WorldWideScience

Sample records for core aims progress

  1. Advanced Industrial Materials (AIM) Program: Annual progress report FY 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    In many ways, the Advanced Industrial Materials (AIM) Program underwent a major transformation in Fiscal Year 1995 and these changes have continued to the present. When the Program was established in 1990 as the Advanced Industrial Concepts (AIC) Materials Program, the mission was to conduct applied research and development to bring materials and processing technologies from the knowledge derived from basic research to the maturity required for the end use sectors for commercialization. In 1995, the Office of Industrial Technologies (OIT) made radical changes in structure and procedures. All technology development was directed toward the seven ``Vision Industries`` that use about 80% of industrial energy and generated about 90% of industrial wastes. The mission of AIM has, therefore, changed to ``Support development and commercialization of new or improved materials to improve productivity, product quality, and energy efficiency in the major process industries.`` Though AIM remains essentially a National Laboratory Program, it is essential that each project have industrial partners, including suppliers to, and customers of, the seven industries. Now, well into FY 1996, the transition is nearly complete and the AIM Program remains reasonably healthy and productive, thanks to the superb investigators and Laboratory Program Managers. This Annual Report for FY 1995 contains the technical details of some very remarkable work by the best materials scientists and engineers in the world. Areas covered here are: advanced metals and composites; advanced ceramics and composites; polymers and biobased materials; and new materials and processes.

  2. Advanced Industrial Materials (AIM) Program annual progress report, FY 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    The Advanced Industrial Materials (AIM) Program is a part of the Office of Industrial Technologies (OIT), Energy Efficiency and Renewable Energy, US Department of Energy (DOE). The mission of AIM is to support development and commercialization of new or improved materials to improve energy efficiency, productivity, product quality, and reduced waste in the major process industries. OIT has embarked on a fundamentally new way of working with industries--the Industries of the Future (IOF) strategy--concentrating on the major process industries that consume about 90% of the energy and generate about 90% of the waste in the industrial sector. These are the aluminum, chemical, forest products, glass, metalcasting, and steel industries. OIT has encouraged and assisted these industries in developing visions of what they will be like 20 or 30 years into the future, defining the drivers, technology needs, and barriers to realization of their visions. These visions provide a framework for development of technology roadmaps and implementation plans, some of which have been completed. The AIM Program supports IOF by conducting research and development on materials to solve problems identified in the roadmaps. This is done by National Laboratory/industry/university teams with the facilities and expertise needed to develop new and improved materials. Each project in the AIM Program has active industrial participation and support.

  3. The Core of Religious Education: Finnish Student Teachers' Pedagogical Aims

    Science.gov (United States)

    Kuusisto, Elina; Tirri, Kirsi

    2014-01-01

    This article investigated the core of religious education (RE) by examining Finnish student teachers' pedagogical aims in the context of Lutheran RE. The data consisted of essays (N=82) analysed in a deductive manner using the main concepts of the didactic triangle together with the aims of the Finnish National Core Curriculum. The student…

  4. A tale of three theories: Feyerabend and Popper on progress and the aim of science.

    Science.gov (United States)

    Tambolo, Luca

    2015-06-01

    In this paper, three theories of progress and the aim of science are discussed: (i) the theory of progress as increasing explanatory power, advocated by Popper in The logic of scientific discovery (1935/1959); (ii) the theory of progress as approximation to the truth, introduced by Popper in Conjectures and refutations (1963); (iii) the theory of progress as a steady increase of competing alternatives, which Feyerabend put forward in the essay "Reply to criticism. Comments on Smart, Sellars and Putnam" (1965) and defended as late as the last edition of Against method (1993). It is argued that, contrary to what Feyerabend scholars have predominantly assumed, Feyerabend's changing attitude towards falsificationism-which he often advocated at the beginning of his career, and vociferously attacked in the 1970s and 1980s-must be explained by taking into account not only Feyerabend's very peculiar view of the aim of science, but also Popper's changing account of progress.

  5. Labview based testing system for the aim of construction of energy efficient magnetic cores

    Directory of Open Access Journals (Sweden)

    Pluta Wojciech

    2017-01-01

    The paper presents an example of an application for testing the system based on Labview platform for quality checking of large magnetic cores in the order of 1000 kg. Example of testing data for one and three phase core are presented.

  6. [Aims and core contents of basic and post basic courses of nursing management].

    Science.gov (United States)

    Saiani, Luisa; Brugnolli, Anna

    2006-01-01

    The second part of the issue, dedicated to the nursing management offers a discussion on some of the relevant areas of debate for the organization of nursing care. A reflection on the core contents and main aims of basic and post basic (master, advanced level, specialistic degree) nursing courses is proposed in the first contribution. Then a selection of topics is presented, focusing on the main research contributions available in the literature and on the ongoing debate for the following areas: the role of communication at the inter-shift handover and the new model of bedside reporting; the problems and challenges of doctors nurses collaboration in the health care team; the problems and expectations of new nurses joining the health care team and the process of development of practical skills; the hot debate on nursing roles and level of practice and the difficulties in differentiating between elementary, specialist and advanced nursing practice; the new emerging roles: the characteristics and achievements of Nurse Consultant; the new challenges of coordinators of the health care teams with the management of the multigenerational nursing team. For each topic a definition of the problem is presented, an example of relevant study, a critical debate and suggestions for further studies and areas of research. A list of the main journals that deal with nursing management is proposed with comments on the main characteristics of each journal. A study protocol that aims at describing the outcomes of the different styles and models of organization of medical wards on patients and nurses is presented as an example of organizative research; an experience of, and a model for, participation of the nurses to health policy planning is proposed. Nurses were, asked to identify health care problems encountered in their daily practice, their causes and propose solutions at basic and policy level. The session of International Observatory explores the main problems and difficulties of

  7. Core English KS3 real progress in reading

    CERN Document Server

    Belsey, David; Page, Emma

    2014-01-01

    Real Progress in Reading shares the core knowledge and skills that successful readers use in order to appreciate, understand and critically read a wide range of texts. Aligned to the new National Curriculum for English and with progression built into each unit, this book helps students to build a firm foundation in reading. Contents include:. - How to identify audience and purpose of texts. - How to select evidence from texts. - How to compare texts. - How to analyse features of form, structure and presentation.

  8. Progress of MCT Detector Technology at AIM Towards Smaller Pitch and Lower Dark Current

    Science.gov (United States)

    Eich, D.; Schirmacher, W.; Hanna, S.; Mahlein, K. M.; Fries, P.; Figgemeier, H.

    2017-09-01

    We present our latest results on cooled p-on- n planar mercury cadmium telluride (MCT) photodiode technology. Along with a reduction in dark current for raising the operating temperature ( T op), AIM INFRAROT-MODULE GmbH (AIM) has devoted its development efforts to shrinking the pixel size. Both are essential requirements to meet the market demands for reduced size, weight and power and high-operating temperature applications. Detectors based on the p-on- n technology developed at AIM now span the spectrum from the mid-wavelength infrared (MWIR) to the very long wavelength infrared (VLWIR) with cut-off wavelengths from 5 μm to about 13.5 μm at 80 K. The development of the p-on- n technology for VLWIR as well as for MWIR is mainly implemented in a planar photodetector design with a 20- μm pixel pitch. For the VLWIR, dark currents significantly reduced as compared to `Tennant's Rule 07' are demonstrated for operating temperatures between 30 K and 100 K. This allows for the same dark current performance at a 20 K higher operating temperature than with previous AIM technology. For MWIR detectors with a 20- μm pitch, noise equivalent temperature differences of less than 30 mK are obtained up to 170 K. This technology has been transferred to our small pixel pitch high resolution (XGA) MWIR detector with 1024 × 768 pixels at a 10- μm pitch. Excellent performance at an operating temperature of 160 K is demonstrated.

  9. Alzheimer's Disease Neuroimaging Initiative 2 Clinical Core: Progress and plans.

    Science.gov (United States)

    Aisen, Paul S; Petersen, Ronald C; Donohue, Michael; Weiner, Michael W

    2015-07-01

    This article reviews the current status of the Clinical Core of the Alzheimer's Disease Neuroimaging Initiative (ADNI), and summarizes planning for the next stage of the project. Clinical Core activities and plans were synthesized based on discussions among the Core leaders and external advisors. The longitudinal data in ADNI-2 provide natural history data on a clinical trials population and continue to inform refinement and standardization of assessments, models of trajectories, and clinical trial methods that have been extended into sporadic preclinical Alzheimer's disease (AD). Plans for the next phase of the ADNI project include maintaining longitudinal follow-up of the normal and mild cognitive impairment cohorts, augmenting specific clinical cohorts, and incorporating novel computerized cognitive assessments and patient-reported outcomes. A major hypothesis is that AD represents a gradually progressive disease that can be identified precisely in its long presymptomatic phase, during which intervention with potentially disease-modifying agents may be most useful. Copyright © 2015 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  10. EVIDENCE BASED PROGRESSIVE CORE STABILIZATION EXERCISE FORMATION FOR LOW CORE ENDURANCE INDIVIDUALS

    Directory of Open Access Journals (Sweden)

    Kulandaivelan.S

    2014-06-01

    Full Text Available Low back pain (LBP is the commonest pain among individuals affecting more than half of the population. Segmental stabilization exercises gaining popularity among many treatment choices available to the therapist. Transverses abdominis (TA and Multifidi (MF are the two core muscles that were affected by LBP. This descriptive partial review study examines how various exercises recruits TA and MF? Then how do one to prognoses them progressively over short period of time? And what is the dose, volume needed? This review put an attempt to solve the above questions based on recent evidence based practice. Finally we have given exercise schedule for physiotherapists to follow.

  11. FY13 Annual Progress Report for SECA Core Technology Program

    Energy Technology Data Exchange (ETDEWEB)

    Stevenson, Jeffry W.; Koeppel, Brian J.

    2014-01-31

    This progress report covers technical work performed during fiscal year 2013 at PNNL under Field Work Proposal (FWP) 40552. The report highlights and documents technical progress in tasks related to advanced cell and stack component materials development and computational design and simulation. Primary areas of emphasis for the materials development work were metallic interconnects and coatings, cathode and anode stability/degradation, glass seals, and advanced testing under realistic stack conditions: Metallic interconnects and coatings • Effects of surface modifications to AISI 441 (prior to application of protective spinel coatings) on oxide scale growth and adhesion were evaluated as a function of temperature and time. Cathode stability/degradation • Effects of cathode air humidity on performance and stability of SOFC cathodes were investigated by testing anode-supported cells as a function of time and temperature. • In-situ high temperature XRD measurements were used to correlate changes in cathode lattice structure and composition with performance of anode-supported button cells. Anode stability/degradation • Effects of high fuel steam content on Ni/YSZ anodes were investigated over a range of time and temperature. • Vapor infiltration and particulate additions were evaluated as a potential means of improving tolerance of Ni/YSZ anodes to sulfur-bearing fuel species. Glass seals • A candidate compliant glass-based seal materials were evaluated in terms of microstructural evolution and seal performance as a function of time and temperature. Stack fixture testing • The SECA CTP stack test fixture was used for intermediate and long-term evaluation of candidate materials and processes. Primary areas of emphasis for the computational modeling work were coarse methodology, degradation of stack components, and electrochemical modeling: Coarse methodology • Improvements were made to both the SOFC-MP and SOFC ROM simulation tools. Degradation of stack

  12. The National United States Center Data Repository: Core essential interprofessional practice & education data enabling triple aim analytics

    Science.gov (United States)

    Pechacek, Judith; Shanedling, Janet; Lutfiyya, May Nawal; Brandt, Barbara F.; Cerra, Frank B.; Delaney, Connie White

    2015-01-01

    Abstract Understanding the impact that interprofessional education and collaborative practice (IPECP) might have on triple aim patient outcomes is of high interest to health care providers, educators, administrators, and policy makers. Before the work undertaken by the National Center for Interprofessional Practice and Education at the University of Minnesota, no standard mechanism to acquire and report outcome data related to interprofessional education and collaborative practice and its effect on triple aim outcomes existed. This article describes the development and adoption of the National Center Data Repository (NCDR) designed to capture data related to IPECP processes and outcomes to support analyses of the relationship of IPECP on the Triple Aim. The data collection methods, web-based survey design and implementation process are discussed. The implications of this informatics work to the field of IPECP and health care quality and safety include creating standardized capacity to describe interprofessional practice and measure outcomes connecting interprofessional education and collaborative practice to the triple aim within and across sites/settings, leveraging an accessible data collection process using user friendly web-based survey design to support large data scholarship and instrument testing, and establishing standardized data elements and variables that can potentially lead to enhancements to national/international information system and academic accreditation standards to further team-based, interprofessional, collaborative research in the field. PMID:26652631

  13. A study on the late core melt progression in pressurized water reactor severe accidents

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae Hong; Jeun Gyoo Dong; Bang, Kwang Hyun; Park, Seh In; Lim, Jae Hyuck; Park, Seong Yong [Hanyang Univ., Seoul (Korea, Republic of); Back, Hyung Hmm [Korea Maritime Univ., Busan (Korea, Republic of)

    1998-03-15

    After TMI-2 accidents, it has been paid much attention to severe accidents beyond the design basis accidents and the research on the progress of severe accidents and mitigation and the closure of severe accidents has been actively performed. In particular, a great deal of uncertainties yet exist in the phase of late core melt progression and thus the research on this phase of severe accident progress has a key role in obtaining in severe accident mitigation and nuclear reactor safety. In the present study, physics of late core melt progression, experimental data and the major phenomenological models of computer codes are reviewed and a direction of reducing the uncertainties in the late core melt progression os proposed.

  14. Progress towards accelerating HOMME on hybrid multi- core systems

    Energy Technology Data Exchange (ETDEWEB)

    Archibald, Richard K [ORNL; Carpenter, Ilene L [ORNL; Evans, Katherine J [ORNL; Larkin, Jeff [Cray, Inc.; Micikevicius, Paulius [ORNL; Rosinski, James [NOAA, Boulder, CO; Schwarzmeier, James L [ORNL; Taylor, Mark [Sandia National Laboratories (SNL)

    2011-01-01

    The suitability of a spectral element based dynamical core (HOMME) within the Community Atmospheric Model (CAM) for GPU-based architectures is examined and initial performance results are reported. This work was done within a project to enable CAM to run at high resolution on next generation, multi-petaflop systems. The dynamical core is the present focus because it dominates the performance profile of our target problem. HOMME enjoys good scalability due to its underlying cubed-sphere mesh with full two-dimensional decomposition and the localization of all computational work within each element. The thread blocking and code changes that allow HOMME to effectively use GPUs are described along with a rewritten vertical remapping scheme which improves performance on both CPUs and GPUs. Validation of results in the full HOMME model is also described. Remaining issues affecting performance include optimizing the boundary exchanges for the case of multiple spectral elements being computed on the GPU and using multiple CUDA streams to overlap data transfers with computations.

  15. Recent Progress on Ascertaining the Core Collapse Supernova Explosion Mechanism

    CERN Document Server

    Mezzacappa, Anthony; Lentz, Eric J; Hix, W Raphael; Harris, J Austin; Messer, O E Bronson; Endeve, Eirik; Chertkow, Merek A; Blondin, John M; Marronetti, Pedro; Yakunin, Konstantin N

    2015-01-01

    We have been working within the fundamental paradigm that core collapse supernovae (CCSNe) may be neutrino driven, since the first suggestion of this by Colgate and White nearly five decades ago. Computational models have become increasingly sophisticated, first in one spatial dimension assuming spherical symmetry, then in two spatial dimensions assuming axisymmetry, and now in three spatial dimensions with no imposed symmetries. The increase in the number of spatial dimensions has been accompanied by an increase in the physics included in the models, and an increase in the sophistication with which this physics has been modeled. Computation has played an essential role in the development of CCSN theory, not simply for the obvious reason that such multidimensional, multi-physics, nonlinear events cannot possibly be fully captured analytically, but for its role in discovery. In particular, the discovery of the standing accretion shock instability (SASI) through computation about a decade ago has impacted all s...

  16. Aims & Scope

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    Asian Pacific Journal of Tropical Biomedicine(APJTB)aims to set up and provide an international academic communication platform for physicians,medical scientists,allied health scientists and public health workers,especially those in the Asian Pacific region and worldwide on tropical biomedicine,infectious diseases and public health,and to meet the growing challenges

  17. Aims & Scope

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    <正>Asian Pacific Journal of Tropical Biomedicine(APJTB)aims to set up and provide an international academic communication platform for physicians,medical scientists,allied health scientists and public health workers,especially those in the Asian Pacific region and worldwide on tropical biomedicine,infectious diseases and public health,and to meet the growing challenges of understanding,preventing and controlling the dramatic global emergence and reemergence of infectious diseases in the Asian Pacific region.

  18. Aims & Scope

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Asian Pacific Journal of Tropical Biomedicine(APJTB)aims to set up and provide an international academic communication platform for physicians,medical scientists,allied health scientists and public health workers,especially those in the Asian Pacific region and worldwide on tropical biomedicine,infectious diseases and public health,and to meet the growing challenges of understanding,preventing and controlling the dramatic global emergence and reemergence of infectious diseases in the Asian Pacific region.

  19. Evaluating core technology capacity based on an improved catastrophe progression method: the case of automotive industry

    Science.gov (United States)

    Zhao, Shijia; Liu, Zongwei; Wang, Yue; Zhao, Fuquan

    2017-01-01

    Subjectivity usually causes large fluctuations in evaluation results. Many scholars attempt to establish new mathematical methods to make evaluation results consistent with actual objective situations. An improved catastrophe progression method (ICPM) is constructed to overcome the defects of the original method. The improved method combines the merits of the principal component analysis' information coherence and the catastrophe progression method's none index weight and has the advantage of highly objective comprehensive evaluation. Through the systematic analysis of the influencing factors of the automotive industry's core technology capacity, the comprehensive evaluation model is established according to the different roles that different indices play in evaluating the overall goal with a hierarchical structure. Moreover, ICPM is developed for evaluating the automotive industry's core technology capacity for the typical seven countries in the world, which demonstrates the effectiveness of the method.

  20. Heave Compensated GLAD800 Coring from the R/V Knorr: a Progress Report

    Science.gov (United States)

    Nielson, D.; Mountain, G.; Pardey, M.; Austin, J.; Alexander, C.

    2001-12-01

    Despite potential applications to studies of stratal architecture, sea-level history, land-sea interaction, and rapid climate change, scientific drilling with high core recovery in shallow marine settings has been thwarted by several challenges. Among these has been the problem of maintaining hole stability while penetrating unconsolidated lithologies from a floating, open-ocean platform. We report on progress in overcoming this barrier. The GLAD800 coring system, originally developed as a joint venture between the International Scientific Drilling Program and DOSECC to collect long, high-resolution cores in modern lakes, has been adapted for deploying from the R/V Knorr. As in lake-based operations, the drilling system can continuously sample sediments of different composition and stiffness to a total depth of 800m below the rig floor using HWT drill rods and riser pipe. Core is collected in standard ODP-size plastic liners. A modular design provides inexpensive and easily transportable operations. The latest advance is the installation of an active heave compensation (AHC) system that accommodates as much as 8 feet of vertical rig motion. This minimizes excursions in the total weight of the bit at the cutting face, a major concern in achieving the high core recovery needed for scientific purposes. We show results of testing this AHC-equipped GLAD800 rig during a 5-day operation in November. We drilled through the existing 'moon pool' of the R/V Knorr on the outer shelf south of Martha's Vineyard. This technological development and ship time is funded by the Office of Naval Research, and if successful, will be extended to core numerous drill holes 10's to 100's of meters into the New Jersey shelf during 2002.

  1. Progress in hollow core photonic crystal fiber for atomic vapour based coherent optics

    Science.gov (United States)

    Bradley, T. D.; Wang, Y. Y.; Alharbi, M.; Fourcade Dutin, C.; Mangan, B. J.; Wheeler, N. V.; Benabid, F.

    2012-03-01

    We report on progress in different hollow core photonic crystal fiber (HC-PCF) design and fabrication for atomic vapor based applications. We have fabricated a Photonic bandgap (PBG) guiding HC-PCF with a record loss of 107dB/km at 785nm in this class of fiber. A double photonic bandgap (DPBG) guiding HC-PCF with guidance bands centred at 780nm and 1064nm is reported. A 7-cell 3-ring Kagome HC-PCF with hypocycloid core is reported, the optical loss at 780nm has been reduced to 70dB/km which to the best of our knowledge is the lowest optical loss reported at this wavelength using HC-PCF. Details on experimental loading of alkali metal vapours using a far off red detuned laser are reported. This optical loading has been shown to decrease the necessary loading time for Rb into the hollow core of a fiber. The quantity of Rb within the fiber core has been enhanced by a maximum of 14% through this loading procedure.

  2. Effect of Lumbar Progressive Resistance Exercise on Lumbar Muscular Strength and Core Muscular Endurance in Soldiers.

    Science.gov (United States)

    Mayer, John M; Childs, John D; Neilson, Brett D; Chen, Henian; Koppenhaver, Shane L; Quillen, William S

    2016-11-01

    Low back pain is common, costly, and disabling for active duty military personnel and veterans. The evidence is unclear on which management approaches are most effective. The purpose of this study was to assess the effectiveness of lumbar extensor high-intensity progressive resistance exercise (HIPRE) training versus control on improving lumbar extension muscular strength and core muscular endurance in soldiers. A randomized controlled trial was conducted with active duty U.S. Army Soldiers (n = 582) in combat medic training at Fort Sam Houston, Texas. Soldiers were randomized by platoon to receive the experimental intervention (lumbar extensor HIPRE training, n = 298) or control intervention (core stabilization exercise training, n = 284) at one set, one time per week, for 11 weeks. Lumbar extension muscular strength and core muscular endurance were assessed before and after the intervention period. At 11-week follow-up, lumbar extension muscular strength was 9.7% greater (p = 0.001) for HIPRE compared with control. No improvements in core muscular endurance were observed for HIPRE or control. Lumbar extensor HIPRE training is effective to improve isometric lumbar extension muscular strength in U.S. Army Soldiers. Research is needed to explore the clinical relevance of these gains. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

  3. The explosion mechanism of core-collapse supernovae: progress in supernova theory and experiments

    CERN Document Server

    Foglizzo, Thierry; Guilet, Jérôme; Masset, Frédéric; González, Matthias; Krueger, Brendan K; Novak, Jérôme; Oertel, Micaela; Margueron, Jérôme; Faure, Julien; Martin, Noël; Blottiau, Patrick; Peres, Bruno; Durand, Gilles

    2015-01-01

    The explosion of core-collapse supernova depends on a sequence of events taking place in less than a second in a region of a few hundred kilometers at the center of a supergiant star, after the stellar core approaches the Chandrasekhar mass and collapses into a proto-neutron star, and before a shock wave is launched across the stellar envelope. Theoretical efforts to understand stellar death focus on the mechanism which transforms the collapse into an explosion. Progress in understanding this mechanism is reviewed with particular attention to its asymmetric character. We highlight a series of successful studies connecting observations of supernova remnants and pulsars properties to the theory of core-collapse using numerical simulations. The encouraging results from first principles models in axisymmetric simulations is tempered by new puzzles in 3D. The diversity of explosion paths and the dependence on the pre-collapse stellar structure is stressed, as well as the need to gain a better understanding of hydr...

  4. Evolution of EDFA from single-core to multi-core and related recent progress in optical communication

    Science.gov (United States)

    Nakazawa, Masataka

    2014-11-01

    A compact 1.48 μm InGaAsP laser-diode (LD)-pumped erbium-doped optical fiber amplifier (EDFA) was invented in 1989 and it revolutionized optical communication in combination with a wavelength division multiplexing (WDM) technique. Recently, in addition to the existing single-core EDFA, a multi-core EDFA, which employs space division multiplexing (SDM), was developed to increase transmission capacity even further. The first half of this paper describes the evolution of the EDFA from a single-core to a multi-core device and the second half focuses on related topics in optical communication.

  5. A CORE approach to progress monitoring and feedback: Enhancing evidence and improving practice.

    Science.gov (United States)

    Barkham, Michael; Mellor-Clark, John; Stiles, William B

    2015-12-01

    This article describes the Clinical Outcomes in Routine Evaluation (CORE) System and reports on its scientific yield and practice impact. First, we describe the suite of CORE measures, including the centerpiece CORE-Outcome Measure (CORE-OM), its short forms, special purpose forms, translations, and psychometric properties, along with the pretreatment CORE Therapy Assessment Form and the CORE End of Therapy Form. Second, we provide an overview of the scientific yield arising from analyses of large CORE data sets collected in routine practice. Third, we describe the use of CORE measures for feedback in practice settings. Finally, we consider future directions for monitoring and feedback in research and practice.

  6. CORE

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Hundebøll, Martin

    2013-01-01

    different flows. Instead of maintaining these approaches separate, we propose a protocol (CORE) that brings together these coding mechanisms. Our protocol uses random linear network coding (RLNC) for intra- session coding but allows nodes in the network to setup inter- session coding regions where flows...... intersect. Routes for unicast sessions are agnostic to other sessions and setup beforehand, CORE will then discover and exploit intersecting routes. Our approach allows the inter-session regions to leverage RLNC to compensate for losses or failures in the overhearing or transmitting process. Thus, we...... increase the benefits of XORing by exploiting the underlying RLNC structure of individual flows. This goes beyond providing additional reliability to each individual session and beyond exploiting coding opportunistically. Our numerical results show that CORE outperforms both forwarding and COPE...

  7. CORE

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Hundebøll, Martin

    2013-01-01

    different flows. Instead of maintaining these approaches separate, we propose a protocol (CORE) that brings together these coding mechanisms. Our protocol uses random linear network coding (RLNC) for intra- session coding but allows nodes in the network to setup inter- session coding regions where flows...... intersect. Routes for unicast sessions are agnostic to other sessions and setup beforehand, CORE will then discover and exploit intersecting routes. Our approach allows the inter-session regions to leverage RLNC to compensate for losses or failures in the overhearing or transmitting process. Thus, we...... increase the benefits of XORing by exploiting the underlying RLNC structure of individual flows. This goes beyond providing additional reliability to each individual session and beyond exploiting coding opportunistically. Our numerical results show that CORE outperforms both forwarding and COPE...

  8. Research Progress of Nurses' Core Competence%护士核心能力的研究进展

    Institute of Scientific and Technical Information of China (English)

    姜黎黎; 李忆昔

    2016-01-01

    护士核心能力是护理人员从事护理工作的时具备的良好综合能力,即通科护士核心能力与专科护士核心能力。护理人员的核心能力能够为患者提供良好的护理服务,构建和谐的护患关系,提高患者治疗与护理的依从性,使患者的早日康复。通过对护士核心能力概念及意义进行介绍,综述国内外护士核心能力的研究现状及进展,总结我国护士核心能力的现状及面临的问题,以明确护士核心能力的意义。%The core competence is a good comprehensive ability of nursing staff in the nursing time, namely the core competence and the core competence of nurses nurses in general. The core ability of the nursing staff can provide good nursing service for patients, construct the harmonious nurse patient relationship, improve the patient's treatment and nursing compliance, so that the patient's early recovery. Based on the concept of core competence of nurses and signiifcance, research status and progress at home and abroad of nurses' core competence, summing up the status quo of Chinese nurses core competence and problems, in order to clear the signiifcance of the core competence of nurses.

  9. Recent progress on metal core@semiconductor shell nanocomposites as a promising type of photocatalyst

    Science.gov (United States)

    Zhang, Nan; Liu, Siqi; Xu, Yi-Jun

    2012-03-01

    The creation of core-shell nanocomposites (CSNs) has attracted considerable attention and developed into an increasingly important research area at the frontier of advanced materials chemistry. CSNs, which are nanoscaled assemblies with a chemical composition that is different on the surface compared to the core region, have found versatile applications in many fields, such as electrooptics, quantum dots, microscopy labels, drug delivery, chemical sensors, nanoreactors and catalysis. This review is primarily focused on the applications of metal core@semiconductor shell nanocomposites in heterogeneous photocatalysis, including photocatalytic nonselective processes for environmental remediation, selective organic transformations to fine chemicals and water splitting to clean hydrogen energy. It is hoped that this minireview can inspire multidisciplinary research interest in the precisely morphology-controlled synthesis of a variety of metal core@semiconductor shell nanoassemblies and their wide applications in the realm of heterogeneous photocatalysis.

  10. Work in Progress: Malleable Software Pipelines for Efficient Many-core System Utilization

    OpenAIRE

    Jahn, Janmartin; Kobbe, Sebastian; Pagani, Santiago; Chen, Jian-Jia; Henkel, Jörg

    2012-01-01

    International audience; This paper details our current research project on the efficient utilization of many-core systems by utilizing applications based on a novel kind of software pipelines. These pipelines form malleable applications that can change their degree of parallelism at runtime. This allows not only for a well-balanced load, but also for an efficient distribution of the cores to the individual, competing applications to maximize the overall system performance. We are convinced th...

  11. Progress in biological function of Api6/AIM/Spα in immune regulation and lipid metabolism%Api6/AIM/Spα调节免疫和脂质代谢的生物学功能研究

    Institute of Scientific and Technical Information of China (English)

    方严; 刘丹; 练雪梅

    2011-01-01

    Apoptosis inhibitor 6(Api6), also known as AIM and Spα, belongs to the scavenger receptor cysteine rich-superfamily (SRCR-SF). Api6/AIM/Spα, which is secreted exclusively by macrophages, inhibits apoptosis of CD4/CD8 double-positive (CD4+/CD8+) thymocytes, T cells, natural killer T(NKT) cells and macrophags. As a pattern recognition receptor, Api6/AIM/Spα is involved in the recognition of pathogen-associated molecular patterns(e.g. LPS and LTA), which suggests that it plays an important role in the regulation of the innate and adaptive immune systems. It has been confirmed recently that Api6/AIM/Spα increases early atherosclerotic lesion development by decreasing macrophage apoptosis. Api6/AIM/Spα also associates with cytosolic fatty acid synthase (FAS), decreases FAS activity, thereby inducing the lipolytic response within adipocytes and is physiologically relevanting to obesity progression. This paper introduced emphatically the progress in biological function of Api6/ AIM/Spα in immune regulation and lipid metabolism.%凋亡抑制因子6(apoptosis inhibitor 6,Api6),又称作AIM/Spa,是清道夫受体富含半胱氨酸残基超家族新成员.Api6/AIM/Spa由巨噬细胞特异性表达,具有抑制CD4+/CD8+双阳性胸腺细胞、T淋巴细胞、NKT淋巴细胞和巨噬细胞凋亡的作用.作为模式识别受体,Api6/AIM/Spα直接与病原体相关分子模式LPS/LTA结合,在机体固有免疫和适应性免疫中发挥重要的作用.近年研究发现,Api6/AIM/Spα可以通过抑制动脉粥样硬化斑块部位巨噬细胞凋亡加重动脉粥样硬化早期斑块的进展,也可以通过抑制脂肪酸合成酶(FAS)的生物学活性提高脂肪细胞的脂解作用,在肥胖的进展中发挥重要作用.重点综述了Api6/AIM/Spα调节免疫和脂质代谢等生物学功能的研究进展.

  12. Year 3 of Implementing the Common Core State Standards: An Overview of States' Progress and Challenges

    Science.gov (United States)

    Rentner, Diane Stark

    2013-01-01

    States are in a crucial phase of implementing the Common Core State Standards (CCSS), which outline the knowledge and skills that students in grades kindergarten through 12 are expected to learn in mathematics and English language arts (ELA) to be prepared for college and careers. As of July 2013, 45 states and the District of Columbia have…

  13. Fukushima Daiichi Unit 1 Uncertainty Analysis-Exploration of Core Melt Progression Uncertain Parameters-Volume II.

    Energy Technology Data Exchange (ETDEWEB)

    Denman, Matthew R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brooks, Dusty Marie [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    Sandia National Laboratories (SNL) has conducted an uncertainty analysi s (UA) on the Fukushima Daiichi unit (1F1) accident progression wit h the MELCOR code. Volume I of the 1F1 UA discusses the physical modeling details and time history results of the UA. Volume II of the 1F1 UA discusses the statistical viewpoint. The model used was developed for a previous accident reconstruction investigation jointly sponsored by the US Department of Energy (DOE) and Nuclear Regulatory Commission (NRC). The goal of this work was to perform a focused evaluation of uncertainty in core damage progression behavior and its effect on key figures - of - merit (e.g., hydrogen production, fraction of intact fuel, vessel lower head failure) and in doing so assess the applicability of traditional sensitivity analysis techniques .

  14. [Aiming for zero blindness].

    Science.gov (United States)

    Nakazawa, Toru

    2015-03-01

    -independent factors, as well as our investigation of ways to improve the clinical evaluation of the disease. Our research was prompted by the multifactorial nature of glaucoma. There is a high degree of variability in the pattern and speed of the progression of visual field defects in individual patients, presenting a major obstacle for successful clinical trials. To overcome this, we classified the eyes of glaucoma patients into 4 types, corresponding to the 4 patterns of glaucomatous optic nerve head morphology described: by Nicolela et al. and then tested the validity of this method by assessing the uniformity of clinical features in each group. We found that in normal tension glaucoma (NTG) eyes, each disc morphology group had a characteristic location in which the loss of circumpapillary retinal nerve fiber layer thickness (cpRNFLT; measured with optical coherence tomography: OCT) was most likely to occur. Furthermore, the incidence of reductions in visual acuity differed between the groups, as did the speed of visual field loss, the distribution of defective visual field test points, and the location of test points that were most susceptible to progressive damage, measured by Humphrey static perimetry. These results indicate that Nicolela's method of classifying eyes with glaucoma was able to overcome the difficulties caused by the diverse nature of the disease, at least to a certain extent. Building on these findings, we then set out to identify sectors of the visual field that correspond to the distribution of retinal nerve fibers, with the aim of detecting glaucoma progression with improved sensitivity. We first mapped the statistical correlation between visual field test points and cpRNFLT in each temporal clock-hour sector (from 6 to 12 o'clock), using OCT data from NTG patients. The resulting series of maps allowed us to identify areas containing visual field test points that were prone to be affected together as a group. We also used a similar method to identify visual

  15. Cretaceous shallow drilling, US Western Interior: Core research. Technical progress report

    Energy Technology Data Exchange (ETDEWEB)

    Arthur, M.A.

    1993-02-17

    This project is a continuing multidisciplinary study of middle to Upper Cretaceous marine carbonate and clastic rocks in the Utah-Colorado-Kansas corridor of the old Cretaceous seaway that extended from the Gulf Coast to the Arctic during maximum Cretaceous transgressions. It is collaborative between in the US Geological Survey (W.E. Dean, P.I.) and University researchers led by The Pennsylvania State University(M.A. Arthur, P.I.) and funded by DOE and the USGS, in part. Research focusses on the Greenhom, Niobrara and lower Pierre Shale units and their equivalents, combining biostratigraphic/paleoecologic studies, inorganic, organic and stable isotopic geochemical studies, mineralogical investigations and high-resolution geophysical logging. This research requires unweathered samples and continuous smooth ``exposures`` in the form of cores from at least 4 relatively shallow reference holes (i.e. < 1000m) in transect from east to west across the basin. The major initial effort was recovery in Year 1 of the project of continuous cores from each site in the transect. This drilling provided samples and logs of strata ranging from pelagic sequences that contain organic-carbon-rich marine source rocks to nearshore coal-bearing units. This transect also will provide information on the extent of thermal maturation and migration of hydrocarbons in organic-carbon-rich strata along a burial gradient.

  16. Precision disablement aiming system

    Energy Technology Data Exchange (ETDEWEB)

    Monda, Mark J.; Hobart, Clinton G.; Gladwell, Thomas Scott

    2016-02-16

    A disrupter to a target may be precisely aimed by positioning a radiation source to direct radiation towards the target, and a detector is positioned to detect radiation that passes through the target. An aiming device is positioned between the radiation source and the target, wherein a mechanical feature of the aiming device is superimposed on the target in a captured radiographic image. The location of the aiming device in the radiographic image is used to aim a disrupter towards the target.

  17. FY14 Q1 Progress Report for SECA Core Technology Program

    Energy Technology Data Exchange (ETDEWEB)

    Stevenson, Jeffry W.; Koeppel, Brian J.

    2014-01-31

    This quarterly progress report was prepared under field work proposal (FWP) 40552 and covers technical work performed during the period October 1 through December 31, 2013 (FY14 1st quarter). The report highlights and documents technical progress and milestone status in tasks related to advanced cell and stack component materials development and computational design and simulation. Technical highlights related to cell and stack materials development and characterization include: • Surface modified, Ce-modified MC spinel-coated AISI 441 exhibited improved spallation resistance (compared to coated mill reference 441) after 30,000 hours of oxidation at 800ºC in air. Similar beneficial results from surface modification were observed after 26,000 hours of oxidation at 850ºC. • MnCo spinel coatings prepared from metallic powder precursors exhibited low area-specific resistance after 12,000 hours of testing at 800°C. • Long-term validation tests (6,000 hours of operation followed by 10 deep thermal cycles) of surface-blasted, spinel-coated AISI 441 interconnects were completed using PNNL’s SECA CTP stack test fixture. Results of post-test results will be reported in the next quarterly progress report. • Long-term evaluation of compliant glass seals (SCN-1 glass with YSZ fibers) was in progress using PNNL’s SECA CTP stack test fixture. • Baseline testing of LSCF-based cells from Fuel Cell Materials was performed in PNNL’s SECA CTP stack test fixture. Overall performance was similar to that previously obtained with similar cells from H.C. Starck. • A study on pore coarsening of compliant glass seals with and without inert fillers (ZrO2 short fibers or ZrO2 crushed hollow balls) has reached 2,000 hours of testing; results to date indicate that the addition of the fillers was partially effective in hindering the pore coalescence process. • Cell tests attempting to correlate effects of fuel water content on anode performance with previously observed

  18. Recent progress on the spectroscopy of rare earth ions in core-shells, nanowires, nanotubes, and other novel nanostructures.

    Science.gov (United States)

    Chen, Xueyuan; Liu, Liqin; Liu, Guokui

    2008-03-01

    Research and development of nanoscale luminescent and laser materials are part of the rapidly advancing nanoscience and nanotechnology. Because of unique spectroscopic properties and luminescent dynamics of f-electron states, doping luminescent rare earth ions into nano-hosts has been demonstrated as an optimistic approach to developing highly efficient and stable nanophosphors for various applications. In this article, we review the most recent progress in spectroscopic measurements of rare earth ion-activated low-dimensional nanostructures including nanolayers, core-shells, nanowires, nanotubes, and nanodisks. Among a large volume of work reported in the literature on many members of the rare earth series including Ce3+, Pr3+, Nd3+, Eu3+, and Er3+, we focus on recent findings in the spectroscopic and luminescence properties of Eu3+ doped nanolayers, core-shells, and nanotubes, because Eu3+ ions have been extensively studied and widely used as an ideal probe for fundamental understanding of nano-phenomena. Specifically, the dependence of the optical properties of rare earth ions on nanostructures is discussed in detail.

  19. Precision laser aiming system

    Science.gov (United States)

    Ahrens, Brandon R.; Todd, Steven N.

    2009-04-28

    A precision laser aiming system comprises a disrupter tool, a reflector, and a laser fixture. The disrupter tool, the reflector and the laser fixture are configurable for iterative alignment and aiming toward an explosive device threat. The invention enables a disrupter to be quickly and accurately set up, aligned, and aimed in order to render safe or to disrupt a target from a standoff position.

  20. Progressive dry-core-wet-rim hydration trend in a nested-ring topology of protein binding interfaces

    Directory of Open Access Journals (Sweden)

    Li Zhenhua

    2012-03-01

    Full Text Available Abstract Background Water is an integral part of protein complexes. It shapes protein binding sites by filling cavities and it bridges local contacts by hydrogen bonds. However, water molecules are usually not included in protein interface models in the past, and few distribution profiles of water molecules in protein binding interfaces are known. Results In this work, we use a tripartite protein-water-protein interface model and a nested-ring atom re-organization method to detect hydration trends and patterns from an interface data set which involves immobilized interfacial water molecules. This data set consists of 206 obligate interfaces, 160 non-obligate interfaces, and 522 crystal packing contacts. The two types of biological interfaces are found to be drier than the crystal packing interfaces in our data, agreeable to a hydration pattern reported earlier although the previous definition of immobilized water is pure distance-based. The biological interfaces in our data set are also found to be subject to stronger water exclusion in their formation. To study the overall hydration trend in protein binding interfaces, atoms at the same burial level in each tripartite protein-water-protein interface are organized into a ring. The rings of an interface are then ordered with the core atoms placed at the middle of the structure to form a nested-ring topology. We find that water molecules on the rings of an interface are generally configured in a dry-core-wet-rim pattern with a progressive level-wise solvation towards to the rim of the interface. This solvation trend becomes even sharper when counterexamples are separated. Conclusions Immobilized water molecules are regularly organized in protein binding interfaces and they should be carefully considered in the studies of protein hydration mechanisms.

  1. AIMES Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Katz, Daniel S [Univ. of Illinois, Urbana-Champaign, IL (United States). National Center for Supercomputing Applications (NCSA); Jha, Shantenu [Rutgers Univ., New Brunswick, NJ (United States); Weissman, Jon [Univ. of Minnesota, Minneapolis, MN (United States); Turilli, Matteo [Rutgers Univ., New Brunswick, NJ (United States)

    2017-01-31

    This is the final technical report for the AIMES project. Many important advances in science and engineering are due to large-scale distributed computing. Notwithstanding this reliance, we are still learning how to design and deploy large-scale production Distributed Computing Infrastructures (DCI). This is evidenced by missing design principles for DCI, and an absence of generally acceptable and usable distributed computing abstractions. The AIMES project was conceived against this backdrop, following on the heels of a comprehensive survey of scientific distributed applications. AIMES laid the foundations to address the tripartite challenge of dynamic resource management, integrating information, and portable and interoperable distributed applications. Four abstractions were defined and implemented: skeleton, resource bundle, pilot, and execution strategy. The four abstractions were implemented into software modules and then aggregated into the AIMES middleware. This middleware successfully integrates information across the application layer (skeletons) and resource layer (Bundles), derives a suitable execution strategy for the given skeleton and enacts its execution by means of pilots on one or more resources, depending on the application requirements, and resource availabilities and capabilities.

  2. AIM Data Services

    Directory of Open Access Journals (Sweden)

    Michael Scholz

    2016-05-01

    Full Text Available AIM Data Services as a virtual facility provides virtual 3D reference tracks for simulation applications in the domain of automotive and railway systems. It offers tools for management and analysis of experiment data and a platform for survey and processing of vehicle data in the public transport domain. Collected spatial data is bundled in a database cluster and published through common web mapping interfaces.

  3. Aims of the Workshop

    CERN Document Server

    Dornan, P J

    2010-01-01

    There are challenges and opportunities for the European particle physics community to engage with innovative and exciting developments which could lead to precision measurements in the neutrino sector. These have the potential to yield significant advances in the understanding of CP violation, the flavour riddle and theories beyond the Standard Model. This workshop aims to start the process of a dialogue in Europe so that informed decisions on the appropriate directions to pursue can be made in a few years time.

  4. Aims and Scope

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    Chinese Nursing Research(CNR)is the official peer-reviewed research journal and an international platform of nursing academic exchange.This journal aims to promote excellence in nursing and health care through the dissemination of the latest,evidence-based,peer-reviewed research report,academic papers,review articles and clinical research,to reflect nursing academic trends,scientific research and

  5. Aiming for the ordinary

    DEFF Research Database (Denmark)

    Offersen, Sara Marie Hebsgaard

    and articulation of bodily sensations, and how decisions about healthcare seeking are established in this context. This dissertation aims to explore these matters from the perspective of the Danish middle class, mainly focusing on how sensations are ascribed meaning as symptoms and how they are evoked...... months of ethnographic fieldwork in a Danish middle class suburban neighbourhood, using participant observation, semi-structured interviews and health diaries. 18 key informants were followed with regular field visits, interviews and participation in everyday life activities as well as health...

  6. AIMES Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Jha, Shantenu [Rutgers Univ., New Brunswick, NJ (United States)

    2017-01-31

    Many important advances in science and engineering are due to large-scale distributed computing. Notwithstanding this reliance, we are still learning how to design and deploy large-scale production Distributed Computing Infrastructures (DCI). The AIMES project was conceived against this backdrop, following on the heels of a comprehensive survey of scienti c distributed applications [1]. The survey established, arguably for the rst time, the relationship between infrastructure and scienti c distributed applications. It examined well known contributors to the complexity associated with infrastructure, such as inconsistent internal and external interfaces, and demonstrated the correlation with application brittleness. It discussed how infrastructure complexity reinforces the challenges inherent in developing distributed applications.

  7. Further development of the environment related sustainability indicators and environment core indicator system for balancing the progress in the German sustainability strategy; Weiterentwicklung der umweltbezogenen Nachhaltigkeitsindikatoren und des Umwelt-Kernindikatorensystems zur Bilanzierung der Fortschritte in der deutschen Nachhaltigkeitsstrategie

    Energy Technology Data Exchange (ETDEWEB)

    Schoenthaler, Konstanze; Pieck, Sonja [Bosch und Partner GmbH, Muenchen (Germany)

    2013-05-15

    The Core Set of Environmental Indicators (KIS) presented by the Federal Environment Agency aims to inform policy makers and the interested public in an updated and concise form about environmental progress for a sustainable development in Germany. The Core Set completes the environmental indicators of the National Sustainability Indicator Set by several additional indicators describing environmental impacts and their causes. New legal regulations and political programs as well as innovations in the field of indicator development on the international and national level make a revision of the over ten-years-old Core Set of Environmental Indicators necessary. The project makes structural and content related proposals for such a revision. Following these proposals the Core Indicators shall cover a broader spectrum of environmental themes and problems in order to display cause-and-effect relationships in a more detailed way. The indicator set, which is proposed for the revised edition of KIS, comprises a total of 92 indicators, 49 out of them are directly focused on environmental issues. 43 indicators describe the activities of different economic sectors having relevant impacts on the environment. Furthermore the project offers a new thematic structure for the indicator set and a new classification of the indicators which shall facilitate the orientation and more effective search for themes and indicators within the system. A proposal for a metadata information system consisting of indicators and data factsheets was elaborated to better handle flow of information within the Federal Environment Agency.

  8. 硅基陶瓷型芯的研究进展%Research Progress of Silica-Base Ceramic Core

    Institute of Scientific and Technical Information of China (English)

    潘继勇; 刘孝福; 何立明; 郭新力; 刘东辉; 李长春

    2012-01-01

    硅基陶瓷型芯广泛用于1 550℃以下的Ni、Co基高温合金的精密铸造.综述了硅基陶瓷型芯的研究现状.重点介绍了影响硅基陶瓷型芯的主要因素:方石英含量、矿化剂、粉料粒度、烧成温度,并对脱芯工艺进行了阐述.%Silica-base ceramic core is widely used in the investment casting of Ni- and Co-base superalloys below 1 550 ℃. The research status of silica-base ceramic core was reviewed in this paper. Key factors influencing the properties of the ceramic core, such as cristobalite content, mineralizer, granularity and sintering temperature, were presented. Core removal process was also introduced.

  9. 核壳吸波材料的研究进展∗%Progress in core-shell absorbing materials

    Institute of Scientific and Technical Information of China (English)

    俞梁; 王建江; 许宝才; 李志广; 蔡旭东

    2015-01-01

    As a new core-shell composite absorbing material,as compared with a single type of absorbing mate-rial in the structure,properties and applications of absorbing has obvious advantages,the paper summarizes the basic types of core-shell absorbing materials,preparation methods and proposed a new method for self-reactive quenching + surface modification method.Pointed out that the core-shell absorbing material absorbing material is expected to meet the new"thin,light,wide,strong"requirements,and core-shell absorbing materials re-search proposed future prospects.%核壳吸波材料作为一种新型复合吸波材料,与单一类型的吸波材料相比在结构、吸波性能和应用上有着明显优势,本文总结了核壳吸波材料的基本类型、制备方法及提出了一种新的制备方法-自反应淬熄+表面改性法。指出核壳吸波材料有望满足新型吸波材料“薄、轻、宽、强”的要求,并对今后核壳吸波材料的研究提出展望。

  10. Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer

    DEFF Research Database (Denmark)

    Remmers, Neeley; Anderson, Judy M; Linde, Erin M;

    2013-01-01

    Mucin expression is a common feature of most adenocarcinomas and features prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and other adenocarcinomas. We investigated the expression of a number of mucin core proteins and associated O-linked glycans expressed...

  11. Functional Rehabilitation of Low Back Pain With Core Stabilizations Exercises: Suggestions for Exercises and Progressions in Athletes

    OpenAIRE

    Johnson, Joshua

    2012-01-01

    Introduction: Low back pain is very common in the adult population and accounts for more time lost form work than other diagnoses. It also affects athlete's at all different levels of competition and results in missed practice and game time. Diagnosing and treating a specific pathology is often difficult and because clinical evaluation and raidologic studies are often unable to find a root cause. A popular treatment approach with a high volume of anecdotal evidence is the use of core stabiliz...

  12. Influence of Modelling Options in RELAP5/SCDAPSIM and MAAP4 Computer Codes on Core Melt Progression and Reactor Pressure Vessel Integrity

    Directory of Open Access Journals (Sweden)

    Siniša Šadek

    2010-01-01

    Full Text Available RELAP5/SCDAPSIM and MAAP4 are two widely used severe accident computer codes for the integral analysis of the core and the reactor pressure vessel behaviour following the core degradation. The objective of the paper is the comparison of code results obtained by application of different modelling options and the evaluation of influence of thermal hydraulic behaviour of the plant on core damage progression. The analysed transient was postulated station blackout in NPP Krško with a leakage from reactor coolant pump seals. Two groups of calculations were performed where each group had a different break area and, thus, a different leakage rate. Analyses have shown that MAAP4 results were more sensitive to varying thermal hydraulic conditions in the primary system. User-defined parameters had to be carefully selected when the MAAP4 model was developed, in contrast to the RELAP5/SCDAPSIM model where those parameters did not have any significant impact on final results.

  13. Building core capacities at the designated points of entry according to the International Health Regulations 2005: a review of the progress and prospects in Taiwan

    Directory of Open Access Journals (Sweden)

    Hsiao-Hsuan Chiu

    2014-07-01

    Full Text Available Background: As designated points of entry (PoEs play a critical role in preventing the transmission of international public health risks, huge efforts have been invested in Taiwan to improve the core capacities specified in the International Health Regulations 2005 (IHR 2005. This article reviews how Taiwan strengthened the core capacities at the Taoyuan International Airport (TIA and the Port of Kaohsiung (PoK by applying a new, practicable model. Design: An IHR PoE program was initiated for implementing the IHR core capacities at designated PoEs. The main methods of this program were 1 identifying the designated PoEs according to the pre-determined criteria, 2 identifying the competent authority for each health measure, 3 building a close collaborative relationship between stakeholders from the central and PoE level, 4 designing three stages of systematic assessment using the assessment tool published by the World Health Organization (WHO, and 5 undertaking action plans targeting the gaps identified by the assessments. Results: Results of the self-assessment, preliminary external assessment, and follow-up external assessment revealed a continuous progressive trend at the TIA (86, 91, and 100%, respectively, and at the PoK (77, 97, and 99.9%, respectively. The results of the follow-up external assessment indicated that both these designated PoEs already conformed to the IHR requirements. These achievements were highly associated with strong collaboration, continuous empowerment, efficient resource integration, and sustained commitments. Conclusions: Considering that many countries had requested for an extension on the deadline to fulfill the IHR 2005 core capacity requirements, Taiwan's experiences can be a source of learning for countries striving to fully implement these requirements. Further, in order to broaden the scope of public health protection into promoting global security, Taiwan will keep its commitments on multisectoral cooperation

  14. Scoping assessments of ATF impact on late-stage accident progression including molten core-concrete interaction

    Science.gov (United States)

    Farmer, M. T.; Leibowitz, L.; Terrani, K. A.; Robb, K. R.

