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Sample records for con gated-spect experiencia

  1. Rapid gated Thallium-201 perfusion SPECT - clinically feasible?

    International Nuclear Information System (INIS)

    Wadhwa, S.S.; Mansberg, R.; Fernandes, V.B.; Wilkinson, D.; Abatti, D.

    1998-01-01

    Full text: Standard dose energy window optimised Thallium-201 (Tl-201) SPECT has about half the counts of a standard dose from Technetium-99m Sestamibi (Tc99m-Mibi) gated perfusion SPECT. This study investigates the clinical feasibility of rapid energy window optimised Tl-201 gated perfusion SPECT (gated-TI) and compares quantitative left ventricular ejection fraction (LVEF) and visually assessed image quality for wall motion and thickening to analogous values obtained from Tc99m-Mibi gated perfusion SPECT (gated - mibi). Methods: We studied 60 patients with a rest gated Tl-201 SPECT (100 MBq, 77KeV peak, 34% window, 20 sec/projection) followed by a post stress gated Sestamibi SPECT (1GBq, 140KeV, 20% window, 20 sec/projection) separate dual isotope protocol. LVEF quantitation was performed using commercially available software (SPECTEF, General Electric). Visual grading of image quality for wall thickening and motion was performed using a three-point scale (excellent, good and poor). Results: LVEF for gated Tl-201 SPECT was 59.6 ± 12.0% (Mean ± SD). LVEF for gated Sestamibi SPECT was 60.4 ±11.4% (Mean ± SD). These were not significantly different (P=0.27, T-Test). There was good correlation (r=0.9) between gated-TI and gated-mibi LVEF values. The quality of gated-Tl images was ranked as excellent, good and poor in 12, 50 and 38% of the patients respectively. Image quality was better in gated-mibi SPECT, with ratings of 12, 62 and 26% respectively. Conclusion: Rapid gated Thallium-201 acquisition with energy window optimisation can be effectively performed on majority of patients and offers the opportunity to assess not only myocardial perfusion and function, as with Technetium based agents, but also viability using a single day one isotope protocol

  2. Reference Range of Functional Data of Gated Myocardial Perfusion SPECT by Quantitative Gated SPECT of Cedars-Sinai and 4D-MSPECT of Michigan University

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Do Young; Kim, Moo Hyun; Kim, Young Dae [College of Medicine, Univ. of Donga, Pusan (Korea, Republic of)

    2003-07-01

    Various programs have been developed for gating of myocardial perfusion SPECT. Among the those program, the most popular program is the Quantitative Gated SPECT (QGS)? developed by Cedars-Sinai hospital and most recently released program is 4D-MSPECT? developed by university of Michigan. It is important to know the reference range of the functional data of gated myocardial perfusion SPECT because it is necessary to determine abnormality of individual patient and echocardiographic data is different from those of gated SPECT. Tc-99m MIBI gated myocardial perfusion SPECT image was reconstructed by dual head gamma camera (Siemens, BCAM, esoft) as routine procedure and analyzed using QGS? and 4D-MSPECT? program. All patients (M: F=9: 18, Age 69{+-}9 yrs) showed normal myocardial perfusion. The patients with following characteristics were excluded: previous angina or MI history, ECG change with Q wave or ST-T change, diabetes melitius, hypercholesterolemia, typical chest pain, hypertension and cardiomyopathy. Pre-test likelihood of all patients was low. (1) In stress gated SPECT by QGS?, EDV was 73{+-}25 ml, ESV 25{+-}14 ml, EF 67{+-}11 % and area of first frame of gating 106.4{+-}21cm{sup 2}. In rest gated SPECT, EDV was 76{+-}26 ml, ESV 27{+-}15 ml, EF 66{+-}12 and area of first frame of gating 108{+-}20cm{sup 2}. (2) In stress gated SPECT by 4D-MSPECT?, EDV was 76{+-}28 ml, ESV 23{+-}16 ml, EF 72{+-}11 %, mass 115{+-}24 g and ungated volume 42{+-}15 ml. In rest gated SPECT, EDV was 75{+-}27 ml, ESV 23{+-}12 ml, EF 71{+-}9%, mass 113{+-}25g and ungate dvolume 42{+-}15 ml, (3) s-EDV, s-EF, r-ESV and r-EF were significantly different between QGS? and 4D-MSPECT? (each p=0.016, p<0.001. p=0.003 and p=0.001). We determined the normal reference range of functional parameters by QGS? and 4D-MSPECT? program to diagnose individually the abnormality of patients. And the reference ranges have to adopted to be patients by each specific gating program.

  3. Clinical evaluation of the Tl-201 ECG-gated myocardial SPECT

    International Nuclear Information System (INIS)

    Mochizuki, Teruhito

    1989-01-01

    In order to evaluate the clinical usefulness of the Tl-201 ECG-gated myocardial single photon emission computed tomography (SPECT), we compared the wall motion and the grade of the Tl-201 uptake of the ECG-gated myocardial SPECT with the wall motion of the ECG-gated blood pool SPECT. Materials were 87 patients of 50 old myocardial infarctions (OMIs), 19 hypertrophic cardiomyopathies (HCMs), 2 dilated cardiomyopathies (DCMs) and 16 others. After intravenous injection of 111-185 MBq (3-5 mCi) of Tl-201 at rest, the projection data were acquired using a rotating gamma-camera through 180deg, from RAO 45deg in 24 directions, each of which consisted of 80-100 beats. For the reconstruction of ED, ES and non-gated images, R-R interval was divided into about 20 (18-22) fractions. In 348 regions of interest (anterior, septal, lateral and inferior wall) in 87 cases, wall motion and the Tl-201 uptake were evaluated to three grades (normal, hypokinesis and akinesis; normal, low and defect, respectively), which were compared with the wall motion of the ECG-gated blood pool SPECT. The wall motion and the grade of the Tl-201 uptake of the ECG-gated myocardial SPECT correlated well with the wall motion of the ECG-gated blood pool SPECT (96.6% and 87.9%, respectively). In conclusion, the ECG-gated myocardial SPECT can provide clear perfusion images and is a very useful diagnostic strategy to evaluate the regional wall motion and perfusion simultaneously. (author)

  4. Implementation of angular response function modeling in SPECT simulations with GATE

    International Nuclear Information System (INIS)

    Descourt, P; Visvikis, D; Carlier, T; Bardies, M; Du, Y; Song, X; Frey, E C; Tsui, B M W; Buvat, I

    2010-01-01

    Among Monte Carlo simulation codes in medical imaging, the GATE simulation platform is widely used today given its flexibility and accuracy, despite long run times, which in SPECT simulations are mostly spent in tracking photons through the collimators. In this work, a tabulated model of the collimator/detector response was implemented within the GATE framework to significantly reduce the simulation times in SPECT. This implementation uses the angular response function (ARF) model. The performance of the implemented ARF approach has been compared to standard SPECT GATE simulations in terms of the ARF tables' accuracy, overall SPECT system performance and run times. Considering the simulation of the Siemens Symbia T SPECT system using high-energy collimators, differences of less than 1% were measured between the ARF-based and the standard GATE-based simulations, while considering the same noise level in the projections, acceleration factors of up to 180 were obtained when simulating a planar 364 keV source seen with the same SPECT system. The ARF-based and the standard GATE simulation results also agreed very well when considering a four-head SPECT simulation of a realistic Jaszczak phantom filled with iodine-131, with a resulting acceleration factor of 100. In conclusion, the implementation of an ARF-based model of collimator/detector response for SPECT simulations within GATE significantly reduces the simulation run times without compromising accuracy. (note)

  5. Implementation of angular response function modeling in SPECT simulations with GATE

    Energy Technology Data Exchange (ETDEWEB)

    Descourt, P; Visvikis, D [INSERM, U650, LaTIM, IFR SclnBioS, Universite de Brest, CHU Brest, Brest, F-29200 (France); Carlier, T; Bardies, M [CRCNA INSERM U892, Nantes (France); Du, Y; Song, X; Frey, E C; Tsui, B M W [Department of Radiology, J Hopkins University, Baltimore, MD (United States); Buvat, I, E-mail: dimitris@univ-brest.f [IMNC-UMR 8165 CNRS Universites Paris 7 et Paris 11, Orsay (France)

    2010-05-07

    Among Monte Carlo simulation codes in medical imaging, the GATE simulation platform is widely used today given its flexibility and accuracy, despite long run times, which in SPECT simulations are mostly spent in tracking photons through the collimators. In this work, a tabulated model of the collimator/detector response was implemented within the GATE framework to significantly reduce the simulation times in SPECT. This implementation uses the angular response function (ARF) model. The performance of the implemented ARF approach has been compared to standard SPECT GATE simulations in terms of the ARF tables' accuracy, overall SPECT system performance and run times. Considering the simulation of the Siemens Symbia T SPECT system using high-energy collimators, differences of less than 1% were measured between the ARF-based and the standard GATE-based simulations, while considering the same noise level in the projections, acceleration factors of up to 180 were obtained when simulating a planar 364 keV source seen with the same SPECT system. The ARF-based and the standard GATE simulation results also agreed very well when considering a four-head SPECT simulation of a realistic Jaszczak phantom filled with iodine-131, with a resulting acceleration factor of 100. In conclusion, the implementation of an ARF-based model of collimator/detector response for SPECT simulations within GATE significantly reduces the simulation run times without compromising accuracy. (note)

  6. Experiencias de haber crecido con un padre/madre con trastorno mental severo (TMS)

    OpenAIRE

    Vivanco B, Gabriela; Grandón F, Pamela

    2016-01-01

    Introducción. La experiencia de vivir con personas que presentan un Trastorno Mental Severo (TMS) es difícil para las familias, en especial para los hijos quienes han sido poco estudiados. El objetivo de la investigación fue conocer cómo la experiencia de haber vivido con un padre o madre con un trastorno mental severo influyó en la infancia, adolescencia y adultez joven de sus hijos e hijas. Método. Se analizan las experiencias de convivencia con un padre/madre con TMS en 10 hijos (6 hombres...

  7. Evaluation of left ventricular function using electrocardiographically gated myocardial SPECT with (123)I-labeled fatty acid analog.

    Science.gov (United States)

    Nanasato, M; Ando, A; Isobe, S; Nonokawa, M; Hirayama, H; Tsuboi, N; Ito, T; Hirai, M; Yokota, M; Saito, H

    2001-12-01

    Electrocardiographically (ECG) gated myocardial SPECT with (99m)Tc-tetrofosmin has been used widely to assess left ventricular (LV) function. However, the accuracy of variables using ECG gated myocardial SPECT with beta-methyl-p-(123)I-iodophenylpentadecanoic acid (BMIPP) has not been well defined. Thirty-six patients (29 men, 7 women; mean age, 61.6 +/- 15.6 y) with ischemic heart disease underwent ECG gated myocardial SPECT with (123)I-BMIPP and with (99m)Tc-tetrofosmin and left ventriculography (LVG) within 1 wk. LV ejection fraction (LVEF), LV end-diastolic volume (LVEDV), and LV end-systolic volume (LVESV) were determined on gated SPECT using commercially available software for automatic data analysis. These volume-related items on LVG were calculated with an area-length method and were estimated by 2 independent observers to evaluate interobserver validity. The regional wall motion with these methods was assessed visually. LVEF was 41.1% +/- 12.5% on gated SPECT with (123)I-BMIPP, 44.5% +/- 13.1% on gated SPECT with (99m)Tc-tetrofosmin, and 46.0% +/- 12.7% on LVG. Global LV function and regional wall motion between both gated SPECT procedures had excellent correlation (LVEF, r = 0.943; LVEDV, r = 0.934; LVESV, r = 0.952; regional wall motion, kappa = 0.92). However, the correlations of global LV function and regional wall motion between each gated SPECT and LVG were significantly lower. Gated SPECT with (123)I-BMIPP showed the same interobserver validity as gated SPECT with (99m)Tc-tetrofosmin. Gated SPECT with (123)I-BMIPP provides high accuracy with regard to LV function and is sufficiently applicable for use in clinical SPECT. This technique can simultaneously reveal myocardial fatty acid metabolism and LV function, which may be useful to evaluate various cardiac diseases.

  8. Methods of gated-blood-pool-spect data processing

    International Nuclear Information System (INIS)

    Kosa, I.; Mester, J.; Tanaka, M.; Csernay, L.; Mate, E.; Szasz, K.

    1991-01-01

    Three techniques of gated SPECT were evaluated. The methods of Integral SPECT (ISPECT), enddyastole-endsystole SPECT (ED-ES SPECT) and Fourier SPECT were adapted and developed on the Hungarian nuclear medicine data processing system microSEGAMS. The methods are based on data reduction before back projection which results in processing times acceptable for the clinical routine. The clinical performance of the introduced techniques was tested in 10 patients with old posterior myocardial infarction and in 5 patients without cardiac disease. The left ventricular ejection faction determined by ISPECT correlated well with the planar values. The correlation coefficient was 0.89. The correlation coefficient of EF values determined by ED-ES SPECT and planar radionuclide ventriculography was lower (0.70). For the identification of left ventricular wall motion abnormalities ED-ES SPECT and Fourier SPECT exhibited a favourable performance, but ISPECT only moderate suitability. In the detection of regional phase delay Fourier-SPECT demonstrated higher sensitivity than the planar radionuclide ventriculography. (author) 4 refs.; 3 figs.; 2 tabs

  9. Assessment of left ventricular function by 201Tl FCG-gated myocardial SPECT

    International Nuclear Information System (INIS)

    Toba, Masahiro; Ishida, Yoshio; Fukuchi, Kazuki; Fukushima, Kazuhito; Katafuchi, Tetsurou; Hayashida, Kohei; Oka, Hisashi; Takamiya, Makoto

    1999-01-01

    We applied the QGS program for LV function analysis (described by Germano, 1995) to a 201 Tl SPECT study at rest, and estimated its accuracy. We performed 201 Tl ECG-gated myocardial SPECT in 25 patients with ischemic heart disease under an acquisition time used in the routine 99m Tc ECG-gated SPECT study. The quality of the gated images was visually assessed with a 4-point grading system. LVEDV, LVESV, LVEF determined by the QGS program were compared with those by Simpson's method on biplane LVG in 25 patients. Regional wall motion scores in 7 myocardial segments were assessed on the three-dimensional display created by the QGS program and the cine display of biplane LVG with a 5-point grading system. Wall motion scores obtained by the QGS program were compared with those by LVG. Although 72.0% of 201 Tl ECG-gated SPECT images were fair or poor in image quality, there were good correlations between the values obtained by the QGS program and LVG (LVEDV: r=0.82, LVESV: r=0.88, LVEF: r=0.89). In addition, wall motion scores by the QGS program were correspondent to those by LVG in 77.1% of all 175 myocardial segments. We conclude that the QGS program provides high accuracy in evaluating left ventricular function even from 201 Tl ECG-gated myocardial SPECT data. (author)

  10. Paradoxical motion of interventricular septum on Tc-99m MIBI gated SPECT study

    International Nuclear Information System (INIS)

    Ergun, E.L.; Erbas, B.; Beylergil, V.; Demirturk, O.S.; Pasaoglu, I.

    2004-01-01

    After uncomplicated cardiac surgery, abnormal motion of the interventricular septum is frequently observed. The interventricular septum has often been found to display dyskinetic, or paradoxical motion by echocardiographic studies. This study was undertaken to describe instances of paradoxical motion of interventricular septum on Tc-99m MIBI gated SPECT studies in patients after coronary artery by pass graft surgery. Tc-99m MIBI gated SPECT in conjunction with stress myocardial perfusion SPECT was performed in 18 patients who had history of cardiac bypass graft surgery. Paradoxical motion of the interventricular septum was defined visually from Tc-99m MIBI gated SPECT. Perfusion of the interventricular septum was examined from myocardial perfusion images in the same study. Paradoxical motion of the interventricular septum was observed in 4 patients (22%). The interventricular septum was normally perfused in all patients. It was concluded that paradoxical motion of the interventricular septum in patients who had a history of cardiac by-pass graft surgery is not an uncommon finding and it can be observed with gated SPECT. The exact mechanism of this phenomenon is not well-known. A normal perfusion in interventricular wall helps to discriminate this situation from a real abnormality. (author)

  11. Gated myocardial SPECT using spatial and temporal filtering

    International Nuclear Information System (INIS)

    Hatton, R.L.; Hutton, B.F.; Kyme, A.Z.; Larcos, G.

    2002-01-01

    Full text: Standard protocols for examining myocardial perfusion and motion defects involve the use of gated SPECT images, and a composite of the gated frames. This study examines the usefulness of extracting one or a combination of frames from the gated image to assess perfusion, and whether the addition of a temporal filter to the gated image improves signal to noise. Choice of the most appropriate frame was also considered. Sixteen and eight frame gated SPECT studies were simulated using the dynamic NURBS-based cardiac torso (NCAT) phantom. Variously sized perfusion defects were included in the inferior wall to assess contrast to normal tissue. Scatter and attenuation were not included. Butterworth spatial cutoff frequencies were varied to establish the most appropriate combination of temporal/spatial filters to reduce noise and retain contrast in the images. The 16 frame data produced higher ejection fraction across all spatial filter cutoffs, and generally was unaffected by temporal filtering. Temporal filtering reduced the noise in a uniform liver region in the gated images to within 25% of the composite image noise. The lesion extent and contrast were greater in the end-diastolic frames compared to end-systolic and mid-cycle frames. In conclusion, by using a temporally filtered end-diastolic image from the gated sequence, a favourable balance between noise and contrast can be achieved. Work is progress to confirm these findings in the clinical situation. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  12. 'Motion frozen' quantification and display of myocardial perfusion gated SPECT

    International Nuclear Information System (INIS)

    Slomka, P.J.; Hurwitz, G.A.; Baddredine, M.; Baranowski, J.; Aladl, U.E.

    2002-01-01

    Aim: Gated SPECT imaging incorporates both functional and perfusion information of the left ventricle (LV). However perfusion data is confounded by the effect of ventricular motion. Most existing quantification paradigms simply add all gated frames and then proceed to extract the perfusion information from static images, discarding the effects of cardiac motion. In an attempt to improve the reliability and accuracy of cardiac SPECT quantification we propose to eliminate the LV motion prior to the perfusion quantification via automated image warping algorithm. Methods: A pilot series of 14 male and 11 female gated stress SPECT images acquired with 8 time bins have been co-registered to the coordinates of the 3D normal templates. Subsequently the LV endo and epi-cardial 3D points (300-500) were identified on end-systolic (ES) and end-diastolic (ED) frames, defining the ES-ED motion vectors. The nonlinear image warping algorithm (thin-plate-spline) was then applied to warp end-systolic frame was onto the end-diastolic frames using the corresponding ES-ED motion vectors. The remaining 6 intermediate frames were also transformed to the ED coordinates using fractions of the motion vectors. Such warped images were then summed to provide the LV perfusion image in the ED phase but with counts from the full cycle. Results: The identification of the ED/ES corresponding points was successful in all cases. The corrected displacement between ED and ES images was up to 25 mm. The summed images had the appearance of the ED frames but have been much less noisy since all the counts have been used. The spatial resolution of such images appeared higher than that of summed gated images, especially in the female scans. These 'motion frozen' images could be displayed and quantified as regular non-gated tomograms including polar map paradigm. Conclusions: This image processing technique may improve the effective image resolution of summed gated myocardial perfusion images used for

  13. End-expiration respiratory gating for a high-resolution stationary cardiac SPECT system

    International Nuclear Information System (INIS)

    Chan, Chung; Sinusas, Albert J; Liu, Chi; Harris, Mark; Le, Max; Biondi, James; Grobshtein, Yariv; Liu, Yi-Hwa

    2014-01-01

    Respiratory and cardiac motions can degrade myocardial perfusion SPECT (MPS) image quality and reduce defect detection and quantitative accuracy. In this study, we developed a dual respiratory and cardiac gating system for a high-resolution fully stationary cardiac SPECT scanner in order to improve the image quality and defect detection. Respiratory motion was monitored using a compressive sensor pillow connected to a dual respiratory–cardiac gating box, which sends cardiac triggers only during end-expiration phases to the single cardiac trigger input on the SPECT scanners. The listmode data were rebinned retrospectively into end-expiration frames for respiratory motion reduction or eight cardiac gates only during end-expiration phases to compensate for both respiratory and cardiac motions. The proposed method was first validated on a motion phantom in the presence and absence of multiple perfusion defects, and then applied on 11 patient studies with and without perfusion defects. In the normal phantom studies, the end-expiration gated SPECT (EXG-SPECT) reduced respiratory motion blur and increased myocardium to blood pool contrast by 51.2% as compared to the ungated images. The proposed method also yielded an average of 11.2% increase in myocardium to defect contrast as compared to the ungated images in the phantom studies with perfusion defects. In the patient studies, EXG-SPECT significantly improved the myocardium to blood pool contrast (p < 0.005) by 24% on average as compared to the ungated images, and led to improved perfusion uniformity across segments on polar maps for normal patients. For a patient with defect, EXG-SPECT improved the defect contrast and definition. The dual respiratory–cardiac gating further reduced the blurring effect, increased the myocardium to blood pool contrast significantly by 36% (p < 0.05) compared to EXG-SPECT, and further improved defect characteristics and visualization of fine structures at the expense of increased

  14. Assessment of poststress left ventricular ejection fraction by gated SPECT: comparison with equilibrium radionuclide angiocardiography

    International Nuclear Information System (INIS)

    Acampa, Wanda; Liuzzi, Raffaele; De Luca, Serena; Capasso, Enza; Luongo, Luca; Cuocolo, Alberto; Caprio, Maria Grazia; Nicolai, Emanuele; Petretta, Mario

    2010-01-01

    We compared left ventricular (LV) ejection fraction obtained by gated SPECT with that obtained by equilibrium radionuclide angiocardiography in a large cohort of patients. Within 1 week, 514 subjects with suspected or known coronary artery disease underwent same-day stress-rest 99m Tc-sestamibi gated SPECT and radionuclide angiocardiography. For both studies, data were acquired 30 min after completion of exercise and after 3 h rest. In the overall study population, a good correlation between ejection fraction measured by gated SPECT and by radionuclide angiocardiography was observed at rest (r=0.82, p<0.0001) and after stress (r=0.83, p<0.0001). In Bland-Altman analysis, the mean differences in ejection fraction (radionuclide angiocardiography minus gated SPECT) were -0.6% at rest and 1.7% after stress. In subjects with normal perfusion (n=362), a good correlation between ejection fraction measured by gated SPECT and by radionuclide angiocardiography was observed at rest (r=0.72, p<0.0001) and after stress (r=0.70, p<0.0001) and the mean differences in ejection fraction were -0.9% at rest and 1.4% after stress. Also in patients with abnormal perfusion (n=152), a good correlation between the two techniques was observed both at rest (r=0.89, p<0.0001) and after stress (r=0.90, p<0.0001) and the mean differences in ejection fraction were 0.1% at rest and 2.5% after stress. In a large study population, a good agreement was observed in the evaluation of LV ejection fraction between gated SPECT and radionuclide angiocardiography. However, in patients with perfusion abnormalities, a slight underestimation in poststress LV ejection fraction was observed using gated SPECT as compared to equilibrium radionuclide angiocardiography. (orig.)

  15. Left ventricular ejection fraction determined by gated Tl-201 perfusion SPECT and quantitative software

    International Nuclear Information System (INIS)

    Hyun, In Young; Kim, Sung Eun; Seo, Jeong Kee; Hong, Eui Soo; Kwan, Jun; Park, Keum Soo; Lee, Woo Hyung

    2000-01-01

    We compared estimates of ejection fraction (EF) determined by gated Tl-201 perfusion SPECT (g-Tl-SPECT) with those by gated blood pool (GBP) scan. Eighteen subjects underwent g-Tl-SPECT and GBP scan. After reconstruction of g-Tl-SPECT, we measured EF with Cedars software. The comparison of the EF with g-Tl-SPECT and GBP scan was assessed by correlation analysis and Bland Altman plot. The estimates of EF were significantly different (p<0.05) with g-Tl-SPECT (40%±14%) and GBP scan (43%±14%). There was an excellent correlation of EF between g-Tl-SPECT and GBP scan (r=3D0.94, p<0.001). The mean difference of EF between GBP scan and g-Tl-SPECT was +3.2%. Ninety-five percent limits of agreement were ±9.8%. EF between g-Tl-SPECT and GBP scan were in poor agreement. The estimates of EF by g-Tl-SPECT was well correlated with those by GBP scan. However, EF of g-Tl-SPECT doesn't agree with EF of GBP scan. EF of g-Tl-SPECT can't be used interchangeably with EF of GBP scan.=20

  16. Assessment of sistemic ventricle function in corrected transposition of great arteries with Gated SPECT: comparison with radionuclide ventriculography

    International Nuclear Information System (INIS)

    Alexanderson, E.; Espinola, N.; Duenas, D.; Fermon, S.; Acevedo, C.; Martinez, C.

    2002-01-01

    Corrected trasposition of great arteries is a uncommon congenital heart disease where the right ventricle works as the sistemic one. QGS Gated SPECT program was designed to recognize the contours of left ventricle being a good method to evaluate left ventricle ejection fraction. The purpose of this study was to evaluate the right ventricle ejection fraction (RVEF) by gated SPECT using Tc-99mSestaMIBI in comparison with radionuclide ventriculography (RVG) in patients with corrected trasposition of great arteries. Methods: We performed gated SPECT and radionuclide ventriculography within 15 days of each other in 7 adults consecutive patients with the diagnosis of corrected trasposition of great arteries (5 men, 2 women; mean age 47 y). Gated tomographic data, including ventricular volumes and ejection fraction, were processed using QGS automatic algorithm, whereas equilibrium radionuclide ventriculography used standard techniques. Results: We found a good correlation between right ventricle ejection fraction obtained with Gated SPECT compared with equilibrium radionuclide ventriculography. The mean of the RVEF with Gated SPECT was 41.2% compared with 44.2% of RVEF with equilibrium radionuclide ventriculography. Both methods recognized abnormal RVEF in 5 patients ( 50%) with Gated SPECT and abnormal with RVG meanwhile another patient had normal RVEF with RVG and abnormal with Gated SPECT. Conclusion: Quantitative gated tomography, using Tc 99mSestaMIBI, has a good correlation with radionuclide ventriculography for the assessment of right ventricle ejection fraction in patients with corrected trasposition of great arteries. These results support the clinical use of this technique among these patients

  17. Diagnosis of severe and extensive coronary artery disease using gated myocardial perfusion SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Ihn Ho; Lee, Hyoung Woo; Won, Kyu Chang; Park, Jong Sun; Sin, Dog Gu; Kim, Young Jo; Shim, Bong Sub [College of Medicine, Yeungnam Univ., Taegu (Korea, Republic of)

    1999-07-01

    Left ventricular volumes and ejection fractions constitute important informations in the diagnosis and prognosis of cardiac disease. Aim of the study is to verify if the assessment of left ventricular function and perfusion together by gated myocardial perfusion SPECT is useful for diagnosing severe and extensive CAD. We examined 27 consecutive patients (17 males and 10 females, mean age : 60.1 years) who underwent two day rest/stress Tc-99m MIBI gated SPECT. Stress was done with adenosine. Post-stress gated SPECT was done at 1 hour after an injection of Tc-99m MIBI (740 MBq). All patients underwent coronary angiography after gated SPECT within 1 month. We divided them three groups with single vessel disease, double vessel disease and triple vessel disease or severe proximal left coronary artery stenosis. Extent of Defect (ED), Reversibility of Extent (RE), Severity of Defect (SD) and Severity of Reversibility (SR) were calculated by CEqual program. Post-stress LVEF, Rest LVEF, End-diastolic volume(EDV), End-systolic volume(ESV), Transient Ischemic Dilation (TID) of left ventricle (Post-stress EDV/Rest EDV) were calculated using gated SPECT quantification program. Left ventricle is divided with 18 segments and wall motion was scored (normal=0, mild hypokinesia =1, severe hypokinesia =2, akinesia =3 and dyskinesia =4), and then post-stress summed wall motion score was calculated. Post-stress summed wall motion score and post-stress LVEF were significant differences between three groups ( P <0.01). Extent of defect, Extent of reversibility, Severity of defect and severity of reversibility in Polar map were significant differences between three groups ( P <0.01). Post-stress Transient left ventricular dilatation and test LVEF were not significant differences between three groups ( P > 0.05). The gated SPECT pattern (low post-stress LVEF and post-stress summed wall motion score) add important diagnostic information over ungated perfusion data (high ED, ER and SR and

  18. The usefulness of treatment evaluation of severe heart failure by ECG-gated myocardial SPECT

    International Nuclear Information System (INIS)

    Ohkoshi, Nobuyuki; Watanabe, Shingo; Matsumoto, Tooru

    2011-01-01

    Our purpose of study was to investigate the usefulness of treatment evaluation of severe heart failure by Electrocardiogram (ECG)-gated myocardial single photon emission computed tomography (SPECT). We evaluated the cardiac function in the case of severe heart failure by gated SPECT and compared it with the cardiac function obtained by left ventriculography (LVG), echocardiography, cardiac MRI, and B-type natriuretic peptide (BNP) values. We investigated the correlation of ejection fraction (EF), time lag of wall motion between the septal and lateral walls of the left ventricle for cardiac resynchronization therapy (CRT) and wall thickening (WT). We classified the left ventricular (LV) into basal, middle and apical areas for comparison of WT. We investigated the effect of a perfusion defect score in these comparisons. The gated SPECT results were correlated with comparative subjects in EF. The results were correlated with MRI on the middle area of the LV in the comparison of WT. We thought it was possible that there was an effect from a perfusion defect score in a time lag comparison of wall motion. Treatment evaluation of severe heart failure by gated SPECT is useful, because it is able to obtain three-dimensional cardiac function analysis, and it offers objectivity and reproducible quantitative evaluation. At the same time, perfusion SPECT is helpful for CRT and LV-plasty. (author)

  19. The additive prognostic value of perfusion and functional data assessed by quantitative gated SPECT in women

    NARCIS (Netherlands)

    Y.G.C.J. America (Yves); J.J. Bax (Jeroen); H. Boersma (Eric); M. Stokkel (Marcel); E.E. van der Wall (Ernst)

    2009-01-01

    textabstractBackground: The aim of this study was to assess the prognostic value of technetium-99m tetrofosmin gated SPECT imaging in women using quantitative gated single photon emission computed tomography (SPECT) imaging. Methods: We followed 453 consecutive female patients. Average follow-up was

  20. Gated spect myocardial perfusion scintigraphy for identifying septal perfusion artifacts in left bundle branch block

    International Nuclear Information System (INIS)

    Afzal, M.S.; Imran, M.B.; Akhtar, M.S.; Muhammand, K.; Nadeem, A.; Aslam, N.; Khurshid, S.J.; Farooq, U.I.; Sohaib, M.

    2006-01-01

    To determine the role of gated Single Photon Emission Computed Tomography (SPECT) for accurate assessment of myocardial perfusion scintigraphy (MPS) of patients with left bundle branch block (LBBB). MPS data of patients with LBBB was analyzed. Resting gated SPECT MPS was performed after an injection of 740 MBq 99mTc-MIBI in 10 normal and 25 subjects with LBBB (with low probability of coronary artery disease). Visual and quantitative analyses were done on non-gated (NG), end diastolic (ED), end systolic (ES) images. Calculations included septal to lateral wall ratio (SLR), myocardial thickening (MT=% increase in counts during systole) at end systolic phase and myocardial thickening at peak level (% peak MT). Septal hypoperfusion was noted in 19 (76%) patients on NG images and in only 1 (4%) patient on gated SPECT ED images. On NG images of LBBB group, SLR was lower than in controls (0.68 +- 0.07 vs. 0.87 +- 0.05, p<0.001). SLR of LBBB patients approached to that of control group in gated SPECT ED data (0.86 +- 0.06 vs 0.88 +- 0.06, p=ns). Myocardial thickening at ES for septum was markedly lower in LBBB group than in controls (21.83% +- 10.86 vs. 66.32% +- 20.15, p<0.001). (author)

  1. Functional assessment of the right ventricle with gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Wadhwa, S.S.; Abbati, D.; Carolan, M.

    2002-01-01

    Full text: Evaluation of right ventricular function can provide valuable information in a variety of cardiac and non-cardiac conditions. Functional assessment of the right ventricle is difficult owing to its anatomy and geometry. We describe a method of assessing right ventricular function using gated myocardial perfusion SPECT. In 20 patients right and left ventricular ejection fractions (RVEF, LVEF) were determined using gated blood pool (GBPS) and gated myocardial perfusion SPECT (GSPECT). To avoid contamination with right atrial activity the two frame method was adopted for gated blood pool data when measuring RVEF. In 9 patients with normal right ventricles, an index of wall thickening for the right ventricle was derived from the peak systolic and diastolic counts in the free wall. There was good linear correlation between the two methods adopted for calculation of LVEF and RVEF. Bland - Airman analysis demonstrated good agreement between the two methods with no specific bias. The mean LVEF was 47.9 +/-12% (GBPS) and 47.3 +/- 12.4 (GSPECT). The mean RVEF was 43.2 +/- 9.6% (GBPS) and 44.2 +/- 8.5% (GSPECT). In both cases the values were significantly different. The mean wall motion index was 35%. There was no correlation between the wall thickness index and ejection fraction however the index was greater in patients with normal right ventricle than in those with reduced RVER Gated SPECT offers an alternative to GBPS for the functional assessment of the right ventricle. Utilising GSPECT will allow the simultaneous assessment of both the right and left ventricles. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  2. Evaluation of left ventricular function and volume in patients with dilated cardiomyopathy: Gated myocardial single-photon emission tomography (SPECT) versus echocardiography

    International Nuclear Information System (INIS)

    Berk, Fatma; Isgoren, S.; Demir, H.; Kozdag, G.; Ural, D.; Komsuoglu, B.

    2005-01-01

    Left ventricular function, volumes and regional wall motion provide valuable diagnostic information and are of long-term prognostic importance in patients with dilated cardiomyopathy (DCM). This study was designed to compare the effectiveness of 2D-echocardiography and gated single-photon emission tomography (SPECT) for evaluation of these parameters in patients with DCM. Gated SPECT and 2D-echocardiography were performed in 33 patients having DCM. Gated SPECT data, including left ventricular ejection fraction (LVEF), were processed using an automated algorithm. Standard technique was used for 2D-echocardiography. Regional wall motion was evaluated using both modalities and was scored by two independent observers using a 16-sement model with a 5-point scoring system. The overall agreement between the two imaging modalities for the assessment of regional wall motion was 56% (298/528 segments). With gated SPECT, LEVF, end-diastolic volume (EDV), and end-diastolic volume (EDV), and end-systolic volume (ESV) were 27+-9%, 217+-73mL, respectively, and 30.8%, 195+-58mL and, 137+-48 mL with echocardiography. The correlation between gated SPECT and 2-D-echocardiography was good (r=0.76, P<0.01) for the assessment of LVEF. The correlation for EDV and ESV were also good, but with wider limits of agreement (r=0.72, P<0.01 and r=0.73, P<0.01, respectively) and significantly higher values were obtained with gated SPECT (P<0.01). Gated SPECT and 2D-echocardiography correlate well for the assessment of LV function and LV volumes. Like 2D-echocardiography, gated SPECT provides reliable information about LV function and dimension with the additional advantage of perfusion data. (author)

  3. Experiencias sorprendentes de química con indicadores de pH caseros

    Directory of Open Access Journals (Sweden)

    Heredia Avalos, S.

    2006-01-01

    Full Text Available En este trabajo se describen varias experiencias sencillas relacionadas con las reacciones ácido-base. Todas ellas pueden realizarse con utensilios de cocina y usando sustancias baratas que pueden encontrarse fácilmente en un supermercado, una farmacia o en casa. En concreto, se describe la forma de obtener algunos indicadores de pH a partir de extractos vegetales o de medicamentos. Además, se proponen varias experiencias en las que se hace uso de estos indicadores con el fin de estudiar las reacciones ácido-base. Todas estas experiencias están enfocadas a alumnos de enseñanza secundaria.

  4. Evaluation and reduction of respiratory motion artifacts in small animal SPECT with GATE

    International Nuclear Information System (INIS)

    Lee, C.-L.; Park, S.-J.; Kim, H.-J.

    2015-01-01

    The degradation of image quality caused by respiration is a major impediment to accurate lesion detection in single photon emission computed tomography (SPECT) imaging. This study was performed to evaluate the effects of lung motion on image quantification. A small animal SPECT system with NaI(Tl) was modeled in the Geant4 application for tomographic emission (GATE) simulation for a lung lesion using a 4D mouse whole-body phantom. SPECT images were obtained using 120 projection views acquired from 0 o to 360 o with a 3 o step. Slices were reconstructed using ordered subsets expectation maximization (OS-EM) without attenuation correction with five iterations and four subsets. Image quality was compared between the static mode without respiratory motion, and dynamic mode with respiratory motion in terms of spatial resolution was measured by the full width at half maximum (FWHM), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). The FWHM of the non-gated image and the respiratory gated image were also compared. Spatial resolution improved as activity increased and lesion diameter decreased in the static and dynamic modes. The SNR and CNR increased significantly as lesion activity increased and lesion diameter decreased. Our results show that respiratory motion leads to reduced contrast and quantitative accuracy and that image quantification depends on both the amplitude and the pattern of the respiratory motion. We verified that respiratory motion can have a major effect on the accuracy of measurement of lung lesions and that respiratory gating can reduce activity smearing on SPECT images

  5. Evaluation of left ventricular ejection fraction using quantitative gated SPECT (QGS)

    International Nuclear Information System (INIS)

    Musa, M. A. A.

    2010-07-01

    Electrocardiographic ally gated myocardial perfusion SPECT (G SPECT) is a state-of the art technique for the combined evaluation of myocardial perfusion and left ventricular function within a single study. It is currently one of the most commonly performed cardiology procedures in a nuclear medicine department. Automation of the image processing and quantification has made this techniques highly reproducible, practical and user friendly in the clinical setting . In patients with coronary artery disease, gating enhances the diagnostic and prognostic capability of myocardial perfusion imaging provides incremental information over the the perfusion data, and has shown potentials for myocardial viability assessment and sequential follow-up after therapy. Evaluation of the left ventricular (L V) function is important in clinical cardiology. Quantifying the degree and extent of the L V functional abnormalities permits a systematic assessment of the disease process on the myocardial performance. The aim of this thesis is to evaluate left ventricular ejection fraction (LVEF) in patients with no evidence of ischemic response during the stress test. This investigation was carried out in view of the few reports concerning the findings ventricular function with gated SPECT in these situations in the normal population, which is relevant when considering the possibility of myocardial stunning. Method: We prospectively studied 30 selected patients, in difference age and gender. A one-day protocol was used, with injection 555 MBq - 1.11 MBq (15 - 30 mCi) of 99 mTc-M1 B1 at stress and rest. Gated perfusion SPECT was acquired 30 to 60 minutes after radiotracer injection in both condition and processed using QGSPECT software. Difference between stress and rest LVEF was calculated. Result and conclusion: rest LVEF was higher in the stress (exercise) group, A trend line was done in both groups and r-value was (0.9) and p=0.04 in acceptance value. Standard deviation of LVEF also was

  6. Agreement of left ventricular ejection fraction and volumes between adenosine stress TL-201 gated SPECT and echocardiography

    Energy Technology Data Exchange (ETDEWEB)

    Pai, M. S. [College of Medicine, Univ. of Ewha, Seoul (Korea, Republic of); Moon, D. H.; Kim, H. M.; Yang, Y. J.; Kang, D. H. [Asan Medical Center, Seoul (Korea, Republic of)

    2003-07-01

    Electrocardiogram-gated TI-201 SPECT measurements of left ventricular ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volume (ESV) have shown high correlation with conventional methods. However, how much these parameters measured by TI-201 gated SPECT differ from those by echocardiography has not been assessed. Adenosine stress (Ad-G) and redistribution TI-201 gated SPECT (Re-G) and resting echocardiography were conducted in 337 patients (184 male, 153 female). EDV, ESV and LVEF measured by QGS software were compared with the results by echocardiography. Patients with arrhythmia (atrial fibrillation or frequent premature contractions) or evidence of fixed or reversible perfusion defects on TI-201 SPECT were excluded. EF, EDV and ESV measured by Ad-G (63.3{+-}9.8,73.8{+-}30.2,29.1{+-}20.1) and Re-G (65.2{+-}11.6,69.1{+-}30.1,26.5{+-}20.3) correlated well with those by Echo (61.4{+-}7.9,78.3{+-}2.7, 30.7{+-} 17.5 ; r of Ad-G=0.547, 0.850, 0.827, p<0.001 ; r of Re-G=0.585, 0.838, 0.819, p<0.001). However the difference (mean, SD, SEE of Echo - gated SPECT) was statistically significant (EF: Ad-G=1.71, 8.92, 0.48, Re-G=3.59, 10.39, 0.56, p<0.001 ; EDV: Ad-G=4.75, 16.21, 0.88, Re-G=9.53, 16.77, 0.91, p<0.001 ; ESV: Ad-G=1.75, 11.35, 0.61, p<0.05, Re-G=4.29, 11.7, 0.63, p<0.001). Bland-Altman plots showed that the difference of EDV and ESV did not vary in any systematic way over the range of measurement, whereas the difference of EF increased with increasing average EF by Echo and gated-SPECT. The difference of EF, EDV, and ESV between Ad-G and Echo was significantly smaller than those between Re-G and Echo (p<0.001). Gated TI-201 SPECT underestimates EDV and ESV over a wide range of volume. As a result, EF by gated TI-201 SPECT is overestimated especially in patients with small LV volume. Ad-G is preferable to Re-G in assessing left ventricular ejection fraction and volume in place of Echo because of smaller bias.

  7. Comparison of automatic quantification software for the measurement of ventricular volume and ejection fraction in gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Van Staden, J.A.; Herbst, C.P.; Du Raan, H.; Lotter, M.G.; Otto, A.C.

    2004-01-01

    Full text: Introduction: Gated myocardial perfusion SPECT has been used to calculate left ventricular ejection fraction (LVEF) and left ventricular end-diastolic volume (LVEDV) and has correlated well with conventional methods. However, the comparative accuracy of and correlations across various types of gated SPECT software are not well understood. Materials and methods: Twelve patients participated in a radionuclide gated blood-pool (GBP) study in addition to undergoing 99m Tc-sestamibi gated SPECT. Three different software algorithms, Quantitative Gated SPECT (QGS) from Cedars-Sinai, MultiDim from Stanford University Medical School and GQUANT from Alfa Nuclear were used to compute LVEF and LVEDV. These software algorithms operate in 3-dimensional space, two dependent on surface detection and the other on statistical parameters. The LVEF as calculated from gated SPECT myocardial perfusion images were compared with LVEF calculated from the GBP studies in the same patients to assess accuracy of the three software algorithms. Results: The software success-rate was 92% (11/12 pts) for MultiDim and 100% for the QGS and GQUANT. Agreement between LVEF measured with MultiDim and QGS, MultiDim and GQUANT and QGS and GQUANT were excellent (LVEF-MuItidim 0.80 LVEF QGS +5.02, r = 0.93, LVEF GQUANT = 1.10 LVEF MuItidim -1.33, r 0.90 and LVEF GQUANT = 1.02 LVEF QGS -1.40, r = 0.96). The correlation coefficient for LVEF between gated SPECT and the GBP study was 0.95, 0.95 and 0.97, for MultiDim, GQUANT and QGS, respectively. Conclusion: All 3 software programs showed good correlation between LVEF for gated SPECT and the GBP study. Good agreement for LVEF was observed also between the three software algorithms. However, because each method has unique characteristics that depend on its specific algorithm and thus behaves differently in the various patients, the methods should not be used interchangeably. (author)

  8. Reproducibility of the assessment of myocardial function using gated Tc-99m-MIBI SPECT and quantitative software

    International Nuclear Information System (INIS)

    Lee, Dong Soo; Cheon, Gi Jeong; Ahn, Ji Young; Jeong, Joon Ki; Lee, Myung Chul

    1998-01-01

    We investigated reproducibility of the quantification of left ventricular volume and ejection fraction, and grading of myocardial wall motion and systolic thickening when we used gated myocardial SPECT and Cedars quantification software. We performed gated myocardial SPECT in 33 consecutive patients twice in the same position after Tc-99m-MIBI SPECT. We used 16 frames per cycle for the gating of sequential Tc-99m-MIBI SPECT. After reconstruction, we used Cedars quantitative gated SPECT and calculated ventricular volume and ejection fraction (EF). Wall motion was graded using 5 point score. Wall thickening was graded using 4 point score. Coefficient of variation for re-examination of volume and fraction were calculated. Kappa values (k-value) for assessing reproducibility of wall motion or wall thickening were calculated. Enddiastolic volumes (EDV) ranged from 58 ml to 248 ml (122 ml +/-42 ml), endsystolic volumes (ESV) from 20 ml to 174 ml (65 ml+/-39 ml), and EF from 20% to 68% (51%+/-14%). Geometric mean of standard deviations of 33 patients was 5.0 ml for EDV, 3.9 ml for ESV and 1.9% for EF. Their average differences were not different from zero (p>0.05). k-value for wall motion using 2 consecutive images was 0.76 (confidence interval: 0.71-0.81). k-value was 0.87 (confidence interval: 0.83-0.90) for assessment of wall thickening. We concluded that quantification of functional indices, assessment of wall motion and wall thickening using gated Tc-99m MIBI SPECT was reproducible and we could use this method for the evaluation of short-acting drug effect

  9. Quantification of left ventricular function by gated myocardial perfusion SPECT using multidimTM

    International Nuclear Information System (INIS)

    Huang Jin; Song Wenzhong; Chen Mingxi

    2004-01-01

    Objective: To evaluate the accuracy of left ventricular function by gated SPECT using the software Multidim TM . Methods: Rest gated SPECT was performed on 42 cases involved 26 normal subjects and 16 patients with myocardial infarct (MI). All cases underwent rest equilibrium radionuclide angiocardiography (ERNA) within 1 w. Results: (1)End diastolic volume (EDV), end systolic volume (ESV) and left ventricular ejection fraction(LVEF)were calculated using the software MultidimtMand ERNA. The correlation coefficient between the two Methods was 0.90,0.89,0.92 respectively(P TM , but the EDV and ESV value measured by this software maybe high with small heart. (authors)

  10. LV dyssynchrony as assessed by phase analysis of gated SPECT myocardial perfusion imaging in patients with Wolff-Parkinson-White syndrome

    International Nuclear Information System (INIS)

    Chen, Chun; Li, Dianfu; Miao, Changqing; Zhou, Yanli; Cao, Kejiang; Feng, Jianlin; Lloyd, Michael S.; Chen, Ji

    2012-01-01

    The purpose of this study was to evaluate left ventricular (LV) mechanical dyssynchrony in patients with Wolff-Parkinson-White (WPW) syndrome pre- and post-radiofrequency catheter ablation (RFA) using phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days post-RFA. Electrophysiological study (EPS) was used to locate accessory pathways (APs) and categorize the patients according to the AP locations (septal, left and right free wall). Electrocardiography (ECG) was performed pre- and post-RFA to confirm successful elimination of the APs. Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA. Among the 45 patients, 3 had gating errors, and thus 42 had SPECT phase analysis. Twenty-two patients (52.4 %) had baseline LV dyssynchrony. Baseline LV dyssynchrony was more prominent in the patients with septal APs than in the patients with left or right APs (p < 0.05). RFA improved LV synchrony in the entire cohort and in the patients with septal APs (p < 0.01). Phase analysis of gated SPECT MPI demonstrated that LV mechanical dyssynchrony can be present in patients with WPW syndrome. Septal APs result in the greatest degree of LV mechanical dyssynchrony and afford the most benefit after RFA. This study supports further investigation in the relationship between electrical and mechanical activation using EPS and phase analysis of gated SPECT MPI. (orig.)

  11. LV dyssynchrony as assessed by phase analysis of gated SPECT myocardial perfusion imaging in patients with Wolff-Parkinson-White syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chun; Li, Dianfu; Miao, Changqing; Zhou, Yanli; Cao, Kejiang [First Affiliated Hospital of Nanjing Medical University, Department of Cardiology, Nanjing, Jiangsu (China); Feng, Jianlin [First Affiliated Hospital of Nanjing Medical University, Department of Nuclear Medicine, Nanjing, Jiangsu (China); Lloyd, Michael S. [Emory University School of Medicine, Division of Cardiology, Atlanta, GA (United States); Chen, Ji [Emory University School of Medicine, Department of Radiology and Imaging Sciences, Atlanta, GA (United States)

    2012-07-15

    The purpose of this study was to evaluate left ventricular (LV) mechanical dyssynchrony in patients with Wolff-Parkinson-White (WPW) syndrome pre- and post-radiofrequency catheter ablation (RFA) using phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days post-RFA. Electrophysiological study (EPS) was used to locate accessory pathways (APs) and categorize the patients according to the AP locations (septal, left and right free wall). Electrocardiography (ECG) was performed pre- and post-RFA to confirm successful elimination of the APs. Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA. Among the 45 patients, 3 had gating errors, and thus 42 had SPECT phase analysis. Twenty-two patients (52.4 %) had baseline LV dyssynchrony. Baseline LV dyssynchrony was more prominent in the patients with septal APs than in the patients with left or right APs (p < 0.05). RFA improved LV synchrony in the entire cohort and in the patients with septal APs (p < 0.01). Phase analysis of gated SPECT MPI demonstrated that LV mechanical dyssynchrony can be present in patients with WPW syndrome. Septal APs result in the greatest degree of LV mechanical dyssynchrony and afford the most benefit after RFA. This study supports further investigation in the relationship between electrical and mechanical activation using EPS and phase analysis of gated SPECT MPI. (orig.)

  12. EXPERIENCIAS PEDAGÓGICAS CON EL PÁRRAFO

    Directory of Open Access Journals (Sweden)

    Ligni Molano Barona

    2010-01-01

    Full Text Available En este documento se compendia la experiencia que tres profesoras de lengua materna han construido a lo largo de su actividad docente, en lo relacionado con el párrafo. Está estructurado en tres puntos. En el primero, ¿Qué es un párrafo?, se abordan elementos de orden teórico, que, a modo de referentes, sustentan la búsqueda de un concepto propio y eficaz a la hora de emprender la escritura con los estudiantes. Con este fin, se realizó un pequeño estado del arte sobre el estudio del párrafo, en el que se escogieron cinco autores, cuya experiencia en la didáctica textual es bastante amplia, y se indagaron a los pares de la Universidad Icesi. En el segundo, ¿Para qué sirve un párrafo?, se reflexiona acerca de la utilidad y la importancia del párrafo en la escritura de cualquier tipo de texto. En el tercero, ¿Cómo se puede enseñar a escribirlo?, se plantea una metodología para el trabajo del párrafo en el aula.

  13. Pharmacologic stress-induced stunning: evaluation with quantitative gated SPECT

    International Nuclear Information System (INIS)

    Chun, K. A.; Cho, I. H.; Won, K. J.; Lee, H. W.

    2000-01-01

    The after-effect of pharmacologic stress (adenosine) on left ventricular (LV) function, end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (LVEF) were evaluated after pharmacologic stress with Tl-201 and 99m Tc-MIBI SPECT using an automated program in 153 subjects. The subjects were grouped as follows: 1) Tl-201 group (n=35, male 18, female 17, mean age: 58 years); normal scan (n=24), ischemia (n=8) and infarction (n=3). 2) 99m Tc-MIBI group (n=118, male 60, female 58, mean age: 62 years); normal scan (n=73), ischemia (n=20) and infarction (n=25) based on the interpretation of perfusion images. All patients were in sinus rhythm during the study. 1)Tl-201 group; In patients with ischemia (the mean time interval between injection and acquisition is 12.3 min), post-stress LVEF was significantly depressed after adenosine infusion (51.2 ± 6.3% vs 59.8± 8.2%, p 99m Tc-MIBI group; In patients with ischemia (the mean time interval between injection and acquisition is 80 min), post-stress LVEF was significantly depressed after adenosine infusion (p<0.001) and ΔLVEF was 5.1%. Eight patients (40%) showed an increase in LVEF greater than 5% from poststress to rest. Poststress ESV (37.1±17.3 ml) was significantly higher than ESV (31.3±15.5 ml, p<0.001) at rest, but no significant difference in EDV. These results showed that pharmacologic stress induced stunning is well noted in the early quantitative gated SPECT in ischemic patients and also observed in the delayed gated SPECT, even though the rate of stunning is less than the early SPECT

  14. Normal value of functional parameters in gated myocardial perfusion SPECT in patients with low risk of coronary artery disease: emory cardiac tool box program

    Energy Technology Data Exchange (ETDEWEB)

    Kang, D. Y.; Kim, M. H.; Kim, Y. D.; Kim, D. K. [Donga University College of Medicine, Busan (Korea, Republic of)

    2002-07-01

    Absolute value of the functional data of gated myocardial perfusion SPECT is necessary to determine that individual patient is normal or not. Tc-99m MIBI gated myocardial perfusion SPECT was performed using emory cardiac tool box program. All patients (M:F=15:36, age 64{+-}10 yrs) showed normal myocardial perfusion. The patients with following characteristics were excluded; previous angina or MI, ECG change with Q wave or ST-T change, diabetes mellitus, hypercholesterolemia, typical chest pain and hypertension. In all patients, myocardial mass is 117{+-}23 g in stress gated SPECT, 106{+-}22 g in stress ungated SPECT and 102{+-}21 g in rest ungated SPECT. EDV is 90{+-}28 ml, ESV 26{+-}20 ml, SV 66{+-}21 ml, EF 73{+-}10 % and TID 1.06{+-}0.14. Myocardial mass in rest ungated SPECT is significantly different between men and women (p=0.025). Myocardial mass is significantly different between stress gated SPECT and stress ungated SPECT (p=0.000), and between stress ungated SPECT and rest ungated SPECT (p=0.003). We provide normal value of functional parameters to determine the abnormality of individual patients in patients with low risk of coronary artery disease.

  15. LV dyssynchrony as assessed by phase analysis of gated SPECT myocardial perfusion imaging in patients with Wolff-Parkinson-White syndrome.

    Science.gov (United States)

    Chen, Chun; Li, Dianfu; Miao, Changqing; Feng, Jianlin; Zhou, Yanli; Cao, Kejiang; Lloyd, Michael S; Chen, Ji

    2012-07-01

    The purpose of this study was to evaluate left ventricular (LV) mechanical dyssynchrony in patients with Wolff-Parkinson-White (WPW) syndrome pre- and post-radiofrequency catheter ablation (RFA) using phase analysis of gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Forty-five WPW patients were enrolled and had gated SPECT MPI pre- and 2-3 days post-RFA. Electrophysiological study (EPS) was used to locate accessory pathways (APs) and categorize the patients according to the AP locations (septal, left and right free wall). Electrocardiography (ECG) was performed pre- and post-RFA to confirm successful elimination of the APs. Phase analysis of gated SPECT MPI was used to assess LV dyssynchrony pre- and post-RFA. Among the 45 patients, 3 had gating errors, and thus 42 had SPECT phase analysis. Twenty-two patients (52.4%) had baseline LV dyssynchrony. Baseline LV dyssynchrony was more prominent in the patients with septal APs than in the patients with left or right APs (p syndrome. Septal APs result in the greatest degree of LV mechanical dyssynchrony and afford the most benefit after RFA. This study supports further investigation in the relationship between electrical and mechanical activation using EPS and phase analysis of gated SPECT MPI.

  16. Global and regional left ventricular function: a comparison between gated SPECT, 2D echocardiography and multi-slice computed tomography

    International Nuclear Information System (INIS)

    Henneman, Maureen M.; Bax, Jeroen J.; Holman, Eduard R.; Schuijf, Joanne D.; Jukema, J.W.; Wall, Ernst E. van der; Stokkel, Marcel P.M.; Lamb, Hildo J.; Roos, Albert de

    2006-01-01

    Global and regional left ventricular (LV) function are important indicators of the cardiac status in patients with coronary artery disease (CAD). Therapy and prognosis are to a large extent dependent on LV function. Multi-slice computed tomography (MSCT) has already earned its place as an imaging modality for non-invasive assessment of the coronary arteries, but since retrospective gating to the patient's ECG is performed, information on LV function can be derived. In 49 patients with known or suspected CAD, coronary angiography with MSCT imaging was performed, in addition to gated SPECT and 2D echocardiography. LV end-diastolic and LV end-systolic volumes and LV ejection fraction were analysed with dedicated software (CMR Analytical Software System, Medis, Leiden, The Netherlands for MSCT; gated SPECT by QGS, Cedars-Sinai Medical Center, Los Angeles, CA, USA), and by the biplane Simpson's rule for 2D echocardiography. Regional wall motion was evaluated according to a 17-segment model and a three-point score system. Correlations were fairly good between gated SPECT and MSCT (LVEDV: r=0.65; LVESV: r=0.63; LVEF: r=0.60), and excellent between 2D echocardiography and MSCT (LVEDV: r=0.92; LVESV: r=0.93; LVEF: r=0.80). Agreement for regional wall motion was 95% (κ=0.66) between gated SPECT and MSCT, and 96% (κ=0.73) between 2D echocardiography and MSCT. Global and regional LV function and LV volumes can be adequately assessed with MSCT. Correlations with 2D echocardiography are stronger than with gated SPECT. (orig.)

  17. Experiencias y aprendizajes con juegos cooperativos

    Directory of Open Access Journals (Sweden)

    Evelyn Cerdas Agüero

    2013-03-01

    Full Text Available El presente trabajo tiene como objetivo presentar experiencias y aprendizajes que  han logrado algunos grupos de docentes con los que se ha trabajado por medio de talleres de juegos cooperativos para la paz. Los talleres se han facilitado desde la actividad de extensión Aula Activa: juegos cooperativos para la Educación para la Paz que se ha implementado en el  Instituto de Estudios Latinoamericanos (IDELA desde el 2006. En este trabajo  nos enfocamos en el trabajo con docentes del Ministerio de Educación Pública (MEP de Costa Rica, proceso que deja una serie de aprendizajes actitudinales, de valores, habilidades y cognocitivos.

  18. Reproducibility of non-invasive measurement for left ventricular contractility using gated myocardial SPECT

    International Nuclear Information System (INIS)

    Kim, Kyeon Min; Lee, Dong Soo; Kim, Yu Kyeong; Cheon, Gi Jeong; Kim, Seok Ki; Chung, June Key; Lee, Myung Chul

    2001-01-01

    We tried to establish the reproducibility of the measurement of maximal elastance (Emax) and to compare the degree of the reproducibility of two estimation methods: single pressure-volume loop method and parameter optimization method. In 47 patients (42 males and 5 females, 53 ± 10 years old) with suspected coronary artery disease (ejection fraction; 22-68%), gated Tc-99m MIBI myocardial SPECT and arterial tonometry were acquired, In 11 patients among these 47 patients, gated SPECT and tonometry were performed twice consecutively with patients in situ. Emax and void volume (Vo) were estimated using single pressure-volume loop method of Lee and parameter optimization method based on linear approximation of Yoshizawa. Correlation between the consecutive measurements by each method and correlation between the two estimation methods were compared. Reproducibility of Emax (r=0.96) and Vo (r=0.99) by single pressure-volume method was better than the reporducibility of Emax (r=0.89) and Vo (r=0.64) by parameter optimization method. Correlations of Emax and Vo were fair between the two methods. The correlation of Emax (r=0.77) was better thn that of Vo (r=0.65). Reproducibiity of Emax measurement by single pressure-volume loop method using gated myocardial SPECT and arterial tonometry was excellent. Reproducibility by parameter optimization method was also but was less than that achieved by single pressure-volume method

  19. Is 16-frame really superior to 8-frame gated SPECT for the assessment of left ventricular volumes and ejection fraction? Comparison of two simultaneously acquired gated SPECT studies

    International Nuclear Information System (INIS)

    Montelatici, Giulia; Sciagra, Roberto; Passeri, Alessandro; Dona, Manjola; Pupi, Alberto

    2008-01-01

    Conflicting data exist about the difference between 8- and 16-frame gated single-photon emission computed tomography (SPECT) left ventricular volumes and ejection fraction (EF); moreover, the influence of framing on detection of stress-induced functional changes is unknown. In 133 patients, two separate gated SPECT studies, one with 8 and one with 16 frames, were simultaneously acquired during a single gantry orbit using dedicated software. In 33 of 133 patients, two additional studies (with 8 and 16 frames, respectively) were acquired using arrhythmia rejection. Left ventricular EF and volumes were calculated using the QGS software. Stress-induced ischemia was identified on summed perfusion images. Arrhythmia-rejection did not influence volumes and EF independently of framing rate. Using data without arrhythmia-rejection, there was a significant difference in volumes and EF between 8 and 16 frames both in resting and post-stress gated SPECT. However, the difference was small: 2.6% for resting and 2.8% for post-stress EF. Both using 8 and 16 frames, there were significantly larger volumes and lower EF in patients with than without stress-induced ischemia. A stress-induced decrease >5 EF units was observed in 26 of 133 patients using 8 and in 23 of 133 using 16 frames, respectively, with finding agreement in 19 patients. Comparing two simultaneously acquired studies, the use of 16 instead of 8 frames has minor and predictable influence on functional data. Furthermore, there are no differences in the detection of stress-induced functional changes. The advantage of 16 over 8 frames in the daily clinical practice appears questionable. (orig.)

  20. Left ventricular functional parameters by gated SPECT myocardial perfusion imaging in a Latin American country.

    Science.gov (United States)

    Kapitan, Miguel; Beltran, Alvaro; Beretta, Mario; Mut, Fernando

    2018-04-01

    There is paucity of data on left ventricular (LV) functional parameters using gated SPECT myocardial perfusion imaging (MPI) from the Latin American region. This study provides detailed information in low-risk patients both at rest and during exercise. We studied 90 patients (50 men) with a very low likelihood of coronary artery disease. Gated-SPECT MPI was performed with Tc-99m MIBI using a 2-day protocol, with 16 frames/R-R cycle. The LV ejection fraction and volumes were not different between the rest and post-stress images. LVEF was 68 ± 7% post-stress and 70 ± 7% at rest in women, and 62 ± 7% and 63 ± 7%, respectively, in men (P = .19, .26). LV volumes were larger in men than women (P stress. Transient ischemic dilatation was similar, with upper limits of 1.20 and 1.19 in women and men, respectively (P = NS). These data could prove helpful for the interpretation of gated SPECT MPI data in Latin America using identical protocol as used in this study.

  1. Experiencia en el aula de secundaria con fractales

    OpenAIRE

    Gallardo, Sandra; Martínez-Santaolalla, Manuel José; Molina, Marta; Peñas, María; Cañadas, María C.; Crisóstomo, Edson

    2006-01-01

    Presentamos una experiencia docente en un aula de 2º ESO en la que trabajamos los fractales mediante el uso de material de carácter manipulativo. La metodología seguida se basa en la construcción de casos particulares con el fin de llegar al concepto de fractal.

  2. Comparison of Gated SPECT Myocardial Perfusion Imaging with Echocardiography for the Measurement of Left Ventricular Volumes and Ejection Fraction in Patients With Severe Heart Failure

    Science.gov (United States)

    Shojaeifard, Maryam; Ghaedian, Tahereh; Yaghoobi, Nahid; Malek, Hadi; Firoozabadi, Hasan; Bitarafan-Rajabi, Ahmad; Haghjoo, Majid; Amin, Ahmad; Azizian, Nasrin; Rastgou, Feridoon

    2015-01-01

    Background: Gated single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is known as a feasible tool for the measurement of left ventricular ejection fraction (EF) and volumes, which are of great importance in the management and follow-up of patients with coronary artery diseases. However, considering the technical shortcomings of SPECT in the presence of perfusion defect, the accuracy of this method in heart failure patients is still controversial. Objectives: The aim of the present study was to compare the results from gated SPECT MPI with those from echocardiography in heart failure patients to compare echocardiographically-derived left ventricular dimension and function data to those from gated SPECT MPI in heart failure patients. Patients and Methods: Forty-one patients with severely reduced left ventricular systolic function (EF ≤ 35%) who were referred for gated SPECT MPI were prospectively enrolled. Quantification of EF, end-diastolic volume (EDV), and end-systolic volume (ESV) was performed by using quantitative gated spect (QGS) (QGS, version 0.4, May 2009) and emory cardiac toolbox (ECTb) (ECTb, revision 1.0, copyright 2007) software packages. EF, EDV, and ESV were also measured with two-dimensional echocardiography within 3 days after MPI. Results: A good correlation was found between echocardiographically-derived EF, EDV, and ESV and the values derived using QGS (r = 0.67, r = 0.78, and r = 0.80 for EF, EDV, and ESV, respectively; P echocardiography. ECTb-derived EDV was also significantly higher than the EDV measured with echocardiography and QGS. The highest correlation between echocardiography and gated SPECT MPI was found for mean values of ESV different. Conclusions: Gated SPECT MPI has a good correlation with echocardiography for the measurement of left ventricular EF, EDV, and ESV in patients with severe heart failure. However, the absolute values of these functional parameters from echocardiography and gated

  3. [Influence of the professional experience of the clinical cardiologist on the adequacy of the clinical indications of myocardial perfusion gated-SPECT].

    Science.gov (United States)

    Dominguez-Rodriguez, Alberto; Avanzas, Pablo; Abreu-Gonzalez, Pedro; Sanchez Grande-Flecha, Alejandro; García-Baute, María Del Carmen; Gómez, María Ángeles

    2017-11-30

    During cardiology training, the cardiology fellow has to be trained in all things related to the indication, interpretation, and performing of nuclear cardiology studies using single photon emission computed tomography (SPECT). The aim of the present study was to analyse the relationship between the adequacy of indications of myocardial perfusion gated-SPECT and the years of experience since the completion of cardiology training. A descriptive, retrospective analysis was performed on a single-centre register, in which the indications (adequate or inadequate use) were recorded according to myocardial perfusion gated-SPECT guidelines, prescribed by cardiologists of a university hospital. A total of 950 gated-SPECT tests were analysed according to the appropriate or inadequate indication. The sample of study was distributed in quartiles (years) since the cardiologist finished the residency. Cardiologists with less than 10 years of clinical experience reported a higher proportion of gated-SPECT tests compared to the more experienced cardiologists (87.6 vs. 9.3%, P<.001). After adjusting for age, gender, and cardiovascular risk factors, the multivariate analysis showed that, for each year of experience after completion of cardiology training, the probability of adequately indicating the test (OR: 1.33, 95% CI: 1.29-1.38, P<.001) was statistically significant. The professional experience of the clinical cardiologist is the most important factor to perform an appropriate indication of gated-SPECT myocardial perfusion. Copyright © 2017 Instituto Nacional de Cardiología Ignacio Chávez. Publicado por Masson Doyma México S.A. All rights reserved.

  4. Evaluation of left ventricular ejection fraction from radial long-axis tomography. A new reconstruction algorithm for ECG-gated technetium-99m Sestamibi SPECT

    International Nuclear Information System (INIS)

    Tsujimura, Eiichiro; Kusuoka, Hideo; Uehara, Toshiisa

    1997-01-01

    Radial long-axis tomography can provide views similar to contrast left ventriculography (LVG) including the basal and apical areas of the left ventricle, not possible in routine short-axis tomography. We applied this method to ECG-gated Tc-99m Sestamibi (MIBI) myocardial SPECT images to estimate the left ventricular ejection fraction (LVEF). ECG-gated Tc-99m MIBI SPECT was performed with a temporal resolution of 10 frames per R-R interval. LVEF was calculated on the basis of left ventricular volume estimates at end diastole (ED) and end systole (ES) with using an ellipsoid body model. To validate this method, LVEF's derived from ECG-gated Tc-99m MIBI SPECT were compared with those from LVG in 11 patients with coronary artery disease. There was a close linear correlation between LVEF values calculated from Tc-99m MIBI SPECT and those from LVG (r=0.89, p<0.001), although the gated SPECT underestimated LVEF compared to LVG. The technique showed excellent reproducibility (intra-observer variability, r=0.96, p<0.001; inter-observer variability, r=0.71, p<0.005). The radial long-axis tomography technique gives a good estimate of LVEF, in agreement with estimates based on LVG. ECG-gated Tc-99m MIBI SPECT can, therefore, be applicable to assess myocardial perfusion and ventricular function at the same time. (author)

  5. Evaluation of left ventricular ejection fraction from radial long-axis tomography. A new reconstruction algorithm for ECG-gated technetium-99m Sestamibi SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Tsujimura, Eiichiro; Kusuoka, Hideo; Uehara, Toshiisa [Osaka Univ. (Japan). Faculty of Medicine] [and others

    1997-08-01

    Radial long-axis tomography can provide views similar to contrast left ventriculography (LVG) including the basal and apical areas of the left ventricle, not possible in routine short-axis tomography. We applied this method to ECG-gated Tc-99m Sestamibi (MIBI) myocardial SPECT images to estimate the left ventricular ejection fraction (LVEF). ECG-gated Tc-99m MIBI SPECT was performed with a temporal resolution of 10 frames per R-R interval. LVEF was calculated on the basis of left ventricular volume estimates at end diastole (ED) and end systole (ES) with using an ellipsoid body model. To validate this method, LVEF`s derived from ECG-gated Tc-99m MIBI SPECT were compared with those from LVG in 11 patients with coronary artery disease. There was a close linear correlation between LVEF values calculated from Tc-99m MIBI SPECT and those from LVG (r=0.89, p<0.001), although the gated SPECT underestimated LVEF compared to LVG. The technique showed excellent reproducibility (intra-observer variability, r=0.96, p<0.001; inter-observer variability, r=0.71, p<0.005). The radial long-axis tomography technique gives a good estimate of LVEF, in agreement with estimates based on LVG. ECG-gated Tc-99m MIBI SPECT can, therefore, be applicable to assess myocardial perfusion and ventricular function at the same time. (author)

  6. Papel de la experiencia en la aceptación vs. rechazo del paciente con esquizofrenia

    OpenAIRE

    Carmen Senra-Rivera; Alessandra de Arriba-Rossetto; Gloria Seoane-Pesqueira

    2008-01-01

    En esta investigación se analiza la influencia que pueden tener distintos tipos y grados de experiencia con la enfermedad mental en la aceptación vs. rechazo del paciente con esquizofrenia. Participaron en el estudio 236 estudiantes universitarios que cumplimentaron una escala de distancia social relacionada con una viñeta en la que se describe un episodio psicótico de un paciente (hombre o mujer) con esquizofrenia y una escala que evalúa distintos tipos y grados de experiencia co...

  7. Impact of attenuation correction and gated acquisition in SPECT myocardial perfusion imaging: results of the multicentre SPAG (SPECT Attenuation Correction vs Gated) study

    International Nuclear Information System (INIS)

    Genovesi, Dario; Giorgetti, Assuero; Gimelli, Alessia; Kusch, Annette; D'Aragona Tagliavia, Irene; Casagranda, Mirta; Marzullo, Paolo; Cannizzaro, Giorgio; Giubbini, Raffaele; Bertagna, Francesco; Fagioli, Giorgio; Rossi, Massimiliano; Romeo, Annadina; Bertolaccini, Pietro; Bonini, Rita

    2011-01-01

    In clinical myocardial single photon emission computed tomography (SPECT), attenuation artefacts may cause a loss of specificity in the identification of diseased vessels that can be corrected by means of gated SPECT (GSPECT) acquisition or CT attenuation correction (AC). The purpose of this multicentre study was to assess the impact of GSPECT and AC on the diagnostic performance of myocardial scintigraphy, according to patient's sex, body mass index (BMI) and site of coronary artery disease (CAD). We studied a group of 104 patients who underwent coronary angiography within 1 month before or after the SPECT study. Patients with a BMI > 27 were considered ''overweight''. Attenuation-corrected and standard GSPECT early images were randomly interpreted by three readers blinded to the clinical data. In the whole group, GSPECT and AC showed a diagnostic accuracy of 86.5% (sensitivity 82%, specificity 93%) and 77% (sensitivity 75.4%, specificity 81.4%), respectively (p < 0.05). In women, when anterior ischaemia was matched with CAD, AC failed to show any increase in specificity (AC 63.6% vs GSPECT 63.6%) with evident loss of sensitivity (AC 72.7% vs GSPECT 90.9%). AC significantly improved SPECT specificity in the identification of right CAD in overweight men (AC 100% vs GSPECT 66.7%, p <0.05). AC improved specificity in the evaluation of right CAD in overweight men. In the other evaluable subgroups specificity was not significantly affected while sensitivity was frequently reduced. (orig.)

  8. Impact of attenuation correction and gated acquisition in SPECT myocardial perfusion imaging: results of the multicentre SPAG (SPECT Attenuation Correction vs Gated) study

    Energy Technology Data Exchange (ETDEWEB)

    Genovesi, Dario; Giorgetti, Assuero; Gimelli, Alessia; Kusch, Annette; D' Aragona Tagliavia, Irene; Casagranda, Mirta; Marzullo, Paolo [Fondazione CNR-Regione Toscana ' ' G. Monasterio' ' , Nuclear Medicine, Pisa (Italy); Cannizzaro, Giorgio [A.O.V. Cervello, Nuclear Medicine, Palermo (Italy); Giubbini, Raffaele; Bertagna, Francesco [Spedali Civili, Nuclear Medicine, Brescia (Italy); Fagioli, Giorgio; Rossi, Massimiliano; Romeo, Annadina [Ospedale Maggiore, Nuclear Medicine, Bologna (Italy); Bertolaccini, Pietro; Bonini, Rita [Ospedale SS Giacomo e Cristoforo, Nuclear Medicine, Massa (Italy)

    2011-10-15

    In clinical myocardial single photon emission computed tomography (SPECT), attenuation artefacts may cause a loss of specificity in the identification of diseased vessels that can be corrected by means of gated SPECT (GSPECT) acquisition or CT attenuation correction (AC). The purpose of this multicentre study was to assess the impact of GSPECT and AC on the diagnostic performance of myocardial scintigraphy, according to patient's sex, body mass index (BMI) and site of coronary artery disease (CAD). We studied a group of 104 patients who underwent coronary angiography within 1 month before or after the SPECT study. Patients with a BMI > 27 were considered ''overweight''. Attenuation-corrected and standard GSPECT early images were randomly interpreted by three readers blinded to the clinical data. In the whole group, GSPECT and AC showed a diagnostic accuracy of 86.5% (sensitivity 82%, specificity 93%) and 77% (sensitivity 75.4%, specificity 81.4%), respectively (p < 0.05). In women, when anterior ischaemia was matched with CAD, AC failed to show any increase in specificity (AC 63.6% vs GSPECT 63.6%) with evident loss of sensitivity (AC 72.7% vs GSPECT 90.9%). AC significantly improved SPECT specificity in the identification of right CAD in overweight men (AC 100% vs GSPECT 66.7%, p <0.05). AC improved specificity in the evaluation of right CAD in overweight men. In the other evaluable subgroups specificity was not significantly affected while sensitivity was frequently reduced. (orig.)

  9. ¿Con qué saboreamos?: tareas y experiencias para un taller de ciencias

    Directory of Open Access Journals (Sweden)

    Sánchez Ramos, M.A.

    2008-04-01

    Full Text Available En un grupo de primero de primaria hicimos una pregunta aparentemente simple: ¿Con qué saboreamos? La respuesta inmediata entre los niños fue “con la lengua” y, aunque ésta no fue totalmente correcta, sirvió para iniciar un proyecto en el que se ofreció a los niños la oportunidad para observar, proponer hipótesis, establecerobjetivos y buscar métodos que les ayudaran a resolver la pregunta. Planteamos 4 experiencias cuya finalidad fue que los niños extendieran sus conocimientos y su comprensión sobre un proceso aparentemente sencillo como es la percepción al sabor. Primero cuestionamos la idea de que fuera la lengua el lugar primordial para la detección del sabor (experiencia 1; después incluimos al sentido del olfato como parte de la percepción del sabor (experiencia 2; tratamos de convencer a los niños de que el olor es el elemento más importante para detectar el sabor (experiencia 3; por último discutimos la posibilidad de que fuera el cerebro el que realmente saborea (experiencia 4.

  10. ¿Con qué saboreamos?: tareas y experiencias para un taller de ciencias

    Directory of Open Access Journals (Sweden)

    Marco A. Sánchez Ramos

    2008-01-01

    Full Text Available En un grupo de primero de primaria hicimos una pregunta aparentemente simple: ¿Con qué saboreamos? La respuesta inmediata entre los niños fue "con la lengua" y, aunque ésta no fue totalmente correcta, sirvió para iniciar un proyecto en el que se ofreció a los niños la oportunidad para observar, proponer hipótesis, establecer objetivos y buscar métodos que les ayudaran a resolver la pregunta. Planteamos 4 experiencias cuya finalidad fue que los niños extendieran sus conocimientos y su comprensión sobre un proceso aparentemente sencillo como es la percepción al sabor. Primero cuestionamos la idea de que fuera la lengua el lugar primordial para la detección del sabor (experiencia 1; después incluimos al sentido del olfato como parte de la percepción del sabor (experiencia 2; tratamos de convencer a los niños de que el olor es el elemento más importante para detectar el sabor (experiencia 3; por último discutimos la posibilidad de que fuera el cerebro el que realmente saborea (experiencia 4.

  11. Serial assessment of left ventricular function in various patient groups with Tl-201 gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Wei Lingge; Kadoya, Masumi; Momose, Mitsuhiro; Kurozumi, Masahiro; Matsushita, Tsuyoshi; Yamada, Akira

    2007-01-01

    The present study was performed to assess stress-related left ventricular (LV) function variations in various patient groups and to determine if they were affected by sex or the type of stress experienced. We used thallium (Tl)-201 gated myocardial perfusion single-photon emission computed tomography (SPECT) for the analysis. A total of 270 patients were examined by electrocardiography-gated myocardial perfusion SPECT imaging to assess LV function. After injection of Tl-201 at a dose of 111 MBq at peak stress, SPECT scans were acquired at 10 min (after stress) and 3 h (rest) after injection on a three-headed camera. In the normal perfusion group, the mean LV ejection fraction (LVEF) was significantly higher, and both the end-diastolic volume index (EDVI) and end-systolic volume index (ESVI) were significantly lower in women than in men (P<0.05). Poststress stunning occurred in 29 of 98 patients (30.0%) in the ischemia group and in 42 of 90 patients (46.7%) in the fixed group. There was a significant difference in poststress stunning between bicycle ergometer stress and dipyridamole stress (P<0.05). In patients with normal perfusion, LVEF, EDVI, and ESVI determined by gated Tl-201 SPECT should be corrected for sex. In addition, the influence of the type of stress should be considered when assessing stress-related LV function variations. (author)

  12. Prognostic value of gated 201Tl myocardial perfusion SPECT imaging in patients with coronary artery disease

    International Nuclear Information System (INIS)

    Li Zicheng; Chen Xiaoming; Xu Hao

    2006-01-01

    Objective: To study the prognostic value of gated 201 Tl myocardial perfusion SPECT imaging in patients with coronary artery disease and assessment of therapy strategy for the individual patient. Methods: Eighty-four patients underwent rest and exercise stress 201 Tl gated myocardial perfusion SPECT imaging and were followed up for (32.92 ± 16.77) months. Images were studied using 17 segments and 1 to 4 scoring. Global summed stress score (SSS), summed rest score (SRS) and summed difference score (SDS=SSS-SRS) were also calculated. Post-stress and rest ejection fraction (EF) were automatically measured. Results: Nine cardiac events occurred (3.90% per year). SSS, SDS, SRS and EF were the independent predictors of cardiac events (P 201 Tl myocardial perfusion SPECT imaging can provide prognostic assessment for the patients with coronary artery disease and guide in selection of therapeutic strategy. Among all of the indices SSS is the best predictors of cardiac events. (authors)

  13. Assessment of left ventricular function by thallium-201 quantitative gated cardiac SPECT

    International Nuclear Information System (INIS)

    Baba, Akira; Hano, Takuzo; Ohmori, Hisashi; Ibata, Masayo; Kawabe, Tetsuya; Kubo, Takashi; Kimura, Keizo; Nishio, Ichiro

    2002-01-01

    Present study was designed to evaluate the accuracy of the measurement of left ventricular volume by quantitative gated SPECT (QGS) software using 201 Tl and the effect of cutoff frequency of Butterworth prereconstruction filter on the calculation of volume. The RH-2 type cardiac phantom and 20 patients with ischemic heart disease were studied. Left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were calculated by the QGS software using the various frequency of Butterworth filter. These parameters were evaluated by Simpson's method using left ventriculography (LVG). The volume of the phantom calculated by QGS was under-estimated by 14%. In the clinical study, EDV and ESV measured by QGS were smaller than those obtained from LVG by 10%. When the cutoff frequency of Butterworth filter was 0.43 cycles/cm, the values measured by QGS were best correlated with those by LVG (EDV: r=0.80, p 201 Tl quantitative gated cardiac SPECT can estimate myocardial ischemia and left ventricular function simultaneously. (author)

  14. Experiencia sobre desarrollo con Genexus siguiendo prácticas ágiles

    OpenAIRE

    Gimson Saravia, Loraine Elizabeth; Gil, Gustavo Daniel

    2016-01-01

    Este trabajo busca describir la experiencia realizada con alumnos del último año de la Licenciatura en Análisis de Sistemas de la Universidad Nacional de Salta combinando el desarrollo basado en conocimiento (DBC), utilizando Genexus, con un desarrollo ágil. Se pretendió brindarles una práctica real de aplicar los principios ágiles a los alumnos combinando su aplicación con Genexus a dos proyectos concretos.

  15. Physics process level discrimination of detections for GATE: assessment of contamination in SPECT and spurious activity in PET.

    Science.gov (United States)

    De Beenhouwer, Jan; Staelens, Steven; Vandenberghe, Stefaan; Verhaeghe, Jeroen; Van Holen, Roel; Rault, Erwann; Lemahieu, Ignace

    2009-04-01

    The GEANT4 application for tomographic emission (GATE) is one of the most detailed Monte Carlo simulation tools for SPECT and PET. It allows for realistic phantoms, complex decay schemes, and a large variety of detector geometries. However, only a fraction of the information in each particle history is available for postprocessing. In order to extend the analysis capabilities of GATE, a flexible framework was developed. This framework allows all detected events to be subdivided according to their type: In PET, true coincidences from others, and in SPECT, geometrically collimated photons from others. The framework of the authors can be applied to any isotope, phantom, and detector geometry available in GATE. It is designed to enhance the usability of GATE for the study of contamination and for the investigation of the properties of current and future prototype detectors. The authors apply the framework to a case study of Bexxar, first assuming labeling with 124I, then with 131I. It is shown that with 124I PET, results with an optimized window improve upon those with the standard window but achieve less than half of the ideal improvement. Nevertheless, 124I PET shows improved resolution compared to 131I SPECT with triple-energy-window scatter correction.

