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  1. Effet du compost à base de Calotropis procera (Aiton) W.T. Aiton sur ...

    African Journals Online (AJOL)

    Objectifs: Une étude à base de compost de Calotropis procera a été menée afin de mesurer l'effet sur la production de l'arachide sur de sols pauvres. Méthodologie et résultats: L'essai a été conduit sur le site de Doyaba au niveau des zones marginales du Tchad avec la variété fleur 11 d'arachide (Arachis hypogaea L.) ...

  2. 14 Oxydation du phenol sur un catalyseur à base de Fer supporté ...

    African Journals Online (AJOL)

    AKA BOKO

    Oxydation du phenol sur un catalyseur à base de Fer supporté sur une argile marocaine. Noura LAHBABI1*, Zakia RAIS2, M. HAJJAJI 3 et S. KACIM3. 1 Laboratoire d'ingénierie des matériaux organométalliques et moléculaire. Faculté des. Sciences Dhar El Mehrez, Fès, Maroc. 2 Laboratoire d'analyses physico-chimiques ...

  3. Components of SurA required for outer membrane biogenesis in uropathogenic Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Kristin M Watts

    2008-10-01

    Full Text Available SurA is a periplasmic peptidyl-prolyl isomerase (PPIase and chaperone of Escherichia coli and other Gram-negative bacteria. In contrast to other PPIases, SurA appears to have a distinct role in chaperoning newly synthesized porins destined for insertion into the outer membrane. Previous studies have indicated that the chaperone activity of SurA rests in its "core module" (the N- plus C-terminal domains, based on in vivo envelope phenotypes and in vitro binding and protection of non-native substrates.In this study, we determined the components of SurA required for chaperone activity using in vivo phenotypes relevant to disease causation by uropathogenic E. coli (UPEC, namely membrane resistance to permeation by antimicrobials and maturation of the type 1 pilus usher FimD. FimD is a SurA-dependent, integral outer membrane protein through which heteropolymeric type 1 pili, which confer bladder epithelial binding and invasion capacity upon uropathogenic E. coli, are assembled and extruded. Consistent with prior results, the in vivo chaperone activity of SurA in UPEC rested primarily in the core module. However, the PPIase domains I and II were not expendable for wild-type resistance to novobiocin in broth culture. Steady-state levels of FimD were substantially restored in the UPEC surA mutant complemented with the SurA N- plus C-terminal domains. The addition of PPIase domain I augmented FimD maturation into the outer membrane, consistent with a model in which domain I enhances stability of and/or substrate binding by the core module.Our results confirm the core module of E. coli SurA as a potential target for novel anti-infective development.

  4. Kir6.2 activation by sulfonylurea receptors: a different mechanism of action for SUR1 and SUR2A subunits via the same residues

    Science.gov (United States)

    Principalli, Maria A; Dupuis, Julien P; Moreau, Christophe J; Vivaudou, Michel; Revilloud, Jean

    2015-01-01

    ATP-sensitive potassium channels (K-ATP channels) play a key role in adjusting the membrane potential to the metabolic state of cells. They result from the unique combination of two proteins: the sulfonylurea receptor (SUR), an ATP-binding cassette (ABC) protein, and the inward rectifier K+ channel Kir6.2. Both subunits associate to form a heterooctamer (4 SUR/4 Kir6.2). SUR modulates channel gating in response to the binding of nucleotides or drugs and Kir6.2 conducts potassium ions. The activity of K-ATP channels varies with their localization. In pancreatic β-cells, SUR1/Kir6.2 channels are partly active at rest while in cardiomyocytes SUR2A/Kir6.2 channels are mostly closed. This divergence of function could be related to differences in the interaction of SUR1 and SUR2A with Kir6.2. Three residues (E1305, I1310, L1313) located in the linker region between transmembrane domain 2 and nucleotide-binding domain 2 of SUR2A were previously found to be involved in the activation pathway linking binding of openers onto SUR2A and channel opening. To determine the role of the equivalent residues in the SUR1 isoform, we designed chimeras between SUR1 and the ABC transporter multidrug resistance-associated protein 1 (MRP1), and used patch clamp recordings on Xenopus oocytes to assess the functionality of SUR1/MRP1 chimeric K-ATP channels. Our results reveal that the same residues in SUR1 and SUR2A are involved in the functional association with Kir6.2, but they display unexpected side-chain specificities which could account for the contrasted properties of pancreatic and cardiac K-ATP channels. PMID:26416970

  5. The Sur7 Protein Regulates Plasma Membrane Organization and Prevents Intracellular Cell Wall Growth in Candida albicans

    OpenAIRE

    Alvarez, Francisco J.; Douglas, Lois M.; Rosebrock, Adam; Konopka, James B.

    2008-01-01

    The Candida albicans plasma membrane plays important roles in cell growth and as a target for antifungal drugs. Analysis of Ca-Sur7 showed that this four transmembrane domain protein localized to stable punctate patches, similar to the plasma membrane subdomains known as eisosomes or MCC that were discovered in S. cerevisiae. The localization of Ca-Sur7 depended on sphingolipid synthesis. In contrast to S. cerevisiae, a C. albicans sur7Δ mutant displayed defects in endocytosis and morphogenes...

  6. Du simple relevé de végétation à la gestion des données sur la biodiversité : problèmes liées à la construction d’une base de données sur la flore alpine

    Directory of Open Access Journals (Sweden)

    SPIEGELBERGER, Thomas

    2010-10-01

    Full Text Available À partir de l'exemple de constitution de la base de données FloRem sur la flore alpine, cet article nous présente ici les difficultés, les avantages et limites d'une telle base pour la valorisation de données de diversité végétale sur le long terme.

  7. Generalized image contrast enhancement technique based on the Heinemann contrast discrimination model

    Science.gov (United States)

    Liu, Hong; Nodine, Calvin F.

    1996-07-01

    This paper presents a generalized image contrast enhancement technique, which equalizes the perceived brightness distribution based on the Heinemann contrast discrimination model. It is based on the mathematically proven existence of a unique solution to a nonlinear equation, and is formulated with easily tunable parameters. The model uses a two-step log-log representation of luminance contrast between targets and surround in a luminous background setting. The algorithm consists of two nonlinear gray scale mapping functions that have seven parameters, two of which are adjustable Heinemann constants. Another parameter is the background gray level. The remaining four parameters are nonlinear functions of the gray-level distribution of the given image, and can be uniquely determined once the previous three are set. Tests have been carried out to demonstrate the effectiveness of the algorithm for increasing the overall contrast of radiology images. The traditional histogram equalization can be reinterpreted as an image enhancement technique based on the knowledge of human contrast perception. In fact, it is a special case of the proposed algorithm.

  8. Analyse de l'effet de la suréducation sur l'efficacité technique des ...

    African Journals Online (AJOL)

    de tire-au-flanc, et l'état de santé (Vroom 1964 ; Sheppard & Herrick 1972 ; ... impact négatif significatif de la suréducation sur la satisfaction au travail ; son ..... présence syndicale sur la performance financière de 250 entreprises américaines.

  9. La cooperación Sur-Sur agrícola argentina con África Subsahariana: una historia que comienza

    OpenAIRE

    Morasso, Carla

    2015-01-01

    [es] En la última década Argentina ha sido un actor dinámico de la cooperación Sur-Sur. Sus acciones se han dirigido principalmente hacia América Latina, pero también se han promovido los vínculos con Asia y África. El artículo analiza particularmente la cooperación Sur-Sur entre Argentina y países de África Subsahariana en materia de desarrollo agrícola en el período 2003-2013, donde se destacan los roles del Fondo Argentino de Cooperación Sur-Sur y Triangula...

  10. Unión del magreb, un caso de regionalismo Sur-Sur

    Directory of Open Access Journals (Sweden)

    SofianE Bouhdiba

    2009-01-01

    Full Text Available Se exploran brevemente las fuerzas y limitaciones de la Unión del Magreb (UMA como una experiencia de regionalismo Sur-Sur, en el marco de mayor extensión. Se plantea la necesidad de que la UMA redireccione sus intereses, estrategias y alianzas hacia el sur, puesto que se ha vuelto un instrumento de intercambios comerciales con la Unión Europea y un eje estratégico de lucha contra el terrorismo para Estados Unidos. Además se invita a la misma UMA a que considere los alcances de instituciones de integración en América Latina y Asia a fin de fortalecerse como bloque.

  11. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans.

    Science.gov (United States)

    Alvarez, Francisco J; Douglas, Lois M; Rosebrock, Adam; Konopka, James B

    2008-12-01

    The Candida albicans plasma membrane plays important roles in cell growth and as a target for antifungal drugs. Analysis of Ca-Sur7 showed that this four transmembrane domain protein localized to stable punctate patches, similar to the plasma membrane subdomains known as eisosomes or MCC that were discovered in S. cerevisiae. The localization of Ca-Sur7 depended on sphingolipid synthesis. In contrast to S. cerevisiae, a C. albicans sur7Delta mutant displayed defects in endocytosis and morphogenesis. Septins and actin were mislocalized, and cell wall synthesis was very abnormal, including long projections of cell wall into the cytoplasm. Several phenotypes of the sur7Delta mutant are similar to the effects of inhibiting beta-glucan synthase, suggesting that the abnormal cell wall synthesis is related to activation of chitin synthase activity seen under stress conditions. These results expand the roles of eisosomes by demonstrating that Sur7 is needed for proper plasma membrane organization and cell wall synthesis. A conserved Cys motif in the first extracellular loop of fungal Sur7 proteins is similar to a characteristic motif of the claudin proteins that form tight junctions in animal cells, suggesting a common role for these tetraspanning membrane proteins in forming specialized plasma membrane domains.

  12. The Sur7 Protein Regulates Plasma Membrane Organization and Prevents Intracellular Cell Wall Growth in Candida albicans

    Science.gov (United States)

    Alvarez, Francisco J.; Douglas, Lois M.; Rosebrock, Adam

    2008-01-01

    The Candida albicans plasma membrane plays important roles in cell growth and as a target for antifungal drugs. Analysis of Ca-Sur7 showed that this four transmembrane domain protein localized to stable punctate patches, similar to the plasma membrane subdomains known as eisosomes or MCC that were discovered in S. cerevisiae. The localization of Ca-Sur7 depended on sphingolipid synthesis. In contrast to S. cerevisiae, a C. albicans sur7Δ mutant displayed defects in endocytosis and morphogenesis. Septins and actin were mislocalized, and cell wall synthesis was very abnormal, including long projections of cell wall into the cytoplasm. Several phenotypes of the sur7Δ mutant are similar to the effects of inhibiting β-glucan synthase, suggesting that the abnormal cell wall synthesis is related to activation of chitin synthase activity seen under stress conditions. These results expand the roles of eisosomes by demonstrating that Sur7 is needed for proper plasma membrane organization and cell wall synthesis. A conserved Cys motif in the first extracellular loop of fungal Sur7 proteins is similar to a characteristic motif of the claudin proteins that form tight junctions in animal cells, suggesting a common role for these tetraspanning membrane proteins in forming specialized plasma membrane domains. PMID:18799621

  13. Nephrogenic systemic fibrosis and gadolinium-based contrast media

    DEFF Research Database (Denmark)

    Thomsen, Henrik S; Morcos, Sameh K; Almén, Torsten

    2012-01-01

    PURPOSE: To update the guidelines of the Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) on nephrogenic systemic fibrosis and gadolinium-based contrast media. AREAS COVERED: Topics reviewed include the history, clinical features and prevalence of neph...... guidelines regarding gadolinium contrast agents minimises the risk of NSF • Potential long-term harm from gadolinium accumulation in the body is discussed.......PURPOSE: To update the guidelines of the Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) on nephrogenic systemic fibrosis and gadolinium-based contrast media. AREAS COVERED: Topics reviewed include the history, clinical features and prevalence...... of nephrogenic systemic fibrosis and the current understanding of its pathophysiology. The risk factors for NSF are discussed and prophylactic measures are recommended. The stability of the different gadolinium-based contrast media and the potential long-term effects of gadolinium in the body have also been...

  14. Más allá de los mitos: análisis de la Cooperación Sur-Sur y Norte-Sur en el Ecuador. Sector Educación, período 2003- 2008

    OpenAIRE

    Escobar Sánchez, Wladimir Alexander

    2012-01-01

    La presente tesis de maestría analiza a la cooperación Norte-Sur y Sur-Sur como los dos principales modelos de funcionamiento de la cooperación hoy en día, a través de dos programas de ayuda internacional en el sector educación, en el período 2003-2008. El uno referente a la cooperación Norte-Sur, y el otro a la cooperación Sur-Sur. El propósito que presenta este trabajo académico es explicar a la cooperación internacional al desarrollo tomando en consideración a la teoría real...

  15. Étude sur l'entrepreneuriat dalit : Regard sur 25 % de la population ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude sur l'entrepreneuriat dalit : Regard sur 25 % de la population indienne. Cette étude, pilotée par Udit Raj, député du parlement indien, aide à mieux comprendre les contraintes que rencontrent les entrepreneurs dalits. Elle permettra de sonder 12 000 entrepreneurs dalits dans 14 états et de recueillir des données ...

  16. Generalized image contrast enhancement technique based on Heinemann contrast discrimination model

    Science.gov (United States)

    Liu, Hong; Nodine, Calvin F.

    1994-03-01

    This paper presents a generalized image contrast enhancement technique which equalizes perceived brightness based on the Heinemann contrast discrimination model. This is a modified algorithm which presents an improvement over the previous study by Mokrane in its mathematically proven existence of a unique solution and in its easily tunable parameterization. The model uses a log-log representation of contrast luminosity between targets and the surround in a fixed luminosity background setting. The algorithm consists of two nonlinear gray-scale mapping functions which have seven parameters, two of which are adjustable Heinemann constants. Another parameter is the background gray level. The remaining four parameters are nonlinear functions of gray scale distribution of the image, and can be uniquely determined once the previous three are given. Tests have been carried out to examine the effectiveness of the algorithm for increasing the overall contrast of images. It can be demonstrated that the generalized algorithm provides better contrast enhancement than histogram equalization. In fact, the histogram equalization technique is a special case of the proposed mapping.

  17. Étude du Partenariat de recherche sur l'influenza aviaire en Asie sur ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude du Partenariat de recherche sur l'influenza aviaire en Asie sur l'efficacité des mesures de lutte. L'influenza aviaire hautement pathogène (H5N1) est une grave maladie qui touche la volaille et contamine les êtres humains dans une faible proportion. L'Organisation mondiale de la santé croit que le virus pourrait subir ...

  18. Sur la plurifonctionnalité du discours direct

    OpenAIRE

    Cigada Sara

    2012-01-01

    La comparaison entre les résultats de nombreux travaux sur le dialogue dans le texte littéraire, sur l’attestation linguistique de la subjectivité, sur la fonction argumentative des émotions dans le discours et sur les effets de polyphonie, suggère que la structure sémiotique et linguistique du discours direct (DD) se trouve au croisement stratégique de plusieurs axes de la construction discursive. Nous étudions donc l’insertion du DD dans le discours (cf. Rosier 2008: Le discours rapporté en...

  19. Gd-HOPO Based High Relaxivity MRI Contrast Agents

    Energy Technology Data Exchange (ETDEWEB)

    Datta, Ankona; Raymond, Kenneth

    2008-11-06

    Tris-bidentate HOPO-based ligands developed in our laboratory were designed to complement the coordination preferences of Gd{sup 3+}, especially its oxophilicity. The HOPO ligands provide a hexadentate coordination environment for Gd{sup 3+} in which all he donor atoms are oxygen. Because Gd{sup 3+} favors eight or nine coordination, this design provides two to three open sites for inner-sphere water molecules. These water molecules rapidly exchange with bulk solution, hence affecting the relaxation rates of bulk water olecules. The parameters affecting the efficiency of these contrast agents have been tuned to improve contrast while still maintaining a high thermodynamic stability for Gd{sup 3+} binding. The Gd- HOPO-based contrast agents surpass current commercially available agents ecause of a higher number of inner-sphere water molecules, rapid exchange of inner-sphere water molecules via an associative mechanism, and a long electronic relaxation time. The contrast enhancement provided by these agents is at least twice that of commercial contrast gents, which are based on polyaminocarboxylate ligands.

  20. Gadolinium-based contrast agents in pediatric magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gale, Eric M.; Caravan, Peter [Massachusetts General Hospital, Harvard Medical School, Department of Radiology, The Martinos Center for Biomedical Imaging, Boston, MA (United States); Rao, Anil G. [Medical University of South Carolina, Department of Radiology and Radiological Science, Charleston, SC (United States); McDonald, Robert J. [College of Medicine, Mayo Clinic, Department of Radiology, Rochester, MN (United States); Winfeld, Matthew [University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (United States); Fleck, Robert J. [Cincinnati Children' s Hospital Medical Center, Department of Pediatric Radiology, Cincinnati, OH (United States); Gee, Michael S. [MassGeneral Hospital for Children, Harvard Medical School, Division of Pediatric Imaging, Department of Radiology, Boston, MA (United States)

    2017-05-15

    Gadolinium-based contrast agents can increase the accuracy and expediency of an MRI examination. However the benefits of a contrast-enhanced scan must be carefully weighed against the well-documented risks associated with administration of exogenous contrast media. The purpose of this review is to discuss commercially available gadolinium-based contrast agents (GBCAs) in the context of pediatric radiology. We discuss the chemistry, regulatory status, safety and clinical applications, with particular emphasis on imaging of the blood vessels, heart, hepatobiliary tree and central nervous system. We also discuss non-GBCA MRI contrast agents that are less frequently used or not commercially available. (orig.)

  1. Reconnaissance aveugle de codages OSTBC basée sur les propriétés matricielles des statistiques d'ordre 2.

    OpenAIRE

    Choqueuse , Vincent ,; Collin , Ludovic; Yao , Koffi Clément; Burel , Gilles

    2007-01-01

    International audience; La reconnaissance aveugle des paramètres d'une communication est une thématique importante dans le contexte des récepteurs auto-configurants et de la guerre électronique. Actuellement, peu de recherches se focalisent sur la reconnaissance aveugle du codage spatio-temporel utilisé dans les communications sans fils multi-émetteurs. Pour caractériser ces codages, nous proposons une nouvelle fonction de contraste basée sur des propriétés matricielles remarquables de statis...

  2. Extracellular gadolinium-based contrast media: An overview

    International Nuclear Information System (INIS)

    Bellin, Marie-France; Van Der Molen, Aart J.

    2008-01-01

    Increasing use is made of extracellular MRI contrast agents that alter the image contrast following intravenous administration; they predominantly shorten the T1 relaxation time of tissues. The degree and location of these changes provide substantial diagnostic information. However gadolinium-based contrast agents (Gd-CA) are not inert drugs. They may cause acute non-renal adverse reactions (e.g. anaphylactoid reactions), acute renal adverse reactions (e.g. contrast induced nephropathy), delayed adverse reactions (nephrogenic systemic fibrosis) and problems at the site of injection (e.g. local necrosis). This review describes the current status of Gd-CA, their mechanism of action, chemical structure, pharmacokinetics, dosage, elimination, nephrotoxicity and adverse events

  3. Extracellular gadolinium-based contrast media: An overview

    Energy Technology Data Exchange (ETDEWEB)

    Bellin, Marie-France [University Paris-Sud 11, Department of Radiology, University Hospital Paul-Brousse, AP-HP, 12, Avenue Paul Vaillant-Couturier, 94804 Villejuif Cedex (France)], E-mail: marie-france.bellin@pbr.aphp.fr; Van Der Molen, Aart J. [University Paris-Sud 11, Department of Radiology, University Hospital Paul-Brousse, AP-HP, 12, Avenue Paul Vaillant-Couturier, 94804 Villejuif Cedex (France)

    2008-05-15

    Increasing use is made of extracellular MRI contrast agents that alter the image contrast following intravenous administration; they predominantly shorten the T1 relaxation time of tissues. The degree and location of these changes provide substantial diagnostic information. However gadolinium-based contrast agents (Gd-CA) are not inert drugs. They may cause acute non-renal adverse reactions (e.g. anaphylactoid reactions), acute renal adverse reactions (e.g. contrast induced nephropathy), delayed adverse reactions (nephrogenic systemic fibrosis) and problems at the site of injection (e.g. local necrosis). This review describes the current status of Gd-CA, their mechanism of action, chemical structure, pharmacokinetics, dosage, elimination, nephrotoxicity and adverse events.

  4. Iodine-based contrast media, multiple myeloma and monoclonal gammopathies

    DEFF Research Database (Denmark)

    Stacul, Fulvio; Bertolotto, Michele; Thomsen, Henrik S

    2018-01-01

    OBJECTIVES: Many radiologists and clinicians still consider multiple myeloma (MM) and monoclonal gammopathies (MG) a contraindication for using iodine-based contrast media. The ESUR Contrast Media Safety Committee performed a systematic review of the incidence of post-contrast acute kidney injury...

  5. Altiplano Sur de Bolivia

    OpenAIRE

    Alvarez-Flores, Ricardo; Bommel, Pierre; Bourliaud, Jean; Chevarria Lazo, Marco; Cortes, Geneviève; Cruz, Pablo; Del Castillo, C.; Gasselin, Pierre; Joffre, Richard; Leger, Francois; Nina Laura, Juan Peter; Rambal, Serge; Rivière, Gilles; Tichit, Muriel; Tourrand, Jean-François

    2014-01-01

    Alimento de base de las poblaciones andinas desde hace milenios, la quinua se ha convertido hoy en un producto apreciado en el mercado internacional de alimentos dietéticos, orgánicos y equitativos. Este cambio lo iniciaron los mismos productores del Altiplano Sur de Bolivia hace aproximadamente unos 40 años. En medio de un desierto de altura, ellos lograron desarrollar una floreciente producción agrícola de exportación. Aunque cuentan con lucrativos nichos de mercado, los productores de quin...

  6. Iodine-based contrast media, multiple myeloma and monoclonal gammopathies: literature review and ESUR Contrast Media Safety Committee guidelines.

    Science.gov (United States)

    Stacul, Fulvio; Bertolotto, Michele; Thomsen, Henrik S; Pozzato, Gabriele; Ugolini, Donatella; Bellin, Marie-France; Bongartz, Georg; Clement, Olivier; Heinz-Peer, Gertraud; van der Molen, Aart; Reimer, Peter; Webb, Judith A W

    2018-02-01

    Many radiologists and clinicians still consider multiple myeloma (MM) and monoclonal gammopathies (MG) a contraindication for using iodine-based contrast media. The ESUR Contrast Media Safety Committee performed a systematic review of the incidence of post-contrast acute kidney injury (PC-AKI) in these patients. A systematic search in Medline and Scopus databases was performed for renal function deterioration studies in patients with MM or MG following administration of iodine-based contrast media. Data collection and analysis were performed according to the PRISMA statement 2009. Eligibility criteria and methods of analysis were specified in advance. Cohort and case-control studies reporting changes in renal function were included. Thirteen studies were selected that reported 824 iodine-based contrast medium administrations in 642 patients with MM or MG, in which 12 unconfounded cases of PC-AKI were found (1.6 %). The majority of patients had intravenous urography with high osmolality ionic contrast media after preparatory dehydration and purgation. MM and MG alone are not risk factors for PC-AKI. However, the risk of PC-AKI may become significant in dehydrated patients with impaired renal function. Hypercalcaemia may increase the risk of kidney damage, and should be corrected before contrast medium administration. Assessment for Bence-Jones proteinuria is not necessary. • Monoclonal gammopathies including multiple myeloma are a large spectrum of disorders. • In monoclonal gammopathy with normal renal function, PC-AKI risk is not increased. • Renal function is often reduced in myeloma, increasing the risk of PC-AKI. • Correction of hypercalcaemia is necessary in myeloma before iodine-based contrast medium administration. • Bence-Jones proteinuria assessment in myeloma is unnecessary before iodine-based contrast medium administration.

  7. Risk-Based Tailoring of the Verification, Validation, and Accreditation/Acceptance Processes (Adaptation fondee sur le risque, des processus de verification, de validation, et d’accreditation/d’acceptation)

    Science.gov (United States)

    2012-04-01

    AGARD doivent comporter la dénomination « RTO » ou « AGARD » selon le cas, suivi du numéro de série. Des informations analogues, telles que le titre ...MSG-054 Risk-Based Tailoring of the Verification, Validation, and Accreditation/ Acceptance Processes (Adaptation fondée sur le risque, des...MSG-054 Risk-Based Tailoring of the Verification, Validation, and Accreditation/ Acceptance Processes (Adaptation fondée sur le risque, des

  8. Contrast enhancement by lipid-based MRI contrast agents in mouse atherosclerotic plaques; a longitudinal study

    NARCIS (Netherlands)

    den Adel, Brigit; van der Graaf, Linda M.; Que, Ivo; Strijkers, Gustav J.; Löwik, Clemens W.; Poelmann, Robert E.; van der Weerd, Louise

    2013-01-01

    The use of contrast-enhanced MRI to enable in vivo specific characterization of atherosclerotic plaques is increasing. In this study the intrinsic ability of two differently sized gadolinium-based contrast agents to enhance atherosclerotic plaques in ApoE(-/-) mice was evaluated with MRI. We

  9. Bâle 3 : Quels impacts sur le financement des pays émergents ?

    OpenAIRE

    Figuet, Jean-Marc; Humblot, Thomas; Lahet, Delphine

    2013-01-01

    La persistance de crises bancaires démontre l'incapacité des établissements de crédit à s'autoréguler. De ce fait, le Comité de Bâle étend largement le périmètre de la nouvelle règlementation prudentielle. Sur la base de la littérature sur les déterminants des flux de capitaux transfrontières et d'un GMM système, cet article analyse l'impact potentiel de l'accord Bâle 3 sur les flux de capitaux bancaires provenant des banques de 16 pays industrialisés à destination d'un panel de 30 pays émerg...

  10. Field strength and dose dependence of contrast enhancement by gadolinium-based MR contrast agents

    International Nuclear Information System (INIS)

    Rinck, P.A.; Muller, R.N.

    1999-01-01

    The relaxivities r 1 and r 2 of magnetic resonance contrast agents and the T 1 relaxation time values of tissues are strongly field dependent. We present quantitative data and simulations of different gadolinium-based extracellular fluid contrast agents and the modulation of their contrast enhancement by the magnetic field to be able to answer the following questions: How are the dose and field dependences of their contrast enhancement? Is there an interrelationship between dose and field dependence? Should one increase or decrease doses at specific fields? Nuclear magnetic relaxation dispersion data were acquired for the following contrast agents: gadopentetate dimeglumine, gadoterate meglumine, gadodiamide injection, and gadoteridol injection, as well as for several normal and pathological human tissue samples. The magnetic field range stretched from 0.0002 to 4.7 T, including the entire clinical imaging range. The data acquired were then fitted with the appropriate theoretical models. The combination of the diamagnetic relaxation rates (R 1 = 1/T 1 and R 2 = 1/T 2 ) of tissues with the respective paramagnetic contributions of the contrast agents allowed the prediction of image contrast at any magnetic field. The results revealed a nearly identical field and dose-dependent increase of contrast enhancement induced by these contrast agents within a certain dose range. The target tissue concentration (TTC) was an important though nonlinear factor for enhancement. The currently recommended dose of 0.1 mmol/kg body weight seems to be a compromise close to the lower limits of diagnostically sufficient contrast enhancement for clinical imaging at all field strengths. At low field contrast enhancement might be insufficient. Adjustment of dose or concentration, or a new class of contrast agents with optimized relaxivity, would be a valuable contribution to a better diagnostic yield of contrast enhancement at all fields. (orig.)

  11. Grating-based X-ray phase contrast for biomedical imaging applications

    International Nuclear Information System (INIS)

    Pfeiffer, Franz; Willner, Marian; Chabior, Michael; Herzen, Julia; Helmholtz-Zentrum Geesthacht, Geesthacht; Auweter, Sigrid; Reiser, Maximilian; Bamberg, Fabian

    2013-01-01

    In this review article we describe the development of grating-based X-ray phase-contrast imaging, with particular emphasis on potential biomedical applications of the technology. We review the basics of image formation in grating-based phase-contrast and dark-field radiography and present some exemplary multimodal radiography results obtained with laboratory X-ray sources. Furthermore, we discuss the theoretical concepts to extend grating-based multimodal radiography to quantitative transmission, phase-contrast, and dark-field scattering computed tomography. (orig.)

  12. Visual Contrast Enhancement Algorithm Based on Histogram Equalization

    Science.gov (United States)

    Ting, Chih-Chung; Wu, Bing-Fei; Chung, Meng-Liang; Chiu, Chung-Cheng; Wu, Ya-Ching

    2015-01-01

    Image enhancement techniques primarily improve the contrast of an image to lend it a better appearance. One of the popular enhancement methods is histogram equalization (HE) because of its simplicity and effectiveness. However, it is rarely applied to consumer electronics products because it can cause excessive contrast enhancement and feature loss problems. These problems make the images processed by HE look unnatural and introduce unwanted artifacts in them. In this study, a visual contrast enhancement algorithm (VCEA) based on HE is proposed. VCEA considers the requirements of the human visual perception in order to address the drawbacks of HE. It effectively solves the excessive contrast enhancement problem by adjusting the spaces between two adjacent gray values of the HE histogram. In addition, VCEA reduces the effects of the feature loss problem by using the obtained spaces. Furthermore, VCEA enhances the detailed textures of an image to generate an enhanced image with better visual quality. Experimental results show that images obtained by applying VCEA have higher contrast and are more suited to human visual perception than those processed by HE and other HE-based methods. PMID:26184219

  13. Visual Contrast Enhancement Algorithm Based on Histogram Equalization

    Directory of Open Access Journals (Sweden)

    Chih-Chung Ting

    2015-07-01

    Full Text Available Image enhancement techniques primarily improve the contrast of an image to lend it a better appearance. One of the popular enhancement methods is histogram equalization (HE because of its simplicity and effectiveness. However, it is rarely applied to consumer electronics products because it can cause excessive contrast enhancement and feature loss problems. These problems make the images processed by HE look unnatural and introduce unwanted artifacts in them. In this study, a visual contrast enhancement algorithm (VCEA based on HE is proposed. VCEA considers the requirements of the human visual perception in order to address the drawbacks of HE. It effectively solves the excessive contrast enhancement problem by adjusting the spaces between two adjacent gray values of the HE histogram. In addition, VCEA reduces the effects of the feature loss problem by using the obtained spaces. Furthermore, VCEA enhances the detailed textures of an image to generate an enhanced image with better visual quality. Experimental results show that images obtained by applying VCEA have higher contrast and are more suited to human visual perception than those processed by HE and other HE-based methods.

  14. Adaptive radiotherapy based on contrast enhanced cone beam CT imaging

    International Nuclear Information System (INIS)

    Soevik, Aaste; Skogmo, Hege K.; Roedal, Jan; Lervaag, Christoffer; Eilertsen, Karsten; Malinen, Eirik

    2010-01-01

    Cone beam CT (CBCT) imaging has become an integral part of radiation therapy, with images typically used for offline or online patient setup corrections based on bony anatomy co-registration. Ideally, the co-registration should be based on tumor localization. However, soft tissue contrast in CBCT images may be limited. In the present work, contrast enhanced CBCT (CECBCT) images were used for tumor visualization and treatment adaptation. Material and methods. A spontaneous canine maxillary tumor was subjected to repeated cone beam CT imaging during fractionated radiotherapy (10 fractions in total). At five of the treatment fractions, CECBCT images, employing an iodinated contrast agent, were acquired, as well as pre-contrast CBCT images. The tumor was clearly visible in post-contrast minus pre-contrast subtraction images, and these contrast images were used to delineate gross tumor volumes. IMRT dose plans were subsequently generated. Four different strategies were explored: 1) fully adapted planning based on each CECBCT image series, 2) planning based on images acquired at the first treatment fraction and patient repositioning following bony anatomy co-registration, 3) as for 2), but with patient repositioning based on co-registering contrast images, and 4) a strategy with no patient repositioning or treatment adaptation. The equivalent uniform dose (EUD) and tumor control probability (TCP) calculations to estimate treatment outcome for each strategy. Results. Similar translation vectors were found when bony anatomy and contrast enhancement co-registration were compared. Strategy 1 gave EUDs closest to the prescription dose and the highest TCP. Strategies 2 and 3 gave EUDs and TCPs close to that of strategy 1, with strategy 3 being slightly better than strategy 2. Even greater benefits from strategies 1 and 3 are expected with increasing tumor movement or deformation during treatment. The non-adaptive strategy 4 was clearly inferior to all three adaptive strategies

  15. Agir sur la langue pour agir sur le monde : Micropolitiques linguistiques autogérées du genre dans les brochures libertaires

    OpenAIRE

    Abbou, Julie

    2015-01-01

    La dimension agissante de la langue sur le monde entraîne avec elle, comme un appel d'air, l'action sur la langue elle-même, et l'action sur la langue n'est jamais loin de se faire action politique. Les politiques linguistiques de féminisation en sont un exemple, où l'action politique se concentre sur la catégorisation du genre. Dans de nombreux cas, la politique linguistique se fait planification linguistique, cherchant de nouvelles normes. Dans de nombreux cas, mais pas toujours. Il existe ...

  16. CARACTERIZACIÓN DEL CONSUMO DE HORTALIZAS EN LAS FAMILIAS DEL SUR-SUR DE COSTA RICA

    Directory of Open Access Journals (Sweden)

    Alexis Villalobos-Monge

    2013-01-01

    Full Text Available El objetivo de este trabajo fue determinar los diferentes aspectos cuantitativos y cualitativos que explican la cultura de consumo actual de hortalizas en las familias residentes en la zona sur-sur de Costa Rica. Este trabajo expone resultados relacionados a la caracterización realizada en el 2011 en familias residentes en la denominada zona sur-sur de Costa Rica sobre la cultura de consumo de productos hortícolas. Se aplicaron cuestionarios a una muestra estratificada de familias; lo que permitió establecer la valoración de los precios de mercado, por parte de las familias, para consumir estos alimentos, donde se determinó un valor máximo de US$1,74 millones por semana. Los principales rubros de consumo de acuerdo al valor pagado fueron el tomate, la papa, el plátano, la cebolla y el brócoli, para citar los cinco principales. También fue posible establecer valoraciones cualitativas sobre el consumo de estos productos; por ejemplo se determinó que para el 71,2% de las familias, la frescura representa la característica de mayor valor, además, el principal sitio donde los núcleos familiares realizan las compras de estos alimentos corresponde a supermercados (38,4% de los casos.

  17. Neonatal diabetes and congenital hyperinsulinism caused by mutations in ABCC8/SUR1 are associated with altered and opposite affinities for ATP and ADP

    Directory of Open Access Journals (Sweden)

    Joseph eBryan

    2015-04-01

    Full Text Available ATP-sensitive K+ (KATP channels composed of potassium inward-rectifier type 6.2 and sulfonylurea receptor type 1 subunits (Kir6.2/SUR14 are expressed in various cells in the brain and endocrine pancreas where they couple metabolic status to membrane potential. In β-cells, increases in cytosolic [ATP/ADP]c inhibit KATP channel activity, leading to membrane depolarization and exocytosis of insulin granules. Mutations in ABCC8 (SUR1 or KCNJ11 (Kir6.2 can result in gain or loss of channel activity and cause neonatal diabetes (ND or congenital hyperinsulinism (CHI, respectively. SUR1 is reported to be a Mg2+-dependent ATPase. A prevailing model posits that ATP hydrolysis at SUR1 is required to stimulate openings of the pore. However, recent work shows nucleotide binding, without hydrolysis, is sufficient to switch SUR1 to stimulatory conformations. The actions of nucleotides, ATP and ADP, on ND (SUR1E1506D and CHI (SUR1E1506K mutants, without Kir6.2, were compared to assess both models. Both substitutions significantly impair hydrolysis in SUR1 homologues. SUR1E1506D has greater affinity for MgATP than wildtype; SUR1E1506K has reduced affinity. Without Mg2+, SUR1E1506K has a greater affinity for ATP4- consistent with electrostatic attraction between ATP4-, unshielded by Mg2+, and the basic lysine. Further analysis of ND and CHI ABCC8 mutants in the second transmembrane and nucleotide binding domains (TMD2 & NBD2, found a relation between their affinities for ATP (± Mg2+ and their clinical phenotype. Increased affinity for ATP is associated with ND; decreased affinity with CHI. In contrast, MgADP showed a weaker relationship. Diazoxide, known to reduce insulin release in some CHI cases, potentiates switching of CHI mutants from non-stimulatory to stimulatory states consistent with diazoxide stabilizing a nucleotide-bound conformation. The results emphasize the greater importance of nucleotide binding vs hydrolysis in the regulation of KATP channels

  18. Global contrast based salient region detection

    KAUST Repository

    Cheng, Ming-Ming

    2011-08-25

    Reliable estimation of visual saliency allows appropriate processing of images without prior knowledge of their contents, and thus remains an important step in many computer vision tasks including image segmentation, object recognition, and adaptive compression. We propose a regional contrast based saliency extraction algorithm, which simultaneously evaluates global contrast differences and spatial coherence. The proposed algorithm is simple, efficient, and yields full resolution saliency maps. Our algorithm consistently outperformed existing saliency detection methods, yielding higher precision and better recall rates, when evaluated using one of the largest publicly available data sets. We also demonstrate how the extracted saliency map can be used to create high quality segmentation masks for subsequent image processing.

  19. Global contrast based salient region detection

    KAUST Repository

    Cheng, Ming-Ming; Zhang, Guo-Xin; Mitra, Niloy J.; Huang, Xiaolei; Hu, Shi-Min

    2011-01-01

    Reliable estimation of visual saliency allows appropriate processing of images without prior knowledge of their contents, and thus remains an important step in many computer vision tasks including image segmentation, object recognition, and adaptive compression. We propose a regional contrast based saliency extraction algorithm, which simultaneously evaluates global contrast differences and spatial coherence. The proposed algorithm is simple, efficient, and yields full resolution saliency maps. Our algorithm consistently outperformed existing saliency detection methods, yielding higher precision and better recall rates, when evaluated using one of the largest publicly available data sets. We also demonstrate how the extracted saliency map can be used to create high quality segmentation masks for subsequent image processing.

  20. Macromolecular and dendrimer-based magnetic resonance contrast agents

    Energy Technology Data Exchange (ETDEWEB)

    Bumb, Ambika; Brechbiel, Martin W. (Radiation Oncology Branch, National Cancer Inst., National Inst. of Health, Bethesda, MD (United States)), e-mail: pchoyke@mail.nih.gov; Choyke, Peter (Molecular Imaging Program, National Cancer Inst., National Inst. of Health, Bethesda, MD (United States))

    2010-09-15

    Magnetic resonance imaging (MRI) is a powerful imaging modality that can provide an assessment of function or molecular expression in tandem with anatomic detail. Over the last 20-25 years, a number of gadolinium-based MR contrast agents have been developed to enhance signal by altering proton relaxation properties. This review explores a range of these agents from small molecule chelates, such as Gd-DTPA and Gd-DOTA, to macromolecular structures composed of albumin, polylysine, polysaccharides (dextran, inulin, starch), poly(ethylene glycol), copolymers of cystamine and cystine with GD-DTPA, and various dendritic structures based on polyamidoamine and polylysine (Gadomers). The synthesis, structure, biodistribution, and targeting of dendrimer-based MR contrast agents are also discussed

  1. El (los Sur buscando al Sur. Una construcción entre estereotipos y realidad.

    Directory of Open Access Journals (Sweden)

    Mabel Franzone

    2010-11-01

    Full Text Available Todas las lecturas que podamos hacer del Sur, de sus propias representaciones, de aquellas vehiculizadas por el Norte, de sus creaciones, de sus reacciones, de su búsqueda constante de identidad, son lecturas de múltiples situaciones, que llaman a cruces insoslayables entre pueblos, entre distintas etnias, entre disciplinas, entre sentimientos que van desde el rechazo hasta la atracción casi magnética entre los dos hemisferios. Nuestra intención primera era la de reunir de manera aproximativa las problemáticas actuales de los Sur, ligadas a lo imaginario.

  2. ETUDE DE L’INFLUENCE DES DIFFERENTS PARAMETRES SUR UN MODULE PHOTOVOLTAÏQUE

    Directory of Open Access Journals (Sweden)

    Assia ZERDOUDI

    2015-06-01

    Full Text Available L’Algérie dispose d’environ 3200 heures d’ensoleillement par année, bénéficiant d’une situation climatique favorable à l’application des techniques solaires. La conception des installations efficaces et rentables sur la base des modules solaires est particulièrement importante. Des logiciels dédiés à la simulation des systèmes photovoltaïques peuvent réaliser une vaste et précise analyse, mais ils ne permettent généralement pas à l'utilisateur de modifier les algorithmes. Dans le présent travail, un programme fonctionnant en environnement MATLAB, de la simulation de l'application d'un système photovoltaïque sur la base des modèles mathématiques, de ses composants a été conçu, nous avons modélisé un générateur photovoltaïque en se basant sur les équations électriques et mathématiques qui régissent son comportement ainsi que la dégradation  des caractéristiques de ce générateur en fonction des conditions météorologiques (température et éclairement. Nous avons  réalisé notre étude sur le module SPR 315 E de chez SUNPOWER, qui fournit une puissance de 315 W..

  3. Dendrimer-based Macromolecular MRI Contrast Agents: Characteristics and Application

    Directory of Open Access Journals (Sweden)

    Hisataka Kobayashi

    2003-01-01

    Full Text Available Numerous macromolecular MRI contrast agents prepared employing relatively simple chemistry may be readily available that can provide sufficient enhancement for multiple applications. These agents operate using a ~100-fold lower concentration of gadolinium ions in comparison to the necessary concentration of iodine employed in CT imaging. Herein, we describe some of the general potential directions of macromolecular MRI contrast agents using our recently reported families of dendrimer-based agents as examples. Changes in molecular size altered the route of excretion. Smaller-sized contrast agents less than 60 kDa molecular weight were excreted through the kidney resulting in these agents being potentially suitable as functional renal contrast agents. Hydrophilic and larger-sized contrast agents were found better suited for use as blood pool contrast agents. Hydrophobic variants formed with polypropylenimine diaminobutane dendrimer cores created liver contrast agents. Larger hydrophilic agents are useful for lymphatic imaging. Finally, contrast agents conjugated with either monoclonal antibodies or with avidin are able to function as tumor-specific contrast agents, which also might be employed as therapeutic drugs for either gadolinium neutron capture therapy or in conjunction with radioimmunotherapy.

  4. Sexualidad, migraciones y fronteras en contextos de integración sur-sur

    Directory of Open Access Journals (Sweden)

    Martha Cecilia Ruiz

    Full Text Available Resumen Este artículo se pregunta sobre los procesos de diferenciación, jerarquización e inclusión/exclusión de poblaciones migrantes en contextos migratorios sur-sur, y sobre el rol que juega la sexualidad en estos procesos. Partiendo de un estudio etnográfico sobre las migrantes peruanas y colombianas en el sector del comercio sexual de Ecuador, se analiza la manera en que la sexualidad se convierte en un sitio privilegiado para re-imaginar las diferencias y jerarquías nacionales en un mundo globalizado e integrado regionalmente, y se explica cómo los regímenes de control sobre las migraciones y la sexualidad femenina se articulan entre sí para restablecer el orden idealizado de la nación.

  5. High-contrast MacNeille-PBS-based LCOS projection systems

    Science.gov (United States)

    Chen, Jianmin; Robinson, Michael G.; Sharp, Gary D.

    2005-04-01

    Contrast limits are investigated for MacNeille PBS based LCOS projection systems that use retarder stack filters (RSF). The two contributing factors are considered separately; namely the color management system and the panel port. To enhance performance of the former, skew ray compensated RSFs are introduced. For the latter, a general methodology is presented to optimize contrast by compensating the LCOS panel. It is shown that the orientation of the LCOS panel and compensator, relative to the MacNeille PBS, is critical. The significant impact of AR coating performance on system contrast is also revealed. A high contrast architecture will be presented by way of example.

  6. Effet de la composition de différents substrats culturaux sur ...

    African Journals Online (AJOL)

    SARAH

    31 janv. 2014 ... Effet de la substrats culturaux sur paramètres de croissance ... des graines, mais ce substrat a donné des performances acceptables sur la croissance longitudinale des ..... élevés en conteneurs sur différents types de.

  7. SUR. Breve informe de la Expedición Yelcho al Polo Sur (1909-1910

    Directory of Open Access Journals (Sweden)

    Ursula K. Le Guin

    2013-12-01

    Full Text Available Ursula K. Le Guin Escritora norteamericana, famosa por sus obras de ciencia fi cción y fantasía, en las cuales el tema de género ocupa una posición central. Ganadora de los premios Hugo y Nébula que la catapultaron a la fama. “SUR. A summary report of the Yelcho expedition to the Antarctic, 1909-1910”. Apáreció publicado por primera vez en la revista New Yorker, el 1° de febrero de 1982. La palabra SUR aparece en español en el original. (http://www.newyorker.com/ar Traducción de Susana E. Matallana Peláez

  8. Sur terre comme sur mer: organisations spatiales en mer du Nord et mer de Norvège

    Directory of Open Access Journals (Sweden)

    Maryvonne LE BERRE

    1998-09-01

    Full Text Available L'article montre, au moyen de représentations cartographiques et graphiques, les structures spatiales développées en mer pour l'exploitation des hydrocarbures. Malgré les différences de milieu, l'appropriation et l'occupation territoriales du domaine maritime s'effectuent selon les mêmes principes que sur le continent, à ceci près que ce qui s'étale en surface sur le continent se développe à la verticale en mer.

  9. Regard sur les Lazarets en Terre Canadienne

    Directory of Open Access Journals (Sweden)

    Jean Milot

    2008-01-01

    Full Text Available Puisant dans les nombreuses références qu’offrent les publications médicales canadiennes du milieu du XIXe siècle à nos jours, l’auteur fait découvrir l’existence de lazarets en terre canadienne, décrit l’impact de la maladie sur les conditions vie des lépreux qui y étaient confinés et en souligne les contrecoups tant sur le plan physique et psychologique que social. Il présente un bref aperçu de la maladie, ses symptômes, ses signes ainsi que ses complications oculaires et rappelle les premiers moyens thérapeutiques à base d’huile de chaulmoogra introduits dans la colonie de Tracadie vers 1901. Il illustre son propos en évoquant la vie dans les lazarets de l’île de Sheldrake (1844–1848 et de Tracadie (1848–1965 au Nouveau-Brunswick, puis dans ceux des îles D’Arcy (1891–1924 et de Bentinck (1924–1957 en Colombie-Britannique.

  10. Hausse des taxes sur le tabac et politiques de lutte antitabac au ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Par ailleurs, les études existantes sur les effets des taxes sur le tabac sont fondées sur l'" élasticité de la demande en fonction du prix ", une mesure qui indique l'évolution de la demande globale de cigarettes en réaction à une modification des prix, mais qui ne tient pas compte des effets d'une augmentation des taxes sur ...

  11. Effets des electrons secondaires sur l'ADN

    Science.gov (United States)

    Boudaiffa, Badia

    Les interactions des electrons de basse energie (EBE) representent un element important en sciences des radiations, particulierement, les sequences se produisant immediatement apres l'interaction de la radiation ionisante avec le milieu biologique. Il est bien connu que lorsque ces radiations deposent leur energie dans la cellule, elles produisent un grand nombre d'electrons secondaires (4 x 104/MeV), qui sont crees le long de la trace avec des energies cinetiques initiales bien inferieures a 20 eV. Cependant, il n'y a jamais eu de mesures directes demontrant l'interaction de ces electrons de tres basse energie avec l'ADN, du principalement aux difficultes experimentales imposees par la complexite du milieu biologique. Dans notre laboratoire, les dernieres annees ont ete consacrees a l'etude des phenomenes fondamentaux induits par impact des EBE sur differentes molecules simples (e.g., N2, CO, O2, H2O, NO, C2H 4, C6H6, C2H12) et quelques molecules complexes dans leur phase solide. D'autres travaux effectues recemment sur des bases de l'ADN et des oligonucleotides ont montre que les EBE produisent des bris moleculaires sur les biomolecules. Ces travaux nous ont permis d'elaborer des techniques pour mettre en evidence et comprendre les interactions fondamentales des EBE avec des molecules d'interet biologique, afin d'atteindre notre objectif majeur d'etudier l'effet direct de ces particules sur la molecule d'ADN. Les techniques de sciences des surfaces developpees et utilisees dans les etudes precitees peuvent etre etendues et combinees avec des methodes classiques de biologie pour etudier les dommages de l'ADN induits par l'impact des EBE. Nos experiences ont montre l'efficacite des electrons de 3--20 eV a induire des coupures simple et double brins dans l'ADN. Pour des energies inferieures a 15 eV, ces coupures sont induites par la localisation temporaire d'un electron sur une unite moleculaire de l'ADN, ce qui engendre la formation d'un ion negatif transitoire

  12. Cooperación Sur-Sur: Análisis de su impacto en la transformación del régimen internacional de la OCDE en materia de cooperación internacional

    OpenAIRE

    Londoño Reyes, Alejandra

    2013-01-01

    Las relaciones de cooperación Sur-Sur revoluciona las lógicas tradicionales que dieron base al régimen de la cooperación internacional expedido desde la OCDE. La diferencia entre los donantes llamados “DAC” y los socios “No-DAC” en referencia a los Estados miembros del Comité de Asistencia al Desarrollo establece dos lógicas de cooperación internacional que se contraponen en sus dinámicas pero comparten un objetivo: el desarrollo. Estos dos tipos de relaciones de cooperación se diferencian en...

  13. Contrast Enhancement Algorithm Based on Gap Adjustment for Histogram Equalization

    Science.gov (United States)

    Chiu, Chung-Cheng; Ting, Chih-Chung

    2016-01-01

    Image enhancement methods have been widely used to improve the visual effects of images. Owing to its simplicity and effectiveness histogram equalization (HE) is one of the methods used for enhancing image contrast. However, HE may result in over-enhancement and feature loss problems that lead to unnatural look and loss of details in the processed images. Researchers have proposed various HE-based methods to solve the over-enhancement problem; however, they have largely ignored the feature loss problem. Therefore, a contrast enhancement algorithm based on gap adjustment for histogram equalization (CegaHE) is proposed. It refers to a visual contrast enhancement algorithm based on histogram equalization (VCEA), which generates visually pleasing enhanced images, and improves the enhancement effects of VCEA. CegaHE adjusts the gaps between two gray values based on the adjustment equation, which takes the properties of human visual perception into consideration, to solve the over-enhancement problem. Besides, it also alleviates the feature loss problem and further enhances the textures in the dark regions of the images to improve the quality of the processed images for human visual perception. Experimental results demonstrate that CegaHE is a reliable method for contrast enhancement and that it significantly outperforms VCEA and other methods. PMID:27338412

  14. Contrast Enhancement Algorithm Based on Gap Adjustment for Histogram Equalization

    Directory of Open Access Journals (Sweden)

    Chung-Cheng Chiu

    2016-06-01

    Full Text Available Image enhancement methods have been widely used to improve the visual effects of images. Owing to its simplicity and effectiveness histogram equalization (HE is one of the methods used for enhancing image contrast. However, HE may result in over-enhancement and feature loss problems that lead to unnatural look and loss of details in the processed images. Researchers have proposed various HE-based methods to solve the over-enhancement problem; however, they have largely ignored the feature loss problem. Therefore, a contrast enhancement algorithm based on gap adjustment for histogram equalization (CegaHE is proposed. It refers to a visual contrast enhancement algorithm based on histogram equalization (VCEA, which generates visually pleasing enhanced images, and improves the enhancement effects of VCEA. CegaHE adjusts the gaps between two gray values based on the adjustment equation, which takes the properties of human visual perception into consideration, to solve the over-enhancement problem. Besides, it also alleviates the feature loss problem and further enhances the textures in the dark regions of the images to improve the quality of the processed images for human visual perception. Experimental results demonstrate that CegaHE is a reliable method for contrast enhancement and that it significantly outperforms VCEA and other methods.

  15. Effets de six composts sur les réponses physiologiques ...

    African Journals Online (AJOL)

    Les effets de ces six composts sur le potentiel hydrique, la fuite d'électrolyte, la teneur en amidon des feuilles et sur quelques paramètres agronomiques ont été évalués sur les plantes stressées en comparaison avec les plantes témoins. Les résultats indiquent des valeurs du potentiel hydrique foliaire très faibles et une ...

  16. Sur un deplacement de valeurs: traire et tirer

    Directory of Open Access Journals (Sweden)

    André Burger

    1972-12-01

    Full Text Available L'étymologie de firer est inconnue. Celie que le regretté W. von Wart burg a ern pouvoir avancer est inacceptable: firer serait sorti de marty rier par la grâce d'une fausse coupure mar tirier. Il est plus qu'improbable que cette «étymologie populaire» eût pu se produire si la langue ne possédait pas au préalable un verbe tirier. Au surplus aucun fait n'appuie cette hypothèse. Le FEW, t. VI, 1, p. 396, donne bien pour firer le sens de «torturer sur un treteam>, au XIIIe siècle, et p. 403, «démembrer en faisant tirer les quatre membles par des chevaux» et «torturer (qn en l'étendant sur un tréteau” au XIVe siècle; ces sens sont évidemment trop tardifs pour permettre des conclusions sur l'origine de firer, d'autant plus qu'ils s'expliquent sans peine par la valeur normale du mot, attesté dès la Chanson de Roland, sans aucun rapport avec martirie, mot savant de clerc, qui, dans le même texte s'applique deux fois sur quatre exemples aux Sarrasins, vv. 501 et 1467, où il ne signifie pas «martyre» mais <sur son étymologie et non sur les textes, que tirer aurait à l'origine »einen starken affektiven unterton« (FEW XIII, 2, p. 185. L'étude des exemples de la Chanson de Roland, confrontés avec ceux de traire, nons amènera à une conclusion toute différente.

  17. Effets de l'audit clinique basé sur des critères sur de la qualité de la ...

    African Journals Online (AJOL)

    Effets de l'audit clinique basé sur des critères sur de la qualité de la prise en charge de la prééclampsie sévère dans le Département de Gynécologie Obstétrique du Centre Hospitalier Universitaire Yalgado Ouédraogo, Ouagadougou (Burkina Faso). Sibraogo Kiemtoré, Adama Dembélé, Adama Ouattara, Hyacinthe1,2 ...

  18. Conférence sur l'efficacité

    CERN Document Server

    Jullien, François

    2005-01-01

    Philosophe et sinologue, François Jullien présente ici une conférence qu'il a prononcée auprès de chefs d'entreprise et dans le milieu du management. D'un côté, la conception européenne de l'efficacité est liée à la modélisation comme à la finalité et revendique l'action jusqu'à l'héroïsme ; de l'autre, la pensée chinoise de l'efficience, indirecte et discrète, s'appuie sur le potentiel de situation et induit des " transformations silencieuses ", sans éclat ni même événement. Par-delà cet écart, il s'agira d'interroger la nature de l'effectivité ; ou comment l'intervention humaine réussit à se brancher sur la propension des choses et s'y laisse intégrer. Ce propos se garde donc de séparer tant soit peu l'art d'opérer sur des situations et l'exercice de la philosophie ; en résultent des effets de lecture portant sur l'histoire du XXe siècle ainsi que la géopolitique - et géoéthique - à venir.

  19. Monte Carlo simulation of grating-based neutron phase contrast imaging at CPHS

    International Nuclear Information System (INIS)

    Zhang Ran; Chen Zhiqiang; Huang Zhifeng; Xiao Yongshun; Wang Xuewu; Wie Jie; Loong, C.-K.

    2011-01-01

    Since the launching of the Compact Pulsed Hadron Source (CPHS) project of Tsinghua University in 2009, works have begun on the design and engineering of an imaging/radiography instrument for the neutron source provided by CPHS. The instrument will perform basic tasks such as transmission imaging and computerized tomography. Additionally, we include in the design the utilization of coded-aperture and grating-based phase contrast methodology, as well as the options of prompt gamma-ray analysis and neutron-energy selective imaging. Previously, we had implemented the hardware and data-analysis software for grating-based X-ray phase contrast imaging. Here, we investigate Geant4-based Monte Carlo simulations of neutron refraction phenomena and then model the grating-based neutron phase contrast imaging system according to the classic-optics-based method. The simulated experimental results of the retrieving phase shift gradient information by five-step phase-stepping approach indicate the feasibility of grating-based neutron phase contrast imaging as an option for the cold neutron imaging instrument at the CPHS.

  20. Taxes sur les cigarettes en Tanzanie | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Taxes sur les cigarettes en Tanzanie. De 2002 à 2007, le tabagisme a connu une hausse de 20 % en Tanzanie, une augmentation qui devrait atteindre 46 % en 2016 si la tendance se maintient. On s'attend à ce que cette hausse du tabagisme ait d'importantes répercussions sur la santé publique et le développement ...

  1. Sodium bicarbonate-based hydration prevents contrast-induced nephropathy: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Tamhane Umesh

    2009-05-01

    Full Text Available Abstract Background Contrast-induced nephropathy is the leading cause of in-hospital acute renal failure. This side effect of contrast agents leads to increased morbidity, mortality, and health costs. Ensuring adequate hydration prior to contrast exposure is highly effective at preventing this complication, although the optimal hydration strategy to prevent contrast-induced nephropathy still remains an unresolved issue. Former meta-analyses and several recent studies have shown conflicting results regarding the protective effect of sodium bicarbonate. The objective of this study was to assess the effectiveness of normal saline versus sodium bicarbonate for prevention of contrast-induced nephropathy. Methods The study searched MEDLINE, EMBASE, Cochrane databases, International Pharmaceutical Abstracts database, ISI Web of Science (until 15 December 2008, and conference proceedings for randomized controlled trials that compared normal saline with sodium bicarbonate-based hydration regimen regarding contrast-induced nephropathy. Random-effects models were used to calculate summary odds ratios. Results A total of 17 trials including 2,633 subjects were pooled. Pre-procedural hydration with sodium bicarbonate was associated with a significant decrease in the rate of contrast-induced nephropathy (odds ratios 0.52; 95% confidence interval 0.34–0.80, P = 0.003. Number needed to treat to prevent one case of contrast-induced nephropathy was 16 (95% confidence interval 10–34. No significant differences in the rates of post-procedure hemodialysis (P = 0.20 or death (P = 0.53 was observed. Conclusion Sodium bicarbonate-based hydration was found to be superior to normal saline in prevention of contrast-induced nephropathy in this updated meta-analysis.

  2. Le Projet d’Ole Lando sur les Contrats

    DEFF Research Database (Denmark)

    Holle, Marie-Louise

    2017-01-01

    En 2016 le projet de recherche le plus important jusqu’à présent sur le droit nordique des contrats a pris fin et un livre, de presque 400 pages, en a marqué l’aboutissement. Le résultat du projet est un « restatement » tel qu’il existe aux États-Unis. Le Restatement porte sur les règles et les...

  3. Single particle analysis based on Zernike phase contrast transmission electron microscopy.

    Science.gov (United States)

    Danev, Radostin; Nagayama, Kuniaki

    2008-02-01

    We present the first application of Zernike phase-contrast transmission electron microscopy to single-particle 3D reconstruction of a protein, using GroEL chaperonin as the test specimen. We evaluated the performance of the technique by comparing 3D models derived from Zernike phase contrast imaging, with models from conventional underfocus phase contrast imaging. The same resolution, about 12A, was achieved by both imaging methods. The reconstruction based on Zernike phase contrast data required about 30% fewer particles. The advantages and prospects of each technique are discussed.

