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  1. Intervenciones Farmaceuticas en pacientes con Diabetes Mellitus Tipo 2

    Directory of Open Access Journals (Sweden)

    Gladys Mabel Maidana

    Full Text Available Resumen Introducción: La Atención Farmacêutica es la provision responsable de la farmacoterapia con el propósito de alcanzar resultados concretos que mejoren la calidad de vida de los pacientes. Objetivo: Evaluar el impacto de las intervenciones farmacéuticas en pacientes con Diabetes Mellitus Tipo 2. Metodologia: Ensayo Clínico Aleatorizado, con medición de variables antes y después. No probabilísti-co. De conveniencia. Participaron 32 pacientes del grupo intervenido y 32 en grupo control. Se realizaron entrevistas mensuales en un periodo de intervención farmacéutica de 6 meses (desde octubre 2011 hasta junio 2012. Se registraron solo 3 abandonos. Resultados: La edad de los pacientes fue 55,6±10,6 anos. Los pacientes del grupo intervenido mejoraron la glicemia en 34%, donde 24 pacientes tenian el valor (< 130 mg/dL; la hemoglobina glicosilada mejoró 1,9%, donde 15 pacientes lograron los parámetros deseados (< 6,5%. La calidad de vida del grupo inter-venido aumentó de (56,3 a 71,3 % y fue medido con el cuestionario SF-36. En el grupo intervenido se encontraron 80 problemas relacionados con medicamentos, en 27 pacientes, se resolvieron 59; al final del estudio 12 pacientes resolvieron todos los problemas relacionados con medicamentos; se realizaron 254 intervenciones farmacêuticas, el nivel de conocimiento de los pacientes sobre la enfermedad mejoró en 41%, el conocimiento sobre sus medicamentos mejoró en 53%. Conclusión: Las intervenciones farmacêuticas mejoraron los parámetros clínicos de glicemia, hemoglobina glicosilada, optimizaron el uso de medicamentos, disminuyeron los problemas relacionados con medicamentos, mejoraron la calidad de vida de los pacientes.

  2. Diabetes mellitus en el paciente con enfermedad renal avanzada

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    R. Verner Codoceo, Dr.

    2010-07-01

    Full Text Available La diabetes mellitus 2 (DM 2 y la enfermedad renal crónica (ERC son considerados problemas de salud pública a nivel mundial. Los pronósticos de ambas enfermedades están estrechamente relacionados, por lo que las acciones terapéuticas son complementarias. Un buen control glicémico revierte las alteraciones renales en sus etapas iniciales disminuyendo el deterioro microangiopático ya su vez el intento de obtener un control óptimo de glicemias requiere conocer y tratar las alteraciones provocadas por el ambiente urémico. Es muy importante considerar la existencia de cambios en la interpretación de los análisis de laboratorio, cambios en la farmacocinética y farmacodinamia de los medicamentos hipoglicemiantes e insulinas y finalmente la existencia de dificultades para realizar ejercicios y administrar una alimentación adecuada. Los esquemas de hipoglicemiantes utilizados, tanto medicamentos orales como insulinas, deben ser cuidadosamente personalizados. Se debe evitar la indicación de medicamentos de excreción renal exclusiva por el riesgo de hipoglicemias. Tanto las insulinas análogas como convencionales pueden ser administradas, con precaución en su dosificación y reconociendo la necesidad de un estricto automonitoreo de glicemia digital.

  3. Diabetes mellitus en el paciente con enfermedad renal avanzada

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    R. Verner Codoceo, Dr.

    2010-01-01

    La diabetes mellitus 2 (DM 2) y la enfermedad renal crónica (ERC) son considerados problemas de salud pública a nivel mundial. Los pronósticos de ambas enfermedades están estrechamente relacionados, por lo que las acciones terapéuticas son complementarias. Un buen control glicémico revierte las alteraciones renales en sus etapas iniciales disminuyendo el deterioro microangiopático ya su vez el intento de obtener un control óptimo de glicemias requiere conocer y tratar las alteraciones provoca...

  4. Mucormicosis rinocerebral en paciente con cefalea y diabetes mellitus Rhinocerebral mucormycosis in diabetic patient with headache

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    Juan Camilo Botero

    2008-03-01

    Full Text Available Se reporta el caso de un paciente masculino de 52 años, con antecedentes personales de diabetes mellitus tipo 2 en tratamiento con metformín quien consultó por cefalea intensa y congestión nasal. Se diagnosticó una pansinusitis que no respondió al manejo médico. Fue evaluado por medicina interna y otorrinolaringología y se encontraron costras secas, negras, en los cornetes y meatos mediante la fibronasolaringoscopia. Se practicó una resonancia magnética en la que se reportó una lesión en la región temporal izquierda asociada a edema vasogénico. Se programó para drenaje del absceso el cual se realizó sin complicaciones; en el estudio de histopatología se informó la presencia de hifas aseptadas que correspondían a Rhizopus sp. Se inició su manejo con anfotericina B para la mucormicosis rinocerebral con respuesta adecuada y se dio de alta por mejoría de su enfermedad.We report the case of a 52 years old male patient with type 2 diabetes mellitus under metformin therapy that presented with acute headache and nasal congestion. Pansinusitis was diagnosed which did not respond to medical treatment. He was evaluated by the internal medicine and otorrinolaringology departments. In the fibronasolaringoscopy exam black necrotic scars were found in turbinates and meatus. A magnetic resonance was ordered which evidenced a lesion in the left temporal region associated to vasogenic edema. The patient was programmed for abscess drainage without any complications; the histopathological report informed the presence of non septated hyphae compatible with Rhizopus sp. The patient began to receive amphotericyn B for a rhinocerebral mucormycosis with optimal response and was discharged with improvement of his clinical picture.

  5. Consumo de frutos secos y aceites vegetales en personas con diabetes mellitus tipo 1

    OpenAIRE

    Ferrer-García, Juan Carlos; Granell Vidal, Lina; Muñoz Izquierdo, Amparo; Sánchez Juan, Carlos

    2015-01-01

    Introducción: estudios recientes han demostrado los beneficios cardiovasculares de la dieta mediterránea enriquecida con aceite de oliva y frutos secos. Las personas con diabetes, que tienen un mayor riesgo de complicaciones cardiovasculares, podrían beneficiarse en gran medida de seguir ese tipo de patrón alimentario. Objetivos: análisis de la ingesta de grasas vegetales procedentes de frutos secos y aceites vegetales en pacientes con diabetes mellitus tipo 1 (DM1). Métodos: estudio transver...

  6. Estudio del fenotipo de haptoglobinas en pacientes con diabetes mellitus tipo 1, en Lima, Perú

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    Arias, Clever; Inga, Miriam; Oré, Raquel; Zapata, Luis; Aquije, Carmen

    2013-01-01

    Objetivos: Determinar el fenotipo de haptoglobina -1/1, 1/2 y 2/2- predominante en una muestra de 36 pacientes con diabetes mellitus tipo I (DM tipo I). Diseño: Observacional con sistema de medición, descriptivo. Institución: Centro de Investigación de Bioquímica y Nutrición, Facultad de Medicina, UNMSM. Participantes: Pacientes con diagnóstico de diabetes mellitus tipo I Intervenciones: En 36 pacientes con diagnóstico de diabetes mellitus tipo I, se realizó medidas antropométricas, evaluacio...

  7. Condiciones biopsicosociales de adultos mayores mexicanos con diabetes mellitus.

    Science.gov (United States)

    Guzmán-Olea, Eduardo; López-Romero, David; Torres-Poveda, Kirvis; Madrid-Marina, Vicente; Luna-Muñoz, José; Pimentel-Pérez, Bertha Maribel; Agis-Juárez, Raúl Azael

    2017-01-01

    Diabetes mellitus (DM) is a global health problem, which significantly affects older adults. . The prevalence and biopsychosocial conditions of DM in older adults in the State of Hidalgo, Mexico, are analyzed using the Health and Aging Survey 2014 (SABE-Hidalgo, Mexico). DM in older adults presents a prevalence of 28.22% in the State, predominating in women and becoming more common with increasing age. The highest frequency occurs in residents of urban areas (57.2%), those with less schooling (79.6%), and those who live with relatives (77%). In addition, 54.7% of older adults with DM had cognitive impairment, 67.9% had arterial hypertension and 45.28% presented joint disease. 41.2% suffered falls, 68.52% visual problems and 87.3% tooth loss. Finally, 85.8% receive care but only 29.2% perceive improvement in their health. It is fundamental to develop integral programs and policies to care for older adults with DM. Copyright: © 2017 SecretarÍa de Salud

  8. Estudio observacional prospectivo con insulina detemir en pacientes con diabetes mellitus tipo 2 mal controlados que inician por primer vez tratamiento con insulina (estudio SOLVE

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    Domingo Orozco-Beltrán

    2016-02-01

    Conclusiones: En esta cohorte de pacientes con diabetes mellitus tipo 2 recientemente insulinizados, la insulina detemir (una vez al día mejoró el control glucémico, con baja incidencia de hipoglucemia y una reducción significativa del peso.

  9. Manejo práctico del paciente con diabetes mellitus en la Atención Primaria de Salud

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    Belkis Vicente Sánchez

    2011-12-01

    Full Text Available La diabetes mellitus es una enfermedad de primera importancia a nivel de salud pública en todo el mundo, por ser una de las enfermedades no transmisibles más frecuentes, y por la severidad y diversidad de sus complicaciones crónicas. Se realiza una revisión actualizada sobre el manejo de las personas con diabetes mellitus. Incluye definición, diagnóstico y clasificación, algoritmo para el pesquisaje de la enfermedad, conducta ante una persona con diabetes mellitus en la Atención Primaria de Salud, pilares de tratamiento y metas de control metabólico. Tiene como objetivo exponer elementos prácticos para el abordaje del paciente con diabetes mellitus tipo.Practical Management of Patients with Diabetes Mellitus in Primary Health CareDiabetes mellitus is a disease of major importance for public health throughout the world. This is mainly caused by its status as one of the most common non-communicable diseases and the severity and diversity of its chronic complications. An updated literary review on the management of patients with diabetes mellitus was conducted. It includes definition, diagnosis and classification, algorithm for disease’s screening, appropriate management of a patient with diabetes mellitus in primary health care, treatment pillars and goals for metabolic control. This review is aimed at exposing practical elements when approaching a patient suffering from diabetes mellitus.

  10. Papel del ejercicio físico en las personas con diabetes mellitus Role of physical exercise in persons presenting with diabetes mellitus

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    José Hernández Rodríguez

    2010-08-01

    Full Text Available INTRODUCCIÓN: el ejercicio físico constituye uno de los métodos más antiguos empleado en el tratamiento de la diabetes mellitus, y es uno de sus pilares fundamentales junto con la dietoterapia, la educación diabetológica y el empleo de fármacos normoglucemiantes o hipoglucemiantes. OBJETIVOS: discutir los aspectos más relevantes del papel del ejercicio físico en las personas con diabetes mellitus. DESARROLLO: se recomiendan los ejercicios aerobios en la diabetes mellitus, aunque actualmente el uso de ejercicios de resistencia con pequeñas cargas no está contraindicado en los diabéticos no complicados. Su práctica sistemática trae múltiples beneficios al paciente con diabetes mellitus, entre los que se destaca la mejoría del control metabólico, así como el retraso en la aparición de enfermedades cardiovasculares y la mejoría en el bienestar y la calidad de vida de aquellos que lo practican, entre otros. Además, en los no diabéticos puede ayudar a prevenir la enfermedad. El realizar ejercicio no está exento de riesgos, en particular en aquellos con complicaciones. La hipoglucemia es la complicación observada con mayor frecuencia, situación que puede ser prevenida ajustando el régimen terapéutico (dieta y fármacos. Está contraindicada la actividad física en diabéticos descompensados, porque empeora el estado metabólico. La práctica de deportes extremos de alta peligrosidad no es recomendada en los pacientes con diabetes mellitus. CONCLUSIONES: el ejercicio físico es un pilar fundamental en el tratamiento de la diabetes mellitus, incluso en su prevención.INTRODUCTION: physical exercise is one of the more ancient methods used in treatment of diabetes mellitus and it is one of its fundamental pillars together with dietary therapy, diabetes education and the use of normoglycemic and hypoglycemic drugs. OBJECTIVES: to discuss on the more relevant features of the physical exercise role in persons presenting with

  11. Espiritualidad e incertidumbre ante la enfermedad en personas con diabetes mellitus tipo 2

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    Gómez Palencia, Isabel Patricia

    2010-01-01

    Objetivo: Determinar la relación entre espiritualidad e incertidumbre presente en personas con situación crónica por diabetes mellitus tipo II. Metodología: abordaje cuantitativo de tipo correlacional de corte transversal, midiendo la espiritualidad con la escala de perspectiva espiritual de Reed, y la incertidumbre con la escala de Mishel. La muestra incluye 163 pacientes, distribuidos en la institución de la ESE Cartagena de Indias; y Fundación MEDICUS “Casa del diabético de Car...

  12. Riesgo coronario en pacientes con diabetes mellitus tipo 2

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    Andrés Eduardo Gallegos Cobo

    2017-09-01

    CONCLUSION: La estratificación del riesgo coronario elevado en pacientes con DM2 fueron frecuentes en este estudio comportándose de forma similar a otras casuísticas revisadas sobre este tema, repercutiendo de forma integral en la salud cardiovascular, ultimando hasta el momento no se ha implementado recomendaciones según estrategias en el servicio de Medicina Interna. Recomendando se realice estudios cuyo propósito es generar estrategias integrales para concientizar a los pacientes y al personal de salud sobre la necesidad de prevenir y controlar el riesgo coronario, y con ello disminuir los ingresos hospitalarios, costos económicos, las comorbilidades e incrementar la expectativa y calidad de vida de quienes la padecen.

  13. Edema macular por tratamiento con rosiglitazona en diabetes mellitus

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    Asensio-Sánchez, V.M.; Asensio-Sánchez, M.J.; Gómez-Ramírez, V.

    2010-01-01

    Caso clínico: Mujer de 61 años diabética tipo 2 de 7 años de evolución en tratamiento con insulina. Se añade rosiglitazona (4mg al día) para conseguir un control glucémico adecuado. Un mes después, la paciente presenta edema generalizado y pérdida de visión. El estudio fundoscópico mostró edema macular bilateral. En la exploración sistémica destacaban edemas periféricos. La rosiglitazona fue suspendida y la paciente fue tratada de forma conservadora, con resolución rápida de los edemas perifé...

  14. Estilo de vida actual de los pacientes con diabetes mellitus tipo 2

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    María Mercedes Ramírez-Ordoñez

    2011-12-01

    Full Text Available Se realizó un estudio descriptivo transversal con el objetivo principal de determinar el estilo de vida actual de los pacientes con diabetes mellitus tipo 2. Para la recolección de la información se utilizó el cuestionario IMEVID1. La población está conformada por 60 pacientes inscritos al programa de diabetes e hipertensión de una Institución Promotora de Salud (IPS de I nivel; como muestra se tuvo en cuenta 30 pacientes que asistieron sin falta al control de la diabetes a los cuales se les aplicó el instrumento. Las variables utilizadas son nutrición, actividad física, consumo de tabaco, consumo de alcohol, información sobre la diabetes, emociones, adherencia terapéutica y estilos de vida. Se concluye que con relación a la edad de los pacientes encuestados se obtiene que estos se encuentran entre dos etapas muy importantes del ciclo vital humano, adultez media y adultez tardía; el 80% de los pacientes encuestados presentaron prácticas de estilos de vida saludables, el cual ayuda a prevenir complicaciones con relación a su patología obteniendo de esta manera un mejor bienestar durante su vida y la evolución de la enfermedad.

  15. Diabetes mellitus

    NARCIS (Netherlands)

    Ahdi, M.; Gerdes, V. E.; Hoekstra, J. B.; Meesters, E. W.

    2012-01-01

    Currently there are over 740,000 patients with diabetes mellitus in the Netherlands, and this number will increase further in the coming years. Approximately 90% of patients has type 2 diabetes, a metabolic disorder that is often associated with obesity, hypertension and increased cholesterol

  16. Aspectos más recientes en relación con la diabetes mellitus tipo MODY Most recent aspects about type MODY diabetes mellitus

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    Ana Ibis Conesa González

    2012-08-01

    Full Text Available Antecedentes: la mejor comprensión fisiopatológica de la diabetes mellitus permite identificar diferentes tipos, entre ellos una variante monogénica denominada por sus siglas en inglés MODY (Maturity-Onset Diabetes of the Young. Objetivos: describir los aspectos fisiopatológicos, clínicos, diagnósticos y terapéuticos de los diferentes subtipos MODY. Desarrollo: los pacientes con diabetes tipo MODY presentan un comportamiento similar a la diabetes mellitus del adulto. Se caracteriza por una alteración genética autosómica dominante inherente y primaria a un defecto en la secreción de insulina. Hasta el momento actual se aceptan 9 subtipos de MODY. Los subtipos 1, 3, 4, 5 y 6 afectan a genes que codifican a factores nucleares de trascripción, y el subtipo 2 al gen que codifica a la enzima glucoquinasa. Se caracterizan clínicamente por cuadros que oscilan entre hiperglucemias permanentes, leves o moderadas, con buen pronóstico clínico, y pocas complicaciones, hasta cuadros de hiperglucemias mantenidas acompañadas de complicaciones crónicas precoces y graves. Conclusiones: las personas que padecen diabetes tipo MODY no son tan infrecuentes como se piensa. La correcta y temprana identificación de la enfermedad permitirá una acción terapéutica más racional y adecuada para brindar la posibilidad de mejor calidad de vida de estas personas.Background: a better physiopathological understanding of diabetes mellitus allows identifying its different types such as a monogenic variant called MODY (maturity-onset diabetes of the young. Objectives: to describe the physiopathological, clinical, diagnostic and therapeutic aspects of the different subtypes in MODY diabetes. Development: the patients with MODY diabetes behave similarly to those suffering diabetes mellitus in adults. It is characterized by inherited dominant autosomal genetic alteration which is primary to a defect in insulin secretion. Up to the present, 9 subtypes are accepted

  17. Calidad del hueso en mujeres de edad mediana con diabetes mellitus tipo 2 Bone quality in middle-aged females with type 2 diabetes mellitus

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    Alina Acosta Cedeño

    2008-04-01

    Full Text Available ANTECEDENTES: la osteoporosis y diabetes mellitus constituyen problemas de salud para la población senescente en general y para la mujer en particular. El descontrol metabólico y las lesiones microvasculares de la DM afectan todo el organismo, incluyendo el hueso. OBJETIVO: determinar la calidad del hueso en mujeres de edad mediana con diabetes mellitus tipo 2. MÉTODOS: estudio descriptivo-transversal, consistente en determinar la calidad del hueso en 30 mujeres con diabetes mellitus tipo 2, y 20 sin diabetes mellitus que constituyeron el grupo control. Se les realizó historia clínica, para precisar: edad, índice de masa corporal, circunferencia de cintura y actividad física; además, en las diabéticas: tiempo de evolución de la diabetes mellitus, glucemia en ayunas y posprandial de 2 h. La calidad del hueso se determinó mediante densitómetro LEXUS y se expresó como contenido mineral óseo y T-score en L2-L4 y el radio. Se utilizaron los criterios de la OMS para definir osteoporosis. Se emplearon estadígrafos descriptivos y correlaciones lineales. RESULTADOS: el 33 % de las pacientes con diabetes mellitus tipo 2 tuvo osteoporosis en el radio, y el 3,3 % en L2-L4, lo que ocurrió en el 75 y el 30 % respectivamente de las no diabéticas. El contenido mineral óseo en: L2-L4 de las diabéticas fue 0,561 g/cm² yen el radiode 0,358 g/cm², mientras en las no diabéticas fue 0,285 y 0,313 g/cm² respectivamente (p de 18,5 kg/m² de superficie corporal (sc y la circunferencia de cintura > de 88 cm con el contenido mineral óseo, y asociación negativa entre el T-score en el radio y la glucemia en ayunas ³ a 7mmol/L, y entre el tiempo de evolución > de 5 años con el contenido mineral óseo en L2-L4 (pBACKGROUND: osteoporosis and diabetes mellitus are health problems for the aging population in general and for females in particular. The metabolic decontrol and the microvascular lesions of DM affect the whole organism, including bones

  18. Diabetes mellitus

    OpenAIRE

    Skiadopoulos, Dionysios

    2013-01-01

    This theses on Diabetes Mellitus aims at giving an insight at various aspects of this chronic disease and the risk factors that lead to it; the varius ways it develops in the human body; the old and new approaches to treatment, both from a pharmacological and a non- pharmacologiacal point of view; ways to prevent and to manage the diabetes complications; how to improve the live of the diabetic patients who are faced with not only physical but also psychological problems; statistical data from...

  19. Celulitis orbitaria bilateral con endoftalmitis en una paciente con reciente diagnóstico de diabetes mellitus tipo 2

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    Lesley Farrell González

    2014-07-01

    Full Text Available Se presentó una mujer de 74 años al servicio de urgencias del HRAEBI, ISSSTE, el día 2 de septiembre de 2010 con datos de desequilibrio hidroelectrolítico, hipotensión y conjuntivitis bilateral. Sus signos vitales durante su estancia en urgencias fueron: tensión arterial, 80/40 mmHg; temperatura, 38.5 °C; frecuencia respiratoria, 22 rpm; frecuencia cardíaca 89 lpm Se interconsulta al servicio de Oftalmología quienes diagnosticaron celulitis orbitaria bilateral, con no percepción de luz en ambos ojos e igualmente ausencia de reflejos pupilares. Se inició tratamiento con antibióticos intravenosos y se solicitó tomografía computarizada de órbitas y cerebro. Se internó para estabilizar su estado general; durante su estancia se diagnosticó diabetes mellitus y estado inmunosupresivo por datos de candidiasis oral y otros síntomas. La tomografía mostró celulitis orbitaria bilateral con formación de abscesos orbitarios, sin datos de proceso infeccioso a nivel bucal o de senos paranasales. La evolución de la celulitis fue tórpida a pesar de la terapia antibiótica cuádruple (cefotaxima, vancomicina, metronidazol y clindamicina; posteriormente imipenem, clindamicina y vancomicina con desarrollo de endoftalmitis bilateral por lo cual fue necesario eviscerar ambos ojos. Se tomó cultivo directo del vítreo y 3 días después se encontró como germen causal Klebsiella pneumoniae.

  20. Diabetes mellitus

    International Nuclear Information System (INIS)

    Ogawa, Junichiro; Ito, Chikako

    1992-01-01

    It is believed that the pancreas is low sensitive to radiation. In this chapter, the effect of radiation on the pancreas is discussed in the light of the radiosensitivity of the pancreas in animal experiments and the occurrence of diabetes mellitus in A-bomb survivors. In an experiment on the whole-body irradiation with 800 rad using rats, a decrease in insulin secretion itself has not been noted, although a decrease in blood insulin and an increase in glucagon were associated with transiently increased blood glucose. In other studies, there was neither histologically nor endocrinologically abnormal findings due to several hundreds rad of radiation in the acute stage. For A-bomb survivors, blood levels of insulin tended to be slightly increased in the 40-59 age group of A-bomb survivors exposed at ≤1.5 km than those exposed at ≥3.0 km; and in the other age groups, there was no tendency for decreased blood levels of insulin. The ABCC-RERF Adult Health Study data (1958-1960) has revealed that there is no statistically significant correlation between the prevalence of diabetes mellitus and A-bomb radiation; nor has this been noted in any other study. Neither the prevalence of diabetes mellitus nor its complications is found to be independent upon distance from the hypocenter. (N.K.)

  1. ESTILOS DE PERSONALIDAD Y ADHERENCIA AL TRATAMIENTO EN PACIENTES CON DIABETES MELLITUS/ PERSONALITY STYLES AND ADHERENCE TO TREATMENT IN PATIENTS WITH DIABETES MELLITUS

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    Elodia Elisabeth Granados*

    2010-09-01

    Full Text Available RESUMENEl propósito de la investigación fue examinar la contribución de la variable personalidad en las conductas de adherenciaal tratamiento en pacientes con diabetes. Se trabajó a partir de un diseño: transversal con metodología descriptivo-correlacionaly triangulación de datos cualitativos obtenidos mediante entrevistas. Participantes: muestra no probabilística de 19 sujetos,(10 varones y 9 mujeres con diabetes mellitus tipo 1 o tipo 2, con más de 5 años de evolución de la enfermedad. Se les aplicócuestionario MIPS de estilos de personalidad (Millon, 1997, cuestionario sobre auto-percepción de adherencia al tratamientode la diabetes, y entrevista semidirigida. El análisis de los datos se realizó a partir del análisis de correspondencias múltiples(ACM utilizando el paquete informático XLSTAT. Con las entrevistas se procedió a una codificación temática. El ACMevidenció escasa interacción entre los niveles de adherencia y estilos de personalidad, del análisis de los casos atípicos seobtuvo que, la interacción de dos categorías centrales: conocimientos sobre la enfermedad y conocimientos sobre sí mismo,explican el alto nivel de adherencia.ABSTRACTThe purpose of the research was to examine the contribution of personality variable in the behavior of adherence totreatment in patients with diabetes. We worked from a design: Cross-sectional descriptive-correlational methods andtriangulation of qualitative data obtained through interviews. Participants: nonrandom sample of 19 subjects (10 men and 9women with diabetes mellitus type 1 or type 2, with more than 5 years of disease progression. MIPS questionnaire wasapplied personality style (Millon, 1997, questionnaire on self-perception of adherence to treatment of diabetes, andsemistructured interview. The data analysis was performed from multiple correspondence analysis (MCA using the softwarepackage XLSTAT. The interviews carried out a thematic coding. The ACM showed little

  2. Pessoas com Diabetes Mellitus: suas escolhas de cuidados e tratamentos Personas con Diabetes Mellitus: sus opciones de atención y tratamiento People with Diabetes Mellitus: their care and treatment choices

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    Denise Guerreiro Vieira da Silva

    2006-06-01

    Full Text Available Estudo fundamentado na pesquisa qualitativa, na perspectiva interpretativista. Teve como objetivo conhecer o itinerário terapêutico de pessoas com diabetes mellitus na busca de cuidados e tratamentos nos diferentes subsistemas de cuidado a saúde. Os dados foram obtidos através de entrevistas em profundidade e grupos focais. A análise permitiu identificar as modalidades terapêuticas, a avaliação do cuidado e do tratamento à saúde e o percurso terapêutico nos três subsistemas. O Diabetes Mellitus requer mudanças no processo de viver. A pessoa realiza várias modalidades terapêuticas até perceber aquela ou aquelas que lhes são mais adequadas, tanto do ponto de vista do bem estar físico, quanto de como esse cuidado ou tratamento interfere em seu cotidiano.Estudio basado en el abordaje de investigación cualitativa, en la perspectiva interpretativa. Tuvo como objetivo conocer el itinerario terapéutico de las personas con Diabetes Mellitus en la busca de la atención y tratamientos en los diferentes subsistemas de atención a la salud. Los datos fueron obtenidos a través de entrevistas en profundidad y grupos focales. Fueron identificadas las modalidades terapéuticas, la evalución del cuidado y del tratamiento y el recorrido terapéutico en los tres subsistemas. Percibimos que el mayor impacto de vivir con diabetes mellitus es que la persona necesita revisar su proceso de vivir. Así, la persona circula por varias modalidades terapéuticas hasta percibir aquellas que les sean más convenientes, tanto desde el punto de vista del bienestar físico, como de la forma en que el tratamiento se integra a su cotidiano.Study based on qualitative research, from an interpretative perspective. Its objective was to understand the therapeutic itinerary of people with Diabetes Mellitus who search for different care and treatments within the different subsystems of health care. The data was collected through in-depth interviews and focus groups

  3. Asociación de la microalbuminuria con la disfunción ventricular izquierda en personas normotensas con diabetes mellitus tipo 1 Microalbuminuria and its association with left ventricular dysfunction in normotensive subjects presenting with type 1 diabetes mellitus

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    Manuel Emiliano Licea Puig

    2009-04-01

    Full Text Available ANTECEDENTES: la disfunción ventricular izquierda es una complicación frecuente en las personas con diabetes mellitus 1. OBJETIVO: determinar si la excreción urinaria de albúmina se asocia a la presencia de disfunción ventricular izquierda en personas normotensas con diabetes mellitus 1 de largo tiempo de evolución. MÉTODOS: se realizó un estudio transversal y descriptivo en 80 diabéticos normotensos tipo 1 con 10 años o más de evolución de la diabetes mellitus 1, atendidos consecutivamente en nuestro centro, en edades entre los 15 y los 40 años. Se excluyeron otras enfermedades o condiciones que provoquen por sí mismas disfunción ventricular izquierda y proteinuria. Se estudió: edad, sexo, índice de masa corporal, hábito de fumar, presión arterial, evolución de la diabetes mellitus 1, retinopatía diabética, nefropatía diabética incipiente, glucemia en ayunas y posprandial de 2 h, hemoglobina glucosilada (HbA1, excreción urinaria de albúmina de 24 h, creatinina, electrocardiograma y ecocardiograma modo M bidimensional con Doppler pulsado. RESULTADOS: se comprobó disfunción ventricular izquierda en el 26,3 % y alteraciones estructurales en el 16,2. La frecuencia de nefropatía diabética incipiente fue mayor (pBACKGROUNDS: left ventricular dysfunction is a frequent complication in persons presenting with type 1 diabetes mellitus. OBJECTIVE: to determine if albumin urinary excretion is associated with the presence of left ventricular dysfunction (LVD in normotensive persons presenting with type diabetes mellitus of a long evolution. METHODS: we made a descriptive and cross-sectional study in 80 normotensive type 1 diabetic patients aged between 15 and 40 with a ³10 years of type 1 diabetes mellitus evolution seen in a consecutive way in our service. Other diseases were excluded or those conditions provoking per se left ventricular dysfunction and proteinuria. Study includes: age, sex, body mass index (BMI, smoking

  4. Crecimiento y desarrollo de niños y jóvenes con diabetes mellitus tipo 1

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    Enrique Rotemberg Wilf

    Full Text Available Resumen La diabetes mellitus es un síndrome metabólico que se caracteriza por hiperglucemia con alteración en el metabolismo de los carbohidratos, proteínas y grasas, causada por deficiencias en la producción o en la utilización de la insulina. Es la enfermedad endocrinometabólica más frecuente de la infancia y adolescencia. La diabetes tipo 1 es una condición crónica debido a la destrucción de las células beta de los islotes de Langerhans del páncreas por enfermedad autoinmune o sin causa conocida. El crecimiento y desarrollo general y cráneo facial del individuo van a estar influenciados por distintos factores que actúan interrelacionados. Los profesionales de la salud deben controlar la evolución del niño con diabetes 1 especialmente durante la pubertad. Es probable encontrar diferencias de crecimiento y desarrollo entre jóvenes con eficaz o con pobre control glucémico, en especial si la enfermedad es de inicio prepuberal y si es o no diagnosticada en forma precoz. La diabetes mellitus tipo 1 puede afectar la salud buco-dental de niños y adolescentes, con posibles consecuencias en la vida adulta

  5. Adaptación en Pacientes con Diabetes Mellitus Type 2, Según Modelo de Roy

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    Lazcano Ortíz, Margarita; Salazar Gonzalez, Bertha C

    2009-01-01

    Objetivo. Determinar la influencia entre estímulos focales y contextuales, y la adaptación fisiológica y psicosocial en personas con diabetes Mellitus Tipo 2 (DMT2). Material y método. El diseño fue descriptivo, transversal, predictivo. El muestreo fue probabilístico, sistemático. La muestra con 200 participantes de ambos géneros de 30 a 65 años, se determinó para un 95% de confianza, con una potencia de prueba de 90%. Resultados. Los resultados mostraron que el tiempo desde diagnóst...

  6. Adaptación en pacientes con diabetes Mellitus Tipo 2, según Modelo de Roy

    OpenAIRE

    Margarita Lazcano-Ortiz; Bertha Cecilia Salazar-González

    2009-01-01

    Objetivo. Determinar la influencia entre estímulos focales y contextuales, y la adaptación fisiológica y psicosocial en personas con diabetes Mellitus Tipo 2 (DMT2). Material y método. El diseño fue descriptivo, transversal, predictivo. El muestreo fue probabilístico, sistemático. La muestra con 200 participantes de ambos géneros de 30 a 65 años, se determinó para un 95% de confianza, con una potencia de prueba de 90%. Resultados. Los resultados mostraron que el tiempo desde diagnóstico expli...

  7. Intervención educativa en adultos mayores con diabetes mellitus en Guatemala

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    José Manuel Contreras Tejeda

    2014-08-01

    Full Text Available Se realizó un estudio de intervención comunitaria, con el objetivo de incrementar los conocimientos en pacientes diabéticos adultos mayores, pertenecientes al Departamento Alta Verapaz, Cobán, Guatemala; en el período comprendido desde junio de 2011 hasta junio de 2012. El universo de estudio estuvo constituido por los pacientes diabéticos dispensarizados por el médico y la enfermera en el área periférica, conformándose la muestra con 46 de ellos, a los cuales se les evaluó el grado de conocimientos previo y posterior a la aplicación de la intervención para modificar estilos de vida, empleando para ello técnicas participativas. Para obtener la información se revisaron las historias clínicas individuales, se realizaron entrevistas y se aplicaron cuestionarios a los pacientes, antes y después de aplicadas las técnicas educativas. Los resultados fueron procesados por métodos estadísticos. En la muestra predominaron los pacientes con diabetes mellitus tipo II. Después de la intervención hubo un incremento en las respuestas correctas en un 63.04%, haciéndose más marcado a medida que aumenta el nivel de escolaridad y en los que tienen más de diez años de evolución de la enfermedad. El estado nutricional se mejoró en un 50%. Se logró un mejor control de las complicaciones crónicas, así como del control metabólico en un 78.26%. Las charlas educativas en la comunidad resultaron efectivas para la incorporación de elementos educativos que incidieron en el mejor autocuidado de los pacientes diabéticos

  8. Respuesta adaptativa a la diabetes mellitus y su relación con el envejecimiento Adaptative response to diabetes mellitus and its relation to aging

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    Victor Pérez Martínez

    2004-08-01

    Full Text Available Se seleccionó una muestra de 130 pacientes diabéticos entre 60 y 75 años de edad, pertenecientes al Policlínico Docente "Ana Betancourt". Fueron estudiados con el objetivo de evaluar su respuesta adaptativa a la enfermedad, así como otros factores que influyen en el proceso de envejecimiento. Se comprobó la existencia de un patrón común de respuesta a la diabetes mellitus en más del 90 % de los pacientes, caracterizado por la valoración de la enfermedad como un padecimiento severo, la existencia de barreras para el cumplimiento del tratamiento, una tendencia a mejorar la conducta de salud y un aceptable funcionamiento de las redes de apoyo social. La respuesta adaptativa a la diabetes mellitus se comportó como deficiente en la mayoría de los pacientes , pero la relación directa entre esta y los sistemas de apoyo social, cuyo funcionamiento resultó estable, unido al bajo índice de depresión constatado, pueden utilizarse como recursos para el mejoramiento de dicha respuesta hacia niveles de adaptación satisfactorios.A sample of 130 diabetic patients aged 60-75 from "Ana Betancourt" Teaching Polyclinic was selected to conduct a retrospective study.. They were studied in order to evaluate their adaptative response to the disease, as well as other factors influencing on the aging process. It was proved the existance of common pattern of response to diabetes mellitus in more than 90 % of the patients, characterized by the assessment of the disease as a severe ailment, the existance of barriers for following the treatment, a trend towards improving health behavior and an acceptable functioning of the social support networks. The adaptative response to diabetes mellitus was deficient in most of the cases, but the direct relation between this and the social support systems, whose functioning was steady, together with the low depression index observed, may be used as resources to take this answer to satisfactory adaptation levels.

  9. Comportamiento del infarto agudo del miocardio en personas con diabetes mellitus de la provincia Granma Situation of the acute myocardial infarction in persons with diabetes mellitus in Granma province

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    Eduardo René Valdés Ramos; Marjoris Rivera Chávez; Niurka Bencosme Rodríguez

    2012-01-01

    Antecedentes: la diabetes mellitus, además de ser un factor de riesgo para el infarto agudo del miocardio, parece conferir per se un peor pronóstico en los pacientes con esta entidad. Objetivo: evaluar el comportamiento del infarto agudo del miocardio en personas con diabetes mellitus de la provincia de Granma. Métodos: se realizó un estudio transversal y descriptivo con 159 pacientes que ingresaron en la Unidad de Cuidados Intensivos Coronarios del Hospital "Carlos Manuel de Céspedes", de Ba...

  10. Frecuencia de maculopatía en pacientes con diabetes mellitus tipo 2: Reporte preliminar Frequency of maculopathy in patients with type 2 diabetes mellitus: A preliminary report

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    Harberth Fernández Leyva

    2002-08-01

    Full Text Available Se realizó un estudio transversal de 542 pacientes con diabetes mellitus tipo 2 (DM2 ICA- reclutados consecutivamente en el Centro de Atención al Diabético. Se les hizo historia clínica completa y examen oftalmológico: biomicroscopia y oftalmoscopia (directa e indirecta y examen con lente de 90 Dp. Se determinó glucemia en ayunas, 2 h después del desayuno y del almuerzo, hemoglobina glucosilada (HbA1 y excreción urinaria de albúmina (EUA. La maculopatía se clasificó en exudativa, edematosa e isquémica, y se relacionó con el sexo, hábito de fumar, tratamientos de la DM, edad actual, edad al comienzo de la enfermedad, presión arterial y las variables bioquímicas: glucemia en ayunas, posprandiales, HbA1 y EUA. Se excluyó la nefropatía clínica (EUA ³ 300 mg/L. Se consideró DM2 de reciente presentación cuando el diagnóstico clínico era menor de 6 meses. Padecían algún tipo de maculopatía 95 (17,5 % pacientes: 49 (9,0 %, formas exudativas; 29 (5,3 %, edematosas y 17 (3,2 %, isquémicas. No se hallaron diferencias significativas con el sexo, hábito de fumar o tratamientos utilizados, al dividirlos según la presencia o no de maculopatía. La duración de la DM fue de 12,4 ± 9,45 años para los pacientes con maculopatía, con diferencia estadísticamente significativa (p A cross-sectional study was conducted among 542 patients with ICA-type 2 diabetes mellitus consecutively recruited at the Diabetic Care Center. A complete medical history and an ophthalmological examination: biomicroscopy and ophthalmoscopy (direct and indirect and examination with lens of 90Dp were made. Fasting glycaemia, 2 hours after breakfast and lunch, glycosilated haemoglobin (HbA1 and urinary albumin excretion (UAE were determined. Maculopathy was classified as exudative, edematous and ischaemic and it was related to sex, smoking habit, treatments of DM, present age, age at the onset of the disease, arterial pressure and biochemical variables, such

  11. Dislipidemia y microalbuminuria en niños con diabetes mellitus de tipo 1 Dyslipidemia and microalbuminuria in children presenting with type 1 diabetes mellitus

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    Alexander García Cabreja

    2009-03-01

    Full Text Available INTRODUCCIÓN. La diabetes mellitus de tipo 1 es una enfermedad autoinmunitaria que se caracteriza por una deficiencia absoluta de la producción de insulina, alteraciones del metabolismo de la glucosa, los lípidos y las proteínas. El objetivo de nuestra investigación fue conocer la relación entre dislipidemia y lesión renal diabética, expresada por la presencia de microalbuminuria. MÉTODOS. Se estudiaron 52 niños con diabetes mellitus de tipo 1, edades de 9 a 15 años y 2 años o más de duración de la enfermedad. A todos se les realizó lipidograma en ayunas que incluyó análisis de triglicéridos, colesterol total, colesterol de las lipoproteínas de baja densidad y colesterol de las lipoproteínas de alta densidad. Se realizaron pruebas de microalbuminuria mediante radioinmunoanálisis para la albúmina humana en orina y también filtrado glomerular. RESULTADOS. Se observó dislipidemia en 30 pacientes (57 % y disminución del colesterol de lipoproteínas de alta densidad en todos los pacientes dislipidémicos. Se constató un aumento del colesterol de lipoproteínas de baja densidad en 27 casos (51,9 %; el colesterol total estaba elevado en 12 (23 % y se comprobó hipertrigliceridemia solo en 4 pacientes (7,6 %. Veintiuno de los 30 niños dislipidémicos (70 % tenían microalbuminuria. Se encontró que los pacientes con dislipidemia tenían mayor porcentaje de microalbuminuria, pero éste no fue significativo. En todos los pacientes con dislipidemia se observó una disminución del colesterol de lipoproteínas de alta densidad. La dislipidemia tuvo correlación positiva con la duración de la diabetes, pero no con el sexo. CONCLUSIONES. En la diabetes mellitus de tipo 1, el colesterol total y los triglicéridos no ofrecen información suficiente y es necesario realizar estudios del colesterol de lipoproteínas de alta densidad para poder pronosticar una futura lesión renal. No sólo el control glucémico, sino también el control

  12. Prevalencia de desnutrición en ancianos hospitalizados con diabetes mellitus

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    Sanz París, Alejandro; García, José María Hernández; Gómez-Candela, Carmen; Burgos, Rosa Romero; Martín, Ángela O.; Matía, Pilar

    2013-01-01

    Background & aims: Malnutrition prevalence is unknown among elderly patients with diabetes mellitus. Our objectives were to determine malnutrition prevalence in elderly in patients with diabetes, and to describe their impact on prognosis. Methods: An observational multicenter study was conducted in 35 Spanish hospitals. Malnutrition was assessed with the Mini Nutritional Assessment (MNA) tool. Patients were followed until discharge. Results: 1,090 subjects were incl...

  13. Biomecánica del pié diabético: estudio experimental de pacientes con Diabetes Mellitus Tipo I con y sin neuropatía periférica

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    Pérez Verdún, Miguel Ángel

    2014-01-01

    La prevalencia de pacientes con diabetes mellitus tipo I en España supone del 10 al 15% del total de los pacientes con diabetes. Algunos estudios apoyan la correlación entre alteraciones biomecánicas del pie y el desarrollo neuropático en diabetes. Objetivo Principal: Relacionar las alteraciones biomecánicas del pie con la presencia de neuropatía periférica de miembros inferiores en pacientes con diabetes mellitus tipo 1. Objetivos secundarios: Conocer los patrones de presión plantar, sup...

  14. Adherencia al tratamiento nutricional en pacientes con diabetes mellitus tipo 2 que asisten a un programa educativo

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    Mariela A. Carvajal

    2017-01-01

    El objetivo de este estudió fue evaluar la adherencia al tratamiento nutricional por medio de la hemoglobina glicosilada en pacientes con diabetes mellitus tipo 2 que asistieron a un programa educativo en diabetes en la ciudad de Guatemala, así como evaluar los principales factores que influyen en ella. Se realizó un estudio de tipo prospectivo, longitudinal, experimental, pareado de intervención no medicamentosa. Se utilizó la prueba de Morinsky-Green Levine para evaluar la adherencia al tra...

  15. Alimentación de niños con diabetes mellitus tipo 1 con respecto a las recomendaciones

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    San Martín Jiménez, Rocío

    2014-01-01

    Introducción: La diabetes tipo 1 es una enfermedad crónica prevalente en la infancia, siendo unos de los pilares fundamentales de su tratamiento la alimentación. Diseñamos un estudio para valorar el grado de cumplimiento de las recomendaciones nutricionales de los pacientes pediátricos con diabetes tipo 1. Diseño y métodos. Estudio observacional transversal de 50 niños y adolescentes con diabetes tipo 1, que acuden al Hospital Clínico Universitario de Valladolid. La ingesta fue recogida me...

  16. Adaptación en pacientes con diabetes Mellitus Tipo 2, según Modelo de Roy

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    Margarita Lazcano-Ortiz

    2009-01-01

    Full Text Available Objetivo. Determinar la influencia entre estímulos focales y contextuales, y la adaptación fisiológica y psicosocial en personas con diabetes Mellitus Tipo 2 (DMT2. Material y método. El diseño fue descriptivo, transversal, predictivo. El muestreo fue probabilístico, sistemático. La muestra con 200 participantes de ambos géneros de 30 a 65 años, se determinó para un 95% de confianza, con una potencia de prueba de 90%. Resultados. Los resultados mostraron que el tiempo desde diagnóstico explicó la adaptación fisiológica F (1,198 = 9,18, p = ,003. Se observó efecto entre complicaciones y adaptación psicosocial F (4,195 = 4,97, p = ,001, con un coeficiente de determinación del 74%. Los estímulos contextuales influyeron en la adaptación fisiológica y psicosocial, F (6,193 = 2,89, p = ,010, y F (6, 193 = 2,41, p = ,029. Conclusiones. Los resultados de este estudio permiten sugerir relaciones entre las proposiciones teóricas propuestas y derivadas del Modelo de Adaptación de Roy, particularmente entre los estímulos y la adaptación fisiológica y psicosocial en pacientes con diabetes Mellitus Tipo 2.

  17. Plan de Cuidados Estandarizado de Enfermería para pacientes con Diabetes Mellitus tipo 2 en la Atención Primaria

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    Tejido Ruiz-Ogarrio, Andrea Elisa

    2015-01-01

    Siendo la Diabetes Mellitus una de las enfermedades crónicas con más prevalencia mundial y con una incidencia aumentada en los últimos años, se ha visto necesario la estructuración de un Plan de Cuidados Estandarizado de Enfermería en Atención Primaria. Con este Plan de Cuidados, se conseguiría frenar el progreso de la enfermedad en pacientes diagnosticados de Diabetes Mellitus tipo 2, enfermedad generalmente asociada a personas en edad adulta con sobrepeso, por lo que la consulta de enfermer...

  18. Nivel de conocimientos sobre la enfermedad en los adultos mayores con diabetes mellitus tipo 2 Level of knowledge concerning diabetes mellitus type-2 in the elderly

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    María de la C Casanova Moreno

    2011-06-01

    Full Text Available Se realizó una investigación epidemiológica, descriptiva y transversal, con el objetivo de determinar el nivel de conocimientos sobre diabetes mellitus en los adultos mayores con diabetes tipo 2 durante el año 2010, en el área de salud Hermanos Cruz de la provincia de Pinar del Río. Se incluyeron 91 pacientes diabéticos tipo 2 que recibieron el servicio de atención integral al diabético de ambos sexos y en las edades de 60 y más años (n=91. Para determinar el nivel de conocimientos se aplicó una encuesta diseñada por los especialistas del Centro Provincial de Promoción y Educación para la Salud de la provincia; con los datos obtenidos se confeccionó una base de datos utilizando el programa EpiInfo 2002. Se hizo uso de la estadística descriptiva, los datos para su análisis fueron reflejados en cuadros de distribución de frecuencias y gráficos. Predominó el sexo femenino, la enfermedad crónica no transmisible que más se asoció fue la hipertensión arterial. El nivel de conocimientos fue insuficiente en todos los grupos según el tiempo de evolución de la enfermedad, lo mismo sucedió con los pacientes con complicaciones crónicas. Los diabéticos adultos mayores necesitan fortalecer la educación diabetológica para mejorar los conocimientos sobre la enfermedad y tener una mejor calidad de vida.An epidemiological, descriptive and cross-sectional research was carried out in 2010 with the objective of determining the level of knowledge concerning diabetes mellitus type-2 in the elderly suffering from this disease at "Hermanos Cruz" health area, Pinar del Rio. Ninety one (91 diabetic- type-2 patients attended to the comprehensive care service for both sexes, ages of 60 years old and older (n=91 participated in the study. To determine the level of knowledge a survey was applied, this was prepared by the specialists of the Provincial Center for Health Promotion and Education, arranging a database supported on these results and

  19. Evaluación integral de la sensibilidad en los pies de las personas con diabetes mellitus tipo 2

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    Valentina Rivas Acuña

    2017-01-01

    Full Text Available Introducción: Actualmente la diabetes mellitus tipo 2 es considerada una epidemia en el mundo, es uno de los problemas de mayor trascendencia, por su alta prevalencia como por su enorme repercusión social y económica, por tal motivo el propósito del estudio fue evaluar de manera integral la sensibilidad en los pies de las personas con diabetes mellitus tipo 2, de Villahermosa, Tabasco, México. Materiales y Métodos: El diseño fue descriptivo correlacional, la muestra fue de 198 personas. Se utilizó el Test del Michigan Neuropathy Screening con monofilamento de Semme Weinstein, Diapasón, temperatura frío/calor y reflejo Aquileo. Resultados y Discusión: El sexo femenino predominó con un 70.2% y el 29.8% hombres, el promedio de edad fue 56.44 años y 12.34 años promedio con la enfermedad. El 46% registró síntomas neuropáticos moderados, 26.3% graves; el 65.7% riesgo de neuropatía positiva (40.9% mujeres y 24.8% hombres, 41.1% con pérdida de sensibilidad moderada y 29.3% sensibilidad normal; el 74.7% tiene un control glucémico deficiente. Los factores de riesgo detectados con mayor prevalencia fueron helomas, hiperqueratosis y deformidades. Conclusiones: Existe una correlación significativa entre la pérdida de la sensibilidad con los años con la enfermedad, con la hiperglucemia y síntomas de neuropatía, la pérdida de sensibilidad en mujeres es de moderada a grave y en los hombres la pérdida de la sensibilidad es moderada. Cómo citar este artículo: Rivas V, Mateo Y, García H, Martínez A, Magaña M, Carrillo R.  Evaluación integral de la sensibilidad en los pies de las personas con diabetes mellitus tipo 2. Rev Cuid. 2017; 8(1:1423-32. http://dx.doi.org/10.15649/cuidarte.v8i1.348

  20. Respuesta sexual de la mujer de edad mediana con diabetes mellitus Sexual response of middle-aged women with diabetes mellitus

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    Adriana Agramonte Machado

    2002-12-01

    Full Text Available Se realizó un estudio descriptivo transversal para describir las características de la respuesta sexual de la mujer con diabetes mellitus (DM, se emplearon cuestionarios autoadministrados (Sexualidad y el Inventario de Depresión de Beck y fueron evaluadas 180 mujeres de la mediana edad (90 con DM y 90 sin DM registradas en 31 consultorios de médicos de familia de 3 policlínicos del municipio Plaza de la Revolución. En cada mujer se precisó: datos generales necesarios para caracterización sociodemográfica, etapa climatérica, presencia de depresión y frecuencia de relaciones sexuales (RS, nivel de satisfacción con las RS, deseo y excitación sexual y orgasmos, y en las mujeres con DM, las características de la enfermedad y la auto percepción de la influencia de la misma sobre su sexualidad. Se comprobó que las mujeres con DM tenían: 1. Niveles menores de deseo y excitación sexual y mayor frecuencia de trastornos sexuales, 2. Mayor frecuencia de orgasmo, 3. Parejas sexuales con mayor frecuencia de disfunciones sexuales, 4. En su mayoría están satisfechas con la frecuencia de sus RS. En conclusión, la respuesta sexual de la mujer con DM difiere cuantitativamente de la mujer sin DM, se necesitarán nuevos estudios que permitan profundizar en las causas de estas diferencias.A cross-sectional descriptive study was conducted to describe the characteristics of the sexual response of women with diabetes mellitus (DM. Self-administered questionnaries (Sexuality and Beck's Depression Inventory were applied. 180 middle-aged women (90 with DM and 90 without DM registered in 31 family physician offices from 3 polyclinics of Plaza de la Revolución municipality were evaluated. The following information was obtained for each woman: general data necessary for the sociodemographic characterization, climacteric stage, presence of depression and frequency of sexual relations (SR, level of satisfaction with SR, sexual desire and excitement, and

  1. Modelo de manejo de casos en pacientes con diabetes mellitus tipo 2 Case management model in patients with type 2 diabetes mellitus

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    María Guadalupe Martínez de Dávila

    2006-03-01

    Full Text Available Objetivo: Implementar el modelo de manejo de casos y evaluar su efectividad en pacientes hospitalizados con diabetes mellitus tipo 2 Metodología: Muestra de 17 pacientes hospitalizados con diabetes mellitus tipo 2 para dos grupos, experimental y control. Etapas del estudio: a selección de pacientes y capacitación del equipo multidisciplinario, b intervención multidisciplinaria y c seguimiento en el hogar. Resultados: Grupo experimental: media de días estancia hospitalaria de 4.88. Sólo 11.8% de los pacientes tuvo un reingreso hospitalario en los seis meses posteriores al egreso. Media de hemoglobina glucosilada al ingreso al hospital 11.45%; al finalizar la intervención 8.84%, la prueba de comparación de medias t de Student reportó diferencia significativa (p=.001. Grupo control: media de días estancia de 6.24. En los siguientes seis meses 35.3% tuvieron de uno a dos reingresos. Conclusiones: El grupo experimental reportó menores días estancia y reingresos hospitalarios, mayor conocimiento y acciones de autocuidado para el tratamiento de la enfermedad, mayor involucramiento de la familia en el cuidado y mejor control glucémico a través de la hemoglobina glucosilada.Aim: To implement the Case Management Model and to assess its effectiveness in patients with type 2 diabetes mellitas. Methodology: Two seveenteen patients groups were sampled. One was experimental and the second was a control group Study stages: a selection of patients and training of the multi-disciplinary team, b multi-disciplinary intervention, c follow-up at home. Results: Experimental group: mean days of hospital stay were 4.88. Only 11.8% of patients had one hospital readmission within the six months after the discharge. Mean of glycosilated hemoglobin at hospital admission: 11.45%.At the end of intervention: 8.84%. The t student comparison of means showed a significant difference (p= 001. Control group: mean days of stay was 6.24. In the following six months 35

  2. DIABETES MELLITUS Y SU ASOCIACIÓN CON DETERIORO COGNITIVO Y DEMENCIA

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    DR. Gonzalo Muñoz A.

    2016-03-01

    Se han descrito alteraciones en todos los dominios cognitivos, sin embargo velocidad psicomotora y atención son los más comúnmente vinculados a la diabetes. Concluimos que la diabetes tiene como órgano blanco el cerebro y enfatizamos la importancia del estudio neuropsicológico en pacientes con larga historia de la enfermedad y en aquellos donde pudiera existir un trastorno cognitivo que puede condicionar la adherencia al tratamiento.

  3. Prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2

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    Dulman O. Pineda-De Paz; Mario R. Pineda-De Paz; Yu L. Lee-Tsai; Clara E. Chang; Lissette C. Torres-Salazar; Luis C. Barrios-Lupitou

    2018-01-01

    Resumen: Introducción: La enfermedad cardiovascular es la causa principal de muerte en pacientes con diabetes mellitus. La prevalencia de cardiopatía isquémica asintomática es más alta en pacientes diabéticos que en no diabéticos y se asocia a peor pronóstico. Objetivo: Identificar la prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2 en un hospital de tercer nivel de atención de Guatemala y analizar la posible asociación de dicha enfermedad con carac...

  4. Diabetes mellitus tipo 1: posible relación con la interrupción precoz de la lactancia materna

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    Dalila Teixeira Leal

    2012-12-01

    Full Text Available Introducción: La dieta es importante en la patogénesis de la diabetes tipo 1, los estudios indican una fuerte asociación entre la exposición temprana a la leche de vaca y la aparición de esta enfermedad. Objetivo: Verificar la existencia de la relación entre el destete precoz de la lactancia materna, la exposición a otras leches antes de seis meses de vida y el desarrollo de diabetes mellitus tipo 1. Materiales y Métodos: Investigación cuantitativa, a los padres respecto a los niños y adolescentes con diabetes tipo 1 que se registraron en el Departamento de Control de la Presión Arterial, Diabetes y Obesidad del Departamento Municipal de Salud de Juiz de Fora com una muestra total de 89 participantes. El instrumento utilizado para la recolección de datos fue un cuestionario estructurado aplicado a estos padres, los sujetos de la investigación fueron de ambos sexos y de todas las razas. Cabe señalar que el origen de esta investigación son los usuarios de los servicios de Diabetes Mellitus tipo 1, pero sólo los padres o tutores fueron entrevistados.Resultados: Se presentan datos sobre la caracterización de la muestra, la aparición o no de destete precoz de la lactancia materna, período de la lactancia materna exclusiva, si se ofreció dieta después del destete y las razones que llevaron a esta ocurrencia. Discusión y Conclusiones: La relación entre el destete precoz de la lactancia materna, con la consiguiente introducción de sustitutos de la leche materna, podría conllevar al desarrollo de diabetes mellitus tipo 1. (Rev Cuid 2012;3(3:293-9.Palabras clave: Diabetes Mellitus Tipo 1. Lactancia Materna. Enfermería. (Fuente: DeCS BIREME.

  5. Prevalencia de diabetes mellitus en perros mayores de 7 años con sobrepeso ICC>4

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    Galarza Molina, Emanuel Leonardo

    2016-01-01

    La presente investigación, se realizó en el cantón Cuenca, Provincia del Azuay, para determinar la prevalencia de diabetes mellitus (DM) en perros mayores a 7 años con sobrepeso y un ICC mayor a 4, se realizó en 10 clínicas veterinarias, en 250 perros, practicando un examen clínico, para verificar signos que asocien a la enfermedad (polidipsia, poliuria, polifagia y letargia), se obtuvo una gota de sangre del pabellón auricular, analizándose en el glucómetro para verificar los niveles de...

  6. Tratamiento con altas dosis de corticoides de Púrpura Trombocitopénica Inmune en paciente con Diabetes Mellitus y Obesidad Mórbida, un desafio metabólico

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    Juan Pedro Andreu Cuello; Juan Pablo Gatica Araneda; Patricio Alfaro-Toloza; Romina Olmos-de-Aguilera

    2012-01-01

    El manejo de la púrpura trombocitopénica inmune con altas dosis de corticoides en pacientes con diabetes mellitus y obesidad mórbida no está definido. Mujer de 64 años con obesidad mórbida, diabetes mellitus 2 y púrpura trombocitopénico inmune presenta trombocitopenia severa de 2 000 plaquetas asociada a equimosis extensas en ambas extremidades inferiores y glicemia descompensada. Se inició tratamiento con Metilprednisolona 500mg por tres días y luego Prednisona 60mg/día, al quinto día se aum...

  7. Complicaciones microvasculares en niños con diabetes mellitus tipo I

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    Machado1, Karina; Freire, María Victoria; Pérez, María del Luján; Montano4, Alicia

    2013-01-01

    Introducción: la diabetes mellitus (DM1) es la enfermedad crónica endocrinológica más frecuente en pediatría y de mayor repercusión sanitaria por la gravedad de sus complicaciones. Dentro de estas complicaciones tienen especial relevancia la afectación de la microvasculatura, que causa retinopatía, neuropatía y nefropatía. Estas complicaciones, si bien se manifiestan durante la edad adulta, comienzan a desarrollarse en la niñez. Existen normas internacionales para su identificación. Se citan ...

  8. Ejercicio de resistencia muscular en adultos con diabetes mellitus tipo 2 Exercício de resistência muscular em adultos com diabetes mellitus tipo 2 Endurance training in adults with diabetes mellitus type 2

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    Karina Asunción Muñoz Canché

    2005-02-01

    Full Text Available Objetivos. Probar la efectividad del ejercicio de resistencia muscular en las cifras de hemoglobina glucosilada (HbA1c, en la fuerza muscular y en la fortaleza muscular percibida; explorar la influencia de la dieta, otros ejercicios, hipoglucemiantes y manifestaciones asociadas a episodios de hipoglucemia o hiperglucemia sobre el control glucémico de adultos con diabetes mellitus tipo 2 provenientes de los consultorios de endocrinología de dos hospitales públicos de la Ciudad de Monterrey, México. Procedimientos básicos. Se usó un diseño de 12 semanas de grupo control no equivalente con dos grupos, experimental (n1 = 14 y control (n2 = 11. Los participantes contaron con la recomendación de su médico para participar. Las sesiones de ejercicio fueron de una hora, dos veces por semana. Resultados. El grupo experimental mostró decremento significativo en el porcentaje de HbA1c, e incremento en la fuerza muscular y fortaleza muscular percibida (p Objetivos: Provar a efetividade do exercício de resistência muscular nas taxas de hemoglobina A glicosilada (HbA1c, na força muscular e no fortalecimento muscular percebido, explorar a influência da dieta, outros exercícios, hipoglicemiantes e manifestações associadas a episódios de hipoglicemia ou hiperglicemia sobre o controle glicêmico de adultos com diabetes mellitus tipo 2, provenientes dos consultórios de endocrinologia de dois hospitales públicos da Cidade de Monterrey, México. Procedimentos básicos: Foi utilizado um desenho de 12 semanas de grupo controle não equivalente com dois grupos, experimental (n1=14 e controle (n2=11. Os participantes tiveram recomendação de seu médico para participar. As sessões de exercício foram de uma hora, duas vezes por semana. Resultados: O grupo experimental apresentou decréscimo significativo nas taxas de HbA1c, incremento na força muscular e fortalecimento muscular percebido (pObjectives. Test the effects of an endurance training

  9. Evaluación neurofisiológica y clínica en pacientes con diabetes mellitus

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    Roberto Portillo

    2005-03-01

    Full Text Available Objetivo: Determinar las características clínicas y hallazgos neurofisiológicos en pacientes diabéticos y correlacionar sus variables. Material y Métodos: Se evaluó 50 pacientes con diabetes mellitus del Hospital Nacional Guillermo Almenara. Se determinó edad, sexo, ocupación, tiempo de enfermedad, glicemia, dieta, tratamiento, sintomatología sensitiva, velocidad de conducción nerviosa motora y sensitiva de 12 nervios por paciente, 600 nervios en total, prevalencia de polineuropatía diabética (PND y relacionamos las variables con la PND. Resultados: El 90% de pacientes presentó compromiso, 86% con criterios de PND; la edad osciló entre 38 y 78 años (media=58,5 años, 36 fueron varones (72%, el tiempo de enfermedad promedio fue de 89 meses, la glicemia 143 mg/dL, 74% tenía dieta hipoglúcida, 48% refirió síntomas sensitivos. No hubo relación de PND con tiempo de enfermedad, glicemia, tratamiento o sintomatología sensitiva. Conclusiones: La exhaustiva anamnesis a pacientes diabéticos encontró 48% de sintomatología sugestiva de PND, 86% presentó hallazgos neurofisiológicos compatibles con PND, que no fue influida por otras variables; es imperativa la detección temprana de diabetes mellitus, para evitar complicaciones como la PND.