  16. A priori motion models for four-dimensional reconstruction in gated cardiac SPECT

    International Nuclear Information System (INIS)

    Lalush, D.S.; Tsui, B.M.W.; Cui, Lin

    1996-01-01

    We investigate the benefit of incorporating a priori assumptions about cardiac motion in a fully four-dimensional (4D) reconstruction algorithm for gated cardiac SPECT. Previous work has shown that non-motion-specific 4D Gibbs priors enforcing smoothing in time and space can control noise while preserving resolution. In this paper, we evaluate methods for incorporating known heart motion in the Gibbs prior model. The new model is derived by assigning motion vectors to each 4D voxel, defining the movement of that volume of activity into the neighboring time frames. Weights for the Gibbs cliques are computed based on these open-quotes most likelyclose quotes motion vectors. To evaluate, we employ the mathematical cardiac-torso (MCAT) phantom with a new dynamic heart model that simulates the beating and twisting motion of the heart. Sixteen realistically-simulated gated datasets were generated, with noise simulated to emulate a real Tl-201 gated SPECT study. Reconstructions were performed using several different reconstruction algorithms, all modeling nonuniform attenuation and three-dimensional detector response. These include ML-EM with 4D filtering, 4D MAP-EM without prior motion assumption, and 4D MAP-EM with prior motion assumptions. The prior motion assumptions included both the correct motion model and incorrect models. Results show that reconstructions using the 4D prior model can smooth noise and preserve time-domain resolution more effectively than 4D linear filters. We conclude that modeling of motion in 4D reconstruction algorithms can be a powerful tool for smoothing noise and preserving temporal resolution in gated cardiac studies

  17. Improved accuracy in estimation of left ventricular function parameters from QGS software with Tc-99m tetrofosmin gated-SPECT. A multivariate analysis

    International Nuclear Information System (INIS)

    Okizaki, Atsutaka; Shuke, Noriyuki; Sato, Junichi; Ishikawa, Yukio; Yamamoto, Wakako; Kikuchi, Kenjiro; Aburano, Tamio

    2003-01-01

    The purpose of this study was to verify whether the accuracy of left ventricular parameters related to left ventricular function from gated-SPECT improved or not, using multivariate analysis. Ninety-six patients with cardiovascular diseases were studied. Gated-SPECT with the quantitative gated SPECT (QGS) software and left ventriculography (LVG) were performed to obtain left ventricular ejection fraction (LVEF), end-diastolic volume (EDV) and end-systolic volume (ESV). Then, multivariate analyses were performed to determine empirical formulas for predicting these parameters. The calculated values of left ventricular parameters were compared with those obtained directly from the QGS software and LVG. Multivariate analyses were able to improve accuracy in estimation of LVEF, EDV and ESV. Statistically significant improvement was seen in LVEF (from r=0.6965 to r=0.8093, p<0.05). Although not statistically significant, improvements in correlation coefficients were seen in EDV (from r=0.7199 to r=0.7595, p=0.2750) and ESV (from r=0.5694 to r=0.5871, p=0.4281). The empirical equations with multivariate analysis improved the accuracy in estimating LVEF from gated-SPECT with the QGS software. (author)

  18. Límite fino y transliminalidad en relación con experiencias aparicionales y sensación de presencia

    Directory of Open Access Journals (Sweden)

    Alejandro Parra

    2017-01-01

    Full Text Available Objetivo. Comparar la transliminalidad y el límite fi no en personas que tienen experiencias de apariciones y sensación de presencia con un grupo control. Se plantea como hipótesis que las personas que reportan experiencias aparicionales y sensación de presencia tienen: (a mayor propensión a tener experiencias anómalas, (b mayor transliminalidad y (c límites más fi nos en comparación con un grupo control. Método.Se administraron cuatro medidas, la Escala Cardiff de Percepciones Anómalas, la Escala de Transliminalidad (revisada, el Inventario de Experiencias Anómalo/Paranormales y el Cuestionario de Límites, a una muestra compuesta por 203 participantes interesados en experiencias paranormales (151 mujeres y 52 hombres. Resultados. Se confi rmaron las tres hipótesis, esto es, mayor nivel de experiencias anómalas, transliminalidad y límite más fi no en individuos que reportan la experiencia en comparación con quienes no las reportan.Conclusión. Estos resultados indican que, particularmente, el constructo de límite fi no refl eja unos procesos atencionales o hiperestesia particular para la detección del entorno en aquellos involucrados en presuntas experiencias aparicionales.

  19. Utility of QGS for 201Tl electrocardiogram-gated SPECT in cardiac function evaluations

    International Nuclear Information System (INIS)

    Shimazaki, Hiroshi; Oono, Ryuichi

    2001-01-01

    QGS (quantitative gated SPECT) was applied to 201 Tl SPECT, whose images are inferior to those of Tc SPECT, and its utility was evaluated. More specifically, the cardiac function index was calculated by QGS, and local wall motion was evaluated visually. Accuracy was assessed by comparison with left ventriculography. The subjects were 29 patients (21 males, 8 females; 6 with myocardial infarction, 18 with stenocardia, 2 with pericardial disease, 3 with other heart diseases) who had undergone myocardial scintigraphy and left ventriculography between February and May, 2000. 201 Tl (74 or 111 MBq) was administered to all patients. The resting image was obtained 10 minutes later, and the delayed image during loading was obtained 4 hours later. The conditions for acquiring the images were as follows. Two detectors were arranged at a 90-degree angle in the form of an L. The 180 degrees from 45 degrees right anterior oblique (RAO) to 45 degrees left posterior oblique (LPO) were divided into 30 sections at 6-degree intervals, and the image in each section was acquired for 60 seconds. The matrix was 64 x 64. As a cardiac function index, the left ventricular ejection function (LVEF) obtained by electrocardiogram-gated SPECT (QGS-EF) at the rest (14 cases) and the QGS-EF on the delayed images (15 cases) were compared with the LVEF determined by left ventriculography (LVG-EF). There was an excellent positive correlation between the data obtained by two methods, with a correlation coefficient of r=0.93 (y=1.04x-0.04). Most of the difference between the values fell within two standard deviations, and the error was in the clinically allowable range. There was no significant difference between the correlation coefficient at rest and during loading or between the cases that showed an obvious defect on the image and those that did not. The local wall motion of the left ventricle was visually evaluated in five stages in two directions (RAO, 30 degrees, and LAO, 60 degrees). The motion

  20. Assessment of left ventricular performance by ECG-gated SPECT. Comparison with magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tadamura, Eiji; Inubushi, Masayuki; Kubo, Shigeto; Matsumoto, Keiichi; Yokoyama, Hiroshi; Fujita, Toru; Konishi, Junji [Kyoto Univ. (Japan). Faculty of Medicine

    1999-10-01

    In the measurement of a left ventricular volume, MIBI-QGS was compared with MRI. Because it became clear by the experiment using phantom that a volume calculated with QGS was smaller than the actual volume, data of clinical study were corrected. Subjects were 20 patients with coronary artery disease. Fourteen patients had anamnesis of myocardial infarct. ECG-gated SPECT was performed one hour after intravenous injection of MIBI (600 MBq) in rest. End diastolic volume (EDV), end systolic volume (ESV) and ejection fraction (EF) were calculated using QGS. Cine-MR image was obtained by using MR system of 1.5 Tesla within 1 week after SPECT. A condition was as follows; segmented k-space gradient echo with view sharing, TR=11 ms, TE=1.4 ms, flip angle 20 degree, field of view 32 cm, matrix 256 x 196, 8 lines per segment. LVEF, ESV and EF were analysed by Bland-Altman method, and the difference between MIBI-gated-SPECT and MRI was no problem. Horizontal dislocation image and vertical major axis dislocation image were provided. Minor axis crossing images of 10-12 slice were also filmed in order to cover all left ventricles. As a result, availability of MIBI-QGS became clear. Some factors which produces the measurement error are examined. (K.H.)

  1. Electrocardiographic-gated dual-isotope simultaneous acquisition SPECT using 18F-FDG and 99mTc-sestamibi to assess myocardial viability and function in a single study

    International Nuclear Information System (INIS)

    Matsunari, Ichiro; Matsudaira, Masamichi; Hisada, Kinichi; Kanayama, Sugako; Yoneyama, Tatsuya; Nakajima, Kenichi; Taki, Junichi; Tonami, Norihisa; Nekolla, Stephan G.

    2005-01-01

    Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18 F-fluorodeoxyglucose (FDG) and 99m Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benefit of this approach is that the measurement of left ventricular (LV) function may be possible by ECG gating. The aim of this study was to test the hypothesis that both myocardial viability and LV function can be assessed by a single ECG-gated 18 F-FDG/ 99m Tc-sestamibi DISA SPECT study, based on comparison with 18 F-FDG/ 13 N-ammonia positron emission tomography (PET) and magnetic resonance imaging (MRI) as reference techniques. Thirty-three patients with prior myocardial infarction underwent ECG-gated 18 F-FDG/ 99m Tc-sestamibi DISA SPECT and 18 F-FDG/ 13 N-ammonia PET on a single day. Of these, 25 patients also underwent cine-MRI to assess LV function. The LV myocardium was divided into nine regions, and each region was classified as viable or scar using a semiquantitative visual scoring system as well as quantitative analysis. The global and regional LV function measured by gated SPECT was compared with the results of MRI. There was good agreement in respect of viability (90-96%, κ0.74-0.85) between DISA SPECT and PET by either visual or quantitative analysis. Furthermore, although both global and regional LV function measured by gated SPECT agreed with those by MRI, 99m Tc-sestamibi showed a closer correlation with MRI than did 18 F-FDG. In conclusion, ECG-gated DISA SPECT provides information on myocardial viability, as well as global and regional LV function, similar to that obtained by PET and MRI. (orig.)

  2. Assessment of left ventricular function by thallium-201 quantitative gated cardiac SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Akira; Hano, Takuzo; Ohmori, Hisashi; Ibata, Masayo; Kawabe, Tetsuya; Kubo, Takashi; Kimura, Keizo; Nishio, Ichiro [Wakayama Medical Coll. (Japan)

    2002-02-01

    Present study was designed to evaluate the accuracy of the measurement of left ventricular volume by quantitative gated SPECT (QGS) software using {sup 201}Tl and the effect of cutoff frequency of Butterworth prereconstruction filter on the calculation of volume. The RH-2 type cardiac phantom and 20 patients with ischemic heart disease were studied. Left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were calculated by the QGS software using the various frequency of Butterworth filter. These parameters were evaluated by Simpson's method using left ventriculography (LVG). The volume of the phantom calculated by QGS was under-estimated by 14%. In the clinical study, EDV and ESV measured by QGS were smaller than those obtained from LVG by 10%. When the cutoff frequency of Butterworth filter was 0.43 cycles/cm, the values measured by QGS were best correlated with those by LVG (EDV: r=0.80, p<0.001; ESV: r=0.86, p<0.001; EF: r=0.80, p<0.001). These data suggest that {sup 201}Tl quantitative gated cardiac SPECT can estimate myocardial ischemia and left ventricular function simultaneously. (author)

  3. GATE simulation of a LYSO-based SPECT imager: Validation and detector optimization

    International Nuclear Information System (INIS)

    Li, Suying; Zhang, Qiushi; Xie, Zhaoheng; Liu, Qi; Xu, Baixuan; Yang, Kun; Li, Changhui; Ren, Qiushi

    2015-01-01

    This paper presents a small animal SPECT system that is based on cerium doped lutetium–yttrium oxyorthosilicate (LYSO) scintillation crystal, position sensitive photomultiplier tubes (PSPMTs) and parallel hole collimator. Spatial resolution test and animal experiment were performed to demonstrate the imaging performance of the detector. Preliminary results indicated a spatial resolution of 2.5 mm at FWHM that cannot meet our design requirement. Therefore, we simulated this gamma camera using GATE (GEANT 4 Application for Tomographic Emission) aiming to make detector spatial resolution less than 2 mm. First, the GATE simulation process was validated through comparison between simulated and experimental data. This also indicates the accuracy and effectiveness of GATE simulation for LYSO-based gamma camera. Then the different detector sampling methods (crystal size with 1.5, and 1 mm) and collimator design (collimator height with 30, 34.8, 38, and 43 mm) were studied to figure out an optimized parameter set. Detector sensitivity changes were also focused on with different parameters set that generated different spatial resolution results. Tradeoff curves of spatial resolution and sensitivity were plotted to determine the optimal collimator height with different sampling methods. Simulation results show that scintillation crystal size of 1 mm and collimator height of 38 mm, which can generate a spatial resolution of ∼1.8 mm and sensitivity of ∼0.065 cps/kBq, can be an ideal configuration for our SPECT imager design

  4. Comparison of Nitrate-augmented resting gated 99mTc-Sestamibi imaging with Low Dose Dobutamine SPECT for the detection of Myocardial Viability

    International Nuclear Information System (INIS)

    Parameswaran, R.V.; Dash, P.K.; Barooah, B.; Guruprasad, H.P.; Purantharan, N.

    2002-01-01

    Background: Dobutamine Echocardiography and Radionuclide imaging with Tl-201 and Technetium agents are two of the most established techniques available for the detection of viable myocardium. The purpose of this study was to evaluate the utility of Low dose Dobutamine gated Myocardial SPECT in identifying additional areas of dysfunctional, but viable myocardium when compared to nitrate-augmented rest gated SPECT with SestaMIBI. Materials and Methods: 20 patients (19 males and 1 female, with an age range of 40- 65 yrs and a mean of 52.75yrs) all with history of MI or severe LV dysfunction were included in this study. Patients with LBBB, recent revascularisation, arrhythmias etc were excluded from the study. A routine stress-rest study was initially performed on them with 99mTc-SestaMIBI and both the stress as well as resting studies was gated and the resting study was augmented with 10mg of sublingual nitrate. After the resting study was over, the patient was infused with Low dose Dobutamine(5μg/kg/min), at which time the gated acquisition was started and the infusion was continued till the acquisition got completed. In the perfusion study with SestaMIBI, all infarct segments which have uptake less than 50% as compared to the maximally perfused area was deemed non-viable Results: A 17-segment Myocardial model was used for both perfusion as well as quantification of wall motion and wall thickening. 110 akinetic/dyskinetic segments were taken up for analysis. 93 of these segments were non-viable and improvement in wall motion was seen in 17 segments (15.4%) in the nitrate-augmented SPECT. Dobutamine study showed improvement in totally in 27 segments (24.5%), 10 of which were additional segments which were non-viable in Nitrate SPECT study, apart from the 17 segments which showed improvement in the Nitrate study. In Dobutamine study, there was also improvement in wall thickening in 10 (10.7%) out of 93 segments which had showed less than 50% of MIBI uptake. Conclusion

  5. Diagnosis of silent myocardial ischemia in type 2 diabetic patients by electrocardiogram, ergometry and Gated-SPECT

    International Nuclear Information System (INIS)

    Penna Quian, Yamile; Fernandez-Britto Rodriguez, Jose; Bacallao Gallestey, Jorge; Batista Cuellar, Juan Felipe; Coca Perez, Marco Antonio; Toirac Garcia, Noresma; Penna Coego, Andria

    2008-01-01

    31 asymptomatic type 2 diabetic patients were studied by lab tests, electrocardiogram, ergometry, Gated-SPECT and coronariography to determine the relation between the atherosclerotic risk factors and the silent myocardial ischemia. Patients were classified into two groups: positive SPECT and negative SPECT. Association tests were made for each variable and ROC curves were constructed to identify risk markers. In 35.5% of the patients silent myocardial ischemia was detected with a good angiographic correlation. A significant association was evidenced between positive SPECT and the atherosclerotic risk factors, namely, low values of HDLc, family pathological history of ischemic heart disease and peripheral vascular disease. The logistic regression models showed that low values of HDLc together with family pathological history of ischemic heart disease may be strong predictors of silent myocardial ischemia in asymptomatic type 2 diabetic patients

  6. Automated quantitative coronary computed tomography correlates of myocardial ischaemia on gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Graaf, Michiel A. de; Boogers, Mark J.; Veltman, Caroline E.; El-Naggar, Heba M.; Bax, Jeroen J.; Delgado, Victoria; Broersen, Alexander; Kitslaar, Pieter H.; Dijkstra, Jouke; Kroft, Lucia J.; Younis, Imad Al; Reiber, Johan H.; Scholte, Arthur J.

    2013-01-01

    Automated software tools have permitted more comprehensive, robust and reproducible quantification of coronary stenosis, plaque burden and plaque location of coronary computed tomography angiography (CTA) data. The association between these quantitative CTA (QCT) parameters and the presence of myocardial ischaemia has not been explored. The aim of the present investigation was to evaluate the association between QCT parameters of coronary artery lesions and the presence of myocardial ischaemia on gated myocardial perfusion single-photon emission CT (SPECT). Included in the study were 40 patients (mean age 58.2 ± 10.9 years, 27 men) with known or suspected coronary artery disease (CAD) who had undergone multidetector row CTA and gated myocardial perfusion SPECT within 6 months. From the CTA datasets, vessel-based and lesion-based visual analyses were performed. Consecutively, lesion-based QCT was performed to assess plaque length, plaque burden, percentage lumen area stenosis and remodelling index. Subsequently, the presence of myocardial ischaemia was assessed using the summed difference score (SDS ≥2) on gated myocardial perfusion SPECT. Myocardial ischaemia was seen in 25 patients (62.5 %) in 37 vascular territories. Quantitatively assessed significant stenosis and quantitatively assessed lesion length were independently associated with myocardial ischaemia (OR 7.72, 95 % CI 2.41-24.7, p 2 = 20.7) and lesion length (χ 2 = 26.0) to the clinical variables and the visual assessment (χ 2 = 5.9) had incremental value in the association with myocardial ischaemia. Coronary lesion length and quantitatively assessed significant stenosis were independently associated with myocardial ischaemia. Both quantitative parameters have incremental value over baseline variables and visually assessed significant stenosis. Potentially, QCT can refine assessment of CAD, which may be of potential use for identification of patients with myocardial ischaemia. (orig.)

  7. Pulse wave as an alternate signal for data synchronization during gated myocardial perfusion SPECT imaging.

    Science.gov (United States)

    Lang, Otto; Trojanova, Helena; Balon, Helena R; Kunikova, Ivana; Bilwachs, Milos; Penicka, Martin; Kaminek, Milan; Myslivecek, Miroslav

    2011-09-01

    Proper identification of the cardiac cycle is essential for gated SPECT myocardial perfusion imaging. We have developed an alternate method of ECG for gating, that is, using the peripheral pulse wave (PW) as the triggering signal for gated SPECT acquisition. The aim of this study is to compare the use of this method of gating with the standard ECG trigger. We tested the PW triggering by comparing it with the ECG trigger. We evaluated 33 patients (25 males, 8 females), average age of 61 years (39-80) referred for stress myocardial perfusion imaging. Data from all patients were acquired twice and were processed by CEqual and QGS software. We compared the left ventricular ejection fraction (LVEF), end-diastolic and end-systolic volumes (EDV, ESV). Paired t test and Pearson correlation coefficient were used for comparison. The mean LVEF, EDV, and ESV calculated with the ECG trigger were 0.52, 120, and 64, respectively, those with the pulse-wave trigger were 0.48, 126, and 71, respectively. Mean paired difference for LVEF was -0.034 (P<0.001), for EDV 5.9 (P=0.012), and for ESV 7.9 (P<0.001). Pearson correlation coefficient for LVEF was 0.955, for EDV 0.987, and for ESV 0.991 (P<0.001 for all correlations). Triggering of gated-data acquisition by the PW is feasible. Quantitative parameters of cardiac function correlate highly with those obtained from the ECG trigger and the absolute differences are not clinically significant across a wide range of values.

  8. Myocardial viability assessment with gated SPECT Tc-99m tetrofosmin % wall thickening. Comparison with F-18 FDG-PET

    International Nuclear Information System (INIS)

    Maruyama, Atsushi; Hasegawa, Shinji; Paul, A.K.; Xiuli, M.; Yoshioka, Jun; Maruyama, Kaoru; Hori, Masatsugu; Nishimura, Tsunehiko

    2002-01-01

    This study was designed to assess the value of gated SPECT Tc-99m-tetrofosmin (TF) wall thickening (WT) in addition to TF exercise (Ex)/rest myocardial SPECT, in comparison with F-18 fluorodeoxyglucose (FDG)-PET. The study population consisted of 33 patients with old myocardial infarction (27 men and 6 women; mean age, 62±8 years old). All patients underwent Ex/rest TF SPECT and glucose loading FDG-PET. Polar map images of Ex/rest TF were generated and divided into 24 segments for further analysis. We classified LV segments according to the exercise-rest perfusion scintigraphy. LV segments with less than 70% of the maximum TF activity on the exercise image were defined as stress-induced defects. Among these, the segments whose TF acitvity increased by 10% from exercise to rest images or exceeded 70% of the maximum uptake were defined as reversible (viable) defects. The remaining defects on the rest image were irreversible (non-viable) defect segments, and were considered for viability study on the basis of %WT. %WT was calculated according to the standard method: {(counts ES-counts ED)/ counts ED} x 100. A viable segment on gated SPECT was defined as a segment whose %WT exceeded the lower limit of the normal value (mean-SD). PET viability was defined as FDG uptake exceeding 50% of the maximum count. Among the 792 segments evaluated in the 33 patients studied, there were 689 PET viable segments. Of the 689 segments analyzed, 198 (29%) were identified as having defects on Ex images. Among these defects, 55 (8%) were reversible or partially reversible, as evidenced by rest images, and 143 (21%) were irreversible. Of the irreversible segments on Ex/rest images, 106 (15%) demonstrated no apparent WT by gated TF SPECT, whereas 37 (6%) segments with irreversible defects did have apparent WT. Overall, the sensitivity of Ex/rest TF perfusion imaging was 79%. Sensitivity was improved from 79% to 85% by combining %WT and perfusion data, but specificity was reduced from 70

  9. Prediction of functional recovery after revascularization using quantitative gated myocardial perfusion SPECT: a multi-center cohort study in Japan

    International Nuclear Information System (INIS)

    Nakajima, Kenichi; Tamaki, Nagara; Kuwabara, Yoichi; Kawano, Masaya; Matsunari, Ichiro; Taki, Junichi; Nishimura, Shigeyuki; Yamashina, Akira; Ishida, Yoshio; Tomoike, Hitonobu

    2008-01-01

    Prediction of left ventricular functional recovery is important after myocardial infarction. The impact of quantitative perfusion and motion analyses with gated single-photon emission computed tomography (SPECT) on predictive ability has not been clearly defined in multi-center studies. A total of 252 patients with recent myocardial infarction (n = 74) and old myocardial infarction (n = 175) were registered from 25 institutions. All patients underwent resting gated SPECT using 99m Tc-hexakis-2-methoxy-isobutyl isonitrile (MIBI) and repeated the study after revascularization after an average follow-up period of 132 ± 81 days. Visual and quantitative assessment of perfusion and wall motion were performed in 5,040 segments. Non-gated segmental percent uptake and end-systolic (ES) percent uptake were good predictors of wall motion recovery and significantly differed between improved and non-improved groups (66 ± 17% and 55 ± 18%, p 99m Tc-MIBI uptake provided a useful predictor of wall motion improvement. Application of quantitative approach with non-gated and ES percent uptake enhanced predictive accuracy over visual analysis particularly in a multi-center study. (orig.)

  10. Calculation of left ventricular volume and ejection fraction from ECG-gated myocardial SPECT. Automatic detection of endocardial borders by threshold method

    International Nuclear Information System (INIS)

    Fukushi, Shoji; Teraoka, Satomi.

    1997-01-01

    A new method which calculate end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (LVEF) of the left ventricle from myocardial short axis images of ECG-gated SPECT using 99m Tc myocardial perfusion tracer has been designed. Eight frames per cardiac cycle ECG-gated 180 degrees SPECT was performed. Threshold method was used to detect myocardial borders automatically. The optimal threshold was 45% by myocardial SPECT phantom. To determine if EDV, ESV and LVEF can also be calculated by this method, 12 patients were correlated ventriculography (LVG) for 10 days each. The correlation coefficient with LVG was 0.918 (EDV), 0.935 (ESV) and 0.900 (LVEF). This method is excellent at objectivity and reproductivity because of the automatic detection of myocardial borders. It also provides useful information on heart function in addition to myocardial perfusion. (author)

  11. Reversible wall motion abnormality on adenosine stress/rest thallium-201 gated myocardial SPECT is an independent predictor of coronary artery disease

    International Nuclear Information System (INIS)

    Park, Eun Kyung; Lee, Won Woo; So, Young; Eo, Jae Seon; Lee, Dong Soo; Chung, June Key; Lee, Myung Chul; Kim, Sang Eun; Kim, Cheol Ho; Lee, Sang Woo

    2004-01-01

    As early as 10 minutes after adenosine stress, immediate post-stress wall motion (ipsWM) can be evaluated on adenosine stress/rest TI-201 gated SPECT (gSPECT). To widen application of TI-201 in gated SPECT, we investigated image quality, LV parameters (EF, EDV, and ESV) reproducibility, and diagnostic competency of gSPECT regarding ipsWM evaluation Myocardial perfusion and wall motion were evaluated by 5-point scoring system in 20-segment model. Image quality was assessed using weighted Kappa (Kw) for inter-and intra-observer agreements of wall motion scores (n=49). Reproducibility was examined through repeated acquisition (n=31). Diagnostic competency was evaluated versus coronary angiography (CAG) and multivariate logistic regression analysis was performed to identify significant predictors of coronary artery disease (CAD) among stress abnormal perfusion (SSSp), stress abnormal wall motion (SSSwm), and reversible abnormal wall motion (SDSwm) (n=60). Kw for ipsWM was significantly better than that for rest regarding inter- (0.717 vs 0.489) and intra-observer agreements (0.792 vs 0.688) (p<0.05). 2SD for ipsWM was smaller than that for rest at EF (8.6% vs 10.7%) and ESV (6.0ml vs 8.4ml). Sensitivities of SSSp, SSSwm, and SDSwm were 63.3% (19/30), 63.3% (19/30), and 43.3% (13/30) and specificities 83.3% (25/30), 83.3% (25/30), and 86.7% (26/30), respectively. By multivariate analysis, SSSp (p=0.013) and SDSwm (p=0.039) remained significant predictors. Additionally, SSSwm or SDSwm could find undetected CAD in 54.5% (6/11) of patients with normal perfusion. TI-201 can be successfully applied to gated SPECT for ipsWM evaluation. Moreover, reversible wall motion abnormality on gSPECT is an independent predictor of significant CAD

  12. Prognostic value of Tc-99m tetrofosmin myocardial perfusion gated SPECT in patients with diabetes mellitus and suspected coronary artery disease

    International Nuclear Information System (INIS)

    Santos, Marcia Maria Sales dos; Pantoja, Mauricio da Rocha; Cwajg, Eduardo

    2008-01-01

    Background: The cardiovascular disease is the main cause of death among diabetic patients, which makes it crucial to identify the individuals at higher risk of cardiovascular events. Objective: To evaluate the prognostic value of scintigraphy with gated single photon emission computed tomography (SPECT) in patients with diabetes mellitus (DM) and suspected coronary artery disease. Methods: Retrospective study with 232 diabetic patients submitted to scintigraphy with gated SPECT. Perfusion Gated SPECT (scores and number of altered segments) as well as ventricular function parameters (ejection fraction, left ventricle volume and contractility) were evaluated. Cardiac death, acute ischemic coronary syndrome, revascularization procedures or encephalic vascular accident were considered future cardiovascular events. The uni- and multivariate analyses were carried out by the multiple logistic regression model (p< 0.05). Results: At the univariate analysis, age (p=0.02), chest angina (p=0.01), insulin therapy (p=0.02), myocardial perfusion abnormalities (p<0.0001), the number of segments involved (p=0.0001), the perfusion scores (p=0.0001), the ejection fraction (p=0.004), the final systolic volume (p=0.03) and the finding of segmental alteration at the LV contractility (p<0.0001) were associated with future events at the univariate analysis. At the multivariate analysis, the male sex (p=0.007), age (p=0.03), angina (p=0.001), insulin therapy (p=0.007) and the SDS ≥ 3 (p=0.0001), and the number of altered segments ≥ 3 (p=0.0001) were predictors of cardiovascular events. Conclusion: The myocardial scintigraphy with gated SPECT adds independent information to the stratification of the risk of future cardiovascular events in patients with DM and suspected coronary artery disease. (author)

  13. Prognostic value of Tc-99m tetrofosmin myocardial perfusion gated SPECT in patients with diabetes mellitus and suspected coronary artery disease

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Marcia Maria Sales dos; Pantoja, Mauricio da Rocha; Cwajg, Eduardo [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); CINTILAB, Rio de Janeiro, RJ (Brazil); E-mail: mmsales@oi.com.br

    2008-01-15

    Background: The cardiovascular disease is the main cause of death among diabetic patients, which makes it crucial to identify the individuals at higher risk of cardiovascular events. Objective: To evaluate the prognostic value of scintigraphy with gated single photon emission computed tomography (SPECT) in patients with diabetes mellitus (DM) and suspected coronary artery disease. Methods: Retrospective study with 232 diabetic patients submitted to scintigraphy with gated SPECT. Perfusion Gated SPECT (scores and number of altered segments) as well as ventricular function parameters (ejection fraction, left ventricle volume and contractility) were evaluated. Cardiac death, acute ischemic coronary syndrome, revascularization procedures or encephalic vascular accident were considered future cardiovascular events. The uni- and multivariate analyses were carried out by the multiple logistic regression model (p< 0.05). Results: At the univariate analysis, age (p=0.02), chest angina (p=0.01), insulin therapy (p=0.02), myocardial perfusion abnormalities (p<0.0001), the number of segments involved (p=0.0001), the perfusion scores (p=0.0001), the ejection fraction (p=0.004), the final systolic volume (p=0.03) and the finding of segmental alteration at the LV contractility (p<0.0001) were associated with future events at the univariate analysis. At the multivariate analysis, the male sex (p=0.007), age (p=0.03), angina (p=0.001), insulin therapy (p=0.007) and the SDS {>=} 3 (p=0.0001), and the number of altered segments {>=} 3 (p=0.0001) were predictors of cardiovascular events. Conclusion: The myocardial scintigraphy with gated SPECT adds independent information to the stratification of the risk of future cardiovascular events in patients with DM and suspected coronary artery disease. (author)

  14. Normal LVEF measurements are significantly higher in females asassessed by post-stress resting Tc-99m sestamibi gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Kim, Jong Ho; Shin, Eak Kyun

    1999-01-01

    Volume-LVEF relationship is one of the most important factors of automatic EF quantification algorithm from gated myocardial perfusion SPECT(gMPS) (Germano et al. JNM, 1995). Gender difference whereby normal LVEF measurements are higher in females assessed by gMPS (Yao et al. JNM 1997). To validate true physiologic value of LVEF vs sampling or measured error, various parameters were evaluated statistically in both gender and age matched 200 subjects (mean age= 58.41±15.01) with normal LVEF more than 50%, and a low likelihood of coronary artery disease. Correlation between LVEDVi(ml/m2) and LVEF was highly significant (r=-0.62, p<0.0001) with similar correlations noted in both male (r=-0.45, p<0.0001) and female (r=-0.67, p<0.0001) subgroups. By multivariate analysis, LV volume and stroke volume was the most significant factor influencing LVEF in male and female, respectively. In conclusion, there is a significant negative correlation between LV volume and LVEF as measured by Tc-99m gated SPECT. Higher normal LVEF value should be applied to females as assessed by post-stress resting Tc-99m Sestamibi gated myocardial perfusion SPECT

  15. Las experiencias extracorpóreas y las experiencias alucinatorias: relación con variables cognitivas y perceptuales

    Directory of Open Access Journals (Sweden)

    Alejandro Parra

    2008-12-01

    Full Text Available RESUMENLa experiencia fuera del cuerpo (EFC se define como un experiencia mediante la cual el “yo” o centro de conciencia parece ocupar una posición remota respecto a su propio cuerpo. Un total de 648 estudiantes de psicología que incluyó 78% de mujeres y 24% de hombres, completaron un número de escalas para comparar los puntajes de ambos grupos (con EFC N = 132 vs sin EFC N = 516. Los resultados mostraron mayor esquizotipia cognitivo-perceptual, absorción, disociación, propensidad a la fantasía, tendencia a alucinar, imaginería visual en individuos que tienen EFC en comparación con un grupo control. La incidencia de tales experiencias incluye a individuos que han señalado los efectos benéficos de lasEFCs como un modo adaptativo al estrés postraumático.ABSTRACTAbstract. An out-of-body experience or OBE is one in which the “self” or center of awareness seems to the experient to occupy temporarily a position that is spatially remote from his or her body. A total of 648 undergraduate students population included 76% females and 24% males, and who completed a number of scales. Data for experients of OBE were compared with data for those who did not (experients N= 132 vs. non‑experients N= 516. The results showed a higher level of cognitive-perceptual schizotypy, absorption, dissociation, fantasy and hallucination proneness, and visual imagery in OBErs than in non-OBErs. This study suggest that the dissociational model of OBE. Anomalous perceptual experiences and some subjects report beneficial effects from OBEs in an adaptive way.

  16. Resección hepática asistida con radiofrecuencia bipolar: primeras experiencias con el Surtron SB

    Directory of Open Access Journals (Sweden)

    José Luis González González

    Full Text Available Las resecciones primarias y secundarias del hígado tienen como uno de sus mayores dilemas el sangrado transoperatorio. La introducción de los equipos de radiofrecuencia, en particular el Surtron SB, comienza a dar resultados alentadores. Se presentan las primeras 8 experiencias cubanas con resecciones menores y mayores realizadas con este equipo. Siete de estos pacientes tenían metástasis y uno un hepatocarcinoma. Se practicaron 2 resecciones regladas y 6 atípicas, durante las cuales no hubo complicaciones y solo un paciente necesitó transfusión sanguínea.

  17. La experiencia vivida de la mujer con enfermedad cardiovascular revascularizada: un estudio de caso

    Directory of Open Access Journals (Sweden)

    Inna Elida Florez Torres

    2016-09-01

    Full Text Available Objetivo: Comprender los significados de la experiencia vivida de una mujer revascularizada por enfermedad coronaria. Metodología: Estudio de caso fenomenológico con perspectiva de género, realizado en Cartagena, Colombia, entre febrero y junio de 2015. El análisis temático estuvo guiado por el método de Van Manen.  Resultados: La experiencia del cuerpo vivido significó percibir el anuncio de la enfermedad, prever los estragos sobre la corporeidad y feminidad, y anticiparse al sufrimiento. Las relaciones vividas significaron mantener un diálogo con un ser superior, una conexión de ayuda y dependencia con los cuidadores, Sentirse “al revés”: de cuidadora a cuidada. La experiencia del espacio vivido significó la entrada al quirófano: Atravesar la raya roja; la estancia en la unidad de cuidado intensivo, recibir un cuidado en soledad; salir de ella, la alegría de ganar una lucha. El tiempo vivido significó un punto de quiebre entre el antes y el ahora, un tránsito temporal de la experiencia, y recuperarse para mantener el rol. Las cosas vividas significaron una preocupación anticipada y una  pérdida del dominio del rol. Conclusión: Los significados otorgados a la experiencia permiten comprender su particularidad existencial. Durante la espera para la cirugía, la mujer se anticipa a los efectos sobre el rol social, sus dinámicas e interacciones; al enfrentarse al procedimiento, vive una situación límite. Intervenciones sensibles al género son requeridas para reconocer las necesidades de la mujer en los diferentes contextos de cuidado.

  18. Automated quantitative coronary computed tomography correlates of myocardial ischaemia on gated myocardial perfusion SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Graaf, Michiel A. de; Boogers, Mark J.; Veltman, Caroline E. [Leiden University Medical Center, Department of Cardiology, Leiden (Netherlands); The Interuniversity Cardiology Institute of The Netherlands, Utrecht (Netherlands); El-Naggar, Heba M.; Bax, Jeroen J.; Delgado, Victoria [Leiden University Medical Center, Department of Cardiology, Leiden (Netherlands); Broersen, Alexander; Kitslaar, Pieter H.; Dijkstra, Jouke [Leiden University Medical Center, Department of Radiology, Division of Image Processing, Leiden (Netherlands); Kroft, Lucia J. [Leiden University Medical Center, Department of Radiology, Leiden (Netherlands); Younis, Imad Al [Leiden University Medical Center, Department of Nuclear Medicine, Leiden (Netherlands); Reiber, Johan H. [Leiden University Medical Center, Department of Radiology, Division of Image Processing, Leiden (Netherlands); Medis medical imaging systems B.V., Leiden (Netherlands); Scholte, Arthur J. [Leiden University Medical Center, Department of Cardiology, Leiden (Netherlands)

    2013-08-15

    Automated software tools have permitted more comprehensive, robust and reproducible quantification of coronary stenosis, plaque burden and plaque location of coronary computed tomography angiography (CTA) data. The association between these quantitative CTA (QCT) parameters and the presence of myocardial ischaemia has not been explored. The aim of the present investigation was to evaluate the association between QCT parameters of coronary artery lesions and the presence of myocardial ischaemia on gated myocardial perfusion single-photon emission CT (SPECT). Included in the study were 40 patients (mean age 58.2 {+-} 10.9 years, 27 men) with known or suspected coronary artery disease (CAD) who had undergone multidetector row CTA and gated myocardial perfusion SPECT within 6 months. From the CTA datasets, vessel-based and lesion-based visual analyses were performed. Consecutively, lesion-based QCT was performed to assess plaque length, plaque burden, percentage lumen area stenosis and remodelling index. Subsequently, the presence of myocardial ischaemia was assessed using the summed difference score (SDS {>=}2) on gated myocardial perfusion SPECT. Myocardial ischaemia was seen in 25 patients (62.5 %) in 37 vascular territories. Quantitatively assessed significant stenosis and quantitatively assessed lesion length were independently associated with myocardial ischaemia (OR 7.72, 95 % CI 2.41-24.7, p < 0.001, and OR 1.07, 95 % CI 1.00-1.45, p = 0.032, respectively) after correcting for clinical variables and visually assessed significant stenosis. The addition of quantitatively assessed significant stenosis ({chi} {sup 2} = 20.7) and lesion length ({chi} {sup 2} = 26.0) to the clinical variables and the visual assessment ({chi} {sup 2} = 5.9) had incremental value in the association with myocardial ischaemia. Coronary lesion length and quantitatively assessed significant stenosis were independently associated with myocardial ischaemia. Both quantitative parameters have

  19. Experiencia en el manejo del paciente con VIH entre médicos de la Secretaría de Salud

    OpenAIRE

    Magis-Rodríguez Carlos; Esquivel-Pedraza Lilly; López-Martínez Carlos

    1999-01-01

    OBJETIVO: Conocer la experiencia que los médicos de la Secretaría de Salud (SSA) han obtenido en el manejo del sujeto infectado por el VIH y en el uso de antirretrovirales. MATERIAL Y MÉTODOS: Se realizó un estudio transversal, con el apoyo del Consejo Nacional para la Prevención y el Control del SIDA (CONASIDA), en marzo-mayo de 1998. Se proporcionaron cuestionarios autoaplicables a médicos de la SSA con experiencia en el manejo clínico del paciente con VIH, al inicio de cinco simposios sobr...

  20. Evaluation of global and regional left ventricular function obtained by quantitative gated SPECT using {sup 99m}Tc-tetrofosmin for left ventricular dysfunction

    Energy Technology Data Exchange (ETDEWEB)

    Ban, Kazunobu; Nakajima, Tohru; Iseki, Harukazu; Abe, Sumihisa; Handa, Shunnosuke; Suzuki, Yutaka [Tokai Univ., Isehara, Kanagawa (Japan). School of Medicine

    2000-08-01

    The quantitative gated SPECT (QGS) software is able to calculate LV volumes and visualize LV wall motion and perfusion throughout the cardiac cycle using an automatic edge detection algorithm of the left ventricle. We evaluated the reliability of global and regional LV function assessment derived from QGS by comparing it with the results from left ventriculo-cineangiography (LVG). In 20 patients with left ventricular dysfunction who underwent ECG gated {sup 99m}Tc-tetrofosmin SPECT, the end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (LVEF) were calculated. The QGS-assessed regional wall motion was determined using the cinematic display. QGS-derived EDV, ESV and LVEF correlated well with those by LVG (p<0.001 for each). There was a good correlation between wall motion score (WMS) derived from the QGS and the LVG (r=0.40, p<0.05). In some patients with extensive myocardial infarction, there was a discrepancy in the regional wall motion results between QGS and LVG. The ECG-gated SPECT using QGS is useful to evaluate global and regional LV functions in left ventricular dysfunction. (author)

  1. Vivir con cáncer: una experiencia de cambios profundos provocados por la quimioterapia

    Directory of Open Access Journals (Sweden)

    Paula Jaman-Mewes

    2014-01-01

    Full Text Available Objetivo: develar las experiencias de mujeres chilenas con cáncer en tratamiento con quimioterapia. Materiales y método: estudio de investigación cualitativa fenomenológica según el pensamiento filosófico de Martín Heidegger. Se entrevistaron en profundidad a 10 mujeres entre 45 y 64 años, con diferentes diagnósticos de cáncer en tratamiento con quimioterapia. El análisis se realizó basado en el método de Streubert y Carpenter, triangulando con un investigador experto. Resultados: la experiencia de vivir con cáncer y con quimio- terapia significa estar “viviendo con un tratamiento que provoca cambios profundos en la vida de las mujeres”, siendo esta una categoría comprensiva esencial del estudio que contiene cuatro unidades de significados: 1 cambios en todas las dimensiones del “ser” de las mujeres tanto a nivel corporal como emocional y espiritual; 2 cambios en el “ser-sí-misma”: antes y durante la quimioterapia; 3 cambios de “ser” en el mundo; 4 cambios en la familia. Conclusiones: la comprensión en profundidad de lo vivido por las mujeres de este estudio confirma lo publicado en la literatura, y se constituye en un saber comprensivo que puede servir de guía para realizar cuidados de enfermería oncológicos humanos y personalizados basados en las necesidades de cada persona.

  2. DIAGNOSTIC VALUE of Tc-99m TETROFOSMİN GATED SPECT IN MYOCARDIAL VIABILITY INVESTIGATION AFTER ADMINISTRATION TRIMETAZIDINE and NITRATE IN THE PATIENTS WITH MYOCARDIAL INFARCTION

    OpenAIRE

    TURHAL, Özgül; TUTUŞ, Ahmet; KULA, Mustafa

    2018-01-01

    ABSTRACT Aim: With the aim of investigating of the myocardial viability on the patients with MI, the results obtained from Tc-99m-tetrofosmin gated SPECT following the nitrate infusion and acute TMZ were compared.Method: For this study, 30 patients who had MI and were be planned of revascularization process were taken. The patients were applied Tc-99m-tetrofosmin gated SPECT basally and following nitrate infusion and acute TMZ separately each day. The data from perfusion were quantitatively e...

  3. Prediction of functional recovery after primary PCI using the estimate of myocardial salvage in gated SPECT early after acute myocardial infarction

    Energy Technology Data Exchange (ETDEWEB)

    Calabretta, Raffaella; Castello, Angelo; Linguanti, Flavia; Tutino, Francesca; Ciaccio, Alfonso; Sciagra, Roberto [University of Florence, Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences ' ' Mario Serio' ' , Florence (Italy); Giglioli, Cristina [Careggi University Hospital, Cardiothoracovascular Department, Florence (Italy)

    2018-04-15

    Primary percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) aims to achieve myocardial salvage (MS). Because the reference method for measuring MS requires myocardial perfusion imaging (MPI) after tracer injection before PCI, alternative approaches have been proposed, but none has gained wide acceptance. Gated SPECT MPI can assess infarct size (IS), but can also show myocardial stunning. Thus, we compared functional and perfusion abnormalities early after AMI to estimate MS, and to predict left ventricular ejection fraction (LVEF) recovery at follow-up. We studied 120 patients with AMI. Gated SPECT MPI was performed early (before hospital discharge) and at 6 months after AMI to measure IS, MS and functional outcome. MS was defined as the difference between the number of segments with abnormal thickening (i.e. the stunned area or area at risk) and the number of segments with abnormal perfusion (i.e. the final IS), expressed as a percentage of the total number of segments in the AHA model. LVEF was calculated using quantitative gated SPECT. The area at risk was 40 ± 25%, IS was 17.3 ± 16% and MS was 22 ± 19%. Early LVEF was 46.6 ± 11.6% and late LVEF was 51.4 ± 11.6%, with 54 patients showing at least an increase in LVEF of more than 5 units. ROC analysis showed that MS was able to predict LVEF recovery with an area under the curve (AUC) of 0.79 (p < 0.0001), and using a cut off >23% detected LVEF recovery with 74% sensitivity and 71% specificity. Conversely, IS was associated with an AUC 0.53 (not significant). MS assessed by a single early gated SPECT MPI study can accurately predict LVEF evolution after primary PCI for AMI. (orig.)

  4. GATED SPECT TO EVALUATE LEFT VENTRICULAR MYOCARDIAL PERFUSION, FUNCTION AND DYSSYNCHRONY FOR RESYNCHRONIZATION THERAPY

    Directory of Open Access Journals (Sweden)

    E.N. Ostroumov

    2009-01-01

    Full Text Available The study included 15 consecutive patients with heart failure and substantial LV dyssynchrony undergoing CRT. Clinical and phase analysis of gated myocardial perfusion SPECT assessed at baseline, after 2–3 days and after 3–4 months of CRT. The results demonstrated inversely relationship between the response to CRT and the nonviable myocardium. Evaluation of myocardial viability is necessary to considered in the selection process for CRT.

  5. The value of regional wall motion abnormalities on 99Tcm-MIBI gated cardiac SPECT in predicting angiographic stenoses of coronary artery

    International Nuclear Information System (INIS)

    Li Dianfu; Huang Jun; Zhu Tiebing; Wang Liansheng; Yang Zhijian; Feng Jianlin; Li Jianhua; Chen Jianwei; Chang Guojun

    2004-01-01

    Objective: To determine the magnitude of angiographic stenoses of coronary artery in reversible regional wall motion abnormalities (RWMA) present in exercise stress 99 Tc m -methoxyisobutylisonitrile (MIBI) gated SPECT myocardial perfusion imaging (MPI). Methods: One hundred and sixteen patients undergoing coronary angiography two weeks before and after the exercise stress 99 Tc m -MIBI gated SPECT MPI. Images were acquired 15 to 20 min after stress. A five grades and twenty segments marking system was introduced to assess the RWMA and thickening of left ventricles. Results: The sensitivity of reversible RWMA for detecting ≥75% angiographic stenoses was 65%, with a specificity of 97%. Reversible RWMA has a high positive predictive value (98%) for stratification between severe angiographic stenoses of 75% and non-severe stenoses (less than 75%). Multivariate analysis showed that the post-stress wall motion (SSSWM), exercise wall motion differentiation value (SDSWM) and summed stress score (SSS) were the independent risk factor of coronary artery jeopardy score. Conclusions: Reversible RWMA, as shown by exercise stress 99 Tc m -MIBI gated SPECT MPI, is a significant predictor of angiographic disease with very high specificity and positive predictive values. Exercise reversible RWMA can rise the assessment value of angiographic severity in MPI

  6. 310. Experiencia inicial con el uso del sistema zipfix de osteosíntesis esternal

    Directory of Open Access Journals (Sweden)

    E. Monguió

    2012-04-01

    Conclusiones: En esta experiencia inicial, no se detectaron problemas de eficacia o seguridad del cierre esternal mediante el sistema ZipFix. Los resultados fueron comparables al cierre convencional con alambres de acero. Es necesario un subsiguiente estudio comparativo.

  7. Prognostic study of risk stratification among Japanese patients with ischemic heart disease using gated myocardial perfusion SPECT: J-ACCESS study

    International Nuclear Information System (INIS)

    Nishimura, Tsunehiko; Nakajima, Kenichi; Kusuoka, Hideo; Yamashina, Akira; Nishimura, Shigeyuki

    2008-01-01

    Although the prognostic value of myocardial perfusion imaging using gated single photon emission computed tomography (SPECT) for predicting major cardiac events has been evaluated, little is known about the relevance of this procedure to the Japanese population. A total of 4,031 consecutive Japanese patients with suspected or confirmed ischemic heart diseases were registered at 117 hospitals in the Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT investigation. Gated stress/rest myocardial perfusion SPECT was performed and the patients were followed up for 3 years. Segmental perfusion scores and quantitative gated SPECT results were calculated. Major cardiac events were defined as cardiac death, nonfatal myocardial infarction, and severe heart failure. During the 3-year follow-up, cardiac death (n = 57) and nonfatal myocardial infarction (n = 39) occurred in 96 patients (2.4%/3 years) when hard events were the endpoints. When severe heart failure was included as an endpoint, major cardiac events that developed in 175 patients (4.3%/3 years) comprised cardiac death (n = 45), nonfatal myocardial infarction (n = 37), and severe heart failure (n = 93). Normal and severely abnormal summed stress score values were associated with low (2.31%/3 years) and high (9.21%/3 years) rates of major cardiac events, respectively. Rates of major cardiac events were significantly higher in patients with ejection fraction (EF) <45% than in those with EF 45% or higher (16.55 vs 2.94%/3 years; P < 0.001). The incidence of major cardiac events within 3 years was also significantly higher among patients with high end-systolic volumes. The major event rates were similar among nondiabetic patients with and diabetic patients without prior myocardial infarction at 5.06% and 5.73%/3 years, respectively. Cardiac event rates were significantly lower in the Japanese than in the USA and European populations. However, large myocardial perfusion defects and

  8. Experiencias y recursos con las tics para la atención al alumnado con necesidades educativas especiales

    Directory of Open Access Journals (Sweden)

    Eladio Sebastian Heredero

    2014-02-01

    Full Text Available Este trabajo tiene como objetivo levantar algunas experiencias llevadas a cabo en centros educativos en los que se ponen de manifiesto buenas prácticas con el uso de las tecnologías para la atención al alumnado con necesidades educativas. Se ha realizado a través de una metodología mixta que alterna el trabajo de investigación de campo con el análisis documental, para finalmente llegar a presentar algunos ejemplos clarificadores y eficaces de prácticas educativas concretas. Los ejemplos aquí aportados, tienen como innovación, que nos presentan prácticas de aula, testadas y aplicadas, y a partir de ellas poder establecer algunas conclusiones e ideas para su mejora.

  9. Respiratory lung motion analysis using a nonlinear motion correction technique for respiratory-gated lung perfusion SPECT images

    International Nuclear Information System (INIS)

    Ue, Hidenori; Haneishi, Hideaki; Iwanaga, Hideyuki; Suga, Kazuyoshi

    2007-01-01

    This study evaluated the respiratory motion of lungs using a nonlinear motion correction technique for respiratory-gated single photon emission computed tomography (SPECT) images. The motion correction technique corrects the respiratory motion of the lungs nonlinearly between two-phase images obtained by respiratory-gated SPECT. The displacement vectors resulting from respiration can be computed at every location of the lungs. Respiratory lung motion analysis is carried out by calculating the mean value of the body axis component of the displacement vector in each of the 12 small regions into which the lungs were divided. In order to enable inter-patient comparison, the 12 mean values were normalized by the length of the lung region along the direction of the body axis. This method was applied to 25 Technetium (Tc)-99m-macroaggregated albumin (MAA) perfusion SPECT images, and motion analysis results were compared with the diagnostic results. It was confirmed that the respiratory lung motion reflects the ventilation function. A statistically significant difference in the amount of the respiratory lung motion was observed between the obstructive pulmonary diseases and other conditions, based on an unpaired Student's t test (P<0.0001). A difference in the motion between normal lungs and lungs with a ventilation obstruction was detected by the proposed method. This method is effective for evaluating obstructive pulmonary diseases such as pulmonary emphysema and diffuse panbronchiolitis. (author)

  10. Benefits of quantitative gated SPECT in evaluation of perioperative cardiac risk in noncardiac surgery

    International Nuclear Information System (INIS)

    Watanabe, Koji; Ohsumi, Yukio; Abe, Hirohiko; Hattori, Masahito; Minatoguchi, Shinya; Fujiwara, Hisayoshi

    2007-01-01

    Gated single-photon emission computed tomography (G-SPECT) was used to evaluate cardiac risk associated with noncardiac surgery and determine the benefits and indications of this technique for this type of surgery. Patients scheduled to undergo noncardiac surgery under the supervision of anesthesiologists and subjected to preoperative cardiac evaluation using G-SPECT during the 26-month period between June 2000 and August 2002 were followed for the presence/absence of cardiac events (id est (i.e.), cardiac death, myocardial infarction, unstable angina, congestive heart failure, or fatal arrhythmia) during surgery and the postoperative period until discharged. Relationships between the occurrence of cardiac events and preoperative G-SPECT findings were evaluated. A total of 39 patients underwent G-SPECT; 6 of the 39 exhibited abnormal ejection fraction (left ventricular ejection fraction, left ventricular ejection fraction (LVEF)≤50%) and end-systolic volume (end-systolic volume (ESV)≥50 ml). Surgery was suspended for three of these six patients and cardiac events developed in the remaining three patients. Both abnormal perfusion images (PI) and abnormal wall thickening (WT) were observed in all six patients. All six patients exhibited abnormal LVEF and/or ESV. Three patients had either abnormal PI or WT, and a cardiac event occurred in one of them. Of the five patients who experienced cardiac events during or after surgery, two exhibited a short run of ventricular tachycardia requiring a continuous administering of antiarrhythmic drugs, whereas the remaining three patients exhibited cardiac failure requiring inotropic support following surgery. The results of this study indicate that the occurrence of perioperative cardiac events can be predicted by considering the severity of expected surgical stress and preoperative G-SPECT findings for LVEF, PI, and WT. We conclude that G-SPECT is quite useful for cardiac risk assessment in patients undergoing noncardiac

  11. Enseñar a aprender con TIC: una experiencia en el marco de un profesorado universitario

    OpenAIRE

    Martín, María Victoria; Vestfrid, Pamela

    2015-01-01

    Se presenta la experiencia llevada adelante en el “Taller Estrategias de trabajo colaborativo para el aula con redes sociales virtuales y otros asistentes online”, optativo para el Profesorado en Comunicación Social de la Facultad de Periodismo y Comunicación Social, UNLP. La misma busca brindar saberes conceptuales pero, fundamentalmente vivenciar experiencias de trabajo colaborativo que impliquen cambios en la esencia de los procesos educativos, modificando las verticales y desiguales relac...

  12. Reproducibility of an automatic quantitation of regional myocardial wall motion and systolic thickening on gated Tc-99m-MIBI myocardial SPECT

    International Nuclear Information System (INIS)

    Paeng, Jin Chul; Lee, Dong Soo; Cheon, Gi Jeong; Kim, Yu Kyeong; Chung, June Key; Lee, Myung Chul

    2000-01-01

    The aim of this study is to investigate the reproducibility of the quantitative assessment of segmental wall motion and systolic thickening provided by an automatic quantitation algorithm. Tc-99m-MIBI gated myocardial SPECT with dipyridamole stress was performed in 31 patients with known or suspected coronary artery disease (4 with single, 6 with two, 11 with triple vessel disease; ejection fraction 51±14%) twice consecutively in the same position. Myocardium was divided into 20 segments. Segmental wall motion and systolic thickening were calculated and expressed in mm and % increase respectively, using AutoQUANT TM software. The reproducibility of this quantitative measurement of wall motion and thickening was tested. Correlations between repeated measurements on consecutive gated SPECT were excellent for wall motion (r=0.95) and systolic thickening (r=0.88). On Bland-Altman analysis, two standard deviation was 2 mm for repeated measurement of segmental wall motion, and 20% for that of systolic thickening. The weighted kappa values of repeated measurements were 0.807 for wall motion and 0.708 for systolic thickening. Sex, perfusion, or segmental location had no influence on reproducibility. Segmental wall motion and systolic thickening quantified using AutoQUANT TM software on gated myocardial SPECT offers good reproducibility and is significantly different when the change is more than 2 mm for wall motion and more than 20% for systolic thickening

  13. La experiencia de ser cuidadora de un anciano con enfermedad crónica

    Directory of Open Access Journals (Sweden)

    Gabriela Aldana-González

    2011-01-01

    Full Text Available Objetivo: conocer la construcción de la experiencia de ser cuidador de un anciano con enfermedad crónico-degenerativa en mujeres de San Cristóbal Ecatepec, México. Método: investigación de corte cualitativo, con cuatro personas de sexo femenino todas ellas cuidadoras de ancianos con enfermedades crónico-degenerativas. Se utilizó la entrevista a profundidad como técnica para la recolección de datos. Los datos se analizaron a partir de ubicar categorías de análisis desde una orientación fenomenológica. La investigación se llevó a cabo en la ciudad de San Cristóbal Ecatepec, Estado de México, México, entre marzo y junio del 2008. Resultados: el rol de cuidador está asignado a las mujeres. La categoría que aquí se describe se refiere a la cotidianidad del cuidado. Los discursos nos permiten develar el conflicto al que se enfrentan las cuidadoras: la responsabilidad moral del cuidado al adulto mayor y la necesidad de desarrollar un proyecto de vida autónomo. Conclusiones: la experiencia de ser cuidadora se asume como una responsabilidad y un compromiso moral que tiene que cumplirse por encima del cuidado personal. Tiene relación con la cultura mexicana respecto a la construcción de género y familia.

  14. Development of 4D mathematical observer models for the task-based evaluation of gated myocardial perfusion SPECT

    Science.gov (United States)

    Lee, Taek-Soo; Frey, Eric C.; Tsui, Benjamin M. W.

    2015-04-01

    This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical observer model extends the conventional channelized Hotelling observer (CHO) based on a set of 2D spatial channels and the second is a proposed model that uses a set of 4D space-time channels. Simulated projection data were generated using the 4D NURBS-based cardiac-torso (NCAT) phantom with 16 gates/cardiac cycle. The activity distribution modelled uptake of 99mTc MIBI with normal perfusion and a regional wall motion defect. An analytical projector was used in the simulation and the filtered backprojection (FBP) algorithm was used in image reconstruction followed by spatial and temporal low-pass filtering with various cut-off frequencies. Then, we extracted 2D image slices from each time frame and reorganized them into a set of cine images. For the first model, we applied 2D spatial channels to the cine images and generated a set of feature vectors that were stacked for the images from different slices of the heart. The process was repeated for each of the 1,024 noise realizations, and CHO and receiver operating characteristics (ROC) analysis methodologies were applied to the ensemble of the feature vectors to compute areas under the ROC curves (AUCs). For the second model, a set of 4D space-time channels was developed and applied to the sets of cine images to produce space-time feature vectors to which the CHO methodology was applied. The AUC values of the second model showed better agreement (Spearman’s rank correlation (SRC) coefficient = 0.8) to human observer results than those from the first model (SRC coefficient = 0.4). The agreement with human observers indicates the proposed 4D mathematical observer model provides a good predictor of the

  15. Development of 4D mathematical observer models for the task-based evaluation of gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Lee, Taek-Soo; Frey, Eric C; Tsui, Benjamin M W

    2015-01-01

    This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical observer model extends the conventional channelized Hotelling observer (CHO) based on a set of 2D spatial channels and the second is a proposed model that uses a set of 4D space-time channels. Simulated projection data were generated using the 4D NURBS-based cardiac-torso (NCAT) phantom with 16 gates/cardiac cycle. The activity distribution modelled uptake of 99m Tc MIBI with normal perfusion and a regional wall motion defect. An analytical projector was used in the simulation and the filtered backprojection (FBP) algorithm was used in image reconstruction followed by spatial and temporal low-pass filtering with various cut-off frequencies. Then, we extracted 2D image slices from each time frame and reorganized them into a set of cine images. For the first model, we applied 2D spatial channels to the cine images and generated a set of feature vectors that were stacked for the images from different slices of the heart. The process was repeated for each of the 1,024 noise realizations, and CHO and receiver operating characteristics (ROC) analysis methodologies were applied to the ensemble of the feature vectors to compute areas under the ROC curves (AUCs). For the second model, a set of 4D space-time channels was developed and applied to the sets of cine images to produce space-time feature vectors to which the CHO methodology was applied. The AUC values of the second model showed better agreement (Spearman’s rank correlation (SRC) coefficient = 0.8) to human observer results than those from the first model (SRC coefficient = 0.4). The agreement with human observers indicates the proposed 4D mathematical observer model provides a good predictor of the

  16. Prognostic Value of Normal Perfusion but Impaired Left Ventricular Function in the Diabetic Heart on Quantitative Gated Myocardial Perfusion SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Hwanjeong; Choi, Sehun; Han, Yeonhee [Research Institute of Chonbuk National Univ. Medical School and Hospitial, Jeonju (Korea, Republic of); Lee, Dong Soo; Lee, Hoyoung; Chung, Junekey [Seoul National Univ., Seoul (Korea, Republic of)

    2013-09-15

    This study aimed at identifying the predictive parameters on quantitative gated myocardial perfusion single-photon emission computed tomography (QG-SPECT) in diabetic patients with normal perfusion but impaired function. Methods Among the 533 consecutive diabetic patients, 379 patients with normal perfusion on rest Tl-201/dipyridamole-stress Tc-{sup 99m} sestamibi Gated SPECT were enrolled. Patients were grouped into those with normal post-stress left ventricular function (Group I) and those with impaired function (EF <50 or impaired regional wall motion, Group II). We investigated cardiac events and cause of death by chart review and telephone interview. Survival analysis and Cox proportional hazard model analysis were performed. Between the Group I and II, cardiac events as well as chest pain symptoms, smoking, diabetic complications were significantly different (P<0.05). On survival analysis, event free survival rate in Group II was significantly lower than in Group I (P=0.016). In univariate Cox proportional hazard analysis on overall cardiac event, Group (II over I), diabetic nephropathy, summed motion score (SMS), summed systolic thickening score (STS), numbers of abnormal segmental wall motion and systolic thickening predicted more cardiac events (P<0.05). Multivariate analysis showed that STS was the only independent predictor cardiac event. The functional parameter, especially summed systolic thickening score on QG-SPECT had prognostic values, despite normal perfusion, in predicting cardiac events in diabetic patients, and QG-SPECT provides clinically useful risk stratification in diabetic patients with normal perfusion.

  17. Experiencia con Nexobrid® para el desbridamiento enzimático de quemaduras faciales seguido de tratamiento conservador con Medihoney®

    Directory of Open Access Journals (Sweden)

    José-Manuel Sampietro-De-Luis

    Full Text Available Introducción y Objetivos. El desbridamiento enzimático de las quemaduras ha sido objeto de estudio durante décadas; en este terreno, NexoBrid® (MediWound Ltd., Israel se postula como una prometedora alternativa al desbridamiento quirúrgico clásico. Por otra parte, las propiedades antibacterianas y promotoras de la cicatrización de la miel también se han evaluado recientemente con buenos resultados clínicos. Describimos nuestra experiencia preliminar con el empleo de NexoBrid® para el tratamiento de quemaduras faciales, seguido de curas tópicas con Medihoney® Wound Gel (Derma Sciences Ltd., EE.UU.. Material y Método. Incluimos en el estudio todos los pacientes atendidos en nuestra Unidad de Quemados con quemaduras faciales dérmicas o subdérmicas que afectaban a 2 o más subunidades estéticas. Realizamos desbridamiento enzimático con NexoBrid® en las primeras 24 horas. Posteriormente, llevamos a cabo tratamiento conservador con curas tópicas con Medihoney® Wound Gel. Recogimos todos los datos de calidad del desbridamiento, necesidad de desbridamiento quirúrgico, tiempo hasta epitelización completa, presencia de infección y necesidad de cirugía correctora de secuelas. Resultados. Tratamos 10 pacientes con quemaduras faciales de etiología diversa (llama, flash eléctrico, deflagración, escaldadura y química. El desbridamiento inicial fue completo en todos los pacientes. Se alcanzó la epitelización completa en una media de 13.88 días (10-20 días. Ningún paciente presentó infección clínicamente manifiesta ni precisó desbridamiento quirúrgico, cobertura mediante autoinjertos o cirugía de secuelas. Conclusiones. Nuestra experiencia preliminar indica que parece factible la aplicación de NexoBrid® y su combinación con Medihoney® para el tratamiento conservador de las quemaduras faciales.

  18. SPECT acquisition using dynamic projections: a novel approach for data-driven respiratory gating

    International Nuclear Information System (INIS)

    Hutton, B.F.; Hatton, R.L.; Yip, N.

    2002-01-01

    Full text: Movement of the heart due to respiration has been previously demonstrated to produce potentially serious artefacts. On-line respiratory gating is difficult, as it requires a high level of patient cooperation. We demonstrate that use of dynamic acquisition of projections permits identification of the respiratory dynamics, allowing retrospective selection of data corresponding to a fixed point in the respiratory cycle. To demonstrate the feasibility of the technique a dynamic study was acquired just prior to myocardial per-fusion SPECT acquisition, using 5 frames/sec for 20 seconds (64*64 matrix) in anterior and lateral projections (using a dual-head right-angled configuration). The dynamic was processed a) by compressing frames in the transverse direction so as to illustrate time dependence, b) by plotting the centre of mass in the axial direction as a function of time. Respiratory motion was enhanced by use of temporal smoothing and intensity thresholding. In ten patients studied the cyclic pattern of motion due to respiratory dynamics was clearly visible in nine. Respiration typically resulted in around 1cm axial translation but in some individuals, movements as large as 3 cm were identified. The respiration rate ranged from 12-18 /min in agreement with independent observation of the patient's breathing pattern. These results suggest that retrospective respiratory gating is feasible without the need for any external respiratory monitoring device, provide that dynamic acquisition of SPECT projections is implemented. Correction for respiratory motion may also be feasible using this technique. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  19. Limited diagnostic accuracy of gated myocardial perfusion SPECT for wall motion analysis in patients with asymmetric septal hypertrophy

    International Nuclear Information System (INIS)

    Seo, J.H.; Ahn, B.C.; Bae, J.H.; Jeong, S.Y.; Lee, J.; Lee, K.B.

    2004-01-01

    Objective: Although gated SPECT(G-SPECT) using Tc-99m MIBI is well-known diagnostic modality in the evaluation of myocardial perfusion and wall motion analysis, there were limited reports for subjects with asymmetric septal hypertrophy (ASH). This study was performed to evaluate the clinical usefulness of G-SPECT for assessments of myocardial perfusion and wall motion analysis in patients with ASH on 2D-echocardiography(Echo). Methods: Thirty patients (male 18, 59 12 years) with ASH on Echo (septal wall thickness 13 mm and 1.3 times as thick as that of posterior wall) underwent Tc-99m MIBI G-SPECT. Two studies were performed within one month. No patient had experienced any significant cardiac event, nor had changed medical and surgical therapy during the studies. Functional parameters of the left ventricle were acquired with QGS software(AutoQUANTTM). Three experts performed visual interpretation for the presence of septal thickening and perfusion abnormalities on G-SPECT and two experienced cardiologists measured dimension, thickness and wall motion of the left ventricle on Echo. Results: Mean septum thickness measured by Echo was 1.90 0.50 cm, and the septum/posterior wall thickness ratio was 1.85 0.51. On visual SPECT analysis, 14 patients (46.7%) were interpreted as with thickened septum and 17 patients (57%) as with abnormal perfusion. All 3 patients who underwent coronary angiography showed significant luminal stenosis and also had perfusion abnormalities on SPECT. On Echo, only one patient showed septal hypokinesia, who showed anteroseptal infarction on SPECT, and the others showed normal septal wall motion. But 13 patients (54%) among 24 patients showed septal hypokinesia on G-SPECT. Patients with thickened septum on SPECT had thicker septum (2.3 vs 1.6 cm) and higher septum/posterior wall thickness ratio (2.2 vs 1.6) on Echo, compared with patients without septal thickening on SPECT. Conclusions: Although G-SPECT could proffer diagnostic accuracy for

  20. Experiencia con el colgajo de Kirschbaum en secuelas de quemaduras cérvico-faciales

    Directory of Open Access Journals (Sweden)

    P. Rossell-Perry

    2014-06-01

    Full Text Available Presentamos nuestra experiencia con el colgajo de Kirschbaum (colgajo en charretera en la corrección de retracciones cicatriciales de la región cervical anterior y del tercio inferior de la cara. Llevamos a cabo un estudio retrospectivo sobre una serie de 63 pacientes con retracciones cicatriciales de la región cervical anterior y del tercio inferior facial, operados por el primer autor entre los años 1996 y 2012 dentro del marco de las campañas quirúrgicas desarrolladas a lo largo del país (Perú en las áreas geográficas con mayor necesidad de atención especializada. En todos los casos empleamos el colgajo en charretera tomado de la región lateral del cuello y de la región deltoidea. Evaluamos a los pacientes mediante el examen físico y la documentación fotográfica obtenida en los periodos pre y postoperatorio. Obtuvimos mejoría en diferentes grados de la limitación funcional de la región cervical y facial en todos los casos operados, con viabilidad total del colgajo en 59 casos (93,65 % y parcial en 4 casos (6,34 % . No hubo ningún caso de pérdida total. Las complicaciones recogidas fueron pocas, principalmente hematomas, 6 casos (9,52 % e infección, 2 casos (3,17 % . Las zonas donantes evolucionaron con cicatriz hipertrófica en 22 de los casos (34,92 % . En conclusión, nuestra experiencia con el uso de esta técnica quirúrgica ha demostrado ser de utilidad en el tratamiento de las secuelas de quemadura con retracción cicatricial cervical y facial, por lo que consideramos que el colgajo de Kirschbaum es seguro y tiene pocas complicaciones.

  1. John Dewey: la experiencia estética como experiencia educativa

    Directory of Open Access Journals (Sweden)

    Diana Melisa Paredes Oviedo

    2010-02-01

    Full Text Available La experiencia estética se constituye en un elemento crucial para la obra de John Dewey. En primer lugar, este pensador recupera la idea de experiencia, en sentido amplio, referida a los procesos conscientes realizados por el ser humano. En segundo lugar, esta experiencia aparece como resultado de la interacción de los hombres con su entorno, de tal modo que se amplían las valoraciones que aquellos tienen acerca de éste. En tercer lugar, la experiencia tiene elementos analíticos y sintéticos que posibilitan cualificar los procesos cognitivos y cognoscitivos de los individuos. En cuarto lugar, la experiencia se clasifica de acuerdo a su función en intelectual, práctica y estética, siendo la última la más importante, en tanto que, se muestra como más universal y ampliada frente a las otras, y se comporta como experiencia educativa al ser la que cualifica de manera más profunda los juicios críticos que se hacen frente al mundo.Los anteriores aspectos serán trabajados en este artículo, con miras a explorar la universalidad de la experiencia estética deweyana y sus derivaciones en el campo de una propuesta educativa, en la que resulta de vital importancia la existencia de una experiencia común entre los diferentes grupos humanos para lograr configurar la inteligencia común que es la base para la educación en John Dewey.

  2. Comparison of left ventricular ejection fraction by 201Tl gated SPECT and gated blood pool scan

    International Nuclear Information System (INIS)

    Lau, W.F.E.; Kelly, M.J.; O'Donnell, M.; Kalff, V.; Van Every, B.

    2000-01-01

    Full text: The aim of this study was to evaluate left ventricular ejection fraction (LVEF) determination by the Germano 201 Tl gated-SPECT myocardial perfusion (TLGSMP) method using gated blood pool scintigraphy (GBPS) as a reference. 21 patients underwent both TLGSMP and GBPS within eight days of each other from June 1997 to Jan 2000. Acquisition of TLGSMP was performed on a GE Optima NX dual head camera using Tl-201 dose of 1.5MBq/Kg and imaging time of 45 cardiac cycles/step with 16 steps/90 Deg of rotation per detector. All LVEF results were determined using a GE Genie workstation. GBPS results were compared with TLGSMP results for LVEF obtained from the reinjection images using automated Germano processing, and from the stress images using automatic and manual processing. Duplicate automatic analysis by a second observer produced identical mean TLGSMP LVEF results (r = 0.99). Stress TLGSMP LVEF by the automatic and manual processing correlate well (r = 0.99) but the manual LVEF is significantly lower. In conclusion LVEF determination using TLGSMP is highly reproducible and is also accurate when applied to reinjection data. Both manual processing and the use of stress data lead to underestimation of LVEF. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

  3. Effect of streptozotocin-induced diabetes on left ventricular function in adult rats: an in vivo Pinhole Gated SPECT study

    Directory of Open Access Journals (Sweden)

    Weytjens Caroline

    2007-10-01

    Full Text Available Abstract Background Recent studies have suggested that diabetes mellitus (DM may cause left ventricular (LV dysfunction directly resulting in increased susceptibility to heart failure. Using pinhole collimators and advances in data processing, gated SPECT was recently adapted to image the rat heart. The present study was aimed to assess this new imaging technique for quantifying LV function and remodeling from the Streptozotocin (STZ rat model compared to controls. Methods Twenty one rats were randomly assigned to control or diabetic group. Six months after the induction of diabetes by STZ, Pinhole 99 m Tc-sestamibi gated SPECT was performed for determining rat LV volumes and function. Post-mortem histopathologic analysis was performed to evaluate the determinant of LV remodeling in this model. Results After six months, the normalized to body weight LV End-systolic volume was significantly different in diabetic rats compared to controls (0.46 ± 0.02 vs 0.33 ± 0.03 μL/g; p = 0.01. The normalized LV End-diastolic volume was also different in both groups (1.51 ± 0.03 vs 0.88 ± 0.05 μL/g; p = 0.001 and the normalized stroke volume was significantly higher in STZ-rats (1.05 ± 0.02 vs 0.54 ± 0.06 μL/g; p = 0.001. The muscular fibers were thinner at histology in the diabetic rats (0.44 ± 0.07 vs 0.32 ± 0.06 AU; p = 0.01. Conclusion Pinhole 99 m Tc-sestamibi gated SPECT can successfully be applied for the evaluation of cardiac function and remodeling in STZ-induced diabetic rats. In this model, LV volumes were significantly changed compared to a control population, leading to a LV dysfunction. These findings were consistent with the histopathological abnormalities. Finally, these data further suggest the presence of diabetes cardiomyopathy.

  4. Disfruto el poder de ser feliz: experiencia en personas que viven con VIH

    Directory of Open Access Journals (Sweden)

    Guadalupe Erendira Montoya Ramirez

    2016-12-01

    Full Text Available Las personas que viven con virus de inmunodeficiencia humana (VIH pueden presentar alteraciones biopsicosociales que generan infelicidad. La gaudibilidad (capacidad para ser feliz y disfrutar, puede favorecerse al crear nuevos patrones de conducta mental con la programación neurolingüística (PNL. El propósito fue: analizar la experiencia vivida en un taller de PNL para personas que viven con VIH, a la luz del referente teórico de; Rogers. Estudio cualitativo con diseño fenomenológico, participaron 12 personas de la Asociación CONVIHVE A.C. Michoacán, en un taller de PNL conformado por ocho sesiones. Tratamiento de datos por análisis de contenido, emergieron cinco dimensiones dejando ver el poder de cambio que tienen dichas personas para disfrutar la vida, al generar emociones positivas que se anclaron al inconsciente. Conclusiones. La PNL como intervención de enfermería favorece la gaudibilidad de las personas que viven con VIH.

  5. Feasibility of one-eighth time gated myocardial perfusion SPECT functional imaging using IQ-SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Caobelli, Federico; Thackeray, James T.; Bengel, Frank M. [Medizinische Hochschule Hannover, Klinik fuer Nuklearmedizin, Hannover (Germany); Soffientini, Alberto; Pizzocaro, Claudio; Guerra, Ugo Paolo [Fondazione Poliambulanza, Department of Nuclear Medicine, Brescia (Italy)

    2015-11-15

    IQ-SPECT, an add-on to general purpose cameras based on multifocal collimation, can reduce myocardial perfusion imaging (MPI) acquisition times to one-fourth that of standard procedures (to 12 s/view). In a phantom study, a reduction of the acquisition time to one-eighth of the standard time (to 6 s/view) was demonstrated as feasible. It remains unclear whether such a reduction could be extended to clinical practice. Fifty patients with suspected or diagnosed CAD underwent a 2-day stress-rest {sup 99m}Tc-sestamibi MPI protocol. Two consecutive SPECT acquisitions (6 and 12 s/view) were performed. Electrocardiogram-gated images were reconstructed with and without attenuation correction (AC). Polar maps were generated and visually scored by two blinded observers for image quality and perfusion in 17 segments. Global and regional summed stress score (SSS), summed rest score (SRS) and summed difference score (SDS) were determined. Left ventricular volumes and ejection fraction were calculated based on automated contour detection. Image quality was scored higher with the 12 s/view acquisition, both with and without AC. Summed scores were statistically comparable between the 6 s/view and the 12 s/view acquisition, both globally and in individual coronary territories (e.g. in images with AC, SSS were 6.6 ± 8.3 and 6.2 ± 8.2 with 6 s and 12 s/view, respectively, p = 0.10; SRS were 3.9 ± 5.6 and 3.5 ± 5.3, respectively, p = 0.19; and SDS were 2.8 ± 5.7 and 2.6 ± 5.7, respectively, p = 0.59). Both acquisitions allowed MPI-based diagnosis of CAD in 25 of the 50 patients (with AC). Calculated end-diastolic volume (EDV) and end-systolic volume (ESV) were modestly higher with the 6 s/view acquisition than with the 12 s/view acquisition (EDV +4.8 ml at rest and +3.7 ml after stress, p = 0.003; ESV +4.1 ml at rest and +2.6 ml after stress, p = 0.01), whereas the ejection fraction did not differ (-1.2 % at rest, p = 0.20, and -0.9 % after stress, p = 0.27). Image quality and

  6. Assessment of left ventricular function by gated myocardial perfusion and gated blood-pool SPECT. Can we use the same reference database?

    Energy Technology Data Exchange (ETDEWEB)

    Paul, A.K.; Hasegawa, Shinji; Yoshioka, Jun; Yamaguchi, Hitoshi; Tsujimura, Eiichiro; Nishimura, Tsunehiko [Osaka Univ., Suita (Japan). Graduate School of Medicine

    2000-04-01

    The purpose of this study was to compare left ventricular (LV) volume and ejection fraction (LVEF) measurements obtained with electrocardiographic gated single-photon emission computed tomographic (SPECT) myocardial perfusion imaging (GS-MPI) with those obtained with gated SPECT cardiac blood-pool imaging (GS-pool). Fifteen patients underwent GS-MPI with technetium-99m tetrofosmin and GS-pool with technetium-99m-erythrocyte, within a mean interval of 8{+-}3 days. Eight patients had suspected dilated cardiomyopathy and seven patients had angiographically significant coronary artery disease. End-diastolic volume (EDV), end-systolic volume (ESV) and LVEF measurements were estimated from GS-MPI images by means of Cedars-Sinai automatic quantitative program and from GS-pool images by the threshold technique. Mean differences between GS-MPI and GS-pool in EDV, ESV and LVEF measurements were -2.8{+-}10.5 ml [95% confidence interval (CI): -8.6{+-}3.0 ml], 2.6{+-}7.3 ml (CI: -1.4-6.6 ml) and -2.3{+-}5.1% (CI: -5.1-0.6%), respectively. No significant difference in the mean differences from 0 was found for EDV, ESV or LVEF measurements. Bland-Altman plots revealed no trend over the measured LV volumes and LVEF. For all parameters, regression lines approximated lines of identity. The excellent agreement between GS-MPI and GS-pool measurements suggests that, for estimation of LV volumes and LVEF, these two techniques may be used interchangeably and measurements by one method can serve as a reference for the other. (author)

  7. Experiencia en el manejo del paciente con VIH entre médicos de la Secretaría de Salud

    Directory of Open Access Journals (Sweden)

    Magis-Rodríguez Carlos

    1999-01-01

    Full Text Available OBJETIVO: Conocer la experiencia que los médicos de la Secretaría de Salud (SSA han obtenido en el manejo del sujeto infectado por el VIH y en el uso de antirretrovirales. MATERIAL Y MÉTODOS: Se realizó un estudio transversal, con el apoyo del Consejo Nacional para la Prevención y el Control del SIDA (CONASIDA, en marzo-mayo de 1998. Se proporcionaron cuestionarios autoaplicables a médicos de la SSA con experiencia en el manejo clínico del paciente con VIH, al inicio de cinco simposios sobre VIH/SIDA, realizados en diversas ciudades del país. El análisis estadístico incluyó la prueba ji². RESULTADOS: Se recolectaron 181 encuestas. La mediana de pacientes con VIH atendidos fue de cuatro (intervalo 1-97. De los médicos encuestados, 36.5% manifestó administrar antirretrovirales (35.4% prescribía los análogos de los nucleósidos, y 9.9%, los inhibidores de proteasa. Los fármacos más usados fueron AZT y ddI (40.3%. Expresó 17.7% de los médicos haber utilizado la cuenta de linfocitos T CD4+, y 8.8% la carga viral como indicadores pronósticos y de respuesta a la farmacoterapia. CONCLUSIONES: Se observó una baja proporción de médicos de la SSA con experiencia en el manejo del paciente con VIH y en el uso de los antirretrovirales. Se deben enfocar esfuerzos para mejorar la atención de los pacientes VIH positivos mediante la capacitación del personal médico.

  8. Prediction of improvement of myocardial wall motion after coronary artery bypass surgery using rest Tl-201/dipyridamole stress gated Tc-99m-MIBI/24 hour delay Tl-201 SPECT

    International Nuclear Information System (INIS)

    Lee, Dong Soo; Lee, Won Woo; Yeo, Jeong Yeo; Kim, Seok Ki; Kim, Ki Bong; Chung, June Key; Lee, Myung Chul

    1998-01-01

    Using rest Tl-201/ dipyridamole stress gated Tc-99m-MIBI/24 hour delay Tl-201 SPECT, we investigated the predictive values of the markers of the stress-rest reversibility (Rev), Tl-201 rest perfusion (Rest), Tl-201 24 hour redistribution (Del) and Tc-99m-MIBI gated systolic thickening (Thk) for wall motion improvement after coronary artery bypass surgery. In 39 patients (M:F=34:5, age 58±8), preoperative and postoperative (3 months) SPECT were compared. 24 hour delayed SPECT was done in 16 patients having perfusion defects at rest. Perfusion or wall motion was scored from 0 to 3 (0: normal to 3: defect or dyskinesia). Wall motion was abnormal in 142 segments among 585 segments of 99 artery territories which were surgically revascularized. After bypass surgery, ejection fraction increased from 37.8±9.0% to 45.5±12.3% in 22 patients who had decreased ejectin fraction preoperatively. Wall motion improved in 103 (72.5%) segments among 142 dysfunctional segments. Positive predictive values (PPV) of Rev, Rest, Del, and Thk were 83%, 76%, 43%, and 69% respectively. Negative predictive values (NPV) of Rev, Rest, Del, and Thk were 48%, 44%, 58%, and 21%, respectively. Rest/gated stress/delay SPECT had PPV of 74% and NPV of 46%. Through univariate logistic regression analysis revealed Rev( p=0.0008) and Rest (p=0.024) as significant predictors, stepwise multivariate test found Rev as the only good predictor (p=0.0008). Among independent predictors obtained by rest Tl-201/stress gated Tc-99m-MIBI/delayed Tl-201 myocardial SPECT for wall motion improvement after bypass surgery, stress-rest reversibility was the single most useful predictor

  9. Myocardial perfusion SPECT for assessment of left ventricular function and volume- comparison with echocardiography

    International Nuclear Information System (INIS)

    Cheng Xu; Huang Gang

    2004-01-01

    Objective: The purpose of this study was to evaluate left ventricular volume and function by gated SPECT and comparison of the results with echocardiography. Methods: 65 Consecutive patients (49 male, 16 female; mean age 61+11 years) who underwent both gated 99m Tc-MIBI myocardial perfusion SPECT and echocardiography within a 15 days period were included in the study. Exclusion criteria were any change in clinical status between acquisition of the gated SPECT and echocardiography studies, acute myocardial infarction occurring less than 7 days before study, and surgical procedures occurring within 30 days of the study. The clinical diagnosis of each patient was not considered, as this was not relevant to the purpose of the study. The diagnoses were as follows: coronary artery disease (n=46), hypertensive heart disease (n=8), old myocardial infarction (n=5), myocarditis (n=2), and routine medical examination(n=4). A dose of 740 MBq of 99 Tc m -sestamibi was administered in resting condition. Gated SPECT images were obtained with ADAC Vertex MCD-AC SPECT system. The raw projection images were reconstructed with filtered back-projection (ramp filter), without attenuation correction. The data, including left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), end-systolic volume (ESV) were obtained using AUTOQUANT software (ADAC corporation). The echocardiography study used its standard techniques. Two nuclear medicine physicians processed the raw images respectively to evaluate internal reproducibility of gated SPECT. In order to compare the results of gated SPECT with echocardiography on different left ventricular volumes, all patients were divided into two groups (EDV 90 ml, n=34) based by EDV measurements in echocardiography. Results: The correlation coefficient of LVEF, EDV, ESV between SPECT and echocardiography were 0.77, 0.86 and 0.90 respectively. P 0.07). The reproducibility of gated SPECT was excellent. There were no significant differences in

  10. SPECT Myocardial Blood Flow Quantitation Concludes Equivocal Myocardial Perfusion SPECT Studies to Increase Diagnostic Benefits.

    Science.gov (United States)

    Chen, Lung-Ching; Lin, Chih-Yuan; Chen, Ing-Jou; Ku, Chi-Tai; Chen, Yen-Kung; Hsu, Bailing

    2016-01-01

    Recently, myocardial blood flow quantitation with dynamic SPECT/CT has been reported to enhance the detection of coronary artery disease in human. This advance has created important clinical applications to coronary artery disease diagnosis and management for areas where myocardial perfusion PET tracers are not available. We present 2 clinical cases that undergone a combined test of 1-day rest/dipyridamole-stress dynamic SPECT and ECG-gated myocardial perfusion SPECT scans using an integrated imaging protocol and demonstrate that flow parameters are capable to conclude equivocal myocardial perfusion SPECT studies, therefore increasing diagnostic benefits to add value in making clinical decisions.

