WorldWideScience

Sample records for coordinating committee activities

  1. Update of technical coordinating committee activities

    International Nuclear Information System (INIS)

    Alvarado, R.A.

    1995-01-01

    The Technical Coordinating Committee has its origins in the earliest days of implementing the Low-Level Radioactive Waste Policy Act. Between 1982 and 1985, individuals in several of the states felt that coordination among the states would be beneficial to all by affording states a cost-effective method for sharing ideas, discussing alternatives, and presenting solutions to common problems. At the current time, the committee comprises members from each of the sited states. Various compacts, federal agencies, and industry groups participate in committee activities. The Low-Level Management Program provides support for the committee through the provision of logistical support and limited manpower allocation. Activities of the committee have recently focused on waste treatment and minimization technologies. The committee also has worked diligently to see the review of the 3RSTAT computer code completed. The committee has taken a position on various regulatory proposals the past year. The committee expects to continue its work until new sites are brought online

  2. Update of technical coordinating committee activities

    Energy Technology Data Exchange (ETDEWEB)

    Alvarado, R.A.

    1995-12-31

    The Technical Coordinating Committee has its origins in the earliest days of implementing the Low-Level Radioactive Waste Policy Act. Between 1982 and 1985, individuals in several of the states felt that coordination among the states would be beneficial to all by affording states a cost-effective method for sharing ideas, discussing alternatives, and presenting solutions to common problems. At the current time, the committee comprises members from each of the sited states. Various compacts, federal agencies, and industry groups participate in committee activities. The Low-Level Management Program provides support for the committee through the provision of logistical support and limited manpower allocation. Activities of the committee have recently focused on waste treatment and minimization technologies. The committee also has worked diligently to see the review of the 3RSTAT computer code completed. The committee has taken a position on various regulatory proposals the past year. The committee expects to continue its work until new sites are brought online.

  3. Energy Materials Coordinating Committee (EMaCC)

    Energy Technology Data Exchange (ETDEWEB)

    1991-05-31

    This report summarizes EMaCC activities for fiscal year 1990 and describes the materials research programs of various offices and divisions within the department. The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the department. (JL)

  4. 77 FR 27832 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-05-11

    ... organizations --Relations with non-governmental organizations --World Maritime Day --International Maritime... DEPARTMENT OF STATE [Public Notice: 7879] Shipping Coordinating Committee; Notice of Committee...-second Session of the International Maritime Organization (IMO) Technical Co-operation Committee (TCC 62...

  5. 78 FR 57128 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-09-17

    ... agencies and the private sector, to effectively address the national priorities for non-industrial private... Coordinating Committee Web site at http://www.fs.fed.us/spf/coop/frcc/ . Visitors are encouraged to call ahead... Resource Coordinating Committee can be found by visiting the Committee's Web site at: http://www.fs.fed.us...

  6. 77 FR 76164 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-12-26

    ... atmospheric pollution --Development of international measures for minimizing the transfer of invasive aquatic... pollution hazards of chemicals and preparation of consequential amendments --Additional guidelines for... DEPARTMENT OF STATE [Public Notice 8133] Shipping Coordinating Committee; Notice of Committee...

  7. 78 FR 32698 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-05-31

    ... DEPARTMENT OF STATE [Public Notice 8340] Shipping Coordinating Committee; Notice of Committee... Technical Co-operation Committee --Protection of vital shipping lanes --Periodic review of administrative... of the Organization since the twenty-eighth regular session of the Assembly --External relations...

  8. 78 FR 73819 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-12-09

    ... DEPARTMENT OF AGRICULTURE Forest Service Forest Resource Coordinating Committee AGENCY: Forest Service, USDA. ACTION: Notice of Cancellation. SUMMARY: The U.S. Department of Agriculture, Forest Service was required to cancel the October 17-18, 2013 meeting of the Forest Resource Coordinating Committee...

  9. Second meeting of the ITPA Coordinating Committee

    International Nuclear Information System (INIS)

    Campbell, D.J.; Shimada, M.

    2002-01-01

    The second meeting of the International Tokamak Physics Activity (ITPA) Coordinating Committee (CC), consisting of representatives from the ITPA participants and the topical physics group chairs and co-chairs was held at GA Technologies, San Diego, USA on 1-2 March 2002. The purpose of the meeting was to review the progress of physics R and D, especially in the high priority research ares, for burning plasma experiments including ITER, and to discuss the plans for pursuing necessary R and D. CC heard reports on the most recent developments in the areas of responsibility of the topical groups

  10. 78 FR 58596 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-09-24

    ... DEPARTMENT OF STATE [Public Notice 8481] Shipping Coordinating Committee; Notice of Committee... --External relations --Report on the status of the Convention and membership of the Organization --Report on... performs functions --Supplementary agenda items, if any The agenda items for A 28, to be considered include...

  11. Federal Energy Resources Modernization Coordinating Committee

    Energy Technology Data Exchange (ETDEWEB)

    Parker, G. B.

    1992-07-01

    This report summarizes the broad range of activities supported by Federal Energy Management Program (FEMP) and other federal agencies focused on meeting the President's Executive Order on Federal Energy Management promulgated to meet energy savings goals and encourage more efficient management of all federal energy resources. These activities are reported semiannually under the auspices of the FERM Coordinating Committee, and as such include activities undertaken from October 1, 1991, through March 31, 1992. The activities reported are classified into four major categories: (1) technology-base support, which includes development of processes, software, metering and monitoring equipment and strategies, and other tools for the federal energy manager to better understand and characterize their energy resources; (2) federal energy systems testing and monitoring; (3) federal energy systems modernization projects at federal installations in cooperation with the utilities serving the sites; and (4) energy supply, distribution and end-use conservation assessment for federal agencies and/or facilities.

  12. The committee of scientific expertise coordination

    International Nuclear Information System (INIS)

    2003-01-01

    Placed under the MIES control, the Committee of scientific expertise coordination defines the needs, the contain and the planing of expertises realized in function of Climate national and international decisions and negotiations calendars. The Committee verifies the different expertises and offers the administrations, scientific tools and techniques useful for the negotiations. It can also define long-dated research needs which require the scientific community mobilization. This paper provides some document of the Committee: objectives, operating and priorities of the Committee, scenarios ''Factor 4'' and ''crack technology'', perceptions and practices, developing countries (China, India...), Euromed. (A.L.B.)

  13. 77 FR 47490 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-08-08

    ...: --Adoption of the agenda --Decisions of other IMO bodies --Global Maritime Distress and Safety System (GMDSS... facilities --Consideration of operational and technical coordination provisions of maritime safety... Vice-Chairman for 2014 --Any other business --Report to the Maritime Safety Committee Members of the...

  14. 77 FR 72431 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-12-05

    ... other IMO bodies --Global Maritime Distress and Safety System (GMDSS): --Review and modernization of the... operational and technical coordination provisions of maritime safety information (MSI) services, including the... business --Report to the Maritime Safety Committee Members of the public may attend this meeting up to the...

  15. 77 FR 778 - Council Coordination Committee Meeting

    Science.gov (United States)

    2012-01-06

    ... Coordination Committee Meeting AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and... Resources, Habitat Blueprint, Managing Our Nations III Conference, and other topics related to... p.m.--Habitat Blueprint. 2:30 p.m.-3:30 p.m.--Managing Our Nation's Fisheries (MONF) III Conference...

  16. 78 FR 29201 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-05-17

    ... the International Maritime Organization's (IMO) Marine Safety Committee to be held at the IMO... session of the Sub-Committee) Technical co-operation activities relating to maritime safety and security... amendments to mandatory instruments Measures to enhance maritime security Goal-based new ship construction...

  17. 77 FR 57638 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-09-18

    ... the International Maritime Organization's (IMO) Marine Safety Committee to be held at the IMO... seventeenth session of the Sub-Committee); Technical co-operation activities relating to maritime safety and... amendments to mandatory instruments; Measures to enhance maritime security; Goal-based new ship construction...

  18. 78 FR 37781 - Forest Resource Coordinating Committee; Meeting

    Science.gov (United States)

    2013-06-24

    ... DEPARTMENT OF AGRICULTURE Forest Service Forest Resource Coordinating Committee; Meeting AGENCY: Forest Service, USDA. ACTION: Notice of meeting; Correction. SUMMARY: The Forest Service published a... teleconference line. FOR FURTHER INFORMATION CONTACT: Maya Solomon, Forest Resource Coordinating Committee...

  19. Activities of the research committee

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, A.; Shirai, T.; Nakagawa, M.; Osugi, T.; Ikeda, Y.; Ishida, T.; Shimazaki, J. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2000-01-01

    The department of Nuclear Energy System serves as a secretarial of the following four research committees organized by JAERI; Japanese Nuclear Data Committee, Atomic and Molecular Data Research Committee, Research Committee on Reactor Physics and Research Committee on Marine Reactors. The purpose and the expected task of each committee are summarized here. The detailed activities of each committee are presented in this paper. (author)

  20. 78 FR 34035 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-06-06

    ...-industrial private forestry activities within the Department of Agriculture and with the private sector. The... Committee Web site, http://www.fs.fed.us/spf/coop/frcc/ , and written comments will be accepted up to the... Independence Ave. SW., Mailstop 1123, Washington, DC 20250 or by email to [email protected]us . All comments...

  1. Energy Materials Coordinating Committee, fiscal year 1997. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. This report summarizes EMaCC activities for FY 1997 and describes the materials research programs of various offices and divisions within the Department.

  2. 75 FR 27614 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-05-17

    ... Environment Protection Committee. --Consideration of the report of the Maritime Safety Committee... Session of the International Maritime Organization (IMO) Council to be held at the IMO headquarters in... HNS Convention. --World Maritime University: --IMO International Maritime Law Institute: --Protection...

  3. Current projects of the National Wind Coordinating Committee

    Energy Technology Data Exchange (ETDEWEB)

    Rhoads, H. [National Wind Coordinating Committee, Washington, DC (United States)

    1997-12-31

    This paper summarizes the activities of the National Wind Coordinating Committee (NWCC), a multi-stakeholder collaborative formed in 1994 to support the responsible use of wind power in the USA. The NWCC`s vision is a self-sustaining commercial market for wind power - environmentally, economically, and politically sustainable. Current NWCC activities include: outreach initiatives, disseminating information about wind energy to regulators and legislators through the Wind Energy Issue Paper Series, researching distributed wind energy models, producing a wind facility permitting handbook, improving avian research, addressing transmission and resource assessment issues, and exploring sustainable development and marketing approaches.

  4. 75 FR 32472 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-06-08

    ... Coordinator for Health Information Technology AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of committee recommendations and invitation for public input... Coordinator for Health Information Technology (ONC). Name of Committee: HIT Standards Committee. General...

  5. Third meeting of the ITPA Co-ordinating Committee

    International Nuclear Information System (INIS)

    Campbell, D.J.; Shimada, M.

    2003-01-01

    The third meeting of the ITPA (International Tokamak Physics Activity) coordinating committee (CC), held on 24-25 October 2002 at the Max-Planck-Institut fuer Plasmaphysik, Garching. Dr. D.Campbell, Chair of the CC, noted the significant enhancement of the physics basis for burning plasma experiments, which had been achieved via the ITPA collaboration. He reported about successful assessment the ITER diagnostics requirements through ITPA Topical Groups. Dr. Aymar, ITER international team leader, summarized the status of ITER. The Topical Group chairs reported on the most significant recent developments in their areas of responsibility

  6. 76 FR 19176 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-04-06

    ...) Maritime Safety Committee (MSC 89) to be held May 11-20, 2011. The primary matters to be considered at MSC... --Technical assistance sub-programme in maritime safety and security --Capacity-building for the... business --Report of the Maritime Safety Committee Members of the public may attend these two meetings up...

  7. 78 FR 32699 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-05-31

    ... Session of the International Maritime Organization's (IMO) Sub-Committee on Safety of Navigation to be... --Report to the Maritime Safety Committee Members of the public may attend this meeting up to the seating... system ``BeiDou'' in the maritime field --International Telecommunication Union (ITU) matters, including...

  8. 77 FR 47491 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-08-08

    ... to the Maritime Safety Committee Members of the public may attend this meeting up to the seating... Session of the International Maritime Organization's (IMO) Sub-Committee on Dangerous Goods, Solid Cargoes... --Amendment 37-14 to the International Maritime Dangerous Goods (IMDG) Code and supplements, including...

  9. 75 FR 63888 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-10-18

    ... Work Methods and Organization of Work of the Legal Committee --Any other business --Consideration of... for the ninety-seventh Session of the International Maritime Organization's (IMO) Legal Committee to... Pollution Damage, 2001 --Consideration of a proposal to amend the limits of liability of the 1996 Protocol...

  10. 76 FR 12787 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-03-08

    ... --Any other business. --The public should be aware that Legal Committee has received a proposal to... the International Maritime Organization's (IMO) Legal Committee to be held at the IMO headquarters in... treatment of seafarers in the event of a maritime accident; --Consideration of a proposal to amend the...

  11. 78 FR 70391 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-11-25

    ... of the International Maritime Organization's (IMO) Sub- Committee on Ship Design and Construction to... vessels --Carriage of more than 12 industrial personnel on board vessels engaged in international voyages...

  12. 77 FR 28923 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-05-16

    ... Session of the International Maritime Organization's (IMO) Sub-Committee on Safety of Navigation to be... --Election of Chairman and Vice-Chairman for 2013 --Any other business --Report to the Maritime Safety...

  13. 75 FR 64390 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-10-19

    ...-eighth Session of the International Maritime Organization's (IMO) Maritime Safety Committee to be held at... --Technical assistance sub-programme in maritime safety and security --Capacity-building for the... --Measures to enhance maritime security --Goal-based new ship construction standards --LRIT-related matters...

  14. 76 FR 58330 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-09-20

    ... bodies --Global Maritime Distress and Safety System (GMDSS) --ITU maritime radiocommunication matters... for 2013 --Any other business --Report to the Maritime Safety Committee Finally, an open meeting will... events at the International Maritime Organization (IMO) in London, United Kingdom. Two of these meetings...

  15. 77 FR 21619 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-04-10

    ... of the International Maritime Organization's (IMO) Marine Safety Committee to be held at the IMO... gases; Implementation of the STCW Convention; Technical assistance sub-programme in maritime safety and...: Consideration and adoption of amendments to mandatory instruments; Measures to enhance maritime security; Goal...

  16. 78 FR 77773 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-12-24

    ... of the International Maritime Organization's (IMO) Sub-Committee on Human Element, Training and... to be considered include: --Decisions of other IMO bodies --Validation of model training courses... --Development of guidelines for wing-in-ground craft --Role of the human element --Development of guidance for...

  17. 78 FR 17466 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-03-21

    ... forty-fourth Session of the International Maritime Organization's (IMO) Sub-Committee on Standards of... of other IMO bodies --Validation of model training courses --Unlawful practices associated with... Vessel Personnel (STCW-F), 1995 --Development of Guidelines for wing-in-ground (WIG) craft --Role of the...

  18. 78 FR 77772 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-12-24

    ... emissions of Black Carbon from international shipping --Review of relevant non-mandatory instruments as a... should contact the meeting coordinator, Mr. Timothy Brown, by email at timothy.m.brown@uscg.mil , by...

  19. 75 FR 35873 - Meeting; Shipping Coordinating Committee

    Science.gov (United States)

    2010-06-23

    ... Report. --Status of Constituent and Other Instruments. --Global Maritime Distress and Safety Systems... Vice-Chairman for 2012. --Any other business. --Report to the Maritime Safety Committee. The primary... purpose of the July 28 SHC meeting is to prepare for the fifty-third Session of the International Maritime...

  20. INFCE technical co-ordinating committee documents

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    A collection of the documents covering the period December 1977 through February 1980 submitted to or generated by the Technical Co-ordinating Comittee is presented. The documents cover primarily the organizational aspects of INFCE, but conclusions from the various Working Groups are summarized.

  1. INFCE technical co-ordinating committee documents

    International Nuclear Information System (INIS)

    A collection of the documents covering the period December 1977 through February 1980 submitted to or generated by the Technical Co-ordinating Comittee is presented. The documents cover primarily the organizational aspects of INFCE, but conclusions from the various Working Trays are summarized

  2. 77 FR 260 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2012-01-04

    ... USDA and the broader forestry sector, with specific focus on owners of non-industrial private... Coordinator, by phone at (202) 205-1376 or by email at [email protected]us or Ted Beauvais, FRCC Designted Federal Officer, by phone (202) 205-1190 or by email at [email protected]us . Individuals who use...

  3. 78 FR 6806 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-01-31

    .... Department of Agriculture, and coordination with State agencies and the private sector, to effectively address the national priorities for non- industrial private forest land. The purpose of the meeting is... [email protected]us . All comments, including names and addresses when provided, are placed in the record...

  4. 78 FR 73819 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-12-09

    ..., Conservation, and Energy Act of 2008 (Pub. L. 110-246). Additional information on the Forest Resource... into the Whitten Building. FOR FURTHER INFORMATION CONTACT: Maya Solomon, Forest Resource Coordinating... forest health, and landscape scale conservation and management. The meeting is open to the public. All...

  5. 20 CFR 631.37 - Coordination activities.

    Science.gov (United States)

    2010-04-01

    ... TITLE III OF THE JOB TRAINING PARTNERSHIP ACT State Administration § 631.37 Coordination activities. (a..., including the formation of labor-management committees under this part, the dislocated worker unit shall... Training Act (29 U.S.C. 1721 note), title IV-C of the Job Training Partnership Act (29 U.S.C. 1721, et seq...

  6. Energy Materials Coordinating Committee (EMaCC), Fiscal year 1990

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1991-05-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. Four topical subcommittees are established and are continuing their own programs: Structural Ceramics, Electrochemical Technologies, Radioactive Waste Containment, and Superconductivity. In addition, the EMaCC aids in obtaining materialsrelated inputs for both intra- and inter-agency compilations. Membership in the EMaCC is open to any Department organizational unit; participants are appointed by Division or Office Directors. The current active membership is listed on the following four pages. The EMaCC reports to the Director of the Office of Energy Research in his capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1990 and describes the materials research programs of various offices and divisions within the Department. The Chairman of EMaCC for FY 1990 was Scott L. Richlen; the Executive Secretary was Dr. Jerry Smith.

  7. The committee of scientific expertise coordination; Le comite de coordination d'expertise scientifique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    Placed under the MIES control, the Committee of scientific expertise coordination defines the needs, the contain and the planing of expertises realized in function of Climate national and international decisions and negotiations calendars. The Committee verifies the different expertises and offers the administrations, scientific tools and techniques useful for the negotiations. It can also define long-dated research needs which require the scientific community mobilization. This paper provides some document of the Committee: objectives, operating and priorities of the Committee, scenarios ''Factor 4'' and ''crack technology'', perceptions and practices, developing countries (China, India...), Euromed. (A.L.B.)

  8. The committee of scientific expertise coordination; Le comite de coordination d'expertise scientifique

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    Placed under the MIES control, the Committee of scientific expertise coordination defines the needs, the contain and the planing of expertises realized in function of Climate national and international decisions and negotiations calendars. The Committee verifies the different expertises and offers the administrations, scientific tools and techniques useful for the negotiations. It can also define long-dated research needs which require the scientific community mobilization. This paper provides some document of the Committee: objectives, operating and priorities of the Committee, scenarios ''Factor 4'' and ''crack technology'', perceptions and practices, developing countries (China, India...), Euromed. (A.L.B.)

  9. Final report of the Committee on Interagency Radiation Research and Policy Coordination, 1984-1995

    International Nuclear Information System (INIS)

    1995-09-01

    This document is the final report of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). The committee was established to address national and international issues involving ionizing and nonionizing radiation. Three sections are included in the report: a summary of CIRRPC's history structure, and operations; CIRRPC's most significant activities, findings and recommendations on national radiation issues of sufficient importance and scope to require interagency attention; topics for future consideration by Federal agencies

  10. Final report of the Committee on Interagency Radiation Research and Policy Coordination, 1984-1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This document is the final report of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). The committee was established to address national and international issues involving ionizing and nonionizing radiation. Three sections are included in the report: a summary of CIRRPC`s history structure, and operations; CIRRPC`s most significant activities, findings and recommendations on national radiation issues of sufficient importance and scope to require interagency attention; topics for future consideration by Federal agencies.

  11. Energy Materials Coordinating Committee (EMaCC). Fiscal year 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-31

    The committee serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. This is accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops involving DOE and major contractors. The program descriptions consist of a funding summary for each Assistant Secretary office and the Office of Energy Research, and detailed project summaries with project goals and accomplishments. A FY 1994 budget summary table for each program is included. A directory and a keyword index is included at the end of this document.

  12. 29 CFR 42.20 - Regional Farm Labor Coordinated Enforcement Committee.

    Science.gov (United States)

    2010-07-01

    ... Coordinated Enforcement Committee. (a) Under the leadership of the ESA Regional Administrator, each region... Committee shall: (1) Meet regularly on at least a quarterly basis; (2) Exchange information on enforcement...

  13. Energy Materials Coordinating Committee (EMaCC) Fiscal Year 1999 annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-10-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. This report summarizes EMaCC activities for FY 1999 and describes the materials research programs of various offices and divisions within the Department.

  14. Energy Materials Coordinating Committee (EMaCC): Annual technical report, Fiscal year 1987

    International Nuclear Information System (INIS)

    1988-09-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1987 and describes the materials research programs of various offices and divisions within the Department

  15. 75 FR 29993 - Department of Commerce: Trade Promotion Coordinating Committee Renewable Energy and Energy...

    Science.gov (United States)

    2010-05-28

    ... Coordinating Committee Renewable Energy and Energy Efficiency Export Strategy To Support the National Export... Trade Promotion Coordinating Committee's (TPCC) Renewable Energy and Energy Efficiency Working Group is developing a U.S. Renewable Energy and Energy Efficiency Export Strategy (the Strategy) to guide U.S...

  16. 75 FR 6398 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-02-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the National Coordinator for Health Information Technology; HIT Policy Committee's Adoption/Certification Workgroup Meeting; Notice of Meeting AGENCY: Office... of Committee: HIT Policy Committee's Adoption/Certification Workgroup. General Function of the...

  17. 75 FR 70923 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee...

  18. 75 FR 16126 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-03-31

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... and Coordination, Office of the National Coordinator for Health Information Technology. [FR Doc. 2010...

  19. 75 FR 151 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-01-04

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Programs and Coordination Office of the National Coordinator for Health Information Technology. [FR Doc. E9...

  20. Committee on Interagency Radiation Research and policy coordination - first annual report, June 30, 1985

    International Nuclear Information System (INIS)

    1985-01-01

    This is the first annual report of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). CIRRPC was established on April 9, 1984, by Dr. George A. Keyworth, II, Science Advisor to the President and Director of the Office of Science and Technology Policy (OSTP). CIRRPC replaced the Committee on Interagency Radiation Policy and was assigned responsibilities of the former Interagency Radiation Research Committee and former Radiation Policy Council. CIRRPC is chartered under the Federal Coordinating Council for Science, Engineering and Technology (FCCSET). Its overall charge is to coordinate radiation matters between agencies, evaluate radiation matters between agencies, evaluate radiation research, and provide advice on the formulation of radiation policy

  1. Energy Materials Coordinating Committee (EMaCC): Annual technical report, fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. This report summarizes EMaCC activities for FY 1993 and describes the materials research programs of various offices and divisions within the Department. The program descriptions consist of a funding summary for each Assistant Secretary office and the Office of Energy Research, and detailed project summaries with project goals and accomplishments. The FY 1993 budget summary table for DOE Materials Activities in each of the programs is presented.

  2. The National Wind Coordinating Committee : a model for consensus building around renewable technologies

    Energy Technology Data Exchange (ETDEWEB)

    Holt, E.A. [Ed Holt and Associates Inc., Harpswell, ME (United States); Rhoads, H.E. [RESOLVE Inc., Washington, DC (United States)

    1998-05-01

    The role of the U.S. National Wind Coordinating Committee (NWCC), its main activities, key accomplishments and operational methods were described. The NWCC is a collaborative of representatives from the utility, wind industry, environmental, consumer, regulatory, power marketer, state and federal government sectors. Their main objective is to identify issues that impact the use of wind power. As one of its accomplishments, the NWCC has published a Permitting Handbook which describes the general features of a wind project and provides help for the basic steps in planning, permitting, construction, operation and closure of a wind facility.

  3. 11 CFR 109.33 - May a political party committee assign its coordinated party expenditure authority to another...

    Science.gov (United States)

    2010-01-01

    ... Elections FEDERAL ELECTION COMMISSION GENERAL COORDINATED AND INDEPENDENT EXPENDITURES (2 U.S.C. 431(17... 11 Federal Elections 1 2010-01-01 2010-01-01 false May a political party committee assign its... committee includes a subordinate committee of a State committee and includes a district or local committee...

  4. Energy Materials Coordinating Committee (EMaCC): Fiscal year 1996. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. The EMaCC reports to the Director of the Office of Energy Research in his or her capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1996 and describes the materials research programs of various offices and divisions within the Department.

  5. Energy Materials Coordinating Committee (EMaCC): Fiscal year 1996. Annual technical report

    International Nuclear Information System (INIS)

    1997-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. The EMaCC reports to the Director of the Office of Energy Research in his or her capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1996 and describes the materials research programs of various offices and divisions within the Department

  6. 76 FR 1432 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2011-01-10

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of Meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  7. 75 FR 8954 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-02-26

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  8. 75 FR 70923 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  9. 75 FR 29761 - Office of the National Coordinator for Health Information Technology: HIT Standards Committee...

    Science.gov (United States)

    2010-05-27

    ... Technology: HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  10. 76 FR 4354 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2011-01-25

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  11. 75 FR 16126 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-03-31

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  12. 75 FR 151 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-01-04

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  13. 76 FR 9784 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2011-02-22

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  14. 75 FR 65486 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-10-25

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  15. 75 FR 29762 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-05-27

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  16. 75 FR 51820 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-08-23

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  17. 75 FR 8953 - Office of the National Coordinator for Health Information Technology HIT Policy Committee...

    Science.gov (United States)

    2010-02-26

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... a policy framework for the development and adoption of a nationwide health information technology...

  18. 76 FR 4352 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2011-01-25

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  19. 75 FR 5595 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-02-03

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  20. 75 FR 51819 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-08-23

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health [[Page 51820

  1. 75 FR 57026 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-09-17

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  2. 75 FR 42091 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-07-20

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee... framework for the development and adoption of a nationwide health information technology infrastructure that...

  3. Federal Energy Resources Modernization Coordinating Committee. Semiannual Report, October 1, 1991 Through March 31, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Parker, G B

    1992-07-01

    This report summarizes the broad range of activities supported by Federal Energy Management Program (FEMP) and other federal agencies focused on meeting the President`s Executive Order on Federal Energy Management promulgated to meet energy savings goals and encourage more efficient management of all federal energy resources. These activities are reported semiannually under the auspices of the FERM Coordinating Committee, and as such include activities undertaken from October 1, 1991, through March 31, 1992. The activities reported are classified into four major categories: (1) technology-base support, which includes development of processes, software, metering and monitoring equipment and strategies, and other tools for the federal energy manager to better understand and characterize their energy resources; (2) federal energy systems testing and monitoring; (3) federal energy systems modernization projects at federal installations in cooperation with the utilities serving the sites; and (4) energy supply, distribution and end-use conservation assessment for federal agencies and/or facilities.

  4. 76 FR 67747 - Interagency Autism Coordinating Committee; Call for Nominations

    Science.gov (United States)

    2011-11-02

    ... shall be made without discrimination on the basis of age, race, ethnicity, gender, sexual orientation... the committee's function. Every effort is made to ensure that the views of women, all ethnic and...

  5. CIRRPC (Committee on Interagency Radiation Research and Policy Coordination) sixteenth quarterly report, April 1-June 30, 1988

    International Nuclear Information System (INIS)

    Young, A.L.

    1988-01-01

    The document is a summary of the Committee on Interagency Radiation Research and Policy Coordination activities for the period April 1 through June 30, 1988. During the reporting period, the Executive Committee met with the staff concerned with the radiation matters of the Department of the Interior on May 20 and with the Department of Defense on May 23 to review current CIRRPC activities and issues of particular interest to those agencies. The meetings were a part of CIRRPC's program of visits to member agencies on a two-year cycle

  6. 75 FR 33811 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-06-15

    ... Technology; HIT Policy Committee's Privacy & Security Tiger Team Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This... National Coordinator for Health Information Technology (ONC). The meeting will be open to the public. Name...

  7. 75 FR 17744 - Office of the National Coordinator for Health Information Technology HIT Policy Committee...

    Science.gov (United States)

    2010-04-07

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of change of location for meetings. This... Coordinator for Health Information Technology (ONC). The meeting will be open to the public. Name of Committee... health information technology infrastructure that permits the electronic exchange and use of health...

  8. 75 FR 65551 - Shipping Coordinating Committee; Notice of Subcommittee Meeting

    Science.gov (United States)

    2010-10-25

    ... from passenger ships. --Review of damage stability regulations for ro-ro passenger ships. --Legal and... SOLAS chapter II-1 subdivision and damage stability regulations. --Consideration of IACS unified... 2012. --Any other business. --Report to the Maritime Safety Committee. Members of the public may attend...

  9. Energy materials coordinating committee (EMACC) Fiscal Year 1980. Annual technical report

    International Nuclear Information System (INIS)

    1980-01-01

    This report contains information on the FY 1980 Department of Energy materials research and development programs and on those programs/projects with a significant materials activity. It was compiled by the Energy Materials Coordinating Committee (EMaCC). The previous report in this series summarized the FY 1979 programs (DOE/US-0002-2). The report is separated into sections, each containing programs reporting to one of six Assistant Secretaries of the Department: Conservation and Solar Energy, Defense Programs, Environment, Fossil Energy, Nuclear Energy, and Resource Applications; and one section, Energy Research, responsible to the Director of the Office of Energy Research. For convenience in locating the generic types of materials activities, an Appendix has been added that contains a primary keyword index

  10. Energy materials coordinating committee (EMACC) Fiscal Year 1980. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    This report contains information on the FY 1980 Department of Energy materials research and development programs and on those programs/projects with a significant materials activity. It was compiled by the Energy Materials Coordinating Committee (EMaCC). The previous report in this series summarized the FY 1979 programs (DOE/US-0002-2). The report is separated into sections, each containing programs reporting to one of six Assistant Secretaries of the Department: Conservation and Solar Energy, Defense Programs, Environment, Fossil Energy, Nuclear Energy, and Resource Applications; and one section, Energy Research, responsible to the Director of the Office of Energy Research. For convenience in locating the generic types of materials activities, an Appendix has been added that contains a primary keyword index.

  11. Committee on Interagency Radiation Research and Policy Coordination 10th anniversary report

    International Nuclear Information System (INIS)

    1994-06-01

    Ten years ago, on April 9, 1984, the Science Advisor to the President, and Director of the Office of Science and Technology Policy, established the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC) to meet the need for an interagency committee to address Congressionally mandated and agency-identified issues related to radiation research and policy. CIRRPC replaced the Committee on Interagency Radiation Policy, a committee of the Federal Coordinating Council for Science, Engineering and Technology, and assumed the responsibilities of the Interagency Radiation Research Committee and the Radiation Policy Council, whose charters had expired. Since then, CIRRPC has been recognized as an effective and respected mechanism for coordinating radiation policy among Federal agencies and as an efficient coordinator and evaluator of Federal efforts on designated radiation research projects. In the last 10 years, CIRRPC has established various Policy and Science Subpanels to undertake the oftentimes difficult task of resolving and coordinating agency policies and responses to issues dealing with radiation. These subpanels addressed such issues as the metrication of radiation units, the policy impact of the radioepidemiological tables, naturally occurring and accelerator-produced radioactive materials, radon protection and health effects, predisaster planning for human health effects research, and ionizing radiation risk assessment. These subpanels and their work represent CIRRPC's continuing effort to seek a common position on issues of national significance and interest

  12. Energy Materials Coordinating Committee (EMACC). Annual Technical Report, Fiscal Year 1978

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1978-08-01

    The Department of Energy Materials Coordinating Committee (EMACC) completed its first year of activity in FY 1978. A major project during the year was to conduct a survey of topical areas and prepare the report, Survey and Analysis of Selected Topics within the Department of Energy's Materials Research and Development Programs. Seven topics selected were those that had a high level of Divisional interest and supplement those reported in FY 1977 in DOE/ET-0006. The topics and the EMACC panel leaders in charge of compiling information were: 1. Joining of Materials, E.E. Hoffman and E. Dalder; 2. Elastomers R. Nelson; 3. Catalysts and Catalytic Effects R. Epple; 4. Radiation Effects K. Zwilsky; 5. Superconductivity W. Clinton; 6. Cement and Concrete L. Kukacka BNL/R. Reeber; and 7. Alternate Materials R.R. Reeber The report summarizes over 250 projects in these areas and completes the initial review started by James Swisher FY 1977 EMACC Chairman.

  13. Energy Materials Coordinating Committee (EMaCC). Annual technical report, Fiscal Year 2001

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations.

  14. 75 FR 8078 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-02-23

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  15. 76 FR 1432 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2011-01-10

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  16. 75 FR 369 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-01-05

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  17. 75 FR 51818 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-08-23

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  18. 75 FR 12752 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-03-17

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of Meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  19. 75 FR 65486 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-10-25

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  20. 75 FR 21630 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-04-26

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  1. 75 FR 57025 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-09-17

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  2. 75 FR 36658 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-06-28

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  3. 75 FR 8079 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-02-23

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  4. 76 FR 4353 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2011-01-25

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  5. 75 FR 12753 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-03-17

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  6. 75 FR 36657 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-06-28

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  7. 76 FR 1433 - Office of the National Coordinator for Health Information Technology HIT Standards Committee's...

    Science.gov (United States)

    2011-01-10

    ... Technology HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  8. 75 FR 70925 - Office of the National Coordinator for Health Information Technology; HIT; Standards Committee's...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT; Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  9. 75 FR 29761 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-05-27

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  10. 75 FR 368 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-01-05

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  11. 75 FR 3905 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee's...

    Science.gov (United States)

    2010-01-25

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  12. 75 FR 70924 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  13. 75 FR 34141 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-06-16

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access...

  14. Energy materials coordinating committee (EMACC) Fiscal Year 1982. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1983-03-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/ workshops on selected topics involving both DOE and major contractors. In addition, the EMaCC aids in obtaining materials - related inputs for both intra- and interagency compilations. Membership in the EMaCC is open to any Department organizational unit; participants are appointed by Division or Office Directors. The current membership is listed in Table 1. The EMACC reports to the Director of the Office of Energy Research in his capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMACC terms of reference. In this report are described 1) EMACC activities for FY 1982; 2) a summary of materials funding in the Department from FY 1978 to the present; and 3) on-going materials programs in the Department.

  15. Hydrogen Energy Coordinating Committee annual report: Summary of DOE hydrogen programs for FY 1991

    International Nuclear Information System (INIS)

    1991-07-01

    The HECC was established over 13 years ago to ensure that the many varied aspects of hydrogen technology within the Department are coordinated. Each year the committee brings together technical representative within the Department to coordinate activities, share research results and discuss future priorities and directions. This FY 1990 summary is the thirteenth consecutive yearly report. It provides an overview of the hydrogen-related programs of the DOE offices represented in the HECC for the fiscal year. For the purposes of this report, the research projects within each division have been organized into two categories: Fuels-related Research and Non-fuels-related Research. An historical summary of the hydrogen budgets of the several divisions is given. Total DOE funding in FY 1990 was $6.8 million for fuels-related research and $32.9 million for non-fuels-related research. The individual program elements are described in the body of this report, and more specific program information can be found in the Technology Summary Forms in Appendix A

  16. 5 CFR 950.104 - Local Federal Coordinating Committee responsibilities.

    Science.gov (United States)

    2010-01-01

    ... participate in the campaign. (12) Bringing allegations of coercion to the attention of the Director and the... not use the services of consulting firms, advertising firms or similar business organizations to... activities including: Public notice in newspapers, postings on Web sites, advertising in trade journals...

  17. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2004

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2005-08-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The FY 2004 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2004 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2004 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  18. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2002

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2003-08-08

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The EMaCC Charter and the memorandum approving it are presented in the Appendix of this report. The FY 2002 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2002 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2002 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  19. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2005

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2006-09-29

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The FY 2004 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2004 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2004 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  20. Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

    Energy Technology Data Exchange (ETDEWEB)

    None

    1985-07-01

    The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985.

  1. Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

    International Nuclear Information System (INIS)

    1985-07-01

    The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985

  2. French butane propane committee. 2003 activity report

    International Nuclear Information System (INIS)

    2003-01-01

    This activity report presents the French butane-propane committee (CFBP), an association for the promotion of liquefied petroleum gases (LPG), the characteristics of LPG fuels, the LPG market and its evolution, the CFBP's missions and the 2003 highlights: representation of subscribing companies, participation to standardization works, making techniques and regulations change, improving the safety of equipments and installations, training and information, promoting LPG products. (J.S.)

  3. French butane propane committee. 2004 activity report

    International Nuclear Information System (INIS)

    2004-01-01

    This activity report presents the French butane-propane committee (CFBP), an association for the promotion of liquefied petroleum gases (LPG), the characteristics of LPG fuels, the LPG market and its evolution, the CFBP's missions and the 2004 highlights: representation of subscribing companies, participation to standardization works, making techniques and regulations change, improving the safety of equipments and installations, training and information, promoting LPG products. (J.S.)

  4. Coordinated Voltage Control of Active Distribution Network

    Directory of Open Access Journals (Sweden)

    Xie Jiang

    2016-01-01

    Full Text Available This paper presents a centralized coordinated voltage control method for active distribution network to solve off-limit problem of voltage after incorporation of distributed generation (DG. The proposed method consists of two parts, it coordinated primal-dual interior point method-based voltage regulation schemes of DG reactive powers and capacitors with centralized on-load tap changer (OLTC controlling method which utilizes system’s maximum and minimum voltages, to improve the qualified rate of voltage and reduce the operation numbers of OLTC. The proposed coordination has considered the cost of capacitors. The method is tested using a radial edited IEEE-33 nodes distribution network which is modelled using MATLAB.

  5. Energy Materials Coordinating Committee (EMaCC). Annual Technical Report, Fiscal Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2001-07-31

    The Energy Materials Coordinating Committee Annual Report (attached, DOE/SC-0040) provides an annual summary of non-classified materials-related research programs supported by various elements within the Department of Energy. The EMaCC Annual Report is a useful working tool for project managers who want to know what is happening in other divisions, and it provides a guide for persons in industry and academia to the materials program within the Department. The major task of EMaCC this year was to make the Annual Report a more user-friendly document by removing redundant program information and shortening the project summaries.

  6. Coordination and standardization of federal sedimentation activities

    Science.gov (United States)

    Glysson, G. Douglas; Gray, John R.

    1997-01-01

    In August 1964, the Bureau of the Budget issued Circular A-67 to set forth guidelines for the coordination of water-data acquisition activities throughout the Federal government. The U.S. Department of the Interior was assigned the task of implementing Circular A-67, which in turn redelegated this responsibility to the U.S. Geological Survey (USGS). Delegation of the lead responsibility for water-data coordination to the USGS occurred because of its historical role as the primary agency for water-data acquisition in the United States. To provide overall leadership for implementing the provisions of Circular A-67, the USGS established the Office of Water Data Coordination in the Water Resources Division (WRD). In addition, regional and district offices of the WRD were delegated responsibility for coordinating water data within their geographic areas of responsibility. On December 10, 1991, the Office of Management and Budget issued OMB Number Memorandum M-92-01, which expands the USGS's coordination role to encompass all water information. This includes data critical to water resources in the following categories: - surface- and ground-water quality and quantity,

  7. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2003

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-10-18

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed.

  8. Committee on Interagency Radiation Research and Policy Coordination second annual report, July 1, 1985--June 30, 1986

    Energy Technology Data Exchange (ETDEWEB)

    Young, A.L.

    1996-06-30

    This is the second annual report of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). CIRRPC was established on April 9, 1984, to replace the Committee on Interagency Radiation Policy and was assigned responsibilities of the former Interagency Radiation Research Committee and former Radiation Policy Council. CIRRPC is chartered under the Federal Coordinating Council for Science, Engineering and Technology (FCCSET) and reports to the Office of Science and Technology Policy (OSTP), Executive Office of the President. Its overall charge is to coordinate radiation matters between agencies, evaluate radiation research, and provide advice on the formulation of radiation policy. During CIRRPC`s second year, the member agencies have called upon this interagency resource to assist in coordinating science and policy issues and to provide a vehicle to accomplish multiagency tasks.

  9. Committee on Interagency Radiation Research and Policy Coordination second annual report, July 1, 1985--June 30, 1986

    International Nuclear Information System (INIS)

    Young, A.L.

    1996-01-01

    This is the second annual report of the Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). CIRRPC was established on April 9, 1984, to replace the Committee on Interagency Radiation Policy and was assigned responsibilities of the former Interagency Radiation Research Committee and former Radiation Policy Council. CIRRPC is chartered under the Federal Coordinating Council for Science, Engineering and Technology (FCCSET) and reports to the Office of Science and Technology Policy (OSTP), Executive Office of the President. Its overall charge is to coordinate radiation matters between agencies, evaluate radiation research, and provide advice on the formulation of radiation policy. During CIRRPC's second year, the member agencies have called upon this interagency resource to assist in coordinating science and policy issues and to provide a vehicle to accomplish multiagency tasks

  10. ITER co-ordinated technical activities

    International Nuclear Information System (INIS)

    2001-01-01

    As agreed upon between the ITER Engineering Design Activities (EDA) Parties 'Co-ordinated Technical Activities' (CTA) means technical activities which are deemed necessary to maintain the integrity of the international project, so as to prepare for the ITER joint implementation. The scope of these activities includes design adaptation to the specific site conditions, safety analysis and licensing preparation that are based on specific site offers, evaluation of cost and construction schedule, preparation of procurement documents and other issues raised by the Parties collectively, whilst assuring the coherence of the ITER project including design control

  11. Asian Network for Education in Nuclear Technology (ANENT). Report of the 1. Coordination Committee meeting including the ANENT Terms of Reference and the Action Plan

    International Nuclear Information System (INIS)

    2007-01-01

    It was noted that ANENT activities have started and ANENT is operational. The following conclusions are made: 1. Member States representatives are encouraged to contact IAEA TC through their respective official channels to request support for ANENT as a Regional TC Project; 2. Member States are invited to consider hosting one of the next Coordination Committee meetings; 3. The further ANENT activities should take into account the fact that nuclear energy and nuclear applications play equally important roles in Asia; 4. Nuclear safety plays a very important role and is being addressed through the ANSN. The meeting encouraged that ANSN and ANENT work together for synergistic effects. It was agreed that a representative from MINT would take the role of spokesperson of ANENT until the next Coordination Committee meeting

  12. Energy Materials Coordinating Committee (EMaCC), fiscal year 1985. Annual technical report

    International Nuclear Information System (INIS)

    1986-05-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meeting/workshops on selected topics involving both DOE and major contractors. Four topical subcommittees on Structural Ceramics, Batteries and Fuel Cells, Radioactive Waste Containment, and Steel are established and are continuing their own program. The FY 1985 and FY 1986 meeting program is given. The EMaCC aids in obtaining materials-related inputs for both intra- and inter-agency compilations. Brief summaries of the materials research programs associated with each office and division are presented, including tables listing individual projects and the FY 1985 budgets for each. More details on the individual projects within the divisions and the specific tasks or subcontracts within the various projects are given in the paragraph descriptions

  13. Energy Materials Coordinating Committee (EMaCC), fiscal year 1985. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1986-05-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meeting/workshops on selected topics involving both DOE and major contractors. Four topical subcommittees on Structural Ceramics, Batteries and Fuel Cells, Radioactive Waste Containment, and Steel are established and are continuing their own program. The FY 1985 and FY 1986 meeting program is given. The EMaCC aids in obtaining materials-related inputs for both intra- and inter-agency compilations. Brief summaries of the materials research programs associated with each office and division are presented, including tables listing individual projects and the FY 1985 budgets for each. More details on the individual projects within the divisions and the specific tasks or subcontracts within the various projects are given in the paragraph descriptions.

  14. Joint Coordinating Committee on environmental restoration and waste management (JCCEM) support, technology transfer, and special projects

    International Nuclear Information System (INIS)

    Edgar, D.E.

    1993-01-01

    Argonne National Laboratory (ANL) assisted in identifying and evaluating foreign technologies to meet EM needs; supported the evaluation, removal, and/or revision of barriers to international technology and information transfer/exchange; facilitated the integration and coordination of U.S. government international environmental restoration and waste management activities; and enhanced U.S. industry's competitiveness in the international environmental technology market

  15. 78 FR 63494 - Meeting of the National Coordination Committee on the AI/AN SANE-SART Initiative

    Science.gov (United States)

    2013-10-24

    ... National Coordination Committee on the AI/AN SANE--SART Initiative AGENCY: Office for Victims of Crime.../ Alaska Native (AI/AN) Sexual Assault Nurse Examiner (SANE)--Sexual Assault Response Team (SART..., victim-centered responses to sexual violence within AI/AN communities. DATES: The meeting will be held...

  16. Working Group 7.1 on environmental transport, US-USSR Joint Coordinating Committee on Civilian Nuclear Reactor Safety

    International Nuclear Information System (INIS)

    Anspaugh, L.R.; Hendrickson, S.M.

    1991-01-01

    This report contains brief summaries of the status of projects of the Environmental Transport Group of the US-USSR Joint Coordinating Committee of Civilian Nuclear Reactor Safety. Projects reported on include: Management and Administration; Atmospheric Transport; Resuspension; External Dose; Terrestrial Food Chains; Aquatic Food Chains; Hydrological Transport; and Intercalibration

  17. 76 FR 4352 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2011-01-25

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Policy Committee's Workgroups: Meaningful Use, Privacy & Security Tiger..., implementation specifications, and certification criteria are needed. Date and Time: The HIT Policy Committee...

