WorldWideScience

Sample records for construction engineering research

  1. Duct Remediation Program: Engineered access research and construction

    International Nuclear Information System (INIS)

    Beckman, T.D.; Davis, M.M.; Karas, T.M.

    1992-01-01

    The Rocky Flats Plant, Duct Remediation mission concentrated on removing Plutonium Oxide from the process ductwork in the primary Plutonium processing facility. When possible, remediation took place from existing process gloveboxes. Fifteen locations were identified, however, that required accessing duct runs where no process gloveboxes existed. The building's second floor utility areas had many locations where long, inaccessible duct runs were prevalent. Consequently, an extensive program for design, procurement and construction was initiated to contain and isolate ducts for penetration when existing glovebox sites were not present

  2. Concrete construction engineering handbook

    CERN Document Server

    Nawy, Edward G

    2008-01-01

    Provides coverage of concrete construction engineering and technology. This work features discussions focusing on: the advances in engineered concrete materials; reinforced concrete construction; specialized construction techniques; and, design recommendations for high performance.

  3. [Research progress of co-culture system for constructing vascularized tissue engineered bone].

    Science.gov (United States)

    Fu, Weili; Xiang, Zhou

    2014-02-01

    To review the research progress of the co-culture system for constructing vascularized tissue engineered bone. The recent literature concerning the co-culture system for constructing vascularized tissue engineered bone was reviewed, including the selection of osteogenic and endothelial lineages, the design and surface modification of scaffolds, the models and dimensions of the co-culture system, the mechanism, the culture conditions, and their application progress. The construction of vascularized tissue engineered bone is the prerequisite for their survival and further clinical application in vivo. Mesenchymal stem cells (owning the excellent osteogenic potential) and endothelial progenitor cells (capable of directional differentiation into endothelial cell) are considered as attractive cell types for the co-culture system to construct vascularized tissue engineered bone. The culture conditions need to be further optimized. Furthermore, how to achieve the clinical goals of minimal invasion and autologous transplantation also need to be further studied. The strategy of the co-culture system for constructing vascularized tissue engineered bone would have a very broad prospects for clinical application in future.

  4. LOGISTICS RISK RESEARCH OF PREFABRICATED HOUSE CONSTRUCTION ENGINEERING BASED ON CREDIBILITY METHOD

    Directory of Open Access Journals (Sweden)

    Xiaoping Bai

    2017-07-01

    Full Text Available In recent years, the prefabricated house industry has rapid development,.Because of fewer suppliers, higher demand transport scheme and complex quality test, the risks of construction engineering logistics links are relatively high. Studying how to effectively evaluate the risks of construction engineering logistics links is significant. According to the characteristics of the prefabricated house construction engineering, we analyse the construction engineering logistics risks and use the combined weights method to determine the weight of indexes which contains both subjective and objective factors, to improve the scientific value and the validity of the assessment. Based on credibility measure method, a new logistics risk evaluation model in prefabricated housing is established to estimate the risk during making prefabricated house construction engineering. The presented model can avoid the subjectivity of selecting the membership function and solve the problem of how to comprehensively assess the construction engineering logistics risk in a certain extent.

  5. Visualization of construction engineering

    International Nuclear Information System (INIS)

    Okada, Hisako; Miura, Jun

    2000-01-01

    It is required for nuclear power plant construction to reduce construction cost and shorten construction period. An early and accurate construction planning including schedule coordination among the companies has recently become more important and it is possible to obtain necessary information for construction planning in early stage. In this situation, we have been developing a visualization system for construction engineering for nuclear power plants. This system has an interface with the existing Plant Layout 3D-CAD system and consists of three sub systems: (1) Scheduling and simulation system, (2) Yard planning system and (3) Scaffolding planning system. This paper describes overview of this system. This visualization system is very helpful for construction engineers to easily understand situation and environment around installation area, to easily plan a work sequence and confirm the planned schedule, and it is also effective for customers and workers to understand the planning. As a result, this visualization system enables safety and high quality construction. (author)

  6. How engineering facilitates construction

    International Nuclear Information System (INIS)

    Bailey, D.T.

    1976-01-01

    During a recent survey, construction personnel at jobsites were asked, ''what are the ten most unwanted construction problems.'' One reoccurring answer was design/construction incompatibility. In fact, many designs were impractical from a construction point of view. The reasons for this problem can be identified: Once construction begins, engineering is under intense pressure to issue new drawings to allow work to progress according to schedule. Other reasons may be the relative inexperience of the design personnel in construction, changes in design criteria and delays in receipt of supplier or client information. A description is presented of ways to solve this problem by obtaining construction expertise and input into the various phases and products of the engineering work

  7. Reduced analysis and confirmatory research on co-adaptability theoretical solution to conflicting events in construction engineering projects

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The co-adaptability theoretical solution to conflicting events in construction engineering projects has three problems. First, the transformation of constraint conditions of theoretical solution is very difficult in practical engineering applications; second, some coefficients are difficult to be determined; third, there are overfull circular arithmetic operations involved in it. To resolve these problems, a new method to reduce the theoretical solution complications is proposed. By analyzing the operating mechanism of theoretical solution model, redundancies in the theoretical solution can be eliminated, and the ISM mapping with the co-adaptability solution can be set up. Based on this approach, a procedure to solve practical conflicting events in construction projects is established by replacing characteristic variables with mathematic variables. The research results show that the procedure can replace the co-adaptability theoretical solution effectively and solve practical conflicting events in construction projects.

  8. A History of the U.S. Army Construction Engineering Research Laboratory (CERL) 1964-1985

    Science.gov (United States)

    1987-12-01

    This practice has continued to the present. Occasionally, the Corps’ applied research would trickle down to the general public, as in the case of...of this invention when applied to the construction of pipelines, nuclear reactors , and structures in general. 7 3 The ceramic anodes represented a...installation conditions - high fills shallow cover, various bedding , and back fill conditions. 2. Standard Design of Head Walls, End Walls and Wing

  9. Document management in engineering construction

    International Nuclear Information System (INIS)

    Liao Bing

    2008-01-01

    Document management is one important part of systematic quality management, which is one of the key factors to ensure the construction quality. In the engineering construction, quality management and document management shall interwork all the time, to ensure the construction quality. Quality management ensures that the document is correctly generated and adopted, and thus the completeness, accuracy and systematicness of the document satisfy the filing requirements. Document management ensures that the document is correctly transferred during the construction, and various testimonies such as files and records are kept for the engineering construction and its quality management. This paper addresses the document management in the engineering construction based on the interwork of the quality management and document management. (author)

  10. Study on engineering technologies in the Mizunami Underground Research Laboratory (FY 2015). Development of design and construction planning and countermeasure technologies (Contract research)

    International Nuclear Information System (INIS)

    Toguri, Satohito; Kobayashi, Shinji; Tsuji, Masakuni; Yahagi, Ryoji; Yamada, Toshiko; Matsui, Hiroya; Mikake, Shinichiro; Aoyagi, Yoshiaki; Sato, Toshinori

    2017-03-01

    The study on engineering technology in the Mizunami Underground Research Laboratory (MIU) project roughly consists of (1)development of design and construction planning technologies, (2)development of construction technology, (3)development of countermeasure technology, (4)development of technology for security, and (5) development of technologies regarding restoration and mitigating of the excavation effect. So far, the verification of the initial design based on the data obtained during excavation was mainly conducted as a research in the Construction Phase, also the countermeasure technologies to control groundwater inflow were examined as a research in the Operation Phase. In FY2015, as a part of the important issues on the research program, “Development of countermeasure technologies for reducing groundwater inflow” in the Japan Atomic Energy Agency 3rd Midterm Plan, water-tight grouting method has been developed. Grouting methods utilized in the MIU were evaluated and the post-excavation grouting at the -500m Access/Research Gallery-South was planned based on these evaluation results. Also, technology development from the viewpoint of geological disposal was summarized, and information on the alternative method to the grouting method was collected and organized. (author)

  11. Ice Engineering Research Area

    Data.gov (United States)

    Federal Laboratory Consortium — Refrigerated Physical Modeling of Waterways in a Controlled EnvironmentThe Research Area in the Ice Engineering Facility at the Cold Regions Research and Engineering...

  12. Computer aided system engineering for space construction

    Science.gov (United States)

    Racheli, Ugo

    1989-01-01

    This viewgraph presentation covers the following topics. Construction activities envisioned for the assembly of large platforms in space (as well as interplanetary spacecraft and bases on extraterrestrial surfaces) require computational tools that exceed the capability of conventional construction management programs. The Center for Space Construction is investigating the requirements for new computational tools and, at the same time, suggesting the expansion of graduate and undergraduate curricula to include proficiency in Computer Aided Engineering (CAE) though design courses and individual or team projects in advanced space systems design. In the center's research, special emphasis is placed on problems of constructability and of the interruptability of planned activity sequences to be carried out by crews operating under hostile environmental conditions. The departure point for the planned work is the acquisition of the MCAE I-DEAS software, developed by the Structural Dynamics Research Corporation (SDRC), and its expansion to the level of capability denoted by the acronym IDEAS**2 currently used for configuration maintenance on Space Station Freedom. In addition to improving proficiency in the use of I-DEAS and IDEAS**2, it is contemplated that new software modules will be developed to expand the architecture of IDEAS**2. Such modules will deal with those analyses that require the integration of a space platform's configuration with a breakdown of planned construction activities and with a failure modes analysis to support computer aided system engineering (CASE) applied to space construction.

  13. Designing requirements engineering research

    NARCIS (Netherlands)

    Wieringa, Roelf J.; Heerkens, Johannes M.G.

    2007-01-01

    Engineering sciences study different topics than natural sciences, and utility is an essential factor in choosing engineering research problems. But despite these differences, research methods for the engineering sciences are no different than research methods for any other kind of science. At most

  14. Construction Management of Electromechanical Engineering Project in Petrochemical Construction

    Directory of Open Access Journals (Sweden)

    Xi Tao

    2017-03-01

    Full Text Available Petrochemical industry as a basic industry, occupies a pivotal position in the national economy, with the continuous development of science and technology, electromechanical automation in the petrochemical industry has been widely used to save a lot of labor but also greatly improve the oil Chemical industry production efficiency. Therefore, in the construction of petrochemical industry, mechanical and electrical engineering as part of it. It plays a vital role. Petrochemical industry with the production of high temperature and high pressure and flammable and explosive gas, can strengthen the construction of mechanical and electrical engineering specialization and construction management of scientific, has become the relationship between the smooth development of mechanical and electrical engineering and engineering quality of the key, A direct impact on the petrochemical construction of the overall construction quality. To this end, it is necessary for the construction of petrochemical construction of electromechanical engineering construction management to promote the construction of mechanical and electrical engineering management level gradually increased. This article on the machine Electric engineering project construction management were discussed with a view to the petrochemical construction in the relevant aspects of the need to provide reference for reference.

  15. Vascularization of soft tissue engineering constructs

    DEFF Research Database (Denmark)

    Pimentel Carletto, Rodrigo

    with mechanical properties in the range of soft tissues has not been fully achieved. My project focused on the fabrication and the active perfusion of hydrogel constructs with multi-dimensional vasculature and controlled mechanical properties targeting soft tissues. Specifically, the initial part of the research...... nanotechnology-based paradigm for engineering vascularised liver tissue for transplantation”) and the Danish National Research Foundation and Villum Foundation’s Center for Intelligent Drug delivery and sensing Using microcontainers and Nanomechanics (Danish National Research Foundation (DNRF122)....

  16. Systems engineering research

    OpenAIRE

    Sahraoui , Abd-El-Kader; Buede , Dennis ,; Sage , Andrew ,

    2008-01-01

    International audience; In this paper, we propose selected research topics that are believed central to progress and growth in the application of systems engineering (SE). As a professional activity, and as an intellectual activity, systems engineering has strong links to such associated disciplines as decision analysis, operation research, project management, quality management, and systems design. When focussing on systems engineering research, we should distinguish between subjects that ar...

  17. Priorities in Construction IT Research

    DEFF Research Database (Denmark)

    Gaarslev, Axel

    1999-01-01

    Gives the results of a survey of the use and needs of research in IT in relation to construction......Gives the results of a survey of the use and needs of research in IT in relation to construction...

  18. Teaching engineering design research

    DEFF Research Database (Denmark)

    Blessing, Lucienne; Andreasen, Mogens Myrup

    2005-01-01

    The importance og engineering design as an industrial activity, and the increasingly complex and dynamic context in which it takes place, has led to the wish to improve the effectiveness and efficiency of engineering design in practice as well as in education. Although attempts have been made...... to improve design for centuries, it was not until well in the second half of the 20th century that engineering design became a research topic (see pahl and Beitz (1996), Heymann (2004) for historical overviews). Engineering research, such as research into thermodynamics, mechanics and materials, has a much...... by PhD students. This has created the demand for a clear, efficient way of learning the crafmanship of doing design research, a demand which is in strong contrast to the state of design research in general. This article reflects the authors' efforts in running a summer school om engineering design...

  19. Vascularization of soft tissue engineering constructs

    DEFF Research Database (Denmark)

    Pimentel Carletto, Rodrigo

    nanotechnology-based paradigm for engineering vascularised liver tissue for transplantation”) and the Danish National Research Foundation and Villum Foundation’s Center for Intelligent Drug delivery and sensing Using microcontainers and Nanomechanics (Danish National Research Foundation (DNRF122).......Vascularization is recognized to be the biggest challenge for the fabrication of tissues and finally, organs in vitro. So far, several fabrication techniques have been proposed to create a perfusable vasculature within hydrogels, however, the vascularization and perfusion of hydrogels...... with mechanical properties in the range of soft tissues has not been fully achieved. My project focused on the fabrication and the active perfusion of hydrogel constructs with multi-dimensional vasculature and controlled mechanical properties targeting soft tissues. Specifically, the initial part of the research...

  20. Managing engineering to meet construction requirements

    International Nuclear Information System (INIS)

    Martin, D.F.; Houchen, J.D.

    1976-01-01

    The San Onofre Units 2 and 3 Project schedule is compared with Bechtel's Generic Nuclear Power Plant schedule. This comparison shows that the major delays experienced on the San Onofre Project have resulted from the regulatory process. To date, Engineering has met Construction's requirements and the Project has not experienced any Engineering related delays. The San Onofre Project has been faced with many uncertainties, such as limited site area, high seismic design criteria, new and changing Federal and State regulations, shifts in supplier market conditions and unpredictable supplier performance. Each of these uncertainties has impacted the Engineering effort and jeopardized project schedule goals. The SCE-Bechtel Engineering Management team has acted to mitigate the impact of these uncertainties through use of a cost trend program, simplification of SCE-Bechtel interfaces, close Engineering-Construction coordination, the use of task forces to handle critical supplier problems and the use of additional Engineering personnel, etc. so that Construction requirements have been met

  1. Evaluation of Research in Engineering Science in Norway

    DEFF Research Database (Denmark)

    Van Brussel, Hendrik Van Brussel; Lindberg, Bengt; Cederwall, Klas

    This report presents the conclusions of Panel 1: Construction engineering, Production and Operation. The Research Council of Norway (NFR) appointed three expert panels to evaluate Research in Engineering Science in Norway .......This report presents the conclusions of Panel 1: Construction engineering, Production and Operation. The Research Council of Norway (NFR) appointed three expert panels to evaluate Research in Engineering Science in Norway ....

  2. Construction engineering inspection direct cost survey.

    Science.gov (United States)

    2014-07-01

    The objective of the study was to provide a rationale to Georgia Department of Transportation : (GDOT) for Direct Costs in terms of salary and wages charged by qualified independent : contractors performing Construction Engineering Inspection (CEI) s...

  3. Engineering Accomplishments in the Construction of NCSX

    International Nuclear Information System (INIS)

    G. H. Neilson; P.J. Heitzenroeder; B.E. Nelson; W.T. Reiersen; A. Brooks; T.G. Brown; J.H. Chrzanowski; M.J. Cole; F. Dahlgren; T. Dodson; L.E. Dudek; R.A. Ellis; H.M. Fan; P.J. Fogarty; K.D. Freudenberg; P.L. Goranson; J.H. Harris; M.R. Kalish; G. Labik; J.F. Lyon; N. Pomphrey; C.D. Priniski; S. Raftopoulos; D.J. Rej; W.R. Sands; R.T. Simmons; B.E. Stratton; R.L. Strykowsky; M.E. Viola; D.E. Williamson; M.C. Zarnstorff

    2008-01-01

    The National Compact Stellarator Experiment (NCSX) was designed to test a compact, quasiaxisymmetric stellarator configuration. Flexibility and accurate realization of its complex 3D geometry were key requirements affecting the design and construction. While the project was terminated before completing construction, there were significant engineering accomplishments in design, fabrication, and assembly. The design of the stellarator core device was completed. All of the modular coils, toroidal field coils, and vacuum vessel sectors were fabricated. Critical assembly steps were demonstrated. Engineering advances were made in the application of CAD modeling, structural analysis, and accurate fabrication of complex-shaped components and subassemblies. The engineering accomplishments of the project are summarized

  4. Engineering development in nuclear power plant construction

    International Nuclear Information System (INIS)

    Guenther, P.

    1979-01-01

    Proceeding from the up-to-now experience in the erection of nuclear power stations, especially of the first and second unit of the Greifswald nuclear power plant, the following essential aspects of the development of constructional engineering are discussed: (1) constructional features and criteria, (2) organizational management, (3) current status and problems in prelimary operations, and (4) possibilities of further expenditure reductions in constructing nuclear power stations

  5. Construct Measurement in Management Research

    DEFF Research Database (Denmark)

    Nielsen, Bo Bernhard

    2014-01-01

    Far too often do management scholars resort to crude and often inappropriate measures of fundamental constructs in their research; an approach which calls in question the interpretation and validity of their findings. Scholars often legitimize poor choices in measurement with a lack of availability......, this research note raises important questions about the use of proxies in management research and argues for greater care in operationalizing constructs with particular attention to matching levels of theory and measurement....

  6. The in-situ experiment for performance confirmation of engineered barrier system at Horonobe Underground Research Laboratory. Examination of backfill material using muck from URL construction

    International Nuclear Information System (INIS)

    Nakayama, Masashi; Ohno, Hirokazu; Tanai, Kenji; Fujita, Tomoo; Sugita, Yutaka

    2016-06-01

    The Horonobe Underground Research Laboratory (URL) Project has being pursued by Japan Atomic Energy Agency (JAEA) to enhance the reliability of relevant disposal technologies through investigations of the deep geological environment within the host sedimentary formation at Horonobe, northern Hokkaido. The URL Project consists of two major research areas, “Geoscientific Research” and “Research and Development on Geological Disposal Technologies”, and proceeds in three overlapping phases, “Phase I: Surface-based investigations”, “Phase II: Investigations during tunnel excavation” and “Phase III: Investigations in the underground facilities”, over a period of around 20 years. Phase III investigation was started in 2010 fiscal year. The in-situ experiment for performance confirmation of engineered barrier system (EBS experiment) was prepared from 2013 to 2014 fiscal year at G.L.-350m gallery (Niche No.4), and heating by electric heater in simulated overpack started in January, 2015. One of objectives of the experiment is acquiring data concerned with Thermal – Hydrological – Mechanical – Chemical (THMC) coupled behavior. These data will be used in order to confirm the performance of engineered barrier system. In EBS experiment, the backfill material using mixture of bentonite and muck from Horonobe URL construction was used for backfilling a part of Niche No.4. This report shows the results of properties of the backfill material, confirmation test of compaction method and making backfill material block, and so on. From these results, it was confirmed that the backfill material would satisfy target value of the permeability and the swelling pressure. (author)

  7. Optimization and control methods in industrial engineering and construction

    CERN Document Server

    Wang, Xiangyu

    2014-01-01

    This book presents recent advances in optimization and control methods with applications to industrial engineering and construction management. It consists of 15 chapters authored by recognized experts in a variety of fields including control and operation research, industrial engineering, and project management. Topics include numerical methods in unconstrained optimization, robust optimal control problems, set splitting problems, optimum confidence interval analysis, a monitoring networks optimization survey, distributed fault detection, nonferrous industrial optimization approaches, neural networks in traffic flows, economic scheduling of CCHP systems, a project scheduling optimization survey, lean and agile construction project management, practical construction projects in Hong Kong, dynamic project management, production control in PC4P, and target contracts optimization.   The book offers a valuable reference work for scientists, engineers, researchers and practitioners in industrial engineering and c...

  8. Empirical Research In Engineering Design

    DEFF Research Database (Denmark)

    Ahmed, Saeema

    2007-01-01

    Increasingly engineering design research involves the use of empirical studies that are conducted within an industrial environment [Ahmed, 2001; Court 1995; Hales 1987]. Research into the use of information by designers or understanding how engineers build up experience are examples of research...... of research issues. This paper describes case studies of empirical research carried out within industry in engineering design focusing upon information, knowledge and experience in engineering design. The paper describes the research methods employed, their suitability for the particular research aims...

  9. Engine Environment Research Facility (EERF)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: This facility supports research and development testing of the behavior of turbine engine lubricants, fuels and sensors in an actual engine environment....

  10. Materials Engineering Research Facility (MERF)

    Data.gov (United States)

    Federal Laboratory Consortium — Argonne?s Materials Engineering Research Facility (MERF) enables engineers to develop manufacturing processes for producing advanced battery materials in sufficient...

  11. Global Journal of Engineering Research

    African Journals Online (AJOL)

    The Global Journal of Engineering Research is aimed at promoting research in all areas of Engineering Research including Mechanical, Civil, Electrical, Chemical, Electronics, Geological etc. Visit the Global Journal Series website here: http://www.globaljournalseries.com/ ...

  12. Framework for systems engineering research

    CSIR Research Space (South Africa)

    Erasmus, L

    2013-08-01

    Full Text Available In this paper a framework is proposed to perform systems engineering research within South Africa. It is proposed that within the reference of the National Research Foundation (NRF) classification of research, systems engineering is a Field...

  13. Cryopreservation of tissue engineered constructs for bone.

    Science.gov (United States)

    Kofron, Michelle D; Opsitnick, Natalie C; Attawia, Mohamed A; Laurencin, Cato T

    2003-11-01

    The large-scale clinical use of tissue engineered constructs will require provisions for its mass availability and accessibility. Therefore, it is imperative to understand the effects of low temperature (-196 degrees C) on the tissue engineered biological system. Initial studies used samples of the osteoblast-like cell line (SaOS-2) adhered to a two-dimensional poly(lactide-co-glycolide) thin film (2D-PLAGA) or a three-dimensional poly(lactide-co-glycolide) sintered microsphere matrix (3D-PLAGA) designed for bone tissue engineering. Experimental samples were tested for their ability to maintain cell viability, following low temperature banking for one week, in solutions of the penetrating cryoprotective agents, dimethylsulfoxide (DMSO), ethylene glycol, and glycerol. Results indicated the DMSO solution yielded the greatest percent cell survival for SaOS-2 cells adhered to both the 2D- and 3D-PLAGA scaffolds; therefore, DMSO was used to cryopreserve mineralizing primary rabbit osteoblasts cells adhered to 2D-PLAGA matrices for 35 days. Results indicated retention of the extracellular matrix architecture as no statistically significant difference in the pre- and post-thaw mineralized structures was measured. Percent cell viability of the mineralized constructs following low temperature storage was approximately 50%. These are the first studies to address the issue of preservation techniques for tissue engineered constructs. The ability to successfully cryopreserve mineralized tissue engineered matrices for bone may offer an unlimited and readily available source of bone-like materials for orthopaedic applications.

  14. Welding engineering manual for constructing engineers. Pt. 2

    International Nuclear Information System (INIS)

    Neumann, A.

    1986-01-01

    The manual is a real treasure trove of knowledge and experience for the statics expert, the constructing engineer, and the welding engineer, who have to do with design and dimensioning of welding engineering work for steel structures, bridges, boilers, vessels, and pipes. Many practical examples are given together with numerous data that provide helpful information for the task of technical and economic design and dimensioning. Determination of efficient and appropriate cross-sectional dimensions and materials is the main goal of the manual. Structural steel engineering and installations subject to monitoring and inspection such as boilers, pipings, pressure vessels, and nuclear installations are the subject fields dealt with in separate chapters. The dimensioning rules presented are based on the regulations and technical codes valid in the GDR and the FRG. The catalogue of technical rules of the FRG concerning structural steel engineering and installations as above are given in supplementary chapters. (orig./HP) [de

  15. ORNL engineering design and construction reengineering report

    Energy Technology Data Exchange (ETDEWEB)

    McNeese, L.E.

    1998-01-01

    A team composed of individuals representing research and development (R and D) divisions, infrastructure support organizations, and Department of Energy (DOE)-Oak Ridge Operations was chartered to reengineer the engineering, design, and construction (ED and C) process at Oak Ridge National Laboratory (ORNL). The team recognized that ED and C needs of both R and D customers and the ORNL infrastructure program have to be met to maintain a viable and competitive national laboratory. Their goal was to identify and recommend implementable best-in-class ED and C processes that will efficiently and cost-effectively support the ORNL R and D staff by being responsive to their programmatic and infrastructure needs. The team conducted process mapping of current and potential ED and C approaches, developed idealized versions of ED and C processes, and identified potential barriers to an efficient ED and C process. Eight subteams were assigned to gather information and to evaluate the significance of potential barriers through benchmarking, surveys, interviews, and reviews of key topical areas in order to determine whether the perceived barriers were real and important and whether they resulted from laws or regulations over which ORNL has no control.

  16. Civil Engineering Construction of Underground Works

    CERN Document Server

    Rammer, H

    1999-01-01

    For the first time at CERN, new shafts and caverns will be excavated inside a surface building. The LHC civil engineering construction for the ATLAS experiment has been designed such that the experimental hall will be completed to the extent that it can provide a secure, weatherproof and sound insulated covering to the shaft excavation area. The construction of the two access shafts and the experimental cavern will follow and will be carried out inside the building. This unconventional method of working allows the excavation of the Molasse rock in the dry, which is essential for this type of rock, and ensures reduced environmental pollution by noise and dust. The paper will present the technical infrastructure required for this particular construction method, explain its advantages and disadvantages, and compare it with a conventional method of underground excavations to be used on the same work site for the construction of the service cavern.

  17. Construction research needs in Europe

    DEFF Research Database (Denmark)

    1991-01-01

    fælles europæisk forsknings- og udviklingsstrategi for byggesektoren har det europæiske netværk af byggeforskningsinstitutter, ENBRI, sammenfattet de nationale forskningstemaer samt analyseret perspektiver og behov. Dette materiale er anvendt som diskussionsoplæg ved symposiet Construction research needs...

  18. Evolutionary algorithms and metaheuristics in civil engineering and Construction management

    CERN Document Server

    Greiner, David

    2015-01-01

    This book focuses on civil and structural engineering and construction management applications. The contributions constitute modified, extended and improved versions of research presented at the  minisymposium organized by the editors at the ECCOMAS conference on this topic in Barcelona 2014.

  19. Doublet III construction and engineering test

    International Nuclear Information System (INIS)

    Anon.

    1979-01-01

    Progress during FY-78 on the construction and operation of the Doublet III is reported. Detailed discussions about the installation and testing of various components and subsystems, including the B-coil, E-coil, F-coils and support structure, vacuum vessel, vacuum pumping system, limiter, thermal insulation blanket, control system, B-coil power system, E-coil power system, F-coil power system, and motor-generator, are presented. A brief review of the engineering test operation is given

  20. Adoption of value engineering: an attribute study for construction

    International Nuclear Information System (INIS)

    Shaikh, P.

    2015-01-01

    For economic reasons, engineers are compelled to explore low cost methods in construction industry to reduce the overall cost of a project. Research studies have been conducted in this regard throughout the world and value engineering is one of such approaches. Its effective use and applications reduces the project cost without compromising the project quality. Project cost, and efficient design alternatives can be identified using this technique, which will ultimately reduce the overall project cost. Client satisfaction, project reliability and quality can also be improved by the application of value engineering. It is also used for improving managerial performance, project schedule and reduced risks in a project. It is a powerful tool used to identify problems and recommend solutions. This paper highlights the importance of value engineering in general and with specific perspective of Construction Industry in Pakistan. Questionnaire based survey has been conducted by construction managers (i.e. project engineers, construction engineers, project managers, architects, etc.) through online web based system, as a result, random data sampling is achieved. The attributes are mapped to obtain goals for the project. The data has been analyzed through reliability and linear regression using SPSS while Z-Score and Average Index are conducted using MS Excel. The results showed that there is ample need to apply such techniques in initial phases of any project to get project benefits. (author)

  1. Application of value engineering technique in construction project

    International Nuclear Information System (INIS)

    Chen Changbing

    2003-01-01

    The author introduces how to apply the theories and methods of the value engineering in construction project. In the construction of a test device of the thermal hydrodynamic process, the authors have greatly reduced the construction cost and shortened the construction period by using the value engineering analyzing method. The application of value engineering in the project management is innovative. This practice indicates that the value engineering is important in many construction projects

  2. Workshop presentation: research guidelines for Construction Management

    Directory of Open Access Journals (Sweden)

    Marco Alvise Bragadin

    2013-10-01

    Full Text Available Nowadays the European economic system challenges the construction sector to take part to industrial recovery of western countries. In co-operation with the Construction Production research group of the Tampere University of of research about construction management tools and methods were detected. Research guidelines: 1 Construction management: tools and methods to manage construction projects 2 environmental impact of construction projects 3 construction management and safety 4 project procurement 5 construction management for major public works & complex projects

  3. NCSX Construction Progress and Research Plans

    International Nuclear Information System (INIS)

    Neilson, G.H.; Heitzenroeder, P.; Lyon, J.; Nelson, B.; Reiersen, W.; Zarnstorff, M.

    2005-01-01

    Stellarators use 3D plasma and magnetic field shaping to produce a steady-state disruption-free magnetic confinement configuration. Compact stellarators have additional attractive properties, quasi-symmetric magnetic fields and low aspect ratio. The National Compact Stellarator Experiment (NCSX) is being constructed at the Princeton Plasma Physics Laboratory (PPPL) in partnership with the Oak Ridge National Laboratory (ORNL) to test the physics of a high-beta compact stellarator with a low-ripple, tokamak-like magnetic configuration. The engineering challenges of NCSX stem from its complex geometry requirements. These issues are addressed in the construction project through manufacturing R and D and system engineering. As a result, the fabrication of the coil winding forms and vacuum vessel are proceeding in industry without significant technical issues, and preparations for winding the coils at PPPL are in place. Design integration, analysis, and dimensional control are functions provided by system engineering to ensure that the finished product will satisfy the physics requirements, especially accurate realization of the specified coil geometries. After completion of construction in 2009, a research program to test the expected physics benefits will start

  4. Workshop presentation: research guidelines for Construction Management

    OpenAIRE

    Marco Alvise Bragadin

    2013-01-01

    Nowadays the European economic system challenges the construction sector to take part to industrial recovery of western countries. In co-operation with the Construction Production research group of the Tampere University of of research about construction management tools and methods were detected. Research guidelines: 1) Construction management: tools and methods to manage construction projects 2) environmental impact of construction projects 3) construction management and safety 4) project p...

  5. Design Solutions for Sustainable Construction of Pre Engineered Steel Buildings

    Directory of Open Access Journals (Sweden)

    Muhammad Umair Saleem

    2018-05-01

    Full Text Available Sustainable construction of ecofriendly infrastructure has been the priority of worldwide researchers. The induction of modern technology in the steel manufacturing industry has enabled designers to get the desired control over the steel section shapes and profiles resulting in efficient use of construction material and manufacturing energy required to produce these materials. The current research study is focused on the optimization of steel building costs with the use of pre-engineered building construction technology. Construction of conventional steel buildings (CSB incorporates the use of hot rolled sections, which have uniform cross-section throughout the length. However, pre-engineered steel buildings (PEB utilize steel sections, which are tailored and profiled based on the required loading effects. In this research study, the performance of PEB steel frames in terms of optimum use of steel sections and its comparison with the conventional steel building is presented in detail. A series of PEB and CSB steel frames is selected and subjected to various loading conditions. Frames were analyzed using Finite Element Based analysis tool and design was performed using American Institute of Steel Construction design specifications. Comparison of the frames has been established in terms of frame weights, lateral displacements (sway and vertical displacements (deflection of the frames. The results have clearly indicated that PEB steel frames are not only the most economical solution due to lesser weight of construction but also have shown better performance compared to CSB frames.

  6. Space construction engineering - A new career field

    Science.gov (United States)

    Hagler, T.

    1979-01-01

    Opportunities for engineers in the design and construction of future large space structures are outlined. Possible space structures for the 1980's include a large mirror to reflect sunlight to earth for night lighting, an antenna for a personal communications system, a deep space communications relay system and a large passive radiometer to measure soil moisture. Considerations in the design of such structures include the lack of gravity, allowing structures to be built with much less supporting weight, the cost of transportation to orbit, leading to the use of aluminum or composite materials stored on reels and attached to a beam builder, and the required surface accuracy in the presence of thermal stresses. Construction factors to consider include the use of astronauts and remote manipulators in assembly, both of which have been demonstrated to be feasible.

  7. Fabrication of myogenic engineered tissue constructs.

    Science.gov (United States)

    Pacak, Christina A; Cowan, Douglas B

    2009-05-01

    Despite the fact that electronic pacemakers are life-saving medical devices, their long-term performance in pediatric patients can be problematic owing to the restrictions imposed by a child's small size and their inevitable growth. Consequently, there is a genuine need for innovative therapies designed specifically for pediatric patients with cardiac rhythm disorders. We propose that a conductive biological alternative consisting of a collagen-based matrix containing autologously-derived cells could better adapt to growth, reduce the need for recurrent surgeries, and greatly improve the quality of life for these patients. In the present study, we describe a procedure for incorporating primary skeletal myoblast cell cultures within a hydrogel matrix to fashion a surgically-implantable tissue construct that will serve as an electrical conduit between the upper and lower chambers of the heart. Ultimately, we anticipate using this type of engineered tissue to restore atrioventricular electrical conduction in children with complete heart block. In view of that, we isolate myoblasts from the skeletal muscles of neonatal Lewis rats and plate them onto laminin-coated tissue culture dishes using a modified version of established protocols. After one to two days, cultured cells are collected and mixed with antibiotics, type 1 collagen, Matrigel, and NaHCO(3). The result is a viscous, uniform solution that can be cast into a mold of nearly any shape and size. For our tissue constructs, we employ type 1 collagen isolated from fetal lamb skin using standard procedures. Once the tissue has solidified at 37 degrees C, culture media is carefully added to the plate until the construct is submerged. The engineered tissue is then allowed to further condense through dehydration for 2 more days, at which point it is ready for in vitro assessment or surgical-implantation.

  8. Rotary engine research

    Science.gov (United States)

    1992-06-01

    A development history is presented for NASA's 1983-1991 Rotary Engine Enablement Program, emphasizing the CFD approaches to various problems that were instituted from 1987 to the end of the program. In phase I, a test rig was built to intensively clarify and characterize the stratified-charge rotary engine concept. In phase II, a high pressure, electronically controlled fuel injection system was tested. In phase III, the testing of improved fuel injectors led to the achievement of the stipulated 5 hp/cu inch specific power goal. CFD-aided design of advanced rotor-pocket shapes led to additional performance improvements.

  9. Involving construction in the preliminary engineering process

    International Nuclear Information System (INIS)

    Mahoney, D.T. Jr.; Boccieri, S.V. Jr.

    1994-01-01

    With today's high cost associated with modifications in nuclear power plants, it is imperative that the authors continue to investigate ways to cut costs but at the same time improve efficiency and reduce radiation exposure to those directly associated with the implementation of modifications. The success associated with involving construction in the preliminary engineering process will not only cut costs and improve efficiency but will establish a Team Building concept to provide accountability to all those associated with the implementation of the task. This form of partnering focuses on the solutions rather than highlighting the difficulties. This paper will demonstrate techniques to implement such ideas and provide examples to corroborate actual successes already achieved

  10. Trend-Analysis and Research Direction in Construction Management Literature

    DEFF Research Database (Denmark)

    Larsen, Jesper Kranker; Ussing, Lene Faber; Brunø, Thomas Ditlev

    2013-01-01

    Planning and scheduling, both in the form of pre-assembly construction as well as increase in cost and time are all themes that haven’t been studies in a trend-analysis, with the purpose of finding gaps and research directions in the literature. The aim of this paper is therefor to analyze...... of Construction Engineering and Management....

  11. Experimental Research of Engine Foundations

    Directory of Open Access Journals (Sweden)

    Violeta-Elena Chiţan

    2004-01-01

    Full Text Available This paper tries a compact presentation of experimental research of engine-foundations. The dynamic phenomena are so complex, that the vibrations cannot be estimated in the design stage. The design engineer of an engine foundation must foresee through a dynamic analysis of the vibrations, those measures that lead to the avoidance or limiting of the bad effects caused by the vibrations.

  12. Research on construction quality and improvement of assembly construction

    Science.gov (United States)

    Cheng, Fei

    2017-11-01

    Based on the acceleration of the urbanization process and the improvement of the quality of life of our residents, the demand for building construction has been increasing. In this context, the construction industry in order to promote the construction efficiency, quality improvement, to meet the needs of the development of the times to strengthen the new technology, the use of new technologies. At present, China’s engineering construction units in the process of carrying out the project to strengthen the use of assembly-type construction technology, which thus achieved for the traditional construction work low-level, high time-consuming issues, and promote the steady improvement of production efficiency. Based on this, this paper focuses on the analysis of the connotation of the assembly structure and analyzes the quality problems in the construction process of the construction projects and puts forward the improvement measures to promote the improvement of the building quality and the construction of the building Construction speed. Based on this, this paper analyzes the structural system and design of prefabricated building.

  13. Research advances in industrial engineering

    CERN Document Server

    2015-01-01

    This book provides discussions and the exchange of information on principles, strategies, models, techniques, methodologies and applications of industrial engineering. It communicates the latest developments and research activity on industrial engineering and is useful for all those interested in the technological challenges in the field.

  14. Engineering Multiphysics Research

    Directory of Open Access Journals (Sweden)

    Tom Eppes

    2011-05-01

    Full Text Available This paper describes an engineering undergraduate course that covers the methods and techniques of multiphysics modeling. Students become active participants in analysis and discovery by being challenged to solve a sequence of problems related to high priority technology areas. Projects range from power systems and thermal control of habitats to autonomous flight systems and harsh environment electronics. Working in a cooperative learning environment, teams encounter a series of assignments that build on existing skills while gradually expanding their knowledge and expertise in disciplines outside of their own. This project-based approach employs a scaffolding structure with assignments organized in progressively challenging modules supported by mentoring. Each project begins with a problem definition which requires consideration of factors and influences beyond a single discipline. Solution development then moves to setting material properties, boundary constraints and including the necessary physics engines. For many students, this is the first in depth exposure to problems with specialized terminologies, driving equations and limiting conditions. Lastly, solving and post processing are addressed exploring steady state, time-variant, frequency response, optimization and sensitivity methods. The paper discusses the teaching and learning strategies, course structure, outcome assessment and project examples.

  15. Detonation Jet Engine. Part 2--Construction Features

    Science.gov (United States)

    Bulat, Pavel V.; Volkov, Konstantin N.

    2016-01-01

    We present the most relevant works on jet engine design that utilize thermodynamic cycle of detonative combustion. Detonation engines of various concepts, pulse detonation, rotational and engine with stationary detonation wave, are reviewed. Main trends in detonation engine development are discussed. The most important works that carried out…

  16. Tissue Engineering Research

    Science.gov (United States)

    2002-01-01

    1996. J. Clinical Investigation 98:2436. Bestor, T. 2000. J. Clinical Invest. 105:409-411. Boden, S., T. Zdeblick, H. Sandhu, and S. Heim. 2000. Spine ...several areas of biomolecules research. Researchers in this group are studying the role of several proteins, including hedgehog and insulin, on the...or spine surgery or dental/craniofacial surgery. Dramatic osteoinduction resulted in acceleration of callus formation and maturation and decrease in

  17. Tissue engineered constructs: perspectives on clinical translation.

    Science.gov (United States)

    Lu, Lichun; Arbit, Harvey M; Herrick, James L; Segovis, Suzanne Glass; Maran, Avudaiappan; Yaszemski, Michael J

    2015-03-01

    In this article, a "bedside to bench and back" approach for developing tissue engineered medical products (TEMPs) for clinical applications is reviewed. The driving force behind this approach is unmet clinical needs. Preclinical research, both in vitro and in vivo using small and large animal models, will help find solutions to key research questions. In clinical research, ethical issues regarding the use of cells and tissues, their sources, donor consent, as well as clinical trials are important considerations. Regulatory issues, at both institutional and government levels, must be addressed prior to the translation of TEMPs to clinical practice. TEMPs are regulated as drugs, biologics, devices, or combination products by the U.S. Food and Drug Administration (FDA). Depending on the mode of regulation, applications for TEMP introduction must be filed with the FDA to demonstrate safety and effectiveness in premarket clinical studies, followed by 510(k) premarket clearance or premarket approval (for medical devices), biologics license application approval (for biologics), or new drug application approval (for drugs). A case study on nerve cuffs is presented to illustrate the regulatory process. Finally, perspectives on commercialization such as finding a company partner and funding issues, as well as physician culture change, are presented.

  18. Research | College of Engineering & Applied Science

    Science.gov (United States)

    Engineering & Applied Science. Please explore this webpage to learn about research activities and Associate Dean for Research College of Engineering and Applied Sciences Director, Center for Sustainable magazine. College ofEngineering & Applied Science Academics About People Students Research Business

  19. Chemical engineering research

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Results of research are reported on hydrodynamics and mass transfer in three-phase fluidized beds. In hydrogen permeation-oxidation studies it was found that at 300 to 500 0 C, and 10-6 oxygen pressure, stainless steel oxidizes 40 to 50 percent of the permeating deuterium. Methods of preparing less than 10-μ sorbent particles were studied using erbium oxide. Adiabatic graphite oxidation studies demonstrated that burning rates are mass transfer controlled, and that the product gas temperature can be controlled by adjusting the recycle gas rate. Apparatus was assembled for evaluation of a perfusion-impactor to remove solid or liquid particles from gas streams. In studies of continuous chromatography the separation of Blue Dextran and CoCl 2 on Spandex G-10 resin was demonstrated

  20. NASA's engineering research centers and interdisciplinary education

    Science.gov (United States)

    Johnston, Gordon I.

    1990-01-01

    A new program of interactive education between NASA and the academic community aims to improve research and education, provide long-term, stable funding, and support cross-disciplinary and multi-disciplinary research. The mission of NASA's Office of Aeronautics, Exploration and Technology (OAET) is discussed and it is pointed out that the OAET conducts about 10 percent of its total R&D program at U.S. universities. Other NASA university-based programs are listed including the Office of Commercial Programs Centers for the Commercial Development of Space (CCDS) and the National Space Grant program. The importance of university space engineering centers and the selection of the nine current centers are discussed. A detailed composite description is provided of the University Space Engineering Research Centers. Other specialized centers are described such as the Center for Space Construction, the Mars Mission Research Center, and the Center for Intelligent Robotic Systems for Space Exploration. Approaches to educational outreach are discussed.

  1. Pedagogical Training and Research in Engineering Education

    Science.gov (United States)

    Wankat, Phillip C.

    2008-01-01

    Ferment in engineering has focused increased attention on undergraduate engineering education, and has clarified the need for rigorous research in engineering education. This need has spawned the new research field of Engineering Education and greatly increased interest in earning Ph.D. degrees based on rigorous engineering education research.…

  2. Development of multilayer constructs for tissue engineering

    NARCIS (Netherlands)

    Bettahalli, N. M. S.; Groen, N.; Steg, H.; Unadkat, H.; de Boer, J.; van Blitterswijk, C. A.; Wessling, M.; Stamatialis, D.

    The rapidly developing field of tissue engineering produces living substitutes that restore, maintain or improve the function of tissues or organs. In contrast to standard therapies, the engineered products become integrated within the patient, affording a potentially permanent and specific cure of

  3. Development of multilayer constructs for tissue engineering

    NARCIS (Netherlands)

    Bettahalli Narasimha, M.S.; Groen, N.; Steg, H.; Unadkat, H.V.; de Boer, Jan; van Blitterswijk, Clemens; Wessling, Matthias; Stamatialis, Dimitrios

    2014-01-01

    The rapidly developing field of tissue engineering produces living substitutes that restore, maintain or improve the function of tissues or organs. In contrast to standard therapies, the engineered products become integrated within the patient, affording a potentially permanent and specific cure of

  4. Qualitative Knowledge Construction for Engineering Systems: Extending the Design Structure Matrix Methodology in Scope and Procedure

    National Research Council Canada - National Science Library

    Bartolomei, Jason E

    2007-01-01

    ...), by providing a dynamic, end-to-end representation of an engineering system. In support of this contribution, a new research methodology is presented called Qualitative Knowledge Construction (QKC...

  5. Engineering research, development and technology

    International Nuclear Information System (INIS)

    1994-05-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the technical staff, tools, and facilities needed to support current and future LLNL programs. The efforts are guided by a dual-benefit research and development strategy that supports Department of Energy missions, such as national security through nuclear deterrence and economic competitiveness through partnerships with U.S. industry. This annual report, organized by thrust area, describes the activities for the fiscal year 1993. The report provides timely summaries of objectives, methods, and results from nine thrust areas for this fiscal year: Computational Electronics and Electromagnetics; Computational Mechanics; Diagnostics and Microelectronics; Fabrication Technology; Materials Science and Engineering; Power Conversion Technologies; Nondestructive Evaluation; Remote Sensing, Imaging, and Signal Engineering; and Emerging Technologies. Separate abstracts were prepared for 47 papers in this report

  6. Digital fabrication in architecture, engineering and construction

    CERN Document Server

    Caneparo, Luca

    2014-01-01

    Digital technologies are changing the relationship between design and construction: with computer models, CAD/CAM, and prototyping, designers can gain direct control of building and construction processes. The ability to digitally model designs, and thus to use those models directly in the context of production, creates a synthesis between design and construction in keeping with the tradition of the close relationship between design and craftsmanship, between the quality of the design and the rules of the craft. The evolution of the culture of design and construction is the underlying theme of this book. The aim is to discuss the direction that innovation is now taking, with a particular focus on today’s cutting-edge architectures. The method addresses the ways in which different societies have dealt with the issues of their age regarding design and construction, the different contributions provided by various techniques, and with them the meanings expressed by the architecture. As building design using dig...

  7. Final Environmental Assessment of Construction of Emerald Coast Technology and Research Campus at the University of Florida Reserarch Engineering Education Facility at Eglin Air Force Base, Florida

    Science.gov (United States)

    2012-03-01

    document should be directed to Mr. Larry Chavers. Public comments should be directed to Mr. Mike Spaits. Mr. Chavers and Mr. Spaits can be reached...Section. • Should a gopher tortoise burrow be identified within the proposed path of construction by construction personnel, work will cease until...Natural Resources personnel have investigated the burrow and relocated any gopher tortoise or commensals to a suitable location. 3 • Gopher tortoise and

  8. Methodology discourses as boundary work in the construction of engineering education.

    Science.gov (United States)

    Beddoes, Kacey

    2014-04-01

    Engineering education research is a new field that emerged in the social sciences over the past 10 years. This analysis of engineering education research demonstrates that methodology discourses have played a central role in the construction and development of the field of engineering education, and that they have done so primarily through boundary work. This article thus contributes to science and technology studies literature by examining the role of methodology discourses in an emerging social science field. I begin with an overview of engineering education research before situating the case within relevant bodies of literature on methodology discourses and boundary work. I then identify two methodology discourses--rigor and methodological diversity--and discuss how they contribute to the construction and development of engineering education research. The article concludes with a discussion of how the findings relate to prior research on methodology discourses and boundary work and implications for future research.

  9. Heat stress intervention research in construction: gaps and recommendations.

    Science.gov (United States)

    Yang, Yang; Chan, Albert Ping-Chuen

    2017-06-08

    Developing heat stress interventions for construction workers has received mounting concerns in recent years. However, limited efforts have been exerted to elaborate the rationale, methodology, and practicality of heat stress intervention in the construction industry. This study aims to review previous heat stress intervention research in construction, to identify the major research gaps in methodological issues, and to offer detailed recommendations for future studies. A total of 35 peer-reviewed journal papers have been identified to develop administrative, environmental or personal engineering interventions to safeguard construction workers. It was found that methodological limitations, such as arbitrary sampling methods and unreliable instruments, could be the major obstacle in undertaking heat stress intervention research. To bridge the identified research gaps, this study then refined a research framework for conducting heat stress intervention studies in the construction industry. The proposed research strategy provides researchers and practitioners with fresh insights into expanding multidisciplinary research areas and solving practical problems in the management of heat stress. The proposed research framework may foster the development of heat stress intervention research in construction, which further aids researchers, practitioners, and policymakers in formulating proper intervention strategies.

  10. Bi-project management in engineering complex industrial construction projects

    NARCIS (Netherlands)

    Velde, Robert R. van der; Donk, Dirk Pieter van

    2000-01-01

    Engineering large industrial construction projects is usually a complex task with several co-operating actors. This paper investigates such projects, characterised by two main actors: the owner of the installation (the client organisation) responsible for the engineering of the production process,

  11. FY2012 Engineering Research & Technology Report

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Monya

    2014-07-22

    This report documents engineering research, development, and technology advancements performed by LLNL during fiscal year 2012 in the following areas: computational engineering, engineering information systems, micro/nano-devices and structures, and measurement technologies.

  12. Identifying Indicators Related to Constructs for Engineering Design Outcome

    Science.gov (United States)

    Wilhelmsen, Cheryl A.; Dixon, Raymond A.

