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Sample records for corpus christi tx

  1. 76 FR 18395 - Safety Zone; Naval Air Station Corpus Christi Air Show, Oso Bay, Corpus Christi, TX

    Science.gov (United States)

    2011-04-04

    ...-AA00 Safety Zone; Naval Air Station Corpus Christi Air Show, Oso Bay, Corpus Christi, TX AGENCY: Coast... zone on the navigable waters of Oso Bay in Corpus Christi, Texas in support of the 2011 Naval Air... entities and very few recreational fisherman utilize this section of Oso Bay, the restriction of vessel...

  2. 75 FR 31677 - Amendment of Class E Airspace; Corpus Christi, TX

    Science.gov (United States)

    2010-06-04

    ... Jose Island Airport, TX (Lat. 27[deg]56'40'' N., long. 96[deg]59'06'' W.) Rockport, Aransas County... Meacham Blvd., Fort Worth, TX 76137; telephone (817) 321- 7716. SUPPLEMENTARY INFORMATION: History On... Corpus Christi, TX [Amended] Corpus Christi International Airport, TX (Lat. 27[deg]46'13'' N., long. 97...

  3. 75 FR 66301 - Amendment of Class E Airspace; Corpus Christi, TX

    Science.gov (United States)

    2010-10-28

    ..., TX (Lat. 27[deg]48'43'' N., long. 97[deg]05'20'' W.) Rockport, San Jose Island Airport, TX (Lat. 27... Meacham Blvd., Fort Worth, TX 76137; telephone (817) 321- 7716. SUPPLEMENTARY INFORMATION: History On July... Christi International Airport, TX (Lat. 27[deg]46'13'' N., long. 97[deg]30'04'' W.) Corpus Christi NAS...

  4. 33 CFR 165.808 - Corpus Christi Ship Channel, Corpus Christi, TX, safety zone.

    Science.gov (United States)

    2010-07-01

    ... Petroleum Gas, the waters within a 500 yard radius of the LPG carrier while the vessel transits the Corpus Christi Ship Channel to the LPG receiving facility. The safety zone remains in effect until the LPG vessel is moored at the LPG receiving facility. (2) For outgoing tank vessels loaded with LPG, the waters...

  5. CORPUS CHRISTI E A FOME NO MUNDO

    Directory of Open Access Journals (Sweden)

    Carlos Alberto dos Santos Dutra

    1995-01-01

    Full Text Available A festa religiosa de Corpus Christi, data da instituição da Eucaristia, neste ano foi comemorada no dia 15 de junho. Neste sacramento, entende a Igreja católica, o próprio Cristo se comunica para nutrir e salvar o homem. Expressão e síntese do cristianismo, é a identificação do sacrifício de Cristo com o sacrifício do homem.

  6. Investigation of ground-water contamination at a drainage ditch, Installation Restoration Site 4, Naval Air Station Corpus Christi, Corpus Christi, Texas, 2005–06

    Science.gov (United States)

    Vroblesky, Don A.; Casey, Clifton C.

    2007-01-01

    The U.S. Geological Survey, in cooperation with the Naval Facilities Engineering Command Southeast, used newly developed sampling methods to investigate ground-water contamination by chlorobenzenes beneath a drainage ditch on the southwestern side of Installation Restoration Site 4, Naval Air Station Corpus Christi, Corpus Christi, Texas, during 2005-06. The drainage ditch, which is a potential receptor for ground-water contaminants from Installation Restoration Site 4, intermittently discharges water to Corpus Christi Bay. This report uses data from a new type of pore-water sampler developed for this investigation and other methods to examine the subsurface contamination beneath the drainage ditch. Analysis of ground water from the samplers indicated that chlorobenzenes (maximum detected concentration of 160 micrograms per liter) are present in the ground water beneath the ditch. The concentrations of dissolved oxygen in the samples (less than 0.05-0.4 milligram per liter) showed that the ground water beneath and near the ditch is anaerobic, indicating that substantial chlorobenzene biodegradation in the aquifer beneath the ditch is unlikely. Probable alternative mechanisms of chlorobenzene removal in the ground water beneath the drainage ditch include sorption onto the organic-rich sediment and contaminant depletion by cattails through uptake, sorption, and localized soil aeration.

  7. Flow and Suspended Sediment Events in the Near-Coastal Zone off Corpus Christi, Texas

    Science.gov (United States)

    2003-09-30

    redistribution of preexisting shelf sediments during storms and (2) transportation of suspended sediment from the adjacent bay- lagoon system. Snedden et al...and K.E. Schmedes. (1983). Submerged lands of Texas, Corpus Christi area: sediments, geochemistry, benthic macroinvertebrates and associated

  8. Draft Site Management and Monitoring Plan for Corpus Christi Maintenance and New Work Ocean Dredged Material Disposal Site

    Science.gov (United States)

    USEPA Region 6 and the US Army Corps of Engineers submit for public comment the Draft Site Management and Monitoring Plan for Corpus Christi Maintenance and New Work Ocean Dredged Material Disposal Site

  9. Musculoskeletal Fitness Measures Are Not Created Equal: An Assessment of School Children in Corpus Christi, Texas

    OpenAIRE

    Toyin Ajisafe; Theresa Garcia; Hsin-Chen Fanchiang

    2018-01-01

    This study investigated current obesity prevalence and associations between musculoskeletal fitness test scores and the odds of being underweight, overweight, or obese compared to having a healthy weight in elementary school children in Corpus Christi, Texas. The sample analyzed consisted of 492 public elementary school children between kindergarten and fifth grade. Their ages ranged from 5 to 11 years. Trunk lift, 90° push-up, curl-up, and back saver sit and reach tests were administered. We...

  10. Musculoskeletal Fitness Measures Are Not Created Equal: An Assessment of School Children in Corpus Christi, Texas.

    Science.gov (United States)

    Ajisafe, Toyin; Garcia, Theresa; Fanchiang, Hsin-Chen

    2018-01-01

    This study investigated current obesity prevalence and associations between musculoskeletal fitness test scores and the odds of being underweight, overweight, or obese compared to having a healthy weight in elementary school children in Corpus Christi, Texas. The sample analyzed consisted of 492 public elementary school children between kindergarten and fifth grade. Their ages ranged from 5 to 11 years. Trunk lift, 90° push-up, curl-up, and back saver sit and reach tests were administered. Weight status was determined using BMI scores and the CDC growth charts. Obesity prevalence remains high among elementary school-aged children in Corpus Christi, Texas. Higher 90° push-up test scores were most consistently associated with decreased odds of being obese as compared to being overweight and having healthy weight except in kindergarten. Conversely, higher trunk lift test scores were associated with increased odds of being obese in second and fourth grades. When children achieved the minimum score to be classified in the Healthy Fitness Zone, those with healthy weight had similarly low musculoskeletal fitness (i.e., abdominal strength and endurance, hamstring flexibility, and trunk extensor strength and flexibility) as peers with overweight and obesity, especially in the lower grades. It was concluded that increased obesity prevalence in higher grades may be precipitated (at least in part) by low musculoskeletal fitness in the lower grades, especially kindergarten. Given previous associations in the literature, low musculoskeletal fitness may be symptomatic of poor motor skill competence in the current sample. These findings suggest a need for early and focused school-based interventions that leverage both known and novel strategies to combat pediatric obesity in Corpus Christi.

  11. Musculoskeletal Fitness Measures Are Not Created Equal: An Assessment of School Children in Corpus Christi, Texas

    Directory of Open Access Journals (Sweden)

    Toyin Ajisafe

    2018-05-01

    Full Text Available This study investigated current obesity prevalence and associations between musculoskeletal fitness test scores and the odds of being underweight, overweight, or obese compared to having a healthy weight in elementary school children in Corpus Christi, Texas. The sample analyzed consisted of 492 public elementary school children between kindergarten and fifth grade. Their ages ranged from 5 to 11 years. Trunk lift, 90° push-up, curl-up, and back saver sit and reach tests were administered. Weight status was determined using BMI scores and the CDC growth charts. Obesity prevalence remains high among elementary school-aged children in Corpus Christi, Texas. Higher 90° push-up test scores were most consistently associated with decreased odds of being obese as compared to being overweight and having healthy weight except in kindergarten. Conversely, higher trunk lift test scores were associated with increased odds of being obese in second and fourth grades. When children achieved the minimum score to be classified in the Healthy Fitness Zone, those with healthy weight had similarly low musculoskeletal fitness (i.e., abdominal strength and endurance, hamstring flexibility, and trunk extensor strength and flexibility as peers with overweight and obesity, especially in the lower grades. It was concluded that increased obesity prevalence in higher grades may be precipitated (at least in part by low musculoskeletal fitness in the lower grades, especially kindergarten. Given previous associations in the literature, low musculoskeletal fitness may be symptomatic of poor motor skill competence in the current sample. These findings suggest a need for early and focused school-based interventions that leverage both known and novel strategies to combat pediatric obesity in Corpus Christi.

  12. Delineation of marsh types from Corpus Christi Bay, Texas, to Perdido Bay, Alabama, in 2010

    Science.gov (United States)

    Enwright, Nicholas M.; Hartley, Stephen B.; Couvillion, Brady R.; Michael G. Brasher,; Jenneke M. Visser,; Michael K. Mitchell,; Bart M. Ballard,; Mark W. Parr,; Barry C. Wilson,

    2015-07-23

    Coastal zone managers and researchers often require detailed information regarding emergent marsh vegetation types (that is, fresh, intermediate, brackish, and saline) for modeling habitat capacities and needs of marsh dependent taxa (such as waterfowl and alligator). Detailed information on the extent and distribution of emergent marsh vegetation types throughout the northern Gulf of Mexico coast has been historically unavailable. In response, the U.S. Geological Survey, in collaboration with the Gulf Coast Joint Venture, the University of Louisiana at Lafayette, Ducks Unlimited, Inc., and the Texas A&M University-Kingsville, produced a classification of emergent marsh vegetation types from Corpus Christi Bay, Texas, to Perdido Bay, Alabama.

  13. La arquitectura del pleno barroco en Granada: el hospital del Corpus Christi

    Directory of Open Access Journals (Sweden)

    Barrios Rozúa, Juan Manuel

    2011-03-01

    Full Text Available The Corpus Christi hospital of Granada was a victim of prejudices against the baroque on the part of influential historians. Nevertheless, the building is an interesting example of hospital architecture with a frankly original temple. Thanks to the exhaustive analysis of the institution’s very complete archive, it can be determined that some thirty artists worked there, including Alonso Cano and his disciple Juan Luis de Ortega, whose architectural works are evaluated here.

    El hospital del Corpus Christi de Granada fue víctima de los prejuicios contra el barroco de influyentes historiadores. Sin embargo, el edificio constituye un interesante ejemplo de arquitectura hospitalaria con un templo francamente original. Gracias al análisis exhaustivo de su completo archivo, puede detectarse la labor de una treintena de artífices, entre ellos Alonso Cano y su discípulo Juan Luis de Ortega, cuyas obras arquitectónicas son valoradas aquí.

  14. Status, trends, and changes in freshwater inflows to bay systems in the Corpus Christi Bay National Estuary Program study area

    Science.gov (United States)

    Asquith, W.H.; Mosier, J. G.; Bush, P.W.

    1997-01-01

    This report presents the results of a study to quantify current (1983–93) mean freshwater inflows to the six bay systems (open water and wetlands) in the Corpus Christi Bay National Estuary Program study area, to test for historical temporal trends in inflows, and to quantify historical and projected changes in inflows. The report also addresses the adequacy of existing data to estimate freshwater inflows.

  15. Multibeam collection for FK005C: Multibeam data collected aboard Falkor from 2012-10-08 to 2012-10-20, Corpus Christi, TX to Corpus Christi, TX

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  16. Procedimiento de análisis para el estudio del proceso constructivo documentado del Colegio de Corpus Christi de Valencia

    Directory of Open Access Journals (Sweden)

    Lerma, C.

    2014-03-01

    Full Text Available The analysis procedure of the historic building construction sequence must establish the relationship between the documentation study that is conserved and its current state, noting the inconsistencies that occur. This paper focuses on the Seminary-School of Corpus Christi of Valencia, which is 400 years old and retains plenty of original documents relating to its construction. All aspects of the architecture and the construction of the building are analyzed in detail. A graphic study of the costs and three-dimensional hypothesis of the building construction sequence clarify how occurred its construction process. The proposed methodology can be used to study other construction processes in historical buildings.El procedimiento de análisis de la secuencia constructiva de un edificio histórico debe establecer la relación entre el estudio de la documentación que se conserva y el estado actual del mismo, advirtiendo las incongruencias que se produzcan. Este trabajo se centra en el Colegio-Seminario de Corpus Christi de Valencia, que cuenta con una antigüedad de 400 años y conserva abundante documentación original relativa a su construcción. Se analizan con detalle todos los aspectos relacionados con la arquitectura y la construcción del edificio, aclarando cómo se produjo el proceso de construcción, facilitando un estudio gráfico de los gastos y una hipótesis tridimensional de la secuencia constructiva. La metodología que se propone puede servir para el estudio de procesos constructivos en otros edificios históricos.

  17. ESTUDIO SOBRE DIFERENTES TIPOS DE PLANCHAS EN RELIEVE PARA LA REALIZACIÓN DE UNA SERIE. OBRAS SOBRE LA FIESTA DEL "CORPUS CHRISTI DE VALENCIA"

    OpenAIRE

    VIDAL MARTÍNEZ, MARÍA DOLORES

    2016-01-01

    [EN]b In this work, I have carried out a series of embossed engravements in order to study the behaviour of expressive effects in different types of matrices, within the framework of the Corpus Christi festivity in Valencia. This festival is extremely unique, as it combines different concepts, such as tradition, religion, legend, symbolism and popular culture, in a single celebration. This perfect combination of matrices enriches its artistics aspects in a simple manner, and the embossed engr...

  18. Ethnic Differences in Poststroke Quality of Life in the Brain Attack Surveillance in Corpus Christi (BASIC) Project.

    Science.gov (United States)

    Reeves, Sarah L; Brown, Devin L; Baek, Jonggyu; Wing, Jeffrey J; Morgenstern, Lewis B; Lisabeth, Lynda D

    2015-10-01

    Mexican Americans (MAs) have an increased risk of stroke and experience worse poststroke disability than non-Hispanic whites, which may translate into worse poststroke quality of life (QOL). We assessed ethnic differences in poststroke QOL, as well as potential modification of associations by age, sex, and initial stroke severity. Ischemic stroke survivors were identified through the biethnic, population-based Brain Attack Surveillance in Corpus Christi (BASIC) Project. Data were collected from medical records, baseline interviews, and 90-day poststroke interviews. Poststroke QOL was measured at ≈90 days by the validated short-form stroke-specific QOL in 3 domains: overall, physical, and psychosocial (range, 0-5; higher scores represent better QOL). Tobit regression was used to model associations between ethnicity and poststroke QOL scores, adjusted for demographics, clinical characteristics, and prestroke cognition and function. Among 290 eligible stroke survivors (66% MA, 34% non-Hispanic whites, median age=69 years), median scores for overall, physical, and psychosocial poststroke QOL were 3.3, 3.8, and 2.7, respectively. Poststroke QOL was lower for MAs than non-Hispanic whites both overall (mean difference, -0.30; 95% confidence interval, -0.59, -0.01) and in the physical domain (mean difference, -0.47; 95% confidence interval, -0.81, -0.14) after multivariable adjustment. No ethnic difference was found in the psychosocial domain. Age modified the associations between ethnicity and poststroke QOL such that differences were present in older but not in younger ages. Disparities exist in poststroke QOL for MAs and seem to be driven by differences in older stroke patients. Targeted interventions to improve outcomes among MA stroke survivors are urgently needed. © 2015 American Heart Association, Inc.

  19. Sources of suspended-sediment loads in the lower Nueces River watershed, downstream from Lake Corpus Christi to the Nueces Estuary, south Texas, 1958–2010

    Science.gov (United States)

    Ockerman, Darwin J.; Heitmuller, Franklin T.; Wehmeyer, Loren L.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the U.S. Army Corps of Engineers, Fort Worth District; City of Corpus Christi; Guadalupe-Blanco River Authority; San Antonio River Authority; and San Antonio Water System, developed, calibrated, and tested a Hydrological Simulation Program-FORTRAN (HSPF) watershed model to simulate streamflow and suspended-sediment concentrations and loads during 1958-2010 in the lower Nueces River watershed, downstream from Lake Corpus Christi to the Nueces Estuary in south Texas. Data available to simulate suspended-sediment concentrations and loads consisted of historical sediment data collected during 1942-82 in the study area and suspended-sediment concentration data collected periodically by the USGS during 2006-7 and 2010 at three USGS streamflow-gaging stations (08211000 Nueces River near Mathis, Tex. [the Mathis gage], 08211200 Nueces River at Bluntzer, Tex. [the Bluntzer gage], and 08211500 Nueces River at Calallen, Tex. [the Calallen gage]), and at one ungaged location on a Nueces River tributary (USGS station 08211050 Bayou Creek at Farm Road 666 near Mathis, Tex.). The Mathis gage is downstream from Wesley E. Seale Dam, which was completed in 1958 to impound Lake Corpus Christi. Suspended-sediment data collected before and after completion of Wesley E. Seale Dam provide insights to the effects of the dam and reservoir on suspended-sediment loads transported by the lower Nueces River downstream from the dam to the Nueces Estuary. Annual suspended-sediment loads at the Nueces River near the Mathis, Tex., gage were considerably lower for a given annual mean discharge after the dam was completed than before the dam was completed.

  20. corpus_christi.grd

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NGDC builds and distributes high-resolution, coastal digital elevation models (DEMs) that integrate ocean bathymetry and land topography to support NOAA's mission to...

  1. Delineation of marsh types of the Texas coast from Corpus Christi Bay to the Sabine River in 2010

    Science.gov (United States)

    Enwright, Nicholas M.; Hartley, Stephen B.; Brasher, Michael G.; Visser, Jenneke M.; Mitchell, Michael K.; Ballard, Bart M.; Parr, Mark W.; Couvillion, Brady R.; Wilson, Barry C.

    2014-01-01

    Coastal zone managers and researchers often require detailed information regarding emergent marsh vegetation types for modeling habitat capacities and needs of marsh-reliant wildlife (such as waterfowl and alligator). Detailed information on the extent and distribution of marsh vegetation zones throughout the Texas coast has been historically unavailable. In response, the U.S. Geological Survey, in cooperation and collaboration with the U.S. Fish and Wildlife Service via the Gulf Coast Joint Venture, Texas A&M University-Kingsville, the University of Louisiana-Lafayette, and Ducks Unlimited, Inc., has produced a classification of marsh vegetation types along the middle and upper Texas coast from Corpus Christi Bay to the Sabine River. This study incorporates approximately 1,000 ground reference locations collected via helicopter surveys in coastal marsh areas and about 2,000 supplemental locations from fresh marsh, water, and “other” (that is, nonmarsh) areas. About two-thirds of these data were used for training, and about one-third were used for assessing accuracy. Decision-tree analyses using Rulequest See5 were used to classify emergent marsh vegetation types by using these data, multitemporal satellite-based multispectral imagery from 2009 to 2011, a bare-earth digital elevation model (DEM) based on airborne light detection and ranging (lidar), alternative contemporary land cover classifications, and other spatially explicit variables believed to be important for delineating the extent and distribution of marsh vegetation communities. Image objects were generated from segmentation of high-resolution airborne imagery acquired in 2010 and were used to refine the classification. The classification is dated 2010 because the year is both the midpoint of the multitemporal satellite-based imagery (2009–11) classified and the date of the high-resolution airborne imagery that was used to develop image objects. Overall accuracy corrected for bias (accuracy

  2. «En los mayores peligros se conoce la amistad» («Friendship is Best Acknowledged when in Danger», an Auto Sacramental (Eucharistic Morality Play by José de Valdivieso, Staged at the Corpus Christi Feast in Seville, in 1619. An Analysis and a Virtual Reconstruction

    Directory of Open Access Journals (Sweden)

    Mercedes de los Reyes Peña

    2017-11-01

    Full Text Available This paper studies José de Valdivieso’s En los mayores peligros se conoce la amistad (Friendship is best acknowledged when in danger one of the five autos sacramentales (Eucharistic morality plays staged at the Corpus Christi feast in Seville, in 1619, by Diego de Vallejo. It also bears the title La amistad en el peligro (Friendship when in danger, and has never been published in a modern critical edition, though two published records (1622 and 1624 bear witness to the play, of which there are two 17 th Century manuscript versions extant. This article, based on contemporary records, studies the historical socio-religious- urban context of the Corpus Christi feast in Seville and virtually reconstructs the play’s performance, on pageant wagons, and its subsequent procession within the town.

  3. 76 FR 68188 - Valero Refining-Texas, L.P. v. Port of Corpus Christi Authority of Nueces County, TX; Notice of...

    Science.gov (United States)

    2011-11-03

    ..., Texas (PCCA) hereinafter ``Respondent''. Complainant asserts that it is a limited partnership duly... or unreasonable prejudice or disadvantage; (b) granting an undue preference or advantage with respect...

  4. Corpus ChristiEast Matagorda Bay 1986

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Patterns of habitat utilization were compared among transplanted and natural Spartina alterniflora marshes in the Halls Lake area of Chocolate Bay in the Galveston...

  5. Corpus Christi, Texas Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  6. Corpus Christi EFH Trawling Effects 2001-2002

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — We compared sediments and benthos of two adjacent zones of the middle Texas coast, one of which was closed to shrimp trawling for 7 months. Findings indicated that...

  7. Christie's politseiga pahuksis / Maria-Kristiina Soomre

    Index Scriptorium Estoniae

    Soomre, Maria-Kristiina, 1978-

    2001-01-01

    9. II Londonis toimuv Christie'si kunstioksjon on saanud politsei teravdatud tähelepanu osaliseks kolme Andres Serrano foto pärast seeriast "History of Sex" (1996). On võimalik teoste müügilt kõrvaldamine.

  8. Old Persian corpus [Dataset

    NARCIS (Netherlands)

    Bavant, M.

    2011-01-01

    XML Old Persian corpus. The corpus is based on publicly available data on the Web. Those data can be traced back to the grammar of Old Persian by Kent (1950). The corpus contains those data and is arranged in a way suitable for corpus searches.

  9. Hirst kukkus Christie'sis läbi

    Index Scriptorium Estoniae

    1998-01-01

    Christie'si kunstioksjon 8. ja 9. X Londonis. Isiklike müügirekorditeni tõusid Felix Gonzalez-Torrese, Jeff Walli ja Anish Kapoori tööde hinnad. Damien Hirst müüs ühe maali. Ostjat ei leidnud Gerhard Richteri maal 'Seestück', oksjoni kalleim töö

  10. Philosophy and Religion in service of the Philosophia Christi

    NARCIS (Netherlands)

    N. Linkels (Nicole)

    2013-01-01

    textabstractDesiderius Erasmus proposed a philosophia Christi, in which – at least to the Renaissance humanist – both religion and philosophy dictate the Christian way of living. The very term implies that philosophy and religion share a common ground. It fails, however, to acknowledge the

  11. Coastal Bend Texas Benthic Habitat Mapping Corpus Christi Bay 2004 Geoform

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2006 and 2007 the NOAA Office for Coastal Management purchased services to process existing digital multi-spectral imagery (ADS-40) and create digital benthic...

  12. 2012 NOAA Color Ortho-rectified Mosaic of Corpus Christi to Saint Charles Bay, Texas

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains ortho-rectified mosaic tiles, created as a product from the NOAA Integrated Ocean and Coastal Mapping (IOCM) initiative. The source imagery...

  13. H10360: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1991-02-27

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  14. H10327: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1990-10-26

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  15. H10328: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1990-04-09

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  16. H10361: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1991-01-16

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  17. H10323: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1990-01-26

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  18. H10326: NOS Hydrographic Survey , Corpus Christi and Aransas Bays, Texas, 1990-11-01

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Oceanic and Atmospheric Administration (NOAA) has the statutory mandate to collect hydrographic data in support of nautical chart compilation for safe...

  19. All Roads Lead to Property: Pashukains, Christie and the Theory of ...

    African Journals Online (AJOL)

    Nils Christie is acknowledged generally as the theoretical founding father of restorative justice. Evgeny Pashukanis may be taken as the premier Marxist theoretician of law. This essay represents an endeavour to read Christie through the lens of Pashukanism, that is, to comprehend the theory of restorative justice developed ...

  20. In vitro shoot multiplication of Ziziphus spina-christi by shoot tip culture

    African Journals Online (AJOL)

    USER

    2010-02-08

    Feb 8, 2010 ... Key words: Clonal propagation, cidir, shoot tip culture, Ziziphus spina-christi (L.) Desf. INTRODUCTION. Ziziphus spina-christi (L.) Desf., locally known as cidir, is a multipurpose tree species belonging to the botanical family Rhamnaceae. It is an important cultivated tree and one of the few truly native tree ...

  1. Data modelling in corpus linguistics: how low may we go?

    Science.gov (United States)

    van Velzen, Marjolein H; Nanetti, Luca; de Deyn, Peter P

    2014-06-01

    Corpus linguistics allows researchers to process millions of words. However, the more words we analyse, i.e., the more data we acquire, the more urgent the call for correct data interpretation becomes. In recent years, a number of studies saw the light attempting to profile some prolific authors' linguistic decline, linking this decline to pathological conditions such as Alzheimer's Disease (AD). However, in line with the nature of the (literary) work that was analysed, numbers alone do not suffice to 'tell the story'. The one and only objective of using statistical methods for the analysis of research data is to tell a story--what happened, when, and how. In the present study we describe a computerised but individualised approach to linguistic analysis--we propose a unifying approach, with firm grounds in Information Theory, that, independently from the specific parameter being investigated, guarantees to produce a robust model of the temporal dynamics of an author's linguistic richness over his or her lifetime. We applied this methodology to six renowned authors with an active writing life of four decades or more: Iris Murdoch, Gerard Reve, Hugo Claus, Agatha Christie, P.D. James, and Harry Mulisch. The first three were diagnosed with probable Alzheimer Disease, confirmed post-mortem for Iris Murdoch; this same condition was hypothesized for Agatha Christie. Our analysis reveals different evolutive patterns of lexical richness, in turn plausibly correlated with the authors' different conditions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Experimental model of human corpus cavernosum smooth muscle relaxation

    Directory of Open Access Journals (Sweden)

    Rommel P. Regadas

    2010-08-01

    Full Text Available PURPOSE: To describe a technique for en bloc harvesting of the corpus cavernosum, cavernous artery and urethra from transplant organ donors and contraction-relaxation experiments with corpus cavernosum smooth muscle. MATERIALS AND METHODS: The corpus cavernosum was dissected to the point of attachment with the crus penis. A 3 cm segment (corpus cavernosum and urethra was isolated and placed in ice-cold sterile transportation buffer. Under magnification, the cavernous artery was dissected. Thus, 2 cm fragments of cavernous artery and corpus cavernosum were obtained. Strips measuring 3 x 3 x 8 mm3 were then mounted vertically in an isolated organ bath device. Contractions were measured isometrically with a Narco-Biosystems force displacement transducer (model F-60, Narco-Biosystems, Houston, TX, USA and recorded on a 4-channel Narco-Biosystems desk model polygraph. RESULTS: Phenylephrine (1µM was used to induce tonic contractions in the corpus cavernosum (3 - 5 g tension and cavernous artery (0.5 - 1g tension until reaching a plateau. After precontraction, smooth muscle relaxants were used to produce relaxation-response curves (10-12M to 10-4 M. Sodium nitroprusside was used as a relaxation control. CONCLUSION: The harvesting technique and the smooth muscle contraction-relaxation model described in this study were shown to be useful instruments in the search for new drugs for the treatment of human erectile dysfunction.

  3. Greening America's Capitals - Austin, TX

    Science.gov (United States)

    Report on the technical assistance project to help Austin, TX, develop a vision for the South Central Waterfront that incorporates green infrastructure to manage stormwater runoff, makes streets safer, and spurs investment.

  4. Ei saa me läbi Rootsita ja Christie meelest ei kao : Raamaturida / Arno Oja

    Index Scriptorium Estoniae

    Oja, Arno, 1950-

    1995-01-01

    Görling, Lars. 491; Bergman, Hjalmar. Juhataja proua Ingeborg; Lindberg, Margareta. Paradiisi Oskar; Bönnen, Rolf. Flirtida - aga kuidas?;Christie, Agatha. Kaardid lauale. Chimneysi saladus; Forsyth, Frederick. Odessa toimik

  5. Language Planning: Corpus Planning.

    Science.gov (United States)

    Baldauf, Richard B., Jr.

    1989-01-01

    Focuses on the historical and sociolinguistic studies that illuminate corpus planning processes. These processes are broken down and discussed under two categories: those related to the establishment of norms, referred to as codification, and those related to the extension of the linguistic functions of language, referred to as elaboration. (60…

  6. CREATING AND PROCESSING A CORPUS

    Directory of Open Access Journals (Sweden)

    Prihantoro

    2015-05-01

    Full Text Available This paper seeks to describe some crucial importance of corpus and text processing. Corpus is a projection of how language is used by its speakers. Technology support has improved corpus for easier maintenance, made it space-saving, and it may electronically structure its data. The latest offers much freedom for corpus users to access and exploit it for language teaching, analysis or other specified tasks. This paper will demonstrate how to use open-access corpus on internet such as Corpus of Contemporary American English (COCA and British National Corpus (BNC. Besides how to use a corpus, another crucial importance that this paper seeks to describe is how to build a corpus. In this paper, the writer will use UNITEX, a corpus (text-based processing software. This software will demonstrate steps of corpus building, ranging from text collection, annotation, electronic dictionary application to some natural language based operations ranging from pattern matching, concordance, to simple extraction. It will show how graph technology may outperform regular expression, a retrieval method exploited by other corpus processor, in terms of writing output.

  7. Seasonal Change in Nearshore and Channel Morphology at Packery Channel, A New Inlet Serving Corpus Christi, Texas

    Science.gov (United States)

    2011-01-01

    position defined by limiting features such as the dune toe or seawall. Individual transects are spaced at 1 to 30 m apart. These surveys usually require...associated nominal depths (MSL) are: 1) a wading survey conducted from the landward limiting feature, such as dune or seawall, to offshore depth of...Hall Pier. The surge forced water up to the dune line adjacent to the channel. The water was funneled toward and into the inlet, introducing sand from

  8. Web corpus construction

    CERN Document Server

    Schafer, Roland

    2013-01-01

    The World Wide Web constitutes the largest existing source of texts written in a great variety of languages. A feasible and sound way of exploiting this data for linguistic research is to compile a static corpus for a given language. There are several adavantages of this approach: (i) Working with such corpora obviates the problems encountered when using Internet search engines in quantitative linguistic research (such as non-transparent ranking algorithms). (ii) Creating a corpus from web data is virtually free. (iii) The size of corpora compiled from the WWW may exceed by several orders of magnitudes the size of language resources offered elsewhere. (iv) The data is locally available to the user, and it can be linguistically post-processed and queried with the tools preferred by her/him. This book addresses the main practical tasks in the creation of web corpora up to giga-token size. Among these tasks are the sampling process (i.e., web crawling) and the usual cleanups including boilerplate removal and rem...

  9. Towards an integrated corpus stylistics

    Directory of Open Access Journals (Sweden)

    McIntyre Dan

    2015-12-01

    Full Text Available Over recent years, the use of corpora in stylistic analysis has grown in popularity. However, questions still remain over the remit of corpus stylistics, its distinction from corpus linguistics generally and its capacity to explain complex stylistic effects. This article argues in favour of an integrated corpus stylistics; that is, an approach to corpus stylistics that integrates it with other stylistic methods and analytical frameworks. I suggest that this approach is needed for two main reasons: (i it is analytically necessary in order to fully explain stylistic effects in texts, and (ii integrating corpus methods with other stylistic tools is what will distinguish corpus stylistics from corpus linguistics. My argument is supported by reference to examples from Mark Haddon’s no vel The Curious Incident of the Dog in the Night-time and the HBO TV series Deadwood. Both these examples rely for their explanation on a combination of corpus stylistic analytical techniques and other stylistic methods of analysis.

  10. Corpus Approaches to Language Ideology

    Science.gov (United States)

    Vessey, Rachelle

    2017-01-01

    This paper outlines how corpus linguistics--and more specifically the corpus-assisted discourse studies approach--can add useful dimensions to studies of language ideology. First, it is argued that the identification of words of high, low, and statistically significant frequency can help in the identification and exploration of language ideologies…

  11. Corpus vitreum, retina og chorioidea biopsi

    DEFF Research Database (Denmark)

    Scherfig, Erik Christian Høegh

    2002-01-01

    oftalmology, biopsy, choroid, corpus vitreum, retina, malignant melanoma, biopsy technic, retinoblastoma......oftalmology, biopsy, choroid, corpus vitreum, retina, malignant melanoma, biopsy technic, retinoblastoma...

  12. "60x30TX" 2017 Progress Report

    Science.gov (United States)

    Texas Higher Education Coordinating Board, 2017

    2017-01-01

    Central to the goals of "60x30TX" is maintaining Texas as a global economic player by having an educated population, making them aware of their marketable skills, and helping them manage their student loan debt. If the 2016 progress report for "60x30TX" was about getting out the word, this report is about expanding that reach…

  13. Photometric Orbit of TX UMa

    Directory of Open Access Journals (Sweden)

    Kyu-Dong Oh

    1986-06-01

    Full Text Available Two-color photometric light curves (Oh and Chan 1984 of the eclipsing binary TX UMa have been analyzed by the method of differential corrections of the model of Wilson and Devinney(1971. The system found to be simi-detached with cooler and less massive component filling its Roche lobe. The absolute dimensions have been derived from the results of the photometric solutions with spectroscopic elements of Hiltner(1945. It is assumed that the B8V primary component is on the zero age main sequence stage of the core hydrogen burning and the secondary os at the core contraction stage after the shell hydrogen burning stage according to the Iben's (1967 evolutional tracks for 3.0m_solar and 1.0m_solar.

  14. 78 FR 34349 - Schedules for Atlantic Shark Identification Workshops and Protected Species Safe Handling...

    Science.gov (United States)

    2013-06-07

    ...; Kenner, LA; Charleston, SC; and Corpus Christi, TX. See SUPPLEMENTARY INFORMATION for further details on... Inn & Suites, 3312 Vista Drive, Rosenberg, TX 77471. 3. September 12, 2013, 12 p.m.-4 p.m., Holiday..., Kenner, LA 70062. 5. September 10, 2013, 9 a.m.-5 p.m., Holiday Inn, 301 Savannah Highway, Charleston, SC...

  15. Shoaling Analysis at Brazos Island, Harbor Inlet, Texas

    Science.gov (United States)

    2015-10-01

    and, consequently, is not a high priority for maintenance dredging funding. However, any impacts to inbound vessels ensure a major negative economic...Brownsville Ship Channel. Corpus Christi, TX. Report prepared for Port of Brownsville, TX. Martin Associates. 2008. Market assessment of the Port of

  16. Orfismo en el Corpus Philostrateum

    Directory of Open Access Journals (Sweden)

    Susana M. Lizcano Rejano

    2003-06-01

    Full Text Available We search through the Corpus Philostrateum for the presence of connections between this literary production and Orphismus – its system of beliefs, its peculiar interpretation of the traditional Greek mythology, its proposal for a particular way of life. Also, we try to determine the relation, that we can find in this corpus between the ideology and customs that the Pythagoreans and Orphics supported.

  17. Commentary on "Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation." Kapur P, Peña-Llopis S, Christie A, Zhrebker L, Pavía-Jiménez A, Rathmell WK, Xie XJ, Brugarolas J. Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX. Lancet Oncol 2013; 14(2):159-67. [Epub 2013 Jan 16]. doi: 10.1016/S1470-2045(12)70584-3.

    Science.gov (United States)

    Boorjian, Stephen

    2014-08-01

    Clear-cell renal-cell carcinomas display divergent clinical behaviours. However, the molecular genetic events driving these behaviours are unknown. We discovered that BAP1 is mutated in about 15% of clear-cell renal-cell carcinoma, and that BAP1 and PBRM1 mutations are largely mutually exclusive. The aim of this study was to investigate the clinicopathological significance of these molecular subtypes and to determine whether patients with BAP1-mutant and PBRM1-mutant tumours had different overall survival. In this retrospective analysis, we assessed 145 patients with primary clear-cell renal-cell carcinoma and defined PBRM1 and BAP1 mutation status from the University of Texas Southwestern Medical Center (UTSW), TX, USA, between 1998 and 2011. We classified patients into those with BAP1-mutant tumours and those with tumours exclusively mutated for PBRM1 (PBRM1-mutant). We used a second independent cohort (n=327) from The Cancer Genome Atlas (TCGA) for validation. In both cohorts, more than 80% of patients had localised or locoregional disease at presentation. Overall both cohorts were similar, although the TCGA had more patients with metastatic and higher-grade disease, and more TCGA patients presented before molecularly targeted therapies became available. The median overall survival in the UTSW cohort was significantly shorter for patients with BAP1-mutant tumours (4·6 years; 95% CI 2·1-7·2), than for patients with PBRM1-mutant tumours (10·6 years; 9·8-11·5), corresponding to a HR of 2·7 (95% CI 0·99-7·6, p=0·044). Median overall survival in the TCGA cohort was 1·9 years (95% CI 0·6-3·3) for patients with BAP1-mutant tumours and 5·4 years (4·0-6·8) for those with PBRM1-mutant tumours. A HR similar to the UTSW cohort was noted in the TCGA cohort (2·8; 95% CI 1·4-5·9; p=0·004). Patients with mutations in both BAP1 and PBRM1, although a minority (three in UTSW cohort and four in TCGA cohort), had the worst overall survival (median 2·1 years, 95

  18. Quantitative modeling of flavonoid glycosides isolated from Paliurus spina-christi Mill.

    OpenAIRE

    Medić-Šarić, Marica; Maleš, Željan; Šarić, Slavko; Brantner, Adelheid

    1996-01-01

    Several QSPR models for predicting the properties of flavonoid glycosides isolated from Paliurus spina-christi Mill, and of some related flavonoids were described and evaluated. Log P values for all of them were calculated according to the method of Rekker. All investigated flavonoids showed expressive hydrophobicity. Significant correlation between the partition coefficient, log P, and van der Waals volume, Vw (calculated according to the method described by Moriguchi et al.) was obtained. T...

  19. Optical photometry of TX0506+056

    Science.gov (United States)

    Keel, William; Santander, Marcos

    2017-10-01

    The blazar TX0506+056 has attracted recent attention through its location in the error box of a high-energy Ice Cube neutrino detection (https://gcn.gsfc.nasa.gov/gcn3/21916.gcn3) and gamma-ray flaring (Atel #10791) We report recent photometry of TX0506+056 obtained in Johnson V and Cousins R passbands using the 1-meter Kapteyn telescope at La Palma, operated remotely by the SARA consortium.

  20. 77 FR 19521 - Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund Federal...

    Science.gov (United States)

    2012-04-02

    ... Austin, TX and Waco, TX, Appropriated Fund Federal Wage System Wage Areas AGENCY: U.S. Office of... final rule to redefine the geographic boundaries of the Austin, TX, and Waco, TX, appropriated fund... the Austin wage area to the Waco wage area. These changes are based on recent consensus...

  1. A Balanced and Representative Corpus: The Effects of Strict Corpus ...

    African Journals Online (AJOL)

    Theoretically the Northern Sotho language is made up of almost 30 dialects while practically it is not so, because the standard language was formed from very few of its dialects. As a result, even today the language has no corpus which is balanced or representative owing to the fact that almost all of the available corpora ...

  2. Lancaster Summer School in Corpus Linguistics

    Directory of Open Access Journals (Sweden)

    Jaka Čibej

    2016-11-01

    Full Text Available Med 12. in 15. julijem je na Univerzi v Lancastru potekala poletna šola korpusnega jezikoslovja Lancaster Summer Schools in Corpus Linguistics and Other Digital Methods. Poletno šolo so organizirali UCREL (University Centre for Computer Corpus Research on Language, ERC (Evropski svet za raziskave – European Research Council, CASS (ESRC Centre for Corpus Approaches to Social Science in ESRC (Economic and Social Research Council, razdeljena pa je bila na šest programov, prilagojenih različnim področjem: Korpusno jezikoslovje za proučevanje jezikov (Corpus Linguistics for Language Studies, Korpusno jezikoslovje za družbene vede (Corpus Linguistics for Social Science, Korpusno jezikoslovje za humanistiko (Corpus Linguistics for Humanities, Statistika za korpusno jezikoslovje (Statistics for Corpus Linguistics, Geografski informacijski sistemi za digitalno humanistiko (Geographical Information Systems for the Digital Humanities in Korpusno podprta obdelava naravnih jezikov (Corpus-based Natural Language Processing.

  3. The Corpus of Czech Verse

    Czech Academy of Sciences Publication Activity Database

    Plecháč, Petr; Kolár, Robert

    2015-01-01

    Roč. 2, č. 1 (2015), s. 107-118 ISSN 2346-6901 R&D Projects: GA ČR GAP406/11/1825 Institutional support: RVO:68378068 Keywords : Czech poetry * versification * corpus linguistics * theory of verse Subject RIV: AJ - Letters, Mass-media, Audiovision

  4. Agenesis of the Corpus Callosum

    Science.gov (United States)

    ... callosum, the structure that connects the two hemispheres (left and right) of the brain. In ACC the corpus callosum is partially or completely absent. It is caused by a disruption of brain cell migration during fetal development. ACC can occur as an isolated condition or ...

  5. Towards proper name generation : A corpus analysis

    NARCIS (Netherlands)

    Castro Ferreira, Thiago; Wubben, Sander; Krahmer, Emiel

    We introduce a corpus for the study of proper name generation. The corpus consists of proper name references to people in webpages, extracted from the Wikilinks corpus. In our analyses, we aim to identify the different ways, in terms of length and form, in which a proper names are produced

  6. TxDOT administration research : tasks completed in FY2009.

    Science.gov (United States)

    2010-01-01

    Texas Department of Transportation (TxDOT) Project 0-6581-TI, TxDOT Administration : Research, encompasses multiple tasks that explore and support administrative aspects of : transportation research. : The project term began in October 2008 and has b...

  7. Tank 241-TX-118 tank characterization plan

    International Nuclear Information System (INIS)

    Carpenter, B.C.

    1994-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-118

  8. Tank 241-TX-105 tank characterization plan

    International Nuclear Information System (INIS)

    Carpenter, B.C.

    1995-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-105

  9. 75 FR 31677 - Amendment of Class E Airspace; Austin, TX

    Science.gov (United States)

    2010-06-04

    ...-1152; Airspace Docket No. 09-ASW-31] Amendment of Class E Airspace; Austin, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for the Austin, TX... Procedures (SIAPs) at Austin Executive Airport, Austin, TX. The FAA is taking this action to enhance the...

  10. 76 FR 52563 - Special Local Regulations; Sabine River, Orange, TX

    Science.gov (United States)

    2011-08-23

    ...-AA08 Special Local Regulations; Sabine River, Orange, TX AGENCY: Coast Guard, DHS. ACTION: Temporary... Regulations; Sabine River, Orange, TX in the Federal Register (76 FR 103). We received no comments on the... Regulations for Marine Events; Sabine River, Orange, TX. (a) Definitions. As used in this section...

  11. Spotlight on solithromycin in the treatment of community-acquired bacterial pneumonia: design, development, and potential place in therapy

    Directory of Open Access Journals (Sweden)

    Donald BJ

    2017-12-01

    Full Text Available Bryan J Donald,1,2 Salim Surani,3–5 Harmeet S Deol,1,6 Uche J Mbadugha,1 George Udeani1,7 1Department of Pharmacy, Corpus Christi Medical Center, Corpus Christi, TX, 2Department of Clinical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe, LA, 3Department of Pulmonology/Critical Care, Corpus Christi Medical Center, Corpus Christi, TX, 4Department of Medicine, College of Medicine, Texas A&M University Health Science Center, College Station, TX, 5Department of Medicine, College of Osteopathic Medicine, University of North Texas Health Science Center, Denton, TX, 6Department of Pharmacy Services, Yale New Haven Hospital, New Haven, CT, 7Pharmacy Practice, College of Pharmacy, Texas A&M University Health Science Center, Kingsville, TX, USA Abstract: Community-acquired bacterial pneumonia (CABP is a leading cause of death worldwide. However, antibacterial agents used to treat common pathogens in CABP are marked by adverse drug events and increasing antimicrobial resistance. Solithromycin is a new ketolide antibiotic, based on the macrolide antibiotic structure, being studied for use in CABP. It has efficacy in vitro against the common causative pathogens in CABP including Streptococcus pneumoniae, Haemophilus influenzae, and atypical pathogens. In Phase II and Phase III clinical trials, it has been demonstrated efficacious as a single agent for treatment of CABP with an apparently milder adverse event profile than alternative agents. Keywords: solithromycin, macrolide antibiotics, community-acquired bacterial pneumonia, CABP

  12. CORPUS

    DEFF Research Database (Denmark)

    Scholl, Gerd; Berger, Gerald; Freytag, Elisabeth

    2016-01-01

    experience with a knowledge brokerage system comprised of two intertwined building blocks, a series of “policy meets research” workshops which attracted almost 300 professionals from all over Europe, and a web platform named “SCP Knowledge Hub” which evolved into a major knowledge repository for almost 900...... registered users. We identify three design principles for effective knowledge brokerage and overcoming of the translation barriers between science and policy - i.e. participatory, activating and modular - and formulate practical recommendations for brokering knowledge through an online medium....

  13. 76 FR 36613 - Environmental Impact Statement; Nueces County, TX

    Science.gov (United States)

    2011-06-22

    ... will be developed in compliance with Section 6002 of the Safe, Accountable, Flexible, Efficient... Organization's Metropolitan Transportation Plan 2010-2035 (the long range transportation plan) as construction... Christi. The impacts and benefits of such will also be analyzed in the indirect and cumulative impacts...

  14. Cerium intermetallics CeTX. Review III

    Energy Technology Data Exchange (ETDEWEB)

    Poettgen, Rainer; Janka, Oliver [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Chevalier, Bernard [Bordeaux Univ., Pessac (France). Inst. de Chimie de la Matiere Condensee de Bordeaux

    2016-05-01

    The structure-property relationships of CeTX intermetallics with structures other than the ZrNiAl and TiNiSi type are systematically reviewed. These CeTX phases form with electron-poor and electron-rich transition metals (T) and X = Mg, Zn, Cd, Hg, Al, Ga, In, Tl, Si, Ge, Sn, Pb, P, As, Sb, and Bi. The review focusses on the crystal chemistry, the chemical bonding peculiarities, and the magnetic and transport properties. Furthermore {sup 119}Sn Moessbauer spectroscopic data, high-pressure studies, hydrogenation reactions and the formation of solid solutions are reviewed. This paper is the third of a series of four reviews on equiatomic intermetallic cerium compound [Part I: R. Poettgen, B. Chevalier, Z. Naturforsch. 2015, 70b, 289; Part II: R. Poettgen, B. Chevalier, Z. Naturforsch. 2015, 70b, 695].

  15. Edition des Corpus areopagiticum slavicum

    Directory of Open Access Journals (Sweden)

    Dieter Fahl

    2005-12-01

    Full Text Available An Edition of the Corpus areopagiticum slavicum In the fourteenth century, the monk Isaiah of the holy Mount Athos translated the writings of pseudo-Dionysius the Areopagite (c. end of the 5th century, core texts for Eastern and Western European theological and philosophical thought, from Greek into Church Slavonic. This first Slavic translation of Dionysius’ oeuvre (“De Coelesti Hierarchia,” “De Ecclesiastica Hierarchia,” “De Divinis Nominibus,” “De Mystica Theologia,” the epistles and scholia, which played a significant role in the development of Slavic culture, Orthodox Slavic socio-political theory and praxis, is still central to the study of Slavia Orthodoxa. A working group of German and Russian scholars has completed an edition of the translator’s Church Slavonic autograph with an en face reconstruction of the Greek text used by the translator and philological commentary. A Church Slavonic-Greek and Greek-Church Slavonic dictionary of this edition, currently in preparation, plans to make the terminology used in this influential translation accessible to interdisciplinary researchers. For the first time, the Church Slavonic lexica of this corpus, a substantial part of which was coined by the translator, will be registered in an index of words and forms.

  16. Macropropagation and micropropagation of Ziziphus spina-christi Macropropagação e micropropagação de Ziziphus spina-christi

    Directory of Open Access Journals (Sweden)

    Mohammad Hassan Assareh

    2005-05-01

    Full Text Available Christ's thorn (Ziziphus spina-christi (L. Desf. is a cross-pollinated plant with a wide range of genetic variability in nature and, for this reason, vegetative propagation assumes importance for improvement programs. The objective of this work was to evaluate cutting, T budding and tissue culture methods for this species. Shoots of 22-25 cm length were treated by two culture media and three shoot diameters for cutting trial. The T budding treatments consisted of three and five collection dates in spring and autumn, respectively. Tissue culture nodal segments bearing axillary buds were removed from shoots of mature trees at different seasons. Experiments to determine the best disinfectant chemical, appropriate conditions and materials to prevent phenolic compound exudation, explant characteristics, media type and cytokinin-auxin ratios were carried out. Successful rooting happened only on the sand beds and with cuttings greater than 8 mm diameter. The effects of T budding seasons on budtake percentage were significantly different. The best time for explant harvesting was mid of summer. Amount of rooting on media containing IBA as well as activated charcoal and disinfection with Ca(OCl2 at concentration of 5% for 20 minutes were the best treatments.Ziziphus spina-christi (L. Desf. é uma planta de polinização cruzada com grande variabilidade genética na natureza e, por isso, sua propagação vegetativa assume importância para o melhoramento genético. O objetivo deste trabalho foi avaliar os métodos de estaquia, borbulhia em T e cultura de tecido na propagação vegetativa desta espécie. No ensaio de estaquia, partes aéreas da planta com 22-25 cm foram cultivadas em dois meios de cultura e com três diâmetros. O ensaio de borbulhia consistiu na coleta do material em três datas na primavera e em cinco datas no outono. Os segmentos nodais contendo gemas axilares foram removidos da parte aérea de árvores maduras, em diferentes esta

  17. Network Analysis with the Enron Email Corpus

    Science.gov (United States)

    Hardin, J. S.; Sarkis, G.; URC, P. .

    2015-01-01

    We use the Enron email corpus to study relationships in a network by applying six different measures of centrality. Our results came out of an in-semester undergraduate research seminar. The Enron corpus is well suited to statistical analyses at all levels of undergraduate education. Through this article's focus on centrality, students can explore…

  18. Corpus-Based Investigations of Language Use.

    Science.gov (United States)

    Biber, Douglas; And Others

    1996-01-01

    Examines a representative text corpus to gain insights into language structure and use and to open new areas of linguistic inquiry. Various illustrations are presented that provide a glimpse into the value of corpus-based investigations for increasing one's understanding of language use and imparting insights important for designing effective…

  19. Changes Are Needed to the Army Contract with Sikorsky to Use Existing DoD Inventory and Control Costs at the Corpus Christi Army Depot

    Science.gov (United States)

    2011-11-03

    contingency stock for requirements outside the CCAD/Sikorsky contract. 6 The DoD EMALL is a full-service eCommerce site, which strives to be the single...such quantity as (A) will result in the total cost and unit cost most advantageous to the United States where practicable.” Having more than one...practice and frequently does not allow DoD to take advantage of economic order quantities. Table 15 shows examples where higher quantities procured

  20. Simulated effects of projected pumping on the availability of freshwater in the Evangeline Aquifer in an area southwest of Corpus Christi, Texas

    Science.gov (United States)

    Groschen, George E.

    1985-01-01

    This study is an investigation of the continued availability of freshwater in the Evangeline aquifer along the Texas Gulf Coast and the potential for degradation of the water quality by salinewater intrusion. Recharge to the aquifer occurs by the infiltration of precipitation in the outcrop area and by cross-formational flow from deeper aquifers. The predevelopment recharge rate is about 6 to 8 cubic feet per second. The predevelopment flow is toward the coast. The flow is semiconfined in the outcrop area and confined underneath the Chicot aquifer in the eastern two-thirds of the study area. Discharge, under natural conditions, is upward into the Chicot aquifer and to the Nueces River or Gulf of Mexico. Intensive pumping by irrigators, industries, and municipalities over the last 80 years has created a cone of depression as deep as 219 feet below sea level under the city of Kingsville in Kleberg County. The total rate of pumpage in 1982 was 29.6 cubic feet per second.

  1. Verde plant bug (Hemiptera: Miridae) feeding injury to cotton bolls charcterized by boll age, size and damage ratings

    Science.gov (United States)

    Our studies over 2 years (2009 and 2010) and 2 locations (Weslaco and Corpus Christi, TX) investigated the relationship of feeding-injury of the verde plant bug, Creontiades signatus Distant, to a range of cotton boll age classes further defined by boll diameter and accumulated degree-days (anthesis...

  2. 78 FR 42755 - Gulf of Mexico Fishery Management Council; Public Hearings

    Science.gov (United States)

    2013-07-17

    ...: The Gulf of Mexico Fishery Management Council (Council) will hold public hearings for Coastal... through Friday August 15, 2013 at ten locations throughout the Gulf of Mexico. The public hearings will...; Mobile, AL; Corpus Christi and Texas City, TX. Council address: Gulf of Mexico Fishery Management Council...