  4. Les bases de données pédagogiques sur Internet : le cas du programme Éducasup

    Directory of Open Access Journals (Sweden)

    Christine Develotte

    2005-11-01

    Full Text Available Ces dix dernières années, l'émergence de l'information en ligne a suscité des appels d'offres nationaux visant à la mise en place de bases de données. Nous revenons ici sur l'histoire du programme Éducasup, de sa conception en 1997 à son abandon, fin 2003. À travers une analyse sémio-linguistique des écrans d'accueil de ses différentes chartes graphiques, nous cherchons à montrer les choix politiques et techniques qui ont présidé à l'évolution de ce programme.

  5. Droits, justice et réseaux sociaux sur Internet (Amérique latine ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... sur la question de la protection des renseignements personnels sur Internet, ... Derechos y justicia y el movimiento social en internet (5 de agosto de 2009 ... Programme de recherche sur le virus Zika Canada-Amérique latine et Caraïbes.

  6. Utility decay rates of T1-weighted magnetic resonance imaging contrast based on redox-sensitive paramagnetic nitroxyl contrast agents

    International Nuclear Information System (INIS)

    Matsumoto, Ken-ichiro

    2009-01-01

    The availability and applicability of the combination of paramagnetic nitroxyl contrast agent and T 1 -weighted gradient echo (GE)-based dynamic magnetic resonance imaging (MRI) measurement for redox imaging are described. The time courses of T 1 -weighted GE MRI signal intensities according to first-order paramagnetic loss of a nitroxyl contrast agent were simulated for several experimental conditions. The apparent decay rate calculated based on decreasing T 1 -weighted MRI contrast (k MRI ) can show an approximate value of the original decay rate (k true ) discretionarily given for simulation with suitable experimental parameters. The difference between k MRI and k true can be sufficiently small under T 1 -weighted spoiled gradient echo (SPGR) scan conditions (repetition time=75 ms, echo time=3 ms, and flip angle=45deg), with a conventional redox-sensitive nitroxyl contrast agent, such as 4-hydroxy-2,2,6,6,-tetramethylpiperidine-N-oxyl (TEMPOL) and/or 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl (carbamoyl-PROXYL), and with intravenous (i.v.) doses of below 1.5 γmol/g body weight (b.w.) for mice. The results of this simulation suggest that the k MRI of nitroxyl contrast agents can be the primary index of redox status under biological conditions. (author)

  7. Contrast enhancement technique in brain 3D-CTA studies. Optimizing the amount of contrast medium according to scan time based on TDC

    International Nuclear Information System (INIS)

    Terasawa, Kazuaki; Hatcho, Atsushi

    2008-01-01

    In three-dimensional CT angiography (3D-CTA), good reproducibility can be obtained by maintaining the maximum CT numbers (HU) at a specified level. However, the correlation between the scan time and the injection time showed that the maximum CT numbers increased and varied due to the additional contrast enhancement effect from recirculation of the injected contrast medium for longer injection times when the dose of iodinated contrast medium per unit time (mgI/s) was maintained at a specified level based on the time-density curve (TDC) of the phantom. The amount of contrast medium employed at our hospital has been optimized based on an iodinated contrast medium dose per unit time providing a contrast enhancement effect of 300 HU in the middle cerebral artery. Using this standard, a TDC phantom was employed to obtain an iodinated contrast medium dose per unit time, permitting equivalent maximum CT values (used as standard values) to be obtained by changing the injection time. A contrast-enhancement technique that accounts for the variation in the scan time was evaluated. Strong correlations were observed between the scan time and the injection time (R 2 =0.969) and between the injection time and the dose of iodinated contrast medium per unit body weight (R 2 =0.994). We conclude that adjusting the dose of iodinated contrast medium per unit body weight per unit time according to the scan time permits optimization of the contrast-enhancement technique. (author)

  8. Erbium-Based Perfusion Contrast Agent for Small-Animal Microvessel Imaging

    Directory of Open Access Journals (Sweden)

    Justin J. Tse

    2017-01-01

    Full Text Available Micro-computed tomography (micro-CT facilitates the visualization and quantification of contrast-enhanced microvessels within intact tissue specimens, but conventional preclinical vascular contrast agents may be inadequate near dense tissue (such as bone. Typical lead-based contrast agents do not exhibit optimal X-ray absorption properties when used with X-ray tube potentials below 90 kilo-electron volts (keV. We have developed a high-atomic number lanthanide (erbium contrast agent, with a K-edge at 57.5 keV. This approach optimizes X-ray absorption in the output spectral band of conventional microfocal spot X-ray tubes. Erbium oxide nanoparticles (nominal diameter 4000 Hounsfield units, and perfusion of vessels < 10 μm in diameter was demonstrated in kidney glomeruli. The described new contrast agent facilitated the visualization and quantification of vessel density and microarchitecture, even adjacent to dense bone. Erbium’s K-edge makes this contrast agent ideally suited for both single- and dual-energy micro-CT, expanding potential preclinical research applications in models of musculoskeletal, oncological, cardiovascular, and neurovascular diseases.

  9. Quantitative breast tissue characterization using grating-based x-ray phase-contrast imaging

    Science.gov (United States)

    Willner, M.; Herzen, J.; Grandl, S.; Auweter, S.; Mayr, D.; Hipp, A.; Chabior, M.; Sarapata, A.; Achterhold, K.; Zanette, I.; Weitkamp, T.; Sztrókay, A.; Hellerhoff, K.; Reiser, M.; Pfeiffer, F.

    2014-04-01

    X-ray phase-contrast imaging has received growing interest in recent years due to its high capability in visualizing soft tissue. Breast imaging became the focus of particular attention as it is considered the most promising candidate for a first clinical application of this contrast modality. In this study, we investigate quantitative breast tissue characterization using grating-based phase-contrast computed tomography (CT) at conventional polychromatic x-ray sources. Different breast specimens have been scanned at a laboratory phase-contrast imaging setup and were correlated to histopathology. Ascertained tumor types include phylloides tumor, fibroadenoma and infiltrating lobular carcinoma. Identified tissue types comprising adipose, fibroglandular and tumor tissue have been analyzed in terms of phase-contrast Hounsfield units and are compared to high-quality, high-resolution data obtained with monochromatic synchrotron radiation, as well as calculated values based on tabulated tissue properties. The results give a good impression of the method’s prospects and limitations for potential tumor detection and the associated demands on such a phase-contrast breast CT system. Furthermore, the evaluated quantitative tissue values serve as a reference for simulations and the design of dedicated phantoms for phase-contrast mammography.

  10. Recherche en partenariat sur la transition nutritionnelle et les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    l'évolution du risque a suivi et a débouché sur une stratégie de prévention ... de recherche ont pu avoir un impact sur les politiques et pro- .... Deux études étaient donc entreprises ..... à la même thématique et de recruter par eux-mêmes les.

  11. Renforcement de l'influence de la recherche sur l'élaboration des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Réflexions

    influent sur les politiques, mais de façons différentes. Le lien entre recherche et influence sur les politiques n'est ... Renforcement de l'influence de la recherche sur l'élaboration des politiques d'adaptation. PA. NOS. /G .... ceux de la CMAE ont dit avoir besoin de soutien technique. Il était malheureusement difficile pour le ...

  12. Nephrogenic systemic fibrosis (NSF) and gadolinium-based contrast ...

    African Journals Online (AJOL)

    Nephrogenic systemic fibrosis (NSF), unknown before March 1997 and first described in 2000, is a systemic disorder characterised by widespread tissue fibrosis. The first known case occurred in 1997, after the use of gadolinium-based contrast agents (GBCAs) at high doses in patients with renal failure had become routine.

  13. Investigation of the imaging quality of synchrotron-based phase-contrast mammographic tomography

    International Nuclear Information System (INIS)

    Gureyev, T E; Mayo, S C; Nesterets, Ya I; Mohammadi, S; Menk, R H; Arfelli, F; Tromba, G; Lockie, D; Pavlov, K M; Kitchen, M J; Zanconati, F; Dullin, C

    2014-01-01

    We report the results of a systematic study of phase-contrast x-ray computed tomography in the propagation-based and analyser-based modes using specially designed phantoms and excised breast tissue samples. The study is aimed at the quantitative evaluation and subsequent optimization, with respect to detection of small tumours in breast tissue, of the effects of phase contrast and phase retrieval on key imaging parameters, such as spatial resolution, contrast-to-noise ratio, x-ray dose and a recently proposed ‘intrinsic quality’ characteristic which combines the image noise with the spatial resolution. We demonstrate that some of the methods evaluated in this work lead to substantial (more than 20-fold) improvement in the contrast-to-noise and intrinsic quality of the reconstructed tomographic images compared with conventional techniques, with the measured characteristics being in good agreement with the corresponding theoretical estimations. This improvement also corresponds to an approximately 400-fold reduction in the x-ray dose, compared with conventional absorption-based tomography, without a loss in the imaging quality. The results of this study confirm and quantify the significant potential benefits achievable in three-dimensional mammography using x-ray phase-contrast imaging and phase-retrieval techniques. (paper)

  14. Hafnium-Based Contrast Agents for X-ray Computed Tomography.

    Science.gov (United States)

    Berger, Markus; Bauser, Marcus; Frenzel, Thomas; Hilger, Christoph Stephan; Jost, Gregor; Lauria, Silvia; Morgenstern, Bernd; Neis, Christian; Pietsch, Hubertus; Sülzle, Detlev; Hegetschweiler, Kaspar

    2017-05-15

    Heavy-metal-based contrast agents (CAs) offer enhanced X-ray absorption for X-ray computed tomography (CT) compared to the currently used iodinated CAs. We report the discovery of new lanthanide and hafnium azainositol complexes and their optimization with respect to high water solubility and stability. Our efforts culminated in the synthesis of BAY-576, an uncharged hafnium complex with 3:2 stoichiometry and broken complex symmetry. The superior properties of this asymmetrically substituted hafnium CA were demonstrated by a CT angiography study in rabbits that revealed excellent signal contrast enhancement.

  15. Espacio herido, tiempo acelerado, imaginario conmovido. Interrogantes sobre la postmodernidad del Sur.

    Directory of Open Access Journals (Sweden)

    Mabel Franzone

    2010-11-01

    Full Text Available Estableciendo una relación estrecha entre espacio, tiempo e imaginario, este escrito intenta tratar la gran separación Norte- Sur, acaecida con la hipermodernidad y sus consecuencias sobre la destrucción del espacio del Sur ; la cuestión de fondo encara las huellas que puede dejar en los cuerpos y en los imaginarios. Los límites impuestos se tratan en cuatro niveles : históricos, geográficos, económicos- sociales y de la representación. Para una crítica de la modernidad se han tomado parámetros de pensamiento que operan en una trama mediana, forma de pensar propia al Sur y que muestran la necesidad de una epistemología también propia al Sur, que refleje las cuestiones fundamentales y que tenga en cuenta la emancipación y la solidaridad como categorías para repensar el Sur.

  16. Estilos estructurales del Subandino Sur de Bolivia

    OpenAIRE

    Rocha, Emilio

    2013-01-01

    El Subandino Sur de Bolivia es una típica faja plegada y corrida de lámina delgada, con una notable regularidad en la geometría de las estructuras. Esta es una característica típica de las fajas plegadas en las que no se involucra el basamento en la deformación. Sin embargo, cuando se analiza en detalle la geometría y evolución de la deformación del Subandino Sur, se verifica que existen numerosas desviaciones de dicha regularidad. En el presente trabajo se estudiaron los diferentes procesos ...

  17. Le lancement canadien du Rapport sur les politiques alimentaires ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 mai 2018 ... Cet événement sera filmé, puis accessible en ligne sur la chaîne YouTube du CRDI. Le Rapport sur les politiques alimentaires mondiales 2018 passe en revue les principaux faits nouveaux et événements en matière de politiques alimentaires survenus au cours de l'année. D'éminents chercheurs ...

  18. Analyse technico–économique des Aliments densifies sur les ...

    African Journals Online (AJOL)

    Une étude portant sur l'influence des aliments densifiés sur la performance de croissance des boucs roux de Maradi a été conduite entre juillet 2016 à septembre 2016. Quarante deux (42) boucs ont été répartis au hasard en six lots de sept individus. Chaque lot correspond à un aliment ou traitement préparé à partir des.

  19. FUZZY BASED CONTRAST STRETCHING FOR MEDICAL IMAGE ENHANCEMENT

    Directory of Open Access Journals (Sweden)

    T.C. Raja Kumar

    2011-07-01

    Full Text Available Contrast Stretching is an important part in medical image processing applications. Contrast is the difference between two adjacent pixels. Fuzzy statistical values are analyzed and better results are produced in the spatial domain of the input image. The histogram mapping produces the resultant image with less impulsive noise and smooth nature. The probabilities of gray values are generated and the fuzzy set is determined from the position of the input image pixel. The result indicates the good performance of the proposed fuzzy based stretching. The inverse transform of the real values are mapped with the input image to generate the fuzzy statistics. This approach gives a flexible image enhancement for medical images in the presence of noises.

  20. Concilier plaisir et nutrition. Travaux des groupes de travail PNNS sur les lipides et sur le goût

    OpenAIRE

    Souliac , L.; Bizet, G.; Remy, S.

    2010-01-01

    Les ministères chargés de l'alimentation et de la santé ont incité les opérateurs à mettre sur le marché des aliments moins riches en lipides, par la signature avec l'État de chartes d'engagement sur la composition nutritionnelle. L'observatoire de la qualité de l'alimentation suit l'évolution de ces efforts. Les lipides ont un rôle technologique et sensoriel important qu'il convient de prendre en considération. Il est aujourd'hui possible d'améliorer le profil nutritionnel des aliments, tout...

  1. Données préliminaires sur le paludisme humain en zones rurale et ...

    African Journals Online (AJOL)

    SARAH

    31 juil. 2017 ... axée sur le diagnostic précoce et la prise en charge rapide des ... recherche investigue sur les connaissances, attitudes et ... paludisme et (vi) sur la source de traitement du paludisme. ... technique ELISA (Burkot et al., 1984).

  2. Enquêtes sur les soucoupes volantes

    OpenAIRE

    Lagrange, Pierre

    2007-01-01

    La dispute autour du mot « preuve » se réduit à une question : Qu'est-ce qui constitue une preuve ? Faut-il qu'un ovni atterrisse à l'entrée du Pentagone, près des bureaux des chefs d'État-Major ? Ou bien est-ce une preuve quand une station de radar au sol détecte un ovni, envoie un jet l'intercepter, que le pilote du jet le voit et le suit sur son radar pour finir par le voir disparaître à une vitesse phénoménale ? Ou est-ce une preuve quand un pilote tire sur un ovni et maintient son histoi...

  3. Characterization of nanoparticle-based contrast agents for molecular magnetic resonance imaging

    International Nuclear Information System (INIS)

    Shan, Liang; Chopra, Arvind; Leung, Kam; Eckelman, William C.; Menkens, Anne E.

    2012-01-01

    The development of molecular imaging agents is currently undergoing a dramatic expansion. As of October 2011, ∼4,800 newly developed agents have been synthesized and characterized in vitro and in animal models of human disease. Despite this rapid progress, the transfer of these agents to clinical practice is rather slow. To address this issue, the National Institutes of Health launched the Molecular Imaging and Contrast Agents Database (MICAD) in 2005 to provide freely accessible online information regarding molecular imaging probes and contrast agents for the imaging community. While compiling information regarding imaging agents published in peer-reviewed journals, the MICAD editors have observed that some important information regarding the characterization of a contrast agent is not consistently reported. This makes it difficult for investigators to evaluate and meta-analyze data generated from different studies of imaging agents, especially for the agents based on nanoparticles. This article is intended to serve as a guideline for new investigators for the characterization of preclinical studies performed with nanoparticle-based MRI contrast agents. The common characterization parameters are summarized into seven categories: contrast agent designation, physicochemical properties, magnetic properties, in vitro studies, animal studies, MRI studies, and toxicity. Although no single set of parameters is suitable to define the properties of the various types of contrast agents, it is essential to ensure that these agents meet certain quality control parameters at the preclinical stage, so that they can be used without delay for clinical studies.

  4. Réseau ibéro-américain d'analyse de données sur la criminalité et ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Grâce à ce projet, le Red Iberoamericana de Análisis de Datos de la Delincuencia (RIADD) sera en mesure de recueillir et d'analyser des données sur la criminalité et la sécurité dans 14 pays d'Amérique latine. Les résultats permettront de constituer une base de données statistiques exhaustive et fiable sur la criminalité, ...

  5. Hausse des taxes sur le tabac dans trois pays d'Amérique centrale ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les chercheurs mèneront des études sur la demande de produits du tabac dans le ... sur les techniques modernes de contrôle de la chaîne d'approvisionnement, ... IWRA/CRDI sur les changements climatiques et la gestion adaptive de l'eau.

  6. Contrast-enhanced voiding urosonography phantom study: intravenous iodinated and gadolinium-based contrast agents may cause false-negative results in assessment of vesicoureteral reflux in children

    International Nuclear Information System (INIS)

    Veldhoen, Simon; Sauer, Alexander; Gassenmaier, Tobias; Petritsch, Bernhard; Herz, Stefan; Blanke, Philipp; Bley, Thorsten A.; Wirth, Clemens; Derlin, Thorsten

    2015-01-01

    Contrast-enhanced voiding urosonography (ce-VUS) is commonly requested simultaneously to other diagnostic imaging necessitating intravenous contrast agents. To date there is limited knowldedge about intravesical interactions between different types of contrast agents. To assess the effect of excreted intravenous iodinated and gadolinium-based contrast agents on the intravesical distribution of ultrasound contrast within contrast-enhanced voiding urosonography. Iodinated (iomeprol, iopamidol) and gadolinium-based (gadoterate meglumine) contrast agents were diluted to bladder concentration and injected into balloons filled with saline solution. CT scans were performed to assess the contrast distribution in these phantoms. Regions of interest were placed at the top and bottom side of each balloon and Hounsfield units (HU) were measured. Three other balloons were filled with saline solution and contrast media likewise. The ultrasound contrast agent sulphur hexafluoride was added and its distribution was assessed using sonography. MDCT scans showed a separation of two liquid layers in all bladder phantoms with the contrast layers located at the bottom and the saline solution at the top. Significant differences of the HU measurements at the top and bottom side were observed (P < 0.001-0.007). Following injection of ultrasound contrast agent, US showed its distribution exclusively among the saline solution. False-negative results of contrast-enhanced voiding urosonography may occur if it is performed shortly after imaging procedures requiring intravenous contrast. (orig.)

  7. Une nouvelle ouverture sur le monde pour les femmes | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    'appellent ailleurs dans le dédale d'étals et d'allées serrés. En plus de son travail sur le marché, Jertrudes est également secrétaire de l'association des femmes qui vendent sur ce marché. Le groupe est un endroit où elles ...

  8. A case report on a severe anaphylaxis reaction to Gadolinium-based MR contrast media

    Energy Technology Data Exchange (ETDEWEB)

    Park, Juil; Kim, Tae Hyung; Park, Chang Min; Yoon, Soon Ho; Lee, Whal; Kang, Hye Ryun; Choi, Young Hun [Seoul National University Hospital, Seoul (Korea, Republic of)

    2017-02-15

    Acute hypersensitivity reactions to gadolinium-based magnetic resonance (MR) contrast media have been shown to have a much lower incidence and they are generally milder in terms of severity than acute adverse reactions associated with the use of iodinated contrast media for computed tomography scans. However, even though it is rare, a severe hypersensitivity reaction to MR contrast media can occur. Here we present the case of a 66-year-old woman who experienced a severe hypersensitivity reaction after administration of gadolinium-based contrast media without a previous history of allergies.

  9. Influence de l'irrigation sur le rendement et sur la qualité des raisins

    Directory of Open Access Journals (Sweden)

    J. Cerny

    1968-12-01

     Le travail présenté résume les résultats de l'expérience avec l'irrigation supplémentaire de la vigne dans le domaine sec du Sud de la Moravie ainsi que son influence sur le rendement et la qualité des raisins.

  10. Analyzer-based x-ray phase-contrast microscopy combining channel-cut and asymmetrically cut crystals

    International Nuclear Information System (INIS)

    Hoennicke, M. G.; Cusatis, C.

    2007-01-01

    An analyzer-based x-ray phase-contrast microscopy (ABM) setup combining a standard analyzer-based x-ray phase-contrast imaging (ABI) setup [nondispersive 4-crystal setup (Bonse-Hart setup)] and diffraction by asymmetrically cut crystals is presented here. An attenuation-contrast microscopy setup with conventional x-ray source and asymmetrically cut crystals is first analyzed. Edge-enhanced effects attributed to phase jumps or refraction/total external reflection on the fiber borders were detected. However, the long exposure times and the possibility to achieve high contrast microscopies by using extremely low attenuation-contrast samples motivated us to assemble the ABM setup using a synchrotron source. This setup was found to be useful for low contrast attenuation samples due to the low exposure time, high contrast, and spatial resolution found. Moreover, thanks to the combination with the nondispersive ABI setup, the diffraction-enhanced x-ray imaging algorithm could be applied

  11. Impact des traitements physicochimiques sur la clarte des hydrogels ...

    African Journals Online (AJOL)

    Méthodes : La préparation est réalisée selon la méthode décrite par PINGNAULT utilisant 4% (P/P) d'amidon en base sèche.Sur les gels obtenu ont été déterminés successivement l'influence de la conservation au froid (4°C) par la méthode de CRAIG, de la longueur d'onde entre 400 et 700 nm, de la concentration en ...

  12. Use of small reactors as an alternative to supply electricity to Baja California Sur; Uso de reactores pequenos como alternativa de suministro de electricidad para Baja California Sur

    Energy Technology Data Exchange (ETDEWEB)

    Alonso, G.; Portes, E.; Ramirez, J. R. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Ortega, G., E-mail: gustavo.alonso@inin.gob.mx [Comision Federal de Electricidad, Rio Rodano No. 14, 06500 Ciudad de Mexico (Mexico)

    2016-09-15

    The state of Baja California Sur (Mexico) does not form part of the national interconnected electrical system of the country, reason why is local its electrical power supply; one of the alternatives to cover future demands is the use of gas-based combined cycles, which presents the additional problem of including a high price for gas transportation in its costs. In order to reduce total costs, including investment, fuels and operation and maintenance in the operation of the Baja California Sur state electricity system in the coming years, mainly due to the estimated natural gas cost order of $11.50 dollars per million BTU, a proposal is presented to reduce the costs of the electrical system by replacing the necessary combined cycles with the new Small Modular Reactor type nuclear reactors, this alternative is economically competitive. (Author)

  13. Analyse pragma-énonciative des s/citations du site d’Arrêt sur images A pragma-enunciative analysis of quotations on the Web site Arrêt sur images (Freeze-frame

    Directory of Open Access Journals (Sweden)

    Alain Rabatel

    2010-04-01

    Full Text Available Cet article analyse différentes formes de citations dans les sites de presse sur le WEB, en prenant comme exemple le site d’Arrêt sur images. Après avoir analysé les deux grandes catégories d’enchâssements énonciatifs à l’œuvre sur le site et dégagé quelques spécificités du discours représenté/montré et du discours d’escorte qui commente le précédent, l’article montre que le discours d’escorte joue un rôle argumentatif majeur dans la mesure où il fait plus qu’inciter le lecteur à faire apparaître les citations, il les présente comme des éléments de preuve, bref, comme des citations à faire comparaître. La fonction rhétorico-argumentative de ces citations est confirmée par le procédé du montage, qui démonte les situations servant de support à une démonstration basée sur des preuves. Enfin, compte tenu du caractère médiacritique du site, le discours d’escorte construit un ethos de professionnalisme exigeant et une communauté discursive et interprétative soudée autour de valeurs partagées.This article analyzes different forms of quotation on Web press sites, using the site Arrêt sur images as an example. After analyzing the two large categories of enunciative embeddings at work on the site and identifying the marks of direct represented/shown discourse and accompanying discourse, it shows that accompanying discourse plays a major argumentative role in so far as it does more than incite the reader to display the quotations, it presents them as elements of proof, in short, as quotations to be summoned. The rhetoric-argumentative function of quotations is confirmed through the process of editing, which dissects the situation while serving as a support to demonstration. This editing rests on a circular logic of justification based on proof. At last, considering the media critical character of the site, the accompanying discourse constructs an ethos of demanding professionalism and a united

  14. Chaire de recherche trilatérale Canada – Afrique du Sud sur les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le présent projet met l'accent sur les interactions entre l'humain et la faune, notamment sur les pauvres des zones rurales en pays tropical et sur l'effet des changements climatiques que ces derniers subiront. Puisant dans la recherche menée à la station de biologie expérimentale de l'Université Makere, près du parc ...

  15. Rapport annuel au Parlement Loi sur la protection des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Larocque, Samia

    1 juil. 1983 ... TBS/SCT 350-63 (Rév. 2011/03). 31/03/2014. 01/04/2013. Période visée par le rapport : Reçues pendant la période visée par le rapport. Total. En suspens à la fin de la période de rapport précédente. Rapport statistique sur la Loi sur la protection des renseignements personnels. Nom de l'institution :.

  16. Recent advances in synchrotron-based hard x-ray phase contrast imaging

    International Nuclear Information System (INIS)

    Liu, Y; Nelson, J; Andrews, J C; Pianetta, P; Holzner, C

    2013-01-01

    Ever since the first demonstration of phase contrast imaging (PCI) in the 1930s by Frits Zernike, people have realized the significant advantage of phase contrast over conventional absorption-based imaging in terms of sensitivity to ‘transparent’ features within specimens. Thus, x-ray phase contrast imaging (XPCI) holds great potential in studies of soft biological tissues, typically containing low Z elements such as C, H, O and N. Particularly when synchrotron hard x-rays are employed, the favourable brightness, energy tunability, monochromatic characteristics and penetration depth have dramatically enhanced the quality and variety of XPCI methods, which permit detection of the phase shift associated with 3D geometry of relatively large samples in a non-destructive manner. In this paper, we review recent advances in several synchrotron-based hard x-ray XPCI methods. Challenges and key factors in methodological development are discussed, and biological and medical applications are presented. (paper)

  17. Recent advances in synchrotron-based hard x-ray phase contrast imaging

    Science.gov (United States)

    Liu, Y.; Nelson, J.; Holzner, C.; Andrews, J. C.; Pianetta, P.

    2013-12-01

    Ever since the first demonstration of phase contrast imaging (PCI) in the 1930s by Frits Zernike, people have realized the significant advantage of phase contrast over conventional absorption-based imaging in terms of sensitivity to ‘transparent’ features within specimens. Thus, x-ray phase contrast imaging (XPCI) holds great potential in studies of soft biological tissues, typically containing low Z elements such as C, H, O and N. Particularly when synchrotron hard x-rays are employed, the favourable brightness, energy tunability, monochromatic characteristics and penetration depth have dramatically enhanced the quality and variety of XPCI methods, which permit detection of the phase shift associated with 3D geometry of relatively large samples in a non-destructive manner. In this paper, we review recent advances in several synchrotron-based hard x-ray XPCI methods. Challenges and key factors in methodological development are discussed, and biological and medical applications are presented.

  18. Des pratiques culturales influent sur les attaques de deux ravageurs ...

    African Journals Online (AJOL)

    La culture de tomate est attaquée par plusieurs ravageurs dont Helicoverpa armigera et Tuta absoluta. Dans le but d'évaluer l'effet des pratiques culturales de la tomate sur ces principaux ravageurs dans les Niayes (Sénégal), un échantillonnage de 98 parcelles est effectué, sur quatre cycles de culture en saison sèche, de ...

  19. SurR9C84A protects and recovers human cardiomyocytes from hypoxia induced apoptosis

    Energy Technology Data Exchange (ETDEWEB)

    Ashok, Ajay [Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Faculty of Health, Centre for Molecular and Medical Research - C-MMR, Deakin University, Waurn Ponds, Victoria 3216 (Australia); Department of Pathology, Case Western Reserve University, 2103 Cornell Rd. WRB 5128, Cleveland, OH 44106-7288 (United States); Kanwar, Jagat Rakesh [Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Faculty of Health, Centre for Molecular and Medical Research - C-MMR, Deakin University, Waurn Ponds, Victoria 3216 (Australia); Krishnan, Uma Maheswari [Centre for Nanotechnology & Advanced Biomaterials (CeNTAB), School of Chemical & Biotechnology (SCBT), SASTRA University, Thanjavur 613401 (India); Kanwar, Rupinder Kaur, E-mail: rupinder.kanwar@deakin.edu.au [Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Faculty of Health, Centre for Molecular and Medical Research - C-MMR, Deakin University, Waurn Ponds, Victoria 3216 (Australia)

    2017-01-01

    Survivin, as an anti-apoptotic protein and a cell cycle regulator, is recently gaining importance for its regenerative potential in salvaging injured hypoxic cells of vital organs such as heart. Different strategies are being employed to upregulate survivin expression in dying hypoxic cardiomyocytes. We investigated the cardioprotective potential of a cell permeable survivin mutant protein SurR9C84A, for the management of hypoxia mediated cardiomyocyte apoptosis, in a novel and clinically relevant model employing primary human cardiomyocytes (HCM). The aim of this research work was to study the efficacy and mechanism of SurR9C84A facilitated cardioprotection and regeneration in hypoxic HCM. To mimic hypoxic microenvironment in vitro, well characterized HCM were treated with 100 µm (48 h) cobalt chloride to induce hypoxia. Hypoxia induced (HI) HCM were further treated with SurR9C84A (1 µg/mL) in order to analyse its cardioprotective efficacy. Confocal microscopy showed rapid internalization of SurR9C84A and scanning electron microscopy revealed the reinstatement of cytoskeleton projections in HI HCM. SurR9C84A treatment increased cell viability, reduced cell death via, apoptosis (Annexin-V assay), and downregulated free cardiac troponin T and MMP-9 expression. SurR9C84A also upregulated the expression of proliferation markers (PCNA and Ki-67) and downregulated mitochondrial depolarization and ROS levels thereby, impeding cell death. Human Apoptosis Array further revealed that SurR9C84A downregulated expression of pro-apoptotic markers and augmented expression of HSPs and HTRA2/Omi. SurR9C84A treatment led to enhanced levels of survivin, VEGF, PI3K and pAkt. SurR9C84A proved non-toxic to normoxic HCM, as validated through unaltered cell proliferation and other marker levels. Its pre-treatment exhibited lesser susceptibility to hypoxia/damage. SurR9C84A holds a promising clinical potential for human cardiomyocyte survival and proliferation following hypoxic injury

  20. Les mesures de gel et de confiscation en vertu de la Loi sur les embargos

    OpenAIRE

    Schnyder, Nicolas

    2009-01-01

    Etude du mécanisme d'adoption des mesures de gel et de confiscation en vertu de la Loi sur les embargos et leurs conséquences tant sur la personne principalement touchée par ces mesures que sur les tiers.

  1. Commission des Nations Unies sur les produits indispensables aux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude des soins de santé primaires dispensés dans les pays du cône Sud. Les pays membres du Réseau de recherche sur les systèmes et services de santé dans les pays du cône Sud (Red de Investigación en Sistemas y Servicios de Salud en el Cono Sur) ont des systèmes de... Voir davantageÉtude des soins de santé ...

  2. Fast mutual-information-based contrast enhancement

    Science.gov (United States)

    Cao, Gang; Yu, Lifang; Tian, Huawei; Huang, Xianglin; Wang, Yongbin

    2017-07-01

    Recently, T. Celik proposed an effective image contrast enhancement (CE) method based on spatial mutual information and PageRank (SMIRANK). According to the state-of-the-art evaluation criteria, it achieves the best visual enhancement quality among existing global CE methods. However, SMIRANK runs much slower than the other counterparts, such as histogram equalization (HE) and adaptive gamma correction. Low computational complexity is also required for good CE algorithms. In this paper, we novelly propose a fast SMIRANK algorithm, called FastSMIRANK. It integrates both spatial and gray-level downsampling into the generation of pixel value mapping function. Moreover, the computation of rank vectors is speeded up by replacing PageRank with a simple yet efficient row-based operation of mutual information matrix. Extensive experimental results show that the proposed FastSMIRANK could accelerate the processing speed of SMIRANK by about 20 times, and is even faster than HE. Comparable enhancement quality is preserved simultaneously.

  3. Fuzzy Logic-Based Histogram Equalization for Image Contrast Enhancement

    Directory of Open Access Journals (Sweden)

    V. Magudeeswaran

    2013-01-01

    Full Text Available Fuzzy logic-based histogram equalization (FHE is proposed for image contrast enhancement. The FHE consists of two stages. First, fuzzy histogram is computed based on fuzzy set theory to handle the inexactness of gray level values in a better way compared to classical crisp histograms. In the second stage, the fuzzy histogram is divided into two subhistograms based on the median value of the original image and then equalizes them independently to preserve image brightness. The qualitative and quantitative analyses of proposed FHE algorithm are evaluated using two well-known parameters like average information contents (AIC and natural image quality evaluator (NIQE index for various images. From the qualitative and quantitative measures, it is interesting to see that this proposed method provides optimum results by giving better contrast enhancement and preserving the local information of the original image. Experimental result shows that the proposed method can effectively and significantly eliminate washed-out appearance and adverse artifacts induced by several existing methods. The proposed method has been tested using several images and gives better visual quality as compared to the conventional methods.

  4. Estimasi Model Seemingly Unrelated Regression (SUR dengan Metode Generalized Least Square (GLS

    Directory of Open Access Journals (Sweden)

    Ade Widyaningsih

    2015-04-01

    Full Text Available Regression analysis is a statistical tool that is used to determine the relationship between two or more quantitative variables so that one variable can be predicted from the other variables. A method that can used to obtain a good estimation in the regression analysis is ordinary least squares method. The least squares method is used to estimate the parameters of one or more regression but relationships among the errors in the response of other estimators are not allowed. One way to overcome this problem is Seemingly Unrelated Regression model (SUR in which parameters are estimated using Generalized Least Square (GLS. In this study, the author applies SUR model using GLS method on world gasoline demand data. The author obtains that SUR using GLS is better than OLS because SUR produce smaller errors than the OLS.

  5. Estimasi Model Seemingly Unrelated Regression (SUR dengan Metode Generalized Least Square (GLS

    Directory of Open Access Journals (Sweden)

    Ade Widyaningsih

    2014-06-01

    Full Text Available Regression analysis is a statistical tool that is used to determine the relationship between two or more quantitative variables so that one variable can be predicted from the other variables. A method that can used to obtain a good estimation in the regression analysis is ordinary least squares method. The least squares method is used to estimate the parameters of one or more regression but relationships among the errors in the response of other estimators are not allowed. One way to overcome this problem is Seemingly Unrelated Regression model (SUR in which parameters are estimated using Generalized Least Square (GLS. In this study, the author applies SUR model using GLS method on world gasoline demand data. The author obtains that SUR using GLS is better than OLS because SUR produce smaller errors than the OLS.

  6. Parametric based morphological transformation for contrast ...

    Indian Academy of Sciences (India)

    for contrast enhancement of color images in poor-lighting ... high and low mean brightness value, there is a significant change in the view of the enhanced ... The two most fundamental morphological operations dilation and erosion are defined by ..... Menotti David 2007 Multi-histogram equalization methods for contrast ...

  7. Effets de l'alimentation des poissons avec Azolla sur la production d'un écosystème agro-piscicole en zones marécageuses au Rwanda

    Directory of Open Access Journals (Sweden)

    Kanangire, CK.

    2002-01-01

    Full Text Available Effects of Azolla-based Meal on the Production of an Agro-piscicultural Ecosystem in Rwanda Marshlands. Cette étude analyse les différences de caractères au niveau de la descendance des croisements interspécifiques entre Sesamum indicum L. et Ceratotheca sesamoides Endl. Les résultats obtenus montrent que l'héritabilité de la présence d'une forte pilosité sur les tiges et sur les pétioles est contrôlée par deux gènes assortis et indépendants. Les deux gènes dominants S et P confèrent aux plantes une importante pilosité sur les tiges et sur les pétioles tandis qu'un allèle dominant S-pp et ss-P confère aux plantes une pilosité respectivement abondante sur les tiges st sur les pétioles. Seuls les génotypes homozygotes sspp avec deux gènes récessifs produisent des plantes avec peu de poils sur les tiges et sur les pétioles. Les implications de ces résultats dans l'évolution de ces espèces sont discutées.

  8. Gestion des agroecosystemes sur le mont agou en zone forestiere ...

    African Journals Online (AJOL)

    Dans le but d'une meilleure mise en valeur de l'espace, plusieurs espèces végétales sont cultivées en association essentiellement avec Persea americana. L'approche méthodologique est basée sur des inventaires floristiques et écologiques sur 45 placettes de 25 m x 25 m dans les agrosystèmes. Une diversité de 85 ...

  9. Taxes sur les cigarettes en Tanzanie | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    On s'attend à ce que cette hausse du tabagisme ait d'importantes répercussions sur la santé publique et le développement économique. Il ressort de l'expérience d'autres régions que le moyen le plus efficace de renverser une telle tendance consiste à augmenter les taxes sur les cigarettes. Toutefois, les responsables des ...

  10. Increasing the darkfield contrast-to-noise ratio using a deconvolution-based information retrieval algorithm in X-ray grating-based phase-contrast imaging.

    Science.gov (United States)

    Weber, Thomas; Pelzer, Georg; Bayer, Florian; Horn, Florian; Rieger, Jens; Ritter, André; Zang, Andrea; Durst, Jürgen; Anton, Gisela; Michel, Thilo

    2013-07-29

    A novel information retrieval algorithm for X-ray grating-based phase-contrast imaging based on the deconvolution of the object and the reference phase stepping curve (PSC) as proposed by Modregger et al. was investigated in this paper. We applied the method for the first time on data obtained with a polychromatic spectrum and compared the results to those, received by applying the commonly used method, based on a Fourier analysis. We confirmed the expectation, that both methods deliver the same results for the absorption and the differential phase image. For the darkfield image, a mean contrast-to-noise ratio (CNR) increase by a factor of 1.17 using the new method was found. Furthermore, the dose saving potential was estimated for the deconvolution method experimentally. It is found, that for the conventional method a dose which is higher by a factor of 1.66 is needed to obtain a similar CNR value compared to the novel method. A further analysis of the data revealed, that the improvement in CNR and dose efficiency is due to the superior background noise properties of the deconvolution method, but at the cost of comparability between measurements at different applied dose values, as the mean value becomes dependent on the photon statistics used.

  11. Contrast-enhanced peripheral MRA. Technique and contrast agents

    International Nuclear Information System (INIS)

    Nielsen, Yousef W.; Thomsen, Henrik S.

    2012-01-01

    In the last decade contrast-enhanced magnetic resonance angiography (CE-MRA) has gained wide acceptance as a valuable tool in the diagnostic work-up of patients with peripheral arterial disease. This review presents current concepts in peripheral CE-MRA with emphasis on MRI technique and contrast agents. Peripheral CE-MRA is defined as an MR angiogram of the arteries from the aortic bifurcation to the feet. Advantages of CE-MRA include minimal invasiveness and lack of ionizing radiation. The basic technique employed for peripheral CE-MRA is the bolus-chase method. With this method a paramagnetic MRI contrast agent is injected intravenously and T1-weighted images are acquired in the subsequent arterial first-pass phase. In order to achieve high quality MR angiograms without interfering venous contamination or artifacts, a number of factors need to be taken into account. This includes magnetic field strength of the MRI system, receiver coil configuration, use of parallel imaging, contrast bolus timing technique, and k-space filling strategies. Furthermore, it is possible to optimize peripheral CE-MRA using venous compression techniques, hybrid scan protocols, time-resolved imaging, and steady-state MRA. Gadolinium(Gd)-based contrast agents are used for CE-MRA of the peripheral arteries. Extracellular Gd agents have a pharmacokinetic profile similar to iodinated contrast media. Accordingly, these agents are employed for first-pass MRA. Blood-pool Gd-based agents are characterized by prolonged intravascular stay, due to macromolecular structure or protein binding. These agents can be used for first-pass, as well as steady-state MRA. Some Gd-based contrast agents with low thermodynamic stability have been linked to development of nephrogenic systemic fibrosis in patients with severe renal insufficiency. Using optimized technique and a stable MRI contrast agent, peripheral CE-MRA is a safe procedure with diagnostic accuracy close to that of conventional catheter X

  12. Simulation of single grid-based phase-contrast x-ray imaging (g-PCXI)

    Energy Technology Data Exchange (ETDEWEB)

    Lim, H.W.; Lee, H.W. [Department of Radiation Convergence Engineering, iTOMO Group, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon-do 26493 (Korea, Republic of); Cho, H.S., E-mail: hscho1@yonsei.ac.kr [Department of Radiation Convergence Engineering, iTOMO Group, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon-do 26493 (Korea, Republic of); Je, U.K.; Park, C.K.; Kim, K.S.; Kim, G.A.; Park, S.Y.; Lee, D.Y.; Park, Y.O.; Woo, T.H. [Department of Radiation Convergence Engineering, iTOMO Group, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon-do 26493 (Korea, Republic of); Lee, S.H.; Chung, W.H.; Kim, J.W.; Kim, J.G. [R& D Center, JPI Healthcare Co., Ltd., Ansan 425-833 (Korea, Republic of)

    2017-04-01

    Single grid-based phase-contrast x-ray imaging (g-PCXI) technique, which was recently proposed by Wen et al. to retrieve absorption, scattering, and phase-gradient images from the raw image of the examined object, seems a practical method for phase-contrast imaging with great simplicity and minimal requirements on the setup alignment. In this work, we developed a useful simulation platform for g-PCXI and performed a simulation to demonstrate its viability. We also established a table-top setup for g-PCXI which consists of a focused-linear grid (200-lines/in strip density), an x-ray tube (100-μm focal spot size), and a flat-panel detector (48-μm pixel size) and performed a preliminary experiment with some samples to show the performance of the simulation platform. We successfully obtained phase-contrast x-ray images of much enhanced contrast from both the simulation and experiment and the simulated contract seemed similar to the experimental contrast, which shows the performance of the developed simulation platform. We expect that the simulation platform will be useful for designing an optimal g-PCXI system. - Highlights: • It is proposed for the single grid-based phase-contrast x-ray imaging (g-PCXI) technique. • We implemented for a numerical simulation code. • The preliminary experiment with several samples to compare is performed. • It is expected to be useful to design an optimal g-PCXI system.

  13. Influence du système de logement sur quelques performances ...

    African Journals Online (AJOL)

    Les effets de deux systèmes de logement (batterie de cages et sol sur litière) sur les performances zootechniques et économiques des poules pondeuses ont été évalués en zone tropicale humide, au sud du Benin. Un total de 180 poules pondeuses (Isa Brown) de 26 semaines d'âge était réparti en deux groupes de 108 et ...

  14. Low-Molecular-Weight Iron Chelates May Be an Alternative to Gadolinium-based Contrast Agents for T1-weighted Contrast-enhanced MR Imaging.

    Science.gov (United States)

    Boehm-Sturm, Philipp; Haeckel, Akvile; Hauptmann, Ralf; Mueller, Susanne; Kuhl, Christiane K; Schellenberger, Eyk A

    2018-02-01

    Purpose To synthesize two low-molecular-weight iron chelates and compare their T1 contrast effects with those of a commercial gadolinium-based contrast agent for their applicability in dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging. Materials and Methods The animal experiments were approved by the local ethics committee. Two previously described iron (Fe) chelates of pentetic acid (Fe-DTPA) and of trans-cyclohexane diamine tetraacetic acid (Fe-tCDTA) were synthesized with stability constants several orders of magnitude higher than those of gadolinium-based contrast agents. The T1 contrast effects of the two chelates were compared with those of gadopentetate dimeglumine in blood serum phantoms at 1.5 T, 3 T, and 7 T. For in vivo studies, a human breast cancer cell line (MDA-231) was implanted in five mice per group. The dynamic contrast effects of the chelates were compared by performing DCE MR imaging with intravenous application of Fe-DTPA or Fe-tCDTA on day 1 and DCE MR imaging in the same tumors with gadopentetate dimeglumine on day 2. Quantitative DCE maps were generated with software and were compared by means of a one-tailed Pearson correlation test. Results Relaxivities in serum (0.94 T at room temperature) of Fe-tCDTA (r1 = 2.2 mmol -1 · sec -1 , r2 = 2.5 mmol -1 · sec -1 ) and Fe-DTPA (r1 = 0.9 mmol -1 · sec -1 , r2 = 0.9 mmol -1 · sec -1 ) were approximately twofold and fivefold lower, respectively, compared with those of gadopentetate dimeglumine (r1 = 4.1 mmol -1 · sec -1 , r2 = 4.8 mmol -1 · sec -1 ). Used at moderately higher concentrations, however, iron chelates generated similar contrast effects at T1-weighted MR imaging in vitro in serum, in vivo in blood, and for DCE MR imaging of breast cancer xenografts. The volume transfer constant values for Fe-DTPA and Fe-tCDTA in the same tumors correlated well with those observed for gadopentetate dimeglumine (Fe-tCDTA Pearson R, 0.99; P = .0003; Fe-DTPA Pearson R, 0.97; P

  15. Analyser-based phase contrast image reconstruction using geometrical optics.

    Science.gov (United States)

    Kitchen, M J; Pavlov, K M; Siu, K K W; Menk, R H; Tromba, G; Lewis, R A

    2007-07-21

    Analyser-based phase contrast imaging can provide radiographs of exceptional contrast at high resolution (geometrical optics are satisfied. Analytical phase retrieval can be performed by fitting the analyser rocking curve with a symmetric Pearson type VII function. The Pearson VII function provided at least a 10% better fit to experimentally measured rocking curves than linear or Gaussian functions. A test phantom, a hollow nylon cylinder, was imaged at 20 keV using a Si(1 1 1) analyser at the ELETTRA synchrotron radiation facility. Our phase retrieval method yielded a more accurate object reconstruction than methods based on a linear fit to the rocking curve. Where reconstructions failed to map expected values, calculations of the Takagi number permitted distinction between the violation of the geometrical optics conditions and the failure of curve fitting procedures. The need for synchronized object/detector translation stages was removed by using a large, divergent beam and imaging the object in segments. Our image acquisition and reconstruction procedure enables quantitative phase retrieval for systems with a divergent source and accounts for imperfections in the analyser.

  16. Enhancement of Edge-based Image Quality Measures Using Entropy for Histogram Equalization-based Contrast Enhancement Techniques

    Directory of Open Access Journals (Sweden)

    H. T. R. Kurmasha

    2017-12-01

    Full Text Available An Edge-based image quality measure (IQM technique for the assessment of histogram equalization (HE-based contrast enhancement techniques has been proposed that outperforms the Absolute Mean Brightness Error (AMBE and Entropy which are the most commonly used IQMs to evaluate Histogram Equalization based techniques, and also the two prominent fidelity-based IQMs which are Multi-Scale Structural Similarity (MSSIM and Information Fidelity Criterion-based (IFC measures. The statistical evaluation results show that the Edge-based IQM, which was designed for detecting noise artifacts distortion, has a Person Correlation Coefficient (PCC > 0.86 while the others have poor or fair correlation to human opinion, considering the Human Visual Perception (HVP. Based on HVP, this paper propose an enhancement to classic Edge-based IQM by taking into account the brightness saturation distortion which is the most prominent distortion in HE-based contrast enhancement techniques. It is tested and found to have significantly well correlation (PCC > 0.87, Spearman rank order correlation coefficient (SROCC > 0.92, Root Mean Squared Error (RMSE < 0.1054, and Outlier Ratio (OR = 0%.

  17. Reconfiguración de la Cooperación Sur-Sur en la región latinoamericana y la participación internacional de los actores subnacionales

    Directory of Open Access Journals (Sweden)

    Mariana Calvento

    2015-01-01

    Full Text Available El presente trabajo describe y analiza las actua-les características de la Cooperación Sur-Sur en América Latina, especialmente el papel de los actores subnacionales en dicha dinámica. A su vez, analiza las modalidades que adquiere esta cooperación en el contexto político regio-nal de la última década, donde se evidencia un importante avance de la integración de los países latinoamericanos. Finalmente, estudila relación existente entre los principios de la Cooperación Sur-Sur con la participación in-ternacional de los actores subnacionales a partir de la relevancia que adquieren algunas de es-tas formas de cooperación, como es el caso de la Red mercociudades, el Foro Consultivo de Municipios, Estados Federados, Provincias y Departamentos del mercosur (fccr mer-cosur y la Federación Latinoamericana de Ciudades, Municipios y Asociaciones de Go-biernos Locales (flacma, que nuclean a estos actores y promueven mecanismos institucionales que favorecen la participación de las ciudades a través de diferentes instrumentos de intercambio y cooperación.

  18. Controverses sur les sucres [Controversies about sugars

    Directory of Open Access Journals (Sweden)

    Malika BOUCHENAK

    2016-12-01

    Full Text Available La surconsommation de sucres ajoutés et leurs effets putatifs sur diverses pathologies cardiométaboliques continuent de susciter des controverses. Dans les années 1950, le taux élevé de maladies cardiovasculaires (MCV, chez les hommes Américains a conduit à des études sur le rôle des facteurs alimentaires, tels que le cholestérol, les phytostérols, l'excès de calories, les acides aminés, les graisses, les glucides, les vitamines et les minéraux, à influencer le risque de MCV. Dans les années 60, deux éminents physiologistes, plaidant pour des hypothèses causales divergentes de MCV, John Yudkin a identifié les sucres ajoutés comme agent primaire, tandis que Ancel Keys identifiait les graisses totales, les graisses saturées et le cholestérol alimentaire. Cependant, dans les années 80, peu de scientifiques croyaient que les sucres ajoutés jouaient un rôle important dans la maladie coronarienne, et les premiers conseils nutritionnels de 1980 (1980 Dietary Guidelines for americans étaient axés sur la réduction des graisses totales, des graisses saturées et du cholestérol alimentaire pour la prévention des MCV.

  19. High-energy x-ray grating-based phase-contrast radiography of human anatomy

    Science.gov (United States)

    Horn, Florian; Hauke, Christian; Lachner, Sebastian; Ludwig, Veronika; Pelzer, Georg; Rieger, Jens; Schuster, Max; Seifert, Maria; Wandner, Johannes; Wolf, Andreas; Michel, Thilo; Anton, Gisela

    2016-03-01

    X-ray grating-based phase-contrast Talbot-Lau interferometry is a promising imaging technology that has the potential to raise soft tissue contrast in comparison to conventional attenuation-based imaging. Additionally, it is sensitive to attenuation, refraction and scattering of the radiation and thus provides complementary and otherwise inaccessible information due to the dark-field image, which shows the sub-pixel size granularity of the measured object. Until recent progress the method has been mainly limited to photon energies below 40 keV. Scaling the method to photon energies that are sufficient to pass large and spacious objects represents a challenging task. This is caused by increasing demands regarding the fabrication process of the gratings and the broad spectra that come along with the use of polychromatic X-ray sources operated at high acceleration voltages. We designed a setup that is capable to reach high visibilities in the range from 50 to 120 kV. Therefore, spacious and dense parts of the human body with high attenuation can be measured, such as a human knee. The authors will show investigations on the resulting attenuation, differential phase-contrast and dark-field images. The images experimentally show that X-ray grating-based phase-contrast radiography is feasible with highly absorbing parts of the human body containing massive bones.

  20. Contrast Materials

    Science.gov (United States)

    ... is mixed with water before administration liquid paste tablet When iodine-based and barium-sulfate contrast materials ... for patients with kidney failure or allergies to MRI and/or computed tomography (CT) contrast material. Microbubble ...

  1. La estrategia de liderazgo regional de la India a través de la cooperación sur-sur (2003-2012)

    OpenAIRE

    Jaime Garzón, Carlos Felipe

    2014-01-01

    La presente investigación tiene como objetivo analizar en qué medida la estrategia de liderazgo regional de la India ha sido impulsada a través de los programas y proyectos de cooperación sur-sur ofrecidos por este país en el periodo de 2003-2012. De igual forma se pretende indagar sobre el papel histórico que ha jugado la India en el establecimiento y posterior evolución de esta nueva forma de cooperación que ha sido vista por la mayoría de los académicos como un complemento de la cooperació...

  2. Enjeux de territoires sur une frontière méconnue

    Directory of Open Access Journals (Sweden)

    Françoise Grenand

    2012-11-01

    Full Text Available « J’ai travaillé dans le temps sur le chantier d’un pont sur le Zambèze. Je me suis toujours demandé pourquoi ils avaient décidé de faire un pont à cet endroit : c’est la même chose sur les deux rives… ». Humphrey Bogart, in African Queen, de John Huston, 1951.Il y a encore quatre décennies, la Guyane ignorait superbement qu’elle eût un voisin nommé Brésil. Une frontière en commun ? Et même la plus longue frontière terrestre de la France ? Les deux seules librairies du département ne proposai...

  3. SurF: an innovative framework in biosecurity and animal health surveillance evaluation.

    Science.gov (United States)

    Muellner, Petra; Watts, Jonathan; Bingham, Paul; Bullians, Mark; Gould, Brendan; Pande, Anjali; Riding, Tim; Stevens, Paul; Vink, Daan; Stärk, Katharina Dc

    2018-05-16

    Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system. Surveillance evaluation should be an integral part of the surveillance life cycle, as it provides a means to identify and correct problems and to sustain and enhance the existing strengths of a surveillance system. The surveillance evaluation Framework (SurF) presented here was developed to provide a generic framework within which the MPI biosecurity surveillance portfolio, and all of its components, can be consistently assessed. SurF is an innovative, cross-sectoral effort that aims to provide a common umbrella for surveillance evaluation in the animal, plant, environment and aquatic sectors. It supports the conduct of the following four distinct components of an evaluation project: (i) motivation for the evaluation, (ii) scope of the evaluation, (iii) evaluation design and implementation and (iv) reporting and communication of evaluation outputs. Case studies, prepared by MPI subject matter experts, are included in the framework to guide users in their assessment. Three case studies were used in the development of SurF in order to assure practical utility and to confirm usability of SurF across all included sectors. It is anticipated that the structured approach and information provided by SurF will not only be of benefit to MPI but also to other New Zealand stakeholders. Although SurF was developed for internal use by MPI, it could be applied to any surveillance system in New Zealand or elsewhere. © 2018 2018 The Authors. Transboundary and Emerging Diseases Published by Blackwell Verlag GmbH.

  4. Los rubios. Recherche sur les différents états de la mémoire et sur la reconstruction d’une identité

    Directory of Open Access Journals (Sweden)

    Marta Mariasole Raimondi

    2010-11-01

    Full Text Available Los rubios, Argentina, 2003. Réalisation : Albertina Carri. Interprètes : Analìa Couceyro, Albertina Carri. Durée : 89 min. Noir & blanc et couleurs. Langue espagnole. Introduction Mélange de souvenirs, d’anecdotes, de fragments et d’imagination. Los rubios [trad. Les Blonds] ne se présente pas comme un film de dénonciation ou comme un documentaire historique sur les detenidos-desparecidos. Dans ce film, Albertina Carri propose plutôt sa vision personnelle sur la disparition de ses parents. L...

  5. Sur la plurifonctionnalité du discours direct

    Directory of Open Access Journals (Sweden)

    Cigada Sara

    2012-07-01

    Full Text Available La comparaison entre les résultats de nombreux travaux sur le dialogue dans le texte littéraire, sur l’attestation linguistique de la subjectivité, sur la fonction argumentative des émotions dans le discours et sur les effets de polyphonie, suggère que la structure sémiotique et linguistique du discours direct (DD se trouve au croisement stratégique de plusieurs axes de la construction discursive. Nous étudions donc l’insertion du DD dans le discours (cf. Rosier 2008: Le discours rapporté en français; Kerbrat 2005: Le Discours en interaction et Id. 2008: Le Dialogue comme objet d’analyse linguistique; Maingueneau 2010: Manuel de linguistique pour le texte littéraire en tant que phénomène de rupture sémiotique (Genette 1972: Figures III et Id. 1983: Nouveau discours du récit, dans ses fonctions discursives plurielles, tantôt émotives (Tannen 1989: Talking Voices; Plantin-Traverso-Vosghanian 2008: Parcours des émotions en interaction, tantôt argumentatives (Doury 2001: La Fonction argumentative des échanges rapportés; Stati 1990: Le transphrastique. Du point de vue méthodologique, nous nous proposons de revisiter empiriquement, par l'étude de corpus, les traits linguistiques structuraux qui caractérisent l’insertion du DD dans un récit à l'écrit, en les comparant systématiquement aux traits de l’insertion du DD dans un récit à l'oral. Une analyse parallèle est possible en ce qui concerne les fonctions discursives, que le DD typiquement déroule dans les récits. Les fonctions du DD décrites à partir de l'étude des corpus sont plurielles: on reconnaît des fonctions fortement argumentatives d'autres plus typiquement narratives, tandis que d'autres encore amalgament les deux fonctions. Le « contrat de littéralité », qui selon Genette ne porterait jamais que sur la teneur du discours, doit donc être fortement nuancé selon les contextes, tandis que l'effet de sens le plus directement lié à la

  6. Feature and Contrast Enhancement of Mammographic Image Based on Multiscale Analysis and Morphology

    Directory of Open Access Journals (Sweden)

    Shibin Wu

    2013-01-01

    Full Text Available A new algorithm for feature and contrast enhancement of mammographic images is proposed in this paper. The approach bases on multiscale transform and mathematical morphology. First of all, the Laplacian Gaussian pyramid operator is applied to transform the mammography into different scale subband images. In addition, the detail or high frequency subimages are equalized by contrast limited adaptive histogram equalization (CLAHE and low-pass subimages are processed by mathematical morphology. Finally, the enhanced image of feature and contrast is reconstructed from the Laplacian Gaussian pyramid coefficients modified at one or more levels by contrast limited adaptive histogram equalization and mathematical morphology, respectively. The enhanced image is processed by global nonlinear operator. The experimental results show that the presented algorithm is effective for feature and contrast enhancement of mammogram. The performance evaluation of the proposed algorithm is measured by contrast evaluation criterion for image, signal-noise-ratio (SNR, and contrast improvement index (CII.

  7. GSTAR-SUR Modeling With Calendar Variations And Intervention To Forecast Outflow Of Currencies In Java Indonesia

    Science.gov (United States)

    Akbar, M. S.; Setiawan; Suhartono; Ruchjana, B. N.; Riyadi, M. A. A.

    2018-03-01

    Ordinary Least Squares (OLS) is general method to estimates Generalized Space Time Autoregressive (GSTAR) parameters. But in some cases, the residuals of GSTAR are correlated between location. If OLS is applied to this case, then the estimators are inefficient. Generalized Least Squares (GLS) is a method used in Seemingly Unrelated Regression (SUR) model. This method estimated parameters of some models with residuals between equations are correlated. Simulation study shows that GSTAR with GLS method for estimating parameters (GSTAR-SUR) is more efficient than GSTAR-OLS method. The purpose of this research is to apply GSTAR-SUR with calendar variation and intervention as exogenous variable (GSTARX-SUR) for forecast outflow of currency in Java, Indonesia. As a result, GSTARX-SUR provides better performance than GSTARX-OLS.

  8. Dans le labyrinthe de verre. La négociation sur l'effet de serre

    OpenAIRE

    Hourcade , Jean Charles

    2002-01-01

    National audience; En parcourant les étapes principales de la « négociation climat », on fait apparaître le jeu de miroirs qui se déroule entre Europe et États-Unis, dans un contexte historique caractérisé par les débats sur la mondialisation, la volonté de leadership de l'Union européenne sur ce thème, la montée aux États-Unis d'inquiétudes sur le maintien de leur suprématie.On montre aussi pourquoi ce jeu, après avoir masqué des possibilités réelles de compromis, a débouché en 2000 sur l'éc...

