WorldWideScience

Sample records for cor triatriatum sinistrum

  1. Cor triatriatum sinistrum: presentation of syncope and atrial tachycardia.

    Science.gov (United States)

    Avari, Malcolm; Nair, Sunil; Kozlowska, Zofia; Nashef, Samer

    2017-02-14

    We present a rather unusual cause for syncope associated with atrial tachycardia. A man aged 39 years presented with an episode of syncope and narrow complex tachycardia. Further investigations, including transoesophageal echocardiography, identified cor triatriatum sinistrum (CTS), a rare congenital abnormality characterised by the atrium being divided by a fibrous membrane. Although it is rare, there has been an increase in diagnosis due to developments in diagnostic imaging techniques. Symptoms are related to the size of fenestrations within the fibrous membrane. Presenting symptoms can mimic those seen in mitral stenosis. It is a condition that can occur in isolation, but it can also be associated with other cardiac abnormalities such as an atrial septal defect (ASD) (as in this case). Surgery is the definitive treatment (this man had surgical repair of CTS and closure of ASD) and should be considered at any age if there are any associated symptoms or complications. 2017 BMJ Publishing Group Ltd.

  2. Cor triatriatum sinistrum presenting as cardioembolic stroke: an unusual cause of adolescent hemiparesis.

    Science.gov (United States)

    Minocha, Anil; Gera, Sanjeev; Chandra, Nishith; Singh, Atampreet; Saxena, Sanjay

    2014-04-01

    Cor triatriatum sinistrum is a rare congenital cardiac malformation, in which the left atrium (LA) is divided into two distinct chambers by a fibromuscular membrane. Classically, the proximal (upper or superior) chamber of the LA receives pulmonary venous connections, whereas the distal (lower or inferior) chamber contains LA appendage and true atrial septum containing fossa ovalis. The distal chamber is in continuity with the atrioventricular valve, while the two chambers communicate through a defect in the membrane. The hemodynamics of cor triatriatum sinistrum are similar to that of mitral stenosis due to obstructive property of membrane. The majority of reported cases of cor triatriatum occur in infants with symptoms of pulmonary venous obstruction, with adult cases being rare. Herein, we describe an unusual case of cor triatriatum in a 17-year-old boy who presented for the first time with embolic cerebral infarction with left hemiparesis. © 2013, Wiley Periodicals, Inc.

  3. Cor triatriatum and hypertrophic cardiomyopathy.

    Science.gov (United States)

    Pellaton, Cyril; O'Mahony, Costas; Ludman, Andrew J; Sekhri, Neha; Mohiddin, Saidi

    2016-12-01

    : Cor triatriatum is a rare congenital anomaly known to be associated with other inherited heart diseases. We present a nonrestrictive cor triatriatum sinistrum associated with hypertrophic cardiomyopathy to illustrate how different multimodality noninvasive imaging techniques complement each other and can help with the diagnosis. To the best of our knowledge, this coexistence has not been previously reported.

  4. Thrombosed cor triatriatum sinistrum mimicking left atrial mass and causing unilateral pulmonary edema.

    Science.gov (United States)

    Gonzalez Lengua, Carlos A; Kumar, Pirkash; Cham, Matthew; Sanz, Javier

    2016-01-01

    46 year old female with history of progressive shortness of breath for 3 years associated with recurrent right lung infiltrates and hemoptisis. A computed tomography of the chest showed a left atrial mass suggestive of atrial myxoma confirmed with transesophageal echocardiogram. Contrary with findings from a dedicated EKG gated cardiac computed tomography suggestive of cor triatriatum with associated thrombus and less likely a neoplasm; findings later on confirmed during surgery. Cardiac CT offers superior spatial resolution and multi-planar image reconstructions, allowing improved characterization of cardiac structures and cardiac masses compared to other traditional cardiovascular imaging modalities. Copyright © 2016 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

  5. Anesthesia and cor triatriatum.

    Science.gov (United States)

    Scavonetto, Federica; Yeoh, Tze Yeng; Welch, Tasha L; Weingarten, Toby N; Sprung, Juraj

    2014-01-01

    Cor triatriatum sinistrum (CTS) and cor triatriatum dextrum (CTD) are rare congenital anomalies characterized by the presence of a perforated septum which divides the respective atrium into a proximal and distal chamber. This report reviews the perioperative course of patients with uncorrected cor triatriatum (CT) undergoing procedures requiring anesthesia. In addition, we performed a literature search that examines the experience of others regarding the peri-operative course of patients with CT. A computerized search of a medical record database was conducted to identify patients with a clinical diagnosis of uncorrected CTD and CTS undergoing surgical procedures. Descriptive statistics were used. We identified 12 adult patients with asymptomatic CTS (n = 7) and CTD (n = 5) who underwent 23 anesthetics. There were no perioperative complications which could be attributed directly to the anatomy of CT. Our observation and review of the literature suggest that patients with asymptomatic CT typically tolerate anesthesia and surgical procedures well.

  6. Cor triatriatum sinistrium in a 10 year old Nigerian: A case report ...

    African Journals Online (AJOL)

    We present a rare and first case of Cor triatriatum sinistrum (CT) in a patient who presents with dyspnoea, easy fatigability, chest pain, murmurs and typical ECG and 2D-echo findings. The purpose of presenting this case report is to highlight the distinctive manifestation of Cor triatriatum sinistrum and to provide a concise ...

  7. Cor triatriatum and stroke.

    Science.gov (United States)

    Diestro, Jose Danilo Bengzon; Regaldo, Joseph Justin Hipolito; Gonzales, Eddieson Masangcay; Dorotan, Maria Kristina Casanova; Espiritu, Adrian Isidro; Pascual, Jose Leonard Rivera

    2017-08-08

    Cor triatriatum sinistrum (CTS) is a congenital anomaly where the left atrium is divided into two compartments by a fibromuscular membrane. This report aims to add to the literature on a rare cardiac condition that can cause neurological morbidity. We report a case of a 19-year-old female with an infarct in the right middle cerebral artery (MCA) territory initially maintained on aspirin. Eighteen months later, she had recurrence of weakness, for which repeat transthoracic echocardiography (TTE) and re-evaluation of the first TTE demonstrated a hyperechoic membrane spanning the width of the left atrium, clinching the diagnosis of CTS. Despite anticoagulation with apixaban, she was admitted for a third stroke where she succumbed to hospital-acquired pneumonia. Among cases of CTS associated with stroke, anticoagulation and surgery were the main modes of treatment. This case has the longest follow-up and the first to demonstrate failure of antiplatelet therapy and anticoagulation. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Wong's anomaly - a rare variant of cor triatriatum.

    Science.gov (United States)

    Jayaprakash, K; Madhavan, Suresh; Sudha Kumary, V; George, Raju; Cletus, Nigil; Baiju, S

    2015-01-01

    Cor triatriatum sinistrum is an extremely rare congenital heart disease. It is even more uncommon in adults, and clinically significant mitral valve lesion complicating cor triatriatum is distinctly rare. Wong et al reported for the first time the rare combination of cor triatriatum sinister associated with severe mitral regurgitation and abnormal tensor apparatus of the mitral valve. We report a similar case and used the term Wong's anomaly for the syndrome, having membranous type of cor triatriatum sinistrum, severe mitral regurgitation and hypoplasia of the papillary muscles and short chordae. Color Doppler Echocardiography showed peculiar 'helmet sign' of mitral regurgitation, wherein the mitral regurgitation color jet fills the distal atrial chamber and abruptly ends in a horizontal plane as it is halted by the intra-atrial membrane. Copyright © 2015 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

  9. Cor triatriatum sinister.

    Science.gov (United States)

    Kadner, Alexander; Meszaros, Katharina; Mueller, Christoph; Schoenhoff, Florian; Hutter, Damian; Carrel, Thierry

    2014-01-01

    The cor triatriatum sinister is an uncommon congenital cardiac anomaly and reports in the literature are limited. It is often associated with other cardiac malformations, such as atrial septal defect, transposition of the great arteries, tetralogy of Fallot or atrioventricular septal defect. We present here a 6-year old boy who was diagnosed with cor triatriatum sinister, initially showing symptoms similar to mitral valve stenosis and congestive heart failure, and who underwent subsequent surgical correction using a left atrial approach. The fibromuscular membrane, separating the pulmonary veins from the mitral valve, was completely resected and postoperative echocardiography showed unobstructed pulmonary venous flow. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-thoracic Surgery. All rights reserved.

  10. Cor Triatriatum: A Review.

    Science.gov (United States)

    Jha, Ajay Kumar; Makhija, Neeti

    2017-06-01

    Cor triatriatum is a rare congenital cardiac anomaly defined by an abnormal septation within the atrium (left or right) leading to inflow obstruction to the respective ventricles. It exists either in isolated classical form or may be associated with simple to complex congenital cardiac anomalies. Several anatomical variants exist even in the classical form, and therefore, it may require multimodal diagnostic modalities to characterize and differentiate for better percutaneous interventional or surgical planning. It commonly presents in infancy but may remain undetected till death. Symptomatology typically mimics mitral and tricuspid stenosis in sinister and dexter varieties, respectively. However, features of systemic embolization, heart failure, atrial fibrillation, cyanosis, cardiac asthma, syncope, and sudden cardiac arrest have also been reported in the literature. Surgical correction under cardiopulmonary bypass is the preferred treatment. Nevertheless, balloon dilatation may be considered in anatomically compatible variants and in special circumstances, such as heart failure, pregnancy, or as a bridge to definitive treatment.

  11. Outcome after repair of cor triatriatum.

    Science.gov (United States)

    Yaroglu Kazanci, Selcen; Emani, Sitaram; McElhinney, Doff B

    2012-02-01

    Cor triatriatum represents cor triatriatum are related to pulmonary venous obstruction and pressure loading of the right side of the heart. The aim of this study was to describe our institutional experience with repair of cor triatriatum. From June 1963 to June 2010, 65 patients underwent repair at a median age of 7.2 months (range 2 days to 47.6 years). Among these patients, 49 (75%) had associated congenital heart defects. Atrial septal defect (n = 29), ventricular septal defect (n = 15), partially or totally anomalous pulmonary venous return (n = 14), mitral valve abnormalities (n = 11), and supravalvar mitral ring (n = 5) were the most common associated defects. Surgical treatment consisted of excision of the membrane, along with additional procedures in 47 patients (72%). Five patients had new postoperative supraventricular arrhythmias. During a median follow-up period of 5.4 years, no patients underwent reintervention for recurrent left atrial obstruction, 7 patients were noted to have minor residual cor triatriatum without obstruction, and 8 patients (including 4 diagnosed before cor triatriatum repair) had pulmonary vein stenosis, 6 of whom underwent intervention for that reason. In conclusion, in this large surgical series of patients who underwent repair of cor triatriatum, there were no cases of significant residual or recurrent cor triatriatum. Although the association between cor triatriatum and pulmonary vein stenosis has been described previously, the relative frequency of this condition in our cohort (>10%, including patients diagnosed before and after cor triatriatum repair) is noteworthy. Abnormalities of the mitral valve and a supravalvar mitral ring were also seen more often than the existing research would suggest, which may be another important consideration in evaluating and following these patients. Copyright © 2012. Published by Elsevier Inc.

  12. Cor triatriatum sinister: a case series.

    Science.gov (United States)

    Işık, Onur; Akyüz, Muhammet; Ayık, Mehmet Fatih; Levent, Ertürk; Atay, Yüksel

    2016-01-01

    As a highly rare congenital defect, cor triatriatum sinister represents only 0.1% of congenital cardiac anomalies. Depending on the degree of obstruction and the accompanying symptoms, cor triatriatum can be diagnosed at any age. This case series described 5 patients with cor triatriatum sinister who underwent operation. Five patients with cor triatriatum sinister were seen at our institution between 2007 and 2013. The demographic characteristics and surgical results of these patients are outlined in this retrospective review. The surgical approach consists of left or right atriotomy, excision of the obstructing membrane, and repair of the associated intracardiac anomalies. After an uneventful postoperative hospital stay, all patients were discharged 5-10 days postoperatively. There were no instances of recurrent constriction after surgical treatment of the cor triatriatum membrane. Patients were followed up for a median of 4 years and were symptom free. In the surgical management of this easily and fully treatable congenital cardiac anomaly, it is difficult to determine which atriotomy approach is comparatively more advantageous. However, in the management of cor triatriatum sinister, priority should be given to confirmation of the diagnosis and full resection of the membrane. Thus, the surgeon should not hesitate to perform additional incisions if deemed necessary.

  13. Benign mediastinal lymphadenopathy presenting as cor triatriatum.

    Science.gov (United States)

    Noel, Cory V; Pollard, Jessica; Permut, Lester; Ferguson, Mark; Hattendorf, Brandy

    2013-01-01

    This report describes a patient with a superior mediastinal mass and extensive intrathoracic lymphadenopathy referred for oncologic care. During her evaluation, an abnormal cardiovascular examination resulted in an echocardiographic evaluation and an unanticipated diagnosis of a highly obstructive left atrial cor triatriatum was uncovered. The patient underwent repair of cor triatriatum and lymph node biopsy shortly after the diagnosis was made. The biopsies revealed reactive lymph nodes with lymphatic dilation and no inflammatory or neoplastic features. To our knowledge, this case represents the first pediatric example of extensive mediastinal lymphadenopathy mimicking the appearance of a malignant process as a result of severe pulmonary venous hypertension. © 2012 Wiley Periodicals, Inc.

  14. Three's a Crowd - An Extremely Rare Case of Cor Triatriatum Dexter.

    Science.gov (United States)

    Elagizi, A; Marvin, R; O'Bryan, G; Vyas, V; Arcement, L

    2017-01-01

    Cor triatriatum is a congenital cardiac anomaly in which the left (sinister) or right (dexter) atrium is divided into two compartments by residual embryonic tissue, resulting in a tri-atrial heart. As cor triatriatum dextrum can present clinically in various ways and have multiple associated cardiac anomalies, this report attempts to contribute to what is known about this exceedingly rare disorder. A 40 year old Hispanic man with a medical history of gastritis presented with complaints of palpitations, dizziness and bilateral lower extremity edema. He was found to have atrial fibrillation and new onset heart failure. The patient was admitted for rate control and further evaluation, which revealed several cardiac anomalies. Initial 2D echocardiography demonstrated severe right atrial enlargement, right ventricular hypertrophy and an engorged coronary sinus, which prompted further assessment of the patient's cardiovascular anatomy. Transesophageal echocardiography (TEE) revealed a severely enlarged, septated right atrium with a possible unroofed coronary sinus and a small patent foramen ovale (PFO). Left- and right-heart catheterization established a coronary-cameral fistula between the right coronary artery (RCA) and right atrium, as well as left-to-right shunt. The patient improved clinically with conservative management including diet modification, furosemide and digoxin for fluid and rate control, and was referred to cardiothoracic surgery for further evaluation. Cor triatriatum dextrum is an extremely rare cardiac condition: In high-volume echocardiographic laboratories, prevalence is less than 0.01 percent. This case highlights the association between cor triatriatum and other congenital cardiac anomalies, including persistent left superior vena cava with an unroofed coronary sinus, PFO and left-to-right shunt; all of which were found in this patient. While cases of cor-triatriatum sinistrum often require correction in infancy (due to left sided heart failure

  15. Cor Triatriatum Sinister in a French Bulldog

    Directory of Open Access Journals (Sweden)

    Gustavo L. G. Almeida

    2012-01-01

    Full Text Available A 3-year-old male French Bulldog was evaluated due to recent history of intolerance to exercise and coughing. The clinical, radiographic, and echocardiographic findings were consistent with cor triatriatum sinister (CTS, a congenital heart anomaly in which the left atrium is subdivided into two compartments by an abnormal fibromuscular membrane. This defect has been rarely recognized in humans and in domestic cats. To the best of our knowledge, this is the first report of the disorder in the canine species.

  16. Transcatheter intervention in cor triatriatum sinister.

    Science.gov (United States)

    Patel, Mehul B; Samuel, Bennett P; Berjaoui, Wael K; Girgis, Reda E; Vettukattil, Joseph J

    2015-06-01

    Cor triatriatum sinister is a rare condition caused by a membrane in the left atrium, resulting in left ventricular inflow obstruction. This developmental anomaly is usually diagnosed in childhood. However, a rare presentation during adulthood is observed when the membrane is incomplete. Surgical excision of the membrane is the first line of treatment. We present a 51-year-old woman who underwent successful transcatheter balloon dilation with complete loss of the membrane waist and hemodynamic and symptomatic improvement. Copyright © 2015 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  17. Cor triatriatum dexter: A rare cause of childhood cyanosis

    Directory of Open Access Journals (Sweden)

    Ahmad Rustam bin Mohd Zainudin

    2012-01-01

    Full Text Available Cor triatriatum dexter is a rare congenital heart anomaly where the right atrium is divided into two chambers by a membrane. We report a boy who had persistent mild cyanosis and diagnosed to have cor triatriatum dexter with secundum atrial septal defect by transoesophageal echocardiography. Interestingly, he had persistent mild cyanosis despite insignificant obstruction to the right ventricular inflow and normal pulmonary artery pressure. The pathophysiology, approach to the diagnosis, and mode of treatment are also discussed.

  18. [Cor Triatriatum Diagnosed in Adulthood;Report of a Case].

    Science.gov (United States)

    Ijuin, Shinichi; Tobe, Satoshi; Sugiyama, Hironobu; Nosho, Hiroki; Hayashi, Taro; Yamaguchi, Masahiro; Tanimura, Nobuhiro; Oka, Takanori; Misato, Takuya; Tsunemi, Kotaro

    2015-07-01

    A 64-years-old man had cor triatriatum (Lucas-Schmidt type I A) with severe mitral regurgitation and atrial fibrillation. We perfomed resection of the anomalous septum between the accessory chamber and left atrium, and conducted mitral annuloplasty and maze procedure. Arrhythmia were not encountered after surgery. The maze procedure and resection of the anomalous septum with mitral surgery proved to be effective for atrial fibrillation with cor triatriatum.

  19. Truncus arteriosus communis in combination with cor triatriatum sinsitrum.

    Science.gov (United States)

    Klusmeier, Elmar; Haas, Nikolaus A; Sandica, Eugen

    2016-01-01

    Truncus arteriosus communis is a rare CHD, accounting for only 1% of all congenital cardiac abnormalities. It has been associated with other malformations of the heart, mainly truncal valve (bicuspid/quadricuspid) and aortic arch abnormalities such as right, interrupted, and hypoplastic aortic arch. Cor tratriatrum sinistrum is another rare CHD, and it has been associated with other cardiac defects such as anomalous pulmonary venous drainage, ventricular septal defect, coarctation of the aorta, and tetralogy of Fallot. The combination of truncus arteriosus communis and cor tratriatrum sinistrum has not been reported so far. This case study describes the diagnosis of a unique case, including these two very rare cardiac defects and the successful surgical treatment thereafter.

  20. Cor triatriatum sinister: a rare underlying cause of pulmonary hemosiderosis.

    Science.gov (United States)

    Peng, Shuhan; Xiao, Yunbin; Luo, Jinwen; Chen, Renwei; Huang, Peng; Liu, Pingbo; Deng, Xicheng

    2016-01-01

    Pulmonary hemosiderosis is a disorder with unknown cause and characterized by hemosiderin appreciation in alveolar interstitium from decomposed hemoglobin following alveolar capillary bleeding, which finally leads to pulmonary fibrosis. It can be divided into primary and secondary types in terms of its etiology. While primary types are related to autoimmunity, secondary types can be associated with cardiovascular and pulmonary causes such as mitral stenosis leading to pulmonary congestion. We report a case of cor triatriatum sinister in a child who presented with hemoptysis as a main clinical manifestation and had been previously diagnosed with idiopathic pulmonary hemosiderosis. Based on clinical signs and imaging examinations, we considered the hemoptysis was most likely due to cor triatriatum. The child underwent corrective surgery with uneventful recovery. The hemoptysis has not recurred any more after operation. Cardiovascular disease including cor triatriatum should be considered with regards to the etiology of pulmonary hemosiderosis.

  1. Left atrial calcification in a hemodialysis patient with cor triatriatum.

    Science.gov (United States)

    Peces, R; Pobes, A; Rodriguez, M; Simarro, C; Iglesias, G; Simarro, E

    2000-05-01

    Myocardial calcification is a rare manifestation of abnormal calcium metabolism seen in some patients with chronic renal failure. This report describes the transesophageal echocardiographic and spiral computed tomography (CT) findings in a young hemodialysis female with severe secondary hyperparathyroidism. These findings included calcification of the multiperforated membrane of a cor triatriatum and the wall of the left atrium.

  2. [Subtotal cor triatriatum sinister associated with bilateral partial anomalous pulmonary venous return].

    Science.gov (United States)

    Işık, Onur; Akyüz, Muhammet; Ayık, Mehmet Fatih; Atay, Yüksel

    2016-03-01

    Cor triatriatum sinister is a rare congenital cardiac pathology, representing only 0.1% of congenital cardiac anomalies, and often associated with other cardiac defects. In classic cor triatriatum sinister, the pulmonary venous chamber receives all pulmonary veins and drains into the left atrium through a variable-sized orifice. The case of a 4-month-old male patient who had subtotal cor triatriatum sinister associated with right and left upper anomalous pulmonary venous return is presented.

  3. Surgical repair of cor triatriatum sinister: the Mayo Clinic 50-year experience.

    Science.gov (United States)

    Saxena, Pankaj; Burkhart, Harold M; Schaff, Hartzell V; Daly, Richard; Joyce, Lyle D; Dearani, Joseph A

    2014-05-01

    Cor triatriatum is a rare congenital cardiac defect in which the atrium is divided into 2 chambers by a membrane causing obstruction to the blood flow in either the left atrium (cor triatriatum sinister) or the right atrium (cor triatriatum dexter) eventually leading to cardiac failure. We sought to review our surgical experience with cor triatriatum sinister. Twenty-five patients underwent surgical correction of cor triatriatum between May 1960 and September 2012. There were 11 males and 14 females with a mean age of 27.4 years (age range, 1 day to 73 years). All patients underwent excision of cor triatriatum membrane using cardiopulmonary bypass. Twenty patients (80%) required concomitant cardiac surgical procedures. There was no early mortality. None of the patients had any residual atrial obstruction. Two infants who had concomitant repair of complex congenital anomalies died at 2 and 5 months postoperatively after discharge from hospital. Kaplan-Meier survival at 10 years was 83%. All patients were in New York Heart Association class I or II at a mean follow-up of 12.8 years (maximum 44 years). Surgical repair of cor triatriatum provides satisfactory early and long-term survival with low risk for additional intervention. Cor triatriatum with complex congenital anomalies may be associated with adverse outcome. Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  4. Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report

    Directory of Open Access Journals (Sweden)

    Prapa Efi

    2011-06-01

    Full Text Available Abstract Cor triatriatum is a rare congenital cardiac malformation and it usually refers to the left atrium. We report an unusual case of cor triatriatum in a 33 - year old woman presented with congestive heart failure caused by left ventricular systolic dysfunction.

  5. Cor triatriatum presenting as heart failure with reduced ejection fraction: a case report.

    Science.gov (United States)

    Kokotsakis, John; Anagnostakou, Vania; Almpanis, George; Paralikas, Ioannis; Nenekidis, Ioannis; Kratimenos, Theodoros; Prapa, Efi; Tragotsalou, Nikolitsa; Lioulias, Achilleas; Mazarakis, Andreas

    2011-06-14

    Cor triatriatum is a rare congenital cardiac malformation and it usually refers to the left atrium. We report an unusual case of cor triatriatum in a 33 - year old woman presented with congestive heart failure caused by left ventricular systolic dysfunction.

  6. Siblings with Idiopathic Left Atrial Appendage Ostial Stenosis and Cor Triatriatum.

    Science.gov (United States)

    Okada, Seigo; Ishiguchi, Yukiko; Moritoh, Yuji; Shohi, Mayuko; Nakagawa, Naomi; Okamoto, Kengo; Kamada, Masahiro

    2016-07-01

    Isolated left atrial appendage (LAA) ostial stenosis is a very rare entity found coincidentally in adults by transesophageal echocardiography. A 3-month-old healthy infant was suspected as having cor triatriatum. His brother had a history of surgical treatment of cor triatriatum. A cardiac catheterization revealed a narrowed ostium of the LAA and confirmed the echocardiographic diagnosis of isolated LAA ostial stenosis. This is the first pediatric case of idiopathic LAA ostial stenosis. The siblings called our attention to the differential diagnosis and the etiopathogenesis between LAA ostial stenosis and cor triatriatum. © 2016, Wiley Periodicals, Inc.

  7. Cor triatriatum sinister with severe obstruction: a rare presentation in an adult.

    Science.gov (United States)

    Narayanapillai, Jayaprasad

    2016-08-05

    Cor triatriatum sinister is a rare congenital anomaly usually presenting in infancy or childhood. Most cases reported in adulthood have minimal obstruction. A case of critically obstructed cor triatriatum sinister presenting for the first time in adulthood is described here. The characteristic ECG, radiological and echocardiographic findings of this rare anomaly are demonstrated in this case report. The clinical features closely mimic mitral stenosis. The clues to differentiate cor triatriatum from other causes of left ventricular inflow obstruction are described. 2016 BMJ Publishing Group Ltd.

  8. Cor Triatriatum: Preoperative Diagnosis and Successful Surgical Correction in a Four-Year-Old Girl

    Directory of Open Access Journals (Sweden)

    Kiyomars Abbasi

    2010-09-01

    Full Text Available Cor triatriatum is defined as a membrane within the left atrium, which might lead to restricted pulmonary venous return. Diagnosis is usually achieved by echocardiography in early infancy. Therapy of choice is the excision of the membrane. Herein, successful correction of cor triatriatum in a 4-year-old girl is presented, and the clinical features, echocardiographic findings, and the surgical treatment are discussed.

  9. Cor triatriatum sinister with an intact interatrial septum and a decompressing vein in a toddler.

    Science.gov (United States)

    Binsalamah, Ziyad M; De León, Luis E; Heinle, Jeffrey S

    2017-08-01

    Cor triatriatum sinister is a very rare cardiac anomaly that may lead to pulmonary hypertension, right ventricular dilation, and eventually right heart failure. We report a case of a toddler who presented with respiratory distress and cardiomegaly and was found to have cor triatriatum sinister with a restrictive communication, decompressing vertical vein, pulmonary hypertension, severe tricuspid regurgitation, and severe right ventricular dysfunction. She underwent a successful surgical repair, with normalisation of right ventricular function and pulmonary artery pressure.

  10. Cor triatriatum dexter associated with atrial septal defect: Management in a complex clinical case.

    Science.gov (United States)

    Sozzi, Fabiola B; Montanaro, Claudia; Bacà, Laura; Viani, Giacomo M; Zilocchi, Massimo; Canetta, Ciro; Meazza, Roberto; Pavone, Laura; Lombardi, Federico

    2017-11-01

    The coexistence of an atrial septal defect and a prominent eustachian valve is a rare congenital anomaly, rarely reported in literature. Differentiation between a giant eustachian valve and cor triatriatum dexter can be difficult. A case of a large atrial septal defect associated with cor triatriatum dexter diagnosed by echocardiography in an asymptomatic woman is reported. A watchful waiting strategy was adopted. © 2017, Wiley Periodicals, Inc.

  11. Cor triatriatum dexter: A rare cause of cyanosis during neonatal period

    Directory of Open Access Journals (Sweden)

    Mohammed Hussien Alghamdi

    2016-01-01

    We report a 1-week-old child who presented with intermittent episodes of central cyanosis. Echocardiography, established, and bubble contrast study confirmed the diagnosis of an isolated cor-triatriatum dexter. The baby initially underwent an intervention by cardiac catheterization, which was unsuccessful in disrupting the membrane and re-direct the systemic venous flow to the right heart chambers. She subsequently had the cor-triatriatum dexter membrane resected via an uncomplicated open-heart surgery.

  12. [Silver-Russell syndrome (hemihypertrophy) and cor triatriatum in a newborn].

    Science.gov (United States)

    Ríos-Méndez, Raúl Enrique; Montero-Monar, Hernán Eduardo; Pernández-Alvarado, Antonio Pedro; Hidalgo-Flores, Einstein Gustavo

    2015-06-01

    Hemihypertrophy syndrome and cor triatriatum are extremely rare pathologies. Hemihypertrophy is defined as complete or partial overgrowth of one of the hemibodies. Cor triatriatum is a congenital heart disease characterized by a membrane which separates the left atrium into two chambers; if that membrane has a restrictive hole, it causes obstruction to blood passage from the pulmonary veins into the left ventricle causing hypertension and pulmonary edema. In this context, the patent ductus arteriosus can act as a means of decompression of the pulmonary circuit, because it allows the blood passage from the pulmonary artery to the aorta. We report a patient with Silver-Rusell syndrome (hemihypertrophy), cor triatriatum and ductus arteriosus with reverse flow. To our knowledge, this association of rare pathologies and this clinical presentation have not been described previously.

  13. Cor triatriatum dexter: A rare cause of cyanosis during neonatal period.

    Science.gov (United States)

    Alghamdi, Mohammed Hussien

    2016-01-01

    Cor-triatriatum dexter is an extremely rare congenital heart defect in which there is complete persistence of the right valve of embryonic sinus venosus that results in partitioning of the right atrium into a smooth and trabeculated portion. The smooth portion receives venous blood from inferior vena cava, superior vena cava, and coronary sinus while the trabeculated portion contains the right atrial appendage and the opening of tricuspid valve. We report a 1-week-old child who presented with intermittent episodes of central cyanosis. Echocardiography, established, and bubble contrast study confirmed the diagnosis of an isolated cor-triatriatum dexter. The baby initially underwent an intervention by cardiac catheterization, which was unsuccessful in disrupting the membrane and re-direct the systemic venous flow to the right heart chambers. She subsequently had the cor-triatriatum dexter membrane resected via an uncomplicated open-heart surgery.

  14. Cor triatriatum dexter and atrial septal defect in a 43-year-old woman.

    Science.gov (United States)

    Vukovic, Petar M; Kosevic, Dragana; Milicic, Miroslav; Jovovic, Ljiljana; Stojanovic, Ivan; Micovic, Slobodan

    2014-08-01

    Cor triatriatum dexter is a rare congenital heart anomaly in which a membrane divides the right atrium into 2 chambers. We report the case of a 43-year-old woman who had cor triatriatum dexter and a large atrial septal defect. During attempted percutaneous closure, the balloon disrupted the membrane and revealed that the defect had no inferior rim, precluding secure placement of an Amplatzer Septal Occluder. Surgical treatment subsequently proved to be successful. In patients with an incomplete membrane and a septal defect with well-defined rims, percutaneous treatment can be the first choice. In patients who have cor triatriatum dexter and unfavorable anatomic features or concomitant complex heart anomalies, open-heart surgery remains the gold standard for treatment.

  15. Cor triatriatum dexter, atrial septal defects, and pulmonary stenosis-a rare association.

    Science.gov (United States)

    Simsek, Ziya; Koza, Yavuzer; Tas, Hakan

    2014-04-01

    Cor triatriatum dexter (CTD) is an extremely rare congenital anomaly in which the right atrium is divided into 2 chambers by a membrane. The estimated incidence of cor triatriatum has been reported as 0.1% of congenital cardiac malformations. The septation of the right atrium in the setting of CTD is the result of failed resorption of the right valve of the sinus venosus. This results in anterolateral and posteromedial portions of the divided right atrium. CTD can be diagnosed at any age, especially if it is incidentally discovered. © 2014, Wiley Periodicals, Inc.

  16. A case series of patients with cor triatriatum dexter: unique cause of neonatal cyanosis.

    Science.gov (United States)

    Mackman, Chad A; Liedel, Jennifer L; Woods, Ronald K; Samyn, Margaret M

    2015-01-01

    Cor triatriatum dexter is a rare congenital heart defect that can lead to cyanosis in a newborn with an otherwise normal exam. The initial evaluation of these patients typically focuses on searching for a pulmonary etiology for arterial desaturation, which often leads to a negative work up. When cardiac evaluation is performed, it may be challenging because the heart lesion can be difficult to visualize on an echocardiogram. The diagnosis requires a high index of suspicion and thorough echocardiographic imaging. Once diagnosed, surgical repair can alleviate the shunt created by the defect. This case series describes all patients (3) with cor triatriatum dexter seen at Children's Hospital of Wisconsin from 2000 to 2013.

  17. Hybrid cutting balloon dilatation for treatment of cor triatriatum sinister in a cat.

    Science.gov (United States)

    Stern, Joshua A; Tou, Sandra P; Barker, Piers C A; Hill, Kevin D; Lodge, Andrew J; Mathews, Kyle G; Keene, Bruce W

    2013-09-01

    A hybrid surgical approach and balloon dilatation were performed successfully in a cat with cor triatriatum sinister and clinical signs of congestive heart failure. Left lateral thoracotomy was used to access the heart and cutting balloon followed by standard balloon dilatation were utilized to dilate the perforation in the anomalous left atrial membrane. Clinical signs resolved completely after dilation of the anomalous left atrial membrane. Based upon the outcome of this case, balloon dilatation appears to be a viable treatment option for cats affected with cor triatriatum sinister. Published by Elsevier B.V.

  18. Association of a unique form of cor triatriatum with tetralogy of Fallot.

    Science.gov (United States)

    Fuchigami, Tai; Koide, Masaaki; Kunii, Yoshifumi; Watanabe, Kazumasa

    2016-04-01

    Cor triatriatum is a rare cardiac anomaly sometimes associated with tetralogy of Fallot (TOF) and persistent left superior vena cava (PLSVC). We present the case of a 2-year-old girl who was diagnosed with a unique form of cor triatriatum that was associated with TOF and PLSVC. In this case, the abnormal membrane that arose from the posterior wall of the left atrium encircled the left superior vena cava (LSVC) in the left atrial cavity. Here, we discuss this rare case as well as the imaging studies and surgical strategy adopted.

  19. Catheter-Based Palliation in an Infant With Obstructed Cor Triatriatum.

    Science.gov (United States)

    Khoury, Michael; Sandoval, Juan Pablo; Grosse-Wortmann, Lars; Jaeggi, Edgar; Chaturvedi, Rajiv R

    2016-12-01

    A 33-day-old infant with obstructed cor triatriatum sinister and partial anomalous pulmonary venous drainage presented with respiratory distress and fever. Her suprasystemic pulmonary hypertension was relieved by opening the connection to the right atrium using balloon atrial septoplasty and septostomy, and to the inferior chamber using balloon dilation of a fenestration in the dividing membrane. This enabled extubation and discharge, with elective surgical repair at 2 months. To our knowledge, this is the youngest patient to receive a catheter intervention for obstructed cor triatriatum sinister, providing relief of pulmonary hypertension and postponement of surgical repair. Copyright © 2016 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  20. Imperforated cor triatriatum dexter in a dog with concurrent caudal vena cava wall mineralization

    NARCIS (Netherlands)

    Dobak, Tetyda Paulina; Starrak, Gregory; Linn, Kathleen; Snead, Elisabeth Christine Roberston

    2017-01-01

    BACKGROUND: Cor triatriatum dexter (CTD) is a rare congenital cardiac malformation with various manifestations and has been sporadically described in dogs. Clinically the dogs present with nonspecific signs of right heart failure or Budd-Chiari-like syndrome. Other associated concurrent

  1. [Diagnosis and evaluation of a patient with cor triatriatum using perioperative transesophageal echocardiography].

    Science.gov (United States)

    Kurazumi, Takuya; Suzuki, Takeshi; Morita, Yoshihisa; Masuda, Junich

    2014-03-01

    Cor triatriatum is a rare congenital cardiac anomaly accounting for only 0.1-0.4% of all congenital heart diseases usually diagnosed in infancy or childhood and rarely found in adults. It is characterized by fibromuscular membrane dividing the left atrium into two chambers. This congenital heart disease is reported to be frequently associated with variety of cardiac anomalies such as an atrial septal defect, anomalous pulmonary venous drainage, and persistent left superior vena cava. A woman with no cardiac history was admitted to the hospital due to acute heart failure and diagnosed as severe mitral regurgitation and cor triatriatum by pre-orerative transthoracic echocardiography. Emergency mitral valve plasty was undertaken because of the severity of mitral regurgitation without determining the detailed type of cor triatriatum. Thus, diagnosis of the type of cor triatriatum with perioperative transesophageal echocardiography (TEE) was required to establish correct cardiopulmonary bypass and determine the operative procedure. Perioperative TEE revealed that the type was Lucas-Schmidt- I A, and cardiopulmonary bypass was established safely. Operation was performed without any problems. The TEE skill of our anesthesiologists could contribute to the safe management of the cardiac surgery.

  2. Exercise-induced hypoxia secondary to an atrial septal defect and cor triatriatum dexter.

    Science.gov (United States)

    Eckersley, Luke G; Clements, Barry; Shipton, Stephen

    2016-04-01

    A 14-year-old boy presented to us with a diagnosis of severe asthma and oxygen desaturation of 76% on a 6-minute-walk test. A contrast echocardiogram revealed echocontrast in the left and right atria simultaneously. A secundum atrial septal defect and partial cor triatriatum dexter were diagnosed, and the atrial defect was closed by cardiac catheterisation.

  3. Cathether-based interventional strategies for cor triatriatum in the adult - feasibility study through a hybrid approach

    NARCIS (Netherlands)

    Li, Wilson W.; Koolbergen, David R.; Bouma, Berto J.; Hazekamp, Mark G.; de Mol, Bas A.; de Winter, Robbert J.

    2015-01-01

    Cor triatriatum is a rare congenital cardiac abnormality, consisting of an obstructing membrane between the pulmonary veins and the mitral valve in varying patterns. The entitiy can mimick the pathophysiology of mitral stenosis, necessitating surgical resection. Occasionally, percutaneous balloon

  4. Cathether-based interventional strategies for cor triatriatum in the adult - feasibility study through a hybrid approach.

    Science.gov (United States)

    Li, Wilson W; Koolbergen, David R; Bouma, Berto J; Hazekamp, Mark G; de Mol, Bas A; de Winter, Robbert J

    2015-07-14

    Cor triatriatum is a rare congenital cardiac abnormality, consisting of an obstructing membrane between the pulmonary veins and the mitral valve in varying patterns. The entitiy can mimick the pathophysiology of mitral stenosis, necessitating surgical resection. Occasionally, percutaneous balloon dilatation of the membrane has been successfully performed. We report two cases with cor triatriatum where intraoperative balloon dilatation of the membrane was attempted followed by surgical resection, to explore the feasibility of cathether-based interventional strategies for cor triatriatum. Various anatomical variations exist of cor triatriatum, depending on the drainage of the pulmonary veins and the drainage of the proximal chamber in the right or left atrium. Only isolated forms of cor triatriatum where all pulmonary veins ultimately drain into the left atrium can be recommended for percutaneous strategies. In addition, several anatomical characteristics should be considered to predict technical success of cathether-based interventional strategies, such as the location of the membrane, the degree of pulmonary vein stenosis, the extent of calcification, and the presence of other (congenital) cardiovascular abnormalities. Furthermore, long-term efficacy of these strategies remains to be confirmed. As such, surgical treatment of cor triatriatum remains the mainstay of treatment in adult patients, especially when other cardiovascular anomalies are present which require surgical correction.

  5. Transthoracic ultrasound guided balloon dilation of cor triatriatum dexter in 2 Rottweiler puppies.

    Science.gov (United States)

    Birettoni, F; Caivano, D; Bufalari, A; Giorgi, M E; Miglio, A; Paradies, P; Porciello, F

    2016-12-01

    Balloon dilation was performed in two Rottweiler puppies with cor triatriatum dexter and clinical signs of ascites using transthoracic echocardiographic guidance. The dogs were positioned on a standard echocardiography table in right lateral recumbency, and guide wires and balloon catheters were imaged by echocardiographic views optimized to allow visualization of the defect. The procedures were performed successfully without complications and clinical signs were resolved completely in both cases. Guide wires and balloon catheters appeared hyperechoic on transthoracic echocardiography image and could be clearly monitored and guided in real-time. These two cases demonstrate that it is possible to perform balloon catheter dilation of cor triatriatum dexter under transthoracic guidance alone. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Acquired Cor Triatriatum Sinister After the Fontan Operation and Successful Resection in a Child.

    Science.gov (United States)

    Zaidi, S Javed; Adhikari, Rishi R; El-Zein, Chawki; Siddiqui, Saad

    2017-11-01

    Cor triatriatum sinister is a rare congenital lesion encountered in children. It consists of a fibromuscular membrane that separates the left atrium into two chambers resulting in a triatrial heart and often occurs with other structural cardiac anomalies. The acquired form is uncommon and has only been reported after orthotopic heart transplantation or as a complication of infective endocarditis in adults. These cases were mostly because of hypertrophied atrial tissue or suture lines and torsion of the atrium. We describe the first case of acquired cor triatriatum late after the Fontan procedure with successful surgical resection in a child. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  7. Cor triatriatum sinister in a 43-year-old man with syncope.

    Science.gov (United States)

    Eichholz, Janet L; Hodroge, Samer S; Crook, Jerry J; Mack, John W; Wortham, Dale C

    2013-01-01

    Cor triatriatum sinister, a congenital cardiac anomaly involving a fibromuscular membrane that partitions the left atrium into 2 chambers, has been reported in only 0.1% to 0.4% of patients with congenital heart disease. The posterosuperior chamber receives blood from the pulmonary veins, and the anteroinferior chamber contains the left atrial appendage and mitral valve orifice. Most patients are diagnosed with the condition in infancy or childhood; adult cases are rare. We describe a case of cor triatriatum sinister in a 43-year-old man whose only presenting symptom was recurrent syncope. He underwent corrective resection of the membrane and was asymptomatic thereafter. In addition to discussing the patient's case, we review the relevant medical literature.

  8. Giant remnant of fetal circulation leading to cyanosis: pseudo-cor triatriatum dexter.

    Science.gov (United States)

    Yerebakan, Can; Valeske, Klaus; Esmaeili, Anoosh; Akintuerk, Hakan

    2014-05-01

    Remnants of the right valve of the sinus venosus, which fail to regress may present as an obstructing membrane within the right atrium as a very rare congenital anomaly. When associated with an atrial septal defect, primary cyanosis may occur due to a large right-to-left shunt. We report on a 1-week old girl with a pseudo-cor triatriatum dexter and immediate cyanosis after an uncomplicated birth. She was successfully treated with surgical excision of the obstructing membrane.

  9. Cor triatriatum em paciente adulta acompanhada durante a gestação Clinical follow-up of a pregnant woman with cor triatriatum

    Directory of Open Access Journals (Sweden)

    Rogério Tasca

    2007-03-01

    Full Text Available Cor triatriatum (CT é uma cardiopatia congênita rara que geralmente cursa com sintomas nos primeiros anos de vida. Na ausência de outras malformações cardíacas associadas e na dependência do grau de comunicação entre a câmara superior e o átrio esquerdo (AE, os pacientes podem atingir a idade adulta. Relatamos um caso de uma paciente adulta assintomática portadora de CT diagnosticado pelo ecocardiograma transtorácico (ETT e acompanhada clinicamente durante a gestação.Cor triatriatum (CT is a rare congenital cardiac anomaly that usually becomes symptomatic in the first years of life. If the condition is not associated with other cardiac defects, and depending on the degree of communication between the upper chamber and left atrium (LA, patients may reach adulthood. We report a case of an asymptomatic, adult, female patient with CT diagnosed by transthoracic echocardiogram (TTE and followed-up during pregnancy.

  10. Cor triatriatum sinister e hipertensão arterial pulmonar secundária em cão

    Directory of Open Access Journals (Sweden)

    T. Champion

    2014-02-01

    Full Text Available This paper describes the occurrence of cor triatriatum sinister, a rare cardiac malformation in dogs, associated with pulmonary edema and pulmonary hypertension in a 5-year-old Poodle female with history of acute dyspnea and cyanosis. The animal presented acute respiratory failure, heart failure with low cardiac output, progressing to acute tubular necrosis and death. The diagnosis was made posmortem due to the clinical instability of the dog. This malformation was diagnosed by the subdivision of the left atrium into two compartments separated by an abnormal fibromuscular membrane, absence of structural abnormalities of the mitral valve and thickening of pulmonary artery tunica media associated with renal tubular degeneration. The occurrence of cor triatriatum in dogs is most common in the right atrium, defined as cor triatriatum dexter. Additionally, pulmonary arterial hypertension associated with this malformation is described only in humans with this heart defect.

  11. Cor triatriatum: an unusual cause of elevated pulmonary capillary wedge pressure in a child with tetralogy of Fallot.

    Science.gov (United States)

    Gupta, Saurabh Kumar; Ramakrishnan, S; Doshi, Shrenik

    2013-10-01

    The coexistence of cor triatriatum and tetralogy of Fallot (TOF) is rare. Preoperative identification of cor triatriatum may be difficult owing to reduced pulmonary blood flow in patients with TOF. However, it is imperative to identify this rare combination as failure to identify obstruction to pulmonary venous egress may result in persistent pulmonary venous hypertension postoperatively. The authors discuss hemodynamic aspects of this rare coexistence in a 14-month-old child in whom pulmonary capillary wedge pressure was elevated despite right ventricular outflow obstruction. Copyright © 2012 Wiley Periodicals, Inc.

  12. Unusual case of new-onset heart failure due to cor triatriatum sinister.

    Science.gov (United States)

    Méndez, Ana Belén; Colchero, Teresa; Garcia-Picart, Joan; Vila, Montserrat; Subirana, Maria Teresa; Sionis, Alessandro

    2013-02-01

    We report the case of a 30-year old man who came to the emergency department of our hospital with acute left heart failure, and was diagnosed with a rare congenital anomaly (cor triatriatrum sinister), which can mimic a severe mitral stenosis. Cor triatriatum sinister is a rare anomaly (0.1% of all cases of congenital heart disease) that is seldom diagnosed in adult patients. The hallmark of this congenital defect is the presence of a fibromuscular membrane that divides the left atrium (LA) into two chambers: a postero-superior chamber into which the pulmonary veins drain and an infero-anterior chamber (true LA) containing the mitral valve and atrial appendage. Both chambers communicate through a membrane in which one or more drain holes can be found. When the hole is significantly obstructive, it results in increased venous and arterial pressures. Even though the definitive treatment of cor triatriatum is the surgical excision of the membrane, we present a balloon dilatation case with a good response to percutaneous therapy, both initially and in the ensuing months.

  13. Cor triatriatum or divided atriums: which approach provides the better understanding?

    Science.gov (United States)

    Bharucha, Tara; Spicer, Diane E; Mohun, Timothy J; Black, David; Henry, G William; Anderson, Robert H

    2015-02-01

    It is frequent, in the current era, to encounter congenital cardiac malformations described in terms of "cor triatriatum". But can hearts be truly found with three atrial chambers? The morphological method, emphasised by Van Praagh et al, states that structures within the heart should be defined on the basis of their most constant components. In the atrial chambers, it is the appendages that are the most constant components, and to the best of our knowledge, hearts can only possess two appendages, which can be of either right or left morphology. The hearts described on the basis of "cor triatriatum", nonetheless, can also be analysed on the basis of division of either the morphologically right or the morphologically left atriums. In this review, we provide a description of cardiac embryology, showing how each of the atrial chambers possesses part of the embryological body, along with an appendage, a vestibule, a venous component, and a septum that separates them. We then show how it is, indeed, the case that the hearts described in terms of "cor triatriatum" can be readily understood on the basis of division of these atrial components. In the right atrium, it is the venous valves that divide the chamber. In the left atrium, it is harder to provide an explanation for the shelf that produces atrial division. We also contrast the classic examples of the divided atrial chambers with the vestibular shelf that produces supravalvar stenosis in the morphologically left atrium, showing that this form of obstruction needs to be distinguished from the fibrous shelves producing intravalvar obstruction.

  14. Complete A-V block: incidental or a part of cor triatriatum dexter.

    Science.gov (United States)

    Guler, Y; Akgun, T; Toprak, C; Guler, A; Esen, A M

    2014-05-01

    Cor triatriatum dexter (CTD) is an extremely rare cardiac anomaly in which the right atrium is divided into two distinct chambers by a membrane. The persistence of the right valve of sinus venosus results in a complete septation of the right atrium. This anomaly is frequently associated with other right-sided cardiac abnormalities. Its clinical manifestation and the need for intervention are determined by the number and the size of the fenestrations on the membrane, associated cardiac anomalies and arrhythmias. We describe a case of CTD in a patient with complete atrioventricular (A-V) block.

  15. Cor triatriatum dexter, a very rare congenital anomaly presented in a complex pathological context – case presentation

    Directory of Open Access Journals (Sweden)

    Gozar Liliana

    2014-08-01

    Full Text Available Background Cor triatriatum dexter is an extremely rare congenital anomaly, and in most cases, without hemodynamic significance. Congenital cytomegalovirus infection is the most common viral infection, the majority of infected infants being asymptomatic and only 5-15% being symptomatic in the neonatal period.

  16. Fetal cor triatriatum dexter: a report of two cases associated with nuchal edema in early second trimester

    DEFF Research Database (Denmark)

    Maroun, L.L.; Graem, N.; Skibsted, L.

    2008-01-01

    Two early-2nd-trimester fetuses were aborted as a result of nuchal edema and suspected severe heart malformation. At autopsy one fetus demonstrated nuchal edema, mild hydronephrosis, and cor triatriatum dexter associated with ventricular septal defect and tubular hypoplasia of the aortic arch...

  17. Stent placement for palliation of cor triatriatum dexter in a dog with suspected patent foramen ovale.

    Science.gov (United States)

    Barncord, Kristin; Stauthammer, Christopher; Moen, Sean L; Hanson, Melissa; Gruenstein, Daniel H

    2016-03-01

    An 11 month old spayed, female dog presented with exercise intolerance and cyanosis upon exertion. Echocardiography revealed an imperforate cor triatriatum dexter with mild tricuspid valve dysplasia, an underfilled right ventricle and significant right to left shunting across a presumptive patent foramen ovale. Balloon dilation of the abnormal atrial membrane was initially successful in creating a communication between the right atrial chambers, but stenosis of the original perforation and persistent clinical signs prompted a second intervention. A balloon expandable biliary stent was placed across the abnormal partition, improving caudal venous return to the right ventricle and reducing the right to left shunt. Three months after stent placement, resting oxygen saturation had normalized. Six months after stent placement, exercise tolerance had improved and exertional cyanosis had resolved. Long term follow up will be necessary to assess for remodeling of the right ventricle with improved venous return. Stent placement can be considered as a palliative treatment option for cor triatriatum dexter, especially for stenosis post-balloon dilation. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Morphological dilemma: Anomalous pulmonary venous confluence or cor triatriatum-does it matter?

    Science.gov (United States)

    Muthialu, Nagarajan

    2018-01-01

    Cardiac variant of total anomalous pulmonary venous return is a rare entity, whereby all the pulmonary veins drain directly to the right atrium or coronary sinus. The effective left heart blood flow channels through a small stretched patent foramen ovale and can often be confused with a variant of cor triatriatum. Cor triatriatum is a rare congenital cardiac anomaly where pulmonary veins drain to a persistent chamber above the left atrium with a membrane separating these two. There persists either a small aperture directly from the true to the accessory left atrium or none at all. Where there is no such aperture, it is often physiologically akin to the cardiac variant of total anomalous pulmonary venous return described above. Such morphological differentiation is often challenging in a clinical situation, but the effective treatment remains the same. It involves removal of the common wall between the two chambers and baffling the pulmonary veins effectively to the left atrium. We describe such a case where the pulmonary venous return is to the right atrium, managed recently in our centre, and discuss the morphological differences between these two.

  19. Anaesthetic management for balloon dilation of cor triatriatum dexter in a dog.

    Science.gov (United States)

    De Monte, Valentina; Staffieri, Francesco; Caivano, Domenico; Bufalari, Antonello

    2015-06-10

    A three-month-old female Rottweiler puppy was referred for intravascular correction of a previously identified cor triatriatum dexter. Echocardiography confirmed the presence of a hyperechoic membrane that divided the right atrium into a cranial and caudal chamber. A foramen in this membrane allowed the blood to flow from the caudal to the cranial chamber. Balloon dilation of the defect under transthoracic echocardiographic guidance was scheduled for the following day. The dog was premedicated with 0.5 μg/kg sufentanil and 0.2 mg/kg midazolam administered intravenously. General anaesthesia was induced with 2 mg/kg propofol and maintained with inhaled isoflurane in oxygen; at the same time, a constant rate infusion of 0.5 μg/kg/h sufentanil was administered by means of an infusion pump. Uneventful ventricular and supraventricular tachyarrhythmias developed during the placement of catheters and balloon dilation. At the end of procedure, when the guide wire and balloon catheter were removed, normal sinus rhythm was observed. To the authors' knowledge, no previous reports have described the anaesthetic management of a balloon dilation procedure for cor triatriatum dexter in dogs.

  20. Wheezing as a sign of cor triatriatum sinister culminating in multiple organ failure.

    Science.gov (United States)

    Lee, Meng-Luen; Chen, Ying-Cheng; Lee, Ming-Sheng; Chien, Jien-Wen

    2014-12-01

    Cardiac asthma or cardiac wheezing (CW) refers to a syndrome of dyspnea and wheezing that mimicks asthma clinically. Reported herein is the case of a 2-month-old boy who presented with refractory wheezing as a sign of cor triatriatum sinister (CTS) that culminated in overwhelming multiple organ failure in a short time. On the day of admission, oxygen saturation (SpO2 ) was 20,000 pg/mL. Two-dimensional echocardiography with Doppler showed CTS, which was complicated with severe pulmonary arterial hypertension due to flagrant pulmonary venous obstruction. Cardiac surgery was undertaken, after which pulmonary edema subsided, SpO2 increased to ≥96%, and NTproBNP dropped to normal. He was discharged 11 days later, and was free of cardiac, pulmonary, renal, and neurological sequelae at 24 month follow up. © 2014 Japan Pediatric Society.

  1. Cor Triatriatum Sinister Identified after New Onset Atrial Fibrillation in an Elderly Man

    Directory of Open Access Journals (Sweden)

    Ignacio A. Zepeda

    2014-01-01

    Full Text Available A 73-year-old man with new onset atrial fibrillation with rapid ventricular response underwent transthoracic echocardiography that revealed an echogenic linear structure along the left atrium, suggestive of cor triatriatum sinister (CTS. CTS was confirmed with transesophageal echocardiography which demonstrated a proximal accessory atrium receiving pulmonary venous flow separated from a distal true atrium by a fibromuscular membrane with a large fenestration allowing flow between the chambers. In CTS, the left atrium is divided into proximal and distal chambers by a fenestrated fibromuscular septum. This cardiac anomaly accounts for 0.1% of cases of congenital heart disease and rarely presents in adults. CTS is primarily diagnosed with echocardiography and is associated with left atrial enlargement and development of atrial fibrillation. Treatment options depend on size of the communication between proximal and distal chambers, the gradient across the membrane, and the position of pulmonary veins. In some instances, surgical resection of the membrane that divides the left atrium is warranted.

  2. Cor triatriatum izquierdo diagnosticado tardíamente. Reporte de caso

    Directory of Open Access Journals (Sweden)

    Francisco J. Vázquez-Roque

    2016-09-01

    Full Text Available El Cor Triatriatum izquierdo es una anomalía congénita cardiaca rara. Es infrecuente que estos pacientes sobrepasen la edad de 40 años sin su corrección quirúrgica. El objetivo de este artículo fue el de presentar un paciente de 43 años que fue intervenido quirúrgicamente a la edad de 5 años para el cierre de una comunicación interauricular y donde el diagnóstico de esta entidad no se realizó. Un mes antes del ingreso comienza con palpitaciones y disnea a los moderados esfuerzos. Con la ecografía transesofágica se hace el diagnóstico de esta anomalía, la cual se asociaba a una insuficiencia mitral y fibrilación auricular. Se procedió a la resección de la membrana fibromuscular y la reparación de dos hendiduras congénitas en el borde del velo anterior de la válvula mitral con buenos resultados. Un año después el paciente se encuentra asintomático y en la ecocardiografía transtoráxica se muestra una aurícula izquierda unicameral con una regurgitación mitral trivial.

  3. Cor triatriatum dexter versus prominent Eustachian valve in an adult congenital heart disease patient.

    Science.gov (United States)

    Martínez-Quintana, Efrén; Rodríguez-González, Fayna; Marrero-Santiago, Hector; Santana-Montesdeoca, Jose; López-Gude, María Jesús

    2013-01-01

    An eustachian valve (EV) remnant, if present, is usually noted by the presence of a thin ridge or a crescent-shaped fold of endocardium arising from the anterior rim of the inferior vena cava orifice due to the persistence of the right sinus venosus valve. Though the embryologic explanation of cor triatriatum dexter (CTD) is the same as that of the normal formation of the EV--lack of regression of the right sinus venosus valve--it is usually called CTD or divided right atrium when there are attachments on the atrial septum giving the appearance of a divided atrium. However, it's called prominent eustachian valve when the right sinus venosus valve has partly regressed, with no remaining septal attachments and without the appearance of a divided atrium. We present the case of an adult patient with an atrial septal defect with a high insertion of a giant EV, which mimics the echocardiographic appearance of divided right atrium. © 2012 Wiley Periodicals, Inc.

  4. Imperforated cor triatriatum dexter in a dog with concurrent caudal vena cava wall mineralization.

    Science.gov (United States)

    Dobak, Tetyda Paulina; Starrak, Gregory; Linn, Kathleen; Snead, Elisabeth Christine Roberston

    2017-01-03

    Cor triatriatum dexter (CTD) is a rare congenital cardiac malformation with various manifestations and has been sporadically described in dogs. Clinically the dogs present with nonspecific signs of right heart failure or Budd-Chiari-like syndrome. Other associated concurrent cardiovascular anomalies are commonly reported. Diagnosis and full characterization of this complex malformation requires careful investigation and often a multimodal imaging approach. A 10-week-old, male intact, Golden Retriever was presented with clinical signs of stunted growth, anorexia, and progressive ascites. CTD imperforate with sole separation of the caudal vena cava (CdVC) and concurrent venous wall mineralization was conjointly diagnosed and fully characterized by echocardiography, non-selective angiography, computed tomography angiography and cardiac magnetic resonance imaging (MRI). This was successfully treated surgically and the dog returned to normal activity. To the author's knowledge, this is the first case of CTD imperforate separating the CdVC from the right atrium (RA) with presumed secondary CdCV wall and hepatic parenchyma mineralization reported in a dog. CTD is an important and potentially correctable cause for the development of ascites in a young puppy. Accurate diagnosis of this complex cardiac anomaly is important for selection of the most appropriate curative treatment option.

  5. Surgical Treatment of Cor Triatriatum Sinister in a Cat Under Cardiopulmonary Bypass.

    Science.gov (United States)

    Borenstein, Nicolas; Gouni, Vassiliki; Behr, Luc; Trehiou-Sechi, Emilie; Petit, Amandine; Misbach, Charlotte; Raillard, Mathieu; Retortillo, José Luis; Pouchelon, Jean-Louis; Pierrel, Alain; Laborde, François; Chetboul, Valérie

    2015-11-01

    To report the surgical repair of cor triatriatum sinister (CTS) incorporating heart-beating cardiopulmonary bypass (CPB) in a cat. Clinical case report. Fourteen-month-old, 5.9-kg male castrated Maine Coon cat. The cat had a 3 month history of inappetance, weight loss, and recurrent pulmonary edema. CTS with severe systolic pulmonary arterial (SPA) hypertension (124 mm Hg) was diagnosed by 2D echocardiography, color flow and continuous wave Doppler modes, and left atrial and pulmonary angiography. Surgery was performed through a left intercostal thoracotomy. CPB was initiated and the heart was kept beating. The left atrial appendage was opened and the intra-atrial membrane was excised. After 48 hours, the cat was doing well. Reduced SPA pressure (52 mm Hg) with decreased right heart enlargement was observed on ultrasound examination and the cat was discharged 6 days after surgery with oral antibiotics for 10 days, aspirin, and furosemide. Four months after surgery, the cat presented with increased activity and weight gain and was completely asymptomatic. Transthoracic echocardiography showed a marked improvement of all echo-Doppler variables with disappearance of SPA hypertension (24 mm Hg). Four years after surgery, the cat was still doing well with no recurrence of clinical signs despite the lack of medical treatment. CTS in the cat may be successfully treated by surgery facilitated by use of CPB leading to early and long-term substantial improvement in clinical status and cardiac function. CTS can safely be repaired under CPB in cats. © Copyright 2015 by The American College of Veterinary Surgeons.

  6. Anaesthetic management of a child with "cor-triatriatum" and multiple ventricular septal defects - A rare congenital anomaly

    Directory of Open Access Journals (Sweden)

    Sriram Sabade

    2010-01-01

    Full Text Available Cor-triatriatum is a rare congenital cardiac anomaly. It accounts for 0.1% of congenital heart diseases. Its association with multiple ventricular septal defects (VSD is even rarer. A five-month-old baby was admitted with respiratory distress and failure to thrive. Clinical examination revealed diastolic murmur over mitral area. Chest X-ray showed cardiomegaly. Haematological and biochemical investigations were within normal limits. Electrocardiogram showed left atrial enlargement. 2D echo showed double-chambered left atrium (cor-triatriatum, atrial septal defect (ASD and muscular VSD with moderate pulmonary arterial hypertension. The child was treated with 100% oxygen, diuretics and digoxin and was stabilized medically. We used balanced anaesthetic technique using oxygen, air, isoflurane, fentanyl, midazolam and vecuronium. Patient was operated under cardiopulmonary bypass (CPB with moderate hypothermia. Through right atriotomy abnormal membrane in the left atrium was excised to make one chamber. VSD were closed with Dacron patches and ASD was closed with autologous pericardial patch. Patient tolerated the whole procedure well and was ventilated electively for 12h in the intensive care unit. He was discharged on the 10 th postoperative day.

  7. Cor triatriatum dexter and coarctation of the aorta--a rare association in a 7-year-old child with type 1 neurofibromatosis.

    Science.gov (United States)

    Omeje, Ikenna; Christov, Georgi; Khambadkone, Sachin; Hsia, Tain-Yen

    2015-02-01

    Cor triatriatum dexter is an extremely rare congenital anomaly of the right atrium. It occurs because of the persistence of the right sinus venosus valve, resulting in partitioning of the right atrium. Most of the described cases of cor triatriatum dexter in the literature were incidental findings on echocardiogram or at necropsy. We present a case report of a 7-year-old girl who was referred to us for further assessment, with a possible diagnosis of coarctation of the aorta. Initial investigations confirmed not only the presence of a long segment coarctation of the aorta, but also a large obstructive membrane in the right atrium. A catheter intervention was performed to stent the coarctation segment, and the fibro-muscular shelf in the right atrium was surgically resected.

  8. Catheter ablation of persistent atrial fibrillation in a patient with cor triatriatum sinister demonstrating a total common trunk of the pulmonary vein.

    Science.gov (United States)

    Tokuda, Michifumi; Yamane, Teiichi; Tokutake, Kenichi; Yokoyama, Kenichi; Hioki, Mika; Narui, Ryohsuke; Tanigawa, Shin-Ichi; Yamashita, Seigo; Inada, Keiichi; Matsuo, Seiichiro; Yoshimura, Michihiro

    2016-02-01

    A 57-year-old male with persistent atrial fibrillation (AF) was referred for catheter ablation. Multidetector computed tomography (MDCT) revealed that a membrane divided the left atrium into two chambers, thus indicating the presence of cor triatriatum sinister. A 3D image reconstructed by MDCT showed that the accessory atrium received the left common and the right side PVs, as if it were a total common trunk, and this then flowed into the main atrium. After isolation of the pulmonary vein and posterior wall from the left atrium, AF could not be induced by any programmed pacing. The patient has remained free from AF during the 1 year of follow-up.

  9. Surgical correction of cor triatriatum sinister in the paediatric population: mid-term results in 15 cases.

    Science.gov (United States)

    Ozyuksel, Arda; Yildirim, Ozgur; Avsar, Mustafa; Hayirlioglu, Mehmet; Demiroluk, Sener; Kucukosmanoglu, Osman; Bilal, Mehmet Salih

    2015-01-01

    Cor triatriatum sinister (CTS) is a rare developmental cardiac abnormality resulting in left ventricular inflow obstruction. In this report, we aimed to present our mid-term results of early childhood patients operated for CTS and associated cardiac abnormalities. We enrolled 15 patients with CTS who were operated by a single surgeon between 2001 and 2013. A retrospective analysis was performed in order to determine the demographics, operative and postoperative results of the patients. The median age was 14 months and the median body weight was 8.2 kg at the time of operation. Fourteen patients had concomitant cardiac pathology. Three of the patients had atrial septal defect and 1 of the patients had partial abnormal pulmonary venous connection, whereas 4 of the patients had both. In 2 cases of complete atrioventricular septal defect, 1 case with ventricular septal defect, 1 case with patent ductus arteriosus, 1 case with double outlet right ventricle and another case with tetralogy of Fallot, complete repair was performed together with membrane resection in the left atrium (LA). The mean preoperative left atrial gradient was 13.3 mmHg, whereas the mean LA pressure at the first postoperative year was 4.2 mmHg. There was 1 case with early mortality due to septic multiorgan failure secondary to pneumonia. CTS is a rare congenital cardiac anomaly in which the results of the corrective surgery are encouraging. Early and long-term outcomes may be variable according to the associated congenital heart defects. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  10. Mutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and Mice.

    Science.gov (United States)

    Muggenthaler, Martina M A; Chowdhury, Biswajit; Hasan, S Naimul; Cross, Harold E; Mark, Brian; Harlalka, Gaurav V; Patton, Michael A; Ishida, Miho; Behr, Elijah R; Sharma, Sanjay; Zahka, Kenneth; Faqeih, Eissa; Blakley, Brian; Jackson, Mike; Lees, Melissa; Dolinsky, Vernon; Cross, Leroy; Stanier, Philip; Salter, Claire; Baple, Emma L; Alkuraya, Fowzan S; Crosby, Andrew H; Triggs-Raine, Barbara; Chioza, Barry A

    2017-01-01

    Orofacial clefting is amongst the most common of birth defects, with both genetic and environmental components. Although numerous studies have been undertaken to investigate the complexities of the genetic etiology of this heterogeneous condition, this factor remains incompletely understood. Here, we describe mutations in the HYAL2 gene as a cause of syndromic orofacial clefting. HYAL2, encoding hyaluronidase 2, degrades extracellular hyaluronan, a critical component of the developing heart and palatal shelf matrix. Transfection assays demonstrated that the gene mutations destabilize the molecule, dramatically reducing HYAL2 protein levels. Consistent with the clinical presentation in affected individuals, investigations of Hyal2-/- mice revealed craniofacial abnormalities, including submucosal cleft palate. In addition, cor triatriatum sinister and hearing loss, identified in a proportion of Hyal2-/- mice, were also found as incompletely penetrant features in affected humans. Taken together our findings identify a new genetic cause of orofacial clefting in humans and mice, and define the first molecular cause of human cor triatriatum sinister, illustrating the fundamental importance of HYAL2 and hyaluronan turnover for normal human and mouse development.

  11. NJP VOLUME 40 No 1B

    African Journals Online (AJOL)

    Prof Ezechukwu

    2012-05-15

    May 15, 2012 ... Abstract We present a rare and first case of Cor triatriatum sinis- trum (CT) in a patient who presents with dyspnoea, easy fatigability, chest pain, murmurs and typical. ECG and 2D-echo findings. The purpose of presenting this case report is to highlight the distinctive manifestation of Cor triatriatum sinistrum ...

  12. A Five (5) chamber heart (Cor Triatriatum) in Infancy: A rare ...

    African Journals Online (AJOL)

    Five-chambered heart is extremely rare in children. We report a case of asymptomatic five chamber heart detected in infancy. The patient is 2-day-old and managed in a special care baby unit (SCBU) for neonatal sepsis. During routine follow-up at the age of 1 month, she was found to have an asymptomatic murmur.

  13. Acute cor pulmonale.

    Science.gov (United States)

    Jardin, François; Vieillard-Baron, Antoine

    2009-02-01

    Acute cor pulmonale is a form of acute right heart failure produced by a sudden increase in resistance to blood flow in the pulmonary circulation, which is now rapidly recognized by bedside echocardiography. In the clinical setting, acute cor pulmonale is mainly observed as a complication of massive pulmonary embolism or acute respiratory distress syndrome. In acute respiratory distress syndrome, the worsening effect of mechanical ventilation has been recently emphasized. As a general rule, the treatment consists in rapidly reducing resistance to blood flow in the pulmonary circulation, obtained by a specific strategy according to etiology.

  14. [Chronic cor pulmonale].

    Science.gov (United States)

    Swidnicka-Szuszkowska, B

    2000-10-01

    Cor pulmonale is defined as "hypertophy of the right ventricle resulting from diseases affecting the function and/or structure of the lungs, except when these pulmonary alterations are the result of diseases that primarily affect the left side of the heart, as congenital heart disease". Pulmonary hypertension is a frequent hemodynamic complication associated with a wide variety of respiratory systems disorders whose only common physiologic abnormalities are alveolar hypoxia and consequent arterial hypoxemia of longterm duration. The sustained elevation in pulmonary arterial hypertension is thought to be mediated through two pathophysiologic vascular mechanism: 1) persistent vasoconstriction and 2) vascular structural remodeling. The combination of these processes causes vascular luminal narrowing and vessel obliteration that reduce pulmonary vascular surface area to the critical degree necessary for the development of the pulmonary hypertension. Cor pulmonale may be difficult to diagnose, particularly early in its course, when they symptoms manifested may be interpreted as representing progression of an underlying pathophysiological state, such as chronic obstructive airways disease. The treatment of cor pulmonale is directed toward reversing the pathogenetic process that can be directly treated, while at the same time relieving the hypoxemia, hypercapnia or acidosis. At present long-term oxygen therapy is the best treatment for pulmonary hypertension. Heart failure in cor pulmonale is usually transient once the initiating mechanism is controlled. The usual therapeutic measures for heart failure apply: a low-salt regimen, and diuretics.

  15. O universo da cor de Israel Pedrosa

    Directory of Open Access Journals (Sweden)

    Regina Lemgruber

    2004-04-01

    Full Text Available Neste novo livro, Israel Pedrosa atualiza sua teoria sobre a cor apresentada em Da cor à cor inexistente, da Editora Leo Christiano, uma referência para designers e artistas visuais há décadas (sua 7ª edição é de 1999. Em seu novo trabalho, Pedrosa fala da natureza física das cores, da visão do artista plástico em lidar com o cromatismo-com um vôo histórico sobre a história da representação pictórica-e da fisiologia da percepção visual, sem deixar de pensar a questão estética que envolve o tema.

  16. The CORS Network Products and Services

    Science.gov (United States)

    Sella, G.; Snay, R.; Cline, M.; Don, H.

    2008-12-01

    The National Geodetic Survey (NGS) is responsible for defining, providing access and maintaining the National Spatial Reference System (NSRS) which is the legally binding reference frame for the civilian sector of the US Federal Government, and most of the public. With the increasing access to space geodetic data sources, especially GPS, NGS has been transitioning to a space based NSRS. In 1994 NGS created the Continuously Operating Reference Station (CORS) network as a partnership with site operators of continuously operating GNSS sites who were willing to share their data with the public. The network currently contains ~1,200 stations, located mostly in the United States, and is growing at ~ 200 stations a year. The CORS network is particularly dense in the eastern United States, and its GPS observations are used extensively by researchers. NGS is taking a number of steps to improve its CORS related products and services including: 1) More stringent requirements for constructing new CORS as well as operating existing stations, 2) Investigating biases affecting GPS observations collected at CORS, in particular the effects of multipath, and 3) Improving processing software of GPS observables to compute orbits and coordinate computation. This effort has been emphasized because NGS is both an IGS analysis center and the current IGS analysis center coordinator. NGS is reprocessing all CORS data collected since 1994 with the goal of updating the current legally binding geometric reference frame known as NAD83. NGS has also improved and expanded its post-processing web service tools, including the Online Positioning User Service (OPUS). Lastly NGS is now operating a prototype real time GNSS data-delivery service broadcasting in RTCM format via NTRIP.

  17. CAUSES AND CLINICAL CHARACTERISTICS OF CHRONIC COR ...

    African Journals Online (AJOL)

    hi-tech

    2004-04-04

    Apr 4, 2004 ... history of paroxysms of dyspnoea and wheezing, absence of a history of cigarette smoking and adequate response to oral steroid treatment. All 15 patients had either perennial or frequent intermittent attacks of asthma. The mean duration of illness was 23 years before they developed chronic cor-pulmonale ...

  18. Cor Winkler Prins, the silent force

    NARCIS (Netherlands)

    Hoek Ostende, van den L.W.; Donovan, S.K.

    2010-01-01

    Contents - Introduction - Son of a famous family - The student years - Curator and science manager - A brachiopod life - Acknowledgements - Principal scientific publications of Cor Winkler Prins Introduction Silent respect. It is the way the Cornelius Winkler Prins treated the world, and often the

  19. 48 CFR 652.242-70 - Contracting Officer's Representative (COR).

    Science.gov (United States)

    2010-10-01

    ... Representative (COR). 652.242-70 Section 652.242-70 Federal Acquisition Regulations System DEPARTMENT OF STATE... Contracting Officer's Representative (COR). As prescribed in 642.272(a), insert a clause substantially the same as follows: Contracting Officer's Representative (COR) (AUG 1999) (a) The Contracting Officer may...

  20. 48 CFR 642.270 - Contracting Officer's Representative (COR).

    Science.gov (United States)

    2010-10-01

    ... Representative (COR). 642.270 Section 642.270 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT... Officer's Representative (COR). (a) Scope. Contracting officers may designate technically qualified... training and have the necessary experience and judgment shall be appointed as CORs. This policy shall be...

  1. Sen2Cor for Sentinel-2

    Science.gov (United States)

    Main-Knorn, Magdalena; Pflug, Bringfried; Louis, Jerome; Debaecker, Vincent; Müller-Wilm, Uwe; Gascon, Ferran

    2017-10-01

    In the frame of the Copernicus programme, ESA has developed and launched the Sentinel-2 optical imaging mission that delivers optical data products designed to feed downstream services mainly related to land monitoring, emergency management and security. The Sentinel-2 mission is the constellation of two polar orbiting satellites Sentinel-2A and Sentinel-2B, each one equipped with an optical imaging sensor MSI (Multi-Spectral Instrument). Sentinel-2A was launched on June 23rd, 2015 and Sentinel-2B followed on March 7th, 2017. With the beginning of the operational phase the constellation of both satellites enable image acquisition over the same area every 5 days or less. To use unique potential of the Sentinel-2 data for land applications and ensure the highest quality of scientific exploitation, accurate correction of satellite images for atmospheric effects is required. Therefore the atmospheric correction processor Sen2Cor was developed by Telespazio VEGA Deutschland GmbH on behalf of ESA. Sen2Cor is a Level-2A processor which main purpose is to correct single-date Sentinel-2 Level-1C Top-Of-Atmosphere (TOA) products from the effects of the atmosphere in order to deliver a Level-2A Bottom-Of-Atmosphere (BOA) reflectance product. Additional outputs are an Aerosol Optical Thickness (AOT) map, a Water Vapour (WV) map and a Scene Classification (SCL) map with Quality Indicators for cloud and snow probabilities. Telespazio France and DLR have teamed up in order to provide the calibration and validation of the Sen2Cor processor. Here we provide an overview over the Sentinel-2 data, processor and products. It presents some processing examples of Sen2Cor applied to Sentinel-2 data, provides up-to-date information about the Sen2Cor release status and recent validation results at the time of the SPIE Remote Sensing 2017.

  2. Serum soluble Fas in patients with Schistosomal cor pulmonale.

    Science.gov (United States)

    Salama, Mai; El-Kholy, Gamal; Abd El-Haleem, Soheir; Elzamarany, Enas; Abou Freikha, Mohamed; Elwan, Nadia; El-Masry, Magdy; Al-Bacil, Amr; Elhendy, Abdou

    2003-01-01

    Schistosomal cor pulmonale is considered an important pathological condition in endemic areas. Few recent studies have reported the role of apoptosis in pulmonary hypertension. The aim of this study was to assess serum levels of soluble Fas (sFas), an inhibitor of apoptosis, in patients with schistosomal cor pulmonale as compared to patients with cor pulmonale due to chronic obstructive pulmonary disease (COPD) and normal subjects. Serum sFas was assessed in 15 men with schistosomal cor pulmonale (age 32 +/- 10 years), 15 men with chronic cor pulmonale secondary to COPD and 20 healthy men, matched for age. Serum levels of sFas were significantly higher in patients with schistosomal cor pulmonale (74 +/- 80 U/ml) than in patients with cor pulmonale due to COPD (15 +/- 10 U/ml) and normal subjects (19 +/- 11 U/ml, p cor pulmonale, sFas was significantly higher in patients with mean pulmonary artery pressure > 30 mm Hg as compared to patients with pressure cor pulmonale (r = 0.4, p cor pulmonale and they are related to the severity of pulmonary hypertension. These findings suggest a role of apoptosis in schistosomal cor pulmonale. Copyright 2003 S. Karger AG, Basel

  3. Renal enlargement in chronic cor pulmonale

    Science.gov (United States)

    Ellis, P. A.

    1961-01-01

    Examination of the post-mortem records of 1,391 unselected cases showed that the commonest condition associated with excessive diffuse enlargement of the kidneys was chronic cor pulmonale. A less striking enlargement was found in some cases of chronic rheumatic heart disease. A hypothesis is put forward in which the renal enlargement is regarded as a work hypertrophy brought about by the kidneys' efforts to compensate for a chronic respiratory acidosis. Images PMID:13890003

  4. Cosmic Origins (COR) Technology Development Program Overview

    Science.gov (United States)

    Werneth, Russell; Pham, B.; Clampin, M.

    2014-01-01

    The Cosmic Origins (COR) Program Office was established in FY11 and resides at the NASA Goddard Space Flight Center (GSFC). The office serves as the implementation arm for the Astrophysics Division at NASA Headquarters for COR Program related matters. We present an overview of the Program’s technology management activities and the Program’s technology development portfolio. We discuss the process for addressing community-provided technology needs and the Technology Management Board (TMB)-vetted prioritization and investment recommendations. This process improves the transparency and relevance of technology investments, provides the community a voice in the process, and leverages the technology investments of external organizations by defining a need and a customer. Goals for the COR Program envisioned by the National Research Council’s (NRC) “New Worlds, New Horizons in Astronomy and Astrophysics” (NWNH) Decadal Survey report includes a 4m-class UV/optical telescope that would conduct imaging and spectroscopy as a post-Hubble observatory with significantly improved sensitivity and capability, a near-term investigation of NASA participation in the Japanese Aerospace Exploration Agency/Institute of Space and Astronautical Science (JAXA/ISAS) Space Infrared Telescope for Cosmology and Astrophysics (SPICA) mission, and future Explorers.

  5. Incremental value of three-dimensional over two-dimensional transthoracic echocardiography in the assessment of cor triatriatum sinister in a child.

    Science.gov (United States)

    Liao, Chung P; Hsiung, Ming C; Yuzbas, Burcu; Gok, Gulay; Sharma, Rohit; Nanda, Navin C; Chen, Fong L

    2014-05-01

    A 2.5-year-old boy presented with frequent hospitalizations due to recurrent respiratory tract infections with dyspnea. A fibromuscular membrane dividing the left atrium with obstruction of left atrial inflow to the left ventricle was documented by two-dimensional transthoracic echocardiography (2DTTE). Live/real time three-dimensional transthoracic echocardiography (3DTTE) provided incremental value over 2DTTE by providing en face views of the 2 obstructing orifices in the membrane enabling accurate assessment of their position, shape and size. 3DTTE also showed clearly the location of the membrane superior and proximal to the left atrial appendage which was not well delineated by 2DTTE. In addition, 3DTTE demonstrated the full extent of the left atrial appendage and careful sequential cropping of the 3D dataset showed it to have 2 distinct lobes and no thrombus. These findings provided comprehensive assessment of the lesion and were helpful in surgical decision making and planning. © 2014, Wiley Periodicals, Inc.

  6. Cor pulmonale in a case of infantile Gaucher's disease.

    Science.gov (United States)

    Patra, Soumya; Chatterjee, Sayan; Singhla, Shilpi; Patra, Bijoy; Maheswari, Anu; Seth, Anju

    2011-04-01

    Infantile Gaucher's disease presenting as cor pulmonale is rarely reported in pediatric literature. We report a 3.3 year old boy with infantile Gaucher's disease who presented to us as interstitial lung disease, pulmonary hypertension along with features of cor pulmonale. The high resolution CT findings were typical of interstitial and airspace disease. Cor pulmonale in this patient was a result of severe pulmonary hypertension.