    2014-05-01

    Simple scoping models that can be used to evaluate ATF performance under severe accident conditions have been developed. The methodology provides a fundamental technical basis (a.k.a. metric) based on the thermodynamic boundary for evaluating performance relative to that of traditional Zr-based claddings. The initial focus in this study was on UO2 fuel with the advanced claddings 310 SS, D9, FeCrAl, and SiC. The evaluation considered only energy release with concurrent combustible gas production from fuel-cladding-coolant interactions and, separately, molten core-concrete interactions at high temperatures. Other important phenomenological effects that can influence the rate and extent of cladding decomposition (e.g., eutectic interactions, degradation of other core constituents) were not addressed. For the cladding types addressed, potential combustible gas production under both in-vessel and ex-vessel conditions was similar to that for Zr. However, exothermic energy release from cladding oxidation was substantially less for iron-based alloys (by at least a factor of 4), and modestly less (by ∼20%) for SiC. Data on SiC-clad UO2 fuel performance under severe accident conditions are sparse in the literature; thus, assumptions on the nature of the cladding decomposition process were made in order to perform this initial screening evaluation. Experimental data for this system under severe accident conditions is needed for a proper evaluation and comparison to iron-based claddings.

  15. Curriculum-based assessment of oral language and listening comprehension: a tool for intervention and progress monitoring in the Common Core State Standards.

    Science.gov (United States)

    Robinson, Wendy

    2012-05-01

    The Common Core State Standards and a Response to Intervention framework are movements sweeping the nation. Speech-language pathologists are uniquely positioned to play a pivotal role in supporting successful implementation of these movements. This article explores the assessment tools speech-language pathologists SLPs will need to identify and progress monitor critical language/literacy skills such as listening comprehension and oral narratives skills. Foundational research demonstrates that communication units, total words spoken, and major story components are measures that will discriminate between students with adequate language skills and language disorders and are curriculum-based, sensitive to change, and useful to determine the effectiveness of language/literacy interventions. Speech-language pathologist can broaden the impact of their knowledge and skills to improve outcomes for all students.

  16. Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression.

    Directory of Open Access Journals (Sweden)

    Bouchra Kitab

    Full Text Available BACKGROUND: Hepatitis B virus (HBV is one of the most common human pathogens that cause aggressive hepatitis and advanced liver disease (AdLD, including liver cirrhosis and Hepatocellular Carcinoma. The persistence of active HBV replication and liver damage after the loss of hepatitis B e antigen (HBeAg has been frequently associated with mutations in the pre-core (pre-C and core promoter (CP regions of HBV genome that abolish or reduce HBeAg expression. The purpose of this study was to assess the prevalence of pre-C and CP mutations and their impact on the subsequent course of liver disease in Morocco. METHODS/PRINCIPAL FINDINGS: A cohort of 186 patients with HBeAg-negative chronic HBV infection was studied (81 inactive carriers, 69 with active chronic hepatitis, 36 with AdLD. Pre-C and CP mutations were analyzed by PCR-direct sequencing method. The pre-C stop codon G1896A mutation was the most frequent (83.9% and was associated with a lower risk of AdLD development (OR, 0.4; 95% CI, 0.15-1.04; p = 0.04. HBV-DNA levels in patients with G1896A were not significantly different from the other patients carrying wild-type strains (p = 0.84. CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were associated with higher HBV-DNA level and increased liver disease severity. Multiple logistic regression analysis showed that older age (≥ 40 years, male sex, high viral load (>4.3 log(10 IU/mL and CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were independent risk factors for AdLD development. Combination of these mutations was significantly associated with AdLD (OR, 7.52; 95% CI, 4.8-8; p<0.0001. CONCLUSIONS: This study shows for the first time the association of HBV viral load and CP mutations with the severity of liver disease in Moroccan HBV chronic carriers. The examination of CP mutations alone or in combination could be helpful for prediction of the clinical outcome.

  17. Variability in the Precore and Core Promoter Regions of HBV Strains in Morocco: Characterization and Impact on Liver Disease Progression

    Science.gov (United States)

    Kitab, Bouchra; Essaid El Feydi, Abdellah; Afifi, Rajaa; Trepo, Christian; Benazzouz, Mustapha; Essamri, Wafaa; Zoulim, Fabien; Chemin, Isabelle; Alj, Hanane Salih; Ezzikouri, Sayeh; Benjelloun, Soumaya

    2012-01-01

    Background Hepatitis B virus (HBV) is one of the most common human pathogens that cause aggressive hepatitis and advanced liver disease (AdLD), including liver cirrhosis and Hepatocellular Carcinoma. The persistence of active HBV replication and liver damage after the loss of hepatitis B e antigen (HBeAg) has been frequently associated with mutations in the pre-core (pre-C) and core promoter (CP) regions of HBV genome that abolish or reduce HBeAg expression. The purpose of this study was to assess the prevalence of pre-C and CP mutations and their impact on the subsequent course of liver disease in Morocco. Methods/Principal Findings A cohort of 186 patients with HBeAg-negative chronic HBV infection was studied (81 inactive carriers, 69 with active chronic hepatitis, 36 with AdLD). Pre-C and CP mutations were analyzed by PCR-direct sequencing method. The pre-C stop codon G1896A mutation was the most frequent (83.9%) and was associated with a lower risk of AdLD development (OR, 0.4; 95% CI, 0.15–1.04; p = 0.04). HBV-DNA levels in patients with G1896A were not significantly different from the other patients carrying wild-type strains (p = 0.84). CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were associated with higher HBV-DNA level and increased liver disease severity. Multiple logistic regression analysis showed that older age (≥40 years), male sex, high viral load (>4.3 log10 IU/mL) and CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were independent risk factors for AdLD development. Combination of these mutations was significantly associated with AdLD (OR, 7.52; 95% CI, 4.8–8; pviral load and CP mutations with the severity of liver disease in Moroccan HBV chronic carriers. The examination of CP mutations alone or in combination could be helpful for prediction of the clinical outcome. PMID:22905181

  18. Progress Towards a Core Set of Outcome Measures in Small-vessel Vasculitis. Report from OMERACT 9

    Science.gov (United States)

    MERKEL, PETER A.; HERLYN, KAREN; MAHR, ALFRED D.; NEOGI, TUHINA; SEO, PHILIP; WALSH, MICHAEL; BOERS, MAARTEN; LUQMANI, RAASHID

    2011-01-01

    The past decade has seen a substantial increase in the number and quality of clinical trials of new therapies for vasculitis, including randomized, controlled, multicenter trials that have successfully incorporated measures of disease activity and toxicity. However, because current treatment regimens for severe disease effectively induce initial remission and reduce mortality, future trials will focus on any of several goals including: (a) treatment of mild—moderate disease; (b) prevention of chronic damage; (c) reduction in treatment toxicity; or (d) more subtle differences in remission induction or maintenance. Thus, new trials will require outcome measure instruments that are more precise and are better able to detect effective treatments for different disease states and measure chronic manifestations of disease. The OMERACT Vasculitis Working Group comprises international clinical investigators with expertise in vasculitis who, since 2002, have worked collaboratively to advance the refinement of outcome measures in vasculitis, create new measures to address domains of illness not covered by current research approaches, and harmonize outcome assessment in vasculitis. The focus of the OMERACT group to date has been on outcome measures in small-vessel vasculitis with an overall goal of creating a core set of outcome measures for vasculitis, each of which fulfills the OMERACT filter of truth, discrimination, feasibility, and identifying additional domains requiring further research. This process has been informed by several ongoing projects providing data on outcomes of disease activity, disease-related damage, multidimensional health-related quality of life, and patient-reported ratings of the burden of vasculitis. PMID:19820226

  19. Core outcome measures for interventions to prevent or slow the progress of dementia for people living with mild to moderate dementia: Systematic review and consensus recommendations

    Science.gov (United States)

    Groskreutz, Derek; Grinbergs-Saull, Anna; Howard, Rob; O’Brien, John T.; Mountain, Gail; Woods, Bob; Perneczky, Robert; McCleery, Jenny; Pickett, James; Challis, David; Charlesworth, Georgina; Featherstone, Katie; Jones, Roy; Schneider, Justine; Shepperd, Sasha; Thompson-Coon, Jo; Ballard, Clive; Burns, Alistair; Garrard, Peter; Kehoe, Patrick; Passmore, Peter; Robinson, Louise

    2017-01-01

    Background There are no disease-modifying treatments for dementia. There is also no consensus on disease modifying outcomes. We aimed to produce the first evidence-based consensus on core outcome measures for trials of disease modification in mild-to-moderate dementia. Methods and findings We defined disease-modification interventions as those aiming to change the underlying pathology. We systematically searched electronic databases and previous systematic reviews for published and ongoing trials of disease-modifying treatments in mild-to-moderate dementia. We included 149/22,918 of the references found; with 81 outcome measures from 125 trials. Trials involved participants with Alzheimer’s disease (AD) alone (n = 111), or AD and mild cognitive impairment (n = 8) and three vascular dementia. We divided outcomes by the domain measured (cognition, activities of daily living, biological markers, neuropsychiatric symptoms, quality of life, global). We calculated the number of trials and of participants using each outcome. We detailed psychometric properties of each outcome. We sought the views of people living with dementia and family carers in three cities through Alzheimer’s society focus groups. Attendees at a consensus conference (experts in dementia research, disease-modification and harmonisation measures) decided on the core set of outcomes using these results. Recommended core outcomes were cognition as the fundamental deficit in dementia and to indicate disease modification, serial structural MRIs. Cognition should be measured by Mini Mental State Examination or Alzheimer's Disease Assessment Scale-Cognitive Subscale. MRIs would be optional for patients. We also made recommendations for measuring important, but non-core domains which may not change despite disease modification. Limitations Most trials were about AD. Specific instruments may be superseded. We searched one database for psychometric properties. Interpretation This is the first review to

  20. The diverse aims of science.

    Science.gov (United States)

    Potochnik, Angela

    2015-10-01

    There is increasing attention to the centrality of idealization in science. One common view is that models and other idealized representations are important to science, but that they fall short in one or more ways. On this view, there must be an intermediary step between idealized representation and the traditional aims of science, including truth, explanation, and prediction. Here I develop an alternative interpretation of the relationship between idealized representation and the aims of science. I suggest that continuing, widespread idealization calls into question the idea that science aims for truth. If instead science aims to produce understanding, this would enable idealizations to directly contribute to science's epistemic success. I also use the fact of widespread idealization to motivate the idea that science's wide variety aims, epistemic and non-epistemic, are best served by different kinds of scientific products. Finally, I show how these diverse aims—most rather distant from truth—result in the expanded influence of social values on science. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. AIM: Attracting Women into Sciences.

    Science.gov (United States)

    Hartman, Icial S.

    1995-01-01

    Addresses how to attract more college women into the sciences. Attracting Women into Sciences (AIM) is a comprehensive approach that begins with advising, advertising, and ambiguity. The advising process includes dispelling stereotypes and reviewing the options open to a female basic science major. Interaction, involvement and instruction, finding…

  2. China Aims to Promote Import

    Institute of Scientific and Technical Information of China (English)

    Wang Ting

    2010-01-01

    @@ With the theme of"An Opening Market and Global Trade",aim at promoting communications and exchanges among governments,industries and business to achieve mutual benefit and a win-win situation,nearly 300 representatives from the relevant departments of the Chinese government,foreign embassies in China,industrial associations and major enterprises,as well as well-known Chinese and foreign experts and scholars were invited to take part in the forum and share their iews on Chinese market and foreign trade policies.

  3. The aims and accomplishments of comparative psychology.

    Science.gov (United States)

    Lickliter, Robert

    2004-01-01

    Greenberg, Partridge, Weiss, and Pisula propose a new perspective of comparative psychology, based in large part on an anagenetic and dynamic systems approach to the development and evolution of behavior. Their view appreciates the probabilistic nature of behavioral development and promotes the value of an integrative levels concept for generating testable hypothesis regarding the complex relationship between biology, context, and developmental history underlying behavioral and psychological functioning. However, the authors fail to represent the full scope of contemporary comparative psychology by overlooking several core aims of the field, including (a) the use of animal models to shed light on human behavior and development and (b) understanding the role of behavior as a leading edge in the evolutionary process.

  4. HTGR fuels and core development program. Quarterly progress report for the period ending November 30, 1976. [Graphite and fuel irradiations; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1976-12-27

    The work reported includes studies of reactions between core materials and coolant impurities, basic fission product transport mechanisms, core graphite development and testing, the development and testing of recyclable fuel systems, and physics and fuel management studies. Materials studies include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and the data are presented in tables, graphs, and photographs.

  5. HTGR Fuels and Core Development Program. Quarterly progress report for the period ending August 31, 1977. [Graphite and fuel irradiation; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    The work reported includes studies of reactions between core materials and coolant impurities, basic fission product transport mechanisms, core graphite development and testing, the development and testing of recyclable fuel systems, and physics and fuel management studies. Materials studies include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and data are presented.

  6. Building the Foundation: A Suggested Progression of Sub-Skills to Achieve the Reading Standards--Foundational Skills in the Common Core State Standards

    Science.gov (United States)

    Kosanovich, Marcia; Verhagen, Connie

    2012-01-01

    The Common Core State Standards (CCSS) initiative is a state-led effort that establishes a set of clear educational standards for English language arts and mathematics that states can voluntarily adopt. The standards have been informed by the best available evidence and the highest standards across the country and the world. They have been…

  7. InTASC Model Core Teaching Standards and Learning Progressions for Teachers 1.0: A Resource for Ongoing Teacher Development

    Science.gov (United States)

    Council of Chief State School Officers, 2013

    2013-01-01

    The Council of Chief State School Officers (CCSSO), through its Interstate Teacher Assessment and Support Consortium (InTASC), offers this set of combined resources that define and support ongoing teacher effectiveness to ensure students reach college and career ready standards. This document includes the "InTASC Model Core Teaching…

  8. HTGR fuels and core development program. Quarterly progress report for the period ending November 30, 1977. [Graphite and fuel irradiation; fission product release

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    The work reported here includes studies of basic fission product transport mechanisms, core graphite development and testing, and the development and testing of recyclable fuel systems. Materials studied include irradiation capsule tests of both fuel and graphite. Experimental procedures and results are discussed and data are presented.

  9. The research progress of cope-milled zirconia ceramic posts and cores%一体化氧化锆桩核的研究进展

    Institute of Scientific and Technical Information of China (English)

    邓璐; 曾利伟

    2012-01-01

    Cast metal post-core and fiber post and composite resin core are commonly used to restore residual crown and root, but the color problems of metal post-core and the poor fracture resistance of fiber post restrict their application. Zirconia post and core have high elastic modulus, less deformation at the stress state,and the stress is reliable to distribute in post and root, less post broken than fiber post and no influence on the porcelain crown restoration of the aesthetic effect and on MRI examination. It is more valued in clinic . The purpose of this paper is to give a literature review on the characteristics of zirconia post- core and the application scope, manufacture requirements and its bonding of clinical application.%采用金属桩核和纤维桩树脂核修复残根残冠已很普遍,但由于金属桩核的颜色问题和纤维桩的抗折性差,其应用受到限制.氧化锆桩核具有较高弹性模量,在应力状态下形变较小,利于应力在桩和牙根之间传递,较纤维桩少发生桩折断且不影响全瓷冠修复的美学效果和MRI等影像学结果等特性,使其在临床上受到重视.本文对一体化氧化锆桩核的特性、应用范围、加工制作要求和临床粘接应用作一概述.

  10. Proteomics Core

    Data.gov (United States)

    Federal Laboratory Consortium — Proteomics Core is the central resource for mass spectrometry based proteomics within the NHLBI. The Core staff help collaborators design proteomics experiments in a...

  11. Proteomics Core

    Data.gov (United States)

    Federal Laboratory Consortium — Proteomics Core is the central resource for mass spectrometry based proteomics within the NHLBI. The Core staff help collaborators design proteomics experiments in...

  12. NICHD Zebrafish Core

    Data.gov (United States)

    Federal Laboratory Consortium — The core[HTML_REMOVED]s goal is to help researchers of any expertise perform zebrafish experiments aimed at illuminating basic biology and human disease mechanisms,...

  13. Progress report on a new search for free e/3 quarks in the cores of 10(15) - 10(16) eV air showers

    Science.gov (United States)

    Hodson, A. L.; Bull, R. M.; Taylor, R. S.; Belford, C. H.

    1985-01-01

    The Leeds 3 sq m Wilson cloud chamber is being used in a new search for free e/3 quarks close to the axes of 10 to the 15th power - 10 to the 16th power eV air showers. A ratio trigger circuit is used to detect the incidence of air shower cores; the position of the shower center and the axis direction are determined from photographs of current-limited spark chambers. It is thus possible, for the first time, to know where we have looked for quarks in air showers and to select for scanning only those cloud chamber photographs where we have good evidence that the shower axis was close to the chamber. 250 g/sq cm of lead/concrete absorber above the cloud chamber serve to reduce particle densities and make a quark search possible very close to the shower axes. The current status of the search is given.

  14. AN ADAPTIVE ACO-DRIVEN SCHEME FOR LEARNING AIM ORIENTED PERSONALIZED E-LEARNING

    Directory of Open Access Journals (Sweden)

    Sushma Hans

    2014-10-01

    Full Text Available The e-learning paradigm is now a well-established vehicle of modern education. It caters to a wide spectrum of students with diverse backgrounds who enroll with their own learning aims. A core challenge under this scenario is to generate personalized learning paths so that each student can achieve her learning aim most effectively. Prior works used static attributes such as prior knowledge level, learning ability, browsing preferences, learning style etc. to generate personalized learning paths. In this paper, we take an entirely new route by taking into account the continuous improvement of a learner in the light of her own learning aim, to redefine her learning path at each level of the course. We introduce the concept of personalized examination system that systematically evaluates the dynamic learning ability of every student according to her pre-set goals. The proposed intelligent e-learning system uses Ant Colony Optimization to iteratively optimize the forward learning paths. Experimental results reveal that the system is able to tap a student’s improved learning ability to choose more difficult paths that contribute highly towards her own aims. We demonstrate that the overall learning success of weaker students doubles as compared to statically generated paths while there is considerable improvement of 50% in the learning success for average students as well. This clearly indicates that our approach gives realistic benefits to initially weak students who gradually evolve as the course progresses.

  15. What’s Wrong with Aim-Oriented Empiricism?

    Directory of Open Access Journals (Sweden)

    Nicholas Maxwell

    2015-10-01

    Full Text Available For four decades it has been argued that we need to adopt a new conception of science called aim-oriented empiricism. This has far-reaching implications and repercussions for science, the philosophy of science, academic inquiry in general, the conception of rationality, and how we go about attempting to make progress towards as good a world as possible. Despite these far-reaching repercussions, aim-oriented empiricism has so far received scant attention from philosophers of science. Here, sixteen objections to the validity of the argument for aim-oriented empiricism are subjected to critical scrutiny.

  16. What is Wrong With Aim-Oriented Empiricism?

    CERN Document Server

    Maxwell, Nicholas

    2015-01-01

    For four decades it has been argued that we need to adopt a new conception of science called aim-oriented empiricism. This has far-reaching implications and repercussions for science, the philosophy of science, academic inquiry in general, the conception of rationality, and how we go about attempting to make progress towards as good a world as possible. Despite these far-reaching repercussions, aim-oriented empiricism has so far received scant attention from philosophers of science. Here, sixteen objections to the validity of the argument for aim-oriented empiricism are subjected to critical scrutiny.

  17. Ice cores

    DEFF Research Database (Denmark)

    Svensson, Anders

    2014-01-01

    Ice cores from Antarctica, from Greenland, and from a number of smaller glaciers around the world yield a wealth of information on past climates and environments. Ice cores offer unique records on past temperatures, atmospheric composition (including greenhouse gases), volcanism, solar activity......, dustiness, and biomass burning, among others. In Antarctica, ice cores extend back more than 800,000 years before present (Jouzel et al. 2007), whereas. Greenland ice cores cover the last 130,000 years...

  18. Ice cores

    DEFF Research Database (Denmark)

    Svensson, Anders

    2014-01-01

    Ice cores from Antarctica, from Greenland, and from a number of smaller glaciers around the world yield a wealth of information on past climates and environments. Ice cores offer unique records on past temperatures, atmospheric composition (including greenhouse gases), volcanism, solar activity......, dustiness, and biomass burning, among others. In Antarctica, ice cores extend back more than 800,000 years before present (Jouzel et al. 2007), whereas. Greenland ice cores cover the last 130,000 years...

  19. Finding a Path to Entrustment in Undergraduate Medical Education: A Progress Report From the AAMC Core Entrustable Professional Activities for Entering Residency Entrustment Concept Group.

    Science.gov (United States)

    Brown, David R; Warren, Jamie B; Hyderi, Abbas; Drusin, Ronald E; Moeller, Jeremy; Rosenfeld, Melvin; Orlander, Philip R; Yingling, Sandra; Call, Stephanie; Terhune, Kyla; Bull, Janet; Englander, Robert; Wagner, Dianne P

    2017-06-01

    To better prepare graduating medical students to transition to the professional responsibilities of residency, 10 medical schools are participating in an Association of American Medical Colleges pilot to evaluate the feasibility of explicitly teaching and assessing 13 Core Entrustable Professional Activities for Entering Residency. The authors focused on operationalizing the concept of entrustment as part of this process. Starting in 2014, the Entrustment Concept Group, with representatives from each of the pilot schools, guided the development of the structures and processes necessary for formal entrustment decisions associated with students' increased responsibilities at the start of residency. Guiding principles developed by the group recommend that formal, summative entrustment decisions in undergraduate medical education be made by a trained group, be based on longitudinal performance assessments from multiple assessors, and incorporate day-to-day entrustment judgments by workplace supervisors. Key to entrustment decisions is evidence that students know their limits (discernment), can be relied on to follow through (conscientiousness), and are forthcoming despite potential personal costs (truthfulness), in addition to having the requisite knowledge and skills. The group constructed a developmental framework for discernment, conscientiousness, and truthfulness to pilot a model for transparent entrustment decision making. The pilot schools are studying a number of questions regarding the pathways to and decisions about entrustment. This work seeks to inform meaningful culture change in undergraduate medical education through a shared understanding of the assessment of trust and a shared trust in that assessment.

  20. INTEGRAL core programme

    Science.gov (United States)

    Gehrels, N.; Schoenfelder, V.; Ubertini, P.; Winkler, C.

    1997-01-01

    The International Gamma Ray Astrophysics Laboratory (INTEGRAL) mission is described with emphasis on the INTEGRAL core program. The progress made in the planning activities for the core program is reported on. The INTEGRAL mission has a nominal lifetime of two years with a five year extension option. The observing time will be divided between the core program (between 30 and 35 percent during the first two years) and general observations. The core program consists of three main elements: the deep survey of the Galactic plane in the central radian of the Galaxy; frequent scans of the Galactic plane in the search for transient sources, and pointed observations of several selected sources. The allocation of the observation time is detailed and the sensitivities of the observations are outlined.

  1. Responsiveness of the double limb lowering test and lower abdominal muscle progression to core stabilization exercise programs in healthy adults: a pilot study.

    Science.gov (United States)

    Haladay, Douglas E; Miller, Sayers J; Challis, John H; Denegar, Craig R

    2014-07-01

    Low back pain (LBP) is one of the most prevalent and expensive health care problems in the United States. Studies suggest that stabilization exercise may be effective in the management of people with LBP. To accurately assess the effect of stabilization programs on muscle performance, clinicians need an objective measure that is both valid and reliable. The purpose of this study was to determine whether the double limb lowering test (DLLT) and lower abdominal muscle progression (LAMP) can detect a change in abdominal muscle performance after stabilization exercises. Eleven healthy participants (4 men and 7 women) were randomly assigned to either a specific stabilization exercise (SSE) or general stabilization exercise (GSE) group and were evaluated by the DLLT and LAMP before, during, and at the end of 8 weeks of training. Subjects attended exercise sessions twice per week over 8 weeks. No significant difference in pretest performance existed between the 2 groups. No significant difference was detected with the DLLT for either the SSE or GSE over time or when groups were combined. The LAMP detected a significant difference for the combined groups and GSE but not SSE over time. These data indicate that the LAMP is sensitive to change after a spinal stabilization program, whereas the DLLT does not detect a change after these programs. Furthermore, the GSE was more effective in producing these changes. Additional testing of these assessments is necessary to further validate these tests and to identify specific populations for which these tests may be most appropriate.

  2. Take AIM and Keep Your Students Engaged

    Science.gov (United States)

    Nash, Catherine

    2014-01-01

    This paper outlines the benefits to distance education teachers of formatting a weekly online newsletter in accordance with motivational learning theory. It reflects on the delivery of weekly AIM newsletters to undergraduate economics students at the Open Polytechnic of New Zealand via Moodle. The acronym, AIM, stands for Academic content,…

  3. Is "Freedom" an Aim of Education?

    Science.gov (United States)

    Abinum, Joseph

    1979-01-01

    The purpose of this paper is to show that "freedom" properly understood cannot be an aim or an ideal of education, and that when educators talk of "freedom" as an aim or ideal of education, they usually have in mind the development of autonomy. (Author)

  4. Aims of education in South Africa

    Science.gov (United States)

    Morrow, Walter Eugene

    1990-06-01

    The first part of this paper gives a historical account of the aims of education under Apartheid, and discusses the ideological success of Apartheid education. The second part argues that a significant discussion — that is one which could have some purchase on schooling policy and educational practice — of aims of education in South Africa is not possible at present because the historical preconditions for such a discussion are not satisfied. It is argued that Apartheid has generated a political perspective which is unsympathetic to a discussion of aims of education; that the dominance of a social engineering model of schooling distorts a discussion of aims of education; and that a shared moral discourse, which is a necessary condition for a significant discussion of aims of education, does not yet exist in South Africa.

  5. Discrimination and the aim of proportional representation

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    2008-01-01

    Many organizations, companies, and so on are committed to certain representational aims as regards the composition of their workforce. One motivation for such aims is the assumption that numerical underrepresentation of groups manifests discrimination against them. In this article, I articulate...... representational aims in a way that best captures this rationale. My main claim is that the achievement of such representational aims is reducible to the elimination of the effects of wrongful discrimination on individuals and that this very important concern is, in principle, compatible with the representation...... of discrimination against numerically overrepresented groups, or overlook the innocently different ambitions of some numerically underrepresented groups. In relation to the latter point, I appeal to the fact that many luck egalitarians think justice should be ambition sensitive (but endowment insensitive). Also...

  6. On the Aims and Responsibilities of Science

    Directory of Open Access Journals (Sweden)

    Hugh Lacey

    2007-06-01

    Full Text Available I offer a view of the aims and responsibilities of science, and use it to analyze critically van Fraassen’s view that ‘objectifying inquiry’ is fundamental to the nature of science.

  7. Discrimination and the aim of proportional representation

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    2008-01-01

    Many organizations, companies, and so on are committed to certain representational aims as regards the composition of their workforce. One motivation for such aims is the assumption that numerical underrepresentation of groups manifests discrimination against them. In this article, I articulate...... representational aims in a way that best captures this rationale. My main claim is that the achievement of such representational aims is reducible to the elimination of the effects of wrongful discrimination on individuals and that this very important concern is, in principle, compatible with the representation...... of discrimination against numerically overrepresented groups, or overlook the innocently different ambitions of some numerically underrepresented groups. In relation to the latter point, I appeal to the fact that many luck egalitarians think justice should be ambition sensitive (but endowment insensitive). Also...

  8. Presentation of Database on Aims and Visions

    DEFF Research Database (Denmark)

    Lundgaard, Jacob

    2005-01-01

    This presentation presents a database on aims and visions regarding regional development and transport and infrastructure in the corridor from Oslo-Göteborg-Copenhagen-Berlin. The process, the developed methodology as well as the result of the database is presented.......This presentation presents a database on aims and visions regarding regional development and transport and infrastructure in the corridor from Oslo-Göteborg-Copenhagen-Berlin. The process, the developed methodology as well as the result of the database is presented....

  9. Is Fitts' law continuous in discrete aiming?

    Directory of Open Access Journals (Sweden)

    Rita Sleimen-Malkoun

    Full Text Available The lawful continuous linear relation between movement time and task difficulty (i.e., index of difficulty; ID in a goal-directed rapid aiming task (Fitts' law has been recently challenged in reciprocal performance. Specifically, a discontinuity was observed at critical ID and was attributed to a transition between two distinct dynamic regimes that occurs with increasing difficulty. In the present paper, we show that such a discontinuity is also present in discrete aiming when ID is manipulated via target width (experiment 1 but not via target distance (experiment 2. Fitts' law's discontinuity appears, therefore, to be a suitable indicator of the underlying functional adaptations of the neuro-muscular-skeletal system to task properties/requirements, independently of reciprocal or discrete nature of the task. These findings open new perspectives to the study of dynamic regimes involved in discrete aiming and sensori-motor mechanisms underlying the speed-accuracy trade-off.

  10. Herc SAR Task 106: AIMS Feature Development

    Science.gov (United States)

    2007-03-01

    prédécesseurs grâce à l’intégration de quatre capteurs dans un seul cardan. Pour offrir un rendement optimal, le système AIMS exige une interface et...qui simule l’utilisation et la commande de l’interface de capteur aéroporté a été élaborée par Recherche et Développement pour la défense Canada...système AIMS et de systèmes d’imagerie électro- optique semblables. Résulats Plusieurs importantes caractéristiques du système de simulation AIMS

  11. Transformer core

    NARCIS (Netherlands)

    Mehendale, A.; Hagedoorn, Wouter; Lötters, Joost Conrad

    2010-01-01

    A transformer core includes a stack of a plurality of planar core plates of a magnetically permeable material, which plates each consist of a first and a second sub-part that together enclose at least one opening. The sub-parts can be fitted together via contact faces that are located on either side

  12. Transformer core

    NARCIS (Netherlands)

    Mehendale, A.; Hagedoorn, Wouter; Lötters, Joost Conrad

    2008-01-01

    A transformer core includes a stack of a plurality of planar core plates of a magnetically permeable material, which plates each consist of a first and a second sub-part that together enclose at least one opening. The sub-parts can be fitted together via contact faces that are located on either side

  13. Aims and harvest of moral case deliberation.

    Science.gov (United States)

    Weidema, Froukje C; Molewijk, Bert A C; Kamsteeg, Frans; Widdershoven, Guy A M

    2013-09-01

    Deliberative ways of dealing with ethical issues in health care are expanding. Moral case deliberation is an example, providing group-wise, structured reflection on dilemmas from practice. Although moral case deliberation is well described in literature, aims and results of moral case deliberation sessions are unknown. This research shows (a) why managers introduce moral case deliberation and (b) what moral case deliberation participants experience as moral case deliberation results. A responsive evaluation was conducted, explicating moral case deliberation experiences by analysing aims (N = 78) and harvest (N = 255). A naturalistic data collection included interviews with managers and evaluation questionnaires of moral case deliberation participants (nurses). From the analysis, moral case deliberation appeals for cooperation, team bonding, critical attitude towards routines and nurses' empowerment. Differences are that managers aim to foster identity of the nursing profession, whereas nurses emphasize learning processes and understanding perspectives. We conclude that moral case deliberation influences team cooperation that cannot be controlled with traditional management tools, but requires time and dialogue. Exchanging aims and harvest between manager and team could result in co-creating (moral) practice in which improvements for daily cooperation result from bringing together perspectives of managers and team members.

  14. PRAGUE SEMINAR ON LANGUAGE TEACHING AIMS, 1967.

    Science.gov (United States)

    FRIED, VILEM

    AN INTERNATIONAL SEMINAR, WHOSE PURPOSE IT WAS TO DISCUSS THE STRUCTURAL DIFFERENCES IN LANGUAGE TEACHING AIMS, IS REPORTED ON IN THIS ARTICLE. THE THREE PAPERS PRESENTED BY IVAN POLDAUF, VALENTINA ZETLINA, AND JOHN B. CARROLL ARE REVIEWED FOR THEIR DISCUSSIONS ON LINGUISTICS, DIDACTICS, AND PSYCHOLOGY. THE DISCUSSION FOLLOWING THE PRESENTATION OF…

  15. Character as the Aim of Education

    Science.gov (United States)

    Shields, David Light

    2011-01-01

    The aim of education should be developing intellectual character, moral character, civic character, and performance character. That does not mean that schools should ignore teaching content, but that the dispositions and habits of mind that come from developing these four forms of character will remain with students throughout their lives.…

  16. Teacher Research and the Aims of Education

    Science.gov (United States)

    Leeman, Yvonne; Wardekker, Willem

    2014-01-01

    We report on the development of a course for experienced teachers in the Netherlands, intended to enhance their professionalism by engaging them in doing research based on reflection on the aims of their educational efforts. The course was accompanied by design-based research. The research question was whether and how the course stimulated…

  17. AIM: Ames Imaging Module Spacecraft Camera

    Science.gov (United States)

    Thompson, Sarah

    2015-01-01

    The AIM camera is a small, lightweight, low power, low cost imaging system developed at NASA Ames. Though it has imaging capabilities similar to those of $1M plus spacecraft cameras, it does so on a fraction of the mass, power and cost budget.

  18. [Continuing education aimed at occupational risk prevention].

    Science.gov (United States)

    De Vito, G; Tibiletti, M; Stella, A

    2007-01-01

    The implementation of European Commission directives has radically modified occupational risk management. In fact, widespread and continuous education addressed to exposed workers is seen by the legislator as one of the most effective means to avoid occupational diseases. The recent establishment of Continuing Medical Education (CME) has helped the system grant CME credits to participants in occupational courses organized by health-care providers. Moreover, the constant development of new health technologies coupled with the high productivity of the legislator confer a short lifetime on the acquired knowledge. Biological risks, biomechanical overload of the lumbar spine, and stress are among the classical risks requiring attention, discussion, and regular updating. Not only health-care workers but also safety technicians, occupational physicians, managers and union representatives should receive scheduled refresher training. Modern technologies such as distance learning, interactive simulation software, and online training tools are often the best teaching solutions. Occupational disease prevention should no longer be seen as a cost but as a cost savings indicator. Since it is closely related to quality promotion, it should play a primary role in the core business of health-care providers.

  19. Nanostructured core-shell electrode materials for electrochemical capacitors

    Science.gov (United States)

    Jiang, Long-bo; Yuan, Xing-zhong; Liang, Jie; Zhang, Jin; Wang, Hou; Zeng, Guang-ming

    2016-11-01

    Core-shell nanostructure represents a unique system for applications in electrochemical energy storage devices. Owing to the unique characteristics featuring high power delivery and long-term cycling stability, electrochemical capacitors (ECs) have emerged as one of the most attractive electrochemical storage systems since they can complement or even replace batteries in the energy storage field, especially when high power delivery or uptake is needed. This review aims to summarize recent progress on core-shell nanostructures for advanced supercapacitor applications in view of their hierarchical architecture which not only create the desired hierarchical porous channels, but also possess higher electrical conductivity and better structural mechanical stability. The core-shell nanostructures include carbon/carbon, carbon/metal oxide, carbon/conducting polymer, metal oxide/metal oxide, metal oxide/conducting polymer, conducting polymer/conducting polymer, and even more complex ternary core-shell nanoparticles. The preparation strategies, electrochemical performances, and structural stabilities of core-shell materials for ECs are summarized. The relationship between core-shell nanostructure and electrochemical performance is discussed in detail. In addition, the challenges and new trends in core-shell nanomaterials development have also been proposed.

  20. Advanced Industrial Materials (AIM) fellowship program

    Energy Technology Data Exchange (ETDEWEB)

    McCleary, D.D. [Oak Ridge Institute for Science and Education, TN (United States)

    1997-04-01

    The Advanced Industrial Materials (AIM) Program administers a Graduate Fellowship Program focused toward helping students who are currently under represented in the nation`s pool of scientists and engineers, enter and complete advanced degree programs. The objectives of the program are to: (1) establish and maintain cooperative linkages between DOE and professors at universities with graduate programs leading toward degrees or with degree options in Materials Science, Materials Engineering, Metallurgical Engineering, and Ceramic Engineering, the disciplines most closely related to the AIM Program at Oak Ridge National Laboratory (ORNL); (2) strengthen the capabilities and increase the level of participation of currently under represented groups in master`s degree programs, and (3) offer graduate students an opportunity for practical research experience related to their thesis topic through the three-month research assignment or practicum at ORNL. The program is administered by the Oak Ridge Institute for Science and Education (ORISE).

  1. Application of Core Dynamics Modeling to Core-Mantle Interactions

    Science.gov (United States)

    Kuang, Weijia

    2003-01-01

    Observations have demonstrated that length of day (LOD) variation on decadal time scales results from exchange of axial angular momentum between the solid mantle and the core. There are in general four core-mantle interaction mechanisms that couple the core and the mantle. Of which, three have been suggested likely the dominant coupling mechanism for the decadal core-mantle angular momentum exchange, namely, gravitational core-mantle coupling arising from density anomalies in the mantle and in the core (including the inner core), the electromagnetic coupling arising from Lorentz force in the electrically conducting lower mantle (e.g. D-layer), and the topographic coupling arising from non-hydrostatic pressure acting on the core-mantle boundary (CMB) topography. In the past decades, most effort has been on estimating the coupling torques from surface geomagnetic observations (kinematic approach), which has provided insights on the core dynamical processes. In the meantime, it also creates questions and concerns on approximations in the studies that may invalidate the corresponding conclusions. The most serious problem is perhaps the approximations that are inconsistent with dynamical processes in the core, such as inconsistencies between the core surface flow beneath the CMB and the CMB topography, and that between the D-layer electric conductivity and the approximations on toroidal field at the CMB. These inconsistencies can only be addressed with numerical core dynamics modeling. In the past few years, we applied our MoSST (Modular, Scalable, Self-consistent and Three-dimensional) core dynamics model to study core-mantle interactions together with geodynamo simulation, aiming at assessing the effect of the dynamical inconsistencies in the kinematic studies on core-mantle coupling torques. We focus on topographic and electromagnetic core-mantle couplings and find that, for the topographic coupling, the consistency between the core flow and the CMB topography is

  2. Tapping, grasping and aiming in ideomotor apraxia.

    Science.gov (United States)

    Ietswaart, Magdalena; Carey, David P; Della Sala, Sergio

    2006-01-01

    Very few studies have investigated sensorimotor control in apraxia using tasks that differ in movement complexity. Nevertheless, there is some evidence to suggest that spontaneous behaviour, although relatively preserved, can be rather clumsy or awkward, and that patients with ideomotor apraxia may have subtle kinematic abnormalities in movements made in the laboratory. It remains unclear whether patients with ideomotor apraxia perform normally on movements such as visually guided aiming, that may not depend on higher-order, more cognitive, processes and that are relatively unguided by overlearned contexts. In this study, three different sensorimotor tasks were given to the same sample of patients with quantified apraxic disturbance. Finger tapping, goal-directed grasping and aiming with and without visual feedback were examined in these patients. A clear dissociation was found between grossly impaired gesture imitation and intact motor programming of goal-directed movements with visual feedback. Apraxic patients were, however, impaired on aiming movements without visual feedback, suggesting that apraxia is associated with an increased reliance on integration of online visual information with feedforward/feedback somatosensory and motor signals. Furthermore, patients were impaired on single finger tapping which was a surprisingly good predictor of apraxia severity.

  3. Aeronomy of Ice in the Mesosphere (AIM)

    Science.gov (United States)

    2003-01-01

    The overall goal of the Aeronomy of Ice in the Mesosphere (AIM) experiment is to resolve why Polar Mesospheric Clouds form and why they vary. By measuring PMCs and the thermal, chemical and dynamical environment in which they form, we will quanti@ the connection between these clouds and the meteorology of the polar mesosphere. In the end, this will provide the basis for study of long-term variability in the mesospheric climate and its relationship to global change. The results of AIM will be a rigorous validation of predictive models that can reliably use past PMC changes and present trends as indicators of global change. The AIM goal will be achieved by measuring PMC extinction, brightness, spatial distribution, particle size distributions, gravity wave activity, dust influx to the atmosphere and precise, vertical profile measurements of temperature, H20, C&, 0 3 , C02, NO. and aerosols. These data can only be obtained by a complement of instruments on an orbiting spacecraft (S/C).

  4. Modeling Core Collapse Supernovae

    Science.gov (United States)

    Mezzacappa, Anthony

    2017-01-01

    Core collapse supernovae, or the death throes of massive stars, are general relativistic, neutrino-magneto-hydrodynamic events. The core collapse supernova mechanism is still not in hand, though key components have been illuminated, and the potential for multiple mechanisms for different progenitors exists. Core collapse supernovae are the single most important source of elements in the Universe, and serve other critical roles in galactic chemical and thermal evolution, the birth of neutron stars, pulsars, and stellar mass black holes, the production of a subclass of gamma-ray bursts, and as potential cosmic laboratories for fundamental nuclear and particle physics. Given this, the so called ``supernova problem'' is one of the most important unsolved problems in astrophysics. It has been fifty years since the first numerical simulations of core collapse supernovae were performed. Progress in the past decade, and especially within the past five years, has been exponential, yet much work remains. Spherically symmetric simulations over nearly four decades laid the foundation for this progress. Two-dimensional modeling that assumes axial symmetry is maturing. And three-dimensional modeling, while in its infancy, has begun in earnest. I will present some of the recent work from the ``Oak Ridge'' group, and will discuss this work in the context of the broader work by other researchers in the field. I will then point to future requirements and challenges. Connections with other experimental, observational, and theoretical efforts will be discussed, as well.

  5. TALEN gene editing takes aim on HIV.

    Science.gov (United States)

    Benjamin, Ronald; Berges, Bradford K; Solis-Leal, Antonio; Igbinedion, Omoyemwen; Strong, Christy L; Schiller, Martin R

    2016-09-01

    Transcription activator-like effector nucleases (TALENs) are one of several types of programmable, engineered nucleases that bind and cleave specific DNA sequences. Cellular machinery repairs the cleaved DNA by introducing indels. In this review, we emphasize the potential, explore progress, and identify challenges in using TALENs as a therapeutic tool to treat HIV infection. TALENs have less off-target editing and can be more effective at tolerating HIV escape mutations than CRISPR/Cas-9. Scientists have explored TALEN-mediated editing of host genes such as viral entry receptors (CCR5 and CXCR4) and a protein involved in proviral integration (LEDGF/p75). Viral targets include the proviral DNA, particularly focused on the long terminal repeats. Major challenges with translating gene therapy from bench to bedside are improving cleavage efficiency and delivery, while minimizing off-target editing, cytotoxicity, and immunogenicity. However, rapid improvements in TALEN technology are enhancing cleavage efficiency and specificity. Therapeutic testing in animal models of HIV infection will help determine whether TALENs are a viable HIV treatment therapy. TALENs or other engineered nucleases could shift the therapeutic paradigm from life-long antiretroviral therapy toward eradication of HIV infection.

  6. Ice Cores

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Records of past temperature, precipitation, atmospheric trace gases, and other aspects of climate and environment derived from ice cores drilled on glaciers and ice...

  7. Core BPEL

    DEFF Research Database (Denmark)

    Hallwyl, Tim; Højsgaard, Espen

    extensions. Combined with the fact that the language definition does not provide a formal semantics, it is an arduous task to work formally with the language (e.g. to give an implementation). In this paper we identify a core subset of the language, called Core BPEL, which has fewer and simpler constructs......, does not allow omissions, and does not contain ignorable elements. We do so by identifying syntactic sugar, including default values, and ignorable elements in WS-BPEL. The analysis results in a translation from the full language to the core subset. Thus, we reduce the effort needed for working...... formally with WS-BPEL, as one, without loss of generality, need only consider the much simpler Core BPEL. This report may also be viewed as an addendum to the WS-BPEL standard specification, which clarifies the WS-BPEL syntax and presents the essential elements of the language in a more concise way...

  8. Core BPEL

    DEFF Research Database (Denmark)

    Hallwyl, Tim; Højsgaard, Espen

    extensions. Combined with the fact that the language definition does not provide a formal semantics, it is an arduous task to work formally with the language (e.g. to give an implementation). In this paper we identify a core subset of the language, called Core BPEL, which has fewer and simpler constructs......, does not allow omissions, and does not contain ignorable elements. We do so by identifying syntactic sugar, including default values, and ignorable elements in WS-BPEL. The analysis results in a translation from the full language to the core subset. Thus, we reduce the effort needed for working...... formally with WS-BPEL, as one, without loss of generality, need only consider the much simpler Core BPEL. This report may also be viewed as an addendum to the WS-BPEL standard specification, which clarifies the WS-BPEL syntax and presents the essential elements of the language in a more concise way...

  9. Core benefits

    National Research Council Canada - National Science Library

    Keith, Brian W

    2010-01-01

    This SPEC Kit explores the core employment benefits of retirement, and life, health, and other insurance -benefits that are typically decided by the parent institution and often have significant governmental regulation...

  10. AIM cryocooler developments for HOT detectors

    Science.gov (United States)

    Rühlich, I.; Mai, M.; Withopf, A.; Rosenhagen, C.

    2014-06-01

    Significantly increased FPA temperatures for both Mid Wave and Long Wave IR detectors, i.e. HOT detectors, which have been developed in recent years are now leaving the development phase and are entering real application. HOT detectors allowing to push size weight and power (SWaP) of Integrated Detectors Cooler Assemblies (IDCA's) to a new level. Key component mainly driving achievable weight, volume and power consumption is the cryocooler. AIM cryocooler developments are focused on compact, lightweight linear cryocoolers driven by compact and high efficient digital cooler drive electronics (DCE) to also achieve highest MTTF targets. This technology is using moving magnet driving mechanisms and dual or single piston compressors. Whereas SX030 which was presented at SPIE in 2012 consuming less 3 WDC to operate a typical IDCA at 140K, next smaller cooler SX020 is designed to provide sufficient cooling power at detector temperature above 160K. The cooler weight of less than 200g and a total compressor length of 60mm makes it an ideal solution for all applications with limited weight and power budget, like in handheld applications. For operating a typical 640x512, 15μm MW IR detector the power consumption will be less than 1.5WDC. MTTF for the cooler will be in excess of 30,000h and thus achieving low maintenance cost also in 24/7 applications. The SX020 compressor is based on a single piston design with integrated passive balancer in a new design achieves very low exported vibration in the order of 100mN in the compressor axis. AIM is using a modular approach, allowing the chose between 5 different compressor types for one common Stirling expander. The 6mm expander with a total length of 74mm is now available in a new design that fits into standard dewar bores originally designed for rotary coolers. Also available is a 9mm coldfinger in both versions. In development is an ultra-short expander with around 35mm total length to achieve highest compactness. Technical

  11. Insect food aiming at Mars emigration

    Science.gov (United States)

    Katayama, Naomi; Yamashita, Masamichi; Hashimoto, Hirofumi; Nagasaka, Sanako; Kuwayama, Akemi; Sofue, Megumi

    2012-07-01

    We study insect food aiming at Mars emigration.In space agriculture, insect is the important creature which we cannot miss.It is necessary for the pollination of the plant, and it is rich to protein and lipid as food.I reported that silkworm is an insect necessary for astroponics in particular last time.We make clothes using silk thread, and the pupa becomes the food.In addition, the clothes can make food as protein when we need not to use it. The bee is a very important insect in the space agriculture,too.We examined nutrition of silkworm, bee, grasshopper, snail and the white ant which are necessary for Mars emigration.We will introduce of good balance space foods.We will report many meal menu for Mars emigration.

  12. Determination of aims military-technical policy of Ukraine

    Directory of Open Access Journals (Sweden)

    O. F. Salnikova

    2014-06-01

    Full Text Available In the article the aims of military-technical policy are considered. Determination of aims (tasks of military-technical policy, its maintenance, requirements to it and directions of its further development it must come true by the analysis of different factors of external and internal environment. Among such factors: geopolitical and military-political position of Ukraine and its military doctrine; realized and operating programs of development (reformation of the soldiery forming and them technical rigging; terms of future military operations and progress of their maintenance, forms, methods and characteristic signs of battle actions trend; substantive provisions of art of war; conceptions, theories and doctrines of battle application of the soldiery forming of the different states; resources dedicated by the state on development of military-technical sphere and others like that. The fundamental chart of sequence of forming of public military-technical policy is presented in the article.

  13. Research methodology the aims, practices and ethics of science

    CERN Document Server

    Pruzan, Peter

    2016-01-01

    This book is an in-depth guide to effective scientific research. Ranging from the philosophical to the practical, it explains at the outset what science can – and can’t – achieve, and discusses its relationship to mathematics and laws. The author then pays extensive attention to the scientific method, including experimental design, verification, uncertainty and statistics. A major aim of the book is to help young scientists reflect upon the deeper aims of their work and make the best use of their talents in contributing to progress. To this end, it also includes sections on planning research, on presenting one’s findings in writing, as well as on ethics and the responsibilities of scientists. .

  14. A Contrastive Study of Progressive Aspect in English and Chinese

    Institute of Scientific and Technical Information of China (English)

    田中锋

    2015-01-01

    Aspect, which is different from tense, deals with the internal structure of an action and allows people to describe or understand how an event unfolds over time. This paper examines the similarities and differences between English and Chinese progressive aspect in terms of form, meaning and use. The main findings are that in the first place the progressive aspect in both English and Chinese expresses the same core meaning, which is to describe the incomplete or ongoing state of an event or action. Secondly, the progressive aspect in English must be realized by grammatical device with inflectional changes, whereas in Chinese, it can be realized without verbal inflections (only with aspect markers). Thirdly, there exist differences between the English and Chinese progressive aspect in some specific usages. This contrastive study aims to deepen the understanding of the two languages, and provide practical and effective pedagogical suggestions for Chinese learners of English studying the progressive aspect.

  15. The Cosmic Dust Experiment of AIM

    Science.gov (United States)

    Poppe, A.; James, D.; Horanyi, M.

    2008-12-01

    The Cosmic Dust Experiment (CDE) onboard the Aeronomy of Ice in the Mesosphere (AIM) mission is a dust impact experiment designed to monitor the variability of the cosmic dust in ux. The instrument consists of fourteen permanently polarized thin plastic film sensors that generate an electrical signal when an impacting dust particle penetrates them. The total surface area is about 0.1 square meters and the detection threshold is about a micron in particle radius. The variability of these small grains is assumed to follow the variability of the dominant 100 micron radius particles, hence the measured flux can be used in correlation studies with various Noctilucent Cloud (NLC) activity indexes. CDE has been observing the cosmic dust influx since June 2007. In this talk, we present the first nine months of reduced data, focusing on the observed temporal and spatial variability of the dust influx. Data collected after February 2008 show increased levels of background noise and preliminary work on reducing this data will also be presented.