  3. Christ's thorn formation (Paliureta spina-christi in the Tbilisi environs (East Georgia, South Caucasus

    Directory of Open Access Journals (Sweden)

    N.J. Lachashvili

    2018-06-01

    Full Text Available Christ's thorn formation (Paliureta spina-christi of Tbilisi environs is studied. This formation is one of the typical representatives of hemixerophilous shrubberies of shibliak type in the Caucasus region and one of the characteristic for vegetation cover of Tbilisi surroundings. Plant communities of Christ's thorn formation with different plots area are fragmentary spread almost all over the territory of Tbilisi environs from 400 to 800 (900 m above s.l.. Plant communities are developed on slopes and plane place with various exposure and inclination, mainly on the grey-cinnamonic and cinnamonic soils. The most xerophilous variants are developed on the erosive bare mother rocks as well. In Tbilisi environs the Christ-thorn's plant communities are either primary or secondary origin. Formation is characterized by rich typological and floristic composition. We identified 6 plant communities: (1 Paliureto-mixtofruticetum gramino-mixtoherbosum, (2 Paliureto-Rhmanetum gramino-mixtoherbosum, (3 Paliureto gramino-mixtoherbosum, (4 Paliureto bothriochlooso gramino-mixtoherbosum, (5 Paliuretum festuceto-bothriochloosum, (6 Paliureto-Astragaleto-Rhamnetum. For each separated plant communities the basic structural characteristics (general projective coverage, projective coverage, distribution and height of layers, sodding degree, dominant-edificator plants, characteristic species, number of species, moss cover, litter, species richness, spectrum of life forms, distribution area in the Tbilisi environs and main physical-geographical conditions (topography, altitude, exposure, inclination, soil type are given. 190 species of vascular plants, which belong to 40 families and 132 genera, were recorded. In the floristic spectrum leading families are: 1. Poaceae – 27 species (14,2%, 2. Asteraceae – 25 species (13,2%, 3. Fabaceae – 17 species (8,9%, 4-5. Lamiaceae and Rosaceae – 15-15 species (7,9-7,9%, 6-8. Apiaceae, Caryophyllaceae and Rubiaceae – 8

  4. La expulsión de las representaciones del templo (los Autos Sacramentales y la crisis del Corpus de Toledo, 1613-1645

    Directory of Open Access Journals (Sweden)

    Fernando Martínez Gil

    2006-12-01

    Full Text Available Some of Calderón de la Barca’s sacramental plays were premiered in Toledo, but they were never performed inside the Cathedral, as in the previous centuries. On the contrary, they were shown on a stage in the city square, opposite the town hall building. A few years earlier, between 1614 and 1617, and after an intense debate, the Cathedral canons had decided to break the tradition and expel the plays from inside the temple. This fact is not just an anecdote; it reflects an interesting change in mentalities and in the way in which religiousness and feasts were now understood. The plays were an essential element in the Feast of Corpus Christi; nevertheless, in the 17th century, religious spaces were no longer considered appropiate. Those plays were definitely forbidden in the 18th century.

  5. 75 FR 55968 - Special Local Regulations, Sabine River; Orange, TX

    Science.gov (United States)

    2010-09-15

    ...-AA08 Special Local Regulations, Sabine River; Orange, TX AGENCY: Coast Guard, DHS. ACTION: Temporary... Arthur Captain of the Port Zone on the Sabine River, Orange, Texas. This Special Local Regulation is... River, Orange, TX in the Federal Register (75 FR 41119). We received no comments on the proposed rule...

  6. 75 FR 41119 - Special Local Regulations; Sabine River, Orange, TX

    Science.gov (United States)

    2010-07-15

    ...-AA08 Special Local Regulations; Sabine River, Orange, TX AGENCY: Coast Guard, DHS. ACTION: Notice of... the Port Arthur Captain of the Port Zone on the Sabine River, Orange, Texas. This Special Local... Orange, TX, Thunder on the Sabine boat races. The powerboat race and associated testing will occur...

  7. 76 FR 30890 - Special Local Regulations; Sabine River, Orange, TX

    Science.gov (United States)

    2011-05-27

    ...-AA08 Special Local Regulations; Sabine River, Orange, TX AGENCY: Coast Guard, DHS. ACTION: Notice of... the Port Arthur Captain of the Port Zone on the Sabine River, Orange, Texas on September 24-25, 2011... race in conjunction with the Orange, TX S.P.O.R.T. boat races. The powerboat race and associated...

  8. 78 FR 48294 - Amendment of Class E Airspace; Mason, TX

    Science.gov (United States)

    2013-08-08

    ...-1141; Airspace Docket No. 12-ASW-12] Amendment of Class E Airspace; Mason, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Mason, TX... Approach Procedures at Mason County Airport. This action enhances the safety and management of Instrument...

  9. 78 FR 48298 - Amendment of Class E Airspace; Commerce, TX

    Science.gov (United States)

    2013-08-08

    ...-0269; Airspace Docket No. 13-ASW-3] Amendment of Class E Airspace; Commerce, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Commerce, TX. Additional controlled airspace is necessary to accommodate new Area Navigation (RNAV...

  10. Corpus callosum lipoma with frontal encephalocele

    International Nuclear Information System (INIS)

    Srinivasa Rao, A.; Rao, V.R.K.; Ravi Mandalam, K.; Gupta, A.K.; Kumar, S.; Joseph, S.; Unni, M.

    1990-01-01

    Computed tomographic and plain X-ray observations in a patient with corpus callosum lipoma associated with frontal encephalocele are reported. The rarity of the lesion and the specific diagnostic criteria on CT are emphasised. (orig.)

  11. [Medicine and astrology in Arnau's corpus].

    Science.gov (United States)

    Giralt, Sebastià

    2006-01-01

    The role of astrology in Arnau de Vilanova's medical work is revisited with special attention to the problems of authorship posed by the astrological writings of Arnau's corpus and to their hypothetical chronology.

  12. Institutions and Social Change: implementing co-operative housing and environmentally sustainable development at Christie Walk

    Directory of Open Access Journals (Sweden)

    Susan McClean

    2009-09-01

    Full Text Available How can institutions contribute to the building of civil society in the twenty- first century? It is clear that the old laissez-faire approach and the more recent neo-conservative reliance on the market have failed to deliver housing for many people. On the other hand the state-based welfare housing model espoused by the Australian Labor Party over the twentieth century has also been beset by problems. Social alienation, and the crisis in affordable housing make the case that individualist approaches to urban living are not working. More communal solutions are needed - solutions attuned to a complex view of civil society outlined by Michael Edwards' tripartite definition. At the same time the onset of global warming now prompts Australians to create more environmentally sustainable ways of living. Addressing the theme of responsibility, this paper focuses on citizenship in its broader environmental, social and active forms. It analyses interviews and documentary evidence concerning the planning and development of Christie Walk, an innovative, medium density eco-city development in Adelaide. The investigation reveals the effects of some Australian institutions on residents' efforts to live socially and environmentally sustainable lives in an urban environment. The paper offers transdisciplinary research and analysis, linking the fields of history, urban housing, community development and environmental theory.

  13. Conducting a user-centered information needs assessment: the Via Christi Libraries' experience.

    Science.gov (United States)

    Perley, Cathy M; Gentry, Camillia A; Fleming, A Sue; Sen, Kristin M

    2007-04-01

    The research sought to provide evidence to support the development of a long-term strategy for the Via Christi Regional Medical Center Libraries. An information needs assessment was conducted in a large medical center serving approximately 5,900 physicians, clinicians, and nonclinical staff in 4 sites in 1 Midwestern city. Quantitative and qualitative data from 1,295 self-reporting surveys, 75 telephone interviews, and 2 focus groups were collected and analyzed to address 2 questions: how could the libraries best serve their patrons, given realistic limitations on time, resources, and personnel, and how could the libraries best help their institution improve patient care and outcomes? Clinicians emphasized the need for "just in time" information accessible at the point of care. Library nonusers emphasized the need to market library services and resources. Both clinical and nonclinical respondents emphasized the need for information services customized to their professional information needs, preferences, and patterns of use. Specific information needs in the organization were identified. The results of this three-part, user-centered information needs assessment were used to develop an evidence-based strategic plan. The findings confirmed the importance of promoting library services in the organization and suggested expanded, collaborative roles for hospital librarians.

  14. Hanford Single Shell Tank Leak Causes and Locations - 241-TX Farm

    Energy Technology Data Exchange (ETDEWEB)

    Girardot, C. L.; Harlow, D> G.

    2014-07-22

    This document identifies 241-TX Tank Farm (TX Farm) leak causes and locations for the 100 series leaking tanks (241-TX-107 and 241-TX-114) identified in RPP-RPT-50870, Rev. 0, Hanford 241-TX Farm Leak Inventory Assessment Report. This document satisfies the TX Farm portion of the target (T04) in the Hanford Federal Facility Agreement and Consent Order milestone M-045-91F.

  15. 76 FR 70365 - Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund Federal...

    Science.gov (United States)

    2011-11-14

    ... 3206-AM50 Prevailing Rate Systems; Redefinition of the Austin, TX and Waco, TX, Appropriated Fund... the Federal Prevailing Rate Advisory Committee to best match the counties proposed for redefinition to... Prevailing Rate Advisory Committee (FPRAC), the national labor-management committee responsible for advising...

  16. Anatomy of the Rise and Fall of a Price-Fixing Conspiracy: Auctions at Sotheby's and Christie's

    OpenAIRE

    Ashenfelter, Orley C; Graddy, Kathryn

    2004-01-01

    The Sotheby's/Christie's price-fixing scandal that ended in the public trial of Alfred Taubman provides a unique window on a number of key economic and antitrust policy issues related to the use of the auction system. The trial provided detailed evidence as to how the price fixing worked, and the economic conditions under which it was started and began to fall apart. The outcome of the case also provides evidence on the novel auction process used to choose the lead counsel for the civil settl...

  17. RadNet Air Data From Austin, TX

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Austin, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  18. RadNet Air Data From Houston, TX

    Science.gov (United States)

    This page presents radiation air monitoring and air filter analysis data for Houston, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  19. TX-RX isolation method based on polarization diversity, spatial diversity and TX beamforming

    DEFF Research Database (Denmark)

    Foroozanfard, Ehsan; Carvalho, Elisabeth De; Pedersen, Gert F.

    2016-01-01

    In this paper, the feasibility of an antenna isolation technique based on null-steer beamforming, polarization diversity and spatial diversity is investigated. The proposed system consists of six patch antennas which are fed by a feeding network to obtain a null-steer beamformer. To achieve spatial...... diversity, antenna elements are located on two layers, facing in a different direction. Moreover, the antenna elements in two layers use different polarization. The measured results of the antenna system present a high TX-RX isolation in the order of 70 dB which shows the feasibility of such a system...

  20. Bayesian stratified sampling to assess corpus utility

    Energy Technology Data Exchange (ETDEWEB)

    Hochberg, J.; Scovel, C.; Thomas, T.; Hall, S.

    1998-12-01

    This paper describes a method for asking statistical questions about a large text corpus. The authors exemplify the method by addressing the question, ``What percentage of Federal Register documents are real documents, of possible interest to a text researcher or analyst?`` They estimate an answer to this question by evaluating 200 documents selected from a corpus of 45,820 Federal Register documents. Bayesian analysis and stratified sampling are used to reduce the sampling uncertainty of the estimate from over 3,100 documents to fewer than 1,000. A possible application of the method is to establish baseline statistics used to estimate recall rates for information retrieval systems.

  1. arTenTen: Arabic Corpus and Word Sketches

    Directory of Open Access Journals (Sweden)

    Tressy Arts

    2014-12-01

    The article also presents the ‘sketch grammar’ (the basis for the word sketches in detail, describes the process of building and processing the corpus, and considers the role of the corpus in additional research on Arabic.

  2. Divergent Approaches to Corpus Processing: The Need for ...

    African Journals Online (AJOL)

    Riette Ruthven

    McEnery and Wilson (1996: 32) stress the importance of a corpus: 'As a stan- ... close to five million running words, and the Ndebele corpus at around three ... since their introduction and reinforcement through the second form of contact.

  3. Rheumatic diseases in the Corpus Hippocraticum

    Directory of Open Access Journals (Sweden)

    G. Squillace

    2011-09-01

    Full Text Available Medecine of V and IV centuries B.C. attested in the Corpus Hippocraticum ascribes all diseases to the rheuma, i.e. the flux of humours into the body. This flux produces not only the rise of cold, hoarsness, cough, reddenings, dropsy, but also arthritis, sciatica, gout.

  4. The Yale-Classical Archives Corpus

    Directory of Open Access Journals (Sweden)

    Christopher William White

    2016-07-01

    Full Text Available The Yale-Classical Archives Corpus (YCAC contains harmonic and rhythmic information for a dataset of Western European Classical art music. This corpus is based on data from classicalarchives.com, a repository of thousands of user-generated MIDI representations of pieces from several periods of Western European music history. The YCAC makes available metadata for each MIDI file, as well as a list of pitch simultaneities ("salami slices" in the MIDI file. Metadata include the piece's composer, the composer's country of origin, date of composition, genre (e.g., symphony, piano sonata, nocturne, etc., instrumentation, meter, and key. The processing step groups the file's pitches into vertical slices each time a pitch is added or subtracted from the texture, recording the slice's offset (measured in the number of quarter notes separating the event from the file's beginning, highest pitch, lowest pitch, prime form, scale-degrees in relation to the global key (as determined by experts, and local key information (as determined by a windowed key-profile analysis. The corpus contains 13,769 MIDI files by 571 composers yielding over 14,051,144 vertical slices. This paper outlines several properties of this corpus, along with a representative study using this dataset.

  5. Inflation Metaphor in the TIME Magazine Corpus

    Science.gov (United States)

    Hu, Chunyu; Liu, Huijie

    2016-01-01

    A historical perspective on economy metaphor can shed new lights on economic thoughts. Based on the TIME Magazine Corpus (TMC), this paper investigates inflation metaphor over 83 years and compares findings against the economic data over the relatively corresponding period. The results show how inflation, an abstract concept and a normal economic…

  6. Sirenomelia with agenesis of corpus callosum.

    Science.gov (United States)

    Shirani, Shapour; Rekabi, Vahab; Kamalian, Naser

    2006-07-01

    Sirenomelia is a very rare anomaly presented with fusion of the lower limbs. Genitourinary, neural tube, and vertebral anomalies are found in most cases. We report a case of sirenomelia with agenesis of corpus callosum, which has not been reported previously.

  7. Topics in Corpus-Based Dutch Syntax

    NARCIS (Netherlands)

    Beek, Leonoor Johanneke van der

    2005-01-01

    In this dissertation, corpus data is applied in various kinds of linguistic analyses. The data serves as a source of examples and counterexamples in a theoretical linguistic analysis of the Dutch cleft construction, as the source of quantitative data in a probabilistic account of the dative

  8. Concept annotation in the CRAFT corpus.

    Science.gov (United States)

    Bada, Michael; Eckert, Miriam; Evans, Donald; Garcia, Kristin; Shipley, Krista; Sitnikov, Dmitry; Baumgartner, William A; Cohen, K Bretonnel; Verspoor, Karin; Blake, Judith A; Hunter, Lawrence E

    2012-07-09

    Manually annotated corpora are critical for the training and evaluation of automated methods to identify concepts in biomedical text. This paper presents the concept annotations of the Colorado Richly Annotated Full-Text (CRAFT) Corpus, a collection of 97 full-length, open-access biomedical journal articles that have been annotated both semantically and syntactically to serve as a research resource for the biomedical natural-language-processing (NLP) community. CRAFT identifies all mentions of nearly all concepts from nine prominent biomedical ontologies and terminologies: the Cell Type Ontology, the Chemical Entities of Biological Interest ontology, the NCBI Taxonomy, the Protein Ontology, the Sequence Ontology, the entries of the Entrez Gene database, and the three subontologies of the Gene Ontology. The first public release includes the annotations for 67 of the 97 articles, reserving two sets of 15 articles for future text-mining competitions (after which these too will be released). Concept annotations were created based on a single set of guidelines, which has enabled us to achieve consistently high interannotator agreement. As the initial 67-article release contains more than 560,000 tokens (and the full set more than 790,000 tokens), our corpus is among the largest gold-standard annotated biomedical corpora. Unlike most others, the journal articles that comprise the corpus are drawn from diverse biomedical disciplines and are marked up in their entirety. Additionally, with a concept-annotation count of nearly 100,000 in the 67-article subset (and more than 140,000 in the full collection), the scale of conceptual markup is also among the largest of comparable corpora. The concept annotations of the CRAFT Corpus have the potential to significantly advance biomedical text mining by providing a high-quality gold standard for NLP systems. The corpus, annotation guidelines, and other associated resources are freely available at http://bionlp-corpora.sourceforge.net/CRAFT/index.shtml.

  9. KoralQuery -- A General Corpus Query Protocol

    DEFF Research Database (Denmark)

    Bingel, Joachim; Diewald, Nils

    2015-01-01

    . In this paper, we present KoralQuery, a JSON-LD based general corpus query protocol, aiming to be independent of particular QLs, tasks and corpus formats. In addition to describing the system of types and operations that KoralQuery is built on, we exemplify the representation of corpus queries in the serialized...

  10. Using a Corpus in a 300-Level Spanish Grammar Course

    Science.gov (United States)

    Benavides, Carlos

    2015-01-01

    The present study examined the use and effectiveness of a large corpus--the Corpus del Español (Davies, 2002)--in a 300-level Spanish grammar university course. Students conducted hands-on corpus searches with the goal of finding concordances containing particular types of collocations (combinations of words that tend to co-occur) and tokens (any…

  11. The Nordic Dialect Corpus – a joint research infrastructure

    Directory of Open Access Journals (Sweden)

    Janne Bondi Johannessen

    2011-06-01

    Full Text Available The paper describes the Nordic Dialect Corpus as of June 2010. The corpus is a tool that combines a number of useful features that together makes it a unique and very advanced resource for researchers of many fields of language search. The corpus is web-based and features full audio-visual representation linked to transcriptions and translations.

  12. Dictionary Writing System (DWS) + Corpus Query Package (CQP ...

    African Journals Online (AJOL)

    In this article the integrated corpus query functionality of the dictionary compilation software TshwaneLex is analysed. Attention is given to the handling of both raw corpus data and annotated corpus data. With regard to the latter it is shown how, with a minimum of human effort, machine learning techniques can be employed ...

  13. Divergent approaches to corpus processing: the need for ...

    African Journals Online (AJOL)

    With a good corpus, data can be provided giving an authoritative body of linguistic evidence which can support generalisations and against which hypotheses can be tested. As this proves the invaluable status of a corpus, the article assesses the processing of the Shona corpus and discusses how some aspects of the ...

  14. Double-contained receiver tank 244-TX, grab samples, 244TX-97-1 through 244TX-97-3 analytical results for the final report

    International Nuclear Information System (INIS)

    Esch, R.A.

    1997-01-01

    This document is the final report for the double-contained receiver tank (DCRT) 244-TX grab samples. Three grabs samples were collected from riser 8 on May 29, 1997. Analyses were performed in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO). The analytical results are presented in a table

  15. Corpus-based Studies on Nursing Textbooks

    Directory of Open Access Journals (Sweden)

    Alif Fairus Nor Mohamad

    2013-07-01

    Full Text Available English for Specific Purposes (ESP educators often face dilemma in deciding what lexical items to teach their students. In the field of English for Nursing Purposes (ENP, there is no exception on this issue as well. Only by analyzing the nursing corpus made up of essential core textbooks that can provide better insights and guide to both nursing students and educators. This research aims to highlight the 2,000 most frequently used nursing words across the core textbooks of nursing and to profile the types of ‘low frequency’ lexis which comprise the nursing corpus in terms of the General Service List (GSL and Academic Word List (AWL lexis coverage. By knowing the frequently used nursing words would further reduce students’ reading deficiency if the students use the 2000-word list.

  16. The VGLC: The Video Game Level Corpus

    OpenAIRE

    Summerville, Adam James; Snodgrass, Sam; Mateas, Michael; Ontañón, Santiago

    2016-01-01

    Levels are a key component of many different video games, and a large body of work has been produced on how to procedurally generate game levels. Recently, Machine Learning techniques have been applied to video game level generation towards the purpose of automatically generating levels that have the properties of the training corpus. Towards that end we have made available a corpora of video game levels in an easy to parse format ideal for different machine learning and other game AI researc...

  17. Developing a corpus of spoken language variability

    Science.gov (United States)

    Carmichael, Lesley; Wright, Richard; Wassink, Alicia Beckford

    2003-10-01

    We are developing a novel, searchable corpus as a research tool for investigating phonetic and phonological phenomena across various speech styles. Five speech styles have been well studied independently in previous work: reduced (casual), careful (hyperarticulated), citation (reading), Lombard effect (speech in noise), and ``motherese'' (child-directed speech). Few studies to date have collected a wide range of styles from a single set of speakers, and fewer yet have provided publicly available corpora. The pilot corpus includes recordings of (1) a set of speakers participating in a variety of tasks designed to elicit the five speech styles, and (2) casual peer conversations and wordlists to illustrate regional vowels. The data include high-quality recordings and time-aligned transcriptions linked to text files that can be queried. Initial measures drawn from the database provide comparison across speech styles along the following acoustic dimensions: MLU (changes in unit duration); relative intra-speaker intensity changes (mean and dynamic range); and intra-speaker pitch values (minimum, maximum, mean, range). The corpus design will allow for a variety of analyses requiring control of demographic and style factors, including hyperarticulation variety, disfluencies, intonation, discourse analysis, and detailed spectral measures.

  18. Comparative studies of the endonucleases from two related Xenopus laevis retrotransposons, Tx1L and Tx2L: target site specificity and evolutionary implications.

    Science.gov (United States)

    Christensen, S; Pont-Kingdon, G; Carroll, D

    2000-01-01

    In the genome of the South African frog, Xenopus laevis, there are two complex families of transposable elements, Tx1 and Tx2, that have identical overall structures, but distinct sequences. In each family there are approximately 1500 copies of an apparent DNA-based element (Tx1D and Tx2D). Roughly 10% of these elements in each family are interrupted by a non-LTR retrotransposon (Tx1L and Tx2L). Each retrotransposon is flanked by a 23-bp target duplication of a specific D element sequence. In earlier work, we showed that the endonuclease domain (Tx1L EN) located in the second open reading frame (ORF2) of Tx1L encodes a protein that makes a single-strand cut precisely at the expected site within its target sequence, supporting the idea that Tx1L is a site-specific retrotransposon. In this study, we express the endonuclease domain of Tx2L (Tx2L EN) and compare the target preferences of the two enzymes. Each endonuclease shows some preference for its cognate target, on the order of 5-fold over the non-cognate target. The observed discrimination is not sufficient, however, to explain the observation that no cross-occupancy is observed - that is, L elements of one family have never been found within D elements of the other family. Possible sources of additional specificity are discussed. We also compare two hypotheses regarding the genome duplication event that led to the contemporary pseudotetraploid character of Xenopus laevis in light of the Tx1L and Tx2L data.

  19. 76 FR 19276 - Television Broadcasting Services; El Paso, TX

    Science.gov (United States)

    2011-04-07

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 11-4; RM-11616, DA 11-530] Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications Commission. ACTION: Final rule... Part 73 Television. Federal Communications Commission. Barbara A. Kreisman, Chief, Video Division...

  20. 75 FR 9859 - Television Broadcasting Services; Beaumont, TX

    Science.gov (United States)

    2010-03-04

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 10-307; MB Docket No. 10-49; RM-11593] Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications Commission. ACTION: Proposed... 73 Television, Television broadcasting. For the reasons discussed in the preamble, the Federal...

  1. 75 FR 19907 - Television Broadcasting Services; Beaumont, TX

    Science.gov (United States)

    2010-04-16

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 10-606; MB Docket No. 10-49; RM-11593] Television Broadcasting Services; Beaumont, TX AGENCY: Federal Communications Commission. ACTION: Final rule... Congressional review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television, Television...

  2. 76 FR 44280 - Television Broadcasting Services; El Paso, TX

    Science.gov (United States)

    2011-07-25

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 11-74; RM-11630, DA 11-1185] Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications Commission. ACTION: Final rule... U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television. Federal Communications...

  3. 76 FR 28946 - Television Broadcasting Services; El Paso, TX

    Science.gov (United States)

    2011-05-19

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 11-74, RM-11630; DA 11-746] Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications Commission. ACTION: Proposed... of Subjects in 47 CFR Part 73 Television Federal Communications Commission. Barbara A. Kreisman...

  4. 76 FR 5120 - Television Broadcasting Services; El Paso, TX

    Science.gov (United States)

    2011-01-28

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [DA 11-74; MB Docket No. 11-4; RM-11616] Television Broadcasting Services; El Paso, TX AGENCY: Federal Communications Commission. ACTION: Proposed... 73 Television, Television broadcasting. For the reasons discussed in the preamble, the Federal...

  5. The Ndebele Language Corpus: A Review of Some Factors Influencing the Content of the Corpus*

    Directory of Open Access Journals (Sweden)

    Samukele Hadebe

    2011-10-01

    Full Text Available

    Abstract: The Ndebele language corpus described here is that compiled by the ALLEX Project (now ALRI at the University of Zimbabwe. It is intended to reflect as much as possible the Ndebele language as spoken in Zimbabwe. The Ndebele language corpus was built in order to provide much-needed material for the study of the Ndebele language with a special focus on dictionarymaking and research. Like most corpora, the Ndebele language corpus may in future be used for other purposes not thought of at the time of its inception. It has been designed to meet generally acceptable standards so that it can be adaptable to various possible uses by various researchers. The article wants to outline the building process of the Ndebele language corpus with special emphasis on the challenges that faced compilers, and possible solutions. It is assumed that some of these challenges might not be peculiar to Ndebele alone but could also affect related African languages in a more or less similar situation. The main focus of the discussion will be the composition of the Ndebele language corpus, i.e. the type of texts that constitute the corpus. The corpus is composed of published texts, unpublished texts and oral material gathered from Ndebele-speaking districts of Zimbabwe. It will be argued that the use of the corpus and its reliability for research depends among other factors on its contents. It will also be shown that the contents of a corpus depend on a number of factors, some of which include sociolinguistic, political and economic considerations. These considerations have implications on both the content and quality of published and oral texts that constitute the Ndebele language corpus.

    Keywords: CORPUS, ORAL MATERIALS, CODE-MIXING, CODE-SWITCHING, MOTHER- TONGUE, NDEBELE

    Opsomming: Die Ndebeletaalkorpus: 'n Oorsig van sommige faktore wat die inhoud van die korpus be?nvloed. Die Ndebeletaalkorpus wat hier beskryf word, is di? saamgestel deur die

  6. Diffuse corpus callosum infarction - Rare vascular entity with differing etiology.

    Science.gov (United States)

    Mahale, Rohan; Mehta, Anish; Buddaraju, Kiran; John, Aju Abraham; Javali, Mahendra; Srinivasa, Rangasetty

    2016-01-15

    Infarctions of the corpus callosum are rare vascular events. It is relatively immune to vascular insult because of its rich vascular supply from anterior and posterior circulations of brain. Report of 3 patients with largely diffuse acute corpus callosum infarction. 3 patients with largely diffuse acute corpus callosum infarction were studied and each of these 3 patients had 3 different aetiologies. The 3 different aetiologies of largely diffuse acute corpus callosum infarction were cardioembolism, tuberculous arteritis and takayasu arteritis. Diffuse corpus callosum infarcts are rare events. This case series narrates the three different aetiologies of diffuse acute corpus callosum infarction which is a rare vascular event. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. 75 FR 15360 - Proposed Amendment of Class E Airspace; Austin, TX

    Science.gov (United States)

    2010-03-29

    ...-1152; Airspace Docket No. 09-ASW-31] Proposed Amendment of Class E Airspace; Austin, TX AGENCY: Federal... proposes to amend Class E airspace in the Austin, TX area. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Austin Executive Airport, Austin, TX. The...

  8. TxDOT can help pave the way for distribution centers.

    Science.gov (United States)

    2010-05-01

    TxDOT supports economic development in Texas. : Working through its district offices, TxDOT can help : developers avoid common transportation-related : problems associated with selected center sites. TxDOT : may also be able to help distribution cent...

  9. 75 FR 6319 - Proposed Amendment of Low Altitude Area Navigation Route T-254; Houston, TX

    Science.gov (United States)

    2010-02-09

    ... Amendment of Low Altitude Area Navigation Route T-254; Houston, TX AGENCY: Federal Aviation Administration... altitude Area Navigation (RNAV) route T-254 in the Houston, TX, terminal area by eliminating the segment... safety and the efficient use of the navigable airspace in the Houston, TX, terminal area. DATES: Comments...

  10. 75 FR 18047 - Amendment of Low Altitude Area Navigation Route T-254; Houston, TX

    Science.gov (United States)

    2010-04-09

    ...-254; Houston, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends low altitude Area Navigation (RNAV) route T-254 in the Houston, TX, terminal area by... Houston, TX, terminal area. DATES: Effective Dates: 0901 UTC, June 3, 2010. The Director of the Federal...

  11. 75 FR 64972 - Proposed Revocation of Class E Airspace; Lone Star, TX

    Science.gov (United States)

    2010-10-21

    ...-0772; Airspace Docket No. 10-ASW-10] Proposed Revocation of Class E Airspace; Lone Star, TX AGENCY... action proposes to remove Class E airspace at Lone Star, TX. Abandonment of the former Lone Star Steel... need for controlled airspace in the Lone Star, TX, area. The FAA is taking this action to ensure the...

  12. Corpus callosum demyelination associated with acquired stuttering.

    Science.gov (United States)

    Decker, Barbara McElwee; Guitar, Barry; Solomon, Andrew

    2018-04-21

    Compared with developmental stuttering, adult onset acquired stuttering is rare. However, several case reports describe acquired stuttering and an association with callosal pathology. Interestingly, these cases share a neuroanatomical localisation also demonstrated in developmental stuttering. We present a case of adult onset acquired stuttering associated with inflammatory demyelination within the corpus callosum. This patient's disfluency improved after the initiation of immunomodulatory therapy. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Spontal-N: A Corpus of Interactional Spoken Norwegian

    OpenAIRE

    Sikveland, A.; Öttl, A.; Amdal, I.; Ernestus, M.; Svendsen, T.; Edlund, J.

    2010-01-01

    Spontal-N is a corpus of spontaneous, interactional Norwegian. To our knowledge, it is the first corpus of Norwegian in which the majority of speakers have spent significant parts of their lives in Sweden, and in which the recorded speech displays varying degrees of interference from Swedish. The corpus consists of studio quality audio- and video-recordings of four 30-minute free conversations between acquaintances, and a manual orthographic transcription of the entire material. On basis of t...

  14. Learner corpus profiles the case of Romanian learner English

    CERN Document Server

    Chitez, Madalina

    2014-01-01

    The first three chapters of the book offer relevant information on the new methodological approach, learner corpus profiling, and the exemplifying case, Romanian Learner English. The description of the Romanian Corpus of Learner English is also given special attention. The following three chapters include corpus-based frequency analyses of selected grammatical categories (articles, prepositions, genitives), combined with error analyses. In the concluding discussion, the book summarizes the features compiled as lexico-grammatical profiles.

  15. GECO, un Gestor de Corpus colaborativo basado en web

    Directory of Open Access Journals (Sweden)

    Gerardo Sierra

    2017-12-01

    Full Text Available Este artículo presenta GEstor de COrpus (GECO, un software de gestión de corpus en línea que permite a los usuarios subir colecciones de documentos y volverlos corpus digitales. En el sistema, los corpus pueden ser procesados por otras aplicaciones, las cuales están implementadas como módulos integrados a la infraestructura de GECO. En este documento se describen a detalle sus características, así como la funcionalidad del generador de concordancias desarrollado en torno a él.

  16. [Behavioral and cognitive profile of corpus callosum agenesia - Review].

    Science.gov (United States)

    Lábadi, Beatrix; Beke, Anna Maria

    2016-11-30

    Agenesis of corpus callosum is a relatively frequent congenital cerebral malformation including dysplasia, total or partial absence of corpus callosum. The agenesis of corpus callosum can be occured in isolated form without accompanying somatic or central nervous system abnormalities and it can be associated with other central nervus system malformations. The behavioral and cognitive outcome is more favorable for patients with isolated agenesis of corpus callous than syndromic form of corpus callosum. The aim of this study is to review recent research on behavioral and social-cognitive functions in individuals with agenesis of corpus callosum. Developmental delay is common especially in higher-order cognitive and social functions. An internet database search was performed to identify publications on the subject. Fifty-five publications in English corresponded to the criteria. These studies reported deficits in language, social cognition and emotions in individuals with agenesis of corpus callosum which is known as primary corpus callous syndrome. The results indicate that individuals with agenesis of corpus callosum have deficiency in social-cognitive domain (recognition of emotions, weakness in paralinguistic aspects of language and mentalizing abilities). The impaired social cognition can be manifested in behavioral problems like autism and attention deficit hyperactivity disorder.

  17. What Does Corpus Linguistics Have to Offer to Language Assessment?

    Science.gov (United States)

    Xi, Xiaoming

    2017-01-01

    In recent years, continuing advances in technology have increased the capacity to automate the extraction of a range of linguistic features of texts and thus have provided the impetus for the substantial growth of corpus linguistics. While corpus linguistic tools and methods have been used extensively in second language learning research, they…

  18. Comparative study on corpus development for Malay investment ...

    African Journals Online (AJOL)

    Comparative study on corpus development for Malay investment fraud detection in website. ... Journal of Fundamental and Applied Sciences ... The aim of this research is to develop a corpus for Malay investment fraud so that it can be used in ...

  19. The Shona Corpus and the Problem of Tagging | Chabata | Lexikos

    African Journals Online (AJOL)

    An analysis of the problems that most corpus builders face shows that more problems are likely to be encountered when dealing with spoken corpora than with written corpora. The paper demonstrates that tagging is an important component of corpus building as it makes it easier for a researcher to extract relevant data.

  20. DutchParl: A corpus of parliamentary documents in Dutch

    NARCIS (Netherlands)

    Marx, M.; Schuth, A.

    2010-01-01

    A corpus called DutchParl is created which aims to contain all digitally available parliamentary documents written in the Dutch language. The first version of DutchParl contains documents from the parliaments of The Netherlands, Flanders and Belgium. The corpus is divided along three dimensions: per

  1. MR measurement of normal corpus callosum in children

    International Nuclear Information System (INIS)

    Kim, Hyoung Sub; Kim, Jong Chul; Kang, Yong Soo; Lee, Young Hwan; Kim, Young Wol

    1997-01-01

    To measure the mean size of the various portions of the corpus callosum in normal Korean children, using MR imaging. Our subjects were 166 children (male : female=100 : 66) aged under 15 whose findings on MR imaging and neurologic examination were normal. Using midsagittal T1-weighted imaging, we measured the length of the brain and corpus callosum, the height of the latter, and the thickness of its genu body, transitional zone and splenium. The measurements were statistically analysed according to age and sex. Brain length and the size of the various portions of the corpus callosum tended to increase relatively rapidly during the first three years of life, but the rate of growth tended to decrease according to age. The mean lenght of the brain and corpus callosum and the mean thickness of the splenium of the corpus callosum did not differ according to sex. The mean thickness of the genu, body and transitional zone of the corpus callosum was greater in males than in females. The ratio of the length of the corpus callosum to the anteroposterior diameter of the brain was significantly greater in females than in males (alpha=0.05). Using MR imaging, we measured the mean sizes of the various portions of the corpus callosum in normal children;these values may provide a useful basis for determing changes occurring in its structure

  2. Use of "Google Scholar" in Corpus-Driven EAP Research

    Science.gov (United States)

    Brezina, Vaclav

    2012-01-01

    This primarily methodological article makes a proposition for linguistic exploration of textual resources available through the "Google Scholar" search engine. These resources ("Google Scholar virtual corpus") are significantly larger than any existing corpus of academic writing. "Google Scholar", however, was not designed for linguistic searches…

  3. Rotary mode core sampling approved checklist: 241-TX-113

    International Nuclear Information System (INIS)

    Fowler, K.D.

    1998-01-01

    The safety assessment for rotary mode core sampling was developed using certain bounding assumptions, however, those assumptions were not verified for each of the existing or potential flammable gas tanks. Therefore, a Flammable Gas/Rotary Mode Core Sampling Approved Checklist has been completed for tank 241-TX-113 prior to sampling operations. This transmittal documents the dispositions of the checklist items from the safety assessment

  4. Proton Testing of nVidia Jetson TX1

    Science.gov (United States)

    Wyrwas, Edward J.

    2017-01-01

    Single-Event Effects (SEE) testing was conducted on the nVidia Jetson TX1 System on Chip (SOC); herein referred to as device under test (DUT). Testing was conducted at Massachusetts General Hospitals (MGH) Francis H. Burr Proton Therapy Center on October 16th, 2016 using 200MeV protons. This testing trip was purposed to provide a baseline assessment of the radiation susceptibility of the DUT as no previous testing had been conducted on this component.

  5. Rotary mode core sampling approved checklist: 241-TX-116

    International Nuclear Information System (INIS)

    FOWLER, K.D.

    1999-01-01

    The safety assessment for rotary mode core sampling was developed using certain bounding assumptions, however, those assumptions were not verified for each of the existing or potential flammable gas tanks. Therefore, a Flammable Gas/Rotary Mode Core Sampling Approved Checklist has been completed for tank 241-TX-116 prior to sampling operations. This transmittal documents the dispositions of the checklist items from the safety assessment

  6. Morphometric changes of the corpus callosum in congenital blindness

    DEFF Research Database (Denmark)

    Tomaiuolo, Francesco; Campana, Serena; Collins, D Louis

    2014-01-01

    We examined the effects of visual deprivation at birth on the development of the corpus callosum in a large group of congenitally blind individuals. We acquired high-resolution T1-weighted MRI scans in 28 congenitally blind and 28 normal sighted subjects matched for age and gender....... There was no overall group effect of visual deprivation on the total surface area of the corpus callosum. However, subdividing the corpus callosum into five subdivisions revealed significant regional changes in its three most posterior parts. Compared to the sighted controls, congenitally blind individuals showed a 12......% reduction in the splenium, and a 20% increase in the isthmus and the posterior part of the body. A shape analysis further revealed that the bending angle of the corpus callosum was more convex in congenitally blind compared to the sighted control subjects. The observed morphometric changes in the corpus...

  7. Cytotoxicity of flavonoid glycosides, flavonoids and phenolic acids from Inula oculus-christi on mammalian cell lines

    Directory of Open Access Journals (Sweden)

    Ralitsa K. Veleva

    2016-12-01

    Full Text Available Herbs of the genus Inula are well known in traditional medicine. Their extracts are used as expectorants, antitussives, bactericides as well as for the treatment of lung inflammation and have shown to possess anti-inflammatory and secretolytic activity. Experimental research findings indicate the anti-tumor effect of certain components of extracts from Inula cappa and Inula britannicа and those from Inula racemosa have antimicrobial and antidiabetic activity. We have directed our efforts on investigating the effects of different extracts from Inula oculus-christi, enriched with certain groups of biologically active substances - flavonoid glycosides (A, phenolic acids (B, flavonoid glycosides and phenolic acids (C, flavonoids and phenolic acids (D. The effect of these extracts on normal (MDCK ІІ and RPE1 and carcinoma cell lines (A549 and HepG2 was evaluated. We have performed cytotoxicity study (crystal violet assay as well as morphological analysis of changes induced by the extracts. Among the tumor cell lines HepG2 show greater sensitivity. Surprisingly extract C has no significant influence on both cancer cell lines.

  8. Subluxation and semantics: a corpus linguistics study.

    Science.gov (United States)

    Budgell, Brian

    2016-06-01

    The purpose of this study was to analyze the curriculum of one chiropractic college in order to discover if there were any implicit consensus definitions of the term subluxation. Using the software WordSmith Tools, the corpus of an undergraduate chiropractic curriculum was analyzed by reviewing collocated terms and through discourse analysis of text blocks containing words based on the root 'sublux.' It was possible to identify 3 distinct concepts which were each referred to as 'subluxation:' i) an acute or instantaneous injurious event; ii) a clinical syndrome which manifested post-injury; iii) a physical lesion, i.e. an anatomical or physiological derangement which in most instances acted as a pain generator. In fact, coherent implicit definitions of subluxation exist and may enjoy broad but subconscious acceptance. However, confusion likely arises from failure to distinguish which concept an author or speaker is referring to when they employ the term subluxation.

  9. Cytokines and Angiogenesis in the Corpus Luteum

    Directory of Open Access Journals (Sweden)

    António M. Galvão

    2013-01-01

    Full Text Available In adults, physiological angiogenesis is a rare event, with few exceptions as the vasculogenesis needed for tissue growth and function in female reproductive organs. Particularly in the corpus luteum (CL, regulation of angiogenic process seems to be tightly controlled by opposite actions resultant from the balance between pro- and antiangiogenic factors. It is the extremely rapid sequence of events that determines the dramatic changes on vascular and nonvascular structures, qualifying the CL as a great model for angiogenesis studies. Using the mare CL as a model, reports on locally produced cytokines, such as tumor necrosis factor α (TNF, interferon gamma (IFNG, or Fas ligand (FASL, pointed out their role on angiogenic activity modulation throughout the luteal phase. Thus, the main purpose of this review is to highlight the interaction between immune, endothelial, and luteal steroidogenic cells, regarding vascular dynamics/changes during establishment and regression of the equine CL.

  10. From Business Corpus to Business Lexicon*

    Directory of Open Access Journals (Sweden)

    Li Lan

    2011-10-01

    Full Text Available

    Abstract: Language corpora are now indispensable to dictionary compilation. They help broaden the role of the dictionary from standardizing the vocabulary to recording a language. The trilingual corpus generated by the Hong Kong Polytechnic University gives a record of business languages used in Hong Kong. It differs from other corpora in that (1 it includes English, Chinese and Japanese; (2 it shows local characteristics; and (3 it focuses on a specific area (financial services, including banking, accounting, auditing, insurance and investment. The paper discusses various issues of setting up a tricorpus, and how to make full use of the data to generate a trilingual lexicon.

    Keywords: MULTILINGUAL, SPECIAL PURPOSE, CORPUS, LEXICON

    Opsomming: Van sakekorpus tot sakeleksikon. Taalkorpora is tans onontbeerlik virdie samestelling van woordeboeke. Hulle help om die rol van die woordeboek uit te brei vanaf diestandaardisering van die woordeskat tot die optekening van ‘n taal. Die drietalige korpus wat deurdie Hongkongse Politegniese Universiteit ontwikkel is, verskaf ‘n opgawe van die saketale wat inHongkong gebruik word. Dit verskil van ander korpora deurdat (1 dit Engels, Chinees and Japaneesinsluit; (2 dit plaaslike eienskappe vertoon; en (3 dit op 'n spesifieke gebied (finansiële dienste,insluitende bankwese, rekeningkunde, ouditering, versekering en belegging fokus. Die artikelbespreek verskillende aspekte van die totstandbrenging van 'n drietalige korpus, en hoe om vollegebruik te maak van die data om 'n drietalige leksikon te genereer.

    Sleutelwoorde: MEERTALIG, SPESIALE DOEL, KORPUS, LEKSIKON

  11. Metaphor and Corpus Linguistics Metáfora e linguística de corpus

    Directory of Open Access Journals (Sweden)

    Tony Berber Sardinha

    2011-01-01

    Full Text Available In this paper, I look at four different aspects of metaphor research from a corpus linguistic perspective, namely: (1 the lexicogrammar of metaphors, which refers to the patterning of linguistic metaphor revealed by corpus analysis; (2 metaphor probabilities, which is a facet of metaphor that emerges from frequency-based studies of metaphor; (3 dimensions of metaphor variation, or the search for systematic parameters of variation in metaphor use across different registers; and (4 automated metaphor retrieval, which relates to the development of software to help identify metaphors in corpora. I argue that these four aspects are interrelated, and that advances in one of them can drive changes in the others.Neste artigo discuto quarto aspectos da pesquisa sobre metáfora do ponto de vista da linguística de corpus: (1 a lexicogramática das metáforas, que se refere aos padrões da metáfora linguística revelados pela análise de corpus; (2 probabilidades metafóricas, que é uma faceta da metáfora que emerge a partir dos estudos relacionados à freqüência de metáforas; (3 dimensões da variação de metáforas, ou a busca por parâmetros sistemáticos de variação de uso de metáfora em diferentes gêneros; e (4 captura automática de metáfora, que está relacionada ao desenvolvimento de softwares que auxiliam na identificação de metáforas em corpora. I defendo que esses quatro aspectos são interrelacionados, e que progressos em um deles podem acarretar mudanças nos outros.

  12. Insights from a Learner Corpus as Opposed to a Native Corpus about Cohesive Devices in an Academic Writing Context

    Science.gov (United States)

    Ersanli, Ceylan Yangin

    2015-01-01

    This study reports on the insights from an EFL learner corpora (a total of 151 essays and 49,690 words) generated from essays collected over the years in a Turkish state university from freshmen students enrolling in the Advanced Writing course. The comparison of cohesive devices in the non-native corpus (NNC) with those in a native corpus (NC)…

  13. Sugarcane Aphid Population Growth, Plant Injury, and Natural Enemies on Selected Grain Sorghum Hybrids in Texas and Louisiana.

    Science.gov (United States)

    Brewer, Michael J; Gordy, John W; Kerns, David L; Woolley, James B; Rooney, William L; Bowling, Robert D

    2017-10-01

    In response to the 2013 outbreak of sugarcane aphid, Melanaphis sacchari (Zehntner) (Hemiptera: Aphididae), on sorghum, Sorghum bicolor (L.), in North America, experiments were conducted at three southern U.S. grain sorghum production locations (Corpus Christi, TX; Winnsboro, LA; Rosenberg, TX). The objectives were to authenticate yield decline on susceptible hybrids (2014 and 2015) and to measure aphid population growth and natural enemy prevalence on susceptible and resistant hybrids with similar genetic background (2014). Yield decline on susceptible hybrids (Tx 2752/Tx430 and DKS53-67) was more substantial when aphid population growth accelerated quickly and peaked above 300 aphids per leaf (50 to nearly 100% yield decline). Location and year variation in maximum aphid density and cumulative aphid-days was high, with doubling time values on the susceptible hybrids ranging between 3.9 and 7.9 d. On resistant Tx2752/Tx2783, leaf injury and yield decline were not seen or less severe than on its paired susceptible Tx2752/Tx430. Aphids declined on Tx2752/Tx2783 after initial colony establishment (Corpus Christi) or took about 60% longer to double in population size when compared with Tx2572/Tx430 (Winnsboro). The predominant natural enemy taxa were aphelinid mummies (Hymenoptera: Aphelinidae), ladybird beetles (Coleoptera: Coccinellidae), and sryphid flies (Diptera: Syrphidae), and they were more prevalent during flowering than prior to flowering. They were generally responsive to changes in aphid density of both susceptible and resistant hybrids, but variability points to need for further study. In future research, full season observations should continue as well as more detailed study of potential compatibility of sorghum resistance and biological control. © The Author 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Radiolabelling of phoneutria nigriventer spider toxin (Tx1): a tool to study its binding site

    International Nuclear Information System (INIS)

    Santos, Raquel Gouvea dos; Diniz, Carlos Roberto; Nascimento, Marta Cordeiro; Lima, Maria Elena de

    1996-01-01

    The neurotoxin Tx1, isolated from the venom of the South American spider Phoneutria nigriventer produces tail elevation and spastic paralysis of posterior limbs after intracerebral ventricular injection in mice. Tx1 also produces ileum contraction in bioassay. We have investigated the binding of radioiodinated-Tx1 ( 125 I-Tx1) on the preparation of myenteric plexus-longitudinal muscle membrane from guinea pig ileum (MPLM) as a tool to characterize the interaction of this neurotoxin with its site. The neurotoxin Tx1 was radioiodinated with Na 125 I by the lactoperoxidase method. 125 I-Tx1 specifically binds to a single class of noninteracting binding sites of high affinity (Kd= 3.5 x 10 -10 M) and low capacity (1.2 pmol/mg protein). The specific binding increased in parallel with the protein concentration. In competition experiments the ligands of ionic channels used (sodium, potassium and calcium) did not affect the binding of 125 I-Tx1 to MPLM neither did the cholinergic ligands (hemicholinium-3, hexamethonium, d-tubocurarine and atropine). Another neurotoxin (Tx2-6, one of the isoforms of Tx2 pool) decreased toxin with MPLM and showed that toxin has a specific and saturable binding site in guinea pig ileum and this binding site appears to be related to the Tx2 site. (author)

  15. Tank 241-TX-302C grab samples, 302C-TX-97-1A through 302C-TX-97-3B analytical results for the final report

    International Nuclear Information System (INIS)

    Esch, R.A.

    1998-01-01

    This document is the final report for tank 241-TX-302C grab samples. Six grabs samples (302C-TX-97-1A, 302C-TX-97-1B, 302C-TX-97-2A, 302C-TX-97-2B, 302C-TX-97-3A, and 302C-TX-97-3B) were collected from the catch tank level gauge riser on December 19, 1997. The ''A'' and ''B'' portions from each sample location were composited and analyses were performed on the composites in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1997) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Rev. 1: Fowler, 1995; Rev. 2: Mulkey and Miller, 1997). The analytical results are presented in Table 1. No notification limits were exceeded. Appearance and Sample Handling Attachment 1 is provided as a cross-reference for relating the tank farm customer identification numbers with the 222-S Laboratory sample numbers and the portion of sample analyzed. Table 2 provides the appearance information

  16. Tank 241-TX-302C grab samples 302C-TX-97-1A through 302C-TX-97-3B analytical results for the final report

    Energy Technology Data Exchange (ETDEWEB)

    Esch, R.A.

    1998-03-12

    This document is the final report for tank 241-TX-302C grab samples. Six grabs samples (302C-TX-97-1A, 302C-TX-97-1B, 302C-TX-97-2A, 302C-TX-97-2B, 302C-TX-97-3A, and 302C-TX-97-3B) were collected from the catch tank level gauge riser on December 19, 1997. The ``A`` and ``B`` portions from each sample location were composited and analyses were performed on the composites in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1997) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Rev. 1: Fowler, 1995; Rev. 2: Mulkey and Miller, 1997). The analytical results are presented in Table 1. No notification limits were exceeded. Appearance and Sample Handling Attachment 1 is provided as a cross-reference for relating the tank farm customer identification numbers with the 222-S Laboratory sample numbers and the portion of sample analyzed. Table 2 provides the appearance information.

  17. Holistic corpus-based dialectology Dialetologia holística baseada em corpus

    Directory of Open Access Journals (Sweden)

    Benedikt Szmrecsanyi

    2011-01-01

    Full Text Available This paper is concerned with sketching future directions for corpus-based dialectology. We advocate a holistic approach to the study of geographically conditioned linguistic variability, and we present a suitable methodology, 'corpusbased dialectometry', in exactly this spirit. Specifically, we argue that in order to live up to the potential of the corpus-based method, practitioners need to (i abandon their exclusive focus on individual linguistic features in favor of the study of feature aggregates, (ii draw on computationally advanced multivariate analysis techniques (such as multidimensional scaling, cluster analysis, and principal component analysis, and (iii aid interpretation of empirical results by marshalling state-of-the-art data visualization techniques. To exemplify this line of analysis, we present a case study which explores joint frequency variability of 57 morphosyntax features in 34 dialects all over Great Britain.Este artigo debruça-se sobre o esboço propositivo de futuras direções para a dialetologia baseada em corpus. Defendemos uma abordagem holística para o estudo da variabilidade linguística geograficamente condicionada, e apresentamos uma metodologia adequada para tal - a dialetometria baseada em corpus. Mais especificamente, defendemos que para que se obtenham todos os resultados esperados da metodologia de corpus, pesquisadores devem: (i abandonar seu foco exclusivo em traços linguísticos individuais em favor do estudo dos agregados de traços, (ii amparar-se em métodos computacionais avançados de técnicas de análise multivariada (tais como escalagem multidimensional, análise de clusters, e análise de componente principal, e (iii auxiliar a interpretação de resultados empíricos através da utilização do estado da arte em técnicas de visualização. A fim de exemplificarmos essa linha de análise, apresentamos um estudo de caso que explora a variabilidade da frequência agregada de 57 tra

  18. Computerized tomography of the traumatic hematoma in the corpus callosum

    International Nuclear Information System (INIS)

    Ogura, Koichiro; Yamamoto, Isao; Hara, Makoto; Suzuki, Yoshio; Nakane, Toshichi; Watanabe, Masao.