  7. Isolation and expression pattern of COR15b and KIN1 genes in ...

    African Journals Online (AJOL)

    sequences of COR15b and KIN1 genes were firstly isolated from leaves of watermelon (Citrullus lanatus) and pumpkin (Cucurbita moschata). Sequencing results indicated that the open reading fragments (ORF) of COR15b in watermelon (ClCOR15b) and COR15b in pumpkin (CmCOR15b) were 348 and 426 bp, which ...

  8. Crystallographic Orientation Relationships (CORs) between rutile inclusions and garnet hosts: towards using COR frequencies as a petrogenetic indicator

    Science.gov (United States)

    Griffiths, Thomas; Habler, Gerlinde; Schantl, Philip; Abart, Rainer

    2017-04-01

    Crystallographic orientation relationships (CORs) between crystalline inclusions and their hosts are commonly used to support particular inclusion origins, but often interpretations are based on a small fraction of all inclusions in a system. The electron backscatter diffraction (EBSD) method allows collection of large COR datasets more quickly than other methods while maintaining high spatial resolution. Large datasets allow analysis of the relative frequencies of different CORs, and identification of 'statistical CORs', where certain limited degrees of freedom exist in the orientation relationship between two neighbour crystals (Griffiths et al. 2016). Statistical CORs exist in addition to completely fixed 'specific' CORs (previously the only type of COR considered). We present a comparison of three EBSD single point datasets (all N > 200 inclusions) of rutile inclusions in garnet hosts, covering three rock systems, each with a different geological history: 1) magmatic garnet in pegmatite from the Koralpe complex, Eastern Alps, formed at temperatures > 600°C and low pressures; 2) granulite facies garnet rims on ultra-high-pressure garnets from the Kimi complex, Rhodope Massif; and 3) a Moldanubian granulite from the southeastern Bohemian Massif, equilibrated at peak conditions of 1050°C and 1.6 GPa. The present study is unique because all datasets have been analysed using the same catalogue of potential CORs, therefore relative frequencies and other COR properties can be meaningfully compared. In every dataset > 94% of the inclusions analysed exhibit one of the CORs tested for. Certain CORs are consistently among the most common in all datasets. However, the relative abundances of these common CORs show large variations between datasets (varying from 8 to 42 % relative abundance in one case). Other CORs are consistently uncommon but nonetheless present in every dataset. Lastly, there are some CORs that are common in one of the datasets and rare in the remainder

  9. 48 CFR 1301.670 - Appointment of contracting officer's representative (COR).

    Science.gov (United States)

    2010-10-01

    ... officer's representative (COR). 1301.670 Section 1301.670 Federal Acquisition Regulations System..., Contracting Authority, and Responsibilities 1301.670 Appointment of contracting officer's representative (COR..., appointment and cancellation of CORs is described in CAM 1301.670. ...

  10. Trials, Tribulations, and Triumphs of a COR Mentoring Program.

    Science.gov (United States)

    Jung, John

    To increase the supply of mental health researchers from ethnic minority groups, in 1981 the National Institute of Mental Health initiated the Minority Access to Research Careers (MARC) program which was renamed Career Opportunities in Research (COR). In this paper, the Program Director of the MARC/COR Program at California State University, Long…

  11. Modeling Information-Seeking Dialogues: The Conversational Roles (COR) Model.

    Science.gov (United States)

    Sitter, Stefan; Stein, Adelheit

    1996-01-01

    Introduces a generic, application-independent model of human-computer information-seeking dialog, the Conversational Roles (COR) Model, and reviews the theoretical background. COR is represented as a recursive state-transition-network that determines legitimate types and possible sequences of dialog acts, and categorizes dialog acts on the basis…

  12. A CASE OF COR BILOCULARE ACCOMPANIED BY POLYSPLENIA

    Directory of Open Access Journals (Sweden)

    M. S. ROJHAN

    1972-07-01

    Full Text Available The clinical history and necroscopic fi ndings of a 3 -} year old girl - involved in cor biloculare was reported. In th is case dextrotransposition of the great a rteries and polysplenia was observed. The majority of cor biloculare cases appearing in the literature being accompanied by asplenia, the present case of polysplenia is relatively rare

  13. Knotworking In An Interior Décor Process

    DEFF Research Database (Denmark)

    Rasmussen, Mai; Jensen, Rasmus Lund; Fisker, Anna Marie

    2016-01-01

    These days, new buildings are being built at Aalborg University in Denmark, why interior décor processes are initiated. Planning the interior décor of Aalborg University is centralized at the Shared Service Center, where internal architects furnish the spaces and buy the selected furniture withou...

  14. Pulmonary changes and cor pulmonale in mucoviscidosis

    Science.gov (United States)

    Wentworth, Paul; Gough, Jethro; Wentworth, James E.

    1968-01-01

    The lungs of eight cases of cystic fibrosis in patients ranging from age 19 days to 23 years were examined by the large-section technique of Gough and Wentworth (Gough, 1960). All cases showed in life a susceptibility to staphylococcal and pseudomonal bronchopneumonia. In all cases the bronchial tree was plugged with mucus. The lungs from the older patients showed diffuse and pronounced bronchiectasis with luxuriant peribronchial granulation tissue and dilatation of the pulmonary arterial system. The distal air spaces in all cases showed only minimal distension and only in the eldest was there any evidence of destructive emphysema. Three cases developed cor pulmonale which we thought was the result of hypoxaemia due to a ventilation-perfusion imbalance. Images PMID:5711767

  15. Sensitivity Monitoring of the SECCHI COR1 Telescopes on STEREO

    Science.gov (United States)

    Thompson, William T.

    2018-03-01

    Measurements of bright stars passing through the fields of view of the inner coronagraphs (COR1) on board the Solar Terrestrial Relations Observatory (STEREO) are used to monitor changes in the radiometric calibration over the course of the mission. Annual decline rates are found to be 0.648 ± 0.066%/year for COR1-A on STEREO Ahead and 0.258 ± 0.060%/year for COR1-B on STEREO Behind. These rates are consistent with decline rates found for other space-based coronagraphs in similar radiation environments. The theorized cause for the decline in sensitivity is darkening of the lenses and other optical elements due to exposure to high-energy solar particles and photons, although other causes are also possible. The total decline in the COR-B sensitivity when contact with Behind was lost on 1 October 2014 was 1.7%, while COR1-A was down by 4.4%. As of 1 November 2017, the COR1-A decline is estimated to be 6.4%. The SECCHI calibration routines will be updated to take these COR1 decline rates into account.

  16. Pulmonary hypertension and chronic cor pulmonale in COPD.

    Science.gov (United States)

    Shujaat, Adil; Minkin, Ruth; Eden, Edward

    2007-01-01

    Hypoxia and endothelial dysfunction play a central role in the development of pulmonary hypertension. Cor pulmonale is a maladaptive response to pulmonary hypertension. The presence of peripheral edema in cor pulmonale is almost invariably associated with hypercapnia. Correction of abnormalities of gas exchange and ventilation can ameliorate pulmonary hypertension and improve survival. This review focuses on new information about the pathogenesis and treatment of pulmonary hypertension in COPD including information derived from lung volume reduction surgery, the role of brain natriuretic peptide, exhaled nitric oxide for diagnosis, and the treatment of cor pulmonale with recently available specific pulmonary vasodilators.

  17. 48 CFR 1352.201-72 - Contracting Officer's Representative (COR).

    Science.gov (United States)

    2010-10-01

    ... COR is also responsible for the final inspection and acceptance of all deliverables and such other... otherwise obligate the Government or authorize any changes which affect the contract price, terms or...

  18. COR V2: teaching observational research with multimedia courseware.

    Science.gov (United States)

    Blasko, Dawn G; Kazmerski, Victoria A; Torgerson, Carla N

    2004-05-01

    Courseware for Observational Research (COR Version 2) is an interactive multimedia program designed to teach the foundation of the scientific method: systematic observation. COR uses digital video with interactive coding to teach basic concepts, such as creating precise operational definitions; using frequency, interval, and duration coding; developing sampling strategies; and analyzing and interpreting data. Through lessons, a case study, and laboratory exercises, it gradually scaffolds students from teacher-directed learning into self-directed learning. The newest addition to COR is a case study in which students work collaboratively, using their own observations to make recommendations about a child's disruptive behavior in an after-school program. Evaluations of the lessons showed that classes using COR received better grades on their field observations than did those using methods that are more traditional. Students' confidence and knowledge increased as they moved through each section of the program.

  19. National Geospatial Data Asset (NGDA) Continuously Operating Reference Stations (CORS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Geodetic Survey (NGS), an office of NOAA's National Ocean Service, manages a network of Continuously Operating Reference Stations (CORS) that provide...

  20. BUSINNES MODEL OF CORS-TR (TUSAGA-AKTIF

    Directory of Open Access Journals (Sweden)

    S. Bakici

    2017-11-01

    Full Text Available CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network – Active, serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  1. Businnes Model of Cors-Tr Tusaga-Aktif

    Science.gov (United States)

    Bakici, S.; Erkek, B.; İlbey, A.; Kulaksiz, E.

    2017-11-01

    CORS-TR (TUSAGA-Aktif (Turkish National Permanent GNSS Network - Active)), serves location information at cm level accuracy in Turkey and TR Northern Cyprus in few seconds, where adequate numbers of GNSS satellites are observed and communication possibilities are present. No ground control points and benchmarks are necessary. There are 146 permanent GNSS stations within the CORS-TR System. Station data are transferred online to the main control center located in the Mapping Department of the General Directorate of Land Registry and Cadastre. CORS-TR System was established in 2008 and has been updated in software, hardware, communication and pricing areas from technical and administrative point of view in order to improve the system and provide better service to the users. Thus, the added value obtained from the CORS-TR System has been increased and contributed to the more efficient use of country resources. In this paper, how the technical, administrative and financial studies in the operation of the CORS-TR System were managed with a sustainable business model, studies for solving problems encountered in operating of the system, the cost / benefit analysis of the system and the sharing of experience gained from the perspective of how web-based applications are managed and the business model of the CORS-TR System are explained in detail.

  2. Efficacy of inhaled iloprost in cor pulmonale and severe pulmonary hypertension associated with tuberculous destroyed lung.

    Science.gov (United States)

    Park, Yae Min; Chung, Wook-Jin; Lee, Sang Pyo; Choi, Deok Young; Baek, Han Joo; Jung, Sung Hwan; Choi, In Suck; Shin, Eak Kyun

    2014-06-01

    Chronic obstructive pulmonary disease (COPD) is one of the causes of cor pulmonale. Cor pulmonale patients with pulmonary hypertension have a significant lower survival rate than patients without. However, there is no conclusive treatment options in cor pulmonale and pulmonary hypertension associated with COPD until now. We report a patient with cor pulmonale and pulmonary hypertension associated with severe form of COPD and tuberculous destroyed lung who achieved marked clinical, functional and echocardiographic hemodynamic improvements with inhaled iloprost for six months.

  3. Cor a 14: missing link in the molecular diagnosis of hazelnut allergy?

    Science.gov (United States)

    Faber, Margaretha A; De Graag, Maaike; Van Der Heijden, Catherina; Sabato, Vito; Hagendorens, Margo M; Bridts, Chris H; De Clerck, Luc S; Ebo, Didier G

    2014-01-01

    Hazelnut allergy shows distinct clinical patterns that can be predicted through component-resolved diagnosis. However, identification of sensitization profiles remains incomplete. Sera of 75 patients allergic to hazelnuts, 14 infants with atopic dermatitis (AD) sensitized to hazelnuts, 15 hazelnut-tolerant individuals with specific IgE (sIgE) to hazelnuts and 15 healthy control individuals were tested for sIgE reactivity to rCor a 1.04, rCor a 8, nCor a 9, nCor a 11, rCor a 14, rBet v 1, rBet v 2 and cross-reactive carbohydrate determinants (CCDs). Sensitization to Cor a 14 was observed in 18 out of 20 preschool children, 8 out of 10 school-aged children and 2 out of 7 adults with generalized reactions and in 3 out of 14 infants with AD. Only 2 out of 38 patients with an oral allergy syndrome (OAS) were sensitized to Cor a 14. No sensitization to Cor a 14 was observed in the group of hazelnut-tolerant and healthy control individuals. Sensitization to Cor a 1.04 was seen in 36 out of 38 OAS patients and in 14 out of 37 patients with generalized reactions. However, only 3 patients with generalized reactions were monosensitized to Cor a 1.04. Sensitization to Cor a 9 was observed in 26 out of 37 patients with generalized reactions and in 4 out of 14 infants with AD. Sensitization to Cor a 11, Cor a 8, rBet v 2 and CCDs was rare. Sensitization to Cor a 14 can have early onset and shows age-related variations. Together with Cor a 9, Cor a 14 enables us to correctly identify almost 90% of children with generalized reactions to hazelnut. © 2014 S. Karger AG, Basel.

  4. Cor triloculares biatritum with tricuspid atresia in an african child

    Directory of Open Access Journals (Sweden)

    Aliyu Ibrahim

    2014-01-01

    Full Text Available Cor triloculares biatritum is a rare congenital heart disease characterized by a three-chambered heart consisting of two atria and a single ventricle; however the case of a 5-month-old African boy who in addition to this defect had an associated tricuspid atresia and an atrial septal defect is reported.

  5. Rheumatoid interstitial lung disease presenting as cor pulmonale.

    Science.gov (United States)

    Acharya, Sourya; Mahajan, S N; Shukla, Samarth; Diwan, S K; Banode, Pankaj; Kothari, Nirmesh

    2010-10-01

    Rheumatiod arthritis (RA) is a multisystem connective tissue disorder. The predominant presentation is polyarticular, symmetric peripheral arthritis with relative sparing of axial skeleton. Inflammatory synovitis is the pathologic hallmark. Extra-articular manifestations of RA can involve several other organ systems and amongst them pulmonary manifestations occur commonly. We report a case of rheumatoid interstitial lung disease presenting as cor pulmonale.

  6. Rheumatoid interstitial lung disease presenting as cor pulmonale

    Directory of Open Access Journals (Sweden)

    Acharya Sourya

    2010-01-01

    Full Text Available Rheumatiod arthritis (RA is a multisystem connective tissue disorder. The predominant presentation is polyarticular, symmetric peripheral arthritis with relative sparing of axial skeleton. Inflammatory synovitis is the pathologic hallmark. Extra-articular manifestations of RA can involve several other organ systems and amongst them pulmonary manifestations occur commonly. We report a case of rheumatoid interstitial lung disease presenting as cor pulmonale.

  7. Isolation and expression pattern of COR15b and KIN1 genes in ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-11-02

    Nov 2, 2009 ... COR15b and KIN1 (COR 6.5) genes encode polypeptides of 15 KDa and 6.5 KDa, respectively. They are involved in the dehydration tolerance mechanisms and play important role under cold stress. cDNA sequences of COR15b and KIN1 genes were firstly isolated from leaves of watermelon (Citrullus.

  8. Transient Expression of cor Gene in Papaver somniferum

    Directory of Open Access Journals (Sweden)

    Bahman Hosseini

    2011-12-01

    Full Text Available Introduction: Papaver somniferum is the commercial source of morphine and codeine. The isolation of effective genes involved in the morphine biosynthesis of P. somniferum is very important in the production of specific metabolites achieved using metabolic engineering techniques. In this pathway, the key enzyme COR is involved in the conversion of codeinone to codeine and morphinone to morphine. Methods: the gene encoding of this enzyme was isolated using primers designed on the base of gene sequence available on (NCBI for P. somniferum. This gene correct size around (960 bp was first subcloned into pTZ57RIT vector then cloned into expression vectors (pBI121 between BamHI and SacI sites to allow the expression of cor gene driven by the cauliflower mosaic virus 35S promoter. The result was confirmed through different molecular methods e.g. PCR and enzyme digestion by BamHI and SacI. The recombinant plasmid was transformed into the E. coli strain DH5α using a freeze-thaw method. Having selected positive colones on selection medium, plasmid was extracted by miniprep method and recombinant plasmids were selected based on PCR and digestion. The construct was then mobilized in Agrobacterium tumefaciens C58/pGV3850 (KmR RifR. After gene transformation to P. somniferum plants, the agroinfiltration method was also used for transient expression of COR enzyme. Results: evaluation results showed that morphine and codeine were detectable in the leaves of transgenic plants containing cor transgene and there was significant difference in the final production. After completing this experiment for three times, results showed that in 11 sets from 15 sets of leaves experiment tested, main alkaloids (codeine, morphine, papaverin, noscapine and thebaine were detectable. Conclusion: Whereas no signal was detected in non-infiltrated control leaves or in leaves infiltrated with non-recombinant bacteria for morphine and codeine, others such as thebaine and papaverine

  9. Averroes y su uso de aleyas coránicas

    Directory of Open Access Journals (Sweden)

    Josep Puig Montada

    2013-06-01

    Full Text Available El artículo considera el uso que hace Averroes de las citas coránicas en sus obras, y establece diferentes categorías. En la primera se encuentra su obra teológica cuyo título se puede traducir como Los métodos de las pruebas en las doctrinas de la religión, donde las aleyas son la base de estas doctrinas. A la segunda pertenece su comentario medio a la Retórica donde el Corán es citado por ser un modelo literario. La tercera situación es ante todo la de su obra “Tratado definitivo”, la cual tiene forma de dictamen jurídico (fatwâ. La última situación es la de obras filosóficas donde Averroes cita aleyas coránicas para su interpretación de Aristóteles.

  10. Cor pulmonale in a case of infantile Gaucher′s disease

    Directory of Open Access Journals (Sweden)

    Soumya Patra

    2011-01-01

    Full Text Available Infantile Gaucher′s disease presenting as cor pulmonale is rarely reported in pediatric literature. We report a 3.3 year old boy with infantile Gaucher′s disease who presented to us as interstitial lung disease, pulmonary hypertension along with features of cor pulmonale. The high resolution CT findings were typical of interstitial and airspace disease. Cor pulmonale in this patient was a result of severe pulmonary hypertension.

  11. The specific characteristics in children with obstructive sleep apnea and cor pulmonale.

    Science.gov (United States)

    Lee, Pi-Chang; Hwang, Betau; Soong, Wen-Jue; Meng, C C Laura

    2012-01-01

    The prevalence of obstructive sleep apnea (OSA) in the pediatric population is currently estimated at 1-2% of all children. The purpose of this study was to investigate the clinical and hemodynamic characteristics in pediatric patients with cor pulmonale and OSA. Thirty children with the diagnosis of OSA were included. These patients consisted of 26 male and 4 female children with a mean age of 7 ± 4 years old. Five of those children were found to be associated with cor pulmonale, and 25 had OSA but without cor pulmonale. The arousal index was much higher in children with OSA and cor pulmonale. The children with OSA and cor pulmonale had much lower mean and minimal oxygen saturation and a higher incidence of bradycardia events. All 5 patients with OSA and cor pulmonale underwent an adenotonsillectomy, and the pulmonary arterial pressure dropped significantly after the surgery. This study demonstrated that the OSA pediatric patients with cor pulmonale had the different clinical manifestations and hemodynamic characteristics from those without cor pulmonale. The adenotonsillectomy had excellent results in both the OSA pediatric patients with and without cor pulmonale.

  12. Prevalence and prognosis of cor pulmonale during protective ventilation for acute respiratory distress syndrome.

    Science.gov (United States)

    Boissier, Florence; Katsahian, Sandrine; Razazi, Keyvan; Thille, Arnaud W; Roche-Campo, Ferran; Leon, Rusel; Vivier, Emmanuel; Brochard, Laurent; Vieillard-Baron, Antoine; Brun-Buisson, Christian; Mekontso Dessap, Armand

    2013-10-01

    Pulmonary vascular dysfunction is common during acute respiratory distress syndrome (ARDS), but there is controversy concerning prevalence and prognosis of cor pulmonale during protective ventilation for ARDS. This was a prospective observational study in an academic medical intensive care unit in France. Two hundred and twenty-six consecutive patients with moderate to severe ARDS (Berlin definition) ventilated with plateau pressure limited at 30 cmH₂O (mean PEEP of 8.8 ± 3.6 cmH₂O) underwent transesophageal echocardiography (TEE) within the first 3 days after the diagnosis of ARDS. Cor pulmonale was defined as a dilated right ventricle associated with septal dyskinesia. Cor pulmonale was detected in 49 patients (prevalence of 22%; 95% confidence interval, 16-27%). Multivariate logistic regression identified infectious causes of lung injury and higher driving pressures as independent factors associated with cor pulmonale. Patients with cor pulmonale exhibited a higher incidence of shock (need for vasoactive drug) at the time of TEE and were more often managed with prone positioning and/or nitric oxide as adjunctive therapy for severe hypoxemia during ARDS course. The 28-day mortality rate was significantly higher in the group with cor pulmonale (60 vs. 36%, p cor pulmonale as independent risk factors for 28-day mortality. Cor pulmonale occurrence is not negligible in ARDS patients ventilated with airway pressure limitation. Cor pulmonale was associated with sepsis and higher values of driving pressure and was an independent risk factor for 28-day mortality in our series.

  13. The Specific Characteristics in Children with Obstructive Sleep Apnea and Cor Pulmonale

    Directory of Open Access Journals (Sweden)

    Pi-Chang Lee

    2012-01-01

    Full Text Available Background. The prevalence of obstructive sleep apnea (OSA in the pediatric population is currently estimated at 1-2% of all children. The purpose of this study was to investigate the clinical and hemodynamic characteristics in pediatric patients with cor pulmonale and OSA. Methods. Thirty children with the diagnosis of OSA were included. These patients consisted of 26 male and 4 female children with a mean age of 7 ± 4 years old. Five of those children were found to be associated with cor pulmonale, and 25 had OSA but without cor pulmonale. Results. The arousal index was much higher in children with OSA and cor pulmonale. The children with OSA and cor pulmonale had much lower mean and minimal oxygen saturation and a higher incidence of bradycardia events. All 5 patients with OSA and cor pulmonale underwent an adenotonsillectomy, and the pulmonary arterial pressure dropped significantly after the surgery. Conclusion. This study demonstrated that the OSA pediatric patients with cor pulmonale had the different clinical manifestations and hemodynamic characteristics from those without cor pulmonale. The adenotonsillectomy had excellent results in both the OSA pediatric patients with and without cor pulmonale.

  14. Adenotonsillar hypertrophy and cor pulmonale: clinical and echocardiographic correlation.

    Science.gov (United States)

    Kumar, E. B.; Jaggarao, N. S.

    1989-01-01

    It is well recognized that upper airways obstruction by adenotonsillar hypertrophy can lead to cor pulmonale, but delays in diagnosis still occur, leading to an appreciable morbidity and even occasional mortality. In the case presented, echocardiographic recognition of right ventricular enlargement and abnormal pulmonary valve motion served to complement and confirm the clinical diagnosis. Following surgical relief of the airways obstruction, the echocardiographic examination usefully documented the regression in right ventricular size and the return to normality of pulmonary valve motion. Images Figure 1 Figure 2 PMID:2602239

  15. Modulation of monocrotaline-induced cor pulmonale by grape juice.

    Science.gov (United States)

    Ludke, Ana R L; Mosele, Francisca; Caron-Lienert, Rafaela; Ribeiro, Maria Flávia; Partata, Wânia; Llesuy, Susana; Araujo, Alex Sander; Singal, Pawan; Belló-Klein, Adriane

    2010-01-01

    The study was designed to test whether the ingestion grape juice (GJ) could modulate monocrotaline (MCT)-induced Cor pulmonale resulting from antioxidant properties. Three-week-old male Wistar rats received GJ (10 mL/kg/day) by gavage for 6 weeks. A single injection of MCT (60 mg/kg body weight intraperitoneally) was administered at the end of the third week. Animals were divided in four groups: control, MCT, GJ, and GJ + MCT. MCT promoted a significant increase in right ventricle (36%) and lung (70%) weight to body weight ratio. There was an increase in the right systolic (38%) as well as in the end diastolic (70%) ventricular pressures. MCT caused a significant decrease in lung endothelial nitric oxide synthase (20%) but increase in lipid peroxidation (13%) and catalase (43%). MCT-induced decrease in the endothelial nitric oxide synthase and increase in the right ventricular end diastolic pressure were prevented by GJ, whereas right systolic ventricular pressure and lung weight to body weight ratio were corrected only partially. MCT-induced increase in heart and right ventricle to body weight ratios was not changed by GJ. GJ blunted MCT-induced increase in lipid peroxidation but had no effect on the changes in catalase and superoxide dismutase activities. GJ appears to offer some protection against MCT-induced Cor pulmonale and right ventricle function changes.

  16. Investigation of accurate method in 3-D position using Cors-Net in Istanbul

    Directory of Open Access Journals (Sweden)

    Kutalmis Gumus

    Full Text Available In this study, for Istanbul, there are two Cors Networks (Cors-TR, Iski Cors providing Virtual Reference Station (VRS, and Flachen Korrektur Parameter (FKP, corrections to rover receiver for determining 3-D positions in real time by Global Positioning System (GPS. To determine which method (or technique provides accurate method for position fixing, a test network consisting of 49 stations was set up in Yildiz Technical University Davudpasa Campus. The coordinates of the stations in the test network were determined by conventional geodetic, classical RTK, VRS and FKP methods serviced by both Cors-TR and Iski Cors. The results were compared to the coordinates by the conventional method by using total station. The results showed a complex structure as the accuracy differs from one component to another such as in horizontal coordinates, Y components by CorsTR_VRS and Cors_TR_ FKP showed 'best' results while the same technique provided X components consistent accuracy with the Y component but less accurate than by real time kinematic (RTK. In vertical components, of all the techniques used for the h components, CorsTR_VRS showed 'best' accuracy with three outliers.

  17. Involvement of SGT1 in COR-mediated signal transduction pathway leading to disease symptom development.

    Science.gov (United States)

    Ishiga, Yasuhiro; Uppalapati, Srinivasa Rao; Ishiga, Takako; Mysore, Kirankumar S

    2011-07-01

    Pseudomonas syringae pv. tomato DC3000 (Pst DC3000), that causes bacterial speck disease on tomato, produces a non-host-specific virulence effector, coronatine (COR). COR functions as a jasmonic acid (JA)-isoleucine mimic in planta and has multiple roles in the pathogenicity of Pst DC3000. One of the hallmarks of bacterial speck disease on tomato is the formation of necrotic lesions surrounded by chlorosis and COR is required for disease development. However, the molecular basis of COR-mediated disease symptom development including chlorosis and necrosis is still largely unknown. In our recent publication in New Phytologist, using virus-induced gene silencing (VIGS) based reverse genetics screen, we demonstrated that SGT1 (suppressor of G2 allele of skp1) is required for COR-induced chlorosis in Nicotiana benthamiana. SGT1-silenced tomato leaves showed a complete loss of COR-induced chlorosis and reduced disease symptom development after the inoculation with Pst DC3000. Furthermore, Arabidopsis sgt1b mutant was less sensitive to COR-induced root growth inhibition and showed delayed Pst DC3000 disease symptoms. In this addendum, we discuss the possible contribution of SGT1 to COR-mediated signal transduction pathway leading to disease symptom development during Pst DC3000 pathogenesis in tomato and Arabidopsis.

  18. Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01

    DEFF Research Database (Denmark)

    Lüttkopf, D; Müller, U; Skov, P S

    2002-01-01

    -blind placebo-controlled food challenges (DBPCFC) in a multicenter study. Total RNA was isolated from immature hazelnuts and transcribed into cDNA. Full length coding DNA obtained by PCR-strategy was subcloned into pTYB11 vector and expressed in E. coli ER2566 cells. Native non-fusion target proteins were...... purified by DTT-induced self-cleavage of the intein-tagged N-terminal fusion proteins. IgE reactivity of the recombinant allergens was tested by enzyme allergosorbent test (EAST), EAST-inhibition, immunoblot-inhibition and histamine release assays. Four recombinant allergens were produced showing deduced...... amino acid sequence identities among each other of 97-99%, and were considered as variants Cor a 1.0401 (GenBank Accession no.: AF136945), Cor a 1.0402 (AF323973), Cor a 1.0403 (AF323974) and Cor a 1.0404 (AF323975). Cor a 1.0402 and 03 only differed in a C4S exchange. Cor a 1.0404 had a unique proline...

  19. Deletions, duplications and transpositions of the COR segment that encompasses the structural gene of yeast iso-1-cytochrome c

    Energy Technology Data Exchange (ETDEWEB)

    Stiles, J.I.; Friedman, L.R.; Sherman, F.

    1980-01-01

    It has been recently found that a specific chromosomal segment, in certain but not all laboratory strains of Saccharomyces cerevisiae, is deleted and transposed at high frequencies. This segment, denoted COR, encompasses the three closely linked loci CYC1, OSM1 and RAD7 which control iso-1-cytochrome c, osmotic sensitivity and UV-sensitivity, respectively. Two types of apparently normal laboratory strains of yeast designated COR1 and COR2, were uncovered after the examination of the frequencies and types of mutations causing either deficiencies or overproduction of iso-1-cytochrome c; in contrast to COR1 strains which give predominantly point mutations causing deficiencies of iso-1-cytochrome c, COR2 strains give rise to deletions and transpositions of the COR segment. We have undertaken a systematic investigation of the physical structure and genetic properties of the COR region and of the aberrations arising in COR2 strains.

  20. Combined spinal-epidural anesthesia for cesarean delivery in a patient with cor triloculare biventriculare.

    Science.gov (United States)

    Han, Yuan; Zhang, Zhenfeng; Sun, Qingchun; Ding, Ke; Han, Liu; Dong, Mengmeng; Xu, Yifan; Ge, Lei

    2017-08-29

    Cor triloculare biventriculare accounts for approximately 0.31% of cases of congenital heart disease (CHD). Moreover, people with cor triloculare biventriculare always have shorter life spans, and cases of gestation are rare. There have been various related reports of cor triloculare biventriculare in recent years. We described an emergency cesarean section of a 30-year-old, 38-weeks-pregnant woman suffering from cardiac insufficiency and fetal distress. Combined spinal-epidural anesthesia was performed safely, and a male baby was smoothly delivered 10 min after the procedure without any adverse outcome on the mother or newborn. After surgery, we advised that the patient submit to an echocardiogram examination, which revealed the congenital heart disease cor triloculare biventriculare. Combined spinal-epidural anesthesia was administered to a patient with cor triloculare biventricularethis with good effect, ensuring the patient's safety and meeting the need for emergency surgery.

  1. Structural and Functional Characterization of the Hazelnut Allergen Cor a 8.

    Science.gov (United States)

    Offermann, Lesa R; Bublin, Merima; Perdue, Makenzie L; Pfeifer, Sabine; Dubiela, Pawel; Borowski, Tomasz; Chruszcz, Maksymilian; Hoffmann-Sommergruber, Karin

    2015-10-21

    Nonspecific lipid transfer proteins (nsLTPs) are basic proteins, stabilized by four disulfide bonds, and are expressed throughout the plant kingdom. These proteins are also known as important allergens in fruits and tree nuts. In this study, the nsLTP from hazelnuts, Cor a 8, was purified and its crystal structure determined. The protein is stable at low pH and refolds after thermal denaturation. Molecular dynamics simulations were used to provide an insight into conformational changes of Cor a 8 upon ligand binding. When known epitope areas from Pru p 3 were compared to those of Cor a 8, differences were obvious, which may contribute to limited cross-reactivity between peach and hazelnut allergens. Differences in epitope regions may contribute to limited cross-reactivity between Cor a 8 and nsLTPs from other plant sources. The structure of Cor a 8 represents the first resolved structure of a hazelnut allergen.

  2. Strategic planning of INA-CORS development for public service and tectonic deformation study

    Science.gov (United States)

    Syetiawan, Agung; Gaol, Yustisi Ardhitasari Lumban; Safi'i, Ayu Nur

    2017-07-01

    GPS technology can be applied for surveying, mapping and research purposes. The simplicity of GPS technology for positioning make it become the first choice for survey compared with another positioning method. GPS can measure a position with various accuracy level based on the measurement method. In order to facilitate the GPS positioning, many organizations are establishing permanent GPS station. National Geodetic Survey (NGS) called it as Continuously Operating Reference Stations (CORS). Those devices continuously collect and record GPS data to be used by users. CORS has been built by several government agencies for particular purposes and scattered throughout Indonesia. Geospatial Information Agency (BIG) as a geospatial information providers begin to compile a grand design of Indonesia CORS (INA-CORS) that can be used for public service such as Real Time Kinematic (RTK), RINEX data request, or post-processing service and for tectonic deformation study to determine the deformation models of Indonesia and to evaluate the national geospatial reference system. This study aims to review the ideal location to develop CORS network distribution. The method was used is to perform spatial analysis on the data distribution of BIG and BPN CORS overlayed with Seismotectonic Map of Indonesia and land cover. The ideal condition to be achieved is that CORS will be available on each radius of 50 km. The result showed that CORS distribution in Java and Nusa Tenggara are already tight while on Sumatra, Celebes and Moluccas are still need to be more tighten. Meanwhile, the development of CORS in Papua will encounter obstacles toward road access and networking. This analysis result can be used as consideration for determining the priorities of CORS development in Indonesia.

  3. PENGARUH CHILLER PENDINGIN PADA KEKERASAN PRODUK COR PROPELER ALUMUNIUM

    Directory of Open Access Journals (Sweden)

    Hera Setiawan

    2014-11-01

    Full Text Available ABSTRAK Penelitian ini merupakan pengembangkan proses pembekuan searah (unidirectional solidifications sehingga dihasilkan struktur columnar dendrite pada pengecoran alumunium propeler kapal nelayan untuk meningkatkan sifat mekanis material. Pengecoran dilakukan dengan pasir cetak (sand casting dan proses peleburan logam dilakukan pada dapur crusible dengan bahan bakar minyak. Teknik pengecoran dilakukan dengan pendinginan logam cor dengan chiller pendingin yang dialiri air dengan dorongan pompa. Pengujian spectrometer digunakan untuk mengetahui komposisi kimia material alumunium. Pengujian kekerasan digunakan metode Rockwell dengan indentor bola baja diameter 1/16 inchi dengan beban mayor 100 kg (HRB. Hasil penelitian ini menunjukkan bahwa teknik pembekuan searah dengan chiller pendingin dapat meningkatkan kekerasan material alumunium propeler sebesar 3,99% dari 60,5 HRB menjadi 62,9 HRB. Kata kunci: alumunium, propeler, chiller, kekerasan, pembekuan searah.

  4. Pulmonary embolism and cor pulmonale in a cat

    International Nuclear Information System (INIS)

    Sottiaux, J.; Franck, M.

    1999-01-01

    A 14-year-old male neutered cat experienced pulmonary embolism 15 days following surgical debridement of a recurrent dorsolumbar abscess. Clinical signs were dominated by respiratory distress. Pulmonary embolism was suggested from the lateral thoracic radiograph by the presence of an abruptly attenuated lobar artery and a contiguous oligaemic area in the caudal lung lobe. Pulmonary hypertension was demonstrated on Doppler echocardiography by right pulmonary artery dilation and tricuspid regurgitation raising the pulmonary arterial pressure to 56 mmHg. Chronic pulmonary hypertension, assumed from right ventricular wall hypertrophy, and hypokinesia, indicating chronic cor pulmonale, was suggestive of chronic rather than acute pulmonary embolism. Postmortem histological evidence of pulmonary arteriolar occlusion confirmed the diagnosis of pulmonary embolism

  5. [Acute cor pulmonale in acute respiratory distress syndrome].

    Science.gov (United States)

    Zhang, Feng; Cao, Quan; Zuo, Xiangrong

    2017-03-01

    Acute respiratory distress syndrome (ARDS) is a severe respiratory condition that is characterized by rapidly progressive hypoxemia with noncardiogenic pulmonary edema. Despite the improvement of therapeutic methods, the mortality of ARDS is in the range of 40%-50% all over the world. Some studies have shown that a significant number of patients with ARDS had acute cor pulmonale (ACP), and ACP is independently associated with the mortality of patients with ARDS, which has attracted wide attention in recent years. This paper reviewed recent related studies, summarized the prevalence, pathogenesis and diagnostic approaches of ACP in ARDS, especially echocardiography which was considered as a cornerstone for ACP diagnosis, and elucidated the beneficial effects of right ventricular protective ventilatory strategy and prone-positioning on the pulmonary vasculature and right heart, in order to provide a novel idea for the therapy of ACP in ARDS.

  6. Cor Pulmonale Revisited. From Ferrer and Harvey to the Present.

    Science.gov (United States)

    Rubin, Lewis J

    2018-02-01

    The term cor pulmonale has traditionally been used as a synonym for right heart failure due to chronic respiratory diseases, although this condition is less frequently seen in the modern era because of the use of long-term oxygen therapy along with aggressive measures directed at optimizing ventilation and gas exchange. The mechanisms by which adaptation or maladaptation of right heart structure and function in the broader setting of pulmonary vascular disease, either intrinsic to the pulmonary circulation or due to respiratory diseases, have garnered considerable interest along with the development of medical and surgical treatments for pulmonary hypertension. Thus, the right heart is no longer considered an "innocent bystander" in pulmonary hypertension, but rather a key component in its pathophysiology. Furthermore, the status of right heart function is a major determinant of outcome. Accordingly, the right heart has become a potential, appealing target for novel therapies to treat hypertensive pulmonary vascular disease.

  7. Impaired theophylline clearance in patients with cor pulmonale.

    Science.gov (United States)

    Vicuna, N; McNay, J L; Ludden, T M; Schwertner, H

    1979-01-01

    1 The relationship between serum theophylline concentration and daily dose was studied in 45 patients receiving aminophylline orally and in 36 patients receiving it by constant intravenous infusion. 2 Patients were categorized as uncomplicated chronic obstructive pulmonary disease (COPD) or COPD with cor pulmonale (CP). 3 Serum theophylline concentration relative to daily theophylline dose was significantly higher in patients with COPD plus CP than in patients with COPD alone. 4 Total body clearance of theophylline estimated from data obtained during constant intravenous infusion was significantly lower in COPD plus CP than in patients with COPD alone. 5 We conclude that reduced maintenance doses of theophylline are indicated in patients with COPD when complicated with CP. PMID:760740

  8. A case of pulmonary alveolar microlithiasis with Cor Pulmonale.

    Science.gov (United States)

    Chen, Wen; Gu, Tao

    2012-03-01

    Pulmonary alveolar microlithiasis (PAM) is a rare disease characterized by the formation and deposition of microliths within the alveoli and a paucity of symptoms in contrast to the imaging findings. It has familial tendency and is thought to be an autosomal recessive disorder with the mutation in the SLC34A2 gene. We describe a case of PAM with Cor Pulmonale. Ultrasonic cardiogram showed pulmonary hypertension (82 mmHg). Chest radiography revealed diffuse, bilateral sandstorm-like micronodules with greater density in the lower lung fields. HRCT scans demonstrated diffuse ground-grass opacities, thickening and calcification of interlobular septa and confluent calcified nodules. A diagnosis of PAM was suggested and confirmed by transbronchial lung biopsy (TBLB).

  9. Development of the cat-owner relationship scale (CORS).

    Science.gov (United States)

    Howell, Tiffani J; Bowen, Jonathan; Fatjó, Jaume; Calvo, Paula; Holloway, Anna; Bennett, Pauleen C

    2017-08-01

    Characteristics of the human-animal bond can be influenced by both owner-related and pet-related factors, which likely differ between species. Three studies adapted the Monash Dog-Owner Relationship Scale (MDORS) to permit assessment of human-cat interactions as perceived by the cat's owner. In Study 1293 female cat owners completed a modified version of the MDORS, where 'dog' was replaced with 'cat' for all items. Responses were compared with a matched sample of female dog owners. A partial least squares discriminant analysis revealed systematic differences between cat and dog owners in the Dog (Cat)-Owner Interaction subscale (MDORS subscale 1), but not for Perceived Emotional Closeness or Perceived Costs (Subscales 2 and 3). Study 2 involved analysis of free-text descriptions of cat-owner interactions provided by 61 female cat owners. Text mining identified key words which were used to create additional questions for a new Cat-Owner Interaction subscale. In Study 3, the resulting cat-owner relationship scale (CORS) was tested in a group of 570 cat owners. The main psychometric properties of the scale, including internal consistency and factor structure, were evaluated. We propose that this scale can be used to accurately assess owner perceptions of their relationship with their cat. A modified scale, combining items from the CORS and MDORS (a C/DORS), is also provided for when researchers would find it desirable to compare human-cat and human-dog interactions. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. An orthologue of the cor gene is involved in the exclusion of temperate lambdoid phages. Evidence that Cor inactivates FhuA receptor functions

    International Nuclear Information System (INIS)

    Uc-Mass, Augusto; Loeza, Eva Jacinto; Garza, Mireya de la; Guarneros, Gabriel; Hernandez-Sanchez, Javier; Kameyama, Luis

    2004-01-01

    A new set of lambdoid phages (mEp) classified into different immunity groups was previously described. Phages mEp213, mEp237, and mEp410 were unable to grow in mEp167 lysogenic cells, presumably due to an exclusion mechanism expressed constitutively by the mEp167 repressed prophage. In this work, to analyze the exclusion phenomenon, we constructed a genomic library from mEp167 phage in a pPROEX derivative plasmid. A DNA fragment containing an open reading frame for a 77 amino acid polypeptide was selected by its ability to confer resistance to heteroimmune phage infection. This ORF shows high amino acid sequence identity with putative Cor proteins of phages HK022, φ80 and N15. Cells expressing the mEp167 cor gene from a plasmid (Cor + phenotype) excluded 13 of 20 phages from different infection immunity groups. This exclusion was observed in both tonB - and tonB + cells. Lambdoid mEp phages that were excluded in these cells were unable to infect cells defective in the outer membrane FhuA receptor (fhuA - ). Thus, Cor-mediated exclusion was only observed in fhuA + cells. Phage production after DNA transfection or the spontaneous induction of mEp prophage in Cor + cells was not blocked. In addition, ferrichrome uptake, which is mediated by FhuA, was inhibited in Cor + cells. Our results show that not only phage infection via FhuA but also a FhuA transport activity (ferrichrome uptake) are inhibited by Cor, presumably by inactivation of FhuA

  11. OpenCOR: a modular and interoperable approach to computational biology

    Directory of Open Access Journals (Sweden)

    Alan eGarny

    2015-02-01

    Full Text Available Computational biologists have been developing standards and formats for nearly two decades, with the aim of easing the description and exchange of experimental data, mathematical models, simulation experiments, etc. One of those efforts is CellML (cellml.org, an XML-based markup language for the encoding of mathematical models.Early CellML-based environments include COR and OpenCell. However, both of those tools have limitations and were eventually replaced with OpenCOR (opencor.ws. OpenCOR is an open source modeling environment that is supported on Windows, Linux and OS X. It relies on a modular approach, which means that all of its features come in the form of plugins. Those plugins can be used to organize, edit, simulate and analyze models encoded in the CellML format.We start with an introduction to CellML and two of its early adopters, which limitations eventually led to the development of OpenCOR. We then go onto describing the general philosophy behind OpenCOR, as well as describing its openness and its development process. Next, we illustrate various aspects of OpenCOR, such as its user interface and some of the plugins that come bundled with it (e.g. its editing and simulation plugins. Finally, we discuss some of the advantages and limitations of OpenCOR before drawing some concluding remarks.

  12. A ten-year review of chronic cor pulmonale secondary to respiratory diseases in Ghana.

    Science.gov (United States)

    Oduro-Boatey, Collins; Adzosii, Della

    2017-10-01

    Chronic cor pulmonale is defined as right ventricular failure secondary to pulmonary hypertension. Our study reviewed all cases of chronic cor pulmonale secondary to respiratory diseases in a ten-year period (2004-20014) in the Department of Child Health, Korle-Bu Teaching Hospital, Ghana. Nine cases of chronic cor pulmonale were recorded during the period. The age range was 1-9 years (average age = 3 years). Obstructive sleep apnoea secondary to adenoid hypertrophy was the commonest cause of pulmonary hypertension.

  13. Impacto da quantidade de água na cor de uma antocianidina (Luteolinidina

    OpenAIRE

    Tavares, Manuella Brito

    2015-01-01

    A luteolinidina é um corante natural responsável pela cor do sorgo, da família das antocianidinas e antocianinas responsáveis pela cor vermelha de alguns frutos silvestres tais como o morango e a framboesa. O objetivo principal deste trabalho foi verificar o impacto da remoção de água na cor da luteolinidina usando como modelo misturas de solvente orgânico/água a diferentes pHs, para simular a mudança de polaridade durante a secagem. Os estudos efetuados por espectroscopia de absorção U...

  14. Clinical course of cor pulmonale investigated after an interval of one year by thallium-201 myocardial SPECT scintigraphy

    Energy Technology Data Exchange (ETDEWEB)

    Yamaoka, Shimpachi; Nishimura, Kouichi; Kuno, Kenshi; Yonekura, Yoshiharu; Koide, Harutoshi.

    1988-06-01

    Cor pulmonale was evaluated in 13 patients with chronic lung disease by thallium-201 myocardial SPECT scintigraphy together with pulmonary function tests and right heart catheterization. One year later, we performed this scintigraphy again to investigate the clinical course of the cor pulmonale. In 6 of 13 patients with respiratory failure (Pao/sub 2/ less than 60 Torr), a remarkable progression in cor pulmonale was noted after one year, despite outpatient oxygen therapy. If the patients were admitted because of acute exacerbation of respiratory failure, the cor pulmonale was found to have worsened. In contrast, patients with acute exacerbation due to respiratory infection or causes other than respiratory failure, showed little change in cor pulmonale. Although patients with a marked progression of cor pulmonale tended to have poor pulmonary function data and elevated pulmonary arterial pressure, the clinical course of cor pulmonale could not be predicted from the initial pulmonary function tests or right heart catheterization.

  15. [Atypical form of cor triatrium in a 59-year-old man].

    Science.gov (United States)

    Aboukhoudir, F; Aboukhoudir, I; Rica, O; Khennine, B; Pansieri, M; Rekik, S

    2016-11-01

    Cor triatrium is a rare congenital heart disease typically diagnosed amongst very young patients. Delayed diagnosis in the elderly is much more unusual. We report the case of a 59-year-old male with unremarkable medical history in whom we have discovered, on an echocardiography performed for an exploration of transient ischemic accident with atrial fibrillation, a particular form of an isolated cor triatrium dextrum investigated with multimodality imaging. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  16. Geospatial Data Quality of the Servir CORS Network

    Science.gov (United States)

    Santos, J.; Teodoro, R.; Mira, N.; Mendes, V. B.

    2015-08-01

    The SERVIR Continuous Operation Reference Stations (CORS) network was implemented in 2006 to facilitate land surveying with Global Navigation Satellite Systems (GNSS) positioning techniques. Nowadays, the network covers all Portuguese mainland. The SERVIR data is provided to many users, such as surveyors, universities (for education and research purposes) and companies that deal with geographic information. By middle 2012, there was a significant change in the network accessing paradigm, the most important of all being the increase in the responsibility of managing the network to guarantee a permanent availability and the highest quality of the geospatial data. In addition, the software that is used to manage the network and to compute the differential corrections was replaced by a new software package. These facts were decisive to perform the quality control of the SERVIR network and evaluate positional accuracy. In order to perform such quality control, a significant number of geodetic monuments spread throughout the country were chosen. Some of these monuments are located in the worst location regarding the network geometry in order to evaluate the accuracy of positions for the worst case scenarios. Data collection was carried out using different GNSS positioning modes and were compared against the benchmark positions that were determined using data acquired in static mode in 3-hour sessions. We conclude the geospatial data calculated and provided to the users community by the network is, within the surveying purposes, accurate, precise and fits the needs of those users.

  17. Contribution of GNSS CORS Infrastructure to the Mission of Modern Geodesy and Status of GNSS CORS in Thailand

    Directory of Open Access Journals (Sweden)

    Chalermchon Satirapod

    2011-01-01

    Full Text Available Geodesy is the science of measuring and mapping the geometry, orientation and gravity field of the Earth including the associated variations with time. Geodesy has also provided the foundation for high accuracy surveying and mapping. Modern Geodesy involves a range of space and terrestrial technologies that contribute to our knowledge of the solid earth, atmosphere and oceans. These technologies include: Global Positioning System/Global Navigation Satellite Systems (GPS/GNSS, Satellite Laser Ranging (SLR, Very Long Baseline Interferometry (VLBI, Satellite Altimetry, Gravity Mapping Missions such as GRACE, CHAMP and GOCE, satelliteborne Differential Interferometric Synthetic Aperture Radar (DInSAR, Absolute and Relative Gravimetry, and Precise Terrestrial Surveying (Levelling and Traversing. A variety of services have been established in recent years to ensure high accuracy and reliable geodetic products to support geoscientific research. The reference frame defined by Modern Geodesy is now the basis for most national and regional datums. Furthermore, the GPS/GNSS technology is a crucial geopositioning tool for both Geodesy and Surveying. There is therefore a blurring of the distinction between geodetic and surveying GPS/GNSS techniques, and increasingly the ground infrastructure of continuously operating reference stations (CORS receivers attempts to address the needs of both geodesists and other positioning professionals. Yet Geodesy is also striving to increase the level of accuracy by a factor of ten over the next decade in order to address the demands of “global change” studies. The Global Geodetic Observing System (GGOS is an important component of the International Association of Geodesy. GGOS aims to integrate all geodetic observations in order to generate a consistent high quality set of geodetic parameters for monitoring the phenomena and processes within the “System Earth”. Integration implies the inclusion of all relevant

  18. Clinical and morphologic features of acute, subacute and chronic cor pulmonale (pulmonary heart disease).

    Science.gov (United States)

    Roberts, William Clifford; Shafii, Alexis E; Grayburn, Paul A; Ko, Jong Mi; Weissenborn, Matthew R; Rosenblatt, Randall L; Guileyardo, Joseph M

    2015-03-01

    Described are certain clinical and morphologic features of one patient with acute, another with subacute, and one with chronic cor pulmonale. All 3 had evidence of severe pulmonary hypertension. The patient with acute cor pulmonale 4 days after coronary bypass for unstable angina pectoris suddenly developed severe breathlessness with cyanosis and had fatal cardiac arrest and necropsy disclosed massive pulmonary embolism. The patient with subacute cor pulmonale had severe right-sided heart failure for 5 weeks and necropsy disclosed microscopic-sized neoplastic pulmonary emboli from a gastric carcinoma without parenchymal pulmonary metastases. The patient with chronic cor pulmonale had evidence of right-sided heart failure for years, the result of primary or idiopathic pulmonary hypertension almost certainly present from birth because the pattern of elastic fibers in the pulmonary trunk was that seen in newborns where the pressure in the pulmonary trunk and ascending aorta are similar. The patient with chronic cor pulmonale had plexiform pulmonary lesions indicative of irreversible pulmonary hypertension. Neither the acute nor the subacute patient had chronic pulmonary vascular changes. All 3 patients had dilated right ventricular cavities and non-dilated left ventricular cavities and only the patient with chronic cor pulmonale had right ventricular hypertrophy. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Comparison of four variants of a major allergen in hazelnut (Corylus avellana) Cor a 1.04 with the major hazel pollen allergen Cor a 1.01

    DEFF Research Database (Denmark)

    Lüttkopf, D; Müller, U; Skov, P S

    2002-01-01

    -blind placebo-controlled food challenges (DBPCFC) in a multicenter study. Total RNA was isolated from immature hazelnuts and transcribed into cDNA. Full length coding DNA obtained by PCR-strategy was subcloned into pTYB11 vector and expressed in E. coli ER2566 cells. Native non-fusion target proteins were...... purified by DTT-induced self-cleavage of the intein-tagged N-terminal fusion proteins. IgE reactivity of the recombinant allergens was tested by enzyme allergosorbent test (EAST), EAST-inhibition, immunoblot-inhibition and histamine release assays. Four recombinant allergens were produced showing deduced...... residue in position 99. Surprisingly, only 63% identity was revealed with hazel pollen Cor a 1. EAST with 43 sera of patients with positive DBPCFC to hazelnut indicated IgE reactivity to Cor a 1.0401 in 95% of the sera, to Cor a 1.0402 in 93%, to Cor a 1.0403 in 91%, and in only 74% of the sera...

  20. THE HEIGHT EVOLUTION OF THE ''TRUE'' CORONAL MASS EJECTION MASS DERIVED FROM STEREO COR1 AND COR2 OBSERVATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Bein, B. M.; Temmer, M.; Veronig, A. M.; Utz, D. [Kanzelhoehe Observatory-IGAM, Institute of Physics, University of Graz, Universitaetsplatz 5, A-8010 Graz (Austria); Vourlidas, A. [Space Science Division, Naval Research Laboratory, Washington, DC (United States)

    2013-05-01

    Using combined STEREO-A and STEREO-B EUVI, COR1, and COR2 data, we derive deprojected coronal mass ejection (CME) kinematics and CME ''true'' mass evolutions for a sample of 25 events that occurred during 2007 December to 2011 April. We develop a fitting function to describe the CME mass evolution with height. The function considers both the effect of the coronagraph occulter, at the beginning of the CME evolution, and an actual mass increase. The latter becomes important at about 10-15 R{sub Sun} and is assumed to mostly contribute up to 20 R{sub Sun }. The mass increase ranges from 2% to 6% per R{sub Sun} and is positively correlated to the total CME mass. Due to the combination of COR1 and COR2 mass measurements, we are able to estimate the ''true'' mass value for very low coronal heights (<3 R{sub Sun }). Based on the deprojected CME kinematics and initial ejected masses, we derive the kinetic energies and propelling forces acting on the CME in the low corona (<3 R{sub Sun }). The derived CME kinetic energies range between 1.0-66 Multiplication-Sign 10{sup 23} J, and the forces range between 2.2-510 Multiplication-Sign 10{sup 14} N.

  1. Digoxin therapy for cor pulmonale: A systematic review.

    Science.gov (United States)

    Alajaji, Wissam; Baydoun, Atallah; Al-Kindi, Sadeer G; Henry, Leslie; Hanna, Mazen A; Oliveira, Guilherme H

    2016-11-15

    Right heart failure is associated with increased mortality and morbidity. The optimal treatment for patients with RV failure is not established. The aim of this study is to conduct a systematic review of the literature to assess the relative benefits and harms of digoxin therapy in patients with RV failure. We performed a literature search in MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) on Nov. 4, 2014. We did not use publication type, period or language restrictions to the search strategy. Exclusions included: trials that excluded patients with RV failure, included patients requiring mechanical or intravenous inotropic support, review papers and case reports. The primary outcome was long-term efficacy outcomes of digoxin in right heart failure. Two reviewers screened titles and abstracts of identified citations independently and in duplication using calibration exercises and standardized screening forms. The search strategy identified 4097 citations, and 4 studies were included in this analysis (n=76 patients). Of the four studies, two assessed improvements in RVEF, two studies compared exercise capacity indexes, and one assessed symptoms with digoxin compared with placebo. No study assessed mortality outcomes. Overall, there was no statistically significant improvement in RVEF, exercise capacity, NYHA class, heart failure score, or body weight. There are few studies evaluating Digitalis use for RV failure, which are limited to patients with cor pulmonale. In these patients, Digitalis use provides no improvement in RVEF, exercise capacity, or NYHA class. Randomized clinical trials are needed to address this question. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease.

    Science.gov (United States)

    Ju, Chun-Rong; Chen, Miao; Zhang, Jian-Heng; Lin, Zhi-Ya; Chen, Rong-Chang

    2016-01-01

    To analyze plasma myostatin levels and investigate their relationship with right ventricular (RV) function in patients with cor pulmonale secondary to chronic obstructive pulmonary disease (COPD). The study recruited 81 patients with advanced COPD and 40 age-matched controls. The patients were divided into two groups: those with cor pulmonale and those without. Echocardiography was used to evaluate RV function and morphology, and the value of tricuspid annular plane systolic excursion (TAPSE) less than 16 mm was considered RV dysfunction. Plasma myostatin levels were analyzed by enzyme-linked immunosorbent assay, and B-type natriuretic peptide (BNP) levels were analyzed as a comparison of myostatin. The data detected cor pulmonale in 39/81 patients, with the mean value of TAPSE of 14.3 mm. Plasma myostatin levels (ng/mL) were significantly higher in patients with cor pulmonale (16.68 ± 2.95) than in those without (13.56 ± 3.09), and much higher than in controls (8.79±2.79), with each pcor pulmonale. Stronger correlations of plasma myostatin levels with echocardiographic indexes of the right heart suggest that myostatin might be superior to BNP in the early diagnosis of cor pulmonale in COPD.

  3. Tumores do plexo coróideo Choroid plexus tumors

    Directory of Open Access Journals (Sweden)

    GERALDO PIANETTI

    1998-06-01

    Full Text Available É feita análise estatística, semiológica, terapêutica e da evolução de 15 crianças portadoras de tumor do plexo coróideo, tratadas cirurgicamente no Serviço de Neuropediatria dos Hospitais das Clínicas (UFMG e São Francisco de Assis, num período de 15 anos (1981 a 1996. A idade variou de quatro meses a 16 anos, com média de três anos e seis meses, dez tinham menos de dois anos; nove eram do sexo feminino; 14 tinham sinais de hipertensão intracraniana; em todas elas a presença do tumor foi confirmada pelo estudo com tomografia computadorizada; em oito crianças o tumor estava localizado em um ventrículo lateral. Das 15 crianças, 11 necessitaram de derivação ventrículo-peritoneal; a exerese radical do tumor foi possível em 13 das 14 crianças operadas. O diagnóstico anátomo-patológico foi papiloma em 12 crianças e carcinoma nas outras duas. Duas crianças faleceram, uma no sétimo dia de pós-operatório e a outra 12 meses após, com metástases disseminadas pelo sistema nervoso central. É feita revisão da literatura pertinente e dados são comparados.This analysis comprises 15 children under 16 years of age, with choroid plexus tumors, seen in the Service of Paediatric Neurosurgery, Hospital das Clínicas and Hospital São Francisco de Assis in Belo Horizonte, Brazil, between 1981 and 1996. The patients were aged between 4 months and 16 years (average of 3 years and a half; 10 were less than 2 years, 9 were female; 14 children had clinical evidence of intracranial hypertension. All the children underwent CT scan and the choroid plexus tumors were clearly demonstrated in 14 of then. In 8 children the tumors were located in one lateral ventricle, 5 in the fourth ventricle and 2 had the tumors in more than one ventricle, 11 children required ventriculo-peritoneal shunt; 14 cases were operated on, 13 with total excision; 2 children died, respectively 7 days and one year after the surgery. Pathological examination revealed

  4. Identification and characterization of Cor33p, a novel protein implicated in tolerance towards oxidative stress in Candida albicans.

    Science.gov (United States)

    Sohn, K; Roehm, M; Urban, C; Saunders, N; Rothenstein, D; Lottspeich, F; Schröppel, K; Brunner, H; Rupp, S

    2005-12-01

    We applied two-dimensional gel electrophoresis to identify downstream effectors of CPH1 and EFG1 under hypha-inducing conditions in Candida albicans. Among the proteins that were expressed in wild-type cells but were strongly downregulated in a cph1Delta/efg1Delta double mutant in alpha-minimal essential medium at 37 degrees C, we could identify not-yet-characterized proteins, including Cor33-1p and Cor33-2p. The two proteins are almost identical (97% identity) and represent products of allelic isoforms of the same gene. Cor33p is highly similar to Cip1p from Candida sp. but lacks any significant homology to proteins from Saccharomyces cerevisiae. Strikingly, both proteins share homology with phenylcoumaran benzylic ether reductases and isoflavone reductases from plants. For other hypha-inducing media, like yeast-peptone-dextrose (YPD) plus serum at 37 degrees C, we could not detect any transcription for COR33 in wild-type cells, indicating that Cor33p is not hypha specific. In contrast, we found a strong induction for COR33 when cells were treated with 5 mM hydrogen peroxide. However, under oxidative conditions, transcription of COR33 was not dependent on EFG1, indicating that other regulatory factors are involved. In fact, upregulation depends on CAP1 at least, as transcript levels were clearly reduced in a Deltacap1 mutant strain under oxidative conditions. Unlike in wild-type cells, transcription of COR33 in a tsa1Delta mutant can be induced by treatment with 0.1 mM hydrogen peroxide. This suggests a functional link between COR33 and thiol-specific antioxidant-like proteins that are important in the oxidative-stress response in yeasts. Concordantly, cor33Delta deletion mutants show retarded growth on YPD plates supplemented with hydrogen peroxide, indicating that COR33 in general is implicated in conferring tolerance toward oxidative stress on Candida albicans.

  5. Not all resources are created equal: COR theory, values, and stress.

    Science.gov (United States)

    Morelli, Neil A; Cunningham, Christopher J L

    2012-01-01

    The common usage of conservation of resources (COR) theory highlights the quantity of resources in explaining stress reactions and responses. To expand the theoretical understanding and explanatory power of COR theory, this study tested the proposition that the perceived importance of an individual's resources is a function of personal values. Using a value framework based on Schwartz (1994), it was expected that values would influence both the appraisal of resource importance and coping behaviors. Results from both student and working samples indicated that while resource importance did not clearly mediate all of the coping outcomes, values did have an influence on the importance an individual assigns to resources. Measurement and theoretical implications related to COR theory are discussed.

  6. [Diagnosis of predisposition to chronic cor pulmonale formation in occupational lung diseases caused by dust].

    Science.gov (United States)

    Panev, N I; Korotenko, O Iu; Zakharenkov, V V; Korchagina, Iu S; Gafarov, N I

    2014-01-01

    Study covered 426 miners aged 40-54 years with previously diagnosed occupational respiratory diseases due to dust (246 patients with chronic occupational obstructive bronchitis, 98 with anthracosilicosis and 82 with chronic dust nonobstructive bronchitis). 315 (73.9%) examinees out of 426 with lung diseases due to dust demonstrated chronic cor pulnmonale. Considering high share of this complication, the authors used Bayes method to create a method to diagnose predisposition towards chronic cor pulmonale in patients with dust lung diseases through respiratory failure, concomitant coronary heart disease and arterial hypertension, blood groups ABO, MN and P, some structural and functional parameters of heart: myocardium weight index, relative wall thickness index and left ventricle sphericity index, average lung artery pressure. Increasing number of analyzed factors that directly influence chronic cor pulmonale development and selecting additional markers help to improve forecasting of the complication.

  7. Purification and crystallization of Cor a 9, a major hazelnut allergen

    International Nuclear Information System (INIS)

    Guo, Feng; Kothary, Mahendra H.; Wang, Yang; Yu, Xiaoping; Howard, Andrew J.; Fu, Tong-Jen; Zhang, Yu-Zhu

    2008-01-01

    The major hazelnut allergen Cor a 9 was purified from the natural source and crystallized. Diffraction data were collected to 1.9 Å resolution using a synchrotron-radiation source. Hazelnut (Corylus avellana) is one of the food sources that induce allergic reaction in a subpopulation of people with food allergy. The 11S legumin-like seed-storage protein from hazelnut has been identified as one of the major hazelnut allergens and named Cor a 9. In this study, Cor a 9 was extracted from hazelnut kernels using a high-salt solution and was purified by desalting out and FPLC to a highly purified state. Diffraction-quality single crystals were obtained using the hanging-drop vapour-diffusion method. Diffraction data were collected and a structure solution has been obtained by molecular-replacement calculations. Further refinement of the structure is currently in progress

  8. NASA Astrophysics Cosmic Origins (COR) and Physics of the Cosmos (PCOS) Strategic Technology Development Program

    Science.gov (United States)

    Pham, Thai; Seery, Bernard D.

    2015-01-01

    The COR and PCOS Program Offices (PO) reside at the NASA Goddard Space Flight Center (GSFC), serving as the NASA Astrophysics Division's implementation arm for matters relating to the two programs. One aspect of the PO's activities is managing the COR and PCOS Strategic Astrophysics Technology (SAT) program, helping mature technologies to enable and enhance future astrophysics missions.The PO is guided by the National Research Council's 'New Worlds, New Horizons in Astronomy and Astrophysics' Decadal Survey report, and NASA's Astrophysics Implementation Plan. Strategic goals include dark energy; gravitational waves; X-ray observatories, e.g., US participation in ATHENA; Inflation probe; and a large UV/Visible telescope.To date, 51 COR and 65 PCOS SAT proposals have been received, of which 11 COR and 18 PCOS projects were funded. Notable successes include maturation of a new far-IR detector, later adopted by the SOFIA HAWC instrument; maturation of the H4RG near-IR detector, adopted by WFIRST; development of an antenna-coupled transition-edge superconducting bolometer, a technology deployed by BICEP2 that allowed measurement of B-mode polarization in the CMB signal, a possible signature of Inflation; and finally, the REXIS instrument on OSIRIS-REx is incorporating CCDs with directly deposited optical blocking filters developed by another SAT-funded project.We discuss our technology development process, with community input and strategic prioritization informing calls for SAT proposals and guiding investment decisions. We also present results of this year's technology gap prioritization and showcase our current portfolio of technology development projects. These include five newly selected projects, kicking off in FY 2015.For more information, visit the COR Program website at cor.gsfc.nasa.gov and the PCOS website at pcos.gsfc.nasa.gov.

  9. Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease.

    Directory of Open Access Journals (Sweden)

    Chun-Rong Ju

    Full Text Available To analyze plasma myostatin levels and investigate their relationship with right ventricular (RV function in patients with cor pulmonale secondary to chronic obstructive pulmonary disease (COPD.The study recruited 81 patients with advanced COPD and 40 age-matched controls. The patients were divided into two groups: those with cor pulmonale and those without. Echocardiography was used to evaluate RV function and morphology, and the value of tricuspid annular plane systolic excursion (TAPSE less than 16 mm was considered RV dysfunction. Plasma myostatin levels were analyzed by enzyme-linked immunosorbent assay, and B-type natriuretic peptide (BNP levels were analyzed as a comparison of myostatin.The data detected cor pulmonale in 39/81 patients, with the mean value of TAPSE of 14.3 mm. Plasma myostatin levels (ng/mL were significantly higher in patients with cor pulmonale (16.68 ± 2.95 than in those without (13.56 ± 3.09, and much higher than in controls (8.79±2.79, with each p<0.01. Significant differences were also found in plasma BNP levels among the three groups (p<0.05. Multivariate regression analysis suggested that myostatin levels were significantly correlated with the values of TAPSE and RV myocardium performance index among the COPD patients, and that BNP levels were significantly correlated only with systolic pulmonary arterial pressure, with each p<0.05.Plasma myostatin levels are increased in COPD patients who have cor pulmonale. Stronger correlations of plasma myostatin levels with echocardiographic indexes of the right heart suggest that myostatin might be superior to BNP in the early diagnosis of cor pulmonale in COPD.

  10. Carcinoma bilateral do plexo coróide operado com sucesso

    Directory of Open Access Journals (Sweden)

    Gilberto M. de Almeida

    1970-06-01

    Full Text Available Os autores não encontraram na literatura caso de carcinoma bilateral do plexo coróide operado com sucesso. O trabalho consta da apresentação de uma criança de 11 anos com carcinoma dos plexos coróides nos dois ventrículos laterais. São feitas considerações a respeito das dificuldades no diagnóstico, da importância dó estudo angiográfico completo e do tratamento

  11. Combining STEREO SECCHI COR2 and HI1 images for automatic CME front edge tracking

    Directory of Open Access Journals (Sweden)

    Kirnosov Vladimir

    2016-01-01

    Full Text Available COR2 coronagraph images are the most commonly used data for coronal mass ejection (CME analysis among the various types of data provided by the STEREO (Solar Terrestrial Relations Observatory SECCHI (Sun-Earth Connection Coronal and Heliospheric Investigation suite of instruments. The field of view (FOV in COR2 images covers 2–15 solar radii (Rs that allow for tracking the front edge of a CME in its initial stage to forecast the lead-time of a CME and its chances of reaching the Earth. However, estimating the lead-time of a CME using COR2 images gives a larger lead-time, which may be associated with greater uncertainty. To reduce this uncertainty, CME front edge tracking should be continued beyond the FOV of COR2 images. Therefore, heliospheric imager (HI1 data that covers 15–90 Rs FOV must be included. In this paper, we propose a novel automatic method that takes both COR2 and HI1 images into account and combine the results to track the front edges of a CME continuously. The method consists of two modules: pre-processing and tracking. The pre-processing module produces a set of segmented images, which contain the signature of a CME, for both COR2 and HI1 separately. In addition, the HI1 images are resized and padded, so that the center of the Sun is the central coordinate of the resized HI1 images. The resulting COR2 and HI1 image set is then fed into the tracking module to estimate the position angle (PA and track the front edge of a CME. The detected front edge is then used to produce a height-time profile that is used to estimate the speed of a CME. The method was validated using 15 CME events observed in the period from January 1, 2008 to August 31, 2009. The results demonstrate that the proposed method is effective for CME front edge tracking in both COR2 and HI1 images. Using this method, the CME front edge can now be tracked automatically and continuously in a much larger range, i.e., from 2 to 90 Rs, for the first time. These

  12. Avaliação da cor de peras secadas por diferentes métodos.

    OpenAIRE

    Carrilha, Fátima; Guiné, Raquel

    2010-01-01

    A pêra secada é um fruto com características únicas, sendo a sua cor um parâmetro físico que o consumidor avalia após o primeiro contacto com o alimento. Neste contexto torna-se importante adquirir conhecimentos acerca da cor das peras, a qual que confere ao produto secado uma maior ou menor aceitação. Neste trabalho as variedades de peras a serem estudadas são as peras da variedade portuguesa denominada por S. Bartolomeu, que depois de secada origina a pêra passa de Viseu. Estas peras são...

  13. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    OpenAIRE

    Gabriela Soncini Pasetto; Henrique Pedroso de Freitas; Carina Graziottin Colossi; Manuel Augusto Pereira Vilela

    2013-01-01

    OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9%) foram incluídos no estudo. ...

  14. Acute Cor Pulmonale in Veno-Venous Extracorporeal Membrane Oxygenation: Three Case Reports.

    Science.gov (United States)

    Dong, Erik R; Ng, David G; Ramzy, Danny; Chung, Joshua S; Friedman, Oren; Combes, Alain; Arabia, Francisco A; Nurok, Michael

    2018-01-10

    A retrospective review of three patients with acute respiratory distress syndrome (ARDS) and normal baseline right ventricular function admitted to the Cardiac Surgery Intensive Care Unit whom developed acute cor pulmonale while on veno-venous extracorporeal membrane oxygenation. These patients were diagnosed with ARDS using Berlin Criteria definitions and cannulated with a dual lumen (Avalon) cannula. Despite variations in history, presentation, and course, findings of acute cor pulmonale were encountered 4 to 6 weeks after extracorporeal membrane oxygenation cannulation. The potential mechanisms include thromboembolic burden to the pulmonary vasculature, hypoxemia, acidosis, the pathologic progression of ARDS, and chronic nonphysiologic flow to the right heart.

  15. Cor pulmonale and silicosis: a necropsy based case-control study.

    Science.gov (United States)

    Murray, J; Reid, G; Kielkowski, D; de Beer, M

    1993-01-01

    The presence of cor pulmonale at death in relation to other factors such as emphysema, silicosis, and thromboembolism was analysed in a case-control study of 732 South African gold miners. Marked emphysema was the highest risk factor with an odds ratio of 21.32 (95% confidence interval (95% CI) 5.02-90.7), then extensive silicosis (OR 4.95, 95% CI 2.92-8.38) and thromboembolic disease (OR 1.92, 95% CI 1.37-2.69). Age and smoking were not significant predictors of cor pulmonale. PMID:8329320

  16. Paroxysmal atrial fibrillation and clinically reversible cor pulmonale in a horse with complicated recurrent airway obstruction.

    Science.gov (United States)

    Hanka, J; van den Hoven, R; Schwarz, B

    2015-01-01

    Cor pulmonale is considered an uncommon complication in horses with recurrent airway obstruction (RAO). This case report describes the history, clinical and further examination findings, treatment, progression and outcome of a horse diagnosed with cor pulmonale and paroxysmal atrial fibrillation of 2 days duration due to a severe exacerbation of RAO. To our best knowledge, this is the first report of RAO induced pulmonary hypertension in a horse causing atrial fibrillation. However, even severe cardiac changes due to respiratory dysfunction seem to be largely reversible in horses.

  17. Cor a 14 is the superior serological marker for hazelnut allergy in children, independent of concomitant peanut allergy

    DEFF Research Database (Denmark)

    Eller, Esben; Mortz, Charlotte G; Bindslev-Jensen, Carsten

    2016-01-01

    BACKGROUND: Hazelnut is the most frequent cause of tree-nut allergy, but up to half of all children with hazelnut allergy additionally suffers from peanut allergy. Our aim was to identify diagnostic values of the most promising serological markers (Cor a 9 and Cor a 14) and to address the influen...

  18. Alterations of CorTFL1 and CorAP1 expression correlate with major evolutionary shifts of inflorescence architecture in Cornus (Cornaceae) - a proposed model for variation of closed inflorescence forms.

    Science.gov (United States)

    Ma, Qing; Liu, Xiang; Franks, Robert G; Xiang, Qiu-Yun Jenny

    2017-10-01

    TFL1-, AP1- and LFY-like genes are known to be key regulators of inflorescence development. However, it remains to be tested whether the evolutionary modifications of inflorescence morphology result from shifts in their expression patterns. We compared the spatiotemporal expression patterns of CorTFL1, CorAP1 and CorLFY in six closely related Cornus species that display four types of closed inflorescence morphology using quantitative real-time polymerase chain reaction (qRT-PCR) and RNA in situ hybridization. Character mapping on the phylogeny was conducted to identify evolutionary changes and to assess the correlation between changes in gene expression and inflorescence morphology. Results demonstrated variation of gene expression patterns among species and a strong correlation between CorTFL1 expression and the branch index of the inflorescence type. Evolutionary changes in CorTFL1 and CorAP1 expression co-occurred on the phylogeny with the morphological changes underpinning inflorescence divergence. The study found a clear correlation between the expression patterns of CorTFL1 and CorAP1 and the inflorescence architecture in a natural system displaying closed inflorescences. The results suggest a role for the alteration in CorTFL1 and CorAP1 expression during the evolutionary modification of inflorescences in Cornus. We propose that a TFL1-like and AP1-like gene-based model may explain variation of closed inflorescences in Cornus and other lineages. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  19. Impact of Maillard Reaction on Immunoreactivity and Allergenicity of the Hazelnut Allergen Cor a 11

    NARCIS (Netherlands)

    Iwan, M.; Vissers, Y.M.; Fiedorowicz, E.; Kostyra, H.; Savelkoul, H.F.J.; Wichers, H.J.

    2011-01-01

    Few studies exist on the influence of processing methods on structural changes and allergenic potential of hazelnut proteins. This study focused on the effect of glycation (Maillard reaction) on the immunoreactivity and degranulation capacity of the purified hazelnut 7S globulin, Cor a 11. After

  20. Coeficiente de erodibilidade em sulcos e entressulcosde Argissolos coesos estimado pela cor do solo

    Directory of Open Access Journals (Sweden)

    Jussara Silva Dantas

    2014-09-01

    Full Text Available O objetivo deste trabalho foi estimar o coeficiente de erodibilidade em sulcos e entressulcos, por meio de parâmetros da cor do solo. Foram selecionadas três áreas cultivadas com soja, em Argissolos Amarelos coesos do Leste Maranhense. Em cada área, foram retiradas 121 amostras na profundidade de 0,00-0,20 m. Foram determinados os valores de espectroscopia de reflectância difusa na faixa do visível, para obtenção dos valores de matiz, valor e croma. A partir destes constituintes da cor, foi calculado o índice de avermelhamento para cada amostra. Foram desenvolvidos modelos para avaliar o efeito de cada componente da cor sobre a erodibilidade em sulcos e entressulcos. Esses componentes apresentaram R2 que variou de 0,37 a 0,70. Os modelos gerados obtiveram R2 de 0,70 e 0,73, para entressulcos e sulcos, respectivamente. A cor do solo determinada por espectroscopia de reflectância difusa pode ser utilizada como método alternativo para estimar o coeficiente de erodibilidade de Argissolos Amarelos coesos.

  1. Primair sarcoom van de A. pulmonalis : zeldzame oorzaak van cor pulmonale

    NARCIS (Netherlands)

    Ismaël, F; van der Werf, T S; de Boer, W J; Timens, W; Nossent, G D; Ligtenberg, J J

    1999-01-01

    A 64-year-old female presented with fever and weight loss, accompanied by normochromic normocytic anaemia with high erythrocyte sedimentation rate. She developed severe cor pulmonale. Ventilation-perfusion scintigraphy revealed a non-matched perfusion defect of the entire right lung with impaired

  2. Hypoxic hepatitis during the perioperative period in patients with severe pulmonary disease and cor pulmonale.

    Science.gov (United States)

    Kim, Hyuckgoo; Park, Sang-Jin; Lee, Deokhee

    2017-01-01

    Hypoxic hepatitis (HH) is characterized by marked and transient elevations in liver enzyme levels in the absence of other potential causes of liver injury. Although rare, it can occur in the presence of hemodynamic instability and hypoxemia in patients with cor pulmonale. We report two cases of perioperative HH in patients with severe pulmonary disease and cor pulmonale. The first case is of a patient with cor pulmonale who underwent hemiarthroplasty for a femur fracture. Transient hypotension developed during spinal anesthesia and severe hypoxemia were observed in the postoperative period. After surgery, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels suddenly increased to 3740 and 817 U/L, respectively. The second case is of a patient with congestive heart failure and cor pulmonale whose blood pressure and oxygen saturation decreased during induction of general anesthesia and after surgery, and AST, ALT, and lactic dehydrogenase levels increased to 1291, 1292, and 2710 U/L, respectively. The liver enzyme levels normalized within 7-14 days in both cases. We speculate the diagnosis of these cases as HH.

  3. The meaning of Harpax in 1 Cor 5:10: An exegetical study | Berchie ...

    African Journals Online (AJOL)

    Different renderings of Paul's use of harpax in 1 Cor 5:10 by biblical interpreters have suggested different meanings. Through lexico-semantic analysis, this paper contends that this word should be understood as an act of taking forcibly what is not one's own. Harpax and pleonektes are syntactically and semantically related.

  4. Staphylococcal toxic shock syndrome presenting as acute respiratory distress and cor pulmonale.

    Science.gov (United States)

    Zaki, S A; Shanbag, P; Chavan, V; Shenoy, P

    2010-01-01

    We describe a 7-year-old boy with staphylococcal toxic shock syndrome who presented with acute respiratory distress and cor pulmonale. We wish to highlight this unusual presentation as the diagnosis of toxic shock syndrome depends chiefly on a high degree of clinical suspicion. Early diagnosis and prompt institution of appropriate therapy will significantly reduce morbidity and mortality.

  5. C-type natriuretic peptide levels in cor pulmonale and in congestive heart failure.

    Science.gov (United States)

    Cargill, R. I.; Barr, C. S.; Coutie, W. J.; Struthers, A. D.; Lipworth, B. J.

    1994-01-01

    BACKGROUND--C-type natriuretic peptide (CNP) is a recent addition to the family of natriuretic peptides which includes atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Whilst the levels of ANP and BNP are increased in conditions such as congestive heart failure and cor pulmonale, abnormal levels of CNP in these conditions have not been reported. METHODS--Plasma levels of CNP were measured by specific radioimmunoassay in 12 young normal controls, 12 elderly normal controls, 12 patients with NYHA grade III-IV congestive heart failure, and in 16 patients with hypoxaemic cor pulmonale. RESULTS--Mean (SE) plasma levels of CNP were similar in young normal controls (0.46(0.03) pmol/l), elderly normal controls (0.43(0.05) pmol/l), and in patients with congestive heart failure (0.33(0.2) pmol/l). In patients with cor pulmonale, however, plasma levels of CNP were raised (1.39(0.27) pmol/l) 3.2-fold compared with age-matched controls. CONCLUSIONS--In cor pulmonale the increased plasma levels of CNP were not as great as the previously observed increases in levels of ANP (5.6-fold) or BNP (18.5-fold) in comparable patients. CNP may therefore be less important than ANP or BNP as a circulating counter-regulatory peptide in conditions of overactivity of the renin angiotensin system. PMID:7878562

  6. Hypoxic hepatitis during the perioperative period in patients with severe pulmonary disease and cor pulmonale

    Directory of Open Access Journals (Sweden)

    Hyuckgoo Kim

    2017-01-01

    Full Text Available Hypoxic hepatitis (HH is characterized by marked and transient elevations in liver enzyme levels in the absence of other potential causes of liver injury. Although rare, it can occur in the presence of hemodynamic instability and hypoxemia in patients with cor pulmonale. We report two cases of perioperative HH in patients with severe pulmonary disease and cor pulmonale. The first case is of a patient with cor pulmonale who underwent hemiarthroplasty for a femur fracture. Transient hypotension developed during spinal anesthesia and severe hypoxemia were observed in the postoperative period. After surgery, aspartate aminotransferase (AST and alanine aminotransferase (ALT levels suddenly increased to 3740 and 817 U/L, respectively. The second case is of a patient with congestive heart failure and cor pulmonale whose blood pressure and oxygen saturation decreased during induction of general anesthesia and after surgery, and AST, ALT, and lactic dehydrogenase levels increased to 1291, 1292, and 2710 U/L, respectively. The liver enzyme levels normalized within 7–14 days in both cases. We speculate the diagnosis of these cases as HH.