  16. Taking aim at novel vaccines market.

    Science.gov (United States)

    Awasthi, Sita

    2009-10-01

    The World Vaccine Congress Washington 2009 was held in Chantilly, VA USA April 2O -23rd. The Vaccine congress attracted over 400 participants from across the world, including leading vaccine manufacturers, biotechs, governmental agencies, NGOs, research and academic institutes, venture capital and legal firms, contract service and equipment manufacturers. The speakers covered a wide range of topics, including the role of government and regulatory agencies, funding availability, research and development, manufacturing, packaging and post vaccine evaluations. Past vaccine development efforts have historically focused on infectious diseases. With advancements in the field of immunology, molecular biology and vaccinology, the vaccine field has begun moving in new directions. "Taking aim at novel vaccines market" session chaired by Dr. Una Ryan, Chief Executive Officer of Waltham Technologies, was focused on traditional approaches to novel targets (nosocomial infections), novel approaches to traditional targets (flu and rabies), novel approaches to novel targets (Type 1 diabetes, multiple sclerosis and smoking) and vaccines for developing markets (TB, malaria, rabies). The importance of collaborations among academic institutions, industries, and philanthropic foundations for developing markets was also emphasized.

  17. AIM-9X Block II Sidewinder (AIM-9X Blk II)

    Science.gov (United States)

    2015-12-01

    Executive Summary The AIM-9X Block II missile completed Initial Operational Test and Evaluation ( IOT &E) in March 2015 and was found to be...carried. The AIM -9X Block II missile shall be compatible with representative threshold hose aircraft weapon and sensor load-outs with regard to

  18. TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy

    Directory of Open Access Journals (Sweden)

    Tao Liu

    2016-08-01

    Full Text Available The AIM2 inflammasome is a key cytosolic signaling complex that is activated by double-stranded DNA, leading to the maturation of proinflammatory cytokines such as interleukin-1β (IL-1β and IL-18. Dysregulated AIM2 inflammasome activity is associated with human inflammatory diseases and cancers, suggesting that its activity must be tightly regulated. However, the precise molecular mechanisms that control AIM2 levels and activity are still poorly understood. Here, we report tripartite motif 11 (TRIM11 as a key negative regulator of the AIM2 inflammasome. Upon DNA virus infection, TRIM11 binds to AIM2 via its PS domain and undergoes auto-polyubiquitination at K458 to promote an association between TRIM11 and the autophagic cargo receptor p62 to mediate AIM2 degradation via selective autophagy. These findings identify a role for TRIMs in AIM2 inflammasome activation where TRIM11 acts as a secondary receptor to deliver AIM2 to the autophagosomes for degradation in a p62-dependent manner.

  19. Core Java

    CERN Document Server

    Horstmann, Cay S

    2013-01-01

    Fully updated to reflect Java SE 7 language changes, Core Java™, Volume I—Fundamentals, Ninth Edition, is the definitive guide to the Java platform. Designed for serious programmers, this reliable, unbiased, no-nonsense tutorial illuminates key Java language and library features with thoroughly tested code examples. As in previous editions, all code is easy to understand, reflects modern best practices, and is specifically designed to help jumpstart your projects. Volume I quickly brings you up-to-speed on Java SE 7 core language enhancements, including the diamond operator, improved resource handling, and catching of multiple exceptions. All of the code examples have been updated to reflect these enhancements, and complete descriptions of new SE 7 features are integrated with insightful explanations of fundamental Java concepts.

  20. Physicians’ progress notes

    DEFF Research Database (Denmark)

    Bansler, Jørgen P.; Havn, Erling C.; Mønsted, Troels

    2013-01-01

    care, they have not dealt specifically with the role, structure, and content of the progress notes. As a consequence, CSCW research has not yet taken fully into account the fact that progress notes are coordinative artifacts of a rather special kind, an open-ended chain of prose texts, written...... sequentially by cooperating physicians for their own use as well as for that of their colleagues. We argue that progress notes are the core of the medical record, in that they marshal and summarize the overwhelming amount of data that is available in the modern hospital environment, and that their narrative...

  1. Popper, Kuhn, Lakatos and Aim-Oriented Empiricism

    CERN Document Server

    Maxwell, Nicholas

    2012-01-01

    In this paper I argue that aim-oriented empiricism (AOE), a conception of natural science that I have defended at some length elsewhere, is a kind of synthesis of the views of Popper, Kuhn and Lakatos, but is also an improvement over the views of all three. Whereas Popper's falsificationism protects metaphysical assumptions implicitly made by science from criticism, AOE exposes all such assumptions to sustained criticism, and furthermore focuses criticism on those assumptions most likely to need revision if science is to make progress. Even though AOE is, in this way, more Popperian than Popper, it is also, in some respects, more like the views of Kuhn and Lakatos than falsificationism is. AOE is able, however, to solve problems which Kuhn's and Lakatos's views cannot solve.

  2. Synthesis, Crystal Structure, Thermal Decomposition and Sensitivity Properties of (AIM)(HTNR) and (AIM)(PA)

    Institute of Scientific and Technical Information of China (English)

    TANG Zhan; YANG Li; QIAO Xiao-jing; WU Bi-dong; ZHANG Tong-lai; ZHOU Zun-ning; YU Kai-bei

    2012-01-01

    Two new energetic compounds (AIM)(HTNR) and (AIM)(PA)(AIM=2-azidoimidazole,TNR=2,4,6-trinitroresorcinol,PA=picric acid) have been prepared by AIM(2-azidoimidazolium) and TNR(2,4,6-trinitroresorcinol) or PA(picric acid) and characterized by elemental analysis and FTIR spectrum.Their crystal structures were determined by X-ray single-crystal diffraction analysis.The obtained results show that (AIM)(HTNR) crystal belongs to monoclinic,P2(1)/c space group,a=1.1306(2) nm,b=0.70305(14) nm,c=1.7398(4) nm,β=106.91°,V=1.3231(5) nm3,Dc=1.778 g/cm3,Z=4,R1=0.0524,wR2[I>2σ(I)]=0.1067 and S=1.092 and (AIM)(PA) crystal belongs to monoclinic P21/c space group,a=0.80303(16) nm,b=0.81395(16) nm,c=2.0471(4) nm,β=93.93(3)°,V=1.3349(5) nm3,Dc=1.683g/cm3,Z=4,R1=0.0784,wR2[I>2σ(I)]=0.1814 and S=1.098.Both the compounds have electrostatic attraction and hydrogen bonds,which contribute to making the constructions more stable.The decomposition of the two compounds was studied via differential scanning calorimetry(DSC) and thermogravimetry-derivative thermogravimetry(TG-DTG)techniques at a heating rate of 10 ℃/min,and the results show that both the compounds underwent one intensive exothermic decomposition stage.Sensitivity tests reveal that the title compounds were insensitive to friction and impact and sensitive to flame and could be applied in potential pyrotechnics.

  3. IR technology for enhanced force protection by AIM

    Science.gov (United States)

    Breiter, R.; Ihle, T.; Rode, W.; Wendler, J.; Rühlich, I.; Haiml, M.; Ziegler, J.

    2008-04-01

    In all recent missions our forces are faced with various types of asymmetric threads like snipers, IEDs, RPGs or MANPADS. 2 nd and 3 rd Gen IR technology is a backbone of modern force protection by providing situational awareness and accurate target engagement at day/night. 3 rd Gen sensors are developed for thread warning capabilities by use of spectral or spatial information. The progress on a dual-color IR module is discussed in a separate paper [1]. A 1024x256 SWIR array with flexure bearing compressor and pulse tube cold finger provides > 50,000h lifetime for space or airborne hyperspectral imaging in pushbroom geometry with 256 spectral channels for improved change detection and remote sensing of IEDs or chemical agents. Similar concepts are pursued in the LWIR with either spectroscopic imaging or a system of LWIR FPA combined with a cooled tunable Laser to do spectroscopy with stimulated absorption of specific wavelengths. AIM introduced the RangIR sight to match the requirements of sniper teams, AGLs and weapon stations, extending the outstanding optronic performance of the fielded HuntIR with position data of a target by a laser range finder (LRF), a 3 axis digital magnetic compass (DMC) and a ballistic computer for accurate engagement of remote targets. A version with flexure bearing cooler with >30,000h life time is being developed for continuous operation in e.g. gunfire detection systems. This paper gives an overview of AIM's technologies for enhanced force protection.

  4. Pre-supernova neutrino emissions from ONe cores in the progenitors of core-collapse supernovae: are they distinguishable from those of Fe cores?

    CERN Document Server

    Kato, Chinami; Yamada, Shoichi; Takahashi, Koh; Umeda, Hideyuki; Yoshida, Takashi; Ishidoshiro, Koji

    2015-01-01

    Aiming to distinguish two types of progenitors of core collapse supernovae, i.e., one with a core composed mainly of oxygen and neon (abbreviated as ONe core) and the other with an iron core (or Fe core), we calculated the luminosities and spectra of neutrinos emitted from these cores prior to gravitational collapse, taking neutrino oscillation into account. We found that the total energies emitted as $\\bar{\

  5. Central core disease

    Directory of Open Access Journals (Sweden)

    Jungbluth Heinz

    2007-05-01

    Full Text Available Abstract Central core disease (CCD is an inherited neuromuscular disorder characterised by central cores on muscle biopsy and clinical features of a congenital myopathy. Prevalence is unknown but the condition is probably more common than other congenital myopathies. CCD typically presents in infancy with hypotonia and motor developmental delay and is characterized by predominantly proximal weakness pronounced in the hip girdle; orthopaedic complications are common and malignant hyperthermia susceptibility (MHS is a frequent complication. CCD and MHS are allelic conditions both due to (predominantly dominant mutations in the skeletal muscle ryanodine receptor (RYR1 gene, encoding the principal skeletal muscle sarcoplasmic reticulum calcium release channel (RyR1. Altered excitability and/or changes in calcium homeostasis within muscle cells due to mutation-induced conformational changes of the RyR protein are considered the main pathogenetic mechanism(s. The diagnosis of CCD is based on the presence of suggestive clinical features and central cores on muscle biopsy; muscle MRI may show a characteristic pattern of selective muscle involvement and aid the diagnosis in cases with equivocal histopathological findings. Mutational analysis of the RYR1 gene may provide genetic confirmation of the diagnosis. Management is mainly supportive and has to anticipate susceptibility to potentially life-threatening reactions to general anaesthesia. Further evaluation of the underlying molecular mechanisms may provide the basis for future rational pharmacological treatment. In the majority of patients, weakness is static or only slowly progressive, with a favourable long-term outcome.

  6. Total syntheses of the elusive welwitindolinones with bicyclo[4.3.1] cores.

    Science.gov (United States)

    Huters, Alexander D; Styduhar, Evan D; Garg, Neil K

    2012-04-16

    The welwitindolinones with bicyclo[4.3.1] cores are a class of natural products that have attracted tremendous interest from the synthetic community because of their fascinating structures and promising biological profiles. More than 15 research groups worldwide have reported progress toward these elusive natural products. This Minireview describes contemporary studies aimed at the total synthesis of these challenging targets, in addition to the two recently completed syntheses of welwitindolinones with bicyclo[4.3.1] cores reported by Rawal and Garg in 2011. Both of the completed efforts rely on C4-C11 bond constructions to access the congested bicyclic framework of these elusive natural products.

  7. Exploration of new perspectives and limitations in Agrobacterium mediated gene transfer technology. Progress report, [June 1, 1992-- May 31, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Marton, L.

    1994-12-31

    This report describes progress aimed at constructing gene-transfer technology for Nicotiana plumbaginifolia. Most actual effort as described herein has so far been directed at exploring new perspectives and limitations in Agrobacterium mediated gene transfer. Accomplishments are described using a core homologous gene targeting vector.

  8. Recent progress in the study of core-shell-structured materials with metal organic frameworks (MOFs) as shell%金属有机骨架(MOFs)为壳的核壳结构材料研究进展

    Institute of Scientific and Technical Information of China (English)

    农洁静; 赵文波; 覃显业; 刘彪; 张政

    2015-01-01

    MOFs核壳结构材料是近十几年来化工材料领域的研究热点,其中MOFs可作核,亦可作壳。本文从不同的核出发综述了以 MOFs 为壳的核壳结构材料的合成方法,如外延生长法、后合成修饰法等;概述了其展现出优于核层与壳层的特性(如选择性分离、催化性、磁性等)及以 MOFs 为壳的核壳结构材料在气体吸附、催化剂、磁性分离等应用上的研究,这给MOFs复合材料的产业化带来很大的潜力;而内核主要包括单质金属及非金属类内核、氧化物类内核、MOFs类内核;最后对MOFs为壳的核壳结构复合材料合成方法的改进和拓展、结构均一稳定、多功能化的发展作了展望。%Core-shell-structure MOFs materials became a hot spot in the field of chemical and materials over the last decade,and MOFs can act as core or shell. This paper mainly reviews the synthesis methods of core-shell-structure material with MOFs as shell according to different nuclear types,such as epitaxial growth method,and post-synthetic modifications;and summarizes the performances which are better than single core or shell,such as separation selectivity,catalysis,magnetic performance, and the development of the core-shell-structure materials with MOFs as shell in gas adsorption, catalysts,magnetic separation,which bring a large potential for MOFs composite industrialization. The cores include metallic and non-metallic element core , oxides core , and MOFs core. And the core-shell-structure composites with MOFs as shell are prospected for the improvement and development of synthesis methods in order to obtain uniform and stable structure and multi-function.

  9. Discussion on the Progressive Teaching Pattern with the Core of Skills Experience%以技能体验为核心的递进式教学模式探讨

    Institute of Scientific and Technical Information of China (English)

    王洪彬

    2015-01-01

    Training on college students’ skill is one of the important issues in the teaching reform of higher education in recent years,which teaching pattern we are supposed to choice is the core of the research. Combined with the skills of the formation of the common law, progressive teaching pattern can be divided into three stages,through the teaching task of every stage,and then they are divided into seven parts, they are:knowledge learning, concept conclusion, fragments of imitation, integration and the practice,multiple stereo type training,pre job and on-the-job training. The first phase of the main task is to make the students to have a clear image or recognition in their mind or operation;the second stage is to highlight the skills of each fragment,and then combined with the story, imitation and instruments and other methods to complete the integration of skills. The third stage is to achieve the comprehensive ability of the training,to achieve the pur-suit of practical skills. Studies suggest that this teaching model can provide a skill operation of the simulation space or skills training experience, which can make the students integrate into the workplace faster and better.%大学生技能培养是近年来高校教学改革探讨的重要议题之一,采用何种教学模式实现培养目标则是研究核心。本文结合技能形成的普遍规律,将递进式教学模式分为三个阶段,通过每一个阶段的教学任务,再划分成知识学习、概念建立、片段模仿、整合练习、多元立体式训练、岗前和顶岗实训七个模块。第一阶段主要任务是使学生在头脑中或操作上,对技能有一个清晰的映像或认知;第二阶段要凸显每个片段技能特点,然后再结合讲述、模仿和器械等方法完成技能的整合。第三阶段是通过特色的教学设计等,追求技能的实用化,实现综合能力的培养。研究认为,这种教学模式可以提供一个技能操作

  10. Physicians’ Progress Notes

    DEFF Research Database (Denmark)

    Bansler, Jørgen; Havn, Erling C.; Mønsted, Troels

    2013-01-01

    This paper examines physicians’ progress notes, an artifact that, in spite of its obvious importance in the coordination of cooperative work in clinical settings, has not been subjected to systematic study under CSCW auspices. While several studies have addressed the role of the medical record...... in patient care, they have not dealt specifically with the role, structure, and content of the progress notes. As a consequence, CSCW research has not yet taken fully into account the fact that progress notes are coordinative artifacts of a rather special kind, an open-ended chain of prose texts, written...... sequentially by cooperating physicians for their own use as well as for that of their colleagues. We argue that progress notes are the core of the medical record, in that they marshal and summarize the overwhelming amount of data that is available in the modern hospital environment, and that their narrative...

  11. The fairest core in cooperative games with transferable utilities

    OpenAIRE

    2014-01-01

    The core and the Shapley value are important solution concepts in cooperative game theory. While the core is designed for the stability of the game, the Shapley value aims for fairness among the players. However, the Shapley value might not lie within the core and a core solution might not be ‘fair’. We introduce a new solution concept called the ‘fairest core’, one that aims for both stability and fairness. We show attractive properties of the fairest core.

  12. Gas-Cooled Reactor Programs annual progress report for period ending December 31, 1973. [HTGR fuel reprocessing, fuel fabrication, fuel irradiation, core materials, and fission product distribution; GCFR fuel irradiation and steam generator modeling

    Energy Technology Data Exchange (ETDEWEB)

    Kasten, P.R.; Coobs, J.H.; Lotts, A.L.

    1976-04-01

    Progress is summarized in studies relating to HTGR fuel reprocessing, refabrication, and recycle; HTGR fuel materials development and performance testing; HTGR PCRV development; HTGR materials investigations; HTGR fuel chemistry; HTGR safety studies; and GCFR irradiation experiments and steam generator modeling.

  13. Dual-core antiresonant hollow core fibers.

    Science.gov (United States)

    Liu, Xuesong; Fan, Zhongwei; Shi, Zhaohui; Ma, Yunfeng; Yu, Jin; Zhang, Jing

    2016-07-25

    In this work, dual-core antiresonant hollow core fibers (AR-HCFs) are numerically demonstrated, based on our knowledge, for the first time. Two fiber structures are proposed. One is a composite of two single-core nested nodeless AR-HCFs, exhibiting low confinement loss and a circular mode profile in each core. The other has a relatively simple structure, with a whole elliptical outer jacket, presenting a uniform and wide transmission band. The modal couplings of the dual-core AR-HCFs rely on a unique mechanism that transfers power through the air. The core separation and the gap between the two cores influence the modal coupling strength. With proper designs, both of the dual-core fibers can have low phase birefringence and short modal coupling lengths of several centimeters.

  14. Experimental course of bioethics upon the bioethics core curriculum of UNESCO: methodoloy and result of investigation.

    Science.gov (United States)

    Davtyan, S

    2012-12-01

    In October 2005 the General Conference of UNESCO adopted the Universal Declaration on Bioethics and Human Rights. The aim of this Declaration was to assist in the realization ofprinciples and support the thorough understanding of the consequences of the ethics of scientific and technical progress, especially for youth. In 2008, the Division of Ethics of Science and Technology Sector for Social and Human Sciences of UNESCO worked out an Educational Program (Bioethics Core Curriculum). On November 23, 2010 a Memorandum was signed between UNESCO and the Yerevan State Medical University after M. Heratsi. The Memorandum was aimed to test the Bioethics Core Curriculum of UNESCO. In this article we will analyze the aims and goals of studying the course, as well as disputable shortcomings of the Program, make recommendations for the improvement of the course of bioethics, and highlight the positive aspects of this Educational Program.

  15. Animal MRI Core

    Data.gov (United States)

    Federal Laboratory Consortium — The Animal Magnetic Resonance Imaging (MRI) Core develops and optimizes MRI methods for cardiovascular imaging of mice and rats. The Core provides imaging expertise,...

  16. Ultimate Educational Aims, Overridingness, and Personal Well-Being

    Science.gov (United States)

    Haji, Ishtiyaque; Cuypers, Stefaan E.

    2011-01-01

    Discussion regarding education's aims, especially its ultimate aims, is a key topic in the philosophy of education. These aims or values play a pivotal role in regulating and structuring moral and other types of normative education. We outline two plausible strategies to identify and justify education's ultimate aims. The first associates these…

  17. Rapidly progressive Alzheimer disease.

    Science.gov (United States)

    Schmidt, Christian; Wolff, Martin; Weitz, Michael; Bartlau, Thomas; Korth, Carsten; Zerr, Inga

    2011-09-01

    Different rates of progression have been observed among patients with Alzheimer disease. Risk factors that accelerate deterioration have been identified and some are being discussed, such as genetics, comorbidity, and the early appearance of Alzheimer disease motor signs. Progressive forms of Alzheimer disease have been reported with rapid cognitive decline and disease duration of only a few years. This short review aims to provide an overview of the current knowledge of rapidly progressive Alzheimer disease. Furthermore, we suggest that rapid, in this context, should be defined as a Mini-Mental State Examination score decrease of 6 points per year.

  18. Geochemical Mapping——Evolution of Its Aims, Ideas and Technology

    Institute of Scientific and Technical Information of China (English)

    XIE Xuejing

    2008-01-01

    The development of geochemical mapping progressed from local geochemical prospecting through regional geochemical exploration and regional geochemical mapping to national and global geochemical mapping. This paper discusses the evolution of aims, ideas and methodology of geochemical mapping in Western countries, Russia and China. The sophistication of geochemical mapping methodology will make great contributions to solving resources and environmental problems in the 21st century.

  19. Hepatitis C virus core proteins derived from different quasispecies of genotype 1b inhibit the growth of Chang liver cells

    Institute of Scientific and Technical Information of China (English)

    Xue-Bing Yan; Lei Mei; Xia Feng; Mei-Rong Wan; Zhi Chen; Nicole Pavia; Christian Brechot

    2008-01-01

    AIM: To investigate the influence of different quasispecies of hepatitis C virus (HCV) genotype 1b core protein on growth of Chang liver cells.METHODS: Three eukaryotic expression plasmids (pEGFP-N1/core) that contained different quasispecies truncated core proteins of HCV genotype 1b were constructed. These were derived from tumor (T) and nontumor (NT) tissues of a patient infected with HCV and C191 (HCV-J6). The core protein expression plasmids were transiently transfected into Chang liver cells. At different times, the cell cycle and apoptosis was assayed by flow cytometry, and cell proliferation was assayed by methyl thiazolyl tetrazolium (MTT) assay.RESULTS: The proportion of S-phase Chang liver cells transfected with pEGFP-N1/core was significantly lower than that of cells transfected with blank plasmid at three different times after transfection (all P NT > C191), and apoptosis was increased in cells transfected with pEGFP-N1/core as the transfection time increased (72 h > 48 h > 24 h).CONCLUSION: These results suggest that HCV genotype 1b core protein induces apoptosis, and inhibits cellcycle progression and proliferation of Chang liver cells.Different quasispecies core proteins of HCV genotype 1b might have some differences in the pathogenesis of HCV persistent infection and hepatocellular carcinoma.

  20. Core Knowledge Confusions among University Students

    Science.gov (United States)

    Lindeman, Marjaana; Svedholm, Annika M.; Takada, Mikito; Lonnqvist, Jan-Erik; Verkasalo, Markku

    2011-01-01

    Previous studies have demonstrated that university students hold several paranormal beliefs and that paranormal beliefs can be best explained with core knowledge confusions. The aim of this study was to explore to what extent university students confuse the core ontological attributes of lifeless material objects (e.g. a house, a stone), living…

  1. Children's Science Learning: A Core Skills Approach

    Science.gov (United States)

    Tolmie, Andrew K.; Ghazali, Zayba; Morris, Suzanne

    2016-01-01

    Background: Research has identified the core skills that predict success during primary school in reading and arithmetic, and this knowledge increasingly informs teaching. However, there has been no comparable work that pinpoints the core skills that underlie success in science. Aims and method: The present paper attempts to redress this by…

  2. Progress in Fabrication of Gold and Silver Nanoparticles Coated Core-shell Microspheres%金、银纳米粒子包覆核壳结构微球的制备与研究进展

    Institute of Scientific and Technical Information of China (English)

    王晨; 古宏晨

    2011-01-01

    金、银纳米粒子包覆的核-壳结构微球在众多领域具有许多潜在的应用功能,也是近几年来的一个研究热点。本文分析和讨论了金、银纳米粒子包覆的核-壳结构微球的制备方法,包括静电自组装法、原位还原法、晶种生长法、化学镀法、超声法、一步合成法等;简述了金、银纳米粒子包覆的核壳结构微球的优异性能及其应用,并对其发展前景进行了展望。%Gold and silver nanoparticles coated core-shell microspheres have drew much attention in many areas due to their diverse potential applications.In this paper,several fabrication strategies are analyzed and discussed,including the electrostatic self-assembly,in-situ reduction,seeding,electroless plating,ultrasonic method,and one-pot synthesis method.The outstanding properties and applications of gold and silver nanoparticles coated core-shell microspheres are briefly summarized and their prospect is also addressed.

  3. Aim for the Inner Life: Teaching Early Teens.

    Science.gov (United States)

    Regelski, Thomas A.

    1979-01-01

    Music study should be construed primarily as an experience of its feeling content. Taught so, it can reach for the inner core of the early adolescent, to pierce that sometimes hard outer surface that protects the vulnerable inner life. Attempts to intellectualize music with young teens are doomed. (Author/SJL)

  4. Matching Investigation between Instrument Precision and Aiming Method

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In the course of using precise visual instrument, aiming precision is an important parameter to analyze the measurement error. Usually, instrument calibrated error is set down as measurement error. In the paper, the precision theory of TC2003 theodolite is analyzed and some aiming experiments is done for different width line. Then, the relations between the width of line and aiming precision are shown by different aiming methods of two superposition solid lines and one line clipped by double lines. Finally, an effective method to improve aiming precision is proposed which adopts the aiming method of one line clipped by double lines.

  5. Engineered Magnetic Core-Shell Structures.

    Science.gov (United States)

    Alavi Nikje, Mir Mohammad; Vakili, Maryam

    2015-01-01

    In recent years, engineered magnetic core-shell structures are playing an important role in the wide range of various applications. These magnetic core-shell structures have attracted considerable attention because of their unique properties and various applications. Also, the synthesis of engineered magnetic core-shell structures has attracted practical interest because of potential applications in areas such as ferrofluids, medical imaging, drug targeting and delivery, cancer therapy, separations, and catalysis. So far a large number of engineered magnetic core-shell structures have been successfully synthesized. This review article focuses on the recent progress in synthesis and characterization of engineered magnetic core-shell structures. Also, this review gives a brief description of the various application of these structures. It is hoped that this review will play some small part in helping future developments in important field.

  6. Progress Report

    DEFF Research Database (Denmark)

    Duer, Karsten

    1999-01-01

    Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999.......Progress report describing the work carried out by the Danish participant in the ALTSET project in the period January 1999 to July 1999....

  7. k-core covers and the core

    NARCIS (Netherlands)

    Sanchez-Rodriguez, E.; Borm, Peter; Estevez-Fernandez, A.; Fiestras-Janeiro, G.; Mosquera, M.A.

    2015-01-01

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  8. Academic Rigor: The Core of the Core

    Science.gov (United States)

    Brunner, Judy

    2013-01-01

    Some educators see the Common Core State Standards as reason for stress, most recognize the positive possibilities associated with them and are willing to make the professional commitment to implementing them so that academic rigor for all students will increase. But business leaders, parents, and the authors of the Common Core are not the only…

  9. k-core covers and the core

    NARCIS (Netherlands)

    Sanchez-Rodriguez, E.; Borm, Peter; Estevez-Fernandez, A.; Fiestras-Janeiro, G.; Mosquera, M.A.

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  10. Cool Core Clusters from Cosmological Simulations

    CERN Document Server

    Rasia, E; Murante, G; Planelles, S; Beck, A M; Biffi, V; Ragone-Figueroa, C; Granato, G L; Steinborn, L K; Dolag, K

    2015-01-01

    We present results obtained from a set of cosmological hydrodynamic simulations of galaxy clusters, aimed at comparing predictions with observational data on the diversity between cool-core and non-cool-core clusters. Our simulations include the effects of stellar and AGN feedback and are based on an improved version of the Smoothed-Particle-Hydrodynamics code GADGET-3, which ameliorates gas mixing and better captures gas-dynamical instabilities by including a suitable artificial thermal diffusion. In this Letter, we focus our analysis on the entropy profiles, our primary diagnostic to classify the degree of cool-coreness of clusters, and on the iron profiles. In keeping with observations, our simulated clusters display a variety of behaviors in entropy profiles: they range from steadily decreasing profiles at small radii, characteristic of cool-core systems, to nearly flat core isentropic profiles, characteristic of non cool-core systems. Using observational criteria to distinguish between the two classes of...

  11. [Progress on transgenic mosquitoes].

    Science.gov (United States)

    Yang, Pin

    2011-04-30

    The genetically modified mosquitoes have been developed aiming to control mosquito-borne diseases by either reducing population sizes or replacing existing populations with vectors unable to transmit the disease. introduces some progress on the generation of transgenic mosquitoes and their fitness in wild population. This paper

  12. Progress of gold-coated core-shell magnetic nanoparticles%具有核-壳结构的金纳米包覆磁性纳米复合颗粒的研究进展

    Institute of Scientific and Technical Information of China (English)

    石运芹; 李梅金

    2012-01-01

    具有核-壳结构的金纳米包覆的磁性纳米粒子,既具有磁性纳米粒子的特点又增加了金纳米的表面化学性质,近年来受到研究人员的广泛关注。简要综述了近年来国内外制备2类核-壳结构的金包铁磁性纳米复合材料的研究进展及相关应用,并对其应用前景进行了展望。%Gold-coated core-shell magnetic nanoparticles,which have both the properties of magnetic nanoparticles and the surface chemical properties of Au nanoparticles,have attracted much attention in recent years.This review has summarized the preparation and the application of two kinds of these composite nanomaterials,and their prospect is also addressed.

  13. Progress on Ecological Tourism Research in China Based on the Literature of the Core Journals-measurement Analysis%国内生态旅游研究进展——基于核心期刊的文献计量分析

    Institute of Scientific and Technical Information of China (English)

    叶茜

    2012-01-01

    The datas from 1999 to 2011 in core journals published the 1699 paper measurement analysis, from the document Angle into our ecological tourism research progress. Ecological tourism research reveals the background of the subject distribution, institutions and regional distribution, and ecological tourism research to the core of the main research perspective and the authors, hot and funded is analyzed. Ecological Tourism Research Interdisciplinary Integration, regional distribution of imbalance, the core group of scholars not prominent research characteristics. The author presents view, proposed the ecological tourism research study to change attitude,enhance the academic team cooperation, funded to into ecological civilization social benefits.%通过对1999-2011年间发表在核心期刊上的1699篇论文进行计量分析,从文献学视角透视我国生态旅游研究的进展状况,揭示了生态旅游研究的学科背景分布、机构与地域分布特征,并且对生态旅游研究的核心作者群、主要研究角度与热点以及基金资助情况进行了分析。提出生态旅游研究具有学科交叉相融性、地域分布不均衡性、核心学者群不突出等研究特性,建议生态旅游研究亟待转变研究态度,加强学术团队合作,基金资助要转化为生态文明社会效益。

  14. Selection patterns, gender and friendship aim in classroom networks.

    NARCIS (Netherlands)

    Baerveldt, Chris; Van de Bunt, Gerhard G.; Vermande, Marjolijn M.

    2014-01-01

    The social networks of students, and the underlying processes of selection, can have strong effects on their psychological and academic adjustment. The effects of gender, friendship aim (intimacy or social activities) and the combination of gender and friendship aim on selection patterns (student’s

  15. Patriotism, history and the legitimate aims of American education

    NARCIS (Netherlands)

    Merry, M.S.

    2009-01-01

    This article argues that while an attachment to one's country is both natural and even partially justifiable, cultivating loyal patriotism in schools is untenable insofar as it conflicts with the legitimate aims of education. These aims include the epistemological competence necessary for ascertaini

  16. Patriotism, History and the Legitimate Aims of American Education

    Science.gov (United States)

    Merry, Michael S.

    2009-01-01

    This article argues that while an attachment to one's country is both natural and even partially justifiable, cultivating loyal patriotism in schools is untenable insofar as it conflicts with the legitimate aims of education. These aims include the epistemological competence necessary for ascertaining important truths germane to the various…

  17. The Aims of Education and the Leap of Freedom

    Science.gov (United States)

    Yun, SunInn

    2014-01-01

    This paper considers the place of freedom in discussions of the aims of education. Bearing in mind remarks of R.S. Peters to the affect that the singling out of aims can "fall into the hands of rationalistically minded curriculum planners", it begins by considering the views of Roland Reichenbach regarding Bildung and his account of this…

  18. Selection patterns, gender and friendship aim in classroom networks.

    NARCIS (Netherlands)

    Baerveldt, Chris; Van de Bunt, Gerhard G.; Vermande, Marjolijn M.

    2014-01-01

    The social networks of students, and the underlying processes of selection, can have strong effects on their psychological and academic adjustment. The effects of gender, friendship aim (intimacy or social activities) and the combination of gender and friendship aim on selection patterns (student’s

  19. Patriotism, history and the legitimate aims of American education

    NARCIS (Netherlands)

    Merry, M.S.

    2009-01-01

    This article argues that while an attachment to one's country is both natural and even partially justifiable, cultivating loyal patriotism in schools is untenable insofar as it conflicts with the legitimate aims of education. These aims include the epistemological competence necessary for

  20. The Aims of Education and the Leap of Freedom

    Science.gov (United States)

    Yun, SunInn

    2014-01-01

    This paper considers the place of freedom in discussions of the aims of education. Bearing in mind remarks of R.S. Peters to the affect that the singling out of aims can "fall into the hands of rationalistically minded curriculum planners", it begins by considering the views of Roland Reichenbach regarding Bildung and his account of this…

  1. An Analysis of Aims and the Educational "Event"

    Science.gov (United States)

    den Heyer, Kent

    2015-01-01

    In this article, the author explores key distinctions relevant to aims talk in education. He argues that present formulations of aims fail to adequately capture or speak to several overlapping domains involved in schooling: qualification, socialization, and the educational in the form of subjectification (Biesta, 2010). Drawing off Egan and Biesta…

  2. Movement planning of video and of manual aiming movements.

    Science.gov (United States)

    Bédard, Patrick; Proteau, Luc

    2005-01-01

    We studied aiming performance of adults for video- and manual aiming tasks when they had visual information about the location of the starting base or when they had not. In video-aiming, foveating the starting base and then the target prior to movement initiation (Foveation) resulted in less aiming bias and variability than when the starting base was not visible (PNV), or visible without the participants foveating it prior to movement initiation (PSV). In manual aiming, Foveation and PSV procedures resulted in identical results but reduced aiming bias and variability in comparison to the PNV procedures. The results indicate that participants had difficulty in transforming the locations of the starting base and of the target when seen on a vertical screen into an appropriate movement trajectory. Successive foveation of the starting base and of the target facilitated this transformation, resulting in direction variability being reduced by more than half in comparison to the PNV and PSV conditions. This suggests that in video-aiming the efference copy of the saccade can be used by the CNS to approximate the hand trajectory in the workspace and/or in joint coordinates (Jouffrais and Boussaoud, 1999). Hand trajectory could be readily available in manual aiming if the target location can be recoded directly in hand-coordinates as recently suggested by Buneo et al. (2002).

  3. A Critique of Core-Collapse Supernova Theory Circa 1997

    CERN Document Server

    Burrows, A

    1998-01-01

    There has been a new infusion of ideas in the study of the mechanism and early character of core--collapse supernovae. However, despite recent conceptual and computational progress, fundamental questions remain. Some are summarize herein.

  4. Progressive Business

    DEFF Research Database (Denmark)

    Christiansen, Christian O.

    2016-01-01

    Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015.......Guest Post to the Society for U.S. Intellectual History Blog. Brief introduction to the book Progressive Business: An Intellectual History of the Role of Business in American Society, Oxford U.P., 2015....

  5. Implementation of an Anesthesia Information Management System (AIMS)

    Science.gov (United States)

    Douglas, James R.; Ritter, Melody J.

    2011-01-01

    During the administration of anesthesia, the anesthesia provider has historically created a paper record, charted manually, that included extensive patient care–related data (vital signs, other parameters, etc) and commentaries. DocuSys, a proprietary anesthesia information management system (AIMS), creates an electronic version of the anesthesia record and provides additional information. It electronically captures data from clinical monitors and other sources, including scheduling applications and laboratory computers. The AIMS facilitates chart entries such as drug doses and case narratives. Benefits of an AIMS include improved legibility of the anesthesia record and greater efficiency in documentation efforts. Use of the AIMS assists the practitioner with decision support logic, such as the timing of antibiotic administration and the inclusion of legally required documentation. Upon case completion, the AIMS data are immediately available to other information systems, such as billing and medical records. Data can be made available from a single case or, more important, from thousands of cases to analyze variables such as efficiency of services, adherence to best practices, patient outcomes, and clinical research. The AIMS was deployed at the main campus of the Ochsner Health System on March 26, 2009. In this article, we discuss the issues involved in the AIMS implementation process: the successes, surprises, and continued challenges. PMID:21734847

  6. Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

    Directory of Open Access Journals (Sweden)

    Natsumi Maehara

    2014-10-01

    Full Text Available Hepatocellular carcinoma (HCC is a widespread fatal disease and the third most common cause of cancer deaths. Here, we show the potent anti-HCC effect of the circulating protein AIM. As in adipocytes, AIM is incorporated into normal hepatocytes, where it interferes with lipid storage. In contrast, AIM accumulates on the HCC cell surface and activates the complement cascade via inactivating multiple regulators of complement activation. This response provokes necrotic cell death specifically in AIM-bound HCC cells. Accordingly, AIM−/− mice were highly susceptible to steatosis-associated HCC development, whereas no AIM+/+ mouse developed the disease despite comparable liver inflammation and fibrosis in response to a long-term high-fat diet. Administration of AIM prevented tumor development in AIM−/− mice, and HCC induction by diethylnitrosamine was more prominent in AIM−/− than wild-type mice. These findings could be the basis for novel AIM-based therapeutic strategies for HCC.

  7. Implementation of an Anesthesia Information Management System (AIMS).

    Science.gov (United States)

    Douglas, James R; Ritter, Melody J

    2011-01-01

    During the administration of anesthesia, the anesthesia provider has historically created a paper record, charted manually, that included extensive patient care-related data (vital signs, other parameters, etc) and commentaries. DocuSys, a proprietary anesthesia information management system (AIMS), creates an electronic version of the anesthesia record and provides additional information. It electronically captures data from clinical monitors and other sources, including scheduling applications and laboratory computers. The AIMS facilitates chart entries such as drug doses and case narratives. Benefits of an AIMS include improved legibility of the anesthesia record and greater efficiency in documentation efforts. Use of the AIMS assists the practitioner with decision support logic, such as the timing of antibiotic administration and the inclusion of legally required documentation. Upon case completion, the AIMS data are immediately available to other information systems, such as billing and medical records. Data can be made available from a single case or, more important, from thousands of cases to analyze variables such as efficiency of services, adherence to best practices, patient outcomes, and clinical research. The AIMS was deployed at the main campus of the Ochsner Health System on March 26, 2009. In this article, we discuss the issues involved in the AIMS implementation process: the successes, surprises, and continued challenges.

  8. Comodules over semiperfect corings

    CERN Document Server

    Caenepeel, S

    2011-01-01

    We discuss when the Rat functor associated to a coring satisfying the left $\\alpha$-condition is exact. We study the category of comodules over a semiperfect coring. We characterize semiperfect corings over artinian rings and over qF-rings.

  9. Coring Sample Acquisition Tool

    Science.gov (United States)

    Haddad, Nicolas E.; Murray, Saben D.; Walkemeyer, Phillip E.; Badescu, Mircea; Sherrit, Stewart; Bao, Xiaoqi; Kriechbaum, Kristopher L.; Richardson, Megan; Klein, Kerry J.

    2012-01-01

    A sample acquisition tool (SAT) has been developed that can be used autonomously to sample drill and capture rock cores. The tool is designed to accommodate core transfer using a sample tube to the IMSAH (integrated Mars sample acquisition and handling) SHEC (sample handling, encapsulation, and containerization) without ever touching the pristine core sample in the transfer process.

  10. Organizational technologies for transforming care: measures and strategies for pursuit of IOM quality aims.

    Science.gov (United States)

    Gamm, Larry; Kash, Bita; Bolin, Jane

    2007-01-01

    Progress on the Institute of Medicine's (IOM's) 6 aims to bridge the "quality chasm" requires both measurement and the concerting of multiple organizational technologies. The basic thesis of this article is that rapid progress on the IOM's multiple aims calls for transformative change within and among healthcare organizations. The promise of a number of types of transformative approaches is closely linked to their ability to simultaneously build upon several organizational technologies: clinical, social, information, and administrative technologies. To encourage and advance such efforts, this article identifies illustrative measures of attainment of the IOM's 6 aims or targeted areas for improvement that reflect the contributions of the 4 organizational technologies. It discusses examples of relationships between the IOM aims and the organizational technologies considered. Finally, the article offers illustrations of the interplay of these organizational technologies and IOM aims-across an array of organizational innovations with transformative potential. Included among such innovations are information technology in the form of electronic medical records, computer-based physician order entry, and patient health records; organization-wide patient-centered cultural change such as Studer's Hardwiring Excellence; Six Sigma and Toyota Production Management/LEAN; major clinical technology change, for example, minimally invasive cardiac surgery and broader treatment innovations such as disease management.

  11. Evaluation and cultural adaptation of a German version of the AIMS2-SF questionnaire (German AIMS2-SF).

    NARCIS (Netherlands)

    Rosemann, T.J.; Korner, T.; Wensing, M.J.P.; Schneider, A.; Szecsenyi, J.

    2005-01-01

    OBJECTIVES: The aim of the study was to examine the validity of a translated and culturally adapted version of the Arthritis Impact Measurement Scales 2, Short Form (AIMS2-SF) in patients suffering from osteoarthritis (OA) in primary care. METHODS: A structured procedure was used for the translation

  12. Gender Advertisements in Magazines Aimed at African Americans: A Comparison to Their Occurrence in Magazines Aimed at Caucasians.

    Science.gov (United States)

    McLaughlin, Tara L.; Goulet, Nicole

    1999-01-01

    Analyzed more than 200 magazines to compare advertisements in magazines aimed at African Americans with advertisements in magazines aimed at Caucasians. Discusses results in terms of the demand characteristics implicit in gender advertisements and in terms of cultural differences in gender role expectations. (Author/SLD)

  13. Evaluation and cultural adaptation of a German version of the AIMS2-SF questionnaire (German AIMS2-SF).

    NARCIS (Netherlands)

    Rosemann, T.J.; Korner, T.; Wensing, M.J.P.; Schneider, A.; Szecsenyi, J.

    2005-01-01

    OBJECTIVES: The aim of the study was to examine the validity of a translated and culturally adapted version of the Arthritis Impact Measurement Scales 2, Short Form (AIMS2-SF) in patients suffering from osteoarthritis (OA) in primary care. METHODS: A structured procedure was used for the translation

  14. Americans aim to overhaul science teaching by 2061

    CERN Multimedia

    1990-01-01

    Project 2061 is a long-term initiative by the AAAS to reform classroom science. Deputy director Walter Gillespie claims that the aim is for schools to teach less content but teach it better (1/2 page).

  15. Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome

    Directory of Open Access Journals (Sweden)

    Deborah D Crane

    2014-08-01

    Full Text Available Activation of the inflammasome is important for the detection and clearance of cytosolic pathogens. In contrast to avirulent F. novicida (Fn, infection with virulent F. tularensis ssp tularensis does not trigger activation of the host AIM2 inflammasome. Here we show that differential activation of AIM2 following Francisella infection is due to sensitivity of each isolate to reactive oxygen species (ROS. ROS present at the outset of Fn infection contributes to activation of the AIM2 inflammasome, independent of NLRP3 and NADPH oxidase. Rather, mitochondrial ROS (mROS is critical for Fn stimulation of the inflammasome. This study represents the first demonstration of the importance of mROS in the activation of the AIM2 inflammasome by bacteria. Our results also demonstrate that bacterial resistance to mROS is a mechanism of virulence for early evasion of detection by the host.

  16. Refractive aim and visual outcome after phacoemulsification: A 2 ...

    African Journals Online (AJOL)

    2016-03-24

    Mar 24, 2016 ... Aim: To review the short‑term visual outcome of phacoemulsification in adults with uncomplicated ... social consequences.[2] In a ... visual impairment, respectively. ... skills and experience, who form the group practice, did the.

  17. Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review

    NARCIS (Netherlands)

    Bauer, M.E.; Muller, G.C.; Correa, B.L.; Vianna, P.; Turner, J.E.; Bosch, J.A.

    2013-01-01

    There is evidence suggesting that immunosenescence can be accelerated by external factors such as chronic stress. Here we review potential psychoneuroendocrine determinants of premature aging of the immune system and discuss available interventions aimed at attenuating immunosenescence. Chronic

  18. Psychoneuroendocrine interventions aimed at attenuating immunosenescence: a review

    NARCIS (Netherlands)

    Bauer, M.E.; Muller, G.C.; Correa, B.L.; Vianna, P.; Turner, J.E.; Bosch, J.A.

    2013-01-01

    There is evidence suggesting that immunosenescence can be accelerated by external factors such as chronic stress. Here we review potential psychoneuroendocrine determinants of premature aging of the immune system and discuss available interventions aimed at attenuating immunosenescence. Chronic stre

  19. Toolkit for local decision makers aims to strengthen environmental sustainability

    CSIR Research Space (South Africa)

    Murambadoro, M

    2011-11-01

    Full Text Available Members of the South African Risk and Vulnerability Atlas were involved in a meeting aimed at the development of a toolkit towards improved integration of climate change into local government's integrated development planning (IDP) process....

  20. Ethics and aims in psychotherapy: a contribution from Kant.

    Science.gov (United States)

    Callender, J S

    1998-08-01

    Psychotherapy is an activity which takes many forms and which has many aims. The present paper argues that it can be viewed as a form of moral suasion. Kant's concepts of free will and ethics are described and these are then applied to the processes and outcome of psychotherapy. It is argued that his ideas, by linking rationality, free will and ethics into a single philosophical system, offer a valuable theoretical framework for thinking about aims and ethical issues in psychotherapy.

  1. Design, synthesis and applications of core-shell, hollow core, and nanorattle multifunctional nanostructures.

    Science.gov (United States)

    El-Toni, Ahmed Mohamed; Habila, Mohamed A; Labis, Joselito Puzon; ALOthman, Zeid A; Alhoshan, Mansour; Elzatahry, Ahmed A; Zhang, Fan

    2016-02-01

    With the evolution of nanoscience and nanotechnology, studies have been focused on manipulating nanoparticle properties through the control of their size, composition, and morphology. As nanomaterial research has progressed, the foremost focus has gradually shifted from synthesis, morphology control, and characterization of properties to the investigation of function and the utility of integrating these materials and chemical sciences with the physical, biological, and medical fields, which therefore necessitates the development of novel materials that are capable of performing multiple tasks and functions. The construction of multifunctional nanomaterials that integrate two or more functions into a single geometry has been achieved through the surface-coating technique, which created a new class of substances designated as core-shell nanoparticles. Core-shell materials have growing and expanding applications due to the multifunctionality that is achieved through the formation of multiple shells as well as the manipulation of core/shell materials. Moreover, core removal from core-shell-based structures offers excellent opportunities to construct multifunctional hollow core architectures that possess huge storage capacities, low densities, and tunable optical properties. Furthermore, the fabrication of nanomaterials that have the combined properties of a core-shell structure with that of a hollow one has resulted in the creation of a new and important class of substances, known as the rattle core-shell nanoparticles, or nanorattles. The design strategies of these new multifunctional nanostructures (core-shell, hollow core, and nanorattle) are discussed in the first part of this review. In the second part, different synthesis and fabrication approaches for multifunctional core-shell, hollow core-shell and rattle core-shell architectures are highlighted. Finally, in the last part of the article, the versatile and diverse applications of these nanoarchitectures in

  2. Design, synthesis and applications of core-shell, hollow core, and nanorattle multifunctional nanostructures

    Science.gov (United States)

    El-Toni, Ahmed Mohamed; Habila, Mohamed A.; Labis, Joselito Puzon; Alothman, Zeid A.; Alhoshan, Mansour; Elzatahry, Ahmed A.; Zhang, Fan

    2016-01-01

    With the evolution of nanoscience and nanotechnology, studies have been focused on manipulating nanoparticle properties through the control of their size, composition, and morphology. As nanomaterial research has progressed, the foremost focus has gradually shifted from synthesis, morphology control, and characterization of properties to the investigation of function and the utility of integrating these materials and chemical sciences with the physical, biological, and medical fields, which therefore necessitates the development of novel materials that are capable of performing multiple tasks and functions. The construction of multifunctional nanomaterials that integrate two or more functions into a single geometry has been achieved through the surface-coating technique, which created a new class of substances designated as core-shell nanoparticles. Core-shell materials have growing and expanding applications due to the multifunctionality that is achieved through the formation of multiple shells as well as the manipulation of core/shell materials. Moreover, core removal from core-shell-based structures offers excellent opportunities to construct multifunctional hollow core architectures that possess huge storage capacities, low densities, and tunable optical properties. Furthermore, the fabrication of nanomaterials that have the combined properties of a core-shell structure with that of a hollow one has resulted in the creation of a new and important class of substances, known as the rattle core-shell nanoparticles, or nanorattles. The design strategies of these new multifunctional nanostructures (core-shell, hollow core, and nanorattle) are discussed in the first part of this review. In the second part, different synthesis and fabrication approaches for multifunctional core-shell, hollow core-shell and rattle core-shell architectures are highlighted. Finally, in the last part of the article, the versatile and diverse applications of these nanoarchitectures in

  3. [Content analysis of food adverts aimed at children].

    Science.gov (United States)

    Ponce-Blandón, José Antonio; Pabón-Carrasco, Manuel; Lomas-Campos, María de Las Mercedes

    To determine the contents and persuasive techniques used in processed food adverts aimed at children in Andalusia, comparing them with those aimed at adults. Study based on advert content analysis with two phases: a descriptive design phase and an analytical observational design phase. A sample of adverts from 60hours of broadcasting from the two most watched television channels in Andalusia. A total of 416 food and non-alcoholic beverage adverts were obtained, for 91 different products. Approximately 42.9% (n=39) was aimed at children and 53.8% (n=49) were products classified as "unhealthy". Unhealthy foods were more common in adverts for children (p <0.001). Significant differences were found between the ads aimed at adults and those aimed at children. Emotional and irrational persuasive resources such as fantasy (p <0.001), cartoons (p <0.001) or offering gifts with the purchase of the product (p=0.003) were observed more frequently in adverts for children. Food advertising aimed at children in Andalusia is mainly based on offering products with a low nutritional value and using persuasive resources based on fantasy or gifts. The message is focused on the incentive and not the food. More effective measures than the current self-regulatory systems must be put in place to counter these distorted adverts. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Banded transformer cores

    Science.gov (United States)

    Mclyman, C. W. T. (Inventor)

    1974-01-01

    A banded transformer core formed by positioning a pair of mated, similar core halves on a supporting pedestal. The core halves are encircled with a strap, selectively applying tension whereby a compressive force is applied to the core edge for reducing the innate air gap. A dc magnetic field is employed in supporting the core halves during initial phases of the banding operation, while an ac magnetic field subsequently is employed for detecting dimension changes occurring in the air gaps as tension is applied to the strap.