  10. Influencia de la diabetes mellitus sobre la evolución del paciente con enfermedad cerebrovascular y nutrición enteral por sonda

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    Coto García, Cristina

    2017-01-01

    La Diabetes Mellitus juega un importante papel tanto en la patogenia como en el pronóstico de la enfermedad cerebrovascular. El ictus y las complicaciones que este conlleva conforman una entidad de elevada morbimortalidad. El soporte nutricional constituye un pilar importante a la hora tratar a los pacientes que han sufrido un ictus. Valorar si existe diferencia en estancia media hospitalaria, éxitus y complicaciones relacionadas con la nutrición entre aquellos pacientes con diabetes melli...

  11. Caracterização de pessoas com Diabetes Mellitus Tipo 2 Caracterización de personas con Diabetes Mellitus Tipo 2 Characterization of people with Diabetes Mellitus Type 2

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    Maria de Fátima Ferreira Grillo

    2007-02-01

    Full Text Available O estudo teve por objetivo caracterizar pessoas com Diabete Melittus (DM Tipo 2, cadastrados em uma Unidade Básica de Saúde. É um estudo observacional, descritivo, do tipo série de casos, com uma amostra de 125 pessoas. Os resultados apresentaram, em sua maioria, pessoas do sexo feminino, na faixa etária dos 60 aos 69 anos e que recebiam de 1 a 2 salários mínimos por mês, hipertensos, dislipidêmicos, com sobrepeso e/ou obesidade, não praticando atividade física regularmente, com dificuldade em seguir a dieta e em conviver com a doença. Concluiu-se a importância de planejar Programas de Atenção à Saúde voltada para pessoas diabéticas, no contexto comunitário, com o incentivo da Educação em saúde por meio de uma equipe multidisciplinar.El estudio tiene por objetivo caracterizar personas con Diabetes Mellitus (DM Tipo 2, inscriptos en una Unidad Básica de Salud. Es un estudio de observación, descriptivo, de tipo serie de casos, con una muestra de 125 personas. Los resultados presentaron, en su mayoría, personas de sexo femenino, en la faja etaria de los 60 a los 69 años y que recibían de 1 a 2 sueldos mínimos por mes, hipertensos, dislipidémicos, con sobrepeso y/u obesidad, no practicando actividad física regularmente, con dificultades en seguir la dieta y en convivir con la enfermedad. Se concluye la importancia de planear Programas de Atención a la Salud volcada para personas diabéticas, en el contexto comunitario, con el incentivo de la Educación en salud por medio de un equipo multidisciplinar.This study has as its main objective the characterization of people with Diabetes Mellitus (DM Type 2 who were registered in a Basic Health Unit. It is an observational, descriptive study with a sample of 125 people. The results presented, in most part, female people, between their 60 and 69 years old who receive from 1 to 2 minimum salary per month, hypertensive, dyslipidemic, overweight and/or obese, people who do not

  12. Actividad física en pacientes ambulatorios con diabetes mellitus 2 de un Hospital Nacional del Perú

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    Ana Josefina Manzaneda

    Full Text Available Con el objetivo de determinar el nivel de actividad física que realizan los pacientes ambulatorios con diabetes mellitus tipo 2 (DM 2 que acuden a un Hospital Nacional de Lima, Perú se incluyó a 120 pacientes en quienes se aplicó el cuestionario internacional de actividad física IPAQ. El 66% fueron mujeres, la edad media fue 61,6 años, el 70% presentó mal control glicémico. El 20% de pacientes calificaba como inactivo, 68% con mínima actividad y 12% con actividad física adecuada. No se halló relación entre actividad física, tiempo de enfermedad, control glicémico, ni el índice de masa corporal. La edad se asoció negativamente con la actividad física. Se concluye que existen bajos niveles de actividad física en pacientes con DM 2 y esta no se enfoca en actividades de ocio que proveen beneficios a la salud

  13. Comportamiento del infarto agudo del miocardio en personas con diabetes mellitus de la provincia Granma Situation of the acute myocardial infarction in persons with diabetes mellitus in Granma province

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    Eduardo René Valdés Ramos

    2012-08-01

    Full Text Available Antecedentes: la diabetes mellitus, además de ser un factor de riesgo para el infarto agudo del miocardio, parece conferir per se un peor pronóstico en los pacientes con esta entidad. Objetivo: evaluar el comportamiento del infarto agudo del miocardio en personas con diabetes mellitus de la provincia de Granma. Métodos: se realizó un estudio transversal y descriptivo con 159 pacientes que ingresaron en la Unidad de Cuidados Intensivos Coronarios del Hospital "Carlos Manuel de Céspedes", de Bayamo, Granma, con diagnóstico de infarto agudo del miocardio, en el período comprendido entre enero de 2010 y junio de 2011. De ellos, 39 con diabetes mellitus y 120 sin ella. De las historias clínicas se extrajeron los datos de las variables demográficas, clínicas y metabólicas estudiadas. Resultados: en los casos con diabetes mellitus el porcentaje de infartos extensos y sin dolor precordial fue superior a los no diabéticos, sin llegar a ser estadísticamente significativo (p= 0,3283 y p= 0,1066. Los pacientes diabéticos presentaron 2,8 veces más posibilidad de sufrir una complicación eléctrica que aquellos sin diabetes mellitus (p= 0,0121. No hubo relación significativa entre las complicaciones mecánicas del infarto agudo del miocardio y la presencia de diabetes mellitus (p= 0,4104. El número de defunciones fue significativamente mayor en los casos con diabetes mellitus, que en los no diabéticos (p= 0,0124. Los niveles de glucemia al ingreso estuvieron significativamente más elevados en los casos complicados y fallecidos, tanto en los diabéticos como en los no diabéticos. Conclusiones: el infarto agudo del miocardio, en los pacientes diabéticos de nuestro medio, con frecuencia se presenta sin dolor precordial, extenso, con complicaciones eléctricas y asociado con una elevada mortalidad. La hiperglucemia al ingreso está relacionada con un incremento de la morbilidad y la mortalidad del infarto agudo del miocardio

  14. Conocimientos y conductas de los pacientes con diabetes mellitus sobre el pie diabético Knowledge and behaviors of the patients with diabetes mellitus in relation to the diabetic foot

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    Ulises de Jesús Gallardo Pérez

    2008-03-01

    Full Text Available Se identificaron los conocimientos y conductas de los pacientes con diabetes mellitus sobre el pie diabético. Se realizó un estudio cualitativo en 2 consultorios del Policlínico "Hermanos Ruíz Aboy", del municipio San Miguel del Padrón. Se ejecutaron 4 grupos focales, con un total de 28 participantes de ambos sexos, entre 50 y 80 años de edad. La mayoría de los pacientes mostró falta de conocimientos sobre la definición de pie diabético y sus factores de riesgo. Los pacientes realizan un autocuidado insuficiente de sus pies y asumen conductas de riesgo por la falta de educación. Consideramos importante reforzar el componente educativo en la atención integral de los pacientes con diabetes mellitus para elevar su nivel de conocimientos, crear hábitos saludables y evitar la aparición del pie diabético. La técnica del grupo focal constituyó un instrumento rápido y efectivo para la obtención de información.The knowledge and behavior of the patients with diabetes mellitus in connection with the diabetic foot were identified. A qualitative study was conducted in 2 family physician's offices of "Hermanos Ruíz Aboy" Polyclinic of San Miguel del Padrón municipality. 4 focal groups were selected with a total of 28 participants aged 50-80 of both sexes. Most of the patients lacked knowledge to define the diabetic foot and its risk factors. The patients' self-care of their feet is insufficient and they assume risk conducts due to their deficient education. It is important to reinforce the educative component in the comprehensive attention of the patients with diabetes mellitus to raise their knowledge level, to create healthy habits and to prevent the appearance of diabetic foot. The focal group technique is a rapid and effective tool to obtain information.

  15. Factores metabólicos asociados con la progresión hacia la diabetes mellitus en sujetos con tolerancia a la glucosa alterada Metabolic factors associated with the progression of diabetes mellitus in subjects with impaired glucose tolerance

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    Roberto M. González Suárez

    2007-12-01

    Full Text Available Se realizó un estudio prospectivo en 84 pacientes con tolerancia a la glucosa alterada (TGA, diagnosticada 18 años antes, para identificar factores metabólicos identificados en el estudio inicial, que pudieran estar asociados a la progresión hacia la diabetes mellitus (DM detectada en el estudio evolutivo. Como factores de riesgo metabólicos se consideraron la gravedad del trastorno de la tolerancia a la glucosa, la disminución o incremento de la secreción de insulina en ayunas y durante una PTG oral, así como la resistencia a la insulina detectada en ayunas o durante la PTG, todos ellos determinados con métodos y criterios de interpretación previamente establecidos y validados. Se encontró que la presencia de una baja respuesta insulínica inicial (II0-30 disminuido se asocia significativamente con la progresión hacia la diabetes en el grupo de sujetos con TGA estudiados. Este hallazgo es consistente en todos los aspectos del fenómeno evaluado (valores absolutos de las variables en los grupos de sujetos clasificados de acuerdo con su evolución, riesgo de evolución hacia la DM y tiempo hasta el diagnóstico de DM y está de acuerdo con el criterio de que el factor genéticamente determinado que condiciona el desarrollo de la DM es un defecto de la capacidad inicial de respuesta insulinosecretora a los cambios de la glicemia.A prospective study was conducted in 84 patients with impaired glucose tolerance (IGT diagnosed 18 years before to identify metabolic factors found in the initial study that could be associated with the progression to diabetes mellitus (DM detected in the evolutive study. The severity of the glucose tolerance disorder, the reduction or increase of insulin secretion on fasting or during an oral glucose tolerance test (OGTT, as well as the resistance to insulin detected on fasting or during the OGTT, were considered as risk factors. All of them were determined by methods and criteria of interpretation that were

  16. Síndrome DRESS inducido por fármacos antituberculosos en un paciente con diabetes mellitus tipo 2

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    Antonio Salas

    2012-04-01

    Full Text Available Presentamos el caso de un paciente varón de 48 años de edad, con diagnóstico de diabetes mellitus tipo 2, no controlada, de diez años de evolución, a quien se le diagnosticó tuberculosis pulmonar mediante signos clínicos, radiográficos y cultivo en esputo positivo para Mycobacterium tuberculosis, sensible a drogas antituberculosas de primera línea. Recibió isoniacida, rifampicina, etambutol y pirazinamida. Dos meses después de iniciado el tratamiento presentó hipersensibilidad a medicamentos, con los siguientes signos y síntomas: rash dérmico generalizado, prurito generalizado, anemia Coombs positiva, eosinofilia y síntomas sistémicos, compatibles con el síndrome DRESS (drug rash with eosinophilia and systemic symptoms. Ante ello, se suspendió la medicación antituberculosa y se instaló tratamiento con antihistamínicos y corticoides sistémicos, con remisión y mejoría de síntomas. Posteriormente, recibió un esquema individualizado de tratamiento para tuberculosis consistente en medicamentos mínimamente hemato-hepatotóxicos, similar al indicado en pacientes inmunosuprimidos. Desde entonces presenta baciloscopias negativas.

  17. Resultados de un seguimiento educativo a personas con diabetes mellitus tipo 2 y sobrepeso u obesidad Results of educational follow-up of persons with type 2 diabetes mellitus and overweight/obesity

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    Rosario García; Rolando Suárez

    2003-01-01

    El presente trabajo muestra los resultados de un seguimiento educativo a personas con diabetes mellitus tipo 2 y sobrepeso corporal u obesidad, realizado como continuidad del estudio latinoamericano PEDNID-LA, con el objetivo de evaluar, en forma prospectiva, los cambios clínicos, bioquímicos y terapéuticos obtenidos después de participar en un programa de educación grupal con metodología interactiva. El estudio incluyó 40 pacientes no insulino dependientes, obesos o en sobrepeso y preferente...

  18. ESTUDIO DEL PERFIL LIPÍDICO EN SUJETOS CON DIABETES MELLITUS TIPO 2 DE BOGOTÁ

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    M. Guerra

    2005-12-01

    Full Text Available Los diabéticos tipo 2 (DM 2 pobremente controlados (HbA1c = 7% exhiben disminución del estado antioxidante total y dislipidemia en comparación con los metabólicamente controlados, lo cual puede ser reflejo de incrementos de radicales libres de oxígeno, alteraciones del metabolismo de las lipoproteínas lo que contribuye a desarrollar fenómenos que conducen a complicaciones micro y macrovasculares. Se estudiaron 60 individuos (40-80 años no controlados (n=20, controlados (n=20 y sanos (n=20. El criterio del buen control de la diabetes fue % HbA1c < 7%. Mediante la prueba t de diferencia de medias suponiendo varianzas desiguales se compararon los grupos. Los niveles de Col T, LDL-C, VLDL-C, TG y apo B-100 fueron significativamente más altos (p<0.05 y los de HDL-C y apo A-I más bajos en los DM 2 no controlados comparados con los niveles de los grupos de sujetos con DM 2 controlados y los controles sanos. Los pacientes con regular o pobre control glicémico presentan un perfíl lipídico anormal. Estos resultados son similares al de otros investigadores de diversas latitudes.

  19. Apego al tratamiento farmacológico en pacientes con diagnóstico de diabetes mellitus tipo 2

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    Durán-Varela Blanca Rosa

    2001-01-01

    Full Text Available Objetivos. Establecer la frecuencia de apego al tratamiento farmacológico en pacientes diabéticos tipo 2, relacionarla con el control metabólico e identificar factores que influyen para el no apego. Material y métodos. Estudio transversal comparativo, efectuado en 150 pacientes con diabetes mellitus tipo 2 de la unidad de medicina familiar No. 33 del Instituto Mexicano del Seguro Social de Chihuahua, Chih., México, hecho entre 1997 y 1998. Se midió el apego con cuenta de tabletas en su domicilio. El control metabólico se midió con hemoglobina glucosilada. Un cuestionario investigó factores relacionados. Se utilizó estadística descriptiva, t de Student y razón de momios. Resultados. El apego correspondió a 54.2%. Los factores asociados al no apego fueron la escolaridad primaria y la falta de información sobre la enfermedad (phttp://www.insp.mx/salud/index.html

  20. Representações sociais do pé diabético para pessoas com diabetes mellitus tipo 2 Representaciones sociales del pie diabético para personas con diabetes mellitus tipo 2 Social representations of diabetic foot for people with type 2 diabetes Mellitus

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    Maria Seloi Coelho

    2009-03-01

    Full Text Available Trata-se de uma pesquisa qualitativa que objetivou compreender as representações sociais do pé diabético para pessoas com diabetes mellitus tipo 2. Foram realizadas entrevistas semi-estruturadas, com dez pessoas com diabetes mellitus que participavam de um grupo de convivência. Da análise de conteúdo emergiram duas categorias: a doença do pé com alterações percebidas e ameaças presentes e; o cuidado com os pés, com o cuidado como preocupação com o futuro e não cuidado como sentimento de culpa. Os resultados mostraram que movidos pelas representações de alterações e ameaças os sujeitos buscam no cuidado uma esperança de não desenvolver a doença do pé ou controlar a situação. Quando o não-cuidado ocorre, surge o sentimento de culpa por terem conhecimentos e não se cuidarem. As representações sociais contribuíram na busca da compreensão do modo como os sujeitos com diabetes mellitus constroem saberes que expressam sua identidade e guiam seus comportamentos, especialmente vinculado ao pé diabético.Se trata de una investigación cualitativa que tuvo como objetivo comprender las representaciones sociales de pies diabético para personas con diabetes mellitus tipo 2. Fueron realizadas entrevistas semi-estructuradas, con diez personas con diabetes mellitus que participaban de un grupo de convivencia. Del análisis de contenido emergieron dos categorías: la enfermedad del pie con alteraciones percibidas y amenazas presentes y; el cuidado con los pies, con el cuidado como preocupación con el futuro y no cuidado como sentimiento de culpa. Los resultados mostraron que movidos por las representaciones de alteraciones y amenazas los sujetos buscan en el cuidado una esperanza de no desarrollar la enfermedad del pie o de controlar la situación. Cuando ocurre el no cuidado surge el sentimiento de culpa por tener los conocimientos y no utilizarlos. Las representaciones sociales contribuyeron en la búsqueda de la comprensi

  1. Capacidade funcional dos pacientes com diabetes mellitus e pé ulcerado Capacidad funcional de pacientes con diabetes mellitus y pié ulcerado Functional capability of patients with diabetes with foot ulceration

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    Geraldo Magela Salomé

    2009-01-01

    Full Text Available OBJETIVO: Avaliar a capacidade funcional de pessoas com diabetes mellitus e pé ulcerado. MÉTODOS: Estudo analítico, transversal e comparativo, realizado em hospital público do município de São Paulo, sendo os dados coletados no período de 2 de junho a 30 julho de 2008. Foram selecionados para compor o Grupo de Estudo, 20 pacientes com diabetes mellitus e pé ulcerado; para o Grupo Controle 20 pessoas com diagnóstico médico de diabetes mellitus, sem úlcera no pé. O instrumento utilizado foi Health Assessment Questionnaire-20. RESULTADOS: O grupo estudo diferiu do grupo controle, quanto ao escores HAQ-20, bem como em relação aos componentes 1,2,3,5,6,7 e 8. Também apresentaram diferença estatística significante (POBJETIVO: Evaluar la capacidad funcional de personas con diabetes mellitus y pié ulcerado. MÉTODOS: Se trata de un estudio analítico, transversal y comparativo, realizado en un hospital público del municipio de Sao Paulo, cuyos datos fueron recolectados en el período del 2 de junio al 30 julio del 2008. Fueron seleccionados para componer el Grupo de Estudio, 20 pacientes con diabetes mellitus y pié ulcerado; para el Grupo Control 20 personas con diagnóstico médico de diabetes mellitus, sin úlcera en el pié. El instrumento utilizado fue el Health Assessment Questionnaire-20. RESULTADOS: El grupo de estudio difirió del grupo control, en cuanto a los escores HAQ-20, así como en relación a los componentes 1,2,3,5,6,7 y 8. También presentaron diferencia estadísticamente significativa (POBJECTIVE: To evaluate and compare the functional capability of patients with diabetes with foot ulceration and patients with diabetes without foot ulceration. METHODS: A cross sectional descriptive comparative study was conducted in a public hospital in the district of São Paulo. The sample consisted of 20 patients with foot ulceration and 20 patients without foot ulceration. Data were collected from June 2 to July 30, 2008. The

  2. Hallazgos electroencefalográficos e hipoglucemia severa en niños con diabetes mellitus tipo 1 Electroencephalographic findings and severe hypoglycemia in children with type 1 diabetes mellitus

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    Pedro González Fernández

    2003-08-01

    Full Text Available Los episodios de hipoglucemia severa (HS constituyen un riesgo por ocasionar alteraciones de la función cerebral y del trazado electroencefalográfico (EEG en pacientes con diabetes. El presente estudio tiene como objetivo determinar la frecuencia de alteraciones del EEG después del diagnóstico de diabetes en un grupo de niños y su posible relación con HS, edad, control metabólico y tiempo de evolución de la diabetes. Se estudiaron retrospectivamente 40 niños con edades comprendidas entre 1 y 17 años (media de 12 años con diagnóstico de diabetes mellitus tipo 1 atendidos en el servicio de endocrinología del Hospital Pediátrico Docente "William Soler", en el período comprendido entre abril de 1990 y abril de 1998. Se tomaron los resultados de la hemoglobina glucosilada, así como los episodios referidos de HS. Se realizó EEG al diagnóstico de la diabetes y anualmente. Se clasificaron los EEG anormales de acuerdo con el tipo de trazado. Se encontraron EEG anormales en aproximadamente la mitad de los pacientes (45 % con predominio del trazado con descargas focales, los que fueron significativamente mayor en los pacientes con 2 ó más HS y con una edad menor al diagnóstico de la diabetes. No se encontró relación entre el EEG anormal y el control metabólico ni con el tiempo de evolución de la diabetes. La frecuencia hallada en este estudio enfatiza la importancia de realizar EEG al diagnóstico de DM y posteriormente, sobre todo en aquellos pacientes con HS y edad menor de 6 años.Episodes of severe hypoglycemia (SH constitute a risk because it causes brain function and electroencephalographic recording (EEG disturbances in patients with diabetes. This study was aimed at determining the frequency of EEG alterations after the diagnosis of diabetes in a group of children and their possible relation with SH, age, metabolic control and progression of diabetes. Forty children aged 1 to 17 years (average 12 years diagnosed with type 1

  3. Uveitis and diabetes mellitus

    NARCIS (Netherlands)

    Rothova, A.; Meenken, C.; Michels, R. P.; Kijlstra, A.

    1988-01-01

    Of 340 patients with anterior uveitis, 20 (6%) had diabetes mellitus. This is significantly higher than the prevalence of 1.4% in the normal Dutch population (P less than .001). Of 128 patients with idiopathic anterior uveitis, 16 (12.5%) had diabetes mellitus compared to only four (1.9%) of 212

  4. Risk factors in patients with type 2 diabetes mellitus Factores de riesgo en pacientes con diabetes mellitus tipo 2 Fatores de risco em pacientes com diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Idalina Diair Regla Carolino

    2008-04-01

    Full Text Available This study was carried out to evaluate the risk factors of type 2 diabetic patients through sociodemographic data, habits of health, anthropometric and biochemist profiles, assisted at a basic public health care unit in Maringá, Paraná. Sixty-six patients, 56 women aged over than 50 years-old were interviewed. High prevalence factors for cardiovascular risk were observed, such as: overweight and obesity, hypertension, dyslipidemia, sedentariness and inadequate diet. Data suggested the need for multidisciplinary intervention programs in health care units associated to educative programs, adjusted diet intake and regular physical activity for these diabetic patients.El objetivo de este estudio fue verificar los factores de riesgo de las complicaciones de la diabetes mellitus tipo 2, por medio del levantamiento de datos sociodemográficos, hábitos de salud, perfil antropométrico y bioquímico, de pacientes diabéticos tipo 2 atendidos en una Unidad Básica de Salud en la ciudad de Maringá, Paraná. Fueron entrevistados y evaluados 66 pacientes con más de 50 años; 56 eran del sexo femenino. Se verificó una elevada presencia de factores de riesgo cardiovascular en los pacientes investigados: sobrepeso y obesidad, hipertensión, dislipidemia, sedentarismo y dieta no saludable. Los resultados indican la necesidad de la implantación de programas de intervención multidisciplinares en unidades básicas de la salud asociada a prácticas educativas, estimulando la adopción de una dieta saludable y la práctica de actividad física regular para estos pacientes.O objetivo deste estudo foi verificar os fatores de risco das complicações do diabetes mellitus tipo 2, por meio de levantamento de dados sociodemográficos, hábitos de saúde, perfil antropométrico e bioquímico de pacientes diabéticos tipo 2, atendidos em Unidade Básica de Saúde, na cidade de Maringá, Paraná. Foram entrevistados e avaliados 66 pacientes acima de 50 anos, sendo 56

  5. Maduración sexual en niños con diabetes mellitus tipo 1 tratados con dosis múltiples de insulina Sexual maturation in children presenting with Type 1 diabetes mellitus treated with multiple dose of insulin.

    Directory of Open Access Journals (Sweden)

    Tania Espinosa Reyes

    2007-04-01

    Full Text Available Antes de la terapia insulínica, la menarquia y menstruaciones subsecuentes aparecían raramente en niñas con diabetes mellitus tipo 1 (DM 1 desde la infancia, y en los varones se verificaba un importante retraso puberal. El objetivo del presente trabajo es evaluar el inicio de la pubertad, y la influencia de la edad de diagnóstico de la diabetes y el grado de control metabólico, sobre el desarrollo sexual en un grupo de ninos atendidos en consultas de endocrinología pediátrica. Se realizó un estudio prospectivo no concurrente a partir de las historias clínicas de pacientes tratados con dosis múltiples de insulina, de procedencia urbana (32 varones y 28 hembras, seguidos longitudinalmente por examen clínico y determinaciones bioquímicas periódicas desde el inicio de la DM 1 hasta alcanzar su talla final. El control metabólico fue evaluado a través de la hemoglobina glicosilada (HbA1 realizada trimestralmente, y clasificado según criterios de la institución en bueno (B: 10 %. La media de la edad a la que se encontró un volumen testicular de 4 mL fue 12,5 ± 0,8 años; en las niñas el inicio del desarrollo mamario se constató a la edad promedio de 11,4 ± 1,3 años y la menarquia ocurrió a los 12,9 ± 1,2 años. Se comprobó también que 31 pacientes tuvieron un control metabólico B (51,6 %, 22 R (36,7 % y 7 M (11,7 %. Se concluye que el tratamiento con dosis múltiples de insulina tiene una influencia favorable y decisiva sobre el grado de control metabólico, lo cual hace posible un desarrollo puberal adecuado en pacientes con DM 1.Before insulin therapy, menarche and subsequent menstruation rarely appear in girls presenting Type 1 diabetes mellitus (MD 1 from childhood, and in boys a significicant pubertal retardation was confirmed. Aim of present paper is to assess onset of puberty, influence of diagnosis age of diabetes, and degree of metabolic control, on sexual development in a cohort of children seen in service of

  6. Prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2

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    Dulman O. Pineda-De Paz

    2018-03-01

    Full Text Available Resumen: Introducción: La enfermedad cardiovascular es la causa principal de muerte en pacientes con diabetes mellitus. La prevalencia de cardiopatía isquémica asintomática es más alta en pacientes diabéticos que en no diabéticos y se asocia a peor pronóstico. Objetivo: Identificar la prevalencia de cardiopatía isquémica asintomática en pacientes con diabetes mellitus tipo 2 en un hospital de tercer nivel de atención de Guatemala y analizar la posible asociación de dicha enfermedad con características epidemiológicas, clínicas y metabólicas. Métodos: Estudio de corte transversal en el que se estudió una muestra de 92 pacientes diabéticos seleccionados de forma aleatoria simple. Se realizó electrocardiograma, que cuando fue negativo para isquemia ameritó prueba de esfuerzo, o de lo contrario, ecocardiograma de estrés con dobutamina. Resultados: La edad media de los participantes fue de 57 años, 88% de los cuales eran mujeres; la duración media de la diabetes fue 7 años. Se encontró cardiopatía isquémica asintomática en el 22,8% de los casos. No se hallaron posibles asociaciones entre cardiopatía isquémica asintomática y edad, sexo, enfermedad arterial periférica, índice de masa corporal, índice tobillo-brazo, hipertensión arterial, dislipidemia, tabaquismo activo, sedentarismo, sobrepeso/obesidad, alcoholismo, glucosa en ayunas, hemoglobina glicosilada, colesterol total, colesterol HDL, colesterol LDL, ácido úrico, creatinina, tasa de filtrado glomerular y microalbuminuria. Conclusiones: La prevalencia de cardiopatía isquémica asintomática en la población estudiada con diabetes mellitus tipo 2 fue de 22,8%. No se encontraron posibles asociaciones de cardiopatía isquémica asintomática con las variables estudiadas. Abstract: Introduction: Cardiovascular disease is the main cause of death in patients with diabetes mellitus. The prevalence of asymptomatic ischaemic heart disease is higher in diabetic

  7. Diabetes Mellitus and Hypertension

    OpenAIRE

    Tuğrul, Armağan

    2014-01-01

    Hypertension is a major worldwide health problem. Its prevalence is 1.5-2 times higher in diabetic population than that in non-diabetic individuals. Its pathogenesis depends on diabetic nephropathy in type 1, whereas may be multifactorial in type 2 diabetes mellitus. In diabetics, angiotensin converting enzyme inhibitors are most widely preferred in the treatment of hypertension because of their numerous desirable effects. In this article, the most recent data are presented on the relationshi...

  8. Adherencia al tratamiento nutricional en pacientes con diabetes mellitus tipo 2 que asisten a un programa educativo

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    Mariela A. Carvajal

    2017-03-01

    Full Text Available El objetivo de este estudió fue evaluar la adherencia al tratamiento nutricional por medio de la hemoglobina glicosilada en pacientes con diabetes mellitus tipo 2 que asistieron a un programa educativo en diabetes en la ciudad de Guatemala, así como evaluar los principales factores que influyen en ella. Se realizó un estudio de tipo prospectivo, longitudinal, experimental, pareado de intervención no medicamentosa. Se utilizó la prueba de Morinsky-Green Levine para evaluar la adherencia al tratamiento nutricional, el cual consiste en cuatro preguntas de auto informe sobre la adherencia. La muestra estuvo conformada por 126 pacientes que recibieron una intervención educativa durante cinco meses. La metodología utilizada permitió analizar la adherencia al tratamiento por medio de la prueba de hemoglobina glicosilada, una encuesta de adherencia, evaluación del consumo por grupos de alimentos al inicio y al final. Uno de los principales hallazgos fue que los pacientes están convencidos que su plan nutricional les beneficia y les evitaría complicaciones. El apoyo familiar también juega un papel muy importante en la adherencia de estos pacientes al tratamiento nutricional. Los indicadores de adherencia que se encontraron más afectados son los relacionados al costo del plan de alimentación y la dificultad para seguirlo. Se concluye que es posible utilizar la hemoglobina glicosilada como un indicador efectivo de adherencia, ya que el porcentaje de pacientes con hemoglobina glicosilada controlada aumentó de un 50 a un 65.9% después de la intervención.

  9. Asociación entre el déficit de vitamina D y bienestar emocional en pacientes con Diabetes Mellitus tipo 1

    OpenAIRE

    Waselle Vallina, Rebeca

    2016-01-01

    Introducción: La deficiencia de vitamina D se asocia con un mayor riesgo de padecer enfermedades autoinmunes, como sería el caso de los pacientes con diabetes mellitus tipo 1. Esta enfermedad tiene un impacto, sobre la calidad de vida y el bienestar emocional de los pacientes, relacionado con el control glucémico, las complicaciones y algunas variables socioeconómicas. Objetivos: El objetivo principal fue evaluar el grado de asociación entre la vitamina D y el bienestar emocional de los ...

  10. RENOPROTECTION IN DIABETES MELLITUS

    African Journals Online (AJOL)

    diabetes mellitus (DM) (Table I).1 In response to the increasing threat ... formation of reactive oxygen species (ROS); generation of advanced glycation ... There is sufficient evidence that certain therapies protect the kidneys from the long-term ...

  11. Apego al tratamiento farmacológico en pacientes con diagnóstico de diabetes mellitus tipo 2 Pharmacological therapy compliance in diabetes

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    Blanca Rosa Durán-Varela

    2001-06-01

    Full Text Available Objetivos. Establecer la frecuencia de apego al tratamiento farmacológico en pacientes diabéticos tipo 2, relacionarla con el control metabólico e identificar factores que influyen para el no apego. Material y métodos. Estudio transversal comparativo, efectuado en 150 pacientes con diabetes mellitus tipo 2 de la unidad de medicina familiar No. 33 del Instituto Mexicano del Seguro Social de Chihuahua, Chih., México, hecho entre 1997 y 1998. Se midió el apego con cuenta de tabletas en su domicilio. El control metabólico se midió con hemoglobina glucosilada. Un cuestionario investigó factores relacionados. Se utilizó estadística descriptiva, t de Student y razón de momios. Resultados. El apego correspondió a 54.2%. Los factores asociados al no apego fueron la escolaridad primaria y la falta de información sobre la enfermedad (phttp://www.insp.mx/salud/index.htmlObjective. To establish the frequency of compliance to pharmacological therapy, and to identify non-compliance factors, in relation to metabolic control on patients with type-II diabetes mellitus. Material and methods. A comparative cross-sectional study was conducted between 1997 and 1998, among 150 type-II diabetic patients, at the Family Medicine Unit No. 33, of the Mexican Institute of Social Security, in Chihuahua, Mexico. Compliance to drug therapy was measured by counting tablets at home. Metabolic control was measured through glycosilated hemoglobin. A questionnaire was given to collect data on factors related to compliance. Statistical analysis consisted of descriptive statistics, Student's t and odds ratios. Results. Pharmacological therapy compliance was 54.2%. Factors associated with non-compliance were elementary schooling and lack of information about the disease. Conclusions. Pharmacological therapy compliance was low. Factors related to non-compliance can be modified through education. The English version of this paper is available at: http://www.insp.mx/salud/index.html

  12. Factors associated with therapy noncompliance in type-2 diabetes patients Frecuencia y factores asociados al incumplimiento terapéutico en pacientes con diabetes mellitus tipo 2

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    Lizbeth Hernández-Ronquillo

    2003-06-01

    Full Text Available OBJECTIVE: To identify the frequency and factors associated with therapy noncompliance in type-2 diabetes mellitus patients. MATERIAL AND METHODS: A cross-sectional study was carried out in 79 patients with type-2 diabetes mellitus seen in major hospitals of Mexico City. Patients were visited at home, from March 1998 to August 1999, to measure compliance with prescribed therapy. Complying patients were defined as those taking at least 80% of their pills or 80% of their corresponding insulin dose. The degree of compliance with therapy components (diet, amount of exercise, and keeping appointments was measured. RESULTS: The average age of study subjects was 59 years (SD 11 years; 73% (n=58 were female subjects. The overall frequency of noncompliance was 39%. Noncompliance rates were: 62% for dietary recommendations, 85% for exercise, 17% for intake of oral hypoglycemic medication, 13% for insulin application, and 3% for appointment keeping. Hypertension plus obesity was the only factor significantly associated with noncompliance (OR 4.58, CI 95% 1.0, 22.4, p=0.02. CONCLUSIONS: The frequency of therapy noncompliance was very high, especially for diet and exercise.OBJETIVO: Identificar la frecuencia y factores asociados al incumplimiento terapéutico en pacientes con diabetes mellitus tipo 2. MATERIAL Y MÉTODOS: Se llevó a cabo un estudio transversal en cuatro clínicas y hospitales de la Ciudad de México, en 79 pacientes con diabetes mellitus tipo 2. Se recolectaron datos sobre el cumplimiento terapéutico, para lo cual se visitó el domicilio de los sujetos de estudio entre marzo de 1998 y agosto de 1999, con el fin de contar los medicamentos. Se definió cumplimiento cuando el paciente administró correctamente 80% de las pastillas o de la dosis de insulina que le correspondía. Se midió el grado de cumplimiento para cada una de las medidas terapéuticas (dieta, ejercicio y asistencia a citas. RESULTADOS: La edad promedio del grupo fue de 59

  13. Celulitis orbitaria bilateral con endoftalmitis en una paciente con reciente diagnóstico de diabetes mellitus tipo 2

    OpenAIRE

    Farrell González, Lesley; Ezpeleta Rodríguez, Mayra M.; Sierra Garcia, Carlos; Mayer Rivera, Francisco

    2014-01-01

    Se presentó una mujer de 74 años al servicio de urgencias del HRAEBI, ISSSTE, el día 2 de septiembre de 2010 con datos de desequilibrio hidroelectrolítico, hipotensión y conjuntivitis bilateral. Sus signos vitales durante su estancia en urgencias fueron: tensión arterial, 80/40 mmHg; temperatura, 38.5 °C; frecuencia respiratoria, 22 rpm; frecuencia cardíaca 89 lpm Se interconsulta al servicio de Oftalmología quienes diagnosticaron celulitis orbitaria bilateral, con no percepción de luz en amb...

  14. Asociación entre diabetes mellitus tipo 2 y actividad física en personas con antecedentes familiares de diabetes

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    Fanny Petermann

    2018-05-01

    Full Text Available Resumen: Objetivo: Investigar si la asociación entre diabetes mellitus tipo 2 (DMT2 y antecedentes familiares de DMT2 resulta modificada por los niveles de actividad física en población chilena. Método: Se incluyeron en el estudio 5129 participantes de la Encuesta Nacional de Salud de Chile. El tiempo destinado a realizar actividad física se determinó por el cuestionario GPAQ v2, y los antecedentes familiares mediante el autorreporte de cada participante. La asociación entre DMT2, antecedentes familiares de DMT2 y actividad física fue investigada por sexo mediante regresión logística. Resultados: El riesgo de desarrollar DMT2 en personas con antecedentes familiares de esta enfermedad es elevado, independientemente de su nivel de actividad física y de su adiposidad. Tanto las mujeres como los hombres físicamente inactivos y con antecedentes familiares de DMT2 presentan mayor probabilidad de desarrollar DMT2 (odds ratio [OR] mujeres: 5,49; intervalo de confianza del 95% [IC95%]: 3,85-7,84; p <0,0001; y OR hombres: 8,16; IC95%: 4,96-13,4; p <0,0001, comparados con sus pares sin antecedentes familiares y activos físicamente. Conclusión: Dado el alto riesgo de desarrollar DMT2 que presentan los individuos con antecedentes familiares de esta enfermedad, y el efecto de la actividad física en la disminución de dicho riesgo, es esencial incrementar los niveles de actividad física en la población que presenta mayor susceptibilidad a DMT2. Abstract: Objective: To investigate whether the association between type 2 diabetes (T2D and family history of diabetes is modified by the levels of physical activity in the Chilean population. Method: In this study were included 5129 participants from the cross-sectional 2009-2010 National Health Survey. Physical activity level was assessed using the Global Physical Activity Questionnaire and family history of T2D, through self-reporting. The association between diabetes, family history of diabetes and

  15. Efectividad de la educación diabetológica sistematizada en niños que debutan con Diabetes Mellitus tipo 1 Effectiveness of systematic diabetes education in children diagnosed with Diabetes Mellitus type 1 (DM1

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    Manuel Montilla-Pérez

    2012-06-01

    Full Text Available Objetivo principal: Evaluar la efectividad de la educación diabetológica sistematizada en niños que debutan con DM1 en el Hospital Universitario de Fuenlabrada (HUF, Madrid. Metodología: Estudio comparativo entre dos muestras de niños de 0 a 14 años que debutaron con DM1 antes y después de haberse instaurado un programa de educación diabetológica Se estudió a 34 niños adscritos al HUF que ingresaron por debut de DM1. Para evaluar la efectividad del programa se realizaron análisis bivariados con el fin de encontrar relaciones entre la educación diabetológica sistematizada y las variables: días de ingreso, frecuentación a urgencias por complicaciones, permisos domiciliarios y HbA1c a los 3 y 6 meses del alta. Resultados principales: Los días de ingreso se redujeron 3 días (pObjective: Evaluate the effectiveness of systematic diabetes education in children diagnosed with Diabetes Mellitus type 1 (DM1, in Fuenlabrada University Hospital (Madrid. Methods: A comparative study of two sample groups of children aged 0 to 14 diagnosed with DM1, before and after having been inducted into the diabetes education program. 34 children, admitted with a DM1 diagnosis, both with and without ketoacidosis, and assigned to Fuenlabrada University Hospital were studied. To evaluate the effectiveness of the program, bivariable analysis was undertaken with the objective of finding relationships between systematic diabetes education and the variables. Those variables were; admission days, frequency of visits to the emergency ward due to complications, and permissions to go home and HbA1c at 3 to 6 months after discharge from the hospital. Results: The admission days was reduced 3 days (p< 0.001, the complications within the 6 month after discharge decreased 41,2% and the permissions to go home increased 23,6% (p=0.001. Conclusions: The results of the study suggest the effectiveness of systematic diabetes education.

  16. La diabetes mellitus y las complicaciones cardiovasculares

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    Olga Lidia Pereira Despaigne

    2015-05-01

    Full Text Available Las enfermedades cardiovasculares en las personas con diabetes mellitus son más precoces, y suelen presentarse con síntomas y signos atípicos. Igualmente, se ha demostrado que la hiperglucemia es un importante factor de riesgo para las complicaciones microangiopáticas y macroangiopáticas en la diabetes mellitus, y la hiperglucemia posprandial, con glucemia en ayunas normal, es una condición clínica frecuente y un factor de riesgo cardiovascular independiente. Así, en el presente trabajo se exponen algunas consideraciones relacionadas con el control de las dislipidemias, la hipertensión arterial y la antiagregación plaquetaria en el paciente con diabetes mellitus

  17. AUTOCUIDADO DE LAS ADULTAS MAYORES CON DIABETES MELLITUS INSCRITAS EN EL PROGRAMA DE ENFERMEDADES CRÓNICAS EN TEMOAYA, MÉXICO

    OpenAIRE

    Méndez Salazar,Vianey; Becerril Estrada,Verónica; Morales del Pilar,Matiana; Pérez Ilagor,Víctor Manuel

    2010-01-01

    Los sujetos de estudio fueron un total de diez adultas mayores con un promedio de 63 años, en la unidad de Salud de San Pedro Arriba, Municipio de Temoaya. La unidad de salud constituye un escenario para la capacitación del usuario, sin embargo se presentan condicionantes en las adultas mayores para no aplicar lo aprendido. El objetivo de la investigación fue el describir las actividades de autocuidado en el adulto mayor con diabetes mellitus tipo 2, inscritos al programa de enfermedades crón...

  18. Intervención educativa en adultos mayores con diabetes mellitus en Guatemala

    OpenAIRE

    José Manuel Contreras Tejeda; Arely Díaz Cifuentes; Mayda Díaz Pérez; Aurora Seara Cifuentes

    2014-01-01

    Se realizó un estudio de intervención comunitaria, con el objetivo de incrementar los conocimientos en pacientes diabéticos adultos mayores, pertenecientes al Departamento Alta Verapaz, Cobán, Guatemala; en el período comprendido desde junio de 2011 hasta junio de 2012. El universo de estudio estuvo constituido por los pacientes diabéticos dispensarizados por el médico y la enfermera en el área periférica, conformándose la muestra con 46 de ellos, a los cuales se les evaluó el grado de conoci...

  19. Control glucémico en el proceso perioperatorio de los pacientes con diabetes mellitus Glycemia control in the perioperative process of patients presenting with diabetes mellitus

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    Yudit García García

    2012-04-01

    Full Text Available El paciente diabético requiere con frecuencia algún tipo de cirugía o la realización de un proceder diagnóstico invasivo, que puede, incluso, ser realizado de urgencia. En la actualidad el riesgo quirúrgico del diabético ha disminuido gracias a los avances en las técnicas anestésicas y al control metabólico perioperatorio, aunque las complicaciones aún son más frecuentes, y generan una hospitalización prolongada y una tasa mayor de invalidez. En la evaluación preoperatoria se deben precisar las características de la diabetes, el tipo de proceder quirúrgico, el riesgo anestésico quirúrgico, y realizar los ajustes necesarios al tratamiento habitual. La infusión continua de insulina endovenosa con aporte de glucosa es el método más racional y fisiológico en la mayoría de las intervenciones quirúrgicas, lo que implica monitoreo glucémico frecuente con ajustes inmediatos. Algunas situaciones especiales, como las cirugías complejas o las de urgencia, requieren esquemas terapéuticos específicos, por lo que cada equipo debe tener su protocolo de trabajo, según las particularidades de las intervenciones quirúrgicas que realicen. El control metabólico perioperatorio es esencial para evitar las alteraciones metabólicas e hidroelectrolíticas agudas y favorecer la evolución satisfactoria en el posoperatorio. Por su importancia, se realiza una revisión con un enfoque actual, que ayude a mejorar la calidad de la atención al paciente diabético que requiere de una intervención quirúrgica.The diabetic patients require frequently some type of surgery or the implementation of an invasive diagnostic procedure which may even be carried out as an emergence. Nowadays the surgical risk of the diabetic patient has decrease thanks to the advances in the anesthetic techniques and to the perioperative metabolic control, although the complications are more frequent and to generate a lengthy hospitalization and a great disability rate

  20. Factores predictivos de la microalbuminuria en pacientes pediátricos con diabetes mellitus tipo 1 (DMt1

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    Paola Marianella Pinto Ibárcena

    2012-10-01

    Full Text Available La nefropatía constituye la complicación más grave de la diabetes mellitus tipo 1 (DMt1 siendo una de las manifestaciones iniciales la microalbuminuria. Objetivos: Determinar el comportamiento de los factores epidemiológicos, clínicos y bioquímicos en el desarrollo de microalbuminuria en pacientes con DMt1. Diseño: Estudio de casos y controles. Lugar: Servicio de Endocrinología del Instituto Nacional de Salud del Niño, Lima, Perú. Participantes: Pacientes diabéticos tipo 1 menores de 18 años. Intervenciones: Se estudió 64 pacientes portadores de DMt1, 22 con microalbuminuria y 42 sin esta manifestación, que constituyeron los casos y controles respectivamente. Se consignó como factores epidemiológicos la edad al diagnóstico, tiempo de evolución, género, antecedentes familiares de diabetes, nefropatía, dislipidemia, hipertensión arterial; como factores clínicos, el estado nutricional, desarrollo puberal (Tanner, presión arterial; y como factores bioquímicos, la hemoglobina glicosilada (HbA1c, microalbuminuria y perfil lipídico. Tanto los casos como los controles fueron seguidos durante un año. El análisis estadístico se hizo mediante pruebas de chi cuadrado, odds ratio y regresión logística, para establecer predominancia de factores. Principales medidas de resultados: Estadio puberal, perfil lipídico y HbA1c. Resultados: Los factores de riesgo hallados fueron la presión arterial diastólica elevada (p=0,037, la pubertad (p=0,008, HbA1c alta (p< 0,0001, hipertrigliceridemia (p= 0,007 y la hipercolesterolemia (p< 0,0001. Conclusiones: La HbA1c elevada, la hipercolesterolemia y la pubertad fueron los factores de riesgo de mayor preponderancia para el desarrollo de microalbuminuria. A fin de prevenir el desarrollo de microalbuminuria, se sugiere buen control metabólico y cuidadoso manejo de la dislipidemia, en especial en pacientes púberes.

  1. Adaptación cultural al español y validación psicométrica del Summary of Diabetes Self-Care Activities measure (SDSCA en personas con diabetes mellitus tipo 2

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    Jorge Caro-Bautista

    2016-08-01

    Conclusiones: El SDSCA-Sp en una versión válida en la práctica clínica y en investigación para evaluar autocuidados en diabetes mellitus tipo 2 con propiedades clinimétricas similares a las obtenidas en estudios previos.

  2. Caracterización del control metabólico en niños y adolescentes con diabetes mellitus tipo 1 Characterization of the metabolic control in children and adolescents with type I diabetes mellitus

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    Pedro González Fernández

    2012-08-01

    Full Text Available Introducción: el control metabólico es el propósito principal en el tratamiento de la diabetes mellitus. Objetivo: caracterizar el control metabólico en un grupo de niños y adolescentes con diabetes mellitus tipo 1. Métodos: se realizó un estudio prospectivo en 84 pacientes con diabetes mellitus tipo 1 atendidos en el servicio de Endocrinología del Hospital Pediátrico Universitario "William Soler" entre febrero de 2010 y agosto de 2011. Se determinó hemoglobina glucosilada (HbA1c con un intervalo de entre 90 y 120 días. Para la determinación de la HbA1c se utilizó el método cuantitativo turbidimétrico con el reactivo fabricado por Futura System. Los resultados trimestrales de HbA1c se relacionaron con la edad, el sexo, el tiempo de evolución de la diabetes mellitus, el peso corporal en kilogramos y la dosis total diaria de insulina. Resultados: la edad promedio de los pacientes del sexo masculino fue 11,6 años (DS 4,6 y la de los del sexo femenino, 12,4 años (DS 4,5. La edad media al inicio del estudio fue 12,23 años (DS 4,42 y la edad media al diagnóstico de la diabetes, 8,27 años (DS 4,28. El tiempo promedio de evolución de la diabetes fue 3,79 años (DS 3,17 y la dosis media diaria de insulina por kilogramo de peso corporal fue de 0,91 unidades (DS 0,26. Los valores de la HbA1c se mantuvieron por encima de 10 %, salvo las dos últimas determinaciones, que mostraron valores significativamente menores que los meses anteriores, y fueron independientes de las variables sexo, tiempo de evolución, edad de diagnóstico y dosis promedio diaria de insulina por kilogramo de peso corporal. Conclusiones: una relación clínica adecuada y la mejoría en el cumplimiento del tratamiento fueron elementos decisivos en la mejoría del control metabólico en nuestros pacientes.Introduction: the metabolic control is the main objective of the diabetes mellitus treatment. Objective: to characterize the metabolic control in a group of

  3. Pielonefritis, colecistitis y cistitis enfisematosas en paciente con diabetes mellitus descompensada

    OpenAIRE

    Zaragoza S,Tahitiana Abelina; Osnaya M,Humberto; Mondragón C,Marco Antonio; Sánchez R,Rubén Darío

    2012-01-01

    Introducción: La Pielonefritis enfisematosa es una infección necrotizante caracterizada por la producción de gas, que habitualmente se ubica en el parénquima renal, las vías urinarias y los tejidos retroperi-toneales. Cuando el gas es abundante puede escapar siguiendo las venas renales y acumularse en las venas hepáticas, y el resto del sistema. La E. coli es el patógeno más frecuente. Caso clínico: Presentamos el caso de paciente femenina de 62 años, diabética que ingresa con sintomatología ...

  4. Diabetes Mellitus en el adulto mayor

    OpenAIRE

    Guerrero-Godínez, Juan; Barragán-Vigil, Ana; Navarro-Macias, Carmen; Murillo-Bonilla, Luis; Uribe-González, Paul; Sánchez-Cruz, Martha

    2017-01-01

    La Diabetes Mellitus, una enfermedad crónica que afecta a todo el mundo siendo nuestro país México, el primer lugar con esta enfermedad, su incidencia aumenta junto con la edad hasta un 20% en personas mayores de 60 años todos ellos susceptibles a síndromes geriátricos, con posibles repercusiones ya sea por falta de control de niveles de glicemia o por un exceso en el control. El objetivo de esta revisión no sistemática es concientizar a la población general de la diabetes mellitus y el conte...

  5. Elevada frecuencia de neuropatía periférica en pacientes con Diabetes mellitus tipo 2 de un hospital general de Lima-Perú

    Directory of Open Access Journals (Sweden)

    Ray Ticse

    2013-04-01

    Full Text Available Objetivos: Determinar la frecuencia de neuropatía periférica en pacientes con diabetes mellitus tipo 2 y la correlación entre la evaluación clínica con el estudio de la velocidad de conducción nerviosa (VCN. Material y métodos: Estudio descriptivo, transversal. Se evaluaron 62 pacientes con diagnóstico de diabetes mellitus tipo 2. Se utilizó el Michigan Neuropathy Screening Instrument (MNSI, el Michigan Diabetic Neuropatic Score (MDNS y el estudio de VCN. Además se describieron las variables demográficas, antropométricas y de laboratorio. Resultados: La frecuencia de neuropatía periférica fue 96,8% según la VCN y 45% según el MNSI. La correlación entre el número de nervios afectados según VCN y el score MDNS fue moderada (Spearman r=0,59; p<0,001. Conclusiones: Existe una elevada frecuencia de neuropatía periférica en los pacientes diabéticos evaluados y no hubo buena correlación entre VCN y el score MDNS.

  6. Factores asociados a la calidad de vida relacionada a la salud en pacientes con cardiopatía coronaria y diabetes mellitus.

    Directory of Open Access Journals (Sweden)

    Moises Barrantes

    2010-07-01

    Full Text Available mellitus. Material y métodos: Se utilizó el cuestionario (SF-36 y se incluyeron 70 pacientes diabéticos y 140 no diabéticos admitidos por un evento coronario agudo en la Unidad Coronaria del Hospital Nacional Edgardo Rebagliati Martins entre diciembre 2006 y diciembre 2007. Se realizó análisis multivariado para determinar los factores asociados a los dos componentes sumarios de la calidad de vida relacionada a la salud (CVRS y si la diabetes mellitus era un factor independiente. Resultados: Ambos grupos de estudio tuvieron, en general, similares características basales. En la estimación de la calidad de vida global, los pacientes diabéticos tuvieron índices significativamente menores de percepción solamente en el componente sumario físico. Se construyeron modelos de regresión lineal múltiple entre ambos componentes sumario de la CVRS y las variables de estudio, identificándose la edad avanzada, el género femenino y la diabetes mellitus como los principales factores asociados a la CVRS. Conclusión: La edad, el género, el sobrepeso y la obesidad, la hemoglobina glucosilada, la diabetes mellitus, el antecedente de enfermedad coronaria, las comorbilidades, el estado civil y el nivel socioeconómico son factores asociados a la CVRS en pacientes con cardiopatía coronaria y diabetes mellitus.(Rev Med Hered 2010;21:118-127.

  7. Diabetes mellitus and Parkinson disease.

    Science.gov (United States)

    Pagano, Gennaro; Polychronis, Sotirios; Wilson, Heather; Giordano, Beniamino; Ferrara, Nicola; Niccolini, Flavia; Politis, Marios

    2018-05-08

    To investigate whether diabetes mellitus is associated with Parkinson-like pathology in people without Parkinson disease and to evaluate the effect of diabetes mellitus on markers of Parkinson pathology and clinical progression in drug-naive patients with early-stage Parkinson disease. We compared 25 patients with Parkinson disease and diabetes mellitus to 25 without diabetes mellitus, and 14 patients with diabetes mellitus and no Parkinson disease to 14 healthy controls (people with no diabetes mellitus or Parkinson disease). The clinical diagnosis of diabetes mellitus was confirmed by 2 consecutive fasting measurements of serum glucose levels >126 mL/dL. Over a 36-month follow-up period, we then investigated in the population with Parkinson disease whether the presence of diabetes mellitus was associated with faster motor progression or cognitive decline. The presence of diabetes mellitus was associated with higher motor scores ( p Parkinson disease. In patients with diabetes but without Parkinson disease, the presence of diabetes mellitus was associated with lower striatal dopamine transporter binding ( p Parkinson disease, the presence of diabetes mellitus was associated with faster motor progression (hazard ratio = 4.521, 95% confidence interval = 1.468-13.926; p Parkinson-like pathology, and when present in patients with Parkinson disease, can induce a more aggressive phenotype. © 2018 American Academy of Neurology.

  8. Propiedades psicométricas de la Escala de Locus de Control de la Salud en Dios en una muestra de mexicanos con diabetes mellitus tipo 2

    Directory of Open Access Journals (Sweden)

    Vianey Guadalupe Argüelles Nava

    2017-12-01

    Full Text Available En este estudio se obtuvo evidencia de validez y confiabilidad de la escala de Locus de Control de la Salud en Dios (GLHC en una muestra de 539 adultos mexicanos con diabetes mellitus tipo 2. El análisis de validez se basó en el análisis del contenido de los ítems y de la estructura interna del GLHC. El primer procedimiento estuvo a cargo de seis expertos, quienes evaluaron la pertinencia de la adaptación de los ítems. El segundo procedimiento fue un análisis factorial confirmatorio de grupo múltiple, de acuerdo al sexo y edad, a fin de evaluar la invarianza de medición del GLHC. Finalmente, la confiabilidad fue calculada mediante los coeficientes ω y H. El análisis factorial confirmatorio demostró una estructura de un solo factor con seis ítems, interpretable para la población de estudio con invarianza de medición por sexo, aunque deben tomarse precauciones al interpretar comparaciones por grupos de edad. La confiabilidad del constructo obtuvo magnitudes elevadas (>.90. Los resultados indican que la GLHC puede brindar información válida y confiable para valorar el locus de control de la salud en Dios para mexicanos con diabetes mellitus tipo 2.

  9. History of diabetes mellitus.

    Science.gov (United States)

    Ahmed, Awad M

    2002-04-01

    Clinical features similar to diabetes mellitus were described 3000 years ago by the ancient Egyptians. The term "diabetes" was first coined by Araetus of Cappodocia (81-133AD). Later, the word mellitus (honey sweet) was added by Thomas Willis (Britain) in 1675 after rediscovering the sweetness of urine and blood of patients (first noticed by the ancient Indians). It was only in 1776 that Dobson (Britain) firstly confirmed the presence of excess sugar in urine and blood as a cause of their sweetness. In modern time, the history of diabetes coincided with the emergence of experimental medicine. An important milestone in the history of diabetes is the establishment of the role of the liver in glycogenesis, and the concept that diabetes is due to excess glucose production Claude Bernard (France) in 1857. The role of the pancreas in pathogenesis of diabetes was discovered by Mering and Minkowski (Austria) 1889. Later, this discovery constituted the basis of insulin isolation and clinical use by Banting and Best (Canada) in 1921. Trials to prepare an orally administrated hypoglycemic agent ended successfully by first marketing of tolbutamide and carbutamide in 1955. This report will also discuss the history of dietary management and acute and chronic complications of diabetes.

  10. EFECTOS DE UN PROGRAMA COGNITIVO COMPORTAMENTAL SOBRE LOS NIVELES DE ESTRÉS Y GLUCEMIA EN PACIENTES CON DIABETES MELLITUS TIPO II

    OpenAIRE

    Delgado Maigual, Luis Carlos; Hidalgo Villarreal, Guillermo Andrés; Villalobos Galvis, Fredy Hernán

    2011-01-01

    En este estudio se determinaron los efectos de la aplicación de un programa cognitivo-comportamental sobre los niveles de estrés y glucemia en pacientes con diabetes mellitus tipo II de la Fundación Hospital San Pedro de San Juan de Pasto. Para ello, se determinaron los niveles de estrés y glucemia antes de la aplicación del programa de intervención; luego se diseñó y aplicó el programa a los participantes (el cual está sustentado en el modelo procesual de estrés de Lazarus y Folkman) y final...