    1982-01-01

    The value of the computerized tomography (CT) in the diagnosis of the intracerebral hematoma has been well documented. However, there is little report about the CT findings of the hematoma of the corpus callosum. This report presents two cases of the traumatic hematoma in the corpus callosum and is discussed about their CT findings. Two patients, 52 year-old male and 40 year-old male, respectively, are the cases of blunt mechanical head trauma which were accompanied neither by skull fracture nor by scalp injury. In all these cases, the findings that hematoma occupied from the genu to the body of the corpus callosum were verified by surgery and the axial CT revealed the following two similar findings. First; the hematoma in the genu of the corpus callosum was shown as a cresent-shaped high density mass. This finding seems to be due to the following anatomical structure, that is, the genu of the corpus callosum is located just in front of the anterior horn of the lateral ventricles in the shape of the convex towards posteriorly. Second; as the midportion of the body of the corpus callosum tends to be appeared narrow in width between both lateral ventricles, the hematoma which extended from the genu towards the body of the corpus callosum was shown as a dumbbell-shaped high density mass. (author)

  19. New Advances in Corpus-based Lexicography*

    Directory of Open Access Journals (Sweden)

    Arvi Hurskainen

    2011-10-01

    Full Text Available

    Abstract: This article presents various approaches used in corpus-based computational lexico-graphy. A claim is made that in order for computational lexicography to be efficient, precise and comprehensive, it should utilize the method where the corpus text is first analysed, and the results of this analysis is then processed further to meet the needs of a dictionary. This method has several advantages, including high precision and recall, as well as the possibility to automate the process much further than with more traditional computational methods. The frequency list obtained by using the lemma (the equivalent of the headword as basis helps in selecting the words to be in-cluded in the dictionary. The approach is demonstrated through various phases by applying SALAMA (the Swahili Language Manager to the process. Manual work will be needed in the phase when examples of use are selected from the corpus, and possibly modified. However, the list of examples of use, arranged alphabetically according to the corresponding headword, can also be produced automatically. Thus the alphabetical list of headwords with examples of use is the mate-rial on which the lexicographer works manually. The article deals with problems encountered in compiling traditional printed dictionaries, and it excludes electronic dictionaries and thesauri.

    Keywords: LEXICOGRAPHY, DICTIONARY, LANGUAGE TECHNOLOGY, COMPUTA-TIONAL LINGUISTICS, AUTOMATIC COMPILATION, DICTIONARY TESTING, INFORMA-TION RETRIEVAL, MORPHOLOGICAL ANALYSIS, SEMANTIC ANALYSIS, DISAMBIGUA-TION, HEURISTICS

    Opsomming: Nuwe ontwikkelinge in korpusgebaseerde leksikografie. Hier-die artikel beskryf verskillende benaderings wat in korpusgebaseerde rekenaarleksikografie ge-bruik word. Daar word aangevoer dat vir rekenaarleksikografie om doelmatig, noukeurig en omvattend te wees, dit die metode behoort te gebruik waarby die korpusteks eers ontleed word, en die resultaat van hierdie ontleding dan verder

  20. Google and beyond : web-as-corpus methodologies for translators

    OpenAIRE

    Ferraresi, Adriano

    2009-01-01

    Aquest article fa un repàs als plantejaments actuals sobre l'ús del web com a corpus lingüístic i emfatitza els avantatges (així com els inevitables riscos) que aquests poden introduir en el treball del traductor. Per tal d'il•lustrar aquest punt, es mostra un exemple de les diferents maneres en què un corpus derivat del web es pot aplicar profitosament a una tasca de traducció especialitzada.. Este artículo estudia los planteamientos actuales sobre el uso de la web como corpus lingüístico...

  1. FTA Corpus: a parallel corpus of English and Spanish Free Trade Agreements for the study of specialized collocations

    Directory of Open Access Journals (Sweden)

    Pedro Patiño García

    2013-04-01

    Full Text Available This paper describes the Corpus of Free Trade Agreements (henceforth FTA, a specialized parallel corpus in English and Spanish from Europe and America and a smaller subcorpus in English-Norwegian and Spanish-Norwegian that was prepared and then aligned with Translation Corpus Aligner 2 (Hofland & Johansson, 1998. The data was taken from Free Trade Agreements. These agreements are specialized texts officially signed and ratified by several countries and blocks of countries in the last twenty years. Thus, FTAs are a rich repository for terminology and phraseology that is used in different fields of business activity throughout the world. The corpus contains around 1.37 million words in the English section and 1.48 million words in its Spanish counterpart, plus 60,000 words each in the Spanish-Norwegian and English-Norwegian subcorpus. The corpus is being used primarily to study the terms and specialized collocations that include these terms in this kind of specialized texts.Keywords: specialized collocation, specialized parallel corpus, corpus linguistics, Free Trade Agreement

  2. Tank 241-TX-113 rotary mode core sampling and analysis plan

    International Nuclear Information System (INIS)

    McCain, D.J.

    1998-01-01

    This sampling and analysis plan (SAP) identities characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for push mode core samples from tank 241-TX-113 (TX-113). The Tank Characterization Technical Sampling Basis document identities Retrieval, Pretreatment and Immobilization as an issue that applies to tank TX-113. As a result, a 150 gram composite of solids shall be made and archived for that program. This tank is not on a Watch List

  3. Paediatric Virology in the Hippocratic Corpus

    Science.gov (United States)

    Mammas, Ioannis N.; Spandidos, Demetrios A.

    2016-01-01

    Hippocrates (Island of Kos, 460 B.C.-Larissa, 370 B.C.) is the founder of the most famous Medical School of the classical antiquity. In acknowledgement of his pioneering contribution to the new scientific field of Paediatric Virology, this article provides a systematic analysis of the Hippocratic Corpus, with particular focus on viral infections predominating in neonates and children. A mumps epidemic, affecting the island of Thasos in the 5th century B.C., is described in detail. ‘Herpes’, a medical term derived from the ancient Greek word ‘ἕρπειν’, meaning ‘to creep’ or ‘crawl’, is used to describe the spreading of cutaneous lesions in both childhood and adulthood. Cases of children with exanthema ‘resembling mosquito bites’ are presented in reference to varicella or smallpox infection. A variety of upper and lower respiratory tract viral infections are described with impressive accuracy, including rhinitis, pharyngitis, tonsillitis, laryngitis, bronchiolitis and bronchitis. The ‘cough of Perinthos’ epidemic, an influenza-like outbreak in the 5th century B.C., is also recorded and several cases complicated with pneumonia or fatal outcomes are discussed. Hippocrates, moreover, describes conjunctivitis, otitis, lymphadenitis, meningoencephalitis, febrile convulsions, gastroenteritis, hepatitis, poliomyelitis and skin warts, along with proposed treatment directions. Almost 2,400 years later, Hippocrates' systematic approach and methodical innovations can inspire paediatric trainees and future Paediatric Virology subspecialists. PMID:27446241

  4. Architecture of the Corpus Spongiosum : An Anatomical Study

    NARCIS (Netherlands)

    Ottenhof, Sarah R; de Graaf, Petra; Soeterik, Timo F W; Neeter, Lidewij M F H; Zilverschoon, Marijn; Spinder, Matty; Bosch, J L H Ruud; Bleys, Ronald L A W; Heck-de Kort, Laetitia

    PURPOSE: Urethral reconstruction is performed for urethral stricture or hypospadias correction. Research on urethral tissue engineering is increasing. Because the corpus spongiosum is important to support the urethra, urethral tissue engineering should ideally be combined with reconstruction of a

  5. Tone realisation in a Yoruba speech recognition corpus

    CSIR Research Space (South Africa)

    Van Niekerk, D

    2012-05-01

    Full Text Available development. Extracted contours are processed and analysed statistically to describe acoustic properties in different tonal contexts. The authors demonstrate how features useful for tone recognition or synthesis can be successfully extracted from a corpus...

  6. A massively parallel corpus: the Bible in 100 languages.

    Science.gov (United States)

    Christodouloupoulos, Christos; Steedman, Mark

    We describe the creation of a massively parallel corpus based on 100 translations of the Bible. We discuss some of the difficulties in acquiring and processing the raw material as well as the potential of the Bible as a corpus for natural language processing. Finally we present a statistical analysis of the corpora collected and a detailed comparison between the English translation and other English corpora.

  7. Clinical significance of the corpus callosum in cerebral palsy

    International Nuclear Information System (INIS)

    Lee, Eun Ja; Kim, Ji Chang; Kim, Jong Chul; And Others

    2000-01-01

    To evaluate, using magnetic resonance (MR) imaging, the clinal significance of the corpus callosum by measuring the size of various portions of the corpus callosum in children with cerebral palsy, and in paired controls. Fifty-two children (30 boys and 22 girls aged between six and 96 (median, 19) months) in whom cerebral palsy was clinically diagnosed underwent MR imaging. There were 23 term patients and 29 preterm, and the control group was selected by age and sex matching. Clinal subtypes of cerebral palsy were classified as hemiplegia (n=14), spastic diplegia (n=22), or spastic quadriplegia (n=16), and according to the severity of motor palsy, the condition was also classified as mild (n=26), moderate (n=13), or severe (n=13). In addition to the length and height of the corpus callosum, the thickness of its genu, body, transitional zone and splenium, as seen on midsagittal T1-weighted MR images, were also measured. Differences in the measured values of the two groups were statistically analysed and differences in the size of the corpus callosum according to the clinical severity and subtypes of cerebral palsy, and gestational age, were also assessed. Except for height, the measured values of the corpus callosum in patients with cerebral palsy were significantly less than those of the control group (p less than 0.05). Its size decreased according to the severity of motor palsy. Compared with term patients, the corpus callosum in preterm patients was considerably smaller (p less than 0.05). There was statistically significant correlation between the severity of motor palsy and the size of the corpus callosum. Quantitative evaluation of the corpus callosum might be a good indicator of neurologic prognosis, and a sensitive marker for assessing the extent of brain injury

  8. Clinical significance of the corpus callosum in cerebral palsy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Ja; Kim, Ji Chang [The Catholic University of Korea, Seoul (Korea, Republic of); Kim, Jong Chul [School of Medicine, Chungnam National University, Taejon (Korea, Republic of); And Others

    2000-10-01

    To evaluate, using magnetic resonance (MR) imaging, the clinal significance of the corpus callosum by measuring the size of various portions of the corpus callosum in children with cerebral palsy, and in paired controls. Fifty-two children (30 boys and 22 girls aged between six and 96 (median, 19) months) in whom cerebral palsy was clinically diagnosed underwent MR imaging. There were 23 term patients and 29 preterm, and the control group was selected by age and sex matching. Clinal subtypes of cerebral palsy were classified as hemiplegia (n=14), spastic diplegia (n=22), or spastic quadriplegia (n=16), and according to the severity of motor palsy, the condition was also classified as mild (n=26), moderate (n=13), or severe (n=13). In addition to the length and height of the corpus callosum, the thickness of its genu, body, transitional zone and splenium, as seen on midsagittal T1-weighted MR images, were also measured. Differences in the measured values of the two groups were statistically analysed and differences in the size of the corpus callosum according to the clinical severity and subtypes of cerebral palsy, and gestational age, were also assessed. Except for height, the measured values of the corpus callosum in patients with cerebral palsy were significantly less than those of the control group (p less than 0.05). Its size decreased according to the severity of motor palsy. Compared with term patients, the corpus callosum in preterm patients was considerably smaller (p less than 0.05). There was statistically significant correlation between the severity of motor palsy and the size of the corpus callosum. Quantitative evaluation of the corpus callosum might be a good indicator of neurologic prognosis, and a sensitive marker for assessing the extent of brain injury.

  9. Compiling a corpus-based dictionary grammar: an example for ...

    African Journals Online (AJOL)

    In this article it is shown how a corpus-based dictionary grammar may be compiled — that is, a mini-grammar fully based on corpus data and specifically written for use in and inte-grated with a dictionary. Such an effort is, to the best of our knowledge, a world's first. We exem-plify our approach for a Northern Sotho ...

  10. The Corpus of English as Lingua Franca in Academic Settings.

    Science.gov (United States)

    Mauranen, Anna

    2003-01-01

    Describes a project to make a corpus of English spoken as a lingua franca in university settings in Finland. This corpus is one of the first to address the need for corpora that show the target for English-as-a-Foreign-Language learners whose goal is not to speak with native speakers but to interact in communities where English is a lingua franca.…

  11. Acute aortic dissection type A discloses Corpus alienum

    Directory of Open Access Journals (Sweden)

    Kolat Philipp

    2009-01-01

    Full Text Available Abstract We report an unusual case of an aortic type A dissection with a corpus alienum which compresses the right ventricle. The patient successfully underwent an aortic root replacement in deep hypothermia with re-implantation of the coronary arteries using a modified Bentall procedure and the resection of the corpus alienum. Intraoperative finding reveals 3 greatly adhered gauze compresses, which were most likely forgotten in the operation 34 years ago.

  12. Experimental Polish-Lithuanian Corpus with the Semantic Annotation Elements

    Directory of Open Access Journals (Sweden)

    Danuta Roszko

    2015-06-01

    Full Text Available Experimental Polish-Lithuanian Corpus with the Semantic Annotation Elements In the article the authors present the experimental Polish-Lithuanian corpus (ECorpPL-LT formed for the idea of Polish-Lithuanian theoretical contrastive studies, a Polish-Lithuanian electronic dictionary, and as help for a sworn translator. The semantic annotation being brought into ECorpPL-LT is extremely useful in Polish-Lithuanian contrastive studies, and also proves helpful in translation work.

  13. A corpus and a concordancer of academic journal articles

    Directory of Open Access Journals (Sweden)

    Deny A. Kwary

    2018-02-01

    Full Text Available This data article presents a corpus (i.e. a selection of a big number of words in an electronic form and a concordancer (i.e. a tool to show the word in its context of use of academic journal articles. As the title suggests, the data were collected from research articles published in academic journals. The corpus contains 5,686,428 words selected from 895 journal articles published by Elsevier in 2011–2015. The corpus is classified into four subject areas: Health sciences, Life sciences, Physical Sciences, and Social Sciences, following the classifications of Scopus, which is the largest abstract and citation database of peer-reviewed scientific journals, books and conference proceedings. To ease the access and utilization of the corpus, a program to produce the key word in context (KWIC and word frequency was created and placed on the website: corpus.kwary.net. The corpus is a valuable resource for researchers, teachers, and translators working on academic English.

  14. Hemoperitoneum from corpus luteum rupture in patients with aplastic anemia.

    Science.gov (United States)

    Wang, Huaquan; Guo, Lifang; Shao, Zonghong

    2015-01-01

    Aplastic anemia is a rare hematopoietic stem-cell disorder that results in pancytopenia and hypocellular bone marrow. Women with aplastic anemia usually are at increased risk of corpus luteum rupture due to thrombocytopenia and infection. Here we report two cases had hemoperitoneum from corpus luteum rupture in patients with aplastic anemia in our center. Case 1 involved two episodes of hemoperitoneum resulting from rupture of the corpus luteum in a 23-year-old unmarried female with severe aplastic anemia. This patient was managed conservatively with platelet and packed red cell transfusion. Case 2 involved two episodes of hemoperitoneum resulting from rupture of the corpus luteum in a 33-year-old married patient with aplastic anemia. Emergency laparoscopy revealed massive hemoperitoneum. Bilateral salpingo-oophorectomy were performed successively with platelet and packed red cell transfusion. Hemoperitoneum resulting from a ruptured corpus luteum is a life-threatening condition in patients with aplastic anemia. Prompt and appropriate evaluation of corpus luteum rupture and emergent therapy are needed.

  15. A corpus and a concordancer of academic journal articles.

    Science.gov (United States)

    Kwary, Deny A

    2018-02-01

    This data article presents a corpus (i.e. a selection of a big number of words in an electronic form) and a concordancer (i.e. a tool to show the word in its context of use) of academic journal articles. As the title suggests, the data were collected from research articles published in academic journals. The corpus contains 5,686,428 words selected from 895 journal articles published by Elsevier in 2011-2015. The corpus is classified into four subject areas: Health sciences, Life sciences, Physical Sciences, and Social Sciences, following the classifications of Scopus, which is the largest abstract and citation database of peer-reviewed scientific journals, books and conference proceedings. To ease the access and utilization of the corpus, a program to produce the key word in context (KWIC) and word frequency was created and placed on the website: corpus.kwary.net. The corpus is a valuable resource for researchers, teachers, and translators working on academic English.

  16. Corpus Based Authenicity Analysis of Language Teaching Course Books

    Directory of Open Access Journals (Sweden)

    Emrah PEKSOY

    2017-12-01

    Full Text Available In this study, the resemblance of the language learning course books used in Turkey to authentic language spoken by native speakers is explored by using a corpus-based approach. For this, the 10-million-word spoken part of the British National Corpus was selected as reference corpus. After that, all language learning course books used in high schools in Turkey were scanned and transferred to SketchEngine, an online corpus query tool. Lastly, certain grammar points were extracted first from British National Corpus and then from course books; similaritites and differences were compared. At the end of the study, it was found that the language learning course books have little similarity to authentic language in terms of certain grammatical items and frequency of their collocations. In this way, the points to be revised and changed were explored. In addition, this study emphasized the role of corpus approach as a material development and analysis tool; and tested the functionality of course books for writers and for Ministry of National Education.

  17. Measurement of normal corpus callosum with MRI in Korean adults and morphological change of corpus callosum by grade of hydrocephalus

    International Nuclear Information System (INIS)

    Song, Dong Hoon; Chang, Seung Kuk; Kim, Jong Deok; Eun, Tchoong Kie; Park, Dong Woo

    1995-01-01

    To measure the size of normal corpus callosum in each portion using objective and reproducible method with MRI and evaluation of morphological change of corpus callosum by grade of hydrocephalus. Midsagittal T1-weighted MR imaging of the corpus callosum was investigated in 41 volunteers of normal Korean adults and 19 patients with hydrocephalus. Corpus callosum was measured for the anteroposterior length(A), height(B), and the thickness of genu(C), body(D), splenium(E), and the narrowest portion of body(F). And the analysis of morphology and signal intensity of the corpus callosum were also evaluated. Hydrocephalus was graded as mild, moderate, and severe, and comparison of thickness with normal corpus callosum in each portion was done. The mean length and height were 72.3 mm, 28.6 mm in male, and 70.7 mm, 28.9 mm in female. And the mean dimension for C, D, E and F were 13.1 mm, 8 mm, 13.2 mm, 5.2 mm in male, and 12.8 mm, 7.5 mm, 12.3 mm, 5 mm in female. The morphology of normal corpus callosum was 'hook' shaped on midline sagittal T1-weighted image. Narrowing at posterior third portion of body were present on 30 cases(73.2%) and even in thickness of the body in 11 cases(26.8%). The signal intensity of the corpus callosum on midsagittal T1-weighted spin echo image of normal cases was homogeneous hyperintense as compared with cerebral gray matter. In hydrocephalus, A and B were increased and other portions were decreased in thickness. Genu and the narrowest portion of body showed significant difference of thickness according to the grade of hydrocephalus. The mean dimension of all portion of corpus callosum were larger in male than female except for callosal height but not significant statistically with the exception of splenium. Hydrocephalus lead to morphological change of the corpus callosum. Among the portion of corpus callosum, genu and the narrowest portion of the body were thought to be the most sensitive indicators of degree in hydrocephalus

  18. Notes on Compiling a Corpus- Based Dictionary

    Directory of Open Access Journals (Sweden)

    František Čermák

    2011-10-01

    Full Text Available

    ABSTRACT: On the basis of sample analysis of a Czech adjective, a definition based on the data drawn from the Czech National Corpus (cf. Čermák and Schmiedtová 2003 is gradually compiled and finally offered, pointing at the drawbacks of definitions found in traditional dictionaries. Steps undertaken here are then generalized and used, in an ordered sequence (similar to a work-flow ordering, as topics, briefly discussed in the second part to which lexicographers of monolingual dictionaries should pay attention. These are supplemented by additional remarks and caveats useful in the compilation of a dictionary. Thus, a brief survey of some of the major steps of dictionary compilation is presented here, supplemented by the original Czech data, analyzed in their raw, though semiotically classified form.

    OPSOMMING: Aantekeninge oor die samestelling van 'n korpusgebaseerde woordeboek. Op grond van 'n steekproefontleding van 'n Tsjeggiese adjektief, word 'n definisie gebaseer op data ontleen aan die Tsjeggiese Nasionale Korpus (cf. Čermák en Schmiedtová 2003 geleidelik saamgestel en uiteindelik aangebied wat wys op die gebreke van definisies aangetref in tradisionele woordeboeke. Stappe wat hier onderneem word, word dan veralgemeen en gebruik in 'n geordende reeks (soortgelyk aan 'n werkvloeiordening, as onderwerpe, kortliks bespreek in die tweede deel, waaraan leksikograwe van eentalige woordeboeke aandag behoort te gee. Hulle word aangevul deur bykomende opmerkings en waarskuwings wat nuttig is vir die samestelling van 'n woordeboek. Op dié manier word 'n kort oorsig van sommige van die hoofstappe van woordeboeksamestelling hier aangebied, aangevul deur die oorspronklike Tsjeggiese data, ontleed in hul onbewerkte, alhoewel semioties geklassifiseerde vorm.

    Sleutelwoorde: EENTALIGE WOORDEBOEKE, KORPUSLEKSIKOGRAFIE, SINTAGMATIEK EN PARADIGMATIEK IN WOORDEBOEKE, WOORDEBOEKINSKRYWING, SOORTE LEMMAS, PRAGMATIEK, BEHANDELING VAN

  19. Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX-343 and PhTX-12

    DEFF Research Database (Denmark)

    Strømgaard, K; Bjørnsdottir, I; Andersen, K

    2000-01-01

    ) of the enantiomers of PhTX-343 and PhTX-12. The methods were optimised with respect to chiral selector, buffer pH, and temperature around the capillary. Thus, rac-PhTX-343 was resolved using a separation buffer containing 30 mM heptakis-(2, 6-di-O-methyl)-beta-cyclodextrin in 50 mM 6-aminocarproic acid (pH 4. 0......) at 15 degrees C. rac-PhTX-12 was not resolvable in this system, but could be resolved using a separation buffer containing 10% w/v of dextrin 10, a linear maltodextrin, in 50 mM 6-aminocaproic acid (pH 4.0) at 15 degrees C. Using these methods, the optical purity of the synthetic enantiomers...

  20. Contrast radiographic study of venous drainage of the corpus cavernosum and the corpus spongiosum of the cat penis.

    Science.gov (United States)

    Amiri, Ali Akbar; Gilanpour, Hassan; Veshkini, Abbas

    2014-01-01

    The aim of this study was to determine the drainage routes of the corpus cvernosum penis and the corpus spongiosum penis in the cat using contrast cavernosography. Five male cats, 1.5-2.5 years old, weighing between 4.5 and 5.5 kg were investigated. The cats were anesthetized and the root and the proximal part of the penis were exposed by an incision on the perineum reaching the scrotum. Each cat was radiographed in lateral and dorsal recumbency before and during injection of contrast medium into the erectile bodies. The corpus spongiosum penis was injected at the bulb of the penis and the corpus cavernosum penis at the root. Injection of contrast media into the cavernous bodies showed that both the external and internal iliac veins drain the erectile bodies into the caudal vena cava. Drainage from the corpus spongiosum penis was from the bulb for the proximal part and from the glans for the distal part. The corpus cavernosum penis was drained only proximally, from the crura. There was a network of veins above the pelvic symphysis and the drainage of erectile bodies where through various routes into the internal and external iliac veins.

  1. 78 FR 55214 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Science.gov (United States)

    2013-09-10

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 100 [Docket No. USCG-2013-0723] Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX AGENCY: Coast Guard, DHS... Neches River in Orange, TX from 3 p.m. on September 20, 2013, through 6 p.m. on September 22, 2013. This...

  2. 77 FR 47519 - Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX

    Science.gov (United States)

    2012-08-09

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 100 [Docket No. USCG-2012-0656] Annual Marine Events in the Eighth Coast Guard District, Sabine River; Orange, TX AGENCY: Coast Guard, DHS... Regulations for the S.P.O.R.T. Power Boat Neches River in Orange, TX from 3 p.m. on September 21, 2012...

  3. Tx-Rx Isolation Exploiting Tunable Balanced-Unbalanced Antennas Architecture

    DEFF Research Database (Denmark)

    Tatomirescu, Alexandru; Alrabadi, Osama; Pedersen, Gert Frølund

    2012-01-01

    The duplex filter is probably still the most expensive component in mobile handsets for the significant Transmitter (Tx) — Receiver (Rx) isolation required. This paper suggests to relax or even replace the duplex filter by equipping the Tx and the Rx with two separate antennas. The two antennas a...

  4. 78 FR 31429 - Proposed Amendment of Class E Airspace; Mason, TX

    Science.gov (United States)

    2013-05-24

    ...-1141; Airspace Docket No. 12-ASW-12] Proposed Amendment of Class E Airspace; Mason, TX AGENCY: Federal... proposes to amend Class E airspace at Mason, TX. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Mason County Airport. The FAA is taking this...

  5. 75 FR 39149 - Establishment of Low Altitude Area Navigation Route (T-284); Houston, TX

    Science.gov (United States)

    2010-07-08

    ... (T-284); Houston, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule... area navigation (RNAV) route T-284 for the Houston, TX, terminal area, is being withdrawn. As a result of Houston Area Air Traffic System (HAATS) Project, Phase 3C, program actions, the route is pending...

  6. 75 FR 16336 - Establishment of Low Altitude Area Navigation Route (T-284); Houston, TX

    Science.gov (United States)

    2010-04-01

    ... (T-284); Houston, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes a low altitude area navigation (RNAV) route, designated T-284, in the Houston... navigable airspace in the Houston, TX, terminal area. DATES: Effective date 0901 UTC, July 29, 2010. The...

  7. 78 FR 33019 - Proposed Amendment of Class E Airspace; Commerce, TX

    Science.gov (United States)

    2013-06-03

    ...-0269; Airspace Docket No. 13-ASW-3] Proposed Amendment of Class E Airspace; Commerce, TX AGENCY... action proposes to amend Class E airspace at Commerce, TX. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Commerce Municipal Airport (AAF). The FAA...

  8. 75 FR 31463 - Comal County Regional Habitat Conservation Plan, Comal County, TX

    Science.gov (United States)

    2010-06-03

    ... Wildlife Service, 10711 Burnet Road, Suite 200, Austin, TX 78758 or 512-490-0057. SUPPLEMENTARY INFORMATION... prepare an EIS and hold public scoping meetings published in the Federal Register on October 16, 2008 (73..., Austin, TX 78758; or by phone at 512/490-0057; or by fax to 512/ 490-0974. A limited number of printed...

  9. Anatomical and micro-morphological analysis of the fruit and vegetative organs of Inula oculus-christi L. in the Pannonian part of Serbia

    Directory of Open Access Journals (Sweden)

    Karanović Dunja S.

    2016-01-01

    Full Text Available Inula oculus-christi L. is a perennial plant, 20-60 cm high, growing in south-east Europe, central and southern Russia and some parts of Asia. It belongs to Pontic-Pannonian floristic element. In Pannonian part of Serbia this species is extremely rare, with very few recently confirmed literature and herbarium data. According to the field data for the period from 2013 to 2015, only one population of this species was recorded in Pannonian part of Serbia, on the site of Rimski Šanac, which is threatened by anthropogenic activities. Furthermore, anatomical and micro-morphological features of I. oculus-christi have not been documented so far. Therefore, in order to get better knowledge of the biology this species, as well as on the basis of the abovementioned, its anatomical and micro-morphological characteristics were investigated. Cross sections of the leaf, stem, rhizome and fruit were obtained using cryotechnique procedure by Leica CM 1850 cryostat. Using a light microscopy, detailed descriptions of anatomical characteristics of the analysed organs were given. The scanning electron microscopy revealed specific qualitative features of leaf and fruit that characterize the species. Obtained data may be useful in determination of this species and represent the valuable contribution to its micro-morphological and anatomical differentiation from other congeneric and related species. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 173002

  10. Classification of acquired lesions of the corpus callosum with MRI

    Energy Technology Data Exchange (ETDEWEB)

    Friese, S.A.; Bitzer, M.; Voigt, K.; Kueker, W. [Tuebingen Univ. (Germany). Abt. fuer Neuroradiologie; Freudenstein, D. [Department of Neurosurgery, Eberhard-Karls-University Tuebingen (Germany)

    2000-11-01

    MRI has facilitated diagnostic assessment of the corpus callosum. Diagnostic classification of solitary or multiple lesions of the corpus callosum has not attracted much attention, although signal abnormalities are not uncommon. Our aim was to identify characteristic imaging features of lesions frequently encountered in practice. We reviewed the case histories of 59 patients with lesions shown on MRI. The nature of the lesions was based on clinical features and/or long term follow-up (ischaemic 20, Virchow-Robin spaces 3, diffuse axonal injury 7, multiple sclerosis 11, hydrocephalus 5, acute disseminated encephalomyelitis 5, Marchiafava-Bignami disease 4, lymphoma 2, glioblastoma hamartoma each 1). The location in the sagittal plane, the relationship to the borders of the corpus callosum and midline and the size were documented. The 20 ischaemic lesions were asymmetrical but adjacent to the midline; the latter was involved in new or large lesions. Diffuse axonal injury commonly resulted in large lesions, which tended to be asymmetrical; the midline and borders of the corpus callosum were always involved. Lesions in MS were small, at the lower border of the corpus callosum next to the septum pellucidum, and crossed the midline asymmetrically. Acute disseminated encephalomyelitis and the other perivenous inflammatory diseases caused relatively large, asymmetrical lesions. Hydrocephalus resulted in lesions of the upper part of the corpus callosum, and mostly in its posterior two thirds; they were found in the midline. Lesions in Marchiafava-Bignami disease were large, often symmetrically in the midline in the splenium and did not reach the edge of the corpus callosum. (orig.)

  11. Human metabolites of brevetoxin PbTx-2: Identification and confirmation of structure

    Science.gov (United States)

    Guo, Fujiang; An, Tianying; Rein, Kathleen S.

    2010-01-01

    Four metabolites were identified upon incubation of brevetoxin (PbTx-2) with human liver microsomes. Chemical transformation of PbTx-2 confirmed the structures of three known metabolites BTX-B5, PbTx-9 and 41, 43-dihydro-BTX-B5 and a previously unknown metabolite, 41, 43-dihydro-PbTx-2. These metabolites were also observed upon incubation of PbTx-2 with nine human recombinant cytochrome P450s (1A1, 1A2, 2C8, 2C9, 2C19, 2D6, 2E1, 3A4 and 3A5). Cytochrome P450 3A4 produced oxidized metabolites while other CYPs generated the reduced products. PMID:20600229

  12. Incorporating sustainability into TxDOT's transportation decision making : summary of work performed, methods used, and results achieved.

    Science.gov (United States)

    2011-02-01

    This report summarizes the work performed in Fiscal Year (FY) 2009 and 2010 under TxDOT : Implementation Project 5-5541-01 Regional Workshops on Sustainability Enhancement : Tool. TxDOT Research Project 0-5541, Developing Sustainable Tra...

  13. CX-100 and TX-100 blade field tests.

    Energy Technology Data Exchange (ETDEWEB)

    Holman, Adam (USDA-Agriculture Research Service, Bushland, TX); Jones, Perry L.; Zayas, Jose R.

    2005-12-01

    In support of the DOE Low Wind Speed Turbine (LWST) program two of the three Micon 65/13M wind turbines at the USDA Agricultural Research Service (ARS) center in Bushland, Texas will be used to test two sets of experimental blades, the CX-100 and TX-100. The blade aerodynamic and structural characterization, meteorological inflow and wind turbine structural response will be monitored with an array of 75 instruments: 33 to characterize the blades, 15 to characterize the inflow, and 27 to characterize the time-varying state of the turbine. For both tests, data will be sampled at a rate of 30 Hz using the ATLAS II (Accurate GPS Time-Linked Data Acquisition System) data acquisition system. The system features a time-synchronized continuous data stream and telemetered data from the turbine rotor. This paper documents the instruments and infrastructure that have been developed to monitor these blades, turbines and inflow.

  14. Exploring theoretical functions of corpus data in teaching translation

    Directory of Open Access Journals (Sweden)

    Éric Poirier

    2016-04-01

    Full Text Available http://dx.doi.org/10.5007/2175-7968.2016v36nesp1p177 As language referential data banks, corpora are instrumental in the exploration of translation solutions in bilingual parallel texts or conventional usages of source or target language in monolingual general or specialized texts. These roles are firmly rooted in translation processes, from analysis and interpretation of source text to searching for an acceptable equivalent and integrating it into the production of the target text. Provided the creative and not the conservative way be taken, validation or adaptation of target text in accordance with conventional usages in the target language also benefits from corpora. Translation teaching is not exploiting this way of translating that is common practice in the professional translation markets around the world. Instead of showing what corpus tools can do to translation teaching, we start our analysis with a common issue within translation teaching and show how corpus data can help to resolve it in learning activities in translation courses. We suggest a corpus-driven model for the interpretation of ‘business’ as a term and as an item in complex terms based on source text pattern analysis. This methodology will make it possible for teachers to explain and justify interpretation rules that have been defined theoretically from corpus data. It will also help teachers to conceive and non-subjectively assess practical activities designed for learners of translation. Corpus data selected for the examples of rule-based interpretations provided in this paper have been compiled in a corpus-driven study (Poirier, 2015 on the translation of the noun ‘business’ in the field of specialized translation in business, economics, and finance from English to French. The corpus methodology and rule-based interpretation of senses can be generalized and applied in the definition of interpretation rules for other language pairs and other specialized simple and

  15. Exploring theoretical functions of corpus data in teaching translation

    Directory of Open Access Journals (Sweden)

    Éric Poirier

    2016-06-01

    Full Text Available As language referential data banks, corpora are instrumental in the exploration of translation solutions in bilingual parallel texts or conventional usages of source or target language in monolingual general or specialized texts. These roles are firmly rooted in translation processes, from analysis and interpretation of source text to searching for an acceptable equivalent and integrating it into the production of the target text. Provided the creative and not the conservative way be taken, validation or adaptation of target text in accordance with conventional usages in the target language also benefits from corpora. Translation teaching is not exploiting this way of translating that is common practice in the professional translation markets around the world. Instead of showing what corpus tools can do to translation teaching, we start our analysis with a common issue within translation teaching and show how corpus data can help to resolve it in learning activities in translation courses. We suggest a corpus-driven model for the interpretation of ‘business’ as a term and as an item in complex terms based on source text pattern analysis. This methodology will make it possible for teachers to explain and justify interpretation rules that have been defined theoretically from corpus data. It will also help teachers to conceive and non-subjectively assess practical activities designed for learners of translation. Corpus data selected for the examples of rule-based interpretations provided in this paper have been compiled in a corpus-driven study (Poirier, 2015 on the translation of the noun ‘business’ in the field of specialized translation in business, economics, and finance from English to French. The corpus methodology and rule-based interpretation of senses can be generalized and applied in the definition of interpretation rules for other language pairs and other specialized simple and complex terms. These works will encourage the

  16. MR imaging of spastic diplegia. The importance of corpus callosum

    International Nuclear Information System (INIS)

    Hayakawa, K.; Kanda, T.; Hashimoto, K.; Okuno, Y.; Yamori, Y.; Yuge, M.; Ando, R.; Ozaki, N.; Tamamoto, A.

    1996-01-01

    Purpose: The MR findings in patients with spastic diplegia were investigated and the role of MR imaging in assessing the extent of brain injury was evaluated. Material and Methods: 39 male and 24 female patients (preterm/term 43/20) were imaged using a 0.5 T MR system. Results: The MR findings in term patients were quite different from those in preterm patients; 55% of the term patients showed normal and minimal changes on MR, whereas 90.7% of the 43 preterm children had periventricular leucomalacia. The deep cerebral white matter was the most frequently involved site. Objective measurements revealed significant reductions of the entire sagittal area of corpus callosum in diplegic patients in comparison with normal controls. The motor plasy severity correlated well with the extent of corpus callosum involvement. Conclusion: The corpus callosum appears to be a sensitive marker site for the assessment of the extent of white matter injury. (orig.)

  17. Normal Corpus Callosum Dimensions Measured by MRI

    International Nuclear Information System (INIS)

    Kim, Ham Gyum

    2008-01-01

    As a result of measuring the size of corpus callosum in normal Korean people by using MRI, the following conclusions were obtained. 1. Maximum, minimum, and mean values by the region in whole subjects 1) Anteroposterior length amounted to the mean with 69.30 mm, the minimum with 50.70 mm, and the maximum with 80.40 mm. 2) Diameter of genu amounted to the mean with 11.93 mm, the minimum with 6.00 mm, and the maximum with 18.50 mm. 3) Diameter of mid body amounted to the mean with 7.00 mm, the minimum with 3.40 mm, and the maximum with 10.40 mm. 4) Diameter of narrowing portion amounted to the mean with 4.51 mm, the minimum with 0.80 mm, and the maximum with 9.50 mm. 5) Diameter of splenium amounted to the mean with 12.17 mm, the minimum with 6.90 mm, and the maximum with 17.20 mm. 2. Comparison by region according to the gender in the whole subjects 1) Anteroposterior length was bigger in men than in women, and showed the significant difference depending on gender. 2) Diameter of genu, diameter of mid body, and diameter of narrowing portion were bigger in men than in women, but there was no significant difference. 3) Diameter of splenium was bigger in men than in women, and showed the statistically significant difference. 3. Comparison by region according to the age in the whole subjects 1) Anteroposterior length was the biggest in the 50s at the age, and was smaller in heir 10s than other age levels. In addition, the significant difference was indicated depending on age. 2) Diameter of genu and diameter of mid body were the biggest in their 30s, and were smaller in the 60s than other age levels. And, the statistically significant difference was indicated. 3) Diameter of narrowing portion was the thickest in their 20s, and was thinner in their 60s than other age levels. And, the significant difference was indicated depending on age. 4) Diameter of splenium was the thickest in their 30s, and was thinner in their 10s than other age levels. And, the statistically

  18. Diffusion tensor analysis of corpus callosum in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Shoichi; Makino, Takahiro; Shirai, Wakako; Hattori, Takamichi [Department of Neurology, Graduate School of Medicine, Chiba University (Japan)

    2008-11-15

    Progressive supranuclear palsy (PSP) is a neurodegenerative disease featuring parkinsonism, supranuclear ophthalmoplegia, dysphagia, and frontal lobe dysfunction. The corpus callosum which consists of many commissure fibers probably reflects cerebral cortical function. Several previous reports showed atrophy or diffusion abnormalities of anterior corpus callosum in PSP patients, but partitioning method used in these studies was based on data obtained in nonhuman primates. In this study, we performed a diffusion tensor analysis using a new partitioning method for the human corpus callosum. Seven consecutive patients with PSP were compared with 29 age-matched patients with Parkinson's Disease (PD) and 19 age-matched healthy control subjects. All subjects underwent diffusion tensor magnetic resonance imaging, and the corpus callosum was partitioned into five areas on the mid-sagittal plane according to a recently established topography of human corpus callosum (CC1-prefrontal area, CC2-premotor and supplementary motor area, CC3-motor area, CC4-sensory area, CC5-parietal, temporal, and occipital area). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured in each area and differences between groups were analyzed. In the PSP group, FA values were significantly decreased in CC1 and CC2, and ADC values were significantly increased in CC1 and CC2. Receiver operating characteristic analysis showed excellent reliability of FA and ADC analyses of CC1 for differentiating PSP from PD. The anterior corpus callosum corresponding to the prefrontal, premotor, and supplementary motor cortices is affected in PSP patients. This analysis can be an additional test for further confirmation of the diagnosis of PSP.

  19. Diffusion tensor analysis of corpus callosum in progressive supranuclear palsy

    International Nuclear Information System (INIS)

    Ito, Shoichi; Makino, Takahiro; Shirai, Wakako; Hattori, Takamichi

    2008-01-01

    Progressive supranuclear palsy (PSP) is a neurodegenerative disease featuring parkinsonism, supranuclear ophthalmoplegia, dysphagia, and frontal lobe dysfunction. The corpus callosum which consists of many commissure fibers probably reflects cerebral cortical function. Several previous reports showed atrophy or diffusion abnormalities of anterior corpus callosum in PSP patients, but partitioning method used in these studies was based on data obtained in nonhuman primates. In this study, we performed a diffusion tensor analysis using a new partitioning method for the human corpus callosum. Seven consecutive patients with PSP were compared with 29 age-matched patients with Parkinson's Disease (PD) and 19 age-matched healthy control subjects. All subjects underwent diffusion tensor magnetic resonance imaging, and the corpus callosum was partitioned into five areas on the mid-sagittal plane according to a recently established topography of human corpus callosum (CC1-prefrontal area, CC2-premotor and supplementary motor area, CC3-motor area, CC4-sensory area, CC5-parietal, temporal, and occipital area). Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured in each area and differences between groups were analyzed. In the PSP group, FA values were significantly decreased in CC1 and CC2, and ADC values were significantly increased in CC1 and CC2. Receiver operating characteristic analysis showed excellent reliability of FA and ADC analyses of CC1 for differentiating PSP from PD. The anterior corpus callosum corresponding to the prefrontal, premotor, and supplementary motor cortices is affected in PSP patients. This analysis can be an additional test for further confirmation of the diagnosis of PSP

  20. Polyethylene glycol restores axonal conduction after corpus callosum transection

    Directory of Open Access Journals (Sweden)

    Ravinder Bamba

    2017-01-01

    Full Text Available Polyethylene glycol (PEG has been shown to restore axonal continuity after peripheral nerve transection in animal models. We hypothesized that PEG can also restore axonal continuity in the central nervous system. In this current experiment, coronal sectioning of the brains of Sprague-Dawley rats was performed after animal sacrifice. 3Brain high-resolution microelectrode arrays (MEA were used to measure mean firing rate (MFR and peak amplitude across the corpus callosum of the ex-vivo brain slices. The corpus callosum was subsequently transected and repeated measurements were performed. The cut ends of the corpus callosum were still apposite at this time. A PEG solution was applied to the injury site and repeated measurements were performed. MEA measurements showed that PEG was capable of restoring electrophysiology signaling after transection of central nerves. Before injury, the average MFRs at the ipsilateral, midline, and contralateral corpus callosum were 0.76, 0.66, and 0.65 spikes/second, respectively, and the average peak amplitudes were 69.79, 58.68, and 49.60 μV, respectively. After injury, the average MFRs were 0.71, 0.14, and 0.25 spikes/second, respectively and peak amplitudes were 52.11, 8.98, and 16.09 μV, respectively. After application of PEG, there were spikes in MFR and peak amplitude at the injury site and contralaterally. The average MFRs were 0.75, 0.55, and 0.47 spikes/second at the ipsilateral, midline, and contralateral corpus callosum, respectively and peak amplitudes were 59.44, 45.33, 40.02 μV, respectively. There were statistically differences in the average MFRs and peak amplitudes between the midline and non-midline corpus callosum groups (P < 0.01, P < 0.05. These findings suggest that PEG restores axonal conduction between severed central nerves, potentially representing axonal fusion.

  1. Polyethylene glycol restores axonal conduction after corpus callosum transection.

    Science.gov (United States)

    Bamba, Ravinder; Riley, D Colton; Boyer, Richard B; Pollins, Alonda C; Shack, R Bruce; Thayer, Wesley P

    2017-05-01

    Polyethylene glycol (PEG) has been shown to restore axonal continuity after peripheral nerve transection in animal models. We hypothesized that PEG can also restore axonal continuity in the central nervous system. In this current experiment, coronal sectioning of the brains of Sprague-Dawley rats was performed after animal sacrifice. 3Brain high-resolution microelectrode arrays (MEA) were used to measure mean firing rate (MFR) and peak amplitude across the corpus callosum of the ex-vivo brain slices. The corpus callosum was subsequently transected and repeated measurements were performed. The cut ends of the corpus callosum were still apposite at this time. A PEG solution was applied to the injury site and repeated measurements were performed. MEA measurements showed that PEG was capable of restoring electrophysiology signaling after transection of central nerves. Before injury, the average MFRs at the ipsilateral, midline, and contralateral corpus callosum were 0.76, 0.66, and 0.65 spikes/second, respectively, and the average peak amplitudes were 69.79, 58.68, and 49.60 μV, respectively. After injury, the average MFRs were 0.71, 0.14, and 0.25 spikes/second, respectively and peak amplitudes were 52.11, 8.98, and 16.09 μV, respectively. After application of PEG, there were spikes in MFR and peak amplitude at the injury site and contralaterally. The average MFRs were 0.75, 0.55, and 0.47 spikes/second at the ipsilateral, midline, and contralateral corpus callosum, respectively and peak amplitudes were 59.44, 45.33, 40.02 μV, respectively. There were statistically differences in the average MFRs and peak amplitudes between the midline and non-midline corpus callosum groups ( P < 0.01, P < 0.05). These findings suggest that PEG restores axonal conduction between severed central nerves, potentially representing axonal fusion.

  2. Tx2-6 toxin of the Phoneutria nigriventer spider potentiates rat erectile function☆

    Science.gov (United States)

    Nunes, K.P.; Costa-Gonçalves, A.; Lanza, L.F.; Cortes, S.F.; Cordeiro, M.N.; Richardson, M.; Pimenta, A.M.C.; Webb, R.C.; Leite, R.; De Lima, M.E.

    2011-01-01

    The venom of the spider Phoneutria nigriventer contains several toxins that have bioactivity in mammals and insects. Accidents involving humans are characterized by various symptoms including penile erection. Here we investigated the action of Tx2-6, a toxin purified from the P. nigriventer spider venom that causes priapism in rats and mice. Erectile function was evaluated through changes in intracavernosal pressure/mean arterial pressure ratio (ICP/MAP) during electrical stimulation of the major pelvic ganglion (MPG) of normotensive and deoxycorticosterone-acetate (DOCA)-salt hypertensive rats. Nitric oxide (NO) release was detected in cavernosum slices with fluorescent dye (DAF-FM) and confocal microscopy. The effect of Tx2-6 was also characterized after intracavernosal injection of a non-selective nitric oxide synthase (NOS) inhibitor, L-NAME. Subcutaneous or intravenous injection of Tx2-6 potentiated the elevation of ICP/MAP induced by ganglionic stimulation. L-NAME inhibited penile erection and treatment with Tx2-6 was unable to reverse this inhibition. Tx2-6 treatment induced a significant increase of NO release in cavernosum tissue. Attenuated erectile function of DOCA-salt hypertensive rats was fully restored after toxin injection. Tx2-6 enhanced erectile function in normotensive and DOCA-salt hypertensive rats, via the NO pathway. Our studies suggest that Tx2-6 could be important for development of new pharmacological agents for treatment of erectile dysfunction. PMID:18397797

  3. Synthesis and Electrochemical Properties of Two-Dimensional RGO/Ti3C2Tx Nanocomposites

    Directory of Open Access Journals (Sweden)

    Changjie Shen

    2018-01-01

    Full Text Available MXene is a new type of two-dimensional layered material. Herein, a GO/Ti3C2Tx nanocomposite was prepared by a simple liquid phase method, and the obtained GO/Ti3C2Tx was transformed into RGO/Ti3C2Tx under high temperature with Ar/H2. The prepared samples were characterized using X-ray diffraction (XRD, Raman measurement, scanning electron microscopy (SEM, energy disperse spectroscopy (EDS, and X-ray photoelectron spectroscopy (XPS. As an electrode material in lithium-ion batteries, the RGO/Ti3C2Tx nanocomposite exhibited an excellent electrochemical performance and an excellent rate performance. Compared to pure Ti3C2Tx, the nanocomposite had a better reversible capacity at different current densities and had no attenuation after 200 cycles, which is one time higher than pure Ti3C2Tx. The improvement in the specific capacity was due to the excellent electrical conductivity and the unique structure of RGO, in which a charge transfer bridge was built among the Ti3C2Tx flakes. Such a bridge shortened the transmission distance of the electrons and ions and effectively controlled the restacking of the laminated materials.

  4. The Shona Corpus and the Problem of Tagging?

    Directory of Open Access Journals (Sweden)

    Emmanuel Chabata

    2011-10-01

    Full Text Available

    Abstract: In this paper the writer examines problems the African Languages Lexical (ALLEX Project (at present the African Languages Research Institute (ALRI? encountered while tagging the Shona corpus. The problems to be highlighted include general problems which apply to more than one language as well as problems peculiar to Shona. The paper was inspired by the challenges the writer encountered when he took part in building the Shona corpus. An analysis of the problems that most corpus builders face shows that more problems are likely to be encountered when dealing with spoken corpora than with written corpora. The paper demonstrates that tagging is an important component of corpus building as it makes it easier for a researcher to extract relevant data. To utilise the benefits of a tagged corpus, the tagging should be thorough and accurate. Wellinformed decisions form an integral part of the tagging process since the utility of a tagged corpus depends largely on the input of the tagging process. This paper shows the need to take the tagging process seriously.

    Keywords: ALLEX PROJECT, COMPUTER, CORPUS, ENCODING, FOREIGN WORD, LEMMATIZATION, LEXICOGRAPHY, MONITOR CORPUS, PART OF SPEECH, SCANNING, SHONA, SLANG, TAGGING, TRANSCRIPTION, WORD

    Opsomming: Die Shonakorpus en die probleem van etikettering, In hierdieartikel ondersoek die outeur probleme wat die African Languages Lexical (ALLEX Project (tansdie African Languages Research Institute (ALRI» teegekom het terwyl die Shonakorpus geetiketteeris. Die probleme wat bespreek word, sluit algemene probleme in wat van toepassing is opmeer as een taa, sowel as spesifieke probleme wat eie aan Shona is. Die artikel het sy ontstaan indie uitdagings wat die outeur teegekom het terwyl hy deel gehad het aan die opbou van die Shonakorpus.'n Ontieding van die probleme waarvoor die meeste korpusbouers te staan kom, toon datdaar waarskynlik meer probleme teegekom word wanneer daar met gesproke

  5. Partial segmental thrombosis of the corpus cavernosum: imaging findings.

    Science.gov (United States)

    Moya-Sánchez, E; Medina-Benítez, A; Medina-Salas, V; Fernández-Navarro, L

    2018-03-05

    Partial segmental thrombosis of the corpus cavernosum is an unusual clinical condition of unknown origin that mainly affects young males, whose characteristic presentation is the appearance of unexplained perineal pain associated with a palpable perineal mass. This entity consists of thrombosis in the perineal portion of the corpus cavernosum, usually unilateral and it is associated with underlying malignant pathologies and predisposing factors such as microtrauma. After the adequate adherence to conservative treatment, the appearance of complications such as erectile dysfunction is very uncommon. Copyright © 2018 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Corpus Juris ja Eesti : [bakalaureusetöö] / Artur Kink ; Tartu Ülikool, õigusteaduskond ; juhendaja: Eerik Kergandberg

    Index Scriptorium Estoniae

    Kink, Artur

    1999-01-01

    Corpus Jurise taust ja areng - finantshuvide kaitse areng, Corpus Jurise ajalugu; Corpus Jurise õiguslik baas (Amsterdami leping), ülesehitus ja struktuur (üleeuroopalise territoriaalsuse printsiip, kohtuliku kontrolli printsiip, "vastuväitelise" protsessi printsiip, kohaliku õiguse subsidiaarsuse printsiip)

  7. Walter Max Dale (formerly Deutsch) (1894-1969): pioneer and eminent radiobiochemist at the Christie Hospital and Holt Radium Institute, Manchester.

    Science.gov (United States)

    Shreeve, David R

    2010-05-01

    The political upheaval in Germany in 1933 and subsequent movement of medical scholars with the support of the Rockefeller Foundation allowed Manchester to benefit from the arrival of Dr Walter Deutsch, later known as Dr Walter Dale. His research background enabled him to develop a radiobiochemistry laboratory at the Christie Hospital and Holt Radium Institute where he became a world authority on the effects of X-rays on enzymes and also the protective effect of additional solutes. In 1959 he initiated and then edited the International Journal of Radiation Biology. By the time of his retirement in 1962 the strength of his research resulted in his laboratory being recognized by the Medical Research Council.

  8. Antifungal activity of nettle (Urtica dioica L.), colocynth (Citrullus colocynthis L. Schrad), oleander (Nerium oleander L.) and konar (Ziziphus spina-christi L.) extracts on plants pathogenic fungi.

    Science.gov (United States)

    Hadizadeh, I; Peivastegan, B; Kolahi, M

    2009-01-01

    Anti-mycotic activity of the ethanol extracts from Nettle (Urtica dioica L.), Colocynth (Citrullus colocynthis L. Schrad), Konar (Ziziphus spina-christi L.) and Oleander (Nerium oleander L.) floral parts were screened in vitro against four important plant pathogenic fungi viz.; Alternaria alternate, Fusarium oxysporum, Fusarium solani and Rizoctonia solani using agar dilution bioassay. Extracts showed antifungal activity against all the tested fungi. Among the plants, Nettle and Colocynth were the most effective against A. alternate and R. solani while Oleander possesses the best inhibition on F. oxysporum and F. solani. Konar was the most effective extract by reducing the growth of Rizoctonia solani than other fungi. These results showed that extracts could be considered suitable alternatives to chemical additives for the control of fungal diseases in plants.

  9. Designing a Lexical Database for a Combined Use of Corpus Annotation and Dictionary Editing

    DEFF Research Database (Denmark)

    Kristoffersen, Jette Hedegaard; Troelsgård, Thomas; Langer, Gabriele

    2016-01-01

    In a combined corpus-dictionary project, you would need one lexical database that could serve as a shared “backbone” for both corpus annotation and dictionary editing, but it is not that easy to define a database structure that applies satisfactorily to both these purposes. In this paper, we...... will exemplify the problem and present ideas on how to model structures in a lexical database that facilitate corpus annotation as well as dictionary editing. The paper is a joint work between the DGS Corpus Project and the DTS Dictionary Project. The two projects come from opposite sides of the spectrum (one...... adjusting a lexical database grown from dictionary making for corpus annotating, one building a lexical database in parallel with corpus annotation and editing a corpus-based dictionary), and we will consider requirements and feasible structures for a database that can serve both corpus and dictionary....