  5. Identifying ELIXIR Core Data Resources.

    Science.gov (United States)

    Durinx, Christine; McEntyre, Jo; Appel, Ron; Apweiler, Rolf; Barlow, Mary; Blomberg, Niklas; Cook, Chuck; Gasteiger, Elisabeth; Kim, Jee-Hyub; Lopez, Rodrigo; Redaschi, Nicole; Stockinger, Heinz; Teixeira, Daniel; Valencia, Alfonso

    2016-01-01

    The core mission of ELIXIR is to build a stable and sustainable infrastructure for biological information across Europe. At the heart of this are the data resources, tools and services that ELIXIR offers to the life-sciences community, providing stable and sustainable access to biological data. ELIXIR aims to ensure that these resources are available long-term and that the life-cycles of these resources are managed such that they support the scientific needs of the life-sciences, including biological research. ELIXIR Core Data Resources are defined as a set of European data resources that are of fundamental importance to the wider life-science community and the long-term preservation of biological data. They are complete collections of generic value to life-science, are considered an authority in their field with respect to one or more characteristics, and show high levels of scientific quality and service. Thus, ELIXIR Core Data Resources are of wide applicability and usage. This paper describes the structures, governance and processes that support the identification and evaluation of ELIXIR Core Data Resources. It identifies key indicators which reflect the essence of the definition of an ELIXIR Core Data Resource and support the promotion of excellence in resource development and operation. It describes the specific indicators in more detail and explains their application within ELIXIR's sustainability strategy and science policy actions, and in capacity building, life-cycle management and technical actions. The identification process is currently being implemented and tested for the first time. The findings and outcome will be evaluated by the ELIXIR Scientific Advisory Board in March 2017. Establishing the portfolio of ELIXIR Core Data Resources and ELIXIR Services is a key priority for ELIXIR and publicly marks the transition towards a cohesive infrastructure.

  6. A theoretical model to describe progressions and regressions for exercise rehabilitation.

    Science.gov (United States)

    Blanchard, Sam; Glasgow, Phil

    2014-08-01

    This article aims to describe a new theoretical model to simplify and aid visualisation of the clinical reasoning process involved in progressing a single exercise. Exercise prescription is a core skill for physiotherapists but is an area that is lacking in theoretical models to assist clinicians when designing exercise programs to aid rehabilitation from injury. Historical models of periodization and motor learning theories lack any visual aids to assist clinicians. The concept of the proposed model is that new stimuli can be added or exchanged with other stimuli, either intrinsic or extrinsic to the participant, in order to gradually progress an exercise whilst remaining safe and effective. The proposed model maintains the core skills of physiotherapists by assisting clinical reasoning skills, exercise prescription and goal setting. It is not limited to any one pathology or rehabilitation setting and can adapted by any level of skilled clinician.

  7. The HOR HEU/LEU core conversion

    Energy Technology Data Exchange (ETDEWEB)

    Gibcus, H.P.M.; Vries, J.W. de [Department of HOR-Development, IRI, Delft University of Technology, Delft (Netherlands); Leege, P.F.A. de [Department of Reactor Physics, IRI, Delft University of Technology, Delft (Netherlands)

    1999-07-01

    On March 16, 1998 the first two LEU (low enriched uranium) fuel elements were introduced in the HOR reactor of the Interfaculty Reactor Institute (IRI). At the moment the core consists of 5 LEU and 19 HEU (highly enriched uranium) fuel elements. It is anticipated that after about 13 core reload operations the HOR will be fully converted from HEU to LEU to a so called LEU compact core consisting of about 21 LEU fuel assemblies and as many beryllium reflector elements. The HOR HEU/LEU core conversion program, progress of the step-by-step transition phase, including comparisons of calculations and measurements, as well as the impact on the utilization of the reactor are discussed. (author)

  8. Uncertainty in aiming movements and its association to hand function

    Directory of Open Access Journals (Sweden)

    Flávia Priscila de Paiva Silva

    2015-09-01

    Full Text Available AbstractThe purpose of this study was to analyze the influence of the uncertainty of target location on the planning and execution of aiming movements performed towards the ipsilateral and contralateral directions by the right and left upper limbs. In addition, the association between the performance of aiming movements and the performance of functional manual tasks was investigated. Two tasks were proposed: with prior knowledge of the movement direction (simple reaction time or not (choice reaction time. The grip strength and manual dexterity were measured. The choice option in response (i.e. uncertainty influenced planning of the aiming movements, but not its execution, while movements performed towards the contralateral direction were worse in execution as compared to the ipsilateral direction. Manual dexterity was significantly correlated with reaction times, while the performance during movement execution was significantly correlated with handgrip/pinch strength.

  9. Aiming for a College Education: A Strategy for Scotland.

    Science.gov (United States)

    McPherson, Andrew; And Others

    The report reviews British Petroleum's "Aiming for College Education" program in Scotland, a 5-year program to raise the aspirations of young people for post-compulsory education and for higher education in particular. The program invites local higher education institutions to consider initiatives in four areas (promotion and marketing,…

  10. Aims and Formats of performance measurement at Danish Universities

    DEFF Research Database (Denmark)

    Raffnsøe-Møller, Morten

    2011-01-01

    Abstract This article traces the aims and formats of performance measurement of Danish Universities as they originate from the Ministry of Finance’s plan for governance of the public sector. The article further show that the fierce conflicts between central administration and the universities over...

  11. Philosophical Analysis, Research on Teaching, and Aim-Oriented Empiricism.

    Science.gov (United States)

    Popp, Jerome A.

    1980-01-01

    An attempt is made at providing cohesion and structure for a range of disparate activities and examining their interrelationships. Among concepts considered are: (1) the relationship of philosophic analysis in education; (2) the nature of pedagogical research; (3) the process-product paradigm; (4) aim-oriented empiricism; (5) the reduction thesis;…

  12. [Patient's aggression aimed at physicians. Legal interpretation of defense possibilities].

    Science.gov (United States)

    Patryn, Rafał

    2013-01-01

    The aim of the following study is to acquaint medical practitioners with legal possibilities of defense against patients'aggression. The occurrence of the described and discussed issue, namely the appearance of different forms of aggression aimed at physicians and other medical staff is a more and more frequently appearing phenomenon, which is very problematic, and difficult to interpret. The scope of the analysis has been limited to aggression of patients towards physicians only, as they are most often the aim of this aggression, and what should be emphasized, they lack practical and universal solutions and frequently also necessary knowledge to protect themselves against it. The idea behind this study is to present a rational solution to the afore mentioned situation, within legal limits. First, an outline of a conflict situation with a short specification of sources of aggression will be presented, than an appropriate legal taxonomy (including civil and criminal law) allowing for aid in such a situation will be offered and discussed.The authors will also present practical and legally permissible solutions aiming at defense, abandonment, and not allowing for the appearance of this reprehensible phenomenon.

  13. Anxiety and ironic effects in aiming at a far target

    NARCIS (Netherlands)

    Bakker, F.C.; Binsch, O.

    2011-01-01

    In far aiming the negative intention not to miss may ironically increase the tendency to do precisely that. Although cognitive constraints enhance the occurrence of ironic effects in the perceptual-motor domain the role of anxiety in inducing such effects has rarely been investigated while anxiety i

  14. Autonomy as the Guiding Aim of Entrepreneurship Education

    Science.gov (United States)

    van Gelderen, Marco

    2010-01-01

    Purpose: This paper has three purposes: first, to present a vision of entrepreneurship education that has the student's capacity for autonomous action as its ultimate aim; second, to convince the reader of the timeliness and relevance of such an approach; third, to outline how this can be implemented. Design/methodology/approach: The paper…

  15. Why the Aims of Education Cannot Be Settled

    Science.gov (United States)

    Hardarson, Atli

    2012-01-01

    The dominant model of curriculum design in the last century assumed that school education could be organized around aims, defined primarily in terms of students' behaviour. The credentials of this model were questioned by, among others, Lawrence Stenhouse, who pointed out that education serves purposes that cannot be stated in terms of behavioural…

  16. MayDay Colloquium 24: The Aims of Music Education

    Science.gov (United States)

    Elliott, David J.

    2013-01-01

    On June 20, 2012, Professor John Kratus welcomed the MayDay Group to Michigan State University for "Colloquium 24: The Aims of Music Education". On behalf of all members of the Mayday Group, the author wishes to extend his deepest gratitude to Professor Kratus and his colleagues at Michigan State for their extremely gracious and…

  17. Goal-Directed Aiming: Two Components but Multiple Processes

    Science.gov (United States)

    Elliott, Digby; Hansen, Steve; Grierson, Lawrence E. M.; Lyons, James; Bennett, Simon J.; Hayes, Spencer J.

    2010-01-01

    This article reviews the behavioral literature on the control of goal-directed aiming and presents a multiple-process model of limb control. The model builds on recent variants of Woodworth's (1899) two-component model of speed-accuracy relations in voluntary movement and incorporates ideas about dynamic online limb control based on prior…

  18. Do Normative Judgements Aim to Represent the World?

    NARCIS (Netherlands)

    Streumer, Bart

    2013-01-01

    Many philosophers think that normative judgements do not aim to represent the world. In this paper, I argue that this view is incompatible with the thought that when two people make conflicting normative judgements, at most one of these judgements is correct. I argue that this shows that normative j

  19. The Aims of Sex Education: Demoting Autonomy and Promoting Mutuality

    Science.gov (United States)

    McAvoy, Paula

    2013-01-01

    In this essay, Paula McAvoy critiques a commonly held view that teaching young people to be good choice makers should be a central aim of sex education. Specifically, she argues against David Archard's recommendation that sex educators ought to focus on the development of autonomy and teaching young people that "choice should be accorded…

  20. Do Normative Judgements Aim to Represent the World?

    NARCIS (Netherlands)

    Streumer, Bart

    2013-01-01

    Many philosophers think that normative judgements do not aim to represent the world. In this paper, I argue that this view is incompatible with the thought that when two people make conflicting normative judgements, at most one of these judgements is correct. I argue that this shows that normative j

  1. Core of Cloud Computing

    Directory of Open Access Journals (Sweden)

    Prof. C.P.Chandgude

    2017-04-01

    Full Text Available Advancement in computing facilities marks back from 1960’s with introduction of mainframes. Each of the computing has one or the other issues, so keeping this in mind cloud computing was introduced. Cloud computing has its roots in older technologies such as hardware virtualization, distributed computing, internet technologies, and autonomic computing. Cloud computing can be described with two models, one is service model and second is deployment model. While providing several services, cloud management’s primary role is resource provisioning. While there are several such benefits of cloud computing, there are challenges in adopting public clouds because of dependency on infrastructure that is shared by many enterprises. In this paper, we present core knowledge of cloud computing, highlighting its key concepts, deployment models, service models, benefits as well as security issues related to cloud data. The aim of this paper is to provide a better understanding of the cloud computing and to identify important research directions in this field

  2. The core paradox.

    Science.gov (United States)

    Kennedy, G. C.; Higgins, G. H.

    1973-01-01

    Rebuttal of suggestions from various critics attempting to provide an escape from the seeming paradox originated by Higgins and Kennedy's (1971) proposed possibility that the liquid in the outer core was thermally stably stratified and that this stratification might prove a powerful inhibitor to circulation of the outer core fluid of the kind postulated for the generation of the earth's magnetic field. These suggestions are examined and shown to provide no reasonable escape from the core paradox.

  3. K-core inflation

    OpenAIRE

    Alexander L. Wolman

    2011-01-01

    K-core inflation is a new class of underlying inflation measures. The two most popular measures of underlying inflation are core inflation and trimmed mean inflation. The former removes fixed categories of goods and services (food and energy) from the inflation calculation, and the latter removes fixed percentiles of the weighted distribution of price changes. In contrast, k-core inflation specifies a size of relative price change to be removed from the inflation calculation. Thus, the catego...

  4. Did We Get What We Aimed for 10 Years Ago?

    CERN Document Server

    Augustinus, A; Moreno, A; Kurepin, A N; De Cataldo, G; Pinazza, O; Rosinský, P; Lechman, M; Jirdén, L S

    2011-01-01

    The ALICE Detector Control System (DCS) is in charge of control and operation of one of the large high energy physics experiments at CERN in Geneva. The DCS design which started in 2000 was partly inspired by the control systems of the previous generation of HEP experiments at the LEP accelerator at CERN. However, the scale of the LHC experiments and the use of modern, "intelligent" hardware and the harsh operational environment led to an innovative system design. The overall architecture has been largely based on commercial products like PVSS SCADA system and OPC servers extended by frameworks. Windows has been chosen as the operating system platform for the core systems and Linux for the front-end devices. The concept of finite state machines has been deeply integrated into the system design and the design principles have been optimized and adapted to the expected operational needs. The ALICE DCS was designed, prototyped, and developed at a time when no experience with systems of similar s...

  5. CNGS Progress Report 2004

    CERN Document Server

    Bruno, L; Elsener, K; Gaillard, H; López-Hernandez, L A; Meddahi, M; Rangod, Stephane; Roesler, S; Spinks, Alan; Wilhelmsson, M; CERN. Geneva. AB Department

    2004-01-01

    The CNGS project is progressing according to schedule, with the aim to be ready for beam in spring 2006. In this paper, the project status and recent changes to the design of systems and components are summarized. The actions taken in response to the recommendations of the 2003 CNGS Review are described. This report has been drafted in view of the third CNGS Review, held in June 2004.

  6. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments. DESCRIPTION: The multisensor core logger measures...

  7. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments.DESCRIPTION: The multisensor core logger measures...

  8. Expert Systems Aimed at General Design of Projectiles

    Institute of Scientific and Technical Information of China (English)

    YUAN Zhi-hua; HOU Ni-na; HU Yu-hui

    2007-01-01

    Expert systems aimed at the general design of projectiles can implement a series of intelligent designs, such as the design of HE shell, the scheme expounded and proved, the emulation analysis and calculation, etc. Aiming at the product design feature, the expert system adopts the object-oriented knowledge representation and all kinds of inference control engines to describe and reason the relevant knowledge regarding the product through the microcomputer. It embodies the foundation of emulation analysis and simulated manufacturing of the shell. It makes use of the method that knowledge expression is combined with condition of inference to carry out the overall design and emulation and reference.The paper gives the ways through which the functions can be achieved, gives the modularization of reference and the design methods of systematization, puts forward the method of knowledge expression and working interface, and supplies a platform for similar products of the shell category that can be quickly designed.

  9. [Aiming at the chest, but hitting the back].

    Science.gov (United States)

    Zech, Wolf-Dieter; Axmann, Stefan; Siegenthaler, Lea; Kneubühl, Beat; Thali, Michael

    2011-01-01

    Gunshot injuries in the back may suggest the unjustified use of firearms. A wound in the back inflicted by a firearm should not automatically imply that the shooter aimed at the back. A previous study demonstrated that it is possible for men to turn their trunk faster than it takes for a shooter to fire or throw a hand-operated weapon. With a high speed motion camera the authors were able to demonstrate that it is also possible for women to turn their trunk fast enough, so that a shot in the back could have been aimed at the front of the body. This conclusion is also likely to apply to hand-operated or thrown weapons, since the velocity of their projectiles is considerably lower than that of firearms.

  10. Use of Probiotic Microorganisms for Bio-Protective Aims

    Directory of Open Access Journals (Sweden)

    Filiz YANGILAR

    2015-03-01

    Full Text Available It was known that some diseases can be treated as the result of the use of antibiotics in certain periods and at certain dosages while inactivating and deteriorating normal microorganisms performing useful activities in human metabolism (in especially intestinal flora. It was occured that after the use of antibiotics, some defects can be seen resulting from antibiotics (such as allergy, diarrhea, gas formation etc. With this aim, nutraceutics and functional food have gained importance over the last years and consumers began to be interested in probiotics, natural antioxidants, dietary fibres, products with low calorie and cholesterol contents, especially the products containing probioticbacteria. Bacteriocins produced by probiotic bacteria can play important roles as food protective and safeguarding since they can compete with unwanted or pathogen microorganisms survive in the media and colonize in intestines. In this review, is aimed to emphasis bioprotective compounds, advantages and disadvantages of biopreservation method and the importance of the mechanisms of probiotic microorganisms.

  11. Learning object for teacher training aimed to develop communication skills

    Directory of Open Access Journals (Sweden)

    Norma Esmeralda RODRÍGUEZ RAMÍREZ

    2014-06-01

    Full Text Available This article presents the results and reflections obtained across a research aimed to analyze the quality criteria of an opened learning object oriented to develop communication skills in order to be able to report and validate it according to its content, pedagogic structure, technological structure, graphical and textual language and usability to teacher training, in order to base it theoretically, pedagogically and technologically. The research question was: Which are the quality criteria that a learning object aimed to develop communication skills must cover? Under a quantitative approach, there were electronic questionnaires applied to: 34 Technological University teachers, eight experts about of communicative competence, teaching, technology and graphic design. The results indicated that some of the quality criteria of learning object are: the effective managing of the learning content, the balanced composition of his pedagogic structure, the technological structure efficiency and the proper managing of graphical and textual language.

  12. Action Information Management System (AIMS): a User's View

    Science.gov (United States)

    Wiskerchen, M.

    1984-01-01

    The initial approach used in establishing a user-defined information system to fulfill the needs of users at NASA Headquarters was unsuccessful in bringing this pilot endeaveor to full project status. The persistence of several users and the full involvement of the Ames Research Center were the ingredients needed to make the AIMS project a success. The lesson learned from this effort is that NASA should always work from its organizational strengths as a Headquarters-Center partnership.

  13. Implementation of an Anesthesia Information Management System (AIMS)

    OpenAIRE

    Douglas, James R.; Ritter, Melody J.

    2011-01-01

    During the administration of anesthesia, the anesthesia provider has historically created a paper record, charted manually, that included extensive patient care–related data (vital signs, other parameters, etc) and commentaries. DocuSys, a proprietary anesthesia information management system (AIMS), creates an electronic version of the anesthesia record and provides additional information. It electronically captures data from clinical monitors and other sources, including scheduling applicati...

  14. Simulation of AIMS measurements using rigorous mask 3D modeling

    Science.gov (United States)

    Chou, Chih-Shiang; Huang, Hsu-Ting; Chu, Fu-Sheng; Chu, Yuan-Chih; Huang, Wen-Chun; Liu, Ru-Gun; Gau, Tsai-Sheng

    2015-03-01

    Aerial image measurement system (AIMSTM) has been widely used for wafer level inspection of mask defects. Reported inspection flows include die-to-die (D2D) and die-to-database (D2DB) methods. For patterns that do not repeat in another die, only the D2DB approach is applicable. The D2DB method requires accurate simulation of AIMS measurements for a mask pattern. An optical vectorial model is needed to depict the mask diffraction effect in this simulation. To accurately simulate the imaging results, a rigorous electro-magnetic field (EMF) model is essential to correctly take account of the EMF scattering induced by the mask topography, which is usually called the mask 3D effect. In this study, the mask 3D model we use is rigorous coupled-wave analysis (RCWA), which calculates the diffraction fields from a single plane wave incidence. A hybrid Hopkins-Abbe method with RCWA is used to calculate the EMF diffraction at a desired accuracy level while keeping the computation time practical. We will compare the speed of the hybrid Hopkins-Abbe method to the rigorous Abbe method. The matching between simulation and experiment is more challenging for AIMS than CD-SEM because its measurements provide full intensity information. Parameters in the mask 3D model such as film stack thickness or film optical properties, is optimized during the fitting process. We will report the fitting results of AIMS images for twodimensional structures with various pitches. By accurately simulating the AIMS measurements, it provides a necessary tool to perform the mask inspection using the D2DB approach and to accurately predict the mask defects.

  15. Triple AIM evaluation and application in advanced node

    Science.gov (United States)

    Wang, Gary C.; Lio, En Chuan; Hung, Yuting; Chen, Charlie; Wang, Sybil; Weng, Tang Chun; Lin, Bill; Yu, Chun Chi

    2016-03-01

    A novel method on advanced node for IBO (Image Based Overlay) data extraction accuracy is demonstrated in this work, and here some special design in triple-AIM (Advanced Imaging Metrology) is able to realize the approach. Since triple AIM design has 3 locations left for patterning layers insertion, a new design with 2 layers locations, location-A (inner) and location-B (middle), are generated by 1st pattering, i.e. once lithography exposure, and the 2 marks grouping are formed on dielectric through lithography and etching process with a predetermined overlay "zero offset" through original mask layout design, as illustrated in Fig. (1). And then, as following top photo resist layer, assumed location-C (outer), lithography patterning process, PR coating, exposure and development complete, full triple-AIM patterns is generated, and 3 sets of overlay data could be obtained, A to B, C to B, C to A. Through re-calculating the overlay raw data of current (2nd patterning layer) to previous (1st patterning layer) layer by averaging [C to B] and [C to A], then theoretically the data extraction of sites would be more accuracy, since the variation of local marks signal, induced by inline process instability, could be minimized through the raw data averaging procedure. Moreover, from raw data [A to B], an extra monitor function for detections of the inline process variation, marks selection and recipe setting optimization could be obtained, since marks in [A] and [BB] locations are both generated in 1st patterning, and with the target "zero". So if the raw data [A to BB] is bigger or smaller than "zero" in some degree, there should be some process issue or marks condition setting error in triple-AIM design.

  16. Initiation Style Optimization of Aimed Warhead by Numerical Simulation

    Institute of Scientific and Technical Information of China (English)

    WEI Ji-feng; LI Na; WEN Yu-quan; WANG Wen-jie

    2008-01-01

    The kill characteristics of aimed warhead were studied.Emphasis on the improvement of initiation system,experiments and three dimensional numerical investigations were carried out.Simulation results of side three initiation points fit experiments well.Optimal initiation style is obtained through further simulation.It shows that the effective fragments and the effective kill energy of the optimal scheme increase 12.8%and 10.1%respectively.

  17. Implementation of an Anesthesia Information Management System (AIMS)

    OpenAIRE

    Douglas, James R.; Ritter, Melody J.

    2011-01-01

    During the administration of anesthesia, the anesthesia provider has historically created a paper record, charted manually, that included extensive patient care–related data (vital signs, other parameters, etc) and commentaries. DocuSys, a proprietary anesthesia information management system (AIMS), creates an electronic version of the anesthesia record and provides additional information. It electronically captures data from clinical monitors and other sources, including scheduling applicati...

  18. Electrostatic steering and beamlet aiming in large neutral beam injectors

    Science.gov (United States)

    Veltri, P.; Cavenago, M.; Chitarin, G.; Marcuzzi, D.; Sartori, E.; Serianni, G.; Sonato, P.

    2015-04-01

    Neutral beam injection is the main method for plasma heating in magnetic confinement fusion devices. In high energy injector (E>100 keV/amu), neutrals are obtained with reasonable efficiency by conversion of negative ions (H- or D-) via electron detachment reactions. In the case of ITER injectors, which shall operate at 1 MeV, a total ion current of ˜ 40 A is required to satisfy the heating power demand. Gridded electrodes are therefore used in the accelerator, so that 1280 negative ion beamlets are accelerated together. A carefully designed aiming system is required to control the beamlet trajectories, and to deliver their power on a focal point located several meters away from the beam source. In nowadays injectors, the aiming is typically obtained by aperture offset technique or by grid shaping. This paper discuss an alternative concept of beamlets aiming, based on an electrostatic "steerer" to be placed at the end of the accelerator. A feasibility study of this component is also presented, and its main advantages and drawbacks with respect to other methods are discussed.

  19. Electrostatic steering and beamlet aiming in large neutral beam injectors

    Energy Technology Data Exchange (ETDEWEB)

    Veltri, P., E-mail: pierluigi.veltri@igi.cnr.it; Chitarin, G.; Marcuzzi, D.; Sartori, E.; Serianni, G.; Sonato, P. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), Corso Stati Uniti 4 - 35127 Padova (Italy); Cavenago, M. [INFN-LNL, viale dell' Università n. 2, 35020 Legnaro (Italy)

    2015-04-08

    Neutral beam injection is the main method for plasma heating in magnetic confinement fusion devices. In high energy injector (E>100 keV/amu), neutrals are obtained with reasonable efficiency by conversion of negative ions (H- or D-) via electron detachment reactions. In the case of ITER injectors, which shall operate at 1 MeV, a total ion current of ∼ 40 A is required to satisfy the heating power demand. Gridded electrodes are therefore used in the accelerator, so that 1280 negative ion beamlets are accelerated together. A carefully designed aiming system is required to control the beamlet trajectories, and to deliver their power on a focal point located several meters away from the beam source. In nowadays injectors, the aiming is typically obtained by aperture offset technique or by grid shaping. This paper discuss an alternative concept of beamlets aiming, based on an electrostatic ”steerer” to be placed at the end of the accelerator. A feasibility study of this component is also presented, and its main advantages and drawbacks with respect to other methods are discussed.

  20. Refractive aiming corrections for satellite observation of stars

    Energy Technology Data Exchange (ETDEWEB)

    Vittitoe, C.N.; Schmidt, R.L.

    1997-03-01

    Standard references describe how apparent zenith angles differ from true zenith angles for observers on the Earth. In fact, correction formulae are available for aiming Earth-based sensors at stars; some corrections give variations as a function of observer altitude. Such corrections have not been available for observers in space. This report develops formulae appropriate for proper aiming from space-based sensors toward the relatively few stars that are near the Earth`s limb at any given time. These formulae correct for refractive effects and may be critical for steerable space-borne sensors with fields of view less than one degree, tasked to observe starlight passing near the Earth`s surface. Ray tracing in the U.S. Standard Atmosphere, 1976 including H{sub 2}O effects, is used to determine relations between the refracted tangent height, the apparent tangent height resulting from observation at the sensor, and the angle through which the detected rays have deviated. Analytic fits of the ray deviation as a function of apparent tangent height allows quick determination of corrections needed for a space-borne sensor. Using those results that apply in the plane of incidence and using the necessary coordinate rotations, alterations in the star`s apparent right ascension and declination are evaluated to improve the aim. Examples illustrate that alterations can be larger than one degree, with effects lasting up to a few minutes.

  1. Nuclear reactor core modelling in multifunctional simulators

    Energy Technology Data Exchange (ETDEWEB)

    Puska, E.K. [VTT Energy, Nuclear Energy, Espoo (Finland)

    1999-06-01

    The thesis concentrates on the development of nuclear reactor core models for the APROS multifunctional simulation environment and the use of the core models in various kinds of applications. The work was started in 1986 as a part of the development of the entire APROS simulation system. The aim was to create core models that would serve in a reliable manner in an interactive, modular and multifunctional simulator/plant analyser environment. One-dimensional and three-dimensional core neutronics models have been developed. Both models have two energy groups and six delayed neutron groups. The three-dimensional finite difference type core model is able to describe both BWR- and PWR-type cores with quadratic fuel assemblies and VVER-type cores with hexagonal fuel assemblies. The one- and three-dimensional core neutronics models can be connected with the homogeneous, the five-equation or the six-equation thermal hydraulic models of APROS. The key feature of APROS is that the same physical models can be used in various applications. The nuclear reactor core models of APROS have been built in such a manner that the same models can be used in simulator and plant analyser applications, as well as in safety analysis. In the APROS environment the user can select the number of flow channels in the three-dimensional reactor core and either the homogeneous, the five- or the six-equation thermal hydraulic model for these channels. The thermal hydraulic model and the number of flow channels have a decisive effect on the calculation time of the three-dimensional core model and thus, at present, these particular selections make the major difference between a safety analysis core model and a training simulator core model. The emphasis on this thesis is on the three-dimensional core model and its capability to analyse symmetric and asymmetric events in the core. The factors affecting the calculation times of various three-dimensional BWR, PWR and WWER-type APROS core models have been

  2. Inhibited coupling hollow-core photonic crystal fiber

    Science.gov (United States)

    Benabid, F.; Gérôme, F.; Vincetti, L.; Debord, B.; Alharbi, M.; Bradley, T.

    2014-02-01

    We review the recent progress on the enhanced inhibited coupling in kagome hollow-core photonic crystal fiber by introducing negative curvature in the fiber-core shape. We show that increasing the hypocycloid contour curvature leads to a dramatic decrease in transmission loss and optical overlap with the silica surround and to a single modedness. Fabricated hypocycloid-core hollow-core photonic crystal fibers with a transmission loss in the range of 20-40 dB/km and for a spectral range of 700 nm-2000 nm have now become typical.

  3. Balloon-Borne System Would Aim Instrument Toward Sun

    Science.gov (United States)

    Polites, M. E.

    1992-01-01

    Proposed system including digital control computer, control sensors, and control actuators aims telescope or other balloon-borne instrument toward Sun. Pointing system and instrument flown on gondola, suspended from balloon. System includes reaction wheel, which applies azimuthal control torques to gondola, and torque motor to apply low-frequency azimuthal torques between gondola and cable. Three single-axis rate gyroscopes measure yaw, pitch, and roll. Inclinometer measures roll angle. Two-axis Sun sensor measures deviation, in yaw and pitch, of attitude of instrument from line to apparent center of Sun. System provides initial coarse pointing, then maintains fine pointing.

  4. NASA tells physicists to aim for the stars

    CERN Multimedia

    MacIlwain, C

    1999-01-01

    Dan Goldin, administrator at NASA, suggested that the next generation of instruments for high-energy physics research should be built in space. This did not go down well at Fermilab where a case is being made for a new ground-based accelerator. Goldin's aim though was simply to tell the scientific community that NASA is prepared to spend big money on physics in space. NASA also wants to work more closely with the DOE and the NSF to support space-based experiments (1 page).

  5. Aims and methods of IRD expert group reviews

    OpenAIRE

    Beauvais, Marie-Laure

    2013-01-01

    This work, the seventh published in the IRD’s “Expert Group Review“ series, has the same general aims as the earlier ones and has been conducted by the same method, briefly summarized below. The IRD (Institut de recherche pour le développement, a State-funded research agency) conducts expert group reviews “to order“, to inform policy decisions and public debate on issues of importance to society. Putting its scientists’ research and knowledge at the disposal of the community is one of the IRD...

  6. Aims and methods of IRD expert group reviews in general

    OpenAIRE

    Beauvais, Marie-Laure

    2013-01-01

    This work, the sixth to be published in the IRD’s “Expert Group Review” series, has the same general aims as the earlier ones and has been conducted by the same method, briefly summarised below. The IRD (Institut de recherche pour le développement, a State-funded research agency) conducts expert group reviews “to order”, to inform policy decisions and public debate on issues of importance to society. Putting its scientists’ research and knowledge at the disposal of the community is one of the...

  7. Ice Core Investigations

    Science.gov (United States)

    Krim, Jessica; Brody, Michael

    2008-01-01

    What can glaciers tell us about volcanoes and atmospheric conditions? How does this information relate to our understanding of climate change? Ice Core Investigations is an original and innovative activity that explores these types of questions. It brings together popular science issues such as research, climate change, ice core drilling, and air…

  8. Making an Ice Core.

    Science.gov (United States)

    Kopaska-Merkel, David C.

    1995-01-01

    Explains an activity in which students construct a simulated ice core. Materials required include only a freezer, food coloring, a bottle, and water. This hands-on exercise demonstrates how a glacier is formed, how ice cores are studied, and the nature of precision and accuracy in measurement. Suitable for grades three through eight. (Author/PVD)

  9. Ice Core Investigations

    Science.gov (United States)

    Krim, Jessica; Brody, Michael

    2008-01-01

    What can glaciers tell us about volcanoes and atmospheric conditions? How does this information relate to our understanding of climate change? Ice Core Investigations is an original and innovative activity that explores these types of questions. It brings together popular science issues such as research, climate change, ice core drilling, and air…

  10. Iowa Core Annual Report

    Science.gov (United States)

    Iowa Department of Education, 2015

    2015-01-01

    One central component of a great school system is a clear set of expectations, or standards, that educators help all students reach. In Iowa, that effort is known as the Iowa Core. The Iowa Core represents the statewide academic standards, which describe what students should know and be able to do in math, science, English language arts, and…

  11. Mercury's core evolution

    Science.gov (United States)

    Deproost, Marie-Hélène; Rivoldini, Attilio; Van Hoolst, Tim

    2016-10-01

    Remote sensing data of Mercury's surface by MESSENGER indicate that Mercury formed under reducing conditions. As a consequence, silicon is likely the main light element in the core together with a possible small fraction of sulfur. Compared to sulfur, which does almost not partition into solid iron at Mercury's core conditions and strongly decreases the melting temperature, silicon partitions almost equally well between solid and liquid iron and is not very effective at reducing the melting temperature of iron. Silicon as the major light element constituent instead of sulfur therefore implies a significantly higher core liquidus temperature and a decrease in the vigor of compositional convection generated by the release of light elements upon inner core formation.Due to the immiscibility in liquid Fe-Si-S at low pressure (below 15 GPa), the core might also not be homogeneous and consist of an inner S-poor Fe-Si core below a thinner Si-poor Fe-S layer. Here, we study the consequences of a silicon-rich core and the effect of the blanketing Fe-S layer on the thermal evolution of Mercury's core and on the generation of a magnetic field.

  12. Combustion and Engine-Core Noise

    Science.gov (United States)

    Ihme, Matthias

    2017-01-01

    The implementation of advanced low-emission aircraft engine technologies and the reduction of noise from airframe, fan, and jet exhaust have made noise contributions from an engine core increasingly important. Therefore, meeting future ambitious noise-reduction goals requires the consideration of engine-core noise. This article reviews progress on the fundamental understanding, experimental analysis, and modeling of engine-core noise; addresses limitations of current techniques; and identifies opportunities for future research. After identifying core-noise contributions from the combustor, turbomachinery, nozzles, and jet exhaust, they are examined in detail. Contributions from direct combustion noise, originating from unsteady combustion, and indirect combustion noise, resulting from the interaction of flow-field perturbations with mean-flow variations in turbine stages and nozzles, are analyzed. A new indirect noise-source contribution arising from mixture inhomogeneities is identified by extending the theory. Although typically omitted in core-noise analysis, the impact of mean-flow variations and nozzle-upstream perturbations on the jet-noise modulation is examined, providing potential avenues for future core-noise mitigation.

  13. Hybrid Analysis of Engine Core Noise

    Science.gov (United States)

    O'Brien, Jeffrey; Kim, Jeonglae; Ihme, Matthias

    2015-11-01

    Core noise, or the noise generated within an aircraft engine, is becoming an increasing concern for the aviation industry as other noise sources are progressively reduced. The prediction of core noise generation and propagation is especially challenging for computationalists since it involves extensive multiphysics including chemical reaction and moving blades in addition to the aerothermochemical effects of heated jets. In this work, a representative engine flow path is constructed using experimentally verified geometries to simulate the physics of core noise. A combustor, single-stage turbine, nozzle and jet are modeled in separate calculations using appropriate high fidelity techniques including LES, actuator disk theory and Ffowcs-Williams Hawkings surfaces. A one way coupling procedure is developed for passing fluctuations downstream through the flowpath. This method effectively isolates the core noise from other acoustic sources, enables straightforward study of the interaction between core noise and jet exhaust, and allows for simple distinction between direct and indirect noise. The impact of core noise on the farfield jet acoustics is studied extensively and the relative efficiency of different disturbance types and shapes is examined in detail.

  14. Magnetohydrodynamic Convection in the Outer Core and its Geodynamic Consequences

    Science.gov (United States)

    Kuang, Weijia; Chao, Benjamin F.; Fang, Ming

    2004-01-01

    The Earth's fluid outer core is in vigorous convection through much of the Earth's history. In addition to generating and maintaining Earth s time-varying magnetic field (geodynamo), the core convection also generates mass redistribution in the core and a dynamical pressure field on the core-mantle boundary (CMB). All these shall result in various core-mantle interactions, and contribute to surface geodynamic observables. For example, electromagnetic core-mantle coupling arises from finite electrically conducting lower mantle; gravitational interaction occurs between the cores and the heterogeneous mantle; mechanical coupling may also occur when the CMB topography is aspherical. Besides changing the mantle rotation via the coupling torques, the mass-redistribution in the core shall produce a spatial-temporal gravity anomaly. Numerical modeling of the core dynamical processes contributes in several geophysical disciplines. It helps explain the physical causes of surface geodynamic observables via space geodetic techniques and other means, e.g. Earth's rotation variation on decadal time scales, and secular time-variable gravity. Conversely, identification of the sources of the observables can provide additional insights on the dynamics of the fluid core, leading to better constraints on the physics in the numerical modeling. In the past few years, our core dynamics modeling efforts, with respect to our MoSST model, have made significant progress in understanding individual geophysical consequences. However, integrated studies are desirable, not only because of more mature numerical core dynamics models, but also because of inter-correlation among the geophysical phenomena, e.g. mass redistribution in the outer core produces not only time-variable gravity, but also gravitational core-mantle coupling and thus the Earth's rotation variation. They are expected to further facilitate multidisciplinary studies of core dynamics and interactions of the core with other

  15. The AI&M procedure for learning from incomplete data

    DEFF Research Database (Denmark)

    Jaeger, Manfred

    2006-01-01

    We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account. Optimizing this profile likelihood poses two main difficult......We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account. Optimizing this profile likelihood poses two main...... difficulties: multiple (local) maxima, and its very high-dimensional parameter space. In this paper a new method is presented for optimizing the profile likelihood that addresses the second difficulty: in the proposed AI\\&M (adjusting imputation and maximization) procedure the optimization is performed...... by operations in the space of data completions, rather than directly in the parameter space of the profile likelihood. We apply the AI\\&M method to learning parameters for Bayesian networks. The method is compared against conservative inference, which takes into account each possible data completion...

  16. Halogen Bonding: An AIM Analysis of the Weak Interactions

    Institute of Scientific and Technical Information of China (English)

    ZOU, Jian-Wei; LU, Yun-Xiang; YU, Qing-Sen; ZHANG, Hua-Xin; JIANG, Yong-Jun

    2006-01-01

    A series of complexes formed between halogen-containing molecules and ammonia have been investigated by means of the atoms in molecules (AIM) approach to gain a deeper insight into halogen bonding. The existence of the halogen bond critical points (XBCP) and the values of the electron density (ρb) and Laplacian of electron density (▽2pb) at the XBCP reveal the closed-shell interactions in these complexes. Integrated atomic properties such as charge, energy, polarization moment, volume of the halogen bond donor atoms, and the corresponding changes (△) upon complexation have been calculated. The present calculations have demonstrated that the halogen bond represents different AIM properties as compared to the well-documented hydrogen bond. Both the electron density and the Laplacian of electron density at the XBCP have been shown to correlate well with the interaction energy, which indicates that the topological parameters at the XBCP can be treated as a good measure of the halogen bond strength.In addition, an excellent linear relationship between the interatomic distance d(X…N) and the logarithm of ρb has been established.

  17. Student Teachers’ Attitude towards Twitter for Educational Aims

    Directory of Open Access Journals (Sweden)

    Victoria I. Marín

    2014-07-01

    Full Text Available This paper presents an educational experience with 100 student teachers from different courses of the University of the Balearic Islands (Spain in which Twitter is used for various different activities. The aim of this experiment was to explore student teachers’ perceptions in order to value their attitude towards Twitter for educational aims. Afterwards, students were asked to write down their reflections on an eportfolio. Data was collected from their eportfolio evidence, which was analysed to review their attitude towards the use of Twitter for educational purposes and for their future teaching and professional development. The conclusions indicate the need to conduct different educational activities in which Twitter is used in various ways. In addition, conclusions reflect on the real impact of Twitter on students’ learning enhancement, in order to improve student teachers’ attitudes towards social media in education. Therefore, this article contributes to the body of existing research on the use of technology in education, specifically to the possibilities of the use of social media and microblogging in Teacher Education.

  18. Linking aims, paradigm and method in nursing research.

    Science.gov (United States)

    Houghton, Catherine; Hunter, Andrew; Meskell, Pauline

    2012-01-01

    To explore the use of paradigms as ontological and philosophical guides for conducting PhD research. A paradigm can help to bridge the aims of a study and the methods to achieve them. However, choosing a paradigm can be challenging for doctoral researchers: there can be ambiguity about which paradigm is suitable for a particular research question and there is a lack of guidance on how to shape the research process for a chosen paradigm. The authors discuss three paradigms used in PhD nursing research: post-positivism, interpretivism and pragmatism. They compare each paradigm in relation to its ontology, epistemology and methodology, and present three examples of PhD nursing research studies to illustrate how research can be conducted using these paradigms in the context of the research aims and methods. The commonalities and differences between the paradigms and their uses are highlighted. Creativity and flexibility are important when deciding on a paradigm. However, consistency and transparency are also needed to ensure the quality and rigour necessary for conducting nursing research. When choosing a suitable paradigm, the researcher should ensure that the ontology, epistemology and methodology of the paradigm are manifest in the methods and research strategies employed.

  19. Aims or purposes of school mediation in Spain

    Directory of Open Access Journals (Sweden)

    María-Isabel Viana-Orta

    2013-01-01

    Full Text Available Mediation continues to expand, both geographically and in terms of scope. Depending on its purpose, there are three main consolidated mediation models or schools worldwide: the Traditional-Linear Harvard model, which seeks to find an agreement between the parties; the Circular-Narrative model, which apart from the agreement also emphasizes communicational aspects; and the Transformational model, more focused on relational aspects between the parties than in the adoption of agreements. The aim of this study is to determine which is the goal or purpose of mediation, confining it to the school environment and to the Spanish context. A brief comparative study is presented to this end, in which the comparative units are all the Comunidades Autónomas [Autonomous Regions] that make up the Spanish territory (n = 17 and the variable compared is the aim or purpose of mediation in schools as established by all the regional rules on school life (n = 17 with the force of a decree.

  20. Mars' core and magnetism.

    Science.gov (United States)

    Stevenson, D J

    2001-07-12

    The detection of strongly magnetized ancient crust on Mars is one of the most surprising outcomes of recent Mars exploration, and provides important insight about the history and nature of the martian core. The iron-rich core probably formed during the hot accretion of Mars approximately 4.5 billion years ago and subsequently cooled at a rate dictated by the overlying mantle. A core dynamo operated much like Earth's current dynamo, but was probably limited in duration to several hundred million years. The early demise of the dynamo could have arisen through a change in the cooling rate of the mantle, or even a switch in convective style that led to mantle heating. Presently, Mars probably has a liquid, conductive outer core and might have a solid inner core like Earth.

  1. Core stability training on lower limb balance strength.

    Science.gov (United States)

    Dello Iacono, Antonio; Padulo, Johnny; Ayalon, Moshe

    2016-01-01

    This study aimed to assess the effects of core stability training on lower limbs' muscular asymmetries and imbalances in team sport. Twenty footballers were divided into two groups, either core stability or control group. Before each daily practice, core stability group (n = 10) performed a core stability training programme, while control group (n = 10) did a standard warm-up. The effects of the core stability training programme were assessed by performing isokinetic tests and single-leg countermovement jumps. Significant improvement was found for knee extensors peak torque at 3.14 rad · s(-1) (14%; P core stability group. The jump tests showed a significant reduction in the strength asymmetries in core stability group (-71.4%; P = 0.02) while a concurrent increase was seen in the control group (33.3%; P core exercises for optimal lower limbs strength balance development in young soccer players.

  2. The t-core of an s-core

    OpenAIRE

    Fayers, Matthew

    2010-01-01

    We consider the $t$-core of an $s$-core partition, when $s$ and $t$ are coprime positive integers. Olsson has shown that the $t$-core of an $s$-core is again an $s$-core, and we examine certain actions of the affine symmetric group on $s$-cores which preserve the $t$-core of an $s$-core. Along the way, we give a new proof of Olsson's result. We also give a new proof of a result of Vandehey, showing that there is a simultaneous $s$- and $t$-core which contains all others.

  3. The t-core of an s-core

    OpenAIRE

    Fayers, Matthew

    2010-01-01

    We consider the $t$-core of an $s$-core partition, when $s$ and $t$ are coprime positive integers. Olsson has shown that the $t$-core of an $s$-core is again an $s$-core, and we examine certain actions of the affine symmetric group on $s$-cores which preserve the $t$-core of an $s$-core. Along the way, we give a new proof of Olsson's result. We also give a new proof of a result of Vandehey, showing that there is a simultaneous $s$- and $t$-core which contains all others.

  4. PWR core stablity aganst xenon-induced spatial power oscillation

    Energy Technology Data Exchange (ETDEWEB)

    Moon, H.J.; Han, K.I. (Korea Advanced Energy Research Inst., Seoul (Republic of Korea))

    1982-06-01

    Stability of a PWR core against xenon-induced axial power oscillation is studied using one-dimensional xenon transient analysis code, DD1D, that has been developed and verified at KAERI. Analyzed by DD1D utilizing the Kori Unit 1 design and operating data is the sensitivity of axial stability in a PWR core to the changes in core physical parameters including core power level, moderator temperature coefficient, core inlet temperature, doppler power coefficient and core average burnup. Through the sensitivity study the Kori Unit 1 core is found to be stable against axial xenon oscillation at the beginning of cycle 1. But, it becomes less stable as burnup progresses, and unstable at the end of cycle. Such a decrease in stability is mainly due to combined effect of changes in axial power distribution, moderator temperature coefficient and doppler power coefficient as core burnup progresses. It is concluded from the stability analysis of the Kori Unit 1 core that design of a large PWR with high power density and increased dimension can not avoid xenon-induced axial power instabilites to some extents, especially at the end of cycle.

  5. Korrelasjon mellom core styrke, core stabilitet og utholdende styrke i core

    OpenAIRE

    Berg-Olsen, Andrea Marie; Fugelsøy, Eivor; Maurstad, Ann-Louise

    2010-01-01

    Formålet med studien var å se hvilke korrelasjon det er mellom core styrke, core stabilitet og utholdende styrke i core. Testingen bestod av tre hoveddeler hvor vi testet core styrke, core stabilitet og utholdende styrke i core. Innenfor core styrke og utholdende styrke i core ble tre ulike tester utført. Ved måling av core stabilitet ble det gjennomført kun en test. I core styrke ble isometrisk abdominal fleksjon, isometrisk rygg ekstensjon og isometrisk lateral fleksjon testet. Sit-ups p...

  6. Korrelasjon mellom core styrke, core stabilitet og utholdende styrke i core

    OpenAIRE

    Berg-Olsen, Andrea Marie; Fugelsøy, Eivor; Maurstad, Ann-Louise

    2010-01-01

    Formålet med studien var å se hvilke korrelasjon det er mellom core styrke, core stabilitet og utholdende styrke i core. Testingen bestod av tre hoveddeler hvor vi testet core styrke, core stabilitet og utholdende styrke i core. Innenfor core styrke og utholdende styrke i core ble tre ulike tester utført. Ved måling av core stabilitet ble det gjennomført kun en test. I core styrke ble isometrisk abdominal fleksjon, isometrisk rygg ekstensjon og isometrisk lateral fleksjon testet. Sit-ups p...

  7. Earth's inner core: Innermost inner core or hemispherical variations?

    NARCIS (Netherlands)

    Lythgoe, K. H.; Deuss, A.; Rudge, J. F.; Neufeld, J. A.

    2014-01-01

    The structure of Earth's deep inner core has important implications for core evolution, since it is thought to be related to the early stages of core formation. Previous studies have suggested that there exists an innermost inner core with distinct anisotropy relative to the rest of the inner core.

  8. Earth's inner core: Innermost inner core or hemispherical variations?

    NARCIS (Netherlands)

    Lythgoe, K. H.; Deuss, A.; Rudge, J. F.; Neufeld, J. A.

    2014-01-01

    The structure of Earth's deep inner core has important implications for core evolution, since it is thought to be related to the early stages of core formation. Previous studies have suggested that there exists an innermost inner core with distinct anisotropy relative to the rest of the inner core.

  9. An intervention aimed at reducing plagiarism in undergraduate nursing students.

    Science.gov (United States)

    Smedley, Alison; Crawford, Tonia; Cloete, Linda

    2015-05-01

    Plagiarism is a current and developing problem in the tertiary education sector where students access information and reproduce it as their own. It is identified as occurring in many tertiary level degrees including nursing and allied health profession degrees. Nursing specifically, is a profession where standards and ethics are required and honesty is paramount. The aim of this study was to evaluate the change in nursing student's knowledge and understanding of plagiarism before and after an educational intervention in their first semester of the Bachelor of nursing degree at a private college of higher education in Sydney, Australia. This study concluded that an educational intervention can increase knowledge and awareness of plagiarism among nursing students.

  10. Space Insect-Food Aiming at Mars Emigration

    Science.gov (United States)

    Katayama, Naomi; Hashimoto, Hirofumi; Yamashita, Masamichi; Takase, Yoshimi; Kawai, Mika; Space Agriculture Task Force

    We study space insect-food during 10 years. We are aiming at Mars emigration. In space agriculture, insect is the important creature which we cannot miss. It is necessary for the pollination of the plant, and it is rich to protein and lipid as food. We reported that silkworm, bee, grasshopper, snail, fly and termite (white ant) are insects necessary for astroponics in particular last time. We make clothes using silk thread, and the pupa becomes the food. In addition, the clothes can make food as protein when we need not to use it. The bee is a very important insect in the space agriculture, too. We calculated the nourishment ingredient of those insects and thought about ideal space foods which ara necessary for Mars emigration. We will introduce good balance space foods.

  11. Tourist animation aimed at developing rural tourism in Serbia

    Directory of Open Access Journals (Sweden)

    Đorđević Saša

    2016-01-01

    Full Text Available As a tourist destination, Serbia has some real opportunities to put priority on the rural tourism in relation to other forms of tourism. Subsequently, there is a need to make the rural tourism offer more attractive to tourists. Among other things, that offer includes a tourist animation, which is currently gaining in significance, emerging directly in and aimed at tourism development of rural areas. Therefore this paper deals first with the role and importance of tourism related knowledge about developing rural areas, and particularly the knowledge on animation; then follows the tourist animation as an attractive quality of rural areas' tourist offer; as well as the importance and the role of the government and tourist animation in the development of rural tourism, with particular emphasis on the necessity to educate and train tourist animators, as experts and professionals at the academic level.

  12. Microwave dielectric absorption spectroscopy aiming at novel dosimetry using DNAs

    Energy Technology Data Exchange (ETDEWEB)

    Izumi, Yoshinobu; Hirayama, Makoto; Matuo, Youichirou [Research Institute of Nuclear Engineering, University of Fukui, Fukui (Japan); Sunagawa, Takeyoshi [Fukui University of Technology, Fukui (Japan)

    2017-03-15

    We are developing L-band and S-band microwave dielectric absorption systems aiming novel dosimetry using DNAs, such as plasmid DNA and genomic DNA, and microwave technology. Each system is composed of a cavity resonator, analog signal generator, circulator, power meter, and oscilloscope. Since the cavity resonator is sensitive to temperature change, we have made great efforts to prevent the fluctuation of temperature. We have developed software for controlling and measurement. By using this system, we can measure the resonance frequency, f, and ΔQ (Q is a dimensionless parameter that describes how under-damped an oscillator or resonator is, and characterizes a resonator’s bandwidth relative to its center frequency) within about 3 minutes with high accuracy. This system will be expected to be applicable to DNAs evaluations and to novel dosimetric system.

  13. Visual Distraction: An Altered Aiming Spatial Response in Dementia

    Directory of Open Access Journals (Sweden)

    Elizabeth E. Galletta

    2012-06-01

    Full Text Available Background/Aims: Healthy individuals demonstrate leftward bias on visuospatial tasks such as line bisection, which has been attributed to right brain dominance. We investigated whether this asymmetry occurred in patients with probable dementia of the Alzheimer type (pAD which is associated with neurodegenerative changes affecting temporoparietal regions. Methods: Subjects with pAD and matched controls performed a line bisection task in near and far space under conditions of no distraction, left-sided visual distraction and right-sided visual distraction. Results: Participants with pAD manifested different motor-preparatory ‘aiming’ spatial bias than matched controls. There were significantly greater rightward ‘aiming’ motor-intentional errors both without distraction and with right-sided distraction. Conclusion: ‘Aiming’ motor-preparatory brain activity may be induced by distraction in pAD subjects as compared to typical visual-motor function in controls.