  11. Síndrome metabólico en familiares de primer grado de pacientes con diabetes mellitus tipo 2 Metabolic syndrome in first degree relatives of patients with diabetes mellitus 2

    Directory of Open Access Journals (Sweden)

    Raúl Orlando Calderín Bouza

    2005-12-01

    Full Text Available Se realizó un estudio descriptivo y transversal de 340 personas divididas en 2 grupos, con y sin antecedentes patológicos familiares de diabetes mellitus tipo 2 (APF de DM2, con el objetivo de detectar si las que presentaban APF de DM2 tenían más hiperinsulinemia, presencia de síndrome metabólico, factores de riesgo cardiovascular asociados y lesión de órganos diana, expresados en hipertrofia del ventrículo izquierdo de los sujetos que no tenían dicho antecedente. Se obtuvo como resultado que la hiperinsulinemia estuvo presente en 96 pacientes con APF de DM2 (56,5 % y una significación de p = 0,001. El síndrome metabólico fue más frecuente en las personas con APF DM2 (90 para un 52,9 % y una significación de p = 0,000. La hipertrigliceridemia fue el marcador por excelencia del síndrome metabólico y el factor de riesgo que con más significación estadística se asoció a los sujetos con APF de DM2 (96: 52,9 % y una significación de p = 0,000. La hipertrofia ventricular izquierda (HVI se asoció como expresión de lesión de órganos diana a los sujetos con APF de DM2 (36: 21,2 % y una significación de p = 0,043. Concluimos que los sujetos con APF de DM2 son más propensos a tener hiperinsulinemia, al síndrome metabólico, a factores de riesgo cardiovascular y a lesión de órgano diana en comparación con los que no tienen dicho antecedente.A cross-sectional descriptive study of 340 persons assigned to two groups, with and without family history of diabetes mellitus type 2 (DM2, was carried out. The objective was to detect whether those persons with family history of DM2 had more hyperinsulemia, metabolic syndrome, associated cardiovascular risk factors and target organ lesions, expressed in left ventricle hypertrophy, than subjects without diabetes family history. The result was that hyperinsulemia was present in 96 patients with family history of DM2 (56,5 % and significance level of p= 0,001. Metabolic syndrome was more

  12. El dibujo como exponente de las percepciones sobre la enfermedad en niños y niñas con diabetes mellitus Drawing as an exponent of the perceptions of the disease in boys and girls with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Teresa Argüelles

    2006-04-01

    Full Text Available El diagnóstico de la diabetes mellitus (DM en la infancia tiene un impacto negativo en los niños y niñas, por lo que constituye una premisa importante conocer el significado que ellos le atribuyen a la enfermedad. El dibujo resulta una técnica eficaz para conocer el significado de un tema particular en la infancia. El objetivo del presente trabajo fue explorar la utilidad del dibujo como medio de expresión de las percepciones sobre la enfermedad en un grupo de niños con DM, con el fin de valorar su uso en el proceso educativo. Formaron parte del estudio 20 niños/as con DM: 10 ingresados en la sala pediátrica y 10 participantes en una actividad clínico-educativa ambulatoria (convivencia. A todos se les invitó a realizar un dibujo con el tema “La diabetes y yo”. Se hizo un análisis de contenido y gráfico (referido al uso del color de cada dibujo elaborado. La técnica del dibujo fue bien aceptada por los niños/as del estudio. En el grupo del ingreso hospitalario los temas más representados fueron las restricciones dietéticas (70 % y la inyección de insulina (50,0, mientras que en el grupo de la convivencia fueron el control metabólico (50,0 y el ejercicio físico (50,0. Temas como la dieta balanceada, educación, recreación e higiene solo se representaron en el grupo de la convivencia. En los dibujos los niños reflejaron elementos claves del tratamiento de la DM y la manera en que cada uno los percibía según el momento que estaban viviendo.The diagnosis of diabetes mellitus (DM in childhood has a negative impact on boys and girls. That's why, it is important to know what this disease means to them. Drawing is an efficient technique to know the meaning of a particular topic in childhood. The aim of this paper was to explore the usefulness of drawing as a means of expression of the perceptions of the disease in a group of children with DM in order to assess its use in the educative process. 20 boys and girls with diabetes

  13. Desarrollo de diabetes mellitus en pacientes con tolerancia a la glucosa alterada: Seguimiento de 18 años Development of diabetes mellitus in patients with impaired glucose tolerance: An 18-year follow-up

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    Pedro Perich Amador

    2002-08-01

    Full Text Available Se realizó un estudio prospectivo en 84 pacientes con diagnóstico de “tolerancia a la glucosa alterada” (TGA, desde hace 18 años, para conocer la prevalencia de diabetes mellitus (DM e identificar factores clínicos o metabólicos que pudieran estar asociados a la evolución desfavorable de esta afección. Se encontró que de los 114 sujetos con TGA que componían el grupo inicial, 25 (22 % habían fallecido. Se revisaron sus características iniciales y se halló que tenían un promedio de 10 años de edad más que los no fallecidos y frecuencia significativamente mayor de signos electrocardiográficos de cardiopatía isquémica, hipertensión arterial, hipercolesterolemia y hábito de fumar. En los 84 sujetos en los que se estudió la evolución metabólica, más de la mitad (53,6 % evolucionó a la DM, el 23,8 % se mantuvo con TGA y el 22,6 % restante, presentó tolerancia a la glucosa normal. No hubo relación entre las características clínicas en el estudio inicial y el tipo de evolución. Los sujetos que tenían al inicio “trastornos de la regulación de la glucemia en ayunas” (cifras ³ 6,1 mmol/L,18 años después presentaron mayor frecuencia de diabetes manifiesta que el resto, diferencia no significativa estadísticamente. Se concluyó que la TGA es un factor de riesgo importante para la DM2, y los trastornos de la regulación de la glucemia en ayunas, un estado avanzado de esta situación de riesgo por lo que se necesitan indicadores clínicos y metabólicos, asociados a la evolución desfavorable, que permitan establecer precozmente el nivel de riesgo de los sujetos con TGA.A prospective study was conducted among 84 patients that were diagnosed “impaired glucose tolerance” (IGT 18 years ago in order to know the prevalence of diabetes mellitus (DM and to identify clinical or metabolic factors that may be associated to an unfavorable evolution of this affection. It was found that of the 114 subjects with IGT that were

  14. Educación para la salud en el niño que debuta con Diabetes mellitus tipo 1

    OpenAIRE

    Fernandez Ortiz, Jose Antonio

    2016-01-01

    La diabetes mellitus tipo 1 (DM1) es una enfermedad crónica producida en el páncreas por la ausencia de insulina debido a un origen autoinmune, suele debutar en la infancia y su incidencia sigue aumentando. Los cuidados derivados de información escasa o incorrecta suponen graves problemas de salud. La educación sanitaria en pacientes diabéticos debe proporcionar las herramientas necesarias y así alcanzar unos conocimientos adecuados para el autocuidado de esta enfermedad. Grado en Enfermer...

  15. Cardiovascular consequences of diabetes mellitus

    NARCIS (Netherlands)

    C.A. Baan (Caroline)

    1999-01-01

    textabstractDiabetes mellitus comprises a clinically and genetically heterogeneous group of disorders that have one common feature: abnormally high levels of glucose in the blood. The most common form is non-insulin dependent diabetes mellitus (NlDDM); about 80-90% of all diabetic patients has

  16. Diversidad y universalidad como respuesta a pie diabético en paciente paquistaní con diabetes mellitus tipo 2 desde Atención Primaria

    Directory of Open Access Journals (Sweden)

    Montserrat Brugada Faura

    Full Text Available Siguiendo las enseñanzas de Madeleine Leininger sobre los conceptos de su modelo transcultural, buscamos una respuesta en el entorno de la Atención Primaria al caso que nos ocupa de una lesión ulcerosa en pie izquierdo, de etiología desconocida, en paciente paquistaní con diabetes mellitus tipo 2. Hallando la respuesta mediante la adaptación de similitudes de riesgo en el entorno de esta enfermedad, comunes en todas las culturas, y cuyas diferencias estriban en la localización de la úlcera y su factor desencadenante. Anómalas en nuestra cultura al estar relacionada con sus prácticas culturales.

  17. The burden of gestational diabetes mellitus in Jamaican women with a family history of autosomal dominant type 2 diabetes La carga de la diabetes mellitus gestacional en mujeres de Jamaica con antecedentes familiares de diabetes autosómica dominante tipo 2

    Directory of Open Access Journals (Sweden)

    Rachael R. Irving

    2008-02-01

    Full Text Available OBJECTIVES: To determine if Jamaican women of African descent with a family history of early onset autosomal dominant type 2 diabetes have greater odds of developing gestational diabetes mellitus (GDM than those without a family history of the disease. METHODS: A comparative study was conducted of two groups of pregnant Jamaican women: the first with a family history of early onset autosomal dominant type 2 diabetes; the second with no history of the disease. Incidence, odds for developing GDM, and metabolic profiles in first and second trimesters were assessed using SPSS 11.5 (SPSS Inc., Chicago, Illinois, United States. RESULTS: The incidence of GDM was 12.0 % in women with a family history of early onset autosomal dominant type 2 diabetes and 1.5% in women without a family history of the disease (P OBJETIVOS: Determinar si las mujeres jamaicanas de ascendencia africana con antecedentes familiares de inicio temprano de diabetes autosómica dominante tipo 2 tienen mayor probabilidad de desarrollar diabetes mellitus gestacional (DMG que las que no tienen esos antecedentes familiares. MÉTODOS: Se realizó un estudio comparativo con dos grupos de mujeres jamaicanas embarazadas: el primero con mujeres que tenían antecedentes familiares de inicio temprano de diabetes autosómica dominante tipo 2 y el segundo con mujeres sin antecedentes familiares de esa enfermedad. Se empleó el programa SPSS v. 11.5 (SPSS Inc., Chicago, Illinois, Estados Unidos de América para analizar los resultados y calcular la incidencia, la probabilidad de desarrollar DMG y los perfiles metabólicos en el primer y el segundo trimestres de gestación. RESULTADOS: La incidencia de DMG fue de 12,0% en las mujeres con antecedentes familiares de inicio temprano de diabetes autosómica dominante tipo 2 y de 1,5% en las mujeres sin antecedentes familiares de esa enfermedad (P < 0,05. Las mujeres del primer grupo tuvieron nueve veces más probabilidades de desarrollar DMG que las

  18. Therapeutic itinerary of the family and adolescent with type i mellitus diabetes El itinerario terapéutico del adolescente con diabetes mellitus tipo i y sus familiares Itinerário terapêutico do adolescente com diabetes mellitus tipo 1 e seus familiares

    Directory of Open Access Journals (Sweden)

    Mariza Maria Serafim Mattosinho

    2007-12-01

    Full Text Available This is a qualitative assistential convergent study. Its main objective is to understand the therapeutic itinerary of adolescents with type 1 mellitus diabetes, as well as that of their families. The sample was composed of adolescents, between 15 and 25 years old, involved with a health institution in Florianópolis through the Health Care model that includes professional, family, and popular subsystems. Data were obtained through in-depth interviews and field observation of 20 people (relatives and adolescents with diabetes. The data analysis included data codification and categorization. Two categories were constructed: Decisions and negotiations about health, care and treatment; and the journey through the three subsystems of health care. The study permitted to understand that the treatment and care within the professional subsystem are not the only ones available. There are different practices in health performed from the evaluation each family makes, of what they believe adequate for their adolescent with diabetes.Estudio de naturaleza cualitativa, de tipo convergente-asistencial, tuvo como objetivo comprender el camino terapéutico de los adolescentes con diabetes mellitus tipo I y sus familiares, vinculados a una institución de salud de Florianópolis, entre las edades de 15 y 25 años, a través del modelo del Cuidado para la Salud, que incluye los subsistemas profesional, familiar y popular. Los datos fueron obtenidos a través de la entrevista en profundidad y la observación de campo con 20 personas (familiares y adolescentes con diabetes. El análisis incluye la codificación y la categorización de los datos. Fueron construidos dos categorias: Las decisiones y negociaciones sobre la salud, los cuidados y los tratamientos y El percurso en los tres subsistemas de la salud. El estudio permitió comprender que los tratamientos y los cuidados del subsistema profesional no son los únicos, existiendo diferentes prácticas en la salud que

  19. Detección precoz de pacientes con riesgo de diabetes mellitus en la atención secundaria de salud

    Directory of Open Access Journals (Sweden)

    Diamara Rodríguez Pérez

    2017-10-01

    Full Text Available Introducción: los pacientes prediabéticos poseen riesgo de desarrollo de diabetes mellitus. Su diagnóstico precoz puede prevenir la aparición de esta condición metabólica. Objetivo: identificar la prevalencia de pacientes con prediabetes durante el chequeo médico y la caracterización de algunos aspectos clínicos y epidemiológicos. Métodos: se realizó un estudio observacional, descriptivo y transversal en el Hospital Militar Docente Dr. Mario Muñoz Monroyde Matanzas. La muestra estuvo constituida por 434 individuos a los que se les diagnosticó prediabetes. Resultados: predominó el sexo masculino (88 %, siendo más frecuente para ambos sexos el grupo de edad de 45 a 54 años. En la categoría de glicemia en ayunas alterada hubo 234 pacientes (54 %, 139 (32 % con tolerancia a la glucosa alterada y 61 (14 % portadores de prediabetes doble. El factor de riesgo más frecuente fue la dislipidemia, seguido del índice de masa corporal mayor e igual de 25 y la edad mayor de 45 años. En las enfermedades concomitantes predominó la hipertensión arterial esencial (68 % y la cardiopatía isquémica (25 %. En el estado nutricional predominaron los sobrepesos y obesos con el 54 y 47 %, respectivamente. Conclusiones: en la atención secundaria de salud fue detectada precozmente una elevada prevalencia de pacientes con riesgo de desarrollo de diabetes mellitus tipo 2 que desconocían su condición.

  20. Alcoholism and Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Soo-Jeong Kim

    2012-04-01

    Full Text Available Chronic use of alcohol is considered to be a potential risk factor for the incidence of type 2 diabetes mellitus (T2DM, which causes insulin resistance and pancreatic β-cell dysfunction that is a prerequisite for the development of diabetes. However, alcohol consumption in diabetes has been controversial and more detailed information on the diabetogenic impact of alcohol seems warranted. Diabetes, especially T2DM, causes dysregulation of various metabolic processes, which includes a defect in the insulin-mediated glucose function of adipocytes, and an impaired insulin action in the liver. In addition, neurobiological profiles of alcoholism are linked to the effects of a disruption of glucose homeostasis and of insulin resistance, which are affected by altered appetite that regulates the peptides and neurotrophic factors. Since conditions, which precede the onset of diabetes that are associated with alcoholism is one of the crucial public problems, researches in efforts to prevent and treat diabetes with alcohol dependence, receives special clinical interest. Therefore, the purpose of this mini-review is to provide the recent progress and current theories in the interplay between alcoholism and diabetes. Further, the purpose of this study also includes summarizing the pathophysiological mechanisms in the neurobiology of alcoholism.

  1. Personas con diabetes mellitus tipo 2 y su capacidad de agencia de autocuidado, Cartagena Pessoas com diabete mellitus tipo 2 e sua capacidade de agência de autocuidado, Cartagena Patients with Type 2 Mellitus Diabetes and their Self-Care Agency Capacity, Cartagena

    Directory of Open Access Journals (Sweden)

    Arleth Herrera Lían

    2012-07-01

    Full Text Available Contexto: La diabetes mellitus tipo 2 se constituye en un problema de salud pública por las repercusiones bio-psicosociales, la presencia de complicaciones neurovasculares y metabólicas en la persona que la padece. Enfermería cumple un papel importante a través de la educación y la capacitación. Objetivo: Identificar la capacidad de agencia de autocuidado de las personas con diagnóstico de diabetes mellitus tipo 2, inscritos en los programas de control de diabetes en 19 UPAS de Cartagena. Metodología: diseño descriptivo con abordaje cuantitativo, en una muestra de 225 adultos de ambos sexos, seleccionados en forma aleatoria. La capacidad de agencia de autocuidado se identificó con la escala de Valoración de las capacidades de autocuidado, desarrollada por Isenberg y Everest, traducida al español por Gallegos y adaptada por la Universidad Nacional de Colombia. Para presentar los datos se utilizó la estadística descriptiva, los resultados se presentan en tablas y gráficas. Resultados: Predominó el sexo femenino (68,4 %; la unión libre (59,1 %; escolaridad (50,6 % con básica primaria; bajos ingresos económicos (menos de un salario mínimo mensual vigente, 34.7 %. Al valorar la capacidad de agencia de autocuidado, el 73.8 % de los pacientes obtuvo una calificación de muy buena (76-100 %, según escala. Al valorar los aspectos comprendidos en la escala se encontró que más del 50 % de las personas siempre sacan tiempo para ellos, piden explicación sobre su salud, examinan su cuerpo para ver si hay cambios y conservan un ambiente limpio. Conclusiones: El apoyo social recibido por los pacientes con diabetes mellitus tipo 2 y las prácticas de higiene personal y del entorno, el conocimiento y la adherencia a la dieta, permiten a los pacientes una buena capacidad de agencia de autocuidado.Contexto: A diabete mellitus tipo 2 se configura como um problema de saúde pública por conta das repercussões biopsicossociais e da presen

  2. Radiation retinopathy in diabetes mellitus

    International Nuclear Information System (INIS)

    Dhir, S.P.; Joshi, A.V.; Banerjee, A.K.

    1982-01-01

    A case of radiation retinopathy in a diabetic individual who received a total dose of 45 Gy for lymphoblastic lymphoma of the orbit is reported. The relationship between radiation retinopathy and diabetes mellitus is discussed. (Auth.)

  3. Construcción y validación inicial de un instrumento para medir el estilo de vida en pacientes con diabetes mellitus tipo 2

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    López-Carmona Juan Manuel

    2003-01-01

    Full Text Available OBJETIVO: Construir y validar un instrumento específico para medir el estilo de vida en los pacientes con diabetes mellitus tipo 2. MATERIAL Y MÉTODOS: Entre marzo de 2001 y abril de 2002 se hizo un estudio observacional, longitudinal y prospectivo en unidades de medicina familiar de la delegación Estado de México Oriente, del Instituto Mexicano del Seguro Social. Se diseñó un instrumento de autoadministración, denominado instrumento para medir el estilo de vida en diabéticos, el cual fue sometido a revisión por un panel multidisciplinario de expertos para determinar su validez lógica y de contenido. Se aplicó el instrumento en dos días diferentes a 412 sujetos adultos con diabetes mellitus. Fueron depurados los ítems considerando la frecuencia de selección de sus opciones de respuesta, su correlación ítem-total y su carga significativa en los dominios durante el análisis factorial. RESULTADOS: Completaron el estudio 389 (94.7% sujetos. Los coeficientes de correlación intra-clase para la validez lógica y de contenido fueron de 0.91 y 0.95, respectivamente. Después de la depuración de ítems se obtuvo un instrumento conformado por 25 preguntas cerradas, distribuidas en siete dominios: nutrición, actividad física, consumo de tabaco, consumo de alcohol, información sobre diabetes, emociones y adherencia terapéutica. El a de Cronbach para la calificación total fue de 0.81 y el coeficiente de correlación test-retest de 0.84. CONCLUSIONES: El instrumento para medir el estilo de vida en diabéticos es el primer cuestionario específico para sujetos con diabetes mellitus tipo 2 y tiene validez aparente, validez de contenido y buen nivel de consistencia.

  4. Osteoporosis and diabetes mellitus

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    Andrea Montagnani

    2013-03-01

    Full Text Available Introduction: Diabetes mellitus (DM and osteoporotic fractures are major causes of mortality and morbidity in older subjects. Recent reports have revealed close association between fracture risk and DM types 1 and 2 (DM1 and DM2, respectively. Aim of this review is to highlight the importance of these diseases in the elderly and examine certain etiopathogenetic aspects of DM associated osteoporosis, which could be useful in management of diabetic patients. Materials and methods: We searched the Embase and PubMed databases using diabetes, osteoporosis, and bone mineral density (BMD as search terms and 1989-2009 as publication dates. Discussion: The risk of fractures seems to be increased in both types of DM although DM2 seems to be associated with normal-high BMDs compared with the normal population. This apparent paradox could reflect greater bone frailty in diabetic patients that are unrelated to adipose tissue, hyperinsulinemia, deposition of advanced glycosylation end products in collagen, reduced serum IGF-1 levels, hypercalciuria, renal failure, microangiopathy, and/or inflammation. Diabetic patients’ propensity to fall and multiple comorbidities might also explain their higher fracture rates. The effects of drugs that inhibit bone resorption in diabetic patients are probably similar to those obtained in nondiabetics although there is little information on this issue. In general, effective treatment of diabetes has positive effects on bone metabolism. Metformin acts directly on bone tissue, reducing AGE accumulation, and insulin has direct effects on osteoclast activity. In contrast, the thiazolidinediones seem to have negative effects since they orient mesenchymal progenitor cell differentiation toward adipose rather than bone tissue. Incretin therapy is a newer approach that appears to modify interactions between nutrition and bone turnover (e.g., postprandial suppression of bone resorption. Conclusions: Better understanding of how

  5. Efecto de la suplementación con Vimang® sobre indicadores de estrés oxidativo en jóvenes con diabetes mellitus tipo 1 Effect of Vimang® supplementation on oxidative stress markers in young patients with type 1 diabetes mellitus

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    Adrián Luis Escobar Aedo

    2011-08-01

    Full Text Available Introducción: el estrés oxidativo juega un papel fundamental en la fisiopatogenia de las complicaciones de la diabetes mellitus. Se ha empleado con éxito el producto natural antioxidante Vimang® en enfermedades caracterizadas por incremento del estrés oxidativo. Objetivo: evaluar el efecto del Vimang® sobre el estado redox, en personas jóvenes con diabetes mellitus tipo 1. Métodos: se realizó un ensayo clínico fase II, unicéntrico, aleatorizado y controlado, en el que se evaluó la eficacia antioxidante del Vimang® en tabletas, en jóvenes con diabetes mellitus tipo 1. Fueron incluidos 50 pacientes, que se distribuyeron en 2 grupos de 25 cada uno, que recibieron Vimang® en tabletas de 300 mg cada 8 h y placebo, respectivamente. Se evaluó el control glucémico a través de la hemoglobina glucosilada, se realizó un lipidograma completo y determinaciones hemoquímicas. Fueron evaluadas las variables de daño por estrés oxidativo: potencial de peroxidación, hidroperóxidos totales, productos avanzados de la oxidación de proteínas, malonilaldehído y del antioxidante endógeno glutatión reducido. Las determinaciones se realizaron antes, y a los 3 meses de la intervención. Los grupos fueron comparados entre sí, en los dos tiempos, así como internamente con respecto al estado basal previo a la suplementación con Vimang® o placebo. Resultados: el potencial de peroxidación se incrementó a los 3 meses en ambos grupos (pIntroduction: the oxidative stress plays a fundamental role in the pathogenesis of diabetes mellitus complications. Vimang® (a natural antioxidant product has been successfully used diseases characterized by an increase of oxidative stress. Objective: to assess the effect of Vimang® on the redox state in young people presenting with type 1 diabetes mellitus. Methods: a phase II clinical, randomized, controlled unicenter trial to assess the antioxidant effectiveness tablets Vimang® in young people with type 1

  6. Type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    DeFronzo, Ralph A; Ferrannini, Ele; Groop, Leif

    2015-01-01

    Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular complications (including retinopathy, nephropathy and neuropathy) and macrovascular complications (such as cardiovascular...... that multiple antidiabetic agents, used in combination, will be required to maintain normoglycaemia. The treatment must not only be effective and safe but also improve the quality of life. Several novel medications are in development, but the greatest need is for agents that enhance insulin sensitivity, halt...

  7. Gestational Diabetes Mellitus

    DEFF Research Database (Denmark)

    McIntyre, H David; Jensen, Dorte M; Jensen, Richard C

    2018-01-01

    OBJECTIVE: To define the prevalence and pregnancy outcomes related to elevated fasting venous plasma glucose (FVPG) in a Danish pregnancy cohort. RESEARCH DESIGN AND METHODS: This was an observational cohort study including 1,516 women without gestational diabetes mellitus (GDM) by Danish criteria....... FVPG measured at 28 weeks' gestation was related to pregnancy outcomes. RESULTS: With use of the World Health Organization 2013 threshold of FVPG ≥5.1 mmol/L, 40.1% of the cohort qualified as having GDM. There was no evidence of excess fetal growth, hypertension in pregnancy, or caesarean delivery...

  8. Pharmacogenomics in diabetes mellitus

    DEFF Research Database (Denmark)

    Zhou, Kaixin; Pedersen, Helle Krogh; Dawed, Adem Y.

    2016-01-01

    . We highlight mechanistic insights from the study of adverse effects and the efficacy of antidiabetic drugs. The identification of extreme sulfonylurea sensitivity in patients with diabetes mellitus owing to heterozygous mutations in HNF1A represents a clear example of how pharmacogenetics can direct...... patient care. However, pharmacogenomic studies of response to antidiabetic drugs in T2DM has yet to be translated into clinical practice, although some moderate genetic effects have now been described that merit follow-up in trials in which patients are selected according to genotype. We also discuss how...

  9. Diabetes Mellitus and Osteoporosis

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    Dilek Durmuş

    2005-09-01

    Full Text Available Osteoporosis is a condition of bone fragility resulting from micro-architectural deterioration and decreased bone mass. Studies on the presence of a generalized osteoporosis related to diabetes mellitus (DM are few and controversial. Factors associated with osteoporosis diabetes in which may account for the patogenesis of diabetic bone loss have been studied. This article will review the relevant litarature relating to diabetes and osteoporosis including cellular and animal models. These studies include vascular and neuropathic mechanism, poor glisemic control, abnormalities of calcium and vitamin D metabolism and hypercalciuria with secondary increase in parathyroid hormone secretion, the role of insülin and insülin like growth factor I. It appears that there is a great deal of variability in the bone mineral density and fracture rates in both type I and type II DM. This may reflect multiple factors such as the population, age, duration of diabetes and insülin use. There is need for further longitudinal studies, including the incidence and risk factors for osteoporosis in DM.

  10. Diabetes mellitus in elderly

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    Farida Chentli

    2015-01-01

    Full Text Available Diabetes mellitus (DM frequency is a growing problem worldwide, because of long life expectancy and life style modifications. In old age (≥60–65 years old, DM is becoming an alarming public health problem in developed and even in developing countries as for some authors one from two old persons are diabetic or prediabetic and for others 8 from 10 old persons have some dysglycemia. DM complications and co-morbidities are more frequent in old diabetics compared to their young counterparts. The most frequent are cardiovascular diseases due to old age and to precocious atherosclerosis specific to DM and the most bothersome are visual and cognitive impairments, especially Alzheimer disease and other kind of dementia. Alzheimer disease seems to share the same risk factors as DM, which means insulin resistance due to lack of physical activity and eating disorders. Visual and physical handicaps, depression, and memory troubles are a barrier to care for DM treatment. For this, old diabetics are now classified into two main categories as fit and independent old people able to take any available medication, exactly as their young or middle age counterparts, and fragile or frail persons for whom physical activity, healthy diet, and medical treatment should be individualized according to the presence or lack of cognitive impairment and other co-morbidities. In the last category, the fundamental rule is "go slowly and individualize" to avoid interaction with poly medicated elder persons and fatal iatrogenic hypoglycemias in those treated with sulfonylureas or insulin.

  11. Acolhimento e vínculo na humanização do cuidado de enfermagem às pessoas com diabetes mellitus Acogimiento y vínculo en la humanización del cuidado de enfermería a personas con diabetes mellitus User embracement and attachment in the humanization of nursing care for people with diabetes mellitus

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    Cecilia Arruda

    2012-10-01

    Full Text Available Pesquisa qualitativa que objetivou avaliar o acolhimento e o vínculo na prática da humanização dos cuidados de enfermagem às pessoas com Diabetes Mellitus em um serviço ambulatorial público. O suporte teórico foi a Política Nacional da Humanização do Ministério da Saúde/Brasil. A coleta de dados ocorreu em entrevistas semiestruturadas realizadas com vinte pessoas com diabetes tipo 1 ou tipo 2, entre março e maio de 2010. A análise resultou em quatro categorias que exploram a escuta e o diálogo, o relacionamento, a resolutividade e o acesso aos serviços de saúde. As pessoas com diabetes reconhecem o acolhimento e o vínculo como partes da atenção humanizada recebida, que se destaca pela valorização da dimensão subjetiva dos usuários.Investigación cualitativa que objetivó evaluar el acogimiento y el vínculo en los cuidados de enfermería a las personas con diabetes mellitus en un servicio ambulatorio público. El soporte teórico fue la Política Nacional de Humanización del Ministerio de Salud/Brasil. La recolección de los datos empleó entrevistas semi estructuradas realizadas con veinte personas con diabetes tipo 1 o tipo 2, entre marzo y mayo de 2010. El análisis resultó en cuatro categorías que exploran: escucha y diálogo, relación, resolución y acceso. Las personas con diabetes reconocen el acogimiento y el vínculo como partes de la atención humanizada recibida, la cual se destaca por la valorización de la dimensión subjetiva de los usuarios.It is a qualitative research, which aimed to evaluate the user embracement and attachment in the humanization of nursing care for people with Diabetes Mellitus in a public specialized outpatient service. The theoretical support was the National Policy of Humanization of the Health Ministry / Brazil. Data was collected through semi-structured interviews with twenty people with type 1 or type 2 diabetes, between 2010 March and May. The analysis resulted in four

  12. Asociación de la neuropatía autonómica cardiovascular y el intervalo QT prolongado con la morbimortalidad cardiovascular en pacientes con diabetes mellitus tipo 2 Association of cardiovascular autonomic neuropathy and prolonged QT interval with cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus

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    Ray Ticse Aguirre

    2011-03-01

    Full Text Available Con el objetivo de evaluar la relación entre la neuropatía autonómica cardiovascular (NACV y el intervalo QT corregido (QTc con la morbimortalidad cardiovascular en pacientes con diabetes mellitus tipo 2, se realizó el seguimiento a 5 años de 67 pacientes que acudieron a consulta externa del Servicio de Endocrinología. Se presentaron eventos cardiovasculares en 16 pacientes; el 82% completó el seguimiento y se encontró que el intervalo QTc prolongado fue la única variable que se asoció de forma significativa a morbimortalidad cardiovascular en el análisis de regresión logística múltiple (RR: 13,56; IC 95%: 2,01-91,36 (p=0,0074.In order to evaluate the relationship between cardiovascular autonomic neuropathy and corrected QT interval (QTc with cardiovascular morbidity and mortality in patients with type 2 diabetes mellitus, we followed up for 5 years 67 patients attending the outpatient Endocrinology Service. 82% completed follow-up and cardiovascular events occurred in 16 patients. We found that long QTc interval was the only variable significantly associated with cardiovascular morbidity and mortality in the multiple logistic regression analysis (RR: 13.56, 95% CI: 2.01-91.36 (p = 0.0074.

  13. Causas referidas para o desenvolvimento de úlceras em pés de pessoas com diabetes mellitus Causas referidas al desarrollo de úlceras en piés de personas con diabetes mellitus Root causes for the development of foot ulcers of people with diabetes mellitus

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    Isabela dos Santos Martin

    2012-01-01

    Full Text Available OBJETIVO: Analisar as causas referidas na etiologia das úlceras em pés de pessoas com Diabetes mellitus (DM. MÉTODOS: Estudo seccional, quantitativo, realizado no Ambulatório de Diabetes de um Hospital Universitário em Ribeirão Preto - SP. Os dados foram coletados com instrumento estruturado e exame físico dos pés de amostra de 30 pacientes diabéticos. RESULTADOS: Amostra com idade média de 57,5 anos, predominância do sexo masculino e baixa escolaridade; 90% possuíam DM tipo 2, de longa duração e mal controlado; obesidade/sobrepeso em 77% e insensibilidade plantar em 93,3%. A região metatarsiana foi o local de úlcera referido com maior frequência, e a causa foi a calosidade. CONCLUSÃO: as causas referidas envolvidas na etiologia das úlceras correspondem, de forma direta ou indireta, a fatores extrínsecos que podem ser prevenidos com cuidados básicos e de baixo custo. A insensibilidade plantar, fator fundamental desencadeador das úlceras, no entanto não foi reconhecida pelas pessoas.OBJETIVO: Analizar las causas referidas en la etiología de las úlceras en piés de personas con Diabetes mellitus (DM. MÉTODOS: Estudio seccional, cuantitativo, realizado en el consultorio externo de Diabetes de un Hospital Universitario en Ribeirão Preto - SP. Los datos fueron recolectados con un instrumento estructurado y examen físico de los piés de una muestra de 30 pacientes diabéticos. RESULTADOS: muestra conformada por personas con una edad promedio de 57,5 años, predominio del sexo masculino y baja escolaridad;el 90% poseían DM tipo 2, de larga duración y mal controlado; obesidad/sobre peso en el 77% e insensibilidad plantar en el 93,3%. La región metatarsiana fue referida, con mayor frecuencia, como el lugar de la úlcera y la causa fue la callosidad. CONCLUSIÓN: Las causas que están involucradas en la etiología de las úlceras corresponden, de forma directa o indirecta, a factores extrínsecos que pueden ser prevenidos

  14. Resultados de un seguimiento educativo a personas con diabetes mellitus tipo 2 y sobrepeso u obesidad Results of educational follow-up of persons with type 2 diabetes mellitus and overweight/obesity

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    Rosario García

    2003-12-01

    Full Text Available El presente trabajo muestra los resultados de un seguimiento educativo a personas con diabetes mellitus tipo 2 y sobrepeso corporal u obesidad, realizado como continuidad del estudio latinoamericano PEDNID-LA, con el objetivo de evaluar, en forma prospectiva, los cambios clínicos, bioquímicos y terapéuticos obtenidos después de participar en un programa de educación grupal con metodología interactiva. El estudio incluyó 40 pacientes no insulino dependientes, obesos o en sobrepeso y preferentemente de reciente inicio de la enfermedad, seleccionados en orden cronológico de asistencia a la consulta ambulatoria. Se estableció una consulta interactiva trimestral, donde cuidados y educación se desarrollaban como una unidad, y el contenido educativo iba surgiendo de las necesidades reales y sentidas del grupo, lo que se centró en promover la participación activa del paciente y aumentar la adhesión al tratamiento, con prioridad del plan de alimentación, la actividad física, la reducción del peso corporal y el automonitoreo de glucosa en orina, tal como se había hecho con otros grupos de personas con diabetes. Los conocimientos sobre diabetes se midieron en cuestionarios idénticos diseñados en el protocolo general multicéntrico del estudio PEDNID-LA y aplicados al inicio y final de dicho estudio y a los 4 años del seguimiento interactivo. El resto de las variables fueron valoradas antes, después del año del estudio PEDNID-LA y a los 4 años del seguimiento interactivo. Los datos fueron procesados mediante el uso del programa Epi-Info. Las diferencias estadísticas se determinaron por prueba de Chi cuadrado, y se aceptó p The present paper showed the results of educational follow-up of persons with type 2 diabetes mellitus and overweight/obesity carried out as part of the Latin American study PEDNID-LA, with the objective of prospectively evaluating the clinical, biological and therapeutic changes after their participation in a

  15. Impacto de un servicio de seguimiento farmacoterapéutico implementado a pacientes con diabetes mellitus tipo 2 Impact of a pharmaceutical follow-up service implemented in type 2 diabetes mellitus patients

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    Yaily Lazo Roblejo

    2011-06-01

    Full Text Available Se evaluó el impacto de un servicio de seguimiento farmacoterapéutico implementado a 30 pacientes con diabetes mellitus tipo 2, dispensarizados en la Farmacia Principal Municipal Santiago de Cuba, según la metodología Dáder, en el período comprendido desde enero del 2009 hasta enero de 2010. El índice de impacto de la estabilidad clínica de los pacientes resultó moderado, mientras que en las intervenciones farmacéuticas aceptadas y el nivel de satisfacción de los pacientes, los índices de impacto obtenidos fueron elevados, por lo que el impacto global del servicio de seguimiento farmacoterapéutico implementado para la atención de estos fue considerado alto.The impact of a pharmacotherapy follow-up service was assessed in 30 patients dispensarized in municipal main drugstore of Santiago de Cuba according to Dáder's methodology from January, 2009 to January, 2010. The level of the clinical stability impact of patients was qualified as moderate, whereas in the accepted pharmaceutical interventions and at level of patient's satisfaction, the rates of impact achieved were high thus; the global above mentioned service repercussion was also qualified as high.

  16. Lipoproteína (a está associada com níveis basais de insulina em pacientes com Diabetes Mellitus tipo 2 Lipoproteína (a está asociada a niveles basales de insulina en pacientes con Diabetes Mellitus tipo 2 Lipoprotein (a is associated with basal insulin levels in patients with type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Syed Shahid Habib

    2009-07-01

    Full Text Available FUNDAMENTO: Ainda não foi claramente estabelecido se a resistência/deficiência insulínica leva diretamente à aterogênese ou através de sua associação com outros fatores de risco como os níveis de lipoproteína (a[Lp(a]. OBJETIVO: O objetivo do estudo foi estabelecer a relação entre os níveis basais de insulina, lípides e lipoproteína (a em pacientes com diabetes mellitus (DM tipo 2. MÉTODOS: Amostras de sangue foram colhidas em jejum e os níveis de insulina, lipoproteína (a, colesterol total (CT, triglicérides (TG, lipoproteína de baixa densidade (LDL-C, lipoproteína de alta densidade (LDL-C, glicose e hemoglobina glicada (HbA1c foram medidos em 60 pacientes com DM tipo 2 e 28 indivíduos saudáveis. Nós dividimos os pacientes em dois grupos baseados nos níveis basais de insulina: > 10 µIU/ml e 10 µIU/ml comparados com aqueles que apresentavam insulina basal FUNDAMENTO: Todavía no se aclaró totalmente si la resistencia/deficiencia insulínica lleva directamente a la aterogénesis o a través de su asociación con otros factores de riesgo como los niveles de lipoproteína (a [Lp(a]. OBJETIVO: : El objetivo del estudio fue establecer la relación entre los niveles basales de insulina, lípidos y lipoproteína (a en pacientes con diabetes mellitus (DM tipo 2. MÉTODOS: Se extrajeron muestras de sangre en ayuno y se determinaron los niveles de insulina, lipoproteína (a, colesterol total (CT, triglicéridos (TG, lipoproteína de baja densidad (LDL-C, lipoproteína de alta densidad (LDL-C, glucosa y hemoglobina glicosilada (HbA1c en 60 pacientes con DM tipo 2 y 28 individuos sanos. Dividimos a los pacientes en dos grupos basados en los niveles basales de insulina: > 10 µIU/ml y 10 µIU/ml comparados con aquellos que presentaban insulina basal BACKGROUND: It has not been clearly established whether insulin resistance/deficiency leads directly to atherogenesis or through its association with other risk factors such as

  17. Visão do mundo, cuidado cultural e conceito ambiental: o cuidado do idoso com diabetes Mellitus Visión del cuidado del medio ambiente mundial cultural y concepto: el cuidado diario de la tercera edad con diabetes Mellitus World-view, cultural care and environmental concept: the daily care of the elderly with diabetes Mellitus

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    Nayana Maria Gomes Souza

    2012-03-01

    Full Text Available Este estudo objetivou analisar o cotidiano do cuidado do idoso com Diabetes Mellitus tipo 2 (DM2, segundo os pressupostos teóricos de Leininger. É um estudo descritivo, qualitativo, realizado com oito idosos com DM2 atendidos na atenção básica. As informações foram coletadas por meio de entrevista semi-estruturada, organizadas e discutidas por meio da análise de conteúdo. As categorias que emergiram dos depoimentos, segundo os conceitos de Leininger, foram: Visão do Mundo, Cuidado Cultural e Contexto Ambiental. Entendemos que os idosos com DM2 sentem sua vida sob fragilidade constante, em um mundo de restrições, entretanto, buscam garantir sua saúde através do cultivo à fé com a religiosidade, do uso das plantas medicinais e do apoio dos profissionais de saúde.Este estudio analiza el cuidado de los ancianos con DM de acuerdo a los supuestos teóricos de Leininger. Este es un estudio descriptivo, cualitativo, con la participación de ocho ancianos con diabetes Mellitus en una Unidad de Salud en Fortaleza, Ceará, Brasil. La información fue recogida a través de entrevistas semi-estructuradas, organizadas y discutidos por medio del análisis de contenido. Las categorías que surgieron de los testimonios de acuerdo con los conceptos de Leininger fueron: Visión Mundial, Cuidado Cultural y el Contexto del Medio Ambiente. Creemos que los ancianos con diabetes Mellitus sienten sus vidas bajo la constante amenaza en un mundo de limitaciones, sin embargo, velan por su salud a través del cultivo de la fe en la religión, del uso de plantas medicinales, y con el apoyo de profesionales de la salud.This study aimed to analyze the daily care of the elderly with type 2 diabetes Mellitus (DM2 in the light of the theoretical assumptions of Leininger. This is a descriptive, qualitative study, with the participation of 8 elderly patients with DM2 in a Health Unit in the city of Fortaleza, state of Ceará, Brazil. The data were collected through

  18. General aspects of diabetes mellitus.

    Science.gov (United States)

    Alam, Uazman; Asghar, Omar; Azmi, Shazli; Malik, Rayaz A

    2014-01-01

    Diabetes mellitus is a heterogeneous group of disorders characterized by hyperglycemia due to an absolute or relative deficit in insulin production or action. The chronic hyperglycemia of diabetes mellitus is associated with end organ damage, dysfunction, and failure, including the retina, kidney, nervous system, heart, and blood vessels. The International Diabetes Federation (IDF) estimated an overall prevalence of diabetes mellitus to be 366 million in 2011, and predicted a rise to 552 million by 2030. The treatment of diabetes mellitus is determined by the etiopathology and is most commonly subdivided in type 1 and type 2 diabetes mellitus. There is a greater propensity towards hyperglycemia in individuals with coexisting genetic predisposition or concomitant drug therapy such as corticosteroids. The screening for diabetes mellitus may either be in the form of a 2hour oral glucose tolerance test, or via HbA1c testing, as recently recommended by the American Diabetes Association (ADA). Strong associations have been shown in observational studies suggesting poor clinical outcomes both with chronic hyperglycemia and acutely in intensive care settings. However, tight glycemic control in this setting is a contentious issue with an increased incidence of hypoglycemia and possible increase in morbidity and mortality. In a critically ill patient a glucose range of 140-180mg/dL (7.8-10.0mmol/L) should be maintained via continuous intravenous insulin infusion.

  19. Monocyte functions in diabetes mellitus

    DEFF Research Database (Denmark)

    Geisler, C; Almdal, T; Bennedsen, J

    1982-01-01

    The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from...... for the elucidation of concomitant infections in diabetic patients are discussed....

  20. Screening for gestational diabetes mellitus

    NARCIS (Netherlands)

    van Leeuwen, M.

    2012-01-01

    Gestational diabetes mellitus is associated with increased risk of complications for mother and child. Along with the growing epidemic of obesity and type 2 diabetes, the prevalence of gestational diabetes is expected to rise. With adequate and timely treatment, the risk of complications is reduced.

  1. Intervención psicológica en pacientes con diagnóstico de diabetes mellitus

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    Gina Castro Cabeza

    2013-12-01

    Full Text Available La diabetes es una enfermedad que tiene su origen en una alteración orgánica, sin embargo, y dada la complejidad de la naturaleza humana, existen variables de orden psicológico que intervienen en el desarrollo de la enfermedad, estas dependen de las características y habilidades comportamentales de los pacientes para afrontar la enfermedad. Dado lo anterior es importante educar al paciente para que sea capaz de asumir de forma adaptativa y eficaz el tratamiento con el objetivo de mejorar su calidad de vida. Las estrategias de intervención se construyen a partir de la educación y evaluación de las esferas conductual, cognitiva y emocional del paciente, así mismo, de las habilidades de autocuidado, adherencia al tratamiento y recursos de afrontamiento frente al estrés; con el fin de diseñar propuestas ideográficas de intervención en dichos pacientes.

  2. O significado do ensino por telefone sobre a insulina para pessoas com diabetes Mellitus El significado del enseñanza por teléphono sobre la insulina para personas con diabetes Mellitus The meaning of teaching by telephone on the insulin for patients with diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Camila Aparecida Pinheiro Landim

    2011-09-01

    Full Text Available Objetivou-se identificar o significado do acompanhamento por telefone sobre o processo de preparo e aplicação de insulina para pessoas com diabetes Mellitus (DM. Estudo descritivo, de abordagem qualitativa, com 26 pessoas com DM tipo 2 em uso de insulina, participantes de um programa brasileiro de automonitorização da glicemia capilar no domicílio que emprega o uso do telefone como estratégia de enfermagem. Utilizou-se entrevista dirigida, em único contato telefônico, com questões fundamentadas na Teoria Representacional de Significado de Ogden Richards. O significado obtido conteve aspectos relacionados ao processo ensino-aprendizagem e à ajuda percebida pela estratégia (símbolo, elementos relacionados ao manuseio da insulina (referente e o reconhecimento do acompanhamento por telefone como comodidade, tranquilidade, atenção e tempo para o esclarecimento de dúvidas (pensamento. Considera-se esta estratégia adequada para orientação de pessoas com DM em uso de insulina.Este estudio identificó el significado de seguimiento telefónico en el proceso de preparación y administración de la insulina desde la perspectiva de los pacientes con diabetes Mellitus (DM. Estudio descriptivo con enfoque cualitativo, con 26 pacientes con DM tipo2 em el uso de insulina y participantes en un programa brasileño de autocontrol de glucosa en sangre capilar, en el hogar, que utiliza el seguimiento telefónico como una estratégia de enfermería. Las entrevistas directas se realizaron en un contacto telefónico único, con preguntas basadas en la teoría del significado de Ogden y Richards. El significado se obtuvo en relación con el proceso de enseñanza-aprendizaje y de la ayuda percibida (símbolo, los elementos relacionados con el manejo de la insulina (referente, y un reconocimiento de el seguimiento telefónico ser conveniente, fácil, de atención y tiempo para aclarar dudas (pensamiento. El seguimiento telefónico es conveniente para

  3. Prevalencia de neuropatía autonómica cardiovascular en pacientes con diabetes mellitus tipo 2 de un hospital general.

    Directory of Open Access Journals (Sweden)

    Ray Ticse Aguirre

    2007-07-01

    Full Text Available Objetivo: Determinar la prevalencia de la neuropatía autonómica cardiovascular (NACV en pacientes con diabetes tipo 2, que acuden de manera regular al consultorio del servicio de Endocrinología del Hospital Nacional Cayetano Heredia (HNCH y los factores que se asocian a su presentación. Material y Métodos: Ingresaron 81 pacientes que cumplieron con los criterios de inclusión y exclusión. Se aplicaron cuatro pruebas para el diagnóstico de NACV, según el consenso de San Antonio sobre Neuropatía Diabética: Test de Valsalva, razón 30/15, hipotensión ortostática y variación de la frecuencia cardiaca. Además se tomaron datos demográficos, metabólicos, patológicos y de complicaciones por la diabetes. Se aplicó el test MDNS (Michigan Diabetic Neuropatic Score y electromiografía para el diagnóstico de neuropatía periférica. Se dividió en dos grupos según la presencia o no de NACV y se buscó diferencias. Resultados: El grupo de pacientes con NACV presentó mayor tiempo de enfermedad (10,36 ± 6,88 vs 6,32 ± 6,75; p=0,008, mayores niveles de glicemia en ayunas (160,55 ± 54,78 vs 120,63 ± 43,68; p=0,001 y de hemoglobina glicosilada (10,47 ± 2,06 vs 9,30 ± 2,14; p=0,013. No se halló diferencias significativas en las demás variables. Conclusiones: La frecuencia de de NACV en pacientes con diabetes mellitus tipo 2 del HNCH es de 41,47%. Se asocia a niveles altos de glucosa en ayunas, hemoglobina glicosilada.y mayor tiempo de enfermedad. (Rev Med Hered 2007;18:129-135.

  4. Monogenic diabetes mellitus in Norway

    OpenAIRE

    Oddmund Søvika; Henrik Underthun Irgens; Janne Molnes; Jørn V. Sagena; Lise Bjørkhaug; Helge Ræder; Anders Molveng; Pål R. Njølstad

    2013-01-01

    Here, we review data on monogenic diabetes mellitus in Norway based on the Norwegian MODY Registry at Haukeland University Hospital, Bergen. This registry comprises established or suspected cases of maturity-onset diabetes of the young (MODY) referred to our laboratory for genetic testing. We also present data on neonatal diabetes, another group of monogenic diabetes. To date, we have genetically diagnosed nearly 500 MODY cases in Norway. Mutations in the HNF1A gene (MODY3) were detected in a...

  5. Frecuencia de la hipertensión arterial y su relación con algunas variables clínicas en pacientes con diabetes mellitus tipo 2 High blood pressure frequency and its relation to some clinical variables in patients diagnosed with type 2 diabetes mellitus

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    Eduardo Valdés Ramos

    2009-12-01

    Full Text Available Se realizó un estudio descriptivo transversal con 300 pacientes diabéticos tipo 2 ingresados en el Centro de Atención al Diabético de Bayamo, Granma, en el período comprendido entre octubre de 2007 y mayo de 2008, con el objetivo de conocer la frecuencia de hipertensión arterial y su relación con algunas variables clínicas en estos casos. Se revisaron las historias clínicas de cada uno de ellos para obtener datos de los aspectos siguientes: edad, sexo, color de la piel, hábitos tóxicos, edad al comienzo de la diabetes, estado nutricional, circunferencia de la cintura, tensión arterial y complicaciones crónicas de la diabetes. Se encontró hipertensión arterial en 210 pacientes (70 %; de ellos, 57 (27,1 % presentaron hipertensión sistólica aislada, 39 (18,5 % hipertensión diastólica, y 114 (54,4 % hipertensión sistodiastólica. La hipertensión arterial se presentó desde el inicio de la diabetes en el 62,9 %. El 76,1 % de los pacientes hipertensos tenían sobrepeso u obesidad (P=0,0557. Resultó significativa la asociación entre la hipertensión arterial y la cardiopatía isquémica (p= 0,0117. En relación con el ictus y la insuficiencia arterial periférica, aunque la mayoría de los casos eran hipertensos, no llegó a ser estadísticamente significativo (p= 0,8261, p= 0,8600. El 71,1 % de los pacientes con retinopatía diabética y el 75 % con nefropatía diabética eran hipertensos (p= 0,8261, p= 0,8600. Se concluye que la hipertensión arterial tiene una elevada incidencia en los pacientes con diabetes mellitas tipo 2, porque está presente en un porcentaje importante desde el diagnóstico de la diabetes y se asocia significativamente a la presencia de cardiopatía isquémica.A cross-sectional and descriptive study was conducted in 300 patients with type 2 diabetes admitted in Diabetes Care Center of Bayamo, Granma province between October, 2007 and May, 2008 to know the high blood pressure frequency and its relation to

  6. Tuberculosis en pacientes con diabetes mellitus: Un estudio epidemiológico y clínico en el Hospital Nacional Cayetano Heredia

    Directory of Open Access Journals (Sweden)

    Juan Luis DELGADO ROSPIGLIOSI

    2006-07-01

    Full Text Available Objetivo: Describir las características epidemiológicas y clínicas de pacientes diabéticos con tuberculosis atendidos en el Hospital Nacional Cayetano Heredia (HNCH. Material y Métodos: Estudio retrospectivo, observacional, descriptivo. Se identificaron los "casos" (pacientes diabéticos con TBC revisando los registros del Servicio de Endocrinología, Servicios de hospitalización de Medicina y del Departamento de Enfermedades Infecciosas y Tropicales del HNCH atendidos durante el periodo de 1997 al 2003. Resultados: Se encontraron 85 episodios de TBC en 74 historias clínicas revisadas. El promedio de edad fue de 49,4 +12,8 años; 48/74 (65% fueron hombres y 26/74 (35% mujeres. 72/74 (97,3% pacientes presentaron diabetes mellitus tipo 2. El tiempo promedio de enfermedad diabética previo al desarrollo de TBC fue de 4.2 +4 años. 75/85 (88,2% episodios presentaron TBC pulmonar, habiendo confirmación bacteriológica en el 51,3% de estos casos. 59/85 (69% casos no cumplían regularmente con el tratamiento indicado para la diabetes y 60/85 (71% tenían mal control metabólico al desarrollar TBC. 31/74 (42% pacientes fueron hospitalizados por TBC, asociándose cetoacidosis diabética (CAD en el 51,4% de las hospitalizaciones por esta causa. La TBC puede ser causa importante desencadenante de CAD en nuestro medio. La tasa de fracasos al tratamiento fue de 15/85 (17,6%; hubo sospecha de TB-MDR en 13/74 pacientes (17,6%. La tasa de recaídas fue de 15/74 (20,3%. Fallecieron 3/74 pacientes (4% durante el período de estudio. Conclusiones: Pacientes diabéticos mal controlados desarrollan TBC con una elevada tasa de recaídas, fracasos y TB-MDR, con alta sospecha de contagio intrahospitalario. (Rev Med Hered 2006;17:132-140.

  7. O manejo da cetoacidose em pacientes com Diabetes Mellitus : subsídios para a prática clínica de enfermagem El manejo de la cetoacidosis en pacientes con Diabetes Mellitus:subsidios para la práctica clínica de enfermería Management of diabetic ketoacidosis in Diabetic patients: clinical practice nursing recommendations

    Directory of Open Access Journals (Sweden)

    Sonia Aurora Alves Grossi

    2006-12-01

    Full Text Available A cetoacidose diabética é uma condição aguda e grave que se desenvolve predominantemente em pacientes com Diabetes mellitus do tipo 1 e é induzida pela deficiência relativa ou absoluta de insulina. Ocorre comumente em associação a situações de estresse, que elevam os níveis dos hormônios contra-reguladores e constitui importante emergência clínica, que requer intervenções imediatas e efetivas. Assim, pretende-se, por meio deste artigo, com base na fisiopatologia e nas manifestações clínicas, fornecer subsídios para a prática clínica de enfermagem no manejo da cetoacidose diabética.La cetoacidosis diabética es una condición aguda y grave que se desarrolla predominantemente en los pacientes con Diabetes mellitus del tipo 1 y es inducida por la deficiencia relativa o absoluta de insulina. Ocurre generalmente asociada a situaciones de estrés, que elevan los niveles de las hormonas contra-reguladoras, constituyéndose en una importante emergencia clínica, que requiere intervenciones inmediatas y efectivas. Así, se pretende, por medio de este artículo, con base en la fisiopatología y en las manifestaciones clínicas, ofrecer elementos de juicio para la práctica clínica de enfermería en el manejo de la cetoacidosis diabética.Diabetic ketoacidosis is a severe and acute condition in Type 1 Diabetes mellitus that is prompted by relative or absolute insulin deficiency. It is frequently related to stressful situations, in which stress hormones are elevated. It is considered a clinical emergency that requires immediate and effective intervention. This article, based on the physiopathology and the clinical manifestations, aims at providing clinical practice nursing recommendations for the management of diabetic ketoacidosis.

  8. Diabetes mellitus, maar welk type?

    NARCIS (Netherlands)

    Hoekstra, J. B.; de Koning, E. J.

    2004-01-01

    In three patients with an unusual presentation of diabetes mellitus, the classification of their diabetes was troublesome. An adolescent male with slightly elevated blood-glucose levels turned out to have excellent glycaemic control on sulphonylurea derivatives only. When he was 40 years of age, his

  9. Intervenção educativa para o autocuidado de indíviduos com diabetes mellitus Intervención educativa para el autocuidado de individuos con diabetes mellitus Educational intervention for self-care of individuals with diabetes mellitus

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    Heloisa de Carvalho Torres

    2011-01-01

    Full Text Available OBJETIVO: Analisar conhecimentos, atitudes e práticas do autocuidado de indivíduos com Diabetes mellitus (DM em um serviço especializado de saúde de Belo Horizonte - MG, Brasil. MÉTODOS: Pesquisa do tipo estudo de caso com abordagem qualitativa. Os dados foram coletados por meio da realização de grupos focais com participação de 12 indivíduos com DM e que compareceram em três sessões do programa educativo desenvolvido nesse serviço de saúde. RESULTADOS: Os dados, analisados segundo o enfoque da análise temática, possibilitaram a identificação das seguintes categorias: Experiências; Sentimentos; Prática educativa para o autocuidado, associada à alimentação e à atividade física; Barreiras percebidas para a busca de um estilo de vida saudável; e Expectativas. CONCLUSÃO: Os resultados do estudo mostraram a importância da educação e da comunicação em saúde pautadas nas relações dialógicas e na valorização do saber popular, ao reorientarem as práticas educativas para o autocuidado, de forma a estabelecer estratégias de prevenção e controle da doença.OBJETIVO: Analizar conocimientos, actitudes y prácticas del autocuidado de individuos con Diabetes mellitus (DM en un servicio especializado de salud de Belo Horizonte - MG, Brasil. MÉTODOS: Investigación de tipo estudio de caso con abordaje cualitativo. Los datos fueron recolectados por medio de la realización de grupos focales con la participación de 12 individuos con DM y que asistieron a tres sesiones del programa educativo desarrollado en ese servicio de salud. RESULTADOS: Los datos, analizados según el enfoque del análisis temático, posibilitaron la identificación de las siguientes categorías: Experiencias; Sentimientos; Práctica educativa para el autocuidado, asociada a la alimentación y a la actividad física; Barreras percibidas para la búsqueda de un estilo de vida saludable; y Expectativas. CONCLUSIÓN: Los resultados del estudio mostraron

  10. Women with type 2 diabetes mellitus: sociodemographic profile, biometrics and health Mujeres con Diabetes mellitus tipo 2: perfil sociodemográfico, biométrico y de salud Mulheres com Diabetes mellitus tipo 2: perfil sociodemográfico, biométrico e de saúde

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    Juliana Cristina Lessmann

    2012-01-01

    Full Text Available OBJECTIVE: To understand the profile of women with type 2 diabetes mellitus, focusing on sociodemographic factors, biometrics and health. METHODS: A quantitative, transversal, prospective study with a stratified random sample, conducted in Florianópolis/SC with 147 women by means of home visits between April and August of 2009. RESULTS: The women had a mean age of 66 years, presented elevated indexes of body weight, capillary glycemia and abdominal circumference, along with a low adherence to non-pharmacological treatment. A low educational level was associated with inadequate glycemic control, no physical activity, and inadequacy of the diet. CONCLUSIONS: Women with lower education constitute a vulnerable group and require health interventions congruent with their capacities of understanding and possibilities of adaptation to treatment.OBJETIVO: Conocer el perfil de mujeres con Diabetes mellitus tipo 2, enfocando factores sociodemográficos, biométricos y de salud. MÉTODOS: Estudio de abordaje cuantitativo, transversal, prospectivo realizado con una muestra estratificada aleatoria, desarrollado en Florianópolis/SC con 147 mujeres por medio de visitas domiciliarias entre abril y agosto del 2009. RESULTADOS: Las mujeres tenían edad promedio de 66 años, presentaron elevados índices de masa corporal, glicemia capilar y circunferencia abdominal, además de baja adhesión al tratamiento no medicamentoso. La baja escolaridad se asoció al control inadecuado de la glicemia, no realización de actividad física e inadecuación de la dieta. CONCLUSIONES: Las mujeres con baja escolaridad constituyen un grupo vulnerable y necesitan intervenciones en salud congruentes con sus capacidades de comprensión y posibilidades de adaptación al tratamiento.OBJETIVO: Conhecer o perfil de mulheres com Diabetes mellitus tipo 2, enfocando fatores sociodemográficos, biométricos e de saúde. MÉTODOS: Estudo de abordagem quantitativa, transversal, prospectivo

  11. The perspectives of Brazilian homemakers concerning living with type 2 diabetes mellitus La perspectiva de ama de casa brasileña sobre la vida con diabetes mellitus tipo 2 As perspectivas de donas de casa brasileiras sobre a sua experiência com diabetes mellitus tipo 2

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    Denise Maria Guerreiro Vieira da Silva

    2012-06-01

    Full Text Available The purpose of this study is to present an understanding of the experience of Brazilian homemakers with type 2 diabetes mellitus (DM2. A descriptive exploratory design was used and semi-structured interviews were conducted with 25 Brazilian homemakers concerning their experience. The interviews were recorded, transcribed, and the resulting text was analyzed using the sequential step method. Data converged to one dominant category, "constructing one's identity in the family context", which is comprised of three categories: gender differences; day-to-day concerns; and incongruity between knowledge and behavior related to DM2. These findings suggest that participants construct their identities within the family context and that their experience of living with DM2 is integral to their self-identification as wives and mothers. This, in turn, has implications for the design and implementation of programs to assist women in managing DM2 effectively.El propósito de este estudio es comprender la experiencia de las amas de casa brasileñas con la diabetes mellitus tipo 2 (DM2. Se empleo un abordaje exploratorio descriptivo, donde participaron de las entrevistas 25 amas de casa de Brasil acerca de su experiencia con el DM. Las entrevistas fueron grabadas, transcritas y el texto resultante se analizó mediante el método secuencial de cuatro etapas: aprensión, síntesis, teorización y transferencia. Los datos se reunieron en un tema dominante: "construyendo su identidad en el contexto familiar", que se compone de tres sub-temas: las diferencias de género, las preocupaciones del cotidiano y la incongruencia entre el conocimiento y el comportamiento relacionado con DM2. Estos hallazgos sugieren que los participantes construyen su propia identidad dentro del contexto familiar y que su experiencia de vivir con DM2 es parte integral de su identificación como esposas y madres. Esto, a su vez, tiene implicaciones para el planeamiento e implementación de

  12. Pancreatic adenocarcinoma and diabetes mellitus

    International Nuclear Information System (INIS)

    Novotna, T.