  11. Comparison of myocardial function between post-menopausal and pre-menopausal women: evaluation by gated myocardial SPECT

    International Nuclear Information System (INIS)

    Hwang, K. H.; Choa, Won Sick; Yoon, Min Ki

    2005-01-01

    In addition to inhibiting coronary atherosclerosis, estrogen is expected to have protective effects on cardiac myocytes. We investigated the difference in myocardial functional parameters evaluated by gated myocardial SPECT after adenosine-stress between post-menopausal and pre-menopausal healthy women. This study included 22 healthy post-menopausal women (mean age: 53.0 yr) and 20 pre-menopausal women (mean age: 43.0 yr) who performed Tc-99m tetrofosmin gated myocardial SPECT after adenosine-stress. Measured hemodynamic parameters, EDV, ESV, stroke volume, EF, cardiac output and cardiac index were compared between the two groups. For comparison, similar-aged two male groups with matched numbers were also studied. There was no significant difference in hemodynamic parameters. EDV, ESV, stroke volume, EF, or cardiac output between the post-menopausal and pre-menopausal women. However, post-menopausal women have a smaller cardiac index (mean: 1.95 L/min/m2 vs 2.20 L/min/m2; p=0.045) and adenosine-induced HR increase (mean : 80.5/min vs 89.7/min ; p=0.03), compared to the pre-menopausal women. On the contrary, the two male groups of the same age range and numbers with the women groups showed no significant difference in any myocardial parameters. These results suggest that menopause may be correlated with reduced increase in cardiac index and HR increase after adenosine-stress

  12. Comparison of myocardial function between post-menopausal and pre-menopausal women: evaluation by gated myocardial SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, K. H.; Choa, Won Sick; Yoon, Min Ki [Gachon Medical School, Gil Hospital, Incheon (Korea, Republic of)

    2005-07-01

    In addition to inhibiting coronary atherosclerosis, estrogen is expected to have protective effects on cardiac myocytes. We investigated the difference in myocardial functional parameters evaluated by gated myocardial SPECT after adenosine-stress between post-menopausal and pre-menopausal healthy women. This study included 22 healthy post-menopausal women (mean age: 53.0 yr) and 20 pre-menopausal women (mean age: 43.0 yr) who performed Tc-99m tetrofosmin gated myocardial SPECT after adenosine-stress. Measured hemodynamic parameters, EDV, ESV, stroke volume, EF, cardiac output and cardiac index were compared between the two groups. For comparison, similar-aged two male groups with matched numbers were also studied. There was no significant difference in hemodynamic parameters. EDV, ESV, stroke volume, EF, or cardiac output between the post-menopausal and pre-menopausal women. However, post-menopausal women have a smaller cardiac index (mean: 1.95 L/min/m2 vs 2.20 L/min/m2; p=0.045) and adenosine-induced HR increase (mean : 80.5/min vs 89.7/min ; p=0.03), compared to the pre-menopausal women. On the contrary, the two male groups of the same age range and numbers with the women groups showed no significant difference in any myocardial parameters. These results suggest that menopause may be correlated with reduced increase in cardiac index and HR increase after adenosine-stress.

  13. Experiencias para observar el fenómeno de fluorescencia con luz ultravioleta

    Directory of Open Access Journals (Sweden)

    Heredia Avalos, S.

    2008-09-01

    Full Text Available La fluorescencia tiene lugar cuando una sustancia emite luz visible al absorber radiación de una longitud de onda menor, como por ejemplo luz ultravioleta. La diferencia entre la energía absorbida (del fotón ultravioleta y la emitida (del fotón visible se disipa en forma de calor. Se dice que la sustancia posee fluorescenciacuando este proceso es muy rápido; si es más lento se dice que la sustancia posee fosforescencia. A continuación se describen varias experiencias sencillas para poner de manifiesto el fenómeno de fluorescencia. Todas ellas requieren de reactivos y materiales fácilmente accesibles y asequibles y se pueden realizar con alumnos de secundaria o de bachillerato para poner de manifiesto este fenómeno. Además, también se propone una experiencia en la que se observa la reversibilidad de las reacciones químicas ácido-base a través de la fluorescencia.

  14. Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting

    International Nuclear Information System (INIS)

    Giubbini, Raffaele; Rossini, Pierluigi; Bertagna, Francesco; Bosio, Giovanni; Paghera, Barbara; Pizzocaro, Claudio; Canclini, Silvana; Terzi, Arturo; Germano, Guido

    2004-01-01

    The aim of this study was the evaluation of septal wall motion, perfusion and wall thickening after CABG in two groups of consecutive patients, one with grafted left anterior coronary artery and no history of myocardial infarction, and the other with previous anteroseptal myocardial infarction and impaired septal motion before surgery. The issue addressed was the ability of gated SPECT to differentiate between true paradoxical septal motion, characterised by paradoxical wall motion, depressed ejection fraction (EF), poor viability and compromised wall thickening, and pseudo-paradoxical motion, characterised by abnormal wall motion and regional EF but preserved perfusion and wall thickening. One hundred and thirty-two patients with previous anterior myocardial infarction, 82 patients with left anterior descending coronary disease and no history of myocardial infarction and 27 normal subjects underwent rest gated SPECT after 99m Tc-sestamibi injection, according to the standard QGS protocol. Quantitative regional EF, regional perfusion, regional wall motion and regional wall thickening were determined using a 20-segment model. Despite the presence of similar regional wall motion impairment in patients with and patients without septal infarction, in terms of regional EF (2.5%±3% vs 1.9%±4.9% p=NS) and inward septal motion (3±4.9 mm vs 2.3±6.1 mm p=NS), significant differences were observed in both perfusion (74.7%±6.2% vs 63.3%±13%, p>0.0001) and regional wall thickening (17.2%±7.4% vs 12.6%±7.2%, p>0.0001). Gated SPECT with perfusion tracers can reliably differentiate pseudo-paradoxical from true paradoxical septal motion in patients with previous CABG, and it may be the method of choice for evaluating left ventricular performance in this patient population. (orig.)

  15. Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting.

    Science.gov (United States)

    Giubbini, Raffaele; Rossini, Pierluigi; Bertagna, Francesco; Bosio, Giovanni; Paghera, Barbara; Pizzocaro, Claudio; Canclini, Silvana; Terzi, Arturo; Germano, Guido

    2004-10-01

    The aim of this study was the evaluation of septal wall motion, perfusion and wall thickening after CABG in two groups of consecutive patients, one with grafted left anterior coronary artery and no history of myocardial infarction, and the other with previous anteroseptal myocardial infarction and impaired septal motion before surgery. The issue addressed was the ability of gated SPECT to differentiate between true paradoxical septal motion, characterised by paradoxical wall motion, depressed ejection fraction (EF), poor viability and compromised wall thickening, and pseudo-paradoxical motion, characterised by abnormal wall motion and regional EF but preserved perfusion and wall thickening. One hundred and thirty-two patients with previous anterior myocardial infarction, 82 patients with left anterior descending coronary disease and no history of myocardial infarction and 27 normal subjects underwent rest gated SPECT after 99mTc-sestamibi injection, according to the standard QGS protocol. Quantitative regional EF, regional perfusion, regional wall motion and regional wall thickening were determined using a 20-segment model. Despite the presence of similar regional wall motion impairment in patients with and patients without septal infarction, in terms of regional EF (2.5%+/-3% vs 1.9%+/-4.9% p=NS) and inward septal motion (3+/-4.9 mm vs 2.3+/-6.1 mm p=NS), significant differences were observed in both perfusion (74.7%+/-6.2% vs 63.3%+/-13%, p>0.0001) and regional wall thickening (17.2%+/-7.4% vs 12.6%+/-7.2%, p>0.0001). Gated SPECT with perfusion tracers can reliably differentiate pseudo-paradoxical from true paradoxical septal motion in patients with previous CABG, and it may be the method of choice for evaluating left ventricular performance in this patient population.

  16. Value of gated SPECT in the analysis of regional wall motion of the interventricular septum after coronary artery bypass grafting

    Energy Technology Data Exchange (ETDEWEB)

    Giubbini, Raffaele; Rossini, Pierluigi; Bertagna, Francesco; Bosio, Giovanni; Paghera, Barbara; Pizzocaro, Claudio; Canclini, Silvana; Terzi, Arturo [Spedali Civili di Brescia, Department of Nuclear Medicine, Brescia (Italy); Germano, Guido [Cedars-Sinai Medical Center, Artificial Intelligence Program, Department of Medicine, Los Angeles, CA (United States)

    2004-10-01

    The aim of this study was the evaluation of septal wall motion, perfusion and wall thickening after CABG in two groups of consecutive patients, one with grafted left anterior coronary artery and no history of myocardial infarction, and the other with previous anteroseptal myocardial infarction and impaired septal motion before surgery. The issue addressed was the ability of gated SPECT to differentiate between true paradoxical septal motion, characterised by paradoxical wall motion, depressed ejection fraction (EF), poor viability and compromised wall thickening, and pseudo-paradoxical motion, characterised by abnormal wall motion and regional EF but preserved perfusion and wall thickening. One hundred and thirty-two patients with previous anterior myocardial infarction, 82 patients with left anterior descending coronary disease and no history of myocardial infarction and 27 normal subjects underwent rest gated SPECT after {sup 99m}Tc-sestamibi injection, according to the standard QGS protocol. Quantitative regional EF, regional perfusion, regional wall motion and regional wall thickening were determined using a 20-segment model. Despite the presence of similar regional wall motion impairment in patients with and patients without septal infarction, in terms of regional EF (2.5%{+-}3% vs 1.9%{+-}4.9% p=NS) and inward septal motion (3{+-}4.9 mm vs 2.3{+-}6.1 mm p=NS), significant differences were observed in both perfusion (74.7%{+-}6.2% vs 63.3%{+-}13%, p>0.0001) and regional wall thickening (17.2%{+-}7.4% vs 12.6%{+-}7.2%, p>0.0001). Gated SPECT with perfusion tracers can reliably differentiate pseudo-paradoxical from true paradoxical septal motion in patients with previous CABG, and it may be the method of choice for evaluating left ventricular performance in this patient population. (orig.)

  17. Gated single photon emission computer tomography for the detection of silent myocardial ischemia

    International Nuclear Information System (INIS)

    Pena Q, Yamile; Coca P, Marco Antonio; Batista C, Juan Felipe; Fernandez-Britto, Jose; Quesada P, Rodobaldo; Pena C; Andria

    2009-01-01

    Background: Asymptomatic patients with severe coronary atherosclerosis may have a normal resting electrocardiogram and stress test. Aim: To assess the yield of Gated Single Photon Emission Computer Tomography (SPECT) for the screening of silent myocardial ischemia in type 2 diabetic patients. Material and methods: Electrocardiogram, stress test and gated-SPECT were performed on 102 type 2 diabetic patients aged 60 ± 8 years without cardiovascular symptoms. All subjects were also subjected to a coronary angiography, whose results were used as gold standard. Results: Gated-SPECT showed myocardial ischemia on 26.5% of studied patients. The sensibility, specificity, accuracy, positive predictive value and negative predictive value were 92.3%, 96%, 95%, 88.8%, 97.3%, respectively. In four and six patients ischemia was detected on resting electrocardiogram and stress test, respectively. Eighty percent of patients with doubtful resting electrocardiogram results and 70% with a doubtful stress test had a silent myocardial ischemia detected by gated-SPECT. There was a good agreement between the results of gated-SPECT and coronary angiography (k =0.873). Conclusions: Gated-SPECT was an useful tool for the screening of silent myocardial ischemia

  18. Matemática y Publicidad: Una experiencia con datos reales

    Directory of Open Access Journals (Sweden)

    Danilo Díaz Levicoy

    2016-04-01

    Full Text Available En este artículo se presentan los resultados de una experiencia de aula, con estudiantes de secundaria, centrado en análisis del Índice de Masa Corporal (IMC de los estudiantes de un colegio chileno y la creación de afiches publicitarios a partir de esta información. Entre los resultados se destacan: la importancia de innovar en la enseñanza de la matemática; los proyectos estadísticos como elementos que favorecen el aprendizaje y el trabajo en equipo; la aplicabilidad de la matemática en la creación de publicidad; la potenciación de habilidades no matemáticas.

  19. Assessment of left ventricular function by electrocardiogram-gated myocardial single photon emission computed tomography using quantitative gated single photon emission computed tomography software

    International Nuclear Information System (INIS)

    Morita, Koichi; Adachi, Itaru; Konno, Masanori

    1999-01-01

    Electrocardiogram (ECG)-gated myocardial single photon emission computed tomography (SPECT) can assess left ventricular (LV) perfusion and function easily using quantitative gated SPECT (QGS) software. ECG-gated SPECT was performed in 44 patients with coronary artery disease under post-stress and resting conditions to assess the values of LV functional parameters, by comparison to LV ejection fraction derived from gated blood pool scan and myocardial characteristics. A good correlation was obtained between ejection fraction using QGS and that using cardiac blood pool scan (r=0.812). Some patients with myocardial ischemia had lower ejection fraction under post-stress compared to resting conditions, indicating post-stress LV dysfunction. LV wall motion and wall thickening were significantly impaired in ischemic and infarcted myocardium, and the degree of abnormality in the infarcted areas was greater than in the ischemia area. LV functional parameters derived using QGS were useful to assess post-stress LV dysfunction and myocardial viability. In conclusion, ECG-gated myocardial SPECT permits simultaneous quantitative assessment of myocardial perfusion and function. (author)

  20. Influence of magnification on the calculated value of left ventricular ejection fraction and volumes using quantitative gated perfusion SPECT

    International Nuclear Information System (INIS)

    Nunez, M.; Beretta, M.; Alonso, O.; Alvarez, B.; Canepa, J.; Mut, F.

    2002-01-01

    Aim: To compare left ventricular ejection fraction (LVEF), end-diastolic volumes (EDV) and end-systolic volumes (ESV) measured by quantitative gated SPECT (QGSPECT) in studies acquired with and without magnification factor (zoom). Material and Methods: We studied 30 consecutive patients (17 men, ages 61±14 years) referred for myocardial perfusion evaluation with a 2-day protocol. Studies were performed after injection of 925 MBq (25 mCi) of 99mTc-MIBI in the resting state. Gated SPECT was first acquired using a x2 zoom factor and immediately repeated with x1 zoom (no magnification), using a 64x64 matrix and 8 frames/cardiac cycle. Patients with arrhythmia were not included in the investigation. According to the median EDV calculated with the x2 zoom acquisition, the population was further divided in two sub-groups regarding the size of the LV cavity. Average LVEF, EDV, ESV and difference between values (delta) were then calculated for the total population and for each sub-group (a and b). Results: For the total population, results are expressed.Pearson correlation showed r=0.954 between LVEF with and without zoom (p<0.0001), but linear regression analysis did not fit a specific model (p=0.18). Median EDV with zoom was 92.5 ml, allowing to separate 15 cases with EDV above (a) and 15 below that value (b). Results for both sub-groups are presented. Conclusion: Calculated LVEF is higher with no zoom, at the expense of decreasing both EDV and ESV. Although differences were very significant for all parameters, ESV changes were specially relevant with no zoom, particularly in patients with smaller hearts. Although good correlation was found between LVEF with and without zoom, no specific correction factor was found to convert one value into the other. Magnification factor should be kept constant in gated SPECT if calculated LVEF values QGSPECT are expected to be reliable, and validation of the method using different zoom factors should be considered

  1. Grupos focales de discusión: estrategia para la investigación sobre salud sexual con adolescentes con experiencia de vida en calle en Medellín, Colombia

    Directory of Open Access Journals (Sweden)

    Diana Castro A

    2016-09-01

    Full Text Available La intención de este artículo es evidenciar la importancia de los grupos focales de discusión como estrategia metodológica para la recolección de información en el trabajo con adolescentes institucionalizados con experiencia de vida en calle y, al mismo tiempo, mostrar su valor en el abordaje de la salud sexual con esta población, en tanto que permite una interacción flexible y reflexiva entre investigadores y participantes, así como de los participantes entre sí. El valor de esta estrategia metodológica es sustentado en este artículo mediante testimonios y resultados obtenidos durante su implementación en el estudio llevado a cabo con adolescentes institucionalizados entre 2013 y 2014 en Medellín. Se espera con este reducir las creencias de profesionales con respecto a las limitaciones de la estrategia para abordar temáticas relacionadas con la salud sexual de este grupo poblacional. Los resultados se articulan en cuatro categorías: conocimientos y percepciones sobre vih e its, salud sexual y reproductiva (ssr, el lenguaje en la ssr, y acceso y uso de las tecnologías de la información y la comunicación (tic. De esta manera, se deja de manifiesto el aporte y potencial de la estrategia para el abordaje del tema y para el acercamiento e interacción con adolescentes con experiencia de vida en calle.

  2. Combination of physical exercise and adenosine improves accuracy of automatic calculation of stress LVEF in gated SPECT using QGS software

    International Nuclear Information System (INIS)

    Tehranipour, N.; AL-Nahhas, A.; Towey, D.

    2005-01-01

    Combining exercise and adenosine during the stress phase of myocardial perfusion imaging (MPI) is known to reduce adverse effects and improve image quality. The aim of this study was to assess whether it can also improve the automatic calculation of left ventricular ejection fraction (LVEF) by QGS software package, during the stress phase of Gated SPECT. One hundred patients who had stress Gated SPECT were retrospectively included in this study. Gated data of those who had adenosine only (50 patients = group A) was compared with those obtained in another group of 50 patients who had added bicycle exercise (Group B). All had identical image acquisition protocol using 99mT c-tetrofosmine. Clinical adverse effects, changes in blood pressure (BP), heart rate (HR), and ECG were monitored. Visual assessment of subdiaphragmatic uptake and accuracy of automatic regions of interest (ROI's) drawn by the software were noted. Regions of interest that involved sub-diaphragmatic uptake and resulting in low LVEF were manually adjusted to include the left ventricle only, and the frequency of manual adjustment was noted. No significant difference was noted in age, sex, baseline BP and HR between groups A and B. Adverse effects occurred less often in group B compared to group A (12% vs. 24%, p = 0.118). Maximum HR and BP achieved during stress were significantly higher in group B compared to group A (p 0.025, p = 0.001 respectively). The number of patients who had faulty ROI's and low LVEF, who needed manual adjustment of ROI.s, were higher in group A compared to group B (16% vs. 6%, p = 0.025). The values of LVEF showed significant improvement following manual adjustment of ROI's, increasing from a mean of 19.63 ± 15.96 to 62.13 ± 7.55 (p = 0.0001) and from 17.33 ± 9.5 to 49.67 ± 7.7 (p = 0.0014) in groups A and B respectively. The addition of exercise to adenosine significantly improves the automatic calculation of LVEF by QGS software during Gated SPECT and reduces the need

  3. Vivir con un desfibrilador automático implantable: un estudio cualitativo de las experiencias de los pacientes

    Directory of Open Access Journals (Sweden)

    Inmaculada Paneque Sánchez-Toscano

    2014-06-01

    Full Text Available Objetivo principal: Conocer la experiencia de los pacientes portadores de Desfibrilador Automático Implantable (DAI de la Unidad de Electrofisiología y Arritmias del Hospital Universitario Virgen del Rocío de Sevilla. Metodología: Estudio cualitativo mediante entrevistas semiestructuradas a 11 personas con DAI implantado. Se realizó un análisis de contenido teniendo en cuenta el objetivo de la investigación, las categorías de análisis creadas y las emergentes. Resultados principales: Los temas identificados fueron: la experiencia de vivir con un DAI, las descargas, las estrategias de adaptación, los cambios físicos, emocionales y en el estilo de vida, la vida sexual y la prohibición de conducir. Conclusión principal: Aunque la mayoría de los pacientes aceptan el dispositivo identificando las variables que influyen en la adaptación, existen limitaciones derivadas de cambios físicos, emocionales y en el estilo de vida. Los profesionales sanitarios han de valorar potenciales dificultades de adaptación o alteraciones psicológicas con el fin de facilitar las intervenciones necesarias.

  4. Resultados de diferentes experiencias con búsqueda local aplicadas a problemas de rutas

    Directory of Open Access Journals (Sweden)

    Delgado, C.R.

    2000-01-01

    Full Text Available En los problemas de optimización combinatoria siempre han tenido gran importancia los Algoritmos de Búsqueda Local (o de Búsqueda Vecinal dentro de las técnicas heurísticas, especialmente a partir de la aparición de muchas de las recientes técnicas Metaheurísticas basadas en buena parte en el uso de estos movimientos vecinales. En este trabajo se analizan algunas experiencias relacionadas con estos, aplicados al VRPTW Mixto (carga y descarga. La primera de ellas es la definición y comparación de diferentes tipos de vecindarios para elegir el más adecuado; la segunda es la determinación de qué solución se elige en cada movimiento; la tercera es el uso de una técnica estrategia Búsqueda Local Rápida que puede servir para reducir considerablemente el tiempo de computación en problemas de gran tamaño. Para estas experiencias se usan instancias simuladas.

  5. Two dimensional polar display of cardiac blood pool SPECT

    International Nuclear Information System (INIS)

    Honda, Norinari; Machida, Kikuo; Mamiya, Toshio; Takahashi, Taku; Takishima, Teruo; Hasegawa, Noriko; Hashimoto, Masanori; Ohno, Ken

    1989-01-01

    A new method of ECG gated cardiac blood pool SPECT to illustrate the left ventricular (LV) wall motion in a single static image, two dimensional polar display (2DPD), was described. Circumferential profiles of the difference between end diastolic and end systolic short axis images of the LV were displayed in a similar way to the bull's eye plot of 201 Tl myocardial SPECT. The diagnoses by 2DPDs agreed with those by cinematic displays of ECG gated blood pool SPECT in 74 out of 84 segments (85.5%) of abnormal motion, and 155 out of 168 segments (80.3%) of normal motion. It is concluded that 2DPD can evaluate regional wall motion by a single static image in a significant number of patients, and is also useful in comparing with the bull's eye image of 201 Tl myorcardial SPECT. (orig.)

  6. SISTEMATIZACIÓN DE EXPERIENCIAS DIDÁCTICAS CON DOCENTES: LAS ARTES PLÁSTICAS Y EL CURRÍCULO ESCOLAR

    Directory of Open Access Journals (Sweden)

    Julieta Castro Bonilla

    2008-01-01

    Full Text Available El artículo que presento se refiere al desarrollo de actividades de integración curricular, realizadas con docentes que laboran en instituciones de educación preescolar, primaria, secundaria, y que además forman parte de un proyecto denominado "Primero Aprendo". Deseo rescatar dos aspectos de la experiencia; en primer lugar, una interesante integración entre las artes plásticas y algunos contenidos de los programas de estudio, y en segundo lugar, se resalta un trabajo de equipo en el que participaron, además de la población docente, personas que laboran en actividades culinarias en las mismas instituciones educativas. Durante el desarrollo de las experiencias se enfatizó un trabajo de cooperación, colaboración y entusiasmo, gracias a la apertura mostrada por las direcciones de las instituciones que participaron, situación que favoreció el logro de los objetivos propuestos. Los talleres fueron ofrecidos por profesoras universitarias e investigadoras con experiencia y formación en diferentes especialidades, a saber, música, psicología, educación preescolar y artes plásticas, situación que favoreció en docentes participantes el desarrollo de procesos de integración curricular y aprendizajes, que posteriormente, debían ser aplicados en sus lugares de trabajo.

  7. Experiencias de maternidad adoptiva en Argentina: diálogos con el ideal normativo

    Directory of Open Access Journals (Sweden)

    Mariela Pena

    2015-06-01

    Full Text Available Este artículo aborda la problemática de la adopción focalizando en la categoría de maternidad. Recuperando algunas elaboraciones feministas se ponen en tensión relatos de madres adoptivas con el ideario prevaleciente en torno a la maternidad y su asociación con la “naturaleza” de las mujeres. Se sugiere para el contexto estudiado la persistencia de un ideal normativo que prescribe la centralidad de los aspectos biológicos de la maternidad. En relación a él, exploramos modalidades variables en las cuales diferentes mujeres “resuelven creativamente” sus experiencias, señalando la continuidad de un diálogo con dicho modelo. Asimismo, consideramos algunos entrelazamientos entre los sentidos observados y las influencias del “discurso psi” en la normativización de la crianza y la construcción del ideario de “buena madre”.

  8. [Image fusion of gated-SPECT and CT angiography in coronary artery disease. Importance of anatomic-functional correlation].

    Science.gov (United States)

    Nazarena Pizzi, M; Aguadé Bruix, S; Cuéllar Calabria, H; Aliaga, V; Candell Riera, J

    2010-01-01

    A 77-year old patient was admitted for acute coronary syndrome without ST elevation. His risk was stratified using the myocardial perfusion gated SPECT, mild inferior ischemia being observed. Thus, medical therapy was optimized and the patient was discharged. He continued with exertional dyspnea so a coronary CT angiography was performed. It revealed severe lesions in the proximal RCA. SPECT-CT fusion images correlated the myocardial perfusion defect with a posterior descending artery from the RCA, in a co-dominant coronary area. Subsequently, cardiac catheterism was indicated for his treatment. The current use of image fusion studies is limited to patients in whom it is difficult to attribute a perfusion defect to a specific coronary artery. In our patient, the fusion images helped to distinguish between the RCA and the circumflex artery as the culprit artery of ischemia. Copyright © 2010 Elsevier España, S.L. y SEMNIM. All rights reserved.

  9. Viviendo con los pacientes el sueño del trasplante: una experiencia enfermera

    Directory of Open Access Journals (Sweden)

    Ana Julia Carrillo Algarra

    2014-06-01

    Full Text Available El trasplante renal puede ser una solución para personas que sufren insuficiencia renal crónica. Durante este proceso es de vital importancia el cuidado de enfermería en las diferentes etapas a las que el paciente y su familia se ven enfrentados. Este es el relato biográfico de una enfermera con amplia experiencia en el cuidado de pacientes que han vivido el trasplante renal, que describe diferentes aspectos que se deben tener en cuenta en la relación del equipo interdisciplinario, con el paciente y la familia; a través del mismo narra las vivencias y los sentimientos que afloran en el diario vivir de su labor y comenta su opinión respecto al futuro de la Enfermería en trasplantes.

  10. Variability of left ventricular ejection fraction and volumes with quantitative gated SPECT: influence of algorithm, pixel size and reconstruction parameters in small and normal-sized hearts

    International Nuclear Information System (INIS)

    Hambye, Anne-Sophie; Vervaet, Ann; Dobbeleir, Andre

    2004-01-01

    Several software packages are commercially available for quantification of left ventricular ejection fraction (LVEF) and volumes from myocardial gated single-photon emission computed tomography (SPECT), all of which display a high reproducibility. However, their accuracy has been questioned in patients with a small heart. This study aimed to evaluate the performances of different software and the influence of modifications in acquisition or reconstruction parameters on LVEF and volume measurements, depending on the heart size. In 31 patients referred for gated SPECT, 64 2 and 128 2 matrix acquisitions were consecutively obtained. After reconstruction by filtered back-projection (Butterworth, 0.4, 0.5 or 0.6 cycles/cm cut-off, order 6), LVEF and volumes were computed with different software [three versions of Quantitative Gated SPECT (QGS), the Emory Cardiac Toolbox (ECT) and the Stanford University (SU-Segami) Medical School algorithm] and processing workstations. Depending upon their end-systolic volume (ESV), patients were classified into two groups: group I (ESV>30 ml, n=14) and group II (ESV 2 to 128 2 were associated with significantly larger volumes as well as lower LVEF values. Increasing the filter cut-off frequency had the same effect. With SU-Segami, a larger matrix was associated with larger end-diastolic volumes and smaller ESVs, resulting in a highly significant increase in LVEF. Increasing the filter sharpness, on the other hand, had no influence on LVEF though the measured volumes were significantly larger. (orig.)

  11. Necesidades afectivo-sexuales en personas con discapacidad intelectual. Claves para construir propuestas formativas desde la experiencia subjetiva

    OpenAIRE

    Susana Rojas Pernia; Ignacio Haya Salmón; Susana Lázaro-Visa

    2015-01-01

    El objetivo de este trabajo es presentar las necesidades vividas por un grupo de personas con discapacidad intelectual en torno a la esfera afectiva y sexual. Para ello, a través de una entrevista semiestructurada que abarca diferentes áreas vitales, 16 entrevistados ponen de relieve sus conocimientos y experiencias en torno a la relación de pareja y la intimidad. Sus relatos codificados muestran tres grandes necesidades ilustradas a lo largo del texto: la búsqueda del otro próximo con quien ...

  12. "Necesidades afectivo-sexuales en personas con discapacidad intelectual. Claves para construir propuestas formativas desde la experiencia subjetiva"

    OpenAIRE

    Rojas, S.

    2016-01-01

    El objetivo de este trabajo es presentar las necesidades vividas por un grupo de personas con discapacidad intelectual en torno a la esfera afectiva y sexual. Para ello, a través de una entrevista semiestructurada que abarca diferentes áreas vitales, 16 entrevistados ponen de relieve sus conocimientos y experiencias en torno a la relación de pareja y la intimidad. Sus relatos codificados muestran tres grandes necesidades ilustradas a lo largo del texto: la búsqueda del otro próximo con quien ...

  13. GATE V6: a major enhancement of the GATE simulation platform enabling modelling of CT and radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Jan, S; Becheva, E [DSV/I2BM/SHFJ, Commissariat a l' Energie Atomique, Orsay (France); Benoit, D; Rehfeld, N; Stute, S; Buvat, I [IMNC-UMR 8165 CNRS-Paris 7 and Paris 11 Universities, 15 rue Georges Clemenceau, 91406 Orsay Cedex (France); Carlier, T [INSERM U892-Cancer Research Center, University of Nantes, Nantes (France); Cassol, F; Morel, C [Centre de physique des particules de Marseille, CNRS-IN2P3 and Universite de la Mediterranee, Aix-Marseille II, 163, avenue de Luminy, 13288 Marseille Cedex 09 (France); Descourt, P; Visvikis, D [INSERM, U650, Laboratoire du Traitement de l' Information Medicale (LaTIM), CHU Morvan, Brest (France); Frisson, T; Grevillot, L; Guigues, L; Sarrut, D; Zahra, N [Universite de Lyon, CREATIS, CNRS UMR5220, Inserm U630, INSA-Lyon, Universite Lyon 1, Centre Leon Berard (France); Maigne, L; Perrot, Y [Laboratoire de Physique Corpusculaire, 24 Avenue des Landais, 63177 Aubiere Cedex (France); Schaart, D R [Delft University of Technology, Radiation Detection and Medical Imaging, Mekelweg 15, 2629 JB Delft (Netherlands); Pietrzyk, U, E-mail: buvat@imnc.in2p3.fr [Reseach Center Juelich, Institute of Neurosciences and Medicine and Department of Physics, University of Wuppertal (Germany)

    2011-02-21

    GATE (Geant4 Application for Emission Tomography) is a Monte Carlo simulation platform developed by the OpenGATE collaboration since 2001 and first publicly released in 2004. Dedicated to the modelling of planar scintigraphy, single photon emission computed tomography (SPECT) and positron emission tomography (PET) acquisitions, this platform is widely used to assist PET and SPECT research. A recent extension of this platform, released by the OpenGATE collaboration as GATE V6, now also enables modelling of x-ray computed tomography and radiation therapy experiments. This paper presents an overview of the main additions and improvements implemented in GATE since the publication of the initial GATE paper (Jan et al 2004 Phys. Med. Biol. 49 4543-61). This includes new models available in GATE to simulate optical and hadronic processes, novelties in modelling tracer, organ or detector motion, new options for speeding up GATE simulations, examples illustrating the use of GATE V6 in radiotherapy applications and CT simulations, and preliminary results regarding the validation of GATE V6 for radiation therapy applications. Upon completion of extensive validation studies, GATE is expected to become a valuable tool for simulations involving both radiotherapy and imaging.

  14. Estudio de Caso de la Experiencia Subjetiva del Cuerpo

    Directory of Open Access Journals (Sweden)

    Edith Flores Pérez

    2007-01-01

    Full Text Available Estudio de caso que explora la experiencia subjetiva del cuerpo en la trayectoria con el uso de drogas a través del relato de vida. Se utilizó la entrevista abierta bajo los supuestos metodológicos del relato autobiográfico. Se propuso al participante “Hablar de sí mismo y contar su experiencia con el uso de drogas”. La estrategia analítica se diseñó con base en la propuesta de Barthes (1990 para el análisis estructural de los relatos. Los resultados muestran que en el relato emerge una subjetividad que articula modos de haber sido y ser cuerpo como instancias constitutivas de la existencia. Desde el punto de vista de la corporalidad, la trayectoria con el uso de drogas deviene en una relación de saber-poder con el propio cuerpo, donde la experiencia subjetiva se entreteje en una red de controles y normas sociales. El análisis del cuerpo como experiencia enriquece la comprensión de prácticas como el uso de drogas.

  15. Comparison of myocardial fatty acid metabolism with left ventricular function and perfusion in cardiomyopathies. By 123I-BMIPP SPECT and 99mTc-tetrofosmin electrocardiographically gated SPECT

    International Nuclear Information System (INIS)

    Zhao, Chunlei; Shuke, Noriyuki; Okizaki, Atsutaka

    2003-01-01

    The objective of this study was to investigate myocardial fatty acid metabolism and its relationship with left ventricular (LV) function and perfusion in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). Thirty-nine patients with cardiomyopathies (58±14 y), comprising 15 DCM and 24 HCM, and 9 age-matched healthy controls were studied with 123 I-15-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) and 99m Tc-tetrofosmin (TF) electrocardiographically gated SPECT. As parameters of myocardial fatty acid metabolism, the heart-to-mediastinum ratio (H/M) and global washout of BMIPP were calculated from early and delayed planar images, while regional BMIPP uptake and washout were calculated from SPECT. In TF study, the H/M (H/M-TF) and LV ejection fraction (LVEF) were calculated as global parameters of perfusion and function, while regional TF uptake and wall thickening index were calculated as regional parameters of perfusion and function using the Quantitative Gated SPECT software. The differences in the parameters and the correlations between the parameters from the 2 studies were investigated by one-way ANOVA and multiple linear regression analysis. BMIPP uptake was decreased (p 0.05), but showed a significant correlation with H/M-TF (p 0.05) but had a significant correlation with regional perfusion (p<0.0001) in DCM. In HCM, regional BMIPP parameters showed significant multiple linear correlations with both regional function (p<0.005) and perfusion (p<0.0001). According to the partial correlation coefficients, delayed regional BMIPP uptake was the most significant factor for predicting regional function in HCM, while early regional BMIPP uptake was the only or the most significant factor for predicting regional perfusion in DCM and HCM, respectively. In DCM, BMIPP uptake and washout could not reflect LV function. In HCM, regional delayed BMIPP uptake might be useful for evaluating regional function. In DCM and HCM, early BMIPP uptake might be

  16. ANÁLISIS CRÍTICO DE LA EXPERIENCIA DE UN TRABAJO COLABORATIVO CON MUJERES

    Directory of Open Access Journals (Sweden)

    Gardenia Isabel de Atochita Koh Yah

    2015-01-01

    Full Text Available Se presenta el análisis de una experiencia de trabajo clínico con mujeres, desde la perspectiva de un a psicología clínica incluyente y promotora de la salud, que no solo busca la cura o prevención de enfermedades. Se trabajó desde un paradigma cualitativo con metodología de I nvestigación Acción Participativa (IAP , que reflejara que el trabajo clínico es posible en un contexto comunitario, con el involucramiento y la part icipación activa de las personas. El trabajo se enmarca en el modelo colaborativo que privilegia el lenguaje como elemento constructor y transformador de la realidad. La práctica desarrolló un ejercicio de reflexión, con sentido crítico, sobre la salud y s u promoción. El propósito de estas conversaciones terapéuticas fue contribuir a la ampliación de alternativas que impactaran en el bienest ar de las participantes, es decir, el fin fue la optimización de los recursos de las personas.

  17. Análisis de fase mediante "Gated-SPECT" de perfusión miocárdica para valorar el sincronismo mecánico del ventrículo izquierdo realizado con dos programas distintos de procesamiento

    Directory of Open Access Journals (Sweden)

    Víctor Marín Oyaga

    2016-01-01

    Full Text Available Introducción y objetivos: El análisis de fase mediante Gated- SPECT de perfusión mio - cárdica ( GS-PMI es una nueva herramienta para medir la asincronía ventricular izquierda con importantes aplicaciones clínicas futuras en resincronización e insuficiencia cardiaca. Se puede medir mediante dos programas ( ECTb o QGS C-S . El objetivo es demostrar su factibilidad y verificar si existen diferencias entre ambos. Metodología: Estudio analítico, observacional y retrospectivo en pacientes con GS-PMI normales. Los parámetros obtenidos fueron: la desviación estándar de la fase (DE y el ancho de banda de histograma (AH . La evaluación de la diferencia entre los grupos se realizó usando pruebas para muestras independientes después de analizar la distribución de datos. Nivel de significación p<0,05. Se utilizó SPSS IBM V.21 ®. Resultados: Total pacientes: 193 (104 hombres. Edad media: 64 años (24-89.61/193 procesados con QGS C-S y 132/193 con ECT b. Postestrés: la media de la DE fue 6º±3,7º, con mediana de 5º y rango intercuartílico ( IR :3.6º. La media de AH fue 22,7º±10º, con mediana de 18º y IR :11.5º. Postreposo: la media de la DE fue 5,76º±4,82º y la mediana 4,5º con IR : 3.1º. La media de AH fue 21.67º± 14.06º y la mediana 18º, IR :12º. Entre ambos programas se encontraron diferencias significativas en la DE en postestrés (p=0,001 y postreposo (p=0,019, sin diferencias en el AH postestrés (p=0,31 y postreposo (p=0,18. Conclusión : Realizar el análisis fase de análisis por GS-PMI es factible. Sin embargo, la DE mostró diferencias significativas entre los dos programas. Aunque los valores mostrados podrían ser utilizados como valores normales, se recomienda que estos se obtengan y utilicen para cada programa por separado.

  18. Factors affecting accuracy of ventricular volume and ejection fraction measured by gated Tl-201 myocardial perfusion single photon emission computed tomography

    International Nuclear Information System (INIS)

    Pai, Moon Sun; Yang, You Jung; Im, Ki Chun; Hong, Il Ki; Yun, Sung Cheol; Kang, Duk Hyun; Song, Jae Kwan; Moon, Dae Hyuk

    2005-01-01

    Systemic errors in the gated single photon emission computed tomography (SPECT) measurement of left ventricular (LV) end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) may occur. We evaluated whether patient-related factors affected the accuracy of EDV, ESV, and EF measured by electrocardiogram-gated Tl-201 SPECT. A total of 518 patients without perfusion defects on Tl-201 SPECT or coronary artery disease were studied. EDV, ESV, and EF were measured from echocardiography and adenosine stress/redistribution gated Tl-201 SPECT using commercially available software packages (QGS and 4D-MSPECT). We identified factors affecting the accuracy of gated SPECT via multiple linear regression analysis of the differences between echocardiography and gated SPECT. Gated SPECT analyzed with QGS underestimated EDV and ESV, and overestimated EF, but 4D-MSPECT overestimated all those values (p<0.001). Independent variables that increased the difference in EDV between echocardiography and gated SPECT were decreasing LV end-diastolic wall thickness, decreasing body surface area, female sex and increasing EDV (p< 0.001). Those for ESV were decreasing LV end-systolic wall thickness, female sex, and decreasing ESV (p<0.001). Increasing end-systolic wall thickness, male sex and decreasing age were independent determinants associated with an increased difference in EF (p< 0.001). Adenosine stress SPECT showed significantly higher EDV and ESV values and a lower EF than did redistribution SPECT (p< 0.001). In determination of EF, QGS demonstrated a smaller bias than did 4D-MSPECT. However, in men with LV hypertrophy, 4D-MSPECT was superior to QGS. Systemic error by gated Tl-201 SPECT is determined by individual patient-characteristics

  19. Interpretaciones de la fracción en una experiencia de simulación con geogebra

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    Jhorfy J. Reyes R.

    2016-08-01

    Full Text Available En este trabajo se presenta una experiencia de simulación con GeoGebra vivida por dos estudiantes de nivel medio en Venezuela. Específicamente, se describe la manera en que las estudiantes resuelven la tarea de representar un fenómeno con el software. Durante la simulación, las interpretaciones parte-todo, así como reparto y operador de las fracciones,ayudaron a crear y validar técnicas de localización de puntos característicos de las figuras geométricas asociadas con el fenómeno tratado. La conexión entre las distintas interpretaciones y con otras nociones matemáticas emergentes también se puso de manifiesto. En cuanto al GeoGebra, se resalta el uso de la cuadrícula como referente gráfico que apoyó las reflexiones de las estudiantes a lo largo de la experiencia. AbstractThis paper presents a simulation experience with GeoGebra lived by two average level high school students from Venezuela. Specifically, it describes the way in which students solve the task of representing a phenomenon with the software. During the simulation, the interpretations of being part of a whole, as well as distribution and fractions operator, took place and helped students to create and validate technics to locate characteristic points of the geometrical figures associated with the phenomenon treated. The connection between the different interpretations and other mathematical concepts were also present. Regarding to GeoGebra, it is highlighted the use of the grid as a graphic reference that supported the reflections of the students during the experience.

  20. Aprendizaje con robótica, algunas experiencias

    Directory of Open Access Journals (Sweden)

    Pedro Antonio López Ramírez

    2013-01-01

    Full Text Available Este artículo presenta el análisis de experiencias, revisadas en diversos artículos, acerca de la implementación de la robótica en la educación, con el fin de obtener referentes pertinentes para la construcción de una propuesta para el aprendizaje de la robótica en la educación básica secundaria y media. Se consideran dos ámbitos de aplicación de la robótica en la educación: el primero es el aprendizaje de la robótica mediante la conceptualización de cada uno de los subsistemas de un robot para luego realizar la construcción de robots con diferentes propósitos, en este ámbito el objetivo es desarrollar las competencias, en los estudiantes, para el diseño y construcción de tecnofactos robóticos, mediante un proceso de construcción del conocimiento necesario para hacerlo; el segundo ámbito de aplicación es la utilización de la robótica como medio que motiva y da sentido a la construcción de conocimiento en diversas áreas, promoviendo habilidades y competencias en los estudiantes. Además, el aprendizaje de la robótica y el aprendizaje con robótica pueden ser mediados por la informática, la cual aporta tecnologías y herramientas software como los lenguajes de modelado matemático y simulación, tutoriales multimediales, laboratorios virtuales y remotos, entre otros. Así, este artículo se propone destacar cómo la robótica en el aula de clase permite, por una parte, el enriquecer estrategias de aprendizaje como apoyo a la formación integral de los estudiantes, y por otra, es un campo que presenta una demanda creciente en la atención de docentes e investigadores, así como en los estímulos para su investigación, desarrollo y divulgación de parte del estado.

  1. Apoyando la participación real de las personas con discapacidad intelectual: una experiencia de investigación inclusiva sobre vida independiente

    Directory of Open Access Journals (Sweden)

    María Pallisera Díaz

    2017-06-01

    Full Text Available En nuestro contexto se han desarrollado escasas experiencias de investigación realizadas conjuntamente entre investigadores académicos e investigadores con discapacidad intelectual. Este artículo tiene como finalidad aportar una experiencia de investigación cualitativa sobre vida independiente y discapacidad, desarrollada por las autoras (investigadoras académicas en colaboración con un Consejo Asesor integrado por personas con discapacidad intelectual. Se pretende, además de presentar el desarrollo y resultados de la investigación, explicar cómo se ha construido el proceso de colaboración entre los asesores y las investigadoras de la universidad a lo largo de las distintas fases del estudio. También se van a concretar las estrategias de apoyo que se han ofrecido a los asesores para plantear, finalmente, las reflexiones sobre los principales retos que conlleva avanzar en los procesos de investigación inclusiva. Con ello se pretende contribuir al avance de las investigaciones inclusivas en las que las personas con discapacidad tengan un protagonismo real en el estudio de los problemas que las afectan.

  2. Experiencia con Símbolos y Comprensión de Dibujos en Niños Pequeños de Distintos Contextos Socioeconómicos

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    Analía M. Salsa

    2018-01-01

    Full Text Available El propósito de esta investigación fue explorar las relaciones entre la comprensión temprana de dibujos por parte de niños de nivel socioeconómico medio (nse medio y bajo (nse bajo y las experiencias con símbolos en el contexto familiar. Para ello, 28 niños de entre 30 y 38 meses resolvieron una tarea de correspondencias en la que debían establecer relaciones entre cinco objetos y sus dibujos en lápiz negro. Sus madres contestaron un cuestionario sobre la cantidad y la variedad de imá- genes en los hogares y las actividades compartidas por adultos y niños con estas representaciones. Los resultados muestran que solamente los niños de nse medio demostraron comprender la relación dibujo-referente; el desempeño simbólico se asoció principalmente con la presencia en los hogares de recursos con imágenes para niños (dvd y libros infantiles y con las interacciones adulto-niño con estos recursos, como las experiencias conjuntas con imágenes audiovisuales, la lectura de cuentos y la asistencia materna al dibujar

  3. La experiencia de sufrimiento en cuidadores principales de pacientes con dolor oncológico y no oncológico

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    ALICIA KRIKORIAN D

    2010-06-01

    Full Text Available El objetivo de la investigación es describir la experiencia de sufrimiento de los cuidadores informales de pacientes con dolor oncológico y no oncológico de tres instituciones de salud de Medellín. Es una investigación cualitativa de tipo fenomenológico. La muestra estuvo conformada por 16 cuidadores de pacientes con dolor oncológico y no oncológico. La información se recolectó a través de una entrevista semiestructurada y se cuantificó el nivel de sufrimiento por medio del termómetro emocional como complemento al enfoque cualitativo. Los datos obtenidos se analizaron por medio de categorías y perfiles previamente definidos, lo cual dio cuenta del significado, el nivel y los factores de sufrimiento más comunes en los cuidadores entrevistados. Los resultados evidenciaron que la mayoría de los cuidadores experimentaron altos niveles de sufrimiento. Reportaron sentimientos de tristeza y satisfacción contradictoriamente. En la esfera cognitiva, asociaron el sufrimiento con dolor y con el hacer bien su actividad; y en el área conductual, refirieron que el sufrimiento se relacionaba con la dificultad para el control de los síntomas físicos del paciente, y con el aplazamiento de actividades propias de su vida. En conclusión, el apoyo psicosocial recibido por los cuidadores no fue percibido como factor protector para la disminución del sufrimiento; el tipo de dolor estaba relacionado con la experiencia de sufrimiento y el rol de cuidadores, quienes en su mayoría eran mujeres cuidadoras de pacientes con dolor oncológico. Los cuidadores entrevistados estaban en riesgo de presentar Burnout debido a las múltiples demandas propias de su rol.

  4. Performance of Thallium-201 Electrocardiography-gated Myocardial Perfusion Single Photon Emission Computed Tomography to Assess Left Ventricular Function

    Directory of Open Access Journals (Sweden)

    Guang-Uei Hung

    2005-05-01

    Full Text Available This study evaluated the performance of gated single photon emission computed tomography (SPECT with thallium-201 (201Tl in assessing left ventricular ejection fraction (LVEF, end-diastolic volume (EDV, and end-systolic volume (ESV in Taiwanese by determining repeatability and correlation with two-dimensional (2D echocardiography. A total of 18 patients underwent two sequential gated SPECT acquisitions within 30 minutes in the resting state to assess repeatability. Another 28 patients who underwent gated SPECT and 2D echocardiography within 7 days were included for comparison. The two sequential measurements were well correlated with respect to LVEF, EDV, and ESV (r = 0.97, 0.95, and 0.97, respectively, all p < 0.0001. Bland-Altman analysis revealed that two standard deviations of the absolute difference between the two sequential measurements for LVEF, EDV, and ESV were 6.4%, 16.8 mL, and 8.6 mL, respectively. For LVEF, EDV, and ESV, correlations between redistribution 201Tl-gated SPECT and echocardiography were also excellent (all r = 0.83, p < 0.0001. LVEF was similar with 201Tl-gated SPECT and echocardiography, but EDV and ESV were significantly higher with echocardiography (p < 0.05. Our study revealed that 201Tl-gated SPECT has high repeatability and excellent correlation with echocardiography for the assessment of LVEF and volumes in Taiwanese. These results support the clinical application of gated SPECT in routine 201Tl myocardial perfusion imaging in Taiwanese.

  5. Revascularización miocárdica con uso de doble arteria mamaria interna y morbilidad esternal. Experiencia de un centro

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    Sara Badia

    2017-05-01

    Conclusiones: En nuestra experiencia, la utilización de doble mamaria no se acompañó de mayor incidencia de dehiscencia esternal, pero si con problemas de infección superficial de la herida, sobre todo en el grupo de pacientes mujeres, con insuficiencia renal y transfundidos en quirófano. Para mantener el beneficio de la doble mamaria en estos pacientes, deberíamos ser especialmente cuidadosos e implementar nuevas estrategias de cierre esternal.

  6. Cluster computing software for GATE simulations

    International Nuclear Information System (INIS)

    Beenhouwer, Jan de; Staelens, Steven; Kruecker, Dirk; Ferrer, Ludovic; D'Asseler, Yves; Lemahieu, Ignace; Rannou, Fernando R.

    2007-01-01

    Geometry and tracking (GEANT4) is a Monte Carlo package designed for high energy physics experiments. It is used as the basis layer for Monte Carlo simulations of nuclear medicine acquisition systems in GEANT4 Application for Tomographic Emission (GATE). GATE allows the user to realistically model experiments using accurate physics models and time synchronization for detector movement through a script language contained in a macro file. The downside of this high accuracy is long computation time. This paper describes a platform independent computing approach for running GATE simulations on a cluster of computers in order to reduce the overall simulation time. Our software automatically creates fully resolved, nonparametrized macros accompanied with an on-the-fly generated cluster specific submit file used to launch the simulations. The scalability of GATE simulations on a cluster is investigated for two imaging modalities, positron emission tomography (PET) and single photon emission computed tomography (SPECT). Due to a higher sensitivity, PET simulations are characterized by relatively high data output rates that create rather large output files. SPECT simulations, on the other hand, have lower data output rates but require a long collimator setup time. Both of these characteristics hamper scalability as a function of the number of CPUs. The scalability of PET simulations is improved here by the development of a fast output merger. The scalability of SPECT simulations is improved by greatly reducing the collimator setup time. Accordingly, these two new developments result in higher scalability for both PET and SPECT simulations and reduce the computation time to more practical values

  7. Assessment of left ventricular function using 201Tl electrocardiogram-gated myocardial single photon emission computed tomography

    International Nuclear Information System (INIS)

    Nishikubo, Naotsugu; Tamai, Hiroyuki

    2013-01-01

    Advances in computed tomography (CT) technology make it possible to obtain left ventricular wall motion using 3D reconstruction. In this study, we compared the images obtained from CT and 201 Tl electrocardiogram (ECG) gated single photon emission computed tomography (SPECT). In 20 patients with ischemic heart disease, we performed 201 Tl ECG gated SPECT (GE Healthcare Millennium VG) and ECG gated CT (Philips Medical Systems Brilliance iCT) to evaluate of left ventricular wall motion during the resting phase. In SPECT, left ventricular images were reconstructed using quantitative gated SPECT (QGS) software. In CT, the images were reconstructed using Virtual Place (AZE Software). The left ventricle was classified into five regions (anterior, lateral, inferior, septal, and apical). The amplitude of the wall motion was classified into five grades according to AHA classification. The values of the wall motion were separately checked by two radiographers. Assessment of left ventricular function myocardial wall movement using the three-dimensional movie display with ECG gated myocardial SPECT data was in agreement with the evaluation by cardiac CT inspection, and corresponded with wall motion in 88 of all 100 segments. SPECT analysis has the same quantity as that of obtained from CT for evaluation of left ventricular wall motion. (author)

  8. ENCUENTROS, NARRATIVAS Y EXPERIENCIAS CON JÓVENES DESVINCULADOS DEL CONFLICTO ARMADO COLOMBIANO

    Directory of Open Access Journals (Sweden)

    Lucas Marín Aponte

    2015-12-01

    Full Text Available El presente texto nos aproxima a la compresión de experiencias y desafíos que viven los jóvenes desvinculados de diferentes grupos armados, luego de egresar de los programas de atención a víctimas, en su proceso de reintegración a la vida civil. A través de diversos encuentros, se propiciaron espacios de diálogos que permitieron conocer sus testimonios, con el objetivo de implementar estrategias pedagógicas para atender estas poblaciones, y ahondar en nuestra realidad nacional. El reclutamiento forzado de menores, es un fenómeno social de impacto internacional que ha motivado múltiples estudios en especial desde las ciencias sociales, este fenómeno se presenta con mayor frecuencia en zonas rurales marginadas por el Estado, dominadas por estados paralelos o repúblicas independientes, dedicadas a actividades ilícitas. Hemos visto la necesidad de promover la creación de redes de apoyo institucionales y comunitarias que fortalezcan dichos procesos de reinserción ante un eventual acuerdo de paz en Colombia.

  9. Contacto precoz con la realidad asistencial: una experiencia piloto en medicina

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    J.E. Baños

    Full Text Available Introducción: Varios estudios han sugerido que el contacto precoz del estudiante de medicina con la realidad asistencial puede tener unos efectos beneficiosos sobre su motivación, el conocimiento de la relación médico-paciente y la aceptación de la importancia de las materias médicas básicas. En el nuevo grado conjunto de Medicina de la Universitat Autònoma de Barcelona y la Universitat Pompeu Fabra se ha incorporado una asignatura denominada 'Prácticas de Grado' que se imparte durante los tres primeros años, destinada a permitir el contacto de los estudiantes con la asistencia primaria, los equipos de enfermería y los centros sociosanitarios. El presente artículo describe la experiencia y la opinión de los estudiantes que la cursaron durante el primer año. Materiales y métodos: El artículo describe las características académicas de la asignatura. Se realizó una encuesta a los estudiantes al finalizar la asignatura para evaluar su grado de satisfacción y su percepción sobre el cumplimiento de los objetivos y las competencias que debían alcanzarse. Resultados: Existió una elevada satisfacción con la nueva actividad y una percepción entre los estudiantes de que las competencias preestablecidas se habían alcanzado en su mayor parte. Conclusión: El contacto precoz con la realidad asistencial es un elemento esencial para la comprensión de la actividad médica por los estudiantes de medicina de primer año.

  10. Influence of Respiratory Gating, Image Filtering, and Animal Positioning on High-Resolution Electrocardiography-Gated Murine Cardiac Single-Photon Emission Computed Tomography

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    Chao Wu

    2015-01-01

    Full Text Available Cardiac parameters obtained from single-photon emission computed tomographic (SPECT images can be affected by respiratory motion, image filtering, and animal positioning. We investigated the influence of these factors on ultra-high-resolution murine myocardial perfusion SPECT. Five mice were injected with 99m technetium (99mTc-tetrofosmin, and each was scanned in supine and prone positions in a U-SPECT-II scanner with respiratory and electrocardiographic (ECG gating. ECG-gated SPECT images were created without applying respiratory motion correction or with two different respiratory motion correction strategies. The images were filtered with a range of three-dimensional gaussian kernels, after which end-diastolic volumes (EDVs, end-systolic volumes (ESVs, and left ventricular ejection fractions were calculated. No significant differences in the measured cardiac parameters were detected when any strategy to reduce or correct for respiratory motion was applied, whereas big differences (> 5% in EDV and ESV were found with regard to different positioning of animals. A linear relationship (p < .001 was found between the EDV or ESV and the kernel size of the gaussian filter. In short, respiratory gating did not significantly affect the cardiac parameters of mice obtained with ultra-high-resolution SPECT, whereas the position of the animals and the image filters should be the same in a comparative study with multiple scans to avoid systematic differences in measured cardiac parameters.

  11. Factores de personalidad, perceptuales y cognitivas asociadas con las experiencias anómalo/paranormales en personal de enfermería

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    Alejandro Parra

    2017-09-01

    Cómo citar este artículo: Parra A. Factores de personalidad, perceptuales y cognitivas asociadas con las experiencias anómalo/paranormales en personal de enfermería. Rev Cuid. 2017; 8(3: 1733-48. http://dx.doi.org/10.15649/cuidarte.v8i3.408

  12. Avaliação da perfusão e função miocárdicas em vítimas de escorpionismo utilizando o Gated-SPECT Evaluación de la perfusión y función miocárdicas en víctimas de escorpionismo utilizando el Gated-SPECT Assessment of myocardial perfusion and function in victims of scorpion envenomation using Gated-SPECT

    Directory of Open Access Journals (Sweden)

    Alexandre Baldini de Figueiredo

    2010-04-01

    énico y el edema agudo de pulmón son las principales causas de óbito en pacientes con escorpionismo, cuyo mecanismo fisiopatológico es todavía controvertido. OBJETIVO: Investigar la correlación entre los disturbios de la perfusión miocárdica y la función contráctil del ventrículo izquierdo, en victimas de escorpionismo. MÉTODOS: Quince pacientes fueron sometidos a centellografía de perfusión miocárdica sincronizada con ECG (Gated SPECT, dentro de 72 horas y 15 días tras el accidente con escorpión. Las imágenes se analizaron visualmente por score semicuantitativo de perfusión (0 = normal, 4 = ausente y movilidad (0 = normal, 4 = acinético, utilizando modelo de 17 segmentos. Para cada paciente se calcularon scores sumados de perfusión (ESP y movilidad (ESM. La fracción de eyección (FEVI se calculó por software comercialmente disponible. RESULTADOS: En la evaluación inicial, 12 de los 15 pacientes presentaron alteraciones de la contractilidad y de la perfusión miocárdica. El ESP fue de 12,5 ± 7,3, el ESM de 17,0 ± 12, 8 y la FEVI de 44,6 ± 16,0%. Hubo correlación positiva entre el ESP y el ESM (r = 0,68; p = 0,005 y negativa entre el ESP y la FEVI (r = -0,75; p = 0,0021. Los estudios de seguimiento expresaron recuperación de la contractilidad global (FEVI de 68,9 ± 9,5, p = 0,0002, segmentar (ESM 2,6 ± 3,1, p = 0,0009 y de la perfusión (ESP 3,7 ± 3,3, p = 0,0003. La mejora de la FEVI se correlacionó positivamente con la mejora del ESP (r = 0,72; p = 0,0035. CONCLUSIÓN: Alteraciones perfusionales miocárdicas son comunes en el envenenamiento por escorpión y se correlacionan topográficamente con la disfunción contráctil. La recuperación de la contractilidad se correlaciona con la reversibilidad de los defectos perfusionales. Estos hallazgos sugieren la participación de alteraciones perfusionales miocárdicas en la fisiopatología de esta forma de insuficiencia ventricular aguda.BACKGROUND: Cardiogenic shock and acute pulmonary edema

  13. Experiencia de cuidadores familiares de mujeres con cáncer de mama: una revisión integradora

    Directory of Open Access Journals (Sweden)

    María Mercedes Moreno-González

    2018-01-01

    Full Text Available Objetivo: identificar la evidencia científica de enfermería relacionada con la experiencia de los cuidadores familiares de mujeres con cáncer de mama.Metodología: revisión integradora siguiendo los lineamientos de Ganong; búsqueda en bases de datos: EMBASE, OVID, PUBMED, SAGE journals, SCIELO, Google Academic, ISI Web of Science y SCOPUS, artículos publicados entre los años 2000 y 2016. Resultados: se incluyeron 18 artículos producto de investigaciones primarias de tipo cualitativo, cuyos referentes teórico-metodológicos fueron fenomenología y teoría fundamentada, las técnicas de recolección de datos fueron la entrevista semiestructurada y en profundidad. Se presentan y discuten como hallazgos las siguientes categorías: impacto del diagnóstico; lo que implica ser cuidador; efectos en el cuidador; estrategias de afrontamiento; cambios en los roles y las relaciones; apoyo social. Conclusiones: las características de los cuidadores son variables, es necesario conocer sobre la cultura y recursos propios de cada contexto. Los cuidadores requieren información clara y oportuna en relación su función y las habilidades a desarrollar, especialmente para otorgar apoyo emocional. Es necesaria la indagación de dichas experiencias en el contexto mexicano. Las relaciones padres e hijos en las familias de mujeres con cáncer de mama es un asunto poco estudiado, se requieren futuros estudios en este tema.

  14. Detection of myocardial viability by means of Single Proton Emission Computed Tomography (Perfused SPECT) dual 201 Tl (rest of 15 minutes, 24 late hours and 24 hours reinjection) and gated-SPECT 99m Tc-SESTAMIBI in effort or stimulation of the coronary reserves

    International Nuclear Information System (INIS)

    Mendoza V, R.

    2004-01-01

    The objective of this work was to determine if the images of SPECT 201 TI in rest of 15 minutes, 24 late hours and Gated-SPECT 99m Tc-SESTAMIBI in effort or stimulation of coronary reservation correlate with the study of 24 hours post reinjection of 201 TI to determine the presence of having knitted viable myocardium. Material and methods: 29 patients were studied with coronary arterial illness (EAC) to who are carried out SPECT 201 TI in rest with images of 15 minutes, 24 late hours and 24 hours reinjection, by means of the administration of 201 TI to dose of 130 MBq and reinjection with 37 MBq. and Gated-SPECT 99m Tc-SESTAMIBI in effort or stimulation of coronary reservation, later to the administration of 1110 MBq. Results: 29 patients were included according to inclusion approaches and exclusion, of those which 22 (75.86%) they correspond at the masculine sex and 7 (24.13%) to the feminine one, with an average of 62.1 year-old age, 2320 segments myocardial were analysed so much it is phase post-effort as rest; they were diagnosed a total of 264 segments with heart attack, of which viability myocardium was observed in 174 segments. The statistical tests are analysis of frequencies. The non parametric test of Wilcoxon and Mann-Whitney. Conclusions: the viability myocardial at the 24 late hours and 24 hours reinjection was similar; significant difference exists between the study of 15 minutes and 24 hours reinjection, ischemic illness was also demonstrated in territories different to the heart attack area in the studies of 15 minutes, late 24 hours and 24 hours reinjection. (Author)

  15. Validation of Left Ventricular Ejection Fraction with the IQ•SPECT System in Small-Heart Patients.

    Science.gov (United States)

    Yoneyama, Hiroto; Shibutani, Takayuki; Konishi, Takahiro; Mizutani, Asuka; Hashimoto, Ryosuke; Onoguchi, Masahisa; Okuda, Koichi; Matsuo, Shinro; Nakajima, Kenichi; Kinuya, Seigo

    2017-09-01

    The IQ•SPECT system, which is equipped with multifocal collimators ( SMART ZOOM) and uses ordered-subset conjugate gradient minimization as the reconstruction algorithm, reduces the acquisition time of myocardial perfusion imaging compared with conventional SPECT systems equipped with low-energy high-resolution collimators. We compared the IQ•SPECT system with a conventional SPECT system for estimating left ventricular ejection fraction (LVEF) in patients with a small heart (end-systolic volume IQ•SPECT. End-systolic volume, end-diastolic volume, and LVEF were calculated using quantitative gated SPECT (QGS) and cardioREPO software. We compared the LVEF from gated myocardial perfusion SPECT to that from echocardiographic measurements. Results: End-diastolic volume, end-systolic volume, and LVEF as obtained from conventional SPECT, IQ•SPECT, and echocardiography showed a good to excellent correlation regardless of whether they were calculated using QGS or using cardioREPO. Although LVEF calculated using QGS significantly differed between conventional SPECT and IQ•SPECT (65.4% ± 13.8% vs. 68.4% ± 15.2%) ( P = 0.0002), LVEF calculated using cardioREPO did not (69.5% ± 10.6% vs. 69.5% ± 11.0%). Likewise, although LVEF calculated using QGS significantly differed between conventional SPECT and IQ•SPECT (75.0 ± 9.6 vs. 79.5 ± 8.3) ( P = 0.0005), LVEF calculated using cardioREPO did not (72.3% ± 9.0% vs. 74.3% ± 8.3%). Conclusion: In small-heart patients, the difference in LVEF between IQ•SPECT and conventional SPECT was less when calculated using cardioREPO than when calculated using QGS. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

  16. Experiencia de familiares de enfermos con cáncer terminal respecto a las decisiones al final de la vida

    Directory of Open Access Journals (Sweden)

    Norma Alicia Ordóñez Vázquez

    2016-01-01

    Full Text Available Introducción: La experiencia de los familiares que toman el rol de cuidadores primarios, en el proceso de una enfermedad terminal como el cáncer, proporciona información acerca de la toma de decisiones al final de la vida. El objetivo de este trabajo fue conocer desde la experiencia del familiar del enfermo quién toma las decisiones al final de la vida y cómo afectan estas decisiones al enfermo si no se considera su autonomía. Método: Tipo de estudio: Investigación de corte cualitativo que parte del paradigma hermenéutico fenomenológico. Se aborda desde la postura fenomenológica porque esta permite conocer la percepción que tienen las personas del mundo en el cual viven y el significado que le dan. Además se centra en la experiencia de vida de las personas, en este caso en la experiencia de los familiares de enfermos terminales. Se utilizó la entrevista semiestructurada. Participantes: Cuidadores primarios y familiares de enfermos con cáncer terminal que fueron atendidos en hospitales de la ciudad de México. Procedimiento: Se elaboró una guía de entrevista semiestructurada. Se realizaron 11 entrevistas de las cuales ocho formaron díadas cuidador/familiar. Las tres restantes se realizaron a cuidadores. Seis entrevistas se llevaron a cabo en un espacio de un hospital de tercer nivel y cinco en espacios públicos. Se utilizó el análisis temático y el método de van Manen. Resultados: La experiencia de los familiares muestra por una parte que las decisiones fueron tomadas por el enfermo (plano autónomo, aunque existieron algunos casos en los que él no tomó la decisión, en el momento final, los familiares fueron los que tuvieron que asumir la responsabilidad de tomar decisiones, dependiendo de cómo se iba presentando el proceso de enfermedad (plano dependiente. Es importante resaltar que en los casos estudiados no siempre existió adecuada comunicación médico-paciente. Además, desde la perspectiva fenomenológica, se

  17. Stress-induced myocardial ischemia is associated with early post-stress left ventricular mechanical dyssynchrony as assessed by phase analysis of {sup 201}Tl gated SPECT myocardial perfusion imaging

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chien-Cheng; Shen, Thau-Yun [Show Chwan Memorial Hospital, Department of Cardiology, Changhua (China); Chang, Ming-Che [Changhua Christian Hospital, Department of Nuclear Medicine, Changhua (China); Hung, Guang-Uei [Chang Bing Show Chwan Memorial Hospital, Department of Nuclear Medicine, Changhua (China); China Medical University, Department of Biomedical Imaging and Radiological Science, Taichung (China); Chen, Wan-Chen [Chang Bing Show Chwan Memorial Hospital, Department of Nuclear Medicine, Changhua (China); Kao, Chia-Hung [China Medical University, Department of Biomedical Imaging and Radiological Science, Taichung (China); Chen, Ji [Emory University School of Medicine, Department of Radiology and Imaging Sciences, Atlanta, GA (United States)

    2012-12-15

    In {sup 201}Tl SPECT myocardial perfusion imaging (MPI) data are acquired shortly after the stress injection to assess early post-stress left ventricle (LV) function. The purpose of this study was to use {sup 201}Tl SPECT MPI to investigate whether stress-induced myocardial ischemia is associated with LV mechanical dyssynchrony. Enrolled in the study were 75 patients who were referred for dipyridamole stress and rest {sup 201}Tl gated SPECT MPI. The early post-stress scan was started 5 min after injection, and followed by the rest scan 4 h later. The patients were divided into three groups: ischemia group (N = 25, summed stress score, SSS, {>=}5, summed rest score, SRS, <5), infarct group (N = 16, SSS {>=}5, SRS {>=}5) and normal group (N = 34, SSS <5, SRS <5). LV dyssynchrony parameters were calculated by phase analysis, and compared between the stress and rest images. In the ischemia group, LV dyssynchrony was significantly larger during stress than during rest. On the contrary, LV dyssynchrony during stress was significantly smaller than during rest in the normal and infarct groups. LV dyssynchrony during rest was significantly larger in the infarct group than in the normal and ischemia groups. There were no significant differences in LV dyssynchrony during rest between the normal and ischemia groups. Stress-induced myocardial ischemia caused dyssynchronous contraction in the ischemic region, leading to a deterioration in LV synchrony. Normal myocardium had more synchronous contraction during stress. The different dyssynchrony pattern between ischemic and normal myocardium early post-stress may aid the diagnosis of coronary artery disease using {sup 201}Tl gated SPECT MPI. (orig.)

  18. Detection of myocardial viability by means of Single Proton Emission Computed Tomography (Perfused SPECT) dual {sup 201} Tl (rest of 15 minutes, 24 late hours and 24 hours reinjection) and gated-SPECT {sup 99m} Tc-SESTAMIBI in effort or stimulation of the coronary reserves; Deteccion de viabilidad miocardica mediante tomografia por emision de foton unico (SPECT perfusorio) dual {sup 201} Talio (Reposo de 15 minutos, 24 horas tardio y 24 horas reinyeccion) y gated-SPECT {sup 99m} Tc-SESTAMIBI en esfuerzo o estimulo de reserva coronaria

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza V, R

    2004-07-01

    The objective of this work was to determine if the images of SPECT {sup 201} TI in rest of 15 minutes, 24 late hours and Gated-SPECT {sup 99m} Tc-SESTAMIBI in effort or stimulation of coronary reservation correlate with the study of 24 hours post reinjection of {sup 201}TI to determine the presence of having knitted viable myocardium. Material and methods: 29 patients were studied with coronary arterial illness (EAC) to who are carried out SPECT {sup 201} TI in rest with images of 15 minutes, 24 late hours and 24 hours reinjection, by means of the administration of {sup 201}TI to dose of 130 MBq and reinjection with 37 MBq. and Gated-SPECT {sup 99m}Tc-SESTAMIBI in effort or stimulation of coronary reservation, later to the administration of 1110 MBq. Results: 29 patients were included according to inclusion approaches and exclusion, of those which 22 (75.86%) they correspond at the masculine sex and 7 (24.13%) to the feminine one, with an average of 62.1 year-old age, 2320 segments myocardial were analysed so much it is phase post-effort as rest; they were diagnosed a total of 264 segments with heart attack, of which viability myocardium was observed in 174 segments. The statistical tests are analysis of frequencies. The non parametric test of Wilcoxon and Mann-Whitney. Conclusions: the viability myocardial at the 24 late hours and 24 hours reinjection was similar; significant difference exists between the study of 15 minutes and 24 hours reinjection, ischemic illness was also demonstrated in territories different to the heart attack area in the studies of 15 minutes, late 24 hours and 24 hours reinjection. (Author)

  19. Feasibility and diagnostic accuracy of Ecg-gated SPECT myocardial perfusion imaging by a two-hour protocol: The Myofast study;Faisabilite et precision diagnostique d'un protocole de scintigraphie myocardique synchronisee a l'ECG en deux heures: l'etude Myofast

    Energy Technology Data Exchange (ETDEWEB)

    Dunet, V.; Costo, S.; Sabatier, R.; Grollier, G.; Bouvard, G.; Agostini, D. [CHU Cote-de-Nacre, Service de medecine nucleaire, 14 - Caen (France)

    2010-04-15

    Aim of the study: To assess the feasibility of early stress and rest myocardial perfusion and function study using a fast {sup 99m}Tc-tetrofosmin gated-SPECT protocol in patients with known coronary artery disease. Materials and methods: Forty-three patients (pts) (37 M, 6 F, mean age 63.8 +- 9.8 years) underwent a {sup 99m}Tc-Tetrofosmin gated-SPECT (Axis Picker-Philips) myocardial study and a coronary angiography (C.A.) within 3 months. Images were acquired (LEHR, eight bins, 40 sec per image) after injection of {sup 99m}Tc-tetrofosmin (200 to 380 MBq) early (15 min) post-stress (36 dipyridamole, two dobutamine and five ergo-metric stress), and at rest after {sup 99m}Tc-tetrofosmin reinjection (600 to 1150 MBq), in a total time not exceeding 2 hours. Processing was performed with Q.G.S. software using the 17-segment model. Pathological study was defined as a summed difference score (SDS) greater than or equal to 4 4, a fixed defect with summed rest score greater than or equal to 4 and/or L.V. dysfunction defined as myocardial stunning (variation between stress and rest L.V.E.F. greater than or equal to 4 5%), stress L.V.E.F. less than or equal to 45% or rest L.V.E.F. less than or equal to 40%. Results were compared with C.A., and stenosis greater than or equal to 4 50% was considered as significant. Results: For 100% the quality of SPECT imaging was good or excellent. For six patients gating was impossible because of arrhythmia. The overall sensitivity, specificity and accuracy were 95%, 50%, and 91%, respectively. The concordance between gated SPECT and C.A. was moderate (kappa = 0.45, S.E. = 0.15). Interestingly, early-gated acquisition permitted to underline left ventricular dysfunction in 11 cases (30%), of whom eight had poly vascular disease. Stunning was detected in six of 37 cases (16%), of whom six had poly vascular disease. Conclusion: A one-day two-hour {sup 99m}Tc-tetrofosmin gated-SPECT protocol to assess left ventricular perfusion and function is

  20. Evaluation of exercise-induced myocardial stunning by means of immediate post-exercise Tc-99m sestamibi gated SPECT

    International Nuclear Information System (INIS)

    Ouvrier, M.J.; Hitzel, A.; Vera, P.; Manrique, A.; Bernard, M.; Manrique, A.

    2009-01-01

    Aim: Repeated episodes of myocardial stunning may lead to chronic ventricular dysfunction. We attempted to assess the parameters related to post-exercise stunning in patients undergoing gated SPECT. Methods: Six hundred patients undergoing a one-day stress/rest 99m Tc-sestamibi gated SPECT were studied. Stress imaging was acquired within 15 minutes after injection. Summed perfusion scores (S.S.S., S.R.S. and S.D.S.) were calculated using Q.P.S., and L.V. function assessed using Q.G.S.. Stunning was defined as the association of ischemia (S.S.S. = 4 and SDS > 0) and a minimum of 5% decrease in post-stress E.F.. Results: Ischemia was found in 225 (37.5%) patients. Among these, 67 (30%) showed myocardial stunning. Patients with stunning had a lower rest E.S.V. (47 ± 24 ml vs 65 ± 52 ml, p < 0.0003) and E.D.V. (108± 35 ml vs 122 ± 66 ml, p 0.03), an increased rest L.V.E.F. (58 ± 10% vs 52 ± 13%, p < 0.0001) and a decreased post-stress L.V.E.F. (49 ± 10% vs 53 ± 13%, p < 0.02) compared to patients with no stunning. The number of myocardial segments showing reversible perfusion defects was increased in patients with stunning (2.7 ± 2.6 vs 1.7 ± 2.1, p < 0.02). On logistic regression, an extent of ischemia greater than two segments and a rest E.F. greater than 45% were independent predictors of the occurrence of myocardial stunning in patients with ischemia. Conclusions: In patients with ischemia, exercise-induced stunning was associated with an increased extent of ischemia but also preserved rest ventricular function. (authors)

  1. Una experiencia de aprendizaje con etiquetado social || A learning experience based on social tagging

    Directory of Open Access Journals (Sweden)

    Francisco José Santos-Caamaño

    2015-11-01

    Full Text Available Se exponen aquí los resultados de una experiencia educativa mediada con TIC donde jugó un papel relevante el empleo del etiquetado social o conjuntos de etiquetas creadas por múltiples usuarios en espacios web 2.0. Estas sirvieron para enunciar contenidos textuales disponibles en red, y han resultado especialmente útiles para su empleo en el aula en tres estrategias de aprendizaje: en el ordenamiento taxonómico y categorización de contenidos trabajados en clase, en su capacidad de destacar sintéticamente conceptos clave y en la facilitación al alumno de un medio sencillo para la expresión de su subjetividad y actitudes ante los materiales trabajados.

  2. Experiencia de trabajo interdisciplinario en alfabetización básica con mujeres, promoción de su salud y derechos.

    OpenAIRE

    Sanabría Hernández, Marcela; Castro Carmiol, Evelyn; Sanabría Hernández, Gabriela

    2015-01-01

    El artículo presenta una experiencia de trabajo interinstitucional e interdisciplinaria, entre la Caja Costarricense de Seguro Social- Área de Salud Goicoechea 2, Servicio de Trabajo Social con la Universidad Estatal a Distancia, Cátedra de Psicopedagogía, realizada en el Área de Salud Goicoechea 2, referente a la alfabetización básica con mujeres adultas, vecinas de los cantones de Moravia y Goicoechea, San José, Costa Rica. El proceso se llevó a cabo a partir de una metodología grupal socio...

  3. La experiencia de mujeres con discapacidades en los proyectos archivísticos del siglo XXI

    Directory of Open Access Journals (Sweden)

    Dora Inés Munévar M.

    2011-09-01

    Full Text Available El artículo analiza la manera como los proyectos archivísticos del siglo XXI podrían favorecer la reconstituciónde subjetividades silenciadas y develar historias de exclusión. Se toma como caso de análisis ladocumentación sobre mujeres con discapacidades en instituciones de rehabilitación, salud mental oprotección legal. A partir de allí, la autora propone mecanismos para que la información depositadaen los archivos, especialmente institucionales, contribuya a la recuperación de la memoria, y a la democratizacióny descolonización de la historia de grupos excluidos y marginados. Esto gracias a que losarchivos albergan no solo documentos escritos autorizados sino una multiplicidad de materiales oralesy visuales.Materiales que pueden contribuir a la visibilización y reconocimiento de la diferencia, desdelas experiencias vidas de, por ejemplo, las mujeres con discapacidades, quienes adquirirían así una vozpropia.

  4. Experiencia con la fístula arteriovenosa interna para hemodiálisis periódica

    Directory of Open Access Journals (Sweden)

    Andrés Rebollo

    1971-04-01

    Full Text Available Dos y medio años después de experiencia con 600 diálisis en 8 pacientes han demostrado que el uso de fístula anteriovenosa descrita por brescia es en el momento el mejor método para el acceso repetido a los vasos sanquíneos durante el tratamiento de la hemodiálisis periódica suprimiendo algunos de los inconvenientes a la cánula externa de teflón y sylastic, trombosis, embolismo pulmonar y septicemia son complicaciones previsibles en si mayor parte y debidas a fallas, mal manejo y omiciones de asepsia elemental durante las punciones.

  5. Experiencias formativas de uso didáctico de la realidad aumentada con alumnado del grado de educación primaria en la Universidad de Málaga

    OpenAIRE

    Moreno Martínez, Noelia Margarita; Leiva Olivencia, Juan José

    2017-01-01

    El presente estudio describe experiencias innovadoras universitarias orientadas hacia la formación en el uso didáctico de la realidad aumentada de dos grupos de estudiantes del Grado de Educación Primaria de la Universidad de Málaga. Dichas experiencias se han desarrollado con 105 estudiantes a través de seminarios formativos de dos horas en las asignaturas de Didáctica General y Didáctica de las Ciencias Sociales durante el curso académico 2015...

  6. Gated-SPECT myocardial scintigraphy in left bundle branch block: A study in patients with and without coronary artery disease

    International Nuclear Information System (INIS)

    Falcao, A.M.; Moffa, P.J.; Chalela, W.A.; Soares, J.; Oliveira, C.G.; Kreling, J.C.; Ferreira, B.A.; Uchida, A.H.; Meneghetti, J.C.

    2002-01-01

    Introduction: Myocardial perfusion scintigraphy (MPS) is a non-invasive method helpful for evaluating coronary heart disease. In left bundle branch block (LBBB), the myocardial scintigraphy frequently reveals septal abnormalities in the absence of coronary artery disease (CAD) and gives rise to 'false-positive' results in patients (pts) with suspected CAD. The purpose of this study was to assess the diagnostic role of ECG-gated SPECT in pts with complete LBBB, with and without known CAD. Methods. This study included 46 pts, 29 women (63%), with mean age 63.8 ± 11.6yr, divided into two groups: Group 1 (n=21 pts) with LBBB and CAD angiographically confirmed and Group 2 (n=25 pts) with LBBB and normal coronangiography. All pts underwent MPS at rest and two stress tests - dipyridamole (DIP) and treadmill exercise test (ET) with Bruce protocol. Myocardial perfusion, wall motility and wall thickening were analyzed qualitatively by consensus of two observers in anterior, septal, inferior, lateral and apical myocardial segments. Scores were attributed to: perfusion as normal, reversible or fixed defects; motility as normal, hypokinesia, akinesia or dyskinesia and thickening if present or absent. The left ventricle ejection fraction (LVEF) was automatically calculated from the ECG-gated SPECT. Results: The comparative analysis between groups 1 and 2 for both stresses (DIP and ET) for the parameters analyzed in the myocardial segments are presented: LVEF at rest, ET and DIP show statistically significant differences between groups 1 and 2 (p<0.0001). Conclusion: In the anterior and septal segments, only septal thickening was capable of differentiating between LBBB with and without CAD, independent of the kind of stress. In the other segments there was no influence of disturbance conduction for the perfusion analysis

  7. Trasplante renal con HLA idéntico de donante vivo y cadavérico: experiencia de la Fundación Valle de Lili, Cali, Colombia

    OpenAIRE

    Caicedo, Luis Armando; Gómez-Vega, Juan Carlos; Duque, Mauricio Francisco; Serrano, Óscar Javier; Manzi, Eliana; Arrunátegui, Ana María; Posada, Juan Guillermo; Mesa, Liliana; Schweineberg, Johanna; Durán, Carlos Eduardo; Villegas, Jorge Iván; Dávalos, Diana María; Echeverri, Gabriel Jaime

    2016-01-01

    Introducción: En el trasplante renal con HLA idéntico los episodios de rechazo agudo son menores y tienen mejores tasas de supervivencia del injerto, comparado con los receptores con HLA no idéntico; a pesar de esto, persiste el dilema en cuanto al retiro o la disminución de la dosis de inmunosupresión. El objetivo de este trabajo es describir la experiencia de los trasplantes renales con HLA idéntico de donante vivo y cadavérico que se han realizado en la Fundación Valle del Lili desde 1995 ...

  8. Necesidades afectivo-sexuales en personas con discapacidad intelectual intelectual. Claves para construir propuestas formativas desde la experiencia subjetiva

    OpenAIRE

    Rojas Pernía, Susana; Haya Salmón, Ignacio; Lázaro Visa, Susana

    2015-01-01

    Resumen: El objetivo de este trabajo es presentar las necesidades vividas por un grupo de personas con discapacidad intelectual en torno a la esfera afectiva y sexual. Para ello, a través de una entrevista semiestructurada que abarca diferentes áreas vitales, 16 entrevistados ponen de relieve sus conocimientos y experiencias en torno a la relación de pareja y la intimidad. Sus relatos codificados muestran tres grandes necesidades ilustradas a lo largo del texto: la búsqueda del otro próximo c...

  9. Caracterización de los niveles de empatía en médicos con experiencia en medicina alternativa en Bogotá

    Directory of Open Access Journals (Sweden)

    Sergio Hernández Vela

    2014-07-01

    Full Text Available Antecedentes. En la relación médico paciente la empatía es esencial para constituir una buena práctica clínica, ya que valora la capacidad de ponerse en el lugar del otro y por lo tanto permite comprender la situación de adversidad del paciente y actuar  acorde con las circunstancias.   En el caso de la medicina alternativa esta capacidad hace parte de los fundamentos epistemológicos que sustentan las diferentes áreas de énfasis.  Objetivo. Caracterizar el nivel de empatía de los médicos con experiencia en medicina alternativa en las áreas de Homeopatía, Medicina Tradicional China y Acupuntura, Terapia Neural y Osteopatía.  Materiales y métodos. Estudio  descriptivo correlacional realizado en el periodo entre Julio y Enero de 2013, mediante el diligenciamiento de una encuesta estructurada con la Escala de Empatía Médica de Jefferson (JSPE, adaptada para la población. Posteriormente se categorización y correlacionaron los puntajes de empatía obtenidos con las variables sociodemográficas expresando los resultados en frecuencias y promedios con sus respectivos intervalos de confianza.  Resultados. El puntaje general de empatía en los médicos con experiencia en medicina alternativa que participaron en el estudio fue en promedio de 124,81, con un rango entre 94-140, una mediana de 127 y DS de 9,93, observándose mayor frecuencia y puntaje en individuos de género femenino, sin diferencia estadísticamente significativa respecto de la población masculina.  Conclusiones. Los niveles de empatía en los médicos con formación en medicina alternativa son similares a los registrados en médicos especializados en psiquiatría, medicina familiar, medicina interna y pediatría, quienes registran los mejores estándares empáticos para la relación médico paciente.