  14. Work in progress Tim Radford on research that aims to find a tiny error in Einstein's theory of special relativity

    CERN Multimedia

    Radford, T

    2004-01-01

    "Ben Varcoe wants to find a relatively small mistake in Einstein's theory of special relativity. To do this, he will slow light down from 300,000 km per second to 10 metres per second - about the speed of Darren Campbell - and see how it behaves" (1 page)

  15. Engineered inorganic core/shell nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Mélinon, Patrice, E-mail: patrice.melinon@univ-lyon1.fr [Institut Lumière matière Université Claude Bernard Lyon 1 et CNRS et OMNT, Domaine Scientifique de la Doua, Bâtiment Léon Brillouin, 43 Boulevard du 11 Novembre 1918, F 69622 Villeurbanne (France); Begin-Colin, Sylvie [IPCMS et OMNT, 23 rue du Loess BP 43, 67034 STRASBOURG Cedex 2 (France); Duvail, Jean Luc [IMN UMR 6502 et OMNT Campus Sciences : 2 rue de la Houssinire, BP32229, 44322 Nantes Cedex3 (France); Gauffre, Fabienne [SPM et OMNT : Institut des sciences chimiques de Rennes - UMR 6226, 263 Avenue du General Leclerc, CS 74205, 35042 RENNES Cedex (France); Boime, Nathalie Herlin [IRAMIS-NIMBE, Laboratoire Francis Perrin (CEA CNRS URA 2453) et OMNT, Bat 522, CEA Saclay, 91191 Gif sur Yvette Cedex (France); Ledoux, Gilles [Institut Lumière Matière Université Claude Bernard Lyon 1 et CNRS et OMNT, Domaine Scientifique de la Doua, Bâtiment Alfred Kastler 43 Boulevard du 11 Novembre 1918 F 69622 Villeurbanne (France); Plain, Jérôme [Universit de technologie de Troyes LNIO-ICD, CNRS et OMNT 12 rue Marie Curie - CS 42060 - 10004 Troyes cedex (France); Reiss, Peter [CEA Grenoble, INAC-SPrAM, UMR 5819 CEA-CNRS-UJF et OMNT, Grenoble cedex 9 (France); Silly, Fabien [CEA, IRAMIS, SPEC, TITANS, CNRS 2464 et OMNT, F-91191 Gif sur Yvette (France); Warot-Fonrose, Bénédicte [CEMES-CNRS, Université de Toulouse et OMNT, 29 rue Jeanne Marvig F 31055 Toulouse (France)

    2014-10-20

    It has been for a long time recognized that nanoparticles are of great scientific interest as they are effectively a bridge between bulk materials and atomic structures. At first, size effects occurring in single elements have been studied. More recently, progress in chemical and physical synthesis routes permitted the preparation of more complex structures. Such structures take advantages of new adjustable parameters including stoichiometry, chemical ordering, shape and segregation opening new fields with tailored materials for biology, mechanics, optics magnetism, chemistry catalysis, solar cells and microelectronics. Among them, core/shell structures are a particular class of nanoparticles made with an inorganic core and one or several inorganic shell layer(s). In earlier work, the shell was merely used as a protective coating for the core. More recently, it has been shown that it is possible to tune the physical properties in a larger range than that of each material taken separately. The goal of the present review is to discuss the basic properties of the different types of core/shell nanoparticles including a large variety of heterostructures. We restrict ourselves on all inorganic (on inorganic/inorganic) core/shell structures. In the light of recent developments, the applications of inorganic core/shell particles are found in many fields including biology, chemistry, physics and engineering. In addition to a representative overview of the properties, general concepts based on solid state physics are considered for material selection and for identifying criteria linking the core/shell structure and its resulting properties. Chemical and physical routes for the synthesis and specific methods for the study of core/shell nanoparticle are briefly discussed.

  16. [Social marketing--seduction with the aim of healthy behavior?].

    Science.gov (United States)

    Loss, J; Nagel, E

    2010-01-01

    SOCIAL MARKETING - SEDUCTION WITH THE AIM OF HEALTHY BEHAVIOR? Social marketing is the use of marketing principles to design and implement programs that promote socially beneficial behaviour change. Contrary to the marketing of consumption goods, social marketing does not deal with material products, but with behaviour, e. g. not smoking. This 'product' has a basic benefit (i. e. reduction of health risks in the long run), which is, however, difficult to convey. Therefore, the intended change in behaviour has to be related to a further reward which consists of symbolic goods, e. g. social appreciation or a better body feeling. The communication policy is essential for information on and motivation for the preventive issue. Social marketing campaigns whose development and management follow the principles of classical marketing can render preventive efforts more effective. In addition, social marketing can lead to a better quality management as compared to conventional preventive activities. These advantages can be explained by a) tailoring the campaign more specifically to the target group's needs and motives, b) presenting health risks more convincingly, and c) continuously analysing and evaluating the campaign and its effects. On the other hand, the marketing of preventive aims through mass media can bear several risks, as exemplified by different national and international public health campaigns. The necessity to communicate briefly and succinctly can lead to misleading simplifications and, in case of cancer screening, to the trivialization of a behaviour's consequences and adverse effects. Also, many campaigns do not intend to educate and inform, but try to persuade target persons of a certain behaviour, using emotions such as fear. This has led to social marketing being criticized as manipulation. Sometimes, social marketing campaigns cause stigma and discrimination of certain population subgroups, e. g. obese or HIV-positive people. Health promoters who plan

  17. IGCSE core mathematics

    CERN Document Server

    Wall, Terry

    2013-01-01

    Give your core level students the support and framework they require to get their best grades with this book dedicated to the core level content of the revised syllabus and written specifically to ensure a more appropriate pace. This title has been written for Core content of the revised Cambridge IGCSE Mathematics (0580) syllabus for first teaching from 2013. ? Gives students the practice they require to deepen their understanding through plenty of practice questions. ? Consolidates learning with unique digital resources on the CD, included free with every book. We are working with Cambridge

  18. Core shroud corner joints

    Science.gov (United States)

    Gilmore, Charles B.; Forsyth, David R.

    2013-09-10

    A core shroud is provided, which includes a number of planar members, a number of unitary corners, and a number of subassemblies each comprising a combination of the planar members and the unitary corners. Each unitary corner comprises a unitary extrusion including a first planar portion and a second planar portion disposed perpendicularly with respect to the first planar portion. At least one of the subassemblies comprises a plurality of the unitary corners disposed side-by-side in an alternating opposing relationship. A plurality of the subassemblies can be combined to form a quarter perimeter segment of the core shroud. Four quarter perimeter segments join together to form the core shroud.

  19. A Hunt for Massive Starless Cores

    CERN Document Server

    Kong, Shuo; Caselli, Paola; Fontani, Francesco; Liu, Mengyao; Butler, Michael J

    2016-01-01

    We carry out an ALMA $\\rm N_2D^+$(3-2) and 1.3~mm continuum survey towards 32 high mass surface density regions in seven Infrared Dark Clouds with the aim of finding massive starless cores, which may be the initial conditions for the formation of massive stars. Cores showing strong $\\rm N_2D^+$(3-2) emission are expected to be highly deuterated and indicative of early, potentially pre-stellar stages of star formation. We also present maps of these regions in ancillary line tracers, including C$^{18}$O(2-1), DCN(3-2) and DCO$^+$(3-2). Over 100 $\\rm N_2D^+$ cores are identified with our newly developed core-finding algorithm based on connected structures in position-velocity space. The most massive core has $\\gtrsim70\\:M_\\odot$ (potentially $\\sim170\\:M_\\odot$) and so may be representative of the initial conditions for massive star formation. The existence and dynamical properties of such cores constrain massive star formation theories. We measure the line widths and thus velocity dispersion of six of the cores ...

  20. Glass-clad semiconductor core optical fibers

    Science.gov (United States)

    Morris, Stephanie Lynn

    Glass-clad optical fibers comprising a crystalline semiconductor core have garnered considerable recent attention for their potential utility as novel waveguides for applications in nonlinear optics, sensing, power delivery, and biomedicine. As research into these fibers has progressed, it has become evident that excessive losses are limiting performance and so greater understanding of the underlying materials science, coupled with advances in fiber processing, is needed. More specifically, the semiconductor core fibers possess three performance-limiting characteristics that need to be addressed: (a) thermal expansion mismatches between crystalline core and glass cladding that lead to cracks, (b) the precipitation of oxide species in the core upon fiber cooling, which results from partial dissolution of the cladding glass by the core melt, and (c) polycrystallinity; all of which lead to scattering and increased transmission losses. This dissertation systematically studies each of these effects and develops both a fundamental scientific understanding of and practical engineering methods for reducing their impact. With respect to the thermal expansion mismatch and, in part, the dissolution of oxides, for the first time to our knowledge, oxide and non-oxide glass compositions are developed for a series of semiconductor cores based on two main design criteria: (1) matching the thermal expansion coefficient between semiconductor core and glass cladding to minimize cracking and (2) matching the viscosity-temperature dependences, such that the cladding glass draws into fiber at a temperature slightly above the melting point of the semiconductor in order to minimize dissolution and improve the fiber draw process. The x[Na 2O:Al2O3] + (100 - 2x)SiO2 glass compositional family was selected due to the ability to tailor the glass properties to match the aforementioned targets through slight variations in composition and adjusting the ratios of bridging and non-bridging oxygen

  1. Fluency: an aim in teaching and a criterion in assessment

    Directory of Open Access Journals (Sweden)

    Aud Marit Simensen

    2010-05-01

    Full Text Available This article investigates the concept ‘fluency’ from different perspectives. When fluency is an aim in teaching, a thorough comprehension of the concept among teachers is a prerequisite for appropriate planning of instruction, including the choice of appropriate classroom activities. When fluency is an assessment criterion, it is even more important that examiners have a shared perception of the concept. The present article starts by presenting common perceptions of the concept and goes on to explore some of the current research. Next, it provides a historical overview of the place of fluency in teaching theory and explains some of the preconditions for the inclusion of this concept among teaching objectives and assessment criteria. It will also, as an illustration, give an outline of the position of the concept over time in the Norwegian school system on the basis of an analysis of the relevant syllabuses. Finally, the article explicates the notion of language use as a complex cognitive skill and explores current method¬ological ideas about teaching towards fluency.

  2. A proper methodology aimed at surface wave tomography

    Directory of Open Access Journals (Sweden)

    J. Badal

    1997-06-01

    Full Text Available When applying a methodology for obtaining the 3D shear-wave velocity structure of a medium from surface wave dispersion data, the problem must be considered with caution since one inverts path-averaged velocities and the use of any inversion method entails some drawbacks such as lack of uniqueness, unwarranted stability and constraints affecting the data. In order to avoid the application of consecutive inversions and to overcome these drawbacks, we propose alternative mapping methods, for example spatial prediction methods, or else the use of an algorithm that, from a mathematical viewpoint, can be understood through the application of the orthogonal projection theorem onto convex sets (POCS. Among the first ones, we try inverse weighted distance interpolation. The POCS algorithm we have used discretises a second order differential equation for the velocity field with boundary conditions. All these imaging techniques aimed at volumetric modelling and the visualisation of data are discussed, and finally we show some results based on ray path velocities obtained previously by inversion of phase and group velocities of Rayleigh waves propagating across the Iberian peninsula.

  3. Alginate Immobilization of Metabolic Enzymes (AIME) for High ...

    Science.gov (United States)

    Alginate Immobilization of Metabolic Enzymes (AIME) for High-Throughput Screening Assays DE DeGroot, RS Thomas, and SO SimmonsNational Center for Computational Toxicology, US EPA, Research Triangle Park, NC USAThe EPA’s ToxCast program utilizes a wide variety of high-throughput screening (HTS) assays to assess chemical perturbations of molecular and cellular endpoints. A key criticism of using HTS assays for toxicity assessment is the lack of xenobiotic metabolism (XM) which precludes both metabolic detoxification as well as bioactivation of chemicals tested in vitro thereby mischaracterizing the potential risk posed by these chemicals. To address this deficiency, we have developed an extracellular platform to retrofit existing HTS assays with XM activity. This platform utilizes the S9 fraction of liver homogenate encapsulated in an alginate gel network which reduces the cytotoxicity caused by direct addition of S9 to cells in culture. Alginate microspheres containing encapsulated human liver S9 were cross-linked to solid supports extending from a 96-well plate lid and were assayed using a pro-luciferin substrate specific for CYP3A4 (IPA). We demonstrate that S9 was successfully encapsulated and remained enzymatically active post-encapsulation with 5-10X the CYP3A4 activity as compared to 1 µg solubilized human liver S9. Ketoconazole, a known inhibitor of human CYP3A4, inhibited CYP3A4 activity in a concentration-dependent manner (IC50: 0.27 µM) and inhibiti

  4. SaudiVeg ecoinformatics: Aims, current status and perspectives

    Directory of Open Access Journals (Sweden)

    Mohamed A. El-Sheikh

    2017-02-01

    Full Text Available During the last decade many electronic databases of vegetation plots were established in many countries around the world. These databases contain valuable phytosociological information assisting both governmental and NGO (Non-governmental organizations agencies to formulate strategies and on-ground plans to manage and protect nature resources. This paper provides an account on aims, current status and perspectives of building of a vegetation database for the Central Region (Najd of Saudi Arabia – the founding element of the Saudi Vegetation Database (SVD. The data stored by the database are sample plots (vegetation relevés collected according to the field techniques of the Braun-Blanquet approach (lists of taxa accompanied by semi-quantitative cover assessment, and are accompanied by general vegetation characteristics such as vegetation layering and cover, information on life-form of the recorded species, geographical coordinates, altitude, soil typology, topography and many more. More than 2900 vegetation-plot records (relevés have so far been collected in the Najd region; of these more than 2000 have already been stored using the Turboveg database platform. These field records cover many habitats such as depressions, wadis (dry river beds, agricultural lands, sand dunes, sabkhas, and ruderal habitats. The ecological information collected in the database is currently the largest set of vegetation data collated into a database in the Middle East. These data are of great importance for biodiversity studies in Saudi Arabia, since the region is recording a loss of biodiversity at a fast rate due to environmental problems such as global warming and land-use changes. We envisage that this database would catalyze further data collection on vegetation of the entire Arabian Peninsula, and shall serve as one of the most important datasets for classification and mapping of the vegetation of the Kingdom of Saudi Arabia.

  5. [Peptide synthesis aiming at elucidation and creation of protein functions].

    Science.gov (United States)

    Futaki, S

    1998-11-01

    The recent development of molecular biology has been elucidating outlines of the cross-talk of biomolecules. The understanding of the function of these biomolecules from the viewpoint of chemistry is now demanded not only for the understanding of biological systems but also for the creation of novel functional molecules. Here two topics are described about peptide synthesis aiming at the elucidation and the creation of protein functions. The first topic is the development of approaches for the synthesis of Tyr (SO3H)-containing peptides. Tyrosine sulfation is one of the most popular protein post-translational modifications. Synthetic peptides are of great help for the elucidation of the biological significance of tyrosine sulfation. We have developed two approaches for the efficient synthesis of tyrosine sulfate [Tyr (SO3H)]-containing peptides. The first approach employs a dimethylformamide-sulfur trioxide (DMF-SO3) complex as a sulfating agent and safety-catch protecting groups for the selective sulfation of tyrosine in the presence of serine. The second approach employs the direct introduction of Tyr(SO3H) into the peptide chain in the form of Fmoc-Tyr(SO3Na) followed by deprotection at 4 degrees C in trifluoroacetic acid. These approaches were successfully applied for the synthesis of cholecystokinin (CCK)-related peptides. The second topic deals with new approaches for the creation of artificial proteins through assembling alpha-helical peptides via selective disulfide or thioether formation. Approaches to assemble individual peptide segments on a peptide template were also developed. Four peptides corresponding to the transmembrane segments of the sodium channel (S4 in repeat I-IV) were assembled on a peptide template to give a protein having ion channel activity with rectification.

  6. A review of intervention studies aimed at household energy conservation

    Energy Technology Data Exchange (ETDEWEB)

    Abrahamse, W.; Steg, L.; Vlek, C.; Rothengatter, T. [Groningen Univ. (Netherlands). Dept. of Psychology

    2005-09-15

    This article reviews and evaluates the effectiveness of interventions aiming to encourage households to reduce energy consumption. Thirty-eight studies performed within the field of (applied) social and environmental psychology are reviewed, and categorized as involving either antecedent strategies (i.e. commitment, goal setting, information, modeling) or consequence strategies (i.e. feedback, rewards). Particular attention is given to the following evaluation criteria: (1) to what extent did the intervention result in behavioral changes and/or reductions in energy use, (2) were underlying behavioral determinants examined (e.g. knowledge, attitudes), (3) to what extent could effects be attributed to the interventions and, (4) were effects maintained over longer periods of time? Interestingly, most studies focus on voluntary behavior change, by changing individual knowledge and/or perceptions rather than changing contextual factors (i.e. pay-off structure) which may determine households' behavioral decisions. Interventions have been employed with varying degrees of success. Information tends to result in higher knowledge levels, but not necessarily in behavioral changes or energy savings. Rewards have effectively encouraged energy conservation, but with rather short-lived effects. Feedback has also proven its merits, in particular when given frequently. Some important issues cloud these conclusions, such as methodological problems. Also, little attention is given to actual environmental impact of energy savings. Often, an intervention's effectiveness is studied without examining underlying psychological determinants of energy use and energy savings. Also, it is not always clear whether effects were maintained over a longer period of time. Recommendations are given to further improve intervention planning and to enhance the effectiveness of interventions. (author)

  7. Construction of a narrative network aimed at implementing inclusive processes

    Directory of Open Access Journals (Sweden)

    Francesca Salis

    2017-01-01

    Full Text Available The concept of inclusion in its complex aspects aimed at overcoming barriers to learning and involvement has led this research in university, in the light of special pedagogy and didactics, on the basis of inclusion index parameters, detecting the levels of integrated planning with the territory. The purpose of this study is not limited to disability and to special education needs but goes further than that encompassing isolation and/or exclusions. As far as the university system is concerned, it becomes significant to enquire about the inclusion process, in this case by means of a narrative approach, bearing in mind that organizational and learning models, together with access modes may give rise to social exclusion.Università e territorio: costruzione di una rete narrativa per l’implementazione dei processi inclusiviIl costrutto di inclusione nelle sue complesse sfaccettature mirate al superamento delle barriere all’apprendimento e alla partecipazione, ha guidato il presente lavoro di ricerca in ambito universitario alla luce della pedagogia e didattica speciale, sulla base dei parametri dell’Index for Inclusion, rilevando i livelli di progettazione integrata con il territorio. Il suo raggio di azione non si limita alla disabilità ma abbraccia tutti i bisogni educativi speciali, e l’isolamento, la marginalizzazione e/o le esclusioni che ne derivano. Rispetto al sistema universitario è rilevante interrogarsi sul processo di inclusione, in questo caso sulla base dell’approccio narrativo, preso atto che il modello organizzativo e le modalità di accesso e formative possono essere causa di esclusione formativa e sociale.

  8. [Strategies aiming to control hyperphosphatemia in chronic kidney disease].

    Science.gov (United States)

    Ureña Torres, Pablo Antonio

    2017-04-01

    Chronic kidney disease is known to be associated with phosphate retention. The mechanisms are complex and the early increase in serum phosphate levels in chronic kidney disease is not strictly related to the dietary phosphate load or to the degree of phosphate retention. It also implicates the activity of intestinal sodium-phosphate cotransporters, the degree of bone turnover and the retention and/or phosphate release from the skeleton, and the feedback mechanisms regulating the phosphaturia. Indeed, the increase in serum phosphate levels is only a reflection of underlying complex mechanisms, and many important factors play a role including parathyroid hormone, vitamin D, fibroblast growth factor 23 (FGF23), and others. Hyperphosphatemia increases the risk of cardiovascular morbidity and mortality in chronic kidney disease as well as in subjects with normal renal function. Oral phosphate binders are prescribed in patients with chronic kidney disease and in those treated by dialysis, to prevent intestinal absorption of dietary phosphate and reduce serum phosphate. In prospective observational studies, they have been shown to decrease all-cause and cardiovascular mortality risk. However, different problems have been associated with currently available phosphate binders including the induction of a positive calcium balance and impaired outcomes with calcium-based phosphate binders or increased costs with non-calcium-based phosphate binders. Iron-based phosphate binders represent a new class of phosphate binders. The aim of this article is to provide an update review of the pathophysiological mechanisms leading and maintaining elevated serum phosphate levels in patients with chronic kidney disease and patients in dialysis, and the educational, nutritional, and therapeutic strategies that can be undertaken to control the hyperphosphatemia. Copyright © 2017 Association Société de néphrologie. Published by Elsevier Masson SAS. All rights reserved.

  9. Ready! Aim! Fire! targeting the right medical science journal.

    Science.gov (United States)

    Hardman, Timothy C; Serginson, James M

    2017-09-01

    Inadvertently submitting a paper to a journal that is unlikely to publish it is a waste of resources and ultimately delays dissemination of one's research. A high proportion of manuscripts are rejected by their author's first-choice journal. The aim of the present work was to review guidance provided within the literature for journal selection that might minimize the chance of manuscript rejection. We also consider papers that encompass more than one main medical science and describe the selection process that we used with a paper that was published in Cardiovascular Endocrinology. A database search (Embase, PubMed and Medworm) was performed for all articles published in the scientific literature providing guidance on journal selection. Articles were identified that either had journal selection as their principal topic or included journal selection as part of a broader discussion of publishing. The relative performance of four free-to-use, web-based applications that claim to provide guidance on journal selection was compared. The searches identified 286 hits, of which 249 were in English. Of these papers, 16 discussed journal selection and a further 10 articles were identified from citations within the original 16 articles. Only one article described a comprehensive model for submission decision-making. Identification of appropriate candidate journals by various web-based applications was erratic, with the Jane database providing the most robust suggestions. Our work suggests that little attention has been focused in the scientific literature on the mechanisms that authors use to select a journal for their work. Nevertheless, scientists for the most part seem to have a good sense of where their papers are most likely to be accepted. Beyond ensuring that a manuscript fulfils all the target journal's requirements, the literature suggests that it is important to have an objective view of the scientific contribution or 'value' of your work.

  10. Biospecimen Core Resource - TCGA

    Science.gov (United States)

    The Cancer Genome Atlas (TCGA) Biospecimen Core Resource centralized laboratory reviews and processes blood and tissue samples and their associated data using optimized standard operating procedures for the entire TCGA Research Network.

  11. iPSC Core

    Data.gov (United States)

    Federal Laboratory Consortium — The induced Pluripotent Stem Cells (iPSC) Core was created in 2011 to accelerate stem cell research in the NHLBI by providing investigators consultation, technical...

  12. Reference: -300CORE [PLACE

    Lifescience Database Archive (English)

    Full Text Available -300CORE Forde BG, Heyworth A, Pywell J, Kreis M Nucleotide sequence of a B1 hordein gene and the identifica...tion of possible upstream regulatory elements in endosperm storage protein genes fr

  13. Focusing on Core Business

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    China is regulating state-owned enterprises that are investing outside of their core business realms, concerned that poor investment decisions could lead to loss of state-owned assets, but some doubt the effect of the new regulation

  14. Organizing Core Tasks

    DEFF Research Database (Denmark)

    Boll, Karen

    Civil servants conduct the work which makes welfare states functions on an everyday bases: Police men police, school teachers teach, and tax inspectors inspect. Focus in this paper is on the core tasks of tax inspectors. The paper argues that their core task of securing the collection of revenue...... has remained much the same within the last 10 years. However, how the core task has been organized has changed considerable under the influence of various “organizing devices”. The paper focusses on how organizing devices such as risk assessment, output-focus, effect orientation, and treatment...... projects influence the organization of core tasks within the tax administration. The paper shows that the organizational transformations based on the use of these devices have had consequences both for the overall collection of revenue and for the employees’ feeling of “making a difference”. All in all...

  15. Progressive posterior cortical dysfunction

    Directory of Open Access Journals (Sweden)

    Fábio Henrique de Gobbi Porto

    Full Text Available Abstract Progressive posterior cortical dysfunction (PPCD is an insidious syndrome characterized by prominent disorders of higher visual processing. It affects both dorsal (occipito-parietal and ventral (occipito-temporal pathways, disturbing visuospatial processing and visual recognition, respectively. We report a case of a 67-year-old woman presenting with progressive impairment of visual functions. Neurologic examination showed agraphia, alexia, hemispatial neglect (left side visual extinction, complete Balint's syndrome and visual agnosia. Magnetic resonance imaging showed circumscribed atrophy involving the bilateral parieto-occipital regions, slightly more predominant to the right . Our aim was to describe a case of this syndrome, to present a video showing the main abnormalities, and to discuss this unusual presentation of dementia. We believe this article can contribute by improving the recognition of PPCD.

  16. Ecosystem-Based Adaptation for Food Security in the AIMS SIDS: Integrating External and Local Knowledge

    Directory of Open Access Journals (Sweden)

    Jessica Mercer

    2014-08-01

    Full Text Available This paper critically reviews ecosystem-based adaptation (EbA approaches for food security under climate change, specifically for the Small Island Developing States (SIDS comprising the Africa, Indian Ocean, Mediterranean and South China Sea (AIMS region. The focus is on integrating different knowledge forms. An analysis of current EbA approaches for food security is undertaken, alongside a review of methodologies for integrating local and external knowledge. Key gaps and actions for EbA for food security in the AIMS region, and potentially further afield, are identified. The gaps indicate the lack of coherence in AIMS SIDS approaching food security, in terms of policies and actions not reflecting the ecosystem-food-climate nexus, the lack of a regional framework despite similarities amongst the SIDS, and the infrequency with which knowledge integration occurs. To fill these gaps, suggested actions highlight knowledge identification and combination, learning from others and from history, using local champions, and regularly monitoring and evaluating progress. These actions will push forward the EbA agenda through improved development and use of knowledge, better connections amongst the AIMS SIDS and farther afield, and more local-national-regional collaboration.

  17. Aiming at Targets: The Autobiography of Robert C. Seamans, Jr.

    Science.gov (United States)

    Seamans, Robert C., Jr.

    1996-01-01

    Bob Seamans originally was inspired to write this book for his family and friends. That is a large audience. By his own count his immediate family numbers twenty-four, not counting brothers and cousins and their families. His friends are uncounted but surely run to hundreds. As one of them and as a colleague at NASA, I am pleased and honored that he asked me to write this foreword. While written in Bob's unique and informal style, this autobiography has significance for many readers beyond his large circles of family and friends. Leaders and students of large, complex technological endeavors should be able to learn much from reading how Bob faced the daunting technical and management challenges in his career. As the title of this book implies, Bob has always set high goals for himself and then kept his eyes focused on both the necessary details and the broader picture. His ability to shift smoothly among jobs that required seemingly disparate abilities and skills speaks volumes about his insight, dedication, and enthusiasm for achievement. The book spans a truly remarkable life story. Bob first takes us through his growing up, education, and early professional and family life. Next he focuses on the crucial years when he was the general manager of NASA. Then he moves on to his career in the top jobs at the Air Force, the National Academy of Engineering, and the Energy Research and Development Administration. Finally, he touches on his later leadership activities in the academic and business worlds. Aiming at Targets is a series of fascinating topical vignettes covering his professional life. Taken together, like broad brushstrokes in an impressionist painting, they give a better picture of Bob Seamans and his work than a detailed recitation of facts and dates could hope to do. This is a cheerful account of an interesting and successful career. The book is full of good stories, with many memorable characters. Like the proverbial sundial, it counts the sunny hours

  18. Nisin Production Utilizing Skimmed Milk Aiming to Reduce Process Cost

    Science.gov (United States)

    Jozala, Angela Faustino; de Andrade, Maura Sayuri; de Arauz, Luciana Juncioni; Pessoa, Adalberto; Penna, Thereza Christina Vessoni

    Nisin is a natural additive for conservation of food, pharmaceutical, and dental products and can be used as a therapeutic agent. Nisin inhibits the outgrowth of spores, the growth of a variety of Gram-positive and Gram-negative bacteria. This study was performed to optimize large-scale nisin production in skimmed milk and subproducts aiming at low-costs process and stimulating its utilization. Lactococcus lactis American Type Culture Collection (ATCC) 11454 was developed in a rotary shaker (30°C/36 h/100 rpm) in diluted skimmed milk and nisin activity, growth parameters, and media components were also studied. Nisin activity in growth media was expressed in arbitrary units (AU/mL) and converted to standard nisin concentration (Nisaplin®, 25 mg of pure nisin is 1.0×106 AU/mL). Nisin activity in skimmed milk 2.27 gtotal solids was up to threefold higher than transfers in skimmed milk 4.54 gtotal solids and was up to 85-fold higher than transfers in skimmed milk 1.14 gtotal solids. L. lactis was assayed in a New Brunswick fermentor with 1.5 L of diluted skimmed milk (2.27 gtotal solids) and airflow of 1.5 mL/min (30°C/36/200 rpm), without pH control. In this condition nisin activity was observed after 4 h (45.07 AU/mL) and in the end of 36 h process (3312.07 AU/mL). This work shows the utilization of a low-cost growth medium (diluted skimmed milk) to nisin production with wide applications. Furthermore, milk subproducts (milk whey) can be exploited in nisin production, because in Brazil 50% of milk whey is disposed with no treatment in rivers and because of high organic matter concentrations it is considered an important pollutant. In this particular case an optimized production of an antimicrobial would be lined up with industrial disposal recycling.

  19. Information science and its core concepts

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2013-01-01

    , what its aim is, what its core concepts are, what kinds of problems we try to solve, and what kinds of theories, metatheories, and related disciplines are the most important ones for us. Some people tend to regard IS as a branch of computer science or the cognitive sciences, while others tend...

  20. Geodynamo Modeling of Core-Mantle Interactions

    Science.gov (United States)

    Kuang, Wei-Jia; Chao, Benjamin F.; Smith, David E. (Technical Monitor)

    2001-01-01

    Angular momentum exchange between the Earth's mantle and core influences the Earth's rotation on time scales of decades and longer, in particular in the length of day (LOD) which have been measured with progressively increasing accuracy for the last two centuries. There are four possible coupling mechanisms for transferring the axial angular momentum across the core-mantle boundary (CMB): viscous, magnetic, topography, and gravitational torques. Here we use our scalable, modularized, fully dynamic geodynamo model for the core to assess the importance of these torques. This numerical model, as an extension of the Kuang-Bloxham model that has successfully simulated the generation of the Earth's magnetic field, is used to obtain numerical results in various physical conditions in terms of specific parameterization consistent with the dynamical processes in the fluid outer core. The results show that depending on the electrical conductivity of the lower mantle and the amplitude of the boundary topography at CMB, both magnetic and topographic couplings can contribute significantly to the angular momentum exchange. This implies that the core-mantle interactions are far more complex than has been assumed and that there is unlikely a single dominant coupling mechanism for the observed decadal LOD variation.

  1. The Dynamics of Massive Starless Cores

    Science.gov (United States)

    Tan, Jonathan; Caselli, P.; Fontani, F.; Kong, S.; Butler, M. J.

    2012-05-01

    Progress towards resolving a decade-long debate about how massive stars form can be made by determining if massive starless cores exist in a state of near virial equilibrium. These are the initial conditions invoked by the Core Accretion model of McKee & Tan (2003). Alternatively, the Competitive Accretion model of Bonnell et al. (2001) requires sub-virial conditions. We have identified 4 prime examples of massive ( 50 Msun) cores from mid-infrared (MIR) extinction mapping (Butler & Tan 2009, 2012) of Infrared Dark Clouds. We have found spectacularly high deuterated fractions of N_2H+ of 0.5 in these objects with the IRAM 30m telescope (Fontani et al. 2011). Thus N_2D+ is expected to be an excellent tracer of the kinematics of these cold, dark cores, where most other molecular tracers are thought to be depleted from the gas phase. We report on ALMA Cycle 0 Compact Configuration Band 6 observations of these 4 cores that probe the N_2D+(3-2) line on scales from 9" down to 2.3", well-matched to the structures we see in MIR extinction and discuss their implications for massive star formation theories.

  2. Fuel management strategy for the compact core design of RSG GAS (MPR-30)

    Energy Technology Data Exchange (ETDEWEB)

    Sembiring, T.M.; Liem, P.H.; Tukiran, S. [National Nuclear Energy Agency (Batan), PUSPIPTEK-Serpong Tangerang (Indonesia)

    2000-07-01

    The rearrangement of the core configuration of the RSG GAS reactor to obtain a compact core is in progress. A fuel management strategy is proposed for the equilibrium compact core of this reactor by reducing the number of in-core irradiation positions. The reduced irradiation positions are based on the activities during 12 years operation. The obtained compact core gives significant extension of the operation cycle length so that the reactor availability and utilization can be enhanced. The equilibrium compact silicide core obtained met the imposed design constraints and safety requirements. (author)

  3. Packing in protein cores

    Science.gov (United States)

    Gaines, J. C.; Clark, A. H.; Regan, L.; O'Hern, C. S.

    2017-07-01

    Proteins are biological polymers that underlie all cellular functions. The first high-resolution protein structures were determined by x-ray crystallography in the 1960s. Since then, there has been continued interest in understanding and predicting protein structure and stability. It is well-established that a large contribution to protein stability originates from the sequestration from solvent of hydrophobic residues in the protein core. How are such hydrophobic residues arranged in the core; how can one best model the packing of these residues, and are residues loosely packed with multiple allowed side chain conformations or densely packed with a single allowed side chain conformation? Here we show that to properly model the packing of residues in protein cores it is essential that amino acids are represented by appropriately calibrated atom sizes, and that hydrogen atoms are explicitly included. We show that protein cores possess a packing fraction of φ ≈ 0.56 , which is significantly less than the typically quoted value of 0.74 obtained using the extended atom representation. We also compare the results for the packing of amino acids in protein cores to results obtained for jammed packings from discrete element simulations of spheres, elongated particles, and composite particles with bumpy surfaces. We show that amino acids in protein cores pack as densely as disordered jammed packings of particles with similar values for the aspect ratio and bumpiness as found for amino acids. Knowing the structural properties of protein cores is of both fundamental and practical importance. Practically, it enables the assessment of changes in the structure and stability of proteins arising from amino acid mutations (such as those identified as a result of the massive human genome sequencing efforts) and the design of new folded, stable proteins and protein-protein interactions with tunable specificity and affinity.

  4. Inner core structure behind the PKP core phase triplication

    NARCIS (Netherlands)

    Blom, Nienke A.; Deuss, Arwen; Paulssen, Hanneke; Waszek, Lauren

    2015-01-01

    The structure of the Earth's inner core is not well known between depths of ∼100–200 km beneath the inner core boundary. This is a result of the PKP core phase triplication and the existence of strong precursors to PKP phases, which hinder the measurement of inner core compressional PKIKP waves at e

  5. Inner core structure behind the PKP core phase triplication

    NARCIS (Netherlands)

    Blom, Nienke A.; Deuss, Arwen; Paulssen, Hanneke; Waszek, Lauren

    The structure of the Earth's inner core is not well known between depths of ∼100–200 km beneath the inner core boundary. This is a result of the PKP core phase triplication and the existence of strong precursors to PKP phases, which hinder the measurement of inner core compressional PKIKP waves at

  6. Pressure Core Characterization

    Science.gov (United States)

    Santamarina, J. C.

    2014-12-01

    Natural gas hydrates form under high fluid pressure and low temperature, and are found in permafrost, deep lakes or ocean sediments. Hydrate dissociation by depressurization and/or heating is accompanied by a multifold hydrate volume expansion and host sediments with low permeability experience massive destructuration. Proper characterization requires coring, recovery, manipulation and testing under P-T conditions within the stability field. Pressure core technology allows for the reliable characterization of hydrate bearing sediments within the stability field in order to address scientific and engineering needs, including the measurement of parameters used in hydro-thermo-mechanical analyses, and the monitoring of hydrate dissociation under controlled pressure, temperature, effective stress and chemical conditions. Inherent sampling effects remain and need to be addressed in test protocols and data interpretation. Pressure core technology has been deployed to study hydrate bearing sediments at several locations around the world. In addition to pressure core testing, a comprehensive characterization program should include sediment analysis, testing of reconstituted specimens (with and without synthetic hydrate), and in situ testing. Pressure core characterization technology can be used to study other gas-charged formations such as deep sea sediments, coal bed methane and gas shales.

  7. Elevated skin and core temperatures both contribute to reductions in tolerance to a simulated haemorrhagic challenge.

    Science.gov (United States)

    Pearson, James; Lucas, Rebekah A I; Schlader, Zachary J; Gagnon, Daniel; Crandall, Craig G

    2017-02-01

    What is the central question of this study? Combined increases in skin and core temperatures reduce tolerance to a simulated haemorrhagic challenge. The aim of this study was to examine the separate and combined influences of increased skin and core temperatures upon tolerance to a simulated haemorrhagic challenge. What is the main finding and its importance? Skin and core temperatures increase during many occupational settings, including military procedures, in hot environments. The study findings demonstrate that both increased skin temperature and increased core temperature can impair tolerance to a simulated haemorrhagic challenge; therefore, a soldier's tolerance to haemorrhagic injury is likely to be impaired during any military activity that results in increased skin and/or core temperatures. Tolerance to a simulated haemorrhagic insult, such as lower-body negative pressure (LBNP), is profoundly reduced when accompanied by whole-body heat stress. The aim of this study was to investigate the separate and combined influence of elevated skin (Tskin ) and core temperatures (Tcore ) on LBNP tolerance. We hypothesized that elevations in Tskin as well as Tcore would both contribute to reductions in LBNP tolerance and that the reduction in LBNP tolerance would be greatest when both Tskin and Tcore were elevated. Nine participants underwent progressive LBNP to presyncope on four occasions, as follows: (i) control, with neutral Tskin (34.3 ± 0.5°C) and Tcore (36.8 ± 0.2°C); (ii) primarily skin hyperthermia, with high Tskin (37.6 ± 0.2°C) and neutral Tcore (37.1 ± 0.2°C); (iii) primarily core hyperthermia, with neutral Tskin (35.0 ± 0.5°C) and high Tcore (38.3 ± 0.2°C); and (iv) combined skin and core hyperthermia, with high Tskin (38.8 ± 0.6°C) and high Tcore (38.1 ± 0.2°C). The LBNP tolerance was quantified via the cumulative stress index (in millimetres of mercury × minutes). The LBNP tolerance was reduced during the skin

  8. The Earth's Inner Core: a Black Box

    Science.gov (United States)

    Tkalčić, Hrvoje

    2016-04-01

    that interact with the inner core boundary. iv) Recent studies have revealed complex structures in the lowermost mantle and outermost inner core that impose complex boundary conditions on the geodynamo. It is possible that the lowermost mantle structure is "mapped" onto the surface of the inner core through convection patterns in the outer core. There is much potential to make further progress on this topic due to the improving quality and increasing number of data and the continual advancements in mathematical geophysics, which can now provide uncertainty maps in addition to tomograms. v) The rotational dynamics of the inner core is still not well understood despite recent progress. While this topic is difficult to address seismologically due to the lack of the north-south ray-paths, the emergence of novel approaches to inverse problems and new seismological classes of data, such as interferometry datasets, is promising.

  9. Microstructural investigations on carbonate fault core rocks in active extensional fault zones from the central Apennines (Italy)

    Science.gov (United States)

    Cortinovis, Silvia; Balsamo, Fabrizio; Storti, Fabrizio

    2017-04-01

    The study of the microstructural and petrophysical evolution of cataclasites and gouges has a fundamental impact on both hydraulic and frictional properties of fault zones. In the last decades, growing attention has been payed to the characterization of carbonate fault core rocks due to the nucleation and propagation of coseismic ruptures in carbonate successions (e.g., Umbria-Marche 1997, L'Aquila 2009, Amatrice 2016 earthquakes in Central Apennines, Italy). Among several physical parameters, grain size and shape in fault core rocks are expected to control the way of sliding along the slip surfaces in active fault zones, thus influencing the propagation of coseismic ruptures during earthquakes. Nevertheless, the role of grain size and shape distribution evolution in controlling the weakening or strengthening behavior in seismogenic fault zones is still not fully understood also because a comprehensive database from natural fault cores is still missing. In this contribution, we present a preliminary study of seismogenic extensional fault zones in Central Apennines by combining detailed filed mapping with grain size and microstructural analysis of fault core rocks. Field mapping was aimed to describe the structural architecture of fault systems and the along-strike fault rock distribution and fracturing variations. In the laboratory we used a Malvern Mastersizer 3000 granulometer to obtain a precise grain size characterization of loose fault rocks combined with sieving for coarser size classes. In addition, we employed image analysis on thin sections to quantify the grain shape and size in cemented fault core rocks. The studied fault zones consist of an up to 5-10 m-thick fault core where most of slip is accommodated, surrounded by a tens-of-meters wide fractured damage zone. Fault core rocks consist of (1) loose to partially cemented breccias characterized by different grain size (from several cm up to mm) and variable grain shape (from very angular to sub

  10. GREEN CORE HOUSE

    Directory of Open Access Journals (Sweden)

    NECULAI Oana

    2017-05-01

    Full Text Available The Green Core House is a construction concept with low environmental impact, having as main central element a greenhouse. The greenhouse has the innovative role to use the biomass energy provided by plants to save energy. Although it is the central piece, the greenhouse is not the most innovative part of the Green Core House, but the whole building ensemble because it integrates many other sustainable systems as "waste purification systems", "transparent photovoltaic panels" or "double skin façades".

  11. Birefringent hollow core fibers

    DEFF Research Database (Denmark)

    Roberts, John

    2007-01-01

    Hollow core photonic crystal fiber (HC-PCF), fabricated according to a nominally non-birefringent design, shows a degree of un-controlled birefringence or polarization mode dispersion far in excess of conventional non polarization maintaining fibers. This can degrade the output pulse in many...... and an increased overlap between the polarization modes at the glass interfaces. The interplay between these effects leads to a wavelength for optimum polarization maintenance, lambda(PM), which is detuned from the wavelength of highest birefringence. By a suitable fiber design involving antiresonance of the core...

  12. Birefringent hollow core fibers

    DEFF Research Database (Denmark)

    Roberts, John

    2007-01-01

    Hollow core photonic crystal fiber (HC-PCF), fabricated according to a nominally non-birefringent design, shows a degree of un-controlled birefringence or polarization mode dispersion far in excess of conventional non polarization maintaining fibers. This can degrade the output pulse in many...... and an increased overlap between the polarization modes at the glass interfaces. The interplay between these effects leads to a wavelength for optimum polarization maintenance, lambda(PM), which is detuned from the wavelength of highest birefringence. By a suitable fiber design involving antiresonance of the core...

  13. EEA core set of indicators. Guide

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This guide provides information on the quality of the 37 indicators in the EEA core set. Its primary role is to support improved implementation of the core set in the EEA, European topic centres and the European environment information and observation network (Eionet). In parallel, it is aimed at helping users outside the EEA/Eionet system make best use of the indicators in their own work. It is hoped that the guide will promote cooperation on improving indicator methodologies and data quality as part of the wider process to streamline and improve environmental reporting in the European Union and beyond. (au)

  14. Essential ingredients in core-collapse supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Hix, W. Raphael [Physics Division, Oak Ridge National Laboratory, Oak Ridge TN 37831-6354 (United States); Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996-1200 (United States); Lentz, Eric J.; Chertkow, M. Austin; Harris, J. Austin [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996-1200 (United States); Endeve, Eirik [Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge TN 37831-6008 (United States); Baird, Mark [Reactor and Nuclear Systems Division, Oak Ridge National Laboratory, Oak Ridge TN 37831-6003 (United States); Messer, O. E. Bronson [Physics Division, Oak Ridge National Laboratory, Oak Ridge TN 37831-6354 (United States); Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996-1200 (United States); Center for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge TN 37831-6008 (United States); Mezzacappa, Anthony [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996-1200 (United States); Joint Institute for Computational Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6173 (United States); Bruenn, Stephen [Department of Physics, Florida Atlantic University, 777 W Glades Road, Boca Raton, FL 33431-0991 (United States); Blondin, John [Department of Physics, North Carolina State University, Raleigh, NC 27695-8202 (United States)

    2014-04-15

    Carrying 10{sup 44} joules of kinetic energy and a rich mix of newly synthesized atomic nuclei, core-collapse supernovae are the preeminent foundries of the nuclear species which make up our solar system and ourselves. Signaling the inevitable death of a massive star, and the birth of a neutron star or black hole, core-collapse supernovae combine physics over a wide range in spatial scales, from kilometer-sized hydrodynamic motions (eventually growing to gigameter scale) down to femtometer-scale nuclear reactions. We will discuss our emerging understanding of the convectively-unstable, neutrino-driven explosion mechanism, based on increasingly realistic neutrino radiation hydrodynamic simulations that include progressively better nuclear and particle physics. Multi-dimensional models with spectral neutrino transport from several research groups, which slowly develop successful explosions for a range of progenitors, have recently motivated changes in our understanding of the neutrino reheating mechanism. In a similar fashion, improvements in nuclear physics, most notably explorations of weak interactions on nuclei and the nuclear equation of state, continue to refine our understanding of the births of neutron stars and the supernovae that result. Recent progress on both the macroscopic and microscopic effects that affect core-collapse supernovae are discussed.

  15. Essential ingredients in core-collapse supernovae

    Directory of Open Access Journals (Sweden)

    W. Raphael Hix

    2014-03-01

    Full Text Available Carrying 1044 joules of kinetic energy and a rich mix of newly synthesized atomic nuclei, core-collapse supernovae are the preeminent foundries of the nuclear species which make up our solar system and ourselves. Signaling the inevitable death of a massive star, and the birth of a neutron star or black hole, core-collapse supernovae combine physics over a wide range in spatial scales, from kilometer-sized hydrodynamic motions (eventually growing to gigameter scale down to femtometer-scale nuclear reactions. We will discuss our emerging understanding of the convectively-unstable, neutrino-driven explosion mechanism, based on increasingly realistic neutrino radiation hydrodynamic simulations that include progressively better nuclear and particle physics. Multi-dimensional models with spectral neutrino transport from several research groups, which slowly develop successful explosions for a range of progenitors, have recently motivated changes in our understanding of the neutrino reheating mechanism. In a similar fashion, improvements in nuclear physics, most notably explorations of weak interactions on nuclei and the nuclear equation of state, continue to refine our understanding of the births of neutron stars and the supernovae that result. Recent progress on both the macroscopic and microscopic effects that affect core-collapse supernovae are discussed.

  16. Engineering strategies aimed at control of acidification rate of lactic acid bacteria

    DEFF Research Database (Denmark)

    Martinussen, Jan; Solem, Christian; Holm, Anders Koefoed

    2013-01-01

    The ability of lactic acid bacteria to produce lactic acid from various sugars plays an important role in food fermentations. Lactic acid is derived from pyruvate, the end product of glycolysis and thus a fast lactic acid production rate requires a high glycolytic flux. In addition to lactic acid......, alternative end products - ethanol, acetic acid and formic acid - are formed by many species. The central role of glycolysis in lactic acid bacteria has provoked numerous studies aiming at identifying potential bottleneck(s) since knowledge about flux control could be important not only for optimizing food...... fermentation processes, but also for novel applications of lactic acid bacteria, such as cell factories for the production of green fuels and chemicals. With respect to the control and regulation of the fermentation mode, some progress has been made, but the question of which component(s) control the main...

  17. [Eugenics: progress or backward movement?].

    Science.gov (United States)

    González de Cancino, Emilssen

    2007-01-01

    Throughout this article there is a critical analysis of how genetics presents a dilemma for "human progress". So much so, that the legal world aims to create unequivocal norms and guarantees in relation with eugenics in order to avoid attempting against human dignity. The document makes the reader reflect on the ethical problems that eugenics can entail.

  18. Aiming Control.

    Science.gov (United States)

    1987-10-01

    positive definite solution of A1Qy+QyAo+I--QyBBTQY=O (5.2) The logarithmic residence time of system (3.1) with the stabilizing control (5.1) in a I...a bounded is E bou,,,,dby, ii I)-2=(6 2 This completes the prooof the necesity. Suffidency: The proof is by conatnction. Select a stabilizing control u...a - . Q.LD. Proof of Theorem 3.3: It follows from the results of [151, [21] that for each y > 0, K? defined by (3.4) is a stabilizing control and

  19. EDITORIAL: Catalysing progress Catalysing progress

    Science.gov (United States)

    Demming, Anna

    2010-01-01

    Examples of the merits of blue-sky research in the history of science are legion. The invention of the laser, celebrating its 50th anniversary this year, is an excellent example. When it was invented it was considered to be 'a solution waiting for a problem', and yet the level to which it has now infiltrated our day-to-day technological landscape speaks volumes. At the same time it is also true to say that the direction of research is also at times rightly influenced by the needs and concerns of the general public. Over recent years, growing concerns about the environment have had a noticeable effect on research in nanotechnology, motivating work on a range of topics from green nanomaterial synthesis [1] to high-efficiency solar cells [2] and hydrogen storage [3]. The impact of the world's energy consumption on the welfare of the planet is now an enduring and well founded concern. In the face of an instinctive reluctance to curtail habits of comfort and convenience and the appendages of culture and consumerism, research into renewable and more efficient energy sources seem an encouraging approach to alleviating an impending energy crisis. Fuel cells present one alternative to traditional combustion cells that have huge benefits in terms of the efficiency of energy conversion and the limited harmful emissions. In last week's issue of Nanotechnology, Chuan-Jian Zhong and colleagues at the State University of New York at Binghamton in the USA presented an overview of research on nanostructured catalysts in fuel cells [4]. The topical review includes insights into the interactions between nanoparticles and between nanoparticles and their substrate as well as control over the composition and nanostructure of catalysts. The review also serves to highlight how the flourishing of nanotechnology research has heralded great progress in the exploitation of catalysts with nanostructures ingeniously controlled to maximize surface area and optimize energetics for synthesis

  20. Investigation of EAS cores

    Science.gov (United States)

    Shaulov, S. B.; Beyl, P. F.; Beysembaev, R. U.; Beysembaeva, E. A.; Bezshapov, S. P.; Borisov, A. S.; Cherdyntceva, K. V.; Chernyavsky, M. M.; Chubenko, A. P.; Dalkarov, O. D.; Denisova, V. G.; Erlykin, A. D.; Kabanova, N. V.; Kanevskaya, E. A.; Kotelnikov, K. A.; Morozov, A. E.; Mukhamedshin, R. A.; Nam, R. A.; Nesterova, N. M.; Nikolskaya, N. M.; Pavluchenko, V. P.; Piskal, V. V.; Puchkov, V. S.; Pyatovsky, S. E.; Ryabov, V. A.; Sadykov, T. Kh.; Schepetov, A. L.; Smirnova, M. D.; Stepanov, A. V.; Uryson, A. V.; Vavilov, Yu. N.; Vildanov, N. G.; Vildanova, L. I.; Zayarnaya, I. S.; Zhanceitova, J. K.; Zhukov, V. V.

