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Sample records for computer-aided endoscopic sinus

  1. Endoscopic Sinus Surgery

    Science.gov (United States)

    ... sinus cavities (cancerous or non-cancerous growths), leaking brain fluid into the nose, tear duct blockage, and others. Additionally, recent advances ... bone at the bottom of the brain and brain itself that are next to the nose and sinuses have been removed via the nostril, ...

  2. Comprehensive review on endonasal endoscopic sinus surgery

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    Weber, Rainer K.; Hosemann, Werner

    2015-01-01

    Endonasal endoscopic sinus surgery is the standard procedure for surgery of most paranasal sinus diseases. Appropriate frame conditions provided, the respective procedures are safe and successful. These prerequisites encompass appropriate technical equipment, anatomical oriented surgical technique, proper patient selection, and individually adapted extent of surgery. The range of endonasal sinus operations has dramatically increased during the last 20 years and reaches from partial uncinectomy to pansinus surgery with extended surgery of the frontal (Draf type III), maxillary (grade 3–4, medial maxillectomy, prelacrimal approach) and sphenoid sinus. In addition there are operations outside and beyond the paranasal sinuses. The development of surgical technique is still constantly evolving. This article gives a comprehensive review on the most recent state of the art in endoscopic sinus surgery according to the literature with the following aspects: principles and fundamentals, surgical techniques, indications, outcome, postoperative care, nasal packing and stents, technical equipment. PMID:26770282

  3. Sinus augmentation surgery after endoscopic sinus surgery for the treatment of chronic maxillary sinusitis: a case report.

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    Tobita, Takayoshi; Nakamura, Mikiko; Ueno, Takaaki; Sano, Kazuo

    2011-10-01

    Chronic sinusitis develops when the ostiomeatal complex becomes stenosed by the swelling of the sinus mucosa. Previously, the Caldwell-Luc method was performed for the treatment of chronic sinusitis. But postoperative complications, such as discomfort of the buccal skin and recurrence of sinusitis, frequently occurred after the operation. Today, endoscopic sinus surgery (ESS) has become widely used for the treatment of chronic sinusitis. The features of ESS allow for the restoration of the physical function of the sinus membrane and preservation of the physiological environment of the sinus. Therefore, sinus augmentation surgery can be safely performed at an insufficient alveolar bone height below the maxillary sinus when sinusitis is eliminated by the ESS. This article documents a patient history involving chronic sinusitis that was treated by the ESS therapy before sinus augmentation surgery as a pretreatment for insertion of dental implants.

  4. Acute Vision Loss Following Endoscopic Sinus Surgery

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    Antisdel, Jastin

    2017-01-01

    A 41-year-old female with a history of uterine cancer and Celiac and Raynaud's Disease presented to our institution with frequent migraines and nasal congestion. She underwent functional endoscopic sinus surgery (FESS) and experienced acute unilateral vision loss postoperatively. Rapid recognition of the etiology and effective treatment are paramount given the permanent and irreversible vision loss that can result. Arterial vasospasm following FESS is rare. Patients with autoimmune diseases have perhaps an increased risk for vasospasm secondary to an increased vasoreactive profile. We present the first documented case of nitroglycerin sublingual therapy to successfully treat ophthalmic artery vasospasm following FESS. Nitroglycerin sublingual therapy is a promising treatment for ophthalmic vasospasm secondary to its ability to cross the blood-ocular barrier, its rapid onset of action, and its ability to promote relaxation of vascular smooth muscle.

  5. Acute Vision Loss Following Endoscopic Sinus Surgery

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    Serena Byrd

    2017-01-01

    Full Text Available A 41-year-old female with a history of uterine cancer and Celiac and Raynaud’s Disease presented to our institution with frequent migraines and nasal congestion. She underwent functional endoscopic sinus surgery (FESS and experienced acute unilateral vision loss postoperatively. Rapid recognition of the etiology and effective treatment are paramount given the permanent and irreversible vision loss that can result. Arterial vasospasm following FESS is rare. Patients with autoimmune diseases have perhaps an increased risk for vasospasm secondary to an increased vasoreactive profile. We present the first documented case of nitroglycerin sublingual therapy to successfully treat ophthalmic artery vasospasm following FESS. Nitroglycerin sublingual therapy is a promising treatment for ophthalmic vasospasm secondary to its ability to cross the blood-ocular barrier, its rapid onset of action, and its ability to promote relaxation of vascular smooth muscle.

  6. Image guidance in endoscopic sinus surgery and skull base surgery

    Institute of Scientific and Technical Information of China (English)

    Mitchell R.Gore; Brent A.Senior

    2012-01-01

    Objective The objective of this study was to review the current clinical applications and impact of intraoperative imaging on endoscopic sinonasal and skull base procedures in adult and pediatric patients.Methods The PubMed database was searched for articles related to the use of image guidance in otolaryngology using the search terms "image guidance otolaryngology".This was supplemented by the authors′ experience utilizing image guidance in nearly 3000 endoscopic sinus and skull base procedures.Results The literature demonstrates that intraoperative image guidance has utility in primary and revision endoscopic sinus surgery,as well as endoscopic surgery of the skull base.Image guidance also has applications in pediatric endoscopic surgery,such as pediatric sinus surgery and repair of choanal atresia.Conclusions Intraoperative image guidance,when combined with a thorough knowledge of paranasal sinus and skull base anatomy and technical proficiency,can provide improved safety when performing otolaryngologic procedures from endoscopic sinus surgery to endoscopic skull base surgery.While not a substitute for knowledge of anatomy,the increased availability and usability of image guidance systems make them a useful tool in the armamentarium of the otolaryngologist/head and neck surgeon and neurosurgeon.

  7. Role of Osteoplastic Frontal Sinus Obliteration in the Era of Endoscopic Sinus Surgery

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    Joshua B. Silverman

    2012-01-01

    Full Text Available Objective. Determining the indications for osteoplastic frontal sinus obliteration (OFSO for the treatment of inflammatory frontal sinus disease. Study Design. Retrospective case series from a single tertiary care facility. Methods. Thirty-four patients who underwent OFSO for chronic frontal sinusitis ( and frontal sinus mucocele ( comprised our study group. Data reviewed included demographics, history of prior frontal sinus operation(s, imaging, diagnosis, and operative complications. Results. The age range was 19 to 76 years. Seventy percent of patients with chronic frontal sinusitis underwent OFSO as a salvage surgery after previous frontal sinus surgery failures, while 30% underwent OFSO as a primary surgery. For those in whom OFSO was a salvage procedure, the failed surgeries were endoscopic approaches to the frontal sinus (69%, Lynch procedure (12%, and OFSO outside this study period (19%. For patients with frontal sinus mucocele, 72% had OFSO as a first-line surgery. Within the total study population, 15% of patients presented for OFSO with history of prior obliteration, with a range of 3 to 30 years between representations. Conclusions. Osteoplastic frontal sinus obliteration remains a key surgical treatment for chronic inflammatory frontal sinus disease both as a salvage procedure and first-line surgical therapy.

  8. Endoscopic transsphenoidal approach to pituitary adenomas invading the cavernous sinus

    Institute of Scientific and Technical Information of China (English)

    TAO Yu-xin; QU Qiu-yi; WANG Zhen-lin; ZHANG Qiu-hang

    2010-01-01

    Background Surgery of pituitary adenomas invading cavernous sinus has always been thought as a challenge due to the complex anatomical structures and high risk of complications. The purpose of this study was to evaluate endoscopic trarssphenoidal approach to pituitary adenomas invading cavernous sinus.Methods The clinical data of 22 patients who admitted to Xuanwu Hospital with pituitary adenomas invading cavernous sinus were analyzed retrospectively. All patients underwent endoscopic transsphenoidal surgery. To expose the surgical field sufficiently, the opening of sellar floor was exceeded the bone overlying the invaded cavernous sinus, and synthetic dura was used to repair and strengthen the sella floor for preventing the leak of cerebrospinal fluid.Results Among 22 patients, total resection was achieved in 14, subtotal resection in 5, and partial resection in 3; no patient underwent insufficient resection. Visual symptoms improved in 7 of 9 patients. In one patient diplopia disappeared.Headache was relieved to various extents in all patients. No serious complications were found. Patient's hospital stay ranged from 7 to 20 days.Conclusion These data suggest that the endoscopic transsphenoid approach is a safe, minimally invasive, and efficient surgical technique, which might be an important therapeutic strategy for the pituitary adenoms invading cavernous sinus.

  9. Combined endoscopic trephination and endoscopic frontal sinusotomy for management of complex frontal sinus pathology.

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    Batra, Pete S; Citardi, Martin J; Lanza, Donald C

    2005-01-01

    The advances in endoscopic sinus surgery have revolutionized the management of frontal sinus disease. Despite the successes, the purely endoscopic approach has its limitations, especially in patients with alterations in anatomy caused by previous surgical intervention or complex frontal sinus pneumatization patterns. The purpose of this study was to evaluate the efficacy of combined endoscopic trephination and endoscopic frontal sinusotomy (the above and below approach) in the management of these difficult cases. Chart review was performed on patients undergoing the combined approach from October 1999 to June 2004. Demographic data, symptomatology, comorbidity, previous surgery, and primary pathology were determined. Outcome was assessed based on subjective symptom relief and objective endoscopic patency. Twenty-two patients with a mean age of 49.2 years underwent the combined approach. The primary pathology included mucoceles (15 patients), frontal sinusitis (2 patients), inverted papilloma (2 patients), osteoma (1 patient), fibrous dysplasia (1 patient), and pneumocephalus (1 patient). A total of 25 above and below procedures (22 primary and 3 revision procedures) were performed to manage the pathology. Postoperatively, headaches resolved in 47%, improved in 35%, and remained unchanged in 18% of the patients. Orbital symptoms resolved in 63%, improved in 25%, and remained unchanged in 12% of the patients. Endoscopic patency of the frontal sinusotomy was confirmed in 19 of 22 cases (86%) at a mean follow-up of 16.2 months. Management of complex frontal sinus pathology may require adjunct approaches in conjunction to the standard endoscopic techniques. In this series, the above and below approach was used successfully in 22 patients. The combined approach may serve as an important adjunct for management of complex frontal sinus disease.

  10. Rhinoplasty and Functional Endoscopic Sinus Surgery

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    George L. Murrell

    2011-01-01

    Full Text Available An increasing number of patients are opting for combining sinus surgery and cosmetic rhinoplasty. The author has been performing rhinoplasty with FESS since April of 1990. The technique and equipment used in early cases is much different than that used in more recent surgeries. Specific advances include high definition monitor, intraoperative navigation system, and powered dissecting instruments. The benefits of these advances are illustrated by a review of the more recent cases performed by the author. Combined rhinoplasty and FESS can be performed with good results (functional and cosmetic and minimal complications. Advances in sinus surgery technique and equipment have made the procedure safer, faster, more precise, and more comfortable.

  11. [Unilateral frontal sinus aspergillosis: the combined endoscopic and mini-trephination approach].

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    Rinaldi, V; Portmann, D; Boudard, Ph

    2012-01-01

    Aspergillosis is a common fungal infection of the paranasal sinuses. Localization in the frontal sinus is usually secondary to involvement of one of the other sinuses. Isolated frontal sinus aspergillosis is rare and only 5 cases are described in literature. We report a case of a patient with a frontal sinus aspergilloma associated with ipsilateral chronic ethmoidal and maxillary sinusitis, successfully treated with a combined endoscopic and mini-trephination approach "Lemoyne technique". The endoscopic approach to the frontal sinus is considered the best way to deal with frontal sinus aspergilloma, but it is sometimes not sufficient to guarantee the complete removal of the fungus ball. In such cases a mini-trephination of the frontal sinus with associated irrigation provides a more accurate visualization and toilette of the sinus.

  12. Unrecognized odontogenic maxillary sinusitis: a cause of endoscopic sinus surgery failure.

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    Longhini, Anthony B; Branstetter, Barton F; Ferguson, Berrylin J

    2010-01-01

    Endoscopic sinus surgery (ESS) is reported to improve symptoms in approximately 85% of patients. Reasons for failure include misdiagnosis, technical inadequacies, underlying severe hyperplastic disease, biofilm, and immunodeficiency. Only one previous case of unrecognized odontogenic maxillary sinusitis has been cited in the literature as a reason for failure to improve with sinus surgery. This study was designed to characterize clinical and radiographic findings in patients who fail to improve with ESS because of an unrecognized dental etiology. Five patients, with odontogenic maxillary sinusitis with prior unsuccessful ESS, were prospectively enrolled. Demographics and clinical aspects including duration of illness, prior sinus surgeries and therapies, and radiographic data were assessed. Five adults underwent an average of 2.8 sinus surgeries with persistence of disease and symptoms until their dental infection was treated. Duration of symptoms ranged from 3 to 15 years. In four of five patients, the periapical abscess was not noted on the original CT report but could be seen in retrospect. Three of five patients had been seen by their dentists and told they had no dental pathology. All five patients underwent dental extractions and one patient underwent an additional ESS after dental extraction. These procedures led to a resolution of sinusitis symptoms in all five patients. Unrecognized periapical abscess is a cause of ESS failure and the radiological report frequently will fail to note the periapical infection. Dentists are unable to recognize periapical abscesses reliably with dental x-rays and exam. In patients with maxillary sinus disease, the teeth should be specifically examined as part of the radiological workup.

  13. The incidence of maxillary sinus membrane perforation during endoscopically assessed crestal sinus floor elevation: a pilot study.

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    Garbacea, Antoanela; Lozada, Jaime L; Church, Christopher A; Al-Ardah, Aladdin J; Seiberling, Kristin A; Naylor, W Patrick; Chen, Jung-Wei

    2012-08-01

    Transcrestal sinus membrane elevation is a surgical procedure performed to increase the bone volume in the maxillary sinus cavity. Because of visual limitations, the potential for maxillary sinus membrane perforations may be greater than with the lateral approach technique. The aim of this study was to macroscopically investigate ex vivo the occurrence of sinus membrane perforation during surgery using 3 transcrestal sinus floor elevation methods. Twenty fresh human cadaver heads, with 40 intact sinuses, were used for simultaneous sinus membrane elevation, placement of graft material, and dental implants. Real-time sinus endoscopy, periapical digital radiographs, and cone-beam computerized tomography (CBCT) images were subsequently used to evaluate the outcome of each surgical procedure. Perforation rates for each of the 3 techniques were then compared using a significance level of P sinus endoscope noted a higher frequency of perforations at the time of implant placement as compared with instrumentation or graft insertion, the difference was not statistically significant (P = .04). The CBCT readings were judged to be more accurate for identifying evidence of sinus perforations than the periapical radiographs when compared with the direct visualization with the endoscope. This pilot study demonstrated that a sinus membrane perforation can occur at any time during the sinus lift procedure, independent of the surgical method used.

  14. Topical Mitomycin C in functional endoscopic sinus surgery.

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    Venkatraman, Vaidyanathan; Balasubramanian, Deepak; Gopalakrishnan, Suria; Saxena, Sunil Kumar; Shanmugasundaram, Nirmal

    2012-07-01

    In recent literature, there has been an interest in the use of Mitomycin C to reduce post-operative complications following endoscopic sinus surgery. We report our results on a prospective, randomized controlled trial involving 50 patients with chronic bilateral rhino sinusitis. We eliminated various confounding factors by studying a single group of patients, with symmetrical disease, without pre-existing gross anatomical abnormalities. Patients requiring revision sinus surgery were excluded. On completion of the surgery, a cotton pledget soaked in Mitomycin C was placed in one nostril (test) and saline-soaked pledget (control) was placed in the other side of the nose, both in the middle meatus. The side of the nasal cavity receiving the topical Mitomycin C was randomized. The patients were assessed periodically (first week, first month, third month and sixth month) for synechiae formation and presence or absence of their symptoms. At the first week follow up, there was a statistically significant difference in the incidence of synechiae between the saline and Mitomycin C side. Furthermore, there was a statistically significant improvement with regards to patient symptoms (nasal block and discharge) in the Mitomycin C side when compared to the saline side. At the third and sixth month, there was no difference between the two groups. The incidence of adverse tissue reaction (granulation, discharge, polypoidal mucosa and crusting) was less in the Mitomycin C side when compared to the saline side at the first month follow up. Topically applied Mitomycin C reduces the incidence of synechiae in the immediate post-operative period in patients undergoing endoscopic sinus surgery. There is also an improvement in nasal obstruction and discharge with a reduction in the incidence of adverse tissue reaction in the early post-operative period.

  15. Olfaction in Endoscopic Sinus and Skull Base Surgery.

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    Thompson, Christopher F; Kern, Robert C; Conley, David B

    2015-10-01

    Olfactory dysfunction is a common complaint for patients with chronic rhinosinusitis, because smell loss decreases a patient's quality of life. Smell loss is caused by obstruction from polyps, nasal discharge, and mucosal edema, as well as inflammatory changes within the olfactory epithelium. Addressing olfaction before endoscopic sinus and skull base surgery is important in order to set postoperative expectations, because an improvement in smell is difficult to predict. Several commercially available olfactory testing measures are available and can easily be administered in clinic. During surgery, careful dissection within the olfactory cleft is recommended in order to optimize postoperative olfactory function.

  16. Some anatomical variation of paranasal sinuses using sinus endoscopic approach on "cadaver" in Isfahan, Iran

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    Nezamoddin Berjis

    2014-01-01

    Full Text Available Background: Due to the anatomical variations of the paranasal sinuses and its great importance in sinus surgery, as this area is in very close proximity to vital structures including the optic nerve, carotid artery, and skull base, anatomical knowledge of this area is of high importance. The purpose of this study is defining a full and clear impression of paranasal sinus anatomy and its variations as a model for the human population of the country. Materials and Methods: This study was conducted on 45 cadavers in Isfahan forensic Medicine center during 2010 to 2011. Nasal and paranasal sinuses endoscopic dissection was done with (zero and 30 o lenses (Olympus. The methods of performed dissection were via the Stamberger technique. Results: This study showed that 88.9% (40 cases of middle turbinates were in a typical form, while 6.7% (3 cases were in medial and only 4.4% (2 cases were in the lateral form. We also observed 88.9% (40 cases with Agger nasi cells, 37.8% (17 cases with Onodi cells, 28.9% cases with accessory Ostia of maxillary sinus (13 cases, and 15.6% of the cases (7 cases with concha bullosa. The position of the maxillary sinus ostium was as follows. The inferior 1/3 of hiatus semilunaris in 38 (84.5%, superior 1/3 of hiatus semilunaris in 4 (4.4%, middle 1/3 of hiatus semilunaris in 5 (11.1%. The sphenoid ostia in 53.3% (24 cases were slit shape, 28.9% (13 cases oval, and 17.8% (18 cases were round shape. Conclusion : Our survey showed that the distance between anterior nasal spine and anterior wall of the sphenoid sinus was within 7.6 ± 0.2 cm SD.

  17. Computed tomography-guided endoscopic needle knife therapy for ileal pouch sinus

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    Nyabanga, Custon T.; Veniero, Joseph; Shen, Bo

    2015-01-01

    Ileal pouch-anal anastomosis surgery can be complicated by anastomotic leaks, leading to the formation of abscess and chronic sinus that have been routinely managed by a surgical approach. We developed the endoscopic needle knife sinusotomy (NKSi) technique, which has become a valid alternative. The basic principle of endoscopic NKSi is dissection and drainage of the sinus through its orifice internally into the lumen of pouch body. The success of NKSi requires an access to the sinus from the...

  18. Healing results of prolonged acute frontal sinusitis treated with endoscopic sinus surgery.

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    Wide, Kristina; Antila, Jukka; Sipilä, Jukka; Suonpää, Jouko; Parkkola, Riitta

    2002-12-01

    In a marked part of patients suffering from acute frontal sinusitis, the symptoms do not resolve after initial therapy (antibiotics and/or trephination). The prolongation of the healing or recurrences may be caused by persistent inflammation or by structural abnormalities at the nasofrontal connection. During the last decade endoscopic surgery (FES) has become a very useful method to restore the frontonasal drainage although long term results of this kind of population are rare. We evaluated the results of endoscopic surgery in two patient groups (total number of 50) both operated after prolongation (persistent symptoms after 4 weeks) of the initial acute phase of the frontal sinusitis. The first group (A, 15 patients, first trephined) was followed-up 4 years, the number of recurrences after the first FES was 60% and in the other group (B, no initial trephination) with over 6 months follow-up, 91% of patients had recurrences. In group A pre- and postoperative CT-scanning was used to determine the possible anatomical variations that could be causing the failures. All but 3 patients showed some kind of abnormal anatomical variation. In group B only preoperative CT was done. In most cases the reasons for recurrences of frontal sinusitis were polyps and/or chronic inflammation at the ethmoidal region.

  19. Endoscopic surgery of the maxillary sinuses in oral and maxillofacial surgery practice: a literature review

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    Miroslav Andric

    2010-08-01

    Full Text Available Recently, a number of studies reported results of endoscopic surgery for treatment of odontogenic diseases of the maxillary sinuses and for sinus augmentation procedures. Therefore, the aim of this article was to review the literature data and to evaluate the level of current scientific evidence on this issue. Four retrospective and one prospective studies regarding functional endoscopic sinus surgery (FESS for odontogenic sinusitis were identified. Also, several case series of endoscope – assisted removal of odontogenic cysts and tumors involving the maxillary sinus were published. Finally, five studies regarding endoscope –controlled sinus augmentation procedures were analyzed. From available literature it seems that FESS for treatment of odontogenic sinusitis is a safe and predictable treatment option. Although scientific evidence is low, this is a clinically well documented procedure with low incidence of complications. In contrast to this, endoscopic surgery for odontogenic cysts and tumors is documented only in limited case series reports. Regarding treatment of implant – related complications, endoscopic surgery has a potential to provide effective treatment of those cases. On the other hand, endoscopic sinus augmentation needs scientific evidence of superiority to conventional techniques before it can be introduced into clinical practice.

  20. Carotid-cavernous fistula after functional endoscopic sinus surgery.

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    Karaman, Emin; Isildak, Huseyin; Haciyev, Yusuf; Kaytaz, Asim; Enver, Ozgun

    2009-03-01

    Carotid-cavernous fistulas (CCFs) are anomalous communications between the carotid arterial system and the venous cavernous sinus. They can arise because of spontaneous or trauma causes. Most caroticocavernous fistulas are of spontaneous origin and unknown etiology. Spontaneous CCF may also be associated with cavernous sinus pathology such as arteriosclerotic changes of the arterial wall, fibromuscular dysplasia, or Ehler-Danlos syndrome. Traumatic CCFs may occur after either blunt or penetrating head trauma. Their clinical presentation is related to their size and to the type of venous drainage, which can lead to a variety of symptoms, such as visual loss, proptosis, bruit, chemosis, cranial nerve impairment, intracranial hemorrhage (rare), and so on. Treatment by endovascular transarterial embolization with electrolytically detachable coils is a very effective method for CCF with good outcomes. Carotid-cavernous fistulas have been rarely reported after craniofacial surgery and are uncommon pathologies in otolaryngology practice. In this study, we report a 40-year-old woman with CCF secondary to blunt trauma of functional endoscopic sinus surgery.

  1. Clinical Features of Patients Treated with Endoscopic Sinus Surgery for Posttraumatic Paranasal Sinus Mucocele.

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    Kojima, Yusuke; Tsuzuki, Kenzo; Yukitatsu, Yoriko; Oka, Hideki; Takebayashi, Hironori; Sakagami, Masafumi

    2015-01-01

    The purpose of this study was to analyze the clinical features of patients with posttraumatic paranasal sinus mucocele (PSM). Between 2009 and 2013, we performed endoscopic sinus surgery (ESS) on 68 patients with PSM at the Department of Otolaryngology - Head and Neck Surgery at Hyogo College of Medicine. Five male patients (age range, 45-76 years) with posttraumatic PSM were analyzed retrospectively. Diagnosis was based on the history of injury and radiological findings. Posttraumatic PSM was found in 7% (5/68) of patients. The mean interval from injury to diagnosis was 28.4 years. All patients had frontal sinus mucocele. Four patients had symptoms of headache, diplopia, visual field defect, and forehead swelling, and 1 patient was asymptomatic. ESS was performed under general anesthesia in all cases, and the symptoms improved postoperatively. Reoperation was required in 1 patient (20%) because headache developed with obstruction of the frontal drainage route 7 months after ESS. Posttraumatic PSM was the least frequent form of PSM and was located predominantly in the frontal sinus, causing symptoms long after the forehead injury. The important lessons to be learned for treating posttraumatic PSM are to obtain a detailed history and to enlarge the route to the cyst to avoid its recurrence.

  2. Sphenoid mucocele; Diagnostic evaluation end endoscopic sinus surgery. Mucocele i sinus sphenoidalis; Diagnostikk og endoskopisk kirurgi

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    Elverland, H.H.; Melheim, I.; Anke, I.M.; Wideroee, E. (Regional Hospital, Tromsoe (Norway)); Rinck, P.A. (Regional Hospital, Trondheim (Norway))

    1991-02-01

    Two cases of sphenoid sinus mucocele are described. Diagnosis was based on insidious orbital symptoms, apex orbital syndrome, followed by CT and MRI examinations. In one case the mucocele was preceded by seven years of a successfully treated undifferentiated nasopharyngeal carcionma. Simple transnasal endoscopic drainage of the mucoceles gave good results, although a monocular blindness of long standing was irreversible. A high level of suspicion, combined with modern imaging techniques and prompt surgical intervention, are the prerequisites for avoiding persisting sequelae. 28 refs., 5 figs.

  3. Endoscopic endonasal repair of spontaneous sphenoid sinus lateral wall meningocele presenting with cerebrospinal fluid leak

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    Ali Erdem Yildirim

    2014-01-01

    Full Text Available Spontaneous sphenoid sinus lateral wall meningoceles are rare lesions with an unknown etiology. Endoscopic endonasal technique is a considerable route in the treatment of this condition. The aim of this paper is to report the etiology, surgical technique, and outcome in a patient repaired via endoscopic endonasal approach. A 51-year-old male patient applied with rhinorrhea started three months ago after an upper respiratory infection. There were no history of trauma or sinus operation. Biochemical analysis of the fluid was positive for beta-2-transferrin. This asypthomatic patient had undergone for repairment of lateral sphenoid sinus meningocele with endoscopic endonasal transsphenoidal approach. After endoscopic endonasal meningocele closure procedure no complications occured and a quick recovery was observed. Endoscopic endonasal approach is an effective and safe treatment modality of spontaneous lateral sphenoid sinus meningoceles and efficient in anterior skull base reconstruction.

  4. Endoscopic endonasal repair of spontaneous sphenoid sinus lateral wall meningocele presenting with cerebrospinal fluid leak.

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    Yıldırım, Ali Erdem; Dıvanlıoglu, Denizhan; Cetinalp, Nuri Eralp; Belen, Ahmed Deniz

    2014-04-01

    Spontaneous sphenoid sinus lateral wall meningoceles are rare lesions with an unknown etiology. Endoscopic endonasal technique is a considerable route in the treatment of this condition. The aim of this paper is to report the etiology, surgical technique, and outcome in a patient repaired via endoscopic endonasal approach. A 51-year-old male patient applied with rhinorrhea started three months ago after an upper respiratory infection. There were no history of trauma or sinus operation. Biochemical analysis of the fluid was positive for beta-2-transferrin. This asypthomatic patient had undergone for repairment of lateral sphenoid sinus meningocele with endoscopic endonasal transsphenoidal approach. After endoscopic endonasal meningocele closure procedure no complications occured and a quick recovery was observed. Endoscopic endonasal approach is an effective and safe treatment modality of spontaneous lateral sphenoid sinus meningoceles and efficient in anterior skull base reconstruction.

  5. ENDOSCOPIC ASSISTED APPROACH TOWARDS FRONTONASAL DERMOID CYST/CYST SINUS

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    Sharad B

    2015-07-01

    Full Text Available Nasofrontal masses belong to the group of congenital midface anomalies (CMFA in paediatric age group. The usual list of differential diagnosis for such masses can be narrowed to Frontonasal de rmoid, epidermoid, nasal encephalocele and nasal gliomas. Frontonasal dermoid with patent dermal sinus tract is a rare craniofacial anomaly resulting from the failure of normal embryonic development. Most of patients present in infancy or early childhood. CT, MRI and sinogram together are usually required for definitive diagnosis. Knowledge of embryonic development of nose & anterior skull base is important in understanding the pathologies of Frontonasal masses. Endoscopic ‘key - hole’ approach to these lesio ns via small incision allows better visualization & ensures complete removal.

  6. Role of Modified Endoscopic Medial Maxillectomy in Persistent Chronic Maxillary Sinusitis

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    Thulasidas, Ponnaiah

    2014-02-01

    Full Text Available Introduction Functional endoscopic sinus surgery has a long-term high rate of success for symptomatic improvement in patients with medically refractory chronic rhinosinusitis. As the popularity of the technique continues to grow, however, so does the population of patients with postsurgical persistent sinus disease, especially in those with a large window for ventilation and drainage. In addition, chronic infections of the sinuses especially fungal sinusitis have a higher incidence of recurrence even though a wide maxillary ostium had been performed earlier. This subset of patients often represents a challenge to the otorhinolaryngologist. Objectives To identify the patients with chronic recalcitrant maxillary sinusitis and devise treatment protocols for this subset of patients. Methods A retrospective review was done of all patients with persistent maxillary sinus disease who had undergone modified endoscopic medial maxillectomy between 2009 and 2012. We studied patient demographics, previous surgical history, and follow-up details and categorized the types of endoscopic medial maxillectomies performed in different disease situations. Results We performed modified endoscopic medial maxillectomies in 37 maxillary sinuses of 24 patients. The average age was 43.83 years. Average follow-up was 14.58 months. All patients had good disease control in postoperative visits with no clinical evidence of recurrences. Conclusion Modified endoscopic medial maxillectomy appears to be an effective surgery for treatment of chronic, recalcitrant maxillary sinusitis.

  7. Complications of vision loss and ophthalmoplegia during endoscopic sinus surgery

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    Maharshak I

    2013-03-01

    Full Text Available Idit Maharshak,1,2 Jenny K Hoang,3 M Tariq Bhatti2,4 1Department of Ophthalmology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; 2Department of Ophthalmology, 3Department of Radiology (Division of Neuroradiology, 4Department of Medicine (Division of Neurology, Duke Eye Center and Duke University Medical Center, Durham, NC, USA Objective: To describe two rare cases of concurrent vision loss and external ophthalmoplegia following powered endoscopic sinus surgery (ESS. Design: Observational case report. Results: The records of two patients who underwent powered ESS and developed multiple concurrent ophthalmic complications were retrospectively reviewed for clinical history, neuro-ophthalmologic examination, and imaging findings. Patient 1 developed a retinal vascular occlusion and complete loss of adduction. Patient 2 developed an orbital hemorrhage, optic neuropathy, and a restrictive global ophthalmoplegia. Similar published case reports were also reviewed. Conclusion: Despite advances in powered ESS technique and instrumentation, serious ophthalmic complications can still occur. Inadvertent entry into the medial orbital wall can result in a combination of blindness and ocular motility dysfunction. The variety of mechanisms responsible for these complications underscores the importance of thorough pre- and postoperative clinical examination and review of imaging studies. Keywords: sinus surgery, orbit, extra ocular muscle injury, blindness

  8. Intranasal endoscopic prelacrimal recess approach to maxillary sinus

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    ZHOU Bing; HAN De-min; CUI Shun-jiu; HUANG Qian; WANG Cheng-shuo

    2013-01-01

    Background The inferior turbinate (IT) and nasolacrimal duct (NLD) are often sacrificed while managing the diffuse lesion of maxillary sinus (MS).We report a new approach to MS without ablation of NLD and IT.Methods This retrospective study enrolled 19 hospitalized patients (aged from 42 to 68 years) who underwent endoscopic sinus surgery between 2003 and 2008.Twelve patients had inverted papilloma (IP),two had nasal polyps,two had Kubo's postoperative cyst of MS,one had recurrent bone cyst of maxilla,one had dentigerous cyst and one had bleeding of internal maxillary artery secondary to Caldwell-Luc operation respectively.Two IP patients were excluded from this group since the follow-up time was less than 12 months.The NLD was dissected after removing the anterior bony portion of nasal lateral wall.The prelacrimal recess approach (PLRA) to MS was established when IT-NLD flap was raised medially.The flap was repositioned when MS lesion was removed.Results All the 17 patients had unilateral lesions.Ten MS IP patients were at the T3 Krouse stage.The follow-up ranged from 7 to 60 months.No recurrence was seen in 16 patients.Only one IP patient had a local recurrence in MS.All of them had no any complications.Conclusion The diffuse or severe diseases of MS may be the potential indications for PLRA.

  9. Packing in endoscopic sinus surgery: is it really required?

    Science.gov (United States)

    Eliashar, Ron; Gross, Menachem; Wohlgelernter, Jay; Sichel, Jean-Yves

    2006-02-01

    The aim of this study was to evaluate the routine use of packing or local hemostatic agents in endoscopic sinus surgery (ESS). Packing and/or hemostatic agents were used only when necessary in 100 consecutive adult ESS patients in a tertiary academic hospital. Necessity for packing the nose after excessive bleeding was analyzed in relation to demographic characteristics, medical history, previous surgeries, current surgical procedure, type of anesthesia, and amount of intraoperative bleeding. Three patients who required packing because of other reasons (such as bolstering of mucosa) were excluded from the study. The remaining 97 patients included 61 males and 36 females between the ages of 16 to 86 (mean 44). Forty-nine patients underwent only ESS, 40 ESSs associated with nasal polypectomy, and 8 underwent other endoscopic procedures. Fifty-four underwent the operation under general anesthesia and 43 under local anesthesia. Intraoperative blood loss was less than 30 mL in 82 patients (85%), 30 to 50 mL in 11 (11%), and more than 50 mL in 4 (4%). In 89 patients (92%), packing or a hemostatic agent was not used. No patient had bleeding complications postoperatively. A comparison between patients who required packing to those who did not showed that the only statistically significant associations related to general anesthesia (P = 0.0082) and to the amount of intraoperative bleeding (P postoperative complications, and cost of surgery.

  10. Does amphotericin B nasal douching help prevent polyp recurrence following functional endoscopic sinus surgery?

    Directory of Open Access Journals (Sweden)

    Sayyed Mostafa Hashemi

    2011-01-01

    Conclusions: This study showed no benefits for topical amphotericin B solution over normal saline. It might be better to retreat to the traditional normal saline nasal douching following functional endoscopic sinus surgery in the treatment of polyposis.

  11. Penetration of prulifloxacin into sinus mucosa of patients undergoing paranasal sinus elective endoscopic surgery.

    Science.gov (United States)

    De Benedetto, Michele; Passali, Desiderio; Tomacelli, Giovanni; Ruggieri, Alessandro; Rosignoli, Maria Teresa; Picollo, Rossella; Bellussi, Luisa; Dionisio, Paolo

    2012-02-01

    The aim of this study was to assess the concentration of ulifloxacin, the active metabolite of prulifloxacin, in sinuses mucosa and plasma of patients with chronic rhinosinusitis, requiring sinus elective endoscopic surgery. Thirty-nine patients (30 males, 9 females; age range 22-77 years) with chronic sinusitis were enrolled, 35 were treated with the investigational medication. Samples from four untreated patients were used to validate the analytical method, while four treated patients dropped out before surgery. One 600 mg prulifloxacin tablet once daily was administered for 5 days before surgery. The last dosing was scheduled from 2 to 12 hours from tissue and plasma sampling. In each patient, two samples of paranasal sinus mucosa (from ethmoid and turbinate, respectively) and one blood sample were collected. Concentrations of ulifloxacin in plasma and sinuses mucosa were measured using validated bioanalytical LC/MS/MS methods. Individual and mean ulifloxacin concentrations in tissues were always higher than the relevant plasma levels. The highest concentrations were observed between 2.5 and 4.5 hours after the last dosing in all districts. The mean tissue/plasma ratios were 2.5 and 3.0 for ethmoid and turbinate, respectively. Data expressed as Area Under the Curves (AUC±SD) showed that ulifloxacin concentrations in the ethmoid were slightly higher (18.68±6.48 μg/g*h) than in turbinate (15.00±2.89 μg/g*h), and definitely higher than in plasma (6.32±1.14 μg/ml*h). The AUC ratios between tissues and plasma were 3.0 for ethmoides and 2.4 for turbinates. One patient reported two treatment-related episodes of diarrhea, which spontaneously resolved after the drug suspension. Results from this study seem to suggest that prulifloxacin showed good distribution in sinus tissues, where it reaches concentrations significantly higher than in plasma. These findings strongly call for confirmatory clinical trials in patients with bacterial rhinosinusitis.

  12. Endoscopic endonasal repair of spontaneous sphenoid sinus lateral wall meningocele presenting with cerebrospinal fluid leak

    OpenAIRE

    Ali Erdem Yildirim; Denizhan Divanlioglu; Nuri Eralp Cetinalp; Ahmed Deniz Belen

    2014-01-01

    Spontaneous sphenoid sinus lateral wall meningoceles are rare lesions with an unknown etiology. Endoscopic endonasal technique is a considerable route in the treatment of this condition. The aim of this paper is to report the etiology, surgical technique, and outcome in a patient repaired via endoscopic endonasal approach. A 51-year-old male patient applied with rhinorrhea started three months ago after an upper respiratory infection. There were no history of trauma or sinus operation. Bioche...

  13. Successful endoscopic management with Mitomycin C application for sinusitis with orbital cellulitis

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    Anil S Harugop

    2013-01-01

    Full Text Available Background: Sinusitis with orbital complication is a potentially fatal disease that has been known since the days of Hippocrates. Primary sinus infection is the most common cause of orbital cellulitis. It is an emergency that threatens not only vision but also life from complications such as meningitis, cavernous sinus thrombosis, and brain abscess. Surgical intervention is mandatory whenever antibiotic treatment fails. There are two surgical options for the drainage, an external approach via a Lynch incision and an intranasal endoscopic procedure. Materials and Methods: Five patients with orbital cellulitis secondary to acute on chronic rhinosinusitis were included in the study from the period of 2010 - 2011. All five patients did not respond to medical management and hence underwent endoscopic sinus surgery with treatment of orbital pathology. At the end of the surgical procedure Mitomycin C in a concentration of 0.4mg/ml was applied with a cottonoid for a period of 4 minutes to prevent chance of adhesion formation. Results: In this series 3 females and 2 male patient with orbital cellulitis secondary to acute on chronic rhinosinusitis underwent endoscopic sinus surgery with treatment of orbital pathology. All 5 patients showed subjective and objective improvement within one week of endoscopic management. Conclusion: Though antibiotics have altered the course of sinusitis, its grave complications still persist in our environment. The excellent results and the absence of any major complications of endoscopic sinus surgery and drainage of abscess with application of Mitomycin C can be recommended as the preferred surgical technique.

  14. Endoscopic- Assisted Trephination approach for repair of Frontal Sinus posterior wall fracture in a Child.

    Science.gov (United States)

    Tarrats, Luis A; Torre-León, Carlos; Almodóvar, Gustavo; Portela, Juan C

    2015-01-01

    A 9 year-old male sustained multiple maxillofacial fractures after falling from a two-store building. Frontal sinuses suffered a bilateral non-displaced linear fractures extending into the anterior and posterior walls. Magnetic resonance imaging (MRI) at this time showed a small encephalocele extending into the right frontal sinus. Operative repair was performed using an Endoscopic-Assisted Trephination approach.

  15. [Endoscopic sinus surgery for a paranasal sinuses mucocele with light guide and dacryoendoscopy].

    Science.gov (United States)

    Iwahashi, Toshihiko; Shikina, Takashi; Kawamoto, Masahiro; Mochizuki, Ryuichi; Yamashita, Maki; Inohara, Hidenori

    2013-11-01

    It is hard to cure dacryocystitis caused by a paranasal sinus mucocele with treatment which only targets the mucocele. Also, it is difficult to identify the lacrimal sac and the nasolacrimal duct preoperatively and intraoperatively when the lacrimal passage is markedly changed by the mucocele or previous surgery. We experienced four cases of mucocele complicated by lacrimal stenosis or obstruction. We performed marsupialization of the mucocele and direct silicon intubation or endoscopic dacryocystorhinostomy simultaneously with the use of a fiberoptic illuminator or dacryoendoscopy. Assisted by those devices, lacrimal procedures can now be done quickly and safely regardless of the surgeon's experience. In addition, performing surgeries both for the lacrimal passage and for the mucocele at the same time can minimize the burden on patients.

  16. The status of the middle turbinate and the risk of sinusitis after endoscopic transnasal sphenoidotomy.

    Science.gov (United States)

    Süslü, Ahmet Emre; Savaş, Özden; Özer, Serdar; Önerci, Metin

    2017-03-01

    The objectives of this study are to evaluate the occurrence of postoperative middle turbinate lateralization and the relationship between this lateralization and the risk of iatrogenic sinusitis after endoscopic transnasal sphenoidotomy procedure. Patients who undergone endoscopic transnasal sphenoidotomy and came under the surveillance of our otorhinolaryngology department between the January of 2010 and the December of 2015 were retrospectively scanned. Among them, the patients who were evaluated with paranasal sinus computed tomography (CT) postoperatively were included in the study. The amount of middle turbinate lateralization in each patient was evaluated by comparing their routine preoperative CT image with the postoperative CT image. The air-fluid levels or soft tissue opacifications in the sinuses or obstruction of the ostiomeatal complex were accepted as the evidence of sinusitis on the images. The patients were asked questions regarding their symptoms of sinusitis on a phone interview for the statistical evaluation of their preoperative and postoperative Visual Analog Scale scores of complaints of sinusitis. The difference between preoperative and postoperative measurements was found to be statistically significant (p sinus opacification and mucosal thickening rates did not change significantly which suggested the operation did not pose patients at increased risk of sinusitis. Mean VAS scores of complaints of sinusitis did not change significantly except for sensation of facial pressure, which showed a minor but statistically significant decrease (p sinusitis.

  17. Computed tomography-guided endoscopic needle knife therapy for ileal pouch sinus.

    Science.gov (United States)

    Nyabanga, Custon T; Veniero, Joseph; Shen, Bo

    2016-11-01

    Ileal pouch-anal anastomosis surgery can be complicated by anastomotic leaks, leading to the formation of abscess and chronic sinus that have been routinely managed by a surgical approach. We developed the endoscopic needle knife sinusotomy (NKSi) technique, which has become a valid alternative. The basic principle of endoscopic NKSi is dissection and drainage of the sinus through its orifice internally into the lumen of pouch body. The success of NKSi requires an access to the sinus from the pouch side. One of the most challenging situations for NKSi is a closed orifice of the sinus, which leaves an isolated chronic abscess cavity. Here we report a case of complicated presacral sinus with a closed orifice that was not amenable to NKSi, necessitating a CT-guided guide wire placement and subsequent NKSi.

  18. A new endoscopic surgical classification and invasion criteria for pituitary adenomas involving the cavernous sinus.

    Science.gov (United States)

    Ceylan, Savas; Anik, Ihsan; Koc, Kenan

    2011-01-01

    There are two major problems for the pituitary adenomas invading the Cavernous Sinus (CS); differentiation of extension and invasion and inability to demonstrate the medial wall via preoperative imaging methods. Two important corridors are defined in endoscopic cavernous sinus approaches; the lateral and medial corridor. A retrospective analysis was performed in 400 endoscopic transphenoidal approaches and 360 pituitary adenomas underwent endoscopic transphenoidal surgery in our department between September 1997 and December 2010. 48 patients affected by the tumours involving the cavernous sinus were included in this study. We performed an intraoperative evaluation of cavernous sinus invasion considering visualization of the medial wall defect, intracavernous ICA segments, minor tumour extensions through small focal pit holes of the medial wall of CS or confirming carotid segments of CS by micro-doppler. Cavernous sinus involvement was classified into three types according to the medial and lateral corridor extension of the tumor as 25 isolated medial corridor involvement (Type I), 5 isolated lateral corridor involvement (Type II) and 18 total involvement (Type III). Our classification depends on fully surgical endoscopic approach supported by neuroimaging techniques and anatomical studies and shows a good predictive value for all cavernous sinus involvement.

  19. Oral bisoprolol improves surgical field during functional endoscopic sinus surgery

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    Sumitha Mary Jacob

    2014-01-01

    Full Text Available Background: The success of functional endoscopic sinus surgery (FESS depends on visual clarity of the surgical field, through the endoscope. The objective of this double-blind, randomized, controlled study was to determine if a pre-operative dose of bisoprolol (2.5 mg would reduce the bleeding during FESS and improve the visualization of the operative field. Materials and Methods: Thirty American Society of Anesthesiologists I or II patients, scheduled for FESS were randomized to receive either a placebo (Group A or 2.5 mg of bisoprolol (Group B 90 min prior to the surgery. All the patients received standard anesthesia and monitoring. The aim was to maintain the mean arterial pressure (MAP of 60-70 mmHg, by titrating dose of isoflurane and fentanyl. The concentration of isoflurane used was recorded every 15 min. At the end of the surgery, the volume of blood loss was measured and the surgeon was asked to grade the operative field as per the Fromme-Boezaart Scale. Result: The blood loss was significantly (P < 0.0001 more in the control group (398.67 ± 228.79 ml as compared with that in the bisoprolol group (110.67 ± 45.35 ml. The surgical field was graded better in those who received bisoprolol as compared with those in the control group ( P − 0.0001. The volume percent of isoflurane and the dose of fentanyl used was significantly lower in those who received bisoprolol. During the operative period, the MAPs were 70.0 ± 2.7 (Group A and 62.6 ± 3.6 mmHg (Group B and the heart rate was 99.8 ± 5.0/min (Group A and 69.2 ± 4.4/min (Group B. These differences were statistically significant ( P − 0.001. Conclusion: This clinical trial has demonstrated that administration of a single pre-operative dose of bisoprolol (2.5 mg can significantly reduce the blood loss during FESS and improve the visualization of the operating field.

  20. Clonidine Reduce Bleeding Of Endoscopic Sinus Surgery Amir Alam Hospital (1398-2000

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    Hajy Mohammadi F

    2002-09-01

    Full Text Available This study was conducted to evaluate effect of clonidine as a premedication on endoscopic sinus surgery bleeding."nMethods and Materials: during a randomized double blind clinical trial we compared two groups of patients who scheduled for endoscopic sinus surgery for polypectomy and etmoidectomy. 216 patients randomly assigned in two groups.In first group 2 hours befor surgery a 0.2mg tablet of clonidine orally adminestered to patients and in second group a 100 mg tablet of vit Bj(with same size and color- as"nplacebowas adminestered to patients. The amount of bleeding measured in two groups."nResults: mean bleeding volume in clonidine group was 113+76 ml and in control group was 211 + 113 ml. There was a significant statistical difference between two groups (pO.0001."nConclusion: Clonidine as premedication can reduce bleeding of endoscopic sinus surgery significantly.

  1. Comparison of Clonidine and Midazolam Premedication Before Endoscopic Sinus Surgery: Results of Clinical Trial

    OpenAIRE

    Wawrzyniak, Katarzyna; Kusza, Krzysztof; Cywinski, Jacek B.

    2014-01-01

    Objectives Premedication with clonidine has been found to reduce the bleeding during endoscopic sinus surgery (ESS), therefore lowering the risk of surgical complications. Premedication is an essential part of pre-surgical care and can potentially affect magnitude of systemic stress response to a surgical procedure. The aim of this study was to compare the efficacy of premedication with clonidine and midazolam in patients undergoing sinus surgery. Methods Forty-four patients undergoing ESS fo...

  2. Endoscopic removal of an ectopic tooth in maxillary sinus.

    Science.gov (United States)

    Viterbo, Stefano; Griffa, Alessandro; Boffano, Paolo

    2013-01-01

    Ectopic teeth erupted in the maxillary sinus are rarely reported. Although the causes of eruption of a tooth into the maxillary sinus are unclear, some clinical conditions are suspected to be responsible, such as developmental disturbances (cleft palate), displacement of teeth by trauma, interventions or cyst, infection, genetic factors, crowding, and dense bone. Most cases of ectopic teeth in the maxillary sinus are asymptomatic and are occasionally diagnosed thanks to routine radiographic investigations.The aim of this article is to present and discuss the surgical management of an ectopic third molar in the roof of the maxillary sinus.

  3. Comparison between magnesium sulfate and dexmedetomidine in controlled hypotension during functional endoscopic sinus surgery

    OpenAIRE

    Adnan Bayram; Ayse Ülgey; Isin Günes; Ibrahim Ketenci; Ayse Çapar; Aliye Esmaoglu; Adem Boyaci

    2015-01-01

    BACKGROUND AND OBJECTIVES: It is crucial to decrease bleeding during functional endoscopic sinus surgery. Our primary goal was to investigate the effects of magnesium sulfate and dexmedetomidine used for controlled hypotension on the visibility of the surgical site. METHODS: 60 patients aged between 18 and 65 years were enrolled. In the magnesium sulfate ...

  4. Danger points, complications and medico-legal aspects in endoscopic sinus surgery

    Science.gov (United States)

    Hosemann, W.; Draf, C.

    2013-01-01

    Endoscopic endonasal sinus surgery represents the overall accepted type of surgical treatment for chronic rhinosinusitis. Notwithstanding raised and still evolving quality standards, surgeons performing routine endoscopic interventions are faced with minor complications in 5% and major complications in 0.5–1%. A comprehensive review on all minor and major complications of endoscopic surgery of the paranasal sinuses and also on the anterior skull base is presented listing the actual scientific literature. The pathogenesis, signs and symptoms of each complication are reviewed and therapeutic regimens are discussed in detail relating to actual publication references. Potential medico-legal aspects are explicated and recent algorithms of avoidance are mentioned taking into account options in surgical training and education. PMID:24403974

  5. Functional Endoscopic Sinus Surgery as a primary modality of treatment for primary and recurrent nasal polyposis.

    Science.gov (United States)

    Gohar, Mohammad Shahid; Niazi, Saleem Asif; Niazi, Sohail Baber

    2017-01-01

    To describe the efficacy of Functional Endoscopic Sinus Surgery(FESS) in our set up in comparison with other published studies to treat primary and recurrent nasal polyposis. This descriptive study was conducted in 02 years at Ear Nose Throat Department Combined Military Hospital (CMH) Multan from October 2013 to October 2015. Convenient sample comprising 116 patients of both sexes of age group from 18 to 60 years were selected from ENT Out Patient Department, with documented diagnosis of nasal polyposis that underwent functional endoscopic sinus surgery. Out of 116 patients, 15 (12.9%) had recurrent nasal polyposis while 101 (87.1%) had primary nasal polyposis. Patients were assessed clinically. Preoperative nasal endoscopy and CT scan of nose and paranasal sinuses were performed in every patient to assess the extent of disease and evaluate the surgical anatomy. Patients were followed up 03 monthly, 06 monthly and after 01 year. Clinical signs of nasal polyposis were evaluated by nasal endoscopy at each follow up visit. There were 116 patients with documented diagnosis of nasal polyposis. Among these, 75 (64.7%) were male and 41 (35.3%) were female patients. Mean age of presentation in males was 39.1 years and that of females was 36.7 years. Only 15 patients (12.9%) developed recurrent disease within a year. Functional endoscopic sinus surgery is preferred as a primary treatment modality for primary and recurrent nasal polyposis. Mucosal polyps can be carefully debrided, the natural ostia enlarged, the ethmoid sinuses are unroofed, and sphenoid sinuses are opened in nasal cavity and sinus nasal mucosa is mostly preserved due to excellent visualization and surgical technique. Improvement in symptoms with minimal chance of recurrence may be expected in more than 90% patients.

  6. Endoscopic sinus surgery in individuals with facial pain due to chronic maxillary sinusitis ? a functional controlled study

    Directory of Open Access Journals (Sweden)

    Giuseppe Sanges

    2014-08-01

    Full Text Available Objective: To measure the intra-sinus pressure and the maxillary sinus functional efficiency (MSFE in individuals with chronic facial pain after conservative or conventional endoscopic maxillary surgery, as well as in controls. Method: Sinus manometry was performed 5 times during inhalation. Results: The resemblance of pressure values comparing those treated with minimally invasive surgery and controls was remarkable, while traditional surgery significantly decreased intrasinusal pressures. The MSFE was 100% in the three tested times for controls, close to that in those submitted to minimally invasive surgery (98.3%, 98.8%, and 98.0% and significantly impaired after conventional surgery (48.8%, 52.1%, 48.5 %, p<0.01. All patients submitted to minimally invasive surgery remained pain-free after three months of surgery, relative to 46.7% of the submitted to conventional surgery (p<0.05. Conclusion: Minimally invasive sinus surgery is associated with functionality of the chambers that resemble what is found in normal individuals.

  7. Revison endoscopic sinus surgery for recurrent sinusitis%复发性鼻窦炎修正性鼻内镜手术

    Institute of Scientific and Technical Information of China (English)

    俞祖华; 陈剑; 张大为

    2012-01-01

    Objective To investigate the cause of recurrent sinusitis, and the security of revison endoscopic sinus surgery. Methods Revison endoscopic sinus surgery was performed to 48 patients with recurrent sinusitis. Results Of 48 patients, 32 patients were successfully cured, 11 patients showed improvement, but there was no change in other 5 patients. Conclusion Cavity adhesions, sinus ostium stenosis or atresia, residual lesions are the main reason for recurrence sinusitis. Endoscopic sinus surgery is the effective way for treatment of recurrent sinusitis.%目的 探讨复发性鼻窦炎的原因及修正性鼻内镜手术的安全性.方法 对48例复发性鼻窦炎实施修正性鼻内镜手术.结果 在治疗48例中,治愈32例;好转11例;无效5例.结论 术腔粘连、窦口狭窄闭锁、病灶残留是鼻窦炎术后复发的主要原因,修正性鼻内镜手术是治疗复发性鼻窦炎的有效方法.

  8. Entire lacrimal sac within the ethmoid sinus: outcomes of powered endoscopic dacryocystorhinostomy

    Directory of Open Access Journals (Sweden)

    Ali MJ

    2016-07-01

    Full Text Available Mohammad Javed Ali, Swati Singh, Milind N NaikInstitute of Dacryology, LV Prasad Eye Institute, Hyderabad, India Background: The aim of this study was to report the outcomes of powered endoscopic dacryocystorhinostomy (PEnDCR in patients with lacrimal sac within the sinus.Materials and methods: Retrospective analysis was performed on all patients who underwent PEnDCR and were intraoperatively documented to have complete lacrimal sac in sinus. Data collected included demographics, clinical presentations, associated lacrimal and nasal anomalies, intraoperative findings, intraoperative guidance, complications, postoperative ostium behavior, and anatomical and functional success. A minimum follow-up of 6 months postsurgery was considered for final analysis.Results: A total of 17 eyes of 15 patients underwent PEnDCR using standard protocols, but with additional intraoperative guidance where required and careful maneuvering in the ethmoid sinus. The mean age of the patients was 37.2 (range 17–60 years. Of the unilateral cases, 69% (nine of 13 showed left-side predisposition; 80% of patients showed regurgitation on pressure over the lacrimal sac area. Associated lacrimal and nasal anomalies were observed in 13.3% (two of 15 and 40% (six of 15, respectively. At a mean follow-up of 6.6 months, anatomical and functional success were observed in 93.3% (14 of 15. One patient showed failure secondary to cicatricial closure of the ostium.Conclusion: An entire sac within an ethmoid sinus poses a surgical challenge. Good sinus-surgery training, thorough knowledge of endoscopic anatomy, careful maneuvering, and use of intraoperative navigation guidance result in good outcomes with PEnDCR.Keywords: lacrimal sac, ethmoid sinus, endoscopic, DCR

  9. Endoscopic sinus surgery in chronic rhinosinusitis and nasal polyposis: a comparative study.

    Science.gov (United States)

    Nair, Satish; Dutta, Angshuman; Rajagopalan, Ramakrishnan; Nambiar, Sapna

    2011-01-01

    Nasal polyposis are common presentations in patients of chronic rhinosinusitis and are considered to be associated with more severe forms of disease with poor treatment outcome. The presentation and treatment outcome after endoscopic sinus surgery in patients of chronic rhinosinusitis and nasal polyposis have been analysed in this study. A prospective analysis of 90 patients of chronic rhinosinusitis who were classified into two groups depending on presence and absence of nasal polyps was performed in the study. The two groups were evaluated using subjective (patient complaints) and objective (computed tomography scan and endoscopy scores) criteria. Preoperative data were compared with data obtained 12 months post endoscopic sinus surgery. The study included 38 patients of chronic rhinosinusitis and 52 patients of nasal polyps. The patients of nasal polyp group presented with increased severity of symptoms of nasal blockage, nasal discharge and reduced sense of smell as compared to the chronic rhinosinusitis group who had significantly higher presentation of headache and facial pain. The preoperative CT scan revealed significantly higher bilateral disease with increased involvement of multiple sinuses in nasal polyp group. Post endoscopic sinus surgery both the groups showed significant improvement in their symptoms with the nasal polyp group demonstrating reduction in improvement on 1 year follow up. In our study we have found the patients with chronic rhinosinusitis and nasal polyp have varied severity of symptoms with the nasal polyp group having higher nasal symptoms and increased severity as compared to chronic rhinosinusitis group. Though the universal rationale of management by adequate drainage and ventilation of sinus is similar in both groups, there is a reduction in both objective and subjective scores during 1 year follow up in the nasal polyp group.

  10. A Novel Augmented Reality Navigation System for Endoscopic Sinus and Skull Base Surgery: A Feasibility Study.

    Science.gov (United States)

    Li, Liang; Yang, Jian; Chu, Yakui; Wu, Wenbo; Xue, Jin; Liang, Ping; Chen, Lei

    2016-01-01

    To verify the reliability and clinical feasibility of a self-developed navigation system based on an augmented reality technique for endoscopic sinus and skull base surgery. In this study we performed a head phantom and cadaver experiment to determine the display effect and accuracy of our navigational system. We compared cadaver head-based simulated operations, the target registration error, operation time, and National Aeronautics and Space Administration Task Load Index scores of our navigation system to conventional navigation systems. The navigation system developed in this study has a novel display mode capable of fusing endoscopic images to three-dimensional (3-D) virtual images. In the cadaver head experiment, the target registration error was 1.28 ± 0.45 mm, which met the accepted standards of a navigation system used for nasal endoscopic surgery. Compared with conventional navigation systems, the new system was more effective in terms of operation time and the mental workload of surgeons, which is especially important for less experienced surgeons. The self-developed augmented reality navigation system for endoscopic sinus and skull base surgery appears to have advantages that outweigh those of conventional navigation systems. We conclude that this navigational system will provide rhinologists with more intuitive and more detailed imaging information, thus reducing the judgment time and mental workload of surgeons when performing complex sinus and skull base surgeries. Ultimately, this new navigational system has potential to increase the quality of surgeries. In addition, the augmented reality navigational system could be of interest to junior doctors being trained in endoscopic techniques because it could speed up their learning. However, it should be noted that the navigation system serves as an adjunct to a surgeon's skills and knowledge, not as a substitute.

  11. A Novel Augmented Reality Navigation System for Endoscopic Sinus and Skull Base Surgery: A Feasibility Study

    Science.gov (United States)

    Li, Liang; Yang, Jian; Chu, Yakui; Wu, Wenbo; Xue, Jin; Liang, Ping; Chen, Lei

    2016-01-01

    Objective To verify the reliability and clinical feasibility of a self-developed navigation system based on an augmented reality technique for endoscopic sinus and skull base surgery. Materials and Methods In this study we performed a head phantom and cadaver experiment to determine the display effect and accuracy of our navigational system. We compared cadaver head-based simulated operations, the target registration error, operation time, and National Aeronautics and Space Administration Task Load Index scores of our navigation system to conventional navigation systems. Results The navigation system developed in this study has a novel display mode capable of fusing endoscopic images to three-dimensional (3-D) virtual images. In the cadaver head experiment, the target registration error was 1.28 ± 0.45 mm, which met the accepted standards of a navigation system used for nasal endoscopic surgery. Compared with conventional navigation systems, the new system was more effective in terms of operation time and the mental workload of surgeons, which is especially important for less experienced surgeons. Conclusion The self-developed augmented reality navigation system for endoscopic sinus and skull base surgery appears to have advantages that outweigh those of conventional navigation systems. We conclude that this navigational system will provide rhinologists with more intuitive and more detailed imaging information, thus reducing the judgment time and mental workload of surgeons when performing complex sinus and skull base surgeries. Ultimately, this new navigational system has potential to increase the quality of surgeries. In addition, the augmented reality navigational system could be of interest to junior doctors being trained in endoscopic techniques because it could speed up their learning. However, it should be noted that the navigation system serves as an adjunct to a surgeon’s skills and knowledge, not as a substitute. PMID:26757365

  12. A Novel Augmented Reality Navigation System for Endoscopic Sinus and Skull Base Surgery: A Feasibility Study.

    Directory of Open Access Journals (Sweden)

    Liang Li

    Full Text Available To verify the reliability and clinical feasibility of a self-developed navigation system based on an augmented reality technique for endoscopic sinus and skull base surgery.In this study we performed a head phantom and cadaver experiment to determine the display effect and accuracy of our navigational system. We compared cadaver head-based simulated operations, the target registration error, operation time, and National Aeronautics and Space Administration Task Load Index scores of our navigation system to conventional navigation systems.The navigation system developed in this study has a novel display mode capable of fusing endoscopic images to three-dimensional (3-D virtual images. In the cadaver head experiment, the target registration error was 1.28 ± 0.45 mm, which met the accepted standards of a navigation system used for nasal endoscopic surgery. Compared with conventional navigation systems, the new system was more effective in terms of operation time and the mental workload of surgeons, which is especially important for less experienced surgeons.The self-developed augmented reality navigation system for endoscopic sinus and skull base surgery appears to have advantages that outweigh those of conventional navigation systems. We conclude that this navigational system will provide rhinologists with more intuitive and more detailed imaging information, thus reducing the judgment time and mental workload of surgeons when performing complex sinus and skull base surgeries. Ultimately, this new navigational system has potential to increase the quality of surgeries. In addition, the augmented reality navigational system could be of interest to junior doctors being trained in endoscopic techniques because it could speed up their learning. However, it should be noted that the navigation system serves as an adjunct to a surgeon's skills and knowledge, not as a substitute.

  13. Transnasal, Endoscopically Guided Skull-Based Surgery by Pharyngotomy for Mass Removal from the Sphenopalatine Sinus in a Horse.

    Science.gov (United States)

    Radcliffe, Rolfe M; Messiaen, Yasmine; Irby, Nita L; Divers, Thomas J; Dewey, Curtis W; Mitchell, Katharyn J; Schnabel, Lauren V; Bezuidenhout, Abraham J; Scrivani, Peter V; Ducharme, Norm G

    2016-11-01

    To report a transnasal, endoscopically guided ventral surgical approach for accessing the cranial and caudal segments of the sphenopalatine sinus for mass removal in a horse. Case report. Adult horse with acute onset blindness referable to a soft tissue mass within the sphenopalatine sinus. A 7-year-old Warmblood gelding presented with a history of running into a fence and falling. No neurologic signs were identified at initial examination but acute blindness was noted 3 weeks later. On computed tomography (CT) the sphenopalatine sinus was filled with a large homogeneous mass with poor contrast enhancement that extended dorsally with thinning to the dorsal cortex of the sphenoid bone, just rostral to the entrance of the optic canals into the cranial cavity. Surgical access to the sphenopalatine sinus was achieved using a transnasal, endoscopically guided ventral pharyngotomy approach and the mass lesion was removed. A presumptive diagnosis of chondroma was made based on histopathology. The horse recovered well from surgery, and although it has not regained vision as of 6.5 years postoperatively, the disease has not progressed. Transnasal, endoscopically-guided ventral surgical access to the sphenopalatine sinus is possible in horses and may improve access in horses with disease extending caudally beyond the palatine portion of the sinus. Use of smaller diameter or specialized instruments, such as various endoscopic bone cutting instruments, and CT image guidance may improve sinus access by this route. © Copyright 2016 by The American College of Veterinary Surgeons.

  14. Sinusitis

    Science.gov (United States)

    Sinusitis means your sinuses are inflamed. The cause can be an infection or another problem. Your sinuses ... and cause pain. There are several types of sinusitis, including Acute, which lasts up to 4 weeks ...

  15. Computer-aided recording of automatic endoscope washing and disinfection processes as an integral part of medical documentation for quality assurance purposes

    Directory of Open Access Journals (Sweden)

    Klein Stefanie

    2010-07-01

    Full Text Available Abstract Background The reprocessing of medical endoscopes is carried out using automatic cleaning and disinfection machines. The documentation and archiving of records of properly conducted reprocessing procedures is the last and increasingly important part of the reprocessing cycle for flexible endoscopes. Methods This report describes a new computer program designed to monitor and document the automatic reprocessing of flexible endoscopes and accessories in fully automatic washer-disinfectors; it does not contain nor compensate the manual cleaning step. The program implements national standards for the monitoring of hygiene in flexible endoscopes and the guidelines for the reprocessing of medical products. No FDA approval has been obtained up to now. The advantages of this newly developed computer program are firstly that it simplifies the documentation procedures of medical endoscopes and that it could be used universally with any washer-disinfector and that it is independent of the various interfaces and software products provided by the individual suppliers of washer-disinfectors. Results The computer program presented here has been tested on a total of four washer-disinfectors in more than 6000 medical examinations within 9 months. Conclusions We present for the first time an electronic documentation system for automated washer-disinfectors for medical devices e.g. flexible endoscopes which can be used on any washer-disinfectors that documents the procedures involved in the automatic cleaning process and can be easily connected to most hospital documentation systems.

