Burch and Gallup (2006 reviewed the relevant literature on FSH and LH discussed in this paragraph, and should have been cited accordingly. In addition, Burch and Gallup (2006 should have been cited as the originators of the hypothesis regarding the role of FSH and LH in the semen of rapists. The authors apologize for this oversight.

  8. Correction

    Directory of Open Access Journals (Sweden)

    2014-01-01

    Full Text Available Regarding Tagler, M. J., and Jeffers, H. M. (2013. Sex differences in attitudes toward partner infidelity. Evolutionary Psychology, 11, 821–832: The authors wish to correct values in the originally published manuscript. Specifically, incorrect 95% confidence intervals around the Cohen's d values were reported on page 826 of the manuscript where we reported the within-sex simple effects for the significant Participant Sex × Infidelity Type interaction (first paragraph, and for attitudes toward partner infidelity (second paragraph. Corrected values are presented in bold below. The authors would like to thank Dr. Bernard Beins at Ithaca College for bringing these errors to our attention. Men rated sexual infidelity significantly more distressing (M = 4.69, SD = 0.74 than they rated emotional infidelity (M = 4.32, SD = 0.92, F(1, 322 = 23.96, p < .001, d = 0.44, 95% CI [0.23, 0.65], but there was little difference between women's ratings of sexual (M = 4.80, SD = 0.48 and emotional infidelity (M = 4.76, SD = 0.57, F(1, 322 = 0.48, p = .29, d = 0.08, 95% CI [−0.10, 0.26]. As expected, men rated sexual infidelity (M = 1.44, SD = 0.70 more negatively than they rated emotional infidelity (M = 2.66, SD = 1.37, F(1, 322 = 120.00, p < .001, d = 1.12, 95% CI [0.85, 1.39]. Although women also rated sexual infidelity (M = 1.40, SD = 0.62 more negatively than they rated emotional infidelity (M = 2.09, SD = 1.10, this difference was not as large and thus in the evolutionary theory supportive direction, F(1, 322 = 72.03, p < .001, d = 0.77, 95% CI [0.60, 0.94].

  9. Correction.

    Science.gov (United States)

    2015-10-01

    In the article by Quintavalle et al (Quintavalle C, Anselmi CV, De Micco F, Roscigno G, Visconti G, Golia B, Focaccio A, Ricciardelli B, Perna E, Papa L, Donnarumma E, Condorelli G, Briguori C. Neutrophil gelatinase–associated lipocalin and contrast-induced acute kidney injury. Circ Cardiovasc Interv. 2015;8:e002673. DOI: 10.1161/CIRCINTERVENTIONS.115.002673.), which published online September 2, 2015, and appears in the September 2015 issue of the journal, a correction was needed. On page 1, the institutional affiliation for Elvira Donnarumma, PhD, “SDN Foundation,” has been changed to read, “IRCCS SDN, Naples, Italy.” The institutional affiliation for Laura Papa, PhD, “Institute for Endocrinology and Experimental Oncology, National Research Council, Naples, Italy,” has been changed to read, “Institute of Genetics and Biomedical Research, Milan Unit, Milan, Italy” and “Humanitas Research Hospital, Rozzano, Italy.” The authors regret this error.

  10. Spatio-temporal properties of letter crowding

    Science.gov (United States)

    Chung, Susana T. L.

    2016-01-01

    Crowding between adjacent letters has been investigated primarily as a spatial effect. The purpose of this study was to investigate the spatio-temporal properties of letter crowding. Specifically, we examined the systematic changes in the degradation effects in letter identification performance when adjacent letters were presented with a temporal asynchrony, as a function of letter separation and between the fovea and the periphery. We measured proportion-correct performance for identifying the middle target letter in strings of three lowercase letters at the fovea and 10° in the inferior visual field, for a range of center-to-center letter separations and a range of stimulus onset asynchronies (SOA) between the target and flanking letters (positive SOAs: target preceded flankers). As expected, the accuracy for identifying the target letters reduces with decreases in letter separation. This crowding effect shows a strong dependency on SOAs, such that crowding is maximal between 0 and ∼100 ms (depending on conditions) and diminishes for larger SOAs (positive or negative). Maximal crowding does not require the target and flanking letters to physically coexist for the entire presentation duration. Most importantly, crowding can be minimized even for closely spaced letters if there is a large temporal asynchrony between the target and flankers. The reliance of letter identification performance on SOAs and how it changes with letter separations imply that the crowding effect can be traded between space and time. Our findings are consistent with the notion that crowding should be considered as a spatio-temporal, and not simply a spatial, effect. PMID:27088895

  11. Spatio-temporal properties of letter crowding.

    Science.gov (United States)

    Chung, Susana T L

    2016-01-01

    Crowding between adjacent letters has been investigated primarily as a spatial effect. The purpose of this study was to investigate the spatio-temporal properties of letter crowding. Specifically, we examined the systematic changes in the degradation effects in letter identification performance when adjacent letters were presented with a temporal asynchrony, as a function of letter separation and between the fovea and the periphery. We measured proportion-correct performance for identifying the middle target letter in strings of three lowercase letters at the fovea and 10° in the inferior visual field, for a range of center-to-center letter separations and a range of stimulus onset asynchronies (SOA) between the target and flanking letters (positive SOAs: target preceded flankers). As expected, the accuracy for identifying the target letters reduces with decreases in letter separation. This crowding effect shows a strong dependency on SOAs, such that crowding is maximal between 0 and ∼100 ms (depending on conditions) and diminishes for larger SOAs (positive or negative). Maximal crowding does not require the target and flanking letters to physically coexist for the entire presentation duration. Most importantly, crowding can be minimized even for closely spaced letters if there is a large temporal asynchrony between the target and flankers. The reliance of letter identification performance on SOAs and how it changes with letter separations imply that the crowding effect can be traded between space and time. Our findings are consistent with the notion that crowding should be considered as a spatio-temporal, and not simply a spatial, effect.

  12. Formation of intonational party of speech in the structure of the correction letter at younger schoolboys with mild expressed general underdevelopment of speech with erased form of dysarthria

    Directory of Open Access Journals (Sweden)

    Zoya Kyrbanova

    2015-05-01

    Full Text Available The problem of reading and writing disorders in children with speech underdevelopment with dizartricheskim component. The methodology of the survey speech capabilities for this category of children. The directions of correctional and developmental work on the formation of intonational party of speech in order to prevent violations of reading and writing.

  13. Drugs Approved for Bladder Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bladder cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  14. Drugs Approved for Breast Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for breast cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  15. Letter to jane addams.

    Science.gov (United States)

    Bloom, M

    1995-06-01

    This letter, written to one of the founding figures in social work, draws parallels between primary prevention at the beginning and the end of the twentieth century. As expected, the letter remains unanswered.

  16. Van: An Open Letter

    Science.gov (United States)

    Tieman, John Samuel

    2011-01-01

    This essay is an open letter from a classroom teacher to a concerned citizen. The letter lists a variety of problems caused largely by standardization and the more corrosive effects of positivism. Many of these problems are unknown to those outside the immediate school setting. While the letter focuses on a specific setting, an inner city school…

  17. The effects of feedback and consequences on transitional cursive letter formation.

    Science.gov (United States)

    Trap, J J; Milner-Davis, P; Joseph, S; Cooper, J O

    1978-01-01

    Twelve first-grade students were employed to analyze the effects of (1) Verbal and Visual Feedback, (2) Verbal and Visual Feedback plus immediate rewriting of trained letters with one or more incorrect letter strokes, and (3) Potential Reinforcement on cursive letter strokes. Students practised both a set of trained and a set of untrained letters during each session. Feedback and reinforcement was administered only for trained letter strokes. The percentage of correct trained letter strokes increased during all conditions. Performance on the untrained but practiced and trained letter strokes followed the same general trend in response pattern. No consistent pattern of generalization was demonstrated with untrained and unpracticed letter strokes.

  18. Heartland Winthrop Approval

    Science.gov (United States)

    This May 19, 2016 letter from EPA approves the petition from Heartland Corn Products regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS program.

  19. Poet Lake Crystal Approval

    Science.gov (United States)

    This September 19, 2016 letter from EPA approves the petition from Poet Biorefining-Lake Crystal, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS

  20. FHR Iowa Falls Approval

    Science.gov (United States)

    This October 22, 2015, letter from EPA approves the petition from Flint Hills Resources, LLC, regarding non-grandfathered ethanol produced through the FHR Iowa Falls Process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the R

  1. THE EFFECTS OF WORD FAMILIARITY AND LETTER STRUCTURE FAMILIARITY ON THE PERCEPTION OF WORDS

    Science.gov (United States)

    An experiment was conducted to test the hypothesis that familiarity of letter structure (as opposed to familiarity of the word ) would facilitate the...perception of the word . The results showed an interaction between letter structure familiarity and work familiarity such that while letter structure...familiarity facilitated correct identification of the letters of the word , letter structure familiarity resulted in inhibiting the perception of

  2. The Business Letter.

    Science.gov (United States)

    Nederland Independent School District, TX.

    GRADES OR AGES: Grades 9-12. SUBJECT MATTER: Business. ORGANIZATION AND PHYSICAL APPEARANCE: This guide, designed for direct student use, indicates the parts of a business letter, a placement guide, and steps for typing letters. Worksheets and illustrations indicate forms of block and indented styles; open, closed, and mixed punctuation; the…

  3. Drugs Approved for Colon and Rectal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for use in colon cancer and rectal cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  4. Letters: Subs, Not Missiles

    National Research Council Canada - National Science Library

    Tsipis, Kosta

    1989-01-01

      In a letter, MIT physicist Kosta Tsipis responds to a column in the August 1988 "Bulletin of the Atomic Scientists" and clarifies his position in regard to the MX and Trident II missile programs...

  5. Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  6. Suicide letters in Singapore.

    Science.gov (United States)

    Chia, Boon-Hock; Chia, Audrey; Tai, Bee-Choo

    2008-01-01

    The contents of suicide letters provide insight into the reasons for suicide and the mental states of victims. Coroner court records of 1,721 Singaporean suicides occurring between 2000 and 2004 were reviewed, 398 (23%) of whom left suicide letters. Letter writers tended to be younger, single, and less likely to have mental or physical illness. A reason for suicide was evident in 58%. Major reasons included school and relationship problems in the young, financial and marital problems in adults and physical illnesses in the elderly. Positive sentiment (care/concern) was expressed in 59%. Negative emotions in 45% of which despondency/agony (60%) was the most common, followed by emptiness (25%), guilt/shame (15%), hopelessness (10%), and anger (3%). The study of these letters suggests that there are combinations of social, psychological and physical factors that influence a person to suicide, all of which are important in the prevention, assessment, and management of suicide.

  7. Letters from Our Readers

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    Since the first publication of Cultural Exchang-China& World in October 1992,we have received a unmber of verykind letters from Chinese and foreign readers giving support andencouagement to this magazine.We would like to take thisopportunity to thank them all and to invite others to write in as well,especially if they have suggestions or criticisms to make.Thefollowing are letters from two of our overseas readers.

  8. Launch of Zoological Letters.

    Science.gov (United States)

    Fukatsu, Takema; Kuratani, Shigeru

    2016-02-01

    A new open-access journal, Zoological Letters, was launched as a sister journal to Zoological Science, in January 2015. The new journal aims at publishing topical papers of high quality from a wide range of basic zoological research fields. This review highlights the notable reviews and research articles that have been published in the first year of Zoological Letters, providing an overview on the current achievements and future directions of the journal.

  9. Temporal processing deficits in letter-by-letter reading.

    Science.gov (United States)

    Ingles, Janet L; Eskes, Gail A

    2007-01-01

    Theories of the cognitive impairment underlying letter-by-letter reading vary widely, including prelexical and lexical level deficits. One prominent prelexical account proposes that the disorder results from difficulty in processing multiple letters simultaneously. We investigated whether this deficit extends to letters presented in rapid temporal succession. A letter-by-letter reader, G.M., was administered a rapid serial visual presentation task that has been used widely to study the temporal processing characteristics of the normal visual system. Comparisons were made to a control group of 6 brain-damaged individuals without reading deficits. Two target letters were embedded at varying temporal positions in a stream of rapidly presented single digits. After each stream, the identities of the two letters were reported. G.M. required an extended period of time after he had processed one letter before he was able to reliably identify a second letter, relative to the controls. In addition, G.M.'s report of the second letter was most impaired when it immediately followed the first letter, a pattern not seen in the controls, indicating that G.M. had difficulty processing the two items together. These data suggest that a letter-by-letter reading strategy may be adopted to help compensate for a deficit in the temporal processing of letters.

  10. 75 FR 62439 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving a...

    Science.gov (United States)

    2010-10-08

    ...-2010-043] Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving..., 2010. I. Introduction On August 6, 2010, the Financial Industry Regulatory Authority, Inc. (``FINRA..., 2010 (``Wiesenberg Letter''); Letter from Manisha Kimmel, Executive Director, Financial...

  11. Immediate error correction process following sleep deprivation

    National Research Council Canada - National Science Library

    HSIEH, SHULAN; CHENG, I‐CHEN; TSAI, LING‐LING

    2007-01-01

    ...) participated in this study. Participants performed a modified letter flanker task and were instructed to make immediate error corrections on detecting performance errors. Event‐related potentials (ERPs...

  12. Drugs Approved for Multiple Myeloma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for multiple myeloma and other plasma cell neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  13. Drugs Approved for Myeloproliferative Neoplasms

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for myeloproliferative neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  14. The Fuzzy Scarlet Letter

    Science.gov (United States)

    Pallas, Aaron M.

    2012-01-01

    Critics of the public release of teacher evaluation scores sometimes liken these ratings to the scarlet letter worn by Hester Prynne in Nathaniel Hawthorne's classic novel. The comparison is apt. But public school teachers who are subjected to public shaming because of their students' test scores can rarely expect the opportunities for redemption…

  15. On The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    徐丹

    2016-01-01

    Reading The Scarlet Letter, one is mostly impressed by the spirit of The Bible the story depicted. The book chiefly discusses sin and how to atone for it. Hester Prynne is the heroine of the fiction. This paper researches her fate to illustrate the influence of The Bible to Hawthorne.

  16. Letter to the Editor

    Directory of Open Access Journals (Sweden)

    Pamela Ann Marshall

    2015-12-01

    Full Text Available A letter to the Editor alerting the ASM education community to the passing of Dr. Joseph P. Caruso, influential colleague and co-author of an article included in the scientific citizenship-themed issue of the Journal of Microbiology & Biology Education (JMBE.

  17. The Scarlet Letter

    NARCIS (Netherlands)

    Hawthorne, Nathaniel

    2005-01-01

    The Scarlet Letter is the story of three New England settlers at odds with the Puritan society in which they live. Roger Chillingworth, an ageing scholar, arrives in New England after two years' separation from his wife Hester to find her on trial for adultery. She refuses to reveal her lover's iden

  18. Lincoln's Letter to Siam.

    Science.gov (United States)

    Alexander, Mary; Childress, Marilyn

    1980-01-01

    Focuses on the problem of the U.S. president receiving gifts from foreign dignitaries. The reproducible letter from President Lincoln to King Rama IV of Siam in which he accepts two gifts and graciously declines proffered elephants serves as center for discussion of the problem. Suggestions for teaching and a crossword puzzle are included. (KC)

  19. Letters in this Issue

    Science.gov (United States)

    1998-01-01

    Reforming the General Chemistry Textbook individual letters by Edward T. Samulski; Stephen J. Hawkes; Stephen J. Fisher; J. Stephen Hartman; A. R. H. Cole; Stanley Pine, Ronald Archer, and Herbert Kaesz; Jimmy Reeves; Robert Hill; and Brock Spencer, C. Bradley Moore and Nedah Rose. Re: article by R. J. Gillespie The author replies

  20. The Scarlet Letter

    NARCIS (Netherlands)

    Hawthorne, Nathaniel

    2005-01-01

    The Scarlet Letter is the story of three New England settlers at odds with the Puritan society in which they live. Roger Chillingworth, an ageing scholar, arrives in New England after two years' separation from his wife Hester to find her on trial for adultery. She refuses to reveal her lover's

  1. The Fuzzy Scarlet Letter

    Science.gov (United States)

    Pallas, Aaron M.

    2012-01-01

    Critics of the public release of teacher evaluation scores sometimes liken these ratings to the scarlet letter worn by Hester Prynne in Nathaniel Hawthorne's classic novel. The comparison is apt. But public school teachers who are subjected to public shaming because of their students' test scores can rarely expect the opportunities for redemption…

  2. President Nixon's Letter of Resignation.

    Science.gov (United States)

    Alexander, Mary; Childress, Marilyn

    1982-01-01

    Contains a primary source document--President Nixon's resignation letter--and suggests teaching strategies for its use with secondary level students. To refresh students' memories of the events surrounding the letter, a selective chronology is also presented. (RM)

  3. Symbolism in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王忠杰

    2007-01-01

    Nathaniel Hawthorne is the greatest American romantic novelist during the nineteenth century. This paper researches the symbolism in his masterpiece The Scarlet Letter from the aspect of the symbolic meaning of the scarlet letter.

  4. Letters to a Young Writer.

    Science.gov (United States)

    Wright, C. D.; Schulman, Grace

    2001-01-01

    Presents two letters to a young writer, modeled on the influential "Letters to a Young Poet" by Rainer Maria Rilke. Notes the first letter situates itself when a young writer first turns toward poetry; and the second addresses the relationship between mentorship and the imagination, questioning the right of any writer to presume to guide the…

  5. Letters to a Young Writer.

    Science.gov (United States)

    Wright, C. D.; Schulman, Grace

    2001-01-01

    Presents two letters to a young writer, modeled on the influential "Letters to a Young Poet" by Rainer Maria Rilke. Notes the first letter situates itself when a young writer first turns toward poetry; and the second addresses the relationship between mentorship and the imagination, questioning the right of any writer to presume to guide the…

  6. A red-letter day !

    CERN Document Server

    2008-01-01

    Today is a red-letter day for the LHC and CERN as a beam of protons has travelled around the LHC ring for the very first time! The start of LHC operation marks the end of a long period in which you have given your all, and this first particle beam circulating in the accelerator now paves the way for discoveries that will open up a whole new field of knowledge. The history of the LHC began in 1984 with a debate on the possible objectives of a future accelerator, based on the state of our knowledge at that time. The CERN Council then approved the single-stage construction of the LHC in 1996, giving the go-ahead for the work that has now reached completion. For the past twelve years, physicists, engineers and technicians from CERN and its associated institutes have been engaged in constructing the three pillars of the LHC: the accelerator (including the upgrade of the existing accelerator chain), the four experiments, and the computing ...

  7. A Letter to Alien

    Institute of Scientific and Technical Information of China (English)

    邱政榜

    2012-01-01

    Dear Alien, 1 am sorry to hear that you have some problems. I hear you argued with your best friend. 1 think you could call him up or go to his home. You could write him a letter. And you could tell him you are sony. Or maybe you could give him a ticket to a ball game. I am sure you will get on well with him again.

  8. The Danish letters

    DEFF Research Database (Denmark)

    Beier, Sofie; Ejlers, Steen

    2011-01-01

    The talk will focus on Danish type designers and their work on Æ (AE), Ø (Oslash) and Å (Aring). These 'anomalies' found in the Danish written language, often causes difficulties for type designers. The counters of Ø/ø sometimes appear overcrowded, the uppercase Æ can result in an uncomfortably o......' attempt to create the optimal variation of these letters, we will give a brief introduction to the Danish typography tradition ranging from the early 20th Century and up until today....

  9. The Danish letters

    DEFF Research Database (Denmark)

    Beier, Sofie; Ejlers, Steen

    2011-01-01

    The talk will focus on Danish type designers and their work on Æ (AE), Ø (Oslash) and Å (Aring). These 'anomalies' found in the Danish written language, often causes difficulties for type designers. The counters of Ø/ø sometimes appear overcrowded, the uppercase Æ can result in an uncomfortably o......' attempt to create the optimal variation of these letters, we will give a brief introduction to the Danish typography tradition ranging from the early 20th Century and up until today....

  10. A comparison of letter and digit processing in letter-by-letter reading.

    Science.gov (United States)

    Ingles, Janet L; Eskes, Gail A

    2008-01-01

    The extent to which letter-by-letter reading results from a specific orthographic deficit, as compared with a nonspecific disturbance in basic visuoperceptual mechanisms, is unclear. The current study directly compared processing of letters and digits in a letter-by-letter reader, G.M., using a rapid serial visual presentation (RSVP) task and a speeded matching task. Comparisons were made to a group of six brain-damaged individuals without reading deficits. In the RSVP task, G.M. had increased difficulty reporting the target identities when they were letters, as compared with digits. Although this general pattern was also evident in the control group, the magnitude of the letter-digit accuracy difference was greater in G.M. Similarly, in the matching task, G.M. was slower to match letters than digits, relative to the control group, although his response times to both item types were increased. These data suggest that letter-by-letter reading, at least in this case, results from a visuoperceptual encoding deficit that particularly affects letters, but also extends to processing of digits to a lesser extent. Results are consistent with the notion that a left occipitotemporal area is specialized for letter processing with greater bilaterality in the visual processing of digits.

  11. Young Children's Letter-Sound Knowledge.

    Science.gov (United States)

    Dodd, Barbara; Carr, Alex

    2003-01-01

    This study with 83 normally developing children (ages 4-6) compared three essential skills in early literacy, letter-sound recognition, letter-sound recall, and letter reproduction. Children performed better in letter-sound recognition than in letter-sound recall and letter reproduction. There were no performance differences due to sex or age.…

  12. Letters to the Editor

    Science.gov (United States)

    1998-03-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Comment on `Magnetic and electric field strengths of high voltage power lines and household appliances' José Luis Giordano Dept. de Ciencia y Tecnología de Materiales y Fluidos, CPSI, Universidad de Zaragoza, Spain Twins paradox S R Carson Norton College, Malton, North Yorkshire, UK On alternative ways of finding the ratio of specific heats of gases Tomas Ficker Physics Department, Technical University of Brno, Czech Republic

  13. A STUDY ON LEGIBILITY OF LETTERING

    Directory of Open Access Journals (Sweden)

    Merve ERSAN,

    2016-04-01

    Full Text Available In the most general sense, lettering is the art of drawing letters, in which the letter forms carry illustrtive features. In this research which is titled "An Analysis on Legibility in Letterings Used in Print Advertisements", letterings used in and specially designed for print ads are analysed and their contribution to the ads are examined. Legibility, which is the fundamental function of writing and typography is examined in the field of lettering that has an illustrative approach. Also, the article puts emphasis on the technique and form’s contribution on content in letterings. Keywords: Lettering, print advertisements, letter design, illustration, legibility.

  14. LEXICAL PHRASEOLOGICAL ANALYSIS OF ENGLISH BUSINESS LETTERS

    Directory of Open Access Journals (Sweden)

    Krivoruchko I. S.

    2015-11-01

    Full Text Available The development of international cooperation has promoted the updating of problems connected with business communication effectiveness. These problems are very crucial, because their solution may predetermine the collaboration success of business partners. The integral part of this success is the efficiency of the exchange of textual information. Nowadays the main information exchange method in modern business relations is business correspondence in English; therefore, its research makes an important contribution to the solution of the pressing problem connected with the achievement of some goals in business. In the article, we analyze both general and specific linguistic features of English business letters, which differ them from texts of other fields of human activity. A special attention is paid to the question of the content and presence degree of lexicological and phraseological units in English business letters. In the end the author comes to the conclusion that business communication is considered effective if it contributes to the mutual understanding of partners with the help of the most optimal means. The analysis of practical material showed that these means could be lexicological and phraseological units. The correct choice of these units helps with the formation of those features of a business letter, which would make it effective

  15. Harvard Education Letter. Volume 26, Number 5, September-October 2010

    Science.gov (United States)

    Walser, Nancy, Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Scenes from the School Turnaround Movement: Passion, Frustration, Mid-Course Corrections Mark Rapid Reforms (Laura Pappano); (2) The Media Savvy Educator:…

  16. Checklist Evaluation for Teaching Business Letters.

    Science.gov (United States)

    Javed, M. Latif

    1981-01-01

    Offers a checklist for use in evaluating business letters written by students. Contends that the checklist can simplify paper checking, objectify grading, help students better prepare their letter assignments, and facilitate their understanding of letter writing principles. (FL)

  17. How to Write a Business Letter

    Institute of Scientific and Technical Information of China (English)

    N·J·斯特克

    2004-01-01

    @@ Generally speaking, there are two kinds of letters, business letters and personal letters. By "business" we do not mean buying, selling, or exchanging goods with people or companies, although it can mean that, but important matters we have to discuss or deal with. A business letter may be a recommendation, a job/college application, an inquiry, an answer, an invitation, a complaint, etc. In other words, all letters that are not "personal"are "business" letters.

  18. Letter to editor

    Directory of Open Access Journals (Sweden)

    Reichmann JP

    2013-01-01

    Full Text Available James P ReichmannSales & Marketing, American HomePatient, Brentwood, TN, USA, I would like to congratulate the authors of the article entitled, "Optimal management of nausea and vomiting of pregnancy" for the comprehensive review of treatments for a frequent complication of pregnancy.1 Although this letter arrives well after publication I think it is important for researchers in the future to have clarification on one seemingly minor but important point. In order to avoid confusion it must be pointed out that in the metoclopramide section the statement "subcutaneous metoclopramide is effective in many women with NVP and HG" is supported by one observational trial on continuous subcutaneous metoclopramide.2 This distinction is very important because that study reported patients were receiving the drug for 26.7 days on average at a cost of $4432 per patient. Unfavorable cost comparisons have been previously published.3 The recommendation that more studied and less expensive alternatives are explored prior to subjecting the patient to this extreme measure seems prudent.4 Perhaps the use of the reference to continuous subcutaneous metoclopramide may have been accidental but the suggestion that "these findings are reassuring, especially for women who experience excessive sleepiness…" implies that women on Diclectin® who report being tired are advanced to continuous subcutaneous metoclopramide seems like a waste of health care resources and a little reckless.1View original paper by Ebrahimi and colleagues.

  19. Commonwealth Agri-Energy, LLC Approval

    Science.gov (United States)

    This December 15, 2016 letter from EPA approves the petition from Commonwealth Agri-Energy, LLC, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the CAA for renewable fuel (D-code 6) RINs under the RFS program.

  20. Montana Advanced Biofuels Great Falls Approval

    Science.gov (United States)

    This November 20, 2015 letter from EPA approves the petition from Montana Advanced Biofuels, LLC, Great Falls facility, regarding ethanol produced through a dry mill process, qualifying under the Clean Air Act for advanced biofuel (D-code 5) and renewable

  1. The Life of the Author in the Letters of “Euripides”

    Directory of Open Access Journals (Sweden)

    Johanna Hanink

    2010-12-01

    Full Text Available The letters spuriously attributed to Euripides engage with and resist the portrait offered by other biographical traditions, sometimes weaving a rival and corrective narrative out of the anecdotes that circulated about him.

  2. Osler and the infected letter

    National Research Council Canada - National Science Library

    Ambrose, Charles T

    2005-01-01

    .... The dissemination of anthrax spores in the US mail in 2001 was a recent example. In 1901, two medical journals reported outbreaks of smallpox presumably introduced by letters contaminated with variola viruses...

  3. Letter from the Friends Chairman

    Science.gov (United States)

    ... Home Current Issue Past Issues Letter from the Friends Chairman Past Issues / Fall 2006 Table of Contents ... FNLM Chairman Paul Rogers converse at a recent Friends function at the National Library of Medicine. Photo ...

  4. The Style of Business Letters

    Institute of Scientific and Technical Information of China (English)

    Li Kai

    2008-01-01

    This study explores the application of Systemic Functional Granunar (SFG) to the analysis of English Business Letters (EBL). With China's opening up to the outside, especially its entrance into WTO, international business is becoming more and more popular. Most of the transactions in international business are discussed in detail through airmail letters, telegrams, telexes, faxes or E-mails.As a world language, English is used widely in the negotiation of international businesses. Writing a piece of effective English Business Letter is of great importance. As a medium between the business partners, EBL affects the interaction and negotiation between them. This article is intended to seek the linguistic characteristics of business letters and prove that the theories of SFG can be used to analyze EBL discourse and they are actually effective.

  5. Readability of standard appointment letters.

    Science.gov (United States)

    Bennett, Daniel M; Gilchrist, Anne

    2010-06-01

    Introduction and aims The first contact a clinical service has with a patient is often an appointment letter and thus it is important that this letter is written in a way which is accessible. One concern is to write in language which is easily able to be read by the majority of recipients. A simple initial way to assess this is by using measures of readability of text.Methods We applied measures to examine the readability of appointment and administrative letters sent to young people by clinicians in the Young People's Department at the Royal Cornhill Hospital in Aberdeen.Results Many letters were unlikely to be understood by our youngest patients. We revised the letters to meet an agreed standard of readability, and agreed their routine use within the team. All letters were significantly improved on standard measures of readability and were preferred by patients.Conclusions The methods used are feasible, easily available and may be helpful to clinicians working in other specialties to improve the level of readability of written communication. This will help patients and families in their first contact with any clinical service.

  6. Lapse resistance in the verbal letter reporting task.

    Science.gov (United States)

    Arditi, Aries

    2006-04-01

    Lapses, or misreporting errors, can affect accuracy of threshold measurements. Assumptions about lapse rate, especially in untrained observers, have consequently guided the design of at least one clinical psychophysical test. Lapse rate was assessed using a verbal letter identification paradigm like that used in visual acuity and letter contrast sensitivity testing. Subjects occasionally made slip-of-the tongue errors but spontaneously corrected them. Lapse rate (excluding such errors) was 0-3 errors per 1,536 (average rate of 0.0005). In this common clinical paradigm, in which observers set their reporting pace, and where opportunity to amend responses is available, lapse rate is negligible.

  7. Letter Writing: A Tool for Counselor Educators

    Science.gov (United States)

    Hoffman, Rachel M.

    2008-01-01

    Letter writing is an integral component of narrative therapy practice. In addition to the benefits of letter writing in counseling practice, letter writing may hold interesting possibilities for use in counselor education. This article provides a brief review of the benefits of letter writing in counseling practice and discusses the potential use…

  8. Essay: Physical Review Letters; Sam Goudsmit's Vision.

    Science.gov (United States)

    Adair, Robert K

    2008-01-18

    Sam Goudsmit implemented his vision of converting the Letters section of Physical Review into a distinct journal fifty years ago. Physical Review Letters was designed to publish "only papers that really deserve rapid communication." The new journal became so successful with physicists throughout the world that Physical Review Letters now publishes 3500 Letters per year.

  9. Unit 2: Application Letters & The Job Interview

    OpenAIRE

    Aleson Carbonell, Marian

    2007-01-01

    Unit 2a_ Letters of Application and the CV: Reading the employment section. Unit 2b_Letters of Application and the CV:Writing Letters and the Job Hunting Process. Unit 2c_ Letters of Application and the CV: The Job Interview.

  10. Effects of Letter-Identification Training on Letter Naming in Prereading Children

    Science.gov (United States)

    Hayashi, Yusuke; Schmidt, Anna C.; Saunders, Kathryn J.

    2013-01-01

    Three prereading children who named 0 to 3 of 20 targeted letters were taught to select the 20 printed letters when they heard spoken letter names. For all participants, letter-identification training resulted in naming for the majority of letters.

  11. Symbolism in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    苑文良

    2005-01-01

    A famous writer in American Renaissance, Nathaniel Hawthorne was deeply influenced by three thoughts, Puritanism consciousness, transcendental philosophy and transcendentalism .Novel The Scarlet Letter is Hawthorne's most remarkable masterpiece. It thoroughly response to people's spirit wreck of Puritanism and unbridled pursuit for happy life. Meanwhile, The Scarlet Letter also makes Nathanael Hawthorne known all around the world. Hawthorne uses the symbolism so skilfful that it enhances the artistic effects of his work greatly. This paper researches the symbolism in this novel from the following aspects: the changing symbolic meaning of the scarlet letter, the names of the major characters and many objects that are described in the novel to make the symbolism clear to the readers.

  12. Symbolism in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    苑文良

    2005-01-01

    A famous writer in American Renaissance, Nathaniel Hawthorne was deeply influenced by three thoughts, Puritanism consciousness, transcendental philosophy and transcendentalism .Novel The Scarlet Letter is Hawthorne's most remarkable masterpiece. It thoroughly response to people's spirit wreck of Puritanism and unbridled pursuit for happy life. Meanwhile, The Scarlet Letter also makes Nathaniel Hawthorne known all around the world. Hawthorne uses the symbolism so skillful that it enhances the artistic effects of his work greatly. This paper researches the symbolism in this novel from the following aspects: the changing symbolic meaning of the scarlet letter, the names of the major characters and many objects that are described in the novel to make the symbolism clear to the readers.

  13. THE POWER OF LOWERCASE LETTERS IN READING

    Directory of Open Access Journals (Sweden)

    Firdevs GÜNEŞ

    2012-06-01

    Full Text Available Today, the most superior way of obtaining knowledge is reading. Reading gives direction to the individual's language, cognitive, social skills and future. For this reason, great importance is given to the teaching of reading. The teaching of reading is carried out based on two basic skills including word recognition and comprehension. In the word recognition process, appearance of the letters the shapes of the wordswritten in uppercase or lowercase letters are effective. Brain research reveal that the words written in small letters more quickly recognized and understood. Based on the recognition of words written in capital letters, small letters become stronger and they are recognised easier than the capital letters. For this reason, a text written in small letter is read more quickly than in capital letters. In addition, text in lowercase letters makes to examine all the details of the text, in-depth awareness and understanding. Small letters are in the process of visual recognition, attention, and remember the rule affects reading, seeing, understanding, and accelerates the configuration tasks in mind. This situation makes the use of lowercase letters in advertising. The advertising in small letters and logos were more easily recognized and remembered. Therefore, in order to increase strength of association big companies and brands, are used lowercase letters. In reading activities taking these results into well known and necessary precautions should be taken about lowercase letters.

  14. Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Triana, Michel; Ternier, Stefaan; Hartkopf, Kathleen; Stieger, Lina; Schroeder, Hanna; Sopka, Sasa; Drachsler, Hendrik; Maher, Bridget; Henn, Patrick; Orrego, Carola; Marcus, Specht

    2014-01-01

    The electronic discharge letter mobile app takes advantage of Near Field Communication (NFC) within the PATIENT project and a related post-doc study. NFC enabled phones to read passive RFID tags, but can also use this short-range wireless technology to exchange (small) messages. NFC in that sense co

  15. Curriculum Vitae and Related Letters.

    Science.gov (United States)

    Peterson, Sharyl Bender

    This booklet, which was developed by a college career center, explains the purpose of and procedures for writing curriculum vitae (CV) and related letters. The following topics are covered: when a CV is appropriate, points to consider when writing a CV, items usually included, possible sections to include in a CV, and steps in writing cover…

  16. Letter to a Young Writer.

    Science.gov (United States)

    Hirsch, Edward

    2002-01-01

    Describes, in the form of a letter to a young writer, how the author celebrates the pendulous life of the poet: from arrogance to uncertainty, from misstep to breakthrough. Emphasizes the sustaining force of reading and the need to be initiated into one's own work by the work of others. (SG)

  17. "The Scarlet Letter". [Lesson Plan].

    Science.gov (United States)

    Discovery Communications, Inc., Bethesda, MD.