  10. A corpus of images and text in online news

    NARCIS (Netherlands)

    L. Hollink (Laura); A. Bedjeti (Adriatik); M. van Harmelen; D. Elliott (Desmond)

    2016-01-01

    htmlabstractIn recent years, several datasets have been released that include images and text, giving impulse to new methods that combine natural language processing and computer vision. However, there is a need for datasets of images in their natural textual context. The ION corpus contains 300K

  11. The Use of Corpus Examples for Language Comprehension and Production

    Science.gov (United States)

    Frankenberg-Garcia, Ana

    2014-01-01

    One of the many new features of English language learners' dictionaries derived from the technological developments that have taken place over recent decades is the presence of corpus-based examples to illustrate the use of words in context. However, empirical studies have generally not been able to produce conclusive evidence about their…

  12. Open Corpus Adaptation++ in GALE : friend or foe?

    NARCIS (Netherlands)

    De Bra, P.M.E.; Smits, D.; Pechenizkiy, M.; Knutov, E.; Yudelson, M.; Abel, F.; Houben, G.J.P.M.; Herder, E.

    2012-01-01

    "Open" has quickly become the hottest topic in any field related to information, including open government data, open learning resources, open user models, … Open Corpus Adaptation has been defined as the ability to perform adaptation to resources located anywhere on the Web. This leaves the

  13. The Dependency Structure of Coordinate Phrases: A Corpus Approach

    Science.gov (United States)

    Temperley, David

    2005-01-01

    Hudson (1990) proposes that each conjunct in a coordinate phrase forms dependency relations with heads or dependents outside the coordinate phrase (the "multi-head" view). This proposal is tested through corpus analysis of Wall Street Journal text. For right-branching constituents (such as direct-object NPs), a short-long preference for conjunct…

  14. Enemy Combatant Detainees: Habeas Corpus Challenges in Federal Court

    Science.gov (United States)

    2006-09-26

    Separation of Powers Issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 Eliminating Federal Court Jurisdiction Where There Is No State Court Review . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 1 542 U.S. 466 (2004). Enemy Combatant Detainees: Habeas Corpus Challenges in Federal Court In Rasul v. Bush,1 a divided Supreme Court declared that “a state

  15. You Should Have the Body: Understanding Habeas Corpus

    Science.gov (United States)

    Landman, James

    2008-01-01

    English legal commentator William Blackstone described the writ of habeas corpus as a second Magna Carta, and Supreme Court Chief Justice John Marshall called it the "great writ." It has been part of the Anglo-American common law tradition since the Middle Ages. In the United States, it has been a source of tension between state and…

  16. Corpus callosum atrophy in patients with mild Alzheimer's disease

    DEFF Research Database (Denmark)

    Frederiksen, Kristian Steen; Garde, Ellen; Skimminge, Arnold

    2011-01-01

    Several studies have found atrophy of the corpus callosum (CC) in patients with Alzheimer's disease (AD). However, it remains unclear whether callosal atrophy is already present in the early stages of AD, and to what extent it may be associated with other structural changes in the brain......, such as age-related white matter changes (ARWMC) and progression of the disease....

  17. The NCHLT speech corpus of the South African languages

    CSIR Research Space (South Africa)

    Barnard, E

    2014-05-01

    Full Text Available The NCHLT speech corpus contains wide-band speech from approximately 200 speakers per language, in each of the eleven of cial languages of South Africa. We describe the design and development processes that were undertaken in order to develop...

  18. Interaction as 'involvement' in writing for students: a corpus linguistic ...

    African Journals Online (AJOL)

    Interaction as 'involvement' in writing for students: a corpus linguistic analysis of a key readability feature. E Hilton Hubbard. Abstract. The rapid change in the demographics of South Africa's tertiary level student population over the last decade — and most specifically the huge increase in those who have to study at a ...

  19. A Corpus-Based Comparative Study of "Learn" and "Acquire"

    Science.gov (United States)

    Yang, Bei

    2016-01-01

    As an important yet intricate linguistic feature in English language, synonymy poses a great challenge for second language learners. Using the 100 million-word British National Corpus (BNC) as data and the software Sketch Engine (SkE) as an analyzing tool, this article compares the usage of "learn" and "acquire" used in natural…

  20. Corpus-Based Rhythmic Pattern Analysis of Ragtime Syncopation

    NARCIS (Netherlands)

    Koops, Hendrik Vincent; Volk, A.; de Haas, W.B.

    2015-01-01

    This paper presents a corpus-based study on rhythmic patterns in the RAG-collection of approximately 11.000 symbolically encoded ragtime pieces. While characteristic musical features that define ragtime as a genre have been debated since its inception, musicologists argue that specific syncopation

  1. A new English–Arabic parallel text corpus for lexicographic ...

    African Journals Online (AJOL)

    The chosen source texts deal with a variety of topics such as the environment, globalization, psychology, history, politics, drama, etc. Their Arabic translations were taken from The World of Knowledge series published by the National Council for Culture, Arts and Letters (NCCAL) in Kuwait. Keywords: parallel corpus ...

  2. An annotated corpus with nanomedicine and pharmacokinetic parameters

    Directory of Open Access Journals (Sweden)

    Lewinski NA

    2017-10-01

    Full Text Available Nastassja A Lewinski,1 Ivan Jimenez,1 Bridget T McInnes2 1Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA, 2Department of Computer Science, Virginia Commonwealth University, Richmond, VA, USA Abstract: A vast amount of data on nanomedicines is being generated and published, and natural language processing (NLP approaches can automate the extraction of unstructured text-based data. Annotated corpora are a key resource for NLP and information extraction methods which employ machine learning. Although corpora are available for pharmaceuticals, resources for nanomedicines and nanotechnology are still limited. To foster nanotechnology text mining (NanoNLP efforts, we have constructed a corpus of annotated drug product inserts taken from the US Food and Drug Administration’s Drugs@FDA online database. In this work, we present the development of the Engineered Nanomedicine Database corpus to support the evaluation of nanomedicine entity extraction. The data were manually annotated for 21 entity mentions consisting of nanomedicine physicochemical characterization, exposure, and biologic response information of 41 Food and Drug Administration-approved nanomedicines. We evaluate the reliability of the manual annotations and demonstrate the use of the corpus by evaluating two state-of-the-art named entity extraction systems, OpenNLP and Stanford NER. The annotated corpus is available open source and, based on these results, guidelines and suggestions for future development of additional nanomedicine corpora are provided. Keywords: nanotechnology, informatics, natural language processing, text mining, corpora

  3. Using the Corpus of Spoken Afrikaans to generate an Afrikaans ...

    African Journals Online (AJOL)

    This paper presents two chatbot systems, ALICE and. Elizabeth, illustrating the dialogue knowledge representation and pattern matching techniques of each. We discuss the problems which arise when using the. Corpus of Spoken Afrikaans (Korpus Gesproke Afrikaans) to retrain the ALICE chatbot system with human ...

  4. Euphemism vs explicitness: A corpus-based analysis of translated ...

    African Journals Online (AJOL)

    This article examines the governing initial norms, namely explicitness and euphemism in English source texts and Ndebele translations, focusing on how these norms influenced the strategies chosen by the Ndebele translators in the translation of taboo terms. In the article, a corpus-based approach is used to identify head ...

  5. The Danish NOMCO Corpus Multimodal Interaction in First Acquaintance Conversations

    DEFF Research Database (Denmark)

    Paggio, Patrizia; Navarretta, Costanza

    2016-01-01

    , specifically head movements, facial expressions, and body posture. The corpus has served as the empirical basis for a number of studies of communication phenomena related to turn management, feedback exchange, information packaging and the expression of emotional attitudes. We describe the annotation scheme...

  6. Corpus Planning for the Southern Peruvian Quechua Language.

    Science.gov (United States)

    Coronel-Molina, Serafin M.

    1997-01-01

    The discussion of corpus planning for the Southern Quechua language variety of Peru examines issues of graphization, standardization, modernization, and renovation of Quechua in the face of increasing domination by the Spanish language. The efforts of three major groups of linguists and other scholars working on language planning in Peru, and the…

  7. Defining Formats and Corpus- based Examples in the General ...

    African Journals Online (AJOL)

    rbr

    Institute, University of Zimbabwe, Harare, Zimbabwe (langa@arts.uz.ac.zw). Abstract: In this article the writer ... sentative" in terms of size in order to be appropriately used as basis for such corpus-based diction- aries, the ISN editors .... (e) the format should suggest a preference rather than a restriction. For COBUILD, a good ...

  8. Learner features in a New Corpus-based Swahili dictionary ...

    African Journals Online (AJOL)

    As far as traditionally published Swahili language dictionaries are concerned, throughout the long history of Swahili lexicography, most new dictionaries were based on their predecessors. Thus far the only innovative traditionally printed corpus-based dictionary has been published by Finnish scholars (Abdulla et al. 2002).

  9. Considering bilingual dictionaries against a corpus. Do English ...

    African Journals Online (AJOL)

    This article investigates the extent to which four representatives of the latest generation of English-French / French-English dictionaries present "real English", i.e. actually used meanings of actually used English word patterns. The findings of a corpus study of the verb CONSIDER are confronted with the entries for this verb ...

  10. An annotated corpus with nanomedicine and pharmacokinetic parameters.

    Science.gov (United States)

    Lewinski, Nastassja A; Jimenez, Ivan; McInnes, Bridget T

    2017-01-01

    A vast amount of data on nanomedicines is being generated and published, and natural language processing (NLP) approaches can automate the extraction of unstructured text-based data. Annotated corpora are a key resource for NLP and information extraction methods which employ machine learning. Although corpora are available for pharmaceuticals, resources for nanomedicines and nanotechnology are still limited. To foster nanotechnology text mining (NanoNLP) efforts, we have constructed a corpus of annotated drug product inserts taken from the US Food and Drug Administration's Drugs@FDA online database. In this work, we present the development of the Engineered Nanomedicine Database corpus to support the evaluation of nanomedicine entity extraction. The data were manually annotated for 21 entity mentions consisting of nanomedicine physicochemical characterization, exposure, and biologic response information of 41 Food and Drug Administration-approved nanomedicines. We evaluate the reliability of the manual annotations and demonstrate the use of the corpus by evaluating two state-of-the-art named entity extraction systems, OpenNLP and Stanford NER. The annotated corpus is available open source and, based on these results, guidelines and suggestions for future development of additional nanomedicine corpora are provided.

  11. Corpus applications for the African languages, with special ...

    African Journals Online (AJOL)

    In order to illustrate the feasibility of corpus applications for the African languages at present, the article first considers 'fundamental linguistic research' in the fields of phonetics and question particles. It is shown how that research was boosted as a result of the utilisation of corpora. In a second section 'language teaching ...

  12. EuroGOV: Engineering a Multilingual Web Corpus

    NARCIS (Netherlands)

    Sigurbjörnsson, B.; Kamps, J.; de Rijke, M.

    2005-01-01

    EuroGOV is a multilingual web corpus that was created to serve as the document collection for WebCLEF, the CLEF 2005 web retrieval task. EuroGOV is a collection of web pages crawled from the European Union portal, European Union member state governmental web sites, and Russian government web sites.

  13. Parenting, corpus callosum, and executive function in preschool children.

    Science.gov (United States)

    Kok, Rianne; Lucassen, Nicole; Bakermans-Kranenburg, Marian J; van IJzendoorn, Marinus H; Ghassabian, Akhgar; Roza, Sabine J; Govaert, Paul; Jaddoe, Vincent W; Hofman, Albert; Verhulst, Frank C; Tiemeier, Henning

    2014-01-01

    In this longitudinal population-based study (N = 544), we investigated whether early parenting and corpus callosum length predict child executive function abilities at 4 years of age. The length of the corpus callosum in infancy was measured using postnatal cranial ultrasounds at 6 weeks of age. At 3 years, two aspects of parenting were observed: maternal sensitivity during a teaching task and maternal discipline style during a discipline task. Parents rated executive function problems at 4 years of age in five domains of inhibition, shifting, emotional control, working memory, and planning/organizing, using the Behavior Rating Inventory of Executive Function-Preschool Version. Maternal sensitivity predicted less executive function problems at preschool age. A significant interaction was found between corpus callosum length in infancy and maternal use of positive discipline to determine child inhibition problems: The association between a relatively shorter corpus callosum in infancy and child inhibition problems was reduced in children who experienced more positive discipline. Our results point to the buffering potential of positive parenting for children with biological vulnerability.

  14. Sexual dimorphism of the human corpus callosum: Digital morphometric study

    Directory of Open Access Journals (Sweden)

    Spasojević Goran

    2006-01-01

    Full Text Available Background/Aim. Changes in the morphology and the size of the corpus callosum, are related to various pathological conditions. An analysis of these changes requires data about sexual dimorphism of the corpus callosum, which we tried to obtain in our study. We also investigated the method of digital morphometry and compared the obtained results with the results of other authors obtained by magnetic resonance imaging or by planimetry. Methods. A morphological research included 34 human brains (cadavers of both sexes − 19 female and 15 male aged 26−72 years. By digital morphometry using an AutoCAD software we performed measurements in the corpus callosum: the length (L, width in the half of its length (WW’, length of its cortical margin (LCM, area and perimeter of the anterior and posterior callosal segments, as well as the area and perimeter of the corpus callosum section area. The investigated parameters were analyzed and compared between the females and males. Results. There was not a statistically significant difference between the males and females in the investigated parameters of the corpus callosum (t test; p > 0.05, including the mean values of the two most important parameters, the surface of its midsagittal section area (males 654.11 mm2; females 677.40 mm2 and of its perimeter (males 19.61 cm; females 19.72 cm. The results obtained by digital morphometry were in the range of the results of other authors obtained by magnetic resonance and by planimetry. However, the value of Pearson coefficient of linear correlation between the section surface area and perimeter of the corpus callosum in the males was highly significant (rxy = 0.6943, p < 0.01, while in the females this value was statistically insignificant. Conclusion. Digital morphometry is accurate method in encephalometric investigations. Our results suggest that the problem of sexual dimorphism of the corpus callosum is very complex, because the identical variables (section

  15. Backwater Flooding in San Marcos, TX from the Blanco River

    Science.gov (United States)

    Earl, Richard; Gaenzle, Kyle G.; Hollier, Andi B.

    2016-01-01

    Large sections of San Marcos, TX were flooded in Oct. 1998, May 2015, and Oct. 2015. Much of the flooding in Oct. 1998 and Oct. 2015 was produced by overbank flooding of San Marcos River and its tributaries by spills from upstream dams. The May 2015 flooding was almost entirely produced by backwater flooding from the Blanco River whose confluence is approximately 2.2 miles southeast of downtown. We use the stage height of the Blanco River to generate maps of the areas of San Marcos that are lower than the flood peaks and compare those results with data for the observed extent of flooding in San Marcos. Our preliminary results suggest that the flooding occurred at locations more than 20 feet lower than the maximum stage height of the Blanco River at San Marcos gage (08171350). This suggest that the datum for either gage 08171350 or 08170500 (San Marcos River at San Marcos) or both are incorrect. There are plans for the U.S. Army Corps of Engineers to construct a Blanco River bypass that will divert Blanco River floodwaters approximately 2 miles farther downstream, but the $60 million price makes its implementation problematic.

  16. Corpus callosum dysgenesis and lipoma: embryologic and magnetic resonance imaging aspects

    International Nuclear Information System (INIS)

    Abreu Junior, Luiz de; Borri, Maria Lucia; Wolosker, Angela Maria Borri; Hartmann, Luiz Guilherme de Carvalho; Galvao Filho, Mario de Melo; D'Ippolito, Giuseppe

    2005-01-01

    The corpus callosum is the major system of association fibers that permits communication of both cerebral hemispheres. Magnetic resonance imaging has improved the study of brain malformations, including the corpus callosum dysgenesis. Lipoma is a common finding in the spectrum of corpus callosum dysgenesis. The purpose of these study was to review the embryologic events and the magnetic resonance imaging aspects related to the corpus callosum dysgenesis and to the formation of the related lipoma. (author)

  17. EnviroAtlas - Austin, TX - Meter-Scale Urban Land Cover (MULC) Data (2010)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Austin, TX EnviroAtlas One Meter-scale Urban Land Cover (MULC) Data were generated from United States Department of Agriculture (USDA) National Agricultural...

  18. 78 FR 14909 - Amendment of Class B Airspace Description; Houston, TX

    Science.gov (United States)

    2013-03-08

    ...-0079; Airspace Docket No. 13-AWA-1] RIN 2120-AA66 Amendment of Class B Airspace Description; Houston.... SUMMARY: This action amends the description of the Houston, TX, Class B airspace area by changing the... 14910

  19. Software development to implement the TxDOT culvert rating guide.

    Science.gov (United States)

    2013-05-01

    This implementation project created CULVLR: Culvert Load Rating, Version 1.0.0, a Windows-based : desktop application software package that automates the process by which Texas Department of Transportation : (TxDOT) engineers and their consultants ...

  20. Incorporating sustainability into TxDOT's transportation decision-making : interactive workshop

    Science.gov (United States)

    2010-01-01

    The workshop is intended for new and experienced technical staff in TxDOT headquarters, district, and area offices to better understand how sustainability performance measures can be used at the sketch-planning level of project consideration. The wor...

  1. A K/Ka band radiating element for Tx/Rx phased array

    KAUST Repository

    Sandhu, Ali Imran; Arnieri, E.; Amendola, G.; Boccia, L.; Meniconi, E.; Ziegler, V.

    2017-01-01

    The paper presents a K/Ka band radiating element for TX/RX phased arrays. Dual band operations is obtained using a single radiating surface: a novel radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The array elements are optimized to scan the beam in excess of 50° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  2. T-x projections of phase diagrams of the MeF-BeF2 systems

    International Nuclear Information System (INIS)

    Korenev, Yu.M.; Rykov, A.N.; Novoselova, A.V.

    1976-01-01

    The T-x projections of the state diagrams of the systems MeF-BeF 2 (Me=Li-Rb) have been plotted. Transformation of P-x cross sections of the system state diagrams with decreasing temperature have been considered with the aid, of the general view of T-x projections. The nature of sublimation of the compounds formed in these systems is discussed

  3. A K/Ka band radiating element for Tx/Rx phased array

    KAUST Repository

    Sandhu, Ali Imran

    2017-01-20

    The paper presents a K/Ka band radiating element for TX/RX phased arrays. Dual band operations is obtained using a single radiating surface: a novel radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The array elements are optimized to scan the beam in excess of 50° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  4. Corpus-Based Research and Pedagogy in EAP: From Lexis to Genre

    Science.gov (United States)

    Flowerdew, Lynne

    2015-01-01

    This plenary paper showcases current corpus-based research on written academic English, illustrating the tight links that exist between corpus research and pedagogic applications. I first explicate Sinclair's concept of the "lexical approach", which underpins much corpus research and pedagogy. I then discuss studies which focus on…

  5. Using Google as a Super Corpus to Drive Written Language Learning: A Comparison with the British National Corpus

    Science.gov (United States)

    Sha, Guoquan

    2010-01-01

    Data-driven learning (DDL), or corpus-based language learning, involves the learner in an exploratory task to discover appropriate expressions or collocates regarding his writing. However, the problematic units of meaning in each learner's writing are so diverse that conventional corpora often prove futile. The search engine Google with the…

  6. Aerospace medicine at Brooks AFB, TX: hail and farewell.

    Science.gov (United States)

    Nunneley, Sarah A; Webb, James T

    2011-05-01

    With the impending termination of USAF operations at Brooks Air Force Base (AFB) in San Antonio, TX, it is time to consider its historic role in Aerospace Medicine. The base was established in 1917 as a flight training center for the U.S. Army Air Service and in 1926 became home to its School of Aviation Medicine. The school moved to San Antonio's Randolph Field in 1931, but in 1959 it returned to Brooks where it occupied new facilities to support its role as a national center for U.S. Air Force aerospace medicine, including teaching, clinical medicine, and research. The mission was then expanded to encompass support of U.S. military and civilian space programs. With the abrupt termination of the military space program in 1969, research at Brooks focused on clinical aviation medicine and support of advanced military aircraft while continuing close cooperation with NASA in support of orbital spaceflight and the journey to the Moon. Reorganization in the 1990s assigned all research functions at Brooks to the Human Systems Division and its successors, leaving to USAFSAM the missions related to clinical work and teaching. In 2002 the USAF and the city of San Antonio implemented shared operation of Brooks as a "City-Base" in the hope of deflecting threatened closure. Nevertheless, under continuing pressure to consolidate military facilities in the United States, the 2005 Base Closure and Realignment Commission ordered Brooks closed by 2011, with its aerospace medicine functions relocated to new facilities at Wright-Patterson AFB in Dayton, OH.

  7. Scroll bar growth on the coastal Trinity River, TX, USA

    Science.gov (United States)

    Mason, J.; Hassenruck-Gudipati, H. J.; Mohrig, D. C.

    2017-12-01

    The processes leading to the formation and growth of scroll bars remain relatively mysterious despite how often they are referenced in fluvial literature. Their definition is descriptive; they are characterized as arcuate topographic highs present on the inner banks of channel bends on meandering rivers, landward of point bars. Often, they are used as proxies for previous positions of point bars. This assumption of a one-to-one correspondence between point bars and scroll bars should be reconsidered as 1) planform curvature for scroll bars is consistently smaller than the curvature for adjacent point bars, and 2) deposition on the scroll bar is typically distinct and disconnected from the adjacent point bar deposition. Results from time-lapse airborne lidar data as well as from trenches through five separate scroll bar - point bar pairings on the Trinity River in east TX, USA, will be discussed in relation to formative scroll bar processes and their connection to point bars. On the lidar difference map, scroll bar growth appears as a strip of increased deposition flanked on both the land- and channel-ward sides by areas with no or limited deposition. Trenches perpendicular to these scrolls typically show a base of dune-scale cross stratification interpreted to be associated with a previous position of the point bar. These dune sets are overlain by sets of climbing-ripple cross-strata that form the core of the modern scroll bar and preserve a record of multiple transport directions (away from, towards, and parallel to the channel). Preliminary Trinity River grain-size analyses show that the constructional scrolls are enriched in all grain sizes less than 250 microns in diameter, while point bars are enriched in all grain sizes above this cut off. Scroll bars are hypothesized to be akin to levees along the inner banks of channels-flow expansion caused by the presence of point bars induces deposition of suspended sediment that defines the positions of the scroll bars.

  8. The Influence of Reference Corpus Size on Wordsmith Tools Keywords Extraction

    Directory of Open Access Journals (Sweden)

    Tony Berber Sardinha

    2012-05-01

    Full Text Available A KeyWords analysis (using WordSmith Tools enables the discovery of lexical items which reveal the main lexical sets in a text or corpus. Such an analysis requires that a reference corpus be compared to the corpus the researcher intends to describe (the study corpus. This paper presents a mathematical method for finding out the influence of reference corpus size on the number of key words extracted by the program. The results reveal that a reference corpus that is at least five times as large as the study corpus allows for drawing an amount of key words that is statistically equivalent to larger reference corpora, thus suggesting five times (as larger as the study corpora as the minimum order of magnitude for reference corpora.

  9. Corpus callosum agenesis: Role of fetal magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Achour Radhouane

    2016-05-01

    Full Text Available Corpus callosum agenesis (CCA was evaluated by ultrasound examination and magnetic resonance imaging (MRI with many studies. Ultrasonography was able to suspect CCA by indirect signs but a definitive diagnosis of CCA was achieved in rare cases. MRI was able to diagnose complete CCA in majority of cases. Additional neurological abnormalities including heterotopia, gyration anomaly, asymmetry of the cerebral hemispheres, and Dandy-Walker variant were documented, as well as an ocular anomaly which was described, by MRI examination. Prenatal counseling for fetal agenesis of the corpus callosum is difficult as the prognosis is uncertain. The association with other cerebral abnormalities increases the likelihood of a poor outcome and ultrasonographic assessment of the fetal brain is limited. We found MRI to be a safe and useful additional procedure to complement ultrasonographic diagnosis or suspicion of CCA.

  10. Cholinergic neurotransmission in human corpus cavernosum. II. Acetylcholine synthesis

    International Nuclear Information System (INIS)

    Blanco, R.; De Tejada, S.; Goldstein, I.; Krane, R.J.; Wotiz, H.H.; Cohen, R.A.

    1988-01-01

    Physiological and histochemical evidence indicates that cholinergic nerves may participate in mediating penile erection. Acetylcholine synthesis and release was studied in isolated human corporal tissue. Human corpus cavernosum incubated with [ 3 H]choline accumulated [ 3 H]choline and synthesized [ 3 H]acethylcholine in an concentration-dependent manner. [ 3 H]Acetylcholine accumulation by the tissue was inhibited by hemicholinium-3, a specific antagonist of the high-affinity choline transport in cholinergic nerves. Transmural electrical field stimulation caused release of [ 3 H]acetylcholine which was significantly diminished by inhibiting neurotransmission with calcium-free physiological salt solution or tetrodotoxin. These observations provide biochemical and physiological evidence for the existence of cholinergic innervation in human corpus cavernosum

  11. MORPOHOLOGICAL POS TAGGING IN ORAL LANGUAGE CORPUS: CHALLENGES FOR AELIUS

    Directory of Open Access Journals (Sweden)

    Gabriel de Ávila Othero

    2014-12-01

    Full Text Available In this paper, we present the results of our work with automatic morphological annotation of excerpts from a corpus of spoken language – belonging to the VARSUL project – using the free morphosyntatic tagger Aelius. We present 20 texts containing 154,530 words, annotated automatically and corrected manually. This paper presents the tagger Aelius and our work of manual review of the texts, as well as our suggestions for improvements of the tool, concerning aspects of oral texts. We verify the performance of morphosyntactic tagging a spoken language corpus, an unprecedented challenge for the tagger. Based on the errors of the tagger, we try to infer certain patterns of annotation to overcome limitations presented by the program, and we propose suggestions for implementations in order to allow Aelius to tag spoken language corpora in a more effective way, specially treating cases such as interjections, apheresis, onomatopeia and conversational markers.

  12. Translating children’s literature: some insights from corpus stylistics

    Directory of Open Access Journals (Sweden)

    Anna Čermáková

    2018-01-01

    Full Text Available In this paper I explore the potential of a corpus stylistic approach to the study of literary translation. The study focuses on translation of children’s literature with its specific constrains, and illustrates with two corpus linguistic techniques: keyword and cluster analysis — specific cases of repetition. So in a broader sense the paper discusses the phenomenon of repetition in different literary (stylistic traditions. These are illustrated by examples from two children’s classics aimed at two different age groups: the Harry Potter and the Winnie the Pooh books — and their translations into Czech. Various shifts in translation, especially in the translation of children’s literature, are often explained by the operation of so-called ‘translation universals’. Though ‘repetition’ as such does not belong to the commonly discussed set of translation universals, the stylistic norms opposing repetition seem to be a strong explanation for the translation shifts identified.

  13. Data for lexicography The central role of the corpus

    Directory of Open Access Journals (Sweden)

    Allan F. Lauder

    2010-10-01

    Full Text Available This paper looks at the nature of data for lexicography and in particular on the central role that electronic corpora can play in providing it. Data has traditionally come from existing dictionaries, citations, and from the lexicographer’s own knowledge of words, through introspection. Each of these is examined and evaluated. Then the electronic corpus is considered. Different kinds of corpora are described and key design criteria are explained, in particular the size of corpus needed for lexicography as well as the issue of representativeness and sampling. The advantages and disadvantages of corpora are weighed and compared against the other types of data. While each of these has benefits, it is argued that corpora are a requirement, not an option, as data for dictionary making.

  14. Cholesterol transport and steroidogenesis by the corpus luteum

    Directory of Open Access Journals (Sweden)

    Christenson Lane K

    2003-11-01

    Full Text Available Abstract The synthesis of progesterone by the corpus luteum is essential for the establishment and maintenance of early pregnancy. Regulation of luteal steroidogenesis can be broken down into three major events; luteinization (i.e., conversion of an ovulatory follicle, luteal regression, and pregnancy induced luteal maintenance/rescue. While the factors that control these events and dictate the final steroid end products are widely varied among different species, the composition of the corpus luteum (luteinized thecal and granulosa cells and the enzymes and proteins involved in the steroidogenic pathway are relatively similar among all species. The key factors involved in luteal steroidogenesis and several new exciting observations regarding regulation of luteal steroidogenic function are discussed in this review.

  15. Techniques and Rules of Ineffability in the Dionysian Corpus

    Directory of Open Access Journals (Sweden)

    Knepper Timothy D.

    2014-06-01

    Full Text Available Is the Dionysian God, or an experience of the Dionysian God, absolutely ineffable? Does the Dionysian corpus assert or perform such ineffability? This paper will argue that the answer to each of these questions is no. The Dionysian God is known hyper-nous as the hyper-ousia cause of all. And the Dionysian corpus unambiguously refers to, asserts of, and metaphorizes about this God just so. In arguing these points, this paper will call upon both the speech act theory of John Searle and the metaphor theory of George Lakoff and Mark Johnson. More particularly, it will look to Searle’s rules of reference and predication and conditions of illocutionary acts, as well as Lakoff and Johnson’s schematization of metaphor gestalt and entailment to show how Dionysian expressions of inexpressibility are rule-governed and the Dionysian God is thereby (relatively effable.

  16. Corpus Linguistics, Network Analysis and Co-occurrence Matrices Corpus Linguistics, Network Analysis and Co-occurrence Matrices

    Directory of Open Access Journals (Sweden)

    Keith Stuart

    2009-12-01

    Full Text Available This article describes research undertaken in order to design a methodology for the reticular representation of knowledge of a specific discourse community. To achieve this goal, a representative corpus of the scientific production of the members of this discourse community (Universidad Politécnica de Valencia, UPV was created. The article presents the practical analysis (frequency, keyword, collocation and cluster analysis that was carried out in the initial phases of the study aimed at establishing the theoretical and practical background and framework for our matrix and network analysis of the scientific discourse of the UPV. In the methodology section, the processes that have allowed us to extract from the corpus the linguistic elements needed to develop co-occurrence matrices, as well as the computer tools used in the research, are described. From these co-occurrence matrices, semantic networks of subject and discipline knowledge were generated. Finally, based on the results obtained, we suggest that it may be viable to extract and to represent the intellectual capital of an academic institution using corpus linguistics methods in combination with the formulations of network theory.En este artículo describimos la investigación que se ha desarrollado en el diseño de una metodología para la representación reticular del conocimiento que se genera en el seno de una institución a partir de un corpus representativo de la producción científica de los integrantes de dicha comunidad discursiva, la Universidad Politécnica de Valencia.. Para ello, presentamos las acciones que se realizaron en las fases iniciales del estudio encaminadas a establecer el marco teórico y práctico en el que se inscribe nuestro análisis. En la sección de metodología se describen las herramientas informáticas utilizadas, así como los procesos que nos permitieron disponer de aquellos elementos presentes en el corpus, que nos llevarían al desarrollo de

  17. Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA

    Directory of Open Access Journals (Sweden)

    Yong Wu

    2014-01-01

    Full Text Available Cone snails express a sophisticated arsenal of small bioactive peptides known as conopeptides or conotoxins (CTxs. Through evolutionary selection, these peptides have gained the ability to interact with a range of ion channels and receptors, such as nicotinic acetylcholine receptors (nAChRs. Here, we used reversed-phase high performance liquid chromatography (RP-HPLC and electrospray ionization-mass spectrometry (ESI-MS to explore the venom peptide diversity of Conus textile, a species of cone snail native to Hainan, China. One fraction of C. textile crude venom potently blocked α3β2 nAChRs. Subsequent purification, synthesis, and tandem mass spectrometric analysis demonstrated that the most active compound in this fraction was identical to α-CTx TxIA, an antagonist of α3β2 nAChRs. Then three disulfide isoforms of α-CTx TxIA were synthesized and their activities were investigated systematically for the first time. As we observed, disulfide isomerisation was particularly important for α-CTx TxIA potency. Although both globular and ribbon isomers showed similar retention times in RP-HPLC, globular TxIA potently inhibited α3β2 nAChRs with an IC50 of 5.4 nM, while ribbon TxIA had an IC50 of 430 nM. In contrast, beads isomer had little activity towards α3β2 nAChRs. Two-step oxidation synthesis produced the highest yield of α-CTx TxIA native globular isomer, while a one-step production process based on random oxidation folding was not suitable. In summary, this study demonstrated the relationship between conotoxin activity and disulfide connectivity on α-CTx TxIA.

  18. A corpus-based approach to generalising a chatbot system

    OpenAIRE

    Abu Shawar, Bayan; Atwell, Eric

    2003-01-01

    International research in NLP is dominated by work on English. NLP techniques and systems can be ported to other natural languages, but this is generally a labour-intensive task, requiring scarce computational and linguistic expertise; hence minority languages are poorly represented in NLP technology. We present an automated approach to porting an NLP technology, the AIML-based chatbot, to new languages, by using a corpus in the target language to retrain the chatbot. We have s...

  19. Tracking Anglicisms in Domains by the Corpus-Linguistic Method

    DEFF Research Database (Denmark)

    Mousten, Birthe; Laursen, Anne Lise

    2015-01-01

    Lay investors and semi-professionals lean on professional stock bloggers and stock analysts for advice on stock investments; semi-professionals and professionals write about investments globally, and stock information has to be available in many local markets. Using the correct terminology......’s critical sense is not enough to make the right choices. Our corpus-linguistic tool can be a help in this specialized field....

  20. Annotated chemical patent corpus: a gold standard for text mining.

    Directory of Open Access Journals (Sweden)

    Saber A Akhondi

    Full Text Available Exploring the chemical and biological space covered by patent applications is crucial in early-stage medicinal chemistry activities. Patent analysis can provide understanding of compound prior art, novelty checking, validation of biological assays, and identification of new starting points for chemical exploration. Extracting chemical and biological entities from patents through manual extraction by expert curators can take substantial amount of time and resources. Text mining methods can help to ease this process. To validate the performance of such methods, a manually annotated patent corpus is essential. In this study we have produced a large gold standard chemical patent corpus. We developed annotation guidelines and selected 200 full patents from the World Intellectual Property Organization, United States Patent and Trademark Office, and European Patent Office. The patents were pre-annotated automatically and made available to four independent annotator groups each consisting of two to ten annotators. The annotators marked chemicals in different subclasses, diseases, targets, and modes of action. Spelling mistakes and spurious line break due to optical character recognition errors were also annotated. A subset of 47 patents was annotated by at least three annotator groups, from which harmonized annotations and inter-annotator agreement scores were derived. One group annotated the full set. The patent corpus includes 400,125 annotations for the full set and 36,537 annotations for the harmonized set. All patents and annotated entities are publicly available at www.biosemantics.org.

  1. MR measurement of normal corpus callosum: Age and sex differentiation

    International Nuclear Information System (INIS)

    Lee, Myung Seob; Kim, Myung Soon; Park, Hyun Ju

    1992-01-01

    Measurement of various portions of the corpus callosum was performed on magnetic resonance(MR) images of 114 subjects with no known or suspected corpus callosal disorders. Midsagittal T1-weighted images used for measurements and mean diameters of various portions in each age and sex group were obtained. Measures of five portions were made: (A) the anterio-posterior length, (B) the diameter of genu position, (C) the diameter of splenium, (D) the diameter of mid-body portion, (E) the diameter of a narrow portion at the body of corpus callosum. The mean diameter in each gender group for A, B, C, D and E were 68.8 mm, 12.1 mm, 12.3 mm, 6,9 mm, 4.1 mm in male and 69.9 mm, 12.0 mm, 12.1 mm, 6.4 mm, 4.1 mm in female, retrospectively. The groups of 0-9 years of both genders showed the minimum mean value in each portion

  2. Mind-modelling with corpus stylistics in David Copperfield.

    Science.gov (United States)

    Stockwell, Peter; Mahlberg, Michaela

    2015-05-01

    We suggest an innovative approach to literary discourse by using corpus linguistic methods to address research questions from cognitive poetics. In this article, we focus on the way that readers engage in mind-modelling in the process of characterisation. The article sets out our cognitive poetic model of characterisation that emphasises the continuity between literary characterisation and real-life human relationships. The model also aims to deal with the modelling of the author's mind in line with the modelling of the minds of fictional characters. Crucially, our approach to mind-modelling is text-driven. Therefore we are able to employ corpus linguistic techniques systematically to identify textual patterns that function as cues triggering character information. In this article, we explore our understanding of mind-modelling through the characterisation of Mr. Dick from David Copperfield by Charles Dickens. Using the CLiC tool (Corpus Linguistics in Cheshire) developed for the exploration of 19th-century fiction, we investigate the textual traces in non-quotations around this character, in order to draw out the techniques of characterisation other than speech presentation. We show that Mr. Dick is a thematically and authorially significant character in the novel, and we move towards a rigorous account of the reader's modelling of authorial intention.

  3. The Gutenberg English Poetry Corpus: Exemplary Quantitative Narrative Analyses

    Directory of Open Access Journals (Sweden)

    Arthur M. Jacobs

    2018-04-01

    Full Text Available This paper describes a corpus of about 3,000 English literary texts with about 250 million words extracted from the Gutenberg project that span a range of genres from both fiction and non-fiction written by more than 130 authors (e.g., Darwin, Dickens, Shakespeare. Quantitative narrative analysis (QNA is used to explore a cleaned subcorpus, the Gutenberg English Poetry Corpus (GEPC, which comprises over 100 poetic texts with around two million words from about 50 authors (e.g., Keats, Joyce, Wordsworth. Some exemplary QNA studies show author similarities based on latent semantic analysis, significant topics for each author or various text-analytic metrics for George Eliot’s poem “How Lisa Loved the King” and James Joyce’s “Chamber Music,” concerning, e.g., lexical diversity or sentiment analysis. The GEPC is particularly suited for research in Digital Humanities, Computational Stylistics, or Neurocognitive Poetics, e.g., as training and test corpus for stimulus development and control in empirical studies.

  4. A case of total agenesis of the corpus callosum

    International Nuclear Information System (INIS)

    Sakamoto, Masanobu; Takeda, Katsuhiko; Bandou, Mitsuaki; Murayama, Shigeo; Sakuta, Manabu

    1985-01-01

    We have reported a case of agenesis of the corpus callosum, in which NMR-CT revealed a complete defect of it, and have examined the localization of the speech center of this patient. The patient is a right-handed 26-year-old man who has complained of headache on the parietal region. His neurological examination revealed only a mild mental difficulty (IQ 77). X-ray CT showed the lateral ventricles to be separated widely and the posterior horns dilated, which were compatible with the agenesis of the corpus callosum. Further, NMR-CT has revealed a total agenesis of the corpus callosum. NMR-CT seems to be highly useful for the detection of the degree of the callosal defect. We have carried out the intracarotid amobarbital injection (Wada's test) for the determination of the lateralization of cerebral speech dominance. It had been reported by some authors that when it comes to the cerebral speech dominance, acallosal patients had no difference between each hemisphere. However, our results have demonstrated a left sided dominance. (author)

  5. Handedness and corpus callosal morphology in Williams syndrome.

    Science.gov (United States)

    Martens, Marilee A; Wilson, Sarah J; Chen, Jian; Wood, Amanda G; Reutens, David C

    2013-02-01

    Williams syndrome is a neurodevelopmental genetic disorder caused by a hemizygous deletion on chromosome 7q11.23, resulting in atypical brain structure and function, including abnormal morphology of the corpus callosum. An influence of handedness on the size of the corpus callosum has been observed in studies of typical individuals, but handedness has not been taken into account in studies of callosal morphology in Williams syndrome. We hypothesized that callosal area is smaller and the size of the splenium and isthmus is reduced in individuals with Williams syndrome compared to healthy controls, and examined age, sex, and handedness effects on corpus callosal area. Structural magnetic resonance imaging scans were obtained on 25 individuals with Williams syndrome (18 right-handed, 7 left-handed) and 25 matched controls. We found that callosal thickness was significantly reduced in the splenium of Williams syndrome individuals compared to controls. We also found novel evidence that the callosal area was smaller in left-handed participants with Williams syndrome than their right-handed counterparts, with opposite findings observed in the control group. This novel finding may be associated with LIM-kinase hemizygosity, a characteristic of Williams syndrome. The findings may have significant clinical implications in future explorations of the Williams syndrome cognitive phenotype.

  6. UNITS OF MEASUREMENT: ORAL TRADITION, TRANSLATION STUDIES AND CORPUS LINGUISTICS

    Directory of Open Access Journals (Sweden)

    John ZEMKE

    2017-06-01

    Full Text Available The study of the world’s verbal arts offers an opportunity to consider ways that computational analysis and modeling of narratives may lead to new understandings of how they are constructed, their dynamics and relationships. Similarly, as corpus linguistics operations must define metrics, it offers an occasion to review basic interpretive concepts such as “units of analysis, context, and genre." My essay begins with an admittedly cursory overview from a novice perspective of what capabilities corpus linguistics currently possesses for the analysis and modeling of narratives. Consideration is given to the epistemological issue in the social sciences with the positivistic prescription or empiricist description of units of analysis and the potential pitfalls or advantages corpus linguistics encounters in searching for adequate equivalent terms. This review leads naturally to reflection on the crucial determinative action of context on meaning and the extent to which current computational interfaces are able to account for and integrate into global analysis of linguistic and performance dimensions such as performer, intonation, gesture, diction, idioms and figurative language, setting, audience, time, and occasion. As a tentative conclusion from this review, it can be stated that artificial intelligence for modeling narratives or devising narrative algorithms must develop capacities to account for performance dimensions in order to fulfill their analytical potential.

  7. MR measurement of normal corpus callosum: Age and sex differentiation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myung Seob; Kim, Myung Soon; Park, Hyun Ju [Wonju College of Medicine, Yonsei University, Wonju (Korea, Republic of)

    1992-07-15

    Measurement of various portions of the corpus callosum was performed on magnetic resonance(MR) images of 114 subjects with no known or suspected corpus callosal disorders. Midsagittal T1-weighted images used for measurements and mean diameters of various portions in each age and sex group were obtained. Measures of five portions were made: (A) the anterio-posterior length, (B) the diameter of genu position, (C) the diameter of splenium, (D) the diameter of mid-body portion, (E) the diameter of a narrow portion at the body of corpus callosum. The mean diameter in each gender group for A, B, C, D and E were 68.8 mm, 12.1 mm, 12.3 mm, 6,9 mm, 4.1 mm in male and 69.9 mm, 12.0 mm, 12.1 mm, 6.4 mm, 4.1 mm in female, retrospectively. The groups of 0-9 years of both genders showed the minimum mean value in each portion.

  8. Agenesis of the corpus callosum and autism: a comprehensive comparison.

    Science.gov (United States)

    Paul, Lynn K; Corsello, Christina; Kennedy, Daniel P; Adolphs, Ralph

    2014-06-01

    The corpus callosum, with its ∼200 million axons, remains enigmatic in its contribution to cognition and behaviour. Agenesis of the corpus callosum is a congenital condition in which the corpus callosum fails to develop; such individuals exhibit localized deficits in non-literal language comprehension, humour, theory of mind and social reasoning. These findings together with parent reports suggest that behavioural and cognitive impairments in subjects with callosal agenesis may overlap with the profile of autism spectrum disorders, particularly with respect to impairments in social interaction and communication. To provide a comprehensive test of this hypothesis, we directly compared a group of 26 adults with callosal agenesis to a group of 28 adults with a diagnosis of autism spectrum disorder but no neurological abnormality. All participants had full-scale intelligence quotient scores >78 and groups were matched on age, handedness, and gender ratio. Using the Autism Diagnostic Observation Schedule together with current clinical presentation to assess autistic symptomatology, we found that 8/26 (about a third) of agenesis subjects presented with autism. However, more formal diagnosis additionally involving recollective parent-report measures regarding childhood behaviour showed that only 3/22 met complete formal criteria for an autism spectrum disorder (parent reports were unavailable for four subjects). We found no relationship between intelligence quotient and autism symptomatology in callosal agenesis, nor evidence that the presence of any residual corpus callosum differentiated those who exhibited current autism spectrum symptoms from those who did not. Relative to the autism spectrum comparison group, parent ratings of childhood behaviour indicated children with agenesis were less likely to meet diagnostic criteria for autism, even for those who met autism spectrum criteria as adults, and even though there was no group difference in parent report of current

  9. RCRA Assessment Plan for Single-Shell Tank Waste Management Area TX-TY

    Energy Technology Data Exchange (ETDEWEB)

    Horton, Duane G.

    2007-03-26

    WMA TX-TY contains underground, single-shell tanks that were used to store liquid waste that contained chemicals and radionuclides. Most of the liquid has been removed, and the remaining waste is regulated under the RCRA as modi¬fied in 40 CFR Part 265, Subpart F and Washington State’s Hazardous Waste Management Act . WMA TX-TY was placed in assessment monitoring in 1993 because of elevated specific conductance. A groundwater quality assessment plan was written in 1993 describing the monitoring activities to be used in deciding whether WMA TX-TY had affected groundwater. That plan was updated in 2001 for continued RCRA groundwater quality assessment as required by 40 CFR 265.93 (d)(7). This document further updates the assessment plan for WMA TX-TY by including (1) information obtained from ten new wells installed at the WMA after 1999 and (2) information from routine quarterly groundwater monitoring during the last five years. Also, this plan describes activities for continuing the groundwater assessment at WMA TX TY.

  10. 77 FR 58368 - Notice of Application

    Science.gov (United States)

    2012-09-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Application Corpus Christi... application in Docket No. CP12-507-000, under section 3(a) of the Natural Gas Act (NGA), as amended, and parts... Christi LNG, LLC LNG import terminal. In the same application, Cheniere Corpus Christi Pipeline, L.P. (CCP...

  11. Radiating Elements for Shared Aperture Tx/Rx Phased Arrays at K/Ka Band

    KAUST Repository

    Sandhu, Ali Imran; Arnieri, E.; Amendola, Giandomenico; Boccia, L.; Meniconi, Erika; Ziegler, Volker

    2016-01-01

    A dual band, Tx/Rx, self-diplexing phased array is presented. The antenna has been designed to cover Tx/Rx satellite communications at K/Ka band with a frequency ratio 1.5:1. To obtain dual band operations with a single radiating surface, a novel dual band radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The proposed configuration reduces the number of radiating elements required by other solutions while avoiding the insurgence of grating lobes. The tightly packed arrangement of the elements poses many integration issues, which are solved with a novel integration technique. The array elements are optimized to scan the beam in excess of ° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  12. Hanford Tank Farms Vadose Zone, Addendum to the TX Tank Farm Report

    International Nuclear Information System (INIS)

    Spatz, R.

    2000-01-01

    This addendum to the TX Tank Farm Report (GJO-97-13-TAR, GJO-HAN-11) published in September 1997 incorporates the results of high-rate and repeat logging activities along with shape factor analysis of the logging data. A high-rate logging system was developed and deployed in the TX Tank Farm to measure cesium-137 concentration levels in high gamma flux zones where the spectral gamma logging system was unable to collect usable data because of high dead times and detector saturation. This report presents additional data and revised visualizations of subsurface contaminant distribution in the TX Tank Farm at the DOE Hanford Site in the state of Washington

  13. Radiating Elements for Shared Aperture Tx/Rx Phased Arrays at K/Ka Band

    KAUST Repository

    Sandhu, Ali Imran

    2016-04-11

    A dual band, Tx/Rx, self-diplexing phased array is presented. The antenna has been designed to cover Tx/Rx satellite communications at K/Ka band with a frequency ratio 1.5:1. To obtain dual band operations with a single radiating surface, a novel dual band radiator is adopted and placed in a configuration in which dual band and single band elements are interleaved. The proposed configuration reduces the number of radiating elements required by other solutions while avoiding the insurgence of grating lobes. The tightly packed arrangement of the elements poses many integration issues, which are solved with a novel integration technique. The array elements are optimized to scan the beam in excess of ° in both bands. A subarray with 49 Rx elements and 105 Tx elements was built and measured confirming the results obtained in simulations.

  14. Characterization, antibacterial, and neurotoxic effect of Green synthesized nanosilver using Ziziphus spina Christi aqueous leaf extract collected from Riyadh, Saudi Arabia

    Science.gov (United States)

    El-Ansary, Afaf; Warsy, Arjumand; Daghestani, Maha; Merghani, Nada M.; Al-Dbass, Abeer; Bukhari, Wadha; Al-Ojayan, Badryah; Ibrahim, Eiman M.; Al-Qahtani, Asma M.; Shafi Bhat, Ramesa

    2018-02-01

    The current study aims to synthesize silver nanoparticles using Ziziphus spina Christi (ZSC) or (Sidr) aqueous leaf extract collected from Riyadh, Saudi Arabia. The green synthesis of silver nanoparticles using sidr leaves extract was successful. Production of silver nanoparticles was confirmed through UV-vis Spectrophotometer, particles size and zeta potential analysis, Infra-red spectroscopy, Scanning, and Transmission Electron Microscope (SEM and TEM). The UV-visible spectra showed that the absorption peak existed at 400 nm. SEM analysis showed that the synthesized AgNPs were spherical but in slightly aggregated form. TEM demonstrated different size range of 4-33 nm with an average size of 13. The element analysis profile showed silver signal together with oxygen, calcium, and potassium peaks which might be related to the plant structure. Biological effects of the synthesized AgNPs exhibit satisfactory inhibitory effect against ten tested microorganisms. It inhibited the growth of 5 gram-positive and five gram-negative bacteria. Moreover, AgNPs demonstrated a synergistic effect on the neurotoxicity induced in rat pups with orally administered methyl mercury (MeHg). The present study showed that AgNPs prepared from ZSC might be a promising antimicrobial agent for successful treatment of bacterial infection in intensive care units (ICU) especially in case of antibiotic resistance.

  15. Tank 241-TX-105 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-TX-105 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-TX-105 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  16. Tank 241-TX-118 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-TX-118 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-TX-118 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  17. Ruptured corpus luteal cyst: Prediction of clinical outcomes with CT

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myoung Seok; Moon, Min Hoan; Woo, Hyun Sik; Sung, Chang Kyu; Jeon, Hye Won; Lee, Taek Sang [SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2017-08-01

    To evaluate the determinant pretreatment CT findings that can predict surgical intervention for patients suffering from corpus luteal cyst rupture with hemoperitoneum. From January 2009 to December 2014, a total of 106 female patients (mean age, 26.1 years; range, 17–44 years) who visited the emergency room of our institute for acute abdominal pain and were subsequently diagnosed with ruptured corpus luteal cyst with hemoperitoneum were included in the retrospective study. The analysis of CT findings included cyst size, cyst shape, sentinel clot sign, ring of fire sign, hemoperitoneum depth, active bleeding in portal phase and attenuation of hemoperitoneum. The comparison of CT findings between the surgery and conservative management groups was performed with the Mann-Whitney U test or chi-square test. Logistic regression analysis was used to determine significant CT findings in predicting surgical intervention for a ruptured cyst. Comparative analysis revealed that the presence of active bleeding and the hemoperitoneum depth were significantly different between the surgery and conservative management groups and were confirmed as significant CT findings for predicting surgery, with adjusted odds ratio (ORs) of 3.773 and 1.318, respectively (p < 0.01). On the receiver-operating characteristic curve analysis for hemoperitoneum depth, the optimal cut-off value was 5.8 cm with 73.7% sensitivity and 58.6% specificity (Az = 0.711, p = 0.004). In cases with a hemoperitoneum depth > 5.8 cm and concurrent active bleeding, the OR for surgery increased to 5.786. The presence of active bleeding and the hemoperitoneum depth on a pretreatment CT scan can be predictive warning signs of surgery for a patient with a ruptured corpus luteal cyst with hemoperitoneum.

  18. Exploring the Potential of Corpus Use in Translation Training

    DEFF Research Database (Denmark)

    Laursen, Anne Lise; Pellón, Ismael Arinas

    2014-01-01

    translators only allows for teaching the students methods that they can apply systematically to several professional tasks. The chapter illustrates how the traditional translation training strategies can be combined with the use of concordancing software to cope with translations.......The chapter describes the corpus analysis strategies used with the translation master’s students at the Department of Business Communication at the Faculty of Business and Social Sciences (formerly Aarhus School of Business or ASB). The short time available for the training of specialized...

  19. Bollywood Movie Corpus for Text, Images and Videos

    OpenAIRE

    Madaan, Nishtha; Mehta, Sameep; Saxena, Mayank; Aggarwal, Aditi; Agrawaal, Taneea S; Malhotra, Vrinda

    2017-01-01

    In past few years, several data-sets have been released for text and images. We present an approach to create the data-set for use in detecting and removing gender bias from text. We also include a set of challenges we have faced while creating this corpora. In this work, we have worked with movie data from Wikipedia plots and movie trailers from YouTube. Our Bollywood Movie corpus contains 4000 movies extracted from Wikipedia and 880 trailers extracted from YouTube which were released from 1...

  20. Inner change in the Corpus Paulinum: pointers for pastoral counselling

    Directory of Open Access Journals (Sweden)

    Y. Campbell-Lane

    2007-07-01

    Full Text Available The aim of this article is to establish what perspectives exist on inner change within the “Corpus Paulinum” and how it should be applied in pastoral counselling. The Scriptural guidelines of change that will be examined for the purposes of this article, are found in the following references: Ephesians 4:22-24, Colos- sians 3:8-10, and Romans 12:1-2. The work of the Holy Spirit as “Agent of change” will also be discussed and finally some pointers on inner change and the implications for pastoral counselling will be proposed.

  1. 76 FR 33333 - Use of Small Area Fair Market Rents for Project Base Vouchers in the Dallas TX Metropolitan Area

    Science.gov (United States)

    2011-06-08

    ... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5525-N-01] Use of Small Area Fair Market Rents for Project Base Vouchers in the Dallas TX Metropolitan Area AGENCY: Office of the Assistant... Small Area Fair Market Rents (SAFMRs) for Project-Based Vouchers (PBVs) located in the Dallas, TX...