    2016-01-01

    This study ranked constructs articulated by Childress and Rhodes (2008) and identified the key indicators for each construct as a starting point to explore what should be included on an instrument to measure the engineering design process and outcomes of students in high schools that use the PLTW and EbDTM curricula in Idaho. A case-study design…

  13. Construction Site Environmental Impact in Civil Engineering Education

    Science.gov (United States)

    Teixeira, Jose M. Cardoso

    2005-01-01

    The environmental impact of construction activity has gained increasing importance in the last few years and become a key subject for civil engineering education. A survey of Portuguese higher education institutions shows that concern with this topic is mostly directed at the impact of large construction projects and especially focused on their…

  14. Proceedings of the national seminar on advanced construction techniques and geotechnical engineering

    International Nuclear Information System (INIS)

    Partheeban, P.; Poornima, C.A.; Guru, V.

    2015-02-01

    The objective of this seminar is to emphasize the need for developing modern construction materials in the era of technology. It also provides a forum for National Research Scholars, Construction Specialists and Professionals, Planners, Faculty, PG and UG Students to discuss and evolve solutions for various difficulties faced during construction. Theme of seminar includes Geotechnical site Investigation, Ground improvement Techniques, Soil Dynamics, Geotechnical Earthquake Engineering, Geo- Environmental Engineering, Self Compacting Concrete, Geopolymer Concrete and Concrete Technology, Cost Effective Construction Techniques, Limit state performance state approach Elastic and Elasto-plastic behavior and Reduction of Corrosion in concrete using Chemical admixtures. Paper relevant to INIS are indexed separately

  15. Seeking Constructive Synergy: Design Science and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2013-01-01

    Information systems research and management science create knowledge which can be applied in organizations. Design science specifically aims at applying existing knowledge to solve interesting and relevant business problems and has been steadily gaining support in information systems research....... However, design science is not the only design-oriented framework. Accordingly, this raises the question of whether it is possible to compare the results obtained from different brands of design-oriented research. This paper contributes to answering this question by comparing two research approaches......, enabling mutual learning possibilities and suggesting improvements in transparency and rigor. The objective of this paper is to compare design science research with the constructive research approach. The conclusion is that the two approaches are compatible, save for details in practical requirements...

  16. Study on evaluation of construction reliability for engineering project based on fuzzy language operator

    Science.gov (United States)

    Shi, Yu-Fang; Ma, Yi-Yi; Song, Ping-Ping

    2018-03-01

    System Reliability Theory is a research hotspot of management science and system engineering in recent years, and construction reliability is useful for quantitative evaluation of project management level. According to reliability theory and target system of engineering project management, the defination of construction reliability appears. Based on fuzzy mathematics theory and language operator, value space of construction reliability is divided into seven fuzzy subsets and correspondingly, seven membership function and fuzzy evaluation intervals are got with the operation of language operator, which provides the basis of corresponding method and parameter for the evaluation of construction reliability. This method is proved to be scientific and reasonable for construction condition and an useful attempt for theory and method research of engineering project system reliability.

  17. Construction dispute research conceptualisation, avoidance and resolution

    CERN Document Server

    2014-01-01

    There are three specific purposes of Construction Dispute Research. First, this volume aims to summarise studies on construction dispute. Second, apart from the theoretical constructs, where appropriate empirical tests are also included. This approach serves to go beyond the commonly used anecdotal approach for the subject matters. Third, it is the sincere hope of the authors that this book will help shaping research agenda of construction dispute.  The studies are mostly framed from a management perspective drawing on methods and concepts in contract law, economics, psychology and management science.   The book has twenty chapters that are arranged in four parts covering conceptualisation, avoidance, negotiation and mediation. Part 1 is devoted for dispute conceptualisation. A building is only as strong as its foundation. Thus it is no better start to study construction dispute by conceptualisation. The theme of Part 2 is dispute avoidance. The conventional wisdom of ‘prevention is better than cure’ se...

  18. Sizewell 'B' power station - engineering and construction

    International Nuclear Information System (INIS)

    Walker, A.

    1989-01-01

    The Sizewell 'B' design is based on the Callaway PWR station in Missouri, USA. There have been many papers describing the additional criteria covering safety, operational experience and design and manufacturing practices which were applied to the Callaway reference design and which led to the Sizewell 'B' design concept. This paper describes the implementation of some of these design criteria leading to the layout related design features. Comparisons are drawn with the reference design. This paper concludes by describing various aspects of the design and construction process and the progress which has been made on the Sizewell site. (author)

  19. An Investigation of Women Engineers in Non-Traditional Occupations in the Thai Construction Industry

    Directory of Open Access Journals (Sweden)

    Nuanthip Kaewsri

    2011-06-01

    Full Text Available For over a decade, the public and the private sectors have carried out research aimed at attracting women engineers to the construction industry and retaining them. However, studies on women engineers working in other types of construction-related businesses apart from contractor companies such as consultancies, developers, etc., have not been many. This paper aims to examine the experiences of women engineers in non-traditional careers and the implications for their turnover. A literature search on women’s careers in construction was performed in conjunction with semi-structured interviews with a sampling of 141 individuals. Results from three viewpoints, viz those of professional men and women engineers in contractor companies, and women engineers in non-contractor companies, were found to differ in many respects, including their opinions about career advancement, career path and the difficulties involved. It was also found that women engineers in contractor companies were much more affected by problems such as sexual harassment, work-life conflicts and equal opportunity than women engineers in non-contractor companies. Turnover rates of women engineers and their reasons for leaving were examined. Women engineers, particularly those in contractor companies, had to confront more barriers in non-traditional careers than their male counterparts.  Nonetheless, working in non-contractor companies provides a viable alternative for women engineers who want to have successful careers in the Thai construction industry.

  20. Engineering of rolled constructional microalloyed steel products

    International Nuclear Information System (INIS)

    Adamczyk, J.

    2003-01-01

    Flexibility of the microalloyed steels on manufacturing of products with high mechanical and technological properties at not exaggerated production costs, it caused of their application for different constructions and machines in many branches of economy. It is a reason of the big interest of this steel group and the improvement of metallurgical and technological processing. In the work the examples of applications of C-Mn microalloyed steels with V and N microadditions for production of long shape products of R p0.2 > 650 MPa and KCU2 > 57 Jcm -2 are presented. They are manufactured in the controlled rolling process. Moreover this work presents liquid metal treatment in ladlemann process and influence of ingots solidification conditions, controlled rolling of weldable plates with Nb, Ti, V and B microadditions which after quenching and tempering have R p0.2 > 870 MPa, KV -50 o C > 27 J and plastic strain ratio equals 1.2. This work also presents the energy saving rolling technology with controlled recrystallization (method of thermomechanical treatment) of improved Weldox 960 steel plates with Mb, Ti, V and B microadditions which have after high-temperature tempering R p0.2 > 100 MPa, KV -50 o C >90 J and plastic strain ratio is less than 1.2. The introduction of microalloyed constructional steels and the appropriate technology in the domestic industry will contribute to high-processed products with properties competitive to products manufactured in high-industrialized countries. Thanks to that it will be possible to increase the technical level as well as to reduce production costs and import. (author)

  1. Design and construction of multi research reactor

    International Nuclear Information System (INIS)

    1985-05-01

    This is the report about design and construction of multi research reactor, which introduces the purpose and necessity of the project, business contents, plan of progress of project and budget for the project. There are three appendixes about status of research reactor in other country, a characteristic of research reactor, three charts about evaluation, process and budget for the multi research reactor and three drawings for the project.

  2. A framework for systems engineering research

    CSIR Research Space (South Africa)

    Erasmus, L

    2013-08-01

    Full Text Available This presentation discusses a framework which is proposed to perform systems engineering research within South Africa and the necessity for hybrid research methods in systems engineering....

  3. Journal of Civil Engineering Research and Practice

    African Journals Online (AJOL)

    The Journal of Civil Engineering Research and Practice aims to publish original research papers of high standard, containing material of significant contribution to civil engineering, with emphasis being placed on material that is applicable to the solution of practical problems.

  4. Advanced plant engineering and construction of Japanese ABWRs

    International Nuclear Information System (INIS)

    Gotoh, N.; Sumikawa, J.; Yoshida, N.; Yoshida, M.

    1998-01-01

    Remarkable improvement has been made in recent nuclear power plant design and construction in Japan. These many improved engineering technologies has been made a good use in the lately commercial operated two world's first 1,356MWe ABW's (Advanced Boiling Water Reactors), and made a great contribution to the smooth progress and the completion of a highly reliable plant construction. Especially, two engineering technologies, (1), three-dimensional computer aided design system through engineering data-base, and (2), large scale modularising construction method, have been successfully applied as the integrated engineering technologies of the plant construction. And two integrated reviews, 'integrated design review, confirmation of new and changed design and prevention of failure recurrence' in the design stage, and 'constructing plant review' at the site, have been widely and systematically conducted as a link in the chain of steady reliability improvement activities. These advanced and/or continuous and steady technologies are one of most important factors for high reliability through the entire lifetime of a nuclear plant, including planning, design, construction, operation and maintenance stages. (author)

  5. Improving Construction Process through Integration and Concurrent Engineering

    Directory of Open Access Journals (Sweden)

    Malik Khalfan

    2012-11-01

    Full Text Available In an increasingly competitive business environment, improvedtime-to-market, reduced production cost, quality of the productand customer involvement are rapidly becoming the key successfactors for any product development process. Consequently, mostorganisations are moving towards the adoption of latest technologyand new management concepts and philosophies such as totalquality management and concurrent engineering (CE to bringimprovement in their product development process. This paperdiscusses the adoption of integrated processes and CE withinthe construction industry to enable construction organisations toimprove their project development process. It also discusses aproposed integrated database model for the construction projects,which should enable the construction process to improve, becomemore effective and more efficient.

  6. A Resilience Engineering Approach for Sustainable Safety in Green Construction

    Directory of Open Access Journals (Sweden)

    Lucio V. Rosa

    2017-12-01

    Full Text Available Sustainable construction is a complex endeavour, involving various stakeholders and resulting in situations that are incompletely described or underspecified. Traditional risk assessment methods require a detailed description of the system and safety, focusing on undesirable outcomes, losses, incidents and accidents. Developing this principle, this research describes a new way to deal with risk assessment in the green construction industry using a resilience engineering method based on the functional resonanceanalysis method and analytic hierarchy process methodologies. The functional resonance analysis method defines a systemic framework to model complex systems based on combinations of function variabilities during normal work. Therefore, to quantify the outcomes for risk assessment, this method was used together with the analytic hierarchy process in a case study during the modernisation work on the Maracanã stadium in Rio de Janeiro. The results of this case study demonstrate that the combined utilisation of the functional resonance analysis method and analytic hierarchy process can be utilised to recognise situations where developments could potentially be without control, which enables this to be used as a basis for performing indicators or a monitoring system. Furthermore, this combined technique can be used to assess and quantify the performance variabilities that may lead to occupational or environmental accidents, and provide new recommendations about how work processes should function, minimising production losses, incidents and accidents.

  7. Small-Engine Research Laboratory (SERL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Small-Engine Research Laboratory (SERL) is a facility designed to conduct experimental small-scale propulsion and power generation systems research....

  8. Materials for construction and civil engineering science, processing, and design

    CERN Document Server

    Margarido, Fernanda

    2015-01-01

    This expansive volume presents the essential topics related to construction materials composition and their practical application in structures and civil installations. The book's diverse slate of expert authors assemble invaluable case examples and performance data on the most important groups of materials used in construction, highlighting aspects such as nomenclature, the properties, the manufacturing processes, the selection criteria, the products/applications, the life cycle and recyclability, and the normalization. Civil Engineering Materials: Science, Processing, and Design is ideal for practicing architects; civil, construction, and structural engineers, and serves as a comprehensive reference for students of these disciplines. This book also: ·       Provides a substantial and detailed overview of traditional materials used in structures and civil infrastructure ·       Discusses properties of natural and synthetic materials in construction and materials' manufacturing processes ·  �...

  9. Value engineering awareness study for sustainable construction in Malaysia

    International Nuclear Information System (INIS)

    Fathoni U; Zakaria C M; Rohayu C O

    2013-01-01

    Construction process has often been described as a highly complex process because of the number of disciplines involved during the conceptual, design and construction stage. With the emergence of latest technology and concern for environment, increasing attention in construction industry is given on sustainability. Balance in quality and sustainability has become a major challenge to the construction industry. This paper presents a study that has conducted to determine the acceptance and application of Value Engineering (VE) and Life Cycle Cost Analysis (LCCA) in Malaysia construction industry. A set of questionnaire have distributed to different practitioners in construction industry and the result has reflect the fact that the application of VE and LCCA are still very low.

  10. Organizing the engineering basis of works during NPP construction

    International Nuclear Information System (INIS)

    Gorodinskij, Yu.Kh.; Finberg, L.K.; Shapiro, V.I.

    1988-01-01

    Experience in organization of the system of engineering basis of works during the Khmelnitskij NPP construction, aimed at providing the applicability of the software complex realized with a computer when solving the problems arising before the service of engineering basis of works, is described. Calculational complex for solving the problems on the engineering basis of works includes the SM-2420 processor, immediate access and external storages on MD with capacity not less than 1 and 60 Mbit correspondignly, terminal multiplexer, VTA 2000-15 video terminals, not less than 10 pieces of videotons and not less than two SM-6315 alphanumerical printers

  11. Artificial urinary conduit construction using tissue engineering methods.

    Science.gov (United States)

    Kloskowski, Tomasz; Pokrywczyńska, Marta; Drewa, Tomasz

    2015-01-01

    Incontinent urinary diversion using an ileal conduit is the most popular method used by urologists after bladder cystectomy resulting from muscle invasive bladder cancer. The use of gastrointestinal tissue is related to a series of complications with the necessity of surgical procedure extension which increases the time of surgery. Regenerative medicine together with tissue engineering techniques gives hope for artificial urinary conduit construction de novo without affecting the ileum. In this review we analyzed history of urinary diversion together with current attempts in urinary conduit construction using tissue engineering methods. Based on literature and our own experience we presented future perspectives related to the artificial urinary conduit construction. A small number of papers in the field of tissue engineered urinary conduit construction indicates that this topic requires more attention. Three main factors can be distinguished to resolve this topic: proper scaffold construction along with proper regeneration of both the urothelium and smooth muscle layers. Artificial urinary conduit has a great chance to become the first commercially available product in urology constructed by regenerative medicine methods.

  12. Interfacing between concrete and steel construction and fusion research devices

    International Nuclear Information System (INIS)

    Willoughby, E.

    1981-01-01

    In 1976 Giffels Associates, Inc. an architect/engineer organization, was retained by the United States Department of Energy to provide Title I and Title II design services and Title III construction inspection services for the Tokamak Fusion Test Reactor now being installed at the Princeton Plasma Physics Laboratory in Princeton, New Jersey. Construction of the complex required to house and serve the reactor itself, designed by others, now commencing. During building construction several problems occurred with respect to the interface between the building design, construction and the fusion device (reactor). A brief description of some of these problems and related factors is presented, which may be of benefit to those persons active in continuing fusion research and experimental work

  13. Feminist Methodologies and Engineering Education Research

    Science.gov (United States)

    Beddoes, Kacey

    2013-01-01

    This paper introduces feminist methodologies in the context of engineering education research. It builds upon other recent methodology articles in engineering education journals and presents feminist research methodologies as a concrete engineering education setting in which to explore the connections between epistemology, methodology and theory.…

  14. Biopolitics problems of large-scale hydraulic engineering construction

    International Nuclear Information System (INIS)

    Romanenko, V.D.

    1997-01-01

    The XX century which will enter in a history as a century of large-scale hydraulic engineering constructions come to the finish. Only on the European continent 517 large reservoirs (more than 1000 million km 3 of water were detained, had been constructed for a period from 1901 till 1985. In the Danube basin a plenty for reservoirs of power stations, navigations, navigating sluices and other hydraulic engineering structures are constructed. Among them more than 40 especially large objects are located along the main bed of the river. A number of hydro-complexes such as Dnieper-Danube and Gabcikovo, Danube-Oder-Labe (project), Danube-Tissa, Danube-Adriatic Sea (project), Danube-Aegean Sea, Danube-Black Sea ones, are entered into operation or are in a stage of designing. Hydraulic engineering construction was especially heavily conducted in Ukraine. On its territory some large reservoirs on Dnieper and Yuzhny Bug were constructed, which have heavily changed the hydrological regime of the rivers. Summarised the results of river systems regulating in Ukraine one can be noted that more than 27 thousand ponds (3 km 3 per year), 1098 reservoirs of total volume 55 km 3 , 11 large channels of total length more than 2000 km and with productivity of 1000 m 2 /s have been created in Ukraine. Hydraulic engineering construction played an important role in development of the industry and agriculture, water-supply of the cities and settlements, in environmental effects, and maintenance of safe navigation in Danube, Dnieper and other rivers. In next part of the paper, the environmental changes after construction of the Karakum Channel on the Aral Sea in the Middle Asia are discussed

  15. Contracting Economics of Large Engineering and Construction Projects

    NARCIS (Netherlands)

    Berends, T.C.

    2007-01-01

    Large Engineering and Construction Projects (LECPs) form an important area of economic activity, covering a range of different artefacts. These projects have in common that they are massive undertakings, spanning long time periods and they involve large capital investments. Uncertainty and risk are

  16. Necessity for ethics in social engineering research

    CSIR Research Space (South Africa)

    Mouton, F

    2015-11-01

    Full Text Available Social engineering is deeply entrenched in the fields of both computer science and social psychology. Knowledge is required in both these disciplines to perform social engineering based research. Several ethical concerns and requirements need...

  17. Modern mechanical engineering research, development and education

    CERN Document Server

    2014-01-01

    This book covers modern subjects of mechanical engineering such as nanomechanics and nanotechnology, mechatronics and robotics, computational mechanics, biomechanics, alternative energies, sustainability as well as all aspects related with mechanical engineering education. The chapters help enhance the understanding of both the fundamentals of mechanical engineering and its application to the solution of problems in modern industry. This book is suitable for students, both in final undergraduate mechanical engineering courses or at the graduate level. It also serves as a useful reference for academics, mechanical engineering researchers, mechanical, materials and manufacturing engineers, professionals in related with mechanical engineering.

  18. Complex researches on substantiation of construction and seismic stability of large dams in seismic region

    International Nuclear Information System (INIS)

    Negmatullaev, S.Kh.; Yasunov, P.A.

    2001-01-01

    This article is devoted to complex researches on substantiation of construction and seismic stability of large dams (Nurec hydroelectric power station) in seismic region. Geological, seismological, model, and engineering investigations are discussed in this work. At construction of Nurec hydroelectric power station the rich experience is accumulated. This experience can be used in analogous seismically active regions at construction similar hydroelectric power stations.

  19. Global Journal of Engineering Research: Editorial Policies

    African Journals Online (AJOL)

    Focus and Scope. The Global Journal of Engineering Research is aimed at promoting research in all areas of Engineering Research including Mechanical, Civil, Electrical, Chemical, Electronics, Geological etc. Section Policies. Articles. Checked Open Submissions, Checked Indexed, Checked Peer Reviewed. Publication ...

  20. Sandia National Laboratories: Research: Research Foundations: Engineering

    Science.gov (United States)

    Foundations Bioscience Computing & Information Science Electromagnetics Engineering Science Geoscience Mexico Small Business Assistance Program Sandia Science & Technology Park Careers Community Library Events Careers View All Jobs Students & Postdocs Internships & Co-ops Fellowships

  1. Engineering Research in Irish Economic Development

    Science.gov (United States)

    Kelly, John

    2011-01-01

    This article summarizes the main findings and recommendations of a report published in December 2010 by the Irish Academy of Engineering (IAE). The report, representing the views of a committee of distinguished Irish engineers from a wide range of disciplines, addresses the role of engineering research in Ireland's economic development and the…

  2. Modelling a Global EPCM (Engineering, Procurement and Construction Management Enterprise

    Directory of Open Access Journals (Sweden)

    Sekhar Chattopadhyay

    2010-03-01

    Full Text Available This paper investigates the applicability of enterprise architectures in the context of current business environment by examining the application of Purdue Enterprise Reference Architecture to WorleyParsons, a global engineering, procurement and construction management enterprise, under the backdrop of a similar study carried out on Fluor Daniel during mid-nineties of the last century. The outcome of this study recommends the need for new enterprise architecture, the People-Centric Enterprise Architecture that not only focuses on human dimension in modern enterprises as the central thread, but also includes more business characteristics of the enterprise other than engineerings.

  3. Complex engineering objects construction using Multi-D innovative technology

    International Nuclear Information System (INIS)

    Agafonov, Alexey

    2013-01-01

    Multi-D technology is an integrated innovative project management system for a construction of complex engineering objects based on a construction process simulation using an intellectual 3D model. Multi-D technology includes: • The unified schedule of E+P+C; • The schedule of loading of human resources, machines & mechanisms; • The budget of expenses and the income integrated with the schedule; • 3D model; • Multi-D model; • Weekly-daily tasks (with 4th level schedules); • Control system of interaction of Customer-EPC(m) company - Contractors; • Change and configuration management system

  4. LHC Civil Engineering Construction Contracts Cost Monitoring and Budget Forecasting

    CERN Document Server

    Skelton, K

    2000-01-01

    The Civil Engineering project for the LHC is estimated at 350 MCHF, of which about 316 MCHF is for the construction contracts. These contracts are based on a system of remeasurement whereby the consultant estimates the quantities required for the construction of each structure and the contractor commits himself to the unit price, which define the initial tender price. There are many factors that affect the final price for these contracts, from increases or decreases in quantities of the estimated amounts in the original bill of quantities to variations to the contract. This paper will look at how these factors change costs at the individual level of a structure to the overall costs of the contract. It will look at how the Civil Engineering Group monitors these changes to calculate cash flows and final costs and how this information is used as a basis for budget forecasts.

  5. Facilitating Industrial Placement in the Construction Engineering Curriculum

    DEFF Research Database (Denmark)

    Wandahl, Søren; Ussing, Lene Faber

    2016-01-01

    outset in the hypothesis that external effectiveness (industry readiness) is better in those modes of education that, at least in part, are based on the world of work itself, and several sources highlight the necessity of strong links between engineering education and industry. Hence, it becomes central......There is often a claim that there is a disconnection between theory and practice, which raises questions on student’s readiness for employment and the extent that higher education responds effectively to the evolving needs of the construction industry. Industrial placements schemes can facilitate...... student learning from construction practice whereby students can reflect on their learning experience at the university. The interplay between traditional engineering curriculum and the context-based learning is important for securing the right skills and competencies among the graduates. This paper takes...

  6. Videogame Construction by Engineering Students for Understanding Modelling Processes: The Case of Simulating Water Behaviour

    Science.gov (United States)

    Pretelín-Ricárdez, Angel; Sacristán, Ana Isabel

    2015-01-01

    We present some results of an ongoing research project where university engineering students were asked to construct videogames involving the use of physical systems models. The objective is to help them identify and understand the elements and concepts involved in the modelling process. That is, we use game design as a constructionist approach…

  7. Recent Efforts and Experiments in the Construction of Aviation Engines

    Science.gov (United States)

    SCHWAGER

    1920-01-01

    It became evident during World War I that ever-increasing demands were being placed on the mean power of aircraft engines as a result of the increased on board equipment and the demands of aerial combat. The need was for increased climbing efficiency and climbing speed. The response to these demands has been in terms of lightweight construction and the adaptation of the aircraft engine to the requirements of its use. Discussed here are specific efforts to increase flying efficiency, such as reduction of the number of revolutions of the propeller from 1400 to about 900 r.p.m. through the use of a reduction gear, increasing piston velocity, locating two crankshafts in one gear box, and using the two-cycle stroke. Also discussed are improvements in the transformation of fuel energy into engine power, the raising of compression ratios, the use of super-compression with carburetors constructed for high altitudes, the use of turbo-compressors, rotary engines, and the use of variable pitch propellers.

  8. The Strategy of Management Тraining in the Construction Engineering

    Directory of Open Access Journals (Sweden)

    Khripko Elena

    2017-01-01

    Full Text Available The operating efficiency of leaders in the construction industry is largely determined by the level of formation of managerial skills. Along with this, it is stated that the process of formation and development of managerial skills for leaders in the construction engineering is attended by a number of difficulties and frequently doesn’t make it past the threshold. This paper formulates a new approach in the formation of managerial skills of leaders in the construction engineering. The cross-sectoral assessment of managerial skills featuring the heads of the construction engineering and other industries, such as energy, metallurgy, showed low-performing managerial skills for the heads of the construction industry. The reasons of the formation of low-performing managerial skills in this article are referred to as peculiar features of organizational behavior in the construction engineering, in particular an imminent regression in the leader-follower system. Based on the results of the research conducted, the similarity of issues in regard to managerial skills in these areas is inherent in key differences in the formulation of priorities of corporate competencies.

  9. Research on the User Interest Modeling of Personalized Search Engine

    Institute of Scientific and Technical Information of China (English)

    LI Zhengwei; XIA Shixiong; NIU Qiang; XIA Zhanguo

    2007-01-01

    At present, how to enable Search Engine to construct user personal interest model initially, master user's personalized information timely and provide personalized services accurately have become the hotspot in the research of Search Engine area.Aiming at the problems of user model's construction and combining techniques of manual customization modeling and automatic analytical modeling, a User Interest Model (UIM) is proposed in the paper. On the basis of it, the corresponding establishment and update algorithms of User Interest Profile (UIP) are presented subsequently. Simulation tests proved that the UIM proposed and corresponding algorithms could enhance the retrieval precision effectively and have superior adaptability.

  10. Research Trends with Cross Tabulation Search Engine

    Science.gov (United States)

    Yin, Chengjiu; Hirokawa, Sachio; Yau, Jane Yin-Kim; Hashimoto, Kiyota; Tabata, Yoshiyuki; Nakatoh, Tetsuya

    2013-01-01

    To help researchers in building a knowledge foundation of their research fields which could be a time-consuming process, the authors have developed a Cross Tabulation Search Engine (CTSE). Its purpose is to assist researchers in 1) conducting research surveys, 2) efficiently and effectively retrieving information (such as important researchers,…

  11. Fuel Combustion and Engine Performance | Transportation Research | NREL

    Science.gov (United States)

    Fuel Combustion and Engine Performance Fuel Combustion and Engine Performance Photo of a gasoline emissions in advanced engine technologies. Photo by Dennis Schroeder, NREL NREL's combustion research and combustion and engine research activities include: Developing experimental and simulation research platforms

  12. Virtual Parts Engineering Research Center

    Science.gov (United States)

    2010-05-20

    engineering 10 materials. High strength alloys , composites (polymer composites and metallic composites), and the like cannot merely be replaced by...ceramics, smart materials, shape memory alloys , super plastic materials and nano- structured materials may be more appropriate substitutes in a reverse...molding process using thermosetting Bakelite. For remanufacturing the part in small quantities, machining has been identified as the most economical

  13. A Bibliometric Analysis of Climate Engineering Research

    Science.gov (United States)

    Belter, C. W.; Seidel, D. J.

    2013-12-01

    The past five years have seen a dramatic increase in the number of media and scientific publications on the topic of climate engineering, or geoengineering, and some scientists are increasingly calling for more research on climate engineering as a possible supplement to climate change mitigation and adaptation strategies. In this context, understanding the current state of climate engineering research can help inform policy discussions and guide future research directions. Bibliometric analysis - the quantitative analysis of publications - is particularly applicable to fields with large bodies of literature that are difficult to summarize by traditional review methods. The multidisciplinary nature of the published literature on climate engineering makes it an ideal candidate for bibliometric analysis. Publications on climate engineering are found to be relatively recent (more than half of all articles during 1988-2011 were published since 2008), include a higher than average percentage of non-research articles (30% compared with 8-15% in related scientific disciplines), and be predominately produced by countries located in the Northern Hemisphere and speaking English. The majority of this literature focuses on land-based methods of carbon sequestration, ocean iron fertilization, and solar radiation management and is produced with little collaboration among research groups. This study provides a summary of existing publications on climate engineering, a perspective on the scientific underpinnings of the global dialogue on climate engineering, and a baseline for quantitatively monitoring the development of climate engineering research in the future.

  14. The role of women in construction research

    Directory of Open Access Journals (Sweden)

    Gómez, A.

    2010-02-01

    Full Text Available Equal participation of women and men in industrial research is still a major challenge for the European Union. In most European countries, female graduates proportionately outnumber male graduates. However, scientific research and technological development remain male-dominated, especially in industry. Construction is one of the most important industrial sectors in terms of economic growth and employmet, but very little is known about the role of women in construction research and the factors that are hindering a more equal presence of women and men. As result of an extensive field work undertaken at European level, this paper offers a picture of the current situation of women in construction research that shows evidences of important inequalities. This work has allowed the development of recommendations for empowering women in construction research, addressing the opportunities for moving towards gender equality in this field. To invest in human capital for research is seen as an outstanding necessity within construction sector, and both women and men should fully develop their potential.

    La participación equitativa de mujeres y hombres en la investigación científica y el desarrollo tecnológico (I+D es todavía un desafío por alcanzar en la Unión Europea. Las mujeres europeas siguen estando infra-representadas en este espacio, especialmente en los sectores industriales, a pesar de que en la mayoría de los países miembros la proporción de graduadas excede a la de graduados varones. Esta comunicación presenta cómo es la situación de las investigadoras en el sector de la construcción en Europa, centrando la atención en el papel que juegan en la I+D de este sector, su influencia, perspectivas de futuro, retos y oportunidades. Se presentan los principales resultados soportados por un extensivo trabajo de campo cofinanciado por la Comisión Europea, que muestran una situación de importante desigualdad. Este trabajo ha originado

  15. Research methods of the parameters of residential buildings construction

    Directory of Open Access Journals (Sweden)

    Grigor’ev Vladimir Aleksandrovich

    Full Text Available The analysis of construction theory and practice shows that rational organizational and technological parameters of the construction of residential buildings should be based on the manifestation in time and space of the most important stages construction with their harmonization. Basing on the experience of normalizing the construction duration, it is advisable to express the complex of residential buildings’ construction processes by their basic stages - preparatory period, underground part, aboveground part, external engineering networks and land improvement. The main indicators of the development and implementation of optimization solutions are: the total duration of the construction, the duration of the preparation period, the duration of the construction of the underground part, the duration of the construction of the aboveground part, the duration of external engineering networks laying, the duration of land improvement. The indicators of the total duration of the construction of residential buildings, the construction the underground and aboveground parts are determined on the basis of the operation of one assembly crane on an object of up to four sections. In case of more sections two (three cranes are considered and the total construction duration is set depending on these conditions. The duration of the construction of multisectional buildings is determined basing on the simultaneous construction of the stages or their combination with a certain time shift. However, this approach requires a significant amount of optimization solutions due to its multivariance. Therefore, in order to reduce the volume of calculations in some cases, for example, when planning the development of districts and neighborhoods, statistical methods can be used for determining the duration of the construction basing on the compilation of optimization solutions. The total duration of the construction and the duration of the main stages are multiple

  16. Construction project of Flamanville 3 NPP. The participation of Iberdrola engineering and Construction

    International Nuclear Information System (INIS)

    Diaz Prada, J. I.; Cubian, B.

    2014-01-01

    Iberdrola Engineering and Construction (IIC) leads several projects mini EPC for the EPR Flamanville 3 NPP for providing important for safety components and auxiliary systems in the pump house and in the turbine island. The realization of this new nuclear project has been a challenge from the technical and organizational perspective because the plant is the first of the new nuclear station (FDAKE) type EPR 1700 MWe series in a highly restrictive environment due to to the large number of particular requirements from the final customer and the meager degree of progress of the design to the date of commencement of construction. (Author)

  17. Additive manufacturing techniques for the production of tissue engineering constructs.

    Science.gov (United States)

    Mota, Carlos; Puppi, Dario; Chiellini, Federica; Chiellini, Emo

    2015-03-01

    'Additive manufacturing' (AM) refers to a class of manufacturing processes based on the building of a solid object from three-dimensional (3D) model data by joining materials, usually layer upon layer. Among the vast array of techniques developed for the production of tissue-engineering (TE) scaffolds, AM techniques are gaining great interest for their suitability in achieving complex shapes and microstructures with a high degree of automation, good accuracy and reproducibility. In addition, the possibility of rapidly producing tissue-engineered constructs meeting patient's specific requirements, in terms of tissue defect size and geometry as well as autologous biological features, makes them a powerful way of enhancing clinical routine procedures. This paper gives an extensive overview of different AM techniques classes (i.e. stereolithography, selective laser sintering, 3D printing, melt-extrusion-based techniques, solution/slurry extrusion-based techniques, and tissue and organ printing) employed for the development of tissue-engineered constructs made of different materials (i.e. polymeric, ceramic and composite, alone or in combination with bioactive agents), by highlighting their principles and technological solutions. Copyright © 2012 John Wiley & Sons, Ltd.

  18. Alternative Fuels DISI Engine Research ? Autoignition Metrics.

    Energy Technology Data Exchange (ETDEWEB)

    Sjoberg, Carl Magnus Goran [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Vuilleumier, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2018-02-01

    Improved engine efficiency is required to comply with future fuel economy standards. Alternative fuels have the potential to enable more efficient engines while addressing concerns about energy security. This project contributes to the science base needed by industry to develop highly efficient direct injection spark igniton (DISI) engines that also beneficially exploit the different properties of alternative fuels. Here, the emphasis is on quantifying autoignition behavior for a range of spark-ignited engine conditions, including directly injected boosted conditions. The efficiency of stoichiometrically operated spark ignition engines is often limited by fuel-oxidizer end-gas autoignition, which can result in engine knock. A fuel’s knock resistance is assessed empirically by the Research Octane Number (RON) and Motor Octane Number (MON) tests. By clarifying how these two tests relate to the autoignition behavior of conventional and alternative fuel formulations, fuel design guidelines for enhanced engine efficiency can be developed.

  19. Summaries of FY 1994 engineering research

    International Nuclear Information System (INIS)

    1994-12-01

    This report documents the Basic Energy Sciences Engineering Research Program for fiscal year 1994; it provides a summary of each of the program projects in addition to a brief program overview. The report is intended to provide staff of Congressional committees, other executive departments, and other DOE offices with substantive program information so as to facilitate governmental overview and coordination of Federal research programs. Of equal importance, its availability facilitates communication of program information to interested research engineers and scientists

  20. Summaries of FY 1994 engineering research

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    This report documents the Basic Energy Sciences Engineering Research Program for fiscal year 1994; it provides a summary of each of the program projects in addition to a brief program overview. The report is intended to provide staff of Congressional committees, other executive departments, and other DOE offices with substantive program information so as to facilitate governmental overview and coordination of Federal research programs. Of equal importance, its availability facilitates communication of program information to interested research engineers and scientists.

  1. Construction Biotechnology: a new area of biotechnological research and applications.

    Science.gov (United States)

    Stabnikov, Viktor; Ivanov, Volodymyr; Chu, Jian

    2015-09-01

    A new scientific and engineering discipline, Construction Biotechnology, is developing exponentially during the last decade. The major directions of this discipline are selection of microorganisms and development of the microbially-mediated construction processes and biotechnologies for the production of construction biomaterials. The products of construction biotechnologies are low cost, sustainable, and environmentally friendly microbial biocements and biogrouts for the construction ground improvement. The microbial polysaccharides are used as admixtures for cement. Microbially produced biodegradable bioplastics can be used for the temporarily constructions. The bioagents that are used in construction biotechnologies are either pure or enrichment cultures of microorganisms or activated indigenous microorganisms of soil. The applications of microorganisms in the construction processes are bioaggregation, biocementation, bioclogging, and biodesaturation of soil. The biotechnologically produced construction materials and the microbially-mediated construction technologies have a lot of advantages in comparison with the conventional construction materials and processes. Proper practical implementations of construction biotechnologies could give significant economic and environmental benefits.

  2. Ten recommendations for software engineering in research.

    Science.gov (United States)

    Hastings, Janna; Haug, Kenneth; Steinbeck, Christoph

    2014-01-01

    Research in the context of data-driven science requires a backbone of well-written software, but scientific researchers are typically not trained at length in software engineering, the principles for creating better software products. To address this gap, in particular for young researchers new to programming, we give ten recommendations to ensure the usability, sustainability and practicality of research software.

  3. Adhesives in Building--Lamination of Structural Timber Beams, Bonding of Cementitious Materials, Bonding of Gypsum Drywall Construction. Proceedings of a Conference of the Building Research Institute, Division of Engineering and Industrial Research (Spring 1960).

    Science.gov (United States)

    National Academy of Sciences - National Research Council, Washington, DC.

    The role of adhesives in building design is discussed. Three major areas are as follows--(1) lamination of structural timber beams, (2) bonding of cementitious materials, and (3) bonding of gypsum drywall construction. Topical coverage includes--(1) structural lamination today, (2) adhesives in use today, (3) new adhesives needed, (4) production…

  4. Computer-aided dental prostheses construction using reverse engineering.

    Science.gov (United States)

    Solaberrieta, E; Minguez, R; Barrenetxea, L; Sierra, E; Etxaniz, O

    2014-01-01

    The implementation of computer-aided design/computer-aided manufacturing (CAD/CAM) systems with virtual articulators, which take into account the kinematics, constitutes a breakthrough in the construction of customised dental prostheses. This paper presents a multidisciplinary protocol involving CAM techniques to produce dental prostheses. This protocol includes a step-by-step procedure using innovative reverse engineering technologies to transform completely virtual design processes into customised prostheses. A special emphasis is placed on a novel method that permits a virtual location of the models. The complete workflow includes the optical scanning of the patient, the use of reverse engineering software and, if necessary, the use of rapid prototyping to produce CAD temporary prostheses.

  5. Studies on engineering technologies in the Mizunami Underground Research Laboratory. FY 2007 (Contract research)

    International Nuclear Information System (INIS)

    Noda, Masaru; Suyama, Yasuhiro; Nobuto, Jun; Ijiri, Yuji; Mikake, Shinichiro; Matsui, Hiroya

    2009-07-01

    The Mizunami Underground Research Laboratory (MIU) of the Japan Atomic Energy Agency is a major site for geoscientific research to advance the scientific and technological basis for geological disposal of high-level radioactive waste in crystalline rock. Studies on relevant engineering technologies in the MIU consist of a) research on design and construction technology for very deep underground applications, and b) research on engineering technology as a basis of geological disposal. In the Second Phase of the MIU project (the construction phase), engineering studies have focused on research into design and construction technologies for deep underground. The main subjects in the study of very deep underground structures consist of the following: 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction'. In the FY 2007 studies, identification and evaluation of the subjects for study of engineering technologies in the construction phase were carried out to optimize future research work. Specific studies included: validation of the existing design methodology based on data obtained during construction; validation of existing and supplementary rock excavation methods for very deep shafts; estimation of rock stability under high differential water pressures, methodology on long-term maintenance of underground excavations and risk management systems for construction of underground structures have been performed. Based on these studies, future research focused on the four subject areas, which are 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction', has been identified. The design methodology in the first phase of the MIU Project (surface-based investigation phase) was verified to

  6. 48 CFR 36.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 36.209 Section 36.209 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 36.209 Construction contracts with architect-engineer firms. No...

  7. 48 CFR 1436.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 1436.209 Section 1436.209 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1436.209 Construction contracts with architect-engineer...

  8. 48 CFR 436.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 436.209 Section 436.209 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 436.209 Construction contracts with architect-engineer...

  9. 48 CFR 636.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 636.209 Section 636.209 Federal Acquisition Regulations System DEPARTMENT OF STATE SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 636.209 Construction contracts with architect-engineer firms. The...

  10. 48 CFR 2936.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 2936.209 Section 2936.209 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL CONTRACTING REQUIREMENTS CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 2936.209 Construction contracts with architect-engineer firms. As...

  11. 48 CFR 1536.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... architect-engineer firms. 1536.209 Section 1536.209 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Special Aspects of Contracting for Construction 1536.209 Construction contracts with architect-engineer firms. (a...

  12. 76 FR 58155 - Defense Federal Acquisition Regulation Supplement; Construction and Architect-Engineer Services...

    Science.gov (United States)

    2011-09-20

    ... Federal Acquisition Regulation Supplement; Construction and Architect-Engineer Services Performance... performance evaluations for construction and architect-engineer services. DATES: Effective Date: September 20... past performance for construction and Architect- Engineer services. On April 19, 2011, DoD published a...

  13. Tracer research in process engineering

    International Nuclear Information System (INIS)

    Iller, E.

    1992-01-01

    The book is a review of modern applications of tracer techniques in chemical and process engineering studies. The next topics have been extensively presented: 1) media flow through apparatus; 2) the tracers in the study of media flow dynamics through apparatus; 3) mathematical interpretation of experimental data from impulse-response method; 4) the models of media flow through chemical reactors and apparatus; 5) radiotracers in mass transport study; 6) examples of practical applications of tracer methods in industrial objects. 84 refs, 96 figs, 31 tabs

  14. Research Trends on Benefits of Implementing Constructability, Operability, and Maintainability

    Directory of Open Access Journals (Sweden)

    Kordestani Ghaleenoe, N.

    2017-07-01

    Full Text Available Despite allocating huge budgets to civil engineering projects, detailed planning, and employing human resources, project managers still face time, cost, and quality constraints. Most of these challenges are due to a lack of integration of different project phases and the limitations of the presence of construction and maintenance contractors in the initial stages of the project. Considering the benefits of applying constructability, operability, and maintainability (COM concepts, many problems caused by lack of coordination, or duplications and weakness in management, and also time and extra costs due to lack of presence of construction and maintenance contractors in the early stages of the project are resolvable. In this regard, various studies have investigated the benefits of applying these concepts; however, there has been no comprehensive analysis of the benefits of COM. As a result of focus on the benefits of implementation of these concepts and evaluating the effect of each of these strategies and benefits, from different perspectives during various time periods, managers can increase project efficiency and productivity, and improve their performance, through using concepts and strategies of their implementation. This research aims to evaluate the trend of studies on the benefits of implementing constructability, operability, and maintainability in the construction industry. For that, the in-depth literature review method is applied. For qualitative analysis of the obtained information, descriptive analysis has been used. Then, the data was coded, and classified using Excel Software for quantitative data analysis. Finally, the charts presented were evaluated according to the classified fields of study. The necessity of performing such a study is significant because of the fact that a large share of a project’s problems, such as lack of plans’ integration and weakness of administrative system, and increasing time and cost, are due to

  15. Research Collaborations | College of Engineering & Applied Science

    Science.gov (United States)

    Electrical Engineering Instructional Laboratories Student Resources Industrial & Manufacturing Engineering Industrial & Manufacturing Engineering Academic Programs Industrial & Manufacturing Engineering Major Industrial & Manufacturing Engineering Minor Industrial & Manufacturing Engineering

  16. Mechanical Engineering Department engineering research: Annual report, FY 1986

    International Nuclear Information System (INIS)

    Denney, R.M.; Essary, K.L.; Genin, M.S.; Highstone, H.H.; Hymer, J.D.; Taft, S.O.

    1986-12-01

    This report provides information on the five areas of research interest in LLNL's Mechanical Engineering Department. In Computer Code Development, a solid geometric modeling program is described. In Dynamic Systems and Control, structure control and structure dynamics are discussed. Fabrication technology involves machine cutting, interferometry, and automated optical component manufacturing. Materials engineering reports on composite material research and measurement of molten metal surface properties. In Nondestructive Evaluation, NMR, CAT, and ultrasound machines are applied to manufacturing processes. A model for underground collapse is developed. Finally, an alternative heat exchanger is investigated for use in a fusion power plant. Separate abstracts were prepared for each of the 13 reports in this publication

  17. Conformity Assessment as a Tool for Organizational Learning in Large Engineering and Construction Projects

    Directory of Open Access Journals (Sweden)

    Luciano Assalim

    2013-05-01

    Full Text Available For the successful realization of large engineering and construction projects (LECPs, a systemic organizational learning framework for institutional cooperation is critical. Due to the long project life-cycle of LECPs, this is particularly important for this kind of project. The objective of this paper is to analyze to what extent the conformity assessment of LECPs, carried out under Engineering, Procurement and Construction management (EPCm services, can be used as a tool for organizational learning and cooperation between typical stakeholders (project owners, engineering contractors, EPC contractors; subcontractors and certification bodies. The research, from which this paper emanates, was based on a case study concerning LECPs in an oil and gas company in Brazil. Based on its results, we suggest that the proposed organizational learning framework, supported by the conformity assessment rationale, constitutes an important management tool that can be disseminated in other organizational contexts where conformity assessments of LECPs take place.

  18. New technologies in Islamic countries. Power engineering, transport, oil industry, machinery construction, building construction and information technologies problems

    International Nuclear Information System (INIS)

    Sharipova, N.S.

    1999-01-01

    The published proceedings contain brief presentations concerning new technologies in power engineering, transport, oil industry, machinery construction, building construction and information technologies presented to the International scientific and technical conference: New technologies in Islamic countries, which was organized within frame work of 6 General Assembly of Federation of engineering Institutes of Islamic countries (FEIIC). (author)

  19. New technologies in Islamic countries. Power engineering, transport, oil industry, machinery construction, building construction and information technologies problems

    International Nuclear Information System (INIS)

    Sharipova, N.S.

    1999-01-01

    This issue contains papers, which reflect the most important achievements of new technologies in power engineering, transport, oil industry, machinery construction, building construction and information technologies presented to the International Scientific and Technical Conference: New technologies in Islamic countries, which was organized within frame work of 6 General Assembly of Federation of Engineering Institutes of Islamic Countries (FEIIC). (author)

  20. Constructal Theory Of Design In Engineering And Nature

    Directory of Open Access Journals (Sweden)

    Adrian Bejan

    2005-02-01

    Full Text Available This is a brief introduction to an engineering theory on the origin and generation of geometric form in all flow systems: the animate, the inanimate and the engineered. The theory is named constructal, and is based on the thought that it is natural for currents to construct for themselves in time paths of greater flow access. It is shown that this process of flow path optimization can be reasoned on the basis of principle: the maximization of global performance subject to finite-size constraints. One example is the generation of tree-shaped flow patterns, as paths of least resistance between one point (source, sink and an infinity of points (area, volume, as in the circulatory, respiratory and nervous systems. An other is the generation of regular spacings in heat generating volumes, such as swarms of honeybees. The optimized tree-flow geometries account for allometric laws, e. g., the relationship between the total tube contact area and the body size, the proportionality between metabolic rate and body size raised to the power 3/4, the proportionality between breathing and heartbeating times and body size raised to the power 1/4, and the proportionality between the cruising speed of flying bodies (insects, birds, airplanes and body mass raised to the power 1/6. The optimized flow structures constitute robust designs, and robustness improves as the complexity of the system increases. Flow architectures that are more efficient look more natural.

  1. Detonation Engine Research Facility (DERF)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: This facility is configured to safely conduct experimental pressuregain combustion research. The DERF is capable of supporting up to 60,000 lbf thrust...

  2. Domain Engineering, A Software Engineering Discipline in Need of Research

    DEFF Research Database (Denmark)

    Bjørner, Dines

    2000-01-01

    . The aim of this paper is to advocate: that researchers study these development method components, and that universities focus their education on basing well-nigh any course on the use of formal techniques: Specification and verification, and that software engineers take heed: Start applying formal......, and these again seem more stable than software designs. Thus, almost like the universal laws of physics, it pays off to first develop theories of domains. But domain engineering, as in fact also requirements engineering, really is in need of thoroughly researched development principles, techniques and tools...... techniques. A brief example of describing stake-holder perspectives will be given - on the background of which we then proceed to survey the notions of domain intrinsics, domain support technologies, domain management & organisation, domain rules & regulations, domain human behaviour, etc. We show elsewhere...

  3. Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer

    Directory of Open Access Journals (Sweden)

    Walchli John

    2009-04-01

    Full Text Available Abstract Background With the goal of improving yield and success rates of heterologous protein production for structural studies we have developed the database and algorithm software package Gene Composer. This freely available electronic tool facilitates the information-rich design of protein constructs and their engineered synthetic gene sequences, as detailed in the accompanying manuscript. Results In this report, we compare heterologous protein expression levels from native sequences to that of codon engineered synthetic gene constructs designed by Gene Composer. A test set of proteins including a human kinase (P38α, viral polymerase (HCV NS5B, and bacterial structural protein (FtsZ were expressed in both E. coli and a cell-free wheat germ translation system. We also compare the protein expression levels in E. coli for a set of 11 different proteins with greatly varied G:C content and codon bias. Conclusion The results consistently demonstrate that protein yields from codon engineered Gene Composer designs are as good as or better than those achieved from the synonymous native genes. Moreover, structure guided N- and C-terminal deletion constructs designed with the aid of Gene Composer can lead to greater success in gene to structure work as exemplified by the X-ray crystallographic structure determination of FtsZ from Bacillus subtilis. These results validate the Gene Composer algorithms, and suggest that using a combination of synthetic gene and protein construct engineering tools can improve the economics of gene to structure research.