    Based on Nathaniel Hawthorne's novel "The Scarlet Letter," this lesson plan presents activities designed to help students understand that the ending of a novel does not resolve all of the questions that may occur to readers; and that readers may imagine characters living out their lives beyond the ending the author gave to a novel. The main…

  18. 22 CFR 124.12 - Required information in letters of transmittal.

    Science.gov (United States)

    2010-04-01

    ... AGREEMENTS, OFF-SHORE PROCUREMENT AND OTHER DEFENSE SERVICES § 124.12 Required information in letters of transmittal. (a) An application for the approval of a manufacturing license or technical assistance agreement... scope of the agreement. (3) A statement identifying the U.S. Government contract under which the...

  19. Effects of stimulus duration and inter-letter spacing on letter-in-string identification.

    Science.gov (United States)

    Marzouki, Yousri; Grainger, Jonathan

    2014-05-01

    Effects of stimulus duration and inter-letter spacing were studied in a letter-in-string identification paradigm. Participants were shown strings of 5 random consonants (e.g., PGKDM) centered on fixation and were asked to identify the letter that had appeared at a post-cued location. Stimulus duration was manipulated in Experiment 1 (13 ms-91 ms), and inter-letter spacing manipulated in Experiment 2 (for a fixed stimulus duration of 26 ms). We contrasted performance to outer-letters (positions 1 and 5) with non-central inner letters (positions 2 and 4), the first-letter (position 1) with the final letter (position 5), and the central-letter (position 3) with the other inner letters (positions 2 and 4). The outer-letter advantage and the first-letter advantage were present throughout the entire range of exposure durations, whereas the central-letter advantage increased with longer exposures. On the other hand, increased spacing reduced both the outer-letter advantage and the first-letter advantage, whereas it led to a greater central-letter advantage. Changes in acuity and crowding as a function of stimulus exposure and inter-letter spacing, can account for this pattern of results.

  20. Letter to President [Lostwood National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Lostwood Wilderness area. The letter discusses the...

  1. When your words count: a discriminative model to predict approval of referrals

    Directory of Open Access Journals (Sweden)

    Adol Esquivel

    2009-12-01

    Conclusions Three iterations of the model correctly predicted at least 75% of the approved referrals in the validation set. A correct prediction of whether or not a referral will be approved can be made in three out of four cases.

  2. The Presentation of Courtesy in Business Letter

    Institute of Scientific and Technical Information of China (English)

    刘文君

    2013-01-01

    Nowadays the tendency of economic globalization in the world brings about increasingly closer international trade cooperation. The business letter has been an important communicative tool in the international trade. A polite business letter could promote the trade and help achieve the business cooperation. Therefore the presentation of courtesy in the business letter is of great significance. This paper presents a study of the courtesy in the business letter from the lexical aspect.

  3. Letter to Editor

    Directory of Open Access Journals (Sweden)

    Bijan Sadrizadeh

    2009-12-01

    previous pandemics. We are also see­ing stories which are simply a manipulation. Some of the issues, however, are also extremely difficult to explain. The spread has been very fast. Most people develop self limited illness. However, there is still much concern because those who die are more likely to die from an unusually rapid and severe respiratory failure, thought to be initiated by pri­mary viral pneumonia, rather than the causes usually seen with seasonal flu and those dying are also much younger. Finally, many countries have been able to function during the pandemic. However, some countries and their health systems have undergone extreme stress. Finally, we need to know what is going on now but must be prepared for the future- which could be a less severe disease, the same thing, or a more severe disease.                                                                                                                               Putting this all together in a way the regular person can understand has not been easy, so typically, a re­porter stresses one or another aspect and we often see imbalanced stories.          anyway I believe the answer is not to try and correct all of these stories one by one-an endless task-but to further develop our communications and information strategy so that WHO is more consistently put­ting out accurate information on a regular basis. We will step up.                                                                                                                                               It is very good to hear from you and best regards.   Keiji   The interesting point in the above exchange of emails is the fact that somebody in WHO has the respon

  4. 7 CFR 3560.709 - Demand letter.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Demand letter. 3560.709 Section 3560.709 Agriculture... DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.709 Demand letter. (a) If a... repayment schedule, the Agency will send the borrower a demand letter specifying: (1) The amount of...

  5. 31 CFR 29.511 - Demand letters.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Demand letters. 29.511 Section 29.511... Overpayments § 29.511 Demand letters. Except as provided in § 29.516(e), before starting collection action to recover an overpayment, the Benefits Administrator must send a demand letter that informs the debtor in...

  6. Beyond Zebra: Preschoolers' Knowledge about Letters.

    Science.gov (United States)

    Treiman, Rebecca; Richmond-Welty, E. Daylene; Tincoff, Ruth

    1997-01-01

    Argues that an important type of child knowledge about letters is knowledge of the phonological structure of the letters' names in English. Concludes that learning the alphabet forms the basis for generalizations about the structure of letter names. (22 references) (Author/CK)

  7. Letter names and phonological awareness help children to learn letter-sound relations.

    Science.gov (United States)

    Cardoso-Martins, Cláudia; Mesquita, Tereza Cristina Lara; Ehri, Linnea

    2011-05-01

    Two experimental training studies with Portuguese-speaking preschoolers in Brazil were conducted to investigate whether children benefit from letter name knowledge and phonological awareness in learning letter-sound relations. In Experiment 1, two groups of children were compared. The experimental group was taught the names of letters whose sounds occur either at the beginning (e.g., the letter /be/) or in the middle (e.g., the letter /'eli/) of the letter name. The control group was taught the shapes of the letters but not their names. Then both groups were taught the sounds of the letters. Results showed an advantage for the experimental group, but only for beginning-sound letters. Experiment 2 investigated whether training in phonological awareness could boost the learning of letter sounds, particularly middle-sound letters. In addition to learning the names of beginning- and middle-sound letters, children in the experimental group were taught to categorize words according to rhyme and alliteration, whereas controls were taught to categorize the same words semantically. All children were then taught the sounds of the letters. Results showed that children who were given phonological awareness training found it easier to learn letter sounds than controls. This was true for both types of letters, but especially for middle-sound letters. Copyright © 2011. Published by Elsevier Inc.

  8. Michelangelo, a Tireless Letter Writer

    Directory of Open Access Journals (Sweden)

    Adelin Charles Fiorato

    2014-04-01

    Full Text Available A titan of artistic creation, the sculptor-painter-architect Michelangelo was also a tireless letter writer. Five hundred and eighteen of his letters have reached us, stretching from his youth to the eve of his death, but we know that many others have been lost. Written in a kind of familiar Florentine and in a style of minimalist ‘realism’ – which does not prevent the presence of either impetuous polemical flights or pages of literary indulgence – these letters deal mainly with everyday subjects: day-by-day relationships, either endearing or resentful, with his relatives, financial or property matters and, above all, the marriage problems which concerned his nephew Leonardo, the sole heir of the family. But one also discovers in them the artist’s warm feelings of friendship and love, his poetic and aesthetic exchanges, his relationships, often conflictual, with his fellow-artists and patrons as well as his reflections on old age and death. All in all, these letters represent a documentary chronicle of a Florentine bourgeois family and the technical hassle of an entrepreneur’s activity. If, on the one hand, the Carteggio does not shed light either on Michelangelo’s conception of art or the way in which he realized his works, on the other it illustrates certain latent aspects of his projects, as well as of his personality, which was at the same time melancholy and aggressive, surprisingly whole and manifold. This luxuriant correspondence presents, so to speak, a ‘genetic’ interest, since it reveals the hidden face of the brilliant conceiver and creator, of the artist and entrepreneur struggling with the obstacles whose overcoming makes creation possible. 

  9. A bread-and-butter letter

    Institute of Scientific and Technical Information of China (English)

    王道庚

    2007-01-01

    @@ letter作"信"讲是很常用的词,私人信件是personal letter,业务信件叫做business letter,祝贺信是letter of congratulation,邀请信是letter of invitation 等等.还有一种信是a bread-and-butter letter,你知道是什么信吗?我们知道bread and butter是涂有黄油的面包,那么,a bread-and-butter letter就是"黄油面包信"吧?非也.

  10. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Tobacco Problem Your recent cover story 'Tobacco Dilemma" (Issue No.9, March 2, 2006) should not be a dilemma at all. The Chinese Government should just come down very hard on cigarette smoking. It does not make sense to let tobacco smoking proliferate because it enriches government coffers through heftv taxes. Tobacco smokine is an

  11. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Despicable Acts Images of children starving to death are always disturbing.After reading a report about how food aid is being stolen and then sold on the market in Somalia I was saddened,sickened and outraged at the same time.A news report from Associated Press said that the food reaches the hungry people in the refugee camps and is then being removed from them with threats of violence and sold for profit.What kind of people are these that we share the planet with.What would make someone

  12. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Dear Editor, Ref.To our tele talk to day,I have the honour to write you as you claimed that"Rarely do journalist challenge the Dalai Lama". Dalai Lama is an hypocrite who used to systematically fool people and his principle of peace are too bogus,he must be stopped in the frame work of peace as his fol-lowers are sluggish and kept themself burried under ignorance.

  13. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    EkooniBaje It brings me much joy to write about your article on Lagos(February issue).I felt obliged to use this opportunity to show to China and the rest of the world that there is a home for them in Lagos."Eko o ni Baje" is a popular local slogan in Lagos,Nigeria which simply means "Lagos will not spoil." Recently,the Nigerian community in Beijing and across China together with the Chinese Government celebrated 40 years of bilateral trade relations with China.This is to

  14. Letters

    Science.gov (United States)

    2000-04-01

    Coulombic Models in Chemical Bonding by Lawrence J. Sacks and by Derek W. Smith Re: articles by R. J. Gillespie and by D. W. Smith D. W. Smith replies Capsaicin Hazard by Paul E. Vorndam Re: article by J. D. Batchelor and B. T. Jones B. T. Jones reply Editor's Note: Hazards Re: JCE 1999, 76, 240 and JCE 2000, 77, 266.

  15. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Give Peace a Chance The African Union(AU) has put forward a four-point formula to end the civil war in Libya.These points are:an immediate ceasefire by all military actions;continued humanitarian aid to those in need;protection of foreigners,including African expatriates living in Libya;and creation of a necessary political reforms agenda to eliminate the causes of the present crisis.This is all a clear indication that the AU is

  16. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Veggie Dream I was interested to read your articles about vegetarianism(January issue) and how it is catching on in China.I always imagined China to be a meat eating country before. Being vegetarian is very misunderstood by many people.I am a vegetarian and it has taught me to be very tolerant.If I go to any banquet,dinner,buffet,cocktail party,or any other event where food is served,I have learned to always try and eat beforehand or at least carry some of my own snacks.Vegetarians are rarely,if ever,catered for at social events,apart from the odd carrot or celery stick,tucked away in between the moun-

  17. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Female Farmers Zambian female farming groups are very happy to hear the news that the government has launched a $500,000 Sustainable Livelihood and Women Empowerment Project. Poor women farmer groups will now at least have some opportunity of getting financial help as well as help with new technology.We women farmers will also get help with training and livestock resources.The project is said to support 1,900 households and is in part of the process toward meeting the millennium goals.

  18. Letters

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    My name is Tom R. Chambers. I have been teaching English in Sheng Da College (near Zhengzhou) for two years,and faithfully reading your publication for over a year. I am also a documentary photographer, and I wonder if you'd be interested in publishing my experiences in China. I've created a Sheng Da College/China Travels website, which I feel is aninteresting approach to a travelogue,

  19. Letters

    Science.gov (United States)

    1999-04-01

    Winter's Entertainment by Terry L. Helser Ammonia-Air Mixtures Can Be Explosive by David Tudela Re: article by S. Toby The author replies Teaching Statistical Methods by Ken Muranaka Re: article by K. Thomasson, S. Lofthus-Merschman, M. Humbert, and N. Kulevsky The author K. A. Thomasson replies Properties of Zeolite A Obtained from Powdered Laundry Detergent by Pamela J. Davis, Herman van Bekkum, and Eric N. Coker Re: article by D. A. Lindquist and A. L. Smoot The author D. A. Lindquist replies Photon-Initiated Hydrogen-Chlorine Reaction by Richard W. Schwenz and Lynn Geiger Re: article by L. M. Egolf and J. T. Keiser (J. Chem. Educ. 1993, 70, A208) Precision and Accuracy in Measurements by Volker B. E. Thomsen Re: article by R. Treptow The author replies

  20. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Waste Not,Want Not I enjoy reading your magazine and was moved by your story about the massive famine in the Horn of Africa in your September issue.Last week I attended a banquet for an outgoing official at a popular restaurant in Beijing.We had many different dishes and after we had finished I noticed how much food remained uneaten on the table.After having read your story I thought about how so much is wasted in one place and so much needed in another.How does that happen? I felt guilty and wanted to do something to help at that moment. I think as people sharing the same planet we must be aware of what goes on

  1. LETTERS

    Institute of Scientific and Technical Information of China (English)

    Deqyi

    2008-01-01

    Dear degyi, Number two arrived-it looks good-it looks normal Tibet again after all that NEWS NEWS NEWS we had last week about Lhasa.I haven't read it yet-just turning the pages to get first impression. I like the clear printing pictures of mountains Tibetan areas,Tibetan horse,Tibetan sheep grazing at foot of mountains,Tibetan girls in out of this world Tibetan dresses,Tibetan town under Heaven, Kyirong men,rope bridge with streamers.Tibetan history engraved in rock; I like beer-but I don't like beer tac...

  2. Letter: supplementary pyridoxine given to women using oral contraceptives.

    Science.gov (United States)

    Winston, F

    1975-07-15

    This letter is a response to an article describing the efficacy of administering large doses of tryptophan to depressive patients taking oral contraceptives. This letter-writer argues that the salient action of mood elevation is a result of the supplemental pyridoxine (vitamin B) which ameliorates the deficiency induced by oral contraceptive use that leads to depression resulting from inhibition of synthesis of biogenic amines in the central nervous system. Instead of large doses of tryptophan, which may cause dangerous accumulations of possibly carcinogenic and diabetogenic metabolites when therapy for depression is indicated, pyridoxine should be administered together with the tryptophan; the tryptophan should be discontinued once the deficiency is corrected, although the vitamin therapy should continue throughout oral contraceptive use.

  3. Drugs Approved for Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for ovarian cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  4. [Lake Mason and Soo Line Marsh project design approval

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter is the approval from the U.S. Fish and Wildlife Service of the designs created by Ducks Unlimited, Inc. for the Lake Mason and Soo Line Marsh National...

  5. Pragmatic Functions of Hedges in Business Letters

    Institute of Scientific and Technical Information of China (English)

    刘璐璐

    2013-01-01

    The aim of the present research to explore the hedges used English business letters. Several samples have been chosen to make qualitative study in order to achieve the goal of answering the following question: what are the pragmatic functions of hedges being used in business letters? After analyzing the samples, the conclusion could be came that the employment of hedges in business letters has three pragmatic functions—giving the right amount of information, being polite and self-production.

  6. Secret letters cast light on Copenhagen

    Energy Technology Data Exchange (ETDEWEB)

    Durrani, Matin

    2001-11-01

    Letters by Niels Bohr that have been kept secret since his death could explain the mystery of why Werner Heisenberg visited him in Copenhagen in 1941. When the author Michael Frayn spent two years writing Copenhagen, he had no idea how successful the play would become. He doubted that audiences would sit through a historical drama about a war-time meeting between Werner Heisenberg - head of Germany's nuclear programme - and his old mentor Niels Bohr in the Nazi-occupied Danish capital in 1941. But Frayn's efforts paid off. Audiences and critics alike have thrilled at the way the award-winning play probes the historical uncertainty that surrounds the encounter. Was Heisenberg fishing for information about the Allies' atomic plans - or was he trying to recruit Bohr for Germany's bomb programme? Did Heisenberg want to suggest that the Germans were close to finishing a bomb so that the Allies would make peace with Hitler? Maybe he was simply seeking approval from Bohr for his own atomic work. There is also a moral debate: did Heisenberg know how to build a bomb, but decided not to - or did he want to build one, but got his calculations wrong? Unfortunately, no-one was there to record or observe the encounter and we cannot know for sure what was said or implied between the two men. All we do know is that the pair dined together and took a short walk - and that the incident damaged Bohr and Heisenberg's friendship forever. To piece together what happened, historians of science have had to rely on Heisenberg's post-war recollections - which have been ambiguous and contradictory - along with scraps of evidence from secondary sources. (U.K.)

  7. Resource Letter: GW-1: Global warming

    Science.gov (United States)

    Firor, John W.

    1994-06-01

    This Resource Letter provides a guide to the literature on the possibility of a human-induced climate change—a global warming. Journal articles and books are cited for the following topics: the Greenhouse Effect, sources of infrared-trapping gases, climate models and their uncertainties, verification of climate models, past climate changes, and economics, ethics, and politics of policy responses to climate change. [The letter E after an item indicates elementary level or material of general interest to persons becoming informed in the field. The letter I, for intermediate level, indicates material of somewhat more specialized nature, and the letter A indicates rather specialized or advanced material.

  8. [Darwin in the Republic of Letters].

    Science.gov (United States)

    Bertani, Stefano

    2013-01-01

    For those accustomed to thinking that the modern cultural dimension arose under the banner of a clash between the so-called "two cultures," the figure of Darwin the "humanist" could reserve numerous surprises. It was above all the well-known paleontologist S.J. Gould who pointed them out. He went so far as to track down, in the Italian cultural roots from Saint Francis to Galileo, an element of continuity between his own Darwinism and our literary tradition that passes through the writing of the masterpieces of the nineteenth-century natural sciences. On the basis of a similar, and also audacious, rereading of the cultural history, the essay proposes to indicate some possible developments of the new dialogue undertaken, beginning with the insertion of the scientist Darwin in the European horizon of the Republic of Letters. There are then indicated some historical-cultural categories that would merit reconsideration: the new figure of intellectual of the twenty-first century, the idea of a science immersed in the historical contingency and in the concrete pleasure of the subject that knows, the role of "sweetness" and of "wonder" also in the most rigorous study, and lastly the need of an in-depth knowledge of the Darwinian writing, not as a curiosity for the educational trend of the era of positivism, but as an indispensable epistemological requisite for a correct understanding of its science.

  9. Effect of orthographic processes on letter-identity and letter-position encoding in dyslexic children

    Directory of Open Access Journals (Sweden)

    Caroline eReilhac

    2012-05-01

    Full Text Available The ability to identify letters and encode their position is a crucial step of the word recognition process. However and despite their word identification problem, the ability of dyslexic children to encode letter-identity and letter-position within strings was not systematically investigated. This study aimed at filling this gap and further explored how letter identity and letter position encoding is modulated by letter context in developmental dyslexia. For this purpose, a letter-string comparison task was administered to French dyslexic children and two chronological-age (CA and reading-age (RA-matched control groups. Children had to judge whether two successively and briefly presented 4-letter-strings were identical or different. Letter-position and letter-identity were manipulated through the transposition (e.g., RTGM vs. RMGT or substitution of two letters (e.g., TSHF vs. TGHD. Non-words, pseudo-words and words were used as stimuli to investigate sub-lexical and lexical effects on letter encoding. Dyslexic children showed both substitution and transposition detection problems relative to CA controls. A substitution advantage over transpositions was only found for words in dyslexic children whereas it extended to pseudo-words in RA controls and to all type of items in CA controls. Letters were better identified in the dyslexic group when belonging to orthographically familiar strings. Letter position encoding was very impaired in dyslexic children who did not show any word context effect in contrast to CA controls. Overall, the current findings point to a strong letter identity and letter position encoding disorder in developmental dyslexia.

  10. Letters from the Future: Suggestions for Using Letter Writing as a School Counselling Intervention

    Science.gov (United States)

    Kress, Victoria E.; Hinkle, Michelle Gimenez; Protivnak, Jake J.

    2011-01-01

    This article presents a school counselling intervention that utilises letters written from the future. Few peer-reviewed articles have addressed the use of letter writing in a school counselling context, and none have focused on the use of letters from the future as a means of school counsellor intervention. The authors present a theoretical…

  11. Disentangling the Developmental Trajectories of Letter Position and Letter Identity Coding Using Masked Priming

    Science.gov (United States)

    Kezilas, Yvette; McKague, Meredith; Kohnen, Saskia; Badcock, Nicholas A.; Castles, Anne

    2017-01-01

    Masked transposed-letter (TL) priming effects have been used to index letter position processing over the course of reading development. Whereas some studies have reported an increase in TL priming over development, others have reported a decrease. These findings have led to the development of 2 somewhat contradictory accounts of letter position…

  12. Letter-Name Letter-Sound and Phonological Awareness: Evidence from Greek-Speaking Kindergarten Children

    Science.gov (United States)

    Manolitsis, George; Tafa, Eufimia

    2011-01-01

    The purpose of this study was to examine longitudinally the development of letter-sound and letter-name knowledge and their relation to each other and to various aspects of phonological awareness in a sample of Greek kindergarten children who did not know how to read. One hundred twenty children aged 58-69 months were assessed on letter-sound and…

  13. Disentangling the Developmental Trajectories of Letter Position and Letter Identity Coding Using Masked Priming

    Science.gov (United States)

    Kezilas, Yvette; McKague, Meredith; Kohnen, Saskia; Badcock, Nicholas A.; Castles, Anne

    2017-01-01

    Masked transposed-letter (TL) priming effects have been used to index letter position processing over the course of reading development. Whereas some studies have reported an increase in TL priming over development, others have reported a decrease. These findings have led to the development of 2 somewhat contradictory accounts of letter position…

  14. Drugs Approved for Melanoma

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Melanoma This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Melanoma Aldesleukin Cobimetinib Cotellic (Cobimetinib) Dabrafenib Dacarbazine DTIC-Dome ( ...

  15. From Numbers to Letters: Feedback Regularization in Visual Word Recognition

    Science.gov (United States)

    Molinaro, Nicola; Dunabeitia, Jon Andoni; Marin-Gutierrez, Alejandro; Carreiras, Manuel

    2010-01-01

    Word reading in alphabetic languages involves letter identification, independently of the format in which these letters are written. This process of letter "regularization" is sensitive to word context, leading to the recognition of a word even when numbers that resemble letters are inserted among other real letters (e.g., M4TERI4L). The present…

  16. TEACHERS' VIEWS ON CURSIVE LETTERS FONTS

    Directory of Open Access Journals (Sweden)

    Erol DURAN

    2011-06-01

    Full Text Available This study is subject to forms of writing letters in cursive font. Research is descriptive screening model. Researcher, 227 primary school teachers with the first writing in cursive writing teaching to previously made in the province and district in Ankara, " Cursive Letters Shape Writing Assessment" named semi-structure interview form applied. Teachers in this survey, the shape of the letter, if appropriate, the letter an "appropriate" to write, did not find the appropriate letter in the shape of the new propositions were asked to spell. The data was descriptively analysed and interpreted after then. 16% of teachers participating in the research, the teaching of cursive writing not find a significant and steep wants to return to perpendicular to the basic text writing. 12% of the teachers, the cursive letters stated that the whole appropriate shape patterns grows. Participated in the study with other teachers, most of the letters in "appropriate" expression while falling, "b, d, f, k, r, s, ş, v, z, B, D, L, T, Z" the letters and shape patterns indicate that it should be changed new faces in this case suggested shape.

  17. Statistical Learning, Letter Reversals, and Reading

    Science.gov (United States)

    Treiman, Rebecca; Gordon, Jessica; Boada, Richard; Peterson, Robin L.; Pennington, Bruce F.

    2014-01-01

    Reversal errors play a prominent role in theories of reading disability. We examined reversal errors in the writing of letters by 5- to 6-year-old children. Of the 130 children, 92 had a history of difficulty in producing speech sounds, a risk factor for reading problems. Children were more likely to reverse letter forms that face left, such as…

  18. Essay: the origin of physical review letters.

    Science.gov (United States)

    Trigg, George L

    2008-11-21

    When Sam Goudsmit, then Editor of Physical Review, decided to publish the Letters separately, he asked me to become Assistant Editor of the new journal. I wound up staying at PRL for a quarter of a century. I describe some of the new techniques we developed to speed up review and production so that Letters could be quickly published.

  19. 24 CFR 241.1010 - Feasibility letter.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Feasibility letter. 241.1010 Section 241.1010 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request...

  20. Letters to the Editor: What Is Stuttering?

    Science.gov (United States)

    Yairi, Ehud; Watkins, Ruth; Ambrose, Nicoline; Paden, Elaine

    2001-01-01

    The authors of a research report (1999) on the diagnosis of stuttering in young children respond to a critical letter by questioning the accuracy, validity, credibility, and internal consistency of the letter writer's criticisms. The reply goes on to clarify the evaluation of stuttering-like disfluencies and single-syllable word repetitions in…

  1. Writing Back and Forth: Class Letters.

    Science.gov (United States)

    Fulwiler, Toby

    1997-01-01

    Recommends that college teachers and their students exchange weekly letters, in either paper or electronic form, as a familiar and friendly means of communication. The method increases dialog, suggests rethinking, and encourages rewriting while keeping the stakes low. Students respond well to the assignment. Samples of student letters and comments…

  2. Feminist Criticism in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    魏福林; 何志燕

    2007-01-01

    The Scarlet Letter written by Nathaniel Hawthorne is a great book. Through feminist criticism we can get how The Scarlet Letter may be read as dramatizing Hester Prynne's spiritual and physical struggle to survive as an individual in a society whose values authorize the privileged power of men.

  3. Genre Analysis of Letters of Complaint

    Institute of Scientific and Technical Information of China (English)

    曹劲草

    2014-01-01

    This article makes a genre analysis of letter of complaint according to Swales’ theory in hope that some enlightenment wil be provided for the traders in writing letters of complaint in a more efficient way. The study focus on the structural features, grammatical features and lexical features.

  4. Cognitive Determinants of Early Letter Knowledge

    Science.gov (United States)

    Helal, Suha; Weil-Barais, Annick

    2015-01-01

    The present study investigated the general cognitive determinants of alphabetic letter knowledge. It involved 60 French kindergarten children (mean age: five years six months). Two test batteries were used: the CMS to evaluate general cognitive abilities (memory, attention, and learning), and the LKT to assess letter knowledge and its various…

  5. Design Improvements for Frequently Misrecognized Letters

    DEFF Research Database (Denmark)

    Beier, Sofie; Larson, Kevin

    2010-01-01

    To enhance typeface legibility we studied how to improve the design of individual letters. Three diff erent fonts were created, each containing several variations of the most frequently misrecognized letters. These variations were tested both with distance and short exposure methodologies. Creati...

  6. Prefix Codes: Equiprobable Words, Unequal Letter Costs

    OpenAIRE

    Golin, Mordecai; Young, Neal E.

    2002-01-01

    Describes a near-linear-time algorithm for a variant of Huffman coding, in which the letters may have non-uniform lengths (as in Morse code), but with the restriction that each word to be encoded has equal probability. [See also ``Huffman Coding with Unequal Letter Costs'' (2002).

  7. Reflection on Letter from Birmingham Jail

    Institute of Scientific and Technical Information of China (English)

    张远艳; 罗瑞

    2015-01-01

    "Letter from Birmingham Jail" is written by Martin Luther King,Jr.,who is a famous American civil rights leader.This essay attempts to analyze three major arguments in this letter to arouse people’s consciousness to cherish and protect our freedom.

  8. Reflection on Letter from Birmingham Jail

    Institute of Scientific and Technical Information of China (English)

    张远艳; 罗瑞

    2015-01-01

    Letter from Birmingham Jail” is written by Martin Luther King,Jr.,who is a famous American civil rights leader.This essay attempts to analyze three major arguments in this letter to arouse people’s consciousness to cherish and protect our freedom.

  9. Evolutionary theory in letters to the editor.

    Science.gov (United States)

    Silva, Eric Orion; Lowe, Clayton Cory

    2015-05-01

    This research note presents the results of a content analysis of 234 letters to the editors that discuss evolutionary theory and were published in American newspapers. We find that letters to the editor both support and hinder the cause of teaching evolutionary theory in American secondary schools. On the one hand, anti-evolutionary theory messages are marginalized in the letters section. This marginalization signals a low level of legitimacy for creationism. It might also contribute to the sense of tension that sustains creationist identities. On the other hand, relatively few letters explicitly note the fact that scientists or the scientific community accept evolution. Interestingly, the obscuration of the scientific community's support for evolutionary theory occurs both in letters supporting and opposing evolutionary theory. © The Author(s) 2014.

  10. Letter identification and the neural image classifier.

    Science.gov (United States)

    Watson, Andrew B; Ahumada, Albert J

    2015-02-12

    Letter identification is an important visual task for both practical and theoretical reasons. To extend and test existing models, we have reviewed published data for contrast sensitivity for letter identification as a function of size and have also collected new data. Contrast sensitivity increases rapidly from the acuity limit but slows and asymptotes at a symbol size of about 1 degree. We recast these data in terms of contrast difference energy: the average of the squared distances between the letter images and the average letter image. In terms of sensitivity to contrast difference energy, and thus visual efficiency, there is a peak around ¼ degree, followed by a marked decline at larger sizes. These results are explained by a Neural Image Classifier model that includes optical filtering and retinal neural filtering, sampling, and noise, followed by an optimal classifier. As letters are enlarged, sensitivity declines because of the increasing size and spacing of the midget retinal ganglion cell receptive fields in the periphery.

  11. Latin Classics in the Letters of Saint Jerome

    Directory of Open Access Journals (Sweden)

    Julijana Visočnik

    2002-12-01

    Full Text Available Saint Jerome, one of the most important Latin Fathers of the Church, was born in the 4th century AD in the town of Stridon, located somewhere on the border between Pannonia and Dalmatia. After finishing elementary school in his home town, he continued his education in Rome with the well-known teacher and grammarian Aelius Donatus, becoming acquainted with all the important Latin classics. In Rome, Jerome was baptised and after that he decided to become a monk. He dedicated his life to God and started writing prayers, translating the Bible and correcting its existing translations, and engaging in criticisms and polemics caused by contemporary events and practices. He also wrote over 120 letters, which were addressed to various people, some of them famous in their own right and some known today precisely through his writings. A lot of variety can be found in his letters: some of them are just short answers, while others grew to be independent books including discussions about moral, exegetic, and dogmatic questions. Letter XXII was written in the year 384 AD as an instruction for the virgin life of Julia Eustochium. In chapter 30, the reader is introduced to some facts about Jerome's life, as well as to the statement: "Ciceronianus es, non Christianus." This he heard in his feverish dreams, nightmares even, in which he was told not to read pagan literature any more. He promised not to, but the question inevitably arises if this was possible. He had already read and learnt by heart so many Latin classics that it was impossible for him to ignore them. Therefore it comes as no surprise that his writings are permeated with echoes of, or borrowings from, Horace, Virgil, Terence, Cicero, Plautus, Lucretius, Persius, Ovid, Martial, Quintilian, and Seneca. His letters also preserve a number of passages from their works. The Latin authors most frequently mentioned in the letters are Virgil, Horace, and Cicero - writers whose works were used as examples in

  12. Critical contrastive rhetoric: The influence of L2 letter writing instruction on L1letter writing

    Directory of Open Access Journals (Sweden)

    Mehrnoosh Fakharzadeh

    2014-08-01

    Full Text Available The present study employed critical contrastive rhetoric to investigate the L2 to L1 transfer of organizational pattern and directness level of speech acts in business complaint letters. By examining the L1 complaint letters of 30 tourism university students in two phases of study, pre and post instruction of English complaint letter, the study revealed that the rhetorical organization of Persian letters are in a state of hybridity. The post instruction comparison of letters, however, showed a tendency towards applying English conventions both in organization and directness level of complaint speech act in the L1 complaint letters. The results also revealed that after instruction the expert in the field of tourism viewed some letters as inappropriate in terms of politeness which is reflected through some lexical items.

  13. Addendum to the Closure Report for Corrective Action Unit 357: Mud Pits and Waste Dump, Nevada Test Site, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, Mark J

    2013-10-01

    This document constitutes an addendum to the Closure Report for Corrective Action Unit 357: Mud Pits and Waste Dump, Nevada Test Site, Nevada as described in the document Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order dated September 2013. The Use Restriction Removal document was approved by the Nevada Division of Environmental Protection on October 16, 2013. The approval of the UR Removal document constituted approval of each of the recommended UR removals. In conformance with the UR Removal document, this addendum consists of: This page that refers the reader to the UR Removal document for additional information The cover, title, and signature pages of the UR Removal document The NDEP approval letter The corresponding section of the UR Removal document This addendum provides the documentation justifying the cancellation of the UR for CAS 04-26-03, Lead Bricks. This UR was established as part of FFACO corrective actions and was based on the presence of lead contamination at concentrations greater than the action level established at the time of the initial investigation.

  14. Differences between English and Chinese Sales Promotion Letters

    Institute of Scientific and Technical Information of China (English)

    PANG Yu-yan

    2015-01-01

    This paper aims to figure out the differences in English and Chinese sales promotion letters by analyzing ten selected letters from business writing books and websites, which might provide more valuable information for businessmen in their sales promotion letter writing.

  15. Improving Cover-Letter Writing Skills of Individuals with Intellectual Disabilities

    Science.gov (United States)

    Pennington, Robert; Delano, Monica; Scott, Renee

    2014-01-01

    We evaluated a multicomponent intervention for improving the cover-letter writing skills of individuals with intellectual disabilities. An intervention that included modeling, self-monitoring, prompting, and feedback increased correct performance for all participants. In addition, the skill was demonstrated across audiences.

  16. Some Comments on the US Catholic Bishops’ Letter on War and Peace.

    Science.gov (United States)

    2014-09-26

    Christians were generally pacifists for the first 400 years of the Church, a fundamental justification for Christian war took shape under Constantine...demonstrates that the letter is not pacifist as some claim. There are seven criteria for judging when recourse to war (ju) all) is morally correct. First

  17. Improving Cover-Letter Writing Skills of Individuals with Intellectual Disabilities

    Science.gov (United States)

    Pennington, Robert; Delano, Monica; Scott, Renee

    2014-01-01

    We evaluated a multicomponent intervention for improving the cover-letter writing skills of individuals with intellectual disabilities. An intervention that included modeling, self-monitoring, prompting, and feedback increased correct performance for all participants. In addition, the skill was demonstrated across audiences.

  18. Statistical mechanics of letters in words.

    Science.gov (United States)

    Stephens, Greg J; Bialek, William

    2010-06-01

    We consider words as a network of interacting letters, and approximate the probability distribution of states taken on by this network. Despite the intuition that the rules of English spelling are highly combinatorial and arbitrary, we find that maximum entropy models consistent with pairwise correlations among letters provide a surprisingly good approximation to the full statistics of words, capturing ∼92% of the multi-information in four-letter words and even "discovering" words that were not represented in the data. These maximum entropy models incorporate letter interactions through a set of pairwise potentials and thus define an energy landscape on the space of possible words. Guided by the large letter redundancy we seek a lower-dimensional encoding of the letter distribution and show that distinctions between local minima in the landscape account for ∼68% of the four-letter entropy. We suggest that these states provide an effective vocabulary which is matched to the frequency of word use and much smaller than the full lexicon.