  10. Vivenciando la experiencia de jóvenes con violencia familiar que viven en Hogares protegidos

    Directory of Open Access Journals (Sweden)

    María Julia Calvo-Gil

    Full Text Available El móvil del estudio de las vivencias de jóvenes con maltrato nace al identificar y establecer contacto con víctimas. Otro motivo del fenómeno fue que, no obstante ser un tema de diversas investigaciones y con el que convive día a día nuestra sociedad, es ineficiente el compromiso que adquiere cada ser social con esta problemática. El objetivo de la investigación fue comprender sus vivencias, sus experiencias de vida, cómo ellos perciben las causas que genera la situación y cómo la afrontan, para así ampliar la visión en la atención integral que realiza el profesional de Enfermería al identificar un caso de maltrato. Para el trabajo se utilizó la metodología cualitativa con enfoque fenomenológico, lo cual permitió obtener conocimientos sobre el fenómeno en estudio, lo que se logró a través del análisis de discursos obtenidos de forma voluntaria de jóvenes pertenecientes a un Hogar del Servicio Nacional de Menores (SENAME, Chile, a los cuales se les dio la confidencialidad en el manejo de información y de su identidad. Del análisis de los datos se obtuvieron los siguientes temas: Describiendo sentimientos de abandono; Negándose a asumir la situación de maltrato; Percibiendo el apoyo familiar; Postergando sus necesidades; Expresando rebeldía.

  11. ¿Aprender tsotsil? Experiencia con niños de una primaria urbana en San Cristóbal

    Directory of Open Access Journals (Sweden)

    Alejandra Rodríguez Torres

    2014-01-01

    Full Text Available San Cristóbal es una ciudad donde convergen varias culturas, situación que presenta un reto a la enseñanza y a la convivencia escolar. Este trabajo se basa en una experiencia con niños de familias migrantes del estado de Chiapas, México, de cuarto año de primaria. El propósito inicial consistió en fomentar el respeto a la diversidad cultural a través de la lectoescritura en tsotsil y español. Para profundizar en la percepción de los niños sobre la adquisición de la lectoescritura en tsotsil y los valores se trata de analizar lo que ellos mismos han escrito. Contamos para esta aproximación con las cartas dirigidas a la persona encargada del apoyo financiero en las cuales los alumnos nos dan a conocer su opinión sobre los talleres impartidos, y con una serie de cuentos escritos libremente por ellos mismos en donde se reflejan sus valores e intereses.

  12. Una experiencia de educación ambiental con estudiantes de un colegio rural de Costa Rica

    Directory of Open Access Journals (Sweden)

    Pablo Sisfontes-Guilarte

    2010-10-01

    Full Text Available Recibido 05 de abril de 2010 • Aceptado 24 de junio de 2010 • Corregido 28 de julio de 2010   Este artículo describe una experiencia pedagógica de Educación Ambiental desarrollada en un colegio rural de Costa Rica con estudiantes de IX año, caracterizada por la dinámica de taller, en la cual destaca la participación en la construcción de iniciativas para enfrentar la problemática ambiental detectada por los jóvenes en sus respectivas comunidades. El artículo persigue contribuir con la construcción de un modelo pedagógico autogestionario de capacitación y formación de jóvenes en los sectores ambientales, turísticos y agrícolas, desde la convicción de que la educación se constituye en una alternativa indispensable para la comprensión y solución de la problemática ambiental.

  13. APRENDIENDO CON LAS TIC: UNA EXPERIENCIA UNIVERSITARIA (LEARNING FROM THE ICTS: A UNIVERSITY EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Regueyra Edelman María Gabriela

    2011-06-01

    Full Text Available Resumen:Se comparte en este artículo la experiencia del uso de las TIC en dos cursos que se imparten en la carrera de Trabajo Social de la Universidad de Costa Rica. Se detallan los recursos tecnológicos utilizados y el uso que se da a cada uno: Facebook, Blogger, Moodle, correo electrónico, se complementa la experiencia con la incorporación de las opiniones de la población estudiantil matriculada en los cursos y destacando los retos que el uso de las TIC presenta a la población docentes en particular y a la Universidad de Costa Rica en general. El artículo retoma discusión de la Sociedad del Conocimiento y la Información, y las TIC como procesos que han transformado la sociedad actual, con su incorporación tanto en el campo económico, social y laboral como en los ámbitos educativo, familiar y personal, lo que ha generado nuevas interacciones sociales y una brecha entre la población que tiene acceso a la tecnología y la que no lo tiene, situación que ha impactado fundamentalmente el ámbito educativo, donde se han ido incorporando las TIC de manera progresiva, con algunas reservas tanto de la población docente como de la población estudiantil.Abstract: This article deals with the experience of using the Information and Communication Technologies (ICTs for two courses in the Social Work Major at the University of Costa Rica. The use of technological resources such as Facebook, Blogger, Moodle and e-mail are described. The usability of this experience is complemented with opinions from students who registered in those courses, by highlighting the challenges encountered by faculty in particular and by the University of Costa Rica in general, regarding the implementation of ICTs. This article recognizes that the Community and Information-Based Knowledge and the ICTs are means for the transformation of the community itself as they are introduced in the economic, social, labor, family, personal and educational fields. Although the

  14. Asymmetrically thickened posterior wall is associated with decline of ejection fraction after stress on adenosine stress/rest thallium-201 gated myocardial SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bom Sahn; Lee, Won Woo; Lee, Dong Soo; Chung, June Key; Lee, Myung Chul; Kim, Sang Eun [College of Medicine, Seoul National University, Seoul (Korea, Republic of)

    2004-07-01

    LV parameters (LVEF. ESVI and EDVI) on adenosine stress/rest thallium-201 gated myocardial SPECT (gSPECT) are various from stress to rest. We investigated the reason why they were various in patients without coronary artery disease. Seventy-one patients(M:F=32:39, age 58.1{+-}9.7yrs), who underwent gSPECT and coronary angiography (CAG) due to chest pain or preoperative evaluation were included. CAG results were normal or insignificant. Exclusion criteria were atrial fibrillation, thyroid disease, primary cardiomyopathy, myocardial bridge, LBBB, MI, and valvular heart disease. Patients were calssified into 3 groups by EF difference ({delta}EF=rest-stress EF) on gSPECT : group1 ({delta}EF{>=}10), group2 (0 {<=}{delta}EF<10), and group3 ({delta}EF<0). LV parameters on gSPECT and thicknesses of IVS (interventricular septum) and LVPW (left ventricular posterior wall) on echocardiography were compared among the 3 groups. Myocardial perfusion status were normal or mild reversible/persistent perfusion defect in 76.1% (54/71). LVEFs at stress were not different among all 3 groups : 59.3{+-}8.54% in group 1 (61.3{+-}10.22% in group 2 and 64.8{+-}7.58% in group 3 (p>0.05). But LVEF at rest was smaller in group 3 (58.7{+-}8.38%) than the other groups (72.5{+-}8.77% in group1 and 66.7{+-}10.6% in group2) (p<0.01). EDVIs and ESVI at stress were larger than those at rest in all groups (p<0.05) except ESVI in group 3 (16.2{+-}6.21ml at stress and 17.5{+-}6.41ml at rest, p<0.01), and that was attributed to EF<0 in group 3. In echocardiographical analysis, group 3 had significantly increased wall thickness of LVPW (10.7{+-}1.2mm versus 9.4{+-}1.6mm, p=0.01) and decreased wall thickness ratio of IVS/LVPW (0.963{+-}0.102 versus 1.048{+-}0.104, p=0.035) than group 1. In patients without coronary artery disease, LVEF, EDVI and ESVI on gSPECT were various and decline of LVEF from stress to rest was caused by unnormalized ESVI . Asymmetrically thickened LVPW may play a crucial role and

  15. La intimidad y la experiencia en lo público

    Directory of Open Access Journals (Sweden)

    María Teresa Luna

    2007-05-01

    Full Text Available Esta investigación, de corte fenomenológico, se posiciona en los postulados de la fenomenología del mundo social desarrollada por Alfred Schütz; en este sentido se discute la categoría intimidad como experiencia subjetiva en la que se vivencia la configuración del yo y el tú, y en la que se producen y decantan significaciones esenciales para la relación con uno mismo o con una misma, y con los otros u otras, lo cual parece producir esquemas de actuación en lo público, entendido como el espacio físico y simbólico compartido con otros mediatos u otras mediatas. La información fue construida mediante entrevistas conversacionales en las que cuatro profesionales (tres mujeres y un hombre, vinculados a Organizaciones No Gubernamentales de la ciudad de Medellín con un fuerte trabajo en lo público, construyeron narrativas autobiográficas. La unidad de lectura de la información fue el relato –entendido como una historia con un principio, un desarrollo y un final–y el criterio de selección de relatos significativos fue el acontecimiento biográfico, entendido como un evento que produce un quiebre en la propia biografía, sea porque rompe algo o inaugura algo. Los acontecimientos seleccionados fueron aquellos que aportaban información pertinente para comprender la progresiva configuración de la experiencia íntima y su encadenamiento con una cierta forma de experienciar la actuación en lo público. Los resultados muestran que la intimidad es experiencia de posicionamiento en asuntos morales que están en la base de la actuación en lo público, así como también que en las relaciones íntimas –básicamente con los contemporáneos inmediatos como los amigos, las amigas y las parejas– se construyen experiencias como la confianza, el cuidado y el respeto, que son determinantes en la manera de transitar por la esfera pública.

  16. La intimidad y la experiencia en lo público

    Directory of Open Access Journals (Sweden)

    María Teresa Luna C.

    2007-01-01

    Full Text Available Esta investigación, de corte fenomenológico, se posiciona en los postulados de la fenomenología del mundo social desarrollada por Alfred Schütz; en este sentido se discute la categoría intimidad como experiencia subjetiva en la que se vivencia la configuración del yo y el tú, y en la que se producen y decantan significaciones esenciales para la relación con uno mismo o con una misma, y con los otros u otras, lo cual parece producir esquemas de actuación en lo público, entendido como el espacio físico y simbólico compartido con otros mediatos u otras mediatas. La información fue construida mediante entrevistas conversacionales en las que cuatro profesionales (tres mujeres y un hombre, vinculados a Organizaciones No Gubernamentales de la ciudad de Medellín con un fuerte trabajo en lo público, construyeron narrativas autobiográficas. La unidad de lectura de la información fue el relato –entendido como una historia con un principio, un desarrollo y un final–y el criterio de selección de relatos significativos fue el acontecimiento biográfico, entendido como un evento que produce un quiebre en la propia biografía, sea porque rompe algo o inaugura algo. Los acontecimientos seleccionados fueron aquellos que aportaban información pertinente para comprender la progresiva configuración de la experiencia íntima y su encadenamiento con una cierta forma de experienciar la actuación en lo público. Los resultados muestran que la intimidad es experiencia de posicionamiento en asuntos morales que están en la base de la actuación en lo público, así como también que en las relaciones íntimas –básicamente con los contemporáneos inmediatos como los amigos, las amigas y las parejas– se construyen experiencias como la confianza, el cuidado y el respeto, que son determinantes en la manera de transitar por la esfera pública.

  17. Esclerosis múltiple. : nuestra experiencia

    OpenAIRE

    Houlne, M.; Zalazar, M.; Sagaz, A.; López Laur, José Daniel

    2006-01-01

    Objetivos: analizar la experiencia obtenida y evaluar los resultados urodinámicos del estudio de 18 pacientes con esclerosis múltiple. Material y Métodos: se estudiaron 18 casos, valorándose la historia clínica, ecografía vesical y renal, analizándolos urodinámicamente con uroflujometría, residuo post miccional (RPM), cistotonometría y electromiografía esfinteriana. Urocultivo y antibiograma de orina. Resultados: del análisis de toda...

  18. Pensar la experiencia mística desde la epistemología

    Directory of Open Access Journals (Sweden)

    Lina Marcela Cadavid Ramírez

    2016-06-01

    Full Text Available Con la crisis del paradigma newtoniano a principios del siglo XX, vemos surgir un acercamiento entre la ciencia, la religión y el misticismo, alentado por algunos de los físicos cuánticos más destacados, asimismo, la epistemología se vio afectada y a lo largo del siglo XX se entabló una discusión en torno a la objetividad del conocimiento y la construcción socio-lingüística de la realidad. Con este trasfondo, la experiencia mística será objeto de estudio por la epistemología, que desde una perspectiva constructivista afirmará el carácter mediado de este tipo de experiencias. Sin embargo, una revisión de esta postura muestra que es necesario conceder un carácter singular a la experiencia mística, que a su vez permite una comprensión renovada de la experiencia mística.

  19. Automatic construction of 3D-ASM intensity models by simulating image acquisition: application to myocardial gated SPECT studies.

    Science.gov (United States)

    Tobon-Gomez, Catalina; Butakoff, Constantine; Aguade, Santiago; Sukno, Federico; Moragas, Gloria; Frangi, Alejandro F

    2008-11-01

    Active shape models bear a great promise for model-based medical image analysis. Their practical use, though, is undermined due to the need to train such models on large image databases. Automatic building of point distribution models (PDMs) has been successfully addressed and a number of autolandmarking techniques are currently available. However, the need for strategies to automatically build intensity models around each landmark has been largely overlooked in the literature. This work demonstrates the potential of creating intensity models automatically by simulating image generation. We show that it is possible to reuse a 3D PDM built from computed tomography (CT) to segment gated single photon emission computed tomography (gSPECT) studies. Training is performed on a realistic virtual population where image acquisition and formation have been modeled using the SIMIND Monte Carlo simulator and ASPIRE image reconstruction software, respectively. The dataset comprised 208 digital phantoms (4D-NCAT) and 20 clinical studies. The evaluation is accomplished by comparing point-to-surface and volume errors against a proper gold standard. Results show that gSPECT studies can be successfully segmented by models trained under this scheme with subvoxel accuracy. The accuracy in estimated LV function parameters, such as end diastolic volume, end systolic volume, and ejection fraction, ranged from 90.0% to 94.5% for the virtual population and from 87.0% to 89.5% for the clinical population.

  20. GATE simulation of a new design of pinhole SPECT system for small animal brain imaging

    International Nuclear Information System (INIS)

    Ozsahin, D. Uzun; Bläckberg, L.; Fakhri, G. El; Sabet, H.

    2017-01-01

    Small animal SPECT imaging has gained an increased interest over the past decade since it is an excellent tool for developing new drugs and tracers. Therefore, there is a huge effort on the development of cost-effective SPECT detectors with high capabilities. The aim of this study is to simulate the performance characteristics of new designs for a cost effective, stationary SPECT system dedicated to small animal imaging with a focus on mice brain. The conceptual design of this SPECT system platform, Stationary Small Animal SSA-SPECT, is to use many pixelated CsI:TI detector modules with 0.4 mm × 0.4 mm pixels in order to achieve excellent intrinsic detector resolution where each module is backed by a single pinhole collimator with 0.3 mm hole diameter. In this work, we present the simulation results of four variations of the SSA-SPECT platform where the number of detector modules and FOV size is varied while keeping the detector size and collimator hole size constant. Using the NEMA NU-4 protocol, we performed spatial resolution, sensitivity, image quality simulations followed by a Derenzo-like phantom evaluation. The results suggest that all four SSA-SPECT systems can provide better than 0.063% system sensitivity and < 1.5 mm FWHM spatial resolution without resolution recovery or other correction techniques. Specifically, SSA-SPECT-1 showed a system sensitivity of 0.09% in combination with 1.1 mm FWHM spatial resolution.

  1. La Narración oral: Alternativa para el desarrollo de una experiencia educativa con perspectivas de género

    Directory of Open Access Journals (Sweden)

    Marianela Rosa Peña Lora

    2015-01-01

    Full Text Available El trabajo que se presenta explica el carácter de la experiencia pedagógica realizada en la Universidad de Ciencias Médicas de Santiago de Cuba, referida a la creación de una Cátedra de Oralidad con enfoque de género, que tiene como objetivo contribuir a la gestión y desarrollo de prácticas y procesos sociales de carácter educativo/comunicacional y a los procesos formativos que de ello se derivan, así como desarrollar una reflexión crítica sobre el papel de la mujer en la experiencia narrativa de la vida cotidiana y en el rescate de la palabra en diferentes contextos educativos y socioculturales. En la implementación de la cátedra, organizada en áreas de desarrollo: "Historia de la Universidad de Ciencias Médicas"; "La narrativa oral y la relación interdisciplinaria"; "La medicina narrativa"; "La narración oral como arte y conducta ex-presivo-comunicativa", la transversali-dad del enfoque de género aparece como una estrategia metodológica que desde un planteamiento sistémico vislumbra todo el proceso educativo que posibilita el desarrollo de las habilidades básicas del pensamiento y comunicación basadas en la narración oral. En las conclusiones se expresa cómo el logro de estos objetivos ha transcurrido por un conjunto de actividades en las esferas de la docencia, investigación y extensión, donde además de abordar los aspectos teóricos, se ha realizado una reflexión compartida como construcción y experiencia sociocultural que permitió un intercambio de saberes, experiencias y participación a través de la narración oral, la cual se ha proyectado como espacio abierto para el aprendizaje, experiencia esencialmente humana y estrategia para la investigación.

  2. Mi experiencia en COMISEDH - Comisión de Derechos Humanos

    OpenAIRE

    Leal Lillo, María

    2017-01-01

    Treball final de Màster Universitari en Cooperació al Desenvolupament (Pla de 2015). Codi: SRP531. Curs acadèmic 2016-2017 En este trabajo se presenta la experiencia de prácticas externas del Máster en Cooperación al Desarrollo de la Universidad Jaume I, llevada a cabo en COMISEDH-Comisión de Derechos Humanos, una asociación civil sin ánimo de lucro con 38 años de experiencia en la lucha por los derechos humanos en Perú. A lo largo de los distintos apartados se presenta la entidad y el con...

  3. Role of myocardial perfusion SPECT in asymptomatic diabetic patients

    International Nuclear Information System (INIS)

    Cho, I.; Chun, K.; Won, K.; Lee, H.; Park, J.; Shin, D.; Kim, Y.; Shim, B.; Lee, J.

    2002-01-01

    Purpose: It is important that early diagnosis and treatment of coronary artery disease in diabetic patients, but there are few reports on the prevalence of stress-induced myocardial perfusion abnormalities and the rates of cardiac event in patients with type 2 diabetes. We evaluated the scan findings on gated myocardial perfusion SPECT in asymptomatic diabetic patients. Methods: We performed pharmacological stress test and gated perfusion SPECT in 69 diabetic patients without cardiovascular symptom (mean age: 65 year, male 31 and female 38). Patients underwent two-day imaging protocol and stress study was performed injection of Tc-99m MIBI during adenosine infusion. We followed up these patients by reviewing medical records. Results: Fifty-two of 69 patients (74.5%) showed normal scan findings and 17 patients (24.6%) showed reversible or fixed perfusion defects. Three of 52 patients with normal scan findings showed decreased LV ejection fraction and decreased wall motion. Twenty-three patients with normal scan findings were possible to follow up for more than 1yr (mean time: 18.3±3.3 mo.) and they all had no cardiac event. Three patients with reversible perfusion defects were performed coronary angioplasty. Conclusion: Myocardial perfusion SPECT is a noninvasive method and maybe useful in early diagnosis and predicting prognosis in diabetic patients

  4. Colaboración atención primaria-salud mental en la asistencia a pacientes con depresión: evaluación de una experiencia piloto

    OpenAIRE

    Carlos Calderón; Laura Balagué; Álvaro Iruin; Ander Retolaza; Jon Belaunzaran; Javier Basterrechea; Isabel Mosquera

    2016-01-01

    Objetivo: Implementar y evaluar una experiencia colaborativa entre Atención Primaria (AP) y Salud Mental (SM) para mejorar la asistencia a los pacientes con depresión. Diseño: Proyecto colaborativo piloto con enfoque de investigación acción participativa (IAP) durante 2013. Emplazamiento: : País Vasco. Osakidetza (Servicio Vasco de Salud). Bizkaia y Gipuzkoa. Participantes: Doscientos siete profesionales de medicina de familia, enfermería, psiquiatría, enfermería psiquiátrica, psicol...

  5. Necesidades afectivo-sexuales en personas con discapacidad intelectual. Claves para construir propuestas formativas desde la experiencia subjetiva

    Directory of Open Access Journals (Sweden)

    Susana Rojas Pernia

    2015-12-01

    Full Text Available El objetivo de este trabajo es presentar las necesidades vividas por un grupo de personas con discapacidad intelectual en torno a la esfera afectiva y sexual. Para ello, a través de una entrevista semiestructurada que abarca diferentes áreas vitales, 16 entrevistados ponen de relieve sus conocimientos y experiencias en torno a la relación de pareja y la intimidad. Sus relatos codificados muestran tres grandes necesidades ilustradas a lo largo del texto: la búsqueda del otro próximo con quien compartir su intimidad emocional y afectiva, la necesidad de ampliar sus conocimientos sobre sexualidad a cuestiones de carácter interpersonal y relacional, y la necesidad de contar con espacios de comunicación donde poder intercambiar dudas, buscar apoyos necesarios. El análisis realizado sugiere una revisión de la educación afectiva y sexual dirigida hacia este colectivo, fundamentada casi siempre en la prevención de riesgos, para poner de relieve la importancia de construir propuestas formativas a partir de sus intereses y dudas, que reconozcan también el derecho a vivir su sexualidad e intimidad de forma satisfactoria.

  6. Lectura crítica: tres experiencias venezolanas

    Directory of Open Access Journals (Sweden)

    Adolfo Herrera E.

    2015-01-01

    Full Text Available Las tres experiencias seleccionadas tienen que ver con la difusión de mensajes, lo que las introduce en un mecanismo de amplio espectro informativo, y esto podría llamarse el ingrediente popular.

  7. Amplitude-based data selection for optimal retrospective reconstruction in micro-SPECT

    Science.gov (United States)

    Breuilly, M.; Malandain, G.; Guglielmi, J.; Marsault, R.; Pourcher, T.; Franken, P. R.; Darcourt, J.

    2013-04-01

    Respiratory motion can blur the tomographic reconstruction of positron emission tomography or single-photon emission computed tomography (SPECT) images, which subsequently impair quantitative measurements, e.g. in the upper abdomen area. Respiratory signal phase-based gated reconstruction addresses this problem, but deteriorates the signal-to-noise ratio (SNR) and other intensity-based quality measures. This paper proposes a 3D reconstruction method dedicated to micro-SPECT imaging of mice. From a 4D acquisition, the phase images exhibiting motion are identified and the associated list-mode data are discarded, which enables the reconstruction of a 3D image without respiratory artefacts. The proposed method allows a motion-free reconstruction exhibiting both satisfactory count statistics and accuracy of measures. With respect to standard 3D reconstruction (non-gated 3D reconstruction) without breathing motion correction, an increase of 14.6% of the mean standardized uptake value has been observed, while, with respect to a gated 4D reconstruction, up to 60% less noise and an increase of up to 124% of the SNR have been demonstrated.

  8. Relación entre estrés laboral, alucinación y experiencias anómalas entre profesionales de enfermería

    Directory of Open Access Journals (Sweden)

    Alejandro Enrique-Parra,

    2016-12-01

    Full Text Available Objetivo: evaluar el tipo y frecuencia de experiencias perceptuales inusuales en ámbitos hospitalarios, así como su relación con el estrés laboral y la absorción, y comparar tales experiencias en enfermeros (os que las han tenido. Materiales y Métodos: se analizó una muestra de 39 enfermeros (as con tales experiencias y un grupo control de 61 profesionales (sin experiencias. Las enfermeros (as completaron cuatro instrumentos: la Encuesta de Experiencias Anómalo/Paranormales en Enfermeras y Trabajadores de la Salud, el Maslach Burnout Inventory que mide el estrés laboral, el Cuestionario de Experiencias Alucinatorias que evalúa la propensión a la alucinación y la Escala de Absorción de Tellegen que evalúa el grado de involucramiento en la percepción. Resultados: los profesionales que reportaron tales experiencias no tendían a experimentar mayor estrés laboral, en comparación con un grupo control, en contra de la principal hipótesis; sin embargo, mostraron mayor frecuencia experiencias perceptivas anómalas asociadas a la capacidad de absorción psicológica, que resultó el principal predictor entre enfermeras con experiencia y el grupo control [β= 0,33, p= 0,005; R2= 0,12] combinando estrés laboral y propensión a la alucinación. Conclusión: el análisis estadístico confirma que los profesionales de enfermería que reportan experiencias perceptuales inusuales, tienden a mostrar mayor absorción psicológica, de igual forma, mayor propensión a alucinar; sin embargo, ninguna de estas variables se relaciona con el estrés laboral. El turno de noche es el más propenso a estas experiencias.

  9. Prognostic significance of stress myocardial gated SPECT among Japanese patients referred for coronary angiography: A study of data from the J-ACCESS database

    Energy Technology Data Exchange (ETDEWEB)

    Momose, Mitsuru [Tokyo Women' s Medical University, Department of Radiology, Tokyo (Japan); Nakajima, Kenichi [Kanazawa University Hospital, Department of Nuclear Medicine, Kanazawa (Japan); Nishimura, Tsunehiko [Kyoto Prefectural University of Medicine, Department of Radiology, Graduate School of Medical Science, Kyoto (Japan)

    2009-08-15

    The J-ACCESS [Japanese investigation of prognosis based on gated single photon emission computed tomography (SPECT)] study found that quantitative gated myocardial SPECT (QGS) is valuable for predicting the prognosis of Japanese patients with known or suspected ischaemic heart disease. The present study evaluates the incremental prognostic value of myocardial perfusion imaging (MPI) with QGS among patients referred for coronary angiography (CAG). Among 4,031 Japanese patients registered at 117 hospitals for the J-ACCESS study, we selected 1,011 who underwent CAG within 3 months before or after MPI with QGS. Summed stress, rest and difference scores (SSS, SRS and SDS) were generated from myocardial perfusion images using a 20-segment scoring system. Myocardial ischaemia was judged visually. End-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were determined by QGS. Numbers of diseased (> 75% stenosis) coronary vessels (CDV) were assessed by CAG. All patients were followed up for 3 years to determine cardiac events (CE) including cardiac death, non-fatal myocardial infarction and severe heart failure. Univariate and multivariate analyses of prognostic ability included age, cardiac risk factors (hypertension, hyperlipidaemia, diabetes mellitus and prior myocardial infarction), angiographic findings and the QGS parameters as independent variables. Cardiac events occurred more frequently with increasing numbers of coronary vessel lesions (p=0.0016). Cox univariate analysis revealed that diabetes, CDV, SSS, SDS, EDV, ESV and EF were significant predictors (Wald {chi}{sup 2}=5.99, 12.9, 8.39, 9.11, 35.5, 42.1 and 31.1, respectively), whereas multivariate analysis selected only ESV and SDS as significant predictors (Wald {chi}{sup 2}=36.4, 8.4; p = 0.0038, p < 0.001). MPI with QGS, especially with gated functional data, has incremental prognostic value in addition to angiographic findings. MPI with QGS findings predominantly contribute to the

  10. Regional wall thickening in gated myocardial perfusion SPECT in a Japanese population: effect of sex, radiotracer, rotation angles and frame rates

    Energy Technology Data Exchange (ETDEWEB)

    Akhter, Nasima; Nakajima, Kenichi; Okuda, Koichi; Matsuo, Shinro; Yoneyama, Tatsuya; Taki, Junichi; Kinuya, Seigo [Kanazawa University Hospital, Department of Nuclear Medicine, Kanazawa, Ishikawa (Japan)

    2008-09-15

    Gated single-photon emission computed tomography (SPECT) imaging of myocardium by {sup 99m}Tc and {sup 201}Tl is used extensively to measure quantitative cardiac functional parameters. However, factors affecting normal values for myocardial functional parameters and population-specific standards have not yet been established. The aim of the study was to determine the effect of sex, radiotracer, rotation angles and frame rates on resting myocardial wall thickening (WT) and to develop a Japanese standard of normal values for WT. Data from a total of 202 patients with low possibility of having cardiac problems were collected from nine hospitals throughout Japan. Patients were divided into five groups according to study protocol, and WT was evaluated according to the 17-segment and four-region (basal, mid and apical regions and the apex) polar map distribution. WT was generally higher in women than in men irrespective of the use of radiotracers, rotation angles or frame rates, and the difference was highly significant in the mid and apical regions. In any protocol used, resting myocardial thickening in the apex was higher than in the mid and apical regions, and thickening was lowest in the basal region, suggesting heterogeneous regional myocardial thickening (%) in normal subjects. Different rotation angles showed no significant change on WT, but different frame rates and tracers showed significant WT change in both sexes. Percent thickening of the myocardium was significantly higher in imaging by {sup 99m}Tc-labelled tracers than in {sup 201}Tl. Sex, radiotracers and frame rates had a significant effect on myocardial thickening, and the importance of population-specific standards should be emphasized. A normal database can serve as a standard for gated SPECT evaluation of myocardial thickening in a Japanese population and might be applicable to Asian populations having a similar physique. (orig.)

  11. EXPERIENCIAS EXTRASENSORIALES Y EXPERIENCIAS ALUCINATORIAS: EXAMINANDO LA HIPÓTESIS DEL CONTINUO DE EXPERIENCIAS ESQUIZOTÍPICAS/ EXTRASENSORIAL AND HALLUCINATORY EXPERIENCES: EXAMINING THE CONTINUOUS THEORY ON SCHIZOTYPAL EXPERIENCES

    Directory of Open Access Journals (Sweden)

    Alejandro Parra*

    2010-05-01

    Full Text Available RESUMENUna experiencia extrasensorial es aquella en la que parece que la mente de una persona ha adquirido la informaciónremota, es decir, aparentemente sin la mediación de los sentidos humanos conocidos o procesos de inferencia lógica. Portanto, lo «extrasensorial» en la experiencia extrasensorial corresponde a juzgar por las apariencias y no necesariamente a larealidad, mientras que lo «extrasensorial» en la percepcion extrasensorial se refiere a la naturaleza de una presunta realidadparanormal. Se ponen a prueba dos hipótesis específicas: Una muestra de estudiantes argentinos que reportan haber tenidoexperiencias extrasensoriales tienen mayor capacidad de experimentar (1 alucinaciones visuales y táctiles, y (2 propensióna la esquizotipia en comparación con quienes no tuvieron experiencias extrasensoriales. Los resultados mostraron mayornivel de esquizotipia cognitivo-perceptual y propensión a la alucinación en individuos con experiencias que quienes no lastuvieron. Los resultados sugieren que hay procesos disociativos subyacentes, como absorción y propensión a la fantasía,que parecen estar asociadas a las experiencias extrasensoriales.ABSTRACTAn extrasensory experience is one in which it appears that the experient’s mind has acquired information directly, thatis, seemingly without either the mediation of the recognized human senses or the processes of logical inference. The«extrasensory» in extrasensory experience therefore pertains to appearances and not necessarily to reality, whereas the«extrasensory» in extrasensory perception refers to the nature of a hypothesized paranormal reality. Two specific hypothesesare tested: A sample of Argentinean participants who have reported Extrasensorial experiences have a higher capacity for (1visual and tactile hallucination, and (2 schizotypy proneness than non--experients. The results showed a higher level ofcognitive-perceptual schizotypy and hallucination proneness in

  12. Left ventricular synchrony assessed by phase analysis of gated myocardial perfusion SPECT imaging in healthy subjects

    International Nuclear Information System (INIS)

    Wang Yuetao; Wang Jianfeng; Yang Minfu; Niu Rong

    2013-01-01

    Objective: To investigate the value of Cedars-Sinai quantitative gated SPECT (QGS) phase analysis for left ventricular synchrony assessment in healthy subjects. Methods: Seventy-four healthy subjects (41 males, 33 females,average age: (60±13) years) underwent both rest and exercise 99 Tc m -MIBI G-MPI. QGS software was used to analyze the reconstructed rest gated SPECT images automatically, and then the parameters of left ventricular synchrony including phase bandwidth (BW) and phase standard deviation (SD) were obtained. The influences of gender and age (age<60 years, n=36; age ≥ 60 years, n=38) on left ventricular systolic synchronicity were analyzed. The phase angle for original segmental contraction was measured to determine the onset of the ventricular contraction using 17-segment model. Forty healthy subjects were selected by simple random sampling method to evaluate the intra-observer and interobserver repeatability of QGS phase analysis software. Two-sample t test and linear correlation analysis were used to analyze the data. Results: The BW and SD of left ventricular in healthy subjects were (37.22 ±11.71)°, (11.84±5.39)° respectively. Comparisons between male and female for BW and SD yielded no statistical significance (BW: (36.00±9.70)°, (38.73±13.84)°; SD: (11.88±5.56)°, (11.79±5.26)°; t=0.96 and-0.07, both P>0.05); whereas the older subjects (age≥60 years) had larger BW than the others (age<60 years ; (39.95± 12.65)°, (34.33± 10.00)°; t=-2.11, P<0.05) and no statistical significance was shown for SD between the two age groups ((11.18±4.31)°, (12.54±6.33)°; t=1.08, P>0.05). Of the 74 subjects, the mechanical activation started from the ventricular base to apex in 54 subjects (73%), and from apex to base in only 20 subjects (27%). High repeatability of phase analysis was observed for both intra-observer and inter-observer (r=0.867-0.906, all P<0.001). Conclusions: Good left ventricular segmental synchrony is shown in healthy

  13. GATE: Improving the computational efficiency

    International Nuclear Information System (INIS)

    Staelens, S.; De Beenhouwer, J.; Kruecker, D.; Maigne, L.; Rannou, F.; Ferrer, L.; D'Asseler, Y.; Buvat, I.; Lemahieu, I.

    2006-01-01

    GATE is a software dedicated to Monte Carlo simulations in Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET). An important disadvantage of those simulations is the fundamental burden of computation time. This manuscript describes three different techniques in order to improve the efficiency of those simulations. Firstly, the implementation of variance reduction techniques (VRTs), more specifically the incorporation of geometrical importance sampling, is discussed. After this, the newly designed cluster version of the GATE software is described. The experiments have shown that GATE simulations scale very well on a cluster of homogeneous computers. Finally, an elaboration on the deployment of GATE on the Enabling Grids for E-Science in Europe (EGEE) grid will conclude the description of efficiency enhancement efforts. The three aforementioned methods improve the efficiency of GATE to a large extent and make realistic patient-specific overnight Monte Carlo simulations achievable

  14. Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations.

    Science.gov (United States)

    Mao, Yanfei; Yu, Zhicong; Zeng, Gengsheng L

    2015-09-01

    This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue in building a stationary system is to provide sufficient projection view-angles. A GATE (GEANT4 application for tomographic emission) Monte Carlo model was developed to simulate a two-detector stationary cardiac SPECT that uses segmented slant-hole collimators. Each detector contains seven segmented slant-hole sections that slant to a common volume at the rotation center. Consequently, 14 view-angles over 180° were acquired without any gantry rotation. The NCAT phantom was used for data generation and a tailored maximum-likelihood expectation-maximization algorithm was used for image reconstruction. Effects of limited number of view-angles and data truncation were carefully evaluated in the paper. Simulation results indicated that the proposed segmented slant-hole stationary cardiac SPECT system is able to acquire sufficient data for cardiac imaging without a loss of image quality, even when the uptakes in the liver and kidneys are high. Seven views are acquired simultaneously at each detector, leading to 5-fold sensitivity gain over the conventional dual-head system at the same total acquisition time, which in turn increases the signal-to-noise ratio by 19%. The segmented slant-hole SPECT system also showed a good performance in lesion detection. In our prototype system, a short hole-length was used to reduce the dead zone between neighboring collimator segments. The measured sensitivity gain is about 17-fold over the conventional dual-head system. The gate Monte Carlo simulations confirm the feasibility of the proposed stationary cardiac SPECT system with segmented slant

  15. Segmented slant hole collimator for stationary cardiac SPECT: Monte Carlo simulations

    Energy Technology Data Exchange (ETDEWEB)

    Mao, Yanfei, E-mail: ymao@ucair.med.utah.edu [Department of Radiology, Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, Utah 84108 and Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112 (United States); Yu, Zhicong [Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905 (United States); Zeng, Gengsheng L. [Department of Radiology, Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, Utah 84108 and Department of Engineering, Weber State University, Ogden, Utah 84408 (United States)

    2015-09-15

    Purpose: This work is a preliminary study of a stationary cardiac SPECT system. The goal of this research is to propose a stationary cardiac SPECT system using segmented slant-hole collimators and to perform computer simulations to test the feasibility. Compared to the rotational SPECT, a stationary system has a benefit of acquiring temporally consistent projections. The most challenging issue in building a stationary system is to provide sufficient projection view-angles. Methods: A GATE (GEANT4 application for tomographic emission) Monte Carlo model was developed to simulate a two-detector stationary cardiac SPECT that uses segmented slant-hole collimators. Each detector contains seven segmented slant-hole sections that slant to a common volume at the rotation center. Consequently, 14 view-angles over 180° were acquired without any gantry rotation. The NCAT phantom was used for data generation and a tailored maximum-likelihood expectation-maximization algorithm was used for image reconstruction. Effects of limited number of view-angles and data truncation were carefully evaluated in the paper. Results: Simulation results indicated that the proposed segmented slant-hole stationary cardiac SPECT system is able to acquire sufficient data for cardiac imaging without a loss of image quality, even when the uptakes in the liver and kidneys are high. Seven views are acquired simultaneously at each detector, leading to 5-fold sensitivity gain over the conventional dual-head system at the same total acquisition time, which in turn increases the signal-to-noise ratio by 19%. The segmented slant-hole SPECT system also showed a good performance in lesion detection. In our prototype system, a short hole-length was used to reduce the dead zone between neighboring collimator segments. The measured sensitivity gain is about 17-fold over the conventional dual-head system. Conclusions: The GATE Monte Carlo simulations confirm the feasibility of the proposed stationary cardiac

  16. Música y experiencia: De las "sociedades primitivas" a las redes sociales

    Directory of Open Access Journals (Sweden)

    Israel V. Mázquez

    2011-05-01

    Full Text Available El artículo traza un itinerario circular que parte de la experiencia musical en su sentido tradicional de interacción y actividad grupal, sigue con algunas de las características de la figura moderna del oyente solitario y su relación con el espacio público y privado, y termina con las nuevas tecnologías de la información y las redes sociales de la web 2.0, las cuales hacen posible nuevas formas de interactividad y nuevas maneras de fortalecer los lazos de afiliación y sociabilidad a través de la música, hecho que aquí interpretamos como un retorno a los orígenes grupales y comunitarios de la experiencia musical.

  17. Modelo de gestión cultural: Una experiencia con el Qhapaq Ñan en Huánuco

    Directory of Open Access Journals (Sweden)

    Denesy Palacios Jiménez

    2014-06-01

    Full Text Available Objetivos: Plantear el aprovechamiento del patrimonio cultural arqueológico del Qhapaq Ñan en Huánuco en condición de parque cultural, mediante un modelo eficiente de gestión cultural basada en la investigación, protección, conservación y uso social, para convertir a este lugar en un destino turístico y así contribuir con un proyecto no solo para salvaguardarlo sino también para incrementar los ingresos económicos y reducir los niveles de pobreza en la zona. Métodos: Se trata de un estudio que describe y recoge experiencias de gestión cultural respecto a cómo se aprovecha en otros sitios el legado o patrimonio cultural arqueológico, tanto en el ámbito mundial como nacional. La investigación fue cuantitativa y cualitativa, con un alcance correlacional. Se usó el diseño descriptivo, comparativo, analítico, histórico, deductivo. Resultados: El estudio plantea la necesidad de optimizar los recursos para el aprovechamiento del Qhapaq Ñan como parque cultural a través de una adecuada gestión cultural, y que dicho parque comprenderá 68,34 km, desde el tambo de Tambococha o Tunsucancha hasta el tambo de Taparako, por ser uno de los tramos mejor conservados e involucra importantes zonas de patrimonio cultural material e inmaterial. Conclusiones: El Camino Inca en Huánuco es uno de los patrimonios más importantes del país, y es posible ser impulsado como un parque cultural mediante un modelo de gestión cultural, si tenemos en cuenta las diversas experiencias de gestión en el país y en mundo, cuyos aportes deben servir de apoyo para un modelo de gestión en este campo.

  18. Gated SPECT evaluation of left ventricular function using a CZT camera and a fast low-dose clinical protocol: comparison to cardiac magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Giorgetti, Assuero; Masci, Pier Giorgio; Marras, Gavino; Gimelli, Alessia; Genovesi, Dario; Lombardi, Massimo [Fondazione CNR/Regione Toscana ' ' G. Monasterio' ' , Pisa (Italy); Rustamova, Yasmine K. [Azerbaijan Medical University, Department of internal medicine Central Customs Hospital, Baku (Azerbaijan); Marzullo, Paolo [Istituto di Fisiologia Clinica del CNR, Pisa (Italy)

    2013-12-15

    CZT technology allows ultrafast low-dose myocardial scintigraphy but its accuracy in assessing left ventricular function is still to be defined. The study group comprised 55 patients (23 women, mean age 63 {+-} 9 years) referred for myocardial perfusion scintigraphy. The patients were studied at rest using a CZT camera (Discovery NM530c; GE Healthcare) and a low-dose {sup 99m}Tc-tetrofosmin clinical protocol (mean dose 264 {+-} 38 MBq). Gated SPECT imaging was performed as a 6-min list-mode acquisition, 15 min after radiotracer injection. Images were reformatted (8-frame to 16-frame) using Lister software on a Xeleris workstation (GE Healthcare) and then reconstructed with a dedicated iterative algorithm. Analysis was performed using Quantitative Gated SPECT (QGS) software. Within 2 weeks patients underwent cardiac magnetic resonance imaging (cMRI, 1.5-T unit CVi; GE Healthcare) using a 30-frame acquisition protocol and dedicated software for analysis (MASS 6.1; Medis). The ventricular volumes obtained with 8-frame QGS showed excellent correlations with the cMRI volumes (end-diastolic volume (EDV), r = 0.90; end-systolic volume (ESV), r = 0.94; p < 0.001). However, QGS significantly underestimated the ventricular volumes (mean differences: EDV, -39.5 {+-} 29 mL; ESV, -15.4 {+-} 22 mL; p < 0.001). Similarly, the ventricular volumes obtained with 16-frame QGS showed an excellent correlations with the cMRI volumes (EDV, r = 0.92; ESV, r = 0.95; p < 0.001) but with significant underestimations (mean differences: EDV, -33.2 {+-} 26 mL; ESV, -17.9 {+-} 20 mL; p < 0.001). Despite significantly lower values (47.9 {+-} 16 % vs. 51.2 {+-} 15 %, p < 0.008), 8-frame QGS mean ejection fraction (EF) was closely correlated with the cMRI values (r = 0.84, p < 0.001). The mean EF with 16-frame QGS showed the best correlation with the cMRI values (r = 0.91, p < 0.001) and was similar to the mean cMRI value (49.6 {+-} 16 %, p not significant). Regional analysis showed a good

  19. A new automated method for analysis of gated-SPECT images based on a three-dimensional heart shaped model

    DEFF Research Database (Denmark)

    Lomsky, Milan; Richter, Jens; Johansson, Lena

    2005-01-01

    A new automated method for quantification of left ventricular function from gated-single photon emission computed tomography (SPECT) images has been developed. The method for quantification of cardiac function (CAFU) is based on a heart shaped model and the active shape algorithm. The model....... The maximal differences between the CAFU estimations and the true left ventricular volumes of the digital phantoms were 11 ml for the end-diastolic volume (EDV), 3 ml for the end-systolic volume (ESV) and 3% for the ejection fraction (EF). The largest differences were seen in the smallest heart....... In the patient group the EDV calculated using QGS and CAFU showed good agreement for large hearts and higher CAFU values compared with QGS for the smaller hearts. In the larger hearts, ESV was much larger for QGS than for CAFU both in the phantom and patient studies. In the smallest hearts there was good...

  20. Programas de Salud y Género. Mujeres con VIH/SIDA

    Directory of Open Access Journals (Sweden)

    Graciela Enria

    2010-01-01

    Full Text Available La proliferación de trabajos biológicos sobre el proceso del VIH/Sida contrasta con el abordaje de la problemática desde la experiencia de los que lo viven. De entre los involucrados, la mujer se vio implicada desde el comienzo como una de las poblaciones de riesgo de contagiar y de enfermarse. La embarazada, objeto privilegiado de la salud pública, contó con programas especiales y normativas estrictas a través de los programas de salud, que dejaron fuera lo que pasaba con ellas en las relaciones con los compañeros y con ellas mismas; sus experiencias, sus perspectivas, sus nociones de futuro; así como su relación con el sistema de salud y con los médicos. En este trabajo se aplicó una metodología cualitativa basada en entrevistas abiertas a mujeres con VIH de la ciudad de Rosario, Argentina. Los hallazgos remiten a una serie de experiencias que relatan sus estrategias y contradicciones, abriendo puentes hacia la comprensión.

  1. Differential effects comparing exercise and pharmacologic stress on left ventricular function using gated Tc-99m sestamibi SPECT

    International Nuclear Information System (INIS)

    Ohtaki, Yuka; Chikamori, Taishiro; Igarashi, Yuko; Hida, Satoshi; Tanaka, Hirokazu; Hatano, Tsuguhisa; Usui, Yasuhiro; Miyagi, Manabu; Yamashina, Akira

    2008-01-01

    Although post-ischemic stunning has emerged as an important marker for severe coronary artery disease (CAD), differences in stress methods may have different effects on left ventricular (LV) volumes and function. To assess differential effects comparing exercise and pharmacologic stress on the LV measurements, 99m Tc-sestamibi gated single-photon emission computed tomography (SPECT) acquired more than 30 min after stress and at rest was evaluated in 38 patients undergoing adenosine triphosphate (ATP) stress (ATP group) and 38 age- and sex-matched patients subjected to exercise stress (Ex group) among 268 patients with normal SPECT findings. Coronary risk factors and LV volumetric measurements at baseline were similar in the two groups. Compared with volumetric measurements at rest, end-diastolic volume (EDV) increased (72±21 ml to 74±21 ml; P=0.01), end-systolic volume increased (25±12 ml to 28±13 ml; P=0.001), and ejection fraction (EF) decreased after stress (66%±8% to 63%±9%; P<0.002) in the ATP group. In the Ex group, by contrast, no such change was observed. In addition, changes in EDV (3±6 vs. -1±5 ml; P=0.01) and the stress-to-rest ratio of EDV (1.04±0.09 vs. 0.99±0.08; P<0.02) after stress were greater in the ATP than in the Ex group. Differential effects of stress methods on LV volumes persist more than 30 min after the stress. These findings should be kept in mind when interpreting post-ischemic stunning. (author)

  2. Visión activa y aprendizaje perceptual: Cómo la experiencia cambia nuestro mundo visual

    Directory of Open Access Journals (Sweden)

    Carlos M. Hamamé

    2011-06-01

    Full Text Available Nuestra experiencia es capaz de modificar el modo en que percibimos. Este tipo de aprendizaje perceptual nos indica la importancia del observador en la construcción de la percepción. En este artículo se examinan evidencias neurofisiológicas recientes que demuestran la presencia, no sólo de procesos perceptuales, sino también atencionales y de actualización de contexto, en el modo en que nuestra percepción visual cambia con la experiencia. Considerar la experiencia sensorial, junto con el estado actual del observador, ayudará a completar los modelos actuales, que son insuficientes para explicar la visión en condiciones naturales.

  3. DISCRIMINACION ETNICA EN RELATOS DE LA EXPERIENCIA ESCOLAR MAPUCHE EN PANGUIPULLI (CHILE)

    OpenAIRE

    Poblete S,María Pía

    2003-01-01

    El propósito de este artículo es indagar en las percepciones y valoraciones de la experiencia escolar en un contexto interétnico. Presentamos información proveniente de 30 relatos sobre la educación y la experiencia escolar de personas mapuches de la precordillera de la Comuna de Panguipulli. Los resultados nos muestran que las experiencias en la escuela estuvieron marcadas por la discriminación étnica en la mayoría de los entrevistados. La discriminación se vivió en la interacción con profes...

  4. Subjetivación del acto de desplazarse y aspectos psicopatológicos relacionados con experiencias violentas

    Directory of Open Access Journals (Sweden)

    Edith T. Aristizábal Díaz-Granados

    2003-01-01

    Full Text Available Se considera que una de las condiciones que más vulnera, fragiliza y rompe el equilibrio psíquico de un sujeto es el sometimiento a experiencias violentas. En particular, aquellas en las cuales tenga pocas opciones de realizar acciones para detener o evitar el accionar de los violentos y librarse de esa posición de pasividad. De allí surgieron las preguntas que orientaron esta investigación respecto a las diferentes posiciones del sujeto para explicar el acto de desplazarse y su anudamiento con las experiencias violentas que obraron en calidad de traumas. Se trató de comprender la posición subjetiva adoptada por 27 hombres y mujeres desplazados, asentados en comunidades del departamento del Atlántico (Colombia. Se utilizó el diseño deComparación Multicaso (Lessard-Hebert & otros, 1999 y la teoría fundamentada anudados a partir de una matriz de análisis denominada ARIADGE. Se logró organizar en categorías y subcategorías emergentes la manera en que estos sujetos informaron sobre su situación y los efectos producidos. El Proceso de Subjetivación y elaboración realizado por ellos –durante las en -trevistas– permitió transformar su condición de víctimas pasivas de losactores armados, lo cual les permitió a algunos sobrepasar la identificación «desplazados por la violencia política».

  5. Unir Gamificación y Experiencia de Usuario para mejorar la experiencia docente

    Directory of Open Access Journals (Sweden)

    Emiliano Labrador

    2016-06-01

    Full Text Available En unos estudios como son las ingenierías TIC se realiza un tipo de asignatura obligatoria y transversal a todos los alumnos. Es una asignatura que trabaja la parte creativa y la parte crítica del alumno, contando que son alumnos con un tipo de perfil de base principalmente tecnológico. Se trata de una asignatura presencial con soporte de una plataforma online que dispone de todos los recursos necesarios para llevarla a cabo. La gamificación forma parte de la asignatura de primer curso de ingeniería, diseño y usabilidad 1. Su aplicación ha sido diseñada y evaluada para iterar constantemente en la metodología y aplicar cambios continuos que mejoren su diseño y, por lo tanto, que mejoren la aplicación con los alumnos. La gamificación se centra principalmente en respetar el contenido de la asignatura: comunicación, diseño gráfico y usabilidad y experiencia de usuario para tenerlo en cuenta en las mecánicas de juego aplicadas. Tras la gamificación del curso 2013-2014, se realizaron encuestas a los alumnos basadas en técnicas de evaluación de experiencia de usuario para poder obtener datos tanto de la aplicación del contenido académico como de los puntos positivos y negativos de las mecánicas aplicadas. Estas encuestas se contrastaron con los resultados académicos de los alumnos tanto de notas parciales como de notas finales. Este artículo muestra los cambios introducidos en el diseño metodológico, su evaluación y sus posteriores resultados. La pregunta que se pretende responder es: ¿las mejoras introducidas han hecho que mejoren los resultados?

  6. La relación pedagógica: en las fuentes de la experiencia educativa con van Manen

    Directory of Open Access Journals (Sweden)

    Raquel Ayala Carabajo

    2018-01-01

    Full Text Available En este artículo describimos algunos de los significados fundamentales de la pedagogía fenomenológica de Max van Manen. La pedagogía vanmaniana es poco conocida en el contexto hispanoamericano, a diferencia de lo que sucede en otros contextos geográficos; mucho menos conocida que la metodología fenomenológico-hermenéutica que ha desarrollado el autor y que es adoptada en la investigación empírica en muchas y variadas ciencias. Su pedagogía, fruto de investigación fenomenológico-hermenéutica, explora y describe las estructuras esenciales de la experiencia educativa desde el punto de vista existencial o vivido. De esta forma, a lo largo de sus numerosos estudios, van Manen ofrece una profunda y singular comprensión de la vida pedagógica, básicamente, descubierta y descrita a través de sus estructuras o temas esenciales. Se expone aquí, no su metodología, sino una muestra y selección la riqueza de significados fenomenológicos vanmanianos: la naturaleza y condiciones de la relación pedagógica. Un tema que contribuye a aprehender y practicar la pedagogía como una experiencia humana profunda, rica e inefable y con exigencias éticas ineludibles.

  7. Gestión y liderazgo empresarial con perspectiva de género. Voces y experiencias

    Directory of Open Access Journals (Sweden)

    Rosario Rodrígez Díaz

    2016-06-01

    Full Text Available En el presente trabajo se presentan los resultados de una investigación cualitativa sobre gestión y estilos de liderazgo de mujeres propietarias de pymes y autónomas. El objetivo principal es descubrir si existen recursos identificativos en la dirección de sus negocios. Con el focus group se registra una discusión guiada sobre sus experiencias y estrategias de negocio. Participan veinte empresarias andaluzas. Los resultados revelan un liderazgo transformacional. Su know-how destaca por su disposición a la innovación, a la atención por los detalles y a la colaboración. Reconocen el importante papel aprendido de la gestión del hogar de las mujeres de su familia que, en parte, han extrapolado a sus negocios. Configuran un modelo directivo acorde a los nuevos horizontes económico-empresariales.

  8. Impact of endothelial dysfunction on left ventricular remodeling after successful primary coronary angioplasty for acute myocardial infarction. Analysis by quantitative ECG-gated SPECT

    International Nuclear Information System (INIS)

    Matsuo, Shinro; Nakae, Ichiro; Matsumoto, Tetsuya; Horie, Minoru

    2006-01-01

    We hypothesized that endothelial cell integrity in the risk area would influence left ventricular remodeling after acute myocardial infarction. Twenty patients (61±8 y.o.) with acute myocardial infarction underwent 99m Tc-tetrofosmin imaging in the sub-acute phase and three months after successful primary angioplasty due to myocardial infarction. All patients were administered angiotensin-converting enzyme inhibitor after revascularization. Cardiac scintigraphies with quantitative gated SPECT were performed at the sub-acute stage and again 3 months after revascularization to evaluate left ventricular (LV) remodeling. The left ventricular ejection fraction (EF) and end-systolic and end-diastolic volume (ESV, EDV) were determined using a quantitative gated SPECT (QGS) program. Three months after myocardial infarction, all patients underwent cardiac catheterization examination with coronary endothelial function testing. Bradykinin (BK) (0.2, 0.6, 2.0 μg/min) was administered via the left coronary artery in a stepwise manner. Coronary blood flow was evaluated by Doppler flow velocity measurement. Patients were divided into two groups by BK-response: a preserved endothelial function group (n=10) and endothelial dysfunction group (n=10). At baseline, both global function and LV systolic and diastolic volumes were similar in both groups. However, LV ejection fraction was significantly improved in the preserved-endothelial function group, compared with that in the endothelial dysfunction group (42±10% to 48±9%, versus 41±4% to 42±13%, p<0.05). LV volumes progressively increased in the endothelial dysfunction group compared to the preserved-endothelial function group (123±45 ml to 128±43 ml, versus 111±47 ml to 109±49 ml, p<0.05). In re-perfused acute myocardial infarction, endothelial function within the risk area plays an important role with left ventricular remodeling after myocardial infarction. (author)

  9. Simulaciones aumentadas: una experiencia contemporánea del territorio

    OpenAIRE

    Santamarina-Macho, Carlos

    2017-01-01

    Recientemente han comenzado a popularizarse los denominados juegos de realidad aumentada geolocalizada, aplicaciones tecnológicas que ofrecen una experiencia lúdica combinando el mundo real y virtual. El artículo analiza el modo en el que estas herramientas modifican nuestra experiencia territorial. Partiendo de su caracterización teórica, se describen primeramente algunos procesos de creación de “lugar” en el marco de estas realidades mixtas, para continuar con el análisis de su aplicación p...

  10. Four-dimensional MAP-RBI-EM image reconstruction method with a 4D motion prior for 4D gated myocardial perfusion SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Taek-Soo; Tsui, Benjamin M.W. [Johns Hopkins Univ., Baltimore, MD (United States). Dept. of Radiology; Gullberg, Grant T. [Lawrence Berkeley National Laboratory, Berkeley, CA (United States)

    2011-07-01

    We evaluated and proposed here a 4D maximum a posteriori rescaled-block iterative (MAP-RBI)-EM image reconstruction method with a motion prior to improve the accuracy of 4D gated myocardial perfusion (GMP) SPECT images. We hypothesized that a 4D motion prior which resembles the global motion of the true 4D motion of the heart will improve the accuracy of the reconstructed images with regional myocardial motion defect. Normal heart model in the 4D XCAT (eXtended CArdiac-Torso) phantom is used as the prior in the 4D MAP-RBI-EM algorithm where a Gaussian-shaped distribution is used as the derivative of potential function (DPF) that determines the smoothing strength and range of the prior in the algorithm. The mean and width of the DPF equal to the expected difference between the reconstructed image and the motion prior, and smoothing range, respectively. To evaluate the algorithm, we used simulated projection data from a typical clinical {sup 99m}Tc Sestamibi GMP SPECT study using the 4D XCAT phantom. The noise-free projection data were generated using an analytical projector that included the effects of attenuation, collimator-detector response and scatter (ADS) and Poisson noise was added to generated noisy projection data. The projection datasets were reconstructed using the modified 4D MAP-RBI-EM with various iterations, prior weights, and sigma values as well as with ADS correction. The results showed that the 4D reconstructed image estimates looked more like the motion prior with sharper edges as the weight of prior increased. It also demonstrated that edge preservation of the myocardium in the GMP SPECT images could be controlled by a proper motion prior. The Gaussian-shaped DPF allowed stronger and weaker smoothing force for smaller and larger difference of neighboring voxel values, respectively, depending on its parameter values. We concluded the 4D MAP-RBI-EM algorithm with the general motion prior can be used to provide 4D GMP SPECT images with improved

  11. Experiencias, Sensaciones y Demandas de (Inseguridad Ciudadana. Configuraciones complejas en la Argentina reciente

    Directory of Open Access Journals (Sweden)

    Daniel Pedro Míguez

    2013-06-01

    Full Text Available En las últimas décadas, el problema de la inseguridad debida al incremento del delito y el posible impacto sobre la estabilidad de las democracias latinoamericanas ha sido objeto de debate recurrente. En este marco, el presente artículo analiza para el caso argentino la relación entre las experiencias y sensaciones de inseguridad, y su vinculación con las demandas de rigor punitivo. El análisis se basa en la combinación de dos aproximaciones metodológicas. Inicialmente, se toman datos estadísticos de encuestas internacionales, como Latinobarómetro. Estos son luego comparados con datos revelados mediante la observación participante en un barrio pobre de una ciudad intermedia de Argentina. La combinación de fuentes alternativas permite ver la complejidad del proceso. Contrario a lo que muchas veces se ha asumido, no existen vínculos lineales que conduzcan de experiencias y sensaciones de seguridad a demandas de rigor punitivo. La manera en que los actores sociales elaboran sus experiencias de inseguridad es fuertemente situacional y, además, poco sistemática. Hemos encontrado que no necesariamente hay procesos consistentes de ‘construcción de sentido’ que articulen las sensaciones y experiencias de inseguridad con demandas políticas.

  12. Uso de drogas en estudiantes de medicina y su relación con experiencias de maltrato durante la infancia y adolescencia en Uruguay

    OpenAIRE

    Pizzanelli,Miguel; Mann,Robert; Hamilton,Hayley; Erickson,Pat; Brands,Bruna; Giesbrecht,Norman; Wright,Maria da Gloria Miotto; Cumsille,Francisco; Sapag,Jaime; Khenti,Akwatu

    2015-01-01

    Se evaluó la prevalencia del uso y abuso de sustancias psicoactivas en los estudiantes y su relación con las experiencias adversas durante la infancia y la adolescencia en una investigación de tipo exploratorio, transversal, observacional, basada en el autoreporte de 280 estudiantes universitarios. El consumo reportado de sustancias psicoactivas fue del 72.1%. Las tres sustancias psicoactivas más frecuentemente utilizadas en el último año fueron el alcohol (24.3%...

  13. Un nuevo contexto para la experiencia de usuario

    OpenAIRE

    Capossio, Ana Paula

    2014-01-01

    ¿Cómo afecta la incorporación de metodologías de diseño centrado en el usuario (DCU) al momento de diseñar una experiencia para una instalación interactiva? Uno de los factores más importantes para una obra de arte interactivo es el usuario, ya que es el que interactúa directamente con la interfaz de la obra. El desafío del artista es conseguir diseñar una interfaz que los usuarios comprendan y entiendan el significado de la obra. Para poder lograr una mejor experiencia de usuario, el arti...

  14. The role of quantitative Tc-99m-MIBI gated SPECT/F-18-FDG PET imaging in the monitoring of intracoronary bone marrow cell transplantation

    International Nuclear Information System (INIS)

    Kaminek, M.; Myslivecek, M.

    2006-01-01

    A lot of unresolved questions still exist concerning the exact mechanism of the beneficial effects of bone marrow cell (BMC) transplantation for myocardial regeneration. The aim of this communication is to report the cases of patients with and without post-transplantation left ventricular function improvement. To this study we included consecutive patients with irreversible damage after a first acute ST-elevation myocardial infarction treated by coronary angioplasty with stent implantation. The irreversible damage was identified by dobutamine echocardiography and confirmed by rest gated Tc-99m-MIBI gated SPECT and in the majority of patients by F-18-FDG PET imaging as well. Using 4D-MSPECT software, we quantified MIBI/FDG uptake and gated SPECT left ventricular ejection fraction, end-diastolic/end-systolic volumes (LVEF, EDV/ESV) before BMC therapy and 3 months later. The results obtained in the initial group of patients in this study (27 patients in the BMC treated group, 16 patients in the control group) have been published previously [Eur J Nucl Med 2005; 32 (Suppl 1 ): S46]. Among the BMC group, we identified 13 responders to therapy with average LVEF improvement from 43.3%± 11% to 51.4%± 10.4% and EDV/ESV improvement from 145 ml/84 ml to 133 ml/67 ml. The remaining 14 patients were non-responders to therapy with no significant change in LVEF (39.1%±8.1% versus 39.8% ± 7.4%), the EDV/ESV increased from 166 ml/105 ml to 188 ml/116 ml. Responders to the cell therapy had prevailing MIBI uptake in the range of 31-50% of maximum in the infarction territory. On the other hand, non-responders to BMC therapy had prevailing MIBI uptake in the range of 0-30% of maximum. Two cases are presented in this report. Further studies with a larger cohort of patients would be helpful to evaluate our findings. We observed strong interindividual differences in the effectiveness of the cell therapy. Prevailing residual MIBI uptake in the range of 31-50% of maximum was in the

  15. EXAMEN DE POST-EFECTO PARA EXPERIENCIAS ANÓMALO/ PARANORMALES CON UN ABORDAJE HUMANISTA

    OpenAIRE

    PARRA, ALEJANDRO; CORBETTA, JUAN MANUEL

    2014-01-01

    Se presentan los resultados de una investigación que tuvo como objetivos: explorar la utilidad de la terapia grupal para hacer frente a los efectos de las experiencias paranormales y explorar cómo la terapia humanista produce cambios positivos hacia las experiencias anómalo/paranormales. Se les pidió a la muestra (N= 20, rango 22-71 años, M= 45,65, DT= 12,52), 65 % mujeres y 35 % varones, responder un cuestionario autoadministrado de siete preguntas antes y al finalizar su participación en un...

  16. Evolution of the GATE project: new results and developments

    Energy Technology Data Exchange (ETDEWEB)

    Santin, G. [ESA-ESTEC, Keplerlaan 1, 2200 AG Noordwijk (Netherlands); Staelens, S. [ELIS Department, Ghent University, B-9000 Ghent (Belgium); Taschereau, R. [CRUMP Institute for Molecular Imaging, University of California Los Angeles, 700 Westwood Plaza A438, Los Angeles, CA 90095-1770 (United States); Descourt, P. [U650 INSERM, LaTIM, Brest (France); Schmidtlein, C.R. [Memorial Sloan-Kettering Cancer Center, New York, New York, US (United States); Simon, L. [Department of Radiation Oncology, Institut Curie, Paris (France); Visvikis, D. [U650 INSERM, LaTIM, Brest (France); Jan, S. [Service Hospitalier Frederic Joliot (SHFJ), CEA-Orsay, Orsay (France); Buvat, I. [U678 INSERM, CHU Pitie-Salpetriere, Paris (France)

    2007-10-15

    We present the status of the Geant4 Application for Emission Tomography (GATE) project, a Monte Carlo simulator for Single Photon Emission Computed Tomography (SPECT) and Positron annihilation Emission Tomography (PET). Its main features are reminded, including modelling of time dependent phenomena and versatile, user-friendly scripting interface. The focus of this manuscript will be on new developments introduced in the past 4 years. New results have been achieved in the fields of validation on real medical and research PET and SPECT systems, voxel geometries, digitisation, distributed computing and dosimetry.

  17. Evolution of the GATE project: new results and developments

    International Nuclear Information System (INIS)

    Santin, G.; Staelens, S.; Taschereau, R.; Descourt, P.; Schmidtlein, C.R.; Simon, L.; Visvikis, D.; Jan, S.; Buvat, I.

    2007-01-01

    We present the status of the Geant4 Application for Emission Tomography (GATE) project, a Monte Carlo simulator for Single Photon Emission Computed Tomography (SPECT) and Positron annihilation Emission Tomography (PET). Its main features are reminded, including modelling of time dependent phenomena and versatile, user-friendly scripting interface. The focus of this manuscript will be on new developments introduced in the past 4 years. New results have been achieved in the fields of validation on real medical and research PET and SPECT systems, voxel geometries, digitisation, distributed computing and dosimetry

  18. Algunas experiencias de innovación educativa

    Directory of Open Access Journals (Sweden)

    de Haro, J. José

    2009-09-01

    Full Text Available In this article we show some experiences in educational innovation area performed by teachers with students of ESO and Bachelor at Amor de Dios school in Barcelona (www.amordedios. org. We also discuss the characteristics of blogs, wikis and social networks, as well as their potential usage, all based on the experience carried out with the students. We also present some useful guidelines about selection of the various systems depending on teachers’ needs.Se presentan algunas de las experiencias llevadas a cabo en el ámbito de la innovación educativa con alumnos de ESO y Bachillerato en el centro concertado de educación primaria y secundaria Amor de Dios de Barcelona (www.amordedios.org. Se discuten las características de blogs, wikis y redes sociales, así como sus posibilidades de uso, todo ello en base a las experiencias realizadas con los alumnos. Igualmente se presentan algunas directrices que pueden ayudar para la selección de unos sistemas u otros según las necesidades educativas del profesor.

  19. una experiencia de intervención

    Directory of Open Access Journals (Sweden)

    Cecilia Villarreal Montoya

    2007-01-01

    Full Text Available El artículo resume la experiencia de intervención con una familia de la escuela de Villa Esperanza de Pavas. Se trata de un matrimonio con dificultades para disciplinar a sus tres hijos varones de ocho, seis, y cuatro años. En primer lugar, se exponen los principios teóricos y metodológicos, para luego mostrar la aplicación de ellos en el proceso vivido por la familia. Se aplica el modelo de intervención estructural, que busca que la misma familia logre realizar, paso a paso, los cambios requeridos en la dinámica y estructura familiar. En la situación específica de esta familia, se observa el fortalecimiento de la pareja como tal y como madre y padre en la medida que van logrando asumir la autoridad en forma compartida para disciplinar a los hijos. Al compartir esta experiencia, la autora pretende estimular a profesionales en Orientación a asumir el reto de considerar a las familias de la comunidad estudiantil, de las instituciones educativas donde laboran, como parte importante en el quehacer orientador.

  20. Assessment of left ventricular function by gated cardiac blood-pool emission computed tomography using a rotating gamma camera

    International Nuclear Information System (INIS)

    Narita, Michihiro; Kurihara, Tadashi; Murano, Kenichi; Usami, Masahisa; Honda, Minoru

    1991-01-01

    To elucidate the usefulness of gated cardiac blood-pool single photon emission CT (SPECT) with Tc-99m for the evaluation of left ventricular (LV) global and regional functions, 18 patients with coronary artery disease were studied. Thirty-two gated projection images were obtained over 360-degree at 16 frames per cardiac cycle. As LV volume was calculated by integrating the numbers of voxels which constituted LV and multiplying by the volume of a single voxel (0.1143 ml), we performed phantom studies to determine the appropriate cut-off level to detect LV outline. These cut-off levels were affected by the background activity and organ volume itself. So we constructed Volume-Cut-Level-Curve at each background activity. In clinical studies, short axis images which constituted LV were selected and provisional LV volumes were calculated at the cut-off levels of 45, 50 and 55%. These volumes were plotted on the Volume-Cut-Level-Curve and the true cut-off levels were obtained to calculate LV end-diastolic or end-systolic volume (EDV, ESV). The cut-off levels were different at every patient and ED or ES. EDV, ESV and LV ejection fraction obtained by SPECT were correlatd well with those obtained by contrast ventriculography (LVG) (r=0.89, 0.94, 0.94 each, p<0.01). For the LV wall motion analysis, LVGs obtained at two projections were compared with SPECT or gated cardiac blood-pool planar imaging (Planar) in 5 segments. In addition to visual comparison, wall motion scores (WMS) based on the degree of wall motion abnormality were calculated in each segment. Correlation of WMS between LVG and SPECT (r=0.84) was significantly (p<0.01) superior to that between LVG and Planar (r=0.62). Especially in SPECT, wall motion analyses at septal and infero-posterior segments were superior to those in Planar. Although gated SPECT requires relatively long time to perform, it is a useful method to detect LV global and regional functions. (author)

  1. Colaborar con África: la experiencia del retorno Work with Africa: The experience of returning

    Directory of Open Access Journals (Sweden)

    Carmen Jerez Molina

    2010-09-01

    Full Text Available El Hospital de San Juan de Dios colabora desde 2002 con el St. John of God Hospital en Mabesseneh (Sierra Leona cuando éste retoma la actividad asistencial tras la guerra civil del 1991. Parte de la colaboración consiste en enviar cada dos meses un pediatra y una enfermera. Todos estos profesionales inician el proyecto con un concepto de salud occidental, con ideas de cambio... Al volver ¿Qué ha sucedido? ¿Han cambiado el mundo africano o éste les ha cambiado? De estos interrogantes parte nuestra investigación. Metodología: Se realizaron entrevistas no directivas a siete enfermeras colaboradoras con el programa. El enfoque utilizado en esta investigación es el fenomenológico. Los datos se analizaron mediante el enfoque de Taylor y Bogdan para el análisis de datos cualitativos. Resultados: las personas entrevistadas dicen que aprendes a valorar lo que existe en el mundo occidental. La práctica enfermera al principio parece que cambia, pero el ser humano se adapta al entorno tanto cuando uno llega a África como cuando retorna. La impregnación de estas experiencias construye la persona. Encontramos escasas diferencias en personas que han ido más de una vez. Conclusiones: Las experiencias de cada persona pueden ser muy distintas teniendo en cuenta los objetivos de los que se parte. Al igual que la impregnación de lo vivido. Pero sí se hace evidente que, tras el tiempo pasado, el cambio en la práctica asistencial no es significativo.The Hospital de San Juan de Dios collaborates since 2002 with the Hospital from St. John of God Hospital in Mabesseneh (Sierra Leone when the last resumed its activity after the Civil war of 1991. A part of this collaboration consists in sending a nurse and a paediatrician every two months. All these professional start the project with a "Western" concept of Health, with some ideas of change.... When they are back at home... What has happened? Have they changed the African world or has it changed then

  2. Quantitative gated SPECT- a comparative study of two algorithms for parameters of perfusion and LV function

    International Nuclear Information System (INIS)

    Ali, A.Z.

    2007-01-01

    Full text: Aim: To compare the perfusion and LV function parameters as quantified by 4D-MSPECT and ECT in the same patient group and a qualitative comparison of the reconstructed slices by two different experts. Materials and methods: Thirty-one consecutive patients underwent gated myocardial perfusion SPECT using a two-day protocol. The gated and ungated data were reconstructed by back projection method. Quantitative analysis was performed on the same set of reconstructed slices by 4D-MSPECT and Emory Cardiac Tool Box. The reconstructed slices were read qualitatively by two different experts on their respective systems. Polar map and functional analysis was performed in both softwares and the results were compared. Results: The concordance between the two experts qualitatively was seen in 78/93(84%) coronary territories. The polar map defects were comparable in LAD (r-value of 0.87) and LCX (r-value of 0.76) territories whereas RCA defects (r-value of 0.04) were not at all correlating. The defect severity showed concordance in 68/93 (73%) coronary territories. There was concordance between 4DMSPECT and the qualitative interpretation in 84/93 (90%) coronary territories whereas ECT showed concordance in only 70/93(75%) coronary territories. The overall sensitivity is marginally higher for ECT (100% vs. 96%) but the overall specificity is much higher with 4 DMSPECT (88% vs. 65%). ESV showed good correlation(r=0.94) of the two softwares with no significant difference in means. EDV and LVEF although had good correlation(r = 0.96 and 0.89) showed high difference in means (p<0.01). Conclusion: Between 4D-MSPECT and ECT, 4D-MSPECT is marginally superior to ECT with reference to qualitative interpretation in view of better specificity. The LVEF values between the two softwares should also not be used interchangeably. (author)

  3. Performance of Myocardial Perfusion Imaging Using Multi-focus Fan Beam Collimator with Resolution Recovery Reconstruction in a Comparison with Conventional SPECT

    International Nuclear Information System (INIS)

    Matsutomo, Norikazu; Nagaki, Akio; Sasaki, Masayuki

    2014-01-01

    IQ-SPECT is an advanced high-speed SPECT modality for myocardial perfusion imaging (MPI), which uses a multi-focus fan beam collimator with resolution recovery reconstruction. The aim of this study was to compare IQ-SPECT with conventional SPECT in terms of performance, based on standard clinical protocols. In addition, we examined the concordance between conventional and IQ-SPECT in patients with coronary artery disease (CAD). Fifty-three patients, undergoing rest-gated MPI for the evaluation of known or suspected CAD, were enrolled in this study. In each patient, conventional SPECT ( 99m Tc-tetrofosmin, 9.6 min and 201 Tl, 12.9 min) was performed, immediately followed by IQ-SPECT, using a short acquisition time (4.3 min for 99m Tc-tetrofosmin and 6.2 min for 201 Tl). A quantitative analysis was performed on an MPI polar map, using a 20-segment model of the left ventricle. An automated analysis by gated SPECT was carried out to determine the left ventricular volume and function including end-diastolic volume (EDV), end-systolic volume (ESV), and left ventricular ejection fraction (LVEF). The degree of concordance between conventional SPECT and IQ-SPECT images was evaluated according to linear regression and Bland-Altman analyses. The segmental percent uptake exhibited a significant correlation between IQ-SPECT and conventional SPECT (P<0.05). The mean differences in 99m Tc-tetrofosmin studies were 1.1±6.6% (apex), 2.8±5.7% (anterior wall), 2.9±6.2% (septal wall), 4.9±6.7% (lateral wall), and 1.8±5.6% (inferior wall). Meanwhile, regarding the 201 Tl-SPECT studies, these values were 1.6±6.9%, 2.0±6.6%, 2.1±5.9%, 3.3±7.2%, and 2.4±5.8%, respectively. Although the mean LVEF in IQ-SPECT tended to be higher than that observed in conventional SPECT (conventional SPECT=64.8±11.8% and IQ-SPECT=68.3±12.1% for 99m Tc-tetrofosmin; conventional SPECT= 56.0±11.7% and IQ-SPECT=61.5±12.2% for 201 Tl), quantitative parameters were not significantly different between

  4. Prepulse inhibition is associated with attention, processing speed, and 123I-FP-CIT SPECT in Parkinson's disease

    DEFF Research Database (Denmark)

    Zoetmulder, Marielle; Biernat, Heidi B; Nikolic, Miki

    2014-01-01

    BACKGROUND: Prepulse inhibition is a measure of sensorimotor gating, which reflects the ability to filter or 'gate' irrelevant information. Prepulse inhibition is dramatically altered in basal ganglia disorders associated with dysfunction in the midbrain dopaminergic system, and corresponding......'s disease have been extensively studied in relation to motor function, less is known about the potential role of sensorimotor processes in cognitive function. OBJECTIVE: We investigated the relationship between prepulse inhibition, cognition and nigrostriatal dysfunction, as measured with 123I......-FP-CIT-SPECT scanning, in patients with Parkinson's disease. METHODS: 38 Parkinson patients were assessed with prepulse inhibition, neuropsychological tests, and neurological investigation. A subset of these patients underwent 123I-FP-CIT-SPECT scanning. RESULTS: Patients with a higher level of prepulse inhibition...

  5. El principio de confiabilidad en el registro electoral. La experiencia cubana

    Directory of Open Access Journals (Sweden)

    Raudiel Peña Barrios

    2015-01-01

    Full Text Available Este artículo pretende dar una panorámica acerca del contenido del principio de confiabilidad en materia registral, específicamente, en sede del registro de electores. Abordaremos las implicaciones que dicho principio tiene para la información que es manejada por los registros electorales, así como las medidas que pueden desarrollarse con el objetivo de lograr niveles cada vez más altos de confiabilidad. En este sentido, expondremos experiencias que se basan fundamentalmente en la utilización de la biometría y en el fortalecimiento del registro civil, como sustento, este último, de un registro electoral eficiente teniendo en cuenta la relación natural que existe entre ambos. Además, ofreceremos un análisis detallado de los puntos de ruptura del registro de electores cubano con el citado principio, con el objetivo de analizar la experiencia de Cuba. Por último, expondremos algunas ideas generales que pudieran contribuir al perfeccionamiento del registro electoral cubano

  6. Formas de mirar y de hacer ver: la experiencia visual en el trabajo de campo del topógrafo

    Directory of Open Access Journals (Sweden)

    Carla Lois

    2013-06-01

    Full Text Available Hacia mediados del siglo XX estaba instalada la idea de que el objetivo de los topógrafos era capturar la morfología del terreno para transcribirla a un lenguaje gráfico estable y “universal”. Este modo de concebir la cartografía se entroncaba con una convicción más generalizada: que todo mapa era el producto de una abstracción intelectual que resultaba de procesos de mensura realizados con “objetividad”. Sin embargo, el trabajo del topógrafo en el terreno consistía en la puesta en acción de formas de percibir y registrar el espacio basadas en experiencias sensibles de observación visual. Esas experiencias eran volcadas en registros visuales que luego serían los insumos utilizados para elaborar el mapa. En este trabajo proponemos conectar la experiencia sensible del terreno y la inscripción cartográfica con la experiencia que un ojo entrenado tiene al observar el mapa.

  7. Determination of Three-Dimensional Left Ventricle Motion to Analyze Ventricular Dyssyncrony in SPECT Images

    DEFF Research Database (Denmark)

    de Sá Rebelo, Marina; Aarre, Ann Kirstine Hummelgaard; Clemmesen, Karen-Louise

    2010-01-01

    A method to compute three-dimension (3D) left ventricle (LV) motion and its color coded visualization scheme for the qualitative analysis in SPECT images is proposed. It is used to investigate some aspects of Cardiac Resynchronization Therapy (CRT). The method was applied to 3D gated-SPECT images...... sets from normal subjects and patients with severe Idiopathic Heart Failure, before and after CRT. Color coded visualization maps representing the LV regional motion showed significant difference between patients and normal subjects. Moreover, they indicated a difference between the two groups...

  8. Una visión panorámica de las experiencias de Telesalud en Perú

    Directory of Open Access Journals (Sweden)

    Ernesto Gozzer Infante

    Full Text Available El artículo presenta las principales experiencias de telesalud realizadas en el Perú entre los años 2002 al 2010. Analiza información de literatura publicada y documentos no publicados acerca de experiencias de telesalud públicas y privadas. A partir de esta información se consultó con 26 expertos acerca de las características de las experiencias de telesalud identificadas. Se generó una base de datos de 38 experiencias, que se describen y analizan en esta publicación. Se presenta reflexiones y recomendaciones para ampliar el uso de la telesalud en el Perú

  9. Estilos de defensa predominantes en relación con experiencias anómalo/paranormales (Predominant Defenses Styles in Relation to Abnormal / Paranormal Experiences

    Directory of Open Access Journals (Sweden)

    Alejandro Parra

    2015-06-01

    Full Text Available RESUMEN: El concepto de mecanismos de defensa tiene sus orígenes en la teoría psicoanalítica, que se centra más en el proceso de las defensas que en el objetivo de las defensas. El presente estudio examinó las diferencias entre individuos que tienen experiencias anómalo/paranormales y tres estilos defensivos (factor maduro, neurótico e inmaduro y quienes no han tenido tales experiencias. Estudiantes universitarios (60 % mujeres y 40 % varones, Edad promedio = 33.87 años recibieron el Cuestionario de Estilos de Defensa (DSQ-40 y diez preguntas que exploran varias experiencias anómalo/paranormales. Las personas reportaron una alta frecuencia de experiencias, tales como déjà-vu, sueños de percepción extrasensorial (PES, telepatía y recuerdos de vidas pasadas. Los resultados también mostraron mayor nivel de experiencias paranormales y defensas maduras, así como defensas neuróticas, en comparación con individuos sin experiencias. Aunque la naturaleza del estudio es francamente exploratoria, el autor sugiere que algunas de estas experiencias atribuidas a causas paranormales parecen servir como un mecanismo de protección a potenciales eventos traumáticos, mejorar el bienestar subjetivo del individuo o – al menos– evitar o disminuir las consecuencias perturbadoras de los eventos negativos de la vida. Por lo tanto, las experiencias paranormales podrían corresponder a rasgos no patológicos que producen cambios en la «homeostasis» psicológica. ABSTRACT: The concept of defense mechanisms has its origins in psychoanalytic theory, which focuses more on the defenses´process than on the objective of defenses. The present study examined the differences between individuals who have abnormal/paranormal experiences – and three defensive styles (mature, neurotic, and immature factor, and those who have not had such experiences. College students (60 % women and 40 % men, mean age = 33.87 years old received the Defense Styles

  10. Intervención pedagógica con niños y niñas menores de tres años: Experiencia en la casa infantil universitaria

    Directory of Open Access Journals (Sweden)

    Jeanneth Cerdas Núñez

    2006-01-01

    Full Text Available En este artículo se reflexiona acerca de la importancia de los primeros años de vida en el desarrollo integral del ser humano determinando la importancia de una intervención pedagógica adecuada, para lo cual se comparte la experiencia de la práctica docente con infantes menores de tres años que realizan las estudiantes de la carrera de Bachillerato y Licenciatura en Educación Preescolar de la Universidad de Costa Rica. Se refiere a la experiencia desarrollada durante el año 2005 en la Casa Infantil Universitaria, la cual constituyó según la apreciación de las estudiantes, las familias y el personal del centro, una valiosa oportunidad para favorecer el desarrollo integral de niños y niñas menores de tres años.