  2. 78 FR 73109 - Radio Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK; Rule and...

    Science.gov (United States)

    2013-12-05

    ... Broadcasting Services; Benjamin and Cisco, TX; De Beque, CO; Port Lions, AK; Rule and Shamrock, TX AGENCY... 237C3 at Benjamin, Texas; Channel 261C3 at Cisco, Texas; Channel 288C2 at Rule, Texas; and Channel 225C2..., Channel 237C3; by removing Cisco, Channel 261C3; by removing Channel 288C2 at Rule; and by removing...

  3. Inherent Electrochemistry and Charge Transfer Properties of Few-Layer Two Dimensional Ti3C2Tx MXene

    KAUST Repository

    Nayak, Pranati

    2018-05-25

    We report the effect of Ti3C2Tx MXene flake thickness on its inherent electrochemistry and heterogeneous charge transfer characteristics. It is shown that the Ti3C2Tx undergoes irreversible oxidation in the positive potential window, which strongly depends on the flake thickness and pH of the electrolyte. Few-layer Ti3C2Tx exhibits faster electron transfer kinetics (k0=0.09533 cm/s) with Fe(CN)64−/3− redox mediator compared to multi-layer Ti3C2Tx (k0= 0.00503 cm/s). In addition, few-layer free standing Ti3C2Tx film electrode remains intact after enduring irreversible oxidation.

  4. Inherent Electrochemistry and Charge Transfer Properties of Few-Layer Two Dimensional Ti3C2Tx MXene

    KAUST Repository

    Nayak, Pranati; Jiang, Qiu; Mohanraman, Rajeshkumar; Anjum, Dalaver H.; Hedhili, Mohamed N.; Alshareef, Husam N.

    2018-01-01

    We report the effect of Ti3C2Tx MXene flake thickness on its inherent electrochemistry and heterogeneous charge transfer characteristics. It is shown that the Ti3C2Tx undergoes irreversible oxidation in the positive potential window, which strongly depends on the flake thickness and pH of the electrolyte. Few-layer Ti3C2Tx exhibits faster electron transfer kinetics (k0=0.09533 cm/s) with Fe(CN)64−/3− redox mediator compared to multi-layer Ti3C2Tx (k0= 0.00503 cm/s). In addition, few-layer free standing Ti3C2Tx film electrode remains intact after enduring irreversible oxidation.

  5. Emotional Intelligence in Agenesis of the Corpus Callosum.

    Science.gov (United States)

    Anderson, Luke B; Paul, Lynn K; Brown, Warren S

    2017-05-01

    People with agenesis of the corpus callosum (AgCC) with normal general intelligence have deficits in complex cognitive processing, as well as in social cognition. It is uncertain the extent to which impoverished processing of emotions may contribute to social processing deficiencies. We used the Mayer-Salovey-Caruso Emotional Intelligence Test to clarify the nature of emotional intelligence in 16 adults with AgCC. As hypothesized, persons with AgCC exhibited greater disparities from norms on tests involving more socially complex aspects of emotions. The AgCC group did not differ from norms on the Experiential subscale, but they were significantly below norms on the Strategic subscale. These findings suggest that the corpus callosum is not essential for experiencing and thinking about basic emotions in a "normal" way, but is necessary for more complex processes involving emotions in the context of social interactions. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Revisiting corpus creation and analysis tools for translation tasks

    Directory of Open Access Journals (Sweden)

    Claudio Fantinuoli

    2016-06-01

    Full Text Available Many translation scholars have proposed the use of corpora to allow professional translators to produce high quality texts which read like originals. Yet, the diffusion of this methodology has been modest, one reason being the fact that software for corpora analyses have been developed with the linguist in mind, which means that they are generally complex and cumbersome, offering many advanced features, but lacking the level of usability and the specific features that meet translators’ needs. To overcome this shortcoming, we have developed TranslatorBank, a free corpus creation and analysis tool designed for translation tasks. TranslatorBank supports the creation of specialized monolingual corpora from the web; it includes a concordancer with a query system similar to a search engine; it uses basic statistical measures to indicate the reliability of results; it accesses the original documents directly for more contextual information; it includes a statistical and linguistic terminology extraction utility to extract the relevant terminology of the domain and the typical collocations of a given term. Designed to be easy and intuitive to use, the tool may help translation students as well as professionals to increase their translation quality by adhering to the specific linguistic variety of the target text corpus.

  7. Corpus callosotomy in a patient with startle epilepsy.

    Science.gov (United States)

    Gómez, Nicolás Garófalo; Hamad, Ana Paula; Marinho, Murilo; Tavares, Igor M; Carrete, Henrique; Caboclo, Luís Otávio; Yacubian, Elza Márcia; Centeno, Ricardo

    2013-03-01

    Startle epilepsy is a syndrome of reflex epilepsy in which the seizures are precipitated by a sudden and surprising, usually auditory, stimulus. We describe herein a girl who had been suffering with startle-induced seizures since 2 years of age. She had focal, tonic and tonic-clonic seizures, refractory to antiepileptic treatment. Daily tonic seizures led to very frequent falls and morbidity. Neurologically, she had no deficit. Interictal EEG showed slow waves and epileptiform discharges in central and fronto-central regions. Video-polygraphic recordings of seizures, triggered by stimuli, showed generalised symmetric tonic posturing with ictal EEG, characterised by an abrupt and diffuse electrodecremental pattern of fast activity, followed by alpha-theta rhythm superimposed by epileptic discharges predominantly over the vertex and anterior regions. Magnetic resonance imaging showed no abnormalities. Corpus callosotomy was performed when the patient was 17. Since surgery, the patient (one year follow-up) has remained seizure-free. Corpus callosotomy may be considered in patients with startle epilepsy and tonic seizures, in the absence of focal lesions amenable to surgery. [Published with video sequences].

  8. The significance of estradiol metabolites in human corpus luteum physiology.

    Science.gov (United States)

    Devoto, Luigi; Henríquez, Soledad; Kohen, Paulina; Strauss, Jerome F

    2017-07-01

    The human corpus luteum (CL) is a temporary endocrine gland derived from the ovulated follicle. Its formation and limited lifespan is critical for steroid hormone production required to support menstrual cyclicity, endometrial receptivity for successful implantation, and the maintenance of early pregnancy. Endocrine and paracrine-autocrine molecular mechanisms associated with progesterone production throughout the luteal phase are critical for the development, maintenance, regression, and rescue by hCG which sustains CL function into early pregnancy. However, the signaling systems driving the regression of the primate corpus luteum in non-conception cycles are not well understood. Recently, there has been interest in the functional roles of estradiol metabolites (EMs), mostly in estrogen-producing tissues. The human CL produces a number of EMs, and it has been postulated that the EMs acting via paracrine-autocrine pathways affect angiogenesis or LH-mediated events. The present review describes advances in understanding the role of EMs in the functional lifespan and regression of the human CL in non-conception cycles. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Organising white matter in a brain without corpus callosum fibres.

    Science.gov (United States)

    Bénézit, Audrey; Hertz-Pannier, Lucie; Dehaene-Lambertz, Ghislaine; Monzalvo, Karla; Germanaud, David; Duclap, Delphine; Guevara, Pamela; Mangin, Jean-François; Poupon, Cyril; Moutard, Marie-Laure; Dubois, Jessica

    2015-02-01

    Isolated corpus callosum dysgenesis (CCD) is a congenital malformation which occurs during early development of the brain. In this study, we aimed to identify and describe its consequences beyond the lack of callosal fibres, on the morphology, microstructure and asymmetries of the main white matter bundles with diffusion imaging and fibre tractography. Seven children aged between 9 and 13 years old and seven age- and gender-matched control children were studied. First, we focused on bundles within the mesial region of the cerebral hemispheres: the corpus callosum, Probst bundles and cingulum which were selected using a conventional region-based approach. We demonstrated that the Probst bundles have a wider connectivity than the previously described rostrocaudal direction, and a microstructure rather distinct from the cingulum but relatively close to callosal remnant fibres. A sigmoid bundle was found in two partial ageneses. Second, the corticospinal tract, thalamic radiations and association bundles were extracted automatically via an atlas of adult white matter bundles to overcome bias resulting from a priori knowledge of the bundles' anatomical morphology and trajectory. Despite the lack of callosal fibres and the colpocephaly observed in CCD, all major white matter bundles were identified with a relatively normal morphology, and preserved microstructure (i.e. fractional anisotropy, mean diffusivity) and asymmetries. Consequently the bundles' organisation seems well conserved in brains with CCD. These results await further investigations with functional imaging before apprehending the cognition variability in children with isolated dysgenesis. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. A human language corpus for interstellar message construction

    Science.gov (United States)

    Elliott, John

    2011-02-01

    The aim of HuLCC (the human language chorus corpus), is to provide a resource of sufficient size to facilitate inter-language analysis by incorporating languages from all the major language families: for the first time all aspects of typology will be incorporated within a single corpus, adhering to a consistent grammatical classification and granularity, which historically adopt a plethora of disparate schemes. An added feature will be the inclusion of a common text element, which will be translated across all languages, to provide a precise comparable thread for detailed linguistic analysis for translation strategies and a mechanism by which these mappings can be explicitly achieved. Methods developed to solve unambiguous mappings across these languages can then be adopted for any subsequent message authored by the SETI community. Initially, it is planned to provide at least 20,000 words for each chosen language, as this amount of text exceeds the point where randomly generated text can be disambiguated from natural language and is of sufficient size useful for message transmission [1] (Elliot, 2002). This paper details the design of this resource, which ultimately will be made available to SETI upon its completion, and discusses issues 'core' to any message construction.

  11. Revisiting corpus creation and analysis tools for translation tasks

    Directory of Open Access Journals (Sweden)

    Claudio Fantinuoli

    2016-04-01

    Many translation scholars have proposed the use of corpora to allow professional translators to produce high quality texts which read like originals. Yet, the diffusion of this methodology has been modest, one reason being the fact that software for corpora analyses have been developed with the linguist in mind, which means that they are generally complex and cumbersome, offering many advanced features, but lacking the level of usability and the specific features that meet translators’ needs. To overcome this shortcoming, we have developed TranslatorBank, a free corpus creation and analysis tool designed for translation tasks. TranslatorBank supports the creation of specialized monolingual corpora from the web; it includes a concordancer with a query system similar to a search engine; it uses basic statistical measures to indicate the reliability of results; it accesses the original documents directly for more contextual information; it includes a statistical and linguistic terminology extraction utility to extract the relevant terminology of the domain and the typical collocations of a given term. Designed to be easy and intuitive to use, the tool may help translation students as well as professionals to increase their translation quality by adhering to the specific linguistic variety of the target text corpus.

  12. 76 FR 12788 - Environmental Impact Statement for a Proposed Urban Rail system in Austin, TX

    Science.gov (United States)

    2011-03-08

    ... Conference Center (Classroom 103 on first floor), 1900 University Avenue, Austin, TX 78705, Telephone (512...'' (Executive Order 11991, of May 24, 1977). Transit projects may also generate environmental benefits; these... evaluated potential route, technology, and investment alternatives. The CATS is posted on the project Web...

  13. Preliminary tank characterization report for single-shell tank 241-TX-110: Best-basis inventory

    International Nuclear Information System (INIS)

    Place, D.E.

    1997-01-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-110 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task

  14. 75 FR 52065 - SharePlus Federal Bank, Plano, TX; Approval of Conversion Application

    Science.gov (United States)

    2010-08-24

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [AC-50: OTS Nos. 17972 and H4743] SharePlus Federal Bank, Plano, TX; Approval of Conversion Application Notice is hereby given that on August 12, 2010, the Office of Thrift Supervision approved the application of SharePlus Federal Bank, Piano...

  15. 77 FR 44582 - Reorganization of Foreign-Trade Zone 183 Under Alternative Site Framework; Austin, TX

    Science.gov (United States)

    2012-07-30

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1843] Reorganization of Foreign-Trade Zone 183 Under Alternative Site Framework; Austin, TX Pursuant to its authority under the Foreign-Trade... Austin Customs and Border Protection port of entry, and FTZ 183's existing Sites 1 through 24 would be...

  16. 76 FR 73587 - Foreign-Trade Zone 183-Austin, Tx; Site Renumbering Notice

    Science.gov (United States)

    2011-11-29

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 183--Austin, Tx; Site... (Board Order 1366). FTZ 183 currently consists of 8 ``sites'' totaling some 2,818 acres in the Austin... Austin Enterprise Zone, located at Bolm Road and Gardner Road, Austin; Site 2 (50 acres)--Balcones...

  17. 76 FR 9640 - Prevailing Rate Systems: Santa Clara, CA, Tulsa County, OK, and Angelina County, TX

    Science.gov (United States)

    2011-02-22

    ... OFFICE OF PERSONNEL MANAGEMENT 5 CFR Part 532 RIN 3206-AM22 Prevailing Rate Systems: Santa Clara... County, Texas, as an area of application to the Dallas, TX, NAF FWS wage area. The Federal Prevailing.... Accordingly, the U.S. Office of Personnel Management amends 5 CFR part 532 as follows: PART 532--PREVAILING...

  18. 75 FR 58339 - Prevailing Rate Systems; Redefinition of the Shreveport, LA; Texarkana, TX; Milwaukee, WI; and...

    Science.gov (United States)

    2010-09-24

    ... 3206-AM28 Prevailing Rate Systems; Redefinition of the Shreveport, LA; Texarkana, TX; Milwaukee, WI... area. These changes are based on recent consensus recommendations of the Federal Prevailing Rate... below. The Federal Prevailing Rate Advisory Committee (FPRAC), the national labor-management committee...

  19. Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool.

    Science.gov (United States)

    Moore, Simon J; Lai, Hung-En; Needham, Hannah; Polizzi, Karen M; Freemont, Paul S

    2017-04-01

    Streptomyces venezuelae is a promising chassis in synthetic biology for fine chemical and secondary metabolite pathway engineering. The potential of S. venezuelae could be further realized by expanding its capability with the introduction of its own in vitro transcription-translation (TX-TL) system. TX-TL is a fast and expanding technology for bottom-up design of complex gene expression tools, biosensors and protein manufacturing. Herein, we introduce a S. venezuelae TX-TL platform by reporting a streamlined protocol for cell-extract preparation, demonstrating high-yield synthesis of a codon-optimized sfGFP reporter and the prototyping of a synthetic tetracycline-inducible promoter in S. venezuelae TX-TL based on the tetO-TetR repressor system. The aim of this system is to provide a host for the homologous production of exotic enzymes from Actinobacteria secondary metabolism in vitro. As an example, the authors demonstrate the soluble synthesis of a selection of enzymes (12-70 kDa) from the Streptomyces rimosus oxytetracycline pathway. © 2017 The Authors. Biotechnology Journal published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. 75 FR 54695 - Noise Exposure Map Notice; Brownsville South Padre Island International Airport, Brownsville, TX

    Science.gov (United States)

    2010-09-08

    ...; Brownsville South Padre Island International Airport, Brownsville, TX AGENCY: Federal Aviation Administration... that the noise exposure maps submitted by the City of Brownsville, Texas for Brownsville South Padre... that the noise exposure maps submitted for Brownsville South Padre Island International Airport are in...

  1. 75 FR 8994 - Certification of the Attorney General; Williamson County, TX

    Science.gov (United States)

    2010-02-26

    ... DEPARTMENT OF JUSTICE Certification of the Attorney General; Williamson County, TX In accordance... within the scope of the determinations of the Attorney General and the Director of the Census made under... September 23, 1975 (40 FR 43,746). Dated: February 23, 2010. Eric H. Holder Jr., Attorney General of the...

  2. Texas Higher Education Strategic Plan: 2015-2030. 60x30TX

    Science.gov (United States)

    Texas Higher Education Coordinating Board, 2015

    2015-01-01

    Higher education improves the lives of Texans. This new higher education plan, 60x30TX, focuses on the common goal by striving for 60 percent of the 25- to 34-year-old Texas population to hold a certificate or degree by 2030. The plan seeks to increase student success through the combined expertise and resources of many stakeholders. Because of…

  3. 76 FR 77245 - Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX...

    Science.gov (United States)

    2011-12-12

    ...-FF02R06000] Attwater Prairie Chicken National Wildlife Refuge, Austin and Colorado Counties, TX... (EA) for Attwater Prairie Chicken National Wildlife Refuge (Refuge, NWR), located approximately 60... Prairie Chicken NWR draft CCP and EA'' in the subject line of the message. Fax: Attn: Monica Kimbrough...

  4. Preliminary tank characterization report for single-shell tank 241-TX-116: best-basis inventory

    International Nuclear Information System (INIS)

    Place, D.E.

    1997-01-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-116 was performed, and a bost-basis inventory was established. This work follows the methodology that was established by the standard inventory task

  5. 78 FR 52714 - Proposed Amendment of Class E Airspace; Gainesville, TX

    Science.gov (United States)

    2013-08-26

    ...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend Class E airspace at Gainesville, TX. Decommissioning of the Gainesville radio... developing reasoned regulatory decisions on the proposal. Comments are specifically invited on the overall...

  6. Pengaruh Customer Experience Dan Kepercayaan Terhadap Kepuasan Konsumen Di Tx Travel Klampis

    OpenAIRE

    Salim, Kenny Febrina; Catherine, Catherine; Andreani, Fransisca

    2015-01-01

    Penelitian ini bertujuan untuk mengetahui pengaruh customer experience dan kepercayaan terhadap kepuasan konsumen yang ada di TX Travel Klampis Surabaya. Penelitian ini menggunakan metode kuantitatif dengan regresi linear berganda. Berdasarkan hasil pengolahan data, dapat disimpulkan bahwa pengaruh customer experience dan kepercayaan terhadap kepuasan konsumen berpengaruh positif dan signifikan, akan tetapi customer experience memiliki pengaruh yang lebih dominan dan signifikan terhadap kepua...

  7. 33 CFR 165.813 - Security Zones; Ports of Houston and Galveston, TX.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Security Zones; Ports of Houston... Security Zones; Ports of Houston and Galveston, TX. (a) Location. Within the Ports of Houston and Galveston... yards of a cruise ship unless expressly authorized by the Coast Guard Captain of the Port Houston...

  8. 76 FR 30396 - Deloitte Financial Advisory Services LLP, Real Estate Consulting, Houston, TX; Amended...

    Science.gov (United States)

    2011-05-25

    ... Advisory Services LLP, Real Estate Consulting, Houston, TX; Amended Certification Regarding Eligibility To... Financial Advisory Services LLP, Real Estate Consulting, Houston, Texas (subject firm). The Department's... Services LLP, Real Estate Consulting, Houston, Texas who were adversely affected by a shift in services to...

  9. 75 FR 8742 - Notice of Inventory Completion: Stephen F. Austin State University, Nacogdoches, TX

    Science.gov (United States)

    2010-02-25

    ... DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Stephen F. Austin... control of Stephen F. Austin State University, Nacogdoches, TX. The human remains and associated funerary..., which was under contract with Stephen F. Austin State University. In the early 1900s, human remains...

  10. NA62 Level 0 trigger: TELDES, TX mezzanine, RX mezzanine integration scenario

    CERN Multimedia

    Lupi, Matteo

    2015-01-01

    TELDES is a TEL62 daughter-board used in the generation of the Liquid Krypton Calorimeter primitive for the Level 0 Trigger of the NA62 Experiment. TX and RX mezzanines are daughter boards used in the same trigger system to communicate between different levels of the trigger.

  11. Corpus callosum thickness in children: an MR pattern-recognition approach on the midsagittal image

    Energy Technology Data Exchange (ETDEWEB)

    Andronikou, Savvas; Pillay, Tanyia; Gabuza, Lungile; Mahomed, Nasreen; Naidoo, Jaishree; Tebogo Hlabangana, Linda [University of the Witwatersrand, Radiology Department, Faculty of Health Sciences, Johannesburg (South Africa); Du Plessis, Vicci [University of KwaZulu-Natal, Radiology Department, Faculty of Health Sciences, Durban (South Africa); Prabhu, Sanjay P. [Harvard Medical School, Department of Radiology, Boston Children' s Hospital, Boston, MA (United States)

    2014-08-31

    Thickening of the corpus callosum is an important feature of development, whereas thinning of the corpus callosum can be the result of a number of diseases that affect development or cause destruction of the corpus callosum. Corpus callosum thickness reflects the volume of the hemispheres and responds to changes through direct effects or through Wallerian degeneration. It is therefore not only important to evaluate the morphology of the corpus callosum for congenital anomalies but also to evaluate the thickness of specific components or the whole corpus callosum in association with other findings. The goal of this pictorial review is raise awareness that the thickness of the corpus callosum can be a useful feature of pathology in pediatric central nervous system disease and must be considered in the context of the stage of development of a child. Thinning of the corpus callosum can be primary or secondary, and generalized or focal. Primary thinning is caused by abnormal or failed myelination related to the hypomyelinating leukoencephalopathies, metabolic disorders affecting white matter, and microcephaly. Secondary thinning of the corpus callosum can be caused by diffuse injury such as hypoxic-ischemic encephalopathy, human immunodeficiency virus (HIV) encephalopathy, hydrocephalus, dysmyelinating conditions and demyelinating conditions. Focal disturbance of formation or focal injury also causes localized thinning, e.g., callosal dysgenesis, metabolic disorders with localized effects, hypoglycemia, white matter injury of prematurity, HIV-related atrophy, infarction and vasculitis, trauma and toxins. The corpus callosum might be too thick because of a primary disorder in which the corpus callosum finding is essential to diagnosis; abnormal thickening can also be secondary to inflammation, infection and trauma. (orig.)

  12. Building a comprehensive syntactic and semantic corpus of Chinese clinical texts.

    Science.gov (United States)

    He, Bin; Dong, Bin; Guan, Yi; Yang, Jinfeng; Jiang, Zhipeng; Yu, Qiubin; Cheng, Jianyi; Qu, Chunyan

    2017-05-01

    To build a comprehensive corpus covering syntactic and semantic annotations of Chinese clinical texts with corresponding annotation guidelines and methods as well as to develop tools trained on the annotated corpus, which supplies baselines for research on Chinese texts in the clinical domain. An iterative annotation method was proposed to train annotators and to develop annotation guidelines. Then, by using annotation quality assurance measures, a comprehensive corpus was built, containing annotations of part-of-speech (POS) tags, syntactic tags, entities, assertions, and relations. Inter-annotator agreement (IAA) was calculated to evaluate the annotation quality and a Chinese clinical text processing and information extraction system (CCTPIES) was developed based on our annotated corpus. The syntactic corpus consists of 138 Chinese clinical documents with 47,426 tokens and 2612 full parsing trees, while the semantic corpus includes 992 documents that annotated 39,511 entities with their assertions and 7693 relations. IAA evaluation shows that this comprehensive corpus is of good quality, and the system modules are effective. The annotated corpus makes a considerable contribution to natural language processing (NLP) research into Chinese texts in the clinical domain. However, this corpus has a number of limitations. Some additional types of clinical text should be introduced to improve corpus coverage and active learning methods should be utilized to promote annotation efficiency. In this study, several annotation guidelines and an annotation method for Chinese clinical texts were proposed, and a comprehensive corpus with its NLP modules were constructed, providing a foundation for further study of applying NLP techniques to Chinese texts in the clinical domain. Copyright © 2017. Published by Elsevier Inc.

  13. Corpus callosum thickness in children: an MR pattern-recognition approach on the midsagittal image

    International Nuclear Information System (INIS)

    Andronikou, Savvas; Pillay, Tanyia; Gabuza, Lungile; Mahomed, Nasreen; Naidoo, Jaishree; Tebogo Hlabangana, Linda; Du Plessis, Vicci; Prabhu, Sanjay P.

    2015-01-01

    Thickening of the corpus callosum is an important feature of development, whereas thinning of the corpus callosum can be the result of a number of diseases that affect development or cause destruction of the corpus callosum. Corpus callosum thickness reflects the volume of the hemispheres and responds to changes through direct effects or through Wallerian degeneration. It is therefore not only important to evaluate the morphology of the corpus callosum for congenital anomalies but also to evaluate the thickness of specific components or the whole corpus callosum in association with other findings. The goal of this pictorial review is raise awareness that the thickness of the corpus callosum can be a useful feature of pathology in pediatric central nervous system disease and must be considered in the context of the stage of development of a child. Thinning of the corpus callosum can be primary or secondary, and generalized or focal. Primary thinning is caused by abnormal or failed myelination related to the hypomyelinating leukoencephalopathies, metabolic disorders affecting white matter, and microcephaly. Secondary thinning of the corpus callosum can be caused by diffuse injury such as hypoxic-ischemic encephalopathy, human immunodeficiency virus (HIV) encephalopathy, hydrocephalus, dysmyelinating conditions and demyelinating conditions. Focal disturbance of formation or focal injury also causes localized thinning, e.g., callosal dysgenesis, metabolic disorders with localized effects, hypoglycemia, white matter injury of prematurity, HIV-related atrophy, infarction and vasculitis, trauma and toxins. The corpus callosum might be too thick because of a primary disorder in which the corpus callosum finding is essential to diagnosis; abnormal thickening can also be secondary to inflammation, infection and trauma. (orig.)

  14. 78 FR 19985 - Modification of VOR Federal Airways V-68, V-76, V-194, and V-548 in the Vicinity of Houston, TX

    Science.gov (United States)

    2013-04-03

    ..., and V-548 in the Vicinity of Houston, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... airways V-68, V-76, V-194, and V-548 in the vicinity of Houston, TX. The FAA is taking this action to... vicinity of Houston, TX. Specifically, the FAA amends V-68 and V-76 to reflect the Hobby VOR/DME 289[deg...

  15. English Collocation Learning through Corpus Data: On-Line Concordance and Statistical Information

    Science.gov (United States)

    Ohtake, Hiroshi; Fujita, Nobuyuki; Kawamoto, Takeshi; Morren, Brian; Ugawa, Yoshihiro; Kaneko, Shuji

    2012-01-01

    We developed an English Collocations On Demand system offering on-line corpus and concordance information to help Japanese researchers acquire a better command of English collocation patterns. The Life Science Dictionary Corpus consists of approximately 90,000,000 words collected from life science related research papers published in academic…

  16. Using Edit Distance to Analyse Errors in a Natural Language to Logic Translation Corpus

    Science.gov (United States)

    Barker-Plummer, Dave; Dale, Robert; Cox, Richard; Romanczuk, Alex

    2012-01-01

    We have assembled a large corpus of student submissions to an automatic grading system, where the subject matter involves the translation of natural language sentences into propositional logic. Of the 2.3 million translation instances in the corpus, 286,000 (approximately 12%) are categorized as being in error. We want to understand the nature of…

  17. Copy Number Variations Found in Patients with a Corpus Callosum Abnormality and Intellectual Disability.

    Science.gov (United States)

    Heide, Solveig; Keren, Boris; Billette de Villemeur, Thierry; Chantot-Bastaraud, Sandra; Depienne, Christel; Nava, Caroline; Mignot, Cyril; Jacquette, Aurélia; Fonteneau, Eric; Lejeune, Elodie; Mach, Corinne; Marey, Isabelle; Whalen, Sandra; Lacombe, Didier; Naudion, Sophie; Rooryck, Caroline; Toutain, Annick; Caignec, Cédric Le; Haye, Damien; Olivier-Faivre, Laurence; Masurel-Paulet, Alice; Thauvin-Robinet, Christel; Lesne, Fabien; Faudet, Anne; Ville, Dorothée; des Portes, Vincent; Sanlaville, Damien; Siffroi, Jean-Pierre; Moutard, Marie-Laure; Héron, Delphine

    2017-06-01

    To evaluate the role that chromosomal micro-rearrangements play in patients with both corpus callosum abnormality and intellectual disability, we analyzed copy number variations (CNVs) in patients with corpus callosum abnormality/intellectual disability STUDY DESIGN: We screened 149 patients with corpus callosum abnormality/intellectual disability using Illumina SNP arrays. In 20 patients (13%), we have identified at least 1 CNV that likely contributes to corpus callosum abnormality/intellectual disability phenotype. We confirmed that the most common rearrangement in corpus callosum abnormality/intellectual disability is inverted duplication with terminal deletion of the 8p chromosome (3.2%). In addition to the identification of known recurrent CNVs, such as deletions 6qter, 18q21 (including TCF4), 1q43q44, 17p13.3, 14q12, 3q13, 3p26, and 3q26 (including SOX2), our analysis allowed us to refine the 2 known critical regions associated with 8q21.1 deletion and 19p13.1 duplication relevant for corpus callosum abnormality; report a novel 10p12 deletion including ZEB1 recently implicated in corpus callosum abnormality with corneal dystrophy; and) report a novel pathogenic 7q36 duplication encompassing SHH. In addition, 66 variants of unknown significance were identified in 57 patients encompassed candidate genes. Our results confirm the relevance of using microarray analysis as first line test in patients with corpus callosum abnormality/intellectual disability. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Lexical Properties of Slovene Sign Language: A Corpus-Based Study

    Science.gov (United States)

    Vintar, Špela

    2015-01-01

    Slovene Sign Language (SZJ) has as yet received little attention from linguists. This article presents some basic facts about SZJ, its history, current status, and a description of the Slovene Sign Language Corpus and Pilot Grammar (SIGNOR) project, which compiled and annotated a representative corpus of SZJ. Finally, selected quantitative data…

  19. Microstructural changes in thickened corpus callosum in children: contribution of magnetic resonance diffusion tensor imaging

    Energy Technology Data Exchange (ETDEWEB)

    Merlini, Laura; Anooshiravani, Mehrak; Kanavaki, Aikaterini; Hanquinet, Sylviane [University of Geneva Children' s Hospital, Pediatric Radiology Unit, Geneva (Switzerland)

    2015-06-15

    Thickened corpus callosum is a rare finding and its pathophysiology is not well known. An anomalous supracallosal bundle has been depicted by fiber tracking in some cases but no diffusion tensor imaging metrics of thickened corpus callosum have been reported. To use diffusion tensor imaging (DTI) in cases of thickened corpus callosum to help in understanding its clinical significance. During a 7-year period five children (ages 6 months to 15 years) with thickened corpus callosum were studied. We determined DTI metrics of fractional anisotropy (FA), mean diffusivity, and axial (λ1) and radial (λ2, λ3) diffusivity and performed 3-D fiber tracking reconstruction of the thickened corpus callosum. We compared our results with data from the literature and 24 age-matched controls. Brain abnormalities were seen in all cases. All children had at least three measurements of corpus callosum thickness above the 97th percentile according to age. In all children 3-D fiber tracking showed an anomalous supracallosal bundle and statistically significant decrease in FA (P = 0.003) and λ1 (P = 0.001) of the corpus callosum compared with controls, but no significant difference in mean diffusivity and radial diffusivity. Thickened corpus callosum was associated with abnormal bundles, suggesting underlying axonal guidance abnormality. DTI metrics suggested abnormal fiber compactness and density, which may be associated with alterations in cognition. (orig.)

  20. The English Definite Article: What ESL/EFL Grammars Say and What Corpus Findings Show

    Science.gov (United States)

    WonHo Yoo, Isaiah

    2009-01-01

    To ascertain whether what ESL/EFL grammars say is informed by what scholars discuss in the literature and supported by what corpus findings actually show, this paper first presents a brief overview of the literature on the English definite article and then compares popular ESL/EFL grammars' coverage of "the" and corpus findings on definite article…

  1. US News Media Portrayal of Islam and Muslims: A Corpus-Assisted Critical Discourse Analysis

    Science.gov (United States)

    Samaie, Mahmoud; Malmir, Bahareh

    2017-01-01

    This article exploits the synergy of critical discourse studies and Corpus Linguistics to study the pervasive representation of Islam and Muslims in an approximate 670,000-word corpus of US news media stories published between 2001 and 2015. Following collocation and concordance analysis of the most frequent topics or categories which revolve…

  2. Corpus gastritis in patients with endoscopic diagnosis of reflux oesophagitis and Barrett's oesophagus.

    NARCIS (Netherlands)

    Laheij, R.J.F.; Rossum, L.G.M. van; Boer, W.A. de; Jansen, J.B.M.J.

    2002-01-01

    BACKGROUND: A high level of gastric acid secretion is considered to be a risk factor for reflux oesophagitis or Barrett's oesophagus. Corpus gastritis may have a protective effect on the oesophagus, because of decreased gastric acid output. AIM: To determine if corpus gastritis is associated with

  3. Applying Corpus-Based Findings to Form-Focused Instruction: The Case of Reported Speech

    Science.gov (United States)

    Barbieri, Federica; Eckhardt, Suzanne E. B.

    2007-01-01

    Arguing that the introduction of corpus linguistics in teaching materials and the language classroom should be informed by theories and principles of SLA, this paper presents a case study illustrating how corpus-based findings on reported speech can be integrated into a form-focused model of instruction. After overviewing previous work which…

  4. Corpus callosum tissue loss and development of motor and global cognitive impairment

    DEFF Research Database (Denmark)

    Frederiksen, Kristian S; Garde, Ellen; Skimminge, Arnold

    2011-01-01

    To examine the impact of corpus callosum (CC) tissue loss on the development of global cognitive and motor impairment in the elderly.......To examine the impact of corpus callosum (CC) tissue loss on the development of global cognitive and motor impairment in the elderly....

  5. An Analysis of Stative Verbs Used with the Progressive Aspect in Corpus-Informed Textbooks

    Science.gov (United States)

    Belli, Serap Atasever

    2018-01-01

    This study was designed to investigate whether contemporary corpus-informed grammar textbooks written for English language learners and teachers presented the progressive use of stative verbs and if yes, which stative verbs were presented to occur with the progressive aspect and for which functions they took this aspect. A corpus of six electronic…

  6. A Corpus-Based View of Lexical Gender in Written Business English

    Science.gov (United States)

    Fuertes-Olivera, Pedro A.

    2007-01-01

    This article investigates lexical gender in specialized communication. The key method of analysis is that of forms of address, professional titles, and "generic man" in a 10 million word corpus of written Business English. After a brief introduction and literature review on both gender in specialized communication and similar corpus-based views of…

  7. Incidence and lifetime risk of uterine corpus cancer in Taiwanese women from 1991 to 2010

    Directory of Open Access Journals (Sweden)

    Jerry Cheng-Yen Lai

    2017-02-01

    Conclusion: According to the observed changes in incidence rate, the burden of uterine corpus cancer in the general female population is expected to increase in the near future. From a public-health perspective, care providers should develop strategies for the prevention, early detection, and intervention to reduce the rapidly increasing incidence of uterine corpus cancer in Taiwan.

  8. Analysing Culture and Interculture in Saudi EFL Textbooks: A Corpus Linguistic Approach

    Science.gov (United States)

    Almujaiwel, Sultan

    2018-01-01

    This paper combines corpus processing tools to investigate the cultural elements of Saudi education of English as a foreign language (EFL). The latest Saudi EFL textbooks (2016 onwards) are available in researchable PDF formats. This helps process them through corpus search software tools. The method adopted is based on analysing 20 cultural…

  9. A 38 million words Dutch text corpus and its users | Kruyt | Lexikos

    African Journals Online (AJOL)

    In August 1996, the 38 Million Words Corpus was available for consultation by the international research community. The present paper reports on the characteristics of this corpus (design, text classification, linguistic annotation) and on its use, both in dictionary projects and in linguistic research. In spite of limitations with ...

  10. Binding sites and actions of Tx1, a neurotoxin from the venom of the spider Phoneutria nigriventer, in guinea pig ileum

    Directory of Open Access Journals (Sweden)

    R.G. Santos

    1999-12-01

    Full Text Available Tx1, a neurotoxin isolated from the venom of the South American spider Phoneutria nigriventer, produces tail elevation, behavioral excitation and spastic paralysis of the hind limbs after intracerebroventricular injection in mice. Since Tx1 contracts isolated guinea pig ileum, we have investigated the effect of this toxin on acetylcholine release, as well as its binding to myenteric plexus-longitudinal muscle membranes from the guinea pig ileum. [125I]-Tx1 binds specifically and with high affinity (Kd = 0.36 ± 0.02 nM to a single, non-interacting (nH = 1.1, low capacity (Bmax 1.1 pmol/mg protein binding site. In competition experiments using several compounds (including ion channel ligands, only PhTx2 and PhTx3 competed with [125I]-Tx1 for specific binding sites (K0.5 apparent = 7.50 x 10-4 g/l and 1.85 x 10-5 g/l, respectively. PhTx2 and PhTx3, fractions from P. nigriventer venom, contain toxins acting on sodium and calcium channels, respectively. However, the neurotoxin PhTx2-6, one of the isoforms found in the PhTx2 pool, did not affect [125I]-Tx1 binding. Tx1 reduced the [3H]-ACh release evoked by the PhTx2 pool by 33%, but did not affect basal or KCl-induced [3H]-ACh release. Based on these results, as well as on the homology of Tx1 with toxins acting on calcium channels (w-Aga IA and IB and its competition with [125I]-w-Cono GVIA in the central nervous system, we suggest that the target site for Tx1 may be calcium channels.

  11. Enculturating Conversational Agents based on a Comparative Corpus Study

    DEFF Research Database (Denmark)

    Lipi, Afia Akhter; Yamaoka, Yuji; Rehm, Matthias

    2008-01-01

    When encountering people who have a different cultural background from our own, many of us feel uncomfortable because gestures and facial expressions may not be familiar to us. Thus, to enhance the believability of conversational agents, culture-specific nonverbal behaviors should be implemented ...... a more detailed analysis about posture shifts, and proposes a chat system with an embodied conversational agent (ECA) that can act as a language trainer....... into the agents. In our previous study, with the goal of building a user interface that incorporates a user’s cultural background, we have collected comparative conversation corpus in Germany and Japan, and investigated the differences in gestures and posture shifts between these two countries. This paper reports...

  12. The Brazilian Theory of Habeas Corpus for Great Apes

    Directory of Open Access Journals (Sweden)

    Heron José de Santana Gordilho

    2016-06-01

    Full Text Available This essay presents a comparison between human evolution and legal developments, trying to demonstrate how darwinian theory of evolution by natural selection has caused changes in the legal world, the bridge of today some lawyers using the recent discoveries about how similar genetic between man and great primates to claim extension of human rights for chimpanzees, bonobos, gorillas and orangs. It also that many activists for animal`s rights have considered the dispute an important strategy, whether to set new means for legal institutes such as the Habeas Corpus, hitherto used only to ensure human freedom, whether to increase the movement and increase the conscietization of the general population about the importance of the recognition of animals as holders of basic rights.

  13. Some aspects of endotoxins and corpus luteum function in ruminants

    International Nuclear Information System (INIS)

    Edqvist, L.E.; Fredriksson, G.; Kindahl, H.

    1984-01-01

    Following parturition in cattle, prostaglandin levels are high for 10-20 days. The duration and possibly the magnitude of the release seem to be related to the time required for completion of uterine involution. Animals showing clinical signs of postpartum uterine disorder have a prolonged release of prostaglandin. The intravenous administration of an endotoxin from Salmonella typhimurium to goats induces a massive prostaglandin release terminating corpus luteum function, resulting in short oestrous cycles in non-pregnant animals and abortions in pregnant animals. The possibility exists that postpartum uterine infections may be partly responsible for the postpartum prostaglandin release and that this bacteriologic/endocrine interrelationship represents a way in which the uterus eliminates infectious agents, particularly gram-negative bacteria. (author)

  14. ANR Corpus architecturae religiosae europeae [CARE], saec. IV-X

    Directory of Open Access Journals (Sweden)

    Christian Sapin

    2008-07-01

    Full Text Available À la fin de l’année 2007, le projet déposé auprès de l’Agence nationale de la recherche (ANR et consacré à la constitution d’un corpus des monuments religieux (CARE antérieurs à l’an Mil a été retenu. Il correspond au volet propre à la France. En effet, plusieurs pays, dont l’Italie, l’Espagne, la République Tchèque, la Slovaquie, la Pologne et la Croatie ont commencé depuis deux ans les travaux préparatoires à cette ambitieuse entreprise ; la Grèce est, depuis, intéressée, de même que l’Al...

  15. Chemokines in the corpus luteum: Implications of leukocyte chemotaxis

    Directory of Open Access Journals (Sweden)

    Liptak Amy R

    2003-11-01

    Full Text Available Abstract Chemokines are small molecular weight peptides responsible for adhesion, activation, and recruitment of leukocytes into tissues. Leukocytes are thought to influence follicular atresia, ovulation, and luteal function. Many studies in recent years have focused attention on the characterization of leukocyte populations within the ovary, the importance of leukocyte-ovarian cell interactions, and more recently, the mechanisms of ovarian leukocyte recruitment. Information about the role of chemokines and leukocyte trafficking (chemotaxis during ovarian function is important to understanding paracrine-autocrine relationships shared between reproductive and immune systems. Recent advances regarding chemokine expression and leukocyte accumulation within the ovulatory follicle and the corpus luteum are the subject of this mini-review.

  16. Embedding epistemic modals in English: A corpus-based study

    Directory of Open Access Journals (Sweden)

    Valentine Hacquard

    2012-07-01

    Full Text Available The question of whether epistemic modals contribute to the truth conditions of the sentences they appear in is a matter of active debate in the literature. Fueling this debate is the lack of consensus about the extent to which epistemics can appear in the scope of other operators. This corpus study investigates the distribution of epistemics in naturalistic data. Our results indicate that they do embed, supporting the view that they contribute semantic content. However, their distribution is limited, compared to that of other modals. This limited distribution seems to call for a nuanced account: while epistemics are semantically contentful, they may require special licensing conditions. http://dx.doi.org/10.3765/sp.5.4 BibTeX info

  17. Murine Models of Gastric Corpus PreneoplasiaSummary

    Directory of Open Access Journals (Sweden)

    Christine P. Petersen

    2017-01-01

    Full Text Available Intestinal-type gastric adenocarcinoma evolves in a field of pre-existing metaplasia. Over the past 20 years, a number of murine models have been developed to address aspects of the physiology and pathophysiology of metaplasia induction. Although none of these models has achieved true recapitulation of the induction of adenocarcinoma, they have led to important insights into the factors that influence the induction and progression of metaplasia. Here, we review the pathologic definitions relevant to alterations in gastric corpus lineages and classification of metaplasia by specific lineage markers. In addition, we review present murine models of the induction and progression of spasmolytic polypeptide (TFF2–expressing metaplasia, the predominant metaplastic lineage observed in murine models. These models provide a basis for the development of a broader understanding of the physiological and pathophysiological roles of metaplasia in the stomach. Keywords: SPEM, Intestinal Metaplasia, Gastric Cancer, TFF2, Chief Cell, Hyperplasia

  18. The structure of an entry in the National corpus of Tuvan language

    Directory of Open Access Journals (Sweden)

    Mengi V. Ondar

    2016-12-01

    Full Text Available Contemporary information technologies and mathematical modelling has made creating corpora of natural languages significantly easier. A corpus is an information and reference system based on a collection of digitally processed texts. A corpus includes various written and oral texts in the given language, a set of dictionaries and markup – information on the properties of the text. It is the presence of the markup which distinguishes a corpus from an electronic library. At the moment, national corpora are being set up for many languages of the Russian Federation, including those of the Turkic peoples. Faculty members, postgraduate and undergraduate students at Tuvan State University and Siberian Federal University are working on the National corpus of Tuvan language. This article describes the structure of a dictionary entry in the National corpus of Tuvan language. The corpus database comprises the following tables: MAIN – the headword table, RUS, ENG, GER — translations of the headword into three languages, MORPHOLOGY — the table containing morphological data on the headword. The database is built in Microsoft Office Access. Working with the corpus dictionary includes the following functions: adding, editing and removing an entry, entry search (with transcription, setting and visualizing morphological features of a headword. The project allows us to view the corpus dictionary as a multi-structure entity with a complex hierarchical structure and a dictionary entry as its key component. The corpus dictionary we developed can be used for studying Tuvan language in its pronunciation, orthography and word analysis, as well as for searching for words and collocations in the texts included into the corpus.

  19. The Wildcat Corpus of Native- and Foreign-Accented English: Communicative Efficiency across Conversational Dyads with Varying Language Alignment Profiles

    Science.gov (United States)

    Van Engen, Kristin J.; Baese-Berk, Melissa; Baker, Rachel E.; Choi, Arim; Kim, Midam; Bradlow, Ann R.

    2010-01-01

    This paper describes the development of the Wildcat Corpus of native- and foreign-accented English, a corpus containing scripted and spontaneous speech recordings from 24 native speakers of American English and 52 non-native speakers of English. The core element of this corpus is a set of spontaneous speech recordings, for which a new method of…

  20. Determination of Disulfide Bond Connectivity of Cysteine-rich Peptide IpTx{sub a}

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chul Won; Kim, Jim Il [Chonnam National Univ., Gwangju (Korea, Republic of); Sato, Kazuki [Fukuoka Women' s Univ., Fukuoka (Japan)

    2013-06-15

    Cysteine-rich peptides stabilized by intramolecular disulfide bonds have often been isolated from venoms of microbes, animals and plants. These peptides typically have much higher stability and improved biopharmaceutical properties compared to their linear counterparts. Therefore the correct disulfide bond formation of small proteins and peptides has been extensively studied for a better understanding of their folding mechanism and achieving efficient generation of the naturally occurring biologically active product. Imperatoxin A (IpTx{sub a}), a peptide toxin containing 6 cysteine residues, was isolated from the venom of scorpion Pandinus imperator, selectively binds the ryanodine receptors and activates Ca{sup 2+} release from sarcoplasmic reticulum (SR). IpTx{sub a} increases the binding of ryanodine to ryanodine receptors (RyRs) and encourages reconstituted single channel to induce subconductance states.

  1. Energy Optimization Assessment at U.S. Army Installations: Fort Bliss, TX

    Science.gov (United States)

    2008-09-01

    Log dampers, temperatures, actuator signals, and other parameters to identify problems. Adjust chiller and boiler setpoints and control curves...installation. The lowest setpoints were found in the Centennial Club, with 52 °F during unoccupied hours (morn- ing). The chillers ran pretty much fully loaded...ER D C/ CE R L TR -0 8 -1 5 Energy Optimization Assessment at U.S. Army Installations Fort Bliss, TX David M. Underwood, Alexander M

  2. Biochemical, Pharmacological, and Structural Characterization of New Basic Bbil-TX from Bothriopsis bilineata Snake Venom

    Directory of Open Access Journals (Sweden)

    Victor Corasolla Carregari

    2013-01-01

    Full Text Available Bbil-TX, a PLA2, was purified from Bothriopsis bilineata snake venom after only one chromatographic step using RP-HPLC on μ-Bondapak C-18 column. A molecular mass of 14243.8 Da was confirmed by Q-Tof Ultima API ESI/MS (TOF MS mode mass spectrometry. The partial protein sequence obtained was then submitted to BLASTp, with the search restricted to PLA2 from snakes and shows high identity values when compared to other PLA2s. PLA2 activity was presented in the presence of a synthetic substrate and showed a minimum sigmoidal behavior, reaching its maximal activity at pH 8.0 and 25–37∘C. Maximum PLA2 activity required Ca2+ and in the presence of Cd2+, Zn2+, Mn2+, and Mg2+ it was reduced in the presence or absence of Ca2+. Crotapotin from Crotalus durissus cascavella rattlesnake venom and antihemorrhagic factor DA2-II from Didelphis albiventris opossum sera under optimal conditions significantly inhibit the enzymatic activity. Bbil-TX induces myonecrosis in mice. The fraction does not show a significant cytotoxic activity in myotubes and myoblasts (C2C12. The inflammatory events induced in the serum of mice by Bbil-TX isolated from Bothriopsis bilineata snake venom were investigated. An increase in vascular permeability and in the levels of TNF-a, IL-6, and IL-1 was was induced. Since Bbil-TX exerts a stronger proinflammatory effect, the phospholipid hydrolysis may be relevant for these phenomena.

  3. GOC-TX: A Reliable Ticket Synchronization Application for the Open Science Grid

    Science.gov (United States)

    Hayashi, Soichi; Gopu, Arvind; Quick, Robert

    2011-12-01

    One of the major operational issues faced by large multi-institutional collaborations is permitting its users and support staff to use their native ticket tracking environment while also exchanging these tickets with collaborators. After several failed attempts at email-parser based ticket exchanges, the OSG Operations Group has designed a comprehensive ticket synchronizing application. The GOC-TX application uses web-service interfaces offered by various commercial, open source and other homegrown ticketing systems, to synchronize tickets between two or more of these systems. GOC-TX operates independently from any ticketing system. It can be triggered by one ticketing system via email, active messaging, or a web-services call to check for current sync-status, pull applicable recent updates since prior synchronizations to the source ticket, and apply the updates to a destination ticket. The currently deployed production version of GOC-TX is able to synchronize tickets between the Numara Footprints ticketing system used by the OSG and the following systems: European Grid Initiative's system Global Grid User Support (GGUS) and the Request Tracker (RT) system used by Brookhaven. Additional interfaces to the BMC Remedy system used by Fermilab, and to other instances of RT used by other OSG partners, are expected to be completed in summer 2010. A fully configurable open source version is expected to be made available by early autumn 2010. This paper will cover the structure of the GOC-TX application, its evolution, and the problems encountered by OSG Operations group with ticket exchange within the OSG Collaboration.

  4. GOC-TX: A Reliable Ticket Synchronization Application for the Open Science Grid

    International Nuclear Information System (INIS)

    Hayashi, Soichi; Gopu, Arvind; Quick, Robert

    2011-01-01

    One of the major operational issues faced by large multi-institutional collaborations is permitting its users and support staff to use their native ticket tracking environment while also exchanging these tickets with collaborators. After several failed attempts at email-parser based ticket exchanges, the OSG Operations Group has designed a comprehensive ticket synchronizing application. The GOC-TX application uses web-service interfaces offered by various commercial, open source and other homegrown ticketing systems, to synchronize tickets between two or more of these systems. GOC-TX operates independently from any ticketing system. It can be triggered by one ticketing system via email, active messaging, or a web-services call to check for current sync-status, pull applicable recent updates since prior synchronizations to the source ticket, and apply the updates to a destination ticket. The currently deployed production version of GOC-TX is able to synchronize tickets between the Numara Footprints ticketing system used by the OSG and the following systems: European Grid Initiative's system Global Grid User Support (GGUS) and the Request Tracker (RT) system used by Brookhaven. Additional interfaces to the BMC Remedy system used by Fermilab, and to other instances of RT used by other OSG partners, are expected to be completed in summer 2010. A fully configurable open source version is expected to be made available by early autumn 2010. This paper will cover the structure of the GOC-TX application, its evolution, and the problems encountered by OSG Operations group with ticket exchange within the OSG Collaboration.

  5. Magnetic resonance findings of the corpus callosum in canine and feline lysosomal storage diseases.

    Science.gov (United States)

    Hasegawa, Daisuke; Tamura, Shinji; Nakamoto, Yuya; Matsuki, Naoaki; Takahashi, Kimimasa; Fujita, Michio; Uchida, Kazuyuki; Yamato, Osamu

    2013-01-01

    Several reports have described magnetic resonance (MR) findings in canine and feline lysosomal storage diseases such as gangliosidoses and neuronal ceroid lipofuscinosis. Although most of those studies described the signal intensities of white matter in the cerebrum, findings of the corpus callosum were not described in detail. A retrospective study was conducted on MR findings of the corpus callosum as well as the rostral commissure and the fornix in 18 cases of canine and feline lysosomal storage diseases. This included 6 Shiba Inu dogs and 2 domestic shorthair cats with GM1 gangliosidosis; 2 domestic shorthair cats, 2 familial toy poodles, and a golden retriever with GM2 gangliosidosis; and 2 border collies and 3 chihuahuas with neuronal ceroid lipofuscinoses, to determine whether changes of the corpus callosum is an imaging indicator of those diseases. The corpus callosum and the rostral commissure were difficult to recognize in all cases of juvenile-onset gangliosidoses (GM1 gangliosidosis in Shiba Inu dogs and domestic shorthair cats and GM2 gangliosidosis in domestic shorthair cats) and GM2 gangliosidosis in toy poodles with late juvenile-onset. In contrast, the corpus callosum and the rostral commissure were confirmed in cases of GM2 gangliosidosis in a golden retriever and canine neuronal ceroid lipofuscinoses with late juvenile- to early adult-onset, but were extremely thin. Abnormal findings of the corpus callosum on midline sagittal images may be a useful imaging indicator for suspecting lysosomal storage diseases, especially hypoplasia (underdevelopment) of the corpus callosum in juvenile-onset gangliosidoses.