  7. Pulmonary tumor thrombotic microangiopathy with cor pulmonale due to desmoplastic small round cell tumor.

    Science.gov (United States)

    Sadimin, Evita T; Collier, Adrienne G; Gaffney, Joseph W; Fyfe, Billie

    2012-04-01

    A 12-year-old boy presented acutely after an episode of syncope with perioral cyanosis. He died 19 hours after admission due to cor pulmonale as a complication of metastatic desmoplastic small round cell tumor in the lungs with associated tumor thrombotic microangiopathy. Copyright © 2012 Mosby, Inc. All rights reserved.

  8. A rare case of cor pulmonale secondary to idiopathic pulmonary fibrosis in Nigeria.

    Science.gov (United States)

    Anakwue, Raphael Chinedu; Chijioke, Chioli Paschal; Iloanusi, Nneka Ifeyinwa

    2011-06-29

    Idiopathic pulmonary fibrosis (IPF) is a rarely reported disease in Nigeria. Cor pulmonale, one of the complications of this type of diffuse parenchymal lung disease is even rarer. The authors present a Nigerian patient with IPF with a classical high-resolution CT features, managed in our centre together with associated problems.

  9. Advanced sickle cell associated interstitial lung disease presenting with cor pulmonale in a Nigerian.

    Science.gov (United States)

    Fawibe, Ademola Emmanuel; Kolo, Philip Manman; Ogunmodede, James Ayodele; Desalu, Olufemi Olumuyiwa; Salami, Kazeem Alakija

    2012-04-01

    Previous studies have reported abnormal pulmonary function and pulmonary hypertension among Nigerians with sickle cell disease, but there is no report of interstitial lung disease among them. We report a Nigerian sickle cell patient who presented with computed tomography proven interstitial lung disease complicated by pulmonary hypertension and cor pulmonale.

  10. The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana.

    Science.gov (United States)

    Shi, Yihao; Huang, Jiaying; Sun, Tianshu; Wang, Xuefei; Zhu, Chenqi; Ai, Yuxi; Gu, Hongya

    2017-02-01

    The transcription factors CBF1/2/3 are reported to play a dominant role in the cold responsive network of Arabidopsis by directly regulating the expression levels of cold responsive (COR) genes. In this study, we obtained CRISPR/Cas9-mediated loss-of-function mutants of cbf1∼3. Over 3,000 COR genes identified by RNA-seq analysis showed a slight but significant change in their expression levels in the mutants compared to the wild-type plants after being treated at 4 °C for 12 h. The C-repeat (CRT) motif (5'-CCGAC-3') was enriched in promoters of genes that were up-regulated by CBF2 and CBF3 but not in promoters of genes up-regulated by CBF1. These data suggest that CBF2 and CBF3 play a more important role in directing the cold response by regulating different sets of downstream COR genes. More than 2/3 of COR genes were co-regulated by two or three CBFs and were involved mainly in cellular signal transduction and metabolic processes; less than 1/3 of the genes were regulated by one CBF, and those genes up-regulated were enriched in cold-related abiotic stress responses. Our results indicate that CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network. © 2016 The Authors. Journal of Integrative Plant Biology Published by John Wiley & Sons Australia, Ltd on behalf of Institute of Botany, Chinese Academy of Sciences.

  11. Automatic near-real-time detection of CMEs in Mauna Loa K-Cor coronagraph images

    Science.gov (United States)

    Thompson, W. T.; St Cyr, O. C.; Burkepile, J.; Posner, A.

    2017-12-01

    A simple algorithm has been developed to detect the onset of coronal massejections (CMEs), together with an estimate of their speed, in near-real-timeusing images of the linearly polarized white-light solar corona taken by theK-Cor telescope at the Mauna Loa Solar Observatory (MLSO). The algorithm usedis a variation on the Solar Eruptive Event Detection System (SEEDS) developedat George Mason University. The algorithm was tested against K-Cor data takenbetween 29 April 2014 and 20 February 2017, on days which the MLSO websitemarked as containing CMEs. This resulted in testing of 139 days worth of datacontaining 171 CMEs. The detection rate varied from close to 80% in 2014-2015when solar activity was high, down to as low as 20-30% in 2017 when activitywas low. The difference in effectiveness with solar cycle is attributed to thedifference in relative prevalance of strong CMEs between active and quietperiods. There were also twelve false detections during this time period,leading to an average false detection rate of 8.6% on any given day. However,half of the false detections were clustered into two short periods of a fewdays each when special conditions prevailed to increase the false detectionrate. The K-Cor data were also compared with major Solar Energetic Particle(SEP) storms during this time period. There were three SEP events detectedeither at Earth or at one of the two STEREO spacecraft where K-Cor wasobserving during the relevant time period. The K-Cor CME detection algorithmsuccessfully generated alerts for two of these events, with lead times of 1-3hours before the SEP onset at 1 AU. The third event was not detected by theautomatic algorithm because of the unusually broad width of the CME in positionangle.

  12. cor, a novel carbon monoxide resistance gene, is essential for Mycobacterium tuberculosis pathogenesis.

    Science.gov (United States)

    Zacharia, Vineetha M; Manzanillo, Paolo S; Nair, Vidhya R; Marciano, Denise K; Kinch, Lisa N; Grishin, Nick V; Cox, Jeffery S; Shiloh, Michael U

    2013-11-19

    Tuberculosis, caused by Mycobacterium tuberculosis, remains a devastating human infectious disease, causing two million deaths annually. We previously demonstrated that M. tuberculosis induces an enzyme, heme oxygenase (HO1), that produces carbon monoxide (CO) gas and that M. tuberculosis adapts its transcriptome during CO exposure. We now demonstrate that M. tuberculosis carries a novel resistance gene to combat CO toxicity. We screened an M. tuberculosis transposon library for CO-susceptible mutants and found that disruption of Rv1829 (carbon monoxide resistance, Cor) leads to marked CO sensitivity. Heterologous expression of Cor in Escherichia coli rescued it from CO toxicity. Importantly, the virulence of the cor mutant is attenuated in a mouse model of tuberculosis. Thus, Cor is necessary and sufficient to protect bacteria from host-derived CO. Taken together, this represents the first report of a role for HO1-derived CO in controlling infection of an intracellular pathogen and the first identification of a CO resistance gene in a pathogenic organism. Macrophages produce a variety of antimicrobial molecules, including nitric oxide (NO), hydrogen peroxide (H2O2), and acid (H+), that serve to kill engulfed bacteria. In addition to these molecules, human and mouse macrophages also produce carbon monoxide (CO) gas by the heme oxygenase (HO1) enzyme. We observed that, in contrast to other bacteria, mycobacteria are resistant to CO, suggesting that this might be an evolutionary adaptation of mycobacteria for survival within macrophages. We screened a panel of ~2,500 M. tuberculosis mutants to determine which genes are required for survival of M. tuberculosis in the presence of CO. Within this panel, we identified one such gene, cor, that specifically confers CO resistance. Importantly, we found that the ability of M. tuberculosis cells carrying a mutated copy of this gene to cause tuberculosis in a mouse disease model is significantly attenuated. This indicates that

  13. Interfaces et reconfigurations de la question Nord/Sud en Corée.

    Directory of Open Access Journals (Sweden)

    Valérie Gelézeau

    2010-12-01

    Full Text Available S’appuyant sur un travail pluridisciplinaire autour de la notion d’interface, l’article propose de nouvelles perspectives d’analyse de la question Nord/Sud en Corée en considérant la partition entre Corée du Nord et Corée du Sud non plus comme un simple contexte géopolitique mais comme une matrice structurante des deux sociétés. Trois grands types d’interfaces entre les deux Corées sont identifiés et analysés à travers plusieurs études de cas : les interfaces spatiales (la frontière inter-coréenne, la frontière sino-nord-coréenne, ou encore les enclaves économiques développées au Nord par la Corée du Sud, les interfaces sociales (la communauté des Nord-Coréens au Sud, les élites sud-coréennes originaires du Nord, ou les échanges culturels nés de l’introduction au Sud de la peinture nord-coréenne, les interfaces narratives renvoyant aux discours que chaque Corée construit sur l’Autre, que ce soient les discours officiels (manuels scolaires, agences de presse ou ceux de la fiction (cinéma. Prolongeant le travail des géographes sur la notion, l’article s’efforce de mieux décrire la géométrie du système que constitue une interface (multiplicité des plans et des niveaux de contacts, jeu des synapses et des interstices, prégnance des enclaves non seulement sur le plan spatial mais aussi sur les plans social et narratif et de reconsidérer l’extraordinaire complexité de la culture coréenne contemporaine. Malgré les divergences de vues sur l’existence même d’une interface entre les deux Corées, l’article conclut que l’usage de ce concept a contribué à mettre en évidence la prégnance de cette division au cœur des deux Corées, à tous les niveaux de la sphère sociale et jusque dans le discours des études coréennes. En exposant les frontières divisant les discours et les savoirs sur la péninsule selon un paradigme bipolaire, le concept d’interface a pu permettre de

  14. Cor a 14, the allergenic 2S albumin from hazelnut, is highly thermostable and resistant to gastrointestinal digestion.

    Science.gov (United States)

    Pfeifer, Sabine; Bublin, Merima; Dubiela, Pawel; Hummel, Karin; Wortmann, Judith; Hofer, Gerhard; Keller, Walter; Radauer, Christian; Hoffmann-Sommergruber, Karin

    2015-10-01

    Allergens from nuts frequently induce severe allergic reactions in sensitive individuals. The aim of this study was to elucidate the physicochemical characteristics of natural Cor a 14, the 2S albumin from hazelnut. Cor a 14 was purified from raw hazelnuts using a combination of precipitation and chromatographic techniques. The protein was analyzed using gel electrophoresis, MS, and far-UV circular dichroism (CD) analyses. The immunoglobulin E (IgE) binding of native, heat-treated, and in vitro digested Cor a 14 was studied. We identified two different Cor a 14 isoforms and showed microclipping at the C-terminus. CD spectra at room temperature showed the typical characteristics of 2S albumins, and temperatures of more than 80°C were required to start unfolding of Cor a 14 demonstrating its high stability to heat treatment. In vitro digestion experiments revealed that Cor a 14 is resistant to proteolytic degradation. Native and heat-treated protein was recognized by sera from hazelnut allergic patients. However, denaturation of the allergen led to significantly reduced IgE binding. We identified two different isoforms of Cor a 14 displaying high stability under heating and gastric and duodenal conditions. Data from IgE-binding experiments revealed the existence of both, linear and conformational epitopes. © 2015 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Assessment of the right and left ventricular function in patients with cor pulmonale using high-definition CT.

    Science.gov (United States)

    Gao, Yan; Qin, Jian; DU, Xiang-ying; Yang, Jing; Li, Kun-cheng

    2013-01-01

    Cor pulmonale is often associated with changes of structure and function of the right ventricle (RV) and thus further affects functional changes of the left heart. Our study aimed to assess the left ventricular (LV) and RV function in patients with cor pulmonale using high-definition CT (HDCT). We prospectively studied 18 cor pulmonale patients determined by the pulmonary function test, clinical examination, chest radiograph, electrocardiogram, and echocardiogram. The subject group was compared to a control group consisting of 18 subjects. The RV and LV functions and RV myocardial mass (MM) were obtained by HDCT in the two groups. The results were compared between the two groups using the independent sample t test. Echocardiographic examination for cardiac function analysis was performed on the same day. The RV end-diastolic volume (EDV), RV end-systolic volume (ESV) and RV myocardial mass were significantly larger in the 18 cor pulmonale patients than in the control group (P cor pulmonale patients than in controls (P cor pulmonale patients than in controls (P cor pulmonale, while at the same time the left ventricular function is also impaired.

  16. Cor a 14 is the superior serological marker for hazelnut allergy in children, independent of concomitant peanut allergy.

    Science.gov (United States)

    Eller, E; Mortz, C G; Bindslev-Jensen, C

    2016-04-01

    Hazelnut is the most frequent cause of tree nut allergy, but up to half of all children with hazelnut allergy additionally suffer from peanut allergy. Our aim was to identify diagnostic values of the most promising serological markers (Cor a 9 and Cor a 14) and to address the influence of concomitant peanut allergy and PR10 sensitization. We included 155 children suspected of hazelnut allergy and challenged according to the guidelines. Concomitant allergy to peanuts was verified or ruled out by challenge. Skin prick test, s-IgE and CRD to hazelnut, peanut, PR10 and LPT protein families were measured using ImmunoCAP. Sixty-five children had a positive hazelnut challenge, and 60% of these also had a concomitant peanut allergy. Children allergic to hazelnut were sensitized to Cor a 9 and Cor a 14; peanut-allergic children were sensitized to Ara h 2. Sensitization to PR10 protein components was seen in 45% of all included children, irrelevant to allergy to peanut or hazelnut. A cut-off >0.72 kU/L of IgE towards Cor a 14 diagnosed 87% correctly, making Cor a 14 the superior serology marker. However, nine hazelnut-allergic children were primarily sensitized to Cor a 9. Concomitant peanut allergy is common in hazelnut-allergic children, but decision points as well as diagnostic values for Cor a 14 are not affected. We found three independent and well-characterized serotypes; hazelnut-allergic children were sensitized to Cor a 14, peanut-allergic children were sensitized to Ara h 2, and independently of this were children sensitized to birch pollen (Bet v 1). © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. An autopsy case of subacute cor pulmonale due to pulmonary tumor cell emboli in a patient with gastric cancer.

    Science.gov (United States)

    Iwakami, Shin-ichiro; Sato, Teruhiko; Takagi, Haruhi; Fujii, Mitsuhiro; Iwakami, Naoko; Yoshimi, Kaku; Koyama, Ryo; Ichikawa, Masako; Yoshioka, Masakata; Takahashi, Kazuhisa

    2009-01-01

    A 53-year-old woman was admitted to our hospital due to a severe respiratory condition and malnutrition. Radiological and electrophysiological findings suggested the existence of inexplicable cor pulmonale. Although we commenced to determine the causes of her severe condition, she suddenly died 3 days after admission. Postmortem autopsy revealed tumor cell microemboli in the small pulmonary arteries due to gastric cancer. Such a case of cor pulmonale as the first clinical manifestation is exceptionally rare. Occult malignancy should be considered as a differential diagnosis when one encounters a patient with subacutely aggravated respiratory condition and inexplicable cor pulmonale.

  18. Changes in atrial natriuretic peptide concentrations during intravenous saline infusion in hypoxic cor pulmonale.

    Science.gov (United States)

    Stewart, A G; Bardsley, P A; Baudouin, S V; Waterhouse, J C; Thompson, J S; Morice, A H; Howard, P

    1991-01-01

    BACKGROUND: The pathogenesis of oedema in hypoxic cor pulmonale is poorly understood. One possibility is a failure of atrial natriuretic peptide release, leading to salt and water retention. This hypothesis was tested by observing the response to an intravenous saline challenge in patients with and without cor pulmonale. METHODS: Plasma atrial natriuretic peptide concentrations were measured before and for three hours after an intravenous saline load (0.1 ml 2.7% saline/kg/min for 60 minutes) in 20 patients with chronic obstructive airways disease. Ten patients with cor pulmonale, as judged clinically by the presence of peripheral oedema with a previously documented increase in the jugular venous pressure or pleural effusions during an acute exacerbation of airway obstruction (mean (SE) age 67 (3) years, FEV1 0.73 (0.08) 1, arterial oxygen tension (PaO2) 6.4 (0.4) kPa, and arterial carbon dioxide tension (PaCO2) 6.7 (0.3) kPa), were compared with 10 patients with hypoxic chronic obstructive airways disease who had never had oedema (mean age 63 (1) years, FEV1 1.07 (0.09) 1, PaO2 8.6 (0.4) kPa, and PaCO2 5.3 (0.2) kPa). All patients were studied fasting and after diuretics had been stopped for three days. No supplemental oxygen was given. RESULTS: The mean four hourly urine sodium excretion was less in the patients who had oedema (27 (4.6) mmol, 13% of the intravenous load) than in those without oedema (82 (15.5) mmol, 43% of the load). Initial mean plasma atrial natriuretic peptide values were significantly higher in the patients with cor pulmonale (19.1 (1.6) compared with 10.2 (0.7) pmol/l) and the mean peak rise in atrial natriuretic peptide after the intravenous saline load had been given was 13 (8.0) pmol/l in the patients with cor pulmonale and 5.5 (2.3) pmol/l in the controls. There were no significant differences in plasma and urinary osmolality, blood pressure, or creatinine clearance between the groups. CONCLUSION: Patients with chronic obstructive

  19. The New England Journal of Medicine, CorSalud and Cardiovascular Disease The New England Journal of Medicine, CorSalud y las enfermedades cardiovasculares

    Directory of Open Access Journals (Sweden)

    Francisco Luis Moreno Martínez

    2012-03-01

    Full Text Available In order to commemorate the 200th anniversary of The New England Journal of Medicine, the working staff of CorSalud extends its congratulations to this prestigious medical journal. It has been demonstrated the important role this journal played by increasing scientific knowledge, specifically in the specialty of Cardiology and,of course, its editorial quality, based not only on experience but also on professionalism. All this places it as a paradigm to be followed by each and all of the journals in the medical and scientific community.Con motivo del aniversario 200 de The New England Journal of Medicine, el colectivo de CorSalud hace llegar su felicitación a esa prestigiosa publicación médica. Queda manifiesto el importante papel que ha tenido esa revista en el incremento del conocimiento científico, específicamente en la especialidad de Cardiología; y desde luego, su calidad editorial, basadas no solo en experiencia sino también en profesionalismo, la sitúan como paradigma a seguir por todas y cada una de las revistas de la comunidad científica médica.

  20. Evaluation of Base Station CORS UDIP and CSEM for monitoring Ground Deformation Sayung Demak Indonesia

    Science.gov (United States)

    Yuwono, B. D.; Awaluddin, M.; Kun, F. H.; Lutfi, E. R.

    2017-12-01

    Sayung is a subdistrict in Demak Regency which is located on the north coast is very vulnerable to natural disasters such as rob flood, abrasion and deformation of land subsidence. The condition is suspected, among others, by several factors, among others, geological structure as a large area dominated by young alluvium layers are still experiencing compression, loading and retrieval of ground water. It is necessary to do research related to ground deformation. The geodetic method used for monitoring ground deformation by satellite surveys with GNSS. The research was conducted to observe GPS survey in 2015 and 2016. GNSS data would be processed with scientific processing GAMIT 10.6. Strategic of GPS data proccesing is the important to reach a better accuracy. The purpose of this research is to evaluate the result of calculation of coordinate value and spatial deformation obtained by both base station that is CORS UDIP and CORS CSEM for monitoring ground deformation.

  1. Contradictions within a Knotworking session of an interior décor project

    DEFF Research Database (Denmark)

    Rasmussen, Mai; Jensen, Rasmus Lund; Svidt, Kjeld

    In recent research of the construction industry, collaboration is referred to as a crucial aspect to deliver a project on time, within the predetermine budget and according to the expected level of detail (Bishop et al. 2008). This presentation will give an introduction to Knotworking as a method...... for collaboration among actors with various historical backgrounds. Knotworking is an Activity Theory based method developed by CRADLE at University of Helsinki on the basis of the method Big Room (CRADLE 2015). The agenda of Knotworking is to untie ‘knots’ within a specific project in a collaboration of various...... actors with an interest in the specific ‘knot’ (Engeström 2008). Moreover this presentation presents an analysis of contradictions within a Knotworking session of an interior décor project. The interior décor project is targeted a new building for Department of Civil Engineering at Aalborg University...

  2. Harmonia cromática em animações: a cor no contexto da tecnologia

    OpenAIRE

    Franck, Gláucia

    2015-01-01

    Esta dissertação busca demonstrar a influência recíproca entre a arte e a tecnologia para além do artefato com o uso da cor na obtenção da harmonia cromática e do reforço perceptivo visual e cultural. Procuramos evidenciar como a arte se apropria da tecnologia na obtenção da harmonia pelo uso da cor no processo criativo. A arte, ao ser mediada pela tecnologia, desafia o artista a opor-se ao determinismo tecnológico que impõe resultados pela estandardização do uso de seus aparatos, superando s...

  3. Noninvasive method to assess cor pulmonale in patients with chronic obstructive pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Yamaoka, S.; Yonekura, Y.; Koide, H.; Ohi, M.; Kuno, K.

    1987-07-01

    In our study of 15 patients with chronic obstructive pulmonary disease, we performed myocardial perfusion single-photon-emission computerized tomography (SPECT) with thallium-201 to quantitatively assess right ventricular hypertrophy. On the SPECT images, we determined the ratio of activity in the right-to-left ventricular wall as the thallium score. Right ventricular ejection fraction (RVEF) was measured by multigated equilibrium radionuclide ventriculography with krypton-81m. Both the thallium scores and RVEF values correlated well with pulmonary arterial pressure (r = 0.65 and r = -0.86, respectively) and permitted the structural and functional assessment of cor pulmonale. When the patients were classified according to the thallium scores and RVEF values, those who had both a high thallium score and reduced RVEF had a significantly high pulmonary arterial pressure and vice versa. The combined evaluation of the thallium score and RVEF enabled accurate noninvasive assessment of cor pulmonale.

  4. An unusual cause of acute cor pulmonale – Significance of the ‘continuous diaphragm sign’

    Science.gov (United States)

    Mohanan, Sandeep; Sajeev, C.G.; Muneer, Kader; Rajesh, G.; Krishnan, M.N.; Pillai, Vivek

    2014-01-01

    A patient presented with chest pain and clinical features of acute right heart failure. Initial work up revealed the presence of severe PAH. Acute pulmonary embolism is the commonest and most life-threatening cause for acute cor pulmonale. Even though the clinical picture suggested pulmonary embolism, a subtle sign was missed from the first chest X-ray taken in the emergency department. However on reanalysis the ‘continuous diaphragm sign’ later guided us towards the diagnosis. Our case represents one of the first reports of a rare etiology for acute cor pulmonale – hypersensitivity pneumonitis. Right ventricular dysfunction was caused by an acute rise in pulmonary artery pressures as well as by the compressive effects of pneumomediastinum. We emphasize the role played by a good quality chest X-ray early in the management of acute chest pain syndromes. However pulmonary embolism should be ruled out conclusively before redirecting attention to less malignant conditions. PMID:25443610

  5. Echocardiographic findings in a goat with cor pulmonale secondary to chronic parasitic pneumonia.

    Science.gov (United States)

    Buczinski, S; Pinard, J; Ferrouillet, C; Veillette, M

    2010-02-01

    A four-year old goat was presented for anorexia and apathy since kidding one week earlier. Physical examination revealed dyspnea, extensive ascites and bilateral distended jugular veins, suggestive of congestive right heart failure. The echocardiographic findings of severe right ventricular and atrial dilatation were consistent with right heart failure. In the absence of abnormalities in the right ventricular outflow tract a diagnosis of cor pulmonale secondary to lung disease was posed. Due to a poor prognosis, the goat was euthanized. Necropsy confirmed cor pulmonale and identified severe chronic parasitic pneumonia as underlying cause. Echocardiography is an interesting tool also applicable in the farm for diagnosing heart diseases in goats, and its use should help to avoid unnecessary therapy in cases with a poor prognosis.

  6. Inventory of Continuously Operating Reference Stations (CORS) in the northern Gulf of Mexico (2016) (NCEI Accession 0159588)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains information about continuously operating reference stations (CORS) and the networks that they belong to throughout the Gulf of Mexico region,...

  7. [Alterations in intraocular pressure and the CorVis parameters after LASIK].

    Science.gov (United States)

    Anton, A; Neuburger, M; Jordan, J F; Wecker, T; Lübke, J; Heinzelmann, S; Lapp, T; Böhringer, D; Reinhard, T; Maier, P

    2017-05-01

    The reduction of corneal thickness following laser-assisted in-situ keratomileusis (LASIK) requires a correction of intraocular pressure (IOP) measurements. The corneal visualization Scheimpflug technology (CorVis ST, Oculus, Wetzlar, Germany) not only measures the IOP and central corneal thickness (CCT) but also determines 10 additional corneal parameters, such as the time to first and second applanation and velocity. Besides CCT we compared various corneal parameters before and after LASIK in order to detect possible correlations and to correct IOP measurements. Measurements with CorVis ST were made before and after LASIK in 45 myopic patients (45 left eyes). We compared the IOP and CorVis ST parameters using a paired t‑test before and after LASIK and corrected for possible correlations in a multifactorial linear model. Finally, we correlated the changes in IOP to changes in biomechanical parameters. We observed a direct correlation between the IOP measurements and the corneal thickness. The IOP was underestimated by 0.039 mm Hg per micrometer in reduction of corneal thickness. The multifactorial linear model showed a correlation of IOP change to A2 velocity and the radius of applanation. Surgical thinning of the central cornea via LASIK demonstrated a direct correlation between corneal thickness and IOP measurements using the CorVis ST technique. Postoperative changes of the A2 velocity and the applanation radius also had a statistically significant influence on post-LASIK IOP measurements. Our findings could be useful to obtain more precise post-LASIK IOP measurements.

  8. Observations of the star Cor Caroli at the Apple Valley Workshop 2016

    Science.gov (United States)

    Estrada, Reed; Boyd, Sidney; Estrada, Chris; Evans, Cody; Rhoades, Hannah; Rhoades, Mark; Rhoades, Trevor

    2017-06-01

    Using a 22-inch Newtonian Alt/Az telescope and Celestron Micro Guide eyepiece, students participating in a workshop observed the binary star Cor Caroli (STF 1692) and found a position angle of 231.0 degrees as well as an average separation of 18.7" This observation compared favorably with the 2015 Washington Double Star published position. This project was part of Mark Brewer's Apple Valley Double Star Workshop. The results were analyzed using bias and circle error probability calculations.

  9. Pengaruh Degasser Dan Grain Refiner Terhadap Sifat Mekanik Paduan Al-Si Produk Cor

    OpenAIRE

    Yohanes, Glenn; Djamil, Sofyan

    2008-01-01

    Paduan aluminium banyak digunakan pada industri otomotif, seperti pada pembuatan velg dan komponen-komponen mesin. Studi pengaruh degasser dan grain refiner terhadap kekuatan tarik, kekuatan luluh, elongasi dan kekerasan, pada proses peleburan dibandingkan dengan atau tanpa menggunakan degasser dan grain refiner. Benda uji didapat dengan melebur blok mesin Mitsubishi L.300, menggunakan tungku listrik dan proses cor sistem cetakan terbuka. Hasil penelitian, meliputi kekuatan tarik, luluh, elon...

  10. Pengaruh Degasser dan Grain Refiner terhadap Sifat Mekanik Paduan Al-Si Produk Cor

    OpenAIRE

    Yohanes, Glenn; Djamil, Sofyan

    2009-01-01

    Paduan aluminium banyak digunakan pada industri otomotif, seperti pada pembuatan velg dan komponen-komponen mesin. Studi pengaruh degasser dan grain refiner terhadap kekuatan tarik, kekuatan luluh, elongasi dan kekerasan, pada proses peleburan dibandingkan dengan atau tanpa menggunakan degasser dan grain refiner. Benda uji didapat dengan melebur blok mesin Mitsubishi L.300, menggunakan tungku listrik dan proses cor sistem cetakan terbuka. Hasil penelitian, meliputi kekuatan tarik, luluh, elon...

  11. Ibi et cor tuum: The Twin Perils of Studium and Otium in English Renaissance Intellectual Culture

    OpenAIRE

    Obi, Gertrude

    2016-01-01

    My dissertation, “Ibi et cor tuum: The Twin Perils of Studium and Otium in English Renaissance Intellectual Culture,” investigates the ways in which the temptations posed by intellectual labor were conceptualized and navigated by English Renaissance humanists. The competition pitting the vita activa against the vita contemplativa, which every age—including ours—must resolve anew, generated a spate of writings engaging with the mixed legacy of classical and medieval Christian attitudes towards...

  12. Cor a 14, the allergenic 2S albumin from hazelnut, is highly thermostable and resistant to gastrointestinal digestion

    OpenAIRE

    Pfeifer, Sabine; Bublin, Merima; Dubiela, Pawel; Hummel, Karin; Wortmann, Judith; Hofer, Gerhard; Keller, Walter; Radauer, Christian; Hoffmann?Sommergruber, Karin

    2015-01-01

    Scope Allergens from nuts frequently induce severe allergic reactions in sensitive individuals. The aim of this study was to elucidate the physicochemical characteristics of natural Cor a 14, the 2S albumin from hazelnut. Methods and results Cor a 14 was purified from raw hazelnuts using a combination of precipitation and chromatographic techniques. The protein was analyzed using gel electrophoresis, MS, and far?UV circular dichroism (CD) analyses. The immunoglobulin E (IgE) binding of native...

  13. GNSS Positioning by CORS and EGM2008 in Jilin Province, China

    Directory of Open Access Journals (Sweden)

    Qiong Wu

    2015-12-01

    Full Text Available The Continuously Operating Reference Station (CORS technique has been widely applied in land resource management, surveying, mapping, deformation monitoring, precise navigation, etc. This article analyzed the positioning method using EGM2008 and CORS of Jilin Province, China. The vertical transformation of EGM2008 from WGS84 to China’s CGCS2000 datum and the horizontal coordinate transformation from CGCS2000 to a triangulation coordinate system were discussed. The results indicated that a local geoid with respect to CGCS2000 can be transferred from EGM2008 with the same accuracy, and the geoid correction between CGCS2000 and WGS84 varied from 0.023 m to 0.111 m. The coordinate transformation method based on the curve surface approximation method indicated that the theoretical error was less than 0.09 m in the grid within 10° longitudinal and 5° latitudinal, and less than 0.3 m in large area and 0.1 m in small area in field validation. The method proposed in this article expanded the positioning result and its application for JLCORS and other CORS with local datum.

  14. A hybrid method for damage detection and quantification in advanced X-COR composite structures

    Science.gov (United States)

    Neerukatti, Rajesh Kumar; Rajadas, Abhishek; Borkowski, Luke; Chattopadhyay, Aditi; Huff, Daniel W.

    2016-04-01

    Advanced composite structures, such as foam core carbon fiber reinforced polymer composites, are increasingly being used in applications which require high strength, high in-plane and flexural stiffness, and low weight. However, the presence of in situ damage due to manufacturing defects and/or service conditions can complicate the failure mechanisms and compromise their strength and reliability. In this paper, the capability of detecting damages such as delaminations and foam-core separations in X-COR composite structures using non-destructive evaluation (NDE) and structural health monitoring (SHM) techniques is investigated. Two NDE techniques, flash thermography and low frequency ultrasonics, were used to detect and quantify the damage size and locations. Macro fiber composites (MFCs) were used as actuators and sensors to study the interaction of Lamb waves with delaminations and foam-core separations. The results indicate that both flash thermography and low frequency ultrasonics were capable of detecting damage in X-COR sandwich structures, although low frequency ultrasonic methods were capable of detecting through thickness damages more accurately than flash thermography. It was also observed that the presence of foam-core separations significantly changes the wave behavior when compared to delamination, which complicates the use of wave based SHM techniques. Further, a wave propagation model was developed to model the wave interaction with damages at different locations on the X-COR sandwich plate.

  15. Terapêutica hormonal na coréia de Sydenham

    Directory of Open Access Journals (Sweden)

    José Geraldo Albernaz

    1957-09-01

    Full Text Available Cinco casos de coréia de Sydenham foram submetidos à terapêutica hormonal com Cortisona, Prednisona e Prednisolona; o fenobarbital e a clorpromazina foram utilizados como medicação sintomática e a Penicilina-Benzatina como profilática. Depois de analisadas as referências bibliográficas, comparados os resultados de ν;rios autores, e ajuizados os resultados obtidos em nossos casos, acreditamos poder concluir que: 1 a terapêutica hormonal da coréia de Sydenham, com o uso de ACTH, Cortisona, Prednisona ou Pred-nisclona apresenta resultados satisfatórios; 2 a Prednisona e a Prednisolona são os hormônios mais úteis no tratamento da coréia de Sydenham, sendo possível que sua associação aos salicilatos permita obter resultados ainda melhores; 3 o tratamento deve prolongar-se até o completo desaparecimento dos sintomas, as doses variando de acôrdo com a gravidade e a evolução da moléstia; 4 a terapêutica hormonal deve ser usada sem prejuízo de medicação sintomática (sedativa e profilática (antibiótica.

  16. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    Directory of Open Access Journals (Sweden)

    Gabriela Soncini Pasetto

    2013-08-01

    Full Text Available OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9% foram incluídos no estudo. Cinco (71,4% pacientes foram tratados exclusivamente com termoterapia transpupilar, em 1 (14,2% olho a crioterapia foi simultânea, 1 (14,2% suplementou braquiterapia - placa episcleral. Três (42.8% sofreram recorrência, 2 (28.5% apresentaram metástases (um óbito, 2 foram enucleados. Complicações foram encontradas em 3 olhos: dobras maculares em 2, hemorragia vítrea em 1. Nos olhos enucleados, não havia extensão extraescleral, porém células interesclerais foram identificadas. CONCLUSÃO: Termoterapia transpupilar mostra um declínio em sua eficácia e conserva os riscos de metástases em períodos mais longos de acompanhamento, sendo necessária uma definição mais exata de seu papel nos melanomas de coróide.

  17. EVOLUÇÃO DA COR DURANTE A MATURAÇÃO DAS UVAS TINTAS

    Directory of Open Access Journals (Sweden)

    Gilberto Massashi Ide

    1993-08-01

    Full Text Available Foram feitos estudos de tonalidade e intensidade de cor na película e na polpa durante o desenvolvimento e a maturação da uva das cultivares Cabernet Sauvignon, Cabernet Franc, Merlot, Pinot Noir (Vitis vinifera e Isabel (Vitis labrusca nas safras de 1990 e 1991. A tonalidade na película diminuiu acentuadamente no início do desenvolvimento das bagas estabilizando-se após a "veraison". As boas condições climáticas (baixa precipitação pluviométrica e umidade, alta insolação da safra de 1991 tiveram pouca influência sobre a tonalidade. A intensidade de cor na película aumentou durante a maturação da uva e as condições climáticas de 1991 propiciaram maior intensidade nas cultivares Cabernet Sauvignon, Cabernet Franc e Merlot pouco influindo, no entanto, nas cultivares Pinot Noir e Isabel. Na polpa houve estabilidade da intensidade de cor, porém, a tonalidade apresentou-se variável com tendência a estabilizar-se durante a maturação.

  18. Tumores de plexo coróide: estudo epidemiológico comparativo de 24 casos

    Directory of Open Access Journals (Sweden)

    Torres Luiz Fernando Bleggi

    2004-01-01

    Full Text Available Tumores derivados do plexo coróide são neoplasias raras do sistema nervoso central que acometem principalmente crianças. Este estudo apresenta uma série de 38 pacientes com tumores de origem neuroectodérmica, dentre os quais 24 possuem diagnóstico histológico e/ou imunoistoquímico de Carcinoma do Plexo Coróide (CPC. Destes, 16 eram do gênero masculino. O local predominantemente acometido foi o ventrículo lateral esquerdo. As manifestações clínicas mais freqüentes foram hidrocefalia, hipertensão intracraniana e crises convulsivas. Todos os pacientes foram submetidos a tratamento cirúrgico. Houve um óbito no per-operatório e outro no pós-operatório imediato. Nove pacientes tiveram recidiva, evoluindo a óbito em tempo médio de 12,3 meses. Sete estão vivos. Os demais casos não apresentavam dados disponíveis. Em Curitiba, o CPC tem uma alta prevalência em relação a outros tumores do plexo coróide, podendo estar relacionado a algum agente patogênico.

  19. Acute cor pulmonale due to lymphocytic interstitial pneumonia in a child with AIDS.

    Science.gov (United States)

    Moreira-Silva, Sandra Fagundes; Moreno, Linda Marly C; Dazzi, Mariana; Freire, Consuelo Maria Caiafa; Miranda, Angelica Espinosa

    2012-01-01

    Acute cor pulmonale is a clinical syndrome with signs of right-sided heart failure resulting from sudden increase of pulmonary vascular resistance. A five-year-old male, infected by human immunodeficiency virus (HIV), was admitted at the division of infectious diseases of this hospital with cough, tachydyspnea, fever, and breathing difficulty. Computed tomography scan showed ground-glass opacities, cystic lesions, and bronchiectasis. The patient had nasal flaring, intercostal and subcostal retractions, and keeled chest. Abdomen was depressible; liver was 3 cm from the right-costal border, while spleen was 6 cm from the left-costal border. Echocardiogram examinations showed signs of acute cor pulmonale characterized by pulmonary hypertension and increased right-heart chamber dimensions. DIAGNOSTICS OUTCOME: Acquired immunodeficiency syndrome (AIDS)-B3, lymphocytic interstitial pneumonia (LIP), and acute cor pulmonale. Regressions of pulmonary hypertension and of right-heart chamber were observed after 30 days of highly active antiretroviral therapy (HAART) and chloroquine therapy. AIDS should be considered in children with recurrent pneumonia that is mostly associated with LIP rather than cystic fibrosis.

  20. Evaluation of right ventricular function by 64-row CT in patients with chronic obstructive pulmonary disease and cor pulmonale.

    Science.gov (United States)

    Gao, Yan; Du, Xiangying; Liang, Lei; Cao, Lizhen; Yang, Qi; Li, Kuncheng

    2012-02-01

    The aim of this study was to investigate the clinical application value of right ventricle (RV) function measured by 64 multi-detector row CT (MDCT) in patients with chronic obstructive pulmonary disease (COPD) and cor pulmonale. Sixty-three consecutive patients with COPD and cor pulmonale were referred for electrocardiographically gated MDCT for evaluation of suspected or known coronary artery disease. Magnetic resonance imaging (MRI) for cardiac function analysis was performed on the same day. The MDCT and MRI examinations were successfully completed in 58 patients. Forty-six patients with COPD were divided into three groups according to the severity of disease by the pulmonary function test (PFT). Twelve patients diagnosed as cor pulmonale and 32 control subjects were also included. The RV function and myocardial mass (MM) were obtained by 64-MDCT and 1.5 T cardiac MRI in all of the groups. The results were compared among the groups using the Newman-Keuls method. Pearson's correlation was used to evaluate the relationship between the right ventricular ejection fraction (RVEF) and MM with the PFT results in COPD and cor pulmonale patients. The RVEF was significantly lower in patients with severe COPD and cor pulmonale than it was in those patients with mild or moderate COPD (P cor pulmonale. The assessment of right ventricular function is clinically important for evaluation of the severity of COPD, which may provide an objective basis for therapeutic strategy. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  1. SpineCor treatment for Juvenile Idiopathic Scoliosis: SOSORT award 2010 winner.

    Science.gov (United States)

    Coillard, Christine; Circo, Alin B; Rivard, Charles H

    2010-11-10

    Juvenile idiopathic scoliosis is a condition used to describe patients who are least 4 years of age but younger than 10 when the deformity is first identified. In these patients, the condition is usually progressive and those that are diagnosed at five years or younger have a high chance of progression to a large curve, with additional pulmonary and cardiac complications. The main form of conservative treatment for juvenile scoliosis is the use of a bracing system. This prospective interventional study was conducted to evaluate the effectiveness of the Dynamic SpineCor orthosis for juvenile idiopathic scoliosis as well as to evaluate the stability of the spine after the weaning point. For this study, 150 juvenile patients were treated by the SpineCor orthosis between 1993 and 2009. Of these, 67 patients had a definite outcome and 83 are still actively being treated. To determine the effectiveness of the brace the OUTCOME criteria recommended by the SRS was used. The results from our study showed that of the 67 patients with a definite outcome, 32.9% corrected their Cobb angle by at least 5° and 10.5% had a stabilization of their Cobb angle. Within the patients with a definite outcome, 37.3% of patients where recommended for surgery before authorized end of treatment. For this group of patients, surgery was postponed. Looking at the stability of the curves 2 years after the end of the treatment, we found 12.5% of the patients continued their correction without the brace being used and 71.4% remained stable. From our study we can clearly see that the effectiveness of the SpineCor orthosis in obtaining and maintaining the neuromuscular integration of the corrective movement can be achieved effectively for juvenile patients. Over 75% of all patients that finished the treatment had remained stable with a few continuing to correct their Cobb angle after the use of the SpineCor orthosis was discontinued. Our conclusion from this study is that the SpineCor orthosis is a

  2. SpineCor treatment for Juvenile Idiopathic Scoliosis: SOSORT award 2010 winner

    Directory of Open Access Journals (Sweden)

    Circo Alin B

    2010-11-01

    Full Text Available Introduction Juvenile idiopathic scoliosis is a condition used to describe patients who are least 4 years of age but younger than 10 when the deformity is first identified. In these patients, the condition is usually progressive and those that are diagnosed at five years or younger have a high chance of progression to a large curve, with additional pulmonary and cardiac complications. The main form of conservative treatment for juvenile scoliosis is the use of a bracing system. This prospective interventional study was conducted to evaluate the effectiveness of the Dynamic SpineCor orthosis for juvenile idiopathic scoliosis as well as to evaluate the stability of the spine after the weaning point. Material and Methods For this study, 150 juvenile patients were treated by the SpineCor orthosis between 1993 and 2009. Of these, 67 patients had a definite outcome and 83 are still actively being treated. To determine the effectiveness of the brace the OUTCOME criteria recommended by the SRS was used. Results The results from our study showed that of the 67 patients with a definite outcome, 32.9% corrected their Cobb angle by at least 5° and 10.5% had a stabilization of their Cobb angle. Within the patients with a definite outcome, 37.3% of patients where recommended for surgery before authorized end of treatment. For this group of patients, surgery was postponed. Looking at the stability of the curves 2 years after the end of the treatment, we found 12.5% of the patients continued their correction without the brace being used and 71.4% remained stable. Discussion From our study we can clearly see that the effectiveness of the SpineCor orthosis in obtaining and maintaining the neuromuscular integration of the corrective movement can be achieved effectively for juvenile patients. Over 75% of all patients that finished the treatment had remained stable with a few continuing to correct their Cobb angle after the use of the SpineCor orthosis was

  3. Spontaneous echo contrast of unexpected etiology.

    Science.gov (United States)

    Serban, Marinela; Ghiorghiu, Ioana; Craciunescu, Ileana; Calin, Cosmin; Platon, Pavel; Apetrei, Eduard; Ginghina, Carmen

    2006-06-01

    Cor triatriatum sinister is a rare congenital anomaly characterized by the presence of a fibromuscular membrane dividing the left atrium into two chambers: one entering the four pulmonary veins, the other connecting to the mitral valve. The extent of the communication between the two chambers and the presence of associated lesions determine the severity of symptoms and the complications. We report the case of a 20-year-old man firstly diagnosed with obstructive cor triatriatum sinister and severe pulmonary hypertension.

  4. Different Cardiac Anomalies in Mother and Son with 4q-Syndrome.

    Science.gov (United States)

    Marcì, Marcello; Guarina, Angela; Castiglione, M Cristina; Sanfilippo, Nicola

    2015-01-01

    We report a female patient with asymptomatic cor triatriatum sinister, associated with 4q34.3 deletion. Her child, carrying the same imbalance, suffers from tetralogy of Fallot. To the best of our knowledge, this is the first reported case of cor triatriatum associated with deletion of the long arm of the chromosome 4; furthermore, the majority of patients with chromosome 4 long arm syndrome have de novo deletions and only few familial cases have been reported so far.

  5. A novel cold-regulated gene from Camellia sinensis, CsCOR1, enhances salt- and dehydration-tolerance in tobacco

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xian-Wen, E-mail: xianwenli01@sina.com [College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); College of Life Science, Xinyang Normal University, Xinyang 464000 (China); Key Laboratory of Horticultural Plant Biology of the Ministry of Education, Huazhong Agricultural University, Wuhan 430070 (China); Feng, Zhi-Guo; Yang, Hui-Min; Zhu, Xiao-Pei [College of Life Science, Xinyang Normal University, Xinyang 464000 (China); Liu, Jun, E-mail: liujun@mail.hzau.edu.cn [College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070 (China); Key Laboratory of Horticultural Plant Biology of the Ministry of Education, Huazhong Agricultural University, Wuhan 430070 (China); Yuan, Hong-Yu, E-mail: yhongyu92@163.com [College of Life Science, Xinyang Normal University, Xinyang 464000 (China)

    2010-04-02

    In present research, the full-length cDNA and the genomic sequence of a novel cold-regulated gene, CsCOR1, were isolated from Camellia sinensis L. The deduced protein CsCOR1 contains a hydrophobic N-terminus as a signal peptide and a hydrophilic C-terminal domain that is rich in glycine, arginine and proline. Two internal repetitive tridecapeptide fragments (HSVTAGRGGYNRG) exist in the middle of the C-terminal domain and the two nucleotide sequences encoding them are identical. CsCOR1 was localized in the cell walls of transgenic-tobaccos via CsCOR1::GFP fusion approach. The expression of CsCOR1 in tea leaves was enhanced dramatically by both cold- and dehydration-stress. And overexpression of CsCOR1 in transgenic-tobaccos improved obviously the tolerance to salinity and dehydration.

  6. Representativeness of Participants in the Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium Relative to the Surveillance, Epidemiology and End Results (SEER) Program

    Science.gov (United States)

    Catalano, Paul J.; Ayanian, John Z.; Weeks, Jane C.; Kahn, Katherine L.; Landrum, Mary Beth; Zaslavsky, Alan M.; Lee, Jeannette; Pendergast, Jane; Harrington, David P.

    2013-01-01

    Background The research goals of the Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium are to determine how characteristics and beliefs of patients, providers, and health-care organizations influence the treatments and outcomes of individuals with newly diagnosed lung and colorectal cancers. Because CanCORS results will inform national policy, it is important to know how they generalize to the United States population with these cancers. Research Design This study assessed the representativeness of the CanCORS cohort of 10,547 patients with lung cancer (LC) or colorectal cancer (CRC) enrolled between 2003 and 2005. We compared characteristics (gender, race, age and disease stage) to the Surveillance, Epidemiology and End Results (SEER) population of 234,464 patients with new onset of these cancers during the CanCORS recruitment period. Results The CanCORS sample is well matched to the SEER Program for both cancers. In CanCORS, 41% LC / 47% CRC were female versus 47% LC / 49% CRC in SEER. African American, Hispanic and Asian cases differed by no more than 5 percentage points between CanCORS and SEER. The SEER population is slightly older, with the percentage of patients over 75 years 33.1% LC / 37.3% CRC in SEER versus 26.9% LC / 29.4% in CanCORS, and also has a slightly higher proportion of early stage patients. We also found that the CanCORS cohort was representative within specific SEER regions that map closely to CanCORS sites. Conclusions This study demonstrates that the CanCORS Consortium was successful in enrolling a demographically representative sample within the CanCORS regions. PMID:22406968

  7. Experimental and Numeral Investigation on X-cor Sandwich Structure under Low-velocity Impact

    Directory of Open Access Journals (Sweden)

    ZHU Fei

    2017-04-01

    Full Text Available X-cor sandwich is a new kind of foam sandwich reinforced by Z-pin techniques. Under low velocity impact damage, failure mechanism of X-cor sandwich structure is complex. Failure behavior of X-cor sandwich structure at different energy stages was analyzed, and the effects of the volume fraction of Z-pin implant and the density of the foam core on the failure behavior were also discussed. Z-pin diameter of specimens in low speed impact test was 0.5 mm, and the implantation angle was 22°, and the type of foam and Z-pin implant volume fraction in the experiment was variable .The results show that under 6 J impact energy, the impact energy is mainly absorbed by the panel’s delamination. The sandwich contained Z-pin is beneficial to reduce the delamination area, while the delamination area of blank sample increases by 45.1%. The foam density has little effect on the delamination area. The Z-pin fails under 12 J impact energy. The residual compressive strength ratio increases first and then decreases with the increase of volume fraction of Z-pin. The sample has the highest residual compressive strength ratio when the volume fraction reaches 0.42%. As the foam density increases, the residual compressive strength ratio increases. When the energy reaches 18 J, shear crack appears in the foam core, and the crack absorbs most of the energy. The weaker the foam core, the larger the residual compressive strength ratio is, and the more the volume fraction of Z-pin implanted, the lower the residual compressive strength ratio is. The low velocity impact model is also established by numerical simulation, and the result of impact damage is directly transferred and applied to study the residual strength model; the result obtained is 25%~29% higher than the experimental value.

  8. Usefulness of thallium-201 myocardial perfusion scintigraphy in the diagnosis of chronic cor pulmonale

    Energy Technology Data Exchange (ETDEWEB)

    Kawai, S.; Tanaka, N.; Sawada, M.; Sakaguchi, K.; Fujita, K. (Osaka Prefectural Habikino Hospital, Osaka (Japan))

    1981-09-01

    To open up the possibility of exact clinical diagnoses of chronic cor pulmonale, we performed thallium-201 myocardial perfusion scintigraphy on patients with chronic pulmonary disease. From the thallium activity in the left ventricle (plus ventricular septum) and right ventricle counted scintigraphically, we determined the thallium activity ratio of left to right ventricle (TAR). The intra- and inter-observer variations of this ratio were negligible. We compared TAR with pulmonary hemodynamic findings and with left to right ventricular mass ratio measured at autopsy, and obtained the following results. 1) Left to right ventricular mass ratio determined in 11 autopsied patients by the method of Fulton et al. was closely correlated with TAR values (r = 0.90, p < 0.001). 2) In patients with chronic pulmonary disease, there were highly significant exponential inverse correlations between TAR and pulmonary arterial mean pressure, total pulmonary vascular resistance and right ventricular systolic pressure with the coefficients of -0.75, -0.72 or -0.77, respectively (p < 0.001). These results suggested the possibility that the severity of pulmonary circulatory disturbance may be ascertained non-invasively by TAR measurement. Thus, thallium-201 myocardial perfusion scintigraphy is able to reveal non-invasively right ventricular hypertrophy in patients with chronic pulmonary disease, and it might be a useful means of clinically diagnosing chronic cor pulmonale. If TAR obtained from scintigrams is smaller than 2, the patient concerned may possibly have right ventricular hypertrophy and he or she may be diagnosed as having chronic cor pulmonale.

  9. Structural Characterization of the Allergenic 2S Albumin Cor a 14: Comparing Proteoform Patterns across Hazelnut Cultivars.

    Science.gov (United States)

    Korte, Robin; Happe, Jana; Brümmer, Ina; Brockmeyer, Jens

    2017-02-03

    The hazelnut allergen Cor a 14 belongs to the 2S albumins, a family of heterodimeric seed storage proteins exhibiting a high degree of structural diversity. Given its relevance as an allergen and the potential to elicit severe reactions, elucidation of the sequence heterogeneity of naturally occurring Cor a 14 is essential for the development of reliable diagnostics and risk evaluation. We therefore performed a comprehensive survey on the proteoforms of Cor a 14 and determined their quantitative distribution in three different hazelnut cultivars by a combinatory HPLC-HRMS approach including bottom-up and intact mass analysis. Compared with the Cor a 14 prototype sequence, we identified three sequence polymorphisms, two of the small and one of the large subunit, and elucidated their specific pairing on the protein level. Furthermore, we located a pronounced microheterogeneity on the protein termini and, for the first time, provide data on varying proteoform patterns between different cultivars of an allergenic seed. Together, these data present the basis for a more detailed investigation on the allergenicity of Cor a 14 in different cultivars and constitute, to be best of our knowledge, the largest set of proteoforms so far reported for a 2S albumin.

  10. El Corsé nocturno ISJ 3D en el tratamiento de las escoliosis

    OpenAIRE

    González Vicente, Luis

    2017-01-01

    La escoliosis más estudiada es la escoliosis idiopática del adolescente (EIA). Su etiología sigue siendo desconocida. La escoliosis es una deformidad vertebral de diversos orígenes. A pesar de que su aspecto clínico que puede ser parecido, las escoliosis de un u otro grupo etiológico pueden tener pronósticos muy dispares, por la diferente progresividad y gravedad de sus curvas. El índice de efectividad del corsé ISJ es alto en todas las curvas. El sexo no influye en los resultados. ...

  11. Estabilidade da cor de agentes cimentantes utilizados para facetas cerâmicas

    OpenAIRE

    Pinto, Greciana Bruzi Brasil

    2010-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2010 O objetivo deste estudo in vitro foi avaliar a estabilidade da cor de diferentes agentes cimentantes. Quarenta incisivos bovinos foram selecionados e tiveram suas faces proximais, incisal e a raiz seccionadas e descartadas. Para simulação do preparo, foi realizado o desgaste do esmalte vestibular com lixa de SiC #200. Os espécimes foram...

  12. The New England Journal of Medicine, CorSalud and Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Francisco Luis Moreno Martínez

    2012-03-01

    Full Text Available In order to commemorate the 200th anniversary of The New England Journal of Medicine, the working staff of CorSalud extends its congratulations to this prestigious medical journal. It has been demonstrated the important role this journal played by increasing scientific knowledge, specifically in the specialty of Cardiology and,of course, its editorial quality, based not only on experience but also on professionalism. All this places it as a paradigm to be followed by each and all of the journals in the medical and scientific community.

  13. Observations of the Star Cor Caroli at the Apple Valley Workshop 2016 (Abstract)

    Science.gov (United States)

    Estrada, R.; Boyd, S.; Estrada, C.; Evans, C.; Rhoades, H.; Rhoades, M.; Rhoades, T.

    2017-12-01

    (Abstract only) Using a 22-inch Newtonian Alt/Az telescope and Celestron Micro Guide eyepiece, students participating in a workshop observed the binary star Cor Caroli (STF 1692; alpha CVn) and found a position angle of 231.0 degrees as well as an average separation of 18.7" This observation compared favorably with the 2015 Washington Double Star published position. This project was part of Mark Brewer's Apple Valley Double Star Workshop. The results were analyzed using bias and circle error probability calculations.

  14. [Tumoral microembolism and cor-pulmonar as manifestation of hepatocelular carcinoma].

    Science.gov (United States)

    Canelo Aybar, Carlos Gilberto; Cuadra Urteaga, José Luís; Fujii, F; Romaní Romaní, Franco; Atencia Matute, Fernando Alonso; Verona Rubio, Rogger Oscar

    2008-01-01

    The tumour pulmonary micro-embolism is a rare condition characterized by the occlusion of pulmonary small arteries, arteriolas, and alveolar capillaries septales, accompanied of trombosis. Occasionally the development of pulmonary hypertension is the first manifestation of an occult neoplasia, in series of autopsies, an incidence from 3 to 26% has been reported in solid tumors, being clinical evident in 8%. Few cases have documented the development of this condition in patients with carcinoma hepatocelular, we report the case of a 16-year-old male who comes to the emergency with signs of cardiac insufficiency and cor pulmonare whose anatomopatological study confirmed a tumour massive microembolic compromise at pulmonary level and hepatocarcinoma.

  15. Design and Implementation of Large Vessel Navigation System Based on Beidou Cors

    Directory of Open Access Journals (Sweden)

    Huang Pengfei

    2017-11-01

    Full Text Available The ship’s pilot can obtain the ship auxiliary information through the navigation system, when berthing system can display the parameters such as traverse speed and distance of the ship. But most of the system data show that there are insufficient precision. Taking the CORS system to obtain the location information, data Calculation of Berthing System based on Polar Coordinate Algorithm, this paper puts forward a solution to the “dead point” of the berthing and aiding system, which has a certain reference value for the design of the ship berthing assistance system.

  16. Design and Implementation of Large Vessel Navigation System Based on Beidou Cors

    OpenAIRE

    Huang Pengfei; Liu Yang; Du Zhixiu; Chen Qilong; Chen Jinhai

    2017-01-01

    The ship’s pilot can obtain the ship auxiliary information through the navigation system, when berthing system can display the parameters such as traverse speed and distance of the ship. But most of the system data show that there are insufficient precision. Taking the CORS system to obtain the location information, data Calculation of Berthing System based on Polar Coordinate Algorithm, this paper puts forward a solution to the “dead point” of the berthing and aiding system, which has a cert...

  17. Vasculopatia polipoidal idiopática da coróide Idiopathic polypoidal choroidal vasculopathy

    Directory of Open Access Journals (Sweden)

    Rafael Ernane Andrade

    2002-06-01

    Full Text Available Objetivo: Descrever os achados da tomografia de coerência óptica, angiofluoresceinografia e indocianinografia na vasculopatia polipoidal idiopática da coróide. Métodos: Realizou-se análise criteriosa dos exames complementares de angiofluoresceinografia e indocianinografia, comumente utilizados para o diagnóstico, assim como da tomografia de coerência óptica, em quatro olhos de uma série de três pacientes com vasculopatia polipoidal idiopática da coróide. Resultados: Os quatro olhos mostraram lesões sub-retinianas vermelho-alaranjadas, sendo que dois casos apresentaram descolamento hemorrágico do epitélio pigmentado da retina, além de manifestações exsudativas e hemorrágicas associadas. A angiofluoresceinografia revelou dilatações aneurismáticas em ramificações anormais de vasos da coróide em apenas 1 caso, ao contrário da indocianinografia que claramente demonstrou as lesões em todos os casos. A tomografia de coerência óptica confirmou descolamento hemorrágico espontâneo do epitélio pigmentado da retina em 2 casos. Conclusão: A indocianinografia é o exame de escolha no diagnóstico da vasculopatia polipoidal da coróide, mas em alguns casos a associação com a tomografia de coerência óptica e angiofluoresceinografia pode ser útil no diagnóstico e seguimento.Purpose: To describe the role of the optical coherence tomography, fluorescein and indocyanine green angiography findings in the diagnosis of idiopathic polypoidal choroidal vasculopathy (IPCV. Methods: A series of four eyes of three patients thought to have IPCV were examined and evaluated by optical coherence tomography, fluorescein and indocyanine green angiographies. Results: Fluorescein angiography was highly important for the diagnosis only in case 1. Indocyanine green angiography showed a branching network of the vessels with marginal vascular dilatations in all cases. Optical coherence tomography showed hemorrhagic detachment of the retinal

  18. [Diuretic resistance and mechanical ventilation in decompensated cor pulmonale: successful treatment by slow continuous ultrafiltration].

    Science.gov (United States)

    Ries, W; Schenzer, A; Lüken, J; Ries, C; Machraoui, A

    2012-08-01

    We report on a 53-year-old male patient who presented with severe dyspnea at rest and massive volume overload because of decompensated cor pulmonale. Furthermore he suffered from stage 3 chronic kidney disease. As there was diuretics resistance and carbon dioxide narcosis, he had to be intubated and ventilated. The massive volume overload could be successfully treated with slow continuous ultrafiltration (SCUF) with removal of a volume of 27.5 l within 3 days. The SCUF therapy is an effective and gentle method to treat even an excessive volume overload based on diuretics resistance.

  19. Age-dependent sensitization to the 7S-vicilin-like protein Cor a 11 from hazelnut (Corylus avellana) in a birch-endemic region.

    Science.gov (United States)

    Verweij, M M; Hagendorens, M M; Trashin, S; Cucu, T; De Meulenaer, B; Devreese, B; Bridts, C H; De Clerck, L S; Ebo, D G

    2012-01-01

    Hazelnut (Corylus avellana) allergy exhibits age and geographically distinct sensitization patterns that have not yet been fully resolved. To study sensitization to Cor a 11 in different age groups of hazelnut-allergic patients and infants with atopic dermatitis (AD) sensitized to hazelnut in a birch-endemic region. Sera from 80 hazelnut-allergic patients, 33 infants under 1 year of age with AD (24 sensitized and 9 not sensitized to hazelnut), 32 healthy control individuals, and 29 birch pollen-allergic but hazelnut-tolerant individuals were tested for immunoglobulin (Ig) E reactivity to Cor a 11 by ImmunoCAP. IgE reactivity to Cor a 1.01, Cor a 1.04, Cor a 8, and Cor a 9 was studied by ISAC microarray. Forty patients (22 preschool children, 10 schoolchildren, and 8 adults) with systemic reactions on consumption of hazelnut were sensitized to Cor a 11 (respective rates of 36%, 40%, and 12.5%). Forty patients (6 preschool children, 10 schoolchildren, and 24 adults) reported oral allergy syndrome but only 2 of them (of preschool age) were sensitized to Cor a 11. Two (8%) of the AD infants sensitized to hazelnut showed IgE reactivity to Cor a 11. This reactivity was not observed in any of the AD infants without sensitization to hazelnut, in any of the birch-pollen allergic patients without hazelnut allergy, or in any of the healthy control individuals. Sensitization to Cor a 11 in a birch-endemic region is predominantly found in children with severe hazelnut allergy, a finding that is consistent with observations concerning sensitization to Cor a 9.

  20. The clinical significance of determination of adrenal medulla in patients with chronic cor pulmonale and analysis of its relevant factors

    International Nuclear Information System (INIS)

    Tian Yingchun; Zha Jinshun

    2002-01-01

    In order to find the function of adrenal medulla in the development of chronic cor pulmonale and the effect of smoking, anoxia and lung's work on adrenal medulla, the authors determined adrenal medulla in 63 patients with acute cor pulmonale (Group A) and 60 controls (Group B). The authors tried to find out the effect of the patients' age, course of disease, history of smoking, malfunction of lung on adrenal medulla by multiple regressive analysis. Adrenal medulla is significantly higher in Group A than that of in Group B (P 2 both contribute to the conclusion that smoking is an independent factor to affect the adrenal medulla. The study shows that the adrenal medulla in patients with cor pulmonale is higher than that of normal people, and that the level of adrenal medulla is dependent on the degree of seriousness of the disease, obstructive ventilatory disturbance and anoxia

  1. Gene Regulation and Signal Transduction in the ICE-CBF-COR Signaling Pathway during Cold Stress in Plants.

    Science.gov (United States)

    Wang, Da-Zhi; Jin, Ya-Nan; Ding, Xi-Han; Wang, Wen-Jia; Zhai, Shan-Shan; Bai, Li-Ping; Guo, Zhi-Fu

    2017-10-01

    Low temperature is an abiotic stress that adversely affects the growth and production of plants. Resistance and adaptation of plants to cold stress is dependent upon the activation of molecular networks and pathways involved in signal transduction and the regulation of cold-stress related genes. Because it has numerous and complex genes, regulation factors, and pathways, research on the ICE-CBF-COR signaling pathway is the most studied and detailed, which is thought to be rather important for cold resistance of plants. In this review, we focus on the function of each member, interrelation among members, and the influence of manipulators and repressors in the ICE-CBF-COR pathway. In addition, regulation and signal transduction concerning plant hormones, circadian clock, and light are discussed. The studies presented provide a detailed picture of the ICE-CBF-COR pathway.

  2. An escalating dose study to assess the safety, tolerability and immunogenicity of a Herpes Simplex Virus DNA vaccine, COR-1.

    Science.gov (United States)

    Dutton, Julie L; Woo, Wai-Ping; Chandra, Janin; Xu, Yan; Li, Bo; Finlayson, Neil; Griffin, Paul; Frazer, Ian H

    2016-12-01

    This paper describes a single site, open-label Phase I clinical trial evaluating the safety, tolerability and immunogenicity in healthy volunteers of a herpes simplex polynucleotide vaccine that has previously been shown to enhance immunogenicity and protect against lethal herpes simplex virus type 2 (HSV-2) challenge in mice. Five escalating doses of the vaccine, COR-1, were given by intradermal injection to HSV-1 and 2 seronegative healthy individuals. COR-1 was found to be safe and well-tolerated; the only vaccine-related adverse events were mild. While vaccine-induced antibody responses were not detectable, cell-mediated immune responses to HSV-specific peptide groups were identified in 19 of the 20 subjects who completed the study, and local inflammation at the immunisation site was observed. This study indicates COR-1 has potential to be used as a therapeutic vaccine for HSV-2 infection.

  3. [Interest of the brain natriuretic peptide as a marker of acute cor pulmonale in acute respiratory distress syndrome].

    Science.gov (United States)

    Thierry, S; Lecuyer, L; Brocas, E; Van de Louw, A; Hours, S; Moreau, M-H; Boiteau, R; Tenaillon, A

    2006-08-01

    The aim of this study was to evaluate the accuracy of the BNP as a marker of acute cor pulmonale in patients with ARDS. Prospective clinical trial. At day 2 or 3 after the onset of the ARDS, an echocardiography was performed. Patients with left ventricular dysfunction were excluded. Right ventricular area (RVA) and RVA/LVA ratio were measured. ACP was defined as RVA/LVA > 0.6 associated with septal dyskinesia. Simultaneously, 5 ml of blood was collected for BNP measurement. 26 patients were studied. BNP levels were higher in 10 patients with ACP: 585.5 [189-4830] vs 145.5 [36.5-346] pg/ml (P=0.01) but in those with creatinine clearance cor pulmonale than patients without cor pulmonale.

  4. Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA.

    Directory of Open Access Journals (Sweden)

    Chris Neale

    2015-07-01

    Full Text Available Ion channels catalyze ionic permeation across membranes via water-filled pores. To understand how changes in intracellular magnesium concentration regulate the influx of Mg2+ into cells, we examine early events in the relaxation of Mg2+ channel CorA toward its open state using massively-repeated molecular dynamics simulations conducted either with or without regulatory ions. The pore of CorA contains a 2-nm-long hydrophobic bottleneck which remained dehydrated in most simulations. However, rapid hydration or "wetting" events concurrent with small-amplitude fluctuations in pore diameter occurred spontaneously and reversibly. In the absence of regulatory ions, wetting transitions are more likely and include a wet state that is significantly more stable and more hydrated. The free energy profile for Mg2+ permeation presents a barrier whose magnitude is anticorrelated to pore diameter and the extent of hydrophobic hydration. These findings support an allosteric mechanism whereby wetting of a hydrophobic gate couples changes in intracellular magnesium concentration to the onset of ionic conduction.

  5. A cor verde do endosperma do café On the green color of coffee endosperm

    Directory of Open Access Journals (Sweden)

    Paulo Mazzafera

    1988-01-01

    Full Text Available Realizaram-se comparações entre as sementes dos cultivares Mundo Novo de Coffea arabica, cujo endosperma é verde, com as do cultivar Cera, dessa espécie, de endosperma amarelo, com o objetivo de determinar os componentes responsáveis por aquela cor. Nas análises de clorofilas, flavonóides, diterpenos totais, ácido clorogênico e íons Mg, Ca, K, Fe e B, nenhuma diferença foi verificada entre os dois cultivares, sugerindo que a coloração verde se deva à presença de outros componentes ou que o 'Cera' apresente um componente que não ocorre no 'Mundo Novo' e que inibe o desenvolvimento da cor verde no seu endosperma.A comparison was made between the green seeded Mundo Novo and the yellow seeded Cera cultivars of Coffea arabica, in order to determine the components responsible for the green color of the endosperm. Both cultivars produce beverage of good quality. Chlorophylls, flavonoids, total diterpens, chlorogenic acid, and K, Ca, Mg, Fe and B ions were determined in beans of both cultivars. No differences between cultivars were found on these component contents, what suggests that the green color may be due to other compounds or that the Cera endosperm may have an inhibitor component of the green color of the coffee beans.

  6. Lesões expansivas do plexo coróide Choroid plexus mass lesions

    Directory of Open Access Journals (Sweden)

    Ernesto Lima Araújo Melo

    2003-12-01

    Full Text Available As lesões expansivas do plexo coróide constituem um grupo bastante amplo e heterogêneo de doenças e seus simuladores. Tumores, infecções, anomalias congênitas, hemorragias, cistos e fenômenos degenerativos são alguns dos exemplos de causas de lesões expansivas do plexo coróide. No presente trabalho fizemos revisão da literatura pertinente, descrevendo os achados de imagem e ilustrando-os com alguns casos do nosso serviço. Apesar de não existir na literatura descrição de sinais patognomônicos, a avaliação criteriosa e sistemática das características das lesões pode sugerir determinada etiologia.Choroid plexus mass lesions encompass a broad and heterogeneous group of diseases and their simulators. Tumors, infections, congenital anomalies, hemorrhage, cysts and degenerative diseases are some examples of mass lesions affecting the choroid plexus. In this article we review the current literature, describing the imaging findings and illustrating choroid plexus mass lesions with some cases diagnosed at our facility. Despite the inexistence of pathognomonic signs, a careful and systematic evaluation of the imaging characteristics may suggest many etiologies.

  7. [Effect of Qishen Yiqi droplet on adenylate contents in myocardium of cor pulmonale rats].

    Science.gov (United States)

    Geng, Shi-Han; Shan, Qiu-Yue; Xu, Meng-Xi; Zhang, Yi-Dan; Song, Li-Li; Hou, Ning; Zhang, Wen; Zhang, Mi-Xia; Zhuang, Peng-Wei; Zhang, Yan-Jun

    2017-01-01

    Cor pulmonale rat models were induced by a single intraperitoneal injection of monocrotaline(MCT), and the sham group received a single intraperitioneal injection of normal saline. After the model rats received intragastric administration of Qishen Yiqi droplet(QS) for 6 weeks, the contents of adenylate(ATP, ADP and AMP) in right myocardial tissues were measured by HPLC, and then the metabolism changes in myocardium of cor pulmonale rats with QS were investigated. The results showed that ATP, ADP, and AMP were well separated, with a good linearity within a certain range of concentration; and the recovery rates were within the range of 90%-108%. As compared with model group, the level of ATP was significantly elevated in high-dose treatment group; ADP contents showed an increasing trend and AMP contents showed a decreasing trend, indicating that QS could significantly improve energy metabolism system in myocardium. By using the HPLC, a qualitative and quantitative analysis method was given for the determination of ATP, ADP and AMP contents in myocardium, providing a method for energy metabolism measurement in biological samples. Copyright© by the Chinese Pharmaceutical Association.

  8. Capturing and Processing Soil GHG Fluxes Using the LI-COR LI-8100A

    Science.gov (United States)

    Xu, Liukang; McDermitt, Dayle; Hupp, Jason; Johnson, Mark; Madsen, Rod

    2015-04-01

    The LI-COR LI-8100A Automated Soil CO2 Flux System is designed to measure soil CO2 efflux using automated chambers and a non-steady state measurement protocol. While CO2 is an important gas in many contexts, it is not the only gas of interest for many research applications. With some simple plumbing modifications, many third party analyzers capable of measuring other trace gases, e.g. N2O, CH4, or 13CO2 etc., can be interfaced with the LI-8100A System, and LI-COR's data processing software (SoilFluxPro™) can be used to compute fluxes for these additional gases. In this paper we describe considerations for selecting an appropriate third party analyzer to interface with the system, how to integrate data into the system, and the procedure used to compute fluxes of additional gases in SoilFluxPro™. A case study is presented to demonstrate methane flux measurements using an Ultra-Portable Greenhouse Gas Analyzer (Ultra-Portable GGA, model 915-0011), manufactured by Los Gatos Research and integrated into the LI-8100A System. Laboratory and field test results show that the soil CO2 efflux based on the time series of CO2 data measured either with the LI-8100A System or with the Ultra-Portable GGA are essentially the same. This suggests that soil GHG fluxes measured with both systems are reliable.

  9. Aerobic Exercise Promotes a Decrease in Right Ventricle Apoptotic Proteins in Experimental Cor Pulmonale.

    Science.gov (United States)

    Colombo, Rafael; Siqueira, Rafaela; Conzatti, Adriana; Fernandes, Tânia Regina Gattelli; Tavares, Angela Maria Vicente; Araújo, Alex Sander da Rosa; Belló-Klein, Adriane

    2015-09-01

    Pulmonary arterial hypertension is characterized by progressive increases in resistance and pressure in the pulmonary artery and Cor pulmonale. The effect of exercise on hydrogen peroxide-dependent signaling in the right ventricle (RV) of Cor pulmonale rats was analyzed. Rats were divided into sedentary control (SC), sedentary monocrotaline (SM), trained control (TC), and trained monocrotaline (TM) groups. Rats underwent exercise training (60% of VO2 max) for 5 weeks, with 3 weeks after monocrotaline injection (60 mg/kg intraperitoneally). Pulmonary resistance was enhanced in SM (2.0-fold) compared with SC. Pulmonary artery pressure was increased in SM (2.7-fold) and TM (2.6-fold) compared with their respective controls (SC and TC). RV hypertrophy indexes increased in SM compared with SC. Hydrogen peroxide was higher in SM (1.7-fold) than SC and was reduced by 47% in TM compared with SM. p-Akt was increased in TM (2.98-fold) compared with SM. The Bax/Bcl-2 ratio and caspase 3 were also increased (2.9-fold and 3.9-fold, respectively) in SM compared with SC. Caspase 3 was decreased in TM compared with SM (P < 0.05). Therefore, exercise training promoted a beneficial response by decreasing hydrogen peroxide concentrations, and consequently, apoptotic signaling in RV.

  10. An unusual cause of acute cor pulmonale--significance of the 'continuous diaphragm sign'.

    Science.gov (United States)

    Mohanan, Sandeep; Sajeev, C G; Muneer, Kader; Rajesh, G; Krishnan, M N; Pillai, Vivek

    2014-01-01

    A patient presented with chest pain and clinical features of acute right heart failure. Initial work up revealed the presence of severe PAH. Acute pulmonary embolism is the commonest and most life-threatening cause for acute cor pulmonale. Even though the clinical picture suggested pulmonary embolism, a subtle sign was missed from the first chest X-ray taken in the emergency department. However on reanalysis the 'continuous diaphragm sign' later guided us towards the diagnosis. Our case represents one of the first reports of a rare etiology for acute cor pulmonale--hypersensitivity pneumonitis. Right ventricular dysfunction was caused by an acute rise in pulmonary artery pressures as well as by the compressive effects of pneumomediastinum. We emphasize the role played by a good quality chest X-ray early in the management of acute chest pain syndromes. However pulmonary embolism should be ruled out conclusively before redirecting attention to less malignant conditions. Copyright © 2014 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

  11. Cor pulmonale due to congenital central hypoventilation syndrome presenting in adolescence.

    Science.gov (United States)

    Fine-Goulden, Miriam R; Manna, Soumendu; Durward, Andrew

    2009-07-01

    To report the first case of congenital central hypoventilation syndrome (CCHS) presenting with severe cor pulmonale in an adolescent. Case report and literature review. Our Institutional Review Board waived the need for consent. Pediatric intensive care unit in a tertiary care children's hospital. A 12-year-old girl who developed profound hypoxia following routine dental extraction under intravenous opiate sedation and became progressively obtunded due to marked hypoventilation without hypoxic arousal, requiring mechanical ventilation. She had evidence of severe right heart failure, but no cardiac, pulmonary, neurologic, or neuromuscular cause was identified. The diagnosis of CCHS was suspected and subsequently confirmed by blood polymerase chain reaction analysis that revealed a heterozygous polyalanine expansion mutation of the PHOX2B gene (five polyalanine repeats). This report describes the unusual presentation of severe cor pulmonale in an adolescent with so-called "late-onset" CCHS. CCHS was previously thought to be a disease affecting only neonates, but the late-onset phenotype has now been well described in adults. It should be considered in any child presenting with unexplained right heart failure without an identifiable cause, particularly if central sleep apnea is present, because early initiation of ventilatory support can prevent cardiac and neurologic sequelae and improve outcome.

  12. Intravenous infusion of hyperosmotic NaCl solution induces acute cor pulmonale in anesthetized rats.

    Science.gov (United States)

    Abe, Chikara; Tsuru, Yoshiharu; Iwata, Chihiro; Ogihara, Ryosuke; Morita, Hironobu

    2013-01-01

    Intravenous hyperosmotic NaCl infusion is an effective treatment for circulatory shock. However, a fast infusion rate (2 mL/kg at the rate of 1 mL/s) induces transient hypotension. This response has been reported to be due to decreased total peripheral resistance and/or decreased cardiac performance. Although the hypotension is transient and recovers within 2 min without detrimental consequences, it is important to understand the associated hemodynamics and mechanisms. We found that the hypotensive effect was larger with intravenous NaCl infusion than with intra-aortic infusion, indicating that change in cardiac performance played a more significant role than change in peripheral resistance. NaCl infusion induced an increase in pulmonary vascular resistance and central venous pressure and a decrease in right ventricular dP/dt max, suggesting acute cor pulmonale. Diastolic ventricular crosstalk-induced left ventricular failure was also observed. Hyperosmotic NaCl-induced hypotension was therefore mainly due to a combination of acute cor pulmonale and left ventricular failure.

  13. [Pathophysiological characteristics of rat pulmonary hypertension and cor pulmonale induced by monocrotaline].

    Science.gov (United States)

    Li, Jun-shan; Lng, Chao-liang; Cui, Wen-yu; Wang, Hai

    2012-05-01

    To explore the mechanism of pulmonary hypertension and Cor Pulmonale rat models induced by monocrotaline (MCT). Twenty Wistar male rats were randomly divided into normal control group and model group (n= 10), which received a single intraperitoneal injection of MCT solution (50 mg/kg , the first day) or dissolvant, respectively. On day 28 after MCT administration, the hemodynamic parameters were assessed; levels of tumour necrosis factor-alpha (TNF-alpha), nitric oxide (NO), endothelin-1 (ET-1), B-type natriuretic peptide(BNP) in pulmonary tissue or blood were measured using radio immunoassay or nitrate reductase method. 28 days after MCT injection, compared with control group, right ventricle systolic pressure (RVSP) increased and heart rate(HR), mean arterial pressure (MAP) decreased; Levels of TNF-alpha, NO, ET-1 in pulmonary tissue or blood increased significantly in MCT group. The potential mechanism of MCI- induced pulmonary hypertension and Cor Pulmonale rat models associates with increasing TNF-alpha, NO, ET-1 levels in vivo, which results from inflammatory injury of lung tissue and blood vessels induced by MCT.

  14. Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations

    Science.gov (United States)

    Rudi, Katharina; Ho, Franz Y.; Gilsbach, Bernd K.; Pots, Henderikus; Wittinghofer, Alfred; Kortholt, Arjan; Klare, Johann P.

    2015-01-01

    Ras of complex proteins (Roc) is a Ras-like GTP-binding domain that always occurs in tandem with the C-terminal of Roc (COR) domain and is found in bacteria, plants and animals. Recently, it has been shown that Roco proteins belong to the family of G-proteins activated by nucleotide (nt)-dependent dimerization (GADs). We investigated the RocCOR tandem from the bacteria Chlorobium tepidum with site-directed spin labelling and pulse EPR distance measurements to follow conformational changes during the Roco G-protein cycle. Our results confirm that the COR domains are a stable dimerization device serving as a scaffold for the Roc domains that, in contrast, are structurally heterogeneous and dynamic entities. Contrary to other GAD proteins, we observed only minor structural alterations upon binding and hydrolysis of GTP, indicating significant mechanistic variations within this protein class. Mutations in the most prominent member of the Roco family of proteins, leucine-rich repeat (LRR) kinase 2 (LRRK2), are the most frequent cause of late-onset Parkinson's disease (PD). Using a stable recombinant LRRK2 Roc-COR-kinase fragment we obtained detailed kinetic data for the G-protein cycle. Our data confirmed that dimerization is essential for efficient GTP hydrolysis and PD mutations in the Roc domain result in decreased GTPase activity. Previous data have shown that these LRRK2 PD-mutations are located in the interface between Roc and COR. Importantly, analogous mutations in the conserved C. tepidum Roc/COR interface significantly influence the structure and nt-induced conformational changes of the Roc domains. PMID:26310572

  15. Conformational heterogeneity of the Roc domains in C. tepidum Roc-COR and implications for human LRRK2 Parkinson mutations.