    2015-01-01

    Impaired glucose tolerance or frank diabetes mellitus is known to occur more frequently in patients with pancreatic cancer than in the general population. At the time of the diagnosis of pancreatic cancer, more than 70% of patients taking the glucose tolerance test show diabetes or impaired glucose tolerance (1). Relationship among diabetes mellitus and pancreatic cancer is vague but sure, although neither the nature nor the sequence of the possible cause – effect relationship has been established. The reason for the high frequency of glucose intolerance in patients with pancreatic cancer remains controversial. (author)

  13. Self-Care of Patients with Diabetes Mellitus Cared for at an Emergency Service in Mexico Autocuidado de personas con Diabetes Mellitus atendidas en un servicio de urgencia en México Autocuidado de pessoas com diabetes mellitus atendidas em serviço de urgência no México

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    Irasema Romero Baquedano

    2010-12-01

    Full Text Available This study examines the self-care ability of type 2 diabetes mellitus patients and relates it to sociodemographic and clinical variables. The study included 251 patients who were cared for by an emergency service in Mexico, in 2007. Data were obtained through structured interviews held at participants’ households, through a form, a questionnaire and the Self-Care Ability Scale. Descriptive and correlation statistics were used for data analysis. The results show that 83 (33.5% individuals displayed good self-care ability and 168 (66.5% individuals displayed regular ability. A directly proportional correlation was found between self-care ability and schooling (r=0.124; pEste estudio tuvo por objetivos determinar la capacidad de autocuidado de personas con diabetes mellitus tipo 2 y relacionar esa capacidad con algunas variables sociodemográficas y clínicas. Participaron 251 personas que ingresaron en un hospital de urgencia en México, en 2007. Los datos fueron obtenidos mediante entrevista domiciliar dirigida, utilizándose de formulario, cuestionario y Escala de Capacidad de Autocuidado. Para el análisis se utilizó estadística descriptiva y correlacional. Los resultados mostraron que 83 (33,5% sujetos presentaron buena capacidad de autocuidado y 168 (66,5% capacidad regular. Se obtuvo una correlación directamente proporcional entre capacidad de autocuidado y años de estudio (r=0,124; pEste estudo teve por objetivos determinar a capacidade de autocuidado de pessoas com diabetes mellitus tipo 2 e relacionar esse distúrbio com algumas variáveis sociodemográficas e clínicas. Participaram 251 pessoas que ingressaram em um hospital de urgência no México, em 2007. Os dados foram obtidos mediante entrevista domiciliar dirigida, utilizando-se de formulário, questionário e Escala de Capacidade de Autocuidado. Para a análise, utilizou-se estatística descritiva e correlacional. Os resultados mostraram que 83 (33,5% sujeitos apresentaram

  14. Morbidades e qualidade de vida de idosos com diabetes mellitus residentes nas zonas rural e urbana Morbilidades y calidad de vida de ancianos con diabetes mellitus residentes en zonas rurales y urbanas Morbidity and quality of life of elderly individuals with diabetes mellitus living in urban and rural areas

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    Érica Aparecida dos Santos

    2013-04-01

    Full Text Available Este estudo objetivou descrever as variáveis sociodemográficas e comparar as morbidades e a qualidade de vida (QV dos idosos com diabetes mellitus (DM residentes nas zonas urbana e rural. A amostra foi composta de 271 idosos da zona urbana e 104 da rural que autorreferiram DM. Utilizou-se análise descritiva e, na comparação das localidades, realizou-se ajuste para a idade por meio de regressão logística e linear múltipla (p Se objetivó describir las variables sociodemográficas y comparar morbilidades y calidad de vida (QV de ancianos con diabetes mellitus (DM residentes en zonas urbanas y rurales. Muestra compuesta por 271 ancianos de zona urbana y 104 de zona rural que autorrefirieron padecer DM. Se utilizó análisis descriptivo y, en la comparación de localidades, se efectuó ajuste etario mediante regresión logística y lineal múltiple (pThis study aimed to describe the socio-demographic variables and to compare the morbidities and the quality of life (QoL of elderly individuals with diabetes mellitus (DM residing in urban and rural areas. The sample consisted of 271 elderly individuals from urban areas and 104 from rural areas with self-reported DM. A descriptive analysis was used, and in the location comparison, an age adjustment was employed through linear and logistic multiple regression models (p<0.05. The elderly individuals from the rural area were younger, more educated, earned a higher income and were more often married in relation to the urban residents. Furthermore, the rural residents presented a higher QoL score in the physical and social relationships domains and in the autonomy, past, present and future activities, and intimacy facets compared to the urban residents. The elderly individuals residing in the urban area displayed a larger number of verified comorbidities. The elderly DM patients residing in the rural area generally presented better health conditions than those who lived in the urban area.

  15. DERMATOGLYPHIC PATTERNS IN TYPE 2 DIABETES MELLITUS

    African Journals Online (AJOL)

    2018-02-28

    Feb 28, 2018 ... COMMENTARY. DERMATOGLYPHIC PATTERNS IN TYPE 2 DIABETES. MELLITUS ... contributions in diabetes mellitus and in various medical disorders. Hence dermatoglyphic .... female cases. These findings are similar to ...

  16. Relationship among social support, treatment adherence and metabolic control of diabetes mellitus patients Relación entre apoyo social, adhesión al tratamiento y control metabólico de personas con Diabetes Mellitus Relação entre apoio social, adesão aos tratamentos e controle metabólico de pessoas com diabetes mellitus

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    Lilian Cristiane Gomes-Villas Boas

    2012-02-01

    Full Text Available This cross-sectional and quantitative study aimed to analyze the relationship among social support, adherence to non-pharmacological (diet and physical exercise and pharmacological treatments (insulin and/or oral anti-diabetic medication and clinical and metabolic control of 162 type 2 diabetes mellitus patients. Data were collected through instruments validated for Brazil. Social support was directly correlated with treatment adherence. Adherence to non-pharmacological treatment was inversely correlated with body mass index, and medication adherence was inversely correlated with diastolic blood pressure. There were no associations between social support and clinical and metabolic control variables. Findings indicate that social support can be useful to achieve treatment adherence. Studies with other designs should be developed to broaden the analysis of relations between social support and other variables.El presente estudio objetivó analizar la relación entre apoyo social, adhesión a los tratamientos no medicamentoso (dieta y ejercicio físico y medicamentoso(insulina y/o antidiabéticos orales y control clínico-metabólico de 162 personas con diabetes mellitus tipo 2. Se trata de un estudio seccional, de abordaje cuantitativo. Los datos fueron recolectados por medio de instrumentos validados. El apoyo social tuvo correlación directa con la adhesión al tratamiento. Se observó correlación inversa entre adhesión al tratamiento no medicamentoso y índice de masa corporal, así como entre adhesión medicamentosa y presión arterial diastólica. No hubo asociaciones entre apoyo social y variables de control clínico-metabólico. Se concluye que el apoyo social podrá ser útil para obtener la adhesión a los tratamientos. Estudios con otros delineamientos deben ser desarrollados, a fin de ampliar el análisis de las relaciones entre apoyo social y otras variables.O presente estudo objetivou analisar a relação entre apoio social, ades

  17. Perception of social support by individuals with diabetes mellitus and foot ulcers Percepción del apoyo social de la persona con Diabetes mellitus y úlceras en los piés Percepção do apoio social pela pessoa com Diabetes mellitus e úlceras nos pés

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    Ana Laura Galhardo Figueira

    2012-01-01

    Full Text Available OBJECTIVE: To evaluate the perception of social support and the relationship of sociodemographic, clinical and metabolic control variables in individuals with diabetes mellitus and foot ulcers in an outpatient unit. METHODS: A quantitative cross-sectional approach was carried out using a social support network inventory. RESULTS: Participants had a high perception of social support; family and health professionals were identified as the main support sources. Fasting plasma glucose values were directly related with social support. CONCLUSION: Family members were identified as the main support source, which emphasizes their importance in the health care process.OBJETIVO: Evaluar el apoyo social percibido y su relación con las variables sociodemográficas, clínicas y de control metabólico de personas con Diabetes mellitus y úlceras en los piés, con seguimiento ambulatorio. MÉTODOS: Estudio de abordaje cuantitativo, seccional, realizado por medio del Inventario de la Red de Soporte Social. RESULTADOS: Hubo una elevada percepción de apoyo social en la muestra estudiada, siendo las principales fuentes de apoyo los familiares y los profesionales de la salud. En el estudio de la relación entre el AS y las variables sociodemográficas, clínicas y de tratamiento, no hubo correlaciones estadísticamente significativas. En cuanto a las variables de control metabólico, el valor de la glicemia plasmática en ayuno presentó relación directa con el apoyo social. CONCLUSIÓN: La familia fue la fuente de apoyo más señalada, reiterando su importancia en el proceso del cuidado a la salud.OBJETIVO: Avaliar o apoio social percebido e sua relação com as variáveis sociodemográficas, clínicas e de controle metabólico em pessoas com Diabetes mellitus e úlceras nos pés, em seguimento ambulatorial. MÉTODOS: Estudo de abordagem quantitativa, seccional, realizado por meio do Inventário da Rede de Suporte Social. RESULTADOS: Houve elevada percep

  18. Alteraciones de la maduración ósea y el crecimiento en niños con diabetes mellitus insulino dependiente

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    Amarilys Patricia Puig Escobar

    2001-04-01

    Full Text Available Se realizó un estudio retrospectivo de tipo analítico, en el Hospital Docente Pediátrico del Cerro, en un período de 10 años, del 15 de enero de 1989 al 15 de enero de 1999, con el objetivo de identificar el comportamiento de las alteraciones en la maduración ósea y el crecimiento en niños con diabetes mellitus insulinodependiente, y determinar la relación entre los factores seleccionados. El universo estuvo conformado por todos los niños diabéticos insulinodependientes atendidos en el servicio, quedando constituida la muestra por 45 pacientes. Las variables seleccionadas fueron: edad al inicio de la enfermedad, tiempo de evolución, esquema terapéutico, dosis de insulina, y control metabólico. Se detectó que el 82,2 % de lo niños estudiados no presentaron ninguna afectación, mientras que el 15,6 % presentó afectación en la maduración y el 2,2 % en la maduración y el crecimiento. No se diagnosticó ningún caso con afectación solamente en el crecimiento. Las variables que mostraron relación fueron la edad de inicio de la enfermedad menor de 5 años, tiempo de evolución de más de 10 años, esquemas inadecuados, dosis de insulina insuficiente y mal control metabólico. El comportamiento de las alteraciones en la maduración ósea y el crecimiento fueron poco frecuentes, coincidiendo con los datos de la literatura revisada, que incluye a estas complicaciones como excepcionales.The authors made a retrospective and analytical study in the Children Teaching Hospital of Cerro Municipality, from January 15, 1989, to January 15, 1999, to identify the behaviour of the alterations in bone maturation and growth in insulin-dependent diabetes mellitus children, and to determine the relation among the selected factors. The group was composed of all insulin-dependent sick children seen in our service. The sample included 45 patients. The selected variables were: age at onset of the disease, evolution time, therapeutical scheme, insulin

  19. Correlación entre los niveles de Hemoglobina Glicada y las enzimas antioxidantes, en pacientes con Diabetes Mellitus Tipo 2

    OpenAIRE

    Vergaray, L.; Robles, Y.; Flores, E.; Suárez, S.

    2014-01-01

    It has been determined Glycated A1c haemoglobin, Superóxido Dismutase, Glutation peroxidase and Malondialdehide levels in 25 patients with Diabetes mellitus type 2, whom participate in the Education Program for Diabetic Patients, from Arzobispo Loayza Hospital, they were confront with 15 persons apparently healthful control group. There is a positive correlation between Glycated A1c haemoglobin - Superoxido Dismutase (r=0,164, p

  20. duration diabetes mellitus

    African Journals Online (AJOL)

    ... group, type of diabetes, age of onset and duration of diabetes), presence of retinopathy, markers of nephropathy and biochemical variables. ... type 2 diabetes and for each ethnic group. Results. ... time of diabetes diagnosis in blacks than Indians. In the type ... countries, minority groups and disadvantaged communities in.

  1. Percepción de los Beneficios de la Tenencia de Animales de Compañía para las Personas de la Mediana Edad con Diabetes Mellitus Tipo 2

    OpenAIRE

    Hugues H., Beatriz; Álvarez Á., Aimee M.; Castelo E., Lizet; Ledón L., Loraine; Mendoza T., Madelín; Domínguez A., Emma

    2016-01-01

    Se efectuó un estudio con el objetivo de explorar la percepción de personas de la mediana edad con Diabetes Mellitus Tipo 2 (DM2) respecto a la tenencia de animales de compañía y su relación con la satisfacción personal, beneficios sobre la salud psicoemocional, el control metabólico y la motivación para la realización de actividades físicas. El estudio fue de tipo transversal, descriptivo, con 85 personas de 40 a 59 años de edad con DM2 y residentes en La Habana, Cuba. Se confeccionó un cues...

  2. Diabetes mellitus type 1

    OpenAIRE

    Desta, Semere Tekeste

    2017-01-01

    Høgskulen på Vestlandet Avdeling for helsefag for sykepleiere Tittel: Diabetes type 1 Bakgrunn for val av tema: I 2000 var det ca. 130 000 personer i Norge med diabetes, av disse hadde ca. 20 000 diabetes type 1. I dag er det ca. 230 000 personer som har diabetes i Norge. Av disse ca. 28 000 type 1 diabetes. Tallet viser hvor alvorlig sykdommen er, fordi det har vært og fortsatt er, en økning av antall diabetikere i Norge. Type 1 diabetes kan komme i alle aldersgrupper, men vanligvis...

  3. Niveles de GLP-1 tras el test de sobrecarga oral de glucosa en mujeres con antecedentes de diabetes mellitus gestacional

    OpenAIRE

    Maraver Selfa, Silvia María

    2017-01-01

    Se ha descrito una reducción significativa del efecto incretina en pacientes con DM2 que puede deberse a la secreción alterada de las hormonas incretinas y/o a una acción insulinotrópica defectuosa de las mismas. Podría plantearse que este efecto incretina deteriorado en pacientes con trastornos del metabolismo hidrocarbonado, fuese un defecto primario precoz que preceda al desarrollo de la DM2, o secundario a la propia hiperglucemia. Objetivos. Estudiar el patrón de secreción de GLP-1 ...

  4. Teenage pregnancy in type 1 diabetes mellitus.

    Science.gov (United States)

    Carmody, David; Doyle, Aoife; Firth, Richard G R; Byrne, Maria M; Daly, Sean; Mc Auliffe, Fionnuala; Foley, Micheal; Coulter-Smith, Samuel; Kinsley, Brendan T

    2010-03-01

    Younger maternal age at delivery has been linked to adverse reproductive outcomes. Pregnancy complicated by type 1 diabetes mellitus (T1DM) is also associated with adverse pregnancy outcomes. Optimising diabetic glycaemic control prior to pregnancy is known to reduce the rate of congenital abnormalities and improve pregnancy outcomes. Teenage pregnancies are not usually planned and little data exist on teenage pregnancy complicated by T1DM. We sought to identify the glycemic control achieved in teenage pregnancy with T1DM and to clarify if there is an associated increase in adverse pregnancy outcomes compared to those seen in older women with T1DM. We compared outcomes in 18 teenagers (TG) with 582 older women with T1DM (CON) from 1995-2007. TG booked to the combined diabetes-obstetrical service at a median gestational age of 11 weeks (range 6-22) compared to 7 weeks in CON (range 4-40, p teenage women with T1DM book later to specialised care and have worse glycaemic control in pregnancy compared to older women with T1DM. This group also appear to be more insulin resistant than older women in early pregnancy. Our data would suggest that teenagers with type 1 diabetes mellitus may constitute a high-risk group for adverse pregnancy outcomes.

  5. Gestational diabetes mellitus in Greenland

    DEFF Research Database (Denmark)

    Pedersen, Michael Lynge; Olesen, Jesper; Jørgensen, M. E.

    2016-01-01

    Background. Within the last 20 years, the prevalence of gestational diabetes mellitus (GDM) has been reported to be increasing worldwide in correlation with ethnic and geographic variations. The actual prevalence of GDM throughout all of Greenland remains unknown. Objective. The aim of this study...

  6. Glukagonomsyndrom uden diabetes mellitus

    DEFF Research Database (Denmark)

    Mikkelsen, Carsten Sauer; Mikkelsen, Dorthe Bisgaard; Vestergaard, Vibeke

    2008-01-01

    without diabetes. Glucagonoma syndrome is characterized by glucagon overproduction, diabetes, depression, deep venous thrombosis and necrolytic migrating erythema. Glucagonoma is frequently diagnosed late which increases the risk of metastases. It is important not to rule out glucagonoma in patients...... with a relevant clinical picture but without diabetes. Udgivelsesdato: 2008-Nov-17...

  7. Undiagnosed diabetes mellitus and associated factors among ...

    African Journals Online (AJOL)

    Background: Undiagnosed diabetes mellitus cases are at higher risk for diabetic related complications. In low-income African countries, patients with undiagnosed diabetes mellitus account for 75% of diabetes cases. Psychiatric disorders have a greater impact on the global burden of diseases and disability associated with ...

  8. Efecto de la intervención con metformina durante el embarazo en la diabetes mellitus gestacional en mujeres con síndrome de ovario poliquístico: una revisión sistemática y metanálisis

    OpenAIRE

    Viguera Torrealba,Sebastián; Carvajal,Jorge A

    2014-01-01

    La metformina es un sensibilizador a insulina y es efectiva en el tratamiento de la diabetes mellitus tipo 2. Sin embargo, no se ha evaluado las consecuencias funcionales de la administración de metformina durante el embarazo en la diabetes mellitus gestacional (DMG) en mujeres con síndrome de ovario poliquístico (SOP). Para eso efectuamos una revisión sistemática y un metanálisis para determinar el efecto de la metformina sobre la DMG en el SOP. El meta-análisis se realizó en los estudios pu...

  9. Diabetes Mellitus and Heart Failure.

    Science.gov (United States)

    Lehrke, Michael; Marx, Nikolaus

    2017-06-01

    Epidemiologic and clinical data from the last 2 decades have shown that the prevalence of heart failure in diabetes is very high, and the prognosis for patients with heart failure is worse in those with diabetes than in those without diabetes. Experimental data suggest that various mechanisms contribute to the impairment in systolic and diastolic function in patients with diabetes, and there is an increased recognition that these patients develop heart failure independent of the presence of coronary artery disease or its associated risk factors. In addition, current clinical data demonstrated that treatment with the sodium glucose cotransporter 2 inhibitor empagliflozin reduced hospitalization for heart failure in patients with type 2 diabetes mellitus and high cardiovascular risk. This review article summarizes recent data on the prevalence, prognosis, pathophysiology, and therapeutic strategies to treat patients with diabetes and heart failure. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  10. Frecuencia y características clínicas de la retinopatía diabética en un grupo de personas con diabetes mellitus tipo 2 de diagnóstico reciente Frequency and clinical characteristics of diabetic retinopathy in a group of persons recently diagnosed with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Manuel E. Licea Puig

    2003-08-01

    Full Text Available En los últimos años se le ha dedicado mayor atención a la presencia de complicaciones microangiopáticas en las personas con diabetes mellitus tipo 2 (DM 2, y la retinopatía diabética (RD no es una excepción. El objetivo de este trabajo es determinar la frecuencia y las características clínicas de la RD en un grupo de personas con DM 2 de diagnóstico reciente. Se estudiaron 110 pacientes (£ 6 meses con anticuerpos antiislotes pancreáticos (ICA y anti-descarboxilasa del ácido glutámico (AGAD negativos, atendidos consecutivamente en el Centro de Atención al Diabético (CAD, del Instituto Nacional de Endocrinología (INEN, y las variables utilizadas fueron: edad, sexo, hábito de fumar, índice de masa corporal (IMC, edad de debut de la DM 2, presencia de RD y de nefropatía diabética incipiente (NDI, así como la presión arterial. Se determinó ICA, AGAD, hemoglobina glucosilada (HbA1, glucemia en ayunas y posprandial 2 horas después del desayuno y 2 horas después del almuerzo y excreción urinaria de albúmina (EUA en orina de 24 horas. No se incluyó a pacientes con ND diabética clínica (EUA ³ 300 mg/L, ni con otras causas o condiciones de aumento de EUA. Se dividieron en 2 grupos atendiendo a la presencia o no de RD, así como a su severidad y fueron utilizados los criterios propuestos por L'Esperance. El 7 % de la totalidad de la serie presentó algún tipo de RD (7 no proliferativas y 1 proliferativa. La presión arterial sistólica fue de 127,84 ± 19,43 mmHg en aquellos sin RD y de 140 ± 15,27 mmHg , en los que presentaron RDNP (p 20 a In the last few years, great attention has been paid to microangiopathic complications occurred in persons with type 2 diabetes mellitus, and diabetic retinopathy is not the exception. The objective of this paper is to determine the frequency and the clinical characteristics of diabetic retinopathy in a group of persons recently diagnosed with type 2 diabetes mellitus. One hundred ten

  11. Disfunción endotelial y diabetes mellitus Endothelial dysfunction and diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Jeddú Cruz Hernández

    2012-08-01

    Full Text Available Introducción: la disfunción endotelial se presenta con frecuencia en los individuos con diabetes mellitus, debido a que las alteraciones vasculares que aparecen en esta enfermedad y que son provocadas por la hiperglucemia crónica, facilitan su aparición, a lo cual puede contribuir también la hipertensión arterial y la dislipidemia que se presentan en los diabéticos. Objetivo: describir algunos eventos implicados en la aparición de la disfunción endotelial en la diabetes mellitus, y aspectos relacionados con su diagnóstico y tratamiento. Desarrollo: entre los marcadores más importantes de disfunción endotelial en la diabetes mellitus se encuentran, la elevación de las moléculas de adhesión celular y de marcadores de inflamación, la microalbuminuria, la hiperhomocisteinemia, y el incremento de la hemoglobina glucosilada, de la endotelina-1 y del estrés oxidativo. Para el diagnóstico de disfunción endotelial se utilizan la medición de sustancias reguladoras de biofunciones sintetizadas por el endotelio y de otras reconocidas como marcadores de disfunción endotelial, y pruebas indirectas, algunas de las cuales son invasivas; y para su tratamiento, disímiles medidas terapéuticas medicamentosas o no. Conclusiones: es importante identificar la disfunción endotelial tempranamente en los diabéticos y tratarla, en caso de estar presente.Introduction: endothelial dysfunction frequently appears in individuals with diabetes mellitus, because vascular alterations derived from chronic hyperglycemia facilitate the occurrence of the disease, to which blood hypertension and dislipidemia of diabetics also contribute. Objective: to describe some events involved in the onset of endothelial dysfunction in diabetes mellitus and several aspects related to diagnosis and treatment. Development: among the most important markers of endothelial dysfunction in diabetes mellitus are the rises of cell adhesion molecules and inflammation markers

  12. Foot disorders in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Alla Y. Tokmakova

    2017-06-01

    Full Text Available Diabetes mellitus is one of the most common chronic diseases in the world. According to the International Diabetes Federation (IDF, by 2035 the number of diabetes patients will reach 592 million people. Various disorders of the structure and function of the soft tissues and skeleton of the lower extremities is the most common reason that patients seek medical care. The paper presents the modern concept of the pathogenesis, diagnosis, therapeutic and prevention tactics used in the specialized endocrinological and surgical clinics.

  13. Diabetes Mellitus in Peru.

    Science.gov (United States)

    Villena, Jaime E

    2015-01-01

    Peru is an upper medium-income developing country with an increasing prevalence of chronic diseases, including diabetes. To review and describe the epidemiology, drivers, and diabetes care plan in Peru. The medical literature was reviewed based on systematic searching of PubMed, Scielo, and various gray literature from the International Diabetes Federation, World Health Organization, and local Peruvian agencies. In Peru, diabetes affects 7% of the population. Type 2 diabetes accounts for 96.8% of outpatients visits with this condition. Type 1 diabetes has an incidence of 0.4/100,000 per year, and gestational diabetes affects 16% of pregnancies. The prevalence of glucose intolerance is 8.11% and that of impaired fasting glucose 22.4%. The prevalence of overweight, obesity, and metabolic syndrome in adults is 34.7%, 17.5%, and 25%, respectively. Metabolic syndrome prevalence is greater in women and the elderly and at urban and low-altitude locations. Diabetes is the eighth cause of death, the sixth cause of blindness, and the leading cause of end-stage kidney disease and nontraumatic lower limb amputation. In Peru, diabetes accounts for 31.5% of acute myocardial infarctions and 25% of strokes. Infections, diabetic emergencies, and cardiovascular disorders are the main causes for admissions, with a mortality rate Diabetes is a major health care issue in Peru that exposes difficult challenges and shortcomings. The national strategy for tackling diabetes includes promotion of healthy lifestyles; training primary care physicians and providing them with evidence-based clinical practice guidelines, safe and effective medications, and tools for monitoring treatment; and, finally, construction of a comprehensive health care network for early referral in order to prevent, detect, and treat diabetic complications. Copyright © 2015 The Author. Published by Elsevier Inc. All rights reserved.

  14. ESTILO DE VIDA Y ADHERENCIA AL TRATAMIENTO DE LA POBLACIÓN CANARIA CON DIABETES MELLITUS TIPO 2

    OpenAIRE

    Antonio Cabrera de León; José Carlos del Castillo Rodríguez; Santiago Domínguez Coello; María del Cristo Rodríguez Pérez; Buenaventura Brito Díaz; Carlos Borges Álamo; Lourdes Carrillo Fernández; Delia Almeida González; José Juan Alemán Sánchez; Ana González Hernández; Armando Aguirre-Jaime

    2009-01-01

    Fundamento: la población canaria sufre la mayor mortalidad por diabetes tipo 2 (DM2) en España. El objetivo de este estudio es conocer el estilo de vida de las personas diabéticas del archipiélago y su adherencia al tratamiento, así como la DM2 desconocida. Métodos: estudio transversal de 6.729 personas de la población general participantes en la cohorte "CDC de Canarias" (edad 18-75 años). Se obtuvieron sus antecedentes médicos, dieta, actividad física, medicamentos consumidos, tabaco, etc. ...

  15. Diabetes mellitus type 1

    OpenAIRE

    Tøraasen, Lisa Vangen; Al-Sultan, Zainab

    2014-01-01

    Bacheloroppgave i sykepleie, 2014 Hvert år blir rundt 600 nordmenn diagnostisert med sykdommen diabetes type 1, og Norge er et av landene i verden med størst andel av barnediabetes. I dag er det 15 000- 20 000 personer i Norge som har diabetes type 1, og antall barn som får diabetes har fordoblet seg de siste 30 årene (Diabetesforbundet, 2014). Problemstillingen vår gikk ut på hvordan sykepleiere kan veilede og undervise ungdom med nyoppdaget diabetes type på sykehus. Ut i fra litteraturst...

  16. Diabetes mellitus type 1

    OpenAIRE

    Tøraasen, Lisa Vangen; Al-Sultan, Zainab

    2014-01-01

    Hvert år blir rundt 600 nordmenn diagnostisert med sykdommen diabetes type 1, og Norge er et av landene i verden med størst andel av barnediabetes. I dag er det 15 000- 20 000 personer i Norge som har diabetes type 1, og antall barn som får diabetes har fordoblet seg de siste 30 årene (Diabetesforbundet, 2014). Problemstillingen vår gikk ut på hvordan sykepleiere kan veilede og undervise ungdom med nyoppdaget diabetes type på sykehus. Ut i fra litteraturstudiet har vi arbeidet oss frem for å ...

  17. Teenage pregnancy in type 1 diabetes mellitus.

    LENUS (Irish Health Repository)

    Carmody, David

    2010-03-01

    Younger maternal age at delivery has been linked to adverse reproductive outcomes. Pregnancy complicated by type 1 diabetes mellitus (T1DM) is also associated with adverse pregnancy outcomes. Optimising diabetic glycaemic control prior to pregnancy is known to reduce the rate of congenital abnormalities and improve pregnancy outcomes. Teenage pregnancies are not usually planned and little data exist on teenage pregnancy complicated by T1DM. We sought to identify the glycemic control achieved in teenage pregnancy with T1DM and to clarify if there is an associated increase in adverse pregnancy outcomes compared to those seen in older women with T1DM. We compared outcomes in 18 teenagers (TG) with 582 older women with T1DM (CON) from 1995-2007. TG booked to the combined diabetes-obstetrical service at a median gestational age of 11 weeks (range 6-22) compared to 7 weeks in CON (range 4-40, p < 0.02). Glycaemic was worse in TG compared to CON at 13, 26 and 35 weeks gestation, despite higher insulin doses. First trimester miscarriage rate did not differ between groups. Major congenital anomaly rate was 6.2% (1\\/16) compared to 3.2% in CON. This preliminary study has demonstrated that pregnant teenage women with T1DM book later to specialised care and have worse glycaemic control in pregnancy compared to older women with T1DM. This group also appear to be more insulin resistant than older women in early pregnancy. Our data would suggest that teenagers with type 1 diabetes mellitus may constitute a high-risk group for adverse pregnancy outcomes.

  18. Physical activity and diabetes mellitus.

    Science.gov (United States)

    Bhaskarabhatla, Krishna V; Birrer, Richard

    2005-01-01

    Diabetes mellitus (DM), a metabolic syndrome consisting of two main groups, type 1 and 2, is characterized by absolute or relative insulin deficiency or insulin resistance. Individuals with DM take part in physical activity for health promotion, disease management, and or recreational or competitive sports. Several studies confirm the beneficial role of physical activity in favorably altering the prognosis of DM. Exercise as a therapeutic strategy has potential risks, too. Hence, sports medicine physicians caring for athletes with diabetes have several important responsibilities. Diabetic education; pre-participatory evaluation for vascular, neurological, retinal or joint disease; diabetic status and control; promotion of blood glucose self-monitoring; and individualized dietary, medication, and physical activity plans are essential to achieve safe and enjoyable outcomes in individuals with diabetes who are embarking on physical activity.

  19. Evaluación de la atención a personas con diabetes mellitus en una unidad básica de salud

    OpenAIRE

    Silva, Adriana Serafim Bispo e; Santos, Manoel Antônio dos; Teixeira, Carla Regina de Souza; Damasceno, Marta Maria Coelho; Camilo, Josana; Zanetti, Maria Lúcia

    2011-01-01

    Estudo quantitativo transversal com objetivo de avaliar os componentes estrutura e processo na atenção ao usuário com Diabetes Mellitus em uma Unidade Básica Distrital de Saúde do município de Ribeirão Preto-SP. Foram analisados 138 prontuários de usuários com Diabetes Mellitus, em 2008. Como referencial metodológico, utilizou-se a Avaliação de Cuidados em Saúde tendo como recorte a estrutura e o processo. Um formulário contendo 24 questões fechadas foi empregado para a coleta de dados. Em re...

  20. Complicaciones cronicas de la diabetes mellitus

    OpenAIRE

    Isla Pera, Ma. Pilar (María Pilar)

    2012-01-01

    La diabetes mellitus (DM) es una de las enfermedades con mayor impacto sociosanitario, no sólo por su elevada prevalencia, sino, sobre todo, por las consecuencias de las complicaciones crónicas que genera. La hiperglucemia ocasiona daño tanto en el ámbito de la microcirculación como en los grandes vasos provocando lesiones macroangiopáticas y microangiopáticas. Las complicaciones macroangiopáticas se originan a partir de alteraciones o lesiones en los grandes vasos arteriales siendo las más i...

  1. Control metabólico de los adultos mayores con padecimientos de diabetes mellitus e hipertensión arterial Controle metabólico dos adultos maiores que sofrem de diabetes mellitus e hipertensáo arterial Metabolic control of elders with diabetes mellitus and hypertension

    Directory of Open Access Journals (Sweden)

    María Guadalupe Esmeralda Vázquez Treviño

    2011-07-01

    Full Text Available Objetivo: evaluar el comportamiento metabólico asociado a diabetes mellitus e hipertensión arterial durante la aplicación de un programa de atención para el mejoramiento de la calidad nutricional y física en el adulto mayor. Metodología: estudio de carácter comparativo; se trabajó con 20 adultos mayores seleccionados por el criterio de con­veniencia. Los datos se recabaron empleando un cuestionario estructurado que valoró los aspectos físicos y nutricionales. Al mismo tiempo se empleó un registro para llevar el control de los datos antropométricos, de hipertensión arterial, de glicemia capilar y del perfil de lípidos durante la aplicación del programa. Resultados: la población estudiada presentó una edad promedio de 69,17 años, con predominio del género femenino (95%. Durante la implementación del programa, se observa un mejoramiento notorio en cuanto a peso y glicemia capilar se re­fiere; estabilidad en lo que respecta a los niveles de colesterol (9,74% de mejoría y triglicéridos (7,47% de mejoría, mientras que los valores de hipertensión arterial y glicemia no muestran una variación significativa. También se observan cambios lige­ros en cuanto al índice de masa corporal (IMC (0,28 + 0,882, que reflejan una evolución favorable en cuanto a la calidad de vida del adulto mayor, corroborada con la prueba de Wilcoxon (0,027. Conclusión: el comportamiento metabólico del adulto mayor diabético e hipertenso reflejó un comportamiento de mejoría con la implementación de un plan de cuidados adecua­do. Dicho plan muestra un 77% de efectividad con relación a la duración del programa, que a la vez se ve reflejado en el com­portamiento gráfico de los datos.Objetivo: Avaliar o comportamiento metabólico associado á diabete e a hipertensao arterial durante a aplicação de um programa de atencao para o melhoramento da qualidade nutricional e física do adulto maior. Metodologia: Estudo comparativo em que participaram

  2. ESTILO DE VIDA Y ADHERENCIA AL TRATAMIENTO DE LA POBLACIÓN CANARIA CON DIABETES MELLITUS TIPO 2

    Directory of Open Access Journals (Sweden)

    Antonio Cabrera de León

    2009-01-01

    Full Text Available Fundamento: la población canaria sufre la mayor mortalidad por diabetes tipo 2 (DM2 en España. El objetivo de este estudio es conocer el estilo de vida de las personas diabéticas del archipiélago y su adherencia al tratamiento, así como la DM2 desconocida. Métodos: estudio transversal de 6.729 personas de la población general participantes en la cohorte "CDC de Canarias" (edad 18-75 años. Se obtuvieron sus antecedentes médicos, dieta, actividad física, medicamentos consumidos, tabaco, etc. Resultados: la prevalencia de DM2 fue 12% en varones y 10% en mujeres (p=0,005. El 22%de varones y 9% de mujeres desconocían su enfermedad (p<0,001. Sumando DM2 desconocida, DM2 no tratada e incumplimiento terapéutico, el 48% de los hombres y 28% en mujeres no seguían tratamiento correcto. Los varones diabéticos eran más obesos que los no diabéticos (45 versus 25%; p<0,001 pero no presentaban diferencias en tabaquismo (28%; IC95%=23-33 o sedentarismo (62%; IC95%=56-68. Las mujeres diabéticas también eran más obesas (54 versus 27%; p<0,001 y, aunque fumaban menos (11 versus 22%; p<0,001, eran igual de sedentarias (75%; IC95%=70-79. La ingesta calórica era menor en quienes sufrían DM2 (p<0,001, pero el 93% (IC95%=91-95 superaba el consumo recomendado de grasas saturadas y el 69% (IC95%=65-72 padecía síndrome metabólico. Conclusiones: la población diabética en Canarias es sedentaria y obesa, muestra un consumo alto de grasas saturadas y gran prevalencia de síndrome metabólico. El porcentaje que sigue tratamiento regular es muy bajo, sobretodo en varones, que además mantienen el tabaquismo.

  3. Ocular complications of diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    Nihat Sayin; Necip Kara; Gokhan Pekel

    2015-01-01

    Diabetes mellitus (DM) is a important health problemthat induces ernestful complications and it causessignificant morbidity owing to specific microvascularcomplications such as, retinopathy, nephropathy andneuropathy, and macrovascular complications such as,ischaemic heart disease, and peripheral vasculopathy.It can affect children, young people and adults and isbecoming more common. Ocular complications associatedwith DM are progressive and rapidly becoming theworld's most significant cause of morbidity and arepreventable with early detection and timely treatment.This review provides an overview of five main ocularcomplications associated with DM, diabetic retinopathyand papillopathy, cataract, glaucoma, and ocular surfacediseases.

  4. Diabetes mellitus and oral health

    Directory of Open Access Journals (Sweden)

    Đorđević N.

    2015-01-01

    Full Text Available Diabetes mellitus is one of the most common non-communicable chronic diseases, which is the combined action of genetic factors, environmental factors and lifestyle. Specific conditions occur in the oral cavity in the course of diabetes that cause changes in all oral tissues with different symptoms and signs. Increased salivary glucose level is followed by increased accumulation of dental plaque and decreased resistance to noxious agents. The most common oral manifestations in diabetic patients include higher prevalence of periodontal desease, burning mouth syndrome, disruption in salivary flow, opportunistic infections, higher prevalence of denture stomatitis, oral lichen planus, fissured tongue, angular cheilitis etc. Dental interventions in patients with well-controlled diabetes are not different from those applied to nondiabetic patients. Regular monitoring of these patients is required because of the complications that can occur.

  5. Comparative Healthcare: Diabetes Mellitus.

    Directory of Open Access Journals (Sweden)

    Dr Mohammed Ali

    2009-05-01

    Full Text Available In the third in this series of ‘comparative healthcare’ medical practitioners explore the approach to diabetes inBangaldesh and Australia respectively. The social and medical consequences of this chronic conditionare highlighted through the approach to patients at various stages of the disease from two nationalperspectives. An astonishing 7% of the 153 million people are reported to have diabetes in Bangladesh. Manyremain undiagnosed. Delays in diagnosis or management of diabetes have life limiting consequences for thosewho can ill afford private health care in the poorer nation. Screening and early intervention appear to bedenied to many in the developing country. The context is very different with Australians very fortunate to havea coordinated primary health care sector. The outlook for Bangladeshis with uncontrolled diabetes or withtreatable sequela would be unacceptable in Australia. At every stage in the disease trajectory the doctorsemphasise the importance of life style modification, a particular challenge in affluent Australia with its growingincidence of life style related pre morbid conditions in an increasingly sedentary population. A corner stone ofthe support of people with diabetes is the role of nurses and allied health professionals. With a fundedcommitment to multidisciplinary care in the community people with diabetes in Australia have access tosupport closer to home whereas those in Bangladesh remain heavily dependent on specialist, hospital basedservices. One can only speculate how Bangladesh will cope as its population ages and there are an everincreasing proportion of people who require urgent and expensive medical interventions. At the very leastthere is a strong case for greater investment in primary care especially to limit the economic consequences ofdiabetes and other chronic conditions. Finally as in other articles in this series we would like to emphasise that,the views expressed are those of the authors and do

  6. Autoimmune Hypoglycemia in Type 1 Diabetes Mellitus.

    Science.gov (United States)

    Ambigapathy, Jayakumar; Sahoo, Jayaprakash; Kamalanathan, Sadishkumar

    2017-07-15

    Antibodies against exogenous insulin are common in type 1 diabetes mellitus patients. They can cause hypoglycemia, albeit uncommonly. A 14-year-old girl with type 1 diabetes mellitus presented with recurrent hypoglycemia. High insulin, low C-peptide and raised insulin antibody levels documented during hypoglycemia. Plasmapheresis led to remission of hypoglycemia. Antibodies to exogenous insulin should be considered as a cause of recurrent refractory hypoglycemia in type 1 diabetes mellitus patients.

  7. Hypertension og diabetes mellitus

    DEFF Research Database (Denmark)

    Poulsen, Per Løgstrup; Hansen, Klavs Würgler; Gaede, Peter Haulund

    2009-01-01

    The documentation for the beneficial effects of antihypertensive treatment in patients with diabetes is overwhelming. Most patients will require three or four antihypertensive drugs to achieve blood pressure (BP) goals. The regime should include an agent that blocks the renin angiotensin aldoster......The documentation for the beneficial effects of antihypertensive treatment in patients with diabetes is overwhelming. Most patients will require three or four antihypertensive drugs to achieve blood pressure (BP) goals. The regime should include an agent that blocks the renin angiotensin...

  8. 76 FR 9854 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0011] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  9. 78 FR 1923 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0350] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  10. 76 FR 9862 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0025] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  11. 78 FR 1927 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0351] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  12. 76 FR 64165 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-17

    ...-0277] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  13. 77 FR 533 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  14. 78 FR 38439 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  15. 77 FR 40941 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-11

    ...-0163] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  16. 77 FR 46149 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-02

    ...-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  17. 77 FR 64181 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-18

    ...-0283] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  18. 78 FR 26419 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ...-0018] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  19. 77 FR 52384 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-29

    ...-0218] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  20. 77 FR 56258 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-12

    ...-0219] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  1. 78 FR 38435 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0181] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  2. 76 FR 66120 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-25

    ...-0278] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  3. 78 FR 20381 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-04

    ...-0015] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  4. 77 FR 10612 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-0382] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  5. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ...-0193] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  6. Hypertension og diabetes mellitus

    DEFF Research Database (Denmark)

    Poulsen, Per; Hansen, Klavs; Gæde, Peter

    2009-01-01

    The documentation for the beneficial effects of antihypertensive treatment in patients with diabetes is overwhelming. Most patients will require three or four antihypertensive drugs to achieve blood pressure (BP) goals. The regime should include an agent that blocks the renin angiotensin aldoster...

  7. Resiliência de pessoas com Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Bárbara Cristina Tavares

    2011-01-01

    Full Text Available El estudio tuvo por objetivo investigar la resiliencia y las variables socio-demográficas y de salud/enfermedad de las personas con Diabetes Mellitus que acuden a un hospital general en Florianópolis, Santa Catarina, Brasil. Se trata de un estudio transversal, desarrollado con sesenta personas, en el periodo de agosto a noviembre de 2009, por medio de la Escala de Resiliencia Connor-Davidson. Los valores de resilencia fueron elevados, con una asociación entre resilencia y edad. Las personas atendidas en el servicio de urgencia presentaron valores de resilencia superiores al de las personas del ambulatorio y las unidades de internación. Llegamos a la conclusión que las personas con Diabetes Mellitus pueden tener puntuaciones más altas de resiliencia, compatibles con una población sana y de los países más desarrollados.

  8. Pancreatic scintiphotography in diabetes mellitus

    International Nuclear Information System (INIS)

    Nishimoto, Norimasa; Sowa, Etsuji; Fujii, Satoru; Seki, Junichi; Wada, Masahisa

    1975-01-01

    Pancreatic scintiphotography was performed in 108 cases of patients with diabetes mellitus. Scintiphotos were taken at 30 min. after intravenous injection of approximately 200μCi of 75 Se-selenomethionine using a Toshiba gamma camera. The relationship between the degree of pancreatic uptake of 75 Se-selenomethionine and the types and duration of diabetes, vascular complications and the average range of fasting blood sugar levels were studied. In some cases, pancreatic scintiphotos were taken at 10, 30 and 50 min. after injection of 75 Se-selenomethionine, and the degrees of the pancreatic uptake were compared on each time course. Only two out of 24 cases of insulin-dependent diabetics showed normal pancreatic scintiphotos. On the other hand, two out of 47 cases of mild diabetics treated with diet alone showed no uptake in pancreatic scintiphotos. There was a tendency toward abnormal pancreatic scintiphotos in chronic diabetics. Especially, of the 15 cases who had diabetes for more than eleven years, only one case showed a normal pancreatic scintiphoto. Abnormal pancreatic scintiphotos were found more frequently in the group of poorly controlled diabetics than in the group of well controlled diabetics. In cases showing normal pancreatic scintiphotos, diabetic retinopathy was less frequently found. Out of 36 cases which had sequential pancreatic scintiphotos, hypertension and/or arteriosclerosis were found more frequently in the 20 cases which showed a delay in reaching a plateau of the activity. However, the uptake in sequential pancreatic scintiphotos showed no definite correlation between diabetic retinopathy and other diabetic conditions. (auth.)

  9. Pancreatic scintiphotography in diabetes mellitus

    Energy Technology Data Exchange (ETDEWEB)

    Nishimoto, N; Sowa, E; Fujii, S; Seki, J; Wada, M [Osaka City Univ. (Japan). Faculty of Medicine

    1975-09-01

    Pancreatic scintiphotography was performed in 108 cases of patients with diabetes mellitus. Scintiphotos were taken at 30 min. after intravenous injection of approximately 200..mu..Ci of /sup 75/Se-selenomethionine using a Toshiba gamma camera. The relationship between the degree of pancreatic uptake of /sup 75/Se-selenomethionine and the types and duration of diabetes, vascular complications and the average range of fasting blood sugar levels were studied. In some cases, pancreatic scintiphotos were taken at 10, 30 and 50 min. after injection of /sup 75/Se-selenomethionine, and the degrees of the pancreatic uptake were compared on each time course. Only two out of 24 cases of insulin-dependent diabetics showed normal pancreatic scintiphotos. On the other hand, two out of 47 cases of mild diabetics treated with diet alone showed no uptake in pancreatic scintiphotos. There was a tendency toward abnormal pancreatic scintiphotos in chronic diabetics. Especially, of the 15 cases who had diabetes for more than eleven years, only one case showed a normal pancreatic scintiphoto. Abnormal pancreatic scintiphotos were found more frequently in the group of poorly controlled diabetics than in the group of well controlled diabetics. In cases showing normal pancreatic scintiphotos, diabetic retinopathy was less frequently found. Out of 36 cases which had sequential pancreatic scintiphotos, hypertension and/or arterioscl-erosis were found more frequently in the 20 cases which showed a delay in reaching a plateau of the activity. However, the uptake in sequential pancreatic scintiphotos showed no definite correlation between diabetic retinopathy and other diabetic conditions.

  10. La retinopatía diabética como predictor de morbi-mortalidad cardiovascular en pacientes con diabetes mellitus tipo 2 en un área de 70.000 habitantes de nuestra comunidad

    OpenAIRE

    Blasco Lamarca, Yolanda; Gimeno Orna, José Antonio; Faure Nogueras, Eduardo Jaime

    2013-01-01

    El elevado incremento en la morbi-mortalidad cardiovascular de los pacientes diabéticos, ha planteado la necesidad de búsqueda de marcadores de riesgo vascular. La presencia de retinopatía diabética podría ser un predictor independiente de riesgo de enfermedad cardiovascular. En una muestra de 463 pacientes con diabetes mellitus tipo 2 de nuestra comunidad autónoma hemos evaluado la relación entre la valoración inicial del fondo de ojo y la aparición de eventos cardiovasculares. Tras un seg...

  11. Diabetes mellitus and hypertension: a dual threat.

    Science.gov (United States)

    Oktay, Ahmet Afşin; Akturk, Halis Kaan; Jahangir, Eiman

    2016-07-01

    The following is a review of the current concepts on the relationship between hypertension (HTN) and diabetes mellitus with a focus on the epidemiology and cardiovascular prognostic implications of coexistent HTN and diabetes mellitus, shared mechanisms underlying both conditions and pathophysiology of increased risk of cardiovascular disease, treatment of HTN in individuals with diabetes mellitus, and effects of anti-diabetic medications on blood pressure (BP). Diabetes mellitus and HTN often coexist in the same individual. They share numerous risk factors and underlying pathophysiologic mechanisms, most important of which are insulin resistance and inappropriate activation of the rennin-angiotensin-aldosterone system. Recently updated guidelines recommend a BP goal of 140/90 mmHg in most individuals with diabetes mellitus. A new class of anti-diabetic medications, sodium-glucose co-transporter 2 inhibitors, has shown favorable effects on BP. HTN affects the majority of individuals with diabetes mellitus. Coexistence of diabetes mellitus and HTN, especially if BP is not well controlled, dramatically increases the risk of morbidity and mortality from cardiovascular disease. BP control is an essential part of management of patients with diabetes mellitus, because it is one of the most effective ways to prevent vascular complications and death.

  12. 77 FR 10607 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-2011-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The...). [[Page 10608

  13. Adaptación y validación del instrumento de calidad de vida Diabetes 39 en pacientes mexicanos con diabetes mellitus tipo 2 Adaptation and validation of quality of life instrument Diabetes 39 for Mexican patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Juan Manuel López-Carmona

    2006-06-01

    Full Text Available OBJETIVO: Adaptar y validar la versión al español del cuestionario Diabetes 39, que mide calidad de vida, en pacientes mexicanos con diabetes mellitus tipo 2 (DM-2 MATERIAL Y MÉTODOS: Encuesta transversal realizada en una unidad de medicina familiar. Un panel de investigadores adaptó el instrumento, que se aplicó en dos ocasiones, por autoadministración, a una muestra de 260 pacientes con DM-2. Se midieron la hemoglobina glucosilada (HbA1C, colesterol total, triglicéridos, tensión arterial, índice de masa corporal e índice cintura/cadera. Se obtuvieron datos sobre edad, sexo, tiempo de evolución, complicaciones diabéticas y comorbilidad RESULTADOS: Completaron el estudio 249 sujetos de los cuales 62.7% fueron mujeres. El alfa de Cronbach fue >0.80 para los dominios. La consistencia test-retest para la calificación total tuvo una r= 0.82, p= 0.01. La mediana de la puntuación total fue de 29 puntos (escala de 0 a 100 y se tomó como punto de corte para definir mejor (29 calidad de vida. En el análisis bivariado, una peor calidad de vida se asoció con complicaciones tardías de la diabetes >1 (RM= 1.73; IC95% 1.05-3.06; colesterol total >240 mg/dL (RM= 4.43; IC95% 1.23-16.26; comorbilidad >2 enfermedades (RM= 2.36; IC95% 1.31-4.28; evolución mayor a 10 años (RM= 2.19; IC95% 1.27-3.78 y HbA1C >8% (RM= 1.81; IC95% 1.09-2.99. Las tres últimas fueron predictoras de peor calidad de vida en la regresión logística (pOBJECTIVE:To adapt and validate the Spanish language version of the Diabetes 39 instrument, which measures quality of life, for Mexican patients with type 2 diabetes mellitus (DM-2 MATERIALS AND METHODS: The Spanish language version of the instrument was adapted to make it more comprehensible to Mexican patients. In a cross-sectional survey, the instrument was administered on two different days to 260 patients with type DM-2. Glycated hemoglobin (HbA1C, total cholesterol, triglycerides, blood pressure, body mass index and

  14. The perspectives of Brazilian homemakers concerning living with type 2 diabetes mellitus La perspectiva de ama de casa brasileña sobre la vida con diabetes mellitus tipo 2 As perspectivas de donas de casa brasileiras sobre a sua experiência com diabetes mellitus tipo 2

    OpenAIRE

    Denise Maria Guerreiro Vieira da Silva; Kathy Hegadoren; Gerri Lasiuk

    2012-01-01

    The purpose of this study is to present an understanding of the experience of Brazilian homemakers with type 2 diabetes mellitus (DM2). A descriptive exploratory design was used and semi-structured interviews were conducted with 25 Brazilian homemakers concerning their experience. The interviews were recorded, transcribed, and the resulting text was analyzed using the sequential step method. Data converged to one dominant category, "constructing one's identity in the family context", which is...

  15. Calcium homeostasis in diabetes mellitus.

    Science.gov (United States)

    Ahn, Changhwan; Kang, Ji-Houn; Jeung, Eui-Bae

    2017-09-30

    Diabetes mellitus (DM) is becoming a lifestyle-related pandemic disease. Diabetic patients frequently develop electrolyte disorders, especially diabetic ketoacidosis or nonketotic hyperglycemic hyperosmolar syndrome. Such patients show characteristic potassium, magnesium, phosphate, and calcium depletion. In this review, we discuss a homeostatic mechanism that links calcium and DM. We also provide a synthesis of the evidence in favor or against this linking mechanism by presenting recent clinical indications, mainly from veterinary research. There are consistent results supporting the use of calcium and vitamin D supplementation to reduce the risk of DM. Clinical trials support a marginal reduction in circulating lipids, and some meta-analyses support an increase in insulin sensitivity, following vitamin D supplementation. This review provides an overview of the calcium and vitamin D disturbances occurring in DM and describes the underlying mechanisms. Such elucidation will help indicate potential pathophysiology-based precautionary and therapeutic approaches and contribute to lowering the incidence of DM.

  16. Rheumatological manifestations of diabetes mellitus - a review ...

    African Journals Online (AJOL)

    ... strongly associated with diabetes mellitus including limited joint mobility, specific arthropathies of the hand (carpal tunnel syndrome, Dupytrens contracture, flexor tenosynovitis and diabetic sclerodactyly), shoulder (adhesive capsulitis-frozen shoulder, and calcific periarthritis) and spontaneous infarction of skeletal muscle.

  17. Musculoskeletal manifestations in type 2 diabetes mellitus

    OpenAIRE

    Deepti P. Deshmukh; Asmita G. Akarte

    2017-01-01

    Background: Musculoskeletal complications of diabetes have been generally ignored and poorly treated as compared to other complications. Hence we carried out this study to find the prevalence of musculoskeletal manifestations in type II diabetes mellitus and its correlation with age, BMI, duration of diabetes, and control of diabetes. Methods: 100 consecutive patients of type II diabetes were studied. Duration of diabetes, control of diabetes, and any musculoskeletal complaints were noted....

  18. Tratamiento de la diabetes mellitus tipo 2 en el municipio de Güines, año 2002: Análisis con énfasis en la terapia medicamentosa Treatment of type 2 diabetes mellitus in Güines municipality in the year 2002: Drug therapy-based analysis

    Directory of Open Access Journals (Sweden)

    José Luis Valenciaga Rodríguez

    2003-08-01

    Full Text Available Se realizó una investigación de corte transversal con el objetivo de identificar las características del tratamiento en personas con diabetes mellitus tipo 2 pertenecientes al municipio de Güines, en el año 2002, específicamente en la utilización de compuestos orales normo o hipoglucemiantes e insulina. El universo lo constituyeron 3 017 diabéticos tipo 2 registrados en el municipio en el año 2001, y la muestra 328 de estos casos, seleccionados a través de diseño muestral complejo (estratificado en la primera etapa y por conglomerados en la segunda. Los datos obtenidos se procesaron estadísticamente, con el empleo del programa SPSS (versión 10. La media de edad de la muestra fue de 65, 2 años y de 12,8 de la fecha de diagnóstico. Un total de 161 personas (49,1 % se trataba con dieta solamente y 42 con insulina; de ellos todos empleaban insulina de acción intermedia y 3 (7,1 % la de acción rápida. El compuesto hipoglucemiante más utilizado fue la Glibenclamida, en 131 casos (85,5 %, y su dosis media diaria fue de 15 mg, mientras aproximadamente 1 de cada 10 casos empleaba medicina verde. Se concluye que existen deficiencias en el manejo terapéutico, específicamente en la forma de utilización de insulina, escasa disponibilidad de compuestos orales normo o hipoglucemiantes y alta frecuencia de tratamiento no farmacológico. Se recomienda reanalizar el cumplimiento del Programa Nacional de Diabetes Mellitus en el municipio de Güines, con énfasis en la capacitación del personal de salud en aspectos terapéuticos, así como incrementar la disponibilidad de compuestos orales normo o hipoglucemiantes, específicamente de Metformin, en el municipio.A cross-sectional study was made to identify the characteristics of treatment of persons with type 2 diabetes mellitus in Güines municipality during 2002, particularly the use of oral normo or hypoglicemic compounds and insulin. The universe was made up of 3 017 type 2 diabetics

  19. Hypertension og diabetes mellitus

    DEFF Research Database (Denmark)

    Poulsen, Per Løgstrup; Hansen, Klavs Würgler; Gaede, Peter Haulund

    2009-01-01

    The documentation for the beneficial effects of antihypertensive treatment in patients with diabetes is overwhelming. Most patients will require three or four antihypertensive drugs to achieve blood pressure (BP) goals. The regime should include an agent that blocks the renin angiotensin...... aldosterone system. Reduction in albuminuria during antihypertensive treatment is indicative of renal and cardiovascular protection. Thus, if the level of albuminuria remains high, the treatment should be intensified, even in the light of achieved BP goals. Options for intensification are dual blockade......, supramaximal doses of ACE-I or ARB, or addition of aldosterone or renin-blocking agents. Long-term data are awaited regarding the optimal strategy for combination therapy. Patients on intensive antihypertensive treatment should be monitored regularly....

  20. Monogenic Forms of Diabetes: Neonatal Diabetes Mellitus and Maturity-Onset Diabetes of the Young

    Science.gov (United States)

    ... After Your Baby is Born Monogenic Diabetes Monogenic Diabetes (Neonatal Diabetes Mellitus & MODY) The most common forms of diabetes, ... from each parent. What are monogenic forms of diabetes? Some rare forms of diabetes result from mutations ...

  1. Relationship Between Diabetes Mellitus And Thyroid Disease ...

    African Journals Online (AJOL)

    Recent findings have evidenced the intricate bond between subclinical hypothyroidism and diabetes mellitus that contributes to major complications such as retinopathy and neuropathy. Insulin resistance has also been shown to play an indispensable role in connecting type 2 diabetes mellitus and thyroid dysfunction.

  2. Cambios citomorfométricos en células de la mucosa oral de pacientes con diabetes mellitus tipo 2. Evaluación de su utilidad diagnóstica

    Directory of Open Access Journals (Sweden)

    Andrés Cornejo

    2016-09-01

    Full Text Available La citología exfoliativa ha mostrado previamente cambios citomorfométricos en descamados celulares orales en pacientes con diabetes mellitus tipo 2 (DB2. El objetivo de esta investigación fue determinar la capacidad de identificar la presencia de DB2 a partir de estos cambios. Mediante citología exfoliativa oral de pacientes diabéticos (n=30 y controles (n=30 se obtuvieron (en dos registros, con intervalo de un mes los valores de diámetro nuclear (DN, diámetro citoplasmático (DC, proporción núcleo:citoplasma (RNC y presencia/ausencia de cariorrexis y binucleación. Además se registraron los valores de glicemia capilar y hemoglobina glicosilada (Hb1Ac. El grupo DB2 mostró un aumento estadísticamente significativo del DN y RNC (valor p<0,05, Test t de Student en comparación con los pacientes sin diabetes. También se observó una asociación entre cariorrexis y binucleación (valor p<0,005, Test exacto de Fisher con DB2. El modelo de regresión logística binaria, que incluyó las variables DN y DC, explicó pobremente la varianza del diagnóstico, con una especificidad y sensibilidad moderada para la clasificación de los pacientes con DB2. Las células de la mucosa oral de pacientes con DB2 presentan un mayor diámetro nuclear y RNC, correlacionándose con los valores de glicemia, sin embargo no es posible clasificar a partir de estos análisis si los pacientes poseen DB2.

  3. [Lifestyle of elderly patients with diabetes mellitus].

    Science.gov (United States)

    Fukuoka, Yuki; Yamada, Yuichiro

    2013-11-01

    In elderly people, glucose tolerance is deteriorated and the incidence of diabetes mellitus is increased, due to decreased muscle mass and physical activity, declining pancreatic beta cell function, and other factors. Diabetes mellitus is an important risk factor for arteriosclerosis development in the elderly. Precise diagnosis and adequate treatment are necessary to prevent cerebrovascular and ischemic heart diseases. Elderly patients with diabetes mellitus are characteristically afflicted with more complications, impaired activities of daily living, cognitive function decline, and family environment problems, as compared with young and middle-aged diabetics. Therefore, tailor-made rather than uniform therapy becomes important. Lifestyle modification is the basis of diabetes treatment. Herein, we describe "prevention and management" of diabetes mellitus, focusing on the lifestyles of elderly diabetics.

  4. 78 FR 63285 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... Mr. Van Gog understands diabetes management and monitoring, has stable control of his diabetes using...-0185] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs...

  5. Autocuidado de las adultas mayores con diabetes mellitus inscritas en el programa de enfermedades crónicas en Temoaya, México

    OpenAIRE

    Vianey Méndez Salazar

    2010-01-01

    Los sujetos de estudio fueron un total de diez adultas mayores con un promedio de 63 años, en la unidad de Saludde San Pedro Arriba, Municipio de Temoaya. La unidad de salud constituye un escenario para la capacitación delusuario, sin embargo se presentan condicionantes en las adultas mayores para no aplicar lo aprendido. El objetivode la investigación fue el describir las actividades de autocuidado en el adulto mayor con diabetes mellitustipo 2, inscritos al programa de enfermedades crónicas...

  6. Pattern of cutaneous manifestations in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Goyal Abhishek

    2010-01-01

    Full Text Available Background: Diabetes mellitus affects individuals of all ages and socioeconomic status. Skin is affected by the acute metabolic derangements as well as by chronic degenerative complications of diabetes. Aims: To evaluate the prevalence of skin manifestations in patients with diabetes mellitus. To analyze the prevalence and pattern of skin disorders among diabetic patients from this region of Western Himalayas. Materials and Methods: One hundred consecutive patients with the diagnosis of diabetes mellitus and having skin lesions, either attending the diabetic clinic or admitted in medical wards were included in this study. Results: The common skin disorders were: x0 erosis (44%, diabetic dermopathy (36%, skin tags (32%, cutaneous infections (31%, and seborrheic keratosis (30%. Conclusion: Skin is involved in diabetes quite often and the manifestations are numerous. High prevalence of xerosis in our diabetic population is perhaps due to cold and dry climatic conditions in the region for most of the time in the year.