  9. Sur les lherzolites et ophites des Pyrénées

    NARCIS (Netherlands)

    Zwart, H.J.

    1953-01-01

    Depuis longtemps on trouve dans la littérature sur la géologie des Pyrénées des discussions sur les lherzolites et les ophites, concernant leur origine, leur âge et leur mode de formation. En général ces discussions ont rendu difficile l'éclaircissement de ce problème et un résumé de toute la

  10. L'incidence des pesticides sur les producteurs de pommes de terre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 janv. 2011 ... De 1990 à 1993, lui et Charles Crissman du Centre international de la pomme de terre (CIP) en Équateur ont participé à une étude appelée Tradeoffs qui portait sur les effets des pesticides sur la santé, l'environnement et la productivité. Tous deux sont chargés de la direction des recherches du projet ...

  11. Turismo en Segovia sur. Análisis y propuestas de mejora

    OpenAIRE

    Herranz Marcos, María

    2015-01-01

    Este trabajo hace un análisis sobre el turismo rural y sostenible. El cual se basa en el territorio de Segovia sur. Segovia sur tiene un gran potencial turístico, que en algunas zonas es menos conocido. Por ello la creación de una serie de propuestas (senderismo, cicloturismo) que de forma sostenible potencien el desarrollo del turismo en esa zona. Grado en Turismo

  12. Etude des répercussions de la pollution industrielle sur la riziculture ...

    African Journals Online (AJOL)

    Les industries spécialisées dans le textile déversent leurs eaux usées dans le ... sur les sols, les compositions chimiques des plants de riz et sur la production. ... The effluents quality varies on day, the pH from 3.9 to 10.6 and the electrical ...

  13. Contrast-based sensorless adaptive optics for retinal imaging.

    Science.gov (United States)

    Zhou, Xiaolin; Bedggood, Phillip; Bui, Bang; Nguyen, Christine T O; He, Zheng; Metha, Andrew

    2015-09-01

    Conventional adaptive optics ophthalmoscopes use wavefront sensing methods to characterize ocular aberrations for real-time correction. However, there are important situations in which the wavefront sensing step is susceptible to difficulties that affect the accuracy of the correction. To circumvent these, wavefront sensorless adaptive optics (or non-wavefront sensing AO; NS-AO) imaging has recently been developed and has been applied to point-scanning based retinal imaging modalities. In this study we show, for the first time, contrast-based NS-AO ophthalmoscopy for full-frame in vivo imaging of human and animal eyes. We suggest a robust image quality metric that could be used for any imaging modality, and test its performance against other metrics using (physical) model eyes.

  14. Effects of gadolinium-based MRI contrast agents on liver tissue.

    Science.gov (United States)

    Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Topal Suzan, Zehra; Çinar, Seda; Akyildiz, Kerimali; Mercantepe, Filiz; Yilmaz, Adnan

    2018-04-01

    MRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. To compare the effects on liver tissue of gadolinium-based MRI contrast agents in the light of biochemical and histopathological evaluation. Institutional Review Board (IRB)-approved controlled longitudinal study. In all, 32 male Sprague-Dawley rats were divided into a healthy control group subjected to no procedure (Group 1), a sham group (Group 2), a gadodiamide group (Group 3), and a gadoteric acid group (Group 4). Not applicable. Liver tissues removed at the end of the fifth week and evaluated pathologically (scored Knodell's histological activity index [HAI] method by two histopathologists) immunohistochemical (caspase-3 and biochemical tests (AST, ALT, TAS, TOS, and OSI method by Erel et al) were obtained. Differences between groups were analyzed using the nonparametric Kruskal-Wallis test followed by the Tamhane test, and one-way analysis of variance (ANOVA) followed by Turkey's HSD test. An increase was observed in histological activity scores in sections from rats administered gadodiamide and gadoteric acid, and in caspase-3, AST and ALT values (P total antioxidant and antioxidant capacity. 1 Technical Efficacy: Stage 4 J. Magn. Reson. Imaging 2018. © 2018 International Society for Magnetic Resonance in Medicine.

  15. Cooperación Sur-Sur para el fortalecimiento de los laboratorios de control de medicamentos de la Comunidad del Caribe (CARICOM

    Directory of Open Access Journals (Sweden)

    José María Parisi

    Full Text Available RESUMEN Objetivo Describir los beneficios obtenidos a través de la cooperación Sur-Sur y Triangular, como una potencial herramienta para el fortalecimiento en el control de la calidad de los medicamentos en los Laboratorios Oficiales de Control de Medicamentos (LOCM de la Región de las Américas. Métodos Estudio descriptivo del proyecto para el fortalecimiento en el control de la calidad de los medicamentos en los LOCM de la Comunidad del Caribe (CARICOM. Resultados La capacitación fue desarrollada por profesionales de la Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT de Argentina, a profesionales de Guyana, Jamaica, Surinam y Trinidad y Tobago. El proyecto contó con financiamiento del Fondo Argentino de Cooperación Sur-Sur y Triangular (FO.AR y coordinación de la Organización Panamericana de la Salud (OPS. Se revisaron los documentos de Buenas Prácticas de Laboratorio (BPL de la Organización Mundial de la Salud (OMS y de la Red Panamericana para la Armonización de la Reglamentación Farmacéutica (Red-PARF y se fortaleció el área de controles físicos químicos, principalmente en relación a medicamentos para el tratamiento de la tuberculosis, la malaria y el VIH/sida, todos de importancia estratégica para esos países. Conclusión Este tipo de colaboraciones permiten transferir experiencia, optimizar los recursos, armonizar procedimientos y regulaciones y reforzar capacidades en término de recursos humanos, y constituyen una herramienta valiosa en la reducción de las asimetrías que pudieron establecerse en diferentes áreas entre diferentes países de nuestra región.

  16. Experiments with the SUR 100 training reactor

    International Nuclear Information System (INIS)

    Milicic, B.

    1984-06-01

    This paper contains a compilation of various experiments using the SUR - 100 reactor for training purposes, which have been widly proved in practical work at the School for Nuclear Technology of the Karlsruhe Research Center. (orig.) [de

  17. Analyser-based phase contrast image reconstruction using geometrical optics

    International Nuclear Information System (INIS)

    Kitchen, M J; Pavlov, K M; Siu, K K W; Menk, R H; Tromba, G; Lewis, R A

    2007-01-01

    Analyser-based phase contrast imaging can provide radiographs of exceptional contrast at high resolution (<100 μm), whilst quantitative phase and attenuation information can be extracted using just two images when the approximations of geometrical optics are satisfied. Analytical phase retrieval can be performed by fitting the analyser rocking curve with a symmetric Pearson type VII function. The Pearson VII function provided at least a 10% better fit to experimentally measured rocking curves than linear or Gaussian functions. A test phantom, a hollow nylon cylinder, was imaged at 20 keV using a Si(1 1 1) analyser at the ELETTRA synchrotron radiation facility. Our phase retrieval method yielded a more accurate object reconstruction than methods based on a linear fit to the rocking curve. Where reconstructions failed to map expected values, calculations of the Takagi number permitted distinction between the violation of the geometrical optics conditions and the failure of curve fitting procedures. The need for synchronized object/detector translation stages was removed by using a large, divergent beam and imaging the object in segments. Our image acquisition and reconstruction procedure enables quantitative phase retrieval for systems with a divergent source and accounts for imperfections in the analyser

  18. L'Avenir de la Vie sur la Terre

    CERN Document Server

    CERN. Geneva

    2007-01-01

    Notre planète va mal : réchauffement climatique, épuisement des ressources naturelles, pollutions des sols et de l'eau provoquées par les industries civiles et guerrières, disparité des richesses, malnutrition des hommes, taux d'extinction effarant des espèces vivantes, etc. La situation est-elle vraiment dramatique ? Que penser des thèses qui contestent ce pessimisme ? À partir des données scientifiques les plus crédibles - et de leurs incertitudes -, Hubert Reeves dresse un bilan précis des menaces qui pèsent sur la planète. Son diagnostic est alarmant : si la vie sur Terre est robuste, c'est l'avenir de l'espèce humaine qui est en cause. Le sort de l'aventure humaine, entamée il y a des millions d'années, va-t-il se jouer en l'espace de quelques décennies ? Notre avenir est entre nos mains. Il faut réagir, et vite, avant qu'il ne soit trop tard. Auteur de nombreux ouvrages sur l'odyssée cosmique tel Patience dans l'azur ou Poussières d'étoiles, Hubert Reeves est astrophysicien et dire...

  19. Breast tumor segmentation in high resolution x-ray phase contrast analyzer based computed tomography.

    Science.gov (United States)

    Brun, E; Grandl, S; Sztrókay-Gaul, A; Barbone, G; Mittone, A; Gasilov, S; Bravin, A; Coan, P

    2014-11-01

    Phase contrast computed tomography has emerged as an imaging method, which is able to outperform present day clinical mammography in breast tumor visualization while maintaining an equivalent average dose. To this day, no segmentation technique takes into account the specificity of the phase contrast signal. In this study, the authors propose a new mathematical framework for human-guided breast tumor segmentation. This method has been applied to high-resolution images of excised human organs, each of several gigabytes. The authors present a segmentation procedure based on the viscous watershed transform and demonstrate the efficacy of this method on analyzer based phase contrast images. The segmentation of tumors inside two full human breasts is then shown as an example of this procedure's possible applications. A correct and precise identification of the tumor boundaries was obtained and confirmed by manual contouring performed independently by four experienced radiologists. The authors demonstrate that applying the watershed viscous transform allows them to perform the segmentation of tumors in high-resolution x-ray analyzer based phase contrast breast computed tomography images. Combining the additional information provided by the segmentation procedure with the already high definition of morphological details and tissue boundaries offered by phase contrast imaging techniques, will represent a valuable multistep procedure to be used in future medical diagnostic applications.

  20. La Convention de Rio sur la diversité biologique

    OpenAIRE

    Maljean-Dubois , Sandrine

    2016-01-01

    International audience; Du 3 au 14 juin 1992, en écho à la première grande conférence onusienne sur l'environnement et le développement, celle de Stockholm organisée en 1972, se tenait à Rio de Janeiro la Conférence des Nations Unies sur l'environnement et le développement (CNUED), dite aussi Sommet de la Terre. Cette conférence marquait une étape dans la perception des enjeux environnementaux et suscitait de vifs espoirs. Un programme d'action pour le XXI ème siècle, Action 21, dont le chapi...

  1. Effets du travail du sol sur le comportement chimique et biologique ...

    African Journals Online (AJOL)

    SARAH

    31 juil. 2017 ... RESUME. Objectif : L'objectif de cette étude est de comparer les effets de six techniques culturales de mise en place du blé tendre sur certaines propriétés chimiques et biologiques du sol et les conséquences sur le rendement grain et ses composantes dans la région «non chernozem» en 7ème années ...

  2. Altiplano Sur de Bolivia : capítulo 5.1.b

    OpenAIRE

    Winkel, Thierry; Alvarez-Flores, R.; Bommel, P.; Bourliaud, J.; Chevarria Lazo, M.; Cortes, G.; Cruz, P.; Del Castillo, C.; Gasselin, P.; Joffre, R.; Léger, F.; Nina Laura, J.P.; Rambal, S.; Rivière, G.; Tichit, M.

    2014-01-01

    Alimento de base de las poblaciones andinas desde hace milenios, la quinua se ha convertido hoy en un producto apreciado en el mercado internacional de alimentos dietéticos, orgánicos y equitativos. Este cambio lo iniciaron los mismos productores del Altiplano Sur de Bolivia hace aproximadamente unos 40 años. En medio de un desierto de altura, ellos lograron desarrollar una floreciente producción agrícola de exportación. Aunque cuentan con lucrativos nichos de mercado, los productores de quin...

  3. Contrast-enhanced harmonic endoscopic ultrasound

    DEFF Research Database (Denmark)

    Săftoiu, A; Dietrich, C F; Vilmann, P

    2012-01-01

    Second-generation intravenous blood-pool ultrasound contrast agents are increasingly used in endoscopic ultrasound (EUS) for characterization of microvascularization, differential diagnosis of benign and malignant focal lesions, and improving staging and guidance of therapeutic procedures. Although...... initially used as Doppler signal enhancers, second-generation microbubble contrast agents are now used with specific contrast harmonic imaging techniques, which benefit from the highly nonlinear behavior of the microbubbles. Contrast-specific modes based on multi-pulse technology are used to perform...... contrast-enhanced harmonic EUS based on a very low mechanical index (0.08 - 0.12). Quantification techniques based on dynamic contrast-enhanced ultrasound have been recommended for perfusion imaging and monitoring of anti-angiogenic treatment, mainly based on time-intensity curve analysis. Most...

  4. Sur?Surva - the Forgotten God [In Bulgarian

    Directory of Open Access Journals (Sweden)

    G. Simeonova

    2014-12-01

    Full Text Available Тhis paper deals with the neglected god – Sur/Surva. The author considers in full detail this problem, finding an evidence for the statements proposed by a new perusal of Stefan Verkovich’s Veda Slovena.

  5. A speeded-up saliency region-based contrast detection method for small targets

    Science.gov (United States)

    Li, Zhengjie; Zhang, Haiying; Bai, Jiaojiao; Zhou, Zhongjun; Zheng, Huihuang

    2018-04-01

    To cope with the rapid development of the real applications for infrared small targets, the researchers have tried their best to pursue more robust detection methods. At present, the contrast measure-based method has become a promising research branch. Following the framework, in this paper, a speeded-up contrast measure scheme is proposed based on the saliency detection and density clustering. First, the saliency region is segmented by saliency detection method, and then, the Multi-scale contrast calculation is carried out on it instead of traversing the whole image. Second, the target with a certain "integrity" property in spatial is exploited to distinguish the target from the isolated noises by density clustering. Finally, the targets are detected by a self-adaptation threshold. Compared with time-consuming MPCM (Multiscale Patch Contrast Map), the time cost of the speeded-up version is within a few seconds. Additional, due to the use of "clustering segmentation", the false alarm caused by heavy noises can be restrained to a lower level. The experiments show that our method has a satisfied FASR (False alarm suppression ratio) and real-time performance compared with the state-of-art algorithms no matter in cloudy sky or sea-sky background.

  6. Use of Iodine-based contrast media in digital full-field mammography - initial experience

    International Nuclear Information System (INIS)

    Diekmann, F.; Diekmann, S.; Taupitz, M.; Bick, U.; Winzer, K.-J.; Huettner, C.; Muller, S.; Jeunehomme, F.; Hamm, B.

    2003-01-01

    Aim: To investigate the use of iodine-based contrast media in digital full-field mammography. Methods: After performing initial phantom studies, seven patients underwent digital mammography (Senographe 2000D, GE Medical Systems, Milwaukee, USA) using a specially filtered beam before as well as 60, 120, and 180 seconds after injection of 80 ml of iodine contrast medium (Ultravist 370, Schering AG, Germany). The precontrast mammograms were then subtracted from the postcontrast mammograms and the resulting images compared with a contrast-enhanced dynamic MRI study, performed on all women. Results: Contrast medium accumulation within the tumors was visualized with a good quality in all cases. The conditions under which successful contrast-enhanced digital mammography can be performed were determined in phantom studies. Conclusions: Contrast-enhanced digital mammography has a potential for improving the visualization of breast tumors in mammography using special beam filtering, adjusted X-ray parameters, proper timing, and suitable subtraction software. (orig.) [de

  7. Perception du risque et vulnérabilité des milieux humides sur la côte ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ils repéreront et évalueront les facteurs de stress associés aux changements climatiques pour ensuite analyser les facteurs qui influent sur la gestion des milieux humides et sur la perception des risques au sein des collectivités locales. Cette analyse débouchera sur l'élaboration de lignes directrices pour encourager les ...

  8. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

    Science.gov (United States)

    Amrani, Salah

    La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues

  9. Effets de la perfusion intensive sur quelques paramètres sanguins ...

    African Journals Online (AJOL)

    Objectif: l'objectif de cette étude est d'évaluer les effets d'une perfusion intensive chez des veaux atteints de diarrhée aiguë sur les paramètres sanguins notamment l'hématocrite, les protéines totales, la créatinine et l'urée plasmatiques, le pH, l'excès de base (BE) et le bicarbonate dans le sang. Méthodologie et résultats: ...

  10. Multipeak Mean Based Optimized Histogram Modification Framework Using Swarm Intelligence for Image Contrast Enhancement

    Directory of Open Access Journals (Sweden)

    P. Babu

    2015-01-01

    Full Text Available A novel approach, Multipeak mean based optimized histogram modification framework (MMOHM is introduced for the purpose of enhancing the contrast as well as preserving essential details for any given gray scale and colour images. The basic idea of this technique is the calculation of multiple peaks (local maxima from the original histogram. The mean value of multiple peaks is computed and the input image’s histogram is segmented into two subhistograms based on this multipeak mean (mmean value. Then, a bicriteria optimization problem is formulated and the subhistograms are modified by selecting optimal contrast enhancement parameters. While formulating the enhancement parameters, particle swarm optimization is employed to find optimal values of them. Finally, the union of the modified subhistograms produces a contrast enhanced and details preserved output image. This mechanism enhances the contrast of the input image better than the existing contemporary HE methods. The performance of the proposed method is well supported by the contrast enhancement quantitative metrics such as discrete entropy, natural image quality evaluator, and absolute mean brightness error.

  11. Sur le discours et l’histoire en foucault. Entretien avec Jacques Guilhaumou

    Directory of Open Access Journals (Sweden)

    Welisson Marques

    2013-08-01

    Full Text Available Dans cet entretien inédit, Jaques Guilhaumou parle sur la question du discours et de l´histoire dans la pensée de Michel Foucault en regardant telles questions à partir du belvédère de l’Analyse du Discours selon la perception française. Il commence en présentant un panorama de ses travaux plus actuels et souligne ensuite le rôle décisif de Foucault dans le établissement de une nouvelle relation entre le discours et l´histoire. Dans cette direction, il donne des détails sur quelques influences épistémologiques de la pensée foucaultienne qui viennent surtout de Nietzsche et Koselleck. Comme un grand étudiant de la pensée marxiste, Guilhaumou parle aussi sur le concept de l´ideologie et ses plusières métamorphoses conceptuelles dans autres champs jusqu´au moment de parler sur la question du pouvoir. Il parle quand même sur la problématique de l´analyse des images dans l´Analyse du Discours, une question favorable pour beaucoup des analystes du discours qui s´occupent avec le syncrétisme sémiotique des ses objets dans l´actualité. Enfin, il indique l´existence de une théorie du discours diluée dans la pensée du philosophe.

  12. Pouvoir et sexualité. Le discours féministe sur la prostitution en France (1968-1986.

    Directory of Open Access Journals (Sweden)

    Damien Simonin

    2010-07-01

    Full Text Available Cette recherche porte sur les discours sur la prostitution dans la presse féministe, entre 1968 et 1986 en France. Durant cette période, le mouvement féministe est composé de courants conflictuels (courants réformistes et révolutionnaires, différentialistes et universalistes et il porte des discours hétérogènes (informations sur la prostitution, analyses théoriques et politiques, témoignages de prostituées. Pourtant, ces discours s'accordent sur la revendication d'une libération des rapport...

  13. Use of small reactors as an alternative to supply electricity to Baja California Sur

    International Nuclear Information System (INIS)

    Alonso, G.; Portes, E.; Ramirez, J. R.; Ortega, G.

    2016-09-01

    The state of Baja California Sur (Mexico) does not form part of the national interconnected electrical system of the country, reason why is local its electrical power supply; one of the alternatives to cover future demands is the use of gas-based combined cycles, which presents the additional problem of including a high price for gas transportation in its costs. In order to reduce total costs, including investment, fuels and operation and maintenance in the operation of the Baja California Sur state electricity system in the coming years, mainly due to the estimated natural gas cost order of $11.50 dollars per million BTU, a proposal is presented to reduce the costs of the electrical system by replacing the necessary combined cycles with the new Small Modular Reactor type nuclear reactors, this alternative is economically competitive. (Author)

  14. Stochastic parallel gradient descent based adaptive optics used for a high contrast imaging coronagraph

    International Nuclear Information System (INIS)

    Dong Bing; Ren Deqing; Zhang Xi

    2011-01-01

    An adaptive optics (AO) system based on a stochastic parallel gradient descent (SPGD) algorithm is proposed to reduce the speckle noises in the optical system of a stellar coronagraph in order to further improve the contrast. The principle of the SPGD algorithm is described briefly and a metric suitable for point source imaging optimization is given. The feasibility and good performance of the SPGD algorithm is demonstrated by an experimental system featured with a 140-actuator deformable mirror and a Hartmann-Shark wavefront sensor. Then the SPGD based AO is applied to a liquid crystal array (LCA) based coronagraph to improve the contrast. The LCA can modulate the incoming light to generate a pupil apodization mask of any pattern. A circular stepped pattern is used in our preliminary experiment and the image contrast shows improvement from 10 -3 to 10 -4.5 at an angular distance of 2λ/D after being corrected by SPGD based AO.

  15. Marín E. y Romero M. (Eds., Cuando el Sur piensa el Sur. Los giros de la cooperación al desarrollo, Bogotá: Universidad Externado de Colombia, 364 pp.

    Directory of Open Access Journals (Sweden)

    Daniel Vargas

    2016-07-01

    Full Text Available El marco introductorio del libro indica que los Estados ubicados en África, Asia y América del Sur, comparten algunas características climáticas, geológicas, biotípicas, económicas e históricas como fuentes inagotables de diversidades identitarias. Es por esto que cobran sentido y adquieren eco las palabras de la líder Leonor Zalabata de la etnia Arhuaca de Colombia transcritas en el epígrafe de la presente reseña, quien al preguntársele por el futuro de los pueblos originarios respondió: “somos y seguiremos siendo”. Lo que significa que, al considerar que los pueblos indígenas y autóctonos son un actor común en los continentes del Sur, y afianzados en la defensa de su identidad, promueven el autodesarrollo, convirtiéndose así en un actor político relevante en los procesos de cooperación Sur-Sur.

  16. Effets du stress salin sur la germination des graines de Gossypium ...

    African Journals Online (AJOL)

    SARAH

    31 août 2014 ... herbeuses et vives tandis que 40 % des graines ont germé sur tanne arbustive en milieu réel. Conclusion et application: l'objectif général de cette étude menée en milieu contrôlé (application des doses de sel) et en milieu réel (tannes) était de montrer les effets du stress salin sur la germination des graines.

  17. Fatal anaphylactic reaction to intravenous gadobutrol, a gadolinium-based MRI contrast agent

    Directory of Open Access Journals (Sweden)

    Sabine Franckenberg, MD

    2018-02-01

    Full Text Available We present the rare case of a fatal anaphylactic reaction to gadobutrol, a magnetic resonance imaging contrast agent, in a 42-year-old man. The patient underwent elective magnetic resonance imaging for diagnostic clarification of a suspicious finding in the abdomen. The patient had undergone contrast-enhanced computed tomography previously without the occurrence of any adverse effects. Adverse drug reactions in gadobutrol have a very low prevalence of 0.32%-3.5%, with serious adverse drug reactions in <0.1%. There are only a few cases of fatal anaphylactoid reactions to gadolinium-based contrast agents in general. However, if an anaphylactoid reaction occurs, it can present itself with a fulminant course within minutes.

  18. Apprentissage en ligne et sur le tas au Mexique | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Laura Dávila est de retour sur les bancs de l'école. Installée à son bureau dans la classe virtuelle @Campus Mexico, cette fonctionnaire mexicaine se renseigne sur son propre gouvernement — ses ministères et son cadre juridique, les lois qui encadrent l'accès à l'information et la responsabilité de la fonction publique, ...

  19. Synthèse de la recherche sur les moyens de subsistance pouvant ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Synthèse de la recherche sur les moyens de subsistance pouvant remplacer la culture du tabac. Dans l'espoir de faire obstacle aux politiques visant à réduire la demande de produits du tabac, les compagnies de tabac font valoir que ces politiques auront des répercussions négatives sur l'emploi et l'économie des pays ...

  20. Incidence des prix et des taxes sur la consommation de produits du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Incidence des prix et des taxes sur la consommation de produits du tabac en Argentine, en Bolivie et au Chili. Partout en Amérique du Sud, les adultes et les enfants font une grande consommation de tabac. Un nouveau projet de recherche se penchera sur les avantages et les limites des stratégies de fixation des prix et de ...

  1. La vérite sur ce qui nous motive

    CERN Document Server

    Pink, Daniel H

    2011-01-01

    Voici enfin la traduction française du best-seller international DRIVE ! Qu'est-ce qui nous motive vraiment ? Dans quels cas sommes-nous les plus performants et les plus enthousiastes ? La plupart d'entre nous sommes persuadés que les récompenses (salaire, primes...) sont notre meilleure motivation. La logique de la carotte et du bâton finalement... Et si nous faisions fausse route ? En s'appuyant sur quatre décennies d'études scientifiques et psychologiques sur la motivation humaine, Pink démontre que les entreprises dirigent très mal leurs équipes avec d'énormes conséquences sur notre vie (absence d'ambition, lassitude, morosité). Le secret de la performance (et de la satisfaction) dans les entreprises, l'enseignement ou dans notre vie personnelle , c'est le besoin profondément humain de diriger sa propre vie, d'apprendre, de créer de nouvelles choses et de s'améliorer. Dans ce livre, Pink examine les 3 éléments de la motivation, l'autonomie, la maîtrise et le besoin de donner un sens ...

  2. Breast tumor segmentation in high resolution x-ray phase contrast analyzer based computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Brun, E., E-mail: emmanuel.brun@esrf.fr [European Synchrotron Radiation Facility (ESRF), Grenoble 380000, France and Department of Physics, Ludwig-Maximilians University, Garching 85748 (Germany); Grandl, S.; Sztrókay-Gaul, A.; Gasilov, S. [Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, 81377 Munich (Germany); Barbone, G. [Department of Physics, Harvard University, Cambridge, Massachusetts 02138 (United States); Mittone, A.; Coan, P. [Department of Physics, Ludwig-Maximilians University, Garching 85748, Germany and Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, 81377 Munich (Germany); Bravin, A. [European Synchrotron Radiation Facility (ESRF), Grenoble 380000 (France)

    2014-11-01

    Purpose: Phase contrast computed tomography has emerged as an imaging method, which is able to outperform present day clinical mammography in breast tumor visualization while maintaining an equivalent average dose. To this day, no segmentation technique takes into account the specificity of the phase contrast signal. In this study, the authors propose a new mathematical framework for human-guided breast tumor segmentation. This method has been applied to high-resolution images of excised human organs, each of several gigabytes. Methods: The authors present a segmentation procedure based on the viscous watershed transform and demonstrate the efficacy of this method on analyzer based phase contrast images. The segmentation of tumors inside two full human breasts is then shown as an example of this procedure’s possible applications. Results: A correct and precise identification of the tumor boundaries was obtained and confirmed by manual contouring performed independently by four experienced radiologists. Conclusions: The authors demonstrate that applying the watershed viscous transform allows them to perform the segmentation of tumors in high-resolution x-ray analyzer based phase contrast breast computed tomography images. Combining the additional information provided by the segmentation procedure with the already high definition of morphological details and tissue boundaries offered by phase contrast imaging techniques, will represent a valuable multistep procedure to be used in future medical diagnostic applications.

  3. Grating-based phase contrast tomosynthesis imaging: Proof-of-concept experimental studies

    International Nuclear Information System (INIS)

    Li, Ke; Ge, Yongshuai; Garrett, John; Bevins, Nicholas; Zambelli, Joseph; Chen, Guang-Hong

    2014-01-01

    Purpose: This paper concerns the feasibility of x-ray differential phase contrast (DPC) tomosynthesis imaging using a grating-based DPC benchtop experimental system, which is equipped with a commercial digital flat-panel detector and a medical-grade rotating-anode x-ray tube. An extensive system characterization was performed to quantify its imaging performance. Methods: The major components of the benchtop system include a diagnostic x-ray tube with a 1.0 mm nominal focal spot size, a flat-panel detector with 96 μm pixel pitch, a sample stage that rotates within a limited angular span of ±30°, and a Talbot-Lau interferometer with three x-ray gratings. A total of 21 projection views acquired with 3° increments were used to reconstruct three sets of tomosynthetic image volumes, including the conventional absorption contrast tomosynthesis image volume (AC-tomo) reconstructed using the filtered-backprojection (FBP) algorithm with the ramp kernel, the phase contrast tomosynthesis image volume (PC-tomo) reconstructed using FBP with a Hilbert kernel, and the differential phase contrast tomosynthesis image volume (DPC-tomo) reconstructed using the shift-and-add algorithm. Three inhouse physical phantoms containing tissue-surrogate materials were used to characterize the signal linearity, the signal difference-to-noise ratio (SDNR), the three-dimensional noise power spectrum (3D NPS), and the through-plane artifact spread function (ASF). Results: While DPC-tomo highlights edges and interfaces in the image object, PC-tomo removes the differential nature of the DPC projection data and its pixel values are linearly related to the decrement of the real part of the x-ray refractive index. The SDNR values of polyoxymethylene in water and polystyrene in oil are 1.5 and 1.0, respectively, in AC-tomo, and the values were improved to 3.0 and 2.0, respectively, in PC-tomo. PC-tomo and AC-tomo demonstrate equivalent ASF, but their noise characteristics quantified by the 3D NPS

  4. Grating-based phase contrast tomosynthesis imaging: Proof-of-concept experimental studies

    Science.gov (United States)

    Li, Ke; Ge, Yongshuai; Garrett, John; Bevins, Nicholas; Zambelli, Joseph; Chen, Guang-Hong

    2014-01-01

    Purpose: This paper concerns the feasibility of x-ray differential phase contrast (DPC) tomosynthesis imaging using a grating-based DPC benchtop experimental system, which is equipped with a commercial digital flat-panel detector and a medical-grade rotating-anode x-ray tube. An extensive system characterization was performed to quantify its imaging performance. Methods: The major components of the benchtop system include a diagnostic x-ray tube with a 1.0 mm nominal focal spot size, a flat-panel detector with 96 μm pixel pitch, a sample stage that rotates within a limited angular span of ±30°, and a Talbot-Lau interferometer with three x-ray gratings. A total of 21 projection views acquired with 3° increments were used to reconstruct three sets of tomosynthetic image volumes, including the conventional absorption contrast tomosynthesis image volume (AC-tomo) reconstructed using the filtered-backprojection (FBP) algorithm with the ramp kernel, the phase contrast tomosynthesis image volume (PC-tomo) reconstructed using FBP with a Hilbert kernel, and the differential phase contrast tomosynthesis image volume (DPC-tomo) reconstructed using the shift-and-add algorithm. Three inhouse physical phantoms containing tissue-surrogate materials were used to characterize the signal linearity, the signal difference-to-noise ratio (SDNR), the three-dimensional noise power spectrum (3D NPS), and the through-plane artifact spread function (ASF). Results: While DPC-tomo highlights edges and interfaces in the image object, PC-tomo removes the differential nature of the DPC projection data and its pixel values are linearly related to the decrement of the real part of the x-ray refractive index. The SDNR values of polyoxymethylene in water and polystyrene in oil are 1.5 and 1.0, respectively, in AC-tomo, and the values were improved to 3.0 and 2.0, respectively, in PC-tomo. PC-tomo and AC-tomo demonstrate equivalent ASF, but their noise characteristics quantified by the 3D NPS

  5. A user-friendly LabVIEW software platform for grating based X-ray phase-contrast imaging.

    Science.gov (United States)

    Wang, Shenghao; Han, Huajie; Gao, Kun; Wang, Zhili; Zhang, Can; Yang, Meng; Wu, Zhao; Wu, Ziyu

    2015-01-01

    X-ray phase-contrast imaging can provide greatly improved contrast over conventional absorption-based imaging for weakly absorbing samples, such as biological soft tissues and fibre composites. In this study, we introduced an easy and fast way to develop a user-friendly software platform dedicated to the new grating-based X-ray phase-contrast imaging setup at the National Synchrotron Radiation Laboratory of the University of Science and Technology of China. The control of 21 motorized stages, of a piezoelectric stage and of an X-ray tube are achieved with this software, it also covers image acquisition with a flat panel detector for automatic phase stepping scan. Moreover, a data post-processing module for signals retrieval and other custom features are in principle available. With a seamless integration of all the necessary functions in one software package, this platform greatly facilitate users' activities during experimental runs with this grating based X-ray phase contrast imaging setup.

  6. Quelques noddees sur l’ecologie de la vedetation des dunes et sur la fonction de l’enraciment dans l’edification de dunes a la Cote Mediterraneenne de la France. I

    NARCIS (Netherlands)

    Boterenbrood, A.J.; Donsellaar-Ten Bokkel Huinink, van W.A.E.; Donselaar, van J.

    1956-01-01

    Dans la végétation des dunes du Languedoc J. BRAUN-BLANQUET (1952) distingue trois associations, à savoir; 1) l’Agropyretum mediterraneum parmi et sur les premières dunes basses; 2) l’Ammophiletum arundinaceae sur les dunes plus hautes; et 3) le Crucianelletum maritimae dans les dépressions et en

  7. Optimization of X-ray phase-contrast imaging based on in-line holography

    International Nuclear Information System (INIS)

    Wu Xizeng; Liu Hong; Yan Aimin

    2005-01-01

    This paper introduces a newly conceived formalism for clinical in-line phase-contrast X-ray imaging. The new formalism applies not only to ideal 'thin' objects analyzed in previous studies, but also applies to the real-world tissues used in actual clinical practice. Moreover we have identified the four clinically important factors that affect phase-contrast characteristics. These factors are: (1) body part attenuation (2) the spatial coherence of incident X-rays from an X-ray tube (3) the polychromatic nature of the X-ray source and (4) radiation dose to patients for clinical applications. Techniques of phase image-reconstruction based on the new X-ray in-line holography theory are discussed. Numerical simulations are described which were used to validate the theory. The design parameters of an optimal clinical phase-contrast mammographic imaging system which were determined based on the new theory, and validated in the simulations, are presented. The theory, image reconstruction algorithms, and numerical simulation techniques presented in this paper can be applied widely to clinical diagnostic X-ray imaging applications

  8. Image contrast enhancement based on a local standard deviation model

    International Nuclear Information System (INIS)

    Chang, Dah-Chung; Wu, Wen-Rong

    1996-01-01

    The adaptive contrast enhancement (ACE) algorithm is a widely used image enhancement method, which needs a contrast gain to adjust high frequency components of an image. In the literature, the gain is usually inversely proportional to the local standard deviation (LSD) or is a constant. But these cause two problems in practical applications, i.e., noise overenhancement and ringing artifact. In this paper a new gain is developed based on Hunt's Gaussian image model to prevent the two defects. The new gain is a nonlinear function of LSD and has the desired characteristic emphasizing the LSD regions in which details are concentrated. We have applied the new ACE algorithm to chest x-ray images and the simulations show the effectiveness of the proposed algorithm

  9. Plateforme régionale sur les ordinateurs personnels, déchets ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institution. SUR Corporación de Estudios Sociales y Educación. Pays d' institution. Chili. Contenus connexes. Un numéro spécial de la revue met en lumière les conclusions d'une étude financée par le CRDI sur le travail rémunéré des femmes. Policy in Focus publie un numéro spécial présentant des données probantes ...

  10. Impacts de l'exploitation artisanale de l'or sur les ressources ...

    African Journals Online (AJOL)

    L'exploitation de l'or est devenue ces deux dernières années l'activité principale de la population de Kéméni, une localité située dans la Préfecture de Tchaoudjo (Région Centrale du Togo). La présente étude a identifié l'impact de cette activité sur les ressources naturelles. L'approche méthodologique s'est basée sur des ...

  11. Dynamic vision based on motion-contrast: changes with age in adults.

    Science.gov (United States)

    Wist, E R; Schrauf, M; Ehrenstein, W H

    2000-10-01

    Data are presented for a computerized test of dynamic vision in a sample of 1006 healthy subjects aged between 20 and 85 years. The test employed a form-from-motion stimulus: i.e., within a random-dot display, Landolt rings of the same average luminance as their surroundings become visible only when the dots within the ring are moved briefly, while those of the surround remain stationary. Thus, detection of gap location is based upon motion contrast (form-from-motion) rather than luminance contrast. With the size and exposure duration of the centrally presented ring held constant, motion contrast was manipulated by varying the percentage (between 20 and 100%) of moving dots within the ring. Subjects reported gap location (left, right, top, bottom). A gradual decline of dynamic vision with age was found for all motion-contrast levels. Beyond 70 years of age, chance-level performance occurred in almost half of the subjects. The data provide the basis for applications including diagnostic screening for glaucoma, visual disturbances in brain-damaged patients, as well as assessment of the dynamic vision of drivers of motor vehicles and athletes.

  12. Spline based iterative phase retrieval algorithm for X-ray differential phase contrast radiography.

    Science.gov (United States)

    Nilchian, Masih; Wang, Zhentian; Thuering, Thomas; Unser, Michael; Stampanoni, Marco

    2015-04-20

    Differential phase contrast imaging using grating interferometer is a promising alternative to conventional X-ray radiographic methods. It provides the absorption, differential phase and scattering information of the underlying sample simultaneously. Phase retrieval from the differential phase signal is an essential problem for quantitative analysis in medical imaging. In this paper, we formalize the phase retrieval as a regularized inverse problem, and propose a novel discretization scheme for the derivative operator based on B-spline calculus. The inverse problem is then solved by a constrained regularized weighted-norm algorithm (CRWN) which adopts the properties of B-spline and ensures a fast implementation. The method is evaluated with a tomographic dataset and differential phase contrast mammography data. We demonstrate that the proposed method is able to produce phase image with enhanced and higher soft tissue contrast compared to conventional absorption-based approach, which can potentially provide useful information to mammographic investigations.

  13. Patrones biogeográficos de la avifauna de la Sierra Madre del Sur Biogeographic patterns of the avifauna of the Sierra Madre del Sur

    Directory of Open Access Journals (Sweden)

    Epifanio Blancas-Calva

    2010-08-01

    Full Text Available Analizamos la avifauna de 26 subcuencas de la provincia biótica de la Sierra Madre del Sur y sus relaciones biogeográficas utilizando el análisis de parsimonia de endemismos (PAE. A partir de información distributional de las especies obtenida de la base de datos del Atlas de las aves de México y de la literatura disponible, construimos una matriz de datos para 26 subcuencas y 437 especies. Se obtuvo un cladograma que sugiere la existencia de 3 grupos de subcuencas: el primero agrupa subcuencas de climas áridos, ubicadas geográficamente de norte a sureste en el estado de Oaxaca; el segundo, otras subcuencas de ambientes climáticos subhúmedos, y el tercero, las restantes subcuencas de ambientes climáticos húmedos de mayor complejidad ambiental.We analyzed the avifauna of 26 sub-basins of the Sierra Madre del Sur biotic province and their biogeographical relationships applying a parsimony analysis of endemicity (PAE. Based on the distributional information of the species obtained from the Atlas de las aves de México and published literature, we built a data matrix for 26 sub-basins and 437 species. The single cladogram obtained suggests the existence of three groups of sub-basins:the first with 5 sub-basins from arid environments, geographically located in north-southeastern Oaxaca; the second with another 5 sub-basins form subhumid environments; and the third one with the remaining sub-basins, from humid and environmentally more complex habitats.

  14. The effects of X-ray energy and an iodine-based contrast agent on chromosome aberrations

    International Nuclear Information System (INIS)

    Matsubara, Sho; Kubota, Nobuo; Katoh, Tsuguhisa; Yoshino, Norio; Sasaki, Takehito; Sasaki, Masao S.

    1994-01-01

    A study was undertaken to evaluate the effect of combining irradiation with X rays of various energies and an iodine-based contrast agent on the induction of chromosome aberrations in the peripheral lymphocytes of blood samples taken from healthy young donors. Although no enhancement of the effect of radiation was induced when blood samples with the iodine-based contrast agent were given 35 kV X irradiation, an 80 kV X-ray exposure induced an enhanced level of chromosome aberrations, and a 250 kV X irradiation, an enhancement of the frequencies of chromosome aberrations was seen in blood samples with the iodine-based contrast agent, especially when a Lucite phantom was employed in studies to increase the scattered rays. It was thus shown by microdosimetric analysis that X irradiation combined with an iodine-based contrast agent causes an enhancement of the absorbed radiation dose, which is dependent on the X-ray energies employed. This phenomenon may have clinical use in the radiotherapeutic management of tumors, although further extensive studies of tumor vascularity must be pursued before this can be applied clinically. 21 refs., 8 figs., 3 tabs

  15. Effet sur la compétitivité des réglementations relatives à la gestion des effluents

    DEFF Research Database (Denmark)

    Andersen, Mikael Skou

    2004-01-01

    Grâce à un regard approfondi sur le secteur laitier dans les pays de l'OCDE, cette étude permet de mieux analyser l'impact des subventions à l'agriculture et des politiques de l'environnement sur l'environnement et sur la compétitivité internationale des produits laitiers. Ce chapitre étudie les ...

  16. A second-order orientation-contrast stimulus for population-receptive-field-based retinotopic mapping.

    Science.gov (United States)

    Yildirim, Funda; Carvalho, Joana; Cornelissen, Frans W

    2018-01-01

    Visual field or retinotopic mapping is one of the most frequently used paradigms in fMRI. It uses activity evoked by position-varying high luminance contrast visual patterns presented throughout the visual field for determining the spatial organization of cortical visual areas. While the advantage of using high luminance contrast is that it tends to drive a wide range of neural populations - thus resulting in high signal-to-noise BOLD responses - this may also be a limitation, especially for approaches that attempt to squeeze more information out of the BOLD response, such as population receptive field (pRF) mapping. In that case, more selective stimulation of a subset of neurons - despite reduced signals - could result in better characterization of pRF properties. Here, we used a second-order stimulus based on local differences in orientation texture - to which we refer as orientation contrast - to perform retinotopic mapping. Participants in our experiment viewed arrays of Gabor patches composed of a foreground (a bar) and a background. These could only be distinguished on the basis of a difference in patch orientation. In our analyses, we compare the pRF properties obtained using this new orientation contrast-based retinotopy (OCR) to those obtained using classic luminance contrast-based retinotopy (LCR). Specifically, in higher order cortical visual areas such as LO, our novel approach resulted in non-trivial reductions in estimated population receptive field size of around 30%. A set of control experiments confirms that the most plausible cause for this reduction is that OCR mainly drives neurons sensitive to orientation contrast. We discuss how OCR - by limiting receptive field scatter and reducing BOLD displacement - may result in more accurate pRF localization as well. Estimation of neuronal properties is crucial for interpreting cortical function. Therefore, we conclude that using our approach, it is possible to selectively target particular neuronal

  17. Analyse du vent sur l'aérodrome de Brasov-Ghimbav (Roumanie

    Directory of Open Access Journals (Sweden)

    Marian Ilie Briceag

    2011-01-01

    Full Text Available Cette analyse du vent est destinée à préciser les conditions météorologiques locales qui conditionnent le fonctionnement de l'aérodrome de Brasov-Ghimbav. En aviation, la direction et l'intensité du vent sont très importantes pour le décollage et plus encore pour l'atterrissage des aéronefs. L'étude de cet élément météorologique est réalisée à partir d'une analyse climatologique portant sur 39 années, de 1971 à 2009, et d'une analyse aérologique sur 10 années, de 2000 à 2009 (les observations météorologiques ont été fournies par l'Administration Nationale de la Météorologie. Les résultats obtenus montrent la distribution prédominante du vent selon certaines directions, les directions nord-ouest et sud-ouest, pour les observations visuelles anciennes, et les directions ouest-nord-ouest et sud-sud-ouest, pour les observations automatiques au cours des six dernières années. Quelle que soit la méthode d'observation, c'est le vent de travers (directions ouest qui atteint les vitesses les plus élevées sur la piste principale de l'aérodrome de Brasov-Ghimbav, comme du reste sur la piste projetée pour le futur aéroport international de Brasov. Cela constitue un problème pour les aéronefs les plus légers, dont les valeurs limites pour le vent de travers sont faibles. Dans ce contexte, la prévision des vents violents est très importante. La distribution horaire des vents sur la période 2000­2009, montre notamment qu'au printemps et en été, les vents de nord-ouest sont largement dominants durant le jour, en particulier pour les vitesses [10-15 m/s, avec une fréquence maximale entre 10 et 15 heures. L'analyse aérologique des situations météorologiques apporte des éléments d'explication à certaines observations. Ainsi les vitesses du vent ≥ 20 m/s ont été enregistrées majoritairement en présence du cyclone Islandais, lors du passage du front atmosphérique froid, le contraste barrique étant

  18. Bilan du programme autrichien de recherche sur les paysages

    Directory of Open Access Journals (Sweden)

    Karolina Begusch-Pfefferkorn

    2009-03-01

    Full Text Available Austrian Landscape Research, a programme of the Austrian Ministry of Science, has created scientific foundations for the sustainable development of Austrian landscapes and regions (plus bordering regions. Landscapes and regions were to be explored from different angles; implementing the research findings was to be part of the research work. The programme was designed to make room for science open to society, for unconventional ideas, methods, and courses of action. Programmatic targets and research principles supported this intent. The results of the programme met with national and international approval. The ALR knowledge balance is an attempt at presenting and assessing the achievements of this comprehensive contract research programme.Le programme du Ministère autrichien des Sciences, intitulé « Recherche sur le paysage autrichien », visait à construire les fondements scientifiques d’un développement durable des paysages et des régions de l’Autriche et des territoires limitrophes. Les paysages et les régions ont été étudiés selon différentes approches disciplinaires et la mise en pratique des résultats de cette étude était partie prenante du programme de recherche. La vocation de ce programme était de faire la place à une science ouverte sur la société, à des idées, méthodes et pratiques non conventionnelles. Les objectifs du programme et les principes de recherche vont dans le sens de ces exigences. Les résultats du programme ont été reconnus sur le plan national et international. Le bilan des connaissances du programme de recherche sur le paysage autrichien (KLF a pour but de présenter et d’évaluer les performances de ce vaste programme de recherche.

  19. Dégâts des bruches sur le pouvoir germinatif des graines de quatre ...

    African Journals Online (AJOL)

    SARAH

    29 févr. 2016 ... cultures vivrières de base en Afrique Occidentale et centrale (MULEBA et al., 1997). En RD Congo il est ... correspondant à deux cycles de reproduction, avec des trous ou des œufs sur elles. Les trous ... tout simplement de déterminer le nombre des bruches et leurs espèces à charger dans chaque boite ...

  20. EFFET DU GETTERING SUR LA LONGUEUR DE DIFFUSION DES PLAQUETTES DE SILICIUM SEMICRISTALLIN "SOPLIN"

    Directory of Open Access Journals (Sweden)

    A MOUHOUB

    2003-06-01

    Full Text Available L’effet des diffusions du phosphore à haute température (T = 900°C sur la longueur de diffusion (Ln des plaquettes de silicium semicristallin SOPLIN (SOlidification by PLanar INterface est déterminé par la mesure de la réponse spectrale de la photopile réalisée sur le matériau traité. L’influence de ces recuits sur les paramètres photovoltaïques est enregistrée dans les caractéristiques courant - tension sous éclairement simulé et la réponse spectrale.

  1. PERSOREC : un système personnalisé de recommandations pour les folksonomies basé sur les concepts quadratiques

    OpenAIRE

    Jelassi , Mohamed Nader; Ben Yahia , Sadok; Mephu Nguifo , Engelbert

    2015-01-01

    National audience; Ce papier présente un nouveau système personnalisé de recommandations pour les folksonomies basé sur les concepts quadratiques.; This paper introduces a new personalized recommender system for folksonomies based on quadratic concepts.

  2. Contrast-enhanced spectral mammography based on a photon-counting detector: quantitative accuracy and radiation dose

    Science.gov (United States)

    Lee, Seungwan; Kang, Sooncheol; Eom, Jisoo

    2017-03-01

    Contrast-enhanced mammography has been used to demonstrate functional information about a breast tumor by injecting contrast agents. However, a conventional technique with a single exposure degrades the efficiency of tumor detection due to structure overlapping. Dual-energy techniques with energy-integrating detectors (EIDs) also cause an increase of radiation dose and an inaccuracy of material decomposition due to the limitations of EIDs. On the other hands, spectral mammography with photon-counting detectors (PCDs) is able to resolve the issues induced by the conventional technique and EIDs using their energy-discrimination capabilities. In this study, the contrast-enhanced spectral mammography based on a PCD was implemented by using a polychromatic dual-energy model, and the proposed technique was compared with the dual-energy technique with an EID in terms of quantitative accuracy and radiation dose. The results showed that the proposed technique improved the quantitative accuracy as well as reduced radiation dose comparing to the dual-energy technique with an EID. The quantitative accuracy of the contrast-enhanced spectral mammography based on a PCD was slightly improved as a function of radiation dose. Therefore, the contrast-enhanced spectral mammography based on a PCD is able to provide useful information for detecting breast tumors and improving diagnostic accuracy.

  3. L'objectivation et la perfection des femmes dans la publicité. La perception des consommateurs vis-à-vis des femmes représentées dans des campagnes publicitaires et ses effets sur la marque et sur eux-mêmes.

    OpenAIRE

    Van Dessel, Sophie; Loir, Estelle

    2017-01-01

    Depuis son apparition, la publicité contribue consciemment ou inconsciemment au changement de perception du corps de la femme. Dans la société occidentale, utiliser le corps de la femme pour inciter à l’achat d’un produit est une pratique commune dans le marketing. Un ensemble d’effets en tous genres sont à observer sur la perception des consommateurs à propos du produit et sur la marque, sur leur perception vis-à-vis des mannequins et des femmes en général et finalement sur la perception qu’...

  4. Renforcement des capacités de recherche sur les TIC-D au Moyen ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La recherche sur les incidences et les impacts des technologies de l'information et de la communication (TIC) sur le développement social et humain est embryonnaire au Moyen-Orient et en Afrique du Nord (région MOAN). Ce projet vise à encourager les chercheurs de la région MOAN à entreprendre des recherches ...

  5. L'urbanisation sur le plateau d'allada au sud-Benin, agent des ...

    African Journals Online (AJOL)

    La méthodologie adoptée pour mener à bien cette étude est basée d'une part, sur la revue documentaire et d'autre part, sur les enquêtes de terrain menées dans toutes les communes du département de l'Atlantique. La recherche documentaire a permis de cerner les contours de l'urbanisation et d'évaluer son ampleur ...

  6. Produire des données probantes sur l'agriculture sexospécifique ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le secteur agricole joue un rôle clé dans le tissu social et l'économie de ... il est important de comprendre la façon dont la dynamique sexospécifique influe sur ... aux ressources et le contrôle de celles-ci; l'emploi du temps et la main-d'œuvre; ... IWRA/CRDI sur les changements climatiques et la gestion adaptive de l'eau.

  7. Recherches sur les courants ésotériques occidentaux modernes

    OpenAIRE

    Faivre, Antoine

    2009-01-01

    Conférences de la première heure Elles ont porté principalement sur deux ouvrages récents relevant de la spécialité. Le premier, de Helmut Zander (Anthroposophie in Deutschland. Theosophische Weltanschauung und gesellschaftliche Praxis 1884‑1945, 2 vol., Vandenhoeck & Ruprecht, Göttingen 2007), fort documenté, nous a donné l’occasion de faire le point sur l’état actuel de la recherche en matière d’Anthroposophie steinerienne et de Société Théosophique. Mais nous avons commenté surtout un sous...

  8. MATLAB for laser speckle contrast analysis (LASCA): a practice-based approach

    Science.gov (United States)

    Postnikov, Eugene B.; Tsoy, Maria O.; Postnov, Dmitry E.

    2018-04-01

    Laser Speckle Contrast Analysis (LASCA) is one of the most powerful modern methods for revealing blood dynamics. The experimental design and theory for this method are well established, and the computational recipie is often regarded to be trivial. However, the achieved performance and spatial resolution may considerable differ for different implementations. We comprise a minireview of known approaches to the spatial laser speckle contrast data processing and their realization in MATLAB code providing an explicit correspondence to the mathematical representation, a discussion of available implementations. We also present the algorithm based on the 2D Haar wavelet transform, also supplied with the program code. This new method provides an opportunity to introduce horizontal, vertical and diagonal speckle contrasts; it may be used for processing highly anisotropic images of vascular trees. We provide the comparative analysis of the accuracy of vascular pattern detection and the processing times with a special attention to details of the used MATLAB procedures.

  9. Rapport annuel au Parlement Loi sur l'accès à l'information Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    leonardi

    accès à l'information. Source. Nombre de demandes. 0. Médias. 1. Rapport statistique sur la Loi sur l'accès à l'information. Nom de l'institution : Centre de recherches pour le développement international. Période visée par le ...

  10. Inmigración alemana en el sur de Chile, siglo XIX

    OpenAIRE

    Winkler, Lisette

    2009-01-01

    Presentación (en español) Durante aproximadamente un mes de trabajo de campo en Chile, Lisette Winkler (EScoM-FMSH) ha grabado una serie de entrevistas que les hizo a los descendientes de los colonos alemanes quienes se instalaron en los alrededores del lago Llanquihue en el siglo XIX. Los documentos audiovisuales fueron recopilados en dos aldeas del sur del país, Frutillar y Puerto Octay. Recogen tanto testimonios orales de los descendientes como tomas panorámicas de los paisajes del sur, qu...

  11. Contrast-to-noise ratio optimization for a prototype phase-contrast computed tomography scanner

    International Nuclear Information System (INIS)

    Müller, Mark; Yaroshenko, Andre; Velroyen, Astrid; Tapfer, Arne; Bech, Martin; Pauwels, Bart; Bruyndonckx, Peter; Sasov, Alexander; Pfeiffer, Franz

    2015-01-01

    In the field of biomedical X-ray imaging, novel techniques, such as phase-contrast and dark-field imaging, have the potential to enhance the contrast and provide complementary structural information about a specimen. In this paper, a first prototype of a preclinical X-ray phase-contrast CT scanner based on a Talbot-Lau interferometer is characterized. We present a study of the contrast-to-noise ratios for attenuation and phase-contrast images acquired with the prototype scanner. The shown results are based on a series of projection images and tomographic data sets of a plastic phantom in phase and attenuation-contrast recorded with varying acquisition settings. Subsequently, the signal and noise distribution of different regions in the phantom were determined. We present a novel method for estimation of contrast-to-noise ratios for projection images based on the cylindrical geometry of the phantom. Analytical functions, representing the expected signal in phase and attenuation-contrast for a circular object, are fitted to individual line profiles of the projection data. The free parameter of the fit function is used to estimate the contrast and the goodness of the fit is determined to assess the noise in the respective signal. The results depict the dependence of the contrast-to-noise ratios on the applied source voltages, the number of steps of the phase stepping routine, and the exposure times for an individual step. Moreover, the influence of the number of projection angles on the image quality of CT slices is investigated. Finally, the implications for future imaging purposes with the scanner are discussed

  12. Effets du Cloud computing sur les relations inter-organisationnelles dans la supply chain en France

    OpenAIRE

    AGHHAVANI-SHAJARI, Benyamin

    2016-01-01

    National audience; Le cloud computing (CC) est en train de changer la façon dont les entreprises déploient et exploitent leur système d’information. 55% des entreprises françaises utilisent le Service Cloud type Software as a service (Saas). Les recherches se sont surtout focalisées sur la question de l'adoption du CC (ACC) dans une organisation ou encore sur les difficultés techniques et informatiques. À notre connaissance il existe peu de recherches portant sur l'ACC au niveau de la supply ...

  13. The evidence-based evaluation of the safety of contrast media in patients with diabetes mellitus

    International Nuclear Information System (INIS)

    Li Jixia; Huang Baosheng

    2009-01-01

    Contrast-induced nephropathy (CIN) has now been the third most common cause of acquired renal failure. Diabetes mellitus (DM), the type of contrast agent used and the intra-arterial route of administration are three important risk factors inducing CIN. The incidence rate of CIN is very high in patients with DM or renal insufficiency after iodinated contrast was administered. Unfortunately, it has not yet attracted physicians'and radiologists'sufficient attention. This paper aims to make an evidence-based evaluation of the safety and rephrotoxicity of various contrast agents when they are used in patients with DM. Usually, intravenous administration of contrast media will not cause permanent damage to the kidney in highrisk patients. Low-osmolarity contrast media is relatively safe for patients with DM only, while it takes much risk of CIN when low-osmolarity contrast media is used in patients with diabetic nephropathy or in patients of DM accompanied with renal insufficiency, for such patients, the iso-osmolarity contrast media, iodixanol, can be used. (authors)

  14. Les articles de 2017 à lire absolument sur CRDI.ca | CRDI - Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les articles de 2017 à lire absolument sur CRDI.ca. 02 janvier 2018. Le contenu le plus populaire publié cette année sur notre site Web offre un bon aperçu des défis en matière de développement revêtant une importance capitale pour nos lecteurs. Il démontre également la diversité du travail effectué par le CRDI de même ...

  15. Yarn supplier selection using analytical hierarchy process (AHP) and standardized unitless rating (SUR) method on textile industry

    Science.gov (United States)

    Erfaisalsyah, M. H.; Mansur, A.; Khasanah, A. U.

    2017-11-01

    For a company which engaged in the textile field, specify the supplier of raw materials for production is one important part of supply chain management which can affect the company's business processes. This study aims to identify the best suppliers of raw material suppliers of yarn for PC. PKBI based on several criteria. In this study, the integration between the Analytical Hierarchy Process (AHP) and the Standardized Unitless Rating (SUR) are used to assess the performance of the suppliers. By using AHP, it can be known the value of the relative weighting of each criterion. While SUR shows the sequence performance value of the supplier. The result of supplier ranking calculation can be used to know the strengths and weaknesses of each supplier based on its performance criteria. From the final result, it can be known which suppliers should improve their performance in order to create long term cooperation with the company.

  16. Urbanismo y arquitectura moderna en madera en el sur de Chile: 1930-1970

    Directory of Open Access Journals (Sweden)

    Gonzalo Cerda Brintrup

    2005-07-01

    Full Text Available La investigación que se presenta tiene como objetivos estudiar el desarrollo de la arquitectura moderna en madera en el sur de Chile; indagar acerca de como esta se incerta en la tradición maderera de la arquitectura del sur; investigar su relación con el desarrollo de una identidad arquitectónica local;localizar y analizar sus ejemplos más significativos. El área de estudio es desde la VIII hasta la X Región, específicamente desde la Provincia de Concepción hasta Chiloé, por cuanto allí se concentra la mayor parte de la arquitectura en madera del sur del país.

  17. Les différences culturelles et leur impact sur la relation soignant-soigné

    OpenAIRE

    Uysal, Ayse; Matter, Catherine

    2011-01-01

    Ce travail porte sur les différences culturelles et leur impact sur la relation soignant-soigné lors d’une hospitalisation. Ainsi la problématique de recherche est centrée sur l’identification des difficultés et des spécificités présentes lorsque le soignant entre en relation avec un patient d’une culture différente. Le but de cette étude est d’identifier les difficultés et les obstacles liés à la culture, présents dans la relation soignant-soigné. Le deuxième but est de mettre en évidence le...