  19. Letters are functional in word identification.

    Science.gov (United States)

    Massaro, D W; Klitzke, D

    1977-05-01

    Are words identified as if they are single-unit patterns, or does letter processing mediate word identification? In the main, accuracy experiments have been found to support the mediated model, whereas recent reaction time experiments have been interpreted in favor of the single-unit pattern hypothesis. In the latter experiments, subjects could search for a target word in a test word as quickly as for a target letter in a test letter. The analysis of these results, however, did not consider the role of parallel processing of individual letters, lateral masking, limited capacity, and similarity between the target and test alternatives. In the present experiment, the advantage of parallel processing of letters in words was attenuated by manipulating similarity. The reaction times showed a processing advantage for single letters over words. This result as well as all of the previous results can be described in terms of processing mechanisms of the mediated model, the same mechanisms that have already been utilized to describe the accuracy of letter and word identification in tachistoscopic experiments.

  20. Radiation Emitting Product Corrective Actions and Recalls

    Data.gov (United States)

    U.S. Department of Health & Human Services — This database provides descriptions of radiation-emitting products that have been recalled under an approved corrective action plan to remove defective and...

  1. Culture and subculture in transactional letter writing

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    2000-01-01

    This study examines the relative contributions of subculture membership and mother-tongue status/target culture membership in writing transactional letters. We examined the letters accompanying articles initially submitted for publication by 26 NSE and 23 NNSE academics, and compared them...... to use appropriate language. The native non-professionals controlled some appropriate phrases, and were able to use appropriate vocabulary, but had very little idea of the rhetoric, while the non-native non-professionals produced grammatically competent letters that were inappropriate in both rhetoric...

  2. Comments on Letter (Phys. Rev. L, Vol.89, No. 10,2002) by D. Shapira and M. Saltmarsh

    CERN Document Server

    Taleyarkhan, Rusi P; Cho, JaeSeon; Lahey, Richard T; Nigmatulin, Robert I; Block, Robert C

    2013-01-01

    This article focuses on correcting several factual errors and critiques in the previously published Letter in Phys. Rev. L, Vol. 89, No. 10, 2022, by D. Shapira and M. Saltmarsh. The authors of the Letter did not perform their own "independent" experiments as claimed; they did not perform control experiments with normal acetone; and, neither did they monitor for tritium. It their Letter, the authors (D. Shapira and M. Saltmarsh) failed to disclose that the data they collected actually confirmed our claims of having observed statistically significant nuclear emissions in chilled, cavitated deuterated acetone.

  3. Visual perception of motor anticipation in cursive handwriting: influence of spatial and movement information on the prediction of forthcoming letters.

    Science.gov (United States)

    Orliaguet, J P; Kandel, S; Boë, L J

    1997-01-01

    The execution of a graphemic sequence is constrained by spatial demands that result in fluctuations of letter shape and movement time. When producing two letters (ll, le, or ln) the movement time and the letter shape of the first letter depend on the execution constraints of the second one. The motor system thus anticipates the production of the forthcoming graphemic sequence during the production of the first letter. An experiment is reported the aim of which was to examine whether the visual system could exploit this anticipatory information to predict the identity of the letter following the l. Different ls belonging to ll, le, and ln were presented on a screen. Subjects had to predict to which couple of letters (ll, le, or ln) the presented l belonged to, by using information on the shape of the l and/or the movement that produced it. Results showed that the percentages of correct responses were higher in the conditions where the stimulus provided kinematic information than in the condition in which only spatial information was available. The ability to predict the forthcoming letter seems to be mediated by implicit knowledge on motor anticipation rules.

  4. A letter from Janet Benshoof.

    Science.gov (United States)

    Benshoof, J

    1997-06-06

    This letter to readers of "Reproductive Freedom News" criticizes the American Medical Association's (AMA) Board of Trustees for endorsing a bill in the US Senate that would ban "partial-birth" abortions and allow the imprisonment of physicians who perform the procedure. The decision of the Board of Trustees was made in total disregard to the AMA bylaws, because the decision ran counter to the recommendations of an AMA task force that concluded that the AMA should take no action on this bill but seek to preserve the ability of physicians to use their discretion in providing medical care and the viability line in abortion legislation. The proposed criminal ban fails to contain a viability line; provides no exception to protect a woman's health, medical choice, or safety; and provides no exception in cases of fetal anomaly. The action by the Board of Trustees seriously undermines the work of the Center for Reproductive Law and Policy and gives abortion opponents ammunition to mount a serious challenge to the Roe vs. Wade decision. The AMA endorsement goes beyond simply stating that the procedure should never be used; it endorses giving physicians who perform such abortions, for whatever reason, prison terms. This position undermines two critical principles long upheld by the AMA: 1) that physicians must be able to carry out their medical responsibilities free from government interference and 2) that women have a fundamental right to decide on the appropriate provision of abortion services within their physician-patient relationship. The damage from this endorsement can and should be undone by the AMA's House of Delegates at their meeting in June 1997.

  5. Gender bias found in recommendation letters

    Science.gov (United States)

    Kruesi, Liz

    2016-11-01

    Female postdoctoral fellowship applicants are half as likely as their male counterparts to receive glowing recommendation letters, according to a study by researchers at Columbia University's Lamont-Doherty Earth Observatory (LDEO).

  6. Army Response Letter - signed February 3, 1989

    Science.gov (United States)

    A response letter to Ms. Hanmer regarding her request related to a permit application being considered by the New Orleans District Corps of Engineers for a project proposed by Plantation Landing Resort, Inc.

  7. Army Response Letter - signed April 27, 1988

    Science.gov (United States)

    Army response letter regarding a request to elevate the decision of the New England Division Engineer (DE) to issue a permit to the Maine Department of Transportation to construct a marine terminal at Sears Island.

  8. African Journals Online: Browse Alphabetically -- letter U

    African Journals Online (AJOL)

    Items 1 - 7 of 7 ... African Journals Online: Browse Alphabetically -- letter U ... English and other European languages and literatures, Chinese and other Asian languages and ... UNISWA Research Journal of Agriculture, Science and Technology.

  9. Why doctors do not answer referral letters

    African Journals Online (AJOL)

    Despite the obvious benefits to patient care, answers to referral letters .... value on brevity and educational value than specialists.9 As brevity is preferred, PHC doctors ... suggested that personal contact plays an important role in the decision.

  10. Scott's Lake Excavation Letters on Human Remains

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is two letters written about the repatriation of Santee Indian human remains and funerary objects to Santee Sioux Tribe. Includes an inventory of human remains...

  11. 2013 FEMA Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  12. African Journals Online: Browse Alphabetically -- letter D

    African Journals Online (AJOL)

    The journal publishes original research, case report/case series, letter to the editor, reviews of health ... Democracy & Development: Journal of West African Affairs ... Civic organisations and the new and innovative programmes, activities, and ...

  13. Stochastic Flips on Two-letter Words

    CERN Document Server

    Bodini, Olivier; Regnault, Damien

    2010-01-01

    This paper introduces a simple Markov process inspired by the problem of quasicrystal growth. It acts over two-letter words by randomly performing \\emph{flips}, a local transformation which exchanges two consecutive different letters. More precisely, only the flips which do not increase the number of pairs of consecutive identical letters are allowed. Fixed-points of such a process thus perfectly alternate different letters. We show that the expected number of flips to converge towards a fixed-point is bounded by $O(n^3)$ in the worst-case and by $O(n^{5/2}\\ln{n})$ in the average-case, where $n$ denotes the length of the initial word.

  14. Letter to President [Valentine National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Valentine National Wildlife Refuge Wilderness area....

  15. Due lettere di Friedrich Hölderlin

    Directory of Open Access Journals (Sweden)

    Friedrich Hölderlin

    2012-05-01

    Full Text Available Here's the first italian translation of two letters by Friedrich Hölderlin, written between November 1798 and January 1799 and adressed respectively to Christian Ludwig Neuffer (the first one and to Hölderlin's youngest brother Karl (the second one. Aim of these two letters is to clarify and to take a deeper look into the notion of lebendiges, the “living element”, which is at the heart of Hölderlins' poetics. Translated by Mariagrazia Portera.

  16. Attentional Processing of Letter Strings by Children.

    Science.gov (United States)

    Leclercq, Virginie; Siéroff, Eric

    2016-01-01

    Reading a letter string requires attentional orienting toward the beginning of the string (left-dominant orientation), followed by orienting along the string. These attentional-orienting processes differ according to the lexicality of the letter string: Sequential processes apply when reading nonwords or pseudowords, while words can be processed more globally. The aim of this study was to evaluate the development of these attentional processes involved in reading. We conducted two experiments in 6- (first grade), 7- (second grade), and 9-year-old (fourth grade) children, using a procedure that required the detection of a letter (Experiment 1) or a nonletter (Experiment 2) target in a string of five characters. The target character could occur in the second (left) or fourth (right) position in the string. Results showed an advantage for left nonletter targets as early as age 6 and of left letter targets as early as age 7. In 6-year-olds, only good readers detected a left letter target faster than a right letter target; others detected a right letter target faster. Thus, dominant orienting toward the beginning of the letter string is not fully developed in children before the second year of reading. A possibility is that beginning readers have difficulties inhibiting an attention-orienting bias toward the right visual field in linguistic tasks. The results also showed that the lexicality effect on these attentional processes develops gradually until the fourth year of reading. We believe that the procedure used in this study will be very valuable for evaluating attentional difficulties during reading acquisition.

  17. On the Commercial Features of Business Letters

    Institute of Scientific and Technical Information of China (English)

    邬娜

    2008-01-01

    Effective business communication is the"lifeblood"of every organization and a key to success in your business career. Generally,each trade or each business achieves an agreement and then draws up a contract after buyer and seller exchange business letter. Thus,a successful business letter is one of the most personal method to promote a business career. The paper informs how to write suc-cessful correspondence.

  18. Symbols of Pearl in The Scarlet letter

    Institute of Scientific and Technical Information of China (English)

    Li Aiqing

    2002-01-01

    This article evaluates The Scatet Letter with the help of analyzing the symbolic meanings of Pearl. In this article, the author attempts to propose the symbols of Pearl from four aspects: the function of the letter, the symbol of Hester's distillation of instinct;the symbol of freedom; the symbol of consummation. From the interpretation of the symbols of Pearl, it has been proved that Pearl becomes Hawthorne' s best vehicle to convey his attitudes toward Puritanism.

  19. On Coding Non-Contiguous Letter Combinations

    Directory of Open Access Journals (Sweden)

    Frédéric eDandurand

    2011-06-01

    Full Text Available Starting from the hypothesis that printed word identification initially involves the parallel mapping of visual features onto location-specific letter identities, we analyze the type of information that would be involved in optimally mapping this location-specific orthographic code onto a location-invariant lexical code. We assume that some intermediate level of coding exists between individual letters and whole words, and that this involves the representation of letter combinations. We then investigate the nature of this intermediate level of coding given the constraints of optimality. This intermediate level of coding is expected to compress data while retaining as much information as possible about word identity. Information conveyed by letters is a function of how much they constrain word identity and how visible they are. Optimization of this coding is a combination of minimizing resources (using the most compact representations and maximizing information. We show that in a large proportion of cases, non-contiguous letter sequences contain more information than contiguous sequences, while at the same time requiring less precise coding. Moreover, we found that the best predictor of human performance in orthographic priming experiments was within-word ranking of conditional probabilities, rather than average conditional probabilities. We conclude that from an optimality perspective, readers learn to select certain contiguous and non-contiguous letter combinations as information that provides the best cue to word identity.

  20. Analysis of US Food and Drug Administration Warning Letters: False Promotional Claims Relating to Prescription and Over-the-Counter Medications.

    Science.gov (United States)

    Salas, Maribel; Martin, Michelle; Pisu, Maria; McCall, Erin; Zuluaga, Alvaro; Glasser, Stephen P

    2008-03-01

    Recent studies have suggested that there has been an increase in the number of 'warning letters' issued by the US Food and Drug Administration (FDA) despite the publication of the FDA advertising guidelines. However, limited information is available on the description of warning letters. The objective of this study was to analyse the frequency and content of FDA warning letters in relation to promotional claims and discuss the influence of regulatory and industry constraints on promotion. All warning letters published by the FDA between 5 May 1995 and 11 June 2007 were reviewed. Warning letters related to promotional issues were included and analysed. Information related to the identification number, date of the warning letter, FDA division that issued the letter, drug name, manufacturer, specific warning problem, type of promotional material and requested action was extracted. Two independent investigators reviewed and classified each PDF file, any differences were discussed until a consensus was reached. Between May 1995 and June 2007 a total of 8692 warning letters were issued, of which 25% were related to drugs. Of these, 206 warning letters focused on drug promotion and were included in this study: 23% were issued in 2005, 15% in 2004 and 14% in 1998. In total, 47% of the warning letters were issued because of false or misleading unapproved doses and uses, 27% failed to disclose risks, 15% cited misleading promotion, 8% related to misleading labelling and 3% promoted false effectiveness claims. There is an important variation in the number of warning letters issued in the last decade, probably because of the increasing number of drugs approved by the FDA, drug withdrawal scandals, and the publication of the FDA and the Pharmaceutical Research and Manufacturers of America (PhRMA) guidelines. We found that benefit-related claims, such as unapproved uses or doses of drugs, and failure to disclose risks, are the main causes of FDA issued warning letters for

  1. Letter Position Dyslexia in Arabic: From Form to Position

    Science.gov (United States)

    Friedmann, Naama; Haddad-Hanna, Manar

    2012-01-01

    This study reports the reading of 11 Arabic-speaking individuals with letter position dyslexia (LPD), and the effect of letter form on their reading errors. LPD is a peripheral dyslexia caused by a selective deficit to letter position encoding in the orthographic-visual analyzer, which results in migration of letters within words, primarily of middle letters. The Arabic orthography is especially interesting for the study of LPD because Arabic letters have different forms in different positions in the word. As a result, some letter position errors require letter form change. We compared the rate of letter migrations that change letter form with migrations that do not change letter form in 10 Arabic-speaking individuals with developmental LPD, and one bilingual Arabic and Hebrew-speaking individual with acquired LPD. The results indicated that the participants made 40% letter position errors in migratable words when the resulting word included the letters in the same form, whereas migrations that changed letter form almost never occurred. The error rate of the Arabic-Hebrew bilingual reader was smaller in Arabic than in Hebrew. However, when only words in which migrations do not change letter form were counted, the rate was similar in Arabic and Hebrew. Hence, whereas orthographies with multiple letter forms for each letter might seem more difficult in some respects, these orthographies are in fact easier to read in some forms of dyslexia. Thus, the diagnosis of LPD in Arabic should consider the effect of letter forms on migration errors, and use only migratable words that do not require letter-form change. The theoretical implications for the reading model are that letter form (of the position-dependent type found in Arabic) is part of the information encoded in the abstract letter identity, and thus affects further word recognition processes, and that there might be a pre-lexical graphemic buffer in which the checking of orthographic well-formedness takes place

  2. 33 CFR 127.009 - Letter of recommendation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Letter of recommendation. 127.009... General § 127.009 Letter of recommendation. After the COTP receives the Letter of Intent under § 127.007(a) or (b), the COTP issues a Letter of Recommendation as to the suitability of the waterway for LNG...

  3. Neural Correlates of Top-Down Letter Processing

    Science.gov (United States)

    Liu, Jiangang; Li, Jun; Zhang, Hongchuan; Rieth, Cory A.; Huber, David E.; Li, Wu; Lee, Kang; Tian, Jie

    2010-01-01

    This fMRI study investigated top-down letter processing with an illusory letter detection task. Participants responded whether one of a number of different possible letters was present in a very noisy image. After initial training that became increasingly difficult, they continued to detect letters even though the images consisted of pure noise,…

  4. Representation of Letter Position in Spelling: Evidence from Acquired Dysgraphia

    Science.gov (United States)

    Fischer-Baum, Simon; McCloskey, Michael; Rapp, Brenda

    2010-01-01

    The graphemic representations that underlie spelling performance must encode not only the identities of the letters in a word, but also the positions of the letters. This study investigates how letter position information is represented. We present evidence from two dysgraphic individuals, CM and LSS, who perseverate letters when spelling: that…

  5. Orthographic Reading Deficits in Dyslexic Japanese Children: Examining the Transposed-Letter Effect in the Color-Word Stroop Paradigm

    Science.gov (United States)

    Ogawa, Shino; Shibasaki, Masahiro; Isomura, Tomoko; Masataka, Nobuo

    2016-01-01

    In orthographic reading, the transposed-letter effect (TLE) is the perception of a transposed-letter position word such as “cholocate” as the correct word “chocolate.” Although previous studies on dyslexic children using alphabetic languages have reported such orthographic reading deficits, the extent of orthographic reading impairment in dyslexic Japanese children has remained unknown. This study examined the TLE in dyslexic Japanese children using the color-word Stroop paradigm comprising congruent and incongruent Japanese hiragana words with correct and transposed-letter positions. We found that typically developed children exhibited Stroop effects in Japanese hiragana words with both correct and transposed-letter positions, thus indicating the presence of TLE. In contrast, dyslexic children indicated Stroop effects in correct letter positions in Japanese words but not in transposed, which indicated an absence of the TLE. These results suggest that dyslexic Japanese children, similar to dyslexic children using alphabetic languages, may also have a problem with orthographic reading. PMID:27303331

  6. Post-Approval Studies

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CDRH Post-Approval Studies Program encompasses design, tracking, oversight, and review responsibilities for studies mandated as a condition of approval of a...

  7. Blindness and the age of enlightenment: Diderot's letter on the blind.

    Science.gov (United States)

    Margo, Curtis E; Harman, Lynn E; Smith, Don B

    2013-01-01

    Several months after anonymously publishing an essay in 1749 with the title "Letter on the Blind for the Use of Those Who Can See," the chief editor of the French Encyclopédie was arrested and taken to the prison fortress of Vincennes just east of Paris, France. The correctly assumed author, Denis Diderot, was 35 years old and had not yet left his imprint on the Age of Enlightenment. His letter, which recounted the life of Nicolas Saunderson, a blind mathematician, was intended to advance secular empiricism and disparage the religiously tinged rationalism put forward by Rene Descartes. The letter's discussion of sensory perception in men born blind dismissed the supposed primacy of visual imagery in abstract thinking. The essay did little to resolve any philosophical controversy, but it marked a turning point in Western attitudes toward visual disability.

  8. 29 CFR 34.44 - Corrective and remedial action.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Corrective and remedial action. 34.44 Section 34.44 Labor Office of the Secretary of Labor IMPLEMENTATION OF THE NONDISCRIMINATION AND EQUAL OPPORTUNITY... Corrective and remedial action. (a) A Letter of Findings, Notice to Show Cause, or Initial Determination...

  9. Letter-Transposition Effects Are Not Universal: The Impact of Transposing Letters in Hebrew

    Science.gov (United States)

    Velan, Hadas; Frost, Ram

    2009-01-01

    We examined the effects of letter-transposition in Hebrew in three masked-priming experiments. Hebrew, like English has an alphabetic orthography where sequential and contiguous letter strings represent phonemes. However, being a Semitic language it has a non-concatenated morphology that is based on root derivations. Experiment 1 showed that…

  10. Alphabetic skills in preschool: a preliminary study of letter naming and letter writing.

    Science.gov (United States)

    Molfese, Victoria J; Beswick, Jennifer; Molnar, Andrew; Jacobi-Vessels, Jill

    2006-01-01

    Development of letter naming and writing (skills in writing first name, dictated and copied letters, and dictated and copied numbers) was examined in 79 preschool children (M age = 56 months). Skills were assessed in the fall to determine the status of these procedural skills that are components of alphabetic knowledge at the start of the school year. Children with high letter-naming scores also had high scores on letter writing, including dictated or copied letters and writing some or all of the letters of their names. Letter-naming skills were related to number-writing skills whether the numbers were dictated or copied. The highest writing scores were found for first name writing compared to writing or copying letters and numbers. A focus on the development of procedural knowledge in the preschool period may yield the hopep for impacts on later reading skills that has not been found in curricula emphasizing conceptual knowledge (e.g., knowledge of print concepts, book conventions).

  11. Analysis of reliability of professor recommendation letters based on concordance with self-introduction letter.

    Science.gov (United States)

    Kim, Sang Hyun

    2013-12-01

    The purpose of this study was to examine the concordance between a checklist's categories of professor recommendation letters and characteristics of the self-introduction letter. Checklists of professor recommendation letters were analyzed and classified into cognitive, social, and affective domains. Simple correlation was performed to determine whether the characteristics of the checklists were concordant with those of the self-introduction letter. The difference in ratings of the checklists by pass or fail grades was analyzed by independent sample t-test. Logistic regression analysis was performed to determine whether a pass or fail grade was influenced by ratings on the checklists. The Cronbach alpha value of the checklists was 0.854. Initiative, as an affective domain, in the professor's recommendation letter was highly ranked among the six checklist categories. Self-directed learning in the self-introduction letter was influenced by a pass or fail grade by logistic regression analysis (pprofessor recommendation letters and the sum of all characteristics in the self-introduction letter.

  12. ERP Correlates of Letter Identity and Letter Position Are Modulated by Lexical Frequency

    Science.gov (United States)

    Vergara-Martinez, Marta; Perea, Manuel; Gomez, Pablo; Swaab, Tamara Y.

    2013-01-01

    The encoding of letter position is a key aspect in all recently proposed models of visual-word recognition. We analyzed the impact of lexical frequency on letter position assignment by examining the temporal dynamics of lexical activation induced by pseudowords extracted from words of different frequencies. For each word (e.g., BRIDGE), we created…

  13. 76 FR 53851 - Effective Date of Requirement for Premarket Approval for Cardiovascular Permanent Pacemaker...

    Science.gov (United States)

    2011-08-30

    ... Approval for Cardiovascular Permanent Pacemaker Electrode; Correction AGENCY: Food and Drug Administration... development protocol for the class III preamendments device: Cardiovascular permanent pacemaker electrode. The...

  14. Comparison of visual acuity levels in pediatric patients with amblyopia using Wright figures, Allen optotypes, and Snellen letters.

    Science.gov (United States)

    Mocan, Mehmet Cem; Najera-Covarrubias, Mario; Wright, Kenneth W

    2005-02-01

    To compare and correlate the clinical performance of Wright figures in visual acuity assessments of pediatric patients with amblyopia to those obtained through Allen cards and Snellen letters. Best-corrected visual acuity of 26 amblyopic children were measured with the Wright figures(c), Snellen letters, and isolated Allen optotypes, respectively. Amblyopia was defined as two lines of visual acuity difference or a visual acuity level of 20/30 or lower as determined by Snellen chart. The results were evaluated for statistical intergroup differences using the Wilks' Lambda multivariate analysis of variance and for correlation using the Pearson correlation coefficient test. The mean age of the subjects was 8.27 +/- 2.46 years (range: 5 to 15 years). The mean logMAR values for the Wright figures(c), Snellen letters, and Allen optotypes were 0.40 +/- 0.20, 0.47 +/- 0.23, and 0.29 +/- 0.28, respectively. When compared with Snellen letters, the Wright figures correlated to a higher degree ( r = 0.46, P Snellen letter testing, the sensitivity of Wright figures(c) and Allen cards in diagnosing amblyopic eyes was 87.0 and 56.5%, respectively ( P = 0.016). Wright figures, designed primarily to evaluate the vision in the preliterate pediatric population, correlate more closely to Snellen letters and have a higher rate of correctly identifying amblyopia than isolated Allen optotypes in pediatric patients.

  15. [Changes in CIRUGIA ESPANOLA Letters to the Editor between 2000 and 2007].

    Science.gov (United States)

    Rosell-Pradas, Jorge; Sánchez-Cantalejo, Emilio

    2008-09-01

    To describe the frequency and bibliographic characteristics of letters to the editor in the journal, Cirugía Española published between 2000 and 2007 and to compare the differences in the periods between 2000-2003 and 2004-2007. A descriptive and cross-sectional study, using the letters to the editor published in Spanish surgery between 2000 and 2007, as observation units. The variables considered were: the number of letters according to the volume and year of publication, substantive content of the paper, text length, graphics resources use, number of signatories and their professional profile, institutions of the authors, by origin and number of Autonomous Communities and number of bibliographical references. To meet the second objective, we compared letters from the period 2000-2003 with the period 2004-2007 against the rest of variables considered as a result. We used descriptive statistics and statistical analysis for comparison of distributions (chi2), with a level of significance of p < 0.05, using the SPSS software (Version 15.0). We identified 312 documents classified as letters. Between 2002 and 2005 their number was small. Often referring to clinical cases 187 (59.9%) and related letters, 98 (31.4%). Of those, 81.1% met the standard length of the text and only 6 letters (1.9%) was the use of graphics exceeded. In 122 letters (39.1%) the permitted number of authors was exceeded. They were mostly contributed by surgeons, 238 cases (76.3%), usually a single hospital, with 294 letters (94.2%) mainly from, Catalonia, Andalusia, Madrid and Valencia. Only 58.1% of the letters complied with the permitted number of references. More related letters were published in the last period (59 letters; 42.1%) than during the years 2000-2003 (39 letters; 22.7%) (chi2 = 14.79; p < 0.001). The correct length of the text improved in the second period, 136 (97.1%), compared to the first 117 (68%) (chi2 = 42.67; p < 0.001. The graphics resources were used properly in both

  16. The Symbolic Significance of The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    张力

    2007-01-01

    As a great romantic novelist in America in 19th century, Hawthorne was outstanding in handling the application of symbolism. The Scarlet Letter is Hawthorne's most important symbolic novel, which stands as the best work of Hawthorne and one of the indubitable masterpieces of American literature. This thesis aims at the exploration of the usage of the symbolism in the novel. It mainly discusses the deep symbolic significance of the scarlet letter "A" and the little pearl. The scarlet letter is the central symbol of the novel. Its symbolic meaning changes from 'adultery' to 'able', even 'angelic' in the novel. It also examines the symbolic meanings of little Pearl and some typical natural surroundings such as the jail, the forest, the rosebush and so on.

  17. [Structured electronic consultation letter for shoulder disorders].

    Science.gov (United States)

    Paloneva, Juha; Oikari, Marjo; Ylinen, Jari; Ingalsuo, Minna; Ilkka, Kunnamo; Ilkka, Kiviranta

    2012-01-01

    Referral to a specialist has a significant influence on management of the patient and costs associated with the treatments. However, development and research of the process by which patients are referred has been almost neglected. Expectations considering the purpose, contents, and timing of the referral of the consulting physician and the consultant do not always meet. A structured, electronic consultation letter was developed to respond this need. Functionality and interactivity are the key elements of the referral, including (1) an electronic referral letter to a specialist, (2) interactive education in clinical examination and management of shoulder disorders, and (3) an instrument of clinical examination and documentation of shoulder disorders.

  18. A bread-and-butter letter

    Institute of Scientific and Technical Information of China (English)

    王道庚

    2007-01-01

    letter作“信”讲是很常用的词,私人信件是personal letter。业务信件叫做business letter,祝贺信是letter of congratulation,邀请信是letter of invitation等等。还有一种信是a bread—and—butter letter,你知道是什么信吗?我们知道bread and butter是涂有黄油的面包,那么,a bread—and—butter leuer就是“黄油面包信”吧?非也。

  19. Traditions of martyrdom in the Ignatian Letters

    Directory of Open Access Journals (Sweden)

    S. Fuhrmann

    2011-06-01

    Full Text Available The letters of Ignatius represent one of the key texts for the emergence of martyrdom during the second century AD in Christianity. This article is concerned with the question whether Ignatius contributed to a “theology of martyrdom” or whether he rather relied on previous traditions. The author argues, by undertaking an analysis of certain pragmatics and semantics, that the motif of martyrdom is solely used to buttress Ignatius’ claim for authority among his intended addressees by referring to an understanding of martyrdom that has its roots in the New Testament. An identification of the author of the letters with a historical martyr is regarded as unlikely.

  20. Visual and proprioceptive recognition of cursive letters in young children.

    Science.gov (United States)

    Vinter, Annie; Chartrel, Estelle

    2008-09-01

    Two experiments investigated visual and proprioceptive recognition of cursive letters in young children. In Experiment 1, children aged 3-5 years were asked to recognize a visually presented target letter after a 3s inspection time, from among two distracters: a highly and a moderately similar letter. Visual letter recognition improved rapidly between 3 and 5 years and was a function of the "uniqueness" of letter shape and of letter frequency. In Experiment 2, children aged 4-6 years were asked to recognize a target letter from among 2 distracters, after having traced over the letter in a "blind" condition, with their hand guided by the experimenter. Proprioceptive recognition developed more slowly than visual recognition, and was not a function of letter frequency. The results are discussed in terms of integration versus differentiation of perceptual information, and of the tendency to base recognition on local rather than global similarity.

  1. Representation of Letter Position in Spelling: Evidence from Acquired Dysgraphia

    Science.gov (United States)

    Fischer-Baum, Simon; McCloskey, Michael; Rapp, Brenda

    2010-01-01

    The graphemic representations that underlie spelling performance must encode not only the identities of the letters in a word, but also the positions of the letters. This study investigates how letter position information is represented. We present evidence from two dysgraphic individuals, CM and LSS, who perseverate letters when spelling: that is, letters from previous spelling responses intrude into subsequent responses. The perseverated letters appear more often than expected by chance in the same position in the previous and subsequent responses. We used these errors to address the question of how letter position is represented in spelling. In a series of analyses we determined how often the perseveration errors produced maintain position as defined by a number of alternative theories of letter position encoding proposed in the literature. The analyses provide strong evidence that the grapheme representations used in spelling encode letter position such that position is represented in a graded manner based on distance from both edges of the word. PMID:20378104

  2. Letters in the Forest: Global precedence effect disappears for letters but not for non-letters under reading-like conditions

    Directory of Open Access Journals (Sweden)

    Thomas eLachmann

    2014-07-01

    Full Text Available Normally-skilled reading involves special processing strategies for letters, which are habitually funneled into an abstract letter code. On the basis of previous studies we argue that this habit leads to the preferred usage of an analytic strategy for the processing of letters, while non-letters are preferably processed via a holistic strategy. The well-known Global Precedence Effect (GPE seems to contradict to this assumption, since, with compound, hierarchical figures, including letter items, faster responses are observed to the global than to the local level of the figure, as well as an asymmetric interference effect from global to local level. We argue that with letters these effects depend on presentation conditions; only when they elicit the processing strategies automatized for reading, an analytic strategy for letters in contrast to non-letters is to be expected. We compared the GPE for letters and non-letters in central viewing, with the global stimulus size close to the functional visual field in whole word reading (6.5o of visual angle and local stimuli close to the critical size for fluent reading of individual letters (.5o of visual angle. Under these conditions, the GPE remained robust for non-letters. For letters, however, it disappeared: letters showed no overall response time advantage for the global level and symmetric congruence effects (local-to-global as well as global-to local interference. We interpret these results as according to the view that reading is based on resident analytic visual processing strategies for letters.

  3. CLOSURE REPORT FOR CORRECTIVE ACTION UNIT 390: AREAS 9, 10, AND 12 SPILL SITES, NEVADA TEST SITE, NEVADA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-10-01

    Corrective Action Unit (CAU) 390 consists four Corrective Action Sites (CASs) located in Areas 9, 10, and 12 of the Nevada Test Site. The closure activities performed at the CASs include: (1) CAS 09-99-03, Wax, Paraffin: 2 cubic yards of drilling polymer was removed on June 20,2005, and transported to the Area 9 Landfill for disposal. (2) CAS 10-99-01, Epoxy Tar Spill: 2 cubic feet of asphalt waste was removed on June 20,2005, and transported to the Area 9 Landfill for disposal. (3) CAS 10-99-03, Tar Spills: 3 cubic yards of deteriorated asphalt waste was removed on June 20,2005, and transported to the Area 9 Landfill for disposal. (4) CAS 12-25-03, Oil Stains (2); Container: Approximately 16 ounces of used oil were removed from ventilation equipment on June 28,2005, and recycled. One CAS 10-22-19, Drums, Stains, was originally part of CAU 390 but was transferred out of CAU 390 and into CAU 550, Drums, Batteries, and Lead Materials. The transfer was approved by the Nevada Division of Environmental Protection on August 19,2005, and a copy of the approval letter is included in Appendix D of this report.

  4. Crowding Affects Letters and Symbols Differently

    Science.gov (United States)

    Grainger, Jonathan; Tydgat, Ilse; Issele, Joanna

    2010-01-01

    Five experiments examined crowding effects with letter and symbol stimuli. Experiments 1 through 3 compared 2-alternative forced-choice (2AFC) identification accuracy for isolated targets presented left and right of fixation with targets flanked either by 2 other items of the same category or a single item situated to the right or left of targets.…

  5. The Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App. In iProceedings of MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0 (pp. 221-222). London, England. Retrieved from http://www.medicine20congre

  6. Readerly and Writerly "Letters from the Park."

    Science.gov (United States)

    Conde, Susana

    1993-01-01

    Discusses in depth the film "Cartas del parque" ("Letters from the Park"), the first of six films in the "Amores Dificiles" series. Notes that the film is pervaded by the traditional overdetermination of gender roles. Suggests that an intrusive and authoritative narrator makes of this both a "readerly" and a…

  7. "Physical Review Letters" in the Classroom

    Science.gov (United States)

    Angiolillo, Paul J.; Lynch, Jonathan

    2010-01-01

    Ask any physicist what the preeminent journal in the field is, and I think the almost unanimous answer will be "Physical Review Letters" ("PRL"). This weekly journal of the American Physical Society publishes high-impact research from all the major subdisciplines of physics. This journal is not the one you would think is the first place a high…

  8. Reply to letter to the editor

    NARCIS (Netherlands)

    Woelders, H.

    2006-01-01

    In response to the letter by Dr. Amir Arav I would like to mention the following. The application of the principle of directional solidification to cryopreservation of living cells was, as far as I am aware, not the invention of Dr. Arav. It was first published and patented by Rubinsky (Berkeley,

  9. The Best Use of a Cover Letter

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    So when should you use a cover letter? Only as part of a limited, targeted campaign to reach potential employers. Take the time to research and understand a company before committing yourself on paper as a potential employee, if you have no idea what the company does,

  10. Varsity letters documenting modern colleges and universities

    CERN Document Server

    Samuels, Helen Willa

    1998-01-01

    A study of the functions of colleges and universities, Varsity Letters is intended to aid those responsible for the documentation of these institutions. Samuels offers specific advice about the records of modern colleges and universities and proposes a method to ensure their adequate documentation. She also offers a method to analyze and plan the preservation of records for any type of institution.