  4. Gene composer: database software for protein construct design, codon engineering, and gene synthesis.

    Science.gov (United States)

    Lorimer, Don; Raymond, Amy; Walchli, John; Mixon, Mark; Barrow, Adrienne; Wallace, Ellen; Grice, Rena; Burgin, Alex; Stewart, Lance

    2009-04-21

    To improve efficiency in high throughput protein structure determination, we have developed a database software package, Gene Composer, which facilitates the information-rich design of protein constructs and their codon engineered synthetic gene sequences. With its modular workflow design and numerous graphical user interfaces, Gene Composer enables researchers to perform all common bio-informatics steps used in modern structure guided protein engineering and synthetic gene engineering. An interactive Alignment Viewer allows the researcher to simultaneously visualize sequence conservation in the context of known protein secondary structure, ligand contacts, water contacts, crystal contacts, B-factors, solvent accessible area, residue property type and several other useful property views. The Construct Design Module enables the facile design of novel protein constructs with altered N- and C-termini, internal insertions or deletions, point mutations, and desired affinity tags. The modifications can be combined and permuted into multiple protein constructs, and then virtually cloned in silico into defined expression vectors. The Gene Design Module uses a protein-to-gene algorithm that automates the back-translation of a protein amino acid sequence into a codon engineered nucleic acid gene sequence according to a selected codon usage table with minimal codon usage threshold, defined G:C% content, and desired sequence features achieved through synonymous codon selection that is optimized for the intended expression system. The gene-to-oligo algorithm of the Gene Design Module plans out all of the required overlapping oligonucleotides and mutagenic primers needed to synthesize the desired gene constructs by PCR, and for physically cloning them into selected vectors by the most popular subcloning strategies. We present a complete description of Gene Composer functionality, and an efficient PCR-based synthetic gene assembly procedure with mis-match specific endonuclease

  5. Gene Composer: database software for protein construct design, codon engineering, and gene synthesis

    Directory of Open Access Journals (Sweden)

    Mixon Mark

    2009-04-01

    Full Text Available Abstract Background To improve efficiency in high throughput protein structure determination, we have developed a database software package, Gene Composer, which facilitates the information-rich design of protein constructs and their codon engineered synthetic gene sequences. With its modular workflow design and numerous graphical user interfaces, Gene Composer enables researchers to perform all common bio-informatics steps used in modern structure guided protein engineering and synthetic gene engineering. Results An interactive Alignment Viewer allows the researcher to simultaneously visualize sequence conservation in the context of known protein secondary structure, ligand contacts, water contacts, crystal contacts, B-factors, solvent accessible area, residue property type and several other useful property views. The Construct Design Module enables the facile design of novel protein constructs with altered N- and C-termini, internal insertions or deletions, point mutations, and desired affinity tags. The modifications can be combined and permuted into multiple protein constructs, and then virtually cloned in silico into defined expression vectors. The Gene Design Module uses a protein-to-gene algorithm that automates the back-translation of a protein amino acid sequence into a codon engineered nucleic acid gene sequence according to a selected codon usage table with minimal codon usage threshold, defined G:C% content, and desired sequence features achieved through synonymous codon selection that is optimized for the intended expression system. The gene-to-oligo algorithm of the Gene Design Module plans out all of the required overlapping oligonucleotides and mutagenic primers needed to synthesize the desired gene constructs by PCR, and for physically cloning them into selected vectors by the most popular subcloning strategies. Conclusion We present a complete description of Gene Composer functionality, and an efficient PCR-based synthetic gene

  6. [Construction of injectable tissue engineered nucleus pulposus in vitro].

    Science.gov (United States)

    Tian, Huake; Wang, Jian; Chen, Chao; Liu, Jie; Zhou, Yue

    2009-02-01

    To investigate the feasibility of using thermo-sensitive chitosan hydrogen as a scaffold to construct tissue engineered injectable nucleus pulposus (NP). Three-month-old neonatal New Zealand rabbits (male or female) weighing 150-200 g were selected to isolate and culture NP cells. The thermo-sensitive chitosan hydrogel scaffold was made of chitosan, disodium beta-glycerophosphate and hydroxyethyl cellulose. Its physical properties and gross condition were observed. The tissue engineered NP was constructed by compounding the scaffold and rabbit NP cells. Then, the viability of NP cells in the chitosan hydrogel was observed 2 days after compound culture and the growth condition of NP cells on the scaffold was observed by SEM 7 days after compound culture. NP cells went through histology and immunohistochemistry detection and their secretion of aggrecan and expression of Col II mRNA were analyzed by RT-PCR 21 days after compound culture. The thermo-sensitive chitosan hydrogel was liquid at room temperature and solidified into gel at 37 degrees C (15 minutes) due to crosslinking reaction. Acridine orange-propidium iodide staining showed that the viability rate of NP cells in chitosan hydrogel was above 90%. Scanning electron microscope observation demonstrated that the NP cells were distributed in the reticulate scaffold, with ECM on their surfaces. The results of HE, toluidine blue, safranin O and histology and immunohistochemistry staining confirmed that the NP cells in chitosan hydrogel were capable of producing ECM. RT-PCR results showed that the secretion of Col II and aggrecan mRNA in NP cells cultured three-dimensionally by chitosan hydrogen scaffold were 0.631 +/- 0.064 and 0.832 +/- 0.052, respectively, showing more strengths of producing matrix than that of monolayer culture (0.528 +/- 0.039, 0.773 +/- 0.046) with a significant difference (P compound culture, and may be a potential NP cells carrier for tissue engineered NP.

  7. Electronics engineering research proposals for FY78

    International Nuclear Information System (INIS)

    Cleland, L.L.; Ekstrom, M.P.; Miller, E.K.

    1977-01-01

    Since most of the Electronics Engineering Research expenditures are in the Engineering Research Division (ERD), the two are inseparable when discussing plans. A reorganization of ERD aimed at further expanding LLL capabilities and being more responsive to LLL needs is now complete. Six discipline related groups constitute the research elements in ERD. Three groups remained unchanged, one group was modified slightly, two groups were added, and one group was dissolved. The technical activities of each of the six research-oriented groups within ERD are reported

  8. Biomedical engineering for health research and development.

    Science.gov (United States)

    Zhang, X-Y

    2015-01-01

    Biomedical engineering is a new area of research in medicine and biology, providing new concepts and designs for the diagnosis, treatment and prevention of various diseases. There are several types of biomedical engineering, such as tissue, genetic, neural and stem cells, as well as chemical and clinical engineering for health care. Many electronic and magnetic methods and equipments are used for the biomedical engineering such as Computed Tomography (CT) scans, Magnetic Resonance Imaging (MRI) scans, Electroencephalography (EEG), Ultrasound and regenerative medicine and stem cell cultures, preparations of artificial cells and organs, such as pancreas, urinary bladders, liver cells, and fibroblasts cells of foreskin and others. The principle of tissue engineering is described with various types of cells used for tissue engineering purposes. The use of several medical devices and bionics are mentioned with scaffold, cells and tissue cultures and various materials are used for biomedical engineering. The use of biomedical engineering methods is very important for the human health, and research and development of diseases. The bioreactors and preparations of artificial cells or tissues and organs are described here.

  9. Reengineering Biomedical Translational Research with Engineering Ethics.

    Science.gov (United States)

    Sunderland, Mary E; Nayak, Rahul Uday

    2015-08-01

    It is widely accepted that translational research practitioners need to acquire special skills and knowledge that will enable them to anticipate, analyze, and manage a range of ethical issues. While there is a small but growing literature that addresses the ethics of translational research, there is a dearth of scholarship regarding how this might apply to engineers. In this paper we examine engineers as key translators and argue that they are well positioned to ask transformative ethical questions. Asking engineers to both broaden and deepen their consideration of ethics in their work, however, requires a shift in the way ethics is often portrayed and perceived in science and engineering communities. Rather than interpreting ethics as a roadblock to the success of translational research, we suggest that engineers should be encouraged to ask questions about the socio-ethical dimensions of their work. This requires expanding the conceptual framework of engineering beyond its traditional focus on "how" and "what" questions to also include "why" and "who" questions to facilitate the gathering of normative, socially-situated information. Empowering engineers to ask "why" and "who" questions should spur the development of technologies and practices that contribute to improving health outcomes.

  10. FY08 Engineering Research and Technology Report

    Energy Technology Data Exchange (ETDEWEB)

    Minichino, C; McNichols, D

    2009-02-24

    This report summarizes the core research, development, and technology accomplishments in Lawrence Livermore National Laboratory's Engineering Directorate for FY2008. These efforts exemplify Engineering's more than 50-year history of developing and applying the technologies needed to support the Laboratory's national security missions. A partner in every major program and project at the Laboratory throughout its existence, Engineering has prepared for this role with a skilled workforce and technical resources developed through both internal and external venues. These accomplishments embody Engineering's mission: 'Enable program success today and ensure the Laboratory's vitality tomorrow.' Engineering's mission is carried out through basic research and technology development. Research is the vehicle for creating competencies that are cutting-edge, or require discovery-class groundwork to be fully understood. Our technology efforts are discipline-oriented, preparing research breakthroughs for broader application to a variety of Laboratory needs. The term commonly used for technology-based projects is 'reduction to practice.' As we pursue this two-pronged approach, an enormous range of technological capabilities result. This report combines our work in research and technology into one volume, organized into thematic technical areas: Engineering Modeling and Simulation; Measurement Technologies; Micro/Nano-Devices and Structures; Engineering Systems for Knowledge and Inference; and Energy Manipulation. Our investments in these areas serve not only known programmatic requirements of today and tomorrow, but also anticipate the breakthrough engineering innovations that will be needed in the future.

  11. Plant Engineering and Construction System with Knowledge Management: A Case Study in NPP Construction in Hitachi-GE NE

    International Nuclear Information System (INIS)

    Mochida, T.; Hamamoto, M.; Nakamitsu, N.

    2016-01-01

    Full text: Hitachi-GE Nuclear Energy, Ltd. (HGNE) has more than 40 years BWR plants construction experience. The company continues to develop plant engineering system and plant construction systems based on the experience and the lessons learned. Currently, these systems are integrated in a variety of knowledge bases using the latest information technology (IT). Their performance is continuously validated in the recent NPP constructions. Typical examples are shown as case studies for knowledge management. These plant engineering and construction management systems are essential to achieve the on-time and on-budget-goals in NPP construction projects. (author

  12. 2016 Milwaukee Engineering Research Conference | College of Engineering &

    Science.gov (United States)

    Biomedical Engineering Concentration on Ergonomics M.S. Program in Computer Science Interdisciplinary Concentration on Energy Doctoral Programs in Engineering Non-Degree Candidate Departments Biomedical Engineering Biomedical Engineering Industry Advisory Council Civil & Environmental Engineering Civil &

  13. Nanoscale Science, Engineering and Technology Research Directions

    Energy Technology Data Exchange (ETDEWEB)

    Lowndes, D. H.; Alivisatos, A. P.; Alper, M.; Averback, R. S.; Jacob Barhen, J.; Eastman, J. A.; Imre, D.; Lowndes, D. H.; McNulty, I.; Michalske, T. A.; Ho, K-M; Nozik, A. J.; Russell, T. P.; Valentin, R. A.; Welch, D. O.; Barhen, J.; Agnew, S. R.; Bellon, P.; Blair, J.; Boatner, L. A.; Braiman, Y.; Budai, J. D.; Crabtree, G. W.; Feldman, L. C.; Flynn, C. P.; Geohegan, D. B.; George, E. P.; Greenbaum, E.; Grigoropoulos, C.; Haynes, T. E.; Heberlein, J.; Hichman, J.; Holland, O. W.; Honda, S.; Horton, J. A.; Hu, M. Z.-C.; Jesson, D. E.; Joy, D. C.; Krauss, A.; Kwok, W.-K.; Larson, B. C.; Larson, D. J.; Likharev, K.; Liu, C. T.; Majumdar, A.; Maziasz, P. J.; Meldrum, A.; Miller, J. C.; Modine, F. A.; Pennycook, S. J.; Pharr, G. M.; Phillpot, S.; Price, D. L.; Protopopescu, V.; Poker, D. B.; Pui, D.; Ramsey, J. M.; Rao, N.; Reichl, L.; Roberto, J.; Saboungi, M-L; Simpson, M.; Strieffer, S.; Thundat, T.; Wambsganss, M.; Wendleken, J.; White, C. W.; Wilemski, G.; Withrow, S. P.; Wolf, D.; Zhu, J. H.; Zuhr, R. A.; Zunger, A.; Lowe, S.

    1999-01-01

    This report describes important future research directions in nanoscale science, engineering and technology. It was prepared in connection with an anticipated national research initiative on nanotechnology for the twenty-first century. The research directions described are not expected to be inclusive but illustrate the wide range of research opportunities and challenges that could be undertaken through the national laboratories and their major national scientific user facilities with the support of universities and industry.

  14. A Research Agenda for Security Engineering

    Directory of Open Access Journals (Sweden)

    Rich Goyette

    2013-08-01

    Full Text Available Despite nearly 30 years of research and application, the practice of information system security engineering has not yet begun to exhibit the traits of a rigorous scientific discipline. As cyberadversaries have become more mature, sophisticated, and disciplined in their tradecraft, the science of security engineering has not kept pace. The evidence of the erosion of our digital security – upon which society is increasingly dependent – appears in the news almost daily. In this article, we outline a research agenda designed to begin addressing this deficit and to move information system security engineering toward a mature engineering discipline. Our experience suggests that there are two key areas in which this movement should begin. First, a threat model that is actionable from the perspectives of risk management and security engineering should be developed. Second, a practical and relevant security-measurement framework should be developed to adequately inform security-engineering and risk-management processes. Advances in these areas will particularly benefit business/government risk assessors as well as security engineers performing security design work, leading to more accurate, meaningful, and quantitative risk analyses and more consistent and coherent security design decisions. Threat modelling and security measurement are challenging activities to get right – especially when they need to be applied in a general context. However, these are decisive starting points because they constitute the foundation of a scientific security-engineering practice. Addressing these challenges will require stronger and more coherent integration between the sub-disciplines of risk assessment and security engineering, including new tools to facilitate that integration. More generally, changes will be required in the way security engineering is both taught and practiced to take into account the holistic approach necessary from a mature, scientific

  15. Biomedical engineering frontier research and converging technologies

    CERN Document Server

    Jun, Ho-Wook; Shin, Jennifer; Lee, SangHoon

    2016-01-01

    This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly dependent on new ideas and tools from other disciplines, the paradigm shift caused by technological innovations in the fields of information science, nanotechnology, and robotics is opening new opportunities in healthcare, besides dramatically changing the ways we actually practice science. At the same time, a new generation of engineers, fluent in many different scientific “languages,” is creating entirely new fields of research that approach the “old” questions f...

  16. Electronics Engineering Research. Final report, FY 1979

    International Nuclear Information System (INIS)

    Weissenberger, S.

    1980-01-01

    Accomplishments in Electronics Engineering Research (EER) during FY79 spanned a broad range of technologies, from high-speed microelectronics to digital image enhancement; from underground probing with electromagnetic waves to detecting neutrons with a small solid-state device; and from computer systems to aid engineers, to software tools to aid programmers. This report describes the overall EER program and its objectives, summarizes progress made in FY79, and outlines plans for FY80

  17. Council of Energy Engineering Research. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Goldstein, Richard J.

    2003-08-22

    The Engineering Research Program, a component program of the DOE Office of Basic Energy Sciences (BES), was established in 1979 to aid in resolving the numerous engineering issues arising from efforts to meet U.S. energy needs. The major product of the program became part of the body of knowledge and data upon which the applied energy technologies are founded; the product is knowledge relevant to energy exploration, production, conversion and use.

  18. Sustainable Construction for Urban Infill Development Using Engineered Massive Wood Panel Systems

    Directory of Open Access Journals (Sweden)

    Steffen Lehmann

    2012-10-01

    Full Text Available Prefabricated engineered solid wood panel construction systems can sequester and store CO2. Modular cross-laminated timber (CLT, also called cross-lam panels form the basis of low-carbon, engineered construction systems using solid wood panels that can be used to build residential infill developments of 10 storeys or higher. Multi-apartment buildings of 4 to 10 storeys constructed entirely in timber, such as recently in Europe, are innovative, but their social and cultural acceptance in Australia and North America is at this stage still uncertain. Future commercial utilisation is only possible if there is a user acceptance. The author is part of a research team that aims to study two problems: first models of urban infill; then focus on how the use of the CLT systems can play an important role in facilitating a more livable city with better models of infill housing. Wood is an important contemporary building resource due to its low embodied energy and unique attributes. The potential of prefabricated engineered solid wood panel systems, such as CLT, as a sustainable building material and system is only just being realised around the globe. Since timber is one of the few materials that has the capacity to store carbon in large quantities over a long period of time, solid wood panel construction offers the opportunity of carbon engineering, to turn buildings into ‘carbon sinks’. Thus some of the historically negative environmental impact of urban development and construction can be turned around with CLT construction on brownfield sites.

  19. Aircraft Turbine Engine Control Research at NASA Glenn Research Center

    Science.gov (United States)

    Garg, Sanjay

    2014-01-01

    This lecture will provide an overview of the aircraft turbine engine control research at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC). A brief introduction to the engine control problem is first provided with a description of the current state-of-the-art control law structure. A historical aspect of engine control development since the 1940s is then provided with a special emphasis on the contributions of GRC. The traditional engine control problem has been to provide a means to safely transition the engine from one steady-state operating point to another based on the pilot throttle inputs. With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Branch (CDB) at GRC is leading and participating in various projects in partnership with other organizations within GRC and across NASA, other government agencies, the U.S. aerospace industry, and academia to develop advanced propulsion controls and diagnostics technologies that will help meet the challenging goals of NASA programs under the Aeronautics Research Mission. The second part of the lecture provides an overview of the various CDB technology development activities in aircraft engine control and diagnostics, both current and some accomplished in the recent past. The motivation for each of the research efforts, the research approach, technical challenges and the key progress to date are summarized. The technologies to be discussed include system level engine control concepts, gas path diagnostics, active component control, and distributed engine control architecture. The lecture will end with a futuristic perspective of how the various current technology developments will lead to an Intelligent and Autonomous Propulsion System requiring none to very minimum pilot interface

  20. 48 CFR 31.201-7 - Construction and architect-engineer contracts.

    Science.gov (United States)

    2010-10-01

    ...-engineer contracts. 31.201-7 Section 31.201-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Organizations 31.201-7 Construction and architect-engineer contracts. Specific principles and procedures for... architect-engineer contracts related to construction projects, are in 31.105. The applicability of these...

  1. Mechanical Engineering Department engineering research: Annual report, FY 1986

    Energy Technology Data Exchange (ETDEWEB)

    Denney, R.M.; Essary, K.L.; Genin, M.S.; Highstone, H.H.; Hymer, J.D.; Taft, S.O. (eds.)

    1986-12-01

    This report provides information on the five areas of research interest in LLNL's Mechanical Engineering Department. In Computer Code Development, a solid geometric modeling program is described. In Dynamic Systems and Control, structure control and structure dynamics are discussed. Fabrication technology involves machine cutting, interferometry, and automated optical component manufacturing. Materials engineering reports on composite material research and measurement of molten metal surface properties. In Nondestructive Evaluation, NMR, CAT, and ultrasound machines are applied to manufacturing processes. A model for underground collapse is developed. Finally, an alternative heat exchanger is investigated for use in a fusion power plant. Separate abstracts were prepared for each of the 13 reports in this publication. (JDH)

  2. Innovation and Research on Engineering Education

    DEFF Research Database (Denmark)

    de Graaff, Erik; Kolmos, Anette

    2014-01-01

    Our Western society depends strongly on continuous technological innovation. Engineers, the designers of the future technology need extensive competencies to face the challenge of dealing with ever increasing complexity. In some areas more than half the knowledge they learn in University is obsol......Our Western society depends strongly on continuous technological innovation. Engineers, the designers of the future technology need extensive competencies to face the challenge of dealing with ever increasing complexity. In some areas more than half the knowledge they learn in University...... is obsolete by the time the enter practice. Recognition of these issues has recently resulted in worldwide increase of attention for innovation of engineering education. This chapter presents a brief outline of the traditions in higher engineering education culminating in the stage of research and development...... in the last century. Next, the recent revival of engineering education research is described, contrasting the developments in the USA with Europe and the rest of the world. The efforts in the USA appear to follow Boyer’s concept scholarship of teaching, and aim for the establishment of engineering education...

  3. Constructing Learning-by-Doing Pedagogical Model for Delivering 21st Century Engineering Education

    Directory of Open Access Journals (Sweden)

    Ghassan Frache

    2018-01-01

    Full Text Available The United Arab Emirates (UAE is dedicated to establishing the best teaching and learning environment for students and staff across all higher education institutions. To heed this call, the engineering division adopted the Learning-by-Doing (LBD pedagogical philosophy for 21st Century education at the heart of its strategic directions. This study intends to explore how LBD is understood and practiced in UAE colleges and how 21st Century skills can be explicitly incorporated into its engineering curriculum by using constructive alignment as a pattern for instructional design. This work intends to investigate the general question: “What constructively aligned Learning-by-Doing pedagogical model, with the incorporation of 21st Century skills, needs to be developed to effectively teach and prepare engineering students at the Higher College of Technology, UAE for successful long-term employment in the global working economy?”. Using mixed method research design and input from its major stakeholders, student survey questionnaires, engineering instructors and dean structured interviews, overt class observation and syllabi examination have all been utilized for data triangulation. In conclusion, the study developed a collaborative LBD model tailor-fitted to the institution’s engineering program and to UAE’s culture.

  4. The progress of Requirements Engineering research

    Directory of Open Access Journals (Sweden)

    Michael Terstine

    2015-06-01

    Full Text Available This article is describes the path through the process of Requirements Engineering research and some lines are identified that can meet the needs of the emerging software and the complexity of today's problems. First is done a reviews to the state of the art of research in this area, with regard to technologies developed to address requirements specific tasks, such as elicitation, modeling and analysis. This review identified areas for further research. Subsequently, several strategies are described to implement and extend the results, in order to help shape the scope of future research. Finally, some topics for future research are proposed in order to address the Requirements Engineering needed to respond to emerging systems and the complexity of the same.

  5. Summaries of FY 1996 engineering research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    This report documents the Basic Energy Sciences (BES) Engineering Research Program for fiscal year 1996; it provides a summary for each of the program projects in addition to a brief program overview. The report is intended to provide staff of Congressional committees, other executive departments, and other DOE offices with substantive program information so as to facilitate governmental overview and coordination of Federal research programs. Of equal importance, its availability facilitates communication of program information to interested research engineers and scientists. Each BES Division administers basic, mission oriented research programs in the area indicated by its title. The BES Engineering Research Program is one such program; it is administered by the Engineering and Geosciences Division of BES. In preparing this report the principal investigators were asked to submit summaries for their projects that were specifically applicable to fiscal year 1996. The summaries received have been edited if necessary, but the press for timely publication made it impractical to have the investigators review and approve the revised summaries prior to publication. For more information about a given project, it is suggested that the investigators be contacted directly.

  6. Using ethnographic methods in software engineering research

    DEFF Research Database (Denmark)

    Sharp, Helen, C.; Dittrich, Yvonne; De Souza, Cleidson

    2010-01-01

    This tutorial provides an overview of the role of ethnography in Software Engineering research. It describes the use of ethnographic methods as a means to provide an in-depth understanding of the socio-technological realities surrounding everyday software development practice. The knowledge gained......-depth discussion of methods for data collection and analysis used in ethnographic studies. It then describes how these methods can be and have been used by software engineering researchers to understand developers' work practices, to inform the development of processes, methods and tools and to evaluate...... can be used to improve processes, methods and tools as well as develop observed industrial practices. The tutorial begins with a brief historical account of ethnography in the fields of Software Engineering, CSCW, Information Systems and other related areas. This sets the stage for a more in...

  7. An initial bibliometric analysis and mapping of systems engineering research

    CSIR Research Space (South Africa)

    Oosthuizen, Rudolph

    2016-07-01

    Full Text Available Systems engineering is still a growing field that depends on continuous research to develop and mature. Research in systems engineering is difficult and the classic approaches for other engineering disciplines may not be sufficient. Additional...

  8. 48 CFR 53.236 - Construction and architect-engineer contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 53.236 Section 53.236 Federal Acquisition Regulations System FEDERAL ACQUISITION...-engineer contracts. ...

  9. Quality assurance during construction of civil engineering structures important to safety of nuclear facilities

    International Nuclear Information System (INIS)

    2011-11-01

    The present manual is developed to deal with quality assurance aspect of civil engineering structures in a greater detail. This manual gives detail to develop QA plans specific to multifarious activities of civil engineering construction

  10. Construction and design of solid-propellant rocket engines. Konstruktsiia i proektirovanie raketnykh dvigatelei tverdogo topliva

    Energy Technology Data Exchange (ETDEWEB)

    Fakhrutdinov, I.K.; Kotel' nikov, A.V.

    1987-01-01

    Methods for assessing the durability of different components of solid-propellant rocket engines are presented. The following aspects of engine development are discussed: task formulation, parameter calculation, construction scheme selection, materials, and durability assessment. 45 references.

  11. Engineering Education in Research-Intensive Universities

    Science.gov (United States)

    Alpay, E.; Jones, M. E.

    2012-01-01

    The strengths and weaknesses of engineering education in research-intensive institutions are reported and key areas for developmental focus identified. The work is based on a questionnaire and session summaries used during a two-day international conference held at Imperial College London. The findings highlight several common concerns, such as…

  12. Engineering sciences research highlights. Fiscal year 1983

    International Nuclear Information System (INIS)

    Tucker, E.F.; Dobratz, B.

    1984-05-01

    The Laboratory's overall mission is sixfold. We are charged with developing nuclear warheads for defense, technology for arms control, and new concepts for defense against nuclear attack; with supporting programs for both nonnuclear defense and energy research and development; and with advancing our knowledge of science and technology so that we can respond to other national needs. Major programs in support of this mission involve nuclear weapons, energy, environmental science, and basic research. Specific areas of investigation include the design, development, and testing of nuclear weapons; nuclear safeguards and security; inertial and magnetic fusion and nuclear, solar, fossil, and geothermal energy; and basic research in physics, chemistry, mathematics, engineering, and the computer and life sciences. With the staff and facilities maintained for these and other programs, the Laboratory can respond to specific national needs in virtually all areas of the physical and life sciences. Within the Laboratory's organization, most technical research activities are carried out in three directorates: Engineering Sciences; Physics and Mathematics; and Chemistry, Earth and Life Sciences. The activities highlighted here are examples of unclassified work carried out in the seven divisions that made up the Engineering Sciences Directorate at the end of fiscal year 1983. Brief descriptions of these divisions' goals and capabilities and summaries of selected projects illustrate the diversity of talent, expertise, and facilities maintained within the Engineering Sciences Directorate

  13. Empirical research on constructing Taiwan's ecoenvironmental ...

    African Journals Online (AJOL)

    In this paper, the material flow indicators and ecological footprint approach structured are adopted to construct eco-environmental stress indicators. We use relevant data to proceed with the empirical analyses on environmental stress and ecological impacts in Taiwan between the years of 1998 and 2007. Analysis of ...

  14. PREFACE: International Scientific Conference of Young Scientists: Advanced Materials in Construction and Engineering (TSUAB2014)

    Science.gov (United States)

    Kopanitsa, Natalia O.

    2015-01-01

    In October 15-17, 2014 International Scientific Conference of Young Scientists: Advanced Materials in Construction and Engineering (TSUAB2014) took place at Tomsk State University of Architecture and Building (Tomsk, Russia). The Conference became a discussion platform for researchers in the fields of studying structure and properties of advanced building materials and included open lectures of leading scientists and oral presentations of master, postgraduate and doctoral students. A special session was devoted to reports of school children who further plan on starting a research career. The Conference included an industrial exhibition where companies displayed the products and services they supply. The companies also gave presentations of their products within the Conference sessions.

  15. Federal Funding of Engineering Research and Development, 1980-1984.

    Science.gov (United States)

    American Society of Mechanical Engineers, Washington, DC.

    Data on the sources, amounts, and trends of federal funding for engineering research and development (R&D) are presented for 1980-1984. Narrative highlights are provided for: the total federal funding obligations for engineering R&D, mechanical engineering, astronautical engineering, aeronautical engineering, chemical engineering, civil…

  16. Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering

    NARCIS (Netherlands)

    Silva, J.M.; Georgi, Nicole; Costa, R.; Sher, P.; Reis, R L; van Blitterswijk, Clemens; Karperien, Hermanus Bernardus Johannes; Mano, J.F.

    2013-01-01

    Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and

  17. The Role of Hypothesis in Constructive Design Research

    DEFF Research Database (Denmark)

    Bang, Anne Louise; Krogh, Peter; Ludvigsen, Martin

    2012-01-01

    It is, today, widely appreciated that Research-through-Design – or Constructive Design Research as we will call it in this paper – allows for designers to produce knowledge based on the skills and capacities of the design field itself. However, most of the research fails to bridge the gap between...... the general notions of constructive design research and the detailed research activities of the field. We therefore suggest bridging this methodological gap in the academic discussion with what we have ended up calling the “entrance level of constructive design research”. As a step towards to a more nuanced...... and solid perspective on how to keep constructive design research on track, this paper offers a model for understanding the role of hypothesis in constructive design research. The model allows for understanding the hypothesis’s relation to research motivation, questions, experiments, evaluation...

  18. The Role of Hypothesis in Constructive Design Research

    OpenAIRE

    Bang, Anne Louise; Krogh, Peter; Ludvigsen, Martin; Markussen, Thomas

    2012-01-01

    It is, today, widely appreciated that Research-through-Design – or Constructive Design Research as we will call it in this paper – allows for designers to produce knowledge based on the skills and capacities of the design field itself.However, most of the research fails to bridge the gap between the general notions of constructive design research and the detailed research activities of the field. We therefore suggest bridging this methodological gap in the academic discussion with what we hav...

  19. Final Report: Performance Engineering Research Institute

    Energy Technology Data Exchange (ETDEWEB)

    Mellor-Crummey, John [Rice Univ., Houston, TX (United States)

    2014-10-27

    This document is a final report about the work performed for cooperative agreement DE-FC02-06ER25764, the Rice University effort of Performance Engineering Research Institute (PERI). PERI was an Enabling Technologies Institute of the Scientific Discovery through Advanced Computing (SciDAC-2) program supported by the Department of Energy's Office of Science Advanced Scientific Computing Research (ASCR) program. The PERI effort at Rice University focused on (1) research and development of tools for measurement and analysis of application program performance, and (2) engagement with SciDAC-2 application teams.

  20. Constructing the Value of Information Systems Research

    DEFF Research Database (Denmark)

    Avital, Michel

    2014-01-01

    Building on a social constructivist approach, this commentary examines the value of Information Systems (IS) research and its bearing on the future of the discipline in three steps as follows. First, it is argued that the product of IS scholars can serve as a proxy for IS research and that the su......Building on a social constructivist approach, this commentary examines the value of Information Systems (IS) research and its bearing on the future of the discipline in three steps as follows. First, it is argued that the product of IS scholars can serve as a proxy for IS research...

  1. CNG INJECTOR RESEARCH FOR DUAL FUEL ENGINE

    Directory of Open Access Journals (Sweden)

    Adam Majczak

    2017-03-01

    Full Text Available The article presents the tests results of the prototype design of hydraulically assisted injector, that is designed for gas supply into diesel engines. The construction of the injector allows for it positioning in the glow plug socket, so that the gas is injected directly into the combustion chamber. The cycle analysis of the four-cylinder Andoria ADCR engine with a capacity of 2.6 dm3 for different crankshaft rotational speeds allowed to determine the necessary time for fuel injection. Because of that, it was possible to determine the required mass flow rate of the injector, for replacing as much of the original fuel by gaseous fuel. To ensure a high value of flow inside the injector, supply pressure equal to 1 MPa was applied. High gas supply pressure requires high value of valve opening forces. For this purpose a injector with hydraulic control system, using a liquid under pressure for the opening process was designed. On the basis of air pressure measurements in the flow line after the injector, the analysis of opening and closing of the valve was made. Measurements of outflow mass of the injector were also carried out. The results showed that the designed injector meets the requirements necessary to supply ADCR engine by the CNG fuel.

  2. Safety risk assessment for vertical concrete formwork activities in civil engineering construction.

    Science.gov (United States)

    López-Arquillos, Antonio; Rubio-Romero, Juan Carlos; Gibb, Alistair G F; Gambatese, John A

    2014-01-01

    The construction sector has one of the worst occupational health and safety records in Europe. Of all construction tasks, formwork activities are associated with a high frequency of accidents and injuries. This paper presents an investigation of the activities and related safety risks present in vertical formwork for in-situ concrete construction in the civil engineering sector. Using the methodology of staticized groups, twelve activities and ten safety risks were identified and validated by experts. Every safety risk identified in this manner was quantified for each activity using binary methodology according to the frequency and severity scales developed in prior research. A panel of experts was selected according to the relevant literature on staticized groups. The results obtained show that the activities with the highest risk in vertical formwork tasks are: Plumbing and leveling of forms, cutting of material, handling materials with cranes, and climbing or descending ladders. The most dangerous health and safety risks detected were falls from height, cutting and overexertion. The research findings provide construction practitioners with further evidence of the hazardous activities associated with concrete formwork construction and a starting point for targeting worker health and safety programmes.

  3. Researching wicked problems in a construction project

    DEFF Research Database (Denmark)

    Jacobsen, Peter Holm

    (Lave, 1988) and critical psychology (Axel, 2002; Dreier, 2008; Højholt & Kousholt, 2011). Situated learning theories have developed some valuable methodologies that can be used to study learning as an aspect of social practices and critical psychology have expanded theories of situated learning...... be elaborated more upon (Pink et. al., 2010). Getting access, formulating strategies for analyses, finding concepts and selecting methods such as participant observations and interviews are often problematic aspects, that influences the knowledge that researchers produces in a number of ways that relates...... to empirical research. I will argue that uncertainty is an important aspect of doing empirical research because the empirical research is a part of a situated learning process and that uncertain situations are a central part of conducting empirical research. I will use an example from my study of the early...

  4. Construction of an Engineer's Notebook Rubric

    Science.gov (United States)

    Kelley, Todd R.

    2014-01-01

    It is evident that there is a need for assessment instruments that measure design and engineering design skills, knowledge, and ways of design thinking. These student assessments must be authentic to engineering design practices and measure key elements of the engineering design process. Kelley (2011) presented a rationale to include…

  5. Construction and engineering report for advanced nuclear fuel development facility

    International Nuclear Information System (INIS)

    Cho, S. W.; Park, J. S.; Kwon, S.J.; Lee, K. W.; Kim, I. J.; Yu, C. H.

    2003-09-01

    The design and construction of the fuel technology development facility was aimed to accommodate general nuclear fuel research and development for the HANARO fuel fabrication and advanced fuel researches. 1. Building size and room function 1) Building total area : approx. 3,618m 2 , basement 1st floor, ground 3th floor 2) Room function : basement floor(machine room, electrical room, radioactive waste tank room), 1st floor(research reactor fuel fabrication facility, pyroprocess lab., metal fuel lab., nondestructive lab., pellet processing lab., access control room, sintering lab., etc), 2nd floor(thermal properties measurement lab., pellet characterization lab., powder analysis lab., microstructure analysis lab., etc), 3rd floor(AHU and ACU Room) 2. Special facility equipment 1) Environmental pollution protection equipment : ACU(2sets), 2) Emergency operating system : diesel generator(1set), 3) Nuclear material handle, storage and transport system : overhead crane(3sets), monorail hoist(1set), jib crane(2sets), tank(1set) 4) Air conditioning unit facility : AHU(3sets), packaged air conditioning unit(5sets), 5) Automatic control system and fire protection system : central control equipment(1set), lon device(1set), fire hose cabinet(3sets), fire pump(3sets) etc

  6. Constructive Synergy in Design Science Research: A Comparative Analysis of Design Science Research and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2014-01-01

    Information systems research is focused on creating knowledge which can be applied in organizations. Design science research, which specifically aims at applying existing knowledge to solve interesting and relevant business problems, has been steadily gaining support in information systems research....... However, design science research is not the only design-oriented research framework available. Accordingly, this raises the question of whether there is something to learn between the different approaches. This paper contributes to answering this question by comparing design science research...... with the constructive research approach. The conclusion is that the two approaches are similar and compatible, save for details in practical requirements and partly underlying philosophical assumptions. The main finding that arises from the comparison is, however, that there is a potential problem in claiming knowledge...

  7. Constructive Synergy in Design Science Research: A Comparative Analysis of Design Science Research and the Constructive Research Approach

    DEFF Research Database (Denmark)

    Piirainen, Kalle; Gonzalez, Rafael A.

    2014-01-01

    with the constructive research approach. The conclusion is that the two approaches are similar and compatible, save for details in practical requirements and partly underlying philosophical assumptions. The main finding that arises from the comparison is, however, that there is a potential problem in claiming knowledge......Information systems research is focused on creating knowledge which can be applied in organizations. Design science research, which specifically aims at applying existing knowledge to solve interesting and relevant business problems, has been steadily gaining support in information systems research....... However, design science research is not the only design-oriented research framework available. Accordingly, this raises the question of whether there is something to learn between the different approaches. This paper contributes to answering this question by comparing design science research...

  8. Empirical research on constructing Taiwan's eco- environmental ...

    African Journals Online (AJOL)

    EJIRO

    Analysis of research results brings several important findings. (1) Taiwan's economic ..... above that this study is an innovative expansion and combination of material flow calculation and ..... using thermodynamic approach. Resour. Conserv.

  9. On how to do construction management communications engineering

    Institute of Scientific and Technical Information of China (English)

    Zhang Zhi

    2014-01-01

    In the communication construction projects, improving the efectivenes of project management is an important part of the quality asurance program. The efectivenes of the communication and construction project management is afected by many factors. Therefore, the discusion of communication construction project management efectivenes is good for improving the quality of projects of great significance. This paper analyzes the characteristics and problems of communication construction projects, reflecting the importance of project management; then discused the factors afecting the efectivenes of project management; finaly targeted to improve the communication of construction project management efectivenes propose specific methods to ensure communication quality of construction projects.

  10. Converging clinical and engineering research on neurorehabilitation

    CERN Document Server

    Torricelli, Diego; Pajaro, Marta

    2013-01-01

    Restoring human motor and cognitive function has been a fascinating research area during the last century. Interfacing the human nervous system with electro-mechanical rehabilitation machines is facing its crucial passage from research to clinical practice, enhancing the potentiality of therapists, clinicians and researchers to rehabilitate, diagnose and generate knowledge. The 2012 International Conference on Neurorehabilitation (ICNR2012, www.icnr2012.org) brings together researchers and students from the fields of Clinical Rehabilitation, Applied Neurophysiology and Biomedical Engineering, covering a wide range of research topics:   · Clinical Impact of Technology · Brain-Computer Interface in Rehabilitation · Neuromotor & Neurosensory modeling and processing · Biomechanics in Rehabilitation · Neural Prostheses in Rehabilitation · Neuro-Robotics in Rehabilitation · Neuromodulation   This Proceedings book includes general contributions from oral and poster sessions, as well as from special sess...

  11. The nature of qualitative construction partnering research : literature review

    NARCIS (Netherlands)

    Marieke Venselaar; Hans Warmelink

    2017-01-01

    from the publisher's site: "The purpose of this paper is to investigate the nature of qualitative construction partnering research. Design/methodology/approach. In total, 20 qualitative peer-reviewed papers about construction partnering research are reviewed. Findings: The results show four

  12. Genetically engineered multivalent single chain antibody constructs for cancer therapy

    International Nuclear Information System (INIS)

    Surinder Batra

    2006-01-01

    increase its tumor: normal tissue ratio for improved therapeutic index, we engineered a variety antibody constructs. These constructs were evaluated using novel approaches like special radionuclides, pretargeting and optimization. Due to the smaller size, the engineered antibody molecules should penetrate better throughout a tumor mass, with less dose heterogeneity, than is the case with intact IgG. Multivalent scFvs with an appropriate radionuclide, therefore, hold promising prospects for cancer therapy and clinical imaging in MAb-based radiopharmaceuticals. In addition, the human anti-mouse antibodies (HAMA) responses in patients against antibody-based therapy are usually directed against the immunoglobulin constant regions; however, anti-idiotypic responses can also be detected. The HAMA responses reduce the efficacy of treatment by removing the circulating antibody molecules, fragments, and possibly scFvs by altering the pharmacokinetic properties of the antibody. HAMA responses against divalent IgG, divalent Ig fragments, and possibly multimeric scFvs could cause immune complex formation with hypersensitivity or allergic reactions that could be harmful to patients. The use of small molecules, such as scFvs (monomeric as well as multimeric), with their shorter biological half-lives and the lack of the constant regions and humanized variable (binding regions) performed in our studies should reduce the development of HAMA. The generation of humanized and fully human scFvs should further reduce the development of HAMA. Specific accomplishments on the project are the production of large amounts of recombinant antibodies as they are required in large amounts for cancer diagnosis and therapy. A variety of single-chain Fv (scFv) constructs were engineered for the desired pharmacokinetic properties. Tetrameric and dimeric scFvs showed a two-fold advantage: (1) there was a considerable gain in avidity as compared to smaller fragments, and (2) the biological half-life was more

  13. 48 CFR 952.236 - Construction and architect-engineer contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 952.236 Section 952.236 Federal Acquisition Regulations System DEPARTMENT OF ENERGY... Construction and architect-engineer contracts. ...

  14. 48 CFR 853.236 - Construction and architect-engineer contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Construction and architect-engineer contracts. 853.236 Section 853.236 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS FORMS Prescription of Forms 853.236 Construction and architect-engineer...

  15. Research Labs | College of Engineering & Applied Science

    Science.gov (United States)

    Engineering Multimedia Software Laboratory Computer Science Nanotechnology for Sustainable Energy and Engineering Concentration on Ergonomics M.S. Program in Computer Science Interdisciplinary Concentration on Energy Doctoral Programs in Engineering Non-Degree Candidate Departments Biomedical Engineering

  16. Engineers are from Mars and educators are from Venus: Research ...

    African Journals Online (AJOL)

    ... are from Venus: Research supervision in engineering and educational collaboration. ... The projects usually entailed an interdisciplinary thesis that addressed an ... in chemical engineering, the work-readiness of civil engineering students, ...

  17. Restoration of limited defects of the cartilage with the use of cell-engineered constructs

    Directory of Open Access Journals (Sweden)

    S. A. Gerasimov

    2017-01-01

    Full Text Available Aim: to develop a three-dimensional composite cell-engineered constructs (CEC for restoration of limited defects of the cartilage in experiment.Materials and methods. To create a cell-engineered constructs (CEC, were used collagenic carriers: «Chondro Gide» impermeable bilayer membrane and «Osteoplast» permeable matrix. A comparative study of their cytotoxic and adhesion properties was made in vitro. Chondroplastic potential of prepared CECs based on collagenous matrices with allogeneic mesenchymal stem cells (MSC of the rabbit bone marrow grown on their surface was assessed in vivo. A cylindrical defect of the cartilage of the medial femoral condyle 3.3 mm in diameter at a depth of 1.5 mm was formed on both rabbit feet. Laboratory animals were divided into 3 groups: control group; Experiment 1 group with Chondro Gide used as the MSC carrier within CEC; Experiment 2 group using Osteoplast matrix. Upon experiment completion, a morphometric and histomorphologic research of tissue specimens was made. For statistical evaluation of the results a defect region recovery factor (RF was offered and used. Results. After a 6-month observation period the control group showed partial recovery of the defect region with the recovery factor (RF of 0.62 ± 0.06. The RF in Experiment 1 group equalled to 0.79 ± 0.07, Experiment 2 group revealed RF at the level of 0.88 ± 0.02. Statistical analysis of the research results shows that the use of CEC used in Experiment 2 group reduces a relative risk of therapeutic failures by 92.9%, and absolute risk – by 43.3% as compared to Experiment 1 group. Histomorphologic research data are indicative of a hyaline cartilage formation in the central defect zone, which is partially close to the intact cartilage to the maximum with zonality marked.Conclusion. Results of the research of the developed three-dimension cell-engineered constructs consisting of mesenchymal stem cells of the bone marrow grown on the Osteoplast

  18. 48 CFR 836.209 - Construction contracts with architect-engineer firms.

    Science.gov (United States)

    2010-10-01

    ... with architect-engineer firms. 836.209 Section 836.209 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER...-engineer firms. (a) When the contracting officer considers it necessary or advantageous to award a contract...

  19. Tissue Engineering Organs for Space Biology Research

    Science.gov (United States)

    Vandenburgh, H. H.; Shansky, J.; DelTatto, M.; Lee, P.; Meir, J.

    1999-01-01

    Long-term manned space flight requires a better understanding of skeletal muscle atrophy resulting from microgravity. Atrophy most likely results from changes at both the systemic level (e.g. decreased circulating growth hormone, increased circulating glucocorticoids) and locally (e.g. decreased myofiber resting tension). Differentiated skeletal myofibers in tissue culture have provided a model system over the last decade for gaining a better understanding of the interactions of exogenous growth factors, endogenous growth factors, and muscle fiber tension in regulating protein turnover rates and muscle cell growth. Tissue engineering these cells into three dimensional bioartificial muscle (BAM) constructs has allowed us to extend their use to Space flight studies for the potential future development of countermeasures.

  20. Research Progress of Building Materials Used in Construction Land

    Science.gov (United States)

    Niu, Yan

    2018-01-01

    Construction land preparation is an important aspect of land remediation project. The research of materials in the process of land improvement is the foundation and the core. Therefore, it is necessary to study the materials that may be involved in the process of building land preparation. In this paper, the research on the construction materials such as recycled concrete, geosynthetics, soil stabilizers, soil improvers, building insulation materials and inorganic fibrous insulation materials, which are commonly used in construction sites, is reviewed and discussed in this paper. Land remediation project involved in the construction of land materials to provide reference.

  1. 2nd International Conference on Construction and Building Research

    CERN Document Server

    Fernández-Plazaola, Igor; Hidalgo-Delgado, Francisco; Martínez-Valenzuela, María; Medina-Ramón, Francisco; Oliver-Faubel, Inmaculada; Rodríguez-Abad, Isabel; Salandin, Andrea; Sánchez-Grandia, Rafael; Tort-Ausina, Isabel; Construction and Building Research

    2014-01-01

    Many areas of knowledge converge in the building industry and therefore research in this field necessarily involves an interdisciplinary approach. Effective research requires strong relations between a broad variety of scientific and technological domains and more conventional construction or craft processes, while also considering advanced management processes, where all the main actors permanently interact. This publication takes an interdisciplinary approach grouping various studies on the building industry chosen from among the works presented for the 2nd International Conference on Construction and Building Research. The papers examine aspects of materials and building systems; construction technology; energy and sustainability; construction management; heritage, refurbishment and conservation. The information contained within these pages may be of interest to researchers and practitioners in construction and building activities from the academic sphere, as well as public and private sectors.

  2. ABB.-Combustion Engineering's Experience in Nuclear Power Plant Engineering and Construction in Korea

    International Nuclear Information System (INIS)

    Veris, James W.

    1992-01-01

    The Yonggwang Nuclear Project is a milestone project for the Korean Nuclear Industry. The Project has the two objectives of obtaining self-reliance in all aspects of nuclear technology and of constructing two modern nuclear power plants under the leadership of Korean companies acting as prime contractors. ABB.-Combustion Engineering 1000 MW System 80+ TM was chosen in 1987 as the NSLS design to meet these two objectives. This paper summarizers the significant experiences and lessons learned through the first four years of the Project as well as identifying implications for such future projects. The unique challenges of the project are identified and an evaluation of the experiences in the technology, self-reliance program and in the design and manufacturing processes will be made

  3. Research and development of construction at high temperature

    International Nuclear Information System (INIS)

    Hayashi, Shigeru

    1974-01-01

    The contents and present situation of the researches on the construction of a multipurpose high temperature gas reactor are reported. The researches have been divided into five research blocks. The first block deals with the development of analytical codes required for the evaluation of construction in accordance with MITI Notification No.501, ASME section III, and case interpretation 1331-4-8. The codes for the analysis of two dimensional construction named FINEHEAT, AXINCRE and DYNSHL, those for three dimensional construction named STEREO and PINOSE, and for aseismatic analysis DYNAP were completed. The second block deals with the method for evaluating high temperature construction in accordance with ASME section III, case interpretation 133-5-8 and the evaluation of analytical codes. This block is related to a new technological field including a variety of unsolved problems. The third block deals with basic performance data on construction materials used at high temperature. There is very few basic data concerning material performance. The heretofore reported data are confirmed to enable the evaluation of construction. The fourth block deals with the application of construction evaluation method. The object of this block is to grasp the behavior of stress by experimental means, and to enable evaluation and to simultaneously establish stress index. The fifth block deals with the research for the determination of construction, including measuring technique, the effect of radiation heat on heat transfer efficiency, the prevention of metallic adhesion and the welding performance of seven materials by TIC, electron beam and plasma welding. (Iwakiri, K.)

  4. 3D engineered models for highway construction : the Iowa experience.

    Science.gov (United States)

    2015-06-01

    3D engineered modeling is a relatively new and developing technology that can provide numerous bene ts to owners, engineers, : contractors, and the general public. This manual is for highway agencies that are considering or are in the process of s...

  5. The Role of Hypothesis in Constructive Design Research

    DEFF Research Database (Denmark)

    Bang, Anne Louise; Krogh, Peter; Ludvigsen, Martin

    2012-01-01

    and solid perspective on how to keep constructive design research on track, this paper offers a model for understanding the role of hypothesis in constructive design research. The model allows for understanding the hypothesis’s relation to research motivation, questions, experiments, evaluation...... and knowledge production. The intention of the model is to have it serve as a tool in the research process aiding the researcher to understand at what “level” discussions and claims are brought forward, and what consequences these might have for the research work at hand. Thus, the paper claims the central...

  6. NATO Advanced Research Workshop on Molecular Engineering for Advanced Materials

    CERN Document Server

    Schaumburg, Kjeld

    1995-01-01

    An important aspect of molecular engineering is the `property directed' synthesis of large molecules and molecular assemblies. Synthetic expertise has advanced to a state which allows the assembly of supramolecules containing thousands of atoms using a `construction kit' of molecular building blocks. Expansion in the field is driven by the appearance of new building blocks and by an improved understanding of the rules for joining them in the design of nanometer-sized devices. Another aspect is the transition from supramolecules to materials. At present no single molecule (however large) has been demonstrated to function as a device, but this appears to be only a matter of time. In all of this research, which has a strongly multidisciplinary character, both existing and yet to be developed analytical techniques are and will remain indispensable. All this and more is discussed in Molecular Engineering for Advanced Materials, which provides a masterly and up to date summary of one of the most challenging researc...