  11. Brain SPECT. SPECT in der Gehirndiagnostik

    Energy Technology Data Exchange (ETDEWEB)

    Feistel, H. (Erlangen-Nuernberg Univ., Erlangen (Germany). Nuklearmedizinische Klinik mit Poliklinik)

    1991-12-01

    Brain SPECT investigations have gained broad acceptance since the introduction of the lipophilic tracer Tc-99m-HMPAO. Depending on equipment and objectives in different departments, the examinations can be divided into three groups: 1. Under normal conditions and standardised patient preparation the 'rest' SPECT can be performed in every department with a tomographic camera. In cerebrovascular disease there is a demand for determination of either the perfusion reserve in reversible ischemia or prognostic values in completed stroke. In cases of dementia, SPECT may yield useful results according to differential diagnosis. Central cerebral system involvement in immunologic disease may be estimated with higher sensitivity than in conventional brain imaging procedures. In psychiatric diseases there is only a relative indication for brain SPECT, since results during recent years have been contradictory and may be derived only in interventional manner. In brain tumor diagnostics SPECT with Tl-201 possibly permits grading. In inflammatory disease, especially in viral encephalitis, SPECT may be used to obtain early diagnosis. Normal pressure hydrocephalus can be distinguished from other forms of dementia and, consequently, the necessity for shunting surgery can be recognised. 2. In departments equipped for emergency cases an 'acute' SPECT can be performed in illnesses with rapid changing symptoms such as different forms of migraine, transient global amnesia, epileptic seizures (so-called 'ictal SPECT') or urgent forms like trauma. 3. In cooperation with several departments brain SPECT can be practised as an interventional procedure in clinical and in scientific studies. (orig./MG).

  12. EXPERIENCIA DE TRABAJO INTERDISCIPLINARIO EN ALFABETIZACIÓN BÁSICA CON MUJERES, PROMOCIÓN DE SU SALUD Y DERECHOS

    Directory of Open Access Journals (Sweden)

    Marcela Sanabria Hernández

    2015-01-01

    Full Text Available El artículo presenta una experiencia de trabajo interinstitucional e interdisciplinaria, entre la Caja Costarricense de Seguro Social- Área de Salud Goicoechea 2, Servicio de Trabajo Social con la Universidad Estatal a Distancia, Cátedra de Psicopedagogía, realizada en el Área de Salud Goicoechea 2, referente a la alfabetización básica con mujeres adultas, vecinas de los cantones de Moravia y Goicoechea, San José, Costa Rica. El proceso se llevó a cabo a partir de una metodología grupal socioeducativa para facilitar en las usuarias conocimientos básicos de alfabetización, útiles en sus actividades cotidianas, las cuales facilitarán su empoderamiento y atención integral de la salud. Se logró la implementación exitosa del proyecto, según los objetivos de aprendizaje propuestos, y se denotaron situaciones de desigualdad social que prevalecen en Costa Rica por categorías tales como el género y las condiciones socioeconómicas.Asimismo, se obtuvo la posibilidad de que a nivel interintitucional se vinculen proyectos para atender las necesidades de la población.

  13. Una experiencia de aprendizaje intergeneracional con alumnos universitarios a través de la novela gráfica = An experience of intergenerational learning with college students through the graphic novel

    Directory of Open Access Journals (Sweden)

    Elisa Larrañaga Rubio

    2017-09-01

    Full Text Available Resumen: Presentamos una experiencia docente realizada conjuntamente con alumnos del Grado de Humanidades y alumnos de la Universidad de Mayores. Nuestra herramienta de trabajo ha sido la novela gráfica Arrugas. La incorporación de la novela gráfica en la docencia universitaria nos está posibilitando el cambio deseado en la mayor autonomía del proceso enseñanza-aprendizaje en nuestro alumnado, permitiendo el traspaso de la tradicional docencia universitaria basada en el rol expositivo del docente, hacia un proyecto común con mayor peso de los discentes. La experiencia desarrollada ha favorecido la interrelación entre los alumnos de la Universidad de Mayores y los alumnos de grado. Relación que se ha mantenido más allá de la experiencia de aula. Es importante destacar la alta satisfacción de todos los estudiantes. Todos mostraron su deseo de continuar la docencia conjunta en otras experiencias.Abstract: We present a teaching experience carried out with the degree of Humanities students and students of the University Programs for Seniors. Our tool has been the graphic novel wrinkles. The incorporation of the graphic novel in university teaching us is enabling the change desired greater autonomy process teaching and learning in our students, allowing the transfer of traditional university teaching based on the expository role of the teacher, towards a common project with greater weight of the learners. The experience developed to favor the interrelation between the senior citizens University students and grade students. The relationship has lasted beyond the classroom experience. It is important to highlight the high satisfaction of all students. All showed their desire to continue the joint teaching in other experiences.

  14. Experiencia de la terapia con lokomat en pacientes portadores de parálisis cerebral y síndromes atáxicos, instituto de rehabilitación infantil teletón concepción Chile

    Directory of Open Access Journals (Sweden)

    D. Lorena Llorente, DRA.

    2014-03-01

    En el Instituto de Rehabilitación Infantil Teletón Concepción el Lokomat existe desde 2008. Esto ha permitido recoger experiencias relacionadas con los cambios observados en el desempeño de la marcha de niños con distintos trastornos de la marcha de origen neurológico tratados con esta órtesis robótica. Se presentan resultados preliminares de tres líneas de investigación que se están desarrollando actualmente incluyendo niños con Parálisis Cerebral Hemipléjica, Parálisis Cerebral dipléjica y con Síndromes Atáxicos.

  15. Formulación participativa del presupuesto en el municipio Caroní: comparación con la experiencia de Porto Alegre

    Directory of Open Access Journals (Sweden)

    María Pilar GARCÍA-GUADILLA

    2009-11-01

    Full Text Available RESUMEN: El presente artículo evalúa la experiencia de descentralización local que se lleva a cabo desde 1990 hasta la fecha en el Municipio Caroní de Ciudad Guayana, Venezuela. Focalizándose en la elaboración del presupuesto participativo, se identifican los alcances y limitaciones de algunas prácticas de democracia participativa tales como la participación ciudadana en la gestión local. Finalmente, se hace una comparación con la experiencia de elaboración del presupuesto en forma participativa del municipio de Porto Alegre (Brasil estableciéndose las semejanzas y diferencias entre ambos procesos en lo que se refiere a los siguientes aspectos: la apertura de nuevos espacios de participación, el acceso a la información, la satisfacción de las demandas sociales en consonancia con los criterios de equidad y eficiencia, la existencia y utilización de mecanismos de control de la gestión y la posibilidad de trascender desde la participación local hacia la cultura política de ciudadanos o ciudadanía activa.ABSTRACT: This article evaluates the experience with local decentralization of the Municipio Caroní, in Venezuela since 1990 from the point of view of participatory democracy. It analyzes the decision making process around the elaboration of the socalled "Participatory Budgeting" and compares it with the case of the Municipio Porto Alegre in Brazil in order to draw some conclussión about: the opening of new spaces for participation, access to vital information, residente" satisfacction of their demands according to the criteria of efficiency and equity, mechanisms of control over the representatives and the possibility to trascend from a culture of local participatión to a citizens and active culture.

  16. A newly developed maneuver, field change conversion (FCC), improved evaluation of the left ventricular volume more accurately on quantitative gated SPECT (QGS) analysis

    International Nuclear Information System (INIS)

    Tajima, Osamu; Shibasaki, Masaki; Hoshi, Toshiko; Imai, Kamon

    2002-01-01

    The purpose of this study was to investigate whether a newly developed maneuver that reduces the reconstruction area by a half more accurately evaluates left ventricular (LV) volume on quantitative gated SPECT (QGS) analysis. The subjects were 38 patients who underwent left ventricular angiography (LVG) followed by G-SPECT within 2 weeks. Acquisition was performed with a general purpose collimator and a 64 x 64 matrix. On QGS analysis, the field magnification was 34 cm in original image (Original: ORI), and furthermore it was changed from 34 cm to 17 cm to enlarge the re-constructed image (Field Change Conversion: FCC). End-diastolic volume (EDV) and end-systolic volume (ESV) of the left ventricle were also obtained using LVG. EDV was 71±19 ml, 83±20 ml and 98±23 ml for ORI, FCC and LVG, respectively (p<0.001: ORI versus LVG, p<0.001: ORI versus FCC, p<0.001: FCC versus LVG). ESV was 28±12 ml, 34±13 ml and 41±14 ml for ORI, FCC and LVG, respectively (p<0.001: ORI versus LVG, p<0.001: ORI versus FCC, p<0.001: FCC versus LVG). FCC was better than ORI for calculating LV volume in clinical cases. Furthermore, FCC is a useful method for accurately measuring the LV volume on QGS analysis. (author)

  17. Experiencias, sensaciones y demandas de (inseguridad ciudadana: configuraciones complejas en la Argentina reciente

    Directory of Open Access Journals (Sweden)

    Daniel P. Míguez

    2013-06-01

    Full Text Available En las últimas décadas, el problema de la inseguridad debida al incremento del delito y elposible impacto sobre la estabilidad de las democracias latinoamericanas ha sido objeto dedebate recurrente. En este marco, el presente artículo analiza para el caso argentino la relaciónentre las experiencias y sensaciones de inseguridad, y su vinculación con las demandas derigor punitivo. El análisis se basa en la combinación de dos aproximaciones metodológicas.Inicialmente, se toman datos estadísticos de encuestas internacionales, como Latinobarómetro.Estos son luego comparados con datos revelados mediante la observación participante en unbarrio pobre de una ciudad intermedia de Argentina. La combinación de fuentes alternativaspermite ver la complejidad del proceso. Contrario a lo que muchas veces se ha asumido,no existen vínculos lineales que conduzcan de experiencias y sensaciones de seguridad ademandas de rigor punitivo. La manera en que los actores sociales elaboran sus experienciasde inseguridad es fuertemente situacional y, además, poco sistemática. Hemos encontradoque no necesariamente hay procesos consistentes de ‘construcción de sentido’ que articulenlas sensaciones y experiencias de inseguridad con demandas políticas.

  18. Examen de post-efecto para experiencias anómalo/ paranormales con un abordaje humanista

    OpenAIRE

    Alejandro Parra; Juan Manuel Corbetta

    2014-01-01

    Se presentan los resultados de una investigación que tuvo como objetivos: explorar la utilidad de la terapia grupal para hacer frente a los efectos de las experiencias paranormales y explorar cómo la terapia humanista produce cambios positivos hacia las experiencias anómalo/paranormales. Se les pidió a la muestra (N= 20, rango 22-71 años, M= 45,65, DT= 12,52), 65 % mujeres y 35 % varones, responder un cuestionario autoadministrado de siete preguntas antes y al finalizar su participación en un...

  19. Gestión del marketing sensorial sobre la experiencia del consumidor

    Directory of Open Access Journals (Sweden)

    Leonardo Ortegón-Cortázar

    2016-01-01

    Full Text Available El rápido desarrollo de mercados con productos competitivos de difícil diferenciación y consumidores mejor informados que demandan experiencias memorables, justifican estudiar los elementos sensoriales que pueden potenciar e influir positivamente sobre dichas experiencias. El objetivo de este artículo es analizar el estado del arte respecto a la gestión y uso del marketing sensorial sobre la experiencia del consumidor. El diseño de investigación es no experimental documental, con un tipo de estudio descriptivo, empleando fuentes de recolección de información secundarias, mediante un arqueo bibliográfico de revistas de impacto que figuran en bases de datos de libre acceso. Los resultados revelan la dominancia del sentido de la visión sobre la persuasión y las actividades de marketing, mientras que el sentido del olfato demuestra mayor influencia sobre el nivel de recuerdo y evocación de información. Se concluye la utilidad de jerarquizar por nivel de influencia las actividades de estimulación sensorial en marketing a partir del funcionamiento y participación de los sentidos humanos y poder combinar dichas estimulaciones como medio para maximizar la experiencia del consumidor y distinguir la oferta de valor, considerando el grado de diferenciación, la favorabilidad y la fuerza de la actividad sensorial basada en planeación estratégica empresarial.

  20. Experiencias y vivencias del embarazo en adolescentes explicadas desde lo social

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    VIRGINIA INÉS SOTO

    2008-12-01

    Full Text Available Describir y explicar desde lo social las experiencias y vivencias de las adolescentes embarazadas, como el contexto para una provisión de cuidado integral, individualizado y contextualizado, es necesario para la práctica de enfermería, y tratar este fenómeno como hecho social exige asimilar las realidades del mundo social a las del mundo exterior, adoptando el principio de que se ignora por completo lo que son, reconociendo que el hecho social no puede ser modificado por un simple decreto de la voluntad, sino que exige un esfuerzo laborioso, considerando la experiencia desde los ámbitos interno y externo. Presentar un marco conceptual y referencial desde lo social, interpretando la experiencia y la vivencia, permitirá a la enfermera comprender este fenómeno cuando dichas experiencias involucran o ponen en riesgo la salud de la adolescente gestante, máxime que la práctica clínica de enfermería se ha estudiado primariamente desde una perspectiva sociológica, pues comparte una importancia social destacada y un fin social, centrada en facilitar, apoyar y atender a los individuos, familias, comunidades y/o sociedades para realzar, mantener y recuperar la salud, y reducir y aliviar los efectos de la enfermedad, con el resultado explícito de promover la calidad de vida relacionada con la salud dentro de contextos ambientales inmediatos y más amplios.

  1. Experiencias sociales y educativas en los procesos de participación con niñas y niños jóvenes en la ciudad de Sevilla entre los años 2005/2008.

    OpenAIRE

    Ruiz Morales, Jorge

    2014-01-01

    Este trabajo de investigación social y educativa surge de las experiencias profesionales y personales vividas por el investigador en relación con los procesos de dinamización y participación con niños/as, chavales/as y jóvenes de la Ciudad de Sevilla, en el contexto de los Presupuestos Participativos, en el CEIP Adriano como estudio de caso, y en los procesos que se vivieron en Pino Montano. Este trabajo goza de actualidad con la puesta en marcha en Sevilla del proyecto “Sevilla Ciudad Amiga ...

  2. The origins of SPECT and SPECT/CT

    Energy Technology Data Exchange (ETDEWEB)

    Hutton, Brian F. [University College London, Institute of Nuclear Medicine, London (United Kingdom); University of Wollongong, Centre for Medical Radiation Physics, Wollongong, NSW (Australia)

    2014-05-15

    Single photon emission computed tomography (SPECT) has a long history of development since its initial demonstration by Kuhl and Edwards in 1963. Although clinical utility has been dominated by the rotating gamma camera, there have been many technological innovations with the recent popularity of organ-specific dedicated SPECT systems. The combination of SPECT and CT evolved from early transmission techniques used for attenuation correction with the initial commercial systems predating the release of PET/CT. The development and acceptance of SPECT/CT has been relatively slow with continuing debate as to what cost/performance ratio is justified. Increasingly, fully diagnostic CT is combined with SPECT so as to facilitate optimal clinical utility. (orig.)

  3. Wide beam reconstruction for half-dose or half-time cardiac gated SPECT acquisitions: optimization of resources and reduction in radiation exposure

    International Nuclear Information System (INIS)

    Marcassa, Claudio; Campini, Riccardo; Zoccarato, Orazio; Calza, Paolo

    2011-01-01

    A new iterative reconstruction algorithm (WBR trademark) has been recently proposed for cardiac single photon emission computed tomography (SPECT). The WBR trademark technology is designed to reduce noise, improving lesion identification without affecting the image resolution, allowing SPECT studies with reduced count statistic. This allows for either half-time (HT) or half-dose (HD) cardiac SPECT, with image quality and quantitative data comparable to standard-time (ST) or standard-dose (SD) SPECT. Few data exist on the comparison between conventional filtered backprojection (FBP) and this new algorithm in a clinical setting. The aim of this study was to compare the performance of FBP and WBR trademark. Phantoms studies were performed to compare spatial resolution and contrast recovery with FBP, ordered subset expectation maximization (OSEM) and WBR trademark. A group of 92 patients, with different cardiac pathology, scheduled for a stress-rest SPECT were studied: 52 patients (group A) were injected with a SD of tracer and underwent both ST and HT SPECT; 40 patients (group B) were injected with a half dose of tracer and underwent ST SPECT and immediately after an additional SPECT at double time/projection (DT), to compensate for the low count statistic. A 2-day 99m Tc-sestamibi protocol was used in all patients. SD/ST and HD/DT SPECT were reconstructed with a conventional FBP; SD/HT and HD/ST SPECT were reconstructed with WBR trademark. The summed stress score (SSS) and summed rest score (SRS) were calculated; the left ventricular ejection fraction (LVEF) was automatically derived. In group A (SD), no significant differences were observed between ST FBP SPECT and HT WBR trademark in SSS (11.1 and 11.7, respectively) and SRS (9.4 and 10.3, respectively, NS). LVEF on rest acquisitions was also comparable (50% on ST SPECT and 49% on HT SPECT, NS); LVEF on post-stress studies in HT SPECT (46%) was lower than ST SPECT (50%), although not statistically significant. In

  4. Wide beam reconstruction for half-dose or half-time cardiac gated SPECT acquisitions: optimization of resources and reduction in radiation exposure

    Energy Technology Data Exchange (ETDEWEB)

    Marcassa, Claudio [S. Maugeri Fnd, IRCCS, Scientific Institute of Veruno, Cardiology Department (Italy); Campini, Riccardo; Zoccarato, Orazio; Calza, Paolo [S. Maugeri Fnd, IRCCS, Scientific Institute of Veruno, Nuclear Medicine Department (Italy)

    2011-03-15

    A new iterative reconstruction algorithm (WBR trademark) has been recently proposed for cardiac single photon emission computed tomography (SPECT). The WBR trademark technology is designed to reduce noise, improving lesion identification without affecting the image resolution, allowing SPECT studies with reduced count statistic. This allows for either half-time (HT) or half-dose (HD) cardiac SPECT, with image quality and quantitative data comparable to standard-time (ST) or standard-dose (SD) SPECT. Few data exist on the comparison between conventional filtered backprojection (FBP) and this new algorithm in a clinical setting. The aim of this study was to compare the performance of FBP and WBR trademark. Phantoms studies were performed to compare spatial resolution and contrast recovery with FBP, ordered subset expectation maximization (OSEM) and WBR trademark. A group of 92 patients, with different cardiac pathology, scheduled for a stress-rest SPECT were studied: 52 patients (group A) were injected with a SD of tracer and underwent both ST and HT SPECT; 40 patients (group B) were injected with a half dose of tracer and underwent ST SPECT and immediately after an additional SPECT at double time/projection (DT), to compensate for the low count statistic. A 2-day {sup 99m}Tc-sestamibi protocol was used in all patients. SD/ST and HD/DT SPECT were reconstructed with a conventional FBP; SD/HT and HD/ST SPECT were reconstructed with WBR trademark. The summed stress score (SSS) and summed rest score (SRS) were calculated; the left ventricular ejection fraction (LVEF) was automatically derived. In group A (SD), no significant differences were observed between ST FBP SPECT and HT WBR trademark in SSS (11.1 and 11.7, respectively) and SRS (9.4 and 10.3, respectively, NS). LVEF on rest acquisitions was also comparable (50% on ST SPECT and 49% on HT SPECT, NS); LVEF on post-stress studies in HT SPECT (46%) was lower than ST SPECT (50%), although not statistically significant

  5. Experiencias formativas de uso didáctico de la realidad aumentada con alumnado del grado de educación primaria en la universidad de Málaga

    Directory of Open Access Journals (Sweden)

    Noelia Margarita Moreno Martínez

    2017-01-01

    Full Text Available El presente estudio describe experiencias innovadoras universitarias orientadas hacia la formación en el uso didáctico de la realidad aumentada de dos grupos de estudiantes del Grado de Educación Primaria de la Universidad de Málaga. Dichas experiencias se han desarrollado con 105 estudiantes a través de seminarios formativos de dos horas en las asignaturas de Didáctica General y Didáctica de las Ciencias Sociales durante el curso académico 2015-2016. Los objetivos de dicho estudio estaban orientados hacia el conocimiento de herramientas de realidad aumentada para dispositivos móviles y ordenadores, el desarrollo de actitudes positivas ante esta tecnología y la adquisición de competencias de uso de estos recursos desde un punto de vista didáctico para su implementación con un carácter prospectivo en las instituciones educativas en las que ejercerán su labor docente. Y tras los resultados obtenidos, se constata que en general los futuros maestros encuestados consideran la tecnología basada en la realidad aumentada como un recurso reforzador, amplificador y enriquecedor para crear nuevos formatos de escenarios de aprendizaje adaptados a las características y demandas del alumnado diverso desde una perspectiva inclusiva.

  6. Empoderamiento en mujeres mexicanas: Experiencias de mujeres líderes de México

    Directory of Open Access Journals (Sweden)

    Julita Elemí Hernández Sánchez

    2015-06-01

    Full Text Available En artículo analiza el término de empoderamiento, y las experiencias en la vida de mujeres líderes políticas mexicanas, con el fin de determinar cuáles de estas experiencias influyeron  en el  proceso de empoderamiento. Se analiza como las mujeres mismas vivieron ese proceso y que sucesos fueron comunes a ellas, en especial desde los ejes de análisis de educación, crianza, ambiente familiar, religión, entre otras. De acuerdo a lo esperado, se encontró que las mujeres entrevistadas, a pesar de ser de diversos orígenes comparten experiencias que las ayudaron o bien dificultaron su proceso de empoderamiento.

  7. EXPERIENCIAS DE GUERRA DESDE LA VOZ DE LAS MUJERES

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    Elsa Blair

    2003-01-01

    Full Text Available El articulo recoge algunas reflexiones en tormo al trabajode campo realizado con mujeres excombatientes de diversos grupos armados colombianos en el marco de la investigación Mujeres en tiempos de guerra: una mirada a lo femenino en el contexto de los grupos armados colombianos. A partir de una concepción de la guerra como construcción cultural, las autoras interrogan los efectos de la misma sobre su identidad femenina, esto es, lo que la guerra ha representado para ellas como mujeres y los efectos que ha tenido en términos de su identidad genérica. Tras una reflexión inicia en torno a los desafíos éticos planteados por el trabajo de campo, las autoras abordan la problemática de la identidad de género a través de dos vías: por una parte, los campos o "nudos¿ temáticos que amarran las narraciones de mujeres entrevistadas -la familia, la maternidad y los hijos, las relaciones con los "otros", las experiencias de muerte y el dolor de la guerra-; y por otra, la forma particular en que ellas construyen sus relatos sobre su experiencia como combatientes. Por último, a partir de esa mirada analítica sobre la manera como estas mujeres han vivido y significado su experiencia como guerreras, las autoras plantean, algunas conclusiones preliminares en torno a dicha problemática.

  8. ESTUDIO DE LA DIGESTION HUMANA CON ALUMNOS CON DIFICULTADES DE APRENDIZAJE

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    Mª Begoña Carretero Gómez

    2009-01-01

    Full Text Available En esta experiencia se han seleccionado una serie de actividades relacionadas con la digestión con el fin de lograr una reestructuración de ideas y cambios conceptuales, y así con la conseguir que el alumnado aprenda a construir sus propios conocimientos acerca de cómo y donde se dan los procesos de digestión necesarios para la nutrición del organismo. El trabajo se ha llevado a cabo con alumnos de 3º de Educación Secundaria Obligatoria, pertenecientesal programa de diversificación curricular. Hemos querido hacer la ciencia más cercana para que comprendan que algunos procesos tienen su explicación científica y que la ciencia forma parte de nuestro día a día, fomentando el interés del estudiante así como su implicación en el proceso de enseñanza-aprendizaje. Por ello hemos trabajado a base de pequeñas investigaciones, donde es el alumno el que marca su ritmo de trabajo, investiga y hace sus aportaciones. Han aprendido a trabajar de una forma meticulosa donde el rigor esfundamental, contagiándose del afán investigador de manera que al realizar las experiencias se han aproximado al trabajo científico a la vez que aclaran y reestructuran conocimientos.

  9. Experiencia exploratoria con Maestros de Apoyo del Plan Ceibal (Uruguay como insumo para la creación de un Modelo de Alfabetización en Información

    Directory of Open Access Journals (Sweden)

    Lucía Baica Preyones

    2016-01-01

    Full Text Available El artículo presenta los resultados obtenidos en la experiencia exploratoria de prácticas de búsqueda, selección y evaluación de fuentes de información con Maestros de Apoyo del Plan Ceibal (MAC (Uruguay. La experiencia se realizó dentro del marco del Proyecto “Alfabetización en información y competencias lectoras” que se lleva adelante en el Programa de Desarrollo Académico de la Información y la Comunicación (PRODIC de la Facultad de Información y Comunicación (FIC de la Universidad de la República (UdelaR. Se trabajó con 20 maestros de escuelas públicas de la zona oeste de la ciudad de Montevideo en modalidad de taller, observando el proceso de búsqueda, selección y evaluación de la información realizado por los mismos a partir de una consigna que tomaba como base de la búsqueda temas de actualidad. El objetivo de la experiencia fue sensibilizar a los maestros sobre la importancia de la alfabetización en información y conocer primariamente sus comportamientos en cuanto al vínculo con la información. Los resultados de la experiencia fueron volcados a la construcción de un Modelo de alfabetización en información para el Plan Ceibal. The article presents the results obtained in an exploratory experiment of research, selection and evaluation of information sources. These practices were made with the Plan Ceibal (MAC support teachers (Uruguay. The experiment was carried out within the framework of the “information and reading literacy” program, which is carried out in the Academic Development Program on Information and Communication (PRODIC of the Information and Comunicación Faculty (FIC of the Universidad de la República (UdelaR. The research worked with 20 teachers who came from state schools in the western district of Montevideo and who developed the project in a workshop mode, observing the research, selection and evaluation of the information. These processes were made by the teachers themselves by

  10. El diseño para estímulo a experiencias territoriales con el arte

    Directory of Open Access Journals (Sweden)

    Leandro Miletto Tonetto

    2015-06-01

    Full Text Available Porto Alegre, capital de Rio Grande do Sul, se promueve como un destino cultural para la comunidad local y para los visitantes. Algunos de sus proyectos conocidos son Porto Alegre em Cena, Porto Verão Alegre y Serenata Iluminada, además de la Bienal de Artes Visuales del Mercosur, que tuvo su 9ª edición el año de 2013. En ese contexto, la investigación desarrollada visó comprender cómo proyectar estímulos que faciliten a creación de vínculos de los ciudadanos con el arte, en la ciudad de Porto Alegre, partiendo de la experiencia de la 9ª Bienal del Mercosur. Se realizó una investigación de naturaleza exploratória, sobre la experiencia de personas que tienen recurrencia en visitación a la Bienal, por medio de veinte entrevistas en profundidad. Los resultados fueron discutidos a partir de sus potencialidades para fomentar proyectos de diseño aplicado al territorio y ratificaron el potencial que el espacio de la ciudad tiene para estimular la conexión entre personas y arte, lo que puede ser trabajado por instituciones diversas, a partir de intervenciones planeadas.  Además de eso, se observó que el territorio, como objeto projetual de diseño, puede ofrecer no sólo un espacio adecuado para las personas, sino también facilitar la dinámica social que acontece en él. En ese escenario, el factor interacción que se establece entre el territorio, el arte y las personas facilita el desarrollo del vínculo emocional entre la Bienal y los habitantes de la ciudad. La ciudad, como metrópoli permeada por el arte en el periodo de la Bienal, es un fenómeno único, a ser observado. Las conclusiones apuntan que, aunque algunos elementos parecen ser independientes de la ciudad, otros, como el uso de sus espacios característicos, son circunscritos a aspectos marcadamente locales.

  11. La mujer obesa de los sectores populares: Una experiencia de trabajo en salud

    OpenAIRE

    Uribe Jaramillo, Tulia María

    1994-01-01

    El artículo describe el desarrollo de una experiencia de trabajo con un grupo de cincuenta mujeres obesas, residentes en un sector popular del municipio de Medellín. Se analiza la condición de género de estas mujeres desde las dimensiones física, afectiva, participativa y moral y su relacion con la obesidad y con algunas prácticas cotidianas asociadas con la salud. El análisis sirve de fundamento para el diseño de una propuesta de carácter integral, con base en un trabajo conjunto de reflexió...

  12. Intradisciplinariedad e Interdisciplinariedad en la adquisición de competencias: estudio de una experiencia de aprendizaje cooperativo

    Directory of Open Access Journals (Sweden)

    Pere Lavega

    2013-01-01

    Full Text Available Los objetivos planteados en este estudio fueron: analizar el nivel de adquisición de las competencias, estudiar el desarrollo del trabajo en equipo y el proceso de interacción profesor – alumno desde ambas perspectivas, así como desvelar el grado de satisfacción expresado por discentes y docentes en una experiencia pedagógica intradisciplinar e interdisciplinar. Esta experiencia se realizó con 130 estudiantes del grado en ciencias de la actividad física y del deporte (INEFC, Universidad de Lleida, con la implicación de seis profesores de tres asignaturas de primer curso que compartían competencias específicas y transversales. Los alumnos debían resolver un problema mediante el aprendizaje cooperativo. Los resultados muestran que esta experiencia merece una valoración positiva en la adquisición de competencias específicas y transversales.

  13. Palimpsestos con Hélène Cixous: experimentos consigo mismo

    Directory of Open Access Journals (Sweden)

    Alberto Bejarano Hernández

    2017-01-01

    Full Text Available Nuestra reflexión se interesa por la(s lengua(s habitadas por la es - critora y filósofa Héléne Cixous a través de nuestra experiencia en sus clases y en la lectura continua de sus obras de carácter híbrido y abierto. Se trata de un diálogo que desarrollamos con su obra in- cluyendo nuestra propia experiencia con la escritura en forma de palimpsesto en el que tejemos sentidos y sensaciones de la palabra y sus resonancias.

  14. The clinical use of myocardial gated SPECT imaging with 99TcmN-NOEt

    International Nuclear Information System (INIS)

    Li Sijin; Hu Guang; Liu Jianzhong; Tian Mei; Li Xianfeng; Zhang Wanchun; Wang Jin

    2002-01-01

    Objective: To evaluate the clinical value of 99 Tc m N-NOEt myocardial perfusion imaging comparing with 99 Tc m -MIBI. Methods: Twenty patients (pts) were divided into 2 groups. Group 1 (G1), left ventricular ejection fraction (LVEF) ≥ 50%, 13 pts, the mean age was (49.9 +- 14.7) years. Group 2 (G2), LVEF 0.05 vs G1). All the pst underwent gated SPECT imaging at 30 and 120 min after injection of 925 MBq 99 Tc m N-NOEt at rest, and the heart to lung (H/L) activity ratio was calculated. Of the 6 pts in G2 and 1 pt in G1 underwent the 99 Tc m -MIBI imaging within 3 days to the former imaging at 120 min after 99 Tc m -MIBI injection under the same condition as at 99 Tc m N-NOEt imaging. The left ventricles of the 7 pts were divided into 63 segments with 9 segments for each, and the four-point scoring system was used to evaluate the tracer uptake in the segments. Results: The H/L ratio was 1.47 +- 0.47 and 1.59 +- 0.53 (P > 0.50) respectively in G1 and was 0.72 +- 0.11 and 0.89 +- 0.11 (P 99 Tc m N-NOEt and 99 Tc m -MIBI for the presence of defects was 93.65%, Kappa +- s = 0.87 +- 0.12. The mean score was 2.0 +- 0.84 (MIBI) and 2.38 +- 0.84 (NOEt) respectively (P > 0.05). Conclusions: 1) If the lung uptake of 99 Tc m N-NOET showed higher, it suggested that the left ventricular function was poor. 2) The results of LVEF, EDV and ESV were accordant between MIBI and NOEt. 3) The extent and intensity of myocardial defect with NOEt imaging was more severe than that with MIBI

  15. El modelo de servicio de un MBA con enfoque humanístico

    Directory of Open Access Journals (Sweden)

    Ernesto Barrera Duque

    2011-06-01

    Full Text Available Este artículo de investigación tiene como objetivo establecer los elementos fundamentales de la experiencia del estudiante MBA en el programa de una institución educativa colombiana. Mediante la combinación del análisis narrativo y la teoría fundamentada, ambos dentro de la modalidad de metodología cualitativa, se hallaron categorías fundamentales en la experiencia de servicio. La interacción con los profesores, la interacción con los directores de estudio, el contexto organizacional de la institución educativa, la interacción con otros participantes y el diseño del programa centrado en el participante, fueron los inductores de la experiencia. Además, se encontró que el método del caso era un mediador importante para verter una experiencia de carácter práctico. Finalmente, los elementos de impacto en el estudiante fueron el desarrollo de habilidades directivas y la transformación personal integral. El enfoque humanístico, imbuido en todas las categorías, sirvió de pliegue entre ellas, indicando que este elemento es consistente y potencia la formación orientada a mejorar el desempeño laboral y personal de los participantes. Además, este enfoque, que es evidente en la experiencia, es valorado por los estudiantes.

  16. Educación popular y nutrición infantil: experiencia de trabajo con mujeres en una zona rural de México

    Directory of Open Access Journals (Sweden)

    Luz Arenas-Monreal

    1999-04-01

    Full Text Available OBJETIVO: Se realizó una intervención comunitaria bajo la estrategia de promoción de la salud, con el objetivo de desarrollar un programa de educación para la salud con mujeres. MÉTODOS: Se analizó la metodología de educación popular; con la finalidad de generar procesos organizativos y de participación social que mejoren la nutrición y sobrevivencia infantil. RESULTADOS: Los principales resultados, se relacionan con la generación de procesos autogestivos, la conformación de un grupo de promotoras de salud que han impulsado la organización de las mujeres enfocando su trabajo a mejorar la nutrición infantil y la salud familiar. Las promotoras han tomado en sus manos el programa de vigilancia epidemiológica en nutrición infantil y en conjunto con las mujeres han emprendido una serie de acciones para mejorar la nutrición de los niños y los porcentajes de desnutrición en los niños que participan en el programa de nutrición infantil han iniciado un descenso (64% a 62%. CONCLUSIONES: Los programas de nutrición infantil tienen mayores posibilidades de éxito en la medida que logran involucrar a la población en la resolución de esta problemática, eso es posible cuando se utiliza una metodología que propicie la participación de los individuos y se generen espacios que les permitan realizar una práctica transformadora de su realidad. La metodología de la educación popular proporciona las pautas en ese sentido. Es necesario continuar ampliando las experiencias educativas en educación para la salud con este tipo de metodología.

  17. Educación popular y nutrición infantil: experiencia de trabajo con mujeres en una zona rural de México

    Directory of Open Access Journals (Sweden)

    Arenas-Monreal Luz

    1999-01-01

    Full Text Available OBJETIVO: Se realizó una intervención comunitaria bajo la estrategia de promoción de la salud, con el objetivo de desarrollar un programa de educación para la salud con mujeres. MÉTODOS: Se analizó la metodología de educación popular; con la finalidad de generar procesos organizativos y de participación social que mejoren la nutrición y sobrevivencia infantil. RESULTADOS: Los principales resultados, se relacionan con la generación de procesos autogestivos, la conformación de un grupo de promotoras de salud que han impulsado la organización de las mujeres enfocando su trabajo a mejorar la nutrición infantil y la salud familiar. Las promotoras han tomado en sus manos el programa de vigilancia epidemiológica en nutrición infantil y en conjunto con las mujeres han emprendido una serie de acciones para mejorar la nutrición de los niños y los porcentajes de desnutrición en los niños que participan en el programa de nutrición infantil han iniciado un descenso (64% a 62%. CONCLUSIONES: Los programas de nutrición infantil tienen mayores posibilidades de éxito en la medida que logran involucrar a la población en la resolución de esta problemática, eso es posible cuando se utiliza una metodología que propicie la participación de los individuos y se generen espacios que les permitan realizar una práctica transformadora de su realidad. La metodología de la educación popular proporciona las pautas en ese sentido. Es necesario continuar ampliando las experiencias educativas en educación para la salud con este tipo de metodología.

  18. Development and optimization of SPECT gated blood pool cluster analysis for the prediction of CRT outcome

    Energy Technology Data Exchange (ETDEWEB)

    Lalonde, Michel, E-mail: mlalonde15@rogers.com; Wassenaar, Richard [Department of Physics, Carleton University, Ottawa, Ontario K1S 5B6 (Canada); Wells, R. Glenn; Birnie, David; Ruddy, Terrence D. [Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7 (Canada)

    2014-07-15

    Purpose: Phase analysis of single photon emission computed tomography (SPECT) radionuclide angiography (RNA) has been investigated for its potential to predict the outcome of cardiac resynchronization therapy (CRT). However, phase analysis may be limited in its potential at predicting CRT outcome as valuable information may be lost by assuming that time-activity curves (TAC) follow a simple sinusoidal shape. A new method, cluster analysis, is proposed which directly evaluates the TACs and may lead to a better understanding of dyssynchrony patterns and CRT outcome. Cluster analysis algorithms were developed and optimized to maximize their ability to predict CRT response. Methods: About 49 patients (N = 27 ischemic etiology) received a SPECT RNA scan as well as positron emission tomography (PET) perfusion and viability scans prior to undergoing CRT. A semiautomated algorithm sampled the left ventricle wall to produce 568 TACs from SPECT RNA data. The TACs were then subjected to two different cluster analysis techniques, K-means, and normal average, where several input metrics were also varied to determine the optimal settings for the prediction of CRT outcome. Each TAC was assigned to a cluster group based on the comparison criteria and global and segmental cluster size and scores were used as measures of dyssynchrony and used to predict response to CRT. A repeated random twofold cross-validation technique was used to train and validate the cluster algorithm. Receiver operating characteristic (ROC) analysis was used to calculate the area under the curve (AUC) and compare results to those obtained for SPECT RNA phase analysis and PET scar size analysis methods. Results: Using the normal average cluster analysis approach, the septal wall produced statistically significant results for predicting CRT results in the ischemic population (ROC AUC = 0.73;p < 0.05 vs. equal chance ROC AUC = 0.50) with an optimal operating point of 71% sensitivity and 60% specificity. Cluster

  19. Development and optimization of SPECT gated blood pool cluster analysis for the prediction of CRT outcome

    International Nuclear Information System (INIS)

    Lalonde, Michel; Wassenaar, Richard; Wells, R. Glenn; Birnie, David; Ruddy, Terrence D.

    2014-01-01

    Purpose: Phase analysis of single photon emission computed tomography (SPECT) radionuclide angiography (RNA) has been investigated for its potential to predict the outcome of cardiac resynchronization therapy (CRT). However, phase analysis may be limited in its potential at predicting CRT outcome as valuable information may be lost by assuming that time-activity curves (TAC) follow a simple sinusoidal shape. A new method, cluster analysis, is proposed which directly evaluates the TACs and may lead to a better understanding of dyssynchrony patterns and CRT outcome. Cluster analysis algorithms were developed and optimized to maximize their ability to predict CRT response. Methods: About 49 patients (N = 27 ischemic etiology) received a SPECT RNA scan as well as positron emission tomography (PET) perfusion and viability scans prior to undergoing CRT. A semiautomated algorithm sampled the left ventricle wall to produce 568 TACs from SPECT RNA data. The TACs were then subjected to two different cluster analysis techniques, K-means, and normal average, where several input metrics were also varied to determine the optimal settings for the prediction of CRT outcome. Each TAC was assigned to a cluster group based on the comparison criteria and global and segmental cluster size and scores were used as measures of dyssynchrony and used to predict response to CRT. A repeated random twofold cross-validation technique was used to train and validate the cluster algorithm. Receiver operating characteristic (ROC) analysis was used to calculate the area under the curve (AUC) and compare results to those obtained for SPECT RNA phase analysis and PET scar size analysis methods. Results: Using the normal average cluster analysis approach, the septal wall produced statistically significant results for predicting CRT results in the ischemic population (ROC AUC = 0.73;p < 0.05 vs. equal chance ROC AUC = 0.50) with an optimal operating point of 71% sensitivity and 60% specificity. Cluster

  20. La gestión participativa en la construcción del hábitat residencial. Experiencia con 54 familias dispersas de Villa El Libertador

    Directory of Open Access Journals (Sweden)

    Mónica Martínez Rusconi

    2001-01-01

    Full Text Available Desde 1995, se viene incursionando sobre la temática de la participación en el diseño y materialización del hábitat para población de escasos recursos. A través de sucesivos proyectos de investigación otorgados por la Secretaría de Extensión Universitaria (1995 y el Consejo de Investigaciones Científicas y Tecnológicas de la provincia de Córdoba (Martínez Rusconi 1996-1999, y en el marco de la Universidad Nacional de Córdoba, Facultad de Arquitectura, Urbanismo y Diseño, se ha consolidado una basta experiencia en el medio local, acercándonos a la comunidad, verdadero protagonista del ejercicio participativo. Una de las experiencias desarrolladas se lleva a cabo con un grupo de población dispersa –54 familias- de Villa El Libertador. La participación como mecanismo de gestión ha permitido el desarrollo de acciones tendientes a abordar la problemática habitacional de este grupo humano, como son la selección y compra de tierra urbana, y la elaboración y gestión del proyecto de vivienda. La obtención de tercera mención, dentro del concurso “La participación en el planeamiento y diseño del hábitat popular” (Cyted 1998, avala las experiencias, métodos y reflexiones abordados dentro de esta línea investigativa.

  1. Optimal left ventricular lead position assessed with phase analysis on gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Boogers, Mark J.; Chen, Ji; Garcia, Ernest V.; Bommel, Rutger J. van; Borleffs, C.J.W.; Schalij, Martin J.; Wall, Ernst E. van der; Bax, Jeroen J.; Dibbets-Schneider, Petra; Hiel, Bernies van der; Younis, Imad Al

    2011-01-01

    The aim of the current study was to evaluate the relationship between the site of latest mechanical activation as assessed with gated myocardial perfusion SPECT (GMPS), left ventricular (LV) lead position and response to cardiac resynchronization therapy (CRT). The patient population consisted of consecutive patients with advanced heart failure in whom CRT was currently indicated. Before implantation, 2-D echocardiography and GMPS were performed. The echocardiography was performed to assess LV end-systolic volume (LVESV), LV end-diastolic volume (LVEDV) and LV ejection fraction (LVEF). The site of latest mechanical activation was assessed by phase analysis of GMPS studies and related to LV lead position on fluoroscopy. Echocardiography was repeated after 6 months of CRT. CRT response was defined as a decrease of ≥15% in LVESV. Enrolled in the study were 90 patients (72% men, 67±10 years) with advanced heart failure. In 52 patients (58%), the LV lead was positioned at the site of latest mechanical activation (concordant), and in 38 patients (42%) the LV lead was positioned outside the site of latest mechanical activation (discordant). CRT response was significantly more often documented in patients with a concordant LV lead position than in patients with a discordant LV lead position (79% vs. 26%, p<0.01). After 6 months, patients with a concordant LV lead position showed significant improvement in LVEF, LVESV and LVEDV (p<0.05), whereas patients with a discordant LV lead position showed no significant improvement in these variables. Patients with a concordant LV lead position showed significant improvement in LV volumes and LV systolic function, whereas patients with a discordant LV lead position showed no significant improvements. (orig.)

  2. Brain SPECT

    International Nuclear Information System (INIS)

    Feistel, H.

    1991-01-01

    Brain SPECT investigations have gained broad acceptance since the introduction of the lipophilic tracer Tc-99m-HMPAO. Depending on equipment and objectives in different departments, the examinations can be divided into three groups: 1. Under normal conditions and standardised patient preparation the 'rest' SPECT can be performed in every department with a tomographic camera. In cerebrovascular disease there is a demand for determination of either the perfusion reserve in reversible ischemia or prognostic values in completed stroke. In cases of dementia, SPECT may yield useful results according to differential diagnosis. Central cerebral system involvement in immunologic disease may be estimated with higher sensitivity than in conventional brain imaging procedures. In psychiatric diseases there is only a relative indication for brain SPECT, since results during recent years have been contradictory and may be derived only in interventional manner. In brain tumor diagnostics SPECT with Tl-201 possibly permits grading. In inflammatory disease, especially in viral encephalitis, SPECT may be used to obtain early diagnosis. Normal pressure hydrocephalus can be distinguished from other forms of dementia and, consequently, the necessity for shunting surgery can be recognised. 2. In departments equipped for emergency cases an 'acute' SPECT can be performed in illnesses with rapid changing symptoms such as different forms of migraine, transient global amnesia, epileptic seizures (so-called 'ictal SPECT') or urgent forms like trauma. 3. In cooperation with several departments brain SPECT can be practised as an interventional procedure in clinical and in scientific studies. (orig./MG) [de

  3. Spatiotemporal processing of gated cardiac SPECT images using deformable mesh modeling

    International Nuclear Information System (INIS)

    Brankov, Jovan G.; Yang Yongyi; Wernick, Miles N.

    2005-01-01

    In this paper we present a spatiotemporal processing approach, based on deformable mesh modeling, for noise reduction in gated cardiac single-photon emission computed tomography images. Because of the partial volume effect (PVE), clinical cardiac-gated perfusion images exhibit a phenomenon known as brightening--the myocardium appears to become brighter as the heart wall thickens. Although brightening is an artifact, it serves as an important diagnostic feature for assessment of wall thickening in clinical practice. Our proposed processing algorithm aims to preserve this important diagnostic feature while reducing the noise level in the images. The proposed algorithm is based on the use of a deformable mesh for modeling the cardiac motion in a gated cardiac sequence, based on which the images are processed by smoothing along space-time trajectories of object points while taking into account the PVE. Our experiments demonstrate that the proposed algorithm can yield significantly more-accurate results than several existing methods

  4. Rentabilidad de hoteles boutique explicada desde la experiencia memorable

    Directory of Open Access Journals (Sweden)

    Driselda Patricia Sánchez Aguirre

    2017-01-01

    Full Text Available Los hoteles boutique representan una tendencia en el sector de alojamiento, son organizaciones de lujo, con pocas habitaciones, que surgen a partir de las preferencias de viajeros irónicos y exigentes, aquellos que buscan un espacio en el que converja el escape de la realidad, pero al mismo tiempo puedan sentirse en casa. Aunque varios hoteles boutique son empresas pequeñas e incluso familiares, los indicadores reportados del segmento en México muestran organizaciones rentables en términos de la industria. El principal objetivo de este artículo es explicar la rentabilidad de estas organizaciones desde una perspectiva teórica, considerando la teoría de economía de la experiencia y su complementariedad con la teoría de recursos y capacidades. La reflexión final hace alusión al servicio superior, la capacidad para sorprender a sus huéspedes y la creatividad de los recursos humanos como los principales factores en la generación de experiencias memorables y que gracias a la reputación que construyen, contribuyen a la rentabilidad de estas organizaciones. |

  5. Clinical application of heart rate-synchronized myocardial SPECT with {sup 99m}Tc-labeled imaging agents for myocardial blood flow

    Energy Technology Data Exchange (ETDEWEB)

    Nishimura, Tsunehiko; Uehara, Toshiisa; Fukuchi, Kazuki; Tsujimura, Eiichiro; Hasegawa, Shinji; Ito, Yasushi; Hashimoto, Katsuji; Matsuda, Shinichi; Yutani, Kenji [Osaka Univ., Suita (Japan). Biomedical Research Center

    1996-11-01

    Application of gated SPECT to assess multiple heart functions simultaneously in authors` facility was reported. The myocardial SPECT at rest was performed 1 hr after intravenous administration of 740 MBq of {sup 99m}Tc-sestamibi with Toshiba 3-detector type gamma camera GCA9300/HG. R wave monitored by ECG was used as a trigger to record images of 360deg direction (90 sec/6deg direction, 20 directions x 3). Data were processed by Toshiba GMS-5500A or Hitachi-Medico RW3000. Percent CI (count increase at a myocardial region) was calculated by =(ES-ED)=/ED x 100, where ES and ED were computed by circumferential profile analysis of reconstruction images at the end-systole and end-diastole stages, respectively. Left ventricular ejection fraction was calculated from %AC (area change between areas of left ventricle at end-systolic and -diasystolic stages). Ventricular wall-motion was assessed by bullet display of the gated SPECT images. The present procedure is expected to be widely used as a routine test of the myocardial functions and is beneficial from a viewpoint of cost/performance. (K.H.)

  6. Instrumentos para la evaluación de experiencias Flipped Learning en el aula de primaria

    OpenAIRE

    Núñez Marín, Anunciación

    2015-01-01

    Instrumentos de evaluación de experiencia de trabajo en el aula con la metodología Flipped Classroom. Se incluyen tres instrumentos: registro de observación, cuestionario familias, cuestionario alumnos.

  7. Postoperative Functional Outcome After Off-Pump Versus On-Pump Coronary Artery Bypass Grafting Using Gated Myocardial SPECT: A Comparison by Propensity Score Analysis

    International Nuclear Information System (INIS)

    Lee, Jong Jin; Paeng, Jin Chul; Lee, Dong Soo; Kim, Ki Bong; Chung, June Key; Lee, Myung Chul; Kang, Won Jun

    2010-01-01

    We evaluated the short-term and mid-term differences in perfusion and function after off-pump and on-pump coronary artery bypass grafting (CABG) using gated myocardial single photon emission computed tomography. A total of 70 patients with coronary artery disease who underwent CABG were included based on the propensity score matching results from 165 patients. Thirty-five patients underwent off-pump and 35 patients on-pump CABG. Rest 201 TI/dipyridamole stress 99m Tc-methoxyisobutylisonitrile gated single photon emission computed thermographs were performed preoperatively and postoperatively at short-term (103±23 days after surgery) and mid-term follow-up (502±111 days after surgery). Changes in left ventricular ejection fraction, end systolic volume, stress and rest segmental perfusion, and segmental wall thickening were compared between the two groups. The segments with preoperative rest 201 T1 uptake under 60% of maximum uptake were included in the segmental analysis. Left ventricular ejection fraction (P=0.001) and end systolic volume (P=0.008) showed significant improvement in both groups. There were no significant short-term and mid-term differences between the two groups in terms of left ventricular ejection fraction (P=0.309) and end systolic volume (P=0.938). Likewise, segmental rest (P=0.178) and stress perfusion (P=0.071), and systolic wall thickening (P=0.241) showed significant improvement in both groups with similar time courses. Off-pump CABG resulted in significant improvements in left ventricular ejection fraction, end systolic volume, and regional myocardial perfusion and function that are comparable to on-pump CABG at short-term and mid-term. Gated myocardial SPECT successfully revealed that off-pump CABG is as good as on-pump CABG from the viewpoint of myocardial perfusion and function.

  8. Experiencias de adolescentes embarazadas en control prenatal

    Directory of Open Access Journals (Sweden)

    Hilda Evelia Prías-Vanegas

    2009-01-01

    Full Text Available Objetivo: describir e interpretar las experiencias relacionadas con los sentimientos e ideas experimentados por las adolescentes al conocer su estado de embarazo. Método: se trabajó con un grupo de 22 adolescentes de instituciones públicas de I nivel de salud de Sincelejo, Colombia. El estudio, realizado en 2005, se abordó desde un enfoque cualitativo, con información recogida en entrevistas personales, grabadas con consentimiento de las jóvenes. Resultados: el embarazo genera en la adolescente sentimientos de displacer relacionados con miedo, tristeza, dolor, sufrimiento, culpa, vergüenza y decepción, acompañados de ideas de negación, evasión, duda, arrepentimiento y deseos de abortar, los cuales no aparecen cuando la adolescente cuenta con el apoyo de su compañero sentimental o el de sus padres. Conclusión: las adolescentes necesitan apoyo, comprensión y ayuda, dado que están más sensibles, lábiles, inseguras y con baja autoestima, situación que requiere que el equipo de salud desarrolle y muestre competencias en el área humanística, acercamiento personal, empatía y trato humanizado e individualizado en la atención de la población de adolescentes embarazadas.

  9. Favoreciendo el acceso a la web: experiencias con usuarios mayores de la región patagónica

    Directory of Open Access Journals (Sweden)

    Diego Vilte

    2014-09-01

    Full Text Available En esta nueva era donde las TICs y la Web evolucionan rápidamente es de vital importancia que estos recursos puedan ser utilizados por todos los usuarios y que no existan barreras que dificulten trabajar con ellos. La accesibilidad y usabilidad, entre otros atributos de calidad, son propiedades que deben estar presentes en estas tecnologías para que puedan ser accedidas con éxito por todos los ciudadanos. Pero, la diversidad humana propone un gran variedad de usuarios Web con diferentes características y problemáticas. Por ejemplo, usuarios con algún tipo de discapacidad (problemas visuales, de motricidad y cognitivos; usuarios comprendidos en diferentes rangos de edades (adultos, adultos mayores, jóvenes y niños, usuarios pertenecientes a diferentes culturas (costumbres e idiomas, etc. También es importante considerar el hecho de que nadie está exento a lo largo de su vida de sufrir algún tipo de discapacidad permanente (o temporal que dificulte el acceso e interación con estas tecnologías y la Web.Numerosos han sido los esfuerzos de los grupos de investigación para contribuir con propuestas a la Usabilidad de la Web. También, desde 1999, año en que se presentan las primeras recomendaciones sobre Accesibilidad Web del consorcio W3C, diferentes organizaciones han propuesto estándares y guías para contribuir a una Web más accesible. Todos estas propuestas y documentos se pueden aplicar para concebir y desarrollar sitios Web nuevos, cómo así también para revisar y mejorar la Accesibilidad de los sitios Web existentes. Si embargo, aportar soluciones para ofrecer sitios Web más accesibles a los diferentes perfiles de usuario, no es un problema trivial.En este trabajo, presentamos dos experiencias con usuarios adultos mayores, para determinar y proponer mejoras que se ajusten a las necesidades de este importante y creciente grupo de usuarios Web. Nuestras propuestas surgen del trabajo conjunto entre los docentes/ investigadores

  10. Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Ching-Chu; Cheng, Mei-Fang; Tzen, Kai-Yuan; Yen, Ruoh-Fang [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Nuclear Medicine, Taipei (China); Wu, Vin-Cent; Wu, Kwan-Dun [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Internal Medicine, Taipei (China); Liu, Kao-Lang [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Medical Imaging, Taipei (China); Lin, Wei-Chou [National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Pathology, Taipei (China); Collaboration: the TAIPAI Study Group

    2014-07-15

    Primary aldosteronism (PA), characterized by an excessive production of aldosterone, affects 5-13 % of patients with hypertension. Accurate strategies are needed for the timely diagnosis of PA to allow curability and prevention of excessive cardiovascular events and related damage. This study aimed to evaluate the usefulness of semiquantification of {sup 131}I-6β-iodomethyl-norcholesterol (NP-59) single photon emission computed tomography (SPECT)/CT in differentiating aldosterone-producing adenoma (APA) from idiopathic adrenal hyperplasia (IAH) and in predicting clinical outcomes after adrenalectomy. We retrospectively reviewed 49 PA patients who had undergone adrenalectomy after NP-59 SPECT/CT within 1 year. A conventional visual scale (VS) and two semiquantitative parameters generated from SPECT/CT, adrenal to liver ratio (ALR) and lesion to contralateral ratio of bilateral adrenal glands (CON), with cutoff values calculated by receiver-operating characteristic (ROC) analysis, were compared with pathology results and postsurgical outcomes to determine the accuracy. An ALR cutoff of 1.84 and a CON cutoff of 1.15 showed an ability to distinguish adenoma from hyperplasia similar to VS (p = 0.2592 and 0.1908, respectively). An ALR cutoff of 2.28 and a CON cutoff of 1.11 yielded the highest sensitivity and specificity to predict postsurgical outcomes, and an ALR of 2.28 had an ability superior to VS (p = 0.0215), while a CON of 1.11 did not (p = 0.1015). Patients with either ALR or CON greater than the cutoff had a high probability of positive postsurgical outcomes (n = 36/38), while patients with both ALR and CON less than the cutoff had a low probability of positive postsurgical outcomes (n = 2/11). Semiquantification of NP-59 scintigraphy has an ability similar to VS in differentiating APA from IAH, but an excellent ability to predict postsurgical outcomes of adrenalectomy. An ALR or CON greater than the cutoff strongly suggests benefits from adrenalectomy, and

  11. Prognostic value of semiquantification NP-59 SPECT/CT in primary aldosteronism patients after adrenalectomy

    International Nuclear Information System (INIS)

    Lu, Ching-Chu; Cheng, Mei-Fang; Tzen, Kai-Yuan; Yen, Ruoh-Fang; Wu, Vin-Cent; Wu, Kwan-Dun; Liu, Kao-Lang; Lin, Wei-Chou

    2014-01-01

    Primary aldosteronism (PA), characterized by an excessive production of aldosterone, affects 5-13 % of patients with hypertension. Accurate strategies are needed for the timely diagnosis of PA to allow curability and prevention of excessive cardiovascular events and related damage. This study aimed to evaluate the usefulness of semiquantification of 131 I-6β-iodomethyl-norcholesterol (NP-59) single photon emission computed tomography (SPECT)/CT in differentiating aldosterone-producing adenoma (APA) from idiopathic adrenal hyperplasia (IAH) and in predicting clinical outcomes after adrenalectomy. We retrospectively reviewed 49 PA patients who had undergone adrenalectomy after NP-59 SPECT/CT within 1 year. A conventional visual scale (VS) and two semiquantitative parameters generated from SPECT/CT, adrenal to liver ratio (ALR) and lesion to contralateral ratio of bilateral adrenal glands (CON), with cutoff values calculated by receiver-operating characteristic (ROC) analysis, were compared with pathology results and postsurgical outcomes to determine the accuracy. An ALR cutoff of 1.84 and a CON cutoff of 1.15 showed an ability to distinguish adenoma from hyperplasia similar to VS (p = 0.2592 and 0.1908, respectively). An ALR cutoff of 2.28 and a CON cutoff of 1.11 yielded the highest sensitivity and specificity to predict postsurgical outcomes, and an ALR of 2.28 had an ability superior to VS (p = 0.0215), while a CON of 1.11 did not (p = 0.1015). Patients with either ALR or CON greater than the cutoff had a high probability of positive postsurgical outcomes (n = 36/38), while patients with both ALR and CON less than the cutoff had a low probability of positive postsurgical outcomes (n = 2/11). Semiquantification of NP-59 scintigraphy has an ability similar to VS in differentiating APA from IAH, but an excellent ability to predict postsurgical outcomes of adrenalectomy. An ALR or CON greater than the cutoff strongly suggests benefits from adrenalectomy, and both

  12. El Compromiso de las Bibliotecas Públicas con la diversidad sexual: análises de las iniciativas y experiencias desarrolladas en España y Portugal

    OpenAIRE

    Frías, José Antonio; Oliveira, Rosa

    2015-01-01

    Se analizan las principales experiencias desarrolladas, por las bibliotecas públicas en España y Portugal orientadas a combatir la exclusión de las personas LGTB y la homofobia social, vinculadas casi siempre a la celebración del 28 de junio, Día del Orgullo Lésbico, Gay y Transexual, y orientadas a la incorporación de fondos de temática LGTB a las colecciones, elaboración de guías de lectura y colaboración con colectivos LGTB en la organización de actividades de distinta índole (conferencias...

  13. Cáncer de piel: barreras de acceso e itinerario burocrático. una experiencia colombiana

    OpenAIRE

    Sánchez Vanegas, Guillermo; De la Hoz Restrepo, Fernando; Abadía, Cesar; Nova, John; López, Emma

    2013-01-01

    Objetivo Describir y comprender de forma integral las experiencias que han vivido personas con cáncer de piel no melanoma en su lucha por recuperar la salud, descifrando el itinerario que recorren en busca de atención, describiendo las relaciones con el sistema de salud, estableciendo la tasa de tutelas y el porcentaje de servicios negados, y documentando los determinantes relacionados con el diagnóstico oportuno.Métodos Se realizó un estudio con metodología mixta desde la perspectiva combina...

  14. The current status of SPECT or SPECT/CT in South Korea

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Ik Dong; Choi, Eun Kyung; Chung, Yong An [Dept. of Radiology, Incheon Saint Mary' s HospitalThe Catholic University of Korea, Incheon (Korea, Republic of)

    2017-06-15

    The first step to nuclear medicine in Korea started with introduction of the gamma camera in 1969. Although planar images with the gamma camera give important functional information, they have the limitations that result from 2-dimensional images. Single-photon emission computed tomography (SPECT) due to its 3-dimensional image acquisition is superior to earlier planar gamma imaging in image resolution and diagnostic accuracy. As demand for a hybrid functional and anatomical imaging device has increased, integrated SPECT/CT systems have been used. In Korea, SPECT/CT was for the first time installed in 2003. SPECT/CT can eliminate many possible pitfalls on SPECT-alone images, making better attenuation correction and thereby improving image quality. Therefore, SPECT/CT is clinically preferred in many hospitals in various aspects. More recently, additional SPECT/CT images taken from the region with equivocal uptake on planar images have been helpful in making precise interpretation as part of their clinical workup in postoperative thyroid cancer patients. SPECT and SPECT/CT have various advantages, but its clinical application has gradually decreased in recent few years. While some researchers investigated the myocardial blood flow with cardiac PET using F-18 FDG or N-13 ammonia, myocardial perfusion SPECT is, at present, the radionuclide imaging study of choice for the risk stratification and guiding therapy in the coronary artery disease patients in Korea. New diagnostic radiopharmaceuticals for AD have received increasing attention; nevertheless, brain SPECT will remain the most reliable modality evaluating cerebral perfusion.

  15. Combined use of 64-slice computed tomography angiography and gated myocardial perfusion SPECT for the detection of functionally relevant coronary artery stenoses. First results in a clinical setting concerning patients with stable angina

    International Nuclear Information System (INIS)

    Hacker, M.; Hack, N.; Tiling, R.; Jakobs, T.; Nikolaou, K.; Becker, C.; Ziegler, F. von; Knez, A.; Koenig, A.; Klauss, V.

    2007-01-01

    Aim: In patients with stable angina pectoris both morphological and functional information about the coronary artery tree should be present before revascularization therapy is performed. High accuracy was shown for spiral computed tomography (MDCT) angiography acquired with a 64-slice CT scanner compared to invasive coronary angiography (ICA) in detecting obstructive'' coronary artery disease (CAD). Gated myocardial SPECT (MPI) is an established method for the noninvasive assessment of functional significance of coronary stenoses. Aim of the study was to evaluate the combination of 64-slice CT angiography plus MPI in comparison to ICA plus MPI in the detection of hemodynamically relevant coronary artery stenoses in a clinical setting. Patients, methods: 30 patients (63 ± 10.8 years, 23 men) with stable angina (21 with suspected, 9 with known CAD) were investigated. MPI, 64-slice CT angiography and ICA were performed, reversible and fixed perfusion defects were allocated to determining lesions separately for MDCT angiography and ICA. The combination of MDCT angiography plus MPI was compared to the results of ICA plus MPI. Results: Sensitivity, specificity, negative and positive predictive value for the combination of MDCT angiography plus MPI was 85%, 97%, 98% and 79%, respectively, on a vessel-based and 93%, 87%, 93% and 88%, respectively, on a patient-based level. 19 coronary arteries with stenoses =50% in both ICA and MDCT angiography showed no ischemia in MPI. Conclusion: The combination of 64-slice CT angiography and gated myocardial SPECT enabled a comprehensive non-invasive view of the anatomical and functional status of the coronary artery tree. (orig.)

  16. Combined use of 64-slice computed tomography angiography and gated myocardial perfusion SPECT for the detection of functionally relevant coronary artery stenoses. First results in a clinical setting concerning patients with stable angina

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, M.; Hack, N.; Tiling, R. [Klinikum Grosshadern (Germany). Dept. of Nuclear Medicine; Jakobs, T.; Nikolaou, K.; Becker, C. [Klinikum Grosshadern (Germany). Dept. of Clinical Radiology; Ziegler, F. von; Knez, A. [Klinikum Grosshadern (Germany). Dept. of Cardiology; Koenig, A.; Klauss, V. [Medizinische Poliklinik-Innenstadt, Univ. of Munich (Germany). Dept. of Cardiology

    2007-07-01

    Aim: In patients with stable angina pectoris both morphological and functional information about the coronary artery tree should be present before revascularization therapy is performed. High accuracy was shown for spiral computed tomography (MDCT) angiography acquired with a 64-slice CT scanner compared to invasive coronary angiography (ICA) in detecting ''obstructive'' coronary artery disease (CAD). Gated myocardial SPECT (MPI) is an established method for the noninvasive assessment of functional significance of coronary stenoses. Aim of the study was to evaluate the combination of 64-slice CT angiography plus MPI in comparison to ICA plus MPI in the detection of hemodynamically relevant coronary artery stenoses in a clinical setting. Patients, methods: 30 patients (63 {+-} 10.8 years, 23 men) with stable angina (21 with suspected, 9 with known CAD) were investigated. MPI, 64-slice CT angiography and ICA were performed, reversible and fixed perfusion defects were allocated to determining lesions separately for MDCT angiography and ICA. The combination of MDCT angiography plus MPI was compared to the results of ICA plus MPI. Results: Sensitivity, specificity, negative and positive predictive value for the combination of MDCT angiography plus MPI was 85%, 97%, 98% and 79%, respectively, on a vessel-based and 93%, 87%, 93% and 88%, respectively, on a patient-based level. 19 coronary arteries with stenoses =50% in both ICA and MDCT angiography showed no ischemia in MPI. Conclusion: The combination of 64-slice CT angiography and gated myocardial SPECT enabled a comprehensive non-invasive view of the anatomical and functional status of the coronary artery tree. (orig.)

  17. Experiencia de trabajo interdisciplinario en alfabetización básica con mujeres, promoción de su salud y derechos.

    Directory of Open Access Journals (Sweden)

    Sanabría Hernández, Marcela

    2015-01-01

    Full Text Available El artículo presenta una experiencia de trabajo interinstitucional e interdisciplinaria, entre la Caja Costarricense de Seguro Social- Área de Salud Goicoechea 2, Servicio de Trabajo Social con la Universidad Estatal a Distancia, Cátedra de Psicopedagogía, realizada en el Área de Salud Goicoechea 2, referente a la alfabetización básica con mujeres adultas, vecinas de los cantones de Moravia y Goicoechea, San José, Costa Rica. El proceso se llevó a cabo a partir de una metodología grupal socioeducativa para facilitar en las usuarias conocimientos básicos de alfabetización, útiles en sus actividades cotidianas, las cuales facilitarán su empoderamiento y atención integral de la salud. Se logró la implementación exitosa del proyecto, según los objetivos de aprendizaje propuestos, y se denotaron situaciones de desigualdad social que prevalecen en Costa Rica por categorías tales como el género y las condiciones socioeconómicas.Asimismo, se obtuvo la posibilidad de que a nivel interintitucional se vinculen proyectos para atender las necesidades de la población.

  18. Evaluation of left ventricular function and volume with multidetector-row computed tomography. Comparison with electrocardiogram-gated single photon emission computed tomography

    International Nuclear Information System (INIS)

    Suzuki, Takeya; Yamashina, Shohei; Nanjou, Shuji; Yamazaki, Junichi

    2007-01-01

    This study compared left ventricular systolic function and volume determined by multidetector-row computed tomography (MDCT) and electrocardiogram-gated single photon emission computed tomography (G-SPECT) Thirty-seven patients with coronary artery disease and non-cardiovascular disease underwent MDCT. In this study, left ventricular ejection fraction (EF), left ventricular end-diastolic volume (EDV) and left ventricular end-systolic volume (ESV) were calculated using only two-phase imaging with MDCT. Left ventricular function and volume were compared using measurements from G-SPECT. We conducted MDCT and G-SPECT virtually simultaneously. Both the EF and ESV evaluated by MDCT closely correlated with G-SPECT (r=0.763, P 65 bpm) during MDCT significantly influenced the difference in EF calculated from MDCT and G-SPECT (P<0.05). Left ventricular function can be measured with MDCT as well as G-SPECT. However, a heart rate over 65 bpm during MDCT negatively affects the EF correlation between MDCT and G-SPECT. (author)

  19. Implementation and application of simulation platform of PET based on GATE

    International Nuclear Information System (INIS)

    Zhang Bin; Zhao Shujun; Zhang Shixun; Liu Haojia

    2010-01-01

    Positron emission tomography (PET) is a tool for obtaining functional image in vivo and GATE is a dedicated software for PET/SPECT simulation based on Mentor Carlo Method. It encapsulates the Geant4 libraries to achieve a modular and provides a number of new characteristics. In practice, a simulation platform of PET has been builded employing GATE based on Ubuntu operating system, including many keys and skills in the process. We have exploited benchmark PET, a testing example in GATE, and implemented PET scanner simulation in the end. Through analyzing the simulation data, the result demonstrate that predictive goal has been reached. The work provides the foundation for investigating PET scanner and optimizing the algorithm of tomograph image reconstruction. (authors)

  20. La experiencia semestral

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    Heidi Cañón

    2003-11-01

    Full Text Available La Corporación Opción Colombia brinda a los estudiantes universitarios la posibilidad de confrontar la teoría de las aulas con la realidad del país. Quienes aplican al programa reciben talleres de capacitación e información sobre los convenios vigentes y los perfiles requeridos par cada uno de ellos. Superada esta primera etapa y de acuerdo con sus expectativas, el estudiante aplica a algunos de los proyectos y la corporación se encarga de ubicarlo en alguna zona del país. En este artículo, el lector conocerá el caso de una estudiante de la Facultad de Administración de Empresas Turísticas y Hoteleras, quien fue ubicada en los municipios Pijao y La Tebaida (Quindío para desarrollar actividades dentro del programa Computadores para Educar, iniciativa que busca proveer de tecnología a las escuelas públicas. La autora deja entrever sus emociones, su visión antes y después de esta experiencia y los aportes dados y recibidos durante el proceso.

  1. Prognostic implications of post-stress ejection fraction decrease detected by gated SPECT in the absence of stress-induced perfusion abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    Dona, Manjola; Massi, Lucia; Settimo, Leonardo; Bartolini, Matteo; Gianni, Gianluca; Pupi, Alberto; Sciagra, Roberto [University of Florence, Nuclear Medicine Unit, Department of Clinical Physiopathology, Florence (Italy)

    2011-03-15

    The prognostic meaning of a post-stress ejection fraction (EF) decrease detected by perfusion gated SPECT is still unclear. We therefore followed up patients with post-stress EF decrease in the absence of stress-induced perfusion abnormalities. We prospectively enrolled 57 consecutive patients with post-stress EF drop {>=} 5 EF units and summed difference score (SDS) {<=} 1. They were followed up for more than 1 year and their outcome was compared with a group of sex- and age-matched controls with the same SDS but without EF decrease. During follow-up there were 13 events (1 cardiac death, 1 non-fatal myocardial infarction, 1 congestive heart failure and 10 late revascularizations). In the control group we registered six events. There was a significant difference (p < 0.0001) between the event-free survival curves of the two groups. The event rate of patients with post-stress EF decrease {>=} 5 EF units is relatively high and is significantly worse than that of a control group of patients with similarly normal SDS but without EF changes. Therefore, a post-stress EF decrease without stress-induced perfusion abnormalities should be cautiously interpreted. (orig.)

  2. Effect of bypass on the motor activation SPECT compared to the acetazolamide SPECT

    International Nuclear Information System (INIS)

    Kawaguchi, Shoichiro; Iwahashi, Hideaki; Sakaki, Toshisuke; Imai, Teruhiko; Ohishi, Hajime

    2002-01-01

    The authors evaluated and analyzed motor activation single photon emission computed tomography (M-SPECT) in ischemic cerebrovascular disease compared to resting and acetazolamide (ACZ) activated SPECT studies. Seventeen cases with STA-MCA bypass performed for ischemic cerebrovascular disease were examined. The SPECT studies consisting of resting, ACZ activation, and motor activation stages were performed before bypass, at 1 month, and 3 months after bypass. The result of the M-SPECT was expressed as negative or positive. Before bypass: In all 17 cases, SPECT studies of the affected side showed reduction of resting cerebral blood flow (CBF) and reduction of cerebrovascular reserve capacity (CVRC). Eight cases were positive in the M-SPECT study. One week after bypass: The resting CBF increased in seven cases. Four showed preoperative positive M-SPECT. Eight cases showed improvement of the CVRC. Twelve cases were positive in M-SPECT, and two were negative in the preoperative M-SPECT. Three months after bypass: Thirteen cases showed improvement in the resting CBF, and fourteen cases showed improvement of the CVRC. Fourteen cases were positive in the M-SPECT, and among these, 6 were negative in the preoperative M-SPECT. There was a discrepancy between the improvement in CVRC and M-SPECT. M-SPECT study can provide information about the degree of hemodynamic compromise and effect of bypass surgery. (author)

  3. Effect of bypass on the motor activation SPECT compared to the acetazolamide SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Kawaguchi, Shoichiro; Iwahashi, Hideaki; Sakaki, Toshisuke; Imai, Teruhiko; Ohishi, Hajime [Nara Medical Univ., Kashihara (Japan)

    2002-03-01

    The authors evaluated and analyzed motor activation single photon emission computed tomography (M-SPECT) in ischemic cerebrovascular disease compared to resting and acetazolamide (ACZ) activated SPECT studies. Seventeen cases with STA-MCA bypass performed for ischemic cerebrovascular disease were examined. The SPECT studies consisting of resting, ACZ activation, and motor activation stages were performed before bypass, at 1 month, and 3 months after bypass. The result of the M-SPECT was expressed as negative or positive. Before bypass: In all 17 cases, SPECT studies of the affected side showed reduction of resting cerebral blood flow (CBF) and reduction of cerebrovascular reserve capacity (CVRC). Eight cases were positive in the M-SPECT study. One week after bypass: The resting CBF increased in seven cases. Four showed preoperative positive M-SPECT. Eight cases showed improvement of the CVRC. Twelve cases were positive in M-SPECT, and two were negative in the preoperative M-SPECT. Three months after bypass: Thirteen cases showed improvement in the resting CBF, and fourteen cases showed improvement of the CVRC. Fourteen cases were positive in the M-SPECT, and among these, 6 were negative in the preoperative M-SPECT. There was a discrepancy between the improvement in CVRC and M-SPECT. M-SPECT study can provide information about the degree of hemodynamic compromise and effect of bypass surgery. (author)

  4. Experiencia en el manejo del paciente con VIH entre médicos de la Secretaría de Salud Experience in HIV patient care among physicians of the National Health Ministry

    Directory of Open Access Journals (Sweden)

    Carlos Magis-Rodríguez

    1999-12-01

    Full Text Available OBJETIVO: Conocer la experiencia que los médicos de la Secretaría de Salud (SSA han obtenido en el manejo del sujeto infectado por el VIH y en el uso de antirretrovirales. MATERIAL Y MÉTODOS: Se realizó un estudio transversal, con el apoyo del Consejo Nacional para la Prevención y el Control del SIDA (CONASIDA, en marzo-mayo de 1998. Se proporcionaron cuestionarios autoaplicables a médicos de la SSA con experiencia en el manejo clínico del paciente con VIH, al inicio de cinco simposios sobre VIH/SIDA, realizados en diversas ciudades del país. El análisis estadístico incluyó la prueba ji². RESULTADOS: Se recolectaron 181 encuestas. La mediana de pacientes con VIH atendidos fue de cuatro (intervalo 1-97. De los médicos encuestados, 36.5% manifestó administrar antirretrovirales (35.4% prescribía los análogos de los nucleósidos, y 9.9%, los inhibidores de proteasa. Los fármacos más usados fueron AZT y ddI (40.3%. Expresó 17.7% de los médicos haber utilizado la cuenta de linfocitos T CD4+, y 8.8% la carga viral como indicadores pronósticos y de respuesta a la farmacoterapia. CONCLUSIONES: Se observó una baja proporción de médicos de la SSA con experiencia en el manejo del paciente con VIH y en el uso de los antirretrovirales. Se deben enfocar esfuerzos para mejorar la atención de los pacientes VIH positivos mediante la capacitación del personal médico.OBJETIVE: To determine the experience of the National Health Ministry Physicians in the management of HIV infecetd patients and in the use of antiretrovirals. MATERIAL AND METHOD: A descriptive, observational and transversal study was performed, with support from the National AIDS Council from March to May 1998. Self-applicable questionnaires were filled by National Health Ministry physicians with experience in HIV patient clinical care, at the beginning of 5 different meetings on HIV/AIDS in several cities of the country. Statistical analysis included the chi² test. RESULTS

  5. EXPERIENCIA INTEGRADORA PARA EDUCACIÓN AMBIENTAL

    Directory of Open Access Journals (Sweden)

    Jorge F. Coronel

    2015-01-01

    Full Text Available En este trabajo se relacionó la práctica experimental de laboratorio co n el análisis de problemas ambientales. El objetivo de este trabajo es analizar una propuesta que vinculó el trabajo experimental con la situación del ambiente local para promover el cuidado de la naturaleza y su uso con sostenibilidad . Esta estrategia brindó un enfoque integrador aportando a los alumnos de profesorado una alternativa de aprendizaje con exper iencias sencillas para el estudio cualitativo de l ambiente local y motivar a l análisis de problemas asociad o s. Las experiencias permitieron caracterizar las muestras de suelo, agua y aire del lugar de residencia de los alumnos. La información experimental obtenida potenció la discusión de la situación ambiental actual. E l enfoque de enseñanza basado en problemas socio - científicos posibilit ó la visión interdisciplinar del tema , redimensionando valores y acciones para el cuidado ambiental y el desarrollo sustentable.

  6. Renal SPECT with {sup 99m} Tc-Dmsa. Reorientation and processing; SPECT renal con {sup 99m} Tc-Dmsa. Reorientacion y procesamiento

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, J.L.; Perera, A.; Fraxedas, R. [Centro de InvestigacionesClinicas 34 no.4501 e/45 y 47 Kohly, Playa C. Habana (Cuba)

    1998-12-31

    For the study of different renal affections with repercussion in the parenchyma is widely used the plane gammagraphy wit {sup 99m} Tc-Dmsa though not in the same way the SPECT technique. In general, the different inclination and orientation of the longitudinal axes of both kidneys in the patients entail aid to high variability in the detection of the different types of defects which leads to a possible mistaken diagnostic. With a view to this,it was developed in our centre a methodology for the automated reorientation of the different renal volumes obtained by SPECT and its posterior processing, obtaining as result a software with a high grade of independence from the operator. In this way, it is obtained a procedure standardization and so it let us with major rigor to realize evolutive studies of the patients. (Author)

  7. Experiencia inicial en la cirugía cardiovascular con circulación extracorpórea en recién nacidos prematuros con un peso menor de 2.500 gramos

    Directory of Open Access Journals (Sweden)

    Christian Kreutzer

    2010-01-01

    Full Text Available RESUMENIntroducciónNo obstante el progreso sostenido en cirugía cardiovascular neonatal en los últimos 30 años,los recién nacidos prematuros con cardiopatías congénitas presentan un desafío adicional alequipo multidisciplinario interviniente debido a la frecuente asociación de comorbilidades ybajo peso. A diferencia de las estrategias históricas diferidas de diferir la cirugía, desde 2007llevamos a cabo cirugías correctoras sin importar el peso ni la edad en pacientes sintomáticoscon el propósito de mejorar su estado cardíaco para que pudieran superar las comorbilidadesasociadas.ObjetivoComunicar la experiencia inicial en cirugía cardiovascular (CCV con circulación extracorpórea(CEC en neonatos de menos de 2.500 gramos.Material y métodosDe mayo de 2007 a mayo de 2009, 11 neonatos fueron intervenidos con CEC. La edad mediafue de 24 días (4 a 90 días, la edad gestacional media fue de 34 semanas (32 a 37 y el pesomedio, de 2,27 kg (1,7 a 2,5. Previo a la intervención, siete pacientes estaban con asistenciarespiratoria mecánica (ARM y nueve con inotrópicos. Los diagnósticos fueron comunicacióninterventricular (n = 4, uno con coartación de la aorta grave, anomalía total del retornovenoso pulmonar (n = 2, transposición de grandes arterias (n = 2, atresia pulmonarcon septum íntegro (n = 1, atresia pulmonar con comunicación interventricular (n = 1 ehipoplasia del ventrículo izquierdo (n = 1. Se utilizó hipotermia profunda a 18 °C de temperaturarectal con paro circulatorio total intermitente (n = 8 o flujo completo a 28 °C detemperatura rectal (n = 3. En 10 pacientes se realizó cirugía correctora biventricular y enuno se efectuó cirugía de Norwood.ResultadosEn 8 pacientes se dejó el esternón abierto, con un tiempo medio al cierre de 3,5 días (3 a 5.Tres pacientes requirieron factor VII por presentar sangrado incoercible. El tiempo mediode ARM fue de 7,5 días (2 a 20. Las complicaciones más comunes fueron

  8. Examen de post-efecto para experiencias anómalo/ paranormales con un abordaje humanista

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    Alejandro Parra

    2014-07-01

    Full Text Available Se presentan los resultados de una investigación que tuvo como objetivos: explorar la utilidad de la terapia grupal para hacer frente a los efectos de las experiencias paranormales y explorar cómo la terapia humanista produce cambios positivos hacia las experiencias anómalo/paranormales. Se les pidió a la muestra (N= 20, rango 22-71 años, M= 45,65, DT= 12,52, 65 % mujeres y 35 % varones, responder un cuestionario autoadministrado de siete preguntas antes y al finalizar su participación en un grupo. La actividad incluyó tres fases: (1 Exposición, (2 Interpretación y (3 Cierre del grupo. Los participantes indicaron que el grupo ayudó a disminuir su malestar emocional (p = ,001, y lograr una comprensión a sus experiencias (p = ,008. Abstract This article shows the results of an investigation aimed to: explore the usefulness of group therapy to deal with the effects of paranormal experiences and explore how humanistic therapy produces positive changes to the anomalous/paranormal experiences. They were asked to sample (N = 20, range 22-71 years, M = 45.65, SD = 12.52, 65 % female and 35 % male, a self-administered questionnaire to answer seven questions before and after your participation in a group. The activity included three phases: (1 Exposure (2 Interpretation y (3 Close the group. Participants indicated that the group helped reduce their emotional distress (p = .001, and gain an understanding of their experiences (p = .008.

  9. Quantitative gated SPECT: the effect of reconstruction filter on calculated left ventricular ejection fractions and volumes

    International Nuclear Information System (INIS)

    Wright, Graham A.; McDade, Mark; Martin, William; Hutton, William

    2002-01-01

    Gated SPECT (GSPECT) offers the possibility of obtaining additional functional information from perfusion studies, including calculation of left ventricular ejection fraction (LVEF). The calculation of LVEF relies upon the identification of the endocardial surface, which will be affected by the spatial resolution and statistical noise in the reconstructed images. The aim of this study was to compare LVEFs and ventricular volumes calculated from GSPECT using six reconstruction filters. GSPECT and radionuclide ventriculography (RNVG) were performed on 40 patients; filtered back projection was used to reconstruct the datasets with each filter. LVEFs and volumes were calculated using the Cedars-Sinai QGS package. The correlation coefficient between RNVG and GSPECT ranged from 0.81 to 0.86 with higher correlations for smoother filters. The narrowest prediction interval was 11±2%. There was a trend towards higher LVEF values with smoother filters, the ramp filter yielding LVEFs 2.55±3.10% (p<0.001) lower than the Hann filter. There was an overall fall in ventricular volumes with smoother filters with a mean difference of 13.98±10.15 ml (p<0.001) in EDV between the Butterworth-0.5 and Butterworth-0.3 filters. In conclusion, smoother reconstruction filters lead to lower volumes and higher ejection fractions with the QGS algorithm, with the Butterworth-0.4 filter giving the highest correlation with LVEFs from RNVG. Even if the optimal filter is chosen the uncertainty in the measured ejection fractions is still too great to be clinically acceptable. (author)

  10. Diálogo con Manuel Chiriboga sobre nueva ruralidad

    OpenAIRE

    Pérez E, Laura

    2012-01-01

    Introducción Lo que sigue es una conversación por correo electrónico que Laura Pérez E., de PERSPECTIVAS RURALES, mantuvo con Manuel Chiriboga, especialista en desarrollo rural, con amplia experiencia en toda América Latina y la problemática de su país, Ecuador…

  11. Analysis of the diagnostic value of the Gated-SPECT study of myocardial perfusion in the diagnosis of coronary disease in users seen at the Hospital Rafael Angel Calderon Guardia

    International Nuclear Information System (INIS)

    Calvo Montero, Karla; Coto Rodriguez, Maria Fernanda

    2011-01-01

    An analysis of the diagnostic value of the Gated-SPECT study of myocardial perfusion with Sestamibi marked with 99m Tc for the diagnosis of Coronary Disease was performed at the Hospital Rafael Angel Calderon Guardia. 13 patients with nuclear study and coronary angiography performed, were selected for the investigation. An estimate of the sensitivity, specificity and predictive values of the myocardial perfusion study was performed for the detection of the disease. Then, these values were related to socio-demographic and clinical characteristics of the patients submitted to the diagnosis. The need to use appropriate criteria to request this type of study was evidenced when determining that most of the patients presented risk factors compared to 26% of patients who did not present any factor [es

  12. Profesores-artistas y didáctica generativa: Experiencias educativas en la universidad.

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    Alejandra Montané-López

    2009-01-01

    Full Text Available El presente artículo es fruto del estudio de tesis doctoral que versa sobre las experiencias pedagógicas innovadoras del profesorado universitario vinculado con el Arte –específicamente con las artes escénicas- y que desarrolla su actividad profesional en los estudios de educación (Pedagogía, Educación Social y Magisterio. La estructura del mismo está compuesta por una introducción, un marco teórico-contextual, la metodología y unas conclusiones y propuestas. El análisis de los saberes didácticos nacidos de la génesis entre el saber pedagógico y el saber artístico configuran conceptualmente una didáctica generativa en el contexto universitario. Se delimitan las competencias complejas del profesorado universitario vinculado al Arte -a través del análisis de las experiencias pedagógicas en educación superior- partiendo inicialmente del modelo del “artista pedagogo” (Barret, 1995; Laferrièrre,2000 sumergiéndose en las configuraciones didácticas alternativas e innovadoras que actualmente encuentran su adecuación con la declaración del 2009 como el Año Internacional de la Creatividad y la Innovación.