  11. Hester Prynne in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    赵丽

    2011-01-01

    The Scarlet Letter is the masterpiece of Nathaniel Hawthorne, one of the great writers in the nineteenth century America. Since it was published in the year of 1850, it has been reread in the circle of literary criticism..In the book, Hawthorne Portrays H

  12. SiD Letter of Intent

    CERN Document Server

    Aihara, H; Oreglia, M.; Berger, E.L.; Guarino, V.; Repond, J.; Weerts, H.; Xia, L.; Zhang, J.; Zhang, Q.; Srivastava, A.; Butler, J.M.; Goldstein, Joel; Velthuis, J.; Radeka, V.; Zhu, R.-Y.; Lutz, P.; de Roeck, A.; Elsener, K.; Gaddi, A.; Gerwig, H.; Grefe, C.; Klempt, W.; Linssen, L.; Schlatter, D.; Speckmayer, P.; Thom, J.; Yang, J.; Christian, D.C.; Cihangir, S.; Cooper, W.E.; Demarteau, M.; Fisk, H.E.; Garren, L.A.; Krempetz, K.; Kutschke, R.K.; Lipton, R.; Para, A.; Tschirhart, R.; Wenzel, H.; Yarema, R.; Grunewald, M.; Pankov, A.; U., Gomel State Tech.; Dutta, T.; Dauncey, P.D.; Balbuena, J.P.; Fleta, C.; Lozano, M.; Ullan, M.; Christian, G.B.; Faus-Golfe, A.; Fuster, J.; Lacasta, C.; Marinnas, C.; Vos, M.; Duarte, J.; Fernandez, M.; Gonzalez, J.; Jaramillo, R.; Lopez, Virto, A.; Martinez-Eivero, C.; Moya, D.; Ruiz-Mimeno, A.; Vila, I.; Colledani, C.; Dorokhov, A.; Hu-Guo, C.; Winter, M.; Moortgat-Pick, G.; Onoprienko, D.V.; Kim, G.N.; Park, H.; Adloff, C.; Blaha, J.; Blaising, J.-J.; Cap, S.; Chefdeville, M.; Drancourt, C.; Espargiliare, A.; Gaglione, R.; Geffroy, N.; Jacquemier, J.; Karyotakis, Y.; Prast, J.; Vouters, G.; Gronberg, J.; Walston, S.; Wright, D.; Sawyer, L.; Laloum, M.; Ciobanu, C.; Chauveau, J.; Savoy-Navarro, A.; Andricek, L.; Moser, H.-G.; Cowan, R.f.; Fisher, P.; Yamamoto, R.K.; Kenney, ClMl; Boos, E.E.; Merkin, M.; Chen, S.; Chakraborty, D.; Dyshkant, A.; Hedin, D.; Zutshi, V.; Galkin, V.; D'Ascenzo, N.; Ossetski, D.; Saveliev, V.; Kapusta, F.; De Masi, R.; Vrba, V.; Lu, C.; McDonald, K.T.; Smith, A.J.S.; Bortoletto, D.; Coath, R.; Crooks, J.; Damerell, C.; Gibson, M.; Nichols, A.; Stanitzki, M.; Strube, J.; Turchetta, R.; Tyndel, M.; Weber, M.; Worm, S.; Zhang, Z.; Barklow, T.L.; Belymam, A.; Breidenbach, M.; Cassell, R.; Craddock, W.; Deaconu, C.; Dragone, A.; Graf, N.A.; Haller, G.; Herbst, R.; Hewett, J.L.; Jaros, J.A.; Johnson, A.S.; Kim, P.C.; MacFarlane, D.B.; Markiewicz, T.; Maruyama, T.; McCormick, J.; Moffeit, K.; Neal, H.A.; Nelson, T.K.; Oriunno, M.; Partridge, R.; Peskin, M.E.; Rizzo, T.G.; Rowson, P.; Su, D.; Woods, M.; Chakrabarti, S.; Dieguez, A.; Garrido, Ll.; Kaminski, J.; Conway, J.S.; Chertok, M.; Gunion, J.; Holbrook, B.; Lander, R.L.; Tripathi, S.M.; Fadeyev, V.; Schumm, B.A.; Oreglia, M.; Gill, J.; Nauenberg, U.; Oleinik, G.; Wagner, S.R.; Ranjan, K.; Shivpuri, R.; Varner, G.S.; Orava, R.; Van Kooten, R.; Bilki, B.; Charles, M.; Kim, T.J.; Mallik, U.; Norbeck, E.; Onel, Y.; Brau, B.P.; Willocq, S.; Taylor, G.N.; Riles, Keith; Yang, H.-J.; Kriske, R.; Cremaldi, L.; Rahmat, R.; Lastovicka-Medin, G.; Seidel, S.; Hildreth, M.D.; Wayne, M.; Brau, J.E.; Frey, R.; Sinev, N.; Strom, D.M.; Torrence, E.; Banda, Y.; Burrows, P.N.; Devetak, E.; Foster, B.; Lastovicka, T.; Li, Y.-M.; Nomerotski, A.; Riera-Babures, J.; Vilasis-Cardona, X.; Manly, S.; Adeva, B.; Iglesias Escudero, C.; Vazquez Regueiro, P.; Saborido Silva, J.J.; Gallas Torreira, A.; Gao, D.; Jie, W.; Jungfeng, Y.; Li, C.; Liu, S.; Liu, Y.; Sun, Y.; Wang, Q.; Yi, J.; Yonggang, W.; Zhao, Z.; De, K.; Farbin, A.; Park, S.; Smith, J.; White, A.P.; Yu, J.; Lou, X.C.; Abe, T.; Aihara, H.; Iwasaki, M.; Lubatti, H.J.; Band, H.R.; Feyzi, F.; Prepost, R.; Karchin, P.E.; Milstene, C.; Baltay, C.; Dhawan, S.; Kwon, Y.-J.

    2009-01-01

    Letter of intent describing SiD (Silicon Detector) for consideration by the International Linear Collider IDAG panel. This detector concept is founded on the use of silicon detectors for vertexing, tracking, and electromagnetic calorimetry. The detector has been cost-optimized as a general-purpose detector for a 500 GeV electron-positron linear collider.

  13. Letter of the Editor-in-chief

    Institute of Scientific and Technical Information of China (English)

    Shiwen Wang; Mathew Sorrentino; Thach Nguyen

    2006-01-01

    @@ Dear Friends and Colleagues, In this letter, I would like to celebrate the second anniversary of the Journal of Geriatric Cardiology (JGC).With the help of all of you, friends and colleagues, readers,editorials consultants, authors and editorial staff, the JGC was able to grow and publish many quality papers from the world.

  14. Fallout from Chernobyl [Letters to the editor

    Energy Technology Data Exchange (ETDEWEB)

    Williams, E.D. (Addenbrooke' s Hospital, Cambridge (United Kingdom)); Abelin, T.; Egger, M. (Bern Univ. (Switzerland)) (and others)

    1994-11-12

    Six brief letters discuss the possible health effects of fallout from the Chernobyl reactor accident including an increase in thyroid cancer in children in Belarus, chromosomal abnormalities in workers from Latvia who cleared up the Chernobyl accident site, an increased trisomy 21 in Berlin but a lack of increased childhood leukaemia incidence in Greece. (UK).

  15. Researches Made on The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王舫

    2011-01-01

    Being the first American native novel,a great number of researches have been made on The Scarlet Letter.This paper collects some popular researches that have been made on this novel and classifies them into five perspectives --- romance,symbolism,Puritanism,feminism and psychoanalysis.

  16. Reply to letter to the editor

    NARCIS (Netherlands)

    Woelders, H.

    2006-01-01

    In response to the letter by Dr. Amir Arav I would like to mention the following. The application of the principle of directional solidification to cryopreservation of living cells was, as far as I am aware, not the invention of Dr. Arav. It was first published and patented by Rubinsky (Berkeley, CA

  17. An Unknown Letter by Maria Komornicka

    Directory of Open Access Journals (Sweden)

    Mateusz Bourkane

    2013-01-01

    Full Text Available The study presents an unpublished letter by Maria Komornicka, which the poet sent in July 1899 to her aunt, Aleksandra Oszacka. The epistolary communication, which contains several pieces of information about the life and activities of the poet living in Warsaw, can be a valuable material for researchers interested in her biography.

  18. 42 CFR 93.202 - Charge letter.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Charge letter. 93.202 Section 93.202 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  19. The anthrax letters: a medical detective story

    National Research Council Canada - National Science Library

    Cole, Leonard A

    2003-01-01

    .... Library of Congress Cataloging-in-Publication Data Cole, Leonard A., 1933The anthrax letters : a medical detective story / Leonard A. Cole. p. cm. Includes bibliographical references and index. ISBN 0-309-08881-X - ISBN 0-309-52584-5 (PDF) 1. Bioterrorism- United States. 2. Anthrax- United States. 3. Postal service- United States. 4. Victims of...

  20. The Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App. In iProceedings of MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0 (pp. 221-222). London, England. Retrieved from

  1. Samuel Beckett: Color, Letter, and Line.

    Science.gov (United States)

    Conley, Tom

    1985-01-01

    Through a bilingual reading of Beckett's "Mal vu mal dit," the illusion of painted relief for printed letters is created. Colors manifest themselves through the continual process of translation. The French translation adds color to the black and white English text. (DF)

  2. Application of Politeness Strategies in Business Letters

    Institute of Scientific and Technical Information of China (English)

    杨雅婷

    2015-01-01

    As is known to all,businesses are very image - conscious. Most of the companies try to conduct themselves decently and politely in their business transactions,among which business letters are major manifestations of politeness. Application of Politeness Strategies is of great significance.

  3. Letters to a Young Education Reformer

    Science.gov (United States)

    Hess, Frederick M.

    2017-01-01

    In "Letters to a Young Education Reformer," Frederick M. Hess distills knowledge from twenty-five years of working in and around school reform. Inspired by his conversations with young, would-be reformers who are passionate about transforming education, the book offers a window into Hess's thinking about what education reform is and…

  4. Introduction to Literary Criticism: "The Scarlet Letter."

    Science.gov (United States)

    Lawrence, Lisa

    This course seeks to provide high school students the opportunity to sharpen their critical thinking skills and use of language through acquaintance with some ideas of literary criticism. The course features Nathaniel Hawthorne's "The Scarlet Letter," assuming that the students have just finished reading that American classic novel. The…

  5. An Open Letter to Ninth Graders

    Science.gov (United States)

    Sullivan, Patrick

    2009-01-01

    Many studies and reports in recent years have argued that there's an important "expectations gap" between the skills students are typically bringing to college and what college teachers think students should be bringing with them to college. This article, presented in the form of an open letter to first-year high school students, is an attempt…

  6. African Journals Online: Browse Alphabetically -- letter W

    African Journals Online (AJOL)

    Items 1 - 7 of 7 ... African Journals Online: Browse Alphabetically -- letter W ... treatment and disposal of sewage sludge; environmental pollution ... Water SA is the WRC's accredited scientific journal which contains ... Aims: The aims of the Journal are: To provide a medium for international dissemination of information about ...

  7. Letter to President [Back Bay National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Assistant Secretary of the Interior to the President regarding the establishment of the Back Bay Wilderness area. The letter...

  8. Letter to President [Laguna Atascosa National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Laguna Atascosa Wilderness area. The letter...

  9. 50 CFR 216.257 - Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE... Mexico § 216.257 Letters of Authorization. (a) A Letter of Authorization, unless suspended or...

  10. Letter to President [Cedar Island National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Assistant Secretary of the Interior to the President regarding the establishment of the Cedar Island Wilderness area. The letter...

  11. Can words be read without abstract letter identities?

    Directory of Open Access Journals (Sweden)

    Simon Fischer-Baum

    2014-04-01

    CH’s acquired dyslexia and dysgraphia left him with a profound impairment in processing abstract letter identities. This impairment affected his ability to process strings of letters in a variety of tasks; for example nonword reading, spelling, recognizing orally spelled words. However, while impaired, his single word reading was surprisingly good given his single letter impairment, suggesting an additional route to word meaning from visually-presented familiar words that does not require abstract letter identities.

  12. Transposed-Letter and Laterality Effects in Lexical Decision

    Science.gov (United States)

    Perea, Manuel; Fraga, Isabel

    2006-01-01

    Two divided visual field lexical decision experiments were conducted to examine the role of the cerebral hemispheres in transposed-letter similarity effects. In Experiment 1, we created two types of nonwords: nonadjacent transposed-letter nonwords ("TRADEGIA"; the base word was "TRAGEDIA," the Spanish for "TRAGEDY") and two-letter different…

  13. Letter representations in writing: An fMRI adaptation approach

    Directory of Open Access Journals (Sweden)

    Olivier eDufor

    2013-10-01

    Full Text Available Abstract:Behavioral and neuropsychological research in reading and spelling has provided evidence for the role of the following types of orthographic representations in letter writing: letter forms, letter case, and abstract letter identities. We report on the results of an fMRI investigation designed to identify the neural substrates of these different representational types. Using a neural adaptation paradigm we examined the neural distribution of inhibition and release from inhibition in a letter-writing task in which, on every trial, participants produced three repetitions of the same letter and a fourth letter that was either identical to (no-change trial or different from the previous three (change trial. Change trials involved a change in the shape, case and/or identity of the letter. After delineating the general letter writing network by identifying areas that exhibited significant neural adaptation effects on no-change trials, we used deconvolution analysis to examine this network for effects of release from inhibition on change trials. In this way we identified regions specifically associated with the representation of letter shape (left SFS and SFG/pre-CG and letter identity (left fusiform gyrus or both (cerebellum, post-central gyrus and middle frontal gyrus. No regions were associated with the representation of letter case. This study showcases an investigational approach that allows for the differentiation of the neurotopography of the representational types that are key to our ability to produce written language.

  14. Return to sender: Constantijn Huygens as a man of letters

    NARCIS (Netherlands)

    Gosseye, L.; Blom, F.; Leerintveld, A.

    2013-01-01

    Return to Sender takes as its starting point Constantijn Huygens’ letters and shows us the author in his different guises: intimus of René Descartes, translator of John Donne, collector of art, writer of flirtatious love letters and the author of a long consolatory letter-poem for an ailing friend w

  15. Covert Reading of Letters in a Case of Global Alexia

    Science.gov (United States)

    Volpato, Chiara; Bencini, Giulia; Meneghello, Francesca; Piron, Lamberto; Semenza, Carlo

    2012-01-01

    This study describes the case of a global alexic patient with a severe reading deficit affecting words, letters and Arabic numbers, following a left posterior lesion. The patient (VA) could not match spoken letters to their graphic form. A preserved ability to recognize shape and canonical orientation of letters indicates intact access to the…

  16. 48 CFR 52.228-14 - Irrevocable Letter of Credit.

    Science.gov (United States)

    2010-10-01

    ... Credit. 52.228-14 Section 52.228-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION....228-14 Irrevocable Letter of Credit. As prescribed in 28.204-4, insert the following clause: Irrevocable Letter of Credit (DEC 1999) (a) “Irrevocable letter of credit” (ILC), as used in this clause...

  17. 31 CFR 535.416 - Letters of credit.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Letters of credit. 535.416 Section... § 535.416 Letters of credit. (a) Question. Prior to the effective date, a bank subject to the jurisdiction of the United States has issued or confirmed a documentary letter of credit for a non-Iranian...

  18. Perceptual-Motor Complexity of Printed and Cursive Letters.

    Science.gov (United States)

    Meulenbroek, Ruud G. J.; Van Galen, Gerard P.

    1990-01-01

    Seventy-five Dutch elementary school students wrote letters of a cursive alphabet after presentation of printed and cursive letters. Analysis revealed that spatial ambiguity, allographic variability, contextual ambiguity, and letter frequency are determinants of the time needed by children for perceiving printed and producing corresponding cursive…

  19. 33 CFR 62.43 - Numbers and letters.

    Science.gov (United States)

    2010-07-01

    ... letters. (a) All solid red and solid green aids are numbered, with red aids bearing even numbers and green... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Numbers and letters. 62.43... to assist in their identification, or to indicate their purpose. Sidemarks may carry letters...

  20. Transposed-Letter and Laterality Effects in Lexical Decision

    Science.gov (United States)

    Perea, Manuel; Fraga, Isabel

    2006-01-01

    Two divided visual field lexical decision experiments were conducted to examine the role of the cerebral hemispheres in transposed-letter similarity effects. In Experiment 1, we created two types of nonwords: nonadjacent transposed-letter nonwords ("TRADEGIA"; the base word was "TRAGEDIA," the Spanish for "TRAGEDY") and two-letter different…

  1. A Logical Letter-Sound System in Five Phonic Generalizations

    Science.gov (United States)

    Gates, Louis; Yale, Ian

    2011-01-01

    In five phonic generalizations, this article introduces a logical system of letter-sound relationships. Ranging from 91% to 99% phonic transparency, these statements generalize a study of 16,928 words in children's literature. The r-controlled vowels aside, the analysis shows 54 basic transparent letters and letter combinations, 39 transparent…

  2. Parents' Talk about Letters with Their Young Children

    Science.gov (United States)

    Treiman, Rebecca; Schmidt, John; Decker, Kristina; Robins, Sarah; Levine, Susan C.; Demir, Özlem E.

    2015-01-01

    A literacy-related activity that occurs in children's homes--talk about letters in everyday conversations--was examined using data from 50 children who were visited every 4 months between 14 and 50 months. Parents talked about some letters, including those that are common in English words and the first letter of their children's names, especially…

  3. Michael Maier--nine newly discovered letters.

    Science.gov (United States)

    Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

    2014-02-01

    The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony.

  4. Resource Letter QI-1: Quantum Information

    Science.gov (United States)

    Strauch, Frederick W.

    2016-07-01

    This Resource Letter surveys the history and modern developments in the field of quantum information. It is written to guide advanced undergraduates, beginning graduate students, and other new researchers to the theoretical and experimental aspects of this field. The topics covered include quantum states and processes, quantum coding and cryptography, quantum computation, the experimental implementation of quantum information processing, and the role of quantum information in the fundamental properties and foundations of physical theories.

  5. Resource Letter: TE-1: Teaching electronics

    Science.gov (United States)

    Henry, Dennis C.

    2002-01-01

    This Resource Letter examines the evolution, roles, and content of courses in electronics in the undergraduate physics curriculum, and provides a guide to resources for faculty teaching such courses. It concludes with a brief section addressing problems of electromagnetic interference in electronic systems, and provides an introduction to the literature and practice of electromagnetic compatibility. I have included textbooks, reference books, articles, collections of laboratory experiments and projects, sources of equipment and parts, software packages, videos, and websites.

  6. Essay: reflections on Physical Review Letters.

    Science.gov (United States)

    Lazarus, David

    2008-08-01

    During my tenure as APS Editor-in-Chief Physical Review Letters changed from a journal whose authors were mostly from the U.S. to one whose authors were mostly from abroad. I encouraged authors to publicize their work even before their papers were accepted for publication. And I sought to raise the quality of the papers that were published even higher than before.

  7. An open letter to Magic Johnson.

    Science.gov (United States)

    Pazin, G J

    1992-01-01

    The last installment in this series dealt with post-test counseling of a person whose HIV test was negative. The plan was to provide counseling for an HIV-infected person in this installment. NBA basketball star Magic Johnson's surprise announcement on November 7, 1991, of his infection with HIV has provided an unexpected opportunity to counsel a well-known person through an "open letter."

  8. Culture and subculture in transactional letter writing

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    2000-01-01

    with efforts to write such letters by 21 NSE and 23 NNSE non-professionals (British undergraduates and overseas English teachers). The results showed that the non-native professionals by and large perceived the rhetorical demands of the situation similarly to native professionals but were a little less likely...... and language. Thus the teaching approach for writing depends crucially on the status of the learners, and to teach lexical phrases is particularly important for non-natives....

  9. Osterc's letters to Milojević

    Directory of Open Access Journals (Sweden)

    Milin Melita B.

    2002-01-01

    Full Text Available The correspondence between two of the most important composers in Yugoslavia during the period between the two world wars: Miloje Milojević (1884-1946, a Serb living in Belgrade, and Slavko Osterc (1895-1946, Slovene living in Ljubljana, gives us valuable insight into their musical aspirations ambitions, relations to other colleagues, the functioning of musical institutions and the cultural and even political climate of the times. The stylistic features of their works are basically different, Milojević being a modernist with late romantic roots, while Osterc was inclined to objectivity of the neoclassical and "constructive expressionist type. The main topics of their correspondence include: the activities of the Yugoslav section of the International Society for Contemporary Music, in which they were very much involved, and the efforts they made to have their works performed both in the country and abroad. Milojević and Osterc maintained very good relations throughout the period covered by this exchange of letters, that is from 1933-1941 (Osterc's last letter was sent three months before his death in May 1941 and their correspondence provides evidence of several instances of the mutual generosity, as they helped each other in their careers. The portion of this correspondence that is kept in Ljubljana - Milojević's letters to Osterc - has already been published and analyzed by Dragotin Cvetko. As such, the edition of the remaining correspondence, Osterc's letters to Milojević, that is kept in the private archive of Milojević's grandson Vlastimir Trajković in Belgrade, completes the picture. The language Osterc used was his mother tongue, Slovenian, with "borrowings" from the Serbian, the result being an often amusing mixture of the two.

  10. Eye exercises enhance accuracy and letter recognition, but not reaction time, in a modified rapid serial visual presentation task.

    Directory of Open Access Journals (Sweden)

    Paula Di Noto

    Full Text Available Eye exercises have been prescribed to resolve a multitude of eye-related problems. However, studies on the efficacy of eye exercises are lacking, mainly due to the absence of simple assessment tools in the clinic. Because similar regions of the brain are responsible for eye movements and visual attention, we used a modified rapid serial visual presentation (RSVP to assess any measurable effect of short-term eye exercise in improvements within these domains. In the present study, twenty subjects were equally divided into control and experimental groups, each of which performed a pre-training RSVP assessment where target letters, to which subjects were asked to respond to by pressing a spacebar, were serially and rapidly presented. Response time to target letters, accuracy of correctly responding to target letters, and correct identification of target letters in each of 12 sessions was measured. The experimental group then performed active eye exercises, while the control group performed a task that minimized eye movements for 18.5 minutes. A final post-training RSVP assessment was performed by both groups and response time, accuracy, and letter identification were compared between and within subject groups both pre- and post-training. Subjects who performed eye exercises were more accurate in responding to target letters separated by one distractor and in letter identification in the post-training RSVP assessment, while latency of responses were unchanged between and within groups. This suggests that eye exercises may prove useful in enhancing cognitive performance on tasks related to attention and memory over a very brief course of training, and RSVP may be a useful measure of this efficacy. Further research is needed on eye exercises to determine whether they are an effective treatment for patients with cognitive and eye-related disorders.

  11. Eye exercises enhance accuracy and letter recognition, but not reaction time, in a modified rapid serial visual presentation task.

    Science.gov (United States)

    Di Noto, Paula; Uta, Sorin; DeSouza, Joseph F X

    2013-01-01

    Eye exercises have been prescribed to resolve a multitude of eye-related problems. However, studies on the efficacy of eye exercises are lacking, mainly due to the absence of simple assessment tools in the clinic. Because similar regions of the brain are responsible for eye movements and visual attention, we used a modified rapid serial visual presentation (RSVP) to assess any measurable effect of short-term eye exercise in improvements within these domains. In the present study, twenty subjects were equally divided into control and experimental groups, each of which performed a pre-training RSVP assessment where target letters, to which subjects were asked to respond to by pressing a spacebar, were serially and rapidly presented. Response time to target letters, accuracy of correctly responding to target letters, and correct identification of target letters in each of 12 sessions was measured. The experimental group then performed active eye exercises, while the control group performed a task that minimized eye movements for 18.5 minutes. A final post-training RSVP assessment was performed by both groups and response time, accuracy, and letter identification were compared between and within subject groups both pre- and post-training. Subjects who performed eye exercises were more accurate in responding to target letters separated by one distractor and in letter identification in the post-training RSVP assessment, while latency of responses were unchanged between and within groups. This suggests that eye exercises may prove useful in enhancing cognitive performance on tasks related to attention and memory over a very brief course of training, and RSVP may be a useful measure of this efficacy. Further research is needed on eye exercises to determine whether they are an effective treatment for patients with cognitive and eye-related disorders.

  12. A Retrospective Analysis Comparing the New Standardized Letter of Recommendation in Dermatology with the Classic Narrative Letter of Recommendation.

    Science.gov (United States)

    Kaffenberger, Jessica A; Mosser, Joy; Lee, Grace; Pootrakul, Llana; Harfmann, Katya; Fabbro, Stephanie; Faith, Esteban Fernandez; Carr, David; Plotner, Alisha; Zirwas, Matthew; Kaffenberger, Benjamin H

    2016-09-01

    Background: In an effort to avoid numerous problems associated with narrative letters of recommendation, a dermatology standardized letter of recommendation was utilized in the 2014-2015 resident application cycle. Objective: A comparison of the standardized letter of recommendation and narrative letters of recommendation from a single institution and application cycle to determine if the standardized letter of recommendation met its original goals of efficiency, applicant stratification, and validity. Methods: Eight dermatologists assessed all standardized letters of recommendation/narrative letters of recommendation pairs received during the 2014-2015 application cycle. Five readers repeated the analysis two months later. Each letter of recommendation was evaluated based on a seven question survey. Letter analysis and survey completion for each letter was timed. Results: Compared to the narrative letters of recommendation, the standardized letter of recommendation is easier to interpret (precommendation are also faster to interpret (precommendation (precommendation appears to be meeting its initial goals of 1) efficiency, 2) applicant stratification, and 3) validity. (J Clin Aesthet Dermatol. 2016;9(9):36-2.).

  13. Identifying Interventions for Improving Letter Formation: A Brief Experimental Analysis of Students with Intellectual Disabilities

    Directory of Open Access Journals (Sweden)

    E. Rüya ÖZMEN

    2016-09-01

    Full Text Available As a group, students with intellectual disabilities display difficulties in a wide range of academic skills, including the acquisition of basic academic skills such as literacy. Early writing and reading skills must be supported to prepare students with intellectual disabilities to learn to read and write. The goal of this study was to replicate and extend the current research on Brief Experimental Analysis with letter formation. Three students with intellectual disabilities participated in the study. A brief multi-element design was used to test effectiveness of four interventions on letter formation. These interventions included goal setting plus contingent reinforcement, graphical feedback, error correction and modeling. For one student, modeling was effective; for the two remaining students, goal setting plus contingent reinforcement was effective. The results of this study extend the BEA literature by investigating the effects of interventions for improving letter formation in students with intellectual disabilities. The study findings suggest that using BEA to assess the relative contribution of each intervention can identify the most effective interventions for improving letter formation in students with intellectual disabilities.

  14. Drugs Approved for Hodgkin Lymphoma

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Hodgkin Lymphoma This page lists cancer drugs approved by ... that are not listed here. Drugs Approved for Hodgkin Lymphoma Adcetris (Brentuximab Vedotin) Ambochlorin (Chlorambucil) Amboclorin (Chlorambucil) ...

  15. Drugs Approved for Lung Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Lung Cancer This page lists cancer drugs approved by the ... listed here. Drugs Approved for Non-Small Cell Lung Cancer Abitrexate (Methotrexate) Abraxane (Paclitaxel Albumin-stabilized Nanoparticle Formulation) ...

  16. Drugs Approved for Thyroid Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Thyroid Cancer This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Thyroid Cancer Cabozantinib-S-Malate Caprelsa (Vandetanib) Cometriq (Cabozantinib-S-Malate) Doxorubicin ...

  17. Neural correlates of letter reversal in children and adults.

    Science.gov (United States)

    Blackburne, Liwei King; Eddy, Marianna D; Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D E

    2014-01-01

    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging) and the electrophysiological correlates (via event-related potentials or ERPs) of this phenomenon in children, ages 5-12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA) in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing.

  18. Neural correlates of letter reversal in children and adults.

    Directory of Open Access Journals (Sweden)

    Liwei King Blackburne

    Full Text Available Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging and the electrophysiological correlates (via event-related potentials or ERPs of this phenomenon in children, ages 5-12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing.

  19. Gender differences in recommendation letters for postdoctoral fellowships in geoscience

    Science.gov (United States)

    Dutt, Kuheli; Pfaff, Danielle L.; Bernstein, Ariel F.; Dillard, Joseph S.; Block, Caryn J.

    2016-11-01

    Gender disparities in the fields of science, technology, engineering and mathematics, including the geosciences, are well documented and widely discussed. In the geosciences, despite receiving 40% of doctoral degrees, women hold less than 10% of full professorial positions. A significant leak in the pipeline occurs during postdoctoral years, so biases embedded in postdoctoral processes, such as biases in recommendation letters, may be deterrents to careers in geoscience for women. Here we present an analysis of an international data set of 1,224 recommendation letters, submitted by recommenders from 54 countries, for postdoctoral fellowships in the geosciences over the period 2007-2012. We examine the relationship between applicant gender and two outcomes of interest: letter length and letter tone. Our results reveal that female applicants are only half as likely to receive excellent letters versus good letters compared to male applicants. We also find no evidence that male and female recommenders differ in their likelihood to write stronger letters for male applicants over female applicants. Our analysis also reveals significant regional differences in letter length, with letters from the Americas being significantly longer than any other region, whereas letter tone appears to be distributed equivalently across all world regions. These results suggest that women are significantly less likely to receive excellent recommendation letters than their male counterparts at a critical juncture in their career.

  20. Neural Correlates of Letter Reversal in Children and Adults

    Science.gov (United States)

    Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D. E.

    2014-01-01

    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging) and the electrophysiological correlates (via event-related potentials or ERPs) of this phenomenon in children, ages 5–12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA) in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing. PMID:24859328

  1. Letter-by-letter processing in the phonological conversion of multiletter graphemes: searching for sounds in printed pseudowords.

    Science.gov (United States)

    Peereman, Ronald; Brand, Muriele; Rey, Arnaud

    2006-02-01

    Current models of word reading differ in their descriptions of how print-to-sound conversion is performed. Whereas a parallel procedure is generally assumed, the dual-route cascaded model developed by Coltheart and colleagues (Coltheart, Rastle, Perry, Langdon, and Ziegler, 2001) holds that the nonlexical conversion operates letter by letter, serially from left to right. An interesting aspect of the hypothesized serial procedure is that only the first letter of two-letter graphemes is thought to cause activation of its corresponding phonological code, the second letter of multiletter graphemes being directly merged with the preceding letter to form a complex grapheme. This hypothesis was examined in a task in which participants had to detect target phonemes in visually presented pseudowords. The data suggest that phonological codes associated with all the letters of the multiletter graphemes are activated.

  2. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North America,...

  3. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North...

  4. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North America,...

  5. Drugs Approved for Retinoblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for retinoblastoma. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  6. Drugs Approved for Neuroblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for neuroblastoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  7. Premarket Approvals (PMA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — Premarket approval by FDA is the required process of scientific review to ensure the safety and effectiveness of all devices classified as Class III devices. An...

  8. Premarket Approvals (PMA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — Premarket approval by FDA is the required process of scientific review to ensure the safety and effectiveness of all devices classified as Class III devices. An...

  9. Resource Letter NO-1: Nonlinear Optics

    Science.gov (United States)

    Garmire, Elsa

    2011-03-01

    This Resource Letter provides a guide to the literature on nonlinear optics. Books, journals, and websites are introduced that cover the general subject. Journal articles and websites are cited covering the following topics: second-order nonlinearities in transparent media including second-harmonic generation and optical parametric oscillation, third-order and higher nonlinearities, nonlinear refractive index, absorptive nonlinearities such as saturable absorption and multiphoton absorption, and scattering nonlinearities such as stimulated Raman scattering and stimulated Brillouin scattering. Steady-state and transient phenomena, fiber optics, solitons, nonlinear wave mixing, optical phase conjugation, nonlinear spectroscopy, and multiphoton microscopy are all outlined.

  10. Letters to Solovine 1906-1955

    CERN Document Server

    Einstein, Albert

    2011-01-01

    A provocative collection of letters to his longtime friend and translator that spans Einstein's career and reveals the inner thoughts and daily life of a transformative genius From their early days as tutor and scholar, discussing philosophy over Spartan dinners, to their work together to publish Einstein's books in Europe, in Maurice Solovine Einstein found both an engaged mind and a loyal friend. While Einstein frequently shared his observations on science, politics, philosophy, and religion in his correspondence with Solovine, he was just as likely to express his feelings about everyday l

  11. Resource Letter OSE-1: Observing Solar Eclipses

    Science.gov (United States)

    Pasachoff, Jay M.; Fraknoi, Andrew

    2017-07-01

    This Resource Letter provides a guide to the available literature, listing selected books, articles, and online resources about scientific, cultural, and practical issues related to observing solar eclipses. It is timely, given that a total solar eclipse will cross the continental United States on August 21, 2017. The next total solar eclipse path crossing the U.S. and Canada will be on April 8, 2024. In 2023, the path of annularity of an annular eclipse will cross Mexico, the United States, and Canada, with partial phases visible throughout those countries.

  12. Algoritmi matematici nelle lettere di Gerbert

    Science.gov (United States)

    Rossi, P.

    The content of Gerbert's "scientific" letters is analyzed in detail, with special emphasis on arithmetical and geometrical issues, such as multiplication and division rules related to the use of abacus, superparticular numbers and evaluation of the area of an equilateral triangle. It is shown that Gerbert's area formula, albeit based on rational fractions, could hardly be conceived without knowledge of Pythagoras' theorem. This fact casts a light also on the astronomical tools created by Gerbert, where the didactical aspect cannot be separated from the accuracy of the demonstrations and of the measurements.

  13. 75 FR 30386 - Preferred Supplier Program (PSP); Correction

    Science.gov (United States)

    2010-06-01

    ... Department of the Navy Preferred Supplier Program (PSP); Correction AGENCY: Department of the Navy, DoD.... Instructions: Please submit comments only and cite ``Proposed DON PSP Policy Letter'' in all correspondence... most recent fiscal year. Other contractors may apply to join the PSP. DASN (A&LM) shall evaluate...

  14. ERP correlates of letter identity and letter position are modulated by lexical frequency

    Science.gov (United States)

    Vergara-Martínez, Marta; Perea, Manuel; Gómez, Pablo; Swaab, Tamara Y.

    2013-01-01

    The encoding of letter position is a key aspect in all recently proposed models of visual-word recognition. We analyzed the impact of lexical frequency on letter position assignment by examining the temporal dynamics of lexical activation induced by pseudowords extracted from words of different frequencies. For each word (e.g., BRIDGE), we created two pseudowords: A transposed-letter (TL: BRIGDE) and a replaced-letter pseudoword (RL: BRITGE). ERPs were recorded while participants read words and pseudowords in two tasks: Semantic categorization (Experiment 1) and lexical decision (Experiment 2). For high-frequency stimuli, similar ERPs were obtained for words and TL-pseudowords, but the N400 component to words was reduced relative to RL-pseudowords, indicating less lexical/semantic activation. In contrast, TL- and RL-pseudowords created from low-frequency stimuli elicited similar ERPs. Behavioral responses in the lexical decision task paralleled this asymmetry. The present findings impose constraints on computational and neural models of visual-word recognition. PMID:23454070

  15. Correcting Non-Word Errors Using a Combined Method

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The weighted edit distance and metaphone + algorithm are combined to correct the non-word errors. The speed is also optimized based on the observation that people rarely make mistakes in the initial letter of a word. A spelling checker is designed for an automatic detection and correction system for student essays. To evaluate the algorithm it is compared to some famous systems (MS Word2000, Aspell, winEdt). The results show that our approach is superior to the alternative approaches.