  7. Off reactor testings. Technological engineering applicative research

    International Nuclear Information System (INIS)

    Doca, Cezar

    2001-01-01

    By the end of year 2000 over 400 nuclear electro-power units were operating world wide, summing up a 350,000 MW total capacity, with a total production of 2,300 TWh, representing 16% of the world's electricity production. Other 36 units, totalizing 28,000 MW, were in construction, while a manifest orientation towards nuclear power development was observed in principal Asian countries like China, India, Japan and Korea. In the same world's trend one find also Romania, the Cernavoda NPP Unit 1 generating electrical energy into the national system beginning with 2 December 1996. Recently, the commercial contract was completed for finishing the Cernavoda NPP Unit 2 and launching it into operation by the end of year 2004. An important role in developing the activity of research and technological engineering, as technical support for manufacturing the CANDU type nuclear fuel and supplying with equipment the Cernavoda units, was played by the Division 7 TAR of the INR Pitesti. Qualification testings were conducted for: - off-reactor CANDU type nuclear fuel; - FARE tools, pressure regulators, explosion proof panels; channel shutting, as well as functional testing for spare pushing facility as a first step in the frame of the qualification tests for the charging/discharging machine (MID) 4 and 5 endings. Testing facilities are described, as well as high pressure hot/cool loops, measuring chains, all of them fulfilling the requirements of quality assurance. The nuclear fuel off-reactor tests were carried out to determine: strength; endurance; impact, pressure fall and wear resistance. For Cernavoda NPP equipment testings were carried out for: the explosion proof panels, pressure regulators, behaviour to vibration and wear of the steam generation tubings, effects of vibration upon different electronic component, channel shutting (for Cernavoda Unit 2), MID operating at 300 and 500 cycles. A number of R and D programs were conducted in the frame of division 7 TAR of INR

  8. Summaries of FY 1997 engineering research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    This report documents the Basic Energy Sciences (BES) Engineering Research Program for fiscal year 1997, it provides a summary for each of the program projects in addition to a brief program overview. The report is intended to provide staff of Congressional committees, other executive departments, and other DOE offices with substantive program information so as to facilitate governmental overview and coordination of Federal research programs. Of equal importance, its availability facilitates communication of program information to interested research engineers and scientists. The individual project summaries follow the program overview. The summaries are ordered alphabetically by name of institution; the table of contents lists all the institutions at which projects were sponsored in fiscal year 1997. Each project entry begins with an institutional-departmental heading. The names of investigators are listed immediately below the title. The funding level for fiscal year 1997 appears to the right of address. The summary description of the project completes the entry. A separate index of Principal Investigators includes phone number, fax number and e-main address, where available.

  9. Present status of high temperature engineering test and research, 1994

    International Nuclear Information System (INIS)

    1994-10-01

    High temperature gas-cooled reactors have excellent features such as the generation of high temperature close to 1000degC, very high inherent safety and high fuel burnup. By the advanced basic research under high temperature irradiation condition, the creation of various new technologies which become the momentum of future technical innovation can be expected. The construction of the high temperature engineering test reactor (HTTR) was decided in 1987, which aims at the thermal output of 30 MW and the coolant temperature at reactor exit of 950degC. The initial criticality is scheduled in 1998. Japan Atomic Energy Research Institute has advanced the high temperature engineering test and research, and plans the safety verifying test of the HTTR, the test of connecting heat utilization plants and so on. In this report, mainly the results obtained for one year from May, 1993 are summarized. The outline of the high temperature engineering test and development of the HTTR technologies are reported. (K.I.)

  10. A data-driven approach to reverse engineering customer engagement models: towards functional constructs.

    Directory of Open Access Journals (Sweden)

    Natalie Jane de Vries

    Full Text Available Online consumer behavior in general and online customer engagement with brands in particular, has become a major focus of research activity fuelled by the exponential increase of interactive functions of the internet and social media platforms and applications. Current research in this area is mostly hypothesis-driven and much debate about the concept of Customer Engagement and its related constructs remains existent in the literature. In this paper, we aim to propose a novel methodology for reverse engineering a consumer behavior model for online customer engagement, based on a computational and data-driven perspective. This methodology could be generalized and prove useful for future research in the fields of consumer behaviors using questionnaire data or studies investigating other types of human behaviors. The method we propose contains five main stages; symbolic regression analysis, graph building, community detection, evaluation of results and finally, investigation of directed cycles and common feedback loops. The 'communities' of questionnaire items that emerge from our community detection method form possible 'functional constructs' inferred from data rather than assumed from literature and theory. Our results show consistent partitioning of questionnaire items into such 'functional constructs' suggesting the method proposed here could be adopted as a new data-driven way of human behavior modeling.

  11. A data-driven approach to reverse engineering customer engagement models: towards functional constructs.

    Science.gov (United States)

    de Vries, Natalie Jane; Carlson, Jamie; Moscato, Pablo

    2014-01-01

    Online consumer behavior in general and online customer engagement with brands in particular, has become a major focus of research activity fuelled by the exponential increase of interactive functions of the internet and social media platforms and applications. Current research in this area is mostly hypothesis-driven and much debate about the concept of Customer Engagement and its related constructs remains existent in the literature. In this paper, we aim to propose a novel methodology for reverse engineering a consumer behavior model for online customer engagement, based on a computational and data-driven perspective. This methodology could be generalized and prove useful for future research in the fields of consumer behaviors using questionnaire data or studies investigating other types of human behaviors. The method we propose contains five main stages; symbolic regression analysis, graph building, community detection, evaluation of results and finally, investigation of directed cycles and common feedback loops. The 'communities' of questionnaire items that emerge from our community detection method form possible 'functional constructs' inferred from data rather than assumed from literature and theory. Our results show consistent partitioning of questionnaire items into such 'functional constructs' suggesting the method proposed here could be adopted as a new data-driven way of human behavior modeling.

  12. Screening candidate systems engineers: a research design

    CSIR Research Space (South Africa)

    Goncalves, DP

    2009-07-01

    Full Text Available engineering screening methodology that could be used to screen potential systems engineers. According to their design, this can be achieved by defining a system engineering profile according to specific psychological attributes, and using this profile...

  13. Implementation of critical success factors in construction research ...

    African Journals Online (AJOL)

    Construction research and development (R&D) process has a number of issues that affect its success. These issues imply that Critical Success Factors (CSFs) of construction R&D process are not properly addressed. Not knowing CSFs could lead to not implementing them and not paying proper attention for them. The study ...

  14. Collaborative Engineering for Research and Development

    Science.gov (United States)

    Davis, Jose M.; Keys, L. Ken; Chen, Injazz J.

    2004-01-01

    Research and development (R&D) organizations are being required to be relevant, to be more application-oriented, and to be partners in the strategic management of the business while meeting the same challenges as the rest of the organization, namely: (1) reduced time to market; (2) reduced cost; (3) improved quality; (4) increased reliability; and (5) increased focus on customer needs. Recent advances in computer technology and the Internet have created a new paradigm of collaborative engineering or collaborative product development (CPD), from which new types of relationships among researchers and their partners have emerged. Research into the applicability and benefits of CPD in a low/no production, R&D, and/or government environment is limited. In addition, the supply chain management (SCM) aspects of these relationships have not been studied. This paper presents research conducted at the NASA Glenn Research Center (GRC) investigating the applicability of CPD and SCM in an R&D organization. The study concentrates on the management and implementation of space research activities at GRC. Results indicate that although the organization is engaged in collaborative relationships that incorporate aspects of SCM, a number of areas, such as development of trust and information sharing merit special attention.

  15. Construction informatics - Issues in engineering, computer science and ontology

    DEFF Research Database (Denmark)

    Eir, Asger

    2004-01-01

    and conceptual modelling of civil engineering and design. Due to the interdisciplinary content, the first half of the study has been carried out at Department of Civil Engineering (BYG"DTU), The Technical University of Denmark; whereas the second half has been carried out at Informatics and Mathematical....... With origin in civil engineering and design issues, the study was directed towards computer science oriented theories in an attempt to introduce such theories in modelling and clarification of the domain. This strategy turned out to be a strength for the study and this thesis. However, it also discovered some...... problems in carrying out such a truly interdisciplinary Ph.D. study. Per Galle s and Dines Bjørner's common background in computer science has been essential for the success of this study. The original title of the Ph.D. project was Design and application of a civil engineering ontology. However, it became...

  16. Nuclear engineering aspects of glioma BNCT research in Italy

    International Nuclear Information System (INIS)

    Curzio, G.; Mazzini, M.

    1998-01-01

    A research project on Boron Neutron Capture Therapy (BNCZ) of gliomas has been set up in Italy, with the participation of Departments of Oncology and Mechanical and Nuclear Construction (DCMN) of the University of Pisa, as well as the Neuroscience and Physics Departments of the Universities of Roma. The specific objective of DCMN Research Unit is the study of the physical-engineering aspects related to BNCT. The paper outlines the research lines in progress at DCMN: Monte Carlo calculations of neutron dose distribution for BNCT treatment planning; measurements of neutron fluxes, spectra and doses by neutron detectors specifically set up; design of modifications to the nuclear reactors of ENEA Casaccia Center. In particular, the paper emphasizes the most original contributions on dosimetric aspects, both from informatic and experimental points of view.(author)

  17. 77 FR 14462 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2012-03-09

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development....S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development.... Name: Research, Engineering & Development Advisory Committee. Time and Date: April 18, 2012--9:30 a.m...

  18. 78 FR 47049 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2013-08-02

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development...; 5 U.S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and.... Name: Research, Engineering & Development Advisory Committee. Time and Date: September 18--8:30 a.m. to...

  19. 77 FR 54648 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2012-09-05

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development....S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development...: Research, Engineering & Development Advisory Committee. TIME AND DATE: September 26, 2012--9 a.m. to 4 p.m...

  20. 76 FR 12404 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2011-03-07

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development....S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development...: Research, Engineering & Development Advisory Committee. Time and Date: April 20, 2011--9:30 a.m. to 4 p.m...

  1. 75 FR 14243 - Research, Engineering And Development Advisory Committee

    Science.gov (United States)

    2010-03-24

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering And Development....S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development...: Research, Engineering & Development Advisory Committee. Time and Date: April 21, 2010--9 a.m. to 5 p.m...

  2. 76 FR 44648 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2011-07-26

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development....S.C. App. 2), notice is hereby given of a meeting of the FAA Research, Engineering and Development.... Name: Research, Engineering & Development Advisory Committee. Time and Date: September 21, 2011--9 a.m...

  3. 78 FR 16357 - Research, Engineering and Development Advisory Committee

    Science.gov (United States)

    2013-03-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Research, Engineering and Development... hereby given of a meeting of the FAA Research, Engineering and Development (R,E&D) Advisory Committee. Name: Research, Engineering & Development Advisory Committee. Time and Date: April 24--8:30 a.m. to 4...

  4. The preliminary research for biosynthetic engineering by radiation fusion technology

    Energy Technology Data Exchange (ETDEWEB)

    Roh, Chang Hyun; Jung, U Hee; Park, Hae Ran [KAERI, Daejeon (Korea, Republic of)

    2012-01-15

    The purpose of this project is to elucidate the solution to the production of bioactive substance using biotransformation process from core technology of biosynthetic engineering by radiation fusion technology. And, this strategy will provide core technology for development of drugs as new concept and category. Research scopes and contents of project include 1) The development of mutant for biosynthetic engineering by radiation fusion technology 2) The development of host for biosynthetic engineering by radiation fusion technology 3) The preliminary study for biosynthetic engineering of isoflavone by radiation fusion technology. The results are as follows. Isoflavone compounds(daidzein, hydroxylated isoflavone) were analyzed by GC-MS. The study of radiation doses and p-NCA high-throughput screening for mutant development were elucidated. And, it was carried out the study of radiation doses for host development. Furthermore, the study of redox partner and construction of recombinant strain for region-specific hydroxylation(P450, redox partner). In addition, the biological effect of 6,7,4'-trihydroxyisoflavone as an anti-obesity agent was elucidated in this study.

  5. Research and development in power plant engineering

    International Nuclear Information System (INIS)

    Riedle, K.; Taud, R.

    2001-01-01

    Research and development are a bridge for visions that are escorted to a successful market introduction. Also in power plant engineering, research and development are a lever with which the product power plant, its technology and processes can be adapted to the quickly changing future market. In the overview given by this paper, therefore at first the development boosters and targets are outlined from the viewpoint of the market; then the available technology portfolio is addressed in a concise way. Targets for the development can be seen from the support programmes of the governments. Before a preview is given, some development topics from the point of view of the manufacturer are introduced. (orig.) [de

  6. The NIOSH Construction Program: research to practice, impact, and developing a National Construction Agenda.

    Science.gov (United States)

    Gillen, Matt

    2010-06-01

    The U.S. National Institute for Occupational Safety and Health (NIOSH) conducts research to improve and protect the health and safety of workers. This paper describes the experience of the NIOSH Construction Program with two recent program planning initiatives intended to improve the program: (a) an independent external review of work over the past decade and (b) the development of strategic goals organized into a "National Construction Agenda" to guide a decade of future work. These goals, developed with input from construction industry stakeholders and researchers, are a part of the NIOSH National Occupational Research Agenda (NORA) initiative. The NORA goals are intended to provide an ambitious set of goals for all construction stakeholders to work together on. Both efforts relate to insuring the relevance and impact of research, reflecting an emerging policy perspective that research programs should be judged not just by the quality and quantity of science produced, but by the industry impact and tangible benefit resulting from the research. This paper describes how views on research planning have evolved to incorporate lessons learned about how research leads to improved safety and health for workers. It also describes the process used to develop the goals and the resulting strategic and intermediate goals that comprise the National Construction Agenda. (c) 2010 Elsevier Ltd. All rights reserved.

  7. A Systems Engineering Framework for Design, Construction and Operation of the Next Generation Nuclear Plant

    International Nuclear Information System (INIS)

    Edward J. Gorski; Charles V. Park; Finis H. Southworth

    2004-01-01

    Not since the International Space Station has a project of such wide participation been proposed for the United States. Ten countries, the European Union, universities, Department of Energy (DOE) laboratories, and industry will participate in the research and development, design, construction and/or operation of the fourth generation of nuclear power plants with a demonstration reactor to be built at a DOE site and operational by the middle of the next decade. This reactor will be like no other. The Next Generation Nuclear Plant (NGNP) will be passively safe, economical, highly efficient, modular, proliferation resistant, and sustainable. In addition to electrical generation, the NGNP will demonstrate efficient and cost effective generation of hydrogen to support the President's Hydrogen Initiative. To effectively manage this multi-organizational and technologically complex project, systems engineering techniques and processes will be used extensively to ensure delivery of the final product. The technological and organizational challenges are complex. Research and development activities are required, material standards require development, hydrogen production, storage and infrastructure requirements are not well developed, and the Nuclear Regulatory Commission may further define risk-informed/performance-based approach to licensing. Detailed design and development will be challenged by the vast cultural and institutional differences across the participants. Systems engineering processes must bring the technological and organizational complexity together to ensure successful product delivery. This paper will define the framework for application of systems engineering to this $1.5B - $1.9B project

  8. Life-cycle environmental performance of renewable building materials in the context of residential construction : phase II research report : an extension to the 2005 phase I research report. Module N, Life-cycle inventory of manufacturing prefinished engineered wood flooring in the eastern United States

    Science.gov (United States)

    Richard D. Bergman; Scott A. Bowe

    2011-01-01

    This study summarizes the environmental performance of prefinished engineered wood flooring using life-cycle inventory (LCI) analysis. Using primary mill data gathered from manufacturers in the eastern United States and applying the methods found in Consortium for Research on Renewable Industrial Materials (CORRIM) Research Guidelines and International Organization of...

  9. Constructs and methods for genome editing and genetic engineering of fungi and protists

    Science.gov (United States)

    Hittinger, Christopher Todd; Alexander, William Gerald

    2018-01-30

    Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.

  10. Construction of a bibliographic information database and a web directory for the nuclear science and engineering

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jeong Hoon; Kim, Tae Whan; Lee, Ji Ho; Chun, Young Chun; Yu, An Na

    2005-11-15

    The objective of this project is to construct the bibliographic information database and the web directory in the nuclear field. Its construction is very timely and important. Because nuclear science and technology has an considerable effect all over the other sciences and technologies due to its property of giant and complex engineering. We aimed to firmly build up a basis of efficient management of the bibliographic information database and the web directory in the nuclear field. The results of this project that we achieved in this year are as follows : first, construction of the bibliographic information database in the nuclear field(the target title: 1,500 titles ; research report: 1,000 titles, full-text report: 250 titles, full-text article: 250 titles). Second, completion of construction of the web directory in the nuclear field by using SWING (the total figure achieved : 2,613 titles). We plan that we will positively give more information to the general public interested in the nuclear field and to the experts of the field through this bibliographic information database on KAERI's home page, KAERI's electronic library and other related sites as well as participation at various seminars and meetings related to the nuclear field.

  11. A review of factors influencing underground construction quality and the performance of engineered features

    International Nuclear Information System (INIS)

    Talbot, R.; Moy, D.; Breeds, C.D.; Kostelec, C.M.; Emsley, S.J.; Shuttle, D.; Cutler, J.; Hedman, T.; Carlsson, A.

    1992-01-01

    This report describes research to identify and rank the factors that should be considered for an assessment of the radioactive containment capability of repository engineered features. Containment is to be achieved through the use of multiple barriers to radionuclide movement, including the waste, waste container, repository structures and backfill, and repository seals. A review of the literature is used to identify radionuclide mobilisation and transport processes for the anticipated environmental conditions, and to compile a data base of repository design features, functional requirements, and design objectives. For selected design components, the report identifies alternative designs and factors contributing to design, focusing on the requirements for a design process, design specifications, construction requirements, and quality assurance requirements for the both design and construction. Existing practice in large, underground civil construction projects is used as a part of comparison, in conjunction with reported performance assessments, to determine those areas in which the repository developer will need to provide additional data, justification, and documentation prior to construction to ensure that performance requirements can be achieved. (Author)

  12. Engineering and Design. Design, Construction, and Maintenance of Relief Wells

    National Research Council Canada - National Science Library

    1992-01-01

    The objective of this manual is to provide guidance and information on the design, construction, and maintenance of pressure relief wells installed for the purpose of relieving subsurface hydrostatic...

  13. Computational model-informed design and bioprinting of cell-patterned constructs for bone tissue engineering.

    Science.gov (United States)

    Carlier, Aurélie; Skvortsov, Gözde Akdeniz; Hafezi, Forough; Ferraris, Eleonora; Patterson, Jennifer; Koç, Bahattin; Van Oosterwyck, Hans

    2016-05-17

    Three-dimensional (3D) bioprinting is a rapidly advancing tissue engineering technology that holds great promise for the regeneration of several tissues, including bone. However, to generate a successful 3D bone tissue engineering construct, additional complexities should be taken into account such as nutrient and oxygen delivery, which is often insufficient after implantation in large bone defects. We propose that a well-designed tissue engineering construct, that is, an implant with a specific spatial pattern of cells in a matrix, will improve the healing outcome. By using a computational model of bone regeneration we show that particular cell patterns in tissue engineering constructs are able to enhance bone regeneration compared to uniform ones. We successfully bioprinted one of the most promising cell-gradient patterns by using cell-laden hydrogels with varying cell densities and observed a high cell viability for three days following the bioprinting process. In summary, we present a novel strategy for the biofabrication of bone tissue engineering constructs by designing cell-gradient patterns based on a computational model of bone regeneration, and successfully bioprinting the chosen design. This integrated approach may increase the success rate of implanted tissue engineering constructs for critical size bone defects and also can find a wider application in the biofabrication of other types of tissue engineering constructs.

  14. Computer aided construction engineering system for nuclear power plants

    International Nuclear Information System (INIS)

    Yoshinaga, Toshiaki; Nakajima, Akira; Miyahara, Ryohei; Miura, Jun

    1990-01-01

    The construction CAE system for nuclear power plants is the tool for the construction work simulator (procedure, processes and management simulation) connected to 3D-CAD (three-dimensional plant layout planning CAD). The data used for construction work simulation are registered in the data base as the installation smallest unit data from the 3D-CAD. This construction work simulator comprises the automatic installation procedure decision system, with which a construction planner decides installation procedure by using a high performance graphic work station, and based on a 3D-CAD model, utilizing empirical procedure logic, the dialogue system for making the installation procedure more optimal by utilizing effectively the graphic function, the evaluation system for synthetically evaluating workability, personnel plan and so on by adding the simulation of human behavior based on these procedures, the schedule system which carries out work process simulation based on the above, the data base system for letting to do these plans effectively and the project management system. By means of these, the plant construction of high quality is expected. (K.I.)

  15. Construction of ion accelerator for ion-surface interaction research

    International Nuclear Information System (INIS)

    Obara, Kenziro; Ohtsuka, Hidewo; Yamada, Rayji; Abe, Tetsuya; Sone, Kazuho

    1977-09-01

    A Cockcroft-Walton type ion accelerator for ion-surface interaction research was installed at Plasma Engineering Laboratory, Division of Thermonuclear Fusion Research, JAERI, in March 1977. Its maximum accelerating voltage is 400 kV. The accelerator has some outstanding features compared with the conventional type. Described are setup of the accelerator specification of the major components, safety system and performance. (auth.)

  16. Emerging Biofabrication Strategies for Engineering Complex Tissue Constructs

    DEFF Research Database (Denmark)

    Pedde, R. Daniel; Mirani, Bahram; Navaei, Ali

    2017-01-01

    , outlines the use of common biomaterials and advanced hybrid scaffolds, and describes several design considerations including the structural, physical, biological, and economical parameters that are crucial for the fabrication of functional, complex, engineered tissues. Finally, the applications...... of these biofabrication strategies in neural, skin, connective, and muscle tissue engineering are explored.......The demand for organ transplantation and repair, coupled with a shortage of available donors, poses an urgent clinical need for the development of innovative treatment strategies for long-term repair and regeneration of injured or diseased tissues and organs. Bioengineering organs, by growing...

  17. Discursive Constructions of Design and Implications for Engineering Education

    DEFF Research Database (Denmark)

    Petersen, Rikke Premer

    Recognition of design discourses at play in professional practice is key when discussing ways to reintroduce designerly ways in engineering education. This paper outlines three design discourses discussed in literature and mirroring contemporary design practice: Viewing ‘design as art’ upholds...... on the discourses discussed, three key elements of design are highlighted: the materiality, the social, and the reflective sides of designing. All of these elements are represented in the issues of communication, which can be a central focus area when taking a designerly turn in engineering practice....

  18. An overview of the NASA rotary engine research program

    Science.gov (United States)

    Meng, P. R.; Hady, W. F.

    1984-01-01

    A brief overview and technical highlights of the research efforts and studies on rotary engines over the last several years at the NASA Lewis Research Center are presented. The test results obtained from turbocharged rotary engines and preliminary results from a high performance single rotor engine were discussed. Combustion modeling studies of the rotary engine and the use of a Laser Doppler Velocimeter to confirm the studies were examined. An in-house program in which a turbocharged rotary engine was installed in a Cessna Skymaster for ground test studies was reviewed. Details are presented on single rotor stratified charge rotary engine research efforts, both in-house and on contract.

  19. Researchers, other experts examine climate engineering issues

    International Nuclear Information System (INIS)

    Baum, R.

    1994-01-01

    The feasibility of deliberately engineering Earth's climate--and the social, economic, political, and ethical issues raised by such projects--were explored by two panels at the annual meeting of the American Association for the Advancement of Science (AAAS), held in late February in San Francisco. These projects include dispersal of sulfate particles in the stratosphere to reflect sunlight, fertilizing the southern oceans with iron to stimulate phytoplankton growth, and injecting ethane or propane into the stratosphere over Antarctica to counteract ozone-depleting chemical reactions. The feasibility of such projects was the focus of the first panel. Joyce E. Penner, of Lawrence Livermore National Laboratory, describes studies of natural and anthropogenic sulfate aerosols that suggest that these chemical species reduce the solar flux reaching the Earth's surface. The research indicates it might be possible to counteract greenhouse warming, at least in part, by injecting sulfate aerosols into the stratosphere. Should such an approach be used to counteract greenhouse warming? Should any climate engineering project be considered? These sorts of questions were the focus of the second panel

  20. Statistical Engineering in Air Traffic Management Research

    Science.gov (United States)

    Wilson, Sara R.

    2015-01-01

    NASA is working to develop an integrated set of advanced technologies to enable efficient arrival operations in high-density terminal airspace for the Next Generation Air Transportation System. This integrated arrival solution is being validated and verified in laboratories and transitioned to a field prototype for an operational demonstration at a major U.S. airport. Within NASA, this is a collaborative effort between Ames and Langley Research Centers involving a multi-year iterative experimentation process. Designing and analyzing a series of sequential batch computer simulations and human-in-the-loop experiments across multiple facilities and simulation environments involves a number of statistical challenges. Experiments conducted in separate laboratories typically have different limitations and constraints, and can take different approaches with respect to the fundamental principles of statistical design of experiments. This often makes it difficult to compare results from multiple experiments and incorporate findings into the next experiment in the series. A statistical engineering approach is being employed within this project to support risk-informed decision making and maximize the knowledge gained within the available resources. This presentation describes a statistical engineering case study from NASA, highlights statistical challenges, and discusses areas where existing statistical methodology is adapted and extended.

  1. Armstrong Flight Research Center Research Technology and Engineering Report 2015

    Science.gov (United States)

    Voracek, David F.

    2016-01-01

    I am honored to endorse the 2015 Neil A. Armstrong Flight Research Center’s Research, Technology, and Engineering Report. The talented researchers, engineers, and scientists at Armstrong are continuing a long, rich legacy of creating innovative approaches to solving some of the difficult problems and challenges facing NASA and the aerospace community.Projects at NASA Armstrong advance technologies that will improve aerodynamic efficiency, increase fuel economy, reduce emissions and aircraft noise, and enable the integration of unmanned aircraft into the national airspace. The work represented in this report highlights the Center’s agility to develop technologies supporting each of NASA’s core missions and, more importantly, technologies that are preparing us for the future of aviation and space exploration.We are excited about our role in NASA’s mission to develop transformative aviation capabilities and open new markets for industry. One of our key strengths is the ability to rapidly move emerging techniques and technologies into flight evaluation so that we can quickly identify their strengths, shortcomings, and potential applications.This report presents a brief summary of the technology work of the Center. It also contains contact information for the associated technologists responsible for the work. Don’t hesitate to contact them for more information or for collaboration ideas.

  2. Sustainable Construction Supply Chains through Synchronized Production Planning and Control in Engineer-to-Order Enterprises

    Directory of Open Access Journals (Sweden)

    Patrick Dallasega

    2017-10-01

    Full Text Available Sustainability in the supply chain is becoming more and more important for industrial enterprises in different sectors. This research article focuses on construction supply chains (CSCs in the Engineer-to-Order (ETO industry, where every product is almost unique based on specific customer needs and requirements. The development of methods and approaches for more sustainable supply chain management in construction is becoming even more important. Engineering, fabrication of parts and their installation on-site are not always well synchronized in ETO supply chains. The results of such supply chains are long lead times, inefficient material transport and high and uncontrolled levels of work-in-progress (WIP. This article describes a conceptual approach to synchronize demand on-site with supply in manufacturing using the CONstant Work In Progress (ConWIP concept from Lean Management to achieve Just-in-Time (JIT supply. As a result, sustainable supply chains in ETO enterprises, with optimizations from an economic, ecological and social point of view, can be designed. The approach has been validated in an industrial case study.

  3. Measurement plan and observational construction program on drift excavation at the Horonobe Underground Research Laboratory project

    International Nuclear Information System (INIS)

    Yamasaki, Masanao; Yamaguchi, Takehiro; Funaki, Hironori; Fujikawa, Daisuke; Tsusaka, Kimikazu

    2008-09-01

    The Horonobe URL Project is being pursued by the Japan Atomic Energy Agency (JAEA) to enhance the reliability of relevant disposal technologies through investigations of the deep geological environment within the host sedimentary formations at Horonobe, northern Hokkaido. The project consists of two major research areas, 'Geoscientific Research' and 'R and D' on Geological Disposal', and proceeds in three overlapping phases, 'Phase I: Surface-based investigation', 'Phase II: Construction' and 'Phase III: Operation', over a period of 20 years. On the Horonobe URL Project, 'Phase 1' was finished in 2005FY and construction of the underground facility was started since then. Now, 'Phase 2' (investigations during construction of the underground facilities) is on-going. On the 'Development of engineering techniques for use in the deep underground environment' in Phase 1, based on the various types of data acquired on investigations from the surface, the design of underground facility in advance was planned. At the inception of the Phase II investigations, an investigation report titled 'Measurement Plan and Observational Construction Program on Shaft Excavation at the Horonobe URL Project' (hereinafter referred to as 'Observational Construction Program') was published. The Observational Construction Program summarizes followings from the Phase I investigations: measurements for safety/reasonable construction, measurements for R and D on enhancement of shaft design/construction technology, and measurements for verification of the deep geological environment model estimated before shaft excavation, and it is on-going. This report summarizes the measurement plan during construction of drifts based on the design in advance and the observational construction program for feedback measurements data into design and construction on subsequent steps. This report also describes about design and construction management program of underground facility and R and D program on

  4. Annual cooperative research report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This is FY 1995 annual report of research results of the Yayoi research group and the high speed neutron science group as well as the cooperative application research results of reactor `Yayoi` application, related to reactor `Yayoi` and of accelerator Linac. The reactor was also operated smoothly in FY 1995, and its application and related research reached to 25 themes. The research using Linac reduced apparently to 7 themes from 14 in FY 1994, which showed apparent reduction because of integration of the cooperative research theme but showed more results in general. in particular, it was a wonderful result to success the formation of sub-pico second pulsed beam in world wide area. The Yayoi research group reported 13 researches which was two more than these in last fiscal year, all of which were the most advanced discussions in the field related to nuclear engineering. The high speed neutron science group started in FY 1993 aiming at construction of new research field on application of the high speed neutron as a quantum beam with excellent nuclear transfer and transmittance, to manifestation and control of new material function and design and creation of intelligent material. In FY 1995, the group began his full scale operation and reported on 8 themes. (G.K.)

  5. Annual cooperative research report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1995

    International Nuclear Information System (INIS)

    1996-01-01

    This is FY 1995 annual report of research results of the Yayoi research group and the high speed neutron science group as well as the cooperative application research results of reactor 'Yayoi' application, related to reactor 'Yayoi' and of accelerator Linac. The reactor was also operated smoothly in FY 1995, and its application and related research reached to 25 themes. The research using Linac reduced apparently to 7 themes from 14 in FY 1994, which showed apparent reduction because of integration of the cooperative research theme but showed more results in general. in particular, it was a wonderful result to success the formation of sub-pico second pulsed beam in world wide area. The Yayoi research group reported 13 researches which was two more than these in last fiscal year, all of which were the most advanced discussions in the field related to nuclear engineering. The high speed neutron science group started in FY 1993 aiming at construction of new research field on application of the high speed neutron as a quantum beam with excellent nuclear transfer and transmittance, to manifestation and control of new material function and design and creation of intelligent material. In FY 1995, the group began his full scale operation and reported on 8 themes. (G.K.)

  6. Problematising the `Career Academic' in UK construction and engineering education: does the system want what the system gets?

    Science.gov (United States)

    Pilcher, Nick; Forster, Alan; Tennant, Stuart; Murray, Mike; Craig, Nigel

    2017-11-01

    'Career Academics' are principally research-led, entering academia with limited or no industrial or practical experience. UK Higher Education Institutions welcome them for their potential to attain research grant funding and publish world-leading journal papers, ultimately enhancing institutional reputation. This polemical paper problematises the Career Academic around three areas: their institutional appeal; their impact on the student experience, team dynamics and broader academic functions; and current strategic policy to employ them. We also argue that recent UK Government teaching-focused initiatives will not address needs to employ practical academics, or 'Pracademics' in predominantly vocational Construction and Engineering Education. We generate questions for policy-makers, institutions and those implementing strategy. We argue that research is key, but partial rebalancing will achieve a diverse academic skill base to achieve contextualised construction and engineering education. In wider European contexts, the paper resonates with issues of academic 'drift' and provides reflection for others on the UK context.

  7. Global Journal of Engineering Research - Vol 14, No 1 (2015)

    African Journals Online (AJOL)

    Compressive and flexural strength of cement mortar stabilized with raffia palm fruit ... Effect of compactive effort on strength indices of laterite treated with calcium ... Engineering properties of scoria concrete as a construction material · EMAIL ...

  8. Engineering properties of scoria concrete as a construction material ...

    African Journals Online (AJOL)

    The weight and cost of plain concrete are part of the setbacks in its use for construction purposes especially in low-cost housing delivery. This paper reports the experimental results of samples of concrete produced from a mix combination of cement, fine aggregate (sand) and volcanic scoria as coarse aggregate. The scoria ...

  9. A constructivist approach for teaching research methodology in construction management

    NARCIS (Netherlands)

    Hartmann, Andreas; Doree, Andries G.; Martin, Ludwig

    2010-01-01

    Construction Management (CM) is an acknowledged field of expertise and profession that requires students to research real world problems. To prepare the students for this task, many CM programs contain a Research Methodology (RM) course. However, after taking part in these courses, many students

  10. Design Guide for Selection and Specification of Kevlar Rope for Ocean Engineering and Construction.

    Science.gov (United States)

    1976-07-01

    public rtoieco cnd sol . It i Idim .buttm Is ul"rnimi.. OCEAN ENGINEERING AND CONSTRUCTION PROJECT OFFICE CHESAPEAKE DIVISION NAVAL FACILITIES ENGINEERING...be to have no more than one layer. This is impractical for oceano - graphic purposes. Assuming a need to spooi many layers of rope under tension

  11. STUDY OF ELABORATION OF CONSTRUCTION CRANKSHAFT PISTON OF AUTOMOBILE PNEUMATIC ENGINE

    Directory of Open Access Journals (Sweden)

    Voronkov, А.

    2013-01-01

    Full Text Available Expound are the results of study of elaration of construction of crankshaft 4-cylinder V-evocative piston pneumatic engine, which is made by conversion of serial internal-combustion engine 4Ч 7,6x6,6.

  12. Research on a Scania 11 liter ethanol fueled bus engine

    Energy Technology Data Exchange (ETDEWEB)

    Egebaeck, K E; Pettersson, E

    1996-05-01

    This report presents research carried out on an alcohol fueled bus engine. The engine used was a six cylinder 11 liter compression ignition turbo-charged engine with an inter cooler. The research program included studies of the impact on the emissions when changing different engine components and different settings of the engine. A study of the impact on the engine performance and emissions when using different fuel compositions was also carried out. During the course of the work, the engine was equipped with oxidation catalysts of two different types, one of which was more efficient than the other concerning the oxidation of unburnt fuel related components. One of the main purposes of the research was to improve the emission characteristics of the engine by an optimization of the engine and its setting. The exhaust emissions were thoroughly characterized with respect to both regulated and unregulated emissions. 13 refs, figs, tabs

  13. Important statistics on engineering and construction of nuclear power plants

    International Nuclear Information System (INIS)

    Budwani, R.N.

    1976-01-01

    During the past seven years, a study was made of the engineering and craft manpower/manhour requirements, craft breakdowns by totals and peaks, material requirements, unit man-hours, rate of manhour/capital expenditures, and schedule requirements of representative nuclear power plants across the United States. The study is based on information received from electric utilities, engineer-constructors, site visits, the Nuclear Regulatory Commission (NRC), personal contacts, and the exchange of information with knowledgeable people. Preliminary data in the form of tables and figures are presented. Factors which have and will influence manpower, manhours, material requirements, building volumes, and schedules are outlined, and a list of recommendations is presented. The objective of this study has been to show in a concise fashion what the trend has been and what may be anticipated for future nuclear power plants

  14. Security Research on Engineering Database System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Engine engineering database system is an oriented C AD applied database management system that has the capability managing distributed data. The paper discusses the security issue of the engine engineering database management system (EDBMS). Through studying and analyzing the database security, to draw a series of securi ty rules, which reach B1, level security standard. Which includes discretionary access control (DAC), mandatory access control (MAC) and audit. The EDBMS implem ents functions of DAC, ...

  15. Proposal for the increase of the contract amounts for LHC civil engineering construction and civil engineering consultancy contracts

    CERN Document Server

    2001-01-01

    This document concerns the increase of the contract amounts for LHC civil engineering construction contracts and civil engineering consultancy contracts. The Finance Committee is invited to agree to the increase of the contract amounts with: - the joint venture TEERAG-ASDAG (AT), C. BARESEL (DE) and LOCHER (CH) for civil engineering construction, package 1, for a revised total amount of 91 500 000 Swiss francs, subject to revision; - the joint venture EDF (FR) and KNIGHT&PIESOLD (GB) for the provision of civil engineering consultancy services, package 1, for a revised total amount of 14 400 000 Swiss francs, subject to revision; - the joint venture TAYLOR WOODROW (GB), AMEC (GB) and SPIE BATIGNOLLES (FR) for civil engineering construction, package 3a, for a revised total amount of 118 000 000 Swiss francs, subject to revision; - the joint venture BROWN&ROOT (GB), INTECSA (ES) and HIDROTECNICA (PT) for the provision of civil engineering consultancy services, package 3, for a revised total amount of 14 ...

  16. UPS fellowships support creative engineering research

    OpenAIRE

    Crumbley, Liz

    2007-01-01

    A new $40,000 grant marks the 11th anniversary of support from the United Parcel Service (UPS) Foundation for doctoral fellowships in the Human Factors and Safety Engineering Graduate Program in the Grado Department of Industrial and Systems Engineering (ISE) in the College of Engineering.

  17. Human subject research for engineers a practical guide

    CERN Document Server

    de Winter, Joost C F

    2017-01-01

    This Brief introduces engineers to the main principles in ethics, research design, statistics, and publishing of human subject research. In recent years, engineering has become strongly connected to disciplines such as biology, medicine, and psychology. Often, engineers (and engineering students) are expected to perform human subject research. Typical human subject research topics conducted by engineers include human-computer interaction (e.g., evaluating the usability of software), exoskeletons, virtual reality, teleoperation, modelling of human behaviour and decision making (often within the framework of ‘big data’ research), product evaluation, biometrics, behavioural tracking (e.g., of work and travel patterns, or mobile phone use), transport and planning (e.g., an analysis of flows or safety issues), etc. Thus, it can be said that knowledge on how to do human subject research is indispensable for a substantial portion of engineers. Engineers are generally well trained in calculus and mechanics, but m...

  18. Research on Channel Strategies of Modern Agricultural Engineering Demonstration Sites in Guangzhou

    OpenAIRE

    Wen-guang Liang; Chun Xie; Qian-qian Pang

    2015-01-01

    The research discusses the channel structure of modern agricultural engineering demonstration sites in Guangzhou. It analyzes the strategies of channel competition, personnel combination, transportation combination and terminal network construction. Enterprises adapt different marketing channel strategies on the basis of the type of the market. The research has made certain achievement and has certain guiding significance.

  19. Engineering Research Division publication report, calendar year 1980

    International Nuclear Information System (INIS)

    Miller, E.K.; Livingston, P.L.; Rae, D.C.

    1980-06-01

    Each year the Engineering Research Division of the Electronics Engineering Department at Lawrence Livermore Laboratory has issued an internal report listing all formal publications produced by the Division during the calendar year. Abstracts of 1980 reports are presented

  20. Engineering Research Division report on reports: calendar year 1979

    International Nuclear Information System (INIS)

    Gardner, C.L.; Johnston, S.J.

    1980-03-01

    A bibliography of publications of members of the Engineering Research Division of the Electronics Engineering Department is presented for 1979. Abstracts for 148 publications are included, along with author and keywork indexes

  1. The Role of the Military Construction Engineers in the Hybrid War

    Science.gov (United States)

    2015-06-12

    an increase in the need for infrastructure. Military construction engineers were responsible for the NIKE construction program, storage sites for...has minimized the significance of geographical and political boundaries. Because of these facts, the NATO Bi-Strategic Command has assessed Hybrid

  2. Analogy and construction of meaning in science teaching physics for engineering students

    Directory of Open Access Journals (Sweden)

    Thamara FAGÚNDEZ ZAMBRANO

    2011-12-01

    Full Text Available Normal 0 21 false false false ES X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} An analogy can be interpreted as a structured mapping between two domains, one called domain-domain and another named source-goal. This is one of functions can play an analogy, and this function we are interested in this work to analyze how specific an analogy involved in construction and justification of new knowledge. The research finds about the use of analogies as a teaching resource are three teachers experienced in college physics classes. More specifically on the role of that resource in the construction of scientific knowledge and its contribution the teaching and learning of college-level physics and general training of the engineering student. The context of the study is Faculty of Engineering, University of Carabobo, Venezuela. The approach methodology is qualitative. This is a descriptive-interpretative cases study.  Analysis and results to identify and classify analogies by use given by teachers and their contribution to the construction of meaning scientists. Implications for improving teaching practice are extracted

  3. Causes of delays on Construction Projects in Kuwait according to opinion of engineers working in Kuwait

    OpenAIRE

    Naser S. Almutairi

    2016-01-01

    This paper presents an investigation into analysis of the causes of delays on Construction Projects in Kuwait according to opinion of engineers working in Kuwait. This is achieved through identification of the major causes of delays in the construction industry as reported in literature and using a questionnaire survey to collect the views of the various key players in the Kuwaiti construction industry. The data is analyzed and the views of the groups surveyed discussed and the relative impor...

  4. A puzzle assembly strategy for fabrication of large engineered cartilage tissue constructs.

    Science.gov (United States)

    Nover, Adam B; Jones, Brian K; Yu, William T; Donovan, Daniel S; Podolnick, Jeremy D; Cook, James L; Ateshian, Gerard A; Hung, Clark T

    2016-03-21

    Engineering of large articular cartilage tissue constructs remains a challenge as tissue growth is limited by nutrient diffusion. Here, a novel strategy is investigated, generating large constructs through the assembly of individually cultured, interlocking, smaller puzzle-shaped subunits. These constructs can be engineered consistently with more desirable mechanical and biochemical properties than larger constructs (~4-fold greater Young׳s modulus). A failure testing technique was developed to evaluate the physiologic functionality of constructs, which were cultured as individual subunits for 28 days, then assembled and cultured for an additional 21-35 days. Assembled puzzle constructs withstood large deformations (40-50% compressive strain) prior to failure. Their ability to withstand physiologic loads may be enhanced by increases in subunit strength and assembled culture time. A nude mouse model was utilized to show biocompatibility and fusion of assembled puzzle pieces in vivo. Overall, the technique offers a novel, effective approach to scaling up engineered tissues and may be combined with other techniques and/or applied to the engineering of other tissues. Future studies will aim to optimize this system in an effort to engineer and integrate robust subunits to fill large defects. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Engineering research and development for the Elise Heavy Ion Induction Accelerator

    International Nuclear Information System (INIS)

    Reginato, L.; Peters, C.

    1995-08-01

    The Fusion Energy Research engineering team has been conducting Research and Development Associated with the Construction (RDAC) of the Elise accelerator since the approval of Key Decision one (KD1 is start of construction). The engineering design effort has worked in close cooperation with the physics design staff to achieve all parameters of the Elise accelerator. The design included the 2 MV injector, matching section, combiner, induction cells, electric/magnetic quadrupoles, alignment system and controls. All major designs and some hardware testing will be discussed

  6. Engineering research and development for the Elise heavy ion induction accelerator

    International Nuclear Information System (INIS)

    Reginato, L.; Peters, C.

    1996-01-01

    The fusion energy research engineering team has been conducting research and development associated with the construction of the Elise accelerator since the approval of key decision 1 (this is the start of construction). The engineering design effort has worked in close cooperation with the physics design staff to achieve all parameters of the Elise accelerator. The design included the 2 MV injector, matching section, combiner, induction cells, electric-magnetic quadrupoles, alignment system and controls. All major designs and some hardware testing will be discussed. (orig.)

  7. Constructing an Efficient Self-Tuning Aircraft Engine Model for Control and Health Management Applications

    Science.gov (United States)

    Armstrong, Jeffrey B.; Simon, Donald L.

    2012-01-01

    Self-tuning aircraft engine models can be applied for control and health management applications. The self-tuning feature of these models minimizes the mismatch between any given engine and the underlying engineering model describing an engine family. This paper provides details of the construction of a self-tuning engine model centered on a piecewise linear Kalman filter design. Starting from a nonlinear transient aerothermal model, a piecewise linear representation is first extracted. The linearization procedure creates a database of trim vectors and state-space matrices that are subsequently scheduled for interpolation based on engine operating point. A series of steady-state Kalman gains can next be constructed from a reduced-order form of the piecewise linear model. Reduction of the piecewise linear model to an observable dimension with respect to available sensed engine measurements can be achieved using either a subset or an optimal linear combination of "health" parameters, which describe engine performance. The resulting piecewise linear Kalman filter is then implemented for faster-than-real-time processing of sensed engine measurements, generating outputs appropriate for trending engine performance, estimating both measured and unmeasured parameters for control purposes, and performing on-board gas-path fault diagnostics. Computational efficiency is achieved by designing multidimensional interpolation algorithms that exploit the shared scheduling of multiple trim vectors and system matrices. An example application illustrates the accuracy of a self-tuning piecewise linear Kalman filter model when applied to a nonlinear turbofan engine simulation. Additional discussions focus on the issue of transient response accuracy and the advantages of a piecewise linear Kalman filter in the context of validation and verification. The techniques described provide a framework for constructing efficient self-tuning aircraft engine models from complex nonlinear

  8. Update on Engine Combustion Research at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Jay Keller; Gurpreet Singh

    2001-01-01

    The objectives of this paper are to describe the research efforts in diesel engine combustion at Sandia National Laboratories' Combustion Research Facility and to provide recent experimental results. We have four diesel engine experiments supported by the Department of Energy, Office of Heavy Vehicle Technologies: a one-cylinder version of a Cummins heavy-duty engine, a diesel simulation facility, a one-cylinder Caterpillar engine to evaluate combustion of alternative fuels, and a homogeneous-charge, compression ignition (HCCI) engine. Recent experimental results of diesel combustion research will be discussed and a description will be given of our HCCI experimental program and of our HCCI modeling work

  9. Research on Chinese Intelligent Guanglianda in High-rise Construction

    Directory of Open Access Journals (Sweden)

    Romanovich Marina

    2018-01-01

    Full Text Available Since the reform and opening up in China, the rapid development of China's construction industry, especially after 2011, BIM technology in China has a rapid development and depth of application. This article mainly discusses the process of development of China's construction industry management and the process of development of BIM technology in China and, the use of software in China, the main use of revit in 3D modeling (design stage, the use of Guanglianda in the whole process of construction management. This article researches on Guanglianda and the applications were described, for example, in the integrated project of management information, labor management information, construction video surveillance, material management, material site acceptance. This paper also elaborates on the cooperation of Revit and Guanglianda in different stages. This paper also elaborates on a construction case in China, and makes a description of the problems of crane, facts and time, and then explores the reasons behind the rapid construction of China. And the feasibility of China's construction management approach to the introduction of Russia.

  10. Research on Chinese Intelligent Guanglianda in High-rise Construction

    Science.gov (United States)

    Romanovich, Marina; Shi, Peiyu; Wang, Ziyue; Zhao, Liang; Gerasimova, Vera

    2018-03-01

    Since the reform and opening up in China, the rapid development of China's construction industry, especially after 2011, BIM technology in China has a rapid development and depth of application. This article mainly discusses the process of development of China's construction industry management and the process of development of BIM technology in China and, the use of software in China, the main use of revit in 3D modeling (design stage), the use of Guanglianda in the whole process of construction management. This article researches on Guanglianda and the applications were described, for example, in the integrated project of management information, labor management information, construction video surveillance, material management, material site acceptance. This paper also elaborates on the cooperation of Revit and Guanglianda in different stages. This paper also elaborates on a construction case in China, and makes a description of the problems of crane, facts and time, and then explores the reasons behind the rapid construction of China. And the feasibility of China's construction management approach to the introduction of Russia.

  11. A Critical Review of the Use of Virtual Reality in Construction Engineering Education and Training.

    Science.gov (United States)

    Wang, Peng; Wu, Peng; Wang, Jun; Chi, Hung-Lin; Wang, Xiangyu

    2018-06-08

    Virtual Reality (VR) has been rapidly recognized and implemented in construction engineering education and training (CEET) in recent years due to its benefits of providing an engaging and immersive environment. The objective of this review is to critically collect and analyze the VR applications in CEET, aiming at all VR-related journal papers published from 1997 to 2017. The review follows a three-stage analysis on VR technologies, applications and future directions through a systematic analysis. It is found that the VR technologies adopted for CEET evolve over time, from desktop-based VR, immersive VR, 3D game-based VR, to Building Information Modelling (BIM)-enabled VR. A sibling technology, Augmented Reality (AR), for CEET adoptions has also emerged in recent years. These technologies have been applied in architecture and design visualization, construction health and safety training, equipment and operational task training, as well as structural analysis. Future research directions, including the integration of VR with emerging education paradigms and visualization technologies, have also been provided. The findings are useful for both researchers and educators to usefully integrate VR in their education and training programs to improve the training performance.

  12. Annual report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1995

    International Nuclear Information System (INIS)

    1996-08-01

    This is an annual report prepared on research education action, operation state of research instruments and others in FY 1995 at Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo. The laboratory has four large instruments such as high speed neutron source reactor, 'Yayoi', electron linac, fundamentally experimental equipment for blanket design of nuclear fusion reactor, and heavy radiation research equipment (HIT), of which former two are used for cooperative research with universities in Japan, and the next blanket and the last HIT are also presented for cooperative researches in Faculty of Engineering and in University of Tokyo, respectively. FY 1995 was the beginning year of earnest discussion on future planning of this facility with concentrated effort. These four large research instruments are all in their active use. And, their further improvement is under preparation. In this report, the progress in FY 1995 on operation and management of the four large instruments are described at first, and on next, research actions, contents of theses for degree and graduation of students as well as research results of laboratory stuffs are summarized. These researches are constituted mainly using these large instruments in the facility, aiming at development of advanced and new field of atomic energy engineering and relates to nuclear reactor first wall engineering, nuclear reactor fuel cycle engineering, electromagnetic structure engineering, thermal-liquid engineering, mathematical information engineering, quantum beam engineering, new type reactor design and so on. (G.K.)