    Science.gov (United States)

    Rudi, Katharina; Ho, Franz Y; Gilsbach, Bernd K; Pots, Henderikus; Wittinghofer, Alfred; Kortholt, Arjan; Klare, Johann P

    2015-08-26

    Ras of complex proteins (Roc) is a Ras-like GTP-binding domain that always occurs in tandem with the C-terminal of Roc (COR) domain and is found in bacteria, plants and animals. Recently, it has been shown that Roco proteins belong to the family of G-proteins activated by nucleotide (nt)-dependent dimerization (GADs). We investigated the RocCOR tandem from the bacteria Chlorobium tepidum with site-directed spin labelling and pulse EPR distance measurements to follow conformational changes during the Roco G-protein cycle. Our results confirm that the COR domains are a stable dimerization device serving as a scaffold for the Roc domains that, in contrast, are structurally heterogeneous and dynamic entities. Contrary to other GAD proteins, we observed only minor structural alterations upon binding and hydrolysis of GTP, indicating significant mechanistic variations within this protein class. Mutations in the most prominent member of the Roco family of proteins, leucine-rich repeat (LRR) kinase 2 (LRRK2), are the most frequent cause of late-onset Parkinson's disease (PD). Using a stable recombinant LRRK2 Roc-COR-kinase fragment we obtained detailed kinetic data for the G-protein cycle. Our data confirmed that dimerization is essential for efficient GTP hydrolysis and PD mutations in the Roc domain result in decreased GTPase activity. Previous data have shown that these LRRK2 PD-mutations are located in the interface between Roc and COR. Importantly, analogous mutations in the conserved C. tepidum Roc/COR interface significantly influence the structure and nt-induced conformational changes of the Roc domains. © 2015 Authors.

  16. Small intestinal absorption in patients with chronic obstructive pulmonary disease complicated by cor pulmonale - A pilot study

    DEFF Research Database (Denmark)

    Andersen, Sara Korsgaard; Hardis, Anne L S; Tupper, Oliver Djurhuus

    2018-01-01

    BACKGROUND: Cor pulmonale is a common complication to Chronic Obstructive Pulmonary Disease (COPD), and may result in increased pressure in the inferior caval vein and stasis of the liver. The chronic pulmonary hypertension may lead to stasis in the veins from the small intestine and thereby...... compromise absorption of nutrients. AIM: To investigate whether patients with pulmonary hypertension have reduced absorption capacity compared to COPD patients without cor pulmonale. METHODS: Absorption of d-xylose (25 g) and zinc (132 mg), administered as a single dose, was tested in 14 COPD patients, seven...

  17. A novel cold-regulated gene from Phlox subulata, PsCor413im1, enhances low temperature tolerance in Arabidopsis.

    Science.gov (United States)

    Zhou, Aimin; Sun, Hongwei; Feng, Shuang; Zhou, Mi; Gong, Shufang; Wang, Jingang; Zhang, Shuzhen

    2018-01-08

    Low temperature stress adversely affects plant growth, development, and crop productivity. Analysis of the function of genes in the response of plants to low temperature stress is essential for understanding the mechanism of chilling and freezing tolerance. In this study, PsCor413im1, a novel cold-regulated gene isolated from Phlox subulata, was transferred to Arabidopsis to investigate its function under low temperature stress. Real-time quantitative PCR analysis revealed that PsCor413im1 expression was induced by cold and abscisic acid. Subcellular localization revealed that PsCor413im1-GFP fusion protein was localized to the periphery of the chloroplast, consistent with the localization of chloroplast inner membrane protein AtCor413im1, indicating that PsCor413im1 is a chloroplast membrane protein. Furthermore, the N-terminal of PsCor413im1 was determined to be necessary for its localization. Compared to the wild-type plants, transgenic plants showed higher germination and survival rates under cold and freezing stress. Moreover, the expression of AtCor15 in transgenic plants was higher than that in the wild-type plants under cold stress. Taken together, our results suggest that the overexpression of PsCor413im1 enhances low temperature tolerance in Arabidopsis. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. A Longitudinal Evaluation of the Med-COR Program's Efforts To Improve Minority Students' Postsecondary Educational Opportunities and Health Career Participation. Part A: A Retrospective Study.

    Science.gov (United States)

    Maddahian, Ebrahim

    The Medical-Counseling, Organizing, and Recruiting (Med-COR) program is a project sponsored jointly by the University of California School of Medicine and the Los Angeles Unified School District. The program, which was organized to serve 4 inner city schools, has expanded to serve 42 middle schools and 34 high schools. The Med-COR programs major…

  19. CorA, the magnesium/nickel/cobalt transporter, affects virulence and extracellular enzyme production in the soft rot pathogen Pectobacterium carotovorum.

    Science.gov (United States)

    Kersey, Caleb M; Agyemang, Paul A; Dumenyo, C Korsi

    2012-01-01

    Pectobacterium carotovorum (formerly Erwinia carotovora ssp. carotovora) is a phytopathogenic bacterium that causes soft rot disease, characterized by water-soaked soft decay, resulting from the action of cell wall-degrading exoenzymes secreted by the pathogen. Virulence in soft rot bacteria is regulated by environmental factors, host and bacterial chemical signals, and a network of global and gene-specific bacterial regulators. We isolated a mini-Tn5 mutant of P. carotovorum that is reduced in the production of extracellular pectate lyase, protease, polygalacturonase and cellulase. The mutant is also decreased in virulence as it macerates less host tissues than its parent and is severely impaired in multiplication in planta. The inactivated gene responsible for the reduced virulent phenotype was identified as corA. CorA, a magnesium/nickel/cobalt membrane transporter, is the primary magnesium transporter for many bacteria. Compared with the parent, the CorA(-) mutant is cobalt resistant. The mutant phenotype was confirmed in parental strain P. carotovorum by marker exchange inactivation of corA. A functional corA(+) DNA from P. carotovorum restored exoenzyme production and pathogenicity to the mutants. The P. carotovorum corA(+) clone also restored motility and cobalt sensitivity to a CorA(-) mutant of Salmonella enterica. These data indicate that CorA is required for exoenzyme production and virulence in P. carotovorum. © 2011 THE AUTHORS. MOLECULAR PLANT PATHOLOGY © 2011 BSPP AND BLACKWELL PUBLISHING LTD.

  20. Mixoma de átrio direito associado a cor pulmonale agudo: relato de caso Mixoma de atrio derecho asociado a cor pulmonale agudo: relato de caso Right atrial myxoma associated with acute cor pulmonale: case report

    Directory of Open Access Journals (Sweden)

    Michelle Nacur Lorentz

    2008-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Os mixomas atriais são a forma mais comum de tumor intracardíaco primário. Apesar de serem tumores de comportamento benigno, recomenda-se que sejam retirados tão logo diagnosticados devido à possibilidade de embolização do tumor com suas nefastas conseqüências. O objetivo do presente relato foi apresentar um caso de tumor intracardíaco com localização rara (intra-atrial direito que apresentou embolização intra-operatória de parte do tumor e alertar os anestesiologistas para a possibilidade dessa complicação, além de discutir a conduta anestésica. RELATO DO CASO: Paciente do sexo masculino, 42 anos, portador de grande massa em átrio direito, submetido à retirada do tumor. A indução da anestesia foi feita com etomidato, fentanil e brometo de rocurônio e a manutenção, com isoflurano e fentanil. No intra-operatório o paciente apresentou quadro de cor pulmonale agudo em virtude da embolização de parte do tumor, sendo realizadas medidas de suporte e iniciada rapidamente a circulação extracorpórea. O restante da operação transcorreu bem e o paciente recebeu alta no sétimo dia pós-operatório em boas condições. CONCLUSÕES: Apesar do mixoma intracardíaco ser um tumor de características benignas, ele pode estar associado a complicações graves e às vezes fatais. O conhecimento da doença é importante para que o anestesiologista possa manusear de modo adequado esses pacientes, bem como diagnosticar e tratar as possíveis complicações intra-operatórias.JUSTIFICATIVA Y OBJETIVOS: Los mixomas atriales son la forma más común de tumor intracardiaco primario. A pesar de ser tumores de comportamiento benigno, se recomienda que sean retirados en cuanto sean diagnosticados debido a la posibilidad de embolización del tumor con sus nefastas consecuencias. El objetivo de este relato de caso fue presentar un caso de tumor intracardiaco con localización rara (intra-atrial derecho que present

  1. InsCor: um método simples e acurado para avaliação do risco em cirurgia cardíaca InsCor: a simple and accurate method for risk assessment in heart surgery

    Directory of Open Access Journals (Sweden)

    Omar A. V. Mejía

    2013-03-01

    Full Text Available FUNDAMENTO: Escores de risco apresentam dificuldades para obter o mesmo desempenho em diferentes populações. OBJETIVO: Criar um modelo simples e acurado para avaliação do risco nos pacientes operados de doença coronariana e/ou valvar no Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP. MÉTODOS: Entre 2007 e 2009, 3.000 pacientes foram operados consecutivamente de doença coronariana e/ou valvar no InCor-HCFMUSP. Desse registro, dados de 2/3 dos pacientes foram utilizados para desenvolvimento do modelo (técnica de bootstrap e de 1/3 para validação interna do modelo. O desempenho do modelo (InsCor foi comparado aos complexos 2000 Bernstein-Parsonnet (2000BP e EuroSCORE (ES. RESULTADOS: Apenas 10 variáveis foram selecionadas: Idade > 70 anos; sexo feminino; cirurgia de revascularização coronariana + valva; infarto de miocárdio BACKGROUND: Risk scores show difficulties to attain the same performance in different populations. OBJECTIVE: To create a simple and accurate risk assessment model for patients submitted to surgery due to coronary and/or valvular disease at Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP. METHODS: Between 2007 and 2009, 3,000 patients were submitted to surgical procedure due to coronary artery and/or valvular disease at InCor-HCFMUSP. From this record, data of 2/3 of the patients were used for model development (bootstrap technique, and 1/3 for internal validation of the model. The performance of the model (InsCor was compared to the 2000 Bernstein-Parsonnet (2000BP and EuroSCORE (ES complexes. RESULTS: Only 10 variables were selected: age > 70 years, female sex; coronary revascularization + valve, myocardial infarction < 90 days; reoperation; surgical treatment of aortic valve; surgical treatment of tricuspid valve; creatinine < 2mg/dL; ejection fraction < 30%, and events. The Hosmer Lemeshow test for the InsCor was 0.184, indicating excellent calibration. The area under

  2. CorSalud, The New England Journal of Medicine, and the International Committee of Medical Journal Editors

    Directory of Open Access Journals (Sweden)

    Francisco L. Moreno-Martínez

    2016-06-01

    Full Text Available CorSalud y The New England Journal of Medicine (NEJM coincidieron por primera vez en el título de una carta al editor en 20121, en esa ocasión fue para felicitar a tan prestigiosa revista por el bicentenario de su creación.

  3. The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.

    Science.gov (United States)

    Deyaert, Egon; Kortholt, Arjan; Versées, Wim

    2017-09-01

    Roco proteins are characterized by the presence of a Roc-COR supradomain harbouring GTPase activity, which is often preceded by an LRR domain. The most notorious member of the Roco protein family is the Parkinson's disease-associated LRRK2. The Roco protein from the bacterium Chlorobium tepidum has been used as a model system to investigate the structure and mechanism of this class of enzymes. Here, the crystallization and crystallographic analysis of the LRR-Roc-COR construct of the C. tepidum Roco protein is reported. The LRR-Roc-COR crystals belonged to space group P2 1 2 1 2 1 , with unit-cell parameters a = 95.6, b = 129.8, c = 179.5 Å, α = β = γ = 90°, and diffracted to a resolution of 3.3 Å. Based on the calculated Matthews coefficient, Patterson map analysis and an initial molecular-replacement analysis, one protein dimer is present in the asymmetric unit. The crystal structure of this protein will provide valuable insights into the interaction between the Roc-COR and LRR domains within Roco proteins.

  4. [RIGHT VENTRICULAR DIASTOLIC FUNCTION AND PERIPHERAL HEMODYNAMICS IN PATIENTS WITH CHRONIC COR PULMONALE RECEIVING VARIOUS THERAPY REGIMENS].

    Science.gov (United States)

    2010-01-01

    Right ventricular diastolic function, pulmonary hemodynamics, and peripheral endothelial vasoregulatory function were studied in patients with chronic cor pulmonale during complex treatment over time. The study confirmed the vasodilatory effect of ozone therapy and amlodipine during standard therapy, which appeared as lower blood pressure and better right ventricular diastolic function.

  5. [Results of community intervention trial for chronic obstructive pulmonary diseases and chronic cor-pulmonale from 1992 to 1999].

    Science.gov (United States)

    Cheng, X; Xu, X; Zhang, Z

    2001-10-01

    To evaluate the effect of community intervention for COPD and chronic cor-pulmonale. The baseline survey of the study was carried out in 1992. The total population was randomly divided into intervention and control regions. From 1992 the comprehensive community intervention trial was conducted in the intervention region. The data of baseline study has been published elsewhere. The family inquiry was made in all baseline population, 50 percent of high risk population and 100 percent of COPD and cor pulmonale population were reexamined. Of the 3,739 subjects who should be investigated 3,316 subjects were really investigated (88.7% of responsive rate). Of 814 subjects randomly abstracted from 3,316 in intervention and control regions, the awareness rates of smoking harm to health were 95.0% and 80.0%, of how to prevent and treat COPD were 62.0% and 35.7%, of regular visit by doctors were 46.1% and 27.0% respectively. The rate of ex-smoker was 28.2% in intervention region more than that of 23% in control region (P = 0.004). Of 3,075 subjects undergone lung function test, FEV1 decrements per capita yearly were 32.0 ml and 37.9 ml (P = 0.001); FVC decrement were 42.0 ml and 48.3 ml (P = 0.012) in intervention and control regions. The prevalence increment in COPD were 5.6% and 8.0% (P = 0.03), cor-pulmonale were 3.5% and 6.7% (P = 0.02) compared to baseline survey in both regions. The mortality of cor-pulmonale were 72.9 and 95 per 100,000 per year (P = 0.0044) from 1995 to 1999. The rate of quiting smoke is significantly increased by intervention. The declination of lung function significantly decreases. The increment in prevalence of COPD and cor-pulmonale significantly decreases. The mortality of cor-pulmonale decreases significantly in intervention region. The results indicates that the comprehensive intervention in community is an important measurement for decreasing incidence of COPD and mortality of cor-pulmonale.

  6. Investigation of Potential Landsubsidence using GNSS CORS UDIP and DinSAR, Sayung, Demak, Indonesia

    Science.gov (United States)

    Yuwono, B. D.; Prasetyo, Y.; Islama, L. J. F.

    2018-02-01

    The coastal flooding induced by land subsidence is one of major social problems in the coastal area of Central Java, especially North Demak. Recent advance technology Global Navigation Satellite System Continuously Operating System (GNSS) and Differential Synthetic Aperture Radar Interferometry ( DInSAR) is already increased our capability to identify of land subsidence processes. DInSAR required not only availability of good quality input data but also rigorous approaches. In this research we used DInSAR analysis with focusing on landsubsidence phenomena. Tests were done with geodetic GPS survey with GNSS CORS UDIP as base station. Performance assessment of development method was conducted on study area affected by land subsidence. The results of this study indicate land subsidence spreads in study area with varying degrees of subsidence.

  7. Plexo coróide hipertrofiado (demonstrado angiogràficamente e hidrocefalia

    Directory of Open Access Journals (Sweden)

    Gilberto Machado de Almeida

    1964-12-01

    Full Text Available É discutido e mesmo pôsto em dúvida por alguns autores, o papel desempenhado pelo aumento de produção do líquido cefalorraqueano (LCR, na patogênese da hidrocefalia. No caso apresentado foram encontrados os seguintes elementos que indicam ser o aumento de produção do LCR a causa da hipertensão intracraniana: 1 hipertrofia dos plexos coróides sugerida pelas angiografias e confirmada pelo ato cirúrgico e necropsia; 2 ausência de bloqueio ao trânsito do LCR; 3 grande aumento do espaço subaracnói-deo, mais evidente ao nível das cisternas, inclusive inter-hemisférica e silviana.

  8. Deficiência de tiamina como causa de cor pulmonale reversível

    Directory of Open Access Journals (Sweden)

    Liana S. Coelho

    2008-07-01

    Full Text Available A deficiência de tiamina pode apresentar quatro formas clássicas de apresentação clínica: polineuropatia periférica, anorexia e fraqueza muscular (beribéri seco; insuficiência cardíaca de alto débito com sinais congestivos (beribéri úmido; beribéri associado ao choque (Shoshin beribéri e encefalopatia de Wernicke. Neste relato, descrevemos quadro sugestivo de hipertensão pulmonar grave e cor pulmonale, com estase jugular, hepatite congestiva e edema generalizado, que apresentou reversão completa após administração de tiamina.

  9. Cor pulmonale in a patient with Brown-Vialetto-Van Laere syndrome: a case report.

    Science.gov (United States)

    da Silva-Júnior, Francisco Pereira; Moura, Rafael de Deus; Rosemberg, Sérgio; Marchiori, Paulo Eurípedes; Castro, Luiz Henrique Martins

    2011-01-15

    Brown-Vialetto-Van Laere syndrome (BVVLS) is a rare neurological disease characterized by sensorineural hearing loss and multiple cranial nerve palsies, usually involving the VIIth and IXth to XIIth cranial nerves. We describe the clinical and pathological features of a 33-year-old woman with BVVLS. The patient developed progressive exertional dyspnea, with clinical and laboratory findings of right-sided heart failure and pulmonary hypertension. She developed status epilepticus in the setting of cardiac deterioration and respiratory infection, and died of cardiogenic and septic shock. Autopsy disclosed bilateral neuronal loss and gliosis in the inferior colliculi, locus coeruleus and facial and vestibular nuclei. Cor pulmonale is a complication of hypoventilation-induced hypoxia and hypercapnia and had not yet been reported in BVVLS. Copyright © 2010 Elsevier B.V. All rights reserved.

  10. Producing Coordinate Time Series for Iraq's CORS Site for Detection Geophysical Phenomena

    Directory of Open Access Journals (Sweden)

    Oday Yaseen Mohamed Zeki Alhamadani

    2018-01-01

    Full Text Available Global Navigation Satellite Systems (GNSS have become an integral part of wide range of applications. One of these applications of GNSS is implementation of the cellular phone to locate the position of users and this technology has been employed in social media applications. Moreover, GNSS have been effectively employed in transportation, GIS, mobile satellite communications, and etc. On the other hand, the geomatics sciences use the GNSS for many practical and scientific applications such as surveying and mapping and monitoring, etc. In this study, the GNSS raw data of ISER CORS, which is located in the North of Iraq, are processed and analyzed to build up coordinate time series for the purpose of detection the Arabian tectonic plate motion over seven years and a half. Such coordinates time series have been produced very efficiently using GNSS Precise Point Positioning (PPP. The daily PPP results were processed, analyzed, and presented as coordinate time series using GPS Interactive Time Series Analysis. Furthermore, MATLAB (V.2013a is used in this study to computerize GITSA with Graphic User Interface (GUI. The objective of this study was to investigate both of the homogeneity and consistency of the Iraq CORSs GNSS raw data for detection any geophysical changes over long period of time. Additionally, this study aims to employ free online PPP services, such as CSRS_PPP software, for processing GNSS raw data for generation GNSS coordinate time series. The coordinate time series of ISER station showed a +20.9 mm per year, +27.2 mm per year, and -11.3 mm per year in the East, North, and up-down components, respectively. These findings showed a remarkable similarity with those obtained by long-term monitoring of Earth's crust deformation and movement based on global studies and this highlights the importance of using GNSS for monitoring the movement of tectonic plate motion based on CORS and online GNSS data processing services over long period of

  11. High plasma brain natriuretic peptide levels in stable COPD without pulmonary hypertension or cor pulmonale.

    Science.gov (United States)

    Inoue, Yuzuru; Kawayama, Tomotaka; Iwanaga, Tomoaki; Aizawa, Hisamichi

    2009-01-01

    Early diagnosis of chronic obstructive pulmonary disease (COPD) with latent pulmonary hypertension (PH) and cor pulmonale is important because the prognosis of this condition is poor. To investigate the utility of brain natriuretic peptide (BNP) for prognostication of COPD, plasma BNP was measured in patients with COPD without symptoms or physical findings of PH or cor pulmonale. Plasma BNP was measured in 60 patients with COPD, 10 asthmatics, and 30 healthy subjects. Echocardiography, arterial blood gas analysis, and spirometry were also performed. Mortality and exacerbation were compared between COPD patients with high and low plasma BNP levels over a 3-year follow-up period. Plasma BNP (mean +/- SEM, pg/mL) in COPD patients (41.0+/-6.6) was significantly higher than in normal subjects (14.8+/-2.7) and asthmatics (17.4+/-4.5) (p<0.0001 and p<0.05, respectively). No significant correlations were observed between plasma BNP level and pulmonary function or hypoxia. There was, however, a significant correlation between plasma BNP level and % ejection fraction (r=-0.41, p=0.0197) and pulmonary artery systolic pressure (r=0.5, p=0.004). The period until initial COPD exacerbation in subjects with a high plasma BNP level was significantly shorter (p<0.05). Plasma BNP level during exacerbations (79.9+/-16.2) was also significantly higher than during stable disease (41.2+/-8.7) (p=0.004). We suggest that plasma BNP is a non-invasive biomarker that can be used as a screening parameter for latent PH and left ventricular dysfunction, and also as a predictor of exacerbation in stable COPD.

  12. Quantitative evaluation of right ventricular overload in cor pulmonale using sup 201 Tl myocardial SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Hiroshi; Misawa, Toshihiro; Kutsumi, Yasunori (Fukui Medical School, Matsuoka (Japan)) (and others)

    1991-01-01

    To determine quantitatively the discriminant and characteristics of cor pulmonale, {sup 201}Tl myocardial perfusion SPECT was performed in 16 patients with chronic obstructive pulmonary disease (COPD) and 7 with restrictive pulmonary disease (RPD). One section of the short-axis SPECT image in which the right ventricle was most clearly visualized was selected. Tl-score was defined as the ratio of the sum of counts in the region of interest (ROI) at the anterior, mid, and posterior regions of the right ventricular free wall to the sum of counts in ROI at the posterior, lateral, and anterior walls of the left ventricle, and the anterior and posterior regions of the interventricular septum. In the group of COPD patients, Tl-score was positively correlated with mean pulmonary arterial pressure (mPAP), total pulmonary vascular resistance (TPR), and arterial carbon dioxide tension (PaCO{sub 2}), while it was inversely correlated with arterial oxygen tension (PaO{sub 2}). However, there was no significant correlation between Tl-score and mPAP, TPR, PaCO{sub 2}, and PaO{sub 2} in the group of RPD patients. In assessing pulmonary hypertension as defined by mPAP over 20 mmHg, a Tl-score greater than 0.25 was useful with a sensitivity of 69% and a specificity of 90%. The occurrence of cor pulmonale is a major factor in determining the prognosis of COPD patients. It was concluded that {sup 201}Tl myocardial SPECT is useful for evaluating right ventricular overload quantitatively, as well as for assessing core pulmonale, especially in COPD patients, since the ratio of Tl counts in the right and left ventricles was significantly correlated with right cardiopulmonary hemodynamic parameters. (N.K.).

  13. Cor pulmonale parvus in chronic obstructive pulmonary disease and emphysema: the MESA COPD study.

    Science.gov (United States)

    Kawut, Steven M; Poor, Hooman D; Parikh, Megha A; Hueper, Katja; Smith, Benjamin M; Bluemke, David A; Lima, João A C; Prince, Martin R; Hoffman, Eric A; Austin, John H M; Vogel-Claussen, Jens; Barr, R Graham

    2014-11-11

    The classic cardiovascular complication of chronic obstructive pulmonary disease (COPD) is cor pulmonale or right ventricular (RV) enlargement. Most studies of cor pulmonale were conducted decades ago. This study sought to examine RV changes in contemporary COPD and emphysema using cardiac magnetic resonance (CMR) imaging. We performed a case-control study nested predominantly in 2 general population studies of 310 participants with COPD and control subjects 50 to 79 years of age with ≥10 pack-years of smoking who were free of clinical cardiovascular disease. RV volumes and mass were assessed using magnetic resonance imaging. COPD and COPD severity were defined according to standard spirometric criteria. The percentage of emphysema was defined as the percentage of lung regions <-950 Hounsfield units on full-lung computed tomography; emphysema subtypes were scored by radiologists. Results were adjusted for age, race/ethnicity, sex, height, weight, smoking status, pack-years, systemic hypertension, and sleep apnea. Right ventricular end-diastolic volume (RVEDV) was reduced in COPD compared with control subjects (-7.8 ml; 95% confidence interval: -15.0 to -0.5 ml; p = 0.04). Increasing severity of COPD was associated with lower RVEDV (p = 0.004) and lower RV stroke volume (p < 0.001). RV mass and ejection fraction were similar between the groups. A greater percentage of emphysema also was associated with lower RVEDV (p = 0.005) and stroke volume (p < 0.001), as was the presence of centrilobular and paraseptal emphysema. RV volumes are lower without significant alterations in RV mass and ejection fraction in contemporary COPD, and this reduction is related to the greater percentage of emphysema on computed tomography. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  14. A case report of cor pulmonale in a woman without exposure to tobacco smoke: an example of the risks of indoor wood burning.

    Science.gov (United States)

    Opotowsky, Alexander R; Vedanthan, Rajesh; Mamlin, Joseph J

    2008-01-29

    We present the case of a 67-year-old woman with chronic cor pulmonale. She never smoked tobacco and had no other risk factors for pulmonary disease. In developed nations, chronic obstructive lung disease and cor pulmonale are overwhelmingly associated with tobacco use. However, indoor air pollution, most commonly due to burning of solid biomass fuel such as wood, can cause similar clinical syndromes. At our teaching hospital, there is an epidemic of chronic cor pulmonale among nonsmoking women. We attribute this sex predilection to women's greater exposure to wood smoke. Physicians must be cognizant of its risks and counsel patients on prevention strategies such as improved ventilation.

  15. Termoterapia transpupilar em melanoma maligno da coróide Transpupillary thermotherapy for malignant choroidal melanoma

    Directory of Open Access Journals (Sweden)

    Martha M. Motomo Chojniak

    2001-04-01

    Full Text Available Objetivo: Vários métodos vem sendo utilizados para o tratamento dos melanomas da coróide. A proposta deste trabalho preliminar é avaliar a eficácia da termoterapia transpupilar (TTT como tratamento primário de melanomas da coróide pequenos. Métodos: Foi realizado um trabalho prospectivo e não-randomizado para avaliar os aspectos clínicos, resposta do tumor, complicações e resultados visuais de pacientes portadores de melanomas da coróide pequenos (até 4,0 mm de espessura e 12 mm de diâmetro basal tratados por termoterapia transpupilar utilizando-se sucessivas aplicações de laser diodo contínuo de 810 nm. Resultados: Foram tratados 11 pacientes portadores de melanomas da coróide pequenos. O tumor era único e pigmentado em 100% dos casos. Crescimento documentado esteve presente em 5 pacientes (45,45% previamente ao tratamento e fatores de risco para crescimento ou metástase estavam presentes em todos os pacientes. O tempo de seguimento destes pacientes a partir do tratamento foi em média de 5,72 meses (3 - 8 meses. Foram utilizadas 3 sessões de laser em 5 pacientes (45,45% e 4 sessões em 6 pacientes (64,64%. As lesões apresentavam, por ocasião do diagnóstico, uma espessura média de 2,65 mm (1,85-3,86 mm, com maior diâmetro basal médio de 7,98 mm (4,2-11,33 mm. Após o tratamento, a espessura média foi de 1,83 mm (0,98-2,93 mm e o maior diâmetro basal médio foi de 6,59 mm (3,81 mm -10,67 mm. Das lesões tratadas, 100% apresentaram diminuição da altura e do máximo diâmetro basal, tendo sido a diminuição média da espessura de 0,89 mm e do máximo diâmetro basal de 1,39 mm. A acuidade visual manteve-se inalterada em 5 casos (45,45% e piorou após o tratamento em 6 casos (54,54%. Ocorreram complicações em 9 casos, tendo sido considerada complicação grave 1 caso de descolamento parcial da retina (9,09%; as outras complicações foram consideradas leves: pequenas hemorragias intra-retinianas em 7 pacientes (63

  16. Small intestinal absorption in patients with chronic obstructive pulmonary disease complicated by cor pulmonale - A pilot study.

    Science.gov (United States)

    Andersen, S K; Hardis, A L S; Tupper, O D; Soja, A M B; Nilsson, B; Ulrik, C S; Andersen, J R

    2018-04-01

    Cor pulmonale is a common complication to Chronic Obstructive Pulmonary Disease (COPD), and may result in increased pressure in the inferior caval vein and stasis of the liver. The chronic pulmonary hypertension may lead to stasis in the veins from the small intestine and thereby compromise absorption of nutrients. To investigate whether patients with pulmonary hypertension have reduced absorption capacity compared to COPD patients without cor pulmonale. Absorption of d-xylose (25 g) and zinc (132 mg), administered as a single dose, was tested in 14 COPD patients, seven with and seven without cor pulmonale. The presence of cor pulmonale was determined by echocardiography. The concentration of d-xylose and zinc were measured in peripheral blood one, two and three hours after ingestion and used as markers of absorption. Furthermore, urine was collected for five hours to determine the amount of excreted d-xylose. No significant difference in absorption of d-xylose (p = 0.28) or zinc (p = 0.51) was found between the two groups. However, a trend towards a delay in d-xylose absorption, as assessed by time-to-peak concentration, was observed in patients with cor pulmonale (p = 0.08). There was no significant difference in the amount of excreted d-xylose in the urine between the groups (p = 0.52). No correlation was found between the tricuspid regurgitation gradient and the absorption of both test-markers (rs = 0.34 and rs = -0.25). Likewise, no correlations were found between the inferior caval pressure during the in- and expiration phases and the absorption of d-xylose (rs = -0.09 rs = 0.23) or zinc (rs = -0.39, rs = -0.39). We found no indications that small intestinal absorption is affected in a clinically relevant degree in patients with cor pulmonale. Copyright © 2018. Published by Elsevier Ltd.

  17. «Aliis cor ipsum animus videtur»: cor у латинских авторов

    OpenAIRE

    Макарова, Виолетта

    2008-01-01

    Представлен опыт анализа лексической семантики латинского слова cor (сердце). Выявлены релевантные признаки лексемы cor, составляющие ее семантическую характеристику.

  18. Computation of Estonian CORS data using Bernese 5.2 and Gipsy 6.4 softwares

    Science.gov (United States)

    Kollo, Karin; Kall, Tarmo; Liibusk, Aive

    2017-04-01

    GNSS permanent station network in Estonia (ESTREF) was established already in 2007. In 2014-15 extensive reconstruction of ESTREF was carried out, including the establishment of 18 new stations, change of the hardware in CORS stations as well as establishing GNSS-RTK service for the whole Estonia. For GNSS-RTK service one needs precise coordinates in well-defined reference frame, i.e., ETRS89. For long time stability of stations and time-series analysis the re-processing of Estonian CORS data is ongoing. We re-process data from 2007 until 2015 with program Bernese GNSS 5.2 (Dach, 2015). For the set of ESTREF stations established in 2007, we perform as well computations with GIPSY 6.4 software (Ries et al., 2015). In the computations daily GPS-only solution was used. For precise orbits, final products from CODE (CODE analysis centre at the Astronomical Institute of the University of Bern) and JPL (Jet Propulsion Laboratory) for Bernese and GIPSY solutions were used, respectively. The cut-off angle was set to 10 degrees in order to avoid near-field multipath influence. In GIPSY, precise point positioning method with fixing ambiguities was used. Bernese calculations were performed based on double difference processing. Antenna phase centers were modelled based on igs08.atx and epnc_08.atx files. Vienna mapping function was used for mapping tropospheric delays. For the GIPSY solution, the higher order ionospheric term was modelled based on IRI-2012b model. For the Bernese solution higher order ionospheric term was neglected. FES2004 ocean tide loading model was used for the both computation strategies. As a result, two solutions using different scientific GNSS computation programs were obtained. The results from Bernese and GIPSY solutions were compared, using station repeatability values, RMS and coordinate differences. KEYWORDS: GNSS reference station network, Bernese GNSS 5.2, Gipsy 6.4, Estonia. References: Dach, R., S. Lutz, P. Walser, P. Fridez (Eds); 2015

  19. Skeletal Muscle Regeneration in a Rat (Rattus norvegicus) Model with CorMatrix and Adipose Derived Stem Cells

    Science.gov (United States)

    2015-07-16

    Model with CorMatrix and Adipose Derived Stem Cells ." PRINCIPAL INVESTIGATOR (Pl) I TRAINING COORDINATOR (TC): Major Lucas Neff DEPARTMENT...ability of the matrix to work in concert with adipose derived stem cells for further augmentation of healing. 3 FDGXXX Attachments: Attachment 1...Introduction: The increasing use of explosive devices has led to a dramatic increase in traumatic injury accompanied by severe tissue trauma and

  20. One-year prognosis and the role of brain natriuretic peptide levels in patients with chronic cor pulmonale.

    Science.gov (United States)

    Park, So Young; Lee, Chang Youl; Kim, Changhwan; Jang, Seung Hun; Park, Yong Bum; Park, Sunghoon; Hwang, Yong Il; Lee, Myung Goo; Jung, Ki-Suck; Kim, Dong-Gyu

    2015-04-01

    Data on the clinical outcomes and role of brain natriuretic peptide (BNP) levels in patients with chronic cor pulmonale are limited. A total of 69 patients with chronic cor pulmonale, admitted for dyspnea (January 2007 to September 2011) to three university hospitals, were retrospectively reviewed. All of the patients had right ventricular (RV) dysfunction on echocardiography. The median age was 70.0 yr, and chronic obstructive pulmonary disease (40.6%) and tuberculosis-destroyed lung (TDL, 27.5%) were the leading causes of chronic cor pulmonale. At the 1-yr follow-up, the mortality rate was 15.9%, and the readmission rate was 53.7%; patients with TDL had higher mortality (31.6% vs. 10.0%; P=0.059) and readmission rates (78.9% vs. 43.8%; P=0.009) than those with non-TDL diseases. The area under the receiver operating characteristic curve for admission BNP levels to predict readmission was 0.788 (95% confidence interval [CI], 0.673-0.904), and the sensitivity and specificity of the cut-off value were 80.6% and 77.4%, respectively. In multivariate analysis, high admission BNP levels were a significant risk factor for subsequent readmission (hazard ratio, 1.049; 95% CI, 1.005-1.094). Additionally, admission BNP levels were well correlated with cardiac troponin I (r=0.558), and delta BNP also correlated with delta RV systolic pressure (n=25; r=0.562). In conclusion, among hospitalized patients with chronic cor pulmonale, admission high BNP levels are a significant risk factor for subsequent readmission. Therefore, more intensive monitoring and treatment are needed in patients with higher BNP levels.

  1. Complementary gain modifications of the cervico-ocular (COR) and angular vestibulo-ocular (aVOR) reflexes after canal plugging.

    Science.gov (United States)

    Yakushin, Sergei B; Kolesnikova, Olga V; Cohen, Bernard; Ogorodnikov, Dmitri A; Suzuki, Jun-Ichi; Della Santina, Charles C; Minor, Lloyd B; Raphan, Theodore

    2011-05-01

    To determine whether the COR compensates for the loss of aVOR gain, independent of species, we studied cynomolgus and rhesus monkeys in which all six semicircular canals were plugged. Gains and phases of the aVOR and COR were determined at frequencies ranging from 0.02 to 6 Hz and fit with model-based transfer functions. Following canal plugging in a rhesus monkey, the acute stage aVOR gain was small and there were absent responses to thrusts of yaw rotation. In the chronic state, aVOR behavior was characterized by a cupula/endolymph time constant of ≈ 0.07 s, responding only to high frequencies of head rotation. COR gains were ≈ 0 before surgery but increased to ≈ 0.15 at low frequencies just after surgery; the COR gains increased to ≈ 0.4 over the next 12 weeks. Nine weeks after surgery, the summated aVOR + COR responses compensated for head velocity in space in the 0.5-3 Hz frequency range. The gains and phases continued to improve until the 35th week, where the combined aVOR + COR stabilized with gains of ≈ 0.5-0.6 and the phases were compensatory over all frequencies. Two cynomolgus monkeys operated 3-12 years earlier had similar frequency characteristics of the aVOR and COR. The combined aVOR + COR gains were ≈ 0.4-0.8 with compensatory phases. To achieve gains close to 1.0, other mechanisms may contribute to gaze compensation, especially with the head free. Thus, while there are individual variations in the time of adaptation of the gain and phase parameters, the essential functional organization of the adaption to vestibular lesions is uniform across these species.

  2. Cor a 14, Hazelnut-Specific IgE, and SPT as a Reliable Tool in Hazelnut Allergy Diagnosis in Eastern Mediterranean Children.

    Science.gov (United States)

    Buyuktiryaki, Betul; Cavkaytar, Ozlem; Sahiner, Umit M; Yilmaz, Ebru Arik; Yavuz, S Tolga; Soyer, Ozge; Sekerel, Bulent E; Tuncer, Ayfer; Sackesen, Cansin

    2016-01-01

    Improving the diagnostic efficacy of laboratory tests might reduce the need for oral food challenges and facilitate our daily practice. We aimed to determine cutoff values and probability curves, as well as to investigate the role of component-resolved diagnosis in predicting clinical reactivity in children with hazelnut allergy and to evaluate the association with pollen sensitivity. A total of 56 children with hazelnut allergy who underwent double-blind placebo-controlled food challenge and 8 children who experienced anaphylaxis after accidental hazelnut intake were included. Serum IgE levels to hazelnut extract, Cor a 1, Cor a 8, Cor a 9, Cor a 14, and Bet v 1 were measured with the ImmunoCAP system. Skin prick tests (SPT) with hazelnut, other implicated foods, and aeroallergens were performed. The optimal cutoff levels for hazelnut sIgE and SPT wheal diameter that predicted clinical reactivity with the highest sensitivity and specificity were 3.15 kU/L and 7.5 mm, respectively. Among the components, only Cor a 14 discriminated between reactive and nonreactive children. The area under curve (AUC) at the optimal cutoff point of 0.63 kU/L for Cor a 14 (0.936) was higher than the AUC of hazelnut sIgE (0.818) and SPT wheal diameter (0.803). For the first time, a 95% probability for clinical reactivity was estimated for SPT wheal diameter, IgE to hazelnut extract, and to Cor a 14 at 12 mm, 10.2 kU/L, and 1.0 kU/L, respectively. Cor a 14 was found to be a useful and reliable tool for predicting clinical reactivity in children with hazelnut allergy in the Eastern Mediterranean area. Copyright © 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  3. Comparing RTK positioning from updated REGAM and MERISTEMUM CORS networks in Southeast Spain

    Science.gov (United States)

    Giménez, Elena; Selmira Garrido, Ma; de Lacy, Ma Clara; Gil, Antonio J.

    2011-05-01

    For many countries, regional networks of Continuously Operating Reference Station (CORS) are the basic infrastructure to support the needs of users requiring positioning with centimeter-scale accuracy. However, nationwide NRTK (RTK Network) coverage is often not economically viable for countries with large rural regions. In contrast, for administrative reasons and social proximity sometimes several networks may cover the same territory. Reference station placement affects the quality of the positioning services and the cost of the network. Spain has a high density of regional NRTK networks. Indeed, the Region of Murcia has two such networks: REGAM and MERISTEMUM. REGAM uses the MAC (Master Auxiliary Concept) and MERISTEMUM uses the VRS (Virtual Reference Station), which are currently the most commonly used approaches to generate network RTK corrections. Control tests based on simultaneous determination of position have been performed in the Region of Murcia to analyze the performance of the REGAM and MERISTEMUM networks. The results confirm that both the VRS and MAC network solutions provide centimeter-scale accuracy: the positioning error for the test points inside the NRTK cells is lesser than 1.5 cm in planimetry and around 3.5 cm in height. The ambiguity resolution, the coverage and the connection to the networks services were highly satisfactory.

  4. Status of NGS CORS Network and Its Contribution to the GGOS Infrastructure

    Science.gov (United States)

    Choi, K. K.; Haw, D.; Sun, L.

    2017-12-01

    Recent advancement of Satellite Geodesy techniques can now contribute to the global frame realization needed to improve worldwide accuracies. These techniques rely on coordinates computed using continuously observed GPS data and corresponding satellite orbits. The GPS-based reference system continues to depend on the physical stability of a ground-based network of points as the primary foundation for these observations. NOAA's National Geodetic Survey (NGS) has been operating Continuously Operating Reference Stations (CORS) to provide direct access to the National Spatial Reference System (NSRS). By virtue of NGS' scientific reputation and leadership in national and international geospatial issues, NGS has determined to increase its participation in the maintenance of the U.S. component of the global GPS tracking network in order to realize a long-term stable national terrestrial reference frame. NGS can do so by leveraging its national leadership role coupled with NGS' scientific expertise, in designating and upgrading a subset of the current tracking network for this purpose. This subset of stations must have the highest operational standards to serve the dual functions: being the U.S. contribution to the international frame, along with providing the link to the national datum. These stations deserve special attention to ensure that the highest possible levels of quality and stability are maintained. To meet this need, NGS is working with the international scientific groups to add and designate these reference stations based on scientific merit such as: colocation with other geodetic techniques, geographic area, and monumentation stability.

  5. As elites de cor e os estudos de relações raciais

    Directory of Open Access Journals (Sweden)

    ANTONIO SÉRGIO ALFREDO GUIMARÃES

    1996-12-01

    Full Text Available A partir da segunda metade dos anos 30, com a visita de Herskorvitz, Franklin Frazier, Donald Pierson e Ruth Landes à Bahia, o Brasil se transforma numa espécie de laboratório de pesquisa sobre relações raciais harmoniosas. Tal condição será de certo modo reconhecida internacionalmente na década dos 50, quando a UNESCO patrocinou um ciclo de estudos sobre as relações raciais no Brasil. Os estudos realizados na Bahia, sob a coordenação, a orientação ou a influência de Thales de Azevedo se constituem hoje num acervo fundamental para as nossas ciências sociais. Nessa comunicação, reconstruo a evolução da análise de Thales de Azevedo sobre a situação racial na Bahia, partindo de seus primeiros estudos sobre o Povoamento da cidade de Salvador e seguindo-a até a sua crítica à "democracia racial" nos anos 70. Concentro-me, todavia, no seu núcleo empírico, que indiscutivelmente está em As elites de cor na Bahia, publicado em 1953.

  6. CORRECTION OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH CHRONIC COR PULMONALE BY ANGIOTENSIN II RECEPTORS ANTAGONISTS

    Directory of Open Access Journals (Sweden)

    V. S. Zadionchenko

    2007-01-01

    Full Text Available Aim. To evaluate intensity of endothelial dysfunction, processes of apoptosis, state of central and peripheral hemodynamics and to evaluate how these characteristics are influenced by angiotensin II receptors antagonists (ARA II – candesartan (Atacand and losartan (Cosaar in patients with chronic cor pulmonale (CCP at different stages of disease.Material and methods. 100 patients with chronic obstructive pulmonary disease (COPD, complicated by CCP were included into the study. Caspase activity as apoptosis induction marker, von Willebrand factor, production of nitric oxide in blood plasma and condensate of breathing out air were assessed. 70 patients received ARA II (50 patients – candesartan 4-8 mg daily, 20 patients – losartan 50-100 mg daily, 30 patients received neither ARA II nor angiotensin converting enzyme inhibitors (ACEI.Results. Significant increase in intensity of endothelial dysfunction and activation of apoptosis processes were registered according to growth of CCP severity. After 6 months of therapy von Willebrand factor decreased by 25,2% and 27,7% in candesartan and losartan groups respectively (p<0.01 for both groups. In the control group only 13.2% of von Willebrand factor reduction was seen.Conclusion. ARA II added to common therapy of COPD complicated by CCP improves functional state of endothelium restricting hyperproduction of nitric oxide and its toxic effects and slowing down apoptotic cell death.

  7. CORRECTION OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH CHRONIC COR PULMONALE BY ANGIOTENSIN II RECEPTORS ANTAGONISTS

    Directory of Open Access Journals (Sweden)

    V. S. Zadionchenko

    2015-12-01

    Full Text Available Aim. To evaluate intensity of endothelial dysfunction, processes of apoptosis, state of central and peripheral hemodynamics and to evaluate how these characteristics are influenced by angiotensin II receptors antagonists (ARA II – candesartan (Atacand and losartan (Cosaar in patients with chronic cor pulmonale (CCP at different stages of disease.Material and methods. 100 patients with chronic obstructive pulmonary disease (COPD, complicated by CCP were included into the study. Caspase activity as apoptosis induction marker, von Willebrand factor, production of nitric oxide in blood plasma and condensate of breathing out air were assessed. 70 patients received ARA II (50 patients – candesartan 4-8 mg daily, 20 patients – losartan 50-100 mg daily, 30 patients received neither ARA II nor angiotensin converting enzyme inhibitors (ACEI.Results. Significant increase in intensity of endothelial dysfunction and activation of apoptosis processes were registered according to growth of CCP severity. After 6 months of therapy von Willebrand factor decreased by 25,2% and 27,7% in candesartan and losartan groups respectively (p<0.01 for both groups. In the control group only 13.2% of von Willebrand factor reduction was seen.Conclusion. ARA II added to common therapy of COPD complicated by CCP improves functional state of endothelium restricting hyperproduction of nitric oxide and its toxic effects and slowing down apoptotic cell death.

  8. COR1 Engineering Test Unit Measurements at the Mauna Loa Solar Observatory, September 2003

    Science.gov (United States)

    Thompson, William; Reginald, Nelson; Streander, Kim

    2003-01-01

    The COR1 Engineering Test Unit (ETU), which had been previously tested at the NCAR/HAO and NRL test facilities, was modified into an instrument capable of observing the Sun. It was then taken to the Mauna Loa Solar Observatory to observe the corona. The changes made to observe the Sun were as follows: 1. The plate scale was changed to accommodate the smaller Apogee camera. This change had already been made for the NRL tests. 2. The previous Oriel polarizer was replaced with a commercial Polarcor polarizer from Newport to be more flight-like. However, because of cost and availability considerations, this polarizer was smaller than those which will be used for flight. 3. A structure was placed around the back section of the instrument, to protect it from stray light. 4. A pointing spar borrowed from HAO was used to track the Sun. A few days into the test, it became evident that some artifacts were appearing in the data, and these artifacts were changing as the polarizer was rotated. It was decided to test two other polarizers, the Oriel polarizer which had been used in the previous tests at HAO and NRL, and a Nikon polarizer which was borrowed from a camera belonging to one of the observatory staff members. These three polarizers had much different qualities are shown.

  9. Choroid plexus carcinoma in a cow Carcinoma de plexo coróide em um bovino

    Directory of Open Access Journals (Sweden)

    Fabiano José Ferreira de Sant'Ana

    2009-10-01

    Full Text Available A red, firm 3.5x3.0x3.0cm mass was found within the right lateral ventricle, compressing the hippocampus and thalamus of the brain of a 4-year-old cow. The pituitary was enlarged and firm. Histologically, both the brain and pituitary masses consisted of moderately pleomorphic epithelial cells arranged as rosettes or sheets supported by a delicate fibrovascular stroma. Based on anatomical localization, histopathological and immunohistochemical findings, a diagnosis of choroid plexus carcinoma with pituitary metastasis was made.Um massa vermelha e firme de 3,5x3,0x3,0cm foi observada no ventrículo lateral, comprimindo o hipocampo e tálamo do cérebro de uma vaca de quatro anos de idade. A pituitária estava aumentada de volume e firme. Histologicamente, tanto a massa do cérebro, quanto da pituitária, consistiam de células epiteliais moderadamente pleomórficas, arranjadas em rosetas ou cordões e apoiadas em um delicado estroma fibrovascular. Com base na localização anatômica e nos achados histopatológicos e imuno-histoquímicos, foi realizado um diagnóstico de carcinoma de plexo coróide com metástase para a pituitária.

  10. Anxiety in Patients with Chronic Cor Pulmonale and Its Effect on Exercise Capacity.

    Science.gov (United States)

    Xu, Wenxin; Yao, Jiwei; Chen, Longfei

    2016-08-01

    Chronic cor pulmonale (CCP) is a disease of increasing frequency in Chinese people and profoundly influences their health. CCP is often accompanied by anxiety and other psychological problems, and patients may show signs of motor function decline. However, little attention has been paid to the impact of CCP-related psychological problems on motor function. Patients with CCP receiving in- or outpatient treatment in the Respiratory Department of Xiangya Hospital of Central South University and the Second Xiangya Hospital of Central South University in Hunan Province between January and July 2015 were investigated. A total of 167 questionnaires were distributed, with 160 valid questionnaires ultimately collected from 95 male and 65 female participants of mean age (± standard deviation) of 68.2 ± 12.3 yr. Self-Rating Anxiety Scale (SAS) scoring was adopted to evaluate anxiety in the participants, and heart rate, blood pressure, breathing rate, 6-minute walk test and Borg index score were combined to detect the exercise capability of the participants. Anxiety was present in 48.8% of patients. Heart rate, systolic blood pressure, breathing rate and the Borg score of CCP patients with anxiety were higher than in CCP patients without anxiety ( P < 0.05), while mean walking distance was shorter ( P < 0.05). The rate of anxiety in patients with CCP is relatively high. Anxiety reduces motor function in CCP patients; therefore, in the process of treating patients with CCP, effort should be made to engage simultaneously patients in psychotherapy.

  11. Central aortic blood pressure and augmentation index: comparison between Vasotens® and SphygmoCor® technology

    Directory of Open Access Journals (Sweden)

    Rogoza AN

    2012-05-01

    Full Text Available Anatoliy N Rogoza,1 Aleksandr A Kuznetsov21Cardiology Research Complex, Moscow, Russian Federation; 2Therapy Research Institute, Siberian branch of Russian Academy of Medical Science, Novosibirsk, Russian FederationIntroduction: The aim of this study is the comparison of Vasotens® technology as used in a device with an oscillometric method of blood pressure measurement (BPLab, Petr Telegin Ltd, Nizhny Novgorod, Russian Federation against the validated tonometric system (SphygmoCor®, AtCor Medical Pty Ltd, West Ryde, Australia.Methods: The examinations were carried out in two medical centers. Exclusion criteria included atrial fibrillation, severe cardiac anomalies, heart failure, arrhythmia, decompensated diabetes, the presence of an artificial pacemaker, pregnancy, and BMI > 30. Overall, 160 patients and healthy volunteers were examined. Central aortic systolic blood pressure (aSBP and augmentation index (aAIx were obtained by means of applanation tonometry and the oscillometric method was compared.Results: aSBP and aAIx measured using the BPLab device equates significantly with the same parameters measured by SphygmoCor.Conclusion: This finding allows the recommendation of Vasotens technology, which can be used with the 24-hour BPLab monitoring system for wide clinical use.Keywords: central aortic blood pressure, augmentation index, validation, Vasotens®, BPLab®

  12. Characterization of a CorA Mg2+ transport channel from Methanococcus jannaschii using a Thermofluor-based stability assay.

    Science.gov (United States)

    Kean, James; Cleverley, Robert M; O'Ryan, Liam; Ford, Robert C; Prince, Stephen M; Derrick, Jeremy P

    2008-12-01

    The Thermofluor assay has been a valuable asset in structural genomics, providing a high-throughput method for assessing the crystallizability of proteins. The technique has been well characterized for soluble proteins but has been less extensively described for membrane proteins. Here we show the successful application of a Thermofluor-based stability assay to an ion channel, CorA from Methanococcus jannaschii. Optimization of the concentration of free detergent within the assay was important, as excessive concentrations mask the fluorescence change associated with thermal unfolding of the protein. CorA was shown to be stabilized by low pH, but relatively insensitive to salt concentration. Divalent metal cations were also capable of stabilizing the protein, in the order Co2+>Ni2+>Mn2+>Mg2+>Ca2+. Finally, removal of the oligohistidine tag was also shown to improve the thermal stability of CorA. Conclusions are drawn from this detailed study about the general applicability of this technique to other membrane proteins.

  13. StreptInCor: a candidate vaccine epitope against S. pyogenes infections induces protection in outbred mice.

    Directory of Open Access Journals (Sweden)

    Edilberto Postol

    Full Text Available Infection with Streptococcus pyogenes (S. pyogenes can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence factor, and certain regions of its N-terminus can trigger autoimmune sequelae such as rheumatic fever in susceptible individuals with untreated group A streptococcal pharyngitis. In a previous study, we utilized a large panel of human peripheral blood cells to define the C-terminal protective epitope StreptInCor (medical identity, which does not induce autoimmune reactions. We recently confirmed the results in HLA-transgenic mice. In the present study, we extended the experimental assays to outbred animals (Swiss mice. Herein, we demonstrate high titers of StreptInCor-specific antibodies, as well as appropriate T-cell immune responses. No cross-reaction to cardiac myosin was detected. Additionally, immunized Swiss mice exhibited 87% survival one month after challenge with S. pyogenes. In conclusion, the data presented herein reinforce previous results in humans and animals and further emphasize that StreptInCor could be an effective and safe vaccine for the prevention of S. pyogenes infections.

  14. Pulmonary Vascular Dysfunction and Cor Pulmonale During Acute Respiratory Distress Syndrome in Sicklers.

    Science.gov (United States)

    Cecchini, Jérôme; Boissier, Florence; Gibelin, Aude; de Prost, Nicolas; Razazi, Keyvan; Carteaux, Guillaume; Galacteros, Frederic; Maitre, Bernard; Brun-Buisson, Christian; Mekontso Dessap, Armand

    2016-10-01

    Acute chest syndrome (ACS) is the most common cause of death among sickle cell disease (SCD) adult patients. Pulmonary vascular dysfunction (PVD) and acute cor pulmonale (ACP) are common during acute respiratory distress syndrome (ARDS) and their prevalence may be even more important during ARDS related to ACS (ACS-ARDS). The objective of this study was to evaluate the prevalence and prognosis of PVD and ACP during ACS-ARDS. This was a retrospective analysis over a 10-year period of patients with moderate-to-severe ARDS. PVD and ACP were assessed by echocardiography. ARDS episodes were assigned to ACS-ARDS or nonACS-ARDS group according to whether the clinical insult was ACS or not, respectively. To evaluate independent factors associated with ACP, significant univariable risk factors were examined using logistic regression and propensity score analyses. A total of 362 patients were analyzed, including 24 ACS-ARDS. PVD and ACP were identified, respectively, in 24 (100%) and 20 (83%) ACS-ARDS patients, as compared with 204 (60%) and 68 (20%) nonACS-ARDS patients (P < 0.0001). The mortality did not differ between ACS-ARDS and nonACS-ARDS patients. Both the crude (odds ratio [OR], 19.9; 95% confidence interval [CI], 6.6-60; P < 0.0001), multivariable adjustment (OR, 27.4; 95% CI, 8.2-91.5; P < 0.001), and propensity-matched (OR, 11.7; 95% CI, 1.2-110.8; P = 0.03) analyses found a significant association between ACS-ARDS and ACP. All SCD patients presenting with moderate-to-severe ARDS as a consequence of ACS experienced PVD and more than 80% of them exhibited ACP. These results suggest a predominant role for PVD in the pathogenesis of severe forms of ACS.

  15. Acute cor pulmonale in ARDS: rationale for protecting the right ventricle.

    Science.gov (United States)

    Repessé, Xavier; Charron, Cyril; Vieillard-Baron, Antoine

    2015-01-01

    The ventilatory strategy for ARDS has been regularly amended over the last 40 years as knowledge of the pathophysiology of ARDS has increased. Initially focused mainly on the lung with the objectives of "opening the lung" and optimizing arterial oxygen saturation, this strategy now also takes into account pulmonary vascular injury and its effects on the right ventricle and on hemodynamics. Hemodynamic devices now available at the bedside, such as echocardiography, allow intensivists to evaluate respiratory settings according to right ventricular tolerance. Here, we review the pathophysiology of pulmonary vascular dysfunction in ARDS, consider the beneficial and deleterious effects of mechanical ventilation, describe the incidence and meaning of acute cor pulmonale based on recent studies in large series of patients, and propose a new, although not strictly validated, approach based on the protection of both the lung and right ventricle. One of our conclusions is that evaluating the right ventricle may help intensivists to assess the balance between recruitment and overdistension induced by the ventilatory strategy. Prone positioning with its beneficial effects on the lung and also on hemodynamics (the right ventricle) is a good illustration of this. Readers should be aware that most of the information given in this article reflects the point of view of the authors. Although based on clinical observations, clinical studies, and well-known pathophysiology, there is no evidence-based medicine to support this clinical commentary. Other approaches may be favored, in which case our article should be read as another attempt to help intensivists to improve management of ARDS.

  16. Acute cor pulmonale during protective ventilation for acute respiratory distress syndrome: prevalence, predictors, and clinical impact.

    Science.gov (United States)

    Mekontso Dessap, Armand; Boissier, Florence; Charron, Cyril; Bégot, Emmanuelle; Repessé, Xavier; Legras, Annick; Brun-Buisson, Christian; Vignon, Philippe; Vieillard-Baron, Antoine

    2016-05-01

    Increased right ventricle (RV) afterload during acute respiratory distress syndrome (ARDS) may induce acute cor pulmonale (ACP). To determine the prevalence and prognosis of ACP and build a clinical risk score for the early detection of ACP. This was a prospective study in which 752 patients with moderate-to-severe ARDS receiving protective ventilation were assessed using transesophageal echocardiography in 11 intensive care units. The study cohort was randomly split in a derivation (n = 502) and a validation (n = 250) cohort. ACP was defined as septal dyskinesia with a dilated RV [end-diastolic RV/left ventricle (LV) area ratio >0.6 (≥1 for severe dilatation)]. ACP was found in 164 of the 752 patients (prevalence of 22 %; 95 % confidence interval 19-25 %). In the derivation cohort, the ACP risk score included four variables [pneumonia as a cause of ARDS, driving pressure ≥18 cm H2O, arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2) ratio <150 mmHg, and arterial carbon dioxide partial pressure ≥48 mmHg]. The ACP risk score had a reasonable discrimination and a good calibration. Hospital mortality did not differ between patients with or without ACP, but it was significantly higher in patients with severe ACP than in the other patients [31/54 (57 %) vs. 291/698 (42 %); p = 0.03]. Independent risk factors for hospital mortality included severe ACP along with male gender, age, SAPS II, shock, PaO2/FiO2 ratio, respiratory rate, and driving pressure, while prone position was protective. We report a 22 % prevalence of ACP and a poor outcome of severe ACP. We propose a simple clinical risk score for early identification of ACP that could trigger specific therapeutic strategies to reduce RV afterload.

  17. A Novel Inflammation- and Nutrition-Based Prognostic System for Patients with Laryngeal Squamous Cell Carcinoma: Combination of Red Blood Cell Distribution Width and Body Mass Index (COR-BMI).

    Science.gov (United States)

    Fu, Yan; Mao, Yize; Chen, Shiqi; Yang, Ankui; Zhang, Quan

    Laryngeal squamous cell carcinoma (LSCC) is a head and neck cancer type. In this study, we introduced a novel inflammation- and nutrition-based prognostic system, referred to as COR-BMI (Combination of red blood cell distribution width and body mass index), for LSCC patients. A total of 807 LSCC patients (784 male and 23 female, 22-87 y of age) who underwent surgery were enrolled in this retrospective cohort study. The patients were stratified by COR-BMI into three groups: COR-BMI (0) (RDW ≤ 13.1 and BMI ≥ 25); COR-BMI (1) (RDW ≤ 13.1 and BMI 13.1 and 18.5 ≤ BMI COR-BMI (2) (RDW > 13.1 and BMI COR-BMI and cancer-specific survival (CSS) rate among LSCC patients. The 5-y, 10-y, and 15-y CSS rates were 71.6%, 60.1%, and 55.4%, respectively. There were significant differences among the COR-BMI groups in age (COR-BMI (1 versus 0: HR = 1.76; 95% CI = 0.98-3.15; 2 versus 0: HR = 2.91; 95% CI = 1.53-5.54, P = 0.001) was a significant independent predictor of CSS. COR-BMI is a novel inflammation- and nutrition-based prognostic system, which could predict long-term survival in LSCC patients who underwent surgery.

  18. The impact of exercise on derived measures of central pressure and augmentation index obtained from the SphygmoCor device.

    Science.gov (United States)

    Dawson, Ellen A; Black, Mark A; Pybis, Jennifer; Cable, N Timothy; Green, Daniel J

    2009-06-01

    The purpose of this study was to investigate whether measures derived from the SphygmoCor device and its associated transfer function are influenced by exercise-induced alterations in vascular tone. Measurements were taken from either the exercised or the contralateral nonexercised limb during repeated and identical incremental hand-grip protocols. Eight male subjects performed three 3-min bouts of hand-grip exercise on two occasions. The exercise intensities were set at 3 kg, 5 kg, with a final 1.5-kg bout performed during cuff ischemia (1.5Isch). Blood pressure waveforms were recorded from the radial artery of either the exercised or nonexercised limb using applanation tonometry (SphygmoCor) during a 90-s rest period immediately after each exercise bout. Central blood pressures and augmentation indexes (AIx), an index of arterial stiffness, were derived using the peripheral waveform and the inbuilt SphygmoCor transfer function (TF). AIx was consistently approximately 10% higher in the exercised arm during all trials compared with the nonexercised limb. Similarly, there was a consistent and significant difference ( approximately 3 mmHg; P < 0.05) between exercised and nonexercised arms for the derived central systolic and mean arterial blood pressures. Despite identical bouts of exercise, AIx and central systolic and mean arterial blood pressures derived from applanation tonometry at the peripheral radial artery were statistically different when assessed at the exercising arm vs. the nonexercising arm. Changes in vascular tone with exercise may modify the intrinsic characteristics of the vessel wall and could compromise the assumptions underlying transfer functions used to derive central measures using applanation tonometry.

  19. Expressão antigênica em carcinomas do plexo coróide humano: relato de dois casos

    Directory of Open Access Journals (Sweden)

    M. C. Almeida

    1990-09-01

    Full Text Available Neoplasias provenientes do epitélio de revestimento do plexo coróide são inco-muns, tendo sido descritos 6 padrões morfológicos. O padrão anaplásico, também denominado carcinoma do plexo coróide, é o de menor freqüência e pode dar metastases fora do SNC. A distinção histológica desses tumores, particularmente da variedade anaplásica, com outras neoplasias primárias e metastáticas no SNC pode ser difícil. O uso de técnicas imunocitoquimicas em parafina tem-se mostrado útil no esclarecimento das linhagens tumorais. Os papilomas do plexo coróide têm, no entanto, sido objeto de controvérsia, por sua complexa expressão antigênica. Usando a técnica de imunoperoxidase (sistema avidina-biotina-peroxidase pesquisaram-se, em dois casos da variedade anaplásica, os seguintes marcadores: proteína glial fibrilar ácida (GFAP com anticorpo monoclonal e policlonal; ceratinas de 40-50kDa, ceratinas de 60-70kDa (callus ceratina, enolase neuronal específica (NSE e proteína S-100, com anticorpos monoclonais. Os dois tumores mostraram positividade para NSE, proteína S-100 e ceratina de 40-50kDa; uma das duas neoplasias mostrou diferenciação glial, revelando positividade para GFAP tanto com anticorpo monoclonal quanto policlonal.

  20. Pulmonary alveolar microlithiasis with cor pulmonale: an autopsy case demonstrating a marked decrease in pulmonary vascular beds.

    Science.gov (United States)

    Terada, Tadashi

    2009-11-01

    Pulmonary alveolar microlithiasis (PAM) is a very rare autosomal recessive disorder in which microliths are formed in the alveolar space. PAM is infrequently complicated by pulmonary hypertension, the cause of which is unclear. The author in this paper found that the pulmonary hypertension was caused by a marked decrease in pulmonary vascular beds. Here, an autopsy case of PAM with a marked cor pulmonale is reported. A 14-year-old woman was found to have an abnormal pulmonary shadow, but the cause was unclear. At 24 years, she was diagnosed with a diffuse pulmonary abnormal shadow. At 42 years, she was diagnosed with PAM by imaging techniques. Her condition gradually worsened and she had to be treated with oxygen. She died of respiratory failure at 54 years. An autopsy revealed severe PAM and marked cor pulmonale. The heart weighed 360 g and right ventricular thickness was 10 mm (normal, 2-3 mm). Microscopically, the alveolar space was diffusely filled with microliths, and heart failure cells were recognized. Bone formations were scattered. The alveolar walls showed fibrous thickening, and pulmonary arteries showed atherosclerosis. The right ventricle showed marked cardiac hypertrophy. Chronic severe liver congestion was noted. A morphometric analysis using CD34-stained specimens showed a marked decrease (one tenth) in pulmonary capillary beds (capillary number: 8.6 +/- 3.1 per image), compared with normal lungs obtained from two other autopsies (85.3 +/- 9.4 and 96.2 +/- 10,3). It was concluded that the cor pulmonale and pulmonary hypertension in the present case were caused by the marked decrease of the pulmonary arterial vascular beds. More research is required regarding the etiology and treatment of PAM.

  1. Effect of sequential mechanical ventilation on cardiac function, endothelial injury and oxidative stress response in patients with cor pulmonale

    Directory of Open Access Journals (Sweden)

    Yuan-Zeng He

    2017-08-01

    Full Text Available Objective: To study the effect of sequential mechanical ventilation on cardiac function, endothelial injury and oxidative stress response in patients with cor pulmonale (CCP. Methods: Patients with cor pulmonale complicated by respiratory failure who were treated in Dongfeng People’s Hospital between May 2014 and February 2017 were selected and randomly divided into the sequential group who received sequential mechanical ventilation combined with conventional therapy and the control group who received invasive positive pressure ventilation combined with conventional therapy. The serum levels of cardiac functionrelated neurohumoral indicators, endothelial injury indicators and oxidative stress response indicators were detected before treatment as well as 3 d and 7 d after treatment. Results: 3 d and 7 d after treatment, serum NT-proBNP, Copeptin, Ang-II, ALD, ET-1, vWF, sST2 levels of both groups of patients were significantly lower than those before treatment while NO, SOD, GSH-Px and T-AOC levels were significantly higher than those before treatment; serum NTproBNP, Copeptin, Ang-II, ALD, ET-1, vWF, sST2, NO, 8-iso-PGF2a, MDA, SOD, GSH-Px and T-AOC levels of sequential group 3 d after treatment were not significantly different from those of control group; serum NT-proBNP, Copeptin, Ang-II, ALDET-1, vWF, sST2, 8-iso- PGF2a and MDA levels of sequential group 7 d after treatment were significantly lower than those of control group while NO, SOD, GSH-Px and T-AOC levels were significantly higher than those of control group. Conclusion: Sequential mechanical ventilation for cor pulmonale can improve the cardiac function and reduce the degree of endothelial injury and oxidative stress response.

  2. Acute haemodynamic effects of nifedipine at rest and during maximal exercise in patients with chronic cor pulmonale.

    Science.gov (United States)

    Singh, H; Ebejer, M J; Higgins, D A; Henderson, A H; Campbell, I A

    1985-01-01

    The pulmonary hypertension of cor pulmonale can be reversed by sustained correction of hypoxia but continuous oxygen treatment poses problems in clinical practice. Alternative methods of relieving pulmonary vasoconstriction have therefore been explored. Eight patients with chronic cor pulmonale (five of them men) were studied to measure the haemodynamic effects of the calcium antagonist nifedipine, both at rest and on maximal, symptom limited exercise. The mean duration of exercise was unchanged by nifedipine (7.8 (SD 3.3) compared with 7.3(3.1) min). Cardiac output rose from 5.2(1.5) l min-1 to 8.6(3.3) 1 min-1 on exercise. Nifedipine increased resting cardiac output by 26%, but did not influence maximal exercise output. It did not significantly alter resting mean pulmonary artery pressure but reduced the level during exercise from 67(15) to 52(11) mm Hg. Nifedipine lowered resting pulmonary vascular resistance (PVR) by 32% and exercise PVR by 28%. It reduced supine mean systemic arterial pressure by 17%, standing pressure by 22%, and pressure at the maximal exercise level by 20%. Nifedipine lowered supine systemic vascular resistance (SVR) by 35%, standing SVR by 28%, and exercise SVR by 20%. Haemodynamic changes were achieved without adverse symptoms, alteration in arterial PO2, or impairment of calculated oxygen delivery. Nifedipine therefore reduced both pulmonary and systemic vasomotor tone at rest and during exercise. It did not alter exercise tolerance, which is probably limited by underlying respiratory disease. It seems possible therefore that nifedipine could delay the development of cor pulmonale, although this hypothesis remains to be tested. PMID:4095671

  3. Shenmai injection as an adjuvant treatment for chronic cor pulmonale heart failure: a systematic review and meta-analysis of randomized controlled trials.

    Science.gov (United States)

    Shi, Liwei; Xie, Yanming; Liao, Xing; Chai, Yan; Luo, Yanhua

    2015-11-24

    Shenmai injection (SM), as a traditional Chinese medicine injection, is widely used for chronic cor pulmonale heart failure in mainland China. It is essential to systematically assess the efficacy and safety of SM as an adjuvant treatment for chronic cor pulmonale heart failure. Eight English and Chinese electronic databases were searched, from inception to December 2014, to identify randomized controlled trials (RCTs) of SM for chronic cor pulmonale heart failure. The Cochrane Risk of Bias tool was used to evaluate the methodological quality of eligible studies. Meta-analysis was performed by Review Manager 5.2. Twenty-seven RCTs with 2045 participants were identified. The methodological quality of the included studies was generally low. Only one trial reported data on death. None of the included trials reported quality of life. The meta-analysis indicated that compared to conventional treatment, the combination of SM and conventional treatment was more effective in terms of the New York Heart Association classification (RR, 1.26; 95% CI, 1.20-1.32; P cor pulmonale heart failure. However, due to the generally low methodological quality and small sample size, this review didn't find evidence to support routine use of SM as an adjuvant treatment for chronic cor pulmonale heart failure.

  4. Identification of genes from the ICE-CBF-COR pathway under cold stress inAegilops-Triticumcomposite group and the evolution analysis with those fromTriticeae.

    Science.gov (United States)

    Jin, Ya'nan; Zhai, Shanshan; Wang, Wenjia; Ding, Xihan; Guo, Zhifu; Bai, Liping; Wang, Shu

    2018-03-01

    Adverse environmental conditions limit various aspects of plant growth, productivity, and ecological distribution. To get more insights into the signaling pathways under low temperature, we identified 10 C-repeat binding factors ( CBFs ), 9 inducer of CBF expression ( ICEs ) and 10 cold-responsive ( CORs ) genes from Aegilops - Triticum composite group under cold stress. Conserved amino acids analysis revealed that all CBF, ICE, COR contained specific and typical functional domains. Phylogenetic analysis of CBF proteins from Triticeae showed that these CBF homologs were divided into 11 groups. CBFs from Triticum were found in every group, which shows that these CBFs generated prior to the divergence of the subfamilies of Triticeae . The evolutionary relationship among the ICE and COR proteins in Poaceae were divided into four groups with high multispecies specificity, respectively. Moreover, expression analysis revealed that mRNA accumulation was altered by cold treatment and the genes of three types involved in the ICE-CBF-COR signaling pathway were induced by cold stress. Together, the results make CBF , ICE , COR genes family in Triticeae more abundant, and provide a starting point for future studies on transcriptional regulatory network for improvement of chilling tolerance in crop.

  5. Influência da clorhexidina como inibidor das metaloproteinases na alteração da cor das resinas compostas

    OpenAIRE

    Chibeles, Inês Pereira

    2014-01-01

    Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz Objetivo: Verificar in vitro se a clorhexidina, como inibidor das metaloproteinases, provoca alteração de cor numa resina composta. Materiais e métodos: Vinte dentes terceiros molares hígidos foram distribuídos aleatoriamente em quatro grupos de cinco dentes. Cada grupo foi restaurado com a resina composta Filtek Z100 e tratado previamente com um protocolo de sistema adesivo formando os seg...

  6. A fatal case of cor pulmonale with undetected chronic hypoventilation in an infant with a known congenital myopathy.

    Science.gov (United States)

    Holst, John M; Willis, Mary J

    2012-01-01

    The authors of this paper wish to present a case of fatal cor pulmonale with right ventricular hypertrophy complicated by a congenital myopathy. It is our intention to demonstrate the importance of vigilant clinical assessment of children with a congenital myopathy, regardless of the exact etiology of their disease, or family history of disease severity. This case highlights the risk for fatal complications if hypoventilation and respiratory insufficiency go unrecognized in myopathic children. Consequently, we recommend respiratory and cardiac monitoring surveillance as well as appropriate referral to specialists in the management of such children.

  7. Influence of blood viscosity on circulatory parameters determined by first-pass radionuclide angiocardiography in cor pulmonale

    Energy Technology Data Exchange (ETDEWEB)

    Zambo, K. [Dept. of Nuclear Medicine, Pecs (Hungary); Toth, K. [Dept. of Medicine, Div. of Cardiology Univ. Medical School, Pecs (Hungary)

    1993-12-01

    First-pass radionuclide angiocardiography (FPRNA) with {sup 99m}Tc-albumin was performed in 19 patients with cor pulmonale. Pulmonary circulation time (PCT), mean transit time (MTT), pulmonary stagnation index (PSI) were calculated from the time-activity curves for the estimation of cardiopulmonary circulation. Whole blood viscosity (WBV), plasma viscosity (PV) and hematocrit (HTC) were also measured on the same day. Significant prolongation of all parameters was observed (WBW: 5,04{+-}1.19 mPAS; PV: 1,36{+-}0,17 mPAS; HTC: 47,6{+-}2,37%; PCT: 7,10{+-}2,15 s; MTT: 9,33{+-}4,11 s; PSI: 1,30{+-}0,37) in patients with cor pulmonale. Significant positive correlations were found between PCT and WBV (r=0,552; 0,001Cor pulmonale durchgefuehrt. Pulmonale Zirkulationszeit (PCT), `mean transit` Zeit (MTT), pulmonaler Rest Index (PSI) wurden ermittelt aus den Zeit-Aktivitaetskurven zur Einschaetzung des kardiopulmonalen Durchflusses. Vollblut-Viskositaet (WBV), Plasma-Viskositaet (PV) und Haematokrit (HTC) wurden am selben Tage gemessen. Bezeichnend fuer Patienten mit Cor pulmonale war eine typische Vergroesserung aller Parameter (WBV: 5,04{+-}1,19 mPAS; PV: 1,36{+-}0,17 mPAS; HTC: 47,6{+-}2,37%; PCT: 7,10{+-}2,15 s; MTT: 9,33{+-}4,11 s; PSI: 1,30{+-}0,37). Verwertbare Korrelationen wurden zwischen PCT und WBV (r=0,552; 0,001

  8. Las traducciones latinas del Corán, arma antislámica en la cristiandad medieval

    OpenAIRE

    Martínez Gázquez, José

    2005-01-01

    La Europa latina cristiana encontró en las traducciones latinas del Corán en la Edad Media un instrumento extraordinario para el conocimiento directo del Islam y un arma poderosa desde el punto de vista intelectual y religioso para la lucha contra los musulmanes The Christian Latin Europe found in the Middle Age an extraordinary instrument for the direct knowledge of the Islam and a powerful weapon from the intellectual and religious point of view for the struggle against the Muslims

  9. Cor pulmonale parvus” in chronic obstructive pulmonary disease (COPD) and emphysema. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study

    Science.gov (United States)

    Kawut, Steven M.; Poor, Hooman D.; Parikh, Megha A.; Hueper, Katja; Smith, Benjamin M.; Bluemke, David A.; Lima, Joao A.; Prince, Martin R.; Hoffman, Eric A.; Austin, John H. M.; Vogel-Claussen, Jens; Barr, R. Graham

    2015-01-01

    Background The classic cardiovascular complication of chronic obstructive pulmonary disease (COPD) is cor pulmonale, or enlargement of the right ventricle (RV). Most studies of cor pulmonale were conducted decades ago. Objective We aimed to examine RV changes in contemporary COPD and emphysema using cardiac magnetic resonance imaging (MRI). Methods We performed a case-control study nested predominantly in two general population studies of 310 participants with COPD and controls ages 50–79 years with ≥ 10 pack-years of smoking and who were free of clinical cardiovascular disease. RV volumes and mass were assessed using MRI. COPD and COPD severity were defined by standard spirometric criteria. Percent emphysema was defined as percent of lung regions cor pulmonale parvus”) and this reduction is related to greater percent emphysema on computed tomography. PMID:25440095

  10. A cor na obra de Donald Judd: interação entre matéria e luz

    Directory of Open Access Journals (Sweden)

    Paloma Carvalho

    2009-06-01

    Full Text Available Visamos explicitar como a luz, que incide e se propaga sobre as superfícies internas e externas das peças de Donald Judd, foi concebida pelo artista como parte constitutiva de sua estrutura física. A cor torna-se sinônimo da superfície material nas peças de Judd: ela é substantiva, inerente, não aplicada, e sem intenções metafóricas. Acompanhamos a tendência crítica recente de encontrar um conceito inovador de cor na obra de Donald Judd, que até pouco tempo atrás era tomada como a representante máxima de um minimalismo ortodoxo, distante de todo e qualquer apelo sensível.We try to make visible how the light that touches and propagates over Donald Judd´s pieces-its internal and external surfaces-was conceived by the artist in the same way as the physical structure of these. In Donald Judd's work, color turns into a synonym of material surface. It's inherent, substantive, non-applied and without metaphorical meanings. We are following the recent critical tendency that sees a new concept of color in Donald Judd's work that until some years ago was taken as an orthodox minimalist leader, far away from any appeal to the senses.

  11. Sinéreses cromossômicas: projeto de complementaridade semiósica entre som e cor

    Directory of Open Access Journals (Sweden)

    Eufrásio Prates

    2008-11-01

    Full Text Available O trabalho de Basbaum transita, transdisciplinarmente, pelos campos da neurologia cognitiva, arte, fí­sica, matemática, tecnologia, misticismo e teosofia, trazidos à baila para compor a teia da sinestesia ontológica do cromo-som, complexo indissociável e simultâneo de som e cor, como busca de interconexões originárias entre som e cor a partir da esfera da primeiridade peirciana, da constituição mesma do fenômeno sinestésico. Palavras-chave Sinestesia, primeiridade. Abstract The work of Basbaum as a research on the originary interconnections between sound and color based upon the Peircian firstness sphere concern, the constitution of the synesthesic phenomenon itself , goes transdisciplinarly through the fields of cognitive neurology, arts, physics, mathematics, technology, mysticism and theosophy, all of them with regard to the weaving of the ontological; synesthesia of the chromosound, an indissociable and simultaneous complex ofsound and color. Keywords Synesthesic phenomenon, Peircian firstness.

  12. Plexos coróides: estudo histopatológico em diferentes faixas etárias

    Directory of Open Access Journals (Sweden)

    Deise Regina Maffazzoni

    1986-12-01

    Full Text Available Os autores estudaram 146 casos de plexos coróides provenientes de autópsias realizadas no Departamento de Patologia da FFFCMPA, no período de janeiro de 1983 a outubro de 1984, com a finalidade de analisar as alterações histo-patológicas nas diferentes fases da vida. As idades dos pacientes estudados oscilaram de 26 semanas de vida intra-uterina a 87 anos. O estudo abrange 6 fetos, 26 recém-nascidos, 34 casos até um ano de idade, 4 de um a dois anos, 14 de 2 a 10 anos, 3 de 10 a 20 anos, 7 entre 20 a 30 anos, 14 de 30 a 40 anos, 23 de 40 a 60 anos, 12 de 60 a 80 anos e, três acima de 80 anos. A análise dos casos demonstrou diferenças quanto ao aspecto histopatológico dos plexos coróides, que variaram de células epiteliais vacuolizadas, presença de material eosinofílico no interstício - nos primeiros anos de vida - a calcificações restritas ao glomus e psamomas ou calcificações grosseiras, cuja intensidade acentuou-se com o aumento da faixa etária.

  13. DIASTOLIC DYSFUNCTION OF THE LEFT VENTRICLE IN THE PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND COR PULMONALE ECHO DOPPLER EVALUATION

    Directory of Open Access Journals (Sweden)

    Milan Radovic

    2006-01-01

    Full Text Available Cor pulmonale is a serious and long-term disease. The most imoportant etiologic factor is COPD. Patients with COPD and the right ventricle (RV hypertrophy, besides diastolic dysfunction of RV, had disturbances in diastolic characteristics of the left ventricle (LV, which was the result of hypertrophy of the left ventricle and the common septum. The aim of the study was to investigate diastolic function of the LV in two groups of COPD patients with or without cor pulmonale by using the Doppler ultrasound echocardiography. In the third group of patients with severe airway obstruction and respiratory failure, we found changed parameters of an early and late diastolic charging with presentation of the refilling model of extended relaxastion. We want to show that in patients with COPD, besides the RV hyperthrophy, there is the LV hyperthrophy, which confirms the fact about functional and anatomical relation of the RV and LV. We also showed that the left atrial hyperthrophy occurs due to the extended LV relaxation. An early and timely finding of the LV diastolic dysfunction in COPD patients could be significant in clinical practice, since it may be impaired during the disease, which leads to pulmonary congestion. Therefore, the early diagnosis and treatment of the LV diastolic dysfunction is essential for COPD patients.