  16. Transnasal endoscopic treatment of orbital complications of acute sinusitis: the Graz concept.

    Science.gov (United States)

    Teinzer, Fabian; Stammberger, Heinz; Tomazic, Peter Valentin

    2015-05-01

    Orbital complications of acute sinusitis can be severe. Nowadays, surgical drainage of intraorbital abscess formations is performed endoscopically in the majority of cases. This study aims to illustrate the Graz experience in the endoscopic treatment of orbital complications and to present our treatment algorithm. In a retrospective study, 53 patients were examined who were referred to the Department of General Otorhinolaryngology of the ENT-University Hospital Graz from 2000 to 2011. Of 53 patients, men were affected more frequently than women (n=37, 69.81% vs n=16, 30.19%). The following diagnoses were obtained: 9 preseptal cellulitis, 7 orbital cellulitis, 14 subperiosteal abscesses, and 23 orbital abscesses. In 16 patients, a conservative therapy was administered; 37 patients underwent surgery, most of them purely endoscopically (n=31, 83.78%). Two of the patients who underwent conservative treatment and 7 of those who underwent surgery experienced a recurrence (n=9, 16.98%). Based on analysis of our recurrences, we have tried to create the optimal treatment algorithm as a point of reference in the management of orbital complications of acute sinusitis. In this way, 7 of 9 recurrences could have been avoided, equaling a hypothetical recurrence rate of 3.77% instead of 16.98% (hypothetical success rate 96.23%). © The Author(s) 2014.

  17. Orbital apex cyst: a rare cause of compressive optic neuropathy post-functional endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    Koh YN

    2017-07-01

    Full Text Available Yi Ni Koh,1,2 Shu Fen Ho,2 Letchumanan Pathma,3 Harvinder Singh,3 Embong Zunaina1 1Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Department of Ophthalmology, 3Department of Otorhinolaryngology, Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia Abstract: There are various causes that can lead to compressive optic neuropathy. We present here orbital apex cyst as an unusual cause of compressive optic neuropathy in a 49-year-old male. He presented with 2 weeks painless loss of vision in the left eye with left-sided headache. He had had left functional endoscopic sinus surgery for left nasal polyps 4 years earlier. Magnetic resonance imaging of brain and orbit revealed a left discrete orbital nodule, possibly orbital cyst or mucocele, which was compressing on the left optic nerve. Left eye vision improved markedly from hand movement to 6/36 pinhole 6/18 after initiation of intravenous dexamethasone. A subsequent endoscopic endonasal left optic nerve decompression found the orbital nodule lesion to be an orbital cyst. Marsupialization was performed instead of excision, as the cyst ruptured intraoperatively. Postoperative vision improved to 6/7.5 with normal optic nerve function postoperatively. Possible cause of orbital apex cyst is discussed. Keywords: orbital cyst, compressive optic neuropathy, functional endoscopic sinus surgery

  18. Treatment of paranasal sinuses mycosis with endoscopic sinus surgery%鼻内镜手术治疗非侵袭性鼻窦真菌病

    Institute of Scientific and Technical Information of China (English)

    朱其新; 陈敏玲; 何植洲

    2009-01-01

    Objective To evaluate the treatment effect of endoscopic sinus surgery on the paranasal sinuses mycosis. Methods Twenty-one cases with nasal sinus mycoses were analyzed retrospectively .All of them had undergone endoscopic operation.Results In the follow up of 6~24 months, all cases were cured. Conclusion Endoscopic operation is the basic surgical method to treat the non-invasive nasal sinus mycoses. Excising the focus thoroughly, correcting the abnormal nasal cavity structure and resuming the cleanout function of nasal sinus cilia are the principle of treatment.%目的 探讨鼻内镜手术代替传统柯-陆手术治疗非侵袭性鼻窦真菌病的疗效.方法 总结分析我科近5年来采用鼻内镜手术治疗21例非侵袭性鼻窦真菌病患者.结果 21例患者术后随访6~24个月,原有症状消失,未见复发.结论 鼻内镜为治疗本病基本术式,彻底清除病灶、纠正鼻腔结构异常及恢复鼻窦纤毛功能为治疗原则.

  19. Sinusitis

    OpenAIRE

    Gómez, Luz Eugenia; Fundación Valle de Lili

    2000-01-01

    ¿Qué son los senos para nasales?/ ¿Qué es la sinusitis?/Tipos de sinusitis/Causas de sinusitis/Factores que predisponen/La sinusitis y su relación con otras enfermedades del tracto respiratorio/Signos y síntomas/Complicaciones de la sinusitis.

  20. Sinusitis

    OpenAIRE

    2000-01-01

    ¿Qué son los senos para nasales?/ ¿Qué es la sinusitis?/Tipos de sinusitis/Causas de sinusitis/Factores que predisponen/La sinusitis y su relación con otras enfermedades del tracto respiratorio/Signos y síntomas/Complicaciones de la sinusitis.

  1. Computer aided control engineering

    DEFF Research Database (Denmark)

    Szymkat, Maciej; Ravn, Ole

    1997-01-01

    Current developments in the field of Computer Aided Control Engineering (CACE) have a visible impact on the design methodologies and the structure of the software tools supporting them. Today control engineers has at their disposal libraries, packages or programming environments that may be speci......Current developments in the field of Computer Aided Control Engineering (CACE) have a visible impact on the design methodologies and the structure of the software tools supporting them. Today control engineers has at their disposal libraries, packages or programming environments that may...

  2. Anatomia endoscópica do seio esfenoidal Endoscopic anatomy of the sphenoid sinus

    Directory of Open Access Journals (Sweden)

    Alexandre A. Murta

    2002-08-01

    Full Text Available Introdução: A importância da compreensão da anatomia interna do seio esfenoidal deve-se à sua peculiar localização no centro do crânio, com estruturas vizinhas de nobreza indiscutível, e por transparecer estas relações anatômicas em suas delgadas paredes internas. Forma de estudo: Anatômico. Material e método: No presente estudo foram dissecados endoscopicamente 52 seios esfenoidais, sendo suas saliências e depressões internas analisadas, correspondentes aos relevos internos produzidos pela artéria carótida interna, nervo óptico, nervo maxilar, e nervo vidiano. Resultado: Em 88,5% dos casos a artéria carótida interna apresentou-se saliente, e o nervo óptico o fez em 55,8%. O nervo vidiano e o nervo maxilar mostraram-se visíveis em 25% e 30,8% dos casos, respectivamente. Conclusão: Tais dados nos chamam a atenção para a rica e frágil anatomia interna do seio esfenoidal que, devido ao avanço dos métodos de cirurgia endoscópica, está progressivamente mais próxima e vulnerável a manobras e procedimentos cirúrgicos. Assim, sua compreensão torna-se essencial quando se trata de cirurgia endoscópica endonasal e seu horizonte de recursos técnicos.Introduction: The internal anatomy of the sphenoid sinus plays a role of great importance due to its peculiar placement in the center of the head, surrounded by important adjacent structures, which make themselves transparent in its internal walls. Study design: Anatomic. Material and method: In this study, 52 sphenoid sinus were endoscopically dissected, and the elevations and depressions presented on its internal walls, produced by the internal carotid artery and the optic, maxillary and vidian nerves, were analyzed. Results: In 88,5% of the cases, the internal carotid artery were projected into the sinus, while the optic nerve were in 55,8%. The vidian and maxillary nerves were salient in 25% and 30% respectively. Conclusion: These data point us to the rich end delicate

  3. Sinusitis

    National Research Council Canada - National Science Library

    Morcom, Samuel; Phillips, Nicholas; Pastuszek, Andrew; Timperley, Daniel

    2016-01-01

    Background: Acute and chronic sinusitis are common primary care presentations. They are caused by mucosal inflammation, which inhibits mucociliary function of the nose and paranasal sinuses. Objective...

  4. Computer Aided Lecturing.

    Science.gov (United States)

    Van Meter, Donald E.

    1994-01-01

    Surveyed students taking a natural resource conservation course to determine the effects of computer software that provides tools for creating and managing visual presentations to students. Results indicated that 94% of the respondents believed computer-aided lectures helped them and recommended their continued use; note taking was more effective,…

  5. Spontaneous sphenoid wing meningoencephaloceles with lateral sphenoid sinus extension: the endoscopic transpterygoid approach.

    Science.gov (United States)

    Ajlan, Abdulrazag; Achrol, Achal; Soudry, Ethan; Hwang, Peter H; Harsh, Griffith

    2014-10-01

    Spontaneous meningoencephalocele (SME) of the sphenoid wing is a rare cause of cerebrospinal fluid (CSF) leakage. Surgical closure of the fistula is usually required. The approach taken depends on the location of the defect and the extension of the meningoencephalocele. The endoscopic transpterygoid approach may be useful. We prospectively analyzed the three cases of SME of the sphenoid wing with lateral sphenoid sinus extension treated endoscopically at Stanford over the last 3 years with regard to imaging findings, operative technique, and operative morbidity. In our three cases, the extent of pterygopalatine fossa (PPF) exposure undertaken, complete in one and partial in two, depended on the defect site. Follow-up ranged from 17 to 25 months. The fistula was completely closed in all three cases. Extant literature reports a 97% rate of successful closure (N = 65 of 67, with a mean follow-up of 25 months) and no major complications. Endoscopic transpterygoid repair is a useful, safe alternative to traditional approaches for repair of SME of the sphenoid wing. Its feasibility depends on the site of the defect, which can be identified by preoperative imaging. Larger PPF exposure and postoperative lumbar drainage of CSF can be useful and have a low risk of morbidity.

  6. Computer aided product design

    DEFF Research Database (Denmark)

    Constantinou, Leonidas; Bagherpour, Khosrow; Gani, Rafiqul

    1996-01-01

    A general methodology for Computer Aided Product Design (CAPD) with specified property constraints which is capable of solving a large range of problems is presented. The methodology employs the group contribution approach, generates acyclic, cyclic and aromatic compounds of various degrees......-liquid equilibria (LLE), solid-liquid equilibria (SLE) and gas solubility. Finally, a computer program based on the extended methodology has been developed and the results from five case studies highlighting various features of the methodology are presented....

  7. Patient satisfaction and treatment outcome of fungus ball rhinosinusitis treated by functional endoscopic sinus surgery.

    Science.gov (United States)

    Lai, Jui-Chung; Lee, Hong-Shen; Chen, Mu-Kuan; Tsai, Yao-Lung

    2011-02-01

    Fungal rhinosinusitis is an important clinical problem with diverse manifestations. Although many literatures had found low recurrence rate after surgical treatment of fungus ball rhinosinusitis, patient satisfaction and treatment outcomes (symptom-free and symptom improvement rate, etc.) for fungus ball sinusitis are not yet well established. The purpose of this study is to estimate the patient satisfaction and treatment outcome in patients with fungus ball rhinosinusitis undergoing functional endoscopic sinus surgery (FESS). Medical records of consecutive patients with diagnosed fungus ball rhinosinusitis treated by FESS between 1995 and 2005 were reviewed retrospectively. The post-operative improvement in individual symptom was assessed by chart review and telephone visiting. Ninety consecutive patients (21 men and 69 women) were eligible for the study. Six patients (7%) presented bilateral fungus ball rhinosinusitis. Multiple paranasal sinus fungus ball involvements were found in 48 patients (53%). Complete resolution of complaints with respect to nasal discharge, postnasal drip, cough with sputum, nasal bleeding, fetid odor of nose, olfactory dysfunction, nasal obstruction, headache, and facial pain or pressure were described in 74 patients (82%). The overall patient satisfaction rate was 96%. The estimated recurrence rate of fungus ball rhinosinusitis treated with FESS was 3%, with a mean follow-up of 81 months. Treatment protocol of fungus ball rhinosinusitis with FESS and without postoperative antifungal drugs is efficient because of very low recurrence rate, high patient satisfaction, and very high symptom-free rate. Furthermore, the obvious difference of symptom-free rate between fungus ball rhinosinusitis and chronic rhinosinusitis highlights the need of further studies to discover the pathophysiology of fungal sinusitis.

  8. Computer aided drug design

    Science.gov (United States)

    Jain, A.

    2017-08-01

    Computer based method can help in discovery of leads and can potentially eliminate chemical synthesis and screening of many irrelevant compounds, and in this way, it save time as well as cost. Molecular modeling systems are powerful tools for building, visualizing, analyzing and storing models of complex molecular structure that can help to interpretate structure activity relationship. The use of various techniques of molecular mechanics and dynamics and software in Computer aided drug design along with statistics analysis is powerful tool for the medicinal chemistry to synthesis therapeutic and effective drugs with minimum side effect.

  9. Computer aided control engineering

    DEFF Research Database (Denmark)

    Szymkat, Maciej; Ravn, Ole

    1997-01-01

    levels.The major conclusions of the paper are related with identifying the factors affecting the software tool integration in a way needed to facilitate design "inter-phase" communication. These are: standard application interfaces, dynamic data exchange mechanisms, code generation techniques and general......Current developments in the field of Computer Aided Control Engineering (CACE) have a visible impact on the design methodologies and the structure of the software tools supporting them. Today control engineers has at their disposal libraries, packages or programming environments that may...

  10. Radiological findings in patients undergoing revision endoscopic sinus surgery: a retrospective case series study

    Directory of Open Access Journals (Sweden)

    Eweiss Ahmed Z

    2011-05-01

    Full Text Available Abstract Background Functional endoscopic sinus surgery (FESS is now a well-established strategy for the treatment of chronic rhinosinusitis which has not responded to medical treatment. There is a wide variation in the practice of FESS by various surgeons within the UK and in other countries. Objectives To identify anatomic factors that may predispose to persistent or recurrent disease in patients undergoing revision FESS. Methods Retrospective review of axial and coronal CT scans of patients undergoing revision FESS between January 2005 and November 2008 in a tertiary referral centre in South West of England. Results The CT scans of 63 patients undergoing revision FESS were reviewed. Among the patients studied, 15.9% had significant deviation of the nasal septum. Lateralised middle turbinates were present in 11.1% of the studied sides, and residual uncinate processes were identified in 57.1% of the studied sides. There were residual cells in the frontal recess in 96% of the studied sides. There were persistent other anterior and posterior ethmoidal cells in 92.1% and 96% of the studied sides respectively. Conclusions Analysis of CT scans of patients undergoing revision FESS shows persistent structures and non-dissected cells that may be responsible for persistence or recurrence of rhinosinusitis symptoms. Trials comparing the outcome of conservative FESS techniques with more radical sinus dissections are required.

  11. A RETROSPECTIVE STUDY OF THE IMPACT OF MEAN ARTERIAL PRESSURE ON ESTIMATED BLOOD LOSS DURING ENDOSCOPIC SINUS SURGERY

    Directory of Open Access Journals (Sweden)

    George W Williams

    2014-10-01

    Full Text Available The current practice of lowering mean arterial pressure (MAP during endoscopic sinus surgery (ESS is common, but unproven with regard to peer reviewed literature. The controlled hypotension induced is aimed for improved surgical field and lower the blood loss. Lower mean arterial pressures especially for prolonged surgeries may result in end organ hypoperfusion. The authors reviewed all patients who underwent outpatient endoscopic sinus surgery for the diagnosis of chronic sinusitis from January 1, 2012 to December 31, 2012 at Memorial Hermann Hospital – Texas Medical Centre. We individually reviewed case sheets of every patient and documented blood loss as recorded on the anaesthesia record or in the surgical procedure note, among other variables. A total of 326 patients were included in this study. The median estimated blood loss (EBL was found to be 50 ml. The multivariate regression analysis between these three groups showed that EBL was higher in MAP 75 group. The average of EBL in MAP75 group and the average of EBL in MAP 65-70 group is 42% higher than that in MAP>75 group when other variables were fixed. Hence we found the trend toward higher blood loss with lower MAP. The authors conclude that lower MAP does not result in lower EBL in endoscopic sinus surgery. Furthermore, increases in BMI and crystalloid administered during an aesthetic management of these cases correlates with increased estimate blood loss.

  12. Anatomic findings in revision endoscopic sinus surgery: Case series and review of contributory factors

    Science.gov (United States)

    Bewick, Jessica; Egro, Francesco M.; Masterson, Liam; Javer, Amin R.

    2016-01-01

    Background: It is recognized that patients who undergo endoscopic sinus surgery (ESS) do not always achieve control of their disease. The causes are multifactorial; variations in surgical practice have been identified as possible factors in refractory disease. Objective: To reflect on the frequent anatomic findings of patients with chronic rhinosinusitis (CRS) who require revision ESS. Methods: A retrospective review of patients who required revision ESS at a tertiary institution over a 3-year period. Patients for whom maximal medical therapy failed for CRS underwent computed tomography of the paranasal sinuses and image-guided surgery. Surgical records of anatomic findings were reviewed and analyzed. Results: Over 3 years, a total of 75 patients underwent revision procedures, 28% of all ESS performed in the unit. The most frequent finding was a residual uncinate process in 64% of the patients (n = 48); other findings included a maxillary antrostomy not based on the natural ostium of the maxillary sinus in 47% (n = 35), an oversized antrostomy in 29% (n = 22), resected middle turbinates in 35% (n = 26), middle meatal stenosis in 15% (n = 11), synechiae in 29% (n = 22), and osteitic bone that required drilling in 13% (n = 10). Conclusion: Surgical technique can give rise to anatomic variations that may prevent adequate mucociliary clearance and medication delivery, which leads to failure in ESS in patients with CRS. This study demonstrated the surgical findings encountered in revision ESS that should be highlighted in the training of Ear, Nose and Throat surgeons to help prevent primary failure and reduce health care costs. PMID:28107148

  13. Prevention of Adhesion after Endoscopic Sinus Surgery: Role of Mitomycin C

    Directory of Open Access Journals (Sweden)

    Mohammad-Hossein Baradaranfar

    2011-03-01

    Full Text Available Adhesions after endoscopic sinus surgery (ESS are a potential cause of surgical failure. Mitomycin-C (MMC is recently proposed as a solution for these adhesions. This study was performed to investigate the effect of Mitomycin C in reducing scar formation and adhesion in the nasal mucosa after endoscopic nasal surgery. This double blind randomized clinical trial study was performed on 37 patients with bilateral chronic rhinosinusitis. At the end of ESS, randomly impregnated mesh with MMC was placed in one side and another mesh impregnated with saline in the opposite side for 5 minutes. Patients were followed at least for three months, and the results of diagnostic endoscopy were recorded. Post operative adhesion occurred in 12 (32.4% patients (2 bilateral/10 unilateral. Among total of 14 adhesions, 4 (10.8% were in the MMC side and 10 (27% in the control side. This differences was close to statistically significant (P=0.058. MMC may reduce adhesions after ESS, but further studies with different doses, sample size and frequent use of topical MMC is recommended.

  14. Evaluation of resident's training for endoscopic sinus surgery using a sheep's head.

    Science.gov (United States)

    Delgado-Vargas, Beatriz; Romero-Salazar, Azucena Lloris; Reyes Burneo, Pablo M; Vásquez Hincapie, Catalina; de Los Santos Granado, Gonzalo; Del Castillo López, Raúl; Frágola Arnau, Claudio; Cobeta Marco, Ignacio

    2016-08-01

    Training in functional endoscopic sinus surgery (FESS) is an essential part of each ENT resident and it takes place on a very fragile area. This study focus on showing the learning curve of FESS, using an anatomical model such as the sheep's head. Four residents in our centre performed dissections. Each of these residents operated eight sheep's head. They performed an endoscopic septoplasty followed by maxillary antrostomy, total ethmoidectomy and frontal sinusotomy on every head. A staff member guided all procedures and checked for the appropriate dissection and complications occurred. Analysis was made upon the residents' performance of their first four septoplasties and eight nasal sides against their subsequent performance of the same. Final procedures presented better outcomes than the initial ones on every step of them. Results were measured by means of decrease of time (P < 0.0001) and complications, showing no major complications on the latest ones. Sheep's head is a suitable substitute for the cadaveric human head, to obtain the surgical skills needed for FESS procedures. Sheep's nasal cavity allows gaining dexterity and it is an easy model to obtain.

  15. Oral Clonidine Premedication Decreases Intraoperative Bleeding in Patients Undergoing Endoscopic Sinus Surgery

    Directory of Open Access Journals (Sweden)

    M Jabalameli

    2005-01-01

    Full Text Available Background: The antihypertensive drug, clonidine, is a centrally acting alpha 2 agonist, useful as a premedication because of its sedative and analgesic properties. We examined the effect of clonidine given as an oral premedication in producing a bloodless surgical field in patients undergoing endoscopic sinus surgery. We also evaluated the relation between bleeding volume and consumption of fentanyl and hydralazine to control hypotension. Methods: This prospective double - blinded clinical trial was performed on 113 patients (ASA I, ASA II. Fifty-two patients received oral clonidine (5 µg/kg while the other 61 patients received placebo. During general anesthesia, the hemodynamic endpoint of the anesthetic management was maintenance of hypotension (MAP at 70 mmHg for producing a bloodless surgical field. The direct control of MAP was attained with inspired concentration increments of halothane up to maximum of 1.5 vol % as needed. When it was unsuccessful, an intravenous fentanyl bolus of 2 µg/kg was also added. When both drugs failed, hydralazine , was given intravenously as a bolus and intermittently, 0.1mg/kg up to a maximum dose of 40 mg. Intraoperative bleeding was assessed on a six – point scale from 0 (= no bleeding to 5 (= severe bleeding. Data were compared with chisquare test, fisher's exact test and Student t-test. Results: There was less bleeding volume in the clonidine group (mean ± SD than in the placebo group (144 ± 75 Vs 225 ± 72 ml, P<0.05. Frequency of bleeding severity scores 3 and 4 (troublesome with repeated suction were lower in the clonidine group than in the placebo group (12% Vs 35%, P< 0.05. Fentanyl requirement was significantly lower (112 ± 18 Vs 142 ± 21 µg, P < 0.05 in the clonidine group. Hydralazine requirement was significantly lower (0.45 ± 1.68 Vs 2.67 ± 4.33 Conclusion: Premedication with oral clonidine reduces bleeding in endoscopic sinus surgery and also decreases fentanyl, and hydralazine

  16. Clinical Efficacy of endoscopic sinus surgery for chronic sinusitis%鼻内镜手术治疗慢性鼻窦炎的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    向孝军

    2016-01-01

    Objective To investigate the clinical efficacy of endoscopic sinus surgery for chronic sinusitis treatment.Methods 50 patients with chronic sinusitis selected from January 2013 to December 2014 in our hospital, these 50 cases were treated with endoscopic sinus surgery.Results Endoscopic sinus surgery for chronic sinusitis, surgery time, shorter postoperative hospital stay, treatment of high efficiency, low rate of complications and recurrence, and can improve the quality of life of patients.Conclusion The clinical efficacy of endoscopic sinus surgery for chronic sinusitis significantly, can be clinical.%目的:探讨鼻内镜手术治疗慢性鼻窦炎的临床疗效。方法:选自2013年1月至2014年12月我院收治的慢性鼻窦炎患者50例,对这50例患者采用鼻内镜手术治疗。结果:采用鼻内镜手术治疗慢性鼻窦炎手术时间、术后住院时间较短,治疗的有效率高,并发症及复发率低,且能够提高患者的生活质量。结论:鼻内镜手术治疗慢性鼻窦炎的临床疗效显著,可进行临床推广。

  17. 鼻内镜鼻窦手术后额窦炎13例报告%Clinical Analysis of Frontal Sinusitis after Endoscopic Sinus Surgery

    Institute of Scientific and Technical Information of China (English)

    刘春万; 张雁; 何淑琼

    2015-01-01

    目的 探讨功能性鼻内镜手术( FESS)后复发及继发性额窦炎的原因及二次手术方法. 方法 回顾性分析13例(16例)FESS后额窦炎患者的临床资料. 患者第二次手术均通过鼻内镜检查及鼻窦CT扫描确诊. 结合患者前期手术临床资料,其中复发性额窦炎8例,共9侧,继发性额窦炎5例,共7侧,13例均经第二次手术治疗. 结果 复发性额窦炎8例中,额窦引流通道瘢痕粘连致额窦口狭窄、闭锁6例;中鼻甲前端与外侧壁广泛性粘连1例;息肉复发堵塞窦口1例;5例继发性额窦炎中,因中鼻甲前端与外侧壁瘢痕粘连4例、6侧,因额隐窝息肉复发堵塞窦口1例. 13例患者经第二次手术后,按海口标准治愈12例,再复发1例. 结论 额窦引流通道瘢痕粘连特别是中鼻甲前端与外侧壁广泛性粘连、息肉复发是复发性额窦炎的主要原因. 再次手术是治疗复发性、继发性额窦炎重要手段之一.%Objective To explore the main causes and treatments of recurrent and secondary frontal sinusitis after endo-scopic sinus surgery. Methods Thirteen patients with frontal sinusitis were involved in this study. All of these patients had re-ceived nasal endoscopic surgeries before. Before receiving a re-operation,they were diagnosed according the results of endoscopy and CT scan with a recurrent headache as the commonest manifestation. Their clinical date of the first operations were reviewed. Eight recurrent and 5 secondary cases of frontal sinusitis were diagnosed. Results Among the recurrent sinusitis cases,6 patients were found had the problem of stenosis or obstruction of the frontal sinus drainage channel. One patient' s middle turbinate was ex-tensive adhered with the lateral nasal wall,while another one patients had the sinus polyps blocked the opening. The similar results were founded among the other 5 patients. Four cases were observed the extensive adhesion and the rest of one case had the sinus polyps

  18. Radiologic anatomy of the paranasal sinuses in computed tomography for the need of the endoscopic surgery; Anatomia radiologiczna zatok przynosowych w obrazach tomografii komputerowej dla potrzeb chirurgii endoskopowej

    Energy Technology Data Exchange (ETDEWEB)

    Boguslawska-Staniaszczyk, R.; Krzeski, A.; Mastalerski, J. [Centralny Szpital MSW, Warsaw (Poland)]|[Akademia Medyczna, Warsaw (Poland)

    1994-12-31

    Computed tomography is the most useful method in the endoscopic surgery of the nose and paranasal sinuses. CT examination is necessary for planing and the extent of the surgery. In this publication the method of CT examination and radiological anatomy of the nose and paranasal sinuses is described. (author). 15 refs, 10 figs.

  19. Outcome of Endoscopic Sinus Surgery in the Treatment of Chronic Rhinosinusitis.

    Science.gov (United States)

    Rahman, T; Alam, M M; Ahmed, S; Karim, M A; Rahman, M; Wahiduzzaman, M

    2016-04-01

    This prospective study was conducted to compare the outcome of endoscopic sinus surgery (ESS) using SNOT-20 score chart (subjective) and Lund & Kennedy scoring chart (objective) and carried out in the Department of Otolaryngology & Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Dhaka Medical College Hospital (DMCH) & Shaheed Suhrawardy Medical College Hospital (ShSMCH) from July 2010 to March 2012. Total 73 admitted cases were selected purposively for ESS, male 53(72.60%) and female 20(27.40%). Among the study participants 10(13.7%) had chronic rhinosinusitis with bilateral polyposis and 26(35.62%) had chronic rhinosinusitis with unilateral polyposis and 12(16.44%) had bilateral chronic rhinosinusitis without polyposis and 25(34.25%) had unilateral chronic rhinosinusitis without polyposis. Surgical procedures done among the patients were Uncinectomy (infundibulectomy), Middle Meatal Antrostomy; Anterior Ethmoidectomy; Sphenoidotomy, Associated septoplasty and no significant per or post operative complications were noted. In Chronic rhinosinusitis (CRS) with polyposis pre operative SNOT-20 mean and SD 1.322±0.341 and post ESS snot-20 mean and SD 0.3472±0.0755, CRS without polyposis pre operative SNOT-20 mean and SD 0.9297±0.86 and post ESS SNOT-20 mean and SD 1986±0.0558. In CRS with polyposis pre operative Lund & Kennedy score of endoscopic assessment, mean and SD 5.333±2.255 and post ESS mean and SD 1.31±1.009. In CRS without polyposis pre op Lund & Kennedy score mean and SD 3.108±1.074 and post ESS mean and SD 0.76±0.641.Post ESS SNOT-20 in CRS with Polyposis, 't' test result was 27.58 which was significant (ptreatment of CRS with or without polyposis had statistically significant role. Symptomatic relief and quality of life improvement after ESS was compared by improvement in post operative scores of SNOT-20 & Lund-Kennedy score of endoscopic assessment. Post operative lower values were considered to be better improvement

  20. Feasibility of dexmedetomidine assisting sevoflurane for controlled hypotension in endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    Guang-jie GAO

    2012-01-01

    Full Text Available Objective  To explore the feasibility of dexmedetomidine as an adjuvant of sevoflurane for controlled hypotension in endoscopic sinus surgery. Methods  Forty-eight patients (ASA Ⅰor Ⅱ scheduled for endoscopic sinus surgery were randomly assigned into two groups (n=24: control group (group I and dexmedetomidine group (group Ⅱ. In both groups, intravenous injection of midazolam, propofol, fentanyl, and atracurium besilate was given to induce anesthesia, and propofol, fentanyl, atracurium besilate, together with sevoflurane inhalation were used to maintain anesthesia. The radial artery was cannulated to monitor the invasive mean arterial pressure (MAP. Controlled hypotension was induced by adjusting the sevoflurane concentration in group Ⅰ. In group Ⅱ, within 15min to 30min before the induction of anesthesia, dexmedetomidine was administered in a dose of 0.8μg/kg via intravenous infusion pump, then maintained at 0.4μg/(kg·h. Sevoflurane concentration was adjusted to maintain the target blood pressure at the beginning of surgery. The MAP was maintained at 65-75mmHg up to the end of operation. Meanwhile, the heart rate (HR, MAP, epinephrine (E, and norepinephrine (NE concentrations were recorded at the time of induction of anesthesia (T0, beginning of controlled hypotension (T1, 30min after controlled hypotension (T2, and at the time when extubation was performed (T3. Blood gas analysis and determination of lactic acid concentration were conducted using the blood drawn from the radial artery during the operation. The surgical field quality was assessed based on Fromme scores of surgical field quality (SSFQ. Meanwhile, the dose of sevoflurane, propofol, and fentanyl, MAP, the recovery time of anesthesia, and the incidence rate of untoward effects were recorded. Results  The doses of propofol, fentanyl and sevoflurane, and MAC value in group Ⅱwas significantly diminished compared with group Ⅰ(P<0.01. In addition, the surgical

  1. Administering of pregabalin and acetaminophen on management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery.

    Science.gov (United States)

    Rezaeian, Ahmad

    2017-08-08

    Management of postoperative pain is a common problem in endoscopic sinus surgery. The objective of this study is the evaluation of pregabalin and acetaminophen effects on the management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery (FESS). In this clinical trial, double-blinded study, 70 patients with nasal polyposis who have indication of FESS were enrolled to this study. After operation, patients were divided randomly into pregabalin and acetaminophen therapy groups. The pregabalin group (n = 35) was treated under pregabalin 50 mg TDS and the acetaminophen group (n = 35) was treated under tablet acetaminophen 500 mg/6 h. Each group was administered for 3 d. The visual analogue scale (VAS) was measured in onset, 12, 24, 48 and 72 h after surgery. All data were entered into SPSS software (SPSS Inc., Chicago, IL) and appropriate statistical tests were assessed to every relation. In this study, there was no significant difference between two groups according to VAS in onset (p = .37); however, VAS in 12, 24, 48 and 72 h after operation was significantly lower in the pregabalin group compared with the acetaminophen group (p acetaminophen group (p acetaminophen on the management of postoperative pain in the patients with nasal polyposis undergoing functional endoscopic sinus surgery.

  2. Sinonasal imaging after Caldwell-Luc surgery: MDCT findings of an abandoned procedure in times of functional endoscopic sinus surgery

    Energy Technology Data Exchange (ETDEWEB)

    Nemec, Stefan Franz; Peloschek, Philipp; Koelblinger, Claus; Mehrain, Sheida; Krestan, Christian Robert; Czerny, Christian [Department of Radiology, Division of Neuroradiology and Musculoskeletalradiology, Medical University of Vienna, Waehringerguertel 18-20, 1090 Vienna (Austria)

    2009-04-15

    Background and purpose: Today, functional endoscopic sinus surgery (FESS) is performed in most of the patients with sinonasal inflammatory disease. The postoperative imaging findings of FESS in multidetector computed tomography (MDCT) considerably differ from those of historic Caldwell-Luc (CL) maxillary sinus surgery which is an uncommon procedure today. Thus, the postoperative CL imaging findings may lead to diagnostic confusion and misinterpretation. Therefore, this study explicitly presents the MDCT findings of post-CL patients which have not been described previously. Methods: Twenty-eight patients with clinically suspected sinusitis and documented history of CL-procedure underwent 16 row MDCT (MDCT Mx8000 IDT Philips) with multiplanar reconstructions of the paranasal sinuses in the axial plane. The following parameters were used: 140 kV, 50 mAs; 16 mm x 0.75 mm detector collimation; 1 mm reconstructed slice thickness; 0.5 mm increment. The studies were reconstructed with a bone algorithm (W3000/L600; 1 mm slice thickness) in axial plane and coronal plane (3 mm slice thickness). The images were retrospectively evaluated for the presence of normal surgery-related and pathological findings. Results: Surgery-related imaging characteristics presented as follows: an anterior and a medial bony wall defect and sclerosis and sinus wall thickening were observed in all 28/28 cases (100%). Collaps of the sinus cavity was seen in 26/28 cases (92.9%). Furthermore, inflammatory disease of the operated sinus(es) was found in 23/28 cases (82.1%): 14/28 patients (50%) had inflammatory mucosal thickening of the operated sinus(es) as well as of other sinonasal cavities and 9/28 patients (32.1%) had inflammatory mucosal thickening limited to the operated sinus(es). A postoperative mucocele was depicted in 3/28 cases (10.7%). 2/28 patients (7.1%) showed neither maxillary nor other mucosal swelling. Conclusion: MDCT with multiplanar reconstructions is a precise method to evaluate

  3. The Effect of Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients With Concurrent Asthma

    Directory of Open Access Journals (Sweden)

    Taheri

    2016-07-01

    Full Text Available Background Chronic rhinosinusitis (CRS and asthma are among the most important health-related conditions with evident socio-economic effects. The relationship between asthma and CRS has been considered in medical references for centuries. Previous studies have shown that treatment interventions targeting disease in one part of the airway are effective for general asthma management. However, the effect of endoscopic sinus surgery (ESS in CRS patients with concurrent asthma remains controversial. Therefore, we aimed to assess the effects of ESS on improvement of asthma in CRS patients with concurrent asthma. Objectives The aim of this study was to evaluate the impact of ESS on asthma in CRS patients. Methods Twenty-five CRS patients with asthma who met our inclusion criteria after taking a complete history underwent physical examination and diagnostic nasal endoscopy, and the asthma control test (ACT questionnaire was administered to them. Six months after ESS, the patients’ asthma was again assessed using the ACT questionnaire. Results Overall, the mean ACT score significantly increased from 12.56 at the baseline to 20.71 after a six-month follow up period (0.001. Conclusions Given the remarkable improvement in asthma control levels, ESS can be considered a useful method for treating CRS patients suffering from asthma.

  4. CLONIDINE PREMEDICATION AS A DESIRABLE PART OF HYPOTENSIVE ANAESTHESIA FOR FUNCTIONAL ENDOSCOPIC SINUS SURGERY

    Directory of Open Access Journals (Sweden)

    Praveen

    2016-04-01

    Full Text Available BACKGROUND Clonidine an ideal agent for hypotensive anaesthesia, also attenuates stress response to laryngoscopy, decreases requirement of inhalational anaesthetic agents, decreases postoperative analgesic requirements, prevents post-operative shivering. MATERIAL AND METHODS 60 patients under 16-60 years age group posted for functional endoscopic sinus surgery (FESS were randomly divided into 2 groups of 30 each. Placebo group (Group P received 20 mL normal saline intravenously and Clonidine group (Group C received 2.5 micrograms Clonidine per kilogram body weight in 20 mL saline intravenously 20 mins before surgery. Haemodynamic variability during surgery, intraoperative inhalational agent requirement and perioperative bleeding as assessed by surgeon, postoperative analgesic requirement and post-operative shivering were compared between two groups. RESULTS There was statistically significant reduction in heart rate, systolic blood pressure, diastolic blood pressure and mean blood pressure in Group C compared to Group P. There was statistically significant decrease in requirement of Isoflurane, decreased bleeding from surgical site, decreased analgesic consumption and nil incidence of postoperative shivering in Group C compared to Group P. CONCLUSION Clonidine is an ideal agent for hypotensive anaesthesia as it has got other favourable effects along with controlled hypotension, as it was observed in this study

  5. Comparison of surgical condition in endoscopic sinus surgery using remifentanil combined with propofol, sevoflurane, or desflurane.

    Science.gov (United States)

    Yoo, Hyung-Seok; Han, Jin Hee; Park, Sung Wook; Kim, Keon Sik

    2010-12-01

    Various maneuvers are commonly used to achieve the ideal operative field necessary for successful endoscopic sinus surgery (ESS). There are a few contradictory reports on this subject and the consensus is that propofol anesthesia results in a better or similar surgical field and less or similar amount of bleeding than volatile anesthesia. The aim of this study was to compare the surgical field in patients in whom intravenous anesthesia is used as opposed to balanced general anesthesia. SIXTY PATIENTS UNDERGOING ESS WERE RANDOMLY ASSIGNED INTO THREE GROUPS, EACH OF WHICH USED A DIFFERENT TYPE OF ANESTHESIA: propofol/remifentanil (PRO/REM) group, sevoflurane/remifentanil (SEV/REM) group, and desflurane/remifentanil (DES/REM) group. We aimed to maintain the intraoperative mean blood pressure (MBP) at 65 mmHg and the heartrate (HR) at about 75 beats per minute. The quality of visibility of the surgical field was graded, using a validated scoring system, 60 minutes after the start of the operation. All groups had a similar MBP and mean HR at 60 minutes after the operation started. There was no significant differences among the three groups for surgical grade score (P = 0.83). In this comparative study of three anesthetic combinations (PRO/REM, SEV/REM, and DES/REM) in patients undergoing ESS with controlled BP and HR, we did not observe any significant differences in the surgical grade scores.

  6. Evaluation of piroxicam-beta-cyclodextrin as a preemptive analgesic in functional endoscopic sinus surgery.

    Science.gov (United States)

    Keleş, G T; Topçu, I; Ekici, Z; Yentür, A

    2010-08-01

    The preemptive analgesic efficacy and adverse effects of preoperatively administered piroxicam-beta-cyclodextrin for post-endoscopic sinus surgery pain was determined in a prospective, double-blind, randomized, clinical study. Seventy-five American Society of Anesthesiologists status I-II patients, aged 18-65 years, were divided into three groups with similar demographic characteristics: group 1 received 20 mg piroxicam-beta-cyclodextrin, group 2 received 40 mg piroxicam-beta-cyclodextrin and group 3 received placebo orally before induction of general anesthesia. A blinded observer recorded the incidence and severity of pain at admission to the post-anesthesia care unit (PACU), at 15, 30, and 45 min in the PACU, and 1, 2, 4, 6, and 24 h postoperatively. All patients received patient-controlled morphine analgesia during the postoperative period and consumption was recorded for 24 h. During the PACU period, mean visual analogue scale values were significantly lower in groups 1 and 2 compared to group 3 (P piroxicam-beta-cyclodextrin effectively reduced analgesic consumption, and 40 mg of the drug was more effective than 20 mg piroxicam-beta-cyclodextrin without side effects during the postoperative period.

  7. Concurrent functional endoscopic sinus surgery and septorhinoplasty: using evidence to make clinical decisions.

    Science.gov (United States)

    Patel, Zara M; Setzen, Michael; Sclafani, Anthony P; Del Gaudio, John M

    2013-06-01

    Concurrent septorhinoplasty (SRP) and functional endoscopic sinus surgery (FESS) has been a controversial topic in the literature over the last decade. Warnings and admonitions about the risks of performing these procedures together in a single surgery are both published and voiced at national meetings. Although pros and cons have been discussed in the literature, there have been no guidelines published based solely on a review of the level of evidence. A systematic review of the literature was performed and the Clinical Practice Guideline Manual, Conference on Guideline Standardization (COGS), and the Appraisal of Guidelines and Research Evaluation (AGREE) instrument recommendations were followed. Study inclusion criteria were an adult population >18 years old, description or implication of study design available, concurrent FESS and SRP performed without additional procedures, and report of complications included in the study. We identified and evaluated the literature meeting those criteria: 11 retrospective studies. The literature was reviewed for both quality of research design as well as benefit and harm of the proposed interventions. If a patient is in need of FESS and SRP, either for functional or cosmetic reasons, and is found on the risk matrix to either have low or moderate risk, that patient is a good candidate for a concurrent procedure. If the patient is found to have higher risk, it is not an absolute contraindication, but the surgeon must use best clinical judgment when deciding to move forward and must counsel the patient preoperatively about possible increased risks. © 2013 ARS-AAOA, LLC.

  8. Comparison of Isoflurane and Sevoflurane for Controlled Hypotension in Endoscopic Sinus Surgeries and Tympanomastoidectomy

    Directory of Open Access Journals (Sweden)

    B. Yazdi

    2014-07-01

    Full Text Available Introduction & Objective: Even a little bleeding can adversely affect the surgeon's ability to visualize the region to be operated in ENT operations. The aim of this study is to compare the effects of isoflurane and sevoflurane on hemodynamics and bleeding in controlled hypoten-sion. Materials & Methods: This study was a double-blind clinical trial. Ninety patients who were candidates for endoscopic sinus surgery and tympanomastoidectomy in Amirkabir hospital of Arak were randomly assigned into two groups of isoflurane and sevoflurane. Remifentanil was infused at 0.1 µg/kg/min for both groups during surgery and the amount of bleeding and hemodynamic parameter were recorded. The data was analyzed by SPSS-20 and ANOVA statistical test. Results: Underlying and hemodynamic variables were similar between the two groups preop-eratively. The amount of blood loss during surgery showed that there were no significant dif-ferences between the two groups (P=0.802 and no significant differences in hemodynamic variables (heart rate, systolic/diastolic blood pressure and arterial oxygen saturation were observed between the two groups during the surgery. Conclusion: It is concluded that there is no difference between sevoflurane and isoflurane in controlled hypotension. Thus, using these drugs in operations with excessive bleeding is rec-ommended. (Sci J Hamadan Univ Med Sci 2014; 21(2:85-91

  9. Readability assessment of Internet-based patient education materials related to endoscopic sinus surgery.

    Science.gov (United States)

    Cherla, Deepa V; Sanghvi, Saurin; Choudhry, Osamah J; Liu, James K; Eloy, Jean Anderson

    2012-08-01

    Numerous professional societies, clinical practices, and hospitals provide Internet-based patient education materials (PEMs) to the general public, but not all of this information is written at a reading level appropriate for the average patient. The National Institutes of Health and the US Department of Health and Human Services recommend that PEMs be written at or below the sixth-grade level. Our purpose was to assess the readability of endoscopic sinus surgery (ESS)-related PEMs available on the Internet and compare readability levels of PEMs provided by three sources: professional societies, clinical practices, and hospitals. A descriptive and correlational design was used for this study. The readability of 31 ESS-related PEMs was assessed with four different readability indices: Flesch-Kincaid Grade Level (FKGL), Flesch Reading Ease Score (FRES), Simple Measure of Gobbledygook (SMOG), and Gunning Frequency of Gobbledygook (Gunning FOG). Averages were evaluated against national recommendations and between each source using analysis of variance and t tests. The majority of PEMs (96.8%) were written above the recommended sixth-grade reading level, based on FKGL (P Society, Inc.

  10. Sinusitis

    Science.gov (United States)

    ... the result of an infection from a virus, bacteria, or fungus. Causes The sinuses are air-filled spaces in ... than 3 months. It may be caused by bacteria or a fungus. The following may increase the risk that an ...

  11. Computer aided surface representation

    Energy Technology Data Exchange (ETDEWEB)

    Barnhill, R.E.

    1989-02-09

    The central research problem of this project is the effective representation and display of surfaces, interpolating to given information, in three or more dimensions. In a typical problem, we wish to create a surface from some discrete information. If this information is itself on another surface, the problem is to determine a surface defined on a surface,'' which is discussed below. Often, properties of an already constructed surface are desired: such geometry processing'' is described below. The Summary of Proposed Research from our original proposal describes the aims of this research project. This Summary and the Table of Contents from the original proposal are enclosed as an Appendix to this Progress Report. The broad sweep from constructive mathematics through algorithms and computer graphics displays is utilized in the research. The wide range of activity, directed in both theory and applications, makes this project unique. Last month in the first Ardent Titan delivered in the State of Arizona came to our group, funded by the DOE and Arizona State University. Although the Titan is a commercial product, its newness requires our close collaboration with Ardent to maximize results. During the past year, four faculty members and several graduate research assistants have worked on this DOE project. The gaining of new professionals is an important aspect of this project. A listing of the students and their topics is given in the Appendix. The most significant publication during the past year is the book, Curves and Surfaces for Computer Aided Geometric Design, by Dr. Gerald Farin. This 300 page volume helps fill a considerable gap in the subject and includes many new results on Bernstein-Bezier curves and surfaces.

  12. Comparison of the effects of magnesium sulphate and dexmedetomidine on surgical vision quality in endoscopic sinus surgery: randomized clinical study

    Directory of Open Access Journals (Sweden)

    Akcan Akkaya

    2014-12-01

    Full Text Available Background and objectives: Even a small amount of bleeding during endoscopic sinus surgery can corrupt the endoscopic field and complicate the procedure. Various techniques, including induced hypotension, can minimize bleeding during endoscopic sinus surgery. The aim of this study was to compare the surgical vision quality, haemodynamic parameters, postoperative pain, and other effects of magnesium, a hypotensive agent, with that of dexmedetomidine, which was initially developed for short-term sedation in the intensive care unit but also is an alpha 2 agonist sedative. Method: 60 patients between the ages of 18 and 45 years were divided into either the magnesium group (Group M or the dexmedetomidine group (Group D. In Group M, magnesium sulphate was given at a pre-induction loading dose of 50 mg kg−1 over 10 min and maintained at 15 mg kg−1 h−1; in Group D, dexmedetomidine was given at 1 mcg kg−1 10 min before induction and maintained at 0.6 mcg kg−1 h−1. Intraoperatively, the haemodynamic and respiratory parameters and 6-point intraoperative surgical field evaluation scale were recorded. During the postoperative period, an 11-point numerical pain scale, the Ramsay sedation scale, the nausea/vomiting scale, the adverse effects profile, and itching parameters were noted. Results: Group D showed a significant decrease in intraoperative surgical field evaluation scale scale score and heart rate. The average operation time was 50 min, and Group M had a higher number of prolonged surgeries. No significant difference was found in the other parameters. Conclusions: Due to its reduction of bleeding and heart rate in endoscopic sinus surgery and its positive impacts on the duration of surgery, we consider dexmedetomidine to be a good alternative to magnesium.

  13. Anatomy, classification of intersinus septal cell and its clinical significance in frontal sinus endoscopic surgery in Chinese subjects

    Institute of Scientific and Technical Information of China (English)

    WANG Min; YUAN Fei; QI Wei-wei; CHENG Jye-yuan; YUAN Xiao-pei; HAN Lin; XING Zhi-min

    2012-01-01

    Background Intersinus septal cell (ISSC) is not a very uncommon frontal recess cell.But it is poorly described in literature.The clinical significance of this anatomic variant still remains unclear.The purpose of this study was to clarify the anatomy,classification of ISSC and its clinical significance in Chinese subjects.Methods We prospectively identified ISSC in 200 consecutive subjects who had undergone computed tomography (CT) scans:120 without frontal sinusitis (group 1) and 80 with frontal sinusitis (group 2).The ISSC was classified into two types:Type I ISSC communicated with frontal sinuses,type Ⅱ ISSC communicated with frontal recess.The patients of frontal sinusitis had undergone functional endoscopic sinus surgery with the assistance of the classification of ISSC.Statistical analysis was performed to correlate the ISSC and its type to the presence of frontal sinusitis.Results The ISSC was obvious when reviewing the coronal and axial CT scans.Of the 200 CT scans reviewed,ISSC were present in 90 (45%).Of the 120 scans in group 1,ISSC were present in 49 (41%),among which type I ISSC was in 22 (18%) and type Ⅱ was in 27 (23%).Of the 80 scans in group 2,ISSC was present in 41 (51%),among which type Ⅰ ISSC was in 16 (20%) and type Ⅱ was in 25 (31%).There were no statistically significant differences about the frequency distribution of total ISSC,type Ⅰ and Ⅱ ISSC between group 1 and group 2.Conclusions The prevalence of ISSC was very high in Chinese patients.The classification of ISSC was helpful for surgeon to operate according to whether it communicated with frontal sinus or frontal recess.The type Ⅱ ISSC could be relatively easily removed from frontal recess.

  14. Long-term results of endoscopic sinus surgery-oriented treatment for chronic rhinosinusitis with asthma.

    Science.gov (United States)

    Chen, Feng-Hong; Zuo, Ke-Jun; Guo, Yu-Biao; Li, Zhi-Ping; Xu, Geng; Xu, Rui; Shi, Jian-Bo

    2014-01-01

    The aims of this study were to evaluate the efficacy of functional endoscopic sinus surgery (FESS)-oriented multimodality treatment in chronic rhinosinusitis (CRS) patients with asthma and its impact on asthma. Prospective, nonrandomized cohort. Twenty-seven CRS patients with asthma who underwent FESS with postoperative topical corticosteroid spray were evaluated preoperatively; 25 of them were evaluated 1 year and 3 years postoperatively. CRS was evaluated by visual analogue scale, clinical control of CRS, and objective measurement endoscopy Lund-Kennedy scores. Asthma was assessed by subjective asthma control test and asthma control level, also by objective antiasthma medication use and pulmonary function tests. VAS scores of general symptoms (8.09 ± 0.87 preoperatively) were significantly improved at 1 year (2.94 ± 2.21) and 3 years (3.77 ± 2.16) postoperation (P = .000). No difference in these items was found between 1 year and 3 years (P = .463). Endoscopy Lund-Kennedy scores at 1 year (4.34 ± 3.09) and 3 years (5.80 ± 3.38) postoperatively were significantly better (9.33 ± 2.03 preoperatively, P = .000), and there was no difference between 1 year and 3 years of follow-up (P > .05). Significantly, asthma control level improved postoperatively (P = .025). However, antiasthma drug and pulmonary function showed no significant change postoperatively (P > .05). FESS-oriented multimodality treatment improves CRS with asthma significantly and persistently. Asthma control level improved. Antiasthma medication use and pulmonary function remained stable. © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

  15. Comparison between magnesium sulfate and dexmedetomidine in controlled hypotension during functional endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    Adnan Bayram

    2015-02-01

    Full Text Available BACKGROUND AND OBJECTIVES: It is crucial to decrease bleeding during functional endoscopic sinus surgery. Our primary goal was to investigate the effects of magnesium sulfate and dexmedetomidine used for controlled hypotension on the visibility of the surgical site. METHODS: 60 patients aged between 18 and 65 years were enrolled. In the magnesium sulfate group (Group M, patients were administered 40 mg/kg magnesium sulfate in 100 mL saline solution over 10 min as the intravenous loading dose 10 min before induction, with a subsequent 10-15 µg/kg/h infusion during surgery. In the dexmedetomidine group (Group D, patients were administered 1 µg/kg dexmedetomidine in 100 mL saline solution as the loading dose 10 min before surgery and 0.5-1 µg/kg/h dexmedetomidine during surgery. Deliberate hypotension was defined as a mean arterial pressure of 60-70 mmHg. RESULTS: Bleeding score was significantly decreased in Group D (p = 0.002. Mean arterial pressure values were significantly decreased in Group D compared to that in Group M, except for the initial stage, after induction and 5 min after intubation (p < 0.05. The number of patients who required nitroglycerine was significantly lower in Group D (p = 0.01 and surgeon satisfaction was significantly increased in the same group (p = 0.001. Aldrete recovery score ≥9 duration was significantly shorter in Group D (p = 0.001. There was no difference between the two groups in terms of recovery room verbal numerical rating scale. CONCLUSIONS: Dexmedetomidine can provide more effective controlled hypotension and thus contribute to improved visibility of the surgical site.

  16. Evaluation of piroxicam-β-cyclodextrin as a preemptive analgesic in functional endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    G.T. Keleş

    2010-08-01

    Full Text Available The preemptive analgesic efficacy and adverse effects of preoperatively administered piroxicam-β-cyclodextrin for post-endoscopic sinus surgery pain was determined in a prospective, double-blind, randomized, clinical study. Seventy-five American Society of Anesthesiologists status I-II patients, aged 18-65 years, were divided into three groups with similar demographic characteristics: group 1 received 20 mg piroxicam-β-cyclodextrin, group 2 received 40 mg piroxicam-β-cyclodextrin and group 3 received placebo orally before induction of general anesthesia. A blinded observer recorded the incidence and severity of pain at admission to the post-anesthesia care unit (PACU, at 15, 30, and 45 min in the PACU, and 1, 2, 4, 6, and 24 h postoperatively. All patients received patient-controlled morphine analgesia during the postoperative period and consumption was recorded for 24 h. During the PACU period, mean visual analogue scale values were significantly lower in groups 1 and 2 compared to group 3 (P < 0.05. During the postoperative period, morphine consumption was 3.03 ± 2.54, 2.7 ± 2.8, and 5.56 ± 3.12 mg for each group, respectively (P < 0.05. As a side effect, bleeding was observed in groups 1 and 3, nausea and vomiting in all groups, and edema only in group 3. However, no significant differences were detected in any of the parameters analyzed, which also included epigastric pain, constipation/diarrhea and headache. Similar hematological test results were obtained for all groups. Preemptive administration of piroxicam-β-cyclodextrin effectively reduced analgesic consumption, and 40 mg of the drug was more effective than 20 mg piroxicam-β-cyclodextrin without side effects during the postoperative period.

  17. 内镜经鼻海绵窦病变活检术%Endoscopic transnal biopsy for diagnosis of cavernous sinus lesions

    Institute of Scientific and Technical Information of China (English)

    刘海生; 张秋航; 陈国强; 王世杰; 左焕琮

    2009-01-01

    Objective To study the surgical technique of endoscopic transnasal biopsy for the diagnosis of cavernous sinus lesions.Methods Ten patients with cavernous sinus lesions were diagnosed by endoscopic transnasal biopsy.Retrospectively the clinical data of 10 patients were reviewed.Results The accuracy of diagnosis with this technique WSS 100%.Postoperative results included:5 patients with malignant tumors received radiotherapy,1 pauent with meningioma underwent yknife treatment,and 1 patient received antifungal therapy.2 patients with benign lesion and 1 patient underwent local radiotherapy were followed.Postoperative complications included:one patient with internal carotid artery injury was treated by interventional ballon occlusion and one with transient eerebrospinal leakage.Conclusion Endoscopic transrmsal biopsy is an effective.safe and mini-invssive approach for the diagnosis of cavernous sinus lesions.

  18. Endoscopically assisted procedure for removal of a foreign body from the maxillary sinus and contemporary endodontic surgical treatment of the tooth

    Directory of Open Access Journals (Sweden)

    Sembronio Salvatore

    2006-11-01

    Full Text Available Abstract There have been reports on the migration of teeth or implants into the maxillary sinus. We know of only one report on the migration of a gutta-percha point that had been used to fill a root canal into the ethmoid sinus. We report such a case treated with an endoscopically assisted procedure for removal of the foreign body and contemporary endodontic surgical treatment of the tooth.

  19. Computer-Aided Modeling Framework

    DEFF Research Database (Denmark)

    Fedorova, Marina; Sin, Gürkan; Gani, Rafiqul

    development and application. The proposed work is a part of the project for development of methods and tools that will allow systematic generation, analysis and solution of models for various objectives. It will use the computer-aided modeling framework that is based on a modeling methodology, which combines....... In this contribution, the concept of template-based modeling is presented and application is highlighted for the specific case of catalytic membrane fixed bed models. The modeling template is integrated in a generic computer-aided modeling framework. Furthermore, modeling templates enable the idea of model reuse...... are generated through the template in ICAS-MoT and translated into a model object. Once in ICAS-MoT, the model is numerical analyzed, solved and identified. A computer-aided modeling framework integrating systematic model derivation and development tools has been developed. It includes features for model...

  20. 鼻内窥镜手术治疗非侵袭性真性上颌窦炎的疗效观察%Curative effect of endoscopic sinus surgery on treatment of non-invasive fungal maxillary sinusitis

    Institute of Scientific and Technical Information of China (English)

    段宗瑾

    2009-01-01

    Objective To explore the clinical efficacy of endoscopic sinus surgery on the treatment of non-invasive fangal the maxillary sinusitis. Methods 21 patients with non-invasive fungal maxillary sinusitis patients were given endoscopic sinus surgery. Completely remove of the nasal cavity and sinus disease, fully open, washing si-nusos and give nasal endoscopy on a regular fine. Results Follow-up of 6 months to 4 years,18 cases of cure,1 case of loss of information. 2 case of relapse. Cases of recurrence were cured by endoscopic sinus dressing. Conclusion Endoseopie sinus surgery is an effective measure on trentment of non-invasive fungal maxillary sinuses.%目的 探讨鼻内窥镜手术在治疗非侵袭性真菌性上颌窦炎的临床疗效.方法 对21例非侵袭性真菌性上颌窦炎患者行鼻内窥镜手术.彻底清除鼻腔、鼻窦病灶,充分开放、冲洗鼻窦,并定期行鼻内窥镜检查.结果 随访6个月至4年,治愈18例,失访1例,复发2例.复发病例经鼻内窥镜换药后治愈.结论 鼻内窥镜手术是治疗非侵袭性真菌性上颌窦炎的有效手段.

  1. Gender-specific differences in chronic rhinosinusitis patients electing endoscopic sinus surgery.

    Science.gov (United States)

    Lal, Devyani; Rounds, Alexis B; Divekar, Rohit

    2016-03-01

    The objective of this study was to investigate gender-specific differences in chronic rhinosinusitis (CRS) patients electing endoscopic sinus surgery (ESS). This study was a retrospective review of CRS patients electing ESS (2011-2013) at a tertiary-care center. ESS was elected by 272 patients (mean age 54.6 years; 48.5% female). Mean Lund-Mackay computed tomography (CT) score was 10.9; total 22-item Sino-Nasal Outcome Test (SNOT-22) score was 41.8. Compared to men, women electing ESS had lower CT score (10.1 vs 11.7; p = 0.01) but higher total SNOT-22 score (44.9 vs 39; p = 0.02). Women reported significantly worse postnasal drainage (p embarrassment (p = 0.0021). SNOT-22 scores declined with advancing age (women, p = 0.003; men, p = 0.0005). Reduction in CT scores with age was seen only in males (p = 0.03). Stratifying by age, females aged 61 to 80 years had higher SNOT-22 scores compared to male counterparts (p = 0.04), whereas CT scores were similar. More women underwent surgery for CRS without nasal polyps (CRSsNP) (54.9%) whereas more men underwent surgery for CRS with nasal polyps (CRSwNP) (57.4%), but this difference missed statistical significance (p = 0.052). Women with CRSwNP had higher SNOT-22 scores than men (p = 0.02) for similar CT scores. Men electing ESS for CRSsNP had higher CT scores than women (p = 0.02). Women with CRSsNP aged 18 to 40 years reported higher SNOT-22 scores than men (p = 0.003), even though CT scores were lower (p = 0.005). Equivalent numbers of men and women underwent ESS for CRS. Overall, women electing ESS had higher total SNOT-22 scores and lower Lund-Mackay CT scores than men. Women reported more problems with postnasal drainage (CRS overall, CRSsNP, and CRSwNP), embarrassment (CRS overall and CRSwNP), and facial pain (CRSwNP). Gender differences in CRS are poorly understood and merit further study. © 2015 ARS-AAOA, LLC.

  2. Induced hypotension for functional endoscopic sinus surgery: A comparative study of dexmedetomidine versus esmolol

    Directory of Open Access Journals (Sweden)

    Tarek Shams

    2013-01-01

    Full Text Available Objective: A comparative study to evaluate the efficacy of dexmedetomidine as a hypotensive agent in comparison to esmolol in Functional Endoscopic Sinus Surgery (FESS. Methods: Forty patients ASA I or II scheduled for FESS were equally randomly assigned to receive either dexmedetomidine 1 μg/Kg over 10 min before induction of anesthesia followed by 0.4-0.8 μg/Kg/h infusion during maintenance (DEX group, or esmolol, loading dose 1mg/kg was infused over one min followed by 0.4-0.8 mg/kg/h infusion during maintenance (E group to maintain mean arterial blood pressure (MAP between (55-65 mmHg. General anesthesia was maintained with sevoflurane 2%-4%. The surgical field was assessed using Average Category Scale and average blood loss was calculated. Hemodynamic variables (MAP and HR; arterial blood gas analysis; plasma cortisol level; intraoperative fentanyl consumption; Emergence time and total recovery from anesthesia (Aldrete score ≥9 were recorded. Sedation score was determined at 15, 30, 60 min after tracheal extubation and time to first analgesic request was recorded. Result: Both DEX group and E group reached the desired MAP (55-65 mmHg with no intergroup differences in MAP or HR. The for the quality of the surgical filed in the range of MAP (55-65 mmHg were <=2 with no significant differences between group scores during hypotensive period. Mean intraoperative fentanyl consumption was significantly lower in DEX group than E group. Cortisol level showed no significant changes between or within groups. No significant changes were observed in arterial blood gases. Emergence time and time to achieve Aldrete score ≥9 were significantly lower in E group compared with DEX group. The sedation score were significantly lower in E group compared with DEX group at 15 and 30 minutes postoperatively. Time to first analgesic request was significantly longer in DEX group. Conclusion: Both dexmedetomidine or esmolol with sevoflurane are safe agents for

  3. Smell impairment in chronic rhinosinusitis – evaluation of endoscopic sinus surgery results and review of literature concerning olfactory function predictors.

    Science.gov (United States)

    Szaleniec, Joanna; Wróbel, Agnieszka; Stręk, Paweł; Kowalczyk, Monika; Bylica, Ewa; Przeklasa, Maria; Żyła, Małgorzata; Składzień, Jacek

    2015-01-01

    Endoscopic sinus surgery (ESS) is the treatment of choice for patients with chronic rhinosinusitis (CRS) refractory to medical therapy. ESS successfully reduces most symptoms of CRS, but its effect on olfaction is always uncertain. The aim of this study was to assess the influence of sinus surgery on olfaction and to analyze the predictors of olfactory function before and after ESS in the context of a literature review. The study group comprised of 153 patients with CRS refractory to medical treatment. The patients evaluated their olfactory function before ESS, 3-6 months after ESS (121 individuals) and 12 months after ESS (58 individuals). Statistical analysis concerned the postoperative olfactory improvement as well as the influence of various predictors on the impairment of smell before and after surgery. Olfactory dysfunction was significantly reduced after ESS. The smell impairment before and after surgery depended on different predictors. Patients with severe preoperative olfactory dysfunction and extensive pathological changes in the nose and sinuses, including nasal polyps, reported most pronounced improvement after ESS. However, severely hyposmic subjects with nasal polyposis, asthma or aspirin intolerance as well as older patients reported worse postoperative smell scores.

  4. Computer-aided translation tools

    DEFF Research Database (Denmark)

    Christensen, Tina Paulsen; Schjoldager, Anne

    2016-01-01

    The paper reports on a questionnaire survey from 2013 of the uptake and use of computer-aided translation (CAT) tools by Danish translation service providers (TSPs) and discusses how these tools appear to have impacted on the Danish translation industry. According to our results, the uptake in De...