  18. 75 FR 3906 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-01-25

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Policy Committee's Workgroups: Meaningful Use, Privacy & Security Policy... specifications, and certification criteria are needed. Date and Time: The HIT Policy Committee Workgroups will...

  19. 75 FR 65636 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-10-26

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  20. 75 FR 57027 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-09-17

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  1. 75 FR 62399 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-10-08

    ... Technology; HIT Standards Committee Schedule for the Assessment of HIT Policy Committee Recommendations.... SUMMARY: Section 3003(b)(3) of the American Recovery and Reinvestment Act of 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy recommendations developed by the HIT...

  2. 75 FR 42090 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-07-20

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  3. International Project Management Committee: Overview and Activities

    Science.gov (United States)

    Hoffman, Edward

    2010-01-01

    This slide presentation discusses the purpose and composition of the International Project Management Committee (IMPC). The IMPC was established by members of 15 space agencies, companies and professional organizations. The goal of the committee is to establish a means to share experiences and best practices with space project/program management practitioners at the global level. The space agencies that are involved are: AEB, DLR, ESA, ISRO, JAXA, KARI, and NASA. The industrial and professional organizational members are Comau, COSPAR, PMI, and Thales Alenia Space.

  4. Co-ordinating Product Developing Activities

    DEFF Research Database (Denmark)

    Terkelsen, Søren Bendix

    1996-01-01

    The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature......The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature...

  5. Co-ordination of satellite and data programs: The committee on earth observation satellites' approach

    Science.gov (United States)

    Embleton, B. J. J.; Kingwell, J.

    1997-01-01

    Every year, an average of eight new civilian remote sensing satellite missions are launched. Cumulatively, over 250 such missions, each with a cost equivalent in current value to between US 100 million to US 1000 million, have been sponsored by space agencies in perhaps two dozen countries. These missions produce data and information products which are vital for informed decision making all over the world, on matters relating to natural resource exploitation, health and safety, sustainable national development, infrastructure planning, and a host of other applications. By contributing to better scientific understanding of global changes in the atmosphere, land surface, oceans and ice caps, these silently orbiting sentinels in the sky make it possible for governments and industries to make wiser environmental policy decisions and support the economic development needs of humanity. The international Committee on Earth Observation Satellites (CEOS) is the premier world body for co-ordinating and planning civilian satellite missions for Earth observation. Through its technical working groups and special task teams, it endeavours to: • maximise the international benefits from Earth observation satellites; and • harmonise practice in calibration, validation, data management and information systems for Earth observation. CEOS encompasses not only space agencies (data providers), but also the great international scientific and operational programs which rely on Earth science data from space. The user organisations affiliated with CEOS, together with the mission operators, attempt to reconcile user needs with the complex set of considerations — including national interests, cost, schedule — which affect the undertaking of space missions. Without such an internationally co-ordinated consensual approach, there is a much greater risk of waste through duplication, and of missed opportunity, or through the absence of measurements of some vital physical or biological

  6. Stellarator Research Opportunities: A report of the National Stellarator Coordinating Committee

    Energy Technology Data Exchange (ETDEWEB)

    Gates, David A. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Anderson, David [University of Wisconsin-Madison

    2017-06-01

    This document is the product of a stellarator community workshop, organized by the National Stellarator Coordinating Committee and referred to as Stellcon, that was held in Cambridge, Massachusetts in February 2016, hosted by MIT. The workshop was widely advertised, and was attended by 40 scientists from 12 different institutions including national labs, universities and private industry, as well as a representative from the Department of Energy. The final section of this document describes areas of community wide consensus that were developed as a result of the discussions held at that workshop. Areas where further study would be helpful to generate a consensus path forward for the US stellarator program are also discussed. The program outlined in this document is directly responsive to many of the strategic priorities of FES as articulated in “Fusion Energy Sciences: A Ten-Year Perspective (2015-2025)” [2]. The natural disruption immunity of the stellarator directly addresses “Elimination of transient events that can be deleterious to toroidal fusion plasma confinement devices” an area of critical importance for the U.S. fusion energy sciences enterprise over the next decade. Another critical area of research “Strengthening our partnerships with international research facilities,” is being significantly advanced on the W7-X stellarator in Germany and serves as a test-bed for development of successful international collaboration on ITER. This report also outlines how materials science as it relates to plasma and fusion sciences, another critical research area, can be carried out effectively in a stellarator. Additionally, significant advances along two of the Research Directions outlined in the report; “Burning Plasma Science: Foundations - Next-generation research capabilities”, and “Burning Plasma Science: Long pulse - Sustainment of Long-Pulse Plasma Equilibria” are proposed.

  7. Stellarator Research Opportunities: A Report of the National Stellarator Coordinating Committee

    Science.gov (United States)

    Gates, D. A.; Anderson, D.; Anderson, S.; Zarnstorff, M.; Spong, D. A.; Weitzner, H.; Neilson, G. H.; Ruzic, D.; Andruczyk, D.; Harris, J. H.; Mynick, H.; Hegna, C. C.; Schmitz, O.; Talmadge, J. N.; Curreli, D.; Maurer, D.; Boozer, A. H.; Knowlton, S.; Allain, J. P.; Ennis, D.; Wurden, G.; Reiman, A.; Lore, J. D.; Landreman, M.; Freidberg, J. P.; Hudson, S. R.; Porkolab, M.; Demers, D.; Terry, J.; Edlund, E.; Lazerson, S. A.; Pablant, N.; Fonck, R.; Volpe, F.; Canik, J.; Granetz, R.; Ware, A.; Hanson, J. D.; Kumar, S.; Deng, C.; Likin, K.; Cerfon, A.; Ram, A.; Hassam, A.; Prager, S.; Paz-Soldan, C.; Pueschel, M. J.; Joseph, I.; Glasser, A. H.

    2018-02-01

    This document is the product of a stellarator community workshop, organized by the National Stellarator Coordinating Committee and referred to as Stellcon, that was held in Cambridge, Massachusetts in February 2016, hosted by MIT. The workshop was widely advertised, and was attended by 40 scientists from 12 different institutions including national labs, universities and private industry, as well as a representative from the Department of Energy. The final section of this document describes areas of community wide consensus that were developed as a result of the discussions held at that workshop. Areas where further study would be helpful to generate a consensus path forward for the US stellarator program are also discussed. The program outlined in this document is directly responsive to many of the strategic priorities of FES as articulated in "Fusion Energy Sciences: A Ten-Year Perspective (2015-2025)" [1]. The natural disruption immunity of the stellarator directly addresses "Elimination of transient events that can be deleterious to toroidal fusion plasma confinement devices" an area of critical importance for the US fusion energy sciences enterprise over the next decade. Another critical area of research "Strengthening our partnerships with international research facilities," is being significantly advanced on the W7-X stellarator in Germany and serves as a test-bed for development of successful international collaboration on ITER. This report also outlines how materials science as it relates to plasma and fusion sciences, another critical research area, can be carried out effectively in a stellarator. Additionally, significant advances along two of the Research Directions outlined in the report; "Burning Plasma Science: Foundations - Next-generation research capabilities", and "Burning Plasma Science: Long pulse - Sustainment of Long-Pulse Plasma Equilibria" are proposed.

  8. Committees review activities at December meetings

    Science.gov (United States)

    The Education and Human Resources Committee reported having approved participation in the Association for Women Geoscientist's (AWG) national survey. During the summer of 1983 the AWG designed a 75-question survey targeted to women but also applicable to men. The survey consisted of five sections (in addition to such demographics as age, salary, education, job area, and society membership): feelings and attitude toward job, career/family balance, sexual harassment and discrimination, opinions on national energy and conservation policy, and attitude toward AWG. The questionnaire was mailed to AWG members (just over 1000) and to AGU female members (about 1300). Survey participants were asked to give copies to their male colleagues to create a comparison group. About 25% of the 800 responses were from men. The responses were split about 50/50 between AWG and AGU members. The Education and Human Resources Committee will have the results from the survey presented at their next meeting in Cincinnati, May 15.

  9. 23 CFR 450.208 - Coordination of planning process activities.

    Science.gov (United States)

    2010-04-01

    ... process. (h) The statewide transportation planning process should be consistent with the Strategic Highway... 23 Highways 1 2010-04-01 2010-04-01 false Coordination of planning process activities. 450.208... Coordination of planning process activities. (a) In carrying out the statewide transportation planning process...

  10. Promoting proteomics knowledge in Europe: report on the activities of the EuPA Education Committee 2006-2007

    DEFF Research Database (Denmark)

    Albar, Juan Pablo; Corthals, Garry L; Gil, Concha

    2007-01-01

    the last year the EuPA Education Committee has coordinated or supported different educational activities including basic and advanced courses, a summer school, workshops and tutorials. A new programme of basic courses dubbed "Teaching the Teachers" has been initiated. These courses reach a larger, Europe...

  11. Twenty-Third Report of the Administrative Committee on Co-ordination to the Economic and Social Council of the United Nations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1959-07-09

    In accordance with Article XI of the Relationship Agreement between the Agency and the United Nations, the Agency is participating in the work of the Administrative Committee on Co-ordination (ACC) and of certain of its subsidiary bodies.

  12. 75 FR 57276 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-09-20

    ...: Health IT Policy Committee's Governance Workgroup. General Function of the Health IT Policy Committee: To... use of health information as is consistent with the Federal Health IT Strategic Plan and that includes... needed. Purpose of the Governance Workgroup: To draft a set of recommendations on the scope and process...

  13. Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    This booklet summarizes the main activities being carried out by the IAEA with regard to the Asian Network for Education in Nuclear Technology (ANENT) and other related activities including those completed during the period 2002-2005. It briefly describes the background information on the events leading to the formation of the ANENT; the terms of reference formulated at the second Coordination Committee meeting held in Vietnam, October 2005; and objectives, strategy and other institutional and managerial policies reaffirmed by the members. The attached CD-ROM contains nearly all of the background material in full text, including policy level papers, reports, presentations made by Member States, and meeting summaries

  14. Committee on Interagency Radiation Research and Policy Coordination (CIRRPC). Seventh annual report

    International Nuclear Information System (INIS)

    Young, A.L.

    1991-01-01

    In 1990--91 CIRRPC's program included efforts to improve interagency coordination on ionizing radiation risk assessments, a review of the reported health risks to humans from exposure to extremely low- frequency electric and magnetic fields (ELF/EMF), and increased coordination with national and international organizations such as NCRP and ICRP

  15. Activities on covariance estimation in Japanese Nuclear Data Committee

    Energy Technology Data Exchange (ETDEWEB)

    Shibata, Keiichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    Described are activities on covariance estimation in the Japanese Nuclear Data Committee. Covariances are obtained from measurements by using the least-squares methods. A simultaneous evaluation was performed to deduce covariances of fission cross sections of U and Pu isotopes. A code system, KALMAN, is used to estimate covariances of nuclear model calculations from uncertainties in model parameters. (author)

  16. Report of activities of the Japanese Nuclear Data Committee

    International Nuclear Information System (INIS)

    1977-01-01

    A progress report of the Japanese Nuclear Data Committee for the period of April 1, 1975 to March 31, 1977 is presented with emphasis on the topics of Japanese Evaluated Nuclear Data Library, version I(JENDL-1). Activities of working groups are also reported briefly. (auth.)

  17. International coordination of activities for establishing protective measures for the case of accidental release of radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    The document discussed here has been submitted to the WHO Regional Committee as a basis for discussion on the international coordination of protective measures in case of large-area radioactive contamination. The document presents the following: a summary of actions taken by the regional office in response to the Chernobyl reactor accident, and of the national and international measures for public health protection after the accident; brief review of actions taken by other international organisations, and the activities proposed by the WHO on a European and on a global level. (orig./HSCH).

  18. Coordinating Management Activities in Distributed Software Development Projects

    OpenAIRE

    Bendeck, Fawsy; Goldmann, Sigrid; Holz, Harald; Kötting, Boris

    1999-01-01

    Coordinating distributed processes, especially engineering and software design processes, has been a research topic for some time now. Several approaches have been published that aim at coordinating large projects in general, and large software development processes in specific. However, most of these approaches focus on the technical part of the design process and omit management activities like planning and scheduling the project, or monitoring it during execution. In this paper, we focus o...

  19. IAEA CRP on Fission Yield Data and activity of WG in Japanese Nuclear Data Committee

    International Nuclear Information System (INIS)

    Katakura, Junichi; Fukahori, Tokio

    1999-01-01

    The outline of the coordinate research program on fission yield data organized by International Atomic Energy Agency and the working group on the subject newly organized in Japanese Nuclear Data Committee are presented. (author)

  20. 76 FR 9782 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2011-02-22

    ... Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces... for Health Information Technology (ONC). The meetings will be open to the public via dial-in access... policy framework for the development and adoption of a nationwide health information technology...

  1. Let the experts decide? Asymmetric information, abstention, and coordination in standing committees

    DEFF Research Database (Denmark)

    Morton, Rebecca B.; Tyran, Jean-Robert

    2011-01-01

    the asymmetry in information quality is large, we find that voting groups largely coordinate on the SVC equilibrium which is also Pareto optimal. However, we find that when the asymmetry in information quality is not large and the Pareto optimal equilibrium is for all to participate, significant numbers...

  2. Dose reconstruction for the Urals population. Joint Coordinating Committee on Radiation Effects Research, Project 1.1 -- Final report

    International Nuclear Information System (INIS)

    Degteva, M.O.; Drozhko, E.; Anspaugh, L.R.; Napier, B.A.; Bouville, A.C.; Miller, C.W.

    1996-02-01

    This work is being carried out as a feasibility study to determine if a long-term course of work can be implemented to assess the long-term risks of radiation exposure delivered at low to moderate dose rates to the populations living in the vicinity of the Mayak Industrial Association (MIA). This work was authorized and conducted under the auspices of the US-Russian Joint Coordinating Committee on Radiation Effects Research (JCCRER) and its Executive Committee (EC). The MIA was the first Russian site for the production and separation of plutonium. This plant began operation in 1948, and during its early days there were technological failures that resulted in the release of large amounts of waste into the rather small Techa River. There were also gaseous releases of radioiodines and other radionuclides during the early days of operation. In addition, there was an accidental explosion in a waste storage tank in 1957 that resulted in a significant release. The Techa River Cohort has been studied for several years by scientists from the Urals Research Centre for Radiation Medicine and an increase in both leukemia and solid tumors has been noted

  3. Dose reconstruction for the Urals population. Joint Coordinating Committee on Radiation Effects Research, Project 1.1 -- Final report

    Energy Technology Data Exchange (ETDEWEB)

    Degteva, M.O. [Urals Research Center for Radiation Medicine, Chelyabinsk (Russian Federation); Drozhko, E. [Branch 1 of Moscow Biophysics Inst., Ozersk (Russian Federation); Anspaugh, L.R. [Lawrence Livermore National Lab., CA (United States); Napier, B.A. [Pacific Northwest National Lab., Richland, WA (United States); Bouville, A.C. [National Cancer Inst., Bethesda, MD (United States); Miller, C.W. [Centers for Disease Control and Prevention, Atlanta, GA (United States)

    1996-02-01

    This work is being carried out as a feasibility study to determine if a long-term course of work can be implemented to assess the long-term risks of radiation exposure delivered at low to moderate dose rates to the populations living in the vicinity of the Mayak Industrial Association (MIA). This work was authorized and conducted under the auspices of the US-Russian Joint Coordinating Committee on Radiation Effects Research (JCCRER) and its Executive Committee (EC). The MIA was the first Russian site for the production and separation of plutonium. This plant began operation in 1948, and during its early days there were technological failures that resulted in the release of large amounts of waste into the rather small Techa River. There were also gaseous releases of radioiodines and other radionuclides during the early days of operation. In addition, there was an accidental explosion in a waste storage tank in 1957 that resulted in a significant release. The Techa River Cohort has been studied for several years by scientists from the Urals Research Centre for Radiation Medicine and an increase in both leukemia and solid tumors has been noted.

  4. Energy Materials Coordinating Committee (EMaCC), Fiscal year 1992. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The DOE EMaCC serves to coordinate the department`s materials programs and to further effective use of materials expertise within the department. This document presents summaries of budgets and of research projects, arranged according to the offices of energy efficiency and renewable energy, energy research, environmental restoration and waste management, nuclear energy, civilian radioactive waste management, defense, and fossil energy. A directory and a keyword index are included.

  5. Coordinated research activities: Annual report and statistics for 2004

    International Nuclear Information System (INIS)

    2005-05-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's coordinated research activities

  6. Coordinated research activities: Annual report and statistics for 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's coordinated research activities

  7. Coordinating technology introduction and entrepreneurial activities in rural areas

    NARCIS (Netherlands)

    Fokkema, J.E.; Pennink, B.J.W.; Simatupang, T.M.

    2017-01-01

    © Copyright 2017 Inderscience Enterprises Ltd. The main purpose of this research is to investigate how technology introduction projects in rural areas should be coordinated in order to achieve local economic development and the role of social capital and entrepreneurial activities. Characteristics

  8. Coordinated research activities: Annual report and statistics for 2005

    International Nuclear Information System (INIS)

    2006-06-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's Coordinated Research Activities contained

  9. Coordinated research activities: Annual report and statistics for 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The Agency's Coordinated Research Activities stimulate and coordinate the undertaking of research in selected nuclear fields by scientists in IAEA Member States. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These Coordinated Research Activities are normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual research contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports Doctoral CRPs, which are designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs currently implemented by the Human Health programme address the management of liver cancer using radionuclide methods, improvement of radiotherapy outcomes in AIDS cancer patients and isotopic and complementary tools for the study of micronutrient status and interactions in developing country populations exposed to multiple nutritional deficiencies. Further information on the Agency's Coordinated Research Activities contained

  10. Activities of the O&M committee history & future perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Poulis, D.S.

    1996-12-01

    This paper gives an overview of the Committee on Operation and Maintenance of Nuclear Power Plants, hereafter referred to as the O&M Committee, formed in June 1975 when the American National Standard Institute`s Committee on Reactor Plants and their Maintenance was disbanded. The O&M Committee`s history, structure, current focus and future perspectives will be presented. The purpose of this paper is to give information to industry and the public of the Committee`s on-going effort to make accurate and timely responses to the needs of the nuclear industry.

  11. Committees

    Science.gov (United States)

    2012-11-01

    Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro

  12. Coordinated research activities: Annual report and statistics for 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-15

    In 2007, a total of Euro 6 606 194 were obligated for the Agency's Coordinated Research Activities (Euro 6 515 957 from the regular budget and Euro 90 237 from extrabudgetary resources). Most of the Coordinated Research Activities are carried out via Coordinated Research Projects (CRPs) which bring together research institutes in both developing and developed Member States to collaborate on research topics of common interest. At the end of 2007, work was being carried out on 115 CRPs, 37 in Major Programme 1 - Nuclear Power, Fuel Cycle and Nuclear Science, 71 in Major Programme 2 - Nuclear Techniques for Development and Environmental Protection, and 7 in Major Programme 3 - Nuclear Safety and Security. The total amount obligated for these activities in 2007 was 15% more than in 2006, largely due to the implementation of 28 new CRPs. At the end of 2007 work was being carried out under 976 contracts and 562 agreements with institutes in 110 Member States. 72% of the funds obligated for contracts in 2007 were in respect of institutions in developing countries, primarily in the areas of food and agriculture and human health. During 2007, 21% of the Chief Scientific Investigators participating in Agency CRPs were female researchers. Efforts will continue to increase the participation of women and younger researcher in the Coordinated Research Activities. The forty two completed CRPs evaluated in Appendix E resulted in 9 PhDs, one masters degree and in the publishing of about 800 articles and reports, scientific papers, proceedings of scientific conferences and contribution to international conferences, as well as 13 IAEA TECDOCs, and various scientific databases and websites. Detailed evaluation reports on the outputs, effectiveness, impact, recommended future action, and resulting publications of these completed CRPs are included in in Appendix E of this report. (author)

  13. Coordinated research activities: Annual report and statistics for 2007

    International Nuclear Information System (INIS)

    2008-07-01

    In 2007, a total of Euro 6 606 194 were obligated for the Agency's Coordinated Research Activities (Euro 6 515 957 from the regular budget and Euro 90 237 from extrabudgetary resources). Most of the Coordinated Research Activities are carried out via Coordinated Research Projects (CRPs) which bring together research institutes in both developing and developed Member States to collaborate on research topics of common interest. At the end of 2007, work was being carried out on 115 CRPs, 37 in Major Programme 1 - Nuclear Power, Fuel Cycle and Nuclear Science, 71 in Major Programme 2 - Nuclear Techniques for Development and Environmental Protection, and 7 in Major Programme 3 - Nuclear Safety and Security. The total amount obligated for these activities in 2007 was 15% more than in 2006, largely due to the implementation of 28 new CRPs. At the end of 2007 work was being carried out under 976 contracts and 562 agreements with institutes in 110 Member States. 72% of the funds obligated for contracts in 2007 were in respect of institutions in developing countries, primarily in the areas of food and agriculture and human health. During 2007, 21% of the Chief Scientific Investigators participating in Agency CRPs were female researchers. Efforts will continue to increase the participation of women and younger researcher in the Coordinated Research Activities. The forty two completed CRPs evaluated in Appendix E resulted in 9 PhDs, one masters degree and in the publishing of about 800 articles and reports, scientific papers, proceedings of scientific conferences and contribution to international conferences, as well as 13 IAEA TECDOCs, and various scientific databases and websites. Detailed evaluation reports on the outputs, effectiveness, impact, recommended future action, and resulting publications of these completed CRPs are included in in Appendix E of this report. (author)

  14. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1996-12-01

    The FY 1995 budget summary table for DOE Materials Activities is presented on pages 6-8. Following the budget summary table is a set of detailed program descriptions for the FY 1995 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department A mission statement a budget summary table listing the project titles and FY 1995 funding, and detailed project summaries are presented for each Assistant Secretary office and the Office of Energy Research. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project as appropriate.

  15. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 1998

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1999-07-31

    The FY 1998 budget summary for DOE Materials Activities is presented on pages 7 and 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 9. Following the budget summary is a set of detailed program descriptions for the FY 1998 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 1998 funding, and detailed project summaries are presented for each Assistant Secretary office and the Office of Energy Research. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  16. Report of the solar astronomy task force to the ad hoc interagency coordinating committee on astronomy. Final report

    International Nuclear Information System (INIS)

    1975-06-01

    The report surveys United States solar astronomy activities, compiling agency program objectives and mission requirements, identifying activities in support of the program, and assessing money and manpower expenditures. The scope of solar astrophysics is defined, and the present state of knowledge is outlined. Federally supported solar research is described in detail, by major institution and by program category. The report also discusses a coordinated national program of solar astrophysics in terms of objectives and resources and the particular importance of the Sacramento Peak Observatory and the Solar Maximum Mission to this national program

  17. Energy Materials Coordinating Committee (EMaCC): Fiscal year 1986, Annual technical report

    International Nuclear Information System (INIS)

    1987-05-01

    The first part of the Program Descriptions consists of a funding summary for each Assistant Secretary office and the Office of Energy Research. This is followed by a summary of project titles and objectives, including the program/project manager(s) and principal investigator. The second part of the Program Descriptions consists of more detailed project summaries with project goals and accomplishments. They are for the Offices of Conservation and Renewable Energy, Energy Research, Nuclear Energy, Civilian Radioactive Waste Management, and Fossil Energy. Each of these are numbered for purposes of reference in the Keyword Index. The FY 1986 Budget Summary for materials activities in each of the 29 programs within the DOE are also included

  18. Hydrogen Energy Coordinating Committee annual report: Summary of DOE hydrogen programs for FY 1988

    International Nuclear Information System (INIS)

    1989-01-01

    The FY 1988 Summary is the eleventh consecutive yearly report providing an overview of the hydrogen-related programs of the DOE offices represented on the HECC. A historical summary of the hydrogen budgets of these offices is given. The distribution by mission-related program element for FY 1988, and the non-mission-related activities are given. Total DOE funding in FY 1988 for mission-related hydrogen research was $5.2 million; DOE non-mission-related hydrogen research funding totaled $30.0 million. The individual program elements are described in the body of this report, and more specific program information is given in the Technology Summary Forms in Appendix A. 2 tabs

  19. Coordinating complex decision support activities across distributed applications

    Science.gov (United States)

    Adler, Richard M.

    1994-01-01

    Knowledge-based technologies have been applied successfully to automate planning and scheduling in many problem domains. Automation of decision support can be increased further by integrating task-specific applications with supporting database systems, and by coordinating interactions between such tools to facilitate collaborative activities. Unfortunately, the technical obstacles that must be overcome to achieve this vision of transparent, cooperative problem-solving are daunting. Intelligent decision support tools are typically developed for standalone use, rely on incompatible, task-specific representational models and application programming interfaces (API's), and run on heterogeneous computing platforms. Getting such applications to interact freely calls for platform independent capabilities for distributed communication, as well as tools for mapping information across disparate representations. Symbiotics is developing a layered set of software tools (called NetWorks! for integrating and coordinating heterogeneous distributed applications. he top layer of tools consists of an extensible set of generic, programmable coordination services. Developers access these services via high-level API's to implement the desired interactions between distributed applications.

  20. Federal Interagency Committee on Indoor Air Quality

    Science.gov (United States)

    The Federal Interagency Committee on Indoor Air Quality (CIAQ), which meets three times a year, was established by Congress to coordinate the activities of the Federal Government on issues relating to Indoor Air Quality.

  1. Activities of the ANS special committee on nuclear nonproliferation

    Energy Technology Data Exchange (ETDEWEB)

    Buckner, M.R. [Westinghouse Savannah River Co., Aiken, SC (United States); Sanders, T.L. [Sandia National Labs., Albuquerque, NM (United States)

    2001-07-01

    The American Nuclear Society (ANS) Special Committee on Nuclear Nonproliferation (SCNN) believes that to reverse current trends, U.S. policy must revisit the fundamental premise of Atoms for Peace: A collaborative nuclear enterprise enhances rather than diminishes national security. To accomplish this, the U.S. Government must develop an integrated policy on energy, nuclear technology, and national security. The policy must recognize that these are interrelated and that an integrated policy will require substantial investments in nuclear research and development and in nuclear education. This paper describes the current activities of the SCNN to heighten awareness of nonproliferation issues for decision makers and ANS members, and alert them to the need for action to resolve these concerns. (author)

  2. Activities of the ANS special committee on nuclear nonproliferation

    International Nuclear Information System (INIS)

    Buckner, M.R.; Sanders, T.L.

    2001-01-01

    The American Nuclear Society (ANS) Special Committee on Nuclear Nonproliferation (SCNN) believes that to reverse current trends, U.S. policy must revisit the fundamental premise of Atoms for Peace: A collaborative nuclear enterprise enhances rather than diminishes national security. To accomplish this, the U.S. Government must develop an integrated policy on energy, nuclear technology, and national security. The policy must recognize that these are interrelated and that an integrated policy will require substantial investments in nuclear research and development and in nuclear education. This paper describes the current activities of the SCNN to heighten awareness of nonproliferation issues for decision makers and ANS members, and alert them to the need for action to resolve these concerns. (author)

  3. Report of the summative evaluation by the advisory committee on research support and collaborative activities

    International Nuclear Information System (INIS)

    2005-03-01

    The Research Evaluation Committee of the Japan Atomic Energy Research Institute (JAERI) set up an Advisory Committee on Research Support and Collaborative Activities in accordance with the 'Fundamental Guideline for the Evaluation of Research and Development (R and D) at JAERI' and its subsidiary regulations. The Advisory Committee on Research Support and Collaborative Activities evaluated the adequacy of the plans of research support and collaborative activities to be succeeded from JAERI to a new research institute which will be established by integration of JAERI and the Japan Nuclear Cycle Development Institute (JNC). The Advisory Committee consisted of nine specialists from outside the JAERI conducted its activities from June 2004 to August 2004. The evaluation was performed on the basis of the materials submitted in advance and of the oral presentations made at the Advisory Committee meeting which was held on July 21, 2004, in line with the items, viewpoints, and criteria for the evaluation specified by the Research Evaluation Committee. The result of the evaluation by the Advisory Committee was submitted to the Research Evaluation Committee, and was judged to be appropriate at its meeting held on December 1, 2004. This report describes the result of the evaluation by the Advisory Committee on Research Support and Collaborative Activities. (author)

  4. 75 FR 4904 - Railroad Safety Advisory Committee (RSAC); Working Group Activity Update

    Science.gov (United States)

    2010-01-29

    ... amend regulations protecting persons who work on, under, or between rolling equipment; and persons...-7257] Railroad Safety Advisory Committee (RSAC); Working Group Activity Update AGENCY: Federal Railroad... Committee (RSAC) Working Group Activities. SUMMARY: The FRA is updating its announcement of RSAC's Working...

  5. Bureau of Indian Affairs Advisory Committee for Exceptional Children. The Third Annual Report to the Department of the Interior.

    Science.gov (United States)

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC. Div. of Exceptional Education.

    The third annual report (1981-82) of the Bureau of Indian Affairs (BIA) Advisory Committee for Exceptional Children contains summaries of Committee meetings, results of a survey of BIA agency and area special education coordinators regarding Committee activities, recommendations, and five appendices. Results of the survey of coordinators indicate…

  6. Uranyl oxo activation and functionalization by metal cation coordination

    International Nuclear Information System (INIS)

    Arnold Polly, L.; Pecharman, A. F.; Hollis, E.; Parsons, S.; Love, J. B.; Yahia, A.; Maron, L.; Yahia, A.; Maron, L.

    2010-01-01

    The oxo groups in the uranyl ion [UO 2 ] 2+ - one of many oxo cations formed by metals from across the periodic table - are particularly inert, which explains the dominance of this ion in the laboratory and its persistence as an environmental contaminant. In contrast, transition metal oxo (M=O) compounds can be highly reactive and carry out difficult reactions such as the oxygenation of hydrocarbons. Here we show how the sequential addition of a lithium metal base to the uranyl ion constrained in a 'Pacman' environment results in lithium coordination to the U=O bonds and single-electron reduction. This reaction depends on the nature and stoichiometry of the lithium reagent and suggests that competing reduction and C-H bond activation reactions are occurring. (authors)

  7. Uranyl oxo activation and functionalization by metal cation coordination

    Energy Technology Data Exchange (ETDEWEB)

    Arnold Polly, L; Pecharman, A F; Hollis, E; Parsons, S; Love, J B [Univ Edinburgh, EaStCHEM Sch Chem, Edinburgh EH9 3JJ, Midlothian (United Kingdom); Yahia, A; Maron, L [Univ Toulouse 3, LPCNO, UMR 5215, INSA, CNRS, F-31077 Toulouse 4 (France); Yahia, A; Maron, L [Univ Montpellier 2, ENSCM, CNRS, ICSM, UMR 5257, CEA, Ctr Marcoule, F-30207 Bagnols Sur Ceze (France)

    2010-07-01

    The oxo groups in the uranyl ion [UO{sub 2}]{sup 2+} - one of many oxo cations formed by metals from across the periodic table - are particularly inert, which explains the dominance of this ion in the laboratory and its persistence as an environmental contaminant. In contrast, transition metal oxo (M=O) compounds can be highly reactive and carry out difficult reactions such as the oxygenation of hydrocarbons. Here we show how the sequential addition of a lithium metal base to the uranyl ion constrained in a 'Pacman' environment results in lithium coordination to the U=O bonds and single-electron reduction. This reaction depends on the nature and stoichiometry of the lithium reagent and suggests that competing reduction and C-H bond activation reactions are occurring. (authors)

  8. Cytosolic Calcium Coordinates Mitochondrial Energy Metabolism with Presynaptic Activity

    Science.gov (United States)

    Chouhan, Amit K.; Ivannikov, Maxim V.; Lu, Zhongmin; Sugimori, Mutsuyuki; Llinas, Rodolfo R.; Macleod, Gregory T.

    2012-01-01

    Most neurons fire in bursts, imposing episodic energy demands, but how these demands are coordinated with oxidative phosphorylation is still unknown. Here, using fluorescence imaging techniques on presynaptic termini of Drosophila motor neurons (MNs), we show that mitochondrial matrix pH (pHm), inner membrane potential (Δψm), and NAD(P)H levels ([NAD(P)H]m) increase within seconds of nerve stimulation. The elevations of pHm, Δψm, and [NAD(P)H]m indicate an increased capacity for ATP production. Elevations in pHm were blocked by manipulations which blocked mitochondrial Ca2+ uptake, including replacement of extracellular Ca2+ with Sr2+, and application of either tetraphenylphosphonium chloride or KB-R7943, indicating that it is Ca2+ that stimulates presynaptic mitochondrial energy metabolism. To place this phenomenon within the context of endogenous neuronal activity, the firing rates of a number of individually identified MNs were determined during fictive locomotion. Surprisingly, although endogenous firing rates are significantly different, there was little difference in presynaptic cytosolic Ca2+ levels ([Ca2+]c) between MNs when each fires at its endogenous rate. The average [Ca2+]c level (329±11nM) was slightly above the average Ca2+ affinity of the mitochondria (281±13nM). In summary, we show that when MNs fire at endogenous rates [Ca2+]c is driven into a range where mitochondria rapidly acquire Ca2+. As we also show that Ca2+ stimulates presynaptic mitochondrial energy metabolism, we conclude that [Ca2+]c levels play an integral role in coordinating mitochondrial energy metabolism with presynaptic activity in Drosophila MNs. PMID:22279208

  9. Final Progress Report for the activity called AMO2010 committee

    Energy Technology Data Exchange (ETDEWEB)

    Donald Shapero; Michael Moloney

    2006-12-31

    The committee was charged to produce a comprehensive report on the status of AMO Science. The committee was charged to produce a report that: 1. Reviewed the field of AMO science, emphasize recent accomplishments, and identify new opportunities and compelling scientific questions; 2. Identified the impact of AMO science on other scientific fields, emerging technologies, and national needs; 3. Identified future workforce, societal and educational needs for AMO science; and 4. Made recommendations on how the US research enterprise might realize the full potential of AMO science. The committee also produced an intermediate report addressing key research issues and themes facing the research community.

  10. High Committee for transparency and information on nuclear safety: Annual activity report (January 2010 - December 2010)

    International Nuclear Information System (INIS)

    2010-01-01

    After a description of the operation of the French 'High Committee for transparency and information on nuclear safety' (HCTISN), of its missions, its organisation and its means, the progress report presents the High Committee activity for 2010 with summaries of its report on the transparency of nuclear material and waste management, its meetings, its work groups, its visits and participations to other events

  11. Tips for Starting Physical Activity

    Science.gov (United States)

    ... Legislative Information Advisory & Coordinating Committees Strategic Plans & Reports Research Areas FAQs ... Starting Physical Activity Related Topics Section Navigation Tips to Help You Get Active ...

  12. HCTISN - High Committee for transparency and information on nuclear safety - Annual activity report - 2011

    International Nuclear Information System (INIS)

    2012-01-01

    This activity report first describes the Committee operation (missions, composition, organization and operation rules, and means). Then, it reports the Committee's activity during 2011: works related to the Fukushima accident, report and recommendations on transparency and secrets in the nuclear sector, report and recommendations on the search for a storage site for long life and low activity wastes, meetings and work-groups, and visits

  13. Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma.

    Science.gov (United States)

    Yahagi, Naoya; Shimano, Hitoshi; Hasegawa, Kiyoshi; Ohashi, Kenichi; Matsuzaka, Takashi; Najima, Yuho; Sekiya, Motohiro; Tomita, Sachiko; Okazaki, Hiroaki; Tamura, Yoshiaki; Iizuka, Yoko; Ohashi, Ken; Nagai, Ryozo; Ishibashi, Shun; Kadowaki, Takashi; Makuuchi, Masatoshi; Ohnishi, Shin; Osuga, Jun-ichi; Yamada, Nobuhiro

    2005-06-01

    Hepatocellular carcinoma is a very common neoplastic disease in countries where hepatitis viruses B and/or C are prevalent. Small hepatocellular carcinoma lesions detected by ultrasonography at an early stage are often hyperechoic because they are composed of well-differentiated cancer cells that are rich in triglyceride droplets. The triglyceride content of hepatocytes depends in part on the rate of lipogenesis. Key lipogenic enzymes, such as fatty acid synthase, are co-ordinately regulated at the transcriptional level. We therefore examined the mRNA expression of lipogenic enzymes in human hepatocellular carcinoma samples from 10 patients who had undergone surgical resection. All of the samples exhibited marked elevation of expression of mRNA for lipogenic enzymes, such as fatty acid synthase, acetyl-CoA carboxylase and ATP citrate lyase, compared with surrounding non-cancerous liver tissue. In contrast, the changes in mRNA expression of SREBP-1, a transcription factor that regulates a battery of lipogenic enzymes, did not show a consistent trend. In some cases where SREBP-1 was elevated, the main contributing isoform was SREBP-1c rather than SREBP-1a. Thus, lipogenic enzymes are markedly induced in hepatocellular carcinomas, and in some cases SREBP-1c is involved in this activation.

  14. Photocatalytic activity of PANI loaded coordination polymer composite materials: Photoresponse region extension and quantum yields enhancement via the loading of PANI nanofibers on surface of coordination polymer

    International Nuclear Information System (INIS)

    Cui, Zhongping; Qi, Ji; Xu, Xinxin; Liu, Lu; Wang, Yi

    2013-01-01

    To enhance photocatalytic property of coordination polymer in visible light region, polyaniline (PANI) loaded coordination polymer photocatalyst was synthesized through in-situ chemical oxidation of aniline on the surface of coordination polymer. The photocatalytic activity of PANI loaded coordination polymer composite material for degradation of Rhodamine B (RhB) was investigated. Compared with pure coordination polymer photocatalyst, which can decompose RhB merely under UV light irradiation, PANI loaded coordination polymer photocatalyst displays more excellent photocatalytic activity in visible light region. Furthermore, PANI loaded coordination polymer photocatalyst exhibits outstanding stability during the degradation of RhB. - Graphical abstract: PANI loaded coordination polymer composite material, which displays excellent photocatalytic activity under visible light was firstly synthesized through in-situ chemical oxidation of aniline on surface of coordination polymer. Display Omitted - Highlights: • This PANI loaded coordination polymer composite material represents the first conductive polymer loaded coordination polymer composite material. • PANI/coordination polymer composite material displays more excellent photocatalytic activity for the degradation of MO in visible light region. • The “combination” of coordination polymer and PANI will enable us to design high-activity, high-stability and visible light driven photocatalyst in the future

  15. Opinions expressed by Italian National Advisory Toxicological Committee on some active ingredients of pesticides

    Energy Technology Data Exchange (ETDEWEB)

    Camoni, I [Ist. Superiore di Sanita` , Rome (Italy). Lab. di Tossicologia Applicata

    1996-03-01

    The opinions expressed by the Italian National Advisory Toxicological Committee (CCTN) on some active ingredients of pesticides are presented. Carcinogenic and mutagenic effects of these substances have been examined and, on this basis, an evaluation and relative classification were expressed.

  16. Activities of the research committee on thorium cycle in atomic energy society of Japan

    International Nuclear Information System (INIS)

    Hohki, Shiro

    1985-01-01

    In 1978 the Research Committee on Thorium Cycle was established as one of committees of the Atomic Energy Society of Japan, and the Committee published a report titled 'The Thorium Cycle - Present Status and Future Prospect' in October 1980 as a result of investigations on the status of the thoirum cycle in Japan as well as that in overseas. Based on this investigation, the Committee is intending to evaluate synthetically the thorium utilization in Japan under the prospect for the middle and long term by intensifying the activities of the Committee. Furthermore, from this viewpoint, the author supplements comments on following three points: (1) Reasons why the thorium utilization has not received positive evaluation in Japan; (2) Reasons why Japan has to pay attention to thorium; (3) How the technology on thorium should be developed in Japan. (author)

  17. Effects of Man's Activities on the Marine Environment; Committee on Commerce, United States Senate, Ninety-Fourth Congress, First Session. Committee Print.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Committee on Commerce.

    This report, prepared for the Committee on Commerce and the National Ocean Policy Study Committee, describes many aspects of water pollution, both national and international. Specific sections are devoted to: (1) assessing man's influence on the oceans, (2) activities that generate marine pollution, (3) specific marine pollutants, (4) policy for…

  18. Coordination of physicians' operational activities : a Contingency perspective

    NARCIS (Netherlands)

    Broekhuis, Manda; van Donk, Dirk Pieter

    2011-01-01

    Purpose - The purpose of this paper is to investigate the impact of three different dimensions of customer-induced uncertainty and task uncertainty on the mix of physicians' coordination practices. Design/methodology/approach - An improvement and research project are combined resulting in 16 case

  19. Managing Nuclear Knowledge: IAEA Activities and International Coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    The important role which the International Atomic Energy Agency (IAEA) plays in assisting Member States in the preservation and enhancement of nuclear knowledge and in facilitating international collaboration in this area has been recognized by the General Conference of the International Atomic Energy Agency in resolutions GC(46)/RES/11B, GC(47)/RES/10B, GC(48)/RES/13 and GC(50)/RES/13. The IAEA continues to support the enhancement and stabilization of nuclear education and training with the objective of securing the availability of qualified human resources for the nuclear sector. Its most important approaches are networking regional educational institutions and fostering cooperation to develop harmonized curricula, prepare and disseminate teaching materials. The Asian Network for Education in Nuclear Technology (ANENT), established by the IAEA in 2004, became operational in 2005. An ANENT website has been set up and is being expanded, such as developing a long-distance learning platform. Also, a reference curriculum for nuclear engineering is being developed with the cooperation of external partners.This booklet summarizes the main activities being carried out by the IAEA with regard to the Asian Network for Education in Nuclear Technology (ANENT) and other related activities including those completed during the period 2002–2005. It briefly describes the background information on the events leading to the formation of the ANENT; the terms of reference formulated at the second Coordination Committee meeting held in Vietnam, October 2005; and objectives, strategy and other institutional and managerial policies reaffirmed by the members. CD-ROM attached to the printed booklet containing nearly all of the background material in full text, including policy level papers, reports, presentations made by Member States, and meeting summaries

  20. On the activities and perspective works of Soviet Scientist Committee for peace against nuclear hazard

    International Nuclear Information System (INIS)

    Velikhov, E.P.

    1986-01-01

    Activities of Soviet Scientists' Committee for peace against nuclear hazard established in May 1983 was considered. Committee efforts are directed at struggle for nuclear weapon destruction, for stopping of all kinds of its tests against disposition of nuclear waepon in space. Soviet scientist report on SDI says that such system may serve not only as defensive means but also as means of destruction of earth, air and other objects and represents the most serious danger. Together with american scientists the Committee investigated ecological consequencies of nuclear war which results strongly impressed all over the world. Attention is paid to prospects in the Committee work related to the development of nuclear weapon destribution procedures as well as procedures and means of controls for destruction and limitation of weapons

  1. Activity report of Japanese Nuclear Data Committee in period of April 1997 to March 1999

    International Nuclear Information System (INIS)

    1999-01-01

    This report presents the activities of the Japanese Nuclear Data Committee (JNDC) in the period of April 1997 to March 1999. In this period, preparation of the next version of the Japanese Evaluated Nuclear Data Library, JENDL-3.3, has progressed. Generation of the special purpose files also has been advanced. In this report, the activities of each group affiliated by the committee are presented and the following are described as special topics : (1) progress in evaluating JENDL-3.3, (2) production of JENDL Covariance File and its processing system, (3) completion of the JENDL Dosimetry File, and (4) the JENDL FP Decay Data File. (author)

  2. Iron Coordination and Halogen-Bonding Assisted Iodosylbenzene Activation

    DEFF Research Database (Denmark)

    Wegeberg, Christina; Poulsen de Sousa, David; McKenzie, Christine

    catalytic mixtures using soluble terminal oxygen transfer agents. Isolation of a reactive iron-terminal oxidant adduct, an unique Fe(III)-OIPh complex, is facilitated by strong stabilizing supramolecular halogen-bonding. L3-edge XANES suggests +1.6 for the average oxidation state for the iodine atom3......The iron complex of the hexadentate ligand N,N,N'-tris(2-pyridylmethyl)ethylendiamine-N'-acetate (tpena) efficiently catalyzes selective oxidations of electron-rich olefins and sulfides by insoluble iodosylbenzene (PhIO). Surprisingly, these reactions are faster and more selective than homogenous...... in the iron(III)-coordinated PhIO. This represents a reduction of iodine relative to the original “hypervalent” (+3) PhIO. The equivalent of electron density must be removed from the {(tpena)Fe(III)O} moiety, however Mössbauer spectroscopy shows that the iron atom is not high valent....

  3. Relationships between physical activity, physical fitness, somatic fitness, and coordination along childhood and adolescence

    Directory of Open Access Journals (Sweden)

    João Paulo Saraiva

    2010-12-01

    Full Text Available The two main goals of this review were to understand how the relationships between physical activity, physical fitness, somatic fitness, and coordination are established along the motor development of children and adolescents, and how they would influence their future lives. The web based bibliographic database B-On was searched for peer-reviewed publications during the last decade (2000 to 2009. Search criteria included all articles on relationships between any two of the above named factors. Although different methodological designs and variables were found as markers for the same factor, overall results suggested the existence of a clear positive relationship among physical activity, physical fitness, somatic fitness, and coordination from childhood to adolescence, with a special relevance for the relationship between physical activity and coordination. It was also noted a renewed interest on physical activity and motor coordination developmental characteristics and relationships as well as on their lifelong health effects.

  4. Relationships between physical activity, physical fitness, somatic fitness, and coordination along childhood and adolescence

    Directory of Open Access Journals (Sweden)

    J.P. Saraiva

    2010-01-01

    Full Text Available The two main goals of this review were to understand how the relationships between physical activity, physical fitness, somatic fitness, and coordination are established along the motor development of children and adolescents, and how they would influence their future lives. The web based bibliographic database B-On was searched for peer-reviewed publications during the last decade (2000 to 2009. Search criteria included all articles on relationships between any two of the above named factors. Although different methodological designs and variables were found as markers for the same factor, overall results suggested the existence of a clear positive relationship among physical activity, physical fitness, somatic fitness, and coordination from childhood to adolescence, with a special relevance for the relationship between physical activity and coordination. It was also noted a renewed interest on physical activity and motor coordination developmental characteristics and relationships as well as on their lifelong health effects.