  7. Monogenic diabetes mellitus in Norway

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    Oddmund Søvika

    2013-06-01

    Full Text Available Here, we review data on monogenic diabetes mellitus in Norway based on the Norwegian MODY Registry at Haukeland University Hospital, Bergen. This registry comprises established or suspected cases of maturity-onset diabetes of the young (MODY referred to our laboratory for genetic testing. We also present data on neonatal diabetes, another group of monogenic diabetes. To date, we have genetically diagnosed nearly 500 MODY cases in Norway. Mutations in the HNF1A gene (MODY3 were detected in about 50% of families with clinical MODY. GCK-MODY (MODY2 was the second most prevalent type, but may be underreported. We have also found mutations in the monogenic genes ABCC8, CEL, HNF1B, HNF4A, INS, KCNJ11 and NEUROD1. Based on genetic screening in the Norwegian MODY Registry and HUNT2, we estimate the number of MODY cases in Norway to be at least 2500-5000. Founder effects may determine the geographical distribution of MODY mutations in Norway. The molecular genetic testing of MODY and neonatal diabetes is mandatory for correct diagnosis and prognosis as well as choice of therapy

  8. Gestational diabetes mellitus screening and outcomes.

    Science.gov (United States)

    Aktün, Hale Lebriz; Uyan, Derya; Yorgunlar, Betül; Acet, Mustafa

    2015-01-01

    To verify the usefulness of the World Health Organization criteria for the diagnosis of gestational diabetes mellitus in pregnant women and its effectiveness in the prevention of maternal and neonatal adverse results in women younger than 35 years without apparent risk factors for gestational diabetes mellitus. This is a retrospective study based on population involving 1360 pregnant women who delivered and who were followed-up in a university hospital in Istanbul. All women underwent the 75-g oral glucose tolerance test screening, usually in between the 24(th)-28(th) weeks of pregnancy. In all cases, the identification of gestational diabetes mellitus was determined in accordance with the World Health Organization criteria. Approximately 28% of the pregnant women aged younger than 35 years with no risk factors for gestational diabetes mellitus were diagnosed with the oral glucose tolerance test in this study. In the gestational diabetes mellitus group, the primary cesarean section rate was importantly higher than that in the non-gestational diabetes mellitus group. Preterm delivery was also associated with gestational diabetes mellitus. The diagnosis of gestational diabetes mellitus was strongly associated with admittance to the neonatal intensive care unit. Neonatal respiratory problems didn't showed any significant deviation between the groups. There was a moderate association between gestational diabetes mellitus and metabolic complications. Pregnant women with no obvious risk factors were diagnosed with gestational diabetes mellitus using the World Health Organization criteria. The treatment of these women potentially reduced their risk of adverse maternal and neonatal hyperglycemia-related events, such as cesarean section, polyhydramnios, preterm delivery, admission to neonatal intensive care unit, large for gestational age, and higher neonatal weight.

  9. Factores de no adherencia al tratamiento en personas con Diabetes Mellitus tipo 2 en el domicilio. La visión del cuidador familiar Fatores de não aderência ao tratamento em pessoas com diabetes mellitus tipo 2 no domicílio. A visão do cuidador familiar Non adherence factors to treatment of people with type 2 Diabetes Mellitus at home. Family caregiver’s view

    Directory of Open Access Journals (Sweden)

    Teresa Nury Hoyos Duque

    2011-07-01

    Full Text Available Objetivo. Comprender los factores para no adherencia al trata- miento de personas con Diabetes Mellitus tipo 2 (DM2, desde la visión del cuidador familiar. Metodología. Estudio etnográfico enfocado. En 2008 se realizaron 18 entrevistas a cuidadores de pacientes con DM2, pertenecientes a programas de control de diabetes de instituciones de salud de Medellín (Colombia, y también se efectuaron seis observaciones de momentos significativos del cuidado. Resultados. La adherencia al tratamiento en personas con DM2 está mediada por múltiples factores que la dificultan como: concepciones culturales de la enfermedad, desencuentro entre los discursos del equipo profesional de salud y el saber popular, cansancio de tomar tantos medicamentos, miedo a la múltiples punciones por la aplicación de la insulina, insatisfacción con la calidad brindada de los servicios de salud y el costo económico de la enfermedad a largo plazo. Conclusión. Desde la visión de los cuidadores familiares, la adherencia al tratamiento de las personas con DM2 es escasa; hay múltiples factores que influyen en ello.Objetivo. Compreender os fatores para não aderência ao tratamento de pessoas com Diabetes Mellitus tipo 2 (DM2, desde a visão do cuidador familiar. Metodologia. Estudo etnográfico enfocado. Em 2008 se realizaram 18 entrevistas a cuidadores de pacientes com DM2, pertencentes a programas de controle de diabete de instituições de saúde de Medellín (Colômbia, e também se efetuaram seis observações de momentos significativos do cuidado. Resultados. A aderência ao tratamento em pessoas com DM2 está mediada por múltiplos fatores que a dificultam como: concepções culturais da doença, desencontro entre os discursos da equipe profissional de saúde e o saber popular, cansaço de tomar tantos medicamentos, medo à múltiplas punções pela aplicação da insulina, insatisfação com a qualidade brindada dos serviços de saúde e o custo econômico da doen

  10. Dry Fruits and Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Khan Sohaib A

    2017-04-01

    Full Text Available Dry fruits are some of the essential foods a human body requires staying healthy. They are made after extracting water from them. These fruits are full of essential nutrients including minerals, vitamins, enzymes, fibers and protect the body from a number of different adversities. These fruits are also a source of healthy nutrition among diabetic people who are very concerned about what to eat and what not to eat. But besides their countless benefits, these dry fruits can cause a number of harms to the body and therefore, must be used in a balanced way. This article is based on healthy and unhealthy effects of dry fruits and their use in diabetes mellitus.

  11. Periodontal disease and diabetes mellitus.

    Science.gov (United States)

    Negrato, Carlos Antonio; Tarzia, Olinda; Jovanovič, Lois; Chinellato, Luiz Eduardo Montenegro

    2013-01-01

    Periodontal disease (PD) is one of the most commonly known human chronic disorders. The relationship between PD and several systemic diseases such as diabetes mellitus (DM) has been increasingly recognized over the past decades. The purpose of this review is to provide the reader with knowledge concerning the relationship between PD and DM. Many articles have been published in the English and Portuguese literature over the last 50 years examining the relationship between these two chronic diseases. Data interpretation is often confounded by varying definitions of DM, PD and different clinical criteria were applied to determine the prevalence, extent and severity of PD, levels of glycemic control and diabetes-related complications. This paper provides a broad overview of the predominant findings from research conducted using the BBO (Bibliografia Brasileira de Odontologia), MEDLINE, LILACS and PubMed for Controlled Trials databases, in English and Portuguese languages published from 1960 to October 2012. Primary research reports on investigations of relationships between DM/DM control, PD/periodontal treatment and PD/DM/diabetes-related complications identified relevant papers and meta-analyses published in this period. This paper describes the relationship between PD and DM and answers the following questions: 1- The effect of DM on PD, 2- The effects of glycemic control on PD and 3- The effects of PD on glycemic control and on diabetes-related complications. The scientific evidence reviewed supports diabetes having an adverse effect on periodontal health and PD having an adverse effect on glycemic control and on diabetes-related complications. Further research is needed to clarify these relationships and larger, prospective, controlled trials with ethnically diverse populations are warranted to establish that treating PD can positively influence glycemic control and possibly reduce the burden of diabetes-related complications.

  12. Periodontal disease and diabetes mellitus

    Science.gov (United States)

    NEGRATO, Carlos Antonio; TARZIA, Olinda; JOVANOVIČ, Lois; CHINELLATO, Luiz Eduardo Montenegro

    2013-01-01

    Periodontal disease (PD) is one of the most commonly known human chronic disorders. The relationship between PD and several systemic diseases such as diabetes mellitus (DM) has been increasingly recognized over the past decades. Objective: The purpose of this review is to provide the reader with knowledge concerning the relationship between PD and DM. Many articles have been published in the english and Portuguese literature over the last 50 years examining the relationship between these two chronic diseases. Data interpretation is often confounded by varying definitions of DM, PD and different clinical criteria were applied to determine the prevalence, extent and severity of PD, levels of glycemic control and diabetes-related complications. Methods: This paper provides a broad overview of the predominant findings from research conducted using the BBO (Bibliografia Brasileira de Odontologia), MEDLINE, LILACS and PubMed for Controlled Trials databases, in english and Portuguese languages published from 1960 to October 2012. Primary research reports on investigations of relationships between DM/DM control, PD/periodontal treatment and PD/DM/diabetes-related complications identified relevant papers and meta-analyses published in this period. Results: This paper describes the relationship between PD and DM and answers the following questions: 1- The effect of DM on PD, 2- The effects of glycemic control on PD and 3- The effects of PD on glycemic control and on diabetes-related complications. Conclusions: The scientific evidence reviewed supports diabetes having an adverse effect on periodontal health and PD having an adverse effect on glycemic control and on diabetes-related complications. Further research is needed to clarify these relationships and larger, prospective, controlled trials with ethnically diverse populations are warranted to establish that treating PD can positively influence glycemic control and possibly reduce the burden of diabetes

  13. Construcción y validación inicial de un instrumento para medir el estilo de vida en pacientes con diabetes mellitus tipo 2 Development and initial validation of an instrument to measure lifestyle of type 2 diabetes mellitus patients

    Directory of Open Access Journals (Sweden)

    Juan Manuel López-Carmona

    2003-08-01

    Full Text Available OBJETIVO: Construir y validar un instrumento específico para medir el estilo de vida en los pacientes con diabetes mellitus tipo 2. MATERIAL Y MÉTODOS: Entre marzo de 2001 y abril de 2002 se hizo un estudio observacional, longitudinal y prospectivo en unidades de medicina familiar de la delegación Estado de México Oriente, del Instituto Mexicano del Seguro Social. Se diseñó un instrumento de autoadministración, denominado instrumento para medir el estilo de vida en diabéticos, el cual fue sometido a revisión por un panel multidisciplinario de expertos para determinar su validez lógica y de contenido. Se aplicó el instrumento en dos días diferentes a 412 sujetos adultos con diabetes mellitus. Fueron depurados los ítems considerando la frecuencia de selección de sus opciones de respuesta, su correlación ítem-total y su carga significativa en los dominios durante el análisis factorial. RESULTADOS: Completaron el estudio 389 (94.7% sujetos. Los coeficientes de correlación intra-clase para la validez lógica y de contenido fueron de 0.91 y 0.95, respectivamente. Después de la depuración de ítems se obtuvo un instrumento conformado por 25 preguntas cerradas, distribuidas en siete dominios: nutrición, actividad física, consumo de tabaco, consumo de alcohol, información sobre diabetes, emociones y adherencia terapéutica. El a de Cronbach para la calificación total fue de 0.81 y el coeficiente de correlación test-retest de 0.84. CONCLUSIONES: El instrumento para medir el estilo de vida en diabéticos es el primer cuestionario específico para sujetos con diabetes mellitus tipo 2 y tiene validez aparente, validez de contenido y buen nivel de consistencia.OBJECTIVE: To develop and validate a specific instrument to measure lifestyle of type 2 diabetes mellitus (DM2 patients. MATERIAL AND METHODS: A longitudinal, observational, prospective study was conducted between March 2001 and April 2002 at family medicine healthcare units of

  14. Estilos de vida: Experiencias con la adherencia al tratamiento no farmacológico en diabetes mellitus Life styles: Experiences joined from a nonfarmacological treatment in a diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Brenda Cintia Medel Romero

    2006-06-01

    Full Text Available El interés de realizar el presente estudio fue conocer las experiencias de las personas en el trascurso de un año, después de haber asistido a sesiones educativas donde se promovía la adherencia al tratamiento no farmacológico sobre diabetes mellitus tipo 2 en una comunidad semiurbana de la Ciudad de México. El estudio formó parte de los resultados del proyecto ESVIDIM-2 y fue financiado por el Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT, de la UNAM. Se realizó una entrevista semiestructurada, la cual fue grabada y trascrita íntegramente, para realizar un análisis de contenido. Los hallazgos se presentaron en dos categorías: experiencias que facilitan o estimulan la adherencia y experiencias que dificultan la adherencia. Se considera que el papel de la enfermera actualmente es contribuir en el establecimiento de estrategias para la adquisición y adherencia de estilos de vida saludables donde la persona se haga responsable de su propio cuidado incorporándolo en la toma de decisiones. Los resultados de este estudio ponen de manifiesto que la asistencia de las personas a sesiones educativas, tiene poco o ningún efecto en su salud, sin el seguimiento correspondiente del personal de salud para realizar asesorías, aclaraciones, actualizaciones y sobre todo un reforzamiento continuo de la motivación dirigida hacia el logro de un estado óptimo de salud.The interest to make this study was to now about experiences of the people in the course of a year, after to have attended educative sessions where the adhesion to a nonfarmacológical treatment is promoted for diabetes mellitus type 2 in an semiurban community of Mexico City. This study was part of the result from proyect ESVIDIM-2 and it was financed by the Program of Support to Projects of Investigation and Tecnological Innovation from UNAM. A semistructured interview was made which was recorded and transcribed completely, to make a content

  15. Perfil de diagnósticos de enfermagem em pessoas com diabetes segundo modelo conceitual de Orem Perfil de diagnósticos de enfermería en personas con diabetes según el modelo conceptual de Orem Nursing diagnoses in people with diabetes mellitus according to Orem's theory of self-care

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    Carla Regina de Souza Teixeira

    2009-01-01

    Full Text Available OBJETIVO: Identificar os diagnósticos de enfermagem em pessoas com diabetes mellitus, segundo o modelo conceitual de Orem. MÉTODOS: Participaram 31 pessoas com diabetes atendidas em um Centro Universitário de Pesquisa e Extensão, do interior paulista, em 2006. Os dados foram obtidos por meio de exame físico e entrevista dirigida de casos múltiplos. Os diagnósticos de enfermagem foram identificados segundo a Taxonomia II da NANDA, mediante o processo de raciocínio diagnóstico de Risner. RESULTADOS: Dos 37 diagnósticos de enfermagem, três apresentaram freqüência superior a 50%: controle ineficaz do regime terapêutico (67%, conhecimento deficiente (51% e integridade da pele prejudicada (51%. Dezoito diagnósticos de enfermagem estavam relacionados aos requisitos para o autocuidado universal, preconizado por Orem CONCLUSÃO: Os diagnósticos de enfermagem mostraram-se indicadores diferenciados para guiar as ações educativas do enfermeiro com enfoque no desenvolvimento das habilidades de autocuidado para pessoas com diabetes.OBJETIVO: Identificar los diagnósticos de enfermería en personas con diabetes mellitus, según el modelo conceptual de Orem. MÉTODOS: Participaron en el estudio 31 personas con diabetes atendidas en un Centro Universitario de Investigación y Extensión, del interior paulista, en el 2006. Los datos fueron obtenidos por medio de examen físico y entrevista dirigida de casos múltiples. Los diagnósticos de enfermería fueron identificados según la Taxonomía II de la NANDA, mediante el proceso de raciocinio diagnóstico de Risner. RESULTADOS: De los 37 diagnósticos de enfermería, tres presentaron frecuencia superior al 50%: control ineficaz del régimen terapéutico (67%, conocimiento deficiente (51% e integridad de la piel perjudicada (51%. Dieciocho diagnósticos de enfermería estaban relacionados a los requisitos para el autocuidado universal, preconizado por Orem. CONCLUSIÓN: Los diagnósticos de

  16. Lifestyle changes in descendants of parents with diabetes type 2 Cambio en los patrones de vida en descendientes de progenitores con diabetes mellitus tipo 2 del noreste de Mexico Mudança em os padrões de vida em descendentes de progenitores com diabetes mellitus tipo 2 do nordeste do México

    Directory of Open Access Journals (Sweden)

    Rosalinda Guerra-Juárez

    2007-10-01

    Full Text Available This study aimed to explore the disposition of diabetic parents' descendents in changing eating and physical activity patterns. It was based on the heritability concept and Prochaska's Transtheoretical Model. This is a descriptive-correlational study; participants included 30 parents, randomly selected, and 60 children. Results and conclusion: 68% of the children was classified as obese, 42% with insulin resistance, and 15% with carbohydrate intolerance. None of the risk factors was associated with the stages of change. The heritability factor was 1.37%; more people younger than 40 and women report decreasing in the consumption of fat food (Xi² = 6.04, p = .020; and 4.41, p = .040, respectively. These results suggest a high influence of environmental factors on the participants' unhealthy life styles.El objetivo general del estudio fue explorar la disposición al cambio de patrones alimentarios y actividad física en descendientes de progenitores con diabetes mellitus tipo 2 (DMT2, aplicando un diseño descriptivo correlacional. La base teórica la constituyó el componente genético heredabilidad (h² y el Modelo Transteorético de Prochaska; participaron 30 progenitores con DMT2 y 60 descendientes. Resultados y Conclusión: El 68% de los descendientes fueron obesos, 60% con riesgo de enfermedad cardiovascular, 42% con resistencia a la insulina (RI y 15% intolerantes a la glucosa; ninguno de los factores de riesgo se asoció con las etapas de cambio. El componente genético para RI fue mínimo (h² = 1.37%. Una mayor proporción de menores de 40 años (p = .020 y de mujeres "contemplan" disminuir el consumo de grasas (p = .040. Estos resultados sugieren un mayor peso de factores del medio ambiente sobre el estilo de vida nocivo de los participantes.O objetivo geral do estudo foi explorar à disposição à mudança dos padrões alimentares e atividade física nos descendentes de progenitores com diabetes mellitus tipo 2 (DMT2. Aplicou-se un

  17. Diabetes mellitus en el anciano, un problema frecuente Diabetes mellitus present in elderly, a common problem

    Directory of Open Access Journals (Sweden)

    Marelys Yanes Quesada

    2009-09-01

    Full Text Available La presencia de diabetes mellitus en la población anciana es un problema de salud frecuente en la atención primaria. Es por ello que en el presente trabajo pretendemos revisar algunos elementos importantes de este tema. Esta entidad se presenta habitualmente en estos pacientes, oligosintomática o de manera atípica, y los objetivos terapéuticos dependen de la situación funcional del enfermo. En relación con el tratamiento no farmacológico, la educación, la dieta y el ejercicio físico constituyen los pilares básicos; y respecto a la terapéutica farmacológica, se deben evitar las sulfonilureas de acción prolongada y de gran potencia. Las biguanidas pueden ser usadas para mejorar la sensibilidad a la insulina, y los inhibidores de la alfa glucosidasa son los medicamentos de elección cuando predomina la hiperglucemia posprandial. Las tiazolidinedionas deben ser usadas con precaución en pacientes con riesgo cardiovascular, y el uso de insulina está indicado en circunstancias especiales. Siempre se debe tener presente el tratamiento de la comorbilidad, para así tratar integralmente al anciano con diabetes mellitus.Presence of diabetes mellitus in elderlies is a common health problem in primary care. Thus, the aim of present paper is to review some significant elements of this matter. This entity is habitually present in these patients in a olisymptomatic way of in a atypical form, and therapeutic objectives depend on functional status of patient. With regard to non-pharmacological treatment, the education, diet, and physical exercise are the main basis; and regarding the pharmacological therapeutics, sulfonylurea of lengthy action and very potent must to be avoided. Biguanides may be used to improve insulin-sensitivity, and a-glycosidase inhibitors are the choice drugs when there is a predominance of postprandial hyperglycemia. The thiazolidinediones must to be used with precaution in patients presenting with cardiovascular risk, and

  18. Ayurvedic treatments for diabetes mellitus

    Science.gov (United States)

    Sridharan, Kalpana; Mohan, Roshni; Ramaratnam, Sridharan; Panneerselvam, Deepak

    2013-01-01

    Background Patients with diabetes frequently use complimentary and alternative medications including Ayurvedic medications and hence it is important to determine their efficacy and safety. Objectives To assess the effects of Ayurvedic treatments for diabetes mellitus. Search methods We searched The Cochrane Library (issue 10, 2011), MEDLINE (until 31 August 2011), EMBASE (until 31 August 2011), AMED (until 14 October 2011), the database of randomised trials from South Asia (until 14 October 2011), the database of the grey literature (OpenSigle, until 14 October 2011) and databases of ongoing trials (until 14 October 2011). In addition we performed hand searches of several journals and reference lists of potentially relevant trials. Selection criteria We included randomized trials of at least two months duration of Ayurvedic interventions for diabetes mellitus. Participants of both genders, all ages and any type of diabetes were included irrespective of duration of diabetes, antidiabetic treatment, comorbidity or diabetes related complications. Data collection and analysis Two authors independently extracted data. Risk of bias of trials was evaluated as indicated in the Cochrane Handbook for Systematic Reviews of Intervention. Main results Results of only a limited number of studies could be combined, in view of different types of interventions and variable quality of data. We found six trials of proprietary herbal mixtures and one of whole system Ayurvedic treatment. These studies enrolled 354 participants ( 172 on treatment, 158 on controls, 24 allocation unknown). The treatment duration ranged from 3 to 6 months. All these studies included adults with type 2 diabetes mellitus. With regard to our primary outcomes, significant reductions in glycosylated haemoglobin A1c (HbA1c), fasting blood sugar (FBS) or both were observed with Diabecon, Inolter and Cogent DB compared to placebo or no additional treatment, while no significant hypoglycaemic response was found

  19. Caracterización clínica y epidemiológica de los pacientes menores de 15 años de edad con diabetes mellitus tipo 1 Clinical-epidemiologic characterization of patients aged under 15 presenting with type 1 diabetes mellitus

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    Juliette Navarrete Cabrera

    2012-04-01

    Full Text Available Objetivo: identificar las características clínico epidemiológicas de los pacientes menores de 15 años de edad, diagnosticados con diabetes mellitus tipo 1 durante el período comprendido entre el 1º de enero de 2000 y el 31 de diciembre de 2008 de la provincia Ciudad de La Habana. Métodos: se realizó un estudio descriptivo-retrospectivo con los pacientes menores de 15 años de edad, diagnosticados con diabetes mellitus tipo 1 durante el período ya mencionado. El grupo de estudio estuvo constituido por 293 pacientes, a los que se realizó la revisión de la historia clínica. Las variables estudiadas fueron: sexo, edad al diagnóstico, color de la piel, duración de lactancia materna exclusiva, forma clínica al diagnóstico y factores ambientales. Se realizó el análisis estadístico mediante cálculo de por cientos y de tasas de incidencia por grupo de edad y sexo durante el período estudiado. Resultados: los resultados más importantes mostraron un predominio de los pacientes que recibieron lactancia materna exclusiva por un tiempo menor de 3 meses. Las formas clínicas menos graves al diagnóstico de la enfermedad fueron las más frecuentes. Entre los factores ambientales predominaron las enfermedades respiratorias agudas. La tasa de incidencia media del período fue de 8,4 x 100 000 habitantes. Conclusiones: la incidencia de la enfermedad durante el período fue más alta en relación con los estudios previos realizados en el país, con un desplazamiento hacia edades tempranas.Objective: to identify the clinical-epidemiologic features of the patients aged under 15, diagnosed with type 1 diabetes mellitus from January 1, 2000 to December 31, 2008 from Ciudad de La Habana province. Methods: a descriptive-retrospective study was conducted in patients aged under 15 diagnosed with type 1 diabetes mellitus over above mentioned period. The study group included 293 patients and the review of medical record. Study variables were: sex, age

  20. Prothrombotic changes in diabetes mellitus.

    Science.gov (United States)

    Morel, Olivier; Jesel, Laurence; Abbas, Malak; Morel, Nicolas

    2013-07-01

    Although our understanding of vascular pathology has greatly improved in recent years, the cellular and molecular mechanisms underlying the enhanced thrombotic propensity in type 2 diabetes mellitus (T2DM) remain incompletely characterized. Detrimental interactions between activated vascular cells (i.e., platelets, leukocytes, endothelial cells) and the vulnerable atheromatous plaque are a major determinant of the increased atherothrombotic burden in T2DM patients. Endothelial damage and accelerated senescence, impairment of the endothelial progenitor cell repair system, plaque neovascularization and inflammation, decreased clearance of detrimental molecules within the plaque, and increased expression of matrix metalloproteinases may collectively contribute to intraplaque hemorrhage and subsequent rupture. Notably, recent data demonstrates the central importance of the tissue factor-microparticle-mediated pathway in diabetic thrombophilia and cardiovascular complications. Acting as detrimental amplifiers of various biological responses (including thrombogenicity and plaque remodeling), microparticles have also emerged as a key marker of global vascular damage in T2DM patients. Available evidence suggests that targeting the tissue factor-microparticle pathway may be a promising approach for reducing the burden of the atherosclerotic complications of diabetes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  1. Prevalence of pre-diabetes and unreported diabetes mellitus in ...

    African Journals Online (AJOL)

    Background: Unreported diabetes mellitus and glucose intolerance have substantial clinical importance. Glucose intolerance precedes diabetes mellitus and it is associated with cardiovascular complications. Subjects with prediabetes have near normal glycated haemoglobin and may only be detected when oral glucose ...

  2. Stress and adjustment in diabetes mellitus.

    Science.gov (United States)

    Parveen, S; Singh, S B

    1999-01-01

    Stress and adjustment in diabetics is studied in order to know the influence of maladjustment and stress in the causation of the disease. The sample of study consists of 100 diabetics patients, 100 nonpsychosomatic and 100 normal person. Results obtained are discussed in detail. It is concluded that maladjustment and stress are important contributing factors in' diabetes mellitus.

  3. Antioxidant plants and diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Hamid Nasri

    2015-01-01

    Full Text Available The incidence of diabetes mellitus (DM is increasing rapidly and it is expected to increase by 2030. Other than currently available therapeutic options, there are a lot of herbal medicines, which have been recommended for its treatment. Herbal medicines have long been used for the treatment of DM because of the advantage usually having no or less side-effects. Most of these plants have antioxidant activities and hence, prevent or treat hard curable diseases, other than having the property of combating the toxicity of toxic or other drugs. In this review other than presenting new findings of DM, the plants, which are used and have been evaluated scientifically for the treatment of DM are introduced.

  4. Knowledge of Diabetes Mellitus among Registered Nurses in Benin ...

    African Journals Online (AJOL)

    Knowledge of Diabetes Mellitus among Registered Nurses in Benin City. ... Although, nurses knew that diet plays a great role in management of diabetes mellitus, they were ... Keywords: Nurses, Health education, Understanding of diabetes.

  5. 77 FR 3549 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-24

    ...-0368] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  6. 77 FR 5873 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-06

    ...-2011-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... diabetes exemption applications from fifteen individuals and requested comments from the public (76 FR...

  7. 78 FR 14406 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-03-05

    ...-0013] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  8. 76 FR 61140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ...-0194] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  9. 77 FR 70530 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-11-26

    ...-0348] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  10. 77 FR 65931 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-31

    ...-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of applications from 12 individuals for exemption from the prohibition against persons with insulin-treated diabetes...

  11. ORIGINAL ARTICLE Undiagnosed Diabetes Mellitus and ...

    African Journals Online (AJOL)

    2018-01-01

    Jan 1, 2018 ... School of Biomedical and Laboratory. Sciences, College .... implementing quality control measures during the whole process .... Table 2: Prevalence of undiagnosed diabetes mellitus by behavioral characteristics, clinical and.

  12. 139 PREVENTION AND SCREENING FOR DIABETES MELLITUS ...

    African Journals Online (AJOL)

    drclement

    2009-12-01

    Dec 1, 2009 ... PREVENTION AND SCREENING FOR DIABETES MELLITUS. *G.U. Eze ... Public Health is the science and art of preventing ... nutrition that targeted only healthy people with ... to such activities as Health education against.

  13. Uso de la crema Vimang® en la cicatrización alveolar después de la extracción dentaria en un paciente con diabetes mellitus

    OpenAIRE

    Alemán Miranda, Otto; Corona Carpio, Marcia Hortensia; Domínguez Rodríguez, Yamila

    2017-01-01

    Se presenta el caso clínico de un anciano de 75 años de edad, con antecedentes de hipertensión arterial y diabetes mellitus, quien acudió a consulta estomatológica para que le extrajeran el segundo molar inferior izquierdo por presentar gran destrucción debido a caries dental. Después de concluir el proceder se le aplicó la crema Vimang® directamente en el alveolo para acelerar los procesos de cicatrización y evitar cualquier complicación inmediata o mediata; luego se indicó 4 veces al día de...

  14. Calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes LADA

    OpenAIRE

    Granado Casas, Minerva

    2014-01-01

    Introducción: La calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes mellitus están relacionados con el control metabólico, las complicaciones y algunas variables socioeconómicas. Actualmente, no existe ningún estudio científico que analice la calidad de vida, satisfacción con el tratamiento y bienestar emocional en pacientes con diabetes LADA. Objetivos: Los objetivos principales fueron conocer la calidad de vida, satisfacción con el tratamient...

  15. Antioxidantes y diabetes mellitus: revisión de la evidencia Antioxidants and diabetes mellitus: review of the evidence

    OpenAIRE

    C. Cuerda; L. M. Luengo; M. A. Valero; A. Vidal; R. Burgos; F. L. Calvo; C. Martínez

    2011-01-01

    Introducción: En la diabetes mellitus existe un aumento del estrés oxidativo y una disminución de los sistemas de defensa antioxidante, que se han implicado en la etiopatogenia de la enfermedad y en la aparición de complicaciones crónicas. Metodología: Realizamos una revisión no sistemática con el objetivo de evaluar la relación entre el estrés oxidativo y la diabetes, y los posibles efectos de los antioxidantes en la prevención y tratamiento de la diabetes y sus complicaciones. Resultados: L...

  16. Readiness for enhanced self-health management among people with diabetes mellitus Disposición para el control aumentado del régimen terapéutico entre personas con diabetes mellitus Disposição para controle aumentado do regime terapêutico entre pessoas com diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Márcio Flávio Moura de Araújo

    2012-01-01

    Full Text Available OBJECTIVE: To identify the nursing diagnosis, readiness for enhanced self-health management, among people with type 2 diabetes who are adherent to pharmacological treatment. METHODS: The sample consisted of 579 subjects from 12 primary care services who received home visits. To determine adherence to the pharmacological treatment, the pill count test was conducted. Those classified as adherent were given a checklist with the defining characteristics of the nursing diagnosis, readiness for enhanced self-health management. RESULTS: Subjects with type 2 diabetes who presented with the nursing diagnosis were not alcoholics (p = 0.003, did not miss their diabetes consultations (p = 0.000, and had no difficulties / inappropriate behaviors with regard to taking their oral antidiabetic agents (p = 0.000. CONCLUSION: The identification of human responses to the clinical treatment of type 2 diabetes should be continuous, so that nurses can understand the factors involved in the readiness to enhance therapeutic control.OBJETIVO: identificar el diagnóstico de enfermería disposición para el control aumentado del régimen terapéutico entre personas con diabetes tipo 2 adheridas al tratamiento farmacológico. MÉTODOS: La muestra estuvo constituida por 579 sujetos de 12 servicios de atención primaria que recibieron visitas domiciliarias. Para determinar la adhesión al tratamiento farmacológico fue realizado el test del recuento de comprimidos. En aquellos clasificados como adherentes se aplicó un check list con las características definidoras del diagnóstico de enfermería disposición para el control aumentado del régimen terapéutico. RESULTADOS: Los sujetos con DM 2 que presentaron el diagnóstico de enfermería estudiado no eran etílicos (p=0,003, no faltaban a las consultas para DM 2 (p=0,000 y no tenían dificultades/comportamientos inadecuados en la toma de los antidiabéticos orales (p=0,000. CONCLUSIÓN: La identificación de respuestas

  17. Low dose radiation and diabetes mellitus

    International Nuclear Information System (INIS)

    Zhao Hongguang; Gong Shouliang; Cai Lu

    2006-01-01

    Induction of hormesis and adaptive response by low-dose radiatio (LDR) has been extensively indicated. It's mechanism may be related with the protective protein and antioxidants that LDR induced, which take effects on the diabetes mellitus (DM) and other diseases. This review will summarize available dat with emphasis on three points: the preventive effect of LDR on the development of diabetes, the therapeutic effect of LDR on diabetic complications and possible mechanisms by which LDR prevents the development of diabetes and diabetic complications. Finally, the perspectives of LDR clinical, diabetes-related implication are discussed. (authors)

  18. Therapeutic Lifestyle Changes for Diabetes Mellitus.

    Science.gov (United States)

    Levesque, Celia

    2017-12-01

    Diabetes mellitus is a common chronic disease affecting approximately 9% of the United States population. Successful management of diabetes demands constant self-management on the part of the patient. The patient has to balance diabetes medications, blood glucose monitoring, food intake, physical activity, and management of diabetes-related acute and chronic complications. The patient is often bombarded with misinformation from friends, relatives, and such sources as the Internet and social media. This article discusses the current recommendations for diabetes self-management education and skills including medical nutrition therapy, physical activity, smoking cessation, and assessment for diabetes distress. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. NUEVOS FÁRMACOS EN DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    DRA. Carmen Gloria Aylwin H.

    2016-03-01

    Full Text Available Por más de 60 años se dispuso solo de tres grupos farmacológicos para el tratamiento de la diabetes mellitus (DM: la insulina, la metformina y las sulfonilureas. Sin embargo, en los últimos años y como consecuencia de los avances en el conocimiento de la patogenia de la DM2 se han desarrollado nuevos fármacos con novedosos mecanismos de acción y con diferentes perfiles de seguridad, entre ellos los compuestos con efecto incretina y los glucosúricos que actúan en los trastornos a nivel intestinal y renal presentes en la DM2. La disponibilidad de múltiples opciones terapéuticas está produciendo profundos cambios en la terapia farmacológica de la DM2. Se logran enfoques terapéuticos más fisiopatológicos pero sobre todo permiten un manejo más personalizado y ajustado a las características y riesgos individuales de los pacientes, privilegiando junto al control glicémico, la seguridad terapéutica. En esta revisión se analizarán los nuevos fármacos con efecto incretina, los agonistas del péptido similar al glucagón tipo 1 (AR-GLP1 e inhibidores de la dipeptidil peptidasa 4 (IDPP-4, y los inhibidores de los cotransportadores sodio-glucosa tipo 2 (ISLGT2 que aumentan la excreción renal de glucosa.

  20. Diabetes mellitus en adultos mayores costarricenses

    Directory of Open Access Journals (Sweden)

    Rosero-Bixby, Luis

    2007-07-01

    Full Text Available El propósito del artículo es describir la prevalencia de la diabetes mellitus (DM entre los adultos mayores costarricenses. Se analiza la magnitud de la prevalencia, los problemas de medición de la misma, así como los factores asociados con la enfermedad, la enfermedad controlada, y el tener niveles altos de hemoglobina glicosilada (HbA1C entre la población sin diagnóstico previo de DM. Una cuarta parte de los adultos mayores de Costa Rica padecen de DM y cerca de la mitad de los que la padecen, no la tienen controlada. Los factores asociados con la prevalencia de la enfermedad son los usuales destacados por la literatura científica: actividad física, obesidad e historia familiar de DM. Se halla evidencia de un posible problema de acceso diferencial a servicios de control de DM, ya que los adultos mayores que habitan fuera de la gran área metropolitana de San José tienen un riesgo menor de tener controlada su enfermedad. Los adultos mayores sin pensión también tienen un riesgo mayor de tener niveles altos de HbA1C.

  1. Diabetes mellitus en adultos mayores costarricenses

    Directory of Open Access Journals (Sweden)

    Gilbert Brenes-Camacho

    2007-01-01

    Full Text Available El propósito del artículo es describir la prevalencia de la diabetes mellitus (DM entre los adultos mayores costarricenses. Se analiza la magnitud de la prevalencia, los problemas de medición de la misma, así como los factores asociados con la enfermedad, la enfermedad controlada, y el tener niveles altos de hemoglobina glicosilada (HbA1C entre la población sin diagnóstico previo de DM. Una cuarta parte de los adultos mayores de Costa Rica padecen de DM y cerca de la mitad de los que la padecen, no la tienen controlada. Los factores asociados con la prevalencia de la enfermedad son los usuales destacados por la literatura científica: actividad física, obesidad e historia familiar de DM. Se halla evidencia de un posible problema de acceso diferencial a servicios de control de DM, ya que los adultos mayores que habitan fuera de la gran área metropolitana de San José tienen un riesgo menor de tener controlada su enfermedad. Los adultos mayores sin pensión también tienen un riesgo mayor de tener niveles altos de HbA1C.

  2. [Position statement: surgery and diabetes mellitus].

    Science.gov (United States)

    Fasching, Peter; Huber, Joakim; Clodi, Martin; Abrahamian, Heidemarie; Ludvik, Bernhard

    2016-04-01

    This position statement reflects the opinion of the Austrian Diabetes Association concerning the perioperative management of patients with diabetes mellitus based on the available scientific evidence. The paper covers necessary preoperative examinations from an internal/diabetological point of view as well as the perioperative metabolic control by means of oral antidiabetics and/or insulin therapy.

  3. Changing trends in diabetes mellitus in pregnancy.

    LENUS (Irish Health Repository)

    Khalifeh, A

    2014-02-01

    The purpose of this study was to identify any changing trends in the incidence and caesarean section (CS) rate of pre-gestational diabetes mellitus (DM) and gestational diabetes mellitus (GDM) over a 10- year period, between 1999 and 2008. Although the incidence of pre-gestational DM has not significantly changed over the course of the last 10 years, there is an obvious rising trend in the incidence of GDM. Despite an increase in the overall CS rate during this time period, a parallel increase in the CS rate has not been observed among women whose pregnancies are complicated either by gestational or by pre-gestational diabetes (PGD).

  4. Diabetes mellitus in a toco toucan.

    Science.gov (United States)

    Douglass, E M

    1981-04-01

    Diabetes mellitus is rarely diagnosed in avian species. The majority of reported cases have occurred in small birds, such as the parakeet and canary. A major complicating factor in the diagnosis of diabetes in birds is the lack of accepted normal blood glucose values, which can be highly variable among avian species. In the case to be reported here a Toco Toucan (Ramphastos toco) was affected. The diagnosis of diabetes mellitus in this instance was based on the history, clinical signs, and response to therapy.

  5. Osteoporosis and diabetes mellitus: a modern viewpoint

    OpenAIRE

    N A Molitvoslovova; G R Galstyan

    2013-01-01

    The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), – or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterio...

  6. Knowledge of diabetic complications in patients with diabetes mellitus

    International Nuclear Information System (INIS)

    Ullah, F.; Afridi, A.K.; Rahim, F.; Ashfaq, M.; Khan, S.

    2015-01-01

    The prevalence of diabetes mellitus has risen exponentially over the last three decades, with resultant increase in morbidity and mortality mainly due to its complications. Limited data is available regarding the awareness and knowledge about these complications in our population. This study was carried out to evaluate the knowledge of diabetic complications in patients with diabetes mellitus. Methods: This cross-sectional study was conducted in the Medical B Unit of Department of Medicine Khyber Teaching Hospital, Peshawar. All admitted diabetic patients above 15 years of age with duration of diabetes mellitus more than one year were included. Results: Out of the 96 patients questioned, 58 were females and 38 were males. Mean age was 53.29 ± 10.821 years while the mean duration of diabetes mellitus was 9.75 ± 7.729 years. Of the total 76 (79.1%) of the patients were illiterate; 36 (37.50%) had good, 24 (25%) had average and 36 (37.50%) had poor knowledge about diabetic complications. Males and university graduate patients had slightly better knowledge. Between 50-60% patients were aware of different cardiac complications of diabetes mellitus. Awareness regarding other complications was foot ulcer/gangrene 70 (72.91%), poor wound healing 68 (70.83%), stroke 54 (56.25%), renal diseases 64 (66.66%), eye diseases 53 (55.20%), gastroparesis and other gastrointestinal problems 45 (46.87%), diabetic ketoacidosis 55 (57.29%), hypoglycaemia 50 (52.08%), lipid abnormalities 26 (27.08%) and symptoms of diabetic neuropathy ranging from 47-65%. Conclusions: Majority of diabetic patients are unaware of diabetic complications. Therefore, hospital and community based awareness programs should be launched to decrease the morbidity and mortality associated with diabetes mellitus. (author)

  7. KNOWLEDGE OF DIABETIC COMPLICATIONS IN PATIENTS WITH DIABETES MELLITUS.

    Science.gov (United States)

    Ullah, Fahim; Afridi, Ayesha Khan; Rahim, Fawad; Ashfaq, Muhammad; Khan, Sheema; Shabbier, Ghulam; Rahman, Sadiq Ur

    2015-01-01

    The prevalence of diabetes mellitus has risen exponentially over the last three decades, with resultant increase in morbidity and mortality mainly due to its complications. Limited data is available regarding the awareness and knowledge about these complications in our population. This study was carried out to evaluate the knowledge of diabetic complications in patients with diabetes mellitus. This cross-sectional study was conducted in the Medical B Unit of Department of Medicine Khyber Teaching Hospital, Peshawar. All admitted diabetic patients above 15 years of age with duration of diabetes mellitus more than one year were included. Out of the 96 patients questioned, 58 were females and 38 were males. Mean age was 53.29 +/- 10.821 years while the mean duration of diabetes mellitus was 9.75 +/- 7.729 years. Of the total 76 (79.1%) of the patients were illiterate; 36 (37.50%) had good, 24 (25%) had average and 36 (37.50%) had poor knowledge about diabetic complications. Males and university graduate patients had slightly better knowledge. Between 50-60% patients were aware of different cardiac complications of diabetes mellitus. Awareness regarding other complications was foot ulcer/gangrene 70 (72.91%), poor wound healing 68 (70.83%), stroke 54 (56.25%), renal diseases 64 (66.66%), eye diseases 53 (55.20%), gastroparesis and other gastrointestinal problems 45 (46.87%), diabetic ketoacidosis 55 (57.29%), hypoglycaemia 50 (52.08%), lipid abnormalities 26 (27.08%) and symptoms of diabetic neuropathy ranging from 47-65%. Majority of diabetic patients are unaware of diabetic complications. Therefore, hospital and community based awareness programs should be launched to decrease the morbidity and mortality associated with diabetes mellitus.

  8. Nailfold capillaroscopy in diabetes mellitus.

    Science.gov (United States)

    Maldonado, G; Guerrero, R; Paredes, C; Ríos, C

    2017-07-01

    Diabetes mellitus (DM) is characterized by chronic hyperglycemia states and the development of specific microvascular disorders such as retinopathy and nephropathy. Conventional methods are used to study the vascular compromise of this entity, however, the use of capillaroscopy for the evaluation of capillary microarchitecture is not frequently used. Observational and descriptive study of 65 patients with an established diagnosis of DM and a control group that underwent an initial capillaroscopy examination. The parameters considered were: Capillary diameter (ectasia and giant capillaries), cross-linked, tortuous, arborified capillaries, avascular zones, haemorrhages, dominant morphology, visibility of the subpapillary venous plexus (SPVP), cuticulitis and SD pattern. Capillaroscopy was performed in 65 patients, the findings were: tortous capillaries (63%), crosslinked capillaries (59%), avascular areas (48%), ectasias (39%), giant capillaries (11%). The capillaroscopic findings were evident in the majority of the studied population, 83%, compared to 17% who did not have capillaroscopic alterations. Significant capillaroscopic changes were demonstrated in patients with DM, in turn, we described a specific pattern consisting of: capillary dilatation, avascular zones and tortuous capillaries. Patients with more comorbidities and evolution of the disease showed greater microvascular damage. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Pharmacogenetics of posttransplant diabetes mellitus.

    Science.gov (United States)

    Lancia, P; Adam de Beaumais, T; Jacqz-Aigrain, E

    2017-06-01

    Many factors (physiological, pathological, environmental or genetic) are associated with variability in drug effect. Most patients respond to a standard treatment but the drug may be ineffective or toxic. In this review, we focused on genetic markers of posttransplant diabetes mellitus (PTDM) after renal transplantation, a frequent complication of immunosuppressive therapy and important risk factor of graft loss and mortality. An initial literature search identified 100 publications and among them 32 association studies were retrieved under 'Pharmacogenetics and PTDM'. Thirty-five variants in 25 genes with an impact on insulin secretion, disposition or effect were significantly associated with PTDM. The population studied, immunosuppressive regimen, follow-up, PTDM diagnostic and genetic variations tested were highly variable between studies. Although pharmacogenetic biomarkers are key tools of great promise for preventing toxicities and improving event-free survival rates, replication studies are required to select validated biomarkers linked to the occurrence of PTDM and select appropriate immusuppressive treatment to improve renal graft and patient outcome.

  10. Outcomes of polytrauma patients with diabetes mellitus

    Science.gov (United States)

    2014-01-01

    Background The impact of diabetes mellitus in patients with multiple system injuries remains obscure. This study was designed to increase knowledge of outcomes of polytrauma in patients who have diabetes mellitus. Methods Data from the Trauma Audit and Research Network was used to identify patients who had suffered polytrauma during 2003 to 2011. These patients were filtered to those with known outcomes, then separated into those with diabetes, those known to have other co-morbidities but not diabetes and those known not to have any co-morbidities or diabetes. The data were analyzed to establish if patients with diabetes had differing outcomes associated with their diabetes versus the other groups. Results In total, 222 patients had diabetes, 2,558 had no past medical co-morbidities (PMC), 2,709 had PMC but no diabetes. The diabetic group of patients was found to be older than the other groups (P <0.05). A higher mortality rate was found in the diabetic group compared to the non-PMC group (32.4% versus 12.9%), P <0.05). Rates of many complications including renal failure, myocardial infarction, acute respiratory distress syndrome, pulmonary embolism and deep vein thrombosis were all found to be higher in the diabetic group. Conclusions Close monitoring of diabetic patients may result in improved outcomes. Tighter glycemic control and earlier intervention for complications may reduce mortality and morbidity. PMID:25026864

  11. Managing hypertension in type 2 diabetes mellitus.

    Science.gov (United States)

    Horr, Samuel; Nissen, Steven

    2016-06-01

    Hypertension is a common problem in the diabetic population with estimates suggesting a prevalence exceeding 60%. Comorbid hypertension and diabetes mellitus are associated with high rates of macrovascular and microvascular complications. These two pathologies share overlapping risk factors, importantly central obesity. Treatment of hypertension is unequivocally beneficial and improves all-cause mortality, cardiovascular mortality, major cardiovascular events, and microvascular outcomes including nephropathy and retinopathy. Although controversial, current guidelines recommend a target blood pressure in the diabetic population of diabetes. Management of blood pressure in patients with diabetes includes both lifestyle modifications and pharmacological therapies. This article reviews the evidence for management of hypertension in patients with type 2 diabetes mellitus, and provides a recommended treatment strategy based on the available data. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Diabetes mellitus in newborns and infants.

    Science.gov (United States)

    Menon, P S; Khatwa, U A

    2000-06-01

    Diabetes mellitus is uncommon in infancy and newborn period. The two common forms seen are the transient and permanent forms of diabetes mellitus of the newborn. They have to be differentiated from the transient hyperglycemic states (Blood sugar > 125 mg/dl) seen in newborns who receive parenteral glucose infusions and in those with septicemia and CNS disorders. Transient diabetes mellitus of the newborn (TDNB) is defined as hyperglycemia occurring within the first month of life lasting at least 2 weeks and requiring insulin therapy. Most of these cases resolve spontaneously by 4 months. It has a reported incidence of 1 in 45,000 to 60,000 live births. The most likely etiology is a maturational delay of cAMP mediated insulin release. The clinical features include small for datedness, proneness for birth asphyxia, open-eye alert facies, dehydration, emaciation, polyuria and poydipsia. These children are prone to septicemia and urinary tract infections. They have hyperglycemia, glucosuria, absent or mild ketonuria, low basal insulin, C-peptide and IGF-1 levels. Treatment consists of hydration and judicious administration of insulin with close monitoring. Thirty percent of these children are likely to develop permanent neonatal diabetes. Compared to transient form, permanent diabetes mellitus is uncommon. It is usually due to pancreatic dysgenesis often associated with other malformations and rarely due to type 1 diabetes mellitus. The diagnosis is based on the demonstration of both exocrine and endocrine pancreatic dysfunction. These children are managed as type 1 diabetes mellitus. They are prone to develop the vascular complications of diabetes at an earlier date.

  13. Evaluación periodontal de pacientes portadores de diabetes mellitus Periodontal evaluation of patients with diabetes mellitus.

    Directory of Open Access Journals (Sweden)

    Carlos Rogério Ribeiro Fontanini

    2006-08-01

    Full Text Available Los portadores de diabetes mellitus presentan manifestaciones sistémicas que pueden interferir en la atención odontológica. El riesgo de periodontitis aumenta cuando el paciente está descompensado metabólicamente. El objetivo de nuestra investigación fue evaluar las condiciones periodontales relacionadas en pacientes con diabetes mellitus. Se examinaron 57 pacientes portadores de diabetes. Las condiciones periodontales fueron evaluadas por el índice CPITN. Se constató un inadecuado control metabólico, pues 38 pacientes (66,67 % se encontraban con niveles glicémicos alterados. Se evaluaron en total 342 sextantes y 49 fueron considerados válidos para examen. Los códigos 0 y 1 estuvieron representados por un paciente cada uno; el código 2 fue observado en 11 sextantes examinados; el código 3 en 18 y el código 4 en 22 de estos. Concluimos que la enfermedad periodontal es muy severa en diabéticos. En función de las manifestaciones bucales encontradas en esos pacientes, podemos sugerir que individuos portadores de diabetes mellitus representan un grupo especial que requiere medidas odontológicas preventivas y terapéuticas específicas.Diabetes mellitus carriers show systemic manifestations that may interfere with odontological care. The risk of periodontitis increases with metabolic decompensation of a patient. The objective of our research work was to evaluate the periodontal condition in patients with diabetes mellitus. Fifty seven diabetic patients were examined. CPITN index served to assess the periodontal conditions. It was established that metabolic control was inadequate since 38 patients (66,67% presented with altered glycemic levels. Three hundred and forty two sextants were assessed, 49 of which were considered valid for test. Codes 0 and 1 were represented by one patient each; code 2 was observed in 11 analyzed sextants; code 3 in 18 and code 4 in 22. We concluded that periodontal disease is very severe in diabetics

  14. Prevalence of cutaneous manifestations of diabetes mellitus

    International Nuclear Information System (INIS)

    Ahmed, K.; Muhammad, Z.; Qayum, I.

    2009-01-01

    Diabetes mellitus (DM) is a clinical syndrome characterized by hyperglycaemia due to absolute or relative insulin deficiency. The aim of this study was to evaluate the frequency of skin manifestations in patients with diabetes mellitus of this area. This descriptive study was conducted in medical out patient door of District Headquarter Hospital Battgram from January 2008 to July 2008. A total of 350 diabetic (types 1 and 2) patients over 15 years of age attending the medical OPD of DHQ Hospital were examined in detail for skin manifestations of the disease. Three hundred and fifty diabetic (type-1 and type-2) patients (193 females and 157 males) enrolled in this study. Mean age of the patients was 54+-8.53 years. Duration of diabetes was between 1-12 years; 320 patients had type-2 and 30 patients had type-1 diabetes mellitus. Patients with uncontrolled disease were 327 and 23 patients showed adequate glycaemic control. Seventy-six percent of patients had cutaneous manifestations. The skin manifestations observed were: skin infections 30.9%, foot gangrene and ulcers 12.9%, pruritus 7.1%, vitiligo 5.7%, yellow skin 4.2%, diabetic dermopathy 4.2%, skin tags 3.7%, acanthosis nigricans 2.9%, eruptive xanthomas 2.6%, necrobiosis lipoidica diabeticorum 1.4%, diabetic bullae 0.6%, and pigmented purpuras in 0.3% patients. Cutaneous manifestations were quite Common in the diabetics of this area. (author)

  15. Diagnostic criteria for gestational diabetes mellitus (WS 331-2011)

    Institute of Scientific and Technical Information of China (English)

    Medical Service Specialty Standard Committee of Mi

    2012-01-01

    The criteria provide the screening and diagnosis for gestational diabetes mellitus and it should be applied to all medical institutions and health care practitioners for gestational diabetes mellitus (DM) diagnosis in China.

  16. Psychosocial determinants of type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Afzal, S.; Amin, M.K.; Ahmad, I.; Amer, H.; Shoaib, H.; Ibrahim, H.; Tayyab, M.; Hassan, M.; Javaid, M.A.; Rehman, M.A.

    2013-01-01

    Diabetes Mellitus type 2 , formerly non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes, is a metabolic disorder that is characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency1. The development of Diabetes Mellitus type 2 is associated with multiple risk factors, co-morbid medical conditions as well as psychosocial determinants. These psychosocial factors, which differ from population to population, can be identified and controlled to reduce the incidence of type 2 Diabetes Mellitus. Objective: To identify various psychosocial factors associated with type 2 Diabetes Mellitus. Design: Case-control study. Place and Duration: Diabetic clinic and Medical Units Mayo Hospital Lahore . July to December, 2012. Subjects and Methods: A population based case-control study with 1:1 case to control ratio was conducted. A total of 100 subjects (50 cases and 50 controls) having age above 35 years were recruited in the study. Selection was made on laid down criteria from patients coming to Mayo Hospital Lahore after taking consent. Interviews were conducted through a pretested questionnaire. Data was collected, compiled and analyzed through IBM SPSS version 20. Results: Out of 100 study subjects 67% were males and 33% were females. Among cases of Diabetes mellitus type 2, 64% were males, 70% in the age group 35-50 years, 96% were married, 36% were illiterates. Mean age was found 49.24, standard deviation 10.915. In bivariate analysis, Diabetes Mellitus type II was found significantly associated with Anxiety(OR: 5.348, 95% CI: 2.151-13.298) Depression(OR: 5.063, 95% CI: 1.703-15.050), High fat diet, (OR: 2.471, 95% CI: 1.100-5.547) Sedentary Lifestyle(OR: 4.529, 95% CI: 1.952-10.508) and Psychological Stress(OR:4.529, 95% CI: 1.952-10.508). However, in multivariate analysis while controlling all other risk factors, Anxiety(OR: 6.066, 95% CI: 1.918-19.191), High fat diet(OR: 3.648, 95% CI: 1

  17. Pancreatogenic diabetes mellitus: actual problems of pathogenesis and treatment

    OpenAIRE

    Rebrov А.P.; Kunitsyna М.А.; Kashkina E.I.; Arkhangelskaya Е.Е.

    2012-01-01

    We have presented the review of literature devoted to the problem of pancreatogenic diabetes mellitus. We have found up that prevalence of pancreatogenic diabetes mellitus needs to be adjusted. In analyzed literature the influence of localization of structural changes of pancreatic tissue on risk of diabetes mellitus development is studied insufficiently. In the result of our literature analysis we have detected that treatment of pancreatogenic diabetes mellitus up to date is not unified and ...

  18. Frecuencia y características clínicas de la nefropatìa incipiente en personas con diabetes mellitus tipo 2 de diagnóstico reciente Frequency and clinical characteristics of incipient neuropathy in persons recently diagnosed with diabetes mellitus type 2

    Directory of Open Access Journals (Sweden)

    Manuel E. Licea Puig

    2003-04-01

    Full Text Available El objetivo de este trabajo fue determinar la frecuencia y las características clínicas de la nefropatía diabética incipiente (NDI en personas con diabetes mellitus tipo 2 (DM2 de diagnóstico reciente, negativos en relación con los anticuerpos antislotes pancreáticos (ICA y la antidescarboxilasa del ácido glutámico (AGAD. Se estudiaron 183 personas con DM2 (ICA y AGAD negativos, atendidas en el Centro de Atención al Diabético, con la evaluación de las siguientes variables: edad, sexo, hábito de fumar, índice de masa corporal (IMC, edad al debut, tipo de tratamiento de la DM, presencia de retinopatía diabética (RD y la presión arterial, así como la glucemia en ayunas y posprandial. Se determinó ICA, AGAD, hemoglobina glucosilada (HbA1, glucemia en ayuna y postprandial 2 horas después del desayuno y del almuerzo, así como excreción urinaria de albúmina (EUA en orina de 24 horas. No se incluyó a pacientes con ND diabética clínica (EUA ³ 300 mg/L, con nefropatía no diabética, ni con otras causas o condiciones de aumento de EUA. Los sujetos se dividieron en 2 grupos: normoalbuminúricos (EUA £ 20 mg/L N = 163, y microalbuminúricos (NDI incipiente EUA > 20 a The objective of this paper was to determine the frequency and clinical characteristics of incipient diabetic nephropathy(IDN in persons with type 2 diabetes mellitus of recent diagnosis negatives for pancreatic islet cell antibodies (ICA and glutamic acid decarboxylase antibodies(AGAD. One-hundred and three persons with DM2 (negative ICA and AGAD, seen at the Diabetic Care Center, were studied and evaluated according to the following variables: age, sex, smoking, body mass index (BMI; age of onset of diabetes, type of DM treatment, presence of diabetic retinopathy (DR and blood pressure as well as glucemia at fasting and postprandial. The study determined ICA, AGAD, glycosylated hemoglobin(HbA1, glucemia at fasting and postprandial two hours after breakfast and

  19. Genetics of type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    Hansen, Lars; Pedersen, Oluf

    2005-01-01

    Throughout the last decade, molecular genetic studies of non-autoimmune diabetes mellitus have contributed significantly to our present understanding of this disease's complex aetiopathogenesis. Monogenic forms of diabetes (maturity-onset diabetes of the young, MODY) have been identified...... and classified into MODY1-6 according to the mutated genes that by being expressed in the pancreatic beta-cells confirm at the molecular level the clinical presentation of MODY as a predominantly insulin secretory deficient form of diabetes mellitus. Genomewide linkage studies of presumed polygenic type 2...... diabetic populations indicate that loci on chromosomes 1q, 5q, 8p, 10q, 12q and 20q contain susceptibility genes. Yet, so far, the only susceptibility gene, calpain-10 (CAPN10), which has been identified using genomewide linkage studies, is located on chromosome 2q37. Mutation analyses of selected...

  20. MANIFESTASI RONTGENOGRAFI DIABETES MELLITUS DI RONGGA MULUT

    Directory of Open Access Journals (Sweden)

    Trelia Boel

    2015-07-01

    Full Text Available Diabetes mellitus is a common disease, described as a systemic disease of carbohydrate metabolism caused by a realtive or absolute deficiency of insulum. This condition is characterized by hyperglyecemia, glucosuria, polyuria, polydipsia, pruritis, and weight loss. Diabetes mellitus in itself does not cause periodontal disease, however diabetes or patients with an increased blood glucose concentration (>200mg/dl tend to gave increased incidence and severity of periodontal disease. Patient with diabetics above 50 years old (3 cases radiographically can be seen as alveolar bone loss in maxilla and mandible. Alveolar bone loss is seen larger in the posterior maxilla region. The vascular alteration in diabetics may enhance the susceptibility of periodontium to become periodontitis and serve as an etiology factor in pathologic bone resorption.

  1. Postprandial hyperinsulinaemic hypoglycaemia and type 1 diabetes mellitus

    OpenAIRE

    Poon, Myra; Hussain, Khalid

    2009-01-01

    A patient with severe postprandial hyperinsulinaemic hypoglycaemia (PPHH) for 4 years developed type 1 diabetes mellitus. She had no insulin or insulin receptor antibodies but was positive for islet cell and glutamic acid decarboxylase (GAD) antibodies. PPHH prior to the onset of type 1 diabetes mellitus has not been previously described and may be a prodrome of type 1 diabetes mellitus.

  2. 76 FR 44650 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-07-26

    ...-2011-0143] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  3. 76 FR 53707 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-08-29

    ...-2011-0145] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  4. 77 FR 25227 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-04-27

    ...-2011-0383] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants...

  5. 78 FR 50486 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  6. 76 FR 79756 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-12-22

    ...-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...).\\1\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be...

  7. 78 FR 37273 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-20

    ...-2013-0016] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  8. 77 FR 75493 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-20

    ...-2012-0282] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  9. 77 FR 532 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-2011-0300] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... included in this notice. Diabetes Mellitus and Driving Experience of the Applicants The Agency established...

  10. 78 FR 26422 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ...-2013-0012] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  11. 77 FR 65929 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-31

    ...-2012-0219] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  12. 77 FR 48587 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-14

    ...-0217] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  13. 77 FR 70529 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-11-26

    ...-2012-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  14. 77 FR 75492 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-20

    ...-2012-0283] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  15. 77 FR 38383 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-27

    ...-2012-0107] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  16. 78 FR 35088 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-11

    ...-2013-0015] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... would be achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and... of diabetes mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA...

  17. 77 FR 59447 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ...-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  18. 77 FR 64585 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-22

    ...-2012-0218] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  19. 78 FR 50482 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  20. 77 FR 46791 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-06

    ...-2012-0162] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  1. 78 FR 5559 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-25

    ...-2012-0348] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  2. 78 FR 39825 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-07-02

    ...-2013-0018] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diagnosis of diabetes mellitus currently requiring insulin for control'' [49 CFR 391.41(b)(3)]. FMCSA... Congress on the Feasibility of a Program to Qualify Individuals with Insulin-Treated Diabetes Mellitus to...

  3. 76 FR 79759 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-12-22

    ...-2011-0278] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  4. 77 FR 18302 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-27

    ...-0043] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... for individual assessment of drivers with diabetes mellitus, and be consistent with the criteria...

  5. 77 FR 33264 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-05

    ...-2012-0044] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  6. 77 FR 59450 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ...-2012-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring...

  7. 77 FR 17111 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-23

    ...-0042] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  8. 76 FR 61139 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ...-2011-0192] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  9. 77 FR 29446 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-05-17

    ...-2012-0043] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the Applicants The... vehicle if that person has no established medical history or clinical diagnosis of diabetes mellitus...

  10. 78 FR 37272 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-20

    ...-2013-0017] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... achieved by complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving... mellitus currently requiring insulin for control'' (49 CFR 391.41(b)(3)). FMCSA established its diabetes...