    2017-06-01

    The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS). These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC) as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons) in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015-1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum `knee' range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  1. Some Core Contested Concepts

    Science.gov (United States)

    Chomsky, Noam

    2015-01-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and…

  2. Looking for Core Values

    Science.gov (United States)

    Carter, Margie

    2010-01-01

    People who view themselves as leaders, not just managers or teachers, are innovators who focus on clarifying core values and aligning all aspects of the organization with these values to grow their vision. A vision for an organization can't be just one person's idea. Visions grow by involving people in activities that help them name and create…

  3. Nucleosome Core Particle

    Science.gov (United States)

    1997-01-01

    Nucleosome Core Particle grown on STS-81. The fundamental structural unit of chromatin and is the basis for organization within the genome by compaction of DNA within the nucleus of the cell and by making selected regions of chromosomes available for transcription and replication. Principal Investigator's are Dr. Dan Carter and Dr. Gerard Bunick of New Century Pharmaceuticals.

  4. Investigation of EAS cores

    Directory of Open Access Journals (Sweden)

    Shaulov S.B.

    2017-01-01

    Full Text Available The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS. These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015–1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum ‘knee’ range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  5. The Earth's Core.

    Science.gov (United States)

    Jeanloz, Raymond

    1983-01-01

    The nature of the earth's core is described. Indirect evidence (such as that determined from seismological data) indicates that it is an iron alloy, solid toward its center but otherwise liquid. Evidence also suggests that it is the turbulent flow of the liquid that generates the earth's magnetic field. (JN)

  6. Some Core Contested Concepts

    Science.gov (United States)

    Chomsky, Noam

    2015-01-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and…

  7. Languages for Dublin Core.

    Science.gov (United States)

    Baker, Thomas

    1998-01-01

    Focusing on languages for the Dublin Core, examines the experience of some related ways to seek semantic interoperability through simplicity: planned languages, interlingua constructs, and pidgins. Also defines the conceptual and organizational problem of maintaining a metadata standard in multiple languages. (AEF)

  8. Core calculations of JMTR

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Yoshiharu [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    1998-03-01

    In material testing reactors like the JMTR (Japan Material Testing Reactor) of 50 MW in Japan Atomic Energy Research Institute, the neutron flux and neutron energy spectra of irradiated samples show complex distributions. It is necessary to assess the neutron flux and neutron energy spectra of an irradiation field by carrying out the nuclear calculation of the core for every operation cycle. In order to advance core calculation, in the JMTR, the application of MCNP to the assessment of core reactivity and neutron flux and spectra has been investigated. In this study, in order to reduce the time for calculation and variance, the comparison of the results of the calculations by the use of K code and fixed source and the use of Weight Window were investigated. As to the calculation method, the modeling of the total JMTR core, the conditions for calculation and the adopted variance reduction technique are explained. The results of calculation are shown. Significant difference was not observed in the results of neutron flux calculations according to the difference of the modeling of fuel region in the calculations by K code and fixed source. The method of assessing the results of neutron flux calculation is described. (K.I.)

  9. The core and cosmopolitans

    DEFF Research Database (Denmark)

    Dahlander, Linus; Frederiksen, Lars

    2012-01-01

    Users often interact and help each other solve problems in communities, but few scholars have explored how these relationships provide opportunities to innovate. We analyze the extent to which people positioned within the core of a community as well as people that are cosmopolitans positioned...

  10. Schumpeter's core works revisited

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    2012-01-01

    This paper organises Schumpeter’s core books in three groups: the programmatic duology,the evolutionaryeconomic duology,and the socioeconomic synthesis. By analysing these groups and their interconnections from the viewpoint of modern evolutionaryeconomics,the paper summarises resolved problems...

  11. Adult educators' core competences

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne

    2016-01-01

    environment as well as the kind of adult education concerned (e.g. basic education, work-related education etc.). However, it seems that it is possible to identify certain competence requirements which transcend national, cultural and functional boundaries. This research note summarises these common or “core...

  12. Adult educators' core competences

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne

    2016-01-01

    environment as well as the kind of adult education concerned (e.g. basic education, work-related education etc.). However, it seems that it is possible to identify certain competence requirements which transcend national, cultural and functional boundaries. This research note summarises these common or “core...

  13. The DLESE Evaluation Core Services Project

    Science.gov (United States)

    Buhr, S. M.; Barker, L. J.; Reeves, T. C.

    2003-12-01

    The DLESE Evaluation Core Service project will conduct evaluation of DLESE and provide evaluation consultation, resources and services to the DLESE community. Through this work we anticipate that we will learn more about the impact and use of digital libraries, and will promote an evaluation mindset within the geoscience education community. Activities of the DLESE Evaluation Service team include 1) evaluation planning for and of DLESE, 2) conducting formative evaluation of DLESE (user needs, data access, collections, outreach), 3) conducting classroom evaluation of DLESE use on teaching practices and learning outcomes, and 4) collection, synthesis, and reporting of evaluation findings garnered from all core teams and major projects. Many opportunities for community involvement exist. A strand group convened during the 2004 DLESE Annual Meeting took DLESE Evaluation as their topic, provided recommendations and will continue their activities through the year. The related Evaluation Toolkit collection is now discoverable through DLESE, and upcoming activities of all the core teams will provide evaluation opportunities to be described. Other community opportunities include consulting with Evaluation Service for education grant proposals, attending an evaluation workshop,and applying for an Evaluation Minigrant (up to \\$5K per award) Progress to date will be discussed, the Evaluation Core Services team members will be introduced, and plans and opportunities will be described in more detail.

  14. From DeepCore to PINGU

    Directory of Open Access Journals (Sweden)

    Yáñez J.P.

    2016-01-01

    Full Text Available Very large volume neutrino telescopes (VLVNTs observe atmospheric neutrinos over a wide energy range (GeV to TeV, after they travel distances as large as the Earth's diameter. DeepCore, the low energy extension of IceCube, has started making meaningful measurements of the neutrino oscillation parameters θ23 and | Δm232| by analyzing the atmospheric flux at energies above 10 GeV. PINGU, a proposed project to lower DeepCore's energy threshold, aims to use the same flux to further increase the precision with which these parameters are known, and eventually determine the sign of Δm232. The latest results from DeepCore, and the planned transition to PINGU, are discussed here.

  15. Core Competencies for Injury and Violence Prevention

    Science.gov (United States)

    Stephens-Stidham, Shelli; Peek-Asa, Corinne; Bou-Saada, Ingrid; Hunter, Wanda; Lindemer, Kristen; Runyan, Carol

    2009-01-01

    Efforts to reduce the burden of injury and violence require a workforce that is knowledgeable and skilled in prevention. However, there has been no systematic process to ensure that professionals possess the necessary competencies. To address this deficiency, we developed a set of core competencies for public health practitioners in injury and violence prevention programs. The core competencies address domains including public health significance, data, the design and implementation of prevention activities, evaluation, program management, communication, stimulating change, and continuing education. Specific learning objectives establish goals for training in each domain. The competencies assist in efforts to reduce the burden of injury and violence and can provide benchmarks against which to assess progress in professional capacity for injury and violence prevention. PMID:19197083

  16. Progressive Education in Georgia: Tradition or Reality?

    Science.gov (United States)

    Kopaliani, Bella; Harnisch, Delwyn L.; Doliashvili, Nana; Guetterman, Timothy C.

    2013-01-01

    Despite differences among progressive educators, they share the conviction that democracy means active participation by all citizens in the social, political, and economic decisions of their countries. The aim of this paper is to explore how Georgia is meeting goals and perspectives of progressive education by widely implementing civic education…

  17. USGS Core Research Center (CRC) Collection of Core

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Core Research Center (CRC) was established in 1974 by the U.S. Geological Survey (USGS) to preserve valuable rock cores for use by scientists and educators from...

  18. Ice Cores of the National Ice Core Laboratory

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The U.S. National Ice Core Laboratory (NICL) is a facility for storing, curating, and studying ice cores recovered from the polar regions of the world. It provides...

  19. Liver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transition.

    Directory of Open Access Journals (Sweden)

    Serena Battaglia

    Full Text Available BACKGROUND: Chronic hepatitis C virus (HCV infection and associated liver cirrhosis represent a major risk factor for hepatocellular carcinoma (HCC development. TGF-beta is an important driver of liver fibrogenesis and cancer; however, its actual impact in human cancer progression is still poorly known. The aim of this study was to investigate the role of HCC-derived HCV core natural variants on cancer progression through their impact on TGF-beta signaling. PRINCIPAL FINDINGS: We provide evidence that HCC-derived core protein expression in primary human or mouse hepatocyte alleviates TGF-beta responses in terms or growth inhibition or apoptosis. Instead, in these hepatocytes TGF-beta was still able to induce an epithelial to mesenchymal transition (EMT, a process that contributes to the promotion of cell invasion and metastasis. Moreover, we demonstrate that different thresholds of Smad3 activation dictate the TGF-beta responses in hepatic cells and that HCV core protein, by decreasing Smad3 activation, may switch TGF-beta growth inhibitory effects to tumor promoting responses. CONCLUSION/SIGNIFICANCE: Our data illustrate the capacity of hepatocytes to develop EMT and plasticity under TGF-beta, emphasize the role of HCV core protein in the dynamic of these effects and provide evidence for a paradigm whereby a viral protein implicated in oncogenesis is capable to shift TGF-beta responses from cytostatic effects to EMT development.

  20. Core Outlet Temperature Study

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, A. [Argonne National Laboratory (ANL), Argonne, IL (United States); Hoffman, E. [Argonne National Laboratory (ANL), Argonne, IL (United States); Majumdar, S. [Argonne National Laboratory (ANL), Argonne, IL (United States)

    2008-07-28

    It is a known fact that the power conversion plant efficiency increases with elevation of the heat addition temperature. The higher efficiency means better utilization of the available resources such that higher output in terms of electricity production can be achieved for the same size and power of the reactor core or, alternatively, a lower power core could be used to produce the same electrical output. Since any nuclear power plant, such as the Advanced Burner Reactor, is ultimately built to produce electricity, a higher electrical output is always desirable. However, the benefits of the higher efficiency and electricity production usually come at a price. Both the benefits and the disadvantages of higher reactor outlet temperatures are analyzed in this work.

  1. Geomagnetism of earth's core

    Science.gov (United States)

    Benton, E. R.

    1983-01-01

    Instrumentation, analytical methods, and research goals for understanding the behavior and source of geophysical magnetism are reviewed. Magsat, launched in 1979, collected global magnetometer data and identified the main terrestrial magnetic fields. The data has been treated by representing the curl-free field in terms of a scalar potential which is decomposed into a truncated series of spherical harmonics. Solutions to the Laplace equation then extend the field upward or downward from the measurement level through intervening spaces with no source. Further research is necessary on the interaction between harmonics of various spatial scales. Attempts are also being made to analytically model the main field and its secular variation at the core-mantle boundary. Work is also being done on characterizing the core structure, composition, thermodynamics, energetics, and formation, as well as designing a new Magsat or a tethered satellite to be flown on the Shuttle.

  2. Geomagnetism of earth's core

    Science.gov (United States)

    Benton, E. R.

    1983-01-01

    Instrumentation, analytical methods, and research goals for understanding the behavior and source of geophysical magnetism are reviewed. Magsat, launched in 1979, collected global magnetometer data and identified the main terrestrial magnetic fields. The data has been treated by representing the curl-free field in terms of a scalar potential which is decomposed into a truncated series of spherical harmonics. Solutions to the Laplace equation then extend the field upward or downward from the measurement level through intervening spaces with no source. Further research is necessary on the interaction between harmonics of various spatial scales. Attempts are also being made to analytically model the main field and its secular variation at the core-mantle boundary. Work is also being done on characterizing the core structure, composition, thermodynamics, energetics, and formation, as well as designing a new Magsat or a tethered satellite to be flown on the Shuttle.

  3. Dynamics of core accretion

    Science.gov (United States)

    Nelson, Andrew F.; Ruffert, Maximilian

    2013-02-01

    We perform three-dimensional hydrodynamic simulations of gas flowing around a planetary core of mass Mpl = 10M⊕ embedded in a near Keplerian background flow, using a modified shearing box approximation. We assume an ideal gas behaviour following an equation of state with a fixed ratio of the specific heats, γ = 1.42, consistent with the conditions of a moderate-temperature background disc with solar composition. No radiative heating or cooling is included in the models. We employ a nested grid hydrodynamic code implementing the `Piecewise Parabolic Method' with as many as six fixed nested grids, providing spatial resolution on the finest grid comparable to the present-day diameters of Neptune and Uranus. We find that a strongly dynamically active flow develops such that no static envelope can form. The activity is not sensitive to plausible variations in the rotation curve of the underlying disc. It is sensitive to the thermodynamic treatment of the gas, as modelled by prescribed equations of state (either `locally isothermal' or `locally isentropic') and the temperature of the background disc material. The activity is also sensitive to the shape and depth of the core's gravitational potential, through its mass and gravitational softening coefficient. Each of these factors influences the magnitude and character of hydrodynamic feedback of the small-scale flow on the background, and we conclude that accurate modelling of such feedback is critical to a complete understanding of the core accretion process. The varying flow pattern gives rise to large, irregular eruptions of matter from the region around the core which return matter to the background flow: mass in the envelope at one time may not be found in the envelope at any later time. No net mass accretion into the envelope is observed over the course of the simulation and none is expected, due to our neglect of cooling. Except in cases of very rapid cooling however, as defined by locally isothermal or

  4. (Extreme) Core-collapse Supernova Simulations

    Science.gov (United States)

    Mösta, Philipp

    2017-01-01

    In this talk I will present recent progress on modeling core-collapse supernovae with massively parallel simulations on the largest supercomputers available. I will discuss the unique challenges in both input physics and computational modeling that come with a problem involving all four fundamental forces and relativistic effects and will highlight recent breakthroughs overcoming these challenges in full 3D simulations. I will pay particular attention to how these simulations can be used to reveal the engines driving some of the most extreme explosions and conclude by discussing what remains to be done in simulation work to maximize what we can learn from current and future time-domain astronomy transient surveys.

  5. Core Elements of Outpatient Antibiotic Stewardship.

    Science.gov (United States)

    Sanchez, Guillermo V; Fleming-Dutra, Katherine E; Roberts, Rebecca M; Hicks, Lauri A

    2016-11-11

    The Core Elements of Outpatient Antibiotic Stewardship provides a framework for antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic treatment. This report augments existing guidance for other clinical settings. In 2014 and 2015, respectively, CDC released the Core Elements of Hospital Antibiotic Stewardship Programs and the Core Elements of Antibiotic Stewardship for Nursing Homes. Antibiotic stewardship is the effort to measure and improve how antibiotics are prescribed by clinicians and used by patients. Improving antibiotic prescribing involves implementing effective strategies to modify prescribing practices to align them with evidence-based recommendations for diagnosis and management. The four core elements of outpatient antibiotic stewardship are commitment, action for policy and practice, tracking and reporting, and education and expertise. Outpatient clinicians and facility leaders can commit to improving antibiotic prescribing and take action by implementing at least one policy or practice aimed at improving antibiotic prescribing practices. Clinicians and leaders of outpatient clinics and health care systems can track antibiotic prescribing practices and regularly report these data back to clinicians. Clinicians can provide educational resources to patients and families on appropriate antibiotic use. Finally, leaders of outpatient clinics and health systems can provide clinicians with education aimed at improving antibiotic prescribing and with access to persons with expertise in antibiotic stewardship. Establishing effective antibiotic stewardship interventions can protect patients and improve clinical outcomes in outpatient health care settings.

  6. Some core contested concepts.

    Science.gov (United States)

    Chomsky, Noam

    2015-02-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and to lead to conclusions about a number of significant issues that differ from some conventional beliefs.

  7. Massive Computation for Understanding Core-Collapse Supernova Explosions

    CERN Document Server

    Ott, Christian D

    2016-01-01

    How do massive stars explode? Progress toward the answer is driven by increases in compute power. Petascale supercomputers are enabling detailed three-dimensional simulations of core-collapse supernovae. These are elucidating the role of fluid instabilities, turbulence, and magnetic field amplification in supernova engines.

  8. Multi-core and/or symbolic model checking

    NARCIS (Netherlands)

    Dijk, van Tom; Laarman, Alfons; Pol, van de Jaco; Luettgen, G.; Merz, S.

    2012-01-01

    We review our progress in high-performance model checking. Our multi-core model checker is based on a scalable hash-table design and parallel random-walk traversal. Our symbolic model checker is based on Multiway Decision Diagrams and the saturation strategy. The LTSmin tool is based on the PINS arc

  9. Core-seis: a code for LMFBR core seismic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chellapandi, P.; Ravi, R.; Chetal, S.C.; Bhoje, S.B. [Indira Gandhi Centre for Atomic Research, Kalpakkam (India). Reactor Group

    1995-12-31

    This paper deals with a computer code CORE-SEIS specially developed for seismic analysis of LMFBR core configurations. For demonstrating the prediction capability of the code, results are presented for one of the MONJU reactor core mock ups which deals with a cluster of 37 subassemblies kept in water. (author). 3 refs., 7 figs., 2 tabs.

  10. Core Exercises: Why You Should Strengthen Your Core Muscles

    Science.gov (United States)

    Healthy Lifestyle Fitness You know core exercises are good for you — but do you include core exercises in your fitness routine? Here's why ... 18, 2014 Original article: http://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/core-exercises/art-20044751 . Mayo Clinic Footer Legal Conditions and ...

  11. Learning numerical progressions.

    Science.gov (United States)

    Vitz, P C; Hazan, D N

    1974-01-01

    Learning of simple numerical progressions and compound progressions formed by combining two or three simple progressions is investigated. In two experiments, time to solution was greater for compound vs simple progressions; greater the higher the progression's solution level; and greater if the progression consisted of large vs small numbers. A set of strategies is proposed to account for progression learning based on the assumption S computes differences between integers, differences between differences, etc., in a hierarchical fashion. Two measures of progression difficulty, each a summary of the strategies, are proposed; C1 is a count of the number of differences needed to solve a progression; C2 is the same count with higher level differences given more weight. The measures accurately predict in both experiments the mean time to solve 16 different progressions with C2 being somewhat superior. The measures also predict the learning difficulty of 10 other progressions reported by Bjork (1968).

  12. ICF Core Sets for stroke

    National Research Council Canada - National Science Library

    Szilvia Geyh; Alarcos Cieza; Jan Schouten; Hugh Dickson; Peter Frommelt; Zaliha Omar; Nenad Kostanjsek; Haim Ring; Gerold Stucki

    2004-01-01

    Objective: To report on the results of the consensus process integrating evidence from preliminary studies to develop the first version of the Comprehensive ICF Core Set and the Brief ICF Core Set for stroke. Methods...

  13. BRIF and CARIF progress

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    China Institute of Atomic Energy (CIAE) is currently constructing Beijing rare ion beam facility (BRIF) and is proposing China advanced rare ion beam facility (CARIF). This paper is aiming at introducing the progress of BRIF project and the con ceptual design CARIF. The ISOL type facility BRIF under construction is composed of a 100 MeV 300 ?A proton cyclotron, an ISOL with mass resolution of 20000, and a super-conducting LINAC of 2 MeV/q, and will be commissioned in 2013. CARIF facility proposed is planned to use both ISOL and PF techniques. It is based on a China advanced research reactor CARR that was critical, with ISOL separation of fission fragment, post acceleration to 150 MeV/u, and fragmentation of neu tron-rich fission fragment beam like 132Sn. Such unique combination will allow CARIF to deliver beam intensity better than the best world facilities by more than one order of magnitude.

  14. BNL program in support of LWR degraded-core accident analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ginsberg, T.; Greene, G.A.

    1982-01-01

    Two major sources of loading on dry watr reactor containments are steam generatin from core debris water thermal interactions and molten core-concrete interactions. Experiments are in progress at BNL in support of analytical model development related to aspects of the above containment loading mechanisms. The work supports development and evaluation of the CORCON (Muir, 1981) and MARCH (Wooton, 1980) computer codes. Progress in the two programs is described in this paper. 8 figures.

  15. Hollow-Core Fiber Lamp

    Science.gov (United States)

    Yi, Lin (Inventor); Tjoelker, Robert L. (Inventor); Burt, Eric A. (Inventor); Huang, Shouhua (Inventor)

    2016-01-01

    Hollow-core capillary discharge lamps on the millimeter or sub-millimeter scale are provided. The hollow-core capillary discharge lamps achieve an increased light intensity ratio between 194 millimeters (useful) and 254 millimeters (useless) light than conventional lamps. The capillary discharge lamps may include a cone to increase light output. Hollow-core photonic crystal fiber (HCPCF) may also be used.

  16. On core stability and extendability

    OpenAIRE

    Shellshear, Evan

    2007-01-01

    This paper investigates conditions under which the core of a TU cooperative game is stable. In particular the author extends the idea of extendability to find new conditions under which the core is stable. It is also shown that these new conditions are not necessary for core stability.

  17. Dual-core Itanium Processor

    CERN Multimedia

    2006-01-01

    Intel’s first dual-core Itanium processor, code-named "Montecito" is a major release of Intel's Itanium 2 Processor Family, which implements the Intel Itanium architecture on a dual-core processor with two cores per die (integrated circuit). Itanium 2 is much more powerful than its predecessor. It has lower power consumption and thermal dissipation.

  18. On core stability and extendability

    OpenAIRE

    Shellshear, Evan

    2007-01-01

    This paper investigates conditions under which the core of a TU cooperative game is stable. In particular the author extends the idea of extendability to find new conditions under which the core is stable. It is also shown that these new conditions are not necessary for core stability.

  19. Core to College Evaluation: Statewide Networks. Connecting Education Systems and Stakeholders to Support College Readiness

    Science.gov (United States)

    Bracco, Kathy Reeves; Klarin, Becca; Broek, Marie; Austin, Kim; Finkelstein, Neal; Bugler, Daniel; Mundry, Susan

    2014-01-01

    The Core to College initiative aims to facilitate greater coordination between K-12 and postsecondary education systems around implementation of the Common Core State Standards and aligned assessments. Core to College grants have been awarded to teams in Colorado, Florida, Hawaii, Kentucky, Louisiana, Massachusetts, North Carolina, Oregon,…

  20. The Danish national return-to-work program--aims, content, and design of the process and effect evaluation

    DEFF Research Database (Denmark)

    Aust, Birgit; Helverskov, Trine; Nielsen, Maj Britt D

    2012-01-01

    The Danish national return-to-work (RTW) program aims to improve the management of municipal sickness benefit in Denmark. A study is currently ongoing to evaluate the RTW program. The purpose of this article is to describe the study protocol. The program includes 21 municipalities encompassing...... approximately 19 500 working-age adults on long-term sickness absence, regardless of reason for sickness absence or employment status. It consists of three core elements: (i) establishment of multidisciplinary RTW teams, (ii) introduction of standardized workability assessments and sickness absence management...

  1. The study of core melting phenomena in reactor severe accident of PWR

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae Hong; Jeun, Gyoo Dong; Park, Seh In; Lim, Jae Hyuck; Park, Seong Yong [Hanyang Univ., Seoul (Korea, Republic of); Bang, Kwang Hyun; Kim, Ki Yong [Korea Maritime Univ., Busan (Korea, Republic of)

    1999-03-15

    After TMI-2 accident, it has been paid much attention to severe accidents beyond the design basis accidents and the research on the progress of severe accidents and mitigation and the closure of severe accidents has been actively performed. In particular, a great deal of uncertainties yet exist in the phase of late core melt progression and thus the research on this phase of severe accident progress has a key role in obtaining confidence in severe accident mitigation and nuclear reactor safety. In the present study, physics of late core melt progression, experimental data and the major phenomenological models of computer codes are reviewed and a direction of reducing the uncertainties in the late core melt progression is proposed.

  2. The study of core melting phenomena in reactor severe accident of PWR

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jae Hong; Jeun, Gyoo Dong; Park, Seh In; Lim, Jae Hyuck; Park, Seong Yong [Hanyang Univ., Seoul (Korea, Republic of); Bang, Kwang Hyun; Kim, Ki Yong [Korea Maritime Univ., Busan (Korea, Republic of)

    1999-03-15

    After TMI-2 accident, it has been paid much attention to severe accidents beyond the design basis accidents and the research on the progress of severe accidents and mitigation and the closure of severe accidents has been actively performed. In particular, a great deal of uncertainties yet exist in the phase of late core melt progression and thus the research on this phase of severe accident progress has a key role in obtaining confidence in severe accident mitigation and nuclear reactor safety. In the present study, physics of late core melt progression, experimental data and the major phenomenological models of computer codes are reviewed and a direction of reducing the uncertainties in the late core melt progression is proposed.

  3. What Can the Common Core State Standards Initiative Learn from the National Assessment Governing Board?

    Science.gov (United States)

    Musick, Mark

    2010-01-01

    The Common Core State Standards Initiative (CCSSI) is a bit like the underdog candidate who wins the election when few think it possible. "Now what?" is the question facing the surprised victor. With an initial agreement for the Common Core State Standards to be developed, and visible progress toward their development and promulgation, what will…

  4. Geothermal progress monitor. Progress report No. 1

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-01

    Progress is reported on the following: electrical uses, direct-heat uses, drilling activities, leases, geothermal loan guarantee program, general activities, and legal, institutional, and regulatory activites. (MHR)

  5. Winning Cores in Parity Games

    DEFF Research Database (Denmark)

    Vester, Steen

    2016-01-01

    We introduce the novel notion of winning cores in parity games and develop a deterministic polynomial-time under-approximation algorithm for solving parity games based on winning core approximation. Underlying this algorithm are a number properties about winning cores which are interesting...... in their own right. In particular, we show that the winning core and the winning region for a player in a parity game are equivalently empty. Moreover, the winning core contains all fatal attractors but is not necessarily a dominion itself. Experimental results are very positive both with respect to quality...

  6. SBIR Final Report. Liquid Core Optical Scintillating Fibers

    Energy Technology Data Exchange (ETDEWEB)

    Beetz, C.P.; Steinbeck, J.; Buerstler, R.

    2000-05-16

    This Phase I SBIR project focused on developing flexible scintillating liquid core optical fibers, with potential uses in high-energy calorimetry, tracking, preradiators, active targets or other fast detectors. Progress on the six tasks of the project is summarized. The technical developments involve three technology components: (1) highly flexible capillaries or tubes of relatively low n (index of refraction) to serve as cladding and liquid core containment; (2) scintillator (and clear) fluids of relatively high n to serve as a core-- these fluids must have a high light transmission and, for some applications, radiation hardness; (3) optical end plugs, plug insertion, and plug-cladding tube sealing technology to contain the core fluids in the tubes, and to transmit the light.

  7. Models of the earth's core

    Science.gov (United States)

    Stevenson, D. J.

    1981-01-01

    Combined inferences from seismology, high-pressure experiment and theory, geomagnetism, fluid dynamics, and current views of terrestrial planetary evolution lead to models of the earth's core with five basic properties. These are that core formation was contemporaneous with earth accretion; the core is not in chemical equilibrium with the mantle; the outer core is a fluid iron alloy containing significant quantities of lighter elements and is probably almost adiabatic and compositionally uniform; the more iron-rich inner solid core is a consequence of partial freezing of the outer core, and the energy release from this process sustains the earth's magnetic field; and the thermodynamic properties of the core are well constrained by the application of liquid-state theory to seismic and labroatory data.

  8. Physical properties of dense cores in Orion B9

    CERN Document Server

    Miettinen, Oskari; Haikala, Lauri K; Juvela, Mika

    2010-01-01

    We aim to determine the physical and chemical properties of dense cores in Orion B9. We observed the NH3(1,1) and (2,2), and the N2H+(3-2) lines towards the submm peak positions. These data are used in conjunction with our LABOCA 870 micron dust continuum data. The gas kinetic temperature in the cores is between ~9.4-13.9 K. The non-thermal velocity dispersion is subsonic in most of the cores. The non-thermal linewidth in protostellar cores appears to increase with increasing bolometric luminosity. The core masses are very likely drawn from the same parent distribution as the core masses in Orion B North. Starless cores in the region are likely to be gravitationally bound, and thus prestellar. Some of the cores have a lower radial velocity than the systemic velocity of the region, suggesting that they are members of the "low-velocity part" of Orion B. The observed core-separation distances deviate from the corresponding random-like model distributions. The distances between the nearest-neighbours are comparab...

  9. THE AIMS AND ACTIVITIES OF THE INTERNATIONAL NETWORK OF NUCLEAR STRUCTURE AND DECAY DATA EVALUATORS.

    Energy Technology Data Exchange (ETDEWEB)

    NICHOLS,A.L.; TULI, J.K.

    2007-04-22

    International Network of Nuclear Structure and Decay Data (NSDD) Evaluators consists of a number of evaluation groups and data service centers in several countries that appreciate the merits of working together to maintain and ensure the quality and comprehensive content of the ENSDF database (Evaluated Nuclear Structure Data File). Biennial meetings of the network are held under the auspices of the International Atomic Energy Agency (IAEA) to assign evaluation responsibilities, monitor progress, discuss improvements and emerging difficulties, and agree on actions to be undertaken by individual members. The evaluated data and bibliographic details are made available to users via various media, such as the journals ''Nuclear Physics A'' and ''Nuclear Data Sheets'', the World Wide Web, on CD-ROM, wall charts of the nuclides and ''Nuclear Wallet Cards''. While the ENSDF master database is maintained by the US National Nuclear Data Center at the Brookhaven National Laboratory, these data are also available from other nuclear data centers including the IAEA Nuclear Data Section. The Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy, in cooperation with the IAEA, organizes workshops on NSDD at regular intervals. The primary aims of these particular workshops are to provide hands-on training in the data evaluation processes, and to encourage new evaluators to participate in NSDD activities. The technical contents of these NSDD workshops are described, along with the rationale for the inclusion of various topics.

  10. 1997 Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Cecchini, M.; Crescentini, L.; Ghezzi, L. [ENEA, Centro Ricerche Frascati, Rome (Italy). Nuclear fusion division

    1997-12-31

    1997 was another year of intense activity for the ENEA Nuclear Fusion Division in the evolving scenario of fusion research. With respect to the International Thermonuclear Experimental Reactor (ITER), a major review process has started, originate by the wide perception that the difficult financial situation affecting some of the parties would make it very difficult, practically impossible, to secure funding for the project as it stands. To scale down the size and cost of the machine by reducing the technical objectives, while keeping to the programmatic goal of constructing a demonstration reactor (DEMO) as the following step, appears achievable. Progress in physics was substantial during 1997. Analysis of the huge existing database, complemented by the latest results, had led to a better, more accurate scaling for the confinement time on which to base extrapolation to ITER. Studies of the very promising advanced regimes have been pursued on many tokamaks. The Frascati Tokamak Upgrade (FTU) is well placed in this respect since it is equipped with the right tools, lower hybrid and electron cyclotron radiofrequency heating and current drive systems, to explore the new promised land of low transport from the plasma core. The main highlights of FTU operation in 1997 were related to providing information relevant to these future developments. Transient production of low transport regimes with electron temperatures of 8-9 keV at the plasma center was obtained by taking advantage of the plasma skin effect and precise electron cyclotron power deposition. High-efficiency current drive at high density using lower hybrid waves was demonstrated. High-confinement pellet-enhanced modes of operation and good ion Bernstein wave coupling through the waveguide-type coupler were also achieved. Concerning the IGNITOR experiment, funds were made available only for continuation of the engineering design activities, and nothing has been released so far for manufacturing the additional

  11. Development and Integration of Professional Core Values Among Practicing Clinicians.

    Science.gov (United States)

    McGinnis, Patricia Quinn; Guenther, Lee Ann; Wainwright, Susan F

    2016-09-01

    The physical therapy profession has adopted professional core values, which define expected values for its members, and developed a self-assessment tool with sample behaviors for each of the 7 core values. However, evidence related to the integration of these core values into practice is limited. The aims of this study were: (1) to gain insight into physical therapists' development of professional core values and (2) to gain insight into participants' integration of professional core values into clinical practice. A qualitative design permitted in-depth exploration of the development and integration of the American Physical Therapy Association's professional core values into physical therapist practice. Twenty practicing physical therapists were purposefully selected to explore the role of varied professional, postprofessional, and continuing education experiences related to exposure to professional values. The Core Values Self-Assessment and résumé sort served as prompts for reflection via semistructured interviews. Three themes were identified: (1) personal values were the foundation for developing professional values, which were further shaped by academic and clinical experiences, (2) core values were integrated into practice independent of practice setting and varied career paths, and (3) participants described the following professional core values as well integrated into their practice: integrity, compassion/caring, and accountability. Social responsibility was an area consistently identified as not being integrated into their practice. The Core Values Self-Assessment tool is a consensus-based document developed through a Delphi process. Future studies to establish reliability and construct validity of the tool may be warranted. Gaining an in-depth understanding of how practicing clinicians incorporate professional core values into clinical practice may shed light on the relationship between core values mastery and its impact on patient care. Findings may

  12. A progress report on progress files

    OpenAIRE

    East, Rob

    2005-01-01

    Abstract In order to facilitate personal development planning (PDP), the UK higher education sector is committed to introducing progress files. This article explores the experience of one institution in seeking to establish a system of progress files. It identifies the main practical problems in doing this, highlighting the lack of agreement on the skills that higher education students are expected to acqui...

  13. In-Core-Instrumentation Methods for 3-Dimensional Distribution Information of Reactor Core Temperatures and Melt-down

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Yeong Cheol [KHNP, Daejeon (Korea, Republic of); Eun, Myoung; Kim, Sung Jun [Woojin Inc., Hwaseong (Korea, Republic of)

    2014-08-15

    The tsunami-induced nuclear accident at Japanese Fukushima power plants in March 2011 has revealed some weaknesses in the severe accident monitoring system. The plant instrumentation did not provide utility, safety experts, and government officials with adequate and reliable information. The information on the reactor core damage and coolability is critical for making decisions correctly as well as in a timely manner during the course of the mitigation of severe accidents. Current Pressurized Water Reactor (PWR)s have an In-Core-Instrumentation (ICI) system that measures the temperature distribution of the top surface (i.e. Core Exit Temperatures) of the reactor core mainly to indicate when to begin Severe Accident Mitigation Guidelines (SAMG). This design concept giving only the core exit temperature has limitations in terms of sufficiency as well as availability of the information necessary for diagnosis on the status of the degraded core and the effectiveness of the measures taken as mitigation strategies. The reactor core exit temperatures are not sufficient to support the assessment of the degree of the core damage and the location of the molten core debris and recognition whether the core damage progresses on or it is mitigated. The ICI location being at the top of the reactor core also makes the ICI thermocouples vulnerable to melt-down because the upper part of the reactor core uncovers first, thereby melt down at the early stage of the accident. This means that direct indication of reactor core temperature will be lost and unavailable during the later stages of severe accident. To address the aforementioned weaknesses of the current ICIs, it is necessary to develop a new ICI system that provides information that is more expanded and more reliable for accident mitigation. With the enhanced information available, the SAMG can be prepared in more refined and effective way based on the direct and suitable indication of status of damages and the 3-dimensional

  14. Defining secondary progressive multiple sclerosis.

    Science.gov (United States)

    Lorscheider, Johannes; Buzzard, Katherine; Jokubaitis, Vilija; Spelman, Tim; Havrdova, Eva; Horakova, Dana; Trojano, Maria; Izquierdo, Guillermo; Girard, Marc; Duquette, Pierre; Prat, Alexandre; Lugaresi, Alessandra; Grand'Maison, François; Grammond, Pierre; Hupperts, Raymond; Alroughani, Raed; Sola, Patrizia; Boz, Cavit; Pucci, Eugenio; Lechner-Scott, Jeanette; Bergamaschi, Roberto; Oreja-Guevara, Celia; Iuliano, Gerardo; Van Pesch, Vincent; Granella, Franco; Ramo-Tello, Cristina; Spitaleri, Daniele; Petersen, Thor; Slee, Mark; Verheul, Freek; Ampapa, Radek; Amato, Maria Pia; McCombe, Pamela; Vucic, Steve; Sánchez Menoyo, José Luis; Cristiano, Edgardo; Barnett, Michael H; Hodgkinson, Suzanne; Olascoaga, Javier; Saladino, Maria Laura; Gray, Orla; Shaw, Cameron; Moore, Fraser; Butzkueven, Helmut; Kalincik, Tomas

    2016-09-01

    A number of studies have been conducted with the onset of secondary progressive multiple sclerosis as an inclusion criterion or an outcome of interest. However, a standardized objective definition of secondary progressive multiple sclerosis has been lacking. The aim of this work was to evaluate the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis, to enable comparability of future research studies. Using MSBase, a large, prospectively acquired, global cohort study, we analysed the accuracy of 576 data-derived onset definitions for secondary progressive multiple sclerosis and first compared these to a consensus opinion of three neurologists. All definitions were then evaluated against 5-year disease outcomes post-assignment of secondary progressive multiple sclerosis: sustained disability, subsequent sustained progression, positive disability trajectory, and accumulation of severe disability. The five best performing definitions were further investigated for their timeliness and overall disability burden. A total of 17 356 patients were analysed. The best definition included a 3-strata progression magnitude in the absence of a relapse, confirmed after 3 months within the leading Functional System and required an Expanded Disability Status Scale step ≥4 and pyramidal score ≥2. It reached an accuracy of 87% compared to the consensus diagnosis. Seventy-eight per cent of the identified patients showed a positive disability trajectory and 70% reached significant disability after 5 years. The time until half of all patients were diagnosed was 32.6 years (95% confidence interval 32-33.6) after disease onset compared with the physicians' diagnosis at 36 (35-39) years. The identified patients experienced a greater disease burden [median annualized area under the disability-time curve 4.7 (quartiles 3.6, 6.0)] versus non-progressive patients [1.8 (1.2, 1.9)]. This objective definition of secondary progressive multiple

  15. Study on core design for reduced-moderation water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Okubo, Tsutomu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-12-01

    The Reduced-Moderation Water Reactor (RMWR) is a water-cooled reactor with the harder neutron spectrum comparing with the LWR, resulting from low neutron moderation due to reduced water volume fraction. Based on the difference from the spectrum from the LWR, the conversion from U-238 to Pu-239 is promoted and the new cores preferable to effective utilization of uranium resource can be possible Design study of the RMWR core started in 1997 and new four core concepts (three BWR cores and one PWR core) are recently evaluated in terms of control rod worths, plutonium multiple recycle, high burnup and void coefficient. Comparative evaluations show needed incorporation of control rod programming and simplified PUREX process as well as development of new fuel cans for high burnup of 100 GW-d/t. Final choice of design specifications will be made at the next step aiming at realization of the RMWR. (T. Tanaka)

  16. C-terminal domain of hepatitis C virus core protein is essential for secretion

    Institute of Scientific and Technical Information of China (English)

    Soo-Ho Choi; Kyu-Jin Park; So-Yeon Kim; Dong-Hwa Choi; Jung-Min Park; Soon B. Hwang

    2005-01-01

    AIM: We have previously demonstrated that hepatitis C virus (HCV) core protein is efficiently released into the culture medium in insect cells. The objective of this study is to characterize the HCV core secretion in insect cells.METHODS: We constructed recombinant baculoviruses expressing various-length of mutant core proteins, expressed these proteins in insect cells, and examined core protein secretion in insect cells.RESULTS: Only wild type core was efficiently released into the culture medium, although the protein expression level of wild type core was lower than those of other mutant core proteins. We found that the shorter form of the core construct expressed the higher level of protein. However, if more than 18 amino acids of the core were truncated at the C-terminus,core proteins were no longer seareted into the culture medium.Membrane flotation data show that the secreted core proteins are associated with the cellular membrane protein, indicating that HCV core is secreted as a membrane complex.CONCLUSION: The C-terminal 18 amino acids of HCV core were crucial for core secretion into the culture media.Since HCV replication occurs on lipid raft membrane structure,these results suggest that HCV may utilize a unique core release mechanism to escape immune surveillance, thereby potentially representing the feature of HCV morphogenesis.

  17. Complex coacervate core micelles.

    Science.gov (United States)

    Voets, Ilja K; de Keizer, Arie; Cohen Stuart, Martien A

    2009-01-01

    In this review we present an overview of the literature on the co-assembly of neutral-ionic block, graft, and random copolymers with oppositely charged species in aqueous solution. Oppositely charged species include synthetic (co)polymers of various architectures, biopolymers - such as proteins, enzymes and DNA - multivalent ions, metallic nanoparticles, low molecular weight surfactants, polyelectrolyte block copolymer micelles, metallo-supramolecular polymers, equilibrium polymers, etcetera. The resultant structures are termed complex coacervate core/polyion complex/block ionomer complex/interpolyelectrolyte complex micelles (or vesicles); i.e., in short C3Ms (or C3Vs) and PIC, BIC or IPEC micelles (and vesicles). Formation, structure, dynamics, properties, and function will be discussed. We focus on experimental work; theory and modelling will not be discussed. Recent developments in applications and micelles with heterogeneous coronas are emphasized.

  18. Understanding core conductor fabrics

    Energy Technology Data Exchange (ETDEWEB)

    Swenson, D E, E-mail: deswenson@affinity-esd.com [Affinity Static Control Consulting, LLC 2609 Quanah Drive, Round Rock, Texas, 78681 (United States)

    2011-06-23

    ESD Association standard test method ANSI/ESD STM2.1 - Garments (STM2.1), provides electrical resistance test procedures that are applicable for materials and garments that have surface conductive or surface dissipative properties. As has been reported in other papers over the past several years{sup 1} fabrics are now used in many industries for electrostatic control purposes that do not have surface conductive properties and therefore cannot be evaluated using the procedures in STM2.1{sup 2}. A study was conducted to compare surface conductive fabrics with samples of core conductor fibre based fabrics in order to determine differences and similarities with regards to various electrostatic properties. This work will be used to establish a new work item proposal within WG-2, Garments, in the ESD Association Standards Committee in the USA.

  19. Task difficulty and inertial properties of hand-held tools: An assessment of their concurrent effects on precision aiming.

    Science.gov (United States)

    Silva, Paula L; Bootsma, Reinoud J; Figueiredo, Priscilla Rezende Pereira; Avelar, Bruna Silva; de Andrade, André Gustavo Pereira; Fonseca, Sérgio T; Mancini, Marisa Cotta

    2016-08-01

    Aiming hand-held tools at targets in space entails adjustments in the dynamical organization of aiming patterns according to the required precision. We asked whether and how these adjustments are modified by the tool's mass distribution. Twelve participants performed reciprocal aiming movements with a 50-cm long wooden probe. Kinematic patterns of probe movements were used as a window into the behavioral dynamic underlying performance of a reciprocal aiming task. We crossed three levels of task difficulty (IDs 2.8, 4.5 and 6.1) with two types of probe varying in their mass distribution (proximal vs distal loading). Movement duration was affected by task difficulty and probe loading (shorter for larger targets and proximal probe loading). Progressive deviations from a sinusoidal movement pattern were observed as task difficulty increased. Such deviations were more pronounced with proximal probe loading. Results point to a higher degree of non-linearity in aiming dynamics when the probe was loaded proximally, which might reflect employment of additional perceptual-motor processes to control the position of its less stable tip at the vicinity of the targets. More generally, the effects of probe loading on aiming pattern and dynamics suggest that perceptual-motor processes responding to task level constraints are sensitive to, and not independent from, biomechanical, end-effector constraints.

  20. Growth outside the core.

    Science.gov (United States)

    Zook, Chris; Allen, James

    2003-12-01

    Growth in an adjacent market is tougher than it looks; three-quarters of the time, the effort fails. But companies can change those odds dramatically. Results from a five-year study of corporate growth conducted by Bain & Company reveal that adjacency expansion succeeds only when built around strong core businesses that have the potential to become market leaders. And the best place to look for adjacency opportunities is inside a company's strongest customers. The study also found that the most successful companies were able to consistently, profitably outgrow their rivals by developing a formula for pushing out the boundaries of their core businesses in predictable, repeatable ways. Companies use their repeatability formulas to expand into any number of adjacencies. Some companies make repeated geographic moves, as Vodafone has done in expanding from one geographic market to another over the past 13 years, building revenues from $1 billion in 1990 to $48 billion in 2003. Others apply a superior business model to new segments. Dell, for example, has repeatedly adapted its direct-to-customer model to new customer segments and new product categories. In other cases, companies develop hybrid approaches. Nike executed a series of different types of adjacency moves: it expanded into adjacent customer segments, introduced new products, developed new distribution channels, and then moved into adjacent geographic markets. The successful repeaters in the study had two common characteristics. First, they were extraordinarily disciplined, applying rigorous screens before they made an adjacency move. This discipline paid off in the form of learning curve benefits, increased speed, and lower complexity. And second, in almost all cases, they developed their repeatable formulas by studying their customers and their customers' economics very, very carefully.

  1. Vascular contribution to Alzheimer disease: predictors of rapid progression.

    Science.gov (United States)

    Diomedi, Marina; Misaggi, Giulia

    2013-06-01

    Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.

  2. International Society on Thrombosis and Haemostasis core curriculum project: core competencies in clinical thrombosis and hemostasis.

    Science.gov (United States)

    McLintock, C; Pabinger, I; Bauer, K A; Laffan, M; Angchaisuksiri, P; Rezende, S M; Middeldorp, S; Ross, M

    2016-01-01

    Essentials The priority of ISTH was to establish a global core curriculum in thrombosis and hemostasis. International survey to determine competencies required for clinical specialists was carried out in the field. Competency framework provides a reference point for mapping and developing regional curricula. Core curriculum informs and links to a variety of ISTH educational materials. Background The International Society on Thrombosis and Haemostasis (ISTH) identified the need for an international core curriculum on thrombosis and hemostasis for its society members and the larger thrombosis and hemostasis community. Aims The current research sought consensus on the core competencies required by medical doctors who are ready to practise as independent clinical specialists in thrombosis and hemostasis with the aim of developing a core clinical curriculum for specialists in the field. Method A draft list of competencies was developed by the Working Group and formed the basis of an online survey. ISTH members and the larger thrombosis and hemostasis community were asked to rate the importance of each competency, on a Likert scale, for clinical specialists in thrombosis and hemostasis. Results There were a total of 644 responses to the online survey with broad geographical representation. There was general agreement on what level of competency would be required for clinical specialists in thrombosis and hemostasis at the specified level of training. Conclusions Using the survey to gain consensus on the level of competency required by clinical specialists in the field of thrombosis and hemostasis enabled the development of a core clinical curriculum that has been endorsed by the ISTH Council. The curriculum will offer a framework and international reference that will be used by the society, by national and regional organizations, and for further research. © 2015 International Society on Thrombosis and Haemostasis.

  3. Core Stabilization Training After Anterior Cruciate Ligament Reconstruction

    OpenAIRE

    Medeni, Özge Çınar; Bayramlar, Kezban; Baltacı, Gül; Yanmış, İbrahim

    2014-01-01

    Objectives: The aim of this study was to compare the effects of core stabilization exercises and conventional rehabilitation exercises after anterior cruciate ligament reconstruction in terms of knee joint laxity, knee muscle strength, postural stability and functional tests. Methods: Twenty eight patients reconstructed with hamstring tendon were included. Thirteen patients evaluated after a conventional rehabilitation and fifteen after a core stabilization programme. Single-limb postural sta...

  4. Advances in core drilling technology

    Science.gov (United States)

    Holdsworth, G.

    Some notable technical advances in drill design were reported at the meeting, held in Canada August 30-September 1, 1982, at the University of Calgary. Chief amongst these was a battery powered, computer assisted electromechanical core drill which has recently been used by the Danes in Greenland to continuously core to the base of the ice sheet at 2038 m. This is the deepest coring operation so far on the Greenland ice sheet. (The record for deep glacier drilling is held by the U.S. Army Cold Regions Research and Engineering Laboratory for the continuous coring through 2164 m of ice to bedrock at Byrd Station, Antarctica, in 1968). In early 1982, a current Soviet core drilling operation was reported to be at a depth of 2000 m at Vostok station, Antarctica, where the total ice thickness is about 4000 m; the goal of core drilling the entire ice thickness there could be achieved before the end of 1983.

  5. Heterogeneity in autism spectrum disorder: clarifying core- and co-occurring characteristics, correlates and course

    NARCIS (Netherlands)

    M.L.J.M. Eussen (Mart)

    2015-01-01

    markdownabstractThe first aim of this thesis is to gain more insight in the phenotypical variance of core and eo-occurring symptoms of ASD. The specific research questions concerning this first aim are: 1. Do symptom profiles on core ASD symptoms support a categorical view with different

  6. Characteristics of Misclassified CT Perfusion Ischemic Core in Patients with Acute Ischemic Stroke

    NARCIS (Netherlands)

    Geuskens, R.R.; Borst, J.; Lucas, M.; Boers, A.M.; Berkhemer, O.A.; Roos, Y.B.; Walderveen, M.A. van; Jenniskens, S.F.M.; Zwam, W.H. van; Dippel, D.W.; Majoie, C.B.; Marquering, H.A.

    2015-01-01

    BACKGROUND: CT perfusion (CTP) is used to estimate the extent of ischemic core and penumbra in patients with acute ischemic stroke. CTP reliability, however, is limited. This study aims to identify regions misclassified as ischemic core on CTP, using infarct on follow-up noncontrast CT. We aim to

  7. Evolution of iron core white dwarfs

    CERN Document Server

    Panei, J A; Benvenuto, O G

    1999-01-01

    Recent measurements made by Hipparcos (Provencal et al. 1998) present observational evidence supporting the existence of some white dwarf (WD) stars with iron - rich, core composition. In this connection, the present paper is aimed at exploring the structure and evolution of iron - core WDs by means of a detailed and updated evolutionary code. In particular, we examine the evolution of the central conditions, neutrino luminosity, surface gravity, crystallization, internal luminosity profiles and ages. We find that the evolution of iron - rich WDs is markedly different from that of their carbon - oxygen counterparts. In particular, cooling is strongly accelerated as compared with the standard case. Thus, if iron WDs were very numerous, some of them would have had time enough to evolve at lower luminosities than that corresponding to the fall - off in the observed WD luminosity function.

  8. Core TuLiP

    OpenAIRE

    Czenko, M.R.; Etalle, Sandro

    2007-01-01

    We propose CoreTuLiP - the core of a trust management language based on Logic Programming. CoreTuLiP is based on a subset of moded logic programming, but enjoys the features of TM languages such as RT; in particular clauses are issued by different authorities and stored in a distributed manner. We present a lookup and inference algorithm which we prove to be correct and complete w.r.t. the declarative semantics. CoreTuLiP enjoys uniform syntax and the well-established semantics and is express...

  9. Biochemistry Instrumentation Core Technology Center

    Data.gov (United States)

    Federal Laboratory Consortium — The UCLA-DOE Biochemistry Instrumentation Core Facility provides the UCLA biochemistry community with easy access to sophisticated instrumentation for a wide variety...

  10. Synthetic observations of first hydrostatic cores in collapsing low-mass dense cores. I. Spectral energy distributions and evolutionary sequence

    OpenAIRE

    Commercon, Benoit; Launhardt, Ralf; Dullemond, Cornelis P.; Henning, Thomas

    2012-01-01

    The low-mass star formation evolutionary sequence is relatively well-defined both from observations and theoretical considerations. The first hydrostatic core is the first protostellar equilibrium object that is formed during the star formation process. Using state-of-the-art radiation-magneto-hydrodynamic 3D adaptive mesh refinement calculations, we aim to provide predictions for the dust continuum emission from first hydrostatic cores. We investigate the collapse and the fragmentation of ma...