  5. Activities of Daily Living in Children With Developmental Coordination Disorder : Performance, Learning, and Participation

    NARCIS (Netherlands)

    Van der Linde, Berdien W.; van Netten, Jaap J.; Otten, Bert; Postema, Klaas; Geuze, Reint H.; Schoemaker, Marina M.

    2015-01-01

    Background. Children with developmental coordination disorder (DCD) face evident motor difficulties in daily functioning. Little is known, however, about their difficulties in specific activities of daily living (ADL). Objective. The purposes of this study were: (1) to investigate differences

  6. Activities of daily living in children with developmental coordination disorder : performance, learning, and participation

    NARCIS (Netherlands)

    Moraal-van der Linde, Berdien; Netten, Jaap; Otten, Bert; Postema, Klaas; Geuze, Reint; Schoemaker, Marina

    2015-01-01

    Background. Children with developmental coordination disorder (DCD) face evident motor difficulties in daily functioning. Little is known, however, about their difficulties in specific activities of daily living (ADL). Objective. To (a) investigate differences between children with DCD and their

  7. Initial activities of the ITER Management Advisory Committee

    International Nuclear Information System (INIS)

    Yoshikawa, Masaji

    1994-01-01

    The first ITER Council meeting (IC-1) took place in Vienna Austria at the International Atomic Energy Agency (IAEA) headquarters on 10-11 September, 1992. At that meeting the Council appointed Dr. Masaji Yoshikawa as Chair of the Management Advisory Committee (MAC). The Parties designated the members of MAC. The first MAC meeting was held at the ITER CoCenter, Naka, Japan, on 1-3 December 1992 and reviewed its tasks as charged by the Council. In accordance with Article 7 of the ITER EDA Agreement, it is the responsibility of MAC to report to and advise the ITER Council in management and administrative matters, including finance, personnel and task assignment. Also, in accordance with Article 11 of the ITER EDA Agreement, the MAC advises the ITER Council on the Work Program developed by the Director. The Work Program is to contain a detailed list of specific tasks, including a technical description of each task, and the assignment of the specific tasks to each of the Home Teams and the Joint Central Team (JCT), and a flow chart of the specific tasks during the whole EDA. According to Section 3 of Protocol 1, the tasks are to be performed by the Home Teams; task descriptions are to contain a detailed technical description of each task and an indication of the facilities and background information needed for its implementation

  8. Beyond Therapy Dogs: Coordinating Large-Scale Finals Week Activities

    Science.gov (United States)

    Flynn, Holly

    2017-01-01

    Finals week activities have become increasingly popular in academic libraries in the last few years, but what is a library to do when it is not allowed to have therapy dogs? This column examines a progression of increasingly popular activities at Michigan State University Libraries. Included is an assessment of what makes them popular, our…

  9. 75 FR 51525 - Railroad Safety Advisory Committee (RSAC); Working Group Activity Update

    Science.gov (United States)

    2010-08-20

    .... The Working Group continues to work on after arrival orders, and at the September 25-26, 2008, meeting... protecting persons who work on, under, or between rolling equipment and persons applying, removing or.... 63] Railroad Safety Advisory Committee (RSAC); Working Group Activity Update AGENCY: Federal Railroad...

  10. Activity report of Japanese Nuclear Data Committee in the period of April 1977 -- March 1979

    International Nuclear Information System (INIS)

    1979-01-01

    This is a progress report of Japanese Nuclear Data Committee, covering the activities during the period of April 1977 -- March 1979. As special topics, the results of integral tests of Japanese Evaluated Nuclear Data Library, version 1 and the program for version 2 evaluation are described. (author)

  11. Coordinated research activities: Annual report and statistics for 2006

    International Nuclear Information System (INIS)

    2007-07-01

    In 2006, a total of Euro 5 622 290 from the regular budget and Euro 130 715 of extra budgetary contributions were awarded in support of Coordinated Research Projects (CRPs). The CRPs were in Major Programme 1 - Nuclear Power, Fuel Cycle and Nuclear Science, in Major Programme 2 - Nuclear Techniques for Development and Environmental Protection, and in Major Programme 3 - Nuclear Safety and Security. Compared with 2005, the amount awarded represented 20% lower financial support because of completion of 39 CRPs, but with only 19 new start-ups CRPs. Over 70% of the funds awarded for contracts were made to institutions in developing countries primarily in the areas of nuclear power, nuclear science, waste management, food and agriculture, human health, water resources and isotope hydrology, and nuclear safety and security. In numerical terms, at the end of 2006 there were 1385 contracts and agreements awarded to institutes in 108 Member States. The total number of contracts includes 772 research contracts and 107 technical contracts. In addition, 506 research agreements were awarded. Notwithstanding the Secretariat's efforts to increase the numbers of female Chief Scientific Investigators participating in CRPs, the percentage remained at 20%. Efforts continue to increase this figure. The completed CRPs resulted in one PhD, 5 master's degrees and 5 other theses and dissertations, and in the publishing of about 769 articles and reports, scientific papers, proceedings of scientific conferences and contribution to international conferences as well as 11 IAEA TECDOCs, a new scientific database and one website. Detailed reports on the outputs, effectiveness, impact, recommended future action, and resulting publications are listed in Appendix E of this report

  12. High committee for nuclear safety transparency and information. Annual activity report. June 2008 - December 2009

    International Nuclear Information System (INIS)

    2010-01-01

    This document is the first activity report of the High committee for nuclear safety transparency and information (HCTISN), created on June 18, 2008. The HCTISN is a French authority of information, dialogue and debate about the risks linked with nuclear activities and about their impacts on public health, on the environment and on nuclear safety. The committee has the ability to express his opinion and recommendations about any question on the above topics and to propose any measure aiming at warranting or improving the transparency in the nuclear domain. This activity report offers a synthetic overview of the actions already undertaken: the plutonium imports from UK, the contamination incident at the Socatri facility (a Areva-Eurodif daughter company located at the Tricastin site), and the dismantling strategy of basic nuclear facilities. It presents the composition, organization, missions and means of the Committee, the different working groups and the follow-up of the different recommendations emitted so far by the Committee. (J.S.)

  13. Flexible coordination of stationary and mobile conversations with gaze: Resource allocation among multiple joint activities

    Directory of Open Access Journals (Sweden)

    Eric Mayor

    2016-10-01

    Full Text Available Gaze is instrumental in coordinating face-to-face social interactions. But little is known about gaze use when social interactions co-occur with other joint activities. We investigated the case of walking while talking. We assessed how gaze gets allocated among various targets in mobile conversations, whether allocation of gaze to other targets affects conversational coordination, and whether reduced availability of gaze for conversational coordination affects conversational performance and content. In an experimental study, pairs were videotaped in four conditions of mobility (standing still, talking while walking along a straight-line itinerary, talking while walking along a complex itinerary, or walking along a complex itinerary with no conversational task. Gaze to partners was substantially reduced in mobile conversations, but gaze was still used to coordinate conversation via displays of mutual orientation, and conversational performance and content was not different between stationary and mobile conditions. Results expand the phenomena of multitasking to joint activities.

  14. Framework for development of physician competencies in genomic medicine: report of the Competencies Working Group of the Inter-Society Coordinating Committee for Physician Education in Genomics.

    Science.gov (United States)

    Korf, Bruce R; Berry, Anna B; Limson, Melvin; Marian, Ali J; Murray, Michael F; O'Rourke, P Pearl; Passamani, Eugene R; Relling, Mary V; Tooker, John; Tsongalis, Gregory J; Rodriguez, Laura L

    2014-11-01

    Completion of the Human Genome Project, in conjunction with dramatic reductions in the cost of DNA sequencing and advances in translational research, is gradually ushering genomic discoveries and technologies into the practice of medicine. The rapid pace of these advances is opening up a gap between the knowledge available about the clinical relevance of genomic information and the ability of clinicians to include such information in their medical practices. This educational gap threatens to be rate limiting to the clinical adoption of genomics in medicine. Solutions will require not only a better understanding of the clinical implications of genetic discoveries but also training in genomics at all levels of professional development, including for individuals in formal training and others who long ago completed such training. The National Human Genome Research Institute has convened the Inter-Society Coordinating Committee for Physician Education in Genomics (ISCC) to develop and share best practices in the use of genomics in medicine. The ISCC has developed a framework for development of genomics practice competencies that may serve as a starting point for formulation of competencies for physicians in various medical disciplines.

  15. Dopamine D1 receptor activation maintains motor coordination and balance in rats.

    Science.gov (United States)

    Avila-Luna, Alberto; Gálvez-Rosas, Arturo; Durand-Rivera, Alfredo; Ramos-Languren, Laura-Elisa; Ríos, Camilo; Arias-Montaño, José-Antonio; Bueno-Nava, Antonio

    2018-02-01

    Dopamine (DA) modulates motor coordination, and its depletion, as in Parkinson's disease, produces motor impairment. The basal ganglia, cerebellum and cerebral cortex are interconnected, have functional roles in motor coordination, and possess dopamine D 1 receptors (D 1 Rs), which are expressed at a particularly high density in the basal ganglia. In this study, we examined whether the activation of D 1 Rs modulates motor coordination and balance in the rat using a beam-walking test that has previously been used to detect motor coordination deficits. The systemic administration of the D 1 R agonist SKF-38393 at 2, 3, or 4 mg/kg did not alter the beam-walking scores, but the subsequent administration of the D 1 R antagonist SCH-23390 at 1 mg/kg did produce deficits in motor coordination, which were reversed by the full agonist SKF-82958. The co-administration of SKF-38393 and SCH-23390 did not alter the beam-walking scores compared with the control group, but significantly prevented the increase in beam-walking scores induced by SCH-23390. The effect of the D 1 R agonist to prevent and reverse the effect of the D 1 R antagonist in beam-walking scores is an indicator that the function of D 1 Rs is necessary to maintain motor coordination and balance in rats. Our results support that D 1 Rs mediate the SCH-23390-induced deficit in motor coordination.

  16. Committee on Military Nutrition Research Activity Report 1986 - 1992.

    Science.gov (United States)

    1992-06-29

    and to delay gastric emptying. there may be an increased incidence of ’heartburn’ due to reflux esophagitis , which can be debilitating in some people...enteric infection or diarrhea, which could be aggravated by the high-fat ration. C. Since high-fat diets are known to lower esophag al sphincter pressure...with depressed NK activity (Levy et al., 1991 a,b). Gastro -intestinal infections have also caused problems in other Rangar Training classes. However, it

  17. Activities of HPS standards committee in environmental remediation

    International Nuclear Information System (INIS)

    Stencel, J.R.

    1994-01-01

    The Health Physics Society (HPS) develops American National Standards in the area of radiation protection using methods approved by the American National Standards Institute (ANSI). Two of its sections, Environmental Health Physics and Contamination Limits, have ongoing standards development which are important to some environmental remediation efforts. This paper describes the role of the HPS standards process and indicates particular standards under development which will be of interest to the reader. In addition, the authors solicit readers to participate in the voluntary standards process by either joining active working groups (WG) or suggesting appropriate and relevant topics which should be placed into the standards process

  18. Coordination of fictive motor activity in the larval zebrafish is generated by non-segmental mechanisms.

    Directory of Open Access Journals (Sweden)

    Timothy D Wiggin

    Full Text Available The cellular and network basis for most vertebrate locomotor central pattern generators (CPGs is incompletely characterized, but organizational models based on known CPG architectures have been proposed. Segmental models propose that each spinal segment contains a circuit that controls local coordination and sends longer projections to coordinate activity between segments. Unsegmented/continuous models propose that patterned motor output is driven by gradients of neurons and synapses that do not have segmental boundaries. We tested these ideas in the larval zebrafish, an animal that swims in discrete episodes, each of which is composed of coordinated motor bursts that progress rostrocaudally and alternate from side to side. We perturbed the spinal cord using spinal transections or strychnine application and measured the effect on fictive motor output. Spinal transections eliminated episode structure, and reduced both rostrocaudal and side-to-side coordination. Preparations with fewer intact segments were more severely affected, and preparations consisting of midbody and caudal segments were more severely affected than those consisting of rostral segments. In reduced preparations with the same number of intact spinal segments, side-to-side coordination was more severely disrupted than rostrocaudal coordination. Reducing glycine receptor signaling with strychnine reversibly disrupted both rostrocaudal and side-to-side coordination in spinalized larvae without disrupting episodic structure. Both spinal transection and strychnine decreased the stability of the motor rhythm, but this effect was not causal in reducing coordination. These results are inconsistent with a segmented model of the spinal cord and are better explained by a continuous model in which motor neuron coordination is controlled by segment-spanning microcircuits.

  19. Entrustable Professional Activities for Pathology: Recommendations From the College of American Pathologists Graduate Medical Education Committee.

    Science.gov (United States)

    McCloskey, Cindy B; Domen, Ronald E; Conran, Richard M; Hoffman, Robert D; Post, Miriam D; Brissette, Mark D; Gratzinger, Dita A; Raciti, Patricia M; Cohen, David A; Roberts, Cory A; Rojiani, Amyn M; Kong, Christina S; Peterson, Jo Elle G; Johnson, Kristen; Plath, Sue; Powell, Suzanne Zein-Eldin

    2017-01-01

    Competency-based medical education has evolved over the past decades to include the Accreditation Council for Graduate Medical Education Accreditation System of resident evaluation based on the Milestones project. Entrustable professional activities represent another means to determine learner proficiency and evaluate educational outcomes in the workplace and training environment. The objective of this project was to develop entrustable professional activities for pathology graduate medical education encompassing primary anatomic and clinical pathology residency training. The Graduate Medical Education Committee of the College of American Pathologists met over the course of 2 years to identify and define entrustable professional activities for pathology graduate medical education. Nineteen entrustable professional activities were developed, including 7 for anatomic pathology, 4 for clinical pathology, and 8 that apply to both disciplines with 5 of these concerning laboratory management. The content defined for each entrustable professional activity includes the entrustable professional activity title, a description of the knowledge and skills required for competent performance, mapping to relevant Accreditation Council for Graduate Medical Education Milestone subcompetencies, and general assessment methods. Many critical activities that define the practice of pathology fit well within the entrustable professional activity model. The entrustable professional activities outlined by the Graduate Medical Education Committee are meant to provide an initial framework for the development of entrustable professional activity-related assessment and curricular tools for pathology residency training.

  20. Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks

    Science.gov (United States)

    Amin, Hayder; Maccione, Alessandro; Nieus, Thierry

    2017-01-01

    Developing neuronal systems intrinsically generate coordinated spontaneous activity that propagates by involving a large number of synchronously firing neurons. In vivo, waves of spikes transiently characterize the activity of developing brain circuits and are fundamental for activity-dependent circuit formation. In vitro, coordinated spontaneous spiking activity, or network bursts (NBs), interleaved within periods of asynchronous spikes emerge during the development of 2D and 3D neuronal cultures. Several studies have investigated this type of activity and its dynamics, but how a neuronal system generates these coordinated events remains unclear. Here, we investigate at a cellular level the generation of network bursts in spontaneously active neuronal cultures by exploiting high-resolution multielectrode array recordings and computational network modelling. Our analysis reveals that NBs are generated in specialized regions of the network (functional neuronal communities) that feature neuronal links with high cross-correlation peak values, sub-millisecond lags and that share very similar structural connectivity motifs providing recurrent interactions. We show that the particular properties of these local structures enable locally amplifying spontaneous asynchronous spikes and that this mechanism can lead to the initiation of NBs. Through the analysis of simulated and experimental data, we also show that AMPA currents drive the coordinated activity, while NMDA and GABA currents are only involved in shaping the dynamics of NBs. Overall, our results suggest that the presence of functional neuronal communities with recurrent local connections allows a neuronal system to generate spontaneous coordinated spiking activity events. As suggested by the rules used for implementing our computational model, such functional communities might naturally emerge during network development by following simple constraints on distance-based connectivity. PMID:28749937

  1. Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks.

    Directory of Open Access Journals (Sweden)

    Davide Lonardoni

    2017-07-01

    Full Text Available Developing neuronal systems intrinsically generate coordinated spontaneous activity that propagates by involving a large number of synchronously firing neurons. In vivo, waves of spikes transiently characterize the activity of developing brain circuits and are fundamental for activity-dependent circuit formation. In vitro, coordinated spontaneous spiking activity, or network bursts (NBs, interleaved within periods of asynchronous spikes emerge during the development of 2D and 3D neuronal cultures. Several studies have investigated this type of activity and its dynamics, but how a neuronal system generates these coordinated events remains unclear. Here, we investigate at a cellular level the generation of network bursts in spontaneously active neuronal cultures by exploiting high-resolution multielectrode array recordings and computational network modelling. Our analysis reveals that NBs are generated in specialized regions of the network (functional neuronal communities that feature neuronal links with high cross-correlation peak values, sub-millisecond lags and that share very similar structural connectivity motifs providing recurrent interactions. We show that the particular properties of these local structures enable locally amplifying spontaneous asynchronous spikes and that this mechanism can lead to the initiation of NBs. Through the analysis of simulated and experimental data, we also show that AMPA currents drive the coordinated activity, while NMDA and GABA currents are only involved in shaping the dynamics of NBs. Overall, our results suggest that the presence of functional neuronal communities with recurrent local connections allows a neuronal system to generate spontaneous coordinated spiking activity events. As suggested by the rules used for implementing our computational model, such functional communities might naturally emerge during network development by following simple constraints on distance-based connectivity.

  2. The relationship between segmental coordination, agility and physical activity in adolescents

    Directory of Open Access Journals (Sweden)

    Eliseo García Cantó

    2015-06-01

    Full Text Available Motor competence (MC may be related to youth physical activity (PA level. In the last few years, MC has been studied as a possible determinant of children PA level, but has not been widely studied in adolescents. To analyze the relationship between MC and PA level 533 adolescents (271 men and 261 women from the southeast of Spain were assessed. To register weekly PA was used the International Physical Activity Questionnaire (IPAQ and for the MC, four coordination tests including throw and catch test, eye-hand and eye-foot coordination tests and agility circuit. Data were analyzed using ANOVA and binary logistic regression. The overall MC is consistently related with PA level. Eye-hand coordination test and the agility test define more accurately the tendency to high PA level. Programs to promote PA and focused on MC should be emphasized from early ages to adolescence.

  3. Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    This CD-ROM is attached to the booklet 'Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)'. It contains the background material with regard to ANENT in full text, including policy level papers, reports, presentation material made by Member States, and meeting summaries during the period 2002-2005. Further information on the current ANENT activities and related IAEA activities is available at 'http://anent-iaea.org' and 'http://iaea.org/inisnkm'

  4. Muscle activity during functional coordination training: implications for strength gain and rehabilitation

    DEFF Research Database (Denmark)

    Jørgensen, Marie Birk; Andersen, Lars Louis; Kirk, Niels

    2010-01-01

    The purpose of this study was to evaluate if different types, body positions, and levels of progression of functional coordination exercises can provide sufficiently high levels of muscle activity to improve strength of the neck, shoulder, and trunk muscles. Nine untrained women were familiarized...... to the maximal EMG activity during maximal voluntary contractions, and a p value 60% of maximal EMG activity). Type of exercise played a significant role...

  5. Research nurse manager perceptions about research activities performed by non-nurse clinical research coordinators.

    Science.gov (United States)

    Jones, Carolynn Thomas; Hastings, Clare; Wilson, Lynda Law

    2015-01-01

    There has been limited research to document differences in roles between nurses and non-nurses who assume clinical research coordination and management roles. Several authors have suggested that there is no acknowledged guidance for the licensure requirements for research study coordinators and that some non-nurse research coordinators may be assuming roles that are outside of their legal scopes of practice. There is a need for further research on issues related to the delegation of clinical research activities to non-nurses. This study used nominal group process focus groups to identify perceptions of experienced research nurse managers at an academic health science center in the Southern United States about the clinical research activities that are being performed by non-nurse clinical research coordinators without supervision that they believed should only be performed by a nurse or under the supervision of a nurse. A total of 13 research nurse managers volunteered to be contacted about the study. Of those, 8 participated in two separate nominal group process focus group sessions. The group members initially identified 22 activities that they felt should only be performed by a nurse or under the direct supervision of a nurse. After discussion and clarification of results, activities were combined into 12 categories of clinical research activities that participants believed should only be performed by a nurse or under the direct supervision of a nurse. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Leg muscle activation during gait in Parkinson's disease : Adaptation and interlimb coordination

    NARCIS (Netherlands)

    Dietz, [No Value; Zijlstra, W; Prokop, T; Berger, W

    1995-01-01

    Adaptation in leg muscle activity and coordination between lower limbs were studied during walking on a treadmill with split belts in one group of parkinsonian patients and one of age-matched healthy subjects. Four different belt speeds (0.25/0.5/0.75/1.0 m/sec) were applied in selected combinations

  7. Pyrolysis of Helical Coordination Polymers for Metal-Sulfide-Based Helices with Broadband Chiroptical Activity.

    Science.gov (United States)

    Hirai, Kenji; Yeom, Bongjun; Sada, Kazuki

    2017-06-27

    Fabrication of chiroptical materials with broadband response in the visible light region is vital to fully realize their potential applications. One way to achieve broadband chiroptical activity is to fabricate chiral nanostructures from materials that exhibit broadband absorption in the visible light region. However, the compounds used for chiroptical materials have predominantly been limited to materials with narrowband spectral response. Here, we synthesize Ag 2 S-based nanohelices derived from helical coordination polymers. The right- and left-handed coordination helices used as precursors are prepared from l- and d-glutathione with Ag + and a small amount of Cu 2+ . The pyrolysis of the coordination helices yields right- and left-handed helices of Cu 0.12 Ag 1.94 S/C, which exhibit chiroptical activity spanning the entire visible light region. Finite element method simulations substantiate that the broadband chiroptical activity is attributed to synergistic broadband light absorption and light scattering. Furthermore, another series of Cu 0.10 Ag 1.90 S/C nanohelices are synthesized by choosing the l- or d-Glu-Cys as starting materials. The pitch length of nanohelicies is controlled by changing the peptides, which alters their chiroptical properties. The pyrolysis of coordination helices enables one to fabricate helical Ag 2 S-based materials that enable broadband chiroptical activity but have not been explored owing to the lack of synthetic routes.

  8. METHOD FOR DETERMINING THE SPATIAL COORDINATES IN THE ACTIVE STEREOSCOPIC SYSTEM

    Directory of Open Access Journals (Sweden)

    Valery V. Korotaev

    2014-11-01

    Full Text Available The paper deals with the structural scheme of active stereoscopic system and algorithm of its operation, providing the fast calculation of the spatial coordinates. The system includes two identical cameras, forming a stereo pair, and a laser scanner, which provides vertical scanning of the space before the system by the laser beam. A separate synchronizer provides synchronous operation of the two cameras. The developed algorithm of the system operation is implemented in MATLAB. In the proposed algorithm, the influence of background light is eliminated by interframe processing. The algorithm is based on precomputation of coordinates for epipolar lines and corresponding points in stereoscopic image. These data are used to quick calculation of the three-dimensional coordinates of points that form the three-dimensional images of objects. Experiment description on a physical model is given. Experimental results confirm the efficiency of the proposed active stereoscopic system and its operation algorithm. The proposed scheme of active stereoscopic system and calculating method for the spatial coordinates can be recommended for creation of stereoscopic systems, operating in real time and at high processing speed: devices for face recognition, systems for the position control of railway track, automobile active safety systems.

  9. Report of Committee for JAEA Internationalization Initiative. Focusing on the activities of local teams

    International Nuclear Information System (INIS)

    2015-10-01

    The 'Committee for JAEA Internationalization Initiative' was established in 2010 with the view to discuss the policy and improvement plans for JAEA's achievement of an international center of excellence (ICOE), which include improving the environment to accept foreign researchers, etc. The existing issues to be solved in the effort for ICOE and recommendations for the solutions, which were discussed in the committee, and challenges in developing human resources with a global mindset were written in the report summarizing the activities conducted in the following two years. This report was compiled focusing on the efforts in respective sites made during a period of two years from 2013 to 2014 by the local teams that were set up in accordance with the situation of the R and D centers hosting a number of foreign researchers, etc. based on the above-mentioned recommendations. (author)

  10. General activities of JAERI nuclear data center and Japanese nuclear data committee

    International Nuclear Information System (INIS)

    Fukahori, Tokio

    1999-01-01

    The nuclear data center of Japan Atomic Energy Research Institute (JAERI/NDC) is playing the role of Japanese domestic nuclear data center and gateway to foreign data centers. As the domestic nuclear data center, activities of JAERI/NDC are 1) compiling the Japanese Evaluated Nuclear Data Library (JENDL) for both general and special purposes, 2) importing and exporting nuclear data, 3) nuclear data services for the domestic users, and 4) organizing japanese Nuclear Data Committee (JNDC) as a secretariat. Compiled JENDL General Purpose Files up to now are JENDL-1, 2, 3, 3.1 and 3.2. The data for 340 nuclei in the energy range from 10 -5 eV to 20 MeV are available in JENDL-3.2. JENDL Special Purpose Files were also prepared in order to meet the requests from the specified application fields. JNDC has about 140 members. JNDC consists of Main Committee, Steering Committee, Subcommittee on Nuclear Data, Subcommittee on Reactor Constants, Subcommittee on Nuclear Fuel Cycle and Standing Groups. Above subcommittees are performing essential evaluation for the files described above, checking the JENDL files through the benchmark and integral testing as well as considering the standard group constant, and considering about evaluation of decay heat and nuclide generation/depletion and fission product yields. (author)

  11. ACTIVATION OF ACETYLENE BY COORDINATION TO BIS-TRIPHENYLPHOSPHINE COMPLEX OF Pt(0: DFT STUDY

    Directory of Open Access Journals (Sweden)

    N. N. Gorinchoy

    2009-06-01

    Full Text Available The present work is devoted to the theoretical study of the activation of the acetylene molecule coordinated in the [Pt(PPh32C2H2] complex. By means of DFT calculations it is shown that the geometrical and electronic characteristics of the C2H2 are essentially changed due to its coordination. The subsequent detailed analysis of the molecular orbitals (MO of the active valence zone of this complex allows one to make important conclusion that this activation is being realized mainly due to the orbital back donation of 5d-electronic density from one of the occupied MOs of the complex [Pt(PPh32] to the unoccupied antibonding π*-MO of C2H2.

  12. Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid

    Directory of Open Access Journals (Sweden)

    T. O. Aiyelabola

    2016-01-01

    Full Text Available Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus. The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out. This resulted in varying geometrical structures for the complexes. The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard.

  13. Activity report of Japanese Nuclear Data Committee in period of April 1993 to March 1995

    International Nuclear Information System (INIS)

    1995-01-01

    This is a progress report on the activities of the Japanese Nuclear Data Committee (JNDC) in the period of April 1993 to March 1995. In this period, the latest version of the Japanese Evaluated Nuclear Data Library, JENDL-3.2, has been released for users after benchmark tests of data therein. Preparation of the special purpose nuclear data files has been also progressed. As special topics, the followings are presented here : (1) the completion and benchmark tests of the JENDL-3.2, (2) progress in evaluating special purpose nuclear data, (3) progress in studying high energy nuclear data, and (4) utilization of nuclear data by means of internet. (author)

  14. Committee for nuclear safety information and transparency. Activity annual report, June 2008 - December 2009

    International Nuclear Information System (INIS)

    2010-01-01

    After a presentation of the composition, organisation, missions and means of this institution, this report presents the main domain of activity (the transport of plutonium, the SOCATRI incident and submission to the State minister, the nuclear installation dismantling strategy), and the three working groups (transparency and secrets, Internet portal, environment radioactivity index). It reports the taking into account of recommendations previously expressed by the committee (about import and transport of plutonium between Great-Britain and France, about information of population and patients on radiological and nuclear medicine events)

  15. Activity report of Japanese Nuclear Data Committee in period of April 1983 to March 1985

    International Nuclear Information System (INIS)

    1985-01-01

    This is a progress report on the activities of the Japanese Nuclear Data Committee (JNDC) in the period of April 1983 to March 1985. Special topics are presented on improvements of the nuclear data evaluation methodology, on the study of nuclear model parameters, and on a development of the cross section sensitivity and adjustment code system. Application of the nuclear data to new fields such as fuel cycle and to medical science is also reported. Moreover, some tasks to promote the distribution and utilization of the Japanese Evaluated Nuclear Data Library (JENDL) are described. (author)

  16. Organization of the ITER Co-ordinated Technical Activities International Team

    International Nuclear Information System (INIS)

    2001-01-01

    At its meeting in Toronto on 7 November 2001, the ITER Co-ordinated Technical Activities (CTA) project board took note of the organizational arrangements for the CTA International Team at the Garching and Naka joint work sites. The organization chart of the team remains almost unchanged from that of the ITER Engineering Design Activities (EDA). However, there is no special division responsible for plasma and field control. Activities in plasma control will be taken over by the Physics Unit. This newsletter also includes the ITER CTA International Team structure

  17. Twinning in fcc lattice creates low-coordinated catalytically active sites in porous gold

    Energy Technology Data Exchange (ETDEWEB)

    Krajčí, Marian [Institute of Physics, Slovak Academy of Sciences, Dúbravská cesta 9, SK-84511 Bratislava (Slovakia); Kameoka, Satoshi; Tsai, An-Pang [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai 980-8577 (Japan)

    2016-08-28

    We describe a new mechanism for creation of catalytically active sites in porous gold. Samples of porous gold prepared by de-alloying Al{sub 2}Au exhibit a clear correlation between the catalytic reactivity towards CO oxidation and structural defects in the fcc lattice of Au. We have found that on the stepped (211) surfaces quite common twin boundary defects in the bulk structure of porous gold can form long close-packed rows of atoms with the coordination number CN = 6. DFT calculations confirm that on these low-coordinated Au sites dioxygen chemisorbs and CO oxidation can proceed via the Langmuir–Hinshelwood mechanism with the activation energy of 37 kJ/mol or via the CO–OO intermediate with the energy barrier of 19 kJ/mol. The existence of the twins in porous gold is stabilized by the surface energy.

  18. Automatic generation of active coordinates for quantum dynamics calculations: Application to the dynamics of benzene photochemistry

    International Nuclear Information System (INIS)

    Lasorne, Benjamin; Sicilia, Fabrizio; Bearpark, Michael J.; Robb, Michael A.; Worth, Graham A.; Blancafort, Lluis

    2008-01-01

    A new practical method to generate a subspace of active coordinates for quantum dynamics calculations is presented. These reduced coordinates are obtained as the normal modes of an analytical quadratic representation of the energy difference between excited and ground states within the complete active space self-consistent field method. At the Franck-Condon point, the largest negative eigenvalues of this Hessian correspond to the photoactive modes: those that reduce the energy difference and lead to the conical intersection; eigenvalues close to 0 correspond to bath modes, while modes with large positive eigenvalues are photoinactive vibrations, which increase the energy difference. The efficacy of quantum dynamics run in the subspace of the photoactive modes is illustrated with the photochemistry of benzene, where theoretical simulations are designed to assist optimal control experiments

  19. Third research coordination meeting on reference database for neutron activation analysis. Summary report

    International Nuclear Information System (INIS)

    Kellett, M.A.

    2009-12-01

    The third meeting of the Co-ordinated Research Project on 'Reference Database for Neutron Activation Analysis' was held at the IAEA, Vienna from 17-19 November 2008. A summary of presentations made by participants is given, reports on specific tasks and subsequent discussions. With the aim of finalising the work of this CRP and in order to meet initial objectives, outputs were discussed and detailed task assignments agreed upon. (author)

  20. Results of the activities of the Scientific and Technical Coordination Council for Radiation Technique and Technology

    Energy Technology Data Exchange (ETDEWEB)

    Sille, A K [Gosudarstvennyj Komitet po Ispol' zovaniyu Atomnoj Ehnergii SSSR, Moscow

    1977-03-01

    It is reported on the activities of the Scientific and Technical Coordination Council for Radiation Technique and Technology (STCC-RTT) of the CMEA Permanent Commission for the Peaceful Uses of Atomic Energy according to the programme 1971 to 1975. The STCC-RTT is concerned with technical applications such as radiation sterilization, food irradiation, radiation-induced chemical processes etc. The main tasks which have to be solved within the period from 1976 to 1980 are outlined.

  1. Coordinated activation of the secretory pathway during notochord formation in the Xenopus embryo.

    Science.gov (United States)

    Tanegashima, Kosuke; Zhao, Hui; Rebbert, Martha L; Dawid, Igor B

    2009-11-01

    We compared the transcriptome in the developing notochord of Xenopus laevis embryos with that of other embryonic regions. A coordinated and intense activation of a large set of secretory pathway genes was observed in the notochord, but not in notochord precursors in the axial mesoderm at early gastrula stage. The genes encoding Xbp1 and Creb3l2 were also activated in the notochord. These two transcription factors are implicated in the activation of secretory pathway genes during the unfolded protein response, where cells react to the stress of a build-up of unfolded proteins in their endoplasmic reticulum. Xbp1 and Creb3l2 are differentially expressed but not differentially activated in the notochord. Reduction of expression of Xbp1 or Creb3l2 by injection of antisense morpholinos led to strong deficits in notochord but not somitic muscle development. In addition, the expression of some, but not all, genes encoding secretory proteins was inhibited by injection of xbp1 morpholinos. Furthermore, expression of activated forms of Xbp1 or Creb3l2 in animal explants could activate a similar subset of secretory pathway genes. We conclude that coordinated activation of a battery of secretory pathway genes mediated by Xbp1 and Creb/ATF factors is a characteristic and necessary feature of notochord formation.

  2. Fabrication of a PANI/CPs composite material: a feasible method to enhance the photocatalytic activity of coordination polymers.

    Science.gov (United States)

    Xu, Xin-Xin; Cui, Zhong-Ping; Qi, Ji; Liu, Xiao-Xia

    2013-03-21

    To improve the photocatalytic activity of a coordination polymer in the visible light region, polyaniline (PANI) was loaded onto its surface through a facile in situ chemical oxidation polymerization process. The resulting PANI loaded coordination polymer composite materials with excellent stability exhibit significantly higher photocatalytic activities than the pure coordination polymer photocatalyst on the degradation of methyl orange (MO) under visible light irradiation. This enhancement can be ascribed to the introduction of PANI on the surface of the coordination polymer, which leads to efficient separation of photogenerated electron-hole pairs as well as a significant expansion of the photoresponse region. Finally, we discussed the influence of acidity on the morphology and photocatalytic activity of the composite material. An optimal condition to obtain the PANI loaded coordination polymer composite material with excellent photocatalytic activity has been obtained.

  3. Activities of daily living in children with developmental coordination disorder: dressing, personal hygiene, and eating skills.

    Science.gov (United States)

    Summers, Janet; Larkin, Dawne; Dewey, Deborah

    2008-04-01

    In order to understand how age, culture, and problems in motor coordination impact the performance of activities of daily living, we used focus groups and in-depth interviews with Australian and Canadian parents to examine activities of daily living of younger (5-7 years of age) and older (8-9 years of age) children with and without DCD. By comparison with their typically developing age group, children with DCD had more difficulty with dressing, personal hygiene, and eating skills. Difficulties with postural control and fine-motor skills were reported to contribute to poorer performance of activities of daily living. As expected, competence in the performance of activities of daily living improved in the older children with and without DCD and there were few differences in the performance of daily living tasks between typical children in Australia and Canada. Overall, the motor difficulties of children with DCD had a significant impact on performance of a wide range of daily activities.

  4. Activities of the O ampersand M committee history ampersand future perspectives

    International Nuclear Information System (INIS)

    Poulis, D.S.

    1996-01-01

    This paper gives an overview of the Committee on Operation and Maintenance of Nuclear Power Plants, hereafter referred to as the O ampersand M Committee, formed in June 1975 when the American National Standard Institute's Committee on Reactor Plants and their Maintenance was disbanded. The O ampersand M Committee's history, structure, current focus and future perspectives will be presented. The purpose of this paper is to give information to industry and the public of the Committee's on-going effort to make accurate and timely responses to the needs of the nuclear industry

  5. Zinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1.

    Directory of Open Access Journals (Sweden)

    Siddhesh Aras

    2009-06-01

    Full Text Available Epstein-Barr Nuclear Antigen 1 (EBNA1 is essential for Epstein-Barr virus to immortalize naïve B-cells. Upon binding a cluster of 20 cognate binding-sites termed the family of repeats, EBNA1 transactivates promoters for EBV genes that are required for immortalization. A small domain, termed UR1, that is 25 amino-acids in length, has been identified previously as essential for EBNA1 to activate transcription. In this study, we have elucidated how UR1 contributes to EBNA1's ability to transactivate. We show that zinc is necessary for EBNA1 to activate transcription, and that UR1 coordinates zinc through a pair of essential cysteines contained within it. UR1 dimerizes upon coordinating zinc, indicating that EBNA1 contains a second dimerization interface in its amino-terminus. There is a strong correlation between UR1-mediated dimerization and EBNA1's ability to transactivate cooperatively. Point mutants of EBNA1 that disrupt zinc coordination also prevent self-association, and do not activate transcription cooperatively. Further, we demonstrate that UR1 acts as a molecular sensor that regulates the ability of EBNA1 to activate transcription in response to changes in redox and oxygen partial pressure (pO(2. Mild oxidative stress mimicking such environmental changes decreases EBNA1-dependent transcription in a lymphoblastoid cell-line. Coincident with a reduction in EBNA1-dependent transcription, reductions are observed in EBNA2 and LMP1 protein levels. Although these changes do not affect LCL survival, treated cells accumulate in G0/G1. These findings are discussed in the context of EBV latency in body compartments that differ strikingly in their pO(2 and redox potential.

  6. Cdk1 activity acts as a quantitative platform for coordinating cell cycle progression with periodic transcription

    Science.gov (United States)

    Banyai, Gabor; Baïdi, Feriel; Coudreuse, Damien; Szilagyi, Zsolt

    2016-01-01

    Cell proliferation is regulated by cyclin-dependent kinases (Cdks) and requires the periodic expression of particular gene clusters in different cell cycle phases. However, the interplay between the networks that generate these transcriptional oscillations and the core cell cycle machinery remains largely unexplored. In this work, we use a synthetic regulable Cdk1 module to demonstrate that periodic expression is governed by quantitative changes in Cdk1 activity, with different clusters directly responding to specific activity levels. We further establish that cell cycle events neither participate in nor interfere with the Cdk1-driven transcriptional program, provided that cells are exposed to the appropriate Cdk1 activities. These findings contrast with current models that propose self-sustained and Cdk1-independent transcriptional oscillations. Our work therefore supports a model in which Cdk1 activity serves as a quantitative platform for coordinating cell cycle transitions with the expression of critical genes to bring about proper cell cycle progression. PMID:27045731

  7. Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels

    Science.gov (United States)

    Delorme-Walker, Violaine; Seo, Ji-Yeon; Gohla, Antje; Fowler, Bruce; Bohl, Ben; DerMardirossian, Céline

    2015-01-01

    Cofilin, a critical player of actin dynamics, is spatially and temporally regulated to control the direction and force of membrane extension required for cell locomotion. In carcinoma cells, although the signaling pathways regulating cofilin activity to control cell direction have been established, the molecular machinery required to generate the force of the protrusion remains unclear. We show that the cofilin phosphatase chronophin (CIN) spatiotemporally regulates cofilin activity at the cell edge to generate persistent membrane extension. We show that CIN translocates to the leading edge in a PI3-kinase–, Rac1-, and cofilin-dependent manner after EGF stimulation to activate cofilin, promotes actin free barbed end formation, accelerates actin turnover, and enhances membrane protrusion. In addition, we establish that CIN is crucial for the balance of protrusion/retraction events during cell migration. Thus, CIN coordinates the leading edge dynamics by controlling active cofilin levels to promote MTLn3 cell protrusion. PMID:26324884

  8. Shared investment projects and forecasting errors: setting framework conditions for coordination and sequencing data quality activities.

    Science.gov (United States)

    Leitner, Stephan; Brauneis, Alexander; Rausch, Alexandra

    2015-01-01

    In this paper, we investigate the impact of inaccurate forecasting on the coordination of distributed investment decisions. In particular, by setting up a computational multi-agent model of a stylized firm, we investigate the case of investment opportunities that are mutually carried out by organizational departments. The forecasts of concern pertain to the initial amount of money necessary to launch and operate an investment opportunity, to the expected intertemporal distribution of cash flows, and the departments' efficiency in operating the investment opportunity at hand. We propose a budget allocation mechanism for coordinating such distributed decisions The paper provides guidance on how to set framework conditions, in terms of the number of investment opportunities considered in one round of funding and the number of departments operating one investment opportunity, so that the coordination mechanism is highly robust to forecasting errors. Furthermore, we show that-in some setups-a certain extent of misforecasting is desirable from the firm's point of view as it supports the achievement of the corporate objective of value maximization. We then address the question of how to improve forecasting quality in the best possible way, and provide policy advice on how to sequence activities for improving forecasting quality so that the robustness of the coordination mechanism to errors increases in the best possible way. At the same time, we show that wrong decisions regarding the sequencing can lead to a decrease in robustness. Finally, we conduct a comprehensive sensitivity analysis and prove that-in particular for relatively good forecasters-most of our results are robust to changes in setting the parameters of our multi-agent simulation model.

  9. Shared Investment Projects and Forecasting Errors: Setting Framework Conditions for Coordination and Sequencing Data Quality Activities

    Science.gov (United States)

    Leitner, Stephan; Brauneis, Alexander; Rausch, Alexandra

    2015-01-01

    In this paper, we investigate the impact of inaccurate forecasting on the coordination of distributed investment decisions. In particular, by setting up a computational multi-agent model of a stylized firm, we investigate the case of investment opportunities that are mutually carried out by organizational departments. The forecasts of concern pertain to the initial amount of money necessary to launch and operate an investment opportunity, to the expected intertemporal distribution of cash flows, and the departments’ efficiency in operating the investment opportunity at hand. We propose a budget allocation mechanism for coordinating such distributed decisions The paper provides guidance on how to set framework conditions, in terms of the number of investment opportunities considered in one round of funding and the number of departments operating one investment opportunity, so that the coordination mechanism is highly robust to forecasting errors. Furthermore, we show that—in some setups—a certain extent of misforecasting is desirable from the firm’s point of view as it supports the achievement of the corporate objective of value maximization. We then address the question of how to improve forecasting quality in the best possible way, and provide policy advice on how to sequence activities for improving forecasting quality so that the robustness of the coordination mechanism to errors increases in the best possible way. At the same time, we show that wrong decisions regarding the sequencing can lead to a decrease in robustness. Finally, we conduct a comprehensive sensitivity analysis and prove that—in particular for relatively good forecasters—most of our results are robust to changes in setting the parameters of our multi-agent simulation model. PMID:25803736

  10. Shared investment projects and forecasting errors: setting framework conditions for coordination and sequencing data quality activities.

    Directory of Open Access Journals (Sweden)

    Stephan Leitner

    Full Text Available In this paper, we investigate the impact of inaccurate forecasting on the coordination of distributed investment decisions. In particular, by setting up a computational multi-agent model of a stylized firm, we investigate the case of investment opportunities that are mutually carried out by organizational departments. The forecasts of concern pertain to the initial amount of money necessary to launch and operate an investment opportunity, to the expected intertemporal distribution of cash flows, and the departments' efficiency in operating the investment opportunity at hand. We propose a budget allocation mechanism for coordinating such distributed decisions The paper provides guidance on how to set framework conditions, in terms of the number of investment opportunities considered in one round of funding and the number of departments operating one investment opportunity, so that the coordination mechanism is highly robust to forecasting errors. Furthermore, we show that-in some setups-a certain extent of misforecasting is desirable from the firm's point of view as it supports the achievement of the corporate objective of value maximization. We then address the question of how to improve forecasting quality in the best possible way, and provide policy advice on how to sequence activities for improving forecasting quality so that the robustness of the coordination mechanism to errors increases in the best possible way. At the same time, we show that wrong decisions regarding the sequencing can lead to a decrease in robustness. Finally, we conduct a comprehensive sensitivity analysis and prove that-in particular for relatively good forecasters-most of our results are robust to changes in setting the parameters of our multi-agent simulation model.

  11. Co-ordinated research activities: Annual report and statistics for 2003

    International Nuclear Information System (INIS)

    2004-07-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These co-ordinated research activities are normally implemented through Co-ordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports several Doctoral CRPs. This new, optional type of CRP has been designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs are currently being carried out by the Human Health programme. Further information on the Agency's co-ordinated research activities, including current information on CRPs and programme areas supported, information on policies and procedures and the administration of the activities is contained in the Agency's website at http://www-crp.iaea.org. The co-ordinated research activities reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Material Technologies; Analysis for Sustainable

  12. Co-ordinated research activities: Annual report and statistics for 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These co-ordinated research activities are normally implemented through Co-ordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports several Doctoral CRPs. This new, optional type of CRP has been designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs are currently being carried out by the Human Health programme. Further information on the Agency's co-ordinated research activities, including current information on CRPs and programme areas supported, information on policies and procedures and the administration of the activities is contained in the Agency's website at http://www-crp.iaea.org. The co-ordinated research activities reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Material Technologies; Analysis for Sustainable

  13. Impact of Coordinated-Bilateral Physical Activities on Attention and Concentration in School-Aged Children

    Directory of Open Access Journals (Sweden)

    Heidi Buchele Harris

    2018-01-01

    Full Text Available Purpose. This study examined the effects of 4-week, daily 6-minute coordinated-bilateral physical activity (CBPA breaks in classroom on attention and concentration in school-aged children. Methods. Participants (n=116 in fifth grade from two elementary schools were assigned to three groups: two intervention groups (n= 60 and one control group (n = 56. All three groups were pre- and post-tested with the d2 Test of Attention (d2 test. One intervention group (n = 31 took part in six minutes of daily classroom-based coordinated-bilateral physical activity (CBPA break for four weeks. Another intervention group (n = 29, the Fitbit Only (Fitbit-O, wore Fitbits per day during a school, five days per week for four weeks without CBPA breaks. A 2 × 3 ANOVA was conducted, followed by the post hoc comparisons. Results. The CBPA showed significant increases in processing speed (F1 = 6.876, p = .010, focused attention (F1 = 10.688, p = .002, concentration performance (F1 = 26.46, p = .000, and attention span (F1 = 14.090, p = .000 over the control, but not in accuracy (Error %. The CBPA showed significant improvement in concentration performance (F1 = 24.162, p = .000 and attention span (F1 = 6.891, p = .011, compared to the Fitbit-O. No significant changes in all five attention parameters were found between the Fitbit-O and the control. Conclusion. It was concluded that daily brief coordinated-bilateral activities can improve attention and concentration in fifth-grade students over the course of four weeks.