  16. Additional safety risk to exceptionally approved drugs in Europe?

    Science.gov (United States)

    Arnardottir, Arna H; Haaijer-Ruskamp, Flora M; Straus, Sabine M J; Eichler, Hans-Georg; de Graeff, Pieter A; Mol, Peter G M

    2011-09-01

    Regulatory requirements for new drugs have increased. Special approval procedures with priority assessment are possible for drugs with clear 'unmet medical need'. We question whether these Exceptional Circumstances (EC) or Conditional Approval (CA) procedures have led to a higher probability of serious safety issues. A retrospective cohort study was performed of new drugs approved in Europe between 1999 and 2009. The determinant was EC/CA vs. standard procedure approval. Outcome variables were frequency and timing of a first Direct Healthcare Professional Communication (DHPC). An association between approval procedure and the time from market approval to DHPC was assessed using Kaplan-Meyer survival analysis and Cox-regression to correct for covariates. In total 289 new drugs were approved. Forty-six (16.4%) were approved under EC or CA, of which seven received a DHPC (15%). This was similar to the standard approval drugs (243), of which 33 received one or more DHPC (14%, P= 0.77). The probability of acquiring a DHPC for standard approval drugs vs. EC/CA drugs during 11-year follow-up is 22% (95% CI 14%, 29%) and 26% (95% CI 8%, 44%), respectively (log-rank P= 0.726). This difference remained not significant in the Cox-regression model: hazard ratio 0.94 (95% CI 0.40, 2.20). Only drug type was identified as a confounding covariate. The EC/CA procedure is not associated with a higher probability of DHPCs despite limited clinical development data. These data do not support the view that early drug approval increases the risk of serious safety issues emerging after market approval. © 2011 The Authors. British Journal of Clinical Pharmacology © 2011 The British Pharmacological Society.

  17. Writing effective consultation letters: 12 tips for teachers.

    Science.gov (United States)

    Keely, Erin; Dojeiji, Suzan; Myers, Kathryn

    2002-11-01

    Written correspondence is the standard mode of communication between healthcare providers. Despite the importance of this skill and increased emphasis on ambulatory care, communication skills and professionalism in training programs, there has been very little written on the teaching and evaluation of consultation letter writing. Consultation letter writing is an essential skill that cannot be learned simply by reading others' letters and should be taught in a formal manner. This article describes the authors' experience in teaching the skill of writing effective consultation letters to residents and describes strategies for evaluating this skill.

  18. 50 CFR 216.256 - Applications for Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... in the Gulf of Mexico § 216.256 Applications for Letters of Authorization. To incidentally...

  19. Pembrolizumab: first global approval.

    Science.gov (United States)

    Poole, Raewyn M

    2014-10-01

    Pembrolizumab [Keytruda(®) (US)], a humanized monoclonal antibody against the programmed death receptor-1 (PD-1) protein, has been developed by Merck & Co for the treatment of cancer. Pembrolizumab has received its first global approval for the treatment of advanced, unresectable or metastatic malignant melanoma in the US, for use in patients with disease progression after prior treatment with ipilimumab and, for BRAF V600 mutation-positive patients, a BRAF inhibitor. It is the first anti-PD-1 therapy to receive regulatory approval in the US, and is currently under regulatory review in the EU. This article summarizes the milestones in the development of pembrolizumab leading to this first approval for the treatment of malignant melanoma.

  20. Pomalidomide: first global approval.

    Science.gov (United States)

    Elkinson, Shelley; McCormack, Paul L

    2013-05-01

    Pomalidomide (Pomalyst(®)) is a small molecule analogue of thalidomide under development with Celgene Corporation for the oral treatment of haematological and connective tissue diseases. Pomalidomide has been approved in the USA and is awaiting approval in the EU for use with low-dose dexamethasone for the treatment of relapsed and refractory multiple myeloma that has progressed following at least two prior therapies, including lenalidomide and bortezomib. The efficacy and safety of pomalidomide as monotherapy in patients with relapsed and refractory multiple myeloma has also been evaluated in a phase III trial. The agent is in phase III clinical development for the treatment of myelofibrosis and in phase II development for systemic sclerosis. Pomalidomide is also being investigated in patients with amyloidosis, prostate cancer, small cell lung cancer, pancreatic cancer, graft-versus-host disease, and Waldenstrom's macroglobulinaemia. This article summarizes the milestones in the development of pomalidomide leading to this first global approval for relapsed and refractory multiple myeloma.

  1. Apremilast: first global approval.

    Science.gov (United States)

    Poole, Raewyn M; Ballantyne, Anita D

    2014-05-01

    Apremilast (Otezla(®)), an oral small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4), is under development with Celgene Corporation for the treatment of psoriatic arthritis, psoriasis, ankylosing spondylitis, Behçet's syndrome, atopic dermatitis, and rheumatoid arthritis. Apremilast is indicated for the treatment of active psoriatic arthritis in adults. Apremilast has received its first global approval for this indication in the USA. Regulatory submissions for approval in this indication are under review in Canada and Europe. Regulatory filings have also been submitted for apremilast in the treatment of plaque psoriasis in the USA and Europe. This article summarizes the milestones in the development of apremilast leading to its first approval for the treatment of psoriatic arthritis.

  2. Six steps to fast-track insurance approval for bariatric surgery.

    Science.gov (United States)

    Frezza, Eldo E

    2006-05-01

    Most of the health-insurers approve bariatric surgery for patients according to the NIH standards, while others only approve the surgery if the patient has a BMI >50. Therefore, it is important for the physician to know and carefully follow the various criteria of different insurance companies. We suggest 6 steps to fast-track insurance approval: 1) a multidisciplinary team; 2) 6-month diet; 3) comprehensive medical evaluation; 4) flexibility and consistency; 5) analysis of each patient indication; 6) quality of cost-effectiveness and long-term monitoring and benefits. In the event that an insurance company rejects the request for surgery, a blueprint of an appeal letter is very important. The appeal letter should stress the indications and benefits of surgery for your patients. Insurance company criteria may differ from the NIH guidelines. Irrespective of this, the steps outlined will help speed the insurance approval process and reduce paperwork and confusion. Most often, rejections stem from letters that were not written clearly or that lacked one or more of the elements delineated above. If the surgeon follows the 6 steps described, he/she should meet less disappointment, as in our experience that went from 50% to 90% success because of better communication with insurance and more appropriate paperwork.

  3. Open Letter to the European Commission

    DEFF Research Database (Denmark)

    Savin, Andrej; Schwemer, Sebastian Felix

    2016-01-01

    to the information society. A key component of this acquis is the prohibition of general monitoring obligations to the benefit of providers of intermediary services. It is a means to achieve at least two central objectives: the encouragement of innovation as well as the protection of fundamental rights of all...... Internet users, namely the rights protected by Articles 8 and 11 of the European Convention of Human Rights. Yet, the proposed Copyright Directive, in particular, seems to negatively affect both the domain and effect of Article 15 of the E-commerce Directive. The signatories of this open letter therefore...... urge the European Commission to take into account the human rights dimension of Article 15 of the E-commerce Directive, as made explicit by the Court of the Justice of the European Union, and to make sure its implications are carefully examined across sectors. Authors: Sophie Stalla-Bourdillon Eleonora...

  4. Original Sin in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    孙婷

    2012-01-01

    The Scarlet Letter,a representative work of Nathaniel Hawthorne,is a classical novel in American literature of 19th century.It vividly portrays people's life which was greatly influenced by Puritanism and Calvinism.And the author Nathaniel Hawthorne,who lived in that er-a,is also inevitably influenced by these mainstream thoughts.He ex-pressed his black romanticism,black view of human nature and original sin theory in almost each of his work.In his masterpiece,the Scarlet Let-ter,one important theme is original sin.This essay will first analyze where the original sin theory stems from and how it's developed by Hawthorne,and secondly will study how this theory influences the plot and major characters.

  5. NEESPI focus issues in Environmental Research Letters

    Science.gov (United States)

    Norman, Julian; Groisman, Pavel; Soja, Amber J.

    2010-05-01

    In 2007 and 2009 Environmental Research Letters published focus issues (edited by Pavel Groisman and Amber J Soja) made up of work carried out by NEESPI participants. Here, we present the content of those focus issues as an invaluable resource for researchers working in the NEESPI study area. The first of the two issues, published in 2007 with title 'Northern Hemisphere High Latitude Climate and Environmental Change', presents a diverse collection of articles that are assembled into five groups devoted to studies of climate and hydrology, land cover and land use, the biogeochemical cycle and its feedbacks, the cryosphere, and human dimensions. The second issue, published in 2009, with title 'Climatic and Environmental Change in Northern Eurasia' presents diverse, assorted studies of different aspects of contemporary change, representing the diversity of climates and ecosystems across Northern Eurasia.

  6. Resource Letter BH-2: Black Holes

    CERN Document Server

    Gallo, Elena

    2008-01-01

    This resource letter is designed to guide students, educators, and researchers through (some of) the literature on black holes. Both the physics and astrophysics of black holes are discussed. Breadth has been emphasized over depth, and review articles over primary sources. We include resources ranging from non-technical discussions appropriate for broad audiences to technical reviews of current research. Topics addressed include classification of stationary solutions, perturbations and stability of black holes, numerical simulations, collisions, the production of gravity waves, black hole thermodynamics and Hawking radiation, quantum treatments of black holes, black holes in both higher and lower dimensions, and connections to nuclear and condensed matter physics. On the astronomical end, we also cover the physics of gas accretion onto black holes, relativistic jets, gravitationally red-shifted emission lines, evidence for stellar-mass black holes in binary systems and super-massive black holes at the centers...

  7. Boscovich: scientist and man of letters

    Science.gov (United States)

    Proverbio, E.

    Ruggiero Giuseppe Boscovich (1711-1781) is known as one of the most important scientists of the second half of XVIII century, but he was active also as a man of letters, especially through an abundant production of poems in Latin verse. We try to interpret these two, apparently antinomic, aspects of his character in the framework of the culture of his epoch, in which science and literary productions were not considered as two separate or opposite fields, but only two different aspects of human knowledge. In particular we review the field of his poetic production in which this fundamental unity of knowledge is most evident, namely his poems with didactic-scientific subjects, which are examples of high-level popularization of the latest progresses in science (in particular astronomy and Newtonian physics) by means of elegant Latin verse.

  8. A Key to the Art of Letters

    DEFF Research Database (Denmark)

    Jensen-Rix, Robert William

    2008-01-01

    The article examines A. Lane's grammar A Key to the Art of Letters and its contexts. Symbolically published at the threshold to the eighteenth century, Lane presents an unusually bold plan to make English a world language. Although Lane's book holds a key position in the development of English...... grammatical theory, there has been no comprehensive study of its innovative methods and radical proposals for a new national curriculum. Its challenge to Latin and French is analyzed in a historical perspective, and the impact of Lane's ideas during the eighteenth century is traced. The article shows...... that Lane is the first to use English as the basis for writing universal grammar, as part of his strategy to promote English as a universal code for learning and science...

  9. 77 FR 25522 - Self-Regulatory Organizations; ICE Clear Credit LLC; Order Approving Proposed Rule Change to...

    Science.gov (United States)

    2012-04-30

    ... was published for comment in the Federal Register on March 12, 2012.\\2\\ The Commission received no comment letters. For the reasons discussed below, the Commission is granting approval of the proposed rule... versa. Under the current ICC Rules (by way of the incorporated ISDA Credit Derivatives Definitions), and...

  10. 77 FR 26066 - Self-Regulatory Organizations; ICE Clear Europe Limited; Order Approving Proposed Rule Change to...

    Science.gov (United States)

    2012-05-02

    ... proposed rule change was published for comment in the Federal Register on March 19, 2012.\\2\\ The Commission received no comment letters. For the reasons discussed below, the Commission is granting approval of the... current ICE Clear Europe Rules (by way of the incorporated ISDA Credit Derivatives Definitions), and...

  11. 75 FR 59299 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Amending Its...

    Science.gov (United States)

    2010-09-27

    ... Commission received no comment letters on the proposal. This order approves the proposed rule change. \\1\\ 15... combination with SFTI connections and optic connections to outside access centers and within the data center. The SFTI and optic connections are not related to the co-location services. Amex represented that...

  12. FDA Approval for Imiquimod

    Science.gov (United States)

    On July 15, 2004, the U.S. Food and Drug Administration (FDA) announced the approval of a new indication for Aldara® (imiquimod) topical cream for the treatment of superficial basal cell carcinoma (sBCC), a type of skin cancer.

  13. Correction: An Indicator of Media Credibility

    Directory of Open Access Journals (Sweden)

    Gordana Vilović

    2010-12-01

    Full Text Available The regularity of publishing corrections, clarifi cations, and letters to the editor, entail a high level of respect among the media for their audiences as they signify accountability and media credibility.This study began on the general assumption that the Croatian media is reluctant to publish corrections regularly, projecting an image that errors simply do not occur. Certainly errorless reporting is impossible due to fact that journalism is a profession prone to human error. Therefore, this study has enacted a content analysis methodology to follow the four primary Croatian daily newspapers, Jutarnji list, Večernji list, 24 sata and Vjesnik, for the period between May 6 and 30, 2010. The primary conclusion is that Croatian newspaper editors are hesitant to publish corrections if they are not under pressure from the Media Law.

  14. 14 CFR 136.3 - Letters of Authorization.

    Science.gov (United States)

    2010-01-01

    ...) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS COMMERCIAL AIR TOURS AND NATIONAL PARKS AIR TOUR MANAGEMENT National Air Tour Safety Standards § 136.3 Letters of Authorization. Operators subject to this subpart who have Letters of Authorization may use the...

  15. Open Letter to Religious Leaders about Sex Education

    Science.gov (United States)

    American Journal of Sexuality Education, 2011

    2011-01-01

    The "Open Letter to Religious Leaders about Sex Education" reinforces scriptural and theological commitments to truth-telling in calling for "full and honest education about sexual and reproductive health." This "Open Letter" was published in 2002, at about the midpoint of a decade-long federal government commitment to…

  16. Letter Position Coding Across Modalities: The Case of Braille Readers

    Science.gov (United States)

    Perea, Manuel; García-Chamorro, Cristina; Martín-Suesta, Miguel; Gómez, Pablo

    2012-01-01

    Background The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. Methodology Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. Principal Findings We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. Conclusions The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality) occur at a relatively late, abstract locus. PMID:23071522

  17. Letter position coding across modalities: the case of Braille readers.

    Directory of Open Access Journals (Sweden)

    Manuel Perea

    Full Text Available BACKGROUND: The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. METHODOLOGY: Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. PRINCIPAL FINDINGS: We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. CONCLUSIONS: The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality occur at a relatively late, abstract locus.

  18. Editorial: acceptance criteria and editorial procedures for Optics Letters.

    Science.gov (United States)

    Zhang, Xi-Cheng; Andersen, Peter E; Justus, Brian L; Galtarossa, Andrea

    2014-09-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning the decision-making process will increase understanding as well as acceptance of our criteria and procedures.

  19. Analyzing International Letters in a Business Communication Class.

    Science.gov (United States)

    Devet, Bonnie

    1998-01-01

    Shows how students can use persuasive principles of communication (format and writer's purpose) and of classical rhetoric (organization, ethos, pathos, logos, and style) to improve their ability to analyze business letters. Shows how applying these principles to the analysis of business letters from other countries helps students write better and…

  20. 48 CFR 432.406 - Letters of credit.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Letters of credit. 432.406... REQUIREMENTS CONTRACT FINANCING Advance Payments for Non-Commercial Items 432.406 Letters of credit. The HCA is... of credit. ...

  1. Letters to Our Forebears: Reconnecting Generations through Writing.

    Science.gov (United States)

    Okawa, Gail Y.

    2003-01-01

    Proposes that students writing public letters to their forebears might provide a reminder of how individuals and communities can learn from the experience of their foremothers and forefathers. Includes the author's letter to her grandfather, who was imprisoned in internment camps for Japanese Americans during World War II. (PM)

  2. RESEARCH ON THE LETTER TO THE GALATIANS: 2000-2010

    African Journals Online (AJOL)

    an overall picture of developments pertaining to the research on the letter. Accordingly, I have ..... that the letter shows that the classical experiences of a democratic city ...... The Psalms in the New Testament (New York/London: T&T Clark), pp.

  3. An Approach to the Humanity of the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    Du Feng; Wang qingping

    2009-01-01

    "The Scarlet Letter"is Hawthorne's realist representative.In his masterpiece the Scarlet letter.Hawthorne tells us that all human beings are combination of goodness and evil.As human nature changes between goodness and evil,the science mastered by human beings may bring happiness or pains.

  4. Persuasive Elements of 100 Successful Magazine Query Letters.

    Science.gov (United States)

    Jolliffe, Lee

    Building from scholarly works on persuasion and compliance-gaining, a study investigated magazine query letters that attempt to persuade an editor to buy the article offered, examining what message elements make them successful. Forty magazine editors provided copies of 100 recently accepted magazine query letters, which were compared with 50…

  5. 5 CFR 536.404 - Issuance of employee letters.

    Science.gov (United States)

    2010-01-01

    ... AND PAY RETENTION Appeals and Miscellaneous Provisions § 536.404 Issuance of employee letters. When an employee is entitled to grade and/or pay retention, the employing agency shall give to the employee, with a... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Issuance of employee letters. 536.404...

  6. Teaching Braille Letters, Numerals, Punctuation, and Contractions to Sighted Individuals

    Science.gov (United States)

    Putnam, Brittany C.; Tiger, Jeffrey H.

    2015-01-01

    Braille-character recognition is one of the foundational skills required for teachers of braille. Prior research has evaluated computer programming for teaching braille-to-print letter relations (e.g., Scheithauer & Tiger, 2012). In the current study, we developed a program (the Visual Braille Trainer) to teach not only letters but also…

  7. Transhuman Education? Sloterdijk's Reading of Heidegger's "Letter on Humanism"

    Science.gov (United States)

    Long, Fiachra

    2017-01-01

    Peter Sloterdijk presented a reading of Heidegger's "Letter on Humanism" at a conference held at Elmau in 1999. Reinterpreting the meaning of humanism in the light of Heidegger's "Letter," Sloterdijk focused his presentation on the need to redefine education as a form of genetic "taming" and proposed what seemed to be…

  8. Pseudo-synesthesia through reading books with colored letters

    NARCIS (Netherlands)

    Colizoli, O.; Murre, J.M.J.; Rouw, R.

    2012-01-01

    Background Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter ‘a’ always appears as light blue). In this study, we examine whether traits

  9. Sidebearings analysis of alphabet letters with complex shape

    Directory of Open Access Journals (Sweden)

    Bojan Banjanin

    2014-12-01

    Full Text Available Defining inter-letter space is important part of typeface designing process. The purpose of defining the letter space is to make them visually equally distant from each other within words, sentences and paragraphs creating an even value of grey, without darker or lighter areas. Different approaches for determining letter space were developed in order to facilitate this demanding process. Miguel Sousa (2006 and Walter Tracy (2003 proposes their spacing methods and in paper of De Melo Vargas (2007 and our previous work (Banjanin & Nedeljković, 2014 these methods were tested. The problems occur when defining space around letters a, f, g, s, t, z, and S, for which neither Sousa nor Tracy propose any kind of guidelines (except visual. The aim of this paper is to measure and analyse spacing values for these letters and to see if there is some kind of “formula” or some kind of guidelines which will broaden existing methods in more accurate way. We measured left and right sidebearings of these 7 problematic letters and established additional guidelines for defining letter space of those letters more accurately.

  10. Character Invention in the Letters of Maimie Pinzer.

    Science.gov (United States)

    Carlson, A. Cheree

    1995-01-01

    Presents a case study of autobiographical letters written by a turn-of-the-century prostitute to a Boston matron. Shows how, in creating a narrative of her life, the author of the letters uses several rhetorical strategies to recreate her character to persuade her audience (and herself) that she is worthy of respect. (SR)

  11. Patient information letters on nutrition: development and implementation.

    NARCIS (Netherlands)

    Binsbergen, J.J. van; Drenthen, A.J.

    2003-01-01

    BACKGROUND: In 1998 the Dutch College of General Practitioners (NHG) began developing patient information letters (PILs), based on the practice guidelines for family physicians (FPs) (NHG standards). Five nutritional guidance letters have since been developed with the Dutch Nutrition Center. METHODS

  12. Teaching Braille Letters, Numerals, Punctuation, and Contractions to Sighted Individuals

    Science.gov (United States)

    Putnam, Brittany C.; Tiger, Jeffrey H.

    2015-01-01

    Braille-character recognition is one of the foundational skills required for teachers of braille. Prior research has evaluated computer programming for teaching braille-to-print letter relations (e.g., Scheithauer & Tiger, 2012). In the current study, we developed a program (the Visual Braille Trainer) to teach not only letters but also…

  13. Motion Detection, Letter Position Encoding, and Single Word Reading.

    Science.gov (United States)

    Cornelissen, P. L.; Hansen, P. C.

    1998-01-01

    A study involving 48 undergraduates found a link between motion detection and letter-position encoding and a positive relationship, albeit a nonlinear one, between motion detection threshold and the likelihood of making letter errors. This result held when age, IQ, reading age, and phonological awareness were taken into account. (CR)

  14. Editorial: acceptance criteria and editorial procedures for Optics Letters

    DEFF Research Database (Denmark)

    Zhang, Xi-Cheng; Andersen, Peter E.; Justus, Brian L.

    2014-01-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning...

  15. Editorial: acceptance criteria and editorial procedures for Optics Letters.

    OpenAIRE

    Zhang, Xi-Cheng; Andersen, Peter E.; Justus, Brian L.; Galtarossa, Andrea

    2014-01-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning the decision-making process will increase understanding as well as acceptance of our criteria and procedures.

  16. Open Letter to Religious Leaders about Sex Education

    Science.gov (United States)

    American Journal of Sexuality Education, 2011

    2011-01-01

    The "Open Letter to Religious Leaders about Sex Education" reinforces scriptural and theological commitments to truth-telling in calling for "full and honest education about sexual and reproductive health." This "Open Letter" was published in 2002, at about the midpoint of a decade-long federal government commitment to…

  17. [The letters of Hermann Rorschach to his brother].

    Science.gov (United States)

    Signer, Rita; Müller, Christian

    2005-01-01

    Hermann Rorschach, brilliant creator of the projective test called after him, worked from the beginning to the middle of 1914 in a sanatorium near Moscow. Recently discovered letters to his brother Paul reveal his motives for abandoning his initial plan to settle in Russia. Apparently the impossibility of scientific work was of great importance. Additional letters complement our knowledge of Rorschach's personality.

  18. 50 CFR 216.106 - Letter of Authorization.

    Science.gov (United States)

    2010-10-01

    .... citizens, is required to conduct activities pursuant to any regulations established under § 216.105. Requests for Letters of Authorization shall be submitted to the Director, Office of Protected Resources... request. (d) Notice of issuance of all Letters of Authorization will be published in the Federal Register...

  19. Letters to a Young Baller: Exploring Epistolary Criticism

    Science.gov (United States)

    Chawansky, Megan

    2010-01-01

    This article explores the possibilities of epistolary criticism within the realm of sport studies and aspires to encourage scholars to consider the use of non-traditional sport memorabilia and source materials when telling emotive stories about sport and sport practices. The use of letters and the letter-writing format to tell a personal narrative…

  20. 12 CFR 614.4720 - Letters of credit.

    Science.gov (United States)

    2010-01-01

    ... Commercial Code, or the Uniform Customs and Practice for Documentary Credits, to or on behalf of its customers. In addition, as a matter of sound banking practice, letters of credit shall be issued in... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Letters of credit. 614.4720 Section 614.4720...

  1. Overt use of a tactile-kinesthetic strategy shifts to covert processing in rehabilitation of letter-by-letter reading.

    Science.gov (United States)

    Lott, Susan Nitzberg; Carney, Aimee Syms; Glezer, Laurie S; Friedman, Rhonda B

    2010-11-01

    BACKGROUND: Letter-by-letter readers identify each letter of the word they are reading serially in left to right order before recognizing the word. When their letter naming is also impaired, letter-by-letter reading is inaccurate and can render even single word reading very poor. Tactile and/or kinesthetic strategies have been reported to improve reading in these patients, but only under certain conditions or for a limited set of stimuli. AIMS: The primary aim of the current study was to determine whether a tactile/kinesthetic treatment could significantly improve reading specifically under normal reading conditions, i.e. reading untrained words presented in free vision and read without overt use of the strategy. METHODS #ENTITYSTARTX00026; PROCEDURES: Three chronic letter-by-letter readers participated in a tactile/kinesthetic treatment aimed at first improving letter naming accuracy (phase 1) and then letter-by-letter reading speed (phase 2). In a multiple case series design, accuracy and speed of reading untrained words without overt use of the trained tactile/kinesthetic strategy was assessed before phase 1, after phase 1 and again after phase 2. OUTCOMES #ENTITYSTARTX00026; RESULTS: All three patients significantly improved both their speed and accuracy reading untrained words without overt use of the trained tactile/kinesthetic strategy. All three patients required the additional practice in phase 2 to achieve significant improvement. Treatment did not target sentence level reading, yet two of the three patients became so adept that they could read entire sentences. CONCLUSIONS: This study replicates previous findings on the efficacy of tactile/kinesthetic treatment for letter-by-letter readers with poor letter naming. It further demonstrates that this treatment can alter cognitive processing such that words never specifically trained can be read in free vision without overtly using the trained strategy. The data suggest that an important element in achieving

  2. Professor Eric G.L. Bywaters, Acute Kidney Injury and the "forgotten" letter.

    Science.gov (United States)

    Almond, Michael

    2016-02-01

    The Bywaters seminal 1941 British Medical Journal paper on the crush syndrome was important both for its written content and for using a photomicrograph demonstrating pigmented casts in the renal tubules. He appeared to be reporting the first cases of renal failure secondary to crushing injuries. Most at this point would have been content yet Bywaters demonstrated both determination and humility by publishing a letter in the BMJ 4 months later. This letter, now almost forgotten and rarely referenced, significantly corrected his original paper. He identified that descriptions of the syndrome had been made before, not least by German pathologists in World War 1. The letter recognised various pathologists and surgeons, Colmers (1909) reporting on casualties from the Messina earthquake suffering from acute pressure necrosis and Frankenthal (1916) describing soldiers who had been buried in the trenches showing oedema, bloody urine and post mortem ischaemic muscle necrosis. Others were credited as describing similar cases in inaccessible journals or in "inaugural dissertations". Hackradt (1917) described injuries from burial with oedema of the leg and bloody urine containing albumin and casts, necropsy showed muscle necrosis and tubular degeneration in the kidneys with blood casts and Lewin (1919) described 3 similar cases. Bywaters subsequently credits Minami (1923) a Japanese dermatologist working in Germany for summarizing the literature and providing a description that tallied exactly with his own. Finally Bywaters puzzles why the standard textbooks on war surgery available in Great Britain and the U.S.A. in 1941 make no mention of this entity.

  3. Digit and letter alexia in carbon monoxide poisoning

    Institute of Scientific and Technical Information of China (English)

    Qingyu Shen; Xiaoming Rong; Rui Pan; Ying Peng; Wei Peng; Yamei Tang

    2012-01-01

    This study examined a 24-year-old patient with delayed encephalopathy, who was admitted to hospital with complaints of headache and visual impairment 1 week after acute carbon monoxide poisoning. The results of a visual field assessment, electroencephalography and head magnetic resonance imaging indicated damage to the cerebral cortex. After a 2-week treatment period, the patient had recovered from the visual impairment, but exhibited digit- and letter-reading difficulty. The Chinese aphasia battery and the number and letter battery supplement were conducted. The results revealed that the patient exhibited digit and letter alexia, while the ability to read Chinese characters was preserved. In contrast, the patient exhibited a deficit in Chinese character writing, while number and letter writing remained intact. Following treatment, reading and writing ability was improved and electroencephalographic abnormalities were ameliorated. Overall, our experimental findings demonstrated that delayed encephalopathy following acute carbon monoxide poisoning was characterized by digit and letter alexia.

  4. Automatic adverse drug events detection using letters to the editor.

    Science.gov (United States)

    Yang, Chao; Srinivasan, Padmini; Polgreen, Philip M

    2012-01-01

    We present and test the intuition that letters to the editor in journals carry early signals of adverse drug events (ADEs). Surprisingly these letters have not yet been exploited for automatic ADE detection unlike for example, clinical records and PubMed. Part of the challenge is that it is not easy to access the full-text of letters (for the most part these do not appear in PubMed). Also letters are likely underrated in comparison with full articles. Besides demonstrating that this intuition holds we contribute techniques for post market drug surveillance. Specifically, we test an automatic approach for ADE detection from letters using off-the-shelf machine learning tools. We also involve natural language processing for feature definitions. Overall we achieve high accuracy in our experiments and our method also works well on a second new test set. Our results encourage us to further pursue this line of research.

  5. Remarks about interaction, genre textual and text planin personal letters

    Directory of Open Access Journals (Sweden)

    Marise Adriana Mamede Galvão

    2013-12-01

    Full Text Available This article presents a discussion concerning interaction, genre and text plan in personal letters from textual and interactional perspectives. The study is based on notions of verbal interaction, genre, and text plan, aiming to describe, analyze and interpret linguistic and textual evidences through personal letters. The research corpus is comprised of a letter written by Luis da Câmara Cascudo, addressed to Mário de Andrade, selected from a set of correspondences gathered into one volume under the title Cascudo and Mário de Andrade, Letters, 1924-1944. This study is carried out using a qualitative approach, focusing on social practices used by interactants to achieve specific goals through letters. Thus, reflections on this object have highlighted it as a form of sociability and involvement among people who use a genre in interactions and construct texts through fixed and occasional plans.

  6. Episodic effects on the visual comparison of letters in words.

    Science.gov (United States)

    Marmurek, H H

    1992-11-01

    In two experiments, subjects compared the identity of either the first letters of displays or all the letters in displays. Words yielded faster decisions than did pseudowords (pronounceable items derived by changing a vowel in a word) only when entire displays were compared. In a training phase run before the comparison task, subjects had written down either the first letters or entire displays. Relative to items that had not appeared in the training phase, prior experience at writing entire displays facilitated same decisions about entire displays and interfered with different decisions about entire displays. Prior experiences did not moderate the processing of first-letter identities. It was concluded that episodic effects arise from the interaction of higher order information underlying lexical encoding. Prelexical processing of letters is not sensitive to episodic effects.

  7. 42 CFR 431.992 - Corrective action plan.

    Science.gov (United States)

    2010-10-01

    ... Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Estimating Improper Payments in Medicaid and CHIP § 431.992 Corrective action plan. (a) The State agency must develop a separate corrective action plan for Medicaid and CHIP, which is not required to be approved by...

  8. Peer assessment of outpatient consultation letters – feasibility and satisfaction

    Directory of Open Access Journals (Sweden)

    Dojeiji Suzan

    2007-05-01

    Full Text Available Abstract Background Written correspondence is one of the most important forms of communication between health care providers, yet there is little feedback provided to specialists. The objective of this study was to determine the feasibility and satisfaction of a peer assessment program on consultation letters and to determine inter-rater reliability between family physicians and specialists. Methods A rating scale of nine 5-point Likert scale items including specific content, style items, education value of the letter and an overall rating was developed from a previous validated tool. Nine Internal Medicine specialists/subspecialists from two tertiary care centres submitted 10 letters with patient and physician identifiers removed. Two Internal Medicine specialists, and 2 family physicians from the other centre rated each letter (to protect writer anonymity. A satisfaction survey was sent to each writer and rater after collation of the results. A follow-up survey was sent 6–8 months later. Results There was a high degree of satisfaction with the process and feedback. The rating scale information was felt to be useful and appropriate for evaluating the quality of consultation letters by 6/7 writers. 5/7 seven writers felt that the feedback they received resulted in immediate changes to their letters. Six months later, 6/9 writers indicated they had maintained changes in their letters. Raters rank ordered letters similarly (Cronbach's alpha 0.57–0.84 but mean scores were highly variant. At site 1 there were significant differences in scoring brevity (p Conclusion Most participants found peer assessment of letters feasible and beneficial and longstanding changes occurred in some individuals. Family physicians and specialists appear to have different expectations on some items. Further studies on reliability and validity, with a larger sample, are required before high stakes professional assessments include consultation letters.

  9. The Contributions of Phonological Awareness and Letter-Name Knowledge to Letter-Sound Acquisition--A Cross-Classified Multilevel Model Approach

    Science.gov (United States)

    Kim, Young-Suk; Petscher, Yaacov; Foorman, Barbara R.; Zhou, Chengfu

    2010-01-01

    In the present study, we investigated critical factors in letter-sound acquisition (i.e., letter-name knowledge and phonological awareness) with data from 653 English-speaking kindergartners in the beginning of the year. We examined (a) the contribution of phonological awareness to facilitating letter-sound acquisition from letter names and (b)…

  10. FDA Approvals - Cancer Currents Blog

    Science.gov (United States)

    A catalog of posts from NCI’s Cancer Currents blog on new Food and Drug Administration approvals of cancer drugs. All posts include summaries of the evidence to support the new approvals and what they mean for patients.

  11. Drugs Approved for Skin Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Skin Cancer This page lists cancer drugs approved by the Food and Drug Administration (FDA) for skin cancer, including drugs for basal cell carcinoma, melanoma, and ...

  12. Detecting letters and words in prose passages: a test of alternative theoretical accounts of the missing letter effect.

    Science.gov (United States)

    Healy, Alice F; Cunningham, Thomas F

    2014-01-01

    College students searched for either h or the in prose passages in which every h occurred in the test word the. In Experiment 1, passage versions differed in that the critical noun phrases were either the alone (i.e., in citation form as a noun referring to itself) or "the definite article." Many more detection errors occurred for letter than word target items, especially with "the definite article." In Experiment 2, passage versions differed in that a given noun phrase containing the test word the occurred as a subject in one version and an object in the other. Again, many more detection errors occurred when the target item was the letter h than when it was the letter sequence the. Also, with letter but not letter sequence targets, more detection errors occurred for object than subject noun phrases. In Experiment 3, passages were presented either in regular format or with all capital letters. Students made more detection errors with the regular than with the capitals format, many more errors occurred when participants searched for letters than for letter sequences, and the effect of target item was larger with regular than with capitals format. These findings suggest that accounts of detection errors in reading must include the influence of unitization and processing time or attentional allocation.

  13. Crowded letter and crowded picture logMAR acuity in children with amblyopia: a quantitative comparison.

    Science.gov (United States)

    O'Boyle, Cathy; Chen, Sean I; Little, Julie-Anne

    2017-04-01

    Clinically, picture acuity tests are thought to overestimate visual acuity (VA) compared with letter tests, but this has not been systematically investigated in children with amblyopia. This study compared VA measurements with the LogMAR Crowded Kay Picture test to the LogMAR Crowded Keeler Letter acuity test in a group of young children with amblyopia. 58 children (34 male) with amblyopia (22 anisometropic, 18 strabismic and 18 with both strabismic/anisometropic amblyopia) aged 4-6 years (mean=68.7, range=48-83 months) underwent VA measurements. VA chart testing order was randomised, but the amblyopic eye was tested before the fellow eye. All participants wore up-to-date refractive correction. The Kay Picture test significantly overestimated VA by 0.098 logMAR (95% limits of agreement (LOA), 0.13) in the amblyopic eye and 0.088 logMAR (95% LOA, 0.13) in the fellow eye, respectively (pamblyopia on VA results (p>0.23). For both the amblyopic and fellow eyes, Bland-Altman plots demonstrated a systematic and predictable difference between Kay Picture and Keeler Letter charts across the range of acuities tested (Keeler acuity: amblyopic eye 0.75 to -0.05 logMAR; fellow eye 0.45 to -0.15 logMAR). Linear regression analysis (pamblyopia. Due to the predictable difference found between both crowded logMAR acuity tests, it is reasonable to adjust Kay Picture acuity thresholds by +0.10 logMAR to compute expected Keeler Letter acuity scores. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. Pitolisant: First Global Approval.