  14. Administration of the cyclic peptide COR-1 in humans (phase I study): ex vivo measurements of anti-β1-adrenergic receptor antibody neutralization and of immune parameters.

    Science.gov (United States)

    Münch, Götz; Boivin-Jahns, Valerie; Holthoff, Hans-Peter; Adler, Kristin; Lappo, Mariola; Truöl, Stephan; Degen, Heidrun; Steiger, Nina; Lohse, Martin J; Jahns, Roland; Ungerer, Martin

    2012-11-01

    A novel concept for the treatment of heart failure is the neutralization of antibodies against the β(1)-adrenergic receptor (anti-β(1)AR-ab). In a rat model of autoimmune cardiomyopathy, the cyclic peptide COR-1 (given i.v. once monthly) neutralized anti-β(1)AR-abs and prevented anti-β(1)AR-ab-induced myocardial damage, and completely reverted cardiac dysfunction over 3-6 months. A clinical phase I trial was designed as a single-blinded, placebo-controlled study. Fifty human volunteers received COR-1 or matching placebo as a single i.v. administration with ascending doses (10-240 mg). Primary endpoints were safety and tolerability, while the pharmacokinetic profile of COR-1 was assessed as a secondary endpoint. All five investigated dose groups were well tolerated; no drug-related side effects occurred. Pharmacokinetics revealed a favourable profile with an almost complete plasma clearance within 60 min after administration. Pharmacodynamic investigation showed dose-dependent efficacy with almost complete scavenging of pathological anti-β(1)AR-abs ex vivo at the two highest doses. No anti-COR-1 autoantibodies occurred. No other effects on the immune system (such as an increase of crucial cytokines) were observed up to 43 days after drug administration, nor upon incubation of anti-β(1)AR-ab-positive patient blood samples with COR-1 ex vivo. COR-1 was shown to be safe after i.v. administration in vivo; no relevant side effects occurred. Efficacy was estimated from ex vivo investigation of the potency to neutralize specific anti-β(1)-AR-abs. NCT 01043146, Eudra CT 2008-007745-31.

  15. Comparison of strength, consistency, and speed of COR-KNOT versus manually hand-tied knots in an ex vivo minimally invasive model.

    Science.gov (United States)

    Lee, Candice Y; Sauer, Jude S; Gorea, Heather R; Martellaro, Angelo J; Knight, Peter A

    2014-01-01

    This study compared the strength, consistency, and speed of prosthetic attachment sutures secured with automated fasteners with those of manual knots using an ex vivo porcine mitral valve annuloplasty model. A novel miniature pressure transducer system was developed to quantify pressures between sutured prosthetic rings and underlying cardiac tissue. Sixteen mitral annuloplasty rings were sewn into ex vivo pig hearts. Eight rings were secured with the COR-KNOT device; and eight rings, with hand-tied knots using a knot pusher. A cardiac surgeon and a surgery resident each completed four manually tied rings and four COR-KNOT rings via a thoracotomy trainer. The total time to knot and cut each ring's sutures was recorded. Suture attachment pressures were measured within (intrasuture) and between (extrasuture) each suture loop using a 0.5 × 2.0-mm microtransducer probe system. The suture holding pressures for the COR-KNOT fasteners were significantly greater than for the manually tied knots (median, 1008.9 vs 415.8 mm Hg, P COR-KNOT fasteners than for the hand-tied knots (SD, 401.6 vs 499.3 mm Hg, P = 0.04). Significant time savings occurred with the use of the COR-KNOT compared with manual tying (12.4 vs 71.1 seconds per knot, P = 0.001). The novel microtransducer technology provided an innovative means of evaluating cardiac prosthetic anchoring sutures. In this model, mitral annuloplasty ring sutures secured with the COR-KNOT device were stronger, more consistent, and faster than with manually tied knots.

  16. Young infants with atopic dermatitis can display sensitization to Cor a 9, an 11S legumin-like seed-storage protein from hazelnut (Corylus avellana).

    Science.gov (United States)

    Verweij, Marjoke M; Hagendorens, Margo M; De Knop, Kathleen J; Bridts, Chris H; De Clerck, Luc S; Stevens, Wim J; Ebo, Didier G

    2011-03-01

    Allergy to hazelnut (Corylus avellana) can be severe and occur at young age. Atopic dermatitis (AD) can involve sensitization to various foods. The objective is to investigate the pattern of hazelnut sensitization in infants with AD. Sera of 34 infants all under 1 year of age and suffering from AD were selected according to prior specific IgE results. Twenty-nine infants were sensitized to traditional food allergens, five were not. From the 29 infants with a sensitization to at least one food allergen, 20 demonstrated IgE reactivity to hazelnut. All sera were analyzed with the allergen microarray immunoassay (ImmunoCAP ISAC). Twelve (60%) of the children with IgE reactivity to hazelnut demonstrated sensitization to Cor a 9, the 11S legumin-like seed-storage protein from hazelnut. In these infants, no sensitization to Cor a 1, the homologue of the major birch pollen allergen Bet v 1 (Betula verrucosa), or the lipid transfer protein (Cor a 8) from hazelnut was demonstrable. Half of the children sensitized to Cor a 9 demonstrated IgE reactivity to its homologue in peanut (Arachis hypogaea; Ara h 3) from which five were also sensitized to Gly m 6 from soy (Glycine max). None of the infants with AD without IgE reactivity to hazelnut demonstrated sensitization to Cor a 1, 8, or 9. In conclusion, young infants with atopic dermatitis sensitized to hazelnut can already display IgE reactivity to Cor a 9, a potentially dangerous hazelnut component. The mechanism(s) of this early sensitization and its clinical significance remain elusive. © 2010 John Wiley & Sons A/S.

  17. Biomassa de Rubrivivax gelatinosus na criação de frangos de corte: desempenho animal e cor dos produtos

    Directory of Open Access Journals (Sweden)

    S.V. Avanço

    2014-12-01

    Full Text Available A bactéria Rubrivivax gelatinosus tem sido utilizada experimentalmente no tratamento despoluente de efluentes industriais de abatedouros de aves e peixes, originando uma biomassa contendo pigmentos carotenoides, substâncias que possuem a capacidade de conferir cor aos alimentos e proteger contra reações oxidativas. Este trabalho teve por objetivo verificar o efeito da biomassa de R. gelatinosus adicionada à alimentação de frangos de corte sobre o desempenho animal e a cor de carne e pele. Duzentos pintos machos Cobb 500 foram distribuídos aleatoriamente em 20 boxes para receber, do 36º ao 45º dia de criação, quatro tratamentos com diferentes quantidades de biomassa na ração (T1 [controle] - 0g/kg; T2 - 1g/kg; T3 - 2g/kg; T4 - 3g/kg, em cinco repetições. As pesagens de aves e rações para a análise de desempenho foram feitas no início da criação e ao fim de cada período de crescimento. Ao final do experimento (45 dias, 20 aves de cada tratamento foram abatidas para a determinação da cor objetiva (L - luminosidade, C - saturação, h - tom em pele e carne de peito e coxa. Os resultados obtidos foram submetidos à ANOVA, teste t para a comparação múltipla de médias e análise de regressão com nível de significância de 5%. O ganho de peso e o consumo das aves não diferiram estatisticamente entre si (P>0,05, enquanto o índice de conversão alimentar foi superior para o T1. A luminosidade da carne e da pele aumentou significativamente nos tratamentos que receberam a biomassa. O tom da cor em carne e pele aumentou em direção ao amarelo até a concentração de 2g de biomassa por kg de ração, ao passo que, na concentração de 3g/kg, o aumento foi em direção à tonalidade vermelha. Somente na carne da coxa a saturação da cor sofreu influência da presença da biomassa na dieta. Concluiu-se que, até a proporção de 3g/kg, a biomassa não prejudicou o desempenho e foi eficiente em pigmentar a pele e a carne de

  18. ESTUDO DA ALTERAÇÃO DA COR E DEGRADAÇÃO DA CLOROFILA DURANTE ARMAZENAGEM DE ERVA-MATE TIPO CHIMARRÃO

    OpenAIRE

    Gisela Cabral Malheiros

    2007-01-01

    A Ilex paraguariensis A. St.-Hill., conhecida popularmente como erva-mate, é uma espécie nativa da região subtropical da América do Sul, a qual é matéria-prima para o produto ervamate, utilizado principalmente no preparo da bebida chimarrão. Dentre os atributos sensoriais da erva-mate tipo chimarrão, a cor constitui o primeiro critério utilizado pelo consumidor para sua aceitabilidade. A cor verde da erva-mate deve-se à presença de clorofila. Ocorrem perdas expressivas de clorofila no proc...

  19. Compte rendu de la mission effectuée en Corée du 22 novembre au 6 décembre 1980

    OpenAIRE

    Perez, Rene

    1980-01-01

    Sur invitation de la Fishery Research and Development Agency, le responsable du laboratoire d'Algologie Appliquée de l'Institut Scientifique et Technique des Pêches Maritimes a effectué une mission d'études en Corée du sud du 23 novembre au 6 décembre 1980. Le but de cette mission était de s'informer sur les techniques de culture intensive d'algues à vocation alimentaire et sur les modes de conditionnement, ainsi que de définir les intentions de la Corée en ce qui concerne l'utilisation des a...

  20. Efeito do armazenamento à baixa temperatura (-4 ºC) na cor e no teor de acidez da farinha de trigo

    OpenAIRE

    Ortolan,Fernanda; Hecktheuer,Luisa Helena; Miranda,Martha Zavariz de

    2010-01-01

    Durante o armazenamento de farinha de trigo, podem ocorrer mudanças bioquímicas que resultam em alterações nutricionais e tecnológicas, sendo que em baixa temperatura estas mudanças ocorrem mais lentamente. Entre as alterações, pode-se citar o aumento da acidez, a redução do pH e as modificações na sua cor. O presente trabalho teve por objetivo avaliar os efeitos do armazenamento à baixa temperatura (-4 ºC) na cor e na acidez da farinha de trigo durante seis meses e correlacionar os resultado...

  1. Case note: Hof Amsterdam (OK) (rolnummer 200.161.880/01 OK: Oprichting COR en indiening adviesaanvraag over sluiting één van de twee vestigingen op dag na oprichting, Besluit niet kennelijk onredelijk)

    NARCIS (Netherlands)

    Zaal, I.

    2015-01-01

    Het bedrijf Tjoapack heeft twee productielocaties: één in Emmen en één in Etten-Leur. Bij beide vestigingen is een ondernemingsraad ingesteld. Op voorstel van de ondernemer is op 28 oktober 2014 een COR geïnstalleerd. In de COR hebben vijf OR-leden zitting genomen: twee uit Emmen en drie uit

  2. Títulos e temas de 1 Cor 6,12-20 na unidade dos capítulos 5-7 = Titles and themes of 1 cor 6.12 -20 in theunity of the chapters 5-7

    Directory of Open Access Journals (Sweden)

    Oliveira, Flávio Martinez de

    2011-01-01

    Full Text Available Apresentam-se os títulos mais encontrados em 1 Cor 6,12-20 e na unidade dos capítulos 5-7. Expõem-se as propostas de articulação da perícope na unidade para propor, a partir de tais títulos e articulação, lendo a perícope, os temas aí considerados centrais. Tais temas são uma proposta de teologia bíblica para a perícope em seu contexto. Esta inspira a existência corporal cristã, tema da tese do autor, onde introduz e motiva a exegese lá exposta. Os temas escolhidos na perícope são porneia e corpo, pecado contra o corpo, corpo de Cristo e templo do Espírito Santo. São alternativas mutuamente excludentes o contato sexual com a prostituta, que implica a inteira existência corporal, e a pertença ao corpo de Cristo, no qual somos inseridos pelo Espírito Santo, do qual somos o templo. Identidade, estilo de vida e comportamento cristãos, teologia e ética são inseparáveis. Estas relações não eram compreendidas por muitos coríntios, os quais Paulo tem em vista. O corpo é central na perícope, perpassa toda a Primeira Carta aos Coríntios e relaciona-se ao próprio Evangelho de Paulo enquanto teologia do corpo. A porneia envolve a pessoa inteira de maneira estável e é um dos problemas que colocam a comunidade em conflito, ao lado de outras controvérsias conhecidas, e com esta relacionadas, como aquelas referentes aos carismas, à idolatria e à própria autoridade de Paulo

  3. Streptococcus pyogenes strains in Sao Paulo, Brazil: molecular characterization as a basis for StreptInCor coverage capacity analysis.

    Science.gov (United States)

    Freschi de Barros, Samar; De Amicis, Karine Marafigo; Alencar, Raquel; Smeesters, Pierre Robert; Trunkel, Ariel; Postól, Edilberto; Almeida Junior, João Nóbrega; Rossi, Flavia; Pignatari, Antonio Carlos Campos; Kalil, Jorge; Guilherme, Luiza

    2015-08-05

    Several human diseases are caused by Streptococcus pyogenes, ranging from common infections to autoimmunity. Characterization of the most prevalent strains worldwide is a useful tool for evaluating the coverage capacity of vaccines under development. In this study, a collection of S. pyogenes strains from Sao Paulo, Brazil, was analyzed to describe the diversity of strains and assess the vaccine coverage capacity of StreptInCor. Molecular epidemiology of S. pyogenes strains was performed by emm-genotyping the 229 isolates from different clinical sites, and PCR was used for superantigen profile analysis. The emm-pattern and tissue tropism for these M types were also predicted and compared based on the emm-cluster classification. The strains were fit into 12 different emm-clusters, revealing a diverse phylogenetic origin and, consequently, different mechanisms of infection and escape of the host immune system. Forty-eight emm-types were distinguished in 229 samples, and the 10 most frequently observed types accounted for 69 % of all isolates, indicating a diverse profile of circulating strains comparable to other countries under development. A similar proportion of E and A-C emm-patterns were observed, whereas pattern D was less frequent, indicating that the strains of this collection primarily had a tissue tropism for the throat. In silico analysis of the coverage capacity of StreptInCor, an M protein-conserved regionally based vaccine candidate developed by our group, had a range of 94.5 % to 59.7 %, with a mean of 71.0 % identity between the vaccine antigen and the predicted amino acid sequence of the emm-types included here. This is the first report of S. pyogenes strain characterization in Sao Paulo, one of the largest cities in the world; thus, the strain panel described here is a representative sample for vaccine coverage capacity analysis. Our results enabled evaluation of StreptInCor candidate vaccine coverage capacity against diverse M-types, indicating

  4. CORS Baade-Wesselink method in the Walraven photometric system: the period-radius and the period-luminosity relation of classical Cepheids

    NARCIS (Netherlands)

    Molinaro, R.; Ripepi, V.; Marconi, M.; Bono, G.; Lub, J.; Pedicelli, S.; Pel, J. W.

    We present a new derivation of the CORS Baade-Wesselink method in the Walraven photometric system. We solved the complete Baade-Wesselink equation by calibrating the surface brightness function with a recent grid of atmosphere models. The new approach was adopted to estimate the mean radii of a

  5. Uma nação para ser vista: desvelando o tempo e o espaço nacionais por meio da cor local na historiografia oitocentista

    Directory of Open Access Journals (Sweden)

    Eduardo Wright Cardoso

    Full Text Available RESUMO Se durante o século XIX a escrita da história adquire contornos mais precisos, é importante reconhecer o papel da cor local neste processo. O dispositivo assegura, por um lado, o caráter nacional das produções intelectuais e, por outro, oferece meios de legitimação e fidelidade para as narrativas do período. O escopo deste artigo é, pois, não somente reafirmar a associação entre a cor local e a nação, mas sugerir possibilidades de apreensão do dispositivo e, sobretudo, discorrer sobre as implicações e efeitos de seu emprego na elaboração da historiografia. Para isso, recorre-se tanto às prescrições relativas à cor local no contexto francês quanto aos textos da Revista do IHGB e de Varnhagen. Sugere-se, como hipótese, que a cor local é parte do vínculo que se estabelece entre tempo e espaço neste momento, além de possibilitar, devido à sua origem pictural, a criação de uma imagem da nação.

  6. A Longitudinal Evaluation of the Med-Cor Program's Efforts To Improve Minority Students' Postsecondary Educational Opportunities and Health Career Participation. Part B: Graduate Follow-Up Study.

    Science.gov (United States)

    Maddahian, Ebrahim; Barrera, Lourdes

    The Medical-Counseling, Organizing, and Recruiting (Med-COR) program is a project sponsored by the University of California School of Medicine and the Los Angeles Unified School District to provide career information and experience in the health professions for middle school and high school students. This study evaluated the impact of the Med-COR…

  7. Can the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) be used to accurately report clinic total reproductive potential (TRP)?

    Science.gov (United States)

    Stern, Judy E; Hickman, Timothy N; Kinzer, Donna; Penzias, Alan S; Ball, G David; Gibbons, William E

    2012-04-01

    To assess whether total reproductive potential (TRP), the chance of a live birth from each fresh cycle (fresh cycle plus frozen transfers), could be calculated from the national Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database and whether information not available in SART CORS resulted in significant changes to the TRP calculation. Retrospective study using SART CORS and clinic data. Three assisted reproductive technology clinics. Women undergoing ART. None. Two- and three-year TRPs for 2005 and 2006 were calculated according to patient age at cycle start by linking fresh to frozen cycles up to first live birth. Clinic records were used to adjust for (remove) frozen cycles that used more than one fresh cycle as a source of embryos and for any embryos donated to other patients or research or shipped to another facility before a live birth. TRP was higher than fresh per-cycle rates for most ages at all clinics, although accuracy was compromised when there were fewer than 20 cycles per category. Two- and 3-year TRPs differed in only 2 of 24 calculations. Adjusted TRPs differed less than three percentage points from unadjusted TRPs when volume was sufficient. Clinic TRP can be calculated from SART CORS. Data suggest that calculations of clinic TRP from the national dataset would be meaningful. Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  8. InsCor: um método simples e acurado para avaliação do risco em cirurgia cardíaca

    Directory of Open Access Journals (Sweden)

    Omar A. V. Mejía

    2013-03-01

    Full Text Available FUNDAMENTO: Escores de risco apresentam dificuldades para obter o mesmo desempenho em diferentes populações. OBJETIVO: Criar um modelo simples e acurado para avaliação do risco nos pacientes operados de doença coronariana e/ou valvar no Instituto do Coração da Universidade de São Paulo (InCor-HCFMUSP. MÉTODOS: Entre 2007 e 2009, 3.000 pacientes foram operados consecutivamente de doença coronariana e/ou valvar no InCor-HCFMUSP. Desse registro, dados de 2/3 dos pacientes foram utilizados para desenvolvimento do modelo (técnica de bootstrap e de 1/3 para validação interna do modelo. O desempenho do modelo (InsCor foi comparado aos complexos 2000 Bernstein-Parsonnet (2000BP e EuroSCORE (ES. RESULTADOS: Apenas 10 variáveis foram selecionadas: Idade > 70 anos; sexo feminino; cirurgia de revascularização coronariana + valva; infarto de miocárdio < 90 dias; reoperação; tratamento cirúrgico da valva aórtica; tratamento cirúrgico da valva tricúspide; creatinina < 2mg/dL; fração de ejeção < 30%; e eventos. O teste de Hosmer Lemeshow para o InsCor foi de 0,184, indicando uma excelente calibração. A área abaixo da curva ROC foi de 0,79 para o InsCor, 0,81 para o ES e 0,82 para o 2000BP, confirmando que os modelos são bons e similares na discriminação. CONCLUSÕES: O InsCor e o ES tiveram melhor desempenho que o 2000BP em todas as fases da validação; pórem o novo modelo, além de se identificar com os fatores de risco locais, é mais simples e objetivo para a predição de mortalidade nos pacientes operados de doença coronariana e/ou valvar no InCor-HCFMUSP.

  9. Risco para transtornos alimentares em escolares de Salvador, Bahia, e a dimensão raça/cor

    Directory of Open Access Journals (Sweden)

    Liliane de Jesus Bittencourt

    2013-10-01

    Full Text Available OBJETIVO: Estimar a existência de fatores de risco associados aos transtornos alimentares em escolares da cidade de Salvador, Bahia, por meio da dimensão étnico-racial como fator de heterogeneidade. MÉTODOS: Os participantes da pesquisa são escolares do sexo feminino, na faixa etária entre 15 e 30 anos, residentes na cidade de Salvador, no Estado da Bahia. Foram investigadas 626 estudantes, selecionadas em instituições públicas e privadas de ensino médio e universitário. Utilizaram-se o Eating Atittude Test-26, o Body Shape Questionnaire e o Beck Depression Inventory como instrumentos de identificação de risco para os transtornos alimentares. A classificação étnico-racial se deu por autodeclaração, de acordo com as categorias do Instituto Brasileiro de Geografia e Estatística. Foram realizadas análises descritivas, bivariadas (χ2 de Pearson e regressão logística multivariada para análise dos dados. RESULTADOS: As estudantes que se identificaram como amarelas ou indígenas têm 3,6 vezes mais chances de desenvolverem comportamentos alimentares desordenados e 4,8 vezes mais possibilidade de estarem insatisfeitas com sua imagem corporal. As pardas apresentam 2,5 vezes mais risco para essa insatisfação. A depressão é uma comorbidade que deve ser considerada, apesar de não estar associada significativamente à raça/cor. CONCLUSÃO: As mulheres não brancas em Salvador apresentam risco de desenvolver transtornos alimentares. Outros estudos que combinam métodos quantitativos e qualitativos podem permitir uma análise mais robusta quanto à relação entre transtornos alimentares e raça/cor e etnia.

  10. Raça/cor da pele e transtornos mentais no Brasil: uma revisão sistemática

    Directory of Open Access Journals (Sweden)

    Jenny Rose Smolen

    Full Text Available Resumo Transtornos mentais contribuem para uma grande carga de incapacidade. Esta revisão sistemática tem como objetivo resumir a literatura sobre raça/cor da pele e transtornos mentais no Brasil. PubMed e Lilacs foram pesquisados com o uso de descritores sobre transtornos mentais (depressão, ansiedade, etc. e raça/cor da pele. Estudos sobre grupos não populacionais, que não analisaram raça/cor da pele, ou em que o transtorno mental não foi o objeto de estudo não foram incluídos. Depois da avaliação de qualidade, 14 estudos foram selecionados para inclusão. A tendência foi uma prevalência maior de transtornos mentais nas pessoas não brancas. Das seis análises multivariadas que acharam resultados estatisticamente significantes, cinco mostraram uma maior prevalência ou chance de transtornos mentais nas pessoas não brancas em comparação com pessoas brancas (medida de associação entre 1,18 e 1,85. Essa revisão contribuiu para identificar a tendência na literatura em relação à associação entre raça/cor da pele e transtornos mentais, mas há importantes dificuldades com relação à comparabilidade dos estudos, principalmente, em função das diferenças em relação aos transtornos mentais estudados, as formas de categorizar raça/cor da pele e nos instrumentos utilizados nos estudos analisados.

  11. Remoção de cor de efluentes têxteis com cogumelos Agaricus bispora - doi: 10.4025/actascitechnol.v32i3.6339

    Directory of Open Access Journals (Sweden)

    Renata Lopes Landeira Silva

    2010-11-01

    Full Text Available O emprego direto de cogumelos Agaricus bispora foi avaliado para a remoção de cor de uma mistura sintética de corantes reativos. Avaliou-se o efeito da granulometria das partículas (cubos de 0,5 ou 1,0 cm e cogumelos moídos, da massa de cogumelos (10, 20, 40, 60 ou 80 g em 250 mL de solução e de diferentes formas de tratamento do cogumelo sobre a remoção de cor de uma solução sintética dos corantes Reactive Yellow 37, Reactive Black 5 e Reactive Red na concentração de 13,3 mg L-1 cada corante. Os melhores resultados foram obtidos para maiores áreas superficiais de contato do cogumelo (cogumelo moído com o efluente colorido e sob aeração contínua. A adição de acetona durante o processo de moagem, seguido de congelamento, contribuiu para o aumento da remoção de cor, obtendo-se os melhores resultados: 73% após 6h, com 20 g de biocatalisador 250 mL-1 de efluente. A utilização de diferentes lotes e marcas de cogumelo levou à obtenção de diferentes atividades enzimáticas, mas percentuais similares de remoção de cor, indicando que a remoção de cor não possui relação direta com a atividade enzimática.

  12. Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study.

    Science.gov (United States)

    Miniati, Massimo; Monti, Simonetta; Basta, Giuseppina; Cocci, Franca; Fornai, Edo; Bottai, Matteo

    2011-03-30

    The receptor for advanced glycation end products (RAGE) is a multiligand signal transduction receptor that can initiate and perpetuate inflammation. Its soluble isoform (sRAGE) acts as a decoy receptor for RAGE ligands, and is thought to afford protection against inflammation. With the present study, we aimed at determining whether circulating sRAGE is correlated with emphysema and chronic cor pulmonale in chronic obstructive pulmonary disease (COPD). In 200 COPD patients and 201 age- and sex-matched controls, we measured lung function by spirometry, and sRAGE by ELISA method. We also measured the plasma levels of two RAGE ligands, N-epsilon-carboxymethyl lysine and S100A12, by ELISA method. In the COPD patients, we assessed the prevalence and severity of emphysema by computed tomography (CT), and the prevalence of chronic cor pulmonale by echocardiography. Multiple quantile regression was used to assess the effects of emphysema, chronic cor pulmonale, smoking history, and comorbid conditions on the three quartiles of sRAGE. sRAGE was significantly lower (p = 0.007) in COPD patients (median 652 pg/mL, interquartile range 484 to 1076 pg/mL) than in controls (median 869 pg/mL, interquartile range 601 to 1240 pg/mL), and was correlated with the severity of emphysema (p cor pulmonale than in those without (p = 0.002). Such difference remained statistically significant after adjusting for smoking history, comorbidities, and emphysema severity. There was no significant difference in the plasma levels of the two RAGE ligands between cases and controls. sRAGE is significantly lower in patients with COPD than in age- and sex-matched individuals without airflow obstruction. Emphysema and chronic cor pulmonale are independent predictors of reduced sRAGE in COPD.

  13. Comparison of color indexes for tomato ripening Comparação dos índices de cor para maturação do tomate

    Directory of Open Access Journals (Sweden)

    Andrés F. López Camelo

    2004-09-01

    Full Text Available Color in tomato is the most important external characteristic to assess ripeness and postharvest life, and is a major factor in the consumer's purchase decision. Degree of ripening is usually estimated by color charts. Colorimeters, on the other hand, express colors in numerical terms along the L*, a* and b* axes (from white to black, green to red and blue to yellow, respectively within the CIELAB color sphere which are usually mathematically combined to calculate the color indexes. Color indexes and their relationship to the visual color classification of tomato fruits vine ripened were compared. L*, a* and b* data (175 observations from eleven cultivars from visually classified fruits at harvest in six ripening stages according to the USDA were used to calculate hue, chroma, color index, color difference with pure red, a*/b* and (a*/b*². ANOVA analysis were performed and means compared by Duncan's MRT. Color changes throughout tomato ripening were the result of significant changes in the values of L*, a* and b*. Under the conditions of this study, hue, color index, color difference and a*/b* expressed essentially the same, and the color categories were significantly different in terms of human perception, with hue showing higher range of values. Chroma was not a good parameter to express tomato ripeness, but could be used as a good indicator of consumer acceptance when tomatoes are fully ripened. The (a*/b*² relationship had the same limitations as chroma. For vine ripened fruits, hue, color index, color difference and a*/b* could be used as objective ripening indexes. It would be interesting to find out what the best index would be if ripening took place under inadequate conditions of temperature and ilumination.A cor do tomate é a característica externa mais importante que permite determinar a maturação e estimar a vida pós-colheita, sendo por sua vez um fator importante na decisão de compra por parte do consumidor. O grau de matura

  14. Chorea: clinical correlates of 119 cases Coréia: análise clínica de 119 casos

    Directory of Open Access Journals (Sweden)

    Maria Fernanda Mendes

    1996-09-01

    Full Text Available Chorea is a clinical syndrome characterized by abnormal involuntary arrhythmic movements, randomly distributed in time, affecting mainly the distal parts of the limbs. There are many diseases associated with chorea but the distribution of the etiologies vary too much in different parts of the world. We intended to study the etiologies of chorea in a Movement Disorders Unit of a university hospital-based outpatient clinic in Brazil. We studied the records of 119 patients with chorea based in the diagnostic criteria of the World Federation of Neurology. Sydenham's chorea (SC was the most frequent cause of chorea (51.3% of our sample. Other common causes were Huntington's chorea (18.5% and chorea post-stroke (9.2%. SC is not commonly seen in developed countries nowadays but is not rare in Brazil. SC patients generally have the clinical manifestation of it in the first 20 years of age and girls are more affected than boys and this feature was observed in our sample. Based on our own experience and in the review of the literature we propose an etiological classification of chorea.Coréia é uma síndrome caracterizada por movimentos involuntários arrítmicos, rápidos, abruptos, não repetitivos no tempo e com distribuição variável, preferentemente distal. O número de entidades clínicas reconhecidamente associadas a movimentos coréicos tem se tornado cada vez maior com o passar do tempo. Propusemo-nos estudar a frequência e algumas características epidemiológicas das coréias atendidas em um ambulatório especializado em distúrbios do movimento. Foram estudados os prontuários de 119 pacientes com o diagnóstico sindrômico de coréia. O predomínio absoluto foi de coréia de Sydenham (CS com 51,3% do total da amostra. Outras causas frequentes foram doença de Huntington (DH presente em 18,5% e a coréia secundária a doença cerebrovascular em 9,2% dos pacientes. O sexo feminino predominou em todas as faixas etárias, mas principalmente

  15. Stucs et décors de la fin de l’Antiquité au Moyen Âge (Ve-XIIe siècle

    Directory of Open Access Journals (Sweden)

    Christian Sapin

    2007-08-01

    Full Text Available Stucs et décors de la fin de l’Antiquité au Moyen Âge (Ve-XIIe siècle, actes du colloque international tenu à Poitiers du 16 au 19 septembre 2004, Ch. Sapin (dir., Turnhout, Brepols, 2006 (Bibliothèque de l’Antiquité Tardive, 10.Le stuc, un art à part entièreLa connaissance du stuc comme matériau et processus de décor a longtemps été ignorée. En même temps que l’exposition consacrée au Stuc, visage oublié de l’art médiéval, montée par le Centre d’études médiévales (Bénédicte Bertholon-Pala...

  16. Stucs et décors de la fin de l’Antiquité au Moyen Âge (du Ve au XIIe siècle

    Directory of Open Access Journals (Sweden)

    Christian Sapin

    2004-02-01

    Full Text Available L’utilisation du stuc comme matériau de décor est encore très mal perçue en France. Plusieurs colloques sur la technique du stuc ou sa conservation ont eu lieu en Italie et en Allemagne, mais aucun n’a pris en compte sa dimension historique sur une longue durée, de l’Antiquité au Moyen Âge. L’étude des 2 500 fragments provenant du site de Vouneuil, à proximité de Poitiers, a permis la restitution d’un ensemble iconographique exceptionnel. série de douze arcades, ensemble de panneaux décorés, ...

  17. As Moléculas da Cor: Nas Máscaras da Viagem Filosófica (1783-1792) e Num Tecido Oriental (1880)

    OpenAIRE

    Carapito, Susana Takato Oliveira Manaia

    2014-01-01

    Neste trabalho foi efetuado o estudo da identificação das moléculas da cor em 3 objetos históricos: duas máscaras dos índios Yurupixuna e uma peça de seda e algodão de cor púrpura, pertencentes ao espólio da coleção etnográfica do Gabinete de Antropologia do Museu da Ciência da Universidade de Coimbra (GAMCUC). As duas máscaras etnográficas, provêm da Viagem Filosófica pelas Capitanias do Grão-Pará, Mato-grosso e Cuiabá, realizada por Alexandre Rodrigues Ferreira (ARF) em finai...

  18. An autopsy case of acute cor pulmonale and paradoxical systemic embolism due to tumour cell microemboli in a patient with breast cancer.

    Science.gov (United States)

    Uga, Sayuri; Ikeda, Shuntaro; Matsukage, Sho-ichi; Hamada, Mareomi

    2012-09-30

    A 62-year-old woman was admitted to our hospital because of severe respiratory distress. Diagnostic imaging studies suggested the existence of inexplicable cor pulmonale. Although we immediately sought the aetiology of her severe condition, she died suddenly on the fourth day after admission. Postmortem autopsy revealed tumour cell microemboli in the small pulmonary arteries. In addition, tumour cell embolisation identical to that in primary breast cancer cells was also observed in microvessels in systemic multiple organs, such as the liver, brain, kidneys, spleen, uterus, bone marrow and adrenal glands-with simultaneous findings of peripheral infarction. Systemic tumour cell embolism mediated through the patent foramen ovale superimposed on pulmonary tumour cell emboli (PTCE) is considered to be the mechanism underlying inexplicable cor pulmonale. The rapid aggravation of her condition terminated in death.

  19. Acute pulmonary embolism: prediction of cor pulmonale and short-term patient survival from assessment of cardiac dimensions in routine multidetector-row CT

    International Nuclear Information System (INIS)

    Engeike, C.; Rummeny, E.; Marten, K.

    2006-01-01

    Purpose: evaluation of the prognostic value of morphological cardiac parameters in patients with suspected and incidental acute pulmonary embolism (PE) using multidetector-row chest CT (MSCT). Materials and methods: 2335 consecutive MSCT scans were evaluated for the presence of PE. The arterial enhancement and analysability of pulmonary arteries and the heart were assessed as parameters of the scan quality. The diastolic right and left ventricular short axes (RV D , LV D ) and the interventricular septal deviation (ISD) were measured in all PE-positive patients and the echocardiography reports were reviewed. The clinical data assessment included cardio-respiratory and other co-morbidities, systemic anticoagulant therapy (ACT), and the 30-day outcome. Predictors of acute cor pulmonale and the short-term outcome were calculated by univariate and multivariate logistic regressions including odds ratios (OR) and ROC analyses using positive (PPV) and negative predictive values (NPV). Results: 90 patients with acute PE were included (36 with clinically suspected PE, 54 with incidental PE). 26 patients had cardio-respiratory co-morbidities. Four patients underwent systemic thrombolysis, 43 underwent anticoagulation in therapeutic doses, 19 underwent anticoagulation in prophylactic doses, and 24 patients did not undergo ACT. 15 of 41 patients had echocardiographic evidence of acute cor pulmonale. 8 patients died within 30 days. The RV D was the best independent predictor of acute cor pulmonale (p = 0,002, OR = 9.16, PPV = 0.68, NPV=1 at 4.49 cm cut off) and short-term outcome (p= 0,0005, OR = 2.82, PPV = 0.23, NPV = 0.98 at 4.75 cm cut off). The RV D /LV D ratio had a PPV of 0.85 for cor pulmonale. (orig.)

  20. Effectiveness of the SpineCor brace based on the new standardized criteria proposed by the scoliosis research society for adolescent idiopathic scoliosis.

    Science.gov (United States)

    Coillard, Christine; Vachon, Valerie; Circo, Alin B; Beauséjour, Marie; Rivard, Charles H

    2007-06-01

    The purpose of this prospective observational study was to evaluate the effectiveness of the Dynamic SpineCor brace for adolescent idiopathic scoliosis in accordance with the standardized criteria proposed by the Scoliosis Research Society Committee on Bracing and Nonoperative Management. They proposed these guidelines to make the comparison among studies more valid and reliable. From 1993 to 2006, 493 patients were treated using the SpineCor brace. Two hundred forty-nine patients met the criteria for inclusion, and 79 patients were still actively being treated. Overall, 170 patients have a definitive outcome. All girls were premenarchal or less than 1 year postmenarchal. Assessment of brace effectiveness included (1) percentage of patients who have 5 degrees or less curve progression, and percentage of patients who have 6 degrees or more progression; (2) percentage of patients who have been recommended/undergone surgery before skeletal maturity; (3) percentage of patients with curves exceeding 45 degrees at maturity (end of treatment); and (4) Two-year follow-up beyond maturity to determine the percentage of patients who subsequently underwent surgery. Successful treatment (correction, >5 degrees, or stabilization, +/-5 degrees) was achieved in 101 (59.4%) of the 170 patients from the time of the fitting of the SpineCor brace to the point in which it was discontinued. Thirty-nine immature patients (22.9%) required surgical fusion while receiving treatment. Two (1.2%) of 170 patients had curves exceeding 45 degrees at maturity. One mature patient (2.1%) required surgery within 2 years of follow-up beyond skeletal maturity. The conclusion drawn from these findings is that the SpineCor brace is effective for the treatment of adolescent idiopathic scoliosis. Moreover, positive outcomes are maintained after 2 years because 45 (95.7%) of 47 patients stabilized or corrected their end of bracing Cobb angle up to 2 years after bracing. Therapeutic study-investigating the

  1. A Novel Inflammation- and Nutrition-Based Prognostic System for Patients with Laryngeal Squamous Cell Carcinoma: Combination of Red Blood Cell Distribution Width and Body Mass Index (COR-BMI.

    Directory of Open Access Journals (Sweden)

    Yan Fu

    Full Text Available Laryngeal squamous cell carcinoma (LSCC is a head and neck cancer type. In this study, we introduced a novel inflammation- and nutrition-based prognostic system, referred to as COR-BMI (Combination of red blood cell distribution width and body mass index, for LSCC patients.A total of 807 LSCC patients (784 male and 23 female, 22-87 y of age who underwent surgery were enrolled in this retrospective cohort study. The patients were stratified by COR-BMI into three groups: COR-BMI (0 (RDW ≤ 13.1 and BMI ≥ 25; COR-BMI (1 (RDW ≤ 13.1 and BMI 13.1 and 18.5 ≤ BMI 13.1 and BMI < 18.5. Cox regression models were used to investigate the association between COR-BMI and cancer-specific survival (CSS rate among LSCC patients.The 5-y, 10-y, and 15-y CSS rates were 71.6%, 60.1%, and 55.4%, respectively. There were significant differences among the COR-BMI groups in age (< 60 versus ≥ 60 y; P = 0.005 and T stage (T1, T2, T3, or T4; P = 0.013. Based on the results, COR-BMI (1 versus 0: HR = 1.76; 95% CI = 0.98-3.15; 2 versus 0: HR = 2.91; 95% CI = 1.53-5.54, P = 0.001 was a significant independent predictor of CSS.COR-BMI is a novel inflammation- and nutrition-based prognostic system, which could predict long-term survival in LSCC patients who underwent surgery.

  2. The 3-D strain patterns in Turkey using geodetic velocity fields from the RTK-CORS (TR) network

    Science.gov (United States)

    Kutoglu, Hakan Senol; Toker, Mustafa; Mekik, Cetin

    2016-03-01

    This study presents our use of GPS data to obtain and quantify the full continuous strain tensor using a 3-D velocity field in Turkey. In this study, GPS velocities improve the estimation of short-term strain tensor fields for determining the seismic hazard of Turkey. The tensorial analysis presents different aspects of deformation, such as the normal and shear strains, including their directions, the compressional and extensional strains. This analysis is appropriate for the characterizing the state of the current seismic deformation. GPS velocity data from continuous measurements (2009-2012) to estimate deformations were processed using the GAMIT/GLOBK software. Using high-rate GPS data from permanent 146 GNSS stations (RTK-CORS-TR network), the strain distribution was determined and interpolated using a biharmonic spline technique. We show the strain field patterns within axial and plane form at several critical locations, and discuss these results within the context of the seismic and tectonic deformation of Turkey. We conclude that the knowledge of the crustal strain patterns provides important information on the location of the main faults and strain accumulation for the hazard assessment. The results show an agreement between the seismic and tectonic strains confirming that there are active crustal deformations in Turkey.

  3. Alteração da cor da madeira de teca por tratamento térmico

    Directory of Open Access Journals (Sweden)

    Juliana de Oliveira Lopes

    Full Text Available O objetivo deste estudo foi determinar o efeito do tratamento térmico na alteração da cor da madeira de teca (Tectona grandis L. f., proveniente de plantios de diferentes espaçamentos. Amostras de madeira de cerne e de alburno foram tratadas a 180 e 200ºC durante 2h30min. As análises colorimétricas foram realizadas com o auxílio do espectrofotômetro CM 2600d no sistema CIE L*a*b*. Após o tratamento, a madeira teve perda de luminosidade, tornado-se mais escura, o que se mostrou mais acentuado para o tratamento a 200ºC. As madeiras de cerne e alburno apresentaram comportamentos diferentes para as coordenadas a* e b*, dependendo do espaçamento, antes e após o tratamento. Ocorreu uma maior formação de pigmento vermelho e perda de pigmento amarelo nas madeiras de cerne e alburno tratadas a 200ºC.

  4. [The specific features of left cardiac cavity remodeling in patients with chronic obstructive pulmonary disease and chronic cor pulmonale].

    Science.gov (United States)

    Strutynskiĭ, A V; Bakaev, R G; Glazunov, A B; Banzeliuk, E N; Moshkova, N K; Reĭsner, A A; Shavurdina, S V; Vinogradova, D V

    2010-01-01

    To study left ventricular structural and functional changes in patients with chronic obstructive pulmonary disease (COPD) and chronic cor pulmonale (CCP) at different stages of a cardiac remodeling process. Echocardiography was used to examine 98 patients with COPD complicated by the development of CCP in a number of cases. The significant signs of CCP were absent in 19 patients; the signs of compensated and decompensated CCP in 41 and 38 patients, respectively. In the patients with COPD, the formation of CCP during remodeling of the heart involves its left cavities whose changes lie in the occurrence of left ventricular (LV) diastolic dysfunction, mainly of the restrictive type, in ventricular spherization, higher myocardial systolic tension, in tendencies towards increases in LV mass index, left atrial sizes, and in the indices reflecting LV systolic dysfunction. The LV diastolic dysfunction correlates with the degree of right ventricular hypertrophy and dilatation and the presence of complete right bundle-branch block. Progressive worsening of diagnostic filling of the left ventricle and its systolic function is an additional factor aggravating hemodynamic disorders in patients with COPD and CCP, which should be kept in mind on choosing an appropriate therapy for patients with CCP.

  5. Articulações entre gênero e raça/cor em situações de violência de gênero

    Directory of Open Access Journals (Sweden)

    Raquel da Silva Silveira

    2014-08-01

    Full Text Available Este artigo discute teoricamente as articulações entre gênero e raça/cor na temática da violência de gênero nas relações de intimidade. A fundamentação teórica é composta pelos estudos de Michel Foucault sobre as relações de poder, pelos estudos contemporâneos de gênero (Joan Scott, Heleith Saffioti, Karin Smigay e pelos estudos de raça/cor (Florestan Fernandes, Lilia Schwarcz. O trabalho de campo, envolvendo entrevistas e análise de andamento de processos judiciais, foi desenvolvido no Juizado de Violência Doméstica e Familiar contra a Mulher e na Delegacia da Mulher, em Porto Alegre, no período de maio de 2010 a outubro de 2011. Destaca-se como necessária a problematização sobre as formas como as questões de raça/cor se entrecruzam nos discursos sobre violência de gênero nas relações de intimidade, uma vez que a maneira como as vulnerabilidades são vividas pelas mulheres variam fortemente de acordo com suas experiências singulares de vida e com os marcadores sociais.

  6. Electrical impedance tomography-guided prone positioning in a patient with acute cor pulmonale associated with severe acute respiratory distress syndrome.

    Science.gov (United States)

    Kotani, Toru; Tanabe, Hitoshi; Yusa, Hiroaki; Saito, Satoshi; Yamazaki, Kenji; Ozaki, Makoto

    2016-02-01

    Electrical impedance tomography (EIT) is a noninvasive technique used to assess regional gas distribution in the lung. We experienced a patient with acute cor pulmonale during high positive-pressure ventilation for the treatment of severe acute respiratory distress syndrome. Prone positioning was beneficial for unloading the right ventricle for treatment of acute cor pulmonale. EIT played a role in detecting lung derecruitment at the patient's bedside. Impedance distribution in ventral, mid-ventral, mid-dorsal, and dorsal layers before and 20 min after the start of prone positioning was 9, 48, 44, and 0 %, and 10, 25, 48, and 16 %, respectively. Lung recruitment monitored by EIT paralleled the improvement of PaO2/FIO2 from 123 to 239 mmHg. Timing of termination of prone positioning and ventilator settings such as lowering positive end-expiration pressure was determined to maintain dorsal recruitment as seen by EIT. The patient was weaned from mechanical ventilation on day 32 and discharged on day 200. EIT assessed the effects of prone positioning with real-time dynamic imaging and guided less injurious mechanical ventilation in a patient with acute cor pulmonale with dorsal lung derecruitment.

  7. Éloge du décor : l’église Saint-Jean-Bosco à Paris, sanctuaire national du père des orphelins

    Directory of Open Access Journals (Sweden)

    Valérie Gaudard

    2009-11-01

    Full Text Available Architecte méconnu, D. Rotter élève en 1933 le sanctuaire national de l’ordre de Saint-Jean-Bosco, soixantième chantier du cardinal Verdier. Élément d’un projet plus vaste de bâtiments destinés à l’éducation des jeunes défavorisés, l’église en béton armé, à la silhouette proche de l’église du Raincy, frappe par l’originalité, la richesse et la bonne conservation de son décor. Bessac et Gaudin signent une partie du décor dû pour l’essentiel à Mauméjean Frères. Cet unicum parisien contient l’un des derniers décors figurés d’église avant leur disparition après-guerre.

  8. A cor da dor: iniquidades raciais na atenção pré-natal e ao parto no Brasil

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Leal

    Full Text Available Poucas pesquisas com foco nas influências da raça/cor no tocante à experiência de gestação e parto foram conduzidas no Brasil, sendo inédita a análise de abrangência nacional. Este estudo teve como objetivo avaliar as iniquidades na atenção pré-natal e parto de acordo com a raça/cor utilizando o método de pareamento baseado nos escores de propensão. Os dados são oriundos da pesquisa Nascer no Brasil: Pesquisa Nacional sobre Parto e Nascimento, um estudo de base populacional de abrangência nacional com entrevista e avaliação de prontuários de 23.894 mulheres em 2011/2012. Regressões logísticas simples foram utilizadas para estimar as razões de chance (OR e respectivos intervalos de 95% de confiança (IC95% da raça/cor associada aos desfechos analisados. Em comparação às brancas, puérperas de cor preta possuíram maior risco de terem um pré-natal inadequado (OR = 1,6; IC95%: 1,4-1,9, falta de vinculação à maternidade (OR = 1,2; IC95%: 1,1-1,4, ausência de acompanhante (OR = 1,7; IC95%: 1,4-2,0, peregrinação para o parto (OR = 1,3; IC95%: 1,2-1,5 e menos anestesia local para episiotomia (OR = 1,5 (IC95%: 1,1-2,1. Puérperas de cor parda também tiveram maior risco de terem um pré-natal inadequado (OR = 1,2; IC95%: 1,1-1,4 e ausência de acompanhante (OR = 1,4; IC95%: 1,3-1,6 quando comparadas às brancas. Foram identificadas disparidades raciais no processo de atenção à gestação e ao parto evidenciando um gradiente de pior para melhor cuidado entre mulheres pretas, pardas e brancas.

  9. Uso da cor da casca como indicador de qualidade do maracujá amarelo (Passiflora edulis Sims. f. flavicarpa Deg. destinado à industrialização

    Directory of Open Access Journals (Sweden)

    DE MARCHI Renata

    2000-01-01

    Full Text Available As características físico-químicas do maracujá amarelo em três estádios de cor de casca (1/3 amarelo, 2/3 amarelo e inteiro amarelo, em quatro épocas da safra/99 foram avaliadas, visando estabelecer o ponto de colheita de melhor qualidade da fruta para a industrialização. Foram determinados o tamanho dos frutos, a cor da casca e da polpa, o rendimento de extração da polpa, o teor de sólidos solúveis totais, o pH, a acidez total, o ratio e o teor de vitamina C. Foi empregado o delineamento experimental inteiramente casualizado, com 8 repetições, 5 frutos por parcela e 3 tratamentos. Os resultados mostraram que o rendimento de polpa não apresentou diferença significativa entre os tratamentos e entre as colheitas. Com relação à cor da polpa, houve diferença significativa entre os três estádios apenas na 1ª colheita. Os frutos de casca 1/3 amarela apresentaram teor de sólidos solúveis significativamente inferior aos demais apenas na 3ª e 4ª colheitas, mas o maior valor médio ocorreu na 4ª colheita. O teor de acidez total dos frutos de casca inteira amarela foi significativamente inferior àqueles das colheitas 2, 3 e 4. Os valores mais elevados de vitamina C foram obtidos na 1ª colheita e, os frutos de casca 1/3 amarela apresentaram teores significativamente inferiores nas colheitas 1 e 2. De maneira geral, os resultados indicaram que, embora tenham ocorrido algumas diferenças nas características físico-químicas dos frutos nos diferentes estádios de cor de casca, frutos colhidos em todos os estádios de cor de casca estudados apresentaram-se adequados à industrialização.

  10. [Acute pulmonary embolism: prediction of cor pulmonale and short-term patient survival from assessment of cardiac dimensions in routine multidetector-row CT].

    Science.gov (United States)

    Engelke, C; Rummeny, E; Marten, K

    2006-10-01

    Evaluation of the prognostic value of morphological cardiac parameters in patients with suspected and incidental acute pulmonary embolism (PE) using multidetector-row chest CT (MSCT). 2335 consecutive MSCT scans were evaluated for the presence of PE. The arterial enhancement and analysability of pulmonary arteries and the heart were assessed as parameters of the scan quality. The diastolic right and left ventricular short axes (RV (D), LV (D)) and the interventricular septal deviation (ISD) were measured in all PE-positive patients and the echocardiography reports were reviewed. The clinical data assessment included cardio-respiratory and other co-morbidities, systemic anticoagulant therapy (ACT), and the 30-day outcome. Predictors of acute cor pulmonale and the short-term outcome were calculated by univariate and multivariate logistic regressions including odds ratios (OR) and ROC analyses using positive (PPV) and negative predictive values (NPV). 90 patients with acute PE were included (36 with clinically suspected PE, 54 with incidental PE). 26 patients had cardio-respiratory co-morbidities. Four patients underwent systemic thrombolysis, 43 underwent anticoagulation in therapeutic doses, 19 underwent anticoagulation in prophylactic doses, and 24 patients did not undergo ACT. 15 of 41 patients had echocardiographic evidence of acute cor pulmonale. 8 patients died within 30 days. The RV (D) was the best independent predictor of acute cor pulmonale (p = 0,002, OR = 9.16, PPV = 0.68, NPV = 1 at 4.49 cm cut off) and short-term outcome (p = 0,0005, OR = 2.82, PPV = 0.23, NPV = 0.98 at 4.75 cm cut off). The RV (D)/LV (D) ratio had a PPV of 0.85 for cor pulmonale. The RV (D) and RV (D)/LV (D) ratio were suitable for identifying patients with acute cor pulmonale and for benign short-term prognosis. Further studies should prospectively address the combined use of CT-morphological and clinical parameters for the prediction of patient outcome.

  11. Estimation of leaf area index for cotton canopies using the LI-COR LAI-2000 plant canopy analyzer

    International Nuclear Information System (INIS)

    Hicks, S.K.; Lascano, R.J.

    1995-01-01

    Measurement of leaf area index (LAI) is useful for understanding cotton (Gossypium hirsutum L.) growth, water use, and canopy light interception. Destructive measurement is time consuming and labor intensive. Our objective was to evaluate sampling procedures using the Li-Cor (Lincoln, NE) LAI 2000 plant canopy analyzer (PCA) for nondestructive estimation of cotton LAI on the southern High Plains of Texas. We evaluated shading as a way to allow PCA measurements in direct sunlight and the influence of solar direction when using this procedure. We also evaluated a test of canopy homogeneity (information required for setting PCA field of view), determined the number of below-canopy measurements required, examined the influence of leaf wilting on PCA LAI determinations, and tested an alternative method (masking the sensor's two outer rings) for calculating LAI from PCA measurements. The best agreement between PCA and destructively measured LAI values was obtained when PCA observations were made either during uniformly overcast conditions or around solar noon using the shading method. Heterogeneous canopies with large gaps between rows required both a restricted (45 degrees) azimuthal field of view and averaging the LAI values for two transects, made with the field of view parallel and then perpendicular to the row direction. This method agreed well (r2 = 0.84) with destructively measured LAI in the range of 0.5 to 3.5 and did not deviate from a 1:1 relationship. The PCA underestimated LAI by greater than or equal 20% when measurements were made on canopies wilted due to water stress. Masking the PCA sensor's outer rings did not improve the relationship between estimated and measured LAI in the range of LAI sampled

  12. Mapeamento do fósforo adsorvido por meio da cor e da suscetibilidade magnética do solo

    Directory of Open Access Journals (Sweden)

    Rafael Gonçalves Peluco

    2015-03-01

    Full Text Available O objetivo deste trabalho foi avaliar a possibilidade de se mapear o fósforo adsorvido por meio da avaliação da cor e da suscetibilidade magnética do solo. O experimento foi realizado em área de cana-de-açúcar com 380 ha, que compreendia quatro tipos de Latossolos, com diferentes texturas e fertilidades naturais. Foram coletadas 241 amostras de solo, na profundidade de 0,00-0,25 m. O índice de avermelhamento do solo foi calculado a partir dos valores de matiz, valor e croma das amostras, obtidos com espectroscopia de reflectância difusa. Foram ajustados modelos de regressão entre o fósforo adsorvido e a suscetibilidade magnética ou o índice de avermelhamento dos solos. A dependência espacial dos dados foi avaliada por meio de geoestatística. A suscetibilidade magnética correlaciona-se significativamente ao fósforo adsorvido, o que possibilita seu uso como componente de funções de pedotransferência para quantificação indireta do fósforo adsorvido ao solo. O índice de avermelhamento e a suscetibilidade magnética apresentam dependência espacial com o fósforo adsorvido. A suscetibilidade magnética e o índice de avermelhamento dos solos, avaliado pela espectroscopia de reflectância difusa, podem auxiliar no mapeamento e na identificação de áreas com diferentes potenciais de adsorção de fósforo.

  13. Melanoma de corpo ciliar e coróide: relato de caso Choroidal and ciliary body melanoma: case report

    Directory of Open Access Journals (Sweden)

    Aline Amaral Fulgêncio da Cunha

    2010-04-01

    Full Text Available Melanomas oculares correspondem a 5% de todos os melanomas e 85% deles têm origem no trato uveal. Melanoma uveal é o tumor maligno intraocular primário mais comum no adulto. Relatamos neste artigo um caso de melanoma uveal em paciente, sexo feminino, 31 anos, com quadro de fotopsia, hiperemia e baixa da acuidade visual no olho esquerdo com evolução de quatro meses. Apresentava ao exame oftalmológico acuidade visual menor que 20/400, grande massa tumoral na região nasal retroiriana, com deslocamento anterior do cristalino, estreitamento da câmara anterior e descolamento seroso da retina. A ecografia sugeriu tratar-se de grande massa tumoral suspeita de melanoma de coróide com invasão do corpo ciliar. A confirmação diagnóstica foi possível por meio do exame anatomopatológico.Ocular melanomas correspond to 5% of all melanomas and 85% of them have its origin in the uveal tract. Uveal melanoma is the most commom primary intraocular malignant tumor in the adult. In this article, a case of uveal melanoma in a 31 year-old female patient, with photopsia, hyperemia and low visual acuity in the left eye with evolution of 4 months is presented. In the ophthalmologic examination, visual acuity was lower than 20/400, a large tumoral mass was noted at the nasal region behind the iris with anterior lens displacement, anterior chamber narrowing and serous retinal detachment. The ocular echography suggested a large tumoral mass as a choroidal melanoma extending to the ciliary body. The confirmation diagnosis was possible through the histopathologic examination.

  14. Esquistossomose pulmonar. II. Forma crônica reativada com hipertensão e Cor pulmonale

    Directory of Open Access Journals (Sweden)

    Jayme Neves

    1980-12-01

    Full Text Available Os Autores descrevem um caso grave de esquistossomose mansoni (forma hepática com hipertensão portal associada a forma pulmonar com hipertensão pulmonar e cor pulmonalej sobre o qual evoluiu uma sindrome toxi-infectuosa grave e de longa duração. Sucessivos exames radiológicos do tórax revelaram acometimento predominantemente arteriolar, ao lado de uma micronodulação pulmonar grosseira e difusa em ambos os hemitóraces e configuração de coração pulmonar. A histopatologia de material de biópsia pulmonar identificou basicamente uma arterite pulmonar característica, inflamação granulomatosa atípica provocada principalmente por vermes e raros ovos de S. mansoni envolvidos por escassa reação inflamatória. Para explicar a origem de constelação clínica toxi-infectuosa, foram afastadas as hipóteses de associação da esquistossomose a concausas infectuosas ou não, mas de curso febril, e a superposição de uma forma toxêmica sobre outra crônica pré-existente. Com base em dados clínicos, particularmente em subsídios da laparoscopia, e anatômicos, concluiu-se tratar o caso de uma forma crônica de esquistossomose reativada, provavelmente em virtude de alterações imunológicas inusitadas do hospedeiro. Ao que tudo parece indicar, o desvio de ovos e de vermes aos pulmões deveu-se à sindrome de hipertensão portal, cujos shunts entre a circulação portal e sistêmica determinaram a rota preferencial da migração.

  15. Pterostilbene reduces oxidative stress, prevents hypertrophy and preserves systolic function of right ventricle in cor pulmonale model.

    Science.gov (United States)

    Dos Santos Lacerda, Denise; Türck, Patrick; Gazzi de Lima-Seolin, Bruna; Colombo, Rafael; Duarte Ortiz, Vanessa; Poletto Bonetto, Jéssica Hellen; Campos-Carraro, Cristina; Bianchi, Sara Elis; Belló-Klein, Adriane; Linck Bassani, Valquiria; Sander da Rosa Araujo, Alex

    2017-10-01

    In cor pulmonale, the increased afterload imposed on the right ventricle (RV) generates a maladaptive response, impairing the contractile cardiac function. Oxidative mechanisms play an important role in the pathophysiology and progression of this disease. The administration of pterostilbene (PTS), a phytophenol with antioxidant potential, may represent a therapeutic option. In the present study, we evaluated the effect of PTS complexed with hydroxypropyl-β-cyclodextrin (HPβCD) on hypertrophy, contractile function and oxidative parameters in the RV of rats with pulmonary hypertension, induced by the administration of monocrotaline (MCT). The rats received daily doses of the PTS : HPβCD complex at 25, 50 or 100 mg·kg -1 , p.o., for 14 days. The diastolic function, E/A ratio, and systolic function, shortening fraction, fractional area change (FAC) and tricuspid annular plane systolic excursion (TAPSE) of the RV were determined by echocardiography. The PTS : HPβCD complex reduced the production of NADPH oxidase-dependent superoxide anions and oxidative stress in the RV of MCT-treated rats in a dose-dependent manner. At higher doses it prevented the reduction in FAC and TAPSE in MCT-treated animals. The PTS : HPβCD complex prevented the maladaptative remodelling and protected systolic function in the RV of rats with pulmonary hypertension. These cardioprotective mechanisms may be related, in part, to the antioxidant potential of PTS, favoured by the increased p.o. bioavailability promoted by the presence of HPβCD in the complex. © 2017 The British Pharmacological Society.

  16. Acute respiratory distress syndrome (ARDS)-associated acute cor pulmonale and patent foramen ovale: a multicenter noninvasive hemodynamic study.

    Science.gov (United States)

    Legras, Annick; Caille, Agnès; Begot, Emmanuelle; Lhéritier, Gwenaëlle; Lherm, Thierry; Mathonnet, Armelle; Frat, Jean-Pierre; Courte, Anne; Martin-Lefèvre, Laurent; Gouëllo, Jean-Paul; Mercier, Emmanuelle; Vignon, Philippe

    2015-04-17

    Acute cor pulmonale (ACP) and patent foramen ovale (PFO) remain common in patients under protective ventilation for acute respiratory distress syndrome (ARDS). We sought to describe the hemodynamic profile associated with either ACP or PFO, or both, during the early course of moderate-to-severe ARDS using echocardiography. In this 32-month prospective multicenter study, 195 patients with moderate-to-severe ARDS were assessed using echocardiography during the first 48 h of admission (age: 56 (SD: 15) years; Simplified Acute Physiology Score: 46 (17); PaO2/FiO2: 115 (39); VT: 6.5 (1.7) mL/kg; PEEP: 11 (3) cmH2O; driving pressure: 15 (5) cmH2O). ACP was defined by the association of right ventricular (RV) dilatation and systolic paradoxical ventricular septal motion. PFO was detected during a contrast study using agitated saline in the transesophageal bicaval view. ACP was present in 36 patients, PFO in 21 patients, both PFO and ACP in 8 patients and the 130 remaining patients had neither PFO nor ACP. Patients with ACP exhibited a restricted left ventricle (LV) secondary to RV dilatation and had concomitant RV dysfunction, irrespective of associated PFO, but preserved LV systolic function. Despite elevated systolic pulmonary artery pressure (sPAP), patients with isolated PFO had a normal RV systolic function. sPAP and PaCO2 levels were significantly correlated. In patients under protective mechanical ventilation with moderate-to-severe ARDS, ACP was associated with LV restriction and RV failure, whether PFO was present or not. Despite elevated sPAP, PFO shunting was associated with preserved RV systolic function.

  17. Tomografia de coerência óptica em osteoma de coróide: relato de caso Optical coherence tomography in choroidal osteoma: case report

    Directory of Open Access Journals (Sweden)

    Mário Junqueira Nóbrega

    2005-10-01

    Full Text Available Os autores apresentam um caso de osteoma de coróide diagnosticado em paciente do sexo masculino aos 62 anos de idade. A lesão bem delimitada e pouco elevada no pólo posterior do olho direito acompanhada de vascularização interna e neovascularização de coróide em sua borda temporal superior e inferior levaram à suspeita do tumor. O diagnóstico de certeza foi obtido com ecografia A e B e tomografia computadorizada. A tomografia de coerência óptica mostrou alta refletividade em toda a espessura do osteoma bem como elevação do complexo EPR-cório-capilar na região da membrana neovascular subretiniana. Embora os achados tomográficos descritos na literatura e os observados neste caso sejam variados, a tomografia de coerência óptica pode colaborar no diagnóstico de osteoma de coróide.The authors present a case of choroidal osteoma diagnosed in a 62-year-old male patient. A well-defined and slightly elevated lesion located in the posterior pole of the right eye associated with internal vasculature and choroidal neovascularization at its superior and inferior temporal edge were suspicious of the tumor. Confirmation of diagnosis was obtained with A and B ecography and computed tomography. Optical coherence tomography showed high reflectivity through its thickness as well as elevation of the RPE-choriocapillaris complex at the choroidal neovascularization site. Although the literature and the present case show several different tomographical findings, optical coherence tomography can help establishing the diagnosis of choroidal osteoma.

  18. In Vitro Evaluation of ECG-Synchronized Pulsatile Flow Using the i-cor Diagonal Pump in Neonatal and Pediatric ECLS Systems.

    Science.gov (United States)

    Moroi, Morgan; Force, Madison; Wang, Shigang; Kunselman, Allen R; Ündar, Akif

    2018-02-23

    The objective was to assess the i-cor electrocardiogram-synchronized diagonal pump in terms of hemodynamic energy properties for off-label use in neonatal and pediatric extracorporeal life support (ECLS) circuits. The neonatal circuit consisted of an i-cor pump and console, a Medos Hilite 800 LT oxygenator, an 8Fr arterial cannula, a 10Fr venous cannula, 91 cm of 0.6-cm ID arterial tubing, and 91 cm of 0.6-cm ID venous tubing. The pediatric circuit was identical except it included a 12Fr arterial cannula, a 14Fr venous cannula, and a Medos Hilite 2400 LT oxygenator. Neonatal trials were conducted at 36°C with hematocrit 40% using varying flow rates (200-600 mL/min, 200 mL increments) and postarterial cannula pressures (40-100 mm Hg, 20 mm Hg increments) under nonpulsatile mode and pulsatile mode with various pulsatile amplitudes (1000-4000 rpm, 1000 rpm increments). Pediatric trials were conducted at different flow rates (800-1600 mL/min, 400 mL/min increments). Mean pressure and energy equivalent pressure increased with increasing postarterial cannula pressure, flow rate, and pulsatile amplitude. Physiologic-like pulsatility was achieved between pulsatile amplitudes of 2000-3000 rpm. Pressure drops were greatest across the arterial cannula. Pulsatile flow generated significantly higher total hemodynamic energy (THE) levels than nonpulsatile flow. THE levels at postarterial cannula site increased with increasing postarterial cannula pressure, pulsatile amplitude, and flow rate. No surplus hemodynamic energy (SHE) was generated under nonpulsatile mode. Under pulsatile mode, preoxygenator SHE increased with increasing postarterial cannula pressure and pulsatile amplitude, but decreased with increasing flow rate. The i-cor system can provide nonpulsatile and pulsatile flow for neonatal and pediatric ECLS. Pulsatile amplitudes of 2000-3000 rpm are recommended for use in neonatal and pediatric patients. © 2018 International Center for Artificial Organs and

  19. Alterações da atividade de água e da cor da carne no processo de elaboração da carne salgada desidratada

    Directory of Open Access Journals (Sweden)

    SABADINI E.

    2001-01-01

    Full Text Available Carne salgada desidratada é um produto largamente usado no Brasil, como fonte de proteína animal. O principal objetivo deste tipo de processamento é a remoção de água, inicialmente por mudanças de pressão osmótica e, a seguir por secagem, levando a um produto com umidade intermediária, como o charque e o "jerked beef". O processo de desidratação osmótica, pela penetração do sal e saída de água, causa redução nos níveis de atividade de água. Alterações de cor também ocorrem durante o processamento. Neste trabalho, estas duas variáveis são avaliadas, em pedaços de carne submetidos à salga seca e úmida. Os valores de atividade de água iniciais foram reduzidos em ambas as etapas, sendo mais acentuado para salga seca, obtendo ao término desse experimento 0,79 unidades a 10ºC e 0,75 a 20ºC. Os efeitos do sal também alteraram os parâmetros de cor, afetando os valores de L* a* b*, e direta e diferentemente o valor de DE das salgas. O estudo dos parâmetros de cor e da atividade de água é útil para um melhor conhecimento e controle do processo de carne salgada desidratada.

  20. AVALIAÇÃO DA ESTABILIDADE DE COR DE LAMINADOS CERÂMICOS APÓS CIMENTAÇÃO ADESIVA

    OpenAIRE

    ANTONIO SETSUO SAKAMOTO JUNIOR

    2015-01-01

    A modalidade indireta de restauração denominada laminado cerâmico, vem sendo vastamente solicitada pelos pacientes, por se tratar de um procedimento confiável, estável, conservador, estético e apresenta longevidade aceitável. Sabe-se que a alteração de cor do cimento localizado abaixo destas restaurações delgadas pode influenciar negativamente no aspecto estético final. Desta forma, o propósito do presente estudo in vitro foi avaliar a concordância da coloração da pasta de prova e seu resp...

  1. Structure de propriété, stratégies de diversification et gouvernance des entreprises coréennes

    OpenAIRE

    Lee, Joon Tae

    2005-01-01

    L’objectif de cette thèse est d’étudier la structure de propriété des entreprises coréennes. Nous analysons comment les familles à la tête des chaebols organisent la structure de l’actionnariat afin de contrôler toutes les entreprises du groupe avec un faible pourcentage de capital, et comment cette structure de propriété influe sur les choix stratégiques, notamment sur la diversification, la gouvernance d’entreprise et la performance. Notre analyse distingue deux périodes d’analyse (avant et...

  2. Influência das condições de armazenamento sobre os pigmentos cárneos e a cor do salame italiano fatiado

    OpenAIRE

    Marches,Cristiane Michele; Cichoski,Alexandre José; Zanoelo,Everton Fernando; Dariva,Cláudio

    2006-01-01

    O consumo de produtos cárneos fatiados tem aumentado nos últimos anos, particularmente os produtos curados como o salame. Os vários tipos de salame existentes são fatiados pelas indústrias de carne e/ou pelos supermercados, sem levar em conta as possíveis alterações que possam vir a ocorrer com tal procedimento. As alterações que ocorrem nos pigmentos cárneos totais e nitrosos repercutem na cor, que é detectada pelo consumidor e influencia diretamente no consumo de produtos desta natureza. O ...

  3. Efeito de diferentes fotopolimerizadores e meio de imersão na rugosidade e na cor de um compósito nanoparticulado

    OpenAIRE

    PLASTER,Suéllen Campos; PEIXOTO,Letícia Monteiro; GUEDES,Ana Paula Albuquerque; SILVA,Daniela Nascimento; CASTRO,Martha Chiabai Cupertino

    2016-01-01

    Resumo Introdução O consumo excessivo de refrigerantes parece alterar as propriedades dos compósitos e essa alteração pode estar relacionada à unidade fotopolimerizadora. Objetivo Avaliar a alteração da rugosidade superficial (ΔR) e da cor (ΔE) de um compósito polimerizado por diferentes fotopolimerizadores, imerso em água destilada ou Coca-Cola®. Metodologia Sessenta amostras da resina nanoparticulada (FiltekMR Z350 XT, 3M) foram distribuídas de acordo com as diferentes unidades...

  4. Acute pulmonary embolism on MDCT of the chest: prediction of cor pulmonale and short-term patient survival from morphologic embolus burden.

    Science.gov (United States)

    Engelke, Christoph; Rummeny, Ernst J; Marten, Katharina

    2006-05-01

    To predict cor pulmonale and short-term outcome in patients with pulmonary embolism (PE), we retrospectively investigated three morphology-based MDCT systems for scoring pulmonary artery obstruction. Eighty-nine consecutive patients (51 men and 38 women; age range, 23-83 years; median, 63.3 years) with an MDCT diagnosis of acute PE were included in the study. Sixty-four patients had a coexisting malignancy. PE severity was assessed by two masked observers using three percentage arterial obstruction indexes: two severity scores adapted from conventional angiography (excluding and including arterial branch obstruction grading: scores A and B, respectively) and a CT-derived severity score (index C). Echocardiographic reports were reviewed for elevation of right ventricular pressure. Obstruction index results were analyzed for correlation with pulmonary artery pressures and for prediction of cor pulmonale and 30-day survival. Statistical analysis included kappa, analysis of variance, linear correlation, chi-square, and logistic regression tests. Kappa values of 0.89, 0.82, and 0.78 were obtained for interobserver agreement on PE severity for indexes A, B, and C, respectively. PE severity was moderate but varied significantly between the scores (for index A: median, 25.0%; range, 6.3-100; for index B: median, 12.5%; range, 3.1-65.6; for index C: median, 7.1%; range, 0.65-65.8; p cor pulmonale (p = 0.0051; odds ratio [OR], 1.20/percentage increase [95% confidence interval, 1.05-1.35]; for an index C cutoff of 21.3%: p = 0.0001; positive predictive value, 1; negative predictive value, 0.87). Eight patients died within 30 days after CT. The PE severity of indexes A and B was not associated with patient outcome (p > 0.05). With score C, PE severity was a significant predictor of early death (p = 0.018; OR, 1.03/percentage increase [95% confidence interval, 1.00-1.06]; for an index C cutoff of 21.3%: p = 0.018; overall OR, 6.77; positive predictive value, 0.24; negative

  5. COR1 Engineering Test Unit Measurements at the NCAR/HAO Vacuum Tunnel Facility, October-November 2002

    Science.gov (United States)

    Thompson, William

    2002-01-01

    The Engineering Test Unit (ETU) of COR1 was made in two configurations. The first configuration, ETU-1, was for vibration testing, while the second, ETU-2, was for optical testing. This is a report on the optical testing performed on ETU-2 at the NCAR/HAO Vacuum Tunnel Facility during the months of October and November, 2002. This was the same facility used to test the two previous breadboard models. In both configurations, the first two tube sections were complete, with all optical elements aligned. The vibration model ETU-1 had the remaining tube sections attached, with mass models for the remaining optics, for the various mechanisms, and for the focal plane assembly. It was then converted into the optical model ETU-2 by removing tube sections 3 to 5, and mounting the remaining optics on commercial mounts. (The bandpass filter was also installed into tube 2, which had been replaced in ETU-1 by a mass model, so that pre- and post-vibration optical measurements could be made.) Doublet 2 was installed in a Newport LP-2 carrier, and aligned to the other optics in the first two tube sections. The LP-2 adjustment screws were then uralened so that the alignment could be maintained during shipping. Because neither the flight polarizer nor Hollow Core Motor were available, they were simulated by a commercial polarizer and rotational mount, both from Oriel corporation. The Oriel rotational stage was not designed for vacuum use, but it was determined after consultation with the company, and lab testing, that the stage could be used in the moderate vacuum conditions at the NCAR/HAO facility. The shutter and focal plane assembly were simulated with the same camera used for the previous two breadboard tests. The focal plane mask was simulated with a plane of BK7 glass with a mask glued on, using the same procedure as for the Lyot spot on Doublet 1, and mounted in an adjustable LP-2 carrier. Two masks were made, one made to the precise specifications of the optical design, the

  6. Cinética da degradação da cor de solução hidrossolúvel comercial de urucum, submetida a tratamentos térmicos

    OpenAIRE

    FERREIRA,Vera Lúcia Pupo; TEIXEIRA NETO,Rodrigo Otávio; MOURA,Silvia Cristina Sobottka Rolim de; SILVA,Marcelo Souza

    1999-01-01

    Soluções comerciais hidrossolúveis de urucum foram submetidas a diferentes tratamentos de tempo/temperatura, a fim de se investigar a estabilidade da cor nestas condições. A cor foi medida em um espectrofotômetro COMCOR 1500 Plus no sistema Lab Hunter e os resultados são discutidos neste artigo, assim como as alterações de concentração do sal de norbixina e os parâmetros de cor L, a e b Hunter. Os resultados foram analisados quanto à ordem da reação e a dependência da temperatura pôde ser des...

  7. Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9

    Directory of Open Access Journals (Sweden)

    Shuangquan Yan

    2016-01-01

    Full Text Available Baicalin has a protective effect on hypoxia-induced pulmonary hypertension in rats, but the mechanism of this effect remains unclear. Thus, investigating the potential mechanism of this effect was the aim of the present study. Model rats that display hypoxic pulmonary hypertension and cor pulmonale under control conditions were successfully generated. We measured a series of indicators to observe the levels of pulmonary arterial hypertension, pulmonary arteriole remodeling, and right ventricular remodeling. We assessed the activation of p38 mitogen-activated protein kinase (MAPK in the pulmonary arteriole walls and pulmonary tissue homogenates using immunohistochemistry and western blot analyses, respectively. The matrix metalloproteinase- (MMP- 9 protein and mRNA levels in the pulmonary arteriole walls were measured using immunohistochemistry and in situ hybridization. Our results demonstrated that baicalin not only reduced p38 MAPK activation in both the pulmonary arteriole walls and tissue homogenates but also downregulated the protein and mRNA expression levels of MMP-9 in the pulmonary arteriole walls. This downregulation was accompanied by the attenuation of pulmonary hypertension, arteriole remodeling, and right ventricular remodeling. These results suggest that baicalin may attenuate pulmonary hypertension and cor pulmonale, which are induced by chronic hypoxia, by downregulating the p38 MAPK/MMP-9 pathway.

  8. Proteinas do liquido cefalorraqueano: II. Valores normais das frações proteicas obtidas por eletroforese (variações ligadas a cor, sexo e idade

    Directory of Open Access Journals (Sweden)

    Lucia M. Singer Vermes

    1983-03-01

    Full Text Available Mediante dosagens de proteínas totais e eletroforese sobre acetato de celulose de 213 amostras de LCR normal, obtidas por punção da cisterna magna, foram efetuados estudos para verificação de variações ligadas à cor, sexo e idade. Os resultados obtidos permitiram concluir que: 1. não existem diferenças ligadas à cor no proteinograma do LCR; 2. em crianças, os fatores sexo e idade não influem nos valores estudados; 3. as taxas de proteínas totais e frações protéicas do LCR normal de criança diferem das de homens e de mulheres; 4. em adultos ocorrem variações ligadas ao sexo no proteinograma do LCR; 5. em adultos, proteínas totais e todas frações protéicas, quando expressas em mg/100 ml, aumentam com o avançar da idade. Foram estabelecidas, para a metodologia usada, as taxas fisiológicas do proteinograma do LCR de crianças, homens e mulheres, separadamente.

  9. Variação da Cor da Madeira de Teca em Função da Densidade e do Teor de Extrativos

    Directory of Open Access Journals (Sweden)

    Rosilei Aparecida Garcia

    Full Text Available RESUMO O objetivo deste estudo foi avaliar o efeito da densidade e do teor de extrativos na variação da cor da madeira de teca (Tectona grandis L. f. proveniente de plantios de diferentes espaçamentos. As análises colorimétricas foram realizadas nas faces radial e tangencial das madeiras de cerne e alburno com o espectrofotômetro CM 2600d no espaço de cor L*a*b*. A densidade e o teor de extrativos foram determinados segundo as normas ASTM D2395 e ASTM D1105. A madeira do maior espaçamento de plantio apresentou maior densidade e maior teor de extrativos. Na seção radial, as madeiras de cerne de maior densidade apresentaram mais pigmento amarelo, enquanto que na seção tangencial elas são mais escuras e apresentam menos pigmento amarelo. As madeiras de alburno de maior densidade são mais escuras e apresentam mais pigmento vermelho em ambas as seções. As madeiras mais escuras e com mais pigmento vermelho apresentaram um maior teor de extrativos.

  10. Calculating length of gestation from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) database versus vital records may alter reported rates of prematurity.

    Science.gov (United States)

    Stern, Judy E; Kotelchuck, Milton; Luke, Barbara; Declercq, Eugene; Cabral, Howard; Diop, Hafsatou

    2014-05-01

    To compare length of gestation after assisted reproductive technology (ART) as calculated by three methods from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) and vital records (birth and fetal death) in the Massachusetts Pregnancy to Early Life Longitudinal Data System (PELL). Historical cohort study. Database linkage analysis. Live or stillborn deliveries. None. ART deliveries were linked to live birth or fetal death certificates. Length of gestation in 7,171 deliveries from fresh autologous ART cycles (2004-2008) was calculated and compared with that of SART CORS with the use of methods: M1 = outcome date - cycle start date; M2 = outcome date - transfer date + 17 days; and M3 = outcome date - transfer date + 14 days + day of transfer. Generalized estimating equation models were used to compare methods. Singleton and multiple deliveries were included. Overall prematurity (delivery 45% of deliveries and by more than 1 week in >22% of deliveries. Each method differed from each other. Estimates of preterm birth in ART vary depending on source of data and method of calculation. Some estimates may overestimate preterm birth rates for ART conceptions. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  11. Alterações oxidativas (cor e lipídios em presunto de peru tratado por Alta Pressão Hidrostática (APH

    Directory of Open Access Journals (Sweden)

    Simone Pereira Mathias

    2010-12-01

    Full Text Available A Alta Pressão Hidrostática (APH consiste em uma tecnologia inovadora de processamento de alimentos com utilização de pressões elevadas (100 a 900 MPa que possui vantagens em relação às tecnologias térmicas convencionais, pois mantém as características sensoriais do alimento próximas do original e garante segurança do ponto de vista microbiológico, por prolongado período de vida útil. No presente estudo, foi avaliada a aplicação de alta pressão a presunto de peru nos processos oxidativos, em particular na oxidação de lipídios e os efeitos na cor do produto, quando tratados a pressões de 200 a 400 MPa, por 5, 10 e 15 minutos em temperatura ambiente. Dos resultados obtidos, pode-se observar que não foram verificadas diferenças significativas (p > 0,05 entre amostras controle e pressurizada para o índice de TBA e índice de peróxido. Foi observado também alteração da cor decorrente de reações oxidativas aos 45 e 65 dias de armazenamento em amostras tratadas com pressões de 400 MPa a 5 e 15 minutos

  12. A new concept for the non-invasive treatment of Adolescent Idiopathic Scoliosis: the Corrective Movement principle integrated in the SpineCor System.