  5. 功能性内镜鼻窦手术后不同鼻窦黏膜的转归规律%Regularity of nasal mucous transitionary course of different sinuses after functional endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    左可军; 李华斌; 史剑波; 许庚

    2012-01-01

    目的 探讨慢性鼻-鼻窦炎患者功能性内镜鼻窦手术后不同鼻窦黏膜转归的时间规律.方法 前瞻性收集77例慢性鼻-鼻窦炎患者的临床资料,在实施功能性内镜鼻窦手术后的第2周、第1、2、3、6、9、12个月采用Lund-Kennedy内镜评分方法分别对每侧鼻腔每个鼻窦进行评估,比较不同时期不同鼻窦黏膜形态的评分数值和完成上皮化比例.结果 共计154个上颌窦、154个筛窦、138个额窦和129个蝶窦纳入内镜观察与评分分析.在术后第2周,蝶窦、筛窦、上颌窦和额窦黏膜形态评分分别为(3.5±1.5)、(3.6±1.4)、(3.7±1.5)、(3.8±1.5)分,差异无统计学意义(x2=1.674,P =0.643);在术后第2、3、6、9个月,4种鼻窦黏膜的转归过程呈现明显分离趋势,依次出现黏膜评分下降拐点和上皮化比例升高峰值;在术后第12个月,蝶窦、筛窦、上颌窦、额窦评分分别为(0.4±0.1)、(0.9±0.1)、(1.4±0.2)、(2.1±0.2)分,差异有统计学意义(x2=52.691,P=0.000);且蝶窦黏膜形态评分(Z=-3.417,P =0.001)和完成上皮化的比例(x2=4.313,P=0.038)明显优于筛窦,筛窦黏膜形态评分(Z=-2.218,P=0.027)和完成上皮化比例(x2=4.292,P=0.038)明显优于上颌窦,上颌窦黏膜形态评分(Z=-2.244,P =0.025)和完成上皮化比例(x2=4.100,P =0.043)明显优于额窦.结论 功能性内镜鼻窦手术后不同鼻窦的黏膜转归存在明显时间差异,上皮化进程的先后顺序依次是蝶窦、筛窦、上颌窦和额窦.%Objectives To explore the time regularity of nasal mucous transitionary course of different sinuses after functional endoscopic sinus surgery.Methods Seventy-seven chronic rhinosinusitis patients following functional endoscopic sinus surgery were prospectively collected. The endoscopic appearances of different sinuses were respectively evaluated with Lund-Kennedy scoring system in 2 weeks,1,2,3,6,9 months,and 12 months postoperatively. Then the endoscopic scores and

  6. Nitroglycerine, esmolol and dexmedetomidine for induced hypotension during functional endoscopic sinus surgery: A comparative evaluation

    Science.gov (United States)

    Bajwa, Sukhminder Jit Singh; Kaur, Jasleen; Kulshrestha, Ashish; Haldar, Rudrashish; Sethi, Rakesh; Singh, Amarjit

    2016-01-01

    Background and Aim: Induced hypotension limits intra-operative blood loss to provide better visibility of the surgical field and diminishes the incidence of major complications during functional endoscopic sinus surgery (FESS). We aimed at comparing nitroglycerine, esmolol and dexmedetomidine for inducing controlled hypotension in patients undergoing FESS. Material and Methods: One hundred and fifty American Society of Anesthesiologists physical status I or II adult patients undergoing FESS under general anesthesia were randomly allocated to three groups of 50 patients each. Group E received esmolol in a loading and maintenance dose of 1 mg/kg over 1 min and 0.5-1.0 mg/kg/h, respectively. Group D received a loading dose of dexmedetomidine 1 μg/kg over 10 min followed by an infusion 0.5-1.0 μg/kg/h, and group N received nitroglycerine infusion at a dose of 0.5-2 μg/kg/min so as to maintain mean arterial pressure (MAP) between 60 and 70 mmHg in all the groups. The visibility of the surgical field was assessed by surgeon using Fromme and Boezaart scoring system. Hemodynamic variables, total intra-operative fentanyl consumption, emergence time and time to first analgesic request were recorded. Any side-effects were noted. The postoperative sedation was assessed using Ramsay Sedation Score. Result: The desired MAP (60-70 mmHg) could be achieved in all the three study groups albeit with titration of study drugs during intra-operative period. No significant intergroup difference was observed in Fromme's score during the intra-operative period. The mean total dose of fentanyl (μg/kg) used was found to be significantly lower in group D compared to groups E and N (1.2 ± 0.75 vs. 3.6 ± 1.3 and 2.9 ± 1.1 respectively). The mean heart rate was significantly lower in group D compared to groups E and N at all times of measurement (P < 0.05). The MAP was found to be significantly lower in group D compared to groups E and N after infusion of study drugs, after induction

  7. Nitroglycerine, esmolol and dexmedetomidine for induced hypotension during functional endoscopic sinus surgery: A comparative evaluation

    Directory of Open Access Journals (Sweden)

    Sukhminder Jit Singh Bajwa

    2016-01-01

    Full Text Available Background and Aim: Induced hypotension limits intra-operative blood loss to provide better visibility of the surgical field and diminishes the incidence of major complications during functional endoscopic sinus surgery (FESS. We aimed at comparing nitroglycerine, esmolol and dexmedetomidine for inducing controlled hypotension in patients undergoing FESS. Material and Methods: One hundred and fifty American Society of Anesthesiologists physical status I or II adult patients undergoing FESS under general anesthesia were randomly allocated to three groups of 50 patients each. Group E received esmolol in a loading and maintenance dose of 1 mg/kg over 1 min and 0.5-1.0 mg/kg/h, respectively. Group D received a loading dose of dexmedetomidine 1 μg/kg over 10 min followed by an infusion 0.5-1.0 μg/kg/h, and group N received nitroglycerine infusion at a dose of 0.5-2 μg/kg/min so as to maintain mean arterial pressure (MAP between 60 and 70 mmHg in all the groups. The visibility of the surgical field was assessed by surgeon using Fromme and Boezaart scoring system. Hemodynamic variables, total intra-operative fentanyl consumption, emergence time and time to first analgesic request were recorded. Any side-effects were noted. The postoperative sedation was assessed using Ramsay Sedation Score. Result: The desired MAP (60-70 mmHg could be achieved in all the three study groups albeit with titration of study drugs during intra-operative period. No significant intergroup difference was observed in Fromme′s score during the intra-operative period. The mean total dose of fentanyl (μg/kg used was found to be significantly lower in group D compared to groups E and N (1.2 ± 0.75 vs. 3.6 ± 1.3 and 2.9 ± 1.1 respectively. The mean heart rate was significantly lower in group D compared to groups E and N at all times of measurement (P < 0.05. The MAP was found to be significantly lower in group D compared to groups E and N after infusion of study drugs

  8. Computer-Aided Modeling Framework

    DEFF Research Database (Denmark)

    Fedorova, Marina; Sin, Gürkan; Gani, Rafiqul

    with them. As the required models may be complex and require multiple time and/or length scales, their development and application for product-process design is not trivial. Therefore, a systematic modeling framework can contribute by significantly reducing the time and resources needed for model...... development and application. The proposed work is a part of the project for development of methods and tools that will allow systematic generation, analysis and solution of models for various objectives. It will use the computer-aided modeling framework that is based on a modeling methodology, which combines....... In this contribution, the concept of template-based modeling is presented and application is highlighted for the specific case of catalytic membrane fixed bed models. The modeling template is integrated in a generic computer-aided modeling framework. Furthermore, modeling templates enable the idea of model reuse...

  9. Computer Aided Design of Couplings

    OpenAIRE

    2011-01-01

    The research work explores computer-aided approach to the design of ten different couplings, viza viz: flange, solid rigid, hollow rigid, old ham/ cross-sliding, pin type flexible, sleeve, seller cone/compression, split muff, pulley flange and fairbian’s lap-box couplings. The approach utilizesstandard design equations of these couplings and link them together in computer software todetermine the design parameters of the couplings. The work reviews the procedural stepsinvolved in the design o...

  10. Computer Aided Design of Couplings

    OpenAIRE

    2011-01-01

    The research work explores computer-aided approach to the design of ten different couplings, viz a viz: flange, solid rigid, hollow rigid, old ham/ cross-sliding, pin type flexible, sleeve, seller cone/ compression, split muff, pulley flange and fairbian’s lap-box couplings. The approach utilizes standard design equations of these couplings and link them together in computer software to determine the design parameters of the couplings. The work reviews the procedural steps involved in the des...

  11. Abulia following penetrating brain injury during endoscopic sinus surgery with disruption of the anterior cingulate circuit: Case report

    Directory of Open Access Journals (Sweden)

    Login Ivan S

    2006-01-01

    Full Text Available Abstract Background It is common knowledge that the frontal lobes mediate complex human behavior and that damage to these regions can cause executive dysfunction, apathy, disinhibition and personality changes. However, it is less well known that subcortical structures such as the caudate and thalamus are part of functionally segregated fronto-subcortical circuits, that can also alter behavior after injury. Case presentation We present a 57 year old woman who suffered penetrating brain injury during endoscopic sinus surgery causing right basal ganglia injury which resulted in an abulic syndrome. Conclusion Abulia does not result solely from cortical injury but can occur after disruption anywhere in the anterior cingulate circuit – in the case of our patient, most prominently at the right caudate.

  12. The response to sodium valproate of patients with sinus headaches with normal endoscopic and CT findings.

    Science.gov (United States)

    Dadgarnia, Mohammad Hossein; Atighechi, Saeed; Baradaranfar, Mohammad Hossein

    2010-03-01

    The objectives of this study are to evaluate the patients who have sinus headaches, either self-ascribed or physician-diagnosed, and to determinate the response to sodium valproate in a prophylactic treatment of the patients without positive sino-nasal findings. "Sinus headache" is a patient's complaint or physician-diagnosis that can have a variety of underlying causes. The patients are often treated with multiple courses of antibiotics and occasionally undergo a sinus surgery, often with little or no relief of their symptoms. One hundred and four patients with "sinus headaches" were evaluated prospectively. The patients with a normal rigid nasal endoscopy and a paranasal sinus computed tomography scan were treated with sodium valproate as a prophylactic treatment. After a 3-month follow-up, the patients' response to the treatment was evaluated. Seventy-two patients (69.2%) did not have any positive sino-nasal findings in the nasal endoscopy and the computed tomography scanning. The response rate to the treatment for these patients was as follows: significant improvement in 44 patients (61.1%), partial response (9.7%), no response (15.3%), and ten patients (13.9%) withdrew or failed to follow-up. According to Wilcoxon test, the patients' response rate to sodium valproate was statistically significant (P = 0.001). In conclusion, a majority of "sinus headache" patients do not show any positive sino-nasal pathologic finding. Therefore, we have to consider migraine headache as a considerable cause and sodium valproate as an effective conservative treatment.

  13. Using preoperative unsupervised cluster analysis of chronic rhinosinusitis to inform patient decision and endoscopic sinus surgery outcome.

    Science.gov (United States)

    Adnane, Choaib; Adouly, Taoufik; Khallouk, Amine; Rouadi, Sami; Abada, Redallah; Roubal, Mohamed; Mahtar, Mohamed

    2017-02-01

    The purpose of this study is to use unsupervised cluster methodology to identify phenotype and mucosal eosinophilia endotype subgroups of patients with medical refractory chronic rhinosinusitis (CRS), and evaluate the difference in quality of life (QOL) outcomes after endoscopic sinus surgery (ESS) between these clusters for better surgical case selection. A prospective cohort study included 131 patients with medical refractory CRS who elected ESS. The Sino-Nasal Outcome Test (SNOT-22) was used to evaluate QOL before and 12 months after surgery. Unsupervised two-step clustering method was performed. One hundred and thirteen subjects were retained in this study: 46 patients with CRS without nasal polyps and 67 patients with nasal polyps. Nasal polyps, gender, mucosal eosinophilia profile, and prior sinus surgery were the most discriminating factors in the generated clusters. Three clusters were identified. A significant clinical improvement was observed in all clusters 12 months after surgery with a reduction of SNOT-22 scores. There was a significant difference in QOL outcomes between clusters; cluster 1 had the worst QOL improvement after FESS in comparison with the other clusters 2 and 3. All patients in cluster 1 presented CRSwNP with the highest mucosal eosinophilia endotype. Clustering method is able to classify CRS phenotypes and endotypes with different associated surgical outcomes.

  14. Application of Endoscopic Taking out the Foreign Body in Maxillary Sinus%鼻内镜在取上颌窦异物的临床应用

    Institute of Scientific and Technical Information of China (English)

    庄建谋; 庄文志; 李健祥

    2011-01-01

    Objective: To study the possibility of taking out the foreign body in the maxillary sinus under nasal endoscope.Methods: Eight patients with the foreign bodies in the maxillary sinus were proved by CT, removed part of hook under anesthesia , expanded ostium maxilare and taken out the foreign body.Results: Eight patients with the foreign bodies in the maxillary sinus were taken out by nasal endoscope.Conclusion: Removed foreign bodies in the maxillary sinus under nasal endoscope , the operation is simple, trauma and recovery after the patients rapidly, there are being popularized in clinical otolaryngology.%目的:研究鼻内镜在取上颌窦异物的可行性.方法:对8例经CT证实有上颌窦异物的患者,在全麻下切除部分钩突,开放上颌窦口取出异物.结果:8例上颌窦异物患者经鼻内镜取出.结论:采用鼻内镜下上颌窦异物取出术,手术操作简便,损伤小,术后患者恢复快,有临床推广价值.

  15. Endoscopic Management in Fibrous Dysplasia of Ethmoid Sinus: One Case Report and Literatures Review

    Institute of Scientific and Technical Information of China (English)

    Zhaowei Gu; Zhiwei Cao; Yunxiu Wang

    2009-01-01

    @@ Introduction Fibrous dysplasia(FD)is a sporadic skeletal disorder in which normal bone structures and marrow are replaced by fibro-osseous tissue[1].It is classified into three types:monostotic FD,polyostotic FD,and McCune-Albright syndrome[2].The monostotic iS the most commen form of FD.The disease primarily affects the long bones of the patients,and may also develop in the craniofacial region.However,FD in the paranasal sinuses is uncommon.The case in this report was diagnosed as FD in the ethmoid sinus which is a rarely seen case.

  16. Anatomic variants of interest in endoscopic sinus surgery: role of computed tomography; Variantes anatomicas de interes en cirugia endoscopica nasosinusal. Papel de la tomografia computerizada

    Energy Technology Data Exchange (ETDEWEB)

    Alonso, S.; Arenas, J.; Fernandez, F.; Gil, S.; Guirau, M. D. [Hospital General Universitario de Alicante (Spain)

    2000-07-01

    The detailed radiological study of the anatomy of the nasal cavities and paranasal sinus is essential prior to endoscopic sinus surgery since, on the one hand, it discloses the extent of the disease and, on the other hand, it aids in the detection of the numerous anatomic variants, some of which are of great interest to the endoscopic as the lack of preoperative knowledge of them may increase the risk of complications. the objective of the present report is to review these variants, stressing those that may be associated with a greater surgical risk. Although coronal computed tomography is the technique of choice for pre endoscopy examination, certain structures and anatomic variants are better viewed in axial images. These exceptions include anterior and posterior walls of the frontal sinuses, the anatomic relationships between posterior ethmoid complex and the sphenoid sinus, the relationships between the sphenoid sinus and the optic nerve, and the detection of Onodi cells. Thus, we recommend that the radiological examination include both coronal and axial images. (Author) 16 refs.

  17. Analgesic Effects of Intravenous Acetaminophen vs Placebo for Endoscopic Sinus Surgery and Postoperative Pain: A Randomized Clinical Trial.

    Science.gov (United States)

    Tyler, Matthew A; Lam, Kent; Ashoori, Faramarz; Cai, Chunyan; Kain, Joshua J; Fakhri, Samer; Citardi, Martin J; Cattano, Davide; Luong, Amber

    2017-08-01

    Intravenous acetaminophen is a commonly prescribed analgesic for the prevention and treatment of postsurgical pain. Its efficacy in the context of endoscopic sinus surgery (ESS) has yielded mixed results. To compare the efficacy of perioperative intravenous acetaminophen (IVAPAP) with that of placebo in improving early postoperative pain after endoscopic sinus surgery (ESS). A prospective, randomized clinical trial including 62 patients undergoing ESS for chronic rhinosinusitis in a single tertiary referral hospital. Participants were randomized to receive 1 g of IVAPAP or 100 mL of placebo consisting of saline infusions immediately before the start of surgery and 4 hours after the initial dose. The primary outcome was postoperative pain measured by visual analog scale (VAS) scores up to 24 hours after surgery by blinded observers. Secondary endpoints included postoperative opioid (intravenous and oral) use and adverse events in the 24-hour postoperative period. Of the 62 enrolled adult participants, 60 were randomized (31 to IVAPAP intervention and 29 to placebo). The mean (SD) age of participants was 53.7 (14.7) years and 35 (58%) of the participants were men and 25 (42%) were women. Within the first hour, mean pain scores were reduced in the IVAPAP group compared with the control group, reaching a maximum difference of 7.7 mm on a VAS scale favoring the treatment group with a true difference possibly as high as 22 mm, and the data are compatible with a clinically meaningful difference. At 12- and 24-hours, average pain scores were less in the placebo group and the data are compatible with a clinically meaningful difference of 5.8 (-5.2 to 16.8) and 8.2 (-1.9 to 18.4), respectively, favoring the placebo group. However, at all time points the CIs included the null value and were wide, thus preventing definitive conclusions. Inspection of the secondary outcomes favored IVAPAP, but the wide range of the CIs and inclusion of the null value prevent definitive

  18. Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis

    DEFF Research Database (Denmark)

    Aanaes, K; Rasmussen, N; Pressler, T

    2012-01-01

    of BPI-ANCA may be due to the costimulation of BPI when mounting an immune response against P. aeruginosa. The effect of surgery aiming to eradicate bacteria and infected tissue on BPI-ANCA levels is sparsely described. A cohort of patients with CF were included: 53 patients having extensive image......-guided sinus surgery (EIGSS) with topical postoperative antibiotic treatment, 131 non-operated controls and 36 who had double lung transplantation (LTX). In all 219 patients, serum samples before and after surgery or at similar intervals were analysed for IgG and IgA BPI-ANCA. The EIGSS group showed a highly...

  19. 鼻内镜下蝶窦手术入路及超越蝶窦腔病变的处理%Operation pathways for sphenoidal sinus by nasal endoscope and treatments for correlated diseases beyond scope of sphenoidal sinus

    Institute of Scientific and Technical Information of China (English)

    乐建新; 孔维佳; 张松; 王彦君; 张小萌

    2009-01-01

    目的:探讨蝶窦及鞍区更直接的手术径路,结合影像学资料对超越蝶窦范围的相关疾病进行适当处理,防止严重并发症的发生.方法:在鼻内镜下,分别采用经前筛-后筛-蝶窦、经上鼻道-后筛-蝶窦、经鼻中隔-蝶窦以及直接以后鼻孔上缘为标志经蝶窦前壁自然口进入蝶窦等途径,对46例蝶窦占位并蝶窦骨壁破坏的病变进行处理.结果:蝶窦囊肿及脓囊肿21例,经上鼻道径路处理后痊愈;蝶窦内血肿机化1例,经上鼻道径路清除;蝶窦内血肿并颈内动脉假性动脉瘤3例,1例术中探查发生致命性大出血,后经血管内介入治疗后痊愈,其余2例仅作鼻内镜检查,经DSA证实并行血管内介入治疗后治愈;蝶窦乳头状瘤4例,均行蝶窦自然开口径路,3例治愈,1例因广泛侵犯蝶窦外侧壁仅部分切除;蝶窦胆脂瘤2例,经上鼻道入路完整切除;蝶窦内脑膜脑膨出1例,经蝶窦前壁自然口打开蝶窦,经穿刺抽出脑脊液,手术停止并加固修补暴露脑膜;蝶窦真菌病1例,经上鼻道径路清除蝶窦内病变并联合抗真菌治疗后痊愈;蝶窦恶性肿瘤3例,经前后筛径路切除蝶窦内大部分肿瘤,后辅以放化疗;鼻咽癌侵入蝶窦5例,病理检查证实后行放化疗;垂体瘤术后蝶窦脑脊液鼻漏并肉芽增生5例,经上鼻道或鼻中隔径路均一次修补成功.结论:鼻内镜下处理蝶窦及蝶窦相关疾病径路多样,适当选择径路可达到直接、安全、微创等目的.术前蝶鞍CT薄层扫描、三维重建以及DSA是防止超越蝶窦范围病变手术并发症发生的有效手段之一.%Objective:We probe more direct operation pathways in sphenoidal sinus and saddle area, and take proper measures for correlated diseases which surpass scope of sphenoidal sinus by combining image data, which could prevent serious complication.Method:Under nasal endoscope, the operation approaches we adopted included trans-anterior ethmoid sinus

  20. Quality Indexing with Computer-Aided Lexicography.

    Science.gov (United States)

    Buchan, R. L.

    1992-01-01

    Discussion of computer-aided indexing activity focuses on examples from projects at the National Aeronautics and Space Administration (NASA). Standardization and quality in providing subject access to databases are considered; and computer-aided lexicography, including thesaurus construction, access vocabulary, definitions preparation,…

  1. Computer Aided Design in Engineering Education.

    Science.gov (United States)

    Gobin, R.

    1986-01-01

    Discusses the use of Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) systems in an undergraduate engineering education program. Provides a rationale for CAD/CAM use in the already existing engineering program. Describes the methods used in choosing the systems, some initial results, and warnings for first-time users. (TW)

  2. User-Centered Computer Aided Language Learning

    Science.gov (United States)

    Zaphiris, Panayiotis, Ed.; Zacharia, Giorgos, Ed.

    2006-01-01

    In the field of computer aided language learning (CALL), there is a need for emphasizing the importance of the user. "User-Centered Computer Aided Language Learning" presents methodologies, strategies, and design approaches for building interfaces for a user-centered CALL environment, creating a deeper understanding of the opportunities and…

  3. Computer-aided system design

    Science.gov (United States)

    Walker, Carrie K.

    1991-01-01

    A technique has been developed for combining features of a systems architecture design and assessment tool and a software development tool. This technique reduces simulation development time and expands simulation detail. The Architecture Design and Assessment System (ADAS), developed at the Research Triangle Institute, is a set of computer-assisted engineering tools for the design and analysis of computer systems. The ADAS system is based on directed graph concepts and supports the synthesis and analysis of software algorithms mapped to candidate hardware implementations. Greater simulation detail is provided by the ADAS functional simulator. With the functional simulator, programs written in either Ada or C can be used to provide a detailed description of graph nodes. A Computer-Aided Software Engineering tool developed at the Charles Stark Draper Laboratory (CSDL CASE) automatically generates Ada or C code from engineering block diagram specifications designed with an interactive graphical interface. A technique to use the tools together has been developed, which further automates the design process.

  4. Computer Aided Battery Engineering Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Pesaran, Ahmad

    2016-06-07

    A multi-national lab collaborative team was assembled that includes experts from academia and industry to enhance recently developed Computer-Aided Battery Engineering for Electric Drive Vehicles (CAEBAT)-II battery crush modeling tools and to develop microstructure models for electrode design - both computationally efficient. Task 1. The new Multi-Scale Multi-Domain model framework (GH-MSMD) provides 100x to 1,000x computation speed-up in battery electrochemical/thermal simulation while retaining modularity of particles and electrode-, cell-, and pack-level domains. The increased speed enables direct use of the full model in parameter identification. Task 2. Mechanical-electrochemical-thermal (MECT) models for mechanical abuse simulation were simultaneously coupled, enabling simultaneous modeling of electrochemical reactions during the short circuit, when necessary. The interactions between mechanical failure and battery cell performance were studied, and the flexibility of the model for various batteries structures and loading conditions was improved. Model validation is ongoing to compare with test data from Sandia National Laboratories. The ABDT tool was established in ANSYS. Task 3. Microstructural modeling was conducted to enhance next-generation electrode designs. This 3- year project will validate models for a variety of electrodes, complementing Advanced Battery Research programs. Prototype tools have been developed for electrochemical simulation and geometric reconstruction.

  5. The effect of oral clonidine premedication on blood loss and the quality of the surgical field during endoscopic sinus surgery: a placebo-controlled clinical trial.

    Science.gov (United States)

    Mohseni, Masood; Ebneshahidi, Amin

    2011-08-01

    Bleeding during functional endoscopic sinus surgery (FESS) remains a challenge for both surgeons and anesthesiologists despite several modalities available for improving the surgical field. This study was conducted to evaluate the effect of oral clonidine premedication on blood loss and the quality of the surgical field in FESS. In a placebo-controlled clinical trial, a total of 84 American Society of Anesthesiologists (ASA) physical status I-II patients undergoing endoscopic sinus surgery for chronic sinusitis were randomly allocated to receive either oral clonidine 0.2 mg or identical-looking placebo tablets 90 min before arrival at the operating room. Blood loss in the clonidine group was 214 ± 67 ml on average and that in the placebo group was 276 ± 78 ml (mean ± SD, p clonidine group was significantly lower than that in the placebo group (2 (1-3) vs. 2.5 (2-4), p clonidine group than with that in the placebo group (median score, 4 (3-5) vs. 3 (1-5), p premedication with oral clonidine 0.2 mg can effectively reduce bleeding during FESS.

  6. Open and Endoscopic Management of Fourth Branchial Pouch Sinus - Our Experience.

    Science.gov (United States)

    Arunachalam, Pavai; Vaidyanathan, Venkatraman; Sengottan, Palaninathan

    2015-10-01

    Introduction Acute suppurative neck infections associated with third or fourth branchial arch fistulas are frequently recurrent. Third and fourth branchial arch anomalies are much less common and usually present with recurrent left thyroid lobe abscesses. Objectives The authors present their experience in treating such cases that were observed exclusively in children. Methods The study involved performing a retrospective review of five cases in PSG Institute of Medical Sciences & Research. All cases were evaluated radiologically and with Direct Rigid hypopharyngoscopy. Definitive surgery was performed, including hemithyroidectomy. Results The patients consisted of five children, two boys and three girls. All of them presented with recurrent episodes of neck infection. Investigations performed included computed tomography (CT) fistulography, rigid hypopharyngoscopy and ultrasound, which were useful in preoperatively delineating pyriform sinus fistulous tract. All patients underwent neck exploration with excision of the fistulous tract and hemithyroidectomy. Upon follow-up, all patients are asymptomatic. Conclusions Recurrent neck abscesses in a child should alert the clinician to the possibility of a fourth branchial arch anomaly; therefore, children with this condition require a complete evaluation so the anomaly can be ruled out.

  7. Computer-aided decision support systems for endoscopy in the gastrointestinal tract: a review.

    Science.gov (United States)

    Liedlgruber, Michael; Uhl, Andreas

    2011-01-01

    Today, medical endoscopy is a widely used procedure to inspect the inner cavities of the human body. The advent of endoscopic imaging techniques-allowing the acquisition of images or videos-created the possibility for the development of the whole new branch of computer-aided decision support systems. Such systems aim at helping physicians to identify possibly malignant abnormalities more accurately. At the beginning of this paper, we give a brief introduction to the history of endoscopy, followed by introducing the main types of endoscopes which emerged so far (flexible endoscope, wireless capsule endoscope, and confocal laser endomicroscope). We then give a brief introduction to computer-aided decision support systems specifically targeted at endoscopy in the gastrointestinal tract. Then we present general facts and figures concerning computer-aided decision support systems and summarize work specifically targeted at computer-aided decision support in the gastrointestinal tract. This summary is followed by a discussion of some common issues concerning the approaches reviewed and suggestions of possible ways to resolve them.

  8. Direct navigation on 3D rotational x-ray data acquired with a mobile propeller C-arm: accuracy and application in functional endoscopic sinus surgery.

    Science.gov (United States)

    van de Kraats, Everine B; Carelsen, Bart; Fokkens, Wytske J; Boon, Sjirk N; Noordhoek, Niels; Niessen, Wiro J; van Walsum, Theo

    2005-12-21

    Recently, three-dimensional (3D) rotational x-ray imaging has been combined with navigation technology, enabling direct 3D navigation for minimally invasive image guided interventions. In this study, phantom experiments are used to determine the accuracy of such a navigation set-up for a mobile C-arm with propeller motion. After calibration of the C-arm system, the accuracy is evaluated by pinpointing divots on a special-purpose phantom with known geometry. This evaluation is performed both with and without C-arm motion in between calibration and registration for navigation. The variation caused by each of the individual transformations in the calibration and registration process is also studied. The feasibility of direct navigation on 3D rotational x-ray images for functional endoscopic sinus surgery has been evaluated in a cadaver navigation experiment. Navigation accuracy was approximately 1.0 mm, which is sufficient for functional endoscopic sinus surgery. C-arm motion in between calibration and registration slightly degraded the registration accuracy by approximately 0.3 mm. Standard deviations of each of the transformations were in the range 0.15-0.31 mm. In the cadaver experiment, the navigation images were considered in good correspondence with the endoscopic images by an experienced ENT surgeon. Availability of 3D localization information provided by the navigation system was considered valuable by the ENT surgeon.

  9. Direct navigation on 3D rotational x-ray data acquired with a mobile propeller C-arm: accuracy and application in functional endoscopic sinus surgery

    Science.gov (United States)

    van de Kraats, Everine B.; Carelsen, Bart; Fokkens, Wytske J.; Boon, Sjirk N.; Noordhoek, Niels; Niessen, Wiro J.; van Walsum, Theo

    2005-12-01

    Recently, three-dimensional (3D) rotational x-ray imaging has been combined with navigation technology, enabling direct 3D navigation for minimally invasive image guided interventions. In this study, phantom experiments are used to determine the accuracy of such a navigation set-up for a mobile C-arm with propeller motion. After calibration of the C-arm system, the accuracy is evaluated by pinpointing divots on a special-purpose phantom with known geometry. This evaluation is performed both with and without C-arm motion in between calibration and registration for navigation. The variation caused by each of the individual transformations in the calibration and registration process is also studied. The feasibility of direct navigation on 3D rotational x-ray images for functional endoscopic sinus surgery has been evaluated in a cadaver navigation experiment. Navigation accuracy was approximately 1.0 mm, which is sufficient for functional endoscopic sinus surgery. C-arm motion in between calibration and registration slightly degraded the registration accuracy by approximately 0.3 mm. Standard deviations of each of the transformations were in the range 0.15-0.31 mm. In the cadaver experiment, the navigation images were considered in good correspondence with the endoscopic images by an experienced ENT surgeon. Availability of 3D localization information provided by the navigation system was considered valuable by the ENT surgeon.

  10. Direct navigation on 3D rotational x-ray data acquired with a mobile propeller C-arm: accuracy and application in functional endoscopic sinus surgery

    Energy Technology Data Exchange (ETDEWEB)

    Kraats, Everine B van de [Image Sciences Institute, University Medical Center Utrecht (Netherlands); Carelsen, Bart [Academic Medical Center Amsterdam, Medical Physics Department (Netherlands); Fokkens, Wytske J [Academic Medical Center Amsterdam, Department of Otorhinolaryngology (Netherlands); Boon, Sjirk N [Philips Medical Systems, Best (Netherlands); Noordhoek, Niels [Philips Medical Systems, Best (Netherlands); Niessen, Wiro J [Image Sciences Institute, University Medical Center Utrecht (Netherlands); Walsum, Theo van [Image Sciences Institute, University Medical Center Utrecht (Netherlands)

    2005-12-21

    Recently, three-dimensional (3D) rotational x-ray imaging has been combined with navigation technology, enabling direct 3D navigation for minimally invasive image guided interventions. In this study, phantom experiments are used to determine the accuracy of such a navigation set-up for a mobile C-arm with propeller motion. After calibration of the C-arm system, the accuracy is evaluated by pinpointing divots on a special-purpose phantom with known geometry. This evaluation is performed both with and without C-arm motion in between calibration and registration for navigation. The variation caused by each of the individual transformations in the calibration and registration process is also studied. The feasibility of direct navigation on 3D rotational x-ray images for functional endoscopic sinus surgery has been evaluated in a cadaver navigation experiment. Navigation accuracy was approximately 1.0 mm, which is sufficient for functional endoscopic sinus surgery. C-arm motion in between calibration and registration slightly degraded the registration accuracy by approximately 0.3 mm. Standard deviations of each of the transformations were in the range 0.15-0.31 mm. In the cadaver experiment, the navigation images were considered in good correspondence with the endoscopic images by an experienced ENT surgeon. Availability of 3D localization information provided by the navigation system was considered valuable by the ENT surgeon.

  11. Safety analysis of long-term budesonide nasal irrigations in patients with chronic rhinosinusitis post endoscopic sinus surgery.

    Science.gov (United States)

    Soudry, Ethan; Wang, Jane; Vaezeafshar, Reza; Katznelson, Laurence; Hwang, Peter H

    2016-06-01

    Although the safety of topical nasal steroids is well established for nasal spray forms, data regarding the safety of steroid irrigations is limited. We studied the effect of long-term budesonide nasal irrigations (>6 months) on hypothalamic-pituitary-adrenal axis (HPAA) function and intraocular pressure (IOP) in patients post-endoscopic sinus surgery. This was retrospective case series. Adrenal function was assessed by using the high-dose cosyntropin stimulation test. A total of 48 patients were assessed, with a mean duration of budesonide irrigations of 22 months. Stimulated cortisol levels were abnormally low in 11 patients (23%). None reported to have symptoms of adrenal suppression. Three of 4 patients who repeated the study being off budesonide for at least 1 month returned to near normal levels. Logistic regression analysis revealed that concomitant use of both nasal steroid sprays and pulmonary steroid inhalers was significantly associated with HPAA suppression (p = 0.024). Patients with low stimulated cortisol levels were able to continue budesonide irrigations under the supervision of an endocrinologist without frank clinical manifestations of adrenal insufficiency. IOP was within normal limits in all patients. Long-term use of budesonide nasal irrigations is generally safe, but asymptomatic HPAA suppression may occur in selected patients. Concomitant use of both nasal steroid sprays and pulmonary steroid inhalers while using daily budesonide nasal irrigations is associated with an increased risk. Rhinologists should be alerted to the potential risks of long-term use of budesonide nasal irrigations, and monitoring for HPAA suppression may be warranted in patients receiving long-term budesonide irrigation therapy. © 2016 ARS-AAOA, LLC.

  12. Clinical Observation on Treatment of 65 Cases of Chronic Sinusitis and Nasal Polyps with Endoscopic Sinus Surgery Combined with Chinese Medicine%鼻内窥镜鼻窦手术配合中药治疗慢性鼻窦炎鼻息肉

    Institute of Scientific and Technical Information of China (English)

    沙海滨

    2009-01-01

    目的 观察鼻内窥镜鼻窦手术配合中药治疗慢性鼻窦炎、鼻息肉的临床疗效.方法 将63例慢性鼻窦炎、鼻息肉患者随机分为两组,对照组32例给予鼻内窥镜鼻窦手术治疗,治疗组33例采用鼻内窥镜鼻窦手术配合中药治疗.结果 治疗组总有效率为90.9%,对照组总有效率为75.0%,两组总有效率比较,差异有统计学意义(p=0.0416,P<0.05).结论 采用鼻内窥镜鼻窦手术配合中药对慢性鼻窦炎、鼻息肉有疗.%Objective To observe clinical effect of treating chronic sinusitis and nasal polyps with endoscopic sinus surgery combined with Chinese medicine. Methods 65 patients with chronic sinusitis and nasal polyps were randomly divided into a control group and a treatment group. The control group was treated with endoscopic sinus surgery only, and the treatment group was treated with endoscopic sinus surgery combined with Chinese medicine. Results The total effective rate in the treatment group and the control group was 90.9% and 75.0%, respectively. There was a significant dieffference between two groups (P= 0.0416, P<0.05 ). Conclusion The treatment of endoscopic sinus surgery combined with Chinese medicine on chronic sinusitis and nasal polyps is better than endoscopic sinus surgery only.

  13. Tratamento endoscópico do cisto odontogênico com extensão intra-sinusal Endoscopic treatment of odontogenic cyst with intra-sinusal extension

    Directory of Open Access Journals (Sweden)

    Antonio C. Cedin

    2005-06-01

    Full Text Available Cistos odontogênicos são lesões pouco comuns que podem ocorrer após inflamação da polpa dentária. A abordagem terapêutica destes cistos é realizada em consultórios odontológicos e, dependendo de sua extensão, pode ocasionar a formação de fístula oroantral e rinossinusite crônica. O objetivo deste trabalho é propor o tratamento videoendoscópico do cisto odontogênico com expressão em seio maxilar. Realizou-se um estudo retrospectivo de quatro casos de cistos de origem dentária, com extensão intra-sinusal, complicados com fístula oroantral e sinusite crônica de seio maxilar após curetagem em consultório odontológico. Utilizamos a técnica videoendoscópica via transmaxilar para acessarmos o cisto intra-sinusal. Os quatro pacientes apresentaram resolução do quadro infeccioso e cicatrização da fístula oroantral, sem recidiva durante o seguimento. A cirurgia videoendoscópica é um método seguro e efetivo para tratamento do cisto odontogênico descrito, podendo contribuir para prevenir a formação de fístula oroantral e supuração de seio maxilar.Odontogenic cyst is a common lesion that can happen after inflammation of the dental pulp. The therapeutic approach of these cysts is made at dentist's offices, and depending on their extension, they may develop oroantral fistula and chronic sinusitis. The objective of this study is to propose the videoendoscopic treatment of the odontogenic cyst with expression in the maxillary sinus. We made a retrospective study of four cases of cysts of dental origin, with intra-sinusal extension, complicated with oroantral fistula and chronic sinusitis of maxillary sinus after curettage in a dentist's office. We used the videoendoscopic technique through transmaxillary approach to access the intra-sinusal cyst. All the four patients presented resolution of the infectious manifestation and healing of the oroantral fistula, without recurrence within two years of follow

  14. Clinical Efficacy of Endoscopic Sinus Surgery for Fungal Sinusitis%鼻窦内窥镜手术治疗真菌性鼻窦炎的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    韩宇峰

    2015-01-01

    目的:探究临床上使用鼻窦内窥镜用于真菌性的鼻窦炎(NIFS)的手术治疗的疗效。方法随机选取我院2012年3月~2015年3月份的80例 NIFS 患者,对其临床的病症以及体征进行回顾性的调查分析。将患者在局部麻醉的条件下采用 Messerklinger 方式进行鼻内镜手术。结果本研究中的80例患者,最终都康复出院。对其进行定期随访,随访时间在0.5~3年。随访过程中,发现患者的鼻道以及上颌窦口很通畅,鼻黏膜正常,在患者的鼻窦中大部分没有发现真菌性质的块状物质,也没有异常的鼻腔分泌物;有2例患者复发再次入院治疗后康复。复发率为2.5%。结论对患者使用 CT 检查,然后行鼻窦内窥镜的手术疗法,有利于对患者的鼻窦炎做出准确的诊断,但临床上的确诊还需借助病理学的进一步检查;对于 NIFS 的治疗,采取鼻内窥镜的手术疗法是首选。%Objective To explore the clinical use of endoscopic sinus for fungal sinusitis (NIFS) the efficacy of surgical treatment. Methods In March 2012 to March 2015, 80 cases of patients NIFS were randomly selected in our hospital, the investigation analyzed retrospectively the clinical signs of the disease as well. The patient under local anesthesia in surgery, the use of endoscopic surgery Messerklinger way. Results In this study, 80 patients were eventually discharged. Its regular follow-up, follow-up time of 0.5 to 3 years. During follow-up, patients with maxillary sinus and nasal passages are clear, 2 patients relapse rehabilitation after hospitalization. The recurrence rate was 2.5%. Conclusion NIFS patients for CT examination, then underwent endoscopic sinus surgery therapy is beneficial for patients with sinusitis make an accurate diagnosis, but the diagnosis of clinical pathology needs further examination of the aid, for NIFS treatment, take endoscopic sinus surgery is the preferred treatment.

  15. Transnasal endoscopic anatomy and approaches to the cavernous sinus%海绵窦的内镜解剖以及手术入路

    Institute of Scientific and Technical Information of China (English)

    刘剑锋; 曲秋懿; 杨大章; 韩军; 张秋航; Carl H.Snyderman; Juan C.Fernandez-Miranda; Paul A.Gardner

    2013-01-01

    目的 探讨内镜下海绵窦的解剖特点以及手术入路.方法 6例(12侧)新鲜尸头,有色硅胶灌注血管.行内镜经鼻-蝶入路和经筛-翼-蝶入路,完成蝶窦开放,蝶窦后壁切除,翼突部分切除和蝶窦外侧壁切除.充分暴露海绵窦及其周围结构.应用Stroz Image l高清系统采集图像.结果 颈内动脉海绵窦段穿行海绵窦将海绵窦分为5个部分,即内侧海绵窦、外侧海绵窦、海绵窦后上腔隙、海绵窦后下腔隙和海绵窦前下腔隙.海绵窦段颈内动脉的分支包括:脑膜垂体干、McConnell包膜动脉和下外侧干.颅神经Ⅲ、Ⅳ走行于海绵窦外侧壁的上部;颅神经Ⅴ1自Meckel腔向眶上裂斜行;颅神经Ⅵ自海绵窦后下腔隙底部从颈内动脉后膝部的内侧绕行到外侧,穿过海绵窦窦腔,向外上前至眶上裂.内镜经鼻海绵窦手术入路分为经蝶-鞍-内侧海绵窦入路(颈内动脉内侧入路)和经筛-翼-蝶-外侧海绵窦入路(颈内动脉外侧入路).前者可以暴露海绵窦段颈内动脉的内侧部,部分海绵窦后上、后下腔隙.后者可以暴露海绵窦前下腔隙、外侧海绵窦以及外侧壁的颅神经.结论 海绵窦的解剖非常复杂,颈内动脉以及颅神经Ⅲ、Ⅳ、Ⅴ1、Ⅵ穿行其内,与周同重要静脉窦相交通.熟悉掌握内镜下海绵窦解剖以及手术入路对于内镜下处理海绵窦以及海绵窦相关的病变有重要意义.%Objective The goal of the current study is to describe the transnasal endoscopic anatomy of the cavernous sinus and to provide the surgical approaches to this area.Methods Six siliconinjected adult cadaveric heads (12 sides) were dissected through endoscopic endonasal approach.The cavernous sinus and adjacent structures were exposed; detailed anatomies were demonstrated.High-quality pictures were produced.Results The cavernous sinus had four walls,namely medial,lateral,posterior and superior walls.Five venous spaces within the sinus

  16. Comparison of surgical conditions following premedication with oral clonidine versus oral diazepam for endoscopic sinus surgery: A randomized, double-blinded study

    Directory of Open Access Journals (Sweden)

    Rohini V Bhat Pai

    2016-01-01

    Full Text Available Background and Aims: Endoscopic sinus surgery (ESS provides a challenge and an opportunity to the anesthesiologists to prove their mettle and give the surgeons a surgical field which can make their delicate surgery safer,more precise and faster. The aim of the study was to evaluate the surgical field and the rate of blood loss in patients premedicated with oral clonidine versus oral diazepam for endoscopic sinus surgery. Material and Methods: ASA I or II patients who were scheduled to undergo ESS were randomly allocated to group D (n = 30 or group C (n = 30. The patients′ vital parameters, propofol infusion rate, and rate of blood loss were observed and calculated. The surgeon, who was blinded, rated the visibility of the surgical field from grade 0-5. Results: In the clonidine group, the rate of blood loss, the surgical time, propofol infusion rate was found to be statistically lower as compared to the diazepam group. Also a higher number of patients in the clonidine group had a better surgical score (better surgical field than the diazepam group and vice versa. Conclusions: Premedication with clonidine as compared to diazepam, provides a better surgical field with less blood loss in patients undergoing ESS.

  17. Comparison of surgical conditions following premedication with oral clonidine versus oral diazepam for endoscopic sinus surgery: A randomized, double-blinded study

    Science.gov (United States)

    Bhat Pai, Rohini V; Badiger, Santhoshi; Sachidananda, Roopa; Basappaji, Santhosh Mysore Chandramouli; Shanbhag, Raghunath; Rao, Raghavendra

    2016-01-01

    Background and Aims: Endoscopic sinus surgery (ESS) provides a challenge and an opportunity to the anesthesiologists to prove their mettle and give the surgeons a surgical field which can make their delicate surgery safer,more precise and faster. The aim of the study was to evaluate the surgical field and the rate of blood loss in patients premedicated with oral clonidine versus oral diazepam for endoscopic sinus surgery. Material and Methods: ASA I or II patients who were scheduled to undergo ESS were randomly allocated to group D (n = 30) or group C (n = 30). The patients' vital parameters, propofol infusion rate, and rate of blood loss were observed and calculated. The surgeon, who was blinded, rated the visibility of the surgical field from grade 0-5. Results: In the clonidine group, the rate of blood loss, the surgical time, propofol infusion rate was found to be statistically lower as compared to the diazepam group. Also a higher number of patients in the clonidine group had a better surgical score (better surgical field) than the diazepam group and vice versa. Conclusions: Premedication with clonidine as compared to diazepam, provides a better surgical field with less blood loss in patients undergoing ESS. PMID:27275059

  18. Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospective, randomised, controlled single-blinded trial.

    Science.gov (United States)

    Park, D-Y; Chung, H J; Sim, N S; Jo, K H; Kim, D H; Kim, C-H; Yoon, J-H

    2016-06-01

    Calcium alginate is a biodegradable gel-transforming agent widely used for nasal packing. It can reduce pain and improve comfort. However, few randomised controlled trials have compared the efficacy of calcium alginate nasal packing with that of other biodegradable gel-transforming materials. Prospective, randomised, single-blinded controlled study. Yonsei University Severance Hospital, a tertiary academic medical centre. Twenty-seven patients (54 nostrils) with chronic rhinosinusitis who were scheduled for bilateral endoscopic sinus surgery were enrolled. After surgery, one nostril was packed with calcium alginate and the other with carboxymethyl cellulose. Only patients with an intersinus chronic rhinosinusitis severity score difference of ≤1 were included. Visual analogue scale (VAS) scores for postoperative pain, discomfort from nasal discharge and pain during packing removal were analysed. Two independent rhinologists who were blinded to the assessments separately scored adhesions, oedema and infection by endoscopic digital photography at 1, 4 and 8 weeks postoperatively. There were no significant differences in VAS scores for postoperative pain, discomfort from nasal discharge or pain during packing removal between calcium alginate packings and carboxymethyl cellulose packings. Inter-rater variability of adhesion, oedema and infection scores was acceptable. Adhesion severity and oedema scores at 4 weeks were significantly lower with calcium alginate packing than with carboxymethyl cellulose. Infection severity scores also tended to be lower with calcium alginate than with carboxymethyl cellulose, but the difference was not significant. Calcium alginate nasal packing is associated with reduced severity of oedema and adhesions after endoscopic sinus surgery. © 2015 John Wiley & Sons Ltd.

  19. Computer Aided Drug Design: Success and Limitations.

    Science.gov (United States)

    Baig, Mohammad Hassan; Ahmad, Khurshid; Roy, Sudeep; Ashraf, Jalaluddin Mohammad; Adil, Mohd; Siddiqui, Mohammad Haris; Khan, Saif; Kamal, Mohammad Amjad; Provazník, Ivo; Choi, Inho

    2016-01-01

    Over the last few decades, computer-aided drug design has emerged as a powerful technique playing a crucial role in the development of new drug molecules. Structure-based drug design and ligand-based drug design are two methods commonly used in computer-aided drug design. In this article, we discuss the theory behind both methods, as well as their successful applications and limitations. To accomplish this, we reviewed structure based and ligand based virtual screening processes. Molecular dynamics simulation, which has become one of the most influential tool for prediction of the conformation of small molecules and changes in their conformation within the biological target, has also been taken into account. Finally, we discuss the principles and concepts of molecular docking, pharmacophores and other methods used in computer-aided drug design.

  20. Computer-Aided Modelling Methods and Tools

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    The development of models for a range of applications requires methods and tools. In many cases a reference model is required that allows the generation of application specific models that are fit for purpose. There are a range of computer aided modelling tools available that help to define...... a taxonomy of aspects around conservation, constraints and constitutive relations. Aspects of the ICAS-MoT toolbox are given to illustrate the functionality of a computer aided modelling tool, which incorporates an interface to MS Excel....

  1. Computer Aided Modelling – Opportunities and Challenges

    DEFF Research Database (Denmark)

    2011-01-01

    This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model-based solu......This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model...

  2. Acesso endoscópico para tratamento de mucoceles fronto-etmoidais Endoscopic endonasal approach for fronto-ethmoidal sinus mucoceles

    Directory of Open Access Journals (Sweden)

    Rodrigo P. Santos

    2002-05-01

    Full Text Available Introdução: A mucocele, lesão benigna expansiva decorrente do acúmulo de secreção em cavidade fechada, é uma afecção rara em otorrinolaringologia, acometendo principalmente os seios frontal e etmoidal. Podemos dividir a etiologia em forma obstrutiva e inflamatória. Objetivo: Avaliar a eficácia do tratamento cirúrgico para mucoceles fronto-etmoidais pela técnica endoscópica isolada. Forma de estudo: Clínico prospectivo. Material e método: Foram estudadas a apresentação clínica, evolução e resultado de 13 casos de mucoceles durante o período de janeiro de 2000 a abril de 2001. Resultado: Dos pacientes tratados, 7 tinham como etiologia a forma inflamatória e 2 a forma obstrutiva, todos apresentando proptose como queixa principal. Dois pacientes apresentaram complicações oftalmológicas, sendo necessária concomitante a marsupialização endoscópica, a descompressão de órbita. Nenhum paciente apresentou recidiva após acompanhamento que variou de 7 a 22 meses. Conclusão: A via endoscópica é efetiva no tratamento cirúrgico das mucoceles e evita complicações das técnicas usadas anteriormente.Introduction: The mucocele is an expansive benign tumor due to the filling of a closed cavity with mucus. Frequently involving the fronto-ethmoidal sinus, it is a rare otolaryngological condition. The etiology is divided into inflammatory and obstructive causes. Aim: To evaluate the endoscopic endonasal surgical approach for fronto-ethmoidal sinus mucoceles. Study design: Clinical prospective. Material and method: Thirteen patients were followed during the period of January of 2000 to April of 2001, regarding the clinical findings, evolution and surgical results. Results: All patients presented proptosis as the major symptom. Seven patients had the inflammatory form and two the obstructive one. Two patients presented ophthalmologic complications and underwent orbital decompression associated with the endoscopic endonasal

  3. Development of a new endoscope holder for head and neck surgery--from the technical design concept to implementation.

    Science.gov (United States)

    Kristin, Julia; Kolmer, Armin; Kraus, Peter; Geiger, Robert; Klenzner, Thomas

    2015-05-01

    Endoscope holders are utilized by a variety of surgeons but are not commonplace in head and neck surgery. The SOLOASSIST active camera holder, which is currently used for abdominal surgery, will soon be adapted for head and neck surgery in collaboration with AKTORmed GmbH SOLO SURGERY (Barbing, Germany). In our pre-feasibility study, we analyzed the use of the existing endoscope holder on anatomical specimens during head and neck surgery. Based on these results, we are proceeding towards the development of a new endoscope holder for head and neck surgery. First, we drafted the technical concepts and discussed the advantages and disadvantages of the system. Then, we used anatomic specimens to measure the forces that occur intraoperatively during sinus surgery. Next, we designed a computer-aided design (CAD) model. Finally, we developed the first production prototype and used it for a frontal skull base procedure on an anatomical specimen. We present the three most promising concepts for a new holder. The resulting total force (F res = √(X (2) + Y (2) + Z (2))) was calculated to be 3.2 N during sinus surgery. We could observe all necessary intraoperative landmarks with the endoscope and its holder in a sinus and frontal skull base surgery. We developed a production prototype of a new endoscope holder and demonstrate satisfactory results in the use of anatomic specimens for skull base surgery.

  4. The clinical effect of Maxillary sinus fistula neoplasty assisted with endoscopic%鼻内镜辅助下口腔上颌窦瘘修补术的临床疗效

    Institute of Scientific and Technical Information of China (English)

    顾晓莉

    2015-01-01

    目的:探讨口腔上颌窦瘘的修补方法。方法:对5例合并严重上颌窦炎的口腔上颌窦瘘患者,在鼻内镜辅助下采用口腔合瓣缝合加上颌窦内“三明治”法修补。结果:5例患者均一期愈合,随访3个月~1年,瘘口愈合良好,复查鼻窦CT上颌窦炎症消失。结论:鼻内镜辅助下口腔内合瓣缝合加上颌窦内“三明治”法修补术是治疗合并严重上颌窦炎口腔上颌窦瘘的有效方法。%Objective:To investigate the repair method of maxillary sinus fistula.Methods:5 patients with oral maxillary sinus fistula combined severe maxillary sinusitis were taken oral sympetalous suture plus maxillary sinus "sandwich" repair under endoscopic assisted.Results:All of those 5 patients were primary healing,and followed up for 3 months to 1 years,the fistula of patients healing well,and the inflammation of maxillary sinus disappeared when reviewed the sinus CT.Conclusion:Oral sympetalous suture plus maxillary sinus "sandwich" repair under endoscopic assisted is an effective treatment of patients with oral maxillary sinus fistula combined severe maxillary sinusitis.

  5. Packing material on outcomes of sinus mucosa with chronic rhinosinusitis after endoscopic sinus surgery%鼻内镜术后不同填塞材料对术后黏膜转归的影响

    Institute of Scientific and Technical Information of China (English)

    许海波; 洪燕丽; 李兆生; 许振跃

    2016-01-01

    Objective To explore the effect of different packing materials on sinus mucosa with chronic rhinosinusitis after endoscopic sinus surgery.Methods A total of 167 patients with chronic rhinosinusitis were divided into the frag-mentable nasal dressing group A(n =93)and the swell sponge group B(n =74).Using Lund-Mackay CT scoring sys-tem,visual analogue scales(VAS)and Lund-Kennedy endoscopic scoring system,all patients were assessed in recover in pre-operation period,and the second week,the fourth week,and the twelfth week after the surgery.The data were analyzed by SPSS18.0 statistics software to compare the differences of outcomes of sinus mucosa .Results There was no difference about Lund-Mackay CT scores,the VAS scores and Lund-Kennedy endoscopic scores in two groups be-fore surgery(P >0.05).About Lund-Kennedy endoscopic scoring,the scores of the two groups presented significant difference(P <0.01).Comparing with the scores of the second week,the scores of group A of the fourth week,and the twelfth week were lower than those of the group B (P <0.01).The VAS scores of group A were all significantly different from those of group B at same period(P <0.01),and the scores of group A at the post-operative 4 and 12 week were lower than those of group B.5 cases of group A and 7 cases of group B had sinus region oedema seriously, ves hyperplasy and polypus recurrence.After individualized treatment,sinus mucosa presented recovery tendency. Conclusion Applying of fragmentable nasal dressing can promote preferable outcomes of sinus mucosa with chronic rhinosinusitis after endoscopic sinus surgery.%目的:探讨鼻内镜手术后,鼻腔不同填塞材料对慢性鼻窦炎患者鼻窦术腔黏膜转归的影响。方法对入选的167例鼻窦炎患者按填塞材料的不同分为纳吸棉组(A 组,n =93)和膨胀海绵组(B 组,n =74)。两组患者均执行同样的入院前治疗,由同一高年资医师手术,并给予相同的术后用药及复查

  6. Computer-Aided Medical Diagnosis. Literature Review

    Science.gov (United States)

    1978-12-15

    BOUCKAERT, A., Computer-aided diagnosis of goitres in a cancer department, Int. J. Bio-’Med. Comput., 3 (1972) p. 3. BOYLE, J. A., GREIG, W. R., FRANKLIN, D...toxic goitre , Q. J. Med., 35 (1966) p. 565. Bricetti, A. B. and Bleich, H. L., A computer program that evaluates patients with hypercalcemia, J

  7. Computer-Aided Corrosion Program Management

    Science.gov (United States)

    MacDowell, Louis

    2010-01-01

    This viewgraph presentation reviews Computer-Aided Corrosion Program Management at John F. Kennedy Space Center. The contents include: 1) Corrosion at the Kennedy Space Center (KSC); 2) Requirements and Objectives; 3) Program Description, Background and History; 4) Approach and Implementation; 5) Challenges; 6) Lessons Learned; 7) Successes and Benefits; and 8) Summary and Conclusions.

  8. Computer Aided Learning of Mathematics: Software Evaluation

    Science.gov (United States)

    Yushau, B.; Bokhari, M. A.; Wessels, D. C. J.

    2004-01-01

    Computer Aided Learning of Mathematics (CALM) has been in use for some time in the Prep-Year Mathematics Program at King Fahd University of Petroleum & Minerals. Different kinds of software (both locally designed and imported) have been used in the quest of optimizing the recitation/problem session hour of the mathematics classes. This paper…

  9. Computer Aided Continuous Time Stochastic Process Modelling

    DEFF Research Database (Denmark)

    Kristensen, N.R.; Madsen, Henrik; Jørgensen, Sten Bay

    2001-01-01

    A grey-box approach to process modelling that combines deterministic and stochastic modelling is advocated for identification of models for model-based control of batch and semi-batch processes. A computer-aided tool designed for supporting decision-making within the corresponding modelling cycle...

  10. Computer aided pantograph design for garment panels

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Discusses the difficulties and problems with manual pantograph ofgarment panels, introduces several typical pantographic ways and their characteristics both at home and abroad, presents a new pantographic method based on similar figures developed to overcome the deficiency of those methods, so as to realize computer aid automatic panel pantograph.

  11. Computer Aided Control System Design (CACSD)

    Science.gov (United States)

    Stoner, Frank T.

    1993-01-01

    The design of modern aerospace systems relies on the efficient utilization of computational resources and the availability of computational tools to provide accurate system modeling. This research focuses on the development of a computer aided control system design application which provides a full range of stability analysis and control design capabilities for aerospace vehicles.

  12. Computer-aided design–computer-aided engineering associative feature-based heterogeneous object modeling

    Directory of Open Access Journals (Sweden)

    Jikai Liu

    2015-12-01

    Full Text Available Conventionally, heterogeneous object modeling methods paid limited attention to the concurrent modeling of geometry design and material composition distribution. Procedural method was normally employed to generate the geometry first and then determine the heterogeneous material distribution, which ignores the mutual influence. Additionally, limited capability has been established about irregular material composition distribution modeling with strong local discontinuities. This article overcomes these limitations by developing the computer-aided design–computer-aided engineering associative feature-based heterogeneous object modeling method. Level set functions are applied to model the geometry within computer-aided design module, which enables complex geometry modeling. Finite element mesh is applied to store the local material compositions within computer-aided engineering module, which allows any local discontinuities. Then, the associative feature concept builds the correspondence relationship between these modules. Additionally, the level set geometry and material optimization method are developed to concurrently generate the geometry and material information which fills the contents of the computer-aided design–computer-aided engineering associative feature model. Micro-geometry is investigated as well, instead of only the local material composition. A few cases are studied to prove the effectiveness of this new heterogeneous object modeling method.

  13. Rendering-based video-CT registration with physical constraints for image-guided endoscopic sinus surgery

    Science.gov (United States)

    Otake, Y.; Leonard, S.; Reiter, A.; Rajan, P.; Siewerdsen, J. H.; Ishii, M.; Taylor, R. H.; Hager, G. D.

    2015-03-01

    We present a system for registering the coordinate frame of an endoscope to pre- or intra- operatively acquired CT data based on optimizing the similarity metric between an endoscopic image and an image predicted via rendering of CT. Our method is robust and semi-automatic because it takes account of physical constraints, specifically, collisions between the endoscope and the anatomy, to initialize and constrain the search. The proposed optimization method is based on a stochastic optimization algorithm that evaluates a large number of similarity metric functions in parallel on a graphics processing unit. Images from a cadaver and a patient were used for evaluation. The registration error was 0.83 mm and 1.97 mm for cadaver and patient images respectively. The average registration time for 60 trials was 4.4 seconds. The patient study demonstrated robustness of the proposed algorithm against a moderate anatomical deformation.

  14. Creating illusion in computer aided performance

    OpenAIRE

    Marshall, Joe

    2009-01-01

    This thesis studies the creation of illusion in computer aided performance. Illusion is created here by using deceptions, and a design framework is presented which suggests several different deception strategies which may be useful. The framework has been developed in an iterative process in tandem with the development of 3 real world performances which were used to explore deception strategies. The first case study presents a system for augmenting juggling performance. The techniques tha...

  15. Computer-Aided Pneumatic Circuit Design

    OpenAIRE

    TEKİNER, Zafer; KORKUT, İhsan

    2001-01-01

    In this study, a user-interactive computer program was developed for computer-aided pneumatic circuit design. The pneumatic circuit elements were selected and designed by the determination of the main principles that are in accordance with the aim the user is going to specify. A database was established by forming IGES files for pneumatic circuit elements. In addition to this database, lists displaying the connection nodes of each element were prepared. The coordinates will be conne...

  16. Genetic algorithms in computer aided inductor design

    OpenAIRE

    Jean Fivaz; Willem A. Cronjé

    2004-01-01

    The goal of this investigation is to determine the advantages of using genetic algorithms in computer-aided design as applied to inductors.  These advantages are exploited in design problems with a number of specifications and constraints, as encountered in power electronics during practical inductor design. The design tool should be able to select components, such as cores and wires, from databases of available components, and evaluate these choices based on the components’ characteristic d...

  17. Computer-aided dispatching system design specification

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, M.G.

    1997-12-16

    This document defines the performance requirements for a graphic display dispatching system to support Hanford Patrol Operations Center. This document reflects the as-built requirements for the system that was delivered by GTE Northwest, Inc. This system provided a commercial off-the-shelf computer-aided dispatching system and alarm monitoring system currently in operations at the Hanford Patrol Operations Center, Building 2721E. This system also provides alarm back-up capability for the Plutonium Finishing Plant (PFP).

  18. The silent sinus syndrome.

    Science.gov (United States)

    Monos, Tova; Levy, Jaime; Lifshitz, Tova; Puterman, Moshe

    2005-05-01

    Patients with silent sinus syndrome typically present for investigation of facial asymmetry. Unilateral, spontaneous enophthalmos and hypoglobus are the prominent findings at examination. Imaging of the orbit and sinuses characteristically show unilateral maxillary sinus opacification and collapse with inferior bowing of the orbital floor. It has been suggested that SSS is due to hypoventilation of the maxillary sinus secondary to ostial obstruction and sinus atelectasis with chronic negative pressure within the sinus. Treatment involves functional endoscopic sinus surgery for reestablishing a functional drainage passage, and a reconstructive procedure of the floor of the orbit for repairing the hypoglobus and cosmetic deformity. Ophthalmologists, otorhinolaryngologists, and radiologists must be familiarized with this relatively newly reported disease.

  19. Recurrent pyriform sinus fistula successfully treated by endoscopic Glubran 2 sealing: A rare case and literature review

    Science.gov (United States)

    Di Nardo, Giovanni; Valentini, Valentino; Angeletti, Diletta; Frediani, Simone; Iannella, Giannicola; Cozzi, Denis; Roggini, Mario; Magliulo, Giuseppe

    2016-01-01

    Objectives: The authors present the case of a 3-year-old girl with a history of complicated surgery for removing a third branchial cleft fistula. Methods: An endoscopic approach using N-butyl-2-acrylate and metacrilosisolfolane glue (GLUBRAN 2) to seal the fistula was performed. Results: The clinical and radiological 6-year follow-up confirmed the absence of the fistulous orifice and the persistence of scar due to previous open-neck surgical procedures. Conclusion: endoscopic Glubran 2 sealing has been an effective treatment procedure for branchial fistula. PMID:27781098

  20. Ectopic ACTH-secreting pituitary adenoma of the sphenoid sinus: case report of endoscopic endonasal resection and systematic review of the literature.

    Science.gov (United States)

    Seltzer, Justin; Lucas, Joshua; Commins, Deborah; Lerner, Olga; Lerner, Alexander; Carmichael, John D; Zada, Gabriel

    2015-02-01

    Ectopic pituitary adenomas are exceedingly rare entities that are often misdiagnosed. The resulting delay in diagnosis may be particularly concerning in the case of Cushing syndrome caused by an ectopic adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma. Although the total resection of ectopic adenomas results in rapid and durable remission, persistent Cushing syndrome is often associated with permanently damaging invasive procedures and significantly higher risk of mortality. The authors report the case of a 48-year-old man with ACTH-dependent Cushing syndrome. On the morning before surgery, his serum cortisol measured 51 μg/dl, his ACTH level was 195.7 pg/ml, and his urinary free cortisol level was 2109 μg/day. Serum cortisol was not suppressed with the administration of high-dose dexamethasone. Imaging showed separate masses in both the sphenoid sinus and the pituitary gland, complicating the diagnostic process and requiring pathological assessment of both masses. No other abnormalities were found on thoracic, abdominal, or pelvic scans. Gross-total resection of both lesions was accomplished via an endoscopic endonasal transsphenoidal approach. Pathology confirmed an ectopic ACTH pituitary adenoma of the sphenoid sinus and a Crooke hyaline change of the pituitary gland. The patient achieved stable hormonal remission without significant postoperative complications, returned to full activity within 3 months, and remained disease free nearly 1 year after tumor resection. In a systematic literature review, the authors identified 41 cases of ectopic ACTH-secreting pituitary adenomas, including 18 arising in the sphenoid sinus without direct involvement of the sella. Including the case described here, the total number of ectopic ACTH pituitary adenomas arising in the sphenoid sinus was 19, and the total number of ectopic ACTH pituitary adenomas without regard to location was 42. For the 19 patients with adenomas found in the sphenoid sinus, ages ranged

  1. The analysis of clinical effect for endoscopic sinus surgery in the treatment of recurrent chronic sinusitis and nasal polyps%复发性慢性鼻窦炎鼻息肉的鼻内镜手术治疗的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    张炜; 范崇盛; 薛柯凡; 刘亚男; 王红洛

    2012-01-01

    OBJECTIVE To investigate the clinical efficacy for nasal endoscopic surgery in the treatment of the recurrent sinus and nasal polyps. METHODS The clinical effects and complications of 325 cases with recurrent chronic sinusitis and nasal polyps by endoscopic sinus surgery were analyzed retrospectively. The clinical effect for endoscopic sinus surgery in the treatment of recurrent chronic sinusitis and nasal polyps was evaluated comprehensively. RESULTS 325 patients were taken the implementation of endoscopic sinus surgery, which carried out the first sinus surgery in 157 cases. 135 patients were cured after endoscopic nasal surgery, the cure rate was 85.99%. 93 cases were conducted with 2 sinus surgery after endoscopic nasal surgery, 69 cases were cured, and the cure rate was 73.91%. 52 cases were with three sinus surgery, 31 cases were cured, and the cure rate was 59.61%.23 cases were taken the implementation of over 4 sinus surgery, 11 cases were cured, and the cure rate was 47.83%. The cure rate for different patients with sinus surgery was significantly different (P < 0.05). The incidence of complications after endoscopic nasal surgery was increasing with the increase in the number of sinus surgery. CONCLUSION The endoscopic sinus surgery can cure for recurrent patients with chronic sinusitis and nasal polyps effectively. But the cure rate of endoscopic sinus surgery is declining with the increase in the number of relapses sinus surgery. So we should take endoscopic sinus surgery as soon as possible for recurrence in patients to avoid the decrease of treatment efficacy for the repeated incidence.%目的 探讨鼻内镜手术用于复发性鼻窦鼻息肉的临床疗效.方法 回顾性分析325例复发性慢性鼻窦炎鼻患内患者采用鼻内镜手术治疗的临床效果及并发症情况,综合评价鼻内镜手术在复发性慢性鼻窦鼻患肉治疗的临床效果.结果 325例患者均实施鼻内镜手术,其中进行过1次鼻窦手术者157

  2. ETHMOIDAL SINUSITIS WITH PRESEPTAL ABSCESS: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Vikramjit

    2014-08-01

    Full Text Available Complications of sinusitis are rare nowadays because of higher and broad spectrum antibiotics. Preseptal abscess may rarely present as a complication of sinusitis. Our patient presented with a preseptal abscess with underlying ethmoidal sinusitis. The patient was treated with antibiotics; Incision and drainage of the preseptal abscess were done and infection in the ethmoidal sinuses was eradicated by endoscopic sinus surgery

  3. Computer-aided design of conveyor belts

    Energy Technology Data Exchange (ETDEWEB)

    Karolewski, B.; Pytel, J.

    1984-01-01

    Possibilities are discussed for using mathematical models of belt conveyors for development of computer-aided design of conveyors for coal mining. Examples of optimization tasks and methods for their solution using computerized simulation are analyzed. The analysis is illustrated by an algorithm used to design a starter for the drive system of a belt conveyor. Electromagnetic moment and starting current are used as optimization criteria. A simplified model of a belt conveyor is used. The model consists of an equation of motion with variable braking moment and variable moment of inertia. 3 references.