    Science.gov (United States)

    Syed, Yahiya Y

    2016-09-01

    Pitolisant (Wakix™) is an inverse agonist of the histamine H3 receptor that is being developed by Bioproject. Oral pitolisant is approved in the EU for the treatment of narcolepsy with or without cataplexy in adults. Pitolisant has received a Temporary Authorization of Use in France for this indication in case of treatment failure, intolerance or contraindication to currently available treatment. Pitolisant has orphan drug designation in the EU and the USA. In the pivotal HARMONY I trial, pitolisant significantly decreased excessive daytime sleepiness versus placebo in adults with narcolepsy with or without cataplexy (primary endpoint). Pitolisant also significantly decreased cataplexy rate versus placebo in these patients. This article summarizes the milestones in the development of pitolisant leading to this first approval for narcolepsy.

  15. Linaclotide: first global approval.

    Science.gov (United States)

    McWilliams, Vanessa; Whiteside, Glenn; McKeage, Kate

    2012-11-12

    Linaclotide is a once-daily, orally administered, first-in-class agonist of guanylate cyclase-C that is minimally absorbed. It is being developed to treat gastrointestinal disorders by Ironwood Pharmaceuticals and its partners, Forest Laboratories (North America), Almirall (Europe) and Astellas Pharma (Asia-Pacific). Linaclotide has received its first global approval in the US for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC), and a marketing submission has been filed in the EU for IBS-C. This article summarizes the milestones in the development of linaclotide leading to this first approval for IBS-C and CIC. This profile has been extracted and modified from the Adis R&D Insight drug pipeline database. Adis R&D Insight tracks drug development worldwide through the entire development process, from discovery, through pre-clinical and clinical studies to market launch.

  16. Rucaparib: First Global Approval.

    Science.gov (United States)

    Syed, Yahiya Y

    2017-04-01

    Rucaparib (Rubraca™) is an oral, small molecule, poly (ADP-ribose) polymerase inhibitor being developed by Clovis Oncology, Inc. (Boulder, CO, USA) for the treatment of solid tumours. It has been approved in the USA as monotherapy for the treatment of patients with deleterious BRCA mutation (germline and/or somatic) associated advanced ovarian cancer who have been treated with two or more chemotherapies. A marketing authorization application for rucaparib for the same indication has been submitted to the European Medicines Agency. Rucaparib is also under phase II or III investigation in ovarian, breast and prostate cancer. This article summarizes the milestones in the development of rucaparib leading to this first approval for ovarian cancer.

  17. Closure Plan for Corrective Action Unit 109: U-2bu Subsidence Crater Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Shannon Parsons

    1999-03-01

    The U-2bu subsidence crater, Corrective Action Unit 109, will be closed in accordance with the Resource Conservation and Recovery Act, the Nevada Division of Environmental Protection operational permit, and the Federal Facilities Agreement and Consent Order. The U-2bu subsidence crater is located in Area 2 of the Nevada Test Site. It was created in 1971 by an underground nuclear test with the name Miniata. The crater has a diameter of 288 meters (944 feet) and an approximate depth of 35 meters (115 feet). The subsidence crater was used as a land disposal unit for radioactive and hazardous waste from 1973 to 1988. Site disposal history is supported by memorandums, letters, and personnel who worked at the Nevada Test Site at the time of active disposal. Closure activities will include the excavation and disposal of impacted soil form the tip of the crater. Upon completion of excavation, verification samples will be collected to show that lead has been removed to concentrations be low regulatory action level. The area will then be backfilled and a soil flood diversion berm will be constructed, and certified by an independent professional engineer as to having followed the approved Closure Plan.

  18. A note on the paper: On iterations for families of asymptotically pseudocontractive mappings, Applied Mathematics Letters, 24 (2011), 33-38

    CERN Document Server

    Ofoedu, Eric U

    2010-01-01

    It is our aim in this note to give a counter example to an argument used in the proof of the main theorem of the paper: On iterations for families of asymptotically pseudocontractive mappings, Applied Mathematics Letters, 24 (2011), 33-38 by A. Rafiq; and give an alternative condition to correct the anomaly.

  19. Ipilimumab: first global approval.

    Science.gov (United States)

    Cameron, Fiona; Whiteside, Glenn; Perry, Caroline

    2011-05-28

    Ipilimumab (Yervoy®) is an anti-cytotoxic T-lymphocyte antigen (CTLA)-4 monoclonal antibody that has been approved in the US for the first- or second-line treatment of patients with malignant melanoma. In the EU, it is awaiting approval as second-line therapy for melanoma. Ipilimumab blocks the effects of the negative T-cell regulator CTLA-4, which may in turn augment T-cell responses to tumour cells. Preclinical studies have indicated that antibody blocking of CTLA-4 can lead to potent immune responses. Ipilimumab is also in development as first- and second-line therapy for prostate cancer where it has progressed to phase III clinical trials worldwide, and it is in phase II development for non-small cell lung cancer. Ipilimumab was originated by the University of California, Berkeley, in the US and subsequently licensed to Medarex, which was later acquired by Bristol-Myers Squibb. This article summarizes the milestones in the development of intravenous ipilimumab leading to this first approval. This profile has been extracted from Wolters Kluwer's R&D Insight drug pipeline database. R&D Insight tracks drug development worldwide through the entire development process, from discovery, through pre-clinical and clinical studies to market launch.

  20. Baricitinib: First Global Approval.

    Science.gov (United States)

    Markham, Anthony

    2017-03-13

    Baricitinib (Olumiant™) is an orally-administered, small-molecule, janus-associated kinase (JAK) inhibitor developed by Eli Lilly and Incyte Corporation for the treatment of rheumatoid arthritis (RA), atopic dermatitis and systemic lupus erythematosus. JAKs transduce intracellular signals from cell surface receptors for various cytokines and growth factors involved in inflammation and immune function, suggesting JAK inhibitors may be of therapeutic benefit in inflammatory conditions. In February 2017, baricitinib was approved in the EU, as monotherapy or in combination with methotrexate, for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Regulatory approval to market baricitinib as a treatment for RA has also been sought in the USA and Japan. This article summarizes the milestones in the development of baricitinib leading to this first global approval for the treatment for moderate to severe active RA in adult patients who have responded inadequately to, or are intolerant to one or more DMARDs.

  1. Evolocumab: First Global Approval.

    Science.gov (United States)

    Markham, Anthony

    2015-09-01

    Evolocumab (Repatha™) is a fully human monoclonal antibody developed by Amgen that has been approved as a treatment for hypercholesterolaemia in the EU, and is awaiting approval in the USA and Japan. It specifically binds proprotein convertase subtilisin/kexin type 9 (PCSK9)-a negative regulator of low-density lipoprotein (LDL)-receptors-thereby improving the ability of the liver to bind LDL-cholesterol (LDL-C), leading to reduced LDL-C blood levels. The drug reduces LDL-C levels in patients with hypercholesterolaemia when used as monotherapy or in conjunction with a statin. This article summarizes the milestones in the development of evolocumab leading to this approval for the treatment of adults with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia as an adjunct to diet with or without a statin and/or other lipid lowering therapies, and in adults and adolescents aged ≥12 years with homozygous familial hypercholesterolaemia in combination with other lipid lowering therapies.

  2. Corrective Action Decision Document for Corrective Action Unit 204: Storage Bunkers, Nevada Test Site, Nevada, Rev. No. 0

    Energy Technology Data Exchange (ETDEWEB)

    Robert Boehlecke

    2004-04-01

    The six bunkers included in CAU 204 were primarily used to monitor atmospheric testing or store munitions. The ''Corrective Action Investigation Plan (CAIP) for Corrective Action Unit 204: Storage Bunkers, Nevada Test Site, Nevada'' (NNSA/NV, 2002a) provides information relating to the history, planning, and scope of the investigation; therefore, it will not be repeated in this CADD. This CADD identifies potential corrective action alternatives and provides a rationale for the selection of a recommended corrective action alternative for each CAS within CAU 204. The evaluation of corrective action alternatives is based on process knowledge and the results of investigative activities conducted in accordance with the CAIP (NNSA/NV, 2002a) that was approved prior to the start of the Corrective Action Investigation (CAI). Record of Technical Change (ROTC) No. 1 to the CAIP (approval pending) documents changes to the preliminary action levels (PALs) agreed to by the Nevada Division of Environmental Protection (NDEP) and DOE, National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This ROTC specifically discusses the radiological PALs and their application to the findings of the CAU 204 corrective action investigation. The scope of this CADD consists of the following: (1) Develop corrective action objectives; (2) Identify corrective action alternative screening criteria; (3) Develop corrective action alternatives; (4) Perform detailed and comparative evaluations of corrective action alternatives in relation to corrective action objectives and screening criteria; and (5) Recommend and justify a preferred corrective action alternative for each CAS within CAU 204.

  3. 78 FR 19990 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Ohio Ambient Air Quality...

    Science.gov (United States)

    2013-04-03

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 Approval and Promulgation of Air Quality Implementation Plans; Ohio; Ohio Ambient Air Quality Standards; Correction AGENCY: Environmental Protection Agency (EPA). ACTION: Final...

  4. 76 FR 22713 - Withdrawal of Approval of New Animal Drug Applications; Phenylbutazone; Pyrantel; Tylosin...

    Science.gov (United States)

    2011-04-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Withdrawal of Approval of New Animal Drug Applications; Phenylbutazone; Pyrantel; Tylosin; Sulfamethazine; Correction AGENCY: Food and Drug Administration, HHS. ACTION...

  5. 77 FR 3213 - Approval and Promulgation of Implementation Plans; Tennessee; 110(a)(1) and (2) Infrastructure...

    Science.gov (United States)

    2012-01-23

    ... circumstances. In particular, the data and analytical tools available at the time the state develops and submits... correct errors in past actions, such as past approvals of SIP submissions.\\17\\ [[Page 3218

  6. 78 FR 26258 - Approval and Promulgation of Air Quality Implementation Plans; Illinois; Consumer Products and...

    Science.gov (United States)

    2013-05-06

    ... conditionally approved four paragraphs of 35 IAC Part 223, noting deficiencies in the state rules. The four..., submittal, IEPA has corrected the deficiencies within the prescribed time frame. We are converting...

  7. Concurrent cognitive processing and letter sequence transcription deficits in stutterers.

    Science.gov (United States)

    Webster, W G

    1990-03-01

    Previous research has indicated that men who stutter transcribe rapidly presented sequences of letters more slowly and less accurately than nonstutterer controls. Experiment 1 demonstrated that the transcription deficit is not limited to task conditions that demand concurrent monitoring and responding. This was evidenced by comparable deficits on a successive response condition that required subjects to write letters after the presentation was complete. The results of Experiment 2 indicated that the deficit is not due to a difficulty by stutterers in parsing streams of stimulus information internally. Their performance did not differentially improve when letters were grouped with brief pauses, nor with experience in transcribing preparsed letter sequences. This experiment also demonstrated that the phenomenon is generalizable to women. In related testing, stutterers were slower than controls in writing internally generated sequences of letters, those of the alphabet forwards and backwards, but not in writing the same two letters, A and B, repetitively nor in the cognitively more demanding task of writing numbers backwards by three's. These results parallel those obtained with finger tapping of same versus unique sequences by stutterers and were interpreted as being consistent with the idea that while stutterers are not generally slower motorically than nonstutterers, they experience difficulty when required to organize and carry out tasks with new multiple response transitions. The two experiments have replicated and extended, under different conditions, the earlier findings of a letter sequence transcription deficit in stutterers, but the nature of the interference still remains to be clarified.

  8. Angles of Refraction: The Letters of Mary Delany

    Directory of Open Access Journals (Sweden)

    Eleonora Chiavetta

    2014-04-01

    Full Text Available Mary Delany (1700-1788 is particularly famous for her paper-cuttings or ‘mosaicks’ based on botanical subjects. A very lively woman of fashion, she was close to Queen Charlotte and one of the Bluestocking Ladies. She left a vivid portrait of life and society in eighteenth century England and Ireland in the six volumes of her Autobiography and Letters, edited in 1861 by her descendant Lady Llanover. Her autobiography is made up of 18 letters sent to her most intimate friend, Margaret Cavendish, Duchess of Portland. The first letter is dated 1740, but in this, as in the following ones, Mrs. Delany narrates her past life to her friend, starting from the early years of her life, describing her unhappy marriage, financial difficulties as a widow, and family relationships. Along with these ‘autobiographical’ letters, other letters written by her to her sister Ann are introduced, which date to the periods of life Mrs. Delany is dealing with. The aim of this paper is to focus on the textual, linguistic and content differences between the two letter types, and analyse how the identity of Mary Delany is differently constructed and perceived in the explicit autobiographical letters addressed to the Duchess of Portland, and the ones written to her sister. 

  9. Novel Moment Features Extraction for Recognizing Handwritten Arabic Letters

    Directory of Open Access Journals (Sweden)

    Gheith Abandah

    2009-01-01

    Full Text Available Problem statement: Offline recognition of handwritten Arabic text awaits accurate recognition solutions. Most of the Arabic letters have secondary components that are important in recognizing these letters. However these components have large writing variations. We targeted enhancing the feature extraction stage in recognizing handwritten Arabic text. Approach: In this study, we proposed a novel feature extraction approach of handwritten Arabic letters. Pre-segmented letters were first partitioned into main body and secondary components. Then moment features were extracted from the whole letter as well as from the main body and the secondary components. Using multi-objective genetic algorithm, efficient feature subsets were selected. Finally, various feature subsets were evaluated according to their classification error using an SVM classifier. Results: The proposed approach improved the classification error in all cases studied. For example, the improvements of 20-feature subsets of normalized central moments and Zernike moments were 15 and 10%, respectively. Conclusion/Recommendations: Extracting and selecting statistical features from handwritten Arabic letters, their main bodies and their secondary components provided feature subsets that give higher recognition accuracies compared to the subsets of the whole letters alone.

  10. PERKEMBANGAN EMBRIO DAN LARVA IKAN LETTER SIX, Paracanthurus hepatus

    Directory of Open Access Journals (Sweden)

    Daniar Kusumawati

    2015-06-01

    Full Text Available Dalam upaya memperkaya populasi ikan letter six (Paracanthurus hepatus di alam yang telah mendekati kepunahan akibat adanya illegal fishing maka dilakukan usaha perbenihan. Kegiatan perbenihan ikan letter six memerlukan informasi awal tentang perkembangan telur dan pemeliharaan larva yang nantinya akan digunakan sebagai acuan dasar dalam menentukan pengembangan teknik pemeliharaan larva ikan letter six yang tepat. Koleksi induk ikan letter six hasil tangkapan di alam dari perairan Maluku dan Papua. Induk letter six dipelihara dalam tangki policarbonat bulat berkapasitas dua ton dengan sistem air mengalir. Selama pemeliharaan, induk letter six mampu memijah secara alami. Durasi perkembangan embrio hingga menetas memerlukan waktu 22 jam 24 menit pada suhu normal air laut 29°C. Penyerapan kuning telur optimum terjadi pada hari kedua dan maksimum terserap habis pada hari ketiga, sedangkan butir minyak terserap habis tepat pada hari ketiga. Korelasi pertumbuhan panjang dan tinggi larva mengikuti hubungan alometrik negatif di mana konstanta pertumbuhan b = 0,6629 (b < 1. Berdasarkan perkembangan larva, umur D-2 (terbentuk bintik mata mulai diberikan pakan alami berupa plankton dan pada D-3 (bukaan mulut mulai diberikan zooplankton yaitu rotifer. Dengan metode pemeliharaan ini, larva ikan letter six mati pada D-25 sehingga perlu adanya perbaikan metode pemeliharaan melalui pendekatan lingkungan maupun pakan.

  11. Parent–Child Conversations About Letters and Pictures

    Science.gov (United States)

    Robins, Sarah; Treiman, Rebecca; Rosales, Nicole; Otake, Shoko

    2014-01-01

    Learning about letters, and how they differ from pictures, is one important aspect of a young child’s print awareness. To test the hypothesis that parent speech provides children with information about these differences, we studied parent–child conversations in CHILDES (MacWhinney, 2000). We found that parents talk to their young children about letters, differentiating them from pictures, by 1–2 years of age and that some of these conversational patterns change across the preschool years in ways that emphasize important features of letters, such as their shape. We also found that children talk about letters and pictures in distinct ways, suggesting an implicit understanding of some of the differences between letters and pictures at an early age. Some differences in parent–child conversations about letters were found as a function of socioeconomic status: Lower SES families appeared to focus more on alphabetic order than higher SES families. The general letter knowledge expressed in these conversations suggests that everyday interactions are an important component of the home literacy environment and that they differ, in some respects, as a function of child age and family background. PMID:25525295

  12. 77 FR 22540 - Approval and Promulgation of State Implementation Plan Revisions; Infrastructure Requirements for...

    Science.gov (United States)

    2012-04-16

    ... particular, the data and analytical tools available at the time the state develops and submits the SIP for a...) authorizes EPA to correct errors in past actions, such as past approvals of SIP submissions.\\13... errors in past actions on SIP submissions related to PSD programs. See, ``Limitation of Approval...

  13. 78 FR 78796 - Supplemental Applications Proposing Labeling Changes for Approved Drugs and Biological Products...

    Science.gov (United States)

    2013-12-27

    ... Applications Proposing Labeling Changes for Approved Drugs and Biological Products; Correction and Extension of... holders of an approved drug or biological product to change the product labeling to reflect certain types... biological product to change the product labeling to reflect certain types of newly acquired information...

  14. COMMENT ON "PERCHLORATE IDENTIFICATION IN FERTILIZERS" AND THE SUBSEQUENT ADDITION/CORRECTION [LETTER TO EDITOR

    Science.gov (United States)

    Perchlorate contamination has been reported in several fertilizer materials and not just in mined Chile saltpeter, where it is a welo-known natural impurity. To survey fertilizers for perchlorate, two analytical techniques have been applied to 45 products that span agricultural, ...

  15. Corrective Action Plan for Corrective Action Unit 139: Waste Disposal Sites, Nevada Test Site, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2007-07-01

    Corrective Action Unit (CAU) 139, Waste Disposal Sites, is listed in the Federal Facility Agreement and Consent Order (FFACO) of 1996 (FFACO, 1996). CAU 139 consists of seven Corrective Action Sites (CASs) located in Areas 3, 4, 6, and 9 of the Nevada Test Site (NTS), which is located approximately 65 miles (mi) northwest of Las Vegas, Nevada (Figure 1). CAU 139 consists of the following CASs: CAS 03-35-01, Burn Pit; CAS 04-08-02, Waste Disposal Site; CAS 04-99-01, Contaminated Surface Debris; CAS 06-19-02, Waste Disposal Site/Burn Pit; CAS 06-19-03, Waste Disposal Trenches; CAS 09-23-01, Area 9 Gravel Gertie; and CAS 09-34-01, Underground Detection Station. Details of the site history and site characterization results for CAU 139 are provided in the approved Corrective Action Investigation Plan (CAIP) (U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office [NNSA/NSO], 2006) and in the approved Corrective Action Decision Document (CADD) (NNSA/NSO, 2007). The purpose of this Corrective Action Plan (CAP) is to present the detailed scope of work required to implement the recommended corrective actions as specified in Section 4.0 of the approved CADD (NNSA/NSO, 2007). The approved closure activities for CAU 139 include removal of soil and debris contaminated with plutonium (Pu)-239, excavation of geophysical anomalies, removal of surface debris, construction of an engineered soil cover, and implementation of use restrictions (URs). Table 1 presents a summary of CAS-specific closure activities and contaminants of concern (COCs). Specific details of the corrective actions to be performed at each CAS are presented in Section 2.0 of this report.

  16. The Social Name-Letter Effect on Online Social Networks

    OpenAIRE

    Kooti, Farshad; Magno, Gabriel; Weber, Ingmar

    2014-01-01

    The Name-Letter Effect states that people have a preference for brands, places, and even jobs that start with the same letter as their own first name. So Sam might like Snickers and live in Seattle. We use social network data from Twitter and Google+ to replicate this effect in a new environment. We find limited to no support for the Name-Letter Effect on social networks. We do, however, find a very robust Same-Name Effect where, say, Michaels would be more likely to link to other Michaels th...

  17. David Bohm : causality and chance, letters to three women

    CERN Document Server

    2017-01-01

    The letters transcribed in this book were written by physicist David Bohm to three close female acquaintances in the period 1950 to 1956. They provide a background to his causal interpretation of quantum mechanics and the Marxist philosophy that inspired his scientific work in quantum theory, probability and statistical mechanics. In his letters, Bohm reveals the ideas that led to his ground breaking book Causality and Chance in Modern Physics. The political arguments as well as the acute personal problems contained in these letters help to give a rounded, human picture of this leading scientist and twentieth century thinker.

  18. 78 FR 23178 - Federal Housing Administration (FHA) Approval of Lending Institutions and Mortgagees: Streamlined...

    Science.gov (United States)

    2013-04-18

    ... Regulations Division at 202-708- 3055 (this is not a toll-free number). Individuals with speech or hearing... hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay... available at: http://www.hud.gov/offices/adm/hudclips/letters/mortgagee/2009ml.cfm . 2. Technical correction...

  19. 76 FR 4126 - Credit Watch Termination Initiative Termination of Origination Approval Agreements

    Science.gov (United States)

    2011-01-24

    ... new Agreement should be in the form of a letter, accompanied by the CPA's report and corrective action... Newark 11/23/2010........ Philadelphia 209, Woodbridge, NJ 07095. Anchor Mortgage 6260 S Rainbow Las.... Signature One Mortgage Inc..... 5875 S Rainbow Las Vegas 11/15/2010........ Santa Ana Blvd., Ste 110, Las...

  20. Jan of Jenštejn's Personal Hand Corrections in his Epistolary

    Directory of Open Access Journals (Sweden)

    Zdeňka Hledíková

    2014-12-01

    Full Text Available Among autographs by learned men of the late Middle Ages are only a few manuscripts written by an auxiliary copyist but corrected by the author of the text. Such manuscripts served as foundations for end-transcriptions of works destined for the public at large. The collection of 14th-century letters by Archbishop Jan of Jenštejn, published in 1877 as Jenštejn's Epistolary, represent such a transient codex-typus. The article focuses on the adjustment of the quires and character and order of the letters copied, as well as on the text corrections made by another scribe. It concludes that the manuscript originated under the direct supervision of the archbishop, who transmitted the papers of individual letters to the scribe step by step for copying, and then polished their stylistic form and corrected them. The epistolary has never been transcribed into a definitive form for the public.

  1. International Large Detector. Letter of intent

    Energy Technology Data Exchange (ETDEWEB)

    Stoeck, Holger [Sydney Univ., NSW (Australia). Falkiner High Energy Physics Group; Bergauer, Thomas; Dragicevic, Marko [Oesterreichische Akademie der Wissenschaften, Vienna (AT). Inst. fuer Hochenergiephysik] (and others)

    2010-07-01

    In the summer of 2007, the GLD concept study group, whose membership was largely based in Asia, and the LDC concept study group, which was mostly based in Europe with a strong north american membership, joined forces to produce a single Letter of Intent for a detector at the International Linear Collider, and formed the ILD concept group. Both the GLD and LDC concepts used the particle flow algorithm for jet reconstruction and a TPC for the central tracker. The basic parameters of the two concepts such as the size of the detector and the strength of the solenoid field, however, were quite different and had to be unified in order to write this letter of intent for ILD. Also, other critical details such as the interaction region design had to be unified. This was a non-trivial task, neither politically nor sociologically. The newly-formed concept study group, the ILD group, created a management team and engaged in intense studies to define the ILD detector concept by scientifically optimising the detector designs. The process has worked remarkably well, and we present here the outcome of this study as well as the large amount of studies that preceded separately by the two older concept groups. The ILD detector concept is now well defined, even though some technology choices are still open. One of the merits of unifying the detector concepts was that it revitalised the studies on physics performance and detector designs. We believe that the level of sophistication of the simulation and physics analyses has reached a high degree of sophistication for a detector group at this stage. This was achieved through collaboration and competition, and is the result of a productive learning process. The unification had also positive effects on the subdetector R and D efforts. Most R and D on detector technologies relevant to the GLD and LDC groups is being performed within the framework of detector R and D collaborations such as LCTPC, SiLC, CALICE, and FCAL which pursue their

  2. 30 CFR 18.11 - Approval plate.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Approval plate. 18.11 Section 18.11 Mineral... plate. (a)(1) The notice of approval will be accompanied by a photograph of an approval plate, bearing... number shall be added to the original approval number on the approval plate. (Example: Original approval...

  3. Code-switching in letter writing

    Directory of Open Access Journals (Sweden)

    P.S. Sobahle

    2013-02-01

    Full Text Available The study sets out to investigate code switching in letter writing among a small group ofXhosa speaking people. Code switching is found in informal speech and informal writing. It was established from the data that the closer people are, the more code switching there is. Code switching seems to follow a pattern in that it was observed to occur: (a only with certain people (b when talking about certain topics (c when wanting to exclude another person (d when emphasising a point. Code switching also appears to have a 'grammar' of its own. It is not in any way a pidgin. It is clear from the data that code switching does not reflect denial of one's identity. English, being the medium of education for Blacks in South Africa, is therefore bound to be reflected not only in their speech but also in their writing. Die studie het ten doe/ om registeroorskakeling in die skryf van briewe deur 'n klein groepie Xhosasprekendes te ondersoek. Registeroorskakeling word gevind in informele spraak en informele skryfwerk. Daar is uit die data vasgestel dat hoe intiemer mense is hoe meer vind registeroorskakeling plaas. Volgens waarneming blyk dit dat registeroorskakeling 'n patroon volg, want dit het voorgekom: (a net by sekere mense (b wanneer oor sekere onderwerpe gepraat is (c wanneer 'n ander per soon uitgeskakel is (d wanneer 'n mening beklemtoon is. Registeroorskakeling blyk 'n eie grammatika te he. Dit is geensins "pidgin" nie. Dit blyk uit data dat die skrywer se identiteit nie verlore raak tydens registeroorskakeling nie. Omdat Engels die medium van onderrig vir Swartes in Suid-Afrika is, sal dit noodwendig nie net in hulle spraak nie, maar ook in hul skryfwerk gereflekteer word.

  4. Name-letter branding under scrutiny: real products, new algorithms, and the probability of buying.

    Science.gov (United States)

    Stieger, Stefan

    2010-06-01

    People like letters matching their own first and last name initials more than nonname letters. This name-letter effect has also been found for brands, i.e., people like brands resembling their own name letters (initial or first three). This has been termed name-letter branding effect. In the present study of 199 participants, ages 12 to 79 years, this name-letter branding effect was found for a modified design (1) using real products, (2) concentrating on product names rather than brand names, (3) using five different products for each letter of the Roman alphabet, (4) asking for the buying probability, and (5) using recently introduced algorithms, controlling for individual response tendencies (i.e., liking all letters more or less) and general normative popularity of particular letters (i.e., some letters are generally preferred more than other letters).

  5. [1979 letter regarding wading bird locations in Tennessee

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter discusses the known locations of colonial bird nesting species such as herons, egrets, terns, and bank or cliff swallows. Included are the site...

  6. [Letter of Concurrence : Meredosia National Wildlife Refuge Sport Fishing Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter states that the Illinois Department of Conservation concurs with Meredosia NWR's efforts to establish a public use program on the Refuge.

  7. Resource Letter PE-1: Physics and the Environment

    Science.gov (United States)

    Shonle, John I.

    1974-01-01

    Presents a Resource Letter on air pollution, noise pollution, transportation, and solid waste for the purpose of acquainting college physicists with some of the literature and teaching aids. Included are five bibliographies of which four are annotated. (CC)

  8. Toward a statistical mechanics of four letter words

    CERN Document Server

    Stephens, Greg J

    2008-01-01

    We consider words as a network of interacting letters, and approximate the probability distribution of states taken on by this network. Despite the intuition that the rules of English spelling are highly combinatorial (and arbitrary), we find that maximum entropy models consistent with pairwise correlations among letters provide a surprisingly good approximation to the full statistics of four letter words, capturing ~92% of the multi-information among letters and even "discovering" real words that were not represented in the data from which the pairwise correlations were estimated. The maximum entropy model defines an energy landscape on the space of possible words, and local minima in this landscape account for nearly two-thirds of words used in written English.

  9. Army Response Letter & Analysis - signed February 5, 2001

    Science.gov (United States)

    A reply to a letter from Mr. J. Charles Fox, former Administrator for Water requesting to review the proposed decision of the Army Corps of Engineers Sacramento District Department of the Army (DA) permit to Vail Associates.

  10. Sept 2013 NFHL Letter of Map Revision (LOMR)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  11. Love letters to the dead: resurrecting an epistolary art.

    Science.gov (United States)

    Lander, Dorothy A; Graham-Pole, John R

    This article explores the art of letter-writing, specifically to our beloved dead, as a form of autoethnographic research, pedagogy, and care work. As university teachers and qualitative researchers in palliative and end-of-life care, we review the literature and history of epistolary communications with the deceased, as a prelude to writing our own letters. John writes to his long-dead mother and Dorothy to her recently deceased spouse Patrick, each letter followed by a reflective dialogue between us. Through this dialogue, we highlight the potential application of this art, or handcraft, to formal and informal palliative care, and the implications for practice, pedagogy, policy, and research. We propose that such direct, non-mediated, communications can offer a valuable form of healing for bereaved people. The therapeutic potential of letter writing and the abundance of literary and popular culture exemplars of responses from the dead are also largely unexplored in death education and research.

  12. 78 FR 7784 - Health Information Technology Policy Committee Nomination Letters

    Science.gov (United States)

    2013-02-04

    ... From the Federal Register Online via the Government Publishing Office GOVERNMENT ACCOUNTABILITY OFFICE Health Information Technology Policy Committee Nomination Letters AGENCY: Government... Recovery and Reinvestment Act of 2009 (ARRA) established the Health Information Technology Policy...

  13. Consultation letters for medically unexplained physical symptoms in primary care

    NARCIS (Netherlands)

    Hoedeman, Rob; Blankenstein, Annette H.; van der Feltz-Cornelis, Christina M.; Krol, Boudien; Stewart, Roy; Groothoff, Johan W.; van der Feltz-Cornelis, CM

    2010-01-01

    Background In primary care between 10% and 35% of all visits concern patients with medically unexplained physical symptoms (MUPS). MUPS are associated with high medical consumption, significant disabilities and psychiatricmorbidity. Objectives To assess the effectiveness of consultation letters (CLs

  14. 50 CFR 216.259 - Modifications to Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... in the Gulf of Mexico § 216.259 Modifications to Letters of Authorization. (a) Except as provided...

  15. Politeness Strategies in Good-news Business Letters

    Institute of Scientific and Technical Information of China (English)

    毕争; 李纳

    2008-01-01

    This paper analyzes the presentation of politeness in good-news business letters at the lexical,syntactic,and discourse levels based on Leech's Politeness Principle and Brown and Levinson's Face-saving Theory.

  16. Parents’ Talk About Letters With Their Young Children

    Science.gov (United States)

    Treiman, Rebecca; Schmidt, John; Decker, Kristina; Robins, Sarah; Levine, Susan C.; Demir, Özlem Ece

    2015-01-01

    A literacy-related activity that occurs in children's homes—talk about letters in everyday conversations—was examined using data from 50 children who were visited every 4 months between 14 and 50 months. Parents talked about some letters, including those that are common in English words and the first letter of their children's names, especially often. Parents’ focus on the child's initial was especially strong in families of higher socioeconomic status, and the extent to which parents talked about the child's initial during the later sessions of the study was related to the children's kindergarten reading skill. Conversations that included the child's initial were longer than those that did not, and parents presented a variety of information about this letter. PMID:26014495

  17. Letter from Federal Power Commission [Havasu National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Federal Power Commission to the Secretary of the Interior. It confirms that the Federal Power Commission has no plans that...

  18. Congruence between parents' and children's three-letter Holland codes.

    Science.gov (United States)

    Miller, M J

    1994-06-01

    In this study the associations of three-letter Holland codes of 40 parents and their children (20 mothers and daughters, 20 fathers and sons) were analyzed. Implications for school counselors, based on the results, are briefly discussed.

  19. Ataluren: first global approval.

    Science.gov (United States)

    Ryan, Nicola J

    2014-09-01

    Nonsense mutations are implicated in 5-70 % of individual cases of most inherited diseases, including Duchenne muscular dystrophy (DMD) and cystic fibrosis. Ataluren (Translarna™) is an orally available, small molecule compound that targets nonsense mutations, and is the first drug in its class. Ataluren appears to allow cellular machinery to read through premature stop codons in mRNA, enabling the translation process to produce full-length, functional proteins. This article summarizes the milestones in the development of ataluren leading to its conditional first approval for nonsense mutation DMD.

  20. Letter-By-Letter Reading: Natural Recovery and Response to Treatment

    Science.gov (United States)

    Beeson, Pélagie M.; Magloire, Joël G.; Robey, Randall R.

    2005-01-01

    The present investigation provides a longitudinal study of an individual (RB) with acquired alexia following left posterior cerebral artery stroke. At initial testing, RB exhibited acquired alexia characterized by letter-by-letter (LBL) reading, mild anomic aphasia, and acquired agraphia. Repeated measures of reading accuracy and rate were collected for single words and text over the course of one year, along with probes of naming and spelling abilities. Improvements associated with natural recovery (i.e., without treatment) were documented up to the fourth month post onset, when text reading appeared to be relatively stable. Multiple oral reading (MOR) treatment was initiated at 22 weeks post-stroke, and additional improvements in reading rate and accuracy for text were documented that were greater than those expected on the basis of spontaneous recovery alone. Over the course of one year, reading reaction times for single words improved, and the word-length effect that is the hallmark of LBL reading diminished. RB's response to treatment supports the therapeutic value of MOR treatment to in LBL readers. His residual impairment of reading and spelling one-year post stroke raised the question as to whether further progress was impeded by degraded orthographic knowledge. PMID:16518009

  1. Color associations for days and letters across different languages

    Directory of Open Access Journals (Sweden)

    Romke eRouw

    2014-05-01

    Full Text Available While colors are commonplace in everyday metaphors, relatively little is known about implicit color associations to linguistic or semantic concepts in a general population. In this study, we test color associations for ordered linguistic concepts (letters and days. The culture and language specificity of these effects was examined in a large group (457 of Dutch-speaking participants, 92 English-speaking participants, and 49 Hindi-speaking participants. Non-random distributions of color choices were revealed; consistencies were found across the three language groups in color preferences for both days and letters. Interestingly, while the Hindi-speaking participants were presented with letter stimuli matched on phonology, their pattern of letter-to-color preferences still showed similarities with Dutch- and English-speaking participants. Furthermore, we found that that the color preferences corresponded between participants indicating to have conscious color experiences with letters or days (putative synesthetes and participants who do not (non-synesthetes. We also explored possible mechanisms underlying the color preferences. There were a few specific associations, including red for A, red for Monday, and white for Sunday. We also explored more general mechanisms, such as overall color preferences shown by Simner et al (2005. While certainly not all variation can be explained or predicted, the results show that regularities are present in color-to-letter or color-to-day preferences in both putative synesthetes and non-synesthetes across languages. Both letter-to-color and day-to-color preferences were influenced by multiple factors. The findings support a notion of abstract concepts (such as days and letters that are not represented in isolation, but are connected to perceptual representational systems. Interestingly, at least some of these connections to color representations are shared across different language/cultural groups.