  14. A Control Architecture to Coordinate Distributed Generators and Active Power Filters Coexisting in a Microgrid

    DEFF Research Database (Denmark)

    Hashempour, Mohammad M.; Firoozabadi, Mehdi Savaghebi; Quintero, Juan Carlos Vasquez

    2016-01-01

    This paper proposes a control architecture of distributed generators (DGs) inverters and shunt active power filters (APFs) in microgrids to compensate voltage harmonics in a coordinated way. For this, a hierarchical control structure is proposed that includes two control levels. The primary (local......) control consists of power controllers, selective virtual impedance loops and proportional-resonant (PR) voltage/current controllers. The secondary (central) control manages the compensation level of voltage harmonic distortion of sensitive load bus (SLB). Compensation of SLB harmonics by control of DGs...... excessive harmonics or overloading of interface inverters. Effectiveness of the proposed control scheme is demonstrated through simulation studies....

  15. A control architecture to coordinate distributed generators and active power filters coexisting in a microgrid

    DEFF Research Database (Denmark)

    Hashempour, Mohammad M.; Savaghebi, Mehdi; Quintero, Juan Carlos Vasquez

    2016-01-01

    This paper proposes a control architecture of distributed generators (DGs) inverters and shunt active power filters (APFs) in microgrids to compensate voltage harmonics in a coordinated way. For this, a hierarchical control structure is proposed that includes two control levels. The primary (local......) control consists of power controllers, selective virtual impedance loops and proportional-resonant (PR) voltage/current controllers. The secondary (central) control manages the compensation level of voltage harmonic distortion of sensitive load bus (SLB). Compensation of SLB harmonics by control of DGs...... excessive harmonics or overloading of interface inverters. Effectiveness of the proposed control scheme is demonstrated through simulation studies....

  16. PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.

    Science.gov (United States)

    Shrestha, Y; Schafer, E J; Boehm, J S; Thomas, S R; He, F; Du, J; Wang, S; Barretina, J; Weir, B A; Zhao, J J; Polyak, K; Golub, T R; Beroukhim, R; Hahn, W C

    2012-07-19

    Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of the RAS-RAF-MEK-ERK MAPK pathway is commonly observed in human breast cancers, suggesting that other genetic alterations lead to activation of this signaling pathway. To identify breast cancer oncogenes that activate the MAPK pathway, we screened a library of human kinases for their ability to induce anchorage-independent growth in a derivative of immortalized human mammary epithelial cells (HMLE). We identified p21-activated kinase 1 (PAK1) as a kinase that permitted HMLE cells to form anchorage-independent colonies. PAK1 is amplified in several human cancer types, including 30--33% of breast tumor samples and cancer cell lines. The kinase activity of PAK1 is necessary for PAK1-induced transformation. Moreover, we show that PAK1 simultaneously activates MAPK and MET signaling; the latter via inhibition of merlin. Disruption of these activities inhibits PAK1-driven anchorage-independent growth. These observations establish PAK1 amplification as an alternative mechanism for MAPK activation in human breast cancer and credential PAK1 as a breast cancer oncogene that coordinately regulates multiple signaling pathways, the cooperation of which leads to malignant transformation.

  17. Drug and therapeutics committees in Danish hospitals: a survey of organization, activities and drug selection procedures

    DEFF Research Database (Denmark)

    Plet, H. T.; Hallas, J.; Nielsen, Gitte S.

    2013-01-01

    To implement rational pharmacotherapy in hospitals, it is important to develop, implement and evaluate hospital drug formularies (HDFs). A report from Denmark recommended standardizing activities of the drug and therapeutics committees (DTCs) in Denmark, but little is known about their current...... organization. The aim of the study was to describe the organization of DTCs in Denmark, how HDFs are developed and implemented, and to what extent policies that support the use of HDFs exist. A questionnaire was developed based on previous research and guidelines and contained 20 questions, which were divided...... of the meetings lasted between 1 and 2.5 hr. Eight (89%) DTCs developed HDFs, policies and guidelines (P&Gs) that supported the use of HDFs. Eight (89%) had established criteria for inclusion of drugs on the HDFs, and seven had developed criteria for generic substitution and therapeutic interchange. The number...

  18. Report of International NanoSPD Steering Committee and statistics on recent NanoSPD activities

    International Nuclear Information System (INIS)

    Valiev, R Z; Langdon, T G

    2014-01-01

    Abstract. The Université de Lorraine in Metz, France, is the selected site for the 6th International Conference on Nanomaterials by Severe Plastic Deformation (NanoSPD6) following a series of five earlier conferences. This introductory paper reports on several major developments in NanoSPD activities as well as on very recent NanoSPD citation data which confirm the continued growth and expansion of this important research area. Close attention is given to the topics of workshops, conferences and seminars organized during these last three years as well as on books and reviews published prior to the NanoSPD6 conference. A special concern of the committee is in introducing and discussing the appropriate terminology to be applied in this new field of materials science and engineering

  19. Resilience and Brittleness in a Nuclear Emergency Response Simulation: Focusing on Team Coordination Activity

    International Nuclear Information System (INIS)

    Costa, Wagner Schenkel; Buarque, Lia; Voshell, Martin; Branlat, Matthieu; Woods, David D.; Gomes, Jose Orlando

    2008-01-01

    The current work presents results from a cognitive task analysis (CTA) of a nuclear disaster simulation. Audio-visual records were collected from an emergency room team composed of individuals from 26 different agencies as they responded to multiple scenarios in a simulated nuclear disaster. This simulation was part of a national emergency response training activity for a nuclear power plant located in a developing country. The objectives of this paper are to describe sources of resilience and brittleness in these activities, identify cues of potential improvements for future emergency simulations, and leveraging the resilience of the emergency response System in case of a real disaster. Multiple CTA techniques were used to gain a better understanding of the cognitive dimensions of the activity and to identify team coordination and crisis management patterns that emerged from the simulation training. (authors)

  20. Social Activity and Cognitive Functioning Over Time: A Coordinated Analysis of Four Longitudinal Studies

    Directory of Open Access Journals (Sweden)

    Cassandra L. Brown

    2012-01-01

    Full Text Available Social activity is typically viewed as part of an engaged lifestyle that may help mitigate the deleterious effects of advanced age on cognitive function. As such, social activity has been examined in relation to cognitive abilities later in life. However, longitudinal evidence for this hypothesis thus far remains inconclusive. The current study sought to clarify the relationship between social activity and cognitive function over time using a coordinated data analysis approach across four longitudinal studies. A series of multilevel growth models with social activity included as a covariate is presented. Four domains of cognitive function were assessed: reasoning, memory, fluency, and semantic knowledge. Results suggest that baseline social activity is related to some, but not all, cognitive functions. Baseline social activity levels failed to predict rate of decline in most cognitive abilities. Changes in social activity were not consistently associated with cognitive functioning. Our findings do not provide consistent evidence that changes in social activity correspond to immediate benefits in cognitive functioning, except perhaps for verbal fluency.

  1. Dynamic Shift Coordinated Control Based on Motor Active Speed Synchronization with the New Hybrid System

    Directory of Open Access Journals (Sweden)

    Ting Yan

    2017-01-01

    Full Text Available Considering the inherent disadvantages that severely affect driving comfortability during the shift process in HEVs, a dynamic shift coordinated control based on motor active speed synchronization is proposed to improve shift quality by reduction of shift vibration. The whole control scheme is comprised of three phases, preparatory phase, speed regulation phase, and synchronization phase, which are implemented consecutively in order. The key to inhibiting impact and jerk depends on the speed regulation phase, where motor active speed synchronization is utilized to reach the minimum speed difference between the two ends of synchronizer. A new hybrid system with superior performances is applied to present the validity of the adopted control algorithm during upshift or downshift, which can represent planetary gear system and conventional AMT shift procedure, respectively. Bench test, simulation, and road test results show that, compared with other methods, the proposed dynamic coordinated control can achieve shifting control in real time to effectively improve gear-shift comfort and shorten power interruption transients, with robustness in both conventional AMT and planetary gear train.

  2. Role of communication systems in coordinating supervising anesthesiologists' activities outside of operating rooms.

    Science.gov (United States)

    Smallman, Bettina; Dexter, Franklin; Masursky, Danielle; Li, Fenghua; Gorji, Reza; George, Dave; Epstein, Richard H

    2013-04-01

    Theoretically, communication systems have the potential to increase the productivity of anesthesiologists supervising anesthesia providers. We evaluated the maximal potential of communication systems to increase the productivity of anesthesia care by enhancing anesthesiologists' coordination of care (activities) among operating rooms (ORs). At hospital A, data for 13,368 pages were obtained from files recorded in the internal alphanumeric text paging system. Pages from the postanesthesia care unit were processed through a numeric paging system and thus not included. At hospital B, in a different US state, 3 of the authors categorized each of 898 calls received using the internal wireless audio system (Vocera(®)). Lower and upper 95% confidence limits for percentages are the values reported. At least 45% of pages originated from outside the ORs (e.g., 20% from holding area) at hospital A and at least 56% of calls (e.g., 30% administrative) at hospital B. In contrast, requests from ORs for urgent presence of the anesthesiologist were at most 0.2% of pages at hospital A and 1.8% of calls at hospital B. Approximately half of messages to supervising anesthesiologists are for activity originating outside the ORs being supervised. To use communication tools to increase anesthesia productivity on the day of surgery, their use should include a focus on care coordination outside ORs (e.g., holding area) and among ORs (e.g., at the control desk).

  3. SATB1 packages densely-looped, transciptionally-active chromatinfor coordinated expression of cytokine genes

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Shutao; Lee, Charles C.; Kohwi-Shigematsu, Terumi

    2006-05-23

    SATB1 is an important regulator of nuclear architecture that anchors specialized DNA sequences onto its cage-like network and recruits chromatin remodeling/modifying factors to control gene transcription. We studied the role of SATB1 in regulating the coordinated expression of Il5, Il4, and Il13 from the 200kb cytokine gene cluster region of mouse chromosome 11 during T-helper 2 (Th2)-cell activation. We show that upon cell activation, SATB1 is rapidly induced to form a unique transcriptionally-active chromatin structure that includes the cytokine gene region. Chromatin is folded into numerous small loops all anchored by SATB1, is histone H3 acetylated at lysine 9/14, and associated with Th2-specific factors, GATA3, STAT6, c-Maf, the chromatin-remodeling enzyme Brg-1, and RNA polymerase II across the 200kb region. Before activation, the chromatin displays some of these features, such as association with GATA3 and STAT6, but these were insufficient for cytokine gene expression. Using RNA interference (RNAi), we show that upon cell activation, SATB1 is not only required for chromatin folding into dense loops, but also for c-Maf induction and subsequently for Il4, Il5, and Il13 transcription. Our results show that SATB1 is an important determinant for chromatin architecture that constitutes a novel higher-order, transcriptionally-active chromatin structure upon Th2-cell activation.

  4. Coordination chemistry of oxovanadium(V) complexes with active Schiff bases: synthetic, spectral, and antimicrobial approach

    International Nuclear Information System (INIS)

    Garg, R; Fahmi, N.; Singh, R.V.

    2007-01-01

    The Schiff bases, 3-(indolin-2-one)hydrazinecarbothioamide, 3-(indolin-2-one)hydrazinecarboxamide, 5,6-dimethyl-3-(indolin-2-one)hydrazinecarbothioamide, and 5,6-dimethyl-3-(indolin-2-one)hydrazinecarboxamide, have been synthesized by the condensation of 1H-indol-2,3-dione and 5,6-dimethyl-1H-indol-2,3-dione with the corresponding hydrazinecarbothioamide and hydrazinecarboxamide, respectively. The complexes of oxovanadium and ligands have been characterized by elemental analyses, melting points, conductance measurements, molecular weight determinations, and IR, 1 H NMR and UV spectral studies. These studies showed that the ligands coordinated to the oxovanadium in a monobasic bidentate fashion through oxygen or sulfur and the nitrogen donor system. Thus, penta- and hexa coordinated environment around the vanadium atom has been proposed. All the complexes and their parent organic moieties have been screened for their biological activity on several pathogenic fungi and bacteria and were found to possess appreciable fungicidal and bactericidal properties [ru

  5. A New 1D Chained Coordination Polymer: Synthesis, Crystal Structure, Antitumor Activity and Luminescent Property

    Directory of Open Access Journals (Sweden)

    Xi-Shi Tai

    2015-11-01

    Full Text Available A new 1D chained coordination polymer of Zn(II, {[Zn(L2(4,4′-bipy]·(H2O}n(1 (HL = N-acetyl-l-phenylalanine; 4,4′-bipy = 4,4′-bipyridine has been synthesized and characterized by elemental analysis, IR and X-ray single crystal diffraction analysis. Theresults show that each asymmetric unit of Zn(II complex belongs to monoclinic, space group P21 with a = 11.421(2 Å, b = 9.2213(17 Å, c = 15.188(3 Å,β = 106.112(3°, V = 1536.7(5 Å3, Z = 2, Dc = 1.444 g·cm−3, µ = 0.857 mm−1, F(000 = 696, and final R1 = 0.0439, ωR2 = 0.1013. The molecules form one-dimensional chained structure by its the bridging 4,4′-bipyridine ligands. The antitumor activities and luminescent properties of Zn(II coordination polymer have also been investigated.

  6. Impact of the economic crisis on the activity of a clinical research ethics committee

    Directory of Open Access Journals (Sweden)

    Paula Arcenillas

    2014-11-01

    Full Text Available Purpose: Analyze the impact of economic and social crisis in volume and funding of clinical trials (CT and observational studies (ES from the activity of an Research Ethics Committee (REC. Method: REC memories 2003-2012 were reviewed. Financing of evaluated projects, CT and OS were analyzed classifying them into four groups: 1 promoted by pharmaceutical industry, 2 by scientific societies with industry support, 3 by scientific societies with government support and 4 unfunding.Two periods were compared: pre-crisis (2003-2007 and crisis (2008-2012. Results: During 10 studied years, 744 protocols were evaluated: a 71% of group 1, a 9% of group 2, a 3% of group 3 and a 17% was no funding. Regarding OS, 40%, 5,4%, 8,6% and 46% were the groups 1, 2, 3 and 4 respectively. Analyzing crisis versus pre-crisis period, statistically significant differences were observed in the decreasing of number of CT phase 2 and 3 and in the rising EO. Comparing crisis related to the pre-crisis period, the Group 4 increased statistically significantly. Conclusions: Evolution of total number of studies evaluated by REC tends to be maintained and even increased over time. REC maintains its activity and even increased at the expense of financing and unfunded OS.

  7. [Impact of the economic crisis on the activity of a clinical research ethics committee].

    Science.gov (United States)

    Redondo Capafons, S; Arcenillas, Paula; Giménez, Nuria; March López, Pablo; Soriano, Laura; Pla, Ramon; Quintana, Salvador

    2014-11-03

    Analyze the impact of economic and social crisis in volume and funding of clinical trials (CT) and observational studies (ES) from the activity of an Research Ethics Committee (REC). REC memories 2003-2012 were reviewed. Financing of evaluated projects, CT and OS were analyzed classifying them into four groups: 1) promoted by pharmaceutical industry, 2) by scientific societies with industry support, 3) by scientific societies with government support and 4) unfunding.Two periods were compared: pre-crisis (2003-2007) and crisis (2008-2012). During 10 studied years, 744 protocols were evaluated: a 71% of group 1, a 9% of group 2, a 3% of group 3 and a 17% was no funding. Regarding OS, 40%, 5,4%, 8,6% and 46% were the groups 1, 2, 3 and 4 respectively. Analyzing crisis versus pre-crisis period, statistically significant differences were observed in the decreasing of number of CT phase 2 and 3 and in the rising EO. Comparing crisis related to the pre-crisis period, the Group 4 increased statistically significantly. Evolution of total number of studies evaluated by REC tends to be maintained and even increased over time. REC maintains its activity and even increased at the expense of financing and unfunded OS. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  8. The Coordination and Activity Tracking in CHildren (CATCH) study: rationale and design.

    Science.gov (United States)

    Cairney, John; Missiuna, Cheryl; Timmons, Brian W; Rodriguez, Christine; Veldhuizen, Scott; King-Dowling, Sara; Wellman, Sarah; Le, Tuyen

    2015-12-21

    Past studies have found that children with Developmental Coordination Disorder (DCD) engage in less physical activity than typically developing children. This "activity deficit" may result in children with DCD being less physically fit and more likely to be overweight or obese, potentially increasing later risk for poor cardiovascular health. Unfortunately, the majority of DCD research has been limited to cross-sectional designs, leading to questions about the complex relationship among motor ability, inactivity and health-related fitness. Of the few longitudinal studies on the topic, determining precedence amongst these factors is difficult because study cohorts typically focus on mid to late childhood. By this age, both decreased physical fitness and obesity are often established. The Coordination and Activity Tracking in CHildren (CATCH) study will examine the pathways connecting DCD, physical activity, physical fitness, and body composition from early to middle childhood. The CATCH study is a prospective cohort study. We aim to recruit a cohort of 600 children aged 4 to 5 years (300 probable DCD [pDCD] and 300 controls) and test them once a year for 4 years. At Phase 1 of baseline testing, we assess motor skills, cognitive ability (IQ), basic anthropometry, flexibility and lower body muscle strength, while parents complete an interview and questionnaires regarding family demographics, their child's physical activity, and behavioural characteristics. Children who move on to Phase 2 (longitudinal cohort) have their body fat percentage, foot structure, aerobic and anaerobic fitness assessed. An accelerometer to measure physical activity is then given to the child and interested family members. The family also receives an accelerometer logbook and 3-day food dairy. At years 2 to 4, children in the longitudinal cohort will have all baseline assessments repeated (excluding the IQ test), and complete an additional measure of perceived self-efficacy. Parents will

  9. Coordination of atmospheric dispersion activities for the real-time decision support system RODOS

    International Nuclear Information System (INIS)

    Mikkelsen, T.

    1997-05-01

    This projects task has been to coordinate activities among the RODOS Atmospheric Dispersion sub-group A participants, with the overall objective of developing and integrating an atmospheric transport and dispersion module for the joint European Real-time On-line DecisiOn Support system RODOS headed by FZK (formerly KfK), Germany. The project's final goal is the establishment of a fully operational, system-integrated atmospheric transport module for the RODOS system by year 2000, capable of consistent now- and forecasting of radioactive airborne spread over all types of terrain and on all scales of interest, including in particular complex terrain and the different scales of operation, such as the local, the national and the European scale. (au)

  10. Correlation between the structure and biological activity studies of supramolecular coordination azodye compounds

    Directory of Open Access Journals (Sweden)

    M.I. Abou-Dobara

    2017-02-01

    Full Text Available A series of novel bidentate azodye quinoline ligands were synthesized with various p-aromatic amines like p-(OCH3, CH3, H, Cl and NO2. Novel azodye (HLn and complexes [Cu(II/Ni(II] of these ligands have been characterized on the basis of elemental analysis, molar conductance and magnetic measurements, infrared and electronic spectral studies. Suitable structures have been proposed for these complexes. The synthesized ligands and their metal complexes were screened for their antimicrobial activity against four local bacterial species, two Gram positive bacteria (Bacillus cereus and Staphylococcus aureus and two Gram negative bacteria (Escherichia coli and Klebsiella pneumoniae as well as against four local fungal species; namely Aspergillus niger, Alternaria alternata, Penicillium italicum and Fusarium oxysporium. The tested compounds have good antibacterial activity against B. cereus, E. coli and K. pneumoniae. Very low effect was detected against S. aureus and F. oxysporium. We found that the results of antifungal activity of HLn revealed that the complexes are more toxic than ligands against fungi due to the transition metal involved in the coordination. Also Cu2+ complexes are more active than Ni2+ complexes against B. cereus, E. coli and K. pneumoniae. The size of the clear zone was in the following order p-(OCH3 < CH3 < H < Cl < NO2 as expected from Hammett’s constants σR.

  11. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.

    Science.gov (United States)

    Kant, Shashi; Standen, Claire L; Morel, Caroline; Jung, Dae Young; Kim, Jason K; Swat, Wojciech; Flavell, Richard A; Davis, Roger J

    2017-09-19

    Obesity is a major risk factor for the development of metabolic syndrome and type 2 diabetes. How obesity contributes to metabolic syndrome is unclear. Free fatty acid (FFA) activation of a non-receptor tyrosine kinase (SRC)-dependent cJun NH 2 -terminal kinase (JNK) signaling pathway is implicated in this process. However, the mechanism that mediates SRC-dependent JNK activation is unclear. Here, we identify a role for the scaffold protein JIP1 in SRC-dependent JNK activation. SRC phosphorylation of JIP1 creates phosphotyrosine interaction motifs that bind the SH2 domains of SRC and the guanine nucleotide exchange factor VAV. These interactions are required for SRC-induced activation of VAV and the subsequent engagement of a JIP1-tethered JNK signaling module. The JIP1 scaffold protein, therefore, plays a dual role in FFA signaling by coordinating upstream SRC functions together with downstream effector signaling by the JNK pathway. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  12. A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress

    Directory of Open Access Journals (Sweden)

    Shashi Kant

    2017-09-01

    Full Text Available Obesity is a major risk factor for the development of metabolic syndrome and type 2 diabetes. How obesity contributes to metabolic syndrome is unclear. Free fatty acid (FFA activation of a non-receptor tyrosine kinase (SRC-dependent cJun NH2-terminal kinase (JNK signaling pathway is implicated in this process. However, the mechanism that mediates SRC-dependent JNK activation is unclear. Here, we identify a role for the scaffold protein JIP1 in SRC-dependent JNK activation. SRC phosphorylation of JIP1 creates phosphotyrosine interaction motifs that bind the SH2 domains of SRC and the guanine nucleotide exchange factor VAV. These interactions are required for SRC-induced activation of VAV and the subsequent engagement of a JIP1-tethered JNK signaling module. The JIP1 scaffold protein, therefore, plays a dual role in FFA signaling by coordinating upstream SRC functions together with downstream effector signaling by the JNK pathway.

  13. Co-ordinated Research Projects (CRPs): Annual report of activities and statistics for 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-15

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. The research work is normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. In addition, the introduction of a new type of CRP (called Thematic CRP), meant to complement traditional CRPs, is currently being tested by the Human Health programme. This new, optional type of CRP is designed to strengthen promotion of research on nuclear technologies in developing Member States through CRPs that rest on pair building between agreement holders and contract holders and includes a PhD training programme at the contract holders' institutions. Further details of the administration of research contracts and general information on CRPs is contained in the Agency?s Website at http://www.iaea.org/programmes/ri/uc.html. The CRPs reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Waste Management Technology; Comparative Assessment for Sustainable Energy Development; Food and Agriculture; Human Health; Marine Environment and Water Resources; Applications of Physical and Chemical Sciences; Nuclear Safety; Radiation Safety; Radioactive Waste Safety; Co-ordination of Safety Activities; Safeguards. The Sub-programmes supported by the CRPs are listed. Results of research are available to all Member States, and are disseminated through national

  14. Co-ordinated Research Projects (CRPs): Annual report of activities and statistics for 2001

    International Nuclear Information System (INIS)

    2002-07-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. The research work is normally implemented through Coordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. In addition, the introduction of a new type of CRP (called Thematic CRP), meant to complement traditional CRPs, is currently being tested by the Human Health programme. This new, optional type of CRP is designed to strengthen promotion of research on nuclear technologies in developing Member States through CRPs that rest on pair building between agreement holders and contract holders and includes a PhD training programme at the contract holders' institutions. Further details of the administration of research contracts and general information on CRPs is contained in the Agency?s Website at http://www.iaea.org/programmes/ri/uc.html. The CRPs reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Waste Management Technology; Comparative Assessment for Sustainable Energy Development; Food and Agriculture; Human Health; Marine Environment and Water Resources; Applications of Physical and Chemical Sciences; Nuclear Safety; Radiation Safety; Radioactive Waste Safety; Co-ordination of Safety Activities; Safeguards. The Sub-programmes supported by the CRPs are listed. Results of research are available to all Member States, and are disseminated through national

  15. Using Wavelet Entropy to Demonstrate how Mindfulness Practice Increases Coordination between Irregular Cerebral and Cardiac Activities.

    Science.gov (United States)

    Sik, Hin Hung; Gao, Junling; Fan, Jicong; Wu, Bonnie Wai Yan; Leung, Hang Kin; Hung, Yeung Sam

    2017-05-10

    In both the East and West, traditional teachings say that the mind and heart are somehow closely correlated, especially during spiritual practice. One difficulty in proving this objectively is that the natures of brain and heart activities are quite different. In this paper, we propose a methodology that uses wavelet entropy to measure the chaotic levels of both electroencephalogram (EEG) and electrocardiogram (ECG) data and show how this may be used to explore the potential coordination between the mind and heart under different experimental conditions. Furthermore, Statistical Parametric Mapping (SPM) was used to identify the brain regions in which the EEG wavelet entropy was the most affected by the experimental conditions. As an illustration, the EEG and ECG were recorded under two different conditions (normal rest and mindful breathing) at the beginning of an 8-week standard Mindfulness-based Stress Reduction (MBSR) training course (pretest) and after the course (posttest). Using the proposed method, the results consistently showed that the wavelet entropy of the brain EEG decreased during the MBSR mindful breathing state as compared to that during the closed-eye resting state. Similarly, a lower wavelet entropy of heartrate was found during MBSR mindful breathing. However, no difference in wavelet entropy during MBSR mindful breathing was found between the pretest and posttest. No correlation was observed between the entropy of brain waves and the entropy of heartrate during normal rest in all participants, whereas a significant correlation was observed during MBSR mindful breathing. Additionally, the most well-correlated brain regions were located in the central areas of the brain. This study provides a methodology for the establishment of evidence that mindfulness practice (i.e., mindful breathing) may increase the coordination between mind and heart activities.

  16. GIT2 acts as a systems-level coordinator of neurometabolic activity and pathophysiological aging

    Directory of Open Access Journals (Sweden)

    Bronwen eMartin

    2016-01-01

    Full Text Available Aging represents one of the most complicated and highly integrated somatic processes. Healthy aging is suggested to rely upon the coherent regulation of hormonal and neuronal communication between the central nervous system and peripheral tissues. The hypothalamus is one of the main structures in the body responsible for sustaining an efficient interaction between energy balance and neurological activity and therefore likely coordinates multiple systems in the aging process. We previously identified, in hypothalamic and peripheral tissues, the G protein-coupled receptor kinase interacting protein 2 (GIT2 as a stress response and aging regulator. As metabolic status profoundly affects aging trajectories we investigated the role of GIT2 in regulating metabolic activity. We found that genomic deletion of GIT2 alters hypothalamic transcriptomic signatures related to diabetes and metabolic pathways. Deletion of GIT2 reduced whole animal respiratory exchange ratios away from those related to primary glucose usage for energy homeostasis. GIT2 knockout (GIT2KO mice demonstrated lower insulin secretion levels, disruption of pancreatic islet beta cell mass, elevated plasma glucose and insulin resistance. High-dimensionality transcriptomic signatures from islets isolated from GIT2KO mice indicated a disruption of beta cell development. Additionally, GIT2 expression was prematurely elevated in pancreatic and hypothalamic tissues from diabetic-state mice (db/db, compared to age-matched wild type controls, further supporting the role of GIT2 in metabolic regulation and aging. We also found that the physical interaction of pancreatic GIT2 with the insulin receptor and insulin receptor substrate 2 was diminished in db/db mice compared to wild type mice. Therefore GIT2 appears to exert a multidimensional ‘keystone’ role in regulating the aging process by coordinating somatic responses to energy deficits.

  17. Application of the Commission’s recommendations: the activities of ICRP Committee 4

    International Nuclear Information System (INIS)

    Lochard, Jacques

    2012-01-01

    Committee 4 of the International Commission on Radiological Protection (ICRP) is responsible for developing principles, recommendations, and guidance on the protection of man against radiation exposure; and considering their practical application in all exposure situations. The Committee also acts as a major point of contact between ICRP and other international organisations and professional bodies concerned with protection against ionising radiation. The current work of the Committee involves the development of a series of reports on implementation of the 2007 Recommendations, and a reflection on the ethical foundations of the radiological protection system. Following the accident in Fukushima, Committee 4 also initiated an analysis of management of the consequences of the accident, with the objective of revising, if necessary, the Commission’s publications on emergency and post-accident situations.

  18. Flying Real-Time Network to Coordinate Disaster Relief Activities in Urban Areas

    Directory of Open Access Journals (Sweden)

    Matias Micheletto

    2018-05-01

    Full Text Available While there have been important advances within wireless communication technology, the provision of communication support during disaster relief activities remains an open issue. The literature in disaster research reports several major restrictions to conducting first response activities in urban areas, given the limitations of telephone networks and radio systems to provide digital communication in the field. In search-and-rescue operations, the communication requirements are increased, since the first responders need to rely on real-time and reliable communication to perform their activities and coordinate their efforts with other teams. Therefore, these limitations open the door to improvisation during disaster relief efforts. In this paper, we argue that flying ad-hoc networks can provide the communication support needed in these scenarios, and propose a new solution towards that goal. The proposal involves the use of flying witness units, implemented using drones, that act as communication gateways between first responders working at different locations of the affected area. The proposal is named the Flying Real-Time Network, and its feasibility to provide communication in a disaster scenario is shown by presenting both a real-time schedulability analysis of message delivery, as well as simulations of the communication support in a physical scenario inspired by a real incident. The obtained results were highly positive and consistent, therefore this proposal represents a step forward towards the solution of this open issue.

  19. Flying Real-Time Network to Coordinate Disaster Relief Activities in Urban Areas †

    Science.gov (United States)

    Micheletto, Matias; Orozco, Javier; Mosse, Daniel

    2018-01-01

    While there have been important advances within wireless communication technology, the provision of communication support during disaster relief activities remains an open issue. The literature in disaster research reports several major restrictions to conducting first response activities in urban areas, given the limitations of telephone networks and radio systems to provide digital communication in the field. In search-and-rescue operations, the communication requirements are increased, since the first responders need to rely on real-time and reliable communication to perform their activities and coordinate their efforts with other teams. Therefore, these limitations open the door to improvisation during disaster relief efforts. In this paper, we argue that flying ad-hoc networks can provide the communication support needed in these scenarios, and propose a new solution towards that goal. The proposal involves the use of flying witness units, implemented using drones, that act as communication gateways between first responders working at different locations of the affected area. The proposal is named the Flying Real-Time Network, and its feasibility to provide communication in a disaster scenario is shown by presenting both a real-time schedulability analysis of message delivery, as well as simulations of the communication support in a physical scenario inspired by a real incident. The obtained results were highly positive and consistent, therefore this proposal represents a step forward towards the solution of this open issue. PMID:29789458

  20. Supervision and technical coordination of the German activities in the 2D/3D-project

    International Nuclear Information System (INIS)

    Mayinger, F.

    1988-01-01

    The German Federal Minister for Research and Technology, the Japanese Atomic Energy Bureau, represented by the Japan Atomic Energy Research Institute (JAERI) and the United States Nuclear Regulatory Commission (USNRC) made a contract to cooperate in the field of nuclear safety research with the aim to improve and to guarantee the safety of water-cooled nuclear reactors on an international basis by joint research activities in the 2D/3D-project. The necessity for these research activities results from gaps in the status of knowledge for a best-estimate analysis in emergency core cooling, from the legally established duty to minimize the radioactive emission to the environment as consequence of an incident, and from the effort to optimize the safeguard systems of nuclear reactors continuously and steadily. The activities which were performed in the frame of this project concentrated on the coordination of the experimental and theoretical work, as well as on the technical supervision with respect to an efficient attainment of the internationally aspired research aim and to an optimal adjustment with respect to the emergency core cooling problems of pressurized water reactors. (orig.) [de

  1. Dopamine D1 receptor activation maintains motor coordination in injured rats but does not accelerate the recovery of the motor coordination deficit.

    Science.gov (United States)

    Avila-Luna, Alberto; Gálvez-Rosas, Arturo; Alfaro-Rodríguez, Alfonso; Reyes-Legorreta, Celia; Garza-Montaño, Paloma; González-Piña, Rigoberto; Bueno-Nava, Antonio

    2018-01-15

    The sensorimotor cortex and the striatum are interconnected by the corticostriatal pathway, suggesting that cortical injury alters the striatal function that is associated with skilled movements and motor learning, which are functions that may be modulated by dopamine (DA). In this study, we explored motor coordination and balance in order to investigate whether the activation of D 1 receptors (D 1 Rs) modulates functional recovery after cortical injury. The results of the beam-walking test showed motor deficit in the injured group at 24, 48 and 96h post-injury, and the recovery time was observed at 192h after cortical injury. In the sham and injured rats, systemic administration of the D 1 R antagonist SCH-23390 (1mg/kg) alone at 24, 48, 96 and 192h significantly (Pmotor deficit, while administration of the D 1 R agonist SKF-38393 alone (2, 3 and 4mg/kg) at 24, 48, 96 and 192h post-injury did not produce a significant difference; however, the co-administration of SKF-38393 and SCH-23390 prevented the antagonist-induced increase in the motor deficit. The cortical+striatal injury showed significantly increased the motor deficit at 24, 48, 96 and 192h post-injury (Pmotor recovery, but the activation of D 1 Rs maintained motor coordination, confirming that an intact striatum may be necessary for achieving recovery. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Eurocan plus report: feasibility study for coordination of national cancer research activities.

    Science.gov (United States)

    2008-01-01

    The EUROCAN+PLUS Project, called for by the European Parliament, was launched in October 2005 as a feasibility study for coordination of national cancer research activities in Europe. Over the course of the next two years, the Project process organized over 60 large meetings and countless smaller meetings that gathered in total over a thousand people, the largest Europe-wide consultation ever conducted in the field of cancer research.Despite a strong tradition in biomedical science in Europe, fragmentation and lack of sustainability remain formidable challenges for implementing innovative cancer research and cancer care improvement. There is an enormous duplication of research effort in the Member States, which wastes time, wastes money and severely limits the total intellectual concentration on the wide cancer problem. There is a striking lack of communication between some of the biggest actors on the European scene, and there are palpable tensions between funders and those researchers seeking funds.It is essential to include the patients' voice in the establishment of priority areas in cancer research at the present time. The necessity to have dialogue between funders and scientists to establish the best mechanisms to meet the needs of the entire community is evident. A top priority should be the development of translational research (in its widest form), leading to the development of effective and innovative cancer treatments and preventive strategies. Translational research ranges from bench-to-bedside innovative cancer therapies and extends to include bringing about changes in population behaviours when a risk factor is established.The EUROCAN+PLUS Project recommends the creation of a small, permanent and independent European Cancer Initiative (ECI). This should be a model structure and was widely supported at both General Assemblies of the project. The ECI should assume responsibility for stimulating innovative cancer research and facilitating processes

  3. Focus on the Activity of a Local Ethics Committee in Italy

    Directory of Open Access Journals (Sweden)

    Pamela Barbadoro

    2008-06-01

    Full Text Available

    Background: The continuing evolution of medical treatments and the loss of neutrality of medicine with respect to morality of human values have represented the major tracking elements towards settings of sharing of choices between society and medicine. Several concerns have been raised upon links between pharmaceutical corporations and researchers. Moreover, being in a learning environment, we must pay even more attention to these items because students appear to be at risk for unrecognized influence by marketing efforts. The aim of this study is to focus on the activities of a local ethics committee (LEC and the characteristics of the protocols discussed in an Italian LEC during a three year period (2001-2003.

    Methods: Three years of activity of a LEC were analysed by a questionnaire registering: main sponsorship, setting, technical characteristics of trials, outcome of the submission to the LEC, state of progress. Approved trials were followed-up until April 30th, 2005.

    Results: A total of 345 protocols were discussed. 67.8% (n = 198 of approved protocols were submitted by a pharmaceutical corporation. 72.6% (n = 212 of studies approved in 2001 were still in progress in 2005. 91.3% (n = 73 of closed trials had a pharmaceutical corporation as their main sponsor. None of the submitted studies focused on prevention strategies.

    Conclusions: These results show how important grants offered by pharmaceutical industries are, the efforts spent on therapy and the lack of investors in prevention.

  4. Relationships between levels of motor coordination, attention and physical activity in children: The mediation model

    Directory of Open Access Journals (Sweden)

    Jakub Kokštejn

    2012-12-01

    Full Text Available BACKGROUND: Current findings suggest that physical activity of children with developmental difficulties may be limited by low level of motor coordination. Motor difficulties are often connected with children suffering from attention deficit disorder. OBJECTIVE: The aim of the study was to find out the level of physical activity (PA in older school-age children with motor difficulties (MD in comparison with children without MD and to reveal possible mediate impact on attention between the level of motor skills and PA in children of this age. METHODS: Participants were divided into two groups: 15 children with MD (age 13.7 ± 1.6 years and 27 children without MD (age 13.3 ± 1.4 years. Motor functions were assessed by means of test battery MABC-2, weekly physical activity by means of Actigraph accelerometer and attention by both d2 and numeric square tests. To estimate the mediation of the attention level we have used Baron's & Kenny's (1986 analysis. RESULTS: In most of the indicators of PA, children with MD reached lower value than those without MD. The differences of statistical significance were found in the number of steps per week and weekdays (d = 0.50 and 0.64 respectively and in PA of a very high intensity (d =2 .00 in boys with and without MD. In girls with MD we have found out significantly less time spent in vigorous intensity PA (d = 0.86. The study results support the hypothesis of developmental motor deficits to be a risk factor for PA in older school-age children. Significant mediation effect of concentration of attention in the relationship between the level of motor skills and PA was observed in three cases - in the relationship between gross motor skills on the one hand, and energy expenditure per week and weekdays, and vigorous intensity PA per week on the other. The amount of mediation effect of attention concentration ranged between 12-22%. CONCLUSION: The study has indicated that children's participation in PA can be

  5. Information on Nea programmes on nuclear energy and civil society and their co-ordination

    International Nuclear Information System (INIS)

    Mays, C.; Riotte, H.

    2004-01-01

    At its session in May 2002, the Steering Committee for Nuclear Energy welcomed the activities that the NEA standing technical committees were carrying out in the field of nuclear energy and civil society, and agreed on the value of existing co-ordination among them. Tile Committee asked the Secretariat to prepare an information document on such co-ordination activities. With this in mind, the present room document offers an up-to-date account of relevant NEA activities and their co-ordination, pending a broader review of NEA's involvement in the area of nuclear energy and civil society, in the context of the NEA Strategic Plan at an appropriate time. (author)

  6. French National Alliance for Energy Research Coordination - Ancre, Activity Report 2015-2016

    International Nuclear Information System (INIS)

    Alazard-Toux, Nathalie; Allard, Francis; Becue, Thierry; Bernard, Herve; Bourgoin, Jean-Philippe; Brault, Pascal; Carre, Franck; Chabrelie, Marie-Francoise; Charrue, Herve; Colonna, Paul; Compere, Chantal; Criqui, Patrick; David, Sylvain; Devezeaux, Jean-Guy; Dollet, Alain; Duplan, Jean-Luc; Fabre, Francoise; Ferrant, Pierre; Flamant, Gilles; Forti, Laurent; Gentier, Sylvie; Gouy, Jean-Philippe; Hadj-Said, Nouredine; Lacour, Jean-Jacques; Latroche, Michel; Legrand, Jack; Lemoine, Fabrice; Le Net, Elisabeth; Le Thiez, Pierre; Lhomme-Maublanc, Julie; Lucchese, Paul; Malbranche, Philippe; Mermilliod, Nicole; Most, Jean-Michel; Rondot, Yolande; Tilagone, Richard; Touboul, Francoise; Uster, Guillaume; Vidal, Olivier

    2017-01-01

    Created on 17 July 2009, ANCRE (French National Alliance for Energy Research Coordination) brings together 19 research and innovation bodies and higher education institution consortia in the field of energy. Its missions, carried out in liaison with competitiveness clusters and funding agencies, are to: - reinforce synergies and partnerships between research bodies, universities and companies, - identify scientific and technical challenges hampering industrial development, - propose research and innovation programs and approaches to their implementation, - contribute to the development of national research strategy in the field of energy, as well as funding agency program development. Its 2 main societal challenges are: Clean, secure and efficient energy, and Sustainable mobility and urban systems. ANCRE mobilizes 200 scientists involved in 10 programmatic groups (1 - Energy from biomass, 2 - Fossil energy, geothermal energy, critical metals, 3 - Nuclear energy, 4 - Solar energy, 5 - Ocean, hydraulic and wind energy, 6 - Transport, 7 - Buildings, 8 - Industries and agriculture, 9 - Energy forecasting and economics, 10 - Energy networks and associated storage) and 2 cross-disciplinary groups (Strategy, Europe and international). This activity report presents the ANCRE's 2015-2016 Highlights, its future challenges, its contribution to public policy-making, its close cooperation with the French national research agency and active participation in European programs, its mobilizing, structuring and uniting communities, and its knowledge production and dissemination

  7. Phase Coordinate System and p-q Theory Based Methods in Active Filtering Implementation

    Directory of Open Access Journals (Sweden)

    POPESCU, M.

    2013-02-01

    Full Text Available This paper is oriented towards implementation of the main theories of powers in the compensating current generation stage of a three-phase three-wire shunt active power system. The system control is achieved through a dSPACE 1103 platform which is programmed under the Matlab/Simulink environment. Four calculation blocks included in a specifically designed Simulink library are successively implemented in the experimental setup. The first two approaches, namely those based on the Fryze-Buchholz-Depenbrock theory and the generalized instantaneous reactive power theory, make use of phase quantities without any transformation of the coordinate system and provide the basis for calculating the compensating current when total compensation is desired. The others are based on the p-q theory concepts and require the direct and reverse transformation to/from the two-phases stationary reference frame. They are used for total compensation and partial compensation of the current harmonic distortion. The experimental results, in terms of active filtering performances, validate the control strategies implementation and provide arguments in choosing the most appropriate method.

  8. Coordination of deep hip muscle activity is altered in symptomatic femoroacetabular impingement.

    Science.gov (United States)

    Diamond, Laura E; Van den Hoorn, Wolbert; Bennell, Kim L; Wrigley, Tim V; Hinman, Rana S; O'Donnell, John; Hodges, Paul W

    2017-07-01

    Diagnosis of femoroacetabular impingement (FAI) is increasing, yet the associated physical impairments remain poorly defined. This morphological hip condition can cause joint pain, stiffness, impaired function, and eventually hip osteoarthritis. This exploratory study compared coordination of deep hip muscles between people with and without symptomatic FAI using analysis of muscle synergies (i.e., patterns of activity of groups of muscles activated in synchrony) during gait. Fifteen individuals (11 males) with symptomatic FAI (clinical examination and imaging) and 14 age- and sex-comparable controls without morphological FAI underwent testing. Intramuscular fine-wire and surface electrodes recorded electromyographic activity of selected deep and superficial hip muscles. A non-negative matrix factorization algorithm extracted three synergies which were compared between groups. Information regarding which muscles were activated together in the FAI group (FAI group synergy vector) was used to reconstruct individual electromyography patterns and compare groups. Variance accounted for (VAF) by three synergies was less for the control (94.8 [1.4]%) than FAI (96.0 [1.0]%) group (p = 0.03). VAF of obturator internus was significantly higher in the FAI group (p = 0.02). VAF of the reconstructed individual electromyography patterns with the FAI or control group vector were significantly higher for the FAI group (p hip muscles in the synergy related to hip joint control during early swing differed between groups. This phase involves movement towards the impingement position, which has relevance for the interpretation of synergy differences and potential clinical importance. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1494-1504, 2017. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  9. Distinct Temporal Coordination of Spontaneous Population Activity between Basal Forebrain and Auditory Cortex

    Directory of Open Access Journals (Sweden)

    Josue G. Yague

    2017-09-01

    Full Text Available The basal forebrain (BF has long been implicated in attention, learning and memory, and recent studies have established a causal relationship between artificial BF activation and arousal. However, neural ensemble dynamics in the BF still remains unclear. Here, recording neural population activity in the BF and comparing it with simultaneously recorded cortical population under both anesthetized and unanesthetized conditions, we investigate the difference in the structure of spontaneous population activity between the BF and the auditory cortex (AC in mice. The AC neuronal population show a skewed spike rate distribution, a higher proportion of short (≤80 ms inter-spike intervals (ISIs and a rich repertoire of rhythmic firing across frequencies. Although the distribution of spontaneous firing rate in the BF is also skewed, a proportion of short ISIs can be explained by a Poisson model at short time scales (≤20 ms and spike count correlations are lower compared to AC cells, with optogenetically identified cholinergic cell pairs showing exceptionally higher correlations. Furthermore, a smaller fraction of BF neurons shows spike-field entrainment across frequencies: a subset of BF neurons fire rhythmically at slow (≤6 Hz frequencies, with varied phase preferences to ongoing field potentials, in contrast to a consistent phase preference of AC populations. Firing of these slow rhythmic BF cells is correlated to a greater degree than other rhythmic BF cell pairs. Overall, the fundamental difference in the structure of population activity between the AC and BF is their temporal coordination, in particular their operational timescales. These results suggest that BF neurons slowly modulate downstream populations whereas cortical circuits transmit signals on multiple timescales. Thus, the characterization of the neural ensemble dynamics in the BF provides further insight into the neural mechanisms, by which brain states are regulated.