  6. Quantification of structural changes in the corpus callosumin children with profound hypoxic-ischaemic brain injury

    Energy Technology Data Exchange (ETDEWEB)

    Stivaros, Stavros M. [Manchester Academic Health Science Centre, Academic Unit of Paediatric Radiology, Royal Manchester Children' s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester (United Kingdom); University of Manchester, Centre for Imaging Sciences, Institute of Population Health, Manchester (United Kingdom); Radon, Mark R. [The Walton Centre NHS Foundation Trust, Department of Neuroradiology, Liverpool (United Kingdom); Mileva, Reneta; Gledson, Ann; Keane, John A. [University of Manchester, School of Computer Science, Manchester (United Kingdom); Connolly, Daniel J.A.; Batty, Ruth [Sheffield Children' s Hospital NHS Foundation Trust, Department of Neuroradiology, Sheffield (United Kingdom); Cowell, Patricia E. [University of Sheffield, Department of Human Communication Sciences, Sheffield (United Kingdom); Hoggard, Nigel; Griffiths, Paul D. [University of Sheffield, Academic Unit of Radiology, Sheffield (United Kingdom); Wright, Neville B.; Tang, Vivian [Manchester Academic Health Science Centre, Academic Unit of Paediatric Radiology, Royal Manchester Children' s Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester (United Kingdom)

    2016-01-15

    Birth-related acute profound hypoxic-ischaemic brain injury has specific patterns of damage including the paracentral lobules. To test the hypothesis that there is anatomically coherent regional volume loss of the corpus callosum as a result of this hemispheric abnormality. Study subjects included 13 children with proven acute profound hypoxic-ischaemic brain injury and 13 children with developmental delay but no brain abnormalities. A computerised system divided the corpus callosum into 100 segments, measuring each width. Principal component analysis grouped the widths into contiguous anatomical regions. We conducted analysis of variance of corpus callosum widths as well as support vector machine stratification into patient groups. There was statistically significant narrowing of the mid-posterior body and genu of the corpus callosum in children with hypoxic-ischaemic brain injury. Support vector machine analysis yielded over 95% accuracy in patient group stratification using the corpus callosum centile widths. Focal volume loss is seen in the corpus callosum of children with hypoxic-ischaemic brain injury secondary to loss of commissural fibres arising in the paracentral lobules. Support vector machine stratification into the hypoxic-ischaemic brain injury group or the control group on the basis of corpus callosum width is highly accurate and points towards rapid clinical translation of this technique as a potential biomarker of hypoxic-ischaemic brain injury. (orig.)

  7. English Writing Teaching Model Dependent on Computer Network Corpus Drive Model

    Directory of Open Access Journals (Sweden)

    Shi Lei

    2018-03-01

    Full Text Available At present, the mainstream lexicalized English writing methods take only the corpus dependence between words into consideration, without introducing the corpus collocation and other issues. “Drive” is a relatively essential feature of words. And once the drive structure of a word is determined, it will be relatively clear what kinds of words to collocate with, hence the structure of the sentence can be derived relatively directly. In this paper, the English writing model that relies on the computer network corpus drive model is put forward. In this model, rich English corpus is introduced in the decomposition of the rules and the calculation of the probability, which includes not only the corpus dependence information, but also the drive structure and other corpus collocation information. Improved computer network corpus drive model is used to carry out the English writing teaching experiment. The experimental results show that the precision and the recall rate are 88.76% and 87.43%, respectively. The F value of the comprehensive index is improved by 6.65% compared with the Collins headword driven English modes of writing.

  8. Quantification of structural changes in the corpus callosumin children with profound hypoxic-ischaemic brain injury

    International Nuclear Information System (INIS)

    Stivaros, Stavros M.; Radon, Mark R.; Mileva, Reneta; Gledson, Ann; Keane, John A.; Connolly, Daniel J.A.; Batty, Ruth; Cowell, Patricia E.; Hoggard, Nigel; Griffiths, Paul D.; Wright, Neville B.; Tang, Vivian

    2016-01-01

    Birth-related acute profound hypoxic-ischaemic brain injury has specific patterns of damage including the paracentral lobules. To test the hypothesis that there is anatomically coherent regional volume loss of the corpus callosum as a result of this hemispheric abnormality. Study subjects included 13 children with proven acute profound hypoxic-ischaemic brain injury and 13 children with developmental delay but no brain abnormalities. A computerised system divided the corpus callosum into 100 segments, measuring each width. Principal component analysis grouped the widths into contiguous anatomical regions. We conducted analysis of variance of corpus callosum widths as well as support vector machine stratification into patient groups. There was statistically significant narrowing of the mid-posterior body and genu of the corpus callosum in children with hypoxic-ischaemic brain injury. Support vector machine analysis yielded over 95% accuracy in patient group stratification using the corpus callosum centile widths. Focal volume loss is seen in the corpus callosum of children with hypoxic-ischaemic brain injury secondary to loss of commissural fibres arising in the paracentral lobules. Support vector machine stratification into the hypoxic-ischaemic brain injury group or the control group on the basis of corpus callosum width is highly accurate and points towards rapid clinical translation of this technique as a potential biomarker of hypoxic-ischaemic brain injury. (orig.)

  9. Tx1, from Phoneutria nigriventer spider venom, interacts with dihydropyridine sensitive-calcium channels in GH3 cells

    International Nuclear Information System (INIS)

    Gouvea dos Santos, R.; Soares, M.A.; Pimenta, A.M.; De Lima, M.E.; ICB, UFMG, Belo Horizonte

    2006-01-01

    The aim of this work was to use the binding assay of tritiated-dihydropyridine and radioiodinated Tx1, isolated from the Phoneutria nigriventer venom, in order to show the presence of Ca v 1 calcium channels on pituitary tumour cell (GH3). We showed that GH3 cells have specific sites for 125 I-Tx1, which are sensitive to nifedipine (∼20%). Reverse competition assay with 3 H-PN200-110 (40% inhibition) and electrophysiological data (50% inhibition) suggest that Ca v 1 calcium channels are target sites for this toxin. To summarize, Tx1 binds to specific sites on GH3 cells and this interaction results in Ca v 1 calcium channel blockade. 3 H-PN200-110 and 125 I-Tx1 binding assays proved to be useful tools to show the presence of calcium channels on GH3 cells. (author)

  10. The MR findings of the corpus callosum of normal young volunteers

    International Nuclear Information System (INIS)

    Okamoto, Kouichirou; Ito, Jusuke; Tokiguchi, Susumu

    1990-01-01

    The size and shape of the corpus callosum of twenty seven normal young volunteers (age 18-31 years, 17 men and 10 women) were investigated using a superconducting high field (1.5 T) MRI unit. The length of the corpus callosum was 71.1±5.1 mm (mean±S.D.) and the height was 24.9±2.1 mm. The length ratio of the corpus callosum to the brain was 43.9±2.3% with the ratio of the height 25.0±2.3%. The callosal index (height/length) was 35.4±2.9%. The area of the corpus callosum in the midsagittal plane was 681.4±93.6 mm 2 (min. 563 mm 2 to max. 902 mm 2 ). We divided the corpus callosum into three segments: rostrum and genu; anterior and posterior trunks; splenium. Each part accounts for one third of the total area of the corpus callosum. The genu and splenium were generally equal in thickness. The minimal thickness of the trunk was 3 mm with the maximal one 9 mm. The posterior trunk was never thicker than the anterior one. The posterior part of the posterior trunk showed thinning and concavity in almost all cases. So-called impressio corporis callosi was observed in 12 cases (44.4%). Thirteen cases (48.1%) showed a shallow concave configuration at the anterior dorsal surface of the corpus callosum. Six cases of these were thought to be due to compression by the pericallosal artery. This finding was not detected in the posterior portion of the corpus callosum. This concavity was also seen in infants. The thinning of the posterior part of the posterior trunk was seen after the development of the splenium, but the concave configuration at the anterior dorsal surface of the corpus callosum may be encountered before the full development of the genu and splenium. (author)

  11. On immune responsiveness of the organism of patients with corpus uteri cancer

    International Nuclear Information System (INIS)

    Gorodilova, V.V.; Yatskovskaya, N.L.

    1978-01-01

    Studied were some immunological indices in patients with cancer of corpus uteri. An attempt was made to elucidate a possible dependence of immunological indices on the process propagation rate and treatment methods. Updated methods used for uteri corpus cancer treatment except for progestinotherapeutics promote the decrease of organism responsiveness. Radiation therapy applied with total therapeutic dose has especially pronounced immunodepressing effect. Progestine series preparations result in the differentiation effect on tumours in some patients with cancer of corpus uteri, which clinically manifests in decreasing the tumour and even complete elimination. Simultaneously immunological indices in such patients are improved

  12. Radiographic evaluation of 70 patients with absence of the corpus callosum

    International Nuclear Information System (INIS)

    Byrd, S.E.; Flannery, A.; Osborn, R.E.; Radkowski, M.A.; Naidich, T.P.; Bohan, T.P.

    1987-01-01

    Absence (agenesis) of the corpus callosum is one of the most common congenital malformations of the brain seen in the pediatric population. The authors used CT, MR imaging, or US to study 70 children with absence of the corpus callosum. Patients were divided into two groups; those with isolated absence of the corpus callosum, and those with other associated brain lesions. The associated brain lesions included interhemispheric arachnoid cyst, Dandy-Walker malformations, encephaloceles, and migrational disorders (heterotopias, schizencephaly, lissencaphaly, septo-optic dysplasia, lipoma, Chiari malformations, and holoprosenscephaly). The clinical presentations and radiologic findings are described

  13. Preparing an annotated gold standard corpus to share with extramural investigators for de-identification research.

    Science.gov (United States)

    Deleger, Louise; Lingren, Todd; Ni, Yizhao; Kaiser, Megan; Stoutenborough, Laura; Marsolo, Keith; Kouril, Michal; Molnar, Katalin; Solti, Imre

    2014-08-01

    The current study aims to fill the gap in available healthcare de-identification resources by creating a new sharable dataset with realistic Protected Health Information (PHI) without reducing the value of the data for de-identification research. By releasing the annotated gold standard corpus with Data Use Agreement we would like to encourage other Computational Linguists to experiment with our data and develop new machine learning models for de-identification. This paper describes: (1) the modifications required by the Institutional Review Board before sharing the de-identification gold standard corpus; (2) our efforts to keep the PHI as realistic as possible; (3) and the tests to show the effectiveness of these efforts in preserving the value of the modified data set for machine learning model development. In a previous study we built an original de-identification gold standard corpus annotated with true Protected Health Information (PHI) from 3503 randomly selected clinical notes for the 22 most frequent clinical note types of our institution. In the current study we modified the original gold standard corpus to make it suitable for external sharing by replacing HIPAA-specified PHI with newly generated realistic PHI. Finally, we evaluated the research value of this new dataset by comparing the performance of an existing published in-house de-identification system, when trained on the new de-identification gold standard corpus, with the performance of the same system, when trained on the original corpus. We assessed the potential benefits of using the new de-identification gold standard corpus to identify PHI in the i2b2 and PhysioNet datasets that were released by other groups for de-identification research. We also measured the effectiveness of the i2b2 and PhysioNet de-identification gold standard corpora in identifying PHI in our original clinical notes. Performance of the de-identification system using the new gold standard corpus as a training set was very

  14. Mechanosensitive enteric neurons in the guinea pig gastric corpus

    Directory of Open Access Journals (Sweden)

    Gemma eMazzuoli-Weber

    2015-11-01

    Full Text Available For long it was believed that a particular population of enteric neurons, referred to as intrinsic primary afferent neuron (IPANs, encodes mechanical stimulation. We recently proposed a new concept suggesting that there are in addition mechanosensitive enteric neurons (MEN that are multifunctional. Based on firing pattern MEN behaved as rapidly, slowly or ultra-slowly adapting RAMEN, SAMEN or USAMEN, respectively. We aimed to validate this concept in the myenteric plexus of the gastric corpus, a region where IPANs were not identified and existence of enteric sensory neurons was even questioned. The gastric corpus is characterized by a particularly dense extrinsic sensory innervation. Neuronal activity was recorded with voltage sensitive dye imaging after deformation of ganglia by compression (intraganglionic volume injection or von Fry hair or tension (ganglionic stretch. We demonstrated that 27% of the gastric neurons were MEN and responded to intraganglionic volume injection. Of these 73% were RAMEN, 25% SAMEN and 2% USAMEN with a firing frequency of 1.7 (1.1/ 2.2 Hz, 5.1 (2.2/7.7 Hz and of 5.4 (5.0/15.5 Hz, respectively. The responses were reproducible and stronger with increased stimulus strength. Even after adaptation another deformation evoked spike discharge again suggesting a resetting mode of the mechanoreceptors. All MEN received fast synaptic input. 55% of all MEN were cholinergic and 45% nitrergic. Responses in some MEN significantly decreased after perfusion of TTX, low Ca++/high Mg++ Krebs solution, capsaicin induced nerve defunctionalization and capsazepine indicating the involvement of TRPV1 expressing extrinsic mechanosensitive nerves. Half of gastric MEN responded to intraganglionic volume injection as well as to ganglionic stretch and 23% responded to stretch only. Tension-sensitive MEN were to a large proportion USAMEN (44%. In summary, we demonstrated for the first time compression and tension-sensitive MEN in the stomach

  15. Unmasking Snake Venom of Bothrops leucurus: Purification and Pharmacological and Structural Characterization of New PLA2 Bleu TX-III

    Science.gov (United States)

    Marangoni, Fábio André; Ponce-Soto, Luis Alberto; Marangoni, Sergio; Landucci, Elen Cristina Teizem

    2013-01-01

    Bleu TX-III was isolated from Bothrops leucurus snake venom on one-step analytical chromatography reverse phase HPLC, was homogeneous on SDS-PAGE, and was confirmed by Q-Tof Ultima API ESI/MS (TOF MS mode) mass spectrometry in 14243.8 Da. Multiple alignments of Bleu TX-III show high degree of homology with basic PLA2 myotoxins from other Bothrops venoms. Our studies on local and systemic myotoxicity “in vivo” reveal that Bleu TX-III is myotoxin with local but not systemic action due to the decrease in the plasmatic CK levels when Bleu TX-III is administrated by intravenous route in mice (dose 1 and 5 μg). And at a dose of 20 μg myotoxin behaves like a local and systemic action. Bleu TX-III induced moderate marked paw edema, evidencing the local increase in vascular permeability. The inflammatory events induced in the mice (I.M.) were investigated. The increase in the levels of IL-1, IL-6, and TNF-α was observed in the plasma. It is concluded that Bleu TX-III induces inflammatory events in this model. The enzymatic phospholipid hydrolysis may be relevant to these phenomena. Bothrops leucurus venom is still not extensively explored, and the knowledge of its toxins separately through the study of structure/function will contribute for a better understanding of its action mechanism. PMID:23509815

  16. Combined therapy of corpus carcinoma with special regard to radiotherapy

    International Nuclear Information System (INIS)

    Wilhelm, C.

    1980-01-01

    From 496 case reports of patients with a corpus carcinoma collected between 1970 and 1976, the clinical findings, separation into clinical stages and the various therapy forms were compiled and evaluated. As a mean age of 62.3 years, 56.9 per cent of patients reached an average five-year, recidivation-free survival periods. Metastases occurred in 19.1 per cent of all treated women, vaginal recidivations in 1.8 per cent. Particular attention was given to the side effects of radiation therapy and retarded harmful effects. In this connexion an increase in complications following treatment with newly introduced radiation qualities had to be recorded. 21.9 per cent of all radiation-treated patients differed side-effects, and in 11.7 per cent of all radiation-treated women retarded harmful effects were found. Owing to the experience collected meanwhile in radiotherapy with ultra-hard X-rays and to the use of computerized tomography establishing the adequate quantity of radiation, complications following radiation treatment are expected to occur less frequently in future. (orig./MG) [de

  17. Follicle vascularity coordinates corpus luteum blood flow and progesterone production.

    Science.gov (United States)

    de Tarso, S G S; Gastal, G D A; Bashir, S T; Gastal, M O; Apgar, G A; Gastal, E L

    2017-03-01

    Colour Doppler ultrasonography was used to compare the ability of preovulatory follicle (POF) blood flow and its dimensions to predict the size, blood flow and progesterone production capability of the subsequent corpus luteum (CL). Cows (n=30) were submitted to a synchronisation protocol. Follicles ≥7mm were measured and follicular wall blood flow evaluated every 12h for approximately 3.5 days until ovulation. After ovulation, cows were scanned daily for 8 days and similar parameters were evaluated for the CL. Blood samples were collected and plasma progesterone concentrations quantified. All parameters were positively correlated. Correlation values ranged from 0.26 to 0.74 on data normalised to ovulation and from 0.31 to 0.74 on data normalised to maximum values. Correlations between calculated ratios of both POF and CL in data normalised to ovulation and to maximum values ranged from moderate (0.57) to strong (0.87). Significant (Pprogesterone concentrations of the resultant CL. These findings indicate that follicle vascularity coordinates CL blood flow and progesterone production in synchronised beef cows.

  18. The open corpus challenge in eLearning

    Directory of Open Access Journals (Sweden)

    Mahantesh K. Pattanshetti

    2018-03-01

    Full Text Available Learning has transcended into a life-long endeavor in the information age. It is no longer restricted to confines of formal classrooms. Consequently, a student is not restricted to traditional learning resources like teachers, textbooks or printed content. Digital resources available on the Internet form a very significant component of self-learning. Copious volumes of learning resources without legal barriers to self-learning reside in digital repositories, educational institution portals and on numerous websites. Learners wishing to utilize the web for personalized learning are faced with a daunting array of content to wade through and select the suitable ones to fulfill his/her learning objectives. Therefore, it is not a question of availability; it is one of relevance and suitability. Typically, in addition to time constraints, learners lack the expertise to screen content for effective eLearning. Adaptive hypermedia systems (AHSs offer a path to harnessing this large volume of learning resources for personalized learning. This review paper provides a concise and coherent discussion about the evolution of AHSs along with the challenges that need to be addressed for effectively harnessing openly available educational resources referred to as open corpus resources (OCRs.

  19. Acute infarction of corpus callosum due to transient obstructive hydrocephalus.

    Science.gov (United States)

    Kaymakamzade, Bahar; Eker, Amber

    2016-01-01

    Acute ischemia of the corpus callosum (CC) is not a well-known feature in patients with acute hydrocephalus. Herein, we describe a case with acute CC infarction due to another rare entity; transient obstructive hydrocephalus. A 66-year-old male was admitted with sudden onset right-sided hemiparesia. CT demonstrated a hematoma on the left basal ganglia with extension to all ventricles. The following day, the patient's neurological status progressed to coma and developed bilateral pyramidal signs. MRI demonstrated obstructive hydrocephalus and acute diffuse infarction accompanied by elevation of the CC. On the same day there was improvement in his neurological status with significant decrease in ventricular size and complete resolution of the clot in the third ventricle. The mechanism of signal abnormalities is probably related with the neural compression of the CC against the falx. Presumably, the clot causing obstruction in the third ventricle dissolved or decayed by the help of fibrinolytic activity of CSF, which was raised after IVH and caused spontaneous improvement of hydrocephalus. Bilateral neurological symptoms suggest diffuse axonal damage and normalization of the intracranial pressure should be performed on the early onset of clinical detorioration in order to prevent axonal injury. Copyright © 2016 Polish Neurological Society. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

  20. Parametric Probability Distribution Functions for Axon Diameters of Corpus Callosum

    Directory of Open Access Journals (Sweden)

    Farshid eSepehrband

    2016-05-01

    Full Text Available Axon diameter is an important neuroanatomical characteristic of the nervous system that alters in the course of neurological disorders such as multiple sclerosis. Axon diameters vary, even within a fiber bundle, and are not normally distributed. An accurate distribution function is therefore beneficial, either to describe axon diameters that are obtained from a direct measurement technique (e.g., microscopy, or to infer them indirectly (e.g., using diffusion-weighted MRI. The gamma distribution is a common choice for this purpose (particularly for the inferential approach because it resembles the distribution profile of measured axon diameters which has been consistently shown to be non-negative and right-skewed. In this study we compared a wide range of parametric probability distribution functions against empirical data obtained from electron microscopy images. We observed that the gamma distribution fails to accurately describe the main characteristics of the axon diameter distribution, such as location and scale of the mode and the profile of distribution tails. We also found that the generalized extreme value distribution consistently fitted the measured distribution better than other distribution functions. This suggests that there may be distinct subpopulations of axons in the corpus callosum, each with their own distribution profiles. In addition, we observed that several other distributions outperformed the gamma distribution, yet had the same number of unknown parameters; these were the inverse Gaussian, log normal, log logistic and Birnbaum-Saunders distributions.

  1. LINGUISTIC TEMPORALITY IN THE DIACHRONIC PERSPECTIVE: CORPUS ASPECT

    Directory of Open Access Journals (Sweden)

    Konnova Mariya Nikolaevna

    2014-06-01

    Full Text Available In the scope of complex cognitive and linguoculturological approach, aiming at investigating the triple unity of language, mind and culture, the author analyzes cognitive mechanisms of change in the meaning of New Testament saying "Dovleet dnevi zloba yego" (Mf. 6: 34 / "Sufficient for the day is the evil thereof" (St. Matthew 6: 34. This approach provides deeper insight into the essence of mental schemes underlying the process of lexicalisation of biblical micro-texts both as fixed phrases (quotations and idioms. The semantic shifts of microdiachronic character, which touched upon the semantic structure of biblical idiomatic expressions in 19-20th centuries and led to substantial restructuring of axiological and temporal components of meaning, are analyzed on the data of Russian National Corpus. The author proves that the use of biblical quotations outside their original context leads to their complete semantic transformation. The loss of original meaning is connected with the loss of key axiological and temporal characteristics typical for New Testament texts.

  2. Automated measurement of the human corpus callosum using MRI

    Directory of Open Access Journals (Sweden)

    Timothy J Herron

    2012-09-01

    Full Text Available The corpus callosum includes the majority of fibers that connect the two cortical hemispheres. Studies of cross-sectional callosal morphometry and area have revealed developmental, gender, and hemispheric differences in healthy populations and callosal deficits associated with neurodegenerative disease and brain injury. However, accurate quantification of the callosum using magnetic resonance imaging is complicated by intersubject variability in callosal size, shape, and location and often requires manual outlining of the callosum in order to achieve adequate performance. Here we describe an objective, fully automated protocol that utilizes voxel-based image to quantify the area and thickness both of the entire callosum and of different callosal compartments. We verify the method’s accuracy, reliability, robustness and multisite consistency and make comparisons with manual measurements using public brain-image databases. An analysis of age-related changes in the callosum showed increases in length and reductions in thickness and area with age. A comparison of older subjects with and without mild dementia revealed that reductions in anterior callosal area independently predicted poorer cognitive performance after factoring out Mini-Mental Status Examination scores and normalized whole brain volume. Open-source software implementing the algorithm is available at www.nitrc.org/projects/c8c8.

  3. Conjunctions in ELF academic discourse: a corpus-based analysis

    Directory of Open Access Journals (Sweden)

    Laura Centonze

    2014-03-01

    Full Text Available Abstract – Conjunctions as fundamental elements in the construction of discourse cohesion represent a relatively neglected research area, due to their complexity and the bewildering number of “conjunctive relations” (Halliday and Hasan 1976: 226 that they may express in context, as also highlighted in Christiansen (2011. In addition to this, there does not seem to be a shared view as far as the classification and denomination of the different kinds of conjunctions are concerned (cf. Halliday and Hasan 1976; Vande Kopple 1985; Martin and Rose 2003; Hyland 2005b. The selection of a specific type of conjunction acquires more importance because they are typically open to so many different interpretations, especially when the participants in the speech event come from diverse lingua-cultural backgrounds (cf. Guido 2007; Guido 2008; Cogo et al. 2011.Following the taxonomy provided by Halliday and Hasan (1976 for conjunctions, our study attempts to shed light on the usage of conjunctions by ELF speakers in specific contexts. We shall consider ten transcripts taken from the VOICE Corpus (Seidlhofer et. al 2013, namely five interviews and five conversations in multicultural academic contexts (approximately 4,000 words each, and analyze the number of instances for each type of conjunction (additive, adversative, clausal, temporal as well as continuatives in depth, by adopting a quantitative as well as a qualitative method and by using TextSTAT 2.9 (Huning 2012. We shall then move on to the analysis of conjunctions with respect to their internal properties/collocates and eventually see the occurrence of conjunctions by comparing them with the two different speech events which are chosen as the subject of our study, i.e. interviews and conversations. We shall see the extent to which certain conjunctions are more restricted than others in terms of usage (cf. Leung 2005 in both types of speech events, despite the great number of options available to the

  4. Penile fracture: MRI demonstration of a urethral tear associated with a rupture of the corpus cavernosum

    International Nuclear Information System (INIS)

    Maubon, A.J.; Roux, J.O.; Ferru, J.M.; Rouanet, J.P.; Faix, A.; Segui, B.

    1998-01-01

    We report a case of traumatic urethral tear associated with a rupture of the corpus cavernosum, demonstrated on MRI. We discuss the potential role of a non-invasive preoperative assessment by MRI. (orig.)

  5. The WONP-NURT corpus as nuclear knowledge base for text mining in the INIS database

    International Nuclear Information System (INIS)

    Guerra Valdes, R.

    2011-01-01

    In the present work the WONP-NURT corpus is taken as knowledge base for text mining in the INIS database. Main components of the information processing system, as well as computational methods for content analysis of INIS database record files are described. Results of the content analysis of the WONP-NURT corpus are reported. Furthermore, results of two comparative text mining studies in the INIS database are also shown. The first one explores 10 research areas in the more familiar nearest range of WONP-NURT corpus, while the second one surveys 15 regions in the more exotic far range. The results provide new elements to asses the significance of the WONP-NURT corpus in the context of the current state of nuclear science and technology research areas. (Author)

  6. Perceptual evaluation of corpus-based speech synthesis techniques in under-resourced environments

    CSIR Research Space (South Africa)

    Van Niekerk, DR

    2009-11-01

    Full Text Available With the increasing prominence and maturity of corpus-based techniques for speech synthesis, the process of system development has in some ways been simplified considerably. However, the dependence on sufficient amounts of relevant speech data...

  7. Form of the male and female corpus callosum internal organization at the mature age

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    Юрий Петрович Костиленко

    2016-04-01

    Full Text Available Aim: to study the special features of the male and female corpus callosum internal organization at the mature age.Materials and methods: the total preparations of the male and female corpus callosum (10 preparation of each sex at 45–60 years old were used as the material. The given preparations were used to get from it the plate cuts in the two mutually perpendicular planes with 2 mm. thick. Then the received tissue plates of the corpus callosum underwent plastination in the epoxy. Then the preparations were extracted from the non-polymerized epoxy and placed on the polyethylene film that was covered with the other film of the same size. Further this stratified block was placed amid the two glasses of the equal size that shrunk together by placing the small load on it. After the complete polymerization the received epoxy plates with the corpus callosum tissue contained in it underwent the gentle grinding and the accurate polish and as the result was obtained the surface denudation of its tissue structures that were colored with the 1 % solution of blue methylene for 1% borax solution.Results of research: at the study of the corpus callosum plastinated cuts in saggital plane was revealed that the transverse platen-form elevations of its higher surface are the cord-form tenias standing out from within and going through the corpus callosum. At its studying in the transverse cut was established that in adults can be separated two types of corpus callosum by its density: the dense one and disperse one.At the large increases of the binocular loupe (microscope MBS-9 can be seen the gaps between the adjacent commissural cords. Within it can be detected the blood vessels. On the transverse cut of commissural cords in its depth are revealed the thinnest streaks which totality consists of the two alternate dark and light lines that form the layered striation. Among the series of the light lines are visible the interlayer that separate the whole depth of

  8. Publishing a Quality Context-aware Annotated Corpus and Lexicon for Harassment Research

    OpenAIRE

    Rezvan, Mohammadreza; Shekarpour, Saeedeh; Balasuriya, Lakshika; Thirunarayan, Krishnaprasad; Shalin, Valerie; Sheth, Amit

    2018-01-01

    Having a quality annotated corpus is essential especially for applied research. Despite the recent focus of Web science community on researching about cyberbullying, the community dose not still have standard benchmarks. In this paper, we publish first, a quality annotated corpus and second, an offensive words lexicon capturing different types type of harassment as (i) sexual harassment, (ii) racial harassment, (iii) appearance-related harassment, (iv) intellectual harassment, and (v) politic...

  9. Determination of indices of the corpus callosum associated with normal aging in Japanese individuals

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, S.; Hirashima, Y.; Ikeda, H.; Yamamoto, H.; Endo, S. [Department of Neurosurgery, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama-shi, 930-0194, Toyama (Japan); Sugino, M. [Department of Neurosurgery, Sugino Hospital, Sengoku-cho 6-3-3, 930-0066, Toyama (Japan)

    2003-08-01

    Indices of the corpus callosum with normal aging and their sex differences were elucidated using quantitative MRI. We studied 94 Japanese men (mean{+-}SD 57.3{+-}20.8 years, range 6-90 years) and 111 Japanese women (mean{+-}SD 61.2{+-}17.6 years, range 9-86 years) who had no intracranial lesions on MRI and no history of neurological illness. The widths of the rostrum, body and splenium, the anterior to posterior length, and the maximum height in the midsagittal image were selected for measurement. The Evans index, which is the relative ratio of lateral ventricle expansion, and the maximum width of the third ventricle in the axial image were also estimated for comparison. The widths of rostrum, body and splenium of the corpus callosum became thinner with age. Conversely, the anterior to posterior length and the maximum height of the corpus callosum increased with age. The ratio of the width of the body to the length of the corpus callosum and the ratio of the width of the body to the height of the corpus callosum are best correlated with age. No sex differences in regional size of corpus callosum, including these two ratios, were observed in any raw measures, although ventricular indices were larger in men than women. Evaluation of the ratio of the width of the body to its length and the ratio of the width of the body to its height may enable accurate estimation of normal or pathological changes of the corpus callosum. Aging and pathological atrophy of corpus callosum can be evaluated without any adjustment for gender. (orig.)

  10. Determination of indices of the corpus callosum associated with normal aging in Japanese individuals

    International Nuclear Information System (INIS)

    Takeda, S.; Hirashima, Y.; Ikeda, H.; Yamamoto, H.; Endo, S.; Sugino, M.

    2003-01-01

    Indices of the corpus callosum with normal aging and their sex differences were elucidated using quantitative MRI. We studied 94 Japanese men (mean±SD 57.3±20.8 years, range 6-90 years) and 111 Japanese women (mean±SD 61.2±17.6 years, range 9-86 years) who had no intracranial lesions on MRI and no history of neurological illness. The widths of the rostrum, body and splenium, the anterior to posterior length, and the maximum height in the midsagittal image were selected for measurement. The Evans index, which is the relative ratio of lateral ventricle expansion, and the maximum width of the third ventricle in the axial image were also estimated for comparison. The widths of rostrum, body and splenium of the corpus callosum became thinner with age. Conversely, the anterior to posterior length and the maximum height of the corpus callosum increased with age. The ratio of the width of the body to the length of the corpus callosum and the ratio of the width of the body to the height of the corpus callosum are best correlated with age. No sex differences in regional size of corpus callosum, including these two ratios, were observed in any raw measures, although ventricular indices were larger in men than women. Evaluation of the ratio of the width of the body to its length and the ratio of the width of the body to its height may enable accurate estimation of normal or pathological changes of the corpus callosum. Aging and pathological atrophy of corpus callosum can be evaluated without any adjustment for gender. (orig.)

  11. Peptide LyeTx I mnΔk: A potential antimicrobial agent

    International Nuclear Information System (INIS)

    Fuscaldi, Leonardo Lima; Avelar Júnior, Joaquim T. de; Boff, Daiane; Santos, Daniel M. dos; Oliveira, Vívian L.S. de; Mata, Lays M. da; Contarini, Sara M. Lopes; Miranda, Sued E. Mendes; Amaral, Flavio Almeida; Diniz, Simone O.F.; Lima, Maria Elena de; Cardoso, Valbert N.

    2017-01-01

    Full text: Introduction: The emergence of resistance to current antibiotics and the incidence of opportunistic bacterial infections have stimulated the search for new antibiotic agents. In this sense, antimicrobial peptides are promising molecules due to their different mechanisms of action compared to classic antibiotics. Peptides LyeTx I (Lycosa erythrognatha venom) and LyeTx I mnΔK (truncated and modified derivative) present in vitro antimicrobial activity. Aim: To evaluate in vivo antimicrobial activity of LyeTx I mnΔK in an experimental model of septic arthritis. Methods: CEUA/UFMG: protocol nº 236/2014. At day 0, male C57/BL6 mice (∼7 weeks; (∼25 g) were inoculated with 10 μL of a S. aureus (ATCC® 6538) suspension (8 x 107 CFU/mL) or of sterile PBS (negative control group) by intraarticular injection (i.a.) in the right posterior articulation. At days 2, 4 and 6, mice were treated, by i.a., with clindamycin, LyeTx I or LyeTx I mnΔK (7.35, 0.08, 0.08 nmol/i.a., respectively). The positive control group received saline as treatment. At day 2 (before the first dose) and at day 7, an aliquot containing 7.4 MBq of technetium- 99m -Ceftizoxime ( 99m Tc-CFT) was injected into the tail vein of mice. At 2 h postradiopharmaceutical injection, animals were anesthetized and placed under a gamma camera (NuclideTM TH 22). Images were acquired during 5 min and quantitative analyzed to determine 99m Tc-CFT uptake by infectious focus, by means of target to non-target ratio (t/n-t) determination. Beyond scintigraphic images, animals were conducted to some other investigations post-treatment (at day 7). First, bacterial recovery assay was performed in order to assess pathogen reduction in the infected joint. Then, inflammatory process reduction was evaluated by the determination of immune cells recruitment. Finally, the removal threshold hypernociception was measured aiming to estimate pain. Quantitative data were expressed as 'mean±error' (n=4-6) and

  12. Peptide LyeTx I mnΔk: A potential antimicrobial agent

    Energy Technology Data Exchange (ETDEWEB)

    Fuscaldi, Leonardo Lima; Avelar Júnior, Joaquim T. de; Boff, Daiane; Santos, Daniel M. dos; Oliveira, Vívian L.S. de; Mata, Lays M. da; Contarini, Sara M. Lopes; Miranda, Sued E. Mendes; Amaral, Flavio Almeida; Diniz, Simone O.F.; Lima, Maria Elena de; Cardoso, Valbert N. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil)

    2017-07-01

    Full text: Introduction: The emergence of resistance to current antibiotics and the incidence of opportunistic bacterial infections have stimulated the search for new antibiotic agents. In this sense, antimicrobial peptides are promising molecules due to their different mechanisms of action compared to classic antibiotics. Peptides LyeTx I (Lycosa erythrognatha venom) and LyeTx I mnΔK (truncated and modified derivative) present in vitro antimicrobial activity. Aim: To evaluate in vivo antimicrobial activity of LyeTx I mnΔK in an experimental model of septic arthritis. Methods: CEUA/UFMG: protocol nº 236/2014. At day 0, male C57/BL6 mice (∼7 weeks; (∼25 g) were inoculated with 10 μL of a S. aureus (ATCC® 6538) suspension (8 x 107 CFU/mL) or of sterile PBS (negative control group) by intraarticular injection (i.a.) in the right posterior articulation. At days 2, 4 and 6, mice were treated, by i.a., with clindamycin, LyeTx I or LyeTx I mnΔK (7.35, 0.08, 0.08 nmol/i.a., respectively). The positive control group received saline as treatment. At day 2 (before the first dose) and at day 7, an aliquot containing 7.4 MBq of technetium-{sup 99m}-Ceftizoxime ({sup 99m}Tc-CFT) was injected into the tail vein of mice. At 2 h postradiopharmaceutical injection, animals were anesthetized and placed under a gamma camera (NuclideTM TH 22). Images were acquired during 5 min and quantitative analyzed to determine {sup 99m}Tc-CFT uptake by infectious focus, by means of target to non-target ratio (t/n-t) determination. Beyond scintigraphic images, animals were conducted to some other investigations post-treatment (at day 7). First, bacterial recovery assay was performed in order to assess pathogen reduction in the infected joint. Then, inflammatory process reduction was evaluated by the determination of immune cells recruitment. Finally, the removal threshold hypernociception was measured aiming to estimate pain. Quantitative data were expressed as 'mean±error' (n=4

  13. Textual, Genre and Social Features of Spoken Grammar: A Corpus-Based Approach

    Directory of Open Access Journals (Sweden)

    Carmen Pérez-Llantada

    2009-02-01

    Full Text Available This paper describes a corpus-based approach to teaching and learning spoken grammar for English for Academic Purposes with reference to Bhatia’s (2002 multi-perspective model for discourse analysis: a textual perspective, a genre perspective and a social perspective. From a textual perspective, corpus-informed instruction helps students identify grammar items through statistical frequencies, collocational patterns, context-sensitive meanings and discoursal uses of words. From a genre perspective, corpus observation provides students with exposure to recurrent lexico-grammatical patterns across different academic text types (genres. From a social perspective, corpus models can be used to raise learners’ awareness of how speakers’ different discourse roles, discourse privileges and power statuses are enacted in their grammar choices. The paper describes corpus-based instructional procedures, gives samples of learners’ linguistic output, and provides comments on the students’ response to this method of instruction. Data resulting from the assessment process and student production suggest that corpus-informed instruction grounded in Bhatia’s multi-perspective model can constitute a pedagogical approach in order to i obtain positive student responses from input and authentic samples of grammar use, ii help students identify and understand the textual, genre and social aspects of grammar in real contexts of use, and therefore iii help develop students’ ability to use grammar accurately and appropriately.

  14. Neural analysis of bovine ovaries ultrasound images in the identification process of the corpus luteum

    Science.gov (United States)

    Górna, K.; Jaśkowski, B. M.; Okoń, P.; Czechlowski, M.; Koszela, K.; Zaborowicz, M.; Idziaszek, P.

    2017-07-01

    The aim of the paper is to shown the neural image analysis as a method useful for identifying the development stage of the domestic bovine corpus luteum on digital USG (UltraSonoGraphy) images. Corpus luteum (CL) is a transient endocrine gland that develops after ovulation from the follicle secretory cells. The aim of CL is the production of progesterone, which regulates many reproductive functions. In the presented studies, identification of the corpus luteum was carried out on the basis of information contained in ultrasound digital images. Development stage of the corpus luteum was considered in two aspects: just before and middle of domination phase and luteolysis and degradation phase. Prior to the classification, the ultrasound images have been processed using a GLCM (Gray Level Co-occurence Matrix). To generate a classification model, a Neural Networks module implemented in the STATISTICA was used. Five representative parameters describing the ultrasound image were used as learner variables. On the output of the artificial neural network was generated information about the development stage of the corpus luteum. Results of this study indicate that neural image analysis combined with GLCM texture analysis may be a useful tool for identifying the bovine corpus luteum in the context of its development phase. Best-generated artificial neural network model was the structure of MLP (Multi Layer Perceptron) 5:5-17-1:1.

  15. An odd couple – Corpus frequency and look-up frequency: what relationship?

    Directory of Open Access Journals (Sweden)

    Lars Trap-Jensen

    2014-12-01

    Full Text Available In this paper, we investigate the relationship between log file records and corpus frequency. The study was motivated by practical considerations of how best to keep an already existing corpus-based dictionary updated. Should the next word in the dictionary be the one that follows next on a list of declining corpus frequency? Or the one that users most frequently look up but don’t find? In order to establish manageable criteria, we analysed log files for The Danish Dictionary from 2009 to 2012 and compared the list of most popular words looked up by the users with the frequency of the same words in the corpus underlying The Danish Dictionary. The users’ actual search behaviour was analysed in order to find answers to questions such as these: Are there words which are never looked up? If so, can we say something meaningful about their corpus frequency patterns – do they belong to particular parts of speech, are they particularly frequent or infrequent, could it even be that the pattern is cumulative, in such a way that a particular threshold can be identified? Ultimately, the question is whether it makes sense to use corpus frequency as a criterion for lemma selection.

  16. Segmentation of corpus callosum using diffusion tensor imaging: validation in patients with glioblastoma

    International Nuclear Information System (INIS)

    Nazem-Zadeh, Mohammad-Reza; Saksena, Sona; Babajani-Fermi, Abbas; Jiang, Quan; Soltanian-Zadeh, Hamid; Rosenblum, Mark; Mikkelsen, Tom; Jain, Rajan

    2012-01-01

    This paper presents a three-dimensional (3D) method for segmenting corpus callosum in normal subjects and brain cancer patients with glioblastoma. Nineteen patients with histologically confirmed treatment naïve glioblastoma and eleven normal control subjects underwent DTI on a 3T scanner. Based on the information inherent in diffusion tensors, a similarity measure was proposed and used in the proposed algorithm. In this algorithm, diffusion pattern of corpus callosum was used as prior information. Subsequently, corpus callosum was automatically divided into Witelson subdivisions. We simulated the potential rotation of corpus callosum under tumor pressure and studied the reproducibility of the proposed segmentation method in such cases. Dice coefficients, estimated to compare automatic and manual segmentation results for Witelson subdivisions, ranged from 94% to 98% for control subjects and from 81% to 95% for tumor patients, illustrating closeness of automatic and manual segmentations. Studying the effect of corpus callosum rotation by different Euler angles showed that although segmentation results were more sensitive to azimuth and elevation than skew, rotations caused by brain tumors do not have major effects on the segmentation results. The proposed method and similarity measure segment corpus callosum by propagating a hyper-surface inside the structure (resulting in high sensitivity), without penetrating into neighboring fiber bundles (resulting in high specificity)

  17. Trans-arterial xenotransplantation (Tx) of newborn porcine islet (NPI). A clinic trial for type I diabetes

    International Nuclear Information System (INIS)

    Wang Wei; Mo Zhaohui; Huang Zufa; Luo Xianming; Liu Sheng; Ye Bin; Li Bing; Liu Yingxin

    2002-01-01

    Objective: Liver is an important site to host transplanted islets, and implanting of islets by hepatic artery is simpler than by portal vein. Authors' study evaluated efficiency of the method and possible complication in a clinical setting. Methods: From October 1998 to June 2000, 4 type I diabetic patients received 4 x 10 6 (2 cases) and 8 x 10 6 (2 cases) of NPI through hepatic artery. Before Tx, all cases had the history with ketosis and acidosis. Exogenous insulin doses used for these cases were 25-48 units and their GHb was 9%-11%. After Tx, the NPI recipients were treated with immunosuppressants including cyclosporin 8 mg/kg for 12 months, cellcept 2 g/d for 25 days, and methylprednisolone 500 mg at 1 st day, then reduced to 50 mg for 3 days until to 10 mg for 1 month. Liver function and CD4/CD8 of the recipients were measured before and after Tx. Results: After Tx, the dose of exogenous insulin was increased to 60 mg due to methylprednisolone treatment. When methylprednisolone dose was decreased, the requirement for insulin was reduced to 32%-58% of the dose used before Tx. The reduction of required insulin for NPI recipients was proportional to the number of implanted NPI. In addition, GHb was also reduced to normal level (4%-6%) 3 months after Tx. No significant alterations of liver function and CD4 and CD8 in blood were observed after Tx. Conclusion: Trans-arterial intro-hepatic xenotransplantation of NPI is an efficient and safe therapeutic method for type I diabetes. Combination of cyclosporin, cellcept, and methylprednisolone is an effective immunosuppressive strategy for NPI xenograft transplantation

  18. Corpus-based Transitivity Biases in Individuals with Aphasia

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    Gayle DeDe

    2015-04-01

    Full Text Available Introduction Spontaneous speech samples in individuals with aphasia (IWA have been analyzed to examine many different psycholinguistic features. The present study focused on how IWA use verbs in spontaneous speech. Some verbs can occur in more than one argument structure, but are biased to occur more frequently in one frame than another. For example, "watch" appears in transitive and intransitive structures, but is usually used transitively. This is known as a transitivity bias. It is unknown whether IWA show the same transitivity biases in production as those reported in previous corpus studies with unimpaired individuals. Studies of sentence comprehension have shown that IWA are sensitive to verb biases (e.g., DeDe, 2013. In addition, IWA have shown an overall preference for transitive structures, which are the most frequent structures in English (Roland, Dick, & Elman, 2007. The present study investigated whether IWA show the same pattern of transitive and intransitive biases in spontaneous speech as unimpaired individuals. Method Participants: 278 interviews with IWA were taken from AphasiaBank. The IWA represented a range of aphasia types. Participants were omitted if they spoke English as a second language. Materials: 54 verbs were coded. We chose verbs with the goal of representing different bias types (e.g., transitive, intransitive, sentential complement. Of these, data from 11 transitively biased and 11 intransitively biased verbs (matched for frequency of use and number of syllables are presented here. Coding: All productions of the 54 verbs were coded. The coding protocol was based on Gahl, Jurafsky, and Roland (2004. We implemented an additional level of coding to indicate erroneous verb productions, such as ungrammatical structures and verb agreement errors. Results The (intransitivity biases for IWA were compared to biases from a previously published corpus study (Gahl et al., 2004. The IWA used transitively biased verbs in

  19. The Effect of Alcohol Administration on the Corpus Cavernosum

    Directory of Open Access Journals (Sweden)

    See Min Choi

    2017-04-01

    Full Text Available Purpose: We studied the effects of alcohol administration on the corpus cavernosum (CC using an animal model. Materials and Methods: CC sections and the aortic ring of rabbits were used in an organ bath study. After acute alcohol administration, changes in blood alcohol concentration and electrical stimulation induced intracavernosal pressure/mean arterial pressure (ICP/MAP percentage were compared in rats. Cyclic adenosine monophosphate (cAMP and cyclic guanosine monophosphate (cGMP levels in the CC were measured using immunoassays. After chronic alcohol administration, ICP/MAP percentage, cAMP and cGMP were compared in rats. Histological changes were examined using the Masson trichrome stain and the Sircol collagen assay. Endothelial nitric oxide synthase (eNOS expression was examined using immunohistochemistry and Western blotting. Results: Alcohol relaxed the CC in a dose-dependent manner, and the relaxation response was suppressed when pretreated with propranolol, indomethacin, glibenclamide, and 4-aminopyridine. In rats with acute alcohol exposure, the cAMP level in the CC was significantly greater than was observed in the control group (p<0.05. In rats with chronic alcohol exposure, however, changes in cAMP and cGMP levels were insignificant, and the CC showed markedly smaller areas of smooth muscle, greater amounts of dense collagen (p<0.05. Immunohistochemical analysis of eNOS showed a less intense response, and western blotting showed that eNOS expression was significantly lower in this group (p<0.05. Conclusions: Acute alcohol administration activated the cAMP pathway with positive effects on erectile function. In contrast, chronic alcohol administration changed the ultrastructures of the CC and suppressed eNOS expression, thereby leading to erectile dysfunction.

  20. CROATIAN ADULT SPOKEN LANGUAGE CORPUS (HrAL

    Directory of Open Access Journals (Sweden)

    Jelena Kuvač Kraljević

    2016-01-01

    Full Text Available Interest in spoken-language corpora has increased over the past two decades leading to the development of new corpora and the discovery of new facets of spoken language. These types of corpora represent the most comprehensive data source about the language of ordinary speakers. Such corpora are based on spontaneous, unscripted speech defined by a variety of styles, registers and dialects. The aim of this paper is to present the Croatian Adult Spoken Language Corpus (HrAL, its structure and its possible applications in different linguistic subfields. HrAL was built by sampling spontaneous conversations among 617 speakers from all Croatian counties, and it comprises more than 250,000 tokens and more than 100,000 types. Data were collected during three time slots: from 2010 to 2012, from 2014 to 2015 and during 2016. HrAL is today available within TalkBank, a large database of spoken-language corpora covering different languages (https://talkbank.org, in the Conversational Analyses corpora within the subsection titled Conversational Banks. Data were transcribed, coded and segmented using the transcription format Codes for Human Analysis of Transcripts (CHAT and the Computerised Language Analysis (CLAN suite of programmes within the TalkBank toolkit. Speech streams were segmented into communication units (C-units based on syntactic criteria. Most transcripts were linked to their source audios. The TalkBank is public free, i.e. all data stored in it can be shared by the wider community in accordance with the basic rules of the TalkBank. HrAL provides information about spoken grammar and lexicon, discourse skills, error production and productivity in general. It may be useful for sociolinguistic research and studies of synchronic language changes in Croatian.

  1. Proverb comprehension in individuals with agenesis of the corpus callosum.

    Science.gov (United States)

    Rehmel, Jamie L; Brown, Warren S; Paul, Lynn K

    2016-09-01

    Comprehension of non-literal language involves multiple neural systems likely involving callosal connections. We describe proverb comprehension impairments in individuals with isolated agenesis of the corpus callosum (AgCC) and normal-range general intelligence. Experiment 1 compared Gorham Proverb Test (Gorham, 1956) performance in 19 adults with AgCC and 33 neurotypical control participants of similar age, sex, and intelligence. Experiment 2 used the Proverbs subtest of the Delis-Kaplan Executive Function System (D-KEFS, 2001) to compare 19 adults with AgCC and 17 control participants with similar age, sex, and intelligence. Gorham Proverbs performance was impaired in the AgCC group for both the free-response and multiple-choice tasks. On the D-KEFS proverbs test, the AgCC group performed significantly worse on the free-response task (and all derivative scores) despite normal levels of performance on the multiple-choice task. Covarying verbal intelligence did not alter these outcomes. However, covarying a measure of non-literal language comprehension considerably reduced group differences in proverb comprehension on the Gorham test, but had little effect on the D-KEFS group differences. The difference between groups seemed to be greatest when participants had to generate their own interpretation (free response), or in the multiple choice format when the test included many proverbs that were likely to be less familiar. Taken together, the results of this study clearly show that proverb comprehension is diminished in individuals with AgCC compared to their peers. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. PET attenuation correction for rigid MR Tx/Rx coils from 176Lu background activity

    Science.gov (United States)

    Lerche, Christoph W.; Kaltsas, Theodoris; Caldeira, Liliana; Scheins, Jürgen; Rota Kops, Elena; Tellmann, Lutz; Pietrzyk, Uwe; Herzog, Hans; Shah, N. Jon

    2018-02-01

    One challenge for PET-MR hybrid imaging is the correction for attenuation of the 511 keV annihilation radiation by the required RF transmit and/or RF receive coils. Although there are strategies for building PET transparent Tx/Rx coils, such optimised coils still cause significant attenuation of the annihilation radiation leading to artefacts and biases in the reconstructed activity concentrations. We present a straightforward method to measure the attenuation of Tx/Rx coils in simultaneous MR-PET imaging based on the natural 176Lu background contained in the scintillator of the PET detector without the requirement of an external CT scanner or PET scanner with transmission source. The method was evaluated on a prototype 3T MR-BrainPET produced by Siemens Healthcare GmbH, both with phantom studies and with true emission images from patient/volunteer examinations. Furthermore, the count rate stability of the PET scanner and the x-ray properties of the Tx/Rx head coil were investigated. Even without energy extrapolation from the two dominant γ energies of 176Lu to 511 keV, the presented method for attenuation correction, based on the measurement of 176Lu background attenuation, shows slightly better performance than the coil attenuation correction currently used. The coil attenuation correction currently used is based on an external transmission scan with rotating 68Ge sources acquired on a Siemens ECAT HR  +  PET scanner. However, the main advantage of the presented approach is its straightforwardness and ready availability without the need for additional accessories.

  3. Isolated Norrie disease in a female caused by a balanced translocation t(X,6).

    Science.gov (United States)

    Meire, F M; Lafaut, B A; Speleman, F; Hanssens, M

    1998-12-01

    This is the second report of Norrie disease in a female patient with a de-novo balanced translocation t(X,6) with breakpoint at the location of the Norrie gene. At the age of 3 months, a girl was referred for suspected congenital glaucoma. The right eye was microphthalmic and ultrasonography was compatible with persistent hyperplasia of the primary vitreous. The left eye was also microphthalmic. The left cornea was larger than the right. The anterior chamber was virtual and leukocoria was evident. The eye felt hard digitally. Ultrasonography indicated an organized retinal detachment. The pathologic findings are reported and are compatible with Norrie disease.

  4. Decoupling of TX and RX antennas in a full-duplex mobile terminal

    DEFF Research Database (Denmark)

    Foroozanfard, Ehsan; Carvalho, Elisabeth De; Pedersen, Gert F.

    2016-01-01

    In this paper, a Full-duplex (FD) antenna system is presented with a high isolation between the TX and RX antennas. The isolation method is based on utilizing balanced antennas to localize the current on the ground plane and single mode excitation of the ground plane with capacitive coupling...... elements. The simulation results show a promising isolation level of 75 dB. User impact investigation on the antenna isolation, antenna matching and efficiency is presented. The isolation level varies from 60 dB to 30 dB in the worst user scenarios. The proposed antenna system can be used in a MISO/SIMO FD...

  5. Tank 241-TX-104, cores 230 and 231 analytical results for the final report

    International Nuclear Information System (INIS)

    Diaz, L.A.

    1998-01-01

    This document is the analytical laboratory report for tank 241-TX-104 push mode core segments collected between February 18, 1998 and February 23, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-104 Push Mode Core Sampling and Analysis Plan (TSAP) (McCain, 1997), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al., 1995) and the Safety Screening Data Quality Objective (DQO) (Dukelow, et.al., 1995). The analytical results are included in the data summary table. None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Alpha Activity (AT) exceeded notification limits as stated in the TSAP. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report. Appearance and Sample Handling Attachment 1 is a cross reference to relate the tank farm identification numbers to the 222-S Laboratory LabCore/LIMS sample numbers. The subsamples generated in the laboratory for analyses are identified in these diagrams with their sources shown. Core 230: Three push mode core segments were removed from tank 241-TX-104 riser 9A on February 18, 1998. Segments were received by the 222-S Laboratory on February 19, 1998. Two segments were expected for this core. However, due to poor sample recovery, an additional segment was taken and identified as 2A. Core 231: Four push mode core segments were removed from tank 241-TX-104 riser 13A between February 19, 1998 and February 23, 1998. Segments were received by the 222-S Laboratory on February 24, 1998. Two segments were expected for this core. However, due to poor sample recovery, additional segments were taken and identified as 2A and 2B. The TSAP states the core samples should be transported to the laboratory within three

  6. Klymollins T-X, bioactive eunicellin-based diterpenoids from the soft coral Klyxum molle.

    Science.gov (United States)

    Chang, Fang-Yu; Hsu, Fang-Jung; Tai, Chi-Jen; Wei, Wen-Chi; Yang, Ning-Sun; Sheu, Jyh-Horng

    2014-05-22

    Five new eunicellin-based diterpenoids, klymollins T-X (1-5), along with two known compounds (6 and 7) have been isolated from the soft coral Klyxum molle. The structures of these new metabolites were elucidated by extensive spectroscopic analysis and by comparison with related known compounds. Compound 5 was found to exert significant in vitro anti-inflammatory activity against LPS-stimulated RAW264.7 macrophage cells. Furthermore, compounds 4 and 7 were shown to exhibit cytotoxicity against a limited panel of human cancer cell lines.