  2. On a Field, Sable, the Letter A, Gules——Comments on The Scarlet Letter%On a Field, Sable, the Letter A, Gules--Comments on The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王瑾

    2007-01-01

    Nathaniel Hawthorne's The Scarlet Letter is a moral and psychological novel which focuses on human nature and the effects of sin. This paper is divided into two parts. The first part focuses on the analysis ofa sable field and the second part is about gules letter A. Actually the two parts are the answers to where the sin is and how to achieve redemption. Hawthorne's thoughts,good wishes and artistic characters are fully expressed in it.

  3. Politeness Strategies in English and Chinese Business Letters

    Institute of Scientific and Technical Information of China (English)

    查琳琳

    2014-01-01

    This paper explores similarities and differences in the application of positive and negative politeness strategies to Eng-lish and Chinese business letters and illuminates underlying causes of such similarities and differences. The results indicate that English and Chinese business letters have some common features and great discrepancies in categories and the distribution of posi-tive and negative politeness strategies. It is argued that common situational factors, different cultural backgrounds and different syntactic features result in their similarities and differences.

  4. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment of jaws and ... Implant Surgery Dental Implant Surgery Dental implant surgery is, of course, surgery, and is best performed by ...

  5. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... and Craniofacial Surgery Cleft Lip/Palate and Craniofacial Surgery A cleft lip may require one or more ... find out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment ...

  6. Corrective Jaw Surgery

    Science.gov (United States)

    ... and Craniofacial Surgery Cleft Lip/Palate and Craniofacial Surgery A cleft lip may require one or more ... find out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment ...

  7. The effects of alphabet and expertise on letter perception.

    Science.gov (United States)

    Wiley, Robert W; Wilson, Colin; Rapp, Brenda

    2016-08-01

    Long-standing questions in human perception concern the nature of the visual features that underlie letter recognition and the extent to which the visual processing of letters is affected by differences in alphabets and levels of viewer expertise. We examined these issues in a novel approach using a same-different judgment task on pairs of letters from the Arabic alphabet with 2 participant groups: 1 with no prior exposure to Arabic and 1 with reading proficiency. Hierarchical clustering and linear mixed-effects modeling of reaction times and accuracy provide evidence that both the specific characteristics of the alphabet and observers' previous experience with it affect how letters are perceived and visually processed. The findings of this research further our understanding of the multiple factors that affect letter perception and support the view of a visual system that dynamically adjusts its weighting of visual features as expert readers come to more efficiently and effectively discriminate the letters of the specific alphabet they are viewing. (PsycINFO Database Record

  8. Obinutuzumab: first global approval.

    Science.gov (United States)

    Cameron, Fiona; McCormack, Paul L

    2014-01-01

    Obinutuzumab (Gazyva™) is an intravenously administered, humanized and glycoengineered, type II anti-CD20 monoclonal antibody for the treatment of B-cell malignancies. It is approved in the US for use in combination with chlorambucil for the first-line treatment of chronic lymphocytic leukaemia (CLL), and has been filed for approval in the EU in this indication. The antibody is based on GlycArt Biotechnology's (later Roche Glycart AG) proprietary GlycoMAb® technology, which uses glycoengineered antibodies that specifically increase antibody-dependent cellular cytotoxicity and thereby increase immune-mediated target cell death. Obinutuzumab is a type II anti-CD20 antibody that induces enhanced direct cell death. The monoclonal antibody is in worldwide phase III development with Roche and its subsidiaries, Genentech and Chugai Pharmaceutical, as well as Biogen Idec, for diffuse large B-cell lymphoma and non-Hodgkin's lymphoma generally, and is also in phase III development in countries outside of the US and EU for CLL.

  9. Safinamide: first global approval.

    Science.gov (United States)

    Deeks, Emma D

    2015-04-01

    Safinamide (Xadago(®)) is an oral α-aminoamide derivative developed by Newron for the treatment of Parkinson's disease (PD). The drug has both dopaminergic properties (highly selective and reversible inhibition of monoamine oxidase-B) and non-dopaminergic properties (selective sodium channel blockade and calcium channel modulation, with consequent inhibition of excessive glutamate release). Safinamide is approved in the EU, Iceland, Lichtenstein and Norway, as an add-on therapy to stable-dose levodopa, alone or in combination with other PD therapies in mid- to late-stage fluctuating PD patients; regulatory submissions have also been filed in the USA and Switzerland for its use in this indication. Additional submissions have been made in the USA, Iceland, Lichtenstein, Norway and Switzerland for early-stage PD. Safinamide has also undergone phase II investigation in PD patients with drug-induced dyskinesia (France, Germany, Austria, Canada and South Africa) or cognitive impairment (USA and Spain). This article summarizes the milestones in the development of safinamide leading to its first approval for PD.

  10. Letters to those who Dare Feel: Using Reflective Letter-Writing to Explore the Emotionality of Research

    Directory of Open Access Journals (Sweden)

    Kathleen Pithouse-Morgan

    2012-02-01

    Full Text Available Using reflective letter-writing as a method of generating data, a group of four researchers embarked on a collaborative autoethnographic inquiry into the emotional dimensions of researching social aspects of HIV & AIDS. In this article, we use the medium of a narrative dialogue to represent and re-examine our reflective letter-writing method. The dialogue draws attention to key features of reflective letter-writing as a collaborative autoethnographic research method and, in so doing, highlights and explores the nature, potential significance, and challenges of this method. Our discussion points to the value of a collaborative process of reflective letter-writing as a way for researchers to access and portray emotional aspects of their research experience, to deepen their engagement with these emotional dimensions, and to gain insight into their own and others' lived research experiences.

  11. A linguistic kaleidoscope of the Malay letter; The case of the eighteenth century official letters from the Sultanate of Buton

    Directory of Open Access Journals (Sweden)

    S. Suryadi

    2015-07-01

    Full Text Available The Malay letters make up the largest category of documents among the Malay manuscripts preserved at Leiden University Library, the Netherlands. The corpus represents the scope of the territories under Dutch East Indies authority during the colonial era. In fact, they are authentic documents which denote not only political contact between the local kingdoms in the Archipelago (Nusantara with the Dutch East Indies government in Batavia during colonial times but also constitute an important source for the study of the historical development of the Malay language. This essay looks at the language characters of such letters which came from the court of Buton in Southeast Sulawesi. It aims to sketch the linguistic variety of the classical Malay language represented in its eighteenth century letter-writing tradition. Having specific diction and features that confirm local influences, the language of the letters shows distinctiveness in terms of phonology, morphology and syntax.

  12. Letter - Reply: Meteors in Australian Aboriginal Dreamings

    Science.gov (United States)

    Hamacher, Duane W.

    2011-06-01

    In response to the letter by Gorelli (2010) about Hamacher & Norris (2010), he is quite right about Aboriginal people witnessing impact events in Australia. There are several oral traditions regarding impact sites, some of which were probably witnessed, as Gorelli pointed out. The Henbury craters he mentions, with a young age of only ∼ 4200 years, have oral traditions that seem to describe a cosmic impact, including an aversion to drinking water that collects in the craters in fear that the fire-devil (which came from the sun, according to an Elder) would rain iron in them again. Other impact sites, such as Gosse's Bluff crater (Tnorala in the Arrernte language) and Wolfe Creek crater (Kandimalal in the Djaru language) have associated impact stories, despite their old ages (142 Ma and ∼0.3 Ma, respectively). In addition, many fireball and airburst events are described in Aboriginal oral traditions, a number of which seem to indicate impact events that are unknown to Western science. I have published a full treatise of meteorite falls and impact events in Australian Aboriginal culture that I would like to bring to the attention of Gorelli and WGN readers (Hamacher & Norris, 2009). Although our paper was published in the 2009 volume of Archaeoastronomy, it did not appear in print until just recently, which is probably why it has gone unnoticed. Recent papers describing the association between meteorites and Aboriginal cosmology (Hamacher, 2011) and comets in Aboriginal culture (Hamacher & Norris, 2011) have also been published, and would likely be of interest to WGN readers. I heartily agree with Gorelli that oral traditions are fast disappearing, taking with them a wealth of information about not only that peoples' culture, but also about past geologic and astronomical events, such as meteorite falls and cosmic impacts (a branch of the growing field of Geomythology). There is an old saying that "when a man dies, a library goes with him". This is certainly the

  13. Drugs Approved for Cervical Cancer

    Science.gov (United States)

    ... Human Papillomavirus (HPV) Nonavalent Vaccine Recombinant Human Papillomavirus (HPV) Quadrivalent Vaccine Drugs Approved to Treat Cervical Cancer Avastin (Bevacizumab) Bevacizumab Blenoxane (Bleomycin) Bleomycin Hycamtin (Topotecan ...

  14. New color correction method for multi-view video using disparity vector information

    Institute of Scientific and Technical Information of China (English)

    Randi Fu; Feng Shao; Gangyi Jiang; Mei Yu

    2008-01-01

    Color inconsistency is an urgent problem to be solved in free viewpoint television. In this letter, a new color correction method is proposed by using disparity vector information. At first, we separate foreground and background from the scene with a method of mean-removed disparity estimation. Then the correction parameters are estimated by adopting linear fitting for foreground and background regions, respectively. Next, with expectation-maximization algorithm, we integrate correction parameters of foreground and background to get the final corrected image. Finally, video tracking technique is performed to correct multi-view video. Experimental results show that the proposed method is quite effective.

  15. Using Incremental Rehearsal to Teach Letter Sounds to English Language Learners

    Science.gov (United States)

    Rahn, Naomi L.; Wilson, Jennifer; Egan, Andrea; Brandes, Dana; Kunkel, Amy; Peterson, Meredith; McComas, Jennifer

    2015-01-01

    This study examined the effects of incremental rehearsal (IR) on letter sound expression for one kindergarten and one first grade English learner who were below district benchmark for letter sound fluency. A single-subject multiple-baseline design across sets of unknown letter sounds was used to evaluate the effect of IR on letter-sound expression…

  16. Linking the Shapes of Alphabet Letters to Their Sounds: The Case of Hebrew

    Science.gov (United States)

    Treiman, Rebecca; Levin, Iris; Kessler, Brett

    2012-01-01

    Learning the sounds of letters is an important part of learning a writing system. Most previous studies of this process have examined English, focusing on variations in the phonetic iconicity of letter names as a reason why some letter sounds (such as that of b, where the sound is at the beginning of the letter's name) are easier to learn than…

  17. Preventive letter: doubling the return rate after gestational diabetes mellitus.

    Science.gov (United States)

    Olmos, Pablo R; Borzone, Gisella R; Berkowitz, Loni; Mertens, Nicolás; Busso, Dolores; Santos, José L; Poblete, José A; Vera, Claudio; Belmar, Cristián; Goldenberg, Denisse; Samith, Bárbara; Acosta, Ana M; Escalona, Manuel

    2015-05-01

    To measure the impact of a "Preventive Letter" designed to encourage the return of gestational diabetes mellitus (GDM) mothers to follow up visit after delivery, in the context of a worldwide concern about low return rates after delivery of these patients. Mothers with GDM require medical evaluation and an oral glucose tolerance test (OGTT) 6 weeks after delivery, in order to: [a] confirm remission of GDM and [b] provide advice on the prevention of type 2 diabetes. In the year 2003 we developed a "Preventive Letter", containing three aspects: [a] current treatment, [b] suggested management during labor, and [c] a stapled laboratory order for OGTT to be performed 6 weeks after delivery. The return rate after delivery was assessed in two groups of GDM mothers: [a] "Without Preventive Letter" (n = 253), and "With Preventive Letter" (n = 215). Both groups, similar with respect to age (33.0 ± 5.4 and 32.3 ± 4.9 years respectively, p = 0.166) and education time (14.9 ± 1.8 and 15.0 ± 1.8 years respectively, p = 0.494), showed a significant difference in the 1-year return rate after delivery, as assessed by the Kaplan-Meier test: 32.0 % for the group "Without Preventive Letter", and 76.0 % for the group "With Preventive Letter" (p return rate after delivery of GDM mothers was 2.4 times higher in the group "With Preventive Letter" than in the group without it. We believe that this low-cost approach could be useful in other institutions caring for pregnant women with diabetes.

  18. Pseudo-synesthesia through reading books with colored letters.

    Science.gov (United States)

    Colizoli, Olympia; Murre, Jaap M J; Rouw, Romke

    2012-01-01

    Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter 'a' always appears as light blue). In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words) was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14) = 5.85, p = .030). Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13) = 0.51, p = .05). The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14) = 2.79, p = .014) and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term 'synesthetic' training program.

  19. Pseudo-synesthesia through reading books with colored letters.

    Directory of Open Access Journals (Sweden)

    Olympia Colizoli

    Full Text Available BACKGROUND: Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter 'a' always appears as light blue. In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. METHODOLOGY/PRINCIPAL FINDINGS: Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14 = 5.85, p = .030. Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13 = 0.51, p = .05. The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14 = 2.79, p = .014 and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. CONCLUSION/SIGNIFICANCE: To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term 'synesthetic' training program.

  20. Phonological awareness and the use of phonological similarity in letter-sound learning.

    Science.gov (United States)

    de Jong, Peter F

    2007-11-01

    The effects of the phonological similarity between a letter sound and the sound in a spoken word, and phonological awareness on letter-sound learning were examined. Two groups of 41 kindergartners were taught four letter sounds. First, both groups had to learn the associations between four symbols and four familiar words. Next, both groups were taught the letter sounds that were paired to these same symbols. Each letter sound corresponded to the first sound of the word that was previously associated with that symbol in the phonological similarity group, whereas such a relation was absent in the other group. In addition, measures of vocabulary, letter knowledge, and phonological awareness were administered. Phonological similarity facilitated letter-sound learning. Individual differences in phonological awareness had a strong effect on letter-sound learning even after current letter knowledge was controlled. Unexpectedly, the effects of phonological awareness and the ability to use phonological similarity on letter-sound learning were found to be independent.

  1. 77 FR 22533 - Approval and Promulgation of Implementation Plans; Tennessee; 110(a)(1) and (2) Infrastructure...

    Science.gov (United States)

    2012-04-16

    ... and analytical tools available at the time the state develops and submits the SIP for a new or revised... correct errors in past actions, such as past approvals of SIP submissions.\\17\\ Significantly, EPA's...,'' 76 FR 21639 (April 18, 2011). \\17\\ EPA has recently utilized this authority to correct errors in...

  2. 76 FR 41088 - Approval and Promulgation of Implementation Plans; Kentucky; 110(a)(1) and (2) Infrastructure...

    Science.gov (United States)

    2011-07-13

    ... vary depending upon the facts and circumstances. In particular, the data and analytical tools available...\\ Section 110(k)(6) authorizes EPA to correct errors in past actions, such as past approvals of SIP... recently utilized this authority to correct errors in past actions on SIP submissions related to...

  3. 76 FR 40248 - Approval and Promulgation of Implementation Plans; Connecticut, Maine, New Hampshire and Rhode...

    Science.gov (United States)

    2011-07-08

    ... particular, the data and analytical tools available at the time the state develops and submits the SIP for a... CAA.\\13\\ Section 110(k)(6) authorizes EPA to correct errors in past actions, such as past approvals of... has recently utilized this authority to correct errors in past actions on SIP submissions related...

  4. 76 FR 41123 - Approval and Promulgation of Implementation Plans; Mississippi; 110(a)(1) and (2) Infrastructure...

    Science.gov (United States)

    2011-07-13

    ... and analytical tools available at the time the state develops and submits the SIP for a new or revised... CAA.\\15\\ Section 110(k)(6) authorizes EPA to correct errors in past actions, such as past approvals of... has recently utilized this authority to correct errors in past actions on SIP submissions related...

  5. 76 FR 41111 - Approval and Promulgation of Implementation Plans; South Carolina; 110(a)(1) and (2...

    Science.gov (United States)

    2011-07-13

    ... correcting an inadvertent error and responding to adverse comments received on EPA's March 17, 2011, proposed... vary depending upon the facts and circumstances. In particular, the data and analytical tools available...) authorizes EPA to correct errors in past actions, such as past approvals of SIP...

  6. 76 FR 41100 - Approval and Promulgation of Implementation Plans; Alabama; 110(a)(1) and (2) Infrastructure...

    Science.gov (United States)

    2011-07-13

    ... depending upon the facts and circumstances. In particular, the data and analytical tools available at the...) authorizes EPA to correct errors in past actions, such as past approvals of SIP submissions.\\16... this authority to correct errors in past actions on SIP submissions related to PSD programs....

  7. FDA-Approved HIV Medicines

    Science.gov (United States)

    HIV Treatment FDA-Approved HIV Medicines (Last updated 2/27/2017; last reviewed 2/27/2017) Treatment with HIV medicines is ... approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in the ...

  8. Extra-large letter spacing improves reading in dyslexia.

    Science.gov (United States)

    Zorzi, Marco; Barbiero, Chiara; Facoetti, Andrea; Lonciari, Isabella; Carrozzi, Marco; Montico, Marcella; Bravar, Laura; George, Florence; Pech-Georgel, Catherine; Ziegler, Johannes C

    2012-07-10

    Although the causes of dyslexia are still debated, all researchers agree that the main challenge is to find ways that allow a child with dyslexia to read more words in less time, because reading more is undisputedly the most efficient intervention for dyslexia. Sophisticated training programs exist, but they typically target the component skills of reading, such as phonological awareness. After the component skills have improved, the main challenge remains (that is, reading deficits must be treated by reading more--a vicious circle for a dyslexic child). Here, we show that a simple manipulation of letter spacing substantially improved text reading performance on the fly (without any training) in a large, unselected sample of Italian and French dyslexic children. Extra-large letter spacing helps reading, because dyslexics are abnormally affected by crowding, a perceptual phenomenon with detrimental effects on letter recognition that is modulated by the spacing between letters. Extra-large letter spacing may help to break the vicious circle by rendering the reading material more easily accessible.

  9. Melanie Klein's letters addressed to Marcelle Spira (1955-1960).

    Science.gov (United States)

    Quinodoz, Jean-Michel

    2009-12-01

    Between 1955 and 1960, Melanie Klein wrote some 45 hitherto unpublished letters to Marcelle Spira, the Swiss psychoanalyst living at that time in Geneva. In 2006, after Spira's death, these letters were deposited with the Raymond de Saussure Psychoanalysis Centre in Geneva. They are the only known letters that Klein addressed to her psychoanalyst colleagues. Several topics are mentioned in them: (1) the meetings between the two women in Geneva and London; (2) Spira's contribution to Boulanger's translation into French of The Psychoanalysis of Children, which Klein herself carefully revised; (3) the papers that Klein was at that time working on, including Envy and Gratitude; (4) Spira's own work; (5) the difficulties that Spira, a Kleinian psychoanalyst who trained in Buenos Aires, was encountering in her attempt to be admitted to the Swiss Psychoanalytical Society; and (6) a few items of personal and family news. In addition to the invaluable historical information that these letters provide, they offer us a very moving epistolary self-portrait of Melanie Klein, enabling us to discover her personality in the final years of her life - she died in September 1960, just two months after writing her last letter to Spira.

  10. Are All Letters Really Processed Equally and in Parallel? Further Evidence of a Robust First Letter Advantage

    Science.gov (United States)

    Scaltritti, Michele; Balota, David A.

    2013-01-01

    This present study examined accuracy and response latency of letter processing as a function of position within a horizontal array. In a series of 4 Experiments, target-strings were briefly (33 ms for Experiment 1 to 3, 83 ms for Experiment 4) displayed and both forward and backward masked. Participants then made a two alternative forced choice. The two alternative responses differed just in one element of the string, and position of mismatch was systematically manipulated. In Experiment 1, words of different lengths (from 3 to 6 letters) were presented in separate blocks. Across different lengths, there was a robust advantage in performance when the alternative response was different for the letter occurring at the first position, compared to when the difference occurred at any other position. Experiment 2 replicated this finding with the same materials used in Experiment 1, but with words of different lengths randomly intermixed within blocks. Experiment 3 provided evidence of the first position advantage with legal nonwords and strings of consonants, but did not provide any first position advantage for non-alphabetic symbols. The lack of a first position advantage for symbols was replicated in Experiment 4, where target-strings were displayed for a longer duration (83 ms). Taken together these results suggest that the first position advantage is a phenomenon that occurs specifically and selectively for letters, independent of lexical constraints. We argue that the results are consistent with models that assume a processing advantage for coding letters in the first position, and are inconsistent with the commonly held assumption in visual word recognition models that letters are equally processed in parallel independent of letter position. PMID:24012723

  11. Electronic Approval of Invoices (AEF)

    CERN Multimedia

    2004-01-01

    With a view to the simplification of administrative procedures, AS and FI Departments have completed the second phase of the new procedure for the electronic approval of invoices via the EDH application. The aim of this new procedure is to rationalise the invoice approval process, notably by eliminating paper copies from the approval circuit. This will simplify the processing of invoices and facilitate their timely settlement, while at the same time maintaining a high level of security. Phase II includes handling the electronic approval process of invoices whose amounts do not correspond exactly to those of the associated orders. In such cases, budgetary approval is required for the entire invoiced amount. Further information can be obtained at : http://ais.cern.ch/projs/AEF/help/F_help.htm Phase II of the procedure will be introduced gradually with effect from April 2004. Finance Department, Accounts Payable Section Tel: 72295 Organisation and Procedures Tel: 75885 Information Technologies Department,...

  12. Crowding and visual acuity measured in adults using paediatric test letters, pictures and symbols.

    Science.gov (United States)

    Lalor, Sarah J H; Formankiewicz, Monika A; Waugh, Sarah J

    2016-04-01

    Crowding refers to the degradation of visual acuity for target optotypes with, versus without, surrounding features. Crowding is important clinically, however the effect of target-flanker spacing on acuity for symbols and pictures, compared to letters, has not been investigated. Five adults with corrected-to-normal vision had visual acuity measured for modified single target versions of Kay Pictures, Lea Symbols, HOTV and Cambridge Crowding Cards, tests. Single optotypes were presented in isolation and with surrounding features placed 0-5 stroke-widths away. Visual acuity measured with Kay Picture optotypes is 0.13-0.19logMAR better than for other test optotypes and varies significantly across picture. The magnitude of crowding is strongest when the surrounding features abut, or are placed 1 stroke-width away from the target optotype. The slope of the psychometric function is steeper in the region just beyond maximum crowding. Crowding is strongest and the psychometric function steepest, with the Cambridge Crowding Cards arrangement, than when any single optotype is surrounded by a box. Estimates of crowding extent are less variable across test when expressed in units of stroke-width, than optotype-width. Crowding for single target presentations of letters, symbols and pictures used in paediatric visual acuity tests can be maximised and made more sensitive to change in visual acuity, by careful selection of optotype, by surrounding the target with similar flankers, and by using a closer target-flanker separation than half an optotype-width.

  13. Are all Semitic languages immune to letter transpositions? The case of Maltese.

    Science.gov (United States)

    Perea, Manuel; Gatt, Albert; Moret-Tatay, Carmen; Fabri, Ray

    2012-10-01

    Recent research using the rapid serial visual presentation (RSVP) paradigm with English sentences that included words with letter transpositions (e.g., jugde) has shown that participants can readily reproduce the correctly spelled sentences with little cost; in contrast, there is a dramatic reading cost with root-derived Hebrew words (Velan & Frost, Psychonomic Bulletin & Review 14:913-918, 2007, Cognition 118:141-156, 2011). This divergence could be due to (1) the processing of root-derived words in Semitic languages or (2) the peculiarities of the transitional probabilities in root-derived Hebrew words. Unlike Hebrew, Maltese is a Semitic language that does not omit vowel information in print and whose morphology also has a significant non-Semitic (mostly Romance) morphology. Here, we employed the same RSVP technique used by Velan and Frost (Psychonomic Bulletin & Review 14:913-918, 2007, Cognition 118:141-156, 2011), this time with Maltese (and English) sentences. The results showed that Maltese-English bilinguals were able to reproduce the Maltese words-regardless of whether they were misspelled (involving the transposition of two letters from the consonantal root) or not, with no reading cost-just as in English. The apparent divergences between the RSVP data with Hebrew versus Maltese sentences are likely due to the combination of the characteristics of the Hebrew orthographic system with the Semitic morphology.

  14. Detection and identification of crowded mirror-image letters in normal peripheral vision.

    Science.gov (United States)

    Chung, Susana T L

    2010-02-01

    Performance for discriminating single mirror-image letters in peripheral vision can be as good as that in central vision, provided that letter size is scaled appropriately [Higgins, K. E., Arditi, A., & Knoblauch, K. (1996). Detection and identification of mirror-image letter pairs in central and peripheral vision. Vision Research, 36, 331-337]. In this study, we asked whether or not there is a reduction in performance for discriminating mirror-image letters when the letters are flanked closely by other letters, compared with unflanked (single) letters; and if so, whether or not this effect is greater in peripheral than in central vision. We compared contrast thresholds for detecting and identifying mirror-image letters "b" and "d" for a range of letter separations, at the fovea and 10 degrees eccentricity, for letters that were scaled in size. For comparison, thresholds were also determined for a pair of non-mirror-image letters "o" and "x". Our principal finding is that there is an additional loss in sensitivity for identifying mirror-image letters ("bd"), compared with non-mirror-image letters ("ox"), when the letters are flanked closely by other letters. The effect is greater in peripheral than central vision. An auxiliary experiment comparing thresholds for letters "d" and "q" vs. "b" and "d" shows that the additional loss in sensitivity for identifying crowded mirror-image letters cannot be attributed to the similarity in letter features between the two letters, but instead, is specific to the axis of symmetry. Our results suggest that in the presence of proximal objects, there is a specific loss in sensitivity for processing broad-band left-right mirror images in peripheral vision.

  15. A Novel Handwritten Letter Recognizer Using Enhanced Evolutionary Neural Network

    Science.gov (United States)

    Mahmoudi, Fariborz; Mirzashaeri, Mohsen; Shahamatnia, Ehsan; Faridnia, Saed

    This paper introduces a novel design for handwritten letter recognition by employing a hybrid back-propagation neural network with an enhanced evolutionary algorithm. Feeding the neural network consists of a new approach which is invariant to translation, rotation, and scaling of input letters. Evolutionary algorithm is used for the global search of the search space and the back-propagation algorithm is used for the local search. The results have been computed by implementing this approach for recognizing 26 English capital letters in the handwritings of different people. The computational results show that the neural network reaches very satisfying results with relatively scarce input data and a promising performance improvement in convergence of the hybrid evolutionary back-propagation algorithms is exhibited.

  16. Romanian letter-writing: a cultural-rhetorical perspective (II

    Directory of Open Access Journals (Sweden)

    Gabriela-Iuliana Morcov

    2016-08-01

    Full Text Available The article aims at revealing the features of Romanian letter-writing during its stages of formation and consolidation. The structural and the stylistic analysis of letters is carried out with regard to the composition of the documents written in Old Romanian according to the requirements imposed by the Slavonic template and with regard to the rhetorical division of the three styles: the simple style, the middle style and the grand style. The description of the Old Romanian epistolary style is based on a taxonomy inspired by Roman Jakobson’s functional communicative model (1964. Following the six factors identified by Jakobson, letters are classified according to the socio-cultural status and the communicative competence of the addresser and of the addressee and in line with the context, the channel and the linguistic code used to write them.

  17. Letters from ainsworth: contesting the 'organization' of attachment.

    Science.gov (United States)

    Landa, Sophie; Duschinsky, Robbie

    2013-05-01

    As Main (1999) noted in her obituary for Mary Ainsworth, 'she was interacting weekly by letter and manuscript with her mentor and friend, John Bowlby, and their academic correspondence formed an important part of her, and implicitly our, life.' These letters of Ainsworth to John Bowlby during the 1980s, available in the Wellcome Trust Library in London, contain valuable reflections on the work of her pupils to extend her system of classifying infant behaviour in the Strange Situation Procedure. Mary Main proposed a D classification and interpreted such behaviour as a breakdown in an ABC strategy caused by a conflict between a disposition to approach and flee from the caregiver. Patricia Crittenden extended the subtypes of A and C, using a developmental model of information processing, and observed that they could be used together in A/C combinations. These letters offer insight into Ainsworth's intellectual rationale for encouraging both Main and Crittenden in their conflicting endeavours.

  18. Spatial representations of numbers and letters in children

    Directory of Open Access Journals (Sweden)

    Jan eLonnemann

    2013-08-01

    Full Text Available Different lines of evidence suggest that children’s mental representations of numbers are spatially organized in form of a mental number line. It is, however, still unclear whether a spatial organization is specific for the numerical domain or also applies to other ordinal sequences in children. In the present study, children (n = 129 aged 8-9 years were asked to indicate the midpoint of lines flanked by task-irrelevant digits or letters. We found that the localization of the midpoint was systematically biased towards the larger digit. A similar, but less pronounced, effect was detected for letters with spatial biases towards the letter succeeding in the alphabet. Instead of assuming domain-specific forms of spatial representations, we suggest that ordinal information expressing relations between different items of a sequence might be spatially coded in children, whereby numbers seem to convey this kind of information in the most salient way.

  19. The Archetypes of the Characters in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    成程

    2015-01-01

    Nathaniel Hawthorne and his works are deeply influenced by the religion and the Holy Bible.It has many corresponding relationships between the Biblical allusions and the characters,plot and theme in the Scarlet Letter.Hawthorne gave the novel symbolic characters in order to give this symbolism novel a deeper connotation,by borrowing quite a lot of the Biblical allusions.The Scarlet Letter established Hawthorne as the most important 19th century romantic novelist in the United States.This paper attempts to analyze the characteristics and the life experience of the figures in the novel,such as Hester Prynne,Chillingworth,Dimmesdale and Pearl by using the archetypal criticism.The paper also will compare the novel to the Holy Bible so that we canfind the archetypes of the Holy Bible hidden in the Scarlet Letter.

  20. The Archetypes of the Characters in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    成程

    2015-01-01

    Nathaniel Hawthorne and his works are deeply influenced by the religion and the Holy Bible.It has many corresponding relationships between the Biblical allusions and the characters,plot and theme in the Scarlet Letter.Hawthorne gave the novel symbolic characters in order to give this symbolism novel a deeper connotation,by borrowing quite a lot of the Biblical allusions.The Scarlet Letter established Hawthorne as the most important 19 th century romantic novelist in the United States.This paper attempts to analyze the characteristics and the life experience of the figures in the novel,such as Hester Prynne,Chillingworth,Dimmesdale and Pearl by using the archetypal criticism.The paper also will compare the novel to the Holy Bible so that we can find the archetypes of the Holy Bible hidden in the Scarlet Letter.

  1. Musical expertise affects neural bases of letter recognition.

    Science.gov (United States)

    Proverbio, Alice Mado; Manfredi, Mirella; Zani, Alberto; Adorni, Roberta

    2013-02-01

    It is known that early music learning (playing of an instrument) modifies functional brain structure (both white and gray matter) and connectivity, especially callosal transfer, motor control/coordination and auditory processing. We compared visual processing of notes and words in 15 professional musicians and 15 controls by recording their synchronized bioelectrical activity (ERPs) in response to words and notes. We found that musical training in childhood (from age ~8 years) modifies neural mechanisms of word reading, whatever the genetic predisposition, which was unknown. While letter processing was strongly left-lateralized in controls, the fusiform (BA37) and inferior occipital gyri (BA18) were activated in both hemispheres in musicians for both word and music processing. The evidence that the neural mechanism of letter processing differed in musicians and controls (being absolutely bilateral in musicians) suggests that musical expertise modifies the neural mechanisms of letter reading.

  2. A common left occipito-temporal dysfunction in developmental dyslexia and acquired letter-by-letter reading?

    Directory of Open Access Journals (Sweden)

    Fabio Richlan

    Full Text Available We used fMRI to examine functional brain abnormalities of German-speaking dyslexics who suffer from slow effortful reading but not from a reading accuracy problem. Similar to acquired cases of letter-by-letter reading, the developmental cases exhibited an abnormal strong effect of length (i.e., number of letters on response time for words and pseudowords.Corresponding to lesions of left occipito-temporal (OT regions in acquired cases, we found a dysfunction of this region in our developmental cases who failed to exhibit responsiveness of left OT regions to the length of words and pseudowords. This abnormality in the left OT cortex was accompanied by absent responsiveness to increased sublexical reading demands in phonological inferior frontal gyrus (IFG regions. Interestingly, there was no abnormality in the left superior temporal cortex which--corresponding to the onological deficit explanation--is considered to be the prime locus of the reading difficulties of developmental dyslexia cases.The present functional imaging results suggest that developmental dyslexia similar to acquired letter-by-letter reading is due to a primary dysfunction of left OT regions.

  3. Standardized Letter of Recommendation for Otolaryngology Residency Selection

    Science.gov (United States)

    Perkins, Jonathan N.; Liang, Conan; McFann, Kim; Abaza, Mona M.; Streubel, Sven-Olrik; Prager, Jeremy D.

    2013-01-01

    Objectives/Hypothesis Develop a standardized letter of recommendation (SLOR) for otolaryngology residency application that investigates the qualities desired in residents and letter writer’s experience. Compare this SLOR to narrative letters of recommendation (NLOR). Study Design Prospective SLOR/NLOR Comparison. Methods The SLOR was sent to a NLOR writer for each applicant. The applicant’s NLOR/SLOR pair was blinded and ranked in seven categories by three reviewers. Inter-rater reliability and NLOR/SLOR rankings were compared. Means of cumulative NLOR and SLOR scores were compared to our departmental rank list. Results Thirty-one SLORs (66%) were collected. The SLORs had higher inter-rater reliability for applicant’s qualifications for otolaryngology, global assessment, summary statement, and overall letter ranking. Writer’s background, comparison to contemporaries/predecessors, and letter review ease had higher inter-rater reliability on the NLORs. Mean SLOR rankings were higher for writer’s background (p=0.0007), comparison of applicant to contemporaries/predecessors (p=0.0031), and letter review ease (p<0.0001). Mean SLOR writing time was 4.17±2.18 minutes. Mean ranking time was significantly lower (p<0.0001) for the SLORs (39.24±23.45 seconds) compared to the NLORs (70.95±40.14 seconds). Means of cumulative SLOR scores correlated with our rank list (p=0.004), whereas means of cumulative NLOR scores did not (p=0.18). Means of cumulative NLOR and SLOR scores did not correlate (p=0.26). Conclusions SLORs require little writing time, save reviewing time, and are easier to review compared to NLORs. Our SLOR had higher inter-rater reliability in 4 of 7 categories and was correlated with our rank list. This tool conveys standardized information in an efficient manner. PMID:23172646

  4. "Test" is a Four Letter Word

    Energy Technology Data Exchange (ETDEWEB)

    Pope, G M

    2005-05-03

    For a number of years I had the pleasure of teaching Testing Seminars all over the world and meeting and learning from others in our field. Over a twelve year period, I always asked the following questions to Software Developers, Test Engineers, and Managers who took my two or three day seminar on Software Testing: 'When was the first time you heard the word test'? 'Where were you when you first heard the word test'? 'Who said the word test'? 'How did the word test make you feel'? Most of the thousands of responses were similar to 'It was my third grade teacher at school, and I felt nervous and afraid'. Now there were a few exceptions like 'It was my third grade teacher, and I was happy and excited to show how smart I was'. But by and large, my informal survey found that 'testing' is a word to which most people attach negative meanings, based on its historical context. So why is this important to those of us in the software development business? Because I have found that a preponderance of software developers do not get real excited about hearing that the software they just wrote is going to be 'tested' by the Test Group. Typical reactions I have heard over the years run from: 'I'm sure there is nothing wrong with the software, so go ahead and test it, better you find defects than our customers'. to these extremes: 'There is no need to test my software because there is nothing wrong with it'. 'You are not qualified to test my software because you don't know as much as I do about it'. 'If any Test Engineers come into our office again to test our software we will throw them through the third floor window'. So why is there such a strong negative reaction to testing? It is primitive. It goes back to grade school for many of us. It is a negative word that congers up negative emotions. In other words, 'test' is a four letter word

  5. Biosimilars approval process.

    Science.gov (United States)

    Zuñiga, Leyre; Calvo, Begoña

    2010-04-01

    For similar biological medicinal products, the so-called biosimilars, clinical trials are required rather than just the bioequivalence studies required to support the registration of a generic small molecule drug product. The EU Directive 2001/83/EC, as amended, stated that where a biological medicinal product which is similar to a reference biological product, does not meet the conditions in the definition of generic medicinal products the results of appropriate pre-clinical tests or clinical trials relating to these conditions must be provided. The challenge is to determine the exact nature of the non-clinical and clinical programme required to gain regulatory approval. The applicant is encouraged to provide a detailed description of the strategy used to demonstrate the biosimilar and the reference product have similar profiles in terms of quality, safety and efficacy. The extent to which comparability can be proven will have quite an impact on how many non-clinical and clinical studies the biosimilar applicant will be required to conduct. The dossier submitted by the applicant to the EMEA should cover all aspects of the comparability assessment and must include data on possible unwanted immune reactions to the therapeutic protein. Post-marketing pharmacovigilance plans are also expected to be included in the biosimilar dossier.