  13. Annual report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    This is an annual report prepared on research education action, operation state of research instruments and others in FY 1995 at Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo. The laboratory has four large instruments such as high speed neutron source reactor, `Yayoi`, electron linac, fundamentally experimental equipment for blanket design of nuclear fusion reactor, and heavy radiation research equipment (HIT), of which former two are used for cooperative research with universities in Japan, and the next blanket and the last HIT are also presented for cooperative researches in Faculty of Engineering and in University of Tokyo, respectively. FY 1995 was the beginning year of earnest discussion on future planning of this facility with concentrated effort. These four large research instruments are all in their active use. And, their further improvement is under preparation. In this report, the progress in FY 1995 on operation and management of the four large instruments are described at first, and on next, research actions, contents of theses for degree and graduation of students as well as research results of laboratory stuffs are summarized. These researches are constituted mainly using these large instruments in the facility, aiming at development of advanced and new field of atomic energy engineering and relates to nuclear reactor first wall engineering, nuclear reactor fuel cycle engineering, electromagnetic structure engineering, thermal-liquid engineering, mathematical information engineering, quantum beam engineering, new type reactor design and so on. (G.K.)

  14. Engineering Cardiac Muscle Tissue: A Maturating Field of Research.

    Science.gov (United States)

    Weinberger, Florian; Mannhardt, Ingra; Eschenhagen, Thomas

    2017-04-28

    Twenty years after the initial description of a tissue engineered construct, 3-dimensional human cardiac tissues of different kinds are now generated routinely in many laboratories. Advances in stem cell biology and engineering allow for the generation of constructs that come close to recapitulating the complex structure of heart muscle and might, therefore, be amenable to industrial (eg, drug screening) and clinical (eg, cardiac repair) applications. Whether the more physiological structure of 3-dimensional constructs provides a relevant advantage over standard 2-dimensional cell culture has yet to be shown in head-to-head-comparisons. The present article gives an overview on current strategies of cardiac tissue engineering with a focus on different hydrogel methods and discusses perspectives and challenges for necessary steps toward the real-life application of cardiac tissue engineering for disease modeling, drug development, and cardiac repair. © 2017 American Heart Association, Inc.

  15. Engaged scholarship in construction management research: the adoption of information and communications technology in construction projects

    NARCIS (Netherlands)

    Voordijk, Johannes T.; Adriaanse, Adriaan Maria

    2016-01-01

    The objective is to explore what engaged scholarship (ES) could mean for construction management research in facilitating interactions between practice and theory. ES aims to develop knowledge that advances both science and practice through engagement of scholars with practice. Three types of ES are

  16. The Stirling engine. Simply explained, easily constructed. 9. rev. and enl. ed.; Der Stirlingmotor. Einfach erklaert und leicht gebaut

    Energy Technology Data Exchange (ETDEWEB)

    Viebach, Dieter

    2010-07-01

    Subsequently to a easily comprehensively description of the function and characteristics of Stirling engines, the author of the book under consideration describes the construction of a model Stirling engine on the basis of clear construction drawings. A delicacy for experienced modelers: The 'amazing model', a miniature Stirling engine consisting of beverage cans, has been running with the warmth of the human hand. Even in this technically demanding model, the construction will be described accurately by detailed construction drawings.

  17. Optimization of In-Cylinder Pressure Filter for Engine Research

    Science.gov (United States)

    2017-06-01

    ARL-TR-8034 ● JUN 2017 US Army Research Laboratory Optimization of In-Cylinder Pressure Filter for Engine Research by Kenneth...Laboratory Optimization of In-Cylinder Pressure Filter for Engine Research by Kenneth S Kim, Michael T Szedlmayer, Kurt M Kruger, and Chol-Bum M...

  18. The Atlantic rift in Engineering Education Research Methodology

    DEFF Research Database (Denmark)

    de Graaff, Erik

    2015-01-01

    engineering. A revival of engineering education research started in the USA around the turn of the century. Building on the concept of ‘scholarship of teaching’, engineers were challenged to investigate their own role as educators. Since these researchers have their academic background mostly in engineering......In Europe educational research branched off from social sciences during the sixties of the last century. Combining theories and methods from pedagogy, sociology and psychology researchers explored the different fields of education, ranging from kindergarten till higher education including...... and science, they tend to aim for ‘rigorous research’ according to the natural sciences. Worldwide the engineering education community has recognized the need to blend both the social sciences research approach and rigorous research. This paper explores the variation in research methods used by researchers...

  19. Engineering Research, Development and Technology, FY95: Thrust area report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the knowledge base, process technologies, specialized equipment, tools and facilities to support current and future LLNL programs. Engineering`s efforts are guided by a strategy that results in dual benefit: first, in support of Department of Energy missions, such as national security through nuclear deterrence; and second, in enhancing the nation`s economic competitiveness through their collaboration with US industry in pursuit of the most cost-effective engineering solutions to LLNL programs. To accomplish this mission, the Engineering Research, Development, and Technology Program has two important goals: (1) identify key technologies relevant to LLNL programs where they can establish unique competencies, and (2) conduct high-quality research and development to enhance their capabilities and establish themselves as the world leaders in these technologies. To focus Engineering`s efforts, technology thrust areas are identified and technical leaders are selected for each area. The thrust areas are comprised of integrated engineering activities, staffed by personnel from the nine electronics and mechanical engineering divisions, and from other LLNL organizations. This annual report, organized by thrust area, describes Engineering`s activities for fiscal year 1995. The report provides timely summaries of objectives methods, and key results from eight thrust areas: computational electronics and electromagnetics; computational mechanics; microtechnology; manufacturing technology; materials science and engineering; power conversion technologies; nondestructive evaluation; and information engineering.

  20. Experimental research on the Stirling engine

    Science.gov (United States)

    Ishizaki, Y.; Tani, Y.; Haramura, N.

    1982-01-01

    Experiments on Stirling engines of the 50 KW class were conducted to clarify the characteristics of the engine and its problems. The problems involve durability of the high temperature heat exchanger which is exposed to high flame temperatures above 1600 C, thermal distortion and high temperature corrosion of the devices near combustion, and of the preheater.

  1. Process Systems Engineering Education: Learning by Research

    Science.gov (United States)

    Abbas, A.; Alhammadi, H. Y.; Romagnoli, J. A.

    2009-01-01

    In this paper, we discuss our approach in teaching the final-year course Process Systems Engineering. Students are given ownership of the course by transferring to them the responsibility of learning. A project-based group environment stimulates learning while solving a real engineering problem. We discuss postgraduate student involvement and how…

  2. Journal of Civil Engineering Research and Practice

    African Journals Online (AJOL)

    CMAC-engine”, a blended scheme of Ant Colony Optimization (ACO) and Cost Minimization (CM) algorithms. The feasibility of CMAC-engine is numerically experimented by solving a standard 25-bar space truss in the field of structural engineering ...

  3. Construction of a Solid State Research Facility, Building 3150

    International Nuclear Information System (INIS)

    1993-07-01

    The Department of Energy (DOE) proposes to construct a new facility to house the Materials Synthesis Group (MSG) and the Semiconductor Physics Group (SPG) of the Solid State Division, Oak Ridge National Laboratory (ORNL). The location of the proposed action is Roane County, Tennessee. MSG is involved in the study of crystal growth and the preparation and characterization of advanced materials, such as high-temperature superconductors, while SPG is involved in semiconductor physics research. All MSG and a major pardon of SPG research activities are now conducted in Building 2000, a deteriorating structure constructed in the 1940. The physical deterioration of the roof; the heating, ventilation, and air conditioning (HVAC) system; and the plumbing make this building inadequate for supporting research activities. The proposed project is needed to provide laboratory and office space for MSG and SPG and to ensure that research activities can continue without interruption due to deficiencies in the building and its associated utility systems

  4. The Use of Web Search Engines in Information Science Research.

    Science.gov (United States)

    Bar-Ilan, Judit

    2004-01-01

    Reviews the literature on the use of Web search engines in information science research, including: ways users interact with Web search engines; social aspects of searching; structure and dynamic nature of the Web; link analysis; other bibliometric applications; characterizing information on the Web; search engine evaluation and improvement; and…

  5. Engineer Research and Development Center's Materials Testing Center (MTC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Engineer Research and Development Center's Materials Testing Center (MTC) is committed to quality testing and inspection services that are delivered on time and...

  6. Data-driven engineering design research: Opportunities using open data

    DEFF Research Database (Denmark)

    Parraguez Ruiz, Pedro; Maier, Anja

    2017-01-01

    the already available and continuously growing body of open data sources to create opportunities for research in Engineering Design. Insights are illustrated by an examination of two examples: a study of open source software repositories and an analysis of open business registries in the cleantech industry....... We conclude with a discussion about the limitations, challenges and risks of using open data in Engineering Design research and practice.......Engineering Design research relies on quantitative and qualitative data to describe design-related phenomena and prescribe improvements for design practice. Given data availability, privacy requirements and other constraints, most empirical data used in Engineering Design research can be described...

  7. Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials

    National Research Council Canada - National Science Library

    Alderson, Norris; Alexander, Catherine; Merzbacher, Celia; Chernicoff, William; Middendorf, Paul; Beck, Nancy; Chow, Flora; Poster, Dianne; Danello, Mary Ann; Barrera, Enriqueta

    2006-01-01

    ...) research and information needs related to understanding and management of potential risks of engineered nanoscale materials that may be used, for example, in commercial or consumer products, medical...

  8. UI researchers celebrate latest milestone in construction of atom smasher

    CERN Multimedia

    2007-01-01

    University of Iowa researchers joined their U.S. and international colleagues Dec. 19 in celebrating a major construction mile-stone that brings them one step closer to the completion of the most powerful device ever designed to search for the basic build-ing blocks of matter.

  9. UI researchers celebrate latest milestone in construction of atom smasher

    CERN Multimedia

    2007-01-01

    "University of Iowa researchers joined their U.S. and international colleagues De. 19 in celebrating a major construction mile-stone that brings them one step closer to the completion of the most powerful device ever designed to search for the basic build-ing blocks of matter." (1/2 page)

  10. Engineering education research in European Journal of Engineering Education and Journal of Engineering Education: citation and reference discipline analysis

    Science.gov (United States)

    Wankat, Phillip C.; Williams, Bill; Neto, Pedro

    2014-01-01

    The authors, citations and content of European Journal of Engineering Education (EJEE) and Journal of Engineering Education (JEE) in 1973 (JEE, 1975 EJEE), 1983, 1993, 2003, and available 2013 issues were analysed. Both journals transitioned from house organs to become engineering education research (EER) journals, although JEE transitioned first. In this process the number of citations rose, particularly of education and psychology sources; the percentage of research articles increased markedly as did the number of reference disciplines. The number of papers per issue, the number of single author papers, and the citations of science and engineering sources decreased. EJEE has a very broad geographic spread of authors while JEE authors are mainly US based. A 'silo' mentality where general engineering education researchers do not communicate with EER researchers in different engineering disciplines is evident. There is some danger that EER may develop into a silo that does not communicate with technically oriented engineering professors.

  11. Constructing a research network: accounting knowledge in production

    OpenAIRE

    Joannides , Vassili; Berland , Nicolas

    2013-01-01

    Avec Nicolas Berland; International audience; Purpose - This paper contributes to the sociology-of-science type of accounting literature, addressing how accounting knowledge is established, advanced and extended. Design/methodology/approach - The research question is answered through the example of research into linkages between accounting and religion. Adopting an Actor-Network Theory (ANT) approach, we follow the actors involved in the construction of accounting as an academic discipline th...

  12. Design of rapid hardening engineered cementitious composites for sustainable construction

    Directory of Open Access Journals (Sweden)

    Marushchak Uliana

    2017-12-01

    Full Text Available This paper deals with design of environmentally friendly Rapid Hardening Engineered Cementitious Composite (RHECC nanomodified with ultrafine mineral additives, polycarboxylate ether based superplasticizer, calcium hydrosilicate nanoparticles and dispersal reinforced by fibers. The incremental coefficient of surface activity was proposed in order to estimation of ultrafine supplementary materials (fly ash, methakaolin, microsilica efficiency. A characterization of RHECC’s compressive and flexural properties at different ages is reported in this paper. Early compressive strength of ECC is 45-50 MPa, standard strength – 84-95 MPa and parameter Rc2/Rc28 – 65–70%. The microstructure of the cement matrix and RHECC was investigated. The use of ultrafine mineral supplementary materials provides reinforcement of structure on micro- and nanoscale level (cementing matrix due to formation of sub-microreinforcing hydrate phase as AFt- and C-S-H phases in unclinker part of cement matrix, resulting in the phenomena of “self-reinforcement” on the microstructure level. Designed RHECC may be regarded as lower brittle since the crack resistance coefficient is higher comparison to conventional fine grain concrete.

  13. Design of rapid hardening engineered cementitious composites for sustainable construction

    Science.gov (United States)

    Marushchak, Uliana; Sanytsky, Myroslav; Sydor, Nazar

    2017-12-01

    This paper deals with design of environmentally friendly Rapid Hardening Engineered Cementitious Composite (RHECC) nanomodified with ultrafine mineral additives, polycarboxylate ether based superplasticizer, calcium hydrosilicate nanoparticles and dispersal reinforced by fibers. The incremental coefficient of surface activity was proposed in order to estimation of ultrafine supplementary materials (fly ash, methakaolin, microsilica) efficiency. A characterization of RHECC's compressive and flexural properties at different ages is reported in this paper. Early compressive strength of ECC is 45-50 MPa, standard strength - 84-95 MPa and parameter Rc2/Rc28 - 65-70%. The microstructure of the cement matrix and RHECC was investigated. The use of ultrafine mineral supplementary materials provides reinforcement of structure on micro- and nanoscale level (cementing matrix) due to formation of sub-microreinforcing hydrate phase as AFt- and C-S-H phases in unclinker part of cement matrix, resulting in the phenomena of "self-reinforcement" on the microstructure level. Designed RHECC may be regarded as lower brittle since the crack resistance coefficient is higher comparison to conventional fine grain concrete.

  14. The structure and emerging trends of construction safety management research: a bibliometric review.

    Science.gov (United States)

    Liang, Huakang; Zhang, Shoujian; Su, Yikun

    2018-03-29

    Recently, construction safety management (CSM) practices and systems have become important topics for stakeholders to take care of human resources. However, few studies have attempted to map the global research on CSM. A comprehensive bibliometric review was conducted in this study based on multiple methods. In total, 1172 CSM-related papers from the Web of Science Core Collection database were examined. The analyses focused on publication year, country-institute, publication source, author and research topics. The results indicated that the USA, China, Australia and the UK took leading positions in CSM research. Two branches of journals were identified, namely the branch of engineering science and that of safety science and social science. Additionally, seven themes together with 28 specific topics were detected to allow researchers to track the main structure and temporal evolution of CSM research. Finally, the main research trends and potential research directions were discussed to guide the future research.

  15. Construction of a bibliographic information database for the Nuclear Science and Engineering (IX)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Whan; Oh, Jeong Hun; Choi, Kwang; Keum, Jong Yong [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-12-01

    The major goal of this project is to construct a database in nuclear science and engineering information materials, support the R and D activities of users in this field, finally to support KRISTAL(Korea Research Information for Science and Technology Access Line)'s DB through the KREONet(Korea Research Environment Open Network), as one of the five national information networks. The contents of this project are as follows: 1) Materials selection and collection, 2) Indexing and abstract preparation, 3) Data input and transmission, and 4) document delivery service. In this seventh year, 40,000 records, as total of inputted data, are added to the existing SATURN DB. These records are covered with the articles of nuclear-related core journals, proceedings, seminars, and research reports, etc. And using the Web, this project was important for users to get their needed information itself and to receive the materials of online requested information. And then it will give the chance users not only to promote the the effectiveness of R and D activities, but also to obviate the duplicated research works. 1 fig., 1 tab. (Author)

  16. Construction of a bibliographic information database for the nuclear science and engineering (VIII)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Whan; Kim, Soon Ja; Kim, Young Min; Oh, Jeong Hun; Choi, Kwang [Korea Atomic Energy Research Institute, Taejon (Korea)

    1998-12-01

    The major goal of this project is to construct a database in nuclear science and engineering information materials, support the R and D activities of users in this field, finally to support KRISTAL(Korea Research Information for Science ad Technology Access Line)'s BD through the KREONet (Korea Research Environment Open Network), as one of the five national information networks. The contents of this project are as follows : 1) Materials selection and collection, 2) Indexing and abstract preparation, 3) Data input and transmission, and 4) document delivery service. In this seventh year, 35,000 record as total of inputted data, are added to the existing SATURN DB using the input system. These records are covered with the articles of nuclear-related core journals, proceedings, seminars, and research reports, etc. And using the Web, this project was important for users to get their needed information itself and to receive the materials of online requested information. And then it will give the chance users not only to promote the effectiveness of R and D activities, but also to obviate the duplicated research works. 1 tab. (Author)

  17. Construction of a bibliographic information database for the nuclear science and engineering

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Whan; Kim, Soon Ja; Choi, Kwang [Korea Atomic Energy Reasech Institute, Taejon (Korea)

    1997-12-01

    The major goal of this project is to construct a database in nuclear science and engineering information materials, support the R and D activities of users in this field, finally to support KRISTAL(Korea Research Information for Science and Technology Access Line)'s DB through the KREONet(Korea Research Environment Open Network), as one of the five national information networks. The contents of this project are as follows: (1) Materials selection and collection, (2) Indexing and abstract preparation, (3) Data input and transmission, and (4) document delivery service. In this seventh year, 45000 records, as total of inputted data, are added to the existing SATURN DB. These records are covered with the articles of nuclear-related core journals, proceedings, seminars, and research reports, etc. And using the Web, this project was important for users to get their needed information itself and to receive the materials of online requested information. And then it will give the chance users not only to promote the effectiveness of R and D activities, but also to obviate the duplicated research works. (author). 1 fig., 1 tab.

  18. Construction of a bibliographic information database for the nuclear science and engineering (X)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Whan; Lee, Ji Ho; Oh, Jeong Hun; Choi, Kwang; Chun, Young Chun; Yoo, Jae Bok; Yu, Anna [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-12-01

    The major goal of this project is to construct a database in nuclear science and engineering information materials, support the R and D activities of users in this field, finally to support KRISTAL(Korea Research Information for Science and Technology Access Line)'s DB through the KREONet(Korea Research Environment Open Network), as one of the five national information networks.The contents of this project are as follows: 1) Materials selection and collection, 2) Indexing and abstract preparation, 3) Data input and transmission, and 4) document delivery service. In this Tenth year, 30,500 records ,as total of inputted data, are added to the existing SATURN DB. These records are covered with the articles of nuclear-related core journals, proceedings, seminars, and research reports, etc. And using the Web, this project was important for users to get their needed information itself and to receive the materials of online requested information . And then it will give the chance users not only to promote the effectiveness of R and D activities, but also to obviate the duplicated research works. 2 tabs. (Author)

  19. International Conference on Research and Innovations in Mechanical Engineering

    CERN Document Server

    Singh, Paramjit; Singh, Harwinder; Brar, Gurinder

    2014-01-01

    This book comprises the proceedings of International Conference on Research and Innovations in Mechanical Engineering (ICRIME 2013) organized by Guru Nanak Dev Engineering College, Ludhiana with support from AICTE, TEQIP, DST and PTU, Jalandhar. This international conference served as a premier forum for communication of new advances and research results in the fields of mechanical engineering. The proceedings reflect the conference’s emphasis on strong methodological approaches and focus on applications within the domain of mechanical engineering. The contents of this volume aim to highlight new theoretical and experimental findings in the fields of mechanical engineering and closely related fields, including interdisciplinary fields such as robotics and mechatronics.

  20. Engineering Hyporheic Zones to Attenuate Heavy Metals in Constructed Urban Streams: Performance Data from Constructed Stream Flumes

    Science.gov (United States)

    Halpin, B. N.; Portmann, A. C.; Herzog, S.; Higgins, C.; McCray, J. E.

    2017-12-01

    Urban stormwater runoff is a major cause of water quality impairment along ocean shorelines and in rivers, lakes and estuaries across the United States. In addition to pathogens, nutrients, and organic contaminants, a variety of heavy metals are commonly found at elevated concentrations in urban runoff. Although such metals occur in both dissolved and particulate-bound phases, conventional stormwater controls are typically designed to remove suspended solids, while dissolved phase contaminants remain largely untreated. To address this gap in available stormwater controls, a novel technology, termed Biohydrochemical Enhancements for Streamwater Treatment (BEST), has been developed based on inspiration from the natural hyporheic zone (HZ). BEST utilizes a series of alternating streambed permeabilities to drive efficient surface water-HZ exchange. This is combined with reactive and/or sorptive streambed geomedia designed to remove dissolved phase contaminants from constructed urban drainage channels. Previous research at the Colorado School of Mines has shown that a 15-meter flume modified with BEST exhibits greater hyporheic exchange than an all-sand control flume, though both flumes provided greater contaminant attenuation than a selection of actual urban streams. This study again utilized the 15-meter flumes at Colorado School of Mines to evaluate two configurations of BEST for removal of heavy metals commonly found in stormwater runoff, including cadmium, copper, nickel, lead and zinc. In both BEST configurations, the geomedia consisted of a 30/70 (v/v) mix of woodchips and sand, with one configuration using coarse sand (K=0.48 cm/s) and the other using finer sand (K=0.16 cm/s). Both configurations were compared to an all-sand control. To evaluate metals removal, a suite of aqueous metals solution was spiked into each flume, and aqueous concentrations of the five metals of interest were monitored in both the surface and pore water over 24 hours. Differences in

  1. Professional ethics in biomedical engineering practice and research.

    Science.gov (United States)

    Monzon, Jorge E; Monzon-Wyngaard, Alvaro

    2008-01-01

    This paper discusses some guidelines for use with the accepted fundamental canons of ethics for engineers. We present some rules of practice and professional obligations emerging from these canons. Basic recommendations for engineers dissenting on ethical grounds are also presented. Ethical issues relating to Biomedical Engineering research are illustrated. We mention some cases that could be used to further understanding the ethical implications of biomedical engineering practice.

  2. Engineer, procure, construct (EPC) for nuclear projects in OPG

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, M. [Ontario Power Generation, Toronto, Ontario (Canada)

    2011-07-01

    OPG is exploring the use of EPC contracts for Nuclear Plant Design Modifications. Although OPG has used EPC outside of the nuclear island, this new initiative will begin to use EPC inside the plant, including upgrades to existing stations and mid-life refurbishment of Darlington. Benchmarking has shown that apart from new build, nuclear utilities rarely use this method inside the plant so OPG is using a step-by-step approach starting with projects with low complexity and low plant impact. The expected benefits are reduced interfaces and a simplified accountability model leading to schedule and cost improvements and lower rework. Design packages that incorporate construction input before issue will be a significant improvement. OPG's early challenges in moving to EPC include clearly defining roles, responsibilities and interfaces between the vendors and OPG, and modifying governance to match the new model. OPG intends to oversee the work while holding the vendor accountable for needs skill development on both sides. Vendors are expected to establish an engaged organization with complete knowledge of plant conditions, processes and streamlined methods to gain operations input. Vendors are also expected to identify and fix any quality issues before the modifications are commissioned and to have an in-house corrective action program to continuously improve. Vendors' early challenges include presenting one face to OPG rather than a collection of joint venture partners. This presentation describes OPG's plans and early feedback on this exciting new initiative.

  3. Engineer, procure, construct (EPC) for nuclear projects in OPG

    International Nuclear Information System (INIS)

    Elliott, M.

    2011-01-01

    OPG is exploring the use of EPC contracts for Nuclear Plant Design Modifications. Although OPG has used EPC outside of the nuclear island, this new initiative will begin to use EPC inside the plant, including upgrades to existing stations and mid-life refurbishment of Darlington. Benchmarking has shown that apart from new build, nuclear utilities rarely use this method inside the plant so OPG is using a step-by-step approach starting with projects with low complexity and low plant impact. The expected benefits are reduced interfaces and a simplified accountability model leading to schedule and cost improvements and lower rework. Design packages that incorporate construction input before issue will be a significant improvement. OPG's early challenges in moving to EPC include clearly defining roles, responsibilities and interfaces between the vendors and OPG, and modifying governance to match the new model. OPG intends to oversee the work while holding the vendor accountable for needs skill development on both sides. Vendors are expected to establish an engaged organization with complete knowledge of plant conditions, processes and streamlined methods to gain operations input. Vendors are also expected to identify and fix any quality issues before the modifications are commissioned and to have an in-house corrective action program to continuously improve. Vendors' early challenges include presenting one face to OPG rather than a collection of joint venture partners. This presentation describes OPG's plans and early feedback on this exciting new initiative.

  4. Construction of a bibliographic information database and development of retrieval system for research reports in nuclear science and technology (II)

    International Nuclear Information System (INIS)

    Han, Duk Haeng; Kim, Tae Whan; Choi, Kwang; Yoo, An Na; Keum, Jong Yong; Kim, In Kwon

    1996-05-01

    The major goal of this project is to construct a bibliographic information database in nuclear engineering and to develop a prototype retrieval system. To give an easy access to microfiche research report, this project has accomplished the construction of microfiche research reports database and the development of retrieval system. The results of the project are as follows; 1. Microfiche research reports database was constructed by downloading from DOE Energy, NTIS, INIS. 2. The retrieval system was developed in host and web version using access point such as title, abstracts, keyword, report number. 6 tabs., 8 figs., 11 refs. (Author) .new

  5. Construction of a bibliographic information database and development of retrieval system for research reports in nuclear science and technology (II)

    Energy Technology Data Exchange (ETDEWEB)

    Han, Duk Haeng; Kim, Tae Whan; Choi, Kwang; Yoo, An Na; Keum, Jong Yong; Kim, In Kwon [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-05-01

    The major goal of this project is to construct a bibliographic information database in nuclear engineering and to develop a prototype retrieval system. To give an easy access to microfiche research report, this project has accomplished the construction of microfiche research reports database and the development of retrieval system. The results of the project are as follows; 1. Microfiche research reports database was constructed by downloading from DOE Energy, NTIS, INIS. 2. The retrieval system was developed in host and web version using access point such as title, abstracts, keyword, report number. 6 tabs., 8 figs., 11 refs. (Author) .new.

  6. Research and exploration on nuclear safety culture construction

    International Nuclear Information System (INIS)

    Zhang Lifang; Zhao Hongtao; Wang Hongwei

    2012-01-01

    This thesis mainly researched the definition, characteristics, development stage and setup procedure concerning nuclear safety culture, based on practice and experiences in Technical Physics Institute of Heilongjian. Academy of Science. The author discussed the importance of nuclear safety culture construction for an enterprise of nuclear technology utilization, and emphasized all the enterprise and individual who engaged in nuclear and radiation safety should acquire good nuclear safety culture quality, and ensure the application and development of the nuclear safety cult.ure construction in the enterprises of nu- clear technological utilization. (authors)

  7. Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model.

    Science.gov (United States)

    Lee-Barthel, Ann; Baar, Keith; West, Daniel W D

    2017-06-11

    In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor. Thus, there is ample opportunity for alternative experimental approaches. Here we present an approach in which human cells are isolated from human anterior cruciate ligament tissue remnants, expanded in culture, and used to form engineered ligaments. Exercise alters the biochemical milieu in the blood such that the function of many tissues, organs and bodily processes are improved. In this experiment, ligament construct culture media was supplemented with experimental human serum that has been 'conditioned' by exercise. Thus the intervention is more biologically relevant since an experimental tissue is exposed to the full endogenous biochemical milieu, including binding proteins and adjunct compounds that may be altered in tandem with the activity of an unknown agent of interest. After treatment, engineered ligaments can be analyzed for mechanical function, collagen content, morphology, and cellular biochemistry. Overall, there are four major advantages versus traditional monolayer culture and animal models, of the physiological model of ligament tissue that is presented here. First, ligament constructs are three-dimensional, allowing for mechanical properties (i.e., function) such as ultimate tensile stress, maximal tensile load, and modulus, to be quantified. Second, the enthesis, the interface between boney and sinew elements, can be examined in detail and within functional context. Third, preparing media with post-exercise serum allows for the effects of the exercise-induced biochemical milieu, which is responsible for the wide range of health benefits of exercise, to be investigated in an unbiased manner. Finally, this experimental model advances scientific research in a humane and ethical manner by replacing the use of animals, a core mandate of the National

  8. Summary of Research 2001, Department of Mechanical Engineering, Graduate School of Engineering and Applied Sciences

    National Research Council Canada - National Science Library

    McNelley, Terry

    2002-01-01

    This report contains project summaries of the research projects in the Department of Mechanical Engineering A list of recent publications is also included, which consists of conference presentations...

  9. Strengthening engineering research and training in Africa

    International Development Research Centre (IDRC) Digital Library (Canada)

    Manfred Raffelsieper

    2017-08-14

    Aug 14, 2017 ... The engineering disciplines, in particular, could benefit from .... graduate education in Africa, with marked differences between ... particular attention to persistent structural barriers related to issues such as gender equality.

  10. Trend of the research on construction and demolition waste management

    International Nuclear Information System (INIS)

    Yuan Hongping; Shen Liyin

    2011-01-01

    Research interests in addressing construction and demolition (C and D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C and D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibit an increasing research interest in C and D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C and D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C and D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C and D waste management research, and this is considered a major methodology for future research in the discipline. C and D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C and D waste management has emerged as a new challenging topic.

  11. Trend of the research on construction and demolition waste management.

    Science.gov (United States)

    Yuan, Hongping; Shen, Liyin

    2011-04-01

    Research interests in addressing construction and demolition (C&D) waste management issues have resulted in a large amount of publications during the last decade. This study demonstrates that there is no systematic examination on the research development in literature in the discipline of C&D waste management. This study presents the latest research trend in the discipline through analyzing the publications from 2000 to 2009 in eight major international journals. The analysis is conducted on the number of papers published annually, main authors' contributions, research methods and data analysis methods adopted, and research topics covered. The results exhibit an increasing research interest in C&D waste management in recent years. Researchers from developed economies have contributed significantly to the development of the research in the discipline. Some developing countries such as Malaysia and China have also been making good efforts in promoting C&D waste management research. The findings from this study also indicate that survey and case study are major methods for data collection, and the data are mostly processed through descriptive analysis. It is anticipated that more future studies on C&D waste management will be led by researchers from developing economies, where construction works will remain their major economic activities. On the other hand, more sophisticated modeling and simulating techniques have been used effectively in a number of studies on C&D waste management research, and this is considered a major methodology for future research in the discipline. C&D waste management will continue to be a hot research topic in the future, in particularly, the importance of human factors in C&D waste management has emerged as a new challenging topic. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. Construction of Blaze at the University of Illinois at Chicago: A Shared, High-Performance, Visual Computer for Next-Generation Cyberinfrastructure-Accelerated Scientific, Engineering, Medical and Public Policy Research

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Maxine D. [Acting Director, EVL; Leigh, Jason [PI

    2014-02-17

    The Blaze high-performance visual computing system serves the high-performance computing research and education needs of University of Illinois at Chicago (UIC). Blaze consists of a state-of-the-art, networked, computer cluster and ultra-high-resolution visualization system called CAVE2(TM) that is currently not available anywhere in Illinois. This system is connected via a high-speed 100-Gigabit network to the State of Illinois' I-WIRE optical network, as well as to national and international high speed networks, such as the Internet2, and the Global Lambda Integrated Facility. This enables Blaze to serve as an on-ramp to national cyberinfrastructure, such as the National Science Foundation’s Blue Waters petascale computer at the National Center for Supercomputing Applications at the University of Illinois at Chicago and the Department of Energy’s Argonne Leadership Computing Facility (ALCF) at Argonne National Laboratory. DOE award # DE-SC005067, leveraged with NSF award #CNS-0959053 for “Development of the Next-Generation CAVE Virtual Environment (NG-CAVE),” enabled us to create a first-of-its-kind high-performance visual computing system. The UIC Electronic Visualization Laboratory (EVL) worked with two U.S. companies to advance their commercial products and maintain U.S. leadership in the global information technology economy. New applications are being enabled with the CAVE2/Blaze visual computing system that is advancing scientific research and education in the U.S. and globally, and help train the next-generation workforce.

  13. Quality assurance and quality control of nuclear engineering during construction phase

    International Nuclear Information System (INIS)

    Zhang Zhihua; Deng Yue; Liu Yaoguang; Xu Xianqi; Zhou Shan; Qian Dazhi; Zhang Yang

    2007-01-01

    The quality assurance (QA) and quality control (QC) is a very important work in the nuclear engineering. This paper starts with how to establish quality assurance system of nuclear engineering construction phase, then introduces several experiments and techniques such as the implementation of quality assurance program, the quality assurance and quality control of contractors, the quality surveillance and control of supervisory companies, quality assurance audit and surveillance of builders. (authors)

  14. A systematic literature review of resilience engineering: Research areas and a research agenda proposal

    International Nuclear Information System (INIS)

    Righi, Angela Weber; Saurin, Tarcisio Abreu; Wachs, Priscila

    2015-01-01

    Resilience engineering (RE) has been advocated as a new safety management paradigm, compatible with the nature of complex socio-technical systems. This study aims to identify the research areas and to propose a research agenda for RE, based on a systematic literature review that encompasses 237 studies from 2006 to 2014. Six research areas are identified: theory of RE; identification and classification of resilience; safety management tools; analysis of accidents; risk assessment; and training. The area “theory of RE” accounted for 52% of the studies, and it indicates that research has emphasized the description of how resilient performance occurs. The proposal for a research agenda is focused on: refining key constructs; positioning RE in relation to other theories; exploring other research strategies in addition to case-based studies; investigating barriers for implementing RE; and balancing the importance on describing and understanding resilience with the emphasis on the design of resilient systems, and the evaluation of these designs. - Highlights: • Six research areas on RE are identified. • A research agenda for RE is proposed. • RE research is mostly descriptive and based on case studies. • Design science is suggested as a research strategy for RE. • Five domains account for 75% of the reviewed studies

  15. Construction of a bibliographic information database for the nuclear engineering

    International Nuclear Information System (INIS)

    Kim, Tae Whan; Lim, Yeon Soo; Kwac, Dong Chul

    1991-12-01

    The major goal of the project is to develop a nuclear science database of materials that have been published in Korea and to establish a network system that will give relevant information to people in the nuclear industry by linking this system with the proposed National Science Technical Information Network. This project aims to establish a database consisted of about 1,000 research reports that were prepared by KAERI from 1979 to 1990. The contents of the project are as follows: 1. Materials Selection and Collection 2. Index and Abstract Preparation 3. Data Input and Transmission. This project is intended to achieve the goal of maximum utilization of nuclear information in Korea. (Author)

  16. CONTEMPORARY DOMESTIC RESEARCH OF PSYCHOLOGY OF CONSTRUCTING THE FUTURE

    Directory of Open Access Journals (Sweden)

    Alexey Vladimirovich Mikhalsky

    2015-11-01

    Full Text Available This article discusses the modern domestic research in the field of psychology of future perception and construction. Time, space, events only become meaningful when a position of observer arises, and when people are directly and vividly involved into them. The presence of human perception – an essential attribute of comprehension, appearance of the value for the time and space, in other words – the attribution of values – a separate measurement, giving the existence of time and space, allowing the existence of semantic relations, an integral component of constructing the future. An array of publications, images, ideas, «memes» on constructing the future is becoming more voluminous, but at the same time, it is very difficult to trace the evolution of a single line of ideas, concepts, theories, research directions, scientific and philosophical approaches to the practical aspects of use. The proposed concept and practical approach of contemporary researchers define a new impetus to scientific research, serves as the basis for practices and, perhaps, is the philosophy that is needed humanity, standing on sharp blades to survive in conditions of information overload, uncertainty and economic fluctuations, on the verge of which can not go – on the verge of using weapons of mass destruction, global international, cross-cultural encounters.

  17. Journal of Civil Engineering Research and Practice: Submissions

    African Journals Online (AJOL)

    Author Guidelines. AIMS AND SCOPE The Journal of Civil Engineering Research and Practice aims to publish original research papers of high standard, containing material of broad interest and of significant contribution to civil engineering, with emphasis being placed on material that is applicable to the solution of ...

  18. Nuclear science and engineering education at a university research reactor

    International Nuclear Information System (INIS)

    Loveland, W.

    1993-01-01

    The role of an on-site irradiation facility in nuclear science and engineering education is examined. Using the example of a university research reactor, the use of such devices in laboratory instruction, public outreach programs, special instructional programs, research, etc. is discussed. Examples from the Oregon State University curriculum in nuclear chemistry, nuclear engineering and radiation health are given. (author) 1 tab

  19. Interdisciplinary Research for Engineering Skills Development Interdisciplinary Research for Engineering Skills Development

    Directory of Open Access Journals (Sweden)

    Angel E. González-Lizardo

    2012-02-01

    Full Text Available Este trabajo reporta los resultados de una experiencia interdisciplinaria de investigaciónpara estudiantes de ingeniería, en el Laboratorio de Ingeniería de Plasma (PEL por sussiglas en inglés de la Universidad Politécnica de Puerto Rico (UPPR. Los rasgos fuertes de esta experiencia y su relación con los resultados esperados por la Junta de Acreditación para Ingeniería y Tecnología (ABET por sus siglas en inglés son destacados, y una descripción cualitativa de los resultados en términos de la ejecución de los estudiantes durante la experiencia y después de ella. Se presenta un ejemplo de las diferentes actividades realizadas por un equipo de estudiantes subgraduados y su relación con los resultados esperados por ABET. La experiencia de investigación en el PEL provee a los estudiantes con una oportunidad única para practicar la ingeniería antes de su graduación, a través de problemas reales, innovación, colaboración con otras instituciones, y presentación de su trabajo a audiencias de científicos e ingenieros. This work reports the results of an ad hoc interdisciplinary research experience for undergraduate engineering students at the Plasma Engineering Laboratory (PEL of the Polytechnic University of Puerto Rico (PUPR. The strong features of this experience and their relationship with Accreditation Board for Engineering and Technology (ABET outcomes are pointed out, and a qualitative description of the results is discussed, in terms of the performance of the students during the experience and after it. An example of the different activities performed by a team of undergraduate students, and their relationship with the ABET outcomes is presented. The undergraduate research at the PEL provides the students with a unique opportunity to practice engineering before graduation through real life problems, innovation, collaboration with other institutions, and presentation of their work for engineering and scientific audiences.

  20. Barriers to the Uptake of Concurrent Engineering in the Nigerian Construction Industry

    OpenAIRE

    Aniekwu, Nathaniel Anny; Igboanugo, Anthony C.

    2012-01-01

    It is the consensus of scholars that the productivity of the construction industry is very low when compared with other industries. Concurrent Engineering (CE), which has a primary goal of reducing the total time from designing a product to releasing it into the market, while creating better designs as well, has been identified as one of the concepts that has yielded effective adaptation in the construction industry. An exploratory survey was used to identify 63 variables with the capacity to...

  1. Trends of researches for fusion engineering research facility (FERF)

    International Nuclear Information System (INIS)

    Ozawa, Yasutomo; Enoto, Takeaki

    1975-01-01

    The role of a fusion neutron radiation test facility in the development of a scientific feasibility experimental reactor or demonstration fusion power reactor plant would be analogous to the role of the materials testing and experimental reactors in the development of fission power reactor. While the material testing fission reactor has been developed after successful operation of fission reactors, in the case of fusion reactor development it is desirable to realize the fusion engineering research facility (FERF) in-phase to the development of SFX and/or demonstration fusion power reactor plants. Here so called FERF in near future is the Controlled Thermonuclear Reactor which provides the high-intensity and high-energy neutron and plasma source whether the net power output is produced or not. From the point of direct attainment to SFX, we would like to emphasize that FEFE is the royal road leading to the goal of successful achievement of CTR program and could be useful for the experiment on impurity effects caused by neutron and plasma irradiations onto the wall material for SFX. Further, we rather suppose that hybrid FERF-fission assembly could be fairly and easily realizable in near future. (auth.)

  2. Functional evaluation of artificial skeletal muscle tissue constructs fabricated by a magnetic force-based tissue engineering technique.

    Science.gov (United States)

    Yamamoto, Yasunori; Ito, Akira; Fujita, Hideaki; Nagamori, Eiji; Kawabe, Yoshinori; Kamihira, Masamichi

    2011-01-01

    Skeletal muscle tissue engineering is currently applied in a variety of research fields, including regenerative medicine, drug screening, and bioactuator development, all of which require the fabrication of biomimic and functional skeletal muscle tissues. In the present study, magnetite cationic liposomes were used to magnetically label C2C12 myoblast cells for the construction of three-dimensional artificial skeletal muscle tissues by an applied magnetic force. Skeletal muscle functions, such as biochemical and contractile properties, were evaluated for the artificial tissue constructs. Histological studies revealed that elongated and multinucleated myotubes were observed within the tissue. Expression of muscle-specific markers, such as myogenin, myosin heavy chain and tropomyosin, were detected in the tissue constructs by western blot analysis. Further, creatine kinase activity increased during differentiation. In response to electric pulses, the artificial tissue constructs contracted to generate a physical force (the maximum twitch force, 33.2 μN [1.06 mN/mm2]). Rheobase and chronaxie of the tissue were determined as 4.45 V and 0.72 ms, respectively. These results indicate that the artificial skeletal muscle tissue constructs fabricated in this study were physiologically functional and the data obtained for the evaluation of their functional properties may provide useful information for future skeletal muscle tissue engineering studies.

  3. Constructing engineers through practice: Gendered features of learning and identity development

    Science.gov (United States)

    Tonso, Karen L.

    How do women and men student engineers develop an engineering identity (a sense of belonging, or not), while practicing "actual" engineering? What are the influences of gender, learning and knowledge, relations of power, and conceptions of equality on cultural identity development? I studied these issues in reform-minded engineering design classes, courses organized around teaching students communications, teamwork, and practical engineering. Engineering-student cultural identity categories revealed a status hierarchy, predicated on meeting "academic" criteria for excellence, and the almost total exclusion of women. While working as an engineering colleague on five student teams (three first-year and two senior) and attending their design classes, I documented how cultural identities were made evident and constructed in students' practical engineering. Design projects promoted linking academic knowledge with real-world situations, sharing responsibilities and trusting colleagues, communicating engineering knowledge to technical and non-technical members of business communities, and addressing gaps in students' knowledge. With a curriculum analysis and survey of students' perceptions of the differences between design and conventional courses, I embedded the design classes in the wider campus and found that: (1) Engineering education conferred prestige, power, and well-paying jobs on students who performed "academic" engineering, while failing to adequately encourage "actual" engineering practices. High-status student engineers were the least likely to perform "actual" engineering in design teams. (2) Engineering education advanced an ideology that encouraged its practitioners to consider men's privilege and women's invisibility normal. By making "acting like men act" the standards to which engineering students must conform, women learned to put up with oppressive treatment. Women's accepting their own mistreatment and hiding their womanhood became a condition of

  4. The design and construction of an electrohydrodynamic cartesian robot for the preparation of tissue engineering constructs.

    Directory of Open Access Journals (Sweden)

    Shaikh Hafeez Hashimdeen

    Full Text Available In this work we bring together replicating rapid prototyping technology with electrohydrodynamic phenomena to develop a device with the ability to build structures in three-dimensions while simultaneously affording the user a degree of designing versatility and ease that is not seen in conventional computer numerically controlled machines. An attempt at reproducing an actual human ear using polycaprolactone was pursued to validate the hardware. Five different polycaprolactone solution concentrations between 7-15 wt% were used and printing was performed at applied voltages that ranged from 1 to 6 kV and at flow rates from 5 µl/min to 60 µl/min. The corresponding geometrical and aesthetic features of the printed constructs were studied to determine the effectiveness of the device. The 15 wt% concentration at 60 µl/min under an applied electric field of 6 kV was identified as the best operating parameters to work with.

  5. Researches on direct injection in internal-combustion engines

    Science.gov (United States)

    Tuscher, Jean E

    1941-01-01

    These researches present a solution for reducing the fatigue of the Diesel engine by permitting the preservation of its components and, at the same time, raising its specific horsepower to a par with that of carburetor engines, while maintaining for the Diesel engine its perogative of burning heavy fuel under optimum economical conditions. The feeding of Diesel engines by injection pumps actuated by engine compression achieves the required high speeds of injection readily and permits rigorous control of the combustible charge introduced into each cylinder and of the peak pressure in the resultant cycle.

  6. Research regarding reverse engineering for aircraft components

    Directory of Open Access Journals (Sweden)

    Udroiu Razvan

    2017-01-01

    Full Text Available Reverse engineering is a useful technique used in manufacturing and design process of new components. In aerospace industry new components can be developed, based on existing components without technical Computer Aided Design (CAD data, in order to reduce the development cycle of new products. This paper proposes a methodology wherein the CAD model of turbine blade can be build using computer aided reverse engineering technique utilising a 5 axis Coordinate Measuring Machine (CMM. The proposed methodology uses a scanning strategy by features, followed by a design methodology for 3D modelling of complex shapes.

  7. The research on teaching reformation of photoelectric information science and engineering specialty experiments

    Science.gov (United States)

    Zhu, Zheng; Yang, Fan; Zhang, Yang; Geng, Tao; Li, Yuxiang

    2017-08-01

    This paper introduced the idea of teaching reformation of photoelectric information science and engineering specialty experiments. The teaching reformation of specialty experiments was analyzed from many aspects, such as construction of specialized laboratory, experimental methods, experiment content, experiment assessing mechanism, and so on. The teaching of specialty experiments was composed of four levels experiments: basic experiments, comprehensive and designing experiments, innovative research experiments and engineering experiments which are aiming at enterprise production. Scientific research achievements and advanced technology on photoelectric technology were brought into the teaching of specialty experiments, which will develop the students' scientific research ability and make them to be the talent suitable for photoelectric industry.

  8. Growth factor stimulation improves the structure and properties of scaffold-free engineered auricular cartilage constructs.

    Directory of Open Access Journals (Sweden)

    Renata G Rosa

    Full Text Available The reconstruction of the external ear to correct congenital deformities or repair following trauma remains a significant challenge in reconstructive surgery. Previously, we have developed a novel approach to create scaffold-free, tissue engineering elastic cartilage constructs directly from a small population of donor cells. Although the developed constructs appeared to adopt the structural appearance of native auricular cartilage, the constructs displayed limited expression and poor localization of elastin. In the present study, the effect of growth factor supplementation (insulin, IGF-1, or TGF-β1 was investigated to stimulate elastogenesis as well as to improve overall tissue formation. Using rabbit auricular chondrocytes, bioreactor-cultivated constructs supplemented with either insulin or IGF-1 displayed increased deposition of cartilaginous ECM, improved mechanical properties, and thicknesses comparable to native auricular cartilage after 4 weeks of growth. Similarly, growth factor supplementation resulted in increased expression and improved localization of elastin, primarily restricted within the cartilaginous region of the tissue construct. Additional studies were conducted to determine whether scaffold-free engineered auricular cartilage constructs could be developed in the 3D shape of the external ear. Isolated auricular chondrocytes were grown in rapid-prototyped tissue culture molds with additional insulin or IGF-1 supplementation during bioreactor cultivation. Using this approach, the developed tissue constructs were flexible and had a 3D shape in very good agreement to the culture mold (average error <400 µm. While scaffold-free, engineered auricular cartilage constructs can be created with both the appropriate tissue structure and 3D shape of the external ear, future studies will be aimed assessing potential changes in construct shape and properties after subcutaneous implantation.

  9. The laboratory test rig with miniature jet engine to research aviation fuels combustion process

    Directory of Open Access Journals (Sweden)

    Gawron Bartosz

    2015-12-01

    Full Text Available This article presents laboratory test rig with a miniature turbojet engine (MiniJETRig – Miniature Jet Engine Test Rig, that was built in the Air Force Institute of Technology. The test rig has been developed for research and development works aimed at modelling and investigating processes and phenomena occurring in full scale jet engines. In the article construction of a test rig is described, with a brief discussion on the functionality of each of its main components. Additionally examples of measurement results obtained during the realization of the initial tests have been included, presenting the capabilities of the test rig.

  10. Increase of the contract amounts for LHC civil-engineering construction and civil-engineering consultancy contracts

    CERN Document Server

    2005-01-01

    This document concerns the increase of the contract amounts for LHC civil-engineering construction and civil-engineering consultancy, Package 2. The Finance Committee is invited to take note of the increase of the contract amounts with: - the joint venture DRAGADOS (ES) and SELI (IT) for civil-engineering construction, LHC Package 2, for an amount of 28 087 000 Swiss francs, subject to revision, in the amount previously announced to Finance Committee (CERN/FC/4516) of 132 200 000 Swiss francs, subject to revision, bringing the total to a maximum amount of 160 287 000 Swiss francs, subject to revision. - the joint venture GIBB (GB), GEOCONSULT (AT) and SGI (CH) for the provision of civil-engineering consultancy services, LHC Package 2, for an amount of 900 000 Swiss francs, subject to revision, in the amount previously announced to Finance Committee of 13 800 000 Swiss francs, subject to revision, bringing the total to a maximum amount of 14 700 000 Swiss francs, subject to revision

  11. Is Engineering Design Disappearing from Design Research?

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Howard, Thomas J.

    2011-01-01

    Most systems and products need to be engineered during their design, based upon scientific insight into principles, mechanisms, materials and production pos-sibilities, leading to reliability, durability and value for the user. Despite the central importance and design’s crucial dependency...

  12. Recent Approaches in Tooth Engineering Research

    Czech Academy of Sciences Publication Activity Database

    Švandová, Eva; Veselá, Barbora; Křivánek, J.; Hampl, A.; Matalová, Eva

    2014-01-01

    Roč. 60, Suppl 1 (2014), s. 21-29 ISSN 0015-5500 R&D Projects: GA ČR GAP304/11/1418; GA MZd(CZ) NT11420 Institutional support: RVO:67985904 Keywords : engineering * tooth * stem cells * culture techniques Subject RIV: EA - Cell Biology Impact factor: 1.000, year: 2014

  13. Status of Research in Biomedical Engineering 1968.

    Science.gov (United States)

    National Inst. of General Medical Sciences (NIH), Bethesda, MD.