  11. COOL CORE CLUSTERS FROM COSMOLOGICAL SIMULATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Rasia, E.; Borgani, S.; Murante, G.; Planelles, S.; Biffi, V.; Granato, G. L. [INAF, Osservatorio Astronomico di Trieste, via Tiepolo 11, I-34131, Trieste (Italy); Beck, A. M.; Steinborn, L. K.; Dolag, K. [Universitäts-Sternwarte München, Scheinerstr.1, D-81679 München (Germany); Ragone-Figueroa, C., E-mail: rasia@oats.inaf.it [Instituto de Astronomá Teórica y Experimental (IATE), Consejo Nacional de Investigaciones Cientiíficas y Técnicas de la República Argentina (CONICET), Observatorio Astronómico, Universidad Nacional de Córdoba, Laprida 854, X5000BGR, Córdoba (Argentina)

    2015-11-01

    We present results obtained from a set of cosmological hydrodynamic simulations of galaxy clusters, aimed at comparing predictions with observational data on the diversity between cool-core (CC) and non-cool-core (NCC) clusters. Our simulations include the effects of stellar and active galactic nucleus (AGN) feedback and are based on an improved version of the smoothed particle hydrodynamics code GADGET-3, which ameliorates gas mixing and better captures gas-dynamical instabilities by including a suitable artificial thermal diffusion. In this Letter, we focus our analysis on the entropy profiles, the primary diagnostic we used to classify the degree of cool-coreness of clusters, and the iron profiles. In keeping with observations, our simulated clusters display a variety of behaviors in entropy profiles: they range from steadily decreasing profiles at small radii, characteristic of CC systems, to nearly flat core isentropic profiles, characteristic of NCC systems. Using observational criteria to distinguish between the two classes of objects, we find that they occur in similar proportions in both simulations and observations. Furthermore, we also find that simulated CC clusters have profiles of iron abundance that are steeper than those of NCC clusters, which is also in agreement with observational results. We show that the capability of our simulations to generate a realistic CC structure in the cluster population is due to AGN feedback and artificial thermal diffusion: their combined action allows us to naturally distribute the energy extracted from super-massive black holes and to compensate for the radiative losses of low-entropy gas with short cooling time residing in the cluster core.

  12. Waves in the core and mechanical core-mantle interactions

    DEFF Research Database (Denmark)

    Jault, D.; Finlay, Chris

    2015-01-01

    the motions in the direction parallel to the Earth'srotation axis. This property accounts for the signicance of the core-mantle topography.In addition, the stiening of the uid in the direction parallel to the rotation axis gives riseto a magnetic diusion layer attached to the core-mantle boundary, which would...

  13. Characterizing the Core via K-Core Covers

    NARCIS (Netherlands)

    Sanchez, S.M.; Borm, P.E.M.; Estevez, A.

    2013-01-01

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  14. Characterizing the Core via K-Core Covers

    NARCIS (Netherlands)

    Sanchez, S.M.; Borm, P.E.M.; Estevez, A.

    2013-01-01

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  15. LC21-Hopes and Cautions for the Library of Congress; The NSF National Science, Mathematics, Engineering, and Technology Education Digital Library (NSDL) Program: A Progress Report; A Grammar of Dublin Core; Measuring the Impact of an Electronic Journal Collection on Library Costs: A Framework and Preliminary Observations; Emulation As a Digital Preservation Strategy.

    Science.gov (United States)

    O'Donnell, James J.; Zia, Lee L.; Baker, Thomas; Montgomery, Carol Hansen; Granger, Stewart

    2000-01-01

    Includes five articles: (1) discusses Library of Congress efforts to include digital materials; (2) describes the National Science Foundation (NSF) digital library program to improve science, math, engineering, and technology education; (3) explains Dublin Core grammar; (4) measures the impact of electronic journals on library costs; and (5)…

  16. Digital Preservation and Deep Infrastructure; Dublin Core Metadata Initiative Progress Report and Workplan for 2002; Video Gaming, Education and Digital Learning Technologies: Relevance and Opportunities; Digital Collections of Real World Objects; The MusArt Music-Retrieval System: An Overview; eML: Taking Mississippi Libraries into the 21st Century.

    Science.gov (United States)

    Granger, Stewart; Dekkers, Makx; Weibel, Stuart L.; Kirriemuir, John; Lensch, Hendrik P. A.; Goesele, Michael; Seidel, Hans-Peter; Birmingham, William; Pardo, Bryan; Meek, Colin; Shifrin, Jonah; Goodvin, Renee; Lippy, Brooke

    2002-01-01

    One opinion piece and five articles in this issue discuss: digital preservation infrastructure; accomplishments and changes in the Dublin Core Metadata Initiative in 2001 and plans for 2002; video gaming and how it relates to digital libraries and learning technologies; overview of a music retrieval system; and the online version of the…

  17. The role of education at the aiming of the european unity: the enlighted and romantic perpetual peace projects

    Directory of Open Access Journals (Sweden)

    María José REBOLLO ESPINOSA

    2013-11-01

    Full Text Available The sources of the peace education goes back far enoug. This article aims to analyzing some perpetual peace projects which were actually written beetween the XVII and XX centuries. Those projects, being regarded as a proper means in order to attain the european unity, may be viewed as antecedents of the today peace conferences. It is, then, acknowledged, that what started as a human desire for international agreement is progressively achieved and it is purported to show the role this particular dynamics plays in the education.

  18. Relativistic frozen core potential scheme with relaxation of core electrons

    Science.gov (United States)

    Nakajima, Yuya; Seino, Junji; Hayami, Masao; Nakai, Hiromi

    2016-10-01

    This letter proposes a relaxation scheme for core electrons based on the frozen core potential method at the infinite-order Douglas-Kroll-Hess level, called FCP-CR. The core electrons are self-consistently relaxed using frozen molecular valence potentials after the valence SCF calculation is performed. The efficiency of FCP-CR is confirmed by calculations of gold clusters. Furthermore, FCP-CR reproduces the results of the all-electron method for the energies of coinage metal dimers and the core ionization energies and core level shifts of vinyl acetate and three tungsten complexes at the Hartree-Fock and/or symmetry-adapted cluster configuration interaction levels.

  19. Characteristics of High-Pressure Microwave Glow Discharge in a Microgap Aimed at VUV Light Source

    Science.gov (United States)

    Kono, Akihiro

    2004-09-01

    In continuous high-pressure discharge at high plasma densities, the gas and electron temperatures tend to be in equilibrium and the current path tends to constrict. However, using microdischarge with microwave excitation, we can produce a cw high-density non-equilibrium plasma extending one-dimensionally over some length. We are studying such a plasma aiming at producing a high-brightness VUV excimer light source. The plasma is produced in a microgap ( ˜ 100 μm) between two 10-mm-long knife-edge electrodes at a very high power deposition ( ˜ MW/cm^3). VUV emission from Ar2 and Xe2 was confirmed using discharge with Ar/He and Xe/He mixture gases. To understand the properties of the microgap discharge, detailed optical diagnostics are being carried out. Spatially resolved Thomson and Raman scattering measurements showed that the electron density in a 100 W He discharge is 3× 10^14 cm-3 and the gas temperature is 1200K. The gas temperature was also studied as a function of the gas flow rate through the microgap using N2 C^3Π-B^3Π optical emission. A rather surprising result is that the gas temperature is relatively insensitive to the gas flow rate even if the flow is rapid enough to replace the gas in the microgap within the characteristic time of diffusive heat conduction to the wall. This suggests the existence of a rapid heat transport mechanism in the discharge other than diffusive heat conduction. The existence of an extremely large gas-temperature garadient between the plasma and the wall may induce a rapid convective heat transport. A computational study of the heat transport mechanism in the microgap discharge is also in progress (Work supported by a Grant-in-Aid for Scientific Research of Priority Areas [15075205] from MEXT Japan)

  20. What is interaction science? Revisiting the aims and scope of JoIS

    Directory of Open Access Journals (Sweden)

    Gisela Susanne Bahr

    2016-12-01

    Full Text Available Abstract Interaction Science has undergone rapid development since JoIS’ (the Journal of Interaction Science founding in 2013. The advent of novel techniques and tools required reviewing the understanding of Interaction Science and the scope and aims of JoIS. More particularly, the set of methods and frameworks needed to be revisited and checked against the characteristics of today’s ecological system and the resulting requirements for developing socio-technical systems. In this editorial, we tackle the interdisciplinary nature of Human-Computer-Interaction, the different thematic areas in Interaction Science, and diverse scientific research methods (and methodologies. We also examine the JoIS articles published so far, in order to provide a sound baseline for re-defining Interaction Science and update the mission of JoIS accordingly. The newly proposed definition of Interaction Science explicitly takes into account diversity and transdisciplinarity of interactional phenomena. We recognize the action space of Interaction Science being complex and ever-changing, and thus opt for wide generalization. Such way, the interaction is considered as the exchange of material or immaterial goods between acting parties (biological or technical entities embodied in a certain context. Regarding scientific methodology, one of the important proposals relevant to JoIS is to relax emphasize on the use of empirical investigation based on traditional laboratory experiment. Traditional laboratory empiricism (usually empowered by statistics and hypothesis testing is too restrictive to exclusively represent JoIS’ aims and scope, so we make way to complementary methods such as modeling, simulation, case studies, and design as science. By acknowledging studies of new methodologies, metrics and measurements, as well as work grounded in theories and applications, we ask for future contributors to stay committed to the TEAM (Theory advancement, Empirical advancement

  1. [Postoperative pain management. Aims and organization of a strategy for postoperative acute pain therapy].

    Science.gov (United States)

    Nolli, M; Nicosia, F

    2000-09-01

    The Health Services, not only the Italian one, is under pressure because of request for improving treatment quality and the financial need for reorganization and cost-saving. It's required a rationalization of intervention, together with a careful choice of the best and cheapest techniques and the demonstration of their efficacy. The anaesthesia service activity, in a period of cost rationalization and funds restriction should be aimed to appropriate outcome measures corrected by both patient's risk factors and surgical-anaesthesiological case-mix. The development of a complete strategy for surgical pain management might run into two phases. The first phase, internal and mono-specialistic, should develop like the creation of an Acute Pain Team. The main processes are: focusing the problem (charge of the care), training, information, teaching methodology (timing, methods, drugs, techniques, etc.) and the audit (before and after changes). The main aims are the evaluation of the level of analgesia and pain relief or patient's satisfaction which are partial endpoints useful to demonstrate the improvement and the efficacy of the new pain management strategies. The second phase, multidisciplinary, is directed toward the creation of a Postoperative Evaluation Team. The main objective is to set up a collaborative clinical group able to identify the criteria for quality, efficacy and safety. The major purpose is the evaluation of major outcome measures: surgical outcome, morbidity, mortality and length of hospitalization. The improvement in the quality of postoperative pain treatment goes through a better organization and a progressive increase of the already available therapy. The achievement of the result and the quality projects depend on the interaction among staff members with different behaviours and settings. Internal teaching and training, continuous education for doctors and nurses, and external information, marketing and improvement of attractive capability of

  2. Adult educators' core competences

    Science.gov (United States)

    Wahlgren, Bjarne

    2016-06-01

    Which competences do professional adult educators need? This research note discusses the topic from a comparative perspective, finding that adult educators' required competences are wide-ranging, heterogeneous and complex. They are subject to context in terms of national and cultural environment as well as the kind of adult education concerned (e.g. basic education, work-related education etc.). However, it seems that it is possible to identify certain competence requirements which transcend national, cultural and functional boundaries. This research note summarises these common or "core" requirements, organising them into four thematic subcategories: (1) communicating subject knowledge; (2) taking students' prior learning into account; (3) supporting a learning environment; and (4) the adult educator's reflection on his or her own performance. At the end of his analysis of different competence profiles, the author notes that adult educators' ability to train adult learners in a way which then enables them to apply and use what they have learned in practice (thus performing knowledge transfer) still seems to be overlooked.

  3. Geography, History, and the Aims of Education: The Possibility of Multiculturalism in "Democracy and Education"

    Science.gov (United States)

    Pratt, Scott L.

    2016-01-01

    In this essay, Scott Pratt develops the tension at work in "Democracy and Education" between conceptions of multiculturalism that emerge from Dewey's commitment to progress as a process of civilization and from his contrasting commitment to a vision of progress as a localized process that requires respect for boundaries and limits. The…

  4. Geography, History, and the Aims of Education: The Possibility of Multiculturalism in "Democracy and Education"

    Science.gov (United States)

    Pratt, Scott L.

    2016-01-01

    In this essay, Scott Pratt develops the tension at work in "Democracy and Education" between conceptions of multiculturalism that emerge from Dewey's commitment to progress as a process of civilization and from his contrasting commitment to a vision of progress as a localized process that requires respect for boundaries and limits. The…

  5. Laying the foundations for greener transport - TERM 2011: transport indicators tracking progress towards environmental targets in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Vicente, A.

    2011-11-15

    For the first time ever the European Commissions is proposing a greenhouse gas emissions target for transport. But how is transport going to provide the services that our society needs while minimising its environmental impacts? This is the theme for the Transport White Paper launched in 2011. TERM 2011 and future reports aim to deliver an annual assessment on progress towards these targets by introducing the Transport and Environment Reporting Mechanism Core Set of Indicators (TERM-CSI). TERM 2011 provides also the baseline to which progress will be checked against, covering most of the environmental areas, including energy consumption, emissions, noise and transport demand. In addition, this report shows latest data and discuss on the different aspects that can contribute the most to minimise transport impacts. TERM 2011 applies the avoid-shift-improve (ASI) approach, introduced in the previous TERM report, analysing ways to optimise transport demand, obtain a more sustainable modal split or use the best technology available. (Author)

  6. Maximum stellar iron core mass

    Indian Academy of Sciences (India)

    F W Giacobbe

    2003-03-01

    An analytical method of estimating the mass of a stellar iron core, just prior to core collapse, is described in this paper. The method employed depends, in part, upon an estimate of the true relativistic mass increase experienced by electrons within a highly compressed iron core, just prior to core collapse, and is significantly different from a more typical Chandrasekhar mass limit approach. This technique produced a maximum stellar iron core mass value of 2.69 × 1030 kg (1.35 solar masses). This mass value is very near to the typical mass values found for neutron stars in a recent survey of actual neutron star masses. Although slightly lower and higher neutron star masses may also be found, lower mass neutron stars are believed to be formed as a result of enhanced iron core compression due to the weight of non-ferrous matter overlying the iron cores within large stars. And, higher mass neutron stars are likely to be formed as a result of fallback or accretion of additional matter after an initial collapse event involving an iron core having a mass no greater than 2.69 × 1030 kg.

  7. The INTEGRAL Core Observing Programme

    OpenAIRE

    Winkler, C; Gehrels, N.; Lund, N.; Schoenfelder, V.; Ubertini, P.

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements of the observing programme.

  8. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...

  9. Complicated Politics to the Core

    Science.gov (United States)

    McGuinn, Patrick

    2015-01-01

    People dislike the Common Core for several different reasons, and so it is important to disaggregate the sources of opposition and to assess and then to dispel some of the myths that have built up around it. It also is important to understand the unusual political alliances that have emerged in opposition to Common Core implementation and how they…

  10. Common Core: Victory Is Yours!

    Science.gov (United States)

    Fink, Jennifer L. W.

    2012-01-01

    In this article, the author discusses how to implement the Common Core State Standards in the classroom. She presents examples and activities that will leave teachers feeling "rosy" about tackling the new standards. She breaks down important benchmarks and shows how other teachers are doing the Core--and loving it!

  11. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...

  12. Complicated Politics to the Core

    Science.gov (United States)

    McGuinn, Patrick

    2015-01-01

    People dislike the Common Core for several different reasons, and so it is important to disaggregate the sources of opposition and to assess and then to dispel some of the myths that have built up around it. It also is important to understand the unusual political alliances that have emerged in opposition to Common Core implementation and how they…

  13. Artemisia: Active and Interactive Monitoring of the Forests in Protected Areas Aimed at the Sustainable Management of Nature

    Directory of Open Access Journals (Sweden)

    Clelia Cirillo

    2014-12-01

    Full Text Available To pursue the usage of forests resources in the processes of economic and social development it is determining that the principles of natural heritage protection join in a concept of progress, based on evolution and technological innovation; the realization of innovative investigation and representation tools turns out to be useful to ease the integration of forests’ resources in shared development processes aimed at enhancing the cooperation of local actors, and to ease the territory’s sustainable growth and the development of the natural heritage. The integrated management of the actions aimed at protecting and easing the ecologic and recreative functioning of forests, which are increasingly exposed to pressures caused by several catastrophic factors, requires the tuning of modelling and active monitoring systems of the forests based on social networks and volunteering for the processes of data updating.

  14. Progressive collapse and methods of prevention

    OpenAIRE

    Vasilieva, Anastasia

    2013-01-01

    The purpose of the study was to describe the process of progressive collapse and to find more methods and approaches to design the structure for preventing from this kind of failure. And the last aim was to find Russian norms and standards and make calculations on progressive collapse of the trade center, according to them. In this way the work was commissioned by Finnmap Consulting Oy. The thesis should be interesting to design engineers working with designing the large-span structures o...

  15. Core body temperature in obesity.

    Science.gov (United States)

    Heikens, Marc J; Gorbach, Alexander M; Eden, Henry S; Savastano, David M; Chen, Kong Y; Skarulis, Monica C; Yanovski, Jack A

    2011-05-01

    A lower core body temperature set point has been suggested to be a factor that could potentially predispose humans to develop obesity. We tested the hypothesis that obese individuals have lower core temperatures than those in normal-weight individuals. In study 1, nonobese [body mass index (BMI; in kg/m(2)) temperature-sensing capsules, and we measured core temperatures continuously for 24 h. In study 2, normal-weight (BMI of 18-25) and obese subjects swallowed temperature-sensing capsules to measure core temperatures continuously for ≥48 h and kept activity logs. We constructed daily, 24-h core temperature profiles for analysis. Mean (±SE) daily core body temperature did not differ significantly between the 35 nonobese and 46 obese subjects (36.92 ± 0.03°C compared with 36.89 ± 0.03°C; P = 0.44). Core temperature 24-h profiles did not differ significantly between 11 normal-weight and 19 obese subjects (P = 0.274). Women had a mean core body temperature ≈0.23°C greater than that of men (36.99 ± 0.03°C compared with 36.76 ± 0.03°C; P body temperature. It may be necessary to study individuals with function-altering mutations in core temperature-regulating genes to determine whether differences in the core body temperature set point affect the regulation of human body weight. These trials were registered at clinicaltrials.gov as NCT00428987 and NCT00266500.

  16. On the fidelity of the core mass functions derived from dust column density data

    CERN Document Server

    Kainulainen, J; Rathborne, J M; Alves, J F

    2009-01-01

    Aims: We examine the recoverability and completeness limits of the dense core mass functions (CMFs) derived for a molecular cloud using extinction data and a core identification scheme based on two-dimensional thresholding. Methods: We performed simulations where a population of artificial cores was embedded into the variable background extinction field of the Pipe nebula. We extracted the cores from the simulated extinction maps, constructed the CMFs, and compared them to the input CMFs. The simulations were repeated using a variety of extraction parameters and several core populations with differing input mass functions and differing degrees of crowding. Results: The fidelity of the observed CMF depends on the parameters selected for the core extraction algorithm for our background. More importantly, it depends on how crowded the core population is. We find that the observed CMF recovers the true CMF reliably when the mean separation of cores is larger than their mean diameter (f>1). If this condition holds...

  17. [Does neuroendocrine differentiation have prognostic value in prostate core needle biopsies?].

    Science.gov (United States)

    Jaskulski, Jarosław; Gołabek, Tomasz; Kopczyński, Janusz; Orłowsk, Pawel; Bukowczan, Jakub; Dudek, Przemek; Chłosta, Piotr

    2013-01-01

    The biological behaviour of prostate cancer (PCa) varies significantly and cannot be, therefore, predicted. Better understanding of the mechanisms underpinning PCa oncogenesis and progression with its yet-to-be discovered poor prognostic factors is essential in order to optimise and tailor treatment to an individual patient. The aim of this paper was to investigate the association between the rate of focal PCa neuroendocrine activity, tumour cell proliferation index score, and the rate of PCa positive core needle biopsy results. 92 men, with histologically confirmed PCa, which was clinically confined to the prostate and was graded with Gleason score > or =7, had their core needle biopsies under transrectal ultrasonography guidance performed. The PCa neuroendocrine activity was immunohistochemically confirmed using antibodies against Chromogranin-A and neuron specific enolase. The neuroendocrine activity was detected in 14 (13%) out of 92 PCa patients participating in the study. The proliferative index was not increased in non-cancerous prostate cells. There was no relationship between PCa neuroendocrine activity, the number and percentage of PCa positive biopsies, prostate volume, serum PSA concentration, and Gleason score found. No association between selected PCa prognostic factors and neuroendocrine activity could be found in patients with organ confined prostate cancer.

  18. Performance of a core of transversal skills: self-perceptions of undergraduate medical students.

    Science.gov (United States)

    Ribeiro, Laura; Severo, Milton; Ferreira, Maria Amélia

    2016-01-15

    There is an increasingly growing trend towards integrating scientific research training into undergraduate medical education. Communication, research and organisational/learning skills are core competences acquired by scientific research activity. The aim of this study was to assess the perceived performance of a core of transversal skills, related with scientific research, by Portuguese medical students. A cross-sectional study was conducted in 611 Portuguese students attending the first, fourth and sixth years of the medical course, during the same academic year. A validated questionnaire was applied for this purpose. Medical students felt confident regarding the majority of the analyzed transversal skills, particularly regarding team work capacity (72.7% perceived their own capacity as good). On the other hand, the perceived ability to manage information technology, time and to search literature was classified only as sufficient by many of them. The progression over the medical course and participation in research activities were associated with an increasing odds of a good perceived performance of skills such as writing skills (research activity: OR = 2.00; 95% CI: 1.34-2.97) and English proficiency (research activity: OR = 1.59; 95% CI: 1.06-2.38/final year medical students: OR = 3.63; 95% CI: 2.42-5.45). In this line, the early exposure to research activities along undergraduate medical education is an added value for students and the implementation of an integrated research program on medical curriculum should be considered.

  19. Core outcome sets in women's and newborn health: a systematic review.

    Science.gov (United States)

    Duffy, Jmn; Rolph, R; Gale, C; Hirsch, M; Khan, K S; Ziebland, S; McManus, R J

    2017-09-01

    Variation in outcome collection and reporting is a serious hindrance to progress in our specialty; therefore, over 80 journals have come together to support the development, dissemination, and implementation of core outcome sets. This study systematically reviewed and characterised registered, progressing, or completed core outcome sets relevant to women's and newborn health. Systematic search using the Core Outcome Measures in Effectiveness Trial initiative and the Core Outcomes in Women's and Newborn Health initiative databases. Registry entries, protocols, systematic reviews, and core outcome sets. Descriptive statistics to describe characteristics and results. There were 49 core outcome sets registered in maternal and newborn health, with the majority registered in 2015 (n = 22; 48%) or 2016 (n = 16; 32%). Benign gynaecology (n = 8; 16%) and newborn health (n = 3; 6%) are currently under-represented. Twenty-four (52%) core outcome sets were funded by international (n = 1; core outcome sets were completed: reconstructive breast surgery (11 outcomes), preterm birth (13 outcomes), epilepsy in pregnancy (29 outcomes), and maternity care (48 outcomes). The quantitative, qualitative, and consensus methods used to develop core outcome sets varied considerably. Core outcome sets are currently being developed across women's and newborn health, although coverage of topics is variable. Development of further infrastructure to develop, disseminate, and implement core outcome sets is urgently required. Forty-nine women's and newborn core outcome sets registered. 50% funded. 7 protocols, 20 systematic reviews, and 4 core outcome sets published. @coreoutcomes @jamesmnduffy. © 2017 Royal College of Obstetricians and Gynaecologists.

  20. Synthetic observations of first hydrostatic cores in collapsing low-mass dense cores. I. Spectral energy distributions and evolutionary sequence

    Science.gov (United States)

    Commerçon, B.; Launhardt, R.; Dullemond, C.; Henning, Th.

    2012-09-01

    Context. The low-mass star formation evolutionary sequence is relatively well-defined both from observations and theoretical considerations. The first hydrostatic core is the first protostellar equilibrium object that is formed during the star formation process. Aims: Using state-of-the-art radiation-magneto-hydrodynamic 3D adaptive mesh refinement calculations, we aim to provide predictions for the dust continuum emission from first hydrostatic cores. Methods: We investigated the collapse and the fragmentation of magnetized 1 M⊙ prestellar dense cores and the formation and evolution of first hydrostatic cores using the RAMSES code. We used three different magnetization levels for the initial conditions, which cover a wide variety of early evolutionary morphology, e.g., the formation of a disk or a pseudo-disk, outflow launching, and fragmentation. We post-processed the dynamical calculations using the 3D radiative transfer code RADMC-3D. We computed spectral energy distributions and usual evolutionary stage indicators such as bolometric luminosity and temperature. Results: We find that the first hydrostatic core lifetimes depend strongly on the initial magnetization level of the parent dense core. We derive, for the first time, spectral energy distribution evolutionary sequences from high-resolution radiation-magneto-hydrodynamic calculations. We show that under certain conditions, first hydrostatic cores can be identified from dust continuum emission at 24 μm and 70 μm. We also show that single spectral energy distributions cannot help in distinguishing between the formation scenarios of the first hydrostatic core, i.e., between the magnetized and non-magnetized models. Conclusions: Spectral energy distributions are a first useful and direct way to target first hydrostatic core candidates but high-resolution interferometry is definitively needed to determine the evolutionary stage of the observed sources.

  1. COSIS: COre State Indication System

    Energy Technology Data Exchange (ETDEWEB)

    Cho, J. Y.; Lee, K. B.; Koo, B. S.; Lee, W. K.; Lee, C. C; Zee, S. Q

    2006-02-15

    COSIS (COre State Indication System) which implemented in the SMART research reactor plays a role to supply the core state parameters or graphs for the operator to recognize the core state effectively. The followings are the main functions of COSIS. (1) Validity Check for the Process Signals and Determination of the COSIS Inputs (SIGVAL) (2) Coolant Flow Rate Calculation (FLOW) (3) Core Thermal Power Calculation (COREPOW) (4) In-core 3-Dimensional Power Distribution Calculation and Peaking Parameters Generation (POWER3D) (5) Azimuthal Tilt Calculation (AZITILT). This report describes the methodology of COSIS which produces the core state parameters using the process and detector signals. In the SIGVAL module, COSIS checks most signals except for the CEA position and determines the input signals. In the FLOW module, the corelation coefficient between the RPM signal and coolant flow is updated from the energy balance at the steam generator, and the coolant flow rate is calculated using the RPM signal. In the COREPOW module, the secondary calorimetric power, the primary {delta}T power and the ex-core power are calculated, and the final core thermal power and biased core power are determined. In the POWER3D module, the 3-dimensional power distribution is calculated using the in-core detector signal, and the 3-D peaking factor, 2-D radial peaking factor, axial offset, maximum linear power density are produced. In the AZITILT module, the arithmetic averaged and vector averaged azimuthal tilts are calculated, and the final tilt is determined. The COSIS performance test of the COSIS is performed for the temperature compensation method, the COREPOW and the POWER3D modules. The test for the temperature compensation method is performed for the temperature variations of the linear, parabolic, exponential, sine function. The test shows that the implemented temperature compensation method works soundly. The COREPOW test is performed by varying the core power from the initial

  2. Timing And Processes Of Earth's Core Differentiation.

    Science.gov (United States)

    Allegre, C. J.; Manhes, G.; Gopel, C.

    2004-12-01

    iron-sulphur compounds of 5 vol% solid olivine, through channel on triple junction between minerals. This study allows us to reconsider the precedent proposition (Stevenson, 1990) based on experimental and theoretical considerations suggesting that percolation of metallic iron rich liquid through a mostly solid silicate matrix is largely prevented because of the high surface tension of iron. During formation and segregation of the Fe-FeS eutectic, W isotopic equilibration is limited by the diffusion through the solid silicate matrix. During the further Earth's growth, impact melting increased and has induced a progressive melting of BSE up to the formation of magma ocean at the end of the planet's accretion. Before the occurrence of the magma ocean, W equilibration between impactors and BSE has not been complete This incomplete isotopic exchange between terrestrial metal and metal originating from impactors with solid part of BSE during early accretion of the Earth leads to the observed excess of 182W of present BSE. It occurs when the 182W production in BSE is most significant, due to the short half-life of 182Hf. The change of segregation mechanisms of Earth's core during planet's growth and short-sightedness of Hf-W chronometer focused to the early segregation of Earth's core make the divergence with the U-Pb and I-Xe terrestrial records. Yin et al. 2002, Nature 418, 949-952. Kleine et al. 2002, Nature 418, 952-955. Schoenberg et al. 2002, Geochim. Cosmochim. Acta 66, 3151-3160. Wetherill 1986, in Origin of the Moon, eds Hartmann et al., LPI, 519-550. Yoshino et al. 2003, Nature 422, 154-157. Stevenson 1990, in Origin of the Earth, eds Newson et al., LPI, 231-249.

  3. Investigation of geomagnetic field forecasting and fluid dynamics of the core. [determination of the bundary between the core and mantle of the Earth

    Science.gov (United States)

    Benton, E. R. (Principal Investigator)

    1981-01-01

    Progress in the use of MAGSAT data to confirm that the radius of the Earth's core-mantle boundary can be accurately determined magnetically is reported. The MAGSAT data was used in conjunction with a high quality manfield model for epoch 1965. The unsigned flux linking the core and mantle of the Earth is considered to be a legitimate invariant for a span of time. The value from MAGSAT of this constant is 16.056 GWb (gigawebers).

  4. Epistemology and ontology in core ontologies: FOLaw and LRI-Core, two core ontologies for law

    NARCIS (Netherlands)

    Breukers, J.A.P.J.; Hoekstra, R.J.

    2004-01-01

    For more than a decade constructing ontologies for legal domains, we, at the Leibniz Center for Law, felt really the need to develop a core ontology for law that would enable us to re-use the common denominator of the various legal domains. In this paper we present two core ontologies for law. The

  5. Human Core Temperature Prediction for Heat-Injury Prevention

    Science.gov (United States)

    2015-05-01

    injuries across the services, including 311 cases of heat stroke . The risk of heat injury is modulated by both intrinsic factors (such as genetics... Biotechnology High Performance Computing Software Applications Insti- tute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research...stress (beyond 37 °C), progressing to hyperthermia and heat exhaustion (beyond 39 °C), and then to heat stroke (beyond 40 °C) [2]. The rising core

  6. Electrospinning of ultrafine core/shell fibers for biomedical applications

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Because of the inherent appearance similar to the natural extracellular matrix,ultrafine fibrous membranes prepared via electrospinning exhibit widespread applications,especially in the biomedical area.Extensional modifications of coaxial and emulsion electrospinning have drawn much attention in preparation of core/shell fibers for applications as tissue engineering scaffolds and controlled delivery systems for bioactive substances.Due to incorporation of multi-components in the electrospun core/ shell fibers,the process of coaxial and emulsion electrospinning became more susceptible.The theories have not been fully understood.A series of investigations were carried out evaluating the systematic and processing parameters.This paper reviews advantages and potentials of electrospun core/shell fibers as well as factors influencing their formation on the basis of our research and new progress.

  7. Core-Collapse Supernovae, Neutrinos, and Gravitational Waves

    CERN Document Server

    Ott, C D; Gossan, S; Abdikamalov, E; Gamma, U C T; Drasco, S

    2012-01-01

    Core-collapse supernovae are among the most energetic cosmic cataclysms. They are prodigious emitters of neutrinos and quite likely strong galactic sources of gravitational waves. Observation of both neutrinos and gravitational waves from the next galactic or near extragalactic core-collapse supernova will yield a wealth of information on the explosion mechanism, but also on the structure and angular momentum of the progenitor star, and on aspects of fundamental physics such as the equation of state of nuclear matter at high densities and low entropies. In this contribution to the proceedings of the Neutrino 2012 conference, we summarize recent progress made in the theoretical understanding and modeling of core-collapse supernovae. In this, our emphasis is on multi-dimensional processes involved in the explosion mechanism such as neutrino-driven convection and the standing accretion shock instability. As an example of how supernova neutrinos can be used to probe fundamental physics, we discuss how the rise ti...

  8. Routine versus aggressive upstream rhythm control for prevention of early atrial fibrillation in heart failure : background, aims and design of the RACE 3 study

    NARCIS (Netherlands)

    Alings, M.; Smit, M. D.; Moes, M. L.; Crijns, H. J. G. M.; Tijssen, J. G. P.; Brugemann, J.; Hillege, H. L.; Lane, D. A.; Lip, G. Y. H.; Smeets, J. R. L. M.; Tieleman, R. G.; Tukkie, R.; Willems, F. F.; Vermond, R. A.; Van Veldhuisen, D. J.; Van Gelder, I. C.

    2013-01-01

    Rhythm control for atrial fibrillation (AF) is cumbersome because of its progressive nature caused by structural remodelling. Upstream therapy refers to therapeutic interventions aiming to modify the atrial substrate, leading to prevention of AF. The Routine versus Aggressive upstream rhythm Control

  9. Cancer Moonshot Aims to Double Pace of Research | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... stage. NIH MedlinePlus magazine sat down with Dinah Singer, PhD, one of the three co-chairs of ... Biology, to learn about its progress. Dr. Dinah Singer, co-chair of the National Cancer Moonshot Initiative ...

  10. Multi-Core Cache Hierarchies

    CERN Document Server

    Balasubramonian, Rajeev

    2011-01-01

    A key determinant of overall system performance and power dissipation is the cache hierarchy since access to off-chip memory consumes many more cycles and energy than on-chip accesses. In addition, multi-core processors are expected to place ever higher bandwidth demands on the memory system. All these issues make it important to avoid off-chip memory access by improving the efficiency of the on-chip cache. Future multi-core processors will have many large cache banks connected by a network and shared by many cores. Hence, many important problems must be solved: cache resources must be allocat

  11. Characterizing Facesheet/Core Disbonding in Honeycomb Core Sandwich Structure

    Science.gov (United States)

    Rinker, Martin; Ratcliffe, James G.; Adams, Daniel O.; Krueger, Ronald

    2013-01-01

    Results are presented from an experimental investigation into facesheet core disbonding in carbon fiber reinforced plastic/Nomex honeycomb sandwich structures using a Single Cantilever Beam test. Specimens with three, six and twelve-ply facesheets were tested. Specimens with different honeycomb cores consisting of four different cell sizes were also tested, in addition to specimens with three different widths. Three different data reduction methods were employed for computing apparent fracture toughness values from the test data, namely an area method, a compliance calibration technique and a modified beam theory method. The compliance calibration and modified beam theory approaches yielded comparable apparent fracture toughness values, which were generally lower than those computed using the area method. Disbonding in the three-ply facesheet specimens took place at the facesheet/core interface and yielded the lowest apparent fracture toughness values. Disbonding in the six and twelve-ply facesheet specimens took place within the core, near to the facesheet/core interface. Specimen width was not found to have a significant effect on apparent fracture toughness. The amount of scatter in the apparent fracture toughness data was found to increase with honeycomb core cell size.

  12. Needle core biopsy for breast lesions: An audit of 467 needle core biopsies

    Directory of Open Access Journals (Sweden)

    Selvi Radhakrishna

    2013-01-01

    Full Text Available Background: Breast cancer is the commonest cancer among women in urban India. Triple assessment includes clinical, radiological and cytological assessment of breast lesions. Guided core needle biopsy has replaced fine needle aspiration cytology in most of the western countries. In resource poor countries FNAC is still a very valuable and cost effective method to diagnose breast lesions. Pitfalls include increased rates of non diagnostic smears, and inadequate smears. Further procedures may be required and this increases the cost, anxiety and delay in diagnosis. Aims: The aim of this study is to analyze the concordance of radiological and histopathology findings in BI-RADS category 3,4,5 lesions following a core biopsy. Materials and Methods: Data was retrospectively collected from consecutive symptomatic and opportunistic screen detected patients with abnormalities who underwent ultrasound guided interventional procedures from Jan 2010 to Aug 2011. Symptomatic patients underwent clinical examination, mammogram and breast ultrasound. Women under 35 years of age had only breast ultrasound. Core biopsy was performed under ultrasound guidance or clinically by a breast surgeon/ radiologist for BI-RADS category 3,4,5 lesions. Statistical Methods: Chi square test was done to show the strength of association of imaging findings and histopathology results of core biopsy. Results: 437 patients were symptomatic and 30 patients had screen detected abnormalities. The positive predictive value for BI-RADS 5 lesions for malignancy is 93.25% and the negative predictive value of BI-RADS category 3 lesions for cancer is 98.4%. False negative diagnosis on core biopsy was 0.85%. We were able to defer surgery in 60% of the patients with a clear radiological and pathological benign diagnosis. Conclusion: The PPV and NPV for cancer is high with needle core biopsy in BI-RADS 3,4,5 lesions. Where there is no discordance between clinical, radiology and pathology findings

  13. Introduction to the Core Curriculum in GIS

    OpenAIRE

    2015-01-01

    This short narrative introduces the Core Curriculum in GIS and provides a historical overview of the Core Curriculum Project, including the later Core Curriculum in GIScience and Core Curriculum for Technical Programs. Appended to this description is an original pamphlet advertising the Core Curriculum in GIS.

  14. Discovering biological progression underlying microarray samples.

    Directory of Open Access Journals (Sweden)

    Peng Qiu

    2011-04-01

    Full Text Available In biological systems that undergo processes such as differentiation, a clear concept of progression exists. We present a novel computational approach, called Sample Progression Discovery (SPD, to discover patterns of biological progression underlying microarray gene expression data. SPD assumes that individual samples of a microarray dataset are related by an unknown biological process (i.e., differentiation, development, cell cycle, disease progression, and that each sample represents one unknown point along the progression of that process. SPD aims to organize the samples in a manner that reveals the underlying progression and to simultaneously identify subsets of genes that are responsible for that progression. We demonstrate the performance of SPD on a variety of microarray datasets that were generated by sampling a biological process at different points along its progression, without providing SPD any information of the underlying process. When applied to a cell cycle time series microarray dataset, SPD was not provided any prior knowledge of samples' time order or of which genes are cell-cycle regulated, yet SPD recovered the correct time order and identified many genes that have been associated with the cell cycle. When applied to B-cell differentiation data, SPD recovered the correct order of stages of normal B-cell differentiation and the linkage between preB-ALL tumor cells with their cell origin preB. When applied to mouse embryonic stem cell differentiation data, SPD uncovered a landscape of ESC differentiation into various lineages and genes that represent both generic and lineage specific processes. When applied to a prostate cancer microarray dataset, SPD identified gene modules that reflect a progression consistent with disease stages. SPD may be best viewed as a novel tool for synthesizing biological hypotheses because it provides a likely biological progression underlying a microarray dataset and, perhaps more importantly, the

  15. Scalable Out-of-Core Solvers on Xeon Phi Cluster

    Energy Technology Data Exchange (ETDEWEB)

    D' Azevedo, Ed F [ORNL; Chan, Ki Shing [Chinese University of Hong Kong (CUHK); Su, Shiquan [Center for Computational Materials Science; Wong, Kwai [ORNL

    2015-01-01

    This paper documents the implementation of a distributive out-of-core (OOC) solver for performing LU and Cholesky factorizations of a large dense matrix on clusters of many-core programmable co-processors. The out-of- core algorithm combines both the left-looking and right-looking schemes aimed to minimize the movement of data between the CPU host and the co-processor, optimizing data locality as well as computing throughput. The OOC solver is built to align with the format of the ScaLAPACK software library, making it readily portable to any existing codes using ScaLAPACK. A runtime analysis conducted on Beacon (an Intel Xeon plus Intel Xeon Phi cluster which composed of 48 nodes of multi-core CPU and MIC) at the Na- tional Institute for Computational Sciences is presented. Comparison of the performance on the Intel Xeon Phi and GPU clusters are also provided.

  16. Implicit Unstructured Computational Aerodynamics on Many-Integrated Core Architecture

    KAUST Repository

    Al Farhan, Mohammed A.

    2014-05-04

    This research aims to understand the performance of PETSc-FUN3D, a fully nonlinear implicit unstructured grid incompressible or compressible Euler code with origins at NASA and the U.S. DOE, on many-integrated core architecture and how a hybridprogramming paradigm (MPI+OpenMP) can exploit Intel Xeon Phi hardware with upwards of 60 cores per node and 4 threads per core. For the current contribution, we focus on strong scaling with many-integrated core hardware. In most implicit PDE-based codes, while the linear algebraic kernel is limited by the bottleneck of memory bandwidth, the flux kernel arising in control volume discretization of the conservation law residuals and the preconditioner for the Jacobian exploits the Phi hardware well.

  17. Progress in biomaterials

    National Research Council Canada - National Science Library

    2012-01-01

    "Progress in Biomaterials is a multidisciplinary, English-language publication of original contributions and reviews concerning studies of the preparation, performance and evaluation of biomaterial...

  18. Natalizumab in progressive MS

    DEFF Research Database (Denmark)

    Romme Christensen, Jeppe; Ratzer, Rikke; Börnsen, Lars;

    2014-01-01

    OBJECTIVE: Natalizumab inhibits the migration of systemic immune cells to the CNS and may be beneficial in progressive multiple sclerosis (MS). The objective of the study was to examine the effects of natalizumab in progressive MS. METHODS: In an open-label phase 2A study, 24 patients with progre......OBJECTIVE: Natalizumab inhibits the migration of systemic immune cells to the CNS and may be beneficial in progressive multiple sclerosis (MS). The objective of the study was to examine the effects of natalizumab in progressive MS. METHODS: In an open-label phase 2A study, 24 patients...

  19. [Research progress on wetland ecotourism].

    Science.gov (United States)

    Wang, Li-Long; Lu, Lin

    2009-06-01

    Wetland is rich in biodiversity and cultural diversity, possessing higher tourism value and environmental education and community participation functions. Wetland ecotourism reflects the sustainable development of tourism economy and wetland protection, having received great concern from governments and scholars at home and abroad. This paper summarized the related theories and practices, discussed the research advances in wetland ecotourism from the aspects of significance, progress, contents, methods and results, and pointed out the important research fields in the future, aimed to accelerate the development of wetland ecotourism research and to provide reference about the resources exploitation, environment protection, and scientific administration of wetland and related scenic areas.

  20. The AIMS65 Score Is a Useful Predictor of Mortality in Patients with Nonvariceal Upper Gastrointestinal Bleeding: Urgent Endoscopy in Patients with High AIMS65 Scores.

    Science.gov (United States)

    Park, Sun Wook; Song, Young Wook; Tak, Dae Hyun; Ahn, Byung Moo; Kang, Sun Hyung; Moon, Hee Seok; Sung, Jae Kyu; Jeong, Hyun Yong

    2015-11-01

    To validate the AIMS65 score for predicting mortality of patients with nonvariceal upper gastrointestinal bleeding and to evaluate the effectiveness of urgent (Nonvariceal, upper gastrointestinal bleeding was assessed by using the AIM65 and Rockall scores. Scores for mortality were assessed by calculating the area under the receiver-operating characteristic curve (AUROC). Patients with high AIMS65 scores (≥2) were allocated to either the urgent or non-urgent endoscopic procedure group. In-hospital mortality, success of endoscopic procedure, recurrence of bleeding, admission period, and dose of transfusion were compared between groups. A total of 634 patients were analyzed. The AIMS65 score successfully predicted mortality (AUROC=0.943; 95% confidence interval [CI], 0.876 to 0.99) and was superior to the Rockall score (AUROC=0.856; 95% CI, 0.743 to 0.969) in predicting mortality. The group with high AIMS65 score included 200 patients. The urgent endoscopic procedure group had reduced hospitalization periods (pnonvariceal upper gastrointestinal bleeding. Urgent endoscopic procedures in patients with high scores may be related to reduced hospitalization periods.

  1. Core ethical issues of clinical nursing supervision.

    Science.gov (United States)

    Berggren, Ingela; Barbosa da Silva, António; Severinsson, Elisabeth

    2005-03-01

    Clinical nursing supervision enables supervisees to reflect on ethically difficult caring situations, thereby strengthening their professional identity, integrating nursing theory and practice, and leading to the development of ethical competence. The aim of this study was to develop an understanding of the core ethical issues of clinical nursing supervision, using previous research as well as philosophical analysis of the theories of three moral philosophers: Harald Ofstad, Richard Hare and Carol Gilligan. The ultimate aim of this study was to develop a general model for ethical decision-making and to establish its relevance for clinical nursing supervision. The findings highlight four important values for the development of a basis for ethical decision-making. These values are caring, dignity, responsibility and virtue.

  2. Progression of Liver Disease

    Science.gov (United States)

    ... 2014 Calendar of Events In The News Academic Debates Recipe of the Month Core Programs Patient Profile ... or if you should undergo any tests or vaccinations. Web Toolbar by Wibiya Page updated: December 6th, ...

  3. Assessing Core Competencies

    Science.gov (United States)

    Narayanan, M.

    2004-12-01

    Catherine Palomba and Trudy Banta offer the following definition of assessment, adapted from one provided by Marches in 1987. Assessment in the systematic collection, review, and use of information about educational programs undertaken for the purpose of improving student learning and development. (Palomba and Banta 1999). It is widely recognized that sophisticated computing technologies are becoming a key element in today's classroom instructional techniques. Regardless, the Professor must be held responsible for creating an instructional environment in which the technology actually supplements learning outcomes of the students. Almost all academic disciplines have found a niche for computer-based instruction in their respective professional domain. In many cases, it is viewed as an essential and integral part of the educational process. Educational institutions are committing substantial resources to the establishment of dedicated technology-based laboratories, so that they will be able to accommodate and fulfill students' desire to master certain of these specific skills. This type of technology-based instruction may raise some fundamental questions about the core competencies of the student learner. Some of the most important questions are : 1. Is the utilization of these fast high-powered computers and user-friendly software programs creating a totally non-challenging instructional environment for the student learner ? 2. Can technology itself all too easily overshadow the learning outcomes intended ? 3. Are the educational institutions simply training students how to use technology rather than educating them in the appropriate field ? 4. Are we still teaching content-driven courses and analysis oriented subject matter ? 5. Are these sophisticated modern era technologies contributing to a decline in the Critical Thinking Capabilities of the 21st century technology-savvy students ? The author tries to focus on technology as a tool and not on the technology

  4. Measuring the extent of convective cores in low-mass stars using Kepler data: towards a calibration of core overshooting

    CERN Document Server

    Deheuvels, S; Aguirre, V Silva; Ballot, J; Michel, E; Cunha, M S; Lebreton, Y; Appourchaux, T

    2016-01-01

    Our poor understanding of the boundaries of convective cores generates large uncertainties on the extent of these cores and thus on stellar ages. Our aim is to use asteroseismology to consistently measure the extent of convective cores in a sample of main-sequence stars whose masses lie around the mass-limit for having a convective core. We first test and validate a seismic diagnostic that was proposed to probe in a model-dependent way the extent of convective cores using the so-called $r_{010}$ ratios, which are built with $l=0$ and $l=1$ modes. We apply this procedure to 24 low-mass stars chosen among Kepler targets to optimize the efficiency of this diagnostic. For this purpose, we compute grids of stellar models with both the CESAM2k and MESA evolution codes, where the extensions of convective cores are modeled either by an instantaneous mixing or as a diffusion process. Among the selected targets, we are able to unambiguously detect convective cores in eight stars and we obtain seismic measurements of th...

  5. Viral Evolution Core | FNLCR Staging

    Science.gov (United States)

    Brandon F. Keele, Ph.D. PI/Senior Principal Investigator, Retroviral Evolution Section Head, Viral Evolution Core Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research Frederick, MD 21702-1201 Tel: 301-846-173

  6. Lunar Core Drive Tubes Summary

    Data.gov (United States)

    National Aeronautics and Space Administration — Contains a brief summary and high resolution imagery from various lunar rock and core drive tubes collected from the Apollo and Luna missions to the moon.

  7. Exploring the Environments of Core-Collapse Supernovae

    Science.gov (United States)

    Habergham, Stacey; Anderson, Joe; James, Phil; Lyman, Joe

    2015-06-01

    Despite years of intense research on the exact nature of core-collapse supernovae (CCSNe), much uncertainty still surrounds the progenitor systems of these explosions. Only the most common subtype (SNIIP) has a known origin, thanks to numerous direct observations of the progenitor stars. However, direct detections are limited by the frequency of nearby events. This led to the analysis of the host galaxies, in the assumption that trends in large samples of events could give indications of the progenitor systems of SNe. Indeed it was these investigations which concluded that CCSNe must originate from young, massive stars, due to their sole presence in star-forming galaxies. Over the past 20 years a new field of research has aimed to straddle these two techniques, looking at the local environment of the progenitor within the host galaxy. This technique is effective out to a larger distance than direct detections ( 80 Mpc), but is limited by the requirement to be able to resolve the regions at the location of, or close to the SN coordinates. These regions are significantly smaller than the entire galaxy but may still contain thousands of stars, if not more. The compromise here is between gathering large enough samples for meaningful statistical analysis, and gathering information on the environment local to the SN. This technique allows statistical constraints to be made on progenitor properties such as mass and metallicity, and this review talk will highlight the progress that has been made in this field, including; differences in the explosion sites of SNe types II and Ibc, the fact that SNe Ic are significantly more associated with host star formation than SNe Ib, and that the interacting SNe IIn do not explode in regions containing the most massive stars.

  8. Synthetic observations of first hydrostatic cores in collapsing low-mass dense cores. I. Spectral energy distributions and evolutionary sequence

    CERN Document Server

    Commercon, Benoit; Dullemond, Cornelis P; Henning, Thomas

    2012-01-01

    The low-mass star formation evolutionary sequence is relatively well-defined both from observations and theoretical considerations. The first hydrostatic core is the first protostellar equilibrium object that is formed during the star formation process. Using state-of-the-art radiation-magneto-hydrodynamic 3D adaptive mesh refinement calculations, we aim to provide predictions for the dust continuum emission from first hydrostatic cores. We investigate the collapse and the fragmentation of magnetized one solar mass prestellar dense cores and the formation and evolution of first hydrostatic cores using the RAMSES code. We use three different magnetization levels for the initial conditions, which cover a large variety of early evolutionary morphology, e.g., the formation of a disk or a pseudo-disk, outflow launching, and fragmentation. We post-process the dynamical calculations using the 3D radiative transfer code RADMC-3D. We compute spectral energy distributions and usual evolutionary stage indicators such as...

  9. Viscosity of the earth's core.

    Science.gov (United States)

    Gans, R. F.

    1972-01-01

    Calculation of the viscosity of the core at the boundary of the inner and outer core. It is assumed that this boundary is a melting transition and the viscosity limits of the Andrade (1934,1952) hypothesis (3.7 to 18.5 cp) are adopted. The corresponding kinematic viscosities are such that the precessional system explored by Malkus (1968) would be unstable. Whether it would be sufficiently unstable to overcome a severely subadiabatic temperature gradient cannot be determined.