  11. Catarata e diabetes mellitus tipo 1

    OpenAIRE

    Pizzol,Melissa Manfroi Dal; Esteves,Jorge Freita; Sccoco,Caio Augusto; Roggia,Murilo Felix; Rosa,Carolina Maurente da; Lambert,José Humberto Franco; Canani,Luís Henrique

    2008-01-01

    OBJETIVO: Avaliar a prevalência de catarata e seus fatores de risco em uma população portadora de diabetes mellitus tipo 1 (DM1). MÉTODOS: Estudo de casos e controles de um banco de dados de 181 pacientes (362 olhos) com diagnóstico de diabetes mellitus tipo 1. Os pacientes foram classificados como casos quando apresentavam diagnóstico de catarata. As variáveis estudadas foram a presença ou não de retinopatia diabética, tratamento com panfotocoagulação, presença de hipertensão arterial sistêm...

  12. Diabetes Mellitus and the Musculoskeletal System

    International Nuclear Information System (INIS)

    Monu, Johnny V.J.

    2015-01-01

    Diabetes mellitus is a metabolic disease with systemic manifestations. Occurrence is increasing worldwide from 153m to 347m from 1980 to 2011. Traditionally there are two main types: Insulin dependent or juvenile diabetes and non-insulin dependent or Maturity onset or insulin resistant diabetes. Gestational diabetes the second type of diabetes is increasingly seen in young patients and it evolves into insulin dependence. Obesity is causally related to type II diabetes. Diabetes Mellitus affects appendicular and peripheral structures more commonly – ankle and feet. Diabetes in the MSK System effects manifested as congenital problems, Peripheral neuropathy, Peripheral vasculopathy Infections and Connective tissue changes. The disease target Structures like Cardio-vascular system, Central nervous system (brain, eyes) and peripheral nerves, Reticulo-endothelial system, Kidneys and Musculoskeletal system. Osteomyelitis fractures including fragmentation of bones and disorganization of joints – neuropathic changes. Diabetic Myopathy occurs predominantly in long-standing, poorly controlled type 1 diabetics often have other vascular or end organ complications. Etiology related to microvascular disease leads to muscle ischemia and infarction eventual muscle atrophy

  13. Den kliniske betydning af gestationel diabetes mellitus

    DEFF Research Database (Denmark)

    Jensen, Dorte Møller; Beck-Nielsen, H; Westergaard, J G

    1999-01-01

    In Denmark, gestational diabetes mellitus (GDM) develops in about 2% of all pregnant women. The discussion of GDM is complicated by lack of consensus regarding screening methods, diagnosis and treatment. Observational studies indicate that untreated GDM is associated with an increased risk...... of maternal and perinatal morbidity, and that the offspring of GDM mothers tend to be at increased risk of developing diabetes and adiposity as a result of an abnormal intrauterine environment. Several follow-up studies have shown that women with previous GDM run a considerable risk of developing diabetes...... (especially type 2 diabetes) later in life. Intervention strategies for this high risk group are suggested....

  14. Den kliniske betydning af gestationel diabetes mellitus

    DEFF Research Database (Denmark)

    Jensen, Dorte Møller; Beck-Nielsen, H; Westergaard, J G

    2000-01-01

    In Denmark, gestational diabetes mellitus (GDM) develops in about 2% of all pregnant women. The discussion of GDM is complicated by lack of consensus regarding screening methods, diagnosis and treatment. Observational studies indicate that untreated GDM is associated with an increased risk...... of maternal and perinatal morbidity, and that the offspring of GDM mothers tend to be at increased risk of developing diabetes and adiposity as a result of an abnormal intrauterine environment. Several follow-up studies have shown that women with previous GDM run a considerable risk of developing diabetes...... (especially type 2 diabetes) later in life. Intervention strategies for this high risk group are suggested....

  15. Den kliniske betydning af gestationel diabetes mellitus

    DEFF Research Database (Denmark)

    Jensen, Dorte Møller; Beck-Nielsen, H; Westergaard, J G

    1999-01-01

    In Denmark, gestational diabetes mellitus (GDM) develops in about 2% of all pregnant women. The discussion of GDM is complicated by lack of consensus regarding screening methods, diagnosis and treatment. Observational studies indicate that untreated GDM is associated with an increased risk...... (especially type 2 diabetes) later in life. Intervention strategies for this high risk group are suggested....... of maternal and perinatal morbidity, and that the offspring of GDM mothers tend to be at increased risk of developing diabetes and adiposity as a result of an abnormal intrauterine environment. Several follow-up studies have shown that women with previous GDM run a considerable risk of developing diabetes...

  16. Den kliniske betydning af gestationel diabetes mellitus

    DEFF Research Database (Denmark)

    Jensen, Dorte Møller; Beck-Nielsen, H; Westergaard, J G

    2000-01-01

    In Denmark, gestational diabetes mellitus (GDM) develops in about 2% of all pregnant women. The discussion of GDM is complicated by lack of consensus regarding screening methods, diagnosis and treatment. Observational studies indicate that untreated GDM is associated with an increased risk...... (especially type 2 diabetes) later in life. Intervention strategies for this high risk group are suggested....... of maternal and perinatal morbidity, and that the offspring of GDM mothers tend to be at increased risk of developing diabetes and adiposity as a result of an abnormal intrauterine environment. Several follow-up studies have shown that women with previous GDM run a considerable risk of developing diabetes...

  17. Genetic Counseling for Diabetes Mellitus

    Science.gov (United States)

    Stein, Stephanie A.; Maloney, Kristin L.; Pollin, Toni I.

    2014-01-01

    Most diabetes is polygenic in etiology, with (type 1 diabetes, T1DM) or without (type 2 diabetes, T2DM) an autoimmune basis. Genetic counseling for diabetes generally focuses on providing empiric risk information based on family history and/or the effects of maternal hyperglycemia on pregnancy outcome. An estimated one to five percent of diabetes is monogenic in nature, e.g., maturity onset diabetes of the young (MODY), with molecular testing and etiology-based treatment available. However, recent studies show that most monogenic diabetes is misdiagnosed as T1DM or T2DM. While efforts are underway to increase the rate of diagnosis in the diabetes clinic, genetic counselors and clinical geneticists are in a prime position to identify monogenic cases through targeted questions during a family history combined with working in conjunction with diabetes professionals to diagnose and assure proper treatment and familial risk assessment for individuals with monogenic diabetes. PMID:25045596

  18. Costos directos de atención médica en pacientes con diabetes mellitus tipo 2 en México: análisis de microcosteo Direct costs of medical care for patients with type 2 diabetes mellitus in Mexico micro-costing analysis

    Directory of Open Access Journals (Sweden)

    Rosibel de los Ángeles Rodríguez Bolaños

    2010-12-01

    Full Text Available OBJETIVO: Estimar los costos directos de la atención médica a pacientes con diabetes mellitus tipo 2 (DM2 en el Instituto Mexicano del Seguro Social (IMSS. MÉTODOS: Se revisaron expedientes clínicos de 497 pacientes que ingresaron a unidades de segundo y tercer nivel de atención durante el período 2002-2004. Los costos se cuantificaron utilizando el enfoque de costeo de enfermedad (CDE desde la perspectiva del proveedor, la técnica del microcosteo y la metodología de abajo-arriba (bottom-up. Se estimaron costos promedio anuales de diagnóstico, por complicación y total de la enfermedad. RESULTADOS: El costo total anual de los pacientes con DM2 para el IMSS fue de US$452 064 988, correspondiente a 3,1% del gasto de operación. El costo promedio anual por paciente fue de US$3 193,75, correspondiendo US$2 740,34 para el paciente sin complicaciones y US$3 550,17 para el paciente con complicaciones. Los días/cama en hospitalización y en unidad de cuidados intensivos fueron los servicios con mayor costo. CONCLUSIONES: Los elevados costos en la atención médica a pacientes con DM2 y complicaciones representan una carga económica que las instituciones de salud deben considerar en su presupuesto, a fin de poder brindar un servicio de calidad, adecuado y oportuno. El empleo de la metodología de microcosteo permite un acercamiento a datos reales de utilización y manejo de la enfermedadOBJECTIVE: Estimate the direct cost of medical care incurred by the Mexican Social Security Institute (IMSS, Instituto Mexicano del Seguro Social for patients with type 2 diabetes mellitus (DM2. METHODS: The clinical files of 497 patients who were treated in secondary and tertiary medical care units in 2002-2004 were reviewed. Costs were quantified using a disease costing approach (DCA from the provider's perspective, a micro-costing technique, and a bottom-up methodology. Average annual costs by diagnosis, complication, and total cost were estimated. RESULTS

  19. Diabetes mellitus: Trends in northern India

    Directory of Open Access Journals (Sweden)

    Manish Gutch

    2014-01-01

    Full Text Available Diabetes mellitus is becoming a global health issue with more than 80% diabetics living in developing countries. India accounts for 62.4 million diabetics (2011. Indian Council of Medical Research India Diabetes Study (ICMR-INDIAB study showed highest weighted prevalence rate in the north India among all studied regions. Diabetes in north India has many peculiarities in all aspects from risk factors to control programmers. North Indians are becoming more prone for diabetes and dyslipidemia because rapid westernization of living style and diet due rapid migration to metropolitan cities for employment. North Indian diabetes is plagued with gender bias against females, poor quality of health services, myths, and lack of disease awareness compounded with small number of prevention and awareness programmers that too are immature to counteract the growing pandemic.

  20. Diabetes mellitus and upper gut motility

    Directory of Open Access Journals (Sweden)

    F. Mandolfino

    2013-01-01

    Full Text Available The aim of the study is to detect the presence of esophageal motor disorders in type I and II diabetic patients, and to establish whether there is any difference between patients with and without neuropathy. 118 diabetics patients (34 type I and 84 type II were investigated by water-perfused stationary esophageal manometry. Data were correlated with the presence of peripheral neurophaty. As a result 71% of patients affected by peripheral neuropathy showed manometric abnormalities against the 37% of the patients without neuropathy. Our experience has shown that patients with diabetes mellitus frequently present esophageal symptoms and manometric abnormalities. Manometric study of the esophagus has to be considered a useful investigative tool to manage and monitorize the gastrointestinal abnormalities in patients affected by diabetes mellitus.

  1. Manifestações musculoesqueléticas em diabetes mellitus Musculoskeletal disorders in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Marilia Barreto Gameiro Silva

    2012-08-01

    Full Text Available O diabetes mellitus está associado a uma grande variedade de manifestações musculoesqueléticas. Muitas delas são subclínicas e correlacionadas com tempo de evolução e controle inadequado da doença, e devem ser reconhecidas e adequadamente tratadas, pois sua abordagem melhora a qualidade de vida desses pacientes. Nesta revisão são discutidas as principais manifestações musculoesqueléticas encontradas em diabetes mellitus.Diabetes mellitus is associated with a great variety of musculoskeletal manifestations, many of which are subclinical and correlated with disease duration and its inadequate control. They should be recognized and treated properly, because their management improves the patients' quality of life. This review discusses the major musculoskeletal manifestations found in diabetes mellitus.

  2. Disturbances of Haemostasis in Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Mohamed A. Fattah

    2004-01-01

    Full Text Available Diabetes mellitus is associated with disturbances in haemostasis that could contribute to the development of thrombotic complications.The present study was undertaken to determine the behavior of coagulation variables and fibrinolytic system in diabetes mellitus. Forty five diabetic patients and forty five matched controls were evaluated by doing the following haemostatic parameter, prothrombin time, partial thromboplastin time, thrombin time, coagulation factors assay II, VII, IX, & plasma fibrinogen, ADP-induced platelet aggregation, protein C, a2- antiplasmin, PAI and FDPs. Generally diabetic patients have high levels of fibrinogen, a2- antiplasmin, & PAI and lower level of protein C. Other haemostatic parameters did not show statistically significant difference between diabetic patients and control group. Significantally elevated levels of PAI, a2- antiplasmin together with low protein C level in diabetic patients may result in the disturbance of haemostatic balance favoring thrombotic events. Conclusion: High levels of plasma fibrinogen, a2A- antiplasmin with low plasma protein C activity could lead to a prothrombotic tendency in insulin dependent diabetic patients. Moreover, in non-insulin dependent diabetic patients, the above mentioned parameters together with high levels of ADP-induced platelet aggregation and plasminogen activator inhibitor may increase the risk of thrombotic complications. Obesity can be considered as an additional risk factor for development of thrombosis in diabetic patients.

  3. Cutaneous Manifestations of Diabetes Mellitus: A Review.

    Science.gov (United States)

    Lima, Ana Luiza; Illing, Tanja; Schliemann, Sibylle; Elsner, Peter

    2017-08-01

    Diabetes mellitus is a widespread endocrine disease with severe impact on health systems worldwide. Increased serum glucose causes damage to a wide range of cell types, including endothelial cells, neurons, and renal cells, but also keratinocytes and fibroblasts. Skin disorders can be found in about one third of all people with diabetes and frequently occur before the diagnosis, thus playing an important role in the initial recognition of underlying disease. Noninfectious as well as infectious diseases have been described as dermatologic manifestations of diabetes mellitus. Moreover, diabetic neuropathy and angiopathy may also affect the skin. Pruritus, necrobiosis lipoidica, scleredema adultorum of Buschke, and granuloma annulare are examples of frequent noninfectious skin diseases. Bacterial and fungal skin infections are more frequent in people with diabetes. Diabetic neuropathy and angiopathy are responsible for diabetic foot syndrome and diabetic dermopathy. Furthermore, antidiabetic therapies may provoke dermatologic adverse events. Treatment with insulin may evoke local reactions like lipohypertrophy, lipoatrophy and both instant and delayed type allergy. Erythema multiforme, leukocytoclastic vasculitis, drug eruptions, and photosensitivity have been described as adverse reactions to oral antidiabetics. The identification of lesions may be crucial for the first diagnosis and for proper therapy of diabetes.

  4. [Evaluation of nopal capsules in diabetes mellitus].

    Science.gov (United States)

    Frati Munari, A C; Vera Lastra, O; Ariza Andraca, C R

    1992-01-01

    To find out if commercial capsules with dried nopal (prickle-pear cactus, Opuntia ficus indica may have a role in the management of diabetes mellitus, three experiments were performed: 30 capsules where given in fasting condition to 10 diabetic subjects and serum glucose was measured through out 3 hours; a control test was performed with 30 placebo capsules. OGTT with previous intake of 30 nopal or placebo capsules was performed in ten healthy individuals. In a crossover and single blinded study 14 diabetic patients withdrew the oral hypoglycemic treatment and received 10 nopal or placebo capsules t.i.d. during one week; serum glucose, cholesterol and tryglycerides levels were measured before and after each one-week period. Five healthy subjects were also studied in the same fashion. Opuntia capsules did not show acute hypoglycemic effect and did not influence OGTT. In diabetic patients serum glucose, cholesterol and tryglycerides levels did not change with Opuntia, but they increased with placebo (P nopal, while cholesterol and triglycerides decreased (P < 0.01 vs. placebo). The intake of 30 Opuntia capsules daily in patients with diabetes mellitus had a discrete beneficial effect on glucose and cholesterol. However this dose is unpractical and at present it is not recommended in the management of diabetes mellitus.

  5. Type 2 diabetes mellitus as a disorder of galanin resistance.

    Science.gov (United States)

    Fang, Penghua; Shi, Mingyi; Zhu, Yan; Bo, Ping; Zhang, Zhenwen

    2016-01-01

    The increasing prevalence of type 2 diabetes mellitus with its high morbidity and mortality becomes an important health problem. The multifactorial etiology of type 2 diabetes mellitus is relative to many gene and molecule alterations, and increased insulin resistance. Besides these, however, there are still other predisposing and risk factors accounting for type 2 diabetes mellitus not to be identified and recognized. Emerging evidence indicated that defects in galanin function played a crucial role in development of type 2 diabetes mellitus. Galanin homeostasis is tightly relative to insulin resistance and is regulated by blood glucose. Hyperglycemia, hyperinsulinism, enhanced plasma galanin levels and decreased galanin receptor activities are some of the characters of type 2 diabetes mellitus. The discrepancy between high insulin level and low glucose handling is named as insulin resistance. Similarly, the discrepancy between high galanin level and low glucose handling may be denominated as galanin resistance too. In this review, the characteristic milestones of type 2 diabetes mellitus were condensed as two analogical conceptual models, obesity-hyper-insulin-insulin resistance-type 2 diabetes mellitus and obesity-hyper-galanin-galanin resistance-type 2 diabetes mellitus. Both galanin resistance and insulin resistance are correlative with each other. Conceptualizing the etiology of type 2 diabetes mellitus as a disorder of galanin resistance may inspire a new concept to deepen our knowledge about pathogenesis of type 2 diabetes mellitus, eventually leading to novel preventive and therapeutic interventions for type 2 diabetes mellitus. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Undiagnosed diabetes mellitus in community-acquired pneumonia

    DEFF Research Database (Denmark)

    Jensen, Andreas Vestergaard; Faurholt-Jepsen, Daniel; Egelund, Gertrud Baunbæk

    2017-01-01

    Background: Diabetes mellitus is an important risk factor for community-acquired pneumonia, whereas the prevalence of undiagnosed diabetes mellitus and prediabetes in patients with community-acquired pneumonia is largely unknown. We aimed to determine the prevalence of prediabetes, undiagnosed......-acquired pneumonia included in the German Community-Acquired Pneumonia Competence Network (CAPNETZ) study between 2007 and 2014. The prevalence of undiagnosed diabetes mellitus and prediabetes was estimated based on hemoglobin A1c measurements. Logistic regression was used to assess risk factors for undiagnosed...... diabetes mellitus. Results: Fifteen percent of patients had known diabetes mellitus. Among patients without known diabetes mellitus, 5.0% had undiagnosed diabetes mellitus and 37.5% had prediabetes. Male sex (odds ratio [OR], 2.45 [95% confidence interval {CI}, 1.35-4.45]), body mass index ≥25 kg/m2 (OR, 2...

  7. Kost, diabetes mellitus og parodontal inflammation

    DEFF Research Database (Denmark)

    Damgaard, Christian; Holmstrup, Palle

    2016-01-01

    Nærværende artikel præsenterer en oversigt over den foreliggende viden om kostens betydning for diabetes mellitus (DM) og parodontal inflammation. Der er i vekslende grad dokumentation for sammenhænge mellem kost, DM og marginal parodontitis (MP). Med baggrund i forøget viden om kostens betydning...

  8. Glucose-homeostase bij diabetes mellitus

    NARCIS (Netherlands)

    Oosten, Hessel Rienk

    1988-01-01

    In dit proefschrift worden enige aspecten van de glucosehomeostase bij type I (insuline afhankelijke) diabetes mellitus behandeld. Deze aspecten betreffen onder meer: het effect van verschillende glucosespiegels op de glucosebehoefte bij lage (±10 mE/m²/min) en verhoogde (30 mE/m²/min)

  9. Kost, diabetes mellitus og parodontal inflammation

    DEFF Research Database (Denmark)

    Damgaard, Christian; Holmstrup, Palle

    2017-01-01

    Nærværende artikel præsenterer en oversigt over den foreliggende viden om kostens betydning for diabetes mellitus (DM) og parodontal inflammation. Der er i vekslende grad dokumentation for sammenhænge mellem kost, DM og marginal parodontitis (MP). Med baggrund i forøget viden om kostens betydning...

  10. Diabetes mellitus in pregnancy, still changing

    African Journals Online (AJOL)

    gestational and type 2 diabetes mellitus, respectively, were overweight or obese. Chronic hypertension was ... in non-pregnant women, fasting levels of serum glucose are decreased, ... second practical option, whereby the patient's breakfast is brought to ... continuous variables and nominal variables, while the chi-square.

  11. Risk factors for feline diabetes mellitus

    NARCIS (Netherlands)

    Slingerland, L.I.|info:eu-repo/dai/nl/304830917

    2008-01-01

    The chapters of Part I of the thesis describe the development of techniques that can be used in the assessment of risk factors for the development of diabetes mellitus (DM) in cats. The hyperglycemic glucose clamp (HGC) was developed for use in conscious cats, equipped with arterial catheters for

  12. Serum markers for type II diabetes mellitus

    Science.gov (United States)

    Metz, Thomas O; Qian, Wei-Jun; Jacobs, Jon M; Polpitiya, Ashoka D; Camp, II, David G; Smith, Richard D

    2014-03-18

    A method for identifying persons with increased risk of developing type 2 diabetes mellitus utilizing selected biomarkers described hereafter either alone or in combination. The present invention allows for broad based, reliable, screening of large population bases and provides other advantages, including the formulation of effective strategies for characterizing, archiving, and contrasting data from multiple sample types under varying conditions.

  13. an alternative therapy for gestational diabetes mellitus

    African Journals Online (AJOL)

    Toxic effects of glibenclamide in fetuses of normoglycemic rats: an alternative therapy for gestational diabetes mellitus. ... However, GLIB animals presented a light brownish precipitate into the center-lobular veins and in the liver parenchyma among the hepatocytes. These results indicated a possible passage of the drug ...

  14. Diabetes mellitus, pulmonary tuberculosis and chronic calcific ...

    African Journals Online (AJOL)

    The prevalence of chronic calcific pancreatitis (CCP) was determined in 25 successive patients with both diabetes mellitus and newly diagnosed pulmonary tuberculosis. Twenty patients (80%) were alcoholics and all were black. Of these, 9 (45%) had CCP. In only 3 of these 9 patients was the history compatible with the ...

  15. Misconceptions about diabetes mellitus among adult male ...

    African Journals Online (AJOL)

    Background: Diabetes mellitus (DM) is a major public health problem in Saudi Arabia. Its prevalence is on the increase, being as high as 23.7% among adult citizens. Misconceptions and wrong beliefs regarding DM and its management among those attending primary health care centres (PHCCs) can result in poor control, ...

  16. Diabetes mellitus, pulmonary tuberculosis and chronic calcific ...

    African Journals Online (AJOL)

    The prevalence of chronic calcific pancreatitis (CCP) was determined in 25 successive patients with both diabetes mellitus and newly diagnosed pulmonary tuberculosis. Twenty patients (80%) were alcoholics and all were black. Of these, 9. (45%) had CCP. In only 3 of these 9 patients was the history compatible with the ...

  17. Costos económicos en el tratamiento farmacológico del paciente con diabetes mellitus tipo 2. Estudio de pacientes en consulta externa de medicina interna de un hospital de segundo nivel de la Ciudad de México

    Directory of Open Access Journals (Sweden)

    Juan Pablo Ramírez-Hinojosa

    2017-01-01

    Full Text Available La diabetes mellitus tipo 2 (DM2 es considerada un problema de salud pública global. Es la primera causa de morbilidad-mortalidad en el país. Representa una enfermedad de alto costo para los sistemas de salud, con un gasto de 370 billones de dólares al año, que se estima alcanzará los 490 billones de dólares para 2030...

  18. Bartter's Syndrome with Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Ting-Ting See

    2009-02-01

    Full Text Available We report a rare case of Bartter's syndrome in a 35-year-old woman with type 2 diabetes mellitus. The patient presented with leg weakness, fatigue, polyuria and polydipsia. Hypokalemia, metabolic alkalosis, and high renin and aldosterone concentrations were present, but the patient was normotensive. Gitelman's syndrome was excluded because of the presence of hypercalciuria, secondary hyperparathyroidism and bilateral nephrocalcinosis. The patient's condition improved upon administration of a prostaglandin synthetase inhibitor (acemetacin, oral potassium chloride and potassium-sparing diuretics. Five months later, the patient discontinued acemetacin because of epigastric discomfort; at the same time, severe hypokalemia and hyperglycemia developed. Glucagon stimulation and water deprivation tests were performed. Type 2 diabetes mellitus with nephrogenic diabetes insipidus was diagnosed. To avoid further gastrointestinal complications, the patient was treated with celecoxib, a selective cyclooxygenase 2 inhibitor. This case serves as a reminder that Bartter's syndrome is associated with various metabolic derangements including nephrogenic diabetes insipidus, nephrocalcinosis and diabetes mellitus. When treating Bartter's syndrome, it is also prudent to remember that the long-term use of nonsteroidal anti-inflammatory drugs and potassium-sparing diuretics may result in serious adverse reactions.

  19. [Nasal mucosa in patients with diabetes mellitus].

    Science.gov (United States)

    Müller, Maciej; Betlejewski, Stanisław

    2003-01-01

    Diabetes mellitus is the most common endocrinologic disease all over the world. 150 million people suffer from this disease, in Poland about 2 million. The disease on the basis of the onset and pathophysiology may be divided into type I and type II. Pathophysiologic changes include diabetic microangiopathy, macroangiopathy and neuropathy. The most common presentations in head and neck are otitis externa, hypoacusis, vertigo, disequilibrium, xerostomia, dysphagia, fungal and recurrent infections. The changes in nasal mucosa are not very well known. Only few papers concerned the problem. The main complaints of patients regarding the nose are xeromycteria, hyposmia and various degree of decreased patency of the nose. Chronic atrophic rhinitis, septal perforation, ulceration of nasal mucosa, alar necrosis, symptoms of staphylococcal or fungal infection can be found during otolaryngologic examination. The treatment in this group of patients should consist of systemic therapy of diabetes mellitus and on the other hand focal therapy with the use of a solution to moisten the nasal mucosa.

  20. Osteoporosis and diabetes mellitus: a modern viewpoint

    Directory of Open Access Journals (Sweden)

    Natalya Alexandrovna Molitvoslovova

    2013-03-01

    Full Text Available The interrelationship between diabetes mellitus (DM and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM, ? or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterioration of bone tissue ?quality?. Current article discusses various mechanisms of bone damaging in DM, as well as possible causes for difference in the severity of bone disorders, known between the two types of DM. Regarding higher risk of foot fracture in patients with DM, we specifically address distal polyneuropathy as a plausible factor for bone tissue deterioration.

  1. Mortality patterns among type 2 diabetes mellitus patients in Ilorin ...

    African Journals Online (AJOL)

    2010-01-15

    Jan 15, 2010 ... Keywords: causes of death; longevity; type 2 diabetes; Nigeria. Introduction. The incidence and prevalence of diabetes mellitus (DM) has continued ... accounted for the majority of deaths from diabetic ketoacidosis (DKA).

  2. 78 FR 76399 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0185] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 37 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from [[Page 76400

  3. Contraception for Women with Diabetes Mellitus

    DEFF Research Database (Denmark)

    Damm, P.; Mathiesen, E.; Clausen, T.D.

    2005-01-01

    Planned pregnancy is mandatory in women with diabetes, and their need for contraception is essential. Basically, the same methods can be used as in women without diabetes, but a number of specific conditions have to be considered when guiding these women, as we discuss in this review. Unfortunately......, the field is limited in studies in certain areas, especially considering contraception for women with type 1 diabetes and late diabetic complications and women with type 2 diabetes. Thus, in the real clinical world, the choice of contraceptive often will be a kind of compromise, balancing pro and cons...

  4. Contraception for women with diabetes mellitus

    DEFF Research Database (Denmark)

    Damm, Peter; Mathiesen, Elisabeth; Clausen, Tine Dalsgaard

    2005-01-01

    Planned pregnancy is mandatory in women with diabetes, and their need for contraception is essential. Basically, the same methods can be used as in women without diabetes, but a number of specific conditions have to be considered when guiding these women, as we discuss in this review. Unfortunately......, the field is limited in studies in certain areas, especially considering contraception for women with type 1 diabetes and late diabetic complications and women with type 2 diabetes. Thus, in the real clinical world, the choice of contraceptive often will be a kind of compromise, balancing pro and cons...

  5. Relation between diabetes mellitus and male fertility

    Directory of Open Access Journals (Sweden)

    Andy Petroianu

    2009-12-01

    Full Text Available Objective: The objective of the present study was to verify if there is any relation between diabetes mellitus and male infertility. Methods: the spermograms of 43 non-diabetic subjects and 12 diabetic patients (type 1 and 2 aged 20-60 years were compared. Spermiological findings in diabetic patients were compared with those of normal individuals of the same age. Serum testosterone, prolactin, follicle-stimulant hormone, luteinizing hormone, glucose and glycosilated hemoglobin were assayed in diabetic patients. Rresults: Six diabetic patients (four type 1 and two type 2 presented chronic complications attributed to neuropathy and vascular insufficiency. No difference was observed in the semen characteristics (odor, color, viscosity and pH between the control group and the diabetic patients. There were no differences between seminal concentrations and percentage of motile spermatozoa during the first hour of observation in the two groups (p < 0.05. Impotence was reported by four diabetic patients (33.3%. Erectile failure was associated with diabetic microangiopathy and neuropathy. There were no controls with impotence. No significant hormonal changes were found in the diabetic patients. Cconclusions: The present results suggest that neuropathy and vascular insufficiency  may be  implicated in sexual dysfunction in type 1 and 2 diabetic patients, without significantly affecting the hypothalamic-pituitary-gonadal axis.

  6. Gestational Diabetes Mellitus and Future Cardiovascular Risk: An Update

    OpenAIRE

    Burlina, S.; Dalfr?, M. G.; Chilelli, N. C.; Lapolla, A.

    2016-01-01

    The prevalence of gestational diabetes mellitus is increasing in parallel with the rising prevalence of type 2 diabetes and obesity around the world. Current evidence strongly suggests that women who have had gestational diabetes mellitus are at greater risk of cardiovascular disease later in life. Given the growing prevalence of gestational diabetes mellitus, it is important to identify appropriate reliable markers of cardiovascular disease and specific treatment strategies capable of contai...

  7. Musculoskeletal manifestations of diabetes mellitus.

    Science.gov (United States)

    Merashli, M; Chowdhury, T A; Jawad, A S M

    2015-11-01

    The prevalence of Type 1 and Type 2 diabetes are increasing significantly worldwide. Whilst vascular complications of diabetes are well recognized, and account for principle mortality and morbidity from the condition, musculoskeletal manifestations of diabetes are common and whilst not life threatening, are an important cause of morbidity, pain and disability. Joints affected by diabetes include peripheral joints and the axial skeleton. Charcot neuroarthropathy is an important cause of deformity and amputation associated with peripheral neuropathy. A number of fibrosing conditions of the hands and shoulder are recognized, including carpal tunnel syndrome, adhesive capsulitis, tenosynovitis and limited joint mobility. People with diabetes are more prone to gout and osteoporosis. Management of these conditions requires early recognition and close liaison between diabetes and rheumatology specialists. © The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  8. Autonomic Neuropathy in Diabetes Mellitus

    OpenAIRE

    Verrotti, Alberto; Prezioso, Giovanni; Scattoni, Raffaella; Chiarelli, Francesco

    2014-01-01

    Diabetic autonomic neuropathy (DAN) is a serious and common complication of diabetes, often overlooked and misdiagnosed. It is a systemic-wide disorder that may be asymptomatic in the early stages. The most studied and clinically important form of DAN is cardiovascular autonomic neuropathy defined as the impairment of autonomic control of the cardiovascular system in patients with diabetes after exclusion of other causes. The reported prevalence of DAN varies widely depending on inconsistent ...

  9. Plasma Renin Activity in Diabetes Mellitus

    International Nuclear Information System (INIS)

    Pyo, Heui Jung; Park Jung Sik; Kim, Sung Kwon; Choi, Kang Won; Lee, Jung Sang; Lee, Mun Ho

    1979-01-01

    To evaluate the renin-angiotensin-aldosterone system in diabetes mellitus, basal plasma renin activity (PRA) and its response to intravenous furosemide were determined in 40 diabetic subjects. The diabetics were divided into 4 groups according to the presence of nephropathy and/or hypertension. Uncomplicated diabetics (Group I) were taken as control group and the results of the other groups were compared to this group. In diabetics with nephropathy alone (Group II), and with nephropathy and hypertension (Group III), basal PRA values were 0.63±0.59 ng/ml/hr., and 0.79±0.62 ng/ml/hr., respectively, both significantly lower than control group. (1.53±1.09 ng/ml/hr.). (p<0.05) In both of the above groups, the responses to intravenous furosemide tended to be blunted. On the other hand, in diabetics, with hypertension only (Group IV), the basal and stimulated PRA were not significantly different from control. Above results suggests that nephropathy may be one of the factors which suppress renin activity in diabetes mellitus

  10. Plasma Renin Activity in Diabetes Mellitus

    Energy Technology Data Exchange (ETDEWEB)

    Pyo, Heui Jung; Sik, Park Jung; Kim, Sung Kwon; Choi, Kang Won; Lee, Jung Sang; Lee, Mun Ho [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1979-03-15

    To evaluate the renin-angiotensin-aldosterone system in diabetes mellitus, basal plasma renin activity (PRA) and its response to intravenous furosemide were determined in 40 diabetic subjects. The diabetics were divided into 4 groups according to the presence of nephropathy and/or hypertension. Uncomplicated diabetics (Group I) were taken as control group and the results of the other groups were compared to this group. In diabetics with nephropathy alone (Group II), and with nephropathy and hypertension (Group III), basal PRA values were 0.63+-0.59 ng/ml/hr., and 0.79+-0.62 ng/ml/hr., respectively, both significantly lower than control group. (1.53+-1.09 ng/ml/hr.). (p<0.05) In both of the above groups, the responses to intravenous furosemide tended to be blunted. On the other hand, in diabetics, with hypertension only (Group IV), the basal and stimulated PRA were not significantly different from control. Above results suggests that nephropathy may be one of the factors which suppress renin activity in diabetes mellitus

  11. Diagnosis and treatment of diabetes mellitus in chronic pancreatitis

    OpenAIRE

    Ewald, Nils; Hardt, Philip D

    2013-01-01

    Diabetes secondary to pancreatic diseases is commonly referred to as pancreatogenic diabetes or type 3c diabetes mellitus. It is a clinically relevant condition with a prevalence of 5%-10% among all diabetic subjects in Western populations. In nearly 80% of all type 3c diabetes mellitus cases, chronic pancreatitis seems to be the underlying disease. The prevalence and clinical importance of diabetes secondary to chronic pancreatitis has certainly been underestimated and underappreciated so fa...

  12. Risikostratificering af patienter med diabetes mellitus

    DEFF Research Database (Denmark)

    Qvist, Peter; Glintborg, Dorte; Andries, Alin

    2008-01-01

    with diabetes mellitus. MATERIAL AND METHODS: We included patients with diabetes from the catchment areas of four diabetes out-patient clinics in southern Denmark. Patients were risk-stratified to 3 follow-up levels (level 1 - follow-up only by their GP, level 2 - intensified follow-up by GP and/or shared care...... schemes, level 3 - follow-up only in out-patient clinics). The results were subsequently compared with the patients' actual follow-up status. RESULTS: A total of 647 patients (563 type 2 diabetes and 84 type 1 diabetes) were included from 15 GPs. Among these, 139 were stratified to level 1, 409 to level 2...

  13. Pancreatic scintigraphy in diabetes mellitus

    International Nuclear Information System (INIS)

    Shio, Hiroshi; Ueki, Jyuichi; Nomura, Kozi; Nakamura, Yoshifumi

    1983-01-01

    Pancreatic scintigraphy was performed on 67 diabetic patients (42 males and 25 females) in order to study exocrine pancreatic functions in primary diabetes. Relationships between visualization and the onset age, sex, morbid period, presence or absence of retinitis, good or poor control of blood glucose control and the therapeutic modality of diabetes were examined. Abnormality was detected in 34 cases (50.7%), being frequent among male patients in their 50s. The more serious the diabetes, i.e., with a longer morbid period, poorer blood glucose control and worse retinitis, the higher was the frequency of abnormality in pancreatic visualization. The frequency of abnormality was high in association with insulin treatment, oral tablets and single dietary treatment in that order. The more severe the hypoinsulinism, the higher was the frequency of abnormality. This technique can be used as a screening means for exocrine pancreatic function tests on diabetics. (Chiba, N.)

  14. Optimizing postpartum care for the patient with gestational diabetes mellitus.

    Science.gov (United States)

    Martinez, Noelle G; Niznik, Charlotte M; Yee, Lynn M

    2017-09-01

    Gestational diabetes mellitus poses well-established risks to both the mother and infant. As >50% of women with gestational diabetes mellitus will develop type 2 diabetes mellitus in their lifetime, performing postpartum oral glucose tolerance testing is paramount to initiation of appropriate lifestyle interventions and pharmacologic therapy. Nonetheless, test completion among women with gestational diabetes mellitus is estimated to be diabetes mellitus. Based on existing evidence, we propose best practices for the postpartum care of women with gestational diabetes mellitus: (1) enhanced patient support for identifying long-term health care providers, (2) patient-centered medical home utilization when possible, (3) patient and provider test reminders, and (4) formalized obstetrician-primary care provider hand offs using the Situation Background Assessment Recommendation (SBAR) mnemonic. These strategies deserve future investigation to solidify a multilevel approach for identifying and preventing the continuum of diabetes. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Statins and risk of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Richard Tjan

    2015-12-01

    Full Text Available Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA reductase, which reduces HMG-CoA to mevalonate, the precursor of cholesterol via squalene. Inhibition of HMG-CoA reductase results in a decrease in cholesterol production. Since 1987, when the United States Federal Drug Administration (FDA approved lovastatin for clinical use,(1 statins have been widely used for secondary prevention of cardiovascular disease, particularly coronary heart disease (CHD, which is associated with high levels of low-density lipoprotein (LDL cholesterol. Statins are also used in type 2 diabetes mellitus, since this carries a high risk of CHD. Statins have several adverse effects, to which must now be added new onset diabetes. In 2012 the FDA issued a warning about the risk of newly developed diabetes mellitus in older persons, such that statin labels now include information on glycemic effects, including diabetes and increases in hemoglobin A1c or fasting plasma glucose.(2 According to the results of a recent meta-analysis involving 13,966 40+-year patients newly treated with statins between 1 January 1977 and 31 March 2011, a moderate but significant increase was found in the risk of new onset diabetes within the first two years of using regular higher potency statins (rosuvastatin >10 mg, atorvastatin >20 mg, and simvastatin >40 mg, compared with lower potency drugs. Therefore these investigators caution clinicians regarding the use of higher potency statins in secondary prevention of cardiovascular disease.(2 The use of a new drug carries a “built-in time-bomb”, because nothing is known about its side effects, except for those revealed by animal tests and limited clinical trials. Even a multicenter clinical trial cannot be expected to reveal all possible adverse reactions associated with a new drug. As an illustration, in patients without diabetes mellitus, more than 345 000 cases were needed to detect an increase in fasting

  16. Prevención de diabetes mellitus 2

    OpenAIRE

    R. Verner Codoceo, Dr.

    2010-01-01

    La posibilidad de prevenir la Diabetes Mellitus 2 (DM2) se conoce desde hace décadas. Múltiples estudios epidemiológicos han comprobado que los cambios de estilo de vida tienen resultados favorables con costos menores que la propia enfermedad o terapia farmacológica, sin embargo no se ha logrado repetir estos resultados en la población general. Estudios de intervención farmacológica han logrado resultados similares, pero no existe consenso en el uso de ellos, en forma masiva, en etapa pre-dia...

  17. Nutrición en la Diabetes Mellitus 2

    OpenAIRE

    González González, Isabel

    2014-01-01

    La Diabetes Mellitus (DM), junto con la obesidad, es considerada como uno de los mayores problemas a nivel mundial. Se caracteriza por una alteración en la producción de insulina y una elevación en los niveles plasmáticos de glucosa. Dicha alteración, si es por déficit absoluto en la producción se conoce como DM tipo 1 o insulinodependiente. Si la alteración se refiere a un déficit relativo en la producción, hablamos de DM tipo 2. En otras ocasiones existe resistencia a la insulina. Los altos...

  18. Vitamins and Type 2 Diabetes Mellitus

    Science.gov (United States)

    Valdés-Ramos, Roxana; Ana Laura, Guadarrama-López; Elina, Martínez-Carrillo Beatriz; Donají, Benítez-Arciniega Alejandra

    2015-01-01

    The present review evaluates the relationship between type 2 diabetes mellitus and individual or combined vitamins. Antioxidant vitamins A, C and E are found decreased in diabetic subjects, possibly due to an increased need to control the excessive oxidative stress produced by abnormalities in glucose metabolism. On the other hand, retinol binding protein exerts a modulating effect, as it has adipokine functions. With respect to the B group vitamins, thiamin, pyridoxine and biotin have been found decreased but the mechanisms are not clear, however supplementation has shown some improvement of the metabolic control in diabetic patients. The absorption of folic acid and vitamin B12 is importantly decreased by the prolongued use of metformin, which is the first choice drug in uncomplicated diabetes, thus these two nutrients have been found deficient in the disease and most probably need to be supplemented regularly. On the other hand, vitamin D is considered a risk factor for the development of diabetes as well as its complications, particularly cardiovascular ones. Although some studies have found an association of vitamin K intake with glucose metabolism further research is needed. Studies on the use of multivitamin supplements have shown unconclusive results. After reviewing the evidence, no real recommendation on the use of vitamin supplements in type 2 diabetes mellitus can be issued, however patients using metformin during prolongued periods may need folic acid and vitamin B12. PMID:25388747

  19. Gait parameters in patients with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Cristina Elena Prado Teles Fregonesi

    2010-02-01

    Full Text Available Diabetes mellitus is a chronic disease that results in sensorimotor alterations. These changes affect balance and walking and predispose affected patients to falls. The aim of this review was to identify studies in the recent literature that assess gait parameters and aspects involved in walking. The MEDLINE, SciELO, LILACS and PEDro databases were searched using the following combination of keywords: diabetic neuropathies x gait; diabetes mellitus x gait, and diabetic foot x gait. After the application of selection criteria, 15 articles were retrieved, summarized, discussed, and are included in this review. Diabetic neuropathy was found to lead to deficits in step amplitude, gait velocity and gait cadence on flat surfaces, without sudden changes in direction or stops, and to balance and coordination deficits on inclined and uneven terrain. Diabetic neuropathies also increase plantar pressure rates and lead to difficulties in the terminal stance phase and pre-swing phase due to changes in triceps surae activation. Thus, the next initial contact occurs in an inadequate manner, with the forefoot and without absorption of shocks.

  20. Xantomas eruptivos asociados a diabetes mellitus tipo II e hipertrigliceridemia: reporte de un caso

    OpenAIRE

    Victoria Bárzaga, Héctor Oscar; Ramos Cabrera, Asmell; Lazo Sánchez, Laura

    2009-01-01

    Se reporta el caso de un hombre de raza blanca, 37 años de edad, hijo de madre con diabetes mellitus tipo 1, con antecedentes patológicos personales de padecer de obesidad exógena desde aproximadamente cinco años. Comenzó a presentar de forma diseminada una erupción papulosa de color amarillento, que se diagnosticó clínicamente e histológicamente como xantomas eruptivos asociados a diabetes mellitus tipo 2 de debut e hipertrigliceridemia. Se describen las generalidades de los xantomas eruptiv...

  1. Alteraciones de la hemostasia en la diabetes mellitus Alterations of hemostasis in the diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Patricia Caunedo Almagro

    2005-04-01

    Full Text Available La diabetes mellitus (DM se clasifica en 2 tipos de acuerdo con su patogénesis: la tipo 1 representa menos del 10 % del total de pacientes, la DM tipo 2 es más común dentro de la población de pacientes diabéticos. Se han encontrado múltiples alteraciones de la hemostasia en los pacientes con este padecimiento. Estudios realizados en plaquetas, coagulación sanguínea y fibrinólisis han permitido asegurar que estos trastornos son posiblemente un factor importante en el estado pretrombótico que presentan estos enfermos. Las investigaciones en las plaquetas han demostrado una hiperreactividad plaquetaria, un aumento de la actividad procoagulante de las plaquetas. Por otra parte, la mayoría de los autores coinciden en la actualidad en que la DM es un estado de hipercoagulabilidad,lo cual se basa en numerosas investigaciones sobre la enfermedad y el mecanismo de la coagulación que demuestran el aumento del fibrinógeno, factor VII y factor von Willebrand, así como de los marcadores de activación de este sistema. Además, se han demostrado alteraciones en el sistema fibrinolítico, como el aumento del inhibidor del activador del plasminógeno y del inhibidor de la fibrinólisis activado por trombina. En este trabajo se presentan algunos mecanismos que pudieran explicar las alteraciones en la hemostasia que posiblemente contribuyan al desarrollo de complicaciones trombóticas que se presentan en estos pacientes.Diabetes mellitus is classified into 2 types according to its pathogenesis: type 1 accounts for less than 10 % of the total of patients, whereas type 2 is the most common in the population of diabetic patients. Multiple alterations of hemostasis have been found among the patients suffering from this disease. The studies conducted in platelets, blood coagulation and fibrinolysis have allowed to assert that these disorders are probably an important factor in the prethrombotic state of these patients. The investigations carried out with

  2. Association between central diabetes insipidus and type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Claudia Palumbo

    2018-04-01

    Full Text Available Central diabetes insipidus is a rare disease of the hypothalamus and neurohypophysis. It is very unusually found in the adult with type 2 diabetes mellitus. It is manifested by a polydipsic polyuric syndrome, which must be distinguished from the poorly controlled type 2 diabetes mellitus. Given the similarity of both entities and the unusual nature of their coexistence, their suspicion is difficult. The case of a 72-year-old male with type 2 diabetes mellitus with poor insulin control (fasting hyperglycemia greater than 180 mg/dl who had a long-standing polyuric syndrome is here presented. Hypernatremia and plasma osmolality elevated together with a low urinary osmolality led to the suspicion of diabetes insipidus, which was subsequently confirmed by the dehydration test and the administration of desmopressin sc. With 61% increase in the calculated urinary osmolarity one hour post desmopressin s.c., diabetes insipidus of central type was diagnosed. Nuclear Magnetic Resonance showed a bright spot with normal neurohypophysis, contributing to the diagnosis of the idiopathic form.

  3. [Association between central diabetes insipidus and type 2 diabetes mellitus].

    Science.gov (United States)

    Palumbo, Claudia; Nicolaci, Nora; La Manna, Andrés A; Branek, Natalia; Pissano, María N

    2018-01-01

    Central diabetes insipidus is a rare disease of the hypothalamus and neurohypophysis. It is very unusually found in the adult with type 2 diabetes mellitus. It is manifested by a polydipsic polyuric syndrome, which must be distinguished from the poorly controlled type 2 diabetes mellitus. Given the similarity of both entities and the unusual nature of their coexistence, their suspicion is difficult. The case of a 72-year-old male with type 2 diabetes mellitus with poor insulin control (fasting hyperglycemia greater than 180 mg/dl) who had a long-standing polyuric syndrome is here presented. Hypernatremia and plasma osmolality elevated together with a low urinary osmolality led to the suspicion of diabetes insipidus, which was subsequently confirmed by the dehydration test and the administration of desmopressin sc. With 61% increase in the calculated urinary osmolarity one hour post desmopressin s.c., diabetes insipidus of central type was diagnosed. Nuclear Magnetic Resonance showed a bright spot with normal neurohypophysis, contributing to the diagnosis of the idiopathic form.

  4. Statins and Risk of New-Onset Diabetes Mellitus

    Science.gov (United States)

    ... if you have or are at risk for diabetes mellitus. What Does This US Food and Drug Administration Advisory Mean to Me? ... Cause Diabetes Mellitus? What If I Already Have Diabetes? Will Statin Therapy Make It Worse? What Does This US Food and Drug Administration Advisory Mean to Me? ...

  5. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-0190] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... individuals listed in this notice have recently requested such an exemption from the diabetes prohibition in...

  6. 78 FR 65754 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-11-01

    ...-2013-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 23 individuals and requested...

  7. 78 FR 76400 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0189] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 15 individuals and requested...

  8. 78 FR 77784 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-24

    ...-2013-0184] [4910-EX-P] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 26 individuals and requested...

  9. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ...-0186] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... individuals listed in this notice have recently requested such an exemption from the diabetes prohibition in...

  10. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ...-0184] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... such an exemption from the diabetes prohibition in 49 CFR 391.41(b)(3), which applies to drivers of...

  11. 76 FR 9867 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-2010-0427] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The....pdf . Background On January 10, 2011, FMCSA published a notice of receipt of Federal diabetes...

  12. 78 FR 78479 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-26

    ...-0192] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate... diabetes prohibition in 49 CFR 391.41(b)(3), which applies to drivers of CMVs in interstate commerce...

  13. Transient diabetes mellitus in a domestic ferret (Mustela putorius furo)

    Science.gov (United States)

    Duhamelle, Alexis; Langlois, Isabelle; Desmarchelier, Marion

    2015-01-01

    A 3.5-year-old spayed female ferret, fed a diet high in refined sugar, was referred for lethargy, polyuria, polydipsia, and polyphagia. Diabetic ketoacidosis was diagnosed. Treatment included insulin therapy and a low carbohydrate diet. Diabetes mellitus resolved 54 d later, and insulin therapy was discontinued. There has been no recurrence of the diabetes mellitus. PMID:26130836

  14. Transient diabetes mellitus in a domestic ferret (Mustela putorius furo)

    OpenAIRE

    Duhamelle, Alexis; Langlois, Isabelle; Desmarchelier, Marion

    2015-01-01

    A 3.5-year-old spayed female ferret, fed a diet high in refined sugar, was referred for lethargy, polyuria, polydipsia, and polyphagia. Diabetic ketoacidosis was diagnosed. Treatment included insulin therapy and a low carbohydrate diet. Diabetes mellitus resolved 54 d later, and insulin therapy was discontinued. There has been no recurrence of the diabetes mellitus.

  15. Screening for diabetes mellitus in learners residing in the Belhar ...

    African Journals Online (AJOL)

    Background Historically, children and adolescents have been diagnosed with type 1 diabetes mellitus and it was thought that type 2 diabetes mellitus occurred only in adults. There are increasing reports of type 2 diabetes in children globally, with some as young as eight years old being affected. The average age of ...

  16. Genetics of monegenic forms of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Tamara Leonidovna Kuraeva

    2011-03-01

    Full Text Available It is universally recognized that autoimmune type 1 diabetes mellitus (DM is not the only form of this disease in children. Increasingly more children andadolescents present with DM2, MODY, and rarer syndromal forms of DM. The actual prevalence of DM other than DM1 in children and adolescentsis unknown but may be estimated at 10%. Despite rare occurrence of genetic syndromes, they collectively account for almost 5% of DM cases amongchildren. The rapid upgrowth of molecular biology opens up a wide range of possibilities for designating various symptom complexes as nosologically selfconsistentforms. New genetic syndromes associated with DM are annually described. It is important both to adequately identify and treat manifestationsand complications of these syndromes in children and to provide relevant medico-genetic counseling and recommendations to the parents.Key words: non-immune diabetes mellitus, MODY, Wolfram syndrome, neonatal, syndromal forms

  17. Genetics of monegenic forms of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Tamara Leonidovna Kuraeva

    2011-03-01

    Full Text Available It is universally recognized that autoimmune type 1 diabetes mellitus (DM is not the only form of this disease in children. Increasingly more children and adolescents present with DM2, MODY, and rarer syndromal forms of DM. The actual prevalence of DM other than DM1 in children and adolescents is unknown but may be estimated at 10%. Despite rare occurrence of genetic syndromes, they collectively account for almost 5% of DM cases among children. The rapid upgrowth of molecular biology opens up a wide range of possibilities for designating various symptom complexes as nosologically selfconsistent forms. New genetic syndromes associated with DM are annually described. It is important both to adequately identify and treat manifestations and complications of these syndromes in children and to provide relevant medico-genetic counseling and recommendations to the parents. Key words: non-immune diabetes mellitus, MODY, Wolfram syndrome, neonatal, syndromal forms

  18. Teleconsultation in type 1 diabetes mellitus (TELEDIABE).

    Science.gov (United States)

    Bertuzzi, Federico; Stefani, Ilario; Rivolta, Benedetta; Pintaudi, Basilio; Meneghini, Elena; Luzi, Livio; Mazzone, Antonino

    2018-02-01

    The growing incidence of diabetes and the need to contain healthcare costs empower the necessity to identify new models of care. Telemedicine offers an acknowledged instrument to provide clinical health care at a distance, increasing patient compliance and the achievement of therapeutical goals. The objective was to test the feasibility and the efficacy in the improvement of the glycemic control of the teleconsultation for patients with type 1 diabetes mellitus. A randomized open-label, parallel arms, controlled trial was conducted in two diabetes centers in Italy. Participants affected by type 1 diabetes mellitus have been randomly (1:1) assigned to receive their visits as standard or a web-based care. Patients in the teleconsultation group can arrange their appointments on a Web site and can also have access to web educational courses or to nutritional and psychological counseling. The primary outcome was the assessment of glycemic control by HbA1c measurement after a 12-month follow-up. Overall 74 participants were followed for 1 year. HbA1c changes were not statistically different within (p = 0.56 for standard care group; p = 0.45 for telemedicine group) and between (p = 0.60) groups when considering differences from baseline to the end of the study. Patients randomized to teleconsultation reported reduced severe hypoglycemic episodes (p = 0.03). In addition, they were largely satisfied with the activities, perceived a good improvement in the self-management of the diabetes, and reported to have a time saving and a cost reduction. In conclusion, TELEDIABE proposes a new system for the management of patients with type 1 diabetes mellitus.

  19. Opções terapêuticas atuais para diabetes mellitus tipo 2 e doença arterial coronariana: prevenção secundária intensiva focada no treinamento físico versus revascularização percutânea ou cirúrgica Las opciones terapeuticas actuales en la diabetes mellitus 2 y la enfermedad coronaria: la prevención secundaria intensiva con el enfoque en el entrenamiento del ejercicio contra la revascularización quirurgica y percutanea Current therapeutical options in diabetes mellitus type 2 and coronary artery disease: intensive secondary prevention with focus on exercise training versus percutaneous or surgical revascularization

    Directory of Open Access Journals (Sweden)

    Sebastian Sixt

    2004-06-01

    Full Text Available O diabetes mellitus é um dos maiores fatores de risco para a doença arterial coronariana. A doença progride mais rápido em pacientes diabéticos e está associada com pior prognóstico. Embora a cirurgia de revascularização ou intervenção percutânea com a implantação de stent garanta rápido alívio dos sintomas em pacientes com doença arterial coronariana estabelecida, não existe substancial benefício prognóstico. Uma intervenção multifatorial incluindo medidas dietéticas, controle glicêmico, tratamento anti-hipertensivo e exercícios físicos regulares tem influência positiva nos fatores de risco modificáveis, na melhora de outras funções cardiovasculares e na tolerância ao exercício livre de angina.La diabetes mellitus es uno de los factores de riesgo mayores para la enfermedad de la arteria coronaria. La enfermedad progresa más rápidamente en los pacientes diabéticos y está asociada con uno de los más peores pronósticos. Aunque la cirugía de desviación o las intervenciones percutaneas con la implantación del stent proporcionan un alivio sintomático rápido para los pacientes con esta enfermedad de la arteria coronaria establecida, no tiene el beneficio de un pronóstico sustancial. Una intervención multi-factorial que incluye las medidas dietéticas, mando de sangre-glucosa, el tratamiento del antihipertensivo y ejercicio físico regular tiene una influencia positiva en los factores de riesgo modificables, y mejora entre otros la aptitud cardiovascular y la tolerancia del ejercicio libre de anginas.Diabetes mellitus is one of the major risk factors for coronary artery disease. The disease progresses faster in diabetic patients and is associated with a worse prognosis. Although bypass surgery or percutaneous interventions with stent implantation provide quick symptomatic relief for patients with stable coronary artery disease, it has no substantial prognostic benefit. A multifactorial intervention including

  20. Codificación geométrica y análisis de conglomerados para evaluar el control metabólico de pacientes con diabetes mellitus tipo 2 Geometric coding and cluster analysis to assess metabolic control of patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Ramón Alberto Rascón-Pacheco

    2010-04-01

    Full Text Available OBJETIVO: Determinar la frecuencia de las combinaciones de los parámetros de control metabólico por arriba de lo normal, usando la codificación geométrica y el análisis jerárquico de conglomerados, en pacientes con diabetes mellitus tipo 2 (DM2. MÉTODOS: Se desarrolló en México un estudio transversal descriptivo para evaluar a un grupo de 1 051 pacientes con DM2, cuyos criterios de inclusión eran tener uno o más de los siguientes valores: glucosa en ayunas > 130 mg/dL, colesterol total > 240 mg/dL, triglicéridos totales > 200 mg/dL, índice de masa corporal > 27 kg/m², y presión arterial sistólica mayor de 130 mmHg o presión arterial diastólica mayor de 85 mmHg. Por medio de codificaciones geométricas se obtuvieron las frecuencias de todas las combinaciones. Para definir similitudes entre las combinaciones se utilizó el método de análisis de conglomerados. RESULTADOS: Utilizando el instrumento propuesto, se observó que la combinación en pares con mayor número de sujetos estuvo representada por hiperglucemia-hipertrigliceridemia (7,3% e hiperglucemia-hipercolesterolemia (3,6%. Las policombinaciones de mayor frecuencia fueron hiperglucemia-hipercolesterolemia-hipertrigliceridemia (13,2% e hiperglucemia- hipertrigliceridemia-hipercolesterolemia-hipertensión (10,5%. CONCLUSIONES: La codificación geométrica y el análisis por conglomerados podrían llegar a ser un instrumento idóneo para evaluar el control metabólico de los pacientes con DM2, así como para identificar parámetros que contribuyan a mejorar su monitoreo y su tratamiento.OBJECTIVE: Determine the frequency of combinations of higher-than-normal metabolic control parameters, using geometric coding and hierarchical cluster analysis, in patients with type 2 diabetes (DM2 METHODOLOGY: A descriptive cross-sectional study was conducted in Mexico to assess a group of 1 051 patients with DM2. The inclusion criteria were to have one or more of the following values

  1. Sexual dysfunction in women with diabetes mellitus

    DEFF Research Database (Denmark)

    Giraldi, Annamaria; Kristensen, Ellids; Giraldi, Annamaria

    2010-01-01

    Diabetes mellitus (DM) is an increasing health concern throughout the world. DM is categorized as either type 1 (DM-1) or type 2 (DM-2), where DM-1 represents a lack of insulin production, and DM-2 is characterized by a relative lack of insulin (i.e., decreased sensitivity to the effect of insulin...... for such variation in findings across studies and uses these explanations as the basis for a discussion of differences between men's and women's sexuality....

  2. Diabetes Mellitus: A Public Health Challenge

    Directory of Open Access Journals (Sweden)

    Ydalsys Naranjo Hernández

    2016-01-01

    Full Text Available Diabetes mellitus is a syndrome characterized by hyperglycemia, due to an absolute or relative impairment of insulin secretion, insulin action, or both. It is a complex process of the carbohydrate, fat, and protein metabolism, which occurs as a result of such relative or complete impairment of insulin secretion from the β-cells of the pancreas or a defect in the insulin receptors.

  3. COIN EFFECT OF TUBERCULOSIS AND DIABETES MELLITUS

    OpenAIRE

    Deepthy. B. Nair

    2017-01-01

    Tuberculosis is a common disease caused by various strains of mycobacterium, usually Mycobacterium tuberculosis [1]. The first reference to tuberculosis in non European civilization was found in Vedas. Diabetes mellitus is group of metabolic diseases where the person has high blood sugar level either because the pancreas does not produce insulin or because cells do not respond to insulin that is produced. It may eventually leads to polyuria, polyphagia and polydipsia. This review is to reveal...

  4. Kedi ve Köpeklerde Diabetes Mellitus.

    OpenAIRE

    ŞİMŞEK, Aynur; İÇEN, Hasan

    2008-01-01

    Diabetes mellitus polidipsi, poliüri ve polifaji gibi klinik bulgularla karakterize endokrin bir hastalıktır. Bu derlemede, kedi ve köpeklerde yaygın olan hastalığın etiyoloji, patogenezis, kliniklaboratuar bulguları, tanı, ayırıcı tanı ve sağaltımına yönelik bilgilerin verilmesi amaçlanmıştır

  5. Radioimmunoassay of glicagon secretion in diabetes mellitus

    International Nuclear Information System (INIS)

    Milanova, St.; Koparanova, O.; Milkov, V.; Visheva, N.; Kurtev, I.; Maleeva, A.

    1988-01-01

    Radioimunoassay of glucagon, lh, fsh, aldosterone, cortisol, acth, sth and lth was performed using preparations from the firms SORIN, AMERSHAM and HOECHST. The basal glucagon secretion was estimated in 403 diabetic patients and 84 normal subjects. It was transitorily suppressed by glucose. The alpha-cellular reactivity in diabetic patients was stimulated by insulin-induced hypoglycemia and with arginine and vasopressin. The tested group of diabetic patients had absolute hyperglucagonemia, despite the hyperglycemia, which is an evidence of abnormal alpha-cellular function. The insulin-dependent nature of hyperglucagonemia in diabetes mellitus and the hyperreactivity of glucagon secretion after protein stimulation was demonstrated. The correlation of these results leads to essential diagnostic inferences

  6. Spices in the management of diabetes mellitus.

    Science.gov (United States)

    Bi, Xinyan; Lim, Joseph; Henry, Christiani Jeyakumar

    2017-02-15

    Diabetes mellitus (DM) remains a major health care problem worldwide both in developing and developed countries. Many factors, including age, obesity, sex, and diet, are involved in the etiology of DM. Nowadays, drug and dietetic therapies are the two major approaches used for prevention and control of DM. Compared to drug therapy, a resurgence of interest in using diet to manage and treat DM has emerged in recent years. Conventional dietary methods to treat DM include the use of culinary herbs and/or spices. Spices have long been known for their antioxidant, anti-inflammatory, and anti-diabetic properties. This review explores the anti-diabetic properties of commonly used spices, such as cinnamon, ginger, turmeric, and cumin, and the use of these spices for prevention and management of diabetes and associated complications. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Hypoglycemia, chronic kidney disease, and diabetes mellitus.