  4. Genetic algorithms in computer aided inductor design

    Directory of Open Access Journals (Sweden)

    Jean Fivaz

    2004-09-01

    Full Text Available The goal of this investigation is to determine the advantages of using genetic algorithms in computer-aided design as applied to inductors.  These advantages are exploited in design problems with a number of specifications and constraints, as encountered in power electronics during practical inductor design. The design tool should be able to select components, such as cores and wires, from databases of available components, and evaluate these choices based on the components’ characteristic data read from a database of manufacturers’ data-sheets.  The proposed design must always be practically realizable, as close to the desired specifications as possible and within any specified constraints.

  5. Computer Aided Modelling – Opportunities and Challenges

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    -based solutions to significant problems? The important issues of workflow and data flow are discussed together with fit-for-purpose model development. As well, the lack of tools around multiscale modelling provides opportunities for the development of efficient tools to address such challenges. The ability......This chapter considers the opportunities that are present in developing, extending and applying aspects of computer-aided modelling principles and practice. What are the best tasks to be done by modellers and what needs the application of CAPE tools? How do we efficiently develop model...... and opportunities are discussed for such systems....

  6. Quality indexing with computer-aided lexicography

    Science.gov (United States)

    Buchan, Ronald L.

    1992-01-01

    Indexing with computers is a far cry from indexing with the first indexing tool, the manual card sorter. With the aid of computer-aided lexicography, both indexing and indexing tools can provide standardization, consistency, and accuracy, resulting in greater quality control than ever before. A brief survey of computer activity in indexing is presented with detailed illustrations from NASA activity. Applications from techniques mentioned, such as Retrospective Indexing (RI), can be made to many indexing systems. In addition to improving the quality of indexing with computers, the improved efficiency with which certain tasks can be done is demonstrated.

  7. Computer-aided power systems analysis

    CERN Document Server

    Kusic, George

    2008-01-01

    Computer applications yield more insight into system behavior than is possible by using hand calculations on system elements. Computer-Aided Power Systems Analysis: Second Edition is a state-of-the-art presentation of basic principles and software for power systems in steady-state operation. Originally published in 1985, this revised edition explores power systems from the point of view of the central control facility. It covers the elements of transmission networks, bus reference frame, network fault and contingency calculations, power flow on transmission networks, generator base power setti

  8. Speech-enabled Computer-aided Translation

    DEFF Research Database (Denmark)

    Mesa-Lao, Bartolomé

    2014-01-01

    The present study has surveyed post-editor trainees’ views and attitudes before and after the introduction of speech technology as a front end to a computer-aided translation workbench. The aim of the survey was (i) to identify attitudes and perceptions among post-editor trainees before performing...... a post-editing task using automatic speech recognition (ASR); and (ii) to assess the degree to which post-editors’ attitudes and expectations to the use of speech technology changed after actually using it. The survey was based on two questionnaires: the first one administered before the participants...

  9. Mental distress and effort to engage an image-guided navigation system in the surgical training of endoscopic sinus surgery: a prospective, randomised clinical trial.

    Science.gov (United States)

    Theodoraki, M N; Ledderose, G J; Becker, S; Leunig, A; Arpe, S; Luz, M; Stelter, K

    2015-04-01

    The use of image-guided navigation systems in the training of FESS is discussed controversy. Many experienced sinus surgeons report a better spatial orientation and an improved situational awareness intraoperatively. But many fear that the navigation system could be a disadvantage in the surgical training because of a higher mental demand and a possible loss of surgical skills. This clinical field study investigates mental and physical demands during transnasal surgery with and without the aid of a navigation system at an early stage in FESS training. Thirty-two endonasal sinus surgeries done by eight different trainee surgeons were included. After randomization, one side of each patient was operated by use of a navigation system, the other side without. During the whole surgery, the surgeons were connected to a biofeedback device measuring the heart rate, the heart rate variability, the respiratory frequency and the masticator EMG. Stress situations could be identified by an increase of the heart rate frequency and a decrease of the heart rate variability. The mental workload during a FESS procedure is high compared to the baseline before and after surgery. The mental workload level when using the navigation did not significantly differ from the side without using the navigation. Residents with more than 30 FESS procedures already done, showed a slightly decreased mental workload when using the navigation. An additional workload shift toward the navigation system could not be observed in any surgeon. Remarkable other stressors could be identified during this study: the behavior of the supervisor or the use of the 45° endoscope, other colleagues or students entering the theatre, poor vision due to bleeding and the preoperative waiting when measuring the baseline. The mental load of young surgeons in FESS surgery is tremendous. The application of a navigation system did not cause a higher mental workload or distress. The device showed a positive effort to engage

  10. Integrated computer-aided design using minicomputers

    Science.gov (United States)

    Storaasli, O. O.

    1980-01-01

    Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM), a highly interactive software, has been implemented on minicomputers at the NASA Langley Research Center. CAD/CAM software integrates many formerly fragmented programs and procedures into one cohesive system; it also includes finite element modeling and analysis, and has been interfaced via a computer network to a relational data base management system and offline plotting devices on mainframe computers. The CAD/CAM software system requires interactive graphics terminals operating at a minimum of 4800 bits/sec transfer rate to a computer. The system is portable and introduces 'interactive graphics', which permits the creation and modification of models interactively. The CAD/CAM system has already produced designs for a large area space platform, a national transonic facility fan blade, and a laminar flow control wind tunnel model. Besides the design/drafting element analysis capability, CAD/CAM provides options to produce an automatic program tooling code to drive a numerically controlled (N/C) machine. Reductions in time for design, engineering, drawing, finite element modeling, and N/C machining will benefit productivity through reduced costs, fewer errors, and a wider range of configuration.

  11. Computer-aided light sheet flow visualization

    Science.gov (United States)

    Stacy, Kathryn; Severance, Kurt; Childers, Brooks A.

    1993-01-01

    A computer-aided flow visualization process has been developed to analyze video images acquired from rotating and translating light sheet visualization systems. The computer process integrates a mathematical model for image reconstruction, advanced computer graphics concepts, and digital image processing to provide a quantitative and visual analysis capability. The image reconstruction model, based on photogrammetry, uses knowledge of the camera and light sheet locations and orientations to project two-dimensional light sheet video images into three-dimensional space. A sophisticated computer visualization package, commonly used to analyze computational fluid dynamics (CFD) data sets, was chosen to interactively display the reconstructed light sheet images, along with the numerical surface geometry for the model or aircraft under study. A description is provided of the photogrammetric reconstruction technique, and the image processing and computer graphics techniques and equipment. Results of the computer aided process applied to both a wind tunnel translating light sheet experiment and an in-flight rotating light sheet experiment are presented. The capability to compare reconstructed experimental light sheet images and CFD solutions in the same graphics environment is also demonstrated.

  12. Analysis of effect of three under nasal endoscope surgery in the treatment of maxillary sinus cyst%鼻窥镜下三种术式治疗上颌窦囊肿效果分析

    Institute of Scientific and Technical Information of China (English)

    刘联合; 叶玉清; 程晋甫; 苏宏

    2015-01-01

    目的:探讨鼻窥镜下三种手术方式治疗上颌窦囊肿的临床疗效。方法选择上颌窦囊肿患者95例,分别采用上颌窦窦口开放扩大术、下鼻道上颌窦开窗术以及上颌窦前壁开窗术三种手术方式进行治疗,术后随访1年,分析三种手术方式的临床疗效。结果经上颌窦窦口开放扩大术39例,痊愈37例,2例复发;经下鼻道上颌窦开窗术27例,痊愈26例,1例复发;经上颌窦前壁开窗术29例,29例痊愈;三种手术方式治愈率差异无统计学意义(P >0.05)。结论治疗上颌窦囊肿术式的选择应根据囊肿的部位、大小以及是否伴有鼻-鼻窦疾病等多种因素确定。囊肿靠近窦口周围、窦腔外侧壁或伴有鼻窦疾病的上颌窦囊肿可采用上颌窦窦口开放扩大径路进行手术;靠近窦腔内侧壁、底壁的可采用下鼻道开窗径路;靠近窦腔前壁以及囊肿巨大或复发者可选择上颌窦前壁开窗手术径路;目的是达到彻底摘除囊肿,减轻组织损伤和并发症的发生。%Objective To explore three under nasal endoscope surgery treatment the clinical curative effect of maxillary sinus cyst.Methods 95 cases of maxillary sinus cyst patients were chosen,the maxillary sinus were used respectively to open to expand,the nasal passages of maxillary sinus fenestration and maxillary sinus anterior wall fen-estration three types of surgical treatment,postoperative follow -up of 1 year,the clinical curative effect of three kinds of operation method were analyzed.Results The maxillary sinus mouth open expansion of 39 cases during operation,37 cases were cured,2 cases of recurrence;The nasal passages under the maxillary sinus fenestration 27 cases, 26 cases cured,1 case of recurrence;The maxillary sinus anterior wall fenestration 29 cases,29 cases healed;Three kinds of operation cure rate difference had no statistical significance(P >0.05).Conclusion The treatment of max

  13. Fungal Sinusitis

    Science.gov (United States)

    ... Marketplace Find an ENT Doctor Near You Fungal Sinusitis Fungal Sinusitis Patient Health Information News media interested ... sinusitis results. There Are Four Types Of Fungal Sinusitis: Mycetoma Fungal Sinusitis produces clumps of spores, a " ...

  14. Cost of outpatient endoscopic sinus surgery from the perspective of the Canadian government: a time-driven activity-based costing approach.

    Science.gov (United States)

    Au, Jennifer; Rudmik, Luke

    2013-09-01

    The time-driven activity-based costing (TD-ABC) method is a novel approach to quantify the costs of a complex system. The aim of this study was to apply the TD-ABC technique to define the overall cost of a routine outpatient endoscopic sinus surgery (ESS) from the perspective of the Canadian government payer. Costing perspective was the Canadian government payer. All monetary values are in Canadian dollars as of December 2012. Costs were obtained by contacting staff unions, reviewing purchasing databases and provincial physician fee schedules. Practical capacity time values were collected from the College and Association of Registered Nurses of Alberta. Capacity cost rates ($/min) were calculated for all staff, capital equipment, and hospital space. The overall cost for routine outpatient ESS was $3510.31. The cost per ESS case for each clinical pathway encounter was as follows: preoperative holding ($49.19); intraoperative ($3296.60); sterilization ($90.20); postanesthesia care unit ($28.64); and postoperative day ward ($45.68). The 3 major cost drivers were physician fees, disposable equipment, and nursing costs. The intraoperative phase contributed to 94.5% of the overall cost. This study applied the TD-ABC method to evaluate the cost of outpatient ESS from the perspective of the Canadian government payer and defined the overall cost to be $3510.31 per case. © 2013 ARS-AAOA, LLC.

  15. A Study to Compare the Quality of Surgical Field Using Total Intravenous Anesthesia (with Propofol) versus Inhalational Anesthesia (with Isoflurane) for Functional Endoscopic Sinus Surgeries

    Science.gov (United States)

    Aujla, K. S.; Kaur, Manbir; Gupta, Ruchi; Singh, Sukhjinder; Bhanupreet; Tavleen

    2017-01-01

    Background and Objectives: Functional endoscopic sinus surgery (FESS) being a delicate technique, intraoperative bleeding is one of the major challenges. Even a little bleeding can adversely affect the surgeon's ability to visualize the region to be operated. General anesthesia is preferred over topical anesthesia in FESS. This study was conducted to compare the surgical field using total intravenous anesthesia (TIVA) with propofol and inhalational anesthesia with isoflurane for FESS. Secondary outcomes such as intraoperative blood loss and the incidence of perioperative complications were also recorded. Subjects and Methods: A total of sixty patients in the age group of 16–60 years with physical status American Society of Anesthesiologists Classes I and II, undergoing FESS were randomly divided into two groups of thirty each after taking informed consent and approval from the Hospital Ethics Committee. Thirty patients in Group I: received isoflurane-based inhalational anesthesia and other Thirty patients in Group II: were administered TIVA with propofol. Various parameters were recorded and statistically analyzed. Results: There was improved quality of surgical field at the end of surgery in the Group II as compared to Group I. Total blood loss during surgery and incidence of intraoperative complications were less in Group II as compared to Group I. Conclusion: This study concludes that in FESS, using TIVA with propofol decreases blood loss and the incidence of complications during surgery in addition to providing good quality of surgical field.

  16. Correlation of Lund-Mackay and SNOT-20 Before and After Functional Endoscopic Sinus Surgery (FESS: Does the Baseline Data Predict the Response Rate?

    Directory of Open Access Journals (Sweden)

    H. Moghadasi

    2009-12-01

    Full Text Available   "nBackground/Objective: To assess whether baseline SNOT-20 and Lund-Mackay score can predict response to FESS."n"n Materials and Methods: For 50 consecutive patients who underwent functional endoscopic sinus surgery (FESS for chronic rhinosinusitis (CRS in a university-affiliated hospital from January 2006 to February 2007, SNOT-20 and Lund-Mackay scores were evaluated preoperatively and after three months postoperatively. Results: Pearson's correlation coefficient of the Lund-Mackay score and SNOT-20 score was 0.77 before FESS and 0.73 after FESS (p <0.001. All multivariate regression models for evaluating whether the primary symptoms and CT scan findings predict the response rate showed a weak to moderate fitness to primary data based on all symptom domains and in each model, only the primary symptom domain of the dependent variable remain in the model. Conclusion: The outcome of FESS in patients with CRS is moderately related to primary symptoms according to SNOT-20 as well as the Lund-Mackay radiologic score.    "n  

  17. From Phonomecanocardiography to Phonocardiography computer aided

    Science.gov (United States)

    Granados, J.; Tavera, F.; López, G.; Velázquez, J. M.; Hernández, R. T.; López, G. A.

    2017-01-01

    Due to lack of training doctors to identify many of the disorders in the heart by conventional listening, it is necessary to add an objective and methodological analysis to support this technique. In order to obtain information of the performance of the heart to be able to diagnose heart disease through a simple, cost-effective procedure by means of a data acquisition system, we have obtained Phonocardiograms (PCG), which are images of the sounds emitted by the heart. A program of acoustic, visual and artificial vision recognition was elaborated to interpret them. Based on the results of previous research of cardiologists a code of interpretation of PCG and associated diseases was elaborated. Also a site, within the university campus, of experimental sampling of cardiac data was created. Phonocardiography computer-aided is a viable and low cost procedure which provides additional medical information to make a diagnosis of complex heart diseases. We show some previous results.

  18. Computer Aided in situ Cognitive Behavioral Therapy

    DEFF Research Database (Denmark)

    Chongtay, Rocio A.; Hansen, John Paulin; Decker, Lone

    2006-01-01

    This article describes the development of a system intended to aid the treatment of certain phobic conditions by the use of computer telephony integration (CTI).A phobia is an irrational fear to some situations or things and interferes with the functioning of the individual that suffers from it....... One of the most common and successfully used treatments for phobic conditions has been Cognitive Behavioral Therapy (CBT), which helps people learn to detect thinking patterns that trigger the irrational fear and to replace them with more realistic ideas. The health and financial impacts in society...... present a strong motivation to find ways to help in the treatment of these disorders. Access to treatment can be limited by the availability of trained mental health professionals, and more patients could get help if the therapist could delegate part of the treatment to computer-aided CBT. The system...

  19. Computer-Aided Design of Antimicrobial Peptides

    DEFF Research Database (Denmark)

    Fjell, Christopher D.; Hancock, Robert E.W.; Jenssen, Håvard

    2010-01-01

    chemical parameters with biological activities of the peptide, using statistical methods. In this review we will discuss two different in silico strategies of computer-aided antibacterial peptide design, a linear correlation model build as an extension of traditional principal component analysis (PCA......) and a non-linear artificial neural network model. Studies on structurally diverse peptides, have concluded that the PCA derived model are able to guide the antibacterial peptide design in a meaningful way, however requiring rather a high homology between the peptides in the test-set and the in silico...... library, to ensure a successful prediction. In contrast, the neural network model, though significantly less explored in relation to antimicrobial peptide design, has proven extremely promising, demonstrating impressive prediction success and ranking of random peptide libraries correlating well...

  20. Computer Aided Solvent Selection and Design Framework

    DEFF Research Database (Denmark)

    Mitrofanov, Igor; Conte, Elisa; Abildskov, Jens

    , millions of tons solvents have to be wasted every year [2]. Therefore, it becomes important to minimize and optimize the use of organic solvents as much as possible, to satisfy the “Green Chemistry Principles” [3]. Another challenge is that currently solvent selection relies very much on previous...... is to develop a systematic framework and implement it as software for selection and design of solvents for many applications including organic synthesis, complex reaction systems and solvent-based separations. The solvent selection framework is based on a combination of knowledge from industrial practice...... identification of solvent candidates using special software ProCAMD and ProPred, which are the implementations of computer-aided molecular techniques. The second consists of assigning the RS-indices following the reaction–solvent and then consulting the known solvent database and identifying the set of solvents...

  1. COMPUTER AIDED DESIGN OF CUTTING TOOLS

    Directory of Open Access Journals (Sweden)

    Jakub Matuszak

    2015-11-01

    Full Text Available Correct and stable machining process requires an appropriate cutting tool. In most cases the tool can be selected by using special tool catalogs often available in online version. But in some cases there is a need to design unusual tools, for special treatment, which are not available in tool manufacturers’ catalogs. Proper tool design requires strength and geometric calculations. Moreover, in many cases specific technical documentation is required. By using Computer Aided Design of cutting tools this task can be carried out quickly and with high accuracy. Cutting tool visualization in CAD programs gives a clear overview of the design process. Besides, these programs provide the ability to simulate real machining process. Nowadays, 3D modeling in CAD programs is a fundamental tool for engineers. Therefore, it is important to use them in the education process.

  2. Computer Aided Design Modeling for Heterogeneous Objects

    CERN Document Server

    Gupta, Vikas; Tandon, Puneet

    2010-01-01

    Heterogeneous object design is an active research area in recent years. The conventional CAD modeling approaches only provide geometry and topology of the object, but do not contain any information with regard to the materials of the object and so can not be used for the fabrication of heterogeneous objects (HO) through rapid prototyping. Current research focuses on computer-aided design issues in heterogeneous object design. A new CAD modeling approach is proposed to integrate the material information into geometric regions thus model the material distributions in the heterogeneous object. The gradient references are used to represent the complex geometry heterogeneous objects which have simultaneous geometry intricacies and accurate material distributions. The gradient references helps in flexible manipulability and control to heterogeneous objects, which guarantees the local control over gradient regions of developed heterogeneous objects. A systematic approach on data flow, processing, computer visualizat...

  3. [Evaluation of the impact of symptomatic gastroesophageal reflux disease on the result of surgical treatment with the use of endoscopic techniques and postoperative pharmacological treatment in patients with chronic sinusitis].

    Science.gov (United States)

    Nieckarz, Rafał; Szaleniec, Joanna; Hartwich, Patryk; Wróbel, Agnieszka; Hydzik-Sobocińska, Karolina; Muszyński, Piotr; Markiewicz, Beata; Turczynowski, Łukasz; Składzień, Jacek; Strek, Paweł

    2013-01-01

    It is estimated that in Europe 10% of adults suffer from chronic sinusitis. Chronic sinusitis can be caused by many different diseases that share chronic inflammation of the sinuses as a common symptom. Rhinitis can be caused by stomach acid coming up from the stomach into the esophagus, which successively can result in chronic sinusitis. The current gold standard for diagnosing GERD is--bothersome for the patient--24 h esophageal pH monitoring. This method can be unpleasant for the patients, which makes it less acceptable. Because of that the criteria for symptomatic GERD were made an alternative diagnostic way. We acknowledge that the presence of heartburn and stomach acid coming up from the stomach into the esophagus at least once a week can be diagnosed as symptomatic GERD. The aim of the study is the assessment of the frequency of symptomatic GERD in patients operated because of chronic sinusitis and impact of symptomatic GERD on the follow-up treatment up to 12 months after endoscopic nasal surgery. The authors analysed 144 patients operated at the JUCM Otolaryngological Clinic in Kraków between 2011 and 2013 because of sinusitis. The inclusion criteria were: diagnosed chronic sinusitis, indications for endoscopic sinus surgery, and a written consent for the research. Each patient was examined laryngologically and surveyed. Patients were divided into two groups: with and without symptomatic GERD. We analysed the symptoms in patients treated for sinusitis with or without GERD before, between 3 and 6 as well as in the 12th month after endonasal surgery. Moreover, we analysed the intensity of the global symptoms (expressed in the VAS scale) and separately for each of the 13 symptoms of chronic sinusitis (expressed on a scale 0 - 3). We established that 33 out of the 144 patients (22.9%) qualified for the first survey reported the symptoms of GERD. In the second survey, which was conducted between 3 and 6 month after ESS, 24 out of 119 (20%) people reported the

  4. Removal of Supernumerary Teeth Utilizing a Computer-Aided Design/Computer-Aided Manufacturing Surgical Guide.

    Science.gov (United States)

    Jo, Chanwoo; Bae, Doohwan; Choi, Byungho; Kim, Jihun

    2017-05-01

    Supernumerary teeth need to be removed because they can cause various complications. Caution is needed because their removal can cause damage to permanent teeth or tooth germs in the local vicinity. Surgical guides have recently been used in maxillofacial surgery. Because surgical guides are designed through preoperative analysis by computer-aided design software and fabricated using a 3-dimensional printer applying computer-aided manufacturing technology, they increase the accuracy and predictability of surgery. This report describes 2 cases of removal of a mesiodens-1 from a child and 1 from an adolescent-using a surgical guide; these would have been difficult to remove with conventional surgical methods. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  5. The clinical effect of endoscopic sinus surgery for chronic sinusitis and its relationship with clinical classification%鼻内镜手术治疗慢性鼻窦炎的疗效及其与临床分期的关系

    Institute of Scientific and Technical Information of China (English)

    郑锋

    2015-01-01

    Objective:To observe the therapeutic effect of endoscopic sinus surgery for chronic sinusitis and its relationship with clinical classification.Methods:84 patients with chronic sinusitis were selected,they were randomly divided into the two groups on average,patients in the control group were treated with traditional operation,while patients in the observation group were treated by endoscopic surgery,The two groups were followed up for 1 year,we compared the clinical efficacy.Results:The total effective rate of the observation group was 71.43% better than that of the control group 92.86%,the difference was statistically significant(P<0.05).The total effective rate of type I and type Ⅱ were significantly higher than that of type Ⅲ,the recurrence rate of sinusitis in the observation group was significantly lower than that of the control group(P<0.05).Conclusion:Endoscopic sinus surgery for chronic sinusitis can improve the clinical efficacy of patients,reduce the recurrence rate of postoperative sinusitis.%目的:观察鼻内镜手术治疗慢性鼻窦炎的疗效及其与临床分期的关系。方法:收治慢性鼻窦炎患者84例,随机平分为两组,对照组采用传统手术治疗,观察组采用鼻内镜手术治疗,两组术后均随访1年,比较术后临床疗效。结果:观察组治疗后总有效率92.86%,优于对照组的71.43%,差异有统计学意义(P<0.05);Ⅰ型、Ⅱ型总有效率均显著高于Ⅲ型;观察组术后鼻窦炎复发率显著低于对照组(P<0.05)。结论:鼻内镜手术治疗慢性鼻窦炎可提高患者的临床疗效,降低术后鼻窦炎的复发率。

  6. 鼻窦灌注液冲洗在慢性鼻窦炎鼻内镜术后的应用及其机制探讨%Mechanism for the curative effect of douching with nasal sinuses perfusate in treating chronic sinusitis after endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    王芳; 王丹; 范晶晶

    2012-01-01

    Objective To investigate the mechanism for the curative effect of douching with nasal sinuses perfusate in treating chronic sinusitis after endoscopic sinus surgery.Methods Seventy-six chronic sinusitis patients after endoscopic sinus surgery were divided into treatment group and control group by random digits table with 38 cases each.Every group was given postoperatively sinus flush,treatment group was flushed with nasal sinuses perfusate,while contro group was flushed with 0.9% sodium chloride.Therapeutic effect was evaluated after two months.The therapeutic effects of the two groups were compared and the inflammation factor levels and changes of sinus mucosa were observed before and after treatment.Results In treatment group,there were 21 cases to be cured,13 cases to be improved,4 cases to be useless,the total effective rate was 89.5%(34/38),while in control group,there were 12 cases to be cured,15 cases to be improved,11 cases to be useless,the total effective rate was 71.1%(27/38),the total effective rates between two groups were statistically significant (P <0.05).The levels of interferon (IFN)-γ,interleukin(IL)-2,IL-4,IL-5 after treatment in treatment group were respectively ( 13.21 ± 1.38),( 14.59 ±1.43 ),(34.83 ± 5.31 ),( 39.93 ± 7.98 ) pg/L,which were significantly decreased compared with those before treatment [ (23.87 ± 1.76),( 16.13 ± 1.71 ),(67.37 ± 7.36),(81.82 ± 7.69) pg/L,P < 0.05 ].The levels of IFN- γ,IL-2,IL-4,IL-5 after treatment in control group were respectively (20.13 ± 2.73 ),( 14.82 ± 2.26),(48.92 ±7.62),(43.87 ±8.25) pg/L,which were significantly decreased compared with those before treatment [ (24.06 ± 1.82 ),( 15.96 ± 1.74),(66.81 ± 8.24),(82.16 ± 7.34) pg/L,P < 0.05 ].And the levels of IFN- γ,IL-4,IL-5 after treatment in treatment group were significantly lower than those in control group,the differences were statistically significant (P < 0.05).Conclusions That nasal flush with nasal sinuses perfusate

  7. Software For Computer-Aided Design Of Control Systems

    Science.gov (United States)

    Wette, Matthew

    1994-01-01

    Computer Aided Engineering System (CAESY) software developed to provide means to evaluate methods for dealing with users' needs in computer-aided design of control systems. Interpreter program for performing engineering calculations. Incorporates features of both Ada and MATLAB. Designed to be flexible and powerful. Includes internally defined functions, procedures and provides for definition of functions and procedures by user. Written in C language.

  8. Computer-Aided Parallelizer and Optimizer

    Science.gov (United States)

    Jin, Haoqiang

    2011-01-01

    The Computer-Aided Parallelizer and Optimizer (CAPO) automates the insertion of compiler directives (see figure) to facilitate parallel processing on Shared Memory Parallel (SMP) machines. While CAPO currently is integrated seamlessly into CAPTools (developed at the University of Greenwich, now marketed as ParaWise), CAPO was independently developed at Ames Research Center as one of the components for the Legacy Code Modernization (LCM) project. The current version takes serial FORTRAN programs, performs interprocedural data dependence analysis, and generates OpenMP directives. Due to the widely supported OpenMP standard, the generated OpenMP codes have the potential to run on a wide range of SMP machines. CAPO relies on accurate interprocedural data dependence information currently provided by CAPTools. Compiler directives are generated through identification of parallel loops in the outermost level, construction of parallel regions around parallel loops and optimization of parallel regions, and insertion of directives with automatic identification of private, reduction, induction, and shared variables. Attempts also have been made to identify potential pipeline parallelism (implemented with point-to-point synchronization). Although directives are generated automatically, user interaction with the tool is still important for producing good parallel codes. A comprehensive graphical user interface is included for users to interact with the parallelization process.

  9. Intelligent Image Based Computer Aided Education (IICAE)

    Science.gov (United States)

    David, Amos A.; Thiery, Odile; Crehange, Marion

    1989-03-01

    Artificial Intelligence (AI) has found its way into Computer Aided Education (CAE), and there are several systems constructed to put in evidence its interesting advantages. We believe that images (graphic or real) play an important role in learning. However, the use of images, outside their use as illustration, makes it necessary to have applications such as AI. We shall develop the application of AI in an image based CAE and briefly present the system under construction to put in evidence our concept. We shall also elaborate a methodology for constructing such a system. Futhermore we shall briefly present the pedagogical and psychological activities in a learning process. Under the pedagogical and psychological aspect of learning, we shall develop areas such as the importance of image in learning both as pedagogical objects as well as means for obtaining psychological information about the learner. We shall develop the learner's model, its use, what to build into it and how. Under the application of AI in an image based CAE, we shall develop the importance of AI in exploiting the knowledge base in the learning environment and its application as a means of implementing pedagogical strategies.

  10. A computer-aided continuous assessment system

    Directory of Open Access Journals (Sweden)

    B. C.H. Turton

    1996-12-01

    Full Text Available Universities within the United Kingdom have had to cope with a massive expansion in undergraduate student numbers over the last five years (Committee of Scottish University Principals, 1993; CVCP Briefing Note, 1994. In addition, there has been a move towards modularization and a closer monitoring of a student's progress throughout the year. Since the price/performance ratio of computer systems has continued to improve, Computer- Assisted Learning (CAL has become an attractive option. (Fry, 1990; Benford et al, 1994; Laurillard et al, 1994. To this end, the Universities Funding Council (UFQ has funded the Teaching and Learning Technology Programme (TLTP. However universities also have a duty to assess as well as to teach. This paper describes a Computer-Aided Assessment (CAA system capable of assisting in grading students and providing feedback. In this particular case, a continuously assessed course (Low-Level Languages of over 100 students is considered. Typically, three man-days are required to mark one assessed piece of coursework from the students in this class. Any feedback on how the questions were dealt with by the student are of necessity brief. Most of the feedback is provided in a tutorial session that covers the pitfalls encountered by the majority of the students.

  11. Computer-aided design for metabolic engineering.

    Science.gov (United States)

    Fernández-Castané, Alfred; Fehér, Tamás; Carbonell, Pablo; Pauthenier, Cyrille; Faulon, Jean-Loup

    2014-12-20

    The development and application of biotechnology-based strategies has had a great socio-economical impact and is likely to play a crucial role in the foundation of more sustainable and efficient industrial processes. Within biotechnology, metabolic engineering aims at the directed improvement of cellular properties, often with the goal of synthesizing a target chemical compound. The use of computer-aided design (CAD) tools, along with the continuously emerging advanced genetic engineering techniques have allowed metabolic engineering to broaden and streamline the process of heterologous compound-production. In this work, we review the CAD tools available for metabolic engineering with an emphasis, on retrosynthesis methodologies. Recent advances in genetic engineering strategies for pathway implementation and optimization are also reviewed as well as a range of bionalytical tools to validate in silico predictions. A case study applying retrosynthesis is presented as an experimental verification of the output from Retropath, the first complete automated computational pipeline applicable to metabolic engineering. Applying this CAD pipeline, together with genetic reassembly and optimization of culture conditions led to improved production of the plant flavonoid pinocembrin. Coupling CAD tools with advanced genetic engineering strategies and bioprocess optimization is crucial for enhanced product yields and will be of great value for the development of non-natural products through sustainable biotechnological processes.

  12. Computer aided materials design; Keisanki zairyo sekkei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The questionnaire survey on the computer aided materials design (CAMD), and the survey of current domestic and overseas software concerned were carried out to clarify developmental issues. The current elementary technology of CAMD was also surveyed to study its several problems caused with a progress of material design technology due to drastic diffusion of CAMD. This project aims at establishment of a new demanded software, computer chemistry, focusing attention on functional materials such as catalyst, polymer and non-linear electronic materials. Microscopic simulation technology was mainly surveyed in fiscal 1996. Although some fruitful results have been obtained in the fields of medical and agricultural chemicals, organic compounds, proteins, catalysts and electronic materials, such some problems are pointed out as `CAMD cannot handle an actual size of the target system` and `commercially available software are very expensive.` Reliable tool development as elementary technology, and the verification of its applications are thus required. Meso-dynamics, polymers, surface reaction and integrated technological environment attract users` attention. 27 refs., 16 figs., 2 tabs.

  13. Computer Aided Diagnosis in Digital Mammography

    Directory of Open Access Journals (Sweden)

    "H. Mirzaalian

    2005-08-01

    Full Text Available Introduction & Background: Breast cancer is a lead-ing cause of cancer deaths among women.Early de-tection is the most effective way to reduce mortality. Mammography is the best method for early detection. In order to improve the accuracy of interpretation of mammogram, Computer Aided Diagnosis (CAD sys-tems have been proposed. The main goal of this re-search is to implement one of the algorithms and techniques for the enhancement of mammogram for easier detection of abnormalities. Patients & Methods: In the presented algorithm, morphological methods are used first for removing artifacts. Then thresholding, labeling, and active con-tours methods are used to extract the breast region, which allow the search for abnormalities to be lim-ited to the region of the breast. Finally, Gaussian fil-ter and White Top Hat Transform is used for contrast enhancement of mammogram. This algorithm has been applied on 50 images from Mammography Im-age Analysis Society (MIAS. An expert radiologist then verified improvement on the processed images. Results and Conclusions: Implementing the presented algorithm causes easier and better interpretation of mammogram without increasing the number of false positive and false negative results. Because of the spe-cial shapes and statistical features of abnormal tex-tures, it is possible to apply pattern recognition and artificial intelligence techniques as an aid for diagnos-ing suspicious regions. Research on using some of these techniques to distinguish benign abnormalities from malignant ones is on the way.

  14. Computer-Aided Drug Design Methods.

    Science.gov (United States)

    Yu, Wenbo; MacKerell, Alexander D

    2017-01-01

    Computational approaches are useful tools to interpret and guide experiments to expedite the antibiotic drug design process. Structure-based drug design (SBDD) and ligand-based drug design (LBDD) are the two general types of computer-aided drug design (CADD) approaches in existence. SBDD methods analyze macromolecular target 3-dimensional structural information, typically of proteins or RNA, to identify key sites and interactions that are important for their respective biological functions. Such information can then be utilized to design antibiotic drugs that can compete with essential interactions involving the target and thus interrupt the biological pathways essential for survival of the microorganism(s). LBDD methods focus on known antibiotic ligands for a target to establish a relationship between their physiochemical properties and antibiotic activities, referred to as a structure-activity relationship (SAR), information that can be used for optimization of known drugs or guide the design of new drugs with improved activity. In this chapter, standard CADD protocols for both SBDD and LBDD will be presented with a special focus on methodologies and targets routinely studied in our laboratory for antibiotic drug discoveries.

  15. Computer Aided Software Engineering workstation evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kotcher, D.A.; Parish, R.B.; Sisson, A.M.; Wenzel, W.A.; Wiancko, B.E.

    1988-09-14

    This report presents an evaluation of interconnected high performance workstations. The evaluation specifically addresses the benefits to personnel engaged in Computer Aided Software Engineering (CASE) for the design and development of computer software aided by computer workstations. To narrow the scope of the CASE evaluation to a reasonable size, the class of workstations considered was limited to units having the following minimum capabilities: speed to issue 2 to 3 million instructions per second (Mips), 4 megabytes (MB) of central memory, 140 MB of local disk storage, a monitor with 1024 by 960 graphics resolution, and Ethernet compatibility. In addition, software requirements included a virtual memory implementation of the UNIX operating system, the defacto standard networking Transmission Control Protocol and Internet Protocol (TCP/IP), and the network file system (NFS). Support of selected third-party software, such as the TEMPLATE graphics software, and robust tools for software development were also required. These criteria are justified by the use of workstations for maintenance and support of large mainframe based FORTRAN computer programs. The evaluation concluded that workstations are excellent tools for CASE. 1 ref., 1 fig., 6 tabs.

  16. Computer aided diagnosis of diabetic peripheral neuropathy

    Science.gov (United States)

    Chekh, Viktor; Soliz, Peter; McGrew, Elizabeth; Barriga, Simon; Burge, Mark; Luan, Shuang

    2014-03-01

    Diabetic peripheral neuropathy (DPN) refers to the nerve damage that can occur in diabetes patients. It most often affects the extremities, such as the feet, and can lead to peripheral vascular disease, deformity, infection, ulceration, and even amputation. The key to managing diabetic foot is prevention and early detection. Unfortunately, current existing diagnostic techniques are mostly based on patient sensations and exhibit significant inter- and intra-observer differences. We have developed a computer aided diagnostic (CAD) system for diabetic peripheral neuropathy. The thermal response of the feet of diabetic patients following cold stimulus is captured using an infrared camera. The plantar foot in the images from a thermal video are segmented and registered for tracking points or specific regions. The temperature recovery of each point on the plantar foot is extracted using our bio-thermal model and analyzed. The regions that exhibit abnormal ability to recover are automatically identified to aid the physicians to recognize problematic areas. The key to our CAD system is the segmentation of infrared video. The main challenges for segmenting infrared video compared to normal digital video are (1) as the foot warms up, it also warms up the surrounding, creating an ever changing contrast; and (2) there may be significant motion during imaging. To overcome this, a hybrid segmentation algorithm was developed based on a number of techniques such as continuous max-flow, model based segmentation, shape preservation, convex hull, and temperature normalization. Verifications of the automatic segmentation and registration using manual segmentation and markers show good agreement.

  17. 鼻内镜手术治疗慢性鼻窦炎患者的临床效果观察%Clinical Effect of Nasal Endoscopic Surgery in the Treatment of Chronic Sinusitis

    Institute of Scientific and Technical Information of China (English)

    李付国

    2016-01-01

    目的:研究鼻内镜手术治疗慢性鼻窦炎患者的临床效果。方法:选取2014年3月-2016年3月在本院慢性鼻窦炎患者100例,根据随机数字表法分为鼻内镜组和传统径路组两组,每组各50例。传统径路组采取传统经鼻外径路手术治疗,鼻内镜组采取鼻内镜手术治疗。两组患者慢性鼻窦炎治疗总有效率、临床复发率、鼻中隔和下鼻甲粘连、眶周软组织淤血、上颌窦开口狭窄等并发症发生率、术前术后生活质量进行比较。结果:鼻内镜组慢性鼻窦炎治疗总有效率98.00%明显高于传统径路组78.00%,两组比较差异有统计学意义(P0.05),术后鼻内镜组生活质量(92.02±5.53)分明显优于传统径路组(82.98±4.72)分,两组比较差异有统计学意义(P>0.05)。结论:鼻内镜手术治疗慢性鼻窦炎患者的临床效果确切,具有微创性、安全性,术中损伤小,可确切改善患者临床症状,减少并发症的发生,降低复发率,改善患者生活质量,值得推广应用。%Objective:To study the clinical effect of nasal endoscopic surgery in the treatment of patients with chronic sinusitis.Method:100 cases of chronic sinusitis in our hospital from March 2016 to March 2014 were selected and divided into two groups according to the random number table,50 cases of nasal endoscopic group and 50 cases in the traditional path group.Traditional route group was treated by traditional external nasal surgery, nasal endoscopic group was treated with nasal endoscopic surgery.The chronic sinusitis treatment total efficiency, clinical relapse rate,nasal septum and inferior turbinate adhesions,periorbital soft tissue congestion, maxillary sinus ostium stenosis and other complications, and quality life before and after surgery of two groups were compared. Result: The total effective rate of the nasal endoscopic group was 98.00% significantly higher than that of the traditional

  18. Sinus Headaches

    Science.gov (United States)

    ... Evaluation and management of "sinus headache" in the otolaryngology practice. Otolaryngology Clinics of North America. 2014;47:269. Sinusitis. ... et al. Why the confusion about sinus headache? Otolaryngology Clinics of North America. 2014;47:169. Sinus ...

  19. Effect of endoscopic sinus surgery on chronic rhinosinusitis%鼻内镜手术治疗慢性鼻-鼻窦炎疗效分析

    Institute of Scientific and Technical Information of China (English)

    崔雪峰

    2015-01-01

    ; SNOT-20 and 5 items score after one month , six months and twelve months were significantly decreased ( P<0.05) .Conclusions Endoscopic surgery treating chronic nasal si-nusitis operation can significantly reduce symptoms integral, improve postoperative quality of life, and has high clinical value.

  20. Clinical analysis on treatment of non- invasive fungal rhinosinusitis by endoscopic sinus surgery%鼻内镜手术治疗非侵袭性真菌性鼻-鼻窦炎临床分析

    Institute of Scientific and Technical Information of China (English)

    张世涛; 赵玉林; 苏红霞; 张远

    2011-01-01

    Objective To explore the etiology and clinical features of non - invasive fungal rhinosinusitis and to evaluate the methods and curative effects of endoscopic sinus surgery. Methods The denial and follow -up data of 57 patients with non -invasive fungal rhinosinusitis were retrospectively analyzed. Results All cases were cured without recurrence during a follow - up from 6 months to 2 years. Conclusions Anatomic abnormalities of the paranasal sinuses are the main reasons of the non invasive fungal rhinosinusitis, Clearing up the infected focus by endoscopic sinus surgery is an effective treatment, after surgery regularly sinus rinse and nasal endoscopy can prevent disease recurrence.%目的 探讨非侵袭性真菌性鼻-鼻窦炎的致病原因、临床特征、鼻内镜手术方法及临床疗效.方法 对2007年5月至2010年5月的57例非侵袭性真菌性鼻-鼻窦炎的临床资料进行回顾性分析.结果 随访6个月~2年,全部病例无复发,无1例并发症发生.结论 鼻腔、鼻窦局部解剖异常是非侵袭性真菌性鼻-鼻窦炎患者患病的主要原因,鼻内镜手术清除病灶是治疗非侵袭性真菌性鼻-鼻窦炎的最有效方法,手术后定期鼻窦窦腔冲洗及鼻内镜检查可防止疾病的复发.

  1. CAD/CAM (Computer Aided Design/Computer Aided Manufacture). A Brief Guide to Materials in the Library of Congress.

    Science.gov (United States)

    Havas, George D.

    This brief guide to materials in the Library of Congress (LC) on computer aided design and/or computer aided manufacturing lists reference materials and other information sources under 13 headings: (1) brief introductions; (2) LC subject headings used for such materials; (3) textbooks; (4) additional titles; (5) glossaries and handbooks; (6)…

  2. Retrofitting a crown to a sleep apnea device by using computer-aided design and computer-aided milling technology.

    Science.gov (United States)

    Biethman, Rick; Land, Martin F; Hruskocy, Heather; Colgin, Bruce

    2014-07-01

    Retrofitting a new crown to an existing dental device is challenging. The continued evolution of computer-aided design and computer-aided manufacturing (CAD/CAM) significantly simplifies the process. This article demonstrates retrofitting a gold crown to an existing sleep apnea device.

  3. Frequency of the odontogenic maxillary sinusitis extended to the anterior ethmoid sinus and response to surgical treatment

    Science.gov (United States)

    Crovetto-Martínez, Rafael; Martin-Arregui, Francisco J.; Zabala-López-de-Maturana, Aitor; Tudela-Cabello, Kiara

    2014-01-01

    Objectives: Odontogenic sinusitis usually affects the maxillary sinus but may extend to the anterior ethmoid sinuses. The purpose of this study is to determine the percentage of odontogenic maxillary sinusitis extended to the anterior ethmoid sinuses and determine also the surgical resolution differences between odontogenic maxillary sinusitis and odontogenic maxillary associated to anterior ethmoidal sinusitis. Study Design: This is a retrospective cohort study performed on 55 patients diagnosed of odontogenic sinusitis and treated surgically by functional endoscopic sinus surgery. Results: This study showed that 52.7% of odontogenic maxillary sinusitis spreads to anterior ethmoid, causing added anterior ethmoid sinusitis. We found that 92.3% of the odontogenic maxillary sinusitis (who underwent middle meatal antrostomy) and 96.5% of the odontogenic maxillary sinusitis extended to the anterior ethmoid (treated with middle meatal antrostomy and anterior ethmoidectomy) were cured. Conclusions: Ethmoid involvement is frequent in maxillary odontogenic sinusitis. The ethmoid involvement does not worsen the results of “functional endoscopic sinus surgery” applied to the odontogenic sinusitis. Key words:Odontogenic maxillary sinusitis, ethmoiditis, functional endoscopic sinus surgery. PMID:24608208

  4. 慢性鼻窦炎鼻内镜手术中额筛区骨瘤的处理%Surgical strategy for osteoma during endoscopic sinus surgery for chronic rhinosinusitis

    Institute of Scientific and Technical Information of China (English)

    葛文彤; 李云川; 倪鑫

    2013-01-01

    Objective To realize the characteristics of occurrence and distribution of osteoma found in patients undergoing endoscopic sinus surgery (ESS) due to chronic rhinosinusitis with or without nasal polyps (CRSwNP/CRSsNP),and to discuss the surgical strategy for this tumor.Methods Clinical data of 520 adult patients undergoing ESS due to CRSwNP/CRSsNP from Nov.2006 to Jan.2010 was analyzed retrospectively.The clinical data included the occurrence and location of osteoma,involvement of lamina papyracea/anterior skull base,surgical strategy for the tumor,surgical complications and so on.Results Osteoma was found in 26 of the 520 cases.The occurrence rate was 5% (26/520 cases),with the size of0.4 cm×0.4 cm ×0.4 cm to 1.5 cm ×1.5 cm× 3.0 cm.Most of them were isolated (23/26) and located in frontal sinus (13 cases) or anterior ethmoid sinus (11 cases).Involvement of anterior skull base and orbital wall was respctively found in 7 and 4 cases.Of all the 26 patients,20 cases were treated with complete endoscopic resection,2 with partial endoscopic resection,and 7 without any intervention.All patients had neither immediate nor long-term postoperative orbit/skull base complications.Conclusions Osteoma is not uncommon in CRSwNP/CRSsNP patients undergoing ESS.This tumor is usually isolated without apparent symptoms and occasionally found in sinus CT.Anterior ethmoid sinus and frontal sinus are most frequently involved.Complete endoscopic resection of the tumor can be achieved in most cases.Under the premise of ensuring sufficient drainage,partial endoscopic resection or nonintervention of the tumor is also acceptable.%目的 了解因慢性鼻-鼻窦炎伴/不伴鼻息肉(chronic rhinosinusitis with or without nasal polyps,CRSwNP/CRSsNP)接受ESS的患者中骨瘤的发病情况、分布特点,讨论其术中处理原则.方法 回顾分析2006年11月~2010年1月因CRSwNP/CRSsNP接受ESS的520例患者中26例患者合并骨瘤的发病情况、术中

  5. CT诊断和鼻内窥镜手术对真菌性鼻-鼻窦炎的诊治探讨%To explore the CT scanning and endoscopic sinus surgery in diagnosis and treatment of fungal rhinosinusitis.

    Institute of Scientific and Technical Information of China (English)

    杨羿容; 朱德姝; 吴勇

    2011-01-01

    目的 探讨真菌性鼻-鼻窦炎恰当的诊断及治疗方法.方法 回顾性对2005年4月~2009年4月我科收治的35例真菌性鼻-鼻窦炎的临床症状、CT表现及鼻内窥镜治疗效果分析.结果 35例真菌性鼻-鼻窦炎经鼻内窥镜下鼻窭开放手术后冲洗鼻窦治疗后随访6个月~2年,33例1次治愈,2例复发经再手术解除鼻窦口堵塞后用刮霉菌素冲洗鼻窦治疗后治愈,随访6个月无复发.结论 CT检查是诊断真菌性鼻-鼻窦炎的有效检查手段,鼻内窥镜下鼻窦开放后联合制霉菌素冲洗鼻窦是治疗真菌性鼻-鼻窦炎的有效方法.%Objective To study the pathological and clinicalfeatures of fungal sinusitis and its diagnosis and treatment methods. Methods The clinical symptoms, CT manifestations and treatments of fungal rhinosinusitis was analyzed retrospectively with data from 35 patients in our department between April 2005 and April 2009. All 35 patients were washed opened nasal sinus after endoscopic sinus surgery during a follow-up of 6 months to 2 years, Results among the 35 patients,33 patients had been cured. 2 had been healed after re-operation by using nystatin wash nasal sinus with 6 months of follow-up. Conclusion CT scanning is useful for the diagnosis of fungal rhinosinusitis. It's effective to cure the fungal rhinosinusitis with nystatin nasal sinus washouts after endoscopic sinus surgery.

  6. Computer-Aided Simulation of Mastoidectomy

    Institute of Scientific and Technical Information of China (English)

    CHEN He-xin; MA Zhi-chao; Wang Zhang-feng; GUO Jie-bo; WEN Wei-ping; XU Geng

    2008-01-01

    Objective To establish a three-dimensional model of the temporal bone using CT scan images for study of temporal bone structures and simulation of mastoidectomy procedures. Methods CT scan images from 6 individuals (12 temporal bones) were used to reconstruct the Fallopian canal, internal auditory canal, cochlea, semicircular canals, sigmoid sinus, posterior fossa floor and jugular bulb on a computer platform. Their anatomical relations within the temporal bone were restored in the computed model. The same model was used to simulate mastoidectomy procedures. Results The reconstructed computer model provided accurate and clear three-dimensional images of temporal bone structures. Simulation of mastoidectomy using these images provided procedural experiences closely mimicking the real surgical procedure. Conclusion Computeraided three dimensional reconstruction of temporal bone structures using CT scan images is a useful tool in surgical simulation and can aid surgical procedure planning.

  7. Microwave processing of a dental ceramic used in computer-aided design/computer-aided manufacturing.

    Science.gov (United States)

    Pendola, Martin; Saha, Subrata

    2015-01-01

    Because of their favorable mechanical properties and natural esthetics, ceramics are widely used in restorative dentistry. The conventional ceramic sintering process required for their use is usually slow, however, and the equipment has an elevated energy consumption. Sintering processes that use microwaves have several advantages compared to regular sintering: shorter processing times, lower energy consumption, and the capacity for volumetric heating. The objective of this study was to test the mechanical properties of a dental ceramic used in computer-aided design/computer-aided manufacturing (CAD/CAM) after the specimens were processed with microwave hybrid sintering. Density, hardness, and bending strength were measured. When ceramic specimens were sintered with microwaves, the processing times were reduced and protocols were simplified. Hardness was improved almost 20% compared to regular sintering, and flexural strength measurements suggested that specimens were approximately 50% stronger than specimens sintered in a conventional system. Microwave hybrid sintering may preserve or improve the mechanical properties of dental ceramics designed for CAD/CAM processing systems, reducing processing and waiting times.

  8. Conceptual framework for the integration of computer-aided design and computer-aided process planning

    Energy Technology Data Exchange (ETDEWEB)

    Li, R.K.

    1986-01-01

    This research presents a conceptual framework for the integration of Computer-Aided Design (CAD) and Computer-Aided Process Planning (CAPP). The conceptual framework resides in an environmental of N CAD systems and M CAPP systems. It consists of three major modules: a generic-part definition data structure, a preprocessor, and a postprocessor. The generic-part definition data structure was developed to serve as a neutral-part definition data representation between CAD and CAPP systems. With this structure, the number of interfacing systems can be reduced to 1 + M systems. The preprocessor, a part feature recognition system, is designed to extract part definition data from an IGES file, evaluates that data, allows inclusion of unsupported data, and finally puts the data into the data structure. The postprocessor was written to convert the data from the data structure to the part input format of a selected CAPP system. A prototype systems that uses IBM's CAD package (CADAM), IGES and United Technologies Research Center's CAPP package (CMPP) was developed to test and prove the concept of this research. The input is a CADAM graphic design file and the outputs are a summary of operations and a tolerance control chart which are ready to be used in the production shops.

  9. Adhesive Bonding to Computer-aided Design/ Computer-aided Manufacturing Esthetic Dental Materials: An Overview.

    Science.gov (United States)

    Awad, Mohamed Moustafa; Alqahtani, H; Al-Mudahi, A; Murayshed, M S; Alrahlah, A; Bhandi, Shilpa H

    2017-07-01

    To review the adhesive bonding to different computer-aided design/computer-aided manufacturing (CAD/CAM) esthetic restorative materials. The use of CAD/CAM esthetic restorative materials has gained popularity in recent years. Several CAD/ CAM esthetic restorative materials are commercially available. Adhesive bonding is a major determinant of success of CAD/ CAM restorations. Review result: An account of the currently available bonding strategies are discussed with their rationale in various CAD/ CAM materials. Different surface treatment methods as well as adhesion promoters can be used to achieve reliable bonding of CAD/CAM restorative materials. Selection of bonding strategy to such material is determined based on its composition. Further evidence is required to evaluate the effect of new surface treatment methods, such as nonthermal atmospheric plasma and self-etching ceramic primer on bonding to different dental ceramics. An understanding of the currently available bonding strategies to CA/CAM materials can help the clinician to select the most indicated system for each category of materials.

  10. Effect analysis of hiatus sinus maxillaris treatment with different methods during nasal endoscope paranasal sinuses operation%鼻内镜鼻窦手术中不同方法处理上颌窦自然口疗效分析

    Institute of Scientific and Technical Information of China (English)

    蒋晋安; 郑国玺; 徐大道

    2015-01-01

    Objective To explore the relationship between different treatment methods of hiatus sinus maxillaris during nasal endoscope paranasal sinuses operation and prognosis.Methods Eighty patients with chronic rhinosinusitis and rhinopolyp were divided into observation group and control group byrandom digits table method with 40 cases each.Expanding hiatus sinus maxillaris were given according to the modality of hiatus sinus maxillaris and lesion of maxillaris sinus in observation group.The patients in control group were given expanding hiatus sinus maxillaris.The opening rate of hiatus sinus maxillaris and postoperative complication were observed.Results All the patients were followed up ≥ 1 year.The opening rate of hiatus sinus maxillaris in observation group (97.5%,39/40) was significantly higher than that in control group (77.5%,31/40),the rate of postoperative complication in observation group (5.0%,2/40) was significantly lower than that in control group (27.5%,11/40),and there were statistical differences (P < 0.01).Conclusion Whether or not to enlarge hiatus sinus maxillaris during nasal endoscope paranasal sinuses operation should base on intraoperative specific situation,and it can reduce intraoperative injury,prevent the shutting of sinus and postoperative complication.%目的 探讨经鼻内镜鼻窦手术中不同方法处理上颌窦自然口与预后的关系.方法 将80例慢性鼻窦炎、鼻息肉患者按随机数字表法分为两组:试验组40例,术中根据上颌窦自然口形态与上颌窦本身的病变情况,扩大或不扩大上颌窦自然口;对照组40例,术中均扩大上颌窦自然口.观察两组上颌窦自然口开放率和术后并发症发生情况.结果 术后随访至少1年,试验组上颌窦自然口开放率明显高于对照组[97.5%(39/40)比77.5%(31/40)],术后并发症发生率明显低于对照组[5.0%(2/40)比27.5%(11/40)],差异有统计学意义(P<0.01).结论 鼻内镜鼻窦手术中是否扩

  11. Relatively light general anesthesia is more effective than fluid expansion in reducing the severity of epinephrine-induced hypotension during functional endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    LI Wei-yan; ZHOU Zhi-qiang; JI Jun-feng; LI Ze-qing; YANG Jian-jun; SHANG Ruo-jing

    2007-01-01

    Background Epinephrine infiltration of the nasal mucosa causes hypotension during functional endoscopic sinus surgery (FESS) under general anesthesia. A prospective randomized-controlled study was designed to determine whether relatively light general anesthesia is superior to fluid expansion in reducing epinephrine-induced hypotension during FESS.Methods Ninety patients undergoing elective FESS under general anesthesia were randomly assigned to three groups with 30 patients in each. Each patient received local infiltration with adrenaline-containing (5 μg/ml) lidocaine (1%,4 ml) under different conditions. For Group Ⅰ, anesthesia was maintained with propofol 2 μg/ml and rimifentanil 2 ng/ml by TCI. Group Ⅱ (control group) and Group Ⅲ received propofol 4 μg/ml and rimifentanil 4 ng/ml, respectively. In Groups Ⅰ and Ⅱ, fluid expansion was performed with hetastarch 5 mi/kg within 20 minutes; hetastarch 10 ml/kg was used in Group Ⅲ. Mean arterial pressure (MAP) and heart rate (HR) were recorded at 30-second-intervals for 5 minutes after the beginning of local infiltration. Simultaneously, the lowest and the highest MAP were recorded to calculate the mean maximum increase or decrease percent in MAP for all patients in each group. Data analysis was performed by χ2 test,one-way analysis of variance, or one-way analysis of covariance.Results Hemodynamic changes, particularly a decrease in MAP accompanied by an increase in HR at 1.5 minutes(P<0.05), were observed in all groups. The mean maximum decrease in MAP below baseline was 14% in Group Ⅰ, 24% in Group Ⅲ and 26% in Group Ⅱ. There were statistically significant differences between Group Ⅰ and Groups Ⅱ and Ⅲ(P<0.05). The mean maximum increase in MAP above baseline was 9% in Group Ⅰ, 6% in Group Ⅲ and 2% in Group Ⅱ.Conclusion Relatively light general anesthesia can reduce the severity of epinephrine-induced hypotension more effectively than fluid expansion during FESS under general

  12. Development and Evaluation of a Computer-Aided Learning (CAL ...

    African Journals Online (AJOL)

    Development and Evaluation of a Computer-Aided Learning (CAL) Package on C++ ... Technology has created a great potential for borderless education. ... packages in the future, thus roviding additional resources for independent learning.

  13. Computer Aided Design Tools for Extreme Environment Electronics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project aims to provide Computer Aided Design (CAD) tools for radiation-tolerant, wide-temperature-range digital, analog, mixed-signal, and radio-frequency...

  14. Computer-Aided Qualitative Data Analysis with Word

    Directory of Open Access Journals (Sweden)

    Bruno Nideröst

    2002-05-01

    Full Text Available Despite some fragmentary references in the literature about qualitative methods, it is fairly unknown that Word can be successfully used for computer-aided Qualitative Data Analyses (QDA. Based on several Word standard operations, elementary QDA functions such as sorting data, code-and-retrieve and frequency counts can be realized. Word is particularly interesting for those users who wish to have first experiences with computer-aided analysis before investing time and money in a specialized QDA Program. The well-known standard software could also be an option for those qualitative researchers who usually work with word processing but have certain reservations towards computer-aided analysis. The following article deals with the most important requirements and options of Word for computer-aided QDA. URN: urn:nbn:de:0114-fqs0202225

  15. Computer-aided Translation Technology and Its Applications

    Institute of Scientific and Technical Information of China (English)

    汪美侠; 何大顺

    2014-01-01

    This article begins with a brief analysis of the significance of translation technology in different spheres of modern life, followed by a distinction between machine translation (MT) and computer-aided translation (CAT). It then describes some trans-lation resources and tools and examines the negative and positive aspects of computer-aided translations. Finally it comes to a conclusion that it would be greatly efficient and productive for the translators to acquire the new skills in the translation work-place.

  16. Computer-aided design development transition for IPAD environment

    Science.gov (United States)

    Owens, H. G.; Mock, W. D.; Mitchell, J. C.

    1980-01-01

    The relationship of federally sponsored computer-aided design/computer-aided manufacturing (CAD/CAM) programs to the aircraft life cycle design process, an overview of NAAD'S CAD development program, an evaluation of the CAD design process, a discussion of the current computing environment within which NAAD is developing its CAD system, some of the advantages/disadvantages of the NAAD-IPAD approach, and CAD developments during transition into the IPAD system are discussed.

  17. [Diagnosis and treatment of fungal ball rhino-sinusitis].

    Science.gov (United States)

    Nie, Jun; Liu, Fenfang; Zhang, Hanwu; Li, Li

    2013-07-01

    To explore the diagnosis and treatment of the fungal ball rhino-sinusitis. The clinical data of 128 cases with the fungal ball rhino-sinusitis in our hospital between September 2005 and January 2012 were retrospectively analyzed. All patients were accepted nasal endoscopic surgery and followed up after surgery. The diagnosis were confirmed by postoperative pathological examination. The sinus of all patients epithelialized after the surgery from fourth to ninth weeks, one case recurred eight months later. Sinus CT scan and nasal endoscopy were very important to the diagnosis of the fungal ball rhino-sinusitis, and nasal endoscopic surgery is the most important treatment method to fungal ball rhino-sinusitis.

  18. PLAID- A COMPUTER AIDED DESIGN SYSTEM

    Science.gov (United States)

    Brown, J. W.

    1994-01-01

    PLAID is a three-dimensional Computer Aided Design (CAD) system which enables the user to interactively construct, manipulate, and display sets of highly complex geometric models. PLAID was initially developed by NASA to assist in the design of Space Shuttle crewstation panels, and the detection of payload object collisions. It has evolved into a more general program for convenient use in many engineering applications. Special effort was made to incorporate CAD techniques and features which minimize the users workload in designing and managing PLAID models. PLAID consists of three major modules: the Primitive Object Generator (BUILD), the Composite Object Generator (COG), and the DISPLAY Processor. The BUILD module provides a means of constructing simple geometric objects called primitives. The primitives are created from polygons which are defined either explicitly by vertex coordinates, or graphically by use of terminal crosshairs or a digitizer. Solid objects are constructed by combining, rotating, or translating the polygons. Corner rounding, hole punching, milling, and contouring are special features available in BUILD. The COG module hierarchically organizes and manipulates primitives and other previously defined COG objects to form complex assemblies. The composite object is constructed by applying transformations to simpler objects. The transformations which can be applied are scalings, rotations, and translations. These transformations may be defined explicitly or defined graphically using the interactive COG commands. The DISPLAY module enables the user to view COG assemblies from arbitrary viewpoints (inside or outside the object) both in wireframe and hidden line renderings. The PLAID projection of a three-dimensional object can be either orthographic or with perspective. A conflict analysis option enables detection of spatial conflicts or collisions. DISPLAY provides camera functions to simulate a view of the model through different lenses. Other

  19. 经鼻内镜治疗累及蝶窦的中颅底占位性病变%The management of space-occupying lesion of middle skull base involving sphenoid sinus by transnasal endoscopic surgery

    Institute of Scientific and Technical Information of China (English)

    刘丹丹; 韩红蕾; 刘洋; 张秋航

    2009-01-01

    Objective:To investigate the diagnosis and therapy of space-occupying lesion of middle skull base involving sphenoid sinus.Method:A retrospective analysis was performed. Eighteen patients with extradural space-occupying lesion of middle skull base involving sphenoid sinus underwent transnasal endoscopic surgery.Result:One case of primary empty sella turcica was misdiagnosed as sphenoidal sinus cyst. One case of fibrous dysplasia and one case of meningioma were all misdiagnosed as mycotic sphenoiditis. Total rate of misdiagnosis was 16.7%.Among the 18 cases, 17 cases underwent complete resection of the lesion, and only 1 case underwent major resection of the lesion. The amount of blood loss during surgery ranged between 100 ml and 2500 ml.One case had bacterial meningitis which was cured after corresponding treatment. One case was blind in both eyes. And the other case died of pulmonary embolism.Conclusion:Transnasal endoscopic surgery is feasible and practical to treat benign space-occupying lesion of sphenoidal sinus and extradural lesion of middle skull base involving sphenoidal sinus. Definite diagnosis, accurate location and careful operation are important to complete the surgery successfully.%目的:探讨累及蝶窦的中颅底占位性病变的诊断治疗方法.方法:对18例累及蝶窦的中颅底硬膜外占位病变患者施行经鼻内镜手术.结果:1例原发性空蝶鞍误诊为蝶窦囊肿,1例骨纤维异常增殖、1例脑膜瘤误诊为真菌性蝶窦炎,误诊率为16.7%.17例全部切除病变,1例大部分切除肿瘤.术中出血量100~2500 ml.15例治愈,无并发症;1例并发细菌性脑膜炎治愈;1例双眼失明;1例因肺栓塞死亡.结论:经鼻内镜治疗蝶窦和累及蝶窦的中颅底硬膜外良性占位性病变可行.术前明确诊断、术中准确定位和仔细操作是手术成功的重要保证.

  20. A review of computer-aided design/computer-aided manufacture techniques for removable denture fabrication.

    Science.gov (United States)

    Bilgin, Mehmet Selim; Baytaroğlu, Ebru Nur; Erdem, Ali; Dilber, Erhan

    2016-01-01

    The aim of this review was to investigate usage of computer-aided design/computer-aided manufacture (CAD/CAM) such as milling and rapid prototyping (RP) technologies for removable denture fabrication. An electronic search was conducted in the PubMed/MEDLINE, ScienceDirect, Google Scholar, and Web of Science databases. Databases were searched from 1987 to 2014. The search was performed using a variety of keywords including CAD/CAM, complete/partial dentures, RP, rapid manufacturing, digitally designed, milled, computerized, and machined. The identified developments (in chronological order), techniques, advantages, and disadvantages of CAD/CAM and RP for removable denture fabrication are summarized. Using a variety of keywords and aiming to find the topic, 78 publications were initially searched. For the main topic, the abstract of these 78 articles were scanned, and 52 publications were selected for reading in detail. Full-text of these articles was gained and searched in detail. Totally, 40 articles that discussed the techniques, advantages, and disadvantages of CAD/CAM and RP for removable denture fabrication and the articles were incorporated in this review. Totally, 16 of the papers summarized in the table. Following review of all relevant publications, it can be concluded that current innovations and technological developments of CAD/CAM and RP allow the digitally planning and manufacturing of removable dentures from start to finish. As a result according to the literature review CAD/CAM techniques and supportive maxillomandibular relationship transfer devices are growing fast. In the close future, fabricating removable dentures will become medical informatics instead of needing a technical staff and procedures. However the methods have several limitations for now.

  1. Treatment of complex maxillary sinus disease through the frontal recess of tears operation under endoscope%鼻内镜下泪前隐窝入路手术治疗复杂上颌窦病变

    Institute of Scientific and Technical Information of China (English)

    胡煜; 孙敬武

    2012-01-01

    Objective To explore the feasibility, efficacy and complications of the frontal recess of tears operation to completely remove maxillary sinus lesions under endoscope in the complex maxillary sinus disease. Methods From June 2008 to June 2010, we retrospectively analyzed the clinical data of 26 cases getting different types of the complex maxillary sinus disease which were treated by the frontal recess of tears operation. Among 26 cases: 17 cases got inverted papilloma: 4 cases got hemorrhagic and necrotic polyps: 3 cases got recurrent maxillary sinusitis with cysts: 1 case got recurrent nasal polyps: 1 case got maxillary sinus osteoma. All patients underwent CT examination. The cases with inverted papillomaline underwent MR examination. Nasal and other sinus lesions were firstly removed and the natural maxillary sinus ostium were opened and expanded. Then the maxillary sinus lesions were removed by the frontal recess of tears operation. Following this operation , the inferior meatus after fenestration were performed. The complications and postoperative effect were observed. Results In all patients, every maxillary sinus walls were well exposed. The lesions were completely removed. The operations have done well without nasolacrimal duct injury, turbinate atrophy and necrosis, complications such as the facial numbness. All the cases had 12-36 months follow-up. Two cases with inverted papillomaline showed recurrence. One of them got a recurrence in the junction of top of the mouth of the maxillary sinus and the bottom of the orbital after surgery for 3 months. After the surgical removal of the lesions and next 1 year follow-up, no recurrence was found. Another case of them got a local recurrence in the ethmoid sinus involving the orbital ethmoid cardboard after surgery for 7 months. After the surgical removal of the lesions and local orbital cardboard and next 8 months follow-up, no recurrence was observed. The recurrence was not found in all other cases. All

  2. Sinus Surgery

    Science.gov (United States)

    ... the surgical strategy was to remove all sinus mucosa from the major sinuses. The use of an ... improved drainage system is achieved, the diseased sinus mucosa has an opportunity to return to normal. FESS ...