  13. Manual o digital. Arquitectura, experiencia del cuerpo y código digital

    OpenAIRE

    Trachana, Angelique

    2012-01-01

    Esta aportación trata la incompatibilidad del dibujo por ordenador con la configuración del espacio vivencial trazado con la mano como extensión del cuerpo. Aportamos una experiencia docente del dibujar para proyectar en arquitectura. El código digital, como sabemos, es un lenguaje abstracto, originado en la matemática cuyos signos y operaciones no describen cualidades del sujeto. La utilización del software para proyectar implica que el arquitecto depende de un suministrador que le proporcio...

  14. Experiencias de vida económica y desarrollo humano de estudiantes universitarios de otras localidades en Barranquilla (Colombia

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    Mayilin Moreno Torres

    2004-01-01

    Full Text Available Esta investigación se propuso indagar si las experiencias económicas vividas en Barranquilla (Colombia por estudiantes universitarios provenientes de otras localidades favorecían su desarrollo humano. Para llevarla a cabo se utilizó un método cualitativo con orientación interpretativa. Los resultados mostraron que las experiencias económicas sí contribuyen notablemente a la construcción de desarrollo humano porque logran tener mucho significado en la vida de estos estudiantes. Es decir, a medida que viven estas experiencias, las decisiones de su vida van teniendo un solo y auténtico sujeto: él mismo. En consecuencia, lo que se impone es su libertad, su autonomía. Estas experiencias económicas, por tanto, no sólo le permiten tomar distancia de sus propios impulsos sino también de la tradición. Ello configura una experiencia de progreso, de ilustración, de modernidad.

  15. Dolor crónico, corporalidad y clausura: percepciones y   experiencias sobre la migraña

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    Romina del Monaco

    2012-05-01

    Full Text Available Este artículo analiza, desde una perspectiva socio‐antropológica, las percepciones y experiencias de personas con un tipo de dolor de cabeza crónico, que los profesionales de la salud y los pa‐ cientes denominan migraña. El trabajo de campo se llevó a cabo en un hospital público de la Ciudad de Buenos Aires, donde se realizaron entrevistas a médicos neurólogos y personas con esta dolencia. Combinando la perspectiva fenomenológica con el interaccionismo simbólico propongo indagar cómo la percepción y las experiencias con el dolor influyen en la constitución de sí mismo, de la corporalidad y de las interacciones con los otros.   Asimismo, se observan algunas particularidades de la migraña que la diferencian de otras dolen‐ cias crónicas y que condicionan los modos en que los pacientes se relacionan con su entorno. En primer lugar, carece de condiciones fácticas de verificación y no tiene una etiología precisa ni un tratamiento eficaz. En segundo lugar, las personas entrevistadas decían que se tiende a vincular esta dolencia con excusas, mentiras y manipulación. A partir de esto surgen cuestiones que vin‐ culan el padecimiento con falta de legitimidad, angustia, aperturas y clausuras del yo que influ‐ yen en las relaciones consigo mismos y con los otros. 

  16. Aproximación a una categorización de los sistemas de productos: el uso y la experiencia del consumidor como configuradores

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    John Jairo Cardozo Vásquez

    2015-10-01

    Full Text Available Con la transformación en las formas de relación con los productos, los consumidores han dejado de ser receptores pasivos de funciones para transformarse en co-creadores de los productos, así como buscadores de experiencias y sensaciones. Múltiples estudios demuestran cómo los ecosistemas de productos son el ambiente en el que se realizan estas interacciones entre consumidores y productos (Jiao, Xu, Du, Zhang, Helander, Khalid y Ni, 2007; Zhou, Xu y Jiao, 2011, donde las experiencias y sensaciones del usuario son optimizadas a través de la estrategia de categorización, lo que permite establecer agrupaciones de productos basadas en la similitud percibida. Este estudio busca establecer la manera como el uso y la experiencia influyen en el diseño de los productos de una categoría. Se proponen 8 agrupaciones que describen las formas de interacción de los consumidores con los productos, las cuales son estudiadas mediante el modelo de sistemas de productos. Para evaluar estos planteamientos se aplica una encuesta a 57 expertos en el área del diseño, enfocada en determinar el grado de afectación de la experiencia y el uso en la caracterización de los sistemas de productos. A partir del análisis de los datos, se extrae una escala del grado de énfasis requerido en cada variable. Los resultados son contrastados con la literatura y se discuten sus implicaciones para el diseño de categorías mediante el modelado de sistemas de productos.

  17. El conocimiento profesional adquirido por el entrenador de balonmano: experiencias y formación

    Directory of Open Access Journals (Sweden)

    Sebasti\\u00E1n Feu Molina

    2012-01-01

    Full Text Available El objetivo del estudio fue conocer la procedencia del conocimiento que utilizan los entrenadores de balonmano en su ejercicio profesional. En el estudio participaron 333 entrenadores españoles, 86.8% hombres y 13.2% mujeres. Se diseñó y validó un cuestionario que permitió conocer la influencia del conocimiento profesional en su intervención como entrenador: experiencia como jugador, formación académica o experiencia como entrenador. El análisis estadístico reflejó que los factores de la escala tenían una validez y fiabilidad adecuadas (¿ > .70, acreditando a este cuestionario como una herramienta válida y fiable. Los entrenadores utilizan las tres fuentes de conocimiento (académica, experiencia como jugador y autoformación, existiendo una mayor utilización del conocimiento académico. Los entrenadores con mayor formación utilizan menos las experiencias y conocimientos adquiridos como jugador y utilizan más los conocimientos adquiridos en su vida profesional.

  18. La narrativa transmedia como experiencia de simulación de inteligencia colectiva. El caso de Atrapados

    Directory of Open Access Journals (Sweden)

    Jaime Alejandro Rodríguez Ruiz

    2015-01-01

    Full Text Available Este artículo describe y analiza la experiencia transmedia del proyecto de investigación “Simulador IC, un escenario transmedial de pruebas para la simulación de inteligencia colectiva”, en el que se exploró la capacidad de cuatro artefactos ficcionales — texto literario, cómic, videojuego y juego de rol—, generados a partir de la transmediación de un texto literario fuente, para desarrollar sensibilidad en la resolución de problemas con características vinculadas a la inteligencia colectiva. El método de investigación fue mixto, con un componente principal cualitativo y un componente cuantitativo —metodología observacional—. Al realizarse una medición del gradiente de inteligencia colectiva de los participantes, tras el contacto y la interacción con diversas estrategias de simulación de los problemas —combinación de artefactos, según un diseño experimental específico—, se comprobó que la experiencia transmedia completa, es decir, la interac - ción con los cuatro artefactos potencia los efectos y beneficios de la simulación con artefactos individuales. Se concluye también que los participantes que interactuaron con diversas combinaciones de artefactos ofrecieron alternativas de solución colaborativas a problemas de la vida cotidiana.

  19. Property of electrocardiogram gated single photon emission tomography by 99mTc-methoxy isobutyl isonitrile

    International Nuclear Information System (INIS)

    Imai, Kamon; Nishio, Yukari; Araki, Yasushi; Saito, Satoshi; Ozawa, Yukio; Yasugi, Tadao; Hagiwara, Kazuo; Kamata, Rikisaburo

    1992-01-01

    99m Tc-methoxy isobutyl isonitrile (MIBI) is a new developed myocardial perfusion imaging agent. Because this compound has higher photon energy than thallium (Tl), electrocardiogram gated single photon emission tomography (SPECT): end-diastolic (ED) and end-systolic (ES) short axis (SA) images could be taken. To investigate property of gated MIBI SPECT, MIBI myocardial scintigraphy, Tl scintigraphy (TMS) and analysis of left ventricular wall motion were performed in 6 patients with myocardial infarction. Left ventricule was divided into 8 segments. Perfusion defect (PD) was scored: '0' (normal), '1' (hypo-perfusion), '2' (defect). Wall motion abnormality (WMA) was also scored: '0' (normo-kinesis), '1' (hypo-kinesis), '2' (a-, dys-kinesis). Severity and extent of PD and WMA were calculated. Severity of WMA was 3.0±2.0 (M±SD), severity of PD was 3.3±1.7 in TMS, 3.7±1.3 in no-gated MIBI, 5.0±0.6 in ES-MIBI, 7.3±2.0 in ED-MIBI. Extent of WMA was 2.3±1.0. Extent of PD was 2.5±1.3 in TMS, 3.0±1.6 in no-gated MIBI, 3.5±0.8 in ES-MIBI, 4.8±1.0 in ED-MIBI. Compared with wall motion abnormality, severity and extent of PD in ED-MIBI was larger. From our data, it is concluded that perfusion defect in ED-MIBI was overestimated significantly. When we evaluate gated MIBI image, we must consider this property. (author)

  20. Electrocardiograph-gated single photon emission computed tomography radionuclide angiography presents good interstudy reproducibility for the quantification of global systolic right ventricular function.

    Science.gov (United States)

    Daou, Doumit; Coaguila, Carlos; Vilain, Didier

    2007-05-01

    Electrocardiograph-gated single photon emission computed tomography (SPECT) radionuclide angiography provides accurate measurement of right ventricular ejection fraction and end-diastolic and end-systolic volumes. In this study, we report the interstudy precision and reliability of SPECT radionuclide angiography for the measurement of global systolic right ventricular function using two, three-dimensional volume processing methods (SPECT-QBS, SPECT-35%). These were compared with equilibrium planar radionuclide angiography. Ten patients with chronic coronary artery disease having two SPECT and planar radionuclide angiography acquisitions were included. For the right ventricular ejection fraction, end-diastolic volume and end-systolic volume, the interstudy precision and reliability were better with SPECT-35% than with SPECT-QBS. The sample sizes needed to objectify a change in right ventricular volumes or ejection fraction were lower with SPECT-35% than with SPECT-QBS. The interstudy precision and reliability of SPECT-35% and SPECT-QBS for the right ventricle were better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography on the same population. SPECT-35% and SPECT-QBS present good interstudy precision and reliability for right ventricular function, with the results favouring the use of SPECT-35%. The results are better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography. They need to be confirmed in a larger population.

  1. Experiencias y vivencias en la Ingeniería Clínica

    OpenAIRE

    Saldarriaga, O. D. (Óscar Darío)

    2008-01-01

    Comparto con ustedes las experiencias y vivencias en el desarrollo y evolución en la ingeniería en los hospitales y clínicas, en especial la Ingeniería Clínica (IC). Antes, una breve explicación del desarrollo del Departamento de Ingeniería y Mantenimiento en el Hospital Pablo Tobón Uribe (El Hospital).

  2. Tiempo de Respuestas y Experiencia de Usuario Estudio Experimental

    Directory of Open Access Journals (Sweden)

    Delvis Echeverria

    2016-12-01

    Full Text Available La investigación está fundamentada por un estudio experimental, enfocado en la evaluación del comportamiento de los usuarios finales interactuando con tiempos de respuestas en aplicaciones reales. Se tomará como base el aporte de los autores Doherty y Thadani, investigadores de IBM relacionado con los tiempos de respuestas, y las investigaciones de Jacob Nielsen. Se llevarán a cabo un test con usuarios finales, y se expondrán optimizaciones a través de del uso de herramientas que contribuirán a mejorar los tiempos de respuestas de las aplicaciones web. Todo esto engloba una primera instancia de un proyecto que se está llevando a cabo en la empresa GeneXus Consulting, pretendiéndose lograr un punto de encuentro entre el rendimiento de las aplicaciones y la experiencia de usuario.

  3. Molecular imaging agents for SPECT (and SPECT/CT)

    International Nuclear Information System (INIS)

    Gnanasegaran, Gopinath; Ballinger, James R.

    2014-01-01

    The development of hybrid single photon emission computed tomography/computed tomography (SPECT/CT) cameras has increased the diagnostic value of many existing single photon radiopharmaceuticals. Precise anatomical localization of lesions greatly increases diagnostic confidence in bone imaging of the extremities, infection imaging, sentinel lymph node localization, and imaging in other areas. Accurate anatomical localization is particularly important prior to surgery, especially involving the parathyroid glands and sentinel lymph node procedures. SPECT/CT plays a role in characterization of lesions, particularly in bone scintigraphy and radioiodine imaging of metastatic thyroid cancer. In the development of novel tracers, SPECT/CT is particularly important in monitoring response to therapies that do not result in an early change in lesion size. Preclinical SPECT/CT devices, which actually have spatial resolution superior to PET/CT devices, have become essential in characterization of the biodistribution and tissue kinetics of novel tracers, allowing coregistration of serial studies within the same animals, which serves both to reduce biological variability and reduce the number of animals required. In conclusion, SPECT/CT increases the utility of existing radiopharmaceuticals and plays a pivotal role in the evaluation of novel tracers. (orig.)

  4. Molecular imaging agents for SPECT (and SPECT/CT)

    Energy Technology Data Exchange (ETDEWEB)

    Gnanasegaran, Gopinath [Guy' s and St Thomas' NHS Foundation Trust, Department of Nuclear Medicine, London (United Kingdom); Ballinger, James R. [Guy' s and St Thomas' NHS Foundation Trust, Department of Nuclear Medicine, London (United Kingdom); King' s College London, Division of Imaging Sciences and Biomedical Engineering, London (United Kingdom)

    2014-05-15

    The development of hybrid single photon emission computed tomography/computed tomography (SPECT/CT) cameras has increased the diagnostic value of many existing single photon radiopharmaceuticals. Precise anatomical localization of lesions greatly increases diagnostic confidence in bone imaging of the extremities, infection imaging, sentinel lymph node localization, and imaging in other areas. Accurate anatomical localization is particularly important prior to surgery, especially involving the parathyroid glands and sentinel lymph node procedures. SPECT/CT plays a role in characterization of lesions, particularly in bone scintigraphy and radioiodine imaging of metastatic thyroid cancer. In the development of novel tracers, SPECT/CT is particularly important in monitoring response to therapies that do not result in an early change in lesion size. Preclinical SPECT/CT devices, which actually have spatial resolution superior to PET/CT devices, have become essential in characterization of the biodistribution and tissue kinetics of novel tracers, allowing coregistration of serial studies within the same animals, which serves both to reduce biological variability and reduce the number of animals required. In conclusion, SPECT/CT increases the utility of existing radiopharmaceuticals and plays a pivotal role in the evaluation of novel tracers. (orig.)

  5. SPECT in psychiatry. SPECT in der Psychiatrie

    Energy Technology Data Exchange (ETDEWEB)

    Barocka, A. (Psychiatrische Klinik und Poliklinik, Erlangen (Germany)); Feistel, H. (Nuklearmedizinische Klinik, Erlangen (Germany)); Ebert, D. (Psychiatrische Klinik und Poliklinik, Erlangen (Germany)); Lungershausen, E. (Psychiatrische Klinik und Poliklinik, Erlangen (Germany))

    1993-08-13

    This review presents Single Photon Emission Computed Tomography (SPECT) as a powerful tool for clinical use and research in psychiatry. Its focus is on regional cerebral blood flow, measured with technetium labelled HMPAO. In addition, first results with brain receptor imaging, concerning dopamin-D[sub 2] and benzodiazepine receptors, are covered. Due to major improvements in image quality, and impressive number of results has been accumulated in the past three years. The authors caution against using SPECT results as markers for disease entities. A finding like 'hypofrontality' is considered typical of a variety of mental disorders. Clearly both, more experience with SPECT and contributions from psychopathology, are needed. (orig.)

  6. Enseñando comunicación con mapas conceptuales: experiencias y posibilidades

    Directory of Open Access Journals (Sweden)

    Carlos Araya Rivera

    2012-01-01

    Full Text Available Este ensayo reseña algunas experiencias en el uso de mapas conceptuales para la enseñanza de las Ciencias de la Comunicación, desarrolladas por el autor en tres cursos impartidos en la Universidad de Costa Rica entre el 2007 y el 2010. Se reflexiona en cuanto a la aplicación de esta herramienta y sus posibilidades didácticas, y se ofrece algunas recomendaciones para aprovechar mejor el potencial de los mapas conceptuales.

  7. Detection of myocardial stunning with gated SPECT and its relationship with location, extension and severity of perfusion defects induced by exercise or pharmacologic stress

    International Nuclear Information System (INIS)

    Mut, F.; Beretta, M.; Vidal, I.; Rener, A.; Alonso, O.

    2002-01-01

    Aim: To investigate the relationship between transient ventricular dysfunction detected by gated SPECT with the location, extension and severity of ischemic areas in patients with reversible perfusion defects. Material and Methods: We retrospectively studied 83 patients (61±11 yrs., 61 men, 27 with previous MI) submitted for coronary artery disease (CAD) evaluation with 99mTc-MIBI gated SPECT using a 2-day protocol whose perfusion imaging pattern had been reported positive for myocardial ischemia. Stress test was exercise in 54 cases, dipyridamole in 28 and dobutamine in 1. Previous work from our group demonstrated up to 12% change in LVEF from rest to post-stress in a population with low likelihood of CAD and a normal perfusion pattern. Thus, according to % variation of left ventricular ejection fraction (LVEF) from rest to post-stress we further divided the population into 2 subgroups, (A) with less than 12% change in LVEF (n=56) and (B) with more than 12% negative variation (n=27). For evaluation of perfusion, a simplified 7-segment division of the myocardium was used and a combined ischemic score was obtained by multiplying the number of segments with reversible defects by the 1-4 assigned severity score. Results: There was no significant difference between the two groups regarding age, gender, stress result (clinical or ECG), number of fixed perfusion defects or rest LVEF. Dipyridamole test was more frequent among patients of group B. Post-stress LVEF was 49±14% for group A and 41±15% for group B, p=0.0125. Combined ischemic score was 6.82±6.5 vs. 11.96±12 respectively, p=0.014. In patients of group A, defects corresponding to the right coronary territory were more frequent, while the left descending artery territory was more commonly affected in group B patients, however this was not statistically significant. Left circumflex territory was equally affected in both groups. Conclusion: Transient ventricular dysfunction after a stress test can be

  8. Experiencia del examen estatal en la carrera de estomatología

    OpenAIRE

    Chiu Navarro, Violeta; Rodríguez Méndez, Gladys; Alonso Pardo, María E.

    1997-01-01

    Se exponen los resultados alcanzados en la primera experiencia realizada con la aplicación del examen estatal en la carrera de Estomatología, en el curso académico 1995-1996, con el nuevo plan de estudios (plan C) para formar estomatólogos generales básicos. En los objetivos, propósitos y directrices de la salud pública cubana, orientados a elevar los niveles de salud de la población, se exigen una serie de decisiones y medidas entre las que se destacan por su importancia, la formación de pro...

  9. Mindfulness en la Educación: experiencias y perspectivas desde Brasil

    Directory of Open Access Journals (Sweden)

    Alex Mourão Terzi

    2016-01-01

    Full Text Available En ese artículo se describen experiencias innovadoras con estudiantes y maestros brasileños en diferentes niveles educativos, además de nuevos proyectos en fase de implementación. Se concluye que las iniciativas y acciones aún se encuentran en sus pasos iniciales, pero con gran potencial de impacto y crecimiento. En su conjunto, pueden favorecer la visión de una educación basada en valores humanos y actitudes compasivas, preparando a nuestros jóvenes como futuros líderes en un nuevo mundo en constante evolución.

  10. TIROTOXICOSIS GESTACIONAL: PATOLOGIA CON RIESGO VITAL

    OpenAIRE

    Valdés R.,Enrique; Pilasi M.,Carlos; Núñez U.,Tatiana

    2003-01-01

    Se presenta un caso clínico con diagnóstico final de Tirotoxicosis gestacional que debuta con una complicación excepcional, insuficiencia cardíaca congestiva e hipertensión pulmonar severa. Se presenta la experiencia del Hospital Clínico de la Universidad de Chile, proponiendo que su diagnóstico y tratamiento oportunos son la base del pronóstico de esta patología de riesgo vital para el binomio madre-hijo

  11. Experimentos de química recreativa con sulfato de cobre pentahidratado

    Directory of Open Access Journals (Sweden)

    Santiago Heredia-Avalos

    2006-01-01

    Full Text Available En este trabajo se proponen varias experiencias sencillas usando sales de sulfato de cobre pentahidratado. Todas ellas pueden realizarse en casa con utensilios de cocina y usando sustancias baratas, la mayoría de las cuales pueden encontrarse en un supermercado. Las experiencias propuestas permiten estudiar el proceso de cristalización del sulfato de cobre pentahidratado, reacciones de oxidación-reducción, de formación de precipitados e, incluso, reacciones de formación de complejos. Estas experiencias pretenden despertar el interés de los alumnos por la química.

  12. Small-animal SPECT and SPECT/CT: application in cardiovascular research

    Energy Technology Data Exchange (ETDEWEB)

    Golestani, Reza; Dierckx, Rudi A.J.O. [University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); Wu, Chao [University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); University Medical Center Utrecht, Image Sciences Institute and Rudolf Magnus Institute of Neurosciences, Utrecht (Netherlands); Tio, Rene A. [University Medical Center Groningen, Thorax Center, Department of Cardiology, Groningen (Netherlands); University Medical Center Groningen, Cardiovascular Imaging Group, P.O. Box 30001, Groningen (Netherlands); Zeebregts, Clark J. [University Medical Center Groningen, Department of Surgery, Division of Vascular Surgery, Groningen (Netherlands); University Medical Center Groningen, Cardiovascular Imaging Group, P.O. Box 30001, Groningen (Netherlands); Petrov, Artiom D. [University of California, Irvine, Division of Cardiology, School of Medicine, Irvine, California (United States); Beekman, Freek J. [University Medical Center Utrecht, Image Sciences Institute and Rudolf Magnus Institute of Neurosciences, Utrecht (Netherlands); Delft University of Technology, Faculty of Applied Sciences, Section Radiation Detection and Medical Imaging, Delft (Netherlands); MILabs, Utrecht (Netherlands); Boersma, Hendrikus H. [University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); University Medical Center Groningen, Department of Clinical and Hospital Pharmacy, Hanzeplein 1, P.O. Box 30001, Groningen (Netherlands); University Medical Center Groningen, Cardiovascular Imaging Group, P.O. Box 30001, Groningen (Netherlands); Slart, Riemer H.J.A. [University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); University Medical Center Groningen, Cardiovascular Imaging Group, P.O. Box 30001, Groningen (Netherlands)

    2010-09-15

    Preclinical cardiovascular research using noninvasive radionuclide and hybrid imaging systems has been extensively developed in recent years. Single photon emission computed tomography (SPECT) is based on the molecular tracer principle and is an established tool in noninvasive imaging. SPECT uses gamma cameras and collimators to form projection data that are used to estimate (dynamic) 3-D tracer distributions in vivo. Recent developments in multipinhole collimation and advanced image reconstruction have led to sub-millimetre and sub-half-millimetre resolution SPECT in rats and mice, respectively. In this article we review applications of microSPECT in cardiovascular research in which information about the function and pathology of the myocardium, vessels and neurons is obtained. We give examples on how diagnostic tracers, new therapeutic interventions, pre- and postcardiovascular event prognosis, and functional and pathophysiological heart conditions can be explored by microSPECT, using small-animal models of cardiovascular disease. (orig.)

  13. Small-animal SPECT and SPECT/CT: application in cardiovascular research

    International Nuclear Information System (INIS)

    Golestani, Reza; Dierckx, Rudi A.J.O.; Wu, Chao; Tio, Rene A.; Zeebregts, Clark J.; Petrov, Artiom D.; Beekman, Freek J.; Boersma, Hendrikus H.; Slart, Riemer H.J.A.

    2010-01-01

    Preclinical cardiovascular research using noninvasive radionuclide and hybrid imaging systems has been extensively developed in recent years. Single photon emission computed tomography (SPECT) is based on the molecular tracer principle and is an established tool in noninvasive imaging. SPECT uses gamma cameras and collimators to form projection data that are used to estimate (dynamic) 3-D tracer distributions in vivo. Recent developments in multipinhole collimation and advanced image reconstruction have led to sub-millimetre and sub-half-millimetre resolution SPECT in rats and mice, respectively. In this article we review applications of microSPECT in cardiovascular research in which information about the function and pathology of the myocardium, vessels and neurons is obtained. We give examples on how diagnostic tracers, new therapeutic interventions, pre- and postcardiovascular event prognosis, and functional and pathophysiological heart conditions can be explored by microSPECT, using small-animal models of cardiovascular disease. (orig.)

  14. Experiencias formativas de jóvenes de la Universidad Intercultural de Chiapas

    Directory of Open Access Journals (Sweden)

    Diego Rodríguez Calderón de la Barca

    2016-04-01

    Full Text Available El presente texto expone las principales experiencias formativas deestudiantes y egresados/as de la Universidad Intercultural de Chiapas,San Cristóbal de las Casas (UNICH, México, en las que está implícita laarticulación de tres instituciones fundamentales en la reproducción social:la familia, la escuela (en este caso la universidad y el trabajo. Así, elobjetivo es reflexionar sobre las experiencias formativas que van marcandoa las y los jóvenes antes, durante y después de que ingresany egresan de la universidad. Son experiencias que están relacionadascon su tránsito y estancia en la universidad, pero también a otras externasal campus universitario, y a partir de las cuales también construyensu condición juvenil (social y subjetivamente. El texto está dividido entres partes. En la primera presento sintéticamente características delcontexto y población de estudio. En la segunda, de manera muy brevemenciono la perspectiva teórica y la metodología. Y en la tercera expongolas experiencias más trascendentes de acuerdo al análisis delestudio y con base en los testimonios de los jóvenes entrevistados.

  15. Myocardial Perfusion SPECT 2015 in Germany

    Science.gov (United States)

    Burchert, Wolfgang; Schäfer, Wolfgang; Hacker, Marcus

    2016-01-01

    Summary Aim The working group Cardiovascular Nuclear Medicine of the German Society of Nuclear Medicine presents the results of the 7th survey of myocardial perfusion SPECT (MPS) of the reporting year 2015. Method 268 questionnaires (173 practices [PR], 67 hospitals [HO], 28 university hospitals [UH]) were evaluated. Results of the last survey from 2012 are set in squared brackets. Results MPS of 121 939 [105 941] patients were reported. 98 % [95 %] of all MPS were performed with Tc-99m radiopharmaceuticals and 2 % [5 %] with Tl-201. 78 % [79 %] of all patients were studied in PR, 14 % [15 %] in HO, and 8 % [6 %] in UH. A pharmacological stress test was performed in 43 % [39 %] (22 % [24 %] adenosine, 20 % [9 %] regadenoson, 1% [6 %] dipyridamole or dobutamine). Attenuation correction was applied in 25 % [2009: 10 %] of MPS. Gated SPECT was performed in 78 % [70 %] of all rest MPS, in 80 % [73 %] of all stress and in 76 % [67 %] of all stress and rest MPS. 53 % [33 %] of all nuclear medicine departments performed MPS scoring by default, whereas 24 % [41 %] did not apply any quantification. 31 % [26 %] of all departments noticed an increase in their counted MPS and 29 % [29 %] no changes. Data from 89 departments which participated in all surveys showed an increase in MPS count of 11.1 % (PR: 12.2 %, HO: 4.8 %, UH: 18.4 %). 70 % [60 %] of the MPS were requested by ambulatory care cardiologists. Conclusion The 2015 MPS survey reveals a high-grade adherence of routine MPS practice to current guidelines. The positive trend in MPS performance and number of MPS already observed in 2012 continues. Educational training remains necessary in the field of SPECT scoring. PMID:27909712

  16. Arquitectura para aguijonear la experiencia de conocer en la escuela

    Directory of Open Access Journals (Sweden)

    Diego Emilio Clementin

    2017-09-01

    Full Text Available El presente artículo es una invitación para que los docentes asumamos el desafío de afirmarnos como media­dores de cultura en el marco de un vínculo pedagógico no autoritario, esto significa asumir la responsabilidad de transmitir conocimientos, aguijonear la experiencia de conocer; ulteriormente, el alumno hará con esos co­nocimientos lo que quiera, pueda o necesite, pero luego de haberlos tenido a disposición. Para desarrollar un tema, en el marco de un vínculo pedagógico no autoritario que pueda aguijonear la experiencia de conocer de los alumnos, se sugiere considerar las fases de construcción, elaboración, ejercitación y aplicación durante las clases, no de manera aislada, sino muy articuladas entre sí. 

  17. Generation of complete electronic nuclear medicine reports including static, dynamic and gated images

    International Nuclear Information System (INIS)

    Beretta, M.; Pilon, R.; Mut, F.

    2002-01-01

    Aim: To develop a procedure for the creation of nuclear medicine reports containing static and dynamic images. The reason for implementing this technique is the lack of adequate solutions for an electronic format of nuclear medicine results allowing for rapid transmission via e-mail, specially in the case of dynamic and gated SPECT studies, since functional data is best presented in dynamic mode. Material and Methods: Clinical images were acquired in static, whole body, dynamic and gated mode, corresponding to bone studies, diuretic renogram, radionuclide cystography and gated perfusion SPECT, as well as respective time-activity curves. Image files were imported from a dedicated nuclear medicine computer system (Elscint XPert) to a Windows-based PC through a standard ethernet network with TCP-IP communications protocol, using a software developed by us which permits the conversion from the manufacturer's original format into a bitmap format (.bmp) compatible with commercially available PC software. For cardiac perfusion studies, background was subtracted prior to transferring to reduce the amount of information in the file; this was not done for other type of studies because useful data could be eliminated. Dynamic images were then processed using commercial software to create animated files and stored in .gif format. Static images were re-sized and stored in .jpg format. Original color or gray scale was always preserved. All the graphic material was then merged with a previously prepared report text using HTML format. The report also contained reference diagrams to facilitate interpretation. The whole report was then compressed into a self-extractable file, ready to be sent by electronic mail. Reception of the material was visually checked for data integrity including image quality by two experienced nuclear medicine physicians. Results: The report presented allows for simultaneous visualization of the text, diagrams and images either static, dynamic, gated or

  18. Rehabilitación integral de barriadas con dificultades sociales en Andalucía. La experiencia de San Martín de Porres en Córdoba

    Directory of Open Access Journals (Sweden)

    Morón Serna, E.

    2015-03-01

    Full Text Available The recovery of the districts built during the second half of the twentieth century, especially those with greater social difficulties, constitutes a sustainable alternative to the failure of continuous urban growth. It is essential to promote integral actions in order to correct both deficiencies and deterioration in residential buildings, improve the relationship of these areas with their urban environments, provide them with facilities and high quality public spaces, as well as to encourage local civil community involvement. On the basis of the experiences and tools that have been developed over the past decade in Andalusia, this paper analyzes the integral renovation of the so called San Martin de Porres district. Here we study its urban and architectural development –standing out the work of the architect Rafael de La-Hoz– as well as the social transformations of its population. From the study of the design, management and execution of its renovation the most relevant aspects are deduced with the objective of facilitating their consideration in future renovation policies.La recuperación de barriadas construidas en la segunda mitad del siglo XX, especialmente aquellas con mayores dificultades sociales, constituye una alternativa sostenible al fracaso del continuo crecimiento urbano. Es necesario promover actuaciones integrales que corrijan el deterioro y carencias de edificios residenciales, mejoren las relaciones de estos ámbitos con sus entornos urbanos, los doten de equipamientos y espacios públicos de calidad e impulsen la participación vecinal y su desarrollo social y económico. A partir de experiencias e instrumentos desarrollados en la última década en Andalucía, se analiza la rehabilitación integral de la barriada de San Martín de Porres en Córdoba. Se aborda su desarrollo urbanístico y arquitectónico –donde sobresale la figura de Rafael de La-Hoz– y las transformaciones sociales de su población. Del dise

  19. The consequences of a new software package for the quantification of gated-SPECT myocardial perfusion studies

    International Nuclear Information System (INIS)

    Veen, Berlinda J. van der; Dibbets-Schneider, Petra; Stokkel, Marcel P.M.; Scholte, Arthur J.

    2010-01-01

    Semiquantitative analysis of myocardial perfusion scintigraphy (MPS) has reduced inter- and intraobserver variability, and enables researchers to compare parameters in the same patient over time, or between groups of patients. There are several software packages available that are designed to process MPS data and quantify parameters. In this study the performances of two systems, quantitative gated SPECT (QGS) and 4D-MSPECT, in the processing of clinical patient data and phantom data were compared. The clinical MPS data of 148 consecutive patients were analysed using QGS and 4D-MSPECT to determine the end-diastolic volume, end-systolic volume and left ventricular ejection fraction. Patients were divided into groups based on gender, body mass index, heart size, stressor type and defect type. The AGATE dynamic heart phantom was used to provide reference values for the left ventricular ejection fraction. Although the correlations were excellent (correlation coefficients 0.886 to 0.980) for all parameters, significant differences (p < 0.001) were found between the systems. Bland-Altman plots indicated that 4D-MSPECT provided overall higher values of all parameters than QGS. These differences between the systems were not significant in patients with a small heart (end-diastolic volume <70 ml). Other clinical factors had no direct influence on the relationship. Additionally, the phantom data indicated good linear responses of both systems. The discrepancies between these software packages were clinically relevant, and influenced by heart size. The possibility of such discrepancies should be taken into account when a new quantitative software system is introduced, or when multiple software systems are used in the same institution. (orig.)

  20. Resultados de SPECT miocárdico y eventos cardiovasculares en dos servicios de Medicina nuclear de Bogotá durante 2011 a 2012

    Directory of Open Access Journals (Sweden)

    Leonardo Cadavid

    2014-03-01

    Conclusiones: Un estudio SPECT miocárdico normal se asocia con incidencia reducida de eventos cardiovasculares mayores en el seguimiento a un año, aun en pacientes con características clínicas de alto riesgo.

  1. Las violencias y los jóvenes universitarios, una experiencia para reflexionar

    Directory of Open Access Journals (Sweden)

    Noemí Ehrenfeld Lenkiewicz

    2016-01-01

    Full Text Available Este artículo pone de manifiesto aspectos poco o nada explorados de los estudiantes universitarios en relación con las violencias presentes en su cotidianidad, que afectan el desarrollo de su vida académica. A partir de una investigación sobre la percepción y las experiencias de las violencias en diferentes ámbitos se analiza el contexto que se vive en México y la participación de los jóvenes en las casuísticas. Las respuestas de los entrevistados que abordan experiencias propias brindan elementos que exigen pensar en una transformación educativa y pedagógica basada en la adquisición de habilidades para la vida.

  2. Validation of the Gate simulation platform in single photon emission computed tomography and application to the development of a complete 3-dimensional reconstruction algorithm; Validation de la plate-forme de simulation GATE en tomographie a emission monophotonique et application au developpement d'un algorithme de reconstruction 3D complete

    Energy Technology Data Exchange (ETDEWEB)

    Lazaro, D

    2003-10-01

    Monte Carlo simulations are currently considered in nuclear medical imaging as a powerful tool to design and optimize detection systems, and also to assess reconstruction algorithms and correction methods for degrading physical effects. Among the many simulators available, none of them is considered as a standard in nuclear medical imaging: this fact has motivated the development of a new generic Monte Carlo simulation platform (GATE), based on GEANT4 and dedicated to SPECT/PET (single photo emission computed tomography / positron emission tomography) applications. We participated during this thesis to the development of the GATE platform within an international collaboration. GATE was validated in SPECT by modeling two gamma cameras characterized by a different geometry, one dedicated to small animal imaging and the other used in a clinical context (Philips AXIS), and by comparing the results obtained with GATE simulations with experimental data. The simulation results reproduce accurately the measured performances of both gamma cameras. The GATE platform was then used to develop a new 3-dimensional reconstruction method: F3DMC (fully 3-dimension Monte-Carlo) which consists in computing with Monte Carlo simulation the transition matrix used in an iterative reconstruction algorithm (in this case, ML-EM), including within the transition matrix the main physical effects degrading the image formation process. The results obtained with the F3DMC method were compared to the results obtained with three other more conventional methods (FBP, MLEM, MLEMC) for different phantoms. The results of this study show that F3DMC allows to improve the reconstruction efficiency, the spatial resolution and the signal to noise ratio with a satisfactory quantification of the images. These results should be confirmed by performing clinical experiments and open the door to a unified reconstruction method, which could be applied in SPECT but also in PET. (author)

  3. Factores de éxito de las alianzas para el desarrollo local. Experiencias comparadas de España y Perú

    Directory of Open Access Journals (Sweden)

    Elsa Del Castillo Mory

    2009-06-01

    Full Text Available Las alianzas se forman con el objetivo de superar las limitaciones que los socios enfrentan para lograr ciertas metas. Cuando la meta en cuestión es promover el desarrollo local, se requiere del concurso de una serie de agentes sociales: empresa privada, gobierno local, asociaciones civiles, grupos comunitarios, entre otros. Este artículo busca, mediante el análisis comparativo de tres experiencias de desarrollo local o comarcal1 lideradas por el distrito de Villa El Salvador (Lima-Perú, la empresa minera Yanacocha (CajamarcaPerú y la Agencia Española de Desarrollo Iraugi Lantzen (País Vasco-España, identificar los factores determinantes del éxito de los acuerdos de cooperación para el desarrollo local. Creemos que un mejor conocimiento de los factores asociados con el éxito de las alianzas podría ayudar a quienes se plantean el reto de buscar posibles socios, así como a aquellos preocupados por una administración efectiva de las alianzas en marcha. El caso de Villa El Salvador evidencia cómo el apoyo gubernamental fue fundamental para la formación del distrito, aunque los logros de esta agrupación no podrían explicarse sin la participación activa de la comunidad. Por otro lado, la experiencia de la empresa Yanacocha recuerda al lector que todavía existe un camino muy grande por recorrer en el Perú en lo que se refiere a la articulación de los esfuerzos de la empresa privada con otros agentes sociales, y que es necesario aprender de las experiencias de quienes han recorrido parte de este camino. Un caso con matices diferentes es el que se ilustra con la experiencia de la agencia española Iraugi Lantzen, que destaca los retos y las oportunidades que surgen a partir de un trabajo concertado entre entidades municipales que buscan el desarrollo local. En suma, se puede afirmar que, si bien existen condiciones de contexto y coyunturales que favorecen la conformación de alianzas de cooperación para el desarrollo, hay otros

  4. [Follow-up of patients with good exercise capacity in stress test with myocardial single-photon emission computed tomography (SPECT)].

    Science.gov (United States)

    González, Javiera; Prat, Hernán; Swett, Eduardo; Berrocal, Isabel; Fernández, René; Zhindon, Juan Pablo; Castro, Ariel; Massardo, Teresa

    2015-11-01

    The evaluation of coronary artery disease (CAD) can be performed with stress test and myocardial SPECT tomography. To assess the predictive value of myocardial SPECT using stress test for cardiovascular events in patients with good exercise capacity. We included 102 males aged 56 ± 10 years and 19 females aged 52 ± 10 years, all able to achieve 10 METs and ≥ 85% of the theoretical maximum heart rate and at least 8 min in their stress test with gated 99mTc-sestamibi SPECT. Eighty two percent of patients were followed clinically for 33 ± 17 months. Sixty seven percent of patients were studied for CAD screening and the rest for known disease assessment. Treadmill stress test was negative in 75.4%; 37% of patients with moderate to severe Duke Score presented ischemia. Normal myocardial perfusion SPECT was observed in 70.2%. Reversible defects appeared in 24.8% of cases, which were of moderate or severe degree (> 10% left ventricular extension) in 56.6%. Only seven cases had coronary events after the SPECT. Two major (myocardial infarction and emergency coronary revascularization) and 5 minor events (elective revascularization) ere observed in the follow-up. In a multivariate analysis, SPECT ischemia was the only statistically significant parameter that increased the probability of having a major or minor event. Nearly a quarter of our patients with good exercise capacity demonstrated reversible defects in their myocardial perfusion SPECT. In the intermediate-term follow-up, a low rate of cardiac events was observed, being the isotopic ischemia the only significant predictive parameter.

  5. Algunas experiencias de aplicación del aprendizaje cooperativo y del aprendizaje basado en proyectos

    OpenAIRE

    García-Almiñana, Daniel; Amante García, Beatriz

    2006-01-01

    En esta comunicación se pretenden presentar algunas experiencias de aplicación del AC y ABP en distintas asignaturas impartidas en la Universidad Europea de Madrid y en la Universidad Politécnica de Catalunya, destacando los aspectos de mejora observados con respecto a la docencia convencional.

  6. EXPERIENCIAS PSICOSEXUALES DE PACIENTES HISTERECTOMIZADAS DEL SERVICIO DE GINECOLOGÍA DEL HOSPITAL REGIONAL DOCENTE LAS MERCEDES – CHICLAYO 2013

    OpenAIRE

    Núñez Manayay, Tania Mercedes; Universidad Señor de Sipán; Vera Ñañez, Huendy Jame; Universidad Señor de Sipán

    2014-01-01

     La presente investigación cualitativa titulada Experiencias psicosexuales de pacientes histerectomizadas del servicio de Ginecología del Hospital Regional Docente las Mercedes – Chiclayo 2013 tuvo como objetivo describir las experiencias psicosexuales de pacientes histerectomizadas. Con diseño estudio de caso; la muestra conformada por siete pacientes post histerectomizadas de seis meses a un año; en la recolección de datos se utilizó la observación y la entrevista semiestructurada, las que ...

  7. Validation of the Gate simulation platform in single photon emission computed tomography and application to the development of a complete 3-dimensional reconstruction algorithm

    International Nuclear Information System (INIS)

    Lazaro, D.

    2003-10-01

    Monte Carlo simulations are currently considered in nuclear medical imaging as a powerful tool to design and optimize detection systems, and also to assess reconstruction algorithms and correction methods for degrading physical effects. Among the many simulators available, none of them is considered as a standard in nuclear medical imaging: this fact has motivated the development of a new generic Monte Carlo simulation platform (GATE), based on GEANT4 and dedicated to SPECT/PET (single photo emission computed tomography / positron emission tomography) applications. We participated during this thesis to the development of the GATE platform within an international collaboration. GATE was validated in SPECT by modeling two gamma cameras characterized by a different geometry, one dedicated to small animal imaging and the other used in a clinical context (Philips AXIS), and by comparing the results obtained with GATE simulations with experimental data. The simulation results reproduce accurately the measured performances of both gamma cameras. The GATE platform was then used to develop a new 3-dimensional reconstruction method: F3DMC (fully 3-dimension Monte-Carlo) which consists in computing with Monte Carlo simulation the transition matrix used in an iterative reconstruction algorithm (in this case, ML-EM), including within the transition matrix the main physical effects degrading the image formation process. The results obtained with the F3DMC method were compared to the results obtained with three other more conventional methods (FBP, MLEM, MLEMC) for different phantoms. The results of this study show that F3DMC allows to improve the reconstruction efficiency, the spatial resolution and the signal to noise ratio with a satisfactory quantification of the images. These results should be confirmed by performing clinical experiments and open the door to a unified reconstruction method, which could be applied in SPECT but also in PET. (author)

  8. Expectativas y experiencias de uso de las mujeres gitanas mayores ante los servicios sanitarios de atención primaria

    Directory of Open Access Journals (Sweden)

    Antonio Jesús Ramos-Morcillo

    2015-04-01

    Conclusiones: Las mujeres gitanas mayores plantean sus expectativas y experiencias en los servicios de AP alrededor del binomio enfermedad/médico. Esperan una atención basada en la confianza y con una alta instrumentalización. Se observa un discurso con signos de cambio dirigidos hacia una participación más activa y reivindicativa en los servicios de AP.

  9. SPECT in psychiatry; Die Bedeutung der Hirn-SPECT in der Psychiatrie

    Energy Technology Data Exchange (ETDEWEB)

    Kasper, S [Universitaetsklinik fuer Psychiatrie, Wien (Austria); Gruenwald, F [Bonn Univ. (Germany). Klinik fuer Nuklearmedizin; Danos, P [Psychiatrische Universitaetsklinik, Bonn (Germany); Walter, H [Universitaetsklinik fuer Psychiatrie, Wien (Austria); Klemm, E [Bonn Univ. (Germany). Klinik fuer Nuklearmedizin; Bruecke, T [Universitaetsklinik fuer Neurologie, Wien (Austria); Podreka, I [Universitaetsklinik fuer Neurologie, Wien (Austria); Biersack, H J [Bonn Univ. (Germany). Klinik fuer Nuklearmedizin

    1994-10-01

    In the last fifteen years different attempts have been undertaken to understand the biological basis of major psychiatric disorders. One important tool to determine patterns of brain dysfunction is single emission computed tomography (SPECT). Whereas SPECT investigations are already a valuable diagnostic instrument for the diagnosis of dementia of the Alzheimer Type (DAT) there have not been consistent findings that can be referred to as specific for any other particular psychiatric diagnostic entity. Nevertheless, SPECT studies have been able to demonstrate evidence of brain dysfunction in patients with schizophrenia, depression, anxiety disorders, and substance abuse in which other methods showed no clear abnormality of brain function. Our manuscript reviews the data which are currently available in the literature and stresses the need for further studies, especially for prediction and monitoring psychiatric treatment modalities. (orig.) [Deutsch] In den vergangenen 15 Jahren wurde durch verschiedene methodologische Ansaetze versucht, die biologischen Ursachen psychiatrischer Erkrankungen naeher zu erforschen. Als eine bedeutende Methode hat sich dabei die Single-Photonen-Emissions-Computertomographie (SPECT) herausgestellt. Waehrend die SPECT-Untersuchungen bereits Eingang in die Routinediagnostik bei Demenzen vom Alzheimer-Typ gefunden haben, konnten fuer weitere psychiatrische Erkrankungen noch keine eindeutigen Befunde etabliert werden. Mit der SPECT-Methode ist es jedoch gelungen, funktionelle Veraenderungen des Gehirns von psychiatrischen Erkrankungen darzustellen, wie z.B. Schizophrenie, Depression, Angsterkrankungen bzw. Substanzmissbrauch. In Forschungsprotokollen wird durch die SPECT-Methode versucht, abzuklaeren, inwieweit es moeglich ist, innerhalb der Erkrankungsentitaeten psychiatrischer Erkrankungen oder auch diese uebergreifend eine Subklassifizierung zu finden und evtl. Gehirnsysteme ausfindig zu machen, die mit einer spezifischen

  10. Timectomía como tratamiento de miastenia gravis: Experiencia en el Hospital Nacional Dos de Mayo. Lima, Perú

    Directory of Open Access Journals (Sweden)

    Julio VASQUEZ KOBASHIGAWA

    2006-10-01

    Full Text Available La timectomía es una opción terapéutica en el manejo de la miastenia gravis (MG. Aunque existe controversia sobre las indicaciones quirúrgicas y el mejor momento para operar, la timectomía se mantiene como un procedimiento seguro y efectivo para el tratamiento de MG. Aquí revisamos nuestra experiencia con esta operación en pacientes con esta enfermedad, y comparamos nuestros resultados con aquellos publicados en la literatura.

  11. Experiencias exitosas de e- learning en la universidad gallega

    OpenAIRE

    Gromaz Campos, Manuel; Rodríguez Malmierca, María José; García Tobío, Javier

    2008-01-01

    Este artículo resume la información obtenida en el marco de un proyecto de investigación, denominado "Observatorio gallego de e-learning". Dicha investigación fue dirigida por el Centro de Supercomputación de Galicia, con la participación activa de las tres universidades gallegas. Su principal objetivo fue realizar un análisis en profundidad sobre el estado del e-learning tanto en la universidad como en la empresa gallegas. Entre los elementos analizados, se encuentran algunas experiencias qu...

  12. Mujeres violentadas durante el embarazo y el parto: experiencias de parteras en Jalisco, México

    OpenAIRE

    Villaseñor F, Martha; Laureano E, Jorge; Mejía M, Martha L; Valadez F, Isabel; Márquez A, José M; González A, Jaime A

    2014-01-01

    OBJETIVO: explorar la experiencia y perspectiva de parteras con mujeres violentadas durante el embarazo y el parto en Jalisco, México. METODOLOGIA: se llevó a cabo un estudio cualitativo en zona rural de Jalisco, México, entre mayo y octubre de 2011 con 24 parteras, utilizando la entrevista individual, modalidad historia de vida pautada y la asamblea participativa regional como técnicas de indagación; posteriormente, los discursos fueron analizados bajo el modelo actancial semiótico. RESULTAD...

  13. Enfoque fenomenológico de la crítica arquitectónica: el rol de la experiencia sensible.

    Directory of Open Access Journals (Sweden)

    Dra. Arq. Sandra Navarrete

    2016-07-01

    Full Text Available El objetivo central de este trabajo fue defnir un método crítico de análisis de la arquitectura que se centre en la experiencia sensible como herramienta de estudio de los aspectos estéticos. Se propone con una validación empírica que permita su generalización. Se realizó un recorte epistemológico situándose en el paradigma posmoderno de la estética. Para la comprensión de los factores que modifcan la arquitectura regional, se tomó como objeto de análisis la experiencia espacial de las bodegas de Mendoza. Se sostiene como hipótesis principal que la interpretación crítica de la arquitectura a través de la fenomenología permite un mayor grado de sensibilidad en la concepción de espacios y por lo tanto el aprendizaje de un método de proyecto con aspectos más vinculados al hombre. A partir del análisis realizado de tres bodegas locales con estudiantes de cuarto año de la carrera de arquitectura de la Universidad Nacional de Cuyo, se observó que las vivencias espaciales tienen un alto nivel de pregnancia. Por ello, es posible afrmar que la experiencia sensorial es un aspecto relevante en la formación de una postura conceptual de interés para todas las instancias del proyecto arquitectónico

  14. El valor de los apoyos para el bienestar subjetivo al vivir con esquizofrenia

    Directory of Open Access Journals (Sweden)

    Daniel Ricardo Zaraza Morales

    Full Text Available Este artículo es el resultado de una investigación cualitativa que se realizó con la participación de un grupo de personas con esquizofrenia y sus familiares, en Medellín (Colombia. El objetivo fue comprender los aspectos que promueven la salud mental en las personas con esquizofrenia y sus familias, teniendo en cuenta su experiencia subjetiva. Se realizaron ocho entrevistas en profundidad y dos grupos focales para la recolección de la información, la cual se analizó bajo los planteamientos de la Teoría Fundamentada de Strauss y Corbin. La categoría interpretativa que surgió durante el análisis fue "El valor de los apoyos, un punto subjetivo en la experiencia de vivir con esquizofrenia", la cual revela la importancia que tiene, para quienes viven y conviven con la enfermedad, el fortalecimiento de los apoyos personales, familiares y sociales disponibles, pues estos favorecen la sensación de bienestar y el camino hacia la recuperación.

  15. A small-animal imaging system capable of multipinhole circular/helical SPECT and parallel-hole SPECT

    International Nuclear Information System (INIS)

    Qian Jianguo; Bradley, Eric L.; Majewski, Stan; Popov, Vladimir; Saha, Margaret S.; Smith, Mark F.; Weisenberger, Andrew G.; Welsh, Robert E.

    2008-01-01

    We have designed and built a small-animal single-photon emission computed tomography (SPECT) imaging system equipped with parallel-hole and multipinhole collimators and capable of circular or helical SPECT. Copper-beryllium parallel-hole collimators suitable for imaging the ∼35 keV photons from the decay of 125 I have been built and installed to achieve useful spatial resolution over a range of object-detector distances and to reduce imaging time on our dual-detector array. To address the resolution limitations in the parallel-hole SPECT and the sensitivity and limited field of view of single-pinhole SPECT, we have incorporated multipinhole circular and helical SPECT in addition to expanding the parallel-hole SPECT capabilities. The pinhole SPECT system is based on a 110 mm diameter circular detector equipped with a pixellated NaI(Tl) scintillator array (1x1x5 mm 3 /pixel). The helical trajectory is accomplished by two stepping motors controlling the rotation of the detector-support gantry and displacement of the animal bed along the axis of rotation of the gantry. Results obtained in SPECT studies of various phantoms show an enlarged field of view, very good resolution and improved sensitivity using multipinhole circular or helical SPECT. Collimators with one, three and five, 1-mm-diameter pinholes have been implemented and compared in these tests. Our objective is to develop a system on which one may readily select a suitable mode of either parallel-hole SPECT or pinhole circular or helical SPECT for a variety of small animal imaging applications

  16. Aspectos significativos surgidos de la experiencia de haber sido responsable de un evento adverso en salud

    Directory of Open Access Journals (Sweden)

    Augusto Hernán Ferreira-Umpiérrez

    2014-01-01

    Full Text Available Objetivo: conocer los aspectos significativos para las enfermeras sobre su experiencia de haber sido responsables de un evento ad- verso en salud. Materiales y métodos: estudio cualitativo exploratorio, con el enfoque de la hermenéutica dialéctica. Se utilizó la técnica de análisis de contenido. Muestra constituida por doce enfermeras que tuvieron al menos una experiencia de responsabilidad ante un evento adverso con un paciente, y por cuatro supervisores de enfermería con responsabilidad de supervisión al ocurrir el evento adverso. Resultados: bajo el enfoque de la hermenéutica dialéctica, el análisis de los datos permitió construir las siguientes categorías relacio- nadas con la organización de salud y los recursos humanos: el contexto organizacional, el desconocimiento del proceso de notifi cación, la sobrecarga de trabajo, la ausencia de descanso. Conclusiones: reconocer la importancia del contexto organizacional donde se desarrollan los cuidados, el desconocimiento del proceso de notificación como aspecto por mejorar, la sobrecarga de trabajo y la ausencia d e descanso del personal. Es necesario profundizar en el tema mediante investigaciones y desarrollo de intervenciones que promuevan la cult ura de seguridad en la atención sanitaria, con implicaciones en la práctica y para la formación de las enfermeras.

  17. FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS CON VIH/SIDA AL ACCEDER SERVICIOS DE SALUD

    Science.gov (United States)

    RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS

    2013-01-01

    RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas con VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. Con el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599

  18. Indeterminate lesions on planar bone scintigraphy in lung cancer patients: SPECT, CT or SPECT-CT?

    International Nuclear Information System (INIS)

    Sharma, Punit; Kumar, Rakesh; Singh, Harmandeep; Bal, Chandrasekhar; Malhotra, Arun; Julka, Pramod Kumar; Thulkar, Sanjay

    2012-01-01

    The objective of the present study was to compare the role of single photon emission computed tomography (SPECT), computed tomography (CT) and SPECT-CT of selected volume in lung cancer patients with indeterminate lesions on planar bone scintigraphy (BS). The data of 50 lung cancer patients (53 ± 10.3 years; range 30-75; male/female 38/12) with 65 indeterminate lesions on planar BS (January 2010 to November 2010) were retrospectively evaluated. All of them underwent SPECT-CT of a selected volume. SPECT, CT and SPECT-CT images were independently evaluated by two experienced readers (experience in musculoskeletal imaging, including CT: 5 and 7 years) in separate sessions. A scoring scale of 1 to 5 was used, in which 1 is definitely metastatic, 2 is probably metastatic, 3 is indeterminate, 4 is probably benign and 5 is definitely benign. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for each modality, taking a score ≤2 as metastatic. With receiver operating characteristic (ROC) curve analysis, areas under the curve (AUC) were calculated for each modality and compared. Clinical and imaging follow-up and/or histopathology were taken as reference standard. For both readers SPECT was inferior to CT (P = 0.004, P = 0.022) and SPECT-CT (P = 0.003, P = 0.037). However, no significant difference was found between CT and SPECT-CT for reader 1 (P = 0.847) and reader 2 (P = 0.592). The findings were similar for lytic as well as sclerotic lesions. Moderate inter-observer agreement was seen for SPECT images (κ = 0.426), while almost perfect agreement was seen for CT (κ = 0.834) and SPECT-CT (κ = 0.971). CT alone and SPECT-CT are better than SPECT for accurate characterisation of indeterminate lesions on planar BS in lung cancer patients. CT alone is not inferior to SPECT-CT for this purpose and might be preferred because of shorter acquisition time and wider availability. (orig.)

  19. Experiencias formativas, auto-adscripciones y conflictos ambientales en el sudoeste de Misiones (Argentina

    Directory of Open Access Journals (Sweden)

    Ana Padawer

    2015-04-01

    Full Text Available En este artículo abordaremos cómo se relacionan las experiencias formativas vinculadas al trabajo rural, las identificaciones y los conflictos ambientales en San Ignacio, Misiones (Argentina. Nos interesa problematizar cómo los aprendizajes ligados a las tareas rurales se vinculan con las auto-adscripciones de los sujetos, teniendo como referencia las categorías de actores sociales agrarios regionales y las denominaciones que provienen de agendas estatales de intervención. Estos procesos acontecen en un contexto de creciente concentración de propiedades que se destinan a la explotación forestal, donde observamos, en algunos casos, cierta ambientalización de los históricos conflictos territoriales.Utilizando materiales provenientes de un trabajo de campo etnográfico que iniciamos en 2008, presentaremos a dos familias de pobladores rurales. En ambos casos es posible ver cómo el acceso a la tierra es decisivo para las experiencias formativas en las actividades de reproducción social, y que se liga con identificaciones como “gente de la colonia” y una incipiente referencia a la “agricultura familiar” a partir de las intervenciones del Estado. Estas dos familias permiten mostrar cómo las experiencias e identificaciones se expresan en el contexto de la participación de los sujetos en conflictos sociales, que asumen en un caso la forma histórica de reclamos fundiarios mientras que, en el otro, es posible ver que el ambiente tiene protagonismo incipiente.

  20. Diseño experimental de un sumidero de CO2 y sus implicaciones en el cambio climático. Una experiencia de trabajo con alumnos en el laboratorio de Educación Secundaria

    Directory of Open Access Journals (Sweden)

    Raquel Boronat-Gil

    2018-01-01

    Full Text Available El desarrollo teórico del cambio climático en el aula de Educación Secundaria requiere de experiencias recreativas que demuestren –in situ– diferentes aspectos del proceso global. La presente comunicación muestra una actividad de laboratorio, y el consiguiente trabajo del alumnado, para comprobar la reducción de gases de efecto invernadero mediante la aplicación de una tecnología básica, de bajo costo y que puede realizarse con materiales disponibles en cualquier laboratorio escolar. La analogía didáctica llevada a cabo entre el CO2 producido por el metabolismo microbiano dentro de una botella cerrada y su reacción con una base fuerte generadora de una presión inferior a la atmosférica (como consecuencia de la reacción del dióxido de carbono con una base, visible con un sencillo manómetro en U, será objeto de debate entre profesor-alumno, analizándose y especulando su captura con la repercusión a nivel mundial de mejora en el calentamiento global.

  1. Assessment of global and regional LV function obtained by quantitative gated SPECT using {sup 99m}Tc-tetrofosmin. Comparison with left ventricular cineangiography and echocardiography

    Energy Technology Data Exchange (ETDEWEB)

    Ban, Kazunobu; Nakajima, Toru; Aoki, Naoto; Abe, Sumihisa; Handa, Shunnosuke; Suzuki, Yutaka [Tokai Univ., Isehara, Kanagawa (Japan). School of Medicine

    1998-11-01

    The quantitative gated SPECT (QGS) software that has automatic edge detection algorithm of the left ventricle, is able to calculate LV volumes and visualize LV wall motion with perfusion throughout the cardiac cycle. We evaluated the reliability of global and regional LV function derived from QGS using {sup 99m}Tc-tetrofosmin by comparing with left ventricular cineangiography (LVG) and echocardiography (ECHO). In 22 cardiac patients, end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (LVEF) were calculated. Using cinematic display, regional LV wall motion were scored on a 3-point scale (1=normal, 2=hypokinesis, 3=akinesis; WMS). EDV, ESV and LVEF correlated well with those by LVG (p<0.001 for each). Correlation between WMS derived from QGS and ECHO was high (r=0.85, p<0.001). There was an inverse correlation between WMS and LVEF (r=0.77, p<0.001). In conclusion, QGS is useful to evaluate global LV function. Regional wall motion evaluated by QGS is good enough for clinical application. (author)

  2. Validation of use of the low energies library in the GATE program: assessment of the effective mass attenuation coefficient

    International Nuclear Information System (INIS)

    Argenta, J.; Brambilla, C.R.; Marques da Silva, A.M.; Hoff, G.

    2009-01-01

    GATE (Geant4 Application for Emission Tomography) is a versatile tool kit for nuclear medicine simulations of SPECT and PET studies. GATE takes advantage of well-validated libraries of physics processes models, geometry description, tracking of particles through materials, response of detector and visualization tools offered by Geant4. One package available to simulate electromagnetic interactions is LEP (Low Energy Electromagnetic Processes). The purpose of this work was to evaluate the LEP package used by GATE 4 for nuclear medicine shielding simulations. Several simulations were made involving a mono directional and 140 keV monoenergetic point source beam, passing through barriers of variable thickness of water and lead. The results showed good agreement with the theoretical model, indicating that GATE 4 uses correctly the LEP package. (author)

  3. La experiencia en Buchenwald. Estudio comparativo de cinco obras de Jorge Semprún

    OpenAIRE

    Serrano Garrido, Silvia María

    2017-01-01

    Este Trabajo Fin de Máster consiste en un estudio comparativo de las cinco obras de tema concentracionario del escritor e intelectual español Jorge Semprún, el cual fue víctima del régimen nazi entre los años 1943-1945. En estas fechas estuvo deportado en el campo de concentración de Buchenwald, pero sobrevivió para poder contar su experiencia como testigo directo en El largo viaje, Aquel domingo, La escritura o la vida, Viviré con su nombre, morirá con el mío y Ejercicios de supervivencia. ...

  4. Observación Electoral: Experiencia de la MOE Regional Valle del Cauca, Elecciones Nacionales de Colombia 2010

    OpenAIRE

    Escobar Higuera, Katherine

    2013-01-01

    En el presente artículo se reseña la experiencia de Observación electoral en el departamento del Valle del Cauca, por parte de la Misión de Observación Electoral MOE regional Valle. Con el propósito de visibilizar el trabajo de una red de organizaciones y personas que han tomado iniciativa en el mejoramiento de un proceso importante para el sistema democrático colombiano, las elecciones. Al reseñar esta experiencia, se espera sea referente de una acción de participación política desde las org...

  5. Experiencias y expectativas en el debate político. Jóvenes de Manizales y elecciones

    Directory of Open Access Journals (Sweden)

    Juana Ramírez-Castro

    2014-01-01

    Full Text Available En este artículo se presentan los resultados de una investigación exploratoria realizada durante la segunda ronda del debate electoral del 2010 en Colombia, y que tenía el objetivo de comprender el proceso deliberativo propio del debate público de lo que fue llamado en este estudio, el «sistema elector joven». Esta investigación, diseñada a la sombra de la Teoría de los Sistemas Sociales de Niklas Luhmann, recurrió a grupos focales y a entrevistas semiestructuradas realizadas con jóvenes votantes de la ciudad de Manizales para observar los “sentidos” que, como «experiencias» y «expectativas», soportaban las operaciones del sistema. Según lo observado, gran parte del debate electoral se realizó desde experiencias directas o de socialización y, contrario a la tendencia sobre el tema, las experiencias de socialización virtual tuvieron poca injerencia en la deliberación.

  6. Effects of perfusion detect on the measurement of left ventricular mass, ventricular volume and post-stress left ventricular ejection fraction in gated myocardial perfusion SPECT

    International Nuclear Information System (INIS)

    Ahn, Byeong Cheol; Bae, Sun Keun; Lee, Sang Woo; Jeong, Sin Young; Lee, Jae Tae; Lee, Kyu Bo

    2002-01-01

    The presence of perfusion defect may influence the left ventricular mass (LVM) measurement by quantitative gated myocardial perfusion SPECT (QGS), and ischemic myocardium, usually showing perfusion defect may produce post-stress LV dysfunction. This study was aimed to evaluated the effects of extent and reversibility of perfusion defect on the automatic measurement of LVM by QGS and to investigate the effect of reversibility of perfusion defect on post-stress LV dysfunction. Forty-six patients (male/female=34:12, mean age=64 years) with perfusion defect on myocardial perfusion SPECT underwent rest and post-stress QGS. Forty patients (87%) showed reversible defect. End-diastolic volume (EDV), end-systolic volume (ESV), LV ejection fraction (EF), and LV myocardial volume were obtained from QGS by autoquant program, and LVM was calculated by multiplying the LV myocardial volume by the specific gravity of myocardium. LVMs measured at rest and post-stress QGS showed good correlation, and higher correlation was founded in the subjects with fixed perfusion defect and with small defect (smaller than 20%). There were no significant differences in EDVs, ESVs and EFs between obtained by rest and post-stress QGS in patients with fixed myocardial defect. Whereas, EF obtained by post-stress QGS was lower than that by rest QGS in patients with reversible defect and 10 (25%) of them showed decreases in EF more than 5% in post-stress QGS, as compared to that of rest QGS. Excellent correlations of EDVs, ESVs, EFs between rest and post-stress QGS were noted. Patients with fixed defect had higher correlation between defect can affect LVM measurement by QGS and patients with reversible defect shows post-stress LV dysfunction more frequently than patients with fixed perfusion defect

  7. Retos para los sistemas sanitarios de Latinoamérica: ¿qué puede aprenderse de la experiencia europea?

    Directory of Open Access Journals (Sweden)

    Figueras J

    2002-01-01

    Full Text Available Este artículo compara los retos de los sistemas sanitarios latinoamericanos y la experiencia en Europa. El marco conceptual se centra en cuatro funciones: a generar recursos; b producir intervenciones; c financiar, y d «ejercer rectoría». Es a este nivel donde los actores pueden influir sobre el desempeño del sistema. Se identifican cinco retos para Latinoamérica: a extender (prepago y solidaridad la protección financiera; b estabilizar en el tiempo dicha protección para épocas de crisis; c equilibrar los recursos coherentemente con la capacidad de financiar servicios, d aumentar la eficiencia ubicativa y técnica al producir servicios, y e mejorar la función de rectoría de las demás funciones en los sectores público y privado (el más difícil y más importante reto hoy para los sistemas latinoamericanos. Se analiza luego la experiencia de reforma en Europa, presentando: a experiencias sobre protección financiera en los sistemas tipo Beveridge y Bismarck; b estabilidad en tiempos de crisis refrendada recientemente (Oeste y con graves obstáculos (Este; c el esfuerzo por equilibrar camas hospitalarias y profesionales sanitarios combinando regulación e incentivos; d un aumento de la eficiencia en la producción de servicios priorizando más expresamente, dando voz a los pacientes, descentralizando la gestión y con incentivos de mercado, y e una mejora de la rectoría no regulando menos sino mejor (y en algunos casos, más. Tres áreas de la experiencia europea sobresalen: a combinar solidaridad con sostenibilidad financiera; b introducir mesuradamente incentivos de mercado pero manteniendo un claro papel rector del Estado, y c adoptar innovaciones en la organizacíon y producción de servicios. Pese a las dificultades metodológicas, la convergencia de los retos y las «soluciones» adoptadas justifica este análisis, pero las enseñanzas deben contemplarse desde cada contexto nacional. Un futuro artículo abordará las lecciones

  8. Simulation Study of PET System Using GATE%基于GATE的PET系统仿真研究

    Institute of Scientific and Technical Information of China (English)

    刘豪佳; 张斌

    2014-01-01

    PET and SPECT is the most advanced nuclear medical imaging technology .GATE is a dedicated Monte Carlo simulation platform for PET and SPECT .This study validates two GATE models of Simens ECAT EXACT HR+PET scanner and Simens PET/CT Biograph 2.After the simulation of PET systems completed , testing and performance evaluation of simulation systems were proceeded according to NEMA 2001 performance protocols , including spatial resolution , scatter fraction and sensitivity .Test results show that , performances of GATE simulation systems agree well with the experimental values .%PET和SPECT是现代核医学最高水平的影像技术,GATE是专用于PET和SPECT的蒙特卡罗仿真工具。研究以西门子公司的PET扫描仪 ECAT EXACT HR+和PET/CT Biograph2为原型,分别使用GATE实现其系统的完整仿真。依据NEMA 2001标准,对仿真系统的空间分辨率、散射分数和灵敏度分别进行测试与评估。测试结果表明,仿真系统性能参数和实验结果之间具有良好的一致性。

  9. La creación y promoción de experiencias en un destino turístico. Un análisis de la investigación y necesidades de actuación

    Directory of Open Access Journals (Sweden)

    Rita Carballo Fuentes

    2015-01-01

    Full Text Available El artículo realiza una profunda revisión teórica de un término de creciente interés: la experiencia. Se aborda la comprensión de las dimensiones de la experiencia turística, cómo analizarlas, y cómo desarrollar y comunicar una experiencia turística, presentado especial atención a la marca y los eventos como paradigma promocional de la misma. Como aportaciones principales, este trabajo analiza e identifica la situación de la investigación sobre experiencias turísticas, y finaliza con una propuesta: matriz de diseño de la experiencia, para la implementación práctica de experiencias en un destino.

  10. Dopamine transporter imaging with [123I]FP-CIT SPECT: potential effects of drugs

    International Nuclear Information System (INIS)

    Booij, Jan; Kemp, Paul

    2008-01-01

    [ 123 I]N-ω-fluoropropyl-2β-carbomethoxy-3β-{4-iodophenyl}nortropane ([ 123 I]FP-CIT) single photon emission computed tomography (SPECT) is a frequently and routinely used technique to detect or exclude dopaminergic degeneration by imaging the dopamine transporter (DAT) in parkinsonian and demented patients. This technique is also used in scientific studies in humans, as well as in preclinical studies to assess the availability of DAT binding in the striatum. In routine clinical studies, but also in scientific studies, patients are frequently on medication and sometimes even use drugs of abuse. Moreover, in preclinical studies, animals will be anesthetized. Prescribed drugs, drugs of abuse, and anesthetics may influence the visual interpretation and/or quantification of [ 123 I]FP-CIT SPECT scans. Here, we discuss the basic principle of how drugs and anesthetics might influence the visual interpretation and/or quantification of [ 123 I]FP-CIT SPECT scans. We also review drugs which are likely to have a significant influence on the visual interpretation and/or quantification of [ 123 I]FP-CIT SPECT scans. Additionally, we discuss the evidence as to whether frequently prescribed drugs in parkinsonian and demented patients may have an influence on the visual interpretation and/or quantification of [ 123 I]FP-CIT SPECT scans. Finally, we discuss our recommendations as to which drugs should be ideally withdrawn before performing a [ 123 I]FP-CIT SPECT scan for routine clinical purposes. The decision to withdraw any medication must always be made by the specialist in charge of the patient's care and taking into account the pros and cons of doing so. (orig.)

  11. ¿Los alumnos se aburren con la poesía?

    Directory of Open Access Journals (Sweden)

    José Coloma Maestre

    2012-08-01

    Full Text Available Con la pregunta del título de la experiencia, ¿los alumnos de E/LE se aburren con la poesía?, quiero reflexionar sobre qué motiva o no motiva realmente a nuestros alumnos cuando llevamos un texto a clase para trabajar con ellos. Veremos como para mí la actitud del profesor y las actividades que se generen a partir de ese texto serán fundamentales para conseguir el éxito y la atención de los alumnos.

  12. Experiencias docentes y su proyección en la identidad profesional: el caso de las maestras de Santa Marta y su entorno

    Directory of Open Access Journals (Sweden)

    María Concepción Domínguez Garrido

    2017-01-01

    Full Text Available Este artículo presenta los resultados de una investigación llevada a cabo en Santa Marta y el corregimiento de Juan y Medio-Riohacha (Colombia con un grupo de maestras afrodescendientes. El principal objetivo fue identificar las experiencias formativas que han marcado su estilo docente y las ha llevado a compartir una línea de desarrollo profesional, apoyada en el discurso narrativo y de implicación para dar respuesta a nuevos modelos de investigación y desarrollo profesional. A través de cuestionarios y entrevistas se recogieron las narrativas de 10 maestras, quienes respondieron a preguntas sobre sus experiencias formativas más significativas, teniendo en cuenta aspectos como: dónde, cuándo, por qué, para qué, con quién, qué, cómo, y sobre el impacto que ha tenido la experiencia docente en su desarrollo profesional. Se ha utilizado la metodología narrativa dado que el profesorado descubre en la identificación y análisis de las experiencias profesionales más innovadoras y relevantes que han vivido, las bases para aprender de su profesión y tomar decisiones para mejorar su identidad con ella. Los hallazgos derivados de esta investigación explicitan un camino de afianzamiento del pensamiento y actuaciones formativas, de las maestras implicadas, concretadas en: contextos escolares y familiares, finalidades para alcanzar el desarrollo profesional, desempeños en la práctica docente, escenarios de pluralidad y de encuentros de las culturas, así como en tiempos y cronología vivida.

  13. High diagnostic accuracy of low-dose gated-SPECT with solid-state ultrafast detectors: preliminary clinical results

    International Nuclear Information System (INIS)

    Gimelli, Alessia; Genovesi, Dario; Giorgetti, Assuero; Marzullo, Paolo; Bottai, Matteo; Di Martino, Fabio

    2012-01-01

    Appropriate use of SPECT imaging is regulated by evidence-based guidelines and appropriateness criteria in an effort to limit the burden of radiation administered to patients. We aimed at establishing whether the use of a low dose for stress-rest single-day nuclear myocardial perfusion imaging on an ultrafast (UF) cardiac gamma camera using cadmium-zinc-telluride solid-state detectors could be used routinely with the same accuracy obtained with standard doses and conventional cameras. To this purpose, 137 consecutive patients (mean age 61 ± 8 years) with known or suspected coronary artery disease (CAD) were enrolled. They underwent single-day low-dose stress-rest myocardial perfusion imaging using UF SPECT and invasive coronary angiography. Patients underwent the first scan with a 7-min acquisition time 10 min after the end of the stress protocol (dose range 185 to 222 MBq of 99m Tc-tetrofosmin). The rest scan (dose range 370 to 444 MBq of 99m Tc-tetrofosmin) was acquired with a 6-min acquisition time. The mean summed stress scores (SSS) and mean summed rest scores (SRS) were obtained semiquantitatively. Coronary angiograms showed significant epicardial CAD in 83% of patients. Mean SSS and SRS were 10 ± 5 and 3 ± 3, respectively. Overall the area under the ROC curve for the SSS values was 0.904, while the areas under the ROC curves for each vascular territory were 0.982 for the left anterior descending artery, 0.931 for the left circumflex artery and 0.889 for the right coronary artery. This pilot study demonstrated the feasibility of a low-dose single-day stress-rest fasting protocol performed using UF SPECT, with good sensitivity and specificity in detecting CAD at low patient exposure, opening new perspectives in the use of myocardial perfusion in ischaemic patients. (orig.)

  14. High diagnostic accuracy of low-dose gated-SPECT with solid-state ultrafast detectors: preliminary clinical results

    Energy Technology Data Exchange (ETDEWEB)

    Gimelli, Alessia; Genovesi, Dario; Giorgetti, Assuero; Marzullo, Paolo [CNR, Fondazione Toscana Gabriele Monasterio, Pisa (Italy); Bottai, Matteo [University of South Carolina, Division of Biostatistics, Columbia, SC (United States); Karolinska Institutet, Division of Biostatistics, Stockholm (Sweden); Di Martino, Fabio [AOUP, UO Fisica Sanitaria, Pisa (Italy)

    2012-01-15

    Appropriate use of SPECT imaging is regulated by evidence-based guidelines and appropriateness criteria in an effort to limit the burden of radiation administered to patients. We aimed at establishing whether the use of a low dose for stress-rest single-day nuclear myocardial perfusion imaging on an ultrafast (UF) cardiac gamma camera using cadmium-zinc-telluride solid-state detectors could be used routinely with the same accuracy obtained with standard doses and conventional cameras. To this purpose, 137 consecutive patients (mean age 61 {+-} 8 years) with known or suspected coronary artery disease (CAD) were enrolled. They underwent single-day low-dose stress-rest myocardial perfusion imaging using UF SPECT and invasive coronary angiography. Patients underwent the first scan with a 7-min acquisition time 10 min after the end of the stress protocol (dose range 185 to 222 MBq of {sup 99m}Tc-tetrofosmin). The rest scan (dose range 370 to 444 MBq of {sup 99m}Tc-tetrofosmin) was acquired with a 6-min acquisition time. The mean summed stress scores (SSS) and mean summed rest scores (SRS) were obtained semiquantitatively. Coronary angiograms showed significant epicardial CAD in 83% of patients. Mean SSS and SRS were 10 {+-} 5 and 3 {+-} 3, respectively. Overall the area under the ROC curve for the SSS values was 0.904, while the areas under the ROC curves for each vascular territory were 0.982 for the left anterior descending artery, 0.931 for the left circumflex artery and 0.889 for the right coronary artery. This pilot study demonstrated the feasibility of a low-dose single-day stress-rest fasting protocol performed using UF SPECT, with good sensitivity and specificity in detecting CAD at low patient exposure, opening new perspectives in the use of myocardial perfusion in ischaemic patients. (orig.)

  15. Tomografía cerebral, SPECT cerebral y neurocognición en trauma craneoencefálico

    OpenAIRE

    Casallo Quiliano, Carlos

    2013-01-01

    Introduccion: La tomografía cerebral (TC) es el examen de elección para evaluar un trauma cráneo encefálico (TCE) agudo. Otras pruebas, como la tomografía computarizada por emisión de fotón único (SPECT) están siendo utilizadas en el TCE, siendo mejor que la TC o la Resonancia magnética (RM) en la evaluación funcional del cerebro. La mayoría de estudios no incluyen, ni relacionan los resultados de la TC y SPECT con la evaluación neuropsicológica, la cual puede estar alterada a pesar de tener ...

  16. Parallel Implementation of the Multi-Dimensional Spectral Code SPECT3D on large 3D grids.

    Science.gov (United States)

    Golovkin, Igor E.; Macfarlane, Joseph J.; Woodruff, Pamela R.; Pereyra, Nicolas A.

    2006-10-01

    The multi-dimensional collisional-radiative, spectral analysis code SPECT3D can be used to study radiation from complex plasmas. SPECT3D can generate instantaneous and time-gated images and spectra, space-resolved and streaked spectra, which makes it a valuable tool for post-processing hydrodynamics calculations and direct comparison between simulations and experimental data. On large three dimensional grids, transporting radiation along lines of sight (LOS) requires substantial memory and CPU resources. Currently, the parallel option in SPECT3D is based on parallelization over photon frequencies and allows for a nearly linear speed-up for a variety of problems. In addition, we are introducing a new parallel mechanism that will greatly reduce memory requirements. In the new implementation, spatial domain decomposition will be utilized allowing transport along a LOS to be performed only on the mesh cells the LOS crosses. The ability to operate on a fraction of the grid is crucial for post-processing the results of large-scale three-dimensional hydrodynamics simulations. We will present a parallel implementation of the code and provide a scalability study performed on a Linux cluster.

  17. Evaluating low pass filters on SPECT reconstructed cardiac orientation estimation

    Science.gov (United States)

    Dwivedi, Shekhar

    2009-02-01

    Low pass filters can affect the quality of clinical SPECT images by smoothing. Appropriate filter and parameter selection leads to optimum smoothing that leads to a better quantification followed by correct diagnosis and accurate interpretation by the physician. This study aims at evaluating the low pass filters on SPECT reconstruction algorithms. Criteria for evaluating the filters are estimating the SPECT reconstructed cardiac azimuth and elevation angle. Low pass filters studied are butterworth, gaussian, hamming, hanning and parzen. Experiments are conducted using three reconstruction algorithms, FBP (filtered back projection), MLEM (maximum likelihood expectation maximization) and OSEM (ordered subsets expectation maximization), on four gated cardiac patient projections (two patients with stress and rest projections). Each filter is applied with varying cutoff and order for each reconstruction algorithm (only butterworth used for MLEM and OSEM). The azimuth and elevation angles are calculated from the reconstructed volume and the variation observed in the angles with varying filter parameters is reported. Our results demonstrate that behavior of hamming, hanning and parzen filter (used with FBP) with varying cutoff is similar for all the datasets. Butterworth filter (cutoff > 0.4) behaves in a similar fashion for all the datasets using all the algorithms whereas with OSEM for a cutoff < 0.4, it fails to generate cardiac orientation due to oversmoothing, and gives an unstable response with FBP and MLEM. This study on evaluating effect of low pass filter cutoff and order on cardiac orientation using three different reconstruction algorithms provides an interesting insight into optimal selection of filter parameters.

  18. Validation of use of the low energies library in the GATE program: assessment of the effective mass attenuation coefficient

    International Nuclear Information System (INIS)

    Argenta, Jackson; Brambilla, Claudia R.; Silva, Ana Maria Marques da; Hoff, Gabriela

    2010-01-01

    Geant4 Application for Emission Tomography program (GATE) is a versatile toolkit for nuclear medicine simulations of SPECT and PET studies. GATE takes advantage of well-validated libraries of physics processes models, geometry description, tracking of particles through materials, response of detector and visualization tools offered by Geant4 (version 4.0). One package available to simulate electromagnetic interactions is low energy electromagnetic processes (LEP). The purpose of this work was to evaluate the LEP package used by GATE 4 for nuclear medicine shielding simulations. Several simulations were made involving a monodirectional and 140 keV monoenergetic point source beam, passing through barriers of variable thickness of water and lead. The results showed good agreement with the theoretical model, indicating that GATE 4 uses correctly the LEP package. (author)

  19. Influencia del microsite en la imagen de marca a través de experiencias significativas

    Directory of Open Access Journals (Sweden)

    Belinda de Frutos Torres

    2012-04-01

    Full Text Available Las empresas e instituciones, actualmente, son conscientes del potencial que ofrece internet como instrumento para mantener una relación activa con sus públicos de interés. Con este propósito diseñan estrategias de comunicación específicamente destinadas a que el usuario pueda establecer una relación interactiva con la marca. Una de las formas de estar presente en la red es a través del microsite que se perfilan como una solución para estrechar los lazos entre el usuario y la marca.El objetivo del estudio es valorar la influencia del microsite como herramienta de comunicación corporativa y su importancia en la construcción de la imagen de marca. Para ello se ha llevado a cabo un estudio empírico a partir de tres acciones de comunicación reales de tres marcas conocidas representativas de tres estrategias de comunicación. Las tres acciones se llevaron a cabo con microsites y fueron visitados y evaluados por una muestra de 41 personas. Los resultados muestran que la valoración global hacia el microsite puede explicarse en torno a tres dimensiones su grado de entretenimiento, su valor informativo y el agrado asociado. Se comprueba que la experiencia generada por el microsite es diferente dependiendo de la estrategia de comunicación utilizada y contribuye de forma distinta a explicar la actitud hacia la marca. Cada estrategia constituye una experiencia diferenciada para el usuario sin embargo la implicación del usuario con la categoría del producto obtiene un papel determinante en  la relación con la imagen de marca.

  20. La influencia del consumo simbólico en la intensidad de uso de las redes sociales digitales y el valor percibido de las experiencias

    Directory of Open Access Journals (Sweden)

    Gonzalo Luna Cortés

    2017-03-01

    Full Text Available Esta investigación analiza cómo el consumo simbólico (congruencia entre el objeto consumido y la identidad del consumidor se extiende en la actualidad hasta el consumo de experiencias. Como muestran los resultados, cuando un consumidor observa que una experiencia refuerza su identidad, este percibe mayor valor de dicha experiencia, lo que aumenta su satisfacción y su intención de recompra. También se desprende de los resultados que, a la hora de materializar la experiencia de cara al exterior, los consumidores hacen uso de una herramienta fundamental: las redes sociales digitales. Así, los resultados de la investigación muestran que los consumidores utilizan más las redes sociales cuando realizan consumo de experiencias congruentes con su identidad, y ello aumenta aún más el valor de la experiencia. Finalmente, y como parte de las conclusiones, se incluyen unas directrices a nivel gerencial que se basan en los resultados de la investigación.