    Science.gov (United States)

    Coillard, Christine; Circo, Alin; Rivard, Charles H

    2008-05-01

    To evaluate the change in spinal curvature and posture of Idiopathic Scoliosis patients when a curve specific 'Corrective Movement Principle' (CMP) is applied. This prospective interventional study was carried out on a group of 639 patients (92.3% females) having idiopathic scoliosis treated with the SpineCor brace. All girls were premenarchal or less than 1 year postmenarchal. Assessment of brace effectiveness followed the SRS outcome criteria for bracing. The clinical, radiological and postural evaluations assisted to define the patient classification, which guided the unique application of the CMP to each type of curvature. A total of 583 patients met the outcome criteria. Overall, 349 patients have a definitive outcome. Successful treatment was achieved in 259 (74.2%) of the 349 patients from the fitting to the weaning of the brace. Some 51 immature patients (14.6%) required surgical fusion while receiving treatment. Eight mature patients out of 298 (2.7%) required surgery within 2 years of follow-up beyond skeletal maturity. The SpineCor brace is effective for the treatment of adolescent idiopathic scoliosis. Moreover, positive outcomes are maintained after 2 years because 151 (93.2%) of 162 patients stabilized or corrected their end of bracing Cobb angle up to 2 years after bracing.

  13. A prospective randomized controlled trial of the natural history of idiopathic scoliosis versus treatment with the SpineCor brace. Sosort Award 2011 winner.

    Science.gov (United States)

    Coillard, C; Circo, A B; Rivard, C H

    2014-10-01

    The purpose of this randomized controlled trial was to evaluate the efficacy of the Dynamic SpineCor brace for early idiopathic scoliosis (15°-30°) compared to the natural evolution of the disease. 68 patients participated in this study (32 treated and 36 controls) with at least 5 years follow-up. The inclusion criteria were: 1) high risk of evolution: family history and/or proven progressive; 2) no significant pathological malformation of the spine; 3) initial Cobb angle between 15° and 30°; 4) risser 0, 1 or 2. Assessment of brace efficacy included the percentage of patients who have 5º or less curve progression and the percentage of patients who have 6º or more progression at skeletal maturity. At five-year follow-up a correction was achieved in 50% of treated patient and only in 9.5% of controls, stabilization in 42.3% treated and 47.7% in controls and progression in 26.9% for the treated group and 42.8% for controls. For the control patients we considered as a failure if the Cobb angle worsened by more then 5° from the original angle and the patient then received treatment. The results 5 years after the treatment suggested that the SpineCor brace reduced the probability of the progression of early idiopathic scoliosis comparing with its natural history. Moreover, the positive outcome appears to be maintained in the long term.

  14. Racismo e saúde: representações sociais de mulheres e profissionais sobre o quesito cor/raça

    Directory of Open Access Journals (Sweden)

    Amália Nascimento do Sacramento

    2011-10-01

    Full Text Available Trata-se de um estudo com abordagem multimetodológica apoiado na Teoria das Representações Sociais, com o objetivo de apreender as representações que o quesito cor tem para usuárias e profissionais de serviços públicos de saúde. Foi realizado em Unidades Básicas de Saúde do município de Salvador com 103 sujeitos. Os dados foram coletados por meio do Teste de Associação Livre de Palavras e da entrevista semiestruturada. Utilizou-se Análise Fatorial de Correspondência e análise temática. Os resultados mostram oposição de respostas entre pessoas que se autoclassificaram como brancas e pretas e oposição entre as pessoas mais jovens e mais velhas do estudo. As representações sobre o quesito cor retratam a complexidade da classificação racial e a necessidade de efetivação de trabalhos sobre políticas de saúde e de raças brasileiras.

  15. Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9.

    Science.gov (United States)

    Yan, Shuangquan; Wang, Yiran; Liu, Panpan; Chen, Ali; Chen, Mayun; Yao, Dan; Xu, Xiaomei; Wang, Liangxing; Huang, Xiaoying

    2016-01-01

    Baicalin has a protective effect on hypoxia-induced pulmonary hypertension in rats, but the mechanism of this effect remains unclear. Thus, investigating the potential mechanism of this effect was the aim of the present study. Model rats that display hypoxic pulmonary hypertension and cor pulmonale under control conditions were successfully generated. We measured a series of indicators to observe the levels of pulmonary arterial hypertension, pulmonary arteriole remodeling, and right ventricular remodeling. We assessed the activation of p38 mitogen-activated protein kinase (MAPK) in the pulmonary arteriole walls and pulmonary tissue homogenates using immunohistochemistry and western blot analyses, respectively. The matrix metalloproteinase- (MMP-) 9 protein and mRNA levels in the pulmonary arteriole walls were measured using immunohistochemistry and in situ hybridization. Our results demonstrated that baicalin not only reduced p38 MAPK activation in both the pulmonary arteriole walls and tissue homogenates but also downregulated the protein and mRNA expression levels of MMP-9 in the pulmonary arteriole walls. This downregulation was accompanied by the attenuation of pulmonary hypertension, arteriole remodeling, and right ventricular remodeling. These results suggest that baicalin may attenuate pulmonary hypertension and cor pulmonale, which are induced by chronic hypoxia, by downregulating the p38 MAPK/MMP-9 pathway.

  16. Validation of birth outcomes from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS): population-based analysis from the Massachusetts Outcome Study of Assisted Reproductive Technology (MOSART).

    Science.gov (United States)

    Stern, Judy E; Gopal, Daksha; Liberman, Rebecca F; Anderka, Marlene; Kotelchuck, Milton; Luke, Barbara

    2016-09-01

    To assess the validity of outcome data reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) compared with data from vital records and the birth defects registry in Massachusetts. Longitudinal cohort. Not applicable. A total of 342,035 live births and fetal deaths from Massachusetts mothers giving birth in the state from July 1, 2004, to December 31, 2008; 9,092 births and fetal deaths were from mothers who had conceived with the use of assisted reproductive technology (ART) and whose cycle data had been reported to the SART CORS. Not applicable. Percentage agreement between maternal race and ethnicity, delivery outcome (live birth or fetal death), plurality (singleton, twin, or triplet+), delivery date, and singleton birth weight reported in the SART CORS versus vital records; sensitivity and specificity for birth defects among singletons as reported in the SART CORS versus the Massachusetts Birth Defects Monitoring Program (BDMP). There was >95% agreement between the SART CORS and vital records for fields of maternal race/ethnicity, live birth/fetal death, and plurality; birth outcome date was within 1 day with 94.9% agreement and birth weight was within 100 g with 89.6% agreement. In contrast, sensitivity for report of any birth defect was 38.6%, with a range of 18.4%-50.0%, for specific birth defect categories. Although most SART CORS outcome fields are accurately reported, birth defect variables showed poor sensitivity compared with the gold standard data from the BDMP. We suggest that reporting of birth defects be discontinued. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  17. Trouver la bonne distance : étrangère, marginale, ethnologue et parente en Corée du Sud

    Directory of Open Access Journals (Sweden)

    Élise Prébin

    2009-03-01

    Full Text Available Trouver la bonne distance : étrangère, marginale, ethnologue et parente en Corée du Sud. Cet article a pour sujet ma relation à la société sud-coréenne, non seulement en tant qu’anthropologue mais aussi en tant que personne adoptée d’origine coréenne. Il relate la manière dont plusieurs sortes de relations ont dû être gérées pendant le terrain. Il a fallu d’un côté me rapprocher de mes informateurs pour pouvoir mener un terrain classique dans une société inconnue, comprendre une culture autre et traiter un sujet relevant des sciences sociales : le retour des adoptés étrangers dans leur pays d’origine. De l’autre, il a fallu établir une bonne distance avec ma famille biologique coréenne en m’en éloignant momentanément. Ma relation avec elle était en effet instable du fait qu’elle reposait sur une contradiction : mon statut d’étrangère en dépit de l’intimité que supposaient les liens du sang. Pourtant, cette relation continue entre ma famille biologique et moi-même a éclairé certaines ambiguïtés relatives au statut des adoptés dans la société sud-coréenne que le temps limité du terrain n’avait pas permis de saisir. Cet article ébauche donc une réflexion épistémologique sur la pertinence d’éléments biographiques dans le traitement anthropologique de certains sujets. Je montre en l’occurrence comment le don en mariage d’une fille biologique adoptée conjure de manière satisfaisante un don en adoption toujours problématique.Finding the right distance: stranger, marginal, ethnologist and relative in south Korea. The topic of this article is my relation to the South Korean society, not only as a social anthropologist but also as a Korean adoptee. I relate the way I had to manage contrasted relations while conducting fieldwork. On one hand, I endeavoured to get closer to my informants in order to conduct classic fieldwork in an unknown society, to understand a different culture

  18. Cor a 1-reactive T cells and IgE are predominantly cross-reactive to Bet v 1 in patients with birch pollen-associated food allergy to hazelnut.

    Science.gov (United States)

    Hofmann, Claudia; Scheurer, Stephan; Rost, Kathrin; Graulich, Edith; Jamin, Annette; Foetisch, Kay; Saloga, Joachim; Vieths, Stefan; Steinbrink, Kerstin; Adler, Henric S

    2013-05-01

    IgE- and T-cell cross-reactivity contribute to the birch pollen-food syndrome. We performed a comprehensive analysis of T-cell cross-reactivity in primary cell cultures, facilitating the identification of allergen-specific T-cell subpopulations from individual patients. Patients with birch pollen allergy and associated food allergy to hazelnuts, carrots, or both were analyzed for IgE cross-reactivity, T-cell responses, and T-cell cross-reactivity to recombinant Bet v 1.0101 (Bet v 1; birch), Cor a 1.0401 (Cor a 1; hazelnut), and Dau c 1.0104 (Dau c 1; carrot). A novel flow cytometry-based method using a 2-step staining process with fluorescent dyes was established to identify subpopulations of cross-reactive T cells. IgE-binding inhibition tests of individual sera revealed that the vast majority of Cor a 1-reactive IgE was cross-reactive to Bet v 1, whereas Bet v 1-reactive IgE was only partially inhibited by preincubation with Cor a 1. Primary stimulation of T cells with Bet v 1 or Cor a 1 resulted in a significant increase in specific responses to Cor a 1 or Bet v 1 after secondary stimulation, respectively, indicating T-cell cross-reactivity between birch and hazelnut allergens in all patients of the study cohort. Preactivation with Dau c 1 induced less pronounced effects. A novel flow cytometry-based proliferation assay identified a predominant Cor a 1/Bet v 1-cross-reactive T-cell subpopulation within highly Bet v 1/Cor a 1-responsive T cells. Analysis of primary allergen-specific T cells combined with flow cytometry-based proliferation assays facilitates investigation of allergen-specific T-cell subpopulations in subjects and might be helpful to evaluate the effect of birch-specific immunotherapy on pollen-associated food allergies. Copyright © 2012 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  19. Efeitos da luz solar e cor do tanque no desenvolvimento larval e produção de pos-larvas do camarão Macrobrachium rozenbergii (De Man, 1879)

    OpenAIRE

    Rodrigues, Coralucia Chaltein Bello

    1997-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias Agrarias Com a finalidade de se avaliar o efeito da luz solar e a cor dos tanques no desenvolvimento larval e produção de pós-larvas do Macrobrachium rozenbergii, foi conduzido um experimento junto ao laboratório de camarão de água doce do Departamento de Aqüicultura-UFSC. Tanto a luz solar quanto a cor dos tanques (preto e branco) não influenciaram na captura e ingestão de alimentos pelas larvas. Os tanque...

  20. So that We Might Become the Righteousness and Justice of God: Re-examining the Gospel in 2 Cor 5:21 for the Church's Contribution to a Better World

    Directory of Open Access Journals (Sweden)

    Ellington, Dustin W.

    2016-12-01

    Full Text Available This article interprets Paul's summary of the gospel in 2 Cor 5:21 as saying that Christ died so that believers might be transformed into God's righteousness (not only deemed as righteous by God. The article explains the powerfully generative nature of God's righteousness and then demonstrates that dikaiosunē also means justice. The interpretation of 2 Cor 5:21 clarifies that the gospel Christians believe for salvation is also a basis of holistic transformation to embody God's righteousness and justice. This enlarged perspective on the gospel supports seamless invitations to put faith in Jesus Christ and to become a force for justice in the world.

  1. Efeito de diferentes fotopolimerizadores e meio de imersão na rugosidade e na cor de um compósito nanoparticulado

    Directory of Open Access Journals (Sweden)

    Suéllen Campos PLASTER

    Full Text Available Resumo Introdução O consumo excessivo de refrigerantes parece alterar as propriedades dos compósitos e essa alteração pode estar relacionada à unidade fotopolimerizadora. Objetivo Avaliar a alteração da rugosidade superficial (ΔR e da cor (ΔE de um compósito polimerizado por diferentes fotopolimerizadores, imerso em água destilada ou Coca-Cola®. Metodologia Sessenta amostras da resina nanoparticulada (FiltekMR Z350 XT, 3M foram distribuídas de acordo com as diferentes unidades de fotopolimerização: a luz halógena de quartzo-tungstênio-halogênio (QTH; b Luz de Emissão Diodo - LED 1 com ponteira de polímero; c LED 2 com ponteira de fibra ótica. Metade de cada grupo (n=10 foi mantida em água destilada ou imersa em Coca-Cola® 2×/dia por 20 minutos, durante 14 dias. Os dados foram submetidos aos testes Mann-Whitney e Kruskal-Wallis (p≤0,05. Resultado A ΔR não foi significante entre os grupos: em água: QTH = 0,006; LED 1 = 0,019; LED 2 = 0,010 (p=0,33; em refrigerante: QTH = 0,021; LED 1= 0,011; LED 2 = 0,030 (p=0,86. A ΔE não foi significativa entre os fotopolimerizadores: em água: QTH = 1,40; LED 1 = 1,80; LED 2 = 1,60 (p=0,31; em refrigerante: QTH = 2,51; LED 1= 1,91; LED 2 = 2,61 (p=0,41, mas foi significante comparando os meios de imersão (p=0,01, exceto para LED 1 (p=0,54. Conclusão As unidades fotopolimerizadoras não interferiram na rugosidade superficial e na cor da resina composta nanoparticulada. Os mergulhos diários em refrigerante não alteraram a lisura, mas alteraram a cor de modo visualmente perceptível, mas clinicamente aceitável, conforme os parâmetros da literatura científica.

  2. Feasibility of real-time three-dimensional echocardiography for the assessment of distorted biventricular systolic function in patients with cor pulmonale.

    Science.gov (United States)

    Cho, Jung Sun; Youn, Ho-Joong; Cho, Eun-Joo; Her, Sung-Ho; Park, Mahn-Won; Lee, Jae Beum; Choi, Min Seok; Park, Chan Seok

    2013-06-01

    This study was to investigate the feasibility of real-time 3-dimensional echocardiography (RT3DE) for the analysis of biventricular ejection fractions and volume measurements in patients with cor pulmonale and the correlations of RT3DE results with 64-slice multi-detector cardiac computed tomography (64-MDCT) results. This study included a total of 22 patients (59.3 ± 16.6 years of age; 10 males and 12 females) who showed flattening or reverse curvature of the interventricular septum and severe pulmonary hypertension [mean right ventricular (RV) systolic pressure = 66.8 ± 19.7 mmHg] on 2-dimensional transthoracic echocardiography due to cor pulmonale. Biventricular end-diastolic and end-systolic volumes were measured by RT3DE and 64-MDCT. The severity of D-shaped deformation was evaluated by using left ventricular (LV) eccentricity index (ratio of diameters parallel/perpendicular to the interventricular septum on parasternal short axis images of the papillary muscle level). There were moderate correlations between biventricular volumes measured by RT3DE and 64-MDCT except for LV end-systolic volume (59.8 ± 17.1 vs. 73.2 ± 20.2 mL, r = 0.652, p = 0.001 for LV end-diastolic volume; 30.6 ± 9.1 vs. 30.8 ± 12.5 mL, r = 0.361, p = 0.099 for LV end-systolic volume; 110.1 ± 42.9 vs. 171.1 ± 55.3 mL, r = 0.545, p = 0.009 for RV end-diastolic volume; and 80.9 ± 35.0 vs. 128.7 ± 45.1 mL, r = 0.549, p = 0.005 for RV end-systolic volume respectively). This study suggests that RT3DE may be a modest method for measuring distorted biventricular end-systolic and end-diastolic volumes in patients with cor pulmonale.

  3. Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26 and adiponectin before and after oral glucose uptake in slim adults

    Directory of Open Access Journals (Sweden)

    Schäffler Andreas

    2007-02-01

    Full Text Available Abstract Background Adipose tissue secreted proteins are collectively named adipocytokines and include leptin, adiponectin, resistin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26 and omentin. Several of these adipocytokines influence insulin sensitivity and glucose metabolism and therefore systemic levels may be affected by oral glucose uptake. Whereas contradictory results have been published for leptin and adiponectin, resistin has not been extensively investigated and no reports on omentin and CORS-26 do exist. Methods Therefore the plasma levels of these proteins before and 120 min after an oral glucose load were analyzed in 20 highly-insulin sensitive, young adults by ELISA or immunoblot. Results Circulating leptin was reduced 2 h after glucose uptake whereas adiponectin and resistin levels are not changed. Distribution of adiponectin and CORS-26 isoforms were similar before and after glucose ingestion. Omentin is highly abundant in plasma and immunoblot analysis revealed no alterations when plasma levels before and 2 h after glucose intake were compared. Conclusion Taken together our data indicate that only leptin is reduced by glucose uptake in insulin-sensitive probands whereas adiponectin and resistin are not altered. CORS-26 was demonstrated for the first time to circulate as high molecular weight form in plasma and like omentin was not influenced by oral glucose load. Omentin was shown to enhance insulin-stimulated glucose uptake but systemic levels are not correlated to postprandial blood glucose.

  4. 1981-1982 Evaluation Report of The University of Southern California School of Medicine Med-Cor Program: One of the Predominantly Hispanic, Black, Asian and Other Non-Anglo (PHBAO) Programs.

    Science.gov (United States)

    Wright, John

    Med-Cor is a program designed to improve the maturation, interest, and academic skill level of junior and senior high school students. The program is jointly sponsored by the University of Southern California School of Medicine and the Los Angeles Unified School District. Students are tutored with the expectation that their academic skills will…

  5. A construção da nação arco-íris: problematizando o quesito raça/cor (1936-1960)

    OpenAIRE

    Nascimento, Alessandra Santos [UNESP

    2005-01-01

    A presente dissertação é resultado de um estudo acerca do referencial teórico que influenciou a construção e consolidação do quesito raça/cor do Instituto Brasileiro de Geografia e Estatística, no período de 1936 a 1960. O caminho por nós escolhido para compreender a construção de tal quesito foi o diálogo entre a hermenêutica (RICOEUR, 1969) e a análise de conteúdo (BARDIN, 1977), no processo de interpretação dos artigos da Revista Brasileira de Geografia e da Revista Brasileira de Estatísti...

  6. Transformações ocorridas na vida de atingidos pela barragem de Irapé: o caso do Quilombo de Porto Corís

    Directory of Open Access Journals (Sweden)

    Gilmar Fialho de Freitas Gilmar

    2015-12-01

    Full Text Available Este artigo tem por objetivo apontar as transformações ocorridas a partir da trajetória de vida dos reassentados da Usina Hidrelétrica de Irapé no Vale do Jequitinhonha-MG. O estudo foi realizado na Comunidade Remanescente de Quilombo de Porto Corís em Leme do Prado – MG. Para isso, utilizou-se como método principal o estudo de caso, com informações coletadas através de documentos escritos, entrevistas, observação participante e participação em reuniões das Associações de Moradores que formam os reassentamentos. Através deste estudo, constata-se que a trajetória de vida dessas populações reassentadas em Irapé é marcada pela inevitabilidade que um processo de reassentamento forçado possui.

  7. Termoterapia transpupilar como opção terapêutica para hemangioma circunscrito de coróide: relato de caso

    Directory of Open Access Journals (Sweden)

    Roizenblatt Jaime

    2002-01-01

    Full Text Available Os autores descrevem um caso de hemangioma circunscrito de coróide, com descolamento de retina associado, tratado por meio de termoterapia transpupilar com laser de diodo. Os parâmetros utilizados foram: 900 mW, mira de 4,2 mm, tempo de 3 minutos, lente QuadrAspheric (Volkâ com fator de magnificação de 1,97. Um mês após o tratamento ocorreu redução significativa do hemangioma, com recuperação integral da visão deste olho. São feitas considerações a respeito do método, o qual mostra-se promissor no tratamento destes tumores vasculares.

  8. Resolution of cor pulmonale after medical management in a patient with cblC-type methylmalonic aciduria and homocystinuria: a case report

    Science.gov (United States)

    Kirmse, Brian; Wasserstein, Melissa P; Diaz, George; Srivastava, Shubhika

    2009-01-01

    We describe a 3-year-old Hispanic male with cblC-type methylmalonic aciduria and homocystinuria who presented to the emergency department with progressive tachypnea, vomiting, and edema secondary to pulmonary embolism and cor pulmonale. With aggressive medical management, there was complete resolution of right heart failure and pulmonary hypertension after 3 months. Pulmonary embolism is rare in the pediatric population. Children with cblC-type methylmalonic aciduria and homocystinuria may be at increased risk for thrombus formation and pulmonary embolism due to chronic hyperhomocystinemia, a risk factor for thrombus formation in the adult population. Aspirin therapy may be indicated in children with inborn errors of metabolism that predispose to hyperhomocystinemia. PMID:19830091

  9. Catalog and comparison of societal preferences (utilities) for lung cancer health states: results from the Cancer Care Outcomes Research and Surveillance (CanCORS) study.

    Science.gov (United States)

    Tramontano, Angela C; Schrag, Deborah L; Malin, Jennifer K; Miller, Melecia C; Weeks, Jane C; Swan, J Shannon; McMahon, Pamela M

    2015-04-01

    The EQ-5D and SF-6D are 2 health-related quality-of-life indexes that provide preference-weighted measures for use in cost-effectiveness analyses. The National Cancer Institute's Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium included the EQ-5D and SF-12v2 in their survey of newly diagnosed lung cancer patients. Utilities were calculated from patient-provided scores for each domain of the EQ-5D or the SF-6D. Utilities were calculated for categories of cancer type, stage, and treatment. There were 5015 enrolled lung cancer patients with a baseline survey in CanCORS; 2396 (47.8%) completed the EQ-5D, and 2344 (46.7%) also completed the SF-12v2. The mean (standard deviation) utility from the EQ-5D was 0.78 (0.18), and from the SF-6D (derived from SF-12v2) was 0.68 (0.14). The EQ-5D demonstrated a ceiling effect, with 20% of patients reporting perfect scores, translating to a utility of 1.0. No substantial SF-6D floor effects were noted. Utilities increased with age and decreased with stage and comorbidities. Patient-reported (EQ-5D) visual analog scale scores for health status had a moderate (r = 0.48, p catalog of community-weighted utilities applicable to societal-perspective cost-effectiveness analyses of lung cancer interventions and compared utilities based on the EQ-5D and SF-6D. Potential users of these scores should be aware of the limitations and think carefully about their use in specific studies. © The Author(s) 2015.

  10. The maize CorA/MRS2/MGT-type Mg transporter, ZmMGT10, responses to magnesium deficiency and confers low magnesium tolerance in transgenic Arabidopsis.

    Science.gov (United States)

    Li, Hongyou; Wang, Ning; Ding, Jianzhou; Liu, Chan; Du, Hanmei; Huang, Kaifeng; Cao, Moju; Lu, Yanli; Gao, Shibin; Zhang, Suzhi

    2017-10-01

    ZmMGT10 was specifically expressed in maize roots and induced by a deficiency of magnesium. Overexpression of ZmMGT10 restored growth deficiency of the Salmonella typhimurium MM281 strain and enhanced the tolerance in Arabidopsis to stress induced by low magnesium levels by increasing uptake of Mg 2+ via roots. CorA/MRS2/MGT-type Mg 2+ transporters play a significant role in maintaining magnesium (Mg) homeostasis in plants. Although the maize CorA/MRS2/MGT family comprises of 12 members, currently no member has been functionally characterized. Here, we report the isolation and functional characterization of ZmMGT10 from the maize MRS2/MGT gene family. ZmMGT10 has a typical structure feature which includes two conserved TMs near the C-terminal end and an altered AMN tripeptide motif. The high sequence similarity and close phylogenetic relationship indicates that ZmMGT10 is probably the counterpart of Arabidopsis AtMGT6. The complementation of the Salmonella typhimurium mutated MM281 strain indicates that ZmMGT10 possesses the ability to transport Mg 2+ . ZmMGT10 was specifically expressed in the plant roots and it can be stimulated by a deficiency of Mg. Transgenic Arabidopsis plants which overexpressed ZmMGT10 grew more vigorously than wild-type plants under low Mg conditions, exhibited by longer root length, higher plant fresh weight and chlorophyll content, suggesting ZmMGT10 was essential for plant growth and development under low Mg conditions. Further investigations found that high accumulation of Mg 2+ occurred in transgenic plants attributed to improved Mg 2+ uptake and thereby enhanced tolerance to Mg deficiency. Results from this investigation illustrate that ZmMGT10 is a Mg transporter of maize which can enhance the tolerance to Mg deficient conditions by improving Mg 2+ uptake in the transgenic plants of Arabidopsis.

  11. CorRECTreatment: a web-based decision support tool for rectal cancer treatment that uses the analytic hierarchy process and decision tree.

    Science.gov (United States)

    Suner, A; Karakülah, G; Dicle, O; Sökmen, S; Çelikoğlu, C C

    2015-01-01

    The selection of appropriate rectal cancer treatment is a complex multi-criteria decision making process, in which clinical decision support systems might be used to assist and enrich physicians' decision making. The objective of the study was to develop a web-based clinical decision support tool for physicians in the selection of potentially beneficial treatment options for patients with rectal cancer. The updated decision model contained 8 and 10 criteria in the first and second steps respectively. The decision support model, developed in our previous study by combining the Analytic Hierarchy Process (AHP) method which determines the priority of criteria and decision tree that formed using these priorities, was updated and applied to 388 patients data collected retrospectively. Later, a web-based decision support tool named corRECTreatment was developed. The compatibility of the treatment recommendations by the expert opinion and the decision support tool was examined for its consistency. Two surgeons were requested to recommend a treatment and an overall survival value for the treatment among 20 different cases that we selected and turned into a scenario among the most common and rare treatment options in the patient data set. In the AHP analyses of the criteria, it was found that the matrices, generated for both decision steps, were consistent (consistency ratiodecisions of experts, the consistency value for the most frequent cases was found to be 80% for the first decision step and 100% for the second decision step. Similarly, for rare cases consistency was 50% for the first decision step and 80% for the second decision step. The decision model and corRECTreatment, developed by applying these on real patient data, are expected to provide potential users with decision support in rectal cancer treatment processes and facilitate them in making projections about treatment options.

  12. Paracoccidioidomicose pulmonar agressiva, endotraqueíte estenosante e cor-pulmonale subagudo: descrição de um caso

    Directory of Open Access Journals (Sweden)

    E. P. Campos

    1986-06-01

    Full Text Available A paracoccidioidomicose (Pbmicose atinge os pulmões pela via inalatória, onde se estabelece o complexo primário semelhante ao da tuberculose. A traquéia comprometida pela via tubohemolinfática desenvolveria reação inflamatória em processo granulomatoso levando à obstrução estenosante com asíixia. Acompanhou-se um doente, masculino, 32 anos, branco, natural de Sarutaiá (SP, lavrador, que há 8 meses desenvolveu tosse expectorativa branco-amarelada, diária, sem fatores de melhora ou piora e dispnéia inicial discreta. Há 4 meses, anorexia, fraqueza e astenia. Há 1 mês a dispneia se agravou. Perdeu 15 kg. Tabagista e etilista há 16 anos. Exame físico revelou: PA — 10/7 mmHg, FR = 28 bpm, peso 31 kg, hipocratismo digital e hipotrofia muscular Tórax enfisematoso e síndrome obstrutivo aos testes de função pulmonar. Coração: P2 desdobrada e hiperfonética. Hepatesplenomegalia. Desenvolveu cor-pulmonale e insuficiência adrenal à internação, evoluindo após 45 dias para óbito em insuficiência respiratória aguda asfixiante, apesar da terapia antifúngica ter sido completa. A literatura médica revista não mostrou registro de caso semelhante de cor-pulmonale e insuficiência adrenal de evolução subaguda.

  13. La "ville décor" : accueil de tournages de films et mise en place d'une nouvelle esthétique urbaine

    Directory of Open Access Journals (Sweden)

    Maria Gravari-Barbas

    1999-05-01

    Full Text Available Depuis quelques années, nombre de villes et de régions françaises s´organisent pour accueillir des équipes de tournage de films. Afin d’aider les régisseurs des films dans leur choix de décors urbains, la ville est découpée par les responsables locaux en "morceaux choisis", présentés sur des nouveaux supports de présentation (carnets de repérage, Cd-Roms, SIG. Notre hypothèse est double : d´une part les supports de communication cinématographique à la fois créent et véhiculent une nouvelle esthétique urbaine. Celle-ci n´obéit pas aux codes esthétiques couramment admis dans les documents de communication urbaine. Il ne s´agit pas d´une esthétique de "conformité", telle que celle qui est véhiculée par les plaquettes de marketing territorial, mais d´une anti-esthétique qui exploite l´élément inédit, trouble, peu courant et semble jouer sur un registre d´hyperréalité. D´autre part, les responsables locaux ont de plus en plus tendance à exploiter et à mettre en scène cette esthétique cinématographique : ainsi, il cherchent à montrer la ville telle qu´elle a été saisie par la caméra. Le regard cinématographique apporte en effet une plus-value culturelle et médiatique à des lieux qui n´avaient pas a priori une qualité esthétique affirmée. Nous parlons de la "ville-décor" car nous estimons que les initiatives prises par les acteurs locaux pour l´accueil des tournages, consistent à transformer potentiellement la ville en décor géant. Les documents créés à cette occasion, carnets de repérages, Cédéroms ou autres, "découpent" la ville en séquences photographiques, légendées, caractérisées, commentées. Dans le contexte actuel où, grâce au cinéma, la télévision, l´internet, l’expérience de la ville devient plus virtuelle que réelle, la question de l´image et de l’esthétique urbaines créée par les médias visuels, revêt, nous semble-t-il, d´une importance nouvelle.

  14. Microdureza de resinas em função da cor e luz halógena Microhardness of resins as a function of color and halogen light

    Directory of Open Access Journals (Sweden)

    Fábio Martins

    2002-09-01

    Full Text Available O objetivo desse trabalho foi avaliar a influência da intensidade da luz e cor de uma resina composta no grau de dureza Knoop. Corpos-de-prova foram confeccionados utilizando-se matrizes de poliéster envoltas por um anel de cobre, contendo uma cavidade padronizada de 6 mm de diâmetro por 2 mm de espessura. Estas cavidades foram preenchidas com resina composta selecionada, Fill Magic - Vigodent, com as cores A3, B3, C3, D3 e I, fotopolimerizadas através de um fotopolimerizador Elipar, calibrado para produzir 3 intensidades de luz diferentes: 450 mW/cm², 800 mW/cm² e uma intensidade de luz crescente de 100 a 800 mW/cm². Foram confeccionados 90 corpos-de-prova em que o tempo de exposição da resina à luz halógena foi de 40 s. As amostras foram armazenadas em tubos de ensaio com água destilada a 37 ± 1ºC. Após este período, foram realizados os testes de dureza Knoop na região de superfície e fundo. Os resultados mostraram que houve diferença estatística em relação a intensidade de luz, entretanto em relação a cor, não houve diferença estatística. Os autores concluíram que a cor do compósito não influencia a dureza Knoop e que a intensidade progressiva promoveu os melhores resultados de dureza Knoop.The aim of this study was to evaluate the influence of light intensity and the influence of the color of a composite resin on Knoop hardness. Samples were confected utilizing polyester matrices with 6 mm of diameter and 2 mm of depth. The matrices were filled with composite resin (Fill Magic - Vigodent, colors A3, B3, C3, D3 and I, and light-cured by means of an Elipar light-curing unit in three different light intensities: 450 mW/cm2, 800 mW/cm² and an increasing intensity setup of 100 mW/cm² to 800 mW/cm². Ninety test specimens were confected, with the standard curing time of 40 seconds. The specimens were stored at 37 ± 1ºC and immersed in distillate water. The Knoop test was carried out in superficial and deep areas

  15. Using residual stacking to mitigate site-specific errors in order to improve the quality of GNSS-based coordinate time series of CORS

    Science.gov (United States)

    Knöpfler, Andreas; Mayer, Michael; Heck, Bernhard

    2014-05-01

    Within the last decades, positioning using GNSS (Global Navigation Satellite Systems; e.g., GPS) has become a standard tool in many (geo-) sciences. The positioning methods Precise Point Positioning and differential point positioning based on carrier phase observations have been developed for a broad variety of applications with different demands for example on accuracy. In high precision applications, a lot of effort was invested to mitigate different error sources: the products for satellite orbits and satellite clocks were improved; the misbehaviour of satellite and receiver antennas compared to an ideal antenna is modelled by calibration values on absolute level, the modelling of the ionosphere and the troposphere is updated year by year. Therefore, within processing of data of CORS (continuously operating reference sites), equipped with geodetic hardware using a sophisticated strategy, the latest products and models nowadays enable positioning accuracies at low mm level. Despite the considerable improvements that have been achieved within GNSS data processing, a generally valid multipath model is still lacking. Therefore, site specific multipath still represents a major error source in precise GNSS positioning. Furthermore, the calibration information of receiving GNSS antennas, which is for instance derived by a robot or chamber calibration, is valid strictly speaking only for the location of the calibration. The calibrated antenna can show a slightly different behaviour at the CORS due to near field multipath effects. One very promising strategy to mitigate multipath effects as well as imperfectly calibrated receiver antennas is to stack observation residuals of several days, thereby, multipath-loaded observation residuals are analysed for example with respect to signal direction, to find and reduce systematic constituents. This presentation will give a short overview about existing stacking approaches. In addition, first results of the stacking approach

  16. Efeitos da radiação gama na cor, capacidade antioxidante e perfil de ácidos graxos em amendoim (Arachis hypogaea L.

    Directory of Open Access Journals (Sweden)

    Adriano Costa de Camargo

    2011-03-01

    Full Text Available A irradiação gama é eficiente para eliminar a contaminação fúngica em grãos de amendoim. Este apresenta proteínas de alto valor biológico, minerais, vitaminas E, complexo B e alta concentração de lipídios. Este trabalho teve como objetivo avaliar o efeito da aplicação de radiações gama na cor, fenólicos totais, atividade antioxidante e perfil de ácidos graxos em amendoim (Arachis hypogaea L.. Os cultivares IAC-Tatu ST e IAC-Runner 886 foram submetidos a radiações gama com doses de 5,0; 7,5; 10,0; e 15,0 kGy e armazenados em temperatura ambiente. Não foram verificadas diferenças significativas na cor dos amendoins IAC-Tatu ST. Diferenças significativas foram detectadas para a luminosidade e o Croma do IAC-Runner 886. Os fenólicos totais diferiram significativamente entre o controle com 33,27 mg.g-1 e o tratamento com 10,0 kGy com 58,60 mg.g-1 no IAC-Tatu ST, neste parâmetro não foram observadas diferenças significativas no IAC-Runner 886, cujo controle foi 51,59 mg.g-1. Para atividade antioxidante não foi verificada diferença significativa com a dose de 10,0 kGy, recomendada para eliminação fúngica de amendoim. Na dose de 10,0 kGy, verificou-se a diminuição de ácidos graxos saturados, o aumento dos insaturados e o aumento de ácido linoleico. A relação oleico/linoleico diminuiu, justificando novos estudos correlacionando armazenamento e estabilidade oxidativa.

  17. Laminados biodegradáveis de blendas de amido de mandioca e poli(vinil álcool: efeito da formulação sobre a cor e opacidade

    Directory of Open Access Journals (Sweden)

    Juliano Zanela

    2015-06-01

    Full Text Available ResumoForam produzidos 12 laminados com diferentes proporções de amido de mandioca, poli(vinil álcool (PVA e glicerol por extrusão usando um planejamento de mistura. A opacidade dos materiais variou entre 31 e 56%, e a concentração de PVA e a interação entre as concentrações de amido e PVA foram os principais responsáveis pelo aumento da opacidade. A diferença de cor (ΔE* variou entre 20-30, sendo a concentração de amido o principal responsável pelo aumento da diferença de cor, por promover uma coloração mais amarelada nos laminados.

  18. Acute pulmonary embolism: prediction of cor pulmonale and short-term patient survival from assessment of cardiac dimensions in routine multidetector-row CT; Mehrschicht-Spiral-CT bei vermuteter und inzidenteller akuter Lungenembolie: prognostischer Wert morpholoqischer Herzparameter

    Energy Technology Data Exchange (ETDEWEB)

    Engeike, C. [Radiologie, Klinikum rechts der Isar der Technischen Univ. Muenchen (Germany); Rummeny, E.; Marten, K. [Inst. fuer Roentgendiagnostik, Klinikum rechts der Isar der Technischen Univ. Muenchen (Germany)

    2006-10-15

    Purpose: evaluation of the prognostic value of morphological cardiac parameters in patients with suspected and incidental acute pulmonary embolism (PE) using multidetector-row chest CT (MSCT). Materials and methods: 2335 consecutive MSCT scans were evaluated for the presence of PE. The arterial enhancement and analysability of pulmonary arteries and the heart were assessed as parameters of the scan quality. The diastolic right and left ventricular short axes (RV{sub D}, LV{sub D}) and the interventricular septal deviation (ISD) were measured in all PE-positive patients and the echocardiography reports were reviewed. The clinical data assessment included cardio-respiratory and other co-morbidities, systemic anticoagulant therapy (ACT), and the 30-day outcome. Predictors of acute cor pulmonale and the short-term outcome were calculated by univariate and multivariate logistic regressions including odds ratios (OR) and ROC analyses using positive (PPV) and negative predictive values (NPV). Results: 90 patients with acute PE were included (36 with clinically suspected PE, 54 with incidental PE). 26 patients had cardio-respiratory co-morbidities. Four patients underwent systemic thrombolysis, 43 underwent anticoagulation in therapeutic doses, 19 underwent anticoagulation in prophylactic doses, and 24 patients did not undergo ACT. 15 of 41 patients had echocardiographic evidence of acute cor pulmonale. 8 patients died within 30 days. The RV{sub D} was the best independent predictor of acute cor pulmonale (p = 0,002, OR = 9.16, PPV = 0.68, NPV=1 at 4.49 cm cut off) and short-term outcome (p= 0,0005, OR = 2.82, PPV = 0.23, NPV = 0.98 at 4.75 cm cut off). The RV{sub D}/LV{sub D} ratio had a PPV of 0.85 for cor pulmonale. (orig.)

  19. ANALISA PERBANDINGAN KETELITIAN PENENTUAN POSISI DENGAN GPS RTK-NTRIP DENGAN BASE GPS CORS BIG DARI BERBAGAI MACAM MOBILE PROVIDER DIDASARKAN PADA PERGESERAN LINEAR (STUDI KASUS: SURABAYA

    Directory of Open Access Journals (Sweden)

    Atika Sari

    2015-02-01

    Full Text Available Penentuan posisi dalam pemetaan menggunakan penginderaan jauh dan foto udara memerlukan pengamatan GPS geodetik sebagai titik kontrol yang memilki ketelitian tinggi. Sistem koreksi data penentuan posisinya diperoleh dari transmisi data dari stasiun base ke receiver. Dalam perkembangan sekarang ini metode pengukuran RTK telah menggunakan metode NTRIP (Networked Transport of RTCM via Internet Protocol sebagai metode transmisi koreksi data dengan menggunakan intenet sehingga pengukuran tersebut masih bisa dilakukan dengan jarak yang lebih jauh dari base-nya. Pada metode NTRIP ini menggunakan metode pengiriman koreksi data GNSS melalui jaringan internet. Pengembangan sistem dengan fasilitas akses internet mobile melalui general packet radio service (GPRS dan global system for mobile (GSM, menyediakan metode cepat dan handal untuk mendistribusikan baris data GPS atau koreksi diferensial real-time (DGPS / RTK ke penerima GPS di daerah manapun yang berada di bawah jangkauan jaringan telepon seluler. Sehingga untuk mengetahui provider yang sesuai digunakan dalam wilayah surabaya dalam menggunakan metode RTK NTRIP maka dilakukanlah penelitian ini. Dari hasil pengamatan dari pengukuran dengan menggunakan  metode RTK-NTRIP dengan base GPS CORS BIG didapat nilai rata-rata dari masing-masing provider sekitar < 4 m.

  20. Guilhem de Saint Gregori, "Ben grans avolesa intra" (BdT 233.2; Bartolomeo Zorzi, "En tal dezir mos cors intra" (BdT 74.4

    Directory of Open Access Journals (Sweden)

    Alessandro Bampa

    2014-02-01

    Full Text Available This paper provides a commentary and translation of two contrafacta of Arnaut Daniel’s sestina: Guilhem de Saint Gregori’s "Ben gran avolesa intra" and Bartolomeo Zorzi’s "En tal dezir mos cors intra". For the first song, I will highlight the new contexts and meanings given to Arnaut’s images (which are taken from his sestina and other poems within Guilhem’s invective against Aimers II of Poitiers, in order to evaluate its literary qualities and innovations. Through lexical analysis, this paper will reveal the strong connection between Zorzi’s and Guilhem’s songs. In particular, the paper analyses specifically their common theme of Hell, suggesting Bartolomeo’s text is most likely an answer to Arnaut’s sestina, which clearly expresses a desire of sensual pleasure. The study pays particular attention to the relation between sexual love and the matter of eternal damnation: Zorzi attacks Arnaut’s ferm voler, advancing his argument by evoking Chrétien de Troyes’ "Perceval" (references to which are spread throughout the text, and not only in l. 18 and through his constant stress on the duties towards one’s family.

  1. Educação, pobreza e emprego: uma análise a partir das categorias escolaridade, gênero e cor

    Directory of Open Access Journals (Sweden)

    Ramon de Oliveira

    2013-05-01

    Full Text Available http://dx.doi.org/10.5007/2175-795X.2013v31n2p687 A partir da crítica aos pressupostos da Teoria do Capital Humano, objetiva-se mostrar que as variáveis sexo, cor e escolaridade têm pesos diferentes na defi nição da entrada e permanência dos trabalhadores no mercado de trabalho, bem como têm repercussão direta nas condições da ocupação, quando são levados em conta o salário e os direitos trabalhistas. Analisando informações do mercado de trabalho, conclui-se que a desigualdade estabelecida no trato de negros e mulheres inibe a infl uência dos ganhos que possam ser decorrentes do aumento de escolarização, principalmente entre as mulheres negras e que, por conseguinte, a articulação direta entre escolarização e diminuição do quadro de pobreza não encontra sustentação empírica.

  2. Choroid plexus papilloma and Aicardi syndrome: case report Papiloma do plexo coróideo e síndrome de Aicardi: relato de caso

    Directory of Open Access Journals (Sweden)

    Geraldo Pianetti Filho

    2002-12-01

    Full Text Available A case of Aicardi syndrome associated with a choroid plexus papilloma of the third and both lateral ventricles in a 15 months old baby girl is repported. The tumor was completely removed via three craniotomies. Reports of the literature with the association of choroid plexus papilloma and Aicardi syndrome are rare. We suggest that children diagnosed with Aicardi syndrome should routinely undergo imaging studies of the brain, such as computed tomography or magnetic resonance.Relatamos o caso de uma criança com 15 meses de idade, portadora da síndrome de Aicardi associada a tumores nos ventrículos laterais e terceiro ventrículo (papilomas que foram retirados cirurgicamente através de três craniotomias. A ocorrência de papiloma do plexo coróideo associada à sindrome de Aicardi é raramente descrita na literatura. Sugerimos que as crianças portadoras da síndrome de Aicardi sejam rotineiramente submetidas a estudo radiológico do encéfalo através da tomografia computadorizada ou ressonância nuclear.

  3. [Change in serum basic fibroblast growth factor level and its relationship to pulmonary arterial pressure in patients with acute exacerbation of chronic cor pulmonale on plateau].

    Science.gov (United States)

    Yang, Sheng-yue; Shen, Jun-li; Feng, En-zhi; Xu, Jun; Huang, Ning-xia; Zhao, Li-hong; Wu, Xue-mei; Zhang, Dong-tian; Zhang, Ying

    2006-12-01

    To assess the role of serum basic fibroblast growth factor (bFGF) in the development of hypoxic pulmonary hypertension in the patients with chronic cor pulmonale on highland (HACCP). The levels of bFGF in serum of 38 patients with HACCP in the acute exacerbation stage, 30 patients with chronic obstructive pulmonary disease (COPD) in the remission stage and 30 normal control subjects were measured by sandwich enzyme-linked immunoadsorbent assay (ELISA). The mean pulmonary arterial pressure (MPAP) was measured by echocardiography. The partial pressure of oxygen in artery blood (PaO(2)) was measured by blood gas analyzer. The level of serum bFGF [(87.54+/-12.15) ng/L] and MPAP [(45.86+/-5.63)mm Hg (1 mm Hg=0.133 kPa)] in the patients with HACCP were significantly higher than those in the patients with COPD [(55.72+/-9.08) ng/L, (22.95+/-2.56)mm Hg, respectively, both Pcor pulmonale group r=0.788, Pcor pulmonale group r=-0.735, P<0.01; COPD group r=-0.587, P<0.01)). The level of serum bFGF in patients with HACCP is significantly increased; it may play an important role in the process of sustained hypoxic pulmonary hypertension in patients with HACCP.

  4. The System of Neutrophil Elastase and the Plasma Level of MMP-7 in Children with Pulmonary Arterial Hypertension and Chronic Cor Pulmonale

    Directory of Open Access Journals (Sweden)

    Еlena M. Vasilyeva

    2014-03-01

    Full Text Available A significant increase in the activity of neutrophil elastase (NE and anti-NE-protection in the plasma were detected in children having bronchopulmonary dysplasia (BPD complicated by pulmonary arterial hypertension (PAH and chronic cor pulmonale (CCP. The changes revealed were more pronounced in patients with CCP. The plasma concentration of the NE was slightly reduced, which was probably associated with the activation of anti-NE and an increase in the α1-antitrypsin level. A gradual increase was noted in the plasma level of the matrix metalloproteinase-7 (MMP-7 in patients with an increase in the severity of the condition. In patients with cystic fibrosis (with and without CCP, the pronounced increase in the MMP-7 level was observed. In patients with cystic fibrosis (CF, even without the additional complication with PAH and CCP, the MMP-7 level was significantly higher than in those with congenital broncho-pulmonary malformations (CBPM. The difference was increased in those patients with PAH and reached a maximum in those with CCP.

  5. Incidence Proportion of Acute Cor Pulmonale in Patients with Acute Respiratory Distress Syndrome Subjected to Lung Protective Ventilation: A Systematic Review and Meta-analysis.

    Science.gov (United States)

    Das, Saurabh Kumar; Choupoo, Nang Sujali; Saikia, Priyam; Lahkar, Amitabh

    2017-06-01

    Reported incidence of acute cor pulmonale (ACP) in patients with acute respiratory distress syndrome (ARDS) varies from 10% to 84%, despite being subjected to lung protective ventilation according to the current guidelines. The objective of this review is to find pooled cumulative incidence of ACP in patients with ARDS undergoing lung protective ventilation. We searched MEDLINE, EMBASE, Cochrane Library, KoreaMed, LILACS, and WHO Clinical Trial Registry. Cross-sectional or cohort studies were included if they reported or provided data that could be used to calculate the incidence proportion of ACP. Inverse variance heterogeneity (IVhet) and random effect model were used for the main outcome and measures. We included 16 studies encompassing 1661 patients. The cumulative incidence of ACP using IVhet analysis was 23% (95% confidence interval [CI] = 18%-28%) over 3 days of lung protective ventilation. Random effect analysis of 7 studies (1250 patients) revealed pooled odd ratio of mortality of 1.16 (95% CI = 0.80-1.67, P = 0.44) due to ACP. Patients with ARDS have a 23% risk of developing ACP with lung protective ventilation. Findings of this review indicate the need of updating existing guidelines for ventilating ARDS patients to incorporate right ventricle protective strategy.

  6. Prevalence and prognostic value of acute cor pulmonale and patent foramen ovale in ventilated patients with early acute respiratory distress syndrome: a multicenter study.

    Science.gov (United States)

    Lhéritier, Gwenaëlle; Legras, Annick; Caille, Agnès; Lherm, Thierry; Mathonnet, Armelle; Frat, Jean-Pierre; Courte, Anne; Martin-Lefèvre, Laurent; Gouëllo, Jean-Paul; Amiel, Jean-Bernard; Garot, Denis; Vignon, Philippe

    2013-10-01

    We sought to determine the prevalence of and factors associated with acute cor pulmonale (ACP) and patent foramen ovale (PFO) at the early phase of acute respiratory distress syndrome (ARDS), and to assess their relation with mortality. In this prospective multicenter study, 200 patients submitted to protective ventilation for early moderate to severe ARDS [PaO₂/F(I)O₂: 115 ± 39 with F(I)O₂: 1; positive end-expiratory pressure (PEEP): 10.6 ± 3.1 cmH2O] underwent transthoracic (TTE) and transesophageal echocardiography (TEE) 60 mmHg was strongly associated with ACP [odds ratio (OR) 3.70; 95% CI 1.32-10.38; p = 0.01]. No factor was independently associated with PFO, with only a trend for age (OR 2.07; 95% CI 0.91-4.72; p = 0.08). Twenty-eight-day mortality was 23%. Plateau pressure (OR 1.15; 95% CI 1.05-1.26; p < 0.01) and air leaks (OR 5.48; 95% CI 1.30-22.99; p = 0.02), but neither ACP nor PFO, were independently associated with outcome. TEE screening allowed identification of ACP in one-fourth of patients submitted to protective ventilation for early moderate to severe ARDS. PFO shunting was less frequent and never large or extensive. ACP and PFO were not related to outcome.

  7. Données bibliographiques sur l'élevage des jeunes stades et la biologie des corégones

    Directory of Open Access Journals (Sweden)

    MACK A.

    1984-01-01

    Full Text Available Une revue sommaire de la bibliographie portant sur quelques aspects de la biologie et de l'élevage du corégone fait l'objet de cet article Les problèmes de systématique sont brièvement exposés. La présentation de la biologie de l'espèce (gamétogenèse, fécondité, embryogenèse, croissance, exigences de l'environnement, etc. est développée en relation avec les problèmes d'élevage posés par ces espèces : stockage des géniteurs, reproduction, insémination artificielle, incubation, élevage larvaire dans diverses conditions, élevage des estivaux, etc. Les possibilités d'utiliser ces espèces pour l'élevage en étang ou pour le pacage lacustre sont examinées.

  8. Desigualdade educacional na ocorrência de obesidade abdominal por gênero e cor/raça: Estudo Pró-Saúde, 1999-2001 e 2011-2012

    Directory of Open Access Journals (Sweden)

    Ronaldo Fernandes Santos Alves

    2016-01-01

    Full Text Available Resumo Análise de dados seccionais do Estudo Pró-Saúde (1999-2001 e 2011-2012 revelou importante diferença de gênero e cor/raça na magnitude e variação temporal da desigualdade educacional na obesidade abdominal. Probabilidade de estar obeso foi gradativamente maior em mulheres (independentemente de cor/raça e homens (pardos/pretos menos escolarizados. Tais gradientes foram quantificados pelo índice relativo de desigualdade (IRD. Ao longo da década, observou-se redução da desigualdade em mulheres pardas/pretas (ΔIRD: 0,5; IC95%: 0,2-1,1, subjacente ao relativo aumento da prevalência de obesidade abdominal entre as mais escolarizadas. Houve estabilidade do IRD em mulheres brancas e homens pardos/pretos, indicando crescimento similar da prevalência de obesidade abdominal nos subgrupos educacionais. Associação da escolaridade com a ocorrência de obesidade abdominal sofreu interação múltipla de fatores sociodemográficos. Nossos resultados encorajam a estratificação conjunta por gênero e cor/raça no estudo das desigualdades socioeconômicas na ocorrência da obesidade abdominal.

  9. Color change using HSB color system of dental resin composites immersed in different common Amazon region beverages Alteração de cor de resinas compostas imersas em diferentes bebidas comuns da região Amazônica, utilizando o sistema de cor HSB

    Directory of Open Access Journals (Sweden)

    Débora da Costa e Silva

    2009-01-01

    Full Text Available The purpose of this study is to evaluate in vitro the color stability of composite resins when exposed to beverages with high coloring contents from the Amazon region. 240 samples from four different composite brands (Natural Look, Z350, 4Seasons and Opallis of hue A3 were fabricated using an acrylic matrix. The samples were stored in distilled water at 37ºC for 24 hours. The initial color (T0 was registered using a Canon EOS Rebel XTi 10 mp camera, and then the samples were divided into four groups (n=15: G1 (coffee, G2 (açaí juice, G3 (energetic guaraná and G4 (control - distilled water. The samples were exposed to solutions of DES (6hs and RE (18hs and placed in a double boiler under constant agitation, at 37ºC for 30 days. The samples were immersed in the coloring solutions for 15 minutes daily. After 7, 15 and 30 days, new photographic registers were made (T1, T2 and T3. The images were analyzed using Corel PHOTO-PAINT 12 software to identify the colors through the HSB system. The Kruskal-Wallis and t tests (pEste estudo propôs avaliar in vitro a estabilidade de cor de alguns compósitos quando expostos a bebidas da Região Amazônica com alto teor de corante. Foram confeccionados 240 corpos de prova (CP de quatro resinas (Natural Look, Z350, 4Seasons e Opallis no matiz A3 utilizando uma matriz de acrílico. As amostras foram armazenadas em água deionizada a 37ºC por 24 horas. A cor inicial das resinas (T0 foi registrada utilizando a máquina Canon EOS Rebel XTi 10Mp, e em seguida os CP foram divididos em 4 grupos (n=15: G1 (café, G2 (suco de açaí, G3 (guaraná energético e G4 (controle - água destilada. Os CP foram submetidos às soluções DES (6hs e RE (18hs e colocados em banho-maria, sob constante agitação, à temperatura de 37ºC durante 30 dias. Diariamente os corpos de prova foram imersos nas soluções corantes durante 15 minutos. Após 7, 15 e 30 dias realizaram-se novos registros fotográficos (T1, T2 e T3. As

  10. Cor, betacaroteno e colesterol em gema de ovos obtidos de poedeiras que receberam diferentes dietas Color, beta-caroten and cholesterol in yolks of eggs by different diets of laying hens

    Directory of Open Access Journals (Sweden)

    Luciana Marino e Biscaro

    2006-12-01

    Full Text Available O ovo é um alimento considerado nutricionalmente completo, e contém quantidade significativa de nutrientes. Para os consumidores, a qualidade deste alimento está relacionada com o prazo de validade do produto e com as características sensoriais, como cor da gema e da casca. Poucos estudos foram efetuados no Brasil sobre a utilização de agentes pigmentantes e seus efeitos sobre a coloração das gemas e proporção e qualidade química dos componentes do ovo. Com base nisso, objetivou-se com este trabalho relacionar diferentes dietas com cor, quantidade de betacaroteno e teor colesterol das gemas dos ovos. Foram coletados ovos de poedeiras que receberam 4 diferentes tipos de ração. A cor foi medida em colorímetro Minolta, o beta-caroteno separado em coluna e medido em espectrofotômetro e o colesterol extraído com clorofórmio e quantificado por método colorimétrico. Os resultados mostraram que não há relação entre a cor e aumento do teor de betacaroteno das gemas dos ovos, mas a alimentação alterou a cor da gema. O teor de colesterol foi diferente (pEgg is a nutritional complete food, and content significant quantity of nutrients. For the consumers, the food quality is related with validity date of product and with sensorial characteristics, like yolk color and hull. Few studies were done in Brazil about utilization of colorfull agents and theirs effects in yolk color and chemical quality of egg compounds. The objective of this research was related different feeds with the color, beta-carotene and cholesterol amount of egg yolk. Eggs were caught of laying hens that received 4 feed types. The color measure was done by Minolta colorimeter, beta-carotene separated by column and spectrophotometer and cholesterol separated with chloroform and measured by colorimetric method. The results showed that there is not a relation between the color an increase of beta-carotene amount in the yolks, but feed altered the yolk color. Cholesterol

  11. Mortalidade infantil segundo raça/cor no Brasil: o que dizem os sistemas nacionais de informação? Infant mortality according to race/color in Brazil: what do the national databases say?

    Directory of Open Access Journals (Sweden)

    Andrey Moreira Cardoso

    2005-10-01

    Full Text Available O trabalho analisa a consistência dos Sistemas de Informações Sobre Mortalidade (SIM e Sobre Nascidos Vivos (SINASC como fontes de dados para a avaliação de desigualdades em raça/cor em saúde no Brasil. Foram obtidas taxas de mortalidade infantil (TMI segundo raça/cor informada nas declarações de óbitos e nascidos vivos (NV, para o país e grandes regiões, no período 1999/2002. Estimou-se também a TMI segundo raça/cor a partir da incorporação dos óbitos e NV com raça/cor não informada por dois critérios. Compararam-se as TMI obtidas no estudo com as TMI estimadas por métodos indiretos. Foram também calculadas razões das TMI entre categorias de raça/cor. Observou-se redução substancial do número de óbitos e NV com raça/cor não informada no período. Em 2002, a mortalidade infantil das crianças pretas superou em 30,0% e 80,0% a mortalidade infantil das brancas e em 40,0% e 80,0% a das pardas; o diferencial de mortalidade entre crianças indígenas e brancas ou pardas variou de 40,0% a 90,0% a mais para as primeiras. Espera-se que a melhoria dos registros do SIM e do SINASC permita um aprofundamento da discussão sobre desigualdades em saúde segundo raça, cor e etnia no país.This study analyzes the consistency of the Brazilian national information systems on mortality (SIM and live births (SINASC as data sources for evaluating health inequalities according to race/color. Infant mortality rates (IMRs were obtained according to race/color from death and live birth certificates for the country as a whole and its regions, for the years 1999-2002. The IMR was also estimated according to race/ color, based on the incorporation of deaths and live births with race/color not reported by two criteria. The study compared the IMRs obtained in the study with those estimated by indirect methods. The IMR ratios were also calculated between race/color categories. A substantial reduction was observed during the period in the

  12. Tratamento conservador ocular dos melanomas de coróide com braquiterapia utilizando placas de iodo-125 Conservative treatment of choroidal melanomas using iodine brachytherapy

    Directory of Open Access Journals (Sweden)

    Antônio Cássio Assis Pellizzon

    2004-08-01

    Full Text Available OBJETIVO: Avaliar, retrospectivamente, o resultado do tratamento conservador do melanoma de coróide, por meio de braquiterapia, usando placas episclerais de iodo-125 (modelo 6711, Amershan. MATERIAIS E MÉTODOS: Foram avaliados 49 pacientes portadores de melanoma de coróide tratados no Hospital do Câncer, São Paulo, SP, de março de 2001 a janeiro de 2003. Os seguintes parâmetros foram analisados e correlacionados ao controle local e sobrevida: sexo, idade, dimensões da lesão, tempo de tratamento e doses no ápice e base das lesões. RESULTADOS: Com diâmetro máximo da base do tumor de 17 mm e altura máxima de 12 mm, observamos que as doses na base do tumor variaram de 213 a 463 Gy (mediana de 347 Gy e no ápice, de 51 a 250 Gy (mediana de 91 Gy. As taxas de preservação ocular, sobrevida livre de doença e conservação ocular, atuariais em dois anos, foram de 96%, 93,5% e 96,3%, respectivamente. Através de análise univariada, o único fator prognóstico para controle local nesta análise foi a altura do tumor menor que 6 mm (p = 0,0348. CONCLUSÃO: A braquiterapia levou a uma taxa bastante satisfatória de controle local, confirmando que a altura do tumor é um dos fatores prognósticos importantes desse parâmetro.OBJECTIVE: To retrospectively evaluate the results of conservative therapy using episcleral iodine-125 (model 6711, Amershan plaque for brachytherapy of choroidal melanoma. MATERIALS AND METHODS: We evaluated 49 patients with choroidal melanoma treated at "Hospital do Câncer", São Paulo, Brazil, from March 2001 to January 2003. The following clinical parameters were analyzed and correlated with local control and survival rate: gender, age, lesion dimension, treatment duration, as well as doses in apex and base of the tumors. RESULTS: The maximum diameter and height of the base of the tumors treated were 17 mm and 12 mm, respectively. Doses at those points ranged from 213 to 463 Gy (median: 347 Gy and 51 to 250 Gy

  13. Acoustic analysis of prosody in Sydenham's chorea Análise acústica da prosódia em coréia de Sydenham

    Directory of Open Access Journals (Sweden)

    Patrícia M Oliveira

    2010-10-01

    Full Text Available There are few studies of language and speech in patients with Sydenham's chorea (SC. We have done an acoustic analysis of fundamental frequency (F0, duration and intensity of declarative and interrogative sentences made by 20 SC patients, 20 patients with rheumatic fever (RF without chorea, and compared them with 20 healthy age-matched controls (CO. Each group included 12 females. We found that there is no difference between the RF and CO groups in all studied parameters. Patients with SC, however, presented with a speech characterized by decreased F0 range (difference between minimum and maximum F0, shorter duration of sentences, and higher intensity of the first syllable of sentences. The findings were not influenced by the nature of the sentences (i.e. , declarative or interrogative, but for all variables they were significantly more severe in males than females. In conclusion, we have demonstrated that patients with acute SC have an impairment of modulation of F0 and longer duration of emission of sentences, resulting in a monotone and slow speech. This pattern is similar to what has been described in other basal ganglia illnesses, such as Parkinson's disease, Huntington's disease and Wilson's disease.Há poucos estudos sobre linguagem e fala em pacientes com coréia de Sydenham (CS. Fizemos uma análise acústica da freqüência fundamental (F0, duração e intensidade de sentenças declarativas e interrogativas feitas por 20 pacientes com CS, 20 pacientes com febre reumática (FR sem coréia, comparando-os com 20 controles saudáveis e pareados por idade (CO. Cada grupo incluiu 12 mulheres. Foi encontrado que não há diferença entre os grupos FR e CO quanto a todos parâmetros estudados. Pacientes com CS, contudo, apresentaram-se com fala caracterizada pela redução da variação de F0 (diferença entre F0 mínima e máxima, duração mais curta das sentenças e maior intensidade da primeira sílaba das sentenças. Os achados não foram

  14. Justicia, misericordia y cristianismo: una relectura de las inscripciones coránicas de la Mezquita de Córdoba en el siglo X

    Directory of Open Access Journals (Sweden)

    Calvo Capilla, Susana

    2010-06-01

    Full Text Available This article is a new analysis of the Koranic inscriptions that were made on the doors of the Great Mosque at Cordova during the time of the Caliphate (10th century. Although not all these inscriptions are well-preserved, a new approach to the Koranic verses has revealed enough unique aspects to suggest a fresh interpretation of their meaning and intention. These inscriptions are part of a well-defined epigraphic program with a complex meaning related to the political, social and religious context of the time. This program also accounts for allusions to the anti-Christian polemic of the era. In this sense, the religious epigraphy of this mosque constitutes a valuable historical record of the Umayyad caliphate of al-Andalus.

    En este artículo se realiza una relectura de las inscripciones de carácter religioso de las puertas de la Mezquita de Córdoba en época califal. A pesar de que no todas se han conservado, el estudio de conjunto reveló suficientes elementos singulares como para sugerir nuevas hipótesis en torno al sentido y la intencionalidad de los textos coránicos escogidos. Las inscripciones, tanto interiores como exteriores, conforman un programa epigráfico perfectamente coherente y dotado de un complejo significado ligado al contexto político, social y religioso de la época. El programa incluye asimismo alusiones a la polémica anti-cristiana en el siglo x. En ese sentido, la mezquita cordobesa constituye un valioso documento histórico del Califato omeya de al-Andalus.

  15. Efeito do armazenamento à baixa temperatura (-4 ºC na cor e no teor de acidez da farinha de trigo Effect of storage at low temperature (-4 ºC in the color and acidity content of wheat flour

    Directory of Open Access Journals (Sweden)

    Fernanda Ortolan

    2010-03-01

    Full Text Available Durante o armazenamento de farinha de trigo, podem ocorrer mudanças bioquímicas que resultam em alterações nutricionais e tecnológicas, sendo que em baixa temperatura estas mudanças ocorrem mais lentamente. Entre as alterações, pode-se citar o aumento da acidez, a redução do pH e as modificações na sua cor. O presente trabalho teve por objetivo avaliar os efeitos do armazenamento à baixa temperatura (-4 ºC na cor e na acidez da farinha de trigo durante seis meses e correlacionar os resultados obtidos para investigar se a acidez tem relação com a cor da farinha. Foram utilizadas farinhas provenientes de dez genótipos de trigo cultivados em Cascavel, no Estado do Paraná. A cor foi determinada no sistema CIEL*a*b* através dos parâmetros de cor: L* (luminosidade, a* e b* (coordenadas de cromaticidade. Usou-se procedimento da AOAC para determinação da acidez de lipídios. As farinhas apresentaram tendência ao branqueamento durante o período de seis meses de armazenamento, com ocorrência de leve aumento da acidez, mas dentro dos teores aceitáveis. A acidez não foi considerada um fator envolvido na alteração da cor das farinhas no armazenamento à baixa temperatura, pois não houve correlação entre estes dois parâmetros.During wheat flour storage, biochemical changes can occur which lead to nutritional and technological alterations, but in low temperature these changes can occur more slowly. Among the reactions, we may note are an increase in acidity, reduction of pH and modifications to its color. The present work aimed to evaluate the effects of storage at low temperature (-4 ºC on the color and acidity of wheat flour over six months and to correlate the results obtained to discover whether the acidity has any relationship with the color of the flour. Flours of ten wheat genotypes, cultivated in Cascavel, in Paraná State were used. The color was determined via the CIEL*a*b* system using the color parameters: L

  16. Influence of color on acceptance and identification of flavor of foods by adults Influência da cor na aceitação e identificação do sabor dos alimentos por adultos

    Directory of Open Access Journals (Sweden)

    Nayane Aparecida Araújo Dias

    2012-06-01

    Full Text Available The sensory characteristics color and flavor of food play an important role not only in the selection, but also in the determination of consumption, satiation, and ingestion. With the objective to determine and evaluate the influence of color on the acceptance and identification of flavor of foods for adults, sensory analysis was performed on jellies by non-trained tasters of both sexes aged between 18 and 60 years (1750 tests. A hedonic scale and combinations of five colors (red, yellow, green, blue and purple and three flavors (strawberry, pineapple, and limes were used in the acceptance test totaling 15 samples. In the duo-trio discrimination test, together with the reference sample (R, one sample identical to the reference and another of identical color and different flavor were offered, and the judges were requested to identify the sample that was different from the reference sample. The colors used did not influence the acceptance of the samples (P > 0.05, and as there was not significant interaction between color and flavor. However, the limes flavor negatively influenced acceptance when compared to the other flavors. With regard to flavor differentiation, the colors used did not influence flavor identification (P > 0.05; However, differentiated behavior was identified between females and males, and the latter were more error-prone. Therefore, under the experimental conditions tested, color did not influence the acceptance and identification of the flavor of the samples by adults.As características sensoriais cor e sabor dos alimentos desempenham papel importante não somente na seleção, como também na determinação do consumo, ingestão e saciedade. Objetivando determinar e avaliar a influência da cor na aceitação e identificação do sabor dos alimentos por adultos, foram realizados testes de análise sensorial com gelatinas por provadores não treinados, de ambos os gêneros, com idade entre 18 e 60 anos (1750 provas. No teste

  17. Mortalidade infantil segundo cor ou raça com base no Censo Demográfico de 2010 e nos sistemas nacionais de informação em saúde no Brasil

    Directory of Open Access Journals (Sweden)

    Aline Diniz Rodrigues Caldas

    Full Text Available O objetivo deste estudo é investigar as informações sobre mortalidade infantil no Brasil, de acordo com a cor ou raça com foco nos indígenas, baseando-se nos dados do Censo Demográfico de 2010 e daqueles oriundos do Sistema de Informação sobre Mortalidade (SIM e do Sistema de Informações sobre Nascidos Vivos (SINASC. Em ambas as fontes, as taxas de mortalidade infantil (TMI de indígenas foram as mais elevadas dentre os diversos segmentos populacionais. Apesar dos dados censitários indicarem desigualdades de cor ou raça, as TMI para indígenas e pretos foram inferiores às derivadas do SIM/SINASC. Particularidades metodológicas quanto à coleta dos dados em ambas as fontes devem ser consideradas. A redução da TMI no Brasil nas últimas décadas é em larga medida atribuída à prioridade da saúde infantil na agenda política. Os achados deste trabalho são indicativos de que o impacto das políticas públicas não alcançou os indígenas em mesma escala que o restante da população. Novas fontes de dados relativos à ocorrência de óbitos nos domicílios, de abrangência nacional, como é o caso do Censo de 2010, podem contribuir para uma melhor compreensão das desigualdades segundo cor ou raça no Brasil.

  18. Mortalidade por raça/cor: evidências de desigualdades sociais em Vitória (ES, Brasil Mortality by race/color: evidence of social inequalities in Vitória (ES, Brazil

    Directory of Open Access Journals (Sweden)

    Nathalia Modenesi Fiorio

    2011-09-01

    Full Text Available OBJETIVO: Analisar a mortalidade por causa básica, sexo e raça/cor a partir do sistema de informações sobre mortalidade (SIM, em Vitória (ES, no período de 2003 a 2006. MÉTODOS: Foram calculados e analisados os coeficientes de mortalidade, segundo causa básica e sexo por raça/cor, bem como a idade média e mediana de óbito por causa básica, sexo e raça/cor. Foi calculado o risco relativo (RR por sexo, idade e causa básica (pOBJECTIVE: To analyze mortality by cause and sex among groups of race or color from the mortality information system (MIS in Vitória (Brazil, in the period from 2003 to 2006. METHODS: We calculated and analyzed the mortality rates according to underlying cause, sex and race/color, and the mean and median age of death by underlying cause, sex and race. We calculated the relative risk (RR for age, sex and underlying cause (p<0.05 and CI 95%. RESULTS: The completeness of race/color in SIM ranged from 1% in 1996 to 81% in 2006. There was a greater RR of death among blacks for mental and behavioral disorders (RR=9.29, Ill-defined causes (RR=8.71, and external causes (RR=5.71. For black women, we highlight the external causes (RR=2.38. We found a variation of up to 33 years (nervous system between whites and blacks. CONCLUSION: This study confirms the existence of unequal racial/ethnic mortality, highlighting the mortality from mental disorders and external causes, in addition to early mortality that occurs in the black population.

  19. Síndrome de Aicardi e papiloma do plexo coróide: uma associação rara. Relato de caso Aicardi syndrome and choroid plexus papilloma: a rare association. Case report

    Directory of Open Access Journals (Sweden)

    Maria de Fátima M. Aguiar

    1996-06-01

    Full Text Available Relata-se o caso clínico de uma criança de 5 meses de idade, do sexo feminino, com achados característicos da síndrome de Aicardi: agenesia do corpo caloso, espasmos infantis, anormalidades oculares ("chorioretinal lacunae" e microftalmia, atraso do desenvolvimento neuropsicomotor e malformações vertebrais com cifoescoliose. Os exames complementares confirmaram o diagnóstico e as imagens neurorradiológicas evidenciaram, além da agenesia do corpo caloso, massa localizada em região atrioventricular esquerda (papiloma do plexo coróide. A síndrome de Aicardi associada a papiloma do plexo coróide é rara, sendo este o sétimo caso relatado na literatura. Os autores sugerem que o papiloma do plexo coróide seja considerado tumor característico da síndrome de Aicardi, pois a sua freqüência é mais do que coincidental.The authors report a case of a 5 months old female child with clinical features of Aicardi syndrome: agenesis of the corpus callosum, occular abnormalities ("chorioretinal lacunae" and microphthalmus, infantile spasms, mental retardation, vertebral malformations and thoracic deformity. The pacient was submitted to complementary examinations that confirmed the diagnosis. The neuroradiologic images (MRI showed besides corpus callosum agenesis a tumor located at the left ventricular atrium (choroid plexus papilloma. This association is a rare occurrence and the present case is the seventh described in literature. Furthermore, we suggest that the choroid plexus pappilloma could be a characteristic tumor of the Aicardi syndrome.

  20. Efeitos do exercício físico aeróbico sobre o remodelamento pulmonar e cardíaco no modelo experimental de cor pulmonale induzido por monocrotalina

    OpenAIRE

    Rafael Colombo

    2015-01-01

    O modelo experimental de Cor pulmonale é caracterizado por um processo de remodelamento vascular pulmonar devido a um insulto inflamatório inicial. O remodelamento vascular é influenciado por apoptose de células endoteliais, hipertrofia da túnica média de arteríolas e pequenas artérias, rarefação vascular e estresse oxidativo. Ao mesmo tempo em que nota-se um remodelamento vascular adverso é importante salientar que o ventrículo direito desempenha um trabalho contra a vasculatura pulmonar, co...

  1. Redução de cor ICUMSA em soluções concentradas de açúcar bruto por processo oxidativo com peróxido de hidrogênio

    Directory of Open Access Journals (Sweden)

    Juliana Lorenz Mandro

    2017-05-01

    Full Text Available Resumo A clarificação/purificação do açúcar refinado a partir de açúcares brutos, como Very High Polarization (VHP, é realizada atualmente pelo uso de resinas de troca-iônica ou carvão ativado. No entanto, são metodologias de alto custo, que necessitam de constante regeneração/recuperação e apresentam perda de capacidade em função do tempo de processamento. Neste sentido, estudos sobre tecnologias alternativas ao uso de resinas de troca-iônica e carvão ativado vêm sendo cada vez mais relacionados, para aumentar a economia do setor. O peróxido de hidrogênio em solução comercial (35%, v/v pode também ser entendido como agente promotor de redução de cor ICUMSA, na cadeia produtiva do açúcar refinado. Com isso, foram realizados tratamentos a fim de testar a eficiência do agente oxidante na clarificação de açúcar bruto do tipo VHP. Os tratamentos foram avaliados frente a diferentes doses de peróxido de hidrogênio, pH e temperaturas, durante um tempo reacional de uma hora. Todas as amostras tratadas apresentaram redução de cor ICUMSA, sendo que o maior decréscimo esteve na faixa de 67 a 70%. O aumento da dose de agente oxidante foi proporcional ao aumento de precipitados no meio, em que o tratamento com maior concentração de peróxido de hidrogênio apresentou índice de turbidez de 142 NTU em relação ao valor da amostra bruta (17 NTU, sendo o ensaio com maior turbidez. A degradação de sacarose ocorreu de forma mais pronunciada nos tratamentos com valores de pH abaixo de 5,0. Com isso, o peróxido de hidrogênio se mostrou uma alternativa viável para redução de cor ICUMSA e precipitação de não-açúcares e os tratamentos com melhor redução de cor também não foram críticos na degradação de sacarose.

  2. Metástase de coróide simulando síndrome de efusão uveal: relato de caso Choroidal metastasis simulating uveal effusion syndrome: case report

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Cury Júnior

    2008-04-01

    Full Text Available Descrição de um caso de efusão uveal secundária a metástase de coróide e revisão dos principais diagnósticos diferenciais. Uma paciente com baixa da acuidade visual, no olho esquerdo, apresentou nódulos ao nível da coróide, dispersão pigmentar retiniana e descolamento seroso da retina. O exame angiofluoresceinográfico demonstrou padrão "leopard spots", semelhante ao encontrado nos casos de efusão uveal. A ecografia ocular demonstrou a presença do descolamento seroso da retina, presença de espessamento e nódulos na coróide e a tomografia de coerência óptica evidenciou ruptura do epitélio pigmentado da retina, presença de nodulações coroidianas hiperrefletivas e áreas de descolamento de retina seroso. Após ser submetido a exames diagnósticos de imagem, constatou-se a presença de nódulo único no ápice pulmonar esquerdo. As metástases de coróide podem levar a um quadro similar à síndrome de efusão uveal. Esta possibilidade deve sempre ser pensada diante de um quadro de efusão uveal atípica e avaliação sistêmica para pesquisa de carcinoma deverá ser solicitada.We report a case of choroidal metastasis simulating uveal effusion syndrome. This patient with uveal metastasis from lung carcinoma presented with decreased vision in the left eye. Fundoscopic examination revealed pigmentary clumping, multiple choroidal nodules and serous retinal detachment. Fluorescein angioraphy revealed a leopard spots pattern similar to uveal effusion syndrome. Ultrasound revealed the presence of choroidal nodules with moderate internal reflectivity, choroidal thickening and serous retinal detachment. Optical coherence tomography showed retinal pigment epithelium tear and hyper-reflective nodules within the choroid and areas of serous retinal detachment. Image investigation demonstrated the presence of a solitary pulmonary nodule at the left apical lung. Choroidal metastasis can lead to a scenario that simulates uveal effusion

  3. Eficiência de diferentes tipos de coagulantes na coagulação, floculação e sedimentação de água com cor ou turbidez elevada.

    OpenAIRE

    Gerson Pavanelli

    2001-01-01

    A proposta deste trabalho foi utilizar quatro diferentes coagulantes - sulfato de alumínio, cloreto férrico, hidroxicloreto de aluminio e sulfato ferrico; construir os diagramas de coagulação; e assimilar as regiões de maior ou menor eficiência da remoção de turbidez ou da cor. Para permitir uma avaliação de custos na utilização dos coagulantes, observo-se nos diagramas as regiões onde os valores de turbidez remanescente são aproximadamente iguais para diferentes coagulantes. Com essa conside...

  4. Influência da coloração do substrato, espessura e translucidez da cerâmica na cor de facetas laminadas produzidas com o sistema CEREC inLab

    OpenAIRE

    Hilgert, Leandro Augusto

    2009-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Odontologia. O objetivo deste estudo in vitro foi investigar, espectrofotométrica e visualmente, a cor de facetas produzidas com um sistema CAD/CAM, com diferentes níveis de descoloração de substrato, espessuras de material e graus de translucidez das cerâmicas. Para isso, incisivos centrais superiores esquerdos de um modelo dental acrílico foram preparados para facetas com...

  5. Cor de feijão vagem fresco e processado após aplicação de cálcio Color of fresh and processed snap bean pods after calcium application

    Directory of Open Access Journals (Sweden)

    Simone Palma Fávaro

    2000-09-01

    Full Text Available A cor em vegetais é um dos principais atributos de qualidade observado pelo consumidor e é influenciada por características intrínsecas e de processamento. O objetivo desta investigação foi avaliar as alterações de cor de feijão vagem fresco e processado após aplicação de concentrações crescentes de cálcio via absorção radicular. O feijão vagem cultivar UEL 1 foi cultivado com aplicação de concentrações crescentes de cálcio via solução nutritiva contendo 0, 75 , 150 e 300 mL L-1 de cálcio em substrato de areia grossa. A cor das vagens ao natural e enlatadas foram avaliadas por colorimetria de três estímulos, e os resultados foram expressos no sistema Hunter. As vagens ao natural apresentaram-se mais claras e amarelas quando foi adicionado cálcio à solução nutritiva. O calor empregado no processo de enlatamento teve efeito pronunciado na redução da luminosidade e na cor verde, mesmo com o aumento na quantidade de cálcio nas vagens.The color in vegetables is one of the main quality attributes observed by the consumer and it is influenced by intrinsic characteristics and canning process. This research meant to investigate the effect of increasing calcium concentrations applied to a nutrient solution on physical measurements of the color of snap bean pods.This experiment was carried out wtih the cultivar UEL 1 grown in coarse sand with nutrient solution supplied at the following levels of calcium: 0, 75, 150 and 300 mL L-1. Fresh pods were analysed for calcium content. The fresh and canned pods were evaluated for color with tristimulus colorimetry and data were expressed according to the Hunter system. The fresh pods were lighter and yellowisher when calcium was added to the nutrient solution. The heat used for the canning process had a significant effect on reducing lightness and greeness, even with the greater amounts of calcium in the pods.

  6. Influência da fonte de luz fotoativadora nas propriedades ópticas de resína composta, em função da cor, espessura e tempo de armazenamento

    OpenAIRE

    Queiroz, Renato Souza [UNESP

    2010-01-01

    Esse estudo se propõe a avaliar as propriedades ópticas (Fluorescência e Absorbância) da resina composta fotoativada (4 SEASONS®) utilizando aparelho fotopolimerizador convencional (luz Halógena Ulttralux - DabiAtlant), e aparelho emissor de Diodo (Radii – SDI e Ultralume Led 5- Ultradent), em função da fonte de luz foto-ativadora, cor, espessura e tempo de armazenamento em saliva artificial. Foram confeccionadas 5 amostras (10,0x1,0 mm) para cada grupo experimental. Para a realização do test...