  10. Mannitol transport and mannitol dehydrogenase activities are coordinated in Olea europaea under salt and osmotic stresses.

    Science.gov (United States)

    Conde, Artur; Silva, Paulo; Agasse, Alice; Conde, Carlos; Gerós, Hernâni

    2011-10-01

    The intracellular accumulation of organic compatible solutes functioning as osmoprotectants, such as polyols, is an important response mechanism of several plants to drought and salinity. In Olea europaea a mannitol transport system (OeMaT1) was previously characterized as a key player in plant response to salinity. In the present study, heterotrophic sink models, such as olive cell suspensions and fruit tissues, and source leaves were used for analytical, biochemical and molecular studies. The kinetic parameters of mannitol dehydrogenase (MTD) determined in cells growing in mannitol, at 25°C and pH 9.0, were as follows: K(m), 54.5 mM mannitol; and V(max), 0.47 μmol h⁻¹ mg⁻¹ protein. The corresponding cDNA was cloned and named OeMTD1. OeMTD1 expression was correlated with MTD activity, OeMaT1 expression and carrier-mediated mannitol transport in mannitol- and sucrose-grown cells. Furthermore, sucrose-grown cells displayed only residual OeMTD activity, even though high levels of OeMTD1 transcription were observed. There is evidence that OeMTD is regulated at both transcriptional and post-transcriptional levels. MTD activity and OeMTD1 expression were repressed after Na+, K+ and polyethylene glycol (PEG) treatments, in both mannitol- and sucrose-grown cells. In contrast, salt and drought significantly increased mannitol transport activity and OeMaT1 expression. Taken together, these studies support that olive trees cope with salinity and drought by coordinating mannitol transport with intracellular metabolism.

  11. French butane propane committee. 2004 activity report; Comite francais du butane et du propane. Rapport d'activite 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This activity report presents the French butane-propane committee (CFBP), an association for the promotion of liquefied petroleum gases (LPG), the characteristics of LPG fuels, the LPG market and its evolution, the CFBP's missions and the 2004 highlights: representation of subscribing companies, participation to standardization works, making techniques and regulations change, improving the safety of equipments and installations, training and information, promoting LPG products. (J.S.)

  12. French butane propane committee. 2003 activity report; Comite francais du butane et du propane. Rapport d'activite 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This activity report presents the French butane-propane committee (CFBP), an association for the promotion of liquefied petroleum gases (LPG), the characteristics of LPG fuels, the LPG market and its evolution, the CFBP's missions and the 2003 highlights: representation of subscribing companies, participation to standardization works, making techniques and regulations change, improving the safety of equipments and installations, training and information, promoting LPG products. (J.S.)

  13. Ian Taylor MBE MP Chairman Parliamentary and Scientific Committee, United Kingdom (second from left) with (from left to right) CMS Technical Coordinator A. Ball, CMS Spokesperson Tejinder (Jim) Virdee and Adviser to the Director-General J. Ellis on 2 November 2009.

    CERN Multimedia

    Maximilien Brice; CMS

    2009-01-01

    Ian Taylor MBE MP Chairman Parliamentary and Scientific Committee, United Kingdom (second from left) with (from left to right) CMS Technical Coordinator A. Ball, CMS Spokesperson Tejinder (Jim) Virdee and Adviser to the Director-General J. Ellis on 2 November 2009.

  14. Foreign trip report: International Nuclide Transport Code Intercomparison Study (INTRACOIN) workshop and coordinating committee meeting, Interlaken, Switzerland, February 15-20, 1982

    International Nuclear Information System (INIS)

    Jansen, G. Jr.; Hewitt, W.M.

    1986-01-01

    The INTRACOIN (International Nuclide TRAnsport COde INtercomparison study) workshop provided material with which to benchmark codes and demonstrated a wide variety of capabilities for several types of transport problems in radionuclide migrations. Review lectures pointed to the general methods for solving ground-water transport problems and the difficulties to be expected in applying them to performance assessment. Numerical examples of solutions to benchmark problems important in waste repository safety assessment were presented. A framework of solved analytical models was provided by the work of Dr. Thomas H. Pigford of the University of California, Berkeley. Results from the US Department of Energy (DOE)-sponsored participants showed that the analytical codes are working properly and give results comparable to those of others. Further analysis of the results is needed to pinpoint discrepancies and resolve conflicts in boundary assumptions. In the coordinating group meeting, plans were made to complete a Level 1 report, and three problems with field test pumping data were fully defined and agreed upon for Level 2. The Office of Nuclear Waste Isolation (ONWT) agreed to host the Level 2 workshop in November 1982 and to appoint technical advisors to the Level 3 technical subcommittee of the coordinating group. Some information is included in microfiche form only. 8 refs., 11 tabs

  15. Joint Coordination and Muscle Activities of Ballet Dancers During Tiptoe Standing.

    Science.gov (United States)

    Tanabe, Hiroko; Fujii, Keisuke; Kouzaki, Motoki

    2017-01-01

    We aimed to investigate joint coordination of lower limbs in dancers during tiptoe standing and the relationship between joint coordination and muscle coactivation. Seven female ballet dancers performed tiptoe standing with six leg positions (fi e classical dance positions and one modern dance position) for 10 s. The kinematic data of the metatarsophalangeal (MP), ankle, knee, and hip joints was collected, and surface electromyography (EMG) of over 13 lower limb muscles was conducted. Principal component analysis was performed to determine joint coordination. MP-ankle and ankle-knee had in-phase coordination, whereas knee-hip showed anti-phase coordination in the sagittal plane. In addition, most EMG-EMG coherence around the MP and ankle joints was significant up to 50 Hz when these two joints swayed with in-phase. This suggests that different joint coordination patterns are associated with neural processing related to different muscle coactivation patterns. In conclusion, ballet dancers showed in-phase coordination from the MP to knee joints, which was associated with muscle coactivation to a higher frequency domain (up to 50 Hz) in comparison with anti-phase coordination.

  16. The European radioecology alliance: encouraging the coordination and integration of research activities in radioecology

    Energy Technology Data Exchange (ETDEWEB)

    Real, A. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas - CIEMAT (Spain); European Radioecology Alliance Association, French Institute for Radiological Protection and Nuclear Safety - IRSN, 31 Avenue de la Division Leclerc, BP 17, 92262 Fontenay-aux-Roses Cedex (France); Currivan, Lorraine [Radiological Protection Institute of Ireland - RPII (Ireland); Gariel, Jean-Christophe [Institut de Radioprotection et de Surete Nucleaire - IRSN (France); Hardeman, Frank [SCK.CEN (Belgium); Howard, Brenda [Natural Environment Research Council - NERC, UK (United Kingdom); Lukashenko, Sergey [Kazakhstan Republic Institute of Nuclear Physics - NNCRK (Kazakhstan); Lund, Ingemar [Swedish Radiation Safety Authority - SSM (Sweden); Sabatier, Laure [Commissariat a l' energie atomique et aux energies alternatives - CEA (France); Sachs, Susanne [Helmholtz-Zentrum Dresden-Rossendorf - HZDR (Germany); Salomaa, Sisko [Radiation and Nuclear Safety Authority - STUK (Finland); Smith, James [University of Portsmouth - UoP (United Kingdom); Steiner, Martin [Federal Office for Radiation Protection - BfS (Germany); Strand, Per [Norwegian Radiation Protection Authority - NRPA (Norway); Tschiersch, Jochen [Helmholtz Zentrum Muenchen - HMGU (Germany); Hinton, Thomas [Strategy for Allied Radioecology - STAR Coordinator, IRSN (France); Vandenhove, Hildegarde [COordination and iMplementation of a pan-European instrumenT for radioecology - COMET Coordinator, SCK.CEN (Belgium)

    2014-07-01

    The European Radioecology Alliance was established in 2009 with a firm conviction from its eight founding European organizations that joining forces would enhance the competence of radioecology science in Europe. The main objective of the Radioecology Alliance is to progressively strengthen the coordination and integration of research in the field of radioecology at national, European and international level. The integration of the European radioecology community will be a key aspect facing the upcoming EURATOM Horizon 2020 framework programme. In 2012, the Radioecology Alliance was officially constituted as an Association, and in June 2013 grew from 8 to 14 members from 10 different countries (Belgium, Finland, France, Germany, Ireland, Kazakhstan, Norway, Spain, Sweden and United Kingdom). Within the framework of the Radioecology Alliance, a Network of Excellence in Radioecology STAR (Strategy for Allied Radioecology) was created in 2011 with financial support of the EC FP7. More recently, the project COMET (Coordination and implementation of a pan-European instrument for radioecology) has been also funded by the EC to strengthen the pan-European research initiative on the radiation impact on man and the environment by facilitating the integration of the Research and Development activities in radioecology. The Radioecology Alliance, in close collaboration with STAR in the first phase, and more recently with COMET, has developed for the first time a Strategic Research Agenda (SRA) on Radioecology. The SRA identifies three challenges: (1) To predict human and wildlife exposure more robustly by quantifying the key processes that most influence radionuclide transfers; (2) To determine ecological consequences under realistic exposure conditions and (3) To improve human and environmental protection by integrating radioecology. Within these 3 challenges, 15 research lines have been identified. After a consultation process which included not only the scientific community

  17. A practical approach for active camera coordination based on a fusion-driven multi-agent system

    Science.gov (United States)

    Bustamante, Alvaro Luis; Molina, José M.; Patricio, Miguel A.

    2014-04-01

    In this paper, we propose a multi-agent system architecture to manage spatially distributed active (or pan-tilt-zoom) cameras. Traditional video surveillance algorithms are of no use for active cameras, and we have to look at different approaches. Such multi-sensor surveillance systems have to be designed to solve two related problems: data fusion and coordinated sensor-task management. Generally, architectures proposed for the coordinated operation of multiple cameras are based on the centralisation of management decisions at the fusion centre. However, the existence of intelligent sensors capable of decision making brings with it the possibility of conceiving alternative decentralised architectures. This problem is approached by means of a MAS, integrating data fusion as an integral part of the architecture for distributed coordination purposes. This paper presents the MAS architecture and system agents.

  18. Committee-Based Active Learning for Surrogate-Assisted Particle Swarm Optimization of Expensive Problems.

    Science.gov (United States)

    Wang, Handing; Jin, Yaochu; Doherty, John

    2017-09-01

    Function evaluations (FEs) of many real-world optimization problems are time or resource consuming, posing a serious challenge to the application of evolutionary algorithms (EAs) to solve these problems. To address this challenge, the research on surrogate-assisted EAs has attracted increasing attention from both academia and industry over the past decades. However, most existing surrogate-assisted EAs (SAEAs) either still require thousands of expensive FEs to obtain acceptable solutions, or are only applied to very low-dimensional problems. In this paper, a novel surrogate-assisted particle swarm optimization (PSO) inspired from committee-based active learning (CAL) is proposed. In the proposed algorithm, a global model management strategy inspired from CAL is developed, which searches for the best and most uncertain solutions according to a surrogate ensemble using a PSO algorithm and evaluates these solutions using the expensive objective function. In addition, a local surrogate model is built around the best solution obtained so far. Then, a PSO algorithm searches on the local surrogate to find its optimum and evaluates it. The evolutionary search using the global model management strategy switches to the local search once no further improvement can be observed, and vice versa. This iterative search process continues until the computational budget is exhausted. Experimental results comparing the proposed algorithm with a few state-of-the-art SAEAs on both benchmark problems up to 30 decision variables as well as an airfoil design problem demonstrate that the proposed algorithm is able to achieve better or competitive solutions with a limited budget of hundreds of exact FEs.

  19. Developmental coordination disorder, generalized self-efficacy toward physical activity, and participation in organized and free play activities.

    Science.gov (United States)

    Cairney, John; Hay, John A; Faught, Brent E; Wade, Terrance J; Corna, Laurie; Flouris, Andreas

    2005-10-01

    To test a theoretical model linking developmental coordination disorder (DCD) to reduced physical activity (PA) through the mediating influence of generalized self-efficacy regarding PA. This was a cross-sectional investigation of students in grades 4 through 8 from 5 elementary schools in the Niagara region of Ontario, Canada (n=590). Motor proficiency was evaluated using the short-form Bruininks-Oseretsky Test of Motor Proficiency. Generalized self-efficacy was assessed using the Children's Self-Perceptions of Adequacy in and Predilection for Physical Activity scale, and PA levels were evaluated using a 61-item Participation Questionnaire. Structural equation modeling was used to test the influence of generalized self-efficacy on the relationship between DCD and PA. In this sample, 7.5% (n=44) of the children met the requirements for probable DCD. The effect of DCD on PA was mediated by generalized self-efficacy. In this model, 28% of the variance in children's PA was predicted by generalized self-efficacy and DCD. Our results suggest that children with DCD are less likely to be physically active and that generalized self-efficacy can account for a considerable proportion of this relationship. The implications for appropriate interventions to increase PA among children with DCD are discussed.

  20. Co-ordinated Research Projects (CRPs): Annual report of activities and statistics for 2002

    International Nuclear Information System (INIS)

    2003-08-01

    and technical publications (TECDOCs). In certain cases the research results are directly relevant to implementation of projects in the Agency's Technical Co-operation Programme. In terms of number of awards and degree of funding, CRPs constitute a significant activity within the Agency's programmes. 1003 contracts and agreements were awarded from the 1364 contract and agreement proposals received by the Agency during 2002. Annex I lists by country the number of proposals received and awards made. In 2002, $6 329 221 were awarded from the regular budget to institutes under contractual arrangements and to fund Research Co-ordination Meetings (RCMs). Additionally, $122 077 of extra-budgetary contributions was used to fund additional contracts and RCMs. Thus, total awards amounted to $6 451 298. Table 1 summarizes all awards by Programme in 2002. The average award per contract was $5 700

  1. Co-ordinated Research Projects (CRPs): Annual report of activities and statistics for 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-08-15

    and technical publications (TECDOCs). In certain cases the research results are directly relevant to implementation of projects in the Agency's Technical Co-operation Programme. In terms of number of awards and degree of funding, CRPs constitute a significant activity within the Agency's programmes. 1003 contracts and agreements were awarded from the 1364 contract and agreement proposals received by the Agency during 2002. Annex I lists by country the number of proposals received and awards made. In 2002, $6 329 221 were awarded from the regular budget to institutes under contractual arrangements and to fund Research Co-ordination Meetings (RCMs). Additionally, $122 077 of extra-budgetary contributions was used to fund additional contracts and RCMs. Thus, total awards amounted to $6 451 298. Table 1 summarizes all awards by Programme in 2002. The average award per contract was $5 700.

  2. 20 CFR 641.335 - How should the Governor address the coordination of SCSEP services with activities funded under...

    Science.gov (United States)

    2010-04-01

    ... COMMUNITY SERVICE EMPLOYMENT PROGRAM The State Senior Employment Services Coordination Plan § 641.335 How... Agencies on Aging in the State and the State and Local Boards established under title I of WIA. (OAA sec... State Plan must describe the steps being taken to ensure that the SCSEP is an active partner in each One...

  3. Perceived athletic competence and physical activity in children with developmental coordination disorder who are clinically referred, and control children

    NARCIS (Netherlands)

    Noordstar, Johannes J.; Stuive, Ilse; Herweijer, Hester; Holty, Lian; Oudenampsen, Chantal; Schoemaker, Marina M.; Reinders-Messelink, Heleen A.

    2014-01-01

    The relationship between perceived athletic competence (PAC) and physical activity (PA) in children with developmental coordination disorder (DCD) is still unclear. This study investigated differences in PAC and PA between, and within, a group of children with DCD that were clinically referred (n =

  4. Co-ordination and methodological guidance of information activities in the Czechoslovak nuclear programme in building the branch information system

    International Nuclear Information System (INIS)

    Nejezchleb, V.

    1982-01-01

    The work of the control unit is described which secures the optimal operation of the system, its internal functions and its linkage with other systems. The aim of coordination and methodological activity is to strengthen working and organizational links within the framework of the construction and operation of sector information systems, the establishment of cooperation relations and the elimination of duplicity. (M.D.)

  5. Drug and Therapeutics (D & T) committees in Dutch hospitals : a nation-wide survey of structure, activities, and drug selection procedures

    NARCIS (Netherlands)

    Fijn, R; Brouwers, JRBJ; Knaap, RJ; De Jong-Van den Berg, LTW

    Aims To determine structure, activities and drug selection processes used by Dutch hospital drug and therapeutics (D & T) committees. Methods A pretested structured survey questionnaire based on the Australian process and impact indicators, previous research, and consultation of professionals was

  6. 5 CFR 591.241 - What are the key activities of the COLA Advisory Committees?

    Science.gov (United States)

    2010-01-01

    ... SERVICE REGULATIONS ALLOWANCES AND DIFFERENTIALS Cost-of-Living Allowance and Post Differential-Nonforeign...) The COLA Advisory Committees may— (1) Advise and assist OPM in planning living-cost surveys; (2) Provide or arrange for observers for data collection during living-cost surveys; (3) Advise and assist OPM...

  7. Report to NASA Committee on Aircraft Operating Problems Relative to Aviation Safety Engineering and Research Activities

    Science.gov (United States)

    1963-01-01

    The following report highlights some of the work accomplished by the Aviation Safety Engineering and Research Division of the Flight Safety Foundations since the last report to the NASA Committee on Aircraft Operating Problems on 22 May 1963. The information presented is in summary form. Additional details may be provided upon request of the reports themselves may be obtained from AvSER.

  8. Status of pseudo fission product cross sections for fast reactors. Results of the SWG 17, International working party on evaluation coordination of the nuclear science committee, NEA- OECD

    International Nuclear Information System (INIS)

    Gruppelaar, H.; Kloosterman, J.L.; Pijlgroms, B.J.; Rimpault, G.; Smith, P.; Ignatyuk, A.; Koshcheev, V.; Nikolaev, M.; Thsiboulia, A.; Kawai, M.; Nakagawa, T.; Watanabe, T.; Zukeran, A.; Nakajima, Y.; Matsunobu, H.

    1998-08-01

    Within the framework of the SWG17 benchmark organized by a Working Party of the Nuclear Science Committee of the Nuclear Energy Agency (NEA), a comparison of lumped or pseudo fission product cross sections for fast reactors has been made. Four institutions participated with data libraries based on the JEF2.2, EAF-4.2, BROND-2, FONDL-2.1, ADL-3 and JENDL-3.2 evaluated nuclear data files. Several parameters have been compared with each other: the one-group cross sections and reactivity worths of the lumped nuclide for several partial absorption and scattering cross sections, and the one-group cross sections of the individual fission products. Also graphs of the multi-group cross sections of the lumped nuclide have been compared, as well as graphs of capture cross sections for 27 nuclides. From two contributions based on JEF2.2, it can be concluded that the data processing influences the capture cross section by about 1% and the inelastic scattering cross section by 2%. The differences between the lumped cross sections of the different data libraries are surprisingly small: maximum 6% for capture and 9% for the inelastic scattering. Similar results are obtained for the reactivity effects. Since the reactivity worth of the lumped nuclide is dominated by the capture reaction, the maximum spread in the total reactivity worth is still only 5.3%. There is a systematic difference between total, elastic and capture cross sections of JENDL-3.2 and JEF2.2 of the same order of magnitude. Possible reasons for this discrepancy have been indicated. The one-group capture and inelastic scattering cross sections of most of the important individual fission products differ by less than 10% (root mean square values). Larger differences are observed for unstable nuclides where there is a lack of experimental data. For the (n,2n) group cross sections, which are rather sensitive to the weighting spectrum in the fast energy range, these differences are several tens of percents. The final

  9. Children with developmental coordination disorder play active virtual reality games differently than children with typical development.

    Science.gov (United States)

    Gonsalves, Leandra; Campbell, Amity; Jensen, Lynn; Straker, Leon

    2015-03-01

    Active virtual reality gaming (AVG) may be useful for children with developmental coordination disorder (DCD) to practice motor skills if their movement patterns are of good quality while engaged in AVG. This study aimed to examine: (1) the quality of motor patterns of children with DCD participating in AVG by comparing them with children with typical development (TD) and (2) whether differences existed in the motor patterns utilized with 2 AVG types: Sony PlayStation 3 Move and Microsoft Xbox 360 Kinect. This was a quasi-experimental, biomechanical laboratory-based study. Twenty-one children with DCD, aged 10 to 12 years, and 19 age- and sex-matched children with TD played a match of table tennis on each AVG type. Hand path, wrist angle, and elbow angle were recorded using a motion analysis system. Linear mixed-model analyses were used to determine differences between DCD and TD groups and Move and Kinect AVG type for forehands and backhands. Children with DCD utilized a slower hand path speed (backhand mean difference [MD]=1.20 m/s; 95% confidence interval [95% CI]=0.41, 1.98); greater wrist extension (forehand MD=34.3°; 95% CI=22.6, 47.0); and greater elbow flexion (forehand MD=22.3°; 95% CI=7.4, 37.1) compared with children with TD when engaged in AVG. There also were differences in movement patterns utilized between AVG types. Only simple kinematic measures were compared, and no data regarding movement outcome were assessed. If a therapeutic treatment goal is to promote movement quality in children with DCD, clinical judgment is required to select the most appropriate AVG type and determine whether movement quality is adequate for unsupervised practice. © 2015 American Physical Therapy Association.

  10. Study of the relationship between chemical structure and antimicrobial activity in a series of hydrazine-based coordination compounds.

    Science.gov (United States)

    Dobrova, B N; Dimoglo, A S; Chumakov, Y M

    2000-08-01

    The dependence of antimicrobial activity on the structure of compounds is studied in a series of compounds based on hydrazine coordinated with ions of Cu(II), Ni(II) and Pd(II). The study has been carried out by means of the original electron-topological method developed earlier. A molecular fragment has been found that is only characteristic of biologically active compounds. Its spatial and electron parameters have been used for the quantitative assessment of the activity in view. The results obtained can be used for the antimicrobial activity prediction in a series of compounds with similar structures.

  11. Identification of Residues in the Lipopolysaccharide ABC Transporter That Coordinate ATPase Activity with Extractor Function.

    Science.gov (United States)

    Simpson, Brent W; Owens, Tristan W; Orabella, Matthew J; Davis, Rebecca M; May, Janine M; Trauger, Sunia A; Kahne, Daniel; Ruiz, Natividad

    2016-10-18

    cytoplasmic membrane prior to transport to the cell surface. How ATP hydrolysis is coupled with LPS release from the membrane is not understood. We have identified residues at the interface between the ATPase and the transmembrane domains of this heteromeric ABC complex that are important for LPS transport, some of which coordinate ATPase activity with LPS release. Copyright © 2016 Simpson et al.

  12. Activities of special committee on 'quality assurance of accountancy analysis for safeguards'

    International Nuclear Information System (INIS)

    2010-01-01

    For the long-term stable operation of nuclear fuel cycle facilities, it is essential to satisfy the requirements of IAEA safeguards agreement. It could be attained by precise implementation of accountancy analysis of nuclear materials and application of Destructive Analysis (DA) which enables highly precise measurement is necessary. The requirements to maintain and improve the precision of DA are supposed to grow along with nuclear fuel cycle fully in progress and Pu handling amount increases. In order to maintain long-term stability of quality level of accountancy analysis for safeguards, a special committee on 'Quality Assurance (QA) for Accountancy /Safeguards analysis' was established at Atomic Energy Society Japan supported by INNM-Japan Chapter. Experts of safeguards analysis, reference materials, statistics and QA were gathered and drafted the committee standard document for isotope dilution mass spectrometry, the major accountancy analysis technique for Pu and U, supported Pu standard preparation at JAEA and summarized the items needed for QA of DA. (author)

  13. Redox-active porous coordination polymer based on trinuclear pivalate: Temperature-dependent crystal rearrangement and redox-behavior

    Energy Technology Data Exchange (ETDEWEB)

    Lytvynenko, Anton S. [L.V. Pisarzhevskii Institute of Physical Chemistry, National Academy of Sciences of Ukraine, Prospekt Nauki 31, Kiev 03028 (Ukraine); Kiskin, Mikhail A., E-mail: mkiskin@igic.ras.ru [N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninsky Prospect 31, GSP-1, 119991 Moscow (Russian Federation); Dorofeeva, Victoria N.; Mishura, Andrey M.; Titov, Vladimir E.; Kolotilov, Sergey V. [L.V. Pisarzhevskii Institute of Physical Chemistry, National Academy of Sciences of Ukraine, Prospekt Nauki 31, Kiev 03028 (Ukraine); Eremenko, Igor L.; Novotortsev, Vladimir M. [N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninsky Prospect 31, GSP-1, 119991 Moscow (Russian Federation)

    2015-03-15

    Linking of trinuclear pivalate Fe{sub 2}NiO(Piv){sub 6} (Piv=O{sub 2}CC(CH{sub 3}){sub 3}) by 2,6-bis(4-pyridyl)-4-(1-naphthyl)pyridine (L) resulted in formation of 1D-porous coordination polymer Fe{sub 2}NiO(Piv){sub 6}(L)·Solv, which was characterized in two forms: DMSO solvate Fe{sub 2}NiO(Piv){sub 6}(L)(DMSO)·2.5DMSO (1) or water solvate Fe{sub 2}NiO(Piv){sub 6}(L)(H{sub 2}O) (2). X-ray structure of 1 was determined. Crystal lattice of 1 at 160 K contained open channels, filled by captured solvent, while temperature growth to 296 K led to the crystal lattice rearrangement and formation of closed voids. Redox-behavior of 2 was studied by cyclic voltammetry for a solid compound, deposited on glassy-carbon electrode. Redox-activity of L preserved upon incorporation in the coordination polymer. The presence of pores in desolvated sample Fe{sub 2}NiO(Piv){sub 6}(L) was confirmed by the measurements of N{sub 2} and H{sub 2} adsorption at 77 K. Potential barriers of the different molecules diffusion through pores were estimated by the means of molecular mechanics. - Graphical abstract: Redox-behavior of 1D-porous coordination polymer Fe{sub 2}NiO(Piv){sub 6}(L)(H{sub 2}O) was studied by cyclic voltammetry in thin film, deposited on glassy-carbon electrode. Redox-activity of L preserved upon incorporation in the coordination polymer. Potential barriers of different molecules diffusion through pores were estimated by the means of molecular mechanics. - Highlights: • Porous 1D coordination polymer was synthesized. • Temperature growth led to pores closing due to crystal lattice rearrangement. • Redox-activity of ligand preserved upon incorporation into coordination polymer. • Redox-properties of solid coordination polymer were studied in thin film. • Diffusion barriers were evaluated by molecular mechanics.

  14. 77 FR 23250 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2012-04-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  15. 76 FR 25355 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2011-05-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  16. 78 FR 29134 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  17. French butane propane committee. 2003 activity report; Comite Francais du Butane et du Propane. Rapport d'activite 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-05-01

    This activity report presents the 2003 status of the actions carried out by the French butane and propane committee (CFBP) for the development of the liquefied petroleum gas (LPG) industry in France. While the past year has seen the butane, propane and LPG-fuel sales following the decay started 4 years ago, in 2004 the CFBP has reinforced its actions of public information about the LPG energy choice and has carried out several projects in order to improve the safety of LPG tanks and storage facilities, one of the first concern of LPG industry. (J.S.)

  18. AGU Committees

    Science.gov (United States)

    Administrative Committees are responsible for those functions required for the overall performance or well-being of AGU as an organization. These committees are Audit and Legal Affairs, Budget and Finance*, Development, Nominations*, Planning, Statutes and Bylaws*, Tellers.Operating Committees are responsible for the policy direction and operational oversight of AGU's primary programs. The Operating Committees are Education and Human Resources, Fellows*, Information Technology, International Participation*, Meetings, Public Affairs, Public Information, Publications*.

  19. Error correction in bimanual coordination benefits from bilateral muscle activity: evidence from kinesthetic tracking

    NARCIS (Netherlands)

    Ridderikhoff, A.; Peper, C.E.; Beek, P.J.

    2007-01-01

    Although previous studies indicated that the stability properties of interlimb coordination largely result from the integrated timing of efferent signals to both limbs, they also depend on afference-based interactions. In the present study, we examined contributions of afference-based error

  20. The distribution of cerebral activity related to visuomotor coordination indicating perceptual and executional specialization

    NARCIS (Netherlands)

    de Jong, BM; Frackowiak, RSJ; Willemsen, ATM; Paans, AMJ

    The distribution of increased regional cerebral blood flow (rCBF) related to visuomotor coordination was studied by means of positron emission tomography (PET) in normal subjects. An experimental condition, in which a vertically presented zigzag figure had to be copied in a horizontal orientation,

  1. Coordinated Active Power Dispatch for a Microgrid via Distributed Lambda Iteration

    DEFF Research Database (Denmark)

    Hu, Jianqiang; Z. Q. Chen, Michael; Cao, Jinde

    2017-01-01

    A novel distributed optimal dispatch algorithm is proposed for coordinating the operation of multiple micro units in a microgrid, which has incorporated the distributed consensus algorithm in multi-agent systems and the -iteration optimization algorithm in economic dispatch of power systems. Spec...

  2. Activation of a water molecule coordinated to manganese: four study cases

    International Nuclear Information System (INIS)

    Lassalle-Kaiser, B.

    2008-10-01

    The daunting energy consumption of western societies calls for the development of renewable energies. Among them, hydrogen stands as a major candidate. The cleanest way of producing hydrogen is water electro- or photolysis. This reaction is carried out in natural photosynthesis by a manganese-oxo cluster, the functioning of which remains unknown. Insight into this mechanism would greatly help the search for low-cost water splitting catalysts. Our contribution to this field is the understanding of the fundamental processes that govern the activation of water by manganese complexes. This manuscript describes our attempts to generate electrochemically mononuclear manganese(IV) complexes bearing a fully deprotonated water molecule (oxo ligand). We have studied four different cases, which reflect different possible coordination spheres capable of stabilizing such species. In the first chapter, we will give a brief overview of the present energetic challenges faced by western societies. In the second chapter, we will present general considerations about manganese chemistry and a description of the structure and functioning of the water oxidizing enzyme. We will also describe the basic requirements for the splitting of water and present the goals of our work. In the third chapter, we will present the synthesis of a new family of tetradentate ligands, together with the synthesis and full characterization of the corresponding nickel(II) complexes. The first results obtained with the manganese analogue will also be shown. Chapter four presents the formation and the full characterization of a mononuclear manganese(IV)-oxo complex, by electrochemical oxidation of a manganese(II)-aqua complex. We will present different pathways to generate this species and show which intermediates are involved in this 2 e - , 2 H + reaction. Chapter five describes the formation of a mononuclear manganese(IV) complex, by electrochemical oxidation of a manganese(III)-hydroxo complex. The

  3. 76 FR 33700 - Agricultural Policy Advisory Committee for Trade; Renewal

    Science.gov (United States)

    2011-06-09

    ...Pursuant to the Federal Advisory Committee Act, notice is hereby given that the Secretary of Agriculture (Secretary), in coordination with the United States Trade Representative (USTR), has renewed the Agricultural Policy Advisory Committee for Trade (APAC).

  4. Knee joint kinaesthesia and neuromuscular coordination during three phases of the menstrual cycle in moderately active women.

    Science.gov (United States)

    Fridén, Cecilia; Hirschberg, Angelica Lindén; Saartok, Tönu; Renström, Per

    2006-04-01

    An increased incidence of sports related injuries in the premenstrual phase as well as in the menstrual phase of the menstrual cycle has been described. This may be explained by alterations in proprioception and neuromuscular coordination due to hormonal variations. Prospective, within women analysis of knee joint kinesthesia and neuromuscular coordination were performed by repeated measures analysis of variance in three hormonally verified phases of three consecutive menstrual cycles. Thirty-two healthy, moderately active female subjects volunteered to participate in the study. Twenty-five of the subjects performed at least one hormonally verified menstrual cycle. A specially designed device was used to investigate knee joint kinaesthesia and neuromuscular coordination was measured with the square hop test. These tests were carried out in the menstrual phase, ovulation phase and premenstrual phase determined by hormone analyses in three consecutive menstrual cycles. An impaired knee joint kinaesthesia was detected in the premenstrual phase and the performance of square hop test was significantly improved in the ovulation phase compared to the other two phases. The results of this study indicate that the variation of sex hormones in the menstrual cycle has an effect on performance of knee joint kinaesthesia and neuromuscular coordination.

  5. SYNTHESIS, CHARACTERIZATION AND ANTITUMOR ACTIVITY OF A Ca (II COORDINATION POLYMER BASED ON 3-AMINO-2-PYRAZINECARBOXYLIC ACID

    Directory of Open Access Journals (Sweden)

    XI-SHI TAI

    2015-10-01

    Full Text Available A new Ca(II coordination polymer has been obtained by reaction of Ca(ClO42·H2O with 3-amino-2-pyrazinecarboxylic acid in CH3CH2OH/H2O. It was characterized by IR, 1HNMR, thermal analysis and X-ray single crystal diffraction analysis. X-ray analysis reveals that each Ca(II center is seven-coordination with a N2O5 distorted pentagonal bipyramidal coordination environment. The Ca(II ions are linked through the O atoms of 3-amino-2-pyrazinecarboxylic acid ligands to form 1D chain structure. And then a 3D network structure is constructed by hydrogen bonds and π-π stacking. The antitumor activity of 3-amino-2-pyrazinecarboxylic acid ligand and its Ca(II coordination polymer against human intestinal adenocarcinoma HCT-8 cells, lung adenocarcinoma HCT-116 cells and human lung adenocarcinoma A549 cells line have been investigated.

  6. Development of a database for prompt γ-ray neutron activation analysis: Summary report of the third research coordination meeting

    International Nuclear Information System (INIS)

    Lindstrom, Richard M.; Firestone, Richard B.; Paviotti-Corcuera, R.

    2003-01-01

    The main discussions and conclusions from the Third Co-ordination Meeting on the Development of a Database for Prompt Gamma-ray Neutron Activation Analysis are summarized in this report. All results were reviewed in detail, and the final version of the TECDOC and the corresponding software were agreed upon and approved for preparation. Actions were formulated with the aim of completing the final version of the TECDOC and associated software by May 2003

  7. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the second research coordination meeting

    International Nuclear Information System (INIS)

    Lone, M.A.; Mughabghab, S.F.; Paviotti-Corcuera, R.

    2001-06-01

    This report summarizes the presentations, recommendations and conclusions of the Second Research Co-ordination Meeting on Development of a Database for Prompt γ-ray Neutron Activation Analysis. The purpose of this meeting was to review results achieved on the development of the database, discuss further developments and planning of the products ol this CRP. Actions to be taken were agreed upon with the aim to complete the project by the end of 2002. (author)

  8. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the third research coordination meeting

    International Nuclear Information System (INIS)

    Lindstorm, Richard M.; Firestone, Richard B.; Paviotti-Corcuera, R.

    2003-04-01

    The main discussions and conclusions from the Third Co-ordination Meeting on the Development of a Database for Prompt γ-ray Neutron Activation Analysis are summarised in this report. All results were reviewed in detail, and the final version of the TECDOC and the corresponding software were agreed upon and approved for preparation. Actions were formulated with the aim of completing the final version of the TECDOC and associated software by May 2003. (author)

  9. Activities of RILEM Technical Committee: Internal Curing of Concrete and Anticipated Research

    DEFF Research Database (Denmark)

    Kovler, Konstantin; Jensen, Ole Mejlhede

    in the domain. To account for the different practices and different standards around the world, the TC included representatives from three different world regions: Europe, North America and Asia. Totally more than 30 members from 17 countries contributed in the committee work. Some of them serve in parallel...... of Concrete” of the International Union of Laboratories and Experts in Construction Materials, Systems and Structures (RILEM). The authors of this short communication served as a chair (K. Kovler) and secretary (O.M. Jensen) of the TC. The regular and corresponding members were acknowledged RILEM experts...

  10. Analysis of the sponsorship activities of the Organizing committee «Kiev City marathon – 2014»

    Directory of Open Access Journals (Sweden)

    Olena Yarmolyuk

    2015-04-01

    Full Text Available Purpose: to share the experience of the marketing technologies application in the physical culture and sports sphere and to improve the commercial activities of sports organizations during the planning and holding the mass sporting events. Material and Methods: the basic forms and methods of the sponsorship activities of the Organizing Committee of the competition «Kiev Marathon – 2014» were analyzed with system analysis, SWOT-analysis and sociological questioning (12 specialists from the Organizing Committee of «Kiev City Marathon – 2014» and 95 visitors of the «Kiev City Marathon – 2014» were questioned. Results: the best way for obtaining the sponsorship is to use the level-approach by the organizers, which means that all sponsors were divided on different levels and each one had certain privileges. It had resulted in appropriate sponsorship agreements. Conclusions: the results of research given in the article will enable professionals to most effectively search and work with the sponsors in the physical culture and sports sphere, as well as to introduce modern mechanisms of interaction between businesses and sporting organizations.

  11. Coordination activities of human planners during rescheduling: Case analysis and event handling procedure

    OpenAIRE

    2010-01-01

    Abstract This paper addresses the process of event handling and rescheduling in manufacturing practice. Firms are confronted with many diverse events, like new or changed orders, machine breakdowns, and material shortages. These events influence the feasibility and optimality of schedules, and thus induce rescheduling. In many manufacturing firms, schedules are created by several human planners. Coordination between them is needed to respond to events adequately. In this paper,...

  12. The Coordinating Laboratories for monitoring of environmental radioactivity. History, activities, perspectives

    International Nuclear Information System (INIS)

    Wiechen, A.; Bayer, A.

    2000-10-01

    The article reviews the development of the monitoring of environmental radioactivity in the former Federal Republic of Germany and from 1990 onwards in re-unified Germany. This monitoring originated in the need to investigate the radioactive fallout from the testing of atomic bombs in the atmosphere in the 1950's and 1960's. Monitoring was intensified and became increasingly regulated by law as a response to the large scale use of atomic power and in accordance with the Euratom Treaty of 1957. The necessity of evaluating the radiological effects in old mining regions in some of the new Laender was recognised in 1990. Since then legislation and official monitoring have been extended to include this source of radiation exposure. Also described is the way in which those institutions now termed Coordinating Laboratories were involved in all of the developments mentioned above. They tested and developed sampling, analysis and measurement techniques, carried out research projects on the various contamination pathways, reported regularly on environmental radioactivity and radiation exposure, organised and evaluated interlaboratory comparisons, assisted in the setting up of the Federal Integrated Measurement and Information System (IMIS), and advised the appropriate Federal and Laender Ministries. Some of the Coordinating Laboratories also manage Federal Monitoring Networks. The Precautionary Radiation Protection Act stipulates these tasks and names the institutions appointed as Coordinating Laboratories. (orig.) [de

  13. Coordinating Group report

    International Nuclear Information System (INIS)

    1994-01-01

    In December 1992, western governors and four federal agencies established a Federal Advisory Committee to Develop On-site Innovative Technologies for Environmental Restoration and Waste Management (the DOIT Committee). The purpose of the Committee is to advise the federal government on ways to improve waste cleanup technology development and the cleanup of federal sites in the West. The Committee directed in January 1993 that information be collected from a wide range of potential stakeholders and that innovative technology candidate projects be identified, organized, set in motion, and evaluated to test new partnerships, regulatory approaches, and technologies which will lead to improve site cleanup. Five working groups were organized, one to develop broad project selection and evaluation criteria and four to focus on specific contaminant problems. A Coordinating Group comprised of working group spokesmen and federal and state representatives, was set up to plan and organize the routine functioning of these working groups. The working groups were charged with defining particular contaminant problems; identifying shortcomings in technology development, stakeholder involvement, regulatory review, and commercialization which impede the resolution of these problems; and identifying candidate sites or technologies which could serve as regional innovative demonstration projects to test new approaches to overcome the shortcomings. This report from the Coordinating Group to the DOIT Committee highlights the key findings and opportunities uncovered by these fact-finding working groups. It provides a basis from which recommendations from the DOIT Committee to the federal government can be made. It also includes observations from two public roundtables, one on commercialization and another on regulatory and institutional barriers impeding technology development and cleanup

  14. Organization of left–right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling

    Science.gov (United States)

    Shevtsova, Natalia A; Talpalar, Adolfo E; Markin, Sergey N; Harris-Warrick, Ronald M; Kiehn, Ole; Rybak, Ilya A

    2015-01-01

    Different locomotor gaits in mammals, such as walking or galloping, are produced by coordinated activity in neuronal circuits in the spinal cord. Coordination of neuronal activity between left and right sides of the cord is provided by commissural interneurons (CINs), whose axons cross the midline. In this study, we construct and analyse two computational models of spinal locomotor circuits consisting of left and right rhythm generators interacting bilaterally via several neuronal pathways mediated by different CINs. The CIN populations incorporated in the models include the genetically identified inhibitory (V0D) and excitatory (V0V) subtypes of V0 CINs and excitatory V3 CINs. The model also includes the ipsilaterally projecting excitatory V2a interneurons mediating excitatory drive to the V0V CINs. The proposed network architectures and CIN connectivity allow the models to closely reproduce and suggest mechanistic explanations for several experimental observations. These phenomena include: different speed-dependent contributions of V0D and V0V CINs and V2a interneurons to left–right alternation of neural activity, switching gaits between the left–right alternating walking-like activity and the left–right synchronous hopping-like pattern in mutants lacking specific neuron classes, and speed-dependent asymmetric changes of flexor and extensor phase durations. The models provide insights into the architecture of spinal network and the organization of parallel inhibitory and excitatory CIN pathways and suggest explanations for how these pathways maintain alternating and synchronous gaits at different locomotor speeds. The models propose testable predictions about the neural organization and operation of mammalian locomotor circuits. Key points Coordination of neuronal activity between left and right sides of the mammalian spinal cord is provided by several sets of commissural interneurons (CINs) whose axons cross the midline. Genetically identified inhibitory V

  15. Effects of experimental muscle pain on muscle activity and co-ordination during static and dynamic motor function.

    Science.gov (United States)

    Graven-Nielsen, T; Svensson, P; Arendt-Nielsen, L

    1997-04-01

    The relation between muscle pain, muscle activity, and muscle co-ordination is still controversial. The present human study investigates the influence of experimental muscle pain on resting, static, and dynamic muscle activity. In the resting and static experiments, the electromyography (EMG) activity and the contraction force of m. tibialis anterior were assessed before and after injection of 0.5 ml hypertonic saline (5%) into the same muscle. In the dynamic experiment, injections of 0.5 ml hypertonic saline (5%) were performed into either m. tibialis anterior (TA) or m. gastrocnemius (GA) and the muscle activity and co-ordination were investigated during gait on a treadmill by EMG recordings from m. TA and m. GA. At rest no evidence of EMG hyperactivity was found during muscle pain. The maximal voluntary contraction (MVC) during muscle pain was significantly lower than the control condition (P Fibromyalgia and Myofascial Pain. Elsevier, Amsterdam, 1993, pp. 311-327.) which predicts increased activity of antagonistic muscle and decreased activity of agonistic muscle during experimental and clinical muscle pain.

  16. Reproducibility of liver position using active breathing coordinator for liver cancer radiotherapy

    International Nuclear Information System (INIS)

    Eccles, Cynthia; Brock, Kristy K.; Bissonnette, Jean-Pierre; Hawkins, Maria; Dawson, Laura A.

    2006-01-01

    Purpose: To measure the intrabreath-hold liver motion and the intrafraction and interfraction reproducibility of liver position relative to vertebral bodies using an active breathing coordinator (ABC) in patients with unresectable liver cancer treated with hypofractionated stereotactic body radiation therapy (SBRT). Methods: Tolerability of ABC and organ motion during ABC was assessed using kV fluoroscopy in 34 patients. For patients treated with ABC, repeat breath-hold CT scans in the ABC breath-hold position were acquired at simulation to estimate the volumetric intrafraction reproducibility of the liver relative to the vertebral bodies. In addition, preceding each radiation therapy fraction, with the liver immobilized using ABC, repeat anteroposterior (AP) megavoltage verification images were obtained. Off-line alignments were completed to determine intrafraction reproducibility (from repeat images obtained before one treatment) and interfraction reproducibility (from comparisons of the final image for each fraction with the AP) of diaphragm position relative to vertebral bodies. For each image set, the vertebral bodies were aligned, and the resultant craniocaudal (CC) offset in diaphragm position was measured. Liver position during ABC was also evaluated from kV fluoroscopy acquired at the time of simulation, kV fluoroscopy at the time of treatment, and from MV beam's-eye view movie loops acquired during treatment. Results: Twenty-one of 34 patients were screened to be suitable for ABC. The average free breathing range of these patients was 13 mm (range, 5-1 mm). Fluoroscopy revealed that the average maximal diaphragm motion during ABC breath-hold was 1.4 mm (range, 0-3.4 mm). The MV treatment movie loops confirmed diaphragm stability during treatment. For a measure of intrafraction reproducibility, an analysis of 36 repeat ABC computed tomography (CT) scans in 14 patients was conducted. The average mean difference in the liver surface position was -0.9 mm, -0

  17. 76 FR 30229 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-05-24

    .... --Consideration of IACS unified interpretations. --Harmonization of the requirements for the location of entrances.... --Development of unified interpretations for chapter 7 of the 2000 HSC Code. --Development of amendments to the FSS Code for communication equipment for fire-fighting teams. --Development of guidelines for use of...

  18. 77 FR 70526 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-11-26

    ... from machinery spaces --Development of requirements for ships carrying hydrogen and compressed natural gas vehicles --Consideration of IACS unified interpretations --Harmonization of the requirements for the location of entrances, air inlets and openings in the superstructures of tankers --Development of...

  19. 75 FR 10546 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-03-08

    ... prevent explosions on oil and chemical tankers transporting low flash point cargoes --Clarification of... on evacuation analysis for new and existing passenger ships --Consideration of IACS unified interpretations --Fixed hydrocarbon gas detection systems on double-hull tankers --Harmonization of the...