  18. Influence intra-blogosphérique et visibilité sur les réseaux sociaux

    Directory of Open Access Journals (Sweden)

    Damien Renard

    2015-10-01

    Full Text Available Cette recherche vise à mieux comprendre le fonctionnement des blogueurs influents et leur rôle dans la diffusion de la connaissance culinaire sur les réseaux sociaux numériques. Nous construisons un modèle pour observer le processus d’influence, de la position du blogueur à l’intérieur de la communauté jusqu’au partage du contenu sur Facebook. A partir de l’étude quantitative de 952 blogs culinaires, nous montrons que l’influence intra-blogosphérique conditionne la stratégie éditoriale du blogueur mais également sa visibilité sur les réseaux sociaux.

  19. A new method for information retrieval in two-dimensional grating-based X-ray phase contrast imaging

    International Nuclear Information System (INIS)

    Wang Zhi-Li; Gao Kun; Chen Jian; Ge Xin; Tian Yang-Chao; Wu Zi-Yu; Zhu Pei-Ping

    2012-01-01

    Grating-based X-ray phase contrast imaging has been demonstrated to be an extremely powerful phase-sensitive imaging technique. By using two-dimensional (2D) gratings, the observable contrast is extended to two refraction directions. Recently, we have developed a novel reverse-projection (RP) method, which is capable of retrieving the object information efficiently with one-dimensional (1D) grating-based phase contrast imaging. In this contribution, we present its extension to the 2D grating-based X-ray phase contrast imaging, named the two-dimensional reverse-projection (2D-RP) method, for information retrieval. The method takes into account the nonlinear contributions of two refraction directions and allows the retrieval of the absorption, the horizontal and the vertical refraction images. The obtained information can be used for the reconstruction of the three-dimensional phase gradient field, and for an improved phase map retrieval and reconstruction. Numerical experiments are carried out, and the results confirm the validity of the 2D-RP method

  20. A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

    International Nuclear Information System (INIS)

    Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung

    2014-01-01

    Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

  1. A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung [Yonsei University, Wonju (Korea, Republic of)

    2014-06-15

    Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

  2. Inmigración alemana en el sur de Chile, siglo XIX

    Directory of Open Access Journals (Sweden)

    Lisette Winkler

    2009-01-01

    Full Text Available Presentación (en español Durante aproximadamente un mes de trabajo de campo en Chile, Lisette Winkler (EScoM-FMSH ha grabado una serie de entrevistas que les hizo a los descendientes de los colonos alemanes quienes se instalaron en los alrededores del lago Llanquihue en el siglo XIX. Los documentos audiovisuales fueron recopilados en dos aldeas del sur del país, Frutillar y Puerto Octay. Recogen tanto testimonios orales de los descendientes como tomas panorámicas de los paisajes del sur, qu...

  3. Design and Optimization of Gadolinium Based Contrast Agents for Magnetic Resonance Imaging

    International Nuclear Information System (INIS)

    Pereira, G.A.; Geraldes, C.F.G.C.; University of Coimbra

    2007-01-01

    The role of Gd 3+ chelates as contrast agents in Magnetic Resonance Imaging is discussed. The theory describing the different contributions to paramagnetic relaxation relevant to the understanding of the molecular parameters determining the relativity of those Gd 3+ chelates, is presented. The experimental techniques used to obtain those parameters are also described. Then, the various approaches taken to optimize those parameters, leading to maximum relativity (efficiency) of the contrast agents, are also illustrated with relevant examples taken from the literature. The various types of Gd 3+ -based agents, besides non-specific and hepatobiliary agents, are also discussed, namely blood pool, targeting, responsive and paramagnetic chemical shift saturation transfer (PARACEST) agents. Finally, a perspective is presented of some of the challenges lying ahead in the optimization of MRI contrast agents to be useful in Molecular Imaging. (author)

  4. Impact de la restructuration de la taxe d'accise sur le tabac aux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Aux Philippines, le taux de tabagisme est élevé et les taxes sur les produits du tabac, peu élevées. La meilleure façon de redresser la situation consiste à adopter des lois qui aug- mentent considérablement les taxes. Une loi restructurant les taxes sur les produits du tabac, qui comporte une forte hausse de la taxe d'accise ...

  5. Contrast-enhanced peripheral MRA

    DEFF Research Database (Denmark)

    Nielsen, Yousef W; Thomsen, Henrik S

    2012-01-01

    MRI contrast agent is injected intravenously and T1-weighted images are acquired in the subsequent arterial first-pass phase. In order to achieve high quality MR angiograms without interfering venous contamination or artifacts, a number of factors need to be taken into account. This includes magnetic......-state MRA. Gadolinium(Gd)-based contrast agents are used for CE-MRA of the peripheral arteries. Extracellular Gd agents have a pharmacokinetic profile similar to iodinated contrast media. Accordingly, these agents are employed for first-pass MRA. Blood-pool Gd-based agents are characterized by prolonged...... intravascular stay, due to macromolecular structure or protein binding. These agents can be used for first-pass, as well as steady-state MRA. Some Gd-based contrast agents with low thermodynamic stability have been linked to development of nephrogenic systemic fibrosis in patients with severe renal...

  6. Exogenous contrast agents for thermoacoustic imaging: An investigation into the underlying sources of contrast

    International Nuclear Information System (INIS)

    Ogunlade, Olumide; Beard, Paul

    2015-01-01

    Purpose: Thermoacoustic imaging at microwave excitation frequencies is limited by the low differential contrast exhibited by high water content tissues. To overcome this, exogenous thermoacoustic contrast agents based on gadolinium compounds, iron oxide, and single wall carbon nanotubes have previously been suggested and investigated. However, these previous studies did not fully characterize the electric, magnetic, and thermodynamic properties of these agents thus precluding identification of the underlying sources of contrast. To address this, measurements of the complex permittivity, complex permeability, DC conductivity, and Grüneisen parameter have been made. These measurements allowed the origins of the contrast provided by each substance to be identified. Methods: The electric and magnetic properties of the contrast agents were characterized at 3 GHz using two rectangular waveguide cavities. The DC conductivity was measured separately using a conductivity meter. Thermoacoustic signals were then acquired and compared to those generated in water. Finally, 3D electromagnetic simulations were used to decouple the different contributions to the absorbed power density. Results: It was found that the gadolinium compounds provided appreciable electric contrast but not originating from the gadolinium itself. The contrast was either due to dissociation of the gadolinium salt which increased ionic conductivity or its nondissociated polar fraction which increased dielectric polarization loss or a combination of both. In addition, very high concentrations were required to achieve appreciable contrast, to the extent that the Grüneisen parameter increased significantly and became a source of contrast. Iron oxide particles were found to produce low but measurable dielectric contrast due to dielectric polarization loss, but this is attributed to the coating of the particles not the iron oxide. Single wall carbon nanotubes did not provide measurable contrast of any type

  7. Exogenous contrast agents for thermoacoustic imaging: An investigation into the underlying sources of contrast

    Energy Technology Data Exchange (ETDEWEB)

    Ogunlade, Olumide, E-mail: o.ogunlade@ucl.ac.uk; Beard, Paul [Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT (United Kingdom)

    2015-01-15

    Purpose: Thermoacoustic imaging at microwave excitation frequencies is limited by the low differential contrast exhibited by high water content tissues. To overcome this, exogenous thermoacoustic contrast agents based on gadolinium compounds, iron oxide, and single wall carbon nanotubes have previously been suggested and investigated. However, these previous studies did not fully characterize the electric, magnetic, and thermodynamic properties of these agents thus precluding identification of the underlying sources of contrast. To address this, measurements of the complex permittivity, complex permeability, DC conductivity, and Grüneisen parameter have been made. These measurements allowed the origins of the contrast provided by each substance to be identified. Methods: The electric and magnetic properties of the contrast agents were characterized at 3 GHz using two rectangular waveguide cavities. The DC conductivity was measured separately using a conductivity meter. Thermoacoustic signals were then acquired and compared to those generated in water. Finally, 3D electromagnetic simulations were used to decouple the different contributions to the absorbed power density. Results: It was found that the gadolinium compounds provided appreciable electric contrast but not originating from the gadolinium itself. The contrast was either due to dissociation of the gadolinium salt which increased ionic conductivity or its nondissociated polar fraction which increased dielectric polarization loss or a combination of both. In addition, very high concentrations were required to achieve appreciable contrast, to the extent that the Grüneisen parameter increased significantly and became a source of contrast. Iron oxide particles were found to produce low but measurable dielectric contrast due to dielectric polarization loss, but this is attributed to the coating of the particles not the iron oxide. Single wall carbon nanotubes did not provide measurable contrast of any type

  8. High-contrast controllable switching based on polystyrene nonlinear cavities in 2D hole-type photonic crystals

    Science.gov (United States)

    Paghousi, Roohollah; Fasihi, Kiazand

    2018-05-01

    We present a new high-contrast controllable switch, which is based on a polystyrene nonlinear cavity, and is implemented in a two dimensional (2D) hole-type photonic crystal (PC). We show that by applying a control signal, the input power can be transmitted to the output waveguide with a high contrast ratio. The operation of the proposed device is investigated through the use of coupled-mode theory (CMT) and finite-difference time-domain (FDTD) method. The contrast ratio of the proposed device varies between 18 and 23, which is higher than the corresponding value in the previous investigations. Based on the simulation results, with increasing the control power the range of operating power will be increased, while the contrast ratio will be decreased. It has been shown that in a modified structure, at the expense of the range of operating power and the contrast ratio, the control power can be decreased, considerably.

  9. Orientations scientifiques des filles en France : un bilan contrasté Girls choosing science in France: contrasted results

    Directory of Open Access Journals (Sweden)

    Biljana Stevanovic

    2011-12-01

    Full Text Available En s’appuyant sur les enquêtes de l’Institut national de la statistique et des études économiques (INSEE et de la Direction de l’évaluation, de la prospective et de la performance (DEPP, cet article étudie l’évolution de l’orientation scientifique des filles dans l’enseignement secondaire et supérieur en France sur une période de vingt ans, de 1985 à 2008. L’objectif est d’étudier les permanences et les changements des choix des filles dans l’enseignement scientifique. Les résultats montrent que les choix d’orientation des filles vers les filières scientifiques sur la période considérée sont en nette évolution. Cette évolution est positive au niveau du secondaire mais en revanche plus ambiguë au niveau du supérieur. Le rôle joué par les politiques éducatives sur l’orientation scientifique des filles, les représentations des métiers (Mosconi & Stevanovic, 2007, le sentiment de compétence (Bandura, 1977 ; Betz & Hackett, 1981, les stéréotypes et perceptions (Armstrong & Crombi, 2000 et l’influence parentale, sont étudiés pour expliquer les liens possibles entre les représentations des sujets individuels selon leur sexe et leur décision d’une orientation scientifique.Based on surveys carried out by the INSEE (Institut National de la Statistique et des études Economiques and the DEPP (Direction de l’Evaluation de la Prospective et de la Performance, this article examines how the rate of girls choosing to study science in secondary and higher education in France evolved over a period of twenty years, from 1985 to 2008. The aim is to study continuity and change in girls’ choices into science. The findings of this study show that girls’ choices into science over the period clearly changed. There was a positive evolution at the secondary level but rather less obvious at higher education. The role of educational policies on girls’ scientific career choices, adolescents’ representations

  10. An improved contrast enhancement algorithm for infrared images based on adaptive double plateaus histogram equalization

    Science.gov (United States)

    Li, Shuo; Jin, Weiqi; Li, Li; Li, Yiyang

    2018-05-01

    Infrared thermal images can reflect the thermal-radiation distribution of a particular scene. However, the contrast of the infrared images is usually low. Hence, it is generally necessary to enhance the contrast of infrared images in advance to facilitate subsequent recognition and analysis. Based on the adaptive double plateaus histogram equalization, this paper presents an improved contrast enhancement algorithm for infrared thermal images. In the proposed algorithm, the normalized coefficient of variation of the histogram, which characterizes the level of contrast enhancement, is introduced as feedback information to adjust the upper and lower plateau thresholds. The experiments on actual infrared images show that compared to the three typical contrast-enhancement algorithms, the proposed algorithm has better scene adaptability and yields better contrast-enhancement results for infrared images with more dark areas or a higher dynamic range. Hence, it has high application value in contrast enhancement, dynamic range compression, and digital detail enhancement for infrared thermal images.

  11. Le livre sur le livre traité de documentation

    CERN Document Server

    Otlet, Paul

    2015-01-01

    Paul Otlet est considéré comme le père des sciences de l'information. Ouvrage fondateur et fondamental, le Traité de documentation. Le livre sur le livre (1934) est l'aboutissement de son travail inlassable pour rassembler, classer et partager les connaissances. Otlet y propose une remarquable synthèse du savoir sur le livre et le document en même temps qu'il anticipe Internet et l'hypertexte. La réédition du Traité de documentation, 70 ans après la disparition de son auteur, coïncide avec la réouverture du Mundaneum à Mons, où le fabuleux héritage documentaire légué par Paul Otlet et Henri La Fontaine est conservé. « Ici, la table de travail n'est plus chargée d'aucun livre. À leur place se dresse un écran et à portée un téléphone. Là-bas, au loin, dans un édifice immense, sont tous les livres et tous les renseignements. De là, on fait apparaître sur l'écran la page à lire pour connaître la réponse aux questions posées par téléphone. » Préfaces de Benoît Peeters (éc...

  12. TeleSUR: la creación televisiva de “lo latinoamericano”

    Directory of Open Access Journals (Sweden)

    Günther Maihold

    2014-06-01

    Full Text Available Nueva Televisión del Sur C. A. (Tele-SUR es el nombre de la empresa interestatal que ha iniciado sus transmisiones en el año 2005, en el marco de las nuevas iniciativas integracionistas del presidente venezolano Hugo Chávez, enfocada fundamentalmente al área noticiera para el continente americano. Concebida por su director general, el periodista uruguayo Aram Aharonian, como “alternativa a la hegemonía comunicacional, al pensamiento y la imagen únicas”, TeleSUR es parte de un proceso político más amplio, recubierto de barniz bolivariano, para reencontrar, a través de los medios electrónicos, la unidad e identidad latinoamericana frente a las grandes cadenas y corporaciones informativas internacionales, entre las cuales cuentan CNN en español, Fox News, ESPN y la BBC, con sus programas en castellano, y las grandes empresas nacionales como Televisa de México, Globo en Brasil y tanto el grupo Cisneros en Venezuela como Clarín en Argentina.

  13. Rapport de 2010 sur l'état de l'évaluation du développement en Inde ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    En Inde, des données empiriques donnent à penser que l'évaluation du développement est en déclin, tant sur le plan du nombre que de la qualité des évaluations. Toutefois, il existe très peu de données écrites, voire aucune, sur la situation de l'évaluation en Inde, ni sur les facteurs en cause. Ce projet permettra donc de ...

  14. A instrução pública na França revolucionária: considerações a partir do Essais sur l’enseignement en general et sur celui des mathématiques en particulier, de Sylvestre-François Lacroix - The public instruction in revolutionary France: some remarks accord

    Directory of Open Access Journals (Sweden)

    Antonio Vicente Marafioti Garnica

    2013-04-01

    Full Text Available O artigo aborda o livro Essais sur l'enseignement en général, et sur celui des mathématiques en particulier, de Sylvestre-François Lacroix, publicado originalmente na França em 1805, enfatizando sua primeira parte, na qual o autor discute a instrução pública e, particularmente, as escolas centrais da França revolucionária.Palavras-chave: Sylvestre-François Lacroix (1765-1843, instrução pública, Essais sur l'enseigne-ment en général, et sur celui des mathématiques en particulier, iluminismo, França. The public instruction in revolutionary France: some remarks according to Lacroix’s Essais sur l’enseignement en general et sur celui des mathématiques en particulierAbstractThe article discusses the book Essais sur l'enseignement en général, et sur celui des mathématiques en particulier, by Sylvestre-François Lacroix, originally published in France in 1805. The first part of the book, in which the author discusses public education, and particularly the central schools of revolutionary France, is emphasized.Key-words: Sylvestre-François Lacroix (1765-1843, public instruction, Essais sur l'enseignement en général, et sur celui des mathématiques en particulier, enlightenment, France. Instrucción pública en Francia revolucionaria: consideraciones a la vista del libro Essais sur l’enseignement en general et sur celui des mathématiques en particulier, de Sylvestre-François LacroixResumenEl artículo aborda el libro Essais sur l'enseignement en général, et sur celui des mathématiques en particulier de Sylvestre-François Lacroix, publicado originalmente en Francia, en 1805, haciendo hincapié en su primera parte, en la que el autor habla de la instrucción pública y en particular de las escuelas centrales en Francia en el período revolucionario.Palabras-clave: Sylvestre-François Lacroix (1765-1843, instrucción pública, Essais sur l'enseigne-ment en général, et sur celui des mathématiques en particulier

  15. Nephrogenic systemic fibrosis after application of gadolinium-based contrast agents - a status paper

    International Nuclear Information System (INIS)

    Heinrich, M.; Uder, M.

    2007-01-01

    Recently the association of a rare disease named ''nephrogenic systemic fibrosis'' (NSF) with the administration of gadolinium-containing contrast media, especially gadodiamide (Omniscan, GE-Healthcare), was described. NSF is a scleroderma-like disease characterised by widespread tissue fibrosis. Until now, NSF cases were observed only in patients with kidney disease. Almost all patients were suffering from chronic renal insufficiency, 90 % of them required renal replacement therapy. The true incidence of the disease is unknown. First retrospective analyses of selected collectives of patients with end-stage renal disease showed 2 - 5 % cases of NSF after administration of Gadolinium-containing contrast agents with an odds ratio of 20 - 50 in comparison to non-exposed controls. NSF is a serious adverse reaction, which may result in severe disabilities and even death. Therefore all radiologists applying gadolinium-based contrast agents should be informed about this disease and the recent recommendations for its prevention. On the basis of the published data, Omniscan should not be used in patients with severe renal impairment (GFR 2 ) and those who have had or are undergoing liver transplantation. In neonates and infants up to 1 year of age, Omniscan should only be used after careful consideration. Also the other gadolinium-based contrast agents should be used in high-risk patients only after careful consideration using the lowest dose possible

  16. Role of diffusion weighted imaging and dynamic contrast enhanced MR mammography to detect recurrence in breast cancer patients after sur

    Directory of Open Access Journals (Sweden)

    Safaa Ibrahim Saif El-nasr

    2016-09-01

    Conclusion: Our study showed better diagnostic performance for DCE-MRI compared to DWI in post operative breast assessment. However, DWI can provide an alternative diagnostic tool to contrast administration “if interpreted in association with conventional MR sequences” thus can be used when contrast media is contraindicated.

  17. Complications from the use of intravenous gadolinium-based contrast agents for magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Elias Junior, Jorge; Santos, Antonio Carlos dos; Nogueira-Barbosa, Marcello Henrique; Muglia, Valdair Francisco; Koenigkam-Santos, Marcel [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Hospital das Clinicas. Centro de Ciencias das Imagens e Fisica Medica]. E-mail: jejunior@fmrp.usp.br

    2008-07-15

    Gadolinium-based contrast agents are much safer than the iodinated ones; however complications may occur and should be recognized for appropriate orientation and management. The total incidence of adverse reactions to contrast agents in magnetic resonance imaging ranges between 2% and 4%. Cases of severe acute reactions to gadolinium, such as laryngospasm and anaphylactic shock, are rare. Chronic complications secondary to the use of gadolinium also can occur and, recently an association between its use and a rare dermatologic disease occurring in patients with renal failure has been reported. Nephrogenic systemic fibrosis was the subject of an official health notification issued by the American Food and Drug Administration. This progressive disease is characterized by hardened skin with fibrotic nodules and plaques which may involve other parts of the body. Patients who have been affected by this disorder presented chronic renal failure, with metabolic acidosis and had been submitted to magnetic resonance angiography, probably involving exposure to large amounts of intravenous paramagnetic contrast. This review is aimed at presenting a succinct description of the gadolinium-based contrast agent types, possible secondary complications, their preventive measures and management. (author)

  18. Institutions de recherche sur les politiques et ODD liés à la santé ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Institutions de recherche sur les politiques et ODD liés à la santé ... Ce projet permettra de tirer des enseignements sur l'utilité des think tanks pour soutenir la sensibilisation et la mobilisation des citoyens eu égard à la mise en ... Site internet.

  19. Efficacité de l'agent antagoniste Trichoderma harzianum sur ...

    African Journals Online (AJOL)

    Efficacité de l'agent antagoniste Trichoderma harzianum sur Fusarium oxysporum f. sp. lycopersiciagent pathogène de la tomate. LS Gnancadja, DHE Tonon, EMO Faton, KO Douro Kpindou, E Dannon, A Akoegninou ...

  20. Ex Vivo Perfusion-Simulation Measurements of Microbubbles as a Scattering Contrast Agent for Grating-Based X-Ray Dark-Field Imaging.

    Directory of Open Access Journals (Sweden)

    Astrid Velroyen

    Full Text Available The investigation of dedicated contrast agents for x-ray dark-field imaging, which exploits small-angle scattering at microstructures for contrast generation, is of strong interest in analogy to the common clinical use of high-atomic number contrast media in conventional attenuation-based imaging, since dark-field imaging has proven to provide complementary information. Therefore, agents consisting of gas bubbles, as used in ultrasound imaging for example, are of particular interest. In this work, we investigate an experimental contrast agent based on microbubbles consisting of a polyvinyl-alcohol shell with an iron oxide coating, which was originally developed for multimodal imaging and drug delivery. Its performance as a possible contrast medium for small-animal angiography was examined using a mouse carcass to realistically consider attenuating and scattering background signal. Subtraction images of dark field, phase contrast and attenuation were acquired for a concentration series of 100%, 10% and 1.3% to mimic different stages of dilution in the contrast agent in the blood vessel system. The images were compared to the gold-standard iodine-based contrast agent Solutrast, showing a good contrast improvement by microbubbles in dark-field imaging. This study proves the feasibility of microbubble-based dark-field contrast-enhancement in presence of scattering and attenuating mouse body structures like bone and fur. Therefore, it suggests a strong potential of the use of polymer-based microbubbles for small-animal dark-field angiography.

  1. Differential-interference-contrast digital in-line holography microscopy based on a single-optical-element.

    Science.gov (United States)

    Zhang, Yuchao; Xie, Changqing

    2015-11-01

    Both digital in-line holography (DIH) and zone plate-based microscopy have received considerable interest as powerful imaging tools. However, the former suffers from a twin-image noise problem. The latter suffers from low efficiency and difficulty in fabrication. Here, we present an effective and efficient phase-contrast imaging approach, named differential-interference-contrast digital in-line holography (DIC-DIH), by using a single optical element to split the incident light into a plane wave and a converging spherical wave and generate a two-dimensional (2D) DIC effect simultaneously. Specifically, to improve image contrast, we present a new single optical element, termed 2D DIC compound photon sieves, by combining two overlaid binary gratings and a compound photon sieve through two logical XOR operations. The proof-of-concept experiments demonstrate that the proposed technique can eliminate the twin-image noise problem and improve image contrast with high efficiency. Additionally, we present an example of the phase-contrast imaging nonuniform thick photoresist development process.

  2. Dialysis and contrast media

    International Nuclear Information System (INIS)

    Morcos, Sameh K.; Thomsen, Henrik S.; Webb, Judith A.W.

    2002-01-01

    In a previous survey we revealed uncertainty among responders about (a) whether or not to perform hemodialysis in patients with severely reduced renal function who had received contrast medium; and (b) when to perform hemodialysis in patients on regular treatment with hemodialysis or continuous ambulatory dialysis who received contrast medium. Therefore, the Contrast Media Safety Committee of The European Society of Urogenital Radiology decided to review the literature and to issue guidelines. The committee performed a Medline search. Based on this, a report and guidelines were prepared. The report was discussed at the Ninth European Symposium on Urogenital Radiology in Genoa, Italy. Hemodialysis and peritoneal dialysis safely remove both iodinated and gadolinium-based contrast media. The effectiveness of hemodialysis depends on many factors including blood and dialysate flow rate, permeability of dialysis membrane, duration of hemodialysis and molecular size, protein binding, hydrophilicity, and electrical charge of the contrast medium. Generally, several hemodialysis sessions are needed to removal all contrast medium, whereas it takes 3 weeks for continuous ambulatory dialysis to remove the agent completely. There is no need to schedule the dialysis in relation to the injection of iodinated or MR contrast media or the injection of contrast agent in relation to the dialysis program. Hemodialysis does not protect poorly functioning kidneys against contrast-medium-induced nephrotoxicity. Simple guidelines are given. (orig.)

  3. The use of innovative gadolinium-based contrast agent for MR-diagnosis of cancer in the experiment

    International Nuclear Information System (INIS)

    Chernov, V; Medvedeva, A; Sinilkin, I; Zelchan, R; Grigorev, E; Frolova, I; Nam, I

    2016-01-01

    The present study of the functional suitability and specific activity of the contrast agent gadolinium-based for magnetic resonance imaging demonstrated that the investigated contrast agent intensively accumulates in organs and anatomical structures of the experimental animals. In the model of tumor lesions in animals, study have shown that investigational contrast agent accumulates in the tumor tissue and retained there in for a long enough time. (paper)

  4. Le point sur les données ouvertes : réflexion sur leur rôle en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'ouverture de portails gouvernementaux de données ouvertes aux États-Unis et au Royaume-Uni en 2009 a été le fer de lance d'un mouvement mondial qui, près de dix ans plus tard, a été adopté par des dirigeants du monde entier, comme le montrent les objectifs de développement durable, l'accord de Paris sur le ...

  5. El impacto social de League of Legends en Corea del Sur

    OpenAIRE

    García Callealta, Desiré

    2016-01-01

    Trabajo de Fin de Máster del Máster en Asia oriental - Estudios japoneses, curso 2015-2016 [ES] Este trabajo consiste en una breve descripción y revisión bibliográfica sobre la historia de los e-Sports y su desarrollo en Corea del Sur. Debido a que se trata del primer videojuego tipo MOBA totalmente gratis que ha alcanzado la máxima popularidad en todo el mundo, League of Legends será el e-Sport central de esta exposición, si bien el impacto social que ha causado en Corea del Sur, la segun...

  6. La discussion pacifique comme rapport à la langue Française sur wikilf

    Directory of Open Access Journals (Sweden)

    Léda Mansour

    2017-07-01

    Full Text Available Cet article veut participer aux études sur le rapport des locuteurs à leur propre langue, ici la langue française. Alors que les études sur la langue pointent un lien “passionnel” qui prendra plusieurs formes: rapport puriste (parler sans faire des fautes, rapport a­ ectif (les mythes de beauté, d’ordre et de clarté, rapport idéologique (défendre sa langue, il existe, ailleurs, des lieux “pacifi ques” où la langue n’est pas disputée mais discutée. Nous avons choisi de travailler sur le site de création langagière WikiLf; c’est en créant un nouveau mot que l’on est le plus exposé à notre façon de voir/penser notre langue. Notre analyse se centre sur l’usage du métalangage laissant émerger un certain savoir sur la langue capable de traduire autrement le rapport à sa propre langue. Nous avons démontré qu’il existe un rapport plutôt spontané des locuteurs francophones qui semble dénué de toute passion, éloigné des postures normatives. Les wikistes donnent l’exemple d’une communauté qui pacifi quement met en discussion la langue française, ce qui représente d’abord un objet de réfl exion, mais encore un choix de recherche perme ant de nous positionner afi n de rendre compte (prendre en compte d’une relation plus souple des usagers de la langue française.

  7. Time-Contrastive Learning Based DNN Bottleneck Features for Text-Dependent Speaker Verification

    DEFF Research Database (Denmark)

    Sarkar, Achintya Kumar; Tan, Zheng-Hua

    2017-01-01

    In this paper, we present a time-contrastive learning (TCL) based bottleneck (BN) feature extraction method for speech signals with an application to text-dependent (TD) speaker verification (SV). It is well-known that speech signals exhibit quasi-stationary behavior in and only in a short interval......, and the TCL method aims to exploit this temporal structure. More specifically, it trains deep neural networks (DNNs) to discriminate temporal events obtained by uniformly segmenting speech signals, in contrast to existing DNN based BN feature extraction methods that train DNNs using labeled data...... to discriminate speakers or pass-phrases or phones or a combination of them. In the context of speaker verification, speech data of fixed pass-phrases are used for TCL-BN training, while the pass-phrases used for TCL-BN training are excluded from being used for SV, so that the learned features can be considered...

  8. L'IMPACT DES DEPENSES D'INFRASTRUCTURES SUR LA ...

    African Journals Online (AJOL)

    Administrateur

    l'économétrie, dans l'analyse de l'impact des dépenses d'infras- tructures sur la .... montre que les politiques budgétaires de relance peuvent avoir un impact à long terme ...... Sciences Economiques et Sciences de Gestion Université d'Alger.

  9. South Pacific Nuclear Free Zone Treaty; Tratado Sobre La Zona Desnuclearizada Del Pacifico Sur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-02-15

    On 6 August 1985 the South Pacific Forum, a body comprising the independent and self-governing countries of the South Pacific (Australia, the Cook Islands, Fiji, Kiribati, Nauru, New Zealand, Niue, Papua New Guinea, the Solomon Islands, Tonga, Tuvalu, Vanuatu and Western Samoa), endorsed the text of the South Pacific Nuclear Free Zone Treaty and opened it for signature [Spanish] El 6 de agosto de 1985 el Foro del Pacifico Sur, organo compuesto por los paises independientes y autonomos del Pacifico Sur (Australia, Fiji, Islas Cook, Islas Salomon, Kiribati, Nauru, Niue, Nueva Zelandia, Papua Nueva Guinea, Samoa Occidental, Tonga, Tuvalu, y Vanuatu), aprobo el texto del Tratado sobre la Zona Desnuclearizada del Pacifico-Sur y lo abrio a la firma.

  10. Renal function, nephrogenic systemic fibrosis and other adverse reactions associated with gadolinium-based contrast media.

    Science.gov (United States)

    Canga, Ana; Kislikova, Maria; Martínez-Gálvez, María; Arias, Mercedes; Fraga-Rivas, Patricia; Poyatos, Cecilio; de Francisco, Angel L M

    2014-01-01

    Nephrogenic systemic fibrosis is a fibrosing disorder that affects patients with impaired renal function and is associated with the administration of gadolinium-based contrast media used in MRI. Despite being in a group of drugs that were considered safe, report about this potentially serious adverse reaction was a turning point in the administration guidelines of these contrast media. There has been an attempt to establish safety parameters to identify patients with risk factors of renal failure. The close pharmacovigilance and strict observation of current regulations, with special attention being paid to the value of glomerular filtration, have reduced the published cases involving the use of gadolinium-based contrast media. In a meeting between radiologists and nephrologists we reviewed the most relevant aspects currently and recommendations for its prevention.

  11. Effet de la nutrition minérale azotée sur le gain en biomasse de l'if du canada et sur le contenu en taxanes

    OpenAIRE

    Jollez, Pierre-Antoine

    2008-01-01

    Dans le cadre d'un vaste programme de domestication de l'if du Canada (Taxus canadensis Marsh.) à des fins de production de taxanes, de jeunes plants en première, deuxième ou troisième années de culture en contenants ont été soumis à différentes sources d'azote (nitrate d'ammonium, nitrate de calcium, nitrate de sodium, sulfate d'ammonium et urée), appliquées à différentes doses, et à divers pH du substrat pour étudier leur influence sur la croissance des plants, sur la teneur en éléments min...

  12. La piraterie sur le web

    CERN Multimedia

    2002-01-01

    Les échanges de toutes sortes sont facilités à l'extrême par le web: des forums, des vidéoconférences, le commerce à distance, ou tout simplement la célérité des courriers électroniques ou la convivialité des chats, tout cela participe de la société de communication. Une certaine partie du monde découvre le nouvel horizon des échanges quasi instantanés, mais... les transactions sur le web sont-elles vraiment s res?

  13. Sur: uma minoria cosmopolita na periferia ocidental Sur: a cosmopolitan minority on the western periphery

    Directory of Open Access Journals (Sweden)

    Maria Teresa Gramuglio

    2007-06-01

    Full Text Available Este artigo explora as condições e as disposições que tornaram possível o surgimento da revista Sur e a formação do grupo cultural de mesmo nome. Propõe critérios para uma periodização que leve em conta, junto com os indícios materiais, as circunstâncias históricas e culturais cambiantes pelas quais a publicação passou durante sua longa vida (1931-1991. Assinala alguns dos principias temas ideológicos e estéticos que foram abordados em suas páginas. Caracteriza o projeto inicial e as transformações imprimidas pela vontade de sua diretora, Victoria Ocampo, e as mudanças nas relações e problemáticas do campo intelectual.This article explores the conditions and dispositions that enabled the emergence of the magazine Sur and the formation of the cultural group of the same name. It sets out the criteria for a periodization that takes into account, along with material factors, the shifting historical and cultural circumstances experienced by the publication over its 60-year life-span (1931-1991. The text highlights some of the main ideological and aesthetic themes to have filled the magazine's pages. It describes the original project and the transformations introduced by its chief editor, Victoria Ocampo, as well as the changes in the relations and problematics of the intellectual field.

  14. Parametric based morphological transformation for contrast ...

    Indian Academy of Sciences (India)

    rithm is illustrated through the processing of gray scale images and color images with different backgrounds. Keywords. Histogram equalization; image background; mathematical morphology; Weber's ratio. 1. Introduction. Contrast enhancement has a crucial role in image processing applications, such as digital.

  15. Comparative study of the ionic exchange of Ca{sup ++}, Sr{sup ++}, and Ba{sup ++} cations on resins and inorganic exchangers; Etude comparative de l'echange ionique des cations Ca{sup ++}, Sr{sup ++} et Ba{sup ++} sur resine et sur echangeurs mineraux

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Batanero, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-03-01

    With a view to applying the results to certain problems related to chemical separations in activation analysis, a study has been made, of the possibilities of separating the alkaline-earth elements Ca, Sr and Ba on organic resins and inorganic exchangers using the radioactive indicator method. The partition coefficients of the cations Ca{sup 2+}, Sr{sup 2+} and Ba{sup 2+} have been measured on Dowex 50 W (NH{sub 4}{sup +}) x 8 resin in the presence of EDTA - NTA - EGTA and DCTA as complexing agents, and on zirconium phosphate, tungstate and molybdate in the presence of HCl and NH{sub 4}Cl. Methods have been developed for separating mixtures of alkaline-earth elements using DCTA-NH{sub 4}{sup +} followed by elution on Dowex 50 W (NH{sub 4}{sup +}) x 8 resin columns and on zirconium phosphate. Amongst the complexing agents used on the ion-exchange resins the most promising appears to be DCTA which leads to partition coefficients Ca, Sr and Ba which are very different. The results of measurements of partition coefficients on zirconium phosphate (NH{sub 4}{sup +} form) using DCTA-NH{sub 4}{sup +} show the interesting possibilities of separations on columns. The separation of the alkaline-earth elements on zirconium phosphate seems to be less quantitative than on Dowex 50 resin; it is however much faster in the former case and this can be useful for treating short half-life radioisotopes in activation analysis. (author) [French] En vue de l'application a certains problemes de separations chimiques en analyse par activation, on a etudie les possibilites de separation des elements alcalino-terreux Ca-Sr et Ba sur resine organique et sur echangeurs mineraux par la methode des indicateurs radioactifs. Les coefficients de partage des cations Ca{sup +2}, Sr{sup +2} et Ba{sup +2} sur resine Dowex 50 W (NH{sub 4}{sup +}) x 8 en milieux complexants EDTA - NTA - EGTA et DCTA et sur phosphate, tungstate et molybdate de zirconium en milieu HCl et NH{sub 4}Cl ont ete mesures. Des

  16. Rapport sur le développement dans le monde sur le thème du rôle ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... rural et sont tributaires principalement de l'agriculture pour assurer leur subsistance. Ce projet permettra de veiller à ce qu'une place soit accordée aux travaux de recherche financés par le CRDI, aux points de vue différents et aux auteurs de l'hémisphère Sud dans le Rapport sur le développement dans le monde 2008.

  17. Reduced-Contrast Approximations for High-Contrast Multiscale Flow Problems

    KAUST Repository

    Chung, Eric T.; Efendiev, Yalchin

    2010-01-01

    In this paper, we study multiscale methods for high-contrast elliptic problems where the media properties change dramatically. The disparity in the media properties (also referred to as high contrast in the paper) introduces an additional scale that needs to be resolved in multiscale simulations. First, we present a construction that uses an integral equation to represent the highcontrast component of the solution. This representation involves solving an integral equation along the interface where the coefficients are discontinuous. The integral representation suggests some multiscale approaches that are discussed in the paper. One of these approaches entails the use of interface functions in addition to multiscale basis functions representing the heterogeneities without high contrast. In this paper, we propose an approximation for the solution of the integral equation using the interface problems in reduced-contrast media. Reduced-contrast media are obtained by lowering the variance of the coefficients. We also propose a similar approach for the solution of the elliptic equation without using an integral representation. This approach is simpler to use in the computations because it does not involve setting up integral equations. The main idea of this approach is to approximate the solution of the high-contrast problem by the solutions of the problems formulated in reduced-contrast media. In this approach, a rapidly converging sequence is proposed where only problems with lower contrast are solved. It was shown that this sequence possesses the convergence rate that is inversely proportional to the reduced contrast. This approximation allows choosing the reduced-contrast problem based on the coarse-mesh size as discussed in this paper. We present a simple application of this approach to homogenization of elliptic equations with high-contrast coefficients. The presented approaches are limited to the cases where there are sharp changes in the contrast (i.e., the high

  18. Computer-aided diagnosis in contrast-enhanced CT colonography: an approach based on contrast

    International Nuclear Information System (INIS)

    Luboldt, Wolfgang; Kroll, Manuela; Vogl, Thomas J.; Mann, Carolin; Vonthein, Reinhard; Stueker, Dietmar; Luz, Oliver; Claussen, Claus D.; Tryon, Cathy L.

    2002-01-01

    Automation in colorectal mass detection is achieved as soon as the voxels representing colorectal masses can be automatically segmented. We tested the Hounsfield (HU) value in intensely contrast enhanced high-resolution CT colonography for automated segmentation of colorectal masses in 18 patients with 35 polyps (28<10 mm, 7 ≥10 mm) and 7 carcinomas. Mean HU values of the colonic wall and masses were determined to deduce a gradient threshold for a segmentation process, which encodes the voxels bordering the colonic lumen with a colour ranging in intensity from 0 to 100% according to the selected gradient threshold range in the volume rendering. The results of the automated segmentation process were superimposed on a virtual double contrast and endoscopic display and validated through correlation with morphology. Mean HU values and their standard deviations for the colonic wall, polyps <10 mm, polyps ≥10 mm and carcinomas were 63±24, 154±38, 116±41 and 108±29 HU, respectively. A gradient threshold ranging from 90 to 160 HU resulted in colour pools in 6 of 7 of polyps ≥10 mm, and 6 of 7 carcinomas that were significant enough to prospectively guide the reader's attention to these masses. Due to the superposition of ''false-positive'' voxels in the projection view, the virtual endoscopic perspective was superior to the virtual double contrast display for controlling the segmentation results. The HU value is promising for automated segmentation of colorectal masses but needs to be combined with morphological parameters to render automated colorectal mass detection more accurate. Further refinements of the method with subsequent analysis of its accuracy, as well as analogue studies with contrast-enhanced MRI, appear warranted. More information at http://www.multiorganscreening.org (orig.)

  19. Immediate adverse reactions to intravenous iodinated contrast media in computed tomography Reacciones adversas inmediatas al contraste yodado intravenoso en tomografía computarizada Reações adversas imediatas ao contraste iodado intravenoso em tomografia computadorizada

    Directory of Open Access Journals (Sweden)

    Beatriz Cavalcanti Juchem

    2007-02-01

    Full Text Available This exploratory-descriptive, non-experimental quantitative research aimed to learn about immediate adverse reactions to intravenous iodinated contrast media in hospitalized patients submitted to computed tomography at a teaching hospital in the South of Brazil. During the study period, all adverse reactions showed mild intensity, at a frequency of 12.5% with ionic iodinated contrast media, and 1% with non-ionic contrast agent. The extravasation of contrast occurred in 2.2% of the injections in a peripheral vein without complications in any of the cases. The results are within the limits cited in international literature and suggest that tomography service professionals should know their own rates of adverse reactions to iodinated contrast agent, as well as the conditions in which they occur, in order to obtain evidence to evaluate the respective care delivery processes.Investigación cuantitativa del tipo exploratorio-descriptivo, de carácter no experimental. El objetivo consistía en conocer las reacciones adversas inmediatas al contraste yodado intravenoso en pacientes internados, sometidos a tomografía computarizada en un hospital escuela del sur de Brasil. Durante el período del estudio, todas las reacciones adversas tuvieron intensidad leve y una frecuencia del 12,5% con la utilización del contraste yodado iónico, y 1% con contraste no iónico. La extravasación del contraste ocurrió en un 2,2% de las inyecciones en vena periférica, no ocasionando complicaciones en ninguno de los casos. Los índices evidenciados en el presente estudio se mantuvieron dentro de los límites que constan en la revisión de literatura y, entre las recomendaciones, se sugiere que los servicios de tomografía conozcan los propios índices de reacciones adversas al contraste yodado y las condiciones en que ocurren, con la finalidad de obtener evidencias para evaluación de los respectivos procesos asistenciales.Pesquisa quantitativa, explorat

  20. Pediatric Patients Demonstrate Progressive T1-Weighted Hyperintensity in the Dentate Nucleus following Multiple Doses of Gadolinium-Based Contrast Agent.

    Science.gov (United States)

    Roberts, D R; Chatterjee, A R; Yazdani, M; Marebwa, B; Brown, T; Collins, H; Bolles, G; Jenrette, J M; Nietert, P J; Zhu, X

    2016-12-01

    While there have been recent reports of brain retention of gadolinium following gadolinium-based contrast agent administration in adults, a retrospective series of pediatric patients has not previously been reported, to our knowledge. We investigated the relationship between the number of prior gadolinium-based contrast agent doses and increasing T1 signal in the dentate nucleus on unenhanced T1-weighted MR imaging. We hypothesized that despite differences in pediatric physiology and the smaller gadolinium-based contrast agent doses that pediatric patients are typically administered based on weighted-adjusted dosing, the pediatric brain would also demonstrate dose-dependent increasing T1 signal in the dentate nucleus. We included children with multiple gadolinium-based contrast agent administrations at our institution. A blinded reader placed ROIs within the dentate nucleus and adjacent cerebellar white matter. To eliminate reader bias, we also performed automated ROI delineation of the dentate nucleus, cerebellar white matter, and pons. Dentate-to-cerebellar white matter and dentate-to pons ratios were compared with the number of gadolinium-based contrast agent administrations. During 20 years at our institution, 280 patients received at least 5 gadolinium-based contrast agent doses, with 1 patient receiving 38 doses. Sixteen patients met the inclusion/exclusion criteria for ROI analysis. Blinded reader dentate-to-cerebellar white matter ratios were significantly associated with gadolinium-based contrast agent doses (r s = 0.77, P = .001). The dentate-to-pons ratio and dentate-to-cerebellar white matter ratios based on automated ROI placement were also significantly correlated with gadolinium-based contrast agent doses (t = 4.98, P contrast agent doses is significantly correlated with progressive T1-weighted dentate hyperintensity. Definitive confirmation of gadolinium deposition requires tissue analysis. Any potential clinical sequelae of gadolinium retention in

  1. CARTOTOOL: un utilitaire de tracé de cartes sur stations de travail et micro-ordinateurs

    Directory of Open Access Journals (Sweden)

    Xavier Bemardet

    1990-05-01

    Full Text Available CARTOTOOL, logiciel interactif de tracé de cartes à différentes échelles, fonctionne, aussi bien sur écran monochrome que couleur, dans un environnement multifenêtrage SUNTOOLS. Développé pour utiliser WORLD DATA BASE II, il peut aussi tracer n'importe quel type de fichier de contours ayant un format compatible avec celui de la base. Outre ses fonctions de dessin, CARTOTOOL permet la recherche manuelle de coordonnées de points et le positionnement de relevés.

  2. Phase-only optical encryption based on the zeroth-order phase-contrast technique

    Science.gov (United States)

    Pizolato, José Carlos; Neto, Luiz Gonçalves

    2009-09-01

    A phase-only encryption/decryption scheme with the readout based on the zeroth-order phase-contrast technique (ZOPCT), without the use of a phase-changing plate on the Fourier plane of an optical system based on the 4f optical correlator, is proposed. The encryption of a gray-level image is achieved by multiplying the phase distribution obtained directly from the gray-level image by a random phase distribution. The robustness of the encoding is assured by the nonlinearity intrinsic to the proposed phase-contrast method and the random phase distribution used in the encryption process. The experimental system has been implemented with liquid-crystal spatial modulators to generate phase-encrypted masks and a decrypting key. The advantage of this method is the easy scheme to recover the gray-level information from the decrypted phase-only mask applying the ZOPCT. An analysis of this decryption method was performed against brute force attacks.

  3. Influence du traitement thermique sur quatre éléments métalliques ...

    African Journals Online (AJOL)

    Le but de notre étude est de suivre l\\'effet de la température de combustion sur quatre éléments métalliques (Cd, Cu, Pb et Zn). Les résultats expérimentaux montrent que la température de combustion a un effet sur la volatilisation des métaux lourds dans l'air. Pour déterminer le taux de vaporisation de ces métaux, des ...

  4. Characterization of surface antigen protein 1 (SurA1) from Acinetobacter baumannii and its role in virulence and fitness.

    Science.gov (United States)

    Liu, Dong; Liu, Zeng-Shan; Hu, Pan; Cai, Ling; Fu, Bao-Quan; Li, Yan-Song; Lu, Shi-Ying; Liu, Nan-Nan; Ma, Xiao-Long; Chi, Dan; Chang, Jiang; Shui, Yi-Ming; Li, Zhao-Hui; Ahmad, Waqas; Zhou, Yu; Ren, Hong-Lin

    2016-04-15

    Acinetobacter baumannii is a Gram-negative bacillus that causes nosocomial infections, such as bacteremia, pneumonia, and meningitis and urinary tract and wound infections. In the present study, the surface antigen protein 1 (SurA1) gene of A. baumannii strain CCGGD201101 was identified, cloned and expressed, and then its roles in fitness and virulence were investigated. Virulence was observed in the human lung cancer cell lines A549 and HEp-2 at one week after treatment with recombinant SurA1. One isogenic SurA1 knock-out strain, GR0015, which was derived from the A. baumannii strain CCGGD201101 isolated from diseased chicks in a previous study, highlighted the effect of SurA1 on fitness and growth. Its growth rate in LB broth and killing activity in human sera were significantly decreased compared with strain CCGGD201101. In the Galleria mellonella insect model, the isogenic SurA1 knock-out strain exhibited a lower survival rate and decreased dissemination. These results suggest that SurA1 plays an important role in the fitness and virulence of A. baumannii. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Spectral Imaging Technology-Based Evaluation of Radiation Treatment Planning to Remove Contrast Agent Artifacts.

    Science.gov (United States)

    Yi-Qun, Xu; Wei, Liu; Xin-Ye, Ni

    2016-10-01

    This study employs dual-source computed tomography single-spectrum imaging to evaluate the effects of contrast agent artifact removal and the computational accuracy of radiotherapy treatment planning improvement. The phantom, including the contrast agent, was used in all experiments. The amounts of iodine in the contrast agent were 30, 15, 7.5, and 0.75 g/100 mL. Two images with different energy values were scanned and captured using dual-source computed tomography (80 and 140 kV). To obtain a fused image, 2 groups of images were processed using single-energy spectrum imaging technology. The Pinnacle planning system was used to measure the computed tomography values of the contrast agent and the surrounding phantom tissue. The difference between radiotherapy treatment planning based on 80 kV, 140 kV, and energy spectrum image was analyzed. For the image with high iodine concentration, the quality of the energy spectrum-fused image was the highest, followed by that of the 140-kV image. That of the 80-kV image was the worst. The difference in the radiotherapy treatment results among the 3 models was significant. When the concentration of iodine was 30 g/100 mL and the distance from the contrast agent at the dose measurement point was 1 cm, the deviation values (P) were 5.95% and 2.20% when image treatment planning was based on 80 and 140 kV, respectively. When the concentration of iodine was 15 g/100 mL, deviation values (P) were -2.64% and -1.69%. Dual-source computed tomography single-energy spectral imaging technology can remove contrast agent artifacts to improve the calculated dose accuracy in radiotherapy treatment planning. © The Author(s) 2015.

  6. Influence du chlorpyriphos-ethyl sur quelques paramtres de ...

    African Journals Online (AJOL)

    admin

    testicules, les caractéristiques des spermatozoïdes épididymaires et sur les performances de reproduction ont été étudiés. .... par le test d'ANOVA et séparés par le test de. Duncan au ..... Dunnick JK, Gupta BN, Harris MW, Lamb. JC. 1984.

  7. Recensement des initiatives de la société civile axées sur le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    analyse sur la nature, la portée et l'ampleur des travaux réalisés, de même qu'à un répertoire commenté des organismes de la société civile travaillant sur des enjeux liés au développement au sein de la communauté musulmane de l'Inde.

  8. Pärt, Arvo: "Summa". Collage sur BACH. Fratres / Patric Wiklacz

    Index Scriptorium Estoniae

    Wiklacz, Patric

    1997-01-01

    Uuest heliplaadist "Pärt, Arvo: "Summa". Collage sur BACH. Fratres. Cantus in Memoriam Benjamin Britten. Summa. Festina Lente. Tabula rasa. Tapiola Sinfonietta / Jean-Jacques Kantorow". BIS-CD-834. 62:30 DDD

  9. Notes on basis band-pass circuits; Notes sur les circuits de base passe-bande

    Energy Technology Data Exchange (ETDEWEB)

    Ailloud, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-07-01

    Resistor load amplifier stages, basic band-pass RC networks, conventional single-tuned circuits, have the same transfer function. Common properties and differences because diverse magnitude of parameters with proposed problems are exposed. Next the case of several cascaded stages (or networks) is examined when there is no reaction ones to another. (author) [French] Les etages amplificateurs a resistances, les circuits passe-bande RC elementaires, le circuit resonnant classique possedent la meme fonction de transfert. On fait ressortir les proprietes communes et les differences de comportement dues aux ordres de grandeur qu'il est possible de donner aux parametres en fonction des problemes a resoudre. On examine ensuite le cas de plusieurs etages (ou de plusieurs circuits) en cascade lorsqu'ils ne reagissent pas les uns sur les autres. (auteur)

  10. Methodology for reliability allocation based on fault tree analysis and dualistic contrast

    Institute of Scientific and Technical Information of China (English)

    TONG Lili; CAO Xuewu

    2008-01-01

    Reliability allocation is a difficult multi-objective optimization problem.This paper presents a methodology for reliability allocation that can be applied to determine the reliability characteristics of reactor systems or subsystems.The dualistic contrast,known as one of the most powerful tools for optimization problems,is applied to the reliability allocation model of a typical system in this article.And the fault tree analysis,deemed to be one of the effective methods of reliability analysis,is also adopted.Thus a failure rate allocation model based on the fault tree analysis and dualistic contrast is achieved.An application on the emergency diesel generator in the nuclear power plant is given to illustrate the proposed method.

  11. Cosmetics Alter Biologically-Based Factors of Beauty: Evidence from Facial Contrast

    Directory of Open Access Journals (Sweden)

    Alex L. Jones

    2015-01-01

    Full Text Available The use of cosmetics by women seems to consistently increase their attractiveness. What factors of attractiveness do cosmetics alter to achieve this? Facial contrast is a known cue to sexual dimorphism and youth, and cosmetics exaggerate sexual dimorphisms in facial contrast. Here, we demonstrate that the luminance contrast pattern of the eyes and eyebrows is consistently sexually dimorphic across a large sample of faces, with females possessing lower brow contrasts than males, and greater eye contrast than males. Red-green and yellow-blue color contrasts were not found to differ consistently between the sexes. We also show that women use cosmetics not only to exaggerate sexual dimorphisms of brow and eye contrasts, but also to increase contrasts that decline with age. These findings refine the notion of facial contrast, and demonstrate how cosmetics can increase attractiveness by manipulating factors of beauty associated with facial contrast.

  12. Cosmetics alter biologically-based factors of beauty: evidence from facial contrast.

    Science.gov (United States)

    Jones, Alex L; Russell, Richard; Ward, Robert

    2015-02-28

    The use of cosmetics by women seems to consistently increase their attractiveness. What factors of attractiveness do cosmetics alter to achieve this? Facial contrast is a known cue to sexual dimorphism and youth, and cosmetics exaggerate sexual dimorphisms in facial contrast. Here, we demonstrate that the luminance contrast pattern of the eyes and eyebrows is consistently sexually dimorphic across a large sample of faces, with females possessing lower brow contrasts than males, and greater eye contrast than males. Red-green and yellow-blue color contrasts were not found to differ consistently between the sexes. We also show that women use cosmetics not only to exaggerate sexual dimorphisms of brow and eye contrasts, but also to increase contrasts that decline with age. These findings refine the notion of facial contrast, and demonstrate how cosmetics can increase attractiveness by manipulating factors of beauty associated with facial contrast.

  13. High Contrast Vacuum Nuller Testbed (VNT) Contrast, Performance and Null Control

    Science.gov (United States)

    Lyon, Richard G.; Clampin, Mark; Petrone, Peter; Mallik, Udayan; Madison, Timothy; Bolcar, Matthew R.

    2012-01-01

    Herein we report on our Visible Nulling Coronagraph high-contrast result of 109 contrast averaged over a focal planeregion extending from 14 D with the Vacuum Nuller Testbed (VNT) in a vibration isolated vacuum chamber. TheVNC is a hybrid interferometriccoronagraphic approach for exoplanet science. It operates with high Lyot stopefficiency for filled, segmented and sparse or diluted-aperture telescopes, thereby spanning the range of potential futureNASA flight telescopes. NASAGoddard Space Flight Center (GSFC) has a well-established effort to develop the VNCand its technologies, and has developed an incremental sequence of VNC testbeds to advance this approach and itsenabling technologies. These testbeds have enabled advancement of high-contrast, visible light, nulling interferometry tounprecedented levels. The VNC is based on a modified Mach-Zehnder nulling interferometer, with a W configurationto accommodate a hex-packed MEMS based deformable mirror, a coherent fiber bundle and achromatic phase shifters.We give an overview of the VNT and discuss the high-contrast laboratory results, the optical configuration, criticaltechnologies and null sensing and control.

  14. High contrast vacuum nuller testbed (VNT) contrast, performance, and null control

    Science.gov (United States)

    Lyon, Richard G.; Clampin, Mark; Petrone, Peter; Mallik, Udayan; Madison, Timothy; Bolcar, Matthew R.

    2012-09-01

    Herein we report on our Visible Nulling Coronagraph high-contrast result of 109 contrast averaged over a focal plane region extending from 1 - 4 λ/D with the Vacuum Nuller Testbed (VNT) in a vibration isolated vacuum chamber. The VNC is a hybrid interferometric/coronagraphic approach for exoplanet science. It operates with high Lyot stop efficiency for filled, segmented and sparse or diluted-aperture telescopes, thereby spanning the range of potential future NASA flight telescopes. NASA/Goddard Space Flight Center (GSFC) has a well-established effort to develop the VNC and its technologies, and has developed an incremental sequence of VNC testbeds to advance this approach and its enabling technologies. These testbeds have enabled advancement of high-contrast, visible light, nulling interferometry to unprecedented levels. The VNC is based on a modified Mach-Zehnder nulling interferometer, with a “W” configuration to accommodate a hex-packed MEMS based deformable mirror, a coherent fiber bundle and achromatic phase shifters. We give an overview of the VNT and discuss the high-contrast laboratory results, the optical configuration, critical technologies and null sensing and control.

  15. Effects of computed tomography contrast medium factors on contrast enhancement

    International Nuclear Information System (INIS)

    Terasawa, Kazuaki; Hatcho, Atsushi; Okuda, Itsuko

    2011-01-01

    The various nonionic iodinated contrast media used in contrast computed tomography (CT) studies differ in terms of their composition, characteristics, and iodine concentration (mgI/ml), as well as the volume injected (ml). Compared with ionic iodinated contrast media, nonionic iodinated contrast media are low-osmolar agents, with different agents having different osmotic pressures. Using a custom-made phantom incorporating a semipermeable membrane, the osmotic flow rate (hounsfield unit (HU)/s) could easily be measured based on the observed increase in CT numbers, and the relationship between the osmotic pressure and the osmotic flow rate could be obtained (r 2 =0.84). In addition, taking the effects of patient size into consideration, the levels of contrast enhancement in the abdominal aorta (AA) and inferior vena cava (IVC) were compared among four types of CT contrast medium. The results showed differences in contrast enhancement in the IVC during the equilibrium phase depending on the type of contrast medium used. It was found that the factors responsible for the differences observed in enhancement in the IVC were the osmotic flow rate and the volume of the blood flow pathways in the circulatory system. It is therefore considered that the reproducibility of contrast enhancement is likely to be reduced in the examination of parenchymal organs, in which scanning must be performed during the equilibrium phase, even if the amount of iodine injected per unit body weight (mgI/kg) is maintained at a specified level. (author)

  16. Advanced Contrast Agents for Multimodal Biomedical Imaging Based on Nanotechnology.

    Science.gov (United States)

    Calle, Daniel; Ballesteros, Paloma; Cerdán, Sebastián

    2018-01-01

    Clinical imaging modalities have reached a prominent role in medical diagnosis and patient management in the last decades. Different image methodologies as Positron Emission Tomography, Single Photon Emission Tomography, X-Rays, or Magnetic Resonance Imaging are in continuous evolution to satisfy the increasing demands of current medical diagnosis. Progress in these methodologies has been favored by the parallel development of increasingly more powerful contrast agents. These are molecules that enhance the intrinsic contrast of the images in the tissues where they accumulate, revealing noninvasively the presence of characteristic molecular targets or differential physiopathological microenvironments. The contrast agent field is currently moving to improve the performance of these molecules by incorporating the advantages that modern nanotechnology offers. These include, mainly, the possibilities to combine imaging and therapeutic capabilities over the same theranostic platform or improve the targeting efficiency in vivo by molecular engineering of the nanostructures. In this review, we provide an introduction to multimodal imaging methods in biomedicine, the sub-nanometric imaging agents previously used and the development of advanced multimodal and theranostic imaging agents based in nanotechnology. We conclude providing some illustrative examples from our own laboratories, including recent progress in theranostic formulations of magnetoliposomes containing ω-3 poly-unsaturated fatty acids to treat inflammatory diseases, or the use of stealth liposomes engineered with a pH-sensitive nanovalve to release their cargo specifically in the acidic extracellular pH microenvironment of tumors.

  17. IMPACT DU SECTEUR FINANCIER SUR L'ACTIVITE ...

    African Journals Online (AJOL)

    visant à adapter le secteur financier à l'économie de marché. Ces réformes ont pour objectif d'éliminer .... économiques (secteur privé et secteur public), deux comptes regroupant les institutions financières à savoir la .... Maroc.11 Nadia Bentaleb (2002)12 a étudié l'impact d'un investissement énergétique sur une économie ...

  18. Retour d'expérience sur la co-construction d'un guide sur la gouvernance territoriale

    OpenAIRE

    Maurel, P.; Barbe, E.; Rey-Valette, H.; Chia, E.; Soulard, C.; Michel, L.; Pinto, M.