  3. Sinus Anatomy

    Science.gov (United States)

    ... Caregivers Contact ARS HOME ANATOMY Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ... Size + - Home > ANATOMY > Sinus Anatomy Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure ...

  4. 鼻内镜下额窦开放术治疗慢性额窦炎%Intranasal frontal sinusotomy under nasal en-doscope for chronic frontal sinusitis

    Institute of Scientific and Technical Information of China (English)

    沈昌德; 王文; 黄静江; 王传喜

    2013-01-01

      目的:探讨鼻内镜下以钩突上端为标志开放额窦在治疗慢性额窦炎中的应用方法。方法:总结88例慢性额窦炎在鼻内镜下以钩突上端为标志开放额窦。术前仔细阅读鼻窦CT,了解额窦、额隐窝气房发育及病变情况、钩突附着方式,术中以钩突上端为标志准确定位额窦口,清除阻塞额窦口的病变组织,使额窦引流通畅。结果:88例以钩突上端为标志均成功找到额窦开口。术后随访6~12个月,全部病例症状消失或改善,无术后严重并发症发生。结论:鼻内镜下以钩突上端为标志开放额窦是一种解剖结构易辨认、安全有效的术式,适用于大多数额窦病变。%Objective:To explore the treatment methods for chronic frontal si-nusitis by using the mark access of superior attachment of the uncinate process to the frontal sinus .Methods:Eighty-eight patients with chronic fron-tal sinusitis undergone frontal sinus surgery were included .Before procedure , nasal CT findings were examined in great detail to fully understand the struc-ture and lesion condition of the frontal sinus and frontal recess cell as well as the attachment of the uncinate process .Intranasal frontal sinusotomy was per-formed by referring to the tip attachment of the unicinate process ,with remov-al of the diseased tissues around the aperture of frontal sinus to ensure open frontal sinus drainage .Results:Opening of the frontal sinus was successfully anchored in the total 88 cases by the approaches described above .Postopera-tive follow-up from 6 to 12 months showed that all patients had recovered or had partial relief , and no serious postoperative complications occurred . Conclusion:Intranasal frontal sinusotomy under endoscope starting with the superior attachment of the uncinate process ensures easy recognition of the anatomical characteristics of the frontal sinus and safe procedure ,which may be recommendation in most lesions at

  5. Frontal sinus mini-trephination for acute sinusitis complicated by intracranial infection.

    Science.gov (United States)

    McIntosh, D L; Mahadevan, M

    2007-10-01

    Acute bacterial sinusitis is common in the pediatric population. Intracranial spread of infection is a rare but life-threatening complication of acute sinusitis. Due to the infrequent presentation of this complication, there are no well-defined management protocols for the acute sinusitis. We present three pediatric cases where children presented with intracranial sepsis, and the underlying source of infection was from the paranasal sinuses. In all cases, endoscopic sinus surgery was performed in the acute setting, with the use of frontal sinus mini-trephines playing a significant role. We describe our experience and review the available literature.

  6. 鼻内镜下手术治疗真菌性鼻-鼻窦炎60例%The Clinical Observation of the 60 cases of fungal rhinosinusitis through the endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    邵渊; 白艳霞; 赵谦

    2013-01-01

    Objective: To discuss the endoscopic sinus surgery effect of the fungal rhinosinusitis and observe the clinical treating effect. Methods: Through the retrospective analysis of the 60 fungal rhinosinusitis patients cases who undergo the nasal endoscopic surgery,to discuss the operating methods、treating effect and results of the post operation follow-up. Result:The 60 cases of the fungal rhinosinusitis patients all be fully treated,without the obvious operating complication occurred,through the follow-up for 6 months to 2 year,l case recurred. Conclusion: the edema of the nasal cavity and nasal sinus mucous membrane that lead to local drainage dysfunction keep closely relationship with the occurrence of fungal rhinosinusitis, the nasal endoscopic sinus surgery is a kind of effective method for the treatment of it. Totally clean the local fungal tissue and maintain fluent drainage after the operation are the important factor for the treatment and transition of the fungal rhinosinusitis.%目的:探讨鼻内窥镜治疗真菌性鼻-鼻窦炎手术方法及临床疗效的观察.方法:对60例接受鼻内窥镜手术治疗的真菌性鼻-鼻窦炎患者的临床资料进行回顾性分析,探讨手术方式、手术疗效及术后随访结果.结果:60例真菌性鼻-鼻窦炎患者经手术治疗均获得临床治愈,无明显手术并发症,随访6个月至2年,1例复发.结论:鼻腔鼻窦粘膜肿胀造成的局部引流障碍与真菌性鼻-鼻窦炎的发生密切相关,鼻内镜手术是治疗真菌性鼻-鼻窦炎的有效方法,彻底清除病变及术后鼻窦引流通畅是影响疗效及转归的重要因素.

  7. Flexible LMA在鼻内镜手术中应用的气道安全性%Airway safety of application of flexible laryngeal mask airway in endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    马佳佳; 李天佐

    2011-01-01

    Objective: To investigate the safety of application of flexible laryngeal mask airway (Flexible LMA) in endoscop -ic sinus surgery (ESS) compared with endotracheal intubation. Methods: 60 adult patients selected for EES were randomly divided into group F and group T, with 30 patients for each group. Observation items included the impermeability of the Flexible LMA, blood staining conditions of the laryngeal mask after extraction and ventilation effectiveness, respiratory ca -pacity of the pressure loopy and the difficulty level of insertion between the two groups. Results: Impermeability of the Flexible LMA after insertion and before extraction was reliable. Auscultation showed clear neck breath sounds. One case of ventral blood stain occurred after extraction of the laryngeal mask. There was no significant difference between the two groups as to the ventilation effectiveness (P>0.05). The airway peak pressure of the group F was lower than that of the group T (P0.05). The insertion time of the group F was shorter than that of the group T (P=0.017). Conclusion: Compared with endotracheal intubation, the application of Flexible LMA in endoscopic sinus surgery is safe and practicable.%目的:探讨与气管插管相比,Flexible LMA(flexible laryngeal mask airway)在全麻下鼻内镜手术(endoscope sinus surgery,ESS)中的应用的安全性.方法:选取择期行ESS手术的成年患者60例,将其随机分为F组和T组,每组各30例.观察Flexible LMA的密闭性,拔出喉罩后罩体血染情况,比较两组通气效果、呼吸容量环路及插入难易程度.结果:Flexible LMA漏气压力值在插入后和拔出前均较满意,颈部呼吸音听诊均清晰,拔出喉罩腹侧血染为1例;两组通气效果比较差异无统计学意义(P>0.05),F组各时点气道峰压均低于T组(均P<0.05);呼吸容量环路比较差异无统计学意义(P>0.05);F组置入时间低于T组(P=0.017).结论:Flexible LMA与气管插管相比在ESS术中的应用是安全可行的.

  8. 鼻内镜术后病情迁延的细菌学分析%Bacteriological analysis of persistent rhinosinusitis after endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    代保强; 王全桂

    2012-01-01

    目的:探讨慢性鼻-鼻窦炎(CRS)鼻内镜术后迁延不愈者鼻腔分泌物的细菌学特征.方法:选取单纯鼻中隔偏曲患者20例(对照组),取其中鼻道分泌物;选取首次接受鼻内镜手术的CRS患者30例(手术组),术中取中鼻道分泌物;取FESS术后随访3个月以上未达治愈标准的患者20例(迁延组),在鼻内镜下取中鼻道分泌物,分别做细菌培养和药物敏感试验,3组结果进行比较分析.结果:对照组检出细菌13株,手术组检出15株,迁延组检出15株,其检出阳性率差异无统计学意义;迁延组G-菌检出率明显高于对照组和手术组;对常用抗生素耐药的菌株比例迁延组显著高于手术组.结论:需氧菌可存在于正常鼻腔内;CRS术后迁延不愈者,G-杆菌的感染和细菌的耐药性明显增加.因此,强调要合理应用抗生素,对术后迁延性鼻窦炎的抗生素治疗,应建立在细菌培养和药敏试验的基础上.%Objective:To investigate the bacterial characteristics of persistent rhinosinusitis after functional endoscopic sinus surgery(FESS). Method: Twenty patients with nasal septum deviation, 30 patients with chronic rh-inosinusitis(CRS) and 20 patients with persistent rhinosinusitis, were selected to take discharges from middle me-atus during the operation. Bacteria culture and drug susceptibility of the discharges were compared betweent three groups. Result:There were 13,15 and 15 isolates detected in nasal septum deviation group, CRS group and persis-tent rhinosinusitis group. There was no significant difference among the three groups at the detection rate of Gram-positive bacteria. But there was significant difference between the persistent rhinosinusitis group and the oth-er two groups at the detection rate of Gram-negative bacteria. The detection rate of antibiotic-resistant bacteria were significantly higher in persistent rhinosinusitis group than in CRS group. Conclusion) Aerobic bacteria can live in nasal

  9. Mathematical modelling in the computer-aided process planning

    Science.gov (United States)

    Mitin, S.; Bochkarev, P.

    2016-04-01

    This paper presents new approaches to organization of manufacturing preparation and mathematical models related to development of the computer-aided multi product process planning (CAMPP) system. CAMPP system has some peculiarities compared to the existing computer-aided process planning (CAPP) systems: fully formalized developing of the machining operations; a capacity to create and to formalize the interrelationships among design, process planning and process implementation; procedures for consideration of the real manufacturing conditions. The paper describes the structure of the CAMPP system and shows the mathematical models and methods to formalize the design procedures.

  10. 波及上颌窦的大型颌骨囊肿的治疗及临床效果%Piezosurgery and Endoscopic Assistance in the Treatment of Jaw Cysts Involving the Maxillary Sinus

    Institute of Scientific and Technical Information of China (English)

    王维; 池宇峰; 谭锡涛; 汪晓霞; 谢彬

    2016-01-01

    Objective: To discuss and compare the effects of piezosurgery and endoscopic assistance in the treatment of large jaw cysts involving the maxillary sinus. Methods: 72 patients of large jaw cyst with infringement of maxillary sinus from July 2007 to March 2015 were divided into two groups and retrospectively reviewed. Group A (n=36), the piezo-surgery and nasal endoscopic measures were collectively used. The jaw cysts were completely removed with preservation of the normal mucosa of maxillary sinus and contour of maxillary bone. Group B (n=36) a part of maxillary bone was cleaned by osteotome and bone forceps. The cyst wall was curetted, then the patients were underwent Caldwell-Luc opera-tion. After a follow-up of 3-72 months, the postoperative complications were recorded for assessment. Chi-square test and SPSS 13.0 software package were used for statistical analysis. Results: The incidence of postoperative complications such as maxillary sinus fistula, facial deformity, and nasal obstruction in group A were significantly lower than that in group B (P<0.05). The recovery of facial contour and masticatory function were better in group A patients. Conclusion: Piezo-surgery and nasal endoscopic assistance in the treatment of large jaw cysts involving the maxillary sinus can effectively de-crease the postoperative complications.%目的:探讨侵犯上颌窦的大型颌骨囊肿的治疗和临床效果.方法:回顾2007-07—2015-03期间,在本院治疗的72例侵犯上颌窦的颌骨囊肿患者.A组(n=36)术中联合用超声骨刀和鼻内镜,彻底清除病变组织,保存正常窦内黏膜及骨骼外形;B组(n=36)术中用骨凿、咬骨钳去除骨壁,摘除囊壁组织后用刮匙搔刮囊腔及行上颌窦根治术.术后随访观察3~72个月,对术后并发症进行对比观察和统计学分析.采用SPSS13.0软件包对数据进行χ2检验.结果:A组患者在上颌窦瘘、面部畸形、鼻通气功能方面,术后并发症发生率显著低于B组(P<0

  11. Sphenoid sinus mucocele

    Science.gov (United States)

    Bahgat, Mohammed; Bahgat, Yassin; Bahgat, Ahmed

    2012-01-01

    The authors present their experience of managing an interesting case of a 65-year-old woman who presented to their clinic with 1-month history of persistent deep-seated headache. The patient sought medical advice in neurology and ophthalmology clinics before being referred to the ear, nose and throat clinic. CT imaging revealed isolated opacification and expansion of both sphenoid sinuses with bony continuity along the periphery of the sinuses features consistent with mucocele. MRI was needed to fully evaluate the extension of the lesion. The lesion was diagnosed as bilateral sphenoid sinuses mucoceles. Transnasal endoscopic drainage of the sphenoid mucoceles leads to gradual improvement of the symptoms. We discuss the clinical presentation, diagnosis and treatment of this case as well as a review of the literature. PMID:23093506

  12. Sinus surgery postpones chronic gram-negative lung infection

    DEFF Research Database (Denmark)

    Alanin, M C; Aanaes, K; Høiby, N

    2016-01-01

    Background: In patients with cystic fibrosis (CF) the sinuses are a bacterial reservoir for Gram-negative bacteria (GNB). From the sinuses the GNB can repeatedly migrate to the lungs. In a one-year follow-up study, endoscopic sinus surgery (ESS) with adjuvant therapy reduced the frequency...

  13. A critically appraised topic review of computer-aided design/computer-aided machining of removable partial denture frameworks.

    Science.gov (United States)

    Lang, Lisa A; Tulunoglu, Ibrahim

    2014-01-01

    A critically appraised topic (CAT) review is presented about the use of computer-aided design (CAD)/computer-aided machining (CAM) removable partial denture (RPD) frameworks. A systematic search of the literature supporting CAD/CAM RPD systems revealed no randomized clinical trials, hence the CAT review was performed. A PubMed search yielded 9 articles meeting the inclusion criteria. Each article was characterized by study design and level of evidence. No clinical outcomes research has been published on the use of CAD/CAM RPDs. Low levels of evidence were found in the available literature. Clinical research studies are needed to determine the efficacy of this treatment modality.

  14. [Clinical analysis of nasal sinus mucocele with eye symptoms as main manifestation: 3 cases report].

    Science.gov (United States)

    Gu Qingjia; Li Jingxian; Fan Jiangang

    2015-04-01

    Endoscopic sinus surgery is effective to nasal sinus mucocele with eye symptoms as main manifestation. It is very importment to raise the awareness of the disease and to prompt imaging examination. Three cases were reviewed. One mucocele was found in the frontal sinus ethmoid sinus,1 in the fronto-ethmoid sinus and 1 in the spheno-ethmoid sinus. All cases were preoperatively diagnosed by CT, MRI or intranasal endoscopy. Nasal sinus mucocele with eye symptoms as main manifestation should be early diagnosed. Endoscopic sinus surgery is a safe and effective method for the treatment of nasal sinus mucocele,and could be the primary choice for it. All cases were treated by nasal endoscopic sinus surgery. The majority of symptoms, such as exophthalmos, epiphora and diplopia, disappeared in all patients. However, vision recovery was observed only in some patients.

  15. Helping Alleviate Statistical Anxiety with Computer Aided Statistical Classes

    Science.gov (United States)

    Stickels, John W.; Dobbs, Rhonda R.

    2007-01-01

    This study, Helping Alleviate Statistical Anxiety with Computer Aided Statistics Classes, investigated whether undergraduate students' anxiety about statistics changed when statistics is taught using computers compared to the traditional method. Two groups of students were questioned concerning their anxiety about statistics. One group was taught…

  16. Computer-aided modelling template: Concept and application

    DEFF Research Database (Denmark)

    Fedorova, Marina; Sin, Gürkan; Gani, Rafiqul

    2015-01-01

    decomposition technique which identifies generic steps and workflow involved, the computer-aided template concept has been developed. This concept is implemented as a software tool, which provides a user-friendly interface for following the workflow steps and guidance through the steps providing additional...

  17. Computer-Aided Template for Model Reuse, Development and Maintenance

    DEFF Research Database (Denmark)

    Fedorova, Marina; Sin, Gürkan; Gani, Rafiqul

    2014-01-01

    A template-based approach for model development is presented in this work. Based on a model decomposition technique, the computer-aided template concept has been developed. This concept is implemented as a software tool , which provides a user-friendly interface for following the workflow steps, ...

  18. The Journal of Computer- Aided Molecular Design: a bibliometric note

    Science.gov (United States)

    Willett, Peter

    2012-01-01

    Summarizes the articles in, and the citations to, volumes 2-24 of the Journal of Computer- Aided Molecular Design. The citations to the journal come from almost 2000 different sources that span a very wide range of academic subjects, with the most heavily cited articles being descriptions of software systems and of computational methods.

  19. De novo computer-aided design of novel antiviral agents.

    Science.gov (United States)

    Massarotti, Alberto; Coluccia, Antonio; Sorba, Giovanni; Silvestri, Romano; Brancale, Andrea

    2012-01-01

    Computer-aided drug design techniques have become an integral part of the drug discovery process. In particular, de novo methodologies can be useful to identify putative ligands for a specific target relying only on the structural information of the target itself. Here we discuss the basic de novo approaches available and their application in antiviral drug design.:

  20. A Computer Aided System for Simulating Weld Metal Solidification Crack

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A computer-aided system for simulating weld solidification crack has been developed by which a welding engineer can carry out the welding solidification crack simulation on the basis of a commercial finite element analysis software package. Its main functions include calculating the heat generations of the moving arc, mesh generation, calculating stress-strain distributions with element rebirth technique.

  1. Odontogenic maxillary sinusitis: a review.

    Science.gov (United States)

    Simuntis, Regimantas; Kubilius, Ričardas; Vaitkus, Saulius

    2014-01-01

    Maxillary sinusitis of odontogenic origin is a well-known condition in both the dental and otolaryngology communities. It occurs when the Schneiderian membrane is violated by conditions arising from dentoalveolar unit. This type of sinusitis differs in its pathophysiology, microbiology, diagnostics and management from sinusitis of other causes, therefore, failure to accurately identify a dental cause in these patients usually lead to persistent symptomatology and failure of medical and surgical therapies directed toward sinusitis. Unilateral recalcitrant disease associated with foul smelling drainage is a most common feature of odontogenic sinusitis. Also, high-resolution CT scans and cone-beam volumetric computed tomography can assist in identifying dental disease. Sometimes dental treatment alone is adequate to resolve the odontogenic sinusitis and sometimes concomitant or subsequent functional endoscopic sinus surgery or Caldwell-Luc operation is required. The aim of this article is to give a review of the most common causes, symptoms, diagnostic and treatment methods of odontogenic maxillary sinusitis. Search on Cochrane Library, PubMed and Science Direct data bases by key words resulted in 35 articles which met our criteria. It can be concluded that the incidence of odontogenic sinusitis is likely underreported in the available literature.

  2. Nursing of endoscopic sinus surgery in the treatment of children with chronic rhinosinusitis%鼻内镜手术治疗儿童慢性鼻窦炎的护理

    Institute of Scientific and Technical Information of China (English)

    褚薇薇

    2012-01-01

    目的 探讨鼻内镜手术治疗儿童慢性鼻窦炎的观察和护理.方法 对54例14岁以下慢性鼻窦炎患儿行功能性鼻内窥镜手术后术前、术后一般护理、术腔护理及并发症护理等环节进行回顾性分析.结果 54例儿童慢性鼻窦炎有效51例,有效率94.4%,无颅内及眼部并发症出现.随访1年以上,采用系统护理方法,能促进鼻腔鼻窦黏膜生理功能恢复,减少和预防并发症发生,与手术本身同样重要.结论 重视和加强术后一般护理及术腔护理,定期随访,可明显提高儿童慢性鼻窦炎治愈率.%Objective To explore the observation and nursing of endoscopic sinus surgery in the treatment of children with chronic rhinosinusitis. Methods Fifty - four children under 14 years old with chronic rhinosinusitis were included in the study and they received functional endoscopic sinus surgery. Preoperative nursing,postoperative nursing,surgical cavity nursing and nursing of complications were retrospectively reviewed and analyzed. Results In all 54 cases,51 cases were effectively cured with a cure rate of 94.4% ,and there were no ocular or intracranial complications. The results of over one - year follow - up showed that systematic nursing promoted the restoration of physiological functions of nasal cavity and paranasal sinus mucosa,and it also reduced and prevented the complications,which was as important as the surgery itself. Conclusion Emphasis and reinforcement of postoperative nursing and surgical cavity nursing as well as regular follow -up can improve the cure rate of chronic rhinosinusitis in children.

  3. The effects on morphology of middle turbinate and olfaction after endoscopic sinus surgery and conventional technique in sinus surgery%内窥镜鼻窦手术与传统鼻窦手术对中鼻甲及嗅觉的影响

    Institute of Scientific and Technical Information of China (English)

    许春华; 钟彦; 宋若会

    2001-01-01

    目的:观察内窥镜鼻腔、鼻窦手术与传统鼻腔、鼻窦手术在慢性鼻窦炎、鼻息肉(Ⅰ型2期,Ⅱ型2期)中的手术疗效对中鼻甲形态及嗅觉的影响。方法:对1997年9月~1999年9月间参加该项研究并随访半年以上的二组病例85例(163侧),经冠状位鼻窦CT扫描,术前、术后鼻内窥镜检查及嗅觉测试。二组分别施行内窥镜鼻腔、鼻窦手术及传统鼻腔、鼻窦手术,对中鼻甲病变采取完整保留和部分切除二类方式。结果:经内窥镜鼻腔、鼻窦手术,随访半年以上的52例(101侧)患者鼻窦炎治愈、好转、无效率分别是64.4%、29.7%、5.9%;相应中鼻甲恢复正常率分别是63.1%、30.0%、0.0%;嗅觉恢复正常率分别是66.2%、36.7%、0.0%。33例(62侧)经传统鼻腔、鼻窦手术患者鼻窦炎治愈、好转、无效率分别是30.6%、48.4%、21.0%;相应中鼻甲恢复正常率分别是47.4%、3.3%、0.0%;嗅觉恢复正常率分别是63.2%、23.3%、0.0%。结论:内窥镜鼻窦手术较传统鼻窦手术更有效地解决窦口鼻道复合体病变,从而提高Ⅰ型、Ⅱ型鼻窦炎治愈率。本研究表明中鼻甲形态的转归,嗅觉恢复与鼻窦炎治愈率有明显的相关性。%Objective: To observe the effects on morphology of middle turbinate and olfaction in trasnasal endoscopic sinus surgery and conventional technique in surgery in chronic sinusitis and nasal polyps (stage Ⅰ,Ⅱ)。 Methods: Two groups patients (85 cases, 163 sites) from September 1979 to September 1999 were examined by coronal CT scans of sinus, nasal endoscopy and olfctory test preoperative and postoperative. Of these patients, 52 cases (101 sites) were operated by transnasal endoscopic sinus surgery, 33 cases (62 sites) were operated by conventional technique in surgery respectively. Management of middle turbinate was divided into reserving and resecting two way. Results: In group of endoscopic sinus surgeries (52

  4. Effect of Azithromycin on NF-kBp65 and IL-8 in nasal mucosa of chronic sinusitis after endoscopic sinus surgery%阿奇霉素对慢性鼻-鼻窦炎患者术腔黏膜中NF-kBp65IL-8表达的影响

    Institute of Scientific and Technical Information of China (English)

    白永; 李娜; 赵慎林; 张旻

    2012-01-01

    Objective To observe the effect of azithromycin on expressions of NF-kBp65 and IL-8 in nasal mucosa of chronic sinusitis after endoscopic sinus surgery. Methods 45 patients with chronic sinusitis and/or nasal polyps who were treated with endoscopic surgery 2 weeks previously were divided into 3 groups: 15 patients treated with local glucocorticoid as the control group, 15 patients were added with cephalosporin(500 mg, once a day) as another control group, others were added with Azithromycin(500 mg, once a day) as the experimental group. The PV-6000 immuno-histochemical method was applied to explore expressions of NF-kBp65 and IL-8 in nasal mucosa before and after 3-week medical therapy while counting the quantity of positive cells. Results Chronic inflammation was observed in nasal mucosa after endoscopic sinus surgery by HE staining. There were many inflammatory cells such as neutrophil cells and eosinophil cells under the mucosa] epithelium, and the neutrophil cells were the key cells. Expression of NF-kBp65 was positive in the cytoplasm and some nuclei of the mucosal epithelia and the inflammatory cells in nasal mucosa. Expression of IL-8 was positive in the cytoplasm of the mucosal epithelia and inflammatory cells in nasal mucosa. Expressions of NF-kBp65 and IL-8 were significantly reduced in the mucosal epithelia and inflammatory cells of nasal mucosa after 3 weeks medical treatment compared with that of pre-treatment in the three groups (P 0. 05).Conclusion Azithromycin in combination with local glucocorticoid is better than glucocorticoid to inhibit expressions of NF-kBp65 and IL-8 in mucosal epithelia and inflammatory cells in nasal mucosa of chronic sinusitis and/or nasal polyps after endoscopic sinus surgery. It is an effective method to cure chronic inflammation of nasal mucosa in the nasal cavity after endoscopic sinus surgery.%目的 观察阿奇霉素对慢性鼻-鼻窦炎患者术腔黏膜中NF-kBp65、IL-8表达的影响,探讨阿奇霉素治疗术

  5. Computer-Aided Design and Computer-Aided Manufacturing Hydroxyapatite/Epoxide Acrylate Maleic Compound Construction for Craniomaxillofacial Bone Defects.

    Science.gov (United States)

    Zhang, Lei; Shen, Shunyao; Yu, Hongbo; Shen, Steve Guofang; Wang, Xudong

    2015-07-01

    The aim of this study was to investigate the use of computer-aided design and computer-aided manufacturing hydroxyapatite (HA)/epoxide acrylate maleic (EAM) compound construction artificial implants for craniomaxillofacial bone defects. Computed tomography, computer-aided design/computer-aided manufacturing and three-dimensional reconstruction, as well as rapid prototyping were performed in 12 patients between 2008 and 2013. The customized HA/EAM compound artificial implants were manufactured through selective laser sintering using a rapid prototyping machine into the exact geometric shapes of the defect. The HA/EAM compound artificial implants were then implanted during surgical reconstruction. Color-coded superimpositions demonstrated the discrepancy between the virtual plan and achieved results using Geomagic Studio. As a result, the HA/EAM compound artificial bone implants were perfectly matched with the facial areas that needed reconstruction. The postoperative aesthetic and functional results were satisfactory. The color-coded superimpositions demonstrated good consistency between the virtual plan and achieved results. The three-dimensional maximum deviation is 2.12 ± 0.65  mm and the three-dimensional mean deviation is 0.27 ± 0.07  mm. No facial nerve weakness or pain was observed at the follow-up examinations. Only 1 implant had to be removed 2 months after the surgery owing to severe local infection. No other complication was noted during the follow-up period. In conclusion, computer-aided, individually fabricated HA/EAM compound construction artificial implant was a good craniomaxillofacial surgical technique that yielded improved aesthetic results and functional recovery after reconstruction.

  6. Detection of longitudinal ulcer using roughness value for computer aided diagnosis of Crohn's disease

    Science.gov (United States)

    Oda, Masahiro; Kitasaka, Takayuki; Furukawa, Kazuhiro; Watanabe, Osamu; Ando, Takafumi; Goto, Hidemi; Mori, Kensaku

    2011-03-01

    The purpose of this paper is to present a new method to detect ulcers, which is one of the symptoms of Crohn's disease, from CT images. Crohn's disease is an inflammatory disease of the digestive tract. Crohn's disease commonly affects the small intestine. An optical or a capsule endoscope is used for small intestine examinations. However, these endoscopes cannot pass through intestinal stenosis parts in some cases. A CT image based diagnosis allows a physician to observe whole intestine even if intestinal stenosis exists. However, because of the complicated shape of the small and large intestines, understanding of shapes of the intestines and lesion positions are difficult in the CT image based diagnosis. Computer-aided diagnosis system for Crohn's disease having automated lesion detection is required for efficient diagnosis. We propose an automated method to detect ulcers from CT images. Longitudinal ulcers make rough surface of the small and large intestinal wall. The rough surface consists of combination of convex and concave parts on the intestinal wall. We detect convex and concave parts on the intestinal wall by a blob and an inverse-blob structure enhancement filters. A lot of convex and concave parts concentrate on roughed parts. We introduce a roughness value to differentiate convex and concave parts concentrated on the roughed parts from the other on the intestinal wall. The roughness value effectively reduces false positives of ulcer detection. Experimental results showed that the proposed method can detect convex and concave parts on the ulcers.

  7. 鼻内镜下鼻泪管前径路和后径路切除上颌窦良性病变%Endoscopic maxillary sinus surgery through anterior or posterior nasolacrimal duct approach

    Institute of Scientific and Technical Information of China (English)

    宋西成; 张庆泉; 孙岩; 张华; 陈秀梅; 王强; 王丽; 柳忠禄; 董蕾; 张天振

    2011-01-01

    通畅无闭锁.结论鼻内镜下鼻泪管前、后径路上颌窦手术可以减小创伤,充分暴露窦腔视野,并为术后内镜复查和复发后的处理提供了视窗;保留下鼻甲避免了鼻腔外侧壁去除过多而导致的术后干燥、结痂、头痛等并发症.%Objective To explore the feasibility and effectiveness of the approaches and methodology of the endoscopic surgery for maxillary sinus lesions through the medial wall of the maxillary sinus.Methods From Jun.2003 to Aug.2010,endoscopic surgery through anterior or posterior nasolacrimal duct approaches to remove maxillary sinus lesions were conducted in 139 patients.Among them there were 43 cases with inverted papilloma,63 cases with fungal maxillary sinusitis,28 cases with maxillary sinus cyst,3 cases with hemorrhagic necrotic polyps,and 2 cases with osteomas.All patients underwent preoperative CT scans,and patients with inverted papillomas also had MRI tests.Anterior-nasolacrimal canal paths included 3 ways:pyriform aperture,lacrimal bone recess (dissecting nasolacrimal duct or not were 2 subtypes),pyriform aperture-nasolacrimal duct approaches,and 97 patients were treated.Posterior-nasal lacrimal duct paths were also divided into 3 subtypes:the inferior turbinate flip flap,double pedicle inferior turbinate,single pedicle inferior turbinate,and 42 patients were treated.The postoperative effects were observed.Results All lesions were completely removed under endoscope,the nasolacrimal ducts and inferior turbinates were protected,no nasal lacrimal duct injury and inferior turbinate necrosis were found.Postoperative nasal congestion,headache,swelling discomfort,strange odor,dental pain and numbness and other symptoms gradually disappeared.Nine patients felt nasal dryness,and after nasal washing for about 1 month,the symptom gradually disappeared.Patients were followed up for 6 months to 79 months.In case of osteoma,and hemorrhagic and necrotic polyps,no recurrences were found

  8. Pediatric Sinusitis

    Science.gov (United States)

    ... requests or policy questions to our media and public relations staff at newsroom@entnet.org . Your child’s sinuses ... viral upper respiratory infections in children, and the role of such medications for treatment of sinusitis is ...

  9. Adult Sinusitis

    Science.gov (United States)

    ... Epiphora (Excessive Tearing) Disclosure Statement Printer Friendly Adult Sinusitis Berrylin J. Ferguson, MD Sarah K. Wise, MD ... determine the best treatment for your condition. COMMON SINUSITIS SYMPTOMS Nasal obstruction or nasal congestion Thick & discolored ...

  10. [Odontogenic maxillary sinusitis caused by dental restoration].

    Science.gov (United States)

    Sato, Kiminori

    2014-06-01

    We report herein on 5 patients with odontogenic maxillary sinusitis caused by a dental restoration (caries cutting, cavity preparation, inlay restoration). Odontogenic maxillary sinusitis was noted following dental restoration. Even though the pulp cavity and dental pulp were intact, the odontogenic maxillary sinusitis occurred caused by an apical lesion. Infection by way of the dentinal tubules was suggested to be a cause of the pathophysiology. Endoscopic sinus surgery was indicated in patients with intractable odontogenic maxillary sinusitis caused by the dental restoration. Cone-beam x-ray CT was useful for the accurate diagnosis of odontogenic maxillary sinusitis caused by a dental restoration. Physicians should thus be aware of the possibility that a tooth, which has undergone dental restoration, may cause odontogenic maxillary sinusitis.

  11. Allergic fungal sinusitis causing nasolacrimal duct obstruction.

    Science.gov (United States)

    Kim, Charles; Kacker, Ashutosh; Chee, Ru-Ik; Lelli, Gary J

    2013-04-01

    Allergic fungal sinusitis is thought to represent a chronic autoimmune reaction directed against fungal elements within the sinuses, and is commonly seen in individuals with a history of chronic sinusitis that is refractory to medical therapy. The authors present a case of allergic fungal sinusitis involving the lacrimal drainage system. A 54-year-old woman initially presented with recurrent erythema and induration of the left nasolacrimal sac due to dacryocystitis, which was unresponsive to treatment with topical and systemic antibiotics. Radiological evaluation demonstrated the presence of multiple soft tissue masses along the medial canthi. During subsequent endoscopic dacryocystorhinostomy, significant amounts of allergic mucin were found within the sinuses and marked eosinophilia was present within tissue obtained from the lacrimal sac, findings highly suggestive of allergic fungal sinusitis. A diagnosis of allergic fungal sinusitis should be considered in patients presenting with epiphora in the appropriate clinical context. However, involvement of the lacrimal drainage system is an exceedingly unusual presentation.

  12. Late recovery from foreign body sinusitis after maxillary sinus floor augmentation

    Science.gov (United States)

    Felisati, Giovanni; Saibene, Alberto Maria; Lenzi, Riccardo; Pipolo, Carlotta

    2012-01-01

    A 55-year-old male patient was referred to our clinic with signs and symptoms of recurring sinusitis after a right maxillary sinus floor augmentation for implantological purposes. Investigations showed an antibiotic-resistant ethmoidomaxillary sinusitis resulting from bone graft infection and displacement of previously inserted xenograft material into the maxillary sinus. The patient thus underwent a surgical procedure combining nasal endoscopy and oral surgery in order to remove the infected graft and restore sinusal drainage. The procedure was apparently successful but sinusitis relapsed after surgery and persisted despite 2 weeks of antibiotic therapy and local medications. A CT scan showed persistence of grafting fragments in the maxillary sinus. A new surgical procedure was scheduled while a more accurate endoscopic local medication was performed. Six hours after the treatment, the patient spontaneously expelled the fragments and promptly recovered. The patient successfully underwent another maxillary sinus floor augmentation procedure 6 months later. PMID:23234824

  13. Late recovery from foreign body sinusitis after maxillary sinus floor augmentation.

    Science.gov (United States)

    Felisati, Giovanni; Saibene, Alberto Maria; Lenzi, Riccardo; Pipolo, Carlotta

    2012-12-12

    A 55-year-old male patient was referred to our clinic with signs and symptoms of recurring sinusitis after a right maxillary sinus floor augmentation for implantological purposes. Investigations showed an antibiotic-resistant ethmoidomaxillary sinusitis resulting from bone graft infection and displacement of previously inserted xenograft material into the maxillary sinus. The patient thus underwent a surgical procedure combining nasal endoscopy and oral surgery in order to remove the infected graft and restore sinusal drainage. The procedure was apparently successful but sinusitis relapsed after surgery and persisted despite 2 weeks of antibiotic therapy and local medications. A CT scan showed persistence of grafting fragments in the maxillary sinus. A new surgical procedure was scheduled while a more accurate endoscopic local medication was performed. Six hours after the treatment, the patient spontaneously expelled the fragments and promptly recovered. The patient successfully underwent another maxillary sinus floor augmentation procedure 6 months later.

  14. Cranialization of the frontal sinus-the final remedy for refractory chronic frontal sinusitis

    NARCIS (Netherlands)

    van Dijk, J. Marc C.; Wagemakers, Michiel; Korsten-Meijer, Astrid G. W.; Buiter, C. T. Kees; van der Laan, Bernard F. A. M.; Mooij, Jan Jakob A.

    2012-01-01

    Object. Chronic sinusitis can be a debilitating disease with significant impact on quality of life. Frontal sinusitis has a relatively low prevalence, but complications can be severe due to its anatomical location. After failure of conservative measures, typically endoscopic procedures are performed

  15. [Sinus lift and dental implantation after endosurgical treatment of odontogenic maxillary sinusitis].

    Science.gov (United States)

    Sysoliatin, S P; Sysoliatin, P G; Palkina, M O; Solop, M V

    2013-01-01

    The long-term results of dental implant placement in patients with the history of odontogenic maxillary sinusitis are assessed in retrospective study. Maxillary sinusotomy and endoscopic surgery procedures are compared in regard to complications risks after subsequent sinus lift and dental implantation, the latter proving to be method of choice in such cases.

  16. Cranialization of the frontal sinus-the final remedy for refractory chronic frontal sinusitis

    NARCIS (Netherlands)

    van Dijk, J. Marc C.; Wagemakers, Michiel; Korsten-Meijer, Astrid G. W.; Buiter, C. T. Kees; van der Laan, Bernard F. A. M.; Mooij, Jan Jakob A.

    2012-01-01

    Object. Chronic sinusitis can be a debilitating disease with significant impact on quality of life. Frontal sinusitis has a relatively low prevalence, but complications can be severe due to its anatomical location. After failure of conservative measures, typically endoscopic procedures are performed

  17. Cranialization of the frontal sinus-the final remedy for refractory chronic frontal sinusitis

    NARCIS (Netherlands)

    van Dijk, J. Marc C.; Wagemakers, Michiel; Korsten-Meijer, Astrid G. W.; Buiter, C. T. Kees; van der Laan, Bernard F. A. M.; Mooij, Jan Jakob A.

    Object. Chronic sinusitis can be a debilitating disease with significant impact on quality of life. Frontal sinusitis has a relatively low prevalence, but complications can be severe due to its anatomical location. After failure of conservative measures, typically endoscopic procedures are performed

  18. Computer-Aided Modeling of Lipid Processing Technology

    DEFF Research Database (Denmark)

    Diaz Tovar, Carlos Axel

    2011-01-01

    are widely used for design, analysis, and optimization of processes in the chemical and petrochemical industries. These computer-aided tools have helped the chemical industry to evolve beyond commodities toward specialty chemicals and ‘consumer oriented chemicals based products’. Unfortunately...... this is not the case for the edible oil and biodiesel industries. The oleochemical industry lags behind the chemical industry in terms of thermophysical property modeling and development of computational tools suitable for the design/analysis, and optimization of lipid-related processes. The aim of this work has been...... increase along with growing interest in biofuels, the oleochemical industry faces in the upcoming years major challenges in terms of design and development of better products and more sustainable processes to make them. Computer-aided methods and tools for process synthesis, modeling and simulation...

  19. Computer Aided Design System for Developing Musical Fountain Programs

    Institute of Scientific and Technical Information of China (English)

    刘丹; 张乃尧; 朱汉城

    2003-01-01

    A computer aided design system for developing musical fountain programs was developed with multiple functions such as intelligent design, 3-D animation, manual modification and synchronized motion to make the development process more efficient. The system first analyzed the music form and sentiment using many basic features of the music to select a basic fountain program. Then, this program is simulated with 3-D animation and modified manually to achieve the desired results. Finally, the program is transformed to a computer control program to control the musical fountain in time with the music. A prototype system for the musical fountain was also developed. It was tested with many styles of music and users were quite satisfied with its performance. By integrating various functions, the proposed computer aided design system for developing musical fountain programs greatly simplified the design of the musical fountain programs.

  20. Method of Computer-aided Instruction in Situation Control Systems

    Directory of Open Access Journals (Sweden)

    Anatoliy O. Kargin

    2013-01-01

    Full Text Available The article considers the problem of computer-aided instruction in context-chain motivated situation control system of the complex technical system behavior. The conceptual and formal models of situation control with practical instruction are considered. Acquisition of new behavior knowledge is presented as structural changes in system memory in the form of situational agent set. Model and method of computer-aided instruction represent formalization, based on the nondistinct theories by physiologists and cognitive psychologists.The formal instruction model describes situation and reaction formation and dependence on different parameters, effecting education, such as the reinforcement value, time between the stimulus, action and the reinforcement. The change of the contextual link between situational elements when using is formalized.The examples and results of computer instruction experiments of the robot device “LEGO MINDSTORMS NXT”, equipped with ultrasonic distance, touch, light sensors.

  1. Microstereolithography-based computer-aided manufacturing for tissue engineering.

    Science.gov (United States)

    Cho, Dong-Woo; Kang, Hyun-Wook

    2012-01-01

    Various solid freeform fabrication technologies have been introduced for constructing three-dimensional (3-D) freeform structures. Of these, microstereolithography (MSTL) technology performs the best in 3-D space because it not only has high resolution, but also fast fabrication speed. Using this technology, 3-D structures with mesoscale size and microscale resolution are achievable. Many researchers have been trying to apply this technology to tissue engineering to construct medically applicable scaffolds, which require a 3-D shape that fits a defect with a mesoscale size and microscale inner architecture for efficient regeneration of artificial tissue. This chapter introduces the principles of MSTL technology and representative systems. It includes fabrication and computer-aided design/computer-aided manufacturing (CAD/CAM) processes to show the automation process by which measurements from medical images are used to fabricate the required 3-D shape. Then, various tissue engineering applications based on MSTL are summarized.

  2. Computer-Aided Numerical Inversion of Laplace Transform

    OpenAIRE

    Umesh Kumar

    2000-01-01

    This paper explores the technique for the computer aided numerical inversion of Laplace transform. The inversion technique is based on the properties of a family of three parameter exponential probability density functions. The only limitation in the technique is the word length of the computer being used. The Laplace transform has been used extensively in the frequency domain solution of linear, lumped time invariant networks but its application to the time domain has been limited, mainly be...

  3. Information and computer-aided system for structural materials

    Energy Technology Data Exchange (ETDEWEB)

    Nekrashevitch, Yu.G.; Nizametdinov, Sh.U.; Polkovnikov, A.V.; Rumjantzev, V.P.; Surina, O.N. (Engineering Physics Inst., Moscow (Russia)); Kalinin, G.M.; Sidorenkov, A.V.; Strebkov, Yu.S. (Research and Development Inst. of Power Engineering, Moscow (Russia))

    1992-09-01

    An information and computer-aided system for structural materials data has been developed to provide data for the fusion and fission reactor system design. It is designed for designers, industrial engineers, and material science specialists and provides a friendly interface in an interactive mode. The database for structural materials contains the master files: Chemical composition, physical, mechanical, corrosion, technological properties, regulatory and technical documentation. The system is implemented on a PC/AT running the PS /2 operating system. (orig.).

  4. Computer-aided design and computer science technology

    Science.gov (United States)

    Fulton, R. E.; Voigt, S. J.

    1976-01-01

    A description is presented of computer-aided design requirements and the resulting computer science advances needed to support aerospace design. The aerospace design environment is examined, taking into account problems of data handling and aspects of computer hardware and software. The interactive terminal is normally the primary interface between the computer system and the engineering designer. Attention is given to user aids, interactive design, interactive computations, the characteristics of design information, data management requirements, hardware advancements, and computer science developments.

  5. An Integrated Computer-Aided Approach for Environmental Studies

    DEFF Research Database (Denmark)

    Gani, Rafiqul; Chen, Fei; Jaksland, Cecilia;

    1997-01-01

    A general framework for an integrated computer-aided approach to solve process design, control, and environmental problems simultaneously is presented. Physicochemical properties and their relationships to the molecular structure play an important role in the proposed integrated approach. The scope...... and applicability of the integrated approach is highlighted through examples involving estimation of properties and environmental pollution prevention. The importance of mixture effects on some environmentally important properties is also demonstrated....

  6. Contributions on Computer Aided Manufacturing of Drill-Jig Bushings

    Directory of Open Access Journals (Sweden)

    Vasile Cojocaru

    2009-01-01

    Full Text Available The paper presents the steps for computer aided manufacturing (CAMof the bushings technological class parts: design of the part in CADsoftware; generation of the parametrical link with MSExcel files; extract of the useful information for the technological design (mass, volume, surfaces; setting of the CNC lathe and necessary tools; programming of the CNC code for manufacturing. Given the large variety of the bushingsshapes and dimensions, the application focused on the jig bushings used in drilling processes.

  7. Evaluation of computer-aided detection and diagnosis systems.

    Science.gov (United States)

    Petrick, Nicholas; Sahiner, Berkman; Armato, Samuel G; Bert, Alberto; Correale, Loredana; Delsanto, Silvia; Freedman, Matthew T; Fryd, David; Gur, David; Hadjiiski, Lubomir; Huo, Zhimin; Jiang, Yulei; Morra, Lia; Paquerault, Sophie; Raykar, Vikas; Samuelson, Frank; Summers, Ronald M; Tourassi, Georgia; Yoshida, Hiroyuki; Zheng, Bin; Zhou, Chuan; Chan, Heang-Ping

    2013-08-01

    Computer-aided detection and diagnosis (CAD) systems are increasingly being used as an aid by clinicians for detection and interpretation of diseases. Computer-aided detection systems mark regions of an image that may reveal specific abnormalities and are used to alert clinicians to these regions during image interpretation. Computer-aided diagnosis systems provide an assessment of a disease using image-based information alone or in combination with other relevant diagnostic data and are used by clinicians as a decision support in developing their diagnoses. While CAD systems are commercially available, standardized approaches for evaluating and reporting their performance have not yet been fully formalized in the literature or in a standardization effort. This deficiency has led to difficulty in the comparison of CAD devices and in understanding how the reported performance might translate into clinical practice. To address these important issues, the American Association of Physicists in Medicine (AAPM) formed the Computer Aided Detection in Diagnostic Imaging Subcommittee (CADSC), in part, to develop recommendations on approaches for assessing CAD system performance. The purpose of this paper is to convey the opinions of the AAPM CADSC members and to stimulate the development of consensus approaches and "best practices" for evaluating CAD systems. Both the assessment of a standalone CAD system and the evaluation of the impact of CAD on end-users are discussed. It is hoped that awareness of these important evaluation elements and the CADSC recommendations will lead to further development of structured guidelines for CAD performance assessment. Proper assessment of CAD system performance is expected to increase the understanding of a CAD system's effectiveness and limitations, which is expected to stimulate further research and development efforts on CAD technologies, reduce problems due to improper use, and eventually improve the utility and efficacy of CAD in

  8. Peer Feedback in Computer Aided College English Writing Instruction

    OpenAIRE

    Ma Zhuo

    2016-01-01

    This study is to examine the acceptability of peer feedback in computer aided college English writing instruction. For the whole writing procedure, subjects in language labs were to take preparation, writing and evaluation stages, undergoing three editions suggested by peer feedbacks. For the first time reading, peers would comment on such general scale as subject and content of drafts, and the second focuses on specific items, for example the morphological, lexical and syntactical aspects, e...

  9. CADEE: Computer-Aided Directed Evolution of Enzymes

    Science.gov (United States)

    Amrein, Beat Anton; Steffen-Munsberg, Fabian; Szeler, Ireneusz; Purg, Miha; Kamerlin, Shina Caroline Lynn

    2017-01-01

    The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE) is presented which allows a drastic reduction in the time necessary to prepare and analyze in silico semi-automated directed evolution of enzymes. A pedagogical example of the application of CADEE to a real biological system is also presented in order to illustrate the CADEE workflow. PMID:28250941

  10. Some new algorithms for computer aided assembly planning

    OpenAIRE

    Kunica, Zoran; Vranješ, Božo; Hrman, Miljenko

    2015-01-01

    The paper depicts some of the improved and newly implemented algorithms of the computer aided design (CAD) based system for the plan generation of automatic assembly (GPAS), relating to definitions of assembly sequence and paths, space structuring (layout) of the assembly process for bench assembly product orientation, connectivity, and treatment of identical parts in a product. In the approach, the parts of which are presented in the paper, the mechanical product to be assembled is, initiall...

  11. Technology transfer of the Computer-Aided Prototyping System (CAPS)

    OpenAIRE

    Cooke, Robert P.

    1996-01-01

    The inability of the Department of Defense (DOD) to accurately and completely specify requirements for hard real-time software systems has resulted in poor productivity, schedule overruns, and software that is unmaintainable and unreliable. The Computer-Aided Prototyping System (CAPS) provides a capability to quickly develop functional prototypes to verify feasibility of system requirements early in the software development process. It was built to help program managers and software engineers...

  12. Computer Aided Grid Interface: An Interactive CFD Pre-Processor

    Science.gov (United States)

    Soni, Bharat K.

    1997-01-01

    NASA maintains an applications oriented computational fluid dynamics (CFD) efforts complementary to and in support of the aerodynamic-propulsion design and test activities. This is especially true at NASA/MSFC where the goal is to advance and optimize present and future liquid-fueled rocket engines. Numerical grid generation plays a significant role in the fluid flow simulations utilizing CFD. An overall goal of the current project was to develop a geometry-grid generation tool that will help engineers, scientists and CFD practitioners to analyze design problems involving complex geometries in a timely fashion. This goal is accomplished by developing the CAGI: Computer Aided Grid Interface system. The CAGI system is developed by integrating CAD/CAM (Computer Aided Design/Computer Aided Manufacturing) geometric system output and/or Initial Graphics Exchange Specification (IGES) files (including all the NASA-IGES entities), geometry manipulations and generations associated with grid constructions, and robust grid generation methodologies. This report describes the development process of the CAGI system.

  13. The computer-aided design of rubber-metal products

    Directory of Open Access Journals (Sweden)

    Pavlo S. Shvets

    2015-12-01

    Full Text Available The important problem in design of rubber-metal products is the optimization of their mass without sacrificing of proportionality factor is in the limits of standard. Aim: The aim of this work is to improve the computer-aided systems by development and implementation of improved optimization method in rubber-metal CAD systems for designers based on the reverse optimization. Materials and Methods: The paper studies the matters of computer-aided structural design of technical composite products composed of anisotropic materials that are essentially different in properties. Results: The structure of CAD systems for designers solving the problems of such design is offered and the work principles of its subsystems are described. It is shown that complicated systems optimization in CAD systems must consider as restrictions the entitative connection between separate elements of these systems within the area of the optimizing arguments. Conclusions: The problem of the “reverse” optimization when objective functions are the connectivity area parameters is considered. In many cases, this allows receiving solutions that are more effective during the computer-aided design process. The developed CAD system for designers was used during the production of rubber-metal shock absorbers at the Odessa Rubber Technical Articles Plant. The positive technical and economic effect was obtained.

  14. Cholesterol Granuloma of the Frontal Sinus: A Case Report

    Science.gov (United States)

    Marco, Manola; Ida, Casorelli; Francesco Luigi, Pietrafesa; Giampiero, Mottola; Domenico, Lacerenza; Giuseppe, Battiloro; Giuseppe, Patitucci; Giulia Anna Carmen, Vita

    2012-01-01

    Cholesterol granulomas are common in the mastoid antrum and air cells of the temporal bone. In the paranasal sinuses, especially in the frontal sinus, they have occasionally been mentioned in the literature. The pathogenesis is unknown, but the majority of the authors support the concept of airway obstruction in the cells well pneumatised of temporal bone and paranasal sinuses. The authors report a case of cholesterol granuloma of the frontal sinus treated with radical surgical techniques, and they also recommend an endoscopic approach to frontal sinus to restore or enlarge the nose-frontal canal and promote drainage and ventilation of the frontal sinus. PMID:23150840

  15. Cholesterol Granuloma of the Frontal Sinus: A Case Report

    Directory of Open Access Journals (Sweden)

    Manola Marco

    2012-01-01

    Full Text Available Cholesterol granulomas are common in the mastoid antrum and air cells of the temporal bone. In the paranasal sinuses, especially in the frontal sinus, they have occasionally been mentioned in the literature. The pathogenesis is unknown, but the majority of the authors support the concept of airway obstruction in the cells well pneumatised of temporal bone and paranasal sinuses. The authors report a case of cholesterol granuloma of the frontal sinus treated with radical surgical techniques, and they also recommend an endoscopic approach to frontal sinus to restore or enlarge the nose-frontal canal and promote drainage and ventilation of the frontal sinus.

  16. Applied anatomy of the posterior wall of sphenoid sinus during endoscopic extended transsphenoidal approach%内镜下扩大经蝶术中蝶窦后壁的应用解剖

    Institute of Scientific and Technical Information of China (English)

    刘环海; 廖建春; 范静平; 吴建; 赵舒薇; 党瑞山; 胡国汉; 王君玉; 彭浒

    2011-01-01

    Objective To provide anatomic data for accurately locating the important structures of sellar area and preventing injury during endoscopic extended transsphenoidal approach to the sellar area. Methods The extended transsphenoidal approach was employed in twenty cadavers via endoscope, and the posterior wall of sphenoid sinus was divided into different parts for localizing sella turcica, carotid protuberance and optic canal. Important structures were observed and measured under microscope. Results The posterior wall of sphenoid sinus was divided into five parts according to the four lines along the two sides of the two carotid protuberances. The depths of the sella turcica in the tuberculum sellae, anterior wall of sella turcica and sellar floor were (2. 20±0. 19 [0. 63-6.90]) mm, (0. 71±0.06 [0.36-2. 78]) mm, and (0. 94±0. 18 [0. 23-2.81]) mm, respectively. The transverse diameter, sagittal diameter and coronal diameter of pituitary gland were (14.72±1.07 [10. 92-18. 38]) mm, (10. 13±0. 92[9.37-12. 51]) mm and (5.13±0.74 (2.37-7.91]) mm, respectively. Conclusion The five parts of the posterior wall of sphenoid sinus in this study can facilitate the localization of important structures in the sellar area during the extended transsphenoidal approach to sellar area via endoscope, so as to prevent iatrogenic injury of vital structures in the sellar area.%目的 为鼻内镜下扩大经蝶蝶鞍区手术中准确定位及避免损伤鞍区重要解剖结构提供解剖学参数.方法 在鼻内镜下对20例头颅标本解剖,并对蝶窦后壁进行分区,准确定位蝶鞍、颈内动脉隆凸、视神经管.显微镜下观察、测量相关解剖结构.结果 沿颈内动脉隆凸两侧缘分别画2条直线,4条直线将蝶窦后壁分成5个区域.测量了蝶鞍不同部位的厚度:鞍结节[2.20±0.19(0.63~6.90)] mm,鞍前壁[0.71±0.06 (0.36~2.78)] mm;鞍底[0.94±0.18 (0.23~2.81)] mm.垂体的横径为[14.72±1.07(10.92~18.38)] mm

  17. Correction of facial and mandibular asymmetry using a computer aided design/computer aided manufacturing prefabricated titanium implant.

    Science.gov (United States)

    Watson, Jason; Hatamleh, Muhanad; Alwahadni, Ahed; Srinivasan, Dilip

    2014-05-01

    Patients with significant craniofacial asymmetry may have functional problems associated with their occlusion and aesthetic concerns related to the imbalance in soft and hard tissue profiles. This report details a case of facial asymmetry secondary to left mandible angle deficiency due to undergoing previous radiotherapy. We describe the correction of the bony deformity using computer aided design/computer aided manufacturing custom-made titanium onlay using novel direct metal laser sintering. The direct metal laser sintering onlay proved a very accurate operative fit and showed a good aesthetic correction of the bony defect with no reported complications postoperatively. It is a useful low-morbidity technique, and there is no resorption or associated donor-site complications.

  18. Methodology for Benefit Analysis of CAD/CAM (Computer-Aided Design/Computer-Aided Manufacturing) in USN Shipyards.

    Science.gov (United States)

    1984-03-01

    benefits of CAD/CAR and of the next generation technology, CIDER . The CADOS study (Ref. 13] offers a method to measure the intangibles of CAD/CAR...methodology that measures both tangible and intangible benefits of present CAD technology. This method would be hard to extend to CIDER technology because of...D-Ri38 398 METHODOLOGY FOR BENEFIT ANALYSIS OF CAD/CAM / (COMPUTER-HIDED DESIGN/COMPUTER-AIDED MANUFACTURING) IN USN SHIPYARDS(U) NAVAL POSTGRADUATE

  19. The effect of dexmedetomidine on the surgical field during functional endoscopic sinus surgery%右美托咪定对功能性鼻内镜手术视野的影响

    Institute of Scientific and Technical Information of China (English)

    杨阳; 陈彦青

    2015-01-01

    Objective To evaluate the surgical field during functional endoscopic sinus surgery after pre-operative intravenous infusion of dexmedetomidine.Method Forty patients in ASA classⅠorⅡundergoing functional endoscopic sinus surgery were randomly assigned into either the group D or the group C. Patients in group D received an intravenous infusion of dexmedetomidine before induction, while patients in group C were infused with the same amounts of normal saline. HR were observed before operation (T0), 10 minutes after infusion (T1), right after intubation (T2), and every 15 minutes from the beginning to the end of the surgery (T3~T11). The Fromme scores were recorded every 15 minutes from 15 minutes after surgery to 120 minutes after surgery, noted as Fromme scores from operation 15 minutes to operation 120 minutes (F1~F8).The modified Lund-Kennedy score (MLK), the operation time,the blood loss, and the levels of hemoglobin and hematocrit were recorded before surgery and one day after surgery. The scores of extubation quality were recorded right after extubation, and the Ramsay scores were taken 30 minutes after extubation. Adverse effects such as bradycardia, reflex hypertension, hypotension and ST-segment depression were recorded. Result Compared with the group C, the heart rate is relatively lower in group D with statistical significance (P 0.05). Compared with group C, the extubation quality and Ramsay score in group D were significantly higher with statistical difference (P0.05),与术前相比,两组Hb、Hct均明显降低(P0.05)。与C在相比, D组拔管质量、Ramsay评分较高,差异有统计学意义(P<0.05)。术中4例病人出现心动过缓,未发现反射性心动过速、反射性高血压、ST段下移等不良反应。结论术前静脉泵注右美托咪定可有效改善鼻内镜的术野能见度,并改善术后拔管质量及镇静程度。

  20. The Application Advantages of Flexible Laryngeal Mask Airway In EndoscopicSinus Surgery%可弯曲喉罩在鼻内镜手术应用的优势探讨

    Institute of Scientific and Technical Information of China (English)

    马佳佳; 李天佐

    2011-01-01

    目的:探讨与气管插管相比,可弯曲喉罩(Flexible Laryngeal Mask Airway) 在全麻鼻内镜手术(Endoscope Sinus Surgery,ESS) 中的应用优势.方法:择期行ESS 手术成年患者60 例,随机分为2组(F 组和T组),每组30 例.观察两组的血流动力学情况、术后恢复情况、手术出血量比较、用药情况、需用盐酸乌拉地尔和盐酸艾司洛尔控制性降压的例数等.结果:F 组血流动力学稳定性明显优于T组,P均0.05,F 组瑞芬太尼用量少于T组,P<0.05; 术中需降压例数F组少于T组,P<0.05.结论:可弯曲喉罩与气管插管相比在ESS 术中的应用更具优势.%Objective: Compared with endotracheal tube, discuss the Application advantages of Flexible Laryngeal Mask Airway in Endoscopic Sinus Surgery (ESS). Methods: Choose sixty ASA Ⅰ or Ⅱ selected ESS adult patients. Randomly divide them into two groups, F-team and T-team. Each group composes of 30 patients. Observation items conclude hemodynamic conditions, the postoperative recovery conditions, quantity of bleeding during the surgery, the exhausted dosage of propofol, remifentanil and sevoflurane and the controlled hypotension cases by urapidil hydrochloride and esmolo hydrochloride between the two teams. Results: The hemodynamics of the F-team is more stable than the T-team, P<0.01; the recovery time of the F-team is obviously less than the T-team.P<0.01, the recovery quality of the F-team is much better than the T-team, P<0.05; the quantity of bleeding during the surgery of the F-team is lower than the T-team, P<0.05; the dosage of remifentanil of the F-team is lower than the T-team,P<0.05; the controlled hypotension cases of the F-team is less than the T-team, P<0.05. Conclusion: The flexible laryngeal mask airway is more applicable to ESS.

  1. Project-Based Teaching-Learning Computer-Aided Engineering Tools

    Science.gov (United States)

    Simoes, J. A.; Relvas, C.; Moreira, R.

    2004-01-01

    Computer-aided design, computer-aided manufacturing, computer-aided analysis, reverse engineering and rapid prototyping are tools that play an important key role within product design. These are areas of technical knowledge that must be part of engineering and industrial design courses' curricula. This paper describes our teaching experience of…

  2. [Minimally invasive surgery for treating of complicated fronto-ethmoidal sinusitis].

    Science.gov (United States)

    Pomar Blanco, P; Martín Villares, C; San Román Carbajo, J; Fernández Pello, M; Tapia Risueño, M

    2005-01-01

    Functional endoscopic sinus surgery (FESS) is nowadays the "gold standard" for frontal sinus pathologies, but management of acute situations and the aproach and/or the extent of the surgery perfomed in the frontal recess remains controversial nowadays. We report our experience in 4 patients with orbital celulitis due to frontal sinusitis who underwent combined external surgery (mini-trephination) and endoscopic sinus surgery. All patients managed sinus patency without any complications. We found this combined sinusotomy as an easy, effective and reproductible technique in order to resolve the difficult surgical management of complicated frontal sinusitis.

  3. 鼻内镜手术中中鼻甲不同处理方法对嗅觉功能的影响%Effects on olfaction of different treatments to middle turbinate by endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    汪静波; 刘继丽; 廖志苏; 彭建华

    2008-01-01

    Objective To evaluate the effects of different treatments to middle turbinate by endo-scopic sinus surgery (ESS) on olfaction in patients with chronic sinusitis and nasal polyps. Methods ESS was performed on 74 cases of chronic sinusitis and nasal polyps. Proper treatments divided into the group of retaining middle turbinate, the group of forming middle turbinate and the group of partial endonasal middle turbinectomy which were applied to different pathological changes of middle turbinates. The olfactory function of the 74 patients was tested through the CCCRC olfactory testing method pre-operation and twenty-four weeks post-operation. The results were analyzed by analysis of variance. Results The olfaction after treat-ment of the three groups was significantly better than that of pre-operation (P 0.05). Conclusion Different treatments to middle turbinate by ESS is no obvious effects on olfaction.%目的 探讨慢性鼻窦炎鼻息肉患者鼻内镜手术中中鼻甲的不同处理方法对嗅觉功能的影响.方法 为74例慢性鼻窦炎鼻息肉患者进行鼻内镜手术,对不同病变的中鼻甲进行适当的处理.分为中鼻甲保留组(20例)、中鼻甲成形组(28例)和中鼻甲部分切除组(26例),采用美国康涅狄格化学感觉临床研究中心(CCCRC)嗅觉测试法在鼻内镜手术前和术后第24周进行嗅觉测试,将结果进行方差分析.结果 三组患者的嗅觉均较术前有所改善,中鼻甲保留组的CCCRC得分较术前提高0.84分,中鼻甲成形组较术前提高0.85分,中鼻甲部分切除组较术前提高0.87分.三组患者术后嗅觉与术前比较差异有统计学意义(P0.05).结论 鼻内镜手术中中鼻甲的不同处理方法对嗅觉无明显影响.

  4. [Computer-aided prescribing: from utopia to reality].

    Science.gov (United States)

    Suárez-Varela Ubeda, J; Beltrán Calvo, C; Molina López, T; Navarro Marín, P

    2005-05-31

    To determine whether the introduction of computer-aided prescribing helped reduce the administrative burden at primary care centers. Descriptive, cross-sectional design. Torreblanca Health Center in the province of Seville, southern Spain. From 29 October 2003 to the present a pilot project involving nine pharmacies in the basic health zone served by this health center has been running to evaluate computer-aided prescribing (the Receta XXI project) with real patients. All patients on the center's list of patients who came to the center for an administrative consultation to renew prescriptions for medications or supplies for long-term treatment. Total number of administrative visits per patient for patients who came to the center to renew prescriptions for long-term treatment, as recorded by the Diraya system (Historia Clinica Digital del Ciudadano, or Citizen's Digital Medical Record) during the period from February to July 2004. Total number of the same type of administrative visits recorded by the previous system (TASS) during the period from February to July 2003. The mean number of administrative visits per month during the period from February to July 2003 was 160, compared to a mean number of 64 visits during the period from February to July 2004. The reduction in the number of visits for prescription renewal was 60%. Introducing a system for computer-aided prescribing significantly reduced the number of administrative visits for prescription renewal for long-term treatment. This could help reduce the administrative burden considerably in primary care if the system were used in all centers.

  5. CATIA Core Tools Computer Aided Three-Dimensional Interactive Application

    CERN Document Server

    Michaud, Michel

    2012-01-01

    CATIA Core Tools: Computer-Aided Three-Dimensional Interactive Application explains how to use the essential features of this cutting-edge solution for product design and innovation. The book begins with the basics, such as launching the software, configuring the settings, and managing files. Next, you'll learn about sketching, modeling, drafting, and visualization tools and techniques. Easy-to-follow instructions along with detailed illustrations and screenshots help you get started using several CATIA workbenches right away. Reverse engineering--a valuable product development skill--is also covered in this practical resource.

  6. Efficient Use of Preisach Hysteresis Model in Computer Aided Design

    Directory of Open Access Journals (Sweden)

    IONITA, V.

    2013-05-01

    Full Text Available The paper presents a practical detailed analysis regarding the use of the classical Preisach hysteresis model, covering all the steps, from measuring the necessary data for the model identification to the implementation in a software code for Computer Aided Design (CAD in Electrical Engineering. An efficient numerical method is proposed and the hysteresis modeling accuracy is tested on magnetic recording materials. The procedure includes the correction of the experimental data, which are used for the hysteresis model identification, taking into account the demagnetizing effect for the sample that is measured in an open-circuit device (a vibrating sample magnetometer.