  1. SPECT/CT and pulmonary embolism

    Energy Technology Data Exchange (ETDEWEB)

    Mortensen, Jann [Copenhagen University Hospital, Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen (Denmark); The Faroese National Hospital, Department of Medicine, Torshavn (Faroe Islands); Gutte, Henrik [Copenhagen University Hospital, Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen (Denmark); Herlev Hospital, Copenhagen University Hospital, Department of Radiology, Copenhagen (Denmark); University of Copenhagen, Cluster for Molecular Imaging, Faculty of Health Sciences, Copenhagen (Denmark)

    2014-05-15

    Acute pulmonary embolism (PE) is diagnosed either by ventilation/perfusion (V/P) scintigraphy or pulmonary CT angiography (CTPA). In recent years both techniques have improved. Many nuclear medicine centres have adopted the single photon emission CT (SPECT) technique as opposed to the planar technique for diagnosing PE. SPECT has been shown to have fewer indeterminate results and a higher diagnostic value. The latest improvement is the combination of a low-dose CT scan with a V/P SPECT scan in a hybrid tomograph. In a study comparing CTPA, planar scintigraphy and SPECT alone, SPECT/CT had the best diagnostic accuracy for PE. In addition, recent developments in the CTPA technique have made it possible to image the pulmonary arteries of the lungs in one breath-hold. This development is based on the change from a single-detector to multidetector CT technology with an increase in volume coverage per rotation and faster rotation. Furthermore, the dual energy CT technique is a promising modality that can provide functional imaging in combination with anatomical information. Newer high-end CT scanners and SPECT systems are able to visualize smaller subsegmental emboli. However, consensus is lacking regarding the clinical impact and treatment. In the present review, SPECT and SPECT in combination with low-dose CT, CTPA and dual energy CT are discussed in the context of diagnosing PE. (orig.)

  2. El Papel de la Cualidad del Servicio y de la Imagen de la Tienda em la Experiencia de Consumo de Servicios Automotrices.

    Directory of Open Access Journals (Sweden)

    Ieda Pedógia Martins Damian

    2014-06-01

    Full Text Available Los servicios han desempeñado un papel cada vez más relevante, al agregar valor a los consumidores. En ese sentido, la evaluación de la experiencia de consumo en relación a esos servicios es importante para los minoristas que actúan en ambientes competitivos. El objetivo de este trabajo es analizar el papel de la cualidad del servicio y de la imagen de la tienda en la experiencia de consumo de servicios automotrices. El estudio fue dividido en dos momentos. En el primero se realizó una investigación cuantitativa (survey con 1346 consumidores, con el objetivo de obtener de ellos una evaluación de los atributos de imagen y cualidad y su contribución para una evaluación positiva de la experiencia de consumo. En seguida, fue realizada una investigación cualitativa, del tipo grupo enfocado, para discutir los resultados obtenidos en la investigación cuantitativa. La principal contribución del estudio fue dejar evidente la relevancia de los aspectos relacionados a la imagen del prestador del servicio. Se debe destacar que la imagen presentó, en la investigación, un papel tan relevante cuanto el de los elementos directamente relacionados a la cualidad de los servicios para el desarrollo de una experiencia de consumo agradable.

  3. Use of the GATE Monte Carlo package for dosimetry applications

    Energy Technology Data Exchange (ETDEWEB)

    Visvikis, D. [INSERM U650, LaTIM, University Hospital Medical School, F 29609 Brest (France)]. E-mail: Visvikis.Dimitris@univ-brest.fr; Bardies, M. [INSERM U601, CHU Nantes, F 44093 Nantes (France); Chiavassa, S. [INSERM U601, CHU Nantes, F 44093 Nantes (France); Danford, C. [Department of Medical Physics, MSKCC, New York (United States); Kirov, A. [Department of Medical Physics, MSKCC, New York (United States); Lamare, F. [INSERM U650, LaTIM, University Hospital Medical School, F 29609 Brest (France); Maigne, L. [Departement de Curietherapie-Radiotherapie, Centre Jean Perrin, F 63000 Clemont-Ferrand (France); Staelens, S. [UGent-ELIS, St-Pietersnieuwstraat, 41, B 9000 Gent (Belgium); Taschereau, R. [CRUMP Institute for Molecular Imaging, UCLA, Los Angeles (United States)

    2006-12-20

    One of the roles for Monte Carlo (MC) simulation studies is in the area of dosimetry. A number of different codes dedicated to dosimetry applications are available and widely used today, such as MCNP, EGSnrc and PTRAN. However, such codes do not easily facilitate the description of complicated 3D sources or emission tomography systems and associated data flow, which may be useful in different dosimetry application domains. Such problems can be overcome by the use of specific MC codes such as GATE (GEANT4 Application to Tomographic Emission), which is based on Geant4 libraries, providing a scripting interface with a number of advantages for the simulation of SPECT and PET systems. Despite this potential, its major disadvantage is in terms of efficiency involving long execution times for applications such as dosimetry. The strong points and disadvantages of GATE in comparison to other dosimetry specific codes are discussed and illustrated in terms of accuracy, efficiency and flexibility. A number of features, such as the use of voxelised and moving sources, as well as developments such as advanced visualization tools and the development of dose estimation maps allowing GATE to be used for dosimetry applications are presented. In addition, different examples from dosimetry applications with GATE are given. Finally, future directions with respect to the use of GATE for dosimetry applications are outlined.

  4. Una experiencia de campo con una cooperativa de promotores ambientales

    OpenAIRE

    Bazán, Claudia I.; Ferrari, Liliana

    2014-01-01

    La presente ponencia describe el trabajo que se está realizando con una cooperativa de promotores ambientes, El CorreCamino, cuya propuesta no es pensada como una actividad marginal sino que toma el proceso de reciclado como contribución social y enfatiza el papel activo del trabajador en solidaridad con los vecinos y el espacio ambiental. La metodología utilizada es la Investigación Acción Participativa (IAP) cuyo principal objetivo es aunar los ...

  5. Prácticas de enseñanza para el logro de competencias. Resultados de una experiencia didáctica apoyada en Moodle

    Directory of Open Access Journals (Sweden)

    Sosa, Mabel

    2009-01-01

    Full Text Available Los cambios propiciados por las TIC, afectan directamente a la función que las universidades cumplen en la sociedad y ponen de manifiesto la necesidad de revisar sus referentes actuales y promover experiencias innovadoras en el proceso educativo. Así, la innovación, está relacionada con perspectivas de globalidad e implica cambios en el currículo, en las formas de ver, pensar, organizar y vincular el proceso educativo. La aplicación de las TIC en acciones de formación bajo la concepción de enseñanza flexible presenta diferentes posibilidades de cambio y renovación educativa. En este sentido, la propuesta de este trabajo consiste en el diseño de prácticas de enseñanza orientadas al logro de competencias de orden superior, apoyadas en Moodle. La experiencia didáctica es llevada a cabo en la asignatura Arquitectura del Computador en la Universidad Nacional de Santiago del Estero. Se presentan los resultados obtenidos en la experiencia, relacionados con el desempeño académico de los estudiantes, según la valoración del profesor; la actitud, motivación y satisfacción de los estudiantes con respecto a la modalidad de enseñanza propuesta y la calidad educativa de la herramienta como complemento de la modalidad presencial que incluye distintas tecnologías de comunicación con fines educativos. Los resultados obtenidos animan a continuar trabajando en esta línea promoviendo nuevas formas de aprender y construir el conocimiento.

  6. Disneyzación, parques temáticos y cultura corporativa en el capitalismo terciario: experiencias Xcaret, Riviera Maya (México)

    OpenAIRE

    Khafash Echevarría, Leila

    2016-01-01

    Esta tesis se propuso desde la perspectiva de la geografía y la antropología demostrar la disneyzación patrimonial recreada, tomando un modelo de negocio corporativo de parques temáticos en pleno auge turístico de la Riviera Maya en México y su hinterland (Experiencias Xcaret), corporativo de parques temáticos. Se propuso igualmente demostrar la expansión de los parques, y algunos efectos territoriales en el contexto de la economía de las experiencias emocionales. Con este objetivo general se...

  7. La experiencia emocional de la sexualidad: una perspectiva psicofisiológica

    Directory of Open Access Journals (Sweden)

    Mas, Manuel

    1999-05-01

    Full Text Available Not available.Este ensayo presenta unas reflexiones sobre la experiencia emocional y las bases psicofisiológicas del comportamiento sexual. Se discuten las dificultades conceptuales y metodológicas que ofrece el estudio científico de la sexualidad y el modo en que las afrontan sus investigadores. Se describen los principales correlatos neurobiológicos y endocrinos del comportamiento sexual obtenidos en animales de experimentación y en humanos, con énfasis en las peculiaridades que presenta el orden de los primates, especialmente los antropoides, con respecto a las demás especies en lo que respecta a su fisiología sexual. Se comentan los riesgos de basar reglas morales en observaciones conductuales erróneas.

  8. Análisis de la experiencia del usuario en la ciudad posmoderna desde la ergonomía, lo sustentable y lo simbólico : Estudio de caso: Santa Fe, México

    OpenAIRE

    Solano Meneses, Eska Elena; Mercado Colín, Lucila; Rodea Chávez, Alejandro

    2014-01-01

    El presente estudio hace énfasis en el cambio de paradigma del diseño hacia las posturas de diseño centradas en el usuario (ergonomía y accesibilidad), refiriéndose específicamente a la experiencia simbólica que el individuo vive en la ciudad posmoderna. Dicha experiencia simbólica ha de ser vista desde la relación del individuo con el entorno (el diseño ecológicamente sustentable) y con el reconocimiento de sus capacidades y limitaciones (el diseño socialmente sustentable). El concepto...

  9. Serial SPECT in children with partial epilepsy

    International Nuclear Information System (INIS)

    Hosoya, Machiko; Ushiku, Hideo

    1995-01-01

    We performed serial single-photon emission CT (SPECT) with N-isopropyl-p-( 123 I)-Iodoamphetamine to measure the regional cerebral blood flow (rCBF) in 15 children with partial epilepsy. SPECT showed focal changes in 14 cases. Ten cases had abnormalities in the initial SPECT and another four cases in the second test. The cases with normal rCBF in initial SPECT had been tested in an early phase after the onset, and then decreased rCBF were observed in the second SPECT. The cases with both abnormal rCBF in the initial SPECT and improved rCBF in the second SPECT showed good prognosis in clinico-electrophysiological evolutions. In cases with abnormal changes of rCBF in the second SPECT, clinical prognosis was found to be not so good. These findings suggest that serial SPECT may be used to follow the course of epilepsy. (author)

  10. Efficacy of SPECT over planar bone scan in the diagnosis of solitary vertebral lesions in patients with low back pain

    International Nuclear Information System (INIS)

    Sudhakar, Pushpalatha; Bhushan, Shanti M.; Ranadhir, G.; Prabhakar Rao, V.V.S.; Sharma, Anshu Rajnish; Narsimuhulu, G.

    2010-01-01

    The purpose of our study has been to evaluate the efficacy of single photon emission computed tomography (SPECT) over planar bone scan in identifying solitary vertebral lesions in patients with low backache and its ability to differentiate various pathologies according to the uptake pattern. Materials and Methods: The study included twenty patients out of whom six patients presented with known carcinoma and fourteen patients with low back pain. SPECT was done in all following planar skeletal survey. Benign and malignant lesions were identified according to the uptake pattern in vertebral elements, based on Gary F. Gates observations. Final diagnosis was obtained by means of biopsy or correlation with radiograph or computed tomography (CT) or magnetic resonance imaging (MRI), and/or follow up. Results: SPECT detected additional 30% of solitary vertebral lesions that were obscured on planar scan. Seven out of twenty were localized in anterior vertebral body and were diagnosed as benign ostophytes in six and osteoma in one substantiating the previous observations. Out of six cases of known carcinoma, three were having solitary metastases and showed posterior vertebral body uptake with pedicle involvement. SPECT could localize specific lesions as source of pain in eleven patients with low back pain (78%) and identified various etiologies including benign tumors (osteoid osteoma and osteoma), facet arthritis, discitis, transverse process fractures and spondylolysis. Conclusion: Our study highlighted the higher diagnostic value of SPECT over planar skeletal scintigraphy in localizing solitary vertebral lesions in low backache patients. Based on SPECT pattern, malignant and benign lesions could be differentiated in the given clinical context. (author)

  11. Ejection fraction in myocardial perfusion imaging assessed with a dynamic phantom: comparison between IQ-SPECT and LEHR.

    Science.gov (United States)

    Hippeläinen, Eero; Mäkelä, Teemu; Kaasalainen, Touko; Kaleva, Erna

    2017-12-01

    Developments in single photon emission tomography instrumentation and reconstruction methods present a potential for decreasing acquisition times. One of such recent options for myocardial perfusion imaging (MPI) is IQ-SPECT. This study was motivated by the inconsistency in the reported ejection fraction (EF) and left ventricular (LV) volume results between IQ-SPECT and more conventional low-energy high-resolution (LEHR) collimation protocols. IQ-SPECT and LEHR quantitative results were compared while the equivalent number of iterations (EI) was varied. The end-diastolic (EDV) and end-systolic volumes (ESV) and the derived EF values were investigated. A dynamic heart phantom was used to produce repeatable ESVs, EDVs and EFs. Phantom performance was verified by comparing the set EF values to those measured from a gated multi-slice X-ray computed tomography (CT) scan (EF True ). The phantom with an EF setting of 45, 55, 65 and 70% was imaged with both IQ-SPECT and LEHR protocols. The data were reconstructed with different EI, and two commonly used clinical myocardium delineation software were used to evaluate the LV volumes. The CT verification showed that the phantom EF settings were repeatable and accurate with the EF True being within 1% point from the manufacture's nominal value. Depending on EI both MPI protocols can be made to produce correct EF estimates, but IQ-SPECT protocol produced on average 41 and 42% smaller EDV and ESV when compared to the phantom's volumes, while LEHR protocol underestimated volumes by 24 and 21%, respectively. The volume results were largely similar between the delineation methods used. The reconstruction parameters can greatly affect the volume estimates obtained from perfusion studies. IQ-SPECT produces systematically smaller LV volumes than the conventional LEHR MPI protocol. The volume estimates are also software dependent.

  12. Educación para el empoderamiento: Experiencias con mujeres rurales costarricenses

    Directory of Open Access Journals (Sweden)

    Lili Quesada-Saravia

    2002-12-01

    Full Text Available Debido a la exclusión social que se vive de manera diferenciada en el interior de la población femenina de las zonas rurales, el Programa Género y democracia del CEP-ALFORJA trabaja con mujeres de la zona Norte del país con el propósito de poner en práctica la estrategia del empoderamiento con el fin de lograr poder en la toma de decisiones, conocimiento de uno mismo, sentido de seguridad y visión futura y autonomía para resolver necesidades y actuar en la esfera pública.

  13. Experiencias encarnadas. Representaciones audiovisuales de madre(s) y maternidad(es)

    OpenAIRE

    Brigidi, Serena

    2014-01-01

    [ES] El artículo presenta una reflexión encarnada sobre la experiencia de ser madre y las representaciones de la maternidad en la cultura occidental, en anuncios y series televisivas, documentales y películas. Habitualmente, la maternidad es imaginada como el producto (tener un hijo, convertirse en madre) y no como el arduo proceso que representa a lo largo de la vida de una persona. Se opta por presentarla con un carácter universal y se usa como una estrategia cinematográfica cua...

  14. Literatura infantil para no lectores. Una experiencia desde la universidad

    OpenAIRE

    Ponce Naranjo, Genoveva

    2016-01-01

    La lectura es un tema de indiscutible importancia, como lo refiere Michèle Petit (1999, p. 19), “la lectura es tanto un medio para elaborar su subjetividad como un medio para acceder al conocimiento”; por eso, la experiencia académica con estudiantes de la Carrera de Ciencias Sociales de la Facultad de Ciencias de la Educación de la Universidad Nacional de Chimborazo,  tuvo como objetivo, resignificar  la lectura como práctica cotidiana, a través de una metodología cualitativa que apoyada en ...

  15. Clinical applications of SPECT-CT

    Energy Technology Data Exchange (ETDEWEB)

    Ahmadzadehfar, Hojjat; Biersack, Hans-Juergen (eds.) [University Hospital Bonn (Germany). Dept. of Nuclear Medicine

    2014-06-01

    Covers the full spectrum of clinical applications of SPECT/CT in diagnosis of benign and malignant diseases. Includes chapters on the use of SPECT/CT for dosimetry and for therapy planning. Completely up to date. Many helpful illustrations. SPECT/CT cameras have considerably improved diagnostic accuracy in recent years. Such cameras allow direct correlation of anatomic and functional information, resulting in better localization and definition of scintigraphic findings. In addition to this anatomic referencing, CT coregistration provides superior quantification of radiotracer uptake based on the attenuation correction capabilities of CT. Useful applications of SPECT/CT have been identified not only in oncology but also in other specialties such as orthopedics and cardiology. This book covers the full spectrum of clinical applications of SPECT/CT in diagnosis and therapy planning of benign and malignant diseases. Opening chapters discuss the technology and physics of SPECT/CT and its use for dosimetry. The role of SPECT/CT in the imaging of a range of pathologic conditions is then addressed in detail. Applications covered include, among others, imaging of the thyroid, bone, and lungs, imaging of neuroendocrine tumors, cardiac scintigraphy, and sentinel node scintigraphy. Individual chapters are also devoted to therapy planning in selective internal radiation therapy of liver tumors and bremsstrahlung SPECT/CT. Readers will find this book to be an essential and up-to-date source of information on this invaluable hybrid imaging technique.

  16. El aprendizaje de la traducción a través del uso de portfolios: descripción de una experiencia

    Directory of Open Access Journals (Sweden)

    Francisco Javier Fernández Polo

    2011-12-01

    Full Text Available El aprendizaje de la traducción a través del uso de portfolios: descripción de una experienciaEn este trabajo se describe una experiencia pedagógica consistente en la introducción del portafolio como herramienta de aprendizaje y evaluación en un curso universitario de traducción. La descripción se basa en datos recogidos durante dos años y en los resultados de un cuestionario administrado a los participantes. Tras una breve contextualización de la experiencia y la reflexión sobre los aspectos más relevantes del portafolio para la enseñanza de la traducción, específicamente en la universidad, se ofrece una descripción exhaustiva de los efectos positivos de la utilización del instrumento en el curso. El trabajo termina con una valoración de la experiencia por parte de los participantes. 

  17. SPECT in psychiatry

    International Nuclear Information System (INIS)

    Barocka, A.; Feistel, H.; Ebert, D.; Lungershausen, E.

    1993-01-01

    This review presents Single Photon Emission Computed Tomography (SPECT) as a powerful tool for clinical use and research in psychiatry. Its focus is on regional cerebral blood flow, measured with technetium labelled HMPAO. In addition, first results with brain receptor imaging, concerning dopamin-D 2 and benzodiazepine receptors, are covered. Due to major improvements in image quality, and impressive number of results has been accumulated in the past three years. The authors caution against using SPECT results as markers for disease entities. A finding like 'hypofrontality' is considered typical of a variety of mental disorders. Clearly both, more experience with SPECT and contributions from psychopathology, are needed. (orig.) [de

  18. Brain SPECT in children

    International Nuclear Information System (INIS)

    Guyot, M.; Baulieu, J.L.

    1996-01-01

    Brain SPECT in child involves specific trends regarding the patient cooperation, irradiation, resolution and especially interpretation because of the rapid scintigraphic modifications related to the brain maturation. In a general nuclear medicine department, child brain SPECT represents about 2 % of the activity. The choice indications are the perfusion children: thallium and MIBI in brain tumours, pharmacological and neuropsychological interventions. In the future, brain dedicated detectors and new radiopharmaceuticals will promote the development of brain SPECT in children. (author)

  19. Performance evaluation of D-SPECT: a novel SPECT system for nuclear cardiology

    Science.gov (United States)

    Erlandsson, Kjell; Kacperski, Krzysztof; van Gramberg, Dean; Hutton, Brian F.

    2009-05-01

    D-SPECT (Spectrum Dynamics, Israel) is a novel SPECT system for cardiac perfusion studies. Based on CZT detectors, region-centric scanning, high-sensitivity collimators and resolution recovery, it offers potential advantages over conventional systems. A series of measurements were made on a β-version D-SPECT system in order to evaluate its performance in terms of energy resolution, scatter fraction, sensitivity, count rate capability and resolution. Corresponding measurements were also done on a conventional SPECT system (CS) for comparison. The energy resolution of the D-SPECT system at 140 keV was 5.5% (CS: 9.25%), the scatter fraction 30% (CS: 34%), the planar sensitivity 398 s-1 MBq-1 per head (99mTc, 10 cm) (CS: 72 s-1 MBq-1), and the tomographic sensitivity in the heart region was in the range 647-1107 s-1 MBq-1 (CS: 141 s-1 MBq-1). The count rate increased linearly with increasing activity up to 1.44 M s-1. The intrinsic resolution was equal to the pixel size, 2.46 mm (CS: 3.8 mm). The average reconstructed resolution using the standard clinical filter was 12.5 mm (CS: 13.7 mm). The D-SPECT has superior sensitivity to that of a conventional system with similar spatial resolution. It also has excellent energy resolution and count rate characteristics, which should prove useful in dynamic and dual radionuclide studies.

  20. El trabajo colegiado, un espacio para narrar las experiencias desde la práctica docente

    Directory of Open Access Journals (Sweden)

    Maríadel Rosario Landín Miranda

    2016-01-01

    Full Text Available Gestionar el aprendizaje y reaprendizaje durante el profesorado es todo un reto y todo un campo de estudio, por ello, en este trabajo, presentamos nuestra experiencia en la implementación de un proyecto de intervención que tuvo como propósito principal, generar un espacio colegiado para el aprendizaje de las experiencias docentes. El proyecto se implementó en la Escuela Secundaria Artículo 3° de Poza Rica, Veracruz, México, durante el periodo de agosto de 2014 a julio de 2015. La metodología base usada para el desarrollo del proyecto, fue la metodología APRA (Acceso, Permanencia y Rendimiento Académico, que es una propuesta de intervención que considera los elementos fundamentales que apoyan los procesos sistemáticos de cambio y mejora institucional. La estrategia de trabajo transversal empleada durante la intervención fue la narrativa, apoyada de otras estrategias, como el cuaderno docente, la narración de experiencias docentes, el trabajo colegiado con retroalimentación grupal y la autoevaluación.

  1. Brain SPECT in childhood

    International Nuclear Information System (INIS)

    Tranquart, F.; Saliba, E.; Prunier, C.; Baulieu, F.; Besnard, J.C.; Guilloteau, D.; Baulieu, J.L.

    2001-01-01

    The modalities and the indications of perfusion and neurotransmission SPECT in childhood are presented. The perfusion as well as neurotransmission tracers have not yet authorization for use in children; they have to be used by prescription of magistral preparation or in research protocols. The radioprotection rules have to be strictly respected. The most frequent indication of perfusion SPECT is pharmacologically resistant epilepsy; the ictal SPECT before surgery allows the localization of the epileptogenic focus. Other indications are relevant in the prognosis of neonatal anoxia and encephalitis. In psychiatric disorders, especially in autism, the interest is the physiopathological approach of the brain dysfunctions. The neurotransmission SPECT is emerging as a consequence of the development of new radiotracer, as the dopaminergic system ligands. The decrease of the dopamine D2 receptors in the striatum can be imaged and quantified in the neonate. The lesions of dopamine system seem to be a consequence of the neonatal hypoxia-ischemia and it is predictive of motor sequelae. Brain SPECT should become a routine examination in child neurologic and psychiatric disorders. (authors)

  2. Leer sobre la muerte en la Biblioteca de Aula: una experiencia práctica de lectura en un aula de Educación Infantil

    Directory of Open Access Journals (Sweden)

    Moisés Selfa Sastre

    2015-01-01

    Full Text Available Este artículo muestra una experiencia de lectura sobre el tema de la muerte en un aula de 3º de Educación Infantil con uno de los cuentos que forman parte de la Biblioteca de Aula de este nivel educativo. La lectura de este texto narrativo se organiza en seis sesiones en las que a partir de un plan de diálogo se pretende trabajar la comprensión literal del texto y la interpretación de este. Las diversas producciones en forma de dibujos ilustrados con la escritura de palabras demuestran que la experiencia fue del todo positiva y que se alcanzó el objetivo inicial de la lectura y comprensión del texto narrativo escogido.

  3. LO QUE EL OJO NO VE: ANÁLISIS DE UNA EXPERIENCIA

    Directory of Open Access Journals (Sweden)

    J.A. García-García

    2010-09-01

    Full Text Available Durante diez meses hemos realizado una actividad-exposición en el Parque de las Ciencias de Granada. En el espacio “Ventana a la Ciencia” la exposición “Lo que el ojo no ve” ha pretendido mostrar a la ciudadanía aspectos de la Óptica relacionados conlos límites de la visión humana y los avances científicos que han permitido superar dichos límites. Ha sido una actividad didáctica, divulgativa e interactiva, que ha buscado fomentar la reflexión del visitante.El objetivo fundamental de este trabajo es analizar dicha experiencia, planteándonos si experiencias como ésta contribuyen a fomentar la cultura científica de la ciudadanía. Para realizar la evaluación de la misma se ha aplicado una encuesta a una muestra de los visitantes cuyos resultados muestran que más del 90% consideraque ha aprendido de ella, al tiempo que la valoran como divertida. Así mismo, al pedírseles que la calificaran, lo han hecho con una nota media de 9 sobre 10. Por la experiencia vivida y por los resultados obtenidos, consideramos que actividades como ésta resultan de interés y debieran potenciarse como una vía válida para la divulgación científica.

  4. Formación en competencias de futuros Contadores Públicos: Una experiencia docente en el ámbito internacional

    Directory of Open Access Journals (Sweden)

    Javier Montoya del Corte

    2013-01-01

    Full Text Available Este trabajo describe el planteamiento, desarrollo y resultados de una experiencia docente para la formación en competencias de estudiantes universitarios de Contaduría Pública (CP de España y México. En concreto, se trató de fortalecer algunas habilidades profesionales requeridas en las International Education Standards (IES de la International Federation of Accountants (IFAC. Como prácticas docentes se utilizó el estudio de casos, lecturas y vídeos, discusión plenaria en el aula a través de videoconferencia y aprendizaje colaborativo en pequeños grupos. Los hallazgos obtenidos son indicativos de la efectividad de este tipo de experiencias docentes para el desarrollo de ciertas habilidades profesionales. Además, los estudiantes que trabajaron en equipos internacionales desarrollaron en mayor medida algunas habilidades relacionadas con la interculturalidad, como interactuar con personas de diferentes culturas, trabajar en escenarios interculturales y escuchar y leer de forma efectiva, con sensibilidad hacia las diferencias culturales. Estos resultados invitan a impulsar la cooperación entre profesores y universidades de distintos países, de cara a plantear actividades académicas conjuntas que faciliten la formación en competencias de sus estudiantes.

  5. Ventilation/perfusion SPECT or SPECT/CT for lung function imaging in patients with pulmonary emphysema?

    Science.gov (United States)

    Froeling, Vera; Heimann, Uwe; Huebner, Ralf-Harto; Kroencke, Thomas J; Maurer, Martin H; Doellinger, Felix; Geisel, Dominik; Hamm, Bernd; Brenner, Winfried; Schreiter, Nils F

    2015-07-01

    To evaluate the utility of attenuation correction (AC) of V/P SPECT images for patients with pulmonary emphysema. Twenty-one patients (mean age 67.6 years) with pulmonary emphysema who underwent V/P SPECT/CT were included. AC/non-AC V/P SPECT images were compared visually and semiquantitatively. Visual comparison of AC/non-AC images was based on a 5-point likert scale. Semiquantitative comparison assessed absolute counts per lung (aCpLu) and lung lobe (aCpLo) for AC/non-AC images using software-based analysis; percentage counts (PC = (aCpLo/aCpLu) × 100) were calculated. Correlation between AC/non-AC V/P SPECT images was analyzed using Spearman's rho correlation coefficient; differences were tested for significance with the Wilcoxon rank sum test. Visual analysis revealed high conformity for AC and non-AC V/P SPECT images. Semiquantitative analysis of PC in AC/non-AC images had an excellent correlation and showed no significant differences in perfusion (ρ = 0.986) or ventilation (ρ = 0.979, p = 0.809) SPECT/CT images. AC of V/P SPECT images for lung lobe-based function imaging in patients with pulmonary emphysema do not improve visual or semiquantitative image analysis.

  6. Hacia la construcción del trabajo en red para una universidad saludable. Balance del “I Foro internacional sobre experiencias en universidad saludable”

    OpenAIRE

    Virginia, García Sánchez; Jackeline, Ospina Rodríguez

    2009-01-01

    Esta compilación busca favorecer el trabajo en red de las instituciones universitarias que promueven la actividad física como elemento esencial de la salud de su comunidad. También se orienta a socializar los resultados del I Foro Internacional de experiencias en universidad saludable, como avance del trabajo interinstitucional que se promovió durante el evento, con aportes de expertos internacionales, nacionales y las experiencias de las universidades. Este material, va dirigido a todas las ...

  7. The Use of Quantitative SPECT/CT Imaging to Assess Residual Limb Health

    Science.gov (United States)

    2017-10-01

    of secondary health ef- fects following traumatic extremity injuries places a significant physical and psychosocial burden on SMs with LL and LS...been reported as the most important health -related physical condition con- tributing to a reduced QoL among veterans who had sustained a traumatic...AWARD NUMBER: W81XWH-15-1-0669 TITLE: The Use of Quantitative SPECT/CT Imaging to Assess Residual Limb Health PRINCIPAL INVESTIGATOR

  8. Liberación y desautomatización. La experiencia mística en perspectiva naturalizada

    Directory of Open Access Journals (Sweden)

    Lina Marcela Cadavid Ramírez

    2014-01-01

    Full Text Available Tradicionalmente, la experiencia mística tiene como uno de sus propósitos fundamentales alcanzar la liberación. Esta puede entenderse como el resultado de la superación de los condicionamientos del ego que permite el encuentro con nuestra mismidad. Se analiza la liberación desde un discurso epistemológico naturalizado, entendiéndola como un proceso de desautomatización que repercute sobre el sistema nervioso central y que suscita una transformación radical en la relación habitual que el hombre tiene con el mundo.

  9. El tratamiento de los estereotipos en el aula de ELE: una experiencia práctica

    Directory of Open Access Journals (Sweden)

    Elena Jiménez García

    2009-01-01

    Full Text Available En la docencia de español como lengua extranjera es fundamental el tratamiento de los estereotipos con el objetivo de favorecer el reconocimiento del contexto sociocultural de la lengua de aprendizaje y evitar una visión distorsionada que se aleje de la realidad.Nos hemos planteado ofrecer una posible panorámica de cómo enfocar estos aspectos en el aula de E/LE, basándonos en nuestra experiencia práctica con dos grupos de estudiantes de nivel B1: un grupo de nueve estudiantes universitarios alemanes y otro grupo de doce estudiantes preuniversitarios ingleses.

  10. El tratamiento de los estereotipos en el aula de ELE: una experiencia práctica

    Directory of Open Access Journals (Sweden)

    Elena Jiménez García

    2012-08-01

    Full Text Available En la docencia de español como lengua extranjera es fundamental el tratamientode los estereotipos con el objetivo de favorecer el reconocimiento del contextosociocultural de la lengua de aprendizaje y evitar una visión distorsionada que se alejede la realidad.Nos hemos planteado ofrecer una posible panorámica de cómo enfocar estosaspectos en el aula de E/LE, basándonos en nuestra experiencia práctica con dos gruposde estudiantes de nivel B1: un grupo de nueve estudiantes universitarios alemanes y otrogrupo de doce estudiantes preuniversitarios ingleses.

  11. Evaluation of attenuation and scatter correction requirements in small animal PET and SPECT imaging

    Science.gov (United States)

    Konik, Arda Bekir

    Positron emission tomography (PET) and single photon emission tomography (SPECT) are two nuclear emission-imaging modalities that rely on the detection of high-energy photons emitted from radiotracers administered to the subject. The majority of these photons are attenuated (absorbed or scattered) in the body, resulting in count losses or deviations from true detection, which in turn degrades the accuracy of images. In clinical emission tomography, sophisticated correction methods are often required employing additional x-ray CT or radionuclide transmission scans. Having proven their potential in both clinical and research areas, both PET and SPECT are being adapted for small animal imaging. However, despite the growing interest in small animal emission tomography, little scientific information exists about the accuracy of these correction methods on smaller size objects, and what level of correction is required. The purpose of this work is to determine the role of attenuation and scatter corrections as a function of object size through simulations. The simulations were performed using Interactive Data Language (IDL) and a Monte Carlo based package, Geant4 application for emission tomography (GATE). In IDL simulations, PET and SPECT data acquisition were modeled in the presence of attenuation. A mathematical emission and attenuation phantom approximating a thorax slice and slices from real PET/CT data were scaled to 5 different sizes (i.e., human, dog, rabbit, rat and mouse). The simulated emission data collected from these objects were reconstructed. The reconstructed images, with and without attenuation correction, were compared to the ideal (i.e., non-attenuated) reconstruction. Next, using GATE, scatter fraction values (the ratio of the scatter counts to the total counts) of PET and SPECT scanners were measured for various sizes of NEMA (cylindrical phantoms representing small animals and human), MOBY (realistic mouse/rat model) and XCAT (realistic human model

  12. Frequencies and implications of discordant findings of interictal SPECT and itcal SPECT in patients with intractable epilepsy

    International Nuclear Information System (INIS)

    Lee, D. S.; Lee, S. K.; Jeong, J. K.; Lee, M. C.; Ko, C. S.

    1997-01-01

    Interictal SPECT could be used at best as a reference image to ictal SPECT, and cause sometimes confusion if it had given unexplained discordant findings from ictal SPECT. We investigated implications of discordant findings which occurred in 26 among 268 which found their epileptogenic zones using ictal EEG and/or operative outcome. Sensitivity of interictal SPECT was only 36%. Among these 268, 69 patients had no structural lesions on MR, 14 of whom had decreased perfusion on interictal SPECT (8 trues and 6 falses (adjacent or contralateral)). Structural lesion were found in 199 on MR, 103 of whom had decreased perfusion (89 trues and 14 falses). Among 26 having discordant cases, 10 interictal SPECT were proved wrong after operation and/or invasive EEG and the other 16 were on speculation using PET and ictal EEG. Ictal hyperperfusion was observed in 14 patients in these interictal SPECT. Six ictal studies were found postictal accompanied by contralateral propagation or not. Two patients had dual pathology, and the remaining 2 unknown. Interictal SPECT was done on the 2nd day after ictal study(24), the 3rd day (18), the 4th day(16), the 5th day (23). Four among 24 interictal studies (17%) of the 2nd day and the other 4 among 57 of 3rd to 5th day revealed ictal hyperperfusion on interictal SPECT. Six interictal studies (2.7% among 221) acquired on the indifferent day showed also ictal hyperperfusion. We could suggest that the next day is not desirable for interictal SPECT after ictal study, as ictal hyperperfusion on interictal study confounded more than postictal findings of ictal SPECT in the discrete localization than reassuring ictal study

  13. Frequencies and implications of discordant findings of interictal SPECT and itcal SPECT in patients with intractable epilepsy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, D S; Lee, S K; Jeong, J K; Lee, M C; Ko, C S [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of)

    1997-07-01

    Interictal SPECT could be used at best as a reference image to ictal SPECT, and cause sometimes confusion if it had given unexplained discordant findings from ictal SPECT. We investigated implications of discordant findings which occurred in 26 among 268 which found their epileptogenic zones using ictal EEG and/or operative outcome. Sensitivity of interictal SPECT was only 36%. Among these 268, 69 patients had no structural lesions on MR, 14 of whom had decreased perfusion on interictal SPECT (8 trues and 6 falses (adjacent or contralateral)). Structural lesion were found in 199 on MR, 103 of whom had decreased perfusion (89 trues and 14 falses). Among 26 having discordant cases, 10 interictal SPECT were proved wrong after operation and/or invasive EEG and the other 16 were on speculation using PET and ictal EEG. Ictal hyperperfusion was observed in 14 patients in these interictal SPECT. Six ictal studies were found postictal accompanied by contralateral propagation or not. Two patients had dual pathology, and the remaining 2 unknown. Interictal SPECT was done on the 2nd day after ictal study(24), the 3rd day (18), the 4th day(16), the 5th day (23). Four among 24 interictal studies (17%) of the 2nd day and the other 4 among 57 of 3rd to 5th day revealed ictal hyperperfusion on interictal SPECT. Six interictal studies (2.7% among 221) acquired on the indifferent day showed also ictal hyperperfusion. We could suggest that the next day is not desirable for interictal SPECT after ictal study, as ictal hyperperfusion on interictal study confounded more than postictal findings of ictal SPECT in the discrete localization than reassuring ictal study.

  14. Flipped Classroom en un aula de música de Primaria: implementación y análisis de una experiencia de innovación docente.

    Directory of Open Access Journals (Sweden)

    Francisco Jesús Parra Giménez

    2017-05-01

    Full Text Available Con el avance tecnológico y su integración en los procesos de enseñanza - aprendizaje en los centros educativos, aparecen nuevas metodologías apoyadas en las tecnologías de la información y comunicación (TIC de aquí en adelante, entre la que se encuentra Flipped Classroom o Aula Invertida. Nuevos escenarios de enseñanza y aprendizaje, que con el apoyo de las TIC,  permiten una educación centrada en el alumnado y  una educación acorde con la sociedad actual. La metodología de trabajo Flipped Classroom permite  enseñar a los alumnos con las herramientas telemáticas que forman parte de su realidad más próxima y entre las que están creciendo. Por ello, con este artículo se pretende dar a conocer los resultados de una experiencia de innovación docente basada en la metodología Flipped Classroom en el área de Educación Musical, con el alumnado de 4º curso de Educación Primaria. Tras el diseño y puesta en práctica de la Unidad Didáctica “Célebres Compositores”, se han obtenido una serie de resultados a través de diversas técnicas e instrumentos de recogida de información, como son los cuestionarios y la ficha de observación, que han permitido una evaluación positiva de dicha experiencia, así como comprobar que la metodología Flipped Classroom resulta interesante para futuras investigaciones y estudios en Educación Primaria. A continuación, se exponen los datos más relevantes y los resultados obtenidos de dicha experiencia.

  15. Proyectos Urbanos Estratégicos para Valparaíso: una Experiencia Académica

    Directory of Open Access Journals (Sweden)

    Eliana Muga

    2016-12-01

    Full Text Available El presente artículo expone una experiencia académica del Taller de Arquitectura orientada al diseño urbano a través del desarrollo de Proyectos Urbanos Estratégicos en quebradas, donde el tema es la ordenación del territorio, sobre la base de la puesta en valor del patrimonio local (comprender y actuar en relación con la cultura local y vocación de estos territorios con miras a alcanzar un desarrollo sustentable para los cerros en Valparaíso, Chile. La relevancia práctica es revertir los procesos de marginalidad, asociados con diversos problemas ambientales como microbasurales, ocupación ilegal de terrenos y peligro de incendios, a través de la generación de nuevas centralidades urbanas y el cuidado de las quebradas con su ocupación y manejo.

  16. Videojuegos y aprendizaje colaborativo. Experiencias en torno a la etapa de Educación Primaria.

    Directory of Open Access Journals (Sweden)

    Marta MARTÍN DEL POZO

    2015-07-01

    Full Text Available Los videojuegos no son solamente una forma de entretenimiento, sino también pueden ser utilizados como recurso educativo para el aprendizaje. En este sentido, el objetivo de este artículo es llevar a cabo una revisión sistemática sobre experiencias e investigaciones del uso de videojuegos en la etapa de Educación Primaria (es decir, con alumnado de 6 a 12 años, pero, de manera particular, experiencias con un enfoque de aprendizaje colaborativo, y también con una evaluación pre y post del aprendizaje que muestre si los alumnos consiguieron ganancias de aprendizaje. Para conseguir dicho objetivo, el artículo está dividido en cinco secciones que muestran los principales aspectos relacionados con este tema: videojuegos en educación, aprendizaje colaborativo, la metodología para la revisión sistemática, resultados y conclusiones. Como resultado, 8 estudios cumplían los criterios de inclusión y fueron seleccionados para el análisis. En este sentido, mostramos que los videojuegos pueden ser utilizados bajo un enfoque de aprendizaje-trabajo colaborativo, en contraste a la idea extendida de que los videojuegos generan personas aisladas, sobre todo en el caso de los menores, y además, en general, los alumnos consiguen mejoras en su aprendizaje. En conclusión, los videojuegos pueden ser un buen recurso para el proceso de aprendizaje y, por ejemplo, pueden ser utilizados dentro de un enfoque de aprendizaje colaborativo pero es necesaria más información sobre esto debido a los límites que mostramos al final del artículo, como, por ejemplo, la necesidad de más estudios con evaluación pre y post de los logros de aprendizaje y que usen grupos de control y experimental.

  17. Relaciones diferenciales entre experiencias de alfabetización y habilidades de alfabetización emergente

    Directory of Open Access Journals (Sweden)

    Liliana Salazar-Reyes

    2013-08-01

    Full Text Available El objetivo del estudio fue investigar si las experiencias de alfabetización que los padres brindan se relacionan diferencialmente con la alfabetización de los niños. A partir de una muestra intencional, se seleccionaron treinta y cuatro diadas madre-hijo al inicio de preescolar, procedentes de una escuela particular del Estado de México. Se presenta evidencia que considera en un mismo estudio el análisis de las experiencias explícitas e implícitas observadas en una sesión de interacción madre-hijo, haciendo uso de diferentes materiales, y otro tipo de experiencias de alfabetización reportadas por las madres. Ambos resultados se complementaron para comparar los puntajes obtenidos por los niños en las pruebas de alfabetización emergente. Se constataron diferencias significativas en la alfabetización debidas a la escolaridad del padre t(11 = 2,78, p = 0,019; el acercamiento a los libros t(12 = 3,90, p = 0,001, y la frecuencia de lectura de cuentos t(12 = 4,31, p = 0,002. A partir de los resultados se concluye que algunos niños tienen habilidades de alfabetización desde muy temprana edad como resultado de las experiencias que sus padres les proporcionan.

  18. Ciberfeminismo de investigacción con y entre tecnoartistas y hackers

    Directory of Open Access Journals (Sweden)

    Núria Vergés Bosch

    2014-12-01

    Full Text Available Investigar la relación de los géneros y las nuevas tecnologías de la información y comunicación toma importancia con el desarrollo de la sociedad actual. Desde nuestro colectivo llevamos a cabo una serie de investigaciones orientadas hacia la formulación, análisis y desarrollo de acciones desde, con y para las relaciones de las mujeres y las TIC. Por las características de las experiencias, temáticas y metodologías que tratamos hemos ido desarrollando lo que llamamos ciberfeminismo de investigacción. Para este artículo proponemos continuar explorando y mostrando nuestros procesos de investigacción ciberfeminista. Partimos de los inicios de nuestras investigacciones hasta el momento actual e incidimos en algunos aspectos que se visibilizan mejor a través de investigaciones específicas y de forma comparada. Nos centraremos, por un lado, en la investigación LeLeLArtrt (LeLArt sobre las experiencias y trayectorias TIC de las tecnoartistas y, por el otro, en LeLaCoders (LeLaCoders, sobre las experiencias y trayectorias TIC de las mujeres desarrolladoras de software libre y/o hackers.

  19. An accurate projection algorithm for array processor based SPECT systems

    International Nuclear Information System (INIS)

    King, M.A.; Schwinger, R.B.; Cool, S.L.

    1985-01-01

    A data re-projection algorithm has been developed for use in single photon emission computed tomography (SPECT) on an array processor based computer system. The algorithm makes use of an accurate representation of pixel activity (uniform square pixel model of intensity distribution), and is rapidly performed due to the efficient handling of an array based algorithm and the Fast Fourier Transform (FFT) on parallel processing hardware. The algorithm consists of using a pixel driven nearest neighbour projection operation to an array of subdivided projection bins. This result is then convolved with the projected uniform square pixel distribution before being compressed to original bin size. This distribution varies with projection angle and is explicitly calculated. The FFT combined with a frequency space multiplication is used instead of a spatial convolution for more rapid execution. The new algorithm was tested against other commonly used projection algorithms by comparing the accuracy of projections of a simulated transverse section of the abdomen against analytically determined projections of that transverse section. The new algorithm was found to yield comparable or better standard error and yet result in easier and more efficient implementation on parallel hardware. Applications of the algorithm include iterative reconstruction and attenuation correction schemes and evaluation of regions of interest in dynamic and gated SPECT

  20. Química recreativa con agua oxigenada

    Directory of Open Access Journals (Sweden)

    Mª Luisa Aguilar Muñoz

    2011-01-01

    Full Text Available Con el objeto de despertar el interés por la química así como de tratar diversos conceptos químicos y biológicos, presentamos la reacción de descomposición catalítica del agua oxigenada (H2O2 en tres experiencias diferentes y con distintos catalizadores. Esta reacción es muy exotérmica, produciendo agua y oxígeno. En la primera experiencia, se mezclan en una probeta la disolución de agua oxigenada y un poco de lavavajillas. Al añadir yoduro de potasio, éste actúa como catalizador y aparece gran cantidad de espuma debido al oxígeno desprendido en la reacción. En la segunda, se utiliza como catalizador un óxido de manganeso finamente dividido, que al dejarlo caer en el recipiente que contiene agua oxigenada, produce un espectacular chorro de vapor de agua. En la última, se produce una llamativa reacción luminiscente entre el peróxido de hidrógeno y el luminol utilizando como catalizador el ión hierro contenido en el hexacianoferrato (III de potasio (ferricianuro de potasio.

  1. HMPAO-SPECT in cerebral seizures

    International Nuclear Information System (INIS)

    Gruenwald, F.; Bockisch, A.; Reichmann, K.; Ammari, B.; Hotze, A.; Biersack, H.J.; Durwen, H.; Buelau, P.; Elger, C.E.; Rohde, A.; Penin, H.

    1988-01-01

    In nine patients with suspected psychogenic seizures and in three patients with proven epileptic seizures HMPAO-SPECT was performed prior to and during seizure. In the patients with lateron-proven psychogenic seizures no, or only slight, changes of regional cerebral blood flow were found. Patients with proven epilepsy revealed partly normal findings interictally but during seizure a markedly increased circumscript blood flow was found in all patients. Even though PET is superior to SPECT with respect to spatial resolution, in the diagnosis of seizures HMPAO-SPECT has the advantage of enabling injection of the tracer during the seizure and the performance of the SPECT study subsequently. (orig.) [de

  2. Efficient simulation of voxelized phantom in GATE with embedded SimSET multiple photon history generator

    Science.gov (United States)

    Lin, Hsin-Hon; Chuang, Keh-Shih; Lin, Yi-Hsing; Ni, Yu-Ching; Wu, Jay; Jan, Meei-Ling

    2014-10-01

    GEANT4 Application for Tomographic Emission (GATE) is a powerful Monte Carlo simulator that combines the advantages of the general-purpose GEANT4 simulation code and the specific software tool implementations dedicated to emission tomography. However, the detailed physical modelling of GEANT4 is highly computationally demanding, especially when tracking particles through voxelized phantoms. To circumvent the relatively slow simulation of voxelized phantoms in GATE, another efficient Monte Carlo code can be used to simulate photon interactions and transport inside a voxelized phantom. The simulation system for emission tomography (SimSET), a dedicated Monte Carlo code for PET/SPECT systems, is well-known for its efficiency in simulation of voxel-based objects. An efficient Monte Carlo workflow integrating GATE and SimSET for simulating pinhole SPECT has been proposed to improve voxelized phantom simulation. Although the workflow achieves a desirable increase in speed, it sacrifices the ability to simulate decaying radioactive sources such as non-pure positron emitters or multiple emission isotopes with complex decay schemes and lacks the modelling of time-dependent processes due to the inherent limitations of the SimSET photon history generator (PHG). Moreover, a large volume of disk storage is needed to store the huge temporal photon history file produced by SimSET that must be transported to GATE. In this work, we developed a multiple photon emission history generator (MPHG) based on SimSET/PHG to support a majority of the medically important positron emitters. We incorporated the new generator codes inside GATE to improve the simulation efficiency of voxelized phantoms in GATE, while eliminating the need for the temporal photon history file. The validation of this new code based on a MicroPET R4 system was conducted for 124I and 18F with mouse-like and rat-like phantoms. Comparison of GATE/MPHG with GATE/GEANT4 indicated there is a slight difference in energy

  3. La Sociedad Española de Cirugía Plástica viaja a África: mi experiencia en Togo y Liberia

    Directory of Open Access Journals (Sweden)

    Elena Lorda-Barraguer

    Full Text Available En este artículo pretendo explicar mi experiencia en 5 campañas quirúrgicas en África. El último de estos viajes en noviembre de 2016 supuso el inicio de la cooperación internacional de la Sociedad Española de Cirugía Plástica, Reparadora y Estética en ese continente. También, dejar constancia de que es posible llevar a cabo una cirugía reconstructiva eficaz con recursos limitados si se cuenta con un buen apoyo logístico local. Y de lo necesaria que es nuestra cirugía capaz de mejorar la calidad de vida de muchos pacientes, lo que se pone de manifiesto incluso en estas expediciones sanitarias aunque sean de corta duración. Una vez registrada nuestra casuística, constatamos que los procesos patológicos intervenidos con más frecuencia son las secuelas de quemaduras, el labio leporino y las úlceras. Describo las condiciones de trabajo que hemos encontrado para facilitar futuras expediciones de otros colegas a quienes recomiendo encarecidamente esta experiencia.

  4. Quantification of left ventricular regional functions using ECG-gated myocardial perfusion SPECT. Validation of left ventricular systolic functions

    International Nuclear Information System (INIS)

    Yamamoto, Akira; Takahashi, Naoto; Iwahara, Shin-ichiro; Munakata, Kazuo; Hosoya, Tetsuo

    2006-01-01

    We have developed a program to quantify regional left ventricular (LV) function and wall motion synchrony using electrocardiogram (ECG)-gated myocardial perfusion SPECT (MPS). This preliminary study was undertaken to validate the use of this program for estimating regional LV systolic function. Patients were subjected to MPS by 99m Tc-sestamibi at rest. The study included 20 patients who were confirmed to have a low probability of coronary artery disease (LPG; low probability group), 19 heart disease patients who were examined by MPS and equilibrium radionuclide angiography (ERNA) (ERG; ERNA group), and 24 patients who were examined by MPS and 2-dimensional echocardiography (2DE) (2DEG; 2DE group). The values of the ejection fraction (EF) and peak ejection rate (PER) were estimated. The global functions evaluated by this program were compared with those obtained by ERNA in the ERG. For regional assessment, the reference values of the functional indices were obtained for 17 LV segments in LPG. The Z score, (reference average value of the segment-patient's value of the segment)/reference standard deviation of the segment, was used for the evaluation of regional functions; a score equal to or greater than 2 was defined as abnormal. Semiquantitative visual interpretation of 2DE was used as the standard to assess wall motion. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of these criteria and the relationship between 2DE grading and Z scoring were validated in 2DEG. The values of the global EF and PER evaluated by this program correlated with those determined by ERNA (r=0.76 and 0.58, respectively; p -10 ). The potential of this program to quantify the regional systolic function was validated. (author)

  5. EL CUERPO INVESTIGADOR, EL CUERPO INVESTIGADO. Una aproximación fenomenológica a la experiencia del puerperio

    Directory of Open Access Journals (Sweden)

    ANA SABRINA MORA

    2009-01-01

    Full Text Available El OBJETIVO DE ESTE ARTÍCULO ES EXPLORAR LA UTILIDAD DE LAS DESCRIPCIONES FENOMENOLÓGIcas, incluyendo las experiencias de quien realiza la investigación, como parte de los análisis socioantropológicos sobre el cuerpo y la sexualidad, en especial, para aproximarse al estudio del puerperio y a algunas experiencias que suelen asociarse a él en la contemporaneidad occidental. Intenta, además, integrar la propuesta metodológica de la fenomenología con los marcos analíticos postestructuralistas. Se parte de la idea de que la observación de acontecimientos vitales intensos como el parto y elpuerperio, es una vía de acceso al conocimiento de todas aquellas experiencias que desde el cuerpo repercuten sobre la subjetividad, y considera al cuerpo y al sujeto como una unidad indisoluble, que sólo puede comprenderse desde su imbricación, tal como lo establece la perspectiva del embodiment.

  6. Dopamine transporter imaging with [{sup 123}I]FP-CIT SPECT: potential effects of drugs

    Energy Technology Data Exchange (ETDEWEB)

    Booij, Jan [University of Amsterdam, Department of Nuclear Medicine, Academic Medical Center, Amsterdam (Netherlands); Kemp, Paul [Southampton University Hospitals Trust, Department of Nuclear Medicine, Southampton (United Kingdom)

    2008-02-15

    [{sup 123}I]N-{omega}-fluoropropyl-2{beta}-carbomethoxy-3{beta}-{l_brace}4-iodophenyl{r_brace}nortropane ([{sup 123}I]FP-CIT) single photon emission computed tomography (SPECT) is a frequently and routinely used technique to detect or exclude dopaminergic degeneration by imaging the dopamine transporter (DAT) in parkinsonian and demented patients. This technique is also used in scientific studies in humans, as well as in preclinical studies to assess the availability of DAT binding in the striatum. In routine clinical studies, but also in scientific studies, patients are frequently on medication and sometimes even use drugs of abuse. Moreover, in preclinical studies, animals will be anesthetized. Prescribed drugs, drugs of abuse, and anesthetics may influence the visual interpretation and/or quantification of [{sup 123}I]FP-CIT SPECT scans. Here, we discuss the basic principle of how drugs and anesthetics might influence the visual interpretation and/or quantification of [{sup 123}I]FP-CIT SPECT scans. We also review drugs which are likely to have a significant influence on the visual interpretation and/or quantification of [{sup 123}I]FP-CIT SPECT scans. Additionally, we discuss the evidence as to whether frequently prescribed drugs in parkinsonian and demented patients may have an influence on the visual interpretation and/or quantification of [{sup 123}I]FP-CIT SPECT scans. Finally, we discuss our recommendations as to which drugs should be ideally withdrawn before performing a [{sup 123}I]FP-CIT SPECT scan for routine clinical purposes. The decision to withdraw any medication must always be made by the specialist in charge of the patient's care and taking into account the pros and cons of doing so. (orig.)

  7. Actividades en la adolescencia: Experiencias óptimas y autopercepciones

    Directory of Open Access Journals (Sweden)

    Alejandra Daniela Calero

    2016-12-01

    Full Text Available El objetivo de este trabajo fue comparar los niveles de experiencias óptimas (EO que los adolescentes reportan en distintas actividades del contexto escolar y extraescolar y analizar cómo se relacionan estos niveles con el autoconcepto y autoestima en la población adolescente de la Ciudad Autónoma de Buenos Aires, Argentina (CABA-AR. Para ello se administró el Inventario Breve de EO y el Perfil de Autopercepción a 399 adolescentes concurrentes a escuelas de educación media de la CABA-AR. Se realizó un ANOVA de medidas repetidas con efecto principal intrasujeto para comparar las EO en cada actividad y un análisis de correlación para estudiar la relación entre EO y el autoconcepto y autoestima. Entre los resultados se encontró que los adolescentes experimentan mayores niveles de ocurrencia de EO en las actividades extracurriculares. Con respecto al autoconcepto y autoestima, las relaciones halladas fueron en todos los casos positivas y mostraron diferencias según el tipo de actividad en el cual se reportaban las EO.

  8. Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging

    International Nuclear Information System (INIS)

    Boogers, Mark J.; Veltman, Caroline E.; Chen, Ji; Garcia, Ernest V.; Bommel, Rutger J. van; Mooyaart, Eline A.Q.; Wall, Ernst E. van der; Schalij, Martin J.; Bax, Jeroen J.; Delgado, Victoria; Younis, Imad Al; Hiel, Bernies van der; Dibbets-Schneider, Petra

    2011-01-01

    The aim of the current study was to evaluate the feasibility of phase analysis on gated myocardial perfusion SPECT (GMPS) for the assessment of left ventricular (LV) diastolic dyssynchrony in a head-to-head comparison with tissue Doppler imaging (TDI). The population consisted of patients with end-stage heart failure of New York Heart Association functional class III or IV with a reduced LV ejection fraction of ≤35%. LV diastolic dyssynchrony was calculated using TDI as the maximal time delay between early peak diastolic velocities of two opposing left ventricle walls (diastolic mechanical delay). Significant LV diastolic dyssynchrony was defined as a diastolic mechanical delay of >55 ms on TDI. Furthermore, phase analysis on GMPS was performed to evaluate LV diastolic dyssynchrony; diastolic phase standard deviation (SD) and histogram bandwidth (HBW) were used as markers of LV diastolic dyssynchrony. A total of 150 patients (114 men, mean age 66.0 ± 10.4 years) with end-stage heart failure were enrolled. Both diastolic phase SD (r = 0.81, p 55 ms) showed significantly larger diastolic phase SD (68.1 ± 13.4 vs. 40.7 ± 14.0 , p < 0.01) and diastolic HBW (230.6 ± 54.3 vs. 129.0 ± 55.6 , p < 0.01) as compared to patients without LV diastolic dyssynchrony on TDI (≤55 ms). Finally, phase analysis on GMPS showed a good intra- and interobserver reproducibility for the determination of diastolic phase SD (ICC 0.97 and 0.88) and diastolic HBW (ICC 0.98 and 0.93). Phase analysis on GMPS showed good correlations with TDI for the assessment of LV diastolic dyssynchrony. (orig.)

  9. Can perfusion SPECT aid CTPA interpretation?

    International Nuclear Information System (INIS)

    Gradinscak, D. J.; Roach, P.; Bailey, E.; Kueh, S.

    2009-01-01

    Full text:Objective: To determine whether fusion of perfusion SPECT and CTPA improves the diagnostic accuracy of CTPA. Methods: 35 patients with suspected PE who underwent both CTPA and SPECT V/Q within 48 hours were included. Of these, the majority (n=30) had PE as determined by the V/Q SPECT scan and the others (n=5) were negative for PE. The clinical reports of CTPA were reviewed and pulmonary emboli tabulated based on anatomical location. A second radiologist, blinded to the results of the clinical read and the V/Q SPECT scan, reviewed the CTPA with and without perfusion SPECT fusion for assistance. Results: A total 57 PE were reported on the clinical reports and 60 PE identified on the blinded read. Fused CTPA/perfursion SPECT images identified a further 5 PE not identified on the clinical read (8% increase) and 2 PE not identified on the blinded read (3% increase). The additional emboli detected resulted in a change in final diagnosis from PE negative to PE positive in 2 patients (6%) compared with the clinical read and 1 patient (3%) compared with the blinded read without SPECT fusion. Conclusion: Fused CTPA-SPECT perfusion improves the sensitivity of CTPA for the detection of PE in a small number of patients. Fused data may help guide the radiologist to identify sites of PE on CTPA.

  10. Diagnostic role of (99)Tc(m)-MDP SPECT/CT combined SPECT/MRI Multi modality imaging for early and atypical bone metastases.

    Science.gov (United States)

    Chen, Xiao-Liang; Li, Qian; Cao, Lin; Jiang, Shi-Xi

    2014-01-01

    The bone metastasis appeared early before the bone imaging for most of the above patients. (99)Tc(m)-MDP ((99)Tc(m) marked methylene diphosphonate) bone imaging could diagnosis the bone metastasis with highly sensitivity, but with lower specificity. The aim of this study is to explore the diagnostic value of (99)Tc(m)-MDP SPECT/CT combined SPECT/MRI Multi modality imaging for the early period atypical bone metastases. 15 to 30 mCi (99)Tc(m)-MDP was intravenously injected to the 34 malignant patients diagnosed as doubtful early bone metastases. SPECT, CT and SPECT/CT images were captured and analyzed consequently. For the patients diagnosed as early period atypical bone metastases by SPECT/CT, combining the SPECT/CT and MRI together as the SPECT/MRI integrated image. The obtained SPECT/MRI image was analyzed and compared with the pathogenic results of patients. The results indicated that 34 early period doubtful metastatic focus, including 34 SPECT positive focus, 17 focus without special changes by using CT method, 11 bone metastases focus by using SPECT/CT method, 23 doubtful bone metastases focus, 8 doubtful bone metastases focus, 14 doubtful bone metastases focus and 2 focus without clear image. Totally, SPECT/CT combined with SPECT/MRI method diagnosed 30 bone metastatic focus and 4 doubtfully metastatic focus. In conclusion, (99)Tc(m)-MDP SPECT/CT combined SPECT/MRI Multi modality imaging shows a higher diagnostic value for the early period bone metastases, which also enhances the diagnostic accuracy rate.

  11. ERRORES FRECUENTES EN EL DIAGNÓSTICO Y TRATAMIENTO DE LOS PACIENTES CON ENFERMEDAD INFLAMATORIA INTESTINAL

    Directory of Open Access Journals (Sweden)

    JAIME LUBASCHER C., DR.

    2015-09-01

    Full Text Available El creciente aumento de pacientes con enfermedad inflamatoria intestinal (EII, sumado a la multiplicidad de alternativas terapéuticas y a la poca experiencia en general de los médicos para tratar estas patologías, ya que son enfermedades emergentes, ha facilitado que se cometan errores tanto en el diagnóstico como en el tratamiento de las EII. En este artículo, se presentarán los más frecuentes e importantes, según la experiencia del autor, con el objeto de corregir estas conductas y alertar a los equipos médicos sobre éstas. El listado incluye errores cometidos en la historia clínica, laboratorio general, endoscopia y tratamiento.

  12. 99mTc-HMPAO Brain SPECT in Seizure Disorder: Comparison Brain SPECT, MRI / CT and EEG

    International Nuclear Information System (INIS)

    Yang, Hyung In; Im, Ju Hyuk; Choi, Chang Woon; Lee, Dong Soo; Chung, June Key; No, Jae Kyu; Lee, Myung Chul; Koh, Chang Soon

    1994-01-01

    We studied 115 patients with seizure who had been performed brain SPECT brain MRI of CT and EEG. To evaluate the pattern of brain SPECT in seizure patients 28 of them had secondary epilepsies, 87 had primary epilepsies. In primary epilepsies, 42 were generalized seizure and 45 were partial seizure. The causes of secondary epilepsies were congenital malformation, cerebromalacia, cerebral infarction ultiple sclerosis, AV-malformation. granuloma and etc, in order. In 28 secondary epilepsies, 25 of them, brain SPECT lesions was concordant with MRI or CT lesions. 3 were disconcordant. The brain SPECT findings of generalized seizure were normal in 22 patients, diffuse irregular decreased perfusion in 8, decreased in frontal cortex in 4. temporal in 5 and frontotemporal in 3. In 45 partial seizure, 19 brain SPECT were concordant with EEG (42.4%).

  13. Experiencias con distrofia simpática refleja

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    John Jairo Hernández Castro

    1993-07-01

    Full Text Available Se presentan 30 pacientes con distrofia simpática refleja vistos en la Clínica del Dolor del Hospital San Juan de Dios de Santafé de Bogotá, entre enero de 1992 y julio de 1993. La mayoría de los enfermos son hombres entre los 20 y los 40 años. La causa de la entidad, en el 66.6% de los casos, es el trauma por proyectil de arma de fuego; los restantes fueron producidos per hernia discal lumbar, cirugía de hombro, operación cesárea, artroscopia de rodilla, herida cortante en mano, infarto del miocardio, ACV odusivo talámico, fractura de Colles, instrumentación de Luque y herida medular por arma cortante.

  14. SPECT-CT in the diagnosis of coronary artery disease; SPECT-CT in der Diagnostik der koronaren Herzerkrankung

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, M. [Klinik und Poliklinik fuer Nuklearmedizin, Klinikum der Univ. Muenchen (Germany)

    2006-09-15

    SPECT have a very low risk of death or fatal myocardial infarction (MI), therefore no intervention is required for these patients. According to the current guidelines for management of patients with chronic stable angina, both morphological and functional information about the coronary artery tree should be present before revascularization therapy is performed. The combination of 64-slice CT angiography plus gated myocardial SPECT could provide both non-invasive three-dimensional anatomical and functional information of the coronary artery tree. (orig.)

  15. Sequential SPECT/CT imaging starting with stress SPECT in patients with left bundle branch block suspected for coronary artery disease

    Energy Technology Data Exchange (ETDEWEB)

    Engbers, Elsemiek M.; Mouden, Mohamed [Isala, Department of Cardiology, Zwolle (Netherlands); Isala, Department of Nuclear Medicine, Zwolle (Netherlands); Timmer, Jorik R.; Ottervanger, Jan Paul [Isala, Department of Cardiology, Zwolle (Netherlands); Knollema, Siert; Jager, Pieter L. [Isala, Department of Nuclear Medicine, Zwolle (Netherlands)

    2017-01-15

    To investigate the impact of left bundle branch block (LBBB) on sequential single photon emission computed tomography (SPECT)/ CT imaging starting with stress-first SPECT. Consecutive symptomatic low- to intermediate-risk patients without a history of coronary artery disease (CAD) referred for SPECT/CT were included from an observational registry. If stress SPECT was abnormal, additional rest SPECT and, if feasible, coronary CT angiography (CCTA) were acquired. Of the 5,018 patients, 218 (4.3 %) demonstrated LBBB. Patients with LBBB were slightly older than patients without LBBB (65±12 vs. 61±11 years, p<0.001). Stress SPECT was more frequently abnormal in patients with LBBB (82 % vs. 46 %, p<0.001). After reviewing stress and rest images, SPECT was normal in 43 % of the patients with LBBB, compared to 77 % of the patients without LBBB (p<0.001). Sixty-four of the 124 patients with LBBB and abnormal stress-rest SPECT underwent CCTA (52 %), which could exclude obstructive CAD in 46 of the patients (72 %). Sequential SPECT/CT imaging starting with stress SPECT is not the optimal imaging protocol in patients with LBBB, as the majority of these patients have potentially false-positive stress SPECT. First-line testing using CCTA may be more appropriate in low- to intermediate-risk patients with LBBB. (orig.)

  16. La utilidad del monitoreo Holter con saturación de oxígeno en la valoración de pacientes con sospecha de apnea del sueño

    OpenAIRE

    Araya - Gómez, Vivien; Alpízar - Rivas, Rodolfo

    2014-01-01

    Justificación: los trastornos respiratorios asociados con el sueño son frecuentes. Entre ellos la apnea del sueño ocupa un lugar importante como problema de salud, pues está asociada con la aparición de arritmias, trastornos metabólicos, hipertensión arterial y cardiopatía isquémica. La detección tiene cierto grado de dificultad, puesto que métodos como la polisomnografía pueden ser complejos y costosos. El objetivo de este trabajo es presentar la experiencia con el uso del monitoreo ambulato...

  17. El poder del testimonio, experiencias de mujeres

    Directory of Open Access Journals (Sweden)

    Rosana Paula Rodríguez

    2013-09-01

    experiencia singular. Las palabras de las mujeres que relatan experiencias corporales nombran una dimensión fundamental de nuestra experiencia, la de la diferencia sexual produciendo un dislocamiento en la presunta neutralidad de la lengua. Se trata de una reflexión que abre la posibilidad de poner palabras a lo innombrable.

  18. EL RETO DIGITAL DE LOS MUSEOS COMO ENTORNOS DE EXPERIENCIA TURÍSTICA

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    Diolinda Ramírez Gutiérrez

    2014-10-01

    Full Text Available La presencia de los espacios de patrimonio en el medio digital es tanto una realidad imparable como una exigencia en incremento. La eficacia comunicativa no va emparejada a dicha presencia pero es condición para el cumplimiento del compromiso con la audiencia. El trabajo realizado elabora una lista de aspectos a evaluar en las webs de las instituciones, partiendo de consideraciones que la literatura académica del turismo hace sobre las características de la experiencia en contextos mediados por las tecnologías de la información y la comunicación. En este caso el análisis y evaluación es aplicado sobre las webs de museos de las islas del Archipiélago Canario (España con mayor afluencia turística mostrando déficits relacionados con el acceso, la planificación de la visita y las posibilidades de interactuación.

  19. Educación, Experiencia e Ingresos en el Sector Informal en Colombia

    Directory of Open Access Journals (Sweden)

    Augusto Peñaranda Sanjuán

    2004-06-01

    Full Text Available

    Introducción

    La teoría del capital humano muestra los ingresos de un trabajador como un retorno a los conocimientos adquiridos a través de los años de escolaridad y de experiencia laboral. Con los primeros trabajos de Becker (1966, y Hanoch (1967 se inició la literatura al respecto y posteriormente Mincer (1974 propuso una regresión lineal como una metodología para calcular la contribución de la escolaridad y la experiencia en los ingresos de los trabajadores. La ecuación de regresión de Mincer llamada “ función de ingresos”, incluye el logaritmo del ingreso como variable explicada y la escolaridad y los años de experiencia como variables explicatorias. Muchos estudiosos que siguieron al trabajo pionero de Mincer estiman que la ecuación de regresión de Mincer en diferentes contextos resaltan la importancia adicional de características de la comunidad en general , factores institucionales y otros atributos como raza, religión y genero. Otros estudios enfatizan sobre la importancia que tiene la antigüedad en el actual empleo sobre la antigüedad total en el mercado laboral, sugiriendo que en especial la antigüedad puede ser determinante en los ingresos del individuo. (Abraham 1987. (Psacharopolous 1985.

    En este trabajo queremos estimar la función de ingresos para el sector informal de los trabajadores en Colombia, durante el período comprendido entre 1988 y 1998, teniendo en cuenta las variables de escolaridad, experiencia y antigüedad laboral o permanencia en el último empleo. También queremos estimar la función de acuerdo con el género y con la variable escolaridad discriminada de acuerdo con el nivel de educación como primaria, bachillerato, universidad y * Magíster en Economía, Universidad Javeriana. Otorrinolaringólogo de la Fundación Santa Fe de Bogotá, Trabajo de ingreso a la Academia como Miembro Correspondiente. mayores, lo cual nos permite examinar las diferencias que existan y sus

  20. SPECT data acquisition and image reconstruction in a stationary small animal SPECT/MRI system

    Science.gov (United States)

    Xu, Jingyan; Chen, Si; Yu, Jianhua; Meier, Dirk; Wagenaar, Douglas J.; Patt, Bradley E.; Tsui, Benjamin M. W.

    2010-04-01

    The goal of the study was to investigate data acquisition strategies and image reconstruction methods for a stationary SPECT insert that can operate inside an MRI scanner with a 12 cm bore diameter for simultaneous SPECT/MRI imaging of small animals. The SPECT insert consists of 3 octagonal rings of 8 MR-compatible CZT detectors per ring surrounding a multi-pinhole (MPH) collimator sleeve. Each pinhole is constructed to project the field-of-view (FOV) to one CZT detector. All 24 pinholes are focused to a cylindrical FOV of 25 mm in diameter and 34 mm in length. The data acquisition strategies we evaluated were optional collimator rotations to improve tomographic sampling; and the image reconstruction methods were iterative ML-EM with and without compensation for the geometric response function (GRF) of the MPH collimator. For this purpose, we developed an analytic simulator that calculates the system matrix with the GRF models of the MPH collimator. The simulator was used to generate projection data of a digital rod phantom with pinhole aperture sizes of 1 mm and 2 mm and with different collimator rotation patterns. Iterative ML-EM reconstruction with and without GRF compensation were used to reconstruct the projection data from the central ring of 8 detectors only, and from all 24 detectors. Our results indicated that without GRF compensation and at the default design of 24 projection views, the reconstructed images had significant artifacts. Accurate GRF compensation substantially improved the reconstructed image resolution and reduced image artifacts. With accurate GRF compensation, useful reconstructed images can be obtained using 24 projection views only. This last finding potentially enables dynamic SPECT (and/or MRI) studies in small animals, one of many possible application areas of the SPECT/MRI system. Further research efforts are warranted including experimentally measuring the system matrix for improved geometrical accuracy, incorporating the co

  1. Percepciones del color y de la forma de los empaques: una experiencia de aprendizaje

    Directory of Open Access Journals (Sweden)

    Ana María Arboleda Arango

    2008-01-01

    Full Text Available midores al color y a la forma de los productos se crea a partir de su experiencia con los empaques y con el uso del producto. Este estudio analiza tal premisa de manera exploratoria, utilizando la metodología cualitativa de grupos focales. Así, los resultados sugieren que el hábito y la familiaridad del consumidor predisponen la búsqueda de ciertas características, en cuanto color y forma, que le permiten identificar el producto, sus atributos y su utilidad. Finalmente, dada la generalización que el consumidor hace de los símbolos, se recomienda conservar en los empaques códigos propios de la categoría para garantizar el reconocimiento del producto y evitar confusiones con los de otras categorías. Ante empaques con características diferentes a las de la categoría, se deben diseñar estrategias de comunicación para procurar el aprendizaje de nuevos símbolos.

  2. Despojo, materialidad y afectos: la experiencia del desplazamiento forzado entre mujeres triquis

    OpenAIRE

    Marinis, Natalia de

    2017-01-01

    Resumen: En los últimos años, debido a la escalada de violencia en México, académicos y organismos de derechos humanos han documentado numerosos casos de desplazamiento interno forzado, lo que plantea la urgencia de reconocimiento legal y asistencia de las personas desplazadas. En este artículo sintetizo estos avances y subrayo el aporte que la perspectiva etnográfica brinda al entendimiento de la experiencia traumática del desplazamiento forzado. A partir de una investigación etnográfica con...

  3. SPECT in psychiatry

    International Nuclear Information System (INIS)

    Kasper, S.; Gruenwald, F.; Walter, H.; Klemm, E.; Podreka, I.; Biersack, H.J.

    1994-01-01

    In the last fifteen years different attempts have been undertaken to understand the biological basis of major psychiatric disorders. One important tool to determine patterns of brain dysfunction is single emission computed tomography (SPECT). Whereas SPECT investigations are already a valuable diagnostic instrument for the diagnosis of dementia of the Alzheimer Type (DAT) there have not been consistent findings that can be referred to as specific for any other particular psychiatric diagnostic entity. Nevertheless, SPECT studies have been able to demonstrate evidence of brain dysfunction in patients with schizophrenia, depression, anxiety disorders, and substance abuse in which other methods showed no clear abnormality of brain function. Our manuscript reviews the data which are currently available in the literature and stresses the need for further studies, especially for prediction and monitoring psychiatric treatment modalities. (orig.) [de

  4. Proyecto innovador: “con+ciencia”

    OpenAIRE

    Fernández Arroyo, Jorge; Rodríguez Marín, Fátima; González Medina, Sara

    2013-01-01

    En esta comunicación se expone la experiencia de observación sobre el funcionamiento del proyecto Con+ciencia en los cursos de 5º y 6º de Primaria (tercer ciclo) del centro C.E.I.P. “Príncipe de Asturias” (Sevilla) durante el mes de marzo del 2013. Nuestra participación ha buscado conocer en profundidad este proyecto, observar su aplicación real en el aula y sus implicaciones en el alumnado y el profesorado.

  5. Emociones, agencia y experiencia escolar: el papel de los vínculos en los procesos de inclusión escolar en el nivel secundario

    Directory of Open Access Journals (Sweden)

    Mariana Nobile

    2014-04-01

    Full Text Available Desde hace unos años venimos explorando el modo en que la dimensión emocional de la experiencia escolar interviene en los procesos de inclusión-exclusión educativa en el nivelsecundario. Aquí analizamos en profundidad las entrevistas realizadas a 16 jóvenes de sectores populares que han egresado de las llamadas “Escuelas de Reingreso” en las que se indagaron las formas en que ellos enunciaban su experiencia emocional, explorando lasfuentes de dicha emocionalidad. Respeto, entusiasmo y tranquilidad fueron lasformas enunciativas utilizadas para describir sus experiencias. Nuestra hipótesis es que el tipo de vínculos construidos con los docentes en el marco de un formato escolar particular genera una emocionalidad positiva, que permite resignificar la trayectoria escolar personal, reposicionarse frente a la institución escolar y potenciar su sensación de agencia, en términos de sentirse con mayores márgenes de control acerca de su propia vida, permitiéndole de este modo desplegar diferentes tipos de estrategias personales para su integración laboral, educativa y familiar.

  6. Uso de drogas en estudiantes de medicina y su relación con experiencias de maltrato durante la infancia y adolescencia en Uruguay

    Directory of Open Access Journals (Sweden)

    Miguel Pizzanelli

    2015-01-01

    Full Text Available Se evaluó la prevalencia del uso y abuso de sustancias psicoactivas en los estudiantes y su relación con las experiencias adversas durante la infancia y la adolescencia en una investigación de tipo exploratorio, transversal, observacional, basada en el autoreporte de 280 estudiantes universitarios. El consumo reportado de sustancias psicoactivas fue del 72.1%. Las tres sustancias psicoactivas más frecuentemente utilizadas en el último año fueron el alcohol (24.3%, la marihuana (19.3% y el tabaco (16.4%. Un 33.9% de los estudiantes refirieron que sus pares abusaban de sustancias. El maltrato físico y el psicológico fueron las categorías más frecuentemente reportadas. Los estudiantes que afirmaron tener pares que abusaban de sustancias psicoactivas presentaron una probabilidad siete veces mayor de abusar de drogas que el resto de los encuestados. No se encontraron asociaciones estadísticamente significativas (< 0.005 entre el reporte de maltrato en ninguna de sus categorías, y el uso o abuso de drogas.

  7. Incremental value of 99mTc-HYNIC-TOC SPECT/CT over whole-body planar scintigraphy and SPECT in patients with neuroendocrine tumours.

    Science.gov (United States)

    Trogrlic, Mate; Težak, Stanko

    2017-06-12

    The aim of this study was to evaluate the additional value of 99m Tc-HYNIC-TOC SPECT/CT over planar whole-body (WB) scintigraphy and SPECT alone in the detection and accurate localisation of neuroendocrine tumour (NET) lesions. This study included 65 patients with a definitive histological diagnosis of NET prior to scintigraphy. Planar WB scintigraphy, SPECT, and SPECT/CT images were acquired at 4 h post-administration of 670 MBq 99m Tc-HYNIC-TOC. Additional SPECT images at 10 min after tracer administration were also acquired. Clinical and imaging follow-up findings were considered as the reference standards (minimum follow-up period, 15 months). Patient and lesion-based analyses of the efficacies of the imaging modalities were performed. While 38 patients exhibited metastasis of NETs, 27 presented no evidence of metastasis. Upon patient-based analysis, the sensitivity and specificity of SPECT/CT were found to be 88.9 and 79.3 %, respectively. The diagnostic accuracies of WB scintigraphy, 4h-SPECT, and SPECT/CT were 72.3, 73.8, and 84.6 %, respectively. The area under curve (AUC) value for SPECT/CT (0.84) was the highest, followed by those for 4h-SPECT (0.75) and WB scintigraphy (0.74). The accuracy and AUC values of SPECT/CT were significantly better compared to those of WB scintigraphy (p < 0.001), 10 min-SPECT (p < 0.001), and 4 h-SPECT (p = 0.001). The findings of SPECT/CT led to the change in treatment plan of 11 patients (16.9 %). The sensitivity and diagnostic accuracy of SPECT/CT in the evaluation of NET lesions outperforms planar WB imaging or SPECT alone.

  8. The experience of thalassemic adults with their treatment La experiencia de los talasémicos adultos con su tratamiento A experiência dos talassêmicos adultos ao tratamento

    Directory of Open Access Journals (Sweden)

    Marcela Ganzella

    2011-08-01

    Full Text Available This study, based on medical anthropology and oral reports, analyzes the meanings attributed by thalassemic adults to their experiences with the treatment. Interviews were used to collect data, which were analyzed through inductive thematic analysis. Eleven young adults, six of whom were men, at different ages, with different educational levels and occupations participated in the study. The meanings are discussed through the theme "the lives of patients with thalassemia in relation to their treatment". This core meaning highlights the difference made in their identity by having the disease trait, the recognition of the importance of adhering to their treatment, the difficulties in maintaining their social functions, the patients' irregular treatment adherence and their justifications for non-adherence to their treatment. Thalassemic patients conform to their condition and employ a normalization strategy to control the disease and justify irregular treatment adherence.El objetivo de este estudio fue analizar los sentidos dados por los talasémicos adultos a su experiencia con el tratamiento, con base en la antropología médica y en el método del relato oral. Para la recolección de datos usamos entrevistas y seguimos el análisis temático inductivo. Participaron once adultos jóvenes, seis del sexo masculino; con edades, niveles educacionales y profesiones, distintas. Los sentidos da la experiencia son presentados por el tema "La vida del portador de talasemia con el tratamiento". El tema destaca la identidad de ser diferente por: el trazo de la enfermedad, el reconocimiento de la importancia de la adhesión al tratamiento, las dificultades en mantener sus funciones sociales y los episodios de irregularidad en la terapia y sus justificaciones. Aprendimos que los portadores están resignados con su condición y emplean la estrategia de normalización para el control de la enfermedad y para justificar la irregularidad en el tratamiento

  9. Derecho a la movilidad. La experiencia de Bogotá D. C.

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    Fridole Ballén Duque

    2007-01-01

    Full Text Available La movilidad en las grandes urbes se relaciona con la cultura ciudadana. El concepto ha evolucionado de la noción de tráfico o tránsito a la de sistema de movilidad. El “derecho a la mo vilidad” se define, por una parte, en función de los intereses que gobiernan los diferentes desplazamientos de las personas. Además, la movilidad está vinculada a derechos colectivos de gran relevancia en la vida contemporánea como son: medio ambiente, espacio público y accesibilidad universal. Para una mejor comprensión del asunto se aborda la experiencia de Bogotá y se analizan los avances y problemas de la ciudad con respecto al transporte público colectivo tradicional y el sistema de transporte masivo Transmilenio.

  10. RELATO DE EXPERIENCIA PEDAGÓGICAS: " EL USO DE FOTOGRAFIAS AÉREAS VERTICALES EN LA ENSEÑANZA DE CONTENIDOS DE GEOGRAFÍA AGRARIA"

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    Oscar José María Lossio

    2008-12-01

    Full Text Available Las fotografías aéreas verticales son materiales pasibles de ser usados en distintas propuestas didácticas en Geografía, son textos visuales que puede facilitar procesos de conceptualización disciplinar. Se presenta en este trabajo una experiencia pedagógica referida a la enseñanza de contenidos de geografía agraria, incluyendo reflexiones sobre las potencialidades y las limitaciones en el uso de dichas imágenes de representación espacial para el estudio de los espacios agrarios. El relato intenta sistematizar una de las propuestas de enseñanza con apoyo de textos aerofotográficos con los que venimos trabajando desde hace algunos años y corresponde, específicamente, a clases desarrolladas a finales de 2007 en una escuela media de la ciudad de Santa Fe. En trabajo incluye las siguientes cuestiones: en primer lugar, se explicitan los motivos por los cuáles nos motiva relatar una experiencia de uso didáctico de los materiales aerofotográficos; en segundo lugar, se especifican las razones que permiten entender a dichas imágenes como textos visuales; en tercer lugar, se presentan las motivaciones que nos han llevado a seleccionar una secuencia didáctica sobre contenidos de geografía agraria; en cuarto lugar, se aborda la planificación de las clases con relación a las intencionalidades de la propuesta de enseñanza y la contextualización de las mismas dentro del desarrollo del programa; y, en quinto lugar, se presentan e interpretan algunos fragmentos de clase. Se quiere compartir esta experiencia con otros docentes para escuchar sus pareceres y porque consideramos que este relato puede incentivar a otros en el uso de materiales aerofotográficos.