  7. Effect of soil management on the white grub population and damage in soybean Efeito do manejo de solo na população e nos danos de corós em soja

    Directory of Open Access Journals (Sweden)

    LENITA JACOB OLIVEIRA

    2000-05-01

    Full Text Available To evaluate the effect of soil management systems on population of white grubs, (Phyllophaga cuyabana Moser, and on its damage in soybean, experiments were set up under no-tillage and conventional tillage (one disk plow, and a leveling disk harrow areas. Primary tillage equipment, used in other soil management systems, such as moldboard plow, disk plow, chisel plow and heavy duty disk harrow were also tested. Fluctuation of P. cuyabana population and the extent of its damage to soybean was similar under no-tillage and conventional tillage systems. Results comparing a range of primary tillage equipment showed that it affected soil insect populations differently, depending on the time during the season in which tillage was executed. Larval mortality could mostly be attributed to their exposure to adverse factors, soon after tillage, than to changes in soil conditions. Reduction of white grub population was more evident in plots managed by heavier equipment, such as the moldboard plow. Soil tillage could be one component within the soil pest management system in soybean, however, its use can not be generalized.Foram realizados vários experimentos para avaliar o efeito de diferentes sistemas de manejo de solo na população de corós (Phyllophaga cuyabana Moser, e seus danos em soja, em áreas de plantio direto e de preparo convencional do solo (preparo primário com arado de discos e uma gradagem niveladora. Vários implementos utilizados no preparo primário de solo, como arado de aivecas, arado de discos, escarificador e grade aradora também foram avaliados. A flutuação populacional de corós e a intensidade de dano causado por eles foram similares nas áreas de plantio direto e de preparo convencional. Os implementos de preparo primário do solo afetaram a população de corós diferentemente, dependendo da época em que o preparo de solo foi executado. A mortalidade larval pode ser atribuída mais à exposição a fatores adversos logo ap

  8. As redes de solidariedade da cor: o caso dos compadres Manoel e Lauriano The Colour Solidarity Networks: the case of the 'compadres' Manoel and Laurino

    Directory of Open Access Journals (Sweden)

    Ivan de Andrade Vellasco

    2006-01-01

    Full Text Available O artigo baseia-se na analise de um processo criminal de 1831, no qual os réus, pardos, são acusados de assassinar um homem branco. No teor dos depoimentos revela-se a formação de uma aliança solidária dos pardos, em função das categorias que definem as posições e juízos a respeito do crime. Testemunhas pardas e crioulas, livres e forras, produzem um consenso construindo uma versão contra a vítima, o homem branco. Uma visão sobre o certo e o errado solidariza a todos e, dentro dela, uma percepção específica da justiça une pardos, crioulos e cabras. Propõe-se que a solidariedade com base na identidade entre "pardos" possa ter tido uma intencionalidade e motivações associadas aos debates políticos da época, travados entre liberais moderados e conservadores, a respeito da conceituação e inclusão dos ‘pardos’ no projeto de nação. Representa uma tentativa de se captar, nos indícios disponíveis, a formação de processos identitários com base na cor e na condição, categorias ordenadoras fundamentais da sociedade escravista.This article is based on the analysis of a criminal lawsuit from 1831, in which the accused ones, who were "mulattos", were charged with a white man murder. In the testimonies of the lawsuit, it is possible to identify a supportive alliance among the "mulattos", in relation to the categories that define the positions and judgements concerning to the crime. Witnesses, both "mulattos" and "negros", free and manumitted slaves, have produced a consensus, hence building a version against the victim, the white man. A view on right and wrong promotes solidarity in everybody and, within this view, a specific perception about what unites "mulattos", "negros", manumitted slaves and "cabras". We propose that the solidarity based on the identity among the "mulattos" can be understood in relation to the motivations associated to their emersion in the political debates of the time, concerning to their

  9. Con la guía del Corán: crisis y evolución del discurso numismático almohade

    Directory of Open Access Journals (Sweden)

    Peña Martín, Salvador

    2006-12-01

    Full Text Available First, we examine some unregistered Almohad and Post-Almohad coins, and discuss the attribution or reading of some others. As a result a discussion of a hypothesis on Idrīs al-Ma’mūn’s silver coins is offered and some new items are added to the numismatic corpus of Western Islam. This work leads us to a general overview of the Islamic discourse prevailing in Islamic Spain and North Africa after the so-called Almohad revolution. Considering this discourse as a dynamic work in progress, we focus on a number of issues: (1 the Qur’ānic aim of eternal life as a touchstone in the Almohad system of ideas, (2 the issue whether salvation is possible without actual human guides, (3 the evolution from negative to affirmative theology, (4 the ties binding the numismatic discourse and the Almohad and Post-Almohad ruling classes.

    Partimos de un recorrido histórico por acuñaciones almohades o postalmohades que, o bien no han sido registradas, o bien necesitan nuevas lecturas o atribuciones. Ello nos permite ofrecer una hipótesis sobre las monedas de plata acuñadas por Idrīs al-Ma’mūn y añadir algunos registros al corpus numismático del Occidente islámico en la Baja Edad Media. Ese trabajo nos permite, por otro lado, afrontar el discurso islámico dominante que surgió a raíz de la llamada revolución almohade, lo que hacemos centrándonos en varias cuestiones, entre ellas: 1 la densidad del mensaje sobre la vida eterna en las inscripciones almohades, que derivan de la fuente absoluta del Corán; 2 el problema de si es necesaria, de cara a la salvación, la presencia de guías históricos; 3 la evolución de la teología negativa a la afirmativa, y 4 la estrecha relación entre el discurso numismático y las elites almohades y postalmohades.

  10. [Analysis of prognostic risk factors in the patients with acute exacerbation of chronic cor pulmonale and obstructive sleep apnea-hypopnea syndrome in high altitude area].

    Science.gov (United States)

    Yang, Sheng-yue; Luo, Xiao-hong; Feng, En-zhi; Qi, Yu-shu; Liu, Rui-nian; Yin, He; Zhang, Ai-jun; Zhao, Li-hong

    2010-05-01

    To assess the prognostic risk factors in the patients with acute exacerbation of chronic cor pulmonale (AEHACCP) and obstructive sleep apnea-hypopnea syndrome (OSAHS) in high altitude area. The relations between neck circumference (Nc), body mass index (BMI), arterial blood gases, polysomnography (PSG) parameters and prognosis from 66 patients with AEHACCP and OSAHS (31 survivors, 35 non-survivors) were studied by one variable analysis and multivariable Logistic regression analysis. The results of one variable analysis showed that in patients with AEHACCP and OSAHS, Nc> or =45 cm, BMI > or =28 kg/m(2) , arterial oxygen partial pressure (PaO(2)) or =45 mm Hg, apnea-hypopnea index (AHI)> or = 40 times/h, sleep mean arterial oxygen saturation (MSaO(2)) or =50% and difference between basic and minimum SaO(2) during sleep(Delta SaO(2))> or = 0.20 were closely correlated with prognosis. The Logistic regression models showed that Nc> or =45 cm [odds ratio (OR)=6.781, 95% confidence interval (95%CI)=1.153-17.502, P=0.007], BMI> or =28 kg/m(2) (OR=7.562, 95%CI=1.012-23.457, P=0.004), mPAP> or =45 mm Hg (OR=6.991, 95%CI=1.353-20.155, P=0.003), AHI> or =40 times/h (OR=7.258, 95%CI=1.526-18.022, P=0.006), MSaO(2) or =50% (OR=5.593, 95%CI=1.265-21.589, P=0.008) and Delta SaO(2)> or =0.20 (OR=6.551, 95%CI=1.495-18.920, P=0.007) were independent significant risk factors in prognosis of patients with AEHACCP and OSAHS. The patients with AEHACCP and OSAHS, Nc> or =45 cm, BMI> or =28 kg/m(2), mPAP> or =45 mm Hg, AHI> or = 40 times/h, MSaO(2) or =50% and Delta SaO(2)> or =0.20 are risk factors leading to a rise in mortality. It is important to use these parameters to guide clinical therapy, and to judge the prognosis so as to reduce the mortality of patients with AEHACCP and OSAHS by monitoring the above risk factors in clinical practice.

  11. Expression levels of induced sputum IL-8 and IL-10 and drug intervention effects in patients with acute exacerbated COPD complicated with chronic cor pulmonale at high altitude.

    Science.gov (United States)

    Feng, Enzhi; Wan, Ronghua; Yang, Shengyue; Yan, Ziqiang; Wang, Shaolin; He, Wei; Zhang, Ying; Yin, He; Chen, Zongru; Liu, Ruinian

    2013-09-01

    The aim of this study was to assess the expression levels of induced sputum interleukin (IL)-8 and IL-10 levels in patients with acute exacerbated chronic obstructive pulmonary disease (AECOPD) complicated with chronic cor pulmonale (CCP) at high altitude, and to evaluate the intervention effects of an inhaled corticosteroid (ICS) and a β 2 -adrenoceptor agonist in this disease. A total of 186 patients with AECOPD complicated with CCP were randomly divided into three groups, with 62 cases in each. With regard to the two treatment groups, group A was treated with salmeterol/fluticasone (50 μg/250 μg, respectively) by airway inhalation twice daily, while group B received budesonide (1 mg) as a spray inhalation, twice daily. The routine treatment group (group C) received only routine treatment. The levels of IL-8 and IL-10 in the induced sputum and the predicted percentage of forced expiratory volume in one second (FEV 1%pred ), partial pressure of oxygen in arterial blood (PaO 2 ) and partial pressure of carbon dioxide in arterial blood (PaCO 2 ) were examined on admission and at a stable stage two weeks following treatment. Forty healthy volunteers served as a control group (group D). Compared with group D values, the IL-8 induced sputum level and the PaCO 2 were significantly increased, while the level of IL-10, FEV 1%pred and the PaO 2 were markedly decreased in the three COPD groups prior to treatment. Following treatment, the induced sputum IL-8 level and the PaCO 2 were significantly decreased, while the induced sputum IL-10 level, FEV 1%pred and the PaO 2 were markedly increased in the three treatment groups compared with the values pre-therapy (all P<0.01). The post-treatment parameters were significantly different among the three groups (P<0.01). The results indicate that IL-8 and IL-10 are involved in the airway inflammation of AECOPD complicated by CCP. Treatment with an ICS was demonstrated to be a successful method of reducing the local expression of

  12. Plasma endothelin-1 and nitric oxide correlate with ligustrazine alleviation of pulmonary artery hypertension in patients of chronic cor pulmonale from high altitude plateau during acute exacerbation.

    Science.gov (United States)

    Feng, En-Zhi; Yang, Sheng-Yue; Huang, Ning-Xia; Yin, He; Zhang, Ying; Tian, Zhong-Xin

    2014-11-01

    To explore the mechanisms involved in the ligustrazine alleviation of the pulmonary artery hypertension (PAH) in patients of chronic obstructive pulmonary disease (COPD) associated with chronic cor pulmonale (CCP) during exacerbation. Seventy patients of COPD and CCP with acute exacerbation were randomly and equally divided into control group and treatment group. The control group received standard treatment with antibiotics, antiasthmatic and expectorant medications, and oxygenation; and the ligustrazine treatment group received ligustrazine treatment (80 mg/d; i.v.; for 2 weeks) in addition to the standard treatment. Before and at the end of 2 week treatment, the clinic responses of the two regimens were evaluated, plasma levels of endothelin-1 (ET-1) and nitric oxide (NO) were determined; arterial oxygen partial pressure (PaO2, mean pulmonary arterial pressure (mPAP), outflow tract of right ventricle (RVOT), and internal diameter of right ventricle (RV) were measured. Good clinic benefits were achieved in both the standard and ligustrazine regimens, plasma level of ET-1, values of mPAP, RV and RVOT decreased significantly, plasma level of NO and PaO2 values decreased (all P < 0.01 vs pre-treatment to all parameters). Compared with the control group, ligustrazine greatly enhanced the clinic efficacy from 77.1% to 97.1% (P < 0.05), and also resulted in more significant changes of all these parameters (P < 0.01 vs control group for all parameters). For both groups, the levels of plasma ET-1 were positively correlated with values of mPAP, RVOT, and RV (r = 0.710, 0.853, and 0.766, respectively, all P = 0.000), and negatively correlated with plasma NO and PaO2 (r = - 0.823, and - 0.752, respectively, all P = 0.000). Ligustrazine is effective in treating pulmonary artery hypertension during acute exacerbation of COPD and CCP in patients from the plateau area. The observed changes in the plasma levels of NO and ET-1 in response to ligustrazine treatment suggest that

  13. Cenas da circulação: fragmentos de uma etnografia sobre homossexualidade, gênero, cor e mestiçagem em uma favela do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Silvia Aguião

    Full Text Available Este artigo expõe parte de uma etnografia desenvolvida na favela de Rio das Pedras com enfoque orientado para questões relacionadas à sexualidade, gênero, cor/raça e mestiçagem. Localizada na cidade do Rio de Janeiro, a favela é reconhecida por duas características particulares: a ausência do tráfico armado de drogas e a intensa imigração nordestina. A partir de algumas cenas recortadas do trabalho de campo, busca-se explorar como estes aspectos imprimem conformações específicas às experiências e às representações sobre homossexualidade, gênero e cor/raça, procurando observar como a interseção destes aspectos relaciona-se a processos de diferenciação social e perpassa estruturas e hierarquias sociais nesse espaço.

  14. PARÂMETROS DE COR E TURBIDEZ RELACIONADOS AOS USOS DO SOLO E À MORFOMETRIA DA BACIA HIDROGRÁFICA DO RIO TAQUARAL, SÃO MATEUS DO SUL-PR

    Directory of Open Access Journals (Sweden)

    Ângela Marli Ewerling Luíz

    2012-04-01

    Full Text Available O presente artigo teve por objetivo relacionar aspectos morfométricos e de usos do solos com os parâmetros aquáticos de cor e turbidez do Rio Taquaral, São Mateus do Sul. Após a caracterização da área, foram implantados ao longo do rio, dois pontos de observação de dados pluviométricos e de coleta de água. As coletas foram submetidas à análise no laboratório da SANEPAR. Os resultados indicaram que na média, os índices de cor da água se apresentaram acima dos padrões da Resolução CONAMA 357/05. Já os de turbidez estavam dentro dos padrões dessa resolução. Estes se apresentaram mais elevados no alto curso, onde se pratica agricultura temporária e mecanizada.

  15. Comprovação anatomopatológica da presença de tecido vascular e nervoso evidenciado à ecografia como eco tangencial ao descolamento de coróide: relato de dois casos Histopathologic confirmation of vascular and nervous tissue identified on ultrasound as an tangential image to choroidal detachment: report of two cases

    Directory of Open Access Journals (Sweden)

    Eduardo F. Marback

    2009-12-01

    Full Text Available São apresentados dois casos de descolamento de coróide em olhos com endoftalmite submetidos a enucleação. O estudo anatomopatológico permitiu identificar a presença de tecido vascular e nervoso interpondo-se entre a esclera e coróide deslocada, como havia sido evidenciado pela ecografia.Two cases of endophthalmitis with choroidal detachment submitted to enucleation are presented. The histopathologic study allowed the identification of vascular and nervous tissue between the choroid and sclera, as it was seen on ultrasound examination.

  16. Proteinas do liquido cefalorraqueano: III. Valores normais das imuneglobulinas G, A e M (variações ligadas a cor, sexo e idade

    Directory of Open Access Journals (Sweden)

    Lucia M. Singer Vermes

    1983-03-01

    Full Text Available É apresentada inicialmente revisão de literatura a respeito dos resultados obtidos na determinação das taxas de imuneglobulinas do LCR normal, mediante diferentes métodos, assim como da influência dos fatores cor, sexo e idade, nestes valores. Mediante imunodifusão radial foram determinados os níveis de IgG, IgA e IgM do LCR normal de 115, 78 e 45 pessoas, respectivamente. Todas as amostras de LCR foram obtidas por punção sub-occipital (LCR-SO. Os resultados destas determinações permitiram concluir que: a as taxas médias de IgG, IgA e IgM do LCR de pretos ou pardos não diferem daquelas de brancos; b não existem variações ligadas ao sexo, nem à idade, em crianças com 1 a 11 anos, nas taxas das imuneglobulinas estudadas, no LCR; c os níveis fisiológicos em crianças com 1 a 11 anos, para IgG variam entre 0,21 e 2,93 mg/100 ml; os teores absolutos médios de IgG de crianças são inferiores àqueles encontrados em adultos; os níveis percentuais médios de IgG de crianças não diferem daqueles de adultos; d as taxas de IgA do LCR de crianças, tanto em valores absolutos como relativos, são, em média, inferiores àquelas encontradas em adultos, não ultrapassando, em condições normais, 0,15 mg/100 ml (0,7% do total protéico; e em adultos, não se observam variações ligadas ao sexo, nem à idade, nos níveis das imuneglobulinas estudadas, no LCR-SO; as taxas normais de IgG encontradas no LCR-SO de adultos são de 0,51 a 4,00 mg/100 ml; em crianças e adultos, as taxas fisiológicas desta imuneglobulina, em termos percentuais, são de 3 a 12%; o LCR-SO normal de adultos contém IgA em concentrações de até 0,32 mg/100 ml (0,9% do total protéico; f a IgM encontra-se no LCR-SO normal, tanto de crianças como de adultos, em níveis muito baixos, não ultrapassando 0,2 mg/100 ml (0,25% do total protéico.

  17. Leer a Maquiavelo, traducir el Corán: Muḥammad, príncipe y legislador en el Alcorano di Macometto (Venecia, 1547

    Directory of Open Access Journals (Sweden)

    Mattia Tommasino, Pier

    2013-02-01

    Full Text Available This article focuses on L’Alcorano di Macometto, written by Giovanni Battista Castrodardo from Belluno (1588 ca.-1517 ca., and published by Andrea Arrivabene at Venice in 1547. Although this text is considered to be a paraphrase of the Latin translation of the Qur’ān made by Robert of Ketton (1143 AD, a closer look shows that it was a handy pocket encyclopedia of the history of Islam and the Ottoman empire. Following a suggestion of Alessandro D’Ancona (1889, I analyze the historical texts published in the introduction to the Alcorano and especially Castrodardo’s biography of the prophet Muḥammad. This biography includes a prayer addressed to Muḥammad through the character of the monk Sergio-Bahīrā in order to persuade him to dethrone Emperor Heraclius. A deep linguistic analysis of this speech sheds light on Castrodardo’s reading of Machiavelli. While this new portrayal of Muhammad is based on medieval sources, it presents the Prophet of Islam as a distinctly Renaissance Prince, a lawgiver and a “Prophet Armed”. It also reflects the pro-Ottoman and anti-Imperial hopes of Italian circles linked to the French embassy in Venice.Este artículo se centra en L’Alcorano di Macometto, escrito por Giovanni Battista Castrodardo de Belluno (1517 ca.-1588 ca. e impreso por Andrea Arrivabene en Venecia en 1547. Aunque hoy sea considerado como una torpe paráfrasis de la traducción latina del Corán de Roberto de Ketton (1143 AD, un examen atento demuestra que L’Alcorano costituyó una práctica y exitosa enciclopedia de bolsillo sobre la historia del islam y del Imperio otomano. Siguiendo una intuición de Alessandro D’Ancona (1889, analizo los textos históricos publicados en la introducción del texto, centrándome especialmente en la biografía del profeta Muḥammad escrita por Castrodardo. Dicha biografía presenta una larga oración renacentista pronunciada por el monje Sergio-Bahīrā para convencer a Muḥammad a derrocar

  18. Avaliação do desempenho hemodinâmico do dispositivo de assistência ventricular InCor como substituto do coração esquerdo Analysis of the hemodynamic performance of the InCor ventricular assist device as a substitute for the left heart

    Directory of Open Access Journals (Sweden)

    Anderson BENÍCIO

    1999-07-01

    Full Text Available FUNDAMENTO: A assistência circulatória mecânica é uma opção terapêutica em casos de choque cardiogênio refratário ao tratamento farmacológico, sendo freqüentemente utilizada como ponte para o transplante cardíaco. OBJETIVO: Avaliar o desempenho do Dispositivo de Assistência Ventricular (DAV desenvolvido pela Bioengenharia do Instituto do Coração, quando implantado com substituto do coração esquerdo. CASUÍSTICA E MÉTODOS: Foram estudados 10 bezerros da raça Girolando com peso médio de 73 kg. O implante DAV-InCor foi realizado com a cânula de drenagem posicionada no átrio esquerdo (AE ou na ponta do ventrículo esquerdo (VE e a cânula de reposição implantada na aorta torácica descendente. As pressões do coração direito e esquerdo, débito cardíaco e o fluxo do DAV foram determinados antes e após a indução farmacológica de insuficiência miocárdica, na vigência de diferentes níveis de vácuo do sistema de drenagem. RESULTADOS: Com a drenagem no AE, os valores do fluxo do DAV foram de 2,2 ± 0,5 l/min na condição sem vácuo, 3,7 ± 0,4 l/min com vácuo de 10 mmHg, de 4,3 ± 0,4 com vácuo de 20 mmHg e de 4,8 ± 0,6 com vácuo de 30 mmHg. Os valores da pressão de AE foram de 11,7 ± 6; 9,8 ± 5,3, 8,5 ± 4,4 e 5,6 ± 3,3 mmHg nas mesmas condições, respectivamente. Com a cânula ventricular, o fluxo DAV foi de 4,2 ± 0,6 na condição sem vácuo e de 4,4 ± 0,7 com vácuo de 10 mmHg, sendo observados valores de pressão de AE de 11,1 ± 2 e 10,3 ± 3,5 mmHg nas duas condições. Esses resultados foram observados em condições hemodinâmicas semelhantes, sendo o fluxo do DAV responsável por um porcentual maior do débito cardíaco total conforme o nível de vácuo. Esse porcentual foi de 86 ± 13% com a cânula atrial e vácuo de 30 mmHg e de 97 ± 3% com a drenagem ventricular e vácuo de 10 mmHg. CONCLUSÕES: O DAV-InCor mostrou-se eficiente como substituto do ventrículo esquerdo. O desempenho deste

  19. El gesto coréutico en la música hispánica de la segunda mitad del siglo XVIII: una propuesta de interpretación históricamente informada del fandango

    Directory of Open Access Journals (Sweden)

    María José Ruiz Mayordomo

    2015-01-01

    Full Text Available Dentro del marco que ofrece este congreso dedicado al fandango, el equipo formado por la coreóloga María José Ruiz Mayordomo y la musicóloga Aurèlia Pessarrodona quiere presentar un estudio de este género desde su gesto, un aspecto prácticamente ausente dentro de los múltiples enfoques de los que ha sido objeto. Nuestra propuesta parte de una metodología transdisciplinar (músicocoréutica y teóricopráctica que analiza la gestualidad de la obra musical misma captada a través del cuerpo danzante ideal de la segunda mitad del siglo XVIII, estableciendo a su vez un diálogo con el entorno coréutico de la época. Nuestro objetivo en este trabajo es restaurar un fandango de teatro del siglo XVIII. Ante la escasez de testimonios escritos, tomamos como fuentes principales fandangos coréuticos antiguos conservados en la tradición bolera, transmitida de manera ágrafa, oral, visual, corporal y artística, es decir, por aprendizaje directo entre transmisor repetidor y maestro e intérprete. En este caso partimos del baile conocido como Fandango del Siglo XVIII, cuya coreografía encaja perfectamente con la música de un fandango de teatro de finales de siglo XVIII compuesto por Bernardo Álvarez Acero. El análisis de la relación entre gestos musicales y coréuticos de ambas obras proporciona claves para entender estos y otros fandangos musicales de la época. Así pues, esta propuesta pretende acercar a teóricos e intérpretes al fenómeno del fandango de un modo más integral, de cara a restaurar e interpretar estas obras desde un punto de vista coreográfica y coreológicamente informado.

  20. AIDS mortality, "race or color", and social inequality in a context of universal access to highly active antiretroviral therapy (HAART in Brazil, 1999-2004 Mortalidade por AIDS, "raça/cor" e desigualdade social, em um contexto de acesso universal à terapia anti-retroviral de alta potência (HAART no Brasil, 1999-2004

    Directory of Open Access Journals (Sweden)

    Maria Goretti P. Fonseca

    2007-01-01

    Full Text Available Highly active antiretroviral therapy (HAART has led to a substantial increase in the survival of people living with AIDS, despite heterogeneities among individuals from different socioeconomic strata. The present paper analyzes AIDS deaths in Brazil during a period in which HAART became a key treatment regimen, exploring the hypothesis that "race or color" defines one dimension of socioeconomic inequality in Brazil. AIDS mortality, stratified by gender and "race or color", was calculated using data from the National Mortality System. The rates were highest among individuals classified as "black" and lower among those classified as "mixed-race", with a continuous increase among the later from 1999 to 2004 for men and women. Among individuals classified as "white", mortality rates remained stable among men, but not women. Median age at death among "mixed-race" individuals was lower for both men and women. Differential trends according to gender and "race or color" were highlighted by the present study, indicating the pressing need to further explore the underlying factors that might explain different mortality rates in a context of universal access.A terapia anti-retroviral de alta potência (HAART tem determinando substancial aumento da sobrevida de pessoas vivendo com AIDS, ainda que de forma heterogênea entre populações de diferentes condições sociais e econômicas. Este estudo analisa a mortalidade por AIDS no Brasil, num período em que a HAART se consolida como estratégia terapêutica, explorando a hipótese da variável "raça/cor" constituir uma das vertentes das desigualdades sociais e econômicas no Brasil. Foram calculadas taxas de mortalidade por AIDS, por sexo e "raça/cor", utilizando-se dados do Sistema de Informações sobre Mortalidade. As maiores taxas de mortalidade foram observadas nos indivíduos de "raça/cor" preta e as menores naqueles de "raça/cor" parda, ainda que com crescimento persistente no período observado

  1. Estudo comparativo da flarefotometria em pacientes com melanoma maligno e nevo de coróide Comparative study of flare photometry in patients with choroidal malignant melanoma and choroidal nevus

    Directory of Open Access Journals (Sweden)

    Priscilla Luppi Ballalai

    2002-01-01

    Full Text Available Introdução: Os tumores malignos intra-oculares estão associados com um aumento do "flare" na câmara anterior, causado por uma quebra na barreira hemato-aquosa, que pode ocorrer por vários mecanismos. Estudos utilizando a flarefotometria confirmam o aumento do "flare" em olhos com tumores intra-oculares malignos e benignos. Objetivo: Avaliar a flarefotometria como auxiliar no diagnóstico diferencial de melanoma maligno e nevo de coróide, comparando-se com olhos contralaterais normais. Métodos: Foram avaliados olhos com melanoma maligno e olhos com nevo de coróide diagnosticados por meio de oftalmoscopia indireta e/ou ultra-sonografia. Os olhos normais contralaterais foram utilizados como controles. A flarefotometria foi realizada em todos os pacientes, sob midríase bilateral, utilizando equipamento Laser Flare Meter (FC 500, Kowa. Foram aplicados os testes de Wilcoxon, Mann-Whitney, e Spearman para análise estatística. Resultados: A média da flarefotometria nos olhos com melanoma maligno de coróide foi 17,1 ph/ms e nos olhos normais contralaterais foi 4,06 ph/ms. Nos olhos com nevo de coróide o valor da flarefotometria foi 6,12 ph/ms e nos olhos contralaterais normais foi 4,47 ph/ms. O valor da flarefotometria foi maior nos olhos com melanoma maligno e nevo quando comparado com os olhos contralaterais normais (pIntroduction: Malignant intraocular tumors are associated with an increase in the aqueous flare, caused by alterations of the blood-ocular barriers through various mechanisms. Several studies have demonstrated an ocular flare increase using flare photometry in eyes with benign and malignant tumors. Purpose: To evaluate flare photometry as an adjunct method in the differential diagnosis of choroidal malignant melanoma and choroidal nevus comparing to normal control eyes. Methods: Eyes with melanoma and nevus were diagnosed by indirect binocular ophthalmoscopy and/or ultrasound were evaluated. The fellow normal eyes were used

  2. Chemical composition, color and sensory quality of tomato dried at different temperaturesComposição química, cor e qualidade sensorial do tomate seco a diferentes temperaturas

    Directory of Open Access Journals (Sweden)

    Gilberto Costa Braga

    2012-08-01

    Full Text Available This study evaluated the effect of drying temperature on the total phenolic compounds, lycopene and ascorbic acid contents, color and sensory quality of dried tomato. Tomatoes cv. Dominador were dried at 55, 65, 75 and 85 °C. The instrumental color of dried tomato was determined separately on the sides of pulp and peel. In affective sensory analysis appearance, color, aroma, flavor and texture attributes were considered. Acceptance index and purchase intent were also evaluated. According to the results, increasing concentrations of phenolic compounds and lycopene were observed with increased drying temperature to 75 °C. Significant decrease in ascorbic acid content was observed during drying, which ranged from 38.82 ± 2.47 mg 100 g-1 after drying at 55 °C, dropping to 21.68 ± 1.30 mg 100 g-1 at 85 °C. Significant decrease in values of a* and L* were observed on both sides of the dried tomato slices (pulp and peel, showing that the increase in temperature causes loss of red color and browning of dried tomato. According to sensory analysis, among the temperatures tested in drying tomatoes the one that showed best results was 75 °C. This study showed that drying-conventional tomato with air heated to 75 °C is the most recommended among the temperatures tested. Neste trabalho foi avaliado o efeito da temperatura de secagem nos conteúdos de compostos fenólicos totais, licopeno e ácido ascórbico, na cor e qualidade sensorial do tomate seco. Tomates cultivar Dominador foram secos a 55, 65, 75 e 85 ºC. A cor instrumental do tomate seco foi determinada separadamente nos lados da polpa e da casca. Na análise sensorial afetiva, foram analisados os atributos aparência, cor, aroma, sabor e textura. O índice de aceitabilidade e a intenção de compra também foram considerados. De acordo com os resultados, concentrações crescentes de compostos fenólicos totais e licopeno foram verificadas com o aumento da temperatura de secagem do tomate

  3. Saint-André-des-Eaux (Côtes-d’Armor : nouveaux éléments sur l’église et sur ses décors peints

    Directory of Open Access Journals (Sweden)

    Mathias Dupuis

    2009-09-01

    Full Text Available Nous avions déjà présenté dans le précédent numéro du Bulletin du Centre d'études médiévales d’Auxerre les premières recherches sur l’ancienne église paroissiale de Saint-André-des-Eaux . La réalisation de sondages en juin 2008 ainsi qu’une dernière série d’observations sur le bâti, préalables à la consolidation des murs de l’église et des vestiges de peintures murales, permettent désormais de mieux cerner l’histoire monumentale de cet édifice et de ses décors peints.Quatre sondages ont été o...

  4. Longevity of africanized worker honey bees (Apis mellifera carrying eye color mutant alleles Longevidade de operárias Apis mellifera africanizadas portadoras de mutações para a cor dos olhos

    Directory of Open Access Journals (Sweden)

    Rosana de Almeida

    2003-01-01

    Full Text Available The dark coloration of insects eyes is attributed to the accumulation of the brown pigment insectorubin, a mixture of ommochromes, xanthommatin and several ommins, biosynthesized from tryptophan. When any of the events in the synthesis chain is interrupted, formation and accumulation of pigments other than insectorubin occurs, and a new eye color will appear. The aim of the present work is to evaluate the longevity of worker honey bees Apis mellifera, homozygous and heterozygous for the mutant alleles cream (cr, snow-laranja (s la and brick (bk. Eye pigmentation and average longetivity of bees are very closely related. Mutant bees carrying lighter eye pigmentation are unable to return to the hive; there is, therefore, a close association between the eye pigmentation and honey bees lifespan. Experiments ran in confinement cages confirm the orientation problems of mutant honey bees, which kept in a limited space, were able to return to the hive and had an extended lifespan in comparison to that observed in the nature, and did not present statistical difference (P>0.05 relative to the control group. Confinement to restricted areas improves honey bees orientation abilities and facilitates return to the hive.Os olhos das abelhas selvagens adultas apresentam coloração marrom-escura, devido à presença de pigmentos denominados omocromos-xantominas e diferentes tipos de ominas. Os principais passos da cadeia metabólica que determinam a biossíntese desses pigmentos iniciam-se a partir do triptofano e qualquer interrupção em um dos seus passos fará com que a cor marrom-escura seja substituída por uma nova cor. Estudou-se a longevidade de operárias de Apis mellifera portadoras dos alelos mutantes para a cor dos olhos cream (cr, snow-laranja (s la e brick (bk. Existe nítida relação entre o grau de pigmentação dos olhos e a longevidade média das abelhas. As abelhas mutantes que apresentam a cor dos olhos mais clara perdem-se no campo, quando

  5. Raça, cor e etnia em estudos epidemiológicos sobre populações brasileiras: revisão sistemática na base PubMed

    OpenAIRE

    Kabad,Juliana Fernandes; Bastos,João Luiz; Santos,Ricardo Ventura

    2012-01-01

    O objetivo foi analisar o uso das variáveis raça, cor e etnia em estudos epidemiológicos sobre populações brasileiras. Trata-se de revisão sistemática, conduzida na base PubMed,entre janeiro de 2000 e julho de 2010. Para o conjunto dos trabalhos revisados, aplicou-se ficha com questões sobre seus objetivos e a relevância da classificação étnico-racial em suas análises, características sócio-demográficas e aspectos da identificação étnico-racial das populações investigadas, bem como o seguimen...

  6. Efeitos da cor, iluminação e rotação na ilusão estereoscópica da máscara côncava

    Directory of Open Access Journals (Sweden)

    Maria Amélia Cesari Quaglia

    2015-06-01

    Full Text Available Na ilusão da máscara côncava, o reverso côncavo da máscara é percebido como uma face convexa. Esta pesquisa objetivou investigar a robustez dessa ilusão em fotografias de estereogramas da máscara côncava sob variações de cor, iluminação e rotação. Quarenta observadores julgaram como côncava, plana ou convexa máscaras côncavas cinza e policromada, iluminadas por cima, baixo, direita, esquerda, e invertida iluminada por baixo, apresentadas num monitor. A maioria julgou a máscara côncava como convexa. Eles também reproduziram, em centímetros, a profundidade percebida entre a ponta do nariz da máscara e sua base. Não foi observado efeito para a cor, F(1,39=0,22; p>0,05, mas ocorreu um efeito principal para a direção da iluminação, F(4,156=11,35; p<0,05. Observou-se uma diferença significativa entre estimativas da posição da máscara côncava monocromada, t(39=2,12; p<0,05. Maiores estimativas foram designadas às máscaras côncavas posicionadas verticalmente iluminadas por baixo. Estes resultados indicaram a atuação dos processos top-down sobre os bottom-up.

  7. Efeito de parâmetros de extrusão na cor E propriedades de pasta da farinha de mandioquinha-salsa (Arracacia xanthorrhiza Effect of extrusion parameters on color and pasting properties of peruvian carrot flour (Arracacia xanthorrhiza

    Directory of Open Access Journals (Sweden)

    Bruna Menegassi

    2007-12-01

    Full Text Available Processou-se neste trabalho a farinha de mandioquinha-salsa (Arracacia xanthorrhiza Bancr. em uma linha de extrusão (mono rosca variando as condições operacionais: umidade da farinha (11-19%, temperatura de extrusão (86-154ºC e taxa de rotação da rosca (136-272rpm. Os parâmetros de cor analisados foram luminosidade (L* e os componentes de cromaticidade a* e b*. Os parâmetros de propriedade de pasta analisados foram viscosidade inicial, pico de viscosidade, quebra de viscosidade, tendência a retrogradação e viscosidade final. Os resultados obtidos mostraram que a umidade da matéria-prima interferiu nos componentes de cor das farinhas com efeito significativo sobre a luminosidade e croma a*, e a temperatura interferiu no croma b* . Quanto ao efeito dos parâmetros de processo sobre as propriedades de pasta, a umidade interferiu nas viscosidades inicial e final dos produtos, pico e quebra de viscosidade, enquanto a temperatura de extrusão e a rotação da rosca tiveram influência sobre a tendência a retrogradação e viscosidade final dos produtos.In this work peruvian carrot flour (Arracacia xanthorrhiza Bancr. was processed in a single screw extruder at different moisture contents (11-19%, extrusion temperature (86-154ºC and screw speed (136-272rpm. The parameters L*, a* and b* of color were analyzed in extruded flours. The viscosity related parameters determined include initial viscosity, viscosity peak, breakdown, setback and final viscosity. The results showed effect of feed moisture on flour color (L* and a* and the extrusion temperature influenced b*. Moisture content of the feed had effect on initial and final viscosity, viscosity peak and breakdown. Extrusion temperature and screw speed had effect on final viscosity and setback.

  8. Application of the LI-COR CO2 analyzer to volcanic plumes: a case study, volcán Popocatépetl, Mexico, June 7 and 10, 1995

    Science.gov (United States)

    Gerlach, T.M.; Delgado, H.; McGee, K.A.; Doukas, M.P.; Venegas, J.J.; Cardenas, L.

    1997-01-01

    Volcanic CO2 emission rate data are sparse despite their potential importance for constraining the role of magma degassing in the biogeochemical cycle of carbon and for assessing volcanic hazards. We used a LI-COR CO2 analyzer to determine volcanic CO2 emission rates by airborne measurements in volcanic plumes at Popocatépetl volcano on June 7 and 10, 1995. LI-COR sample paths of ∼72 m, compared with ∼1 km for the analyzer customarily used, together with fast Fourier transforms to remove instrument noise from raw data greatly improve resolution of volcanic CO2 anomalies. Parametric models fit to background CO2 provide a statistical tool for distinguishing volcanic from ambient CO2. Global Positioning System referenced flight traverses provide vastly improved data on the shape, coherence, and spatial distribution of volcanic CO2 in plume cross sections and contrast markedly with previous results based on traverse stacking. The continuous escape of CO2 and SO2 from Popocatépetl was fundamentally noneruptive and represented quiescent magma degassing from the top of a magma chamber ∼5 km deep. The average CO2 emission rate for January-June 1995 is estimated to be at least 6400 t d−1, one of the highest determined for a quiescently degassing volcano, although correction for downwind dispersion effects on volcanic CO2 indicates a higher rate of ∼9000 t d−1. Analysis of random errors indicates emission rates have 95% confidence intervals of ∼±20%, with uncertainty contributed mostly by wind speed variance, although the variance of plume cross-sectional areas during traversing is poorly constrained and possibly significant.

  9. Cor, gênero e classe: dinâmicas da discriminação entre jovens de grupos populares cariocas Color, gender and social class: dynamics of discrimination of lower income youth from Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Simone Monteiro

    2009-06-01

    Full Text Available Este trabalho discute as dinâmicas de discriminação entre moças e rapazes das camadas populares do Rio de Janeiro, considerando o papel que as hierarquias de cor/raça, gênero e classe social desempenham na configuração das práticas sociais. A análise tem por base entrevistas em profundidade com 42 jovens, de 18 a 24 anos. As situações de discriminação são referidas com maior frequência pelos rapazes. Entre os homens tais experiências estão associadas principalmente aos espaços públicos e ao mercado de trabalho, enquanto entre as mulheres a discriminação está mais vinculada aos espaços privados e ao local de moradia. Os dados estimulam uma discussão sobre a heterogeneidade das experiências de discriminação, na qual a cor/raça está associada às condições sociais e às relações de gênero.This work discuss the dynamics of discrimination of lower income male and female youths from Rio de Janeiro, considering the impact of the color/race, gender and social class hierarchies in the configurations of social practices. The analysis is based on in-depth interviews of 42 young people from 18 to 24 years of age. Situations of discrimination are much more referred to by men. The public spaces and the labor market are cited mainly by the boys. In the girls' view the discrimination is more associated to the place of residence and the private sphere. These data stimulate an analysis about the heterogeneity of the experiences of discrimination, where color/race is associated to social condition and gender relations.

  10. L'exemple d'un décor religieux dans le nord de la France : Bruno Chérier (1817-1880 et Notre-Dame-des-Anges de Tourcoing

    Directory of Open Access Journals (Sweden)

    Catherine Guillot

    2012-04-01

    Full Text Available Ami et modèle du sculpteur Jean-Baptiste Carpeaux, Bruno Chérier (1817 Valenciennes, 1880 Paris se consacre à partir de la fin des années 1850 jusqu'à sa mort au décor religieux dans le nord de la France. Devenu en 1852 professeur aux écoles académiques de Tourcoing, il répond aux commandes les plus variées dans le domaine de l'art religieux. Ainsi, sa participation au décor de l'église Notre-Dame-des-Anges de Tourcoing est exemplaire de la diversité de ses contributions : chemin de croix, cartons de vitraux, peintures ornementales illusionnistes. Cette église constitue en outre dans le Nord un des rares témoignages conservé presque intégralement de l'art religieux dans la seconde moitié du XIXe siècle. La collaboration de Chérier à ce chantier témoigne d'un statut de l'artiste sous le Second Empire, éloigné de l'image romantique du créateur libre dont est redevable le mythe constitué autour de la figure de Carpeaux.Les auteurs préparent une étude globale de l'œuvre de Bruno Chérier et de son rôle auprès de Carpeaux.

  11. Dimensionamento amostral para avaliar firmeza de polpa e cor da epiderme em pêssego e maçã Sample size to evaluate the flesh firmness and epidermis color in peach and apple

    Directory of Open Access Journals (Sweden)

    Marcos Toebe

    2011-12-01

    Full Text Available O objetivo deste estudo foi determinar o tamanho de amostra necessário para avaliar a firmeza de polpa e a cor de fundo da epiderme, em pêssego 'Eragil' e maçã 'Royal Gala'. Foram conduzidos dois experimentos, um com frutos de pêssego e outro com frutos de maçã dentro de minicâmaras de 0,23 m³. Os pêssegos foram armazenados por oito semanas a temperatura de -0,5 ºC, mais quatro dias a 20 ºC, sendo avaliadas oito formas de armazenamento (refrigerado, atmosfera controlada com diferentes concentrações de O2 e CO2, e com ou sem absorção de etileno. As maçãs permaneceram em armazenamento refrigerado durante quatro meses a 0,5 ºC, mais sete dias a 20 ºC, sendo os tratamentos compostos por doses de 1-metilciclopropeno combinados com tipos de tábuas de madeira. O número de frutos avaliados variou de 30 a 57 em pêssego e 78 a 101 em maçã. Para cada fruto foi mensurada a firmeza de polpa, com um penetrômetro manual e a cor de fundo da epiderme (luminosidade, intensidade e tonalidade de cor com colorímetro eletrônico. Posteriormente, foi determinado o tamanho de amostra necessário para a estimação da média da firmeza de polpa e da cor de fundo da epiderme. Em pêssego, 121 frutos são suficientes para a estimação da média da firmeza de polpa e da cor de fundo da epiderme com erro de estimação de 5% da média em atmosfera controlada e de 10% em armazenamento refrigerado. Em maçã, 24 frutos são suficientes para a estimação da média da firmeza de polpa e da cor de fundo da epiderme, com erro de estimação de 5% da média.The aim of this study was to determine the sample size required to asses flesh firmness and epidermis background color of 'Eragil' peaches and 'Royal Gala' apples. Two experiments were carried, one with peaches and another one with apples placed inside 0.23 m³ minichambers. The peaches were stored for eight weeks at -0.5 ºC, and then for four additional days at 20 °C, next eight kinds of storage

  12. Cinética da degradação da cor de solução hidrossolúvel comercial de urucum, submetida a tratamentos térmicos Kinetics of color degradation of water-soluble commercial annatto solutions under thermal treatments

    Directory of Open Access Journals (Sweden)

    Vera Lúcia Pupo FERREIRA

    1999-01-01

    Full Text Available Soluções comerciais hidrossolúveis de urucum foram submetidas a diferentes tratamentos de tempo/temperatura, a fim de se investigar a estabilidade da cor nestas condições. A cor foi medida em um espectrofotômetro COMCOR 1500 Plus no sistema Lab Hunter e os resultados são discutidos neste artigo, assim como as alterações de concentração do sal de norbixina e os parâmetros de cor L, a e b Hunter. Os resultados foram analisados quanto à ordem da reação e a dependência da temperatura pôde ser descrita pelo modelo de Arrhenius, com valores de energia de ativação entre 11 e 25 kcal/mol. As alterações de cor observadas foram o aumento de luminosidade do amarelo e diminuição do vermelho. As reações de degradação do sal de nobixina foram de 2a ordem e de 1a ordem para os outros parâmetros de cor.Commercial water-soluble annatto solutions were submitted to different time/temperature treatments to investigate the stability of the color in these conditions. The color was measured in a COMCOR 1500 Plus spectrophotometer in the Hunter Lab System and the results are discussed, as well as the changes in the norbixin salt concentration and L, a, b color parameters. Data were analised for order reaction and the temperature dependence being well explained by the Arrhenius model, with activation energy values between 11 and 25 kcal/mol. The changes in color showed increase on lightness and yellow color and decrease on red color. Norbixin salt degradation reaction follows the second order and for other color parameters, the first order.

  13. Influência das condições de armazenamento sobre os pigmentos cárneos e a cor do salame italiano fatiado Influence the storage conditions on the meats pigments and the color of the sliced italian salame

    Directory of Open Access Journals (Sweden)

    Cristiane Michele Marches

    2006-09-01

    Full Text Available O consumo de produtos cárneos fatiados tem aumentado nos últimos anos, particularmente os produtos curados como o salame. Os vários tipos de salame existentes são fatiados pelas indústrias de carne e/ou pelos supermercados, sem levar em conta as possíveis alterações que possam vir a ocorrer com tal procedimento. As alterações que ocorrem nos pigmentos cárneos totais e nitrosos repercutem na cor, que é detectada pelo consumidor e influencia diretamente no consumo de produtos desta natureza. O presente estudo teve como objetivo investigar o efeito da intensidade de luz, do oxigênio e da temperatura na conversão dos pigmentos cárneos em nitrosos, na quantidade de pigmentos cárneos totais e nitrosos e no índice de cor vermelha, nas fatias de salame tipo italiano. Tais fatias foram acondicionadas em quatro modelos de embalagens diferentes quanto à permeabilidade à luz e ao oxigênio e armazenadas durante 32 dias em temperaturas de 10 °C e 15 °C sob 930 LUX, continuamente, sendo estas condições similares às empregadas em gôndolas de supermercados. A quantidade dos pigmentos cárneos totais e nitrosos, o índice de cor vermelha (a*, determinado pelo método CIE* Lab, foram mensurados nas fatias no zero, 4º, 6º, 12º, 14º, 19º, 25º, 27º e 32º dia de armazenamento. Os resultados obtidos foram avaliados estatisticamente por análise de variância e teste de Tukey, adotando nível de confiança de 95% (p The consumption of sliced meat products has grown in the last few years, especially for cured products as pastrami. The different kinds of pastrami are sliced by meat industry or in the supermarkets, without concern on possible alterations that may occur in the product. The changes on the total and nitrous meat pigments influence the color of the product, which is detected by the consumer, and thus directly influences the consumption of this kind of product. The present study aimed to investigate the effect of light

  14. Effect of skin colour and selected physical characteristics on Schistosoma mansoni dependent morbidity Efeito da cor da pele e certas características físicas na morbidade dependente de Schistosoma mansoni

    Directory of Open Access Journals (Sweden)

    C. B. Cançado

    1995-12-01

    Full Text Available The effect of the colour group on the morbidity due to Schistosoma mansoni was examined in two endemic areas situated in the State of Minas Gerais, Brazil. Of the 2773 eligible inhabitants, 1971 (71.1% participated in the study: 545 (27.6% were classified as white, 719 (36.5% as intermediate and 707 (35.9% as black. For each colour group, signs and symptoms of individuals who eliminated S.mansoni eggs (cases were compared to those who did not present eggs in the faeces (controls. The odds ratios were adjusted by age, gender, previous treatment for schistosomiasis, endemic area and quality of the household. There was no evidence of a modifier effect of colour on diarrhea, bloody faeces or abdominal pain. A modifier effect of colour on hepatomegaly was evident among those heaviest infected (> 400 epg: the adjusted odds ratios for palpable liver at the middle clavicular and the middle sternal lines were smaller among blacks (5.4 and 6.5, respectively and higher among whites (10.6 and 12.9 and intermediates (10.4 and 10.1, respectively. These results point out the existence of some degree of protection against hepatomegaly among blacks heaviest infected in the studied areas.O efeito da cor na morbidade associada ao Schistosoma mansoni foi estudado em duas áreas endêmicas situadas no Estado de Minas Gerais, Brasil. Dos 2773 habitantes elegíveis, 1971 (71,1% participaram do estudo: 545 (27,6% foram classificados como brancos, 719 (36,5% como intermediários e 707 (35,9% como negros. Os sinais e sintomas dos indivíduos que eliminavam ovos de S. mansoni nas fezes (casos foram comparados aos daqueles que não apresentavam ovos do parasita neste exame (controles. As razões de chance foram ajustadas por idade, gênero, tratamento anterior para a esquistossomose, área endêmica e qualidade do domicílio. Não houve evidência de um efeito modificador da cor para a ocorrência de diarréia, sangue nas fezes ou dor abdominal. Um efeito modificador da

  15. Sexo e cor: categorias de controle social e reprodução das desigualdades socioeconômicas no brasil Sex and aolor skin: categories of social aontrol and reproduction of economic inequality in brazil

    Directory of Open Access Journals (Sweden)

    Waldemir Rosa

    2009-12-01

    Full Text Available O presente artigo objetiva apresentar algumas reflexões sobre os dados contidos no Retrato das Desigualdades de Gênero e Raça, terceira edição, acerca das desigualdades socioeconômicas e da pobreza. Tendo como linha argumentativa a tese de que, como categorias de controle social, sexo e cor configuram marcos reguladores de oportunidades sociais, apresentamos alguns dados sobre a desigualdade entre homens e mulheres e entre negros e brancos que ilustram as iniquidades de poder associadas a essa desigualdade. Ressalta-se que tais categorias são fundamentais para a compreensão da produção e da reprodução das iniquidades de poder que permeiam a sociedade brasileiraThis article presents some reflections on the data contained in the Portrait of Inequalities of Gender and Race - 3rd Edition on socioeconomic inequalities and poverty. Following a line of argument that, as categories of social control, gender and ethnicity shape regulatory frameworks of social opportunities, we present some data on inequality between men and women and between blacks and whites that illustrate the inequities of power associated with them. It is emphasized that these categories are fundamental to understand the production and reproduction of inequities of power that permeate Brazilian society

  16. Colesteatomas dos plexos coróides dos eqüídeos: observação de 14 casos Çholesteatomas of the choroid plexus of equidae: report on 14 cases

    Directory of Open Access Journals (Sweden)

    Milton Thiago de Mello

    1949-12-01

    Full Text Available O autor faz considerações sobre os colesteatomas dos plexos coróides dos ventrículos laterais do cérebro e da base do cerebelo dos eqüídeos, examinando alguns aspectos da etiologia dessas colesteatose, baseado na literatura e em suas observações pessoais. Descreve, pela primeira vez no Brasil, casos de colesteatomas em eqüídeos, em número de 14, num total de 38 solípedes examinados (38,8%. Constatou a presença da lesão em muar, fato ainda não registrado na literatura.The author discusses cholesteatomas of the choroid plexus of the lateral ventricles of the cerebrum and of the base of the cerebellum in Equidae, examining some aspects of aetiology of this cholesteatosis based on the literature and on his personal observations. He describes for the first time in Brazil, cases of cholesteatomas in Equidae, 14 in number of a total of 38 solipeds examined (36,8%. He found the presence of the lesion in the mule: a fact not yet men¬tioned in the literature.

  17. Correlation between Antioxidant Enzymes Activity and Intraerythrocyte Concentration of Fe, Mg, Zn, Cu in Pulmonary Arterial Hypertension and Cor Pulmonale in Children with Congenital Lung Disease and Cystic Fibrosis

    Directory of Open Access Journals (Sweden)

    Elena M. Vasilyeva, PhD,ScD¹

    2013-03-01

    Full Text Available Significant changes in the levels of the potential prooxidant Cu (increase and the antioxidant Zn (decrease in plasma were revealed in children having bronchopulmonary dysplasia (BPD complicated by pulmonary arterial hypertension (PAH and chronic cor pulmonale (CCP when compared with the control. The Zn / Cu ratio in the blood plasma of patients with BPD, especially in CCP, was found to be lower than in the control group (p<0.001. This could indicate the activation of the prooxidant processes; simultaneously, the total antioxidant status (AOS decreased. No significant increase in the intracellular free (“ionized” (i form of magnesium (iMg was found; in fact, the concentration of iFe in all the patient groups was higher than in the control. An increase in the iCu and iZn levels (nonprotein-bound was observed in the blood cells of the affected children. A significant increase in the glutathione peroxidase activity in the CCP patients may indicate an accumulation of organic peroxides, and partially compensate for the lesser activity of superoxide dismutase (SOD and other antioxidants. The Zn / Cu and iZn/ iCu ratios were reduced in patients with CCP when compared with patients with PD without CCP.

  18. Health inequalities based on ethnicity in individuals aged 15 to 64, Brazil, 1998 Desigualdades de saúde segundo cor em pessoas de 15 a 64 anos de idade no Brasil, 1998

    Directory of Open Access Journals (Sweden)

    Rita Barradas Barata

    2007-02-01

    Full Text Available This study aimed to analyze inequalities in health status and utilization of medical consultations and hospital services by Brazilian young and adult populations according to ethnicity. The survey analyzes a representative sample of the Brazilian population aged 15 to 64 years, except those living in the rural area of the Amazon. The prevalence of fair or poor health status was substantially higher among black men, white women, and black women. The influence of gender and ethnicity remains significant after adjusting for age and socioeconomic conditions (OR = 1.11; 1.49 and 1.86 respectively. Differences between blacks and whites decrease with age, but increase with socioeconomic status. There were 10% more medical consultations among white individuals. The differences were more striking among young people who reported good health status. For individuals with fair or poor health, no differences were observed in frequency of medical consultations between blacks and whites. There were no significant differences in hospitalization rates. With regard to health status, differences between blacks and whites were striking. However, the same was not true for utilization of health services.O objetivo foi analisar desigualdades no estado de saúde, uso de consultas médicas e internações hospitalares na população de jovens e adultos brasileiros segundo cor utilizando dados do suplemento saúde da PNAD 1998, inquérito domiciliar em amostra representativa da população brasileira de 15 a 64 anos, exceto aqueles residentes na Amazônia rural. A prevalência de estado de saúde regular ou ruim foi mais alta entre homens e mulheres negros e mulheres brancas. A influência do gênero e da cor permanece significante após ajustamento por idade e condições sócio-econômicas. As diferenças entre brancos e negros diminuem com a idade e aumentam com o nível sócio-econômico. A freqüência de consultas médicas foi 10% maior entre os brancos. As diferen

  19. Atividade da catalase e da lactato desidrogenase em tilápias submetidas a estresse de confinamento: efeito da cor do ambiente Catalase and lactate dehydrogenase activity in tilapia subjected to contention stress: effect of the background color

    Directory of Open Access Journals (Sweden)

    Elyara Maria Pereira-da-Silva

    2012-05-01

    Full Text Available Avaliaram-se os efeitos da cor do ambiente sobre o crescimento e a atividade da enzima antioxidante catalase (CAT e da lactato desidrogenase (LDH em tilápias do Nilo (n=24; 36,2±3,6g. Oito exemplares foram mortos para determinação da atividade basal das enzimas e os demais permaneceram isolados durante 14 dias sob espectro de luz branca ou azul (n=8 peixes/tratamento. A seguir os peixes foram submetidos a um estresse diário de confinamento de 90 minutos (15° ao 28° dia e pesados semanalmente para cálculo da taxa de crescimento específico (TCE. A TCE negativa confirmou que o confinamento provocou estresse nos peixes, independentemente da cor do ambiente. O aumento da atividade da LDH no músculo vermelho dos peixes mantidos sob luz branca ou azul indicou mudança do metabolismo aeróbio para anaeróbio. O estresse reduziu a atividade da CAT no músculo branco dos peixes mantidos sob a luz branca ou azul. Na musculatura vermelha, esta redução ocorreu apenas nos animais mantidos sob a luz branca. O confinamento aumenta os processos metabólicos anaeróbios e é adequado para estudos sobre os efeitos do estresse. O espectro de luz azul não evita a redução do crescimento e a demanda energética anaeróbia em situações de estresse, mas preserva a atividade da CAT, contribuindo para o bem-estar da tilápia.We assess the effects of the background color on the growth and antioxidant enzyme catalase (CAT and lactate dehydrogenase (LDH in Nile tilapia (n=24; 36.2±3.6g. Eight fish were killed for assessment of basal activity of the enzymes and the others remained isolated for 14 days under white or blue light spectrum (n=8 fish/treatment. Then each animal were subjected to a daily stress of confinement of 90 minutes (15th to 28th day and weighed to calculate the specific growth rate (SGR. The negative SGR confirmed that the confinement stressed in fish, regardless of the background color. The increased activity of LDH in red muscle of fish

  20. Considerações sobre o dilema entre cor/raça/mestiçagem e ações afirmativas no Brasil / Consideration on the dilemma between color/race/miscegenation and affirmative action in Brazil

    Directory of Open Access Journals (Sweden)

    Mozart Linhares da Silva

    2010-01-01

    Full Text Available O artigo problematiza as abordagens racialistas e não-racialistas que marcam o debate sobre ações afirmativas no Brasil tomando a miscigenação como eixo norteador de ambas as posturas político-teóricas. Propõe uma crítica às abordagens que visam a racialização das identidades no país bem como às abordagens dos intelectuais que, em nome das idiossincrasias locais ou mesmo dos princípios igualitaristas, procuram contornar as políticas diferencialistas. É na tensão entre as políticas de redistribuição e reconhecimento que o texto assenta, portanto, a análise sobre os dilemas entre cor/raça/mestiçagem e políticas de ações afirmativas no Brasil.Abstract The article discusses the racialists and non-racialist approaches that mark the debate on affirmative action’s in Brazil taking miscegenation as a guideline for both political andtheoretical stances. It proposes a critique of the approaches to the racialization of the identities in the country as well as the approaches of the intellectuals who, on behalf of local idiosyncrasies or even egalitarian principles, try to avent differential policies. It is the tension between the redistribution and recognition policies that the text is based on, therefore, the analysis of the dilemmas between color/race/miscegenation and affirmative action policies in Brazil.

  1. Violência, etnia e cor: um estudo dos diferenciais na região metropolitana de Salvador, Bahia, Brasil Violence, ethnic group, and skin color: a study of disparities in the metropolitan region of Salvador, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Ceci Vilar Noronha

    1999-04-01

    Full Text Available O objetivo do presente estudo é analisar a distribuição das distintas modalidades de violência - estrutural, institucional, interpessoal e derivada da delinqüência - nos três grupos de cor mais representativos da sociedade baiana: brancos, mulatos e negros. O estudo compara os níveis de vitimação de indivíduos brancos, negros e mulatos com suas próprias avaliações da eficiência das instituições de controle do crime, procurando identificar como isso se relaciona com a adoção de atitudes e normas autoritárias pelos mesmos sujeitos. Os dados analisados são provenientes do Estudo Multicêntrico sobre Atitudes e Normas Culturais face à Violência (projeto ACTIVA e compreendem uma amostra de 1384 pessoas residentes na região metropolitana de Salvador. A investigação foi desenhada como um estudo de corte transversal, com entrevistas realizadas nos domicílios, no período de setembro a dezembro de 1996. A seleção da amostra se processou em três etapas: primeiro foram selecionadas, de modo aleatório, as áreas residenciais, seguindo uma amostragem sistemática dos domicílios em cada área do sorteio; por fim, o sujeito a ser entrevistado foi escolhido, também por sorteio. Para a coleta de dados foi utilizado o questionário desenhado para o estudo ACTIVA e testado em estudo piloto. Os resultados indicam uma distribuição desigual da violência estrutural que recai, principalmente, sobre indivíduos de pele negra; o perfil por grupos de cor para a violência interpessoal e institucional revelou-se indistinto. A violência da delinqüência atinge os brancos e os negros na mesma intensidade. O descrédito na eficiência das polícias civil e militar, da justiça e do sistema carcerário é muito alto e é generalizado para os três grupos de cor. Além disso, poucas diferenças foram encontradas entre os grupos com relação a atitudes e normas autoritárias. Com base nos resultados, é possível concluir que existe risco

  2. Caracterização de efluente têxtil e avaliação da capacidade de remoção de cor utilizando o fungo Lasiodiplodia theobromae MMPI

    Directory of Open Access Journals (Sweden)

    Everton Pizato

    2017-04-01

    Full Text Available RESUMO Os processos industriais de produção têxtil têm como característica o uso de grandes volumes de água durante as etapas de lavagem e tingimento dos tecidos, resultando em efluentes com enorme diversidade e complexidade química. A presença de corantes dissolvidos é bastante visível e problemática, considerando sua recalcitrância e cinética de degradação lenta. Neste trabalho, o fungo Lasiodiplodia theobromae MMPI foi avaliado quanto à capacidade de descoloração de efluente industrial têxtil. Os ensaios foram conduzidos em biorreator de bancada (5 L com tempo de incubação de 192 horas. A eficiência de descoloração variou de 19,52% (24 h a 91,26% (168 h e a produção de biomassa micelial variou de 1,23 g.L-1 (24 h a 7,60 g.L-1 (168 h. Produção de exopolissacarídeo (EPS também foi observada, com quantidades variando de 2,84 g L-1 em 24 h a 4,28 g.L-1 em 48 h. A caracterização do efluente industrial indicou valores de alguns parâmetros de controle fora dos padrões de lançamento exigidos pela legislação brasileira, com elevada demanda química de oxigênio (DQO (659 mg.L-1 e demanda bioquímica de oxigênio (DBO5 (328 mg.L-1. A análise de toxicidade utilizando o microcrustáceo Artemia salina demonstrou que a concentração de efluente bruto que causou a mortalidade de 50% dos organismos (CL50 foi de aproximadamente 14,72% (v/v e ao final do tratamento foi de 4,98% (v/v. Embora o fungo não tenha sido hábil na detoxificação biológica do efluente, ele apresentou resultados promissores quanto à capacidade de remoção de cor, demonstrando potencial de uso em processos auxiliares de tratamento de efluente industrial têxtil visando descoloração.

  3. The color of illumination affects the stress response of jundiá (Rhamdia quelen, Quoy & Gaimard, Heptapteridae A cor da iluminação afeta a resposta ao estresse em jundiá (Rhamdia quelen, Quoy & Gaimard, 1824, Heptapteridae

    Directory of Open Access Journals (Sweden)

    Leonardo José Gil Barcellos

    2006-08-01

    Full Text Available This paper provides the first data about physiological responses to stress in jundiá (Rhamdia quelen exposed to different light colours. Jundiá is a species for fish production in the southern part of South America - and suitable for any region with a temperate or subtropical climates. In order to develop a light management for jundiá fingerlings during indoor maintenance and to understand the relationship between welfare and light colour in the jundiá, fingerlings were exposed to white, blue and green light. At the 10th day of light exposure an acute stressor was imposed. One hour after the application of the stressor, fish were sampled. Stress was assessed by means of cortisol determination. Our results show that green light seems to be the worst alternative to illuminate jundiá indoor experimentation facilities, or even fish transportation. The results also suggests that colour affects the stress response of jundia, and may be usefull for the management of this species.Este artigo traz os primeiros resultados sobre a resposta ao estresse em jundiá (Rhamdia quelen expostos a diferentes cores de luz. O jundiá é uma espécie para produção no sul da América do Sul - sendo assim apta a cultivo em qualquer região de clima temperado e subtropical. Com o objetivo de desenvolver um manejo de luz para o jundiá durante sua manutenção em tanques internos e de entender a relação entre as cores de luz e o bem-estar da espécie, alevinos foram exposto por 10 dias à luz branca, azul e verde. No 10° dia de exposição às diferentes cores de luz, um estressor agudo foi imposto. Uma hora após a aplicação do estressor, os peixes foram amostrados e a resposta ao estresse medida por meio da determinação da concentração sérica de cortisol. Nossos resultados mostraram que a luz verde parece ser a pior alternativa para iluminar instalações internas ou de transporte de jundiás. Os resultados também sugerem que a cor da luz afeta a

  4. Single institutional retrospective analysis: treatment of choroidal melanomas with cobalt-60 brachytherapy Análise retrospectiva uni-institucional: tratamento de melanomas de coróide com braquiterapia utilizando cobalto-60

    Directory of Open Access Journals (Sweden)

    Antônio Cássio Assis Pellizzon

    2004-06-01

    Full Text Available PURPOSE: To evaluate the outcome of patients with choroidal melanoma treated with conservative therapy with brachytherapy (episcleral Co-60 plaque therapy at the "Hospital do Cancer" São Paulo, Brazil. METHODS: We evaluated 102 patients consecutively treated from January, 1999 to June, 1999. Median age, maximum tumor base diameter and apex size were 55.5 years, 9.75 mm and 5 mm, respectively. Doses at the base of the tumor, including 1 mm of sclera, ranged from 157 to 487 Gy (median 284.5 Gy and to the apex from 37 to 220 Gy (median 106 Gy. RESULTS: The crude eye preservation rate with conservative therapy alone was 78.5%. Five-year overall actuarial survival rate was 92.2% and eye conservation rate was 78%. Side effects were mostly an uncomplicated retinopathy in 39/102 patients (38.2%; macular degeneration or scarring led to poor central vision in 31/102 patients (30.3% of cases. CONCLUSION: Our experience with cobalt-60 plaque brachytherapy achieved a satisfactory rate of local tumor control, despite the oversized base diameters of treated tumors.OBJETIVOS: Para avaliar o resultado de tratamento pacientes portadores de melanoma de coróide tratados com braquiterapia (placas episclerais de Co-60 no Hospital do Câncer, São Paulo, Brasil. MÉTODOS: Foram avaliados 108 pacientes tratados consecutivamente de janeiro de 1995 a junho de 1999, com idade mediana de 55,5 anos, diâmetro da base do tumor e altura máximos 9,75 mm e 5 mm, respectivamente. As doses na base do tumor, incluindo 1 mm de esclera variaram de 157 a 487 Gy (mediana 284,5 Gy e para o ápice de 37 até 220 Gy (mediana 106 Gy. RESULTADOS: A taxa de preservação ocular foi 78,5%, com sobrevida atuarial global em cinco anos, e a taxa de conservação ocular atuarial foram 92,2% e 78%, respectivamente. Os principais efeitos colaterais relacionados ao tratamento foram retinopatia em 39/102 (38,2% pacientes e degeneração macular, levando a déficit visual central em 31/102 (30

  5. Los coríxidos (hemiptera, heteroptera del estanque piscícola denominado “JC” en Soyaniquilpan de Juárez, Estado de México

    Directory of Open Access Journals (Sweden)

    G. Contreras Rivero

    2002-01-01

    Full Text Available Los Corixidae son chinches acuáticas de importancia económica, utilizados como alimento humano, para peces y aves, entre otros. Sus aspectos ecológicos en México son poco conocidos por lo que el objetivo es señalar algunos de ellos. Se realizaron once muestreos mensualmente de octubre de 1995 a agosto de 1996 en el estanque piscícola “JC” en el Estado de México. Se ubicaron dos estaciones de muestreo y en cada una se midió profundidad, transparencia, temperatura, oxígeno, pH, conductividad, dureza y alcalinidad. Los coríxidos se capturaron con una red de cuchara rectangular. Se registraron cuatro especies: Trichocorixella mexicana, Graptocorixa abdominalis, Krizousacorixa femorata y Corisella edulis. La especie T. mexicana vio incrementada su densidad por la transparencia (0.27 m, la profundidad (0.78 m y el oxígeno (7.03 mg⋅L-1 y afectada por un descenso en la profundidad (0.17 m y un incremento en la temperatura (20.7 °C. G. abdominalis aumentó su densidad por la transparencia (0.28 m; descendiendo por el pH (9.0, la conductividad (132.5 µmhos⋅cm-1, la profundidad (0.01 m, la temperatura (13.4 °C y el oxígeno (8.72 mg⋅L-1. K. femorata aumentó su densidad por los mismos parámetros que T. mexicana y su descenso se debió al incremento en la dureza (100 mg CaCO3⋅L-1. C. edulis solamente se presentó cuando el pH fue ligeramente ácido (6.9. Se concluye que la densidad de los Corixidae está en relación con las fluctuaciones de los parámetros ambientales del estanque “JC”.

  6. Use of colour parameters for roasted coffee assessment Utilização dos parâmetros de cor para avaliação do café torrado

    Directory of Open Access Journals (Sweden)

    Natalina Cavaco Bicho

    2012-09-01

    Full Text Available Fast and non-destructive indicators were evaluated as tools to measure the technological quality of Arabica and Robusta coffee. Accordingly, considering the roasting intensity in highly valuable commercial samples, volume, mass, apparent density, moisture, total ash, ash insoluble in hydrochloric acid, and ether extract were characterized. The chromatic parameters L*, C*, Hº were measured using illuminants D65 and C. It was found that in roasted coffee beans, the parameters L*, C*, Hº, and coordinate b* had an antagonist interaction due to an increase in the roasting intensity, whereas after milling, only L* and Hº decreased progressively. Considering that the parameters L* and Hº followed similar patterns using both illuminants, D65 and C, it can be concluded that they are appropriate to evaluate coffee colour changes during roasting, enabling a relationship with coffee quality.Avaliaram-se indicadores não destrutivos e de execução rápida, para aferir a qualidade tecnológica de cafés Arábica e Robusta. Neste contexto, considerando a intensidade da torra em amostras com elevado interesse comercial, caracterizaram-se o volume, massa, densidade aparente, umidade, cinzas totais e insolúveis em ácido clorídrico e do extrato etéreo. Foram então analisados os parâmetros cromáticos L*, C*, Hº utilizando os iluminantes D65 e C. Verificou-se que em grãos de café torrado os parâmetros L*, C*, Hº e a coordenada b* mostraram uma interação antagônica face ao acréscimo da intensidade da torra, enquanto, após a moagem, apenas o L* e o Hº decresceram progressivamente. Considerando que a coordenada L* não variou significativamente com a aplicação dos dois iluminantes, concluiu-se que este parâmetro é o mais adequado para estudar a evolução da cor durante a torra, permitindo ainda estabelecer uma correlação com a qualidade.

  7. TELLUS_GLDAS_MONTHLY_TXT_COR:1

    Data.gov (United States)

    National Aeronautics and Space Administration — The land water content contained in this dataset were generated from The Global Land Data Assimilation System (GLDAS). GLDAS outputs land water content by using...

  8. TELLUS_GLDAS_MONTHLY_NC_COR:1

    Data.gov (United States)

    National Aeronautics and Space Administration — The land water content contained in this dataset were generated from The Global Land Data Assimilation System (GLDAS). GLDAS outputs land water content by using...

  9. An interesting case of cor pulmonale

    Directory of Open Access Journals (Sweden)

    Bagrecha Manish V, Kunkulol Rahul R

    2013-01-01

    Full Text Available A 14 yrs old boy presented with a history of breathlessness since 1 yr which had increased from 2 days, cough with expectoration and pedal edema since 7 days. In the past patient had history of kyphoscoliosissince birth and had a history of repeated URTI. On examination he had tachycardia, tachypnea, raised JVP, kyphoscoliosis, bilateral pitting edema. Respiratory auscultation revealed bilateral fine crepitations and wheezes. On investigation haemoglobin: 14.6, T.L.C: 20,000,chest X-ray: kyphoscoliosis with cardiomegaly. Clinical diagnosis of corpulmonale due to kyphoscoliosis was achieved and was confirmed with 2D echo. ECG showed RVH. The patient was treated with oxygen, diuretics, antibiotics, bronchodilators. Patient improved and was discharged on bronchodilators and was asymptomatic on follow up.

  10. A rare cause for acute cor pulmonale.

    Science.gov (United States)

    Rajasekharan, C; Ganga, V

    2011-05-01

    A number of diseases may cause right atrial mass. Primary cardiac tumors range from 0.002 to 0.25%. Intracardiac manifestation and pulmonary embolism of hepatocellular carcinoma (HCC) is a very rare finding and uncommon even at autopsy. Here we describe the case of a 32-year-old Asian man who was referred for shortness of breath lasting for a month, along with unproductive cough. He was a manual laborer with a history of diabetes, alcoholism, and smoking. Clinically he was diagnosed as having pulmonary embolism. Echocardiogram showed a mass in the right atrium. Magnetic resonance imaging showed that he had a large mass in the right atrium extending down into the inferior vena cava. Further evaluation showed that he had chronic liver disease with portal hypertension and was hepatitis B surface antigen-positive, indicating hepatitis B infection. He underwent excision of the mass, and the pathological report showed metastasis of HCC with multiple vascular emboli in the lungs. As this is the second reported case of this kind in the literature, we highlight the need of screening at least 6-monthly all patients with chronic liver disease, hepatitis B and C virus infection for the early detection of HCC.

  11. A Rare Cause for Acute Cor Pulmonale

    Directory of Open Access Journals (Sweden)

    C. Rajasekharan

    2011-06-01

    Full Text Available A number of diseases may cause right atrial mass. Primary cardiac tumors range from 0.002 to 0.25%. Intracardiac manifestation and pulmonary embolism of hepatocellular carcinoma (HCC is a very rare finding and uncommon even at autopsy. Here we describe the case of a 32-year-old Asian man who was referred for shortness of breath lasting for a month, along with unproductive cough. He was a manual laborer with a history of diabetes, alcoholism, and smoking. Clinically he was diagnosed as having pulmonary embolism. Echocardiogram showed a mass in the right atrium. Magnetic resonance imaging showed that he had a large mass in the right atrium extending down into the inferior vena cava. Further evaluation showed that he had chronic liver disease with portal hypertension and was hepatitis B surface antigen-positive, indicating hepatitis B infection. He underwent excision of the mass, and the pathological report showed metastasis of HCC with multiple vascular emboli in the lungs. As this is the second reported case of this kind in the literature, we highlight the need of screening at least 6-monthly all patients with chronic liver disease, hepatitis B and C virus infection for the early detection of HCC.

  12. Reator anaeróbio tipo UASB conjugado com processo Fenton para remoção de cor e demanda química de oxigênio de água residuária sintética de indústria têxtil

    Directory of Open Access Journals (Sweden)

    Emília Maria Alves Santos

    Full Text Available RESUMO A contaminação por despejos de efluentes industriais têxteis tem sido uma preocupação emergente de pesquisadores e ambientalistas, pois esses apresentam composição extremamente heterogênea e grande quantidade de material tóxico e recalcitrante, o que dificulta seu tratamento. Durante o processamento têxtil, uma ampla gama de corantes é liberada e alguns desses, como os azo corantes, que se caracterizam pela função azo (-N=N- ligada a grupos aromáticos e podem ser tóxicos, carcinogênicos e/ou mutagênicos. Em vista disso, esta pesquisa teve como principal objetivo avaliar os benefícios da utilização de um reator anaeróbio tipo reator anaeróbico de fluxo ascendente com manta de lodo (UABS, seguido de processo oxidativo avançado (POA do tipo Fenton na degradação de cor e demanda química de oxigênio (DQO de efluente sintético de indústria têxtil. Com os resultados, foram verificadas remoções de DQO em torno de 82,0% para o reator UASB e de 95,6% para o conjunto. A cor alcançou 96,1% de remoção no reator UASB e 100,0% ao final do processo.

  13. Avaliação da cristalização de mel utilizando parâmetros de cor e atividade de água Evaluation of honey crystallization from the colour and water activity parameters

    Directory of Open Access Journals (Sweden)

    Alini Mari Kuroishi

    2012-03-01

    Full Text Available O mel é um dos edulcorantes mais antigos utilizados pelo homem, sendo composto principalmente de monossacarídeos, como a glicose e a frutose, responsáveis em parte pela sua cristalização. A cristalização varia segundo diversos fatores, como a concentração de açúcares, o teor de água na sua composição natural, a procedência floral do néctar, o manuseio durante seu processamento, bem como as condições de estocagem. O presente trabalho teve como objetivo avaliar o efeito da temperatura e da incorporação de cristais de mel na cristalização do mel utilizando como parâmetro de acompanhamento a cor, por meio da determinação do Índice de Brancura (IB e variação da luminosidade (∆L*, e a atividade de água. Utilizou-se um delineamento experimental fatorial 2², tendo-se como variáveis o percentual de cristais de mel adicionado e a temperatura de armazenamento. Apenas as amostras armazenadas à temperatura de 11 e 21 °C cristalizaram, sendo mais evidente a cristalização da amostra armazenada em 11 °C, que foi adicionada de 5% de cristais de mel. O aumento da atividade de água e o aumento no Índice de Brancura (IB, assim como o ∆L*, foram correlacionados com a cristalização das amostras. A maior variação obtida para os valores de ∆L* encontram-se na região de temperatura de armazenamento de 11 °C, na qual as amostras cristalizaram mais rapidamente.Honey is one of the oldest sweeteners used by man, composed mainly of monosaccharides such as glucose and fructose, partially responsible for its crystallization. Honey crystallization depends on several factors, such as the sugar concentrations, natural percentage of water, the floral origin of the nectar, handling during processing and the storage conditions. The present work aimed to evaluate the effect of temperature and of the incorporation of honey crystals on honey crystallization, using the colour (as determined by the Whiteness Index - WI and changes in the

  14. Nèg Blanc sa a (Aquela negra branca – desafiando as categorias de cor, nacionalidade e pertença a partir de um olhar afro-brasileiro sobre o Haiti

    Directory of Open Access Journals (Sweden)

    Renata de Melo Rosa

    2016-11-01

    Full Text Available Resumo  Este artigo tem como objetivo analisar a centralidade da categoria de pessoa no Haiti contemporâneo, a qual se funda a partir dos sentidos contextuais atribuídos à noção de nèg, (que em tradução livre para o português pode ser entendida como “negro/a” que antecede e funda, ao mesmo tempo, a categoria de pessoa. No entanto, mesmo que a categoria de pessoa no Haiti se ancore em uma nomenclatura “racial”, nèg não é uma categoria necessariamente atrelada à cor da pele, mas à qualidade da pertença de cada sujeito à nação haitiana. Identificar-se e ser identificado como um “nèg” atualiza, no processo identitário e no diálogo inter-subjetivo, diacríticos importantes, cujos sentidos são dados coletiva e contextualmente na rede de significados tecidas no contexto haitiano. Assim, pela natureza contextual e por sua constante dinâmica, é possível que uma “pessoa” que, aos olhos ocidentais, possa se assemelhar com o que nós entendemos como um/a “negro/a” no Brasil, no Haiti esta mesma “pessoa” pode não estar imediatamente identificada como um nèg ou como uma pessoa que  “pertença” ao Haiti. Em outras palavras, é preciso que cada nèg (para continuar sendo nèg e, portanto, “pessoa” atualize, de acordo com os contornos da cultura haitiana que inscrevem um nèg, as diversas obrigações rituais de pertença a esta categoria. Vista desta perspectiva, a categoria nèg pode ser ritualizada por um (a haitiano (a branco (a, desde que os rituais de pertença à nação também sejam atualizados, tornando o sujeito em um (a Nég Blanc (negro branco, expressão que dá título a este artigo. Por último, esta reflexão propõe que a categoria nèg como sinônimo da categoria de pessoa é uma contra narrativa às tentativas de inferiorização racial vigentes no período colonial francês. Palavras chave: nèg; noção de pessoa; Haiti; nação, categorias de cor. Nèg Blanc sa a (Aquella negra

  15. Does the way I see you affect the way I see myself? Associations between interviewers' and interviewees' "color/race" in southern Brazil Como te percebo afeta o modo como me vejo? Relações da "cor/raça" de entrevistadores e de entrevistados no Sul do Brasil

    Directory of Open Access Journals (Sweden)

    João Luiz Bastos

    2009-10-01

    Full Text Available This study assessed the associations between female interviewers' self-classified "color/race" and participants' self- and interviewer-classified "color/race". A cross-sectional study was carried out among adult individuals living in Pelotas, southern Brazil. Associations were examined by means of contingency tables and multinomial regression models, adjusting for interviewees' socioeconomic and demographic factors. Individuals aged > 40 years were 2.1 times more likely to classify themselves as brown (versus white when interviewed by black (as compared to white interviewers. Participants in the same age group were 2.5 times less likely to classify themselves as black (versus white, when interviewed by black interviewers. These differences were even greater among men 40 years or older. Compared to white interviewers, black female interviewers were 2.5 times less likely to classify men aged > 40 years as black. These results highlight the complexity of racial classification, indicating the influence of the interviewer's physical characteristics on the interviewee's "color/race".Avaliou-se a relação entre "cor/raça" de entrevistadoras, auto e heteroclassificação de "cor/raça" dos entrevistados. Foi realizado um estudo com indivíduos adultos de Pelotas, Rio Grande do Sul, Brasil. As associações foram verificadas com tabelas de contingência e modelos multinomiais, ajustando-se para variáveis sócio-econômicas e demográficas dos entrevistados. Indivíduos com > 40 anos tiveram uma chance 2,1 vezes maior de se classificarem como pardos do que como brancos, quando abordados por entrevistadoras pretas, em relação às brancas. Entrevistados dessa mesma faixa etária apresentaram 2,5 vezes menos chances de se classificarem como pretos do que como brancos, ao serem abordados por entrevistadoras pretas. Essas diferenças foram mais expressivas entre homens de > 40 anos. Entrevistadoras pretas tiveram chance 2,5 vezes menor de classificar

  16. Cor, capacidade de retenção de água e maciez da carne de cordeiro maturada e injetada com cloreto de cálcio Colour, water holding capacity and tenderness of lamb aged and injected with calcium chloride

    Directory of Open Access Journals (Sweden)

    N.M.B.L. Zeola

    2007-08-01

    Full Text Available Os músculos Biceps femoris, Longissimus e Triceps brachii submetidos aos efeitos do tempo de maturação e da injeção com cloreto de cálcio de cordeiros Morada Nova foram estudados quanto às características de cor, capacidade de retenção de água e maciez. Os cordeiros foram abatidos ao atingirem 25kg de peso vivo. Os músculos apresentaram diferenças na cor (luminosidade-L*, teor de vermelho-a* e teor de amarelo-b* 24 horas após o abate. A maturação tendeu a escurecer a carne. O cloreto de cálcio não modificou a cor das carnes provenientes dos músculos Longissimus e Triceps brachii, entretanto as do Biceps femoris apresentaram-se mais vermelhas quando receberam cloreto de cálcio. Quanto à capacidade de retenção de água, a maturação afetou as carnes do Triceps brachii, mas não influenciou as carnes dos músculos Biceps femoris e Longissimus. O cloreto de cálcio não modificou a capacidade de retenção de água dos músculos avaliados. A maturação influiu sobre a maciez do Biceps femoris e do Longissimus.Biceps femoris, Longissimus and Triceps brachii muscles from Morada Nova lambs were submitted to ageing and calcium chloride injection. Colour, water holding capacity and tenderness were studied. Lambs were slaughtered weighting 25kg.. The muscles presented differences in colour (lightness-L*, redness-a* and yellowness- b* 24 hours after rigor mortis instalation. Ageing intensified redness of the meats. Calcium chloride did not modify the colour of Longissimus and Triceps brachii, however, Biceps femoris became more redness after receiving calcium chloride. In relation to water holding capacity, ageing affected meats from Triceps brachii. However, it did not affect Biceps femoris and Longissimus. The calcium chloride didn't modify the water holding capacity of the muscles. Ageing influenced tenderness of Biceps femoris and Longissimus.