  7. A Computer Aided Consultant System for Mammogram Diagnosis

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    A computer-aided consultant system for mammogram diagnosis is proposed in this paper based on mam-mogram segmentation as an image mining technique, to aid radiologistis in X-ray film interpretation. The generalarchitecture of the system is introduced first, followed by a discussion of mammogram segmentation using logic fil-ter, an analysis of the statistical data to the diagnostics with respect to different clinical information, and a brief in-troduction to a fuzzy decision making subsystem. Finally some experimental results are given.

  8. Computer-Aided Design Of Sheet-Material Parts

    Science.gov (United States)

    Gilbert, Jeffrey L.; Paternoster, Vincent Y.; Levitt, Maureen L.; Osterloh, Mark R.

    1991-01-01

    Computer-aided-design system partly automates tedious process of designing and guiding assembly of small pieces of flat sheet material into large surfaces that approximate smoothly curved surfaces having complicated three-dimensional shapes. Capability provides for flexibility enabling designer to assess quickly and easily effects of changes in design in making engineering compromises among various sizes and shapes. Saves time and money in both design and fabrication. Used in rocket-engine application and other applications requiring design of sheet-material parts.

  9. Technology computer aided design simulation for VLSI MOSFET

    CERN Document Server

    Sarkar, Chandan Kumar

    2013-01-01

    Responding to recent developments and a growing VLSI circuit manufacturing market, Technology Computer Aided Design: Simulation for VLSI MOSFET examines advanced MOSFET processes and devices through TCAD numerical simulations. The book provides a balanced summary of TCAD and MOSFET basic concepts, equations, physics, and new technologies related to TCAD and MOSFET. A firm grasp of these concepts allows for the design of better models, thus streamlining the design process, saving time and money. This book places emphasis on the importance of modeling and simulations of VLSI MOS transistors and

  10. CADEE: Computer-Aided Directed Evolution of Enzymes

    Directory of Open Access Journals (Sweden)

    Beat Anton Amrein

    2017-01-01

    Full Text Available The tremendous interest in enzymes as biocatalysts has led to extensive work in enzyme engineering, as well as associated methodology development. Here, a new framework for computer-aided directed evolution of enzymes (CADEE is presented which allows a drastic reduction in the time necessary to prepare and analyze in silico semi-automated directed evolution of enzymes. A pedagogical example of the application of CADEE to a real biological system is also presented in order to illustrate the CADEE workflow.

  11. SNL Mechanical Computer Aided Design (MCAD) guide 2007.

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Brandon; Pollice, Stephanie L.; Martinez, Jack R.

    2007-12-01

    This document is considered a mechanical design best-practice guide to new and experienced designers alike. The contents consist of topics related to using Computer Aided Design (CAD) software, performing basic analyses, and using configuration management. The details specific to a particular topic have been leveraged against existing Product Realization Standard (PRS) and Technical Business Practice (TBP) requirements while maintaining alignment with sound engineering and design practices. This document is to be considered dynamic in that subsequent updates will be reflected in the main title, and each update will be published on an annual basis.

  12. 9th Asian Conference on Computer-Aided Surgery

    CERN Document Server

    2016-01-01

    This book presents the latest research advances in the theory, design, control, and application of robot systems intended for a variety of purposes such as manipulation, manufacturing, automation, surgery, locomotion, and biomechanics. Several chapters deal with fundamental kinematics in nature, including synthesis, calibration, redundancy, force control, dexterity, inverse and forward kinematics, kinematic singularities, and over-constrained systems. This book is a compilation of the extended versions of the very best papers selected from the many that were presented at the Asian Conference on Computer-Aided Surgery held September 16–18, 2013, in Tokyo, Japan (ACCAS 2013).

  13. Retrospective indexing (RI) - A computer-aided indexing technique

    Science.gov (United States)

    Buchan, Ronald L.

    1990-01-01

    An account is given of a method for data base-updating designated 'computer-aided indexing' (CAI) which has been very efficiently implemented at NASA's Scientific and Technical Information Facility by means of retrospective indexing. Novel terms added to the NASA Thesaurus will therefore proceed directly into both the NASA-RECON aerospace information system and its portion of the ESA-Information Retrieval Service, giving users full access to material thus indexed. If a given term appears in the title of a record, it is given special weight. An illustrative graphic representation of the CAI search strategy is presented.

  14. Selecting and effectively using a computer aided software engineering tool

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, D.L.

    1989-01-01

    Software engineering is a science by which user requirements are translated into a quality software product. Computer Aided Software Engineering (CASE) is the scientific application of a set of tools and methods to a software which results in high-quality, defect-free, and maintainable software products. The Computer Systems Engineering (CSE) group of Separations Technology at the Savannah River Site has successfully used CASE tools to produce high-quality, reliable, and maintainable software products. This paper details the selection process CSE used to acquire a commonly available CASE product and how the CSE group effectively used this CASE tool to consistently produce quality software. 9 refs.

  15. A comparative study of two computer-aided measurement methods

    OpenAIRE

    Gronau, Franziska

    2010-01-01

    Growth and developmental disorders of the elbow joint are frequent causes of lameness of the thoracic limb of the dog. Golden Retriever is one of the mainly affected breeds. Two different computer-aided methods of measurement will be compared in this study. The aim is to find out whether one of these measurement methods is more suitable to distinguish affected from unaffected joints and to recognize a possible predisposition for elbow dysplasia (ED). X-Rays of the elbow joints in the medio-la...

  16. The anatomy research of expanding vision of endoscopic maxillary sinus operation%扩大鼻内镜上颌窦手术视野的解剖学研究

    Institute of Scientific and Technical Information of China (English)

    刘杰; 刘婷婷; 张念凯

    2012-01-01

    Objective:To get the anatomical method of expangding vision of endoscopic maxillary sinus operation to providing guidance for the satisfactory surgical vision by measurement of nasal cavity and maxillary sinus relative structure. Method:By anatomical measurement from 30 human cranium preparations(21 Male,9 Female) , which were marinated by 10% formaldehyde solution,we tried to find out anatomical factors that influence expanding vision of endoscopic maxillary sinus operation. Result: Measurement of cranium preparations: respective distance between bone nasolacrimal canal anterior wall superior extremity, central extremity, bottom extremity and borderline of maxillary sinus anterior wall and medial wall were 0 mm,(l. 90±1.03)mm,(3. 29±1. 04)mm. Distance between anterior inferior part of bone nasolacrimal canal and anterior edge of inferior concha was(5. 13 ±0. 62)mm, and vertical distance between anterior inferior part of bone nasolacrimal canal and nasal bottom was (16. 89±0. 97)mm. The difference between right and left side had no signifisant statistic sense(P>0. 05). Removal of the bone area: the upper and lower diameter of part of the inferior turbinate attachment was (9. 43 ±1. 72)mm, anteroposterior diameter from top to bottom was (9. 76 ± 0. 83) mm, (11. 39 ± 0. 50) mm, (12. 85 ± 0. 66)mm, the upper and lower diameter of the following part of the inferior turbinate attachment was (13. 52 ± 0. 83)mm, anteroposterior diameter from top to bottom was (19.89 ± 1. 37)mm, (16. 59 ± 0. 77)mm, (12. 48± 0. 91) mm. Conclusion: Dissection from inferior turbinate anterior part approach to maxillary sinus could expand the endoscopic operation vision.%目的:通过对鼻腔和上颌窦相关解剖结构的观测,寻找扩大鼻内镜上颌窦手术视野的解剖学方法,为获得满意的手术视野提供指导.方法:以30例(60侧)经4%甲醛固定的成人尸头(男21例,女9例)为研究对象,去除鼻腔外侧壁的黏膜,保留各个重要骨性结

  17. Bacterial colonization or infection in chronic sinusitis.

    Science.gov (United States)

    Pandak, Nenad; Pajić-Penavić, Ivana; Sekelj, Alen; Tomić-Paradžik, Maja; Cabraja, Ivica; Miklaušić, Božana

    2011-12-01

    The aim of this study was the determination of bacteria present in maxillary and ethmoid cavities in patients with chronic sinusitis and to correlate these findings with bacteria simultaneously present in their nasopharynx. The purpose of this correlation was to establish the role of bacteria found in chronically inflamed sinuses and to evaluate if the bacteria present colonized or infected sinus mucosa. Nasopharyngeal and sinus swabs of 65 patients that underwent functional endoscopic sinus surgery were cultivated and at the same time the presence of leukocytes were determined in each swab. The most frequently found bacteria in nasopharynx were Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus spp., Streptococcus viridans and Streptococcus pneumoniae. Maxillary or ethmoidal sinus swabs yielded bacterial growth in 47 (72.31%) patients. The most frequently found bacteria in sinuses were Staphylococcus epidermidis, Staphylococcus aureus, Klebsiella spp. and Streptococci (pneumoniae, viridans and spp.). The insignificant number of leukocytes was present in each sinus and nasopharyngeal swab. Every published microbiology study of chronic sinusitis proved that sinus mucosa were colonized with bacteria and not infected, yet antibiotic therapy was discussed making no difference between infection and colonization. Chronic sinusitis should be considered a chronic inflammatory condition rather than bacterial infection, so routine antibiotic therapy should be avoided. Empiric antibiotic therapy should be prescribed only in cases when the acute exacerbation of chronic sinusitis occurs and the antibiotics prescribed should aim the usual bacteria causing acute sinusitis. In case of therapy failure, antibiotics should be changed having in mind that under certain circumstances any bacteria colonizing sinus mucosa can cause acute exacerbation of chronic sinusitis.

  18. 对比传统鼻镜手术与影像导航下鼻镜手术对鼻窦骨瘤患者疗效及预后影响的差异%Comparison of the effects and prognostic differences of traditional nasal endoscopic operation and image navigation under nasal endoscopic operation on patients with sinus osteoma

    Institute of Scientific and Technical Information of China (English)

    查潇逸

    2016-01-01

    目的 探讨传统鼻镜手术与影像导航下鼻镜手术对鼻窦骨瘤患者疗效及预后影响的差异.方法 选取59例鼻窦骨瘤患者为研究对象,根据其入院就诊次序分成影像导航组(A组,n =30)和传统手术组(B组,n =29).A组予以传统鼻镜手术方案,B组在影像导航下行鼻镜手术.比对两组患者术程、术中出血量、总住院时间等治疗指标的差异,行为期2年的随访,记录其复发及并发症发生情况.结果 ①两组患者术中出血量及术后住院时间等指标比较差异未见统计学意义(P>0.05);A组手术时间为(81.5±7.0) min,长于B组[(61.9±6.2) min],差异有统计学意义(P<0.05);②在为期2年的随访中,A组无复发病例,B组额窦复发2例,筛窦复发4例,复发率为20.7%,两组比较差异有统计学意义(P<0.05);A组术后相关并发症发生率为10.0%,与B组的41.4%比较差异有统计学意义(P<0.05).结论 对鼻窦骨瘤患者予以影像导航下鼻镜手术疗效确切,值得临床推广.%Objective To investigate the effect and prognostic differences of traditional nasal endoscopic operation and image navigation under nasal endoscopic operation on patients with sinus osteoma.Methods Fifty-nine cases with nasal sinus osteoma patients as the research object, according to the hospital admission sequence were divided into image navigation group(group A, n =30) and conventional operation group(group B, n =29).Group A was treated by traditional nasal endoscopic operation scheme, group B was treated by nasal endoscopic operation image navigation.The differences of bleeding volume at preoperative, intraoperative, the length of hospital stay and other indexed of patients in two groups were compared, followed-up for 2 years, recorded its recurrence and complications.Results ① The difference of amount of bleeding at intraoperative and hospital time after surgery and other indicators of two groups had no significant difference (P >0

  19. Computer-aided ultrasonic inspection of steam turbine rotors

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, K.H.; Weber, M.; Weiss, M. [GEC ALSTHOM Energie GmbH, Nuremberg (Germany)

    1998-12-31

    As the output and economic value of power plants increase, the detection and sizing of the type of flaws liable to occur in the rotors of turbines using ultrasonic methods assumes increasing importance. An ultrasonic inspection carried out at considerable expense is expected to bring to light all safety-relevant flaws and to enable their size to be determined so as to permit a fracture-mechanics analysis to assess the reliability of the rotor under all possible stresses arising in operation with a high degree of accuracy. The advanced computer-aided ultrasonic inspection of steam turbine rotors have improved reliability, accuracy and reproducibility of ultrasonic inspection. Further, there has been an improvement in the resolution of resolvable group indications by applying reconstruction and imagine methods. In general, it is also true for the advanced computer-aided ultrasonic inspection methods that, in the case of flaw-affected forgings, automated data acquisition provides a substantial rationalization and a significant documentation of the results for the fracture mechanics assessment compared to manual inspection. (orig.) 8 refs.

  20. NALDA (Naval Aviation Logistics Data Analysis) CAI (computer aided instruction)

    Energy Technology Data Exchange (ETDEWEB)

    Handler, B.H. (Oak Ridge K-25 Site, TN (USA)); France, P.A.; Frey, S.C.; Gaubas, N.F.; Hyland, K.J.; Lindsey, A.M.; Manley, D.O. (Oak Ridge Associated Universities, Inc., TN (USA)); Hunnum, W.H. (North Carolina Univ., Chapel Hill, NC (USA)); Smith, D.L. (Memphis State Univ., TN (USA))

    1990-07-01

    Data Systems Engineering Organization (DSEO) personnel developed a prototype computer aided instruction CAI system for the Naval Aviation Logistics Data Analysis (NALDA) system. The objective of this project was to provide a CAI prototype that could be used as an enhancement to existing NALDA training. The CAI prototype project was performed in phases. The task undertaken in Phase I was to analyze the problem and the alternative solutions and to develop a set of recommendations on how best to proceed. The findings from Phase I are documented in Recommended CAI Approach for the NALDA System (Duncan et al., 1987). In Phase II, a structured design and specifications were developed, and a prototype CAI system was created. A report, NALDA CAI Prototype: Phase II Final Report, was written to record the findings and results of Phase II. NALDA CAI: Recommendations for an Advanced Instructional Model, is comprised of related papers encompassing research on computer aided instruction CAI, newly developing training technologies, instructional systems development, and an Advanced Instructional Model. These topics were selected because of their relevancy to the CAI needs of NALDA. These papers provide general background information on various aspects of CAI and give a broad overview of new technologies and their impact on the future design and development of training programs. The paper within have been index separately elsewhere.

  1. Assessment technique for computer-aided manufactured sockets

    Directory of Open Access Journals (Sweden)

    Joan E. Sanders, PhD

    2011-08-01

    Full Text Available This article presents an assessment technique for testing the quality of prosthetic socket fabrication processes at computer-aided manufacturing facilities. The assessment technique is potentially useful to both facilities making sockets and companies marketing manufacturing equipment seeking to assess and improve product quality. To execute the assessment technique, an evaluator fabricates a collection of test models and sockets using the manufacturing suite under evaluation, then measures their shapes using scanning equipment. Overall socket quality is assessed by comparing socket shapes with electronic file (e-file shapes. To characterize carving performance, model shapes are compared with e-file shapes. To characterize forming performance, socket shapes are compared with model shapes. The mean radial error (MRE, which is the average difference in radii between the two compared shapes, provides insight into sizing quality. Interquartile range (IQR, the range of radial error for the best-matched half of the points on the compared socket surfaces, provides insight into regional shape quality. The source(s of socket shape error may be pinpointed by separately determining MRE and IQR for carving and forming. The developed assessment technique may provide a useful tool to the prosthetics community and industry to help identify problems and limitations in computer-aided manufacturing and give insight into appropriate modifications to overcome them.

  2. Computer-aided light sheet flow visualization using photogrammetry

    Science.gov (United States)

    Stacy, Kathryn; Severance, Kurt; Childers, Brooks A.

    1994-01-01

    A computer-aided flow visualization process has been developed to analyze video images acquired from rotating and translating light sheet visualization systems. The computer process integrates a mathematical model for image reconstruction, advanced computer graphics concepts, and digital image processing to provide a quantitative and a visual analysis capability. The image reconstruction model, based on photogrammetry, uses knowledge of the camera and light sheet locations and orientations to project two-dimensional light sheet video images into three-dimensional space. A sophisticated computer visualization package, commonly used to analyze computational fluid dynamics (CFD) results, was chosen to interactively display the reconstructed light sheet images with the numerical surface geometry for the model or aircraft under study. The photogrammetric reconstruction technique and the image processing and computer graphics techniques and equipment are described. Results of the computer-aided process applied to both a wind tunnel translating light sheet experiment and an in-flight rotating light sheet experiment are presented. The capability to compare reconstructed experimental light sheet images with CFD solutions in the same graphics environment is also demonstrated.

  3. Computer-aided morphometry of liver inflammation in needle biopsies

    Institute of Scientific and Technical Information of China (English)

    N Dioguardi; B Franceschini; C Russo; F Grizzi

    2005-01-01

    AIM: To introduce a computer-aided morphometric method for quantifying the necro-inflammatory phase in liver biopsy specimens using fractal geometry and Delaunay's triangulation.METHODS: Two-micrometer thick biopsy sections taken from 78 chronic hepatitis C virus-infected patients were immunohistochemically treated to identify the inflammatory cells. An automatic computer-aided image analysis system was used to define the inflammatory cell network defined on the basis of Delaunay's triangulation,and the inflammatory cells were geometrically classified as forming a cluster (an aggregation of a minimum of three cells) or as being irregularly distributed within the tissue. The phase of inflammatory activity was estimated using Hurst's exponent.RESULTS: The proposed automatic method was rapid and objective. It could not only provide rigorous results expressed by scalar numbers, but also allow the state of the whole organ to be represented by Hurst's exponent with an error of no more than 12%.CONCLUSION: The availability of rigorous metrical measures and the reasonable representativeness of the status of the organ as a whole raise the question as to whether the indication for hepatic biopsy should be revised by establishing clear rules concerning the contraindications suggested by its invasiveness and subjective interpretation.

  4. Computer-aided dermoscopy for diagnosis of melanoma

    Directory of Open Access Journals (Sweden)

    Naraghi Zahra S

    2005-07-01

    Full Text Available Abstract Background Computer-aided dermoscopy using artificial neural networks has been reported to be an accurate tool for the evaluation of pigmented skin lesions. We set out to determine the sensitivity and specificity of a computer-aided dermoscopy system for diagnosis of melanoma in Iranian patients. Methods We studied 122 pigmented skin lesions which were referred for diagnostic evaluation or cosmetic reasons. Each lesion was examined by two clinicians with naked eyes and all of their clinical diagnostic considerations were recorded. The lesions were analyzed using a microDERM® dermoscopy unit. The output value of the software for each lesion was a score between 0 and 10. All of the lesions were excised and examined histologically. Results Histopathological examination revealed melanoma in six lesions. Considering only the most likely clinical diagnosis, sensitivity and specificity of clinical examination for diagnosis of melanoma were 83% and 96%, respectively. Considering all clinical diagnostic considerations, the sensitivity and specificity were 100% and 89%. Choosing a cut-off point of 7.88 for dermoscopy score, the sensitivity and specificity of the score for diagnosis of melanoma were 83% and 96%, respectively. Setting the cut-off point at 7.34, the sensitivity and specificity were 100% and 90%. Conclusion The diagnostic accuracy of the dermoscopy system was at the level of clinical examination by dermatologists with naked eyes. This system may represent a useful tool for screening of melanoma, particularly at centers not experienced in the field of pigmented skin lesions.

  5. Computer-aided detection of early cancer in the esophagus using HD endoscopy images

    Science.gov (United States)

    van der Sommen, Fons; Zinger, Svitlana; Schoon, Erik J.; de With, Peter H. N.

    2013-02-01

    Esophageal cancer is the fastest rising type of cancer in the Western world. The recent development of High-Definition (HD) endoscopy has enabled the specialist physician to identify cancer at an early stage. Nevertheless, it still requires considerable effort and training to be able to recognize these irregularities associated with early cancer. As a first step towards a Computer-Aided Detection (CAD) system that supports the physician in finding these early stages of cancer, we propose an algorithm that is able to identify irregularities in the esophagus automatically, based on HD endoscopic images. The concept employs tile-based processing, so our system is not only able to identify that an endoscopic image contains early cancer, but it can also locate it. The identification is based on the following steps: (1) preprocessing, (2) feature extraction with dimensionality reduction, (3) classification. We evaluate the detection performance in RGB, HSI and YCbCr color space using the Color Histogram (CH) and Gabor features and we compare with other well-known features to describe texture. For classification, we employ a Support Vector Machine (SVM) and evaluate its performance using different parameters and kernel functions. In experiments, our system achieves a classification accuracy of 95.9% on 50×50 pixel tiles of tumorous and normal tissue and reaches an Area Under the Curve (AUC) of 0.990. In 22 clinical examples our algorithm was able to identify all (pre-)cancerous regions and annotate those regions reasonably well. The experimental and clinical validation are considered promising for a CAD system that supports the physician in finding early stage cancer.

  6. Relationship between development of accessory maxillary sinus and chronic sinusitis

    Directory of Open Access Journals (Sweden)

    Caner Sahin

    2015-01-01

    Full Text Available Background: We aimed to investigate whether there is a relationship between development of accessory maxillary osmium (AMO and chronic sinusitis. Material and Methods: A total of 100 patients who had endoscopic sinus surgery for chronic rhinosinusitis (CRS constituted the study group while 100 patients who had septoplasty were taken as the control group. The patients were examined for the presence of AMO using rigid endoscope. Results: The prevalence of AMO was 14% in the rhinosinusitis group and 9% in the control group. The difference between the groups was statistically significant (P < 0.05. Conclusion: Our study revealed that AMO prevalence is significantly higher in patients with CRS when compared with the controls. CRS may enhance perforation of fontanelle and formation of AMO.

  7. The therapeutic effect of endoscopic-assisted radiofrequency plasma ablation on odontogenic maxillary sinusitis%内镜辅助等离子射频消融手术治疗牙源性上颌窦炎近期疗效观察

    Institute of Scientific and Technical Information of China (English)

    颜光启; 郭永峰; 孙宁宁; 周青; 卢利

    2012-01-01

    PURPOSE: To explore the therapeutic effect of endoscopic -assisted on odontogenic maxillary sinusitis. METHODS: The clinical data of thirty-five patients with odontogenic maxillary sinusitis were retrospectively analyzed, including 23 cases who underwent endoscopic-assisted and 12 cases underwent Caldwell-Luc operation, treatment was applied under the help of antrotomy via middle nasal meatus with endoscope. The surgeon performed operations from anterior wall of maxillary sinus as approaches and used endoscope to locate the inflammatory area, and the treatment of radiofrequency plasma ablation was used to ablate the inflamed mucosa of maxillary sinus. In addition, 12 patients underwent Caldwell-Luc operation. The effects of two kinds of operation were compared with each other. RESULTS: Patients with Caldwell-Luc operation were hospitalized for 11 days. The complication of Caldwell-Luc operation included facial swelling, facial numbness and toothache in 12 patients, 7 patients and 6 patients, respectively. The mean hospital day of patients with endoscopic assisted- was 5 days. No complications occurred and the apertures of middle nasal meatus recovered to be unobstructed 3 months after operation. No recurrence was found during 3 months follow -up. CONCLUSION: Compared with Caldwell -Luc operation, endoscopic -assisted on odontogenic maxillary sinusitis reserved the normal maxillary sinus mucosa and reduced the length of patient stay as well as removed the inflammatory tissues. Therefore, endoscopic-assisted was beneficial to recovery of patients with operation.%目的:探讨采用内镜辅助下等离子射频消融手术治疗牙源性上颌窦炎的效果.方法:回顾性分析35例牙源性上颌窦炎患者的资料.其中采用内镜辅助下等离子低温射频治疗患者23例,手术从患侧上颌窦前壁开窗,鼻内镜经中鼻道开口或在开窗处进路,在内镜下探查炎症病灶的具体部位,在去除病灶牙的同时,应用等离子低温

  8. 慢性鼻窦炎鼻内镜术后耳穴贴压辅助治疗的疗效观察%Clinical efficacy of adjuvant auricular point sticking on chronic rhinosinusitis patients after endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    郭成兵; 吴曙辉; 朱红; 杨艳; 闫勇; 朱静静

    2016-01-01

    Objective:To investigate the clinical efficacy of conventional western medicine combined with auricular point stickingon chronic rhinosinusitispatientsafter nasal endoscopic surgery . Methods: 124 cases of CRS patients were randomly divided into control group and treatment group .The control group was given routine treatment ,the treatment group was given auricular point sticking based on conventional medicine .The clinical efficacy and the improvement of the symptoms of both groups were observed .Results:The effective rate of the control group and the treatment group were 73 .77% and 90 .47%(P<0 .05) 6 months after the operation .At 1 month ,3 months and 6 months after surgery ,the VAS (visual analogue scale) scores of both groups were improved ,and the score of the treatment group became better with the treatment time(P<0 .05) . Conclusions :Conventional western medicine combined with auricular point stickinghas better efficacyin CRS patients after ESS , w hich can effectively improve the patients'subjective symptoms .%目的:探讨常规西医治疗结合耳穴贴压疗法在慢性鼻窦炎(chronic rhinosinusitis ,CRS )鼻内窥镜术(endoscopic sinus surgery ,ESS)后的临床疗效。方法:将124例CRS患者随机分为对照组和治疗组,对照组给予常规治疗,治疗组在此基础上给予耳穴贴压治疗。观察两组治疗的临床疗效和症状改善情况。结果:患者术后6个月,对照组与治疗组治疗的有效率分别为73.77%、90.47%(P<0.05)。术后1个月、3个月和6个月,两组视觉模拟评分(visual analogue scale ,VAS)评分均有改善,随着治疗时间的推移进一步改善,以治疗组更明显(P<0.05)。结论:CRS患者ESS术后在常规西医治疗基础上辅以耳穴贴压治疗的疗效更优,能有效改善患者症状。

  9. Computer-aided diagnosis in chest radiography: Beyond nodules

    Energy Technology Data Exchange (ETDEWEB)

    Ginneken, Bram van [University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht (Netherlands)], E-mail: bram@isi.uu.nl; Hogeweg, Laurens; Prokop, Mathias [University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht (Netherlands)

    2009-11-15

    Chest radiographs are the most common exam in radiology. They are essential for the management of various diseases associated with high mortality and morbidity and display a wide range of findings, many of them subtle. In this survey we identify a number of areas beyond pulmonary nodules that could benefit from computer-aided detection and diagnosis (CAD) in chest radiography. These include interstitial infiltrates, catheter tip detection, size measurements, detection of pneumothorax and detection and quantification of emphysema. Recent work in these areas is surveyed, but we conclude that the amount of research devoted to these topics is modest. Reasons for the slow pace of CAD development in chest radiography beyond nodules are discussed.

  10. Computer-Aided Numerical Inversion of Laplace Transform

    Directory of Open Access Journals (Sweden)

    Umesh Kumar

    2000-01-01

    Full Text Available This paper explores the technique for the computer aided numerical inversion of Laplace transform. The inversion technique is based on the properties of a family of three parameter exponential probability density functions. The only limitation in the technique is the word length of the computer being used. The Laplace transform has been used extensively in the frequency domain solution of linear, lumped time invariant networks but its application to the time domain has been limited, mainly because of the difficulty in finding the necessary poles and residues. The numerical inversion technique mentioned above does away with the poles and residues but uses precomputed numbers to find the time response. This technique is applicable to the solution of partially differentiable equations and certain classes of linear systems with time varying components.

  11. Computer-aided conceptual design of Air Cushion Vehicles

    Science.gov (United States)

    Band, E. G. U.; Lavis, D. R.

    This paper describes the development and use of a computer-aided design tool which has been used to explore preferred options for amphibious Air-Cushion Vehicle (ACV) and Surface-Effect Ship (SES) designs in support of U.S. Navy and U.S. Army programs. The tool, referred to as the ACV Design Synthesis Model (ADSM), is an interactive computer program which provides a description of feasible ACV or SES concepts that could be developed, by a competent design team, to perform the mission described by the input parameters. The paper discusses how the program was used to explore parametrically the design of a range of self-propelled hoverbarges to meet requirements of the U.S. Army Logistics Over the Shore (LOTS) phases of an amphibious landing. Examples of results are presented to illustrate the method used in determining design and performance trade-offs.

  12. Computer Aided Interpretation Approach for Optical Tomographic Images

    CERN Document Server

    Klose, Christian D; Netz, Uwe; Beuthan, Juergen; Hielscher, Andreas H

    2010-01-01

    A computer-aided interpretation approach is proposed to detect rheumatic arthritis (RA) of human finger joints in optical tomographic images. The image interpretation method employs a multi-variate signal detection analysis aided by a machine learning classification algorithm, called Self-Organizing Mapping (SOM). Unlike in previous studies, this allows for combining multiple physical image parameters, such as minimum and maximum values of the absorption coefficient for identifying affected and not affected joints. Classification performances obtained by the proposed method were evaluated in terms of sensitivity, specificity, Youden index, and mutual information. Different methods (i.e., clinical diagnostics, ultrasound imaging, magnet resonance imaging and inspection of optical tomographic images), were used as "ground truth"-benchmarks to determine the performance of image interpretations. Using data from 100 finger joints, findings suggest that some parameter combinations lead to higher sensitivities while...

  13. 13th International Conference on Computer Aided Engineering

    CERN Document Server

    Pietrusiak, Damian

    2017-01-01

    These proceedings of the 13th International Conference on Computer Aided Engineering present selected papers from the event, which was held in Polanica Zdrój, Poland, from June 22 to 25, 2016. The contributions are organized according to thematic sections on the design and manufacture of machines and technical systems; durability prediction; repairs and retrofitting of power equipment; strength and thermodynamic analyses for power equipment; design and calculation of various types of load-carrying structures; numerical methods for dimensioning materials handling; and long-distance transport equipment. The conference and its proceedings offer a major interdisciplinary forum for researchers and engineers to present the most innovative studies and advances in this dynamic field.

  14. Computer aided microbial safety design of food processes.

    Science.gov (United States)

    Schellekens, M; Martens, T; Roberts, T A; Mackey, B M; Nicolaï, B M; Van Impe, J F; De Baerdemaeker, J

    1994-12-01

    To reduce the time required for product development, to avoid expensive experimental tests, and to quantify safety risks for fresh products and the consequence of processing there is a growing interest in computer aided food process design. This paper discusses the application of hybrid object-oriented and rule-based expert system technology to represent the data and knowledge of microbial experts and food engineers. Finite element models for heat transfer calculation routines, microbial growth and inactivation models and texture kinetics are combined with food composition data, thermophysical properties, process steps and expert knowledge on type and quantity of microbial contamination. A prototype system has been developed to evaluate changes in food composition, process steps and process parameters on microbiological safety and textual quality of foods.

  15. Computer-Aided Multiscale Modelling for Chemical Process Engineering

    DEFF Research Database (Denmark)

    Morales Rodriguez, Ricardo; Gani, Rafiqul

    2007-01-01

    T) for model translation, analysis and solution. The integration of ModDev, MoT and ICAS or any other external software or process simulator (using COM-Objects) permits the generation of different models and/or process configurations for purposes of simulation, design and analysis. Consequently, it is possible......Chemical processes are generally modeled through monoscale approaches, which, while not adequate, satisfy a useful role in product-process design. In this case, use of a multi-dimensional and multi-scale model-based approach has importance in product-process development. A computer-aided framework...... for model generation, analysis, solution and implementation is necessary for the development and application of the desired model-based approach for product-centric process design/analysis. This goal is achieved through the combination of a system for model development (ModDev), and a modelling tool (Mo...

  16. Systematic Computer-Aided Framework for Sustainable Chemical Product Design

    DEFF Research Database (Denmark)

    Cignitti, Stefano; Zhang, Lei; Kalakul, Sawitree

    Computer-aided product design (CAPD) is a method for the generation and selection of novel pure, mixed and blended chemical products [1]. In CAPD, the chemical product is generated and selected based on defined structure, property and process/application constraints. Several challenges exist...... for CAPD, including the accuracy of the property estimation, molecular structure generation, inclusion of sustainability, process and application targets and needs in the problem formulation. CAPD has been widely utilized for the synthesis of several types of products, such as solvents, polymers, fuels...... and formulated products [2]. However, for product design problems where the process needs and sustainability possess demanding constraints, the complexity of the problem is increased as the relation between product property, sustainability and process criteria is difficult to mathematically define. In this work...

  17. On computer-aided design of aerospace vehicles

    Science.gov (United States)

    Sobieszczanski, J. E.; Voigt, S. J.; Fulton, R. E.

    1974-01-01

    Digital computers are being used in many engineering activities to support design work. This paper provides an overview of some of this work as it relates to the design of aerospace vehicles. Discussions are given of some of the complexities of the design process which lead to large design costs and time. A number of important but disjointed computer capabilities have evolved over the years in analysis, optimization, and graphics, and such capabilities aid in addressing the problem of design complexity. Examples of existing computer-aided design (CAD) systems are given and trends for future CAD systems are indicated, as well as their relationship to pertinent data management technology. It is suggested that major gains in design capability will occur through continued development of CAD methodology and that these gains may be accelerated through a large focused effort.

  18. Computer- Aided Design in Power Engineering Application of Software Tools

    CERN Document Server

    Stojkovic, Zlatan

    2012-01-01

    This textbooks demonstrates the application of software tools in solving a series of problems from the field of designing power system structures and systems. It contains four chapters: The first chapter leads the reader through all the phases necessary in the procedures of computer aided modeling and simulation. It guides through the complex problems presenting on the basis of eleven original examples. The second chapter presents  application of software tools in power system calculations of power systems equipment design. Several design example calculations are carried out using engineering standards like MATLAB, EMTP/ATP, Excel & Access, AutoCAD and Simulink. The third chapters focuses on the graphical documentation using a collection of software tools (AutoCAD, EPLAN, SIMARIS SIVACON, SIMARIS DESIGN) which enable the complete automation of the development of graphical documentation of a power systems. In the fourth chapter, the application of software tools in the project management in power systems ...

  19. Computer aided planning and navigation for orbito-zygomatic reconstruction

    CERN Document Server

    Marecaux, Christophe; Payan, Yohan; Boutault, Franck

    2007-01-01

    This paper suggests a full protocol of Computer Aided Surgery as previously recommended in literature addressing the challenging task of primary or secondary reconstruction of orbito-zygomatic dislocation. First, on a specifically developed planning software, the best zygoma reduction and orbital boundaries reconstruction to achieve skeletal symmetry are determined. This treatment plan is then transferred to the 3D Navigation Systems within the operating room. After patient's anatomy registration to his preoperative CT scan data, the navigation system allows zygomatic guiding to its planned reduced location and bone orbital volume restoration control. The feasibility of this technique was checked in 3 patients with major orbito-zygomatic deformities. Preliminary clinical results are presented.

  20. Computer aided systems human engineering: A hypermedia tool

    Science.gov (United States)

    Boff, Kenneth R.; Monk, Donald L.; Cody, William J.

    1992-01-01

    The Computer Aided Systems Human Engineering (CASHE) system, Version 1.0, is a multimedia ergonomics database on CD-ROM for the Apple Macintosh II computer, being developed for use by human system designers, educators, and researchers. It will initially be available on CD-ROM and will allow users to access ergonomics data and models stored electronically as text, graphics, and audio. The CASHE CD-ROM, Version 1.0 will contain the Boff and Lincoln (1988) Engineering Data Compendium, MIL-STD-1472D and a unique, interactive simulation capability, the Perception and Performance Prototyper. Its features also include a specialized data retrieval, scaling, and analysis capability and the state of the art in information retrieval, browsing, and navigation.

  1. Evolution of Geometric Sensitivity Derivatives from Computer Aided Design Models

    Science.gov (United States)

    Jones, William T.; Lazzara, David; Haimes, Robert

    2010-01-01

    The generation of design parameter sensitivity derivatives is required for gradient-based optimization. Such sensitivity derivatives are elusive at best when working with geometry defined within the solid modeling context of Computer-Aided Design (CAD) systems. Solid modeling CAD systems are often proprietary and always complex, thereby necessitating ad hoc procedures to infer parameter sensitivity. A new perspective is presented that makes direct use of the hierarchical associativity of CAD features to trace their evolution and thereby track design parameter sensitivity. In contrast to ad hoc methods, this method provides a more concise procedure following the model design intent and determining the sensitivity of CAD geometry directly to its respective defining parameters.

  2. Computer-aided modeling framework – a generic modeling template

    DEFF Research Database (Denmark)

    Fedorova, Marina; Sin, Gürkan; Gani, Rafiqul

    This work focuses on the development of a computer-aided modeling framework. The framework is a knowledge-based system that is built on a generic modeling language and structured on workflows for different modeling tasks. The overall objective is to support model developers and users to generate...... and test models systematically, efficiently and reliably. In this way, development of products and processes can be made faster, cheaper and more efficient. In this contribution, as part of the framework, a generic modeling template for the systematic derivation of problem specific models is presented....... The application of the modeling template is highlighted with a case study related to the modeling of a catalytic membrane reactor coupling dehydrogenation of ethylbenzene with hydrogenation of nitrobenzene...

  3. Computer-aided assessment in statistics: the CAMPUS project

    Directory of Open Access Journals (Sweden)

    Neville Hunt

    1998-12-01

    Full Text Available The relentless drive for 'efficiency' in higher education, and the consequent increase in workloads, has given university teachers a compelling incentive to investigate alternative forms of assessment. Some forms of assessment with a clear educational value can no longer be entertained because of the burden placed on the teacher. An added concern is plagiarism, which anecdotal evidence would suggest is on the increase yet which is difficult to detect in large modules with more than one assessor. While computer-aided assessment (CAA has an enthusiastic following, it is not clear to many teachers that it either reduces workloads or reduces the risk of cheating. In an ideal world, most teachers would prefer to give individual attention and personal feedback to each student when marking their work. In this sense CAA must be seen as second best and will therefore be used only if it is seen to offer significant benefits in terms of reduced workloads or increased validity.

  4. Computer Aided Safety Assessment(CASA) Tool for ISS Payloads

    Science.gov (United States)

    Hochstein, Jason; Festa, Fabrizio

    2010-09-01

    In an effort to streamline the processes established by the partners of the International Space Station(ISS) to certify the safety of hardware and experiments destined for the Station, the European Space Agency’s(ESA) ISS System Safety Team is developing the Computer Aided Safety Assessment(CASA) tool suite. These software tools guide payload developers through the creation process of two types of standard payload hazard reports via a series of questions following a predetermined logic. The responses provided by the user are used by the CASA system to complete the majority of each hazard report requisite for payload flight safety reviews, employing consistent, approved descriptions of most hazards, hazard causes, controls and verification methods. Though some manual inputs will still be required to complete these reports, working with CASA will considerably reduce the amount of time necessary to review the documentation by agency safety authorities.

  5. Shape Signatures: speeding up computer aided drug discovery.

    Science.gov (United States)

    Meek, Peter J; Liu, ZhiWei; Tian, LiFeng; Wang, Ching Y; Welsh, William J; Zauhar, Randy J

    2006-10-01

    Identifying potential lead molecules is becoming a more automated process. We review Shape Signatures, a tool that is effective and easy to use compared with most computer aided drug design techniques. Laboratory researchers can apply this in silico technique cost-effectively without the need for specialized computer backgrounds. Identifying a potential lead molecule requires database screening, and this becomes rate-limiting once the database becomes too large. The use of Shape Signatures eliminates this concern and offers molecule screening rates that are in advance of any currently available method. Shape Signatures provides a conduit for researchers to conduct rapid identification of potential active molecules, and studies with this tool can be initiated with only one bioactive lead or receptor site.

  6. Systematic Methods and Tools for Computer Aided Modelling

    DEFF Research Database (Denmark)

    Fedorova, Marina

    -friendly system, which will make the model development process easier and faster and provide the way for unified and consistent model documentation. The modeller can use the template for their specific problem or to extend and/or adopt a model. This is based on the idea of model reuse, which emphasizes the use...... and processes can be faster, cheaper and very efficient. The developed modelling framework involves five main elements: 1) a modelling tool, that includes algorithms for model generation; 2) a template library, which provides building blocks for the templates (generic models previously developed); 3) computer...... aided methods and tools, that include procedures to perform model translation, model analysis, model verification/validation, model solution and model documentation; 4) model transfer – export/import to/from other application for further extension and application – several types of formats, such as XML...

  7. PACS-Based Computer-Aided Detection and Diagnosis

    Science.gov (United States)

    Huang, H. K. (Bernie); Liu, Brent J.; Le, Anh HongTu; Documet, Jorge

    The ultimate goal of Picture Archiving and Communication System (PACS)-based Computer-Aided Detection and Diagnosis (CAD) is to integrate CAD results into daily clinical practice so that it becomes a second reader to aid the radiologist's diagnosis. Integration of CAD and Hospital Information System (HIS), Radiology Information System (RIS) or PACS requires certain basic ingredients from Health Level 7 (HL7) standard for textual data, Digital Imaging and Communications in Medicine (DICOM) standard for images, and Integrating the Healthcare Enterprise (IHE) workflow profiles in order to comply with the Health Insurance Portability and Accountability Act (HIPAA) requirements to be a healthcare information system. Among the DICOM standards and IHE workflow profiles, DICOM Structured Reporting (DICOM-SR); and IHE Key Image Note (KIN), Simple Image and Numeric Report (SINR) and Post-processing Work Flow (PWF) are utilized in CAD-HIS/RIS/PACS integration. These topics with examples are presented in this chapter.

  8. Computer-Aided Modeling of Lipid Processing Technology

    DEFF Research Database (Denmark)

    Diaz Tovar, Carlos Axel

    2011-01-01

    the analysis, in terms of their design variables and their impact in the process behavior, of three lipid-related processes has been performed: the solvent recovery section of the extraction of crude soybean oil, the deodorization of palm oil, and the deacidification of soybean oil.......Vegetable oils and fats have an important role in human nutrition and in the chemical industry since they are a source of energy, fat-soluble vitamins, and now also in the production of renewable sources of energy. Nowadays as the consumer preferences for natural products and healthier foods...... increase along with growing interest in biofuels, the oleochemical industry faces in the upcoming years major challenges in terms of design and development of better products and more sustainable processes to make them. Computer-aided methods and tools for process synthesis, modeling and simulation...

  9. Decision trees and integrated features for computer aided mammographic screening

    Energy Technology Data Exchange (ETDEWEB)

    Kegelmeyer, W.P. Jr.; Groshong, B.; Allmen, M.; Woods, K.

    1997-02-01

    Breast cancer is a serious problem, which in the United States causes 43,000 deaths a year, eventually striking 1 in 9 women. Early detection is the only effective countermeasure, and mass mammography screening is the only reliable means for early detection. Mass screening has many shortcomings which could be addressed by a computer-aided mammographic screening system. Accordingly, we have applied the pattern recognition methods developed in earlier investigations of speculated lesions in mammograms to the detection of microcalcifications and circumscribed masses, generating new, more rigorous and uniform methods for the detection of both those signs. We have also improved the pattern recognition methods themselves, through the development of a new approach to combinations of multiple classifiers.

  10. A Computer-Aided Detection System for Digital Chest Radiographs

    Directory of Open Access Journals (Sweden)

    Juan Manuel Carrillo-de-Gea

    2016-01-01

    Full Text Available Computer-aided detection systems aim at the automatic detection of diseases using different medical imaging modalities. In this paper, a novel approach to detecting normality/pathology in digital chest radiographs is proposed. The problem tackled is complicated since it is not focused on particular diseases but anything that differs from what is considered as normality. First, the areas of interest of the chest are found using template matching on the images. Then, a texture descriptor called local binary patterns (LBP is computed for those areas. After that, LBP histograms are applied in a classifier algorithm, which produces the final normality/pathology decision. Our experimental results show the feasibility of the proposal, with success rates above 87% in the best cases. Moreover, our technique is able to locate the possible areas of pathology in nonnormal radiographs. Strengths and limitations of the proposed approach are described in the Conclusions.

  11. Peer Feedback in Computer Aided College English Writing Instruction

    Directory of Open Access Journals (Sweden)

    Ma Zhuo

    2016-01-01

    Full Text Available This study is to examine the acceptability of peer feedback in computer aided college English writing instruction. For the whole writing procedure, subjects in language labs were to take preparation, writing and evaluation stages, undergoing three editions suggested by peer feedbacks. For the first time reading, peers would comment on such general scale as subject and content of drafts, and the second focuses on specific items, for example the morphological, lexical and syntactical aspects, etc. To compare students’ attitudes towards the trial, before and after the experiment, Pre-Questionnaire and Post-Questionnaire were adopted to analyze differences. From the frequency of students’ views on ten statements, it is drawn that majority of subjects accept and enjoy the innovative writing process, since peer feedback is an essential and encouraging part for writing.

  12. The Computer Aided Aircraft-design Package (CAAP)

    Science.gov (United States)

    Yalif, Guy U.

    1994-01-01

    The preliminary design of an aircraft is a complex, labor-intensive, and creative process. Since the 1970's, many computer programs have been written to help automate preliminary airplane design. Time and resource analyses have identified, 'a substantial decrease in project duration with the introduction of an automated design capability'. Proof-of-concept studies have been completed which establish 'a foundation for a computer-based airframe design capability', Unfortunately, today's design codes exist in many different languages on many, often expensive, hardware platforms. Through the use of a module-based system architecture, the Computer aided Aircraft-design Package (CAAP) will eventually bring together many of the most useful features of existing programs. Through the use of an expert system, it will add an additional feature that could be described as indispensable to entry level engineers and students: the incorporation of 'expert' knowledge into the automated design process.

  13. Automatic computer-aided system of simulating solder joint formation

    Science.gov (United States)

    Zhao, Xiujuan; Wang, Chunqing; Zheng, Guanqun; Wang, Gouzhong; Yang, Shiqin

    1999-08-01

    One critical aspect in electronic packaging is the fatigue/creep-induced failure in solder interconnections, which is found to be highly dependent on the shape of solder joints. Thus predicting and analyzing the solder joint shape is warranted. In this paper, an automatic computer-aided system is developed to simulate the formation of solder joint and analyze the influence of the different process parameters on the solder joint shape. The developed system is capable of visually designing the process parameters and calculating the solder joint shape automatically without any intervention from the user. The automation achieved will enable fast shape estimation with the variation of process parameters without time consuming experiments, and the simulating system provides the design and manufacturing engineers an efficient software tools to design soldering process in design environment. Moreover, a program developed from the system can serve as the preprocessor for subsequent finite element joint analysis program.

  14. Computer-Aided Training and Quality Assessment of Creative Abilities

    Directory of Open Access Journals (Sweden)

    V. P. Pechnikov

    2015-01-01

    Full Text Available The article describes the training program that takes into account the laws of human mental activity. The peculiarity of this training is that it enables specialists to generate additional intellectual potentials. This potentials relate to various kinds of illogical (intuitive and hybrid (human-machine intelligences that are associated with the quality of professional and creative activity in future. Progress in trans-phenomenal functional systems of the brain is possible by means of special procedures and computer-based training programs.The article offers a logical system of computer-aided training. This system repeatedly compares its input and output data and uses a feedback as the innate human characteristic to obtain the final result.Computer-aided training can be implemented in analog and numeric form. The article deals with the numeric widely used MS Excel-based software. It provides tabular and graphic style visualization desirable for training.A specific technical program is used for training. It allows specialists to develop a reinforcement shell of square cell type of minimal weight. In designing various constraints can be considered.On the main page of MS Excel program there are input data tables, various forms of the cell, methods of its manufacturing, and a scale table. Coefficients needed for calculations are in the next tables. The next tables contain also technological and design limitations. The basic table enables us to vary the geometric complexes of the reinforcement shell. Using the tabular and graphical results of calculations an operator can define values of further steps (iterations. The operator’s aim is to design the shell of minimum weight for the shortest time or number of steps. There is number of counters using macros in the MS Excel tables to calculate the number of past iterations.

  15. Computer aided analysis, simulation and optimisation of thermal sterilisation processes.

    Science.gov (United States)

    Narayanan, C M; Banerjee, Arindam

    2013-04-01

    Although thermal sterilisation is a widely employed industrial process, little work is reported in the available literature including patents on the mathematical analysis and simulation of these processes. In the present work, software packages have been developed for computer aided optimum design of thermal sterilisation processes. Systems involving steam sparging, jacketed heating/cooling, helical coils submerged in agitated vessels and systems that employ external heat exchangers (double pipe, shell and tube and plate exchangers) have been considered. Both batch and continuous operations have been analysed and simulated. The dependence of del factor on system / operating parameters such as mass or volume of substrate to be sterilised per batch, speed of agitation, helix diameter, substrate to steam ratio, rate of substrate circulation through heat exchanger and that through holding tube have been analysed separately for each mode of sterilisation. Axial dispersion in the holding tube has also been adequately accounted for through an appropriately defined axial dispersion coefficient. The effect of exchanger characteristics/specifications on the system performance has also been analysed. The multiparameter computer aided design (CAD) software packages prepared are thus highly versatile in nature and they permit to make the most optimum choice of operating variables for the processes selected. The computed results have been compared with extensive data collected from a number of industries (distilleries, food processing and pharmaceutical industries) and pilot plants and satisfactory agreement has been observed between the two, thereby ascertaining the accuracy of the CAD softwares developed. No simplifying assumptions have been made during the analysis and the design of associated heating / cooling equipment has been performed utilising the most updated design correlations and computer softwares.

  16. A clinical trial of parecoxib sodium for pre-emptive analgesia in functional endoscopic sinus surgery%帕瑞昔布钠超前镇痛用于鼻内镜手术的临床观察

    Institute of Scientific and Technical Information of China (English)

    赵磊; 王天龙; 肖玮; 田丽娟

    2013-01-01

    We investigated the value of parecoxib sodium for pre-emptive analgesia of post-operation pain and inflammatory responses in patients undergoing functional endoscopic sinus surgery (FESS). Methods: Totally 40 patients of ASA Ⅰ ~ Ⅱ, aged 18 ~ 60 years, were randomly divided to two groups. They received parecoxib sodium 40 mg intravenously 30 min before operation, or saline 5 mL as control. Visual analogue scale (VAS) were recorded at postoperative 2, 6, 12, and 24 h. Venous blood samples were taken at 30 min before operation, the end of operation and postoperative 24 h to determine interleukin-6 ( IL-6 ) concentration. Results: VAS at postoperative 2 h was significantly lower in parecoxib sodium group than in control group. The postoperative serum IL-6 concentrations were significantly elevated from the baseline value in both groups. The serum IL-6 concentrations at postoperative 24 h were higher in control group than in parecoxib sodium group, but the difference was not statistically significant. Conclusion: Pre-incisional administration of 40mg parecoxib sodium reduces postoperative VAS of FESS patients without increasing adverse effects.%目的:研究帕瑞昔布钠超前镇痛对于功能内镜鼻窦手术(functional endoscopic sinus surgery,FESS)患者术后疼痛和炎症反应的影响.方法:选择FESS患者40例,ASA分级Ⅰ~Ⅱ级,年龄18 ~ 60岁,随机分为帕瑞昔布钠组和对照组.其中帕瑞昔布钠组患者在手术前30 min,静脉注射帕瑞昔布钠40 mg;对照组患者在手术前30 min,静注生理盐水5 mL作为安慰剂对照.记录术后2,6,12,24 h静息状态下视觉模拟评分(visual analogue scale,VAS).于手术前30 min、术毕即刻、术后24 h抽取静脉血,测定血浆白介素-6(in-terleukin-6,IL-6)水平.结果:帕瑞昔布钠组术后2 h VAS评分明显低于对照组.2组血浆IL-6水平术后均明显升高,术后24 h对照组血浆IL-6水平高于帕瑞昔布钠组,但无统计学意义.结论:功能

  17. 慢性鼻-鼻窦炎鼻内镜手术预后的影响因素分析%Analysis of the factors affecting the prognosis of functional endoscopic sinus surgery for chronic rhinosinusitis

    Institute of Scientific and Technical Information of China (English)

    徐艳红; 何刚; 黄定强; 朱玉博; 石向阳

    2013-01-01

    目的 分析影响慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)功能性鼻内镜手术(functional endoscopic sinus surgery,FESS)预后的因素,为术前评价和术后治疗提供依据.方法 对有手术指征的59例CRS患者行术前检查,记录视觉类比法评分(visual analog scale,VAS)、鼻内镜评分、性别、年龄、血嗜酸性粒细胞数目以及是否合并哮喘、息肉资料.患者术后随访1年以上,共5次,每次随诊记录患者VAS及鼻内镜评分,根据结果判断手术预后,并进行影响预后的因素分析.结果 血嗜酸性粒细胞数目增高,伴有哮喘的患者FESS预后差,其他因素不是影响FESS术后预后情况的主要因素.结论 在所记录的指标中,血嗜酸性粒细胞数目增高,伴有哮喘评估手术效果意义重大,伴有息肉的CRS并不引起更差的手术效果,提示传统意义上的CRS的分型可能并不合理.%Objective To analyze the factors affecting the prognosis of functional endoscopic sinus surgery(FESS)for chronic rhinosinusitis( CRS)in order to provide the basis for preoperative evaluation and postoperative treatment. Methods The preoperative examinations were performed for fifty-nine patients with CRS including scores of visual analog scale (VAS) ,and nasal endoscopy, and gender,age,number of eosnophils,and whether or not combinated with asthma or nasal polyp. After the operation,the patients were fol-lowed-up for five times during the period of one year. The scores of VAS and nasal endoscopy were recorded. Factors affecting the prognosis were statistically analyzed. Results The increased number of blood esonophils and the combination with asthma had a negative effect on the prognosis of the operation while the other factors did not. Conclusions The number of blood esonophils and CRS combined with asthma are the major factors that affect the prognosis of FESS while CRS combined with nasal polyp had no significant effect. Therefore, the traditional classification of

  18. Discussion of sevoflurane in deliberate hypotension of hypertension patients for endoscopic sinus surgery%七氟烷控制性降压在高血压患者鼻内窥镜手术的探讨

    Institute of Scientific and Technical Information of China (English)

    张继如; 张焰; 朱小莲

    2011-01-01

    Objective To investigate the feasibility and security of Sevoflurane in deliberate hypotension of hypertension patients for endoscopic sinus surgery(ESS). Methods Sixty-four patients of non-coagulation dysfunction with ASA I ~ Ⅱ undergoing ESS were randomly divided into urapidil group(A group), nitroglycerin group(B group), nitroglycerin combined with esmolol group(C group)and sevoflurane group(D group), 16 cases of each group. Controlled hypotension patients make the MAP preoperative blood pressure about 65 %~ 70 %, recorded the observed changes, and control. Results Group A, patients deliberate hypotension were smooth,but a small step down rate; in Group B, Patients'heart rate were obviously increased after deliberate hypotension(P<0.01);in Group C,the effect of deliberate hypotension was exact, but to the operation process was cumbersome;in Group D the use was simple,the effect of deliberate hypotension and analgesic was exact; the opening time and extubation time of patients in four group after operation didn't changed significantly(P>0.01). Patients'myocardial oxygen consumption were decreased obviously in all groups(P<0.01). Conclusion Sevoflurane combine with intravenous anesthesia in deliberate hypotension of hypertension patients for endoscopic sinus surgery can provide perfect analgesia and reduce the blood loss and operation time significantly reduce without affecting the awakenness,and which is a good method of controlled hypotension.%目的 探讨七氟烷控制性降压在高血压患者鼻内窥镜手术(ESS)中应用的合理性和可行性.方法 选择择期ESS患者64例,ASA I~Ⅱ级,无凝血功能障碍,随机分为乌拉地尔组(A组)、硝酸甘油组(B组)、硝酸甘油伍用艾司洛尔组(C组)和七氟烷组(D组),每组16例.降压组术中使MAP控制在术前基础血压的65%~70%,记录各观察指标变化,并进行对照分析.结果 A组降压后平稳,但降压幅度小;B组降压

  19. The application of computer-aided technologies in automotive styling design

    Science.gov (United States)

    Zheng, Ze-feng; Zhang, Ji; Zheng, Ying

    2012-04-01

    In automotive industry, outline design is its life and creative design is its soul indeed. Computer-aided technology has been widely used in the automotive industry and more and more attention has been paid. This paper chiefly introduce the application of computer-aided technologies including CAD, CAM and CAE, analyses the process of automotive structural design and describe the development tendency of computer-aided design.

  20. Converting Between PLY and Ballistic Research Laboratory-Computer-Aided Design (BRL-CAD) File Formats

    Science.gov (United States)

    2015-02-01

    Converting Between PLY and Ballistic Research Laboratory–Computer-Aided Design (BRL- CAD ) File Formats by Rishub Jain ARL-CR-0760...0760 February 2015 Converting Between PLY and Ballistic Research Laboratory–Computer-Aided Design (BRL- CAD ) File Formats Rishub Jain US...and Ballistic Research Laboratory–Computer-Aided Design (BRL- CAD ) File Formats 5a. CONTRACT NUMBER W911NF-10-2-0076 5b. GRANT NUMBER 5c. PROGRAM

  1. Target Impact Detection Algorithm Using Computer-aided Design (CAD) Model Geometry

    Science.gov (United States)

    2014-09-01

    UNCLASSIFIED AD-E403 558 Technical Report ARMET-TR-13024 TARGET IMPACT DETECTION ALGORITHM USING COMPUTER-AIDED DESIGN ( CAD ...DETECTION ALGORITHM USING COMPUTER-AIDED DESIGN ( CAD ) MODEL GEOMETRY 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...This report documents a method and algorithm to export geometry from a three-dimensional, computer-aided design ( CAD ) model in a format that can be

  2. An exploratory study of microbial diversity in sinus infections of cystic fibrosis patients by molecular methods

    DEFF Research Database (Denmark)

    Rudkjøbing, Vibeke Børsholt; Aanaes, Kasper; Wolff, Tine Yding;

    2014-01-01

    BACKGROUND: For the first time microorganisms in CF sinuses are investigated by molecular methods in response to an absence of anaerobes in CF sinus samples during a two-year period at the Copenhagen CF center. METHODS: Endoscopic sinus surgery was performed in 19 CF patients. DNA from intact...

  3. Application of disposable laryngeal mask airway in functional endoscopic sinus surgery%喉罩通气在鼻内窥镜手术麻醉中的应用

    Institute of Scientific and Technical Information of China (English)

    姚东旭; 陈继彬

    2012-01-01

    Objective To assess the clinical performance of disposable laryngeal mask airway (LMA) by comparing the effect on hemodynamics and respiratory mechanics of LMA with endotracheal intubation (ETT) in functional endoscopic sinus surgery. Methods 40 patients undergoing functional endoscopic sinus surgeries were enrolled in the study. They were evenly and randomly assigned into LMA group and ETT group who were either applied with LMA or ETT after induction of general anesthesia. Mean arterial pressure (MAP), heart rate (HR) and oxygen saturation (SpO2) were recorded before and after the induction of anesthesia, as well as right after the inserting and removal of ETT or LMA. Parameters for respiratory mechanics including peak inspiratory pressure (PIP), plateau airway pressure (Pplateau), mean airway pressure (Pmean), positive end expiratory pressure (PEEP), peak inspiratory flow (FImax), peak expiratory flow (FEmax) were also recorded at 5, 15 and 30 minutes after induction. Meanwhile, the first-time insertion success rate and complications up to 24 hours after extubation for LMA and ETT were compared as well. Results The MAP and HR at each recorded points in LMA group were significantly lower than those in ETT group (P<0. 05) , and the PIP, Pplateau, Pmean and FEmax at each recorded points in LAM group were also significantly lower compared with those in ETT group (P<0. 05) .Complications such as coughing, pharyngeal pain and muscular soreness were much less noted in LMA group than in TT group (P<0. 05) . Conclusions The disposable laryngeal mask airway is much safer than endotracheal intubation and may be an effective device for positive pressure ventilation in patients requiring functional endoscopic sinus surgery.%目的 比较一次性喉罩与气管插管用于鼻内窥镜手术麻醉中对血流动力学及呼吸动力学的影响.方法 将拟在全身麻醉下择期行鼻内窥镜手术的40例患者随机分为喉罩组(LMA)和气管插管组(TT),每组各20

  4. Sinus Tumors

    Science.gov (United States)

    ... scan of a patient with a sinus cancer (esthesioneuroblastoma) on the patient's right side (left side of ... mucoepidermoid carcinoma, melanoma, olfactory neuroblastoma (also known as esthesioneuroblastoma), sarcoma, and lymphoma. Malignant lesions from other body ...

  5. Tooth in Ethmoid Sinus: A Case Report

    Directory of Open Access Journals (Sweden)

    Tayebe Kazemei

    2009-09-01

    Full Text Available Ectopic eruption of teeth occurs in a variety of locations.Commonly seen in palate and maxillary sinus, they have alsobeen reported in nasal cavity, orbit, mandibular condyle,coronoid process, and facial skin.Here, we report a rare case of recurrent sinusitis caused byectopic tooth in right ethmoid sinus and successful endoscopicremoval of it. The symptoms of the patient disappeared aftersurgery. Such case has not been yet reported in the Englishliterature.Ectopic tooth is an uncommon cause of sinusitis. It shouldbe considered in patients presenting with recurrent sinusitis unresponsiveto medical treatment. Computed tomography of thesinuses is the modality of choice for diagnosis. Endoscopic sinussurgery is the best method for management of such cases.

  6. 鼻内镜下不同手术径路额窦开放术的临床分析%A Clinical analyze of different approaches of transnasal endoscopic frontal sinus surgery

    Institute of Scientific and Technical Information of China (English)

    周立辉; 葛前进; 王戬

    2013-01-01

    目的 探讨不同手术径路额窦开放术的疗效,总结额窦开放的策略及技巧,以提高额窦开放的成功率.方法 回顾分析我科2003年9月~2010年9月间经鼻内镜行额窦开放术496例(718侧),其中钩突径路额窦开放术232例(348侧),鼻丘径路额窦开放术264例(370侧),术后随访6~18个月.比较术中术后并发症及术后疗效.结果 ①两组患者均随访6~18个月,平均随访12个月.钩突径路组有放率91.67%,鼻丘径路组有效率92.70%,两组比较差异无统计学意义(x2=0.268,P>0.05):②手术并发症:钩突径路组脑脊液鼻漏1例(1侧),筛前动脉损伤2例(2侧),单纯眶周青紫5例(6侧),术后窦口狭窄7例(10侧);鼻丘径路组鼻泪管损伤1例(1侧),单纯眶周青紫5例(7侧),术后窦口狭窄8例(9侧).结论 以钩突上端和以鼻丘气房为标志均能准确定位额窦开口,并行额窦开放术,二者各有其优点,可以依据鼻窦解剖,术者经验来选择.当然,手术中如能将两者有机结合应用则更好.%Objective To observe therapeutic effect of transnasal endoscopic frontal sinus (FS) surgeries with differential surgical approaches,summarize the skills of FS opening,and improve its success rate.Methods 496 patients (718 sides) with transnasal endoscopic FS surgery from 2003 to 2010 were retrospectively studied,which were performed in 232 patients (348 sides) of surgical procedure through uncinate process and 264 patients (370 sides) were treated through agger nasi cell.The intra-operative complications are compared,and the postoperative complications and efficacy were also analyzed during the follow-up of 6 to 18 months.Results They were followed-up 6~18 months,average 12 months.The effective rates of surgical procedure through uncinate process and agger nasi cell are 91.67% and 92.70%,respectively.The difference between the two rates is not statistically significant x2=0.268,P>0.05).Surgical complications:1 case (1 side) with

  7. Fracture resistance of computer-aided design/computer-aided manufacturing-generated composite resin-based molar crowns.

    Science.gov (United States)

    Harada, Akio; Nakamura, Keisuke; Kanno, Taro; Inagaki, Ryoichi; Örtengren, Ulf; Niwano, Yoshimi; Sasaki, Keiichi; Egusa, Hiroshi

    2015-04-01

    The aim of this study was to investigate whether different fabrication processes, such as the computer-aided design/computer-aided manufacturing (CAD/CAM) system or the manual build-up technique, affect the fracture resistance of composite resin-based crowns. Lava Ultimate (LU), Estenia C&B (EC&B), and lithium disilicate glass-ceramic IPS e.max press (EMP) were used. Four types of molar crowns were fabricated: CAD/CAM-generated composite resin-based crowns (LU crowns); manually built-up monolayer composite resin-based crowns (EC&B-monolayer crowns); manually built-up layered composite resin-based crowns (EC&B-layered crowns); and EMP crowns. Each type of crown was cemented to dies and the fracture resistance was tested. EC&B-layered crowns showed significantly lower fracture resistance compared with LU and EMP crowns, although there was no significant difference in flexural strength or fracture toughness between LU and EC&B materials. Micro-computed tomography and fractographic analysis showed that decreased strength probably resulted from internal voids in the EC&B-layered crowns introduced by the layering process. There was no significant difference in fracture resistance among LU, EC&B-monolayer, and EMP crowns. Both types of composite resin-based crowns showed fracture loads of >2000 N, which is higher than the molar bite force. Therefore, CAD/CAM-generated crowns, without internal defects, may be applied to molar regions with sufficient fracture resistance. © 2015 Eur J Oral Sci.

  8. Micrometric precision of prosthetic dental crowns obtained by optical scanning and computer-aided designing/computer-aided manufacturing system

    Science.gov (United States)

    das Neves, Flávio Domingues; de Almeida Prado Naves Carneiro, Thiago; do Prado, Célio Jesus; Prudente, Marcel Santana; Zancopé, Karla; Davi, Letícia Resende; Mendonça, Gustavo; Soares, Carlos José

    2014-08-01

    The current study evaluated prosthetic dental crowns obtained by optical scanning and a computer-aided designing/computer-aided manufacturing system using micro-computed tomography to compare the marginal fit. The virtual models were obtained with four different scanning surfaces: typodont (T), regular impressions (RI), master casts (MC), and powdered master casts (PMC). Five virtual models were obtained for each group. For each model, a crown was designed on the software and milled from feldspathic ceramic blocks. Micro-CT images were obtained for marginal gap measurements and the data were statistically analyzed by one-way analysis of variance followed by Tukey's test. The mean vertical misfit was T=62.6±65.2 μm; MC=60.4±38.4 μm; PMC=58.1±38.0 μm, and RI=89.8±62.8 μm. Considering a percentage of vertical marginal gap of up to 75 μm, the results were T=71.5%, RI=49.2%, MC=69.6%, and PMC=71.2%. The percentages of horizontal overextension were T=8.5%, RI=0%, MC=0.8%, and PMC=3.8%. Based on the results, virtual model acquisition by scanning the typodont (simulated mouth) or MC, with or without powder, showed acceptable values for the marginal gap. The higher result of marginal gap of the RI group suggests that it is preferable to scan this directly from the mouth or from MC.