    2014-01-01

    / La gouvernance territoriale est devenue un enjeu majeur et une question centrale pour la mise en oeuvre des politiques publiques. Dans le cadre du programme de recherche en partenariat PSDR, un collectif hybride composé de chercheurs, de professionnels du développement territorial et d'acteurs locaux s'est réuni au sein du projet Gouv.Innov. En s'appuyant sur plusieurs terrains d'étude, ce collectif a progressivement construit une définition de la gouvernance territoriale ainsi qu'une grill...

  19. A New Adaptive Gamma Correction Based Algorithm Using DWT-SVD for Non-Contrast CT Image Enhancement.

    Science.gov (United States)

    Kallel, Fathi; Ben Hamida, Ahmed

    2017-12-01

    The performances of medical image processing techniques, in particular CT scans, are usually affected by poor contrast quality introduced by some medical imaging devices. This suggests the use of contrast enhancement methods as a solution to adjust the intensity distribution of the dark image. In this paper, an advanced adaptive and simple algorithm for dark medical image enhancement is proposed. This approach is principally based on adaptive gamma correction using discrete wavelet transform with singular-value decomposition (DWT-SVD). In a first step, the technique decomposes the input medical image into four frequency sub-bands by using DWT and then estimates the singular-value matrix of the low-low (LL) sub-band image. In a second step, an enhanced LL component is generated using an adequate correction factor and inverse singular value decomposition (SVD). In a third step, for an additional improvement of LL component, obtained LL sub-band image from SVD enhancement stage is classified into two main classes (low contrast and moderate contrast classes) based on their statistical information and therefore processed using an adaptive dynamic gamma correction function. In fact, an adaptive gamma correction factor is calculated for each image according to its class. Finally, the obtained LL sub-band image undergoes inverse DWT together with the unprocessed low-high (LH), high-low (HL), and high-high (HH) sub-bands for enhanced image generation. Different types of non-contrast CT medical images are considered for performance evaluation of the proposed contrast enhancement algorithm based on adaptive gamma correction using DWT-SVD (DWT-SVD-AGC). Results show that our proposed algorithm performs better than other state-of-the-art techniques.

  20. Systèmes d'innovation propices à un développement axé sur l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Tant la Chine que l'Inde tentent actuellement de parvenir à un équilibre entre leur rapide croissance économique et technologique dans un contexte de mondialisation, d'une part, et l'équité sociale et la croissance économique durable, d'autre part. Ce projet portera sur deux innovations axées sur l'inclusion dans deux ...

  1. The safety and efficacy of hemostasis with Clo-Sur P.A.D. after transcatheter arterial chemoembolization

    International Nuclear Information System (INIS)

    Jung, Seung Chai; Jae, Hwan Jun; Kim, Sang Youn; Lee, Whal; Chung, Jin Wook; Park, Jae Hyung

    2007-01-01

    We wanted to evaluate the safety and efficacy of a new hemostatic device, Clo-Sur P.A.D., at an arterial access site after performing femoral arterial catheterization to achieve transcatheter arterial chemoembolization (TACE). From August 2002 to March 2005, 113 patients who underwent TACE and agreed on using the Clo-Sur P.A.D. were enrolled in this study. We evaluated the mean time interval from compression to the first movement and also to the first walk. We also evaluated such complications as rebleeding, pseudoaneurysm, vascular occlusion, hematoma, infection and pain. For 92 patients who had previous experiences with manual compression, we evaluated their preference of hemostatic method by asking them. Successful hemostasis was achieved with the Clo-Sur P.A.D. in 105 subjects (92%). The mean time interval from compression to the first movement was 201 minutes, and that to the first walk was 267 minutes. There was no statistical difference between the complicated and the uncomplicated groups for the mean time, prothrombin time, Child-Pugh class and platelet count (ρ > 0.05). Rebleeding occurred in 3 patients (2.7%) and mild hematoma around puncture site was noted in 5 patients (5.4%). Eighty-seven patients (95%) preferred Clo-Sur P.A.D. to the manual compression method. The Clo-Sur P.A.D. is a safe and effective hemostatic device and it provides early ambulation after TACE

  2. Prospective randomized study of contrast reaction management curricula: Computer-based interactive simulation versus high-fidelity hands-on simulation

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Carolyn L., E-mail: wangcl@uw.edu [Department of Radiology, University of Washington, Box 357115, 1959 NE Pacific Street, Seattle, WA 98195-7115 (United States); Schopp, Jennifer G.; Kani, Kimia [Department of Radiology, University of Washington, Box 357115, 1959 NE Pacific Street, Seattle, WA 98195-7115 (United States); Petscavage-Thomas, Jonelle M. [Penn State Hershey Medical Center, Department of Radiology, 500 University Drive, Hershey, PA 17033 (United States); Zaidi, Sadaf; Hippe, Dan S.; Paladin, Angelisa M.; Bush, William H. [Department of Radiology, University of Washington, Box 357115, 1959 NE Pacific Street, Seattle, WA 98195-7115 (United States)

    2013-12-01

    Purpose: We developed a computer-based interactive simulation program for teaching contrast reaction management to radiology trainees and compared its effectiveness to high-fidelity hands-on simulation training. Materials and methods: IRB approved HIPAA compliant prospective study of 44 radiology residents, fellows and faculty who were randomized into either the high-fidelity hands-on simulation group or computer-based simulation group. All participants took separate written tests prior to and immediately after their intervention. Four months later participants took a delayed written test and a hands-on high-fidelity severe contrast reaction scenario performance test graded on predefined critical actions. Results: There was no statistically significant difference between the computer and hands-on groups’ written pretest, immediate post-test, or delayed post-test scores (p > 0.6 for all). Both groups’ scores improved immediately following the intervention (p < 0.001). The delayed test scores 4 months later were still significantly higher than the pre-test scores (p ≤ 0.02). The computer group's performance was similar to the hands-on group on the severe contrast reaction simulation scenario test (p = 0.7). There were also no significant differences between the computer and hands-on groups in performance on the individual core competencies of contrast reaction management during the contrast reaction scenario. Conclusion: It is feasible to develop a computer-based interactive simulation program to teach contrast reaction management. Trainees that underwent computer-based simulation training scored similarly on written tests and on a hands-on high-fidelity severe contrast reaction scenario performance test as those trained with hands-on high-fidelity simulation.

  3. Prospective randomized study of contrast reaction management curricula: Computer-based interactive simulation versus high-fidelity hands-on simulation

    International Nuclear Information System (INIS)

    Wang, Carolyn L.; Schopp, Jennifer G.; Kani, Kimia; Petscavage-Thomas, Jonelle M.; Zaidi, Sadaf; Hippe, Dan S.; Paladin, Angelisa M.; Bush, William H.

    2013-01-01

    Purpose: We developed a computer-based interactive simulation program for teaching contrast reaction management to radiology trainees and compared its effectiveness to high-fidelity hands-on simulation training. Materials and methods: IRB approved HIPAA compliant prospective study of 44 radiology residents, fellows and faculty who were randomized into either the high-fidelity hands-on simulation group or computer-based simulation group. All participants took separate written tests prior to and immediately after their intervention. Four months later participants took a delayed written test and a hands-on high-fidelity severe contrast reaction scenario performance test graded on predefined critical actions. Results: There was no statistically significant difference between the computer and hands-on groups’ written pretest, immediate post-test, or delayed post-test scores (p > 0.6 for all). Both groups’ scores improved immediately following the intervention (p < 0.001). The delayed test scores 4 months later were still significantly higher than the pre-test scores (p ≤ 0.02). The computer group's performance was similar to the hands-on group on the severe contrast reaction simulation scenario test (p = 0.7). There were also no significant differences between the computer and hands-on groups in performance on the individual core competencies of contrast reaction management during the contrast reaction scenario. Conclusion: It is feasible to develop a computer-based interactive simulation program to teach contrast reaction management. Trainees that underwent computer-based simulation training scored similarly on written tests and on a hands-on high-fidelity severe contrast reaction scenario performance test as those trained with hands-on high-fidelity simulation

  4. DECISIONS ET COMPETITIVITE SUR LE MARCHE UNIQUE EUROPEEN

    Directory of Open Access Journals (Sweden)

    Sirghi Nicoleta

    2008-05-01

    Full Text Available L’un des traits importants du marché unique européen, a comme source le męme énoncé du principal objectif de l’intégration européenne ainsi que: l’harmonisation des niveaux du développement des Etats Membres et l’augmentation du niveau de vie dans l’ensemble de la communauté. Pour le marché unique européen, cet aspect se traduit par une permanente et soutenue augmentation de la demande. Cet ouvrage présente au début une analyse des éléments spécifiques du marché européen. Ensuite on identifie les opportunités et les risques au niveau macroéconomique adjointes aux perspectives du marché unique européen. Comme fondement on présente des stratégies du développement réalisables au niveau microéconomique que puissent assurer l’augmentation du niveau sur la compétitivité des sociétés sur le marché unique européen.

  5. New K-Ar ages of altered rocks from Paramillos Sur and Norte: Interpretation of the results; Nuevas edades K-Ar de las rocas alteradas de Paramillos Sur y Norte: Interpretacion de los resultados

    Energy Technology Data Exchange (ETDEWEB)

    Koukharsky, Magdalena; Brodtkorb, Alejo [Buenos Aires Univ. (Argentina). Facultad de Ciencias Exactas y Naturales; Munizaga, Francisco [Chile Univ., Santiago (Chile). Dept. de Geologia

    1998-07-01

    The whole-rock K-Ar dates from porphyry copper prospects of Paramillos Sur (phyllic and potasic alteration zones) and Paramillos Norte (propilitic zone) are reported. Radiometric data yielded 17,8 {+-} 0,9 Ma, 15,8 {+-} 1,0 Ma and 15,2 {+-} 0,5 Ma in Paramillos Sur, and 17,3 {+-} 0,7 Ma in Paramillos Norte, which can be added to an previously reported age of 16,4 {+-} 0,3 Ma. These data are in agreement with isotopic ages from non altered or non mineralized magmatic rocks of the region. When the isotopic ages and petrographic characteristics of the dated rocks are considered, two alteration-mineralization events are suggested for Paramillos Sur prospect. However this possibility needs to be confirmed by means of future studies, in view of the reduced interval between these events when compared with the analytical errors. (author)

  6. Plan for mass accelerator spectrometry at Gif-sur-Yvette and Saclay

    International Nuclear Information System (INIS)

    Berthier, B.; Bianchi, L.; Delibrias, G.; Koechlin, Y.

    1981-05-01

    From early 50', a carbon 14 dating laboratory was created at the Centre des Faibles Radioactivites de Gif-sur-Yvette (C.F.R.). From this time, more than 5,000 archaeological and geological samples were measured with the Libby method by this laboratory. C.F.R. is in the way to actualize its dating activities with the new accelerator method. A 3 MV General Ionex Tandetron is planed to be located at Gif-sur-Yvette next year and shared with Orsay University for 14 C. 10 Be and 36 Cl mass spectroscopy measurement. During the same time attempts have been made to adapt the Super FN Tandem of the Centre d'Etudes Nucleaires de Saclay for 14 C dating

  7. La croissance demographique et son impact sur le developpement ...

    African Journals Online (AJOL)

    La croissance demographique et son impact sur le developpement des grandes villes au ... La ville de Porto-Novo au Bénin n'est pas en marge de cette réalité que ... and the need for improving its framework of life through its development.

  8. L'impact de Quizlet sur la dynamique motivationnelle des élèves lors de l'apprentissage du vocabulaire allemand

    OpenAIRE

    André, Joanne; Berrio, Lucas; Pellet, Jean-Philippe

    2017-01-01

    Pour ce travail, nous nous sommes intéressés à l'effet que pouvait avoir les TIC sur la motivation des élèves. Nous nous sommes penchés sur la plate-forme web Quizlet qui propose différents outils pour réviser un contenu préalablement défini par l'enseignant. Ainsi, nous avons dirigé notre recherche sur l'impact de Quizlet sur la dynamique motivationnelle des élèves dans le cadre de l'apprentissage du vocabulaire allemand. Nous comparons cette méthode d'apprentissage avec les méthodes dites t...

  9. Benchtop phase-contrast X-ray imaging

    Energy Technology Data Exchange (ETDEWEB)

    Gundogdu, O. [Department of Physics, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom)], E-mail: o.gundogdu@surrey.ac.uk; Nirgianaki, E.; Che Ismail, E.; Jenneson, P.M.; Bradley, D.A. [Department of Physics, University of Surrey, Guildford, Surrey GU2 7XH (United Kingdom)

    2007-12-15

    Clinical radiography has traditionally been based on contrast obtained from absorption when X-rays pass through the body. The contrast obtained from traditional radiography can be rather poor, particularly when it comes to soft tissue. A wide range of media of interest in materials science, biology and medicine exhibit very weak absorption contrast, but they nevertheless produce significant phase shifts with X-rays. The use of phase information for imaging purposes is therefore an attractive prospect. Some of the X-ray phase-contrast imaging methods require highly monochromatic plane wave radiation and sophisticated X-ray optics. However, the propagation-based phase-contrast imaging method adapted in this paper is a relatively simple method to implement, essentially requiring only a microfocal X-ray tube and electronic detection. In this paper, we present imaging results obtained from two different benchtop X-ray sources employing the free space propagation method. X-ray phase-contrast imaging provides higher contrast in many samples, including biological tissues that have negligible absorption contrast.

  10. Saint-André-des-Eaux (Côtes-d’Armor : nouveaux éléments sur l’église et sur ses décors peints

    Directory of Open Access Journals (Sweden)

    Mathias Dupuis

    2009-09-01

    Full Text Available Nous avions déjà présenté dans le précédent numéro du Bulletin du Centre d'études médiévales d’Auxerre les premières recherches sur l’ancienne église paroissiale de Saint-André-des-Eaux . La réalisation de sondages en juin 2008 ainsi qu’une dernière série d’observations sur le bâti, préalables à la consolidation des murs de l’église et des vestiges de peintures murales, permettent désormais de mieux cerner l’histoire monumentale de cet édifice et de ses décors peints.Quatre sondages ont été o...

  11. Études de cas portant sur la recherche, les partenariats et l'équité en ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    16 juil. 2012 ... Martin Forde, Karen Morrison, Eric Dewailly, Neela Badrie, Lyndon Robertson. Collaboration en matière de recherche sur la lutte contre les infections et la santé au travail sur trois continents : Une réussite de portée internationale. Annalee Yassi, Elizabeth A. Bryce, Jaime Breihl, Marie-Claude Lavoie, ...

  12. Influence des actions anthropiques sur la dynamique spatio ...

    African Journals Online (AJOL)

    Sci-Nat

    Située à proximité de Kinshasa, la province du Bas-Congo (R.D. Congo) est l'une des principales pourvoyeuses en produits vivriers de cette ville. Par conséquent, l'augmentation de la pression sur les ressources naturelles s'accentue. L'analyse diachronique du paysage peut servir à montrer l'effet des actions ...

  13. Modèle d’alerte des crises bancaires basé sur une approche hybride : modèle bayésien – machines à vecteurs supports

    Directory of Open Access Journals (Sweden)

    Taha Zaghdoudi

    2016-09-01

    Full Text Available Ces dernières années, la succession des crises bancaires, qui dans la plupart ont été soldées par des pertes économiques et financières énormes, a suscité l’intérêt de plusieurs chercheurs. Empiriquement, ces auteurs ont opté pour des modèles d’alerte précoce (Early Warning System pour prévenir leurs occurrences. L’objectif de ce papier est de construire un Modèle d’alerte des crises bancaires basé sur une approche hybride. Sur la base des données relatives à 22 pays qui ont subi des crises bancaires observées sur la période 1990–2011, nous avons développé un modèle d’alerte des crises bancaires. Ce modèle est basé sur une approche hybride Bayesian model averaging–Support vectors machine. Sur les 25 variables explicatives retenues, les résultats empiriques du modèle hybride ont fait ressortir 9 indicateurs qui sont considérés comme les principaux facteurs déterminants du déclenchement des crises bancaires. Ces derniers ont une probabilité postérieure d’inclusion supérieure à 0,5. Ces indicateurs potentiels sont la rentabilité nette des actifs, la compétitivité de l’intermédiation bancaire, les provisions sur les créances douteuses, les investissements directs étrangers, la concentration bancaire, la stabilité financière des banques, les produits nets financiers, le taux d’intérêt réel et le taux d’inflation.

  14. Measurements and simulations analysing the noise behaviour of grating-based X-ray phase-contrast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Weber, T., E-mail: thomas.weber@physik.uni-erlangen.de [University of Erlangen-Nuremberg, ECAP - Erlangen Center for Astroparticle Physics, Erwin-Rommel-Str. 1, 91058 Erlangen (Germany); Bartl, P.; Durst, J. [University of Erlangen-Nuremberg, ECAP - Erlangen Center for Astroparticle Physics, Erwin-Rommel-Str. 1, 91058 Erlangen (Germany); Haas, W. [University of Erlangen-Nuremberg, ECAP - Erlangen Center for Astroparticle Physics, Erwin-Rommel-Str. 1, 91058 Erlangen (Germany); University of Erlangen-Nuremberg, Pattern Recognition Lab, Martensstr. 3, 91058 Erlangen (Germany); Michel, T.; Ritter, A.; Anton, G. [University of Erlangen-Nuremberg, ECAP - Erlangen Center for Astroparticle Physics, Erwin-Rommel-Str. 1, 91058 Erlangen (Germany)

    2011-08-21

    In the last decades, phase-contrast imaging using a Talbot-Lau grating interferometer is possible even with a low-brilliance X-ray source. With the potential of increasing the soft-tissue contrast, this method is on its way into medical imaging. For this purpose, the knowledge of the underlying physics of this technique is necessary. With this paper, we would like to contribute to the understanding of grating-based phase-contrast imaging by presenting results on measurements and simulations regarding the noise behaviour of the differential phases. These measurements were done using a microfocus X-ray tube with a hybrid, photon-counting, semiconductor Medipix2 detector. The additional simulations were performed by our in-house developed phase-contrast simulation tool 'SPHINX', combining both wave and particle contributions of the simulated photons. The results obtained by both of these methods show the same behaviour. Increasing the number of photons leads to a linear decrease of the standard deviation of the phase. The number of used phase steps has no influence on the standard deviation, if the total number of photons is held constant. Furthermore, the probability density function (pdf) of the reconstructed differential phases was analysed. It turned out that the so-called von Mises distribution is the physically correct pdf, which was also confirmed by measurements. This information advances the understanding of grating-based phase-contrast imaging and can be used to improve image quality.

  15. Low contrast detectability and spatial resolution with model-based iterative reconstructions of MDCT images: a phantom and cadaveric study

    Energy Technology Data Exchange (ETDEWEB)

    Millon, Domitille; Coche, Emmanuel E. [Universite Catholique de Louvain, Department of Radiology and Medical Imaging, Cliniques Universitaires Saint Luc, Brussels (Belgium); Vlassenbroek, Alain [Philips Healthcare, Brussels (Belgium); Maanen, Aline G. van; Cambier, Samantha E. [Universite Catholique de Louvain, Statistics Unit, King Albert II Cancer Institute, Brussels (Belgium)

    2017-03-15

    To compare image quality [low contrast (LC) detectability, noise, contrast-to-noise (CNR) and spatial resolution (SR)] of MDCT images reconstructed with an iterative reconstruction (IR) algorithm and a filtered back projection (FBP) algorithm. The experimental study was performed on a 256-slice MDCT. LC detectability, noise, CNR and SR were measured on a Catphan phantom scanned with decreasing doses (48.8 down to 0.7 mGy) and parameters typical of a chest CT examination. Images were reconstructed with FBP and a model-based IR algorithm. Additionally, human chest cadavers were scanned and reconstructed using the same technical parameters. Images were analyzed to illustrate the phantom results. LC detectability and noise were statistically significantly different between the techniques, supporting model-based IR algorithm (p < 0.0001). At low doses, the noise in FBP images only enabled SR measurements of high contrast objects. The superior CNR of model-based IR algorithm enabled lower dose measurements, which showed that SR was dose and contrast dependent. Cadaver images reconstructed with model-based IR illustrated that visibility and delineation of anatomical structure edges could be deteriorated at low doses. Model-based IR improved LC detectability and enabled dose reduction. At low dose, SR became dose and contrast dependent. (orig.)

  16. Jouer pour apprendre : est-ce bien sérieux ? Réflexions théoriques sur les relations entre jeu (vidéo et apprentissage

    Directory of Open Access Journals (Sweden)

    Vincent Berry

    2011-05-01

    Full Text Available Cet article propose une réflexion théorique sur les relations entre jeu (vidéo et éducation. A partir d’une revue de la littérature et sur la base d’une recherche consacrée à l’étude des joueurs de « jeux de rôles en ligne massivement multijoueurs », ce texte met en avant la complexité dans les sciences de l’éducation à penser le jeu comme espace d’apprentissage et propose quelques éléments théoriques pour aborder cette problématique.

  17. Oradour-sur-Glane: On the emergence of a glocal site of memory in France

    Directory of Open Access Journals (Sweden)

    Léger, Eva

    2014-12-01

    Full Text Available Oradour-sur-Glane (France is the memorial site of a massacre perpetrated by the Second SS Panzer Division Das Reich on June 10th, 1944. It preserves the memory of the 642 people slaughtered there, including 18 Spanish refugees. In 1945, the French State, led by General de Gaulle, decided to preserve the ruins of Oradour-sur- Glane. Since then, a series of commemorative processes have ensued at the site, corresponding to different temporalities. Over time, this site of national memory has been linked both with European memory discourse and with the private memory of exiled Spaniards and, consequently, with the memory of the Spanish Civil War and Francoism. In this article, I analyze the different appropriations and interpretations of the site, focusing in particular on the memory of the exiles. To do so, I will look into the initiatives undertaken between 2008 and 2014, considering both the institutions and the associations related to Oradour-sur-Glane.Oradour-sur-Glane (Francia es el lugar de memoria de una masacre perpetrada por la segunda división blindada S.S. Das Reich el 10 de junio de 1944 que conserva el recuerdo de sus 642 supliciados, entre los cuales 18 españoles refugiados. En 1945, el Estado francés encabezado por el General de Gaulle decidió preservar las ruinas de Oradour-sur-Glane. Desde entonces, diferentes procesos conmemorativos, correspondientes a temporalidades destacadas, se han sucedido en el sitio. Con el tiempo, este lugar de memoria nacional, se ha vinculado tanto con un discurso de memoria europeo como con la memoria particular de los españoles exiliados y a través de ello con la memoria de la Guerra Civil española y del franquismo. En este estudio analizaré las diferentes apropiaciones e interpretaciones de este lugar, enfocándome especialmente en la memoria de los exiliados. Para esto, contemplaré las iniciativas que se han desarrollado entre los años 2008 y 2014, atendiendo tanto a las instituciones como a

  18. Evaluation in vitro de l'efficacité du fipronil sur Culex pipiens pipiens

    OpenAIRE

    Toral y Caro, Muriel

    2005-01-01

    Les moustiques sont responsables de nuisances directes et indirectes, chez l'homme et chez l'animal. C'est pourquoi il est intéressant de tester l'efficacité de nouvelles molécules sur ces insectes. Ce travail expérimental vise à tester l'efficacité potentielle du fipronil sur les moustiques appartenant au complexe Culex pipiens au moyen d'un nouveau test mis en place au laboratoire. Une première partie de ce travail est consacrée à l'étude bibliographique des caractéristiques de Culex ...

  19. Entretien sur la psychanalyse: réflexions en marge

    Directory of Open Access Journals (Sweden)

    Giuseppe Martini

    2016-08-01

    Full Text Available L’auteur propose ici un commentaire sur les points les plus importants de son entretien de février 2003 avec Paul Ricœur consacré aux rapports entre herméneutique et psychanalyse. Bien que le philosophe se situe dans une réelle continuité par rapport à sa contribution de 1965, il enrichit toutefois sa réflexion philosophique sur la psychanalyse en proposant plusieurs innovations, en ce qui concerne plus particulièrement les thèmes du récit, du soi et de l’éthique. Dans les conclusions de son commentaire, l’auteur souligne l’importance des concepts d’“irreprésentable” et d’“intraduisible”: non seulement, en effet, ces concepts sont dans la ligne de nombreuses contributions de la psychanalyse contemporaine, mais la profondeur de la réflexion ricœurienne augmente en outre leur potentiel théorique et même clinique.

  20. Resist-based measurement of contrast transfer function in a 0.3-NA microfield optic

    International Nuclear Information System (INIS)

    Cain, Jason P.; Naulleau, Patrick; Spanos, Costas J.

    2005-01-01

    Although extreme ultraviolet (EUV) lithography offers the possibility of very high-resolution patterning, the projection optics must be of extremely high quality in order to meet this potential. One key metric of the projection optic quality is the contrast transfer function (CTF), which is a measure of the aerial image contrast as a function of pitch. A static microfield exposure tool based on the 0.3-NA MET optic and operating at a wavelength of 13.5 nm has been installed at the Advanced Light Source, a synchrotron facility at the Lawrence Berkeley National Laboratory. This tool provides a platform for a wide variety of research into EUV lithography. In this work we present resist-based measurements of the contrast transfer function for the MET optic. These measurements are based upon line/space patterns printed in several different EUV photoresists. The experimental results are compared with the CTF in aerial-image simulations using the aberrations measured in the projection optic using interferometry. In addition, the CTF measurements are conducted for both bright-field and dark-field mask patterns. Finally, the orientation dependence of the CTF is measured in order to evaluate the effect of non-rotationally symmetric lens aberrations. These measurements provide valuable information in interpreting the results of other experiments performed using the MET and similar systems

  1. Electrolytic nickel deposits upon uranium; Depot electrolytique de nickel sur l'uraniun

    Energy Technology Data Exchange (ETDEWEB)

    Baudin, G; Chauvin, G; Coriou, H; Hure, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The authors present a new possibility to protect uranium by very adherent nickel deposits got by aqueous medium electrolysis. Surface treatment of uranium is based upon the chemical etching method from Lietazke. After thermal treatments at 600, 700 and 800 deg. C, under vacuum, a good intermetallic U-Ni diffusion is observed for each case. (author) [French] Les auteurs mettent en evidence une possibilite nouvelle de protection de l'uranium par des depots tres adherents de nickel realises par electrolyse en milieu aqueux. La preparation de surface de l'uranium est basee sur la methode du decapage chimique de Lietazke. Apres des traitements thermiques a 600, 700 et 800 deg. C, sous vide, on constate dans tous les cas une bonne diffusion intermetallique U-Ni. (auteur)

  2. Contrast Media: Are There Differences in Nephrotoxicity among Contrast Media?

    Science.gov (United States)

    2014-01-01

    Iodinated contrast agents are usually classified based upon their osmolality—high, low, and isosmolar. Iodinated contrast agents are also nephrotoxic in some but not all patients resulting in loss of glomerular filtration rate. Over the past 30 years, nephrotoxicity has been linked to osmolality although the precise mechanism underlying such a link has been elusive. Improvements in our understanding of the pathogenesis of nephrotoxicity and prospective randomized clinical trials have attempted to further explore the relationship between osmolality and nephrotoxicity. In this review, the basis for our current understanding that there are little if any differences in nephrotoxic potential between low and isosmolar contrast media will be detailed using data from clinical studies. PMID:24587997

  3. Descriptions énonciative, informationnelle et argumentative : aspects discursifs sur quelques cas de figure

    Directory of Open Access Journals (Sweden)

    Forsgren Mats

    2012-07-01

    Full Text Available Les recherches sur l’énonciation, en l’occurrence celles appartenant au courant Ducrot, à l’école dit de Genève comme à l’école dite scandinave (portant le sigle « Scapoline », pour n’en mentionner que quelques-unes, donnent depuis quelques décennies de remarquables résultats portant sur la dimension polyphonique et argumentative du langage, sur le jeu discursif des points de vue et des êtres discursifs, de la prise en charge énonciative et du statut assertif (assertion/présupposition/supposition, comme sur le fonctionnement des différents types de marqueurs dits « discursifs ». La contribution de Henning Nølke, donnée lors du CMLF organisé en 2008 à Paris, brosse brillamment l’historique et l’élaboration ultérieure de ce courant. Nul doute que les résultats de bon nombre de ces recherches appartiendront dorénavant aux acquis descriptifs de notre science, qu’il s’agisse du discours rapporté, de la négation, des marqueurs de par exemple la concession ou la causalité. Cependant, il me semble que cette théorisation énonciative, pour heuristiquement valable qu’elle soit – ce qui est indéniable– rencontre parfois des problèmes lorsqu’elle est confrontée avec d’autres dimensions de la description du sens discursif, et testée dans «... le patient travail de confrontation minutieuse des outils avec le réel (en l’occurrence les textes dont ils sont censés rendre compte » (Alain Rabatel, 2010 : 109. C’est pourquoi dans cette communication j’aimerais discuter, à partir d’une enquête portant sur la distribution des marqueurs causaux dans plusieurs genres discursifs, deux problèmes de l’approche énonciative : sa rencontre avec la structure dite informationnelle et la prise en charge énonciative dans un cas bien précis, notamment certaines structures appositives.

  4. La cobertura televisiva del fútbol en el Sur de Brasil y de España: RBS – Canal Sur

    Directory of Open Access Journals (Sweden)

    Joaquín M. Marín Montín

    2002-01-01

    Full Text Available Este artículo constituye parte de un trabajo comparativo entre Brasil y España, correspondiente al tratamiento que los medios de comunicación hacen del deporte. En él se analizan las claves que configuran el acercamiento a un mismo fenómeno sociológico, como es el fútbol, en dos realidades culturales diferentes. La programación deportiva de televisión llevada a cabo por Canal Sur en Andalucía y RBS en Rio Grande do Sul, así como la cobertura que ambas cadenas realizan en sus retransmisiones en directo del fútbol completan el análisis del presente estudio.ABSTRACTThis article is part of a comparative research between Brazil and Spain, about how the media treats the sports activities. Besides, this study analyses the keys of the same sociological phenomenon, which is football, in two different cultural realities. The broadcasting on television regarding sports events in Andalusia with Canal Sur, and Rio Grande do Sul with RBS. The live broadcasting of these channels completes the analysis of the present research.

  5. An albumin-based gold nanocomposites as potential dual mode CT/MRI contrast agent

    Science.gov (United States)

    Zhao, Wenjing; Chen, Lina; Wang, Zhiming; Huang, Yuankui; Jia, Nengqin

    2018-02-01

    In pursuit of the biological detection applications, recent years have witnessed the prosperity of novel multi-modal nanoprobes. In this study, biocompatible bovine serum albumin (BSA)-coated gold nanoparticles (Au NPs) containing Gd (III) as the contrast agent for both X-ray CT and T1-weighted MR imaging is reported. Firstly, the Au NPs with BSA coating (Au@BSA) was prepared through a moderate one-pot reduction route in the presence of hydrazine hydrate as reducer. Sequentially, the BSA coating enables modification of diethylenetriaminepentaacetic acid (DTPA) as well as targeting reagent hyaluronic acid (HA), and further chelation of Gd (III) ions led to the formation of biomimetic nanoagent HA-targeted Gd-Au NPs (HA-targeted Au@BSA-Gd-DTPA). Several techniques were used to thoroughly characterize the formed HA-targeted Gd-Au NPs. As expected, the as-prepared nanoagent with mean diameter of 13.82 nm exhibits not only good colloid stablility and water dispersibility, but also satisfying low cytotoxicity and hemocompatibility in the tested concentration range. Additionally, for the CT phantoms, the obtained nanocomplex shows an improved contrast in CT scanning than that of Au@BSA as well as small molecule iodine-based CT contrast agents such as iopromide. Meanwhile, for the T1-weighted MRI images, there is a linear increase of contrast with concentration of Gd for the two cases of HA-targeted Gd-Au NPs and Magnevist. Strikingly, the nanoagent we explored displays a relatively higher r1 relaxivity than that of commercial MR contrast agents. Therefore, this newly constructed nanoagent could be used as contrast agents for synergistically enhanced X-ray CT and MR phantoms, holding promising potential for future biomedical applications.

  6. Analyse des erreurs dans les calculs sur ordinateurs Error Analysis in Computing

    Directory of Open Access Journals (Sweden)

    Vignes J.

    2006-11-01

    Full Text Available La méthode présentée ici permet d'évaluer l'erreur sur les résultats d'algorithmes, erreurs dues à l'arithmétique à précision limitée de la machines L'idée de base de cette méthode est qu'à un algorithme donné fournissant un résultat algébrique unique r, correspond en informatique un ensemble R de résultats numériques qui sont tous représentatifs de résultat exact r. La méthode de permutation-perturbation que nous présentons ici permet d'obtenir les éléments de R. La perturbation agit sur les données et résultats de chaque opération élémentaire. La permutation agit sur l'ordre d'exécution des opérations. Une étude statistique des éléments de R permet d'estimer l'erreur commise. Dans la pratique, il suffit de 2 ou 3 éléments de R pour connaître cette erreur. This paper describes a new method for evaluating the error in the results of computation of an algorithm. The basic idea underlying the method is that while in algebra a given algorithm provides a single result r, this same algorithm carried out on a computer provides a set R of numerical results that are ail representative of the exact algebraic result r. The permutation-perturbation method described here can be used to obtain the elements of R. The perturbation acts on the data and results of each elementary operation, and the permutation acts on the order in which operations are carried out. A statistical analysis of the elements of R is performed to determine the error committed. In practice, 2 to 4 R elements are sufficient for determining the error.

  7. Compétences, gouvernance et nanotechnologies : pleins feux sur l ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... pour prendre part au débat et relever les défis que posent les nanotechnologies. En plus ... de son Dialogue mondial sur la nanotechnologie et les populations pauvres (Global ... Multi level governance (MLG) framework for nanotechnology.

  8. Note sur l'environnement hydro-sédimentaire lagunaire Marcory ...

    African Journals Online (AJOL)

    Note sur l'environnement hydro-sédimentaire lagunaire Marcory-Riviera en lagune Ebrié en Côte d'Ivoire : Note on hydrology and sedimentary characteristics of the Marcory-Riviera lagoon area in Abidjan, Côte d'Ivoire.

  9. Optical spatial differentiator based on subwavelength high-contrast gratings

    Science.gov (United States)

    Dong, Zhewei; Si, Jiangnan; Yu, Xuanyi; Deng, Xiaoxu

    2018-04-01

    An optical spatial differentiator based on subwavelength high-contrast gratings (HCGs) is proposed experimentally. The spatial differentiation property of the subwavelength HCG is analyzed by calculating its spatial spectral transfer function based on the periodic waveguide theory. By employing the FDTD solutions, the performance of the subwavelength HCG spatial differentiator was investigated numerically. The subwavelength HCG differentiator with the thickness at the nanoscale was fabricated on the quartz substrate by electron beam lithography and Bosch deep silicon etching. Observed under an optical microscope with a CCD camera, the spatial differentiation of the incident field profile was obtained by the subwavelength HCG differentiator in transmission without Fourier lens. By projecting the images of slits, letter "X," and a cross on the subwavelength HCG differentiator, edge detections of images were obtained in transmission. With the nanoscale HCG structure and simple optical implementation, the proposed optical spatial differentiator provides the prospects for applications in optical computing systems and parallel data processing.

  10. L’éthique du débat sur la fuite des cerveaux

    OpenAIRE

    Dumitru, Speranta

    2012-01-01

    Cet article analyse les engagements éthiques qui pèsent sur la méthodologie des recherches sur « la fuite des cerveaux » et qui conduisent les participants au débat public à remettre en cause le droit fondamental d’émigrer pour les personnes qualifiées. Nous identifions cinq présupposés de ce débat : au conséquentialisme, au prioritarisme et au nationalisme, nous ajoutons les biais que nous appelons « sédentaristes » et élitistes. Cette analyse nous permettra de montrer que même si l’émigrati...

  11. Niels Stensen (Nicolas Sténon, Discours sur l’anatomie du cerveau

    Directory of Open Access Journals (Sweden)

    Claire Crignon-De Oliveira

    2011-12-01

    Full Text Available Peut-on faire du cerveau, cet « organe de l’âme », un objet scientifique et philosophique ? À l’heure où les certitudes ont peut-être remplacé les doutes et le questionnement sur la légitimité et les conditions rendant possible la poursuite d’un tel objectif, la lecture du Discours de Sténon sur l’anatomie du cerveau semble s’imposer. L’aveu d’ignorance de l’auteur qui ouvre le texte est à la fois déconcertant et extrêmement rassurant. Loin de promettre aux lecteurs d’être en mesure de « cont...

  12. Soutien institutionnel à des organismes de recherche sur les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Asie du Sud (le Bangladesh, l'Inde, le Népal, le Pakistan et le Sri Lanka). Parmi les 16 demandeurs d'Asie du Sud retenus, neuf viennent de l'Inde. La recherche sur les politiques en Asie du Sud s'effectue principalement en Inde, forte d'une ...

  13. Étude sur l'escalade de la violence faite aux femmes en Amérique ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude sur l'escalade de la violence faite aux femmes en Amérique centrale. 21 juin 2016. Ana Carcedo. En Amérique centrale, on assiste à une escalade de la violence faite aux femmes et du nombre de meurtres de femmes (ou femicides). Or, il y a des lacunes sur le plan du signalement. Primo, malgré les efforts déployés ...

  14. Objective task-based assessment of low-contrast detectability in iterative reconstruction

    International Nuclear Information System (INIS)

    Racine, Damien; Ott, Julien G.; Ba, Alexandre; Ryckx, Nick; Bochud, Francois O.; Verdun, Francis R.

    2016-01-01

    Evaluating image quality by using receiver operating characteristic studies is time consuming and difficult to implement. This work assesses a new iterative algorithm using a channelised Hotelling observer (CHO). For this purpose, an anthropomorphic abdomen phantom with spheres of various sizes and contrasts was scanned at 3 volume computed tomography dose index (CTDI vol ) levels on a GE Revolution CT. Images were reconstructed using the iterative reconstruction method adaptive statistical iterative reconstruction-V (ASIR-V) at ASIR-V 0, 50 and 70 % and assessed by applying a CHO with dense difference of Gaussian and internal noise. Both CHO and human observers (HO) were compared based on a four-alternative forced-choice experiment, using the percentage correct as a figure of merit. The results showed accordance between CHO and HO. Moreover, an improvement in the low-contrast detection was observed when switching from ASIR-V 0 to 50 %. The results underpin the finding that ASIR-V allows dose reduction. (authors)

  15. Oligocene cetaceans from Baja California Sur, Mexico

    OpenAIRE

    Hernández Cisneros, Atzcalli Ehécatl; González Barba, Gerardo; Fordyce, Robert Ewan

    2017-01-01

    Abstract Baja California Sur has an important Cenozoic marine fossil record which includes diverse but poorly known Oligocene cetaceans from Mexico. Here we review the cetacean fossil record including new observations from materials that elucidate the evolution of the Neoceti in the Pacific basin. Fossils were collected from outcrops of the El Cien Formation (Oligocene-Early Miocene) and from San Gregorio Formation (Late Oligocene). The specimens belong to the paleontological collection of Mu...

  16. Late adverse reactions to intravascular iodine based contrast media

    DEFF Research Database (Denmark)

    Bellin, Marie-France; Stacul, Fulvio; Webb, Judith A W

    2011-01-01

    DEFINITION: Late adverse reactions (LAR) to contrast media (CM) are defined as reactions occurring 1 h to 1 week after exposure. NEED FOR REVIEW: In view of more prospective studies of LAR and new data about their pathophysiology, the Contrast Medium Safety Committee (CMSC) of the European Societ...

  17. Rapport. Sur le droit à l’appréciation critique et sur les restrictions légitimes de l’importunité de l'homosexualité

    Directory of Open Access Journals (Sweden)

    Mikhaïl N. Kouznetsov

    2011-10-01

    Full Text Available Dans le présent Rapport on entend par la notion “homosexualité” sa plus large et spécifique signification en tant que “l’ideologie de l'homosexualisme”. SOMMAIRE: Introduction - 1. Argumentation du droit à l’évaluation critique de l'homosexualité et de ses aspects sociaux - 2. Caractère agressif de l'idéologie de l'homosexualisme - 3. Atteinte cruelle et inhumaine de lésions corporelles portée à l’individu, les dommages à sa santé dans la pratique de l'homosexualité ”masculine” - 4. Sur la manipulation par les chiffres - 5.  Mythe sur la discriminations massives des homosexuels - 6. Violation des Droits de l’Homme et insulte à la dignité humaine pendant les ”gay parades” - 7. Normes de la législation étrangère, émanant de la reconnaissance par l'État des méfaits sociaux de l'homosexualité - 8. Positions juridiques de la Cour Européenne des Droits de l'Homme ayant le point d’impact sur l’élaboration des solutions à propos des questions à discuter - 9. Contradiction à ”l’Ordre public” de la Fédération de Russie des exigences d'établir des régimes juridiques privilégiés pour les homosexuels et leurs groupements et de poursuivre pour toute critique de l'homosexualité – 10. Conclusions.

  18. Les activités de conservation des lémuriens par le Groupe d’Etude et de Recherche sur les Primates de Madagascar (GERP Conservation activities of lemurs by the Madagascar Primate Research Group (GERP- Groupe d’Etude et de Recherche sur les Primates de Madagascar

    Directory of Open Access Journals (Sweden)

    Rose Marie Randrianarison

    2011-10-01

    Full Text Available Le Groupe d’Etude et de Recherche sur les Primates de Madagascar, une association de conservation, a été créée en 1994 grâce à l’initiative des Enseignants Chercheurs et étudiants du Département de Paléontologie et d’Anthropologie Biologique et du Département de Biologie Animale de l’Université d’Antananarivo. Le GERP regroupe actuellement des membres scientifiques multidisciplinaires Malgaches et étrangers dont la majorité d’entre eux est constituée par des primatologues. Les principales actions du GERP se focalisent sur les travaux de recherche sur les Primates Prosimiens de Madagascar, l’établissement de leur plan de conservation, la découverte de nouvelles espèces de lémuriens, la translocation et le transfert des lémuriens vivant dans des milieux défrichés ou précaires, le suivi et l’abondance des lémuriens ainsi que la révision de leurs aires de distribution. Les résultats des recherches effectuées sur la conservation ont permis de publier des articles dans des revues de renommée nationale et internationale sur la Primatologie. En outre, le renforcement de capacité et l’éducation de la communauté de base, des systèmes éducatifs primaires et supérieurs sur la conservation des lémuriens et l’appui aux activités de développement durable de la population locale s’avèrent nécessaires pour que la conservation des lémuriens soit pérenne.The Madagascar Primate Research Group (GERP - Groupe d’Etude et de Recherche sur les Primates de Madagascar is a conservation-focused association created in 1994 by the initiative of researcher lecturers and students from the Department of Paleontology and Biological Anthropology and the Department of Animal Biology of the University of Antananarivo. The GERP membership consists of multidisciplinary scientists, both Malagasy and foreign, the majority of whom are primatologists. The principle actions of the association are focused on research on the

  19. Correction of oral contrast artifacts in CT-based attenuation correction of PET images using an automated segmentation algorithm

    International Nuclear Information System (INIS)

    Ahmadian, Alireza; Ay, Mohammad R.; Sarkar, Saeed; Bidgoli, Javad H.; Zaidi, Habib

    2008-01-01

    Oral contrast is usually administered in most X-ray computed tomography (CT) examinations of the abdomen and the pelvis as it allows more accurate identification of the bowel and facilitates the interpretation of abdominal and pelvic CT studies. However, the misclassification of contrast medium with high-density bone in CT-based attenuation correction (CTAC) is known to generate artifacts in the attenuation map (μmap), thus resulting in overcorrection for attenuation of positron emission tomography (PET) images. In this study, we developed an automated algorithm for segmentation and classification of regions containing oral contrast medium to correct for artifacts in CT-attenuation-corrected PET images using the segmented contrast correction (SCC) algorithm. The proposed algorithm consists of two steps: first, high CT number object segmentation using combined region- and boundary-based segmentation and second, object classification to bone and contrast agent using a knowledge-based nonlinear fuzzy classifier. Thereafter, the CT numbers of pixels belonging to the region classified as contrast medium are substituted with their equivalent effective bone CT numbers using the SCC algorithm. The generated CT images are then down-sampled followed by Gaussian smoothing to match the resolution of PET images. A piecewise calibration curve was then used to convert CT pixel values to linear attenuation coefficients at 511 keV. The visual assessment of segmented regions performed by an experienced radiologist confirmed the accuracy of the segmentation and classification algorithms for delineation of contrast-enhanced regions in clinical CT images. The quantitative analysis of generated μmaps of 21 clinical CT colonoscopy datasets showed an overestimation ranging between 24.4% and 37.3% in the 3D-classified regions depending on their volume and the concentration of contrast medium. Two PET/CT studies known to be problematic demonstrated the applicability of the technique in

  20. impacts des rejets industriels sur les eaux souterraines

    African Journals Online (AJOL)

    USER

    pollution et sont nombreuses, notamment les usines sidérurgiques, métalliques et pétrochimiques. Leurs rejets ont des effets néfastes sur les eaux de la région. Actuellement, les effluents industriels situés dans la région de Berrahal, contiennent d'importantes quantités de produits chimiques organiques et inorganiques et ...

  1. Impact des changements climatiques sur l’agriculture dans la plaine de Jeffara sud-est tunisien

    Directory of Open Access Journals (Sweden)

    Houcine Jeder

    2013-12-01

    Full Text Available Cette étude évalue la vulnérabilité de l’agriculture dans la plaine de Jeffera sud-est tunisien aux changements climatiques en utilisant la méthode Ricardienne. Cette méthode consiste à exprimer les revenus nets agricoles en fonction des variables climatiques, édaphiques et socio-économiques. Ces modèles ricardiens ont été testés sur la base des données d’une enquête réalisée dans le cadre de projet de développement dans la plaine Jeffera pour la compagne agricole 2002-2003.  Ces modèles ont permis d’exprimer d’une part la relation qui existe entre le revenu agricole et les variables climatiques (température et précipitation et d’autre part, d’analyser la sensibilité des revenus agricoles par rapport à ces variables climatiques. Des simulations ont été faites sur la base de scenario A2 résultat de la projection faite par le modèle HadCM3 à l’échelle nationale et régionale de la Tunisie.Les résultats de l’étude ont montré que la relation entre le revenu agricole et le climat est non linéaire. De même, les effets négatifs de certaines options d’adaptation ont montré que  l’agriculture dans la plaine de Jeffera est une agriculture paysanne basée sur le travail familial qui nécessite aujourd’hui un capital financier important et une marge de modernisation afin d’améliorer l’activité agricole dans les années futures. Tandis que les effets positifs de certaines autres options peuvent être servir comme des points de réflexion dans l’élaboration des stratégies d’adaptation aux changements climatiques comme l’utilisation des nouvelles technologies d’irrigation et l’intégration de l’activité de l’élevage dans l’exploitation agricole.

  2. Le reportage en bande dessinée dans la presse actuelle : un autre regard sur le monde

    Directory of Open Access Journals (Sweden)

    Séverine Bourdieu

    2012-05-01

    Full Text Available La bande dessinée sort de sa bulle et s’aventure du côté du réel, du documentaire et du factuel. À partir d’un corpus de reportages en bande dessinée parus dans des périodiques francophones au cours de la dernière décennie, nous nous interrogerons sur les enjeux de cette rencontre entre presse et littérature et sur la légitimité de ce genre en cours de constitution. On montrera ensuite que ce médium mixte, parce qu’il allie ressources graphiques et littéraires, est particulièrement approprié pour restituer à la fois la « chose vue » et l’expérience vécue par le reporter sur le terrain, offrant ainsi au lecteur un autre regard sur le monde.

  3. Phase contrast image synthesis

    DEFF Research Database (Denmark)

    Glückstad, J.

    1996-01-01

    A new method is presented for synthesizing arbitrary intensity patterns based on phase contrast imaging. The concept is grounded on an extension of the Zernike phase contrast method into the domain of full range [0; 2 pi] phase modulation. By controlling the average value of the input phase funct...... function and by choosing appropriate phase retardation at the phase contrast filter, a pure phase to intensity imaging is accomplished. The method presented is also directly applicable in dark field image synthesis....

  4. A Contrast-Based Computational Model of Surprise and Its Applications.

    Science.gov (United States)

    Macedo, Luis; Cardoso, Amílcar

    2017-11-19

    We review our work on a contrast-based computational model of surprise and its applications. The review is contextualized within related research from psychology, philosophy, and particularly artificial intelligence. Influenced by psychological theories of surprise, the model assumes that surprise-eliciting events initiate a series of cognitive processes that begin with the appraisal of the event as unexpected, continue with the interruption of ongoing activity and the focusing of attention on the unexpected event, and culminate in the analysis and evaluation of the event and the revision of beliefs. It is assumed that the intensity of surprise elicited by an event is a nonlinear function of the difference or contrast between the subjective probability of the event and that of the most probable alternative event (which is usually the expected event); and that the agent's behavior is partly controlled by actual and anticipated surprise. We describe applications of artificial agents that incorporate the proposed surprise model in three domains: the exploration of unknown environments, creativity, and intelligent transportation systems. These applications demonstrate the importance of surprise for decision making, active learning, creative reasoning, and selective attention. Copyright © 2017 Cognitive Science Society, Inc.

  5. Optical-based molecular imaging: contrast agents and potential medical applications

    International Nuclear Information System (INIS)

    Bremer, Christoph; Ntziachristos, Vasilis; Weissleder, Ralph

    2003-01-01

    Laser- and sensitive charge-coupled device technology together with advanced mathematical modelling of photon propagation in tissue has prompted the development of novel optical imaging technologies. Fast surface-weighted imaging modalities, such as fluorescence reflectance imaging (FRI) and 3D quantitative fluorescence-mediated tomography have now become available [1, 2]. These technical advances are paralleled by a rapid development of a whole range of new optical contrasting strategies, which are designed to generate molecular contrast within a living organism. The combination of both, technical advances of light detection and the refinement of optical contrast media, finally yields a new spectrum of tools for in vivo molecular diagnostics. Whereas the technical aspects of optical imaging are covered in more detail in a previous review article in ''European Radiology'' [3], this article focuses on new developments in optical contrasting strategies and design of optical contrast agents for in vivo diagnostics. (orig.)

  6. Étude ethnobotanique, activité antifongique in vitro sur Candida ...

    African Journals Online (AJOL)

    SARAH

    Ouattara et al., 2008). ..... (Tecan) ; cette mesure de l'absorbance permettra de déterminer la quantité relative de cellules vivantes et .... Effet des extraits de H. abyssinica sur Candida albicans : Après 72h d'incubation, on observe.

  7. International Development Research Centre Act Loi sur le Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 juin 2009 ... research includes any scientific or technical inquiry or experimentation that is .... data centres and facilities for research and other activ- ities;. (b) initiate and ..... Loi sur la pension de la fonction publique ne s'applique pas aux ...

  8. Afrique-sur-Seine: A new trend in Francophone African literature

    Directory of Open Access Journals (Sweden)

    Наталья Сергеевна Найденова

    2011-09-01

    Full Text Available The article deals with the prerequisites and main stage of formation of a new trend in francophone African literature commonly known as Afrique-sur-Seine. The article outlines its main characteristic features and touches upon its development prospects.

  9. A compressed sensing based reconstruction algorithm for synchrotron source propagation-based X-ray phase contrast computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Melli, Seyed Ali, E-mail: sem649@mail.usask.ca [Department of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK (Canada); Wahid, Khan A. [Department of Electrical and Computer Engineering, University of Saskatchewan, Saskatoon, SK (Canada); Babyn, Paul [Department of Medical Imaging, University of Saskatchewan, Saskatoon, SK (Canada); Montgomery, James [College of Medicine, University of Saskatchewan, Saskatoon, SK (Canada); Snead, Elisabeth [Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK (Canada); El-Gayed, Ali [College of Medicine, University of Saskatchewan, Saskatoon, SK (Canada); Pettitt, Murray; Wolkowski, Bailey [College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, SK (Canada); Wesolowski, Michal [Department of Medical Imaging, University of Saskatchewan, Saskatoon, SK (Canada)

    2016-01-11

    Synchrotron source propagation-based X-ray phase contrast computed tomography is increasingly used in pre-clinical imaging. However, it typically requires a large number of projections, and subsequently a large radiation dose, to produce high quality images. To improve the applicability of this imaging technique, reconstruction algorithms that can reduce the radiation dose and acquisition time without degrading image quality are needed. The proposed research focused on using a novel combination of Douglas–Rachford splitting and randomized Kaczmarz algorithms to solve large-scale total variation based optimization in a compressed sensing framework to reconstruct 2D images from a reduced number of projections. Visual assessment and quantitative performance evaluations of a synthetic abdomen phantom and real reconstructed image of an ex-vivo slice of canine prostate tissue demonstrate that the proposed algorithm is competitive in reconstruction process compared with other well-known algorithms. An additional potential benefit of reducing the number of projections would be reduction of time for motion artifact to occur if the sample moves during image acquisition. Use of this reconstruction algorithm to reduce the required number of projections in synchrotron source propagation-based X-ray phase contrast computed tomography is an effective form of dose reduction that may pave the way for imaging of in-vivo samples.

  10. Safe use of iodinated and gadolinium-based contrast media in current practice in Japan: a questionnaire survey.

    Science.gov (United States)

    Tsushima, Yoshito; Ishiguchi, Tsuneo; Murakami, Takamichi; Hayashi, Hiromitsu; Hayakawa, Katsumi; Fukuda, Kunihiko; Korogi, Yukunori; Sugimoto, Hideharu; Takehara, Yasuo; Narumi, Yoshifumi; Arai, Yasuaki; Kuwatsuru, Ryohei; Yoshimitsu, Kengo; Awai, Kazuo; Kanematsu, Masayuki; Takagi, Ryo

    2016-02-01

    To help establish consensus on the safe use of contrast media in Japan. Questionnaires were sent to accredited teaching hospitals with radiology residency programs. The reply rate was 45.4% (329/724). For contrast-induced nephropathy (CIN), chronic and acute kidney diseases were considered a risk factor in 96.7 and 93.6%, respectively, and dehydration in 73.9%. As preventive actions, intravenous hydration (89.1%) and reduction of iodinated contrast media dose (86.9%) were commonly performed. For nephrogenic systemic fibrosis (NSF), chronic and acute kidney diseases were considered risk factors in 98.5 and 90.6%, respectively, but use of unstable gadolinium-based contrast media was considered a risk factor in only 55.6%. A renal function test was always (63.5% in iodinated; 65.7% in gadolinium) or almost always (23.1; 19.8%) performed, and estimated glomerular filtration rate (eGFR) was the parameter most frequently used (80.8; 82.6%). For the patients with risk factors for acute adverse reaction (AAR), steroid premedication or/and change of contrast medium were frequent preventive actions, but intravenous steroid administration immediately before contrast media use was still performed. Our questionnaire survey revealed that preventive actions against CIN were properly performed based on patients' eGFR. Preventive actions against NSF and AAR still lacked consensus.

  11. In vivo x-ray phase contrast analyzer-based imaging for longitudinal osteoarthritis studies in guinea pigs

    Energy Technology Data Exchange (ETDEWEB)

    Coan, Paola [Faculty of Medicine and Institute of Clinical Radiology, Ludwig-Maximilians University, Munich (Germany); Wagner, Andreas; Mollenhauer, Juergen [Department of Orthopaedics of the University of Jena, Rudolf-Elle-Hospital Eisenberg (Germany); Bravin, Alberto; Diemoz, Paul C; Keyrilaeinen, Jani, E-mail: Paola.Coan@physik.uni-muenchen.d [European Synchrotron Radiation Facility (ESRF), Grenoble (France)

    2010-12-21

    Over the last two decades phase contrast x-ray imaging techniques have been extensively studied for applications in the biomedical field. Published results demonstrate the high capability of these imaging modalities of improving the image contrast of biological samples with respect to standard absorption-based radiography and routinely used clinical imaging techniques. A clear depiction of the anatomic structures and a more accurate disease diagnosis may be provided by using radiation doses comparable to or lower than those used in current clinical methods. In the literature many works show images of phantoms and excised biological samples proving the high sensitivity of the phase contrast imaging methods for in vitro investigations. In this scenario, the applications of the so-called analyzer-based x-ray imaging (ABI) phase contrast technique are particularly noteworthy. The objective of this work is to demonstrate the feasibility of in vivo x-ray ABI phase contrast imaging for biomedical applications and in particular with respect to joint anatomic depiction and osteoarthritis detection. ABI in planar and tomographic modes was performed in vivo on articular joints of guinea pigs in order to investigate the animals with respect to osteoarthritis by using highly monochromatic x-rays of 52 keV and a low noise detector with a pixel size of 47 x 47 {mu}m{sup 2}. Images give strong evidence of the ability of ABI in depicting both anatomic structures in complex systems as living organisms and all known signs of osteoarthritis with high contrast, high spatial resolution and with an acceptable radiation dose. This paper presents the first proof of principle study of in vivo application of ABI. The technical challenges encountered when imaging an animal in vivo are discussed. This experimental study is an important step toward the study of clinical applications of phase contrast x-ray imaging techniques.

  12. Comparison between computed tomography with oral oil-based contrast and laparotomy for gastric cancer staging

    International Nuclear Information System (INIS)

    Marco, S. F.; Garcia-Vila, J. H.; Cervera, J.; Gomez, R.; Piqueras, R. M.; Perona, I.; Escrig, J.; Salvador, J. L.

    2000-01-01

    To compare the utility of conventional computed tomography (CT) with oral oil-based contrast with that of laparotomy in the preoperative staging of gastric cancer. We prospectively studied 41 patients diagnosed as having gastric adenocarcinoma according to the results of endoscopy and biopsy. Applying the TNM classification for gastric cancer staging, we compared the findings in CT associated with oral oil-based contrast and intraoperative staging with definitive postoperative pathological staging. Definitive pathological studies demonstrated that there were 7 stage T1-T2 lesions, 26 stage T3 and 8 stage T4. The assessment of lymph node involvement showed that 10 patients presented stage N0 and 31 stage N1-N3. Ten patients had metastases. The diagnostic reliability for tumor staging according to CT was 56% versus 80% for laparotomy. In the determination of nodal involvement CT had a diagnostic yield of 71% versus 6% for laparotomy. Metastatic disease was correctly diagnosed by CT in 83% of cases versus 88% by laparotomy. There were no statistically significant differences between CT with oral oil-based contrast and laparotomy for the staging of nodal involvement and metastases. However, the CT diagnosis was significantly more reliable than laparotomy for the determination of tumor infiltration. (Author) 21 refs

  13. Gadolinium-based magnetic resonance contrast agents at 7 Tesla: in vitro T1 relaxivities in human blood plasma.

    Science.gov (United States)

    Noebauer-Huhmann, Iris M; Szomolanyi, Pavol; Juras, Vladimír; Kraff, Oliver; Ladd, Mark E; Trattnig, Siegfried

    2010-09-01

    PURPOSE/INTRODUCTION: The aim of this study was to determine the T1 relaxivities (r1) of 8 gadolinium (Gd)-based MR contrast agents in human blood plasma at 7 Tesla, compared with 3 Tesla. Eight commercially available Gd-based MR contrast agents were diluted in human blood plasma to concentrations of 0, 0.25, 0.5, 1, and 2 mmol/L. In vitro measurements were performed at 37 degrees C, on a 7 Tesla and on a 3 Tesla whole-body magnetic resonance imaging scanner. For the determination of T1 relaxation times, Inversion Recovery Sequences with inversion times from 0 to 3500 ms were used. The relaxivities were calculated. The r1 relaxivities of all agents, diluted in human blood plasma at body temperature, were lower at 7 Tesla than at 3 Tesla. The values at 3 Tesla were comparable to those published earlier. Notably, in some agents, a minor negative correlation of r1 with a concentration of up to 2 mmol/L could be observed. This was most pronounced in the agents with the highest protein-binding capacity. At 7 Tesla, the in vitro r1 relaxivities of Gd-based contrast agents in human blood plasma are lower than those at 3 Tesla. This work may serve as a basis for the application of Gd-based MR contrast agents at 7 Tesla. Further studies are required to optimize the contrast agent dose in vivo.