    This status report is divided into eight sections. The first four represent the classical engineering or building aspects of bioengineering and deal with biomedical instrumentation, prosthetics, man-machine systems and computer and information systems. The next three sections are related to the scientific, intellectual and academic influence of…

  14. Multimillion Dollar Construction Project Completed in Glenn's Icing Research Tunnel

    Science.gov (United States)

    Kevdzija, Susan L.

    2001-01-01

    Over the last year, the Glenn Research Center's Icing Research Tunnel (IRT) underwent a major $5.2 million rehabilitation project as part of the Construction of Facilities program. The scope of the project included redesign and replacement of the 55-yr-old heat exchanger, the addition of fan outlet guide vanes for flow conditioning downstream of the 25-ft-diameter fan, and redesign and replacement of the C and D corner-turning vanes. The purpose of the rehabilitation was to replace old portions of the infrastructure and to improve the aerodynamic flow quality in the tunnel.

  15. Characterization and comparative investigation of thermally insulating layers for the turbine and engine construction

    International Nuclear Information System (INIS)

    Steffens, H.D.; Fischer, U.

    1987-01-01

    The aim of the research project was to subject commercially produced thermal insulation layer systems, the use of which seems promising for engine and turbine construction, to standardized characterisation, testing and comparison. Suitable methods and procedures for this had to be developed, in order to be able to derive instructions for optimisation guidelines for the production of improved thermal insulation systems from the results of investigations. In the context of the research project, a computer-controlled thermal shock test rig was first developed, designed and built. This test rig was designed so that important test conditions, such as the heating and cooling speed could be varied reproducibly over wide ranges. Methods and procedures were worked out, which permit a comparative qualitative and quantitative characterisation of layers of thermal insulation. From metallographic investigations, the layer build-up, layer structure, porosity and crack morphology of the layers in the delivered state and after testing could be assessed and compared. X-ray fine structure investigations gave information on the type and quantity of the phases occurring in the ceramic layers. The results of thermal shock tests which were done at different temperature intervals depending on the substrate, could be correlated with the build-up of layers and supplied information on damage mechanisms and the course of failure. (orig.) With 57 figs., 16 tabs., 89 refs [de

  16. Variation in tissue outcome of ovine and human engineered heart valve constructs : relevance for tissue engineering

    NARCIS (Netherlands)

    Geemen, van D.; Driessen - Mol, A.; Grootzwagers, L.G.M.; Soekhradj - Soechit, R.S.; Riem Vis, P.W.; Baaijens, F.P.T.; Bouten, C.V.C.

    AIM: Clinical application of tissue engineered heart valves requires precise control of the tissue culture process to predict tissue composition and mechanical properties prior to implantation, and to understand the variation in tissue outcome. To this end we investigated cellular phenotype and

  17. How to Construct a Mixed Methods Research Design.

    Science.gov (United States)

    Schoonenboom, Judith; Johnson, R Burke

    2017-01-01

    This article provides researchers with knowledge of how to design a high quality mixed methods research study. To design a mixed study, researchers must understand and carefully consider each of the dimensions of mixed methods design, and always keep an eye on the issue of validity. We explain the seven major design dimensions: purpose, theoretical drive, timing (simultaneity and dependency), point of integration, typological versus interactive design approaches, planned versus emergent design, and design complexity. There also are multiple secondary dimensions that need to be considered during the design process. We explain ten secondary dimensions of design to be considered for each research study. We also provide two case studies showing how the mixed designs were constructed.

  18. An antibody based approach for multi-coloring osteogenic and chondrogenic proteins in tissue engineered constructs.

    Science.gov (United States)

    Leferink, Anne M; Reis, Diogo Santos; van Blitterswijk, Clemens A; Moroni, Lorenzo

    2018-04-11

    When tissue engineering strategies rely on the combination of three-dimensional (3D) polymeric or ceramic scaffolds with cells to culture implantable tissue constructs in vitro, it is desirable to monitor tissue growth and cell fate to be able to more rationally predict the quality and success of the construct upon implantation. Such a 3D construct is often referred to as a 'black-box' since the properties of the scaffolds material limit the applicability of most imaging modalities to assess important construct parameters. These parameters include the number of cells, the amount and type of tissue formed and the distribution of cells and tissue throughout the construct. Immunolabeling enables the spatial and temporal identification of multiple tissue types within one scaffold without the need to sacrifice the construct. In this report, we concisely review the applicability of antibodies (Abs) and their conjugation chemistries in tissue engineered constructs. With some preliminary experiments, we show an efficient conjugation strategy to couple extracellular matrix Abs to fluorophores. The conjugated probes proved to be effective in determining the presence of collagen type I and type II on electrospun and additive manufactured 3D scaffolds seeded with adult human bone marrow derived mesenchymal stromal cells. The conjugation chemistry applied in our proof of concept study is expected to be applicable in the coupling of any other fluorophore or particle to the Abs. This could ultimately lead to a library of probes to permit high-contrast imaging by several imaging modalities.

  19. Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: Measurement and modeling

    NARCIS (Netherlands)

    Malda, J.; Rouwkema, Jeroen; Martens, D.E.; le Comte, EP; Kooy, F.K.; Tramper, J.; van Blitterswijk, Clemens; Riesle, J.U.

    2004-01-01

    The supply of oxygen within three-dimensional tissue-engineered (TE) cartilage polymer constructs is mainly by diffusion. Oxygen consumption by cells results in gradients in the oxygen concentration. The aims of this study were, firstly, to identify the gradients within TE cartilage polymer

  20. Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling

    NARCIS (Netherlands)

    Malda, J.; Rouwkema, J.; Martens, D.E.; Paul le Comte, E.; Kooy, F.K.; Tramper, J.; Blitterswijk, van C.A.; Riesle, J.

    2004-01-01

    The supply of oxygen within three-dimensional tissue-engineered (TE) cartilage polymer constructs is mainly by diffusion. Oxygen consumption by cells results in gradients in the oxygen concentration. The aims of this study were, firstly, to identify the gradients within TE: cartilage polymer

  1. The effect of PEGT/PBT scaffold architecture on oxygen gradients in tissue engineered cartilaginous constructs

    NARCIS (Netherlands)

    Malda, J.; Woodfield, T.B.F.; van der Vloodt, F.; Kooy, F.K.; Martens, D.E.; Tramper, J.C.; van Blitterswijk, Clemens; Riesle, J.U.

    2004-01-01

    Repair of articular cartilage defects using tissue engineered constructs composed of a scaffold and cultured autologous cells holds promise for future treatments. However, nutrient limitation (e.g. oxygen) has been suggested as a cause of the onset of chondrogenesis solely within the peripheral

  2. Evolutionary, Unconscious Design Support for the Architectural, Engineering and Construction Industry

    NARCIS (Netherlands)

    Van de Ruitenbeek, H.K.M.

    2012-01-01

    The Architecture, Engineering and Construction (AEC) industry is a complex system in which carpenters, structural designers, architects, modellers, cost estimators, planners, politicians and many others act apart together in project-specific virtual enterprises. There is a large amount of actors, an

  3. Tool for Benchmarking BIM Performance of Design Engineering and Construction Firms in The Netherlands

    NARCIS (Netherlands)

    Sebastian, R.; Berlo, L. van

    2010-01-01

    Building information modelling (BIM) is becoming more and more important to manage complex communication and information sharing processes in collaborative building projects. A growing number of design, engineering and construction firms have made attempts to adopt BIM to enhance their services and

  4. Facilitating Constructive Alignment in Power Systems Engineering Education Using Free and Open-Source Software

    Science.gov (United States)

    Vanfretti, L.; Milano, F.

    2012-01-01

    This paper describes how the use of free and open-source software (FOSS) can facilitate the application of constructive alignment theory in power systems engineering education by enabling the deep learning approach in power system analysis courses. With this aim, this paper describes the authors' approach in using the Power System Analysis Toolbox…

  5. Management Model for Evaluation and Selection of Engineering Equipment Suppliers for Construction Projects in Iraq

    Directory of Open Access Journals (Sweden)

    Kadhim Raheem Erzaij

    2016-06-01

    Full Text Available Engineering equipment is essential part in the construction project and usually manufactured with long lead times, large costs and special engineering requirements. Construction manager targets that equipment to be delivered in the site need date with the right quantity, appropriate cost and required quality, and this entails an efficient supplier can satisfy these targets. Selection of engineering equipment supplier is a crucial managerial process .it requires evaluation of multiple suppliers according to multiple criteria. This process is usually performed manually and based on just limited evaluation criteria, so better alternatives may be neglected. Three stages of survey comprised number of public and private companies in Iraqi construction sector were employed to identify main criteria and sub criteria for supplier selection and their priorities.The main criteria identified were quality of product, commercial aspect, delivery, reputation and position, and system quality . An effective technique in multiple criteria decision making (MCDM as analytical hierarchy process (AHP have been used to get importance weights of criteria based on experts judgment. Thereafter, a management software system for Evaluation and Selection of Engineering Equipment Suppliers (ESEES has been developed based on the results obtained from AHP. This model was validated in a case study at municipality of Baghdad involved actual cases of selection pumps suppliers for infrastructure projects .According to experts, this model can improve the current process followed in the supplier selection and aid decision makers to adopt better choices in the domain of selection engineering equipment suppliers.

  6. Morphological changes in paraurethral area after introduction of tissue engineering construct on the basis of adipose tissue stromal cells.

    Science.gov (United States)

    Makarov, A V; Arutyunyan, I V; Bol'shakova, G B; Volkov, A V; Gol'dshtein, D V

    2009-10-01

    We studied morphological changes in the paraurethral area of Wistar rats after introduction of tissue engineering constructs on the basis of multipotent mesenchymal stem cells and gelatin sponge. The tissue engineering construct containing autologous culture of the stromal fraction of the adipose tissue was most effective. After introduction of this construct we observed more rapid degradation of the construct matrix and more intensive formation of collagen fibers.

  7. Monitoring sinew contraction during formation of tissue-engineered fibrin-based ligament constructs.

    Science.gov (United States)

    Paxton, Jennifer Z; Wudebwe, Uchena N G; Wang, Anqi; Woods, Daniel; Grover, Liam M

    2012-08-01

    The ability to study the gross morphological changes occurring during tissue formation is vital to producing tissue-engineered structures of clinically relevant dimensions in vitro. Here, we have used nondestructive methods of digital imaging and optical coherence tomography to monitor the early-stage formation and subsequent maturation of fibrin-based tissue-engineered ligament constructs. In addition, the effect of supplementation with essential promoters of collagen synthesis, ascorbic acid (AA) and proline (P), has been assessed. Contraction of the cell-seeded fibrin gel occurs unevenly within the first 5 days of culture around two fixed anchor points before forming a longitudinal ligament-like construct. AA+P supplementation accelerates gel contraction in the maturation phase of development, producing ligament-like constructs with a higher collagen content and distinct morphology to that of unsupplemented constructs. These studies highlight the importance of being able to control the methods of tissue formation and maturation in vitro to enable the production of tissue-engineered constructs with suitable replacement tissue characteristics for repair of clinical soft-tissue injuries.

  8. Overcoming recruitment challenges in construction safety intervention research.

    Science.gov (United States)

    Kidd, Pamela; Parshall, Mark; Wojcik, Susan; Struttmann, Tim

    2004-03-01

    Recruiting workers in small construction companies and securing their participation in voluntary safety programs or safety research poses unique challenges. Worker turnover and worksite changes contribute to difficulties in locating and enrolling participants. Economic pressures and time demands potentially threaten ongoing participation. Six simulation exercises designed to reduce back and fall injuries in small construction companies were developed based on data from focus groups of workers and company owners. Working with a workers' compensation insurer, we had access to owner-operators of general, heavy, and special trade construction companies reporting less than $10,000 in payroll expenses. Recruitment methods included a participation incentive, mailed invitations followed by phone contacts, and follow-up reminders. Despite using recruitment methods recommended in the literature, participation rates were low over a 2-year intervention period. Because of these difficulties, factors affecting participation or nonparticipation became an additional research focus. Owners' perceptions of already having a good safety record and of the time demands of participation were the most commonly cited reasons for not participating. Literature on recruitment emphasizes processes and procedures under investigator control rather than understanding potential participants' judgments about the adequacy of their existing practices and the potential benefits of intervention participation relative to potential time and productivity trade-offs. Greater attention to such judgments may enhance recruitment and participation in under-studied and difficult to access populations. Copyright 2004 Wiley-Liss, Inc.

  9. Thrust Area Report, Engineering Research, Development and Technology

    Energy Technology Data Exchange (ETDEWEB)

    Langland, R. T.

    1997-02-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the knowledge base, process technologies, specialized equipment, tools and facilities to support current and future LLNL programs. Engineering`s efforts are guided by a strategy that results in dual benefit: first, in support of Department of Energy missions, such as national security through nuclear deterrence; and second, in enhancing the nation`s economic competitiveness through our collaboration with U.S. industry in pursuit of the most cost- effective engineering solutions to LLNL programs. To accomplish this mission, the Engineering Research, Development, and Technology Program has two important goals: (1) identify key technologies relevant to LLNL programs where we can establish unique competencies, and (2) conduct high-quality research and development to enhance our capabilities and establish ourselves as the world leaders in these technologies. To focus Engineering`s efforts technology {ital thrust areas} are identified and technical leaders are selected for each area. The thrust areas are comprised of integrated engineering activities, staffed by personnel from the nine electronics and mechanical engineering divisions, and from other LLNL organizations. This annual report, organized by thrust area, describes Engineering`s activities for fiscal year 1996. The report provides timely summaries of objectives, methods, and key results from eight thrust areas: Computational Electronics and Electromagnetics; Computational Mechanics; Microtechnology; Manufacturing Technology; Materials Science and Engineering; Power Conversion Technologies; Nondestructive Evaluation; and Information Engineering. Readers desiring more information are encouraged to contact the individual thrust area leaders or authors. 198 refs., 206 figs., 16 tabs.

  10. Research Skills Enhancement in Future Mechanical Engineers

    Directory of Open Access Journals (Sweden)

    Jorge Lino Alves

    2011-04-01

    Full Text Available Nowadays, the Web is a common tool for students searching information about the subjects taught in the different university courses. Although this is a good tool for the first rapid knowledge, a deeper study is usually demanded.

    After many years of teaching a course about ceramic and composite materials in the Integrated Master in Mechanical Engineering of Faculty of Engineering of University of Porto, Portugal, the authors used the Bologna reformulation of the mechanical engineering course to introduce new teaching methodologies based on a project based learning methodology.

    One of the main innovations is a practical work that comprises the study of a recent ceramic scientific paper, using all the actual available tools, elaboration of a scientific report, work presentation and participation in a debate.

    With this innovative teaching method the enrolment of the students was enhanced with a better knowledge about the ceramics subject and the skills related with the CDIO competences.

    This paper presents the reasons for this implementation and explains the teaching methodology adopted as well as the changes obtained in the students’ final results.

  11. Engineered surface barriers for waste disposal sites: lysimeter facility design and construction

    International Nuclear Information System (INIS)

    Phillips, S.J.; Ruben, M.S.; Kirkham, R.R.

    1988-01-01

    A facility to evaluate performance of engineered surface carriers for confinement of buried wastes has been designed, constructed, and operations initiated. The Field Lysimeter Test Facility is located at the US Department of Energy's Hanford Site in Richland, Washington. The facility consists of 18 one-dimensional drainage and weighing lysimeters used to evaluate 7 replicated barrier treatments. Distinct layers of natural earth materials were used to construct layered soil and rock barriers in each lysimeter. These barrier designs are capable in principal of significantly reducing or precluding infiltration of meteoric water through barriers into underlying contaminated zones. This paper summarizes salient facility design and construction features used in testing of the Hanford Site's engineered surface barriers

  12. Design and Construction of Pool Door for Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Kwangsub; Lee, Sangjin; Choi, Jinbok; Oh, Jinho; Lee, Jongmin [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The pool door is a structure to isolate the reactor pool from the service pool for maintenance. The pool door is installed before the reactor pool is drained. The pool door consists of structural component and sealing component. The main structures of the pool door are stainless steel plates and side frames. The plates and frames are assembled by welded joints. Lug is welded at the top of the plate. The pool door is submerged in the pool water when it is used. Materials of the pool door should be resistive to corrosion and radiation. Stainless steel is used in structural components and air nozzle assemblies. Features of design and construction of the pool door for the research reactor are introduced. The pool door is designed to isolate the reactor pool for maintenance. Structural analysis is performed to evaluate the structural integrity during earthquake. Tests and inspections are also carried out during construction to identify the safety and function of the pool door.

  13. Design and Construction of Pool Door for Research Reactor

    International Nuclear Information System (INIS)

    Jung, Kwangsub; Lee, Sangjin; Choi, Jinbok; Oh, Jinho; Lee, Jongmin

    2016-01-01

    The pool door is a structure to isolate the reactor pool from the service pool for maintenance. The pool door is installed before the reactor pool is drained. The pool door consists of structural component and sealing component. The main structures of the pool door are stainless steel plates and side frames. The plates and frames are assembled by welded joints. Lug is welded at the top of the plate. The pool door is submerged in the pool water when it is used. Materials of the pool door should be resistive to corrosion and radiation. Stainless steel is used in structural components and air nozzle assemblies. Features of design and construction of the pool door for the research reactor are introduced. The pool door is designed to isolate the reactor pool for maintenance. Structural analysis is performed to evaluate the structural integrity during earthquake. Tests and inspections are also carried out during construction to identify the safety and function of the pool door

  14. Biomedical engineering: A platform for research and innovation in ultrasound

    Science.gov (United States)

    Holland, Christy K.

    2004-05-01

    An undergraduate or graduate degree in biomedical engineering prepares students to solve problems at the interface between engineering and medicine. Biomedical engineering encompasses evolving areas such as advanced medical imaging for diagnosis and treatment of disease, tissue engineering for designing and manufacturing biological implants for damaged or diseased tissues and organs, and bioinformatics for determining which genes play a major role in health and disease. Biomedical engineering academic programs produce graduates with the ability to pursue successful careers in the biomedical device industry or to obtain advanced degrees leading to careers in biomedical engineering research, medicine, law or business. Biomedical engineering majors take courses in biology, anatomy, physics, chemistry, engineering, mathematics and medical product design and value life-long learning. Students learn to work effectively in interdisciplinary teams comprised of individuals with diverse social, cultural and technical backgrounds. Biomedical engineering is becoming increasingly important in imaging and image-guided research. Some examples of innovative ultrasound technology under development are ultrasound devices to accelerate the dissolution of blood clots, advanced surgical instruments with ultrasound guidance and ultrasound contrast agents for targeted drug delivery. Biomedical engineering is a great career choice for technically minded individuals who endeavor to work on applied problems that are medically relevant.

  15. Undergraduate research internships to support exploratory research in transportation engineering : project final report, Sept. 2008.

    Science.gov (United States)

    2008-09-01

    The Case Western Reserve University Department of Civil Engineering is in the process of expanding its teaching and research activities, Transportation Engineering as part of its initiative in the overall area of Infrastructure Performance and Reliab...

  16. 2007 Plant Metabolic Engineering Gordon Conference and Graduate Research Seminar

    Energy Technology Data Exchange (ETDEWEB)

    Erich Grotewold

    2008-09-15

    Plant Metabolic Engineering is an emerging field that integrates a diverse range of disciplines including plant genetics, genomics, biochemistry, chemistry and cell biology. The Gordon-Kenan Graduate Research Seminar (GRS) in Plant Metabolic Engineering was initiated to provide a unique opportunity for future researcher leaders to present their work in this field. It also creates an environment allowing for peer-review and critical assessment of work without the intimidation usually associated with the presence of senior investigators. The GRS immediately precedes the Plant Metabolic Engineering Gordon Research Conference and will be for and by graduate students and post-docs, with the assistance of the organizers listed.

  17. Natural Sciences and Engineering Research Council | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ca/index_eng.asp. International Research Initiative on Adaptation to Climate Change. The International Research Initiative on Adaptation to Climate Change aims to help vulnerable populations in Canada and in developing countries adapt to ...

  18. FOSER - Future of Software Engineering Research

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — The 2010 Report of the Presidents Council of Advisors on Science and Technology PCAST, entitled ?Designing a Digital Future: Federally Funded Research and...

  19. Artificial Sight Basic Research, Biomedical Engineering, and Clinical Advances

    CERN Document Server

    Humayun, Mark S; Chader, Gerald; Greenbaum, Elias

    2008-01-01

    Artificial sight is a frontier area of modern ophthalmology combining the multidisciplinary skills of surgical ophthalmology, biomedical engineering, biological physics, and psychophysical testing. Many scientific, engineering, and surgical challenges must be surmounted before widespread practical applications can be realized. The goal of Artificial Sight is to summarize the state-of-the-art research in this exciting area, and to describe some of the current approaches and initiatives that may help patients in a clinical setting. The Editors are active researchers in the fields of artificial sight, biomedical engineering and biological physics. They have received numerous professional awards and recognition for their work. The artificial sight team at the Doheny Eye Institute, led by Dr. Mark Humayun, is a world leader in this area of biomedical engineering and clinical research. Key Features Introduces and assesses the state of the art for a broad audience of biomedical engineers, biophysicists, and clinical...

  20. FY10 Engineering Innovations, Research and Technology Report

    Energy Technology Data Exchange (ETDEWEB)

    Lane, M A; Aceves, S M; Paulson, C N; Candy, J V; Bennett, C V; Carlisle, K; Chen, D C; White, D A; Bernier, J V; Puso, M A; Weisgraber, T H; Corey, B; Lin, J I; Wheeler, E K; Conway, A M; Kuntz, J D; Spadaccini, C M; Dehlinger, D A; Kotovsky, J; Nikolic, R; Mariella, R P; Foudray, A K; Tang, V; Guidry, B L; Ng, B M; Lemmond, T D; Chen, B Y; Meyers, C A; Houck, T L

    2011-01-11

    This report summarizes key research, development, and technology advancements in Lawrence Livermore National Laboratory's Engineering Directorate for FY2010. These efforts exemplify Engineering's nearly 60-year history of developing and applying the technology innovations needed for the Laboratory's national security missions, and embody Engineering's mission to ''Enable program success today and ensure the Laboratory's vitality tomorrow.'' Leading off the report is a section featuring compelling engineering innovations. These innovations range from advanced hydrogen storage that enables clean vehicles, to new nuclear material detection technologies, to a landmine detection system using ultra-wideband ground-penetrating radar. Many have been recognized with R&D Magazine's prestigious R&D 100 Award; all are examples of the forward-looking application of innovative engineering to pressing national problems and challenging customer requirements. Engineering's capability development strategy includes both fundamental research and technology development. Engineering research creates the competencies of the future where discovery-class groundwork is required. Our technology development (or reduction to practice) efforts enable many of the research breakthroughs across the Laboratory to translate from the world of basic research to the national security missions of the Laboratory. This portfolio approach produces new and advanced technological capabilities, and is a unique component of the value proposition of the Lawrence Livermore Laboratory. The balance of the report highlights this work in research and technology, organized into thematic technical areas: Computational Engineering; Micro/Nano-Devices and Structures; Measurement Technologies; Engineering Systems for Knowledge Discovery; and Energy Manipulation. Our investments in these areas serve not only known programmatic requirements of today and tomorrow, but

  1. The construction of social identity in newly recruited nuclear engineering staff: A longitudinal study

    International Nuclear Information System (INIS)

    Nguyen, Lynda; Murphy, Glen; Chang, Artemis

    2014-01-01

    This study examines the process by which newly recruited nuclear engineering and technical staff came to understand, define, think, feel and behave within a distinct group that has a direct contribution to the organization's overall emphasis on a culture of reliability and system safety. In the field of organizational behavior the interactive model of social identity formation has been recently proposed to explain the process by which the internalization of shared norms and values occurs, an element critical in identity formation. Using this rich model of organizational behavior we analyzed multiple sources of data from nine new hires over a period of three years. This was done from the time they were employed to investigate the construction of social identity by new entrants entering into a complex organizational setting reflected in the context of a nuclear facility. Informed by our data analyses, we found support for the interactive model of social identity development and report the unexpected finding that a newly appointed member's age and level of experience appears to influence the manner in which they adapt, and assimilate into their surroundings. This study represents an important contribution to the safety and reliability literature as it provides a rich insight into the way newly recruited employees enact the process by which their identities are formed and hence act, particularly under conditions of duress or significant organizational disruption in complex organizational settings. - Highlights: • We examined how newly recruited nuclear engineer staff develop their social identity. • The study empirically examined the interactive model of social identity formation. • Innovative research strategies were used to capture rich primary data for all case studies. • Age and experience moderated internalization route and the social identity formation process

  2. Development of a Taxonomy of Keywords for Engineering Education Research

    Science.gov (United States)

    Finelli, Cynthia J.; Borrego, Maura; Rasoulifar, Golnoosh

    2016-01-01

    The diversity of engineering education research provides an opportunity for cross-fertilisation of ideas and creativity, but it also can result in fragmentation of the field and duplication of effort. One solution is to establish a standardised taxonomy of engineering education terms to map the field and communicate and connect research…

  3. Case Study Research in Software Engineering Guidelines and Examples

    CERN Document Server

    Runeson, Per; Rainer, Austen; Regnell, Bjorn

    2012-01-01

    Based on their own experiences of in-depth case studies of software projects in international corporations, in this book the authors present detailed practical guidelines on the preparation, conduct, design and reporting of case studies of software engineering.  This is the first software engineering specific book on the case study research method.

  4. 32 CFR 22.310 - Statutes concerning certain research, development, and facilities construction grants.

    Science.gov (United States)

    2010-07-01

    ... higher education for the performance of research and development or for the construction of research or... for research and development, or of a grant for the construction of research or other facilities... research and development or for the construction of research or other facilities are to be awarded to...

  5. Development of large engineered cartilage constructs from a small population of cells.

    Science.gov (United States)

    Brenner, Jillian M; Kunz, Manuela; Tse, Man Yat; Winterborn, Andrew; Bardana, Davide D; Pang, Stephen C; Waldman, Stephen D

    2013-01-01

    Confronted with articular cartilage's limited capacity for self-repair, joint resurfacing techniques offer an attractive treatment for damaged or diseased tissue. Although tissue engineered cartilage constructs can be created, a substantial number of cells are required to generate sufficient quantities of tissue for the repair of large defects. As routine cell expansion methods tend to elicit negative effects on chondrocyte function, we have developed an approach to generate phenotypically stable, large-sized engineered constructs (≥3 cm(2) ) directly from a small amount of donor tissue or cells (as little as 20,000 cells to generate a 3 cm(2) tissue construct). Using rabbit donor tissue, the bioreactor-cultivated constructs were hyaline-like in appearance and possessed a biochemical composition similar to native articular cartilage. Longer bioreactor cultivation times resulted in increased matrix deposition and improved mechanical properties determined over a 4 week period. Additionally, as the anatomy of the joint will need to be taken in account to effectively resurface large affected areas, we have also explored the possibility of generating constructs matched to the shape and surface geometry of a defect site through the use of rapid-prototyped defect tissue culture molds. Similar hyaline-like tissue constructs were developed that also possessed a high degree of shape correlation to the original defect mold. Future studies will be aimed at determining the effectiveness of this approach to the repair of cartilage defects in an animal model and the creation of large-sized osteochondral constructs. Copyright © 2012 American Institute of Chemical Engineers (AIChE).

  6. Hempcrete Noise Barrier Wall for Highway Noise Insulation : Research & Construction

    OpenAIRE

    KC, Prabesh

    2016-01-01

    The purpose of this thesis was to study the possibility of Hempcrete or hemp-lime composite noise barrier walls in the highways and to construct the walls for the acoustic test according to the European Union Standards EN ISO 717-1 and ISO 10140-2 for air-borne sound insulation. The thesis was commissioned by the company Hemprefine Oy, and all the standard tests were performed in the HAMK-Ruukki Sheet Metal Centre in Hämeenlinna and the VTT Technical Research Centre of Finland Ltd in Espoo. ...

  7. Center for Alternative Fuels Research Program | College of Engineering &

    Science.gov (United States)

    Electrical Engineering Instructional Laboratories Student Resources Industrial & Manufacturing Engineering Industrial & Manufacturing Engineering Academic Programs Industrial & Manufacturing Engineering Major Industrial & Manufacturing Engineering Minor Industrial & Manufacturing Engineering

  8. Bone tissue engineering with human mesenchymal stem cell sheets constructed using magnetite nanoparticles and magnetic force.

    Science.gov (United States)

    Shimizu, Kazunori; Ito, Akira; Yoshida, Tatsuro; Yamada, Yoichi; Ueda, Minoru; Honda, Hiroyuki

    2007-08-01

    An in vitro reconstruction of three-dimensional (3D) tissues without the use of scaffolds may be an alternative strategy for tissue engineering. We have developed a novel tissue engineering strategy, termed magnetic force-based tissue engineering (Mag-TE), in which magnetite cationic liposomes (MCLs) with a positive charge at the liposomal surface, and magnetic force were used to construct 3D tissue without scaffolds. In this study, human mesenchymal stem cells (MSCs) magnetically labeled with MCLs were seeded onto an ultra-low attachment culture surface, and a magnet (4000 G) was placed on the reverse side. The MSCs formed multilayered sheet-like structures after a 24-h culture period. MSCs in the sheets constructed by Mag-TE maintained an in vitro ability to differentiate into osteoblasts, adipocytes, or chondrocytes after a 21-day culture period using each induction medium. Using an electromagnet, MSC sheets constructed by Mag-TE were harvested and transplanted into the bone defect in the crania of nude rats. Histological observation revealed that new bone surrounded by osteoblast-like cells was formed in the defect area 14 days after transplantation with MSC sheets, whereas no bone formation was observed in control rats without the transplant. These results indicated that Mag-TE could be used for the transplantation of MSC sheets using magnetite nanoparticles and magnetic force, providing novel methodology for bone tissue engineering.

  9. An Engineering Degree Does Not (Necessarily) an Engineer Make: Career Decision Making among Undergraduate Engineering Majors. Research Brief

    Science.gov (United States)

    Lichtenstein, Gary; Loshbaugh, Heidi G.; Claar, Brittany; Chen, Helen L.; Jackson, Kristyn; Sheppard, Sheri

    2009-01-01

    This paper explores the career-related decision making of seniors enrolled in undergraduate engineering programs at two nationally recognized institutions. This strand of the Academic Pathways Study (APS) research revealed that many engineering students were undecided about their career plans, even late into their senior years and that many were…

  10. Research on collaborative innovation mechanism of green construction supply chain based on united agency

    Science.gov (United States)

    Zhang, Min; He, Weiyi

    2018-06-01

    Under the guidance of principal-agent theory and modular theory, the collaborative innovation of green technology-based companies, design contractors and project builders based on united agency will provide direction for the development of green construction supply chain in the future. After analyzing the existing independent agencies, this paper proposes the industry-university-research bilateral collaborative innovation network architecture and modularization with the innovative function of engineering design in the context of non-standard transformation interfaces, analyzes the innovation responsibility center, and gives some countermeasures and suggestions to promote the performance of bilateral cooperative innovation network.

  11. Thermometric consideration for RF and microwave research in food engineering.

    Science.gov (United States)

    Ofoli, R Y

    1986-01-01

    A review of thermometric methods for the processing of food materials at RF and microwave frequencies is presented. Some areas of needed food engineering research are discussed, as well as factors of importance in the selection of temperature monitoring systems.

  12. 76 FR 37085 - Applications for New Awards; Rehabilitation Engineering Research Centers (RERCs)

    Science.gov (United States)

    2011-06-24

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Rehabilitation Engineering Research Centers...)--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research... (Rehabilitation Act). Rehabilitation Engineering Research Centers Program (RERCs) The purpose of the RERC program...

  13. Energy engineering: Student-researcher collaboration

    DEFF Research Database (Denmark)

    Leban, Krisztina Monika; Ritchie, Ewen; Beckowska, Patrycja Maria

    2013-01-01

    This article reports on cooperation methods between researchers and students at different levels. Levels included in this work are BSc, MSc and PhD student levels. At Aalborg University, Department of Energy Technology education and research are closely linked. The relationship between student...

  14. Three-Dimensional Engineered Bone–Ligament–Bone Constructs for Anterior Cruciate Ligament Replacement

    Science.gov (United States)

    Ma, Jinjin; Smietana, Michael J.; Kostrominova, Tatiana Y.; Wojtys, Edward M.; Larkin, Lisa M.

    2012-01-01

    The anterior cruciate ligament (ACL), a major stabilizer of the knee, is commonly injured. Because of its intrinsic poor healing ability, a torn ACL is usually reconstructed by a graft. We developed a multi-phasic, or bone–ligament–bone, tissue-engineered construct for ACL grafts using bone marrow stromal cells and sheep as a model system. After 6 months in vivo, the constructs increased in cross section and exhibited a well-organized microstructure, native bone integration, a functional enthesis, vascularization, innervation, increased collagen content, and structural alignment. The constructs increased in stiffness to 52% of the tangent modulus and 95% of the geometric stiffness of native ACL. The viscoelastic response of the explants was virtually indistinguishable from that of adult ACL. These results suggest that our constructs after implantation can obtain physiologically relevant structural and functional characteristics comparable to those of adult ACL. They present a viable option for ACL replacement. PMID:21902608

  15. Summaries of FY 1995 engineering research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The individual engineering project summaries follow the program overview. The summaries are ordered alphabetically by name of institution and so the table of contents lists all the institutions at which projects were sponsored in fiscal year 1995. Each project entry begins with an institutional-departmental heading. The names of investigators are listed immediately below the title. The funding level for fiscal year 1995 appears to the right of title; it is followed by the budget activity number. These numbers categorize the projects for budgetary purposes and the categories are described in the budget number index. A separate index of Principal Investigators includes phone number, fax number and e-mail address, where available. The fiscal year in which either the project began or was renewed and the anticipated duration in years are indicated respectively by the first two and last digits of the sequence directly below the budget activity number. The summary description of the project completes the entry.

  16. Growth Factor Stimulation Improves the Structure and Properties of Scaffold-Free Engineered Auricular Cartilage Constructs

    Science.gov (United States)

    Rosa, Renata G.; Joazeiro, Paulo P.; Bianco, Juares; Kunz, Manuela; Weber, Joanna F.; Waldman, Stephen D.

    2014-01-01

    The reconstruction of the external ear to correct congenital deformities or repair following trauma remains a significant challenge in reconstructive surgery. Previously, we have developed a novel approach to create scaffold-free, tissue engineering elastic cartilage constructs directly from a small population of donor cells. Although the developed constructs appeared to adopt the structural appearance of native auricular cartilage, the constructs displayed limited expression and poor localization of elastin. In the present study, the effect of growth factor supplementation (insulin, IGF-1, or TGF-β1) was investigated to stimulate elastogenesis as well as to improve overall tissue formation. Using rabbit auricular chondrocytes, bioreactor-cultivated constructs supplemented with either insulin or IGF-1 displayed increased deposition of cartilaginous ECM, improved mechanical properties, and thicknesses comparable to native auricular cartilage after 4 weeks of growth. Similarly, growth factor supplementation resulted in increased expression and improved localization of elastin, primarily restricted within the cartilaginous region of the tissue construct. Additional studies were conducted to determine whether scaffold-free engineered auricular cartilage constructs could be developed in the 3D shape of the external ear. Isolated auricular chondrocytes were grown in rapid-prototyped tissue culture molds with additional insulin or IGF-1 supplementation during bioreactor cultivation. Using this approach, the developed tissue constructs were flexible and had a 3D shape in very good agreement to the culture mold (average error tissue structure and 3D shape of the external ear, future studies will be aimed assessing potential changes in construct shape and properties after subcutaneous implantation. PMID:25126941

  17. Research directions in computer engineering. Report of a workshop

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, H

    1982-09-01

    The results of a workshop held in November 1981 in Washington, DC, to outline research directions for computer engineering are reported upon. The purpose of the workshop was to provide guidance to government research funding agencies, as well as to universities and industry, as to the directions which computer engineering research should take for the next five to ten years. A select group of computer engineers was assembled, drawn from all over the United States and with expertise in virtually every aspect of today's computer technology. Industrial organisations and universities were represented in roughly equal numbers. The panel proceeded to provide a sharper definition of computer engineering than had been in popular use previously, to identify the social and national needs which provide the basis for encouraging research, to probe for obstacles to research and seek means of overcoming them and to delineate high-priority areas in which computer engineering research should be fostered. These included experimental software engineering, architectures in support of programming style, computer graphics, pattern recognition. VLSI design tools, machine intelligence, programmable automation, architectures for speech and signal processing, computer architecture and robotics. 13 references.

  18. Facile construction of a random protein domain insertion library using an engineered transposon.

    Science.gov (United States)

    Shah, Vandan; Pierre, Brennal; Kim, Jin Ryoun

    2013-01-15

    Insertional fusion between multiple protein domains represents a novel means of creating integrated functionalities. Currently, there is no robust guideline for selection of insertion sites ensuring the desired functional outcome of insertional fusion. Therefore, construction and testing of random domain insertion libraries, in which a host protein domain is randomly inserted into a guest protein domain, significantly benefit extensive exploration of sequence spaces for insertion sites. Short peptide residues are usually introduced between protein domains to alleviate structural conflicts, and the interdomain linker residues may affect the functional outcome of protein insertion complexes. Unfortunately, optimal control of interdomain linker residues is not always available in conventional methods used to construct random domain insertion libraries. Moreover, most conventional methods employ blunt-end rather than sticky-end ligation between host and guest DNA fragments, thus lowering library construction efficiency. Here, we report the facile construction of random domain insertion libraries using an engineered transposon. We show that random domain insertion with optimal control of interdomain linker residues was possible with our engineered transposon-based method. In addition, our method employs sticky-end rather than blunt-end ligation between host and guest DNA fragments, thus allowing for facile construction of relatively large sized libraries. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. Research and Exploration for Operational Research Education in Industry and Engineering Subject

    Science.gov (United States)

    Wu, Yu-hua; Wang, Feng-ming; Du, Gang

    2007-01-01

    On the basic of exploring the relationship of industry engineering and operational research technique, the thesis analyzes the location and utility of the operational research education in the whole industry engineering subject education. It brings forward the system design about operational research and relative class among industry engineering…

  20. Hybrid printing of mechanically and biologically improved constructs for cartilage tissue engineering applications

    International Nuclear Information System (INIS)

    Xu Tao; Binder, Kyle W; Albanna, Mohammad Z; Dice, Dennis; Zhao Weixin; Yoo, James J; Atala, Anthony

    2013-01-01

    Bioprinting is an emerging technique used to fabricate viable, 3D tissue constructs through the precise deposition of cells and hydrogels in a layer-by-layer fashion. Despite the ability to mimic the native properties of tissue, printed 3D constructs that are composed of naturally-derived biomaterials still lack structural integrity and adequate mechanical properties for use in vivo, thus limiting their development for use in load-bearing tissue engineering applications, such as cartilage. Fabrication of viable constructs using a novel multi-head deposition system provides the ability to combine synthetic polymers, which have higher mechanical strength than natural materials, with the favorable environment for cell growth provided by traditional naturally-derived hydrogels. However, the complexity and high cost associated with constructing the required robotic system hamper the widespread application of this approach. Moreover, the scaffolds fabricated by these robotic systems often lack flexibility, which further restrict their applications. To address these limitations, advanced fabrication techniques are necessary to generate complex constructs with controlled architectures and adequate mechanical properties. In this study, we describe the construction of a hybrid inkjet printing/electrospinning system that can be used to fabricate viable tissues for cartilage tissue engineering applications. Electrospinning of polycaprolactone fibers was alternated with inkjet printing of rabbit elastic chondrocytes suspended in a fibrin–collagen hydrogel in order to fabricate a five-layer tissue construct of 1 mm thickness. The chondrocytes survived within the printed hybrid construct with more than 80% viability one week after printing. In addition, the cells proliferated and maintained their basic biological properties within the printed layered constructs. Furthermore, the fabricated constructs formed cartilage-like tissues both in vitro and in vivo as evidenced by the

  1. Review of research on simulation engineering in FY2007

    International Nuclear Information System (INIS)

    2009-02-01

    Research on simulation engineering for nuclear applications, based on the plan for meeting the mid-term goal of the Japan Atomic Energy Agency', has been performed at Center for Computational Science and e-Systems, Japan Atomic Energy Agency (CCSE/JAEA). CCSE established the committee consisting outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the result of the evaluation by the committee on the research on simulation engineering performed at CCSE/JAEA in FY2007. (author)

  2. Review of research on simulation engineering in FY2008

    International Nuclear Information System (INIS)

    2010-02-01

    Research on simulation engineering for nuclear applications, based on 'the plan for meeting the mid-term goal of the Japan Atomic Energy Agency', has been performed at Center for Computational Science and e-Systems, Japan Atomic Energy Agency (CCSE/JAEA). CCSE established the committee consisting outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes the result of the evaluation by the committee on the research on simulation engineering performed at CCSE/JAEA in FY2008. (author)

  3. Applying system engineering methods to site characterization research for nuclear waste repositories

    International Nuclear Information System (INIS)

    Woods, T.W.

    1985-01-01

    Nuclear research and engineering projects can benefit from the use of system engineering methods. This paper is brief overview illustrating how system engineering methods could be applied in structuring a site characterization effort for a candidate nuclear waste repository. System engineering is simply an orderly process that has been widely used to transform a recognized need into a fully defined system. Such a system may be physical or abstract, natural or man-made, hardware or procedural, as is appropriate to the system's need or objective. It is a way of mentally visualizing all the constituent elements and their relationships necessary to fulfill a need, and doing so compliant with all constraining requirements attendant to that need. Such a system approach provides completeness, order, clarity, and direction. Admittedly, system engineering can be burdensome and inappropriate for those project objectives having simple and familiar solutions that are easily held and controlled mentally. However, some type of documented and structured approach is needed for those objectives that dictate extensive, unique, or complex programs, and/or creation of state-of-the-art machines and facilities. System engineering methods have been used extensively and successfully in these cases. The scientific methods has served well in ordering countless technical undertakings that address a specific question. Similarly, conventional construction and engineering job methods will continue to be quite adequate to organize routine building projects. Nuclear waste repository site characterization projects involve multiple complex research questions and regulatory requirements that interface with each other and with advanced engineering and subsurface construction techniques. There is little doubt that system engineering is an appropriate orchestrating process to structure such diverse elements into a cohesive, well defied project

  4. DIRECTIONS FOR FUTURE CONSTRUCTION SUPPLY CHAIN MANAGEMENT RESEARCH IN NEW ZEALAND: A REAL OPTIONS PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Tran, Van

    2012-04-01

    Full Text Available Real Options (RO has been a universally accepted concept in a number of major industries. However, its use in the construction supply chain management (CSCM sector has been limited. Some rare supply chain management RO studies have shown a number of limitations. First, there is a lack of a rigorous theoretical RO framework pertaining specifically to CSCM. All such supply chain management RO studies are based off RO theories or models developed for other sectors (engineering, infrastructure, natural resources. And second, attempts to extend real option to wider uses in CSCM seem premature at the present. This paper reviews all recent literature pertaining to real options and real options applied specifically to the construction supply chain management area. The study proposes a research programme pertaining to CSCM in New Zealand in order to enhance the current understanding of RO in this area and in the process develop a comprehensive theory for the RO application in New Zealand CSCM.

  5. [Purveyors of technology: provincial engineers and the construction of road infrastructure in Minas Gerais].

    Science.gov (United States)

    Barbosa, Lidiany Silva

    2011-01-01

    The article analyzes the role played by engineers in the construction of road infrastructure in Minas Gerais between the 1840s and 1880s. Building and providing regular maintenance for roads and bridges was a task carried out by the Minas Gerais provincial government, which since the 1830s had a specific agency assigned to designing, building, and maintaining public communication routes. Engineers were part of the agency from its inception, playing a significant role in designing projects and in the actual execution of certain works. The current study is grounded in administrative documentation in which the details of work progress are reported to the provincial government. The gathered records provide technical, administrative, and financial information, along with data on labor power and the agents engaged in construction works.

  6. An analysis of extended entity relationship constructs extraction in database reverse engineering approaches

    International Nuclear Information System (INIS)

    Jilani, M.A.; Aziz, A.; Hussain, T.

    2008-01-01

    Database reverse Engineering is technique used for transforming relational schema into a conceptual schema for finding and fixing design flaw for maintaining and re-engineering database systems for the integration of database system with another and migration of a database system from one platform to another. We studied the approaches from year 1993 to 2006 to find out which EER construct cannot be retrieved by most of the DBRE approaches so that they can be retrieved in the future. For each EER construct that can be retrieved by using a given DBRE approach. We show whether they are retrieved without user involvement (automatically). Partial user involvement (semi-automatically) or full user involvement (manually). We also discuss the relevant advantages and limitations of each DBRE technique considered in this paper. (author)

  7. The development of the collagen fibre network in tissue-engineered cartilage constructs in vivo. Engineered cartilage reorganises fibre network

    Directory of Open Access Journals (Sweden)

    H Paetzold

    2012-04-01

    Full Text Available For long term durability of tissue-engineered cartilage implanted in vivo, the development of the collagen fibre network orientation is essential as well as the distribution of collagen, since expanded chondrocytes are known to synthesise collagen type I. Typically, these properties differ strongly between native and tissue-engineered cartilage. Nonetheless, the clinical results of a pilot study with implanted tissue-engineered cartilage in pigs were surprisingly good. The purpose of this study was therefore to analyse if the structure and composition of the artificial cartilage tissue changes in the first 52 weeks after implantation. Thus, collagen network orientation and collagen type distribution in tissue-engineered cartilage-carrier-constructs implanted in the knee joints of Göttinger minipigs for 2, 26 or 52 weeks have been further investigated by processing digitised microscopy images of histological sections. The comparison to native cartilage demonstrated that fibre orientation over the cartilage depth has a clear tendency towards native cartilage with increasing time of implantation. After 2 weeks, the collagen fibres of the superficial zone were oriented parallel to the articular surface with little anisotropy present in the middle and deep zones. Overall, fibre orientation and collagen distribution within the implants were less homogenous than in native cartilage tissue. Despite a relatively low number of specimens, the consistent observation of a continuous approximation to native tissue is very promising and suggests that it may not be necessary to engineer the perfect tissue for implantation but rather to provide an intermediate solution to help the body to heal itself.

  8. Review of research on simulation engineering in FY2009

    International Nuclear Information System (INIS)

    2011-03-01

    Research on simulation engineering for nuclear applications, based on 'the plan for meeting the mid-term goal of the Japan Atomic Energy Agency', has been performed at Center for Computational Science and e-Systems, Japan Atomic Energy Agency (CCSE/JAEA). CCSE established the committee consisting outside experts and authorities which does research evaluation and advices for the assistance of the research and development. This report summarizes results of the evaluation by the committee on the followings. (1) Research and development on simulation engineering performed at CCSE/JAEA in FY2009. (2) Research and development on simulation engineering performed at CCSE/JAEA in the period of the midterm plan (October 1st, 2005 - March 31st, 2010). (author)

  9. Barriers to the Uptake of Concurrent Engineering in the Nigerian Construction Industry

    Directory of Open Access Journals (Sweden)

    Nathaniel Anny Aniekwu

    2012-12-01

    engineering and also to compute the Kendall’s coefficient of concordance, which assess the levels of agreement among the judges on the consistency of the rankings. A Kendall’s coefficient of concordance of W=0.57365 was recorded. A lack of awareness emerged as the most important barrier against the integration of this concept into the Nigerian construction industry. The top five variables are all human factors that can be ameliorated by proper education.

  10. Evolutionary, Unconscious Design Support for the Architectural, Engineering and Construction Industry

    OpenAIRE

    Van de Ruitenbeek, H.K.M.

    2012-01-01

    The Architecture, Engineering and Construction (AEC) industry is a complex system in which carpenters, structural designers, architects, modellers, cost estimators, planners, politicians and many others act apart together in project-specific virtual enterprises. There is a large amount of actors, an overwhelming number of ongoing processes, distributed, decentralised organisations and a variety of projects. This complicates efficient communication and supply chain integration which, according...

  11. An Analytical Reverse Engineering of IELTS Listening Tasks for a Construct Model

    OpenAIRE

    Masood Khalili Sabet; Hamid Reza Babaee Bormanaki

    2017-01-01

    The study reported here was concerned with the issue of reverse engineering of language test items as it relates to the identification of the language constructs underlying listening tasks of LELTS test. In this regard, the IELTS examination papers, from IELTS 1 to IELTS 10 were compiled as a corpus for the analysis. Tasks were analyzed using a taxonomic frame work adopted from Moore, Morton and price (2012), that was originally adapted from Weir and Urquhart (1998), with a focus on two dimen...

  12. Chemical Engineering Division research highlights, 1977

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-08-01

    Separate abstracts are included for sections with information on lithium/metal sulfide batteries; electrochemical energy development; advanced fuel cell development; utilization of coal; magnetohydrodynamics technology; LMFBR and GCFR support work; fuel cycle studies; fusion reactor research; solar energy development; and basic energy science.

  13. Chemical Engineering Division research highlights, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Burris, L.; Webster, D. S.; Barney, D. L.; Cafasso, F. A.; Steindler, M. J.