  9. The application of endoscopic sinus joint laryngoscope in laryngeal microsurgery%鼻内镜联合支撑喉镜在喉显微手术中的应用

    Institute of Scientific and Technical Information of China (English)

    肖阳; 袁毅; 陈景莲

    2013-01-01

    目的 观察鼻内镜联合支撑喉镜在喉显微手术中的应用效果.方法 将68例喉部病变患者随机分为多镜联用组(34例)和单喉镜组(34例),喉显微组在鼻内镜联合支撑喉镜下进行喉显微手术,单喉镜组仅选择使用在支撑喉镜下进行喉显微手术.比较两组疗效和手术情况.结果 多镜联用组总有效率为97.06%,明显高于单喉镜组的85.30%(x2=4.031,P<0.05);多镜联用组手术情况和并发症及复发率情况较,均优于单喉镜组(均P<0.05).结论 鼻内镜联合支撑喉镜在喉显微手术中有扩大手术视野范围和增加病灶区清晰度的功能,且具有对患者的创伤性小、少并发症、复发率低、操作简便、精确度高等优点.%Objective To observe the effect applicated of endoscopic sinus joint laryngoscope in laryngeal microsurgery.Methods 68 patients with laryngeal lesions were randomly divided into the multi-mirror combination group (34 cases) and the single laryngoscope group (34 cases).The multi-mirror combination group was taken with laryngeal microsurgery under endoscopic Joint laryngoscope.The single laryngoscope group was only taken with laryngeal microsurgery under laryngoscope.The efficacy and surgical situation of the two groups were compared.Results The total effective rate of the multi-mirror combination group was 97.06%,which was significantly higher than that of the single-laryngoscope group (85.30%) (x2 =4.031,P < 0.05).Compared with the case of surgery and complications and recurrence rate,the multi-mirror combination group was superior to the single laryngoscope group (all P < 0.05).Conclusion The endoscopic joint laryngoscope has the function of expanding the scope of the operative field and increasing the focus and clarity,and also has the advantages of small traumatic for patients,fewer complications,low recurrence rate,easy operation and high accuracy.

  10. Osteoma of the skull base and sinuses

    NARCIS (Netherlands)

    C. Georgalas; J. Goudakos; W.J. Fokkens

    2011-01-01

    Osteomata of the frontal and ethmoid sinuses have traditionally been surgically removed via external approaches. However, endoscopic techniques have increasingly been used for the surgical management of selected cases. Advances in visualization and instrumentation, as well as the excellent access pr

  11. Sinusitis (For Teens)

    Science.gov (United States)

    ... Can I Help Someone Who's Being Bullied? Volunteering Sinusitis KidsHealth > For Teens > Sinusitis Print A A A ... times, but it's usually not severe. What Is Sinusitis? Sinusitis is the medical term for inflammation (irritation ...

  12. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... are obstructed and the best imaging modality for sinusitis. Tell your doctor if there’s a possibility you ... the sinuses is primarily used to: help diagnose sinusitis . evaluate sinuses that are filled with fluid or ...

  13. Teaching Computer-Aided Design of Fluid Flow and Heat Transfer Engineering Equipment.

    Science.gov (United States)

    Gosman, A. D.; And Others

    1979-01-01

    Describes a teaching program for fluid mechanics and heat transfer which contains both computer aided learning (CAL) and computer aided design (CAD) components and argues that the understanding of the physical and numerical modeling taught in the CAL course is essential to the proper implementation of CAD. (Author/CMV)

  14. [The automatic iris map overlap technology in computer-aided iridiagnosis].

    Science.gov (United States)

    He, Jia-feng; Ye, Hu-nian; Ye, Miao-yuan

    2002-11-01

    In the paper, iridology and computer-aided iridiagnosis technologies are briefly introduced and the extraction method of the collarette contour is then investigated. The iris map can be overlapped on the original iris image based on collarette contour extraction. The research on collarette contour extraction and iris map overlap is of great importance to computer-aided iridiagnosis technologies.

  15. Computer-aided Diagnosis: How to Move from the Laboratory to the Clinic.

    NARCIS (Netherlands)

    Ginneken, B. van; Schaefer-Prokop, C.M.; Prokop, M.

    2011-01-01

    Computer-aided diagnosis (CAD), encompassing computer-aided detection and quantification, is an established and rapidly growing field of research. In daily practice, however, most radiologists do not yet use CAD routinely. This article discusses how to move CAD from the laboratory to the clinic. The

  16. Enabling Lean Design Through Computer Aided Synthesis: The Injection Moulding Cooling Case

    NARCIS (Netherlands)

    Jauregui Becker, Juan M.; Wits, Wessel W.

    2015-01-01

    This paper explores the application of Computer Aided Synthesis (CAS) to support the implementation of Set-Based Concurrent Engineering (SBCE) and Just In Time Decision Making (JIT-DM), which are considered as two of the cornerstones of the Lean Design method. Computer Aided Synthesis refers to a ne

  17. XPLANE, a Generative Computer Aided Process Planning System for Part Manufacturing

    NARCIS (Netherlands)

    Erve, van 't A.H.

    1986-01-01

    This paper reports on the development of XPLANE, a generative computer aided process planning system for part manufacturing. Described is its position and functioning as a part of a more extended computer aided manufacturing system that includes a link to CAD systems, as well as systems for computer

  18. CART V: recent advancements in computer-aided camouflage assessment

    Science.gov (United States)

    Müller, Thomas; Müller, Markus

    2011-05-01

    In order to facilitate systematic, computer aided improvements of camouflage and concealment assessment methods, the software system CART (Camouflage Assessment in Real-Time) was built up for the camouflage assessment of objects in multispectral image sequences (see contributions to SPIE 2007-2010 [1], [2], [3], [4]). It comprises a semi-automatic marking of target objects (ground truth generation) including their propagation over the image sequence and the evaluation via user-defined feature extractors as well as methods to assess the object's movement conspicuity. In this fifth part in an annual series at the SPIE conference in Orlando, this paper presents the enhancements over the recent year and addresses the camouflage assessment of static and moving objects in multispectral image data that can show noise or image artefacts. The presented methods fathom the correlations between image processing and camouflage assessment. A novel algorithm is presented based on template matching to assess the structural inconspicuity of an object objectively and quantitatively. The results can easily be combined with an MTI (moving target indication) based movement conspicuity assessment function in order to explore the influence of object movement to a camouflage effect in different environments. As the results show, the presented methods contribute to a significant benefit in the field of camouflage assessment.

  19. Electromagnetic tracking for abdominal interventions in computer aided surgery.

    Science.gov (United States)

    Zhang, Hui; Banovac, Filip; Lin, Ralph; Glossop, Neil; Wood, Bradford J; Lindisch, David; Levy, Elliot; Cleary, Kevin

    2006-05-01

    Electromagnetic tracking has great potential for assisting physicians in precision placement of instruments during minimally invasive interventions in the abdomen, since electromagnetic tracking is not limited by the line-of-sight restrictions of optical tracking. A new generation of electromagnetic tracking has recently become available, with sensors small enough to be included in the tips of instruments. To fully exploit the potential of this technology, our research group has been developing a computer aided, image-guided system that uses electromagnetic tracking for visualization of the internal anatomy during abdominal interventions. As registration is a critical component in developing an accurate image-guided system, we present three registration techniques: 1) enhanced paired-point registration (time-stamp match registration and dynamic registration); 2) orientation-based registration; and 3) needle shape-based registration. Respiration compensation is another important issue, particularly in the abdomen, where respiratory motion can make precise targeting difficult. To address this problem, we propose reference tracking and affine transformation methods. Finally, we present our prototype navigation system, which integrates the registration, segmentation, path-planning and navigation functions to provide real-time image guidance in the clinical environment. The methods presented here have been tested with a respiratory phantom specially designed by our group and in swine animal studies under approved protocols. Based on these tests, we conclude that our system can provide quick and accurate localization of tracked instruments in abdominal interventions, and that it offers a user-friendly display for the physician.

  20. [Computer-aided electronic prescribing in Spanish hospitals].

    Science.gov (United States)

    Rubio Fernández, M; Aldaz Francés, R; García Gómez, C; Valladolid Walsh, A

    2005-01-01

    To describe electronic prescribing in a sample of Spanish hospitals and activities derived from its implementation in Hospital Pharmacy Departments, software features and acceptance. A survey that included data related to program implantation and performance in hospitals with diverse characteristics was designed. It was posted at the Sociedad Española de Farmacia Hospitalaria website for a 6-month period and completed by phone. A total of 47 hospitals answered the survey. 13 (27.7%) had electronic prescribing systems, and of these, 8 of them had more than 75% of beds included in the system. In 15 (31.9%) hospitals that did not have it, its implementation was in project in the near future. Software applications used in this new health technology were not homogeneous, while integration of applications that facilitate Pharmaceutical Care tasks was infrequent. In 61.5% of the hospitals with electronic prescribing, transcription used to be the pharmacist s task. In 92.3% of these hospitals, order validation is currently carried out by pharmacists. The degree of satisfaction with the system was rated as good or very good by 92.3% of pharmacists. Computer-aided electronic prescribing appears to be a helpful tool for restructuring Department organization and investing time in new activities. A more ambitious and effective approach to clinical activities will therefore be possible. System optimization requires taking into account factors such as worker time investment, since new activities will be developed, along with the need for training courses.

  1. Computer-Aided Vaccine Design: A Brief Report

    Directory of Open Access Journals (Sweden)

    R Ghasemi Khorasgani

    2012-09-01

    Full Text Available Background: Although the conventional vaccines have been instrumented in the incidence of many infectious diseases, the advances in genetic engineering and bioinformatics have provided the opportunity for developing improved and new vaccines.Methods: Reverse vaccinology was pioneered by a group of researchers investigating development of a vaccine against serogroup B Neisseria meningitidis. Reverse vaccinology analyzes the entire genome of a pathogen with the aid of computational programs to identify potentially antigenic extracellular proteins.Results: Using this method for Neisseria meningitidis genome analysis, 600 secretory or surface-exposed proteins were identified and, subsequently, 350 proteins were expressed and purified. Finally, seven proteins capable of activating the immune system against a range of strains were identified.Conclusion: Improved computational techniques are now able to provide researchers with high-confidence predictions for complex biological characteristics. This will herald a move to computer-aided biotechnology in which time-consuming and expensive large-scale experimental approaches are progressively replaced by functional bioinformatic investigations.

  2. ARCHITECTURE OF WEB BASED COMPUTER-AIDED MANUFACTURING SYSTEM

    Directory of Open Access Journals (Sweden)

    N. E. Filyukov

    2014-09-01

    Full Text Available The paper deals with design of a web-based system for Computer-Aided Manufacturing (CAM. Remote applications and databases located in the "private cloud" are proposed to be the basis of such system. The suggested approach contains: service - oriented architecture, using web applications and web services as modules, multi-agent technologies for implementation of information exchange functions between the components of the system and the usage of PDM - system for managing technology projects within the CAM. The proposed architecture involves CAM conversion into the corporate information system that will provide coordinated functioning of subsystems based on a common information space, as well as parallelize collective work on technology projects and be able to provide effective control of production planning. A system has been developed within this architecture which gives the possibility for a rather simple technological subsystems connect to the system and implementation of their interaction. The system makes it possible to produce CAM configuration for a particular company on the set of developed subsystems and databases specifying appropriate access rights for employees of the company. The proposed approach simplifies maintenance of software and information support for CAM subsystems due to their central location in the data center. The results can be used as a basis for CAM design and testing within the learning process for development and modernization of the system algorithms, and then can be tested in the extended enterprise.

  3. A digital patient for computer-aided prosthesis design.

    Science.gov (United States)

    Colombo, Giorgio; Facoetti, Giancarlo; Rizzi, Caterina

    2013-04-06

    This article concerns the design of lower limb prosthesis, both below and above knee. It describes a new computer-based design framework and a digital model of the patient around which the prosthesis is designed and tested in a completely virtual environment. The virtual model of the patient is the backbone of the whole system, and it is based on a biomechanical general-purpose model customized with the patient's characteristics (e.g. anthropometric measures). The software platform adopts computer-aided and knowledge-guided approaches with the goal of replacing the current development process, mainly hand made, with a virtual one. It provides the prosthetics with a set of tools to design, configure and test the prosthesis and comprehends two main environments: the prosthesis modelling laboratory and the virtual testing laboratory. The first permits the three-dimensional model of the prosthesis to be configured and generated, while the second allows the prosthetics to virtually set up the artificial leg and simulate the patient's postures and movements, validating its functionality and configuration. General architecture and modelling/simulation tools for the platform are described as well as main aspects and results of the experimentation.

  4. Computer aided polymer design using multi-scale modelling

    Directory of Open Access Journals (Sweden)

    K. C. Satyanarayana

    2010-09-01

    Full Text Available The ability to predict the key physical and chemical properties of polymeric materials from their repeat-unit structure and chain-length architecture prior to synthesis is of great value for the design of polymer-based chemical products, with new functionalities and improved performance. Computer aided molecular design (CAMD methods can expedite the design process by establishing input-output relations between the type and number of functional groups in a polymer repeat unit and the desired macroscopic properties. A multi-scale model-based approach that combines a CAMD technique based on group contribution plus models for predicting polymer repeat unit properties with atomistic simulations for providing first-principles arrangements of the repeat units and for predictions of physical properties of the chosen candidate polymer structures, has been developed and tested for design of polymers with desired properties. A case study is used to highlight the main features of this multi-scale model-based approach for the design of a polymer-based product.

  5. The future of computer-aided sperm analysis

    Directory of Open Access Journals (Sweden)

    Sharon T Mortimer

    2015-01-01

    Full Text Available Computer-aided sperm analysis (CASA technology was developed in the late 1980s for analyzing sperm movement characteristics or kinematics and has been highly successful in enabling this field of research. CASA has also been used with great success for measuring semen characteristics such as sperm concentration and proportions of progressive motility in many animal species, including wide application in domesticated animal production laboratories and reproductive toxicology. However, attempts to use CASA for human clinical semen analysis have largely met with poor success due to the inherent difficulties presented by many human semen samples caused by sperm clumping and heavy background debris that, until now, have precluded accurate digital image analysis. The authors review the improved capabilities of two modern CASA platforms (Hamilton Thorne CASA-II and Microptic SCA6 and consider their current and future applications with particular reference to directing our focus towards using this technology to assess functional rather than simple descriptive characteristics of spermatozoa. Specific requirements for validating CASA technology as a semi-automated system for human semen analysis are also provided, with particular reference to the accuracy and uncertainty of measurement expected of a robust medical laboratory test for implementation in clinical laboratories operating according to modern accreditation standards.

  6. Computer-aided interpretation approach for optical tomographic images

    Science.gov (United States)

    Klose, Christian D.; Klose, Alexander D.; Netz, Uwe J.; Scheel, Alexander K.; Beuthan, Jürgen; Hielscher, Andreas H.

    2010-11-01

    A computer-aided interpretation approach is proposed to detect rheumatic arthritis (RA) in human finger joints using optical tomographic images. The image interpretation method employs a classification algorithm that makes use of a so-called self-organizing mapping scheme to classify fingers as either affected or unaffected by RA. Unlike in previous studies, this allows for combining multiple image features, such as minimum and maximum values of the absorption coefficient for identifying affected and not affected joints. Classification performances obtained by the proposed method were evaluated in terms of sensitivity, specificity, Youden index, and mutual information. Different methods (i.e., clinical diagnostics, ultrasound imaging, magnet resonance imaging, and inspection of optical tomographic images), were used to produce ground truth benchmarks to determine the performance of image interpretations. Using data from 100 finger joints, findings suggest that some parameter combinations lead to higher sensitivities, while others to higher specificities when compared to single parameter classifications employed in previous studies. Maximum performances are reached when combining the minimum/maximum ratio of the absorption coefficient and image variance. In this case, sensitivities and specificities over 0.9 can be achieved. These values are much higher than values obtained when only single parameter classifications were used, where sensitivities and specificities remained well below 0.8.

  7. Computer-aided simulation of the heat treatment

    Energy Technology Data Exchange (ETDEWEB)

    Arola, R.; Martikainen, H.; Virta, J. [Technical Research Centre of Finland, Espoo (Finland). Metallurgy Lab.

    1993-12-31

    Computer-aided simulation of the heat treatment of components and charges is examined. Existing programs for the simulation of heat treatment are reviewed. Test simulations including calculation of temperature, phase composition and stresses and strains during heating and cooling are performed with selected programs. The results of the simulations are compared with the results of heat treating experiments. Heat transfer during heating-up varies considerably between different treatments, components of the charge and surfaces of the component. Therefore, heat transfer data defined on the basis of the measurements has to be used in exact simulation instead of literature data. According to the simulation results non-uniform temperature distribution, plastic straining and residual stresses after heating can be formed in an AISI 316 bar heated up at the edge of a charge in a pit furnace. Permanent bending of these bars as a result of heating is not observed. In the oil quenching of a 42CrMo4 cylinder, where martensite and bainite are formed in austenite decomposition, the simulation results (especially amounts of phases and residual stresses) are crucially dependent on the TTT-diagram describing the kinetics of the phase transformations. Several TTT-diagrams for the steel grade are found, leading to different simulation results

  8. Orthodontics: computer-aided diagnosis and treatment planning

    Science.gov (United States)

    Yi, Yaxing; Li, Zhongke; Wei, Suyuan; Deng, Fanglin; Yao, Sen

    2000-10-01

    The purpose of this article is to introduce the outline of our newly developed computer-aided 3D dental cast analyzing system with laser scanning, and its preliminary clinical applications. The system is composed of a scanning device and a personal computer as a scanning controller and post processor. The scanning device is composed of a laser beam emitter, two sets of linear CCD cameras and a table which is rotatable by two-degree-of-freedom. The rotating is controlled precisely by a personal computer. The dental cast is projected and scanned with a laser beam. Triangulation is applied to determine the location of each point. Generation of 3D graphics of the dental cast takes approximately 40 minutes. About 170,000 sets of X,Y,Z coordinates are store for one dental cast. Besides the conventional linear and angular measurements of the dental cast, we are also able to demonstrate the size of the top surface area of each molar. The advantage of this system is that it facilitates the otherwise complicated and time- consuming mock surgery necessary for treatment planning in orthognathic surgery.

  9. COMPUTER-AIDED DETECTION OF ACINAR SHADOWS IN CHEST RADIOGRAPHS

    Directory of Open Access Journals (Sweden)

    Tao Xu

    2013-05-01

    Full Text Available Despite the technological advances in medical diagnosis, accurate detection of infectious tuberculosis (TB still poses challenges due to complex image features and thus infectious TB continues to be a public health problem of global proportions. Currently, the detection of TB is mainly conducted visually by radiologists examining chest radiographs (CXRs. To reduce the backlog of CXR examination and provide more precise quantitative assessment, computer-aided detection (CAD systems for potential lung lesions have been increasingly adopted and commercialized for clinical practice. CADs work as supporting tools to alert radiologists on suspected features that could have easily been neglected. In this paper, an effective CAD system aimed for acinar shadow regions detection in CXRs is proposed. This system exploits textural and photometric features analysis techniques which include local binary pattern (LBP, grey level co-occurrence matrix (GLCM and histogram of oriented gradients (HOG to analyze target regions in CXRs. Classification of acinar shadows using Adaboost is then deployed to verify the performance of a combination of these techniques. Comparative study in different image databases shows that the proposed CAD system delivers consistent high accuracy in detecting acinar shadows.

  10. Computer-Aided Experiment Planning toward Causal Discovery in Neuroscience.

    Science.gov (United States)

    Matiasz, Nicholas J; Wood, Justin; Wang, Wei; Silva, Alcino J; Hsu, William

    2017-01-01

    Computers help neuroscientists to analyze experimental results by automating the application of statistics; however, computer-aided experiment planning is far less common, due to a lack of similar quantitative formalisms for systematically assessing evidence and uncertainty. While ontologies and other Semantic Web resources help neuroscientists to assimilate required domain knowledge, experiment planning requires not only ontological but also epistemological (e.g., methodological) information regarding how knowledge was obtained. Here, we outline how epistemological principles and graphical representations of causality can be used to formalize experiment planning toward causal discovery. We outline two complementary approaches to experiment planning: one that quantifies evidence per the principles of convergence and consistency, and another that quantifies uncertainty using logical representations of constraints on causal structure. These approaches operationalize experiment planning as the search for an experiment that either maximizes evidence or minimizes uncertainty. Despite work in laboratory automation, humans must still plan experiments and will likely continue to do so for some time. There is thus a great need for experiment-planning frameworks that are not only amenable to machine computation but also useful as aids in human reasoning.

  11. A computer-aided diagnostic system for kidney disease

    Science.gov (United States)

    Jahantigh, Farzad Firouzi; Malmir, Behnam; Avilaq, Behzad Aslani

    2017-01-01

    Background Disease diagnosis is complicated since patients may demonstrate similar symptoms but physician may diagnose different diseases. There are a few number of investigations aimed to create a fuzzy expert system, as a computer aided system for disease diagnosis. Methods In this research, a cross-sectional descriptive study conducted in a kidney clinic in Tehran, Iran in 2012. Medical diagnosis fuzzy rules applied, and a set of symptoms related to the set of considered diseases defined. The input case to be diagnosed defined by assigning a fuzzy value to each symptom and then three physicians asked about each suspected diseases. Then comments of those three physicians summarized for each disease. The fuzzy inference applied to obtain a decision fuzzy set for each disease, and crisp decision values attained to determine the certainty of existence for each disease. Results Results indicated that, in the diagnosis of seven cases of kidney disease by examining 21 indicators using fuzzy expert system, kidney stone disease with 63% certainty was the most probable, renal tubular was at the lowest level with 15%, and other kidney diseases were at the other levels. The most remarkable finding of this study was that results of kidney disease diagnosis (e.g., kidney stone) via fuzzy expert system were fully compatible with those of kidney physicians. Conclusion The proposed fuzzy expert system is a valid, reliable, and flexible instrument to diagnose several typical input cases. The developed system decreases the effort of initial physical checking and manual feeding of input symptoms.

  12. Computer-Aided Sensor Development Focused on Security Issues

    Directory of Open Access Journals (Sweden)

    Andrzej Bialas

    2016-05-01

    Full Text Available The paper examines intelligent sensor and sensor system development according to the Common Criteria methodology, which is the basic security assurance methodology for IT products and systems. The paper presents how the development process can be supported by software tools, design patterns and knowledge engineering. The automation of this process brings cost-, quality-, and time-related advantages, because the most difficult and most laborious activities are software-supported and the design reusability is growing. The paper includes a short introduction to the Common Criteria methodology and its sensor-related applications. In the experimental section the computer-supported and patterns-based IT security development process is presented using the example of an intelligent methane detection sensor. This process is supported by an ontology-based tool for security modeling and analyses. The verified and justified models are transferred straight to the security target specification representing security requirements for the IT product. The novelty of the paper is to provide a patterns-based and computer-aided methodology for the sensors development with a view to achieving their IT security assurance. The paper summarizes the validation experiment focused on this methodology adapted for the sensors system development, and presents directions of future research.

  13. Computer aided lung cancer diagnosis with deep learning algorithms

    Science.gov (United States)

    Sun, Wenqing; Zheng, Bin; Qian, Wei

    2016-03-01

    Deep learning is considered as a popular and powerful method in pattern recognition and classification. However, there are not many deep structured applications used in medical imaging diagnosis area, because large dataset is not always available for medical images. In this study we tested the feasibility of using deep learning algorithms for lung cancer diagnosis with the cases from Lung Image Database Consortium (LIDC) database. The nodules on each computed tomography (CT) slice were segmented according to marks provided by the radiologists. After down sampling and rotating we acquired 174412 samples with 52 by 52 pixel each and the corresponding truth files. Three deep learning algorithms were designed and implemented, including Convolutional Neural Network (CNN), Deep Belief Networks (DBNs), Stacked Denoising Autoencoder (SDAE). To compare the performance of deep learning algorithms with traditional computer aided diagnosis (CADx) system, we designed a scheme with 28 image features and support vector machine. The accuracies of CNN, DBNs, and SDAE are 0.7976, 0.8119, and 0.7929, respectively; the accuracy of our designed traditional CADx is 0.7940, which is slightly lower than CNN and DBNs. We also noticed that the mislabeled nodules using DBNs are 4% larger than using traditional CADx, this might be resulting from down sampling process lost some size information of the nodules.

  14. Computer Aided Detection of SARS Based on Radiographs Data Mining.

    Science.gov (United States)

    Xuanyang, Xie; Yuchang, Gong; Shouhong, Wan; Xi, Li

    2005-01-01

    This paper introduces our work on how to use image mining techniques to detect SARS, the severe acute respiratory syndrome, automatically as the prototype of computer aided detection/diagnosis (CAD) system. Data used in this paper are digitalized PA(posterior anterior) X-ray images stored in the real-life picture archiving and communication system (PACS) of the 2nd Affiliation Hospital of Guangzhou Medical College. Association rule mining was applied first but results showed there was no significant difference between the locations of the lesions or infiltrate. Classification based on image textures was performed. A sample set contains both the pneumonia and SARS X-ray images was built in the first place. After modeling each sample by a feature vector, the sample set was partitioned to match the detection purpose: classification. Three methods were used: C4.5, neural network (NN) and CART. Final result shows that 70.94% SARS cases can be detected by CART. Data preparation, segmentation, feature extraction and data mining steps, with corresponding techniques are included in this paper. ROC charts and confusion matrix by all three methods are given and analyzed.

  15. Computer-Aided Sensor Development Focused on Security Issues.

    Science.gov (United States)

    Bialas, Andrzej

    2016-05-26

    The paper examines intelligent sensor and sensor system development according to the Common Criteria methodology, which is the basic security assurance methodology for IT products and systems. The paper presents how the development process can be supported by software tools, design patterns and knowledge engineering. The automation of this process brings cost-, quality-, and time-related advantages, because the most difficult and most laborious activities are software-supported and the design reusability is growing. The paper includes a short introduction to the Common Criteria methodology and its sensor-related applications. In the experimental section the computer-supported and patterns-based IT security development process is presented using the example of an intelligent methane detection sensor. This process is supported by an ontology-based tool for security modeling and analyses. The verified and justified models are transferred straight to the security target specification representing security requirements for the IT product. The novelty of the paper is to provide a patterns-based and computer-aided methodology for the sensors development with a view to achieving their IT security assurance. The paper summarizes the validation experiment focused on this methodology adapted for the sensors system development, and presents directions of future research.

  16. Computer-aided pattern classification system for dermoscopy images.

    Science.gov (United States)

    Abbas, Qaisar; Celebi, M Emre; Fondón, Irene

    2012-08-01

    Computer-aided pattern classification of melanoma and other pigmented skin lesions is one of the most important tasks for clinical diagnosis. To differentiate between benign and malignant lesions, the extraction of color, architectural order, symmetry of pattern and homogeneity (CASH) is a challenging task. In this article, a novel pattern classification system (PCS) based on the clinical CASH rule is presented to classify among six classes of patterns. The PCS system consists of the following five steps: transformation to the CIE L*a*b* color space, pre-processing to enhance the tumor region and removal of hairs, tumor-area segmentation, color and texture feature extraction, and finally, classification based on a multiclass support vector machine. The PCS system is tested on a total of 180 dermoscopic images. To test the performance of the PCS diagnostic classifier, the area under the receiver operating characteristics curve (AUC) is utilized. The proposed classifier achieved a sensitivity of 91.64%, specificity of 94.14%, and AUC of 0.948. The experimental results demonstrate that the proposed pattern classifier is highly accurate and classify between benign and malignant lesions into some extend. The PCS method is fully automatic and can accurately detect different patterns from dermoscopy images using color and texture properties. Additional pattern features can be included to investigate the impact of pattern classification based on the CASH rule. © 2011 John Wiley & Sons A/S.

  17. Computer-Aided Design of Nanocapsules for Therapeutic Delivery

    Directory of Open Access Journals (Sweden)

    Zeina Shreif

    2009-01-01

    Full Text Available The design of nanocapsules for targeted delivery of therapeutics presents many, often seemingly self-contradictory, constraints. An algorithm for predicting the physico-chemical characteristics of nanocapsule delivery and payload release using a novel all-atom, multiscale technique is presented. This computational method preserves key atomic-scale behaviours needed to make predictions of interactions of functionalized nanocapsules with the cell surface receptors, drug, siRNA, gene or other payload. We show how to introduce a variety of order parameters with distinct character to enable a multiscale analysis of a complex system. The all-atom formulation allows for the use of an interatomic force field, making the approach universal and avoiding recalibration with each new application. Alternatively, key parameters, which minimize the need for calibration, are also identified. Simultaneously, the methodology enables predictions of the supra-nanometer-scale behaviour, such as structural transitions and disassembly of the nanocapsule accompanying timed payload release or due to premature degradation. The final result is a Fokker–Planck equation governing the rate of stochastic payload release and structural changes and migration accompanying it. A novel “salt shaker” effect that underlies fluctuation-enhancement of payload delivery is presented. Prospects for computer-aided design of nanocapsule delivery system are discussed.

  18. The ultimate CASE (Computer-Aided Software Engineering) tool

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, J.K.

    1990-01-01

    The theory and practice of information engineering is being actively developed at Sandia National Laboratories. The main output of Sandia is information. Information is created, analyzed and distributed. It is the life blood of our design laboratory. The proper management of information will have a large, positive impact on staff productivity. In order to achieve the potential benefits of shared information a commonly understood approach is needed, and the approach must be implemented in a CASE (Computer-Aided Software Engineering) tool that spans the entire life cycle of information. The commonly understood approach used at Sandia is natural language. More specifically, it is a structured subset of English. Users and system developers communicate requirements and commitments that they both understand. The approach is based upon NIAM (Nijssen's Information Analysis Methodology). In the last three years four NIAM training classes have been given at Sandia. The classes were all at the introductory level, with the latest class last October having an additional seminar highlighting successful projects. The continued growth in applications using NIAM requires an advanced class. The class will develop an information model for the Ultimate CASE Tool.'' This paper presents the requirements that have been established for the Ultimate CASE Tool'' and presents initial models. 4 refs., 1 tab.

  19. Computer-Aided Experiment Planning toward Causal Discovery in Neuroscience

    Science.gov (United States)

    Matiasz, Nicholas J.; Wood, Justin; Wang, Wei; Silva, Alcino J.; Hsu, William

    2017-01-01

    Computers help neuroscientists to analyze experimental results by automating the application of statistics; however, computer-aided experiment planning is far less common, due to a lack of similar quantitative formalisms for systematically assessing evidence and uncertainty. While ontologies and other Semantic Web resources help neuroscientists to assimilate required domain knowledge, experiment planning requires not only ontological but also epistemological (e.g., methodological) information regarding how knowledge was obtained. Here, we outline how epistemological principles and graphical representations of causality can be used to formalize experiment planning toward causal discovery. We outline two complementary approaches to experiment planning: one that quantifies evidence per the principles of convergence and consistency, and another that quantifies uncertainty using logical representations of constraints on causal structure. These approaches operationalize experiment planning as the search for an experiment that either maximizes evidence or minimizes uncertainty. Despite work in laboratory automation, humans must still plan experiments and will likely continue to do so for some time. There is thus a great need for experiment-planning frameworks that are not only amenable to machine computation but also useful as aids in human reasoning. PMID:28243197

  20. Computer-aided drug design at Boehringer Ingelheim

    Science.gov (United States)

    Muegge, Ingo; Bergner, Andreas; Kriegl, Jan M.

    2016-09-01

    Computer-Aided Drug Design (CADD) is an integral part of the drug discovery endeavor at Boehringer Ingelheim (BI). CADD contributes to the evaluation of new therapeutic concepts, identifies small molecule starting points for drug discovery, and develops strategies for optimizing hit and lead compounds. The CADD scientists at BI benefit from the global use and development of both software platforms and computational services. A number of computational techniques developed in-house have significantly changed the way early drug discovery is carried out at BI. In particular, virtual screening in vast chemical spaces, which can be accessed by combinatorial chemistry, has added a new option for the identification of hits in many projects. Recently, a new framework has been implemented allowing fast, interactive predictions of relevant on and off target endpoints and other optimization parameters. In addition to the introduction of this new framework at BI, CADD has been focusing on the enablement of medicinal chemists to independently perform an increasing amount of molecular modeling and design work. This is made possible through the deployment of MOE as a global modeling platform, allowing computational and medicinal chemists to freely share ideas and modeling results. Furthermore, a central communication layer called the computational chemistry framework provides broad access to predictive models and other computational services.

  1. The promise of computer aided detection in digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Roehrig, Jimmy E-mail: jimmy@enrico.r2tech.com; Castellino, Ronald A. E-mail: castellr@mskcc.org

    1999-07-01

    Computer-aided detection (CAD) is a new technology now being implemented in many clinics to reduce the false negative rate in mammography screening. A large clinical study has been completed which shows that a substantial false negative (miss) rate exists in screening mammography, a significant fraction of the missed cancers are not subtle, and CAD has high sensitivity to these missed cancers. Full field digital mammography is now coming on the scene, but has not yet been proven in clinical practice. The authors believe that full acceptance of the new digital technology depends not merely on demonstrations of 'substantial equivalence' to film-screen technology, but rather on more complete exploitation of the unique advantages of digital technology, and that CAD can play a key role. These advantages derive from CAD's ability to quickly (in near real-time) perform analytical computations on digital information that is not readily available to the radiologist until after the cost of film-processing has occurred.

  2. A handheld computer-aided diagnosis system and simulated analysis

    Science.gov (United States)

    Su, Mingjian; Zhang, Xuejun; Liu, Brent; Su, Kening; Louie, Ryan

    2016-03-01

    This paper describes a Computer Aided Diagnosis (CAD) system based on cellphone and distributed cluster. One of the bottlenecks in building a CAD system for clinical practice is the storage and process of mass pathology samples freely among different devices, and normal pattern matching algorithm on large scale image set is very time consuming. Distributed computation on cluster has demonstrated the ability to relieve this bottleneck. We develop a system enabling the user to compare the mass image to a dataset with feature table by sending datasets to Generic Data Handler Module in Hadoop, where the pattern recognition is undertaken for the detection of skin diseases. A single and combination retrieval algorithm to data pipeline base on Map Reduce framework is used in our system in order to make optimal choice between recognition accuracy and system cost. The profile of lesion area is drawn by doctors manually on the screen, and then uploads this pattern to the server. In our evaluation experiment, an accuracy of 75% diagnosis hit rate is obtained by testing 100 patients with skin illness. Our system has the potential help in building a novel medical image dataset by collecting large amounts of gold standard during medical diagnosis. Once the project is online, the participants are free to join and eventually an abundant sample dataset will soon be gathered enough for learning. These results demonstrate our technology is very promising and expected to be used in clinical practice.

  3. Microbiologia dos seios maxilar e etmoidal em pacientes com rinossinusite crônica submetidos à cirurgia funcional endoscópica dos seios paranasais Microbiology of the maxillary and ethmoid sinuses in patients with chronic rhinosinusitis submitted to functional endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    Josiane Faria de Aguiar Nigro

    2006-04-01

    rhinosinusitis and with indication of functional endoscopic sinus surgery. MATERIALS AND METHODS: During surgery, we collected secretion and/or fragments of maxillary and/or ethmoid sinus mucosa from 41 patients to perform Gram stain, fungus direct research, aerobe and anaerobe microorganism culture and fungus culture. RESULTS: We identified the presence of aerobe microorganisms in 21 patients (51.2%, anaerobe microorganisms in 16 (39% and fungus in 1 (2.4%. In the studied population, only 12 patients (29.2% presented microorganisms considered pathogenic when analyzed together with the semi-quantitative leukocyte count. Staphylococcus coagulase-negative and Staphylococcus aureus were the most frequent microorganisms found, in 5 (12.18% and in 4 (9.75% patients respectively. CONCLUSION: This study reveals that Staphylococcus coagulase-negative and Staphylococcus aureus were the most frequent microorganisms isolated from patients with chronic rhinosinusitis.

  4. Computer-aided colorectal tumor classification in NBI endoscopy using local features.

    Science.gov (United States)

    Tamaki, Toru; Yoshimuta, Junki; Kawakami, Misato; Raytchev, Bisser; Kaneda, Kazufumi; Yoshida, Shigeto; Takemura, Yoshito; Onji, Keiichi; Miyaki, Rie; Tanaka, Shinji

    2013-01-01

    An early detection of colorectal cancer through colorectal endoscopy is important and widely used in hospitals as a standard medical procedure. During colonoscopy, the lesions of colorectal tumors on the colon surface are visually inspected by a Narrow Band Imaging (NBI) zoom-videoendoscope. By using the visual appearance of colorectal tumors in endoscopic images, histological diagnosis is presumed based on classification schemes for NBI magnification findings. In this paper, we report on the performance of a recognition system for classifying NBI images of colorectal tumors into three types (A, B, and C3) based on the NBI magnification findings. To deal with the problem of computer-aided classification of NBI images, we explore a local feature-based recognition method, bag-of-visual-words (BoW), and provide extensive experiments on a variety of technical aspects. The proposed prototype system, used in the experiments, consists of a bag-of-visual-words representation of local features followed by Support Vector Machine (SVM) classifiers. A number of local features are extracted by using sampling schemes such as Difference-of-Gaussians and grid sampling. In addition, in this paper we propose a new combination of local features and sampling schemes. Extensive experiments with varying the parameters for each component are carried out, for the performance of the system is usually affected by those parameters, e.g. the sampling strategy for the local features, the representation of the local feature histograms, the kernel types of the SVM classifiers, the number of classes to be considered, etc. The recognition results are compared in terms of recognition rates, precision/recall, and F-measure for different numbers of visual words. The proposed system achieves a recognition rate of 96% for 10-fold cross validation on a real dataset of 908 NBI images collected during actual colonoscopy, and 93% for a separate test dataset.

  5. Uso tópico da adrenalina em diferentes concentrações na cirurgia endoscópica nasal Topical use of adrenaline in different concentrations for endoscopic sinus surgery

    Directory of Open Access Journals (Sweden)

    Krishnamurti Matos de Araujo Sarmento Junior

    2009-04-01

    Full Text Available A concentração ideal de adrenalina tópica a promover hemostasia adequada sem toxicidade ainda é motivo de controvérsia. OBJETIVO: Comparar soluções tópicas de adrenalina em diferentes concentrações. DESENHO DO ESTUDO: Prospectivo, duplo-cego, seleção aleatória. MATERIAIS E MÉTODOS: 49 pacientes submetidos à cirurgia endoscópica nasal, divididos em 3 grupos usando exclusivamente adrenalina tópica, nas concentrações de 1:2000, 1:10.000 e 1:50.000. Comparou-se o tempo operatório, o sangramento, as concentrações plasmáticas de adrenalina e noradrenalina e a variação dos parâmetros cardiovasculares. RESULTADOS: O tempo operatório por procedimento foi menor no grupo que utilizou adrenalina 1:2000, assim como o sangramento (p The ideal adrenaline concentration remains unknown. AIM: Compare topical adrenaline solutions in different concentrations. STUDY DESIGN: Prospective, double blind, randomized trial. PATIENTS AND METHODS: 49 patients divided in 3 groups underwent endoscopic sinus surgery, using only topical solutions of adrenaline in different concentrations (1:2,000, 1:10,000 and 1:50,000. We compared the duration of surgery, intra-operative bleeding, plasmatic levels of catecholamines, hemodynamic parameters and changes in heart rhythm. RESULTS: Surgery time was shorter in the group using adrenaline 1:2,000, which also showed less bleeding in all evaluations (objective and subjective - p < 0.0001. Plasmatic levels of epinephrine rose in all groups, more sharply in the 1:2,000 group. There was a trend towards elevation of blood pressure in the groups using adrenaline 1:2,000 and 1:10,000, with a greater occurrence of hypertensive peaks. DISCUSSION: We found a very significance bleeding difference favoring the 1:2,000. The blood pressure elevation in the 1:2,000 and 1:10,000 groups was progressive but very slow throughout the procedure, which could be associated with the anesthesia technique. CONCLUSION: We favor the use

  6. 鼻内窥镜在鼻腔鼻窦恶性肿瘤诊断和治疗中的价值%Value of endoscopic sinus surgery in the diagnosis and treatment of sinonasal malignancises

    Institute of Scientific and Technical Information of China (English)

    白伟良; 高鑫; 谭海燕; 曹志伟; 王振海

    2011-01-01

    目的 探讨鼻内窥镜手术诊断和治疗鼻腔鼻窦恶性肿瘤的价值.方法 鼻腔鼻窦恶性肿瘤43例,分别采取鼻内镜下肿瘤切除术、鼻内窥镜辅助下经上颌窦肿瘤切除术以及鼻内窥镜辅助下鼻侧切鼻腔鼻窦恶性肿瘤切除术等.结果 76.7%(33/43)的病例是在鼻内镜下直接取得病理,23.3%(10/43)病例是在鼻内镜辅助下柯陆氏入路进入上颌窦取得病理确诊.能够在鼻内窥镜下将鼻腔鼻窦肿瘤切除的占34.9%(15/43),在鼻内窥镜下取病理后进一步放疗或化疗的占20.9%(9/43),在鼻内窥镜辅助下经上颌窦将肿瘤切除的占11.6%(5/43),在鼻内窥镜辅助下经鼻侧将肿瘤切术的占20.9%(9/43),在鼻内窥镜下取病理后进一步上颌骨切除术的占11.6%(5/43).结论 鼻内窥镜手术对于明确鼻腔鼻窦恶性肿瘤的诊断,缓解症状、提高患者生存质量具有重要价值,并为其治疗提供了新的术式.%Objective To explore the value of endoscopic sinus surgery in the diagnosis and treatment of sinonasal malignancies.Methods Forty three cases of sinonasal malignancies were removed with the methods of endoscopy, Caldwell-Luc operation combined with endoscopy, nasal lateral approach combined with endoscopy and maxillary bone surgery,respectively.Results 76.7% (33/43) of the tumors were diagnosed under endoscopy, and 23.3% (10/43) of the other tumors were diagnosed through Caldwell-Luc route assisted by endoscopy.34.9% (15/43) of the tumors were removed completely under endoscopy.20.9 % (9/43) of the patients were treated with chemotherapy or radiotherapy after diagnosed under endoscopy.11.6% (5/43) of the tumors were removed with Caldwell-Luc operation combined with endoscopy.20.9% (9/43) of the tumors were removed through nasal lateral approach combined with endoscopy.11.6% (5/43) of the tumors needed to remove the partial or complete maxillary bone.Conclusion Endoscopic managenment of sinonasal malignancies is

  7. Computer-aided pulmonary image analysis in small animal models

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Ziyue; Mansoor, Awais; Mollura, Daniel J. [Center for Infectious Disease Imaging (CIDI), Radiology and Imaging Sciences, National Institutes of Health (NIH), Bethesda, Maryland 32892 (United States); Bagci, Ulas, E-mail: ulasbagci@gmail.com [Center for Research in Computer Vision (CRCV), University of Central Florida (UCF), Orlando, Florida 32816 (United States); Kramer-Marek, Gabriela [The Institute of Cancer Research, London SW7 3RP (United Kingdom); Luna, Brian [Microfluidic Laboratory Automation, University of California-Irvine, Irvine, California 92697-2715 (United States); Kubler, Andre [Department of Medicine, Imperial College London, London SW7 2AZ (United Kingdom); Dey, Bappaditya; Jain, Sanjay [Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States); Foster, Brent [Department of Biomedical Engineering, University of California-Davis, Davis, California 95817 (United States); Papadakis, Georgios Z. [Radiology and Imaging Sciences, National Institutes of Health (NIH), Bethesda, Maryland 32892 (United States); Camp, Jeremy V. [Department of Microbiology and Immunology, University of Louisville, Louisville, Kentucky 40202 (United States); Jonsson, Colleen B. [National Institute for Mathematical and Biological Synthesis, University of Tennessee, Knoxville, Tennessee 37996 (United States); Bishai, William R. [Howard Hughes Medical Institute, Chevy Chase, Maryland 20815 and Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States); Udupa, Jayaram K. [Medical Image Processing Group, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 (United States)

    2015-07-15

    Purpose: To develop an automated pulmonary image analysis framework for infectious lung diseases in small animal models. Methods: The authors describe a novel pathological lung and airway segmentation method for small animals. The proposed framework includes identification of abnormal imaging patterns pertaining to infectious lung diseases. First, the authors’ system estimates an expected lung volume by utilizing a regression function between total lung capacity and approximated rib cage volume. A significant difference between the expected lung volume and the initial lung segmentation indicates the presence of severe pathology, and invokes a machine learning based abnormal imaging pattern detection system next. The final stage of the proposed framework is the automatic extraction of airway tree for which new affinity relationships within the fuzzy connectedness image segmentation framework are proposed by combining Hessian and gray-scale morphological reconstruction filters. Results: 133 CT scans were collected from four different studies encompassing a wide spectrum of pulmonary abnormalities pertaining to two commonly used small animal models (ferret and rabbit). Sensitivity and specificity were greater than 90% for pathological lung segmentation (average dice similarity coefficient > 0.9). While qualitative visual assessments of airway tree extraction were performed by the participating expert radiologists, for quantitative evaluation the authors validated the proposed airway extraction method by using publicly available EXACT’09 data set. Conclusions: The authors developed a comprehensive computer-aided pulmonary image analysis framework for preclinical research applications. The proposed framework consists of automatic pathological lung segmentation and accurate airway tree extraction. The framework has high sensitivity and specificity; therefore, it can contribute advances in preclinical research in pulmonary diseases.

  8. Computer-Aided Construction of Chemical Kinetic Models

    Energy Technology Data Exchange (ETDEWEB)

    Green, William H. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2014-12-31

    The combustion chemistry of even simple fuels can be extremely complex, involving hundreds or thousands of kinetically significant species. The most reasonable way to deal with this complexity is to use a computer not only to numerically solve the kinetic model, but also to construct the kinetic model in the first place. Because these large models contain so many numerical parameters (e.g. rate coefficients, thermochemistry) one never has sufficient data to uniquely determine them all experimentally. Instead one must work in “predictive” mode, using theoretical rather than experimental values for many of the numbers in the model, and as appropriate refining the most sensitive numbers through experiments. Predictive chemical kinetics is exactly what is needed for computer-aided design of combustion systems based on proposed alternative fuels, particularly for early assessment of the value and viability of proposed new fuels before those fuels are commercially available. This project was aimed at making accurate predictive chemical kinetics practical; this is a challenging goal which requires a range of science advances. The project spanned a wide range from quantum chemical calculations on individual molecules and elementary-step reactions, through the development of improved rate/thermo calculation procedures, the creation of algorithms and software for constructing and solving kinetic simulations, the invention of methods for model-reduction while maintaining error control, and finally comparisons with experiment. Many of the parameters in the models were derived from quantum chemistry calculations, and the models were compared with experimental data measured in our lab or in collaboration with others.

  9. 鼻内镜术后中药鼻腔雾化吸入辅佐治疗慢性鼻-鼻窦炎的主客观评估%Subjective and objective assessment on chronic rhinosinusitis following adjuvant therapy of nasal inhalation withChinese medicine after endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    张弢; 张治军; 蒋梦穗; 袁波; 李春芳

    2011-01-01

    Objective To evaluate the efficacy of nasal inhalation with Chinese medicine in chronic rhinosinusitis (CRS) after endoscopic sinus surgery (ESS). Methods 63 cases of CRS were randomly divided into the treatment group (33 cases) and the control group (30 cases), and all had nasal inhalation following endoscopic sinus surgery (ESS). Bidouyan-oral was used for the treatment group, twice a day, at 8 mL, for five consecutive days, and then changed to once a week for 3 months. The control group used saline nasal inhalation, in the same way. Before inhalation, 5 days and 3 months later, the two groups were assessed in visual analogue scale, Lund-Kennedy score system and Lund-Mackay score system. Results On subjective symptoms, nasal endoscopy and sinus CT scan to check assessment, the difference between the treatment and control groups were significant. Before and after the spray the difference was also significant in each groups. Conclusion CRS patients after ESS for adjuvant use of traditional Chinese medicine treatment of inhalation, can significantly improve the surgical effect.%目的 评价慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)患者在鼻内镜术(endoscopic sinus surgery,ESS)后用中药进行鼻腔超声雾化吸入辅佐治疗的疗效.方法 63例CRS患者随机分为治疗组(33例)和对照组(30例),ESS术后第3天行鼻腔超声雾化吸入.治疗组雾化用药为鼻窦炎口服液,每天早晚各1次,每次8mL,连续5d,后改为每周1次,连续3个月.对照组使用生理盐水鼻腔雾化吸入,方法相同.雾化前(术后第2天)、雾化5 d和3个月后分别采用视觉模拟量表、Lund-Kennedy评分系统、Lund-Mackay评分法进行相关评估.结果 通过对主观症状、鼻内镜及鼻窦CT扫描进行检查评估,治疗组与对照组在雾化前后及组间比较差异均有统计学意义.结论 CRS患者ESS术后中药雾化吸入能明显提高手术疗效.

  10. [Orbital complications of sinusitis].

    Science.gov (United States)

    Šuchaň, M; Horňák, M; Kaliarik, L; Krempaská, S; Koštialová, T; Kovaľ, J

    2014-12-01

    Orbital complications categorised by Chandler are emergency. They need early diagnosis and agresive treatment. Stage and origin of orbital complications are identified by rhinoendoscopy, ophtalmologic examination and CT of orbite and paranasal sinuses. Periorbital cellulitis and early stage of orbital cellulitis can be treated conservatively with i. v. antibiotics. Monitoring of laboratory parameters and ophtalmologic symptoms is mandatory. Lack of improvement or worsening of symptoms within 24-48 hours and advanced stages of orbital complications are indicated for surgery. The purpose of the study is to evaluate epidemiology, clinical features and management of sinogenic orbital complications. Retrospective data of 8 patients with suspicion of orbital complication admited to hospital from 2008 to 2013 were evaluated. Patients were analyzed in terms of gender, age, CT findings, microbiology, clinical features, stage and treatment. Male and female were afected in rate 1,66:1. Most of patients were young adult in 3rd. and 4th. decade of life (62,5 %). Acute and chronic sinusitis were cause of orbital complication in the same rate. The most common origin of orbital complication was ethmoiditis (62,5 %), than maxillary (25 %) and frontal (12,5 %) sinusitis. Polysinusitis with affection of ethmoidal, maxillary and frontal sinuses (75 %) was usual CT finding. Staphylococcus epidermidis and Staphylococcus aureus were etiological agens in half of cases. Periorbital oedema (100 %), proptosis, chemosis (50 %), diplopia and glaucoma (12,5 %) were observed. Based on examinations, diagnosis of periorbital oedema/preseptal cellulitis was made in 3 (37,5 %), orbital cellulitis in 3 (37,5 %) and subperiosteal abscess in 2 cases (25 %). All patients underwent combined therapy - i. v. antibiotics and surgery within 24 hours. Eradication of disease from ostiomeatal complex (OMC), drainage of affected sinuses and drainage of subperiosteal abscess were done via fuctional endonasal

  11. 慢性鼻-鼻窦炎患者症状学特点及内镜鼻窦手术后主要症状的转归%Symptomatic characteristics of chronic rhinosinusitis patients and symptom-specific outcomes after endoscopic sinus surgery

    Institute of Scientific and Technical Information of China (English)

    万龙; 石农; 王园园; 刘争; 崔永华

    2009-01-01

    目的:探讨慢性鼻-鼻窦炎患者的症状学特点及内镜鼻窦手术前后患者主观症状的变化.方法:采用视觉模拟量表对119例慢性鼻-鼻窦炎患者(52例不伴鼻息肉和67例伴鼻息肉)的鼻塞、头昏(头痛)、面部疼痛(胀满感)、嗅觉障碍和鼻分泌物(后鼻漏)5个主要症状进行评分,比较内镜鼻窦手术前和手术后12个月评分的变化.结果:伴和不伴鼻息肉的慢性鼻-鼻窦炎患者出现最多的症状均依次为鼻塞、鼻分泌物(后鼻漏)、头昏(头痛)、面部疼痛(胀满感)和嗅觉障碍.不伴鼻息肉的慢性鼻-鼻窦炎患者较伴鼻息肉者鼻分泌物评分显著增高(P<0.01),但嗅觉障碍评分者显著降低(P<0.01).在最令人困扰的症状方面,不伴鼻息肉和伴鼻息肉的慢性鼻-鼻窦炎患者分别是鼻分泌物(后鼻漏)和嗅觉障碍.术后伴鼻息肉和不伴鼻息肉的慢性鼻-鼻窦炎患者各个症状出现的频率和评分均较术前显著降低(P<0.01).结论:伴鼻息肉和不伴鼻息肉的慢性鼻-鼻窦炎患者症状学具有不同的特点,内镜鼻窦手术可以显著改善患者的主观症状,视觉模拟量表评估患者的主观症状是一简便、易于开展的慢性鼻-鼻窦炎疗效主观评估方法.%Objective:To explore the symptomatic characteristics of chronic rhinosinusitis patients and the report symptom-based outcomes after endoscopic sinus surgery. Method: One hundred and nineteen chronic rhinosinusitis patients underwent endoscopic sinus surgery, including 52 patients of chronic rhinosinusitis without nasal polyps and 67 patients of chronic rhinosinusitis with nasal polyps, were enrolled. Patients were asked to evaluate their symptoms before surgery and 12 months after endoscopic sinus surgery using 10 cm visual analog scale measures. Result: The most commonly reported symptoms were nasal obstruction, nasal discharge, headache, facial pressure and altered sense of smell. Compared with patients of

  12. Different types of fungal sinusitis occurring concurrently: implications for therapy.

    Science.gov (United States)

    Rupa, V; Thomas, Meera

    2013-02-01

    The purpose of this study is to describe the clinical and histopathological features, management and outcome of a series of patients with simultaneous occurrence of invasive and non-invasive fungal sinusitis (mixed fungal sinusitis). The histopathological records of patients with fungal sinusitis seen over the last 6 years were reviewed. The clinical, histopathological, treatment and follow up details of all cases with mixed fungal sinusitis were noted. Six cases of mixed fungal sinusitis with concurrent occurrence of chronic granulomatous fungal sinusitis and allergic fungal sinusitis (AFS) were seen during the study period. Most (83.3 %) had bilateral disease. All patients had undergone prior endoscopic sinus surgery at least once within the previous 2 years. Histopathological features showed predominance of invasive disease in half the patients. Except for one patient who did not report for follow up, all patients with predominant chronic granulomatous fungal sinusitis received systemic antifungal therapy and inhaled steroids. Those with predominant features of AFS received oral and inhaled steroids. Five patients with mixed fungal sinusitis who had follow up ranging from 6 months to 5 years were disease free following treatment. Mixed fungal sinusitis should be recognized by the surgeon and pathologist as a separate category of fungal sinusitis whose treatment depends on accurate histological diagnosis. A good outcome may be expected with appropriate therapy.

  13. Sinusitis (acute)

    Science.gov (United States)

    2008-01-01

    Introduction Acute sinusitis is defined pathologically, by transient inflammation of the mucosal lining of the paranasal sinuses lasting less than 4 weeks. Clinically, it is characterised by nasal congestion, rhinorrhoea, facial pain, hyposmia, sneezing, and, if more severe, additional malaise and fever. It affects 1−5% of the adult population each year in Europe. Methods and outcomes We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments in people with clinically diagnosed acute sinusitis, and with radiologically or bacteriologically confirmed acute sinusitis? We searched: Medline, Embase, The Cochrane Library and other important databases up to August 2007 (BMJ Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). Results We found 19 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. Conclusions In this systematic review we present information relating to the effectiveness and safety of the following interventions: antibiotics (amoxicillin, co-amoxiclav, doxycycline, cephalosporins, macrolides, different doses [amoxicillin, co-amoxiclav, doxycycline, cephalosporins, macrolides], long-course regimens), antihistamines, cephalosporins or macrolides, decongestants (xylometazoline, phenylephrine, pseudoephedrine), doxycycline, saline nasal washes, steam inhalation, and topical corticosteroids (intra-nasal). PMID:19450327

  14. ENDOSCOPIC RESECTION OF GIANT ETHMOIDAL OSTEOMA WITH INTRAORBITAL EXTENSION

    Directory of Open Access Journals (Sweden)

    Somu

    2014-12-01

    Full Text Available : Osteomas are slow growing benign tumors of the paranasal sinuses. Most of them are asymptomatic and are discovered incidentally on radiographs. Sometimes they may grow to produce symptoms like cosmetic deformity, proptosis, epiphora and visual disturbances. A case of giant ethmoid osteoma with intra orbital extension in 30 year old female that was managed endoscopically is discussed. CONCLUSION: Endoscopic approach along with intra nasal drill is a safe and effective technique in management of osteoma of nose and paranasal sinus.

  15. Development of the computer-aided process planning (CAPP system for polymer injection molds manufacturing

    Directory of Open Access Journals (Sweden)

    J. Tepić

    2011-10-01

    Full Text Available Beginning of production and selling of polymer products largely depends on mold manufacturing. The costs of mold manufacturing have significant share in the final price of a product. The best way to improve and rationalize polymer injection molds production process is by doing mold design automation and manufacturing process planning automation. This paper reviews development of a dedicated process planning system for manufacturing of the mold for injection molding, which integrates computer-aided design (CAD, computer-aided process planning (CAPP and computer-aided manufacturing (CAM technologies.

  16. Computer aided decision support system for cervical cancer classification

    Science.gov (United States)

    Rahmadwati, Rahmadwati; Naghdy, Golshah; Ros, Montserrat; Todd, Catherine

    2012-10-01

    Conventional analysis of a cervical histology image, such a pap smear or a biopsy sample, is performed by an expert pathologist manually. This involves inspecting the sample for cellular level abnormalities and determining the spread of the abnormalities. Cancer is graded based on the spread of the abnormal cells. This is a tedious, subjective and time-consuming process with considerable variations in diagnosis between the experts. This paper presents a computer aided decision support system (CADSS) tool to help the pathologists in their examination of the cervical cancer biopsies. The main aim of the proposed CADSS system is to identify abnormalities and quantify cancer grading in a systematic and repeatable manner. The paper proposes three different methods which presents and compares the results using 475 images of cervical biopsies which include normal, three stages of pre cancer, and malignant cases. This paper will explore various components of an effective CADSS; image acquisition, pre-processing, segmentation, feature extraction, classification, grading and disease identification. Cervical histological images are captured using a digital microscope. The images are captured in sufficient resolution to retain enough information for effective classification. Histology images of cervical biopsies consist of three major sections; background, stroma and squamous epithelium. Most diagnostic information are contained within the epithelium region. This paper will present two levels of segmentations; global (macro) and local (micro). At the global level the squamous epithelium is separated from the background and stroma. At the local or cellular level, the nuclei and cytoplasm are segmented for further analysis. Image features that influence the pathologists' decision during the analysis and classification of a cervical biopsy are the nuclei's shape and spread; the ratio of the areas of nuclei and cytoplasm as well as the texture and spread of the abnormalities

  17. Improved mammographic interpretation of masses using computer-aided diagnosis

    Energy Technology Data Exchange (ETDEWEB)

    Leichter, I. [Dept. of Electro-Optics, Jerusalem College of Technology (Israel); Fields, S.; Novak, B. [Dept. of Radiology, Hadassah University Hospital, Mt. Scopus Jerusalem (Israel); Nirel, R. [Dept. of Statistics, Hebrew University of Jerusalem, Mt. Scopus, Jerusalem (Israel); Bamberger, P. [Dept. of Electronics, Jerusalem College of Technology, Jerusalem (Israel); Lederman, R. [Department of Radiology, Hadassah University Hospital, Ein Kerem, Jerusalem (Israel); Buchbinder, S. [Department of Radiology, Montefiore Medical Center, University Hospital for the Albert Einstein College of Medicine, Bronx, New York (United States)

    2000-02-01

    The aim of this study was to evaluate the effectiveness of computerized image enhancement, to investigate criteria for discriminating benign from malignant mammographic findings by computer-aided diagnosis (CAD), and to test the role of quantitative analysis in improving the accuracy of interpretation of mass lesions. Forty sequential mammographically detected mass lesions referred for biopsy were digitized at high resolution for computerized evaluation. A prototype CAD system which included image enhancement algorithms was used for a better visualization of the lesions. Quantitative features which characterize the spiculation were automatically extracted by the CAD system for a user-defined region of interest (ROI). Reference ranges for malignant and benign cases were acquired from data generated by 214 known retrospective cases. The extracted parameters together with the reference ranges were presented to the radiologist for the analysis of 40 prospective cases. A pattern recognition scheme based on discriminant analysis was trained on the 214 retrospective cases, and applied to the prospective cases. Accuracy of interpretation with and without the CAD system, as well as the performance of the pattern recognition scheme, were analyzed using receiver operating characteristics (ROC) curves. A significant difference (p < 0.005) was found between features extracted by the CAD system for benign and malignant cases. Specificity of the CAD-assisted diagnosis improved significantly (p < 0.02) from 14 % for the conventional assessment to 50 %, and the positive predictive value increased from 0.47 to 0.62 (p < 0.04). The area under the ROC curve (A{sub z}) increased significantly (p < 0.001) from 0.66 for the conventional assessment to 0.81 for the CAD-assisted analysis. The A{sub z} for the results of the pattern recognition scheme was higher (0.95). The results indicate that there is an improved accuracy of diagnosis with the use of the mammographic CAD system above that

  18. Computer Aided Design of Polygalacturonase II from Aspergillus niger

    Directory of Open Access Journals (Sweden)

    Ibrahim Ali Noorbatcha

    2011-12-01

    Full Text Available Pectin is a complex polysaccharide found in the cell walls of plants and consisting mainly of esterified D-galacturonic acid resides in α-(1-4 chain. In production of fruit juice, pectin contributes to fruit juice viscosity, thereby reducing the juice production and increasing the filtration time. Polygalacturonase improves the juice production process by rapid degradation of pectin. In this project we have designed a novel polygalacturonase enzyme using computer aided design approaches. The three dimension structure of polygalacturonase is first modeled on the basis of the known crystal structure. The active site in this enzyme is identified by manual and automated docking methods. Lamarckian genetic algorithm is used for automated docking and the active site is validated by comparing with existing experimental data. This is followed by in silico mutations of the enzymes and the automated docking process is repeated using the mutant enzymes. The strength of the binding of the ligands inside the active site is evaluated by computing the binding score using Potential Mean Force (PMF method. The in silico mutations R256Q and K258N are found to decrease the binding strength of the ligand at the active site, indicating lowering of enzyme activity, which is consistent with the experimental results. Hence in silico mutations can be used to design new polygalacturonase enzymes with improved enzyme activity.ABSTRAK: Pektin adalah polisakarida kompleks yang terdapat di dalam dinding sel tumbuhan dan sebahagian besarnya terdiri daripada asid D-galakturonik terester yang ditemui di dalam rantaian α-(1-4. Dalam penghasilan jus buah-buahan, pektin menyumbang dalam kepekatan jus buah-buahan, di mana ia mengurangkan penghasilan jus dan menambahkan masa penapisan. Poligalakturonase meningkatkan proses penghasilan jus dengan pemecahan pektin dengan cepat. Dalam projek ini, kami telah merangka satu enzim poligalakturonase baru dengan menggunakan pendekatan reka

  19. Predictable Restorative Work Flow for Computer-Aided Design/Computer-Aided Manufacture-Fabricated Ceramic Veneers Utilizing a Virtual Smile Design Principle.

    Science.gov (United States)

    Lin, W S; Zandinejad, A; Metz, M J; Harris, B T; Morton, D

    2015-01-01

    The purpose of this case report was to present the use of a contemporary digital photograph-assisted virtual smile design principle, an intraoral digital impression, and computer-aided design/computer-aided manufacture-fabricated lithium disilicate ceramic veneers to treat a patient with esthetic needs in the maxillary anterior region. By using the proposed digital restorative work flow, this case report demonstrated an effective communication pathway between the patient, clinician, and dental laboratory technician. Effective communication can help to achieve a more predictable and satisfactory esthetic outcome.

  20. Clinical Features and Treatments of Odontogenic Sinusitis

    Science.gov (United States)

    Lee, Sung Jin

    2010-01-01

    Purpose The aim of this study was to investigate how clinical features such as sex, age, etiologic factors, and presenting symptoms of odontogenic sinusitis are differentiated from other types of sinusitis. Also, this study was designed to find methods for reducing the incidence of odontogenic sinusitis. Materials and Methods A retrospective chart analysis was completed on twenty-seven patients with odontogenic sinusitis. They were all treated at Kangbuk Samsung Hospital between February 2006 and August 2008. The study protocol and informed consent forms were approved by the institutional review boards for human beings at Kangbuk Samsung Hospital. Results Ten patients (37.0%) had dental implant related complications and 8 (29.6%) had dental extraction related complications. Unilateral purulent nasal discharge was the most common symptom (66.7%). The therapeutic modality included transnasal endoscopic sinus surgery in 19 (70.4%) patients, and a Caldwell-Luc operation in two (7.4%) patients. Conclusion In our study, there was no significant difference in the incidence between genders. The average age of the patients was 42.9 years. The incidence was highest in the fourth decade. There were no significant differences between the symptoms of odontogenic sinusitis and that of other types of sinusitis. However, almost all of the patients with odontogenic sinusitis had unilateral symptoms. Iatrogenic causes, which include dental implants and dental extractions, were the most common etiologic factors related to the development of odontogenic sinusitis. Therefore, a preoperative consultation between a rhinologist and a dentist prior to the dental procedure should be able to reduce the incidence of odontogenic sinusitis. PMID:20879062

  1. Computer aided design of microcircuits. Citations from the NTIS data base

    Science.gov (United States)

    Reed, W. E.