  14. Fronteras e identificaciones nacionales: diálogos desde el Cono Sur

    Directory of Open Access Journals (Sweden)

    Alejandro Grimson

    2014-06-01

    Full Text Available Grimson propone revisitar conceptos sociológicos como “identidades, fronteras o territorios” para adecuar un nuevo marco conceptual a la realidad del Cono Sur de América Latina.

  15. The Impact of Injector-Based Contrast Agent Administration on Bolus Shape and Magnetic Resonance Angiography Image Quality.

    Science.gov (United States)

    Jost, Gregor; Endrikat, Jan; Pietsch, Hubertus

    2017-01-01

    To compare injector-based contrast agent (CA) administration with hand injection in magnetic resonance angiography (MRA). Gadobutrol was administered in 6 minipigs with 3 protocols: (a) hand injection (one senior technician), (b) hand injection (6 less-experienced technicians), and (c) power injector administration. The arterial bolus shape was quantified by test bolus measurements. A head and neck MRA was performed for quantitative and qualitative comparison of signal enhancement. A significantly shorter time to peak was observed for protocol C, whereas no significant differences between protocols were found for peak height and bolus width. However, for protocol C, these parameters showed a much lower variation. The MRA revealed a significantly higher signal-to-noise ratio for injector-based administration. A superimposed strong contrast of the jugular vein was found in 50% of the hand injections. Injector-based CA administration results in a more standardized bolus shape, a higher vascular contrast, and a more robust visualization of target vessels.

  16. The Impact of Injector-Based Contrast Agent Administration on Bolus Shape and Magnetic Resonance Angiography Image Quality

    Directory of Open Access Journals (Sweden)

    Gregor Jost

    2017-04-01

    Full Text Available Objective: To compare injector-based contrast agent (CA administration with hand injection in magnetic resonance angiography (MRA. Methods: Gadobutrol was administered in 6 minipigs with 3 protocols: (a hand injection (one senior technician, (b hand injection (6 less-experienced technicians, and (c power injector administration. The arterial bolus shape was quantified by test bolus measurements. A head and neck MRA was performed for quantitative and qualitative comparison of signal enhancement. Results: A significantly shorter time to peak was observed for protocol C, whereas no significant differences between protocols were found for peak height and bolus width. However, for protocol C, these parameters showed a much lower variation. The MRA revealed a significantly higher signal-to-noise ratio for injector-based administration. A superimposed strong contrast of the jugular vein was found in 50% of the hand injections. Conclusions: Injector-based CA administration results in a more standardized bolus shape, a higher vascular contrast, and a more robust visualization of target vessels.

  17. EFFETS D'UN DEFICIT HYDRIQUE SUR CERTAINS ...

    African Journals Online (AJOL)

    AISA

    Le cotonnier est connu pour sa sensibilité au déficit hydrique. Le présent travail a été initié afin de mesurer les effets de ce facteur chez la variété STAM129A de cotonnier vulgarisée au Togo. L'étude porte sur certains paramètres tels que la hauteur des plantes, la longueur des entrenœuds, le taux de rétention des ...

  18. Un brevet pour la vie : La propriété intellectuelle et ses effets sur le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Un brevet pour la vie : La propriété intellectuelle et ses effets sur le commerce, la biodiversité et le monde rural. Couverture du livre Un brevet pour la vie : La propriété intellectuelle et ses effets sur. Auteur(s):. The Crucible Group. Maison(s) d'édition: CRDI. 1 janvier 1994. ISBN : Épuisé. 120 pages. e-ISBN : 1552503917.

  19. Skull Base Meningiomas and Cranial Nerves Contrast Using Sodium Fluorescein: A New Application of an Old Tool.

    Science.gov (United States)

    da Silva, Carlos Eduardo; da Silva, Vinicius Duval; da Silva, Jefferson Luis Braga

    2014-08-01

    Objective The identification of cranial nerves is one of the most challenging goals in the dissection of skull base meningiomas. The authors present an application of sodium fluorescein (SF) in skull base meningiomas with the purpose of improving the identification of cranial nerves. Design A prospective study within-subjects design. Setting Hospital Ernesto Dornelles, Porto Alegre, Brazil. Participants Patients with skull base meningiomas. Main Outcomes Measures Cranial nerve identification. Results The group of nine meningiomas was composed of one cavernous sinus, three petroclival, one tuberculum sellae, two sphenoid wing, one olfactory groove, and one temporal floor meningioma. The SF enhancement in all tumors was strong, and the contrast with cranial nerves clearly evident. There were one definite olfactory nerve deficit, one transient abducens deficit, and one definite hemiparesis. All lesions were resected (Simpson grades 1 and 2). The analysis of the difference of the delta SF wavelength between the meningiomas and cranial nerve contrast was performed by the Wilcoxon signed rank test and showed p = 0.011. Conclusions The contrast between the enhanced meningiomas and cranial nerves was evident and assisted in the visualization and microsurgical dissection of these structures. The anatomical preservation of these structures was improved using the contrast.

  20. Research on Wavelet-Based Algorithm for Image Contrast Enhancement

    Institute of Scientific and Technical Information of China (English)

    Wu Ying-qian; Du Pei-jun; Shi Peng-fei

    2004-01-01

    A novel wavelet-based algorithm for image enhancement is proposed in the paper. On the basis of multiscale analysis, the proposed algorithm solves efficiently the problem of noise over-enhancement, which commonly occurs in the traditional methods for contrast enhancement. The decomposed coefficients at same scales are processed by a nonlinear method, and the coefficients at different scales are enhanced in different degree. During the procedure, the method takes full advantage of the properties of Human visual system so as to achieve better performance. The simulations demonstrate that these characters of the proposed approach enable it to fully enhance the content in images, to efficiently alleviate the enhancement of noise and to achieve much better enhancement effect than the traditional approaches.

  1. Synchrotron-based DEI for bio-imaging and DEI-CT to image phantoms with contrast agents

    International Nuclear Information System (INIS)

    Rao, Donepudi V.; Swapna, Medasani; Cesareo, Roberto; Brunetti, Antonio; Akatsuka, Tako; Yuasa, Tetsuya; Zhong, Zhong; Takeda, Tohoru; Gigante, Giovanni E.

    2012-01-01

    The introduction of water, physiological, or iodine as contrast agents is shown to enhance minute image features in synchrotron-based X-ray diffraction radiographic and tomographic imaging. Anatomical features of rat kidney, such as papillary ducts, ureter, renal artery and renal vein are clearly distinguishable. Olfactory bulb, olfactory tact, and descending bundles of the rat brain are visible with improved contrast. - Highlights: ► Distinguishable anatomical structures features of rat kidney and rat brain are acquired with Sy-DEI in planar mode. ► Images of a small brain phantom and cylindrical phantom are acquired in tomography mode (Sy-DEI-CT) with contrast agents. ► Sy-DEI and Sy-DEI-CT techniques provide new source of information related to biological microanatomy.

  2. Point de vue de la population sur la réforme du secteur de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Point de vue de la population sur la réforme du secteur de la sécurité palestinien. Dans le cadre de son plan visant à bâtir les institutions de l'État palestinien, le gouvernement de Salam Fayyad s'était engagé en août 2009 à moderniser le secteur de la sécurité palestinien en se fondant sur l'État de droit, sous la ...

  3. CHANGE DETECTION VIA SELECTIVE GUIDED CONTRASTING FILTERS

    Directory of Open Access Journals (Sweden)

    Y. V. Vizilter

    2017-05-01

    Full Text Available Change detection scheme based on guided contrasting was previously proposed. Guided contrasting filter takes two images (test and sample as input and forms the output as filtered version of test image. Such filter preserves the similar details and smooths the non-similar details of test image with respect to sample image. Due to this the difference between test image and its filtered version (difference map could be a basis for robust change detection. Guided contrasting is performed in two steps: at the first step some smoothing operator (SO is applied for elimination of test image details; at the second step all matched details are restored with local contrast proportional to the value of some local similarity coefficient (LSC. The guided contrasting filter was proposed based on local average smoothing as SO and local linear correlation as LSC. In this paper we propose and implement new set of selective guided contrasting filters based on different combinations of various SO and thresholded LSC. Linear average and Gaussian smoothing, nonlinear median filtering, morphological opening and closing are considered as SO. Local linear correlation coefficient, morphological correlation coefficient (MCC, mutual information, mean square MCC and geometrical correlation coefficients are applied as LSC. Thresholding of LSC allows operating with non-normalized LSC and enhancing the selective properties of guided contrasting filters: details are either totally recovered or not recovered at all after the smoothing. These different guided contrasting filters are tested as a part of previously proposed change detection pipeline, which contains following stages: guided contrasting filtering on image pyramid, calculation of difference map, binarization, extraction of change proposals and testing change proposals using local MCC. Experiments on real and simulated image bases demonstrate the applicability of all proposed selective guided contrasting filters. All

  4. Late adverse reactions to intravascular iodine based contrast media

    DEFF Research Database (Denmark)

    Bellin, Marie-France; Stacul, Fulvio; Webb, Judith A W

    2011-01-01

    DEFINITION: Late adverse reactions (LAR) to contrast media (CM) are defined as reactions occurring 1 h to 1 week after exposure. NEED FOR REVIEW: In view of more prospective studies of LAR and new data about their pathophysiology, the Contrast Medium Safety Committee (CMSC) of the European Society...... or delayed reading intradermal). The main risk factors for LAR are a previous reaction to contrast medium, a history of allergy, and interleukin-2 treatment. Most skin reactions are mild or moderate and self-limiting. MANAGEMENT: Management is symptomatic and similar to the management of other drug......-induced skin reactions. To reduce the risk of repeat reactions avoidance of the relevant CM and any cross-reacting agents identified by skin testing is recommended....

  5. Sur des erres de jazz

    OpenAIRE

    Daverat, Xavier

    2007-01-01

    Une opinion commune considère que le jazz vivrait une période de dépérissement ou de ressassement. Cette conception est d’abord basée sur une erreur qui consiste à croire que le jazz évolue uniquement au travers de relèves entre les générations, de substitutions complètes de nouveaux styles à des formes d’expression qui se démoderaient aussitôt, d’instaurations systématiques de nouveaux langages opposés à ceux qui les ont précédés. Au contraire, les caractéristiques de chaque style s’imbrique...

  6. Fabrication and evaluation of tumor-targeted positive MRI contrast agent based on ultrasmall MnO nanoparticles.

    Science.gov (United States)

    Huang, Haitao; Yue, Tao; Xu, Ke; Golzarian, Jafar; Yu, Jiahui; Huang, Jin

    2015-07-01

    Gd(III) chelate is currently used as positive magnetic resonance imaging (MRI) contrast agent in clinical diagnosis, but generally induces the risk of nephrogenic systemic fibrosis (NSF) due to the dissociated Gd(3+) from Gd(III) chelates. To develop a novel positive MRI contrast agent with low toxicity and high sensitivity, ultrasmall MnO nanoparticles were PEGylated via catechol-Mn chelation and conjugated with cRGD as active targeting function to tumor. Particularly, the MnO nanoparticles with a size of ca. 5nm were modified by α,β-poly(aspartic acid)-based graft polymer containing PEG and DOPA moieties and, meanwhile, conjugated with cRGD to produce the contrast agent with a size of ca. 100nm and a longitudinal relaxivity (r1) of 10.2mM(-1)S(-1). Such nanoscaled contrast agent integrated passive- and active-targeting function to tumor, and its efficient accumulation behavior in tumor was verified by in vivo distribution study. At the same time, the PEG moiety played a role of hydrophilic coating to improve the biocompatibility and stability under storing and physiological conditions, and especially might guarantee enough circulation time in blood. Moreover, in vivo MRI revealed a good and long-term effect of enhancing MRI signal for as-fabricated contrast agent while cell viability assay proved its acceptable cytotoxicity for MRI application. On the whole, the as-fabricated PEGylated and cRGD-functionalized contrast agent based on ultrasmall MnO nanoparticles showed a great potential to the T1-weighted MRI diagnosis of tumor. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

  7. Optimisation of a propagation-based x-ray phase-contrast micro-CT system

    Science.gov (United States)

    Nesterets, Yakov I.; Gureyev, Timur E.; Dimmock, Matthew R.

    2018-03-01

    Micro-CT scanners find applications in many areas ranging from biomedical research to material sciences. In order to provide spatial resolution on a micron scale, these scanners are usually equipped with micro-focus, low-power x-ray sources and hence require long scanning times to produce high resolution 3D images of the object with acceptable contrast-to-noise. Propagation-based phase-contrast tomography (PB-PCT) has the potential to significantly improve the contrast-to-noise ratio (CNR) or, alternatively, reduce the image acquisition time while preserving the CNR and the spatial resolution. We propose a general approach for the optimisation of the PB-PCT imaging system. When applied to an imaging system with fixed parameters of the source and detector this approach requires optimisation of only two independent geometrical parameters of the imaging system, i.e. the source-to-object distance R 1 and geometrical magnification M, in order to produce the best spatial resolution and CNR. If, in addition to R 1 and M, the system parameter space also includes the source size and the anode potential this approach allows one to find a unique configuration of the imaging system that produces the required spatial resolution and the best CNR.

  8. Nueva especie del género Arctosa (Araneae, Lycosidae del sur de Brazil

    Directory of Open Access Journals (Sweden)

    Estevam Luís Cruz da Silva

    2008-12-01

    Full Text Available Se describe e ilustra una nueva especie del género Arctosa C. L. a Koch, 1848, en base a material procedente de Sapiranga, sur del Brasil. Los miembros de este género por lo general excavan refugios pequeños en los bordes arenosos de los lagos, sin embargo, esta nueva especie se encuentra debajo de rocas en los bordes de rios pequeños. Se puede encontrar hembras con ootecas y machos durante todo el año, aunque son más abundantes en el período del verano.

  9. Les impacts de la guerre du Việt Nam sur les forêts d’A Lưới

    OpenAIRE

    Robert-Charmeteau, Amélie

    2015-01-01

    Au cours de la guerre du Việt Nam, l’actuel district d’A Lưới (province de Thừa Thiên Huế, Việt Nam central), traversé par la piste Hồ Chí Minh, subit de nombreux épandages d’herbicides et pilonnages. Les forêts sont une cible privilégiée. Mais les conséquences de ces pratiques militaires sur les sylvosystèmes sont sujettes à controverses. Pour identifier objectivement le poids de la guerre sur les dynamiques paysagères, l’étude se fonde sur une analyse diachronique régressive des paysages et...

  10. Amélioration du système de suivi de l'information sur la santé ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le système de suivi de l'information sur la santé communautaire (CHITS) est un système électronique d'information sur la santé publique mis en place par les services de santé de Pasay City en 2004. Le cinquième des habitants des bidonvilles du grand Manille étant établis à Pasay City, ce système dessert une population ...

  11. Evaluation of contrast reproduction method based on the anatomical guidance of the cerebral images reconstruction in positron emission tomography; Evaluation d'une methode de restitution de contraste basee sur le guidage anatomique de la reconstruction des images cerebrales en tomographie par emission de positons

    Energy Technology Data Exchange (ETDEWEB)

    Bataille, F

    2007-04-15

    Positron emission tomography is a medical imaging modality providing in-vivo volumetric images of functional processes of the human body, which is used for the diagnosis and the following of neuro degenerative diseases. PET efficiency is however limited by its poor spatial resolution, which generates a decrease of the image local contrast and leads to an under-estimation of small cerebral structures involved in the degenerative mechanism of those diseases. This so-called partial volume effect degradation is usually corrected in a post-reconstruction processing framework through the use of anatomical information, whose spatial resolution allows a better discrimination between functional tissues. However, this kind of method has the major drawback of being very sensitive to the residual mismatches on the anatomical information processing. We developed in this thesis an alternative methodology to compensate for the degradation, by incorporating in the reconstruction process both a model of the system impulse response and an anatomically-based image prior constraint. This methodology was validated by comparison with a post-reconstruction correction strategy, using data from an anthropomorphic phantom acquisition and then we evaluated its robustness to the residual mismatches through a realistic Monte Carlo simulation corresponding to a cerebral exam. The proposed algorithm was finally applied to clinical data reconstruction. (author)

  12. Evaluation of contrast reproduction method based on the anatomical guidance of the cerebral images reconstruction in positron emission tomography; Evaluation d'une methode de restitution de contraste basee sur le guidage anatomique de la reconstruction des images cerebrales en tomographie par emission de positons

    Energy Technology Data Exchange (ETDEWEB)

    Bataille, F

    2007-04-15

    Positron emission tomography is a medical imaging modality providing in-vivo volumetric images of functional processes of the human body, which is used for the diagnosis and the following of neuro degenerative diseases. PET efficiency is however limited by its poor spatial resolution, which generates a decrease of the image local contrast and leads to an under-estimation of small cerebral structures involved in the degenerative mechanism of those diseases. This so-called partial volume effect degradation is usually corrected in a post-reconstruction processing framework through the use of anatomical information, whose spatial resolution allows a better discrimination between functional tissues. However, this kind of method has the major drawback of being very sensitive to the residual mismatches on the anatomical information processing. We developed in this thesis an alternative methodology to compensate for the degradation, by incorporating in the reconstruction process both a model of the system impulse response and an anatomically-based image prior constraint. This methodology was validated by comparison with a post-reconstruction correction strategy, using data from an anthropomorphic phantom acquisition and then we evaluated its robustness to the residual mismatches through a realistic Monte Carlo simulation corresponding to a cerebral exam. The proposed algorithm was finally applied to clinical data reconstruction. (author)

  13. Crítica a los mitos acerca de las migraciones centroamericanas a la frontera sur de México

    Directory of Open Access Journals (Sweden)

    Rodolfo Casillas R.

    1988-09-01

    Full Text Available Este trabajo intenta plantear y enfocar los distintos fenómenos migratorios que ocurren en la frontera sur de México. Como punto de partida, presenta algunas de las ideas que han proliferado en torno a las migraciones hacia la frontera sur de México, muchas de las cuales son comunes a las de otros contextos fronterizos. Como parte de un proyecto de investigación desarrollado se hace uso de las indagaciones de campo realizadas en la región del Soconusco, en el Estado de Chiapas. En base a los resultados debe enfatizarse que la carencia de conocimientos requiere de estudios más profundos y diversos enfocados al análisis de otros flujos migratorios y se puede concluir que la forma adecuada de enfrentar este fenómeno no radica en las medidas de control, sino más bien en la oportuna contribución para solucionar los problemas de origen.

  14. Turistas hispanohablantes en Corea del Sur

    OpenAIRE

    Arroyo Herrera, Javier

    2016-01-01

    Dada la evolución económica que ha experimentado en los últimos años y el aumento de las llegadas de turistas internacionales debido a fenómenos como el Hallyu, Corea del Sur se está convirtiendo en un foco de atención turística que requiere de estudios para conocer mejor su turismo y la importancia que la cultura popular supone para éste. La presente investigación recopila los elementos más destacables del turismo surcoreano y demuestra la influencia que la „ola coreana‟ provoca en sus segui...

  15. Preclinical animal acute toxicity studies of new developed MRI contrast agent based on gadolinium

    Science.gov (United States)

    Nam, I. F.; Zhuk, V. V.

    2015-04-01

    Acute toxicity test of new developed MRI contrast agent based on disodium salt of gadopentetic acid complex were carried out on Mus musculus and Sprague Dawley rats according to guidelines of preclinical studies [1]. Groups of six animals each were selected for experiment. Death and clinical symptoms of animals were recorded during 14 days. As a result the maximum tolerated dose (MTD) for female mice is 2.8 mM/kg of body weight, male mice - 1.4 mM/kg, female rats - 2.8 mM/kg, male rats - 5.6 mM/kg of body weight. No Observed Adverse Effect Dose (NOAEL) for female mice is 1.4 mM/kg, male mice - 0.7 mM/kg, male and female rats - 0.7 mM/kg. According to experimental data new developed MRI contrast agent based on Gd-DTPA complex is low-toxic.

  16. Controlling cavitation-based image contrast in focused ultrasound histotripsy surgery.

    Science.gov (United States)

    Allen, Steven P; Hall, Timothy L; Cain, Charles A; Hernandez-Garcia, Luis

    2015-01-01

    To develop MRI feedback for cavitation-based, focused ultrasound, tissue erosion surgery (histotripsy), we investigate image contrast generated by transient cavitation events. Changes in GRE image intensity are observed while balanced pairs of field gradients are varied in the presence of an acoustically driven cavitation event. The amplitude of the acoustic pulse and the timing between a cavitation event and the start of these gradient waveforms are also varied. The magnitudes and phases of the cavitation site are compared with those of control images. An echo-planar sequence is used to evaluate histotripsy lesions in ex vivo tissue. Cavitation events in water cause localized attenuation when acoustic pulses exceed a pressure threshold. Attenuation increases with increasing gradient amplitude and gradient lobe separation times and is isotropic with gradient direction. This attenuation also depends upon the relative timing between the cavitation event and the start of the balanced gradients. These factors can be used to control the appearance of attenuation while imaging ex vivo tissue. By controlling the timing between cavitation events and the imaging gradients, MR images can be made alternately sensitive or insensitive to cavitation. During therapy, these images can be used to isolate contrast generated by cavitation. © 2014 Wiley Periodicals, Inc.

  17. Etude sur les sources de la passion du Palatinus

    NARCIS (Netherlands)

    Maas, Paul Marie

    1942-01-01

    Notre étude sur la Passion du Palatinus étant terminée, nous voudrions ajouter un aperçu des principaux résultats obtenus. Quelque modestes qu'ils soient, nous espérons que ces résultats pouront contribuer à faire mieux comprendre les rapports obscurs qui existent entre notre Passion et ses sources

  18. Rapport annuel au Parlement Loi sur la protection des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    3) l'innovation, la politique et la science, 4) la recherche pour l'équité en santé et ... Le Centre n'a reçu aucune plainte au sujet de l'administration de la Loi sur la ... Art. 18(2). VI. Extentions/. Prorogations des délais. 30 days or under /. 30 jours ...

  19. L’engagement civique des adolescents au prisme de leurs vlogues sur l’intimidation

    OpenAIRE

    Caron, Caroline

    2016-01-01

    Cet article présente les résultats d’une analyse par théorisation ancrée de 55 vlogues produits par des adolescents franco-québécois pour dénoncer l’intimidation et diffusés sur YouTube entre 2010 et 2014. Il vise à clarifier le concept d’engagement civique des jeunes en ligne à partir d’une démarche méthodologique originale qui s’appuie sur la sociosémiotique de Gunther Kress. Les résultats montrent que chaque vlogue s’inscrit dans une chaîne d’invites et de réponses, produisant ainsi un esp...

  20. Effets de la formation sur la violence conjugale

    Science.gov (United States)

    Zaher, Eman; Keogh, Kelly; Ratnapalan, Savithiri

    2014-01-01

    Résumé Objectif Décrire et évaluer l’efficacité de la formation concernant la violence conjugale pour améliorer les connaissances et permettre la reconnaissance et la prise en charge par les médecins des femmes victimes de violence. Sources des données On a fait une recension dans la base de données des révisions systématiques de Cochrane, MEDLINE, PubMed, PsycINFO, ERIC et EMBASE pour trouver des articles publiés entre le 1e janvier 2000 et le 1e novembre 2012. Des recherches manuelles ont complété cette recension pour cerner des articles pertinents à l’aide d’une stratégie de recherche combinant des textes, mots et expressions MeSH. Sélection des études On a choisi des études randomisées contrôlées qui portaient sur des interventions éducatives à l’intention des médecins et fournissaient des données sur les effets des interventions. Synthèse On a inclus 9 études randomisées contrôlées qui décrivaient différentes approches pédagogiques et diverses mesures des résultats. Trois études examinaient les effets d’interventions éducatives pour des médecins en formation postdoctorale et ont constaté une augmentation des connaissances, mais il n’y a eu aucun changement dans le comportement en ce qui a trait à l’identification des victimes de violence conjugale. Six études portaient sur des interventions éducatives pour des médecins en pratique active. Trois d’entre elles utilisaient une approche à multiples facettes pour les médecins, qui combinait une formation ainsi que des interventions de soutien de la part du système pour changer les comportements des médecins, comme une sensibilisation générale accrue à la violence conjugale au moyen de brochures et d’affiches, des aide-mémoire pour rappeler aux médecins comment identifier les victimes, des moyens pour faciliter l’accès des médecins à des services de soutien pour les victimes, la réalisation d’audits et la fourniture de rétroaction. Les

  1. Ayllón, Bruno. La cooperación Sur-Sur y triangular en América Latina. Políticas afirmativas y prácticas transformadoras. Madrid, 2013. Editora Catarata / Universidad Complutense de Madrid (IUDC-UCM), 2013, 246p. ISBN: 978–84–8319–441–6

    OpenAIRE

    Dolcetti, Michele; Universidad Complutense de Madrid

    2013-01-01

    Três anos após a publicação de “La Cooperación Sur-Sur en Latinoamérica. Utopía y realidad”, a equipe de pesquisa do IUDC-UCM editou “La Cooperación Sur-Sur en América Latina. Políticas afirmativas y práticas transformadoras”, texto imprescindível para o estudo da Cooperação Sul-Sul (CSS) no espaço ibero-americano. Em 2010 a análise da CSS era incipiente e suas definições pouco consolidadas; falava-se de “estado embrionário da CSS” e de “doadores emergentes”: definições que expressavam plenam...

  2. Les migrations en Basse Casamance (Sénégal) : Projet d'une recherche multidisciplinaire sur les facteurs socio-économiques favorisant la migration en Basse Casamance et sur ses conséquences pour les lieux d'origine : rapport final

    NARCIS (Netherlands)

    Jonge, de K.; Klei, van der J.; Meilink, H.A.; Storm, R.

    1978-01-01

    Deux des limitations majeurs des études sur les migration en Afrique Noire sont leur orientation axée vers l'analyse des caractéristiques et motivations individuelles des migrants et la négligence de l'évaluation des conséquences sur les lieux de départ. Ce rapport, résultat d'une recherche menée en

  3. Comparison of Accuracy of Contrast Enhanced Computed Tomography with Accuracy of Non-Contrast Magnetic Resonance Imaging in Evaluation of Local Extension of Base of Tongue Malignancies

    Directory of Open Access Journals (Sweden)

    Ketan Rathod

    2018-01-01

    Full Text Available Diagnosis of base of tongue malignancy can be obtained through clinical examination and biopsy. Magnetic Resonance Imaging (MRI and Computed Tomography (CT are used to detect its local extension, nodal spread and distant metastases. The main aim of study was to compare the accuracy of MRI and contrast enhanced CT in determining the local extent of base of tongue malignancy. Twenty five patients, biopsy proven cases of squamous cell carcinoma of base of tongue were taken. 1.5 Tesla Magnetic Resonance Unit with T2 weighted axial, coronal image; T1 weighted axial, coronal image; and STIR (Short tau inversion recovery axial and coronal images were used. 16 slice Computed Tomography unit with non-contrast and contrast enhanced images were used. Accuracy of CT to detect midline crossing: 50%; accuracy of MRI to detect midline crossing: 100%; accuracy of CT to detect anterior extension: 92%; accuracy of MRI to detect anterior extension: 100%; accuracy of CT to detect tonsillar fossa invasion: 83%; accuracy of MRI to detect tonsillar fossa invasion: 100%; accuracy of CT to detect oro pharyngeal spread: 83%; accuracy of MRI to detect oro pharyngeal spread: 100%; accuracy of CT to detect bone involvement: 20%; accuracy of MRI to detect bone involvement: 100%. MRI proved to be a better investigation than CT, in terms of evaluation of depth of invasion, presence of bony involvement, extension to opposite side, anterior half of tongue, tonsillar fossa, floor of mouth or oropharynx.

  4. Étude sur la nutrition menée dans des écoles de la Grenade : des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude sur la nutrition menée dans des écoles de la Grenade : des données probantes pour éclairer les politiques. Selon l'étude sur la charge mondiale de morbidité de l'Organisation mondiale de la santé, ce sont les maladies non transmissibles liées à l'obésité qui pèseront le plus dans la charge de morbidité des pays à ...

  5. Effets des émissions radiophoniques sur la perception de la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... vue exprimés sur la biotechnologie agricole et de l'intérêt que les médias portent à la question, ... et les données seront soumises à une analyse aussi bien qualitative que quantitative. ... From “gender as usual” to “gender as transformative”.

  6. Renforcement de la recherche sur les politiques et du plaidoyer ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Nouveau webinaire IWRA/CRDI sur les changements climatiques et la gestion adaptive de l'eau. L'Association internationale de ressources en eau (IWRA), en étroite collaboration avec le CRDI, organise un webinaire intitulé "Changements climatiques et gestion adaptive de l'eau: des... Voir davantageNouveau webinaire ...

  7. T(2) relaxation time of hyaline cartilage in presence of different gadolinium-based contrast agents.

    Science.gov (United States)

    Wiener, Edzard; Settles, Marcus; Diederichs, Gerd

    2010-01-01

    The transverse relaxation time, T(2), of native cartilage is used to quantify cartilage degradation. T(2) is frequently measured after contrast administration, assuming that the impact of gadolinium-based contrast agents on cartilage T(2) is negligible. To verify this assumption the depth-dependent variation of T(2) in the presence of gadopentetate dimeglumine, gadobenate dimeglumine and gadoteridol was investigated. Furthermore, the r(2)/r(1) relaxivity ratios were quantified in different cartilage layers to demonstrate differences between T(2) and T(1) relaxation effects. Transverse high-spatial-resolution T(1)- and T(2)-maps were simultaneously acquired on a 1.5 T MR scanner before and after contrast administration in nine bovine patellae using a turbo-mixed sequence. The r(2)/r(1) ratios were calculated for each contrast agent in cartilage. Profiles of T(1), T(2) and r(2)/r(1) across cartilage thickness were generated in the absence and presence of contrast agent. The mean values in different cartilage layers were compared for global variance using the Kruskal-Wallis test and pairwise using the Mann-Whitney U-test. T(2) of unenhanced cartilage was 98 +/- 5 ms at 1 mm and 65 +/- 4 ms at 3 mm depth. Eleven hours after contrast administration significant differences (p cartilage thickness were close to 1.0 (range 0.9-1.3). At 1.5 T, T(2) decreased significantly in the presence of contrast agents, more pronounced in superficial than in deep cartilage. The change in T(2) relaxation rate was similar to the change in T(1). Cartilage T(2) measurements after contrast administration will lead to systematic errors in the quantification of cartilage degradation. 2010 John Wiley & Sons, Ltd.

  8. High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Zhao; Gao, Kun; Chen, Jian; Wang, Dajiang; Wang, Shenghao; Chen, Heng; Bao, Yuan; Shao, Qigang; Wang, Zhili, E-mail: wangnsrl@ustc.edu.cn [National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029 (China); Zhang, Kai [Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China); Zhu, Peiping; Wu, Ziyu, E-mail: wuzy@ustc.edu.cn [National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China and Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China)

    2015-02-15

    Purpose: Grating-based x-ray phase contrast imaging is considered as one of the most promising techniques for future medical imaging. Many different methods have been developed to retrieve phase signal, among which the phase stepping (PS) method is widely used. However, further practical implementations are hindered, due to its complex scanning mode and high radiation dose. In contrast, the reverse projection (RP) method is a novel fast and low dose extraction approach. In this contribution, the authors present a quantitative analysis of the noise properties of the refraction signals retrieved by the two methods and compare their sensitivities. Methods: Using the error propagation formula, the authors analyze theoretically the signal-to-noise ratios (SNRs) of the refraction images retrieved by the two methods. Then, the sensitivities of the two extraction methods are compared under an identical exposure dose. Numerical experiments are performed to validate the theoretical results and provide some quantitative insight. Results: The SNRs of the two methods are both dependent on the system parameters, but in different ways. Comparison between their sensitivities reveals that for the refraction signal, the RP method possesses a higher sensitivity, especially in the case of high visibility and/or at the edge of the object. Conclusions: Compared with the PS method, the RP method has a superior sensitivity and provides refraction images with a higher SNR. Therefore, one can obtain highly sensitive refraction images in grating-based phase contrast imaging. This is very important for future preclinical and clinical implementations.

  9. High sensitivity phase retrieval method in grating-based x-ray phase contrast imaging

    International Nuclear Information System (INIS)

    Wu, Zhao; Gao, Kun; Chen, Jian; Wang, Dajiang; Wang, Shenghao; Chen, Heng; Bao, Yuan; Shao, Qigang; Wang, Zhili; Zhang, Kai; Zhu, Peiping; Wu, Ziyu

    2015-01-01

    Purpose: Grating-based x-ray phase contrast imaging is considered as one of the most promising techniques for future medical imaging. Many different methods have been developed to retrieve phase signal, among which the phase stepping (PS) method is widely used. However, further practical implementations are hindered, due to its complex scanning mode and high radiation dose. In contrast, the reverse projection (RP) method is a novel fast and low dose extraction approach. In this contribution, the authors present a quantitative analysis of the noise properties of the refraction signals retrieved by the two methods and compare their sensitivities. Methods: Using the error propagation formula, the authors analyze theoretically the signal-to-noise ratios (SNRs) of the refraction images retrieved by the two methods. Then, the sensitivities of the two extraction methods are compared under an identical exposure dose. Numerical experiments are performed to validate the theoretical results and provide some quantitative insight. Results: The SNRs of the two methods are both dependent on the system parameters, but in different ways. Comparison between their sensitivities reveals that for the refraction signal, the RP method possesses a higher sensitivity, especially in the case of high visibility and/or at the edge of the object. Conclusions: Compared with the PS method, the RP method has a superior sensitivity and provides refraction images with a higher SNR. Therefore, one can obtain highly sensitive refraction images in grating-based phase contrast imaging. This is very important for future preclinical and clinical implementations

  10. artographie des risques naturels dans les Pyrénées et sur leur piémont

    Directory of Open Access Journals (Sweden)

    Jean-Marc ANTOINE

    1994-12-01

    Full Text Available Les recherches menées par le CIMA URA-366 sur les risques naturels dans les Pyrénées privilégient leur dimension historique et l’étude des contextes socio-écologiques dans lesquels ils s’inscrivent. Cette approche novatrice débouche sur une cartographie historique des phénomènes, conjugant plusieurs niveaux d’analyse spatiotemporels.

  11. Une stratégie de développement fondée sur l’innovation

    OpenAIRE

    Schut, Pierre-Olaf

    2013-01-01

    Petzl est une entreprise du bassin Grenoblois dont l’activité est centrée sur la production de matériel de montagne. Aujourd’hui, l’entreprise est une importante PMI internationale de l’industrie des articles de sport, portée par des produits tels que les lampes frontales, les harnais d’escalade et les engins mécaniques assurant la progression sur corde. Hier, elle était une simple entreprise artisanale familiale, proposant du matériel de spéléologie. La présente monographie révèle l’évolutio...

  12. Influence de colorants dissous sur le point de clarification de phases nématiques

    OpenAIRE

    Diot , P.; Foitzik , J.K.; Haase , W.

    1985-01-01

    Les systèmes « guest-host » dopés avec des colorants dichroïques sont importants pour certains types d'afficheurs. Ce travail rapporte l'influence des propriétés des colorants dissous sur le comportement de clarification. Les phases nématiques suivantes ont été choisies : CB-7, PCH-7 et ZLI-1083, un mélange eutectique ternaire de PCH-3, PCH-5 et PCH-7; quatre dérivés anthraquinoniques ont été choisis comme colorants. L'influence des colorants sur le comportement de clarification est discutée ...

  13. L'incidence des pesticides sur les producteurs de pommes de terre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 janv. 2011 ... L'incidence des pesticides sur les producteurs de pommes de terre de l'Équateur ... L'entreposage des pesticides dans les bâtiments de ferme, des installations .... (les pesticides) : L'intoxication par les pesticides en Équateur.

  14. Analyse des politiques sur la grippe aviaire | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... à prévenir sa transmission à l'humain et à renforcer les mesures nationales de préparation en cas de pandémie de grippe aviaire. Le Partenariat de recherche sur l'influenza aviaire en Asie (APAIR) regroupe des organismes de recherche nationaux ainsi que des ministères de la Chine, du Cambodge, de l'Indonésie, ...

  15. América del Sur en la Apertura, Evidencias de un Modelo Global

    Directory of Open Access Journals (Sweden)

    Pablo Guillermo Butteri

    2006-01-01

    Full Text Available Los procesos de apertura en los que se involucró Sur América desde la década de los ochenta han sido determinantes en la evolución de numerosas variables ma c roe conómi c a s de los pa í s e s, particularmente en los campos del empleo, grado de apertura, competitividad, crecimiento, entre otras. La evolución de dichas variables ha sido disímil en todos los países que componen América del Sur, y dispar si se compara con los cambios registrados en los países de altos ingresos como lo son los miembros de la Organización para la Cooperación y Desarrollo Económico (OECD. En este artículo, además de hacer un análisis de la evolución de las principales variables macroeconómicas para Sur América y compararlas con otros países, busca estudiar la relación entre la tasa de cambio real (ITCR, el crecimiento, y el desempleo, enfatizando en el último aspecto, el cual ha sido poco analizado en la literatura económica de América del Sur. Para alcanzar esto, se estimó un modelo de datos panel que mide el grado de dependencia existente entre el desempleo, el ITCR y la actividad económica entre otras, para el periodo comprendido entre 1988 y 2002. Los principales resultados muestran que una mayor reevaluación (con dos años de anticipación y un menor crecimiento derivan en mayores tasas de desempleo, y aparentemente cambios en la tasa de inflación no afectan la última variable.

  16. Suivi sur le programme de mentorat de journalistes scientifiques des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12 oct. 2010 ... Godefroy Chabi, un jeune journaliste scientifique, se présente à l'accueil d'un ... Il doit rédiger un article sur l'éducation et les droits de l'homme. ... et de Agence suédoise de coopération internationale au développement.

  17. Effets du vieillisement de la batterie Li-ion sur les performances d'un vehicule recreatif hybride branchable a trois roues

    Science.gov (United States)

    Nadeau, Jonathan

    La prediction de l'evolution du vieillissement de la batterie lithium-ion est source d'un grand defi, dans les applications liees aux vehicules electriques et hybrides. Sa meconnaissance est un risque considerable compromettant la viabilite d'un tel systeme. Invoquant les couts substantiels de la densite d'energie, liee a la degradation considerable des performances de la batterie au cours de sa duree de vie, il devient important d'en tenir compte des le processus de conception. La dependance de la strategie de controle du vehicule aux parametres de la batterie justifie aussi la necessite d'une telle prediction. Il est connu que le vieillissement, sensible aux facteurs tels que le courant, la temperature et la profondeur de decharge, a un impact considerable sur la perte de capacite de la batterie ainsi que sur l'augmentation de la resistance interne. Le premier est directement lie a l'autonomie electrique du vehicule, alors que le second mene a une surchauffe de la batterie, a une augmentation des pertes en puissance qui se manifeste par une diminution de la tension de bus. A cet egard, implique dans la conception d'un vehicule recreatif hybride branchable a trois roues, le Centre de Technologies Avancees s'interesse a l'etude du vieillissement de la batterie Li-ion pour une telle application. Pour ce faire, au contraire de la plupart des estimations empiriques de la duree de vie, basees sur des profils de decharge a courant constant, un profil de courant plus approprie pour l'application donnee, base sur un cycle de vitesse representatif de la conduite d'une motocyclette, a ete utilise. Par le biais d'un simulateur complet du vehicule, le cycle de courant a ete extrait du cycle de vitesse. Ainsi, les travaux menes impliquent l'analyse experimentale de la decharge cyclique de quatre cellules LiFePO 4. Pendant plus de 1400 cycles, un banc d'essai complet a permis l'acquisition de la capacite, de la resistance interne, du courant, de la tension ainsi que de la

  18. New K-Ar ages of altered rocks from Paramillos Sur and Norte: Interpretation of the results

    International Nuclear Information System (INIS)

    Koukharsky, Magdalena; Brodtkorb, Alejo; Munizaga, Francisco

    1998-01-01

    The whole-rock K-Ar dates from porphyry copper prospects of Paramillos Sur (phyllic and potasic alteration zones) and Paramillos Norte (propilitic zone) are reported. Radiometric data yielded 17,8 ± 0,9 Ma, 15,8 ± 1,0 Ma and 15,2 ± 0,5 Ma in Paramillos Sur, and 17,3 ± 0,7 Ma in Paramillos Norte, which can be added to an previously reported age of 16,4 ± 0,3 Ma. These data are in agreement with isotopic ages from non altered or non mineralized magmatic rocks of the region. When the isotopic ages and petrographic characteristics of the dated rocks are considered, two alteration-mineralization events are suggested for Paramillos Sur prospect. However this possibility needs to be confirmed by means of future studies, in view of the reduced interval between these events when compared with the analytical errors. (author)

  19. Réflexion sur l’origine du processus de segmentation du marche du travail

    Directory of Open Access Journals (Sweden)

    Attia Nicole

    2006-01-01

    Full Text Available (francuski Ce travail propose une réflexion sur l'origine du processus de segmentation du marché du travail par rapport à l'entreprise. Se situe-t-elle au sein même de l'entreprise ou en amont, c'est à dire entre les entreprises? Cela revient à se demander si on peut avoir une approche microéconomique ou macroéconomique de la segmentation et, à s'interroger sur le rôle réel tenu par les firmes dans le processus. Déterminant pour la théorie, ce rôle est à repenser selon la réponse apportée à notre question.

  20. Motion contrast using optical coherence tomography

    Science.gov (United States)

    Fingler, Jeffrey Paul

    Diagnosis of ophthalmic diseases like age-related macular degeneration is very important for treatment of the disease as well as the development of future treatments. Optical coherence tomography (OCT) is an optical interference technique which can measure the three-dimensional structural information of the reflecting layers within a sample. In retinal imaging, OCT is used as the primary diagnostic tool for structural abnormalities such as retinal holes and detachments. The contrast within the images of this technique is based upon reflectivity changes from different regions of the retina. This thesis demonstrates the developments of methods used to produce additional contrast to the structural OCT images based on the tiny fluctuations of motion experienced by the mobile scatterers within a sample. Motion contrast was observed for motions smaller than 50 nm in images of a variety of samples. Initial contrast method demonstrations used Brownian motion differences to separate regions of a mobile Intralipid solution from a static agarose gel, chosen in concentration to minimize reflectivity contrast. Zebrafish embryos in the range of 3-4 days post fertilization were imaged using several motion contrast methods to determine the capabilities of identifying regions of vascular flow. Vasculature identification was demonstrated in zebrafish for blood vessels of all orientations as small as 10 microns in diameter. Mouse retinal imaging utilized the same motion contrast methods to determine the contrast capabilities for motions associated with vasculature within the retina. Improved contrast imaging techniques demonstrated comparable images to fluorescein angiography, the gold standard of retinal vascular imaging. Future studies can improve the demonstrated contrast analysis techniques and apply them towards human retinal motion contrast imaging for ophthalmic diagnostic purposes.

  1. Enquête sur les attitudes de la population à l'égard des réformes du ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Enquête sur les attitudes de la population à l'égard des réformes du secteur de la sécurité dans le monde arabe. Une des constantes observées dans les fluctuations du Printemps arabe a été l'accroissement de l'influence de l'opinion publique sur les politiques publiques. Rares sont les domaines d'intérêt public qui ont eu ...

  2. Enquête sur l'utilisation du téléphone mobile pour le développement ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Enquête sur l'utilisation du téléphone mobile pour le développement des petites et microentreprises au Ghana. Les technologies de l'information et de la communication (TIC) constituent maintenant des facteurs clés du progrès social et économique. Bien qu'on se soit en grande partie intéressé à l'incidence des TIC sur les ...

  3. The Value of Contrast Echocardiography

    Directory of Open Access Journals (Sweden)

    Shannon C. Treiber

    2016-01-01

    Full Text Available Purpose: There is much evidence-based research proving the effectiveness of contrast echocardiography, but there are still questions and concerns about its specific uses. This study tested the effectiveness of contrast echocardiography in defining the left ventricular endocardial border. Methods: From 30 patients, a total of 60 echocardiograms –– 30 with and 30 without use of contrast –– were retrospectively reviewed by four blinded cardiologists with advanced training in echocardiography. No single cardiologist reviewed contrast and noncontrast images of the same patient. Each set of 30 echocardiograms was then studied for wall-motion scoring. Visualization of left ventricular wall segments and a global visualization confidence level of interpretation were recorded. Results: Of all wall segments (N = 510, 91% were visualized in echocardiograms with use of contrast, whereas 75% of the walls were visualized in echocardiograms without contrast (P < 0.001. Of 30 examinations, 17 contrast echocardiograms were read with high confidence compared to 6 without contrast use (P = 0.004. The number of walls visualized with contrast was increased in 18 patients (60%, whereas noncontrast echocardiograms yielded more visualized walls in 6 patients (20%, P = 0.002. Conclusions: This study demonstrates that contrast is valuable to echocardiographic imaging. Its use should be supported throughout echocardiography clinics and encouraged in certain patients for whom resting and stress echocardiography results without contrast often prove uninterpretable.

  4. Saisonalité et autosubsistance alimentaire, une analyse de leurs relations réciproques et de leurs effets sur l'agriculture

    OpenAIRE

    Presuelou, Clio; Almeida, J.A. De J.

    1985-01-01

    Cet article montre l'importance du facteur "saison" dans l'analyse des problèmes alimentaires des pays en développement et dans la planification des actions appropriées. La relation entre la saisonalité et la pauvreté rurale a déjà fait l'objet d'une étude exploratoire (Chambers et al.). S'appuyant sur certaines de ces analyses et plus particulièrement sur la définition et les dimensions de la saisonalité, les auteurs examinent l'incidence de la saisonalité tropicale unimodale sur les agricul...

  5. Compte-rendu de la 3e conférence internationale sur les glucosinolates « Glucosinolates and beyond »

    Directory of Open Access Journals (Sweden)

    Quinsac Alain

    2015-01-01

    Full Text Available La 3e conférence internationale sur les glucosinolates, intitulée « Glucosinolates and beyond », a rassemblé plus d’une centaine de participants à Wageningen aux Pays-Bas, du 12 au 15 Octobre 2014. Le programme a été organisé en quatre sessions couvrant la recherche fondamentale sur l’origine et la biosynthèse des glucosinolates au cours de l’évolution, et les applications concrètes en santé humaine et agriculture. Près de 90 communications orales et posters, portant sur les récents progrès et les questions émergentes pour les recherches futures ont été présentés.

  6. Reducing the risk of iodine-based and MRI contrast media administration: Recommendation for a questionnaire at the time of booking

    DEFF Research Database (Denmark)

    Morcos, S.K.; Bellin, M.F.; Almen, T.

    2008-01-01

    This paper presents a practical questionnaire to be used when a contrast medium examination is requested. The questionnaire is based on the guidelines from the European Society of Urogenital Radiology. Its aim is to identify patients at increased risk of clinically relevant renal and non-renal ad......-renal adverse reactions to iodine-based and MRI contrast agents. The questionnaire should be completed by the referring physician when the examination is requested. (C) 2008 Elsevier Ireland Ltd. All rights reserved Udgivelsesdato: 2008/5......This paper presents a practical questionnaire to be used when a contrast medium examination is requested. The questionnaire is based on the guidelines from the European Society of Urogenital Radiology. Its aim is to identify patients at increased risk of clinically relevant renal and non...

  7. Second Colloquim on the Scattering of Ultrasonic Waves (Deuxieme Colloque sur la Diffusion des Ondes Ultrasonores).

    Science.gov (United States)

    1985-01-29

    8217 eau , Huiti me colloque sur le traitement du signal et ses applications (GRETSI), Nice, 1-5 June 1981, p. 637-644. [16] G. Maze, B. Taconet, and J...December 1984, to appear as a special issue of Traitement du Signal, published by La Direction des Recherches, Etudes et Techniques, 26 blvd. Victor...submerged in water, Huiti~me collogue sur le traitement du signal et ses applications (GRETSI), Nice, 1-5 June 1981, p. 637-644. [19] G. Maze et J

  8. Geopolítica, economía y solidaridad internacional en la nueva cooperación Sur-Sur: el caso de la Venezuela bolivariana y petrocaribe Geopolitics, economy and international solidarity in the new South-South cooperation: the case of Bolivarian

    Directory of Open Access Journals (Sweden)

    Daniele BENZI

    2013-05-01

    Full Text Available En el presente artículo se muestra un panorama del esquema de cooperación energética propuesto en 2005 por la República Bolivariana de Venezuela a los países centroamericanos y caribeños denominado PETROCARIBE. Se plantea que la emergencia de esta propuesta, al igual que otras iniciativas de cooperación Sur-Sur, está claramente vinculada a objetivos estratégicos de política exterior que remiten básicamente a parámetros geopolíticos, económicos, de seguridad y, por último, de solidaridad internacional. En la primera sección se reseñan algunas de las características, debates y principales tendencias de la cooperación Sur-Sur. Se presentan a continuación los rasgos específicos de la política exterior y energética bolivariana. Se ofrece sucesivamente una descripción general de la estructura, mecanismos de funcionamiento y principales proyectos en marcha de PETROCARIBE. Finalmente, tras discutir esta experiencia de cooperación Sur-Sur a la luz de sus alcances, problemas y vulnerabilidades, se esbozan algunas conclusiones.This article aims to show an overview of the energy cooperation scheme called PETROCARIBE, proposed in 2005 by the Bolivarian Republic of Venezuela to the Caribbean and Central American countries. It argues that the emergence of this project, like other South-South cooperation initiatives, is clearly linked to several strategic foreign policy goals, which basically refer to geopolitical, economic, security and, last but not least, international solidarity parameters. The first section outlines some general characteristics of South-South cooperation and current trends and debates. The following presents the peculiar features of the Bolivarian foreign and energy policies. The next presents a general description of the PETROCARIBE framework, working mechanisms and its most important projects. Finally, after a discussion on PETROCARIBE as a South-South cooperation initiative, by highlighting its scopes, problems

  9. sur la productivité des poulettes Effects o

    African Journals Online (AJOL)

    Au Burkina Faso, le facteur limitant dans l'alimentation des volailles est la protéine. Une étude a été menée en vue d'évaluer les effets d'une ration contenant la variété de maïs jaune « Espoir » sur les performances de croissance et de ponte chez les poulettes. Une ration contenant la variété de maïs. Espoir (ESPOIR) et ...

  10. IMPACT DE TROIS METHODES DE CONSERVATION SUR LES ...

    African Journals Online (AJOL)

    Administrateur

    bidons stérilisés sans chaux a permis d'avoir, après 8 mois de conservation, des taux de germination de. 85 et 86 %, respectivement au .... d'harmattan et battus le quatrième jour pour l'égrenage. Les semences ainsi obtenues ont été étalées en mince couches sur des claies placées sous abris. Elles y ont été séchées en.

  11. 118 Variabilité climatique et son incidence sur les ressources en ...

    African Journals Online (AJOL)

    MARTINE

    particulièrement fortes et touchent de nombreux secteurs d'activité. Le changement ... économique était basé sur l'agriculture est très sensible au contexte climatique [8,9]. ..... rupture. 3-2-6 Calcul du coefficient de tarissement : loi de Maillet.

  12. Impacts des caractéristiques physico-chimiques des eaux sur la ...

    African Journals Online (AJOL)

    Mart.) and Panicum maximum (Jacq.). Water Resources and Industry, 16: 1-18. https://doi.org/10.1016/j.wri.2016.07.001. Priso RJ, Dibong SD, Tchinda-Metagne C,. Taffouo VD, Ndongo D, Amougou A. 2010. Impacts des eaux polluées sur la.

  13. Impacts des caractéristiques physico-chimiques des eaux sur la ...

    African Journals Online (AJOL)

    Impacts des caractéristiques physico-chimiques des eaux sur la distribution du ... chimiques qui sont à l'origine d'une dégradation croissante de la qualité d'eau. ... Les valeurs d'indice de diversité de Shannon Weaver traduisent une grande ...

  14. An Improved Image Contrast Assessment Method

    Directory of Open Access Journals (Sweden)

    Yuanyuan Fan

    2013-07-01

    Full Text Available Contrast is an important factor affecting the image quality. In order to overcome the problems of local band-limited contrast, a novel image contrast assessment method based on the property of HVS is proposed. Firstly, the image by low-pass filter is performed fast wavelet decomposition. Secondly, all levels of band-pass filtered image and its corresponding low-pass filtered image are obtained by processing wavelet coefficients. Thirdly, local band-limited contrast is calculated, and the local band-limited contrast entropy is calculated according to the definition of entropy, Finally, the contrast entropy of image is obtained by averaging the local band-limited contrast entropy weighed using CSF coefficient. The experiment results show that the best contrast image can be accurately identified in the sequence images obtained by adjusting the exposure time and stretching gray respectively, the assessment results accord with human visual characteristics and make up the lack of local band-limited contrast.

  15. Simultaneous acquisition of dual analyser-based phase contrast X-ray images for small animal imaging

    International Nuclear Information System (INIS)

    Kitchen, Marcus J.; Pavlov, Konstantin M.; Hooper, Stuart B.; Vine, David J.; Siu, Karen K.W.; Wallace, Megan J.; Siew, Melissa L.L.; Yagi, Naoto; Uesugi, Kentaro; Lewis, Rob A.

    2008-01-01

    Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries between tissues. The phase and absorption information can be extracted by processing multiple images acquired at different analyser orientations. Recording both the transmitted and diffracted beams from a thin Laue analyser crystal can make phase retrieval possible for dynamic systems by allowing full field imaging. This technique was used to image the thorax of a mechanically ventilated newborn rabbit pup using a 25 keV beam from the SPring-8 synchrotron radiation facility. The diffracted image was produced from the (1 1 1) planes of a 50 mm x 40 mm, 100 μm thick Si analyser crystal in the Laue geometry. The beam and analyser were large enough to image the entire chest, making it possible to observe changes in anatomy with high contrast and spatial resolution

  16. Simultaneous acquisition of dual analyser-based phase contrast X-ray images for small animal imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kitchen, Marcus J. [School of Physics, Monash University, Victoria 3800 (Australia)], E-mail: Marcus.Kitchen@sci.monash.edu.au; Pavlov, Konstantin M. [School of Physics, Monash University, Victoria 3800 (Australia); Monash Centre for Synchrotron Science, Monash University, Victoria 3800 (Australia); Physics and Electronics, School of Science and Technology, University of New England, NSW 2351 (Australia)], E-mail: Konstantin.Pavlov@sci.monash.edu.au; Hooper, Stuart B. [Department of Physiology, Monash University, Victoria 3800 (Australia)], E-mail: Stuart.Hooper@med.monash.edu.au; Vine, David J. [School of Physics, Monash University, Victoria 3800 (Australia)], E-mail: David.Vine@sci.monash.edu.au; Siu, Karen K.W. [School of Physics, Monash University, Victoria 3800 (Australia); Monash Centre for Synchrotron Science, Monash University, Victoria 3800 (Australia)], E-mail: Karen.Siu@sci.monash.edu.au; Wallace, Megan J. [Department of Physiology, Monash University, Victoria 3800 (Australia)], E-mail: Megan.Wallace@med.monash.edu.au; Siew, Melissa L.L. [Department of Physiology, Monash University, Victoria 3800 (Australia)], E-mail: Melissa.Siew@med.monash.edu.au; Yagi, Naoto [SPring-8/JASRI, Sayo (Japan)], E-mail: yagi@spring8.or.jp; Uesugi, Kentaro [SPring-8/JASRI, Sayo (Japan)], E-mail: ueken@spring8.or.jp; Lewis, Rob A. [School of Physics, Monash University, Victoria 3800 (Australia); Monash Centre for Synchrotron Science, Monash University, Victoria 3800 (Australia)], E-mail: Rob.Lewis@sync.monash.edu.au

    2008-12-15

    Analyser-based phase contrast X-ray imaging can provide high-contrast images of biological tissues with exquisite sensitivity to the boundaries between tissues. The phase and absorption information can be extracted by processing multiple images acquired at different analyser orientations. Recording both the transmitted and diffracted beams from a thin Laue analyser crystal can make phase retrieval possible for dynamic systems by allowing full field imaging. This technique was used to image the thorax of a mechanically ventilated newborn rabbit pup using a 25 keV beam from the SPring-8 synchrotron radiation facility. The diffracted image was produced from the (1 1 1) planes of a 50 mm x 40 mm, 100 {mu}m thick Si analyser crystal in the Laue geometry. The beam and analyser were large enough to image the entire chest, making it possible to observe changes in anatomy with high contrast and spatial resolution.

  17. Connaissances et attitudes des manipulateurs radio du Togo sur l ...

    African Journals Online (AJOL)

    Objectif : Evaluer les connaissances et les attitudes des manipulateurs togolais sur l'irradiation médicale des grossesses. Matériels et Méthode : Etude transversale menée en Avril 2011 chez 72 manipulateurs de radiologie des structures sanitaires publiques et privées du Togo. Résultats : Le quart des manipulateurs ...

  18. Etude de la structure interne du nucleon en diffusion profondement inelastique de muons sur cibles fixes.

    CERN Document Server

    Granier, Thierry

    Dans ce mémoire est présentée l'analyse, dans le but de l'extraction des fonctions de structure, d'une partie des données de diffusion profondément inélastique de muons sur cibles fixes d'hydrogène et de detérium obtenues dans l'expérience NMC (New Muon Collaboration) du CERN. Les fonctions de structure, à partir desquelles s'exprime la probabilité de diffusion à un certain angle et une certaine énergie, contiennent de l'information sur la structure interne du nucléon, plus précisément sur la distribution en énergie des quarks à l'intérieur de celui-ci. L'étude de la variation des fonctions de structure avec le degré d'inélasticité de la diffusion permet de tester la validité de la chromodynamique quantique, la théorie de jauge des interactions fortes

  19. ESSAI D’EVALUATION DU STOCK DE GÉNITEURS D’ALOSE ALOSA ALOSA DU BASSIN VERSANT GIRONDE-GARONNE-DORDOGNE SUR LA PERIODE 1987-2001 ET COMPARAISON DE DIFFERENTS INDICATEURS D’ABONDANCE

    Directory of Open Access Journals (Sweden)

    CHANSEAU M.

    2004-04-01

    migratoires. Des mesures de la température de l’eau au niveau de la confluence Garonne-Dordogne seraient fort utiles et permettraient d’appréhender plus précisément l’influence des facteurs environnementaux sur cette répartition. Une augmentation de la proportion de poissons empruntant le cours d’eau Dordogne semble se dessiner ces dernières années puisque 44 % en moyenne des géniteurs sont remontés sur cet axe sur la période 1993-2001 contre 25 % en moyenne sur la période 1987-1992. Le stock reproducteur (stations de contrôle + frayères paraît être globalement un bon indicateur d’abondance de l’alose vraie sur le bassin en raison notamment de la relative stabilité des mortalités par pêche sur la période d’étude. Les CPUE issues du suivi de la pêcherie sont significativement reliées au stock total ainsi qu’aux effectifs estimés remontant sur les deux axes migratoires, indiquant qu’elles sont également un bon indicateur de l’abondance de l’alose. Elles ne sont toutefois pas à même de réellement refléter l’état du stock reproducteur et son évolution, bases de gestion de la population.