  17. Variação da cor e propriedades cerâmicas com o aumento da temperatura de queima de uma argila proveniente da formação Corumbataí, região de Piracicaba, SP Variation of color and ceramic properties with the increase of temperature of clay's firing from the Corumbataí formation, region of Piracicaba, SP

    Directory of Open Access Journals (Sweden)

    C. D. Roveri

    2007-12-01

    Full Text Available Objetivando compreender a influência do ferro contido na illita, presente na formação Corumbataí, na cor de queima de produtos cerâmicos selecionou-se uma amostra de cor cinza esverdeado claro, dominantemente illítica e com porcentagem de óxidos e hidróxidos de ferro relativamente baixo, com base em estudos petrográficos, mineralógicos e químicos. Para os testes cerâmicos, os corpos de prova foram queimados em forno de queima rápida de laboratório nas temperaturas de 900 ºC, 950 ºC, 1000 ºC, 1050 ºC, 1075 ºC e 1100 ºC, com taxa de aquecimento de 40 ºC/min, sendo um conjunto de corpos de prova queimado a 950 ºC, porém com taxa de aquecimento de 20 ºC/min, com o intuito de verificar a influência do tempo de queima na coloração das peças cerâmicas. O tempo de queima mostrou não interferir significativamente na alteração da cor e os corpos de prova apenas apresentaram alterações significativas a partir da temperatura de 1000 ºC, adquirindo, respectivamente os matizes: laranja, vermelho e marrom escuro. A mudança de cor foi acompanhada em intensidade equivalente pela retração linear de queima, pela absorção de água e módulo de ruptura por flexão.The objective of this paper is to understand the influence of the iron contained in the illite, present in the Corumbataí formation, in the color of firing of ceramic products. A sample was selected, with a gray color clearly, with illite domination, hydroxide and oxide percentage and relatively low iron, with basis of petrographics, mineralogical and chemical studies. For the ceramic essays, the test bodies were fired in a fast firing kiln of laboratory in the temperatures of 900 ºC, 950 ºC, 1000 ºC, 1050 ºC, 1075 ºC and 1100 ºC, with heating rate of 40 ºC/min, a set of bodies test was fired at 950 ºC, however with heating rate of 20 ºC/min, for the checking of the influence of the time of firing range in the coloration of the ceramic plates. The time of

  18. Avaliação da cor, corrosão e rugosidade superficial do titânio c.p., ligas metálicas e resina acrílica termopolimerizável sob a ação de soluções higienizadoras

    OpenAIRE

    Letícia Resende Davi

    2010-01-01

    A higienização das próteses parciais ou totais removíveis é fundamental para a durabilidade do tratamento e prevenção de patologias orais. O objetivo deste estudo foi avaliar o efeito de agentes higienizadores de prótese na cor, corrosão e rugosidade superficial do titânio c.p., ligas metálicas e resina acrílica termopolimerizável, simulando um período de 180 dias de higienização. Espécimes em formato de discos (12 mm x 3 mm) foram confeccionados em: titânio comercialmente puro (Tritan - Ti c...

  19. Vasculopatia polipoidal idiopática da coróide: aspectos extremos da evolução da doença em um paciente - Relato de caso Idiopathic polypoidal choroidal vasculopathy: its extreme aspects in one patient - Case report

    Directory of Open Access Journals (Sweden)

    Ieda Maria Alexandre Barreira

    2005-04-01

    Full Text Available O artigo descreve um caso de vasculopatia polipoidal idiopática da coróide (VPIC e demonstra o papel relevante da indocianinografia no diagnóstico diferencial com outras causas de neovascularização subretiniana, particularmente degeneração macular relacionada à idade (DMRI, bem como avalia os aspectos extremos na evolução da doença em um único paciente. Paciente de 54 anos, sexo masculino, cor parda, com queixas de baixa de acuidade visual súbita em OD, foi submetido a exame oftalmológico, pelo qual se constatou hemorragia vítrea em OD e, posteriormente, descolamento sero-hemorrágico do epitélio pigmentário da retina em OE. A angiofluoresceinografia e indocianinografia mostraram quadro compatível com vasculopatia polipoidal idiopática da coróide. O paciente foi submetido a vitrectomia via pars plana em OD e foi acompanhado por período de 5 meses, evoluindo com perda de visão secundária a descolamento de retina e cicatriz macular disciforme em OD. No olho contralateral, ocorreu involução da vasculopatia com preservação de acuidade visual 20/25. A vasculopatia polipoidal idiopática da coróide é entidade clínica cujas anormalidades do fundo de olho se sobrepõem às manifestações da degeneração macular relacionada à idade exsudativa. A indocianinografia é de vital importância no diagnóstico diferencial entre as duas doenças que tem evolução e prognóstico distintos. Além disso, consideramos este caso muito ilustrativo pelas diferentes nuances com que a doença se manifestou e evoluiu em um único paciente.To describe a case of idiopathic polypoidal choroidal vasculopathy and the role of indocyanine green angiography findings in the differential diagnosis of exsudative maculopathies, particularly with age-related macular degeneration, and the extreme evolution of idiopathic polypoidal choroidal vasculopathy in one patient. A patient with vitreous hemorrhage was examined and evaluated by fluorescein and

  20. Avaliação da alteração de cor e rugosidade média superficial de resinas acrílicas usadas em base de próteses após imersão em desinfetantes químicos e bebidas

    OpenAIRE

    Flávio Henrique Carriço Nogueira Fernandes

    2009-01-01

    Pacientes submetidos a procedimento protéticos estão expostos a microorganismos patogênicos podendo ocorrer desenvolvimento de doenças e infecção cruzada entre pacientes e equipe odontológica.As próteses devem ser desinfetadas com substâncias que não provoquem alterações nas propriedades mecânicas e físicas principalmente em associação com a ingestão de bebidas com teor alcoólico ou baixo pH. O objetivo desse estudo foi avaliar a rugosidade média superficial (Ra) e estabilidade de cor de resi...

  1. Alterações na cor e no grau de floculação de um Latossolo Vermelho-Escuro sob cultivo contínuo de cana-de-açúcar Alterations of the colour and of the degree of floculation of a Dark-Red Latosol under conditions of continuous cultivation of sugar cane

    Directory of Open Access Journals (Sweden)

    Renato de Mello Prado

    2001-01-01

    Full Text Available Objetivou-se avaliar o grau de modificação de algumas propriedades físicas e da cor do horizonte superficial de um Latossolo Vermelho-Escuro textura média, submetido ao cultivo contínuo com cana-de-açúcar durante 25 anos, em Jaboticabal, SP. Os tratamentos foram constituídos por dois tipos de uso do solo, ou seja, ausência de cultivo (vegetação nativa e cultivo intenso com cana-de-açúcar e por três profundidades no perfil, 0-10, 10-20 e 20-30cm. O cultivo intenso e contínuo alterou a cor do solo na camada de 0-10cm de 2,5YR 2,5/4 na ausência de cultivo para 2,5YR3/4 e degradou a macroestrutura, reduzindo o grau de floculação da argila do solo.The study aimed at assessing the degree of modification of certain physical properties and of the colour of the superficial soil layer of a Dark-Red Latosol of medium texture, subjected to the continuous cultivation of sugar cane during 25 years in Jaboticabal, SP, Brazil. The treatments consisted of two types of soil use, i.e. absence of cultivation (native vegetation and intense cultivation with sugar cane, at three depth levels of 0-10, 10-20 and 20-30 cm. The continuous cultivation altered the colour of the level 0-10 cm from 2.5YR2.5/4 (absence of cultivation to 2.5YR3/4, and impaired the macro structure and lessened the degree of flocculation of the soil's clay.

  2. Efeito da cor do ambiente sobre o estresse social em tilápias do Nilo (Oreochromis niloticus Effect of background color on the social stress of Nile tilapia (Oreochromis niloticus

    Directory of Open Access Journals (Sweden)

    Giovana Krempel Fonseca Merighe

    2004-08-01

    Full Text Available Estudaram-se as respostas comportamentais e fisiológicas de juvenis de tilápia do Nilo (Oreochromis niloticus submetidos a diferentes cores de ambientes e situações sociais. Os animais foram mantidos isolados em aquários recobertos com papel-cartão colorido, compondo cinco tratamentos (preto, verde, marrom, azul e branco.Utilizando-se filmagens semanais realizadas em etapas distintas e alternadas (isolamento e presença de um espelho, registraram-se os seguintes parâmetros: distribuição na coluna d'água, coloração, atividade locomotora, confrontos agonísticos, posição da nadadeira dorsal e postura. Para quantificação dos níveis plasmáticos de glicose, triglicerídeos, proteínas totais e cortisol, coletaram-se amostras de sangue após cada filmagem. As médias obtidas foram analisadas estatisticamente pelo método não-paramétrico de Kruskal-Wallis. Os peixes mantidos nos ambientes preto e verde apresentaram baixas freqüências de confrontos agonísticos, enquanto aqueles mantidos no ambiente branco, altas freqüências, porém com redução do padrão ameaça e não alterando sua locomoção. Animais submetidos às cores marrom e azul apresentaram as mais altas freqüências de comportamentos agonísticos e maior atividade locomotora. Os peixes permaneceram em todos os tratamentos com a coloração clara, ocupando, com maior freqüência, a região inferior da coluna d'água. Não foram observadas diferenças significativas para as concentrações de glicose, triglicerídeos e proteínas totais entre os tratamentos, porém obteve-se elevado nível de cortisol para os animais mantidos nos ambientes azul e marrom, quando submetidos à reflexão da própria imagem em espelho. Estes resultados mostraram que existe influência da cor do ambiente sobre o estresse social, em particular nas interações agonísticas entre coespecíficos e na concentração do hormônio cortisol. Concluiu-se que as cores verde e preta s

  3. Pobreza, raça e cor da pele: Percepções e relações entre crianças nos espaços escolares

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Salum Moreira

    2015-11-01

    tratamento desigual, modelado por discriminações através de chacotas, xingamentos, apelidos depreciativos, separações, entre outros, vivenciados na escola. Essas crianças eram aluno(as do 5º ano do ensino fundamental, em uma escola pública localizada em cidade de médio porte, no interior do Estado de São Paulo. Visou-se a empreender uma análise das práticas de diferenciação de classe e raciais que hierarquizam, discriminam e excluem determinadas crianças, realizadas por adultos e/ou pelas próprias crianças. O estudo, do tipo etnográfico, fez uso de relatos, de questionário sobre denominação e classificação de cor/raça, respondido pelas crianças em sala de aula, levantamento socioeconômico, observações das relações vivenciadas em diferentes ambientes da escola e de entrevista semiestruturada com as crianças e professora. Entre outros resultados, confirmou-se que as crianças negras, pretas e pardas, pobres e com história de fracasso escolar sofrem maiores discriminações na escola, por parte da professora e das demais crianças. Além disso, constatou-se que mesmo entre aquelas que são pobres e/ou negras, ocorre a construção de fronteiras para a distinção que cada um faz de si em relação aos demais. Portanto, a pesquisa proporcionou reconhecer a diversidade de posições em relação ao reconhecimento que fazem quanto a sua identificação de raça e classe. Ao verificarmos como as ações das crianças são mediadas pelas práticas educativas escolares, defendemos que em tais espaços sejam constituídas as condições de possibilidade para que elas possam falar – e serem ouvidas – sobre as suas dúvidas e desejos, sobre o que fazem e por que razões o fazem, nas relações entre elas. Enfim, proporcionar emergir suas curiosidades, imaginação e inventividade para, quem sabe, ver irromper algo novo em nosso mundo que prima pelo inacabamento.

  4. A cor da morte: causas de óbito segundo características de raça no Estado de São Paulo, 1999 a 2001 The color of death: causes of death according to race in the State of Sao Paulo, 1999 to 2001

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Batista

    2004-10-01

    Full Text Available OBJETIVO: Sob a premissa de que há diferenças sociais segundo a etnia e que essas diferenças se constituem vulnerabilidade para doença, realizou-se estudo para averiguar se a raça/cor condiciona padrões característicos de óbito. MÉTODOS: Pelos registros de óbitos do Estado de São Paulo dos anos de 1999 a 2001, analisou-se a mortalidade proporcional por causa básica, segundo os capítulos da CID-10, entre as categorias de raça ou cor: branca, preta, parda e outras. A tabela de contingência permitiu, além do teste de chi2, a análise de resíduo, que aponta o excesso de óbitos estatisticamente significante, em cada categoria de causa básica e cor. Usou-se a análise de correspondência para a representação gráfica das relações multidimensionais das distâncias chi2 entre as categorias das variáveis estudadas. RESULTADOS: Foram analisados 647.321 registros válidos, sendo 77,7% de brancos, 5,4% de pretos, 14,3% de pardos e 2,6% de outros. Foi encontrada associação significante entre causas de óbito e raça/cor. Observou-se no mapa multidimensional apresentado que pretos e pardos aparecem distantes, ainda que apresentem um perfil de óbito semelhante, ao contrário de brancos e outros que poderiam ser agrupados numa única categoria. À parte as causas mal definidas que caracterizam apenas os óbitos de pretos, as outras causas de óbito desse grupo são comuns a pretos e pardos, variando, no entanto, em ordem de relação e intensidade. CONCLUSÕES: Foi encontrado na análise da mortalidade segundo a raça/cor, que a morte tem cor. Há uma morte branca que tem como causa as doenças, as quais, embora de diferentes tipos, não são mais que doenças. Há uma morte negra que não tem causa em doenças: são as causas externas, complicações da gravidez e parto, os transtornos mentais e as causas mal definidas.OBJECTIVE: Assuming that ethnicity might be a basis for social differentiation and that such differences might

  5. Determinação da cor, imagem superficial topográfica e ângulo de contato de biofilmes de diferentes fontes de amido Determination of color, topographic superficial image and contact angle of the biofilms of different starch sources

    Directory of Open Access Journals (Sweden)

    Washington Azevêdo da Silva

    2007-02-01

    Full Text Available Atualmente, um dos problemas que acometem o meio ambiente é a poluição ocasionada pelo descarte de filmes plásticos de polímeros sintéticos sem nenhum controle. Uma das alternativas para minimizar este problema é a utilização de amido na elaboração de materiais biodegradáveis que possuem alta degradabilidade quando lançados no meio ambiente. Apesar do número crescente de trabalhos de pesquisas utilizando diferentes materiais biodegradáveis, o conhecimento das propriedades físicas de biofilmes elaborados com amido ainda é bastante reduzido. Objetivou-se com este trabalho determinar a diferença de cor, a imagem superficial topográfica por microscopia eletrônica de varredura e o ângulo de contato de biofilmes elaborados com três diferentes tipos de amido: filme de fécula de batata (FFB, filme de fécula de mandioca (FFM e filme de amido de milho (FAM com três concentrações: 1, 2 e 3% empregando-se um delineamento inteiramente casualizado com três repetições. A interação concentração e tipo de amido foi estatisticamente significativa para ângulo de contato e não significativa para a diferença de cor. A diferença de cor foi afetada pela fonte de amido e o maior valor observado para filme de fécula de mandioca. Com o aumento da concentração de amido, o ângulo de contato diminuiu para filmes de fécula de mandioca e de batata, diferentemente para os biofilmes de milho, onde esta relação foi constante.Nowadays, the pollution has considerably increased by the large amount of the non-degradable synthetic plastics that is discarded everyday in the environment. One of the alternatives that could contribute to minimize this problem would be the use of the starch as main composite in biodegradable films also called biofilms; in other words, this material is easily degradable when disposed in the environment. Despite the growing number of the scientific papers there is a lack of knowledge of the physical properties of

  6. Ultrastructural alterations of choroid plexuses of lateral ventricles of rats (Rattus norvegicus submitted to experimental chronic alcoholism Alterações ultraestruturais dos plexos coróides dos ventrículos laterais de ratos (Rattus norvegicus submetidos a alcoolismo crônico experimental

    Directory of Open Access Journals (Sweden)

    LUÍS FERNANDO TIRAPELLI

    2000-03-01

    Full Text Available Adult male rats (Wistar lineage were alcoholized with sugar cane liquor diluted at 30(0 GL during 300 days and sacrificed every 60 days in 5 stages. Samples of choroid plexuses of lateral ventricles were collected and examined at transmission electronic microscope to detect possible ultrastructural alterations and to raise possible pathological correlations. Gradual changes were observed in these animals during all the experiment: dilatation and enlargement of cisternae of Golgi complex, dilatation of RER, presence of digestive vacuoles and a large amount of pinocytic vesicles as well as vesicles with electronlucent content throughout cytoplasm, as well as an enlargement of intercellular space between basolateral interdigitation of the cells and of the connective tissue. The changes observed in the epithelium and connective tissue of choroid plexuses specially in 240 and 300 days of treatment are presumably due to a disturbance in hydroelectrolitic homeostasis, contributing to several morpho-functional disturbs of central nervous system. No changes were observed in the control group animals.Ratos machos adultos (linhagem Wistar foram alcoolizados com aguardente de cana diluída a 30(0 GL durante 300 dias e sacrificados a cada 60 dias em 5 etapas. Amostras dos plexos coróides dos ventrículos laterais foram coletadas e examinadas ao microscópio eletrônico de transmissão para detectar possíveis alterações ultraestruturais e suas correlações patológicas. Alterações graduais foram observadas nestes animais durante todo o experimento: dilatação e aumento das cisternas de complexo de Golgi, dilatação do retículo endoplasmático rugoso, presença de vacúolos digestivos e grande quantidade de vesículas pinocíticas assim como de vesículas de conteúdo elétron-lúcido por todo o citoplasma, além de aumento do espaço intercelular, entre as interdigitações das células assim como no tecido conjuntivo. As alterações observadas no

  7. Ozonização em meio básico para redução de cor do licor negro de indústria de celulose de algodão Color reduction of black liquor from cotton cellulose industry using ozonation in an alkaline medium

    Directory of Open Access Journals (Sweden)

    José Roberto Guimarães

    2010-03-01

    Full Text Available As indústrias de papel e celulose descartam no ambiente um grande volume de efluente contendo grande quantidade da substância lignina, que atribui coloração e apresenta considerável potencial de toxicidade. Neste trabalho, foi avaliada a ozonização em meio básico para a redução de cor do licor negro gerado por uma indústria de celulose de algodão. Face aos resultados, foi possível observar que, para menores concentrações iniciais de ozônio (0,4 gO3 L-1 h-1, foi necessário um tempo mais longo de ozonização para se obter a redução desejada de 80% da cor. O consumo específico de ozônio, entretanto, em comparação a experimentos com dosagens mais elevadas (4,3 gO3 L-1 h-1 foi menor. Sugere-se que o oxigênio molecular desempenhe, também, um importante papel na oxidação dos compostos, participando do mecanismo de oxidação iniciado por radical hidroxila, •OH, formado na ozonização em meio básico.Pulp and paper mills discharge large amounts of wastewater containing high concentrations of lignin, a coloring substance that is dangerous and presents high toxicity to the environment. In this study, ozonation in alkaline ambience was evaluated for color reduction in black liquor, generated in a cotton linter mill. It was observed that the ozonation time to reach 80% color reduction was higher at a lower initial ozone dose (0,4 gO3 L-1 h-1 in comparison to a higher initial ozone dose (4,3 gO3 L-1 h-1. On the other hand, the amount of consumed oxidant was lower at the lower ozone dose. It is suggested that molecular oxygen participates in the oxidation mechanism of colored compounds, which is initiated by hydroxyl radicals (•OH formed during ozonation in alkaline ambience.

  8. WATER SPRAY-CHILLING OF BEEF CARCASSES AND MEAT AGEING ON WEIGHT LOSS, COLOR AND LONGISSIMUS LUMBORUM ACCEPTANCE ASPERSÃO DE ÁGUA FRIA NO INÍCIO DO RESFRIAMENTO DE CARCAÇAS BOVINAS E MATURAÇÃO DA CARNE SOBRE O PESO, COR E ACEITAÇÃO DO MÚSCULO LONGISSIMUS LUMBORUM

    Directory of Open Access Journals (Sweden)

    PEDRO EDUARDO DE FELÍCIO

    2007-12-01

    Full Text Available

    The objective of this experiment was to evaluate the effects of spray-chilling in carcasses weight loss, purge loss, color and appearance of aged striploin (m. Longissi-mus lumborum steaks. Two lots of intact male, nearly 12 month old, grain finished cattle, were slaughtered, being 16 of the Montana composite breed, in the first slaughter, and 24 crossbreds (½ Nelore X ½ Simental in the second one. After bleeding, electrical stimulation, skinning and evisceration, the carcasses submitted to one of the two cooling systems: (1 Without spray-chilling (SA; (2 With spray-chilling (CA. Carcasses were weighted before and after cooling. In the boning room steaks of 2.5 cm thick from the striploin were taken, vacuum packaged, and aged for 7, 14, 30 and 60 days. Samples were then removed from the package, placed in an expanded polystyrene trays covered with a PVC film, and exposed in refrigerated displays for 48 hours. CIE Lab color was measured after 24 hours using a hand colorimeter. A visual analysis of the samples was also done for the attributes of color, overall acceptability, and buying option. The spray-chilling was efficient in reducing the weight loss (P<0.05. Effects (P<0.001 of the spray-chilling and aging time on purge loss were observed. The samples from the CA carcasses had higher (P<0.001 purge loss, which had an increase at 30 or more days of aging in this treatment but not in the SA. No effect (P>0.05 of the spray-chilling treatment and aging time was observed on the color visual analysis.

    Key-words:  Beef quality purge loss,  spray-chilling, striploin, vacuum package.

    O objetivo desta pesquisa foi avaliar os efeitos da aspersão de água gelada, nas primeiras seis horas de resfriamento, nas perdas de peso por evaporação das carcaças e, também, do tempo de maturação em embalagem a vácuo, nas perdas por exsudação da carne, e na cor e aceita

  9. Effect of light curing tip distance and resin shade on microhardness of a hybrid resin composite Efeito da distância da ponta do aparelho de fotoativação e da cor na microdureza superficial de um compósito híbrido

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Baggio Aguiar

    2005-12-01

    Full Text Available Resin composite shades and resin composite polymerization performed with a distanced light tip are factors that can affect polymerization effectiveness. Thisin vitro study aimed to evaluate the influence of curing tip distance and resin shade on the microhardness of a hybrid resin composite (Z250 - 3M ESPE. Forty-five resin composite specimens were randomly prepared and divided into nine experimental groups (n = 5: three curing tip distances (2 mm, 4 mm, and 8 mm and three resin shades (A1, A3.5, and C2. All samples were polymerized with a continuous output at 550 mW/cm². After 24 hours, Knoop microhardness measurements were obtained on the top and bottom surfaces of the sample, with a load of 25 grams for 10 seconds. Five indentations were performed on each surface of each sample. Results showed that bottom surface samples light-cured at 2 mm and 4 mm presented significantly higher hardness values than samples light-cured at 8 mm. The resin shade A1 presented higher hardness values and was statistically different from C2. The resin shade A3.5 did not present statistical differences from A1 and C2. For the top surface, there were no statistical differences among the curing tip distances. For all experimental conditions, the top surface showed higher hardness values than the bottom surface. It was concluded that light curing tip distance and resin shade are important factors to be considered for obtaining adequate polymerization.A cor do compósito e a polimerização realizada com a ponta do aparelho de fotoativação distante da superfície do compósito são fatores que podem afetar a efetividade de polimerização. Assim, o objetivo deste estudo in vitro foi avaliar a influência desses fatores na microdureza superficial de um compósito híbrido (Z250 - 3M ESPE. Quarenta e cinco espécimes de compósito foram aleatoriamente preparados de acordo com os nove grupos experimentais (n = 5: três distâncias de fotoativação (2 mm, 4 mm e 8 mm e

  10. A implantação do quesito cor/raça nos serviços de DST/Aids no Estado de São Paulo The implementation of the question regarding color/race in STD/AIDS services in the State of São Paulo

    Directory of Open Access Journals (Sweden)

    Márcia Regina Giovanetti

    2007-08-01

    Full Text Available INTRODUÇÃO: O artigo apresenta experiência de implantação e implementação do quesito cor/raça nos serviços de atendimento às DST/Aids no Estado de São Paulo (ESP, através de parceria firmada em 2004 entre a Divisão de Prevenção do Programa Estadual DST/Aids do ESP e o Centro de Estudos das Relações de Trabalho e Desigualdade (CEERT, visando executar um projeto serviços. Trinta e cinco serviços de atendimento às DST/Aids foram envolvidos no projeto e foram realizadas, de 2004 e 2006, sete oficinas de sensibilização e monitoramento do processo de implantação do quesito cor/raça, segundo metodologia de construção participativa e compartilhada do conhecimento, proposta pelo CEERT. Como resultado, verificou-se que o processo de discussão e de reflexão da temática étnico-racial torna a implantação do quesito cor/raça mais fácil. Os folhetos e cartazes propiciam o esclarecimento de profissionais e usuários, facilitando a implantação do quesito. Investir na capacitação dos profissionais da recepção dos usuários é importante para a implantação desse quesito nos serviços de saúde. CONCLUSÃO: A partir desta experiência o Grupo de Trabalho Etnias do Programa Estadual DST/Aids vem ampliando sua atuação. Em 2006, com a parceria das profissionais do Instituto AMA-Psique, iniciou-se o processo para 13 novos municípios, consolidando a implantação do quesito cor/raça no ESP. Esperamos que as informações produzidas possam sensibilizar as diversas esferas, para que sejam propostas e aprovadas políticas públicas que promovam a eqüidade racial na saúde e a qualidade de vida para população negra e indígena.This paper describes the experience to implement a systematic collection of these data on color/race in the STD/Aids care services in the State of São Paulo (SSP, through a partnership signed in 2004 between the Prevention Division of the STD/Aids State Program of the SSP and CEERT (initials in

  11. Estudo pareado da cardiopatia chagásica no Rio Grande do Sul, Brasil: comportamento das alterações eletrocardiográficas em função da cor Matched study of Chagas cardiopaty in southerm Brazil: ECG alterations according to skin color

    Directory of Open Access Journals (Sweden)

    Giovanni Baruffa

    1987-09-01

    Full Text Available O trabalho analisa o comportamento das alterações eletrocardiográficas em 150 indivíduos de cor preta, naturais da área rural do sul do Rio Grande do Sul, pareados com outros tantos brancos do mesmo sexo, idade e procedência. O grupo tinha idade entre 9 e 78 anos, com média de 39,2 e era composto de 57 homens e 93 mulheres. Com referência à sorologia, 84 eram positivos e 66 negativos para a infecção pelo Trypanosoma cruzi. A prevalência de alterações eletrocardiográficas foi significativamente maior entre os pretos, tanto soropositivos quanto soronegativos. As alterações eletrocardiográficas consideradas sugestivas de miocardiopatia chagásica, predominaram significativamente entre os positivos pretos. E mesmo entre os pretos negativos as alterações foram mais numerosas e de maior gravidade com respeito aos negativos brancos. Na opinião dos autores a maior prevalência e severidade das alterações eletrocardiográficas entre os pretos, podem ser atribuídos a vários fatores entre os quais se destacariam: a pobreza e marginalidade das pessoas de cor que implicam trabalhos mais pesados e desgastantes; habitações triatomínica; alimentação mais pobre quantitativa e qualitativamente. Outro fator negativo seriam os valores mais elevados de pressão arterial encontrados entre os pretos que, associados a possíveis influências de ordem racial, podem contribuir e/ou criar condições de patologia miocárdica.The pattern of ECG changes of 150 black individuals from rural areas of southern Rio Grande do Sul, Brazil, was compared with that of a group of 150 whites of similar age, sex and geographical residence. The mean age of the study group was 39.2 years (9-78 years, and 62% were women. 84 out of the 150 showed positive serological reactions to infection by Trypanosoma cruzi. The prevalence of ECG changes was significantly higher among the blacks, irrespective of their serological state. Those changes which were considered as

  12. Spatial distribution of mortality by homicide and social inequalities according to race/skin color in an intra-urban Brazilian space Distribuição espacial da mortalidade por homicídio e desigualdades sociais segundo a raça/cor em um espaço intra-urbano no Brasil

    Directory of Open Access Journals (Sweden)

    Edna Maria de Araújo

    2010-12-01

    Full Text Available INTRODUCTION: In Brazil, deaths by external causes rank first in the mortality statistics. Nevertheless, studies which investigate the relationship between mortality by external causes and race/skin color are scarce. OBJECTIVES: To evaluate the relative contribution of race/skin color to the spatial distribution of mortality by homicide in Salvador, state of Bahia, Brazil, in the period 1998 - 2003. MATERIAL AND METHODS: This is a spatial aggregate study including secondary data on 5,250 subjects, using a unit of analysis called the "weighting area" (WA. Annual average death rates by homicide were estimated. The Global and Local Moran Index were used to evaluate the presence of spatial autocorrelation and the Conditional Auto Regressive (CAR model was employed to evaluate the referred effect, using the R statistical package. RESULTS: Global and Local Moran's I tests were significant. CAR regression showed that the predicted mortality rate increases when there is a growth in the proportion of black males aged between 15 and 49 years. Geometrically weighted regression (GWR showed a very small variation of the local coefficients for all predictors. CONCLUSION: We demonstrated that the interrelation between race, violence and space is a phenomenon which results from a long process of social inequality. Understanding these interactions requires interdisciplinary efforts that contribute to advancement of knowledge that leads to more specific Public Health interventions.INTRODUÇÃO: No Brasil, as mortes por causas externas vêm ocupando as primeiras posições nas estatísticas de mortalidade. No entanto, são escassos os estudos que investigam a relação entre mortalidade por causas externas e raça/cor da pele. OBJETIVOS: Avaliar a contribuição relativa da raça/cor da pele na distribuição espacial da mortalidade por homicídio em Salvador, BA, Brasil no período de 1998 a 2003. MATERIAL E METODOS: Estudo de agregado espacial cuja unidade de an

  13. EVALUACIÓN DEL COLOR DURANTE EL ALMACENAMIENTO DE LA PULPA DE BANANO VERDE IMPREGNADA AL VACÍO CON SOLUCIONES ANTIPARDEANTES AVALIAÇÂO DA COR NO ARMAZENAMENTO DA POLPA DE BANANA VERDE IMPREGNADA A VACUUM USANDO SOLUÇÔES PARA EVITAR O PARDEAMENTO COLOR EVALUATION DURING STORAGE OF GREEN BANANAS PULP IMPREGNATED WITH ANTIBROWNNING SOLUTIONS UNDER VACCUM

    Directory of Open Access Journals (Sweden)

    MISAEL CORTÉS R

    2011-12-01

    Full Text Available La impregnación al vacío es la técnica aplicada por la ingeniería de matrices, como mecanismo de incorporación de soluciones al interior de las matrices alimentarias. Se evaluó la evolución del color en la pulpa de banano verde (PBV (Musa cavendish a diferentes condiciones de almacenamiento: tiempo (0, 3, 6, 9, 12 y 15 días, temperatura (4, 20 y 30°C y empaque, con vacío (CV y sin vacío (SV; bajo tratamientos con sulfitos (500, 1000, 1500 mg/kg PBV y de la interacción antioxidante (60, 90, 120 mg/100 g PBV acidulantes (50, 150, 250 mg/100 g PBV. Los parámetros de color se evaluaron en el espacio CIEL*a*b*, en términos de luminosidad (L* y cromaticidad a* y b*. El ANOVA presentó diferencias estadísticas significativas (p A impregnaçáo a vacuo é é uma técnica usada pela engenharia de matrizes como um meio de incorporar soluçóes na matriz dos alimentos. Neste trabalho foram avaliados a evoluçáo da cor da polpa da banana verde (PBV (Musa cavendish para diferentes condiçóes de armazenamento: tempo (0, 3, 6, 9, 12 e 15 dias, temperatura (4, 20 e 30 °C e condiçóes de embalagem (com vácuo (CV e sem vacuo (SV, sob tratamento com sulfitos (500, 1000, 1500 mg/kg de PBV e interaçáo antioxidante (60, 90, 120 mg/100 g PBV e acidulantes (50, 150, 250 mg/100 g PBV. Os parâmetros de cor foram avaliados no sistema CIÉL*a*b*, em termos de luminosidade (L* e cromaticidade (a*,b*. A análise de variância (ANOVA apresentou diferenças significativas (p Vacuum impregnation is a technique applied by matrix engineering as the mechanism to incorporate the solutions to the interior of an alimentary matrix. The development of the color of the pulp of unripe Banana (PUB (Musa cavendish was evaluated in different storage conditions: Time 0, 3, 6, 9, 12, and 15 days, Temperature 4, 20, and 30°C, packed with vacuum (WV and without vacuum (NV under sulfite treatment (500, 1000, 1500 mg/kg PUB and the antioxidant interaction (60, 90, 120 mg

  14. Diferenciais de raça/cor da pele em anos potenciais de vida perdidos por causas externas Diferenciales de raza/color de la piel en años potenciales de vida perdidos por causas externas Race/skin color differentials in potential years of life lost due to external causes

    Directory of Open Access Journals (Sweden)

    Edna Maria de Araújo

    2009-06-01

    Full Text Available OBJETIVO: As mortes por causas externas representam um dos mais importantes desafios para a saúde pública, sendo a segunda causa de óbito no Brasil. O objetivo do estudo foi analisar os diferenciais de mortalidade por causas externas segundo raça/cor da pele. MÉTODOS:Estudo descritivo realizado em Salvador (BA, com 9.626 registros de óbitos por causas externas entre 1998 e 2003. Dados foram obtidos do Instituto Médico Legal e Instituto Brasileiro de Geografia e Estatística. O indicador "anos potenciais de vida perdidos" foi utilizado para identificar diferenciais entre grupos etários, de raça/cor da pele e sexo. RESULTADOS: As mortes por causas externas determinaram perda de 339.220 anos potenciais de vida, dos quais 210.000 foram devidos aos homicídios. Indivíduos negros morreram em idades mais precoces e perderam 12,2 vezes mais anos potenciais de vida devido a mortes por homicídio que indivíduos brancos. Embora a população negra (pardos e pretos fosse três vezes maior que a população branca, o número de anos perdidos daquela foi 30 vezes superior. A população de pretos era 11,4% menor que a população branca, mas apresentou anos perdidos quase três vezes mais. Mesmo após a padronização por idade, mantiveram-se as diferenças observadas no indicador de anos potenciais perdidos/100.000 hab e nas razões entre estratos segundo raça/cor. CONCLUSÕES: Os resultados mostram diferenciais na mortalidade por causas externas segundo raça/cor da pele em Salvador. Os negros tiveram maior perda de anos potenciais de vida, maior número médio de anos não vividos e morreram, em média, em idades mais precoces por homicídios, acidentes de trânsito e demais causas externas.OBJETIVO: Las muertes por causas externas representan uno de los más importantes desafíos para la salud pública, siendo la segunda causa de óbito en Brasil. El objetivo del estudio fue analizar los diferenciales de mortalidad por causas externas seg

  15. Diagnóstico não Invasivo de Hipertensão Pulmonar e Cor Pulmonale nos Doentes com Doença Pulmonar Crónica Obstrutiva – Importância da Ecocardiografia++ Trabalho concorrente ao Prémio Thomé Villar 1993 (Secção B, da SPPR.

    Directory of Open Access Journals (Sweden)

    Pilar Azevedo

    1995-01-01

    Full Text Available RESUMO: A presença de Hipertensão Pulmonar e de Cor Pulmonale é um factor de mau prognóstico no contexto da Doença Pulmonar Crónica Obstrutiva.A Ecocardiografia modo M. bidimensional e Doppler é um método não invasivo que permite avaliar as alterações morfológicas e funcionais do coração direito e estimar a Pressão Sistólica na Artéria Pulmonar.No entanto, condicionantes vários como a hiperinsuflação pulmonar, as alterações da parede torácica e a obesidade frequentemente presentes em doentes com patologia respiratória crónica, podem impedir a obtenção de exame com boa qualidade téscnica.O objectivo deste trabalbo é avaliar a exeqwoilidade deste método nos doentes com Doença Pulmonar Crónica Obstrutiva e correlacionar os dados obtidos por Ecocardiografia com os aspectos clinicos sugestivos de falência cardíaca direita.Foram estudados 35 doentes, 29 do sexo masculino e 6 do sexo feminino, com idade média de 66,2 anos, com Doença Pulmonar Crónica Obstrutiva seguidos na Consults de Oxigenioterapia de Longa Duração do Serviço de Pneumologia do Hospital de Santa Maria.Cada doente realizou um Ecocardiograma modo M, bidimensional e Doppler para determinação da espessura da parede livre do ventrículo direito (VD, do diâmetro da cavidade ventricular direita e da Pressão Sistólica na Artéria Pulmonar (PAPs utilizando as vias paraesternal esquerda, apical e subcostal.Em 80% dos doentes estudados obtiveram-se registos satisfatórios que permitiram determinar a espessura da parede livre do VD, avaliar o diâmetro desta cavidade e estimar a PAPs.Foram registados critérios de Hipertrofia Ventricular Direita em 75% dos registos validados (espessura média da parede livre do VD - 7,1±1,3 mm e critérios de dilatação ventricular direita em 25% dos casos.Em 60% destes doentes conseguiu-se estimar a PAPs

  16. Consumo alimentar na gestação e no pós-parto segundo cor da pele no município do Rio de Janeiro Food intake during pregnancy and postpartum according to skin color in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Elisa Maria de Aquino Lacerda

    2007-12-01

    Full Text Available OBJETIVO: Avaliar o consumo alimentar durante a gestação e pós-parto, segundo cor da pele. MÉTODOS: Estudo longitudinal prospectivo que incluiu 467 mulheres entre 15 e 45 anos no período pós-parto, no município do Rio de Janeiro, entre 1999 e 2001. Foi aplicado um questionário de freqüência de consumo de alimentos aos 15 dias pós-parto (consumo referente ao período da gestação e aos seis meses (consumo referente ao período pós-parto. Foi utilizada análise de covariância para analisar diferenças no consumo alimentar, segundo cor da pele, controlada pela escolaridade. RESULTADOS: Durante a gestação, pretas e pardas apresentaram consumo de energia 13,4% e 9,1% (p=0,009 e p=0,028 e consumo de carboidrato 15,1% e 10,5% maior que brancas (p=0,005 e p=0,014, respectivamente. Mulheres pretas e brancas apresentaram consumo energético 34% e 20% acima das recomendações nutricionais, respectivamente (p=0,035. Durante o período pós-parto, as pretas apresentaram consumo de energia 7,7% maior e consumo de lipídios 14,8% maior que as brancas; consumo de ácidos graxos saturados 23,8% maior que brancas (p=0,003 e 13% maior que pardas (p=0,046. A adequação de consumo de lipídios e ácidos graxos saturados foi maior em pretas que em brancas (p=0,024 e p=0,011, respectivamente. CONCLUSÕES: Os resultados mostram ser necessário revisar estratégias de intervenção nutricional no pré-natal e implementar assistência nutricional no pós-parto, para ajustar o consumo alimentar a níveis adequados, considerando as diferenças por cor/raça identificadas.OBJECTIVE: To assess dietary intake during pregnancy and postpartum according to skin color. METHODS: A longitudinal prospective study was carried out comprising 467 postpartum women aged between 15-45 years in the city of Rio de Janeiro, Southeastern Brazil, in 1999-2001. A food frequency questionnaire was administered at two weeks postpartum (intake covering the pregnancy period and at

  17. Incidental discovery of an unusual right atrial membrane in an adult patient

    Directory of Open Access Journals (Sweden)

    Nasrin N Aldawoodi

    2012-01-01

    Full Text Available We describe presence of an unusual right atrial membrane in a 30-year old female with end stage renal disease, hypertension and peripheral vascular disease. The patient was scheduled for midline sternotomy and pericardiotomy and removal of a migrated vascular stent in the right pulmonary artery. An intraoperative transesophageal echocardiogram (TEE revealed an unusual membranous structure with fenestrations that stretched across the right atrium with attachments superiorly at the free wall and inferiorly at the inter-atrial septum. There was no evidence of flow obstruction across the tricuspid valve. Some of the considerations for the likely diagnosis of this structure were a prominent Eustachian valve, persistent Chiari network, aneurysmal inter-atrial septum, an inter-atrial septal cyst or Cor triatriatum dexter (CTD.

  18. Isolated persistent left-sided superior vena cava, giant coronary sinus, atrial tachycardia and heart failure in a child

    Directory of Open Access Journals (Sweden)

    Nagaraja Moorthy

    2013-09-01

    Full Text Available Persistence of a left-sided superior vena cava (PLSVC with absent right superior vena cava (isolated PLSVC is a very rare venous malformation and commonly associated with congenital heart disease or alterations of the cardiac situs. We describe an unusual case of a young boy presenting with persistent atrial tachycardia and congestive heart failure. He was detected to have unexplained grossly dilated right atrium, right ventricle with systolic dysfunction and a giant coronary sinus (CS. The dilated CS closely mimicked a pseudo cor-triatriatum on echocardiography. Contrast echocardiography from both arms revealed opacification of the CS before the right atrium. Bilateral upper limb venography confirmed the presence of absent right SVC and isolated persistent left SVC draining into the giant coronary sinus.

  19. Influência da cor de pele auto-referida na prevalência da síndrome metabólica numa população urbana do Brasil Influencia del color de la piel autodeclarado en la prevalencia del síndrome metabólico en una población urbana de Brasil Influence of the self-reported skin color on the prevalence of metabolic syndrome in an urban Brazilian population

    Directory of Open Access Journals (Sweden)

    Paulo José Bastos Barbosa

    2010-01-01

    Full Text Available FUNDAMENTO: A síndrome metabólica tem uma elevada prevalência em diferentes partes do mundo, com variações entre diferentes grupos étnicos. OBJETIVO: Este estudo pretende explorar a influência da cor de pele auto-referida sobre a prevalência da SM. MÉTODOS: Estudo transversal, realizado em subgrupo populacional em Salvador, Brasil. Utilizou-se auto-definição de cor de pele (branca, parda e negra e o critério de SM do ATP-III. Foi usado o quiquadrado para tendência a fim de analisar gradiente das prevalências entre os grupos e a regressão logística para análises de associações. RESULTADOS: A prevalência geral da SM, ajustada por variáveis potencialmente confundidoras, não diferiu entre brancos (23,3%, pardos (23,3% e negros (23,4%,. A análise por sexo mostrou entre os homens redução da prevalência da SM dos brancos, 26,2% IC95%(20,7-31,7, em comparação aos negros, 17,5% IC95% (12,3-22,8, e uma prevalência intermediária entre os pardos, 21,9% IC95% (18,6 - 25,1, p tend= 0,002. Entre as mulheres, a tendência foi inversa, maior nas negras, 27,0% IC95% (22,2-31,8, e menor nas brancas, 20,5% IC95%(15,6-25,4, p tend= 0,02. Na análise multivariada da associação entre cor de pele e SM (branco=grupo de referência, a cor negra entre os homens foi fator de proteção, razão de prevalência (RP= 0,60 (0,36 - 0,97, enquanto que nas mulheres tendeu a ser fator de risco, RP= 1,33 (0,94 - 1,78. CONCLUSÃO: A prevalência da SM variou em função da cor de pele de modo inverso entre homens e mulheres. Ser negro foi fator de proteção entre homens e de risco nas mulheres.FUNDAMENTO: El síndrome metabólico tiene una elevada prevalencia en diferentes partes del mundo, con variaciones entre diferentes grupos étnicos. OBJETIVO: Este estudio pretende explorar la influencia del color de la piel autodeclarado sobre la prevalencia del SM. MÉTODOS: ESTUDio transversal, realizado en subgrupo poblacional en Salvador, Brasil. Se utiliz

  20. Cor, iluminação e orientação do reverso de uma máscara facial não afetam a ilusão da máscara côncava Color, illumination and orientation of a hollow mask do not affect the hollow-face illusion

    Directory of Open Access Journals (Sweden)

    Maria Amélia Cesari Quaglia

    2009-08-01

    Full Text Available Em condição monocular, 40 observadores julgaram o reverso côncavo de uma máscara facial monocromada cinza e de outra policromada (iluminados por cima, por baixo, pela direita e pela esquerda na posição vertical e na posição vertical invertida, iluminado por baixo como côncavos, planos ou convexos. Além disso, as magnitudes dos seus relevos percebidos foram reproduzidas ao se esticar uma trena retrátil. Independente da cor, iluminação e orientação das máscaras, a maioria das respostas indicou que os reversos das máscaras foram percebidos como convexos. E mesmo nas poucas respostas em que as máscaras foram classificadas como planas, houve atribuição de relevo mensurável. Estes resultados confirmam que a ilusória profundidade da máscara facial côncava como convexa é robusta sob influência de variáveis diversas, o que sugere atuação predominante de processos de alta ordem sobre os processos de baixa ordem na percepção visual de faces.With monocular viewing, forty observers judged a monochrome-gray and a polychrome hollow face mask (illuminated from above, from below, from the right and from the left, and upside-down illuminated form below as inward deep, flat or outward deep. They were also asked to reproduce the perceived depth of the mask by pulling out a tape measure. Regardless of color, illuminating condition and mask orientation, most of the responses indicated that the hollow faces were perceived as outward deep. Even in the few occasions in which the masks were reported flat, measurable depths were assigned on the tape measure. These results support that the hollow face illusion is robust even under diverse variable effects, which suggest preponderant top-down over bottom-up processes on visual face perception.

  1. The effect of irradiation and thermal process on beef heme iron concentration and color properties Efeito da irradiação e processo térmico na concentração do ferro heme e nas propriedades de cor da carne

    Directory of Open Access Journals (Sweden)

    Liliana Perazzini Furtado Mistura

    2009-03-01

    Full Text Available The aim of this study was to evaluate the influence of irradiation and thermal process on the heme iron (heme-Fe concentration and color properties of Brazilian cattle beef. Beef samples (patties and steaks were irradiated at 0-10 kGy and cooked in a combination oven at 250 ºC for 9 minutes with 70% humidity. Total iron and heme iron (heme-Fe concentrations were determined. The data were compared by multiple comparisons and fixed- effects ANOVA. Irradiation at doses higher than 5 kGy significantly altered the heme-Fe concentration. However, the sample preparation conditions interfered more in the heme-Fe content than did the irradiation. Depending on the animal species, meat heme iron levels between 35 and 52% of the total iron are used for dietetic calculations. In this study the percentage of heme-iron was, on average, 70% of the total iron showing that humidity is an important factor for its preservation. The samples were analyzed instrumentally for CIE L*, a*, and b* values.O objetivo deste estudo foi avaliar a influência da irradiação e de processos térmicos na concentração do ferro heme (Fe heme e nas propriedades de cor da carne do gado brasileiro. As amostras da carne (hambúrgueres e bifes foram irradiadas com 0-10 kGy e foram cozidas em um forno combinado a 250 ºC por 9 minutes com umidade de 70%. As concentrações de ferro total e de ferro heme foram determinadas. Os dados foram comparados por comparações múltiplas e por efeitos fixos, ANOVA. Irradiação em doses mais altas do que 5 kGy alteraram significativamente a concentração de Fe heme. Entretanto, as condições de preparo da amostra, interferiram muito mais na quantidade de Fe heme do que a irradiação. Dependendo da espécie animal, os níveis do ferro heme da carne estão entre 35 e 52% do ferro total e são usados para cálculos dietéticos. Em nosso estudo, a porcentagem de ferro heme foi em média, 70% do ferro total, mostrando que a umidade é um fator

  2. Impacto dos mediadores redox na remoção de cor de corantes azo e antraquinônico por lodo granular anaeróbio sob condições mesofílicas e termofílicas Impact of redox mediators on colour removal of azo and anthraquinone dyes by anaerobic granular sludge under mesophilic and thermophilic conditions

    Directory of Open Access Journals (Sweden)

    André Bezerra dos Santos

    2007-03-01

    Full Text Available Investigou-se o efeito de diferentes mediadores redox (MR na remoção de cor de corantes azo e antraquinônico pelo uso de lodo granular anaeróbio sob condições mesofílicas (30ºC e termofílicas (55ºC. Comprovou-se em experimento em batelada que a adição de concentrações catalíticas de MR pode ter um efeito marcante nas taxas de descoloração do corante azo Reactive Red 2 (RR2, mas o mesmo comportamento não pode ser obtido com o corante antraquinônico Reactive Blue 5 (RB5. Entretanto, com ambos os corantes, o simples aumento da temperatura de incubação para condições termofílicas fez acelerar consideravelmente os processos de descoloração, comparados com condições mesofílicas. Por exemplo, a constante de primeira ordem "k" da redução dos corantes RR2 e RB5, foi aumentada em 6,2 e 11 vezes, respectivamente, à 55ºC quando comparado com 30ºC. Por fim, comprovou-se em experimentos de fluxo contínuo, a boa performance do tratamento termofílico na descoloração redutiva de corantes azo.The effect of different redox mediators (RM on colour removal of azo and anthraquinone dyes was investigated with anaerobic granular sludge under mesophilic (30ºC and thermophilic (55ºC conditions. Batch experiments revealed that an addition of catalytic concentrations of RM provided a remarkable effect on the decolourisation rates of the azo dye Reactive Red 2 (RR2, but the same effect could not be obtained with the anthraquinone dye Reactive Blue 5 (RB5. Nevertheless, for both dyes, the temperature increase to thermophilic conditions was an effective strategy to considerably accelerate the decolourisation process compared to mesophilic conditions. For instance, the first-order rate constant "k" of RR2 and RB5 reduction, was increased in 6.2 and 11-fold, respectively, at 55ºC in comparison with 30ºC. Such an effect of the temperature on the reductive decolourisation of azo dye was also verified in continuous flow experiments.

  3. Causes and clinical characteristics of chronic cor-pulmonale in ...

    African Journals Online (AJOL)

    Results: Bronchial asthma (36%), chronic fibrocavitary tuberculosis (31%) and chronic bronchitis/emphysema (33%) were the most frequent underlying causes and occurred either singly or in combination in 36(86%) of patients. Interstitial lung disease occurred in five (11.9%) patients. Right-sided heart failure and cyanosis ...

  4. Sustitución de lardo por grasa vegetal en salchichas: incorporación de pasta de aguacate. Efecto de la inhibición del oscurecimiento enzimático sobre el color Substituição do toucinho por gordura vegetal em salsichas: adição da pasta de abacate. Efeito da inibição do escurecimiento enzimatico na cor

    Directory of Open Access Journals (Sweden)

    Ubaldo Rueda-Lugo

    2006-06-01

    Full Text Available La sustitución de grasa animal es importante para mejorar la calidad nutricional de los alimentos de origen animal. Tradicionalmente, los embutidos contienen cantidades relativamente altas de grasas insaturadas, por lo que se ha buscado la sustitución parcial o total de estas con grasas o aceites de origen vegetal. El aprovechamiento del aguacate como fuente de grasa vegetal es una alternativa para este tipo de productos. La oxidación de este fruto es uno de los principales problemas durante la industrialización. En este trabajo se han añadido dos inhibidores del oscurecimiento enzimático, ácido ascórbico y eritorbato de sodio, para determinar el efecto de éstos sobre el color de salchichas de cerdo. Se han encontrado diferencias en la luminosidad de las muestras con respecto al tratamiento control, además de que este mismo parámetro se ha reducido con el tiempo de almacenamiento. No ha habido efecto significativo de los antioxidantes sobre las otras componentes del color. El uso de eritorbato de sodio en la elaboración de pasta de aguacate ha reducido el oscurecimiento de la pasta durante su congelación, sin afectar mayormente otros parámetros de color del producto terminado. La aceptación del producto por un grupo de consumidores ha sido aceptable.A substituição da gordura animal ou toucinho é importante para melhorar a qualidade nutricional dos alimentos de origem animal. Tradicionalmente, os embutidos contêm quantidades relativamente elevadas de gorduras insaturadas, e a substituição parcial ou total com gordura vegetal ou óleo é desejável. O abacate é fonte de gordura vegetal como uma alternativa para este tipo de produto. A oxidação desta fruta é um dos problemas principais durante a industrialização. Neste trabalho foram adicionados dois inibidores de escurecimento enzimatico, ácido ascórbico e eritorbato do sódio, para determinar o efeito destes na cor das salsichas. As diferenças na luminosidade das

  5. Bens de consumo e insegurança alimentar: diferenças de gênero, cor de pele autorreferida e condição socioeconômica Household appliances and food insecurity: gender, referred skin color and socioeconomic differences

    Directory of Open Access Journals (Sweden)

    Leticia Marin-Leon

    2011-09-01

    Full Text Available OBJETIVO: Com base nos dados da Pesquisa Nacional por Amostra de Domicílios (PNAD, 2004, foram comparadas as diferenças na prevalência de insegurança moderada/grave em relação à segurança alimentar, e insegurança leve quanto à posse de bens de consumo e outras condições socioeconômicas e demográficas. MÉTODOS: Foram estudados os domicílios particulares permanentes, com rendimento domiciliar per capita de até um salário mínimo, utilizando-se a Escala Brasileira de Insegurança Alimentar respondida por morador do domicílio (n=51.357. A associação entre as variáveis e a variável dependente (segurança alimentar foi verificada pelo teste do Χ2 com nível de significância de 5%. Foram calculadas razões de prevalência brutas e intervalos de confiança de 95% e a análise ajustada foi conduzida por meio de regressão múltipla de Poisson, utilizando Stata 8.0, que incorpora as ponderações do desenho amostral com delineamento complexo. RESULTADOS: A renda domiciliar mensal per capita foi a variável com maior força de associação com a segurança alimentar. Tanto em áreas urbanas quanto rurais, foram encontradas elevadas razões de prevalência para insegurança alimentar moderada ou grave nos domicílios chefiados por mulheres, de cor negra, presença no domicílio de seis ou mais moradores, localização metropolitana e com ausência de alguns bens específicos (fogão, filtro, geladeira, freezer, máquina de lavar roupa e telefone celular. Em modelo que incluiu, entre os bens, apenas a posse de geladeira, a maior razão de prevalência ocorreu na renda de até ¼ de salário mínimo, seguindo-se a ausência de posse de geladeira, tanto nos domicílios chefiados por homens brancos, como por negros e mulheres brancas ou negras. Embora os domicílios chefiados por mulheres e por negros apresentem maior insegurança alimentar, as diferenças intragrupais foram maiores em domicílios chefiados por homens brancos e menores

  6. Raça, cor e etnia em estudos epidemiológicos sobre populações brasileiras: revisão sistemática na base PubMed Race, color and ethnicity in epidemiologic studies carried out with Brazilian populations: systematic review on the PubMed database

    Directory of Open Access Journals (Sweden)

    Juliana Fernandes Kabad

    2012-01-01

    Full Text Available O objetivo foi analisar o uso das variáveis raça, cor e etnia em estudos epidemiológicos sobre populações brasileiras. Trata-se de revisão sistemática, conduzida na base PubMed,entre janeiro de 2000 e julho de 2010. Para o conjunto dos trabalhos revisados, aplicou-se ficha com questões sobre seus objetivos e a relevância da classificação étnico-racial em suas análises, características sócio-demográficas e aspectos da identificação étnico-racial das populações investigadas, bem como o seguimento de recomendações quanto ao uso das classificações de raça, cor e etnia. Dos 1.174 artigos identificados, 151 foram elegíveis para a revisão. Maiores proporções de cada um dos seguintes aspectos foram observadas nos artigos em que a identificação étnico-racial ocupou papel central em suas análises - destes, 18% justificaram o emprego das categorias; 16% consideraram a classificação étnico-racial como fluida e relativa ao contexto da produção dos dados; 65% descreveram o método da classificação étnico-racial; 17% entenderam esta classificação como medida de variabilidade genética; 26% interpretaram a variável como fator de risco para o desfecho em questão; 47% consideraram fatores socioeconômicos na interpretação das desigualdades étnico-raciais; e 27% incluíram tais fatores no ajuste de modelos estatísticos. Apenas dois estudos explicitaram o conceito, que embasou o uso da variável étnico-racial. Uma proporção expressiva dos estudos epidemiológicos analisados não segue os critérios mínimos que vêm sendo sugeridos quanto ao uso de variáveis relacionadas à classificação étnico-racial, de modo que este aspecto deve ser aperfeiçoado nas pesquisas em Saúde Coletiva.This paper aims to analyze the use of the variables race, color and ethnicity in epidemiologic studies, carried out with Brazilian populations. This is a systematic review, conducted in the PubMed bibliographic database, on papers

  7. Na ante-sala da discriminação: o preço dos atributos de sexo e cor no Brasil (1989-1999 On the threshold of discrimination: the burden of sex and race attributes in Brazil (1989-1999

    Directory of Open Access Journals (Sweden)

    Ciro Biderman

    2004-08-01

    Full Text Available O Brasil se caracteriza por elevados patamares de desigualdades nos rendimentos entre negros e brancos, homens e mulheres. Para analisar com medidas robustas o nível de discriminação prevalecente no mercado de trabalho procuramos, neste texto, controlar os efeitos de atributos individuais (como escolaridade e idade e de características dos espaços de trabalho (como formalização da relação de trabalho, região geográfica e posição na hierarquia de ocupações. A partir da comparação entre duas bases de microdados da PNAD - Pesquisa Nacional por Amostra de Domicílios, relativas aos anos de 1989 e 1999, foi possível avançar três ordens de resultados. Em primeiro lugar, que a discriminação no mercado, no que concerne às mulheres, é ainda mais elevada que aquela medida pelo simples hiato entre os seus rendimentos e aqueles auferidos pelos homens; já com respeito aos trabalhadores/as negros/as, o efeito líquido que poderia ser atribuído à discriminação salarial parece menos elevado, na medida em que outros fatores, por vezes ainda mais importantes, atuam simultaneamente, explicando as significativas diferenças salariais que os separam dos/das trabalhadores/as brancos/as. Em segundo lugar, observamos que a década de 1990 reduz a intensidade com que fatores ligados à discriminação de sexo e cor atuavam sobre tais desigualdades; entretanto, tal redução é ainda de pequena monta e se sustenta nas perdas importantes ocorridas no salário médio dos homens, notadamente brancos. Em terceiro lugar, quando observados ao longo das distintas posições na distribuição de renda, os determinantes da desigualdade variam em sua importância, e os fatores ligados à discriminação de sexo e cor mostram-se os mais decisivos, em especial entre as mulheres e negros que chegam a galgar posições no topo da hierarquia social.Brazil is characterized by high levels of income inequality between blacks and whites, men and women. To

  8. O diagnóstico do carcinoma metastático de coróide pela biópsia aspirativa com agulha fina (BAAF: relato de caso The diagnosis of metastatic carcinoma of the choroid using fine-needle aspiration biopsy (FNAB: case report

    Directory of Open Access Journals (Sweden)

    Zélia Maria da Silva Corrêa

    2003-01-01

    Full Text Available OBJETIVO: Relatar o caso de um paciente com carcinoma de pulmão cuja primeira metástase detectada foi em coróide e a abordagem diagnóstica deste caso. MÉTODOS: Um homem de 35 anos, em tratamento devido a uma condensação pulmonar isolada, referiu baixa da acuidade visual súbita, dor, secreção e olho vermelho (olho direito há 10 dias. Ao exame oftalmológico foi detectada a presença de descolamento não regmatogênico de retina e múltiplos focos tumorais em coróide confirmado pela ultra-sonografia ocular diagnóstica. Foi sugerida biópsia aspirativa com agulha fina (BAAF para diagnosticar possível doença metastática. A biópsia aspirativa com agulha fina foi realizada sob anestesia peribulbar e sedação. A rota escolhida foi transvítrea através de esclerotomia a 4 mm do limbo. O procedimento foi monitorado via oftalmoscopia binocular indireta. Foram obtidas 2 amostras de focos tumorais diferentes. Após a biópsia aspirativa com agulha fina, as amostras foram encaminhadas para processamento, fixação e coloração pelos métodos Papanicolaou e hematoxilina-eosina. RESULTADOS: A citologia confirmou a suspeita de múltiplos focos metastáticos coroídeos. Os aspirados ocular e pulmonar revelaram ser de mesma origem devido à reação positiva com pan-citoqueratina (AE1/AE3. O paciente evoluiu para óbito 4 meses após diagnóstico citológico de carcinoma metastático ocular. CONCLUSÕES: A biópsia aspirativa com agulha fina foi eficiente em diagnosticar e correlacionar a citologia ocular com o tumor primário por métodos citoquímicos neste caso. A biópsia aspirativa com agulha fina ainda deve ser usada em casos selecionados e pesquisas futuras serão necessárias para que este procedimento diagnóstico seja considerado padrão em oftalmologia.PURPOSE: To report a case of a patient with lung carcinoma in which the first detected metastasis was to the choroid, how it was diagnosed and confirmed. METHODS: A 35 year-old white

  9. The Effect of Marginal Seal of Veneering DiCor (trade name) Substrates with DiCor Plus Porcelain

    Science.gov (United States)

    1991-05-01

    has resorted to a variety of materials in pursuit of this goal. Over the years, wood, wire, metal, acrylic resin, porcelain, metal-resin restorations...the French apothecary, Alexis Duchateau’s first set of all mineral denture teeth constructed in 1774. These teeth were relatively white and opaque. It...gold soldered them to a platinum denture base. Most dental ceramic work at that time was associated with complete denture construction. Then, in 1817

  10. Effect of the extract of persimmon (Diospyros kaki L. cv. ‘Rama Forte’and rosemary oily extract (Rosmarinus officinalis L. on the sensory characteristics and color stability of frozen beef burgersEfeito de extratos de caqui (Diospyros kaki L. cultivar Rama Forte e do extrato oleoso de alecrim (Rosmarinus officinalis L. nas características sensoriais e na estabilidade da cor de hambúrguer de carne bovina congelado

    Directory of Open Access Journals (Sweden)

    Leadir Lucy Martins Fries

    2012-06-01

    da cor de hambúrguer de carne bovina congelado. Para tanto foi elaborado o extrato hidroetanólico bruto que foi fracionado obtendo-se a fração hexânica, clorofórmica, de acetato de etila e a fração residual. Para o preparo das amostras de hambúrguer foi elaborada uma formulação básica que foi dividida em partes: controle, padrão (formulação adicionada de 0,1% de eritorbato de sódio, tratamento 1 (0,5% de extrato hidroetanólico bruto, tratamento 2 (0,7% de extrato hidroetanólico bruto, tratamento 3 (0,5% da fração residual, tratamento 4 (0,7% da fração residual, tratamento 5 (0,5% da fração acetato de etila, tratamento 6 (0,7% da fração acetato de etila e tratamento 7 (0,10% de extrato oleoso de alecrim. As amostras de hambúrguer foram armazenadas a –25 ºC por 14 meses e submetidas a análise sensorial (cor, aroma, sabor e textura no início do experimento e a determinação da cor (L*, a*, b* e h* a cada 2 meses. A adição dos extratos não promoveu alteração dos atributos sensoriais do hambúrguer bovino no tempo zero de armazenamento. Ocorreu tendência de diminuição dos valores de a* e aumento dos valores de h* das amostras de hambúrguer congeladas ao longo do período de armazenamento. As amostras adicionadas da fração acetato de etila (0,5 e 0,7% e do extrato oleoso de alecrim apresentaram maiores valores de a* que as demais amostras ao longo do período de armazenamento e menores valores de h* que a amostra padrão, no final do período avaliado, indicando que a adição da fração acetato de etila e do extrato de alecrim contribuiram na retenção e estabilidade da cor vermelha das amostras de hambúrguer de carne bovina durante o período de armazenamento do produto congelado.

  11. Determinantes da retenção de peso pós-parto segundo a cor da pele em mulheres do Rio de Janeiro, Brasil Determinants of postpartum weight retention according to skin color among women in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Ivyna Spinola Caetano Jordão

    2005-12-01

    Full Text Available OBJETIVO: Investigar os fatores associados à retenção de peso pós-parto segundo a cor da pele. MÉTODOS: Foi conduzido um estudo de coorte com quatro ondas de seguimento: aos 15 dias e 2, 6 e 9 meses pós-parto. As 450 participantes do estudo (idade entre 15 e 45 anos foram recrutadas em uma maternidade e em um centro municipal de saúde localizados no Município do Rio de Janeiro, Brasil. A retenção de peso pós-parto foi definida como variável dependente. As co-variáveis investigadas foram idade da mãe, estado marital, habilidade para ler uma carta, hábito de fumar, renda familiar mensal em reais, número de filhos, idade ao primeiro parto e escore de atividade física no trabalho e no lazer. Os dados foram analisados em modelos de regressão linear longitudinal multivariados com efeitos mistos. RESULTADOS: Os fatores que permaneceram associados à retenção de peso pós-parto foram: para as mulheres brancas, tempo pós-parto (beta = -0,0061, valor P = 0,0002, estado marital (casada/ solteira beta = -0,9279, valor P = 0,0457 e idade ao primeiro parto (beta = -0,1553, valor P = 0,0364; para as pardas, tempo pós-parto (beta = -0,0062, valor P OBJECTIVE: To investigate factors associated with postpartum weight retention according to skin color in the city of Rio de Janeiro, Brazil, as part of the effort to help control overweight and obesity. METHODS: We carried out a cohort study with data collection at four points after delivery: 15 days, 2 months, 6 months, and 9 months. The 450 participants (15 to 45 years of age were recruited from a maternity center and a city health center in Rio de Janeiro. Postpartum weight retention was defined as the dependent variable. The following covariates were investigated: maternal age, marital status, ability to read a letter, smoking, monthly family income, number of children, age at first delivery, a score for physical activity at work, and a score for physical activity during leisure time. The

  12. Cor/raça no Estudo Pró-Saúde: resultados comparativos de dois métodos de autoclassificação no Rio de Janeiro, Brasil Ethnicity/race in the Pró-Saúde Study: comparative results of two methods of self-classification in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Marcos Chor Maio

    2005-02-01

    Full Text Available Variações nos sistemas de classificação da cor/raça e a dependência contextual de sua aplicação são alguns dos desafios para a realização de estudos de saúde com recorte étnico/racial no Brasil. As respostas a duas abordagens distintas para autoclassificação de raça - questão fechada (IBGE e questão aberta - foram comparadas em um estudo de coorte dos funcionários de uma universidade no Rio de Janeiro. De acordo com a pergunta fechada, 54,0% dos 3.717 participantes classificaram-se como brancos, 30,0% como pardos e 16,0% como pretos. Segundo a pergunta aberta, essas proporções foram 53,0%, 25,0% e 22,0%, respectivamente, agrupando-se os termos moreno, mestiço e mulato na categoria parda. Apesar da concordância elevada (kappa = 0,80; IC95%: 0,78-0,82, proporções não desprezíveis de participantes negros ou pardos (pergunta aberta escolheram categorias mais "claras" entre as opções do IBGE. A utilização do recorte étnico/racial nos estudos de saúde pode não apenas revelar dados sobre as desigualdades sociais no Brasil, mas também contribuir para a formulação de políticas na área da saúde pública informadas pelas especificidades da sociedade brasileira.Variations in classification systems related to color/race and the contextual dependence of their utilization are two challenges for researchers conducting health studies within an ethnic/racial framework. A comparison was made between the results obtained by two distinct approaches to racial self-classification - a closed question (using categories from the IBGE, or National Census Bureau and an open-ended question - in a cohort study of employees at a university in Rio de Janeiro. According to the closed question, 54.0% of the 3,717 respondents classified themselves as white, 30.0% as brown (or mixed-race, and 16.0% as black. According to answers to the open-ended question, the proportions were 53.0%, 25.0%, and 22.0%, respectively, when the terms "moreno

  13. Adaptabilidade e estabilidade fenotípica em genótipos de feijão de cor (Phaseolus vulgaris L. em três ambientes distintos Adaptability and fenotypic stability of collor bean genotypes (Phaseolus vulgaris L. in three different environments

    Directory of Open Access Journals (Sweden)

    Jefferson Luís Meirelles Coimbra

    1999-09-01

    Full Text Available No biênio 1996/97 foram testados, em três ambientes, vinte e um genótipos de feijão de cor, com o objetivo de identificar e avaliar os parâmetros de adaptabilidade e estabilidade fenotípica para a produtividade de grãos. Foi utilizado o delineamento experimental, blocos casualizados, com três repetições por tratamento. Os genótipos revelaram diferenças altamente significativas entre si, em todos os ambientes avaliados. Na análise de variância conjunta, os efeitos das causas de variação foram altamente significativos, evidenciando diferenças entre genótipos, ambientes e a existência de um comportamento diferenciado entre os genótipos frente às variações de ambientes. O rendimento médio de grãos variou de 1321kg/ha a 801kg/ha, com média geral de 1081kg/ha. A maioria dos genótipos demonstraram alta estabilidade fenotípica, merecendo destaque os genótipos LP 93-15, LP 93,2, LP 93-38 e Rudá, os quais evidenciaram rendimento médio superior à média geral dos ensaios, adaptabilidade geral e comportamento previsível em todos os ambientes estudados. Entre os genótipos com rendimento de grãos abaixo da média geral podem ser destacados os genótipos AN 9022180, LM 93204319, LR 91155315, PF 9029975, PF 9029984 e TB 94-05, com adaptabilidade geral e alta estabilidade fenotípica nos ambientes avaliados.In the biennium 1996/97, twenty-one genotypes of colored bean were evaluated, in three environments, to identify and estimate adaptability parameters and phenotypic stability for grains yield. The experimental design was randomized blocks with three replications per treatment. The genotypes revealed highly significant differences among them, in all evaluated environments. In the analysis of joint variance, the genotype effects, environment and the interaction genotype x environments were highly significant, showing differences among genotypes x environment, and the existence of a differentiated behavior among genotypes

  14. Estabilidade da cor de geléia de jambo (Eugenia malaccensis, L. sem casca armazenada aos 25 ºC e 35 ºC na presença e ausência de luz Stability of the color of mountain apple jelly (Eugenia malaccensis, L. without rind stored at 25 ºC and 35 ºC in the presence and absence of light

    Directory of Open Access Journals (Sweden)

    Ricardo Luis Cardoso

    2008-10-01

    Full Text Available O suco de jambo sem casca foi caracterizado quanto ao pH, acidez total titulável, pectina, sólidos solúveis, relação sólidos solúveis/acidez total titulável (ATT "ratio", açúcares redutores, porcentagem de umidade. Na geléia de jambo formulada com a adição de 0,28 % de ácido cítrico e 0,4 % de pectina ATM em relação ao suco, na proporção de 50 % de açúcar (90% de sacarose e 10 % de glicose para 50 % de suco refinado, acondicionadas em copo de vidro e estocadas a 25 ºC e a 35 ºC, com e sem luz. A análise objetiva da cor foi feita por meio do espectrofotômetro CONCOR MS 1500 Plus, utilizando-se o iluminante C, ângulo de 10 graus e sistema Lab Hunter (configuração DREOL. Os dados foram submetidos à análise de variância e teste de Tukey, tendo-se isolado fatorialmente os fatores de armazenamento estudados (tempo, luz e temperatura. Foram calculados os modêlos cinéticos das variações das luminosidade (L Hunter, vermelho (aHunter e amarelo (bHunter. A geléia apresentou uma diminuição de L Hunter durante o tempo de armazenamento estocagem, menor valor na ausência de luz e maior temperatura. A cor vermelha aHunter aumentou na geléia estocada sem luz e maior temperatura. Houve um acréscimo de aHunter ao longo do tempo de armazenamento. O cálculo da cinética da luminosidade, do vermelho e do amarelo durante o período de estocagem mostrou constante de velocidade de reação de 0,01389, 0,007565 e 0,0211 respectivamente.The juice of pilled mountain apple had been characterized according to the pH, titratable acidity (AT, pectin, total soluble solids (SST, relation SST/AT - "ratio", reducing sugars and contents of moisture. In the mountain apple jelly formulated with the citric addition of acid 0,28 % of and 0.4 % of ATM pectin in relation to the juice, the ratio of 50 % of sugar (90 % of sucrose and 10 % of glucose for 50 % of fine juice, conditioned in glass cup and storedat the 25 ºC and the 35 ºC, with and

  15. Les difficultés de la filière brésilienne face à la nouvelle organisation mondiale du négoce des pierres de couleur As dificuldades da cadeia produtiva brasileira diante da nova organização do mercado mundial de gemas de cor The Brazilian commodity chain difficulties facing the new world trade organization of colored gemstones

    Directory of Open Access Journals (Sweden)

    Aurélien Reys

    2012-11-01

    Full Text Available Les filières des pierres de couleur, à l’image de la plupart des ressources naturelles exploitées, ont longtemps représenté un négoce hiérarchisé largement dominé par les principales puissances occidentales. Leur organisation serait à présent en pleine restructuration notamment sous l’influence croissante d’acteurs originaires d’Asie. La nouvelle division des tâches et la multipolarisation du commerce ne profiteraient toutefois pas à la majorité des pays extracteurs qui connaitraient toujours d’importantes difficultés à jouer un rôle autre que celui strictement en lien avec les activités d’extraction. Le Brésil, considéré comme l’une des plus grandes réserves de pierres de couleur au monde, n’aurait semble-t-il pas réussi à tirer profit de cette réorganisation du commerce. En effet, bien qu’il réussisse à l’inverse de nombreux autres pays extracteurs à tailler une partie des pierres extraites, les gemmes à l’état brut continuent de constituer une grande part de ses exportations. Cette situation se traduirait depuis quelques années par une stagnation de ses bénéfices, d’autant plus que les acteurs locaux doivent désormais faire face à de nouvelles sources de concurrence, en provenance d’Afrique de l’Est pour les activités d’extraction et de Chine pour celles de taille et de commerce. Néanmoins, l’élévation du niveau de vie des populations à l’échelle mondiale permet d’envisager à long terme une croissance positive de ce type de négoce. La cartographie mondiale du commerce des gemmes est dès lors certainement loin d’être aboutie, laissant encore une certaine marge de manœuvre pour des pays comme le Brésil, ce dernier pouvant de plus compter sur une classe moyenne nationale en pleine croissance qui pourrait à terme constituer une nouvelle source de demande.As diferentes cadeias produtivas mundiais de gemas de cor, assim como a exploração da maioria das riquezas

  16. Da cor à cor inexistente: uma reflexão sobre espectros eletrônicos e efeitos cromáticos

    Directory of Open Access Journals (Sweden)

    Toma Henrique E.

    2005-01-01

    Full Text Available Inexistent colors have been the inspiring theme of investigation by Israel Pedrosa, a Brazilian artist, who has devoted his life to creative painting, exploiting the chemical and physical effects associated with light, especially those generated in the light refraction domain. In this article, by focusing on the electronic spectra of phthalocyanines and gold nanoparticles, we discuss how such effects can influence the spectroscopic measurements, leading to inexistent bands and transitions.

  17. A cor dos têxteis Andinos: análise da cor em têxteis da cultura milenar de Paracas

    OpenAIRE

    Rodrigues, Isa Santos

    2008-01-01

    Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Conservação e Restauro Área de Têxteis O presente trabalho insere-se num projecto denominado “The color of the Andean Textiles”, que resulta de uma colaboração entre a Faculdade de Ciência e Tecnologia, da Universidade Nova de Lisboa (FCT-UNL) e o Museum of Fine Arts (MFA), de Boston. Os corantes dos têxteis da cultura de Paracas, que se desenvolveu na costa Sul d...

  18. The "Polar Light Sign" is a useful tool to detect discrete membranous supravalvular mitral stenosis.

    Science.gov (United States)

    Hertwig, Christine; Haas, Nikolaus A; Habash, Sheeraz; Hanslik, Andreas; Kececioglu, Deniz; Sandica, Eugen; Laser, Kai-Thorsten

    2015-02-01

    Mitral valve stenosis caused by a discrete supravalvular membrane is a rare congenital malformation haemodynamically leading to significant mitral valve stenosis. When the supravalvular mitral stenosis consists of a discrete supravalvular membrane adherent to the mitral valve, it is usually not clearly detectable by routine echocardiography. We report about the typical echocardiographic finding in three young patients with this rare form of a discrete membranous supravalvular stenosis caused by a membrane adherent to the mitral valve. These cases present a typical echocardiographic feature in colour Doppler generated by the pathognomonic supramitral flow acceleration. Whereas typical supravalvular mitral stenosis caused by cor triatriatum or a clearly visible supravalvular ring is easily detectable by echocardiography, a discrete supravalvular membrane adjacent to the mitral valve leaflets resembling valvular mitral stenosis is difficult to differentiate by routine echocardiography. In our opinion, this colour phenomenon does resemble the visual impression of polar lights in the northern hemisphere; owing to its typical appearance, it may therefore be named as "Polar Light Sign". This phenomenon may help to detect this anatomical entity by echocardiography in time and therefore improve the prognosis for repair.

  19. Amélie Nothomb: la vida en el cor de l’obra

    Directory of Open Access Journals (Sweden)

    Monsó, Imma

    2009-06-01

    Full Text Available Breve repaso de la obra de Amélie nothomb (autora belga nacida en Kobe, Japón en 1967, que pone de relieve la importancia de la biografía personal en las novelas de esta popular autora.

  20. Sleep-related breathing disorders in patients with schistosomal cor-pulmonale

    Directory of Open Access Journals (Sweden)

    Yehia Khalil

    2012-07-01

    Conclusion: SRBD are highly prevalent in patients with schistosomal pulmonary hypertension (PH. Also, the SA severity was correlated with more advanced PH and more severe cardiovascular impairment. Therefore in the evaluation of patients with schistosomal PH, polysomnography or an ambulatory cardiorespiratory sleep study seems justified to identify potentially treatable SRBD that may additionally challenge the already compromised cardiovascular system in these patients.