    Science.gov (United States)

    Alsahli, Mazen; Gerich, John E

    2014-11-01

    Hypoglycemia is a major problem associated with substantial morbidity and mortality in patients with diabetes and is often a major barrier to achieving optimal glycemic control. Chronic kidney disease not only is an independent risk factor for hypoglycemia but also augments the risk of hypoglycemia that is already present in people with diabetes. This article summarizes our current knowledge of the epidemiology, pathogenesis, and morbidity of hypoglycemia in patients with diabetes and chronic kidney disease and reviews therapeutic considerations in this situation. PubMed and MEDLINE were searched for literature published in English from January 1989 to May 2014 for diabetes mellitus, hypoglycemia, chronic kidney disease, and chronic renal insufficiency. Copyright © 2014 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  8. Fetal programming and gestational diabetes mellitus.

    Science.gov (United States)

    Monteiro, Lara J; Norman, Jane E; Rice, Gregory E; Illanes, Sebastián E

    2016-12-01

    Gestational diabetes mellitus is defined by new-onset glucose intolerance during pregnancy. About 2-5% of all pregnant women develop gestational diabetes during their pregnancies and the prevalence has increased considerably during the last decade. This metabolic condition is manifested when pancreatic β-cells lose their ability to compensate for increased insulin resistance during pregnancy, however, the pathogenesis of the disease remains largely unknown. Gestational diabetes is strongly associated with adverse pregnancy outcome as well as with long-term adverse effects on the offspring which likely occurs due to epigenetic modifications of the fetal genome. In the current review we address gestational diabetes and the short and long term complications for both mothers and offspring focusing on the importance of fetal programming in conferring risk of developing diseases in adulthood. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Acercamiento clínico y tratamiento nutricional a la diabetes mellitus 2

    OpenAIRE

    Córdova Soria, Luis Miguel; Solís Sánchez, Carlos Alberto

    2013-01-01

    El presente trabajo es una revisión bibliográfica de diversas investigaciones con relación a la Diabetes Mellitus 2, que es una Enfermedad Crónica No Transmisible de alta prevalencia a nivel mundial y en el Ecuador. Es una de las principales causas de mortalidad, no por la diabetes per se, sino más bien por las enfermedades relacionadas y que se producen como consecuencia o degeneración de la Diabetes Mellitus 2 debido a la edad o por un mal manejo de la enfermedad por parte de la persona afe...

  10. Epidemiology of diabetes mellitus in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Blackard, W G; Omori, Yoshiaki; Freedman, L R

    1964-03-12

    The clinical and epidemiological features of diabetes mellitus in Japan have been compiled and compared with data from other countries. Diabetes is basically the same in Japan as elsewhere: however, consideration of important differences has led to the following conclusions: The rarity of ketoacidosis in Japan is due to the mild carbohydrate defect present in most diabetics. The mild carbohydrate intolerance in diabetics is probably in part due to a high carbohydrate intake. Diabetic retinopathy is more common in women than in men in Japan; there are limited and conflicting data from the West on this point, but retinopathy, nephropathy and neuropathy occur about as frequently in Japan as in the West. Because of marked dietary differences between Japan and Western countries, these findings suggest that dietary fat has no significance in the pathogenesis of these lesions. Peripheral gangrene is distinctly unusual in Japanese diabetics. This suggests that either: the responsible vascular lesions are different from those responsible for nephropathy and retinopathy; or that small vessel lesions are the same but the lack of large vessel atherosclerosis in the population accounts for the decreased incidence of gangrene. Men have diabetes 2 or 3 times as commonly as women in Japan. If sex-limited inheritance is discarded as a possible reason, it is likely that adult-onset diabetes is more common in men than women except in those countries (the West) where women gain relatively large amounts of weight. The rarity of juvenile diabetes in Japan is best explained by the infrequency of responsible genetic factors. As a consequence, it is likely that juvenile diabetes is caused by different or additional genetic factors which are not significant in adult-onset diabetes. Diabetes prevalance varies sufficiently between different localities in the same country to render the concept of national prevalance of doubtful usefulness. 55 references, 3 figures, 3 tables.

  11. Type 2 diabetes mellitus in children and adolescents

    OpenAIRE

    Reinehr, Thomas

    2013-01-01

    Type 2 diabetes mellitus is emerging as a new clinical problem within pediatric practice. Recent reports indicate an increasing prevalence of type 2 diabetes mellitus in children and adolescents around the world in all ethnicities, even if the prevalence of obesity is not increasing any more. The majority of young people diagnosed with type 2 diabetes mellitus was found in specific ethnic subgroups such as African-American, Hispanic, Asian/Pacific Islanders and American Indians. Clinicians sh...

  12. Type 2 diabetes mellitus and exercise impairment.

    Science.gov (United States)

    Reusch, Jane E B; Bridenstine, Mark; Regensteiner, Judith G

    2013-03-01

    Limitations in physical fitness, a consistent finding in individuals with both type I and type 2 diabetes mellitus, correlate strongly with cardiovascular and all-cause mortality. These limitations may significantly contribute to the persistent excess cardiovascular mortality affecting this group. Exercise impairments in VO2 peak and VO2 kinetics manifest early on in diabetes, even with good glycemic control and in the absence of clinically apparent complications. Subclinical cardiac dysfunction is often present but does not fully explain the observed defect in exercise capacity in persons with diabetes. In part, the cardiac limitations are secondary to decreased perfusion with exercise challenge. This is a reversible defect. Similarly, in the skeletal muscle, impairments in nutritive blood flow correlate with slowed (or inefficient) exercise kinetics and decreased exercise capacity. Several correlations highlight the likelihood of endothelial-specific impairments as mediators of exercise dysfunction in diabetes, including insulin resistance, endothelial dysfunction, decreased myocardial perfusion, slowed tissue hemoglobin oxygen saturation, and impairment in mitochondrial function. Both exercise training and therapies targeted at improving insulin sensitivity and endothelial function improve physical fitness in subjects with type 2 diabetes. Optimization of exercise functions in people with diabetes has implications for diabetes prevention and reductions in mortality risk. Understanding the molecular details of endothelial dysfunction in diabetes may provide specific therapeutic targets for the remediation of this defect. Rat models to test this hypothesis are under study.

  13. Diabetes mellitus and periodontal health: dentists' knowledge.

    Science.gov (United States)

    Al-Khabbaz, Areej K; Al-Shammari, Khalaf F

    2011-01-01

    There is a strong body of evidence to support the relationship between periodontal diseases and diabetes mellitus. Unless dental practitioners are aware of this link, they cannot apply the information to their daily practice. The aim of the study was, therefore, to evaluate the knowledge of dental practitioners concerning the effect of diabetes on periodontal health. This was a cross-sectional survey of randomly selected dental practitioners in Kuwait. Participants were asked about specific periodontal complications which they believed that patients diagnosed with diabetes were more susceptible to. A total of 220 dental practitioners (133 general dental practitioners and 87 dental specialists) participated in the study. Less than 60% of all study participants reported that tooth loss due to periodontal reasons and periodontal abscess were frequent among diabetic patients. Dental specialists, especially periodontists, were significantly more aware of periodontal complications associated with diabetes. Factors significantly associated with having knowledge about the effect of diabetes on periodontal health in logistic regression analysis were dentists who were older and those who were specialists. The results of this study indicate that knowledge about the effects of diabetes on periodontal health among this sample of dental practitioners is generally low, and dentists may underestimate the outcomes of periodontal diseases in diabetic patients. Copyright © 2011 S. Karger AG, Basel.

  14. Diabetes mellitus in Bahrain: an overview.

    Science.gov (United States)

    Musaiger, A O

    1992-07-01

    Bahrain has faced a rapid transition in its socio-economic status, which resulted in great changes both in life-style and in patterns of health and disease. There has been a marked decline in infectious diseases and an increase in chronic diseases. Diabetes mellitus has become one of the most common public health problems in the country. In 1988 it was estimated that 3.4% of total deaths in Bahrain were due to diabetes. A community-based study among mothers aged 18 to 48 years showed that 8.5% of them had diabetes. The percentage was found to be higher among elderly Bahrainis (12.9%). Obesity, lack of physical activity, alteration in food habits, and change in social conditions have all played a vital role in the changing prevalence of diabetes in this country. The current programmes to manage and control diabetes are limited and ineffective. Thus measures to treat diabetes should be given a high priority in the national health policy. Training of physicians in the management of diabetes, public education, epidemiological surveys, and nutritional evaluation of local foods are among the most important measures needed to control diabetes in Bahrain.

  15. 78 FR 11210 - Notice of NIH Consensus Development Conference: Diagnosing Gestational Diabetes Mellitus

    Science.gov (United States)

    2013-02-15

    ... Development Conference: Diagnosing Gestational Diabetes Mellitus AGENCY: National Institutes of Health, HHS... ``Consensus Development Conference: Diagnosing Gestational Diabetes Mellitus.'' The conference will be open to... http://prevention.nih.gov/cdp/ . SUPPLEMENTARY INFORMATION: Gestational diabetes mellitus (GDM) is a...

  16. Masked hypertension in diabetes mellitus

    DEFF Research Database (Denmark)

    Franklin, Stanley S; Thijs, Lutgarde; Li, Yan

    2013-01-01

    Although distinguishing features of masked hypertension in diabetics are well known, the significance of antihypertensive treatment on clinical practice decisions has not been fully explored. We analyzed 9691 subjects from the population-based 11-country International Database on Ambulatory Blood...

  17. [Abdominal ultrasonography in patients with diabetes mellitus. Part 1: Liver].

    Science.gov (United States)

    Jenssen, C; Pietsch, C; Gottschalk, U; Barreiros, A P; Teufel, A; Cui, X W; Dietrich, C F

    2015-04-01

    In patients with diabetes mellitus, abdominal ultrasonography is the appropriate diagnostic technique to detect and to follow-up secondary and accompanying diseases of the liver, the kidneys, the pancreas, the gastrointestinal tract and of abdominal vessels. Moreover, pancreatic and hepatic diseases may be realized which are of etiological importance for diabetes mellitus. Based on a systematic survey of the published literature, this review in 3 parts will describe the value of abdominal ultrasonography in patients with diabetes mellitus. Part 1 deals with the diagnostic relevance and particular findings of ultrasonographic methods in hepatic manifestations and complications of diabetes mellitus. © Georg Thieme Verlag KG Stuttgart · New York.

  18. The Classification of Diabetes Mellitus Using Kernel k-means

    Science.gov (United States)

    Alamsyah, M.; Nafisah, Z.; Prayitno, E.; Afida, A. M.; Imah, E. M.

    2018-01-01

    Diabetes Mellitus is a metabolic disorder which is characterized by chronicle hypertensive glucose. Automatics detection of diabetes mellitus is still challenging. This study detected diabetes mellitus by using kernel k-Means algorithm. Kernel k-means is an algorithm which was developed from k-means algorithm. Kernel k-means used kernel learning that is able to handle non linear separable data; where it differs with a common k-means. The performance of kernel k-means in detecting diabetes mellitus is also compared with SOM algorithms. The experiment result shows that kernel k-means has good performance and a way much better than SOM.

  19. ANÁLISE DAS DIFICULDADES RELACIONADAS ÀS ATIVIDADES DIÁRIAS DE CRIANÇAS E ADOLESCENTE COM DIABETES MELLITUS TIPO 1: DEPOIMENTO DE MÃES ANÁLISIS DE LAS DIFICULTADES RELACIONADAS CON LAS ACTIVIDADES DIARIAS DE LOS NIÑOS Y ADOLESCENTES CON DIABETES MELLITUS TIPO 1: DECLARACIONES DE LAS MADRES ANALYSIS OF DIFFICULTIES REGARDING THE DAILY ACTIVITIES OF TEENAGERS AND CHILDREN WITH TYPE-1 DIABETES MELLITUS: MOTHERS' ACCOUNTS

    Directory of Open Access Journals (Sweden)

    Maria Lúcia Zanetti

    2001-11-01

    Full Text Available Estudo descritivo com o objetivo de analisar as dificuldades que as mães de crianças e adolescentes diabéticos tipo 1 apresentam face as atividades diárias com o filho, partindo da premissa de que fatores de ordem econômica, social, pessoal e emocional da família interferem para obtenção de um bom controle metabólico. Através de roteiro semi-estruturado de entrevista aplicado a trinta mães, obteve-se os dados cuja análise obedeceu às normas preconizadas para estudos descritivos. Os resultados permitiram concluir que as mães apontaram como dificuldades nas atividades diárias com os filhos: reuniões de convivência social; motivá-lo a realizar atividade física; dieta; adaptação escolar; relacionamento com a equipe de saúde e comportamento do filho frente aos demais irmãos. Foi evidenciada a necessidade de trabalho planejado e integrado por equipe multiprofissional junto às famílias, direcionado para cada dificuldade abordada, observando-se sua interdependência para o êxito do cuidado à criança e adolescente diabético tipo 1.Estudio descriptivo con el objetivo de analizar las dificultades que las madres de los niños y adolescentes diabéticos tipo 1, presentan de cara a las actividades diarias con el hijo; partiendo de la premisa de que factores de orden económico, social, personal y emocional de la familia interfieren para la obtención de un buen control metabólico. A través de un guión de entrevista semi-estructurada aplicado a treinta madres, se obtuvieron los datos, cuyo análisis se realizó según las normas preconizadas para estudios descriptivos. Los resultados permitieron concluir que las madres anotan como dificultades en las actividades diarias con los hijos: reuniones de convivencia social, motivarlo a realizar la actividad física, dieta, adaptación escolar, relación con el equipo de salud y el comportamiento del hijo frente a los demás hermanos. Se hizo evidente la necesidad de un trabajo planeado

  20. Diabetes knowledge among Greek Type 2 Diabetes Mellitus patients.

    Science.gov (United States)

    Poulimeneas, Dimitrios; Grammatikopoulou, Maria G; Bougioukli, Vasiliki; Iosifidou, Parthena; Vasiloglou, Maria F; Gerama, Maria-Assimina; Mitsos, Dimitrios; Chrysanthakopoulou, Ioanna; Tsigga, Maria; Kazakos, Kyriakos

    2016-01-01

    Diabetes knowledge has been shown to improve glycemic control and associate with several demographic parameters. In Greece, a country with high obesity rates, disease knowledge has never been evaluated in diabetic patients. This cross sectional study aimed to assess diabetes knowledge and its associations between social and demographic parameters, among Greek type 2 diabetes mellitus (T2DM) patients. One hundred fifty nine patients with T2DM were recruited from an urban and a rural clinic in Greece. Diabetes knowledge was assessed with the Brief Diabetes Knowledge Test (DKT). Basic anthropometry was performed. Data regarding glycemic control and sociodemographic characteristics were collected from the patients' medical files. Greek T2DM patients demonstrated poor disease knowledge (mean DKT score 8.3±2.2/14.0 and mean DKT as a percent of correct answers 59.6±15.8%). No differences were observed between sex, place of residence, or glycemic control, among subjects. Patients with higher education demonstrated greater diabetes knowledge. Simple obesity with concurrent central obesity or suboptimal glycemic control decreased diabetes knowledge among participants. Additionally, waist circumference was inversely correlated to diabetes knowledge. Based on the DKT, Greek patients exhibit poor diabetes knowledge. This study provides evidence for the need for better diabetes education in order to ameliorate disease outcome. Copyright © 2016 SEEN. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. Diabetes Mellitus como causa de perda auditiva Diabetes mellitus as etiological factor of hearing loss

    Directory of Open Access Journals (Sweden)

    Clícia Adriana S. Maia

    2005-04-01

    Full Text Available Os pacientes com diabetes mellitus freqüentemente apresentam sintomas como tontura, zumbidos e hipoacusia. Via de regra, a perda auditiva é do tipo sensorioneural, confundindo-se, por vezes, com presbiacusia, principalmente por ocorrer em pacientes acima dos 40 anos de idade. A angiopatia e a neuropatia causadas pelo diabetes mellitus têm sido considerados importantes fatores responsáveis pelas manifestações vestibulococleares nesses pacientes. Porém, existe controvérsia no que se refere à etiopatogênese da perda auditiva, sendo que parte dos autores advoga que ela ocorre devido à neuropatia, outra parte à angiopatia, e outra, ainda, à associação das duas. Porém há também os que entendem que o diabetes mellitus e a perda auditiva poderiam ser partes integrantes de uma síndrome genética e não dependentes entre si. Realizamos uma extensa revisão bibliográfica procurando analisar se há relação "causa e efeito" entre o diabetes mellitus e a perda auditiva. Pudemos observar que, apesar do grande número de estudos realizados, a controvérsia ainda é grande, sendo que novas perspectivas, como no campo da genética, estão sendo estudadas, mostrando que novos rumos podem ser tomados para se chegar à conclusão do tema.Patients with diabetes mellitus often show symptoms such as dizziness, tinnitus, and hearing impairment. In general, hearing loss is sensorineural, which is sometimes confused with presbycusis, mainly because it develops in patients older than 40 years of age. Angiopathy and neuropathy caused by diabetes mellitus have been considered important factors for the vestibular-cochlear disorders found in these patients. However, there is controversy regarding the etiopathogenesis of hearing loss, as some researchers support that it develops due to neuropathy, others say it is due to angiopathy, or even a combination of both. Yet, some researchers believe diabetes mellitus and hearing loss are part of a genetic

  2. Complicações microvasculares e disfunção autonômica cardíaca em pacientes com diabete melito tipo 1 Complicaciones microvasculares y disfunción autonómica cardíaca en pacientes con diabetes mellittus tipo 1 Microvascular complications and cardiac autonomic dysfunction in patients with diabetes mellitus type 1

    Directory of Open Access Journals (Sweden)

    Fernando K Almeida

    2011-06-01

    hallazgos sugestivos de NAC durante la realización de la prueba ergométrica (PE y nefropatía y retinopatía en pacientes con DM tipo 1. METHODS: Realizamos un estudio transversal con 84 pacientes con DM tipo 1. Todos los pacientes fueron sometidos a evaluación clínica y laboratorial y llevaron a cabo PE, siendo que aquellos que presentaron hallazgos sugestivos de isquemia miocárdica fueron excluidos del análisis de los datos (n = 3. La evaluación de complicaciones microvasculares (retinopatía y nefropatía se realizó en la muestra. RESULTS: Los pacientes con nefropatía y aquellos con retinopatía alcanzaron una frecuencia cardíaca (FC durante el nivel máximo de ejercicio (FC máxima menor y presentaron aumento menor de FC con relación al reposo (ΔFC pico cuando comparados con aquellos sin estas complicaciones. Estos pacientes también presentaron una menor reducción de la FC en el segundo y 4º minutos tras el final de la prueba (ΔFC recuperación 2 y 4 minutos. Tras la realización de análisis multivariado con control para los posibles factores de confusión, los ΔFC recuperación en dos y 4 minutos, FC máxima y el ΔFC pico permanecieron significativamente asociados a la retinopatía; y los ΔFC recuperación en el segundo y 4º minutos permanecieron asociados a la presencia de nefropatía. CONCLUSION: Se puede considerar la PE como un instrumento adicional para la detección precoz de NAC y para identificar pacientes en un mayor riesgo para complicaciones microvasculares de la diabetes.BACKGROUND: The presence of cardiac autonomic neuropathy (CAN in patients with diabetes mellitus (DM is associated with increased mortality and chronic microvascular complications of diabetes. OBJECTIVE: To investigate a possible association between specific findings of CAN during exercise testing (ET and nephropathy and retinopathy in patients with type 1 DM. METHODS: We conducted a cross-sectional study of 84 patients with type 1 DM. All patients underwent clinical

  3. Predictive factors for the development of diabetes in women with previous gestational diabetes mellitus

    DEFF Research Database (Denmark)

    Damm, P.; Kühl, C.; Bertelsen, Aksel

    1992-01-01

    OBJECTIVES: The purpose of this study was to determine the incidence of diabetes in women with previous dietary-treated gestational diabetes mellitus and to identify predictive factors for development of diabetes. STUDY DESIGN: Two to 11 years post partum, glucose tolerance was investigated in 241...... women with previous dietary-treated gestational diabetes mellitus and 57 women without previous gestational diabetes mellitus (control group). RESULTS: Diabetes developed in 42 (17.4%) women with previous gestational diabetes mellitus (3.7% insulin-dependent diabetes mellitus and 13.7% non...... of previous patients with gestational diabetes mellitus in whom plasma insulin was measured during an oral glucose tolerance test in late pregnancy a low insulin response at diagnosis was found to be an independent predictive factor for diabetes development. CONCLUSIONS: Women with previous dietary...

  4. Mechanism linking diabetes mellitus and obesity

    Directory of Open Access Journals (Sweden)

    Al-Goblan AS

    2014-12-01

    Full Text Available Abdullah S Al-Goblan,1 Mohammed A Al-Alfi,1 Muhammad Z Khan2 1Diabetes Center, King Fahad Specialist Hospital, Buraidah, Qassim, Kingdom of Saudi Arabia; 2Sulaiman AlRajhi Colleges, Al Bukairiyah, Kingdom of Saudi Arabia Abstract: Body mass index has a strong relationship to diabetes and insulin resistance. In obese individuals, the amount of nonesterified fatty acids, glycerol, hormones, cytokines, proinflammatory markers, and other substances that are involved in the development of insulin resistance, is increased. The pathogenesis in the development of diabetes is based on the fact that the β-islet cells of the pancreas are impaired, causing a lack of control of blood glucose. The development of diabetes becomes more inevitable if the failure of β-islet cells of the pancreas is accompanied by insulin resistance. Weight gain and body mass are central to the formation and rising incidence of type 1 and type 2 diabetes. This literature review will demonstrate the facts that link obesity with insulin resistance and pancreatic β-cell dysfunction. In conclusion, new approaches in managing and preventing diabetes in obese individuals must be studied and investigated based on the facts. Keywords: diabetes mellitus, obesity, insulin resistance

  5. Autonomic neuropathy in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Alberto eVerrotti

    2014-12-01

    Full Text Available Diabetic autonomic neuropathy (DAN is a serious and common complication of diabetes, often overlooked and misdiagnosed. It is a systemic-wide disorder that may be asymptomatic in the early stages. The most studied and clinically important form of DAN is cardiovascular autonomic neuropathy (CAN defined as the impairment of autonomic control of the cardiovascular system in patients with diabetes after exclusion of other causes. The reported prevalence of DAN varies widely depending on inconsistent definition, different diagnostic method, different patient cohorts studied. The pathogenesis is still unclear and probably multifactorial. Once DAN becomes clinically evident, no form of therapy has been identified which can effectively stop or reverse it. Prevention strategies are based on strict glycemic control with intensive insulin treatment, multifactorial intervention and lifestyle modification including control of hypertension, dyslipidemia, stop smoking, weight loss and adequate physical exercise. The present review summarizes the latest knowledge regarding clinical presentation, epidemiology, pathogenesis and management of DAN, with some mention to childhood and adolescent population.

  6. Diagnosis and treatment of diabetes mellitus in chronic pancreatitis.

    Science.gov (United States)

    Ewald, Nils; Hardt, Philip D

    2013-11-14

    Diabetes secondary to pancreatic diseases is commonly referred to as pancreatogenic diabetes or type 3c diabetes mellitus. It is a clinically relevant condition with a prevalence of 5%-10% among all diabetic subjects in Western populations. In nearly 80% of all type 3c diabetes mellitus cases, chronic pancreatitis seems to be the underlying disease. The prevalence and clinical importance of diabetes secondary to chronic pancreatitis has certainly been underestimated and underappreciated so far. In contrast to the management of type 1 or type 2 diabetes mellitus, the endocrinopathy in type 3c is very complex. The course of the disease is complicated by additional present comorbidities such as maldigestion and concomitant qualitative malnutrition. General awareness that patients with known and/or clinically overt chronic pancreatitis will develop type 3c diabetes mellitus (up to 90% of all cases) is rather good. However, in a patient first presenting with diabetes mellitus, chronic pancreatitis as a potential causative condition is seldom considered. Thus many patients are misdiagnosed. The failure to correctly diagnose type 3 diabetes mellitus leads to a failure to implement an appropriate medical therapy. In patients with type 3c diabetes mellitus treating exocrine pancreatic insufficiency, preventing or treating a lack of fat-soluble vitamins (especially vitamin D) and restoring impaired fat hydrolysis and incretin secretion are key-features of medical therapy.

  7. Association of ABO blood groups with diabetes mellitus

    African Journals Online (AJOL)

    2010-02-08

    Feb 8, 2010 ... We studied the association of ABO blood groups with DM type 2. Patients and methodology: It was ... dent diabetes mellitus (NIDDM or type 2), characterized by elevated insulin levels ... diabetic ketoacidosis. Sample size was ...

  8. Anaemia in Patients with Diabetes Mellitus attending regular ...

    African Journals Online (AJOL)

    Anaemia in Patients with Diabetes Mellitus attending regular Diabetic ... Nigerian Journal of Health and Biomedical Sciences ... some patients may omit important food items in their daily diet for fear of increasing their blood sugar level.

  9. Cognitive impairment in patients with type 2 diabetes mellitus ...

    African Journals Online (AJOL)

    Cognitive impairment in patients with type 2 diabetes mellitus: Perspectives and ... may have a deteriorating effect on mental health including a decline in cognitive ... of Diabetes; Functional Foods and Human Diet; Quality of Life and Wellness ...

  10. 76 FR 26792 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-05-09

    ... manage his/her diabetes mellitus, received education related to diabetes management, and is on a stable..., Crispin Tabangcura, Jr., Blake A. Tice, Eric F. Ware, Harold E. Watters, Terry Wilson and John B. Wojcicki...

  11. Gestational Diabetes Mellitus and Future Cardiovascular Risk: An Update

    Directory of Open Access Journals (Sweden)

    S. Burlina

    2016-01-01

    Full Text Available The prevalence of gestational diabetes mellitus is increasing in parallel with the rising prevalence of type 2 diabetes and obesity around the world. Current evidence strongly suggests that women who have had gestational diabetes mellitus are at greater risk of cardiovascular disease later in life. Given the growing prevalence of gestational diabetes mellitus, it is important to identify appropriate reliable markers of cardiovascular disease and specific treatment strategies capable of containing obesity, diabetes, and metabolic syndrome in order to reduce the burden of cardiovascular disease in the women affected.

  12. Clinical and biochemical profile of lean type 2 diabetes mellitus

    OpenAIRE

    Barma, Punyakrit Deb; Ranabir, Salam; Prasad, Lallan; Singh, Thangjam Premchand

    2011-01-01

    Background: Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass index < 19 kg/m 2 . Materials and Methods: We evaluated 100 cases of lean type 2 diabetes mellitus (62 males and 38 females). Results and Conclusion: The mean duration of diabetes was 51.7 months (rang...

  13. Homocysteine, Cortisol, Diabetes Mellitus, and Psychopathology

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    K. Kontoangelos

    2015-01-01

    Full Text Available Objective. This study investigates the association of homocysteine and cortisol with psychological factors in type 2 diabetic patients. Method. Homocysteine, cortisol, and psychological variables were analyzed from 131 diabetic patients. Psychological factors were assessed with the Eysenck Personality Questionnaire (EPQ, Hostility and Direction of Hostility Questionnaire (HDHQ, the Symptom Checklist 90-R (SCL 90-R, the Zung Self-Rating Depression Scale (ZDRS, and the Maudsley O-C Inventory Questionnaire (MOCI. Blood samples were taken by measuring homocysteine and cortisol in both subgroups during the initial phase of the study (T0. One year later (T1, the uncontrolled diabetic patients were reevaluated with the use of the same psychometric instruments and with an identical blood analysis. Results. The relation of psychoticism and homocysteine is positive among controlled diabetic patients (P value = 0.006<0.05 and negative among uncontrolled ones (P value = 0.137. Higher values of cortisol correspond to lower scores on extraversion subscale (rp=-0.223, P value = 0.010. Controlled diabetic patients showed a statistically significant negative relationship between homocysteine and the act-out hostility subscale (rsp=-0.247, P=0.023. There is a statistically significant relationship between homocysteine and somatization (rsp=-0.220, P=0.043. Conclusions. These findings support the notion that homocysteine and cortisol are related to trait and state psychological factors in patients with diabetes mellitus type 2.

  14. Factores de riesgo de diabetes mellitus tipo 2 en mujeres postmenopaúsicas

    OpenAIRE

    Acosta Naranjo, William Daniel; Esnal, Virginia

    2012-01-01

    La Diabetes Mellitus tipo 2 (DM 2) es una enfermedad con impacto socio sanitario por su elevada frecuencia y mortalidad cardiovascular. En Uruguay, como en la población mundial, la DM2 es más frecuente en mujeres. Este trabajo describe factores de riesgo en mujeres postmenopaúsicas que nosotros, los investigadores de este manuscrito, atendemos.

  15. RELACIÓN DE LOS NIVELES SÉRICOS DE LÍPIDOS Y LIPOPROTEÍNAS CON EL POLIMORFISMO ε 2, ε 3 Y ε 4 DEL GEN DE LA APOLIPOPROTEÍNA E, EN INDIVIDUOS CON DIABETES MELLITUS TIPO 2 Y EL RIESGO CARDIOVASCULAR

    Directory of Open Access Journals (Sweden)

    N. Coiza-Vargas

    2005-12-01

    Full Text Available Este trabajo describe la respuesta del perfil lipídico según el genotipo de la apolipoproteína E en personas con diabetes mellitus tipo 2 y la presencia o no de riesgo cardiovascular, por medio de la revisión sistemática de artículos científicos publicados entre 1990 y 2003. Seis estudios cumplieron con los criterios de inclusión y fueron seleccionados para realizar el trabajo de investigación.Inicialmente se realizó una descripción de características generales de los estudios y se utilizó la prueba estadística Chi - cuadrado para determinar diferencias entre grupos. Se encontró que el 66.6% de los artículos fueron realizados en Europa, el promedio de personas de los estudios fue de 473 y el promedio de edad estuvo en los 58 años.La distribución del genotipo E 3/3 (78.2%, fue la de mayor prevalencia en los diferentes grupos de diabéticos, seguido de E 4/3 en 12.8% y E 3/2 con un 8.7%. Las fracciones lipídicas más elevadas en los estudios fueron las de colesterol total, colesterol LDL y triglicéridos. Se observó que el polimorfismo de la apo E influye sobre el perfil lipídico, y por tanto, en el desarrollo de la enfermedad cardiovascular en los sujetos con DM tipo 2.

  16. CARDIAC REHABILITATION IN PATIENTS WITH DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    Marzieh Saeidi

    2010-12-01

    Full Text Available AbstractINTRODUCTION: Prevalence of cardiovascular diseases (CVD is 19.4% in Iran anddiabetes mellitus is an important CVD risk factor in this country. Non-insulin-dependentdiabetes mellitus (type II DM is associated with increased morbidity and mortality due toatherosclerosis. With cardiac rehabilitation (CR we can modify CVD risk factors such astype II DM and play an important role in decreasing its mortality and morbidity. Weinvestigated the effects of CR on cardiac patients with and without type II DM.METHODS: In this retrospective before-and-after study we analyzed data from 496 cardiacpatients (419 with type II DM and 77 without type II DM. All of the subjects completeddemographic data questionnaires and underwent weight and height measurement, exercisetest to assess exercise capacity (EC, echocardiography, and blood test to assess lipidprofile and fasting blood glucose. The subjects then participated in a 24-session CRprogram. Each session consisted of 10 minutes warm-up, 40 minutes aerobic exercise, 10minutes cool-down and 20 minutes relaxation. They also took part in 8 educational sessionson life style modification, diet therapy and stress management supervised by CR team (acardiologist, a physician, a physiotherapist, a nurse, a nutritionist and a psychiatrist. At theend of the program, all measurements, exams and tests were repeated. Data were analyzedwith SPSS11.5 using independent t-test at level of P<0.05.RESULTS: We studied 419 non-diabetics (mean age: 55.61±9.41 years and 77 diabetics(mean age: 58.59±7.76 years. Mean EC increased significantly after CR in both groups. Inthe diabetic group, EC increased significantly compared to the non-diabetic group(62.21±133.40 vs. 33.68±31/42, P=0.02. Mean levels of triglyceride, cholesterol, LDLcholesterol,as well as body mass index and heart rate decreased significantly after CR inboth groups. However, no significant difference was seen between the two groups in respectof these variables

  17. EVALUATION OF DRY EYES IN DIABETES MELLITUS

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    Anshu Sharma

    2017-12-01

    Full Text Available BACKGROUND According to the National Eye Institute, dry eye is a condition in which the eye does not produce tears properly. It can also involve tears not having the right consistency or evaporating too quickly. Tears are necessary to help maintain moisture on the surface of the eye and for clear vision. Diabetes is often associated with several significant ocular conditions such as retinopathy, refractive changes, cataracts, glaucoma and macular oedema. However, one of the most common ocular complications associated with diabetes is dry eye. The aim of the study is to study the prevalence of dry eyes in diabetes mellitus and to evaluate ocular and other risk factors relevant to diabetic dry eyes. MATERIALS AND METHODS A hospital-based cross-sectional clinical study of 100 diabetic patients who presented to the Department of Ophthalmology, Santosh Medical College and Hospital, Ghaziabad, between January 2016 to June 2017 was conducted. Detailed diabetic history was recorded. Assessment of anterior segment via slit-lamp biomicroscopy was done. The examinations for dry eyes included Schirmer's test, tear breakup time, fluorescein and rose Bengal staining. RESULTS Sixty two (62% diabetic patients had dry eye. The prevalence in type I was 3% and prevalence in type II was 59%. Dry eye prevalence was maximum in those above 40 years of age. Symptoms like reduced corneal sensation (44% and meibomitis (20% were major attributable risk factors. Ocular surface damage was predominantly superficial punctate keratitis. Retinopathy was not statistically associated with the prevalence of dry eyes. CONCLUSION Diabetes and dry eye appears to be a common association. Reduction in the modifiable risk factors of dry eye is essential to reduce its prevalence. No significant statistical correlation was found between retinopathy and dry eyes. However, examination for dry eyes should be an integral part of the assessment of diabetic eye disease.

  18. Post-transplantation diabetes mellitus: an overview

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    Igor Aleksandrovich Sklyanik

    2015-04-01

    Full Text Available This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM – a specific complication after solid organ transplantation.A search of the databases eLibrary, PubMed and Scopus using the keywords «posttransplantation diabetes mellitus», «new onset diabetes after transplantation», «transplantation» and «immunosuppression» yielded in 523 results, including four from Russian literature (one original research manuscript. The analysis included original research, reviews, meta-analyses and monographs published not before 2005 in Russian and English. A total of 60 relevant original researches and reviews were included in this review.Diagnostic criteria, disease risk factors and potential pathogenic mechanisms were all considered. The mechanisms of the diabetogenic effect of modern immunosuppressive drugs were analysed. The principles of pre- and post-transplantation screening for PTDM and optimal management strategies for patients with PTDM are presented. The current controversial issues concerning the various aspects of PTDM are discussed.

  19. Arrhythmias in type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Gaurav Agarwal

    2017-01-01

    Full Text Available Chronic hyperglycaemia of Type 2 diabetes mellitus causes long term damage to heart resulting in coronary artery disease (CAD, myocardial infarction (MI, congestive heart failure (CHF, and sudden death from arrhythmias. AIMS: To study the prevalence of different types of arrhythmias in T2DM, particularly in association with Cardiac Autonomic Neuropathy (CAN. METHODS: A cross-sectional study including 100 patients of Type 2 Diabetes Mellitus (T2DM presenting with cardiac arrhythmias, was done at our hospital over 2 years. Detailed history along with physical examination and tests for CAN were done. Routine investigations along with echocardiography, stress test, Holter monitoring were done. RESULTS: Sinus Tachycardia (ST was the commonest arrhythmia, found in 32% of patients. 20% had Complete Heart Block (CHB, 15% had Sinus Bradycardia (SB, and 15% had Atrial Fibrillation (AF. Ventricular Premature Complex (VPC was found in 10% and 3% had Atrial Premature Complex (APC. 3% had first degree AV block, whereas 1% had Paroxysmal Supra Ventricular Tachycardia (PSVT, and another 1% had Ventricular Tachycardia (VT. Poorly controlled diabetes and co-morbidities was associated with higher incidence of arrhythmias. 62% of patients had prolonged QTc, majority of which had CAN. Most of the patients responded to standard therapy.

  20. Gestational diabetes mellitus in Tanzania : public health perspectives

    NARCIS (Netherlands)

    Mwanri, A.W.

    2015-01-01

    Gestational diabetes mellitus in Tanzania – public health perspectives

    Abstract

    Background: Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance resulting in hyperglycaemia of variable severity with onset or

  1. Peptide and protein biomarkers for type 1 diabetes mellitus

    Science.gov (United States)

    Zhang, Qibin; Metz, Thomas O.

    2016-08-30

    A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.

  2. Type 2 diabetes mellitus in children and adolescents

    Science.gov (United States)

    Reinehr, Thomas

    2013-01-01

    Type 2 diabetes mellitus is emerging as a new clinical problem within pediatric practice. Recent reports indicate an increasing prevalence of type 2 diabetes mellitus in children and adolescents around the world in all ethnicities, even if the prevalence of obesity is not increasing any more. The majority of young people diagnosed with type 2 diabetes mellitus was found in specific ethnic subgroups such as African-American, Hispanic, Asian/Pacific Islanders and American Indians. Clinicians should be aware of the frequent mild or asymptomatic manifestation of type 2 diabetes mellitus in childhood. Therefore, a screening seems meaningful especially in high risk groups such as children and adolescents with obesity, relatives with type 2 diabetes mellitus, and clinical features of insulin resistance (hypertension, dyslipidemia, polycystic ovarian syndrome, or acanthosis nigricans). Treatment of choice is lifestyle intervention followed by pharmacological treatment (e.g., metformin). New drugs such as dipeptidyl peptidase inhibitors or glucagon like peptide 1 mimetics are in the pipeline for treatment of youth with type 2 diabetes mellitus. However, recent reports indicate a high dropout of the medical care system of adolescents with type 2 diabetes mellitus suggesting that management of children and adolescents with type 2 diabetes mellitus requires some remodeling of current healthcare practices. PMID:24379917

  3. De grondslagen van de behandeling van diabetes mellitus

    NARCIS (Netherlands)

    Nieveen, Jakob

    1948-01-01

    The object of this study was to trace which results were reached with the treatment of 394 diabetes mellitus patients and which factors were important for the results. As material for our research were used the data of the diabetes mellitus patients treated between 1930 and 1944 in the clinic for

  4. Glycaemic Control amongst Persons with Diabetes Mellitus in Benin ...

    African Journals Online (AJOL)

    Conclusion: This study has shown that poor glycaemic control is common amongst persons with diabetes mellitus in Benin City. Studies have shown that good glycaemic control prevents and delays the complications of diabetes mellitus. We therefore recommend that health education on the benefits of good glycaemic ...

  5. Diagnosing gestational diabetes mellitus in the Danish National Birth Cohort

    DEFF Research Database (Denmark)

    Olsen, Sjurdur F; Houshmand-Oeregaard, Azedeh; Granström, Charlotta

    2017-01-01

    evaluated gestational diabetes mellitus status based on results from oral glucose tolerance tests, fasting blood glucose and Hb1c values, as well as diagnoses made by local obstetricians. RESULTS: The audit categorized 783 pregnancies as gestational diabetes mellitus, corresponding to 0.89% of the 87 792...

  6. Diabetes mellitus complicating β-thalassemia: a case report

    African Journals Online (AJOL)

    A case of beta-thalassemia major complicated by diabetes mellitus in a Fiji national is presented. The mechanisms involved in the pathogenesis of this complication are highlighted. Keywords: β-thalassemia, diabetes mellitus, iron overload. Annals of African Medicine Vol.2(1) 2003: 36-38 ...

  7. Risk factors for gestational diabetes mellitus in Sudanese pregnant ...

    African Journals Online (AJOL)

    McRoy

    Key words: Diabetes mellitus, gestation, risk factors, Sudan. INTRODUCTION. Gestational diabetes mellitus (GDM) is a universal risk factor for maternal and neonatal morbidity and mortality.[1] Low gestational age, neonatal macrosomia, hypoglycemia, respiratory distress syndrome are frequent complications of GDM and ...

  8. Irregular menses: an independent risk factor for gestational diabetes mellitus.

    Science.gov (United States)

    Haver, Mary Claire; Locksmith, Gregory J; Emmet, Emily

    2003-05-01

    Our purpose was to determine whether a history of irregular menses predicts gestational diabetes mellitus independently of traditional risk factors. We analyzed demographic characteristics, body mass index, and menstrual history of 85 pregnant women with gestational diabetes mellitus and compared them with 85 systematically selected control subjects who were matched for age, race, and delivery year. Subjects with pregestational diabetes mellitus, previous gestational diabetes mellitus, family history of diabetes mellitus, weight >200 pounds, previous macrosomic infants, or previous stillbirth were excluded. Demographic characteristics between case and control groups were similar. Mean body mass index was higher among cases (26.5 kg/m(2)) versus control subjects (24.5 kg/m(2), P =.004). Irregular cycles were more prevalent in the cases (24% vs 7%, P =.006). With the use of body mass index as a stratification factor, menstrual irregularity maintained a strong association with gestational diabetes mellitus (P =.014). A history of irregular menstrual cycles was a significant independent predictor of gestational diabetes mellitus. If selective screening is implemented for gestational diabetes mellitus, such history should be considered in the decision of whom to test.

  9. Problems faced by newly diagnosed diabetes mellitus patients at ...

    African Journals Online (AJOL)

    Diabetes mellitus can be a frightening experience for newly diagnosed patients. The aim of this study was to determine and describe the problems faced by newly diagnosed diabetes mellitus patients at primary healthcare facilities at Mopani district, Limpopo Province. A qualitative, descriptive and contextual research ...

  10. Prevalence and awareness of type 2 diabetes mellitus among adult ...

    African Journals Online (AJOL)

    Type 2 diabetes mellitus (T2DM) prevalence is increasing rapidly around the world. This cross-sectional study was conducted to assess the prevalence and awareness of type 2 diabetes mellitus in Mwanza city, Tanzania. A multistage random sampling technique was used to obtain representative subjects. Information ...

  11. Prevalence of diabetes mellitus among adults in rural north central ...

    African Journals Online (AJOL)

    Background: Diabetes Mellitus is one of the noncommunicable diseases and a public health problem facing the world. This chronic disease is expected to rise due to rapid population growth, urbanization, aging, obesity and physical inactivity. The objective of this study was to determine the prevalence of Diabetes Mellitus ...

  12. Tuberculous pyomyositis in a patient with diabetes Mellitus | Edo ...

    African Journals Online (AJOL)

    Pyomyositis is a pyogenic infection of the skeletal muscle which can cause significant morbidity and mortality if not properly treated. Diabetes mellitus (DM) is a well recognized risk factor for development of pyomyositis. The usual causative pathogen of pyomyositis in diabetes mellitus is Staphylococcus aureus. Tuberculous ...

  13. Surgery in the treatment of type 2 diabetes mellitus.

    Science.gov (United States)

    Maleckas, A; Venclauskas, L; Wallenius, V; Lönroth, H; Fändriks, L

    2015-03-01

    The prevalence of diabetes is increasing worldwide, and most of the cases are type 2 diabetes mellitus. The relationship between type 2 diabetes mellitus and obesity is well established, and surgical treatment is widely used for obese patients with type 2 diabetes mellitus. The aim was to present current knowledge about the possible mechanisms responsible for glucose control after surgical procedures and to review the surgical treatment results. Medical literature was searched for the articles presenting the impact of surgical treatment on glycemic control, long-term results, and possible mechanisms of action among obese individuals with type 2 diabetes mellitus. Remission of type 2 diabetes mellitus after bariatric surgery depends on the definition of the remission used. Complete remission rate after surgery with the new criteria is lower than was considered before. Randomized controlled studies demonstrate that surgery is superior to best medical treatment for the patients with type 2 diabetes mellitus. The recurrence of type 2 diabetes mellitus after bariatric surgery is observed in up to 40% of cases with ≥ 5 years of follow-up. Despite the recurrence of type 2 diabetes mellitus in this group, better glycemic control and lower risk of macrovascular complications are present. Incretin effects on glycemic control after bariatric surgery are well described, but the role of other possible mechanisms (bile acids, microbiota, intestinal gluconeogenesis) in humans is unclear. Surgery is an effective treatment of type 2 diabetes mellitus in obese patients. The most optimal surgical procedure for the treatment of obese patients with type 2 diabetes mellitus is still to be established. More research is needed to explore the mechanisms of glycemic control after bariatric surgery. © The Finnish Surgical Society 2015.

  14. Buccal alterations in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Negrato Carlos

    2010-01-01

    Full Text Available Abstract Long standing hyperglycaemia besides damaging the kidneys, eyes, nerves, blood vessels, heart, can also impair the function of the salivary glands leading to a reduction in the salivary flow. When salivary flow decreases, as a consequence of an acute hyperglycaemia, many buccal or oral alterations can occur such as: a increased concentration of mucin and glucose; b impaired production and/or action of many antimicrobial factors; c absence of a metalloprotein called gustin, that contains zinc and is responsible for the constant maturation of taste papillae; d bad taste; e oral candidiasis f increased cells exfoliation after contact, because of poor lubrication; g increased proliferation of pathogenic microorganisms; h coated tongue; i halitosis; and many others may occur as a consequence of chronic hyperglycaemia: a tongue alterations, generally a burning mouth; b periodontal disease; c white spots due to demineralization in the teeth; d caries; e delayed healing of wounds; f greater tendency to infections; g lichen planus; h mucosa ulcerations. Buccal alterations found in diabetic patients, although not specific of this disease, have its incidence and progression increased when an inadequate glycaemic control is present.

  15. Buccal alterations in diabetes mellitus.

    Science.gov (United States)

    Negrato, Carlos Antonio; Tarzia, Olinda

    2010-01-15

    Long standing hyperglycaemia besides damaging the kidneys, eyes, nerves, blood vessels, heart, can also impair the function of the salivary glands leading to a reduction in the salivary flow. When salivary flow decreases, as a consequence of an acute hyperglycaemia, many buccal or oral alterations can occur such as: a) increased concentration of mucin and glucose; b) impaired production and/or action of many antimicrobial factors; c) absence of a metalloprotein called gustin, that contains zinc and is responsible for the constant maturation of taste papillae; d) bad taste; e) oral candidiasis f) increased cells exfoliation after contact, because of poor lubrication; g) increased proliferation of pathogenic microorganisms; h) coated tongue; i) halitosis; and many others may occur as a consequence of chronic hyperglycaemia: a) tongue alterations, generally a burning mouth; b) periodontal disease; c) white spots due to demineralization in the teeth; d) caries; e) delayed healing of wounds; f) greater tendency to infections; g) lichen planus; h) mucosa ulcerations. Buccal alterations found in diabetic patients, although not specific of this disease, have its incidence and progression increased when an inadequate glycaemic control is present.

  16. Nutritional strategies in type 2 diabetes mellitus.

    Science.gov (United States)

    Davis, Nichola; Forbes, Bernice; Wylie-Rosett, Judith

    2009-06-01

    Weight loss is a key goal in the management of patients with type 2 diabetes mellitus. There are conflicting weight-loss strategies, including low-carbohydrate diets, low glycemic-index diets, low-fat vegan diets, conventional low-fat diets, and high-protein and high-monounsaturated fat diets. There is no evidence to suggest that 1 nutritional strategy is clearly the best. The most successful strategy is one that the patient can adopt and follow in the long term. (c) 2009 Mount Sinai School of Medicine.

  17. Linkage Between Periodontal Disease and Diabetes Mellitus

    DEFF Research Database (Denmark)

    Holmstrup, Palle; Flyvbjerg, Allan

    2016-01-01

    The past decades have significantly widened the perspectives of the chronic oral infectious disease known as periodontitis. The disease is regarded as a bacterial infection resulting in low-grade inflammation of the periodontal tissues, and both the associated release of pro-inflammatory mediators...... and the presence of bacteria in the periodontal pockets, which, as the result of daily procedures, may spread after penetration of the vasculature, are possible mediators of systemic consequences. This chapter deals with the possible association between periodontitis and diabetes mellitus which is believed...

  18. Momordica charantia for type 2 diabetes mellitus.

    Science.gov (United States)

    Ooi, Cheow Peng; Yassin, Zaitun; Hamid, Tengku-Aizan

    2012-08-15

    Momordica charantia (bitter gourd) is not only a nutritious vegetable but it is also used in traditional medical practices to treat type 2 diabetes mellitus. Experimental studies with animals and humans suggested that the vegetable has a possible role in glycaemic control. To assess the effects of mormodica charantia for type 2 diabetes mellitus. Several electronic databases were searched, among these were The Cochrane Library (Issue 1, 2012), MEDLINE, EMBASE, CINAHL, SIGLE and LILACS (all up to February 2012), combined with handsearches. No language restriction was used. We included randomised controlled trials (RCTs) that compared momordica charantia with placebo or a control intervention, with or without pharmacological or non-pharmacological interventions. Two authors independently extracted data. Risk of bias of the trials was evaluated using the parameters of randomisation, allocation concealment, blinding, completeness of outcome data, selective reporting and other potential sources of bias. A meta-analysis was not performed given the quality of data and the variability of preparations of momordica charantia used in the interventions (no similar preparation was tested twice). Four randomised controlled trials with up to three months duration and investigating 479 participants met the inclusion criteria. Risk of bias of these trials (only two studies were published as a full peer-reviewed publication) was generally high. Two RCTs compared the effects of preparations from different parts of the momordica charantia plant with placebo on glycaemic control in type 2 diabetes mellitus. There was no statistically significant difference in the glycaemic control with momordica charantia preparations compared to placebo. When momordica charantia was compared to metformin or glibenclamide, there was also no significant change in reliable parameters of glycaemic control. No serious adverse effects were reported in any trial. No trial investigated death from any cause

  19. [Impact of diabetes mellitus on driving safety].

    Science.gov (United States)

    Ekoé, J M; Laberge-Nadeau, C; Ghadirian, P; Hamet, P

    1991-01-01

    Driving ability is controlled by specific regulations. Therefore disabled individuals or those with certain chronic diseases may be affected by these regulations. These latter are based on assumption that the existence and the nature of certain diseases may cause particular hazard; and this could be prevented by introducing certain driving regulations. This hypothesis has not been tested properly, considering the proposed and suspected risk factors. Diabetes mellitus is a good example of the interested medical condition in this field. Review of the literature do not provide adequate information to allow us to conclude whether the insulin treated diabetic person is at higher risk to develop traffic accident, compared with non diabetic individual; and there is no definite explanation whether hypoglycaemia play a causative role in the etiology of traffic accident among insulin treated diabetics. Perhaps the lack of knowledge in this field is due to use of non-standardized methodologies and small sample size studies which make the comparisons difficult. The existing regulations in different countries are based on empirical knowledge and common sense. This often leads to conflictual situations and apparently discriminatory decisions regarding diabetics. Further comparative and prospective studies are needed.

  20. Technology in the management of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Ranjit Unnikrishnan

    2018-01-01

    Full Text Available The explosive increase in the prevalence of diabetes mellitus in resource-strapped regions of the world demands innovative solutions in healthcare. Advances in information technology, diagnostics and food technology have the potential to make diagnosis and treatment of diabetes simpler, cost-effective and patient-friendly. Newer methods of glucose testing such as the ambulatory glucose profile promise to make clinical decision-making easier and more robust. More advanced modes of insulin delivery are likely to help larger proportions of patients achieve their glycaemic goals with minimal risk of hypoglycaemia. Use of telemedicine and electronic medical records represents a significant advance in improving delivery of diabetes care and monitoring its outcomes. Efforts are also on to harness the wide penetrance of mobile phones in spreading awareness about diabetes and its prevention as well as in screening for retinopathy. Advances in technology also promise to favourably alter the food habits of the population, with the advent of the novel high-fibre white rice being a case in point. This narrative review aims to discuss some of the ways in which emerging technologies are making diabetes monitoring and treatment easier, more effective and pleasant for the patient.

  1. Periodontitis as a possible early sign of diabetes mellitus

    NARCIS (Netherlands)

    Teeuw, Wijnand J.; Kosho, Madeline X. F.; Poland, Dennis C. W.; Gerdes, Victor E. A.; Loos, Bruno G.

    2017-01-01

    The early diagnosis of (pre)diabetes mellitus is essential for the prevention of diabetes complications. It has been suggested that gum disease (periodontitis) might be an early complication of diabetes and may be a useful risk indicator for diabetes screening. Therefore, a dental office could be a

  2. Animal models of obesity and diabetes mellitus

    DEFF Research Database (Denmark)

    Kleinert, Maximilian; Clemmensen, Christoffer; Hofmann, Susanna M

    2018-01-01

    More than one-third of the worldwide population is overweight or obese and therefore at risk of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more potent therapeutics are urgently required. This necessitates the continued use of animal models to discover......, validate and optimize novel therapeutics for their safe use in humans. In order to improve the transition from bench to bedside, researchers must not only carefully select the appropriate model but also draw the right conclusions. In this Review, we consolidate the key information on the currently...... available animal models of obesity and diabetes and highlight the advantages, limitations and important caveats of each of these models....

  3. EPIDEMIOLOGICAL STUDY OF DIABETIC RETINOPATHY IN DIABETES MELLITUS PATIENTS IN TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Bhaskar

    2016-02-01

    Full Text Available OBJECTIVE The study objective was to examine the effect of glycaemic control and variations on the incidence and progression of diabetic retinopathy (DR among the diabetes mellitus patients visiting Medicine and Ophthalmology OPD Sapthagiri Medical college, Bangalore. MATERIALS AND METHODS 10 patients with type 1 diabetes mellitus, and 70 persons with type 2 diabetes mellitus, visiting the Medicine OPD of Sapthagiri Medical College and referred to Ophthalmology department of the above to detect the Diabetic Retinopathy changes in a diabetes mellitus management programme conducted for 3 months in Bangalore, participated in the study. Patients who were followed up for 6 months the same above were also included in the study. Analyses were conducted to assess the relationship between the risk factors, incidence and progression of Diabetic Retinopathy among Diabetes Mellitus patients and management. MAIN OUTCOME MEASURES To determine the risk factors associated with it, stage of retinopathy diagnosed at presentation, management of it, and final visual outcome. The prevention is by strict glycaemic control, prompt use of anti-diabetic drugs and regular exercises. These included age and gender-adjusted prevalence of diabetes and diabetic retinopathy, 1 and correlation of prevalence with history-based risk factors. RESULTS The three months cumulative incidence of DR was 58 %in type I diabetes mellitus and 42 % among type II Diabetes mellitus. After controlling for known risk factors for DR,1 a high baseline haemoglobin A1c (HbA1c, ethnicity, age, type of diabetes mellitus, duration were associated with the incidence of referable DR in patients with type 1 and type 2 diabetes mellitus. The age- and gender-adjusted prevalence rate of diabetes in urban Bangalore 28.2% (95% confidence interval [CI], and the prevalence of diabetic retinopathy in general population was 3.5% (95% CI. The prevalence of diabetic retinopathy in the population with diabetes

  4. Diabetes mellitus tipo 2 y resistencia a la insulina

    Directory of Open Access Journals (Sweden)

    Enrique Cipriani-Thorne

    2010-07-01

    Full Text Available Se analizó la literatura de los últimos 15 años para poder objetivar los temas que son materia de esta comunicación. En primer lugar se analiza en qué consiste el llamado Síndrome Metabólico, sus características; a continuación se resume la historia natural de la Diabetes Mellitus tipo II y su patogenia. Se revisa la importancia de la resistencia a la insulina en el músculo estriado principal órgano de combustión de la glucosa y el factor mitocondrial de la resistencia a la insulina. Se analiza además la importancia de resistencia a la insulina con respecto al metabolismo del hígado y en particular a las alteraciones del metabolismo del colesterol y de los triglicéridos. Se hace un comentario extenso de cómo así la Diabetes Mellitus Tipo II es considerada en la actualidad como una enfermedad de origen inflamatorio y por último se discuten las consecuencias de la hiperinsulinemia, dado que el exceso de insulina es producido por el bloqueo en la línea metabólica de su acción más no en su línea de producir proliferación tisular.(Rev Med Hered 2010;21:160-170.

  5. A study on the cutaneous manifestations of diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Neerja Puri

    2012-04-01

    Full Text Available The cutaneous manifestations of diabetes mellitus are varied. We conducted a study of fifty patients having diabetes mellitus coming from the department of dermatology and medicine. The commonest cutaneous feature of diabetes were pyodermas seen in 40% patients, dermatophytosis seen in 36% patients, pruritis diabetic thick skin seen in 20 % patients, diabetic dermopathy seen in 16% patients, diabetic bulla and rubeosis seen in 8% patients each and meralgia paraesthetica and diabetic foot seen in 4% patients each. About the associations of diabetes mellitus, achrchordons were seen in 8% patients, vitiligo and perforating dermatoses were seen in 6% patients each, granuloma annulare, eruptive xanthomas, acanthosis nigricans, necrobiosis lipoidica and oral lichen planus were seen in 4 % patients each and xanthelasma was seen in 2% patients.

  6. Controle inadequado da pressão arterial em pacientes com diabete melito tipo 2 Control inadecuado de la presión arterial en pacientes con diabetes melito tipo 2 Inadequate blood pressure control in patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Lana C. Pinto

    2010-05-01

    10,1 años (el 46% hombre, 80% blanco y la duración del DM, 14,8 ± 9,5 años. Del total de pacientes, el 17% expresaba valores ideales de PA, el 22% regular y el 61% inadecuados. Los pacientes con control inadecuado de la PA expresaban mayor duración del DM, cintura abdominal y glucemia de ayuno. Las demás variables se asemejaron en los tres grupos. CONCLUSIÓN: La mayoría de los pacientes evaluados presentó control inadecuado de la PA. Valores más elevados de PA están asociados a un perfil clínico adverso, representado por mayor duración del DM, obesidad abdominal, mayor glucemia de ayuno y complicaciones crónicas del DM.BACKGROUND: There is evidence indicating that blood pressure control is more effective in reducing macrovascular complications of diabetes mellitus (DM than glycemic control. However, the reduction in BP to levels recommended by international guidelines is difficult in clinical practice. OBJECTIVE: To assess the percentage of patients with both type 2 diabetes and hypertension (HBP assisted in a tertiary hospital with adequate blood pressure control and to determine the clinical and laboratory factors related. METHODS: Cross-sectional study with 348 patients with type 2 diabetes and hypertension assisted in the outpatient clinic of Endocrinology, Hospital de Clínicas de Porto Alegre. Patients underwent history assessment, physical examination, with measurement of blood pressure (BP, and samples were collected from blood and urine for laboratory analysis. Patients were divided into 3 three groups: optimal (< 130/80 mmHg, regular (130-139/80-89 mmHg or inadequate blood pressure control (≥ 140/90 mmHg. RESULTS: The mean age was 61.2 ± 10.1 years (46% men, 80% white and DM duration, 14.8 ± 9.5 years. Eighteen per cent of the patients studied, 17% of patients had optimal BP value, 22% regular BP value and 61% inadequate BP value. Patients with inadequate BP control had longer diabetes duration, waist circumference and fasting glucose. The

  7. Diabetes mellitus and impairment of intestinal barier function

    OpenAIRE

    Hoffmanová, Iva

    2015-01-01

    Introduction: Impairment of intestinal barrier function is involved in pathogenesis of immune mediated diseases (such as type 1 diabetes mellitus or celiac disease) and metabolic diseases (such as type 2 diabetes mellitus). Aims of study: The first aim was to analyze impairment of mucosal part of intestinal barrier in both type of diabetes and to describe differences when compared to celiac disease, which is a typical condition associated with impairment of intestinal barrier function. The se...