  20. 77 FR 57637 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-09-18

    ... organizations --Relations with non-governmental organizations --Day of the Seafarer --Report on World Maritime... Organization --Voluntary IMO Member State Audit Scheme --Consideration of the report of the Marine Environment... relating to the 1977 Torremolinos Convention on the Safety of Fishing Vessels --IMO International Maritime...

  1. 76 FR 44977 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-07-27

    ... traffic. --Formalities connected with the arrival, stay and departure of persons. --Certificates and.... --Installation of equipment for detection of radioactive contaminated objects in port. --Amendments to the...

  2. 75 FR 39089 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-07-07

    ... strategy implementation plan --Guidelines on the layout and ergonomic design of safety centers on passenger... Session of the International Maritime Organization (IMO) Subcommittee on Safety of Navigation to be held... than 500 meters around artificial islands, installations and structures in the EEZ --Amendments to the...

  3. 78 FR 8682 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-02-06

    ... guidelines in relation to the Maritime Labour Convention, 2006; Development of guidelines on port State... of the room. To facilitate the building security process, and to request reasonable accommodation... accommodated. Please note that due to security considerations, two valid, government issued photo...

  4. 75 FR 82129 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-12-29

    ... hours and PSC guidelines in relation to the Maritime Labour Convention, 2006; -- Development of... security process, and to request reasonable accommodation, those who plan to attend should contact one of.... Requests made after February 8, 2011 might not be able to be accommodated. Please note that due to security...

  5. 75 FR 27856 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-05-18

    ... hours and PSC guidelines in relation to the Maritime Labour Convention, 2006; --Development of... building security process and to request reasonable accommodation, those who plan to attend should contact... that due to security considerations, two valid, government issued photo identifications must be...

  6. 78 FR 2479 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-01-11

    ... (PSC) Guidelines on seafarers' hours of rest and PSC guidelines in relation to the Maritime Labour... building security process, and to request reasonable accommodation, those who plan to attend should contact.... Requests made after this date might not be able to be accommodated. Please note that due to security...

  7. 77 FR 12353 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-02-29

    ...); Provision of financial security in cases of abandonment, personal injury to, or death of seafarers related to entry into force of the International Labour Organization Maritime Labour Convention, 2006; Fair... to the seating capacity of the room. To facilitate the building security process, and to request...

  8. 77 FR 5614 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-02-03

    ...) Guidelines on seafarers' hours of rest and PSC guidelines in relation to the Maritime Labour Convention, 2006... of the room. To facilitate the building security process, and to request reasonable accommodation... be accommodated. Please note that due to security considerations, two valid, government issued photo...

  9. 78 FR 17467 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-03-21

    ... and Noxious Substances by Sea. --Provision of financial security in cases of abandonment, personal injury to, or death of seafarers related to entry into force of the International Labour Organization Maritime Labour Convention, 2006. --Fair treatment of seafarers in the event of a maritime accident...

  10. 76 FR 82027 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2011-12-29

    ... Headquarters Building, 2100 2nd Street SW., Washington, DC 20593-7126. The primary purpose of the meeting is to... primary purpose of the meeting is to prepare for the sixty- third session of the International Maritime... considered include: --Adoption of the Agenda; --Harmful aquatic organisms in ballast water; --Recycling of...

  11. 75 FR 8176 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-02-23

    ..., SW., Washington, DC 20593-0001. The primary purpose of the meeting is to prepare for the sixtieth... matters to be considered include: --Harmful aquatic organisms in ballast water --Recycling of ships...

  12. 78 FR 14400 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-03-05

    ..., 2100 Second Street SW., Washington, DC, 20593. The primary purpose of the meeting is to prepare for the... ballast water; --Recycling of ships; --Air pollution and energy efficiency; --Reduction of GHG emissions...

  13. 77 FR 52105 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-08-28

    ... Building, 2100 Second Street SW., Washington, DC, 20593. The primary purpose of the meeting is to prepare... organisms in ballast water; --Recycling of ships; --Air pollution and energy efficiency; --Reduction of GHG...

  14. 77 FR 54648 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2012-09-05

    ... Building, 2100 Second Street SW., Washington, DC 20593. The primary purpose of the meeting is to prepare... organisms in ballast water; --Recycling of ships; --Air pollution and energy efficiency; --Reduction of GHG...

  15. 78 FR 2479 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2013-01-11

    ... thermal performance of immersion suits; --Development of amendments to the LSA Code for free-fall....2 and 29.4.2, clarifying the requirements for steering gear trials; --Work programme --Any other...

  16. 75 FR 54415 - Shipping Coordinating Committee; Notice of Committee Meeting

    Science.gov (United States)

    2010-09-07

    ... Code for ships operating in polar waters; --Thermal performance of immersion suits; --Protection... equipment; --Measures to promote integrated bilge water treatment systems; --Guidelines for a shipboard oil waste pollution prevention plan; --Manually operated alternatives in the event of prevention pollution...

  17. 78 FR 44519 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2013-07-24

    ... and water quality, soil conservation, biological diversity, carbon storage, forest products, forestry-related jobs, production of renewable energy, wildlife, wildlife corridors and wildlife habitat, and..., individuals with demonstrated ability to represent minorities, women, persons with disabilities, and senior...

  18. 76 FR 79151 - Forest Resource Coordinating Committee

    Science.gov (United States)

    2011-12-21

    ... with State agencies and the private sector, to effectively address the national priorities for non-industrial private forest land. DATES: The meeting will be held on January 20, 2012. ADDRESSES: The meeting.... Comments may also be sent via email to [email protected]us , or via facsimile to (202) 205-1271. All...

  19. 78 FR 7757 - Council Coordination Committee Meeting

    Science.gov (United States)

    2013-02-04

    ... issues of relevance to the Councils, including FY 2013 budget allocations and budget planning for FY 2014... will be held at the Sheraton Silver Spring Hotel, 8777 Georgia Avenue, Silver Spring, MD 20001... reports (continued) 11:15-12:15--Management and Budget Update FY2012: Status, Council funding FY2013...

  20. 75 FR 81232 - Council Coordination Committee Meeting

    Science.gov (United States)

    2010-12-27

    ... issues of relevance to the Councils, including FY 2011 budget allocations and budget planning, Annual... be held at the Phoenix Park Hotel, 520 North Capitol Street, NW., Washington, DC 20001, telephone 1...:30-2:15 Performance Measures. 2:15-3:15 Budget Issues FY11: Status, Allocation, Council Grants. FY12...

  1. PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

    OpenAIRE

    Shrestha, Yashaswi; Schafer, Eric J.; Boehm, Jesse S.; Thomas, Sapana R.; He, Frank; Du, Jinyan; Wang, Shumei; Barretina, Jordi; Weir, Barbara A.; Zhao, Jean J.; Polyak, Kornelia; Golub, Todd R.; Beroukhim, Rameen; Hahn, William C.

    2011-01-01

    Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of the RAS-RAF-MEK-ERK Mitogen-Activated Protein Kinase (MAPK) pathway is commonly observed in human breast cancers, suggesting that other genetic alterations lead to activation of this signaling pathway. To identify breast cancer oncogenes that activate the MAPK pathway, we screened a library of human kinases for their ability to induce ...

  2. Seismic safety programme at NPP Paks. Propositions for coordinated international activity in seismic safety of the WWER-440 V-213

    International Nuclear Information System (INIS)

    Katona, T.

    1995-01-01

    This paper presents the Paks NPP seismic safety program, highlighting the specifics of the WWER-440/213 type in operation, and the results of work obtained so far. It covers the following scope: establishment of the seismic safety program (original seismic design, current requirements, principles and structure of the seismic safety program); implementation of the seismic safety program (assessing the seismic hazard of the site, development of the new concept of seismic safety for the NPP, assessing the seismic resistance of the building and the technology); realization of the seismic safety of higher level (technical solutions, drawings, realization); ideas and propositions for coordinated international activity

  3. Coordinated control of active and reactive power of distribution network with distributed PV cluster via model predictive control

    Science.gov (United States)

    Ji, Yu; Sheng, Wanxing; Jin, Wei; Wu, Ming; Liu, Haitao; Chen, Feng

    2018-02-01

    A coordinated optimal control method of active and reactive power of distribution network with distributed PV cluster based on model predictive control is proposed in this paper. The method divides the control process into long-time scale optimal control and short-time scale optimal control with multi-step optimization. The models are transformed into a second-order cone programming problem due to the non-convex and nonlinear of the optimal models which are hard to be solved. An improved IEEE 33-bus distribution network system is used to analyse the feasibility and the effectiveness of the proposed control method

  4. A Group Motor Skills Program for Children with Coordination Difficulties: Effect on Fundamental Movement Skills and Physical Activity Participation.

    Science.gov (United States)

    Kane, Kyra J; Staples, Kerri L

    2016-01-01

    Children with coordination difficulties are at risk of low levels of physical activity (PA) participation. This intervention examined the effects of a multidisciplinary program that emphasized parent participation on motor skill performance and PA. Ten boys (5-7 years) completed a group program consisting of conditioning exercises and activities designed to address child-selected goals. Motor proficiency and PA participation were assessed before and after the program using the Test of Gross Motor Development (TGMD-2) and triaxial accelerometers, respectively. Rating scales captured child and parent perceptions of performance for each child's goals. TGMD-2 subtest raw scores, age equivalent and percentile scores improved, along with parent ratings of their child's performance. Six children reported skill improvements. On average, moderate to vigorous PA improved by 10 min per day although these gains were not significant. Time spent in sedentary activities was unchanged. None of the children met the Canadian PA and sedentary behaviour guidelines. The results support effectiveness of a group program to improve gross motor performance and levels of PA in children with coordination difficulties. Gains in both of these domains also have the potential to impact quality of life and reduce health risks associated with inactivity.

  5. Relationship between motor skills, participation in leisure activities and quality of life of children with Developmental Coordination Disorder: temporal aspects.

    Science.gov (United States)

    Raz-Silbiger, S; Lifshitz, N; Katz, N; Steinhart, S; Cermak, S A; Weintraub, N

    2015-03-01

    The study examined the relationship between motor skills, participation in leisure activities and quality of life (QOL), within a temporal context (school year vs. summer vacation and school days vs. weekends). Parents of 22 children with Developmental Coordination Disorder (DCD) and of 55 typically developing children, aged 6-11, filled out two questionnaires relating to their children's participation in leisure activities (vigorous, moderate and sedentary) and QOL. The Movement Assessment Battery for Children-2 (MABC-2) was administered to their children. Results showed that among the children with DCD, balance scores positively correlated with participation in sedentary activities, and in both groups both balance and aiming and catching were related to the physical and school aspects of QOL. Furthermore, participation in vigorous activities in the summer was positively correlated with social and school QOL. In contrast, among typically developing children, participation in vigorous activities during the school year was negatively correlated with school QOL. Finally, in both groups, participation in sedentary activities during school days was negatively correlated with school QOL. These results suggest that the parents' perceptions of their children's QOL may be related to the level of activeness of the leisure activities but also to temporal aspects. Therefore, it is important that therapists and educators consider the temporal aspects, when consulting with parents and their children regarding participation in leisure activities. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. TU-G-213-01: IEC and US Committee Activities and Organizational Structure

    Energy Technology Data Exchange (ETDEWEB)

    Ibbott, G. [UT MD Anderson Cancer Center (United States)

    2015-06-15

    The International Electrotechnical Commission (IEC) writes standards that manufacturers of electrical equipment must comply with. Medical electrical equipment, such as medical imaging, radiation therapy, and radiation dosimetry devices, fall under Technical Committee 62. Of particular interest to medical physicists are the standards developed within Subcommittees (SC) 62B, which addresses diagnostic radiological imaging equipment, and 62C, which addresses equipment for radiation therapy, nuclear medicine and dosimetry. For example, a Working Group of SC 62B is responsible for safety and quality assurance standards for CT scanners and a Working Group of SC 62C is responsible for standards that set requirements for dosimetric safety and accuracy of linacs and proton accelerators. IEC standards thus have an impact on every aspect of a medical physicist’s job, including equipment testing, shielding design, room layout, and workflow. Consequently, it is imperative that US medical physicists know about existing standards, as well as have input on those under development or undergoing revision. The structure of the IEC and current standards development work will be described in detail. The presentation will explain how US medical physicists can learn about IEC standards and contribute to their development. Learning Objectives: Learn about the structure of the IEC and the influence that IEC standards have on the design of equipment for radiology and radiation therapy. Learn about the mechanisms by which the US participates in the development and revision of standards. Understand the specific requirements of several standards having direct relevance to diagnostic and radiation therapy physicists.

  7. Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study

    DEFF Research Database (Denmark)

    Kjaerulff, O; Kiehn, O

    1996-01-01

    The isolated spinal cord of the newborn rat contains networks that are able to create a patterned motor output resembling normal locomotor movements. In this study, we sought to localize the regions of primary importance for rhythm and pattern generation using specific mechanical lesions. We used...... ventral root recordings to monitor neuronal activity and tested the ability of various isolated parts of the caudal thoraciclumbar cord to generate rhythmic bursting in a combination of 5-HT and NMDA. In addition, pathways mediating left/right and rostrocaudal burst alternation were localized. We found......, these pathways were distributed along the lumbar enlargement. Both lateral and ventral funiculi were sufficient to coordinate activity in the rostral and caudal regions. We conclude that the networks organizing locomotor-related activity in the spinal cord of the newborn rat are distributed....

  8. Association between physical activity and motor skills and coordination in Portuguese children. DOI: 10.5007/1980-0037.2011v13n1p15

    Directory of Open Access Journals (Sweden)

    Beatriz Pereira

    2011-01-01

    Full Text Available Nowadays, there is growing evidence in literature that Health benefits from regular physical activity (PA. The variance in PA among children is caused by a number of factors including their motor abilities and coordination. The aim of the study was to analyse the relation between usual PA and gross motor abilities and motor coordination in children aged 6 to 7 years. The sample comprised 21 children, aged in average 6,38±0,50 years. Physical activity was accessed by accelerometry, gross motor abilities by using the Test of Gross Motor Development (TGMD-2 and motor coordination by using the Körperkoordination Test für Kinder (KTK. Subjects met the international recommendations for daily PA; in motor coordination 47,6% of children met normal coordination, nobody reach good or very good coordination, the majority (52,4% revelled disturbances or insufficiencies of coordination; in locomotion TGMD-2 76,2% of the children met percentile 50 or superior (P50, in object control TGMD-2 28,6% of the children reach P50 or superior, in total TGMD-2 38,1% of the children met P50 or superior. PA was positively correlated with TGMD-2 object control. Low performance attributed to the children in TGMD-2 and KTK tests could be an indicative of insufficient in the development of coordination and gross motor abilities; therefore we believe that this kind of intervention should be targeted at school children mainly in Physical Education classes.

  9. Fluorescent sensing of nitroaromatics by two coordination polymers having potential active sites

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Lu [College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000 (China); Institute of Functional Materials, Sichuan University of Science & Engineering, Zigong 643000 (China); Wang, Jun, E-mail: scwangjun2011@126.com [College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000 (China); Institute of Functional Materials, Sichuan University of Science & Engineering, Zigong 643000 (China); Wu, Wei-Ping [College of Chemistry and Environmental Engineering, Sichuan University of Science & Engineering, Zigong 643000 (China); Institute of Functional Materials, Sichuan University of Science & Engineering, Zigong 643000 (China); Ma, Aiqing, E-mail: maqandght@126.com [School of Pharmacy, Guangdong Medical University, Dongguan 523808 (China); Liu, Jian-Qiang [School of Pharmacy, Guangdong Medical University, Dongguan 523808 (China); Yadav, Reena [Department of Chemistry, Faculty of Science, University of Lucknow, Lucknow 226 007 (India); Kumar, Abhinav, E-mail: abhinavmarshal@gmail.com [Department of Chemistry, Faculty of Science, University of Lucknow, Lucknow 226 007 (India)

    2017-06-15

    Two new d{sup 10} based coordination polymers having formula [Cd(HL1)(L2)] (1) and [Zn(HL1)(L2)] (2) (H{sub 3}L1=5-(4-carboxyphenoxy)isophthalic acid and L2=3-(4-methyl-6-(pyridine-3-yl)pyridine-2-yl)pyridine) have been synthesized and characterized using IR, thermogravimetric analyses (TGA), photoluminescence and single-crystal X-ray diffraction techniques. The single-crystal X-ray investigation reveals that both of 1 and 2 show 2D layer architectures with square lattice topology. The photoluminescence investigation indicates that both 1 and 2 could be a prospective candidate for developing luminescence sensors for the highly sensing of nitroaromatic analytes. Furthermore, the luminescent property of 1 and 2 in different solvents analytes as well as nitrobenzene derivative have been investigated and the observed quenching in fluorescence have been corroborated by theoretical calculations. - Graphical abstract: Two new d{sup 10}-based luminescent MOFs synthesized and their sensing properties towards different nitroaromatics investigated.

  10. Summary of the progress of reactor physics in Japan reviewing the activities related to NEA Committee on Reactor Physics

    International Nuclear Information System (INIS)

    Hirota, Jitsuya

    1984-09-01

    The progress of fast and thermal reactor physics, fusion neutronics and shielding researches in these twenty years can be clearly recognized in the reviews of reactor physics activities in Japan which had been perpared by the Special Committee on Reactor Physics: the joint committee under Atomic Energy Society of Japan and JAERI. Many topics of those discussed at the NEACRP meetings concerned fast reactor physics. Information exchange on the topics such as adjustment of group cross sections by integral data, central worth discrepancy, sodium void effect and heterogeneous core stimulated the researches in Japan. And achievements in Japan including those in the JAERI Fast Critical Facility FCA were reported and contributed largely to the international co-operation. In addition, the contribution from Japan was also made concerning a study of fusion blanket. Among various specialists' meetings recommended by NEACRP, those on nuclear data and benchmarks for reactor shielding were often held since 1973 and helpful to the progress of shielding researches in Japan. The Third Specialists' Meeting on Reactor Noise (SMORN-III) was held in Tokyo in 1981, indicating the recent progress in safety-related applications of reactor noise analysis. The NEACRP benchmark tests were quite useful to the progress of reactor physics in Japan, which included the benchmark calculations of BWR lattice cell, key parameters and burn-up characteristics of a large LMFBR, FBR and PWR shielding, and so on. It may be noted that the benchmark test on reactor noise analysis methods was successfully conducted by Japan in connection with SMORN-III. In addition, the co-operation was positively made to the compilation of light water lattice data, and the preparation of reviews on actinide production and burn-up, and blanket physics. (J.P.N.)

  11. Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation.

    Science.gov (United States)

    Bouchet, Jérôme; Del Río-Iñiguez, Iratxe; Lasserre, Rémi; Agüera-Gonzalez, Sonia; Cuche, Céline; Danckaert, Anne; McCaffrey, Mary W; Di Bartolo, Vincenzo; Alcover, Andrés

    2016-06-01

    The immunological synapse generation and function is the result of a T-cell polarization process that depends on the orchestrated action of the actin and microtubule cytoskeleton and of intracellular vesicle traffic. However, how these events are coordinated is ill defined. Since Rab and Rho families of GTPases control intracellular vesicle traffic and cytoskeleton reorganization, respectively, we investigated their possible interplay. We show here that a significant fraction of Rac1 is associated with Rab11-positive recycling endosomes. Moreover, the Rab11 effector FIP3 controls Rac1 intracellular localization and Rac1 targeting to the immunological synapse. FIP3 regulates, in a Rac1-dependent manner, key morphological events, like T-cell spreading and synapse symmetry. Finally, Rab11-/FIP3-mediated regulation is necessary for T-cell activation leading to cytokine production. Therefore, Rac1 endosomal traffic is key to regulate T-cell activation. © 2016 The Authors.

  12. Baking together-the coordination of actions in activities involving people with dementia.

    Science.gov (United States)

    Majlesi, Ali Reza; Ekström, Anna

    2016-08-01

    This study explores interaction and collaboration between people with dementia and their spouses in relation to the performance of household chores with the focus on instruction as an interactional context to engage the person with dementia in collaboration to accomplish joint activities. Dementia is generally associated with pathological changes in people's cognitive functions such as diminishing memory functions, communicative abilities and also diminishing abilities to take initiative as well as to plan and execute tasks. Using video recordings of everyday naturally occurring activities, we analyze the sequential organization of actions (see Schegloff, 2007) oriented toward the accomplishment of a joint multi-task activity of baking. The analysis shows the specific ways of collaboration through instructional activities in which the person with dementia exhibits his competence and skills in accomplishing the given tasks through negotiating the instructions with his partner and carrying out instructed actions. Although the driving force of the collaboration seems to be a series of directive sequences only initiated by the partner throughout the baking activity, our analyses highlight how the person with dementia can actively use the material environment-including collaborating partners-to compensate for challenges and difficulties encountered in achieving everyday tasks. The sequential organization of instructions and instructed actions are in this sense argued to provide an interactional environment wherein the person with dementia can make contributions to the joint activity in an efficient way. While a collaborator has been described as necessary for a person with dementia to be able to partake in activities, this study shows that people with dementia are not only guided by their collaborators in joint activities but they can also actively use their collaborators in intricate compensatory ways. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Analysis of activity and motor coordination in rats undergoing stereotactic surgery and implantation of a cannula into the dorsal hippocampus.

    Science.gov (United States)

    Hernández-López, F; Rodríguez-Landa, J F; Puga-Olguín, A; Germán-Ponciano, L J; Rivadeneyra-Domínguez, E; Bernal-Morales, B

    Stereotactic surgery is used to place electrodes or cannulas in the brain in order to study the function of several brain structures in preclinical research. The hippocampus has been extensively studied with this methodology due to its involvement in a wide range of neurological, cognitive, emotional, and affective disorders. However, the effects of stereotactic surgery on coordination and motor activity should be evaluated in order to determine whether this surgical procedure causes any neurological alterations that may bias the results of studies incorporating this technique. We evaluated the effects of stereotactic surgery and implantation of a cannula into the hippocampus of female Wistar rats on the motor activity, forced swim, and rotarod tests. The stage of the oestrous cycle was included in the statistical analysis. Stereotactic surgery had no impact on any of the motor activity variables assessed in the open field (squares crossed, time spent in grooming, and rearing), forced swim (turning behaviour, lateral swimming, latency to first immobility, and time spent immobile), and rotarod (latency to fall) tests, compared with intact rats. Regardless of surgical manipulation, rats in the metestrus and diestrus stages crossed a greater number of squares and displayed longer immobility times than those in the proestrus and estrus stages. Stereotactic surgery for cannula placement in the dorsal hippocampus does not affect coordination and motor activity in rats. We can therefore conclude that this procedure has no neurological complications that may interfere in the interpretation of results of studies applying this technique. Copyright © 2016 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

  14. Review of fast reactor activities

    International Nuclear Information System (INIS)

    1982-01-01

    A description of some highlights of the activities performed by the Commission of the European Communities in the field of fast reactors is given. They fall into two categories: coordinating and harmonizing activities and research activities. The former are essentially performed in the frame of the Fast Reactor Coordinating Committee (FRCC), the latter in the Commission's Joint Research Center and to some extent under contract in research centers of the Member States

  15. Active video gaming improves body coordination in survivors of childhood brain tumours

    DEFF Research Database (Denmark)

    Sabel, M.; Sjölund, A.; Broeren, J.

    2016-01-01

    Purpose: We investigated whether active video gaming (AVG) could bring about regular, enjoyable, physical exercise in children treated for brain tumours, what level of physical activity could be reached and if the children’s physical functioning improved. Methods: Thirteen children, aged 7–17 years...... compared to their healthy peers. Active video gaming (AVG), supported by Internet coaching, is a feasible home-based intervention in children treated for brain tumours, promoting enjoyable, regular physical exercise of moderate intensity. In this pilot study, AVG with Nintendo Wii improved Body...

  16. Coordination of manganous ion at the active site of pyruvate, phosphate dikinase: the complex of oxalate with the phosphorylated enzyme

    International Nuclear Information System (INIS)

    Kofron, J.L.; Ash, D.E.; Reed, G.H.

    1988-01-01

    Electron paramagnetic resonance spectroscopy has been used to investigate the structure of the complex of manganous ion with the phosphorylated form of pyruvate, phosphate dikinase (E/sub p/) and the inhibitor oxalate. Oxalate, an analogue of the enolate of pyruvate, is competitive with respect to pyruvate in binding to the phosphorylated form of the enzyme. Superhyperfine coupling between the unpaired electrons of Mn(I) and ligands specifically labeled with 17 O has been used to identify oxygen ligands to Mn(II) in the complex with oxalate and the phosphorylated form of the enzyme. Oxalate binds at the active site as a bidentate chelate with Mn(II). An oxygen from the 3'-N-phosphohistidyl residue of the protein is in the coordination sphere of Mn(II), and at least two water molecules are also bound to Mn(II) in the complex. Oxalate also binds directly to Mn(II) in a complex with nonphosphorylated enzyme. The structure for the E/sub p/-Mn(II)-oxalate complex implies that simultaneous coordination of a phospho group and of the attacking nucleophile to the divalent cation is likely an important factor in catalysis of this phospho-transfer reaction

  17. Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation

    DEFF Research Database (Denmark)

    Jensen, Bettina M; Beaven, Michael A; Iwaki, Shoko

    2008-01-01

    Although primarily required for the growth, differentiation, and survival of mast cells, Kit ligand (stem cell factor) is also required for optimal antigen-mediated mast cell activation. Therefore, concurrent inhibition of Kit- and FcepsilonRI-mediated signaling would be an attractive approach...... characterized Kit inhibitor imatinib mesylate (imatinib). In contrast to imatinib, however, hypothemycin also effectively inhibited FcepsilonRI-mediated degranulation and cytokine production in addition to the potentiation of these responses via Kit. The effect of hypothemycin on Kit-mediated responses could...... be explained by its inhibition of Kit kinase activity, whereas the inhibitory effects on FcepsilonRI-dependent signaling were at the level of Btk activation. Because hypothemycin also significantly reduced the mouse passive cutaneous anaphylaxis response in vivo, these data provide proof of principle...

  18. Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells

    International Nuclear Information System (INIS)

    Hirose, Yoshikazu; Itoh, Tohru; Miyajima, Atsushi

    2009-01-01

    Hedgehog (Hh) signaling plays crucial roles in development and homeostasis of various organs. In the adult liver, it regulates proliferation and/or viability of several types of cells, particularly under injured conditions, and is also implicated in stem/progenitor cell maintenance. However, the role of this signaling pathway during the normal developmental process of the liver remains elusive. Although Sonic hedgehog (Shh) is expressed in the ventral foregut endoderm from which the liver derives, the expression disappears at the onset of the liver bud formation, and its possible recurrence at the later stages has not been investigated. Here we analyzed the activation and functional relevance of Hh signaling during the mouse fetal liver development. At E11.5, Shh and an activation marker gene for Hh signaling, Gli1, were expressed in Dlk + hepatoblasts, the fetal liver progenitor cells, and the expression was rapidly decreased thereafter as the development proceeded. In the culture of Dlk + hepatoblasts isolated from the E11.5 liver, activation of Hh signaling stimulated their proliferation and this effect was cancelled by a chemical Hh signaling inhibitor, cyclopamine. In contrast, hepatocyte differentiation of Dlk + hepatoblasts in vitro as manifested by the marker gene expression and acquisition of ammonia clearance activity was significantly inhibited by forced activation of Hh signaling. Taken together, these results demonstrate the temporally restricted manner of Hh signal activation and its role in promoting the hepatoblast proliferation, and further suggest that the pathway needs to be shut off for the subsequent hepatic differentiation of hepatoblasts to proceed normally.

  19. First research coordination meeting on reference database for neutron activation analysis. Summary report

    International Nuclear Information System (INIS)

    Firestone, R.B.; Trkov, A.

    2005-10-01

    Potential problems associated with nuclear data for neutron activation analysis were identified, the scope of the work to be undertaken was defined together with its priorities, and tasks were assigned to participants. Data testing and measurements refer to gamma spectrum peak evaluations, detector efficiency calibration, neutron spectrum characteristics and reference materials analysis. (author)

  20. Advancing science and policy through a coordinated international study of physical activity and built environments

    DEFF Research Database (Denmark)

    Kerr, Jacqueline; Sallis, James F; Owen, Neville

    2013-01-01

    National and international strategies to increase physical activity emphasize environmental and policy changes that can have widespread and long-lasting impact. Evidence from multiple countries using comparable methods is required to strengthen the evidence base for such initiatives. Because some...

  1. SYNTHESIS AND ANTITUMOR ACTIVITY OF COPPER, NICKEL AND COBALT COORDINATION COMPOUNDS WITH 1-(2-HYDROXYPHENYL)ETHANONE N(4)-ALLYL-3-THIOSEMICARBAZONE

    OpenAIRE

    Vasilii GRAUR; Serghei SAVCIN; Victor TSAPKOV; Aurelian GULEA

    2015-01-01

    The paper presents the synthesis of the ligand 1-(2-hydroxyphenyl)ethanone N(4)-allyl-3-thiosemicarbazone (H2L) and six coordination compounds of copper, nickel and cobalt with this ligand. The structure of thiosemicarbazone H2L was studied using 1H and 13С NMR spectroscopy. The synthesized coordination compounds were studied using elemental analysis, gravimetric analysis of water content, molar conductivity, and magnetochemistry. For H2L the antitumor activity towards human leukemia HL-60 ce...

  2. Coordinating structural and functional synapse development: postsynaptic p21-activated kinase independently specifies glutamate receptor abundance and postsynaptic morphology.

    Science.gov (United States)

    Albin, Stephanie D; Davis, Graeme W

    2004-08-04

    Here, we show that postsynaptic p21-activated kinase (Pak) signaling diverges into two genetically separable pathways at the Drosophila neuromuscular junction. One pathway controls glutamate receptor abundance. Pak signaling within this pathway is specified by a required interaction with the adaptor protein Dreadlocks (Dock). We demonstrate that Dock is localized to the synapse via an Src homology 2-mediated protein interaction. Dock is not necessary for Pak localization but is necessary to restrict Pak signaling to control glutamate receptor abundance. A second genetically separable function of Pak kinase signaling controls muscle membrane specialization through the regulation of synaptic Discs-large. In this pathway, Dock is dispensable. We present a model in which divergent Pak signaling is able to coordinate two different features of postsynaptic maturation, receptor abundance, and muscle membrane specialization.

  3. Conformational Activation of Argonaute by Distinct yet Coordinated Actions of the Hsp70 and Hsp90 Chaperone Systems.

    Science.gov (United States)

    Tsuboyama, Kotaro; Tadakuma, Hisashi; Tomari, Yukihide

    2018-05-17

    Loading of small RNAs into Argonaute, the core protein in RNA silencing, requires the Hsp70/Hsp90 chaperone machinery. This machinery also activates many other clients, including steroid hormone receptors and kinases, but how their structures change during chaperone-dependent activation remains unclear. Here, we utilized single-molecule Förster resonance energy transfer (smFRET) to probe the conformational changes of Drosophila Ago2 mediated by the chaperone machinery. We found that empty Ago2 exists in various closed conformations. The Hsp70 system (Hsp40 and Hsp70) and the Hsp90 system (Hop, Hsp90, and p23) together render Ago2 into an open, active form. The Hsp70 system, but not the Hsp90 system alone, is sufficient for Ago2 to partially populate the open form. Instead, the Hsp90 system is required to extend the dwell time of Ago2 in the open state, which must be transiently primed by the Hsp70 system. Our data uncover distinct and coordinated actions of the chaperone machinery, where the Hsp70 system expands the structural ensembles of Ago2 and the Hsp90 system captures and stabilizes the active form. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. ACTIVE POWER LOSSES IN LONG LINES DURING COORDINATED, LIMITING AND MALFUNCTION BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Rimsky V.X.

    2008-04-01

    Full Text Available Exact formulas for calculation of limiting values of transmitted capacity and efficiency of lines of a variable voltage with active loading on the reception end are resulted. Critical resistance and losses of capacity are determined depending on length Air-lines of an electricity transmission of a class of a voltage 500 … 750 kV. Emergency operation in the loaded electricity transmission is investigated.

  5. Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation

    Science.gov (United States)

    Foe, Victoria E.; von Dassow, George

    2008-01-01

    The cytokinetic furrow arises from spatial and temporal regulation of cortical contractility. To test the role microtubules play in furrow specification, we studied myosin II activation in echinoderm zygotes by assessing serine19-phosphorylated regulatory light chain (pRLC) localization after precisely timed drug treatments. Cortical pRLC was globally depressed before cytokinesis, then elevated only at the equator. We implicated cell cycle biochemistry (not microtubules) in pRLC depression, and differential microtubule stability in localizing the subsequent myosin activation. With no microtubules, pRLC accumulation occurred globally instead of equatorially, and loss of just dynamic microtubules increased equatorial pRLC recruitment. Nocodazole treatment revealed a population of stable astral microtubules that formed during anaphase; among these, those aimed toward the equator grew longer, and their tips coincided with cortical pRLC accumulation. Shrinking the mitotic apparatus with colchicine revealed pRLC suppression near dynamic microtubule arrays. We conclude that opposite effects of stable versus dynamic microtubules focuses myosin activation to the cell equator during cytokinesis. PMID:18955555

  6. Managing nuclear knowledge: IAEA activities and international coordination. Including resource material full text CD-ROM

    International Nuclear Information System (INIS)

    2005-06-01

    The present CD-ROM summarizes some activities carried out by the Departments of Nuclear Energy and Nuclear Safety and Security in the area of nuclear knowledge management in the period 2003-2005. It comprises, as open resource, most of the relevant documents in full text, including policy level documents, reports, presentation material by Member States and meeting summaries. The collection starts with a reprint of the report to the IAEA General Conference 2004 on Nuclear Knowledge [GOV/2004/56-GC(48)/12] summarizing the developments in nuclear knowledge management since the 47th session of the General Conference in 2003 and covers Managing Nuclear Knowledge including safety issues and Information and Strengthening Education and Training for Capacity Building. It contains an excerpt on Nuclear Knowledge from the General Conference Resolution [GC(48)/RES/13] on Strengthening the Agency's Activities Related to Nuclear Science, Technology and Applications. On the CD-ROM itself, all documents can easily be accessed by clicking on their titles on the subject pages (also printed at the end of this Working Material). Part 1 of the CD-ROM covers the activities in the period 2003-2005 and part 2 presents a resource material full text CD-ROM on Managing Nuclear Knowledge issued in October 2003

  7. 75 FR 10293 - Office of Biotechnology Activities; Office of Science Policy; Office of the Director; Notice of a...

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Office of Biotechnology... meeting, please contact Ms. Laurie Lewallen, Advisory Committee Coordinator, Office of Biotechnology...: March 1, 2010. Amy P. Patterson, Director, Office of Biotechnology Activities, National Institutes of...

  8. Coordinated activation of PTA-ACS and TCA cycles strongly reduces overflow metabolism of acetate in Escherichia coli.

    Science.gov (United States)

    Peebo, Karl; Valgepea, Kaspar; Nahku, Ranno; Riis, Gethe; Oun, Mikk; Adamberg, Kaarel; Vilu, Raivo

    2014-06-01

    Elimination of acetate overflow in aerobic cultivation of Escherichia coli would improve many bioprocesses as acetate accumulation in the growth environment leads to numerous negative effects, e.g. loss of carbon, inhibition of growth, target product synthesis, etc. Despite many years of studies, the mechanism and regulation of acetate overflow are still not completely understood. Therefore, we studied the growth of E. coli K-12 BW25113 and several of its mutant strains affecting acetate-related pathways using the continuous culture method accelerostat (A-stat) at various specific glucose consumption rates with the aim of diminishing acetate overflow. Absolute quantitative exo-metabolome and proteome analyses coupled to metabolic flux analysis enabled us to demonstrate that onset of acetate overflow can be postponed and acetate excretion strongly reduced in E. coli by coordinated activation of phosphotransacetylase-acetyl-CoA synthetase (PTA-ACS) and tricarboxylic acid (TCA) cycles. Fourfold reduction of acetate excretion (2 vs. 8 % from total carbon) at fastest growth compared to wild type was achieved by deleting the genes responsible for inactivation of acetyl-CoA synthetase protein (pka) and TCA cycle regulator arcA. The Δpka ΔarcA strain did not accumulate any other detrimental by-product besides acetate and showed identical μ max and only ~5 % lower biomass yield compared to wild type. We conclude that a fine-tuned coordination between increasing the recycling capabilities of acetate in the PTA-ACS node through a higher concentration of active acetate scavenging Acs protein and downstream metabolism throughput in the TCA cycle is necessary for diminishing overflow metabolism of acetate in E. coli and achieving higher target product production in bioprocesses.

  9. Coordination of early cellular reactions during activation of bone resorption in the rat mandible periosteum: An immunohistochemical study

    Directory of Open Access Journals (Sweden)

    Bassam Hassan

    2017-10-01

    Full Text Available The activation step of bone remodeling remains poorly characterized. Activation comprises determination of the site to be remodeled, osteoclast precursor recruitment, their migration to the site of remodeling, and differentiation. These actions involve different compartments and cell types. The aim of this study was to investigate events and cell types involved during activation. We used a bone remodeling model in rats where extractions of the upper jaw molars initiate remodeling of the antagonist lower jaw (mandible cortex along the periosteum. In this model osteoclastic resorption peaks 4 days after extractions. We previously reported that mast cell activation in the periosteum fibrous compartment is an early event of activation, associated with recruitment of circulating monocyte osteoclast precursors. By using immunohistochemistry, we observed 9 hours after induction a spatially oriented expression of InterCellular Adhesion Molecule-1 in the vessels that was inhibited by antagonists of histamine receptors 1 and 2. It was followed at 12 hours by the recruitment of ED1+ monocytes. In parallel, at 9 hours, Vascular Cellular Adhesion Molecule-1+ fibroblast-like cells scattered in the fibrous compartment of the periosteum between the vessels and the osteogenic compartment increased; these cells may be implicated in osteoclast precursor migration. Receptor Activator of NF KappaB Ligand+ cells increased at 12 hours in the osteogenic compartment and reached a peak at 18 hours. At 24 hours the numbers of osteogenic cells and subjacent osteocytes expressing semaphorin 3a, a repulsive for osteoclast precursors, decreased before returning to baseline at 48 hours. These data show that during activation the two periosteum compartments and several cell types are coordinated to recruit and guide osteoclast precursors towards the bone surface. Keywords: Biological sciences, Cell biology, Physiology, Dentistry

  10. RUN COORDINATION

    CERN Multimedia

    Christophe Delaere

    2013-01-01

    The focus of Run Coordination during LS1 is to monitor closely the advance of maintenance and upgrade activities, to smooth interactions between subsystems and to ensure that all are ready in time to resume operations in 2015 with a fully calibrated and understood detector. After electricity and cooling were restored to all equipment, at about the time of the last CMS week, recommissioning activities were resumed for all subsystems. On 7 October, DCS shifts began 24/7 to allow subsystems to remain on to facilitate operations. That culminated with the Global Run in November (GriN), which   took place as scheduled during the week of 4 November. The GriN has been the first centrally managed operation since the beginning of LS1, and involved all subdetectors but the Pixel Tracker presently in a lab upstairs. All nights were therefore dedicated to long stable runs with as many subdetectors as possible. Among the many achievements in that week, three items may be highlighted. First, the Strip...

  11. RUN COORDINATION

    CERN Multimedia

    C. Delaere

    2013-01-01

    Since the LHC ceased operations in February, a lot has been going on at Point 5, and Run Coordination continues to monitor closely the advance of maintenance and upgrade activities. In the last months, the Pixel detector was extracted and is now stored in the pixel lab in SX5; the beam pipe has been removed and ME1/1 removal has started. We regained access to the vactank and some work on the RBX of HB has started. Since mid-June, electricity and cooling are back in S1 and S2, allowing us to turn equipment back on, at least during the day. 24/7 shifts are not foreseen in the next weeks, and safety tours are mandatory to keep equipment on overnight, but re-commissioning activities are slowly being resumed. Given the (slight) delays accumulated in LS1, it was decided to merge the two global runs initially foreseen into a single exercise during the week of 4 November 2013. The aim of the global run is to check that we can run (parts of) CMS after several months switched off, with the new VME PCs installed, th...

  12. Coordinated Respiratory Motor Activity in Nerves Innervating the Upper Airway Muscles in Rats.

    Directory of Open Access Journals (Sweden)

    Satoshi Tachikawa

    Full Text Available Maintaining the patency of the upper airway during breathing is of vital importance. The activity of various muscles is related to the patency of the upper airway. In the present study, we examined the respiratory motor activity in the efferent nerves innervating the upper airway muscles to determine the movements of the upper airway during respiration under normocapnic conditions (pH = 7.4 and in hypercapnic acidosis (pH = 7.2. Experiments were performed on arterially perfused decerebrate rats aged between postnatal days 21-35. We recorded the efferent nerve activity in a branch of the cervical spinal nerve innervating the infrahyoid muscles (CN, the hypoglossal nerve (HGN, the external branch of the superior laryngeal nerve (SLN, and the recurrent laryngeal nerve (RLN with the phrenic nerve (PN. Inspiratory nerve discharges were observed in all these nerves under normocapnic conditions. The onset of inspiratory discharges in the CN and HGN was slightly prior to those in the SLN and RLN. When the CO2 concentration in the perfusate was increased from 5% to 8% to prepare for hypercapnic acidosis, the peak amplitudes of the inspiratory discharges in all the recorded nerves were increased. Moreover, hypercapnic acidosis induced pre-inspiratory discharges in the CN, HGN, SLN, and RLN. The onset of pre-inspiratory discharges in the CN, HGN, and SLN was prior to that of discharges in the RLN. These results suggest that the securing of the airway that occurs a certain time before dilation of the glottis may facilitate ventilation and improve hypercapnic acidosis.

  13. Coordination of Project and Current Activities on the Basis of the Strategy Alignment Metamodel in the Oil and Gas Company

    Directory of Open Access Journals (Sweden)

    R. Yu. Dashkov

    2017-01-01

    Full Text Available Purpose: the purpose of this article is to describe the Strategy Alignment Metamodel of the project and current activities, which allows us to connect the Goals and Strategies for Phases of the project with the Goals and Strategies of the company at all levels of the organization through targeted measurement and application of Interpretive Models. Building Networks of Goals and Strategies, and adopting organizational solutions, you coordinate the interaction of the Project office and departments of the company. This methodology is based on a Logical Rationale of the Contexts and Assumptions for establishing Goals and Strategies both for the project and for the company, and on preparation of Contexts and Assumptions, Goals and Strategies Alignment Matrices, which provides a flexible adaptation to the internal and external environment in the process of selecting the most successful Strategies to achieve the Goals. Methods: this article is based on the concept of Goals-Questions-Metrics+ Strategies, which is adapted as another concept of strategic monitoring and control system of projects: Goals-Phases-Metrics+Strategies. These concepts have formed the basis of the Strategy Alignment Metamodel, where a technology of Phases Earned Value Management is used as a measurement system for the project activity, and Balanced scorecard is applied for current operations. Results: strategy Alignment Metamodel of the project and current activities of the company is proposed hereby. It uses modern strategic monitoring and control systems for projects: Goals-Phases-Metrics+Strategies, and for the company: Goals-Questions-Metrics+ Strategies. The interaction between these systems is based on Contexts and Assumptions, Goals and Strategies Alignment Matrices. The existence of such matrices greatly simplifies management decisions and prevents the risk of delays in the execution of project Phases based on rational participation and coordination of the company

  14. Neutron activation analysis of pollutants in human hair using research reactors. Part of a coordinated programme

    International Nuclear Information System (INIS)

    Al-Shahristani, H.I.

    1978-02-01

    Hair is a suitable indicator of man's exposure to trace element environmental pollutants. Bearing this in mind, two hundred and fifty human head hair samples were randomly collected from various regions of Iraq representing the general population. These elements were analyzed by thermal neutron activation analysis and the following elements were instrumentally determined: Cr, Fe, Co, Ni, Zn, As, Se, Br, Ag, Cd, Sb, La, Au, Hg, Th and U. The arithmetic mean, geometric mean, standard deviation and range of concentration of these elements and the frequency distributions within the population are given and compared with concentrations from other regions of the world. In general the concentrations determined for this population are similar to those reported for other areas except for Br and Fe. The possible causes of these anomalies are discussed. For certain population sub-groups, high levels of Au, Ag, Cr, Se and Hg have been measured and the reasons for these deviations are discussed

  15. A self-centering active probing technique for kinematic parameter identification and verification of articulated arm coordinate measuring machines

    International Nuclear Information System (INIS)

    Santolaria, J; Brau, A; Velázquez, J; Aguilar, J J

    2010-01-01

    A crucial task in the procedure of identifying the parameters of a kinematic model of an articulated arm coordinate measuring machine (AACMM) or robot arm is the process of capturing data. In this paper a capturing data method is analyzed using a self-centering active probe, which drastically reduces the capture time and the required number of positions of the gauge as compared to the usual standard and manufacturer methods. The mathematical models of the self-centering active probe and AACMM are explained, as well as the mathematical model that links the AACMM global reference system to the probe reference system. We present a self-calibration method that will allow us to determine a homogeneous transformation matrix that relates the probe's reference system to the AACMM last reference system from the probing of a single sphere. In addition, a comparison between a self-centering passive probe and self-centering active probe is carried out to show the advantages of the latter in the procedures of kinematic parameter identification and verification of the AACMM

  16. Coevolving residues of (beta/alpha)(8)-barrel proteins play roles in stabilizing active site architecture and coordinating protein dynamics.