  11. Educar con TIC: desafíos y posibilidades

    Directory of Open Access Journals (Sweden)

    Magalí Daniela Pérez Riedel

    2015-09-01

    Full Text Available En este trabajo se realiza una lectura crítica del libro La aventura de innovar con TIC: aportes conceptuales, experiencias y propuestas, en el que se reflexiona acerca de la incipiente incorporación de las tecnologías de la información y la comunicación en el ámbito de la educación, a la vez que se hacen dialogar distintas prácticas áulicas para vislumbrar las potencialidades y los desafíos que se les presentan hoy a los educadores que trabajan o quieren trabajar con herramientas digitales.

  12. Normal anatomy of lung perfusion SPECT scintigraphy

    International Nuclear Information System (INIS)

    Moskowitz, G.W.; Levy, L.M.

    1987-01-01

    Ten patients studies for possible pulmonary embolic disease had normal lung perfusion planar and SPECT scintigraphy. A computer program was developed to superimpose the CT scans on corresponding SPECT images. Superimposition of CT scans on corresponding SPECT transaxial cross-sectional images, when available, provides the needed definition and relationships of adjacent organs. SPECT transaxial sections provide clear anatomic definition of perfusion defects without foreground and background lung tissue superimposed. The location, shape, and size of the perfusion defects can be readily assessed by SPECT. An algorithm was developed for the differentiation of abnormal pulmonary perfusion patterns from normal structures on variation

  13. Una experiencia de capacitacion-investigacion a docentes coordinadores de pronoei del callao

    Directory of Open Access Journals (Sweden)

    Carmen Coloma

    1992-06-01

    Full Text Available En 1983la Facultad de Educación de la Pontificia Universidad Católica del Perú conjuntamente con la Fundación de Investigaciones Educativas High Scope, inició un Proyecto de Capacitación a personal no profesional en servicio. Esta experiencia piloto que se realizó en 5 programas no escolarizados de Educación Inicial de sectores urbano marginales de Lima y Callao, permitió validar un modelo de capacitación que tiene principios y estrategias muy particulares y cuyos resultados están relacionados con el mejoramiento de la calidad de servicios educativos, el desempeño de animadoras y la participación de la comunidad, lo cual ha propiciado su extensión a otros sectores y niveles.

  14. A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT.

    Science.gov (United States)

    Sciammarella, Maria; Shrestha, Uttam M; Seo, Youngho; Gullberg, Grant T; Botvinick, Elias H

    2017-08-03

    SPECT myocardial perfusion imaging (MPI) is a clinical mainstay that is typically performed with static imaging protocols and visually or semi-quantitatively assessed for perfusion defects based upon the relative intensity of myocardial regions. Dynamic cardiac SPECT presents a new imaging technique based on time-varying information of radiotracer distribution, which permits the evaluation of regional myocardial blood flow (MBF) and coronary flow reserve (CFR). In this work, a preliminary feasibility study was conducted in a small patient sample designed to implement a unique combined static-dynamic single-dose one-day visit imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT for improving the diagnosis of coronary artery disease (CAD). Fifteen patients (11 males, four females, mean age 71 ± 9 years) were enrolled for a combined dynamic and static SPECT (Infinia Hawkeye 4, GE Healthcare) imaging protocol with a single dose of 99m Tc-tetrofosmin administered at rest and a single dose administered at stress in a one-day visit. Out of 15 patients, eleven had selective coronary angiography (SCA), 8 within 6 months and the rest within 24 months of SPECT imaging, without intervening symptoms or interventions. The extent and severity of perfusion defects in each myocardial region was graded visually. Dynamically acquired data were also used to estimate the MBF and CFR. Both visually graded images and estimated CFR were tested against SCA as a reference to evaluate the validity of the methods. Overall, conventional static SPECT was normal in ten patients and abnormal in five patients, dynamic SPECT was normal in 12 patients and abnormal in three patients, and CFR from dynamic SPECT was normal in nine patients and abnormal in six patients. Among those 11 patients with SCA, conventional SPECT was normal in 5, 3 with documented CAD on SCA with an overall accuracy of 64%, sensitivity of 40% and specificity of 83%. Dynamic SPECT image

  15. Imagen y Arte: La Necesidad de la Experiencia por la Sensación

    Directory of Open Access Journals (Sweden)

    Donald Hugh de Barros Kerr Junior (Goy

    2016-02-01

    Full Text Available Muchos procedimientos utilizados en propuestas pedagógicas definen las artes visuales en el cotidiano de escuelas brasileras. Cuestionamos aquellos que, despotencializados, continúan afirmando un carácter meramente instrumental y utilitario del quehacer artístico. Comenzamos la discusión tomando procedimientos que acaban confirmando que la imagen en la escuela, en gran parte, es tratada como ilustración y no como productora de pensamiento. Preguntamos: ¿qué alternativas pueden ser erguidas en el sentido de actualizar el uso de la imagen artística en el salón de clase? ¿Cómo huir de los estereotipos y modelos? Nos fundamentamos en los conceptos de experiencia y de arte como sensación. Con el concepto e heterotopía provocamos la percepción de algo que puede romper la sintaxis y presentarse por la sensación. Defendemos prácticas que hagan funcionar el arte como sensación y no a través de un lenguaje que fija y codifica lo no codificable de la experiencia artística. La sensación puede romper también con una formación docente apegada a rótulos, modelos y modismos. Abriéndonos al no cliché, nuevas formas de pensar y sentir, nos aproximan de los modos de crear propios del arte. Al dar continuidad a estos modos en nuestras vidas, repetimos en la diferencia rompiendo con aquellos procesos tan gobernados y lineales que se empeñan obstinadamente en permanecer en nuestra cotidianidad.

  16. ¿Qué tipo de maestro/a me gustaría ser en el futuro? Mi primera experiencia en un centro escolar innovador

    OpenAIRE

    Rodríguez Marín, Fátima; López Moreno, Francisco; Vázquez Castaño, Virginia; Fernández Arroyo, Jorge

    2013-01-01

    En esta comunicación se presenta la experiencia llevada a cabo como estudiante interna del Departamento de Didáctica de las Ciencias Experimentales y Sociales en colaboración con el CEIP Príncipe de Asturias, en el marco del proyecto Con+Ciencia. Dicho proyecto se puede identificar como innovador, ya que fomenta un aprendizaje por investigación, en el que el alumnado tiene un papel protagonista.

  17. La enseñanza de la matemática a alumnos ciegos y disminuidos visuales. EL relato de una experiencia

    OpenAIRE

    Mántica, Ana María; Götte, Marcela; Dal Maso, María

    2014-01-01

    Se presenta una experiencia realizada con alumnos del profesorado de matemática para trabajar en esta disciplina con alumnos ciegos integrados en escuelas comunes. Los objetivos son mejorar el aprendizaje de la matemática de los alumnos ciegos o disminuidos visuales capacitando a docentes integradores y de matemática, realizando apoyo personalizado a los alumnos ciegos y estudiando y adaptando propuestas didácticas. Se pretende aportar a la formación de los alumnos del profesorado estudiando ...

  18. Conectividad, juego e ignorancia: para acabar de una vez con el profepiola

    OpenAIRE

    Catani, Juan Pablo

    2011-01-01

    El presente trabajo se propone pensar una experiencia de capacitación clínica en la Cátedra de Psicoterapia 2, materia perteneciente al bloque clínico de la Facultad de Psicología, Universidad Nacional de La Plata. Para abordarla, se intentará presentar el interjuego entre la información y la formación, desde el punto de vista de una experiencia que pretende disponer el aula al modo de un juego, con el fin de permitir el devenir de lo clínico dentro de la comisión de trabajos prácticos. ...

  19. Experiencias e interpretaciones en performances rituales (Iruya y El Cajón, noroeste argentino

    Directory of Open Access Journals (Sweden)

    Karen Avenburg

    2014-07-01

    Full Text Available Este artículo se propone reflexionar acerca del modo en que dos performances rituales del noroeste argentino recrean en sus puestas en escena diferentes experiencias. Desde un enfoque etnográfico apoyado en los respectivos trabajos de campo de las autoras, se analizan comparativamente la Fiesta Patronal de la Virgen del Rosario de Iruya (Salta y la Semana Santa de El Cajón (Catamarca. En particular, se discuten algunas de las razones por la cuales en un contexto ritual la puesta en escena implica la recreación de su historia sociocultural y política, mientras que en el otro el eje central transcurre reactualizando eventos cosmológicos. El marco teórico utilizado se basa en el concepto de performance y su relación con la experiencia, siguiendo los aportes realizados por Edward Bruner y Victor Turner.

  20. {sup 99m}Tc-HMPAO Brain SPECT in Seizure Disorder: Comparison Brain SPECT, MRI / CT and EEG

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Hyung In [Kyunghee University Hospital, Seoul (Korea, Republic of); Im, Ju Hyuk; Choi, Chang Woon; Lee, Dong Soo; Chung, June Key; No, Jae Kyu; Lee, Myung Chul; Koh, Chang Soon [Seoul National University Hospital, Seoul (Korea, Republic of)

    1994-03-15

    We studied 115 patients with seizure who had been performed brain SPECT brain MRI of CT and EEG. To evaluate the pattern of brain SPECT in seizure patients 28 of them had secondary epilepsies, 87 had primary epilepsies. In primary epilepsies, 42 were generalized seizure and 45 were partial seizure. The causes of secondary epilepsies were congenital malformation, cerebromalacia, cerebral infarction ultiple sclerosis, AV-malformation. granuloma and etc, in order. In 28 secondary epilepsies, 25 of them, brain SPECT lesions was concordant with MRI or CT lesions. 3 were disconcordant. The brain SPECT findings of generalized seizure were normal in 22 patients, diffuse irregular decreased perfusion in 8, decreased in frontal cortex in 4. temporal in 5 and frontotemporal in 3. In 45 partial seizure, 19 brain SPECT were concordant with EEG (42.4%).

  1. Time course evaluation of myocardial perfusion after reperfusion therapy by 99mTc-tetrofosmin SPECT in patients with acute myocardial infarction.

    Science.gov (United States)

    Tanaka, R; Nakamura, T

    2001-09-01

    Myocardial perfusion imaging with 99mTc-labeled agents immediately after reperfusion therapy can underestimate myocardial salvage. It is also conceivable that delayed imaging is useful for assessing the risk area. However, to our knowledge, very few studies have sequentially evaluated these image changes. We conducted 99mTc-tetrofosmin (TF) and 123I-beta-methyl-p-iodophenylpentadecanoic acid (BMIPP) SPECT before and after reperfusion to treat acute myocardial infarction and quantified changes in TF myocardial accumulation and reverse redistribution. Seventeen patients with a first myocardial infarction underwent successful reperfusion. We examined SPECT images obtained at the onset (preimage), those acquired 30 min (early image) and 6 h (delayed image) after TF injection, and images acquired 1, 4, 7, and 20 d after reperfusion (post-1-d, post-4-d, post-7-d, and post-20-d image, respectively). We also examined BMIPP SPECT images after 7 +/- 1.8 d (BMIPP image). Polar maps were divided into 48 segments to calculate percentage uptake, and time course changes in segment numbers below 60% were observed as abnormal area. Moreover, cardiac function was analyzed by gated TF SPECT on 1 and 20 d after reperfusion. In reference to the abnormal area on the early images, the post-1-d image was significantly improved compared with the preimage (P < 0.01) as was the post-7-d image compared with the post-1-d and post-4-d images (P < 0.05, respectively). However, post-20-d and post-7-d images did not significantly differ. Therefore, the improvement in myocardial accumulation reached a plateau 7 d after reperfusion. On the other hand, the abnormal area on the delayed images was significantly greater (P < 0.01) compared with that on the early images from 4 to 20 d after reperfusion, as the value was essentially constant. The correlations of the abnormal area between the preimage and the post-7-d delayed image, the preimage and the BMIPP image, and the post-7-d delayed image and the

  2. VIOLENCIA URBANA Y SUBJETIVIDADES VICTIMIZANTES: SENTIDOS Y EXPERIENCIAS ORGANIZATIVAS DE LAS VÍCTIMAS DE LA INSEGURIDAD EN ARGENTINA

    Directory of Open Access Journals (Sweden)

    Mercedes Celina Calzado

    2014-01-01

    Full Text Available La violencia urbana introduce en América Latina modalidades de narrar las experiencias de victimización. En las sociedades de seguridad se reconfiguran las subjetividades y se redefinen discursos y prácticas políticas individuales y colectivas. Este artículo reflexiona acerca de los modos en que se constituyen los discursos de los grupos organizados de víctimas de la inseguridad en Argentina ¿La experiencia individual define la subjetividad? ¿Ser familiar de una víctima fatal (o no de la criminalidad establece los parámetros desde los cuales se explica la experiencia? ¿O se ordena a partir de definiciones previas de verdad, conceptos preexistentes que nominalizan el sufrimiento? Desde un conjunto de entrevistas realizadas a familiares de víctimas de la inseguridad, se reflexiona sobre las experiencias que originan un sujeto colectivo atravesado por la violencia urbana. Esta investigación propone una tipología con cinco clases de vocabularios de intervención de los grupos organizados de víctimas de la inseguridad: colectivos tópicos, colectivos categóricos, colectivos de cercanías, colectivos “manzaneros” y colectivos mínimos.

  3. Quantitation of myocardial blood flow and myocardial flow reserve with {sup 99m}Tc-sestamibi dynamic SPECT/CT to enhance detection of coronary artery disease

    Energy Technology Data Exchange (ETDEWEB)

    Hsu, Bailing [University of Missouri-Columbia, Nuclear Science and Engineering Institute, Columbia, MO (United States); Chen, Fu-Chung; Chen, Chien-Cheng [Show Chwan Memorial Hospital, Section of Cardiology, Department of Internal Medicine, Changhua (China); Wu, Tao-Cheng [Taipei Veterans General Hospital, Section of Cardiology, Department of Internal Medicine, Taipei (China); Huang, Wen-Sheng [Changhua Christian Hospital, Department of Medical Research and Department of Nuclear Medicine, Changhua (China); Hou, Po-Nien [Chang Bing Show Chwan Memorial Hospital, Department of Nuclear Medicine, Lukong Town, Changhua Shien (China); Hung, Guang-Uei [Chang Bing Show Chwan Memorial Hospital, Department of Nuclear Medicine, Lukong Town, Changhua Shien (China); Central Taiwan University of Science and Technology, Department of Medical Imaging and Radiological Science, Taichung (China); China Medical University, Department of Biomedical Imaging and Radiological Science, Taichung (China)

    2014-12-15

    Conventional dual-head single photon emission computed tomography (SPECT)/CT systems capable of fast dynamic SPECT (DySPECT) imaging have a potential for flow quantitation. This study introduced a new method to quantify myocardial blood flow (MBF) and myocardial flow reserve (MFR) with DySPECT scan and evaluated the diagnostic performance of detecting coronary artery disease (CAD) compared with perfusion using invasive coronary angiography (CAG) as the reference standard. This study included 21 patients with suspected or known CAD who had received DySPECT, ECG-gated SPECT (GSPECT), and CAG (13 with ≥50 % stenosis in any vessel; non-CAD group: 8 with patent arteries or <50 % stenosis). DySPECT and GSPECT scans were performed on a widely used dual-head SPECT/CT scanner. The DySPECT imaging protocol utilized 12-min multiple back-and-forth gantry rotations during injections of {sup 99m}Tc-sestamibi (MIBI) tracer at rest or dipyridamole-stress stages. DySPECT images were reconstructed with full physical corrections and converted to the physical unit of becquerels per milliliter. Stress MBF (SMBF), rest MBF (RMBF), and MFR were quantified by a one-tissue compartment flow model using time-activity curves derived from DySPECT images. Perfusion images were processed for GSPECT scan and interpreted to obtain summed stress score (SSS) and summed difference score (SDS). Receiver-operating characteristic (ROC) analyses were conducted to evaluate the diagnostic performance of flow and perfusion. Using the criteria of ≥50 % stenosis as positive CAD, areas under the ROC curve (AUCs) of flow assessment were overall significantly greater than those of perfusion. For patient-based analysis, AUCs for MFR, SMBF, SSS, and SDS were 0.91 ± 0.07, 0.86 ± 0.09, 0.64 ± 0.12, and 0.59 ± 0.13. For vessel-based analysis, AUCs for MFR, SMBF, SSS, and SDS were 0.81 ± 0.05, 0.76 ± 0.06, 0.62 ± 0.07, and 0.56 ± 0.08, respectively. The preliminary data suggest that MBF quantitation with a

  4. La experiencia docente en un MOOC

    OpenAIRE

    Ramírez Montoya, María Soledad

    2013-01-01

    1. Objetivo de la conferencia; 2. Antecedentes de experiencias de cursos masivos; 3. Experiencia en un curso MOOC-Proyecto SINED-CLARISE para la educación a distancia; 4. Preparación para un curso MOOC en Coursera

  5. Las TIC en la Escuela de Enfermería de la Universidad del Valle: Una experiencia transformadora

    OpenAIRE

    Melva Patricia Ocampo; Luz Ángela Argote; María Clara Tovar

    2011-01-01

    Introducción: Con el fin de difundir la experiencia de la Escuela de Enfermería en el uso de estrategias innovadoras que facilitan la formación de los estudiantes en la educación superior con difícil acceso a la educación presencial por cumplir diversos roles en la sociedad, se presenta el siguiente artículo donde se  sistematiza  esta estrategia, haciendo un recorrido a partir de la década de 1960 hasta el uso de las Tecnologías de la Información y las Comunicaciones (TIC) en la actualidad.M...

  6. Cuando la alegría entra al centro de salud: una experiencia de promoción de salud en Buenos Aires, Argentína

    Directory of Open Access Journals (Sweden)

    Claudia Bang

    2016-06-01

    Full Text Available Como parte de una investigación posdoctoral, el presente trabajo describe y analiza una experiencia de promoción y educación para la salud integral desarrollada por un Centro de Salud y Acción Comunitaria en una zona marginal urbana del sur de la Ciudad de Buenos Aires. Se trata de un estudio exploratorio-descriptivo que utiliza técnicas cualitativas para el trabajo de campo y análisis del material. En articulación con las dimensiones de la APS integral, se describe y analiza un dispositivo vincular, centrado en la interdisciplina y la articulación intersectorial como elementos clave de la organización de los cuidados en salud, con la inclusión de la dimensión intercultural y la participación comunitaria. Se incorporan actividades de promoción de salud integral centradas en el arte, creatividad y juego, constituyéndose en una experiencia resistencial al modelo biomédico de atención, con fuerte impacto subjetivo en los profesionales y la comunidad participante.

  7. El restablecimiento socioeconómico de la población en condiciones de desplazamiento. Bucaramanga, una experiencia de dignidad humana en medio del conflicto

    Directory of Open Access Journals (Sweden)

    Jorge Castellamos Pulido

    2013-07-01

    Full Text Available Este documento presenta un análisis de la experiencia de restablecimiento socioeconómico de población desplazada por el conflicto armado, ubicada en el Área Metropolitana de Bucaramanga. Se destaca la ejecución de una estrategia de un modelo individual de asesoría, acompañamiento y aplacamiento financiero para establecer negocios, a partir del talento humano y la dotación de capacidades para auto-gestión de 200 desplazados y sus familias. Se describe la experiencia de la Corporación Compromiso entre el año 2001 y el 2005, con aprendizajes de trabajo en alianza con la Organización Internacional de Migraciones OIM, la Red de Solidaridad Social, el Fondo de Desarrollo Tecnológico para la Pequeña y Mediana Empresa FOMPYME y CORFAS, con instituciones públicas y privadas, cofinanciadoras de un fondo de micro crédito y micro-finan-ciamiento, mediante el desarrollo de un programa de desarrollo social.

  8. Clinical evaluation of SPECT in cerebrovascular disease

    International Nuclear Information System (INIS)

    Oshibuchi, Masao; Satoh, Mitsutaka; Kanda, Tetsuro; Nishi, Fumiaki; Yamane, Kanji; Fujimatsu, Masahiko; Edamitsu, Satoshi; Anno, Yasuro; Ohtake, Hisashi.

    1989-01-01

    In 131 patients with cerebrovascular disease, regional cerebral blood flow were determined by 123 I-IMP (N-isopropyl ( 123 I)-iodoamphetamine) or 99m Tc-HM-PAO ( 99m Tc (d, 1)-hexamethyl propyleneamine oxime) SPECT and findings were compared with those of X-CT or MRI. The perfusion deficit detected by SPECT was larger than the deficit by X-CT or MRI in every case. The perfusion deficit area was more clearly demonstrated by SPECT than by X-CT or MRI in patients with acute cerebral infarction. The hypoperfusion area determined by 123 I-IMP SPECT was wider than that by 99m Tc-HM-PAO SPECT. The crossed cerebellar diaschisis was observed in 56 out of 131 cases (43%). The results of operation were quantitatively evaluated by 123 I-IMP SPECT in 25 patients. (author)

  9. El reconocimiento y la acreditación de la experiencia

    Directory of Open Access Journals (Sweden)

    Óscar MEDINA FERNÁNDEZ

    2010-07-01

    Full Text Available Según los datos de la Encuesta de Población Activa del 2006, el 44,3% de la población ocupada española carece de formación relacionada con el trabajo. Como sucede prácticamente en todos los países desarrollados, se trata de unos trabajadores que no han podido estudiar en su momento y se han puesto a trabajar desde muy jóvenes y es precisamente en el puesto de trabajo donde han aprendido lo que saben y ponen al servicio de la producción. Dicho de otra manera, son trabajadores que han adquirido las competencias propias de una titulación profesional, pero no tienen el título correspondiente. Los sistemas de acreditación de la experiencia tratan de hacer justicia con estos trabajadores, reconociendo y certificando que mediante sistemas no formales o informales de educación han podido adquirir las competencias propias de una titulación. Presentamos en este artículo parte de los resultados de un trabajo de investigación sobre Sistemas de Acreditación: en primer lugar abordamos el concepto de competencia y el de evaluación de la competencia; a continuación hacemos una reseña sobre la metodología, los documentos o protocolos que se emplean en los sistemas de acreditación y las fases a seguir; finalmente entramos en el modo en que estos sistemas de acreditación de la experiencia se están planteando a nivel internacional y en España.

  10. Análisis de la evolución en la concepción de la discapacidad en las experiencias inclusivas de gestión para estudiantes con discapacidad física en la educación superior

    OpenAIRE

    Huaman Huriarte, Roxana

    2015-01-01

    El estudio que se presenta es una investigación documental con enfoque cualitativo, de carácter exploratorio, y de tipo documental bibliográfico. Tiene como objetivos presentar las experiencias inclusivas de discapacidad física en instituciones de educación superior encontradas en artículos publicados entre el año 2000 y 2013 en revistas académicas, y analizar la evolución en la concepción social de la discapacidad. Para tal fin, se ha categorizado las prácticas encontradas en tres de las...

  11. EXPERIENCIAS CONSTRUCTIVAS DEL TERREMOTO DE LORCA

    Directory of Open Access Journals (Sweden)

    José-Carlos Salcedo Hernández

    2012-01-01

    Full Text Available El terremoto de Lorca del 11 de mayo de 2011 es el más importante que ha sufrido el territorio peninsular español en los últimos 55 años, desde el terremoto de Albolote (Granada de 1956 que, casualmente, fue del mismo tipo y tuvo idéntica magnitud de 5,1 grados en la escala Richter. En estos 55 años, la tipología de los edificios ha cambiado completamente, pasando de edificios de muros de fábrica de hasta dos plantas de altura, a la generalización de edificios de pisos de una media de 6 plantas, de pilares y vigas con nudos rígidos y forjados de hormigón. Es importante extraer experiencias constructivas del comportamiento que han tenido los edificios de Lorca, porque es el único caso real de que disponemos, para la mejora de la seguridad estructural antisísmica de los edificios en España. En Lorca se ha constatado el mal comportamiento de las estructuras de fábrica de ladrillo con las que está construido el patrimonio histórico. Se ha probado que, con la sola excepción de un edificio, las estructuras nuevas de hormigón y acero han superado una aceleración sísmica del triple de la prevista por la norma sismorresistente NCSE-02, con la que fueron calculadas. Por el contrario, se ha constatado un pésimo comportamiento de los elementos de fábrica (petos, cerramientos, tabiques, etc, de ladrillo con fracasos generalizados, que son los que produjeron los enormes daños materiales en las viviendas y los daños personales. Estos elementos no son «estructurales», pero la norma NCSE-02 establecía para ellos unas condiciones que no debieron aplicarse en las construcciones realizadas desde su implantación.

  12. AUTOAPRENDIZAJE DE ÉTICA EN HISTORIA DE LA MEDICINA. UNA EXPERIENCIA ATRACTIVA

    OpenAIRE

    José Jara Rascon

    2014-01-01

    Introducción. El concepto de Medicina basada en la persona puede ser transmitido desde los estudios de pregrado. La asignatura de Historia de la Medicina puede ser un buen lugar para ello si se involucra al alumnado confrontándole con los protagonistas y las acciones que dieron lugar a diferentes avances científicos. Material y Método. En este trabajo se muestra la experiencia metodológica de la transmisión de conocimientos de Historia de la Medicina siguiendo un modelo de enseñanza compartid...

  13. A multidisciplinary approach to scaling up HIV/AIDS treatment and care: the experience of the Bahamas Enfoque multidisciplinario para ampliar el tratamiento y la atención de pacientes con infección por VIH y sida: la experiencia de las Bahamas

    Directory of Open Access Journals (Sweden)

    James Fitzgerald

    2005-01-01

    Full Text Available Las Bahamas han estado poniendo en práctica un proceso de ampliación intensivo, práctico e integrado que ha provocado un rápido aumento del número de personas con infección por VIH o sida que tienen acceso al tratamiento con antirretrovíricos y a la atención de salud. Este proceso de rápida ampliación se ha visto facilitado por el establecimiento de un equipo multidisciplinario con gran experiencia en ciertas áreas clave, por la creación de una metodología para identificar carencias en los servicios de salud, y por la adopción de un plan que aprovecha los recursos existentes y los logros obtenidos en el pasado. Sigue habiendo la necesidad de preparar recursos humanos con la capacidad para responder a las exigencias del proceso de ampliación, así como de identificar nuevas fuentes de financiamiento para garantizar su sustentabilidad.

  14. Functional neuroimaging in epilepsy: FDG-PET and SPECT

    International Nuclear Information System (INIS)

    Lee, Sang Kun; Lee, Dong Soo

    2003-01-01

    Finding epileptogenic zone is the most important step for the successful epilepsy surgery. F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and single photon emission computed tomography (SPECT) can be used in the localization of epileptogenic foci. In medial temporal lobe epilepsy, the diagnostic sensitivity of FDG-PET and ictal SPECT is excellent. However, detection of hippocampal sclerosis by MRI is so certain that use of FDG-PET and ictal SPECT in medial temporal lobe epilepsy is limited for some occasions. In neocortical epilepsy, the sensitivities of FDG-PET or ictal SPECT are fair. However, FDG-PET and ictal SPECT can have a crucial role in the localization of epileptogenic foci for non-lesional neocortical epilepsy. Interpretation of FDG-PET has been recently advanced by voxel-based analysis and automatic volume of interest analysis based on a population template. Both analytical methods can aid the objective diagnosis of epileptogenic foci. lctal SPECT was analyzed using subtraction methods and voxel-based analysis. Rapidity of injection of tracers, ictal EEG findings during injection of tracer, and repeated ictal SPECT were important technical issues of ictal SPECT. SPECT can also be used in the evaluation of validity of Wada test

  15. Functional neuroimaging in epilepsy: FDG-PET and SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Kun; Lee, Dong Soo [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2003-02-01

    Finding epileptogenic zone is the most important step for the successful epilepsy surgery. F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and single photon emission computed tomography (SPECT) can be used in the localization of epileptogenic foci. In medial temporal lobe epilepsy, the diagnostic sensitivity of FDG-PET and ictal SPECT is excellent. However, detection of hippocampal sclerosis by MRI is so certain that use of FDG-PET and ictal SPECT in medial temporal lobe epilepsy is limited for some occasions. In neocortical epilepsy, the sensitivities of FDG-PET or ictal SPECT are fair. However, FDG-PET and ictal SPECT can have a crucial role in the localization of epileptogenic foci for non-lesional neocortical epilepsy. Interpretation of FDG-PET has been recently advanced by voxel-based analysis and automatic volume of interest analysis based on a population template. Both analytical methods can aid the objective diagnosis of epileptogenic foci. lctal SPECT was analyzed using subtraction methods and voxel-based analysis. Rapidity of injection of tracers, ictal EEG findings during injection of tracer, and repeated ictal SPECT were important technical issues of ictal SPECT. SPECT can also be used in the evaluation of validity of Wada test.

  16. Procesamiento traumatogénico del abuso sexual infantil en niñas y su relación con variables victimológicas

    Directory of Open Access Journals (Sweden)

    Hugo Eduardo Plaza Villarroel

    2014-11-01

    Full Text Available Se indaga la relación entre el procesamiento traumatogénico de experiencias de violencia sexual en niñas, con bcaracterísticas de la victimización sufrida. Una muestra de 40 niñas víctimas de violencia sexual respondió una escala de sentimientos de estigmatización, indefensión, traición y culpa, mientras que el profesional tratante completó una ficha sociodemográfica con datos de la vulneración ocurrida. Los resultados sugieren que; abusos más intrusivos, crónicos, con empleo de fuerza e intrafamiliares se relacionan con mayores puntajes en los sentimientos de estigmatización, indefensión, traición y culpa. Adicionalmente, la edad de la víctima y el apoyo familiar ante la develación arrojaron correlaciones con el procesamiento traumatogénico de experiencias de violencia sexual.

  17. A methodology for generating normal and pathological brain perfusion SPECT images for evaluation of MRI/SPECT fusion methods: application in epilepsy

    Energy Technology Data Exchange (ETDEWEB)

    Grova, C [Laboratoire IDM, Faculte de Medecine, Universite de Rennes 1, Rennes (France); Jannin, P [Laboratoire IDM, Faculte de Medecine, Universite de Rennes 1, Rennes (France); Biraben, A [Laboratoire IDM, Faculte de Medecine, Universite de Rennes 1, Rennes (France); Buvat, I [INSERM U494, CHU Pitie Salpetriere, Paris (France); Benali, H [INSERM U494, CHU Pitie Salpetriere, Paris (France); Bernard, A M [Service de Medecine Nucleaire, Centre Eugene Marquis, Rennes (France); Scarabin, J M [Laboratoire IDM, Faculte de Medecine, Universite de Rennes 1, Rennes (France); Gibaud, B [Laboratoire IDM, Faculte de Medecine, Universite de Rennes 1, Rennes (France)

    2003-12-21

    Quantitative evaluation of brain MRI/SPECT fusion methods for normal and in particular pathological datasets is difficult, due to the frequent lack of relevant ground truth. We propose a methodology to generate MRI and SPECT datasets dedicated to the evaluation of MRI/SPECT fusion methods and illustrate the method when dealing with ictal SPECT. The method consists in generating normal or pathological SPECT data perfectly aligned with a high-resolution 3D T1-weighted MRI using realistic Monte Carlo simulations that closely reproduce the response of a SPECT imaging system. Anatomical input data for the SPECT simulations are obtained from this 3D T1-weighted MRI, while functional input data result from an inter-individual analysis of anatomically standardized SPECT data. The method makes it possible to control the 'brain perfusion' function by proposing a theoretical model of brain perfusion from measurements performed on real SPECT images. Our method provides an absolute gold standard for assessing MRI/SPECT registration method accuracy since, by construction, the SPECT data are perfectly registered with the MRI data. The proposed methodology has been applied to create a theoretical model of normal brain perfusion and ictal brain perfusion characteristic of mesial temporal lobe epilepsy. To approach realistic and unbiased perfusion models, real SPECT data were corrected for uniform attenuation, scatter and partial volume effect. An anatomic standardization was used to account for anatomic variability between subjects. Realistic simulations of normal and ictal SPECT deduced from these perfusion models are presented. The comparison of real and simulated SPECT images showed relative differences in regional activity concentration of less than 20% in most anatomical structures, for both normal and ictal data, suggesting realistic models of perfusion distributions for evaluation purposes. Inter-hemispheric asymmetry coefficients measured on simulated data were

  18. Quantitation of myocardial blood flow and myocardial flow reserve with 99mTc-sestamibi dynamic SPECT/CT to enhance detection of coronary artery disease

    International Nuclear Information System (INIS)

    Hsu, Bailing; Chen, Fu-Chung; Chen, Chien-Cheng; Wu, Tao-Cheng; Huang, Wen-Sheng; Hou, Po-Nien; Hung, Guang-Uei

    2014-01-01

    Conventional dual-head single photon emission computed tomography (SPECT)/CT systems capable of fast dynamic SPECT (DySPECT) imaging have a potential for flow quantitation. This study introduced a new method to quantify myocardial blood flow (MBF) and myocardial flow reserve (MFR) with DySPECT scan and evaluated the diagnostic performance of detecting coronary artery disease (CAD) compared with perfusion using invasive coronary angiography (CAG) as the reference standard. This study included 21 patients with suspected or known CAD who had received DySPECT, ECG-gated SPECT (GSPECT), and CAG (13 with ≥50 % stenosis in any vessel; non-CAD group: 8 with patent arteries or 99m Tc-sestamibi (MIBI) tracer at rest or dipyridamole-stress stages. DySPECT images were reconstructed with full physical corrections and converted to the physical unit of becquerels per milliliter. Stress MBF (SMBF), rest MBF (RMBF), and MFR were quantified by a one-tissue compartment flow model using time-activity curves derived from DySPECT images. Perfusion images were processed for GSPECT scan and interpreted to obtain summed stress score (SSS) and summed difference score (SDS). Receiver-operating characteristic (ROC) analyses were conducted to evaluate the diagnostic performance of flow and perfusion. Using the criteria of ≥50 % stenosis as positive CAD, areas under the ROC curve (AUCs) of flow assessment were overall significantly greater than those of perfusion. For patient-based analysis, AUCs for MFR, SMBF, SSS, and SDS were 0.91 ± 0.07, 0.86 ± 0.09, 0.64 ± 0.12, and 0.59 ± 0.13. For vessel-based analysis, AUCs for MFR, SMBF, SSS, and SDS were 0.81 ± 0.05, 0.76 ± 0.06, 0.62 ± 0.07, and 0.56 ± 0.08, respectively. The preliminary data suggest that MBF quantitation with a conventional SPECT/CT system and the flow quantitation method is a clinically effective approach to enhance CAD detection. (orig.)

  19. Virtualización de las ecuaciones diferenciales: Una experiencia nueva.

    Directory of Open Access Journals (Sweden)

    Guerrero Manzano, Mª del Mar

    2004-01-01

    Full Text Available En estos últimos años venimos asistiendo a una gran proliferación del uso de las nuevas tecnologías en la enseñanza universitaria. Teniendo en cuenta que su utilización no es fácil, pero que hoy es una realidad en la Universidad, y cada vez con mayor importancia, un grupo de profesores nos hemos planteado cómo virtualizar una parte de la materia que normalmente impartimos con la asignatura de Matemáticas en los estudios de Economía y Empresa. Las peculiaridades de esta asignatura y las características propias, la hacen especialmente complicada en la enseñanza presencial, por ello parece lógico que nos apoyemos en la enseñanza virtual de la misma. La opción escogida ha sido la de impartir la parte de dinámica económica (Ecuaciones Diferenciales de nuestra asignatura♣ en un campus virtual, compartido entre nueve universidades españolas (Grupo 9 de Universidades. Se van a poner de manifiesto los resultados de nuestra experiencia, indicando tanto las ventajas como los inconvenientes con los que nos hemos encontrado.

  20. Arte de recreo: La experiencia plástica como medio educativo

    OpenAIRE

    Álvarez Romero, María

    2016-01-01

    Este proyecto propone defender un arte colectivo que funcione en su plenitud con la colaboración del público. Hace uso del factor procesual y relacional para acercarlo a las personas que no tienen noción del arte contemporáneo. Propone hacer partícipe al espectador de la creación plástica y otorgar más importancia a la experiencia que adquieran que a su resultado final. Tenemos la intención de reencantar el arte a través de la atracción, la estética y el juego. Buscamos influir...

  1. Experiencias en la intervención psicológica con familias de personas dependientes

    OpenAIRE

    Ortiz Muñoz, María Dolores

    2007-01-01

    La atención e intervención con familias es fundamental para realizar programas de intervención eficaces con personas dependientes. Entre otras disciplinas, la psicología y sus profesionales han realizado numerosas contribuciones a nivel teórico y y práctico con este colectivo. Existen numerosas necesidades de atención y programas de intervención psicológicos con familiares cuidadores. En este artículo se presenta un ejemplo de intervención con familiares de personas mayores dependientes. T...

  2. Una experiencia didáctica con el collage.

    Directory of Open Access Journals (Sweden)

    Joaquim Cantalozella Planas

    2008-07-01

    Full Text Available El punto de partida que Joan Miró estableció para realizar las dieciocho Pintures segons collage de 1933 nos sirven hoy para hacer una propuesta que permita pensar en algunas de las claves de la pintura contemporánea. Términos como la apropiación, la autoría o la subjetividad del artista se ponen en juego cuando se activa el dispositivo del collage como modelo. Aquí se plantea una actividad de aprendizaje que confronta el trabajo individual con el colectivo y que tiene como objetivo principal la reflexión sobre el lenguaje pictórico.

  3. Un acercamiento a la(s experiencia(s infantil(es en relación al habitar y comer en contextos de socio-segregación urbana

    Directory of Open Access Journals (Sweden)

    Ileana Desirée Ibáñez

    2016-06-01

    Full Text Available El presente trabajo, tiene por objetivo abordar las dinámicas conflictuales relacionadas con la experiencia urbana de niños y niñas de las clases subalternas a partir de reordenamientos espaciales/corporales generados por políticas públicas, en este caso dos programas del Gobierno de la provincia de Córdoba, Argentina: Programa Asistencia Integral Córdoba (PAICor y Programa “Mi casa, Mi vida”. En esa dirección aquí analizaremos la conflictividad latente en relación al espacio, circulación y acceso a la alimentación a partir de algunas vivencias cotidianas de niños/as y sus grupos familiares a partir de su doble condición: comensales del PAICor y pobladores de las ciudades-barrio. Para ello se realizaron observaciones, entrevistas etnográficas y talleres expresivos creativos con madres y niños/as habitantes de las mismas.

  4. SP-ECT imaging and its physical study

    International Nuclear Information System (INIS)

    Kinoshita, Fujimi

    1983-01-01

    Recently, more than a hundred hospitals are provided with SPECT system for clinical examination in Japan. However, a standardization of measuring method and performance test of the systems is ont yet made. We have been studying some basic problems of SPECT system with special phantoms originaly designed by ourselves. We got a conclusion that a standardized phantom is necessary for comparing performances between SPECT systems. In clinical experiences with 3,332 cases, we think that SPECT image combined with conventional image presents much more informations for accurate diagnosis, especially in brain, bone and tumor imagings. Synthesized image of SPECT and XCT, double tracer image and transmission image are useful to visualize the body contour and the clinical diagnosis. (author)

  5. Evaluación de una experiencia significativa en el diseño curricular de un curso de inglés específico con énfasis en TIC

    Directory of Open Access Journals (Sweden)

    Keiby Caro Oviedo

    2015-10-01

    Full Text Available Este artículo da cuenta de la evaluación de una experiencia significativa en el diseño curricular de un curso de inglés específico con énfasis en TIC (Tecnologías de la Información y la Comunicación nivel 1, ofrecido por el Centro de Idiomas de la Universidad Simón Bolívar a los estudiantes del programa de Ingeniería de Sistemas durante el segundo semestre de 2011. AbstractThis article reports on the evaluation of significant experience in curriculum design of a specific English course with emphasis on ICT (Information and Communication Technologies Level 1, offered by the Language Centre of the University Simon Bolivar students of Systems Engineering program during the second semester of 2011.

  6. Motor activation SPECT for the neurosurgical diseases. Clinical application

    International Nuclear Information System (INIS)

    Noguchi, Hiroshi; Kawaguchi, Shoichiro; Sakaki, Toshisuke; Imai, Teruhiko; Ohishi, Hajime

    1999-01-01

    We evaluated and analyzed the motor activation single photon emission computed tomography (M-SPECT) findings on patients with ischemic cerebrovascular diseases (CVD). The M-SPECT studies were carried out on 91 patients with ischemic cerebrovascular diseases. The M-SPECT study was performed using the finger opposition task in each case. The SPECT images were superimposed on the magnetic resonance images (MRIs) for each case using Image Fusion Software. The result of the M-SPECT was expressed as positive or negative. The cases with a marked increase of blood flow in the sensorio-motor cortex after the finger opposition task were categorized as positive, and those cases showing no marked increase of blood flow were categorized as negative. Among the 91 cases examined, 53 (58%) were categorized as positive in the M-SPECT study. Among the negative M-SPECT cases treated with revascularization surgery, there were some cases showing positive M-SPECT results postoperatively. The cases without any revascularization surgery did not change the M-SPECT findings in each during the follow-up period. The M-SPECT procedure for examining intracranial lesions could provide the cortical localization of the motor function. The M-SPECT procedure in the ischemic CVDs contributes to knowledge about the choices of treatment and the evaluation of the treatment result. (author)

  7. Motor activation SPECT for the neurosurgical diseases. Clinical application

    Energy Technology Data Exchange (ETDEWEB)

    Noguchi, Hiroshi; Kawaguchi, Shoichiro; Sakaki, Toshisuke; Imai, Teruhiko; Ohishi, Hajime [Nara Medical Univ., Kashihara (Japan)

    1999-08-01

    We evaluated and analyzed the motor activation single photon emission computed tomography (M-SPECT) findings on patients with ischemic cerebrovascular diseases (CVD). The M-SPECT studies were carried out on 91 patients with ischemic cerebrovascular diseases. The M-SPECT study was performed using the finger opposition task in each case. The SPECT images were superimposed on the magnetic resonance images (MRIs) for each case using Image Fusion Software. The result of the M-SPECT was expressed as positive or negative. The cases with a marked increase of blood flow in the sensorio-motor cortex after the finger opposition task were categorized as positive, and those cases showing no marked increase of blood flow were categorized as negative. Among the 91 cases examined, 53 (58%) were categorized as positive in the M-SPECT study. Among the negative M-SPECT cases treated with revascularization surgery, there were some cases showing positive M-SPECT results postoperatively. The cases without any revascularization surgery did not change the M-SPECT findings in each during the follow-up period. The M-SPECT procedure for examining intracranial lesions could provide the cortical localization of the motor function. The M-SPECT procedure in the ischemic CVDs contributes to knowledge about the choices of treatment and the evaluation of the treatment result. (author)

  8. Creando y compartiendo conocimiento con herramientas 2.0 : una experiencia sobre las prácticas del grado en educación infantil en entornos de aprendizaje colaborativo

    Directory of Open Access Journals (Sweden)

    Raúl Santiago Campión

    2013-05-01

    Full Text Available El aprendizaje on-line es ya una realidad habitual en el mundo de la educación y, específicamente, en el de la educación superior. En este artículo se ofrece una experiencia real de aplicación de algunas herramientas de la web 2.0 en el contexto de la asignatura de Prácticas de Orientación Familiar y Escolar en el Grado en Educación Infantil. Se aportan los modelos de planteamiento de las diferentes actividades y la descripción de las tareas realizadas, así como los resultados sobre el grado de satisfacción de los alumnos obtenidos a través de encuestas on-line, llevando a cabo una comparación con los métodos tradicionales utilizados por la mayoría de las materias cursadas.

  9. Violencia urbana y subjetividades victimizantes: sentidos y experiencias organizativas de las víctimas de la inseguridad en Argentina

    Directory of Open Access Journals (Sweden)

    Mercedes Celina Calzado

    2014-09-01

    Full Text Available La violencia urbana introduce en América Latina modalidades de narrar las experiencias de victimización. En las sociedades de seguridad se reconfiguran las subjetividades y se redefinen discursos y prácticas políticas individuales y colectivas. Este artículo reflexiona acerca de los modos en que se constituyen los discursos de los grupos organizados de víctimas de la inseguridad en Argentina ¿La experiencia individual define la subjetividad? ¿Ser familiar de una víctima fatal (o no de la criminalidad establece los parámetros desde los cuales se explica la experiencia? ¿O se ordena a partir de definiciones previas de verdad, conceptos preexistentes que nominalizan el sufrimiento? Desde un conjunto de entrevistas realizadas a familiares de víctimas de la inseguridad, se reflexiona sobre las experiencias que originan un sujeto colectivo atravesado por la violencia urbana. Esta investigación propone una tipología con cinco clases de vocabularios de intervención de los grupos organizados de víctimas de la inseguridad: colectivos tópicos, colectivos categóricos, colectivos de cercanías, colectivos “manzaneros” y colectivos mínimos.

  10. Curso híbrido y de aula invertida apoyado en MOOC: experiencia de autoevaluación

    Directory of Open Access Journals (Sweden)

    Patricia Salinas Martínez

    2015-04-01

    Full Text Available Este escrito comparte elementos sobre el diseño e implementación del curso híbrido y aula invertida de “Introducción a las matemáticas universitarias”, apoyado en el curso MOOC “Matemáticas y movimiento” en Coursera. La experiencia se realizó en el segundo semestre de 2013 con ocho grupos escolares en una universidad prestigiosa del norte de México. El trabajo fuera del aula y en línea incluye el estudio de videos en preparación para las actividades presenciales en aula, en las que se profundiza en el aprendizaje que los videos promueven. La experiencia considera el trabajo colegiado entre los profesores durante el cual fueron tomadas decisiones a favor de indagar de manera sistemática las bondades de este tipo de formato innovador para el curso. Un estudio diagnóstico se efectúa para valorar varias dimensiones de la experiencia, entre ellas la evaluación, dimensión a la que se dedica este trabajo. La peculiaridad de haber integrado un proceso de autoevaluación por parte de los estudiantes para conformar su calificación del curso invita a la documentación de esta experiencia. Nuestra intención es incitar la reflexión académica acerca del proceso de evaluación ante los cambios de modalidad que se están gestando en la impartición de cursos universitarios.

  11. Paciente con síndrome de Charles Bonnet: propuesta de cuidados

    Directory of Open Access Journals (Sweden)

    M.ª Lourdes Jiménez Navascués

    Full Text Available Objetivo: El objetivo de este trabajo es mejorar la comprensión de las experiencias de los pacientes con síndrome de Charles Bonnet (SBC y proponer un plan de cuidados de enfermería. Profundizar sobre la propia experiencia del enfermo puede aportar conocimientos, que orienten a las enfermeras, en la detección de estos pacientes y a establecer un cuidado integral de la persona con SCB, aplicando la metodología de la disciplina, con el objetivo de mejorar la calidad de vida de los pacientes. Método: Revisión y análisis del caso de una mujer de 87 años de edad, con diagnóstico de degeneración macular asociada a la edad (DMAE, que causó baja visión en ambos ojos y se diagnostica con SCB en el servicio de oftalmología. Se realiza un abordaje cualitativo y se elige el relato biográfico, válido para conocer el significado de estar enfermo e incorporar la perspectiva del paciente en las intervenciones de salud. Resultados: La paciente fue diagnosticada de SCB secundario a la DMAE. Ella describe las siguientes unidades temáticas: las alucinaciones, las emociones asociadas, el diagnóstico y atención de la salud y, por último, el afrontamiento. Conclusiones: Se hace hincapié en la importancia de la ayuda profesional desde el comienzo de las alucinaciones, para evitar temores infundados y el adecuado seguimiento de su evolución.

  12. Mujeres mayas en Yucatán: experiencia participativa en una organización productiva

    Directory of Open Access Journals (Sweden)

    Amada Rubio-Herrera

    2014-01-01

    Full Text Available Presentamos resultados de investigación sobre una experiencia participativa de un grupo de mujeres maya-yucatecas: Múuch’ Meyaj Ko’olelo’ob (mmk, dando cuenta del impacto que las intervenciones de un programa universitario tienen en la vida de ellas. Utilizamos un enfoque y técnicas cualitativas. La agrupación se integró como parte del fomento a empresas sociales de mujeres rurales, emprendido por el Sistema Nacional para el Desarrollo Integral de la Familia (dif en 1997. Desde el inicio, sus integrantes se reunieron para producir y comercializar concentrado de horchata; interactuaron con agentes externos, sobresaliendo el Programa Académico de Desarrollo Sustentable en el Sur de Yucatán (padsur de la Universidad Autónoma de Yucatán (uady. Mostramos cómo este proceso se refleja en transformaciones personales identificadas por las mujeres, quienes valoran esta experiencia por posibilitar cambios en sus relaciones de género, aunque se ha incrementado su carga laboral.

  13. Noise suppressed partial volume correction for cardiac SPECT/CT

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Chung; Liu, Chi, E-mail: chi.liu@yale.edu [Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut 06520 (United States); Liu, Hui [Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut 06520 and Key Laboratory of Particle and Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084 (China); Grobshtein, Yariv [GE Healthcare, Haifa 3910101 (Israel); Stacy, Mitchel R. [Department of Internal Medicine, Yale University, New Haven, Connecticut 06520 (United States); Sinusas, Albert J. [Department of Radiology and Biomedical Imaging, Yale University, New Haven, Connecticut 06520 and Department of Internal Medicine, Yale University, New Haven, Connecticut 06520 (United States)

    2016-09-15

    Purpose: Partial volume correction (PVC) methods typically improve quantification at the expense of increased image noise and reduced reproducibility. In this study, the authors developed a novel voxel-based PVC method that incorporates anatomical knowledge to improve quantification while suppressing noise for cardiac SPECT/CT imaging. Methods: In the proposed method, the SPECT images were first reconstructed using anatomical-based maximum a posteriori (AMAP) with Bowsher’s prior to penalize noise while preserving boundaries. A sequential voxel-by-voxel PVC approach (Yang’s method) was then applied on the AMAP reconstruction using a template response. This template response was obtained by forward projecting a template derived from a contrast-enhanced CT image, and then reconstructed using AMAP to model the partial volume effects (PVEs) introduced by both the system resolution and the smoothing applied during reconstruction. To evaluate the proposed noise suppressed PVC (NS-PVC), the authors first simulated two types of cardiac SPECT studies: a {sup 99m}Tc-tetrofosmin myocardial perfusion scan and a {sup 99m}Tc-labeled red blood cell (RBC) scan on a dedicated cardiac multiple pinhole SPECT/CT at both high and low count levels. The authors then applied the proposed method on a canine equilibrium blood pool study following injection with {sup 99m}Tc-RBCs at different count levels by rebinning the list-mode data into shorter acquisitions. The proposed method was compared to MLEM reconstruction without PVC, two conventional PVC methods, including Yang’s method and multitarget correction (MTC) applied on the MLEM reconstruction, and AMAP reconstruction without PVC. Results: The results showed that the Yang’s method improved quantification, however, yielded increased noise and reduced reproducibility in the regions with higher activity. MTC corrected for PVE on high count data with amplified noise, although yielded the worst performance among all the methods

  14. Cerclaje pericostal en el tórax batiente con construcción de costillas externas artificiales

    OpenAIRE

    Bruk Bekele Jembere; Orestes N Mederos Curbelo; Jesús Valdés Jiménez; Juan Carlos Barreras Ortega; Carlos Alberto Romero Díaz; Alexis Cantero Ronquillo

    2002-01-01

    Se presenta un prototipo de fijador costal externo construido con duroaluminio maleable mediante la utilización del sistema de cerclaje AO, basado en una experiencia previa con un tórax inestable, en la cual se utilizó el sistema AO con costillas externas fabricadas de yeso y láminas de acero. La evolución de la enferma fue excelente lo que motivó a confeccionar el fijador costal reutilizable, el cual se usó después en otros 2 pacientes con resultados similares, uno de ellos con un tórax bati...

  15. Applications of cerebral SPECT

    Energy Technology Data Exchange (ETDEWEB)

    McArthur, C., E-mail: claire.mcarthur@nhs.net [Department of Neuroradiology, Institute of Neurological Sciences, Glasgow (United Kingdom); Jampana, R.; Patterson, J.; Hadley, D. [Department of Neuroradiology, Institute of Neurological Sciences, Glasgow (United Kingdom)

    2011-07-15

    Single-photon emission computed tomography (SPECT) can provide three-dimensional functional images of the brain following the injection of one of a series of radiopharmaceuticals that crosses the blood-brain barrier and distributes according to cerebral perfusion, neurotransmitter, or cell density. Applications include differentiating between the dementias, evaluating cerebrovascular disease, preoperative localization of epileptogenic foci, diagnosing movement disorders, and evaluation of intracerebral tumours, while also proving a useful research tool. Unlike positronemission tomography (PET), SPECT imaging is widely available and can be performed in any department that has access to a rotating gamma camera. The purpose of this review is to demonstrate the utility of cerebral SPECT and increase awareness of its role in the investigation of neurological and psychiatric disorders.

  16. SPECT/CT imaging in children with papillary thyroid carcinoma

    International Nuclear Information System (INIS)

    Kim, Hwa-Young; Gelfand, Michael J.; Sharp, Susan E.

    2011-01-01

    SPECT/CT improves localization of single photon-emitting radiopharmaceuticals. To determine the utility of SPECT/CT in children with papillary thyroid carcinoma. 20 SPECT/CT and planar studies were reviewed in 13 children with papillary thyroid carcinoma after total thyroidectomy. Seven studies used I-123 and 13 used I-131, after elevating TSH by T4 deprivation or intramuscular thyrotropin alfa. Eight children had one study and five children had two to four studies. Studies were performed at initial post-total thyroidectomy evaluation, follow-up and after I-131 treatment doses. SPECT/CT was performed with a diagnostic-quality CT unit in 13 studies and a localization-only CT unit in 7. Stimulated thyroglobulin was measured (except in 2 cases with anti-thyroglobulin antibodies). In 13 studies, neck activity was present but poorly localized on planar imaging; all foci of uptake were precisely localized by SPECT/CT. Two additional foci of neck uptake were found on SPECT/CT. SPECT/CT differentiated high neck uptake from facial activity. In six studies (four children), neck uptake was identified as benign by SPECT/CT (three thyroglossal duct remnants, one skin contamination, two by precise anatomical CT localization). In two children, SPECT/CT supported a decision not to treat with I-131. When SPECT/CT was unable to identify focal uptake as benign, stimulated thyroglobulin measurements were valuable. In three of 13 studies with neck uptake, SPECT/CT provided no useful additional information. SPECT/CT precisely localizes neck iodine uptake. In small numbers of patients, treatment is affected. SPECT/CT should be used when available in thyroid carcinoma patients. (orig.)

  17. 65. Embolización de fuga periprotésica mitral por abordaje transapical: A propósito de un caso. Experiencia inicial en nuestro medio

    Directory of Open Access Journals (Sweden)

    E. Martín

    2012-04-01

    Conclusiones: a pesar de tratarse de una experiencia inicial en nuestro medio, la embolización de fugas perivalvulares constituye una alternativa multidisciplinaria, segura y que permite el tratamiento de pacientes con alto riesgo/fragilidad para el abordaje quirúrgico convencional.

  18. Radiopharmaceuticals for SPECT cancer detection

    Energy Technology Data Exchange (ETDEWEB)

    Chernov, V. I., E-mail: chernov@oncology.tomsk.ru; Medvedeva, A. A., E-mail: tickayaAA@oncology.tomsk.ru; Zelchan, R. V., E-mail: r.zelchan@yandex.ru; Sinilkin, I. G., E-mail: sinilkinig@oncology.tomsk.ru [Tomsk Cancer Research Institute, Kooperativny Street 5, Tomsk, 634050 (Russian Federation); Tomsk Polytechnic University, Lenin Avenue 30, Tomsk, 634050 (Russian Federation); Stasyuk, E. S.; Larionova, L. A. [Tomsk Polytechnic University, Lenin Avenue 30, Tomsk, 634050 (Russian Federation); Slonimskaya, E. M.; Choynzonov, E. L. [Tomsk Cancer Research Institute, Kooperativny Street 5, Tomsk, 634050 (Russian Federation)

    2016-08-02

    The purpose of the study was to assess the efficacy of single photon emission computed tomography (SPECT) with {sup 199}Tl and {sup 99}mTc-MIBI in the detection of breast, laryngeal and hypopharyngeal cancers. A total of 220 patients were included into the study: 120 patients with breast lesions (100 patients with breast cancer and 20 patients with benign breast tumors) and 100 patients with laryngeal/hypopharyngeal diseases (80 patients with laryngeal/hypopharyngeal cancer and 20 patients with benign laryngeal/hypopharyngeal lesions). No abnormal {sup 199}Tl uptake was seen in all patients with benign breast and laryngeal lesions, indicating a 100% specificity of {sup 199}Tl SPECT. In the breast cancer patients, the increased {sup 199}Tl uptake in the breast was visualized in 94.8% patients, {sup 99m}Tc-MIBI—in 93.4% patients. The increased {sup 199}Tl uptake in axillary lymph nodes was detected in 60% patients, and {sup 99m}Tc-MIBI—in 93.1% patients. In patients with laryngeal/hypopharyngeal cancer, the sensitivity of SPECT with {sup 199}Tl and {sup 99m}Tc-MIBI was 95%. The {sup 199}Tl SPECT sensitivity in identification of regional lymph node metastases in the patients with laryngeal/hypopharyngeal cancer was 75% and the {sup 99m}Tc-MIBI SPECT sensitivity was 17%. The data obtained showed that SPECT with {sup 199}Tl and {sup 99m}Tc-MIBI can be used as one of the additional imaging methods in detection of tumors.

  19. Experiencias dendroclimáticas con árboles de ecosistemas contrastantes de Colombia

    Directory of Open Access Journals (Sweden)

    Herrera David Andrés

    2012-12-01

    Full Text Available Este trabajo presenta los resultados de diferentes investigaciones dendroclimaticas realizadas en tres ecosistemas contrastantes de Colombia. Se emplearon técnicas dendrocronologicas y densitogramas computarizados para obtener las cronologías de crecimiento y densidad, respectivamente. Se encontraron asociaciones significativas entre las cronologías, las variables climáticas locales y el ENSO, por ejemplo: la densidad de los anillos de crecimiento de Rhizophora mangle con la precipitación; el ancho de los anillos de crecimiento de Parkinsonia praecox y Capparis odoratissima con la precipitación, la temperatura del aire y la temperatura superficial del mar, y el ancho de los anillos de crecimiento de Prioria copaifera con las alturas limnimetricas del rio Atrato. Dichos resultados demuestran la aplicabilidad y el potencial de la dendroclimatologia en regiones tropicales.

  20. Experiencias dendroclimáticas con árboles de ecosistemas contrastantes de Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Ignacio del Valle

    2012-07-01

    Full Text Available Este trabajo presenta los resultados de diferentes investigaciones dendroclimaticas realizadas en tres ecosistemas contrastantes de Colombia. Se emplearon técnicas dendrocronologicas y densitogramas computarizados para obtener las cronologías de crecimiento y densidad, respectivamente. Se encontraron asociaciones significativas entre las cronologías, las variables climáticas locales y el ENSO, por ejemplo: la densidad de los anillos de crecimiento de Rhizophora mangle con la precipitación; el ancho de los anillos de crecimiento de Parkinsonia praecox y Capparis odoratissima con la precipitación, la temperatura del aire y la temperatura superficial del mar, y el ancho de los anillos de crecimiento de Prioria copaifera con las alturas limnimetricas del rio Atrato. Dichos resultados demuestran la aplicabilidad y el potencial de la dendroclimatologia en regiones tropicales.

  1. Cambiemos la percepción social hacia las personas con discapacidad desde el Servicio Comunitario

    Directory of Open Access Journals (Sweden)

    Zuleima Corredor Ponce

    2017-12-01

    Full Text Available Este artículo da cuenta de una experiencia desarrollada en la Universidad Nacional Abierta (UNA, Centro Local Zulia, relativa al diseño e implementación de un proyecto socioeducativo, cuyo objetivo fue promover un cambio en la percepción social hacia las personas con discapacidad, desde la actividad de Servicio Comunitario, para configurar una cultura inclusiva. El proyecto fue propuesto desde la UNA y se implementó una primera experiencia mediante una alianza estratégica con estudiantes de Servicio Comunitario de la Universidad Rafael Belloso Chacín (URBE. Se concluye que las alianzas entre universidades son una valiosa oportunidad para contribuir a la resolución de problemáticas sociales complejas, mediante proyectos de alto impacto; se observó un desplazamiento conductual en relación al tema en los estudiantes prestadores del servicio y se logró formar y sensibilizar a la comunidad. Se espera identificar nuevos nodos y consolidar una red interinstitucional en la que las personas con discapacidad sean actores fundamentales.

  2. Aportes para una vida saludable. Proceso socioeducativo con estudiantes de primer ingreso, Universidad Nacional

    OpenAIRE

    Gonzalez-Soto, L.; Orozco-Morales, A.R.

    2017-01-01

    Propósito: Exponer la experiencia de medir en algún grado el impacto social de un proceso socioeducativo anual, desarrollado con 800 estudiantes de primer ingreso provenientes de diversos lugares del país, con limitadas condiciones socioeconómica y quienes son beneficiarios de beca para sus estudios. El proceso consistió en establecer 4 o 5 eventos anuales y trabajar con metodologías lúdicas temas alusivos a estilos de vida saludables. Material y método: Se aplicó la técnica de grupo focal al...

  3. Modelo de gestión cultural para el arte itinerante con ciencia y tecnología

    OpenAIRE

    Corredor Rodríguez, Laura Marcela; Dunga, Catherine; Jaramillo Strouss, Juliana; Rave Contreras, Fabio

    2015-01-01

    Diseñar un modelo de gestión cultural que busca llevar el arte, la ciencia y la tecnología a distintas regiones y ciudades del país, iniciando en la ciudad de Tunja, por medio de una exposición itinerante que vincule estos tres campos de una manera transversal con el fin de acercar a los distintos públicos a experiencias vivenciales de aprendizajes, interacción y exploración. Estas experiencias tendrán lugar por medio de contenedores.

  4. Una vida con una válvula: vivencias de una joven operada de corazón

    OpenAIRE

    María Correa Rodríguez; José Antonio Gutiérrez Romero; Juan Manuel Martínez Guerrero

    2013-01-01

    La informante del relato es una joven que tuvo que ser sometida a una intervención quirúrgica a corazón abierto. Este relato biográfico presenta sus vivencias, sentimientos y experiencias a lo largo del proceso, abarcando desde sus estancias hospitalarias, manejo de la enfermedad y situación actual. El objetivo del relato es describir el significado las experiencias relacionadas con la enfermedad que ha desarrollado la joven en las distintas etapas de su vida. Es una historia marcada por el e...

  5. SPECT of the brain: Present and future

    International Nuclear Information System (INIS)

    Fazio, F.; Lenzi, G.L.

    1986-01-01

    In both PET and SPECT, most of the studies and the models have been addressed to two organs: brain and heart. So far, brain has certainly been investigated more. The several comparisons between planar scintigraphy and SPECT, between X-ray TCT and SPECT, and also between PET and SPECT, have tended to consider SPECT a cheap but scarcely useful tool for a nuclear medicine section. Again the authors feel that this is due to the fact that SPECT is really a ''physiological tomography'', with little known about its physiology or how it is measured. Thus the present state of the art of SPECT of the brain is characterized by a collection of data and reports on brain imaging and by a slowly growing basic understanding of the utilized modes. The introduction of a new brain-imaging radiopharmaceutical is immediately signaled by its ''first clinical application'' without parallel studies on the kinetics, the metabolic degradation, and the real suitability of the molecule as a tracer for measurement of regional CBF. Only a few attempts seek to narrow this discussion between clinic and biology, and the authors like to emphasize the need for nuclear medicine people to dedicate more time and effort

  6. 123I-iomazenil brain receptor SPECT in focal epilepsy. In comparison with 99mTc-HMPAO brain SPECT, MRI and Video/EEG monitoring

    International Nuclear Information System (INIS)

    Xu Hao; Wang Tongge; Huang Li; Michael Cordes

    1998-01-01

    Purpose: To evaluate the clinical value of 123 I-Iomazenil brain receptor SPECT in diagnosis of focal epilepsy in comparison with 99m Tc-HMPAO brain SPECT, MRI and Video/EEG monitoring. Methods 123 I-Iomazenil brain receptor SPECT was performed on 40 patients with focal epilepsy. The results were compared with those obtained by 99m Tc-HMPAO brain SPECT, MRI and Video/EEG monitoring. Results: In 40 patients, the sensitivity of Video/EEG monitoring for localization of epileptogenic area was 95% (38/40). The sensitivity of 123 I-iomazenil brain receptor SPECT, 99m Tc-HMPAO brain SPECT and MRI for localization of epileptogenic area compared with Video/EEG monitoring ('gold standard') was 65.8%(25/38), 55.3%(21/38) and 47.4%(18/38), respectively. The localization of epileptogenic area with 123 I-Iomazenil brain receptor SPECT was in concordance with Video/EEG monitoring in 20 patients, 99m Tc-HMPAO brain SPECT in 15 patients and MRI in 16 patients, respectively. The sensitivity of 123 I-Iomazenil brain receptor SPECT combined with MRI for localization of epileptogenic area was 84.2%(32/38). Conclusions: 123 I-Iomazenil brain receptor SPECT is a useful method in detecting and localizing epileptogenic area. The combination of 123 I-Iomazenil brain receptor SPECT and MRI has a high sensitivity for detecting epileptogenic area

  7. La narración oral como herramienta en la construcción de la memoria colectiva de la violencia. Experiencia con mujeres víctimas de desplazamiento forzado en Colombia

    Directory of Open Access Journals (Sweden)

    Laura Juliana Soto Moreno

    2014-01-01

    Full Text Available Este artículo tiene como insumo las entrevistas realizadas a ocho mujeres habitantes de Soacha y víctimas del desplazamiento forzado. Estas son resultado de la investigación y el trabajo de campo ejecutado en el municipio de Soacha, durante los años 2011 y 2012. Se trata de un estudio de corte cualitativo. Para la recolección de información se utilizó la técnica de historia de vida o storytelling, para encontrar cómo se configuraba la construcción de memoria colectiva en el proceso de interacción de las mujeres con su pasado y su actual entorno. En el análisis se quiso enfatizar en los conceptos que integran el cuerpo de estudio de la memoria individual y la memoria colectiva. El proceso de investigación tuvo como objetivo principal reconstruir las experiencias vitales de personas en situación de desplazamiento antes, durante y después de su vivencia del conflicto, destacando las permanencias y cambios que se presentaron en los aspectos culturales con la llegada al nuevo contexto.

  8. Clinical evaluation of stress thallium spect in ischemic heart disease

    International Nuclear Information System (INIS)

    Sui, Osamu; Kimura, Nazuna; Soeki; Takeshi; Takeichi, Naoki; Shinohara, Hisanori; Tamura, Yoshiyuki; Fukuda, Nobuo

    1997-01-01

    Thallium SPECT was performed in patients with significant coronary artery stenosis, 67 cases were after maximal exercise and 74 cases were during coronary vasodilation induced by ATP (adenosine triphosphate) infusion. In patients suspected of angina pectoris, the sensitivity, specificity and predictive accuracy for detection of coronary artery disease (CAD) were 88%, 78% and 82% for exercise SPECT, and 100%, 72% and 84% for ATP SPECT studies, respectively. In patients with old myocardial infarction, these were 73%, 100% and 88% for exercise SPECT and 71%, 100% and 81% for ATP SPECT. These were 75%, 49% and 60% for treadmill exercise test in the patient group including both angina and myocardial infarction. For detection of diseased vessels, the diagnostic accuracy for left anterior descending artery and right coronary artery lesions was almost equal for ATP and exercise SPECT study, but ATP SPECT study was more sensitive than exercise SPECT study in detection of left circumflex artery lesions. ATP as well as exercise SPECT studies occasionally gave false positive results in patients with single-vessel disease. ATP as well as exercise SPECT studies underestimated the severity of multi-vessel disease. In general, the results of ATP SPECT imaging were highly concordant with the results of exercise SPECT imaging. ATP stress thallium SPECT imaging provided a safe and highly accurate diagnostic tool for detection of CAD. (author)

  9. Gated 99mTc-MIBI single-photon emission computed tomography for the evaluation of left ventricular ejection fraction. Comparison with three-dimensional echocardiography

    International Nuclear Information System (INIS)

    Lipiec, P.; Wejner-Mik, P.; Krzeminska-Pakula, M.; Kapusta, A.; Kasprzak, J.D.; Kusmierek, J.; Plachcinska, A.; Szuminski, R.

    2008-01-01

    Parameters of left ventricular systolic function directly influence the management of patients with suspected coronary artery disease (CAD). Quantitative gated single-photon emission computed tomography (QGS; Cedars-Sinai Medical Center, Los Angeles, CA, USA) allows the computation of left ventricular ejection fraction (LVEF) from myocardial perfusion imaging studies which are frequently performed on patients with suspected CAD. Three-dimensional (3D) echocardiography is considered to be the echocardiographic ''gold standard'' for the quantification of LVEF. We sought to compare QGS with 3D echocardiography in the evaluation of EF in patients with suspected CAD. Ninety-one consecutive patients with suspected CAD, scheduled for coronary angiography, underwent rest electrocardiographic-gated technetium-99m methoxyisobutylisonitrile SPECT (G-SPECT) with measurement of LVEF by QGS and transthoracic 3D echocardiography with off-line measurement of LVEF (Tomtec 4D LV Analysis 1.1). The diagnosis of CAD was based on coronary angiography, performed on every patient. Nine patients were excluded from the analysis owing to unsuitability for 3D echocardiography (8 patients) or G-SPECT (1 patient). In the remaining group of 82 patients, 71 (87%) had significant CAD, 34 (42%) had a history of myocardial infarction, and 50 (61%) had perfusion defects at rest G-SPECT images. The mean LVEF measured by QGS and 3D echocardiography was 53±13% and 53±10%, respectively. The mean difference in LVEF between 3D echocardiography and QGS was 0.1±6.0% (P=0.87), and the correlation between the values obtained by both methods was high (r=0.88, P< 0.001). The largest discrepancies were observed in patients with small ventricular volumes. In patients undergoing diagnostic work-up for CAD, the measurement of LVEF by QGS algorithm provides high correlation and satisfactory agreement with the results of reference ultrasound method- 3D echocardiography. (author)

  10. Mnemonic activation by SPECT

    International Nuclear Information System (INIS)

    Migneco, O.; Darcourt, J.; Benoit, M; Malandain, G.; Thirion, J.P.; Robert, Ph.; Vidal, R.; Desvignes, Ph.; Benoliel, J.; Ayache, N.; Bussiere, F.

    1997-01-01

    Data of literature show that SPECT is able to detect cerebral activations induced by sensory-motor stimuli. The facts are not clearly established in what concerns the cognitive activations the amplitude of which is lower. We have studied an activation paradigm such as the Grober and Bruschke test which implies the long term explicit memory. It comprises a visual presentation of words followed by their indexed recall. By using a two-day protocol, 2 SPECTs were achieved in 4 healthy right-handed voluntaries as follows: one of activation (A) and one of control (B). The fifth subject benefited by a SPECT B and of an MRI. The injection for the examination A has been done during the indexed recall stage and for the examination B at the moment when the patient repeated several times the same 3 words. The SPECT data were collected 1 hour after the injection of 370 MBq of ECD making use of a 3-head camera equipped with UHR fan collimators and ending by a LMH on the reconstructed images of 8 mm. The MRI has been achieved by means of a Signa 1.5 Tesla magnet. The SPECT A and B of the subjects 1 to 4 were matched elastically to that of the subject 5 and that of the subject 5 was rigidly matched on its MRI. In this way the individual activation cards of the 4 subjects could be averaged and superimposed on the MRI of the 5. subject. One observes an internal temporal activation (maximal activation of left tonsil, +25% and right uncus, +23%) and a right cingulum activation (maximal activation, +25%), in agreement with the neuro-physiological data. The elastic matching makes possible the inter-subject averaging, what increases the signal-to-noise ratio of activation. The inter-modality rigid matching facilitates the anatomical localisation of the activation site. With these adapted tools, the cognitive activation is thus possible by SPECT and opens perspectives for early diagnosis of neurological troubles, namely of Alzheimer's disease

  11. Experiencias exitosas de liderazgo en enfermería

    Directory of Open Access Journals (Sweden)

    Mery Luz Valderrama Sanabria

    2014-11-01

    Full Text Available Introducción: El objetivo de la investigación fue describir la experiencia de profesionales de enfermería en cargos administrativos en salud para fomentar el liderazgo en el futuro profesional de enfermería. Materiales y Métodos: Investigación cualitativa tipo descriptivo, con diseño narrativo de tópicos puesto que se enfoca en una temática que hace referencia al liderazgo en enfermería. Resultados: Se obtuvieron tres categorías: Experiencias exitosas, de la cual surgieron dos subcategorías: óptimo uso de los recursos y cuidado desde cargos directivos. Las otras categorías se denominaron; liderazgo en enfermería y   profesional del futuro. Discusión: Los resultados fueron analizados a la luz de la literatura encontrando semejanzas en cuanto a que el mercado laboral solicita del enfermero la aplicación del liderazgo y se debe redimensionar la formación del futuro profesional y nuevos escenarios de práctica para que responda a las necesidades de un país. Conclusiones: Las dificultades se presentan para ejercer liderazgo al inicio de la vida laboral son el temor, desconocimiento de los derechos como empleado y no saber cuánto vale el trabajo de enfermería. Posteriormente se van presentando por malos entendidos, relaciones interpersonales poco adecuadas, ausencia de colegaje y falta de posicionamiento y reconocimiento de la profesión. Ser líder es un proceso casi inherente a enfermería ya sea desde el ámbito clínico, comunitario o a través del ejercicio de cargos administrativos y se debe fomentar y potenciar en el estudiante.Palabras clave: Liderazgo, Enfermeros, Educación Continua, Satisfacción en el Trabajo. (Fuente: DeCS BIREME.Cómo citar este artículo: Valderrama ML. Experiencias exitosas de liderazgo en enfermería. Rev Cuid. 2014; 5(2: 765-73. http://dx.doi.org/10.15649/cuidarte.v5i2.89

  12. SPECT quantification of regional radionuclide distributions

    International Nuclear Information System (INIS)

    Jaszczak, R.J.; Greer, K.L.; Coleman, R.E.

    1986-01-01

    SPECT quantification of regional radionuclide activities within the human body is affected by several physical and instrumental factors including attenuation of photons within the patient, Compton scattered events, the system's finite spatial resolution and object size, finite number of detected events, partial volume effects, the radiopharmaceutical biokinetics, and patient and/or organ motion. Furthermore, other instrumentation factors such as calibration of the center-of-rotation, sampling, and detector nonuniformities will affect the SPECT measurement process. These factors are described, together with examples of compensation methods that are currently available for improving SPECT quantification. SPECT offers the potential to improve in vivo estimates of absorbed dose, provided the acquisition, reconstruction, and compensation procedures are adequately implemented and utilized. 53 references, 2 figures

  13. REVISIÓN DE LAS EXPERIENCIAS EN EL TRATAMIENTO DE AGUAS RESIDUALES DOMÉSTICAS MEDIANTE REACTORES UASB EN COCHABAMBA-BOLIVIA COMPARADAS CON LAS DE LATINOAMÉRICA, INDIA Y EUROPA

    Directory of Open Access Journals (Sweden)

    Vanessa Gandarillas R.

    2017-06-01

    Full Text Available El proceso de tratamiento anaeróbico es cada vez más reconocido como opción viable para la protección del medio ambiente y la conservación de los recursos y representa, combinado con otros métodos adecuados, un sistema de tratamiento de aguas residuales sostenible y apropiado para los países en vías de desarrollo. El tratamiento anaeróbico de aguas residuales se está utilizando con éxito en los países tropicales desde la década de los 80, y con resultados alentadores en las regiones subtropicales y templadas. En este estudio se revisan las principales características del tratamiento de aguas residuales domésticas, con énfasis en el Reactor Anaeróbico de Mantos de Lodos de Flujo Ascendente (RALF o Upflow Anaerobic Sludge Blanket (UASB de su sigla en inglés. Se revisaron las aplicaciones del proceso UASB en Europa, Asia y las Américas. En Latino América y en particular en Bolivia el uso de esta tecnología ha incrementado considerablemente debido a la pequeña demanda de terreno requerida para su implementación y a sus atractivos costos de inversión y operación. La revisión mostró, en base a la experiencia de operación de distintas plantas de tratamiento ubicadas en los valles de Cochabamba, que los reactores anaerobios de mantos de lodos de flujo ascendente apropiadamente diseñados, son adecuados para el tratamiento de aguas residuales domésticas en las regiones de los valles y llanos de Bolivia debido a que presentan condiciones ambientales que hacen que el uso de esta biotecnología anaerobia sea favorable bajo la perspectiva del desarrollo sostenible.

  14. Radionuclide cisternography: SPECT and 3D-rendering. Radionuklidzisternographie: SPECT- und 3D-Technik

    Energy Technology Data Exchange (ETDEWEB)

    Henkes, H; Huber, G; Piepgras, U [Universitaet des Saarlandes, Homburg/Saar (Germany, F.R.). Abt. fuer Neuroradiologie; Hierholzer, J [Freie Univ. Berlin (Germany, F.R.). Strahlenklinik und Poliklinik; Cordes, M [British Columbia Univ., Vancouver, BC (Canada). Belzberg Lab. of Neuroscience

    1991-10-01

    Radionuclide cisternography is indicated in the clinical work-up for hydrocephalus, when searching for CSF leaks, and when testing whether or not intracranial cystic lesions are communicating with the adjacent subarachnoid space. This paper demonstrates the feasibility and diagnostic value of SPECT and subsequent 3D surface rendering in addition to conventional rectilinear CSF imaging in eight patients. Planar images allowed the evaluation of CSF circulation and the detection of CSF fistula. They were advantageous in examinations 48 h after application of {sup 111}In-DTPA. SPECT scans, generated 4-24 h after tracer application, were superior in the delineation of basal cisterns, especially in early scans; this was helpful in patients with pooling due to CSF fistula and in cystic lesions near the skull base. A major drawback was the limited image quality of delayed scans, when the SPECT data were degraded by a low count rate. 3D surface rendering was easily feasible from SPECT data and yielded high quality images. The presentation of the spatial distribution of nuclide-contaminated CSF proved especially helpful in the area of the basal cisterns. (orig.).

  15. Design of common software for quality control of SPECT

    International Nuclear Information System (INIS)

    Li Xiaohua; Gao Ruzhen; Chen Shengzu

    1993-01-01

    The goal of this study is to design a common testing system for SPECT quality control according to NEMA standard. Using the system, the performances of different types of SPECT can be tested, so that the acceptance testing, performance comparing and routine quality control for SPECT can be normalized. The system was based on IBM PC series of microcomputer. Testing data are acquired from various types of SPECT, then transferred into IBM PC through interface and tested with an unique testing program. Two parts were included: interface and SPECT testing program. It emphatically studied the managing program of RS232 interface, designing skills and the mathematic patterns of SPECT testing program. The system which was composed of 11 subroutines can be used to measure the performances for both gamma camera and SPECT. The system was tested on OMEGA 500/MCS 560 SPECT and the results showed that it is effective, accurate and easy to use

  16. Scatter and cross-talk correction for one-day acquisition of 123I-BMIPP and 99mtc-tetrofosmin myocardial SPECT.

    Science.gov (United States)

    Kaneta, Tomohiro; Kurihara, Hideyuki; Hakamatsuka, Takashi; Ito, Hiroshi; Maruoka, Shin; Fukuda, Hiroshi; Takahashi, Shoki; Yamada, Shogo

    2004-12-01

    123I-15-(p-iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) and 99mTc-tetrofosmin (TET) are widely used for evaluation of myocardial fatty acid metabolism and perfusion, respectively. ECG-gated TET SPECT is also used for evaluation of myocardial wall motion. These tests are often performed on the same day to minimize both the time required and inconvenience to patients and medical staff. However, as 123I and 99mTc have similar emission energies (159 keV and 140 keV, respectively), it is necessary to consider not only scattered photons, but also primary photons of each radionuclide detected in the wrong window (cross-talk). In this study, we developed and evaluated the effectiveness of a new scatter and cross-talk correction imaging protocol. Fourteen patients with ischemic heart disease or heart failure (8 men and 6 women with a mean age of 69.4 yr, ranging from 45 to 94 yr) were enrolled in this study. In the routine one-day acquisition protocol, BMIPP SPECT was performed in the morning, with TET SPECT performed 4 h later. An additional SPECT was performed just before injection of TET with the energy window for 99mTc. These data correspond to the scatter and cross-talk factor of the next TET SPECT. The correction was performed by subtraction of the scatter and cross-talk factor from TET SPECT. Data are presented as means +/- S.E. Statistical analyses were performed using Wilcoxon's matched-pairs signed-ranks test, and p corrected total count was 26.0 +/- 5.3%. EDV and ESV after correction were significantly greater than those before correction (p = 0.019 and 0.016, respectively). After correction, EF was smaller than that before correction, but the difference was not significant. Perfusion scores (17 segments per heart) were significantly lower after as compared with those before correction (p correction revealed significant differences in EDV, ESV, and perfusion scores. These observations indicate that scatter and cross-talk correction is required for one

  17. SPECT and PET imaging in epilepsy

    International Nuclear Information System (INIS)

    Semah, F.

    2007-01-01

    Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging are very useful for the management of patients with medically refractory partial epilepsy. Presurgical evaluation of patients with medically refractory partial epilepsy often included PET imaging using FDG. The use of SPECT in these patients adds some more information and gives the clinicians the possibility of having ictal imaging. Furthermore, PET and SPECT imaging are performed to better understand the pathophysiology of epilepsy. (authors)

  18. Juegos digitales desde el punto de vista de los profesores. Una experiencia didáctica en aulas primaria catalanas

    Directory of Open Access Journals (Sweden)

    José Luis EGUIA-GÓMEZ

    2015-07-01

    Full Text Available Este artículo presenta una experiencia didáctica centrada en la aplicación de un juego digital en las aulas catalanas de quinto y sexto grado de educación primaria. En él se explica y analizan los efectos de su aplicación en la práctica docente, tomando el punto de vista de los docentes que participaron de la experiencia. El documento se basa en el juego digital llamado Miquel Crusafont, un juego que cuenta con el apoyo de la Generalitat de Catalunya. El estudio obtiene las opiniones de un grupo seleccionado de once profesores –con edades entre 24 y 52– en relación a dicha innovación metodológica. Se llevaron acabo entrevistas con el fin de obtener el punto de vista del profesorado. Los resultados muestran que los educadores aprecian la potencialidad del juego digital para desarrollar diversas habilidades a través de áreas como las matemáticas y consideran la forma en como pueden alentar a los estudiantes a realizar algunas actividades de aprendizaje colaborativo. Señalaron, además, algunas dificultades para utilizar un juego digital de estas características en las aulas: falta un tiempo destinado específicamente a ello en el plan de estudios, algunos juegos en el mercado no son apropiados para la enseñanza o no cuentan con un manual de uso que muestre la potencialidad del juego.

  19. Brain spect imaging

    International Nuclear Information System (INIS)

    Lee, R.G.L.; Hill, T.C.; Holman, B.L.

    1989-01-01

    This paper discusses how the rapid development of single-photon radiopharmaceuticals has given new life to tomographic brain imaging in nuclear medicine. Further developments in radiopharmaceuticals and refinements in neuro-SPECT (single-photon emission computed tomography) instrumentation should help to reinstate brain scintigraphy as an important part of neurologic diagnosis. SPECT of the brain evolved from experimentation using prototype instrumentation during the early 1960s. Although tomographic studies provided superior diagnostic accuracy when compared to planar techniques, the arrival of X-ray CT of the head resulted in the rapid demise of technetium brain imaging

  20. INTUICIÓN, LA EXPERIENCIA Y EL TIEMPO EN EL PENSAMIENTO DE BERGSON

    OpenAIRE

    Ruiz Stull,Miguel

    2009-01-01

    Esta indagación sobre la relación entre experiencia y tiempo en la obra de Henri Bergson tiene como propósito articular ambas nociones a partir de un análisis de la operación de la intuición en el contexto del pensamiento bergsoniano. De este modo, será posible considerar que el método de la intuición cobra un rol esencial en la emergencia de conceptos como duración, memoria y elan vital, los cuales colocan en relieve el singular empirismo con que puede ser ilustrado el discurso filosófico de...