  7. Rare processes with top quarks: FCNCs, tt+X, tttt, t+X

    CERN Document Server

    Li, Yichen; The ATLAS collaboration

    2018-01-01

    The latest ATLAS and CMS searches or measurements of rare processes with top quarks, including FCNCs, tt+X, tttt, and t+X, are presented. FCNC branching ratio limits are pushed to new low, with some of them even reaching the expected limits for some BSMs. Associated production of W/Z/photon with a pair of top quarks are established and their cross sections are measured. The evidence of associated production of Z boson with a top quark is found. While there is no evidence for the four top quark production yet.

  8. LyeTxI-b, a Synthetic Peptide Derived From Lycosa erythrognatha Spider Venom, Shows Potent Antibiotic Activity in Vitro and in Vivo

    Directory of Open Access Journals (Sweden)

    Pablo V. M. Reis

    2018-04-01

    Full Text Available The antimicrobial peptide LyeTxI isolated from the venom of the spider Lycosa erythrognatha is a potential model to develop new antibiotics against bacteria and fungi. In this work, we studied a peptide derived from LyeTxI, named LyeTxI-b, and characterized its structural profile and its in vitro and in vivo antimicrobial activities. Compared to LyeTxI, LyeTxI-b has an acetylated N-terminal and a deletion of a His residue, as structural modifications. The secondary structure of LyeTxI-b is a well-defined helical segment, from the second amino acid to the amidated C-terminal, with no clear partition between hydrophobic and hydrophilic faces. Moreover, LyeTxI-b shows a potent antimicrobial activity against Gram-positive and Gram-negative planktonic bacteria, being 10-fold more active than the native peptide against Escherichia coli. LyeTxI-b was also active in an in vivo model of septic arthritis, reducing the number of bacteria load, the migration of immune cells, the level of IL-1β cytokine and CXCL1 chemokine, as well as preventing cartilage damage. Our results show that LyeTxI-b is a potential therapeutic model for the development of new antibiotics against Gram-positive and Gram-negative bacteria.

  9. Vapor space characterization of waste Tank 241-TX-118 (in situ): Results from samples collected on 9/7/94

    International Nuclear Information System (INIS)

    Thomas, B.L.; Clauss, T.W.; Ligotke, M.W.; Pool, K.H.; McVeety, B.D.; Olsen, K.B.; Fruchter, J.S.; Goheen, S.C.

    1995-10-01

    This report describes inorganic and organic analyses results from in situ samples obtained from the headspace of the Hanford waste storage Tank 241-TX-118 (referred to as Tank TX-118). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH 3 ), nitrogen dioxide (NO 2 ), nitric oxide (NO), hydrogen cyanide (CHN), and water (H 2 O). Sampling for sulfur oxides (SO x ) was not requested. In addition, quantitative results were obtained for the 39 TO-14 compounds plus an additional 13 analytes. Hexane, normally included in the additional analytes, was removed because a calibration standard was not available during analysis of Tank TX-118 SUMMA trademark canisters. Of these, 12 were observed above the 5-ppbv reporting cutoff. Fourteen tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv and are reported with concentrations that are semiquantitative estimates based on internal-standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 86% of the total organic components in Tank TX-118. Permanent gas analysis was not conducted on the tank-headspace samples. Tank TX-118 is on both the Ferrocyanide and Organic Watch List

  10. Dictionary Writing System (DWS + Corpus Query Package (CQP: The Case of TshwaneLex

    Directory of Open Access Journals (Sweden)

    Gilles-Maurice de Schryver

    2011-10-01

    Full Text Available

    Abstract: In this article the integrated corpus query functionality of the dictionary compilation software TshwaneLex is analysed. Attention is given to the handling of both raw corpus data and annotated corpus data. With regard to the latter it is shown how, with a minimum of human effort, machine learning techniques can be employed to obtain part-of-speech tagged corpora that can be used for lexicographic purposes. All points are illustrated with data drawn from English and Northern Sotho. The tools and techniques themselves, however, are language-independent, and as such the encouraging outcomes of this study are far-reaching.

    Keywords: LEXICOGRAPHY, DICTIONARY, SOFTWARE, DICTIONARY WRITING SYS-TEM (DWS, CORPUS QUERY PACKAGE (CQP, TSHWANELEX, CORPUS, CORPUS ANNO-TATION, PART-OF-SPEECH TAGGER (POS-TAGGER, MACHINE LEARNING, NORTHERN SOTHO (SESOTHO SA LEBOA

    Samenvatting: Woordenboekaanmaaksysteem + corpusanalysepakket: een studie van TshwaneLex. In dit artikel wordt het geïntegreerde corpusanalysepakket van het woordenboekaanmaaksysteem TshwaneLex geanalyseerd. Aandacht gaat zowel naar het verwer-ken van onbewerkte corpusdata als naar geannoteerde corpusdata. Wat het laatste betreft wordt aangetoond hoe, met een minimum aan intellectuele arbeid, automatische leertechnieken met suc-ces kunnen worden ingezet om corpora voor lexicografische doeleinden aan te maken waarin de woordklassen expliciet worden vermeld. Alle stappen van de redenering worden geïllustreerd met gegevens uit het Engels en Noord-Sotho. De instrumenten en technieken zelf zijn echter allemaal taalonafhankelijk, waardoor de veelbelovende resultaten van deze studie verreikend zijn.

    Sleutelwoorden: LEXICOGRAFIE, WOORDENBOEK, SOFTWARE, WOORDENBOEK-AANMAAKSYSTEEM, CORPUSANALYSEPAKKET, TSHWANELEX, CORPUS, CORPUSANNO-TATIE, WOORDKLASSETAGGER, AUTOMATISCHE LEERTECHNIEKEN, NOORD-SOTHO

  11. Magnetic resonance findings of the corpus callosum in canine and feline lysosomal storage diseases.

    Directory of Open Access Journals (Sweden)

    Daisuke Hasegawa

    Full Text Available Several reports have described magnetic resonance (MR findings in canine and feline lysosomal storage diseases such as gangliosidoses and neuronal ceroid lipofuscinosis. Although most of those studies described the signal intensities of white matter in the cerebrum, findings of the corpus callosum were not described in detail. A retrospective study was conducted on MR findings of the corpus callosum as well as the rostral commissure and the fornix in 18 cases of canine and feline lysosomal storage diseases. This included 6 Shiba Inu dogs and 2 domestic shorthair cats with GM1 gangliosidosis; 2 domestic shorthair cats, 2 familial toy poodles, and a golden retriever with GM2 gangliosidosis; and 2 border collies and 3 chihuahuas with neuronal ceroid lipofuscinoses, to determine whether changes of the corpus callosum is an imaging indicator of those diseases. The corpus callosum and the rostral commissure were difficult to recognize in all cases of juvenile-onset gangliosidoses (GM1 gangliosidosis in Shiba Inu dogs and domestic shorthair cats and GM2 gangliosidosis in domestic shorthair cats and GM2 gangliosidosis in toy poodles with late juvenile-onset. In contrast, the corpus callosum and the rostral commissure were confirmed in cases of GM2 gangliosidosis in a golden retriever and canine neuronal ceroid lipofuscinoses with late juvenile- to early adult-onset, but were extremely thin. Abnormal findings of the corpus callosum on midline sagittal images may be a useful imaging indicator for suspecting lysosomal storage diseases, especially hypoplasia (underdevelopment of the corpus callosum in juvenile-onset gangliosidoses.

  12. A corpus for plant-chemical relationships in the biomedical domain.

    Science.gov (United States)

    Choi, Wonjun; Kim, Baeksoo; Cho, Hyejin; Lee, Doheon; Lee, Hyunju

    2016-09-20

    Plants are natural products that humans consume in various ways including food and medicine. They have a long empirical history of treating diseases with relatively few side effects. Based on these strengths, many studies have been performed to verify the effectiveness of plants in treating diseases. It is crucial to understand the chemicals contained in plants because these chemicals can regulate activities of proteins that are key factors in causing diseases. With the accumulation of a large volume of biomedical literature in various databases such as PubMed, it is possible to automatically extract relationships between plants and chemicals in a large-scale way if we apply a text mining approach. A cornerstone of achieving this task is a corpus of relationships between plants and chemicals. In this study, we first constructed a corpus for plant and chemical entities and for the relationships between them. The corpus contains 267 plant entities, 475 chemical entities, and 1,007 plant-chemical relationships (550 and 457 positive and negative relationships, respectively), which are drawn from 377 sentences in 245 PubMed abstracts. Inter-annotator agreement scores for the corpus among three annotators were measured. The simple percent agreement scores for entities and trigger words for the relationships were 99.6 and 94.8 %, respectively, and the overall kappa score for the classification of positive and negative relationships was 79.8 %. We also developed a rule-based model to automatically extract such plant-chemical relationships. When we evaluated the rule-based model using the corpus and randomly selected biomedical articles, overall F-scores of 68.0 and 61.8 % were achieved, respectively. We expect that the corpus for plant-chemical relationships will be a useful resource for enhancing plant research. The corpus is available at http://combio.gist.ac.kr/plantchemicalcorpus .

  13. Characterizing the Google Books Corpus: Strong Limits to Inferences of Socio-Cultural and Linguistic Evolution.

    Science.gov (United States)

    Pechenick, Eitan Adam; Danforth, Christopher M; Dodds, Peter Sheridan

    2015-01-01

    It is tempting to treat frequency trends from the Google Books data sets as indicators of the "true" popularity of various words and phrases. Doing so allows us to draw quantitatively strong conclusions about the evolution of cultural perception of a given topic, such as time or gender. However, the Google Books corpus suffers from a number of limitations which make it an obscure mask of cultural popularity. A primary issue is that the corpus is in effect a library, containing one of each book. A single, prolific author is thereby able to noticeably insert new phrases into the Google Books lexicon, whether the author is widely read or not. With this understood, the Google Books corpus remains an important data set to be considered more lexicon-like than text-like. Here, we show that a distinct problematic feature arises from the inclusion of scientific texts, which have become an increasingly substantive portion of the corpus throughout the 1900 s. The result is a surge of phrases typical to academic articles but less common in general, such as references to time in the form of citations. We use information theoretic methods to highlight these dynamics by examining and comparing major contributions via a divergence measure of English data sets between decades in the period 1800-2000. We find that only the English Fiction data set from the second version of the corpus is not heavily affected by professional texts. Overall, our findings call into question the vast majority of existing claims drawn from the Google Books corpus, and point to the need to fully characterize the dynamics of the corpus before using these data sets to draw broad conclusions about cultural and linguistic evolution.

  14. Magnetic Resonance Findings of the Corpus Callosum in Canine and Feline Lysosomal Storage Diseases

    Science.gov (United States)

    Hasegawa, Daisuke; Tamura, Shinji; Nakamoto, Yuya; Matsuki, Naoaki; Takahashi, Kimimasa; Fujita, Michio; Uchida, Kazuyuki; Yamato, Osamu

    2013-01-01

    Several reports have described magnetic resonance (MR) findings in canine and feline lysosomal storage diseases such as gangliosidoses and neuronal ceroid lipofuscinosis. Although most of those studies described the signal intensities of white matter in the cerebrum, findings of the corpus callosum were not described in detail. A retrospective study was conducted on MR findings of the corpus callosum as well as the rostral commissure and the fornix in 18 cases of canine and feline lysosomal storage diseases. This included 6 Shiba Inu dogs and 2 domestic shorthair cats with GM1 gangliosidosis; 2 domestic shorthair cats, 2 familial toy poodles, and a golden retriever with GM2 gangliosidosis; and 2 border collies and 3 chihuahuas with neuronal ceroid lipofuscinoses, to determine whether changes of the corpus callosum is an imaging indicator of those diseases. The corpus callosum and the rostral commissure were difficult to recognize in all cases of juvenile-onset gangliosidoses (GM1 gangliosidosis in Shiba Inu dogs and domestic shorthair cats and GM2 gangliosidosis in domestic shorthair cats) and GM2 gangliosidosis in toy poodles with late juvenile-onset. In contrast, the corpus callosum and the rostral commissure were confirmed in cases of GM2 gangliosidosis in a golden retriever and canine neuronal ceroid lipofuscinoses with late juvenile- to early adult-onset, but were extremely thin. Abnormal findings of the corpus callosum on midline sagittal images may be a useful imaging indicator for suspecting lysosomal storage diseases, especially hypoplasia (underdevelopment) of the corpus callosum in juvenile-onset gangliosidoses. PMID:24386203

  15. Lexicon and teaching: an analysis of the use of less frequent prepositions in a Spanish learners corpus

    Directory of Open Access Journals (Sweden)

    Jéssyca Camargo Cruz

    2017-08-01

    Full Text Available This article aims at presenting a quantitative research and the analysis of the use of prepositions that are less frequent (underused in a corpus of learners of Spanish as a foreign language. We have observed the use of contra, hacia, enfrente de, excepto and tras through Corpus Linguistics by contrasting this lexical set and a supplementary corpus, composed by normative and descriptive Spanish grammar and by an online reference corpus of Spanish (CREA. Therefore, we present analyses made on a corpus constituted by 276 writings (85.729 words, gathered from two groups of freshman Language/Letras students, from 2011 to 2013. The data were collected with the aid of the WordSmith Tools (version 6 software and its tools, WordList and Concord enabled us to extract the frequency list of the prepositions in the corpus of study, as well as to observe and analyse their respective uses based on the lines of concordance.

  16. Tank 241-TX-118, core 236 analytical results for the final report

    International Nuclear Information System (INIS)

    ESCH, R.A.

    1998-01-01

    This document is the analytical laboratory report for tank 241-TX-118 push mode core segments collected between April 1, 1998 and April 13, 1998. The segments were subsampled and analyzed in accordance with the Tank 241-TX-118 Push Mode Core sampling and Analysis Plan (TSAP) (Benar, 1997), the Safety Screening Data Quality Objective (DQO) (Dukelow, et al., 1995), the Data Quality Objective to Support Resolution of the Organic Complexant Safety Issue (Organic DQO) (Turner, et al, 1995) and the Historical Model Evaluation Data Requirements (Historical DQO) (Sipson, et al., 1995). The analytical results are included in the data summary table (Table 1). None of the samples submitted for Differential Scanning Calorimetry (DSC) and Total Organic Carbon (TOC) exceeded notification limits as stated in the TSAP (Benar, 1997). One sample exceeded the Total Alpha Activity (AT) analysis notification limit of 38.4microCi/g (based on a bulk density of 1.6), core 236 segment 1 lower half solids (S98T001524). Appropriate notifications were made. Plutonium 239/240 analysis was requested as a secondary analysis. The statistical results of the 95% confidence interval on the mean calculations are provided by the Tank Waste Remediation Systems Technical Basis Group in accordance with the Memorandum of Understanding (Schreiber, 1997) and are not considered in this report

  17. About the nanostructure of the ternary system water - [BMIm]PF6 - TX-100.

    Science.gov (United States)

    Bilgili, Harun; Bürger, Matthias; Stubenrauch, Cosima; Porada, Jan H

    2016-12-15

    Many efforts have been made to formulate water-IL microemulsions. One of the most intensely studied systems is H 2 O - 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIm]PF 6 ) - 4-octylphenol polyethoxylate (TX-100) and it is not questioned that this system forms microemulsions. The nanostructures observed for traditional microemulsions are postulated with the surfactant being adsorbed at the interface such that the hydrophilic EO sides intrude into the water domains, while the hydrophobic hydrocarbon chains are immersed into [BMIm]PF 6 . However, the high polarity of [BMIm]PF 6 and the observation that [BMIm]PF 6 mixes well with oligoethylene oxides but hardly with non-polar solvents like toluene or alkanes are not in line with this picture. We re-studied the ternary system H 2 O - [BMIm]PF 6 - TX-100 by measuring phase diagrams, determining tie-lines, and carrying out ROESY NMR and PFG NMR measurements. We found that the hydrophobic part of the surfactant interacts neither with water nor with [BMIm]PF 6 , while both solvents interact with the hydrophilic part of the surfactant. We suggest that the surfactant is not adsorbed at the interface between water and the IL, but forms normal spherical or elongated micelles or even continuous aggregates with the hydrocarbon chains forming the interior of the aggregates. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Tank characterization report for single-shell tank 241-TX-104

    International Nuclear Information System (INIS)

    FIELD, J.G.

    1999-01-01

    A major function of the Tank Waste Remediation System (TWRS) is to characterize waste in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis and other available information about a tank are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-TX-104. The objectives of this report are (1) to use characterization data in response to technical issues associated with tank 241-TX-104 waste, and (2) to provide a standard characterization of this waste in terms of a best-basis inventory estimate. Section 2.0 summarizes the response to technical issues, Section 3.0 shows the best-basis inventory estimate, Section 4.0 makes recommendations about the safety status of the tank and additional sampling needs. The appendices contain supporting data and information. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1997), Milestone M-44-15c, change request M-44-97-03 to ''issue characterization deliverables consistent with the Waste Information Requirements Document developed for FY 1999'' (Adams et al. 1998)

  19. Guidelines for Synthesis and Processing of 2D Titanium Carbide (Ti3C2Tx MXene)

    KAUST Repository

    Alhabeb, Mohamed

    2017-08-25

    Two-dimensional (2D) transition metal carbides, carbonitrides and nitrides (MXenes) were discovered in 2011. Since the original discovery, more than 20 different compositions have been synthesized by the selective etching of MAX phase and other precursors and many more theoretically predicted. They offer a variety of different properties, making the family promising candidates in a wide range of applications, such as energy storage, electromagnetic interference shielding, water purification, electrocatalysis and medicine. These solution-processable materials have the potential to be highly scalable, deposited by spin, spray or dip coating, painted or printed, or fabricated in a variety of ways. Due to this promise, the amount of research on MXenes has been increasing, and methods of synthesis and processing are expanding quickly. The fast evolution of the material can also be noticed in the wide range of synthesis and processing protocols that determine the yield of delamination, as well as the quality of the 2D flakes produced. Here we describe the experimental methods and best practices we use to synthesize the most studied MXene, titanium carbide (Ti3C2Tx), using different etchants and delamination methods. We also explain effects of synthesis parameters on the size and quality of Ti3C2Tx and suggest the optimal processes for the desired application.

  20. I will proclaim myself what I am : corpus stylistics and the language of Shakespeare’s soliloquies

    OpenAIRE

    Murphy, Sean Edward

    2015-01-01

    This article reports on a corpus stylistic study of the language of soliloquies in Shakespeare’s plays. Literary corpus stylistics can use corpus linguistic methods to test claims made by literary critics and identify hitherto unnoticed features. Existing literary studies of soliloquies tend to define and classify them, to trace the history of the form or to offer literary appreciation; yet they pay surprisingly little attention to the language which characterises soliloquies. By creating a s...

  1. Estrogen and oxytocin receptors in the canine corpus luteum during pregnancy and parturition

    Directory of Open Access Journals (Sweden)

    Gisele Almeida Lima Veiga

    2015-02-01

    Full Text Available The expression of genes encoding the receptors for estrogen (ERαmRNA and oxytocin (OTRmRNA was studied in the corpus luteum during pregnancy and parturition in dogs. Real-time PCR was performed to quantify the levels of ERαmRNA and OTRmRNA in the corpus luteum of bitches during Early (up to 20 days of gestation, Mid (20 to 40 days and Late Pregnancy (40 to 60 days, and Parturition (first stage of labor. The corpus luteum expressed mRNA for OTR, however ERα mRNA was not detected. There was a reduction of OTR mRNA expression in the corpus luteum from gestational Day 20 onward, which suggests an important role of OTR mRNA in the mechanism of pregnancy recognition in dogs. We concluded that the expression of OTR mRNA in canine corpus luteum vary over time, which support the idea that the sensitivity and response to hormone therapy can vary along the course of pregnancy and labor. Moreover, the canine CL lacks ERα mRNA expression during pregnancy.

  2. Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle

    Directory of Open Access Journals (Sweden)

    Xiang Li

    2012-01-01

    Full Text Available Aims of study. The aim of the present study was to investigate whether an ethanol extract of Scutellaria baicalensis (ESB relaxes penile corpus cavernosum muscle in organ bath experiments. Materials and methods. Changes in tension of cavernous smooth muscle strips were determined by penile strip chamber model and in penile perfusion model. Isolated endothelium-intact rabbit corpus cavernosum was precontracted with phenylephrine (PE and then treated with ESB. Results. ESB relaxed penile smooth muscle in a dose-dependent manner, and this was inhibited by pre-treatment with NG-nitro-l-arginine methyl ester (l-NAME, a nitric oxide (NO synthase inhibitor, and 1H-[1, 2, 4]-oxadiazolo-[4,3-α]-quinoxalin-1-one (ODQ, a soluble guanylyl cyclase (sGC inhibitor. ESB-induced relaxation was significantly attenuated by pretreatment with tetraethylammonium (TEA, a nonselective K+ channel blocker, and charybdotoxin, a selective Ca2+-dependent K+ channel inhibitor. ESB increased the cGMP levels of rabbit corpus cavernosum in a concentration-dependent manner without changes in cAMP levels. In a perfusion model of penile tissue, ESB also relaxed penile corpus cavernosum smooth muscle in a dose-dependent manner. Conclusion. Taken together, these results suggest that ESB relaxed rabbit cavernous smooth muscle via the NO/cGMP system and Ca2+-sensitive K+ channels in the corpus cavernosum.

  3. Morphometry of the corpus callosum in Chinese children: relationship with gender and academic performance

    International Nuclear Information System (INIS)

    Ng, Wing Hung Alex; Chan, Yu.Lung; Au, Kit Sum Agnes; Yeung, Ka Wai David; Kwan, Ting Fai; To, Cho Yee

    2005-01-01

    The corpus callosum has been widely studied, but no study has demonstrated whether its size and shape have any relationship with language and calculation performance. To examine the morphometry of the corpus callosum of normal Chinese children and its relationship with gender and academic performance. One hundred primary school children (63 boys, 37 girls; age 6.5-10 years) were randomly selected and the standardized academic performance for each was ascertained. On the mid-sagittal section of a brain MRI, the length, height and total area of the corpus callosum and its thickness at different sites were measured. These were correlated with sex and academic performance. Apart from the normal average dimension of the different parts of the corpus callosum, thickness at the body-splenium junction in the average-to-good performance group was significantly greater than the below-average performance group in Chinese language (P=0.005), English language (P=0.02) and mathematics (P=0.01). The remainder of the callosal thickness showed no significant relationship with academic performance. There was no significant sex difference in the thickness of any part of the corpus callosum. These findings raise the suggestion that language and mathematics proficiency may be related to the morphometry of the fibre connections in the posterior parietal lobes. (orig.)

  4. Jointly learning word embeddings using a corpus and a knowledge base

    Science.gov (United States)

    Bollegala, Danushka; Maehara, Takanori; Kawarabayashi, Ken-ichi

    2018-01-01

    Methods for representing the meaning of words in vector spaces purely using the information distributed in text corpora have proved to be very valuable in various text mining and natural language processing (NLP) tasks. However, these methods still disregard the valuable semantic relational structure between words in co-occurring contexts. These beneficial semantic relational structures are contained in manually-created knowledge bases (KBs) such as ontologies and semantic lexicons, where the meanings of words are represented by defining the various relationships that exist among those words. We combine the knowledge in both a corpus and a KB to learn better word embeddings. Specifically, we propose a joint word representation learning method that uses the knowledge in the KBs, and simultaneously predicts the co-occurrences of two words in a corpus context. In particular, we use the corpus to define our objective function subject to the relational constrains derived from the KB. We further utilise the corpus co-occurrence statistics to propose two novel approaches, Nearest Neighbour Expansion (NNE) and Hedged Nearest Neighbour Expansion (HNE), that dynamically expand the KB and therefore derive more constraints that guide the optimisation process. Our experimental results over a wide-range of benchmark tasks demonstrate that the proposed method statistically significantly improves the accuracy of the word embeddings learnt. It outperforms a corpus-only baseline and reports an improvement of a number of previously proposed methods that incorporate corpora and KBs in both semantic similarity prediction and word analogy detection tasks. PMID:29529052

  5. Morphometry of the corpus callosum in Chinese children: relationship with gender and academic performance

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Wing Hung Alex; Chan, Yu.Lung [Prince of Wales Hospital, Department of Diagnostic Radiology and Organ Imaging, Shatin, Hong Kong (Hong Kong); Au, Kit Sum Agnes [James Cook University, Department of Psychology, Townsville, Queensland (Australia); Yeung, Ka Wai David; Kwan, Ting Fai; To, Cho Yee

    2005-06-01

    The corpus callosum has been widely studied, but no study has demonstrated whether its size and shape have any relationship with language and calculation performance. To examine the morphometry of the corpus callosum of normal Chinese children and its relationship with gender and academic performance. One hundred primary school children (63 boys, 37 girls; age 6.5-10 years) were randomly selected and the standardized academic performance for each was ascertained. On the mid-sagittal section of a brain MRI, the length, height and total area of the corpus callosum and its thickness at different sites were measured. These were correlated with sex and academic performance. Apart from the normal average dimension of the different parts of the corpus callosum, thickness at the body-splenium junction in the average-to-good performance group was significantly greater than the below-average performance group in Chinese language (P=0.005), English language (P=0.02) and mathematics (P=0.01). The remainder of the callosal thickness showed no significant relationship with academic performance. There was no significant sex difference in the thickness of any part of the corpus callosum. These findings raise the suggestion that language and mathematics proficiency may be related to the morphometry of the fibre connections in the posterior parietal lobes. (orig.)

  6. Atrophy and magnetization transfer ratio of the corpus callosum in patients with Alzheimer's disease

    International Nuclear Information System (INIS)

    Imon, Yukari; Hanyu, Haruo; Iwamoto, Toshihiko; Takasaki, Masaru; Abe, Kimihiko

    1998-01-01

    We compared atrophy and magnetization transfer ratio (MTR) in the corpus callosum in patients with Alzheimer's disease and age-matched normal subjects. Fifteen patients with Alzheimer's disease and fourteen normal subjects received MRI. The corpus callosum was divided into three parts (anterior, middle, and posterior portions) on midsagittal slice, and their areas on T2-weighted reversed images and MTR on magnetization transfer contrast images in each portion were measured. The area and MTR decreased significantly in the posterior portion in patients with Alzheimer's disease. In the anterior portion, MTR decreased significantly, but although the area showed no significant change. In the middle portion, the area and MTR showed no significant change. MTR and the area was correlated in each portion in patients with Alzheimer's disease. The score of Hasegawa dementia scale-revised (HDS-R) and the area of the middle, posterior and total of corpus callosum were significantly related. The score of HDS-R and MTR in the anterior portion of corpus callosum were significantly related. The present study revealed decreases in MTR in the anterior portion of the corpus callosum of patients with Alzheimer's disease although the area showed no significant change, and this change suggests the increase in free water and/or the decrease in bound water in tissues, probably due to demyelination and axonal degeneration. (author)

  7. Penile erection responses of Nigella sativa seed extract on isolated rat corpus cavernosum

    Science.gov (United States)

    Aminyoto, M.; Ismail, S.

    2018-04-01

    Nigella sativa L. (NS) from Ranunculaceae family is known as black cumin in Indonesia. The seed has been used as an aphrodisiac in ethnobotanical studies and reported to have pharmacological activities such as antihypertensive through the relaxant effect of vascular smooth muscles but the direct effect to the blood vessels of the corpus cavernosum is still unknown. The purpose of this study was to examine the response of NS seed extract on penile erection in vitro. NS seeds were macerated in ethanol solvent for three days in room temperature and repeated for two times. Penile erection responses was assessed using isolated rat corpus cavernosum in Krebs-Henseleit solution, temperature 37°C, pH 7.4, aerated with carbogen gas. After acclimation, corpus cavernosum was contracted with a phenylephrine solution. Ethanolic extract of NS seeds or control solution were given after reaching the plateu phase of the highest contraction. This study showed that the contraction response of the corpus cavernosum decreased after addition of NS extract and this action was increased with the addition of the extract concentration. This study concluded that NS seed ethanol extract affects the penile erection response directly through the relaxation of blood vessels in the corpus cavernosum.

  8. Working Together: Contributions of Corpus Analyses and Experimental Psycholinguistics to Understanding Conversation.

    Science.gov (United States)

    Meyer, Antje S; Alday, Phillip M; Decuyper, Caitlin; Knudsen, Birgit

    2018-01-01

    As conversation is the most important way of using language, linguists and psychologists should combine forces to investigate how interlocutors deal with the cognitive demands arising during conversation. Linguistic analyses of corpora of conversation are needed to understand the structure of conversations, and experimental work is indispensable for understanding the underlying cognitive processes. We argue that joint consideration of corpus and experimental data is most informative when the utterances elicited in a lab experiment match those extracted from a corpus in relevant ways. This requirement to compare like with like seems obvious but is not trivial to achieve. To illustrate this approach, we report two experiments where responses to polar (yes/no) questions were elicited in the lab and the response latencies were compared to gaps between polar questions and answers in a corpus of conversational speech. We found, as expected, that responses were given faster when they were easy to plan and planning could be initiated earlier than when they were harder to plan and planning was initiated later. Overall, in all but one condition, the latencies were longer than one would expect based on the analyses of corpus data. We discuss the implication of this partial match between the data sets and more generally how corpus and experimental data can best be combined in studies of conversation.

  9. Analysis of high signal intensities of nontumorous conditions of corpus callosum on magnetic resonance T2-weighted images

    International Nuclear Information System (INIS)

    Kang, Moo Song; Kim, Chul Min; Chung, Chun Phil

    1995-01-01

    To evaluate high signal intensity of nontumorous conditions of corpus callosum on T2-weighted MR images. Forty nine patients with nontumorous high signal intensities involving corpus callosum on sagittal T2-weighted image were retrospectively analyzed. Nontumorous condition of corpus callosum were diffuse axonal injury (DAI, 19 cases), cerebral infarctions (16 cases), multiple sclerosis (MS, 5 cases), Wilson's disease (2 cases) and hydrocephalus (7 cases) that were diagnosed by clinical and MR findings. Numbers, configuration, involved thickness and sites of high signal intensities of corpus callosum were analyzed. DAI and infarctions showed either single or multiple lesions. MS and hydrocephalus showed multiple lesions, but Wilson's diseases showed single lesion. In DAI, infarctions and MS the lesions involved any part of corpus callosum, splenium in Wilson's disease, and all parts of corpus callosum in hydrocephalus. Wilson's disease showed only partial thickness involvement, and others involved partial or full thickness of corpus callosum. Configuration of high signal intensity was linear in most cases of hydrocephalus, and oval in Wilson's disease, and oval and confluent in MS, and variable in DAI and infarctions. High signal intensities of nontumorous conditions of corpus callosum revealed variable findings, and therefore, analysis of nontumorous high signal intensities of corpus callosum is not made by only MR findings but by conjuction with clinical aspects

  10. The importance of the corpus callosum in the diagnosis of multiple sclerosis

    International Nuclear Information System (INIS)

    Goossens-Merkt, H.; Mueller-Jensen, M.; Zanella, F.D.

    1991-01-01

    Besides MS there are a lot of diseases with lesions of the white matter, especially vascular diseases. In quest of a specific pattern in MRI of MS especially in early diagnosis the corpus callosum in patients with MS and in other diseases was analyzed. The progressive atrophy of the corpus callosum in the course of multiple sclerosis is well known. A good correlation between atrophy of the corpus callosum in T1 weighted MRI and the severity of organic mental disorder has been demonstrated. Since Atrophy however is an unspecific sign while demyelinating lesions are much more specific for MS, a brain region in which vascular lesions are rare but demyelinating lesions are more frequent, has been studied. (author). 10 refs.; 2 figs.; 1 tab

  11. A Corpus-based Study of English Vocabulary in Art Research Articles

    Directory of Open Access Journals (Sweden)

    Ping Wang

    2017-09-01

    Full Text Available The learning of English as a foreign language is an additional burden for art majors. This study aimed to examine high frequency words in art research articles to improve the efficiency of art majors’ English learning, especially their academic reading and writing. For this aim, the study built a corpus, analyzed data from art research articles and compared data with three base word lists. We found that the General Service List (GSL and the Academic Word List (AWL had a high coverage in our corpus, and there was a different high frequency word order in the Art Research Article Corpus (ARAC. These findings provide some implications for teaching English for art majors.

  12. Corpus linguistics and statistics with R introduction to quantitative methods in linguistics

    CERN Document Server

    Desagulier, Guillaume

    2017-01-01

    This textbook examines empirical linguistics from a theoretical linguist’s perspective. It provides both a theoretical discussion of what quantitative corpus linguistics entails and detailed, hands-on, step-by-step instructions to implement the techniques in the field. The statistical methodology and R-based coding from this book teach readers the basic and then more advanced skills to work with large data sets in their linguistics research and studies. Massive data sets are now more than ever the basis for work that ranges from usage-based linguistics to the far reaches of applied linguistics. This book presents much of the methodology in a corpus-based approach. However, the corpus-based methods in this book are also essential components of recent developments in sociolinguistics, historical linguistics, computational linguistics, and psycholinguistics. Material from the book will also be appealing to researchers in digital humanities and the many non-linguistic fields that use textual data analysis and t...

  13. Angular analysis of corpus callosum in 18 patients with frontonasal dysplasia

    Directory of Open Access Journals (Sweden)

    Giffoni Silvyo David Araújo

    2004-01-01

    Full Text Available Considering the rarity of the frontonasal dysplasia (FD and the few reports about it in a large casuistry using magnetic resonance image (MRI, we describe the results of the angular analysis of the corpus callosum of 18 individuals with FD (7 male, 11 female, using an easily-reproductive method. Group I had 12 individuals with isolated form and Group II had 6 individuals with FD syndromic with unknown etiology. The results are presented in set. Comparing with the control group, patients with FD presented alpha angle increase and beta and gamma angles reduction (p<0.05. Alpha and gamma angles express the relationship between the anterior portion of corpus callosum and the floor of 4th ventricle. Considering the embryonary development, these findings would occur secondarily to failure during the development of nasal capsula. Thus, angular anomaly in corpus callosum would be a usual finding, and not fortuitous in patients with FD.

  14. A critical re-examination of sexual dimorphism in the corpus callosum microstructure

    DEFF Research Database (Denmark)

    Westerhausen, René; Kompus, Kristiina; Dramsdahl, Margaretha

    2011-01-01

    the diffusion parameters did not correlate with regional callosal size. The present results indicate a stronger inter-hemispheric connectivity between the frontal lobes in males than females, which might be related to sex differences in hemispheric asymmetry and brain size........ The objective of the present DTI study was to re-examine microstructural sex differences in the corpus callosum, while controlling for corpus callosum size differences between sexes. We compared 41 female and 34 male participants using regional tract-based spatial statistics (TBSS) analysis. Clusters...... of significantly higher fractional anisotropy (FA) and lower diffusion strength in males compared to females were detected in the genu and truncus of the corpus callosum. However, only the sex difference located in the anterior genu subregions could be unequivocally interpreted. This was the only cluster where...

  15. ANR Corpus architecturae religiosae europeae [CARE]saec. IV-X

    Directory of Open Access Journals (Sweden)

    Christian Sapin

    2010-10-01

    Full Text Available Le projet ANR «Corpus des monuments religieux antérieurs à l’an Mil» [Corpus architecturae religiosae europeae/CARE – IV-X saec.] a débuté en janvier 2008. Il représente l’apport de la France à un programme international, initié en 2002 par l’IRCLAMA de Zagreb (Croatie . Ce corpus a pour objectif de recenser les édifices religieux d’Europe entre le IVe siècle et le tout début du XIe siècle. Il regroupe déjà l’Italie, l’Espagne, la Croatie, l’Europe centrale et demain, probablement, l’Irlande...

  16. Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist

    DEFF Research Database (Denmark)

    Strømgaard, Kristian; Mellor, Ian R; Andersen, Kim

    2002-01-01

    Philanthotoxin-12 (PhTX-12) is a novel potent and selective, noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). Homologues of PhTX-12 with 7-11 methylene groups between the primary amino group and the aromatic head-group were synthesized using solid-phase methodology. In vitro...

  17. PhTX-II a Basic Myotoxic Phospholipase A2 from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry

    Science.gov (United States)

    Huancahuire-Vega, Salomón; Ponce-Soto, Luis Alberto; Marangoni, Sergio

    2014-01-01

    A monomeric basic PLA2 (PhTX-II) of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-binding loop and the hydrophobic channel of access to the catalytic site, reflected in the high catalytic activity displayed by the enzyme. Moreover, PhTX-II PLA2 showed an allosteric behavior and its enzymatic activity was dependent on Ca2+. Examination of PhTX-II PLA2 by CD spectroscopy indicated a high content of alpha-helical structures, similar to the known structure of secreted phospholipase IIA group suggesting a similar folding. PhTX-II PLA2 causes neuromuscular blockade in avian neuromuscular preparations with a significant direct action on skeletal muscle function, as well as, induced local edema and myotoxicity, in mice. The treatment of PhTX-II by BPB resulted in complete loss of their catalytic activity that was accompanied by loss of their edematogenic effect. On the other hand, enzymatic activity of PhTX-II contributes to this neuromuscular blockade and local myotoxicity is dependent not only on enzymatic activity. These results show that PhTX-II is a myotoxic Asp49 PLA2 that contributes with toxic actions caused by P. hyoprora venom. PMID:25365526

  18. PhTX-II a Basic Myotoxic Phospholipase A2 from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Salomón Huancahuire-Vega

    2014-10-01

    Full Text Available A monomeric basic PLA2 (PhTX-II of 14149.08 Da molecular weight was purified to homogeneity from Porthidium hyoprora venom. Amino acid sequence by in tandem mass spectrometry revealed that PhTX-II belongs to Asp49 PLA2 enzyme class and displays conserved domains as the catalytic network, Ca2+-binding loop and the hydrophobic channel of access to the catalytic site, reflected in the high catalytic activity displayed by the enzyme. Moreover, PhTX-II PLA2 showed an allosteric behavior and its enzymatic activity was dependent on Ca2+. Examination of PhTX-II PLA2 by CD spectroscopy indicated a high content of alpha-helical structures, similar to the known structure of secreted phospholipase IIA group suggesting a similar folding. PhTX-II PLA2 causes neuromuscular blockade in avian neuromuscular preparations with a significant direct action on skeletal muscle function, as well as, induced local edema and myotoxicity, in mice. The treatment of PhTX-II by BPB resulted in complete loss of their catalytic activity that was accompanied by loss of their edematogenic effect. On the other hand, enzymatic activity of PhTX-II contributes to this neuromuscular blockade and local myotoxicity is dependent not only on enzymatic activity. These results show that PhTX-II is a myotoxic Asp49 PLA2 that contributes with toxic actions caused by P. hyoprora venom.

  19. Infarction of the entire corpus callosum as a complication in subarachnoid hemorrhage: A case report

    Directory of Open Access Journals (Sweden)

    Satoru Takahashi, M.D.

    2017-03-01

    Full Text Available The corpus callosum is the major commissural pathway connecting the cerebral hemispheres. This pathway receives its blood supply from anterior communicating artery, pericallosal artery, and posterior pericallosal artery. However, in some cases, the entire corpus callosum is supplied by median callosal artery; thus, occlusion of this artery can lead to infarction of the entire corpus callosum. Few reports have described this type of infarction, and no reports after subarachnoid hemorrhage (SAH exist. Here, we report on a 42-year-old female who was diagnosed with SAH after two aneurysms were discovered in bifurcation of left anterior cerebral artery (A1-A2. After successful clipping was performed, the patient was alert and had no neurological deficits; moreover, the computed tomography images that were acquired after the operation showed no evidence of infarction. Nine days after admittance to the hospital, drowsiness and weakness of the left limbs with brain swelling appeared and decompressive hemi-craniectomy was performed. Diagnostic cerebral angiography revealed vasospasms in both anterior and middle cerebral arteries, thus fasudil hydrochloride was administered intra-arterially. While blood flow in all arteries improved, diffusion-weighted magnetic resonance imaging detected infarction along the entire length of the corpus callosum and in the medial region of the right frontal lobe. We believe this infarction was due to secondary ischemia of median callosal artery. This case reminded us of the anatomical variation wherein median callosal artery is the sole blood supply line for the corpus callosum and demonstrated that infarction of the entire corpus callosum is possible.

  20. Afasia fluente. Materiales para su estudio.(Volumen 01 del Corpus PerLA)

    OpenAIRE

    Gallardo-Paúls, Beatriz; Sanmartín Sáez, Julia

    2005-01-01

    El corpus PerLA (“Percepción, Lenguaje y Afasia”), surge en el área de Lingüística General de la Universitat de València como respuesta a la necesidad de integrar el estudio de las patologías lingüísticas en las tendencias actuales de la pragmática y la lingüística de corpus. Para satisfacer las exigencias de estas disciplinas y disponer de datos con validez ecológica, se han realizado grabaciones a diferentes hablantes con afasia, en un contexto que intenta alejarse de las convenciones propi...

  1. Marchiafava-Bignami disease: magnetic resonance imaging findings in corpus callosum and subcortical white matter

    Energy Technology Data Exchange (ETDEWEB)

    Kawarabuki, Kentaro E-mail: bukky@h2.dion.ne.jp; Sakakibara, Takehiko; Hirai, Makoto; Yoshioka, Yuji; Yamamoto, Yasumasa; Yamaki, Tarumi

    2003-11-01

    A case of Marchiafava-Bignami disease (MBD) is presented using magnetic resonance imaging (MRI). A patient with a long history of alcoholism developed a gait disturbance with involuntary movements at the lower extremities. MRI scans taken at the onset showed no particular abnormalities. He progressed to a coma 10 days later. MRI scans taken 20 days after the onset showed a focal lesion at the genu of the corpus callosum and he was diagnosed as having MBD. In addition, multiple lesions were observed in bilateral frontoparietal subcortical white matter. These lesions demonstrated similar intense MRI signals as the corpus callosum.

  2. Using text mining techniques to extract phenotypic information from the PhenoCHF corpus.

    Science.gov (United States)

    Alnazzawi, Noha; Thompson, Paul; Batista-Navarro, Riza; Ananiadou, Sophia

    2015-01-01

    Phenotypic information locked away in unstructured narrative text presents significant barriers to information accessibility, both for clinical practitioners and for computerised applications used for clinical research purposes. Text mining (TM) techniques have previously been applied successfully to extract different types of information from text in the biomedical domain. They have the potential to be extended to allow the extraction of information relating to phenotypes from free text. To stimulate the development of TM systems that are able to extract phenotypic information from text, we have created a new corpus (PhenoCHF) that is annotated by domain experts with several types of phenotypic information relating to congestive heart failure. To ensure that systems developed using the corpus are robust to multiple text types, it integrates text from heterogeneous sources, i.e., electronic health records (EHRs) and scientific articles from the literature. We have developed several different phenotype extraction methods to demonstrate the utility of the corpus, and tested these methods on a further corpus, i.e., ShARe/CLEF 2013. Evaluation of our automated methods showed that PhenoCHF can facilitate the training of reliable phenotype extraction systems, which are robust to variations in text type. These results have been reinforced by evaluating our trained systems on the ShARe/CLEF corpus, which contains clinical records of various types. Like other studies within the biomedical domain, we found that solutions based on conditional random fields produced the best results, when coupled with a rich feature set. PhenoCHF is the first annotated corpus aimed at encoding detailed phenotypic information. The unique heterogeneous composition of the corpus has been shown to be advantageous in the training of systems that can accurately extract phenotypic information from a range of different text types. Although the scope of our annotation is currently limited to a single

  3. NCBI disease corpus: a resource for disease name recognition and concept normalization.

    Science.gov (United States)

    Doğan, Rezarta Islamaj; Leaman, Robert; Lu, Zhiyong

    2014-02-01

    Information encoded in natural language in biomedical literature publications is only useful if efficient and reliable ways of accessing and analyzing that information are available. Natural language processing and text mining tools are therefore essential for extracting valuable information, however, the development of powerful, highly effective tools to automatically detect central biomedical concepts such as diseases is conditional on the availability of annotated corpora. This paper presents the disease name and concept annotations of the NCBI disease corpus, a collection of 793 PubMed abstracts fully annotated at the mention and concept level to serve as a research resource for the biomedical natural language processing community. Each PubMed abstract was manually annotated by two annotators with disease mentions and their corresponding concepts in Medical Subject Headings (MeSH®) or Online Mendelian Inheritance in Man (OMIM®). Manual curation was performed using PubTator, which allowed the use of pre-annotations as a pre-step to manual annotations. Fourteen annotators were randomly paired and differing annotations were discussed for reaching a consensus in two annotation phases. In this setting, a high inter-annotator agreement was observed. Finally, all results were checked against annotations of the rest of the corpus to assure corpus-wide consistency. The public release of the NCBI disease corpus contains 6892 disease mentions, which are mapped to 790 unique disease concepts. Of these, 88% link to a MeSH identifier, while the rest contain an OMIM identifier. We were able to link 91% of the mentions to a single disease concept, while the rest are described as a combination of concepts. In order to help researchers use the corpus to design and test disease identification methods, we have prepared the corpus as training, testing and development sets. To demonstrate its utility, we conducted a benchmarking experiment where we compared three different

  4. Introducing the Geneva Multimodal expression corpus for experimental research on emotion perception.

    Science.gov (United States)

    Bänziger, Tanja; Mortillaro, Marcello; Scherer, Klaus R

    2012-10-01

    Research on the perception of emotional expressions in faces and voices is exploding in psychology, the neurosciences, and affective computing. This article provides an overview of some of the major emotion expression (EE) corpora currently available for empirical research and introduces a new, dynamic, multimodal corpus of emotion expressions, the Geneva Multimodal Emotion Portrayals Core Set (GEMEP-CS). The design features of the corpus are outlined and justified, and detailed validation data for the core set selection are presented and discussed. Finally, an associated database with microcoded facial, vocal, and body action elements, as well as observer ratings, is introduced.

  5. Comorbidity is an independent prognostic factor in women with uterine corpus cancer

    DEFF Research Database (Denmark)

    Noer, Mette C; Sperling, Cecilie; Christensen, Ib J

    2014-01-01

    OBJECTIVE: To determine whether comorbidity independently affects overall survival in women with uterine corpus cancer. DESIGN: Cohort study. SETTING: Denmark. STUDY POPULATION: A total of 4244 patients registered in the Danish Gynecologic Cancer database with uterine corpus cancer from 1 January....... RESULTS: Univariate survival analysis showed a significant (p independent prognostic factor with hazard ratios...... ranging from 1.27 to 1.42 in mild, 1.69 to 1.74 in moderate, and 1.72 to 2.48 in severe comorbidity. Performance status was independently associated to overall survival and was found to slightly reduce the prognostic impact of comorbidity. CONCLUSION: Comorbidity is an independent prognostic factor...

  6. Preliminary tank characterization report for single-shell tank 241-TX-103: Best-basis inventory

    International Nuclear Information System (INIS)

    Hendrickson, D.W.

    1997-01-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-103 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task. The best-basis inventory is based on an engineering assessment of waste type, process flowsheet data, early sample data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes (Kupfer et al. 1997) describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available

  7. Preliminary tank characterization report for single-shell tank 241-TX-101: best-basis inventory

    International Nuclear Information System (INIS)

    Kupfer, M.J.

    1997-01-01

    This document is a preliminary Tank Characterization Report (TCR). It only contains the current best-basis inventory (Appendix D) for single-shell tank 241-TX-101. No TCRs have been previously issued for this tank, and current core sample analyses are not available. The best-basis inventory, therefore, is based on an engineering assessment of waste type, process flowsheet data, early sample data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available

  8. Preliminary tank characterization report for single-shell tank 241-TX-111: Best-basis inventory

    International Nuclear Information System (INIS)

    Place, D.E.

    1997-01-01

    An effort is underway to provide waste inventory estimates that will serve as standard characterization source terms for the various waste management activities. As part of this effort, an evaluation of available information for single-shell tank 241-TX-111 was performed, and a best-basis inventory was established. This work follows the methodology that was established by the standard inventory task. The best-basis inventory is based on an engineering assessment of waste type, process flowsheet data, early sample data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes (Kupfer et al. 1997) describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available

  9. Preliminary tank characterization report for single-shell tank 241-TX-113: best-basis inventory

    International Nuclear Information System (INIS)

    Place, D.E.

    1997-01-01

    This document is a preliminary Tank Characterization Report (TCR). It only contains the current best-basis inventory (Appendix D) for single-shell tank 241-TX-113. No TCRs have been previously issued for this tank, and current core sample analyses are not available. The best-basis inventory, therefore, is based on an engineering assessment of waste type, process flowsheet data, early sample data, and/or other available information. The Standard Inventories of Chemicals and Radionuclides in Hanford Site Tank Wastes describes standard methodology used to derive the tank-by-tank best-basis inventories. This preliminary TCR will be updated using this same methodology when additional data on tank contents become available

  10. Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

    DEFF Research Database (Denmark)

    Andersen, Trine F; Vogensen, Stine B; Jensen, Lars S

    2005-01-01

    Polyamines and polyamine toxins are biologically important molecules, having modulatory effects on nucleotides and proteins. The wasp toxin, philanthotoxin-433 (PhTX-433), is a non-selective and uncompetitive antagonist of ionotropic receptors, such as ionotropic glutamate receptors and nicotinic...

  11. 78 FR 9907 - TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company, LLC v. Arizona...

    Science.gov (United States)

    2013-02-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-45-000] TGP Development Company, LLC; TGP Flying Cloud Holdings, LLC; WEC TX Company, LLC v. Arizona Public Service Company... section 206 of the Federal Power Act, 16 U.S.C. 824(e) (2006), TGP Development Company, LLC, TGP Flying...

  12. PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer

    Science.gov (United States)

    Garateix, Anoland; Salceda, Emilio; Zaharenko, André Junqueira; Pons, Tirso; Santos, Yúlica; Arreguín, Roberto; Ständker, Ludger; Forssmann, Wolf-Georg; Tytgat, Jan; Vega, Rosario

    2018-01-01

    Sea anemones produce proteinaceous toxins for predation and defense, including peptide toxins that act on a large variety of ion channels of pharmacological and biomedical interest. Phymanthus crucifer is commonly found in the Caribbean Sea; however, the chemical structure and biological activity of its toxins remain unknown, with the exception of PhcrTx1, an acid-sensing ion channel (ASIC) inhibitor. Therefore, in the present work, we focused on the isolation and characterization of new P. crucifer toxins by chromatographic fractionation, followed by a toxicity screening on crabs, an evaluation of ion channels, and sequence analysis. Five groups of toxic chromatographic fractions were found, and a new paralyzing toxin was purified and named PhcrTx2. The toxin inhibited glutamate-gated currents in snail neurons (maximum inhibition of 35%, IC50 4.7 µM), and displayed little or no influence on voltage-sensitive sodium/potassium channels in snail and rat dorsal root ganglion (DRG) neurons, nor on a variety of cloned voltage-gated ion channels. The toxin sequence was fully elucidated by Edman degradation. PhcrTx2 is a new β-defensin-fold peptide that shares a sequence similarity to type 3 potassium channels toxins. However, its low activity on the evaluated ion channels suggests that its molecular target remains unknown. PhcrTx2 is the first known paralyzing toxin in the family Phymanthidae. PMID:29414882

  13. PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer

    Directory of Open Access Journals (Sweden)

    Armando Alexei Rodríguez

    2018-02-01

    Full Text Available Sea anemones produce proteinaceous toxins for predation and defense, including peptide toxins that act on a large variety of ion channels of pharmacological and biomedical interest. Phymanthus crucifer is commonly found in the Caribbean Sea; however, the chemical structure and biological activity of its toxins remain unknown, with the exception of PhcrTx1, an acid-sensing ion channel (ASIC inhibitor. Therefore, in the present work, we focused on the isolation and characterization of new P. crucifer toxins by chromatographic fractionation, followed by a toxicity screening on crabs, an evaluation of ion channels, and sequence analysis. Five groups of toxic chromatographic fractions were found, and a new paralyzing toxin was purified and named PhcrTx2. The toxin inhibited glutamate-gated currents in snail neurons (maximum inhibition of 35%, IC50 4.7 µM, and displayed little or no influence on voltage-sensitive sodium/potassium channels in snail and rat dorsal root ganglion (DRG neurons, nor on a variety of cloned voltage-gated ion channels. The toxin sequence was fully elucidated by Edman degradation. PhcrTx2 is a new β-defensin-fold peptide that shares a sequence similarity to type 3 potassium channels toxins. However, its low activity on the evaluated ion channels suggests that its molecular target remains unknown. PhcrTx2 is the first known paralyzing toxin in the family Phymanthidae.