  8. Does 'Honeymoon period' exist in type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    SM Ashrafuzzaman

    2008-07-01

    Full Text Available Temporary remission of type 1 diabetes mellitus (T1DM occurs following initiation of insulin therapy. This period of temporary remission without insulin therapy is called ‘honeymoon period’. But no such temporary remission usually occurs in type 2 diabetes (T2DM. We report here two cases of type 2 diabetes mellitus where such honey moon period was observed. Ibrahim Med. Coll. J. 2008; 2(2: 67-69

  9. Hypertension and Diabetes Mellitus: Coprediction and Time Trajectories.

    Science.gov (United States)

    Tsimihodimos, Vasilis; Gonzalez-Villalpando, Clicerio; Meigs, James B; Ferrannini, Ele

    2018-03-01

    Type 2 diabetes mellitus and hypertension overlap in the population. In many subjects, development of diabetes mellitus is characterized by a relatively rapid increase in plasma glucose values. Whether a similar phenomenon occurs during the development of hypertension is not known. We analyzed the pattern of blood pressure (BP) changes during the development of hypertension in patients with or without diabetes mellitus using data from the MCDS (Mexico City Diabetes Study; a population-based study of diabetes mellitus in Hispanic whites) and in the FOS (Framingham Offspring Study, a community-based study in non-Hispanic whites) during a 7-year follow-up. Diabetes mellitus at baseline was a significant predictor of incident hypertension (in FOS, odds ratio, 3.14; 95% confidence interval, 2.17-4.54) independently of sex, age, body mass index, and familial diabetes mellitus. Conversely, hypertension at baseline was an independent predictor of incident diabetes mellitus (in FOS, odds ratio, 3.33; 95% CI, 2.50-4.44). In >60% of the converters, progression from normotension to hypertension was characterized by a steep increase in BP values, averaging 20 mm Hg for systolic BP within 3.5 years (in MCDS). In comparison with the nonconverters group, hypertension and diabetes mellitus converters shared a metabolic syndrome phenotype (hyperinsulinemia, higher body mass index, waist girth, BP, heart rate and pulse pressure, and dyslipidemia). Overall, results were similar in the 2 ethnic groups. We conclude that (1) development of hypertension and diabetes mellitus track each other over time, (2) transition from normotension to hypertension is characterized by a sharp increase in BP values, and (3) insulin resistance is one common feature of both prediabetes and prehypertension and an antecedent of progression to 2 respective disease states. © 2018 American Heart Association, Inc.

  10. Diabetes mellitus: fatores de risco em trabalhadores de enfermagem Diabetes mellitus: factores de riesgo en trabajadores de enfermería Diabetes mellitus: risk factors for nursing workers

    Directory of Open Access Journals (Sweden)

    Rosa Maria Fernandes Vilarinho

    2010-01-01

    Full Text Available OBJETIVOS: Identificar os fatores de risco para o diabetes mellitus tipo 2, entre trabalhadores de enfermagem do Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione. MÉTODOS: Estudo transversal com aplicação de dois instrumentos de coleta de dados que incluíram questões abertas e fechadas relativas ao estado de saúde e estilo de vida de 100 trabalhadores de enfermagem dessa instituição de saúde. Foram ainda verificados dados de natureza bioquímica e antropométrica. RESULTADOS: Os resultados confirmaram a ocorrência de importantes fatores de risco de natureza reversível, destacando-se o sedentarismo e a obesidade. CONCLUSÃO: Considera-se a importância do desenvolvimento de ações visando a promoção da saúde com enfoque na prevenção de doenças crônicas, a serem realizadas no próprio ambiente de trabalho.OBJETIVOS: Identificar los factores de riesgo para la diabetes mellitus tipo 2 entre trabajadores de enfermería del Instituto Estatal de Diabetes e Endocrinología Luiz Capriglione. MÉTODOS: Se trata de un estudio transversal con aplicación de dos instrumentos de recolección de datos que incluyeron preguntas abiertas y cerradas relacionadas al estado de salud y estilo de vida de 100 trabajadores de enfermería de esa institución de salud. Fueron también verificados datos de naturaleza bioquímica y antropométrica. RESULTADOS: Los resultados confirmaron la ocurrencia de importantes factores de riesgo de naturaleza reversible, destacándose el sedentarismo y la obesidad. CONCLUSIÓN: Se considera importante desarrollar acciones que tengan por objetivo la promoción de la salude con enfoque en la prevención de enfermedades crónicas, a ser realizadas en el propio ambiente de trabajo.OBJECTIVES: To identify risk factors for type 2 diabetes mellitus, among nursing workers at the State Institute of Diabetes and Endocrinology Luiz Capriglione. METHODS: This is a cross-sectional study in which were applied two

  11. Uso de la metformina en la diabetes mellitus tipo II Use of metformin to treat type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Yohana Salazar ÁLvarez

    2011-03-01

    Full Text Available Metformina es una biguanida eficaz en el control metabólico de la diabetes mellitus tipo II, no insulinodependiente cuando el control dietético falla. Dada su probada eficacia y actual accesibilidad en el mercado de medicamentos en Cuba, para ser utilizada a nivel primario de atención no solo en pacientes sintomáticos sino en la población en riesgo, se presenta este artículo cuyo propósito es actualizar a los especialistas de Medicina General Integral y Medicina Interna acerca de aspectos de interés relacionados con este medicamento, como: interacciones medicamentosas, enfermedades concomitantes, la biotransformación de la droga y los posibles efectos adversos que se pueden asociar a su uso. Se presentan consideraciones finales acerca del uso de esta droga.Metformin is an effective biguanide for the metabolic control of non-insulin dependent type 2 diabetes mellitus when the dietary control fails. Given its proven efficacy and present accessibility in the pharmaceutical market in Cuba -to be used at primary health care not only in symptomatic patients but in the population at risk-this article was presented to update the knowledge of the Family Medicine and Internal Medicine specialists about interesting aspects related to this drug, i.e, drug interactions, concomitant diseases, drug biotransformation and the possible adverse effects associated to its use. Final remarks on the use of this drug were stated.

  12. Modification of the metabolic parameters and microalbuminuria in patients with diabetes mellitus type 2 treated with acarbose

    OpenAIRE

    González Sarmiento, E.; Ergueta Martín, P.; Fernández Martínez, I.; Hinojosa Mena-Bernal, M.C.; Zurro Muñoz, I.; Zurro Hernández, J.

    2001-01-01

    Objetivo: Determinar la influencia de la acarbosa en la microalbuminuria y parámetros metabólicos en pacientes con diabetes mellitus tipo 2. Material y métodos: Hemos estudiado 92 pacientes con diabetes tipo 2, tratados con acarbosa, sola o con insulina o antidiabéticos orales. Hemos determinado los valores de Hb A1c, colesterol total, colesterol HDL, colesterol LDL, triglicéridos y microalbuminuria, antes y después del tratamiento con acarbosa. Resultados: Los pacientes presentaron de forma ...

  13. Uso de la metformina en la diabetes mellitus tipo II

    Directory of Open Access Journals (Sweden)

    Yohana Salazar ÁLvarez

    2011-03-01

    Full Text Available Metformina es una biguanida eficaz en el control metabólico de la diabetes mellitus tipo II, no insulinodependiente cuando el control dietético falla. Dada su probada eficacia y actual accesibilidad en el mercado de medicamentos en Cuba, para ser utilizada a nivel primario de atención no solo en pacientes sintomáticos sino en la población en riesgo, se presenta este artículo cuyo propósito es actualizar a los especialistas de Medicina General Integral y Medicina Interna acerca de aspectos de interés relacionados con este medicamento, como: interacciones medicamentosas, enfermedades concomitantes, la biotransformación de la droga y los posibles efectos adversos que se pueden asociar a su uso. Se presentan consideraciones finales acerca del uso de esta droga.

  14. Neonatal Hyperglycemia due to Transient Neonatal Diabetes Mellitus in Puerto Rico

    OpenAIRE

    Fargas-Berríos, N.; García-Fragoso, L.; García-García, I.; Valcárcel, M.

    2015-01-01

    Neonatal hyperglycemia is a metabolic disorder found in the neonatal intensive care units. Neonatal diabetes mellitus (NDM) is a very uncommon cause of hyperglycemia in the newborn, occurring in 1 in every 400,000 births. There are two subtypes of neonatal diabetes mellitus: permanent neonatal diabetes mellitus (PNDM) and transient neonatal diabetes mellitus (TNDM). We describe a term, small for gestational age, female neonate with transient neonatal diabetes mellitus who presented with poor ...

  15. Gestational diabetes mellitus: Non-insulin management

    Directory of Open Access Journals (Sweden)

    Navneet Magon

    2011-01-01

    Full Text Available Gestational diabetes mellitus (GDM complicates a substantial number of pregnancies. There is consensus that in patients of GDM, excellent blood glucose control, with diet and, when necessary, oral hypoglycemics and insulin results in improved perinatal outcomes, and appreciably reduces the probability of serious neonatal morbidity compared with routine prenatal care. Goals of metabolic management of a pregnancy complicated with GDM have to balance the needs of a healthy pregnancy with the requirements to control glucose level. Medical nutrition therapy is the cornerstone of therapy for women with GDM. Surveillance with daily self-monitoring of blood glucose has been found to help guide management in a much better way than blood glucose checking in labs and clinics, which tends to be less frequent. Historically, insulin has been the therapeutic agent of choice for controlling hyperglycemia in pregnant women. However, difficulty in medication administration with multiple daily injections, potential for hypoglycemia, and increase in appetite and weight make this therapeutic option cumbersome for many pregnant patients. Use of oral hypogycemic agents (OHAs in pregnancy has opened new vistas for GDM management. At present, there is a growing acceptance of glyburide (glibenclamide use as the primary therapy for GDM. Glyburide and metformin have been found to be safe, effective and economical for the treatment of gestational diabetes. Insulin, however, still has an important role to play in GDM. GDM is a window of opportunity, which needs to be seized, for prevention of diabetes in future life. Goal of our educational programs should be not only to improve pregnancy outcomes but also to promote healthy lifestyle changes for the mother that will last long after delivery. Team effort on part of obstetricians and endocrinologists is required to make " the diabetes capital of the world" into " the diabetes care capital of the world".

  16. Correlation between glycemic excursion by CGMS and diabetic retinopathy among Type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Pu Li; Ji Ning; Zhu Wei

    2011-01-01

    Objective: To investigate correlation between glycemic excursion by CGMS and diabetic retinopathy among type 2 diabetes mellitus. Methods: Used continuous glucose monitoring system (CGMS) to monitoring glycemic excursion within a day of twenty four patients with type 2 diabetes mellitus, and inspect fundus photography, correlation was analyzed. Results: Glycemic excursion might reveal the risk for diabetic retinopathy better than HbA1c does. Conclusion: Diabetic retinopathy may correlate with glycemic excursion. (authors)

  17. Aldose reductase, oxidative stress and diabetic mellitus

    Directory of Open Access Journals (Sweden)

    Waiho eTang

    2012-05-01

    Full Text Available Diabetes mellitus (DM is a complex metabolic disorder arising from lack of insulin production or insulin resistance 1. DM is a leading cause of morbidity and mortality in the developed world, particularly from vascular complications such as atherothrombosis in the coronary vessels. Aldose reductase (AR [ALR2; EC 1.1.1.21], a key enzyme in the polyol pathway, catalyzes NADPH-dependent reduction of glucose to sorbitol, leading to excessive accumulation of intracellular reactive oxygen species (ROS in various tissues of DM including the heart, vasculature, neurons, eyes and kidneys. As an example, hyperglycemia through such polyol pathway induced oxidative stress, may have dual heart actions, on coronary blood vessel (atherothrombosis and myocardium (heart failure leading to severe morbidity and mortality (reviewed in 2. In cells cultured under high glucose conditions, many studies have demonstrated similar AR-dependent increases in ROS production, confirming AR as an important factor for the pathogenesis of many diabetic complications. Moreover, recent studies have shown that AR inhibitors may be able to prevent or delay the onset of cardiovascular complications such as ischemia/reperfusion injury, atherosclerosis and atherothrombosis. In this review, we will focus on describing pivotal roles of AR in the pathogenesis of cardiovascular diseases as well as other diabetic complications, and the potential use of AR inhibitors as an emerging therapeutic strategy in preventing DM complications.

  18. Anti-glucagon antibodies in diabetes mellitus

    Energy Technology Data Exchange (ETDEWEB)

    Gergely, A; Koranyi, L; Halmos, T; Zsombok, M; Peterfy, F; Csizer, Z; Salamon, F; Tako, J

    1973-01-01

    Anti-insulin antibodies appear in the sera of patients treated with insulin lastingly. A high anti-insulin antibody level results in the development of insulin resistance. Most of the insulin preparations available on the market contain also glucagon as an impurity. It was therefore to be expected that in part of the patients, who had been treated with insulin lastingly, antibodies would be produced also against glucagon, and the presence of these was actually demonstrated. It is to be assumed that the anti-glucagon antibodies play a role in the pathomechanism of diabetes mellitus, mainly in its labile form. The possible presence of anti-glucagon antibodies must be taken into account when the glucagon concentration in the sera of diabetics is to be determined by means of radioimmunoassay (RIA). The specific antibodies in the serum give false results in the quantitative determination of glucagon. We have tested the sera of 10 diabetics who had been treated with insulin for at least 6 years. All patients were given protamine zinc and crystalline insulin preparations.

  19. Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus

    Science.gov (United States)

    Moon, Joon Ho; Kwak, Soo Heon; Jang, Hak C.

    2017-01-01

    Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold higher risk of developing postpartum diabetes compared with women without GDM. Various risk factors for postpartum diabetes have been identified, including maternal age, glucose levels in pregnancy, family history of diabetes, pre-pregnancy and postpartum body mass index, dietary patterns, physical activity, and breastfeeding. Genetic studies revealed that GDM shares common genetic variants with type 2 diabetes. A number of lifestyle interventional trials that aimed to ameliorate modifiable risk factors, including diet, exercise, and breastfeeding, succeeded in reducing the incidence of postpartum diabetes, weight retention, and other obesity-related morbidities. The present review summarizes the findings of previous studies on the incidence and risk factors of postpartum diabetes and discusses recent lifestyle interventional trials that attempted to prevent postpartum diabetes. PMID:28049284

  20. Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.

    Science.gov (United States)

    Moon, Joon Ho; Kwak, Soo Heon; Jang, Hak C

    2017-01-01

    Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold higher risk of developing postpartum diabetes compared with women without GDM. Various risk factors for postpartum diabetes have been identified, including maternal age, glucose levels in pregnancy, family history of diabetes, pre-pregnancy and postpartum body mass index, dietary patterns, physical activity, and breastfeeding. Genetic studies revealed that GDM shares common genetic variants with type 2 diabetes. A number of lifestyle interventional trials that aimed to ameliorate modifiable risk factors, including diet, exercise, and breastfeeding, succeeded in reducing the incidence of postpartum diabetes, weight retention, and other obesity-related morbidities. The present review summarizes the findings of previous studies on the incidence and risk factors of postpartum diabetes and discusses recent lifestyle interventional trials that attempted to prevent postpartum diabetes.

  1. Association of diabetes mellitus and dementia : The Rotterdam study

    NARCIS (Netherlands)

    Ott, A; Stolk, RP; Hofman, A; vanHarskamp, F; Grobbee, DE; Breteler, MMB

    1996-01-01

    Dementia and non-insulin-dependent diabetes mellitus (NIDDM) are highly prevalent disorders in the elderly. Diabetes has repeatedly been reported to affect cognition, but its relation with dementia is uncertain. We therefore studied the association between diabetes and dementia in the Rotterdam

  2. Diabetes mellitus is strongly associated with tuberculosis in Indonesia.

    NARCIS (Netherlands)

    Alisjahbana, B.; Crevel, R. van; Sahiratmadja, E.; Heijer, M. den; Maya, A.; Istriana, E.; Danusantoso, H.; Ottenhoff, T.H.; Nelwan, R.H.; Meer, J.W.M. van der

    2006-01-01

    SETTING: Diabetes mellitus is a known risk factor for tuberculosis (TB), but no studies have been reported from South-East Asia, which has a high burden of TB and a rapidly growing prevalence of diabetes. OBJECTIVE: To examine if and to what extent diabetes is associated with an increased risk of TB

  3. Rehabilitation of tendon problems in patients with diabetes mellitus

    NARCIS (Netherlands)

    Rees, Jonathan; Gaida, Jamie E.; Silbernagel, Karin Grävare; Zwerver, Johannes; Anthony, Joseph S.; Scott, Alex; Ackermann, PW; Hart, DA

    2016-01-01

    Exercise is crucial in the management of diabetes mellitus and its associated complications. However, individuals with diabetes have a heightened risk of musculoskeletal problems, including tendon pathologies. Diabetes has a significant impact on the function of tendons due to the accumulation of

  4. 78 FR 65031 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-2013-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 19 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 19 individuals and requested comments from the...

  5. 78 FR 76398 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0188] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 29 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 29 individuals and requested comments from the...

  6. 78 FR 7855 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-04

    ...-2012-0349] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 12 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 12 individuals and requested comments from the...

  7. 78 FR 60014 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-30

    ...-2013-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 16 individuals from its rule prohibiting persons with insulin-treated diabetes... of Federal diabetes exemption applications from 16 individuals and requested comments from the public...

  8. 78 FR 50140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-16

    ...-2013-0019] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 24 individuals from its rule prohibiting persons with insulin-treated diabetes... of Federal diabetes exemption applications from 24 individuals and requested comments from the public...

  9. 78 FR 1926 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-2012-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 12 individuals from its rule prohibiting persons with insulin-treated diabetes....pdf . Background On October 31, 2012, FMCSA published a notice of receipt of Federal diabetes...

  10. 78 FR 76397 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0187] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 16 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 16 individuals and requested comments from the...

  11. Circulating Adipokine levels in Type 2 Diabetes Mellitus in Lagos ...

    African Journals Online (AJOL)

    Objective: This study was undertaken with the aim of investigating adipokine levels in the Type 2 Diabetes Mellitus. Methods: This is a cross sectional study conducted in Lagos University Teaching Hospital (LUTH), a-700 bed tertiary hospital centre in Lagos, Nigeria. 53 diabetic subjects and 27 non-diabetic controls with ...

  12. Cardiovascular burden of diabetes mellitus: a review | Dodiyi ...

    African Journals Online (AJOL)

    Background: The incidence of diabetes mellitus (DM) is rapidly on the increase worldwide and is gradually becoming a major public health problem for developing nations. Diabetes in all its forms is one of the main cardiovascular risk factors. Cardiovascular complications are a leading cause of death in diabetic patients ...

  13. Current Trends In The Management Of Diabetes Mellitus: The ...

    African Journals Online (AJOL)

    Diabetes mellitus (DM) is a chronic, non-communicable disease with concomitant oral manifestations that impact on dental care. Approximately 40-80 persons in 2,000 adult population visiting dental practice are diabetic and about half are unaware of their condition. The average dentist attends to over 100 diabetic patients ...

  14. Prevalence of hypertension amongst persons with diabetes mellitus ...

    African Journals Online (AJOL)

    Objective: To determine the prevalence of hypertension amongst persons with diabetes mellitus (DM) in Benin city. Materials and Methods: Four hundred and fifty diabetic subjects were evaluated for hypertension by measuring their blood pressure using a sphygmomanometer at the diabetes clinics of the University of Benin ...

  15. Diabetes mellitus, diabetes insipidus, optic atrophy, and deafness: A case of Wolfram (DIDMOAD) syndrome.

    Science.gov (United States)

    Maleki, Nasrollah; Bashardoust, Bahman; Zakeri, Anahita; Salehifar, Azita; Tavosi, Zahra

    2015-01-01

    To report a case of Wolfram syndrome (WS) characterized by diabetes mellitus, diabetes insipidus, progressive optic atrophy, and deafness. A 19-year-old female patient, a known case of diabetes mellitus type I from six years before, presented with progressive vision loss since four years earlier. On fundoscopic examination, she had bilateral optic atrophy without diabetic retinopathy. The patient also had diabetes insipidus, neurosensory deafness, and neurogenic bladder. WS should be considered a differential diagnosis in patients with diabetes mellitus who present with optic atrophy, and it is necessary to perform a hearing test as well as collecting 24-h urine output.

  16. Diabetes mellitus in childhood cystic fibrosis.

    LENUS (Irish Health Repository)

    Rauf, F

    2012-02-03

    Since 1984, five patients in the cystic fibrosis (CF) clinic at Cork Regional Hospital have developed diabetes mellitus (DM) and were treated with Insulin. None had received systemic corticosteroids but two had high calorie naso-gastric feeding regimes. Two died from lung disease. A fifteen year old boy developed bilateral cataracts. In nine other paediatric CF clinics in the Republic of Ireland (total: 420 patients), three patients have DM, two receiving Insulin. Abnormal glucose tolerance is becoming more common in CF as patients survive longer. The possible role of corticosteroid treatment and intensive carbohydrate feeding regimes in development of glucose intolerance must be considered. DM in CF differs from the usual childhood DM. Regular screening and early Insulin supplementation may be beneficial.

  17. Lixisenatide for type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    Christensen, Mikkel; Knop, Filip K; Vilsbøll, Tina

    2011-01-01

    Introduction: Type 2 diabetes mellitus (T2DM) is an increasing health problem worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists are an expanding drug class that target several of the pathophysiological traits of T2DM. Lixisenatide is a GLP-1 receptor agonist in development for once......-daily treatment of T2DM. Areas covered: Pharmacological, preclinical and clinical evidence demonstrating the applicability of lixisenatide for the treatment of T2DM are reviewed. Available data and pending clinical development are summarized, critically appraised and compared to competitor drugs. The most...... relevant papers and meeting abstracts published up to November 2010 are used as sources for this review. Expert opinion: Efficacy and safety in T2DM are demonstrated with lixisenatide in monotherapy and in combination with metformin. However, limited data with the intended once-daily 20 µg subcutaneous...

  18. DIABETES MELLITUS AND BELL’S PALSY IN IRANIAN POPULATION

    Directory of Open Access Journals (Sweden)

    A. R Karimi-Yazdi

    2008-08-01

    Full Text Available "nDuring last decades many researchers have focused on the conditions associated with Bell's palsy including diabetes mellitus, hypertension, and viral infections. This study was performed to evaluate correlation of diabetes mellitus and Bell's palsy and some relevant features not discussed in the literature in an Iranian population. The presence of diabetes mellitus was evaluated in a total number of 275 subjects (75 patients with Bell's palsy and 200 control subjects. Diabetes mellitus was noted in 10 (13.3% patients with Bell's palsy among which 6 case were diagnosed as new cases of diabetes. Previous history of Bell's palsy was present in 10.67% of the subjects with Bell's palsy. Symptoms of other cranial nerves revealed higher figures in Bell's palsy patients with underlying diabetes. Such studies in developing countries may reveal some unknown features of the disease. This study confirms the correlation of diabetes mellitus and Bell's palsy for the first time in an Iranian population. The results also suggest that diabetic patients with Bell's palsy suffer from more cranial nerve symptoms. We offer screening tests of diabetes as a routine process in the management of Bell's palsy especially in developing countries.

  19. Diabetes Mellitus Coding Training for Family Practice Residents.

    Science.gov (United States)

    Urse, Geraldine N

    2015-07-01

    Although physicians regularly use numeric coding systems such as the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) to describe patient encounters, coding errors are common. One of the most complicated diagnoses to code is diabetes mellitus. The ICD-9-CM currently has 39 separate codes for diabetes mellitus; this number will be expanded to more than 50 with the introduction of ICD-10-CM in October 2015. To assess the effect of a 1-hour focused presentation on ICD-9-CM codes on diabetes mellitus coding. A 1-hour focused lecture on the correct use of diabetes mellitus codes for patient visits was presented to family practice residents at Doctors Hospital Family Practice in Columbus, Ohio. To assess resident knowledge of the topic, a pretest and posttest were given to residents before and after the lecture, respectively. Medical records of all patients with diabetes mellitus who were cared for at the hospital 6 weeks before and 6 weeks after the lecture were reviewed and compared for the use of diabetes mellitus ICD-9 codes. Eighteen residents attended the lecture and completed the pretest and posttest. The mean (SD) percentage of correct answers was 72.8% (17.1%) for the pretest and 84.4% (14.6%) for the posttest, for an improvement of 11.6 percentage points (P≤.035). The percentage of total available codes used did not substantially change from before to after the lecture, but the use of the generic ICD-9-CM code for diabetes mellitus type II controlled (250.00) declined (58 of 176 [33%] to 102 of 393 [26%]) and the use of other codes increased, indicating a greater variety in codes used after the focused lecture. After a focused lecture on diabetes mellitus coding, resident coding knowledge improved. Review of medical record data did not reveal an overall change in the number of diabetic codes used after the lecture but did reveal a greater variety in the codes used.

  20. Latest data on metabolic diseases: Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Panagiota Mitrou

    2017-01-01

    Full Text Available With such a high cost in money and human lives, diabetes mellitus (DM is a major challenge for health care systems and an obstacle to sustainable economic growth. The pathophysiological disorders of diabetes include, besides the defect in pancreatic insulin secretion and insulin resistance in peripheral tissues (liver, muscle and adipose tissue, increased lipolysis, increased glucagon secretion, impaired secretion and action of incretin hormones, increased glucose resorption by the kidney and defects in the central nervous system. The therapeutic intervention must be timely and personalized. Lifestyle interventions (diet, exercise, smoking cessation are the cornerstone of treatment. Treatment should begin with metformin unless there is a contraindication (eg renal failure or intolerance (eg, gastrointestinal disorders. If HbA1c remains off target a second or a third treatment may be added, orally (glitazone, DPP-4 inhibitors, SGLT-2 inhibitors, sulfonylurea or by injection (GLP-1 agonist or basal insulin. On failure to achieve glycemic target combinations of injectable treatments (combination of agonist GLP-1 with basal insulin, intensified insulin therapy or in some cases insulin mixtures are recommended. New treatments (weekly administered GLP-1 analogs, combination of a basal insulin / GLP-1 in one injection, SGLT-2 inhibitors, long acting basal insulins in combination with the old tried treatments (e.g. metformin, pioglitazone, inhibitors DPP-4 can contribute to human-centered and individualized management of patients with diabetes. The cardiovascular safety of antidiabetic treatment should be considered. There is a need for early diagnosis and treatment of glucose metabolism disorders during pregnancy (before 24 to 28 weeks of gestation in women at high risk for developing gestational diabetes.

  1. Diabetic Myopathy: Impact of Diabetes Mellitus on Skeletal Muscle Progenitor Cells

    Directory of Open Access Journals (Sweden)

    Donna M D'Souza

    2013-12-01

    Full Text Available Diabetes mellitus is defined as a group of metabolic diseases that are associated with the presence of a hyperglycemic state due to impairments in insulin function. While the development of each form of diabetes (Type 1 or Type 2 drastically differs, resultant pathologies often overlap. In each diabetic condition a failure to maintain healthy muscle is often observed, and is termed diabetic myopathy. This significant, but often overlooked, complication is believed to contribute to the progression of additional diabetic pathologies due to the vital importance of skeletal muscle for our physical and metabolic well-being. While studies have investigated the link between changes to skeletal muscle metabolic health following diabetes mellitus onset (particularly Type 2 diabetes mellitus, few have examined the negative impact of diabetes mellitus on the growth and reparative capacities of skeletal muscle that often coincides with disease development. Importantly, evidence is accumulating that the muscle progenitor cell population (particularly the muscle satellite cell population is also negatively affected by the diabetic environment, and as such, likely contributes to the declining skeletal muscle health observed in diabetes mellitus. In this review, we summarize the current knowledge surrounding the influence of diabetes mellitus on skeletal muscle growth and repair, with a particular emphasis on the impact of diabetes mellitus on the progenitor cell population of skeletal muscle.

  2. Does emotional stress cause type 2 diabetes mellitus?

    DEFF Research Database (Denmark)

    Pouwer, Frans; Kupper, Nina; Adriaanse, Marcel C

    2010-01-01

    and the development of type 2 diabetes mellitus. Results of longitudinal studies suggest that not only depression but also general emotional stress and anxiety, sleeping problems, anger, and hostility are associated with an increased risk for the development of type 2 diabetes. Conflicting results were found......According to the World Health Organization, approximately 220 million people worldwide have type 2 diabetes mellitus. Patients with type 2 diabetes not only have a chronic disease to cope with, they are also at increased risk for coronary heart disease, peripheral vascular disease, retinopathy......, nephropathy, and neuropathy. The exact causes of type 2 diabetes are still not clear. Since the 17th century, it has been suggested that emotional stress plays a role in the etiology of type 2 diabetes mellitus. So far, review studies have mainly focused on depression as a risk factor for the development...

  3. Diabetes mellitus during pregnancy: a study of fifty cases

    International Nuclear Information System (INIS)

    Randhawa, M. S.; Moin, S.; Shoaib, F.

    2003-01-01

    To review and critically evaluated the incidence, epidemiology, clinical pattern, diagnosis, management, complications and outcome of diabetes mellitus during pregnancy in hospital based study. Results: Total number of women delivered were 11271. Fifty cases of diabetes mellitus during pregnancy were studied. Mostly the patients were more than 30 years of age, multiparous ladies with gestational diabetes in 80% of cases, Type-II diabetes in 16% and only in 4% Type-I diabetes was reported. Insulin was required in 40% of patients. Eight women out of 50 had spontaneous miscarriage, 5 underwent preterm delivery while 36 reached term with one intrauterine death. Total number of babies delivered alive were 41. There was one stillbirth and 3 neonatal deaths. Conclusion: Management of diabetes mellitus in pregnancy involves teamwork of obstetricians, physicians and neonatologists. (author)

  4. Chemical substances as risk factors of nephropathy in diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Zofia Marchewka

    2009-12-01

    Full Text Available Although diabetes mellitus, a metabolic disease, does not fall into the group of diseases induced by toxic substances or environmental pollution, there is much evidence that some chemicals have considerable importance in its development. Exposure to substances with potential renal toxicity is especially dangerous for diabetics because it accelerates and intensifies diabetic nephropathy. This paper discusses the relationship between the xenobiotics and the development of diabetes mellitus and diabetic nephropathy with particular emphasis on those substances that causes the greatest damage to the kidneys. These are cadmium, iron, lead, arsenic, polychlorinated organic compounds, nitrogen compounds, and contrast agents. In addition, the mechanisms of diabetes mellitus induction or kidney damage by these xenobiotics are described.

  5. EPIDEMIOLOGÍA DE LA DIABETES MELLITUS EN CHILE

    Directory of Open Access Journals (Sweden)

    Jorge Sapunar Z., MD, MSC, FACP

    2016-03-01

    Finalmente, la frecuencia, morbilidad y mortalidad de la diabetes mellitus, se suman para explicar que el manejo de la enfermedad y sus complicaciones consuma el 10,2% del presupuesto en salud de Chile.

  6. Prevalence of diabetes mellitus in newly diagnosed pulmonary ...

    African Journals Online (AJOL)

    2017-09-03

    Sep 3, 2017 ... (in particular with HIV) and non-communicable diseases, such as diabetes mellitus .... non smoking while alcohol consumption was moderate, and only 2 patients .... betes: current state and future perspectives. Trop Med Int.

  7. Is there a tendency for thrombosis in gestational diabetes mellitus?

    Directory of Open Access Journals (Sweden)

    Suheyla Gorar

    2016-01-01

    Conclusions: Our findings indicate tendency to develop thrombosis in GDM similar to diabetes mellitus; but more comprehensive studies with larger sample size are needed to determine the relationship between GDM and hemostasis.

  8. Vitamin B12 Deficiency in Type 2 Diabetes Mellitus

    Directory of Open Access Journals (Sweden)

    Carlos Tavares Bello

    2017-10-01

    Conclusion: Further studies are needed to identify the risk factors for the B12 deficit. The recognition of these variables will contribute to optimize the screening and prevention of the B12 deficiency in type 2 diabetes mellitus.

  9. Phospholipid transfer protein activity and incident type 2 diabetes mellitus

    NARCIS (Netherlands)

    Abbasi, Ali; Dallinga-Thie, Geesje M.; Dullaart, Robin P. F.

    2015-01-01

    Background: The plasma activity of phospholipid transfer protein (PLTP), which has multifaceted functions in lipoprotein metabolism and in inflammatory responses, is elevated in insulin resistant conditions. We determined the association of plasma PLTP activity with incident type 2 diabetes mellitus

  10. Superimposed effect of ovariectomy on type 2 diabetes mellitus in ...

    African Journals Online (AJOL)

    Minerva K. Fahmy

    Aim: The present study investigated the overlaid effect of ovariectomy on T2DM and the possible under- ... Type 2 diabetes mellitus (T2DM) is a progressive chronic meta- ..... worsened glucose metabolism disturbance (as indicated by.

  11. Prevalence of Cutaneous Manifestations of Diabetes Mellitus: A ...

    African Journals Online (AJOL)

    Background: Diabetes mellitus is a non- communicable disease with an increasing ... condition are due to metabolic derangements or chronic degenerative complications. ... From a total of 297 skin conditions, there were 150 (50.5%) primary ...

  12. Fertility treatment and childhood type 1 diabetes mellitus

    DEFF Research Database (Denmark)

    Kettner, Laura Ozer; Matthiesen, Niels Bjerregaard; Ramlau-Hansen, Cecilia Høst

    2016-01-01

    OBJECTIVE: To investigate the association between specific types of fertility treatment and childhood type 1 diabetes mellitus. DESIGN: Nationwide birth cohort study. SETTING: Not applicable. PATIENT(S): All pregnancies resulting in a live-born singleton child in Denmark from 1995 to 2003....... INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Childhood type 1 diabetes mellitus identified from redeemed prescriptions for insulin until 2013. RESULT(S): The study included 565,116 singleton pregnancies. A total of 14,985 children were conceived by ovulation induction or intrauterine insemination......, and 8,490 children were conceived by in vitro fertilization or intracytoplasmic sperm injection. During the follow-up period, 2,011 (0.4%) children developed type 1 diabetes mellitus. The primary analyses showed no association between fertility treatment and childhood type 1 diabetes mellitus...

  13. Mechanisms of diabetes mellitus-induced bone fragility

    DEFF Research Database (Denmark)

    Napoli, Nicola; Chandran, Manju; Pierroz, Dominique D

    2017-01-01

    The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in T2DM is often normal or even slightly elevated compared with an age-matched control population. However, in both T1DM...... and T2DM, bone turnover is decreased and the bone material properties and microstructure of bone are altered; the latter particularly so when microvascular complications are present. The pathophysiological mechanisms underlying bone fragility in diabetes mellitus are complex, and include hyperglycaemia......-induced hypoglycaemia, certain antidiabetic medications with a direct effect on bone and mineral metabolism (such as thiazolidinediones), as well as an increased propensity for falls, all contribute to the increased fracture risk in patients with diabetes mellitus....

  14. Haemorheological factors in diabetes mellitus patients in Obafemi ...

    African Journals Online (AJOL)

    . Fifty blood samples were analyzed, comprising of thirty (30) diagnosed diabetes mellitus patients attending chemical pathology Clinic in OAUTH Ile-Ife and twenty (20) from apparently health individuals. The haemorheological parameters ...

  15. [Prevalence of fibromyalgia in diabetes mellitus and obesity].

    Science.gov (United States)

    Patucchi, Emanuele; Fatati, Giuseppe; Puxeddu, Adolfo; Coaccioli, Stefano

    2003-04-01

    To determine the prevalence of fibromyalgia in diabetes mellitus and obesity, 121 consecutive patients have been observed: 27 with obesity (6 males and 21 females; mean age 57 years, range 20-57; mean body mass index [BMI] 34); 88 with type 2 diabetes mellitus (T2DM; 40 males and 48 females; mean age 63 years, range 44-78; mean BMI 28.8; mean glycated haemoglobin [HbA1c] in the last year 8.3%); 6 with type 1 diabetes mellitus (T1DM; 2 males and 4 females; mean age 52 years, range 26-76; mean BMI 24.5; mean HbA1c BMI less that 26 the diagnosis of fibromyalgia was negative. Our data seem to reveal the presence of a significant clinical association between obesity, diabetes mellitus and fibromyalgia.

  16. Influence of diabetes mellitus on heart failure risk and outcome

    Directory of Open Access Journals (Sweden)

    Van Belle Eric

    2003-01-01

    Full Text Available Abstract Our aim is to summarize and discuss the recent literature linking diabetes mellitus with heart failure, and to address the issue of the optimal treatment for diabetic patients with heart failure. The studies linking diabetes mellitus (DM with heart failure (HF The prevalence of diabetes mellitus in heart failure populations is close to 20% compared with 4 to 6% in control populations. Epidemiological studies have demonstrated an increased risk of heart failure in diabetics; moreover, in diabetic populations, poor glycemic control has been associated with an increased risk of heart failure. Various mechanisms may link diabetes mellitus to heart failure: firstly, associated comorbidities such as hypertension may play a role; secondly, diabetes accelerates the development of coronary atherosclerosis; thirdly, experimental and clinical studies support the existence of a specific diabetic cardiomyopathy related to microangiopathy, metabolic factors or myocardial fibrosis. Subgroup analyses of randomized trials demonstrate that diabetes is also an important prognostic factor in heart failure. In addition, it has been suggested that the deleterious impact of diabetes may be especially marked in patients with ischemic cardiomyopathy. Treatment of heart failure in diabetic patients The knowledge of the diabetic status may help to define the optimal therapeutic strategy for heart failure patients. Cornerstone treatments such as ACE inhibitors or beta-blockers appear to be uniformly beneficial in diabetic and non diabetic populations. However, in ischemic cardiomyopathy, the choice of the revascularization technique may differ according to diabetic status. Finally, clinical studies are needed to determine whether improved metabolic control might favorably influence the outcome of diabetic heart failure patients.

  17. Drug-induced Liver Disease in Patients with Diabetes Mellitus

    OpenAIRE

    Iryna, Klyarytskaya; Helen, Maksymova; Elena, Stilidi

    2016-01-01

    The study presented here was accomplished to assess the course of drug-induced liver diseases in patient’s rheumatoid arthritis receiving long-term methotrexate therapy. Diabetes mellitus was revealed as the most significant risk factor. The combination of diabetes mellitus with other risk factors (female sex) resulted in increased hepatic fibrosis, degree of hepatic encephalopathy and reduction of hepatic functions. The effectiveness and safety of ursodeoxycholic acid and cytolytic type-with...

  18. A Combined Metabolomic and Proteomic Analysis of Gestational Diabetes Mellitus

    OpenAIRE

    Hajduk, Joanna; Klupczynska, Agnieszka; Dereziński, Paweł; Matysiak, Jan; Kokot, Piotr; Nowak, Dorota; Gajęcka, Marzena; Nowak-Markwitz, Ewa; Kokot, Zenon

    2015-01-01

    The aim of this pilot study was to apply a novel combined metabolomic and proteomic approach in analysis of gestational diabetes mellitus. The investigation was performed with plasma samples derived from pregnant women with diagnosed gestational diabetes mellitus (n = 18) and a matched control group (n = 13). The mass spectrometry-based analyses allowed to determine 42 free amino acids and low molecular-weight peptide profiles. Different expressions of several peptides and altered amino acid ...

  19. Sulphonylurea monotherapy for patients with type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    Hemmingsen, Bianca; Schroll, Jeppe B; Lund, Søren

    2013-01-01

    Type 2 diabetes mellitus (T2DM) is a growing health problem worldwide. Whether sulphonylureas show better, equal or worse therapeutic effects in comparison with other antidiabetic interventions for patients with T2DM remains controversial.......Type 2 diabetes mellitus (T2DM) is a growing health problem worldwide. Whether sulphonylureas show better, equal or worse therapeutic effects in comparison with other antidiabetic interventions for patients with T2DM remains controversial....

  20. Mesenchymal Stem Cell Therapy in Diabetes Mellitus: Progress and Challenges

    OpenAIRE

    El-Badri, Nagwa; Ghoneim, Mohamed A.

    2013-01-01

    Advanced type 2 diabetes mellitus is associated with significant morbidity and mortality due to cardiovascular, nervous, and renal complications. Attempts to cure diabetes mellitus using islet transplantation have been successful in providing a source for insulin secreting cells. However, limited donors, graft rejection, the need for continued immune suppression, and exhaustion of the donor cell pool prompted the search for a more sustained source of insulin secreting cells. Stem cell therapy...

  1. Study on the exchangeable body sodium in diabetes mellitus

    International Nuclear Information System (INIS)

    de Chatel, Rudolf; Barna, Istvan; Krasznai, Istvan

    1985-01-01

    Ten patients with diabetes mellitus, apperently free of any complications of diabetes and of hypertension, had a significantly (p<0.01) increased exchangeable body sodium compared to 10 sex-matched control subjects of comparable age, body weight and height, and blood pressure. Exchangeable sodium correlated significantly (p<0.01) with supine mean blood pressure in the diabetic patients (r=0.822) but not in the control subjects (r=0.276). It is suggested that the early increase of exchangeable body sodium in diabetes mellitus might play a part in the high incidence of hypertension in such patients. (author)

  2. Peripheral nervous system involvement in patients with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    P. R. Kamchatnov

    2016-01-01

    Full Text Available Diabetes mellitus is a widespread disease often affecting peripheral nervous system. This include diabetic autonomous neuropathy that can endanger the patient's life. Timely detection of complications of diabetes mellitus as well as its adequate therapy can improve prognosis of the disease. The possibilities of Milgamma and Tiogamma for pathogenic therapy in patients with diabetic polyneuropathy are considered in this paper. Gabagamma can be effectively relieve neuropathic pain and used together with other drugs that normalize nerve tissue metabolism.

  3. Serum chromium levels in gestational diabetes mellitus

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    P G Sundararaman

    2012-01-01

    Full Text Available Objective: To measure serum chromium level in women with gestational diabetes mellitus (GDM from Chennai, South India. Materials and Methods: Thirty women with gestational diabetes, 60 age matched controls. Inclusion criteria: Gestational age 22-28 weeks, age group 20-35 years. Exclusion Criteria: Gestational age beyond 28 weeks, malnutrition or presence of infection. Serum chromium was measured using inductive couple plasma emission spectrometer. Results: Serum chromium levels of women with GDM, 1.59+/-0.02 ng/ml (range: 0.16-4.0 ng/ml were lower than in controls (4.58+/-0.62 ng/ml; range 0.82-5.33 ng/ml (P < 0.001. However, there were no significant differences among cases and controls when subdivided by parity. Conclusions: Women with GDM from a South Indian city had lower levels of serum chromium compared to pregnant women without GDM. Studies may be done whether chromium supplementation is useful in this group of women.

  4. Diabetes mellitus: biosensors for research and management.

    Science.gov (United States)

    Turner, A P; Pickup, J C

    1985-01-01

    The condition of diabetes mellitus is described with particular reference to the parameters that it would be desirable to monitor in order to improve management and understanding of the disease. Previous attention has largely focused on analysis of glucose, but many other intermediates of carbohydrate, fat and protein metabolism are deranged in diabetes and may be alternative measures of control. The need for laboratory analysers, self-monitoring, closed-loop devices and alarms are detailed and the problems associated with implantable sensors discussed. Progress in the development of biosensors is reviewed using glucose sensors as the main example. Electrochemical, optoelectronic and calorimetric approaches to sensing are considered and it is concluded that configurations based either on hydrogen peroxide detection or on mediated electron transfer are most likely to provide a raid route to in vivo monitoring. The extension of biosensor technology to tackle other important substrates is discussed, the principal hurdle to success being seen as the lack of long-term stability of the biological component.

  5. SGLT2 Inhibitors in Diabetes Mellitus Treatment.

    Science.gov (United States)

    Rosas-Guzman, Juan; Rosas-Saucedo, Juan; Romero-Garcia, Alma R J

    2017-01-01

    Type 2 Diabetes Mellitus (T2DM) is a chronic illness with high prevalence in Mexico, Latin- America, and the world and is associated to high morbidity, disability, and mortality rate, especially in developing countries. T2DM physiopathology is very complex; insulin resistance in the muscle, liver, and adipose tissue, a reduction in the production of incretins (mainly GLP-1) in the intestine, increased glucagon synthesis, an insufficient response of insulin generation, and increased glucose reabsorption in the kidney lead all together to an hyperglycemic state, which has been closely associated with the development of micro and macrovascular complications. Sodium Glucose Linked Transporter 2 inhibitors (SGLT2i) are the most recent therapeutic class available for treating T2DM. SGLT2i central effect is a glycosuric action, and they can reverse the deleterious effect of tubular reabsorption of glucose in the diabetic patient resulting in greater hyperglycemia. Because their mechanism of action is completely different to current drugs, they can be considered as monotherapy or in combination with any other oral or parenteral medication, including different types of insulin or its analogues. This therapeutic synergy accomplishes a greater percentage of patients achieving glycemic control goals. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  6. Hypoglycaemia in diabetes mellitus: epidemiology and clinical implications.

    Science.gov (United States)

    Frier, Brian M

    2014-12-01

    Hypoglycaemia is a frequent adverse effect of treatment of diabetes mellitus with insulin and sulphonylureas. Fear of hypoglycaemia alters self-management of diabetes mellitus and prevents optimal glycaemic control. Mild (self-treated) and severe (requiring help) hypoglycaemia episodes are more common in type 1 diabetes mellitus but people with insulin-treated type 2 diabetes mellitus are also exposed to frequent hypoglycaemic events, many of which occur during sleep. Hypoglycaemia can disrupt many everyday activities such as driving, work performance and leisure pursuits. In addition to accidents and physical injury, the morbidity of hypoglycaemia involves the cardiovascular and central nervous systems. Whereas coma and seizures are well-recognized neurological sequelae of hypoglycaemia, much interest is currently focused on the potential for hypoglycaemia to cause dangerous and life-threatening cardiac complications, such as arrhythmias and myocardial ischaemia, and whether recurrent severe hypoglycaemia can cause permanent cognitive impairment or promote cognitive decline and accelerate the onset of dementia in middle-aged and elderly people with diabetes mellitus. Prevention of hypoglycaemia is an important part of diabetes mellitus management and strategies include patient education, glucose monitoring, appropriate adjustment of diet and medications in relation to everyday circumstances including physical exercise, and the application of new technologies such as real-time continuous glucose monitoring, modified insulin pumps and the artificial pancreas.

  7. Satisfaction of patients suffering from type 2 diabetes and/or hypertension with care offered in family medicine clinics in Mexico Satisfacción en pacientes con diabetes mellitus o hipertensión arterial atendidos en clínicas de medicina familiar en México

    Directory of Open Access Journals (Sweden)

    Svetlana Vladislavovna Doubova

    2009-06-01

    Full Text Available OBJECTIVE:To evaluate the satisfaction and the factors related to dissatisfaction in patients suffering from type 2 diabetes and/or hypertension with care offered in family medicine clinics. MATERIAL AND METHOD: A secondary data analysis was conducted. Main outcome measures were two indices of satisfaction: family doctor-patient relationship (FDPR and clinic organizational arrangements (OA. RESULTS: Approximately half of patients (n=1 323 were satisfied with care. In the FDPR index the items "kindness of the family doctor" (FD scored high, while the lowest score was for the items: "the FD allows the patient to give an opinion about his/her treatment," "the patient understands the information" and "the FD spends enough time on the consultation." As for satisfaction with OA, the items "cleanliness of the clinic" and "ease of administrative procedures" obtained the lowest scores. In the logistic regression analysis the covariate "negative self-rated health" and "type of institution" were associated with dissatisfaction. CONCLUSIONS:There are aspects of the FDPR and OA that reveal dissatisfaction of patients with chronic conditions.OBJETIVO:Analizar la satisfacción y los factores relacionados con insatisfacción en pacientes con diabetes mellitus (DM o hipertensión arterial (HTA atendidos en clínicas de medicina familiar (MF. MATERIAL Y MÉTODOS:Se realizó análisis secundario de datos. Las variables de resultado fueron dos índices de satisfacción: relación médico familiar-paciente (RMFP y aspectos organizacionales (AO. RESULTADOS:Aproximadamente la mitad de los pacientes (n=1 323 estuvieron satisfechos. Para la RMFP, "la amabilidad del MF" obtuvo la mayor calificación, y la más baja fue para "el MF permite la opinión del paciente sobre los tratamientos", "comprensión de la información" y "tiempo que el MF dedica al paciente". Para satisfacción con AO, "la limpieza de la clínica" y "fácil solución de los trámites administrativos

  8. Diagnosing gestational diabetes mellitus in the Danish National Birth Cohort.

    Science.gov (United States)

    Olsen, Sjurdur F; Houshmand-Oeregaard, Azedeh; Granström, Charlotta; Langhoff-Roos, Jens; Damm, Peter; Bech, Bodil H; Vaag, Allan A; Zhang, Cuilin

    2017-05-01

    The Danish National Birth Cohort (DNBC) contains comprehensive information on diet, lifestyle, constitutional and other major characteristics of women during pregnancy. It provides a unique source for studies on health consequences of gestational diabetes mellitus. Our aim was to identify and validate the gestational diabetes mellitus cases in the cohort. We extracted clinical information from hospital records for 1609 pregnancies included in the Danish National Birth Cohort with a diagnosis of diabetes during or before pregnancy registered in the Danish National Patient Register and/or from a Danish National Birth Cohort interview during pregnancy. We further validated the diagnosis of gestational diabetes mellitus in 2126 randomly selected pregnancies from the entire Danish National Birth Cohort. From the individual hospital records, an expert panel evaluated gestational diabetes mellitus status based on results from oral glucose tolerance tests, fasting blood glucose and Hb1c values, as well as diagnoses made by local obstetricians. The audit categorized 783 pregnancies as gestational diabetes mellitus, corresponding to 0.89% of the 87 792 pregnancies for which a pregnancy interview for self-reported diabetes in pregnancy was available. From the randomly selected group the combined information from register and interviews could correctly identify 96% (95% CI 80-99.9%) of all cases in the entire Danish National Birth Cohort population. Positive predictive value, however, was only 59% (56-61%). The combined use of data from register and interview provided a high sensitivity for gestational diabetes mellitus diagnosis. The low positive predictive value, however, suggests that systematic validation by hospital record review is essential not to underestimate the health consequences of gestational diabetes mellitus in future studies. © 2016 Nordic Federation of Societies of Obstetrics and Gynecology.

  9. Diabetes mellitus in Tropical Chronic Pancreatitis Is Not Just a Secondary Type of Diabetes

    OpenAIRE

    Rossi, L.; Parvin, S.; Hassan, Z.; Hildebrand, P.; Keller, U.; Ali, L.; Beglinger, C.; Azad Khan, A. K.; Whitcomb, David C.; Gyr, N.

    2004-01-01

    AIMS: In chronic calcific pancreatitis of the tropics, etiology and relationship to developing diabetes mellitus are unknown. Some consider these cases a straightforward secondary type of diabetes, while others suggest selective beta-cell impairment. Testing pancreatic function, we investigated whether selective beta-cell impairment triggers diabetes associated with tropical pancreatitis. METHODS: At a Bangladeshi research institute, 8 chronic tropical pancreatitis and no diabetes mellitus su...

  10. Fulminant type 1 diabetes mellitus: a case report

    Science.gov (United States)

    Yunir, E.; Nenfiati

    2018-03-01

    Type 1 diabetes mellitus is a metabolic disease caused by insulin deficiency that results from destruction of β-cells in the pancreas. Based on American Diabetes Association, there are two types of type 1 diabetes mellitus: type 1A (autoimmune) and 1B (idiopathic). In this case, we are presenting a new archetype of type 1 diabetes named fulminant type 1 diabetes mellitus. This disease results from quick destruction of β-cells byanautoimmune mechanism. The manifestation of this disease consists of unspecific flu-like symptoms, abdominal symptoms, to specific hyperglycemia symptoms such as fatigue, malaise, change in mental status that are attributable to high blood glucose and ketosis. Laboratory examination reveals high blood glucose, normal glycosylated hemoglobin, ketosis or ketoacidosis, potassium depletion and elevation of liver function tests. Treatment consists of intravenous infusion followed by insulin injection for blood glucose control, followed by treatment of metabolic derangements such as acid-base and electrolyte disorder.

  11. PREJUÍZOS COGNITIVOS EM IDOSOS COM DIABETES MELLITUS TIPO 2

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    Regina Maria Fernandes Lopes

    2009-01-01

    Full Text Available El avance en las condiciones de salud propicia el progresivo aumento de la esperanza de vida. Estudios han identificado la existencia de una conexión entre la Diabetes Mellitus (DM y demencia. La hiperglicemia podría ser un factor importante en la incidencia de la enfermedad de Azheimer, la cual puede ser una causa secundaria de demencia. La diabetes mellitus tipo 2 (DM2 está asociada con déficits cognitivos y funcionales, y el WCST es una de las herramientas que puede ser utilizada para evaluar funcionamiento ejecutivo. El objetivo de este estudio fue evaluar los déficits cognitivos de ancianos con diabetes mellitus tipo 2. Los participantes fueron 254 ancianos de ambos sexos, mayores de 60 años; 44 de ellos diagnosticados de DM2 y 210 en un grupo control de población general. El diseño fue un estudio cuantitativo transversal. Los instrumentos utilizados fueron: datos sociodemográficos, WCST, MMSE, BDI, BAI, GD, junto a las Sub pruebas de: Vocabulario, códigos, números y Cubos del WAIS-III. Los resultados mostraron una diferencia significativa en el desempeño de los ancianos con diabetes tipo 2 en comparación con el grupo control en cuatro descriptores de WCST que indicaban un deterioro. Igualmente los ancianos con diabetes tipo 2 mostraron una intensidad de síntomas depresivos y de ansiedad estadísticamente mayor que el grupo control

  12. Cuidados de Enfermería en la Diabetes Mellitus Lada

    OpenAIRE

    Gutiérrez Velicia, Soraya

    2015-01-01

    La Diabetes Mellitus es una enfermedad crónica producida por una alteración del metabolismo de la glucosa que se caracteriza por la presencia de concentraciones elevadas de glucosa en sangre, lo que se conoce como hiperglucemia. Es el trastorno endocrino crónico más prevalente. Se conocen diferentes formas de Diabetes Mellitus según su etiología: Diabetes Mellitus tipo 1, Diabetes Mellitus tipo 2, Diabetes Mellitus gestacional y otros tipos de Diabetes Mellitus como son la t...

  13. Metabolic fingerprint of Gestational Diabetes Mellitus.

    Science.gov (United States)

    Dudzik, Danuta; Zorawski, Marcin; Skotnicki, Mariusz; Zarzycki, Wieslaw; Kozlowska, Gabryela; Bibik-Malinowska, Katarzyna; Vallejo, María; García, Antonia; Barbas, Coral; Ramos, M Pilar

    2014-05-30

    Gestational Diabetes (GDM) is causing severe short- and long-term complications for mother, fetus or neonate. As yet, the metabolic alterations that are specific for the development of GDM have not been fully determined, which also precludes the early diagnosis and prognosis of this pathology. In this pilot study, we determine the metabolic fingerprint, using a multiplatform LC-QTOF/MS, GC-Q/MS and CE-TOF/MS system, of plasma and urine samples of 20 women with GDM and 20 with normal glucose tolerance in the second trimester of pregnancy. Plasma fingerprints allowed for the discrimination of GDM pregnant women from controls. In particular, lysoglycerophospholipids showed a close association with the glycemic state of the women. In addition, we identified some metabolites with a strong discriminative power, such as LPE(20:1), (20:2), (22:4); LPC(18:2), (20:4), (20:5); LPI(18:2), (20:4); LPS(20:0) and LPA(18:2), as well as taurine-bile acids and long-chain polyunsaturated fatty acid derivatives. Finally, we provide evidence for the implication of these compounds in metabolic routes, indicative of low-grade inflammation and altered redox-balance, that may be related with the specific pathophysiological context of the genesis of GDM. This highlights their potential use as prognostic markers for the identification of women at risk to develop severe glucose intolerance during pregnancy. Gestational Diabetes Mellitus (GDM) is increasing worldwide and, although diabetes usually remits after pregnancy, women with GDM have a high risk of developing postpartum type 2-diabetes, particularly when accompanied by obesity. Therefore, understanding the pathophysiology of GDM, as well as the identification of potentially modifiable risk factors and early diagnostic markers for GDM are relevant issues. In the present study, we devised a multiplatform metabolic fingerprinting approach to obtain a comprehensive picture of the early metabolic alternations that occur in GDM, and may

  14. The relative incidence of diabetes mellitus in abo/rhesus blood ...

    African Journals Online (AJOL)

    A total of 224 diabetics and 221 non-diabetics (control) were involved in this study, to determine the relative incidence of diabetes mellitus in ABO/Rhesus blood group. The current criteria for the diagnosis f diabetes mellitus were applied in differentiating the diabetics from the non-diabetics. Blood group, fasting blood sugar ...

  15. Undergraduate physiotherapy students’ knowledge of Diabetes Mellitus: Implications for education

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    T. Steyl

    2011-01-01

    Full Text Available Diabetes  mellitus  is  a  growing  public  health  concern  and its prevalence is  escalating  exponentially,  with  a  high  frequency  of morbidity, premature mortality, disability and loss of productivity.  Since health education has  become  an  important  part  of  medical  care physiotherapy  students  are potentially  well  suited  to  assist  with  the combat  of  this  disease.    The  study aimed  to  determine  the  knowledge of  diabetes  mellitus  and  its  risk  factors  of undergraduate physiotherapy students  in  the  Western  Cape.  The  study  incorporated  a  quantitative, cross-sectional design.  Three hundred and thirty eight (338 students completed the structured, self-administered questionnaire consisting of three sections, namely  socio-demographic information, diabetes mellitus risk factors and the validated 24-item diabetes Knowledge Questionnaire (dKQ-24. Both descriptive and inferential statistics were employed  and the alpha level was set at p < 0.05.  overall, 60.7% of the study sample had adequate knowledge of diabetes mellitus (≥ 75% correct answers, while 32.5% and 6.8% had marginal (≥60 ≤ 74% correct answers and inadequate knowledge (<59% correct answers respectively. Seven of the nine diabetes mellitus risk factors could readily be identified by 89.7% of the participants.  Smoking (64.8% and high blood pressure (69.0% were not readily identified as common diabetes mellitus risk factors. Significant associations with diabetes risk factors were found for gender and year of study. The study has reinforced the need for continuous education of physiotherapy students regarding diabetes mellitus and its risk factors, as inadequate knowledge of diabetes mellitus could influence the effectiveness of patient education and therefore have dangerous consequences for the patient diagnosed with diabetes mellitus.

  16. Tratamiento de la diabetes mellitus en el embarazo

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    José Manuel Rodríguez Fernández

    2014-08-01

    Full Text Available Se realizó un estudio observacional descriptivo a 929 gestantes, en el Hospital Docente Ginecobstétrico Provincial “Ana Betancourt de Mora” de la provincia de Camagüey, Cuba; en el período comprendido entre los años 2009 y 2012, con el objetivo de caracterizar el comportamiento de la diabetes en el embarazo y la terapéutica empleada en el tratamiento. El universo estuvo constituido por las embarazadas diagnosticadas con diabetes mellitus en el embarazo, las que se dividieron en dos grupos: uno con las de diagnóstico de diabetes pregestacional (127 casos y el otro con las diabéticas gestacionales (802 pacientes. Los datos se extrajeron de las historias clínicas y se procesaron según estadística descriptiva, media y desviación estándar, para cada grupo de forma independiente. Los resultados se presentaron en tablas. La media de la edad por grupos fue de 18±6 y 34±5 años, respectivamente. El número de partos por grupos fue de 0,2±1,3 para las diabéticas pregestacionales y 2±1,7 para las gestacionales; el antecedente de abortos inducidos de 0,1±0,7 en las primeras y 1±1,1 en las segundas y el de abortos espontáneos de 0,2±1,1 y 3±1,8. El tiempo de gestación al diagnóstico en las diabéticas gestacionales fue de 18±3 semanas. El tiempo de gestación al parto de 35,2±2 para el primer grupo y 40,4±0,6 semanas para el segundo y el peso del recién nacido de 2 920±212 y 3 500±232 gramos. La ganancia de peso y el peso del neonato tuvieron valores permisibles para ambos grupos. La insulina simple fraccionada a dosis menores de 30 unidades diarias fue el tratamiento más empleado. A un grupo de embarazadas se les suministró mezcla de insulina

  17. Early insulin therapy in patients with type 2 diabetes mellitus

    African Journals Online (AJOL)

    Type 2 diabetes mellitus (T2DM) is an insulin-insufficient disease characterised ... complications.1–4 Early in the onset of T2DM there is development of relative insulin ..... position statement of the American Diabetes Association (ADA) and.

  18. Risk factors for type 2 diabetes mellitus in adolescents secondary ...

    African Journals Online (AJOL)

    Background: The prevalence of Type 2 diabetes mellitus (T2 DM) in children and ... had none of the risk factors while 272(30.9%) had at least one risk factor. Using the American Diabetes Association criteria for identification of those at risk for ...

  19. Recent advances in the Management of Diabetes Mellitus | Sanusi ...

    African Journals Online (AJOL)

    Life style modi cation, oral hypoglycaemic agents, insulin therapy and islet cell transplantation are some of the approaches in the management of diabetes mellitus. Several classes of oral hypoglycemic agents like sulfonylureas, biguanides and alpha-glucosidase inhibitors are available for the treatment of type II diabetes ...

  20. Routine monitoring of diabetes mellitus in adults at primary health ...

    African Journals Online (AJOL)

    Glycaemic targets for control in type 1 diabetes mellitus* .... CGM can be useful in selected adults older than 25 years with type 1 diabetes to lower the HbA1c .... Lifestyle modifications should be addressed regularly, including weight loss if ...