    Science.gov (United States)

    Shen, Hongbo; Xu, Feng; Hu, Hairong; Wang, Feifei; Wu, Qi; Huang, Qiang; Wang, Honghai

    2008-12-01

    Indole-3-glycerol phosphate synthase (IGPS) is a representative of (beta/alpha)(8)-barrel proteins-the most common enzyme fold in nature. To better understand how the constituent amino-acids work together to define the structure and to facilitate the function, we investigated the evolutionary and dynamical coupling of IGPS residues by combining statistical coupling analysis (SCA) and molecular dynamics (MD) simulations. The coevolving residues identified by the SCA were found to form a network which encloses the active site completely. The MD simulations showed that these coevolving residues are involved in the correlated and anti-correlated motions. The correlated residues are within van der Waals contact and appear to maintain the active site architecture; the anti-correlated residues are mainly distributed on opposite sides of the catalytic cavity and coordinate the motions likely required for the substrate entry and product release. Our findings might have broad implications for proteins with the highly conserved (betaalpha)(8)-barrel in assessing the roles of amino-acids that are moderately conserved and not directly involved in the active site of the (beta/alpha)(8)-barrel. The results of this study could also provide useful information for further exploring the specific residue motions for the catalysis and protein design based on the (beta/alpha)(8)-barrel scaffold.

  17. Co-ordinate regulation of sterol biosynthesis enzyme activity during accumulation of sterols in developing rape and tobacco seed.

    Science.gov (United States)

    Harker, Mark; Hellyer, Amanda; Clayton, John C; Duvoix, Annelyse; Lanot, Alexandra; Safford, Richard

    2003-02-01

    The activities of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, sterol methyl transferase 1 and sterol acyltransferase, key enzymes involved in phytosterol biosynthesis were shown to be co-ordinately regulated during oilseed rape ( Brassica napus L.) and tobacco ( Nicotiana tabacum L.) seed development. In both plants, enzyme activities were low during the initial stages of seed development, increasing towards mid-maturation where they remained stable for a time, before declining rapidly as the oilseeds reached maturity. During seed development, the level of total sterols increased 12-fold in tobacco and 9-fold in rape, primarily due to an increase in steryl ester production. In both seed tissues, stages of maximum enzyme activity coincided with periods of high rates of sterol production, indicating developmental regulation of the enzymes to be responsible for the increases in the sterol content observed during seed development. Consistent with previous studies the data presented suggest that sterol biosynthesis is regulated by two key steps, although there may be others. The first is the regulation of carbon flux into the isoprenoid pathway to cycloartenol. The second is the flux from cycloartenol to Delta(5)-end-product sterols. The implications of the results in terms of enhancing seed sterol levels by genetic modification are also discussed.

  18. Nonlinear Modeling and Coordinate Optimization of a Semi-Active Energy Regenerative Suspension with an Electro-Hydraulic Actuator

    Directory of Open Access Journals (Sweden)

    Farong Kou

    2018-01-01

    Full Text Available In order to coordinate the damping performance and energy regenerative performance of energy regenerative suspension, this paper proposes a structure of a vehicle semi-active energy regenerative suspension with an electro-hydraulic actuator (EHA. In light of the proposed concept, a specific energy regenerative scheme is designed and a mechanical properties test is carried out. Based on the test results, the parameter identification for the system model is conducted using a recursive least squares algorithm. On the basis of the system principle, the nonlinear model of the semi-active energy regenerative suspension with an EHA is built. Meanwhile, linear-quadratic-Gaussian control strategy of the system is designed. Then, the influence of the main parameters of the EHA on the damping performance and energy regenerative performance of the suspension is analyzed. Finally, the main parameters of the EHA are optimized via the genetic algorithm. The test results show that when a sinusoidal is input at the frequency of 2 Hz and the amplitude of 30 mm, the spring mass acceleration root meam square value of the optimized EHA semi-active energy regenerative suspension is reduced by 22.23% and the energy regenerative power RMS value is increased by 40.51%, which means that while meeting the requirements of vehicle ride comfort and driving safety, the energy regenerative performance is improved significantly.

  19. Evaluating Physical Activity Using Accelerometry in Children at Risk of Developmental Coordination Disorder in the Presence of Attention Deficit Hyperactivity Disorder

    Science.gov (United States)

    Baerg, Sally; Cairney, John; Hay, John; Rempel, Lynn; Mahlberg, Nadilein; Faught, Brent E.

    2011-01-01

    Physical activity (PA) is compromised in children and adolescents with developmental coordination disorder (DCD). Approximately half of all children with DCD suffer from attention-deficit hyperactive disorder (ADHD); a cohort often considered more physically active than typically developing youth. Accelerometry is an effective method of assessing…

  20. Data Management Coordinators (DMC)

    Science.gov (United States)

    The Regional Data Management Coordinators (DMCs) were identified to serve as the primary contact for each region for all Water Quality Framework activities. They will facilitate and communicate information to the necessary individuals at the region and tra

  1. Poisson Coordinates.

    Science.gov (United States)

    Li, Xian-Ying; Hu, Shi-Min

    2013-02-01

    Harmonic functions are the critical points of a Dirichlet energy functional, the linear projections of conformal maps. They play an important role in computer graphics, particularly for gradient-domain image processing and shape-preserving geometric computation. We propose Poisson coordinates, a novel transfinite interpolation scheme based on the Poisson integral formula, as a rapid way to estimate a harmonic function on a certain domain with desired boundary values. Poisson coordinates are an extension of the Mean Value coordinates (MVCs) which inherit their linear precision, smoothness, and kernel positivity. We give explicit formulas for Poisson coordinates in both continuous and 2D discrete forms. Superior to MVCs, Poisson coordinates are proved to be pseudoharmonic (i.e., they reproduce harmonic functions on n-dimensional balls). Our experimental results show that Poisson coordinates have lower Dirichlet energies than MVCs on a number of typical 2D domains (particularly convex domains). As well as presenting a formula, our approach provides useful insights for further studies on coordinates-based interpolation and fast estimation of harmonic functions.

  2. 77 FR 57567 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-09-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  3. 77 FR 50690 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-08-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  4. 77 FR 15760 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-03-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  5. 76 FR 39108 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-07-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of... the public. Name of Committee: HIT Policy Committee. General Function of the Committee: to provide...

  6. 77 FR 37407 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-06-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  7. 76 FR 22397 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  8. 77 FR 22787 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-04-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  9. 77 FR 27459 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  10. 76 FR 28783 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  11. 76 FR 79684 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-12-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  12. 77 FR 73660 - HIT Policy Committee Advisory Meetings; Notice of Meetings

    Science.gov (United States)

    2012-12-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  13. 77 FR 28881 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  14. 76 FR 46298 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  15. 77 FR 65691 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  16. 76 FR 70455 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  17. 77 FR 66617 - HIT Policy and Standards Committees; Workgroup Application Database

    Science.gov (United States)

    2012-11-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy and Standards Committees; Workgroup Application... of New ONC HIT FACA Workgroup Application Database. The Office of the National Coordinator (ONC) has.... Name of Committees: HIT Standards Committee and HIT Policy Committee. General Function of the...

  18. 77 FR 2727 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-01-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  19. 76 FR 14975 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  20. 76 FR 50734 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  1. 76 FR 55912 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... the public. Name of Committee: HIT Policy Committee. General Function of the Committee: To provide...

  2. 77 FR 41788 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-07-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  3. Neural signatures of social conformity: A coordinate-based activation likelihood estimation meta-analysis of functional brain imaging studies.

    Science.gov (United States)

    Wu, Haiyan; Luo, Yi; Feng, Chunliang

    2016-12-01

    People often align their behaviors with group opinions, known as social conformity. Many neuroscience studies have explored the neuropsychological mechanisms underlying social conformity. Here we employed a coordinate-based meta-analysis on neuroimaging studies of social conformity with the purpose to reveal the convergence of the underlying neural architecture. We identified a convergence of reported activation foci in regions associated with normative decision-making, including ventral striatum (VS), dorsal posterior medial frontal cortex (dorsal pMFC), and anterior insula (AI). Specifically, consistent deactivation of VS and activation of dorsal pMFC and AI are identified when people's responses deviate from group opinions. In addition, the deviation-related responses in dorsal pMFC predict people's conforming behavioral adjustments. These are consistent with current models that disagreement with others might evoke "error" signals, cognitive imbalance, and/or aversive feelings, which are plausibly detected in these brain regions as control signals to facilitate subsequent conforming behaviors. Finally, group opinions result in altered neural correlates of valuation, manifested as stronger responses of VS to stimuli endorsed than disliked by others. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Development of a database for prompt γ-ray neutron activation analysis. Summary report of the first research coordination meeting

    International Nuclear Information System (INIS)

    Paviotti-Corcuera, R.; Lindstrom, R.M.

    2000-02-01

    This report summarizes the presentations, recommendations and conclusions of the First Research Co-ordination Meeting on Development of a Database for Prompt γ-ray Neutron Activation Analysis. Neutron-capture Prompt γ-ray Activation Analysis (PGAA) is a non-destructive radioanalytical method, capable of rapid or in-situ simultaneous multielement analysis of many elements of the Periodic Table, from hydrogen to uranium, in the same sample. Inaccuracy and incompleteness of the data available for use in PGAA are a significant handicap in the qualitative and quantitative analysis of capture-gamma spectra. The goal of this CRP is to replace the twenty-year-old data from a single laboratory with something fundamentally new: an evaluated database which includes a combination of evaluated nuclear physics data, physical theory, and recent measurements. The resulting database will be comparable in quality with that for radioactive decay. In addition, more accurate values of neutron capture cross-sections and γ-ray intensities that result from this database will improve the accuracy of radiation shielding calculations. (author)

  5. BADERI: an online database to coordinate handsearching activities of controlled clinical trials for their potential inclusion in systematic reviews.

    Science.gov (United States)

    Pardo-Hernandez, Hector; Urrútia, Gerard; Barajas-Nava, Leticia A; Buitrago-Garcia, Diana; Garzón, Julieth Vanessa; Martínez-Zapata, María José; Bonfill, Xavier

    2017-06-13

    Systematic reviews provide the best evidence on the effect of health care interventions. They rely on comprehensive access to the available scientific literature. Electronic search strategies alone may not suffice, requiring the implementation of a handsearching approach. We have developed a database to provide an Internet-based platform from which handsearching activities can be coordinated, including a procedure to streamline the submission of these references into CENTRAL, the Cochrane Collaboration Central Register of Controlled Trials. We developed a database and a descriptive analysis. Through brainstorming and discussion among stakeholders involved in handsearching projects, we designed a database that met identified needs that had to be addressed in order to ensure the viability of handsearching activities. Three handsearching teams pilot tested the proposed database. Once the final version of the database was approved, we proceeded to train the staff involved in handsearching. The proposed database is called BADERI (Database of Iberoamerican Clinical Trials and Journals, by its initials in Spanish). BADERI was officially launched in October 2015, and it can be accessed at www.baderi.com/login.php free of cost. BADERI has an administration subsection, from which the roles of users are managed; a references subsection, where information associated to identified controlled clinical trials (CCTs) can be entered; a reports subsection, from which reports can be generated to track and analyse the results of handsearching activities; and a built-in free text search engine. BADERI allows all references to be exported in ProCite files that can be directly uploaded into CENTRAL. To date, 6284 references to CCTs have been uploaded to BADERI and sent to CENTRAL. The identified CCTs were published in a total of 420 journals related to 46 medical specialties. The year of publication ranged between 1957 and 2016. BADERI allows the efficient management of handsearching

  6. Electromyographic activity of hand muscles in a motor coordination game: effect of incentive scheme and its relation with social capital.

    Directory of Open Access Journals (Sweden)

    Roberto Censolo

    Full Text Available BACKGROUND: A vast body of social and cognitive psychology studies in humans reports evidence that external rewards, typically monetary ones, undermine intrinsic motivation. These findings challenge the standard selfish-rationality assumption at the core of economic reasoning. In the present work we aimed at investigating whether the different modulation of a given monetary reward automatically and unconsciously affects effort and performance of participants involved in a game devoid of visual and verbal interaction and without any perspective-taking activity. METHODOLOGY/PRINCIPAL FINDINGS: Twelve pairs of participants were submitted to a simple motor coordination game while recording the electromyographic activity of First Dorsal Interosseus (FDI, the muscle mainly involved in the task. EMG data show a clear effect of alternative rewards strategies on subjects' motor behavior. Moreover, participants' stock of relevant past social experiences, measured by a specifically designed questionnaire, was significantly correlated with EMG activity, showing that only low social capital subjects responded to monetary incentives consistently with a standard rationality prediction. CONCLUSIONS/SIGNIFICANCE: Our findings show that the effect of extrinsic motivations on performance may arise outside social contexts involving complex cognitive processes due to conscious perspective-taking activity. More importantly, the peculiar performance of low social capital individuals, in agreement with standard economic reasoning, adds to the knowledge of the circumstances that makes the crowding out/in of intrinsic motivation likely to occur. This may help in improving the prediction and accuracy of economic models and reconcile this puzzling effect of external incentives with economic theory.

  7. A crossover randomised and controlled trial of the impact of active video games on motor coordination and perceptions of physical ability in children at risk of Developmental Coordination Disorder.

    Science.gov (United States)

    Straker, L; Howie, E; Smith, A; Jensen, L; Piek, J; Campbell, A

    2015-08-01

    Impaired motor development can significantly affect a child's life and may result in an increased risk of a range of physical and psychological disorders. Active video game (AVG) interventions have been demonstrated to enhance motor skills in children with Developmental Coordination Disorder (DCD); however a home-based intervention has not been assessed. The primary aim of this study was to compare the changes in motor coordination between a 16 week period of AVG use, with 16 weeks of normal activities (NAG). The secondary aim was to compare the child and parent perceptions of their physical performance between the AVG and NAG conditions. Twenty-one 9-12 year olds (10 males) were confirmed to be at risk of DCD (⩽ 16th percentile Movement Assessment Battery for Children-2nd edition (MABC-2) and ⩽ 15th percentile Developmental Coordination Disorder Questionnaire (DCDQ)) and participated in this crossover randomised and controlled trial. Data was collected at study entry, after the first 16 week condition and following the final 16 week condition, including; (1) the MABC-2, (2) three-dimensional motion analysis of single leg balance and finger-nose tasks, and (3) parent perception of physical skills. Participant perception of physical skills was collected only after the first and second conditions. There was no significant difference between AVG and NAG for any of the primary variables including the MABC-2, balance centre-of-mass path distance and finger-nose path distance. There was no significant intervention effect for secondary measures of motor coordination; however the children perceived their motor skills to be significantly enhanced as a result of the AVG intervention in comparison to the period of no intervention. A 16 week home based AVG intervention did not enhance motor skills in children with DCD, although they perceived their physical skills to be significantly improved. Australia and New Zealand Clinical trials Registry (ACTRN 12611000400965

  8. Preventing Teen Pregnancy: Coordinating Community Efforts. Hearing before the Subcommittee on Human Resources and Intergovernmental Relations of the Committee on Government Reform and Oversight. House of Representatives, One Hundred Fourth Congress, Second Session.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. House Committee on Government Reform and Oversight.

    The Subcommittee on Human Resources and Intergovernmental Relations of the House of Representatives Committee on Government Reform and Oversight met to consider the causes of and solutions to teen pregnancy and the role of community organizations in prevention efforts. Opening remarks by Representative Christopher Shays were followed by statements…

  9. 75 FR 55306 - Smart Grid Advisory Committee

    Science.gov (United States)

    2010-09-10

    ... accommodate Committee business. The final agenda will be posted on the Smart Grid Web site at http://www.nist.... The Committee shall provide input to NIST on the Smart Grid Standards, Priority, and Gaps. The... research and standards activities. 5. Upon request of the Director of NIST, the Committee will prepare...

  10. Development of an Integrated Approach to Routine Automation of Neutron Activation Analysis. Results of a Coordinated Research Project

    International Nuclear Information System (INIS)

    2018-04-01

    Neutron activation analysis (NAA) is a powerful technique for determining bulk composition of major and trace elements. Automation may contribute significantly to keep NAA competitive for end-users. It provides opportunities for a larger analytical capacity and a shorter overall turnaround time if large series of samples have to be analysed. This publication documents and disseminates the expertise generated on automation in NAA during a coordinated research project (CRP). The CRP participants presented different cost-effective designs of sample changers for gamma-ray spectrometry as well as irradiation devices, and were able to construct and successfully test these systems. They also implemented, expanded and improved quality control and quality assurance as cross-cutting topical area of their automated NAA procedures. The publication serves as a reference of interest to NAA practitioners, experts, and research reactor personnel, but also to various stakeholders and users interested in basic research and/or services provided by NAA. The individual country reports are available on the CD-ROM attached to this publication.

  11. Manned space flight activities and sensory-motor coordinations; Yujin uchu katsudo tono hito no kankaku undokei

    Energy Technology Data Exchange (ETDEWEB)

    Koga, K. [Nagoya Univ., Nagoya (Japan). Research Inst. of Environmental Medicine

    1996-03-05

    With an objective to elucidate relationship between human functions related to gravity in space and the gravity, simultaneous measurement was carried out on impulsive eyeball motions and antigravity muscles. The measurement used a non-polarized electrode mounted on a prescribed position on skin. The subject is a spacecraft crew who was subjected to an experiment in space in 1992. Data obtained during the flight were analyzed, and the following findings were obtained: the eyeball motions are performed accurately in terms of space and time; potential time relative to the target appearance time showed greater variation than in control conditions on the ground; activities of trapezius muscle as an antigravity muscle were suppressed, and electric discharge from the muscle was small even if the head is moved; the eyeballs move in coordination with the head when viewing an object; microgravity environment showed a head motion with very little muscle discharge possible as in the case where the head is held unmoved; and difference in motion patterns between the antigravity muscles and non-antigravity muscles may exist as a possible cause of spacesickness in addition to the conventional sensory disagreement theory. 32 refs., 6 figs.

  12. Organizing Committee Advisory Committee 187

    Indian Academy of Sciences (India)

    Organizing Committee. V M Datar (Chairman). Bhabha Atomic Research Centre, Mumbai, India. D C Biswas (Convener). Bhabha Atomic Research Centre, Mumbai, India. K Mahata (Secretary). Bhabha Atomic Research Centre, Mumbai, India. Z Ahmed. Bhabha Atomic Research Centre, Mumbai, India. P V Bhagwat.

  13. A systematic review of instruments for assessment of capacity in activities of daily living in children with developmental co-ordination disorder

    NARCIS (Netherlands)

    van der Linde, B W; van Netten, J J; Otten, E; Postema, K; Geuze, R H; Schoemaker, M M

    Children with developmental co-ordination disorder (DCD) face evident motor difficulties in activities of daily living (ADL). Assessment of their capacity in ADL is essential for diagnosis and intervention, in order to limit the daily consequences of the disorder. The aim of this study is to

  14. A Laboratory of Extremophiles: Iceland Coordination Action for Research Activities on Life in Extreme Environments (CAREX Field Campaign

    Directory of Open Access Journals (Sweden)

    Robert Hänsch

    2013-02-01

    Full Text Available Existence of life in extreme environments has been known for a long time, and their habitants have been investigated by different scientific disciplines for decades. However, reports of multidisciplinary research are uncommon. In this paper, we report an interdisciplinary three-day field campaign conducted in the framework of the Coordination Action for Research Activities on Life in Extreme Environments (CAREX FP7EU program, with participation of experts in the fields of life and earth sciences. In situ experiments and sampling were performed in a 20 m long hot springs system of different temperature (57 °C to 100 °C and pH (2 to 4. Abiotic factors were measured to study their influence on the diversity. The CO2 and H2S concentration varied at different sampling locations in the system, but the SO2 remained the same. Four biofilms, mainly composed by four different algae and phototrophic protists, showed differences in photosynthetic activity. Varying temperature of the sampling location affects chlorophyll fluorescence, not only in the microbial mats, but plants (Juncus, indicating selective adaptation to the environmental conditions. Quantitative polymerase chain reaction (PCR, DNA microarray and denaturing gradient gel electrophoresis (DGGE-based analysis in laboratory showed the presence of a diverse microbial population. Even a short duration (30 h deployment of a micro colonizer in this hot spring system led to colonization of microorganisms based on ribosomal intergenic spacer (RISA analysis. Polyphasic analysis of this hot spring system was possible due to the involvement of multidisciplinary approaches.

  15. Effect of Mesoporous Chitosan Action and Coordination on the Catalytic Activity of Mesoporous Chitosan-Grafted Cobalt Tetrakis(p-Sulfophenyl)Porphyrin for Ethylbenzene Oxidation

    OpenAIRE

    Guan Huang; Lin Qiang Mo; Yan Xun Wei; Hong Zhou; Yong An Guo; Su Juan Wei

    2018-01-01

    To simulate the active site cavity structure function and axial coordination of cytochrome P-450 enzymes, mesoporous chitosan(mesp-CTS) was used as a scaffold for a meso-sized cavity to immobilize cobalt tetrakis(p-sulphophenyl)porphyrin chloride(Co TPPS). Immobilization was achieved via an acid–base reaction and axial coordination of the H2N-C group to the Co ion in Co TPPS, thus forming the biomimetic catalyst Co TPPS/mesp-CTS. Several approaches, including scanning electron microscop...

  16. Synthesis, structural characterization and antitumor activity of a Ca(II) coordination polymer based on 4-formyl-1,3-benzenedisulfonate-2-furoic acid hydrazide ligands

    Energy Technology Data Exchange (ETDEWEB)

    Tai, Xi-Shi, E-mail: taixs@wfu.edu.cn [Weifang University, College of Chemistry and Chemical Engineering (China); Wang, Xin [Qinghai Normal University, Department of Chemistry (China)

    2017-03-15

    A new Ca(II) coordination polymer, ([CaL(H{sub 2}O){sub 4}] · (H{sub 2}O){sub 4}){sub n} (L = 4-formyl-1,3-benzenedisulfonate-2-furoic acid hydrazide) has been prepared by one-pot synthesis method. And it was characterized by elemental analysis, IR and thermal analysis. The result of X-ray single-crystal diffraction analysis shows that the Ca(II) complex molecules form one-dimensional chain structure by the bridging oxygen atoms. The anti-tumor activity of L ligand and the Ca(II) coordination polymer has also been studied.

  17. Activity of Ethics Committees in Europe on issues related to clinical trials in paediatrics: Results of a survey

    Czech Academy of Sciences Publication Activity Database

    Altavilla, A.; Giaquinto, C.; Giocanti, D.; Manfredi, C.; Aboulker, J.-P.; Bartoloni, F.; Cattani, E.; Giudice, M. L.; Mellado Peňa, M.J.; Nagler, R.; Peterson, C.; Vajnerová, Olga; Bonifazi, F.; Ceci, A.

    2009-01-01

    Roč. 11, 1-2 (2009), s. 79-87 ISSN 1389-2827 Grant - others:EC(XE) LSHBCT-2005-005126 Institutional research plan: CEZ:AV0Z50110509 Keywords : ethic committees * clinical trials * pediatrics Subject RIV: FP - Other Medical Disciplines

  18. The Efforts of the American Geophysical Union Space Physics and Aeronomy Section Education and Public Outreach Committee to Use NASA Research in Education and Outreach

    Science.gov (United States)

    Bering, E. A., III; Dusenbery, P.; Gross, N. A.; Johnson, R.; Lopez, R. E.; Lysak, R. L.; Moldwin, M.; Morrow, C. A.; Nichols-Yehling, M.; Peticolas, L. M.; Reiff, P. H.; Scherrer, D. K.; Thieman, J.; Wawro, M.; Wood, E. L.

    2017-12-01

    The American Geophysical Union Space Physics and Aeronomy Section Education and Public Outreach Committee (AGU SPA-EPO Committee) was established in 1990 to foster the growth of a culture of outreach and community engagement within the SPA Section of the AGU. The SPA was the first AGU Section to establish an EPO Committee. The Committee has initiated several key Section EPO programs that have grown to become Union programs. NASA sponsored research is central to the mission of the SPE-EPO. Programs highlighting NASA research include the Student Paper Competition, Exploration Station, a precursor to the GIFT workshops, the Student mixer, and more. The Committee played a key role in coordinating the AGU's outreach activities relating to the International Heliophysical Year in 2007-2008. This paper will review the triumphs, the failures, and the lessons learned about recruiting colleagues to join with us from the last quarter century of effort.

  19. An active video game intervention does not improve physical activity and sedentary time of children at-risk for developmental coordination disorder: a crossover randomized trial.

    Science.gov (United States)

    Howie, E K; Campbell, A C; Straker, L M

    2016-03-01

    Children with developmental coordination disorder (DCD) are highly inactive and sedentary. The purpose of this study was to assess the impact of a home-based active video game intervention on objectively measured physical activity and sedentary behaviour in children at risk for DCD. In a crossover randomized clinical trial, 21 children (mean age 11.0, SD 1.0; n = 11 girls) in Perth, Western Australia participated in two 16-week periods: no active video games (AVGs) control period and AVGs intervention period. Two active input consoles were provided to participants along with a selection of non-violent AVGs for participants to play at home. Participants wore accelerometers at baseline and following each period to determine minutes of sedentary, light, moderate and vigorous times in addition to self-reported types of activities in a diary. Linear mixed models, adjusted for the order of periods, compared physical activity and sedentary time during the last week of each period. There were no significant differences between the intervention and control periods in time spent in sedentary (decrease of -1.0 min/day during the intervention period, 95%CI -12.1, 10.1), light (increase of 2.2 min/day, 95%CI -8.8, 13.2), moderate (decrease of 0.7 min/day, 95%CI -4.6, 3.3) or vigorous (decrease of -0.6 min/day, 95%CI -1.6, 0.4). Among children at risk for DCD, participating in this AVG intervention did not improve objectively measured physical activity and sedentary time. © 2015 John Wiley & Sons Ltd.

  20. Convergent and divergent two-dimensional coordination networks formed through substrate-activated or quenched alkynyl ligation.

    Science.gov (United States)

    Čechal, Jan; Kley, Christopher S; Kumagai, Takashi; Schramm, Frank; Ruben, Mario; Stepanow, Sebastian; Kern, Klaus

    2014-09-07

    Metal coordination assemblies of the symmetric bi-functional 4,4'-di-(1,4-buta-1,3-diynyl)-benzoic acid are investigated by scanning tunnelling microscopy on metal surfaces. The formation of long-range ordered, short-range disordered and random phases depends on the competition between the convergent and divergent coordination motifs of the individual functional groups and is crucially influenced by the substrate.

  1. Synthesis, Structural Characterization, and Antitumor Activity of a Ca(II Coordination Polymer Based on 1,6-Naphthalenedisulfonate and 4,4′-Bipyridyl

    Directory of Open Access Journals (Sweden)

    Xishi Tai

    2013-08-01

    Full Text Available A novel Ca(II coordination polymer, [CaL(4,4′-bipyridyl(H2O4]n (L = 1,6-naphthalenedisulfonate, was synthesized by reaction of calcium perchlorate with 1,6-naphthalenedisulfonic acid disodium salt and 4,4′-bipyridyl in CH3CH2OH/H2O. It was characterized by elemental analysis, IR, molar conductivity and thermogravimetric analysis. X-ray crystallography reveals that the Ca(II coordination polymer belongs to the orthorhombic system, with space group P212121. The geometry of the Ca(II ion is a distorted CaNO6 pengonal bipyramid, arising from its coordination by four water molecules, one nitrogen atom of 4,4′-bipyridyl molecule, and two oxygen atoms from two L ligands. The complex molecules form a helical chain by self-assembly. The antitumor activity of 1,6-naphthalenedisulfonic acid disodium salt and the Ca(II coordination polymer against human hepatoma smmc-7721 cell line and human lung adenocarcinoma A549 cell line reveals that the Ca(II coordination polymer inhibits cell growth of human lung adenocarcinoma A549 cell line with IC50 value of 27 μg/mL, and is more resistive to human lung adenocarcinoma A549 cell line as compared to 1,6-naphthalenedisulfonic acid disodium salt.

  2. Measuring inconsistency in research ethics committee review

    OpenAIRE

    Trace, Samantha; Kolstoe, Simon Erik

    2017-01-01

    Background The review of human participant research by Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) is a complex multi-faceted process that cannot be reduced to an algorithm. However, this does not give RECs/ IRBs permission to be inconsistent in their specific requirements to researchers or in their final opinions. In England the Health Research Authority (HRA) coordinates 67 committees, and has adopted a consistency improvement plan including a process called “Sha...

  3. Understanding why an active video game intervention did not improve motor skill and physical activity in children with developmental coordination disorder: A quantity or quality issue?

    Science.gov (United States)

    Howie, Erin K; Campbell, Amity C; Abbott, Rebecca A; Straker, Leon M

    2017-01-01

    Active video games (AVGs) have been identified as a novel strategy to improve motor skill and physical activity in clinical populations. A recent cross-over randomized trial found AVGs to be ineffective at improving motor skill and physical activity in the home-environment for children with or at-risk for developmental coordination disorder (DCD). The study purpose was to better understand why the intervention had been ineffective by examining the quantity and quality of AVG play during an AVG intervention for children with or at-risk for DCD. Participants (n=21, ages 9-12) completed the 16 week AVG intervention. Detailed quantitative and qualitative data were systematically triangulated to obtain the quantity of exposure (AVG exposure over time, patterns of exposure) and quality of use (game selection, facilitators and barriers to play). The median AVG dose (range 30-35min/day) remained relatively stable across the intervention and met the prescribed dose. Play quality was impacted by game selection, difficulty playing games, lack of time, illness, technical difficulties and boredom. The ineffectiveness of a home-based AVG intervention may be due to quality of play. Strategies to improve the quality of game play may help realize the potential benefits of AVGs as a clinical tool for children with DCD. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Coordination cycles

    Czech Academy of Sciences Publication Activity Database

    Steiner, Jakub

    -, č. 274 (2005), s. 1-26 ISSN 1211-3298 Institutional research plan: CEZ:AV0Z70850503 Keywords : coordination * crises * cycles and fluctuations Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp274.pdf

  5. Coordination cycles

    Czech Academy of Sciences Publication Activity Database

    Steiner, Jakub

    2008-01-01

    Roč. 63, č. 1 (2008), s. 308-327 ISSN 0899-8256 Institutional research plan: CEZ:AV0Z70850503 Keywords : global games * coordination * crises * cycles and fluctuations Subject RIV: AH - Economics Impact factor: 1.333, year: 2008

  6. Computational evaluation of sub-nanometer cluster activity of singly exposed copper atom with various coordinative environment in catalytic CO{sub 2} transformation

    Energy Technology Data Exchange (ETDEWEB)

    Shanmugam, Ramasamy [Department of Chemistry, Thiagarajar College, Madurai, Tamilnadu 625 009 (India); National Center for Catalysis Research, Indian Institute of Technology Madras, Chennai, Tamilnadu 600 036 (India); Thamaraichelvan, Arunachalam [Faculty of Allied Health Sciences, Chettinad Hospital & Research Institute, Kelambakkam, Tamilnadu 603 103 (India); Ganesan, Tharumeya Kuppusamy [Department of Chemistry, The American College, Madurai, Tamilnadu 625 002 (India); Viswanathan, Balasubramanian, E-mail: bvnathan@iitm.ac.in [National Center for Catalysis Research, Indian Institute of Technology Madras, Chennai, Tamilnadu 600 036 (India)

    2017-02-28

    Highlights: • On interaction with adsorbate CO{sub 2,} the adsorbent changes its configuration around the metal. • Electron transfer is faster in low coordinative environment of Cu. • CO formation is more favorable on Cu sites with even coordination number. • Cu at coordination number two has a over potential of −0.35 V. - Abstract: Metal cluster, at sub-nanometer level has a unique property in the activation of small molecules, in contrast to that of bulk surface. In the present work, singly exposed active site of copper metal cluster at sub-nanometer level was designed to arrive at the energy minimised configurations, binding energy, electrostatic potential map, frontier molecular orbitals and partial density of states. The ab initio molecular dynamics was carried out to probe the catalytic nature of the cluster. Further, the stability of the metal cluster and its catalytic activity in the electrochemical reduction of CO{sub 2} to CO were evaluated by means of computational hydrogen electrode via calculation of the free energy profile using DFT/B3LYP level of theory in vacuum. The activity of the cluster is ascertained from the fact that the copper atom, present in a two coordinative environment, performs a more selective conversion of CO{sub 2} to CO at an applied potential of −0.35 V which is comparatively lower than that of higher coordinative sites. The present study helps to design any sub-nano level metal catalyst for electrochemical reduction of CO{sub 2} to various value added chemicals.

  7. Advances in Neutron Activation Analysis of Large Objects with Emphasis on Archaeological Examples. Results of a Coordinated Research Project

    International Nuclear Information System (INIS)

    2018-03-01

    This publication is a compilation of the main results and findings of an IAEA coordinated research project (CRP). In particular, it discusses an innovative variation of neutron activation analysis (NAA) known as large sample NAA (LSNAA). There is no other way to measure the bulk mass fractions of the elements present in a large sample (up to kilograms in mass) non-destructively. Examples amenable to LSNAA include irregularly shaped archaeological artefacts, excavated rock samples, large samples of assorted ore, and finished products, such as nuclear reactor components. The CRP focused primarily on the application of LSNAA in the areas of archaeology and geology; however it was also open for further exploration in other areas such as industry and life sciences as well as in basic research. The CRP contributed to establish the validation of the methodology, and, in particular, it provided an opportunity for developing trained manpower. The specific objectives of this CRP were to: i) Validate and optimize the experimental procedures for LSNAA applications in archaeology and geology; ii) Identify the needs for development or upgrade of the neutron irradiation facility for irradiation of large samples; iii) Develop and standardize data acquisition and data analysis systems; iv) Harmonize and standardize data collection from facilities with similar kind of instrumentation for further analysis and benchmarking. Advantages of LSNAA applications, limitations and scientific and technological requirements are described in this publication, which serves as a reference of interest not only to the NAA experts, research reactor personnel, and those considering this technique, but also to various stakeholders and users such as researchers, industrialists, environmental and legal experts, and administrators.

  8. Analysis and co-ordination of the activities concerning gasification of biomass. Summary country report, Denmark and Norway

    International Nuclear Information System (INIS)

    Stoholm, P.; Olsen, A.

    1996-11-01

    The analysis summarises the coordination of activities concerning the gasification of biomass in Denmark and Norway. The total quantity of available biomass for energy production in Denmark corresponds to ca. 115 PJ of which ca. 40% is utilized - and this constitutes ca. 6% of the country's total energy consumption. The resulting energy from biomass is currently mostly used for heating purposes utilizing small wood/straw household or farm stoves in addition to ca. 100 district heating systems. There is a tendency to use biomass fuels for electric power production as in the case of all major waste incineration plants and about 10 fully or partly wood/straw-fired cogeneration plants which are found within the range of 2 -20 MWe. A table shows details of all Danish biomass gasification plants and information is given on the types of biomass, under the titles of residue products and energy crops, most relevant to energy production in Denmark. Data is presented on the consumption of renewable energy in Denmark, recalculated in fuel equivalents, and Danish national energy policy and related legislation are described. Information on Norway's use of biomass as fuel is given under the headings of primary consumption, biomass sources and use, legislation, and brief evaluations of commercial gasification plants, pilot and demonstration plants, and laboratory plants and studies. It has recently been decided to speed up the development of small-scale gasification plants for combined heat and electricity production using biomass as fuel in Denmark. Total Norwegian energy consumption is 25% higher than Denmark's, and biomass fuels cover only 3.6% of this. (ARW) 32 refs

  9. An evaluation of knowledge, attitude, and practice of institutional ethics committee members from eastern India regarding ethics committee functioning and pharmacovigilance activities conducted during clinical trials: A pilot study

    Directory of Open Access Journals (Sweden)

    Subhrojyoti Bhowmick

    2014-01-01

    Full Text Available Purpose of study: The vital responsibility of Institutional Ethics Committee (IEC members is to ensure the safety of the subjects participating in clinical trials. Hence, it is essential for IEC members to be aware of the common pharmacovigilance strategies followed during clinical trials. However, the information about the knowledge, attitude, and practice of IEC members regarding the pharmacovigilance activities followed during clinical trials is scarce worldwide, especially in India. Hence, this cross-sectional study was designed to assess the knowledge, attitude, and practice of IEC members of 10 hospitals of Kolkata, India. Materials and Methods: A cross-sectional study using a self-administered, validated questionnaire was conducted among 10 hospitals (five government and five corporate hospitals in Kolkata conducting active clinical research and having functional Ethics Committees (ECs in the month of September-November, 2012. An IEC approval was taken for this study. Two reminders were given to all EC members through telephone/e-mail for completion and returning of the forms. The filled in forms were returned to their respective Member Secretaries, from whom authors′ collected the forms. Data were analyzed using SPSS version 16.0 software and MS-Excel 2007. Categorical data were analyzed using Chi-square test and a P < 0.05 was considered statistically significant. Results: Out of the 100 distributed questionnaires, 40 were returned of which 10 were not filled properly. Overall awareness regarding different pharmacovigilance terminologies and activities among EC members from nonmedical background (71.43% was found to be more than that of the medical members (68.75%, though the figure was not statistically significant. Majority of the members (75% felt that EC should decide compensation in case of a serious adverse event. Conclusion: The present study signifies that there is a low level of awareness in IEC members of Kolkata regarding

  10. Maximizing policy learning in international committees

    DEFF Research Database (Denmark)

    Nedergaard, Peter

    2007-01-01

    , this article demonstrates that valuable lessons can be learned about policy learning, in practice and theoretically, by analysing the cooperation in the OMC committees. Using the Advocacy Coalition Framework as the starting point of analysis, 15 hypotheses on policy learning are tested. Among other things......In the voluminous literature on the European Union's open method of coordination (OMC), no one has hitherto analysed on the basis of scholarly examination the question of what contributes to the learning processes in the OMC committees. On the basis of a questionnaire sent to all participants......, it is concluded that in order to maximize policy learning in international committees, empirical data should be made available to committees and provided by sources close to the participants (i.e. the Commission). In addition, the work in the committees should be made prestigious in order to attract well...

  11. IAEA co-ordinated research programme on the transport of low specific activity materials and surface contaminated objects

    International Nuclear Information System (INIS)

    Gray, I.L.S.

    2000-01-01

    The International Atomic Energy Agency (IAEA) prepares regulations for the safe transport of radioactive material, and periodically revised editions of these are published. These regulations are adopted by individual countries across the world and by international organisations concerned with transport. Whilst it is desirable to have a stable framework of regulatory requirements, there is also a need to take account of technical advances and operational experience and revise the regulations. From time to time Co-ordinated Research Programmes (CRP) are established to investigate particular areas of the regulations that are giving concern. In 1996 the IAEA Standing Advisory Group on the Transport of Radioactive Material (SAGSTRAM) concluded that the requirements for classification, packaging and transport of low specific activity (LSA) material and surface contaminated objects (SCO) did not always have a strong radiation protection basis. Accordingly SAGSTRAM established a CRP with an overall objective to develop a dose-based approach for establishing LSA/SCO requirements. Six countries are participating in this CRP. Brazil, Canada, France, Germany, United Kingdom and United States. Each country is carrying out work that is outlined in agreements with the IAEA, with the work aimed at meeting the specific objective of the agreement and also contributing to achieving the overall objective of the CRP. Completion of the CRP usually involves the preparation of an IAEA TECDOC by a Consultant Services Meeting (CSM), and this TECDOC will summarise the work performed under the CRP and include any recommendations made by the CRP. Following the establishment of the CRP in 1997, the first Research Co-ordination Meeting (RCM) was held in December 1997. The second RCM was held in March 1999, with the final RCM planned for the end of 2000. The work being carried out by Brazil and Canada is focused upon the transport of uranium and thorium ores, and is a mixture of theoretical and

  12. Federal interagency radiation policy coordination

    International Nuclear Information System (INIS)

    Young, A.L.

    1984-01-01

    The author discusses Federal interagency radiation policy coordination. The Committee on Interagency Radiation Research and Policy Coordination (CIRRPC) is explained as being dedicated to the success and forward motion of enhanced radiation research and policy coordination. Both CIRRPC and the Science Panel are staffed with Federal employees. Their expertise includes many and various radiation disciplines including cytogenetics, dosimetry, epidemiology, genetics, health physics, nuclear medicine, radiology, radiation carcinogenesis, and risk assessment. Ten scientific and technical issues in their preliminary order are presented: radioepidemiological tables; de minimis radiation levels; radon progeny health effects; occupational exposure registry; measurement, recording, and control of radiation; food irradiation; use of radiation in science, industry, and medicine; nonionizing radiation; and remedial actions

  13. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    Overview From a technical perspective, CMS has been in “beam operation” state since 6th November. The detector is fully closed with all components operational and the magnetic field is normally at the nominal 3.8T. The UXC cavern is normally closed with the radiation veto set. Access to UXC is now only possible during downtimes of LHC. Such accesses must be carefully planned, documented and carried out in agreement with CMS Technical Coordination, Experimental Area Management, LHC programme coordination and the CCC. Material flow in and out of UXC is now strictly controlled. Access to USC remains possible at any time, although, for safety reasons, it is necessary to register with the shift crew in the control room before going down.It is obligatory for all material leaving UXC to pass through the underground buffer zone for RP scanning, database entry and appropriate labeling for traceability. Technical coordination (notably Stephane Bally and Christoph Schaefer), the shift crew and run ...

  14. Report on the activities of the ASME-NQA Committee Working Group on Quality Assurance Requirements for Research and Development, April 1990 to August 1991

    Energy Technology Data Exchange (ETDEWEB)

    Dronkers, J.J.

    1991-09-01

    This report transmits to the public eye the activities of the American Society of Mechanical Engineers-Nuclear Quality Assurance (ASME-NQA) Committee Working Group on Quality Assurance Requirements for Research and Development. The appendix lists the members of this group as of August 1991. The report covers a period of 17 months. The working group met eight times in this period, and much intellectual ground was traversed. There was seldom agreement on the nature of the task, but there was no doubt as to its urgency. The task was how to adapt the nuclear quality assurance standard, the NQA-1, to research and development work. 1 fig., 7 tabs.

  15. Co-ordinated Evaluation of Plutonium-239 in the Resonance Region - A report by the Working Party on International Nuclear Data Evaluation Co-operation of the NEA Nuclear Science Committee

    International Nuclear Information System (INIS)

    De Saint Jean, Cyrille; Noguere, Gilles; Peneliau, Yannick; Bernard, David; Serot, Olivier; McKnight, Richard D.; Leal, Luiz Carlos; Derrien, Herve; Kahler, Albert C.

    2014-04-01

    The Working Party on International Nuclear Data Evaluation Co-operation (WPEC) has been established under the aegis of the OECD/NEA Nuclear Science Committee (NSC) to promote the exchange of information on nuclear data evaluations, validation and related topics. Its aim is also to provide a framework for co-operative activities between the members of the major nuclear data evaluation projects. This includes the possible exchange of scientists in order to encourage co-operation. Requirements for experimental data resulting from this activity are compiled. The WPEC determines common criteria for evaluated nuclear data files with a view to assessing and improving the quality and completeness of evaluated data. The parties to the project are: BROND (Russian Federation), ENDF (United States), JENDL (Japan) and JEFF (other NEA Data Bank member countries), as well as CENDL (China) in close co-operation with the Nuclear Data Section of the International Atomic Energy Agency (IAEA). This report has been issued by the WPEC Subgroup 34 with a view to solving a general discrepancy when calculating criticality benchmarks with plutonium, using the most recent evaluated data libraries. This international effort enabled the delivery of a single set of resonance parameters up to 2.5 keV. The large fluctuations of the prompt neutron multiplicities were correctly reproduced with a phenomenological decomposition of the multiplicity that involved the two-step (n,γf) process. Performances of the new 239 Pu evaluation were tested over a broad set of integral data (ICSBEP, mock-up experiments performed in the CEA facilities and in power reactors). An overall good agreement was achieved between the calculations and the experimental results. The international effort performed in the framework of this Subgroup enabled delivery of a single set of resonance parameters up to 2.5 keV able to provide good C/E results over a broad set of integral data. The resonance analysis has been performed

  16. 75 FR 27703 - Humboldt Resource Advisory Committee (RAC)

    Science.gov (United States)

    2010-05-18

    ... Community Self-Determination Act (Pub. L. 110- 343) and in compliance with the Federal Advisory Committee... Federal Official and RAC Coordinator roles; (5) selection of RAC Chair; (6) next meeting agenda, location...

  17. [Management committees in health services: an empirical study].

    Science.gov (United States)

    Cecilio, Luiz Carlos de Oliveira

    2010-03-01

    The aim of the article, based on field data collected from a continuing education program for primary health clinic administrators, was to analyze the functioning of a health service management strategy called "management committees". Different meanings and operational modalities emerged in the committees. Various antimonies appeared in the way the committees operate (autonomy versus heteronomy, reproduction of "instituted" versus "instituting" processes, and communicative versus instrumental reasoning), thus reflecting the level of complexity in this management mechanism. Healthcare provision per se by the clinics only appeared occasionally on the committees' agenda, which mainly focused on administrative issues. The article suggests that further research is needed on the coordinator's involvement in the field of forces constituting the management committee, besides developing pedagogical strategies to support the clinic coordinators and health teams in building the committees. The primary data were submitted to an epistemological discussion anchored in the idea of double hermeneutics, multiple validation of research results, and the relationship between theory and practice.

  18. The Maize MID-COMPLEMENTING ACTIVITY homolog CELL NUMBER REGULATOR13/NARROW ODD DWARF, coordinates organ growth and tissue patterning

    Science.gov (United States)

    Organogenesis occurs from cell division, expansion and differentiation. How these cellular processes are coordinated remains elusive. The maize leaf provides an excellent system to study cellular differentiation because it has several different tissues and cell types. The narrow odd dwarf (nod) mut...

  19. Two coordination polymers based on semicarbazone Schiff base and azide: synthesis, crystal structure, electrochemistry, magnetic properties and biological activity

    Czech Academy of Sciences Publication Activity Database

    Shaabani, B.; Khandar, A.A.; Dušek, Michal; Pojarová, Michaela; Mahmoudi, F.; Feher, A.; Kajňaková, M.