  14. 77 FR 70174 - Waterway Suitability Assessment for Expansion of Liquefied Gas Terminals; Houston and Texas City, TX

    Science.gov (United States)

    2012-11-23

    ... Assessment for Expansion of Liquefied Gas Terminals; Houston and Texas City, TX AGENCY: Coast Guard, DHS... Assessment to the Coast Guard Captain of the Port, Sector Houston-Galveston regarding the company's proposed expansion of its Liquefied Hazardous Gas (LHG) facilities in Houston and Texas City, Texas, and increased...

  15. 75 FR 8741 - Notice of Intent to Repatriate Cultural Items: Stephen F. Austin State University, Nacogdoches, TX

    Science.gov (United States)

    2010-02-25

    ...: Stephen F. Austin State University, Nacogdoches, TX AGENCY: National Park Service, Interior. ACTION... Act (NAGPRA), 25 U.S.C. 3005, of the intent to repatriate cultural items in the control of Stephen F... of Oklahoma, which was under contract with Stephen F. Austin State University. In 1957, 15 cultural...

  16. GIS applications in eco-logical grant projects : peer exchange summary report Austin, TX July 22-23, 2009

    Science.gov (United States)

    2009-10-31

    This report provides a summary of a 1.5-day peer exchange convened with select recipients of FHWA's first Eco-Logical grant. The purpose of the exchange, which was held in Austin, TX, in July 2009, was to allow grant recipients the opportunity to sha...

  17. 78 FR 42036 - Radio Broadcasting Services; Port Lions, AK, De Beque, CO, Benjamin, Cisco, Rule, and Shamrock, TX

    Science.gov (United States)

    2013-07-15

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 13-156; DA 13-1377] Radio Broadcasting Services; Port Lions, AK, De Beque, CO, Benjamin, Cisco, Rule, and Shamrock, TX AGENCY: Federal..., under Texas, Channel 237C3; Cisco, Channel 261C3; Rule, Channel 288C2; and Shamrock, Channel 225C2. [FR...

  18. FREEDOM OF COMBINATION AND HETEROGENEITY: A CORPUS LINGUIST’S LOOK AT TWO SAUSSUREAN INSIGHTS

    Directory of Open Access Journals (Sweden)

    Tony Berber Sardinha

    2014-06-01

    Full Text Available This article offers a reexamination of two of Saussure’s insights from the point of view of corpus linguistics—namely, freedom of combination and heterogeneity in language in use. Regarding the first insight, an analysis of word combinations in a corpus of newspaper texts written in Brazilian Portuguese was carried out to determine how many of these combinations were actual collocations—that is, were used frequently enough in a very large reference corpus (the Brazilian corpus to warrant statistical significance. The results suggested that most word combinations are not free; rather, they follow previously established preferences among speakers. Regarding the second notion, that of heterogeneity, the collocations in the newspaper texts were tracked as they were deployed one after the other along each text, and this flow was visually depicted. The inspection of the charts revealed unique patterns of the distribution of collocation, thereby suggesting that the evidence supports the view of heterogeneity. A cluster analysis was later conducted on the amount of collocations in each text, revealing three basic collocation bands onto which all the texts can be fitted. This was interpreted as suggesting that heterogeneity, despite being present and noticeable, is constrained rather than limitless. The article concludes that the methods and techniques afforded by present-day corpus linguistics can shed light onto Saussure’s many valuable insights. ------------------------------------------------------------------------------ LIBERDADE DE COMBINAÇÃO E HETEROGENEIDADE: UM OLHAR DA LINGUÍSTICA DE CORPUS EM DOIS INSIGHTS SAUSSUREANOS O artigo reexamina dois dos insights de Saussure a partir da perspectiva da linguística de corpus, a saber a liberdade de combinação e a heterogeneidade no uso da língua. Com relação ao primeiro, foi feita uma análise de combinações de palavras em corpus de textos de jornais para determinar quantas eram

  19. Macroscopic morphometry of the corpus luteum of pregnant and non-pregnant zebu cows in the Colombian tropics

    Directory of Open Access Journals (Sweden)

    Marco González T

    2017-07-01

    Full Text Available The objective of the study was to determine the volume, weight, measures, ovarian location and shape of the corpus luteum of pregnant and non - pregnant cows from zebu cows of the Colombian tropics. 528 reproductive tracts were collected; 264 pregnant and 264 non-pregnant of cows benefited at the local slaughterhouse in Monteria, Córdoba, Colombia. The period of collection of the samples was extended for three months. After collection of each reproductive tract, the ovaries were separated, identified as right and left, weighed and measured. Then the drawing of the location of the corpus luteum was performed on the ovary according to the anatomical planes previously established in the corresponding form. Subsequently the corpus luteum was removed to perform their measurements, weighings and visualization of their shape. There were statistical differences between the locations of the corpus luteum in the ovary: Anterior pole, posterior pole, free edge, upper face and lower face (p≤0.05. The weight and volume of gestational corpus luteum was greater by 30 and 27.9% than the corpus luteum of non-pregnant cows. The predominant form por shape of the corpus luteum in both pregnant and non-pregnant cows was oval, then pyramidal and finally rounded. No gestation was observed contralateral to the location of the corpus luteum.

  20. Assessing the Lexico-Grammatical Characteristics of a Corpus of College-Level Statistics Textbooks: Implications for Instruction and Practice

    Science.gov (United States)

    Wagler, Amy E.; Lesser, Lawrence M.; González, Ariel I.; Leal, Luis

    2015-01-01

    A corpus of current editions of statistics textbooks was assessed to compare aspects and levels of readability for the topics of "measures of center," "line of fit," "regression analysis," and "regression inference." Analysis with lexical software of these text selections revealed that the large corpus can…

  1. Variation in Citational Practice in a Corpus of Student Biology Papers: From Parenthetical Plonking to Intertextual Storytelling

    Science.gov (United States)

    Swales, John M.

    2014-01-01

    This is a corpus-based study of a key aspect of academic writing in one discipline (biology) by final-year undergraduates and first-, second-, and third-year graduate students. The papers come from the Michigan Corpus of Upper-level Student Papers, a freely available electronic database. The principal aim of the study is to examine the extent of…

  2. Automatic recognition of touch gestures in the corpus of social touch

    NARCIS (Netherlands)

    Jung, Merel Madeleine; Poel, Mannes; Poppe, Ronald Walter; Heylen, Dirk K.J.

    For an artifact such as a robot or a virtual agent to respond appropriately to human social touch behavior, it should be able to automatically detect and recognize touch. This paper describes the data collection of CoST: Corpus of Social Touch, a data set containing 7805 captures of 14 different

  3. Applications of the Buckeye GTA Corpus for L2 teaching and research

    DEFF Research Database (Denmark)

    Hardman, Jocelyn; McCullough, Elizabeth

    The Buckeye GTA Corpus contains 9,664 L1 and L2 sentence productions by 89 talkers (27 American English, 19 Hindi, 23 Mandarin, & 20 Korean). A total of 5,696 sentences were read in English, with each talker contributing 64 sentences. Hindi, Mandarin, and Korean talkers also read 64 sentences each...

  4. Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality

    International Nuclear Information System (INIS)

    Griffiths, Paul D.; Batty, Ruth; Connolly, Dan J.A.; Reeves, Michael J.

    2009-01-01

    The midline structures of the supra-tentorial brain are important landmarks for judging if the brain has formed correctly. In this article, we consider the normal appearances of the corpus callosum, septum pellucidum and fornix as shown on MR imaging in normal and near-normal states. (orig.)

  5. White matter changes contribute to corpus callosum atrophy in the elderly: The LADIS study

    DEFF Research Database (Denmark)

    Ryberg, C.; Rostrup, E.; Sjöstrand, Karl

    2008-01-01

    BACKGROUND AND PURPOSE: The corpus callosum (CC) is the most important structure involved in the transmission of interhemispheric information. The aim of this study was to investigate the potential correlation between regional age-related white matter changes (ARWMC) and atrophy of CC in elderly ...

  6. Measuring the readability of sustainability reports: : A corpus-based analysis through standard formulae and NLP

    NARCIS (Netherlands)

    Smeuninx, N.; De Clerck, B.; Aerts, Walter

    2016-01-01

    This study characterises and problematises the language of corporate reporting along region, industry, genre, and content lines by applying readability formulae and more advanced natural language processing (NLP)–based analysis to a manually assembled 2.75-million-word corpus. Readability formulae

  7. Lexical Analysis of the Verb "COOK" and Learning Vocabulary: A Corpus Study

    Science.gov (United States)

    Priyono

    2011-01-01

    English verbs have built-in properties that determine how they behave syntactically and generate appropriate meaning associated. With these inherent properties some verbs can fill in only in certain syntactic structures and some in others. The observation of the verb "COOK" using English corpus has revealed its lexical properties…

  8. JaSlo: Integration of a Japanese-Slovene Bilingual Dictionary with a Corpus Search System

    Directory of Open Access Journals (Sweden)

    Kristina HMELJAK SANGAWA

    2012-12-01

    Full Text Available The paper presents a set of integrated on-line language resources targeted at Japanese language learners, primarily those whose mother tongue is Slovene. The resources consist of the on-line Japanese-Slovene learners’ dictionary jaSlo and two corpora, a 1 million word Japanese-Slovene parallel corpus and a 300 million word corpus of web pages, where each word and sentence is marked by its difficulty level; this corpus is furthermore available as a set of five distinct corpora, each one containing sentences of the particular level. The corpora are available for exploration through NoSketch Engine, the open source version of the commercial state-of-the-art corpus analysis software Sketch Engine. The dictionary is available for Web searching, and dictionary entries have direct links to examples from the corpora, thus offering a wider picture of a possible translations in concrete contextualised examples, and b monolingual Japanese usage examples of different difficulty levels to support language learning.

  9. Therapy-related change of corpus callosum in a young patient with epilepsy

    International Nuclear Information System (INIS)

    Feitova, V.; Krupa, P.; Feit, J.

    2002-01-01

    Focal nonhemorrhagic lesion in the splenium of the corpus callosum in a patient with epilepsy treated with antiepileptic drugs was observed with MRI imaging. We have found only one such case during the past 2 years (series of MRI examinations of approximately 500 patients with various forms of epilepsy). (orig.)

  10. A Lingüística de corpus: história, problemas, legitimidade

    Directory of Open Access Journals (Sweden)

    Jacqueline Léon

    2006-01-01

    Full Text Available During the nineties, the accessibility of large corpora and the possibility of manipulation of enormous quantities of linguistic data was the origin of a renewal of interest in statistical and probability evidences that served to directly question linguistics about its objectives, methods and foundations. This interest gained increasing importance and became important currently under the name of corpus linguistics, a field of dominant research in language science. In this article we will show that the designation corpus linguistics covers considerably heterogeneous theoretical positions and research, topics. We show how corpus linguistics, originally of british origin, was later endowed with historical and theoretical legitimacy while at the same time intending to establish itself as a new paradigm in language science. Finally we distinguish two attitudes inside the british tradition: one, intending to build the studies on a corpus and in a new paradigm based on a retrospective construction of the critical works of chomsky during the years 1959 and 1960, which was intended to legitimize the studies; the other attitude involves the continuity of the tradition of british empirical linguistics.

  11. How Can We Use Corpus Wordlists for Language Learning? Interfaces between Computer Corpora and Expert Intervention

    Science.gov (United States)

    Chen, Yu-Hua; Bruncak, Radovan

    2015-01-01

    With the advances in technology, wordlists retrieved from computer corpora have become increasingly popular in recent years. The lexical items in those wordlists are usually selected, according to a set of robust frequency and dispersion criteria, from large corpora of authentic and naturally occurring language. Corpus wordlists are of great value…

  12. Effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits.

    Science.gov (United States)

    Yildirim, M K; Bagcivan, I; Sarac, B; Kilicarslan, H; Yildirim, S; Kaya, T

    2008-01-01

    Several studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. Hypothyroidism has been reported to occur in 6% of impotent men. In the present study, we examined purinergic relaxation responses in hypothyroidism in an experimental rabbit model and compared them with controls to evaluate the possible involvement of the purinergic pathway. The study comprised 20 male New Zealand white rabbits. The rabbits were divided into two equal groups. We tested the effects of ATP, alpha beta ATP, and adenosine precontracted with phenylephrine on the isolated corpus cavernosum preparations from control and hypothyroid rabbits. We also evaluated the effects of ATP, alpha beta ATP, and adenosine on the cGMP levels in the isolated corpus cavernosum preparations from control and hypothyroid rabbits. T3, T4, and testosterone levels were significantly lower in hypothyroid rabbits. ATP, alpha beta ATP, carbachol, and electrical field stimulation (EFS)-induced frequency-dependent relaxation responses in the isolated rabbit corpus cavernosum strips precontracted with phenylephrine reduced significantly (Phypothyroid rabbits. Reduction of relaxation response in hypothyroid rabbits corpus cavernosum can depend on a decreased release of nitric oxide (NO) from nitrergic nerves and endothelium.

  13. Touching the Void - Introducing CoST: Corpus of Social Touch

    NARCIS (Netherlands)

    Jung, Merel M.; Poppe, Ronald; Poel, Mannes; Heylen, Dirk K. J.

    2014-01-01

    Touch behavior is of great importance during social interaction. To transfer the tactile modality from interpersonal interaction to other areas such as Human-Robot Interaction (HRI) and remote communication automatic recognition of social touch is necessary. This paper introduces CoST: Corpus of

  14. Analyzing Idioms and Their Frequency in Three Advanced ILI Textbooks: A Corpus-Based Study

    Science.gov (United States)

    Alavi, Sepideh; Rajabpoor, Aboozar

    2015-01-01

    The present study aimed at identifying and quantifying the idioms used in three ILI "Advanced" level textbooks based on three different English corpora; MICASE, BNC and the Brown Corpus, and comparing the frequencies of the idioms across the three corpora. The first step of the study involved searching the books to find multi-word…

  15. Development and Use of a Corpus Tailored for Legal English Learning

    Science.gov (United States)

    Skier, Jason; Vibulphol, Jutarat

    2016-01-01

    While corpus linguistics has been applied towards many specific academic purposes, reports are few regarding its use to facilitate learning of legal English by non-native English speakers. Specialized corpora are required because legal English often differs significantly from ordinary usage, with words such as bar, motion, and hearing having…

  16. Multimodal Corpus Analysis as a Method for Ensuring Cultural Usability of Embodied Conversational Agents

    DEFF Research Database (Denmark)

    Nakano, Yukiko; Rehm, Matthias

    2009-01-01

    In this paper we propose the method of multimodal corpus analysis to collect enough empirical data for modeling the behavior of embodied conversational agents. This is a prerequisite to ensure the usability of such complex interactive systems. So far, the development of embodied agents suffers fr...

  17. Advantages and Disadvantages in the Use of Internet as a Corpus

    DEFF Research Database (Denmark)

    Tarp, Sven; Fuertes-Olivera, Pedro A.

    2016-01-01

    This paper initially discusses some of the consequences which the technological development has for lexicography, especially in terms of the different types of empirical basis which can be used in dictionary projects. The most important advantages and disadvantages of using the Internet as a corpus...

  18. Using a Corpus-Informed Pedagogical Intervention to Develop Language Awareness toward Appropriate Lexicogrammatical Choices

    Science.gov (United States)

    Fernandez, Julieta; Yuldashev, Aziz

    2015-01-01

    The corpus-informed pedagogical intervention described in this article was developed for an advanced English as a Second Language (ESL) course designed for prospective International Teaching Assistants (ITAs) and implemented over the course of two class periods. Its primary goal was to offer students opportunities to gain language awareness of…

  19. Aicardi's syndrome: (agenesis of the corpus callosum, infantile spasms, and ocular anomalies).

    Science.gov (United States)

    Dinani, S; Jancar, J

    1984-06-01

    A case of Aicardi's syndrome is reported. A 12-year-old mentally handicapped female has all the characteristics of the syndrome: agenesis of the Corpus callosum; female infant with mental handicap, epilepsy, characteristic eye lesions, vertebral anomalies and abnormal EEG pattern. The results of supporting examination and investigations are noted.

  20. Towards a corpus of South African English: corralling the sub-varieties

    African Journals Online (AJOL)

    Riette Ruthven

    important step towards the creation of a truly representative large corpus of SAE and ... Census data which elicit information about home language do not tell .... ISAE has absorbed lexical items such as robot (traffic light), dagha (mud), baba- ..... used their access to existing social networks to identify other contributors to.

  1. Linguistic Markers of Stance in Early and Advanced Academic Writing: A Corpus-Based Comparison

    Science.gov (United States)

    Aull, Laura L.; Lancaster, Zak

    2014-01-01

    This article uses corpus methods to examine linguistic expressions of stance in over 4,000 argumentative essays written by incoming first-year university students in comparison with the writing of upper-level undergraduate students and published academics. The findings reveal linguistic stance markers shared across the first-year essays despite…

  2. Extracting (good) discourse examples from an oral specialised corpus of wine tasting interactions

    DEFF Research Database (Denmark)

    Leroyer, Patrick; Gautier, Laurent; Maazaoui, Hedi

    This article explains how lexicographic examples have been extracted from a corpus of professional interactions on wine tasting for the purpose of including them i the Oenolex wine dictionary. Particularly, it explains how the SONAL software was used to analyse and process audio data and export...

  3. Integrity of the corpus callosum in patients with periventricular nodular heterotopia related epilepsy by FLNA mutation

    Directory of Open Access Journals (Sweden)

    Wenyu Liu

    2018-01-01

    Conclusions: These findings support the conclusion that patients with epilepsy secondary to PNH present widespread microstructural changes found in the corpus callosum that extend beyond the macroscopic MRI-visible lesions. This study also indicates that FLNA may affect white matter integrity in this disorder.

  4. MRI Findings of Coexistence of Ectopic Neurohypophysis, Corpus Callosum Dysgenesis, and Periventricular Neuronal Heterotopia

    Directory of Open Access Journals (Sweden)

    Harun Arslan

    2014-01-01

    Full Text Available Ectopic neurohypophysis is a pituitary gland abnormality, which can accompany growth hormone deficiency associated with dwarfism. Here we present magnetic resonance imaging (MRI findings of a rare case of ectopic neurohypophysis, corpus callosum dysgenesis, and periventricular neuronal heterotopia coexisting, with a review of the literature.

  5. Advantages and disadvantages in the use of internet as a corpus ...

    African Journals Online (AJOL)

    This paper initially discusses some of the consequences which the technological development has for lexicography, especially in terms of the different types of empirical basis which can be used in dictionary projects. The most important advantages and disadvantages of using the Internet as a corpus are then listed and ...

  6. A Pedagogic Corpus Analysis: Modal Auxiliary Verbs in Malaysian English Textbooks

    Science.gov (United States)

    Khojasteh, Laleh; Mukundan, Jayakaran

    2011-01-01

    Using corpus approach, over the past two decades, a growing number of researchers started to blame textbooks for neglecting important information on the use of grammatical structures in real language use and provided ample information about the mismatch between language used in textbooks and real language in use. Likewise, the prescribed Malaysian…

  7. Le corpus lexicographique dans les langues à tradition orale: le cas ...

    African Journals Online (AJOL)

    rbr

    langues à tradition orale: les informateurs et la représentativité du corpus. Cette dernière, qui doit ..... les techniques, les instruments, la pêche par les hommes, la pêche par .... cet outil indispensable qu'est le dictionnaire. Je pense que ces ...

  8. Tag Questions across Irish English and British English: A Corpus Analysis of Form and Function

    Science.gov (United States)

    Barron, Anne; Pandarova, Irina; Muderack, Karoline

    2015-01-01

    The present study, situated in the area of variational pragmatics, contrasts tag question (TQ) use in Ireland and Great Britain using spoken data from the Irish and British components of the International Corpus of English (ICE). Analysis is on the formal and functional level and also investigates form-functional relationships. Findings reveal…

  9. Involvement of corpus callosum in amyotrophic lateral sclerosis shown by MRI

    Energy Technology Data Exchange (ETDEWEB)

    Zandijcke, M. van [Dept. of Neurology, Bruges (Belgium); Casselman, J. [Dept. of Medical Imaging, Bruges (Belgium)

    1995-05-01

    Abnormal high signal in the corticospinal tracts on MRI has been described in amyotrophic lateral sclerosis. We report a case with further high signal in fibres of the corpus callosum on proton density and T2-weighted spin-echo images, closely matching findings of earlier pathological reports. (orig.)

  10. Involvement of corpus callosum in amyotrophic lateral sclerosis shown by MRI

    International Nuclear Information System (INIS)

    Zandijcke, M. van; Casselman, J.

    1995-01-01

    Abnormal high signal in the corticospinal tracts on MRI has been described in amyotrophic lateral sclerosis. We report a case with further high signal in fibres of the corpus callosum on proton density and T2-weighted spin-echo images, closely matching findings of earlier pathological reports. (orig.)

  11. Cluster Analysis of the Newcastle Electronic Corpus of Tyneside English: A Comparison of Methods

    NARCIS (Netherlands)

    Moisl, Hermann; Jones, Valerie M.

    2005-01-01

    This article examines the feasibility of an empirical approach to sociolinguistic analysis of the Newcastle Electronic Corpus of Tyneside English using exploratory multivariate methods. It addresses a known problem with one class of such methods, hierarchical cluster analysis—that different

  12. Cluster Analysis of the Newcastle Electronic Corpus of Tyneside English: In A Comparison of Methods

    NARCIS (Netherlands)

    Moisl, Hermann; Jones, Valerie M.

    2005-01-01

    This article examines the feasibility of an empirical approach to sociolinguistic analysis of the Newcastle Electronic Corpus of Tyneside English using exploratory multivariate methods. It addresses a known problem with one class of such methods, hierarchical cluster analysis—that different

  13. Task Dependency Effects of Collaboration in Learners' Corpus Consultation: An Exploratory Case Study

    Science.gov (United States)

    Cho, Hyeyoung

    2016-01-01

    Collaborative learning has attracted attention as pedagogic mediation to assist learners' corpus consultation, but some studies have pointed to negative aspects of collaboration. Based on the two sides of collaboration in language learning, this study presents a qualitative investigation of different effects of collaboration depending on task…

  14. A unified approach for development of Urdu Corpus for OCR and demographic purpose

    Science.gov (United States)

    Choudhary, Prakash; Nain, Neeta; Ahmed, Mushtaq

    2015-02-01

    This paper presents a methodology for the development of an Urdu handwritten text image Corpus and application of Corpus linguistics in the field of OCR and information retrieval from handwritten document. Compared to other language scripts, Urdu script is little bit complicated for data entry. To enter a single character it requires a combination of multiple keys entry. Here, a mixed approach is proposed and demonstrated for building Urdu Corpus for OCR and Demographic data collection. Demographic part of database could be used to train a system to fetch the data automatically, which will be helpful to simplify existing manual data-processing task involved in the field of data collection such as input forms like Passport, Ration Card, Voting Card, AADHAR, Driving licence, Indian Railway Reservation, Census data etc. This would increase the participation of Urdu language community in understanding and taking benefit of the Government schemes. To make availability and applicability of database in a vast area of corpus linguistics, we propose a methodology for data collection, mark-up, digital transcription, and XML metadata information for benchmarking.

  15. Age-related signal intensity changes in the corpus callosum: assessment with three orthogonal FLAIR images

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Akira; Miki, Yukio; Kanagaki, Mitsunori; Takahashi, Takahiro; Fushimi, Yasutaka; Haque, Tabassum Laz; Togashi, Kaori [Kyoto University, Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto (Japan); Tomimoto, Hidekazu [Kyoto University, Department of Neurology, Graduate School of Medicine, Kyoto (Japan); Konishi, Junya [Kobe University, Department of Radiology, Graduate School of Medicine, Kobe, Hyogo (Japan)

    2005-11-01

    The presence of age-related hyperintensities of the corpus callosum has not been thoroughly evaluated. Fifty-two patients of 50 years of age or older (mean, 71 years; range, 50-87 years) were included in this study. Fluid-attenuated inversion recovery images were obtained in three orthogonal planes. Periventricular hyperintensities (PVHs) and deep white matter hyperintensities (DWMHs) were graded according to Fazekas' rating scale. Correlations between the presence of hyperintensities in the corpus callosum and age, and the grade of PVH and DWMH were statistically analyzed. PVH was categorized as grade 0 (n=4), grade 1 (n=28), grade 2 (n=10), or grade 3 (n=10). DWMH was categorized as grade 0 (n=4), grade 1 (n=25), grade 2 (n=8), or grade 3 (n=15). Hyperintensity was considered present in the corpus callosum in 31 of the 52 patients (60%). In these 31 patients, PVH was categorized as grade 1 (n=16), grade 2 (n=7), or grade 3 (n=8), while DWMH was categorized as grade 0 (n=1), grade 1 (n=10), grade 2 (n=7), or grade 3 (n=13). The presence of callosal hyperintensities was significantly correlated with age (p=0.001), and with PVH (p=0.04) and DWMH grades (p=0.004). Hyperintensities may be present in the corpus callosum with aging, and are correlated with PVH and DWMH. (orig.)

  16. Age-related signal intensity changes in the corpus callosum: assessment with three orthogonal FLAIR images

    International Nuclear Information System (INIS)

    Yamamoto, Akira; Miki, Yukio; Kanagaki, Mitsunori; Takahashi, Takahiro; Fushimi, Yasutaka; Haque, Tabassum Laz; Togashi, Kaori; Tomimoto, Hidekazu; Konishi, Junya

    2005-01-01

    The presence of age-related hyperintensities of the corpus callosum has not been thoroughly evaluated. Fifty-two patients of 50 years of age or older (mean, 71 years; range, 50-87 years) were included in this study. Fluid-attenuated inversion recovery images were obtained in three orthogonal planes. Periventricular hyperintensities (PVHs) and deep white matter hyperintensities (DWMHs) were graded according to Fazekas' rating scale. Correlations between the presence of hyperintensities in the corpus callosum and age, and the grade of PVH and DWMH were statistically analyzed. PVH was categorized as grade 0 (n=4), grade 1 (n=28), grade 2 (n=10), or grade 3 (n=10). DWMH was categorized as grade 0 (n=4), grade 1 (n=25), grade 2 (n=8), or grade 3 (n=15). Hyperintensity was considered present in the corpus callosum in 31 of the 52 patients (60%). In these 31 patients, PVH was categorized as grade 1 (n=16), grade 2 (n=7), or grade 3 (n=8), while DWMH was categorized as grade 0 (n=1), grade 1 (n=10), grade 2 (n=7), or grade 3 (n=13). The presence of callosal hyperintensities was significantly correlated with age (p=0.001), and with PVH (p=0.04) and DWMH grades (p=0.004). Hyperintensities may be present in the corpus callosum with aging, and are correlated with PVH and DWMH. (orig.)

  17. Interhemispheric functional disconnection because of abnormal corpus callosum integrity in bipolar disorder type II.

    Science.gov (United States)

    Yasuno, Fumihiko; Kudo, Takashi; Matsuoka, Kiwamu; Yamamoto, Akihide; Takahashi, Masato; Nakagawara, Jyoji; Nagatsuka, Kazuyuki; Iida, Hidehiro; Kishimoto, Toshifumi

    2016-11-01

    A significantly lower fractional anisotropy (FA) value has been shown in anterior parts of the corpus callosum in patients with bipolar disorder. We investigated the association between abnormal corpus callosum integrity and interhemispheric functional connectivity (IFC) in patients with bipolar disorder. We examined the association between FA values in the corpus callosum (CC-FA) and the IFC between homotopic regions in the anterior cortical structures of bipolar disorder ( n =16) and major depressive disorder ( n =22) patients with depressed or euthymic states. We found a positive correlation between the CC-FA and IFC values between homotopic regions of the ventral prefrontal cortex and insula cortex, and significantly lower IFC between these regions in bipolar disorder patients. The abnormal corpus callosum integrity in bipolar disorder patients is relevant to the IFC between homotopic regions, possibly disturbing the exchange of emotional information between the cerebral hemispheres resulting in emotional dysregulation. None. © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.

  18. When "Safe" Means "Dangerous": A Corpus Investigation of Risk Communication in the Media

    Science.gov (United States)

    Tang, Chris; Rundblad, Gabriella

    2017-01-01

    The mass media has an important role in informing the general public about emerging health risks. Content-based studies of risk communication in the media have revealed a tendency to exaggerate risks or simplify science, but linguistic studies in this area are still scarce. This paper outlines a corpus based investigation of media reporting on the…

  19. Big Data, Big Questions: A Closer Look at the Yale–Classical Archives Corpus (c. 2015

    Directory of Open Access Journals (Sweden)

    Trevor deClerq

    2016-07-01

    Full Text Available This paper responds to the article by Christopher White and Ian Quinn, in which these authors introduce the Yale-Classical Archives Corpus (YCAC. I begin by making some general observations about the corpus, especially with regard to ramifications of the keyboard-performance origins of many pieces in the original MIDI collection. I then assess the accuracy of the scale-degree and local-key fields in the database, which were generated by the Bellman-Budge key-finding algorithm. I point out that some of the inaccuracies from the key-finding algorithm's output may influence the results we obtain from statistical studies of this corpus. I also offer an alternative analysis to the authors' finding that the ratio of V7 to V chords increases over time in common-practice music. Specifically, I conjecture that this finding may be the result of (or related to increasing instrumental resources over time. I close with some recommendations for future versions of the corpus, such as enabling end users to help repair transcription errors as well as offer ground truths for harmonic analyses and key area information.

  20. The subjective use of postural verbs in Afrikaans (II): a corpus ...

    African Journals Online (AJOL)

    Kate H

    Whereas the first article focused on the development of the postular .... 25. 2. Corpus discussion. Unfortunately, there are few Afrikaans corpora available .... In the third instance, it is assumed that the original meaning of the word influences the .... the extent to which they have become grammaticalised in terms of each other.

  1. Corpus-Aided Business English Collocation Pedagogy: An Empirical Study in Chinese EFL Learners

    Science.gov (United States)

    Chen, Lidan

    2017-01-01

    This study reports an empirical study of an explicit instruction of corpus-aided Business English collocations and verifies its effectiveness in improving learners' collocation awareness and learner autonomy, as a result of which is significant improvement of learners' collocation competence. An eight-week instruction in keywords' collocations,…

  2. A Corpus-Based Evaluation of Metaphors in a Business English Textbook

    Science.gov (United States)

    Skorczynska Sznajder, Hanna

    2010-01-01

    This study aims to evaluate the selection of metaphors in a published business English textbook using findings from a specialised corpus of written business English. While most scholars agree that metaphors should be included in English for Specific Purposes (ESP) syllabuses as a potentially problematic area in successful language learning, it is…

  3. Detection of Common Errors in Turkish EFL Students' Writing through a Corpus Analytic Approach

    Science.gov (United States)

    Demirel, Elif Tokdemir

    2017-01-01

    The present study aims to explore Turkish EFL students' major writing difficulties by analyzing the frequent writing errors in academic essays. Accordingly, the study examined errors in a corpus of 150 academic essays written by Turkish EFL students studying at the Department of English Language and Literature at a public university in Turkey. The…

  4. Methodological Flaws in Corpus-Based Studies on Malaysian ESL Textbooks

    Science.gov (United States)

    Zarifi, Abdolvahed; Mukundan, Jayakaran; Rezvani Kalajahi, Seyed Ali

    2014-01-01

    With the increasing interest among the pedagogy researchers in the use of corpus linguistics methodologies to study textbooks, there has emerged a similar enthusiasm among the materials developers to draw on empirical findings in the development of the state-of-the-art curricula and syllabi. In order for these research findings to have their…

  5. Corpus Callosum Size is Linked to Dichotic Deafness and Hemisphericity, Not Sex or Handedness

    Science.gov (United States)

    Morton, Bruce E.; Rafto, Stein E.

    2006-01-01

    Individuals differ in the number of corpus callosum (CC) nerve fibers interconnecting their cerebral hemispheres by about threefold. Early reports suggested that males had smaller CCs than females. This was often interpreted to support the concept that the male brain is more "lateralized" or "specialized," thus accounting for presumed male…

  6. The first Malay language storytelling text-to-speech (TTS) corpus for ...

    African Journals Online (AJOL)

    speech annotations are described in detail in accordance to baseline work. The stories were recorded in two speaking styles that are neutral and storytelling speaking style. The first. Malay language storytelling corpus is not only necessary for the development of a storytelling text-to-speech (TTS) synthesis. It is also ...

  7. Corpus callosum dysgenesis and lipoma: embryologic and magnetic resonance imaging aspects; Disgenesia do corpo caloso e lipoma: consideracoes embriologicas basicas e aspectos de imagem a ressonancia magnetica

    Energy Technology Data Exchange (ETDEWEB)

    Abreu Junior, Luiz de; Borri, Maria Lucia; Wolosker, Angela Maria Borri; Hartmann, Luiz Guilherme de Carvalho; Galvao Filho, Mario de Melo [Hospital e Maternidade Sao Luiz, Sao Paulo, SP (Brazil). Setor de Diagnostico por Imagem]. E-mail: abreujr@directnet.com.br; D' Ippolito, Giuseppe [Hospital e Maternidade Sao Luiz, Sao Paulo, SP (Brazil). Setor de US/TC/RMN

    2005-07-15

    The corpus callosum is the major system of association fibers that permits communication of both cerebral hemispheres. Magnetic resonance imaging has improved the study of brain malformations, including the corpus callosum dysgenesis. Lipoma is a common finding in the spectrum of corpus callosum dysgenesis. The purpose of these study was to review the embryologic events and the magnetic resonance imaging aspects related to the corpus callosum dysgenesis and to the formation of the related lipoma. (author)

  8. Human corpus luteum: presence of epidermal growth factor receptors and binding characteristics

    International Nuclear Information System (INIS)

    Ayyagari, R.R.; Khan-Dawood, F.S.

    1987-01-01

    Epidermal growth factor receptors are present in many reproductive tissues but have not been demonstrated in the human corpus luteum. To determine the presence of epidermal growth factor receptors and its binding characteristics, we carried out studies on the plasma cell membrane fraction of seven human corpora lutea (days 16 to 25) of the menstrual cycle. Specific epidermal growth factor receptors were present in human corpus luteum. Insulin, nerve growth factor, and human chorionic gonadotropin did not competitively displace epidermal growth factor binding. The optimal conditions for corpus luteum-epidermal growth factor receptor binding were found to be incubation for 2 hours at 4 degrees C with 500 micrograms plasma membrane protein and 140 femtomol 125 I-epidermal growth factor per incubate. The number (mean +/- SEM) of epidermal growth factor binding sites was 12.34 +/- 2.99 X 10(-19) mol/micrograms protein; the dissociation constant was 2.26 +/- 0.56 X 10(-9) mol/L; the association constant was 0.59 +/- 0.12 X 10(9) L/mol. In two regressing corpora lutea obtained on days 2 and 3 of the menstrual cycle, there was no detectable specific epidermal growth factor receptor binding activity. Similarly no epidermal growth factor receptor binding activity could be detected in ovarian stromal tissue. Our findings demonstrate that specific receptors for epidermal growth factor are present in the human corpus luteum. The physiologic significance of epidermal growth factor receptors in human corpus luteum is unknown, but epidermal growth factor may be involved in intragonadal regulation of luteal function

  9. BrAgriNews: Um Corpus Temporal-Causal (Português-Brasileiro para a Agricultura

    Directory of Open Access Journals (Sweden)

    Brett Drury

    2017-07-01

    Full Text Available Recentemente tem havido um aumento no interesse, tanto no meio acadêmico quanto na indústria, em aplicações de aprendizagem de máquina e técnicas de inteligência artificial relacionadas com problemas agrícolas. Mineração de texto e técnicas relacionadas com o processamento da língua natural, raramente foram usadas para resolver problemas agrícolas, e muito menos para a língua portuguesa. É possível que um dos fatores que influenciam a escassez no uso técnicas de mineração de texto, para analisar textos em português e resolver problemas agrícolas, pode ser devido à falta de um corpus anotado livremente disponível. Para colmatar a falta de um corpus agrícola em língua portuguesa, estamos liberando um recurso em português-brasileiro voltado para agricultura, descrito neste artigo. O corpus abrange um período parcialmente contínuo de tempo entre 1996 e 2016, consistindo de notícias em português-brasileiro que foram anotadas com o seguinte tipo de informação: causal, sentimento, entidades nomeadas que incluem expressões temporais. O corpus tem recursos adicionais como: treebank, listas de termos frequentes (sem stop-words: unigramas, bigramas e trigramas, bem como palavras ou frases que foram identificados por jornalistas como de domínio específico. Espera-se que a liberação do corpus estimule a adoção da mineração de texto na agricultura na comunidade de pesquisa lusófona.

  10. Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A2 with low catalytic activity from Bothrops jararacussu venom

    International Nuclear Information System (INIS)

    Corrêa, L. C.; Marchi-Salvador, D. P.; Cintra, A. C. O.; Soares, A. M.; Fontes, M. R. M.

    2006-01-01

    A myotoxic Asp49-PLA 2 with low catalytic activity from B. jararacussu (BthTX-II) was crystallized in the monoclinic crystal system; a complete X-ray diffraction data set was collected and a molecular-replacement solution was obtained. The oligomeric structure of BthTX-II resembles those of the Asp49-PLA 2 PrTX-III and all bothropic Lys49-PLA 2 s. For the first time, a complete X-ray diffraction data set has been collected from a myotoxic Asp49-phospholipase A 2 (Asp49-PLA 2 ) with low catalytic activity (BthTX-II from Bothrops jararacussu venom) and a molecular-replacement solution has been obtained with a dimer in the asymmetric unit. The quaternary structure of BthTX-II resembles the myotoxin Asp49-PLA 2 PrTX-III (piratoxin III from B. pirajai venom) and all non-catalytic and myotoxic dimeric Lys49-PLA 2 s. In contrast, the oligomeric structure of BthTX-II is different from the highly catalytic and non-myotoxic BthA-I (acidic PLA 2 from B. jararacussu). Thus, comparison between these structures should add insight into the catalytic and myotoxic activities of bothropic PLA 2 s

  11. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1{alpha} targeted gene expression

    Energy Technology Data Exchange (ETDEWEB)

    Miyake, Kotaro, E-mail: hif.panc@gmail.com [Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503 (Japan); Nishioka, Masanori; Imura, Satoru; Batmunkh, Erdenebulgan [Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503 (Japan); Uto, Yoshihiro [Department of Biological Science and Technology, Institute of Socio Technosciences, The University of Tokushima Graduate School, Tokushima 770-8503 (Japan); Nagasawa, Hideko [Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Gifu 501-1196 (Japan); Hori, Hitoshi [Department of Biological Science and Technology, Institute of Socio Technosciences, The University of Tokushima Graduate School, Tokushima 770-8503 (Japan); Shimada, Mitsuo [Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503 (Japan)

    2012-08-01

    Tumor hypoxia has been considered to be a potential therapeutic target, because hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. In the present study, we investigated the antitumor effect of a novel hypoxic cytotoxin, 3-[2-hydroxyethyl(methyl)amino]-2-quinoxalinecarbonitrile 1,4-dioxide (TX-2098) in inhibiting the expression of hypoxia inducible factor-1{alpha} (HIF-1{alpha}), and consequently vascular endothelial cell growth factor (VEGF) expression in pancreatic cancer. The antitumor effects of TX-2098 under hypoxia were tested against various human pancreatic cancer cell lines using WST-8 assay. VEGF protein induced pancreatic cancer was determined on cell-free supernatant by ELISA. Moreover, nude mice bearing subcutaneously (s.c.) or orthotopically implanted human SUIT-2 were treated with TX-2098. Tumor volume, survival and expression of HIF-1 and associated molecules were evaluated in treatment versus control groups. In vitro, TX-2098 inhibited the proliferation of various pancreatic cancer cell lines. In s.c model, tumors from nude mice injected with pancreatic cancer cells and treated with TX-2098 showed significant reductions in volume (P < 0.01 versus control). Quantitative real-time reverse transcription-PCR analysis revealed that TX-2098 significantly inhibited mRNA expression of the HIF-1 associated molecules, VEGF, glucose transporter 1 and Aldolase A (P < 0.01 versus control). These treatments also prolong the survival in orthotopic models. These results suggest that the effect of TX-2098 in pancreatic cancer might be correlated with the expression of VEGF and HIF-1 targeted molecules. -- Highlights: Black-Right-Pointing-Pointer We designed and synthesized novel hypoxic cytoxin, TX-2098. Black-Right-Pointing-Pointer TX-2098 inhibited the proliferation of human pancreatic cancer cells than TPZ. Black-Right-Pointing-Pointer TX-2098 reduced VEGF protein level than TPZ. Black-Right-Pointing-Pointer TX-2098

  12. The novel hypoxic cytotoxin, TX-2098 has antitumor effect in pancreatic cancer; possible mechanism through inhibiting VEGF and hypoxia inducible factor-1α targeted gene expression

    International Nuclear Information System (INIS)

    Miyake, Kotaro; Nishioka, Masanori; Imura, Satoru; Batmunkh, Erdenebulgan; Uto, Yoshihiro; Nagasawa, Hideko; Hori, Hitoshi; Shimada, Mitsuo

    2012-01-01

    Tumor hypoxia has been considered to be a potential therapeutic target, because hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. In the present study, we investigated the antitumor effect of a novel hypoxic cytotoxin, 3-[2-hydroxyethyl(methyl)amino]-2-quinoxalinecarbonitrile 1,4-dioxide (TX-2098) in inhibiting the expression of hypoxia inducible factor-1α (HIF-1α), and consequently vascular endothelial cell growth factor (VEGF) expression in pancreatic cancer. The antitumor effects of TX-2098 under hypoxia were tested against various human pancreatic cancer cell lines using WST-8 assay. VEGF protein induced pancreatic cancer was determined on cell-free supernatant by ELISA. Moreover, nude mice bearing subcutaneously (s.c.) or orthotopically implanted human SUIT-2 were treated with TX-2098. Tumor volume, survival and expression of HIF-1 and associated molecules were evaluated in treatment versus control groups. In vitro, TX-2098 inhibited the proliferation of various pancreatic cancer cell lines. In s.c model, tumors from nude mice injected with pancreatic cancer cells and treated with TX-2098 showed significant reductions in volume (P < 0.01 versus control). Quantitative real-time reverse transcription-PCR analysis revealed that TX-2098 significantly inhibited mRNA expression of the HIF-1 associated molecules, VEGF, glucose transporter 1 and Aldolase A (P < 0.01 versus control). These treatments also prolong the survival in orthotopic models. These results suggest that the effect of TX-2098 in pancreatic cancer might be correlated with the expression of VEGF and HIF-1 targeted molecules. -- Highlights: ► We designed and synthesized novel hypoxic cytoxin, TX-2098. ► TX-2098 inhibited the proliferation of human pancreatic cancer cells than TPZ. ► TX-2098 reduced VEGF protein level than TPZ. ► TX-2098 inhibited mRNA expression of VEGF, GLUT1 and Aldolase A, not HIF-1α. ► TX-2098 improved the survival in

  13. Programa Nordeste para transplante cardiaco "NE-Tx": experiência atual NE-Tx North East Brazil heart transplant program: current-experience

    Directory of Open Access Journals (Sweden)

    Ricardo Lima

    1992-09-01

    Full Text Available Os autores relatam a presente experiência clínica do programa NE-Tx, que é integrado por quatro diferentes Centros, bem como suas peculiaridades regionais. Foi idealizado um programa com baixo custo e integração regional. Na investigação pré-operatória, foi valorizado o nível social e intelectual do receptor e sua relação com os familiares. A busca de órgão à distância foi suprimida, com o deslocamento do receptor até o local da disponibilidade do órgáo. No pós-operatório não se utilizou dosagem sérica de ciclosporina, tendo os pacientes sido controlados com monitorização seriada da função renal. Com essa estratégia, foram operados 7 pacientes, no período compreendido entre 19.7.86 e 1.11.91., em três diferentes Centros Integrados. Todos eram do sexo masculino e a idade variou de 17 a 50 anos. Três (42,8% pacientes eram portadores de miocardiopatiachagásica, 2 (28,5% de miocardiopatiaidiopática, 1 (14,3% de miocardiopatia hipertrófica e 1 (14,3% de miocardiopatia reumática. Três (42,8% pacientes vieram de Centros diferentes: 1 de Natal para Recife, 1 de Maceió para Aracaju e um terceiro de Aracaju para Maceió. Dois (28,6% pacientes faleceram: um no período de pós-operatório imediato, de maneira ignorada e outro no pós-operatório tardio, devido a crise de rejeição. A mortalidade imediata foi de 14,3% e a tardia de 14,3%. Os restantes 5 (71,4% pacientes encontram-se evoluindo bem, tendo o follow-up variado de 2 a 48 meses. A incidência de infecção, rejeição e demais problemas relacionados com o pós-operatório tardio é superponível com outros Centros. O programa mostrou-se eficiente, prático, compatível com nossa realidade e reproduz resultados de outras experiências.The authors report their current clinical experience with the "NE-Tx" program, which covers four different centres, as well as its regional peculiarities. The program was designed to be of low cost and regionally integrated. In

  14. Disregarding the Corpus: Head-word and Sense Treatment in Shona Monolingual Lexicography*

    Directory of Open Access Journals (Sweden)

    Webster M. Mavhu

    2011-10-01

    Full Text Available

    Abstract: With specific reference to Shona monolingual lexicography, this article discusses how corpus-based lexicographers might, in some instances, decide not strictly to adhere to the corpus when it comes to headword and sense treatment. The writer is a member of the African Languages Research Institute (ALRI, formerly known as the African Languages Lexical (ALLEX Project. ALRI is a nonfaculty interdisciplinary unit dedicated to research on and the development of African languages in Zimbabwe. The writer is part of the six-member team that compiled the now published Shona monolingual, synchronic, medium-sized and general-purpose dictionary Du-ramazwi Guru ReChiShona (2001. The article originates from the writer's experience of working on this dictionary. The article highlights the fact that being corpus-based does not necessarily imply being corpus-bound.

    Keywords: CORPUS, CORPUS-BASED, FREQUENCY, HEADWORD, LEXICOGRAPHY, SENSE, SHONA, SLANG, SYNONYMS

    Opsomming: Verontagsaming van die korpus: Trefwoord- en betekenisbe-handeling in die Sjona- eentalige leksikografie. Met spesifieke verwysing na die Sjona- eentalige leksikografie bespreek hierdie artikel hoe korpusgebaseerde leksikograwe in som-mige gevalle kan besluit om nie streng by die korpus te bly wanneer dit kom by trefwoord- en betekenisbehandeling nie. Die skrywer is 'n lid van die African Language Research Institute (AL-RI, vroeër bekend as die African Languages Lexical (ALLEX Project. ALRI is 'n niefakulteits- interdissiplinêre eenheid wat hom beywer vir navorsing oor en die ontwikkeling van die Afrikatale in Zimbabwe. Die skrywer is deel van 'n span van ses lede wat die reeds gepubliseerde Sjona- een-talige, sinchroniese, middelgroot en meerdoelige woordeboek Duramazwi Guru ReChiShona (2001 saamgestel het. Die artikel het uit die skrywer se ervaring van werk aan hierdie woordeboek ont-staan. Die artikel belig die feit dat korpusgebaseerdheid nie noodwendig

  15. TX 2000: total reflection and 45o energy dispersive x-ray fluorescence spectrometer

    International Nuclear Information System (INIS)

    Pasti, F.; Torboli, A.; Valdes, M.

    2000-01-01

    This equipment, developed by Ital Structures, combines two kinds of energy dispersive X-ray fluorescence techniques, the first using total reflection geometry and the second conventional 45 o geometry. The equipment is completely controlled by a PC and to reach the condition of total reflection is very easy because it is enough to load the file with the right position for the corresponding energy. In this apparatus we used an x-ray tube with an alloy anode of Mo/W with a long fine focus at 2200 W. To monochromatize the x-ray beam while choosing, for example, the Mo K alpha or W L alpha or a piece of white spectrum of 33 keV, we use a highly reflective multilayer made of Si/W with 2d = 45.5 A o . The detector used in the equipment is a lithium drifted silicon detector (Si(Li)) with an excellent energy resolution of 135 eV at 5.9 keV and 1000 cps. We developed two programs written in Windows 95, 98 and NT for a 32 bit microprocessor. The first one is called TYACQ32 and has the following functions: first, complete control of the hardware, second automatic alignment of the TX 2000 spectrometer and third acquisition of spectra. The second program is EDXRF32. This is a program to accomplish spectrum and quantitative analysis for TXRF and EDXRF 45 o degrees analysis. (author)

  16. Occupational exposure to benzene at the ExxonMobil refinery in Baytown, TX (1978-2006).

    Science.gov (United States)

    Gaffney, Shannon H; Panko, Julie M; Unice, Ken M; Burns, Amanda M; Kreider, Marisa L; Gelatt, Richard H; Booher, Lindsay E; Paustenbach, Dennis J

    2011-01-01

    Although occupational benzene exposure of refinery workers has been studied for decades, no extensive analysis of historical industrial hygiene data has been performed focusing on airborne concentrations at specific refineries and tasks. This study characterizes benzene exposures at the ExxonMobil Baytown, TX, refinery from 1978 to 2006 to understand the variability in workers' exposures over time and during different job tasks. Exposures were grouped by operational status, job title, and tasks. More than 9000 industrial hygiene air samples were evaluated; approximately 4000 non-task (> 3 h) and 1000 task-related (work areas, and 16 task bins (when applicable). Process technicians were sampled most frequently, resulting in the following mean benzene concentrations by area: hydrofiner (n=245, mean=1.3 p.p.m.), oil movements (n=286, mean=0.23 p.p.m.), reformer (n=575, mean=0.10 p.p.m.), tank farm (n=9, mean=0.65 p.p.m.), waste treatment (n=446, mean=0.13 p.p.m.), and other areas (n=460, mean=0.062 p.p.m.). The most frequently sampled task was sample collection (n=218, mean=0.40 p.p.m.). Job title and area did not significantly impact task-related exposures. Airborne concentrations were significantly lower after 1990 than before 1990. Results of this task-focused study may be useful when analyzing benzene exposures at other refineries.

  17. [Comparative study between the non-contact pneumotonometer Canon TX10 and the Goldmann tonometer].

    Science.gov (United States)

    Sánchez-Tocino, H; Bringas-Calvo, R; Iglesias-Cortiñas, D

    2005-11-01

    To study and contrast the measurement of intraocular pressure (IOP) with an air non-contact tonometer (Canon TX-10) with that obtained with the Goldmann tonometer. Intraocular pressure was measured in 649 subjects with both the pneumotonometer and the Goldmann tonometer. Statistically significant differences between the results obtained by both tonometers and the influence of variables including age, corneal thickness, and corneal curvature were studied. The mean age of the study population was 48.5 years, standard deviation (SD) 7.6 years, with a range of 22-68 years. The mean IOP was 15.4, SD 2.7 mm Hg, (range 8-25) with the Goldmann tonometer and 15.6, SD 2.9 mm Hg (range 8-29) with the pneumotonometer. There was a statistically significant difference between the measurements using the air pneumotonometer and the Goldmann tonometer (ptonometers was 0.24, SD 2 mm Hg. Seventy-five percent of measurements were in the range of +/-1, 85% in +/-2, and 95% in the Bland and Altman's interval of 4.42, -3.94. These differences were more significant for higher values of IOP, in thicker corneas and in corneas with greater curvature. A correlation between IOP and age was not found (p=0.247). The pneumotonometer is a useful and reliable instrument for measuring the IOP providing there is additional checking in cases with borderline values of IOP, or excessive corneal thickness and/or curvature.

  18. Reservoir fracture mapping using microearthquakes: Austin chalk, Giddings field, TX and 76 field, Clinton Co., KY

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, W.S.; Rutledge, J.T.; Gardner, T.L. [SPE, Richardson, TX (United States); Fairbanks, T.D.; Miller, M.E.; Schuessler, B.K. [Los Alamos National Lab., NM (United States)

    1996-11-01

    Patterns of microearthquakes detected downhole defined fracture orientation and extent in the Austin chalk, Giddings field, TX and the 76 field, Clinton Co., KY. We collected over 480 and 770 microearthquakes during hydraulic stimulation at two sites in the Austin chalk, and over 3200 during primary production in Clinton Co. Data were of high enough quality that 20%, 31% and 53% of the events could be located, respectively. Reflected waves constrained microearthquakes to the stimulated depths at the base of the Austin chalk. In plan view, microearthquakes defined elongate fracture zones extending from the stimulation wells parallel to the regional fracture trend. However, widths of the stimulated zones differed by a factor of five between the two Austin chalk sites, indicating a large difference in the population of ancillary fractures. Post-stimulation production was much higher from the wider zone. At Clinton Co., microearthquakes defined low-angle, reverse-fault fracture zones above and below a producing zone. Associations with depleted production intervals indicated the mapped fractures had been previously drained. Drilling showed that the fractures currently contain brine. The seismic behavior was consistent with poroelastic models that predicted slight increases in compressive stress above and below the drained volume.

  19. Test plan for headspace gas concentration measurement and headspace ventilation rate measurement for DCRTs 241-A-244, 241-BX-244, 241-S-244, 241-TX-244

    International Nuclear Information System (INIS)

    Bauer, R.E.

    1998-01-01

    This test plan provides the directions to characterize the headspace gas concentrations and the headspace ventilation rate for double contained receiver tanks 241-A-244, 241-BX-244, 241-S-244, and 241-TX-244

  20. 0-6759 : developing a business process and logical model to support a tour-based travel demand model design for TxDOT.

    Science.gov (United States)

    2013-08-01

    The Texas Department of Transportation : (TxDOT) created a standardized trip-based : modeling approach for travel demand modeling : called the Texas Package Suite of Travel Demand : Models (referred to as the Texas Package) to : oversee the travel de...