    1980-06-01

    In 1979, CEN conducted research and development in the following areas: (1) high-temperature, rechargeable lithium/iron sulfide batteries for electric vehicles and electric utility load leveling; (2) ambient-temperature batteries - improved lead-acid, nickel/zinc, and nickel/iron - for electric vehicles; (3) molten carbonate fuel cells for use by electric utilities; (4) coal technology - mainly fluidized-bed combustion of coal in the presence of SO/sub 2/ sorbent of limestone; (5) heat- and seed- recovery technology for open-cycle magnetohydrodynamic systems; (6) solar energy collectors and thermal energy storage; (7) fast breeder reactor chemistry research - chemical support of reactor safety studies, chemistry of irradiated fuels, and sodium technology; (8) fuel cycle technology - reprocessing of nuclear fuels, management of nuclear wastes, geologic migration studies, and proof-of-breeding studies for the Light Water Breeder Reactor; (9) magnetic fusion research - lithium processing technology and materials research; and (10) basic energy sciences - homogeneous catalysis, thermodynamics of inorganic and organic materials, environmental chemistry, electrochemistry, and physical properties of salt vapors. Separate abstracts were prepared for each of these areas.

  14. Global Journal of Engineering Research: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  15. Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends.

    Science.gov (United States)

    Oliveira, Sara M; Reis, Rui L; Mano, João F

    2015-11-01

    The design of 3D constructs with adequate properties to instruct and guide cells both in vitro and in vivo is one of the major focuses of tissue engineering. Successful tissue regeneration depends on the favorable crosstalk between the supporting structure, the cells and the host tissue so that a balanced matrix production and degradation are achieved. Herein, the major occurring events and players in normal and regenerative tissue are overviewed. These have been inspiring the selection or synthesis of instructive cues to include into the 3D constructs. We further highlight the importance of a multiscale perception of the range of features that can be included on the biomimetic structures. Lastly, we focus on the current and developing tissue-engineering approaches for the preparation of such 3D constructs: top-down, bottom-up and integrative. Bottom-up and integrative approaches present a higher potential for the design of tissue engineering devices with multiscale features and higher biochemical control than top-down strategies, and are the main focus of this review. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Proteomic profiling of tissue-engineered blood vessel walls constructed by adipose-derived stem cells.

    Science.gov (United States)

    Wang, Chen; Guo, Fangfang; Zhou, Heng; Zhang, Yun; Xiao, Zhigang; Cui, Lei

    2013-02-01

    Adipose-derived stem cells (ASCs) can differentiate into smooth muscle cells and have been engineered into elastic small diameter blood vessel walls in vitro. However, the mechanisms involved in the development of three-dimensional (3D) vascular tissue remain poorly understood. The present study analyzed protein expression profiles of engineered blood vessel walls constructed by human ASCs using methods of two-dimensional gel electrophoresis (2DE) and mass spectrometry (MS). These results were compared to normal arterial walls. A total of 1701±15 and 1265±26 protein spots from normal and engineered blood vessel wall extractions were detected by 2DE, respectively. A total of 20 spots with at least 2.0-fold changes in expression were identified, and 38 differently expressed proteins were identified by 2D electrophoresis and ion trap MS. These proteins were classified into seven functional categories: cellular organization, energy, signaling pathway, enzyme, anchored protein, cell apoptosis/defense, and others. These results demonstrated that 2DE, followed by ion trap MS, could be successfully utilized to characterize the proteome of vascular tissue, including tissue-engineered vessels. The method could also be employed to achieve a better understanding of differentiated smooth muscle protein expression in vitro. These results provide a basis for comparative studies of protein expression in vascular smooth muscles of different origin and could provide a better understanding of the mechanisms of action needed for constructing blood vessels that exhibit properties consistent with normal blood vessels.

  17. THE CONSTRUCTION OF THE RESEARCH PROBLEM AND ITS DISCUSSION

    Directory of Open Access Journals (Sweden)

    Eva Pasek de Pinto

    2008-04-01

    Full Text Available Language has different functions. One of them, the communication, is fundamental for the investigation, because the textualization of its process and results is the base of the diffusion of the advance and increase of the scientific knowledge. However, most students - and those who are not already so - present difficulties in using references, in breaks in cohesion, or in logical and argumentative coherence. Such difficulties limit the generation of texts, as they constitute an obstacle to translate written ideas into an argumentative discourse, typical of science and research. The latter requires the argued presentation of an idea, whose perception, description and obvious reasons make up the problem that is wanted to know, to explain, to verify, to understand or to interpret. Therefore, this short space / time has the purpose of reflecting on the discursive construction of the problem of an inquiry. Its importance lies precisely in the disadvantages of its configuration. In this sense, the reflection is developed from a vision of language and communication; The argumentative discourse and the types of reasoning involved in order to fulfill certain guidelines that underlie the construction of the problem of inquiry and its approach in terms of a positivist-quantitative and / or qualitative study.

  18. Impacting Society through Engineering Design Research

    DEFF Research Database (Denmark)

    Howard, Thomas J.

    2011-01-01

    Following the recent ICED11 conference in Copenhagen, Thomas Howard, ICED11 Assistant Chair and Ass. Professor at DTU has written a reflection on design research and design practice, suggesting that in addition to benefiting society through the improved understanding of methods of and approaches...... to design, the academic design community should through design practice produce empowering products which address societal needs unbound by the necessity for profit....

  19. Engineering education research: Impacts of an international network of female engineers on the persistence of Liberian undergraduate women studying engineering

    Science.gov (United States)

    Rimer, Sara; Reddivari, Sahithya; Cotel, Aline

    2015-11-01

    As international efforts to educate and empower women continue to rise, engineering educators are in a unique position to be a part of these efforts by encouraging and supporting women across the world at the university level through STEM education and outreach. For the past two years, the University of Michigan has been a part of a grassroots effort to encourage and support the persistence of engineering female students at University of Liberia. This effort has led to the implementation of a leadership camp this past August for Liberian engineering undergraduate women, meant to: (i) to empower engineering students with the skills, support, and inspiration necessary to become successful and well-rounded engineering professionals in a global engineering market; and (ii) to strengthen the community of Liberian female engineers by building cross-cultural partnerships among students resulting in a international network of women engineers. This session will present qualitative research findings on the impact of this grassroots effort on Liberian female students? persistence in engineering, and the future directions of this work.

  20. An Update to Space Biomedical Research: Tissue Engineering in Microgravity Bioreactors

    Directory of Open Access Journals (Sweden)

    Abolfazl Barzegari

    2012-03-01

    Full Text Available Introduction: The severe need for constructing replacement tissues in organ transplantation has necessitated the development of tissue engineering approaches and bioreactors that can bring these approaches to reality. The inherent limitations of conventional bioreactors in generating realistic tissue constructs led to the devise of the microgravity tissue engineering that uses Rotating Wall Vessel (RWV bioreactors initially developed by NASA. Methods: In this review article, we intend to highlight some major advances and accomplishments in the rapidly-growing field of tissue engineering that could not be achieved without using microgravity. Results: Research is now focused on assembly of 3 dimensional (3D tissue fragments from various cell types in human body such as chondrocytes, osteoblasts, embryonic and mesenchymal stem cells, hepatocytes and pancreas islet cells. Hepatocytes cultured under microgravity are now being used in extracorporeal bioartificial liver devices. Tissue constructs can be used not only in organ replacement therapy, but also in pharmaco-toxicology and food safety assessment. 3D models of various cancers may be used in studying cancer development and biology or in high-throughput screening of anticancer drug candidates. Finally, 3D heterogeneous assemblies from cancer/immune cells provide models for immunotherapy of cancer. Conclusion: Tissue engineering in (simulated microgravity has been one of the stunning impacts of space research on biomedical sciences and their applications on earth.

  1. Research into command, control, and communications in space construction

    Science.gov (United States)

    Davis, Randal

    1990-01-01

    Coordinating and controlling large numbers of autonomous or semi-autonomous robot elements in a space construction activity will present problems that are very different from most command and control problems encountered in the space business. As part of our research into the feasibility of robot constructors in space, the CSC Operations Group is examining a variety of command, control, and communications (C3) issues. Two major questions being asked are: can we apply C3 techniques and technologies already developed for use in space; and are there suitable terrestrial solutions for extraterrestrial C3 problems? An overview of the control architectures, command strategies, and communications technologies that we are examining is provided and plans for simulations and demonstrations of our concepts are described.

  2. Research and development of turbofan engine for supersonic aircraft. Choonsokukiyo turbofan engine no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Yashima, S [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1992-01-01

    This paper described the researched results of the demonstrator of a turbofan engine for supersonic aircraft (IHI-17). A turbofan engine with an afterburner was experimentally fabricated and various engine tests have been carried out since 1988. Although the engine size is small, the fighter engine specifications were applied to its design and the prior or simultaneous research on each component was carried out. As a result, the system integration technique by which an engine was assembled by integrating each component could be established. New materials and new manufacturing techniques such as turbine blades of single crystal, turbine disks of powder metallurgy and deep chemical milling for a duct were developed to use for the long term engine test and the prospect to commercialization could be obtained. The following techniques have been established and the results satisfying target specifications could be achieved: the three dimensional aerodynamic design of compressor and turbine, the adoption of air blast fuel atomizer to suppress the smoke generation, an afterburner of spray bar system and the mounting type FADEC (full authority digital electronic control) to control the engine with the afterburner. 4 refs., 15 figs., 4 tabs.

  3. Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering

    Science.gov (United States)

    Zakhem, Elie; Raghavan, Shreya; Gilmont, Robert R; Bitar, Khalil N

    2012-01-01

    Intestinal tissue engineering is an emerging field due to a growing demand for intestinal lengthening and replacement procedures secondary to massive resections of the bowel. Here, we demonstrate the potential use of a chitosan/collagen scaffold as a 3D matrix to support the bioengineered circular muscle constructs maintain their physiological functionality. We investigated the biocompatibility of chitosan by growing rabbit colonic circular smooth muscle cells (RCSMCs) on chitosan-coated plates. The cells maintained their spindle-like morphology and preserved their smooth muscle phenotypic markers. We manufactured tubular scaffolds with central openings composed of chitosan and collagen in a 1:1 ratio. Concentrically-aligned 3D circular muscle constructs were bioengineered using fibrin-based hydrogel seeded with RCSMCs. The constructs were placed around the scaffold for 2 weeks, after which they were taken off and tested for their physiological functionality. The muscle constructs contracted in response to Acetylcholine (Ach) and potassium chloride (KCl) and they relaxed in response to vasoactive intestinal peptide (VIP). These results demonstrate that chitosan is a biomaterial possibly suitable for intestinal tissue engineering applications. PMID:22483012

  4. Application of 3D CADDS model to design and engineering for constructability improvement

    International Nuclear Information System (INIS)

    Cho, U.Y.; Park, C.C.; Choy, E.

    1998-01-01

    The use of three dimensional (3D) computer-aided design and drafting system (CADDS) model along with the associated information management system in engineering phases of large projects is well established and yielding significant improvements in project cost, schedule and quality. The information contained in these models can also be utilized in plant construction site for construction schedule review, installation procedure review, interference check, and visual communication tool to the utility owner when the visual and spatial information contained in the 3D models is integrated with other plant information. This paper will describe the application of 3D models and the associated databases in the construction process of CANDU HWR heavy water reactors. Some examples on the use of 3D CADD models in CANDU projects will be presented

  5. Various aspects of research of the SI engine with an additional expansion process

    Directory of Open Access Journals (Sweden)

    Noga Marcin

    2017-01-01

    Full Text Available The paper presents an analysis of the results of the both experimental results and theoretical works on the SI engine with additional expansion of exhaust gases, also known as five-stroke engine. The engine like this was constructed at Cracow University of Technology as a retrofitted in-line four cylinder engine in which outer cylinders (1st and 4th work as fired cylinders and inner cylinders (2nd and 3rd work as volume for the additional expansion. The aim of development of such an engine is to gain higher energy recovery ratio of the combusted fuel through the second expansion of exhaust in a separate cylinder. The operating parameters of the engine in various versions were analyzed: as naturally aspirated, supercharged using a turbocharger with a waste-gate valve and a turbocharger with variable nozzle turbine. Selected results of the indicating measurements of the engine with special emphasis on the indicated thermal efficiency were presented. The results pointed out the directions of further optimization of the engine. These results are all the more important, because according to the author’s knowledge, the research on the real object of this type are carried out in only one science center in the world besides Cracow University of Technology.

  6. Not so Global: A Bibliometric Look at Engineering Education Research

    Science.gov (United States)

    Williams, Bill; Wankat, Phillip C.; Neto, Pedro

    2018-01-01

    It has been suggested that Engineering Education Research (EER) is going global. If this were the case we would assume that the research of EER scholars in different parts of the globe would be informed by literature describing prior work within and beyond their home country/region. The authors set out to test this hypothesis by applying citation…

  7. Developing Research Skills for Civil Engineers: A Library Contribution.

    Science.gov (United States)

    Bruce, C. S.; Brameld, G. H.

    1990-01-01

    A library instruction program has been instituted in civil engineering at the Queensland University of Technology (Australia) in an effort to improve the research skills of fourth year students working on research projects. Students with extended library instruction were found to have better information-seeking behavior than others. (Author/MSE)

  8. DATA MANAGEMENT PLANNING IN ENGINEERING DESIGN AND MANUFACTURING RESEARCH

    DEFF Research Database (Denmark)

    Darlington, Mansur; Howard, Thomas J.; Ball, Alex

    2011-01-01

    of research data and of the barriers to and opportunities for their re-use. The work reported here characterizes engineering design and manufacture research data and explores the context of their development and current management. Insights from the work have resulted in the authors proposing a number of new...

  9. Office of Research Support | College of Engineering & Applied Science

    Science.gov (United States)

    Professor and Associate Dean for Research College of Engineering and Applied Sciences Director, Center for Academics Admission Student Life Research Schools & Colleges Libraries Athletics Centers & ; Applied Science Powerful Ideas. Proven Results. Search for: Go This site All UWM Search Site Menu Skip to

  10. Exploration on the reform of the science and engineering experiment teaching based on the combination with teaching and scientific research

    Science.gov (United States)

    Song, Peng

    2017-08-01

    The existing problems of the experiment education in colleges and universities are analyzed. Take the science and engineering specialty as example, the idea of the combination with teaching and scientific research is discussed. The key problems are how the scientific research and scientific research achievements are used effectively in the experiment education, how to effectively use scientific research laboratories and scientific researchers. Then, a specialty experiment education system is established which is good for the teaching in accordance of all students' aptitude. The research in this paper can give the construction of the experiment teaching methods and the experiment system reform for the science and engineering specialties in colleges and universities.

  11. A novel bioprinting method and system for forming hybrid tissue engineering constructs.

    Science.gov (United States)

    Shanjani, Y; Pan, C C; Elomaa, L; Yang, Y

    2015-12-18

    Three dimensional (3D) bioprinting is a promising approach to form tissue engineering constructs (TECs) via positioning biomaterials, growth factors, and cells with controlled spatial distribution due to its layer-by-layer manufacturing nature. Hybrid TECs composed of relatively rigid porous scaffolds for structural and mechanical integrity and soft hydrogels for cell- and growth factor-loading have a tremendous potential to tissue regeneration under mechanical loading. However, despite excessive progress in the field, the current 3D bioprinting techniques and systems fall short in integration of such soft and rigid multifunctional components. Here we present a novel 3D hybrid bioprinting technology (Hybprinter) and its capability enabling integration of soft and rigid components for TECs. Hybprinter employs digital light processing-based stereolithography (DLP-SLA) and molten material extrusion techniques for soft and rigid materials, respectively. In this study, poly-ethylene glycol diacrylate (PEGDA) and poly-(ε-caprolactone) (PCL) were used as a model material for soft hydrogel and rigid scaffold, respectively. It was shown that geometrical accuracy, swelling ratio and mechanical properties of the hydrogel component can be tailored by DLP-SLA module. We have demonstrated the printability of variety of complex hybrid construct designs using Hybprinter technology and characterized the mechanical properties and functionality of such constructs. The compressive mechanical stiffness of a hybrid construct (90% hydrogel) was significantly higher than hydrogel itself (∼6 MPa versus 100 kPa). In addition, viability of cells incorporated within the bioprinted hybrid constructs was determined approximately 90%. Furthermore, a functionality of a hybrid construct composed of porous scaffold with an embedded hydrogel conduit was characterized for vascularized tissue engineering applications. High material diffusion and high cell viability in about 2.5 mm distance

  12. Role of the chemical engineering technician in applied research related to tritium separation from aqueous effluents

    International Nuclear Information System (INIS)

    Nelson, S.D.

    1978-01-01

    Applied research and development activities related to the removal of tritium from aqueous effluent streams have presented broad opportunities to the chemical engineering technician for professional growth. Technician job activities involve operating complex analytical instrumentation and constructing, maintaining, and operating experimental electrolysis apparatus. The technician is a member of a professional team including scientific, engineering, and other technical personnel and as such is expected to exercise creative thought. Proximity of a large university and availability of formalized ''in house'' training courses provide incentives for technicians to broaden their academic base concurrent with their work involvement

  13. Engineering research, development and technology: Thrust area report FY 91

    International Nuclear Information System (INIS)

    1991-01-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence, Livermore National Laboratory (LLNL) is to develop the technical staff and the technology needed to support current and future LLNL programs. To accomplish this mission, the Engineering Research, Development, and Technology Program has two important goals: (1) to identify key technologies and (2) conduct high quality work to enhance our capabilities in these key technologies. To help focus our efforts, we identify technology thrust areas and select technical leaders for each area. The thrust areas are integrated engineering activities and, rather than being based on individual disciplines, they are staffed by personnel from Electronics Engineering, Mechanical Engineering, and other LLNL organizations, as appropriate. The thrust area leaders are expected to establish strong links to LLNL program leaders and to industry; to use outside and inside experts to review the quality and direction of the work; to use university contacts to supplement and complement their efforts; and to be certain that we are not duplicating the work of others. The thrust area leader is also responsible for carrying out the work that follows from the Engineering Research, Development, and Technology Program so that the results can be applied as early as possible to the needs of LLNL programs. This annual report, organized by thrust area, describes activities conducted within the Program for the fiscal year, 1991. Its intent is to provide timely summaries of objectives, theories, methods, and results

  14. Construction of Engineering Education Program based on the Alumni's Evaluation of the Educational Outcome

    Science.gov (United States)

    Tsukamoto, Takehiko; Nishizawa, Hitoshi

    The Department of Electrical and Electronic Engineering in Toyota National College of Technology has put great emphasis on fundamental subjects, such as “electrical and electronic circuit" and “electromagnetism" more than 40 years. On the other hand, several issues of our college were clarified by the alumni's evaluation of the educational outcome in 2002. The most serious issue was low achievement of English and Social education. The alumni of all generation are dissatisfied with their low skill in English communication. As a part of the educational reforms, our department has constructed a new engineering education program focusing on fundamental ability. We introduced many problem-based-learning experiments and the compulsory subjects such as “English communication for electrical engineers" and “Engineering Ethics" into this program. Great educative results are obtained by these improvements. As a typical example, the scores of all 2nd grade students of advanced engineering course in TOEIC tests became 450 points or more. Our program has been authorized by JABEE since 2004.

  15. Crosstalk between Substrates and Rho-Associated Kinase Inhibitors in Cryopreservation of Tissue-Engineered Constructs

    Directory of Open Access Journals (Sweden)

    Arindam Bit

    2017-01-01

    Full Text Available It is documented that human mesenchymal stem cells (hMSCs can be differentiated into various types of cells to present a tool for tissue engineering and regenerative medicine. Thus, the preservation of stem cells is a crucial factor for their effective long-term storage that further facilitates their continuous supply and transportation for application in regenerative medicine. Cryopreservation is the most important, practicable, and the only established mechanism for long-term preservation of cells, tissues, and organs, and engineered tissues; thus, it is the key step for the improvement of tissue engineering. A significant portion of MSCs loses cellular viability while freeze-thawing, which represents an important technical limitation to achieving sufficient viable cell numbers for maximum efficacy. Several natural and synthetic materials are extensively used as substrates for tissue engineering constructs and cryopreservation because they promote cell attachment and proliferation. Rho-associated kinase (ROCK inhibitors can improve the physiological function and postthaw viability of cryopreserved MSCs. This review proposes a crosstalk between substrate topology and interaction of cells with ROCK inhibitors. It is shown that incorporation of ionic nanoparticles in the presence of an external electrical field improves the generation of ROCK inhibitors to safeguard cellular viability for the enhanced cryopreservation of engineered tissues.

  16. Annual report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1996

    International Nuclear Information System (INIS)

    1997-08-01

    This report summarizes research and educational activities, operation status of the research facilities of the Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo on fiscal year 1996. This facility has four major research facilities such as fast neutron source reactor 'Yayoi', electron Linac, fundamental experiment facility for nuclear fusion reactor blanket design and high fluence irradiation facility(HIT). Education and research activities are conducted in a wide fields of nuclear engineering using these facilities. The former two facilities are available for various studies by universities all over Japan, facility for nuclear fusion reactor blanket design is utilized for research within the Faculty of Engineering and HIT is used for the research within the University of Tokyo. The facility established a plan to reorganized into a nation wide research collaboration center in fiscal year 1995 and after further discussion of a future program it is decided to hold 'Nuclear energy symposium' periodically after fiscal year 1997 as a part of the activity for appealing the research results to the public. (G.K.)

  17. The interplay between tissue growth and scaffold degradation in engineered tissue constructs

    KAUST Repository

    O’Dea, R. D.

    2012-09-18

    In vitro tissue engineering is emerging as a potential tool to meet the high demand for replacement tissue, caused by the increased incidence of tissue degeneration and damage. A key challenge in this field is ensuring that the mechanical properties of the engineered tissue are appropriate for the in vivo environment. Achieving this goal will require detailed understanding of the interplay between cell proliferation, extracellular matrix (ECM) deposition and scaffold degradation. In this paper, we use a mathematical model (based upon a multiphase continuum framework) to investigate the interplay between tissue growth and scaffold degradation during tissue construct evolution in vitro. Our model accommodates a cell population and culture medium, modelled as viscous fluids, together with a porous scaffold and ECM deposited by the cells, represented as rigid porous materials. We focus on tissue growth within a perfusion bioreactor system, and investigate how the predicted tissue composition is altered under the influence of (1) differential interactions between cells and the supporting scaffold and their associated ECM, (2) scaffold degradation, and (3) mechanotransduction-regulated cell proliferation and ECM deposition. Numerical simulation of the model equations reveals that scaffold heterogeneity typical of that obtained from μCT scans of tissue engineering scaffolds can lead to significant variation in the flow-induced mechanical stimuli experienced by cells seeded in the scaffold. This leads to strong heterogeneity in the deposition of ECM. Furthermore, preferential adherence of cells to the ECM in favour of the artificial scaffold appears to have no significant influence on the eventual construct composition; adherence of cells to these supporting structures does, however, lead to cell and ECM distributions which mimic and exaggerate the heterogeneity of the underlying scaffold. Such phenomena have important ramifications for the mechanical integrity of

  18. Pattern of Bone Generation after Irradiation in Vascularized Tissue Engineered Constructs.

    Science.gov (United States)

    Eweida, Ahmad; Fathi, Ibrahim; Eltawila, Ahmed M; Elsherif, Ahmad M; Elkerm, Yasser; Harhaus, Leila; Kneser, Ulrich; Sakr, Mahmoud F

    2018-02-01

     Regenerative medicine modalities provide promising alternatives to conventional reconstruction techniques but are still deficient after malignant tumor excision or irradiation due to defective vascularization.  We investigated the pattern of bone formation in axially vascularized tissue engineering constructs (AVTECs) after irradiation in a study that mimics the clinical scenario after head and neck cancer. Heterotopic bone generation was induced in a subcutaneously implanted AVTEC in the thigh of six male New Zealand rabbits. The tissue construct was made up of Nanobone (Artoss GmbH; Rostock, Germany) granules mixed with autogenous bone marrow and 80 μL of bone morphogenic protein-2 at a concentration of 1.5 μg/μL. An arteriovenous loop was created microsurgically between the saphenous vessels and implanted in the core of the construct to induce axial vascularization. The constructs were subjected to external beam irradiation on postoperative day 20 with a single dose of 15 Gy. The constructs were removed 20 days after irradiation and subjected to histological and immunohistochemical analysis for vascularization, bone formation, apoptosis, and cellular proliferation.  The vascularized constructs showed homogenous vascularization and bone formation both in their central and peripheral regions. Although vascularity, proliferation, and apoptosis were similar between central and peripheral regions of the constructs, significantly more bone was formed in the central regions of the constructs.  The study shows for the first time the pattern of bone formation in AVTECs after irradiation using doses comparable to those applied after head and neck cancer. Axial vascularization probably enhances the osteoinductive properties in the central regions of AVTECs after irradiation. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  19. Engineering behavior of small-scale foundation piers constructed from alternative materials

    Science.gov (United States)

    Prokudin, Maxim Mikhaylovich

    Testing small-scale prototype pier foundations to evaluate engineering behavior is an alternative to full-scale testing that facilitates testing of several piers and pier groups at relatively low cost. In this study, various pier systems and pier groups at one tenth scale were subjected to static vertical loading under controlled conditions to evaluate stiffness, bearing capacity, and group efficiency. Pier length, material properties and methods of installation were evaluated. Pier length to diameter ratios varied between four and eight. A unique soil pit with dimensions of 2.1 m in width, 1.5 m in length and 2.0 m in depth was designed to carry out this research. The test pit was filled with moisture conditioned and compacted Western Iowa loess. A special load test frame was designed and fabricated to provide up to 25,000 kg vertical reaction force for load testing. A load cell and displacement instrumentation was setup to capture the load test data. Alternative materials to conventional cement concrete were studied. The pier materials evaluated in this study included compacted aggregate, cement stabilized silt, cementitious grouts, and fiber reinforced silt. Key findings from this study demonstrated that (1) the construction method influences the behavior of aggregate piers, (2) the composition of the pier has a significant impact on the stiffness, (3) group efficiencies were found to be a function of pier length and pier material, (4) in comparison to full-scale testing the scaled piers were found to produce a stiffer response with load-settlement and bearing capacities to be similar. Further, although full-scale test results were not available for all pier materials, the small-scale testing provided a means for comparing results between pier systems. Finally, duplicate pier tests for a given length and material were found to be repeatable.

  20. Discourse on Narrative Research: The Construction Zone--Literary Elements in Narrative Research

    Science.gov (United States)

    Coulter, Cathy A.; Smith, Mary Lee

    2009-01-01

    Narrative research has become part of the landscape of education inquiry, yet its theory and practice are still debated and evolving. This article addresses the construction of narratives using literary elements common to nonfiction and fiction writings. The authors discuss these elements and use four narratives to illustrate them. They address…

  1. General aviation internal combustion engine research programs at NASA-Lewis Research Center

    Science.gov (United States)

    Willis, E. A.

    1978-01-01

    An update is presented of non-turbine general aviation engine programs underway at the NASA-Lewis Research Center in Cleveland, Ohio. The program encompasses conventional, lightweight diesel and rotary engines. Its three major thrusts are: (a) reduced SFC's; (b) improved fuels tolerance; and (c) reducing emissions. Current and planned future programs in such areas as lean operation, improved fuel management, advanced cooling techniques and advanced engine concepts, are described. These are expected to lay the technology base, by the mid to late 1980's, for engines whose life cycle fuel costs are 30 to 50% lower than today's conventional engines.

  2. Global network on engineering education research and expertise in PBL

    DEFF Research Database (Denmark)

    Enemark, Stig; Kolmos, Anette; Moesby, Egon

    2006-01-01

    in order to facilitate better access to and co-operation within the PBL area. One of the absolute important tasks for UCPBL is to provide evidence for the effectiveness of PBL worldwide. Thus, there is a special attempt to establish links between engineering education researchers in this field....... This involves considerations concerning what is engineering education research – and how do we promote research based staff and educational development.......The UCPBL Centre for Problem Based Learning is based at Aalborg University, Denmark, known world-wide for its successful educational approach based on problem oriented project work. Due to more than 30 years of experience in utilizing PBL-learning principles in Engineering Education, an increasing...

  3. Engineering Design Thinking and Information Gathering. Final Report. Research in Engineering and Technology Education

    Science.gov (United States)

    Mentzer, Nathan

    2011-01-01

    The objective of this research was to explore the relationship between information access and design solution quality of high school students presented with an engineering design problem. This objective is encompassed in the research question driving this inquiry: How does information access impact the design process? This question has emerged in…

  4. Systems Engineering Research Needs and Workforce Development Assessment

    Science.gov (United States)

    2018-01-31

    research cluster had no single research center as the most interested in it, but had a high uniformity in the distribution of research centers...all our engagements. • Lack of trust among major organizations, particularly between acquisition and contractors , inhibits capability. • Concern...from a policy culture to an incentive culture Mission Engineering Management, Culture and Agility IC DoD - 2 tension building the optimized

  5. Monitoring Bone Tissue Engineered (BTE) Constructs Based on the Shifting Metabolism of Differentiating Stem Cells.

    Science.gov (United States)

    Simmons, Aaron D; Sikavitsas, Vassilios I

    2018-01-01

    Ever-increasing demand for bone grafts necessitates the realization of clinical implementation of bone tissue engineered constructs. The predominant hurdle to implementation remains to be securing FDA approval, based on the lack of viable methods for the rigorous monitoring of said constructs. The study presented herein details a method for such monitoring based on the shifting metabolism of mesenchymal stem cells (MSCs) as they differentiate into osteoblasts. To that end, rat MSCs seeded on 85% porous spunbonded poly(L-lactic acid) scaffolds were cultured in flow perfusion bioreactors with baseline or osteoinductive media, and levels of key physio-metabolic markers (oxygen, glucose, osteoprotegerin, and osteocalcin) were monitored throughout culture. Comparison of these non-destructively obtained values and current standard destructive analyses demonstrated key trends useful for the concurrent real-time monitoring of construct cellularity and maturation. Principle among these is the elucidation of the ratio of the rates of oxygen uptake to glucose consumption as a powerful quality marker. This ratio, supported on a physiological basis, has been shown herein to be reliable in the determination of both construct maturation (defined as osteoblastic differentiation and accompanying mineralization) and construct cellularity. Supplementary monitoring of OPG and OCN are shown to provide further validation of such metrics.

  6. Armstrong Flight Research Center Research Technology and Engineering 2017

    Science.gov (United States)

    Voracek, David F. (Editor)

    2018-01-01

    I am delighted to present this report of accomplishments at NASA's Armstrong Flight Research Center. Our dedicated innovators possess a wealth of performance, safety, and technical capabilities spanning a wide variety of research areas involving aircraft, electronic sensors, instrumentation, environmental and earth science, celestial observations, and much more. They not only perform tasks necessary to safely and successfully accomplish Armstrong's flight research and test missions but also support NASA missions across the entire Agency. Armstrong's project teams have successfully accomplished many of the nation's most complex flight research projects by crafting creative solutions that advance emerging technologies from concept development and experimental formulation to final testing. We are developing and refining technologies for ultra-efficient aircraft, electric propulsion vehicles, a low boom flight demonstrator, air launch systems, and experimental x-planes, to name a few. Additionally, with our unique location and airborne research laboratories, we are testing and validating new research concepts. Summaries of each project highlighting key results and benefits of the effort are provided in the following pages. Technology areas for the projects include electric propulsion, vehicle efficiency, supersonics, space and hypersonics, autonomous systems, flight and ground experimental test technologies, and much more. Additional technical information is available in the appendix, as well as contact information for the Principal Investigator of each project. I am proud of the work we do here at Armstrong and am pleased to share these details with you. We welcome opportunities for partnership and collaboration, so please contact us to learn more about these cutting-edge innovations and how they might align with your needs.

  7. Plasmid DNA transfection using magnetite cationic liposomes for construction of multilayered gene-engineered cell sheet.

    Science.gov (United States)

    Ino, Kosuke; Kawasumi, Tamayo; Ito, Akira; Honda, Hiroyuki

    2008-05-01

    Modification of cellular functions by overexpression of genes is being increasingly practiced for tissue engineering. In the present study, we investigated whether transfection efficiency could be enhanced by magnetofection that involves the use of plasmid DNA (pDNA)/magnetite cationic liposomes (MCLs) complexes (pDNA/MCL) and magnetic force. The transfection efficiencies of the magnetofection technique by pDNA/MCL in fibroblasts and keratinocytes using reporter genes were 36- and 10-fold higher, respectively, than those of a lipofection technique by cationic liposomes. Moreover, in vitro construction of three-dimensional (3D) tissues is an important challenge. We recently proposed a novel technique termed "magnetic force-based tissue engineering" (Mag-TE) to produce 3D tissues. Since the fibroblasts after magnetofection incorporated both magnetite nanoparticles and pDNA, we investigated whether multilayered heterotypic cell sheets expressing transgene could be fabricated by Mag-TE. First, the fibroblasts were seeded onto an ultra-low attachment culture plate. When a magnet was placed under the plate, the cells accumulated at the bottom of the culture plate. After 24 h of culture, the transgene-expressing cells formed a multilayered cell sheet-like structure. These results indicated that MCLs are a potent biomanipulation tool for both gene transfer and 3D tissue construction, suggesting that these techniques are useful for tissue engineering. Copyright 2007 Wiley Periodicals, Inc.

  8. Hybrid cellular automaton modeling of nutrient modulated cell growth in tissue engineering constructs.

    Science.gov (United States)

    Chung, C A; Lin, Tze-Hung; Chen, Shih-Di; Huang, Hsing-I

    2010-01-21

    Mathematic models help interpret experimental results and accelerate tissue engineering developments. We develop in this paper a hybrid cellular automata model that combines the differential nutrient transport equation to investigate the nutrient limited cell construct development for cartilage tissue engineering. Individual cell behaviors of migration, contact inhibition and cell collision, coupled with the cell proliferation regulated by oxygen concentration were carefully studied. Simplified two-dimensional simulations were performed. Using this model, we investigated the influence of cell migration speed on the overall cell growth within in vitro cell scaffolds. It was found that intense cell motility can enhance initial cell growth rates. However, since cell growth is also significantly modulated by the nutrient contents, intense cell motility with conventional uniform cell seeding method may lead to declined cell growth in the final time because concentrated cell population has been growing around the scaffold periphery to block the nutrient transport from outside culture media. Therefore, homogeneous cell seeding may not be a good way of gaining large and uniform cell densities for the final results. We then compared cell growth in scaffolds with various seeding modes, and proposed a seeding mode with cells initially residing in the middle area of the scaffold that may efficiently reduce the nutrient blockage and result in a better cell amount and uniform cell distribution for tissue engineering construct developments.

  9. Engineering zonal cartilage through bioprinting collagen type II hydrogel constructs with biomimetic chondrocyte density gradient.

    Science.gov (United States)

    Ren, Xiang; Wang, Fuyou; Chen, Cheng; Gong, Xiaoyuan; Yin, Li; Yang, Liu

    2016-07-20

    Cartilage tissue engineering is a promising approach for repairing and regenerating cartilage tissue. To date, attempts have been made to construct zonal cartilage that mimics the cartilaginous matrix in different zones. However, little attention has been paid to the chondrocyte density gradient within the articular cartilage. We hypothesized that the chondrocyte density gradient plays an important role in forming the zonal distribution of extracellular matrix (ECM). In this study, collagen type II hydrogel/chondrocyte constructs were fabricated using a bioprinter. Three groups were created according to the total cell seeding density in collagen type II pre-gel: Group A, 2 × 10(7) cells/mL; Group B, 1 × 10(7) cells/mL; and Group C, 0.5 × 10(7) cells/mL. Each group included two types of construct: one with a biomimetic chondrocyte density gradient and the other with a single cell density. The constructs were cultured in vitro and harvested at 0, 1, 2, and 3 weeks for cell viability testing, reverse-transcription quantitative PCR (RT-qPCR), biochemical assays, and histological analysis. We found that total ECM production was positively correlated with the total cell density in the early culture stage, that the cell density gradient distribution resulted in a gradient distribution of ECM, and that the chondrocytes' biosynthetic ability was affected by both the total cell density and the cell distribution pattern. Our results suggested that zonal engineered cartilage could be fabricated by bioprinting collagen type II hydrogel constructs with a biomimetic cell density gradient. Both the total cell density and the cell distribution pattern should be optimized to achieve synergistic biological effects.

  10. Final Report on the Audit of Architect-Engineer Contracting at the Officer in Charge of Construction, Naval Facilities Engineering Command Contracts, Mediterranean, Madrid, Spain

    Science.gov (United States)

    1990-11-30

    This is our final report on the audit of Architect-Engineer Contracting for the Officer in Charge of Construction, Naval Facilities Engineering...Command Contracts, Mediterranean, for your information and use. This is the fourth in a series of reports issued as part of the audit of architect-engineer...A-E) contracting. The Contract Management Directorate made the audit from August 1989 through July 1990. When we expanded the audit scope to include

  11. [Construction of a capsular tissue-engineered ureteral stent seeded with autologous urothelial cells].

    Science.gov (United States)

    Tan, Haisong; Fu, Weijun; Li, Jianqiang; Wang, Zhongxin; Li, Gang; Ma, Xin; Dong, Jun; Gao, Jiangping; Wang, Xiaoxiong; Zhang, Xu

    2013-01-01

    To investigate the feasibility of constructing a capsular poly L-lactic acid (PLLA) ureteral stent seeded with autologous urothelial cells using tissue engineering methods. The capsular ureteral stent was constructed by subcutaneously embedding PLLA ureteral stent in the back of beagles for 3 weeks to induce the formation of connective tissue on the surfaces. After decellularization of the stent, the expanded autologous urothelial cells were seeded on the stent. The surface structure and cell adhesion of the stent were observed using HE staining, scanning electron microscope (SEM) and immunocytochemical staining. MTT assay was used to evaluate urothelial cell proliferation on the capsular PLLA ureteral stent and on circumferential small intestinal submucosa graft. HE staining and VIII factor immunohistochemistry revealed numerous capillaries in the connective tissue encapsulating the stent without obvious local inflammatory response. The results of SEM and immunocytochemical staining showed that the capsule contained rich collagenic fibers forming three-dimensional structures, and the seeded autologous urothelial cells could adhere and well aligned on the surface. MTT assay showed normal growth of the cells on the stent as compared with the cells grown on circumferential small intestinal submucosa graft. The capsular PLLA ureteral stent allows adhesion and proliferation of autologous urothelial cells and shows a potential in applications of constructing tissue-engineered ureter.

  12. 34 CFR 350.34 - Which Rehabilitation Engineering Research Centers must have an advisory committee?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Which Rehabilitation Engineering Research Centers must... Engineering Research Centers Does the Secretary Assist? § 350.34 Which Rehabilitation Engineering Research Centers must have an advisory committee? A Rehabilitation Engineering Research Center conducting research...

  13. International cooperation for promotion of nuclear science and engineering research

    International Nuclear Information System (INIS)

    Shibata, Toshikazu; Sugiyama, Kazusuke; Nakazawa, Masaharu; Katoh, Toshio; Kimura, Itsuro.

    1993-01-01

    For promotion of nuclear science and engineering research, examinations were made on the possibilities and necessary measures to extend joint research at international level. The present article is a summary of the reports of investigations performed during FY 1986 through 1991 by the Special Committee of the AESJ for Feasibility Study on International Cooperation for Promotion of Nuclear Science and Engineering Research, under contract with Science and Technology Agency of Japan. Background information was collected on the present status of scientific research facilities in US, European and Asian countries on one hand, and on the expectations and prospects of Japanese scientists on the other hand. Based on the analysis of these data, some measures necessary to expand the international cooperation were proposed. It was emphasized that international joint research on a reciprocal basis would be effective in order to strengthen the technological basis of peaceful uses of nuclear energy. Problems to be solved for the new development were also discussed. (author)

  14. Not so global: a bibliometric look at engineering education research

    Science.gov (United States)

    Williams, Bill; Wankat, Phillip C.; Neto, Pedro

    2018-03-01

    It has been suggested that Engineering Education Research (EER) is going global. If this were the case we would assume that the research of EER scholars in different parts of the globe would be informed by literature describing prior work within and beyond their home country/region. The authors set out to test this hypothesis by applying citation analysis to research presented in four publication venues: the annual conferences organised by ASEE (American Society of Engineering Education) and SEFI (European Society of Engineering Education) and two archival journals published by these two societies: Journal of Engineering Education (JEE) and European Journal of Engineering Education (EJEE). Our findings from the analysis of 4321 publications show that citations in ASEE conferences are dominated by sources with US affiliations, whereas the SEFI data show that while US sources are frequently cited, European and other authors are also well represented. With regard to the journals JEE and EJEE, a similar pattern is observed. These results suggest that, in citation terms, European EER is relatively global but US EER is not. The authors conclude by suggesting that if the EER community is to aspire to quality scholarship, there needs to be debate around how such issues can be tackled.

  15. E-COCOMO: The Extended COst Constructive MOdel for Cleanroom Software Engineering

    Directory of Open Access Journals (Sweden)

    Hitesh KUMAR SHARMA

    2014-02-01

    Full Text Available Mistakes create rework. Rework takes time and increases costs. The traditional software engineering methodology defines the ratio of Design:Code:Test as 40:20:40. As we can easily see that 40% time and efforts are used in testing phase in traditional approach, that means we have to perform rework again if we found some bugs in testing phase. This rework is being performed after Design and code phase. This rework will increase the cost exponentially. The cleanroom software engineering methodology controls the exponential growth in cost by removing this rework. It says that "do the work correct in first attempt and move to next phase after getting the proof of correctness". This new approach minimized the rework and reduces the cost in the exponential ratio. Due to the removal of testing phase, the COCOMO (COst COnstructive MOdel used for the traditional engineering is not directly applicable in cleanroom software engineering. The traditional cost drivers used for traditional COCOMO needs to be revised. We have proposed the Extended version of COCOMO (i.e. E-COCOMO in which we have incorporated some new cost drivers. This paper explains the proposed E-COCOMO and the detailed description of proposed new cost driver.

  16. Establishing Early Functional Perfusion and Structure in Tissue Engineered Cardiac Constructs.

    Science.gov (United States)

    Wang, Bo; Patnaik, Sourav S; Brazile, Bryn; Butler, J Ryan; Claude, Andrew; Zhang, Ge; Guan, Jianjun; Hong, Yi; Liao, Jun

    2015-01-01

    Myocardial infarction (MI) causes massive heart muscle death and remains a leading cause of death in the world. Cardiac tissue engineering aims to replace the infarcted tissues with functional engineered heart muscles or revitalize the infarcted heart by delivering cells, bioactive factors, and/or biomaterials. One major challenge of cardiac tissue engineering and regeneration is the establishment of functional perfusion and structure to achieve timely angiogenesis and effective vascularization, which are essential to the survival of thick implants and the integration of repaired tissue with host heart. In this paper, we review four major approaches to promoting angiogenesis and vascularization in cardiac tissue engineering and regeneration: delivery of pro-angiogenic factors/molecules, direct cell implantation/cell sheet grafting, fabrication of prevascularized cardiac constructs, and the use of bioreactors to promote angiogenesis and vascularization. We further provide a detailed review and discussion on the early perfusion design in nature-derived biomaterials, synthetic biodegradable polymers, tissue-derived acellular scaffolds/whole hearts, and hydrogel derived from extracellular matrix. A better understanding of the current approaches and their advantages, limitations, and hurdles could be useful for developing better materials for future clinical applications.

  17. Construction of tissue-engineered small-diameter vascular grafts in fibrin scaffolds in 30 days.

    Science.gov (United States)

    Gui, Liqiong; Boyle, Michael J; Kamin, Yishai M; Huang, Angela H; Starcher, Barry C; Miller, Cheryl A; Vishnevetsky, Michael J; Niklason, Laura E

    2014-05-01

    Tissue-engineered small-diameter vascular grafts have been developed as a promising alternative to native veins or arteries for replacement therapy. However, there is still a crucial need to improve the current approaches to render the tissue-engineered blood vessels more favorable for clinical applications. A completely biological blood vessel (3-mm inner diameter) was constructed by culturing a 50:50 mixture of bovine smooth muscle cells (SMCs) with neonatal human dermal fibroblasts in fibrin gels. After 30 days of culture under pulsatile stretching, the engineered blood vessels demonstrated an average burst pressure of 913.3±150.1 mmHg (n=6), a suture retention (53.3±15.4 g) that is suitable for implantation, and a compliance (3.1%±2.5% per 100 mmHg) that is comparable to native vessels. These engineered grafts contained circumferentially aligned collagen fibers, microfibrils and elastic fibers, and differentiated SMCs, mimicking a native artery. These promising mechanical and biochemical properties were achieved in a very short culture time of 30 days, suggesting the potential of co-culturing SMCs with fibroblasts in fibrin gels to generate functional small-diameter vascular grafts for vascular reconstruction surgery.

  18. Design and Construction of Operation Bridge for Research Reactor

    International Nuclear Information System (INIS)

    Jung, Kwangsub; Choi, Jinbok; Lee, Jongmin; Oh, Jinho

    2015-01-01

    The operation bridge contains a lower working deck mounted on a saddle that travels on rails. Upright members are mounted on the saddle to support the upper structure and two hoist monorails. The saddle contains an anti-derail system that is composed of seismic lugs and guide rollers. The operation bridge travels along the rails to transport the fuel assembly, irradiated object, and reactor components in the pools by using tools. Hoists are installed at the top girder. The hoist is suspended from the monorail by means of a motor driven trolley that runs along the monorail. Movements of hoist and trolley are controlled by using the control pendant switch. Processes of design and construction of the operation bridge for the research reactor are introduced. The operation bridge is designed under consideration of functions of handling equipment in the pool and operational limits for safety. Structural analysis is carried out to evaluate the structural integrity in the seismic events. Tests and inspections are also performed during fabrication and installation to confirm the function and safety of the operation bridge

  19. Concept document of the repository-based software engineering program: A constructive appraisal

    Science.gov (United States)

    1992-01-01

    A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

  20. Magnetic resonance microscopy for monitoring osteogenesis in tissue-engineered construct in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Xu Huihui [Bioengineering Department (MC 063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607-7052 (United States); Othman, Shadi F [Bioengineering Department (MC 063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607-7052 (United States); Hong Liu [Bioengineering Department (MC 063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607-7052 (United States); Peptan, Ioana A [Bioengineering Department (MC 063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607-7052 (United States); Magin, Richard L [Bioengineering Department (MC 063), University of Illinois at Chicago, 851 South Morgan Street, Chicago, IL 60607-7052 (United States)

    2006-02-07

    Magnetic resonance microscopy (MRM) is used to monitor osteogenesis in tissue-engineered constructs. Measurements of the developing tissue's MR relaxation times (T{sub 1} and T{sub 2}), apparent diffusion coefficient (ADC) and elastic shear modulus were conducted over a 4-week growth period using an 11.74 T Bruker spectrometer with an imaging probe adapted for MR elastography (MRE). Both the relaxation times and the ADC show a statistically significant decrease after only one week of tissue development while the tissue stiffness increases progressively during the first two weeks of in vitro growth. The measured MR parameters are correlated with histologically monitored osteogenic tissue development. This study shows that MRM can provide quantitative data with which to characterize the growth and development of tissue-engineered bone.

  1. Synthetic constructs in/for the environment: managing the interplay between natural and engineered Biology.

    Science.gov (United States)

    Schmidt, Markus; de Lorenzo, Víctor

    2012-07-16

    The plausible release of deeply engineered or even entirely synthetic/artificial microorganisms raises the issue of their intentional (e.g. bioremediation) or accidental interaction with the Environment. Containment systems designed in the 1980s-1990s for limiting the spread of genetically engineered bacteria and their recombinant traits are still applicable to contemporary Synthetic Biology constructs. Yet, the ease of DNA synthesis and the uncertainty on how non-natural properties and strains could interplay with the existing biological word poses yet again the challenge of designing safe and efficacious firewalls to curtail possible interactions. Such barriers may include xeno-nucleic acids (XNAs) instead of DNA as information-bearing molecules, rewriting the genetic code to make it non-understandable by the existing gene expression machineries, and/or making growth dependent on xenobiotic chemicals. Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  2. CD34/CD133 enriched bone marrow progenitor cells promote neovascularization of tissue engineered constructs in vivo

    Directory of Open Access Journals (Sweden)

    Marietta Herrmann

    2014-11-01

    We demonstrate that this population of cells, isolated in a clinically relevant manner and cultured with autologous growth factors readily promoted neovascularization in tissue engineered constructs in vivo enabling a potential translation into the clinic.

  3. Research on Construction Optimization of Three-Connected-Arch Hydraulic Underground Cavities Considering Creep Property

    Directory of Open Access Journals (Sweden)

    Bao-yun Zhao

    2014-01-01

    Full Text Available In order to prevent the creep of surrounding rock in long-term construction, with consideration of different construction methods and other factors during the construction of large-scale underground cavity, three different construction schemes are designed for specific projects and a nonlinear viscoelastic-plastic creep model which can describe rock accelerated creeping is introduced and applied to construction optimization calculation of the large-scale three-connected-arch hydraulic underground cavity through secondary development of FLAC3D. The results show that the adoption of middle cavity construction method, the second construction method, enables the maximum vault displacement of 16.04 mm. This method results in less stress redistribution and plastic zone expansion to the cavity’s surrounding rock than the other two schemes, which is the safest construction scheme. The conclusion can provide essential reference and guidance to similar engineering for construction optimization.

  4. Engineering research, development and technology. Thrust area report, FY93

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    The mission of the Engineering Research, Development, and Technology Program at Lawrence Livermore National Laboratory (LLNL) is to develop the technical staff, tools, and facilities needed to support current and future LLNL programs. The efforts are guided by a dual-benefit research and development strategy that supports Department of Energy missions, such as national security through nuclear deterrence and economic competitiveness through partnerships with U.S. industry. This annual report, organized by thrust area, describes the activities for the fiscal year 1993. The report provides timely summaries of objectives, methods, and results from nine thrust areas for this fiscal year: Computational Electronics and Electromagnetics; Computational Mechanics; Diagnostics and Microelectronics; Fabrication Technology; Materials Science and Engineering; Power Conversion Technologies; Nondestructive Evaluation; Remote Sensing, Imaging, and Signal Engineering; and Emerging Technologies. Separate abstracts were prepared for 47 papers in this report.