  10. Nanoporous polymer liquid core waveguides

    DEFF Research Database (Denmark)

    Gopalakrishnan, Nimi; Christiansen, Mads Brøkner; Ndoni, Sokol

    2010-01-01

    We demonstrate liquid core waveguides defined by UV to enable selective water infiltration in nanoporous polymers, creating an effective refractive index shift Δn=0.13. The mode confinement and propagation loss in these waveguides are presented.......We demonstrate liquid core waveguides defined by UV to enable selective water infiltration in nanoporous polymers, creating an effective refractive index shift Δn=0.13. The mode confinement and propagation loss in these waveguides are presented....

  11. Radial molecular abundances and gas cooling in starless cores

    CERN Document Server

    Sipilä, O

    2012-01-01

    Aims: We aim to simulate radial profiles of molecular abundances and the gas temperature in cold and heavily shielded starless cores by combining chemical and radiative transfer models. Methods: A determination of the dust temperature in a modified Bonnor-Ebert sphere is used to calculate initial radial molecular abundance profiles. The abundances of selected cooling molecules corresponding to two different core ages are then extracted to determine the gas temperature at two time steps. The calculation is repeated in an iterative process yielding molecular abundances consistent with the gas temperature. Line emission profiles for selected substances are calculated using simulated abundance profiles. Results: The gas temperature is a function of time; the gas heats up as the core gets older because the cooling molecules are depleted onto grain surfaces. The contributions of the various cooling molecules to the total cooling power change with time. Radial chemical abundance profiles are non-trivial: different s...

  12. Recent progress on high-speed optical transmission

    Directory of Open Access Journals (Sweden)

    Jianjun Yu

    2016-05-01

    Full Text Available The recently reported high spectral efficiency (SE and high-baud-rate signal transmission are all based on digital coherent optical communications and digital signal processing (DSP. DSP simplifies the reception of advanced modulation formats and also enables the major electrical and optical impairments to be processed and compensated in the digital domain, at the transmitter or receiver side. In this paper, we summarize the research progress on high-speed signal generation and detection and also show the progress on DSP for high-speed signal detection. We also report the latest progress on multi-core and multi-mode multiplexing.

  13. Aiming for the stomach and hitting the heart: dissociable triggers and sources for disgust reactions.

    Science.gov (United States)

    Shenhav, Amitai; Mendes, Wendy Berry

    2014-04-01

    Disgust reactions can be elicited using stimuli that engender orogastric rejection (e.g., pus and vomit; core disgust stimuli) but also using images of bloody injuries or medical procedures (e.g., surgeries; blood [body] boundary violation [B-BV] disgust stimuli). These two types of disgust reaction are presumed to be connected by a common evolutionary function of avoiding either food- or blood-borne contaminants. However, reactions to bloody injuries are typically conflated with reactions to the potential pain being experienced by the victim. This may explain why the two forms of "disgust", although similarly communicated (through self-report and facial expressions), evince different patterns of physiological reactivity. Therefore, we tested whether the communicative similarities and physiological dissimilarities would hold when markers of potential contamination in the latter category are removed, leaving only painful injuries that lack blood or explicit body-envelope violations. Participants viewed films that depicted imagery associated with (a) core disgust, (b) painful injuries, or (c) neutral scenes while we measured facial, cardiovascular, and gastric reactivity. Whereas communicative measures (self-report and facial muscles) suggested that participants experienced increased disgust for core disgust and painful injuries, peripheral physiology dissociated the two: core disgust decreased normal gastric activity and painful-injury disgust decelerated heart rate and increased heart rate variability. These findings suggest that expressions of disgust toward bodily injuries may reflect a fundamentally different affective response than those evoked by core disgust and that this (cardiovascularly mediated) response may in fact be more closely tied to pain perceptions (or empathy) rather than contaminant-laden stimuli.

  14. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  15. Integral Fast Reactor Program annual progress report, FY 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R D.

  16. Remedial Sheets for Progress Checks, Segments 1-14.

    Science.gov (United States)

    New York Inst. of Tech., Old Westbury.

    The first part of the Self-Paced Physics Course remediation materials is presented for U. S. Naval Academy students who miss core problems on the progress check. The total of 78 problems is incorporated in this volume to match study segments 1 through 14. Each remedial sheet is composed of a statement of the missed problem and references to…

  17. Integral Fast Reactor Program annual progress report, FY 1994

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, J.J.

    1994-12-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1994. Technical accomplishments are presented in the following areas of the IFR technology development activities: metal fuel performance; pyroprocess development; safety experiments and analyses; core design development; fuel cycle demonstration; and LMR technology R&D.

  18. Integral Fast Reactor Program. Annual progress report, FY 1992

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1993-06-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1992. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

  19. Integral Fast Reactor Program. Annual progress report, FY 1993

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

    1994-10-01

    This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1993. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R and D.

  20. [The core of solidarity].

    Science.gov (United States)

    Trappenburg, Margo J

    2013-01-01

    Dutch Journal of Medicine (NTVG) Lecture 2013: Organized solidarity in a welfare state is impersonal, restricted and based on enlightened self-interest. Critics of the welfare state argue that it is obsolete and we should aim for a society based on individual participation. They believe that people now prefer individualized care, that it is no longer possible to set boundaries and that too much altruism is required from those with higher incomes. In this year's NTvG lecture Margo Trappenburg contended that this criticism is unjust. Many people prefer professional care to care from the family or from volunteers and it could be possible to set boundaries again: recent developments within the medical profession are hopeful. And although the more highly educated make a greater financial contribution to the welfare state, those with a lower level of education show more, and more frequent, active solidarity. There is insufficient reason to abolish the welfare state and replace it with a society of greater individual participation.

  1. First-aid with warm water delays burn progression and increases skin survival.

    Science.gov (United States)

    Tobalem, M; Harder, Y; Tschanz, E; Speidel, V; Pittet-Cuénod, B; Wettstein, R

    2013-02-01

    First aid treatment for thermal injuries with cold water removes heat and decreases inflammation. However, perfusion in the ischemic zone surrounding the coagulated core can be compromised by cold-induced vasoconstriction and favor burn progression. The aim of this study is to evaluate the effect of local warming on burn progression in the rat comb burn model. 24 male Wistar rats were randomly assigned to either no treatment (control) or application of cold (17 °C) or warm (37 °C) water applied for 20 min. Evolution of burn depth, interspace necrosis, and microcirculatory perfusion were assessed with histology, planimetry, respectively with Laser Doppler flowmetry after 1 h, as well as 1, 4, and 7 days. Consistent conversion from a superficial to a deep dermal burn within 24 h was obtained in control animals. Warm and cold water significantly delayed burn depth progression, however after 4 days the burn depth was similar in all groups. Interspace necrosis was significantly reduced by warm water treatment (62±4% vs. 69±5% (cold water) and 82±3% (control); pcold water and 80±2% for control, pwater provided an additional benefit by improving the microcirculatory perfusion, which translated into increased tissue survival. Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  2. Psychological Analysis on the Aim of Penalty%刑罚目的的心理学分析

    Institute of Scientific and Technical Information of China (English)

    周永坤; 李振东

    2012-01-01

    刑罚目的在刑罚理论中居于核心地位,它对于刑罚的创制与适用有着直接的指导意义。从心理学角度探究刑罚目的,将有利于完善国家立法和司法。法律情境中存在3种心理状态:公正、上位公正和下位公正;基于个人的刑罚目的是实现以公正为标准的个体心理均衡;基于社会的刑罚目的是实现以不平等的公正为标准的社会心理均衡;司法理念和刑罚制度要随着公正状态的变迁而变迁;社会心理获得有效均衡的途径是开启大众理性,降低社会交流的交易成本。%The aim of penalty occupies the core position in the penalty theory, and it has directive meaning for the punishment creating and applying. Studying the aim of penalty in psychological terms will be helpful to the perfection of national legislation and judiciary. There are three types of psychological state in legal circumstances: justice, upper justice and lower justice. The aim of individual-based penalty is to realize individual psychological equilibrium with justice as a standard; the aim of societybased penalty is to realize social psychological equilibrium taking justice as a standard. The judicial philosophy and penalty system should vary with the state of justice. The effective way to obtain social psychological equilibrium is to open the public sense, reduce the transaction cost of social exchange.

  3. Progression i musikundervisningen

    DEFF Research Database (Denmark)

    Dahlbæk, Annelise

    Hvad er progression? ; Musikalitetsbegrebet ; Fælles mål for musik ; Modeller som redskab ; Stemmen : sang ; Sammenspil ; Dans og bevægelse ; Lytning......Hvad er progression? ; Musikalitetsbegrebet ; Fælles mål for musik ; Modeller som redskab ; Stemmen : sang ; Sammenspil ; Dans og bevægelse ; Lytning...

  4. White matter lesion progression

    DEFF Research Database (Denmark)

    Hofer, Edith; Cavalieri, Margherita; Bis, Joshua C;

    2015-01-01

    BACKGROUND AND PURPOSE: White matter lesion (WML) progression on magnetic resonance imaging is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here, we estimated heritability of WML progression, and sought common genetic variants...

  5. Responsible Canadian energy progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The Canadian Association of Petroleum Producers (CAPP) represents oil and gas companies throughout Canada; its members produce over 90% of Canada's natural gas and crude oil output. The aim of the Association is to improve the economics of the Canadian upstream petroleum sector in an environmentally and socially responsible way. The aim of this Responsible Canadian Energy report is to present the performance data of CAPP's members for the year 2009. Data, trends, and performance analyses are provided throughout the document. This analysis makes it possible to determine where progress has been made and where performance improvement is necessary. It also presents success stories and best practices so that other companies can learn from them how to improve their own performance. This paper provides useful information on the performance of the upstream petroleum industry in Canada and highlights where the focus should be for further improvement in its performance.

  6. Interventions to Reduce Myopia Progression in Children.

    Science.gov (United States)

    Tay, Su Ann; Farzavandi, Sonal; Tan, Donald

    2017-03-01

    Efforts to reduce the progression of myopia in childhood are on the rise, due to an increasing incidence of myopia worldwide and its associated sight-threatening complications. Interventions are aimed at reducing myopia in childhood and include environmental considerations, spectacles, contact lenses, and pharmacological agents. We reviewed recent literature with interventions aimed at reducing myopia progression in children and found that a number of interventions were significant in reducing the progression of myopia. Of these interventions, atropine showed the largest dose-related effect on myopia progression control. Although higher doses are associated with side effects of pupil dilatation, loss of accommodation, near vision blur, and rebound phenomenon, low-dose atropine has also been shown to provide effective myopia control with minimal side effects and rebound. To a lesser degree, bifocal soft contact lenses have also been shown to be effective in reducing the progression of myopia, though compliance is an issue. Similarly, orthokeratology lenses have also been shown to be effective in reducing axial length elongation and myopia progression, though long-term data on its rebound effects are unavailable.

  7. Cloud-Based Collaborative Writing and the Common Core Standards

    Science.gov (United States)

    Yim, Soobin; Warschauer, Mark; Zheng, Binbin; Lawrence, Joshua F.

    2014-01-01

    The Common Core State Standards emphasize the integration of technology skills into English Language Arts (ELA) instruction, recognizing the demand for technology-based literacy skills to be college- and career- ready. This study aims to examine how collaborative cloud-based writing is used in in a Colorado school district, where one-to-one…

  8. Emotion Dysregulation and the Core Features of Autism Spectrum Disorder

    Science.gov (United States)

    Samson, Andrea C.; Phillips, Jennifer M.; Parker, Karen J.; Shah, Shweta; Gross, James J.; Hardan, Antonio Y.

    2014-01-01

    The aim of this study was to examine the relationship between emotion dysregulation and the core features of Autism Spectrum Disorder (ASD), which include social/communication deficits, restricted/repetitive behaviors, and sensory abnormalities. An 18-item Emotion Dysregulation Index was developed on the basis of expert ratings of the Child…

  9. Cloud-Based Collaborative Writing and the Common Core Standards

    Science.gov (United States)

    Yim, Soobin; Warschauer, Mark; Zheng, Binbin; Lawrence, Joshua F.

    2014-01-01

    The Common Core State Standards emphasize the integration of technology skills into English Language Arts (ELA) instruction, recognizing the demand for technology-based literacy skills to be college- and career- ready. This study aims to examine how collaborative cloud-based writing is used in in a Colorado school district, where one-to-one…

  10. Multi-Core BDD Operations for Symbolic Reachability

    NARCIS (Netherlands)

    van Dijk, Tom; Laarman, Alfons; van de Pol, Jan Cornelis; Heljanko, K.; Knottenbelt, W.J.

    2012-01-01

    This paper presents scalable parallel BDD operations for modern multi-core hardware. We aim at increasing the performance of reachability analysis in the context of model checking. Existing approaches focus on performing multiple independent BDD operations rather than parallelizing the BDD

  11. Appeals in television advertising: A content analysis of commercials aimed at children and teenagers

    OpenAIRE

    Buijzen, M.A.; Valkenburg, P.M.

    2002-01-01

    A content analysis of 601 commercials was conducted in order to identify the appeals that characterize commercials aimed at children and teenagers. Our findings demonstrated that the use of appeals (a) showed strong age differences and (b) was highly gender-role stereotyped, particularly in commercials aimed at children. The most typical appeals in commercials aimed at male children were action-adventure, sports, and play, whereas commercials aimed at female children emphasized nurturing, phy...

  12. Cell "circadian" cycle: new role for mammalian core clock genes.

    Science.gov (United States)

    Borgs, Laurence; Beukelaers, Pierre; Vandenbosch, Renaud; Belachew, Shibeshih; Nguyen, Laurent; Malgrange, Brigitte

    2009-03-15

    In mammals, 24 hours rhythms are organized as a biochemical network of molecular clocks that are operative in all tissues, with the master clock residing in the hypothalamic suprachiasmatic nucleus (SCN). The core pacemakers of these clocks consist of auto-regulatory transcriptional/post-transcriptional feedback loops. Several lines of evidence suggest the existence of a crosstalk between molecules that are responsible for the generation of circadian rhythms and molecules that control the cell cycle progression. In addition, highly specialized cell cycle checkpoints involved in DNA repair after damage seem also, at least in part, mediated by clock proteins. Recent studies have also highlighted a putative connection between clock protein dysfunction and cancer progression. This review discusses the intimate relation that exists between cell cycle progression and components of the circadian machinery.

  13. Coupled-cluster methods for core-hole dynamics

    Science.gov (United States)

    Picon, Antonio; Cheng, Lan; Hammond, Jeff R.; Stanton, John F.; Southworth, Stephen H.

    2014-05-01

    Coupled cluster (CC) is a powerful numerical method used in quantum chemistry in order to take into account electron correlation with high accuracy and size consistency. In the CC framework, excited, ionized, and electron-attached states can be described by the equation of motion (EOM) CC technique. However, bringing CC methods to describe molecular dynamics induced by x rays is challenging. X rays have the special feature of interacting with core-shell electrons that are close to the nucleus. Core-shell electrons can be ionized or excited to a valence shell, leaving a core-hole that will decay very fast (e.g. 2.4 fs for K-shell of Ne) by emitting photons (fluorescence process) or electrons (Auger process). Both processes are a clear manifestation of a many-body effect, involving electrons in the continuum in the case of Auger processes. We review our progress of developing EOM-CC methods for core-hole dynamics. Results of the calculations will be compared with measurements on core-hole decays in atomic Xe and molecular XeF2. This work is funded by the Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy, under Contract No. DE-AC02-06CH11357.

  14. 78 FR 69885 - AIM Growth Series (Invesco Growth Series), et al.; Notice of Application

    Science.gov (United States)

    2013-11-21

    ... COMMISSION AIM Growth Series (Invesco Growth Series), et al.; Notice of Application November 15, 2013. AGENCY... approval and would grant relief from certain disclosure requirements. APPLICANTS: AIM Growth Series (Invesco Growth Series) and AIM Investment Funds (Invesco Investment Funds) (each, a ``Trust''), and...

  15. DMPD: Fifty years of interferon research: aiming at a moving target. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16979566 Fifty years of interferon research: aiming at a moving target. Vilcek J. I...mmunity. 2006 Sep;25(3):343-8. (.png) (.svg) (.html) (.csml) Show Fifty years of interferon research: aiming... at a moving target. PubmedID 16979566 Title Fifty years of interferon research: aiming at a moving target.

  16. Important treatment aims at the end of life: a nationwide study among GPs.

    NARCIS (Netherlands)

    Claessen, S.J.J.; Echteld, M.A.; Francke, A.L.; Block, L. van den; Donker, G.A.; Deliens, L.

    2012-01-01

    Background: Little is known about treatment aims during the last 3 months of life. Aim: To investigate important treatment aims in the last 3 months of patients' lives in cases of on-sudden death. Design and setting: Mortality follow-back study in the Netherlands. Method: data were collected retrosp

  17. Crystallization in Earth's Core after High-Temperature Core Formation

    Science.gov (United States)

    Hirose, K.; Morard, G.; Hernlund, J. W.; Helffrich, G. R.; Ozawa, H.

    2015-12-01

    Recent core formation models based on the metal-silicate partitioning of siderophile elements suggest that the Earth's core was formed by metal segregation at high pressure and high temperature in a deep magma ocean. It is also thought that the simultaneous solubility of silicon and oxygen in liquid iron are strongly enhanced at high pressure and high temperature, such that at the end of accretion the core was rich in both silicon and oxygen. Here we performed crystallization experiments on the Fe-Si binary and Fe-Si-O ternary systems up to core pressure in a laser-heated diamond-anvil cell. The starting material for the latter was a homogeneous mixture of fine-grain Fe-Si and SiO2 (sustain without extreme degrees of secular cooling. However, even for modest degrees of joint Si-O incorporation into the early core, the buoyancy released by crystallization of SiO2 is sufficient to overcome thermal stratification and sustain the geodynamo.

  18. Progression from acute to chronic pancreatitis: prognostic factors, mortality, and natural course

    DEFF Research Database (Denmark)

    Nøjgaard, Camilla; Becker, Ulrik; Matzen, Peter

    2011-01-01

    Knowledge of the natural course of acute pancreatitis (AP) and risk of progression to chronic pancreatitis (CP) is limited. The aims were to describe: (1) the incidence of progression from AP to CP, (2) prognostic factors for progression, and (3) the natural course and mortality of progressive AP....

  19. Comments on evolvement into aeronautical information management(AIM)%浅析向航空情报管理(AIM)发展

    Institute of Scientific and Technical Information of China (English)

    王丹阳

    2010-01-01

    @@ 2010年8月,国际民航组织(ICAO)的全球航空情报管理(AIM)大会将在北京召开.ICAO认为,为了满足全球空中交通管理运行概念的新要求,航空情报服务必须过渡到航空情报管理这一更广泛的概念.

  20. Core formation in silicate bodies

    Science.gov (United States)

    Nimmo, F.; O'Brien, D. P.; Kleine, T.

    2008-12-01

    Differentiation of a body into a metallic core and silicate mantle occurs most efficiently if temperatures are high enough to allow at least the metal to melt [1], and is enhanced if matrix deformation occurs [2]. Elevated temperatures may occur due to either decay of short-lived radio-isotopes, or gravitational energy release during accretion [3]. For bodies smaller than the Moon, core formation happens primarily due to radioactive decay. The Hf-W isotopic system may be used to date core formation; cores in some iron meteorites and the eucrite parent body (probably Vesta) formed within 1 My and 1-4~My of solar system formation, respectively [4]. These formation times are early enough to ensure widespread melting and differentiation by 26Al decay. Incorporation of Fe60 into the core, together with rapid early mantle solidification and cooling, may have driven early dynamo activity on some bodies [5]. Iron meteorites are typically depleted in sulphur relative to chondrites, for unknown reasons [6]. This depletion contrasts with the apparently higher sulphur contents of cores in larger planetary bodies, such as Mars [7], and also has a significant effect on the timing of core solidification. For bodies of Moon-size and larger, gravitational energy released during accretion is probably the primary cause of core formation [3]. The final stages of accretion involve large, stochastic collisions [8] between objects which are already differentiated. During each collision, the metallic cores of the colliding objects merge on timescales of a few hours [9]. Each collision will reset the Hf-W isotopic signature of both mantle and core, depending on the degree to which the impactor core re-equilibrates with the mantle of the target [10]. The re-equilibration efficiency depends mainly on the degree to which the impactor emulsifies [11], which is very uncertain. Results from N-body simulations [8,12] suggest that significant degrees of re- equilibration are required [4,10]. Re

  1. Viscosity of Earth's Outer Core

    CERN Document Server

    Smylie, D E

    2007-01-01

    A viscosity profile across the entire fluid outer core is found by interpolating between measured boundary values, using a differential form of the Arrhenius law governing pressure and temperature dependence. The discovery that both the retrograde and prograde free core nutations are in free decay (Palmer and Smylie, 2005) allows direct measures of viscosity at the top of the outer core, while the reduction in the rotational splitting of the two equatorial translational modes of the inner core allows it to be measured at the bottom. We find 2,371 plus/minus 1,530 Pa.s at the top and 1.247 plus/minus 0.035 x 10^11 Pa.s at the bottom. Following Brazhkin (1998) and Brazhkin and Lyapin (2000) who get 10^2 Pa.s at the top, 10^11 Pa.s at the bottom, by an Arrhenius extrapolation of laboratory experiments, we use a differential form of the Arrhenius law to interpolate along the melting temperature curve to find a viscosity profile across the outer core. We find the variation to be closely log-linear between the meas...

  2. Core vocabulary of young children with Down syndrome.

    Science.gov (United States)

    Deckers, Stijn R J M; Van Zaalen, Yvonne; Van Balkom, Hans; Verhoeven, Ludo

    2017-06-01

    The aim of this study was to develop a core vocabulary list for young children with intellectual disabilities between 2 and 7 years of age because data from this population are lacking in core vocabulary literature. Children with Down syndrome are considered one of the most valid reference groups for researching developmental patterns in children with intellectual disabilities; therefore, spontaneous language samples of 30 Dutch children with Down syndrome were collected during three different activities with multiple communication partners (free play with parents, lunch- or snack-time at home or at school, and speech therapy sessions). Of these children, 19 used multimodal communication, primarily manual signs and speech. Functional word use in both modalities was transcribed. The 50 most frequently used core words accounted for 67.2% of total word use; 16 words comprised core vocabulary, based on commonality. These data are consistent with similar studies related to the core vocabularies of preschoolers and toddlers with typical development, although the number of nouns present on the core vocabulary list was higher for the children in the present study. This finding can be explained by manual sign use of the children with Down syndrome and is reflective of their expressive vocabulary ages.

  3. Prestellar and protostellar cores in Ori B9

    CERN Document Server

    Miettinen, O; Haikala, L K; Kainulainen, J; Johansson, L E B

    2009-01-01

    The aims of this study are to determine the properties and spatial distribution of dense cores in Ori B9, and to estimate their ages and dynamical timescales. The cloud was mapped in the 870 micron continuum with APEX/LABOCA, and selected positions were observed in the lines of N2H+ and N2D+ using IRAM-30m. These were used together with our previous H2D+ observations. Moreover, archival FIR Spitzer/MIPS maps were combined with the LABOCA map to distinguish between pre- and protostellar cores, and to estimate the evolutionary stages of protostars. Twelve dense cores were detected at 870 micron in the Ori B9 cloud. The submm cores constitute ~4% of the total mass of the Ori B9 region. There is an equal number of pre- and protostellar cores. Two of the submm sources, which we call SMM 3 and SMM 4, are previously unknown Class 0 candidates. We found a moderate degree of deuteration in N2H+ (0.03-0.04). There is, furthermore, evidence for N2H+ depletion in the core SMM 4. We derive a relatively high degree of ioni...

  4. Modelling line emission of deuterated H3+ from prestellar cores

    Science.gov (United States)

    Sipilä, O.; Hugo, E.; Harju, J.; Asvany, O.; Juvela, M.; Schlemmer, S.

    2010-01-01

    Context. The depletion of heavy elements in cold cores of interstellar molecular clouds can lead to a situation where deuterated forms of H3+ are the most useful spectroscopic probes of the physical conditions. Aims: The aim is to predict the observability of the rotational lines of H2D+ and D2H+ from prestellar cores. Methods: Recently derived rate coefficients for the H3+ + H2 isotopic system were applied to the “complete depletion” reaction scheme to calculate abundance profiles in hydrostatic core models. The ground-state lines of H2D+(o) (372 GHz) and D2H+(p) (692 GHz) arising from these cores were simulated. The excitation of the rotational levels of these molecules was approximated by using the state-to-state coefficients for collisions with H2. We also predicted line profiles from cores with a power-law density distribution advocated in some previous studies. Results: The new rate coefficients introduce some changes to the complete depletion model, but do not alter the general tendencies. One of the modifications with respect to the previous results is the increase of the D3+ abundance at the cost of other isotopologues. Furthermore, the present model predicts a lower H2D+ (o/p) ratio, and a slightly higher D2H+ (p/o) ratio in very cold, dense cores, as compared with previous modelling results. These nuclear spin ratios affect the detectability of the submm lines of H2D+(o) and D2H+(p). The previously detected H2D+ and D2H+ lines towards the core I16293E, and the H2D+ line observed towards Oph D can be reproduced using the present excitation model and the physical models suggested in the original papers.

  5. SMART core protection system design

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. K.; Park, H. Y.; Koo, I. S. [KAERI, Taejon (Korea, Republic of); Park, H. S.; Kim, J. S.; Son, C. H. [Samchang Enterprise Co., Ltd., Taejon (Korea, Republic of)

    2003-10-01

    SMART COre Protection System(SCOPS) is designed with real-tims Digital Signal Processor(DSP) board and Network Interface Card(NIC) board. SCOPS has a Control Rod POSition (CRPOS) software module while Core Protection Calculator System(CPCS) consists of Core Protection Calculators(CPCs) and Control Element Assembly(CEA) Calculators(CEACs) in the commercial nuclear plant. It's not necessary to have a independent cabinets for SCOPS because SCOPS is physically very small. Then SCOPS is designed to share the cabinets with Plant Protection System(PPS) of SMART. Therefor it's very easy to maintain the system because CRPOS module is used instead of the computer with operating system.

  6. Atmospheric Methane in Ice Cores

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The reconstruction of air trapped in ice cores provides us the most direct information about atmospheric CH4 variations in the past history. Ice core records from the "Three Poles (Antarctica, Greenland and Tibetan Plateau)" reveal the detailed fluctuations of atmospheric CH4 concentration with time and are allowed to quantify the CH4 differences among latitudes. These data are indispensably in the farther study of the relationship between greenhouse gases and climatic change, and of the past changes in terrestrial CH4 emissions. Ice cores reconstruction indicates that atmospheric CH4 concentration has increased quickly since industrialization, and the present day's level of atmospheric CH4 (1800 ppbv) is unprecedented during the past Glacial-Interglacial climate cycles.

  7. Distributed k-Core Decomposition

    CERN Document Server

    Montresor, Alberto; Miorandi, Daniele

    2011-01-01

    Among the novel metrics used to study the relative importance of nodes in complex networks, k-core decomposition has found a number of applications in areas as diverse as sociology, proteinomics, graph visualization, and distributed system analysis and design. This paper proposes new distributed algorithms for the computation of the k-core decomposition of a network, with the purpose of (i) enabling the run-time computation of k-cores in "live" distributed systems and (ii) allowing the decomposition, over a set of connected machines, of very large graphs, that cannot be hosted in a single machine. Lower bounds on the algorithms complexity are given, and an exhaustive experimental analysis on real-world graphs is provided.

  8. Core Competencies in Advanced Training: What Supervisors Say about Graduate Training

    Science.gov (United States)

    Nelson, Thorana S.; Graves, Todd

    2011-01-01

    In an attempt to identify needed mental health skills, many professional organizations have or are in the process of establishing core competency standards for their professions. The AAMFT identified 128 core competencies for the independent practice of MFT. The aim of this study was to learn the opinions of AAMFT Approved Supervisors as to how…

  9. Core Competencies in Advanced Training: What Supervisors Say about Graduate Training

    Science.gov (United States)

    Nelson, Thorana S.; Graves, Todd

    2011-01-01

    In an attempt to identify needed mental health skills, many professional organizations have or are in the process of establishing core competency standards for their professions. The AAMFT identified 128 core competencies for the independent practice of MFT. The aim of this study was to learn the opinions of AAMFT Approved Supervisors as to how…

  10. Effect of Core Training on 16 Year-Old Soccer Players

    Science.gov (United States)

    Afyon, Yakup Akif

    2014-01-01

    Core trainings have been widely used by trainers recently in order to improve performance of soccer players. In this context, the aim of this study is to examine the effect of core training on some motoric capabilities of 16 years old soccer players. Thirty certified soccer players who were 16 years old from B.B. Bodrumspor Club in 2013-2014…

  11. The "Bain Linguistique": A Core French Experiment at Churchill Alternative School, 1993-94. Final Report.

    Science.gov (United States)

    Wesche, Marjorie; MacFarlane, Alina; Peters, Martine

    This report describes an experimental intensive core French program for grades 5 and 6 at Churchill Alternative School in Ottawa (Canada). The aim was to improve the oral French skills of core French students by providing a period of intensive exposure to French and by increasing the total number of hours in French during one program year from 120…

  12. Progress in Seawater Desalination

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Scientists from the CAS Changchun Institute of Applied Chemistry have made significant progress in developing advanced expertise of seawater desalination. Their work was recently appraised and confirmed by a panel of experts in northeast China's Jilin Province.

  13. Progressive hemifacial atrophy

    Directory of Open Access Journals (Sweden)

    Abhijeet Sande

    2013-01-01

    Full Text Available Progressive hemifacial atrophy, also known as Parry-Romberg Syndrome, is an uncommon degenerative and poorly understood condition. It is characterized by a slow and progressive but self-limited atrophy affecting one side of the face. The incidence and the cause of this alteration are unknown. A cerebral disturbance of fat metabolism has been proposed as a primary cause. Possible factors that are involved in the pathogenesis include trauma, viral infections, heredity, endocrine disturbances and auto-immunity. The most common complications that appear in association to this disorder are: trigeminal neuralgia, facial paresthesia, severe headache and epilepsy. Characteristically, the atrophy progresses slowly for several years and, it becomes stable. The objective of this work is, through the presentation of a clinical case, to accomplish a literature review concerning general characteristics, etiology, physiopathology and treatment of progressive hemifacial atrophy.

  14. Reporting Continuous Progress

    Science.gov (United States)

    DeMott, Richard M.; Fistler, Ronald

    1973-01-01

    Described is the approach to evaluating student progress in the Iowa Braille and Sight Saving School which is based upon observable behaviors in all subject areas from kindergarten through grade 12. (MC)

  15. Core Hunter II: fast core subset selection based on multiple genetic diversity measures using Mixed Replica search

    Directory of Open Access Journals (Sweden)

    Beukelaer Herman De

    2012-11-01

    Full Text Available Abstract Background Sampling core subsets from genetic resources while maintaining as much as possible the genetic diversity of the original collection is an important but computationally complex task for gene bank managers. The Core Hunter computer program was developed as a tool to generate such subsets based on multiple genetic measures, including both distance measures and allelic diversity indices. At first we investigate the effect of minimum (instead of the default mean distance measures on the performance of Core Hunter. Secondly, we try to gain more insight into the performance of the original Core Hunter search algorithm through comparison with several other heuristics working with several realistic datasets of varying size and allelic composition. Finally, we propose a new algorithm (Mixed Replica search for Core Hunter II with the aim of improving the diversity of the constructed core sets and their corresponding generation times. Results Our results show that the introduction of minimum distance measures leads to core sets in which all accessions are sufficiently distant from each other, which was not always obtained when optimizing mean distance alone. Comparison of the original Core Hunter algorithm, Replica Exchange Monte Carlo (REMC, with simpler heuristics shows that the simpler algorithms often give very good results but with lower runtimes than REMC. However, the performance of the simpler algorithms is slightly worse than REMC under lower sampling intensities and some heuristics clearly struggle with minimum distance measures. In comparison the new advanced Mixed Replica search algorithm (MixRep, which uses heterogeneous replicas, was able to sample core sets with equal or higher diversity scores than REMC and the simpler heuristics, often using less computation time than REMC. Conclusion The REMC search algorithm used in the original Core Hunter computer program performs well, sometimes leading to slightly better results

  16. Progressive geometric algorithms

    Directory of Open Access Journals (Sweden)

    Sander P.A. Alewijnse

    2015-01-01

    Full Text Available Progressive algorithms are algorithms that, on the way to computing a complete solution to the problem at hand, output intermediate solutions that approximate the complete solution increasingly well. We present a framework for analyzing such algorithms, and develop efficient progressive algorithms for two geometric problems: computing the convex hull of a planar point set, and finding popular places in a set of trajectories.

  17. Earth's core and the geodynamo

    Science.gov (United States)

    Buffett

    2000-06-16

    Earth's magnetic field is generated by fluid motion in the liquid iron core. Details of how this occurs are now emerging from numerical simulations that achieve a self-sustaining magnetic field. Early results predict a dominant dipole field outside the core, and some models even reproduce magnetic reversals. The simulations also show how different patterns of flow can produce similar external fields. Efforts to distinguish between the various possibilities appeal to observations of the time-dependent behavior of the field. Important constraints will come from geological records of the magnetic field in the past.

  18. Magnetic Probing of Core Geodynamics

    Science.gov (United States)

    Voorhies, Coerte V.

    2004-01-01

    To better understand geomagnetic theory and observation, we can use spatial magnetic spectra for the main field and secular variation to test core dynmcal hypotheses against seismology. The hypotheses lead to theoretical spectra which are fitted to observational spectra. Each fit yields an estimate of the radius of Earth's core and uncertainty. If this agrees with the seismologic value, then the hypothes pass the test. A new way to obtain theoretical spectra extends the hydromagnetic scale analysis of Benton to scale-variant field and flow. For narrow scale flow and a dynamically weak field by the top of Earth's core, this yields a generalized Stevenson-McLeod spectrum for the core-source field, and a secular variation spectrum modulated by a cubic polynomial in spherical harmonic degree n. The former passes the tests. The latter passes many tests, but does not describe rapid dipole decline and quadrupole rebound; some tests suggest it is a bit hard, or rich in narrow scale change. In a core geodynamo, motion of the fluid conductor does work against the Lorentz force. This converts kinetic into magnetic energy which, in turn, is lost to heat via Ohmic dissipation. In the analysis at lentgh-scale l/k, if one presumes kinetic energy is converted in either eddy- overturning or magnetic free-decay time-scales, then Kolmogorov or other spectra in conflict with observational spectra can result. Instead, the rate work is done roughly balances the dissipation rate, which is consistent with small scale flow. The conversion time-scale depends on dynamical constraints. These are summarized by the magneto-geostrophic vertical vorticity balance by the top of the core, which includes anisotropic effects of rotation, the magnetic field, and the core- mantle boundary. The resulting theoretical spectra for the core-source field and its SV are far more compatible with observation. The conversion time-scale of order l20 years is pseudo-scale-invarient. Magnetic spectra of other

  19. Core competencies in internal medicine.

    Science.gov (United States)

    Porcel, José Manuel; Casademont, Jordi; Conthe, Pedro; Pinilla, Blanca; Pujol, Ramón; García-Alegría, Javier

    2012-06-01

    The working group on Competencies of Internal Medicine from the Spanish Society of Internal Medicine (SEMI) proposes a series of core competencies that we consider should be common to all European internal medicine specialists. The competencies include aspects related to patient care, clinical knowledge, technical skills, communication skills, professionalism, cost-awareness in medical care and academic activities. The proposal could be used as a working document for the Internal Medicine core curriculum in the context of the educational framework of medical specialties in Europe.

  20. Core Task and Organizational Reality

    DEFF Research Database (Denmark)

    Vikkelsø, Signe

    2015-01-01

    of core objects such as ‘task’ and ‘coordination,’ contemporary organization studies emphasize, much like other social science disciplines, broader topics such as ‘network,’ ‘identity,’ and ‘change.’ The paper argues that this altered focus and vocabulary is accompanied by a diminished ability to specify...... and intervene into the practical reality of organizations. It further argues that a discipline's core objects are not anachronisms to be discarded with, but crucial for specifying reality in ways that have proven practically relevant and still are....

  1. Prognostic Value of AIMS65 Score in Cirrhotic Patients with Upper Gastrointestinal Bleeding

    Directory of Open Access Journals (Sweden)

    Vinaya Gaduputi

    2014-01-01

    Full Text Available Introduction. Unlike Rockall scoring system, AIMS65 is based only on clinical and laboratory features. In this study we investigated the correlation between the AIMS65 score and Endoscopic Rockall score, in cirrhotic and noncirrhotic patients. Methods. This is a retrospective study of patients admitted with overt UGIB and undergoing esophagogastroduodenoscopy (EGD. AIMS65 and Rockall scores were calculated at the time of admission. We investigated the correlation between both scores along with stigmata of bleed seen on endoscopy. Results. A total of 1255 patients were studied. 152 patients were cirrhotic while 1103 patients were noncirrhotic. There was significant correlation between AIMS65 and Total Rockall scores in patients of both groups. There was significant correlation between AIMS65 score and Endoscopic Rockall score in noncirrhotics but not cirrhotics. AIMS65 scores in both cirrhotic and noncirrhotic groups were significantly higher in patients who died from UGIB than in patients who did not. Conclusion. We observed statistically significant correlation between AIMS65 score and length of hospitalization and mortality in noncirrhotic patients. We found that AIMS65 score paralleled the endoscopic grading of lesion causing UGIB in noncirrhotics. AIMS65 score correlated only with mortality but not the length of hospitalization or endoscopic stigmata of bleed in cirrhotics.

  2. An automated model-based aim point distribution system for solar towers

    Science.gov (United States)

    Schwarzbözl, Peter; Rong, Amadeus; Macke, Ansgar; Säck, Jan-Peter; Ulmer, Steffen

    2016-05-01

    Distribution of heliostat aim points is a major task during central receiver operation, as the flux distribution produced by the heliostats varies continuously with time. Known methods for aim point distribution are mostly based on simple aim point patterns and focus on control strategies to meet local temperature and flux limits of the receiver. Lowering the peak flux on the receiver to avoid hot spots and maximizing thermal output are obviously competing targets that call for a comprehensive optimization process. This paper presents a model-based method for online aim point optimization that includes the current heliostat field mirror quality derived through an automated deflectometric measurement process.

  3. National validation of the NACNS clinical nurse specialist core competencies.

    Science.gov (United States)

    Baldwin, Kathleen M; Clark, Angela P; Fulton, Janet; Mayo, Ann

    2009-01-01

    To validate the 75 core National Association of Clinical Nurse Specialists' (NACNS) clinical nurse specialist (CNS) competencies among practicing CNSs. Specific aims were to (a) determine the extent to which 75 core CNS competencies were used in current CNS practice, (b) determine the importance of those competencies to practicing CNSs, and (c) identify gaps between CNS core competencies and role expectations in current practice. A survey design was used with both paper-and-pencil and online instruments. The survey included 150 items and three open-ended questions. A convenience sampling method was used, which targeted practicing CNSs. Respondents (N=505) were practicing CNSs who entered the field as RNs between 1956 and 2006. The survey had a high degree of internal consistency reliability (0.967%) between the subscales. The 75 NACNS core competencies were found to be useful and important for CNSs. A few gaps were identified between CNS core competencies and CNS role expectations in current practice. No one method for validating competencies will be satisfactory for all situations; however, the processes and methods used in this study were well suited to accomplish the goal of validating CNS core competencies. The process described here may be instructive to leaders of other national and international professional organizations interested in developing and evaluating competencies. Core competencies are useful and important to currently practicing CNSs. The CNS role is growing internationally. Core CNS competencies can be a framework for CNS role development, education, and practice. As described here, a competency validation survey is one way to assure that CNSs are meeting healthcare needs.

  4. Producing gapped-ferrite transformer cores

    Science.gov (United States)

    Mclyman, W. T.

    1980-01-01

    Improved manufacturing techniques make reproducible gaps and minimize cracking. Molded, unfired transformer cores are cut with thin saw and then fired. Hardened semicircular core sections are bonded together, placed in aluminum core box, and fluidized-coated. After winding is run over box, core is potted. Economical method significantly reduces number of rejects.

  5. Multi-core Architectures and Streaming Applications

    NARCIS (Netherlands)

    Smit, Gerard J.M.; Kokkeler, André B.J.; Wolkotte, Pascal T.; Burgwal, van de Marcel D.; Mandoiu, I.; Kennings, A.

    2008-01-01

    In this paper we focus on algorithms and reconfigurable multi-core architectures for streaming digital signal processing (DSP) applications. The multi-core concept has a number of advantages: (1) depending on the requirements more or fewer cores can be switched on/off, (2) the multi-core structure f

  6. Core Stability Training for Injury Prevention

    OpenAIRE

    2013-01-01

    Context: Enhancing core stability through exercise is common to musculoskeletal injury prevention programs. Definitive evidence demonstrating an association between core instability and injury is lacking; however, multifaceted prevention programs including core stabilization exercises appear to be effective at reducing lower extremity injury rates. Evidence Acquisition: PubMed was searched for epidemiologic, biomechanic, and clinical studies of core stability for injury prevention (keywords: ...

  7. Predictors and progression of aortic stenosis in patients with preserved left ventricular ejection fraction

    DEFF Research Database (Denmark)

    Ersbøll, Mads; Schulte, Phillip J; Al Enezi, Fawaz

    2015-01-01

    We aimed to characterize the hemodynamic progression of aortic stenosis (AS) in a contemporary unselected cohort of patients with preserved left ventricular ejection fraction. Current guidelines recommend echocardiographic surveillance of hemodynamic progression. However, limited data exist on th...

  8. IDEOLOGY AND PROGRESS

    Directory of Open Access Journals (Sweden)

    Bogdan Constantin Mihăilescu

    2013-02-01

    Full Text Available The progress theme is very important for the ideologies of the Enlightenment political modernity. Moreover, it had received, with the help of the Enlightenment historicism and rationalism, a mythological dimension. Having in view the historical experience that we have today, it is necessary to give up on progress in thismillenarist meaning. But we are observing – as it also results from the political programs presented in the article – that some of the parties affiliated to the forementioned ideologies are approaching in an inconsistent manner the entire theme of the progress. The recession of this theme is part of a larger cultural context, specific for late modernity, when the ideologies seem to be exhausted. But ideologies survive and this fact certifies their power. They continue to impose different reference criteria on politics, and one of the most significant must remainthe progress. But there is also a more modest way to understand progress. Exactly this kind of approach is presented in this article, an approach which is best understood and commented by the help of Richard Rorty's works. Without having the progress as a desideratum, the negative use of power becomes easier. At the same time, the comparative evaluation of the economic, social or political initiatives,and also the social imperatives as solidarity, social cohesion, or the diminishing of the sufferings become more difficult to realize and pursue.

  9. [Progressive visual agnosia].

    Science.gov (United States)

    Sugimoto, Azusa; Futamura, Akinori; Kawamura, Mitsuru

    2011-10-01

    Progressive visual agnosia was discovered in the 20th century following the discovery of classical non-progressive visual agnosia. In contrast to the classical type, which is caused by cerebral vascular disease or traumatic injury, progressive visual agnosia is a symptom of neurological degeneration. The condition of progressive visual loss, including visual agnosia, and posterior cerebral atrophy was named posterior cortical atrophy (PCA) by Benson et al. (1988). Progressive visual agnosia is also observed in semantic dementia (SD) and other degenerative diseases, but there is a difference in the subtype of visual agnosia associated with these diseases. Lissauer (1890) classified visual agnosia into apperceptive and associative types, and it in most cases, PCA is associated with the apperceptive type. However, SD patients exhibit symptoms of associative visual agnosia before changing to those of semantic memory disorder. Insights into progressive visual agnosia have helped us understand the visual system and discover how we "perceive" the outer world neuronally, with regard to consciousness. Although PCA is a type of atypical dementia, its diagnosis is important to enable patients to live better lives with appropriate functional support.

  10. Coupling losses in perfluorinated multi-core polymer optical fibers.

    Science.gov (United States)

    Durana, Gaizka; Aldabaldetreku, Gotzon; Zubia, Joseba; Arrue, Jon; Tanaka, Chikafumi

    2008-05-26

    The aim of the present paper is to provide a comprehensive analysis of coupling losses in perfluorinated (PF) multi-core polymer optical fibers (MC-POFs), which consist of groups of 127 graded-index cores. In our analysis we take into account geometrical, longitudinal, transverse, and angular misalignments. We perform several experimental measurements and computer simulations in order to calculate the coupling losses for a PF MC-POF prototype. Based on these results, we propose several hints of practical interest to the manufacturer which would allow an appropriate connector design in order to handle conveniently the coupling losses incurred when connectorizing two PF MC-POFs.

  11. Visual Feedback for Rover-based Coring

    Science.gov (United States)

    Backes, Paul; Helmick, Daniel; Bajracharya, Max

    2008-01-01

    Technology for coring from a low-mass rover has been developed to enable core sample acquisition where a planetary rover experiences moderate slip during the coring operation. A new stereo vision technique, Absolute Motion Visual Odometry, is used to measure rover slip during coring and the slip is accommodated through corresponding arm pose updating. Coring rate is controlled by feedback of themeasured force of the coring tool against the environment. Test results in the JPL Marsyard show for the first time that coring from a low-mass rover with slip is feasible.

  12. Progress on the DPASS project

    Science.gov (United States)

    Galkin, Sergei A.; Bogatu, I. N.; Svidzinski, V. A.

    2015-11-01

    A novel project to develop Disruption Prediction And Simulation Suite (DPASS) of comprehensive computational tools to predict, model, and analyze disruption events in tokamaks has been recently started at FAR-TECH Inc. DPASS will eventually address the following aspects of the disruption problem: MHD, plasma edge dynamics, plasma-wall interaction, generation and losses of runaway electrons. DPASS uses the 3-D Disruption Simulation Code (DSC-3D) as a core tool and will have a modular structure. DSC is a one fluid non-linear, time-dependent 3D MHD code to simulate dynamics of tokamak plasma surrounded by pure vacuum B-field in the real geometry of a conducting tokamak vessel. DSC utilizes the adaptive meshless technique with adaptation to the moving plasma boundary, with accurate magnetic flux conservation and resolution of the plasma surface current. DSC has also an option to neglect the plasma inertia to eliminate fast magnetosonic scale. This option can be turned on/off as needed. During Phase I of the project, two modules will be developed: the computational module for modeling the massive gas injection and main plasma respond; and the module for nanoparticle plasma jet injection as an innovative disruption mitigation scheme. We will report on this development progress. Work is supported by the US DOE SBIR grant # DE-SC0013727.

  13. Failed culture change aimed at more service provision: A test of three agentic factors

    NARCIS (Netherlands)

    Jorritsma, P.Y.; Wilderom, Celeste P.M.

    2012-01-01

    Purpose – Headquarters managers of a medium-sized manufacturing company initiated a culture change in five of their dispersed wholesale units. The aim was for more external service quality. This paper aims to report the results of a test of three hypotheses, shedding light on the behavior of the

  14. Cultural adaptation and validation of a German version of the Arthritis Impact Measurement Scales (AIMS2).

    NARCIS (Netherlands)

    Rosemann, T.J.; Szecsenyi, J.

    2007-01-01

    OBJECTIVE: To validate a translated and culturally adapted version of the Arthritis Impact Measurement Scale (AIMS) 2 in primary care patients with osteoarthritis (OA) of the hip and knee. METHOD: The AIMS2 was translated into German and culturally adapted. The questionnaire then was administered to

  15. AIMS D2DB simulation for DUV and EUV mask inspection

    Science.gov (United States)

    Peng, Danping; Li, Ying; Satake, Masaki; Hu, Peter; Chen, Jerry; Hsu, S. C.; Lai, Rick; Lin, C. S.; Tuo, Laurent C. C.

    2012-02-01

    AIMS™ Die-to-Die (D2D) is widely used in checking the wafer printability of mask defects for DUV lithography. Two AIMS images, a reference and a defect image, are captured and compared with differences larger than certain tolerances identified as real defects. Since two AIMS images are needed, and since AIMS system time is precious, it is desirable to save image search and capture time by simulating reference images from the OPC mask pattern and AIMS optics. This approach is called Die-to-Database (D2DB). Another reason that D2DB is desirable is in single die mask, where the reference image from another die does not exist. This paper presents our approach to simulate AIMS optics and mask 3D effects. Unlike OPC model, whose major concern is predicting printed CD, AIMS D2DB model must produce simulated images that match measured images across the image field. This requires a careful modeling of all effects that impact the final image quality. We present a vector-diffraction theory that is based on solid theoretical foundations and a general formulation of mask model that are applicable to both rigorous Maxwell solver and empirical model that can capture the mask 3D-effects. We demonstrated the validity of our approach by comparing our simulated image with AIMS machine measured images. We also briefly discuss the necessary changes needed to model EUV optics. Simulation is particularly useful while the industry waits for an actinic EUV-AIMS tool.

  16. Parents' Views Regarding the Values Aimed to be Taught in Social Studies Lessons

    Science.gov (United States)

    Tay, Bayram; Yildirim, Kasim

    2009-01-01

    This study aimed at learning parents' ideas about the values aimed to be taught in Social Studies lessons in the 4th and 5th grades of the primary education and about values education. Study data were collected by administering "the Values Education I" and "Values Education II" questionnaire forms developed by the researchers.…

  17. Effects of anxiety on running with and without an aiming task

    NARCIS (Netherlands)

    Nibbeling, N.; Daanen, H.A.M.; Gerritsma, R.M.; Hofland, R.M.; Oudejans, R.R.D.

    2012-01-01

    State anxiety is known to affect far aiming tasks, but less is known about the effects of state anxiety on running and aiming while running. Therefore, in the current study participants ran on a treadmill at their preferred speed in a low- and highanxiety condition. In both conditions, running was c

  18. Internet Use with Learning Aim: Views of German Language Pre-Service Teachers

    Science.gov (United States)

    Yucel, Mukadder Seyhan

    2011-01-01

    The aim of this study is to indicate the views of teacher candidates of German Language Department at Education Faculty, Trakya University about the use of internet with the aim of learning. This study was designed as phenomenology which is one of the qualitative research methods. The study data were obtained via semi-constructed interview…

  19. Lessons from the AIME Approach to the Teaching Relationship: Valuing Biepistemic Practice

    Science.gov (United States)

    McMahon, Samantha; Harwood, Valerie; Bodkin-Andrews, Gawaian; O'Shea, Sarah; McKnight, Anthony; Chandler, Paul; Priestly, Amy

    2017-01-01

    The Australian Indigenous Mentoring Experience (AIME) is a national, extra-curricular mentoring programme that is closing the educational gap for young Indigenous Australians. So what is AIME doing that is working so well? This article draws on a large-scale classroom ethnography to describe the pedagogies that facilitate the teacher-student…

  20. Failed culture change aimed at more service provision: A test of three agentic factors

    NARCIS (Netherlands)

    Jorritsma, P.Y.; Wilderom, C.P.M.

    2012-01-01

    Purpose – Headquarters managers of a medium-sized manufacturing company initiated a culture change in five of their dispersed wholesale units. The aim was for more external service quality. This paper aims to report the results of a test of three hypotheses, shedding light on the behavior of the inv