    1980-09-01

    Government sponsored research covering the computer aided design, modeling, layout, and packaging of integrated and other microelectronic circuits are cited. Computer programs and the use of computer graphics are included.

  2. Computer aided taxonomy (CAT): Approach for understanding systematics of marine biota

    Digital Repository Service at National Institute of Oceanography (India)

    Chavan, V.S.; Kavlekar, D.P.; Chandramohan, D.

    Computer aided taconomy (CAT) is gaining importance day by day. In order to familiarise the taxonomy and its continuing usage an attempt has made to develop a module for knowing the systematics of organisms and to generate automatic numerical code...

  3. Computer-aided Framework for Design of Pure, Mixed and Blended Products

    DEFF Research Database (Denmark)

    2015-01-01

    This paper presents a framework for computer-aided design of pure, mixed and blended chemical based products. The framework is a systematic approach to convert a Computer-aided Molecular, Mixture and Blend Design (CAMbD) formulation, based on needs and target properties, into a mixed integer non-......-linear program (MINLP). TheMINLP is sequentially solved through a decomposed optimization approach to solve the possibly large MINLP in a smaller set of sub-problems. The framework application is highlighted through a solvent design case study.......This paper presents a framework for computer-aided design of pure, mixed and blended chemical based products. The framework is a systematic approach to convert a Computer-aided Molecular, Mixture and Blend Design (CAMbD) formulation, based on needs and target properties, into a mixed integer non...

  4. Computer-aided Framework for Design of Pure, Mixed and Blended Products

    DEFF Research Database (Denmark)

    Cignitti, Stefano; Zhang, Lei; Gani, Rafiqul

    2015-01-01

    Design of novel chemical products with process and application considerations is an emerging topic in thefield of chemical and biochemical engineering. Methods, such as Computer Aided Molecular Design(CAMD) [1] and Computer-aided Mixture and Blend Design (CAMbD) [2], provide the possibility of de...... a solvent design case study.......Design of novel chemical products with process and application considerations is an emerging topic in thefield of chemical and biochemical engineering. Methods, such as Computer Aided Molecular Design(CAMD) [1] and Computer-aided Mixture and Blend Design (CAMbD) [2], provide the possibility...... of designing such products. However, these product design problems can quickly become large and difficult, if not infeasible, to solve through mathematical optimization. In addition, considerations of process,application, special product attributes, economic feasibility, environmental and sustainability...

  5. A Possible Association of Staphylococcus Enterotoxin B-induced Asthma and Sinusitis

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In order to gain insight into a possible association between chronic sinusitis and asthma,85 patients with sinusitis and asthma underwent functional endoscopic sinus surgical treatment and serum antibodies and cytokines were measured. The results showed that 51 out of 85 patients with high serum anti-Staphylococcus enterotoxin B (SEB) antibody before treatment obtained satisfactory results for both sinusitis and asthma. The high level of Th2 cytokine IL-4 was down regulated tothe levels of normal controls after sinus surgery. Thirty-four out of 85 patients did not show high serum anti-SEB antibody before sinus surgery and did not show much improvement in their asthmatic symptoms although sinusitis symptoms were resolved by sinus surgery. It was concluded that bacterial superantigen SEB (in the sinuses) might play a crucial role in the pathogenesis of lower airway hypersensitivity.

  6. Progress of the Computer-Aided Engineering of Electric Drive Vehicle Batteries (CAEBAT) (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Pesaran, A. A.; Han, T.; Hartridge, S.; Shaffer, C.; Kim, G. H.; Pannala, S.

    2013-06-01

    This presentation, Progress of Computer-Aided Engineering of Electric Drive Vehicle Batteries (CAEBAT) is about simulation and computer-aided engineering (CAE) tools that are widely used to speed up the research and development cycle and reduce the number of build-and-break steps, particularly in the automotive industry. Realizing this, DOE?s Vehicle Technologies Program initiated the CAEBAT project in April 2010 to develop a suite of software tools for designing batteries.

  7. Computer-Aided Transformation of PDE Models: Languages, Representations, and a Calculus of Operations

    Science.gov (United States)

    2016-01-05

    Computer-aided transformation of PDE models: languages, representations, and a calculus of operations A domain-specific embedded language called...languages, representations, and a calculus of operations Report Title A domain-specific embedded language called ibvp was developed to model initial...Computer-aided transformation of PDE models: languages, representations, and a calculus of operations 1 Vision and background Physical and engineered systems

  8. Advanced Methods for the Computer-Aided Diagnosis of Lesions in Digital Mammograms

    Science.gov (United States)

    2000-07-01

    classification of mammographic mass lesions. Radiology 213: 200, 1999. " Nishikawa R, Giger ML, Yarusso L, Kupinski M, Baehr A, Venta L,: Computer-aided...detection of mass lesions in digital mammography using radial gradient index filtering. Radiology 213: 229, 1999. " Maloney M, Huo Z, Giger ML, Venta L...Nishikawa R, Huo Z, Jiang Y, Venta L, Doi K: Computer-aided diagnosis (CAD) in breast imaging. Radiology 213: 507, 1999. -Final Report DAMD 17-96-1-6058 19

  9. Computer-Aided Prototyping Systems (CAPS) within the software acquisition process: a case study

    OpenAIRE

    Ellis, Mary Kay

    1993-01-01

    Approved for public release; distribution is unlimited This thesis provides a case study which examines the benefits derived from the practice of computer-aided prototyping within the software acquisition process. An experimental prototyping systems currently in research is the Computer Aided Prototyping System (CAPS) managed under the Computer Science department of the Naval Postgraduate School, Monterey, California. This thesis determines the qualitative value which may be realized by ...

  10. Ocular Manifestations of Bilateral Ethmoidal Sinus Mucopyocele: Case Report

    Directory of Open Access Journals (Sweden)

    Özge Saraç

    2011-10-01

    Full Text Available Mucoceles of the paranasal sinuses are slowly growing, epithelium-lined cystic lesions with sterile content. When the mucocele content becomes infected with a bacterial super-infection, the lesion is defined as mucopyocele. Mucoceles or mucopyoceles are commonly located in the frontal and anterior ethmoidal sinuses and can manifest with ocular signs and symptoms, mostly proptosis. In this report, we demonstrate a case of bilateral ethmoidal mucopyocele in a 53-year-old female who presented with reduced vision, diplopia, and proptosis. Computed tomography (CT scanning of the paranasal sinuses revealed cystic lesions filling the maxillary sinuses and anterior ethmoidal cells bilaterally and causing erosion in the walls of the sinuses. After marsupialization of the mucopyoceles was performed by endoscopic sinus surgery, the symptoms of the patient recovered rapidly. (Turk J Ophthalmol 2011; 41: 354-6

  11. MULTIDETECTOR CT STUDY OF ANATOMICAL VARIANTS OF ETHMOID SINUS

    Institute of Scientific and Technical Information of China (English)

    李玉华; 薛建平; 朱铭

    2004-01-01

    Objective To evaluate the significance of multidetector CT 3D reconstruction technique in showing anatomy of ethmoid sinus, at the same time, anatomic variations of ethmoid sinus and its clinical significance were also discussed. Methods 250 cases of ethmoid sinuses were scanned transversally by multidetector scaner, coronal and sagittal views were reconstructed. Results Coronal and sagittal views were good enough to make diagnosis. 5 kinds of common ethmoid sinus variations were seen, including pneumatization of ethmoid bulla (56. 5% ) , Onodi air cell(26% ) , Hailer cell(6. 5% ) ,low ethmoid foveolas( 4. 3% )and over intromigratiny lamella papyracea (6. 5% ). Conclusion The coronal and other special views of ethmoid sinus are showed clearly by 3 D reconstruction which can provide detailed image informations for functional endoscopic sinus surgery.

  12. Acute fungal sinusitis in neutropenic patients of Namazi hospital/ Shiraz

    Directory of Open Access Journals (Sweden)

    Parisa Badiee

    2008-09-01

    Full Text Available Introduction: Fungal sinusitis is a well known disease in immunocompromised patients, but recently many reports have indicated an increased prevalence of fungal sinusitis in otherwise healthy individuals. The aim of this study was to assess the frequency of invasive fungal sinusitis (IFS in neutropenic patients and to determine outcome factors that may affect their survival. Methods: A total of 142 patients who were undergoing chemotherapy were followed by clinical and radiological features suggestive of fungal sinusitis. Patients with fever, headache, facial swelling and radiological finding underwent endoscopic sinus surgery. The biopsy materials were studied by mycological and histopathological methods. Results: Eleven from 142 patients were identified to have IFS. The ethiologic agents were Aspergillus flavus (5 cases, Alternaria sp. (3 cases, Aspergillus fumigatus (2 cases and mucor (1 case. Eight of 11 cases died. Conclusions: Invasive fungal sinusitis causes a high rate of mortality among immunocompromised patients. Therefore, early diagnosis with aggressive medical and surgical intervention is critical for survival.

  13. One case report:removal of foreign body in ethmoidal sinus-medial orbital wall through nose assisted by endoscope%内镜辅助下经鼻取出筛窦-眶内侧壁异物1例

    Institute of Scientific and Technical Information of China (English)

    杨泽垠; 杨晓红

    2013-01-01

    The patient was male,20 years old,and complained of pain,bleeding and decreased vision after the right eye was injured by nail for an hour.Physical examination:right exophthalmos,conjunctival edema,skin laceration at the lower eyelid of right eye,limitation of eye movement,asymmetric eyes and weak light-reflecting.X-ray showed:metallic foreign body shadow in the right orbit,0.5 cm × 0.4 cm approximately.Orbit and paranasal sinus CT showed:1 hematoma of the right eye and inside.2 high density foreign body embedded in the bone wall of the inside of right orbit and ethmoid.3 medial wall fracture of right eye orbit.4 bilateral maxillary sinus and right ethmoidal sinus effusion.5 slightly left side of nasal septum.The patient was initially diagnosed as foreign body in right ethmoidal sinus,skin laceration of right lower eyelid,retrobulbar hematoma.

  14. Combined middle meatus and expand prelacrimal recess-maxillary ainus approach for endoscopic maxillary sinus surgery%鼻内镜下中鼻道联合下鼻道扩大泪前隐窝入路切除上颌窦良性病变

    Institute of Scientific and Technical Information of China (English)

    陈莹华; 张红春; 葛平江; 韦廷佳; 罗小钢; 黄佩娟

    2012-01-01

    To study surgical techniques and clinical applications of the intranasal endoscopic combined approach in maxillary sinus benign lesions surgery. Method: A retrospective clinical analysis of 27 patients 'whose unilateral maxillary sinus benign lesions operated by the intranasal endoscopic middle meatus with inferior meatus tears recess approach surgical treatment was studied. Resalt: Benign lesions were confirmed by pathology in all patients before and after surgery as to rule out malignancy.- All patients had been followed up for 12 to 24 months. Twenty-seven cases resulted in normal luminal epithelium and inferior turbinate shape after surgery. Only one case of papilloma relapsed 2 months after operation. So far, the papilloma has not recurred after the second surgery. There were no epiphora in all cases. Conclusion: Endonasal endoscopic expand anterior tears recess approach have great and clear view. This approach made us accurately, mini-invade and completely remove the maxillary sinus benign lesions. It is a physiological and functional surgery and has great advantage in the nasal cavity disease treatment.%目的:探讨鼻内镜下联合入路上颌窦良性病变的手术方法和临床价值.方法:回顾性分析经鼻内镜下中鼻道联合下鼻道泪前隐窝入路手术治疗27例单侧上颌窦良性病变患者临床资料,观察临床效果.结果:所有患者术中或术后均经病理证实为良性病变,排除恶性肿瘤.随访12~24个月,所有患者术腔上皮化,下鼻甲形态良好,均无溢泪发生.仅1例乳头状瘸术后2个月复发,局部处理后随访至今未见复发.结论:经鼻内镜下鼻道扩大泪前隐窝入路治疗上颌窦良性病变创伤小,手术视野广阔清晰,能够准确完整地清除病变,术腔符合鼻腔的生理结构和功能需要,具有很高的临床实用价值.

  15. Endoscopic ultrasound

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/007646.htm Endoscopic ultrasound To use the sharing features on this page, please enable JavaScript. Endoscopic ultrasound is a type of imaging test. It is ...

  16. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... equipment to evaluate the paranasal sinus cavities – hollow, air-filled spaces within the bones of the face ... paranasal sinus cavities. The paranasal sinuses are hollow, air-filled spaces located within the bones of the ...

  17. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... the Sinuses? What is CT (Computed Tomography) of the Sinuses? Computed tomography, more commonly known as a ... of page What are some common uses of the procedure? CT of the sinuses is primarily used ...

  18. Chronic sinusitis (image)

    Science.gov (United States)

    ... and cartilage and lined with a mucous membrane. Sinusitis occurs when the membranes becomes inflamed and painful, ... a result of a blocked sinus opening. Chronic sinusitis is often caused by inflammation and blockage due ...

  19. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... diagnose sinusitis . evaluate sinuses that are filled with fluid or thickened sinus membranes . detect the presence of ... conditions and whether you have a history of heart disease, asthma, diabetes, kidney disease or thyroid problems. ...

  20. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... the Sinuses? What is CT (Computed Tomography) of the Sinuses? Computed tomography, more commonly known as a ... of page What are some common uses of the procedure? CT of the sinuses is primarily used ...

  1. Computer-aided design of bromelain and papain covalent immobilization

    Directory of Open Access Journals (Sweden)

    Bessy Cutiño-Avila

    2014-06-01

    Full Text Available Título en español: Diseño asistido por computadora de la inmovilización covalente de bromelina y papaína.Título corto: Computer-aided design of bromelain and papain. Abstract: Enzymes as immobilized derivatives have been widely used in Food, Agrochemical, Pharmaceutical and Biotechnological industries. Protein immobilization is probably the most used technology to improve the operational stability of these molecules. Bromelain (Ananas comosus and papain (Carica papaya are cystein proteases extensively used as immobilized biocatalyst with several applications in therapeutics, racemic mixtures resolution, affinity chromatography and others industrial scenarios. The aim of this work was to optimize the covalent immobilization of bromelain and papain via rational design of immobilized derivatives strategy (RDID and RDID1.0 program. It was determined the maximum protein quantity to immobilize, the optimum immobilization pH (in terms of functional activity retention, and the most probable configuration of the immobilized derivative and the probabilities of multipoint covalent attachment was also predicted. As support material Glyoxyl-Sepharose CL 4B was used.  The accuracy of RDID1.0 program´s prediction was demonstrated comparing with experimental results. Bromelain and papain immobilized derivatives showed desired characteristics for industrial biocatalysis, such as: elevate pH stability retaining 95% and 100% residual activity at pH 7.0 and 8.0, for bromelain and papain, respectively; high thermal stability at 30 °C retaining 90% residual activity for both immobilized enzymes; a catalytic configuration bonded by immobilization at optimal pH; and the ligand load achieved, ensures the minimization of diffusional restrictions.Key words: bromelain, covalent immobilization, immobilized derivatives, papain, rational design.Resumen: Las enzimas inmovilizadas han sido ampliamente utilizadas en las industrias Alimentaria, Agroquímica, Farmac

  2. [The role of carbocystein in the treatment of sinusitis].

    Science.gov (United States)

    Dąbrowski, Piotr; Leszczyńska, Małgorzata; Mielcarek-Kuchta, Daniela

    2012-09-01

    Chronic sinusitis is one of the most common presenting complaints of all doctor visits in the United States and Europe, with more than 13% of people affected in any given year. This disease has a wide range of impact on communities. Patients with recurrent or chronic sinusitis report a deteriorative sense of general health and vitality, when compared to general population. In our Department we perform about 600 functional endoscopic sinus surgeries (FESS) per year. Chronic rhinosinusitis represents a spectrum of inflammatory and infectious processes concurrently affecting the nose and paranasal sinuses. Among chronic paranasal sinusitis one must single out paranasal sinusitis with and without polyps. In the paranasal sinusitis patomechanism the blockage of natural ostium plays one of the most important roles. The closure of sinus proper ventilation passages leads to the triggering of many pathological occurrences within mucous membrane of this region. The treatment of paranasal sinusitis is diversified and involves a surgical procedure as well as anti-inflammatory and antiallergic drugs (medications) and mucolytics. Its purpose is to clear the nose through the elimination of bacterial infection, liquidating and removal of lying discharge and the restoration of the proper muco-ciliary transportation, and through this the improvement of local condition and faster recovery. In this work the usage of carboxycysteine to treat paranasal sinus conditions has been presented. Copyright © 2012 Polish Otolaryngology Society. Published by Elsevier Urban & Partner Sp. z.o.o. All rights reserved.

  3. Plain Language Summary: Adult Sinusitis (Sinus Infection).

    Science.gov (United States)

    Caspersen, Leslie A; Walter, Lindsey M; Walsh, Sandra A; Rosenfeld, Richard M; Piccirillo, Jay F

    2015-08-01

    This plain language summary serves as an overview in explaining sinusitis (pronounced sign-you-side-tis). The purpose of this plain language summary is to provide patients with standard language explaining their condition in an easy-to-read format. This summary applies to those 18 years of age or older with sinusitis. The summary is featured as an FAQ (frequently asked question) format. The summary addresses how to manage and treat sinusitis symptoms. Adult sinusitis is often called a sinus infection. A healthcare provider may refer to a sinus infection as rhinosinusitis (pronounced rhi-no-sign-you-side-tis). This includes the nose as well as the sinuses in the name. A sinus infection is the swelling of the sinuses and nasal cavity.The summary is based on the published 2015 "Clinical Practice Guideline: Adult Sinusitis." The evidence-based guideline includes research to support more effective diagnosis and treatment of adult sinus infections. The guideline was developed as a quality improvement opportunity for managing sinus infections by creating clear recommendations to use in medical practice. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2015.

  4. [Atelectasis of the maxillary sinus. Analysis of progression stages. Apropos of 4 cases].

    Science.gov (United States)

    Hazan, A; Le Roy, A; Chevalier, E; Benzaken, J; Waisberg, A; Cymbalista, M; Adotti, F; Peytral, C

    1998-12-01

    We analyzed atelectasic processes occurring in the maxillary sinus. Several publications in the literature have tempted to analyze the pathogenesis. Clinically the processes are often silent and only revealed when the major opthalmological complication, enophthalmia, becomes patent. In other cases there is a long history of chronic sinusitis. There is a spectacular retraction of the maxillary sinus walls leading to collapse of the orbital floor and enophthalmia. We report four cases of maxillary sinusitis with atelectasia of the sinus walls at different stages of progression. These observations and data in the literature emphasize the importance, whatever the state of development, of endoscopic osteal decompression to avoid ophthalmological complications.

  5. Trichosporon inkin, an unusual agent of fungal sinusitis: A report from south India

    Directory of Open Access Journals (Sweden)

    Anand Janagond

    2012-01-01

    Full Text Available The aetiology of fungal sinusitis is diverse and changing. Aspergillus species has been the most common cause for fungal sinusitis, especially in dry and hot regions like India. Trichosporon species as a cause for fungal sinusitis has been very rarely reported the world over. Here, we report a rare case of allergic fungal sinusitis caused by Trichosporon inkin in a 28-year-old immunocompetent woman. Bilateral nasal obstruction, nasal discharge and loss of smell were her presenting complaints. Diagnostic nasal endoscopy showed bilateral multiple polyps. Functional endoscopic sinus surgery was performed and many polyps were removed. Based on mycological and histopathological studies, the pathogen was identified as T. inkin.

  6. Trichosporon inkin, an unusual agent of fungal sinusitis: a report from south India.

    Science.gov (United States)

    Janagond, Anand; Krishnan, K Mohana; Kindo, A J; Sumathi, G

    2012-01-01

    The aetiology of fungal sinusitis is diverse and changing. Aspergillus species has been the most common cause for fungal sinusitis, especially in dry and hot regions like India. Trichosporon species as a cause for fungal sinusitis has been very rarely reported the world over. Here, we report a rare case of allergic fungal sinusitis caused by Trichosporon inkin in a 28-year-old immunocompetent woman. Bilateral nasal obstruction, nasal discharge and loss of smell were her presenting complaints. Diagnostic nasal endoscopy showed bilateral multiple polyps. Functional endoscopic sinus surgery was performed and many polyps were removed. Based on mycological and histopathological studies, the pathogen was identified as T. inkin.

  7. Sinusitis (For Parents)

    Science.gov (United States)

    ... Teaching Kids to Be Smart About Social Media Sinusitis KidsHealth > For Parents > Sinusitis Print A A A What's in this article? Causes Symptoms Prevention Treatment en español Sinusitis Sinuses are moist air spaces within the bones ...

  8. Pilot decision making in a computer-aided flight management situation

    Science.gov (United States)

    Chu, Y. Y.; Rouse, W. B.

    1978-01-01

    An experimental representation of a computer-aided multi-task flight management situation has been developed. A computer aiding program was implemented to serve as a back-up decision maker. An experiment was conducted with a balanced design of several subject runs for different workload levels. This was achieved using three levels of subsystem event arrival rates, three levels of control task involvement, and three levels of availability of computer aiding. Experimental results compared quite favorably with those from a computer simulation which employed a queueing model. It was shown that the aiding had enhanced system performance as well as subjective ratings, and that the adaptive aiding policy further reduced subsystem delay.

  9. The application of computer-aided designated titanium mesh in repairing skull defects

    Directory of Open Access Journals (Sweden)

    Lei ZHANG

    2015-01-01

    Full Text Available Objective To explore the clinical value of repairing skull defects with titanium alloy-mesh of computer-aided design.  Methods A retrospective analysis was done on clinical data of 86 cases with skull defects who underwent repairing using titanium mesh with two-dimensional or three-dimensional computer-aided design.  Results All the incisions achieved primary healing other than one case conducting reoperation due to exposed titanium mesh. Two cases got subcutaneous exudate, one obtained painful mastication and one experienced proliferation of scalp scar.  Conclusions With the computer-aided designated titanium mesh, relevant operation can resume the original state to maximum extent, lower surgical risk, decrease post-operational complications and then obtain satisfying clinical effect. DOI: 10.3969/j.issn.1672-6731.2015.01.015

  10. The Research of Computer Aided Farm Machinery Designing Method Based on Ergonomics

    Science.gov (United States)

    Gao, Xiyin; Li, Xinling; Song, Qiang; Zheng, Ying

    Along with agricultural economy development, the farm machinery product type Increases gradually, the ergonomics question is also getting more and more prominent. The widespread application of computer aided machinery design makes it possible that farm machinery design is intuitive, flexible and convenient. At present, because the developed computer aided ergonomics software has not suitable human body database, which is needed in view of farm machinery design in China, the farm machinery design have deviation in ergonomics analysis. This article puts forward that using the open database interface procedure in CATIA to establish human body database which aims at the farm machinery design, and reading the human body data to ergonomics module of CATIA can product practical application virtual body, using human posture analysis and human activity analysis module to analysis the ergonomics in farm machinery, thus computer aided farm machinery designing method based on engineering can be realized.

  11. A Multi-step and Multi-level approach for Computer Aided Molecular Design

    DEFF Research Database (Denmark)

    A general multi-step approach for setting up, solving and solution analysis of computer aided molecular design (CAMD) problems is presented. The approach differs from previous work within the field of CAMD since it also addresses the need for a computer aided problem formulation and result analysis....... The problem formulation step incorporates a knowledge base for the identification and setup of the design criteria. Candidate compounds are identified using a multi-level generate and test CAMD solution algorithm capable of designing molecules having a high level of molecular detail. A post solution step...... using an Integrated Computer Aided System (ICAS) for result analysis and verification is included in the methodology. Keywords: CAMD, separation processes, knowledge base, molecular design, solvent selection, substitution, group contribution, property prediction, ICAS Introduction The use of Computer...

  12. Study on computer-aided alignment method of reflective zoom systems

    Science.gov (United States)

    Zhou, Jide; Chang, Jun; Xie, Guijuan; Zhang, Ke

    2015-08-01

    Computer-aided alignment is an effective method to improve the imaging quality of high-precision, complex, and off-axis optical systems. However, how to determine the misalignment quickly, exactly and constantly is essential to the technology of computer-aided alignment. Owing to the varying optical characteristics of a zoom system, sensitivity matrices are used in the alignment rather than a single matrix. Thus, the processing of sensitivity matrices is important for the computer-aided alignment of the reflective zoom system. So, the total least squares is proposed in order to solve the problems of the numerical instability and the result inaccuracy which result from the solution of the least squares method directly. Finally, the simulant calculation is processed using the numerical analysis model established in the essay. The results demonstrate that the computation method is rational and effective.

  13. Research on the Procedure for Computer-Aided Pattern Design of Uygur's Flowered Hats

    Directory of Open Access Journals (Sweden)

    Shuxian Liu

    2013-05-01

    Full Text Available Xinjiang Uygur’s flowered hats is famous all over the world, it leads the world of headwear of variou nationalities within China by the variety of styles, the various ways of how to emroider pattern design and exquisite manufacture. It is unusual even in national costumes art of the world. The poupose of this study is to analyze Uygur's headwear, study the rules of Uygur's headwear pattern, analyze the characteristic of the basic pattern, research on the procedure for computer-aided pattern design of Uygur's flowered hat, explore the application of computer-aided design in traditional costume's pattern design and to realize application exploration of computer-aided design in designing of costume and dress adornment.

  14. Computer-aided modeling framework for efficient model development, analysis and identification

    DEFF Research Database (Denmark)

    Heitzig, Martina; Sin, Gürkan; Sales Cruz, Mauricio;

    2011-01-01

    branches; the first branch deals with single-scale model development while the second branch introduces features for multiscale model development to the methodology. In this paper, the emphasis is on single-scale model development and application part. The modeling framework and the supported stepwise......Model-based computer aided product-process engineering has attained increased importance in a number of industries, including pharmaceuticals, petrochemicals, fine chemicals, polymers, biotechnology, food, energy, and water. This trend is set to continue due to the substantial benefits computer......-aided methods introduce. The key prerequisite of computer-aided product-process engineering is however the availability of models of different types, forms, and application modes. The development of the models required for the systems under investigation tends to be a challenging and time-consuming task...

  15. [An anatomical study of maxillary sinus septum of Han population in Jiangsu region using cone-beam CT].

    Science.gov (United States)

    Li, Jun; Zhou, Zhi-xuan; Yuan, Zhi-yao; Yuan, Hua; Sun, Chao; Chen, Ning

    2013-02-01

    To examine the anatomical variation of maxillary sinus septum of Han nationality in Jiangsu region by using cone-beam computed tomography (CBCT) combined with Simplant software in order to provide anatomical basis and operation instruction for oral implants after maxillary sinus lifting. CBCT image data were collected from 424 patients for analysis of maxillary sinus septa. Digital imaging and communications in medicine (Dicom) image files were fed into the computer-aided Simplant software and used to analyze the prevalence, location, height, orientation, and morphology of maxillary sinus septa through three-dimensional reconstruction. The data was analyzed with SPSS17.0 software package. The proportion of the occurrence of maxillary sinus septa in 424 subjects was 44.81% and 21.23% of the subjects (n=90) had multiple sinus septa, while 20.52% had bilateral sinus septa (n=87). Totally 848 maxillary sinuses were observed in this study and 277 sinuses had septa with a proportion of 32.67%. The prevalence of septa was not significantly related to gender, age, and the presence or absence of teeth. Septa were located most frequently in the middle of maxillary sinus (59.94%). The mean height of sinus septa was (5.90±3.65) mm and (5.54±2.87) mm in the right and left maxillary sinus, respectively. The mean length of sinus septa was (8.15±2.40) mm and (7.88±2.73) mm in the right and left maxillary sinus, respectively. Nearly 44.81% of Han population in Jiangsu region have maxillary sinus septa. The CBCT imaging technique can provide comprehensive and accurate quantitative analysis of maxillary sinus septa and is meaningful to provide anatomical basis and clinical guidance before sinus augmentation procedures.

  16. Energy-aware memory management for embedded multimedia systems a computer-aided design approach

    CERN Document Server

    Balasa, Florin

    2011-01-01

    Energy-Aware Memory Management for Embedded Multimedia Systems: A Computer-Aided Design Approach presents recent computer-aided design (CAD) ideas that address memory management tasks, particularly the optimization of energy consumption in the memory subsystem. It explains how to efficiently implement CAD solutions, including theoretical methods and novel algorithms. The book covers various energy-aware design techniques, including data-dependence analysis techniques, memory size estimation methods, extensions of mapping approaches, and memory banking approaches. It shows how these techniques

  17. Computer-Aided Model Based Analysis for Design and Operation of a Copolymerization Process

    DEFF Research Database (Denmark)

    Lopez-Arenas, Maria Teresa; Sales-Cruz, Alfonso Mauricio; Gani, Rafiqul

    2006-01-01

    The advances in computer science and computational algorithms for process modelling, process simulation, numerical methods and design/synthesis algorithms, makes it advantageous and helpful to employ computer-aided modelling systems and tools for integrated process analysis. This is illustrated....... This will allow analysis of the process behaviour, contribute to a better understanding of the polymerization process, help to avoid unsafe conditions of operation, and to develop operational and optimizing control strategies. In this work, through a computer-aided modeling system ICAS-MoT, two first......, the process design and conditions of operation on the polymer grade and the production rate....

  18. Management of fungal sinusitis: A retrospective study in a medical college hospital

    Directory of Open Access Journals (Sweden)

    Sudhir M Naik

    2015-07-01

    Full Text Available Background/ objectives: Fungus balls are extra-mucosal collections of fungal elements, usually localized to a single sinus cavity, commonly the maxillary sinus. They appear as partial or complete heterogeneous opacification of the involved sinus with occasional metal dense opacities on CT scan. Here we report a case series of fungal sinusitis with multiple sinus involvement. Materials and methods: We report a case series analysis of 46 cases of fungal sinusitis managed in our department for the past 3 years. Mean age in our study group was 32.45 years, with 15 males(mean age – 35.46 yrs and 31 females ( mean age –31 yrs. All were operated with endoscopic sinus surgery after CT findings positive of fungal sinusitis. Result: Fungal ball was seen in 36 (78.26% cases and invasive fungal sinusitis were seen in 8 (17.39%cases. 4 cases did not yield any growth and only secondary bacterial infection were seen on bacterial culture. 34 cases had disease in the maxillary sinus. 9 cases had bilateral growth and the rest unilateral only. 16 cases had disease in the sphenoid while 6 cases had both maxillary and sphenoid disease. 2 cases had ethmoidal disease. Conclusion: Endoscopic sinus surgery is treatment of choice for non-invasive fungus ball. Local or systemic antifungal therapy are reserved for extensive and invasive fungal diseases.

  19. Balloon catheter dilation technology combined with a fibrolaryngoscope to treat a maxillary sinus cyst.

    Science.gov (United States)

    Xiao, Jianxin; Chen, Junming; Wang, Yuejian

    2016-02-01

    A prospective randomized controlled study was conducted to investigate the effect of balloon catheter dilation technology combined with a fibrolaryngoscope in the treatment of a maxillary sinus cyst. The clinical data of 14 cases (19 maxillary sinuses) with balloon catheter dilation technology combined with a fibrolaryngoscope to remove sinus cysts (balloon group) and 16 cases (23 maxillary sinuses) with conventional nasal endoscopic sinus surgery to remove sinus cysts (conventional group) were analyzed. All cases have completed the preoperative and postoperative SNOT-20, nasal endoscopy and coronal sinus CT scan. Lund-Kennedy endoscopic and Lund-Mackay CT scan staging scores were recorded. All patients were followed up for 24 weeks after the operation. The SNOT-20 scores, Lund-Kennedy endoscopic and Lund-Mackay CT scan staging scores were lower in the balloon group than that in the control group. Balloon catheter dilation technology combined with a fibrolaryngoscope can effectively preserve the function and structures of the nasal cavity and sinus, making it a good choice in the treatment of a retention cyst of the maxillary sinus.

  20. Computer-Aided psychotherapy for anxiety disorders: A meta-analytic review

    NARCIS (Netherlands)

    Cuijpers, P.; Marks, I.M.; Straten, van A.; Cavanagh, K; Gega, L.; Andersson, G.

    2009-01-01

    Computer-aided psychotherapy (CP) is said to (1) be as effective as face-to-face psychotherapy, while requiring less therapist time, for anxiety disorder sufferers, (2) speed access to care, and (3) save traveling time. CP may be delivered on stand-alone or Internet-linked computers, palmtop compute

  1. CONTRIBUTIONS FOR DEVELOPING OF A COMPUTER AIDED LEARNING ENVIRONMENT OF DESCRIPTIVE GEOMETRY

    Directory of Open Access Journals (Sweden)

    Antonescu Ion

    2009-07-01

    Full Text Available The paper presents the authors’ contributions for developing a computer code for teaching of descriptive geometry using the computer aided learning techniques. The program was implemented using the programming interface and the 3D modeling capabilities of the AutoCAD system.

  2. On Combining Multiple-Instance Learning and Active Learning for Computer-Aided Detection of Tuberculosis

    NARCIS (Netherlands)

    Melendez Rodriguez, J.C.; Ginneken, B. van; Maduskar, P.; Philipsen, R.H.H.M.; Ayles, H.; Sanchez, C.I.

    2016-01-01

    The major advantage of multiple-instance learning (MIL) applied to a computer-aided detection (CAD) system is that it allows optimizing the latter with case-level labels instead of accurate lesion outlines as traditionally required for a supervised approach. As shown in previous work, a MIL-based

  3. Computer-Aided Detection of Polyps in CT Colonography Using Logistic Regression

    NARCIS (Netherlands)

    Van Ravesteijn, V.F.; Van Wijk, C.; Vos, F.M.; Truyen, R.; Peters, J.F.; Stoker, J.; Van Vliet, L.J.

    2010-01-01

    We present a computer-aided detection (CAD) system for computed tomography colonography that orders the polyps according to clinical relevance. TheCADsystem consists of two steps: candidate detection and supervised classification. The characteristics of the detection step lead to specific choices fo

  4. Integrated Computer Aided Planning and Manufacture of Advanced Technology Jet Engines

    Directory of Open Access Journals (Sweden)

    B. K. Subhas

    1987-10-01

    Full Text Available This paper highlights an attempt at evolving a computer aided manufacturing system on a personal computer. A case study of an advanced technology jet engine component is included to illustrate various outputs from the system. The proposed system could be an alternate solution to sophisticated and expensive CAD/CAM workstations.

  5. Computer Aided Phenomenography: The Role of Leximancer Computer Software in Phenomenographic Investigation

    Science.gov (United States)

    Penn-Edwards, Sorrel

    2010-01-01

    The qualitative research methodology of phenomenography has traditionally required a manual sorting and analysis of interview data. In this paper I explore a potential means of streamlining this procedure by considering a computer aided process not previously reported upon. Two methods of lexicological analysis, manual and automatic, were examined…

  6. The computer-aided design of a servo system as a multiple-criteria decision problem

    NARCIS (Netherlands)

    Udink ten Cate, A.J.

    1986-01-01

    This paper treats the selection of controller gains of a servo system as a multiple-criteria decision problem. In contrast to the usual optimization-based approaches to computer-aided design, inequality constraints are included in the problem as unconstrained objectives. This considerably simplifies

  7. Application of computer-aided multi-scale modelling framework - Aerosol case study

    DEFF Research Database (Denmark)

    Heitzig, Martina; Gregson, Christopher; Sin, Gürkan;

    2011-01-01

    A computer-aided modelling tool for efficient multi-scale modelling has been developed and is applied to solve a multi-scale modelling problem related to design and evaluation of fragrance aerosol products. The developed modelling scenario spans three length scales and describes how droplets...

  8. SMART USE OF COMPUTER-AIDED SPERM ANALYSIS (CASA) TO CHARACTERIZE SPERM MOTION

    Science.gov (United States)

    Computer-aided sperm analysis (CASA) has evolved over the past fifteen years to provide an objective, practical means of measuring and characterizing the velocity and parttern of sperm motion. CASA instruments use video frame-grabber boards to capture multiple images of spermato...

  9. Using the Web To Improve Computer-Aided Instruction in Economics.

    Science.gov (United States)

    Daniel, Joseph I.

    1999-01-01

    Believes that the World Wide Web has great potential for delivering interactive computer-aided instruction using programming language like Java and Javascript. Describes a website on object-oriented microeconomics that integrates a textbook, mini-lecture series, graphical calculator, animated drawing program, spreadsheet, and regression package.…

  10. Lecturers' Perspectives on the Use of a Mathematics-Based Computer-Aided Assessment System

    Science.gov (United States)

    Broughton, Stephen J.; Robinson, Carol L.; Hernandez-Martinez, Paul

    2013-01-01

    Computer-aided assessment (CAA) has been used at a university with one of the largest mathematics and engineering undergraduate cohorts in the UK for more than ten years. Lecturers teaching mathematics to first year students were asked about their current use of CAA in a questionnaire and in interviews. This article presents the issues that these…

  11. Persons with Alzheimer's Disease Make Phone Calls Independently Using a Computer-Aided Telephone System

    Science.gov (United States)

    Perilli, Viviana; Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Cassano, Germana; Cordiano, Noemi; Pinto, Katia; Minervini, Mauro G.; Oliva, Doretta

    2012-01-01

    This study assessed whether four patients with a diagnosis of Alzheimer's disease could make independent phone calls via a computer-aided telephone system. The study was carried out according to a non-concurrent multiple baseline design across participants. All participants started with baseline during which the telephone system was not available,…

  12. Automatic computer-aided detection of prostate cancer based on multiparametric magnetic resonance image analysis.

    NARCIS (Netherlands)

    Vos, P.C.; Barentsz, J.O.; Karssemeijer, N.; Huisman, H.J.

    2012-01-01

    In this paper, a fully automatic computer-aided detection (CAD) method is proposed for the detection of prostate cancer. The CAD method consists of multiple sequential steps in order to detect locations that are suspicious for prostate cancer. In the initial stage, a voxel classification is performe

  13. Virtual Reality versus Computer-Aided Exposure Treatments for Fear of Flying

    Science.gov (United States)

    Tortella-Feliu, Miquel; Botella, Cristina; Llabres, Jordi; Breton-Lopez, Juana Maria; del Amo, Antonio Riera; Banos, Rosa M.; Gelabert, Joan M.

    2011-01-01

    Evidence is growing that two modalities of computer-based exposure therapies--virtual reality and computer-aided psychotherapy--are effective in treating anxiety disorders, including fear of flying. However, they have not yet been directly compared. The aim of this study was to analyze the efficacy of three computer-based exposure treatments for…

  14. Computer-aided detection in breast MRI : a systematic review and meta-analysis

    NARCIS (Netherlands)

    Dorrius, Monique D.; Jansen-van der Weide, Marijke C.; van Ooijen, Peter M. A.; Pijnappel, Ruud M.; Oudkerk, Matthijs

    To evaluate the additional value of computer-aided detection (CAD) in breast MRI by assessing radiologists' accuracy in discriminating benign from malignant breast lesions. A literature search was performed with inclusion of relevant studies using a commercially available CAD system with automatic

  15. Standalone computer-aided detection compared to radiologists' performance for the detection of mammographic masses

    NARCIS (Netherlands)

    Hupse, R.; Samulski, M.; Lobbes, M.; Heeten, A. den; Imhof-Tas, M.W.; Beijerinck, D.; Pijnappel, R.; Hitge-Boetes, C.; Karssemeijer, N.

    2013-01-01

    OBJECTIVES: We developed a computer-aided detection (CAD) system aimed at decision support for detection of malignant masses and architectural distortions in mammograms. The effect of this system on radiologists' performance depends strongly on its standalone performance. The purpose of this study

  16. Gathering Empirical Evidence Concerning Links between Computer Aided Design (CAD) and Creativity

    Science.gov (United States)

    Musta'amal, Aede Hatib; Norman, Eddie; Hodgson, Tony

    2009-01-01

    Discussion is often reported concerning potential links between computer-aided designing and creativity, but there is a lack of systematic enquiry to gather empirical evidence concerning such links. This paper reports an indication of findings from other research studies carried out in contexts beyond general education that have sought evidence…

  17. Computer aided design of prosthetic sockets for below-knee amputees.

    Science.gov (United States)

    Saunders, C G; Foort, J; Bannon, M; Lean, D; Panych, L

    1985-04-01

    A computer-aided sculpting system for use in prosthetics is described. The prosthetist's sculpting tools now consist of a computer, a graphics terminal, a mouse and an on-screen moveable cursor. Accompanied by the system software, these tools allow systematic modification of a primitive socket using techniques analogous to those used by a prosthetist working with rasps and plaster.

  18. Shape sensing for computer aided below-knee prosthetic socket design.

    Science.gov (United States)

    Fernie, G R; Griggs, G; Bartlett, S; Lunau, K

    1985-04-01

    Shape sensing is useful in the computer aided prosthetic fitting process for two purposes. 1. To input characteristic prosthetic shapes that have been developed over the years through the experience of prosthetists. 2. To provide an accurate and rapid measurement of the anatomical shape of the stump. This paper describes two instruments which have been built to meet these objectives.

  19. Technology and Jobs: Computer-Aided Design. Numerical-Control Machine-Tool Operators. Office Automation.

    Science.gov (United States)

    Stanton, Michael; And Others

    1985-01-01

    Three reports on the effects of high technology on the nature of work include (1) Stanton on applications and implications of computer-aided design for engineers, drafters, and architects; (2) Nardone on the outlook and training of numerical-control machine tool operators; and (3) Austin and Drake on the future of clerical occupations in automated…

  20. MULTI-AGENT COMPUTER AIDED ASSEMBLY PROCESS PLANNING SYSTEM FOR SHIP HULL

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A multi-agent computer aided assembly process planning system (MCAAPP) for ship hull is presented. The system includes system framework, global facilitator, the macro agent structure, agent communication language, agent-oriented programming language, knowledge representation and reasoning strategy. The system can produce the technological file and technological quota, which can satisfy the production needs of factory.

  1. Incorporating Computer-Aided Software in the Undergraduate Chemical Engineering Core Courses

    Science.gov (United States)

    Alnaizy, Raafat; Abdel-Jabbar, Nabil; Ibrahim, Taleb H.; Husseini, Ghaleb A.

    2014-01-01

    Introductions of computer-aided software and simulators are implemented during the sophomore-year of the chemical engineering (ChE) curriculum at the American University of Sharjah (AUS). Our faculty concurs that software integration within the curriculum is beneficial to our students, as evidenced by the positive feedback received from industry…

  2. Effect of Computer-Aided Instruction on Attitude and Achievement of Fifth Grade Math Students

    Science.gov (United States)

    Shoemaker, Traci L.

    2013-01-01

    The purpose of this quasi-experimental non-equivalent control group study was to test theories of constructivism and motivation, along with research-based teaching practices of differentiating instruction and instructing within a child's Zone of Proximal Development, in measuring the effect of computer-aided instruction on fifth grade students'…

  3. Effect of Computer-Aided Perspective Drawings on Spatial Orientation and Perspective Drawing Achievement

    Science.gov (United States)

    Kurtulus, Aytac

    2011-01-01

    The aim of this study is to investigate the effect of computer-aided Perspective Drawings on eighth grade primary school students' achievement in Spatial Orientation and Perspective Drawing. The study made use of pre-test post-test control group experimental design. The study was conducted with thirty 8th grade students attending a primary school…

  4. Computer-Aided College Algebra: Learning Components that Students Find Beneficial

    Science.gov (United States)

    Aichele, Douglas B.; Francisco, Cynthia; Utley, Juliana; Wescoatt, Benjamin

    2011-01-01

    A mixed-method study was conducted during the Fall 2008 semester to better understand the experiences of students participating in computer-aided instruction of College Algebra using the software MyMathLab. The learning environment included a computer learning system for the majority of the instruction, a support system via focus groups (weekly…

  5. The Computer-Aided Analytic Process Model. Operations Handbook for the Analytic Process Model Demonstration Package

    Science.gov (United States)

    1986-01-01

    Research Note 86-06 THE COMPUTER-AIDED ANALYTIC PROCESS MODEL : OPERATIONS HANDBOOK FOR THE ANALYTIC PROCESS MODEL DE ONSTRATION PACKAGE Ronald G...ic Process Model ; Operations Handbook; Tutorial; Apple; Systems Taxonomy Mod--l; Training System; Bradl1ey infantry Fighting * Vehicle; BIFV...8217. . . . . . . .. . . . . . . . . . . . . . . . * - ~ . - - * m- .. . . . . . . item 20. Abstract -continued companion volume-- "The Analytic Process Model for

  6. Data Management Standards in Computer-aided Acquisition and Logistic Support (CALS)

    Science.gov (United States)

    Jefferson, David K.

    1990-01-01

    Viewgraphs and discussion on data management standards in computer-aided acquisition and logistic support (CALS) are presented. CALS is intended to reduce cost, increase quality, and improve timeliness of weapon system acquisition and support by greatly improving the flow of technical information. The phase 2 standards, industrial environment, are discussed. The information resource dictionary system (IRDS) is described.

  7. Increasing computer-aided detection specificity by projection features for CT colonography

    OpenAIRE

    Zhu, Hongbin; Liang, Zhengrong; Pickhardt, Perry J.; Barish, Matthew A.; You, Jiangsheng; Fan, Yi; Lu, Hongbing; Posniak, Erica J.; Richards, Robert J.; Cohen, Harris L.

    2010-01-01

    Purpose: A large number of false positives (FPs) generated by computer-aided detection (CAD) schemes is likely to distract radiologists’ attention and decrease their interpretation efficiency. This study aims to develop projection-based features which characterize true and false positives to increase the specificity while maintaining high sensitivity in detecting colonic polyps.

  8. A Computer-Aided Self-Testing System for Biological Psychology.

    Science.gov (United States)

    Leiblum, M. D.; And Others

    1994-01-01

    Describes the production of a computer-aided, self-testing system for university students enrolled in a first-year course in biological psychology. Project aspects described include selection, acquisition and description of software; question banks and test structures; modes of use (computer or printed version); evaluation; and future plans. (11…

  9. SMART USE OF COMPUTER-AIDED SPERM ANALYSIS (CASA) TO CHARACTERIZE SPERM MOTION

    Science.gov (United States)

    Computer-aided sperm analysis (CASA) has evolved over the past fifteen years to provide an objective, practical means of measuring and characterizing the velocity and parttern of sperm motion. CASA instruments use video frame-grabber boards to capture multiple images of spermato...

  10. Experiments Using Cell Phones in Physics Classroom Education: The Computer-Aided "g" Determination

    Science.gov (United States)

    Vogt, Patrik; Kuhn, Jochen; Muller, Sebastian

    2011-01-01

    This paper continues the collection of experiments that describe the use of cell phones as experimental tools in physics classroom education. We describe a computer-aided determination of the free-fall acceleration "g" using the acoustical Doppler effect. The Doppler shift is a function of the speed of the source. Since a free-falling objects…

  11. Comparative evaluation of support vector machine classification for computer aided detection of breast masses in mammography

    NARCIS (Netherlands)

    Lesniak, J.M.; Hupse, R.; Blanc, R.; Karssemeijer, N.; Sz\\'ekely, G.

    2012-01-01

    False positive (FP) marks represent an obstacle for effective use of computer-aided detection (CADe) of breast masses in mammography. Typically, the problem can be approached either by developing more discriminative features or by employing different classifier designs. In this paper, the usage of s

  12. The Effects of Computer-Aided Concept Cartoons and Outdoor Science Activities on Light Pollution

    Science.gov (United States)

    Aydin, Güliz

    2015-01-01

    The purpose of this study is to create an awareness of light pollution on seventh grade students via computer aided concept cartoon applications and outdoor science activities and to help them develop solutions; and to determine student opinions on the practices carried out. The study was carried out at a middle school in Mugla province of Aegean…

  13. Incorporating Computer-Aided Software in the Undergraduate Chemical Engineering Core Courses

    Science.gov (United States)

    Alnaizy, Raafat; Abdel-Jabbar, Nabil; Ibrahim, Taleb H.; Husseini, Ghaleb A.

    2014-01-01

    Introductions of computer-aided software and simulators are implemented during the sophomore-year of the chemical engineering (ChE) curriculum at the American University of Sharjah (AUS). Our faculty concurs that software integration within the curriculum is beneficial to our students, as evidenced by the positive feedback received from industry…

  14. Persons with Alzheimer's Disease Make Phone Calls Independently Using a Computer-Aided Telephone System

    Science.gov (United States)

    Perilli, Viviana; Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Cassano, Germana; Cordiano, Noemi; Pinto, Katia; Minervini, Mauro G.; Oliva, Doretta

    2012-01-01

    This study assessed whether four patients with a diagnosis of Alzheimer's disease could make independent phone calls via a computer-aided telephone system. The study was carried out according to a non-concurrent multiple baseline design across participants. All participants started with baseline during which the telephone system was not available,…

  15. [Comparison of two computer-aided recording systems: MT 1602 and Compugnath].

    Science.gov (United States)

    Pröbster, L; Benzing, U

    1990-07-01

    Two computer-aided jaw movement recording systems were compared with each other. The results showed that both systems work satisfactorily for use in reconstructive dentistry and TMJ diagnosis. It is, however, emphasized, that there are a number of shortcomings which may have a negative effect on the recordings.

  16. A Multidisciplinary Research Team Approach to Computer-Aided Drafting (CAD) System Selection. Final Report.

    Science.gov (United States)

    Franken, Ken; And Others

    A multidisciplinary research team was assembled to review existing computer-aided drafting (CAD) systems for the purpose of enabling staff in the Design Drafting Department at Linn Technical College (Missouri) to select the best system out of the many CAD systems in existence. During the initial stage of the evaluation project, researchers…

  17. Computer-Aided Air-Traffic Control In The Terminal Area

    Science.gov (United States)

    Erzberger, Heinz

    1995-01-01

    Developmental computer-aided system for automated management and control of arrival traffic at large airport includes three integrated subsystems. One subsystem, called Traffic Management Advisor, another subsystem, called Descent Advisor, and third subsystem, called Final Approach Spacing Tool. Data base that includes current wind measurements and mathematical models of performances of types of aircraft contributes to effective operation of system.

  18. A Computer-Aided Self-Testing System for Biological Psychology.

    Science.gov (United States)

    Leiblum, M. D.; And Others

    1994-01-01

    Describes the production of a computer-aided, self-testing system for university students enrolled in a first-year course in biological psychology. Project aspects described include selection, acquisition and description of software; question banks and test structures; modes of use (computer or printed version); evaluation; and future plans. (11…

  19. Computer-Aided Detection in Breast Magnetic Resonance Imaging: A Review

    NARCIS (Netherlands)

    Dorrius, M. D.; Van Ooijen, P.M.A.

    2008-01-01

    The aim of this study is to give an overview on the accuracy of the discrimination between benign and malignant breast lesions on MRI with and without the use of a computer-aided detection (CAD) system. One investigator selected relevant articles based on title and abstract. Ten articles were select

  20. Possible Computer Vision Systems and Automated or Computer-Aided Edging and Trimming

    Science.gov (United States)

    Philip A. Araman

    1990-01-01

    This paper discusses research which is underway to help our industry reduce costs, increase product volume and value recovery, and market more accurately graded and described products. The research is part of a team effort to help the hardwood sawmill industry automate with computer vision systems, and computer-aided or computer controlled processing. This paper...

  1. Computer-aided detection of small pulmonary nodules in chest radiographs: an observer study.

    NARCIS (Netherlands)

    Boo, D.W. De; Uffmann, M.; Weber, M.; Bipat, S.; Boorsma, E.F.; Scheerder, M.J.; Freling, N.J.; Schaefer-Prokop, C.M.

    2011-01-01

    RATIONALE AND OBJECTIVES: To evaluate the impact of computer-aided detection (CAD, IQQA-Chest; EDDA Technology, Princeton Junction, NJ) used as second reader on the detection of small pulmonary nodules in chest radiography (CXR). MATERIALS AND METHODS: A total of 113 patients (mean age 62 years) wit

  2. Computer Aided Design of Kaplan Turbine Piston with\tSolidWorks

    Directory of Open Access Journals (Sweden)

    Camelia Jianu

    2010-10-01

    Full Text Available The paper presents the steps for 3D computer aided design (CAD of Kaplan turbine piston made in SolidWorks.The present paper is a tutorial for a Kaplan turbine piston 3D geometry, which is dedicaded to the Parts Sketch and Parts Features design and Drawing Geometry and Drawing Annotation.

  3. Computer aided molecular design with combined molecular modeling and group contribution

    DEFF Research Database (Denmark)

    Harper, Peter Mathias; Gani, Rafiqul; Kolar, Petr

    1999-01-01

    Computer-aided molecular design (CAMD) provides a means for determining molecules or mixtures of molecules (CAMMD) having a desirable set of physicochemical properties. The application range of CAMD is restricted due to limitations on the complexity of the generated molecular structures and on th...

  4. Virtual Reality versus Computer-Aided Exposure Treatments for Fear of Flying

    Science.gov (United States)

    Tortella-Feliu, Miquel; Botella, Cristina; Llabres, Jordi; Breton-Lopez, Juana Maria; del Amo, Antonio Riera; Banos, Rosa M.; Gelabert, Joan M.

    2011-01-01

    Evidence is growing that two modalities of computer-based exposure therapies--virtual reality and computer-aided psychotherapy--are effective in treating anxiety disorders, including fear of flying. However, they have not yet been directly compared. The aim of this study was to analyze the efficacy of three computer-based exposure treatments for…

  5. A-mode ultrasound-based registration in computer-aided surgery of the skull.

    Science.gov (United States)

    Amstutz, Christoph; Caversaccio, Marco; Kowal, Jens; Bächler, Richard; Nolte, Lutz-Peter; Häusler, Rudolf; Styner, Martin

    2003-12-01

    To evaluate the integration and accuracy of A (amplitude)-mode ultrasound-based surface matching for noninvasive registration of the head into a frameless computer-aided surgery system for otorhinology and skull base surgery. Experimental study and case series. Academic medical center. Twelve patients underwent anterior and paranasal skull base surgery with the routine use of a computer-aided surgery system. A computer-aided surgery system, based on an optoelectronic localizer, was used to track the skull and the surgical tools, including the A-mode ultrasound probe. The A-mode probe was a 10-MHz immersion transducer. An acoustic lens attached to the transducer focused the ultrasonic beam to a depth of 1 to 10 mm. Accuracy tests were performed for the ultrasound setup. Different surface point distributions were evaluated with respect to matching accuracy on a human cadaver skull specimen equipped with fiducial markers. The matching comparison was based on the fiducial registration error. For the clinical evaluation, the laboratory setup was transferred to the operating room. Noninvasive registration of the skull by using A-mode ultrasound in computer-aided surgery (practical and clinical measurements). The accuracy tests on the human skull specimen revealed that the mean +/- SD fiducial registration error was 1.00 +/- 0.19 mm in the best series for A-mode ultrasound surface matchings and was robust with respect to different sets of surface points. The mean +/- SD root mean square error from the 12 A-mode ultrasound matchings in the patient study was 0.49 +/- 0.20 mm. A-mode ultrasound surface matching can be used as a noninvasive and accurate registration procedure in computer-aided surgery of the head.

  6. 影像导航鼻内镜系统在鼻内翻性乳头状瘤和鼻窦骨瘤中的应用%The application of an image guidance endoscopic system for nasal inverted papilloma and sinus osteoma

    Institute of Scientific and Technical Information of China (English)

    李忠万; 高明华; 李朝军; 李劲松; 方红雁

    2014-01-01

    目的:分析采用影像导航进行鼻内翻性乳头状瘤、鼻窦骨瘤鼻内镜手术与传统鼻内镜手术的疗效。方法73例鼻腔内翻性乳头状瘤、鼻窦骨瘤患者被分成导航组与非导航组,导航组采用影像导航下鼻内镜手术,非导航组采用传统鼻内镜手术。分析两组患者的手术时间、麻醉时间、术中出血量、并发症及术后疗效情况。结果导航组与非导航组患者麻醉时间比较,差异无统计学意义(P>0.05),手术时间、术中出血量比较,差异有统计学意义(P<0.05)。鼻腔内翻性乳头状瘤导航组与非导航组Ⅰ、Ⅱ级复发率比较,差异无统计学意义(P>0.05),而在Ⅲ、Ⅳ级中复发率比较,差异有统计学意义(P<0.05)。鼻窦骨瘤中非导航组有1例复发,导航组未见复发病例。鼻腔内翻性乳头状瘤中导航组与非导航组鼻内并发症比较,差异有统计学意义(P<0.05),Ⅰ、Ⅱ级鼻内并发症导航组与非导航组的发生率比较,差异无统计学意义(P>0.05),而在Ⅲ、Ⅳ级鼻内并发症的发生率比较,差异有统计学意义(P<0.05)。在鼻窦骨瘤中导航组与非导航组鼻内并发症比较,差异有统计学意义(P<0.05)。结论对于鼻窦骨瘤及Ⅲ、Ⅳ级鼻腔内翻性乳头状瘤,影像导航下鼻内镜手术优于传统鼻内镜手术,特别在术前评价和确保手术中的安全性方面起到了有价值的辅助作用,使得肿瘤切除更彻底,复发率更低。%Objective To evaluate the clinical effect of image guided navigation system (IGNS) and traditional methods for nasal inverted papilloma and sinus osteoma .Methods 73 cases of nasal inverted papilloma and sinus osteoma patients were divided into the navigation group and the non-navigation group ,the navigation group was given image guidance endoscopic sinus surgery ,the non-navigation group was given

  7. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... is painless, noninvasive and accurate. It’s also the most reliable imaging technique for determining if the sinuses ... CT scan of the sinuses, the patient is most commonly positioned lying flat on the back. The ...

  8. Complications of Sinusitis

    Science.gov (United States)

    ... Hay Fever) Headaches and Sinus Disease Disorders of Smell & Taste Upper Respiratory Infections Nasal Congestion & Snoring CSF ... Hay Fever) Headaches and Sinus Disease Disorders of Smell & Taste Upper Respiratory Infections Nasal Congestion & Snoring CSF ...

  9. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... the limitations of CT of the Sinuses? What is CT (Computed Tomography) of the Sinuses? Computed tomography, ... the body being studied. top of page How is the procedure performed? The technologist begins by positioning ...

  10. [Maxillary sinus hypoplasia].

    Science.gov (United States)

    Plaza, G; Ferrando, J; Martel, J; Toledano, A; de los Santos, G

    2001-03-01

    Maxillary sinus hypoplasia is rare, with an estimated prevalence of 1-5%. Out of the CT scans performed in sinusal patients between March 1998 and June 1999, we report on 4 isolated maxillary sinus hypoplasia, 4 maxillary sinus hypoplasia associated to concha bullosa, and 10 isolated conchae bullosas. All cases were evaluated by nasosinusal endoscopy and CT scan. Size, location and uni/bilateral presentation of concha bullosa is correlated to maxillary sinus hypoplasia presence, specially with regards to uncinate process presence, medial or lateral retraction. The pathogenesis of maxillary sinus hypoplasia is reviewed, and its relation to concha bullosa, evaluating how this could explain some cases of the so called chronic maxillary sinus atelectasia, as an acquired and progressive variant of maxillary sinus hypoplasia in adults.

  11. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... modality for sinusitis. CT of the sinuses is now widely available and is performed in a relatively short time, especially when compared to magnetic resonance imaging (MRI). ...

  12. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... determining if the sinuses are obstructed and the best imaging modality for sinusitis. Tell your doctor if ... over time. Follow-up examinations are sometimes the best way to see if treatment is working or ...

  13. Sinusitis in adults - aftercare

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000563.htm Sinusitis in adults - aftercare To use the sharing features ... Bending forward with your head down Allergies and Sinusitis Allergies that are not well-controlled can make ...

  14. Approaching chronic sinusitis.

    Science.gov (United States)

    Sarber, Kathleen M; Dion, Gregory Robert; Weitzel, Erik K; McMains, Kevin C

    2013-11-01

    Chronic sinusitis is a common disease that encompasses a number of syndromes that are characterized by sinonasal mucosal inflammation. Chronic sinusitis can be defined as two or more of the following symptoms lasting for more than 12 consecutive weeks: discolored rhinorrhea, postnasal drip, nasal obstruction, facial pressure or pain, or decreased sense of smell. Chronic sinusitis is further classified as chronic sinusitis with polyposis, chronic sinusitis without polyposis, or allergic fungal sinusitis using physical examination, and histologic and radiographic findings. Treatment methods for chronic sinusitis are based upon categorization of the disease and include oral and inhaled corticosteroids, nasal saline irrigations, and antibiotics in selected patients. Understanding the various forms of chronic sinusitis and managing and ruling out comorbidities are key to successful management of this common disorder.

  15. The Computer-Aided Analytic Process Model. Operations Handbook for the APM (Analytic Process Model) Demonstration Package. Appendix

    Science.gov (United States)

    1986-01-01

    The Analytic Process Model for System Design and Measurement: A Computer-Aided Tool for Analyzing Training Systems and Other Human-Machine Systems. A...separate companion volume--The Computer-Aided Analytic Process Model : Operations Handbook for the APM Demonstration Package is also available under

  16. Histoplasma capsulatum sinusitis.

    OpenAIRE

    1997-01-01

    Sinusitis is commonly reported in patients with AIDS. In addition to the usual bacterial pathogens isolated from immunocompetent patients, sinusitis in patients with AIDS may be caused by a variety of unusual bacteria, viruses, fungi, parasites, and mycobacteria. Histoplasma capsulatum has not typically been associated with sinusitis in either group of patients. We report a case of sinusitis caused by H. capsulatum in a patient with AIDS.

  17. Computed Tomography (CT) -- Sinuses

    Medline Plus

    Full Text Available ... equipment to evaluate the paranasal sinus cavities – hollow, air-filled spaces within the bones of the face surrounding the ... paranasal sinus cavities. The paranasal sinuses are hollow, air-filled spaces located within the bones of the face and ...

  18. CT-based manual segmentation and evaluation of paranasal sinuses.

    Science.gov (United States)

    Pirner, S; Tingelhoff, K; Wagner, I; Westphal, R; Rilk, M; Wahl, F M; Bootz, F; Eichhorn, Klaus W G

    2009-04-01

    Manual segmentation of computed tomography (CT) datasets was performed for robot-assisted endoscope movement during functional endoscopic sinus surgery (FESS). Segmented 3D models are needed for the robots' workspace definition. A total of 50 preselected CT datasets were each segmented in 150-200 coronal slices with 24 landmarks being set. Three different colors for segmentation represent diverse risk areas. Extension and volumetric measurements were performed. Three-dimensional reconstruction was generated after segmentation. Manual segmentation took 8-10 h for each CT dataset. The mean volumes were: right maxillary sinus 17.4 cm(3), left side 17.9 cm(3), right frontal sinus 4.2 cm(3), left side 4.0 cm(3), total frontal sinuses 7.9 cm(3), sphenoid sinus right side 5.3 cm(3), left side 5.5 cm(3), total sphenoid sinus volume 11.2 cm(3). Our manually segmented 3D-models present the patient's individual anatomy with a special focus on structures in danger according to the diverse colored risk areas. For safe robot assistance, the high-accuracy models represent an average of the population for anatomical variations, extension and volumetric measurements. They can be used as a database for automatic model-based segmentation. None of the segmentation methods so far described provide risk segmentation. The robot's maximum distance to the segmented border can be adjusted according to the differently colored areas.

  19. Chronic Maxillary Sinusitis Associated with an Unusual Foreign Body: A Case Report

    Directory of Open Access Journals (Sweden)

    Yunus Feyyat Şahin

    2012-01-01

    Full Text Available Foreign bodies in maxillary sinuses are unusual clinical conditions, and they can cause chronic sinusitis by mucosal irritation. Most cases of foreign bodies in maxillary sinus are related to iatrogenic dental manipulation and only a few cases with non-dental origin are reported. Oroantral fistulas secondary to dental procedures are the most common way of insertion. Treatment is surgical removal of the foreign body either endoscopically or with a combined approach, with Caldwell-Luc procedure if endoscopic approach is inadequate for visualisation. In this case, we present a 24-year-old male patient with unilateral chronic maxillary sinusitis due to a wooden toothpick in left maxillary sinus. The patient had a history of upper second premolar tooth extraction. CT scan revealed sinus opacification with presence of a foreign body in left maxillary sinus extending from the floor of the sinus to the orbital base. The foreign body, a wooden toothpick, was removed with Caldwell-Luc procedure since it was impossible to remove the toothpick endoscopically. There was no obvious oroantral fistula in the time of surgery, but the position of the toothpick made us to think that it was inserted through a previously healed fistula, willingly or accidentally.

  20. Custom-Made Computer-Aided-Design/Computer-Aided-Manufacturing Biphasic Calcium-Phosphate Scaffold for Augmentation of an Atrophic Mandibular Anterior Ridge

    Directory of Open Access Journals (Sweden)

    Francesco Guido Mangano

    2015-01-01

    Full Text Available This report documents the clinical, radiographic, and histologic outcome of a custom-made computer-aided-design/computer-aided-manufactured (CAD/CAM scaffold used for the alveolar ridge augmentation of a severely atrophic anterior mandible. Computed tomographic (CT images of an atrophic anterior mandible were acquired and modified into a 3-dimensional (3D reconstruction model; this was transferred to a CAD program, where a custom-made scaffold was designed. CAM software generated a set of tool-paths for the manufacture of the scaffold on a computer-numerical-control milling machine into the exact shape of the 3D design. A custom-made scaffold was milled from a synthetic micromacroporous biphasic calcium phosphate (BCP block. The scaffold closely matched the shape of the defect: this helped to reduce the time for the surgery and contributed to good healing. One year later, newly formed and well-integrated bone was clinically available, and two implants (AnyRidge, MegaGen, Gyeongbuk, South Korea were placed. The histologic samples retrieved from the implant sites revealed compact mature bone undergoing remodelling, marrow spaces, and newly formed trabecular bone surrounded by residual BCP particles. This study demonstrates that custom-made scaffolds can be fabricated by combining CT scans and CAD/CAM techniques. Further studies on a larger sample of patients are needed to confirm these results.