    2013-01-01

    Roč. 66, č. 5 (2013), s. 748-762 ISSN 0095-8972 Grant - others:AV ČR(CZ) AP0701 Program:Akademická prémie - Praemium Academiae Institutional support: RVO:68378271 Keywords : Schiff bases * semicarbazone * coordination polymer * structure analyses Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 2.224, year: 2013

  20. Synthesis, Structural Characterization and Catalytic Activity of A Cu(II Coordination Polymer Constructed from 1,4-Phenylenediacetic Acid and 2,2’-Bipyridine

    Directory of Open Access Journals (Sweden)

    Wang Li-Hua

    2017-04-01

    Full Text Available In order to study the catalytic activity of Cu(II coordination polymer material, a novel 1D chained Cu(II coordination polymer material, [CuL(bipy(H2O5]n (A1 (H2L = 1,4-phenylenediacetic acid, bipy = 2,2’-bipyridine, has been prepared by the reaction of 1,4-phenylenediacetic acid, 2,2’-bipyridine, Cu(CH3COO2·H2O and NaOH. The composition of A1 was determined by elemental analysis, IR spectra and single crystal X-ray diffraction. The results of characterization show that each Cu(II atom adopts six-coordination and forms a distorted octahedral configuration. The catalytic activity and reusability of A1 catalyst for A3 coupling reaction of benzaldehyde, piperidine, and phenylacetylene have been investigated. And the results show that the Cu(II complex catalyst has good catalytic activity with a maximum yield of 54.3% and stability. Copyright © 2017 BCREC GROUP. All rights reserved Received: 21st October 2016; Revised: 17th November 2016; Accepted: 22nd November 2016 How to Cite: Li-Hua, W., Lei, L., Xin, W. (2017. Synthesis, Structural Characterization and Catalytic Activity of A Cu(II Coordination Polymer Constructed from 1,4-Phenylenediacetic Acid and 2,2’-Bipyridine. Bulletin of Chemical Reaction Engineering & Catalysis, 12 (1: 113-118 (doi:10.9767/bcrec.12.1.735.113-118 Permalink/DOI: http://dx.doi.org/10.9767/bcrec.12.1.735.113-118

  1. 75 FR 18145 - Eastern Arizona Counties Resource Advisory Committee

    Science.gov (United States)

    2010-04-09

    ... DEPARTMENT OF AGRICULTURE Forest Service Eastern Arizona Counties Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Eastern Arizona Counties Resource... Rivera, Coordinator, Eastern Arizona Counties Resource Advisory Committee, c/o Forest Service, USDA, P.O...

  2. Activities of working party on 'Subcritical core of accelerator-driven system' under the research committee on reactor physics of AESJ and JAERI

    International Nuclear Information System (INIS)

    Iwasaki, T.; Tsujimoto, K.; Nishihara, K.; Kitamura, Y.

    2004-01-01

    The Research Committee on Reactor Physics under the Atomic Energy Society of Japan and the Japan Atomic Energy Research Inst. organized the working party (ADS-WP) on S ubcritical Core of Accelerator-Driven System . The ADS-WP investigated reactor physics of subcriticality from the viewpoint of the accelerator driven system (ADS) since subcriticality has been almost studied from the viewpoint of critical safety. The working party was set in July 2001 and it worked for two years. The activities of the ADS-WP are (Work-I) theory of subcriticality, (Work-II) benchmark of subcritical core, (Work-III) setting of subcriticality level of ADS and (Work-JAO monitoring of subcriticality. These activities clarified about the important issues related to the subcriticality or the subcritical core from the wide ranges of theory, analysis, calculation, design and monitoring for ADS. The activities were already summarized and the report will be published in March 2004. (authors)

  3. Coordinating controls

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1986-07-15

    While physics Laboratories are having to absorb cuts in resources, the machines they rely on are becoming more and more complex, requiring increasingly sophisticated systems. Rather than being a resourceful engineer or physicist able to timber together solutions in his 'backyard', the modern controls specialist has become a professional in his own right. Because of possible conflicts between increasing sophistication on one hand and scarcer resources on the other, there was felt a need for more contacts among controls specialists to exchange experiences, coordinate development and discuss 'family problems', away from meetings where the main interest is on experimental physics.

  4. Coordinated unbundling

    DEFF Research Database (Denmark)

    Timmermans, Bram; Zabala-Iturriagagoitia, Jon Mikel

    2013-01-01

    Public procurement for innovation is a matter of using public demand to trigger innovation. Empirical studies have demonstrated that demand-based policy instruments can be considered to be a powerful tool in stimulating innovative processes among existing firms; however, the existing literature has...... not focused on the role this policy instrument can play in the promotion of (knowledge-intensive) entrepreneurship. This paper investigates this link in more detail and introduces the concept of coordinated unbundling as a strategy that can facilitate this purpose. We also present a framework on how...

  5. Coordinating controls

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    While physics Laboratories are having to absorb cuts in resources, the machines they rely on are becoming more and more complex, requiring increasingly sophisticated systems. Rather than being a resourceful engineer or physicist able to timber together solutions in his 'backyard', the modern controls specialist has become a professional in his own right. Because of possible conflicts between increasing sophistication on one hand and scarcer resources on the other, there was felt a need for more contacts among controls specialists to exchange experiences, coordinate development and discuss 'family problems', away from meetings where the main interest is on experimental physics

  6. Dimensions of Organizational Coordination

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt; Aldewereld, Huib; Dignum, Virginia

    2013-01-01

    be supported to include organizational objectives and constraints into their reasoning processes by considering two alternatives: agent reasoning and middleware regulation. We show how agents can use an organizational specification to achieve organizational objectives by delegating and coordinating...... their activities with other agents in the society, using the GOAL agent programming language and the OperA organizational model....

  7. TECHNICAL COORDINATION

    CERN Multimedia

    A. Ball

    2010-01-01

    Operational Experience At the end of the first full-year running period of LHC, CMS is established as a reliable, robust and mature experiment. In particular common systems and infrastructure faults accounted for <0.6 % CMS downtime during LHC pp physics. Technical operation throughout the entire year was rather smooth, the main faults requiring UXC access being sub-detector power systems and rack-cooling turbines. All such problems were corrected during scheduled technical stops, in the shadow of tunnel access needed by the LHC, or in negotiated accesses or access extensions. Nevertheless, the number of necessary accesses to the UXC averaged more than one per week and the technical stops were inevitably packed with work packages, typically 30 being executed within a few days, placing a high load on the coordination and area management teams. It is an appropriate moment for CMS Technical Coordination to thank all those in many CERN departments and in the Collaboration, who were involved in CMS techni...

  8. Diversity of activity participation determines bone mineral content in the lower limbs of pre-pubertal children with developmental coordination disorder.

    Science.gov (United States)

    Fong, S S M; Vackova, D; Choi, A W M; Cheng, Y T Y; Yam, T T T; Guo, X

    2018-04-01

    This study examined the relationships between activity participation and bone mineralization in children with developmental coordination disorder. Limited participation in physical, recreational, social, and skill-based and self-improvement activities contributed to lower bone mineral content. For improved bone health, these children should participate in a variety of activities, not only physical activities. Limited activity participation in children with developmental coordination disorder (DCD) may have a negative impact on bone mineral accrual. The objectives of this study were to compare bone mineralization and activity participation patterns of pre-pubertal children with DCD and those with typical development, and to determine the association between activity participation patterns and bone mineralization in children with DCD. Fifty-two children with DCD (mean age = 7.51 years) and 61 children with typical development (mean age = 7.22 years) participated in the study. Appendicular and total body (less head) bone mineral content (BMC) and bone mineral density (BMD) were evaluated by a whole-body dual-energy X-ray absorptiometry scan. Activity participation patterns were assessed using the Children's Assessment of Participation and Enjoyment (CAPE) questionnaire. Children with DCD had lower appendicular and total body BMCs and BMDs than children with typical development overall (p accounting for the effects of age, sex, height, lean mass, and fat mass, the total activity diversity score remained independently associated with leg BMC in children with DCD, explaining 5.1% of the variance (p = 0.030). However, the physical activity diversity score was no longer associated with leg BMC (p = 0.090). Diversity of activity participation and bone mineralization were lower in pre-pubertal children with DCD. Decreased total activity participation diversity was a contributing factor to lower BMC in the legs of children with DCD.

  9. Brain Oscillatory and Hemodynamic Activity in a Bimanual Coordination Task Following Transcranial Alternating Current Stimulation (tACS): A Combined EEG-fNIRS Study.

    Science.gov (United States)

    Berger, Alisa; Pixa, Nils H; Steinberg, Fabian; Doppelmayr, Michael

    2018-01-01

    Motor control is associated with synchronized oscillatory activity at alpha (8-12 Hz) and beta (12-30 Hz) frequencies in a cerebello-thalamo-cortical network. Previous studies demonstrated that transcranial alternating current stimulation (tACS) is capable of entraining ongoing oscillatory activity while also modulating motor control. However, the modulatory effects of tACS on both motor control and its underlying electro- and neurophysiological mechanisms remain ambiguous. Thus, the purpose of this study was to contribute to gathering neurophysiological knowledge regarding tACS effects by investigating the after-effects of 10 Hz tACS and 20 Hz tACS at parietal brain areas on bimanual coordination and its concurrent oscillatory and hemodynamic activity. Twenty-four right-handed healthy volunteers (12 females) aged between 18 and 30 ( M = 22.35 ± 3.62) participated in the study and performed a coordination task requiring bimanual movements. Concurrent to bimanual motor training, participants received either 10 Hz tACS, 20 Hz tACS or a sham stimulation over the parietal cortex (at P3/P4 electrode positions) for 20 min via small gel electrodes (3,14 cm 2 Ag/AgCl, amperage = 1 mA). Before and three time-points after tACS (immediately, 30 min and 1 day), bimanual coordination performance was assessed. Oscillatory activities were measured by electroencephalography (EEG) and hemodynamic changes were examined using functional near-infrared spectroscopy (fNIRS). Improvements of bimanual coordination performance were not differently between groups, thus, no tACS-specific effect on bimanual coordination performance emerged. However, physiological measures during the task revealed significant increases in parietal alpha activity immediately following 10 Hz tACS and 20 Hz tACS which were accompanied by significant decreases of Hboxy concentration in the right hemispheric motor cortex compared to the sham group. Based on the physiological responses, we conclude that t

  10. Brain Oscillatory and Hemodynamic Activity in a Bimanual Coordination Task Following Transcranial Alternating Current Stimulation (tACS: A Combined EEG-fNIRS Study

    Directory of Open Access Journals (Sweden)

    Alisa Berger

    2018-04-01

    Full Text Available Motor control is associated with synchronized oscillatory activity at alpha (8–12 Hz and beta (12–30 Hz frequencies in a cerebello-thalamo-cortical network. Previous studies demonstrated that transcranial alternating current stimulation (tACS is capable of entraining ongoing oscillatory activity while also modulating motor control. However, the modulatory effects of tACS on both motor control and its underlying electro- and neurophysiological mechanisms remain ambiguous. Thus, the purpose of this study was to contribute to gathering neurophysiological knowledge regarding tACS effects by investigating the after-effects of 10 Hz tACS and 20 Hz tACS at parietal brain areas on bimanual coordination and its concurrent oscillatory and hemodynamic activity. Twenty-four right-handed healthy volunteers (12 females aged between 18 and 30 (M = 22.35 ± 3.62 participated in the study and performed a coordination task requiring bimanual movements. Concurrent to bimanual motor training, participants received either 10 Hz tACS, 20 Hz tACS or a sham stimulation over the parietal cortex (at P3/P4 electrode positions for 20 min via small gel electrodes (3,14 cm2 Ag/AgCl, amperage = 1 mA. Before and three time-points after tACS (immediately, 30 min and 1 day, bimanual coordination performance was assessed. Oscillatory activities were measured by electroencephalography (EEG and hemodynamic changes were examined using functional near-infrared spectroscopy (fNIRS. Improvements of bimanual coordination performance were not differently between groups, thus, no tACS-specific effect on bimanual coordination performance emerged. However, physiological measures during the task revealed significant increases in parietal alpha activity immediately following 10 Hz tACS and 20 Hz tACS which were accompanied by significant decreases of Hboxy concentration in the right hemispheric motor cortex compared to the sham group. Based on the physiological responses, we conclude that

  11. Workforce Investment Act: Coordination between TANF Programs and One-Stop Centers Is Increasing, but Challenges Remain. Statement of Sigurd R. Nilsen, Director, Education, Workforce, and Income Security Issues [to the] Subcommittee on 21st Century Competitiveness, Committee on Education and the Workforce, House of Representatives.

    Science.gov (United States)

    Nilsen, Sigurd R.

    The General Accounting Office assessed the extent to which states were coordinating their Temporary Assistance for Needy Families (TANF) services with their one-stop centers. Data were gathered through the following activities: (1) an autumn 2001 survey of workforce development agency officials in all 50 states and a similar survey conducted in…

  12. International Assistance for Low-Emission Development Planning: Coordinated Low Emissions Assistance Network (CLEAN) Inventory of Activities and Tools--Preliminary Trends

    Energy Technology Data Exchange (ETDEWEB)

    Cox, S.; Benioff, R.

    2011-05-01

    The Coordinated Low Emissions Assistance Network (CLEAN) is a voluntary network of international practitioners supporting low-emission planning in developing countries. The network seeks to improve quality of support through sharing project information, tools, best practices and lessons, and by fostering harmonized assistance. CLEAN has developed an inventory to track and analyze international technical support and tools for low-carbon planning activities in developing countries. This paper presents a preliminary analysis of the inventory to help identify trends in assistance activities and tools available to support developing countries with low-emission planning.

  13. Ebselen protects against behavioral and biochemical toxicities induced by 3-nitropropionic acid in rats: correlations between motor coordination, reactive species levels, and succinate dehydrogenase activity.

    Science.gov (United States)

    Wilhelm, Ethel A; Bortolatto, Cristiani F; Jesse, Cristiano R; Luchese, Cristiane

    2014-12-01

    The protective effect of ebselen was investigated against 3-nitropropionic acid (3-NP)-induced behavioral and biochemical toxicities in rats. Ebselen (10 or 25 mg/kg, intragastrically) was administered to rats 30 min before 3-NP (20 mg/kg, intraperitoneally) once a day for a period of 4 days. Locomotor activity, motor coordination, and body weight gain were determined. The striatal content of reactive oxygen species (ROS), reduced glutathione (GSH), ascorbic acid (AA), and protein carbonyl as well as catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione-S-transferase (GST) activities was determined 24 h after the last dose of 3-NP. Na(+)/ K(+)-ATPase, succinate dehydrogenase (SDH), and δ-aminolevulinic dehydratase (δ-ALA-D) activities were also determined. The results demonstrated that ebselen at a dose of 25 mg/kg, but not at 10 mg/kg, protected against (1) a decrease in locomotor activity, motor coordination impairment, and body weight loss; (2) striatal oxidative damage, which was characterized by an increase in ROS levels, protein carbonyl content, and GR activity, an inhibition of CAT and GPx activities, and a decrease in GSH levels; and (3) an inhibition of SDH and Na(+)/K(+)-ATPase activities, induced by 3-NP. GST activity and AA levels were not modified by ebselen or 3-NP. Ebselen was not effective against the inhibition of δ-ALA-D activity induced by 3-NP. The results revealed a significant correlation between SDH activity and ROS levels, and SDH activity and latency to fall (rotarod test). The present study highlighted the protective effect of ebselen against 3-NP-induced toxicity in rats.

  14. 78 FR 76627 - Health Information Technology Standards Committee Advisory Meeting: Notice of Meeting

    Science.gov (United States)

    2013-12-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Information Technology Standards Committee Advisory Meeting: Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology... committee of the Office of the National Coordinator for Health Information Technology (ONC). These meeting...

  15. Co-ordinated research project on use of nuclear and related analytical techniques in studying human health impacts of toxic elements consumed through foodstuffs contaminated by industrial activities. Report on the first research co-ordination meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The overall objective of the Co-ordinated research project is to provide a scientific basis for better assessment of selected pollutants in the food chain with a view to elucidating their impacts on human health and nutrition. Results of this study will enhance the existing body of knowledge and can be used to develop preventive strategies. Specific objectve: To determine the extent to which toxic element levels in food are affected by surrounding industrial activities and to assess potential human exposure from the consumption of such foodstuffs. EXPECTED RESEARCH OUTPUTS (RESULTS): Harmonized protocols and procedures for sampling and analyses; ? Compiled results for toxic element levels and their average daily dietary intake (ADDI) / dietary intake; Evaluated toxic element exposure levels based on biological indicators (where applicable); Publications of the study results in an IAEA TECDOC, and in peer-reviewed journals by participants. ACTION PLAN (ACTIVITIES) a. Core research activities: 1 Identification of the study areas and population groups. 2 Collection of information on food consumption patterns of the population groups under study (e.g. through questionnaires). 3 Development of harmonized protocols and validation of analytical methodologies in compliance with ISO/IEC 17025. 4 Collection and analysis of food samples, and estimation of the dietary intake. 5 Collection and analysis of biological indicators where applicable. 6 Evaluation of possible relationships between human exposures and biological indicators for the pollutants studied. 4b. Supplementary activities: ? Speciation studies of pollutants. ? Comparison of present and previous data on relevant parameters. ? Possible production and distribution of laboratory intercomparison samples. 7. Recommendations for nuclear analytical techniques ? Nuclear analytical technique (NAT) such as INAA, PIXE, PIGE, XRF should be the primary technique of analysis; Instrumental neutron activation analysis (INAA

  16. 75 FR 21629 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-04-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the National Coordinator for Health Information Technology HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee...

  17. Cysteine Addition Promotes Sulfide Production and 4-Fold Hg(II)-S Coordination in Actively Metabolizing Escherichia coli.

    Science.gov (United States)

    Thomas, Sara A; Gaillard, Jean-François

    2017-04-18

    The bacterial uptake of mercury(II), Hg(II), is believed to be energy-dependent and is enhanced by cysteine in diverse species of bacteria under aerobic and anaerobic conditions. To gain insight into this Hg(II) biouptake pathway, we have employed X-ray absorption spectroscopy (XAS) to investigate the relationship between exogenous cysteine, cellular metabolism, cellular localization, and Hg(II) coordination in aerobically respiring Escherichia coli (E. coli). We show that cells harvested in exponential growth phase consistently display mixtures of 2-fold and 4-fold Hg(II) coordination to sulfur (Hg-S 2 and Hg-S 4 ), with added cysteine enhancing Hg-S 4 formation. In contrast, cells in stationary growth phase or cells treated with a protonophore causing a decrease in cellular ATP predominantly contain Hg-S 2 , regardless of cysteine addition. Our XAS results favor metacinnabar (β-HgS) as the Hg-S 4 species, which we show is associated with both the cell envelope and cytoplasm. Additionally, we observe that added cysteine abiotically oxidizes to cystine and exponentially growing E. coli degrade high cysteine concentrations (100-1000 μM) into sulfide. Thermodynamic calculations confirm that cysteine-induced sulfide biosynthesis can promote the formation of dissolved and particulate Hg(II)-sulfide species. This report reveals new complexities arising in Hg(II) bioassays with cysteine and emphasizes the need for considering changes in chemical speciation as well as growth stage.

  18. Computational evaluation of sub-nanometer cluster activity of singly exposed copper atom with various coordinative environment in catalytic CO2 transformation

    Science.gov (United States)

    Shanmugam, Ramasamy; Thamaraichelvan, Arunachalam; Ganesan, Tharumeya Kuppusamy; Viswanathan, Balasubramanian

    2017-02-01

    Metal cluster, at sub-nanometer level has a unique property in the activation of small molecules, in contrast to that of bulk surface. In the present work, singly exposed active site of copper metal cluster at sub-nanometer level was designed to arrive at the energy minimised configurations, binding energy, electrostatic potential map, frontier molecular orbitals and partial density of states. The ab initio molecular dynamics was carried out to probe the catalytic nature of the cluster. Further, the stability of the metal cluster and its catalytic activity in the electrochemical reduction of CO2 to CO were evaluated by means of computational hydrogen electrode via calculation of the free energy profile using DFT/B3LYP level of theory in vacuum. The activity of the cluster is ascertained from the fact that the copper atom, present in a two coordinative environment, performs a more selective conversion of CO2 to CO at an applied potential of -0.35 V which is comparatively lower than that of higher coordinative sites. The present study helps to design any sub-nano level metal catalyst for electrochemical reduction of CO2 to various value added chemicals.

  19. Co-ordinate changes in enzymes of fatty acid synthesis, activation and esterification in rabbit mammary gland druing pregnancy and lactation.

    Science.gov (United States)

    Short, V J; Brindley, D N; Dils, R

    1977-01-01

    1. The activities of fatty acid synthetase, acyl-CoA synthetase, glycerol phosphate acyltransferase and phosphatidate phosphatase were measured in the mammary glands of rabbits from day 16 of pregnancy to day 15 of post partum. 2. There were significant correlations between the increases in activities of these enzymes during this period. This was the case whether the activities were expressed per mg of homogenate protein, per g wet wt. of tissue or per total wet weight of the whole glands. The only exception was the lack of correlation between the activities of fatty acid synthetase and of phosphatidate phosphatase per g wet wt. of tissue. 3. These co-ordinate increases are discussed in relation to the changes which occur in fatty acid metabolism in the mammary gland during pregnancy and lactation. PMID:192226

  20. Effect of Mesoporous Chitosan Action and Coordination on the Catalytic Activity of Mesoporous Chitosan-Grafted Cobalt Tetrakis(p-SulfophenylPorphyrin for Ethylbenzene Oxidation

    Directory of Open Access Journals (Sweden)

    Guan Huang

    2018-05-01

    Full Text Available To simulate the active site cavity structure function and axial coordination of cytochrome P-450 enzymes, mesoporous chitosan(mesp-CTS was used as a scaffold for a meso-sized cavity to immobilize cobalt tetrakis(p-sulphophenylporphyrin chloride(Co TPPS. Immobilization was achieved via an acid–base reaction and axial coordination of the H2N-C group to the Co ion in Co TPPS, thus forming the biomimetic catalyst Co TPPS/mesp-CTS. Several approaches, including scanning electron microscopy (SEM, the Brunauer–Emmett–Teller (BETtechnique, Fourier transform infrared (FT-IR spectroscopy, ultraviolet-visible (UV-vis spectroscopy, thermogravimetric and differential scanning calorimetry (TG-DSC, and X-ray photoelectron spectroscopy (XPS, were used to characterize the grafted catalyst. The catalytic performance of Co TPPS/mesp-CTS in ethylbenzene oxidation without any solvents and additives was investigated. The results showed that only 0.96 × 10 mol of Co TPPS grafted onto mesp-CTS could be recycled three times for 200 mL of ethylbenzene oxidation, with an average yield of 44.6% and selectivity of 68.8%. The highly efficient catalysis can be attributed to promotion by mesp-CTS, including the effect of the mesoporous structure and the axial coordination to the Co ion in Co TPPS. This biomimetic methodology provides a method for clean production of acetophenone via ethylbenzene oxidation.

  1. Cd (II) and holodirected lead (II) 3D-supramolecular coordination polymers based on nicotinic acid: Structure, fluorescence property and photocatalytic activity

    Science.gov (United States)

    Etaiw, Safaa El-din H.; Abd El-Aziz, Dina M.; Marie, Hassan; Ali, Elham

    2018-05-01

    Two new supramolecular coordination polymers namely {[Cd(NA)2(H2O)]}, SCP 1 and {[Pb(NA)2]}, SCP 2, (NA = nicotinate ligand) were synthesized by self-assembly method and structurally characterized by different analytical and spectroscopic methods. Single-crystal X-ray diffraction showed that SCP 1 extend in three dimensions containing bore structure where the 3D- network is constructed via interweaving zigzag chains. The Cd atom coordinates to (O4N2) atoms forming distorted-octahedral configuration. The structure of SCP 2 extend down the projection of the b-axis creating parallel zigzag 1D-chains connected by μ2-O2 atoms and H-bonds forming a holodirected lead (II) hexagonal bi-pyramid configuration. SCP 2 extend to 3D-network via coordinate and hydrogen bonds. The thermal stability, photoluminescence properties, photocatalytic activity for the degradation of methylene blue dye (MB) under UV-irradiation and sunlight irradiation were also studied.

  2. 77 FR 71169 - Smart Grid Advisory Committee Meeting

    Science.gov (United States)

    2012-11-29

    ... cybersecurity coordination and the NIST Smart Grid Program Plan. The agenda may change to accommodate Committee business. The final agenda will be posted on the Smart Grid Web site at http://www.nist.gov/smartgrid... receive presentations on cybersecurity coordination and the NIST Smart Grid Program Plan. The agenda may...

  3. Different ankle muscle coordination patterns and co-activation during quiet stance between young adults and seniors do not change after a bout of high intensity training.

    Science.gov (United States)

    Donath, Lars; Kurz, Eduard; Roth, Ralf; Zahner, Lukas; Faude, Oliver

    2015-03-04

    Available evidence suggests that young adults and seniors use different strategies to adjust for increasing body sway during quiet standing. Altered antagonist muscle co-activation and different ankle muscle coordination patterns may account for this finding. Consequently, we aimed at addressing whether aging leads to changes in neuromuscular coordination patterns as well as co-activation during quiet stance. We additionally investigated whether a bout of high intensity interval training additionally alters these patterns. Twenty healthy seniors (age: 70 ± 4 y) and twenty young adults (age: 27 ± 3 y) were enrolled in the present study. In between the testing procedures, four consecutive high-intensity intervals of 4 min duration at a target exercise intensity of 90 to 95% HRmax were completed on a treadmill. The total center of pressure (COP) path length displacement served as standing balance performance outcome. In order to assess ankle muscle coordination patterns, amplitude ratios (AR) were calculated for each muscle (e.g. tibialis anterior (TA) [%] = (TA × 100)/(gastrocnemius medialis (GM) + soleus (SOL) + peroneus longus (PL) + TA). The co-activation was calculated for the SOL and TA muscles computing the co-activation index (CAI = 2 × TA/TA + SOL). Seniors showed an inverted ankle muscle coordination pattern during single limb stance with eyes open (SLEO), compared to young adults (rest: GM, S: 15 ± 8% vs Y: 24 ± 9%; p = 0.03; SOL, S: 27 ± 14% vs Y: 37 ± 18%; p = 0.009; TA, S: 31 ± 13% vs Y: 13 ± 7%; p = 0.003). These patterns did not change after a high-intensity training session. A moderate correlation between amplitude ratios of the TA-contribution and postural sway was observed for seniors during SLEO (r = 0.61). Ankle co-activation was twofold elevated in seniors compared to young adults during SLEO (p Seniors with decreased postural control showed higher TA

  4. Report of the Long-Range Planning Committee

    International Nuclear Information System (INIS)

    1984-01-01

    This is the final report of the Long-Range Planning Committee of the Lawrence Livermore National Laboratory. It describes the make-up, purpose, working assumptions, and activities of the Committee and discusses the work done by the Committee on defense matters, energy, a number of additional topics, and future long-range planning activities

  5. Nuclear Safety Research Review Committee

    International Nuclear Information System (INIS)

    Todreas, N.E.

    1990-01-01

    The Nuclear Safety Research Review Committee has had a fundamental difficulty because of the atmosphere that has existed since it was created. It came into existence at a time of decreasing budgets. For any Committee the easiest thing is to tell the Director what additional to do. That does not really help him a lot in this atmosphere of reduced budgets which he reviewed for you on Monday. Concurrently the research arm of Nuclear Regulatory Commission has recognized that the scope of its activity needed to be increased rather than decreased. In the last two-and-a-half-year period, human factors work was reinstated, radiation and health effects investigations were reinvigorated, research in the waste area was given significant acceleration. Further, accident management came into being, and the NRC finally got back into the TMI-2 area. So with all of those activities being added to the program at the same time that the research budget was going down, the situation has become very strained. What that leads to regarding Committee membership is a need for technically competent generalists who will be able to sit as the Division Directors come in, as the contractors come in, and sort the wheat from the chaff. The Committee needs people who are interested in and have a broad perspective on what regulatory needs are and specifically how safety research activities can contribute to them. The author summarizes the history of the Committee, the current status, and plans for the future

  6. 78 FR 40098 - Emerging Technology and Research Advisory Committee;

    Science.gov (United States)

    2013-07-03

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Emerging Technology and Research Advisory Committee; Notice of Partially Closed Meeting The Emerging Technology and Research Advisory Committee (ETRAC... Assistant Secretary for Export Administration on emerging technology and research activities, including...

  7. Report of the BC [British Columbia] Citizens Advisory Committee on Oil Spill Prevention and Response

    International Nuclear Information System (INIS)

    1992-01-01

    The British Columbia Citizens Advisory Committee on Oil Spill Prevention and Response was established in 1991 to advise the provincial government of public concerns over oil spill prevention, preparedness, and response. The Committee also monitors provincial and joint provincial/western USA initiatives in the area. The Committee notes that the volume of oil tanker traffic through navigationally risky passages along the British Columbia coast is large and that prevention is the most useful method in dealing with oil spills. Committee concerns are summarized in the areas of government committment, design and construction of oil tankers and barges, oil spill issues related to ports, the Low Point Terminal proposal, waste oil collection and disposal, spill response capability, the Strait of Georgia Oil Spill Response Information System, the use of volunteer auxiliaries and the Youth Corps in oil spill response, wildlife rescue and rehabilitation, coordination of response activities, and the future of the Committee. Recommendations to the government are made with respect to the aforementioned areas of concern

  8. Studies on coordination chemistry and biological activities of a nitrogen-sulfur donor ligand with lighter and heavier metal ions

    International Nuclear Information System (INIS)

    Tarafder, M.T.H.; Asmadi, A.; Talib, S.M.S.; Ali, A.M.; Crouse, K.A.

    1999-05-01

    Complexes of S-benzyldithiocarbazate (SBDTC) with lighter and heavier metals, viz., Cr(III), Fe(III), Sb(III), Zr(IV), Th(IV), and U(VI) have been prepared and characterized by elemental analyses, conductivity measurements, and spectral studies. The complexes were all prepared in alkaline media with the compositions of [Cr(SBDTCA) 3 ], [Fe(SBDTCA) 3 ], [Sb(SBDTCA) 3 ], [Sb(SBDTCA) 2 CI.H 2 O], [Zr(O)(SBDTCA) 2 .H 2 O], [Th(SBDTCA)(NO 3 ) 3 .H 2 O)], and [U(O) 2 (SBDTCA) 2 ]. The complexes were all hexa-coordinated with bidentate, uninegative chelation of the ligand. [Fe(SBDTCA) 3 ], [Sb(SBDTCA) 3 ] and [Sb(SBDTCA) 2 CI.H 2 O] were strongly effective against bacteria, Pseudomonas aeruginosa and Bacillus cereus giving clear inhibition zones. The compounds were poor antifungal. (author)

  9. Drought-Induced Effects on Nitrate Reductase Activity and mRNA and on the Coordination of Nitrogen and Carbon Metabolism in Maize Leaves1

    Science.gov (United States)

    Foyer, Christine H.; Valadier, Marie-Hélène; Migge, Andrea; Becker, Thomas W.

    1998-01-01

    Maize (Zea mays L.) plants were grown to the nine-leaf stage. Despite a saturating N supply, the youngest mature leaves (seventh position on the stem) contained little NO3− reserve. Droughted plants (deprived of nutrient solution) showed changes in foliar enzyme activities, mRNA accumulation, photosynthesis, and carbohydrate and amino acid contents. Total leaf water potential and CO2 assimilation rates, measured 3 h into the photoperiod, decreased 3 d after the onset of drought. Starch, glucose, fructose, and amino acids, but not sucrose (Suc), accumulated in the leaves of droughted plants. Maximal extractable phosphoenolpyruvate carboxylase activities increased slightly during water deficit, whereas the sensitivity of this enzyme to the inhibitor malate decreased. Maximal extractable Suc phosphate synthase activities decreased as a result of water stress, and there was an increase in the sensitivity to the inhibitor orthophosphate. A correlation between maximal extractable foliar nitrate reductase (NR) activity and the rate of CO2 assimilation was observed. The NR activation state and maximal extractable NR activity declined rapidly in response to drought. Photosynthesis and NR activity recovered rapidly when nutrient solution was restored at this point. The decrease in maximal extractable NR activity was accompanied by a decrease in NR transcripts, whereas Suc phosphate synthase and phosphoenolpyruvate carboxylase mRNAs were much less affected. The coordination of N and C metabolism is retained during drought conditions via modulation of the activities of Suc phosphate synthase and NR commensurate with the prevailing rate of photosynthesis. PMID:9576798

  10. 78 FR 56952 - Notice of Meetings: Public Meetings of the National Science and Technology Council; Committee on...

    Science.gov (United States)

    2013-09-16

    ... Science and Technology Council; Committee on Technology; Nanoscale Science, Engineering, and Technology Subcommittee; National Nanotechnology Coordination Office AGENCY: Office of Science and Technology Policy. ACTION: Notice of public meetings. SUMMARY: The National Nanotechnology Coordination Office (NNCO), on...

  11. Rationale, design and methods for a randomised and controlled trial of the impact of virtual reality games on motor competence, physical activity, and mental health in children with developmental coordination disorder

    Directory of Open Access Journals (Sweden)

    Straker Leon M

    2011-08-01

    Full Text Available Abstract Background A healthy start to life requires adequate motor development and physical activity participation. Currently 5-15% of children have impaired motor development without any obvious disorder. These children are at greater risk of obesity, musculoskeletal disorders, low social confidence and poor mental health. Traditional electronic game use may impact on motor development and physical activity creating a vicious cycle. However new virtual reality (VR game interfaces may provide motor experiences that enhance motor development and lead to an increase in motor coordination and better physical activity and mental health outcomes. VR games are beginning to be used for rehabilitation, however there is no reported trial of the impact of these games on motor coordination in children with developmental coordination disorder. Methods This cross-over randomised and controlled trial will examine whether motor coordination is enhanced by access to active electronic games and whether daily activity, attitudes to physical activity and mental health are also enhanced. Thirty children aged 10-12 years with poor motor coordination (≤ 15th percentile will be recruited and randomised to a balanced ordering of 'no active electronic games' and 'active electronic games'. Each child will participate in both conditions for 16 weeks, and be assessed prior to participation and at the end of each condition. The primary outcome is motor coordination, assessed by kinematic and kinetic motion analysis laboratory measures. Physical activity and sedentary behaviour will be assessed by accelerometry, coordination in daily life by parent report questionnaire and attitudes to physical activity, self-confidence, anxiety and depressed mood will be assessed by self report questionnaire. A sample of 30 will provide a power of > 0.9 for detecting a 5 point difference in motor coordination on the MABC-2 TIS scale (mean 17, sd = 5. Discussion This is the first trial to

  12. Rationale, design and methods for a randomised and controlled trial of the impact of virtual reality games on motor competence, physical activity, and mental health in children with developmental coordination disorder.

    Science.gov (United States)

    Straker, Leon M; Campbell, Amity C; Jensen, Lyn M; Metcalf, Deborah R; Smith, Anne J; Abbott, Rebecca A; Pollock, Clare M; Piek, Jan P

    2011-08-18

    A healthy start to life requires adequate motor development and physical activity participation. Currently 5-15% of children have impaired motor development without any obvious disorder. These children are at greater risk of obesity, musculoskeletal disorders, low social confidence and poor mental health. Traditional electronic game use may impact on motor development and physical activity creating a vicious cycle. However new virtual reality (VR) game interfaces may provide motor experiences that enhance motor development and lead to an increase in motor coordination and better physical activity and mental health outcomes. VR games are beginning to be used for rehabilitation, however there is no reported trial of the impact of these games on motor coordination in children with developmental coordination disorder. This cross-over randomised and controlled trial will examine whether motor coordination is enhanced by access to active electronic games and whether daily activity, attitudes to physical activity and mental health are also enhanced. Thirty children aged 10-12 years with poor motor coordination (≤ 15th percentile) will be recruited and randomised to a balanced ordering of 'no active electronic games' and 'active electronic games'. Each child will participate in both conditions for 16 weeks, and be assessed prior to participation and at the end of each condition. The primary outcome is motor coordination, assessed by kinematic and kinetic motion analysis laboratory measures. Physical activity and sedentary behaviour will be assessed by accelerometry, coordination in daily life by parent report questionnaire and attitudes to physical activity, self-confidence, anxiety and depressed mood will be assessed by self report questionnaire. A sample of 30 will provide a power of > 0.9 for detecting a 5 point difference in motor coordination on the MABC-2 TIS scale (mean 17, sd = 5). This is the first trial to examine the impact of new virtual reality games on

  13. Structure and Heme-Independent Peroxidase Activity of a Fully-Coordinated Mononuclear Mn(II) Complex with a Schiff-Base Tripodal Ligand Containing Three Imidazole Groups

    Energy Technology Data Exchange (ETDEWEB)

    Sarkar, Shuranjan; Lee, Hong In [Kyungpook National University, Daegu (Korea, Republic of); Moon, Do Hyun [Pohang Accelerator Laboratory, Pohang (Korea, Republic of); Lah, Myoung Soo [Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2010-11-15

    New complex [Mn(II)H{sub 1.5}L]{sub 2}[Mn(II)H{sub 3}L]{sub 2}(ClO{sub 4}){sub 5}·3H{sub 2}O, where H{sub 3}L is tris{2-(4-imidazolyl)methyliminoethyl} amine (imtren), has been prepared by reacting manganese(II) perchlorate hexahydrate with the imtren ligand in methanol. X-ray crystallographic study revealed that the imtren ligand hexadentately binds to Mn(II) ion through the three Schiff-base imine N atoms and three imidazole N atoms with a distorted octahedral geometry, and the apical tertiary amine N atom of the ligand pseudo-coordinates to Mn(II), forming overall a pseudo-seven coordination environment. The hydrogen-bonds between imidazole and imidazolate of [Mn(II)H{sub 1.5}L]{sup 0.5+} complex ions are extended to build a 2D puckered network with trigonal voids. [Mn(II)H{sub 3}L]{sup 2+} complex ions constitutes another extended 2D puckered layer without hydrogen bonds. Two layers are wedged each other to constitute overall stack of the crystal. Peroxidase activity of complex 1 was examined by observing the oxidation of 2,2'-azinobis(3-ethylbenzothiazoline)- 6-sulfonic acid (ABTS) with hydrogen peroxide in the presence of complex 1. Generation of ABTS{sup +·} was observed by UV-vis and EPR spectroscopies, indicating that the complex 1, a fully-coordinated mononuclear Mn(II) complex with nitrogen-only ligand, has a heme-independent peroxidase activity.

  14. Coordination of hand shape.

    Science.gov (United States)

    Pesyna, Colin; Pundi, Krishna; Flanders, Martha

    2011-03-09

    The neural control of hand movement involves coordination of the sensory, motor, and memory systems. Recent studies have documented the motor coordinates for hand shape, but less is known about the corresponding patterns of somatosensory activity. To initiate this line of investigation, the present study characterized the sense of hand shape by evaluating the influence of differences in the amount of grasping or twisting force, and differences in forearm orientation. Human subjects were asked to use the left hand to report the perceived shape of the right hand. In the first experiment, six commonly grasped items were arranged on the table in front of the subject: bottle, doorknob, egg, notebook, carton, and pan. With eyes closed, subjects used the right hand to lightly touch, forcefully support, or imagine holding each object, while 15 joint angles were measured in each hand with a pair of wired gloves. The forces introduced by supporting or twisting did not influence the perceptual report of hand shape, but for most objects, the report was distorted in a consistent manner by differences in forearm orientation. Subjects appeared to adjust the intrinsic joint angles of the left hand, as well as the left wrist posture, so as to maintain the imagined object in its proper spatial orientation. In a second experiment, this result was largely replicated with unfamiliar objects. Thus, somatosensory and motor information appear to be coordinated in an object-based, spatial-coordinate system, sensitive to orientation relative to gravitational forces, but invariant to grasp forcefulness.

  15. 1976 compilation of national nuclear data committees

    International Nuclear Information System (INIS)

    1977-01-01

    This list of currently existing National Nuclear Data Committees, and their memberships, is published with the object of promoting the interaction and enhance the awareness of nuclear data activities in IAEA Member States. The following Member States have indicated the existence of a nuclear data committee in their countries: Bangladesh, Bolivia, Bulgaria, France, Hungary, India, Japan, Romania, Sweden, USSR, United Kingdom, USA, Yugoslavia

  16. Coordination polymers of Fe(iii) and Al(iii) ions with TCA ligand: distinctive fluorescence, CO2 uptake, redox-activity and oxygen evolution reaction.

    Science.gov (United States)

    Dhara, Barun; Sappati, Subrahmanyam; Singh, Santosh K; Kurungot, Sreekumar; Ghosh, Prasenjit; Ballav, Nirmalya

    2016-04-28

    Fe and Al belong to different groups in the periodic table, one from the p-block and the other from the d-block. In spite of their different groups, they have the similarity of exhibiting a stable 3+ oxidation state. Here we have prepared Fe(iii) and Al(iii) based coordination polymers in the form of metal-organic gels with the 4,4',4''-tricarboxyltriphenylamine (TCA) ligand, namely Fe-TCA and Al-TCA, and evaluated some important physicochemical properties. Specifically, the electrical conductivity, redox-activity, porosity, and electrocatalytic activity (oxygen evolution reaction) of the Fe-TCA system were noted to be remarkably higher than those of the Al-TCA system. As for the photophysical properties, almost complete quenching of the fluorescence originating from TCA was observed in case of the Fe-TCA system, whereas for the Al-TCA system a significant retention of fluorescence with red-shifted emission was observed. Quantum mechanical calculations based on density functional theory (DFT) were performed to unravel the origin of such discriminative behaviour of these coordination polymer systems.

  17. Measuring inconsistency in research ethics committee review.

    Science.gov (United States)

    Trace, Samantha; Kolstoe, Simon Erik

    2017-11-28

    The review of human participant research by Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) is a complex multi-faceted process that cannot be reduced to an algorithm. However, this does not give RECs/ IRBs permission to be inconsistent in their specific requirements to researchers or in their final opinions. In England the Health Research Authority (HRA) coordinates 67 committees, and has adopted a consistency improvement plan including a process called "Shared Ethical Debate" (ShED) where multiple committees review the same project. Committee reviews are compared for consistency by analysing the resulting minutes. We present a description of the ShED process. We report an analysis of minutes created by research ethics committees participating in two ShED exercises, and compare them to minutes produced in a published "mystery shopper" exercise. We propose a consistency score by defining top themes for each exercise, and calculating the ratio between top themes and total themes identified by each committee for each ShED exercise. Our analysis highlights qualitative differences between the ShED 19, ShED 20 and "mystery shopper" exercises. The quantitative measure of consistency showed only one committee across the three exercises with more than half its total themes as top themes (ratio of 0.6). The average consistency scores for the three exercises were 0.23 (ShED19), 0.35 (ShED20) and 0.32 (mystery shopper). There is a statistically significant difference between the ShED 19 exercise, and the ShED 20 and mystery shopper exercises. ShED exercises are effective in identifying inconsistency between ethics committees and we describe a scoring method that could be used to quantify this. However, whilst a level of inconsistency is probably inevitable in research ethics committee reviews, studies must move beyond the ShED methodology to understand why inconsistency occurs, and what an acceptable level of inconsistency might be.

  18. Temporally coordinated spiking activity of human induced pluripotent stem cell-derived neurons co-cultured with astrocytes.

    Science.gov (United States)

    Kayama, Tasuku; Suzuki, Ikuro; Odawara, Aoi; Sasaki, Takuya; Ikegaya, Yuji

    2018-01-01

    In culture conditions, human induced-pluripotent stem cells (hiPSC)-derived neurons form synaptic connections with other cells and establish neuronal networks, which are expected to be an in vitro model system for drug discovery screening and toxicity testing. While early studies demonstrated effects of co-culture of hiPSC-derived neurons with astroglial cells on survival and maturation of hiPSC-derived neurons, the population spiking patterns of such hiPSC-derived neurons have not been fully characterized. In this study, we analyzed temporal spiking patterns of hiPSC-derived neurons recorded by a multi-electrode array system. We discovered that specific sets of hiPSC-derived neurons co-cultured with astrocytes showed more frequent and highly coherent non-random synchronized spike trains and more dynamic changes in overall spike patterns over time. These temporally coordinated spiking patterns are physiological signs of organized circuits of hiPSC-derived neurons and suggest benefits of co-culture of hiPSC-derived neurons with astrocytes. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Nanorods of a new metal-biomolecule coordination polymer showing novel bidirectional electrocatalytic activity and excellent performance in electrochemical sensing.

    Science.gov (United States)

    Yang, Jiao; Zhou, Bo; Yao, Jie; Jiang, Xiao-Qing

    2015-05-15

    Metal organic coordination polymers (CPs), as most attractive multifunctional materials, have been studied extensively in many fields. However, metal-biomolecule CPs and CPs' electrochemical properties and applications were studied much less. We focus on this topic aiming at electrochemical biosensors with excellent performance and high biocompatibility. A new nanoscaled metal-biomolecule CP, Mn-tyr, containing manganese and tyrosine, was synthesized hydrothermally and characterized by various techniques, including XRD, TEM, EDS, EDX mapping, elemental analysis, XPS, and IR. Electrode modified with Mn-tyr showed novel bidirectional electrocatalytic ability toward both reduction and oxidation of H2O2, which might be due to Mn. With the assistance of CNTs, the sensing performance of Mn-tyr/CNTs/GCE was improved to a much higher level, with high sensitivity of 543 mA mol(-1) L cm(-2) in linear range of 1.00×10(-6)-1.02×10(-4) mol L(-1), and detection limit of 3.8×10(-7) mol L(-1). Mn-tyr/CNTs/GCE also showed fast response, high selectivity, high steadiness and reproducibility. The excellent performance implies that the metal-biomolecule CPs are promising candidates for using in enzyme-free electrochemical biosensing. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. The Audit Committee. AGB Effective Committee Series

    Science.gov (United States)

    Staisloff, Richard L.

    2011-01-01

    This publication is part of an Association of Governing Boards of Universities and Colleges (AGB) series devoted to strengthening the role of key standing committees of governing boards. While there is no optimum committee system for institutions of higher education, certain principles, practices, and procedures prevail. The best practices…