  20. Gadolinium-containing contrast media for radiographic examinations: a position paper

    International Nuclear Information System (INIS)

    Thomsen, Henrik S.; Almen, Torsten; Morcos, Sameh K.

    2002-01-01

    Recently, it has been suggested that gadolinium-based contrast media could be used for radiological examinations in patients with significant renal impairment, previous severe generalized reaction to iodinated contrast media or thyroid disease about to undergo radioactive iodine treatment; however, the indications for and risks of using gadolinium agents in this way are not well known; hence, the Contrast Media Safety Committee of The European Society of Urogenital Radiology reviewed the literature to issue a position paper on this subject. A comprehensive literature review was performed and the resulting report was discussed at the Ninth European Symposium on Urogenital Radiology in Genoa, Italy, June 2002. Review of the literature indicates that according to experimental data on animals gadolinium-based contrast media have more nephrotoxic potential than iodinated contrast media in equivalent X-ray attenuating doses; therefore, gadolinium-based contrast media should not replace iodinated contrast media in patients with renal insufficiency for radiographic examinations. For patients with previous severe generalized reactions to iodinated contrast media, and in patients about to undergo thyroid treatment with radioactive iodine gadolinium-based contrast media in approved intravenous doses, up to 0.3 mmol/kg body weight will not give diagnostic radiographic information in most cases. Gadolinium-based contrast media are not approved for radiographic examinations. (orig.)

  1. Safety of MR liver specific contrast media

    Energy Technology Data Exchange (ETDEWEB)

    Bellin, Marie-France [Hopital Paul Brousse, Universite Paris 11, Villejuif Cedex (France); Webb, Judith A.W. [St. Bartholomew' s Hospital, Department of Diagnostic Imaging, London (United Kingdom); Molen, Aart J. van der [Leiden University Medical Centre, Department of Radiology, Leiden (Netherlands); Thomsen, Henrik S. [Copenhagen University Hospital at Herlev, Department of Diagnostic Radiology 54E2, Herlev (Denmark); Morcos, Sameh K. [Northern General Hospital, Sheffield Teaching Hospitals NHS Trust, Department of Diagnostic Imaging, Sheffield (United Kingdom)

    2005-08-01

    Over the past few years a number of magnetic resonance (MR) liver specific contrast agents have been introduced. In this report the safety issues of these agents are addressed. A literature search was carried out. Based on the available information, simple guidelines on the safety issue of liver specific contrast agents have been produced by the Contrast Media Safety Committee of the European Society of Urogenital Radiology. The report and guidelines were discussed at the 11th European Symposium on Urogenital Radiology in Santiago de Compostela. Liver specific contrast agents appear in general to be safe and well tolerated. However, the incidence of adverse reactions with iron oxides and the intravenous manganese based agent seems to be slightly higher than with gadolinium based agents. However, no safety information from comparative clinical trials has been published. Guidelines on the safety aspects are presented. (orig.)

  2. Safety of MR liver specific contrast media

    International Nuclear Information System (INIS)

    Bellin, Marie-France; Webb, Judith A.W.; Molen, Aart J. van der; Thomsen, Henrik S.; Morcos, Sameh K.

    2005-01-01

    Over the past few years a number of magnetic resonance (MR) liver specific contrast agents have been introduced. In this report the safety issues of these agents are addressed. A literature search was carried out. Based on the available information, simple guidelines on the safety issue of liver specific contrast agents have been produced by the Contrast Media Safety Committee of the European Society of Urogenital Radiology. The report and guidelines were discussed at the 11th European Symposium on Urogenital Radiology in Santiago de Compostela. Liver specific contrast agents appear in general to be safe and well tolerated. However, the incidence of adverse reactions with iron oxides and the intravenous manganese based agent seems to be slightly higher than with gadolinium based agents. However, no safety information from comparative clinical trials has been published. Guidelines on the safety aspects are presented. (orig.)

  3. Predicting IDH mutation status of intrahepatic cholangiocarcinomas based on contrast-enhanced CT features

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Yong [Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Department of Radiology, Nanjing, Jiangsu Province (China); Chen, Jun [Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Department of Pathology, Nanjing, Jiangsu Province (China); Kong, Weiwei [Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Department of Oncology, Nanjing, Jiangsu Province (China); Mao, Liang; Qiu, Yudong [Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Department of Hepatopancreatobiliary Surgery, Nanjing, Jiangsu Province (China); Kong, Wentao [Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Department of Ultrasonography, Nanjing, Jiangsu Province (China); Zhou, Qun [Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Department of Radiology, Nanjing, Jiangsu Province (China); Zhou, Zhengyang; Zhu, Bin; He, Jian [Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Department of Radiology, Nanjing, Jiangsu Province (China); Wang, Zhongqiu [Jiangsu Province Hospital of Traditional Chinese Medicine, the Affiliated Hospital of Nanjing University of Chinese Medicine, Department of Radiology, Nanjing, Jiangsu Province (China)

    2018-01-15

    To explore the difference in contrast-enhanced computed tomography (CT) features of intrahepatic cholangiocarcinomas (ICCs) with different isocitrate dehydrogenase (IDH) mutation status. Clinicopathological and contrast-enhanced CT features of 78 patients with 78 ICCs were retrospectively analysed and compared based on IDH mutation status. There were 11 ICCs with IDH mutation (11/78, 14.1%) and 67 ICCs without IDH mutation (67/78, 85.9%). IDH-mutated ICCs showed intratumoral artery more often than IDH-wild ICCs (p = 0.023). Most ICCs with IDH mutation showed rim and internal enhancement (10/11, 90.9%), while ICCs without IDH mutation often appeared diffuse (26/67, 38.8%) or with no enhancement (4/67, 6.0%) in the arterial phase (p = 0.009). IDH-mutated ICCs showed significantly higher CT values, enhancement degrees and enhancement ratios in arterial and portal venous phases than IDH-wild ICCs (all p < 0.05). The CT value of tumours in the portal venous phase performed best in distinguishing ICCs with and without IDH mutation, with an area under the curve of 0.798 (p = 0.002). ICCs with and without IDH mutation differed significantly in arterial enhancement mode, and the tumour enhancement degree on multiphase contrast-enhanced CT was helpful in predicting IDH mutation status. (orig.)

  4. Improved tumor-targeting MRI contrast agents: Gd(DOTA) conjugates of a cycloalkane-based RGD peptide

    International Nuclear Information System (INIS)

    Park, Ji-Ae; Lee, Yong Jin; Ko, In Ok; Kim, Tae-Jeong; Chang, Yongmin; Lim, Sang Moo; Kim, Kyeong Min; Kim, Jung Young

    2014-01-01

    Highlights: • Development of improved tumor-targeting MRI contrast agents. • To increase the targeting ability of RGD, we developed cycloalkane-based RGD peptides. • Gd(DOTA) conjugates of cycloalkane-based RGD peptide show improved tumor signal enhancement in vivo MR images. - Abstract: Two new MRI contrast agents, Gd-DOTA-c(RGD-ACP-K) (1) and Gd-DOTA-c(RGD-ACH-K) (2), which were designed by incorporating aminocyclopentane (ACP)- or aminocyclohexane (ACH)-carboxylic acid into Gd-DOTA (gadolinium-tetraazacyclo dodecanetetraacetic acid) and cyclic RGDK peptides, were synthesized and evaluated for tumor-targeting ability in vitro and in vivo. Binding affinity studies showed that both 1 and 2 exhibited higher affinity for integrin receptors than cyclic RGDyK peptides, which were used as a reference. These complexes showed high relaxivity and good stability in human serum and have the potential to improve target-specific signal enhancement in vivo MR images

  5. Improved tumor-targeting MRI contrast agents: Gd(DOTA) conjugates of a cycloalkane-based RGD peptide

    Energy Technology Data Exchange (ETDEWEB)

    Park, Ji-Ae, E-mail: jpark@kirams.re.kr [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Lee, Yong Jin; Ko, In Ok [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Tae-Jeong; Chang, Yongmin [Institute of Biomedical Engineering, Kyungpook National University, Daegu (Korea, Republic of); Lim, Sang Moo [Department of Nuclear Medicine, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Kyeong Min [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Jung Young, E-mail: jykim@kirams.re.kr [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)

    2014-12-12

    Highlights: • Development of improved tumor-targeting MRI contrast agents. • To increase the targeting ability of RGD, we developed cycloalkane-based RGD peptides. • Gd(DOTA) conjugates of cycloalkane-based RGD peptide show improved tumor signal enhancement in vivo MR images. - Abstract: Two new MRI contrast agents, Gd-DOTA-c(RGD-ACP-K) (1) and Gd-DOTA-c(RGD-ACH-K) (2), which were designed by incorporating aminocyclopentane (ACP)- or aminocyclohexane (ACH)-carboxylic acid into Gd-DOTA (gadolinium-tetraazacyclo dodecanetetraacetic acid) and cyclic RGDK peptides, were synthesized and evaluated for tumor-targeting ability in vitro and in vivo. Binding affinity studies showed that both 1 and 2 exhibited higher affinity for integrin receptors than cyclic RGDyK peptides, which were used as a reference. These complexes showed high relaxivity and good stability in human serum and have the potential to improve target-specific signal enhancement in vivo MR images.

  6. Grating-based X-ray phase-contrast tomography of atherosclerotic plaque at high photon energies

    Energy Technology Data Exchange (ETDEWEB)

    Hetterich, Holger; Fill, Sandra [Klinikum der Ludwig-Maximilians-Univ., Muenchen (Germany). Inst. fuer Klinische Radiologie; Herzen, Julia [Technische Univ. Muenchen, Garching (Germany). Physik-Dept. und Inst. fuer Medizintechnik; Helmholtz-Zentrum Geesthacht, Geesthacht (Germany). Zentrum fuer Materialforschung] [and others

    2013-10-01

    Background: Tissue characterization of atherosclerosis by absorption-based imaging methods is limited due to low soft-tissue contrast. Grating-based phase-contrast computed tomography (PC-CT) may become an alternative for plaque assessment if the phase signal can be retrieved at clinically applicable photon energies. The aims of this feasibility study were (i) to characterize arterial vessels at low and high photon energies, (ii) to extract qualitative features and (iii) quantitative phase-contrast Hounsfield units (HU-phase) of plaque components at 53 keV using histopathology as gold standard. Materials and methods: Five human carotid artery specimens underwent grating-based PC-CT using synchrotron radiation of either 23 keV or 53 keV and histological work-up. Specimens without advanced atherosclerosis were used to extract signal criteria of vessel layers. Diseased specimens were screened for important plaque components including fibrous tissue (FT), lipid (LIP), necrotic core (NEC), intraplaque hemorrhage (IPH), inflammatory cell infiltration (INF) and calcifications (CA). Qualitative features as well as quantitative HU-phase were analyzed. Results: Thirty-three regions in 6 corresponding PC-CT scans and histology sections were identified. Healthy samples had the same signal characteristics at 23 keV and 53 keV with bright tunica intima and adventitia and dark media. Plaque components showed differences in signal intensity and texture at 53 keV. Quantitative analysis demonstrated the highest HU-phase of soft plaque in dense FT. Less organized LIP, NEC and INF were associated with lower HU-phase values. The highest HU-phase were measured in CA. Conclusion: PC-CT of atherosclerosis is feasible at high, clinically relevant photon energies and provides detailed information about plaque structure including features of high risk vulnerable plaques. (orig.)

  7. Le point sur les indices du bien-être national | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    21 janv. 2011 ... Aujourd'hui, de nouveaux indices perfectionnés tracent un portrait plus fouillé de l'état ... des progrès sur le plan économique, mais beaucoup de citoyens ne profitent pas de .... Tobacco Marketing — It's All Smoke and Mirrors.

  8. La recherche sur les montagnes entre Alpes et monde : regards rétrospectifs

    Directory of Open Access Journals (Sweden)

    Thomas Scheurer

    2009-03-01

    Full Text Available L’expression « recherche alpine », on le constatera au fil de ce volume, reste bien incertaine. La première lecture suscite une interrogation : s’agit-il d’une recherche menée sur les Alpes ou dans les Alpes ? Ou pour les Alpes ? C’est-à-dire répondant à une demande émanant d’« acteurs alpins » ? On observera aisément que la recherche sur des terrains alpins et selon des thématiques et des questionnements soulevés par les sociétés alpines est menée préférentiellement au sein des Alpes. Il n’y...

  9. Quantitative contrast-enhanced mammography for contrast medium kinetics studies

    Science.gov (United States)

    Arvanitis, C. D.; Speller, R.

    2009-10-01

    Quantitative contrast-enhanced mammography, based on a dual-energy approach, aims to extract quantitative and temporal information of the tumour enhancement after administration of iodinated vascular contrast media. Simulations using analytical expressions and optimization of critical parameters essential for the development of quantitative contrast-enhanced mammography are presented. The procedure has been experimentally evaluated using a tissue-equivalent phantom and an amorphous silicon active matrix flat panel imager. The x-ray beams were produced by a tungsten target tube and spectrally shaped using readily available materials. Measurement of iodine projected thickness in mg cm-2 has been performed. The effect of beam hardening does not introduce nonlinearities in the measurement of iodine projected thickness for values of thicknesses found in clinical investigations. However, scattered radiation introduces significant deviations from slope equal to unity when compared with the actual iodine projected thickness. Scatter correction before the analysis of the dual-energy images provides accurate iodine projected thickness measurements. At 10% of the exposure used in clinical mammography, signal-to-noise ratios in excess of 5 were achieved for iodine projected thicknesses less than 3 mg cm-2 within a 4 cm thick phantom. For the extraction of temporal information, a limited number of low-dose images were used with the phantom incorporating a flow of iodinated contrast medium. The results suggest that spatial and temporal information of iodinated contrast media can be used to indirectly measure the tumour microvessel density and determine its uptake and washout from breast tumours. The proposed method can significantly improve tumour detection in dense breasts. Its application to perform in situ x-ray biopsy and assessment of the oncolytic effect of anticancer agents is foreseeable.

  10. Computational cell quantification in the human brain tissues based on hard x-ray phase-contrast tomograms

    Science.gov (United States)

    Hieber, Simone E.; Bikis, Christos; Khimchenko, Anna; Schulz, Georg; Deyhle, Hans; Thalmann, Peter; Chicherova, Natalia; Rack, Alexander; Zdora, Marie-Christine; Zanette, Irene; Schweighauser, Gabriel; Hench, Jürgen; Müller, Bert

    2016-10-01

    Cell visualization and counting plays a crucial role in biological and medical research including the study of neurodegenerative diseases. The neuronal cell loss is typically determined to measure the extent of the disease. Its characterization is challenging because the cell density and size already differs by more than three orders of magnitude in a healthy cerebellum. Cell visualization is commonly performed by histology and fluorescence microscopy. These techniques are limited to resolve complex microstructures in the third dimension. Phase- contrast tomography has been proven to provide sufficient contrast in the three-dimensional imaging of soft tissue down to the cell level and, therefore, offers the basis for the three-dimensional segmentation. Within this context, a human cerebellum sample was embedded in paraffin and measured in local phase-contrast mode at the beamline ID19 (ESRF, Grenoble, France) and the Diamond Manchester Imaging Branchline I13-2 (Diamond Light Source, Didcot, UK). After the application of Frangi-based filtering the data showed sufficient contrast to automatically identify the Purkinje cells and to quantify their density to 177 cells per mm3 within the volume of interest. Moreover, brain layers were segmented in a region of interest based on edge detection. Subsequently performed histological analysis validated the presence of the cells, which required a mapping from the two- dimensional histological slices to the three-dimensional tomogram. The methodology can also be applied to further tissue types and shows potential for the computational tissue analysis in health and disease.

  11. Cancer mortality in the commune of Pargny sur Saulx in France

    International Nuclear Information System (INIS)

    Vathaire, F. de; Mollie, A.; Challeton de Vathaire, C.; Ropers, J.

    1998-01-01

    Radioactive thorium wastes were found in April 1997 at the former industrial site of 'Orflam-Plast' in the commune of Pargny sur Saulx in the Northeast of France, where industrial activity began in 1934. On this site, between 1934 and 1970, cerium for lighter stones and thorium nitrate were extracted from imported monazite sand, a mineral containing elevated levels of natural radioactivity. We decided to study cancer mortality in the surrounding population. We found an excess of mortality due to lung and bladder cancer in the commune of Pargny sur Saulx and its neighbours, between 1968 and 1994. This excess did not seem to be linked to the river of Saulx which was a possible source of contamination. We conclude that a cancer incidence study of the former workers of this industrial site is necessary in order to investigate the role of natural radioactivity from monazite processing in the risk of cancer mortality among this workforce. (author)

  12. Survey of effective doses to patients undergoing contrast-based X-ray fluoroscopy procedures in Tanzania

    International Nuclear Information System (INIS)

    Ngaile, J.E.; Msaki, P.K.; Kazema, R.R.

    2017-01-01

    The aim of this study was to assess the radiation burden imparted to patients from contrast-based X-ray fluoroscopy procedures in Tanzania. The effective doses (EDs) to patients from five contrast-based fluoroscopy procedures were obtained from four hospitals. The ED was estimated using the knowledge of the patient characteristics, patient-related exposure parameters, measurements of air kerma area product and PCXCM software. The median EDs for the barium swallow (BS), barium meal (BM), barium enema (BE), hysterosalpingography (HSG) and retrograde urethrography (RUG) were 0.50, 1.43, 2.83, 0.65 and 0.59 mSv, respectively. The median ED per hospital for the BS and BM procedures varied by factors of up to 9.9 and 4.2, respectively, while for the BE, HSG and RUG varied by factors of up to 2.3, 2.4 and 4.3, respectively. The overall differences between individual EDs across the four hospitals varied by factors of up to 53, 58.9 and 11.4 for the BS, BM and BE, respectively, while for the HSG and RUG differed by factors of up to 22 and 46.7, respectively. The mean EDs in this study were mostly lower than reported values from Spain, the UK, Ghana and Greece, while slightly higher than those reported from India. The observed wide variations of procedural protocols and patient doses within and across the hospitals; and the observed high patient doses in this study relative to those from the literature call for the need to standardize procedural protocols and optimize contrast-based fluoroscopy procedures. (authors)

  13. Professorat de recherche sur les droits de la personne reconnus ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Pour ce projet, le CRDI s'associe à la Norman Paterson School of International Affairs (NPSIA) pour réaliser un programme de recherche portant sur les droits de la personne reconnus internationalement. La subvention servira à payer pendant deux ans la moitié du salaire et des avantages sociaux du professeur agrégé ...

  14. Migración sur-sur: factores relacionales e inserción segmentada de la población boliviana y peruana en la ciudad de Córdoba, Argentina

    Directory of Open Access Journals (Sweden)

    Eduardo León Bologna

    2016-01-01

    Full Text Available Como caso de migración sur-sur se analizan las poblaciones de origen boliviano y peruano residentes en la ciudad de Córdoba, con la hipótesis del mayor peso explicativo de factores relacionales respecto de las diferencias de desarrollo entre las regiones de origen y destino. Se comparan la estructura demográfica, la inserción educativa y la distribución espacial de las dos poblaciones entre los censos nacionales de 2001 y 2010. Por razones de disponibilidad de los datos la inserción ocupacional sólo se describe en el censo de 2001, y a través de los antecedentes por medio de encuestas para el periodo siguiente. Se concluye que el atractivo de Córdoba se debe más a los vínculos históricos que estos dos colectivos migrantes han forjado con la ciudad que al nivel de desarrollo económico o social de ésta.

  15. Sur quelques espèces du genre Scarabaeus L

    NARCIS (Netherlands)

    Gillet, Joseph J.E.

    1909-01-01

    Dans une note insérée aux Annali del Museo Civico di storia naturale di Genova ¹), je rue suis occupé, entre autres choses, de la synonymie de quelques espèces de Scarabaeus; je désire revenir sur ce sujet et y ajouter les remarques que m’a suggérées l’examen du type de S. van der Kelleni LSBG. et

  16. Reducing the risk of iodine-based and MRI contrast media administration: Recommendation for a questionnaire at the time of booking

    International Nuclear Information System (INIS)

    Morcos, Sameh K.; Bellin, Marie-France; Thomsen, Henrik S.; Almen, Torsten; Aspelin, Peter; Heinz-Peer, Gertraud; Jakobsen, Jarl A.; Liss, Per; Oyen, Raymond; Stacul, Fulvio; Molen, Aart J. van der; Webb, Judith A.W.

    2008-01-01

    This paper presents a practical questionnaire to be used when a contrast medium examination is requested. The questionnaire is based on the guidelines from the European Society of Urogenital Radiology. Its aim is to identify patients at increased risk of clinically relevant renal and non-renal adverse reactions to iodine-based and MRI contrast agents. The questionnaire should be completed by the referring physician when the examination is requested

  17. Reducing the risk of iodine-based and MRI contrast media administration: Recommendation for a questionnaire at the time of booking

    Energy Technology Data Exchange (ETDEWEB)

    Morcos, Sameh K. [Department of Diagn. Imaging, Northern General Hospital, Herries Road, Sheffield S5 7AU (United Kingdom)], E-mail: sameh.morcos@sth.nhs.uk; Bellin, Marie-France [Service de Radiologie, Hopital Paul Brousse, 14 Av. Paul Vaillant Couturier, F-94800 Villejuif (France)], E-mail: marie-france.bellin@pbr.ap-hop-paris.fr; Thomsen, Henrik S. [Department of Diagnostic Radiology 54E2, Copenhagen University Hospital Herlev, Herlev Ringvej 75, DK-2730 Herlev (Denmark)], E-mail: hentho01@heh.regionh.dk; Almen, Torsten [Lybska Vaegen 10, S-239 40 Falsterbo (Sweden)], E-mail: torsten.almen@ta-contrast.se; Aspelin, Peter [Diagnostic Radiology, Huddinge University Hospital, S-141 86 Huddinge (Sweden)], E-mail: peter.aspelin@ki.se; Heinz-Peer, Gertraud [Department of Radiology, University Hospital Vienna, AKH, Wahringer Gurtel 18-20, A-1090 Vienna (Austria)], E-mail: gertraud.heinz@meduniwien.ac.at; Jakobsen, Jarl A. [Department of Radiology, Rikshospitalet, N-0027 Oslo (Norway)], E-mail: jarl.jakobsen@rikshospitalet.no; Liss, Per [Department of Radiology, Akademiska sjukhuset, SE-751 85 Uppsala (Sweden)], E-mail: per.liss@akademiska.se; Oyen, Raymond [Department of Radiology, University Hospital Gasthuisberg, Herestraat 46, B-3000 Leuven (Belgium)], E-mail: raymond.oyen@uzleuven.be; Stacul, Fulvio [Institute of Radiology, Ospedale di Cattinara, I-34149 Trieste (Italy)], E-mail: fulvio.stacul@aots.sanita.fvg.it; Molen, Aart J. van der [Department of Radiology, C2-S, Leiden University Medical center, P.O. Box 9600, NL-2300 RC Leiden (Netherlands)], E-mail: aart.vdmolen@planet.nl; Webb, Judith A.W. [3 Sellars Hall Close, Finchley, London N3 1JL (United Kingdom)], E-mail: jawwebb@btopenworld.com

    2008-05-15

    This paper presents a practical questionnaire to be used when a contrast medium examination is requested. The questionnaire is based on the guidelines from the European Society of Urogenital Radiology. Its aim is to identify patients at increased risk of clinically relevant renal and non-renal adverse reactions to iodine-based and MRI contrast agents. The questionnaire should be completed by the referring physician when the examination is requested.

  18. The pointillism method for creating stimuli suitable for use in computer-based visual contrast sensitivity testing.

    Science.gov (United States)

    Turner, Travis H

    2005-03-30

    An increasingly large corpus of clinical and experimental neuropsychological research has demonstrated the utility of measuring visual contrast sensitivity. Unfortunately, existing means of measuring contrast sensitivity can be prohibitively expensive, difficult to standardize, or lack reliability. Additionally, most existing tests do not allow full control over important characteristics, such as off-angle rotations, waveform, contrast, and spatial frequency. Ideally, researchers could manipulate characteristics and display stimuli in a computerized task designed to meet experimental needs. Thus far, 256-bit color limitation in standard cathode ray tube (CRT) monitors has been preclusive. To this end, the pointillism method (PM) was developed. Using MATLAB software, stimuli are created based on both mathematical and stochastic components, such that differences in regional luminance values of the gradient field closely approximate the desired contrast. This paper describes the method and examines its performance in sine and square-wave image sets from a range of contrast values. Results suggest the utility of the method for most experimental applications. Weaknesses in the current version, the need for validation and reliability studies, and considerations regarding applications are discussed. Syntax for the program is provided in an appendix, and a version of the program independent of MATLAB is available from the author.

  19. El impacto del centro universitario de la costa sur en el municipio de Autlán de Navarro, Jalisco, México

    OpenAIRE

    Castañeda Palomera, Alfredo

    2015-01-01

    Con el objetivo de estimar el impacto económico, social y cultural del Centro Universitario de la Costa Sur (CU Costa Sur) en el Municipio de Autlán de la Navarro, Jalisco, México se realizó la presente tesis. Se fundamenta en la premisa de que el CU Costa Sur como una dependencia de la Universidad de Guadalajara maneja recursos económicos, empleo, incide en el desarrollo y crecimiento de empresas, en la formación de recursos humanos y el mejoramiento de las artes, la danza, el teatro y la cu...

  20. Les teneurs en carbone, azote et phosphore du sol sur l'occurrence ...

    African Journals Online (AJOL)

    Les teneurs en carbone, azote et phosphore du sol sur l'occurrence de Lippia multiflora M. (théier de savane) et la composition chimique de son huile essentielle extraite des feuilles au Nord-Ouest de la Côte d'Ivoire.

  1. Bourse de recherche postdoctorale sur l'Amérique centrale et les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    établir un poste de recherche postdoctorale sur l'Amérique centrale et les ... IDRC is pleased to announce a new funding opportunity aimed at fostering effective, long-term climate action to reduce social inequality, promote greater gender parity, ...

  2. Les effets des interfaces sur les proprietes magnetiques et de transport des multicouches nickel/iron et cobalt/silver

    Science.gov (United States)

    Veres, Teodor

    Cette these est consacree a l'etude de l'evolution structurale des proprietes magnetiques et de transport des multicouches Ni/Fe et nanostructures a base de Co et de l'Ag. Dans une premiere partie, essentiellement bibliographique, nous introduisons quelques concepts de base relies aux proprietes magnetiques et de transport des multicouches metalliques. Ensuite, nous presentons une breve description des methodes d'analyse des resultats. La deuxieme partie est consacree a l'etude des proprietes magnetiques et de transport des multicouches ferromagnetiques/ferromagnetiques Ni/Fe. Nous montrerons qu'une interpretation coherente de ces proprietes necessite la prise en consideration des effets des interfaces. Nous nous attacherons a mettre en evidence, a evaluer et a etudier les effets de ces interfaces ainsi que leur evolution, et ce, suite a des traitements thermiques tel que le depot a temperature elevee et l'irradiation ionique. Les analyses correlees de la structure et de la magnetoresistance nous permettront d'emettre des conclusions sur l'influence des couches tampons entre l'interface et le substrat ainsi qu'entre les couches elles-memes sur le comportement magnetique des couches F/F. La troisieme partie est consacree aux systemes a Magneto-Resistance Geante (MRG) a base de Co et Ag. Nous allons etudier l'evolution de la microstructure suite a l'irradiation avec des ions Si+ ayant une energie de 1 MeV, ainsi que les effets de ces changements sur le comportement magnetique. Cette partie debutera par l'analyse des proprietes d'une multicouche hybride, intermediaire entre les multicouches et les materiaux granulaires. Nous analyserons a l'aide des mesures de diffraction, de relaxation superparamagnetique et de magnetoresistance, les evolutions structurales produites par l'irradiation ionique. Nous etablirons des modeles qui nous aideront a interpreter les resultats pour une serie des multicouches qui couvrent un large eventail de differents comportements magnetiques

  3. MRI and CT contrast media extravasation

    Science.gov (United States)

    Heshmatzadeh Behzadi, Ashkan; Farooq, Zerwa; Newhouse, Jeffery H.; Prince, Martin R.

    2018-01-01

    Abstract Background: This systematic review combines data from multiple papers on contrast media extravasation to identify factors contributing to increased extravasation risk. Methods: Data were extracted from 17 papers reporting 2191 extravasations in 1,104,872 patients (0.2%) undergoing computed tomography (CT) or magnetic resonance imaging (MRI). Results: Extravasation rates were 0.045% for gadolinium-based contrast agents (GBCA) and nearly 6-fold higher, 0.26% for iodinated contrast agents. Factors associated with increased contrast media extravasations included: older age, female gender, using an existing intravenous (IV) instead of placing a new IV in radiology, in-patient status, use of automated power injection, high injection rates, catheter location, and failing to warm up the more viscous contrast media to body temperature. Conclusion: Contrast media extravasation is infrequent but nearly 6 times less frequent with GBCA for MRI compared with iodinated contrast used in CT. PMID:29489663

  4. LA CERÁMICA CERRO LOS HORNOS, PRESENCIA INKA EN LA COSTA DE TACNA, SUR DEL PERÚ

    OpenAIRE

    Vela Velarde, Carlos

    2004-01-01

    Se estudia el sitio Cerro Los Hornos, ubicado en la costa de Tacna, sur del Perú. Presenta cerámica con filiación Inka Imperial o Cuzco Policromo, pero de fabricación local; esta presencia cultural es consecuencia del proceso de expansión Inka a la costa sur del Perú, la cual establece relaciones con la sociedad local The place studied is Cerro Los Hornos located in the coast of Tacna, south of Peru, presents ceramic with filiation Inka Imperial or Cuzco Policromo, but of local production;...

  5. Les estimations du capital humain au Canada : approche fondee sur le revenu de la vie entiere

    OpenAIRE

    Gu, Wulong; Wong, Ambrose

    2010-01-01

    Dans le present document, nous produisons une estimation de l'investissement en capital humain fonde sur le marche et du stock de ce capital au Canada au cours de la periode s'etendant de 1970 a 2007 selon l'approche fondee sur le revenu de la vie entiere. Nous comparons cette estimation a celle de l'investissement en capital physique et naturel et du stock de ce capital. En suivant la methode elaboree par Jorgenson et Fraumeni, nous estimons le stock de capital humain sous forme du revenu de...

  6. Approche pour la recommandation de ressources pédagogiques basée sur les liens sociaux

    OpenAIRE

    Tadlaoui , Mohammed; George , Sébastien; Sehaba , Karim

    2015-01-01

    Conférence EIAH 2015; Les systèmes de recommandation ont pour objectif de proposer des ressources pertinentes à une personne en utilisant certaines informations sur les utilisateurs et les ressources du système. Notre travail s’intègre dans le contexte des systèmes de recommandation de ressources pédagogiques et plus particulièrement des systèmes qui utilisent des informations sociales. En se basant sur les résultats de recherche dans le domaine des systèmes de recommandation, des réseaux soc...

  7. Modelling air pollution transfers in the Fos-Sur-Mer area

    International Nuclear Information System (INIS)

    Dibi, Niagne Martin

    1985-01-01

    A 'puff' gaussian model with determined standard deviations based on transfer times of two classes of vertical stability of the atmosphere was developed in order to evaluate the atmospheric dispersion of industrial discharges in the Fos-sur-Mer area. This research was carried out within the framework of a large study for the processing of the data obtained during the measurement campaign organized by the European Communities. The model in its analytic form allows consideration of the main phenomena which modify the puff content during the transfer: reflectance, wet and dry deposition, physical-chemical transformation of the pollutant SO 2 . The model includes the site meteorological parameters measured in three dimensions (wind speed and direction at ground level and in altitude) and the characteristics of the different stacks. It can also calculate pollutions resulting from a short emission or from continuous emissions. Examples are presented. (author) [fr

  8. Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications

    International Nuclear Information System (INIS)

    Reimer, Peter; Schneider, Guenter; Schima, Wolfgang

    2004-01-01

    Hepatobiliary contrast agents with uptake into hepatocytes followed by variable biliary excretion represent a unique class of cell-specific MR contrast agents. Two hepatobiliary contrast agents, mangafodipir trisodium and gadobenate dimeglumine, are already clinically approved. A third hepatobiliary contrast agent, Gd-EOB-DTPA, is under consideration. The purpose of this review is to provide an overview on the properties, clinical development and application of these three hepatobiliary contrast agents. Bolus injectable paramagnetic hepatobiliary contrast agents combine established features of extracellular agents with the advantages of hepatocyte specificity. The detection and characterisation of focal liver disease appears to be improved compared to unenhanced MRI, MRI with unspecific contrast agents and contrast-enhanced CT. To decrease the total time spent by a patient in the MR scanner, it is advisable to administer the agent immediately after acquisition of unenhanced T1-w MRI. After infusion or bolus injection (with dynamic FS-T1-w 2D or 3D GRE) of the contrast agent, moderately and heavily T2w images are acquired. Post-contrast T1-w MRI is started upon completion of T2-w MRI for mangafodipir trisodium and Gd-EOB-DTPA as early as 20 min following injection, while gadobenate dimeglumine scans are obtained >60 min following injection. Post-contrast acquisition techniques with near isotropic 3D pulse sequences with fat saturation parallel the technical progress made by MSCT combined with an unparalleled improvement in tumour-liver contrast. The individual decision that hepatobiliary contrast agent one uses is partly based on personal preferences. No comparative studies have been conducted comparing the advantages or disadvantages of all three agents directly against each other. (orig.)

  9. Regards croisés sur l’action des ONG en éducation au Sud

    OpenAIRE

    Barlet, Sandra; Biache, Roland; Diouf, Mahfou; Dumont, Bernard; Gauron, André; Huguenin, Valérie; Marchand, Jacques; Migan, Gilbert

    2012-01-01

    Des représentants d’ONG, de bailleurs, d’un ministère au Sud et des experts sont interrogés sur les évolutions qui ont caractérisé l’action et le positionnement des ONG actives au Sud dans le champ de l’éducation depuis dix ans, et sur les nouveaux rôles qui se dessinent pour elles à l’horizon 2020. Plusieurs thèmes sont abordés : la mobilisation de la société civile et la gestion locale de l’éducation ; la conception du rôle de l’État et les besoins en intervention non gouvernementale ; le r...

  10. Comparison between computed tomography with oral oil-based contrast and laparotomy for gastric cancer staging; Tomografia computerizada con contraste oral graso frente a lapartomia en la estadificacion del cancer gastrico

    Energy Technology Data Exchange (ETDEWEB)

    Marco, S. F.; Garcia-Vila, J. H.; Cervera, J.; Gomez, R.; Piqueras, R. M.; Perona, I.; Escrig, J.; Salvador, J. L. [Hospital General de Castello. Castellon (Spain)

    2000-07-01

    To compare the utility of conventional computed tomography (CT) with oral oil-based contrast with that of laparotomy in the preoperative staging of gastric cancer. We prospectively studied 41 patients diagnosed as having gastric adenocarcinoma according to the results of endoscopy and biopsy. Applying the TNM classification for gastric cancer staging, we compared the findings in CT associated with oral oil-based contrast and intraoperative staging with definitive postoperative pathological staging. Definitive pathological studies demonstrated that there were 7 stage T1-T2 lesions, 26 stage T3 and 8 stage T4. The assessment of lymph node involvement showed that 10 patients presented stage N0 and 31 stage N1-N3. Ten patients had metastases. The diagnostic reliability for tumor staging according to CT was 56% versus 80% for laparotomy. In the determination of nodal involvement CT had a diagnostic yield of 71% versus 6% for laparotomy. Metastatic disease was correctly diagnosed by CT in 83% of cases versus 88% by laparotomy. There were no statistically significant differences between CT with oral oil-based contrast and laparotomy for the staging of nodal involvement and metastases. However, the CT diagnosis was significantly more reliable than laparotomy for the determination of tumor infiltration. (Author) 21 refs.

  11. Contrast agent based on nano-emulsion for targeted biomedical imaging

    International Nuclear Information System (INIS)

    Attia, Mohamed

    2016-01-01

    poly(maleic anhydride-alt-1-octadecene) (PMAO). The in vitro results and in vivo evaluations were completely coherent approving that the neutral charged NPs are less toxic compared to the negatively charged ones that were highly up-taken in the cells causing stress to the cells and thereby affecting the toxicity. As a result they are different in biodistribution and pharmacokinetics. In this context, for the first time, we were able to functionalize the nano-emulsion droplets with ligand molecules by covalent bonds. Likewise we designed nano-droplets and coated by silica shell ended by amino groups and then followed by formation of amide bonds with grafting to dye ligand model (coumarin blue dye). The quantification of amino groups was performed by using spectroscopic and microscopic techniques, with a grafting efficiency as high as 41%. This process improves the targeting properties of such chemotherapeutic agents to the location of interest following active targeting mechanism (ligand receptor strategy). One of our achieved objectives was to engineer multifunctional polymer-based NPs encapsulating hydrophobic drug model as DDs and iron oxide NPs as a theranostic model. To conclude, novel contrast agents and delivering systems were synthesized with outstanding physicochemical characteristics and suitable for in vivo medium with high efficacy and low toxicity [fr

  12. L’eau, l’écrit et la société. Étude statistique sur les champs sémantiques dans les bases de données [CBMA

    Directory of Open Access Journals (Sweden)

    Nicolas Perreaux

    2011-08-01

    Full Text Available Intitulé « L’eau, l’écrit et la société. Étude statistique sur les champs sémantiques dans les bases de données [CBMA] » , notre mémoire de master partait d’un constat relativement simple : les chartes, ces documents conservés plutôt en grande abondance, contiennent un nombre extrêmement important de termes relatifs à la description et donc, par extension, à la perception du monde par les médiévaux. Or, il est clair que ces formules, plus ou moins stéréotypées, n’ont presque jamais été consid...

  13. Extracellular gadolinium-based contrast media: Differences in diagnostic efficacy

    Energy Technology Data Exchange (ETDEWEB)

    Molen, Aart J. van der [Department of Radiology C-2S, Leiden University Medical Centre, Albinusdreef 2, NL-2333 ZA Leiden (Netherlands)], E-mail: molen@lumc.nl; Bellin, Marie-France [Universite Paris-Sud XI, AP-HP, Service de Radiologie, Hopital Paul Brousse, 12-14 Avenue Paul Vaillant Couturier, F-94804 Villejuif Cedex (France)

    2008-05-15

    Since the introduction of the first gadolinium-based contrast agent (Gd-CA) in 1988 it has become clear that these agents significantly improve the diagnostic efficacy of MRI. Studies on single agents have shown that, in comparison to unenhanced sequences, all agents help to improve the detection and delineation of lesions which can alter diagnosis in up to 40% of patients. Doubling or tripling the standard dose of 0.1 mmol/kg body weight may be beneficial for selected indications (e.g. brain perfusion, equivocal single dose study in MRI for brain metastasis, small vessel MR angiography). A more limited number of studies have compared the various agents. These studies do not show clinically significant differences in diagnostic efficacy between the various extracellular Gd-CA. Agents with higher concentration or protein binding may be relatively better suitable for selected applications (e.g. perfusion MRI). The higher relaxivity agents may be used in somewhat lower doses than the extracellular agents.

  14. Extracellular gadolinium-based contrast media: Differences in diagnostic efficacy

    International Nuclear Information System (INIS)

    Molen, Aart J. van der; Bellin, Marie-France

    2008-01-01

    Since the introduction of the first gadolinium-based contrast agent (Gd-CA) in 1988 it has become clear that these agents significantly improve the diagnostic efficacy of MRI. Studies on single agents have shown that, in comparison to unenhanced sequences, all agents help to improve the detection and delineation of lesions which can alter diagnosis in up to 40% of patients. Doubling or tripling the standard dose of 0.1 mmol/kg body weight may be beneficial for selected indications (e.g. brain perfusion, equivocal single dose study in MRI for brain metastasis, small vessel MR angiography). A more limited number of studies have compared the various agents. These studies do not show clinically significant differences in diagnostic efficacy between the various extracellular Gd-CA. Agents with higher concentration or protein binding may be relatively better suitable for selected applications (e.g. perfusion MRI). The higher relaxivity agents may be used in somewhat lower doses than the extracellular agents

  15. Recommandations stratégiques sur la décentralisation, le pouvoir ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    22 déc. 2010 ... Il découle des analyses et des témoignages présentés lors de la ... Recommandations stratégiques sur la décentralisation, le pouvoir local et les droits des femmes ... Réduire la violence urbaine : Pourquoi certains hommes ...

  16. Pouvoir pathogène de Botrytis cinerea sur Catharanthus roseus à ...

    African Journals Online (AJOL)

    SARAH

    38,53 et C.I=1274.41 pour BC1). Au 31ème ... Conclusion et application de la recherche : l'étude a montré le pouvoir pathogène de B. cinerea sur C. roseus à différents ..... 1977; Kosuge et Hewitt, 1964). Et permettent à des.

  17. Artificial Intelligence in the Petroleum World Une enquête sur les applications de l'Intelligence Artificielle dans le monde pétrolier

    Directory of Open Access Journals (Sweden)

    Braunschweig B. L.

    2006-11-01

    , bien que souvent de faible taille comparés à leurs équivalents dans d'autres branches de l'industrie (électricité, transport, aérospatiale, banque et finance, chimie, informatique. L'ensemble des questionnaires fournit un total de mille hommes-ans investis sur MA par les organisations interrogées. Ayant rencontré environ la moitié des intervenants du domaine géographique présenté plus haut, nous évaluons à 2-300 hommes-ans l'investissement total de l'industrie pétrolière sur des projets IA depuis dix ans, ce qui représente un budget de 2 à 3 milliards de francs 1990. Il est intéressant de mentionner que la deuxième vague de développement de systèmes à base de connaissances (que l'on commence à appeler systèmes experts de seconde génération semble s'accompagner d'une deuxième vague équivalente d'applications dans l'industrie pétrolière, non seulement en raison de ce saut méthodologique, mais aussi en relation avec la crise de la fin des années 80. Cette crise a eu des effets contrastés, ago-antagonistes, sur les équipes et les projets IA au sein des compagnies : certaines équipes furent supprimées ou fortement réduites en raison de la diminution des budgets de recherche, mais des projets démarrèrent en raison d'un nouveau besoin qui était d'exercer les mêmes activités (chercher, produire, raffiner du pétrole avec un personnel moins nombreux et moins expérimenté. Tant que le prix du baril restera proche de ou supérieur à 20 $, il y aura des gens, des machines et de l'argent disponibles pour mener des projets IA dans le monde pétrolier.

  18. Explicit vs. Contrastive-based Instruction of Formulaic Expressions in Developing EFL Learners’ Reading Ability

    Directory of Open Access Journals (Sweden)

    Gholam-Reza Abbasian

    2012-05-01

    Full Text Available As an integrative component of textual structure, formulaic expressions (FEs play a key role in communicating the message and comprehending the text. Furthermore, interlingually contrastive features of FEs add to their both significance and complexity of their instruction. Given these facts, this study was an attempt to explore a sound mechanism on how to teach FEs; whether an explicit or CA-based approach to FEs instruction could entail various achievements among EFL learners’ reading ability. To this end, three groups of Iranian EFL learners, identified as homogeneous based on Nelson Proficiency Test, were classified into one control and two experimental (i.e. explicit and CA-based instruction ones. They were exposed to conventional, explicit and CA-based instructions of a set of selected FEs developed into and presented in the form of an instructional handout. Their Knowledge of reading was also tested based on a researcher-made diagnostic test prior to the experiment. Both quantitative and qualitative paradigms were employed to measure both the achievements and the extent of contrast between Persian and English languages in terms of FEs. The former analysis revealed significance difference among the groups in terms of instruction type effectiveness; both explicit and CA-based instruction groups outperformed the control group; on the contrary, no statistically significant difference was revealed between the experimental groups. Additionally, the latter paradigm revealed differences and mismatches between Persian and English FEs in terms of semantic, syntactic and pragmatic parameters. The findings could be insightful for EFL instructors, learners, textbook writers, and syllabus designers to take into account issues like these in their pedagogical programs.

  19. SECTION 4 : BUDGET Remarque : Pour en savoir plus sur les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    (anonymous)

    SECTION 4 : BUDGET. Remarque : Pour en savoir plus sur les restrictions budgétaires, consulter l'appel à propositions et la foire aux questions. Inscrire toutes les sommes en dollars canadiens. 4.1 Indiquez toutes les dépenses prévues (en CAD). Inscrire une valeur numérique sans caractères, ni espaces, ni virgules (p. ex ...

  20. High Signal Intensity in the Dentate Nucleus and Globus Pallidus on Unenhanced T1-Weighted MR Images: Comparison between Gadobutrol and Linear Gadolinium-Based Contrast Agents.

    Science.gov (United States)

    Moser, F G; Watterson, C T; Weiss, S; Austin, M; Mirocha, J; Prasad, R; Wang, J

    2018-02-01

    In view of the recent observations that gadolinium deposits in brain tissue after intravenous injection, our aim of this study was to compare signal changes in the globus pallidus and dentate nucleus on unenhanced T1-weighted MR images in patients receiving serial doses of gadobutrol, a macrocyclic gadolinium-based contrast agent, with those seen in patients receiving linear gadolinium-based contrast agents. This was a retrospective analysis of on-site patients with brain tumors. Fifty-nine patients received only gadobutrol, and 60 patients received only linear gadolinium-based contrast agents. Linear gadolinium-based contrast agents included gadoversetamide, gadobenate dimeglumine, and gadodiamide. T1 signal intensity in the globus pallidus, dentate nucleus, and pons was measured on the precontrast portions of patients' first and seventh brain MRIs. Ratios of signal intensity comparing the globus pallidus with the pons (globus pallidus/pons) and dentate nucleus with the pons (dentate nucleus/pons) were calculated. Changes in the above signal intensity ratios were compared within the gadobutrol and linear agent groups, as well as between groups. The dentate nucleus/pons signal ratio increased in the linear gadolinium-based contrast agent group ( t = 4.215, P linear gadolinium-based contrast agent group ( t = 2.931, P linear gadolinium-based contrast agents. © 2018 by American Journal of Neuroradiology.

  1. Recherche d'informations sur Internet au collège et au lycée : méthode, commentaires et exemples

    OpenAIRE

    Beaufils, Alain

    2004-01-01

    Etude menée par l'INRP-Tecné (recherche 40123).; Dans deux établissements scolaires de la banlieue parisienne (collège et lycée), nous avons mené une observation sur quelques élèves volontaires de quatrième et de seconde. Leur tâche consistait à répondre à une question portant sur un thème assez large en utilisant des informations trouvées sur Internet et en limitant leur recherche aux documents rédigés en langue française. L'activité a eu lieu au CDI et comportait une séance d'entraînement s...

  2. Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque

    NARCIS (Netherlands)

    van Bochove, Glenda S.; Paulis, Leonie E. M.; Segers, Dolf; Mulder, Willem J. M.; Krams, Rob; Nicolay, Klaas; Strijkers, Gustav J.

    2011-01-01

    Interest in the use of contrast-enhanced MRI to enable in vivo specific characterization of atherosclerotic plaques is increasing. In this study the intrinsic ability of three differently sized gadolinium-based contrast agents to permeate different mouse plaque phenotypes was evaluated with MRI. A

  3. Effets potentiels d’un modèle rationnel de prescription sur les dépenses nationales en santé

    Science.gov (United States)

    Littman, Jordan; Halil, Roland

    2016-01-01

    Résumé Objectif Estimer les économies que pourrait engendrer la mise en œuvre d’un modèle rationnel de prescription pour des classes de médicaments équivalents sur les plans de l’efficacité, de la toxicité et de la commodité. Conception L’Institut canadien d’information sur la santé a fourni des renseignements sur les 10 principales classes de médicaments en fonction des dépenses annuelles qui leur sont attribuables. Ces classes ont été examinées en vue de leur inclusion potentielle dans l’étude selon qu’il était possible de comparer les médicaments à l’intérieur d’une même classe. Lorsqu’à la suite d’une recherche documentaire, une équivalence a été établie en fonction de l’efficacité, de la toxicité et de la commodité des médicaments, les données annuelles sur les prescriptions ont été recueillies à partir de la base de données du Système national d’information sur l’utilisation des médicaments prescrits. Les économies potentielles de coûts ont ensuite été calculées en comparant les parts de marché actuelles avec les parts potentielles futures de ce marché. Contexte Le Canada. Principaux paramètres à l’étude Les différences estimées dans les dépenses que produirait un modèle rationnel de prescription. Résultats Une équivalence a été établie sur les plans de l’efficacité, de la toxicité et de la commodité dans les classes de statines, d’inhibiteurs de la pompe à protons, d’inhibiteurs de l’enzyme de conversion de l’angiotensine et d’inhibiteurs sélectifs du recaptage de l’angiotensine. Les dépenses annuelles totales dans ces classes se situent à 856 millions $ dans les programmes publics de médicaments et à 1,97 milliard $ environ à l’échelle nationale. Grâce à des prescriptions rationnelles, on estime que les économies annuelles pourraient atteindre 222 millions $ pour les programmes publics et 521 millions $ à l’échelle nationale. Conclusion La

  4. Bibliography on plutonium and its compounds; Bibliographie sur le plutonium et ses composes

    Energy Technology Data Exchange (ETDEWEB)

    Dirian, J; Choquet, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Collection of bibliographical references on plutonium and its principal compounds from 1942 to end of 1957. (author) [French] Compilation de references bibliographiques sur le plutonium et ses principaux composes de 1942 a fin 1957. (auteur)

  5. Noise analysis of grating-based x-ray differential phase-contrast imaging with angular signal radiography

    International Nuclear Information System (INIS)

    Faiz, Wali; Gao Kun; Wu Zhao; Wei Chen-Xi; Zan Gui-Bin; Tian Yang-Chao; Bao Yuan; Zhu Pei-Ping

    2017-01-01

    X-ray phase-contrast imaging is one of the novel techniques, and has potential to enhance image quality and provide the details of inner structures nondestructively. In this work, we investigate quantitatively signal-to-noise ratio (SNR) of grating-based x-ray phase contrast imaging (GBPCI) system by employing angular signal radiography (ASR). Moreover, photon statistics and mechanical error that is a major source of noise are investigated in detail. Results show the dependence of SNR on the system parameters and the effects on the extracted absorption, refraction and scattering images. Our conclusions can be used to optimize the system design for upcoming practical applications in the areas such as material science and biomedical imaging. (paper)

  6. Effets sur les patients des variations dans l’implantation d’un programme d’intervention sur le risque cardiométabolique à Montréal

    Directory of Open Access Journals (Sweden)

    Marie-Ève Beauregard

    2018-01-01

    Full Text Available Introduction : En 2011, l’Agence de la santé et des services sociaux de Montréal (ASSSM, en partenariat avec les Centres de santé et de services sociaux (CSSS de la région, a coordonné la mise en oeuvre d’un programme sur le risque cardiométabolique s’inspirant du Chronic Care Model. Ce programme destiné aux patients diabétiques ou hypertendus comporte une séquence de suivis individuels, des cours de groupe et des séances d’activité physique. Notre étude évalue l’impact de la variation dans l’implantation de certains aspects du programme entre les six CSSS participant à l’étude sur les résultats de santé des patients. Méthodologie : L’évaluation a été réalisée à l’aide d’un devis quasi-expérimental « avantaprès ». Des variables d’implantation ont été construites à partir de données colligées lors de l’analyse d’implantation concernant les ressources, la conformité au processus clinique prévu dans le programme régional, l’expérience du programme et la coordination interne au sein de l’équipe de soins. Des différences de différences utilisant des scores de propension ont été calculées pour les résultats d’HbA1c, l’atteinte de la cible de tension artérielle (TA et de deux cibles d’habitudes de vie (niveau d’activité physique et répartition des glucides alimentaires à 6 mois et à 12 mois de suivi, en fonction de l’exposition des patients à un degré plus ou moins important d’implantation de divers aspects du programme à l’étude. Résultats : Les résultats portent sur les 1 185 patients pour lesquels on disposait de données de suivi à 6 mois et les 992 patients pour le suivi à 12 mois. Les analyses de différences de différences ne révèlent aucune association claire entre le degré d’implantation des divers aspects du programme à l’étude et les résultats de santé chez les patients. Conclusion : Le programme produit des effets sur les

  7. Sécurité alimentaire : une lutte sur plusieurs fronts | CRDI - Centre ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    1 févr. 2011 ... En 1996, 180 pays – dont le Canada – ont participé à Rome au Sommet ... la Déclaration de Rome sur la sécurité alimentaire mondiale et le Plan .... de la finance, du marketing et de l'information à de petits exploitants afin ...

  8. Etude sur la prédiction de l'inversion de phase Phase Inversion Behavior for Liquid Dispersions

    Directory of Open Access Journals (Sweden)

    Decarre S.

    2006-12-01

    Full Text Available En écoulement diphasique eau-huile dans lequel une des phases est dispersée dans l'autre, il peut se produire sous certaine condition d'écoulement une inversion de phase, la phase continue devenant dispersée. Ce phénomène, qui contrôle la nature de la phase mouillant la paroi de la conduite dans laquelle s'écoulent les phases, a des conséquences importantes sur la corrosion et sur la perte de charge. Nous présentons un modèle d'inversion, basé sur une approche thermodynamique, valable pour tous les régimes d'écoulement. Les données expérimentales utilisées pour la validation du modèle sont issues d'une étude bibliographique. En écoulement laminaire, cette approche conduit à des résultats similaires à ceux du modèle de Yeh. Pour la plupart des données disponibles, ce modèle prédit bien la fraction critique pour laquelle l'inversion de phase se produit. In two phase oil-water dispersed flow, a phase inversion may occur whereby the continuous phase becomes dispersed. This phenomenon which controls the nature of the phase in contact with the pipe has a great importance on the corrosion and on the pressure drop. A model for the phase inversion is presented, it is based on a thermodynamic approach, and it is valid for all flow regimes. Experimental data from the litterature are used to validate the model. In laminar flow, this approach gives similar results to those obtained by Yeh. For most data, the model agrees well with the experimental data.

  9. L'incidence de la représentation politique des femmes sur la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    économie et débouchés économiques des femmes (CEDEF). Ce programme quinquennal est un partenariat réunissant le Department for International Development du Royaume-Uni, la William and Flora Hewlett Foundation et le CRDI. Axé sur les ...

  10. Discursos y prácticas de la cooperación Sur-Sur brasileña en materia agrícola en el África Subsahariana: el caso del ProSavana y del PAA África

    OpenAIRE

    de Andrade e Sousa, Maria Eduarda

    2016-01-01

    Este artículo aborda la Cooperación Sur-Sur (CSS) brasileña en el África Subsahariana, con el objetivo de investigar en qué medida las iniciativas en materia agrícola pueden contribuir a la seguridad alimentaria de la región. Para ello, dos proyectos, el ProSavana y el PAA África, han sido estudiados en detalle a fin de valorar sus potencialidades desde el punto de vista de la seguridad alimentaria y analizar hasta qué punto están en línea con los principios de la cooperación técnica brasileñ...

  11. Agriculture itinérante sur brûlis (AIB et plantes cultivées sur le haut Maroni: étude comparée chez les Aluku et les Wayana en Guyane française

    Directory of Open Access Journals (Sweden)

    Marie Fleury

    Full Text Available Résumé Vers la fin du 18e siècle, les Noirs marrons Aluku, descendants d’esclaves rebelles fuyant les plantations hollandaises et les Amérindiens Wayana, arrivant du Brésil, où ils fuyaient les chasseurs d’esclaves, se sont rencontrés sur le haut Maroni, en Guyane française. Ce partage d’un même lieu de vie a été l’occasion d’échanger un grand nombre de techniques, notamment en ce qui concerne l’agriculture itinérante sur brûlis, et les plantes cultivées. Toutefois notre étude montre que le culte des ancêtres chez les Noirs marrons a modifié leur cycle cultural (via la culture du riz, influençant ainsi leur gestion de l’environnement. De même la nature et la diversité des plantes cultivées diffèrent sensiblement en fonction des usages traditionnels et habitudes culinaires des deux sociétés. Les Aluku ont sélectionné de nombreuses espèces et variétés de plantes qui leur sont propres et sont liées à leurs racines africaines. Les Amérindiens cultivent des plantes spécifiques utiles au chamanisme (tabac et à leur artisanat traditionnel. De plus, leur perception de la nature implique des pratiques cultuelles différentes notamment avant le défrichage. Cette étude illustre l’influence de la diversité culturelle sur la gestion de l’agrobiodiversité et, de manière plus générale, sur l’adaptation de l’homme à son environnement.

  12. Variational contrast enhancement guided by global and local contrast measurements for single-image defogging

    Science.gov (United States)

    Zhou, Li; Bi, Du-Yan; He, Lin-Yuan

    2015-01-01

    The visibility of images captured in foggy conditions is impaired severely by a decrease in the contrasts of objects and veiling with a characteristic gray hue, which may limit the performance of visual applications out of doors. Contrast enhancement together with color restoration is a challenging mission for conventional fog-removal methods, as the degrading effect of fog is largely dependent on scene depth information. Nowadays, people change their minds by establishing a variational framework for contrast enhancement based on a physically based analytical model, unexpectedly resulting in color distortion, dark-patch distortion, or fuzzy features of local regions. Unlike previous work, our method treats an atmospheric veil as a scattering disturbance and formulates a foggy image as an energy functional minimization to estimate direct attenuation, originating from the work of image denoising. In addition to a global contrast measurement based on a total variation norm, an additional local measurement is designed in that optimal problem for the purpose of digging out more local details as well as suppressing dark-patch distortion. Moreover, we estimate the airlight precisely by maximization with a geometric constraint and a natural image prior in order to protect the faithfulness of the scene color. With the estimated direct attenuation and airlight, the fog-free image can be restored. Finally, our method is tested on several benchmark and realistic images evaluated by two assessment approaches. The experimental results imply that our proposed method works well compared with the state-of-the-art defogging methods.

  13. Des filets à nuages sur la crête d'El Tofo | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    adaptation aux changements climatiques que le CRDI subventionne. Entretien avec…propose des entrevues vidéos avec des chercheurs participant à des projets portant sur l'adaptation aux changements climati.

  14. Retour "écologique" sur la question des nitrates

    OpenAIRE

    Buson, Christian

    2012-01-01

    Un examen critique de la question des nitrates est proposé dans cet article, à la lumière des connaissances disponibles dans différentes disciplines. Au plan sanitaire, la norme sur l’eau potable établie depuis plusieurs décennies résulte d’une erreur ancienne aujourd’hui reconnue comme telle. Les nitrates n’engendrent aucun trouble sanitaire et les griefs tels que la méthémoglobinémie du nourrisson, ou le risque de cancer du à la formation de nitrosamines, qui les ont...

  15. Zoom on India | Gros plan sur l’Inde

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Indian Energy Production and Consumption (in Million Tonnes of Oil EquivalentProduction et consommation d’énergie en Inde (en millions de tonnes d’équivalent pétroleSource: World Bank, World Bank Development Indicators, 2010.Indian Oil, Gas and Coal Imports (in Million Tonnes of Oil Equivalent, 2008*Importations indiennes de pétrole, de gaz et de charbon (en millions de tonnes d’équivalent pétrole, 2008** 2009 for coal data | 2009 pour les données sur le charbon.Sources: British Petroleum...

  16. Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms.