  6. A letter signed: the very beginnings of Dalton's atomic theory.

    Science.gov (United States)

    Pratt, Herbert T

    2010-11-01

    This paper explores the provenance and content of a previously unknown personal letter by John Dalton (1766-1844), which is dated 12 April 1803. It relates to a startling breakthrough in Dalton's research, which pre-dates by five months the earliest date in his laboratory notebook, namely, 6 September 1803. The author acquired the letter about thirty years ago, and now offers it to the public. He makes no attempt to explain how it contributes to--or even changes--our understanding of Dalton, but leaves that privilege to Dalton scholars.

  7. Letters of Gold: Enabling Primitive Accumulation through Neoliberal Conservation

    OpenAIRE

    Büscher, Bram

    2009-01-01

    textabstractAbstract: In Capital I, Marx wrote that the history of the separation of the producers from the means of production “is written in the annals of mankind in letters of blood and fire” (Marx, 1976: 875). This ‘so-called primitive accumulation’, or ‘accumulation by dispossession’ in David Harvey’s words, continues unabated. Yet, its framing has changed considerably. Increasingly, capitalists have tried to avoid writing primitive accumulation in ‘letters of blood and fire’. Instead, t...

  8. The medical palimpsest of The Scarlet Letter: an interdisciplinary reading.

    Science.gov (United States)

    Dolezal, J

    2005-06-01

    The multiple historical layers of Roger Chillingworth's character have been overlooked in criticism of The Scarlet Letter. By considering the possible influence of Robert Browning's dramatic poem Paracelsus (1835) on Hawthorne's romance (1850), as well as the ways in which overtones of both herbalism and clinical medicine complicate Chillingworth's character, one rediscovers Chillingworth as Hawthorne's audience likely experienced him: as a fictional palimpsest bearing multiple inscriptions of medical history that reveal an interplay between integrity and corruption. Thus, an interdisciplinary reading of The Scarlet Letter challenges the conventional critical assessment of Chillingworth as a satanic or Faustian figure.

  9. Resource Letter: Research-based Assessments in Physics and Astronomy

    CERN Document Server

    Madsen, Adrian; Sayre, Eleanor C

    2016-01-01

    This resource letter provides a guide to research-based assessments (RBAs) of physics and astronomy content. These are standardized assessments that were rigorously developed and revised using student ideas and interviews, expert input, and statistical analyses. RBAs have had a major impact on physics and astronomy education reform by providing a universal and convincing measure of student understanding that instructors can use to assess and improve the effectiveness of their teaching. In this resource letter, we present an overview of all content RBAs in physics and astronomy by topic, research validation, instructional level, format, and themes, to help faculty find the best assessment for their course.

  10. On the Elements of Tragedy in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    冶静芳

    2014-01-01

    As the masterpiece of Nathaniel Hawthorn’s writing, The Scarlet Letter not only brings him fame forever, but also gives us more about people’s life in Puritan society in 17th. Since this novel is so important and excellent, the thesis mainly focus-es on probing into the theme of elements of tragedy in The Scarlet Letter. According to the whole story, the love tragedy is attrib-uted to four factors: the Puritan beliefs of original sin, the attitude of public on love outside marriage, the personalities of the main characters, and the differences between dream and reality.

  11. An Analysis of the Symbolic Colors in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    ZHU Kai-lin

    2016-01-01

    Nathaniel Hawthorn is the greatest American romantic novelist during the nineteenth century. He is skillful at the using of symbolism in his works, especially in his masterpiece The Scarlet Letter. Hawthorn is a writer with art talent, who uses differ-ent colors to enhance the artistic effects of The scarlet Letter. Colors emerging on the most occasions are used as a mayor form of symbolism to reflect the character’s feelings, personalities and fates. This paper aims to elaborate the usage of colors as a form of symbolism in three parts:the symbolic meaning of red, the symbolic meaning of black, and the symbolic meaning of grey.

  12. Resource Letter SOP-1: Self-Organizing Physics

    Science.gov (United States)

    Jacobs, Donald T.

    2015-08-01

    This Resource Letter introduces the reader to an area of physics where systems can self-organize to a particular shape or behavior that, while dynamically changing, is surprisingly robust. The self-organization is due to the complex interactions that typically preclude explanation from just the forces among adjacent molecules or objects. How one recognizes such systems and explains their behavior is the topic of this Resource Letter. Some systems exhibit universal behavior that is well documented and understood, but other systems are just now being investigated.

  13. Dear Hacker Letters to the Editor of 2600

    CERN Document Server

    Goldstein, Emmanuel

    2010-01-01

    Actual letters written to the leading hackers' magazine. For 25 years, 2600: The Hacker Quarterly has given voice to the hacker community in all its manifestations. This collection of letters to the magazine reveals the thoughts and viewpoints of hackers, both white and black hat, as well as hacker wannabes, technophiles, and people concerned about computer security. Insightful and entertaining, the exchanges illustrate 2600 's vast readership, from teenage rebels, anarchists, and survivalists to law enforcement, consumer advocates, and worried parents.: 2600: The Hacker Quarterly has been the

  14. Drugs Approved for Stomach (Gastric) Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Stomach (Gastric) Cancer This page lists cancer drugs approved ... that are not listed here. Drugs Approved for Stomach (Gastric) Cancer Cyramza (Ramucirumab) Docetaxel Doxorubicin Hydrochloride 5- ...

  15. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Types of respirators to be approved; scope of... Classification of Approved Respirators; Scope of Approval; Atmospheric Hazards; Service Time § 84.50 Types of respirators to be approved; scope of approval. Approvals shall be issued for the types of respirators...

  16. Effects of ocular transverse chromatic aberration on near foveal letter recognition.

    Science.gov (United States)

    Yang, Shun-nan; Tai, Yu-chi; Laukkanen, Hannu; Sheedy, James

    2009-11-01

    Transverse chromatic aberration (TCA) smears retinal images of peripheral stimuli. In reading, text information is extracted from both foveal and near fovea, where TCA magnitude is relatively small and variable. The present study investigated whether TCA significantly affects near foveal letter identification. Subjects were briefly presented a string of five letters centered one degree of visual angle to the left or right of fixation. They indicated whether the middle letter was the same as a comparison letter subsequently presented. Letter strings were rendered with a reddish fringe on the left edge of each letter and a bluish fringe on the right edge, consistent with expected left periphery TCA, or with the opposite fringe consistent with expected right periphery TCA. Effect of the color fringing on letter recognition was measured by comparing the response accuracy for fringed and non-fringed stimuli. Effects of lateral interference were examined by manipulating inter-letter spacing and similarity of neighboring letters. Results demonstrated significantly improved response accuracy with the color fringe opposite to the expected TCA, but decreased accuracy when consistent with it. Narrower letter spacing exacerbated the effect of the color fringe, whereas letter similarity did not. Our results suggest that TCA significantly reduces the ability to recognize letters in the near fovea by impeding recognition of individual letters and by enhancing lateral interference between letters.

  17. Contributions of Emergent Literacy Skills to Name Writing, Letter Writing, and Spelling in Preschool Children

    Science.gov (United States)

    Puranik, Cynthia S.; Lonigan, Christopher J.; Kim, Young-Suk

    2011-01-01

    The purpose of this study was to examine which emergent literacy skills contribute to preschool children’s emergent writing (name-writing, letter-writing, and spelling) skills. Emergent reading and writing tasks were administered to 296 preschool children aged 4–5 years. Print knowledge and letter-writing skills made positive contributions to name writing; whereas alphabet knowledge, print knowledge, and name writing made positive contributions to letter writing. Both name-writing and letter-writing skills made significant contributions to the prediction of spelling after controlling for age, parental education, print knowledge, phonological awareness, and letter-name and letter-sound knowledge; however, only letter-writing abilities made a significant unique contribution to the prediction of spelling when both letter-writing and name-writing skills were considered together. Name writing reflects knowledge of some letters rather than a broader knowledge of letters that may be needed to support early spelling. Children’s letter-writing skills may be a better indicator of children’s emergent literacy and developing spelling skills than are their name-writing skills at the end of the preschool year. Spelling is a developmentally complex skill beginning in preschool and includes letter writing and blending skills, print knowledge, and letter-name and letter-sound knowledge. PMID:21927537

  18. Approval plans issues and innovations

    CERN Document Server

    Katz, Linda S

    2013-01-01

    How can you, as an acquisition librarians, keep current on the output of hundreds of publishers? The answer, of course, is that you cannot. For over 30 years, approval plans have been used by librarians to acquire current titles, save staff time, and build core collections. Even today, these reasons seem appropriate, as libraries try to maintain up-to-date collections and control personnel and operating budgets. However, as shown in Approval Plans: Issues and Innovations, the use of approval plans is not so simple and straightforward; their use is subject to complex procedures and policies--an

  19. NWS Corrections to Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Form B-14 is the National Weather Service form entitled 'Notice of Corrections to Weather Records.' The forms are used to make corrections to observations on forms...

  20. Visual and Artistic Functions of Letters Khaghani’s Poetry

    Directory of Open Access Journals (Sweden)

    Dr. M. Zolfaghari

    Full Text Available The intensity of emotion and vibration of meaning in the poet's mind causes him to go beyond the ordinary language and through metaphors, similes and linguistic preparation he conveys intellectual and emotional meanings. He has a sharp eye and a sensitive spirit and creative temprement and by inventing new images shows the creativity and imagination in various arenas and attempts in the way of literary strength and creating personal style and this point more than anything else must be done by presenting images and newness. Perhaps in the sixth century, and especially in Azerbaijani school, more than other periods, poets have been looking for creating innovative style in eloquence. Their major attempts were mainly in imaging, it was a wide field that they have competed and it is natural that in this illustration the alphabet letters would be very helpful. Khaghani poetry as one of the greatest poets of this school has the perfect poetrical book of painting and meaning, and delicated pattern in new and different scientific, cultural and religious paintings and letters are a broad range of elements that put a new field in front of the poet and he is aware of the potential features of the letters and also the new images and the artistic creativity.This paper shows descriptive - analytical study of various aspects of Khaghani’s poetry and frequency of letters in the alphabet, authentic images based on alphabet, taken at different pseudo relevance of poetry in the context of multiple semantic and literal characters, making figures of speech based on literary characters, images and characters and the sense of connection . . . which has been shown in his poetry.Letter has double and even multiple uses in Khaghani poetic works (divan and more than the construction of words which is the real and common sense that is used as an artistic. There is a world in the heart of every letter, word and morpheme lies in the poet's point of view is the last and

  1. How do we code the letters of a word when we have to write it? Investigating double letter representation in French.

    Science.gov (United States)

    Kandel, Sonia; Peereman, Ronald; Ghimenton, Anna

    2014-05-01

    How do we code the letters of a word when we have to write it? We examined whether the orthographic representations that the writing system activates have a specific coding for letters when these are doubled in a word. French participants wrote words on a digitizer. The word pairs shared the initial letters and differed on the presence of a double letter (e.g., LISSER/LISTER). The results on latencies, letter and inter-letter interval durations revealed that L and I are slower to write when followed by a doublet (SS) than when not (ST). Doublet processing constitutes a supplementary cognitive load that delays word production. This suggests that word representations code letter identity and quantity separately. The data also revealed that the central processes that are involved in spelling representation cascade into the peripheral processes that regulate movement execution.

  2. 76 FR 79701 - Bristol-Myers Squibb Co. et al.; Withdrawal of Approval of 70 New Drug Applications and 97...

    Science.gov (United States)

    2011-12-22

    ... 70 New Drug Applications and 97 Abbreviated New Drug Applications; Correction AGENCY: Food and Drug... withdrawal of approval of 70 new drug applications (NDAs) and 97 abbreviated new drug applications...

  3. Error Correction in Classroom

    Institute of Scientific and Technical Information of China (English)

    Dr. Grace Zhang

    2000-01-01

    Error correction is an important issue in foreign language acquisition. This paper investigates how students feel about the way in which error correction should take place in a Chinese-as-a foreign-language classroom, based on empirical data of a large scale. The study shows that there is a general consensus that error correction is necessary. In terms of correction strategy, the students preferred a combination of direct and indirect corrections, or a direct only correction. The former choice indicates that students would be happy to take either so long as the correction gets done.Most students didn't mind peer correcting provided it is conducted in a constructive way. More than halfofthe students would feel uncomfortable ifthe same error they make in class is corrected consecutively more than three times. Taking these findings into consideration, we may want to cncourage peer correcting, use a combination of correction strategies (direct only if suitable) and do it in a non-threatening and sensitive way. It is hoped that this study would contribute to the effectiveness of error correction in a Chinese language classroom and it may also have a wider implication on other languages.

  4. Analytic corrections to AdS by scalar matter and curvature squared term

    CERN Document Server

    Joshi, Lata Kh

    2016-01-01

    We revisit the background solution for scalar matter coupled higher derivative gravity originally reported in arXiv: 1409.8019[hep-th]. In this letter, we choose a convenient ansatz for metric which determines the first order perturbative corrections to scalar as well as geometry.

  5. A Mentoring Opportunity: A Joint Effort in Writing Letters of Recommendation.

    Science.gov (United States)

    Master, Zubin

    2017-01-01

    Integrity in writing letters of recommendation is important to academic research because it is an influential criterion used pervasively in peer review. While research in the integrity of recommendation letters has concentrated on contents of the letter, bias, and reliability, few have questioned the process of letter writing. Here, I argue that letter writing should be a joint opportunity between mentor/supervisor/advisor and trainee. It results in more compelling letters, may prevent errors and the use of biased language, and serves as an excellent mentoring opportunity promoting self-reflection.

  6. From word superiority to word inferiority: Visual processing of letters and words in pure alexia

    DEFF Research Database (Denmark)

    Habekost, Thomas; Petersen, Anders; Behrmann, Marlene

    2014-01-01

    tasks for all patients, and this pattern was more pronounced in the more severely affected patients. The relationship between performance with single letters and words was, however, not straightforward: One patient performed within the normal range on the letter perception task, while being severely...... impaired in letter naming and word processing, and performance with letters and words was dissociated in all four patients, with word reading being more severely impaired than letter recognition. This suggests that the word reading deficit in pure alexia may not be reduced to an impairment in single letter...

  7. Teaching sound letter correspondence and consonant-vowel-consonant combinations to young children who use augmentative and alternative communication.

    Science.gov (United States)

    Johnston, Susan S; Davenport, Lisa; Kanarowski, Betsy; Rhodehouse, Sara; McDonnell, Andrea P

    2009-06-01

    The purpose of this study was to provide a preliminary examination of an intervention strategy designed to teach sound-letter correspondence and spelling of consonant-vowel-consonant (CVC) combinations to young children who use Augmentative and Alternative Communication (AAC). A multiple baseline probe design across behaviors was used to assess the effects of the intervention on the percentage of correct responses provided by two participants on the target skills during free-choice play activities in the literacy center of inclusive classrooms. The results of this study provide preliminary support for the use of the intervention strategy within inclusive classrooms.

  8. Electronic Voucher Approval - Financial Management

    Data.gov (United States)

    US Agency for International Development — This process provides a workflow and eSignature capability which allows the CFO to router vouchers for review and electronic signature approval to COTRs in AIDW. It...

  9. Mavyret Approved for Hepatitis C

    Science.gov (United States)

    ... news/fullstory_167618.html Mavyret Approved for Hepatitis C A chronic viral infection of the liver To ... treat adults with certain types of chronic hepatitis C virus (HCV). The combination drug is the first ...

  10. Drugs Approved for Wilms Tumor

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Wilms tumor and other childhood kidney cancers. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  11. Elosulfase alfa: first global approval.

    Science.gov (United States)

    Sanford, Mark; Lo, Jin Han

    2014-04-01

    Elosulfase alfa (Vimizim™) is a recombinant form of N-acetylgalactosamine-6-sulfatase (GALNS) that was developed by BioMarin Pharmaceutical Inc. as an enzyme replacement therapy for patients with mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome. Patients with MPS IVA have a GALNS deficiency, which results in serious musculoskeletal, cardiorespiratory and other system disturbances. Elosulfase alfa was approved by the US FDA on 14 February 2014 for the treatment of MPS IVA. The European Medicines Agency Committee for Medicinal Products for Human Use (CHMP) has recently recommended that elosulfase alfa be approved for use in the EU in the same indication. Within the last year, the manufacturer has also filed applications for approval for the use of elosulfase alfa in MPS IVA in Brazil, Australia, Canada and Mexico. This article summarizes the milestones in the development of elosulfase alfa leading to its first global approval in MPS IVA.

  12. Is It Really FDA Approved?

    Science.gov (United States)

    ... must be proven safe and effective to FDA’s satisfaction before companies can market them in interstate commerce. ... product to market. back to top FDA approves food additives in food for people. Although FDA does ...

  13. Drugs Approved for Liver Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for liver cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  14. Drugs Approved for Vulvar Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for vulvar cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  15. Drugs Approved for Esophageal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for esophageal cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  16. Drugs Approved for Vaginal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) to prevent vaginal cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  17. Drugs Approved for Endometrial Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for endometrial cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  18. Drugs Approved for Penile Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for penile cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  19. Drugs Approved for Kaposi Sarcoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Kaposi sarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  20. Drugs Approved for Bone Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bone cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  1. Drugs Approved for Prostate Cancer

    Science.gov (United States)

    ... 2015 2014 2013 2012 Media Resources Media Contacts Multicultural ... This page lists cancer drugs approved by the Food and Drug Administration (FDA) for prostate cancer. The list includes generic ...

  2. Trulance Approved for Chronic Constipation

    Science.gov (United States)

    ... news/fullstory_163171.html Trulance Approved for Chronic Constipation Drug designed to stimulate upper gastrointestinal tract To ... U.S. Food and Drug Administration to treat persistent constipation of unknown (idiopathic) cause in adults. Some 42 ...

  3. Discrimination of approved drugs from experimental drugs by learning methods

    Directory of Open Access Journals (Sweden)

    Li Yixue

    2011-05-01

    Full Text Available Abstract Background To assess whether a compound is druglike or not as early as possible is always critical in drug discovery process. There have been many efforts made to create sets of 'rules' or 'filters' which, it is hoped, will help chemists to identify 'drug-like' molecules from 'non-drug' molecules. However, among the chemical space of the druglike molecules, the minority will be approved drugs. Classifying approved drugs from experimental drugs may be more helpful to obtain future approved drugs. Therefore, discrimination of approved drugs from experimental ones has been done in this paper by analyzing the compounds in terms of existing drugs features and machine learning methods. Results Four methodologies were compared by their performance to classify approved drugs from experimental ones. The best results were obtained by SVM, in which the accuracy is 0.7911, the sensitivity is 0.5929, and the specificity is 0.8743. Based on the results, consensus model was developed to effectively discriminate drugs, which further pushed the correct classification rate up to 0.8517, sensitivity up to 0.7242, specificity up to 0.9352. The applications on the Traditional Chinese Medicine Ingredients Database (TCM-ID tested the methods. Therefore this model has been proven to be a potent tool for identifying drug molecules. Conclusion The studies would have potential applications in the research of combinatorial library design and virtual high throughput screening for drug discovery.

  4. Adolescent Suidice--An Open Letter to Counselors.

    Science.gov (United States)

    Wolfe, Jane

    1988-01-01

    A mother of a 16 year-old suicide victim writes to school counselors who let her down by not informing her of important changes in her son's activities, personality, and choice of friends at school. The letter also addresses two psychologists in a psychiatric hospital who suppressed information about the boy's suicidal intentions and his…

  5. Letters from a suicide: Van Gogh and his sister.

    Science.gov (United States)

    Lester, David

    2010-04-01

    An analysis of trends over a 3-yr. period in the letters of Vincent Van Gogh to his sister as the time of his suicide approached identified 8 trends, including an increase in words concerned with anxiety and words concerned with the past.

  6. Research on the Attitude towards Lettered-words in Chinese

    Institute of Scientific and Technical Information of China (English)

    潘正华

    2014-01-01

    Lettered words have sprouted in all kinds of situations and many kinds of media, which has been a very common phenomenon. This essay focuses on the relationship between the attitudes and the factors such as age, sex, and the educational background, trying to find some correlation between them, which is important also in the language policy.

  7. Cold-induced vasodilation : letter to the editor

    NARCIS (Netherlands)

    Daanen, H.A.M.

    2009-01-01

    Reactie op: Flouris, et al. Effect of body temperature on cold induced vasodilationa. Eur J Applied Phys 2008;104:491-499. De aurteurs hebben daar weer een reply op geschreven; Flouris AD, Cheung SS (2009) Authors’ response to H. Daanen’s ‘cold-induced vasodilation’ letter. Eur J Appl Physiol 106:31

  8. 75 FR 12123 - Restrictions on Private Carriage of Letters

    Science.gov (United States)

    2010-03-15

    ... From the Federal Register Online via the Government Publishing Office POSTAL SERVICE 39 CFR Parts 310 and 320 Restrictions on Private Carriage of Letters AGENCY: Postal Service TM ACTION: Final rule. SUMMARY: This rule amends the Postal Service regulations on the enforcement and suspension of the Private...

  9. SPS Research into superconductivity highlighted in Physical Review Letters

    OpenAIRE

    2016-01-01

    Research conducted by Dr Jorge Quintanilla as part of an international collaboration has been chosen as an Editors' Suggestion on the Physical Review Letters website. The full article can be accessed here. Below is a summary from Dr Quintanilla about what the research was and how it is useful.

  10. The Effects of Sin in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    吴希博; 逯海涛

    2008-01-01

    "Sin" plays a very important role in the understanding of Hawthorne's "psychological romance"- The Scarlet Letter. The paper introduces the major view that influences him--the Puritan doctrine of "original sin" so as to investigate Hawthorne's own attitudes towards the sin and the effects of sin on the two main characters in the novel.

  11. RL-PER1: Resource Letter on Physics Education Research.

    Science.gov (United States)

    McDermott, Lillian C.; Redish, Edward F.

    The purpose of this resource letter is to provide an overview of research on the learning and teaching of physics. The references have been selected to meet the needs of two groups of physicists engaged in physics education. The first is the growing number whose field of scholarly inquiry is (or might become) physics education research. The second…

  12. Resource Letter PhD-1: Physics Demonstrations.

    Science.gov (United States)

    Davis, John A.; Eaton, Bruce G.

    1979-01-01

    This resource letter is an annotated bibliography aimed at individuals who have recently become interested in lecture demonstrations in physics. Listed are 103 printed sources of information on lecture demonstrations. Whenever possible, annotations are followed by reviews so that other opinions can be consulted. (BT)

  13. Letters Home as an Alternative to Lab Reports

    Science.gov (United States)

    Lane, W. Brian

    2014-01-01

    The traditional lab report is known to create several pedagogical shortcomings in the introductory physics course, particularly with regard to promoting student engagement and encouraging quality writing. This paper discusses the use of a "letter home" written to a non-physicist as an alternative to lab reports that creates a more…

  14. Resource Letter TPB-1: Theoretical Physics and Biology

    Science.gov (United States)

    MacDonald, N.

    1974-01-01

    This is one of a series of Resource Letters on different topics, intended to guide college physicists to some of the literature and other teaching aids. This bibliography is designed to help physicists identify literature related to mathematical biology. (Author/RH)

  15. Authors' response to the letter from Kalleian Eserian et al

    NARCIS (Netherlands)

    Riet-Nales, D.A. van; Doeve, M.E.; Nicia, A.E.; Teerenstra, S.; Notenboom, K.; Hekster, Y.A.; Bemt, B.J.F van den

    2015-01-01

    This letter is a response to the comments of Kalleian Eserian et al. on our study relating to the accuracy, precision and sustainability of six tablet splitters and a kitchen knife as an alternative to breaking paracetamol 500mg tablets by hand. We would like to inform the readers of International J

  16. The letter of submission: avoiding the promotional genre

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    1998-01-01

    Functionally the letter of submission accompanying an article submitted to a journal is promotional, but it does not have the form one would expect from e.g. Bhatia 1993. Instead it is extremely brief and uninformative. This reflects the so-called Utilitarian Discourse which is a shared feature...

  17. The Greek lead letter from Ruscino (Languedoc, France

    Directory of Open Access Journals (Sweden)

    Isabelle Rébé

    2017-09-01

    Full Text Available A new lead tablet with Greek text, possibly a letter from the 4th c. BC, is published here. The edition and partial translation is accompanied by a chronological, paleographic and linguistic study, and a comment that includes some hypotheses about its interpretation within this special genre of documents, whose number and significance are continuously increasing.

  18. Relations among Early Object Recognition Skills: Objects and Letters

    Science.gov (United States)

    Augustine, Elaine; Jones, Susan S.; Smith, Linda B.; Longfield, Erica

    2015-01-01

    Human visual object recognition is multifaceted and comprised of several domains of expertise. Developmental relations between young children's letter recognition and their 3-dimensional object recognition abilities are implicated on several grounds but have received little research attention. Here, we ask how preschoolers' success in recognizing…

  19. Transposed-Letter Priming across Inflectional Morpheme Boundaries

    Science.gov (United States)

    Zargar, Ehsan Shafiee; Witzel, Naoko

    2017-01-01

    This study reports findings from two experiments testing whether a transposed-letter (TL) priming effect can be obtained when the transposition occurs across morphological boundaries. Previous studies have primarily tested derivationally complex words or compound words, but have not examined a more rule-based and productive morphological…

  20. Functional communication within a perceptual network processing letters and pseudoletters.

    Science.gov (United States)

    Herdman, Anthony T

    2011-10-01

    Many studies have identified regions within human ventral visual stream to be important for object identification and categorization; however, knowledge of how perceptual information is communicated within the visual network is still limited. Current theories posit that if a high correspondence between incoming sensory information and internal representations exists, then the object is rapidly identified, and if there is not, then the object requires extra detailed processing. Event-related responses from the present magnetoencephalography study showed two main effects. The N1m peak latencies were approximately 15 milliseconds earlier to familiar letters than to unfamiliar pseudoletters, and the N2m was more negative to pseudoletters than to letters. Event-related beamforming analyses identified these effects to be within bilateral visual cortices with a right lateralization for the N2m effect. Furthermore, functional connectivity analyses revealed that gamma-band (50-80 Hz) oscillatory phase synchronizations among occipital regions were greater to letters than to pseudoletters (around 85 milliseconds). However, during a later time interval between 245 and 375 milliseconds, pseudoletters elicited greater gamma-band phase synchronizations among a more distributed occipital network than did letters. These findings indicate that familiar object processing begins by at least 85 milliseconds, which could represent an initial match to an internal template. In addition, unfamiliar object processing persisted longer than that for familiar objects, which could reflect greater attention to inexperienced objects to determine their identity and/or to consolidate a new template to aid in future identification.

  1. Syllable and Letter Knowledge in Early Korean Hangul Reading

    Science.gov (United States)

    Cho, Jeung-Ryeul

    2009-01-01

    This study examined the development of Korean consonant-vowel (CV) syllable identification, consonant and vowel letter knowledge, and their relationships to phonological awareness and the reading of regular Hangul words among Korean kindergartners as a 6-month longitudinal study. Results showed that Korean children identified CV syllables better…

  2. Repeated Reading Intervention Effects in Kindergartners with Partial Letter Knowledge

    Science.gov (United States)

    van Gorp, Karly; Segers, Eliane; Verhoeven, Ludo

    2014-01-01

    The direct, transfer and retention effects of a repeated reading intervention study of single CVC (consonant in the onset and a vowel and consonant in the rime) words in kindergartners with partial letter knowledge were examined. A total of 26 second-year kindergartners participated in this study. Participants were divided over two feedback…

  3. 26 CFR 601.201 - Rulings and determinations letters.

    Science.gov (United States)

    2010-04-01

    ... not merely incorporated by reference, and must be accompanied by an analysis of their bearing on the... requirements for establishing that translations of foreign law are satisfactory as evidence for purposes of... taxpayer believes that a determination letter of this type is in error, he may ask the district director...

  4. Army Response Letter & Analysis - signed January 19, 2001

    Science.gov (United States)

    A response to the letter, which requested a review of the proposed decision by the Army Corps of Engineers Baltimore District to issue four Department of the Army permits to Baltimore County (3 permits) and Anne Arundel County (1 permit), MD.

  5. A Letter from a Black Mom to Her Son

    Science.gov (United States)

    Watson, Dyan

    2012-01-01

    An African American mother and teacher educator uses examples from her own childhood to describe how she hopes her child will be treated by teachers, and what she fears. In her letter to her son, the African American mom expresses how she want teachers to know her son's journey to school--metaphorically and physically. She wants them to know that…

  6. 33 CFR 157.204 - Letter of acceptance.

    Science.gov (United States)

    2010-07-01

    ...) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.204 Letter of acceptance. The Coast Guard... submitted under § 157.202 show that the dedicated clean ballast tank system meets this subpart....

  7. The Psychological Reflection of Hawthorn in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    SHI Yan-qing

    2015-01-01

    The Scarlet Letter is Nathaniel Hawthorne’s masterpiece, representing the height of Hawthorne’s literary genius. This thesis tries to reveal part of the author’s psychological activities, repressed feelings from his childhood from analyzing the main characters, especially Hester, the mother and Pearl, the daughter.

  8. A Cohesive and Coherent Analysis of The Purloined Letter

    Institute of Scientific and Technical Information of China (English)

    杜娟娟; 郭鸿雁

    2013-01-01

      The thesis aims to do a research on the cohesion and coherence in The Purloined Letter written by Edgar Allan Poe based on the theories of Halliday and Hasan as well as the Chinese scholars Zhang Delu and Liu Rushan. By the means of them, Poe’s ingenious composition and vivid characters emerge in the mind of the readers.

  9. Model business letters, emails and other business documents

    CERN Document Server

    Taylor, Shirley

    2012-01-01

    For anyone who wants to communicate effectively in business, this is your complete reference guide for any form of written communication. Packed with over 500 sample documents, over 100 tips for better business writing and useful templates you can apply to your writing immediately, Model Business Letters will help you put the key rules of good business writing into action.

  10. Underlying Cause(s) of Letter Perseveration Errors

    Science.gov (United States)

    Fischer-Baum, Simon; Rapp, Brenda

    2012-01-01

    Perseverations, the inappropriate intrusion of elements from a previous response into a current response, are commonly observed in individuals with acquired deficits. This study specifically investigates the contribution of failure-to activate and failure-to-inhibit deficit(s) in the generation of letter perseveration errors in acquired…

  11. 33 CFR 401.68 - Explosives Permission Letter.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Explosives Permission Letter. 401.68 Section 401.68 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Dangerous Cargo § 401.68...

  12. Discourse Strategies of Italian and English Sales Promotion Letters

    Science.gov (United States)

    Vergaro, Carla

    2004-01-01

    This article describes a contrastive study on rhetorical differences between Italian and English sales promotion letters. It is assumed that cultural differences affect discourse genres traditionally considered as standardized, ritual or even formulaic, written business communication being a case in point. It was our goal to investigate how…

  13. Resource Letter FNP-1: Frontiers of nuclear physics

    Science.gov (United States)

    Bertsch, G. F.

    2004-08-01

    This Resource Letter provides a bibliography of the current research activities in nuclear physics and also a guide for finding useful nuclear data. The major areas included are nuclear structure and reactions, symmetry tests, nuclear astrophysics, nuclear theory, high-density matter, and nuclear instrumentation.

  14. Breaking the Genetic Code in a Letter by Max Delbruck.

    Science.gov (United States)

    Fox, Marty

    1996-01-01

    Describes a classroom exercise that uses a letter from Max Delbruck to George Beadle to stimulate interest in the mechanics of a nonoverlapping comma-free code. Enables students to participate in the rich history of molecular biology and illustrates to them that scientists and science can be fun. (JRH)

  15. Letters of Gold: Enabling Primitive Accumulation through Neoliberal Conservation

    NARCIS (Netherlands)

    B.E. Büscher (Bram)

    2009-01-01

    textabstractAbstract: In Capital I, Marx wrote that the history of the separation of the producers from the means of production “is written in the annals of mankind in letters of blood and fire” (Marx, 1976: 875). This ‘so-called primitive accumulation’, or ‘accumulation by dispossession’ in David H

  16. Friday Letters: Connecting Students, Teachers, and Families through Writing

    Science.gov (United States)

    Newman, Terry H.; Bizzarri, Sarah A.

    2012-01-01

    An important part of student success in school is the involvement of families. However, the communication between students and families regarding school is often sparse at best and caregivers can feel left out as to what is happening. Friday letters improve communication between students and families and also provide a myriad of instructional…

  17. Grooming the Victim: An Analysis of a Perpetrator's Seduction Letter.

    Science.gov (United States)

    Singer, Mark I.; And Others

    1992-01-01

    This paper reviews the literature on the sexual victimization of adolescent males, with emphasis on victim selection factors and strategies. A letter written by a middle-aged man to entice a teenage boy into sexual activity is then presented and analyzed. (DB)

  18. On the Entropy and Letter Frequencies of Powerfree Words

    Directory of Open Access Journals (Sweden)

    Manuela Heuer

    2008-11-01

    Full Text Available We review the recent progress in the investigation of powerfree words, with particular emphasis on binary cubefree and ternary squarefree words. Besides various bounds on the entropy, we provide bounds on letter frequencies and consider their empirical distribution obtained by an enumeration of binary cubefree words up to length 80.

  19. Just keep it simple : a field experiment on fundraising letters

    NARCIS (Netherlands)

    Bekkers, René; Crutzen, Olaf

    2007-01-01

    This paper studies how the use of a colour picture in fundraising letters affect response rates and the amount donated in a fundraising campaign. Envelopes, with a full colour picture were tested against envelopes, without a picture in a controlled field experiment at a national religious charity in

  20. Tactile Perception and Braille Letter Recognition: Effects of Developmental Teaching.

    Science.gov (United States)

    Mangold, Sally S.

    1978-01-01

    The extent to which a developmental program of tactile perception and braille letter recognition would affect errors in these abilities and reduce scrubbing and backtracking behaviors of 30 legally blind braille users (5-15 years old) was studied. (Author/BD)