  5. Biphasic Finite Element Modeling Reconciles Mechanical Properties of Tissue-Engineered Cartilage Constructs Across Testing Platforms.

    Science.gov (United States)

    Meloni, Gregory R; Fisher, Matthew B; Stoeckl, Brendan D; Dodge, George R; Mauck, Robert L

    2017-07-01

    Cartilage tissue engineering is emerging as a promising treatment for osteoarthritis, and the field has progressed toward utilizing large animal models for proof of concept and preclinical studies. Mechanical testing of the regenerative tissue is an essential outcome for functional evaluation. However, testing modalities and constitutive frameworks used to evaluate in vitro grown samples differ substantially from those used to evaluate in vivo derived samples. To address this, we developed finite element (FE) models (using FEBio) of unconfined compression and indentation testing, modalities commonly used for such samples. We determined the model sensitivity to tissue radius and subchondral bone modulus, as well as its ability to estimate material parameters using the built-in parameter optimization tool in FEBio. We then sequentially tested agarose gels of 4%, 6%, 8%, and 10% weight/weight using a custom indentation platform, followed by unconfined compression. Similarly, we evaluated the ability of the model to generate material parameters for living constructs by evaluating engineered cartilage. Juvenile bovine mesenchymal stem cells were seeded (2 × 10 7 cells/mL) in 1% weight/volume hyaluronic acid hydrogels and cultured in a chondrogenic medium for 3, 6, and 9 weeks. Samples were planed and tested sequentially in indentation and unconfined compression. The model successfully completed parameter optimization routines for each testing modality for both acellular and cell-based constructs. Traditional outcome measures and the FE-derived outcomes showed significant changes in material properties during the maturation of engineered cartilage tissue, capturing dynamic changes in functional tissue mechanics. These outcomes were significantly correlated with one another, establishing this FE modeling approach as a singular method for the evaluation of functional engineered and native tissue regeneration, both in vitro and in vivo.

  6. Design and construction of engineering test device of a multi-purpose radwaste incineration system

    International Nuclear Information System (INIS)

    Wang Peiyi; Zhou Lianquan; Ma Mingxie; Qiu Mingcai; Yang Liguo; Li Xiaohai; Zhang Xiaobin; Lu Xiaowu; Dong Jingling; Wang Xujin; Li Chuanlian; Yang Baomin

    2002-01-01

    The author describes designs of main un-standard devices, monitoring system and safety system, as well as construction of the engineering system devices for a multi-purpose radwaste incineration system. Un-standard devices include waste crusher, pyrolysis furnace, incinerator furnace, cool stream dilution device and bag filter, etc. The monitoring system mainly includes industrial controlled computer, supported by conventional electrical equipment and instruments. Designs of system safety takes account of containment of radioactive materials fire-prevention, explosion prevention, anti-corrosion, redundance and reservation, emergency system, controlling and electric safety system, etc. Results show that main technological system remains good airtight with leakage ratio at 0.67%

  7. Projects of Iberdrola Engineering and Construction on the Flamanville 3 EPR

    International Nuclear Information System (INIS)

    Zornoza, J.; Dumas, H.; Sesma, J. L.; Cubian, B.; Diaz, J. I.

    2013-01-01

    Iberdrola Engineering and Construction is participating during the last 5 years in 5 projects on the Flamanville 3 EPR, both in the nuclear island and conventional island and the pump house. These projects represent a challenge from the technical point of view due to the high requirements applicable to the project because of the experience feedback of the operator EDF and of compliance with new regulations that have emerged since the completion of the last nuclear power station in France. This paper presents the description of these projects, as well as its current status. (Author)

  8. Construction and evaluation of urinary bladder bioreactor for urologic tissue-engineering purposes.

    LENUS (Irish Health Repository)

    Davis, Niall F

    2012-01-31

    OBJECTIVE: To design and construct a urinary bladder bioreactor for urologic tissue-engineering purposes and to compare the viability and proliferative activity of cell-seeded extracellular matrix scaffolds cultured in the bioreactor with conventional static growth conditions. MATERIALS AND METHODS: A urinary bladder bioreactor was designed and constructed to replicate physiologic bladder dynamics. The bioreactor mimicked the filling pressures of the human bladder by way of a cyclical low-delivery pressure regulator. In addition, cell growth was evaluated by culturing human urothelial cells (UCs) on porcine extracellular matrix scaffolds in the bioreactor and in static growth conditions for 5 consecutive days. The attachment, viability, and proliferative potential were assessed and compared with quantitative viability indicators and by fluorescent markers for intracellular esterase activity and plasma membrane integrity. Scaffold integrity was characterized with scanning electron microscopy and 4\\

  9. The in vivo characteristics of genetically engineered divalent and tetravalent single-chain antibody constructs

    International Nuclear Information System (INIS)

    Wittel, Uwe A.; Jain, Maneesh; Goel, Apollina; Chauhan, Subhash C.; Colcher, David; Batra, Surinder K.

    2005-01-01

    Engineered multivalent single-chain Fv (scFv) constructs have been demonstrated to exhibit rapid blood clearance and better tumor penetration. To understand the short plasma half-life of multivalent single-chain antibody fragments, the pharmacokinetic properties of covalent dimeric scFv [sc(Fv) 2 ], noncovalent tetrameric scFv {[sc(Fv) 2 ] 2 } and IgG of MAb CC49 were examined. The scFvs displayed an ability to form higher molecular aggregates in vivo. A specific proteolytic cleavage of the linker sequence of the covalent dimeric or a deterioration of the noncovalent association of the dimeric scFv into tetravalent scFv constructs was not observed. In conclusion, sc(Fv) 2 and [sc(Fv) 2 ] 2 are stable in vivo and have significant potential for diagnostic and therapeutic applications

  10. A Continuing Education Short Course and Engineering Curriculum to Accelerate Workforce Development in Wind Power Plant Design, Construction, and Operations

    Energy Technology Data Exchange (ETDEWEB)

    Tinjum, James [Univ. of Wisconsin, Madison, WI (United States)

    2012-11-29

    Significant advances in wind turbine technology and wind turbine power plant capabilities are appearing in the U.S. Sites that only 10 years ago might have been overlooked are being considered for build out. However, the development of a skilled workforce in the engineering fields and construction trades lags the potential market, especially if the industry is expected to site, design, construct, and operate sufficient wind power plant sites to meet the potential for 20% wind energy by 2030. A select few firms have penetrated the engineer-procure-construction (EPC) market of wind power plant construction. Competition and know-how in this market is vital to achieve cost-effective, design-construct solutions. The industry must produce or retrain engineers, contractors, and technicians to meet ambitious goals. Currently, few universities offer undergraduate or graduate classes that teach the basics in designing, building, and maintaining wind power plants that are safe, efficient, and productive.

  11. A new construction technique for tissue-engineered heart valves using the self-assembly method.

    Science.gov (United States)

    Tremblay, Catherine; Ruel, Jean; Bourget, Jean-Michel; Laterreur, Véronique; Vallières, Karine; Tondreau, Maxime Y; Lacroix, Dan; Germain, Lucie; Auger, François A

    2014-11-01

    Tissue engineering appears as a promising option to create new heart valve substitutes able to overcome the serious drawbacks encountered with mechanical substitutes or tissue valves. The objective of this article is to present the construction method of a new entirely biological stentless aortic valve using the self-assembly method and also a first assessment of its behavior in a bioreactor when exposed to a pulsatile flow. A thick tissue was created by stacking several fibroblast sheets produced with the self-assembly technique. Different sets of custom-made templates were designed to confer to the thick tissue a three-dimensional (3D) shape similar to that of a native aortic valve. The construction of the valve was divided in two sequential steps. The first step was the installation of the thick tissue in a flat preshaping template followed by a 4-week maturation period. The second step was the actual cylindrical 3D forming of the valve. The microscopic tissue structure was assessed using histological cross sections stained with Masson's Trichrome and Picrosirius Red. The thick tissue remained uniformly populated with cells throughout the construction steps and the dense extracellular matrix presented corrugated fibers of collagen. This first prototype of tissue-engineered heart valve was installed in a bioreactor to assess its capacity to sustain a light pulsatile flow at a frequency of 0.5 Hz. Under the light pulsed flow, it was observed that the leaflets opened and closed according to the flow variations. This study demonstrates that the self-assembly method is a viable option for the construction of complex 3D shapes, such as heart valves, with an entirely biological material.

  12. Electronic battlespace facility for research, develoment and engineering

    NARCIS (Netherlands)

    Jense, Hans; Kuijpers, N.H.L.; Elias, R.J.D.

    1997-01-01

    In order to support its research, development and engineering activities in the area of distributed simulation for training and command & control, TNO Physics and Electronics Laboratory has developed (and continues to enhance) an Electronic Battlespace Facility (EBF). This paper presents an overview

  13. Directions in engineering research: an assessment of opportunities and needs

    National Research Council Canada - National Science Library

    National Research Council Staff; Commission on Engineering and Technical Systems; Division on Engineering and Physical Sciences; National Research Council

    1987-01-01

    ... Commission on Engineering and Technical Systems National Research Council Washington, D.C. NATIONAL ACADEMY PRESS Washington, D.C. 1987 i Copyrightthe cannot be not from book, paper however, version for formatting, original authoritative the typesetting-specific the as from created publication files XML from other this and of recomposed styles, v...

  14. Call for expressions of interest: Strengthening engineering research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    cgu

    2017-08-14

    Aug 14, 2017 ... significant are the many structural barriers that pertain to the overall ... professional engineering organizations in supporting the ... and research-based solutions in the Global South, IDRC is uniquely .... to engage in the project throughout its duration through: student internships, equipment-sharing,.

  15. 77 FR 3240 - Board on Coastal Engineering Research

    Science.gov (United States)

    2012-01-23

    ... broad policy guidance and review of plans and fund requirements for the conduct of research and... objectives of the Chief of Engineers. Proposed Agenda: On Tuesday, February 7, the Executive Session is... Board, discussion of the Board functions and responsibilities, and ways to enhance the value of the...

  16. Systems Engineering Applications for Small Business Innovative Research (SBIR) Projects

    Science.gov (United States)

    2012-09-01

    Engineering processes within the SBIR community. Information was collected from multiple organizations throughout the SBIR community to support this research...Force by Program Executive Officers, Technolgy Directorates, Air Logistics Centers and Test Centers. SBIR projects are developed in three phases...found to be associated with SBIR projects and varied among organizations. Thus it became essential to conduct interviews to gather the information

  17. Plant cell engineering: current research, application and future prospects

    International Nuclear Information System (INIS)

    Wang Xunqing; Liu Luxiang

    2008-01-01

    This paper reviewed the current status of basic research in plant cell engineering, highlighted the application of embryo culture, double haploid (DH) technology, protoplast culture and somatic hybridization, somaclonal variation, rapid propagation, and bio-products production of plant-origin, and t he prospects. (authors)

  18. ChE Undergraduate Research Projects in Biomedical Engineering.

    Science.gov (United States)

    Stroeve, Pieter

    1981-01-01

    Describes an undergraduate research program in biomedical engineering at the State University of New York at Buffalo. Includes goals and faculty comments on the program. Indicates that 58 percent of projects conducted between 1976 and 1980 have been presented at meetings or published. (SK)

  19. Molecular research and genetic engineering of resistance to ...

    African Journals Online (AJOL)

    This paper reviews the recent research progress on genetic methods of resistance, the status and existing problems, traditional breeding, the main resistance mechanism, molecular markers and genetic engineering of resistance genes. It is hoped that new breeding methods and new varieties resistant to Verticillium wilt will ...

  20. Strengthening engineering research and training in Africa | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    to develop mutually beneficial research and training activities. ... to inform how national or regional engineering systems operate in sub-Saharan Africa, ... developing networks and partnerships that have the potential for scaling-up activities ... from the collaborating institution in the case of Stream 1), in English or in French.

  1. Analysis on Key Points of Construction and Management of Municipal Landscape Engineering

    Science.gov (United States)

    Liang, Mingxia; Fei, Cheng

    2018-02-01

    At present, China has made great efforts to promote the construction of ecological civilization and promote the development of ecological protection and environmental construction. It has important practical significance to maintain the ecological balance and environmental quality of our country. Especially with the gradual improvement in people’s awareness of environmental protection, so that the green of the city also put forward higher requirements at the same time with the rising of the level of urbanization. In the process of urban landscape construction, the rational planning of urban landscaping involves a lot of subject knowledge. In the green process, we should fully consider the system of urban development and construction in China, based on the design of urban development and long-term planning of the landscaping project. In addition, we must also consider the traditional layout of the city area and the physical and geographical situation and so on, to enhance the objective and scientific nature of urban landscape. Therefore, it is of great practical significance to ensure the quality of landscaping in the effective management of municipal landscape engineering.

  2. Development of a construct-based risk assessment framework for genetic engineered crops.

    Science.gov (United States)

    Beker, M P; Boari, P; Burachik, M; Cuadrado, V; Junco, M; Lede, S; Lema, M A; Lewi, D; Maggi, A; Meoniz, I; Noé, G; Roca, C; Robredo, C; Rubinstein, C; Vicien, C; Whelan, A

    2016-10-01

    Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit the scientific criteria underlying the RA process. Along these lines, the need to engage in a scientific discussion for the case of GE crops transformed with similar constructs was recently identified in Argentina. In response to this need, the Argentine branch of the International Life Sciences Institute (ILSI Argentina) convened a tripartite working group to discuss a science-based evaluation approach for transformation events developed with genetic constructs which are identical or similar to those used in previously evaluated or approved GE crops. This discussion considered new transformation events within the same or different species and covered both environmental and food safety aspects. A construct similarity concept was defined, considering the biological function of the introduced genes. Factors like environmental and dietary exposure, familiarity with both the crop and the trait as well as the crop biology, were identified as key to inform a construct-based RA process.

  3. Construction of helium engineering demonstration loop (HENDEL M+A) for VHTR

    International Nuclear Information System (INIS)

    Shimomura, Saneaki; Tanaka, Toshiyuki; Nakano, Tadasuke

    1983-01-01

    The mother and adapter sections of the large structural component demonstration test loop, alias Helium Engineering Demonstration Loop, for the multipurpose, high temperature gas-cooled experimental reactor were completed in March, 1982. This facility was constructed by Fuji Electric Co., Ltd. and Kawasaki Heavy Industries Ltd. as the main contractors, and by the cooperation with Mitsubishi Heavy Industries Ltd. and Ishikawajima Harima Heavy Industries Co., Ltd. The HENDEL M+A is the testing facility of the largest scale in the world, which can handle 1000 deg C, 40 kgf/cm 2 G helium at a half flow rate of one core cooling loop of the experimental reactor. With the HENDEL M+A, the demonstration tests of fuel assembly stacks, in-core structures, large flow rate and high temperature equipment are planned. The HENDEL M+A comprises two mother loops, an adapter loop, and common auxiliary systems fon measurement and control (In), refining (Mp), makeup (Mu) and cooling water (Uc). The construction and function of such main equipment as a heater, circulators and internally insulated piping are described. The progress of the construction and the main experience during the construction, the process of operation and the performance are reported. (Kako, I.)

  4. Nanostructured 3D constructs based on chitosan and chondroitin sulphate multilayers for cartilage tissue engineering.

    Directory of Open Access Journals (Sweden)

    Joana M Silva

    Full Text Available Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT and chondroitin sulphate (CS on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered constructs proved to support the attachment and proliferation of bovine chondrocytes (BCH. The technology was transposed to 3D level and CHT/CS multi-layered hierarchical scaffolds were retrieved after paraffin leaching. The obtained nanostructured 3D constructs had a high porosity and water uptake capacity of about 300%. Dynamical mechanical analysis (DMA showed the viscoelastic nature of the scaffolds. Cellular tests were performed with the culture of BCH and multipotent bone marrow derived stromal cells (hMSCs up to 21 days in chondrogenic differentiation media. Together with scanning electronic microscopy analysis, viability tests and DNA quantification, our results clearly showed that cells attached, proliferated and were metabolically active over the entire scaffold. Cartilaginous extracellular matrix (ECM formation was further assessed and results showed that GAG secretion occurred indicating the maintenance of the chondrogenic phenotype and the chondrogenic differentiation of hMSCs.

  5. Nanostructured 3D constructs based on chitosan and chondroitin sulphate multilayers for cartilage tissue engineering.

    Science.gov (United States)

    Silva, Joana M; Georgi, Nicole; Costa, Rui; Sher, Praveen; Reis, Rui L; Van Blitterswijk, Clemens A; Karperien, Marcel; Mano, João F

    2013-01-01

    Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering. Multilayered constructs were formed by depositing the polyelectrolytes chitosan (CHT) and chondroitin sulphate (CS) on either bidimensional glass surfaces or 3D packet of paraffin spheres. 2D CHT/CS multi-layered constructs proved to support the attachment and proliferation of bovine chondrocytes (BCH). The technology was transposed to 3D level and CHT/CS multi-layered hierarchical scaffolds were retrieved after paraffin leaching. The obtained nanostructured 3D constructs had a high porosity and water uptake capacity of about 300%. Dynamical mechanical analysis (DMA) showed the viscoelastic nature of the scaffolds. Cellular tests were performed with the culture of BCH and multipotent bone marrow derived stromal cells (hMSCs) up to 21 days in chondrogenic differentiation media. Together with scanning electronic microscopy analysis, viability tests and DNA quantification, our results clearly showed that cells attached, proliferated and were metabolically active over the entire scaffold. Cartilaginous extracellular matrix (ECM) formation was further assessed and results showed that GAG secretion occurred indicating the maintenance of the chondrogenic phenotype and the chondrogenic differentiation of hMSCs.

  6. Savannah River Plant engineering, design, and construction history of ``S`` projects and other work, January 1961--December 1964. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1970-03-01

    The work described in this volume of ``S`` Projects History is an extension of the type of work described in Volume I. E.I. du Pont de flemours & Company had entered into Contract AT (07-2)-l with the United States Atomic Energy Commission to develop, design, construct, install, and operate facilities to produce heavy water, fissionable materials, and related products. Under this contract,, Du Pont constructed and operated the Savannah River Plant. The engineering, design, and construction for most of the larger ``S`` projects was performed by the Engineering DeDartment. For some of the large and many of the smaller projects the Engineering Department was responsible only for the construction because the Atomic Energy Division (AED) of the Explosives Department handled the other phases. The Engineering Department Costruction Division also performed the physical work for many of the plant work orders. This volume includes a general description of the Du Pont Engineering Department activities pertaining to the engineering, design, and construction of the ``S`` projects at the Savannah River Plant; brief summaries of the projects and principal work requests; and supplementary informaticn on a few subjects in Volume I for which final data was not available at the closing date. Projects and other plant engineering work which were handled entirely by the Explosives Department -- AED are not included in this history.

  7. NTRCI Legacy Engine Research and Development Project Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Smith-Holbert, Connie [National Transportation Research Center, Inc., Knoxville, TN (United States); Petrolino, Joseph [National Transportation Research Center, Inc., Knoxville, TN (United States); Watkins, Bart [Power Source Technologies Inc., Corvallis, OR (United States); Irick, David [Power Source Technologies Inc., Corvallis, OR (United States)

    2011-12-31

    The Legacy engine is a completely new design, transitional diesel engine, replacing the reciprocating engine with a rotary engine. The Legacy engine offers significant advances over conventional internal combustion engines in 1) power to weight ratio; 2) multiple fuel acceptance; 3) fuel economy; and 4) environmental compliance. These advances are achieved through a combination of innovative design geometry, rotary motion, aspiration simplicity, and manufacturing/part simplicity. The key technical challenge to the Legacy engine's commercialization, and the focus of this project, was the development of a viable roton tip seal. The PST concept for the roton tip seal was developed into a manufacturable design. The design was evaluated using a custom designed and fabricated seal test fixture and further refined. This design was incorporated into the GEN2.5A prototype and tested for achievable compression pressure. The Decision Point at the end of Phase 1 of the project (described below) was to further optimize the existing tip seal design. Enhancements to the tip seal design were incorporated into the GEN2.5B prototype and tested and evaluated using the iterative research strategy described below. Compression pressures adequate for compression ignition of diesel fuel were achieved, although not consistently in all combustion volumes. The variation in compression pressures was characterized versus design features. As the roton tip seal performance was improved, results pointed toward inadequate performance of the housing side seals. Enhancement of the housing side seal system was accomplished using a custom designed side seal test fixture. The design enhancements developed with the test fixture were also incorporated into the GEN2.5B prototype and tested and evaluated using the iterative research strategy described below. Finally, to simplify the requirements for the roton tip seals and to enhance the introduction and combustion of fuel, a flush-mount fuel injector

  8. Current and Future Research Directions in Requirements Engineering

    Science.gov (United States)

    Cheng, Betty H. C.; Atlee, Joanne M.

    In this paper, we review current requirements engineering (RE) research and identify future research directions suggested by emerging software needs. First, we overview the state of the art in RE research. The research is considered with respect to technologies developed to address specific requirements tasks, such as elicitation, modeling, and analysis. Such a review enables us to identify mature areas of research, as well as areas that warrant further investigation. Next, we review several strategies for performing and extending RE research results, to help delineate the scope of future research directions. Finally, we highlight what we consider to be the “hot” current and future research topics, which aim to address RE needs for emerging systems of the future.

  9. Advancing Integrated STEM Learning through Engineering Design: Sixth-Grade Students' Design and Construction of Earthquake Resistant Buildings

    Science.gov (United States)

    English, Lyn D.; King, Donna; Smeed, Joanna

    2017-01-01

    As part of a 3-year longitudinal study, 136 sixth-grade students completed an engineering-based problem on earthquakes involving integrated STEM learning. Students employed engineering design processes and STEM disciplinary knowledge to plan, sketch, then construct a building designed to withstand earthquake damage, taking into account a number of…

  10. Towards a portal and search engine to facilitate academic and research collaboration in engineering and education

    Science.gov (United States)

    Bonilla Villarreal, Isaura Nathaly

    While international academic and research collaborations are of great importance at this time, it is not easy to find researchers in the engineering field that publish in languages other than English. Because of this disconnect, there exists a need for a portal to find Who's Who in Engineering Education in the Americas. The objective of this thesis is to built an object-oriented architecture for this proposed portal. The Unified Modeling Language (UML) model developed in this thesis incorporates the basic structure of a social network for academic purposes. Reverse engineering of three social networks portals yielded important aspects of their structures that have been incorporated in the proposed UML model. Furthermore, the present work includes a pattern for academic social networks..

  11. Use of university research reactors to teach control engineering

    International Nuclear Information System (INIS)

    Bernard, J.A.

    1991-01-01

    University research reactors (URRs) have provided generations of students with the opportunity to receive instruction and do hands-on work in reactor dynamics, neutron scattering, health physics, and neutron activation analysis. Given that many URRs are currently converting to programmable control systems, the opportunity now exists to provide a similar learning experience to those studying systems control engineering. That possibility is examined here with emphasis on the need for the inclusion of experiment in control engineering curricula, the type of activities that could be performed, and safety considerations

  12. Japan Atomic Energy Research Institute, Reactor Engineering Division annual report

    International Nuclear Information System (INIS)

    1979-09-01

    Research activities in the Division of Reactor Engineering in fiscal 1978 are described. Works of the Division are development of multi-purpose Very High Temperature Gas Cooled Reactor, fusion reactor engineering, and development of Liquid Metal Fast Breeder Reactor for Power Reactor and Nuclear Fuel Development Corporation. Contents of the report are nuclear data and group constants, theoretical method and code development, integral experiment and analysis, shielding, reactor and nuclear instrumentation, dynamics analysis and control method development, fusion reactor technology, and Committees on Reactor Physics and in Decommissioning of Nuclear Facilities. (author)

  13. A Novel Pulsatile Bioreactor for Mechanical Stimulation of Tissue Engineered Cardiac Constructs

    Directory of Open Access Journals (Sweden)

    Günther Eissner

    2011-07-01

    Full Text Available After myocardial infarction, the implantation of stem cell seeded scaffolds on the ischemic zone represents a promising strategy for restoration of heart function. However, mechanical integrity and functionality of tissue engineered constructs need to be determined prior to implantation. Therefore, in this study a novel pulsatile bioreactor mimicking the myocardial contraction was developed to analyze the behavior of mesenchymal stem cells derived from umbilical cord tissue (UCMSC colonized on titanium-coated polytetrafluorethylene scaffolds to friction stress. The design of the bioreactor enables a simple handling and defined mechanical forces on three seeded scaffolds at physiological conditions. The compact system made of acrylic glass, Teflon®, silicone, and stainless steel allows the comparison of different media, cells and scaffolds. The bioreactor can be gas sterilized and actuated in a standard incubator. Macroscopic observations and pressure-measurements showed a uniformly sinusoidal pulsation, indicating that the bioreactor performed well. Preliminary experiments to determine the adherence rate and morphology of UCMSC after mechanical loadings showed an almost confluent cellular coating without damage on the cell surface. In summary, the bioreactor is an adequate tool for the mechanical stress of seeded scaffolds and offers dynamic stimuli for pre-conditioning of cardiac tissue engineered constructs in vitro.

  14. Pathway Construction in Corynebacterium glutamicum and Strain Engineering To Produce Rare Sugars from Glycerol.

    Science.gov (United States)

    Yang, Jiangang; Zhu, Yueming; Men, Yan; Sun, Shangshang; Zeng, Yan; Zhang, Ying; Sun, Yuanxia; Ma, Yanhe

    2016-12-21

    Rare sugars are valuable natural products widely used in pharmaceutical and food industries. In this study, we expected to synthesize rare ketoses from abundant glycerol using dihydroxyacetone phosphate (DHAP)-dependent aldolases. First, a new glycerol assimilation pathway was constructed to synthesize DHAP. The enzymes which convert glycerol to 3-hydroxypropionaldehyde and l-glyceraldehyde were selected, and their corresponding aldehyde synthesis pathways were constructed in vivo. Four aldol pathways based on different aldolases and phosphorylase were gathered. Next, three pathways were assembled and the resulting strains synthesized 5-deoxypsicose, 5-deoxysorbose, and 5-deoxyfructose from glucose and glycerol and produce l-fructose, l-tagatose, l-sorbose, and l-psicose with glycerol as the only carbon source. To achieve higher product titer and yield, the recombinant strains were further engineered and fermentation conditions were optimized. Fed-batch culture of engineered strains obtained 38.1 g/L 5-deoxypsicose with a yield of 0.91 ± 0.04 mol product per mol of glycerol and synthesized 20.8 g/L l-fructose, 10.3 g/L l-tagatose, 1.2 g/L l-sorbose, and 0.95 g/L l-psicose.

  15. Dam construction as an engineering solution for water supply problem : environmental thrusts

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, A.H. [Alberta Univ., Edmonton, AB (Canada). Dept. of Civil and Environmental Engineering

    2004-09-01

    Water supply management and the potential impacts associated with engineering practices in water supply systems were examined. Global aspects of increasing water demand were presented and compared with populations, urbanization and water demand. Engineering practices in waterworks developments such as dam construction, river intakes, infiltration galleries, wells, boreholes and adits were also discussed. Construction of large dams and the problems associated with damming the rivers were studied as large dams generally have substantial impacts on rivers, watersheds and aquatic ecosystems, leading to the irreversible loss of species populations and ecosystems. These problems include negative impacts on the terrestrial ecosystem, greenhouse gas emissions from reservoirs due to decaying vegetation and carbon inflows from the catchment, changes in flow regimes, trapping of sediments and nutrients behind a dam, blocking migration of aquatic organisms, as well as negative impacts on flood plain ecosystems and fisheries. In addition, a case study, on the environmental impacts associated with damming in Three Gorges Valley in China was presented. 9 refs., 8 figs.

  16. Tensile loading modulates bone marrow stromal cell differentiation and the development of engineered fibrocartilage constructs.

    Science.gov (United States)

    Connelly, John T; Vanderploeg, Eric J; Mouw, Janna K; Wilson, Christopher G; Levenston, Marc E

    2010-06-01

    Mesenchymal progenitors such as bone marrow stromal cells (BMSCs) are an attractive cell source for fibrocartilage tissue engineering, but the types or combinations of signals required to promote fibrochondrocyte-specific differentiation remain unclear. The present study investigated the influences of cyclic tensile loading on the chondrogenesis of BMSCs and the development of engineered fibrocartilage. Cyclic tensile displacements (10%, 1 Hz) were applied to BMSC-seeded fibrin constructs for short (24 h) or extended (1-2 weeks) periods using a custom loading system. At early stages of chondrogenesis, 24 h of cyclic tension stimulated both protein and proteoglycan synthesis, but at later stages, tension increased protein synthesis only. One week of intermittent cyclic tension significantly increased the total sulfated glycosaminoglycan and collagen contents in the constructs, but these differences were lost after 2 weeks of loading. Constraining the gels during the extended culture periods prevented contraction of the fibrin matrix, induced collagen fiber alignment, and increased sulfated glycosaminoglycan release to the media. Cyclic tension specifically stimulated collagen I mRNA expression and protein synthesis, but had no effect on collagen II, aggrecan, or osteocalcin mRNA levels. Overall, these studies suggest that the combination of chondrogenic stimuli and tensile loading promotes fibrochondrocyte-like differentiation of BMSCs and has the potential to direct fibrocartilage development in vitro.

  17. Tough and flexible CNT-polymeric hybrid scaffolds for engineering cardiac constructs.

    Science.gov (United States)

    Kharaziha, Mahshid; Shin, Su Ryon; Nikkhah, Mehdi; Topkaya, Seda Nur; Masoumi, Nafiseh; Annabi, Nasim; Dokmeci, Mehmet R; Khademhosseini, Ali

    2014-08-01

    In the past few years, a considerable amount of effort has been devoted toward the development of biomimetic scaffolds for cardiac tissue engineering. However, most of the previous scaffolds have been electrically insulating or lacked the structural and mechanical robustness to engineer cardiac tissue constructs with suitable electrophysiological functions. Here, we developed tough and flexible hybrid scaffolds with enhanced electrical properties composed of carbon nanotubes (CNTs) embedded aligned poly(glycerol sebacate):gelatin (PG) electrospun nanofibers. Incorporation of varying concentrations of CNTs from 0 to 1.5% within the PG nanofibrous scaffolds (CNT-PG scaffolds) notably enhanced fiber alignment and improved the electrical conductivity and toughness of the scaffolds while maintaining the viability, retention, alignment, and contractile activities of cardiomyocytes (CMs) seeded on the scaffolds. The resulting CNT-PG scaffolds resulted in stronger spontaneous and synchronous beating behavior (3.5-fold lower excitation threshold and 2.8-fold higher maximum capture rate) compared to those cultured on PG scaffold. Overall, our findings demonstrated that aligned CNT-PG scaffold exhibited superior mechanical properties with enhanced CM beating properties. It is envisioned that the proposed hybrid scaffolds can be useful for generating cardiac tissue constructs with improved organization and maturation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Methods for constructing exact solutions of partial differential equations mathematical and analytical techniques with applications to engineering

    CERN Document Server

    Meleshko, Sergey V

    2005-01-01

    Differential equations, especially nonlinear, present the most effective way for describing complex physical processes. Methods for constructing exact solutions of differential equations play an important role in applied mathematics and mechanics. This book aims to provide scientists, engineers and students with an easy-to-follow, but comprehensive, description of the methods for constructing exact solutions of differential equations.

  19. Annual report of the CTR Blanket Engineering research facility in 1996

    International Nuclear Information System (INIS)

    1998-02-01

    This is an annual report of the studies on Controlled Thermo-nuclear Reactor (CTR) Blanket Engineering which have been carried out in the Faculty of Engineering, the University of Tokyo, in FY 1996. This research facility on the CTR Blanket Engineering is located in the Nuclear Engineering Research Laboratory, the Tokai-mura branch of the Faculty of Engineering. (J.P.N.)

  20. Annual report of the CTR Blanket Engineering research facility in 1992

    International Nuclear Information System (INIS)

    1993-08-01

    This is an annual report of the studies on Controlled Thermo-nuclear Reactor (CTR) Blanket Engineering which have been carried out in the Faculty of Engineering, the University of Tokyo, in FY 1992. This research facility on the CTR Blanket Engineering is located in the Nuclear Engineering Research Laboratory, the Tokai-mura branch of the Faculty of Engineering. (J.P.N.)

  1. Annual report of the CTR Blanket Engineering research facility in 1994

    International Nuclear Information System (INIS)

    1995-09-01

    This is an annual report of the studies on Controlled Thermo-nuclear Reactor(CTR) Blanket Engineering which have been carried out in the Faculty of Engineering, the University of Tokyo, in FY 1994. This research facility on the CTR Blanket Engineering is located in the Nuclear Engineering Research Laboratory, the Tokai-mura branch of the Faculty of Engineering. (author)

  2. Annual report of the CTR blanket engineering research facility in 1993

    International Nuclear Information System (INIS)

    1994-08-01

    This is an annual report of the studies on Controlled Thermo-nuclear Reactor (CTR) Blanket Engineering which have been carried out in the Faculty of Engineering, the University of Tokyo, in FY 1993. This research facility on the CTR Blanket Engineering is located in the Nuclear Engineering Research Laboratory, the Tokai-mura branch of the Faculty of Engineering. (author)

  3. Active learning about research methodology in engineering education

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    Research methodology and theory of science have become important teaching subjects en engineering education as well as in higher education in general. This is rooted in the transition to a knowledge society. Today, it is argued by many that we are well on the way to an era beyond modernity...... of science if often not favored subjects by engineering students, who tend to find the subjects abstract. Thus, the students are often very engaged in the subjects, nor are textbooks or teaching very engaging. This poster asks how we can promote active learning in research methodology and theory of science...... and the sort of industrial economy that came with it. Whatever else the new era brings – the globalization of risks, environmental problems, new technologies, etc. – knowledge and the ability to seek, produce, apply and transform knowledge is of huge importance. However, research methodology and theory...

  4. Design, engineering, and construction of photosynthetic microbial cell factories for renewable solar fuel production.

    Science.gov (United States)

    Lindblad, Peter; Lindberg, Pia; Oliveira, Paulo; Stensjö, Karin; Heidorn, Thorsten

    2012-01-01

    There is an urgent need to develop sustainable solutions to convert solar energy into energy carriers used in the society. In addition to solar cells generating electricity, there are several options to generate solar fuels. This paper outlines and discusses the design and engineering of photosynthetic microbial systems for the generation of renewable solar fuels, with a focus on cyanobacteria. Cyanobacteria are prokaryotic microorganisms with the same type of photosynthesis as higher plants. Native and engineered cyanobacteria have been used by us and others as model systems to examine, demonstrate, and develop photobiological H(2) production. More recently, the production of carbon-containing solar fuels like ethanol, butanol, and isoprene have been demonstrated. We are using a synthetic biology approach to develop efficient photosynthetic microbial cell factories for direct generation of biofuels from solar energy. Present progress and advances in the design, engineering, and construction of such cyanobacterial cells for the generation of a portfolio of solar fuels, e.g., hydrogen, alcohols, and isoprene, are presented and discussed. Possibilities and challenges when introducing and using synthetic biology are highlighted.

  5. Design, Engineering, and Construction of Photosynthetic Microbial Cell Factories for Renewable Solar Fuel Production

    Energy Technology Data Exchange (ETDEWEB)

    Lindblad, Peter; Lindberg, Pia; Stensjoe, Karin (Photochemistry and Molecular Science, Dept. of Chemistry-Aangstroem Laboratory, Uppsala Univ., Uppsala (Sweden)), E-mail: Peter.Lindblad@kemi.uu.se; Oliveira, Paulo (Instituto de Biologia Molecular e Celular, Porto (Portugal)); Heidorn, Thorsten (Bioforsk-Norwegian Inst. for Agricultural and Environmental Research, Aas Oslo, (Norway))

    2012-03-15

    There is an urgent need to develop sustainable solutions to convert solar energy into energy carriers used in the society. In addition to solar cells generating electricity, there are several options to generate solar fuels. This paper outlines and discusses the design and engineering of photosynthetic microbial systems for the generation of renewable solar fuels, with a focus on cyanobacteria. Cyanobacteria are prokaryotic microorganisms with the same type of photosynthesis as higher plants. Native and engineered cyanobacteria have been used by us and others as model systems to examine, demonstrate, and develop photobiological H{sub 2} production. More recently, the production of carbon-containing solar fuels like ethanol, butanol, and isoprene have been demonstrated. We are using a synthetic biology approach to develop efficient photosynthetic microbial cell factories for direct generation of biofuels from solar energy. Present progress and advances in the design, engineering, and construction of such cyanobacterial cells for the generation of a portfolio of solar fuels, e.g., hydrogen, alcohols, and isoprene, are presented and discussed. Possibilities and challenges when introducing and using synthetic biology are highlighted

  6. CONSTRUCTION OF AN INSTRUMENT OF VOCATIONAL PREFERENCES FOR ENGINEERING CAREERS: THE IPVI INVENTORY

    Directory of Open Access Journals (Sweden)

    CARLOS E. ZERPA

    2007-11-01

    Full Text Available The main purpose of this work is to present the construction process and the most important psychometrical properties of a vocational preference test which we hope will prove to be a useful tool to help future engineering students make vocational decisions. The test may help to clarify the possible options within the general areas of study, according to the different specializations available. Originally, the IPVI included 14 subscales that corresponded to thesame number of engineering specializations offered in a Venezuelan university. The factorial structure underlying local data was studied through a sample of 174 engineering students, males and females, between 16 and 24 years old, via a factorial analysis of the consistency of the instrument and each subscale through Cronbach Alpha coefficient. An analysis of the main components was carried out and a new version of seven categories was made which was administrated to a sample of 456 students of both sexes, of ages between 16 and 25, from an important Venezuelan higher education institution. The factors found support the proposed dimensions in the second study. Some psychometric properties and implications for vocational counseling will be discussed.

  7. An exploration of the biomedical optics course construction of undergraduate biomedical engineering program in medical colleges

    Science.gov (United States)

    Guo, Shijun; Lyu, Jie; Zhang, Peiming

    2017-08-01

    In this paper, the teaching goals, teaching contents and teaching methods in biomedical optics course construction are discussed. From the dimension of teaching goals, students should master the principle of optical inspection on the human body, diagnosis and treatment of methodology and instruments, through the study of the theory and practice of this course, and can utilize biomedical optics methods to solve practical problems in the clinical medical engineering practice. From the dimension of teaching contents, based on the characteristics of biomedical engineering in medical colleges, the organic integration of engineering aspects, medical optical instruments, and biomedical aspects dispersed in human anatomy, human physiology, clinical medicine fundamental related to the biomedical optics is build. Noninvasive measurement of the human body composition and noninvasive optical imaging of the human body were taken as actual problems in biomedical optics fields. Typical medical applications such as eye optics and laser medicine were also integrated into the theory and practice teaching. From the dimension of teaching methods, referencing to organ-system based medical teaching mode, optical principle and instrument principle were taught by teachers from school of medical instruments, and the histological characteristics and clinical actual need in areas such as digestive diseases and urinary surgery were taught by teachers from school of basic medicine or clinical medicine of medical colleges. Furthermore, clinical application guidance would be provided by physician and surgeons in hospitals.

  8. Research on the Fault Coefficient in Complex Electrical Engineering

    Directory of Open Access Journals (Sweden)

    Yi Sun

    2015-08-01

    Full Text Available Fault detection and isolation in a complex system are research hotspots and frontier problems in the reliability engineering field. Fault identification can be regarded as a procedure of excavating key characteristics from massive failure data, then classifying and identifying fault samples. In this paper, based on the fundamental of feature extraction about the fault coefficient, we will discuss the fault coefficient feature in complex electrical engineering in detail. For general fault types in a complex power system, even if there is a strong white Gaussian stochastic interference, the fault coefficient feature is still accurate and reliable. The results about comparative analysis of noise influence will also demonstrate the strong anti-interference ability and great redundancy of the fault coefficient feature in complex electrical engineering.

  9. Research and development related to the services engineering

    International Nuclear Information System (INIS)

    Rembado, J. L.

    2000-01-01

    In the present paper it is clarified what is understood by the expression R and D, Research and Development in the Servicie Engineering's which support the nuclear power plants exploitation, being more appropriated to talk about Innovation and Technological Development. In this paper it is analysed the need to have an innovation as per the marketing needs and to have a technological development to maintain an independence to let us to keep and increase the company's activity. It is described how the Services Engineering's with technological development turn to equipment suppliers which can be supplied to the nuclear sector as well as to other industrial sectors. Finally, it is described the innovation and technological development evolution, the technological polities objectives and the action lines of Tecnatom, S. A. as a Services Engineering's. (Author)

  10. Nuclear science and engineering education at a university research reactor

    International Nuclear Information System (INIS)

    Loveland, W.

    1990-01-01

    The research and teaching operations of the Nuclear Chemistry Division of the Dept. of Chemistry and the Dept. of Nuclear Engineering are housed at the Oregon State University Radiation Center. This facility which includes a 1.1 MW TRIGA reactor was used for 53 classes from a number of different academic departments last year. About one-half of these classes used the reactor and ∼25% of the reactor's 45 hour week was devoted to teaching. Descriptions will be given of reactor-oriented instructional programs in nuclear engineering, radiation health and nuclear chemistry. In nuclear chemistry, classes in (a) nuclear chemistry for nuclear engineers, (b) radiotracer methods, (c) elementary and advanced activation analysis, and (d) advanced nuclear instrumentation will be described in detail. The use of the facility to promote general nuclear literacy among college students, high school and grade school students and the general population will also be covered

  11. Engineering and training simulators: A combined approach for nuclear plant construction projects

    International Nuclear Information System (INIS)

    Harnois, Olivier; Gain, Pascal; Bartak, Jan; Gathmann, Ralf

    2007-01-01

    Full text: Simulation technologies have always been widely used on nuclear applications, but with a clear division between engineering application, using highly validated code run in batch mode, and training purpose where real time computation is a mandatory requirement. Thanks to the flexibility of modern simulation technology and the increased performance of computers, it becomes now possible to develop Nuclear Power plant simulators that can be used both for engineering and training purposes. In the last years, the revival of nuclear industry raised a number of new construction or plant finishing projects in which the application of this combined approach would result in decisive improvement on plant construction lead times, better project control and cost optimizations. The simulator development is to be executed in a step-wise approach, scheduled in parallel with the plant design and construction phases. During a first step, the simulator will model the plant nuclear island systems plus the corresponding instrumentation and control, specific malfunctions and local commands. It can then be used for engineering activities defining and validating the plant operating strategies in case of incidents or accidents. The Simulator executive Station and Operator Station will be in prototype version with an interface imagery enabling monitoring and control of the simulator. Availability of such simulation platform leads to a significant increase in efficiency of the engineering works, the possibility to validate basic design hypotheses and detect defects and conflicts early. The second phase will consist in the fully detailed simulation of Main Control Room plant supervision and control MMI, taking into account I and C control loops detailed design improvement, while having sufficient fidelity in order to be suitable for the future operator training. Its use will enable the engineering units not only to specify and validate normal, incident and accident detailed plant

  12. Research reactor usage at the Idaho National Engineering Laboratory in support of university research and education

    International Nuclear Information System (INIS)

    Woodall, D.M.; Dolan, T.J.; Stephens, A.G.

    1990-01-01

    The Idaho National Engineering Laboratory is a US Department of Energy laboratory which has a substantial history of research and development in nuclear reactor technologies. There are a number of available nuclear reactor facilities which have been incorporated into the research and training needs of university nuclear engineering programs. This paper addresses the utilization of the Advanced Reactivity Measurement Facility (ARMF) and the Coupled Fast Reactivity Measurement Facility (CFRMF) for thesis and dissertation research in the PhD program in Nuclear Science and Engineering by the University of Idaho and Idaho State University. Other reactors at the INEL are also being used by various members of the academic community for thesis and dissertation research, as well as for research to advance the state of knowledge in innovative nuclear technologies, with the EBR-II facility playing an essential role in liquid metal breeder reactor research. 3 refs

  13. NASA Space Engineering Research Center for VLSI systems design

    Science.gov (United States)

    1991-01-01

    This annual review reports the center's activities and findings on very large scale integration (VLSI) systems design for 1990, including project status, financial support, publications, the NASA Space Engineering Research Center (SERC) Symposium on VLSI Design, research results, and outreach programs. Processor chips completed or under development are listed. Research results summarized include a design technique to harden complementary metal oxide semiconductors (CMOS) memory circuits against single event upset (SEU); improved circuit design procedures; and advances in computer aided design (CAD), communications, computer architectures, and reliability design. Also described is a high school teacher program that exposes teachers to the fundamentals of digital logic design.

  14. Towards Multi-Method Research Approach in Empirical Software Engineering

    Science.gov (United States)

    Mandić, Vladimir; Markkula, Jouni; Oivo, Markku

    This paper presents results of a literature analysis on Empirical Research Approaches in Software Engineering (SE). The analysis explores reasons why traditional methods, such as statistical hypothesis testing and experiment replication are weakly utilized in the field of SE. It appears that basic assumptions and preconditions of the traditional methods are contradicting the actual situation in the SE. Furthermore, we have identified main issues that should be considered by the researcher when selecting the research approach. In virtue of reasons for weak utilization of traditional methods we propose stronger use of Multi-Method approach with Pragmatism as the philosophical standpoint.

  15. The perspectives of research in the construction field in Romania during the 2014-2020 period

    OpenAIRE

    Mihai VRABIE; Sergiu-Andrei BĂETU

    2013-01-01

    The construction field represents an important part of the Romanian economy (and of UE), with a strong social impact on the quality of citizen life. Naturally, the research from the construction field should be a priority in research and innovation activity. However, the research programs recently launched (Horizon 2020, from EU, and the Strategy of Research and Innovation 2014-2020 in Romania), don’t mention the construction field as an explicit priority. Under these conditions, we can speak...

  16. Development of support tools for efficient construction of dynamic simulation program for engineering systems

    International Nuclear Information System (INIS)

    Gofuku, Akio

    1993-01-01

    In this study, two support tools are developed for construction of a dynamic simulation program for engineering systems (especially nuclear systems) by combining software modules. These are (1) a sub-system to support the module selection suitable for dynamic simulation and (2) a graphical user interface to support visual construction of simulation programs. The support tools are designed to be independent on the conception of software modules (data communication methods between modules). In the module selection sub-system of item 1, a module is characterized beforehand by keywords for several criteria. The similarity between the characteristic of requested module by users and that of registered modules in the module library is estimated by a weighted average of similarity indexes for criteria. In the module selection sub-system, the weights are flexibly extracted from users by applying the analytic hierarchy process. The graphical user interface helps users to specify both calling order of modules and data transfer between two modules. The availability of the support tools is evaluated by several sample problems of module selection and dynamic simulation model construction. The support tools will be a strong tool for the efficient usage of software modules. (author)

  17. Experimental researches about the influence of the additives for engine oils upon the work of the engine

    International Nuclear Information System (INIS)

    Dimitrovski, Mile; Mucevski, Kiril

    2003-01-01

    In this paper an attempt to get some cognitions about the influence of the additives for engine oils upon the working parameters of the internal combustion engines is made. During the experimental researches the changes of the basic parameters which determine the work of the engine, such as: the pressure of compression, the noise, the vibrations, the friction of the engine mechanism, the internal cleanliness of the engine and similar, were observed. It was conclude that the use of additives into the engine oil resulted with smoother work of the engine and cleaner exhausted as well. (Author)

  18. Principal provisions of engineering and geological survey methodology in designing and construction of underground laboratory as a part of facility of RW underground isolation

    International Nuclear Information System (INIS)

    Prokopova, O.A.

    2006-01-01

    The most critical moment is the choice of a site for radioactive waste geological repository. Here the role of engineering and geological prospecting as a basis for the construction of a facility for underground isolation appears especially important; it is followed by finding a suitable area and subsequent allocation of the site and facility construction sites. The decision on the selection of construction site for the underground repository is taken by the principle 'descent from the general to the particular', which is a continuous process with the observance of stages in research for the design and exploration work. Each stage of research is typified by specific scale and methods of geological and geophysical studies and scientific research to be fulfilled in scopes sufficient for solution of basic problems for the designing. (author)

  19. 3D Printing of Tissue Engineered Constructs for in vitro Modeling of Disease Progression and Drug Screening

    Science.gov (United States)

    Vanderburgh, Joseph; Sterling, Julie A.

    2016-01-01

    2D cell culture and preclinical animal models have traditionally been implemented for investigating the underlying cellular mechanisms of human disease progression. However, the increasing significance of 3D versus 2D cell culture has initiated a new era in cell culture research in which 3D in vitro models are emerging as a bridge between traditional 2D cell culture and in vivo animal models. Additive manufacturing (AM, also known as 3D printing), defined as the layer-by-layer fabrication of parts directed by digital information from a 3D computer-aided design (CAD) file, offers the advantages of simultaneous rapid prototyping and biofunctionalization as well as the precise placement of cells and extracellular matrix with high resolution. In this review, we highlight recent advances in 3D printing of tissue engineered constructs (TECs) that recapitulate the physical and cellular properties of the tissue microenvironment for investigating mechanisms of disease progression and for screening drugs. PMID:27169894

  20. Management and integration of engineering and construction activities: Lessons learned from the AP1000R nuclear power plant China project

    International Nuclear Information System (INIS)

    McCullough, M. C.; Ebeling-Koning, D.; Evans, M. C.

    2012-01-01

    The lessons learned during the early phase of design engineering and construction activities for the AP1000 China Project can be applied to any project involving multiple disciplines and multiple organizations. Implementation of a first-of-a-kind design to directly support construction activities utilizing resources assigned to design development and design delivery creates challenges with prioritization of activities, successful closure of issues, and communication between site organizations and the home office. To ensure successful implementation, teams were assigned and developed to directly support construction activities including prioritization of activities, site communication and ensuring closure of site emergent issues. By developing these teams, the organization is better suited to meet the demands of the construction schedule while continuing with design evolution of a standard plant and engineering delivery for multiple projects. For a successful project, proper resource utilization and prioritization are key for overcoming obstacles and ensuring success of the engineering organization. (authors)