    Science.gov (United States)

    Rogosnitzky, Moshe; Branch, Stacy

    2016-06-01

    Gadolinium chelates are widely used as contrast media for magnetic resonance imaging. The approved gadolinium-based contrast agents (GBCAs) have historically been considered safe and well tolerated when used at recommended dosing levels. However, for nearly a decade, an association between GBCA administration and the development of nephrogenic systemic fibrosis (NSF) has been recognized in patients with severe renal impairment. This has led to modifications in clinical practices aimed at reducing the potential and incidence of NSF development. Newer reports have emerged regarding the accumulation of gadolinium in various tissues of patients who do not have renal impairment, including bone, brain, and kidneys. Despite the observations of gadolinium accumulation in tissues regardless of renal function, very limited clinical data regarding the potential for and mechanisms of toxicity is available. This significant gap in knowledge warrants retrospective cohort study efforts, as well as prospective studies that involve gadolinium ion (Gd(3+)) testing in patients exposed to GBCA. This review examines the potential biochemical and molecular basis of gadolinium toxicity, possible clinical significance of gadolinium tissue retention and accumulation, and methods that can limit gadolinium body burden.

  17. Regroupement des statistiques sur le secteur des TIC et analyse ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    La présence et l'influence des technologies de l'information et de la communication (TIC) continuent de s'élargir et de s'accroître, tout comme leurs répercussions sur le développement économique. Toutefois, il reste encore beaucoup de travail à faire avant de pouvoir comprendre d'une manière systématique et ...

  18. Influence des technologies d'information et de la communication sur ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Influence des technologies d'information et de la communication sur les mutations du marché du travail au Sénégal. Les technologies d'information et de la communication (TIC) sont devenues un élément-clé des stratégies de développement économique et réduction de la pauvreté au Sénégal. Cependant, quoique la ...

  19. Journal Afrika Statistika ISSN 0852-0305 Sur les estimateurs du ...

    African Journals Online (AJOL)

    Sur les estimateurs du maximum de vraisemblance dans les mod`eles multiplicatifs de Poisson et binomiale négative. 298. [1], Berk [2], Bickel et Doksum [3], ..... montrons l'implication (A2) ⇒(A1). Soit ˆµ l'EMV du mod`ele, alors toutes ses composantes sont strictement positives, et, d'apr`es le lemme 3, il vérifie l'équation.

  20. Ciudades de madera. Patrimonio del sur, un bien reciclable

    Directory of Open Access Journals (Sweden)

    Edward Rojas V.

    1994-05-01

    Full Text Available Hace algunos años reflexionaba en una de las páginas del número especial (N° 12 de la Revista Arquitecturas del Sur, dedicado a la ciudad de Castro, que la arquitectura así como la fotografía en la medida en que son registros concretos de la acción humana tienen la cualidad de atrapar con su materialidad ese preciso instante de la historia de la que son productos.

  1. Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the KATP channel subunits SUR2A and Kir6.2

    Science.gov (United States)

    Dupuis, Julien P; Revilloud, Jean; Moreau, Christophe J; Vivaudou, Michel

    2008-01-01

    Cardiac ATP-sensitive potassium (KATP) channels are metabolic sensors formed by the association of the inward rectifier potassium channel Kir6.2 and the sulphonylurea receptor SUR2A. SUR2A adjusts channel gating as a function of intracellular ATP and ADP and is the target of pharmaceutical openers and blockers which, respectively, up- and down-regulate Kir6.2. In an effort to understand how effector binding to SUR2A translates into Kir6.2 gating modulation, we examined the role of a 65-residue SUR2A fragment linking transmembrane domain TMD2 and nucleotide-binding domain NBD2 that has been shown to interact with Kir6.2. This fragment of SUR2A was replaced by the equivalent residues of its close homologue, the multidrug resistance protein MRP1. The chimeric construct was expressed in Xenopus oocytes and characterized using the patch-clamp technique. We found that activation by MgADP and synthetic openers was greatly attenuated although apparent affinities were unchanged. Further chimeragenetic and mutagenetic studies showed that mutation of three residues, E1305, I1310 and L1313 (rat numbering), was sufficient to confer this defective phenotype. The same mutations had no effects on channel block by the sulphonylurea glibenclamide or by ATP, suggesting a role for these residues in activatory – but not inhibitory – transduction processes. These results indicate that, within the KATP channel complex, the proximal C-terminal of SUR2A is a critical link between ligand binding to SUR2A and Kir6.2 up-regulation. PMID:18450778

  2. SU-E-J-16: Automatic Image Contrast Enhancement Based On Automatic Parameter Optimization for Radiation Therapy Setup Verification

    International Nuclear Information System (INIS)

    Qiu, J; Li, H. Harlod; Zhang, T; Yang, D; Ma, F

    2015-01-01

    Purpose: In RT patient setup 2D images, tissues often cannot be seen well due to the lack of image contrast. Contrast enhancement features provided by image reviewing software, e.g. Mosaiq and ARIA, require manual selection of the image processing filters and parameters thus inefficient and cannot be automated. In this work, we developed a novel method to automatically enhance the 2D RT image contrast to allow automatic verification of patient daily setups as a prerequisite step of automatic patient safety assurance. Methods: The new method is based on contrast limited adaptive histogram equalization (CLAHE) and high-pass filtering algorithms. The most important innovation is to automatically select the optimal parameters by optimizing the image contrast. The image processing procedure includes the following steps: 1) background and noise removal, 2) hi-pass filtering by subtracting the Gaussian smoothed Result, and 3) histogram equalization using CLAHE algorithm. Three parameters were determined through an iterative optimization which was based on the interior-point constrained optimization algorithm: the Gaussian smoothing weighting factor, the CLAHE algorithm block size and clip limiting parameters. The goal of the optimization is to maximize the entropy of the processed Result. Results: A total 42 RT images were processed. The results were visually evaluated by RT physicians and physicists. About 48% of the images processed by the new method were ranked as excellent. In comparison, only 29% and 18% of the images processed by the basic CLAHE algorithm and by the basic window level adjustment process, were ranked as excellent. Conclusion: This new image contrast enhancement method is robust and automatic, and is able to significantly outperform the basic CLAHE algorithm and the manual window-level adjustment process that are currently used in clinical 2D image review software tools

  3. SU-E-J-16: Automatic Image Contrast Enhancement Based On Automatic Parameter Optimization for Radiation Therapy Setup Verification

    Energy Technology Data Exchange (ETDEWEB)

    Qiu, J [Taishan Medical University, Taian, Shandong (China); Washington University in St Louis, St Louis, MO (United States); Li, H. Harlod; Zhang, T; Yang, D [Washington University in St Louis, St Louis, MO (United States); Ma, F [Taishan Medical University, Taian, Shandong (China)

    2015-06-15

    Purpose: In RT patient setup 2D images, tissues often cannot be seen well due to the lack of image contrast. Contrast enhancement features provided by image reviewing software, e.g. Mosaiq and ARIA, require manual selection of the image processing filters and parameters thus inefficient and cannot be automated. In this work, we developed a novel method to automatically enhance the 2D RT image contrast to allow automatic verification of patient daily setups as a prerequisite step of automatic patient safety assurance. Methods: The new method is based on contrast limited adaptive histogram equalization (CLAHE) and high-pass filtering algorithms. The most important innovation is to automatically select the optimal parameters by optimizing the image contrast. The image processing procedure includes the following steps: 1) background and noise removal, 2) hi-pass filtering by subtracting the Gaussian smoothed Result, and 3) histogram equalization using CLAHE algorithm. Three parameters were determined through an iterative optimization which was based on the interior-point constrained optimization algorithm: the Gaussian smoothing weighting factor, the CLAHE algorithm block size and clip limiting parameters. The goal of the optimization is to maximize the entropy of the processed Result. Results: A total 42 RT images were processed. The results were visually evaluated by RT physicians and physicists. About 48% of the images processed by the new method were ranked as excellent. In comparison, only 29% and 18% of the images processed by the basic CLAHE algorithm and by the basic window level adjustment process, were ranked as excellent. Conclusion: This new image contrast enhancement method is robust and automatic, and is able to significantly outperform the basic CLAHE algorithm and the manual window-level adjustment process that are currently used in clinical 2D image review software tools.

  4. Technical Training: Cycle d'Information/Formation sur l'Environnement d'Automatisme SCHNEIDER

    CERN Multimedia

    Raymond Brun

    2005-01-01

    Après la présention technique du 2 mars 2005 sur UNITY-Pro, deux autres présentations sur les nouveautés Schneider 2004/2005, dédiées aux utilisateurs CERN, auront lieu dans les locaux de l'enseignement technique (bât. 593, salle 13) aux dates suivantes : Mercredi 13 avril de 9h à 12h : Gamme Dialogue Homme-Machine (HMI) => Présentation et démonstration. Nouveaux terminaux tactiles Gamme XBT-G Logiciel de configuration visio-Designer Factory-Cast-HMI Distributed HMI Smart IPC (PC-Indusriel avec écran tactile rackable) Mercredi 11 Mai de 9h à 12h : Gamme Entrées/Sorties => Présentation et démonstration ADVANTIS (STB, OTB, ...) TWIDO (Nouvel UC et Connexion Ethernet) Nota : Ces formations, essentiellement techniques et pratiques, sont destinées aux personnes du CERN qui : ·  veulent connaître les nouvelles possibilités o...

  5. Quantitative structure-property relationship (correlation analysis) of phosphonic acid-based chelates in design of MRI contrast agent.

    Science.gov (United States)

    Tiwari, Anjani K; Ojha, Himanshu; Kaul, Ankur; Dutta, Anupama; Srivastava, Pooja; Shukla, Gauri; Srivastava, Rakesh; Mishra, Anil K

    2009-07-01

    Nuclear magnetic resonance imaging is a very useful tool in modern medical diagnostics, especially when gadolinium (III)-based contrast agents are administered to the patient with the aim of increasing the image contrast between normal and diseased tissues. With the use of soft modelling techniques such as quantitative structure-activity relationship/quantitative structure-property relationship after a suitable description of their molecular structure, we have studied a series of phosphonic acid for designing new MRI contrast agent. Quantitative structure-property relationship studies with multiple linear regression analysis were applied to find correlation between different calculated molecular descriptors of the phosphonic acid-based chelating agent and their stability constants. The final quantitative structure-property relationship mathematical models were found as--quantitative structure-property relationship Model for phosphonic acid series (Model 1)--log K(ML) = {5.00243(+/-0.7102)}- MR {0.0263(+/-0.540)}n = 12 l r l = 0.942 s = 0.183 F = 99.165 quantitative structure-property relationship Model for phosphonic acid series (Model 2)--log K(ML) = {5.06280(+/-0.3418)}- MR {0.0252(+/- .198)}n = 12 l r l = 0.956 s = 0.186 F = 99.256.

  6. Essai d’une méthodologie d’analyse des données d’Internet sur un ordinateur

    OpenAIRE

    Géraldine Foin

    2017-01-01

    Dans l’étude de l’environnement numérique dans lequel les individus vivent et évoluent, des problèmes méthodologiques peuvent se poser pour les chercheurs en sciences humaines et sociales. Cet article s’interroge sur la compatibilité des outils classiques en sciences sociales pour l’étude des pratiques numériques sur un écran, celui de l’ordinateur. En effet, l’usage classique d’entretiens, de questionnaires ou d’observations ne suffit plus pour recueillir avec précision les données relatives...

  7. Commentaires à propos de la loi française sur le harcèlement moral au travail

    OpenAIRE

    Marie-France Hirigoyen; Claire Bonafons

    2005-01-01

    Les auteurs montreront comment en France, à partir d’une simple description de la souffrance engendrée par le harcèlement, on a aboutit rapidement à une loi sanctionnant ce fléau, puis ils feront le point sur les jurisprudences et sur l’évolution des comportements entraînés par cette loi et enfin, ils proposeront des axes de recherches et des pistes d’amélioration des dispositions législatives existantes.The authors will show how in France, starting with a simple description of the suffering ...

  8. Commentaires à propos de la loi française sur le harcèlement moral au travail

    OpenAIRE

    Hirigoyen, Marie-France; Bonafons, Claire

    2013-01-01

    Les auteurs montreront comment en France, à partir d’une simple description de la souffrance engendrée par le harcèlement, on a aboutit rapidement à une loi sanctionnant ce fléau, puis ils feront le point sur les jurisprudences et sur l’évolution des comportements entraînés par cette loi et enfin, ils proposeront des axes de recherches et des pistes d’amélioration des dispositions législatives existantes. The authors will show how in France, starting with a simple description of the suffer...

  9. Incidences des programmes d'acquisition de compétences sur les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cette recherche jouit de l'appui du programme Croissance de l'économie et débouchés économiques des femmes (programme CEDEF). Ce programme quinquennal est un partenariat réunissant le Department for International Development du Royaume-Uni, la William and Flora Hewlett Foundation et le CRDI. Axé sur les ...

  10. Wide-Field Vibrational Phase Contrast Imaging Based on Coherent Anti-Stokes Raman Scattering Holography

    International Nuclear Information System (INIS)

    Lv Yong-Gang; Ji Zi-Heng; Dong Da-Shan; Gong Qi-Huang; Shi Ke-Bin

    2015-01-01

    We propose and implement a wide-field vibrational phase contrast detection to obtain imaging of imaginary components of third-order nonlinear susceptibility in a coherent anti-Stokes Raman scattering (CARS) microscope with full suppression of the non-resonant background. This technique is based on the unique ability of recovering the phase of the generated CARS signal based on holographic recording. By capturing the phase distributions of the generated CARS field from the sample and from the environment under resonant illumination, we demonstrate the retrieval of imaginary components in the CARS microscope and achieve background free coherent Raman imaging. (paper)

  11. Comparison and Contrast in Perceptual Categorization

    Science.gov (United States)

    Hampton, James A.; Estes, Zachary; Simmons, Claire L.

    2005-01-01

    People categorized pairs of perceptual stimuli that varied in both category membership and pairwise similarity. Experiments 1 and 2 showed categorization of 1 color of a pair to be reliably contrasted from that of the other. This similarity-based contrast effect occurred only when the context stimulus was relevant for the categorization of the…

  12. State of the Art of X-ray Speckle-Based Phase-Contrast and Dark-Field Imaging

    Directory of Open Access Journals (Sweden)

    Marie-Christine Zdora

    2018-04-01

    Full Text Available In the past few years, X-ray phase-contrast and dark-field imaging have evolved to be invaluable tools for non-destructive sample visualisation, delivering information inaccessible by conventional absorption imaging. X-ray phase-sensing techniques are furthermore increasingly used for at-wavelength metrology and optics characterisation. One of the latest additions to the group of differential phase-contrast methods is the X-ray speckle-based technique. It has drawn significant attention due to its simple and flexible experimental arrangement, cost-effectiveness and multimodal character, amongst others. Since its first demonstration at highly brilliant synchrotron sources, the method has seen rapid development, including the translation to polychromatic laboratory sources and extension to higher-energy X-rays. Recently, different advanced acquisition schemes have been proposed to tackle some of the main limitations of previous implementations. Current applications of the speckle-based method range from optics characterisation and wavefront measurement to biomedical imaging and materials science. This review provides an overview of the state of the art of the X-ray speckle-based technique. Its basic principles and different experimental implementations as well as the the latest advances and applications are illustrated. In the end, an outlook for anticipated future developments of this promising technique is given.

  13. Lignes directrices canadiennes sur la rhinosinusite chronique

    Science.gov (United States)

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  14. Une économie axée sur l'épanouissement des jeunes | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    7 août 2013 ... Le projet porte sur des questions transversales telles que les obstacles à la ... par la National Academy of Science and Technology des Philippines. .... Mme Rustagi est professeure et codirectrice de l'Institute for Human ...

  15. A smart magnetic resonance imaging contrast agent responsive to adenosine based on a DNA aptamer-conjugated gadolinium complex.

    Science.gov (United States)

    Xu, Weichen; Lu, Yi

    2011-05-07

    We report a general strategy for developing a smart MRI contrast agent for the sensing of small molecules such as adenosine based on a DNA aptamer that is conjugated to a Gd compound and a protein streptavidin. The binding of adenosine to its aptamer results in the dissociation of the Gd compound from the large protein, leading to decreases in the rotational correlation time and thus change of MRI contrast. © The Royal Society of Chemistry 2011

  16. Decontamination tests on cotton materials; Essais de decontamination sur tissus de coton

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, P; Pelletier, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    It is shown that versene gives the best decontamination results on cotton materials soiled by a mixture of fission products. (author) [French] On a montre que le versene donne les meilleurs resultats de decontamination sur des tissus de coton souilles par un melange de produits de fission. (auteur)

  17. Bourse de recherche postdoctorale sur l'Amérique centrale et les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Nouveau webinaire IWRA/CRDI sur les changements climatiques et la gestion adaptive de l'eau. L'Association internationale de ressources en eau (IWRA), en étroite collaboration avec le CRDI, organise un webinaire intitulé "Changements climatiques et gestion adaptive de l'eau: des... Voir davantageNouveau webinaire ...

  18. Effet de la rugosité de surface sur les performances du contact ...

    African Journals Online (AJOL)

    Effet de la rugosité de surface sur les performances du contact segment- chemise dans un moteur à combustion interne. The effect of surface roughness on the performances of liner-piston ring contact in internal combustion engine. Amar Ayad. *. , Amar Skendraoui & Ammar Haiahem. Laboratoire de Mécanique Industrielle ...

  19. Contrast based band selection for optimized weathered oil detection in hyperspectral images

    Science.gov (United States)

    Levaux, Florian; Bostater, Charles R., Jr.; Neyt, Xavier

    2012-09-01

    Hyperspectral imagery offers unique benefits for detection of land and water features due to the information contained in reflectance signatures such as the bi-directional reflectance distribution function or BRDF. The reflectance signature directly shows the relative absorption and backscattering features of targets. These features can be very useful in shoreline monitoring or surveillance applications, for example to detect weathered oil. In real-time detection applications, processing of hyperspectral data can be an important tool and Optimal band selection is thus important in real time applications in order to select the essential bands using the absorption and backscatter information. In the present paper, band selection is based upon the optimization of target detection using contrast algorithms. The common definition of the contrast (using only one band out of all possible combinations available within a hyperspectral image) is generalized in order to consider all the possible combinations of wavelength dependent contrasts using hyperspectral images. The inflection (defined here as an approximation of the second derivative) is also used in order to enhance the variations in the reflectance spectra as well as in the contrast spectrua in order to assist in optimal band selection. The results of the selection in term of target detection (false alarms and missed detection) are also compared with a previous method to perform feature detection, namely the matched filter. In this paper, imagery is acquired using a pushbroom hyperspectral sensor mounted at the bow of a small vessel. The sensor is mechanically rotated using an optical rotation stage. This opto-mechanical scanning system produces hyperspectral images with pixel sizes on the order of mm to cm scales, depending upon the distance between the sensor and the shoreline being monitored. The motion of the platform during the acquisition induces distortions in the collected HSI imagery. It is therefore

  20. Características, referentes y líneas maestras de la crítica literaria realizada en Cuadernos del Sur

    Directory of Open Access Journals (Sweden)

    Rodríguez Jiménez, Antonio

    2015-12-01

    Full Text Available This article approaches the features, references points and lines of literary criticism expressed in the literary supplement Cuadernos del Sur. The work constant in the literary field provided a critical authority and subsequently independence in the quality of the works studied. It shows how the gamble of criticism was continuous and strong to the dissemination of culture. It covers discussions and debates about literary criticism between 1986 and 2008. It explains how Cuadernos del Sur has been a guide to enlighten readers by the tangled jungle of the manifestations of thought, especially in the world of books, with a critical view of aesthetic approaches freely when prosecuting the literary work. It analyzes how Cuadernos del Sur it marks a path of dialogue and turns into platform of expression of critics and authors.Este artículo aborda las características, los referentes y las líneas maestras de la crítica literaria desarrollada en el suplemento literario Cuadernos del Sur. La constancia en el terreno crítico aportó una autoridad que posteriormente generó independencia en la calidad de las obras estudiadas. Se muestra cómo la apuesta crítica fue constante y de firme compromiso con la difusión de la cultura. Se abordan discusiones y debates en torno a la crítica desarrollada entre 1986 y 2008. Se explica cómo Cuadernos del Sur ha sido una guía para iluminar a los lectores por la intrincada selva de las manifestaciones del pensamiento, sobre todo por el mundo de los libros, que ha realizado una visión crítica con libertad de planteamientos estéticos a la hora de enjuiciar la obra literaria. Se analiza cómo Cuadernos del Sur marca un camino de diálogo y se convierte en tribuna abierta de expresión de críticos y autores.

  1. La liebre europea, Lepus europaeus (Mammalia, Leporidae, especie invasora en el sur del Perú

    Directory of Open Access Journals (Sweden)

    Daniel Cossíos

    2013-06-01

    Full Text Available La liebre europea fue introducida entre finales del siglo XIX y comienzos del siglo XX a Argentina y Chile, y desde entonces ha avanzado a través de América del Sur. En 1983 la liebre había alcanzado el sur de Brasil, el departamento de Tarija en el sur de Bolivia y el río Copiapó en Chile, encontrándose ausente en el Perú. En los años 2002 y 2004 se observó varios ejemplares de liebre en estado silvestre en los departamentos peruanos de Tacna y Arequipa, hasta una altitud de 4300 m. Según entrevistas hechas a pobladores de esas zonas, la liebre habría llegado al Perú entre los años 1995 y 1998, lo que significa una velocidad de dispersión mínima de 44,34 km/año partiendo de Tarija. Los entrevistados dijeron no dar uso a la liebre y que ésta les trae problemas al consumir la vegetación. La presente nota es una alerta sobre la llegada de la liebre europea al Perú y los posibles efectos de su presencia.

  2. Suivi sur le programme de mentorat de journalistes scientifiques des ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    12 oct. 2010 ... Il doit rédiger un article sur l'éducation et les droits de l'homme. Mais les chercheurs refusent de communiquer leurs informations, le journaliste doit présenter une requête par écrit. Ce qu'il fait. Godefroy Chabi n'obtiendra jamais de réponse. Une entrave intolérable aux libertés d'accès à l'information ?

  3. Incidence de la densite sur les performances de production, la ...

    African Journals Online (AJOL)

    L'étude montre l'incidence du facteur densités sur les résultats d'élevage, le rendement carcasse, la qualité organoleptique et le comportement de deux souches de poulets chair élevées au Bénin. Au total, 180 poulets de chair soit 90 poulets de chacune des souches Ross et Cobb 500 répartis en 4 traitements de trois ...

  4. Nouvelles de l'Italie sur la linguistique et l'education

    Directory of Open Access Journals (Sweden)

    Raffaele Simone

    1984-12-01

    Full Text Available L'auteur donne. des informations sur l'état actuel des débats concernant le développement du langage dans l'école italienne d'aujourd'hui, et prop6se U:ne "nouvelle" notion de linguistique appliquée, considérée en tant que confrontation de systèmes de sens, plutôt de systèmes de formes.

  5. Effet de la salinité sur quelques traits physiologiques et ...

    African Journals Online (AJOL)

    Administrateur

    ﺔﯾزوﻣﺳﻻا تﺎﯾﻣﺣﻣ. -. Atriplex halimus L. Résumé. Le présent travail traite de l'effet de la salinité sur quelques réponses physiologiques et biochimiques d'une espèce, Atriplex halimus L. Des plantules sont soumises à des analyses de la biomasse, du statut énergétique. (teneurs en pigments chlorophylliens), du dosage ...

  6. A local contrast based approach to threshold segmentation for PET target volume delineation

    International Nuclear Information System (INIS)

    Drever, Laura; Robinson, Don M.; McEwan, Alexander; Roa, Wilson

    2006-01-01

    Current radiation therapy techniques, such as intensity modulated radiation therapy and three-dimensional conformal radiotherapy rely on the precise delivery of high doses of radiation to well-defined volumes. CT, the imaging modality that is most commonly used to determine treatment volumes cannot, however, easily distinguish between cancerous and normal tissue. The ability of positron emission tomography (PET) to more readily differentiate between malignant and healthy tissues has generated great interest in using PET images to delineate target volumes for radiation treatment planning. At present the accurate geometric delineation of tumor volumes is a subject open to considerable interpretation. The possibility of using a local contrast based approach to threshold segmentation to accurately delineate PET target cross sections is investigated using well-defined cylindrical and spherical volumes. Contrast levels which yield correct volumetric quantification are found to be a function of the activity concentration ratio between target and background, target size, and slice location. Possibilities for clinical implementation are explored along with the limits posed by this form of segmentation

  7. Measuring streetscape complexity based on the statistics of local contrast and spatial frequency.

    Directory of Open Access Journals (Sweden)

    André Cavalcante

    Full Text Available Streetscapes are basic urban elements which play a major role in the livability of a city. The visual complexity of streetscapes is known to influence how people behave in such built spaces. However, how and which characteristics of a visual scene influence our perception of complexity have yet to be fully understood. This study proposes a method to evaluate the complexity perceived in streetscapes based on the statistics of local contrast and spatial frequency. Here, 74 streetscape images from four cities, including daytime and nighttime scenes, were ranked for complexity by 40 participants. Image processing was then used to locally segment contrast and spatial frequency in the streetscapes. The statistics of these characteristics were extracted and later combined to form a single objective measure. The direct use of statistics revealed structural or morphological patterns in streetscapes related to the perception of complexity. Furthermore, in comparison to conventional measures of visual complexity, the proposed objective measure exhibits a higher correlation with the opinion of the participants. Also, the performance of this method is more robust regarding different time scenarios.

  8. La réputation de l'audit externe et les mécanismes de gouvernement d'entreprise: Interactions et effet sur la performance

    OpenAIRE

    Fodil Adjaoud; Chokri Mamoghli; Fatma Siala

    2007-01-01

    International audience; L'objectif de cette étude est d'analyser l'impact de la combinaison de la réputation de l'audit externe et des mécanismes internes de gouvernement d'entreprise sur la performance. Les tests menés sur un échantillon de 289 entreprises canadiennes sur trois ans supportent l'hypothèse de substitution proposée par la littérature. Nos résultats montrent qu'une meilleure réputation de l'audit pourrait ne plus constituer une prérogative aussi bien pour les actionnaires que po...

  9. Histoire d'une cité scientifique le campus du CNRS à Gif-sur-Yvette (1946-2016)

    CERN Document Server

    2016-01-01

    L'histoire du campus de Gif-sur-Yvette, cité scientifique de renommée internationale, commence en 1946, à l'heure de la reconstruction de la recherche française, ajuste après le deuxième conflit mondial. L'histoire du campus de Gif-sur-Yvette, cité scientifique de renommée internationale, commence en 1946, à l'heure de la reconstruction de la recherche française, ajuste après le deuxième conflit mondial. À cette époque, l'on cherche à favoriser l'émergence d'études nouvelles, à soutenir les travaux fondamentaux sans s'interdire de réfléchir à leurs applications, ou encore à stimuler l'interdisciplinarité. L'acquisition du domaine par le CNRS reflète alors l'ambition de son directeur, Frédéric Joliot-Curie, de refonder la Recherche scientifique et de restaurer son rayonnement. Depuis, le campus de Gif-sur-Yvette a connu une formidable aventure, aussi bien humaine que scientifique. Pionnier dans de nombreux domaines, en biologie, en chimie mais aussi en sciences du climat et de l'env...

  10. Equilibrium-phase MR angiography: Comparison of unspecific extracellular and protein-binding gadolinium-based contrast media with respect to image quality.

    Science.gov (United States)

    Erb-Eigner, Katharina; Taupitz, Matthias; Asbach, Patrick

    2016-01-01

    The purpose of this study was to compare contrast and image quality of whole-body equilibrium-phase high-spatial-resolution MR angiography using a non-protein-binding unspecific extracellular gadolinium-based contrast medium with that of two contrast media with different protein-binding properties. 45 patients were examined using either 15 mL of gadobutrol (non-protein-binding, n = 15), 32 mL of gadobenate dimeglumine (weakly protein binding, n = 15) or 11 mL gadofosveset trisodium (protein binding, n = 15) followed by equilibrium-phase high-spatial-resolution MR-angiography of four consecutive anatomic regions. The time elapsed between the contrast injection and the beginning of the equilibrium-phase image acquisition in the respective region was measured and was up to 21 min. Signal intensity was measured in two vessels per region and in muscle tissue. Relative contrast (RC) values were calculated. Vessel contrast, artifacts and image quality were rated by two radiologists in consensus on a five-point scale. Compared with gadobutrol, gadofosveset trisodium revealed significantly higher RC values only when acquired later than 15 min after bolus injection. Otherwise, no significant differences between the three contrast media were found regarding vascular contrast and image quality. Equilibrium-phase high-spatial-resolution MR-angiography using a weakly protein-binding or even non-protein-binding contrast medium is equivalent to using a stronger protein-binding contrast medium when image acquisition is within the first 15 min after contrast injection, and allows depiction of the vasculature with high contrast and image quality. The protein-binding contrast medium was superior for imaging only later than 15 min after contrast medium injection. Copyright © 2015 John Wiley & Sons, Ltd.

  11. Lambeau Expanse du Cuir Chevelu dans la Couverture des Alopecies Cicatricielles sur Sequelles de Brulures. A Propos d'une Observation

    Science.gov (United States)

    El Mazouz, S.; Hafidi, J.; Fejjal, N.; Mejjati, H.; Cherkab, L.; Gharib, N.; Abbassi, A.

    2010-01-01

    Summary Les séquelles esthétiques des alopécies cicatricielles sur séquelles de brûlures sont responsables de préjudices empêchant parfois la réinsertion sociale du patient, surtout chez les sujets de sexe féminin. Le cuir chevelu permet la réalisation de lambeaux permettant de couvrir ces alopécies. Les Auteurs décrivent le cas d'une jeune patiente victime d'une alopécie cicatricielle sur séquelles de brûlures chez qui ils ont réalisé un lambeau expansé du cuir chevelu et mettent le point sur la prise en charge de ces lésions à travers ce cas clinique et une revue de littérature. PMID:21991195

  12. Variabilidad de la abundancia de zooplancton en Bahía Magdalena Baja California Sur, México (1997-2001 Zooplankton abundance variability in Magdalena Bay, Baja California Sur, Mexico (1997-2001

    Directory of Open Access Journals (Sweden)

    Sergio Hernández-Trujillo

    2010-01-01

    Full Text Available Se analizaron muestras de zooplancton de 16 campañas oceanógraficas, efectuadas en Bahía Magdalena, Baja California Sur, México, entre agosto de 1997 y marzo de 2001. Se identificó un total de 26 grupos taxonómicos, de los cuales los más abundantes y frecuentes fueron copépodos y quetognatos; en 2000-2001 se observó una tendencia a disminuir entre 10 y 20 el número de grupos de zooplancton. La biomasa zooplanctónica y abundancia de copépodos disminuyeron en el periodo de estudio, en contraste con los quetognatos que tuvieron un ligero aumento. Las fluctuaciones de abundancia de zooplancton no estuvieron relacionadas con la concentración de clorofila-α, a diferencia de los máximos de abundancia de zooplancton, que estuvieron asociados a los cambios de la temperatura superficial del mar. El ciclo estacional de la abundancia del zooplancton en Bahía Magdalena, indicó que en invierno el promedió fue mayor de 65.000 ind 100 m-3 , valor que aumentó en primavera a más de 99.000 ind 100 m-3 , se mantuvo en verano alrededor de 100.000 ind 100 m-3 y en otoño descendió rápidamente a casi 40.000 ind 100 m-3.Zooplankton were studied from 16 oceanographic surveys carried out in Magdalena Bay, Baja California Sur, Mexico, between August 1997 and March 2001. Twenty-six taxonomic groups were identified, the most abundant and frequent of which were copepods and chaetognaths. In 2000-2001, the number of zooplankton groups tended to decrease by 10 to 20. Both zooplankton biomass and copepod abundance declined, unlike chaetognaths, which increased slightly. Fluctuations in zooplankton abundance were independent of the chlorophyll-a concentration, whereas the maximum zooplankton abundances were associated with changes in the sea surface temperature. The seasonal zooplankton abundance cycle in Magdalena Bay indicated that, in winter, the averaged was than 65,000 ind 100 m-3 , a value that increased to more than 99,000 ind 100 m-3 in spring

  13. Renforcement de la justice sexospécifique au Nigeria : regard sur la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Renforcement de la justice sexospécifique au Nigeria : regard sur la participation citoyenne des femmes. Au Nigeria, un large éventail de facteurs historiques, politiques et culturels tantôt entravent, tantôt favorisent une participation citoyenne des femmes respectueuse de leurs droits. Cette subvention permettra aux ...

  14. Savoir traditionnel sur les plantes antipaludiques à propriétés ...

    African Journals Online (AJOL)

    Savoir traditionnel sur les plantes antipaludiques à propriétés analgésiques, utilisées dans le district de Bamako (Mali). A Dénou, K Koudouvo, A Togola, M Haïdara, S.M Dembélé, F.N. Ballo, R Sanogo, D Diallo, M Gbeassor ...

  15. Jean-Baptiste Comby (dir.), Enquêter sur l’internationalisation des biens médiatiques et culturels

    OpenAIRE

    Mouchard, Laure

    2018-01-01

    Issu de réflexions menées lors d’un séminaire du Centre d’analyse et de recherche interdisciplinaire sur les médias consacré à l’internationalisation des médias, l’ouvrage dirigé et introduit par Jean-Baptiste Comby prend le parti de « sociologiser » l’étude des phénomènes d’internationalisation des biens médiatiques et culturels, thème que l’auteur estime davantage investi par les historiens, les économistes, les politistes et les sémiologues. En faisant retour sur l’histoire des études de l...

  16. Devenir victime des pesticides:Le recours au droit et ses effets sur la mobilisation des agriculteurs Phyto-victimes

    OpenAIRE

    Jouzel, Jean-Noël; Prete, Giovanni

    2014-01-01

    Cet article analyse les effets du recours au droit sur la mobilisation des travailleurs agricoles victimes des pesticides. Il repose sur une enquête qualitative auprès des membres de l’association Phyto-victimes, qui réunit ces agriculteurs, ainsi que de leurs proches et des professionnels du droit avec lesquels ils interagissent. À partir de ce matériau, nous retraçons les parcours suivis par les agriculteurs pour obtenir une reconnaissance de leur statut de victimes des pesticides. Nous ren...

  17. Proyecto educativo y pastoral para los niños trabajadores en el mercado mayorista del sur de Quito

    OpenAIRE

    Ibarra Sandoval, Fredy

    2005-01-01

    El presente trabajo investigativo: “Proyecto Educativo y Pastoral para los niños trabajadores en el Mercado Mayorista del sur de Quito”, fue seleccionado con el objetivo de presentar una parte de la realidad actual educativa y pastoral por la que atraviesan los niños que trabajaban en el Mercado Mayorista, ubicado al Sur de Quito. La Educación es un derecho y un deber de todo ciudadano, por tanto creo imprescindible hacer respetar y apoyar para que esta gestión sea diligente...

  18. Les dégâts de la grêle sur les cultures: l'averse du 1er juin 1993 dans le Saumurois

    Directory of Open Access Journals (Sweden)

    Freddy VINET

    1994-12-01

    Full Text Available La cartographie fine des dégâts de la grêle sur le vignoble du Saumurois permet d’obtenir des informations intéressantes sur le déroulement des averses de grêle: phase de concentration, coeur de grêle, dissipation.

  19. Soudage par explosion thermique sous charge de cermets poreux à base de TiC-Ni sur substrat en acier-comportement tribologique Welding of porous TiC–Ni based cermets on substrate steel by thermal explosion under load-tribological behaviour

    Directory of Open Access Journals (Sweden)

    Lemboub Samia

    2013-11-01

    Full Text Available Dans ce travail, nous nous intéressons à l'élaboration de cermets à base de TiC-Ni par dispersion de particules de carbures, oxydes ou borures dans une matrice de nickel, grâce à la technique de l'explosion thermique sous une charge de 20 MPa. La combustion de mélanges actifs (Ti-C-Ni-An où An = Al2O3, MgO, SiC, TiB2, WC, basée sur la réaction de synthèse de TiC (ΔHf298K = −184 kJ/mole, génère des cermets complexes. Un court maintien sous charge du cermet à 1373 K, après l'explosion thermique, permet son soudage sur un substrat en acier XC55. Les cermets obtenus dans ces conditions demeurent poreux et conservent une porosité de l'ordre de 25–35 %. La densité relative du cermet, sa dureté et son comportement tribologique, dépendront de la nature de l'addition dans les mélanges de départ. Porous TiC-Ni based cermets were obtained by dispersion of carbides, oxides or borides particles in a nickel matrix thanks to the thermal explosion technique realized under a load of 20 MPa. The combustion of active mixtures (Ti-C-Ni-An where An = Al2O3, MgO, SiC, TiB2 or WC based on the titanium carbide reaction synthesis (ΔHf = −184 kJ/mol, generates porous complex cermets. After the thermal explosion, a short maintenance under load at 1373 K of the combustion product, allows at the same time the cermets welding on a carbon steel substrate. The obtained cermets under these conditions preserve a porosity of about 25–35%. The relative density, hardness and tribological behaviour of the complex cermets depend on the additions nature (An in the starting mixtures.

  20. Dosimetry and optimization in digital radiography based on the detail contrast resolution

    Energy Technology Data Exchange (ETDEWEB)

    Gomes B, W. O. [Instituto Federal da Bahia, Rua Emidio dos Santos s/n, Barbalho 40301-015, Salvador de Bahia (Brazil); Gomes de C, A., E-mail: wilsonottobatista@gmail.com [Secretaria de Saude do Estado da Bahia, Salvador de Bahia (Brazil)

    2016-10-15

    In digital radiography, computed radiography systems (CR) and portable panels a-Si (DR) are adapted to equipment previously used for the system screen / film. Therefore it maintains the characteristics as grid, filtration, yield, etc. Otherwise, the systems dedicated with a-Si panels (DR), are designed to operate with these image receptors. The ability to detect in low contrast details is reduced for all systems with increasing ratio of scattered radiation / primary radiation. In this context there is a need to acquire experience and adjust exposure protocols to ensure the quality of the image with maintaining kerma values in the surface as low as possible. The contrast resolution is defined as the ability of the system to distinguish similar degrees of attenuation of the object and is a parameter used to maintain the quality index and comparison between different systems. The protocols were: chest (90 and 102 kV with the range of 2-20 m As) and abdomen (80 kV in the range of 10-80 m As). Kerma values were evaluated with a solid state sensors. Based on analysis of these curves C-D, which identified the technique would imply a lower kerma input surface while maintaining image quality from the point of view of contrast-detail resolution. The results show that the IQFinv varies little throughout the range of m As, while the value of kerma varies linearly with in m As. Also, the complete analysis of the curves indicate that there was an increase in the definition of detail with increasing m As. The conclusion is that, in the transition phase of the new receivers are needed to assess and adjust practiced protocols to ensure the quality index of the image taking into account aspects of radiation protection of the patient. And even with digital technology, good radiographic technique should be practiced. (Author)

  1. Le partenariat mondial sur les données ouvertes pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les données ouvertes favorisent le changement. Au Brésil, au Népal et au Nigeria, certaines personnes utilisent les données publiquement accessibles sur le budget gouvernemental pour repérer et combattre la corruption. Des analystes de données et des développeurs en TI d'autres pays en développement améliorent ...

  2. Analyse anthropotechnique du port de charge sur la tete au Benin ...

    African Journals Online (AJOL)

    Les difficultés auxquelles les femmes marchandes ambulantes de Porto-Novo sont confrontées sont dues à la qualité et à l'efficacité des moyens et des techniques de transport de leurs marchandises dans les marchés. En effet, ces femmes ont choisi de porter leurs marchandises sur la tête à travers les cinq grands ...

  3. Oxidation films morphology; Sur la morphologie des pellicules d'oxydation

    Energy Technology Data Exchange (ETDEWEB)

    Paidassi, J [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    After studying the oxidation of several pure polyvalent metals (Fe, Cu, Mn, Ni, U) and of their oxides at high temperature and atmospheric pressure, the author suggests how to modify the usual representation of the oxide film (a piling of different oxide layers, homogeneous on a micrographic scale with a equi-axial crystallisation, free of mechanical tensions, with flat boundary surfaces) to have it nearer to reality. In this first part, the author exposes the study of the real micrographic structure of the oxidation film and gives examples of precipitation in the oxides during the cooling of the oxidised sample. (author) [French] En se basant sur les etudes qu'il a faites sur l'oxydation aux temperatures elevees et a la pression atmospherique de quelques metaux purs a valences multiples (Fe, Cu, Mn, Ni, U), et de leurs oxydes, l'auteur suggere comment le schema qui representerait la pellicule comme etant une superposition de diverses couches d'oxydes, homogenes micrographiquement, a cristallisations equiaxes, depourvues de tensions mecaniques et separees par des interfaces plans, doit etre modifie pour s'ajuster a la realite. Dans cette premiere partie, l'auteur etudie la structure micrographique reelle des pellicules d'oxydation et donne des exemples de precipitation dans les oxydes au cours du refroidissement des echantillons oxydes. (auteur)

  4. Hydrogel based tissue mimicking phantom for in-vitro ultrasound contrast agents studies.

    Science.gov (United States)

    Demitri, Christian; Sannino, Alessandro; Conversano, Francesco; Casciaro, Sergio; Distante, Alessandro; Maffezzoli, Alfonso

    2008-11-01

    Ultrasound medical imaging (UMI) is the most widely used image analysis technique, and often requires advanced in-vitro set up to perform morphological and functional investigations. These studies are based on contrast properties both related to tissue structure and injectable contrast agents (CA). In this work, we present a three-dimensional structure composed of two different hydrogels reassembly the microvascular network of a human tissue. This phantom was particularly suitable for the echocontrastographic measurements in human microvascular system. This phantom has been characterized to present the acoustic properties of an animal liver, that is, acoustic impedance (Z) and attenuation coefficient (AC), in UMI signal analysis in particular; the two different hydrogels have been selected to simulate the target organ and the acoustic properties of the vascular system. The two hydrogels were prepared starting from cellulose derivatives to simulating the target organ parenchyma and using a PEG-diacrylate to reproduce the vascular system. Moreover, harmonic analysis was performed on the hydrogel mimicking the liver parenchyma hydrogel to evaluate the ultrasound (US) distortion during echographic measurement. The phantom was employed in the characterization of an experimental US CA. Perfect agreement was found when comparing the hydrogel acoustical properties materials with the corresponding living reference tissues (i.e., vascular and parenchimal tissue).

  5. Physique du deuil. Note sur la dernière vie de Roland Barthes

    Directory of Open Access Journals (Sweden)

    Maïté Snauwaert

    2013-03-01

    Full Text Available Les remarques sur la tenue de la maison et du corps dans le quotidien domestique, conçue comme une éthique de la fidélité à la mère récemment disparue, apparaissent dans l’écrit privé du Journal de deuil de Roland Barthes comme un écho des observations faites dans le cours sur La préparation du roman. Participant d’une physique du vivre et de l’habiter qui met l’accent sur l’entretien quotidien du lieu, le silence et la difficulté de tout voyage, les « notations » du journal rendent compte de la condensation dans le corps de l’épreuve du deuil, et de la prise de conscience d’un dernier âge de la vie.In the personal writings of Journal de deuil, Roland Barthes’ remarks regarding the maintenance of the home and body are conceived of as an ethic of faithfulness to his recently deceased mother. They are considered in this article as an echo to the observations he makes during his lectures in the course La préparation du roman. Both emphasize the physicality of everyday life and the role played by one’s relationship to the home. By stressing the necessity of silence and the difficulties of leaving “the apartment”, the brief “notations” in the diary translate the physical concentration of the mourning experience, as well as the emergent understanding of a final stage of life.

  6. Attribution d'un financement de base au Global Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Attribution d'un financement de base au Global Development Network (GDN) - phase II. La Banque mondiale a lancé le Global Development Network (GDN) en 1999 en s'appuyant sur le principe que des recherches bien menées sur les politiques et appliquées comme il se doit peuvent accélérer le processus de ...

  7. Influence de l'occupation des terres sur la dynamique des ...

    African Journals Online (AJOL)

    L'objectif de la présente étude est d'évaluer l'impact de mise en culture, des pâturages, des jachères et l'influence des villages sur la dynamique des communautés végétales de la commune de ..... mais il n'y a que peu de recrutement. Au-delà de cinq ans, taille et phytovolume diminuent, témoignant du vieillissement de la ...

  8. Perspectives queer et féministes pour un regard critique sur l’intimité dans les médias numériques

    OpenAIRE

    Gauthier, Maude; Mercier, Élisabeth

    2017-01-01

    De quelles manières l’intimité se conçoit-elle aujourd’hui sur Internet et sur les réseaux socionumériques ? Comment les médias numériques rendent-ils possible et interviennent-ils sur différentes formes d’intimité ? Comment ces médias participent-ils à (re)définir la notion même d’intimité, ses domaines et ses frontières ? Ce dossier thématique propose d’explorer les expériences vécues et les discours sociaux autour de l’intimité dans le contexte numérique. Plus spécifiquement, c’est à parti...

  9. Comparative evaluation of SUV, tumor-to-blood standard uptake ratio (SUR), and dual time point measurements for assessment of the metabolic uptake rate in FDG PET.

    Science.gov (United States)

    Hofheinz, Frank; Hoff, Jörg van den; Steffen, Ingo G; Lougovski, Alexandr; Ego, Kilian; Amthauer, Holger; Apostolova, Ivayla

    2016-12-01

    We have demonstrated recently that the tumor-to-blood standard uptake ratio (SUR) is superior to tumor standardized uptake value (SUV) as a surrogate of the metabolic uptake rate K m of fluorodeoxyglucose (FDG), overcoming several of the known shortcomings of the SUV approach: excellent linear correlation of SUR and K m from Patlak analysis was found using dynamic imaging of liver metastases. However, due to the perfectly standardized uptake period used for SUR determination and the comparatively short uptake period, these results are not automatically valid and applicable for clinical whole-body examinations in which the uptake periods (T) are distinctly longer and can vary considerably. Therefore, the aim of this work was to investigate the correlation between SUR derived from clinical static whole-body scans and K m-surrogate derived from dual time point (DTP) measurements. DTP (18)F-FDG PET/CT was performed in 90 consecutive patients with histologically proven non-small cell lung cancer (NSCLC). In the PET images, the primary tumor was delineated with an adaptive threshold method. For determination of the blood SUV, an aorta region of interest (ROI) was delineated manually in the attenuation CT and transferred to the PET image. Blood SUV was computed as the mean value of the aorta ROI. SUR values were computed as ratio of tumor SUV and blood SUV. SUR values from the early time point of each DTP measurement were scan time corrected to 75 min postinjection (SURtc). As surrogate of K m, we used the SUR(T) slope, K slope, derived from DTP measurements since it is proportional to the latter under the given circumstances. The correlation of SUV and SURtc with K slope was investigated. The prognostic value of SUV, SURtc, and K slope for overall survival (OS) and progression-free survival (PFS) was investigated with univariate Cox regression in a homogeneous subgroup (N=31) treated with primary chemoradiation. Correlation analysis revealed for both, SUV and SURtc, a

  10. X-ray Phase Contrast analysis - Digital wavefront development

    International Nuclear Information System (INIS)

    Idir, Mourad; Potier, Jonathan; Fricker, Sebastien; Snigirev, Anatoly; Snigireva, Irina; Modi, M. H.

    2010-01-01

    Optical schemes that enable imaging of the phase shift produced by an object have become popular in the x-ray region, where phase can be the dominant contrast mechanism. The propagation-based technique consists of recording the interference pattern produced by choosing one or several sample-to-detector distances. Pioneering studies, carried out making use of synchrotron radiation, demonstrated that this technique results in a dramatic increase of image contrast and detail visibility, allowing the detection of structures invisible with conventional techniques. An experimental and theoretical study of in-line hard x-ray phase-contrast imaging had been performed. The theoretical description of the technique is based on Fresnel diffraction. As an illustration of the potential of this quantitative imaging technique, high-resolution x-ray phase contrast images of simple objects will be presented.

  11. Study on the uptake and distribution of gadolinium based contrast agents in biological samples using laser ablation with inductively coupled plasma mass spectroscopy

    International Nuclear Information System (INIS)

    Lingott, Jana

    2016-01-01

    Gadolinium based contrast agents are used for magnetic resonance imaging. After their excretion by medicated patients they reach surface water passing waste water treatment plants where they are not removed sufficiently. The behavior of the contrast agents in the environment and the interaction with organisms was investigated in this work due to the toxicity of the free Gd 3+ ion and the associated risks, such as accumulation in the human food chain. In this work, the two elemental analytical imaging methods laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and synchrotron radiation X-ray fluorescence analysis (SRXRF) have been used to investigate the uptake, distribution, and excretion of Gd-based contrast agents by various biological systems. Both methods were analytically characterized and compared for this application. The detection limits of gadolinium were determined under optimized conditions by LA-ICP-MS and SRXRF. With calibration by remains of dried elemental standard droplets detection limits of 0.78 pg absolute amount of gadolinium (LA-ICP-MS), respectively 89 pg (SRXRF) were reached. Based on filamentous algae as water plants the uptake and the excretion of Gd-based contrast agents were revealed. The dependence on concentration of the contrast agent in the exposition solution and the independence of temporal uptake within one to seven days were studied for duckweed. By LA-ICP-MS gadolinium was quantified in a leaf of cress plant. The verification of the results was performed by SRXRF and ICP-MS after digestion. Furthermore, the uptake and distribution of Gd-based contrast agents in higher organisms (water flea) were observed. The exact location of gadolinium was resolved by three-dimensional μ-computed tomography by the comparison of an exposed with a Gd-free water flea. In all studies, gadolinium was detected in the investigated exposed model organisms. It can be concluded that the contrast agents were taken from the environment.

  12. Rapports 2016-2017 sur les frais de voyage pour Sophie d'Amours ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s). 2016-07-06. Destination(s). Ottawa. Billet d'avion. 866.40 $. Frais de transport au sol ou autrement. 83.50 $. Frais de logement. 0.00 $. Repas et frais divers. 84.53 $. Autre frais. 0.00 $. Total. 1 034.43 $. Commentaires. Rapports 2016-2017 sur les frais de voyage pour Sophie d'Amours, gouverneur.

  13. A meta-analysis of the price elasticity of gasoline demand. A SUR approach

    Energy Technology Data Exchange (ETDEWEB)

    Brons, Martijn; Rietveld, Piet [Department of Spatial Economics, Vrije Universiteit, De Boelelaan 1105, 1081 HV Amsterdam (Netherlands); Tinbergen Institute Amsterdam (TIA), Roetersstraat 31, 1018 WB Amsterdam (Netherlands); Nijkamp, Peter [Department of Spatial Economics, Vrije Universiteit, De Boelelaan 1105, 1081 HV Amsterdam (Netherlands); Tinbergen Institute Amsterdam (TIA), Roetersstraat 31, 1018 WB Amsterdam (Netherlands); The Netherlands Organisation of Scientific Research (NWO), postbus 93138 - 2509 AC Den Haag (Netherlands); Pels, Eric [Department of Spatial Economics, Vrije Universiteit, De Boelelaan 1105, 1081 HV Amsterdam (Netherlands)

    2008-09-15

    Automobile gasoline demand can be expressed as a multiplicative function of fuel efficiency, mileage per car and car ownership. This implies a linear relationship between the price elasticity of total fuel demand and the price elasticities of fuel efficiency, mileage per car and car ownership. In this meta-analytical study we aim to investigate and explain the variation in empirical estimates of the price elasticity of gasoline demand. A methodological novelty is that we use the linear relationship between the elasticities to develop a meta-analytical estimation approach based on a Seemingly Unrelated Regression (SUR) model with Cross Equation Restrictions. This approach enables us to combine observations of different elasticities and thus increase our sample size. Furthermore, it allows for a more detailed interpretation of our meta-regression results. The empirical results of the study demonstrate that the SUR approach leads to more precise results (i.e., lower standard errors) than a standard meta-analytical approach. We find that, with mean short run and long run price elasticities of - 0.34 and - 0.84, respectively, the demand for gasoline is not very price sensitive. Both in the short and the long run, the impact of a change in the gasoline price on demand is mainly driven by responses in fuel efficiency and mileage per car and to a slightly lesser degree by changes in car ownership. Furthermore, we find that study characteristics relating to the geographic area studied, the year of the study, the type of data used, the time horizon and the functional specification of the demand equation have a significant impact on the estimated value of the price elasticity of gasoline demand. (author)

  14. A meta-analysis of the price elasticity of gasoline demand. A SUR approach

    International Nuclear Information System (INIS)

    Brons, Martijn; Rietveld, Piet; Nijkamp, Peter; Pels, Eric

    2008-01-01

    Automobile gasoline demand can be expressed as a multiplicative function of fuel efficiency, mileage per car and car ownership. This implies a linear relationship between the price elasticity of total fuel demand and the price elasticities of fuel efficiency, mileage per car and car ownership. In this meta-analytical study we aim to investigate and explain the variation in empirical estimates of the price elasticity of gasoline demand. A methodological novelty is that we use the linear relationship between the elasticities to develop a meta-analytical estimation approach based on a Seemingly Unrelated Regression (SUR) model with Cross Equation Restrictions. This approach enables us to combine observations of different elasticities and thus increase our sample size. Furthermore, it allows for a more detailed interpretation of our meta-regression results. The empirical results of the study demonstrate that the SUR approach leads to more precise results (i.e., lower standard errors) than a standard meta-analytical approach. We find that, with mean short run and long run price elasticities of - 0.34 and - 0.84, respectively, the demand for gasoline is not very price sensitive. Both in the short and the long run, the impact of a change in the gasoline price on demand is mainly driven by responses in fuel efficiency and mileage per car and to a slightly lesser degree by changes in car ownership. Furthermore, we find that study characteristics relating to the geographic area studied, the year of the study, the type of data used, the time horizon and the functional specification of the demand equation have a significant impact on the estimated value of the price elasticity of gasoline demand. (author)

  15. Is the transport of a gadolinium-based contrast agent decreased in a degenerated or aged disc? A post contrast MRI study.

    Directory of Open Access Journals (Sweden)

    Marta Tibiletti

    Full Text Available A post contrast magnetic resonance imaging study has been performed in a wide population of low back pain patients to investigate which radiological and phenotypic characteristics influence the penetration of the contrast agent in lumbar discs in vivo. 37 patients affected by different pathologies (disc herniation, spondylolisthesis, foraminal stenosis, central canal stenosis were enrolled in the study. The selected population included 26 male and 11 female subjects, with a mean age of 42.4 ± 9.3 years (range 18-60. Magnetic resonance images of the lumbar spine were obtained with a 1.5 T scanner (Avanto, Siemens, Erlangen, Germany with a phased-array back coil. A paramagnetic non-ionic contrast agent was injected with a dose of 0.4 ml/kg. T1-weighted magnetic resonance images were subsequently acquired at 5 time points, 5 and 10 minutes, 2, 4 and 6 hours after injection. Endplates presented clear enhancement already 5 minutes after injection, and showed an increase in the next 2 hours followed by a decrease. At 5 and 10 minutes, virtually no contrast medium was present inside the intervertebral disc; afterwards, enhancement significantly increased. Highly degenerated discs showed higher enhancement in comparison with low and medium degenerated discs. Discs classified as Pfirrmann 5 showed a statistically significant higher enhancement than Pfirrmann 1, 2 and 3 at all time points but the first one, possibly due to vascularization. Disc height collapse and Modic changes significantly increased enhancement. Presence of endplate defects did not show any significant influence on post contrast enhancement, but the lack of a clear classification of endplate defects as seen on magnetic resonance scans may be shadowing some effects. In conclusion, disc height, high level of degeneration and presence of Modic changes are factors which increase post contrast enhancement in the intervertebral disc. The effect of age could not be demonstrated.

  16. Compactification de la Supergravite 10-D Sur les Varietes de Calabi-Yau

    Science.gov (United States)

    Gagnon, Michel

    Les varietes de Calabi-Yau permettent une description relativement simple et assez juste de la realite. Recemment, de nombreuses equipes de recherche s'y sont interessees, en particulier P. Candelas, A. M. Dale, C. A. Lutken et R. Schimmrigk (13) qui ont propose une liste de 7868 configurations distinctes. Toutefois, nous croyons que certaines des techniques qui sont exploitees pour construire cette liste ne sont pas suffisamment justifiees et ont pour effet de soustraire a nos investigations bon nombre de configurations potentiellement interessantes. Ainsi, nous produisons, sans utiliser ces techniques simplificatrices, une liste de 97360 configurations. Ensuite, dans le cadre des modeles a 4 generations, nous appliquons un ensemble de criteres, fondes sur les symetries discretes, pour delimiter le domaine des configurations phenomenologiquement viables. Finalement, apres avoir fixe notre choix sur une configuration particuliere, nous essayons de montrer tout l'interet physique des varietes de Calabi-Yau en exposant certains aspects de la phenomenologie a basse energie, notamment les nombres quantiques, les spectres fermioniques, la brisure intermediaire du groupe de jauge et la duree de vie du proton.

  17. Morphological rational operator for contrast enhancement.

    Science.gov (United States)

    Peregrina-Barreto, Hayde; Herrera-Navarro, Ana M; Morales-Hernández, Luis A; Terol-Villalobos, Iván R

    2011-03-01

    Contrast enhancement is an important task in image processing that is commonly used as a preprocessing step to improve the images for other tasks such as segmentation. However, some methods for contrast improvement that work well in low-contrast regions affect good contrast regions as well. This occurs due to the fact that some elements may vanish. A method focused on images with different luminance conditions is introduced in the present work. The proposed method is based on morphological transformations by reconstruction and rational operations, which, altogether, allow a more accurate contrast enhancement resulting in regions that are in harmony with their environment. Furthermore, due to the properties of these morphological transformations, the creation of new elements on the image is avoided. The processing is carried out on luminance values in the u'v'Y color space, which avoids the creation of new colors. As a result of the previous considerations, the proposed method keeps the natural color appearance of the image.

  18. determinants de l'adoption et impact des varietes ameliorees sur la ...

    African Journals Online (AJOL)

    ACSS

    C'est ainsi que la recherche a créé des nouvelles variétés ... La recherche en économie de la production agricole a montré que les taux d'adoption et les facteurs influençant la décision des agriculteurs d'adopter une technologie agricole varient fortement entre ..... des agriculteurs sur l'innovation sont fortement liées aux ...

  19. Rapport annuel au Parlement Loi sur l'Acces à l'information

    International Development Research Centre (IDRC) Digital Library (Canada)

    leonardi

    1 juil. 1983 ... recherche, la production, la programmation de l'ordinateur, la préparation, le support de substitution et la reproduction des différents documents. Les droits en vigueur sont précisés dans le Règlement sur l'accès à l'information. Seuls les droits de 5 $ exigibles au moment de la présentation des demandes.

  20. Las localidades menores del sur de Mar del Plata desde una perspectiva demogeográfica (1991-2001

    Directory of Open Access Journals (Sweden)

    Sofía Estela Ares

    2008-01-01

    Full Text Available En relación con el crecimiento demográfico de las localidades ubicadas al sur de Mar del Plata (Partido de General Pueyrredon el problema es establecer el aporte de los saldos vegetativos y de los saldos migratorios. Las bases de datos censales permiten la aproximación indirecta al comportamiento vegetativo; con respecto a las migraciones, no es posible calcular saldos de movilidad. Los resultados se obtuvieron mediante el procesamiento cuantitativo de datos censales y muestran un proceso de envejecimiento en las localidades mencionadas y la probable preeminencia del componente migratorio en el crecimiento demográfico.